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Sample records for larsson yves lemoigne

  1. Jean-Yves Hemery

    CERN Multimedia

    CERN Bulletin

    2010-01-01

    The family, friends and colleagues of Jean-Yves HEMERY are sad to announce his accidental death on 24 September, at the age of 63, in Priziac. A funeral service has already taken place in his native region of Brittany and a commemoration will be held at the Mairie de Cessy, on Tuesday 12 October at 1.30 p.m., prior to the burial at the cemetery. Jean-Yves joined CERN in 1973 and worked first at the ISR for ten years and then on the beam instrumentation at LEP. The last twelve years of his career were his most fulfilling as he did great work on the beam design for the LEAR facility at the PS. Since retiring in 2007 his main occupation had been the renovation of his small house in Brittany. His Family and friends

  2. Hommage à Yves Laporte

    OpenAIRE

    Berthoz, Alain; Glowinski, Jacques; Prochiantz, Alain

    2014-01-01

    Yves Laporte est né à Toulouse le 21 décembre 1920. Durant la seconde guerre mondiale, il a été membre de la Résistance française et après sa démobilisation de la 1ère Armée Française, il se voit décerner en 1945 la Médaille de la Résistance et la Croix de guerre. Sur les conseils d'Alfred Fessard, alors titulaire de la chaire de Neurophysiologie au Collège de France, il part pour deux ans aux états-Unis où, grâce à un soutien des relations culturelles puis comme boursier de la Fondation Roc...

  3. ABBA, Volvo, Lindgren... ja Larsson / Urve Eslas

    Index Scriptorium Estoniae

    Eslas, Urve

    2009-01-01

    Arvustus: Larsson, Stieg. Tüdruk, kes mängis tulega / rootsi keelest tõlkinud Kadri Papp. Tallinn : Varrak, 2009 ; Larsson, Stieg. Lohetätoveeringuga tüdruk : põnevusromaan. Tallinn : Varrak, 2009

  4. Grafmeyer Yves, Authier Jean-Yves, Sociologie urbaine

    Directory of Open Access Journals (Sweden)

    Anaïs Van Sull

    2011-02-01

    Full Text Available Yves Grafmeyer et Jean-Yves Authier ont consacré la plupart de leurs travaux de recherche aux questions de l’espace urbain et de la socialisation qui y prend place. L’ouvrage qu’ils proposent, enrichi et actualisé par rapport à la première édition, aborde les différents objets, méthodes et problématiques qui peuvent être insérés dans le champ de la sociologie urbaine. S’ils reconnaissent une large part d’arbitraire dans les concepts et courants retenus, on ne peut que se réjouir des nouvelles...

  5. Yves Bernard (1954-2014)

    CERN Multimedia

    2014-01-01

    Yves Bernard, who has passed away at the age of 59, worked in the transport and handling service (EN-HE) and had been at CERN since 1 July 1975.   Yves Bernard, CERN Open Day 2008. He initially worked for the various transport companies on site, such as H. Reigner, ISS, DBS and ALTEAD, during which time he quickly climbed the ladder (from driver to team leader to foreman) before becoming a member of the CERN personnel in 2004. He was also a volunteer firefighter at the Grilly-Divonne fire station. He worked on all the large accelerator and experiment worksites, in particular on the installation of DELPHI and the North Area (UA1, UA2, UA5), on the Meyrin site (ISR, ISOLDE, AD, the CTF3 complex, n_TOF, LINAC4) and on consolidation work (PS, East Area, PSB). Always friendly and open, he was well-known by many people all over CERN. If ever you had a transport problem, he was the man to call. His commitment to the Organization meant he always went the extra mile to help out physicists and users....

  6. Genetics Home Reference: Sjögren-Larsson syndrome

    Science.gov (United States)

    ... Email Facebook Twitter Home Health Conditions Sjögren-Larsson syndrome Sjögren-Larsson syndrome Printable PDF Open All Close All ... FALDH deficiency fatty aldehyde dehydrogenase deficiency ichthyosis oligophrenia syndrome Sjogren-Larsson syndrome SLS Related Information How are genetic ...

  7. OPHTHALMIC FINDINGS IN LATE STAGE SJOGREN-LARSSON SYNDROME.

    Science.gov (United States)

    Nanda, Tavish; Kovach, Jaclyn L

    2017-03-15

    To report spectral domain optical coherence tomography and fundus autofluorescence documentation of late stage macular findings associated with Sjogren-Larsson Syndrome in three adult siblings. Three adult siblings with Sjogren-Larsson Syndrome underwent ophthalmic examination and imaging. Crystalline maculopathy and subretinal deposits, presumably lipofuscin accumulation, with macular atrophy were present in varying degrees in all three adult siblings. In adults with Sjogren-Larsson Syndrome, crystalline retinopathy can progress to macular atrophy and the appearance of lipofuscin accumulation.

  8. Hommage à Yves Laporte (1920-2012)

    OpenAIRE

    Berthoz, Alain; Glowinski, Jacques; Prochiantz, Alain

    2014-01-01

    Yves Laporte est né à Toulouse le 21 décembre 1920. Durant la Seconde Guerre mondiale, il a été membre de la Résistance française et après sa démobilisation de la 1re armée française, il se voit décerner en 1945 la médaille de la Résistance et la Croix de guerre. Sur les conseils d’Alfred Fessard, alors titulaire de la chaire de Neurophysiologie au Collège de France, il part pour deux ans aux États-Unis où, grâce à un soutien des relations culturelles puis comme boursier de la fondation Rocke...

  9. Sjogren-Larsson syndrome: Report of two cases

    Directory of Open Access Journals (Sweden)

    Uppal Monica

    2004-03-01

    Full Text Available Two cases of Sjogren-Larsson syndrome are discussed along with a review of the literature. Both the patients had generalized ichthyosis, spastic paraplegia, mental retardation and ophthalmologic examination showing glistening foveal and parafoveal dots.

  10. We’re all behind you, Jean-Yves!

    CERN Document Server

    Laëtitia Pedroso

    2010-01-01

    Jean-Yves Le Meur, developer of the CERN Document Server (CDS) which manages the Organization’s electronic archives, is about to take part in his third Paralympic Winter Games in Vancouver. Don’t miss him on TV from 15th March onwards !   Jean-Yves, second from the right, participates in a five-day IT training programme in Rwanda. Jean-Yves Le Meur won his place in the 14-strong “Team France” (11 men and 3 women) that will compete at the 2010 Paralympic Winter Games in Vancouver via the qualifying events held in Austria and Italy in 2009. “It was really tough to get selected this time round. You either had to make a top-three finish in a World Cup event or win gold at the European Cup”, says Jean-Yves.     Jean-Yves will be competing in four alpine skiing events: the "Super G" (Super Giant Slalom), the Super Combined Slalom, the Giant Slalom and the Slalom. And given his good performances in ...

  11. Sjogren-Larsson syndrome: A rare neurocutaneous disorder

    Directory of Open Access Journals (Sweden)

    Velusamy Subramanian

    2016-01-01

    Full Text Available Sjogren-Larsson syndrome is an autosomal recessive disorder characterized by defective activity of fatty aldehyde dehydrogenase. It presents as a triad of congenital ichthyosis, spastic diplegia, and mental retardation. The pathology behind this syndrome is the failure of degradation of fatty aldehydes. This case is presented for its rarity.

  12. Sjogren-Larsson syndrome: A rare neurocutaneous disorder.

    Science.gov (United States)

    Subramanian, Velusamy; Hariharan, Praveen; Balaji, J

    2016-01-01

    Sjogren-Larsson syndrome is an autosomal recessive disorder characterized by defective activity of fatty aldehyde dehydrogenase. It presents as a triad of congenital ichthyosis, spastic diplegia, and mental retardation. The pathology behind this syndrome is the failure of degradation of fatty aldehydes. This case is presented for its rarity.

  13. Speech-language performance in Sjogren-Larsson syndrome.

    NARCIS (Netherlands)

    Fuijkschot, J.; Maassen, B.; Gorter, J.W.; Gerven, M.A.J. van; Willemsen, M.

    2009-01-01

    OBJECTIVE: To describe speech-language pathology in patients with Sjogren-Larsson syndrome (SLS) in relation to their cognitive and motor impairment. DESIGN: Observational case series. METHODS: Cognitive functioning was assessed in 16 patients with SLS (nine males; seven females) using different neu

  14. Travail et pouvoir d’agir d’Yves Clot

    Directory of Open Access Journals (Sweden)

    Jacques Leplat

    2008-11-01

    Full Text Available Yves Clot est titulaire de la Chaire de psychologie du travail du Conservatoire National des Arts et Métiers (CNAM au sein duquel il dirige l’équipe de clinique de l’activité. Cet ouvrage est le second qu’il publie dans cette collection, le premier « La fonction psychologique du travail » est paru en 1999. Entre les deux s’inscrivent un grand nombre de publications, dont beaucoup avec d’autres chercheurs, comme on pourra le constater en consultant la bibliographie de ce livre. Ce denier réun...

  15. Síndrome Sjögren - Larsson

    Directory of Open Access Journals (Sweden)

    Leonardo Portela Rabello

    2011-12-01

    Full Text Available Relatam-se os casos de dois irmãos consanguíneos com síndrome de Sjögren- Larsson, enfatizando a importância clínica do exame oftalmológico. BPLS, masculino, 11 anos e MBLS, feminino, 10 anos, irmãos de pais não-consanguíneos, apresentando ictiose congênita, diplegia espástica e retardo mental. Ao exame oftalmológico, apresentavam miopia, fotofobia, baixa acuidade visual. A fundoscopia, presença de cristais branco-amarelados em área foveal e parafoveal em ambos os olhos. Aconselhamento genético foi realizado. O manejo foi de suporte. A Síndrome de Sjögren-Larsson é uma rara doença autossômica recessiva em que há 100% de penetrância. Síndrome de Sjögren-Larsson é classicamente caracterizada por ictiose, espasticidade e deficiência mental. A doença é causada por mutações no gene aldeído desidrogenase. As alterações oculares observadas são geralmente bilaterais, cristais branco-amarelados em área retiniana, que aparecem nos dois primeiros anos de vida e que vão aumentando em número com a idade. As anormalidades oculares não têm relação com a severidade da ictiose ou com as anormalidades neurológicas. Acredita-se que as lesões oftalmológicas sejam um sinal patognomônico da síndrome. É necessário enfatizar a importância do diagnóstico precoce e possibilidades de tratamento dietético.

  16. Yves Carlet. Stephen Crane. Les couleurs de l’angoisse.

    Directory of Open Access Journals (Sweden)

    Claude Dorey

    2006-04-01

    Full Text Available Il est heureux que les cendres de Stephen Crane entrent au panthéon de Marc Chénetier. Yves Carlet, l’ordonnateur, nous convie au « survol » d’une œuvre qu’il décrit comme un « commencement avorté ». Le trajet s’effectue au moyen d’oppositions binaires. Un axe de polarités contraires est, d’entrée, posé : d’un côté, la ligne morale de l’honnêteté réaliste, de l’autre, celle, baroque, du conteur ironique et nostalgique. Néanmoins une « cohérence profonde » dessinée par des « motifs obsédants »...

  17. Freaks Freearchitects / Yves Pasquet, Cyril Gauthier, Guillaume Aubry ; intervjueerinud Eve Arpo

    Index Scriptorium Estoniae

    Pasquet, Yves

    2016-01-01

    Prantsuse arhitektuuribüroost Freaks Freearchitects. Büroo arhitektid Yves Pasquet, Cyril Gauthier ja Guillaume Aubry tegelevad arhitekti rolli määratlemisega installatsioonide, filmi ning arhitektuursete projektide kaudu

  18. Territori di Babele. Aforismi sulla traduzione di Jean-Yves Masson

    Directory of Open Access Journals (Sweden)

    Riccardo Raimondo

    2015-05-01

    Full Text Available Jean-Yves Masson pubblica i suoi aforismi sulla traduttologia nel 1991. Attraverso questi inediti precetti, possiamo seguire un filo conduttore che si dipana dalle origini della riflessione sulla traduzione fino alle più recenti teorie.In 1991 Jean Yves Masson published his aphorisms on Translation Theory. Following these original guidelines, we are able to trace the developments of translation theory from its origins to the present.

  19. MRI of white matter changes in the Sjoegren-Larsson syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Hussain, M.Z. [Dept. of Radiology, Yamanashi Medical Coll., Yamanashi (Japan); Oba, H. [Dept. of Radiology, Yamanashi Medical Coll., Yamanashi (Japan); Ohtomo, K. [Dept. of Radiology, Yamanashi Medical Coll., Yamanashi (Japan); Aihara, M. [Dept. of Paediatrics, Yamanashi Medical Coll., Tamahocho, Yamanashi (Japan); Hayashibe, H. [Dept. of Paediatrics, Yamanashi Medical Coll., Tamahocho, Yamanashi (Japan); Nakazawa, S. [Dept. of Paediatrics, Yamanashi Medical Coll., Tamahocho, Yamanashi (Japan); Uchiyama, G. [Dept. of Radiology, Yamanashi Medical Coll., Yamanashi (Japan)

    1995-10-01

    We report a case of Sjoegren-Larsson syndrome with spastic diplegia and conduction aphasia. MRI demonstrated the white matter changes deep in the cerebral hemispheres. We analyse the MRI findings and compare the results with neuropsychological signs. (orig.)

  20. Portrait: Yves Sillanoli, Staff Association delegate since 2004

    CERN Document Server

    Staff Association

    2017-01-01

    Yves Sillanoli - Staff Association delegate. I worked at CERN as Contractor’s personnel for 18 years, and in 2003, I became a staff member. By nature, I am someone who enjoys getting involved in associations. For 35 years, I was a member of a sports association in my community. Therefore, for me it was natural to want to reach out and help my colleagues, especially those with professional experiences similar to mine. Moreover, even though both my father and my brother had worked at CERN before me, I really wanted to understand the inner functioning of the Organization. To this end, I decided to run for staff delegate and was elected to the Staff Association in 2004. Joining the Staff Association has been, above all, a chance to meet people: Gianni Deroma, former President of the Staff Association, and Philippe Defert, who passed away in 2013, were great listeners and had a real sense of mutual help. Philippe Defert influenced greatly my decision take part in the Association and, over time, a rema...

  1. De Manet a Yves Saint-Laurent: uma análise semiótica

    Directory of Open Access Journals (Sweden)

    Christiane Paula Godinho Santarelli

    2008-09-01

    Full Text Available A proposta deste artigo é fazer uma análise semiótica, com base na teoria greimasiana, da pintura original de Manet Le déjeuner sur l’herbe e de sua recriação para o anúncio da marca Yves Saint-Laurent. Os aspectos analisados nos dois “textos” são: os sistemas de valores, a estrutura narrativa, a estrutura de poder, os objetos de valor e a semântica profunda. A comparação dos dois discursos tem como objetivo atentar para as contradições no suposto discurso libertador da publicidade de Yves Saint-Laurent, que pode estar presente na publicidade de outras marcas. Palavras-chave: Publicidade; semiótica; arte; moda. ABSTRACT The purpose of this article is to offer a semiotical analysis of the original painting of Manet Le déjeuner sur l’herbe and of its recreation in an advertisement for the brand Yves Saint-Laurent. The aspects analyzed in the two “texts” are: the systems of enclosed values, the narrative structure, the power structure, the objects of value and deep semantics. The comparison between the two forms of speech aims to highlight the contradictions in the alleged liberating speech of the Yves Saint-Laurent advertisement, which may be present in advertising pieces from other brands. Keywords: Advertising; semiotics; art; fashion.

  2. Leadership in Modern Times: Reflections on Yves Cohen's Le siècle des chefs

    NARCIS (Netherlands)

    Föllmer, M.

    2014-01-01

    This review article discusses Yves Cohen’s recent book Le siècle des chefs: Une histoire transnationale du commandement et de l’autorité (1890-1940 ). Cohen provides an extensive analysis of discourses on leadership in France, the Soviet Union, Germany and the United States. He also studies how lead

  3. Leadership in Modern Times: Reflections on Yves Cohen's Le siècle des chefs

    NARCIS (Netherlands)

    M. Föllmer

    2014-01-01

    This review article discusses Yves Cohen’s recent book Le siècle des chefs: Une histoire transnationale du commandement et de l’autorité (1890-1940 ). Cohen provides an extensive analysis of discourses on leadership in France, the Soviet Union, Germany and the United States. He also studies how lead

  4. MR spectroscopy and diffusion tensor imaging of the brain in Sjogren-Larsson syndrome

    NARCIS (Netherlands)

    Sijens, P. E.; Westerlaan, H. E.; de Groot, J. C.; Boon, M.; Potze, J. H.; van Spronsen, F. J.; Lunsing, R. J.; Oudkerk, M.

    2009-01-01

    Diffusion tensor imaging (DTI) is reported for the first time in a patient with Sjogren-Larsson syndrome, an autosomal recessive neurocutaneous disorder. Magnetic resonance spectroscopy (MRS) revealed normal levels of choline, creatine and N-acetyl aspartate (NAA) and the characteristic lipid signal

  5. Sjogren-Larsson syndrome: motor performance and everyday functioning in 17 patients.

    NARCIS (Netherlands)

    Verhoog, J.; Fuijkschot, J.; Willemsen, M.; Ketelaar, M.; Rotteveel, J.; Gorter, J.W.

    2008-01-01

    Sjogren-Larsson syndrome (SLS) is an autosomal recessive neurometabolic disorder characterized by spasticity, learning disability, and ichthyosis. To our knowledge, there is no detailed report in the literature concerning the functional consequences of SLS. Therefore, we performed a cross-sectional

  6. Sjogren-Larsson syndrome: motor performance and everyday functioning in 17 patients.

    NARCIS (Netherlands)

    Verhoog, J.; Fuijkschot, J.; Willemsen, M.; Ketelaar, M.; Rotteveel, J.; Gorter, J.W.

    2008-01-01

    Sjogren-Larsson syndrome (SLS) is an autosomal recessive neurometabolic disorder characterized by spasticity, learning disability, and ichthyosis. To our knowledge, there is no detailed report in the literature concerning the functional consequences of SLS. Therefore, we performed a cross-sectional

  7. Sjogren-Larsson syndrome : motor performance and everyday functioning in 17 patients

    NARCIS (Netherlands)

    Verhoog, Judith; Fuijkschot, Joris; Willemsen, Michel; Ketelaar, Marjolijn; Rotteveel, Jan; Gorter, Jan Willem

    Sjogren-Larsson syndrome (SLS) is an autosomal recessive neurometabolic disorder characterized by spasticity, learning disability, and ichthyosis. To our knowledge, there is no detailed report in the literature concerning the functional consequences of SLS. Therefore, we performed a cross-sectional

  8. Meeting with Jean-Yves Le Meur, author of "Faux Pas"

    CERN Multimedia

    2008-01-01

    A CERN engineer and an accomplished sportsman, Jean-Yves Le Meur (IT Department) has recently published his first book "Faux pas". Meet him and hear about his exceptional life on 23 April 2008 in the Globe. An accident cost him his legs when he was young, and it was sheer force of character and a passion for the mountains that carried Jean-Yves Le Meur, with one artificial leg and crutches to stay upright, to the very summit of the Mont-Blanc. In his book, Jean-Yves, a computer engineer at CERN, recounts with detachment his personal battle to win back his life and make this impossible ascent. "Faux Pas" depicts a series of encounters and people, and recreates the extreme emotions of a man who reconstructed his life and pushed himself beyond his limits. It is a moving personal account, whose message is universal. The question-and-answer session with the author will be preceded by the projection of "4810M, CAHIN-CAHA",...

  9. Karl Gustaf Torsten Sjögren and the Sjögren-Larsson syndrome

    Directory of Open Access Journals (Sweden)

    Khalid Al Aboud

    2011-09-01

    Full Text Available Karl Gustaf Torsten Sjögren (1896-1974 a Swedish psychiatrist and geneticist, was a pioneer of modern Swedish psychiatry. Sjögren studied medicine at the University of Uppsala. From 1932 to 1935, he was Head Physician and Director of Lillehagen Hospital in Gothenburg, and between 1935- 1945, he was physician-in-chief at the psychiatric department of Sahlgrenska Hospital in Gothenburg. Sjögren was professor of psychiatry at Karolinska Institutet from 1945 to 1961 and was elected to the Royal Swedish Academy of Sciences in 1951. Sjögren was an expert of psychiatry for the World Health Organization. Among his many contributions to medicine, he is credited for describing several medical conditions, which were later named after him, including Graefe- Sjögren syndrome, Marinesco-Sjögren syndrome, and Sjögren-Larsson syndrome (SLS. During his work on juvenile amaurotic idiocy, Sjögren forged a collaboration with Tage K.L. Larsson, a statistics lecturer at the University of Lund. Their study on the combination of oligophrenia, congenital ichthyosis, and spastic disorders in 1957 established the clinical and genetic profile of a new disease entity, later known as Sjogren-Larsson syndrome (SLS.

  10. A Saussurean Solution: Embodying 'Presence' in Yves Bonnefoy’s Poetics

    Directory of Open Access Journals (Sweden)

    Layla Roesler

    2015-11-01

    Full Text Available This paper uses the work of contemporary French poet Yves Bonnefoy to examine the difficulty of making poetry carry the burden of transmitting a position that is, at least in part, philosophical. Bonnefoy’s work is characterized by his strong affirmation of the notion of “presence” which, he argues, can genuinely inhabit the poetic text, allowing readers to directly obtain an experience of it. He is, however, intensely aware of the barrier erected by language. His solution is to use the tools of Saussurean linguistics to suggest a means by which presence might inhabit the text.

  11. Chansons Stop; Chanson mise en espace; Chanson-Collages; Avoir trente ans...avec Yves Duteil (Hitchhiking Songs; Song Diagramming; Song-Collages; To Be Thirty...With Yves Duteil).

    Science.gov (United States)

    Pulluard-Gallin, Monique; And Others

    1984-01-01

    Four articles provide ideas for specific classroom activities using songs, including discussion based on two popular hitchhiking songs, appreciation of the elements and structure of a song representative of the new "French song," making collages representing songs, and analysis of the treatment of age in Yves Duteil's songs. (MSE)

  12. A rare case of Sjogren-Larsson syndrome with recurrent pneumonia and asthma

    OpenAIRE

    Tavasoli, Azita; Sayyahfar, Shirin; Behnam, Babak

    2016-01-01

    Sjogren-Larsson syndrome (SLS) is a rare autosomal recessive neurocutaneous disorder with worldwide incidence of 0.4 per 100,000 people. It is characterized by the triad of congenital ichthyosis, spastic diplegia or quadriplegia, and mental retardation. Herein we report a 2-year-old male child with SLS, asthma, and recurrent pneumonia. SLS was confirmed by a molecular genetics study that revealed a deletion mutation in the ALDH3A2 gene. An ALDH3A2 gene mutation results in dysfunction of the m...

  13. Sjögren-Larsson syndrome: importance of early diagnosis and aggressive physiotherapy.

    Science.gov (United States)

    Kathuria, Sushruta; Arora, Shikha; Ramesh, V

    2012-09-15

    Sjögren-Larsson syndrome (SLS) is a congenital ichthyotic disorder with spasticity. We describe a case of a 5-year-old boy with SLS diagnosed clinically based on congenital ichythosis, quadriplegia, and mental retardation. The child responded well to emollients and antihistamines. His quadriplegia was managed by aggressive physiotherapy and mental retardation by stimulation techniques. After a 3-year follow up, significant improvement was seen in his motor and mental disability. This case highlights the importance of clinical diagnosis and early intervention for such a disabling disorder.

  14. The importance of hydraulic groundwater theory in catchment hydrology: The legacy of Wilfried Brutsaert and Jean-Yves Parlange

    NARCIS (Netherlands)

    Troch, P.A.A.; Berne, A.D.; Harman, C.; Hilberts, A.G.J.; Lyon, S.W.; Paniconi, C.; Pauwels, V.R.N.; Rupp, D.E.; Selker, J.S.; Teuling, A.J.; Uijlenhoet, R.; Verhoest, N.E.C.

    2013-01-01

    Based on a literature overview, this paper summarizes the impact and legacy of the contributions of Wilfried Brutsaert and Jean-Yves Parlange (Cornell University) with respect to the current state-of-the-art understanding in hydraulic groundwater theory. Forming the basis of many applications in cat

  15. The importance of hydraulic groundwater theory in catchment hydrology: The legacy of Wilfried Brutsaert adn Jean-Yves Parlange

    NARCIS (Netherlands)

    Troch, P.A.; Berne, A.; Bogaart, P.W.; Harman, C.; Hilberts, A.G.J.; Lyon, S.W.; Paniconi, C.; Pauwels, V.R.N.; Rupp, D.E.; Selker, J.S.; Teuling, A.J.; Uijlenhoet, R.; Verhoest, N.E.C.

    2013-01-01

    Based on a literature overview, this paper summarizes the impact and legacy of the contributions of Wilfried Brutsaert and Jean-Yves Parlange (Cornell University) with respect to the current state-of-the-art understanding in hydraulic groundwater theory. Forming the basis of many applications in cat

  16. The importance of hydraulic groundwater theory in catchment hydrology: The legacy of Wilfried Brutsaert adn Jean-Yves Parlange

    NARCIS (Netherlands)

    Troch, P.A.; Berne, A.; Bogaart, P.W.; Harman, C.; Hilberts, A.G.J.; Lyon, S.W.; Paniconi, C.; Pauwels, V.R.N.; Rupp, D.E.; Selker, J.S.; Teuling, A.J.; Uijlenhoet, R.; Verhoest, N.E.C.

    2013-01-01

    Based on a literature overview, this paper summarizes the impact and legacy of the contributions of Wilfried Brutsaert and Jean-Yves Parlange (Cornell University) with respect to the current state-of-the-art understanding in hydraulic groundwater theory. Forming the basis of many applications in cat

  17. Allegory and Event: Two ways of saying the salamander in Yves Bonnefoy

    Directory of Open Access Journals (Sweden)

    Layla Roesler

    2010-07-01

    Full Text Available L’article examine l’idée d’événement à travers la figure de la salamandre dans l’œuvre d’Yves Bonnefoy. L’image, saisissante en elle-même, est rendue plus significative encore par le fait qu’elle franchit les frontières séparant habituellement les genres littéraires. Son apparition à la fois dans un essai et dans un cycle de poèmes tend à l’ancrer dans la réalité d’un événement vécu. Nous proposons de voir dans la juxtaposition des deux textes non seulement une narration qui prend l’événement vécu en charge, mais l’agencement même des possibilités permettant de reconnaître l’événement comme tel.This paper addresses the notion of event through the prism of Yves Bonnefoy’s salamander trope. This arresting image is all the more memorable because it crosses the boundaries of generic separations, appearing both in an essay as well as in an early poetry collection. The fact that an identical image should be reiterated in such formally disparate structures seems to point insistently to its reality as a material event. I argue that juxtaposing the two texts reveals both a narration recounting an event and, simultaneously, the ordering of possibilities leading to its recognition as event.El artículo examina la idea del acontecimiento a través de la figura de la salamandra en la obra de Yves Bonnefoy. La imagen, sorprendente en sí misma, se vuelve más significativa aún debido al hecho de que cruza las fronteras que separan generalmente los géneros literarios. Su presencia tanto en un ensayo como en un ciclo de poemas tiende a situarla en la realidad de un acontecimiento vivido. En la yuxtaposición de los dos textos proponemos ver no sólo una narración que asume el acontecimiento vivido, sino también la disposición misma de las posibilidades que permiten reconocer al acontecimiento como tal.

  18. Yves-Charles Grandjeat. John Edgar Wideman. Le feu et la neige.

    Directory of Open Access Journals (Sweden)

    Nathalie Cochoy

    2009-12-01

    Full Text Available John Edgar Wideman, auteur noir américain contemporain, est généralement connu en France pour la complexité de son écriture. L’œuvre de Wideman paraît en effet déroutante : le brouillage vertigineux des repères narratifs, la porosité des frontières entre réalité et fiction, la dislocation soudaine de la syntaxe, emportée par la violence d’un témoignage ou par la pulsation d’un blues, brisent les modes de pensée et de lecture traditionnels. Or, selon Yves-Charles Grandjeat, auteur de ce très b...

  19. Yves Bonnefoy et la communauté des mères

    OpenAIRE

    Cavallini, Concetta

    2016-01-01

    A Gianmarco,car ce sont les enfants qui font les mères. Yves Bonnefoy semble très lié à l’idée de partage et de communauté s’il est vrai qu’après le titre célèbre donné à un ensemble d’articles consacrés à la traduction et au travail du traducteur (La communauté des traducteurs), il a choisi La communauté des critiques comme titre d’un recueil très récemment publié sur le travail de certains critiques et historiens de la littérature (tels Claude Pichois, Marcel Raymond, Gaëtan Picon, Georges ...

  20. Novel mutation in Sjogren-Larsson syndrome is associated with divergent neurologic phenotypes.

    Science.gov (United States)

    Davis, Kathleen; Holden, Kenton R; S'Aulis, Dana; Amador, Claudia; Matheus, M Gisele; Rizzo, William B

    2013-10-01

    Sjögren-Larsson syndrome is an inherited disorder of lipid metabolism caused by mutations in the ALDH3A2 gene that codes for fatty aldehyde dehydrogenase, which results in accumulation of fatty aldehydes and alcohols and is characterized by ichthyosis, intellectual disability, and spastic diplegia/quadriplegia. The authors describe 2 unrelated Honduran patients who carried the same novel homozygous nonsense mutation (c.1309A>T, p.K437X) and ALDH3A2 DNA haplotype, but widely differed in disease severity. One patient exhibited spastic quadriplegia with unusual neuroregression, whereas the other patient had the usual static form of spastic diplegia with neurodevelopmental disabilities. Biochemical analyses showed a similar profound deficiency of fatty aldehyde dehydrogenase activity and impaired fatty alcohol metabolism in both patients' cultured fibroblasts. These results indicate that variation in the neurologic phenotype of Sjögren-Larsson syndrome is not strictly determined by the ALDH3A2 mutation or the biochemical defect as expressed in cultured fibroblasts, but by unidentified epigenetic/environmental factors, gene modifiers, or other mechanisms.

  1. Understanding fetal factors that contribute to preterm birth: Sjögren-Larsson syndrome as a model.

    Science.gov (United States)

    Staps, Pippa; Hogeveen, Marije; Fuijkschot, Joris; van Drongelen, Joris; Willemsen, Michèl A A P

    2017-09-15

    Preterm birth is the world's leading cause of neonatal death. Unfortunately, the pathophysiology of preterm birth remains poorly understood. Sjögren-Larsson syndrome is a rare, neurometabolic disorder caused by a fatty aldehyde dehydrogenase deficiency. A majority of patients with Sjögren-Larsson syndrome is born preterm. Data of all known Dutch patients with Sjögren-Larsson syndrome and all cases reported in literature were analyzed to learn from preterm birth in context of this rare disease. Exact gestational age was known in 33 Dutch patients; 24 (73%) of them were born preterm, with a median gestational age of 36 weeks. The literature search confirmed our findings: 13 (59%) of 22 cases was born preterm. Preterm birth is a hallmark of Sjögren-Larsson syndrome, presumably caused by the abnormal lipid metabolism of the fetus. At least five additional rare genetic disorders (namely Ehlers-Danlos syndrome, ichthyosis prematurity syndrome, congenital analbuminemia, osteogenesis imperfecta type II and restrictive dermopathy) were found in literature that lead to preterm birth of the affected fetus. These disorders are in fact "experiments of nature" and as such they shed new lights on the mechanisms causing preterm birth.

  2. Between Liberalism and Nationalism in Mexico: the Economic Thought of José Yves Limantour

    Directory of Open Access Journals (Sweden)

    Iliana Marcela Quintanar Zárate

    2016-02-01

    Full Text Available The objective of this paper is to ascertain the principles of the economic thinking of José Yves Limantour, and the changes they underwent, to explain the process of transformation of econo- mic liberalism which, as will be seen, tended more toward state intervention; this, incidentally, can be considered as the basis of economic nationalism as developed by the post-revolutionary governments. It follows, then, that the study of Limantour and his economic thinking seeks to explain the transformation process to which the Mexican liberal state was subjected in thelast decade of the 19th century and the first decade of the 20th. The study is divided into two sections, the first of which explores the general characteristics of the liberal state and its transfor- mations from the 1850s through to the 1900s. The second analyses the spheres of the Mexican economy that constituted the main focuses of Limantour’s interventions and regulation.

  3. Síndrome de Sjögren-Larsson: estudo clínico e laboratorial de dois casos

    OpenAIRE

    Maria Joaquina Marques-Dias; Antonio Branco Lefèvre; Claudete H. Gonzalez; Pedro Henrique Saldanha

    1983-01-01

    São registrados dois casos, irmãos e um de cada sexo, com ictiose de aparecimento precoce, deficiência mental, diplegia espática e alterações nos fundos oculares. A associação destes sinais sem outros concomitantes levam ao diagnóstico do síndrome de Sjögren e Larsson.

  4. Síndrome de Sjögren-Larsson: estudo clínico e laboratorial de dois casos

    Directory of Open Access Journals (Sweden)

    Maria Joaquina Marques-Dias

    1983-12-01

    Full Text Available São registrados dois casos, irmãos e um de cada sexo, com ictiose de aparecimento precoce, deficiência mental, diplegia espática e alterações nos fundos oculares. A associação destes sinais sem outros concomitantes levam ao diagnóstico do síndrome de Sjögren e Larsson.

  5. MRI and ¹H-MRS findings of three patients with Sjögren-Larsson syndrome

    OpenAIRE

    Mauro Nakayama; Távora,Daniel G.F.; Alvim,Thereza C.L.; Araújo,Alexandre C.B.; Gama,Rômulo L.

    2006-01-01

    Sjögren-Larsson syndrome (SLS) is a rare autosomal recessive neurocutaneous disorder caused by deficiency of the microsomal enzyme fatty aldehyde dehydrogenase. Patients present the classical triad of congenital ichthyosis, mental retardation and spastic di- or tetraplegia. Magnetic resonance imaging (MRI) of the brain usually shows hypomyelination involving the periventricular white matter. Cerebral proton MR spectroscopy (¹H-MRS) reveals a characteristic abnormal lipid peak. We report three...

  6. A rare case of Sjogren-Larsson syndrome with recurrent pneumonia and asthma.

    Science.gov (United States)

    Tavasoli, Azita; Sayyahfar, Shirin; Behnam, Babak

    2016-06-01

    Sjogren-Larsson syndrome (SLS) is a rare autosomal recessive neurocutaneous disorder with worldwide incidence of 0.4 per 100,000 people. It is characterized by the triad of congenital ichthyosis, spastic diplegia or quadriplegia, and mental retardation. Herein we report a 2-year-old male child with SLS, asthma, and recurrent pneumonia. SLS was confirmed by a molecular genetics study that revealed a deletion mutation in the ALDH3A2 gene. An ALDH3A2 gene mutation results in dysfunction of the microsomal enzyme fatty aldehyde dehydrogenase and impaired metabolism and accumulation of leukotriene B4, which is a key molecule and a pro-inflammatory mediator in developing allergic diseases, especially asthma. An increased level of leukotriene B4 has been reported in SLS patients. As far as we are aware, this is the first report of SLS associated with asthma and recurrent pneumonia. In conclusion, pediatricians should be aware of and evaluate patients with SLS for possible associated asthma and allergic disorders.

  7. Large contiguous gene deletions in Sjögren-Larsson syndrome.

    Science.gov (United States)

    Engelstad, Holly; Carney, Gael; S'aulis, Dana; Rise, Janae; Sanger, Warren G; Rudd, M Katharine; Richard, Gabriele; Carr, Christopher W; Abdul-Rahman, Omar A; Rizzo, William B

    2011-11-01

    Sjögren-Larsson syndrome (SLS) is an autosomal recessive disorder characterized by ichthyosis, mental retardation, spasticity and mutations in the ALDH3A2 gene for fatty aldehyde dehydrogenase, an enzyme that catalyzes the oxidation of fatty aldehyde to fatty acid. More than 70 mutations have been identified in SLS patients, including small deletions or insertions, missense mutations, splicing defects and complex nucleotide changes. We now describe 2 SLS patients whose disease is caused by large contiguous gene deletions of the ALDH3A2 locus on 17p11.2. The deletions were defined using long distance inverse PCR and microarray-based comparative genomic hybridization. A 24-year-old SLS female was homozygous for a 352-kb deletion involving ALDH3A2 and 4 contiguous genes including ALDH3A1, which codes for the major soluble protein in cornea. Although lacking corneal disease, she showed severe symptoms of SLS with uncommon deterioration in oral motor function and loss of ambulation. The other 19-month-old female patient was a compound heterozygote for a 1.44-Mb contiguous gene deletion and a missense mutation (c.407C>T, P136L) in ALDH3A2. These studies suggest that large gene deletions may account for up to 5% of the mutant alleles in SLS. Geneticists should consider the possibility of compound heterozygosity for large deletions in patients with SLS and other inborn errors of metabolism, which has implications for carrier testing and prenatal diagnosis.

  8. Strong allelic association between Sjoegren-Larsson syndrome and D17S805

    Energy Technology Data Exchange (ETDEWEB)

    Pigg, M.; Jagell, S.; Sillen, A. [University Hospital, Uppsala (Sweden)] [and others

    1994-09-01

    Sjoegren-Larsson Syndrom (SLS) is characterized by congenital ichthyosis, spastic di- or tetraplegia and mental retardation. It is an autosomal recessive trait that has been described in many populations, but is particularly frequent in the northern part of Sweden. A defect in the enzyme fatty alcohol: NAD+ oxidoreductase (FAD) has been suggested, but the molecular mechanism has not been elucidated. Based on linkage analysis and allelic association, the disorder has now been mapped to chromosome 17. Meiotic recombinations suggests that the gene is flanked by D17S805 on the centromeric and D17S783 and D17S925 on the telomeric side. These three markers map to the same location in reference pedigrees. Strong allelic association (chi-square 60.28, p<0.0003) to D17S805 suggests that the mutation is located at a limited distance on the telomeric side of this marker. It is possible that the gene can be identified by functional complementation of SLS cells using YACs from this region. Alternatively, positional cloning should be possible in this presumable small area. The markers identified are close and informative enough to allow accurate genetic diagnosis.

  9. Influence of environmental gradients on the distribution of benthic resources available for shorebirds on intertidal mudflats of Yves Bay, France

    Science.gov (United States)

    Philippe, Anne S.; Pinaud, David; Cayatte, Marie-Laure; Goulevant, Cyril; Lachaussée, Nicolas; Pineau, Philippe; Karpytchev, Mikhail; Bocher, Pierrick

    2016-06-01

    The case study of Yves Bay (Pertuis Charentais, France) highlighted links between environmental gradients (i.e. sediment characteristics and emersion time) and prey distribution and availability for the two most numerous shorebird species overwintering in Yves Bay: the red knot Calidris canutus and the dunlin Calidris alpina. Two hundred and fifty-two stations were sampled on a predetermined 250 m regular grid covering the intertidal mudflats of this major wintering site in France for east-Atlantic migratory shorebirds. The distribution of principal benthic species abundance and biomass was modelled along two environmental gradients: sediment structure (particularly pronounced north-south sand-mud gradient) and emersion time. The effect of emersion time combined with sedimentary structure strongly explained abundances and biomasses of the main prey for C. canutus and C. alpina in the bay (Cerastoderma edule, Hydrobia ulvae, Macoma balthica, Scrobicularia plana, and Nephtys hombergii). This study highlighted prey species-specific spatial segregation/overlapping as well as spatial interferences in the trophic niche of the two shorebirds.

  10. A Turkish family with Sjögren-Larsson syndrome caused by a novel ALDH3A2 mutation

    Directory of Open Access Journals (Sweden)

    Faruk Incecik

    2013-01-01

    Full Text Available Sjögren-Larsson syndrome (SLS is an inherited neurocutaneous disorder caused by mutations in the aldehyde dehydrogenase family 3 member A2 (ALDH3A2 gene that encodes fatty aldehyde dehydrogenase. Affected patients display ichthyosis, mental retardation, and spastic diplegia. More than 70 mutations in ALDH3A2 have been discovered in SLS patients. We diagnosed two brothers age of 12 and 20 years with characteristic features of this rare syndrome. Magnetic resonance imaging showed demyelinating disease in both of them. We described a novel homozygous, c. 835 T > A (p.Y279N mutation in exon 6 in two patients.

  11. Sjögren-Larsson syndrome: novel mutations in the ALDH3A2 gene in a French cohort.

    Science.gov (United States)

    Sarret, Catherine; Rigal, Mélanie; Vaurs-Barrière, Catherine; Dorboz, Imen; Eymard-Pierre, Eléonore; Combes, Patricia; Giraud, Geneviève; Wanders, Ronald J A; Afenjar, Alexandra; Francannet, Christine; Boespflug-Tanguy, Odile

    2012-01-15

    Sjogren-Larsson syndrome (SLS) is a rare autosomal recessive disorder characterized by ichthyosis, spastic di- or tetraplegia and mental retardation due a defect of the fatty aldehyde dehydrogenase (FALDH), related to mutations in the ALDH3A2 gene. In this study, we screened a French cohort of patients with Sjögren-Larsson syndrome (SLS) for mutations in the ALDH3A2 gene. The five unrelated patients with typical SLS all present mutations in this gene. Three novel mutations were identified whereas three other ones were previously described. We also realized functional analyses at the mRNA level for two splice site mutations to study their deleterious consequences. Two of the previously described mutations had already been identified in the same region of Europe, suggesting a putative founder effect. We suggest that, (1) when clinical and MR features are present, direct sequencing of the ALDH3A2 gene in SLS is of particular interest without necessity of a skin biopsy for enzymatic assay in order to propose genetic counsel and (2) identification of mutations already described in the same population with putative founder effects may simplify genetic analysis in this context.

  12. The road to universal logic festschrift for 50th birthday of Jean-Yves Béziau

    CERN Document Server

    Buchsbaum, Arthur

    2015-01-01

    This is the first volume of a collection of papers in honor of the fiftieth birthday of Jean-Yves Béziau. These 25 papers have been written by internationally distinguished logicians, mathematicians, computer scientists, linguists and philosophers, including Arnon Avron, John Corcoran, Wilfrid Hodges, Laurence Horn, Lloyd Humbertsone, Dale Jacquette, David Makinson, Stephen Read, and Jan Woleński. It is a state-of-the-art source of cutting-edge studies in the new interdisciplinary field of universal logic. The papers touch upon a wide range of topics including combination of logic, non-classical logic, square and other geometrical figures of opposition, categorical logic, set theory, foundation of logic, philosophy and history of logic (Aristotle, Avicenna, Buridan, Schröder, MacColl). This book offers new perspectives and challenges in the study of logic and will be of interest to all students and researchers interested the nature and future of logic.

  13. Une idée simple. Une grande idée! Réflexions sur Björn Larsson: La place et le sens des adjectifs épithètes de valorisation positive

    DEFF Research Database (Denmark)

    Nølke, Henning

    1997-01-01

    En review-artikel af Björn Larssons bog om det attributive adjektivs stilling på fransk. Efter grundige empiriske undersøgelser af en lang række autentiske eksempler fremsætter Björn Larsson en hyopotese om, at adjektivets ekstention spiller en en afgørende rolle for dets placering: Jo større adj...

  14. Distrofia macular cristalina em paciente com síndrome de Sjögren-Larsson: relato de caso Macular crystalline dystrophy in Sjögren-Larsson syndrome: case report

    Directory of Open Access Journals (Sweden)

    David Leonardo Cruvinel Isaac

    2009-04-01

    Full Text Available Apresentação de um caso de distrofia macular cristalina em paciente do sexo feminino com síndrome de Sjögren-Larsson. A doença caracteriza-se pela tríade: ictiose congênita, diplegia ou tetraplegia espástica e retardo mental. Os olhos são acometidos em até 100% dos casos sendo característica a presença de maculopatia cristalina como observado na paciente relatada. À fundoscopia observou-se a presença de depósitos esbranquiçados perifoveais. A tomografia de coerência óptica evidenciou pontos hiper-reflexivos correspondentes aos depósitos intrarretinianos, atrofia macular com redução na espessura macular em ambos os olhos. Os achados relacionados à síndrome, à tomografia de coerência óptica foram apresentados de maneira inédita em nosso meio.Presentation of a case of crystalline macular distrophy diagnosed in a female patient with Sjögren-Larsson syndrome. The disease consists of clinical findings of spastic diplegia or tetraplegia, mental retardation, and congential ichthyosis. The eyes are affected in up to 100% of cases, and crystalline maculopathy is the main finding as described in this case report. On fundus examination multiple white dots were observed at ophthalmoscopy. The optical coherence tomography has shown not only the hipereflexive intraretinal spots but also macular atrophy with macular thickness reduction. The tomographic findings were first described in our country.

  15. Historia y poética del best-seller : la trilogía Millenium de Stieg Larsson

    OpenAIRE

    Vidal Vázquez, Rosa María

    2014-01-01

    La tesis Historia y poética del best-seller. La trilogía Millennium, de Stieg Larsson consta de dos partes que tratan de resumir la historia del superventas concretándose en un best-seller contemporáneo. La primera parte se basa en la conceptualización del término y un panorama de esta producción; el agente femenino como impulsor de la novela popular; y la poética de tres novelas superventas anteriores al siglo XXI, de distina época y país. La segunda parte analiza la trilogía Miiennium, estu...

  16. Les petits travailleurs du siècle : Sur Petites natures mortes au travail (2000 d’Yves Pagès

    Directory of Open Access Journals (Sweden)

    Isabelle Bernard-Rabadi

    2012-01-01

    Full Text Available Many of the fictions of Yves Pagès claim a taste for political controversy and claims libertarians: Petites natures mortes au travail (2000 is one of them. Composed of 24 short stories, this fiction is written without exacerbating militancy but shows through the mode of fragment new world of work, where workers rush to part-time in entertainment industry. All Characters are contractors, unemployed at the end of Rights and precarious. I will follow a tri-axial plan to show that the writer Yves Pagès with his serie of painting develops a gallery of the working class of the French at the end of the XXth Century. The first part will explicit the poetic of fragment, the second will draw a provocative portrait of Pagès and the third will explain the changing world of real work in terms of fiction.

  17. Leadership in Modern Times. Reflections on Yves Cohen’s Le siècle des chefs

    Directory of Open Access Journals (Sweden)

    Moritz Föllmer

    2014-11-01

    Full Text Available This review article discusses Yves Cohen’s recent book Le siêcle des chefs: Une histoire transnationale du commandement et de l’autorité (1890-1940. Cohen provides an extensive analysis of discourses on leadership in France, the Soviet Union, Germany and the United States. He also studies how leadership was practiced, by French and Soviet factory directors as well as by Stalin himself. While giving due credit to the scope and sophistication of his book, the review article asks whether Cohen’s focus on scientific discourses and highly structured organisations leaves sufficient room for contingency. It argues that interwar political leadership in interwar Europe was not least about seeing and seizing opportunities in unforeseeable circumstances, often thriving on a positive fascination with crises and states of emergency. It also points out that, contrary to what the combined title and subtitle suggest, “le siècle des chefs” hardly ended in 1939, and that the quest for leadership continues to preoccupy present-day societies, cultures and polities.

  18. Interview with Yves Pomeau, Boltzmann Medallist 2016 : The universality of statistical physics interpretation is ever more obvious.

    Science.gov (United States)

    Pomeau, Yves; Louët, Sabine

    2016-06-01

    During the StatPhys Conference on 20th July 2016 in Lyon, France, Yves Pomeau and Daan Frenkel will be awarded the most important prize in the field of Statistical Mechanics: the 2016 Boltzmann Medal, named after the Austrian physicist and philosopher Ludwig Boltzmann. The award recognises Pomeau's key contributions to the Statistical Physics of non-equilibrium phenomena in general. And, in particular, for developing our modern understanding of fluid mechanics, instabilities, pattern formation and chaos. He is recognised as an outstanding theorist bridging disciplines from applied mathematics to statistical physics with a profound impact on the neighbouring fields of turbulence and mechanics. In the article Sabine Louët interviews Pomeau, who is an Editor for the European Physical Journal Special Topics. He shares his views and tells how he experienced the rise of Statistical Mechanics in the past few decades. He also touches upon the need to provide funding to people who have the rare ability to discover new things and ideas, and not just those who are good at filling in grant application forms.

  19. Meeting of Directors and Heads of Department from CEA-Saclay, France

    CERN Multimedia

    Patrice Loïez

    2002-01-01

    Left to right: Ph. Pradelles, M. Jacquemet and T. Taylor in discussion during the December visit of Directors and Heads of Department from the Saclay centre of the French atomic energy commission (CEA) to CERN's LHC magnet test facility. Looking on is Yves Lemoigne.

  20. Current approach to Sjgren-Larsson syndrome%Sjogren-Larsson综合征研究进展

    Institute of Scientific and Technical Information of China (English)

    陈昕; 赵国华; 唐北沙

    2002-01-01

    @@ Sjogren-Larsson综合征(Sjgren-Larsson syndrome, SLS)是一种少见的神经皮肤疾病,由Sjgren和Larsson于1956年首先报道,其主要临床特点为先天性鱼鳞病,双下肢痉挛性截瘫或四肢瘫,智力发育障碍,眼睛异常等.该综合征以瑞典北部发病率较高,该地区的患病率达 8.3/10万,杂合子频率约2%.该病呈常染色体隐性遗传,是由于微粒体脂肪醛脱氢酶(fatty aldehyde dehydrogenase,FALDH)的缺乏引起脂肪族醛酸代谢障碍所致.现就近年SLS在临床、病理、基因定位与克隆、发病机制、诊断、鉴别诊断、治疗等方面的进展作一综述.

  1. Commentary: ADHD and social disadvantage: an inconvenient truth? --a reflection on Russell et al. () and Larsson et al. ().

    Science.gov (United States)

    Nigg, Joel T; Craver, Lindsay

    2014-05-01

    In the 1950's, many experts believed hyperkinesis was a neurotic reaction to inner conflicts arising from early family experiences. In the 1990's, many experts believed ADHD to be 'genetic' (without a mechanistic explanation of what that meant). Both views appear naïve today in a scientific world grappling with the complexity of highly plastic gene expression, gene x environment interplay, and epigenetic, context-dependent emergence of psychopathology. Both views also fail to account for the uncomfortable fact that ADHD is also associated with social disadvantage - a level of analysis required in a developmental psychopathology approach. That developmental psychopathology approach, pioneered a generation ago, initially emphasized the accumulation of risk and protective factors, and emerged in a contemporary systemic approach that seeks to determine whether it is risk accumulation (e.g., allostatic load) or specific risk factors (e.g., family process) that mechanistically shape psychopathology. Despite the prominence of the developmental psychopathology perspective, the social context of ADHD is surprisingly neglected today. Both Russell et al. (this issue, 2014) and Larsson et al. (this issue, 2014) take strides toward remedying this state of affairs. © 2014 The Authors. Journal of Child Psychology and Psychiatry. © 2014 Association for Child and Adolescent Mental Health.

  2. La traducción de los nombres propios en Los hombres que no amaban a las mujeres de Stieg Larsson

    OpenAIRE

    Wallström, Jessica

    2011-01-01

    El tema de la tesina presentada es la traducción de los nombres propios en la novela Los hombres que no amaban a las mujeres de Stieg Larsson. El objetivo de la tesina es ver cómo los nombres propios son traducidos y ver si un lector hispanohablante pierde o no el significado sobreentendido o las asociaciones que puedan tener los nombres propios. El método es análisis de texto, usamos tanto el análisis cuantitativo como el análisis cualitativo. Contamos la frecuencia de los nombres propios en...

  3. Os lugares do vazio: impressões antagônigas nos espaços de Georges Perec e Yves Klein

    Directory of Open Access Journals (Sweden)

    Manlio de Medeiros Speranzini

    2013-12-01

    Full Text Available Este trabalho toma o livro Un homme qui dort, de Georges Perec, e o texto “La spécialisation de la sensibilité à l’état matière première en sensibilité picturale stabilisée”, do artista Yves Klein, para explorar as maneiras como esses autores, um pela escrita e o outro pela intervenção em uma galeria de arte, sensibilizam os espaços para revelar o vazio. As ideias de Georges Didi-Huberman, presentes no livro O que vemos, o que nos olha, servem para esclarecer a natureza antagônica do vazio que as duas obras suscitam.

  4. Developmental patterns of emission of scent compounds and related gene expression in roses of the cultivar Rosa x hybrida cv. 'Yves Piaget'.

    Science.gov (United States)

    Chen, Xiaomin; Baldermann, Susanne; Cao, Shuyan; Lu, Yao; Liu, Caixia; Hirata, Hiroshi; Watanabe, Naoharu

    2015-02-01

    2-Phenylethanol (2PE) and 3,5-dimethoxytoluene (DMT) are characteristic scent compounds in specific roses such as Rosa x hybrida cv. 'Yves Piaget'. We analyzed the endogenous concentrations and emission of 2PE and DMT during the unfurling process in different floral organs, as well as changes in transcript levels of the two key genes, PAR and OOMT2. The emission of both 2PE and DMT increased during floral development to reach peaks at the fully unfurled stage. The relative transcripts of PAR and OOMT2 also increased during floral development. Whereas the maximum for OOMT2 was found at the fully unfurled stage (stage 4), similar expression levels of PAR were detected at stage 4 and the senescence stage (stage 6). The results demonstrate a positive correlation between the expression levels of PAR and OOMT2 and the emission of 2PE and DMT. In addition, endogenous volatiles and relative transcripts showed tissue- and development-specific patterns.

  5. MRI and ¹H-MRS findings of three patients with Sjögren-Larsson syndrome Síndrome de Sjögren-Larsson: achados à ressonância magnética e espectroscopia de prótons em três pacientes

    Directory of Open Access Journals (Sweden)

    Mauro Nakayama

    2006-06-01

    Full Text Available Sjögren-Larsson syndrome (SLS is a rare autosomal recessive neurocutaneous disorder caused by deficiency of the microsomal enzyme fatty aldehyde dehydrogenase. Patients present the classical triad of congenital ichthyosis, mental retardation and spastic di- or tetraplegia. Magnetic resonance imaging (MRI of the brain usually shows hypomyelination involving the periventricular white matter. Cerebral proton MR spectroscopy (¹H-MRS reveals a characteristic abnormal lipid peak. We report three cases of SLS from different families with the typical clinical triad. The MRI and ¹H-MRS findings are discussed.A síndrome de Sjögren-Larsson (SJL é distúrbio raro, autossômico recessivo, caracterizado pela tríade clássica de ictiose congênita, retardo mental e tetraplegia ou diplegia espástica. Trata-se de um erro inato do metabolismo dos lipídios, causado pela deficiência da enzima microssômica aldeído graxo desidrogenase. Os achados de imagem do encéfalo na SJL demonstram atrofia cerebral e alteração da substância branca. A espectroscopia de prótons, com poucos casos relatados, caracteriza-se pelo elevado pico de lipídios e redução de N-acetil-aspartato. Apresentamos três casos de SJL, com ênfase nos achados da ressonância magnética e da espectroscopia de prótons.

  6. Genetic homogeneity in Sjoegren-Larsson syndrome: Linkage to chromosome 17p in families of different non-Swedish ethnic origins

    Energy Technology Data Exchange (ETDEWEB)

    Rogers, G.R.; Lee, M.; Compton, J.G. [and others

    1995-11-01

    Sjoegren-Larsson syndrome (SLS) is a rare, autosomal recessive disorder that is characterized by congenital ichthyosis, mental retardation, and spastic diplegia or tetraplegia. Three United States families, three Egyptian families, and one Israeli Arab family were investigated for linkage of the SLS gene to a region of chromosome 17. Pairwise and multipoint linkage analysis with nine markers mapped the SLS gene to the same region of the genome as that reported in Swedish SLS pedigrees. Examination of recombinants by haplotype analysis showed that the gene lies in the region containing the markers D17S953, D17S805, D17S689, and D17S842. D17S805 is pericentromeric on 17p. Patients in two consanguineous Egyptian families were homozygous at the nine marker loci tested, and another patient from a third family was homozygous for eight of the nine, suggesting that within each of these families the region of chromosome 17 carrying the SLS gene is identical by descent. Linkage of the SLS gene to chromosome 17p in families of Arabic, mixed European, Native American, and Swedish descent provides evidence for a single SLS locus and should prove useful for diagnosis and carrier detection in worldwide cases. 25 refs., 4 figs., 1 tab.

  7. Sobre el arte y sus “estados físicos”: consideraciones acerca del libro “El arte en estado gaseoso. Ensayo sobre el triunfo de la estética” de Yves Michaud

    OpenAIRE

    2011-01-01

    “Este mundo es exageradamente bello”. Así es como Yves Michaud3 empieza su libro haciendo mención a la gran estetización de la vida que vivimos actualmente, tema de estelibro. Bellos pueden ser desde los empaques de los productos, pasando por los cuerpos reconstruidos o maquillados, hasta los cadáveres cuidadosamente envueltos en las ambulancias. Entre bromear y hablar en serio, Michaud reitera que los hombres del siglo XX hemos vivido bajo el triunfo de la estética y consecuentemente, de su ...

  8. Emmanuel Renault, Yves Sintomer (dir., Où en est la théorie critique ?, Paris, La Découverte, coll. « Recherches », 2003, 286 p., 31 €.

    Directory of Open Access Journals (Sweden)

    Alexandre Dupeyrix

    2005-04-01

    Full Text Available Dans l’introduction de cet ouvrage collectif publié en mars 2003, Emmanuel Renault et Yves Sintomer exposent leur volonté de « rendre compte de l’actualité d’un projet [celui de la théorie critique] tout en mettant en perspective les débats ouverts par les œuvres d’Habermas et de Honneth » (p. 10. On peut dire qu’ils ont pleinement réalisé leur ambition : l’ouvrage qu’ils proposent ici est une synthèse très riche et très stimulante des derniers travaux en cours sur la théorie critique et l’É...

  9. La question de la tolérance en Occident et en islam à travers le livre de Yves-Charles Zarka et Cynthia Fleury : Difficile tolérance

    Directory of Open Access Journals (Sweden)

    Makram Abbes

    2005-09-01

    Full Text Available Difficile tolérance est écrit par Yves-Charles Zarka avec la collaboration de Cynthia Fleury en vue d’étudier la question de la tolérance dans les sociétés occidentales et la place qu’occupent les communautés arabo-musulmanes au sein de ces sociétés. Les deux auteurs mettent l’accent sur l’incompatibilité entre les valeurs de l’Occident et celles de l’islam ; ils défendent l’idée de l’impossibilité de l’émergence de la tolérance dans la culture de l’islam et soulignent la nécessité de réagir face aux revendications communautaires, de plus en plus menaçantes pour la République. Cet article commente et discute les principaux postulats, présupposés et exemples historiques mobilisés par les deux auteurs. Il attire l’attention sur les erreurs de lecture, les contresens et les déformations au prix desquels les auteurs soutiennent leur thèse sur l’absence de la tolérance en islam.Yves-Charles Zarka and Cynthia Fleury’s Difficile tolérance seeks to study the question of tolerance within Western societies, and the position occupied by Arab Muslim communities within those societies. The authors stress the incompatibility of Western and Islamic values ; they argue that it is impossible for tolerance to develop within Islamic culture, and assert the need to react against communitarian claims, which they see as increasingly dangerous for the institutions of the French Republic. In this article, the main postulates, assumptions and historical examples put forward by Y. Zarka and C. Fleury are subjected to analysis and critique. The article points out the misreadings, errors of interpretation and distortions on which the two authors rely as they set out their hypothesis of the absence of tolerance within Islamic culture.

  10. Isolation of animal cell mutants defective in long-chain fatty aldehyde dehydrogenase. Sensitivity to fatty aldehydes and Schiff's base modification of phospholipids: implications for Sj-ogren-Larsson syndrome.

    Science.gov (United States)

    James, P F; Zoeller, R A

    1997-09-19

    Using tritium suicide, we have isolated a variant of the Chinese hamster ovary cell line, CHO-K1, that is deficient in long-chain fatty alcohol:NAD+ oxidoreductase (FAO; EC 1.1.1.192). Specifically, it was the fatty aldehyde dehydrogenase component that was affected. The enzymatic deficiency found in this mutant strain, designated FAA. K1A, was similar to that displayed by fibroblasts from patients with Sjögren-Larsson syndrome (SLS), an inheritable neurocutaneous disorder. Complementation analyses suggested that the deficiency in fatty alcohol oxidation in the FAA.K1A cells and the SLS fibroblasts is a result of lesions in homologous genes. The FAA.K1A cells were unable to convert long chain fatty aldehydes to the corresponding fatty acids. This resulted in a hypersensitivity of the FAA.K1A cells to the cytotoxic effects of long chain fatty aldehydes. The difference between the mutant and wild-type cells was most obvious when using fatty aldehydes between 14 and 20 carbons, with the greatest difference between wild-type and mutant cells found when using octadecanal. Fibroblasts from a patient with SLS also displayed the hypersensitivity phenotype when compared with FAldDH+ human fibroblasts. In both CHO and human FAldDH- cell lines, addition of long chain fatty aldehydes to the medium caused a dramatic increase in aldehyde-modified phosphatidylethanolamine, presumably through Schiff's base addition to the primary amine of the ethanolamine head group. When 25 microM hexadecanal was added to the growth medium, approximately 10% of the phosphatidylethanolamine was found in the fatty aldehyde-modified form in FAA.K1A, although this was not observed in wild-type cells. Modified phosphatidylethanolamine could be detected in FAldDH- cells even when exogenous fatty aldehydes were not added to the medium. We propose a possible role for fatty aldehydes, or other aldehydic species, in mediating some of the symptoms associated with Sjögren-Larsson syndrome.

  11. 2214-IJBCS-Article-Soko Yves

    African Journals Online (AJOL)

    hp

    (Fischer test, P > 0.05) in the body weights between the control and treated animals. These results ... mice compared to controls. MATERIALS .... behavior was rather strengthened compared to .... acute toxicity (decreased motor activity, pilo-.

  12. Sjogren - Larsson Syndrome : a case report.

    Directory of Open Access Journals (Sweden)

    Dhanuka A

    2002-07-01

    Full Text Available Two male siblings aged 8 and 11 years, born of non-consanguineous parents, presented with classical triad of congenital ichthyosis, mental retardation and spastic diplegia. They had no eye, hair, nails and teeth changes. MRI showed diffuse dysmyelination.

  13. Meeting of Directors and Heads of Department from CEA-Saclay, France

    CERN Multimedia

    Patrice Loïez

    2002-01-01

    Directors and Heads of Department from the Saclay centre of the French atomic energy commission (CEA) visited CERN in December. They are pictured here at the LHC magnet test facility in building SM18. On the left behind the visitors are the test benches where magnets are prepared for installation in String 2: the 120-metre full-scale model of an LHC cell of the regular part of the arc, which can be seen to the right. Photos 01, 02: Left to right: Marc Dejardin, Alain Givernaud, Louis Laurent, François Kircher, Antoine Masurel, Joël Feltesse, André Menez, T. Taylor, Philippe Pradelles, Bernard Sevestre, Michel Roche, Jean-Yves Gascoin, Thierry Lieven, Michel Spiro, Jean-Pierre Pervès, Yves Lemoigne, Béatrice Reder, Georges Carola, Philippe Lebrun, Yves Bourlat, Bertrand Mercier, Jean-Paul Langlois, Patrick Laurent, Didier Moulin, Xavier Vitart, Marc Serre, Jean-Louis Pierrey, Patrick Jarry, Bruno Mansoulié, Stéphane Lequien, Hervé Barbelin, Philippe Pallier, Jean-Yves Guillamot, and Norbert Sioegel.

  14. Robert Larsson : Venemaa kasutab energeetikat relvana / Robert Larsson ; interv. Mikk Salu

    Index Scriptorium Estoniae

    Larsson, Robert

    2006-01-01

    Rootsi kaitsespetsialist selgitab, mida tähendab energeetiline relv. Tema väitel on energiaressursse relvana kasutatud kõige rohkem Leedu vastu, viimasel paaril aastal on enim juhtumeid Ukraina ja Valgevene suunal

  15. 2599-IJBCS-Article-Arcadius Yves Justin A+

    African Journals Online (AJOL)

    hp

    L'évaluation du taux de reprise est de 96,35% pour les plants semés en pots contre. 94,44% pour ... sociales et environnementales (de Groot et al., 2010 ;. Ferraz et al., 2013). Dans ce cadre ...... AYJA est le porteur du projet, il a supervisé ...

  16. CIA-lt nõutakse luureinfo avalikustamist / Markus Larsson

    Index Scriptorium Estoniae

    Larsson, Markus

    2003-01-01

    USA senaator Carl Levin nõuab, et Luure Keskagentuur avalikustaks ÜRO relvastusinspektoritele edastatud salajase info Iraagi massihävitusrelvade kohta. USA Senat uurib luureinfo käsitlemist Valges Majas

  17. Yves Le Grand on matrices in optics with application to vision: Translation and critical analysis

    Directory of Open Access Journals (Sweden)

    William Frith Harris

    2013-12-01

    Full Text Available An appendix to Le Grand’s 1945 book, Optique Physiologique: Tome Premier: La Dioptrique de l’Œil et Sa Correction, briefly dealt with the application of matrices in optics.  However the appendix was omitted from the well-known English translation, Physiological Optics, which appeared in 1980.  Consequently the material is all but forgotten.  This is unfortunate in view of the importance of the dioptric power matrix and the ray transference which entered the optometricliterature many years later.  Motivated by the perception that there has not been enough care in optometry to attribute concepts appropriately this paper attempts a careful analysis of Le Grand’s thinking as reflected in his appendix.  A translation into English is provided in the appendix to this paper.  The paper opens with a summary of the basics of Gaussian and linear optics sufficient for the interpretation of Le Grand’s appendix which follows.  The paper looks more particularly at what Le Grand says in relation to the transference and the dioptric power matrix though many other issues are also touched on including the conditions under which distant objects will map to clear images on the retina and, more particularly, to clear images that are undistorted.  Detailed annotations of Le Grand’s translated appendix are provided. (S Afr Optom 2013 72(4 145-166

  18. Yves Laberge on Cross the Water Blues: African American Music in Europe (Neil A. Wynn, ed.

    Directory of Open Access Journals (Sweden)

    2010-05-01

    Full Text Available Cross the Water Blues: African American Music in Europe. Edited by Neil A. Wynn. Jackson: University Press of Mississippi, "American Made Music Series", 2007.Pp. xii + 289. ISBN 9781604735468 PaperSome scholars might wonder if there is anything new to say about the history of the blues: this overlooked book will serve as a welcome answer. A collection of fifteen new essays, mostly by renowed European scholars, Cross the Water Blues: African American Music in Europe focuses on the birth, recor...

  19. 玫瑰人生 伯爵玫瑰珠宝系列Yves Piaget Rose

    Institute of Scientific and Technical Information of China (English)

    张扬

    2012-01-01

    <正>30年,于女人,是娇媚的风华正茂;于珠宝,除了这千娇百媚之外,更是一段传奇。Piaget先生从小就对玫瑰情有独钟,上世纪70年代接触园艺后受邀成为日内瓦园艺协会的会员,后来担任协会会长,他更是大力赞助日内瓦国际新品种玫瑰竞赛。

  20. Bilder i marginalen som retorisk modus = Bilder am Rande als rhetorischer Modus / Lars Olof Larsson

    Index Scriptorium Estoniae

    Larsson, Lars Olof

    2006-01-01

    Keskajal ja varauusaja portreedel on kaunistatud ehisraamid raamatumaalis ja graafikas olulisel kohal. Näitena analüüsitakse Karl V erinevast ajast portreesid ja nende marginaalseid ehisraame ja raami dekoore, mis annavad pildile lisaväärtusena sotsiaalse ning kultuurilise tähenduse ja uue retoorika

  1. USA sõdurid hädas isetehtud pommidega / Markus Larsson

    Index Scriptorium Estoniae

    Larsson, Markus

    2004-01-01

    Vähemalt 16 USA sõdurit langes jaanuarikuus Iraagis isevalmistatud lõhkekehade ohvriks. Ameeriklased kavandavad uudseid tehnoloogilisi meetmeid, mis peaksid takistama terroristidel kaugjuhitavaid pomme käivitada

  2. Iraagi sõjas on USA sõduritele suurim oht keemia- ja biorelv / Markus Larsson

    Index Scriptorium Estoniae

    Larsson, Markus

    2003-01-01

    Kuveidis viibiv keemiarelva avastamise lahingüksus on valvel võimalikeks Iraagi ennetusrünnakuteks Kuwait City või riigis paiknevate USA sõjaväebaaside vastu. Skeem: Kaitseriietus keemiarelva vastu

  3. Bilder i marginalen som retorisk modus = Bilder am Rande als rhetorischer Modus / Lars Olof Larsson

    Index Scriptorium Estoniae

    Larsson, Lars Olof

    2006-01-01

    Keskajal ja varauusaja portreedel on kaunistatud ehisraamid raamatumaalis ja graafikas olulisel kohal. Näitena analüüsitakse Karl V erinevast ajast portreesid ja nende marginaalseid ehisraame ja raami dekoore, mis annavad pildile lisaväärtusena sotsiaalse ning kultuurilise tähenduse ja uue retoorika

  4. The algebraic difference of two random Cantor sets: The Larsson family

    NARCIS (Netherlands)

    Dekking, M.; Simon, K.; Székely, B.

    2011-01-01

    In this paper, we consider a family of random Cantor sets on the line and consider the question of whether the condition that the sum of the Hausdorff dimensions is larger than one implies the existence of interior points in the difference set of two independent copies. We give a new and complete pr

  5. Tehissüda päästis surija elu / Markus Larsson

    Index Scriptorium Estoniae

    Larsson, Markus

    2001-01-01

    Esimese täielikult inimkehasse opereeritava alalise kunstliku plastmassist ja titaanist asendussüdame sai mees, kelle nime ja päritolu ei avalikustata, üleeile Kentuky osariigis Louisvilles Jewish Hospitalis

  6. Tehissüda päästis surija elu / Markus Larsson

    Index Scriptorium Estoniae

    Larsson, Markus

    2001-01-01

    Esimese täielikult inimkehasse opereeritava alalise kunstliku plastmassist ja titaanist asendussüdame sai mees, kelle nime ja päritolu ei avalikustata, üleeile Kentuky osariigis Louisvilles Jewish Hospitalis

  7. Karl Gustaf Torsten Sjögren and Sjögren-Larsson syndrome

    OpenAIRE

    2011-01-01

    Karl Gustaf Torsten Sjögren (1896-1974) a Swedish psychiatrist and geneticist, was a pioneer of modern Swedish psychiatry. Sjögren studied medicine at the University of Uppsala. From 1932 to 1935, he was Head Physician and Director of Lillehagen Hospital in Gothenburg, and between 1935- 1945, he was physician-in-chief at the psychiatric department of Sahlgrenska Hospital in Gothenburg. Sjögren was professor of psychiatry at Karolinska Institutet from 1945 to 1961 and was elected to the Royal...

  8. Homoabielu mõjutas USA valikut rohkem kui Iraak / Markus Larsson

    Index Scriptorium Estoniae

    Larsson, Markus

    2004-01-01

    Autor iseloomustab ameeriklaste väärtushinnanguid ning seostab neid presidendivalimiste tulemustega, mis tema sõnul kinnitavad väidet, et Ameerika Ühendriikides püsivad kesksel kohal moraalsed väärtused. Lisa: Abielu- ja aborditüli ei lõhesta riiki

  9. Igapäevased hirmud kõigutavad usaldust toidu vastu / Markus Larsson

    Index Scriptorium Estoniae

    Larsson, Markus

    2003-01-01

    Harvardi Ülikooli riskianalüüsikeskuse juhataja David Ropeik ja toksikoloog George Gray kirjutasid koos raamatu "Risk: praktilisi juhiseid tõeliselt ohtlikest ja tõeliselt ohututest asjadest teie ümber"

  10. USA paneb välisabi kaitsma oma huve maailmas / Markus Larsson

    Index Scriptorium Estoniae

    Larsson, Markus

    2003-01-01

    USA valitsuse raporti kohaselt tuleb riigi välisabiprogramme hakata kohandama nii, et need oleksid suunatud USA rahvuslike huvide kaitsele ning vabaduse ja julgeoleku laiendamisele kogu maailmas. USAID juhataja Andrew Natsiose seisukohti

  11. Anne Dulphy et Yves Léonard (dir.), De la dictature à la démocratie

    OpenAIRE

    González Calleja, Eduardo

    2010-01-01

    Como es bien sabido, las transiciones a la democracia en Portugal y España, ubicadas en los prolegómenos de la «tercera ola» democratizadora estudiada por Samuel P. Huntington, que se amplió a América Latina en los años 1980 y a Europa del Este a inicios de los años 1990, han generado desde su misma culminación una vasta publicística de naturaleza fundamentalmente política, algunos de cuyos autores más distinguidos por su significativo aporte teórico y por su voluntad comparativa son Juan J. ...

  12. Bridging the ideological space: a cross-national analysis of the distance of party switching / Ruth Dassonneville, Yves Dejaeghere

    Index Scriptorium Estoniae

    Dassonneville, Ruth

    2014-01-01

    Artikkel keskendub selget eelistust mitteomavatele (volatiilsetele) valijatele, küsides, kas valimistulemuste ettearvamatus sõltub rohkem haritud valijate hästi läbimõeldud valikutest või on tulemus mitte nii haritud ja selget eelistust mitteomavate valijate kätes. Aluseks. valimissüsteemide võrdlevuuring, sh Eesti 2011. aasta valimiste kohta.

  13. Bridging the ideological space: a cross-national analysis of the distance of party switching / Ruth Dassonneville, Yves Dejaeghere

    Index Scriptorium Estoniae

    Dassonneville, Ruth

    2014-01-01

    Artikkel keskendub selget eelistust mitteomavatele (volatiilsetele) valijatele, küsides, kas valimistulemuste ettearvamatus sõltub rohkem haritud valijate hästi läbimõeldud valikutest või on tulemus mitte nii haritud ja selget eelistust mitteomavate valijate kätes. Aluseks. valimissüsteemide võrdlevuuring, sh Eesti 2011. aasta valimiste kohta.

  14. Mees, kes vihkas sotsiaalabisüsteemi / Oudekki Loone

    Index Scriptorium Estoniae

    Loone, Oudekki, 1979-

    2010-01-01

    Arvustus: Larsson, Stieg. Lohetätoveeringuga tüdruk. Tallinn: Varrak, 2009 ; Larsson, Stieg. Tüdruk, kes mängis tulega. Tallinn: Varrak, 2009 ; Larsson, Stieg. Purustatud õhuloss. Tallinn : Varrak, 2010

  15. Meeting of Directors and Heads of Department from CEA-Saclay, France

    CERN Multimedia

    Patrice Loïez

    2002-01-01

    Y. Lemoigne (left) in discussion with M. Spiro during the visit to CERN of Directors and Heads of Department from the Saclay centre of the French atomic energy commision (CEA) in December. P. Jarry looks on.

  16. We/You Can Tell Talk from Matter: A Conversation with Håkan Larsson and Mikael Quennerstedt

    Science.gov (United States)

    Evans, John; Davies, Brian; Rich, Emma

    2014-01-01

    How we go about conceptualising and articulating relationships between the body as "matter" and its "mattering" in and by culture, is a critical issue for educational researchers, perhaps especially so for those in Physical Education, Health and sport (PEHS). This paper engages such issue via conversation with ideas presented…

  17. Kuidas illegaalina USA-sse pääseda? Rio Grande ja Arizona tapvad kõrbed / Markus Larsson

    Index Scriptorium Estoniae

    Larsson, Markus

    2004-01-01

    Ameerika Ühendriikide ja Mehhiko raskesti kontrollitaval piiril peavad valvet vabatahtlikud ameeriklastest farmiomanikud ning immigratsiooni piiramist nõudvad kodanikud, kuid on ka neid vabatahtlikke, kelle eesmärk on aidata kõrbes hätta sattunud illegaale

  18. Kuidas illegaalina USA-sse pääseda? Rio Grande ja Arizona tapvad kõrbed / Markus Larsson

    Index Scriptorium Estoniae

    Larsson, Markus

    2004-01-01

    Ameerika Ühendriikide ja Mehhiko raskesti kontrollitaval piiril peavad valvet vabatahtlikud ameeriklastest farmiomanikud ning immigratsiooni piiramist nõudvad kodanikud, kuid on ka neid vabatahtlikke, kelle eesmärk on aidata kõrbes hätta sattunud illegaale

  19. USA poliitikud ei söanda keelata ründerelvade müüki / Markus Larsson

    Index Scriptorium Estoniae

    Larsson, Markus

    2004-01-01

    USA-s lõppes teatud tüüpi poolautomaat-ründerelvade müügi keeld. Kongress ei ole presidendile esitanud keelu jätkumist käsitlevat seaduseelnõu. Endise presidendi Bill Clintoni hinnangul kaotasid demokraadid ründerelvade keelu pooldamise tõttu Kongressis vähemalt 20 kohta. Lisa: Ründerelvade osakaal väike

  20. Yves Henigfeld, La céramique à Strasbourg de la fin du Xe au début du XVIIe siècle

    Directory of Open Access Journals (Sweden)

    Philippe Husi

    2008-04-01

    Full Text Available Les publications de synthèse dans le domaine de la céramologie médiévale et moderne sont trop rares pour ne pas être soulignées, surtout lorsqu’elles sont de qualité, comme celle dont je me propose ici de faire un rapide compte rendu. Cet ouvrage correspond à la publication d’une thèse, exercice périlleux, puisqu’il ne doit ni omettre d’apporter les preuves d’un discours construit, ni noyer le lecteur dans les dédalles d’une recherche pointue et indigeste. A mon sens, l’auteur a réussi ce dif...

  1. Gonzalez-Quijano Yves, Arabités numériques, le printemps du web arabe, Paris, Sindbad, 2012, 187p.

    Directory of Open Access Journals (Sweden)

    Catherine Miller

    2013-07-01

    Full Text Available Ce petit ouvrage paru en 2012 revient dans un style alerte sur le rôle qu’ont joué les réseaux sociaux comme catalyseurs de la révolte et de la mobilisation pendant le « Printemps arabe » de 2011. L’auteur est un spécialiste des médias arabes qu’il ausculte depuis des années et dont il livre de nombreuses analyses à travers son blog Culture et politiques arabes (http// :cpa.hypothèses.org. Un des grands mérites de cet ouvrage est de dépasser l’actualité immédiate pour fournir un panorama syn...

  2. Teisitimõtlejast uurija: seagripivastane vaktsineerimine on ülemaailmne vandenõu / Yves Delatte ; intervjueerinud Priit Hõbemägi

    Index Scriptorium Estoniae

    Delatte, Yves

    2009-01-01

    Bioloog ja uurija väidab, et H1N1 viirust levitati maailmas B-hepatiidi vaktsiini kaudu ning märgib, et pole ühtki uuringut selle kohta, mis juhtub siis, kui uut gripivaktsiini süstitakse nt. lapsele, kes on juba vaktsineeritud lastehalvatuse vastu

  3. Tarih Nasıl Yapılır - François Cadiou, Clarisse Coulomb, Anne Lemonde ve Yves Santamaria

    Directory of Open Access Journals (Sweden)

    Mustafa Alican

    2013-10-01

    Full Text Available Tarih Nasıl Yapılır, dört Fransız akademisyen-tarihçi tarafından kaleme alınmış olan bir metindir. Bir tür "tarihin tarihi" olma niteliğini taşımakta olup tarihsel olanın niteliklerini sorgulamaktadır. Tarihsel olanın niteliklerini saptamak gibi netameli bir çabaya karşılık gelen söz konusu metin, antikçağdan günümüze uzanan süreçte tarih disiplini ile ilgili pratikleri geniş bir perspektif üzerinden ele almaktadır.

  4. Commentary: ADHD and Social Disadvantage: An Inconvenient Truth?--A Reflection on Russell et al. (2014) and Larsson et al. (2014)

    Science.gov (United States)

    Nigg, Joel T.; Craver, Lindsay

    2014-01-01

    In the 1950's, many experts believed hyperkinesis was a neurotic reaction to inner conflicts arising from early family experiences. In the 1990's, many experts believed ADHD to be "genetic" (without a mechanistic explanation of what that meant). Both views appear naïve today in a scientific world grappling with the complexity…

  5. Eesti lasteaed - tänavune laureaat / Muusa Ericsson, Silvi Somp, Riina-Maj Larsson-Mänd ; küsitl. Mai Raud-Pähn

    Index Scriptorium Estoniae

    Ericsson, Muusa

    1996-01-01

    EV 78. aastapäeval, 24. veebruaril 1996 Stockholmi Eesti Majas korraldatud Rootsi Eestlaste Liidu vastuvõtul tehti teatavaks REL Kultuuriauhinna kolleegiumi otsus anda 1996. a. auhind Eesti Lasteaiale

  6. Qasimia gen. nov., an early Marattia-like fern from the Permian of Saudi Arabia

    NARCIS (Netherlands)

    Hill, C.R.; Wagner, R.H.; El-Khayal, A. A.

    1985-01-01

    The marattialean fern Qasimia schyfsmae (Lemoigne) gen. et comb. nov. is described from the Late Permian plant bed at Unayzah in central Saudi Arabia. Although no organic matter is preserved, impregnation of the compressions by iron minerals at an early stage of diagenesis has partly mineralised the

  7. Disease: H00162 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00162 Sjogren-Larsson syndrome Sjogren-Larsson syndrome is an autosomal recessive ...224] [KO:K00128] ICD-10: E71.3 MeSH: D016111 OMIM: 270200 PMID:17254005 Gordon N Sjogren-Larsson syndrome. D...ev Med Child Neurol 49:152-4 (2007) PMID:16996289 Rizzo WB Sjogren-Larsson syndrome: molecular genetics and ...tab 90:1-9 (2007) PMID:15931689 Rizzo WB, Carney G Sjogren-Larsson syndrome: diversity of mutations and poly

  8. Turister på krimibølgen

    DEFF Research Database (Denmark)

    Grodal, Torben Kragh

    2009-01-01

    Indlægget karakteriserer hvilke fascinationer og behov der tilfredsstilles i kriminalfiktion, med særlig henblik på Stieg Larsson-romaner og filmatiseringer Udgivelsesdato: Novenber......Indlægget karakteriserer hvilke fascinationer og behov der tilfredsstilles i kriminalfiktion, med særlig henblik på Stieg Larsson-romaner og filmatiseringer Udgivelsesdato: Novenber...

  9. Artificial Intelligence (Al) Center of Excellence at the University of Pennsylvania

    Science.gov (United States)

    1995-07-01

    Yves Schabes "Computational Feasibility of Assistant Professor, University of Some Constrained Grammatical Nebraska...proposed FLAT MMF is used. Parsing with Lexicalized Tree Adjoining Grammar Yves Schabes Aravind K. Joshi MS-CIS-90-11 LINC LAB 164 Most...A Lexicalized Tree Adjoining Grammar for English Anne Abeille, Kathleen Bishop, Sharon Cote, and Yves Schabes MS-CIS-90-24 LINC LAB 170 This

  10. Moeuudised

    Index Scriptorium Estoniae

    1998-01-01

    Prantsuse moemaja Chloe peadisainer Stella McCartney aitas loomakaitseorganisatsioonil PETA teha dokumentaalfilmi, milles paljastatakse karusloomafarmide telgitaguseid. Chloe supelkostüümist, mida soovitatakse eeskujuks võtta endale bikiinide heegeldamisel. Yves Saint Laurenti moemaja korraldab gigantse moeshow jalgpallistaadionil, kus algab jalgpalli MM. Yves Saint Laurent on kavandanud MMi korraldajate-asjameeste kostüümid

  11. Beuret Jean-Eudes, Anne Cadoret, 2010. Gérer ensemble les territoires, Vers une démocratie participative. Editions Charles Léopold Mayer, Fondation de France. Préface de Francis Charhon, postface de Pierre-Yves Guihéneuf et Loïc Blondiaux, 228 p.

    Directory of Open Access Journals (Sweden)

    Marion Amalric

    2011-06-01

    Full Text Available L’ouvrage de Jean-Eudes Beuret et Anne Cadoret, Gérer ensemble les territoires, Vers une démocratie participative propose un regard à la fois pratique et conceptuel sur les démarches participatives dans le domaine très large de la gestion de l’environnement, de l’aménagement et du développement durable. Il répond à une proposition de la Fondation de France d’analyser dans leur ensemble les quelque 300 projets qui ont été financés dans le cadre de son appel à projet « Ensemble pour gérer le te...

  12. Evaluation of the protective efficacy of immunoglobulin Y (IgY ...

    African Journals Online (AJOL)

    user

    2012-09-06

    Sep 6, 2012 ... Key words: Snake venom, Walterinnesia aegyptia, immunoglobulins Y, protective efficacy, caprylic acid. ... protection of the embryo against the infections (Larsson ..... viral IgY antibodies from yolks of immunized hens.

  13. The CMS team celebrates the arrival of the "Tube". From left to right, sitting: Blanca Perea Solano, Jeannine Muffat-Joly, Ariella Cattai (Tracker Technical Coordinator). Standing: Georges Roiron, Hans Postema, Eric Albert, Paolo Petagna, Arvid Larsson, Nuno Bernardino Rodrigues, Enzo Carrone, Jack Hill.

    CERN Multimedia

    Maximilien Brice

    2004-01-01

    CMS: Aerospace goes underground : gleaming aluminium on the outside and carbon black on the inside, as long as a sedan and taller than a man, a strange hollow cylinder arrived at CERN by truck August 26.

  14. Häid tagajärgi Helsingist / Taive Abner

    Index Scriptorium Estoniae

    Abner, Taive

    2012-01-01

    Helsingi International Horse Show raames toimunud Lääne-Euroopa liiga takistussõidu MK etapi võitis prantslane Roger Yves Bost ning Helsingis erinevatel takistussõidu tasemetel võistelnud Eesti ratsutajate tulemustest

  15. Mõjukad eurooplased / Aavo Kokk

    Index Scriptorium Estoniae

    Kokk, Aavo, 1964-

    2001-01-01

    Portree inimestest, kes mõjutavad Ida-Euroopa äri ja poliitikat: Frederick Kempe, Jean Lumierre, Vagit Alekperov, Moritz Gerke, Henri Giraud, Jean-Yves le Gall, Malay Mukherjee, Herbert Stepic, Pedrag Max Vranic, Maria Wisniewska

  16. Plaadid / Margus Kiis

    Index Scriptorium Estoniae

    Kiis, Margus

    2002-01-01

    Uutest plaatidest Nightlight Dou "La Fiesta Del Sol", Yves Montand "Ses Plus Grands Succes", Natalia Oreiro "Tu veneno", Daishin Kashimoto "Passionata", Mike Oldfield "Tres Lunas", Ali G Indiahouse "Da Soundtrack", Ronan Keating "Destination", Roger Waters "Flickering Flame"

  17. Dragotsennaja osen / Tatjana Barmakova

    Index Scriptorium Estoniae

    Barmakova, Tatjana

    2004-01-01

    Moefirmade Dior, Yves Saint Laurent (jumestuskunstnik Linda Cantello), Guerlain (kunstnik Olivier Echaudemaison), Shiseido (kunstnik Tom Pecheux) meigikollektsioonidest. Diori, Kenzo ja Thierry Mugleri uutest parfüümidest. "Kenzoairi" parfüümipudeli disainis klaasikunstnik Laura de Santillana

  18. Plaadid / Margus Kiis

    Index Scriptorium Estoniae

    Kiis, Margus

    2002-01-01

    Uutest plaatidest Nightlight Dou "La Fiesta Del Sol", Yves Montand "Ses Plus Grands Succes", Natalia Oreiro "Tu veneno", Daishin Kashimoto "Passionata", Mike Oldfield "Tres Lunas", Ali G Indiahouse "Da Soundtrack", Ronan Keating "Destination", Roger Waters "Flickering Flame"

  19. Back from Sestriere

    CERN Multimedia

    2006-01-01

    Jean-Yves Le Meur during the Special Slalom at the Paralympic Winter Games on 19 March. (Photo credit: G. Place and B. Loyseau) CERN's Olympian, Jean-Yves Le Meur (IT Department), is back from Sestriere after competing in the Paralympic Winter Games in the sitting skiing competition. Ranked 14th after his first run in the Special Slalom, Jean-Yves had an excellent second run which brought him right up the field. He eventually finished ninth, 11 seconds off the gold medal place. In the Giant Slalom, he unfortunately fell in the final gates of his second run, having reached 10th position in his first run. With about 50 top athletes from all the competing nations contesting each event, the competition was stiff, and our warmest congratulations go to Jean-Yves for his participation and great performance!

  20. Häid tagajärgi Helsingist / Taive Abner

    Index Scriptorium Estoniae

    Abner, Taive

    2012-01-01

    Helsingi International Horse Show raames toimunud Lääne-Euroopa liiga takistussõidu MK etapi võitis prantslane Roger Yves Bost ning Helsingis erinevatel takistussõidu tasemetel võistelnud Eesti ratsutajate tulemustest

  1. Mõjukad eurooplased / Aavo Kokk

    Index Scriptorium Estoniae

    Kokk, Aavo, 1964-

    2001-01-01

    Portree inimestest, kes mõjutavad Ida-Euroopa äri ja poliitikat: Frederick Kempe, Jean Lumierre, Vagit Alekperov, Moritz Gerke, Henri Giraud, Jean-Yves le Gall, Malay Mukherjee, Herbert Stepic, Pedrag Max Vranic, Maria Wisniewska

  2. Dragotsennaja osen / Tatjana Barmakova

    Index Scriptorium Estoniae

    Barmakova, Tatjana

    2004-01-01

    Moefirmade Dior, Yves Saint Laurent (jumestuskunstnik Linda Cantello), Guerlain (kunstnik Olivier Echaudemaison), Shiseido (kunstnik Tom Pecheux) meigikollektsioonidest. Diori, Kenzo ja Thierry Mugleri uutest parfüümidest. "Kenzoairi" parfüümipudeli disainis klaasikunstnik Laura de Santillana

  3. Mistreatment of the Wounded, Sick and Shipwrecked By The International Committee of the Red Cross Study On Customary International Humanitarian Law

    Science.gov (United States)

    2008-01-31

    proposed Rule 111: Duty to Protect the Wounded, the Sick, and the Shipwrecked). 16 Dr. Yves Sandoz recognizes, in his forward to the ICRC Study, that... Sandoz , Christophe Swinarski & Bruno Zimmerman eds., 1987) [hereinafter AP COMMENTARY]. 61 has built into its proposed rule a notion of military...perceived utility of the ICRC Study). 525 Dr. Yves Sandoz recognizes, in his forward to the ICRC Study, that “this study will have achieved its goal

  4. On Bonnefoy

    OpenAIRE

    Mansfield, Charlie

    1993-01-01

    Book review of English translation of French poetry by Yves Bonnefoy With these narrative artefacts, fragmented and unfinished, Yves Bonnefoy begins to show us a world without conclusion. His act of defiance towards the narrative pressures inherent in both the French and English languages sets up a tension, even a violence in this book of poems. Ostensibly, the volume is about a female lover, Douve. Douve, though, is the French word for a moat, that uncrossable body which separates us fro...

  5. Two Film Adaptations of Larsson’s novel The Girl with the Dragon Tattoo : A Semiotic and Audience Reception Study

    OpenAIRE

    Casprov, Alexandra Genţiana

    2012-01-01

    Stieg Larsson has reached vast audiences with his popular, page-turning crime novels, the Millennium Series. The series tells a story not just for fictional purposes, but to draw attention to what people did not see about the society that Larsson lived in. In 2009, local actors starred in a film adaptation of Larsson’s first novel, which went beyond the Swedish public. In December 2011 an English-language remake based on the same bestseller was released, starring famous Hollywood actors. Cons...

  6. Commissaire Moulin visits CERN

    CERN Multimedia

    CERN Bulletin

    2014-01-01

    The French actor and film-maker Yves Rénier was shown around the Laboratory on Friday 6 June by friends at CERN.   Yves Rénier at LEIR. (Photo: Ludwig Pregernig) A keen diver and star of the long-running French television police drama Commissaire Moulin, Yves Rénier took advantage of a stopover in Geneva on his way to the Red Sea to meet up with his friends from the CERN Diving Club, who were only too pleased to take him on a tour of the Laboratory. In the morning, Yves Rénier visited the CERN Control Centre (CCC), Linac2 and LEIR. After lunch at the brasserie in Restaurant No. 2, the actor continued his tour with the CERN Computer Centre, the SM18 superconducting magnet test facility, and lastly the ATLAS experiment. “Thank you so much for showing me around and introducing me to a world I knew so little about,” confided Yves Rénier. “It’s fascinating to see so many scientists of different cultures,...

  7. Mormoonid võõrustavad olümpiat / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2002-01-01

    Taliolümpiamängude linn Salt Lake City on pooleteise sajandiga kasvanud väikesest mormoonide asulast kümne miljoni mormooni maailmapealinnaks. Kaart : Utah osariik. Lisa : Markus Larsson. Toretsev, salapärane ja võimas usulahk

  8. Tøser & Twilight – for romantisk til at være gys?

    DEFF Research Database (Denmark)

    Schubart, Rikke

    2012-01-01

    Diskussion af ny antologi og hvorfor tøser elsker Twilight – bøgerne, filmene og fan-sites’ene på nettet – mens mænd nedgør fænomenet. Antologi: Interdiscipliary Approaches to Twilight: Studies in Fiction, Media, and a Contemporary Cultural Experience, redigeret af Mariah Larsson og Ann Steiner. ...

  9. 2008. aasta menukaimad / Udo Uibo

    Index Scriptorium Estoniae

    Uibo, Udo, 1956-

    2009-01-01

    2008. aasta raamatumüügi tulemustest, mulluste menukamate kirjanike nimestikust, mis põhineb USA, Suurbritannia, Prantsusmaa, Saksamaa, Itaalia, Hollandi, Hiina, Hispaania ja Rootsi igakuistel ilukirjanduslike bestsellerite edetabelitel. Esikümnesse kuuluvad: Khaled Hossein, Stieg Larsson, Ken Follett, Stephenie Meyer, Muriel Barbery, Carlos Ruiz Zafón, Anna Gavalda, John Grisham, J. K. Rowling, Henning Mankell

  10. Millennium

    DEFF Research Database (Denmark)

    forfatterskaber, fx: Helle Helle, Kirsten Hammann, Jonas Hassen Khemiri, Stieg Larsson, Kari Hotakainen, Monika Fagerholm, Øyvind Rimbereid, Karl Ove Knausgård, Sjón, Gyrðir Elíasson, Jóanes Nielsen, Tóroddur Poulsen og Hans Jakob Helms. Bogen er forsynet med en indledning, der kort opsummerer indholdet af de...

  11. Mord og metafysik

    DEFF Research Database (Denmark)

    Hansen, Kim Toft

    2012-01-01

    overnaturlige. Mord og metafysik inddrager titler fra forfatterskaber som Arne Dahl, Elsebeth Egholm, Stieg Larsson, Håkan Nesser, Sara Blædel, Gunnar Staalesen, Tom Egeland, Camilla Läckberg, Anne Holt, Peter Høeg, Johan Theorin og mange flere. Desuden suppleres disse af tv-serier som Rejseholdet, Livvagterne...

  12. Mord og metafysik

    DEFF Research Database (Denmark)

    Hansen, Kim Toft

    overnaturlige. Mord og metafysik inddrager titler fra forfatterskaber som Arne Dahl, Elsebeth Egholm, Stieg Larsson, Håkan Nesser, Sara Blædel, Gunnar Staalesen, Tom Egeland, Camilla Läckberg, Anne Holt, Peter Høeg, Johan Theorin og mange flere. Desuden suppleres disse af tv-serier som Rejseholdet, Livvagterne...

  13. Mormoonid võõrustavad olümpiat / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2002-01-01

    Taliolümpiamängude linn Salt Lake City on pooleteise sajandiga kasvanud väikesest mormoonide asulast kümne miljoni mormooni maailmapealinnaks. Kaart : Utah osariik. Lisa : Markus Larsson. Toretsev, salapärane ja võimas usulahk

  14. Värsked sõnumid energiasõja kaevikutest / Argo Ideon

    Index Scriptorium Estoniae

    Ideon, Argo, 1966-

    2006-01-01

    Väljavõtteid 19. juulil Hans Rebase Euroopa Instituudi korraldatud debatist Euroopa Liidu ja Venemaa energiasuhete üle, kus võtsid sõna Keith C. Smith, Andris Kesteris, Robert Larsson, Marko Mihkelson, Alan Riley ja Andrei Belõi

  15. 2008. aasta menukaimad / Udo Uibo

    Index Scriptorium Estoniae

    Uibo, Udo, 1956-

    2009-01-01

    2008. aasta raamatumüügi tulemustest, mulluste menukamate kirjanike nimestikust, mis põhineb USA, Suurbritannia, Prantsusmaa, Saksamaa, Itaalia, Hollandi, Hiina, Hispaania ja Rootsi igakuistel ilukirjanduslike bestsellerite edetabelitel. Esikümnesse kuuluvad: Khaled Hossein, Stieg Larsson, Ken Follett, Stephenie Meyer, Muriel Barbery, Carlos Ruiz Zafón, Anna Gavalda, John Grisham, J. K. Rowling, Henning Mankell

  16. Diagnosis and treatment of pancreatic somatostatinoma:a case report

    Institute of Scientific and Technical Information of China (English)

    ZHANG Zheng-yun; LI Hong-wei; ZHOU Guang-wen; ZHANG Rui; WANG Lin; SHEN Chuan; YAN Ji-qi; CHEN Yong-jun; LI Qin-yu; YANG Wei-ping; PENG Cheng-hong

    2008-01-01

    @@ Pancreatic somatostatinoma represents a rare group of neuroendocrine tumors,which was first reported by Ganda and Larsson in 1977.Less than 50 cases have been reported to the present.We treated a case of pancreatic somatostatinoma at our hospital.

  17. International Conference on Defects-Recognition, Imaging and Physics in Semiconductors (13th), held at Wheeling, West Virginia, on 13-17 September 2009

    Science.gov (United States)

    2010-06-01

    improve tribological, biological, corrosion, or aesthetic properties into a component. The choice of the substrate material and type of coating for...Engineering. 19 (2-6) (2002), pp. 43-50. 2. S. Hogmark, S. Jacobson. and M. Larsson, Wear. 246 (2000). pp. 20-33. 3. M. Schaldach. Electrotherapy of the

  18. Regularized Reconstruction of Dynamic Contrast-Enhanced MR Images for Evaluation of Breast Lesions

    Science.gov (United States)

    2011-01-01

    vol. 23, no. 1, pp. 87–91, Jan. 2006. [12] M. V. Knopp, E. Weiss, H. P. Sinn, J. Mattern, H. Junkermann, J. Radeleff, A. Magener, G. Brix , S. Delorme...13] P. S. Tofts, G. Brix , D. L. Buckley, J. L. Evelhoch, E. Henderson, M. V. Knopp, H. B. Larsson, T. Y. Lee, N. A. Mayr, G. J. Parker, R. E. Port

  19. ARL Summer Student Research Symposium. Volume 1: Select Papers

    Science.gov (United States)

    2012-08-01

    Journal of Electromyography and Kinesiology 2011, 21, 25–32. 6. Gerdle, B.; Larsson, B.; Karlsson, S. Criterion Validation of Surface EMG...Variables as Fatigue Indicators using Peak Torque: a Study of Repetitive Maximum Isokinetic Knee Extensions. Journal of Electromyography and Kinesiology

  20. PIAGET伯爵 自花间绽放的灵动高级珠宝

    Institute of Scientific and Technical Information of China (English)

    2014-01-01

    <正>向伊英·伯爵YVES PIAGET先生对玫瑰的热情致意对Piaget伯爵而言,玫瑰是一个幸运图腾。Yves Piaget玫瑰有着近似牡丹的外形——它们充满激情、骑槐诱人、光彩夺目。当花朵遇上珠宝一切都缘起于一名男子与一株花

  1. What's new @CERN ?

    CERN Multimedia

    CERN video productions

    2011-01-01

    A very busy Summer has just come to an end, with the LHC’s first major results being announced at the Summer physics conferences. It is these results that takes centre stage in this programme with our guests Monica Pepe-Altarelli , Yves Sirois et Christophe Clement.

  2. 1254-IJBCS-Article-Moussa Gibigaye

    African Journals Online (AJOL)

    hp

    Malanville au nord du Bénin. Moussa GIBIGAYE 1*, Yves Antoine TOHOZIN 1 et Yacouba SANON 2. 1Département de Géographie et Aménagement du Territoire /FLASH/UAC, ... *Auteur correspondant, E-mail : Moussa_gibigaye@yahoo.fr.

  3. Tectonic Scents – Elocutions on the Opium of Maison de Verre

    DEFF Research Database (Denmark)

    Fisker, Anna Marie; Hvejsel, Marie Frier; Tvedebrink, Tenna Doktor Olsen

    2017-01-01

    , hold a sensuous elocution that should be positioned in future architectural research, we ask ourselves? In the essay we pursue this sensuous potential through a semiotic study of the house and the commercial by David Lynch for Yves Saint Laurent’s controversial Opium fragrance filmed in the illusory...

  4. Information Manpower Forecasting. Papers Presented at the FID/ET Seminar (Espoo, Finland, August 24-27, 1988).

    Science.gov (United States)

    Dosa, Marta L., Ed.; Froehlich, Thomas J., Ed.

    This collection contains 20 papers written by educators, administrators and information scientists who had conducted manpower surveys in the library and information fields: (1) "Background and Evolution of Educational Planning and Forecasting for Information Manpower" (Yves Courrier); (2) "Indicators for the Emerging Information…

  5. Millennium Dome publikupuuduses

    Index Scriptorium Estoniae

    2000-01-01

    Londoni Millennium Dome toob iga nädal umbes 7 miljonit krooni kahjumit. Valitsusel on plaanis laenata Dome'ile 60 miljonit naela. Jennie Page'i asemele kutsuti direktoriks Pariisi Eurodisney juht Pierre-Yves Gerbeau. Inglise riiklike muuseumide ja kunstigaleriide tasuta külastatavaks muutmine alates aastast 2002 jääb ära.

  6. Drone Warfare: Is the United States Violating the Law of Armed Conflict

    Science.gov (United States)

    2011-02-16

    of the Red Cross Commentary on the Additional Protocols of 8 June 1977 to the Geneva Conventions of 12 August 1949, 515 (Y. Sandoz , C. Swinarski, B...Additional to the Geneva Conventions of 12 August 1949, 8 June 1977, ed. Yves Sandoz , Christophe Swinarski, and Bruno Zimmermann (International

  7. C-H and H-H Activation in Transition Metal Complexes and on Surfaces.

    Science.gov (United States)

    1983-01-01

    Jane Jorgensen and Elisabeth Fields, and the typing by Eleanor Stolz. The permanent address of Jean-Yves Saillard is at the Laboratoire de...Soc. 1980, 102, 981-986. (s) Brookhart, M.; Lamanna, W.; Humphrey, M. B. J. Am. Chem. Soc. 1982, 104, 2117-2126. (t) Schultz, A. J.; Teller , R. G

  8. Full speed ahead!

    CERN Document Server

    Anaïs Schaeffer

    2014-01-01

    When he’s not working at CERN, Jean-Yves Le Meur is a top-level skier. Fresh from the Winter Paralympics in Sochi and the French disability snowsport championship, he has agreed to answer a few questions.   Jean-Yves tackles a giant slalom. Image: @FFH. Few athletes can boast of having participated in the Olympic or Paralympic Games even once in their sporting career, let alone four times... But Jean-Yves Le Meur, a member of both CERN’s IT-CIS Group and the French disabled ski team, tells me modestly during our interview that this is what he has achieved. While the skier might act like it’s no big deal, it leaves me, amateur sportsperson that I am, dumbfounded. A few weeks ago in Sochi, the sun shining a little too brightly, Jean-Yves left his fourth Paralympics with the same enthusiasm he had for the previous three, and the same bitter taste in his mouth: “Just like in the 2010 Winter Paralympics in Vancouver, I failed to finish the sitting slalom, d...

  9. Going for gold!

    CERN Multimedia

    2006-01-01

    Jean-Yves Le Meur of CERN's IT Department will be competing in the Sitting Alpine Ski events at the upcoming Paralympic Winter Games. After one of his arms was left paralysed by shoulder surgery last year, simply taking part represents an extraordinary achievement. Jean-Yves Le Meur competing in the European competition, which won him his ticket for the Paralympic Games in Turin... ...and on top of the podium after winning a Special Slalom European Cup. You've seen 'The Incredibles'at the movies? Now meet Mr. Incredible in real life! From 10 to 19 March in Turin, Jean-Yves Le Meur (IT-UDS) will take part in his second Paralympic Winter Games, after Salt Lake City in 2002. He will be one of the 10 disabled sports champions selected to represent France in the Alpine ski events, competing in the sitting categories of the Giant Slalom and Special Slalom. But this time around, Jean-Yves needed even more determination than for any of his previous competitions, as a s...

  10. 75 FR 9028 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G

    Science.gov (United States)

    2010-02-26

    ... ALEXANDER BALDWIN MARIA D BALFOUR ALEXANDER DAVID BANERJEE SOUMYA BAUMBERGER YVES BELL CHARLES HENRY BERKES... CAMPBELL VIRGINIA ELLEN CARR RODERICK JAMES CHAN CHARLES TSUN-YAN CHAN CLARA KIT YEE CHAN JOYCE YUEN WAH... VIJAYALAXMI GAGNON JAMES ERNEST GAPE DEREK GREGORY GARDNER GREGORY JOHN GARRIDO LILIA GUADALUPE GAVIN...

  11. Unustatud katakombid / Claudia Haj Ali

    Index Scriptorium Estoniae

    Haj Ali, Claudia

    1999-01-01

    Arheoloog Jean-Yves Empereur leidis Egiptuse Aleksandria linna lähedal asuvasse kaljusse rajatud katakombid, mis on osa hellenistlikul perioodil rajatud ning pikka aega unustuse hõlmas olnud surnute linnast. Leidude seas on kipsist Meduusa pea nind leide Rooma perioodist.

  12. Matrjoshki ot kutjur

    Index Scriptorium Estoniae

    2008-01-01

    Vene moeajakirja Vogue kümnendaks juubeliks joonistasid tuntud moekunstnikud kogu maailmast matrjoshkade eskiise. Eskiiside järgi maalisid vene meistrid poolemeetrised nukud. Nii sai ajakiri kingituseks Yves Saint Laurent'i, Versace, Prada, Dolce&Gabbana, Oscar de la Renta, Judashkini, Simatshovi ja paljude teiste matrjoshkad

  13. Franchising jako způsob vstupu na trh

    OpenAIRE

    Vajdečková, Barbora

    2011-01-01

    This bachelor thesis deals with franchising as the possible entry method to the market. The first part explains theoretical aspects of franchising. In the second chapter the position of franchising on the Czech market is analyzed. The last chapter illustrates the use of franchising in a successful cosmetics company Yves Rocher.

  14. Matrjoshki ot kutjur

    Index Scriptorium Estoniae

    2008-01-01

    Vene moeajakirja Vogue kümnendaks juubeliks joonistasid tuntud moekunstnikud kogu maailmast matrjoshkade eskiise. Eskiiside järgi maalisid vene meistrid poolemeetrised nukud. Nii sai ajakiri kingituseks Yves Saint Laurent'i, Versace, Prada, Dolce&Gabbana, Oscar de la Renta, Judashkini, Simatshovi ja paljude teiste matrjoshkad

  15. Collective flow in relativistic heavy-ion collisions

    Indian Academy of Sciences (India)

    R S Bhalerao

    2003-11-01

    A brief introduction is given to the field of collective flow, currently being investigated experimentally at the Relativistic Heavy-Ion Collider, Brookhaven National Laboratory. It is followed by an outline of the work that I have been doing in this field, in collaboration with Nicolas Borghini and Jean-Yves Ollitrault.

  16. Karl Lagerfeld obidelsja

    Index Scriptorium Estoniae

    2006-01-01

    Moekunstnik Karl Lagerfeld kaebas kohtusse raamatu "The Beautiful Fall : Fashion, Genius and Glorious Excess in 1970s Paris" autori Alicia Drake'i. Raamat räägib Lagerfeldi noorusajast ja tema konkurentsist moekunstnik Yves Saint Laurent'iga 1970. aastate Pariisis

  17. Karl Lagerfeld obidelsja

    Index Scriptorium Estoniae

    2006-01-01

    Moekunstnik Karl Lagerfeld kaebas kohtusse raamatu "The Beautiful Fall : Fashion, Genius and Glorious Excess in 1970s Paris" autori Alicia Drake'i. Raamat räägib Lagerfeldi noorusajast ja tema konkurentsist moekunstnik Yves Saint Laurent'iga 1970. aastate Pariisis

  18. 11 juillet 2014 - Y. Bréchet Haut-Commissaire à l’énergie atomique et aux énergies alternatives (CEA) en France

    CERN Multimedia

    Barnard, Henry

    2014-01-01

    Monsieur Yves Bréchet en visite dans le tunnel du LHC au Point 5 ainsi que la caverne expérimentale de CMS avec T. Camporesi, Porte-parole de la Collaboration CMS. Signature du livre d'or avec F. Bordry, Directeur des accélérateurs et de la technologie.

  19. Unustatud katakombid / Claudia Haj Ali

    Index Scriptorium Estoniae

    Haj Ali, Claudia

    1999-01-01

    Arheoloog Jean-Yves Empereur leidis Egiptuse Aleksandria linna lähedal asuvasse kaljusse rajatud katakombid, mis on osa hellenistlikul perioodil rajatud ning pikka aega unustuse hõlmas olnud surnute linnast. Leidude seas on kipsist Meduusa pea nind leide Rooma perioodist.

  20. Development and Evaluation of a Korean Treebank and its Application to NLP

    Science.gov (United States)

    2002-01-01

    derivations automatically extracted from the Treebank with Xia’s (Xia et al., 2000a) LexTract. In a probabilistic TAG ( Schabes , 1992; Resnik, 1992), each word...thesis, University of Pennsylvania. Yves Schabes . 1992. Stochastic lexicalized tree-adjoining grammars. In Proceedings of COLING ’92, volume 2, pages 426

  1. Artificial Intelligence (AI) Center of Excellence at the University of Pennsylvania

    Science.gov (United States)

    1989-10-01

    Earley-Type Parsing Algorithm For Tree Adjoining Grammars Yves Schabes and Aravind K. Joshi MS-CIS-88-36 LINC LAB 113 We will describe and Earley...TAG’s ( Schabes and Joshi 1988) and "simple constraints" through the use of "dummy from Some recent linguistic work in TAGs (Abeille irnervals" and "fukzy

  2. Educating engineering designers for a multidisciplinary future

    DEFF Research Database (Denmark)

    Contemporary companies on a global market are experiencing constantly changing business demands and increased competition. Increasing focus in product development is now put on issues like understanding users and their needs, the context where users’ activities take place and creating sustainable....... actor-network that support and supply these activities throughout the product’s life. Based on the analysis, goals are set for the improved solution and concepts are developed for a new product/service-system. This way the students are lead through engineering and socio-technical analysis tasks...... as essential competencies in product/service-system design and functional product development. References Larsson, A., Larsson, T., Leifer, L., Van der Loos, M., Feland, J. (2005), Design for Wellbeing: Innovations for People, In proceedings of 15th International Conference on Engineering Design, ICED 05...

  3. Negotiating the Political Self on Social Media Platforms An In-Depth Study of Image-Management in an Election-Campaign in a Multi-Party Democracy

    OpenAIRE

    Jakob Svensson

    2012-01-01

    The elections 2010 were the first in Sweden where social media platforms were used to a large extent by politicians and parties in their campaigns. In this paper we follow the liberal parliamentarian Nina Larsson, who in tandem with traditional election campaigning used social media platforms with the guidance of a local communication agency, Hello Clarice. The paper is theoretically grounded in an understanding of our time as late modern, of social media use as expressive and web campaigning...

  4. International Physics Olympiad (24th) Held in Williamsburg, Virginia on July 10 - 18, 1993

    Science.gov (United States)

    1993-07-18

    27.35 Bojan Gornik Slovenia 27.33 Yoo Chul Chung Korea 27.25 Andras Major Germany 27.05 Robert Kry Canada 27 Erik Larsson Sweden 27 lacopoCarusotto...Martin Canada: Kry, Robert China: Zhang, Junan Colombia: Massey, Ibrahim Croatia:. Garaj, Slaven Cuba: Campa, Erwin Portuondo Cyprus: Tofaris...2159 REPUBLIC OF KOREA Singapore Sooyong Kim Dept. of Physics Meng Hau Kuok Korea Advanced Inst. of Science & National University Technology of

  5. 30. X tähistab EKA 90. aastapäeva

    Index Scriptorium Estoniae

    2004-01-01

    Näitustest. 29. X audoktorite Udo Kultermanni ja Juhani Pallasmaa loengud ning ümarlaud "Disain, tulevik ja identiteet", kus esitavad ettekande Halldor Gislason (Reykjavik), Francois Penz (Cambridge), Bruce Brown (Brighton), Peter McGrory (Helsingi) ja Michael U. Hensel (London), ümarlauda juhib Jüri Soolep. 30. X vilistlaspäev, audoktoriteks promoveeritakse Juhani Pallasmaa, Udo Kultermann, Lars Olof Larsson ja Yrjö Sotamaa

  6. Relationship between Gastrointestinal Peptides, Intestinal Wall Compliance, and Vascular Resistance

    Science.gov (United States)

    1983-01-20

    elevations in pan - creatic secretions which were both enzyme and bicarbonate rich. These responses could be reproduced by Intravenous Infusions of low doses...Increases in blood flow to the duodenum, jejunum, and pan - creas (all three vascular beds are perfused by this artery). Yet, al- though the superior...Immunohisto- chemical localization of a vasodilatory polypeptide (VIP) in cerebro - vascular nerves. Brain Res. 113: 400-404, 1976, 135. Larsson, L,-I., J

  7. Du roman policier au territoire touristique. Ystad, Stockholm: enquête sur les phénomènes Wallander et Millénium

    OpenAIRE

    Sylvain Guyot; Jacques Migozzi

    2016-01-01

    Stockholm and Ystad seem to have paradoxically taken advantage of Stieg Larsson's Millennium Trilogy and Henning Mankell's Wallander to attract tourists. How can crime fiction, which by nature is critical, become a tool for tourist marketing? The tourist construction is based pays close attention to the fictional writing of space; each of the two corpus displaying a highly distinct version. We thus need to question the weight of actors' strategies in the evolution of identity of places of crime.

  8. An unusual central retinal dystrophy associated with ichthyosis vulgaris.

    Science.gov (United States)

    Saatci, O A; Ozbek, Z; Köse, S; Durak, I; Kavukçu, S

    2000-06-01

    A number of ichthyosis syndromes may have retinal abnormalities such as the retinitis pigmentosa-like diffuse rod-cone dystrophy in Refsum's syndrome and the maculopathy in Sjögren-Larsson syndrome. We present two sisters who have an unusual, almost identical, bilaterally symmetric central retinal dystrophy associated with ichthyosis vulgaris in the absence of other systemic disorders. We believe that this dystrophy has not been previously described in patients with any of the known varieties of ichthyosis.

  9. Press Clippings of Swedish Scientific and Military Personalities.

    Science.gov (United States)

    2007-11-02

    ailments, glaucoma , allergies, etc., that Dr. Ljorklund, who holds no permanent office in Sweden, occupies himself. in his few square meters of laboratory...visits to Japanese institutions and to institutions in Calcutta and Bombay. Professor G. Klein, Stockholm, 98,500 kr for continued cyto- genetic ...population- genetic and immunologic work with experimental tumorst Professor L. G. Larsson, Umea, 75,000 kr for supplementary equipment for the isotope

  10. Data-Driven Lead-Acid Battery Prognostics Using Random Survival Forests

    Science.gov (United States)

    2014-10-02

    Data-Driven Lead-Acid Battery Prognostics Using Random Survival Forests Erik Frisk1, Mattias Krysander2, and Emil Larsson3 1,2,3 Department of...driven approach using random survival forests is proposed where the prognostic algorithm has access to fleet manage- ment data including 291 variables...but it is also used to, for example, power auxiliary units such as heating and kitchen Erik Frisk et al. This is an open-access article distributed

  11. 30. X tähistab EKA 90. aastapäeva

    Index Scriptorium Estoniae

    2004-01-01

    Näitustest. 29. X audoktorite Udo Kultermanni ja Juhani Pallasmaa loengud ning ümarlaud "Disain, tulevik ja identiteet", kus esitavad ettekande Halldor Gislason (Reykjavik), Francois Penz (Cambridge), Bruce Brown (Brighton), Peter McGrory (Helsingi) ja Michael U. Hensel (London), ümarlauda juhib Jüri Soolep. 30. X vilistlaspäev, audoktoriteks promoveeritakse Juhani Pallasmaa, Udo Kultermann, Lars Olof Larsson ja Yrjö Sotamaa

  12. Komitee mehed / Mihkel Kärmas

    Index Scriptorium Estoniae

    Kärmas, Mihkel, 1974-

    1999-01-01

    Kaheksa aastat pärast ENSV KGB likvideerimist on endised julgeolekutöötajad läbi löönud äris: R. Sillar, J. Zimin, V. Pool, A. Kruuser, E. Bluman, V. Konovalov, M. Trofimov, P. Härma, M. Larsson, P. Toom jt. Ilmunud ka: Narvskaja Gazeta 9. dets. lk. 5, Vesti : Nedelja Pljus 19. nov., lk. 11

  13. Você conhece esta síndrome? Do you know this syndrome?

    Directory of Open Access Journals (Sweden)

    Marcela Duarte Villela Benez

    2010-12-01

    Full Text Available Relatamos um caso típico, em um paciente masculino de 20 anos, da síndrome de Sjögren-Larsson, que é uma doença neurocutânea, autossômica recessiva e incapacitante, caracterizada por ictiose congênita, plegia espástica e retardo mental. É causada pela deficiência da enzima aldeído graxo desidrogenase. Não tem cura, porém a maioria dos pacientes sobrevive até a idade adulta. O tratamento deve ser multidisciplinar e a terapia dermatológica tem o objetivo de aliviar o prurido persistente e a ictiose.We report a typical case of Sjogren-Larsson syndrome in a male patient, aged 20. The Sjogren-Larsson syndrome is a neurocutaneous, autosomal recessive and disabling condition, characterized by congenital ichthyosis, spastic paraplegia and mental retardation. It is caused by deficiency of the microsomal enzyme fatty aldehyde dehydrogenase. It has no cure, but most patients survive up to an adult age. Treatment should be multidisciplinary and dermatological therapy aims at relieving the persistent itching and ichthyosis.

  14. Psicologia do estilo: nas bordas da atividade

    Directory of Open Access Journals (Sweden)

    Maria Elizabeth Barros de Barros

    2010-01-01

    Full Text Available This article is a discussion about the modes of intervention in the worlds of work from the proposals made by the Clinic of Activity, which has the psychologist Yves Clot as its main interlocutor, who is building a psychology of style, in intercession with the thought of Gilles Deleuze configuring itself as a Philosophy of Difference. It considers labor activity as a transitional result of a conflict that never ends in an action and of the task which is always reset at work in situation. It tries the implications of a clinic allied to the processes of styling involved in the industrious activity. It presents some connections between the ideas of Gilles Deleuze and the concepts of gender and style from Yves Clot. In this transit between clinics proposals, this article assures the activity in its relationship with the invention of modes of living and expanding life.

  15. Psicologia do estilo: nas bordas da atividade

    Directory of Open Access Journals (Sweden)

    Maria Elizabeth Barros de Barros

    2010-04-01

    Full Text Available This article is a discussion about the modes of intervention in the worlds of work from the proposals made by the Clinic of Activity, which has the psychologist Yves Clot as its main interlocutor, who is building a psychology of style, in intercession with the thought of Gilles Deleuze configuring itself as a Philosophy of Difference. It considers labor activity as a transitional result of a conflict that never ends in an action and of the task which is always reset at work in situation. It tries the implications of a clinic allied to the processes of styling involved in the industrious activity. It presents some connections between the ideas of Gilles Deleuze and the concepts of gender and style from Yves Clot. In this transit between clinics proposals, this article assures the activity in its relationship with the invention of modes of living and expanding life.

  16. Portrait. Nicolas Bourriaud

    OpenAIRE

    Muracciole, Marie

    2012-01-01

    L’art est entré dans la vie de Nicolas Bourriaud par la bibliothèque familiale, à Niort, avant d’en faire l’expérience en 1983 dans l’exposition Yves Klein au Centre Pompidou. Le catalogue lui apparaît comme une mine d’or. Il a dix-sept ans, et Pierre Restany, prescripteur littéraire du Nouveau Réalisme, restera pour lui un modèle. En 1985, Bourriaud fonde avec Jean-Yves Jouannais et Christophe Duchatelet la société Perpendiculaire, et en 1995 la revue éponyme. Un pamphlet de Bourriaud dans L...

  17. The LHC at the AAAS

    CERN Multimedia

    CERN Bulletin

    2011-01-01

    The American Association for the Advancement of Science held its annual meeting in the Walter E. Washington Convention Center in Washington D.C. last week.   Veteran science writer Tim Radford introduces LHC scientists during a media briefing at the AAAS annual meeting. Left to right: Felicitas Pauss, Tom LeCompte, Yves Schutz and Nick Hadley. As the world’s largest popular science meeting, the AAAS meeting is a major event in the calendar of science journalists.  At this year’s LHC session, CERN’s coordinator for international relations, Felicitas Pauss, opened the discussion, paving the way for Tom LeCompte of ATLAS, Joe Incandela of CMS, Yves Schutz of ALICE and Monica Pepe-Altarelli of LHCb to report on the status of the first year’s analysis from their experiments.    

  18. Europan 9 soosis Tartut / Urmas Oja

    Index Scriptorium Estoniae

    Oja, Urmas, 1981-2012

    2008-01-01

    Üleeuroopalise arhitektuurikonkursi "Europan 9" tulemused Eesti võistlusaladel. Tallinna Paljassaare sadamaala: II koht - töö "Veeäärse linna arendamine", Sayman Bostanci, ära märgiti töö "Urbland" (loetletud 11 itaalia arhitekti). Tartu Annelinna-äärne loodusväärtuslik krunt: I koht - "Linlik ökosüsteemi disain", Pierre-Yves Rustant, II - "Illusiooni taskud", Yuri Gerrits, Martin Birgel

  19. Tissue inhibitor of matrix metalloproteinases-1 loaded poly(lactic-co-glycolic acid) nanoparticles for delivery across the blood–brain barrier

    OpenAIRE

    Chaturvedi M.; Molino Y; Sreedhar B; Khrestchatisky M; Kaczmarek L

    2014-01-01

    Mayank Chaturvedi,1 Yves Molino,2 Bojja Sreedhar,3 Michel Khrestchatisky,4 Leszek Kaczmarek1 1Laboratory of Neurobiology, Nencki Institute, Warsaw, Poland; 2Vect-Horus, Marseille, France; 3Indian Institute of Chemical Technology, Hyderabad, India; 4Aix-Marseille Université, CNRS, NICN, UMR7259, Marseille, France Aim: The aim of this study was to develop poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) for delivery of a protein – tissue inhibitor of matrix metallo...

  20. Velocity Management and the Revolution in Military Logistics

    Science.gov (United States)

    1999-02-01

    affairs unless there is a revolution in military logistics ." When General Reimer identified the Revolution in Military Logistics (RML) as a necessary...Forces" (Parameters, Winter 1997-98), Lieutenant Colonel Yves J. Fontaine counters the Chief with another precondition: "The revolution [in military ... logistics ] will occur only after our research community provides us with combat equipment that minimizes the logistical tail needed to sustain it

  1. NATO, the Subjective Alliance: The Debate Over the Future

    Science.gov (United States)

    1988-04-01

    in Yves Montand, the popular French actor and chanson - nier.𔃾 If it was fair for Krauss to cite Montand as a spokesman for France, it was also fair...The French act more self-sufficiently than the others, enjoy- ing general voter support for maintenance of their com- pletely independent nuclear...logi- cal ends, the French , more than other European NATO members, fear the effect of the zero-zero agreement on U.S. decoupling. They have also feared

  2. Tactical UAV’s in the French Army

    Science.gov (United States)

    2007-11-02

    DLRFCMP SDTI Maintien en service jusqu’à l’arrivée du MCMMContrat Fabrication CL 289 Contrat Retrofit drone Adaptation véhicules Maintien en...Tactical UAV’s in the French Army LtCol Pierre-Yves HENRY, Technical Service of the French Army, Program Officer for Battlefield Surveillance Report...suggestions for reducing this burden, to Washington Headquarters Services , Directorate for Information Operations and Reports, 1215 Jefferson Davis

  3. Digital resource

    Directory of Open Access Journals (Sweden)

    Redazione Reti Medievali (a cura di

    2012-01-01

    Full Text Available Decretum Gratiani, Edizione di Emil Friedberg, Leipzig 1879-81 Iura communia. Il sito di diritto comune, a cura di Mario Montorzi Università di Pisa (1997-2003 La memoria degli Sforza, Edizione dei registri delle missive di Francesco I Sforza The Roman Law Library, Ed. by Alexandr Koptev, Yves Lassard Université Pierre Mendès - Grenoble 2 Statuti della Liguria Statuti medievali Senato della Repubblica – Biblioteca Web Gallery of Art

  4. The team responsible for repairing the cryoline's service modules in Building 110.

    CERN Multimedia

    Patrice Loïez

    2005-01-01

    Front row, from left to right: Jean-Marc Rinaldi, Said Atieh, who supervises the team, Jean-Paul Bacher, the Section Leader, and Isabel Bejar Alonso. Back row, from left to right: Jean-Luc Guerraz, Sylvain Nichilo, Jean-Michel Laurent, Guy Bogey, Jean-Michel Malin, Yves Depollier, Arezki Amarat and Fabien Antoniotti. Three other members of the team, Michel Caccioppoli, Mokhtar Hadjras and Julien Pellerin, are not in the picture

  5. The teaching of vectors in mathematics and physics in France during the 20th century

    OpenAIRE

    Ba, Cissé; Dorier, Jean-Luc

    2010-01-01

    The work presented in this text is part of a doctorial dissertation in mathematics education (Ba 2006) about the teaching and learning of vectors, translations, forces, velocity and movement of translation in mathematics and physics. Here, we present the evolution of the teaching of vectors and vector quantities in mathematics and physics from the end of the 19th century up to now. We analyse this evolution in the light of the ecology of knowledge, as developed by Yves Chevallard (1994). This...

  6. Historical trajectories of fashion: from ancient luxury to its democratization

    Directory of Open Access Journals (Sweden)

    António Machuco Rosa

    2014-08-01

    concept of luxury as opposed to the social significance that luxury possessed in premodern societies. The evolution of luxury is seen within the context of the evolution of fashion, highlighting how it participates in the emergence of modern forms of display of individual desire. This evolution is analyzed through four historical examples: the dandy “Beau” Brummell, the haute couture initiated by Frederik Worth, the creations of Yves Saint Laurent and the collections that Karl Lagerfeld developed for H&M.

  7. Domain decomposition methods for mortar finite elements

    Energy Technology Data Exchange (ETDEWEB)

    Widlund, O.

    1996-12-31

    In the last few years, domain decomposition methods, previously developed and tested for standard finite element methods and elliptic problems, have been extended and modified to work for mortar and other nonconforming finite element methods. A survey will be given of work carried out jointly with Yves Achdou, Mario Casarin, Maksymilian Dryja and Yvon Maday. Results on the p- and h-p-version finite elements will also be discussed.

  8. Different Points of View Concerning the Didactic Transposition

    OpenAIRE

    2011-01-01

    The present article treats the concept of Didactic Transposition, taking as reference the work of Yves Chevallard, La transposición didáctica: del saber sabio al saber enseñado (2005). We compared the adduction of the concept in several works, such as thesis, dissertations and articles, and discussed the multiple impressions concerning the process of didactic transposition. These papers show that the conceptualizations are not well defined, entailing dubiousness and discussions. Some differen...

  9. Tbilissi envoûté par le charme

    CERN Multimedia

    Cet article a été rédigé d'après des notes que nous a obligeamment fournies Yves Goldschmidt-Clermont; d'autres participants à la Conférence de Tbilissi, trop nombreux pour être cités, nous ont également apporté des compléments d'informations. Qu'ils en soient ici remerciés.

  10. Partial Differential Equations and Continuum Models of Phase Transitions (Equations aux Derivees Partielles et Modeles Continus de Transitions de Phases)

    Science.gov (United States)

    1988-01-22

    all simultaneously. ANALOGIES ENTRE DIGITATIONS VISQUEUSES ET CROISSANCE DENDRI TIQUE Yves COUDER(*) When, between two narrowly spaced glass plates, a...consider viscoelastic fluids which obey an Oldroyd type constitutive equation with retardation time. For the mixed Cauchy problem with homogeneous...visco61astiques d6crits par une 1oi de comportement do type Oldroyd avec temps de retard . On montre, pour le probl~me de Cauchy mixte avec conditions

  11. A few words of thanks

    CERN Multimedia

    Wells, P S

    I would like to thank all the people who have contributed articles and ideas to this first issue of the ATLAS eNews. In particular I would like to thank the following members of ETT/DH group (support for the CERN Document Server) who have set up the various web interfaces, turned our vague ideas for the style into reality, and dealt with numerous questions: Thomas Baron, Roberta Faggian, Julie Gonzalez, Jean-Yves Le Meur and Tibor Simko.

  12. Composition of the college

    OpenAIRE

    2017-01-01

    Under the direction of Pierre-Yves Le Meur, anthropologist, IRD Experts and coordination of the axis Pierre Cochonat, geologist-marine geoscience, formerly of Ifremer Carine David, lawyer, New Caledonia University Vincent Geronimi, economist, Versailles St-Quentin University Sarah Samadi, biologist, National Museum of Natural History Experts Nicholas Arndt, geochemist, Grenoble Alpes University Tamatoa Bambridge, anthropologist, CNRS Patrice Christmann, geologist-mineral resources strategy, B...

  13. 法国现代艺术家伊夫克莱因作品回顾展

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Yves Klein(伊夫克莱因)被视为波普艺术最重要的代表人物之一,与沃霍尔(Andy Warhol)、杜尚(Marcel Duchamp)和博伊于斯(Joseph Beuys)一起,并称为20世纪后半叶对世界艺术贡献最大的四位艺术家。

  14. Building a Large Annotated Corpus of English: The Penn Treebank

    Science.gov (United States)

    1993-04-30

    Brill 1991]) or the skeletally parsed corpus ([Weischedel et al 1991], [Pereira and Schabes 1992]). The POS-tagged corpus has also been used to train a...Niv 1991] Niv, Michael, 1991. Syntactic disambiguation. In The Penn Review of Linguistics 14, pages 120-126. [Pereira and Schabes 1992] Pereira...Fernando and Schabes , Yves. 1992. Inside-outside reestimation from partially bracketed corpora. In Proceedings of the 30th Annual Meeting of the

  15. Stress and Psychological Support in Modern Military Operations (Stress et aide psychologique dans les operations militaires modernes)

    Science.gov (United States)

    2008-04-01

    Tools in Use Country where used France Name of Tool D5D system Author(s) (Name/e-mail) Jean -Pierre ROLLAND and Jean - Luc MOGENET/2001...FLECK, Guenther AUT 2002 Member LANGER, Christian AUT 2003 Member CUVELIER, Yves BEL 2002 – 2006 Chair DE SOIR, Erik BEL 2002 Member FILS, Jean ...Member MATHESON, Henry CAN 2003 – 2005 Member NORRIS, Marie CAN 2005 – 2006 Member PERRON, Nancy CAN 2004 – 2005 Member RODRIGUE, Suzie CAN 2006 Member

  16. Inherited ichthyosis: Syndromic forms.

    Science.gov (United States)

    Yoneda, Kozo

    2016-03-01

    Among diseases that cause ichthyosis as one of the symptoms, there are some diseases that induce abnormalities in organs other than the skin. Of these, diseases with characteristic signs are regarded as syndromes. Although these syndromes are very rare, Netherton syndrome, Sjögren-Larsson syndrome, Conradi-Hünermann-Happle syndrome, Dorfman-Chanarin syndrome, ichthyosis follicularis, atrichia and photophobia (IFAP) syndrome, and Refsum syndrome have been described in texts as representative ones. It is important to know the molecular genetics and pathomechanisms in order to establish an effective therapy and beneficial genetic counseling including a prenatal diagnosis.

  17. 谁捅了马蜂窝——《千禧年》系列推理悬疑小说

    Institute of Scientific and Technical Information of China (English)

    许秀云

    2011-01-01

    @@ 尽管推理悬疑小说己经屡见不鲜,但能像这样产生轰动效应的系列却并不多见.作者为瑞典作家斯蒂格·拉森(Stieg Larsson,1954-2004).他于2001年开始创作该系列,到2004年共完成了(The Girl with the Dragon Tattoo)、(The Girl Who Played with Fire)和(The Girl Who Kicked the Hornets'Nest)等三部作品.

  18. Ultraviolet B Irradiance and Vitamin D Status are Inversely Associated With Incidence Rates of Pancreatic Cancer Worldwide

    Science.gov (United States)

    2010-01-01

    Serum levels of vitamin D metabolites and the subsequent risk of colon and rectal cancer in Finnish men. Cancer Causes Control. 1997;8:615Y625. 17...of breast,10Y14 colon ,14Y19 and ovary.20 While dietary and lifestyle factors are well established and highly relevant to risk of pancreatic cancer ...pancreatic cancer . J Cell Biochem. 2005;95:649Y656. 4. Michaud DS. Epidemiology of pancreatic cancer . Minerva Chir. 2004;59:99Y111. 5. Larsson SC, Permert J

  19. Bicontinuous liquid crystals

    CERN Document Server

    Lynch, Mathew L

    2005-01-01

    PrefaceIntroduction AcknowledgmentsBicontinuous Cubic Liquid Crystalline Materials: A Historical Perspective and Modern Assessment; Kr̄e LarssonIntermediate Phases; Michael C. Holmes and Marc S. LeaverCubic Phases and Human Skin: Theory and Practice; Steven Hoath and Lars NorlňThe Relationship between Bicontinuous Inverted Cubic Phases and Membrane Fusion; D.P. SiegelAspects of the Differential Geometry and Topology of Bicontinuous Liquid-Crystalline Phases; Robert W. CorkeryNovel L3 Phases and Their Macroscopic Properties; R. Beck and H. HoffmannBicontinuous Cubic Phases of Lipids with Entra

  20. EKA 90. aastapäeva juubelinädalale on planeeritud mitmeid üritusi nii peamajas kui osakondades

    Index Scriptorium Estoniae

    2004-01-01

    Kunstööstuskooli tutvustavast näitusest. 29. X audoktorite Udo Kultermanni ja Juhani Pallasmaa loengud ning ümarlaua ettekanded (osalejad loetletud), ümarlauda juhib Jüri Soolep. EKA galeriis valgusinstallatsioonide näitus "Think Lightly", osalevad Sirli Põllumäe, Riho Tiivel, Helis Podnek, Marion Uuspõld, Pent Talvet, Mehis Tiitsar, Merike Rehepapp, Veiko Vaine. Üliõpilaste loomingu väljapanekud. 30. X vilistlaspäev, pidulikul aktusel promoveeritakse audoktoriteks Juhani Pallasmaa, Udo Kultermann, Lars Olof Larsson ja Yrjö Sotamaa. Vabade kunstide osakonna rändnäitus "Ekskursioon" sisekaitseakadeemias

  1. Attention-deficit hyperactivity disorder and the shifting sands of psychiatric nosology.

    Science.gov (United States)

    Faraone, Stephen V

    2013-08-01

    Larsson et al provide epidemiological evidence for a genetic association between attention-deficit hyperactivity disorder (ADHD) and both bipolar disorder and schizophrenia and Hamshere and colleagues confirm the latter association with genome-wide data. Although a genetic link between ADHD and bipolar disorder has been hypothesised for over a decade, the association with schizophrenia fills a notable gap in the literature. This editorial discusses the implications of these findings for clinicians, who must address psychiatric comorbidity in their treatment formulations, and researchers who are learning that the discrete categorical diagnoses of our diagnostic systems may not be up to the task of clarifying the causes and cures of psychopathology.

  2. Mænd der hader kvinder - et værk der bryder grænser

    OpenAIRE

    Nelausen, Raymund; Borberg, Ida; Storm, Sigrid; Børnick, Nicolai; Poulsen, Annemette

    2015-01-01

    The assignment investigates how the novel Mænd der hader kvinder (2005) by Stieg Larsson breaks down the boundaries between men and women, reality and fiction, hero and antihero, and between victim and executioner. It also looks into how the two film adaptations, Mænd der hader kvinder (2008) and The Girl with The Dragon Tattoo (2011), relate to the novel and how they treat the themes within the book. In our analysis of the novel and the two adaptations, we have applied the relevant theories ...

  3. Supra-molecular structure and chemical reactivity of cellulose I studied using CP/MAS (sup)13 C-NMR

    CSIR Research Space (South Africa)

    Chunilall, Viren

    2013-08-01

    Full Text Available medium, provided the original work is properly cited. Supra-Molecular Structure and Chemical Reactivity of Cellulose I Studied Using CP/MAS 13C-NMR Viren Chunilall, Tamara Bush and Per Tomas Larsson Additional information is available at the end... of Cellulose I Studied Using CP/MAS 13C-NMR 71 1.1.2. Dissolving pulp The unbleached pulp that results after acid bi-sulphite pulping is used as raw material for dissolving pulp production. Lignin and hemicelluloses in the unbleached pulp are considered...

  4. Integrated Resources and Training Facilitation

    DEFF Research Database (Denmark)

    Khalid, Md. Saifuddin; Islam, Kamrul; Nyvang, Tom

    2013-01-01

    (Larsson & Holmström, 2007), interview data on the decision-making experience of computer purchases, and the after-purchase experience of learning computer-related skills, the integration of the technology and the skills in interviewees’ (students and teachers) learning environments is analyzed......In a rural context in a developing country purchasing a computer and connecting it to the Internet is in itself difficult, even when the lack of money is a minor issue. These issues prevent individuals in rural communities from familiarizing themselves with educational technology and ICT in general...

  5. A Random Walk to Economic Freedom?

    Directory of Open Access Journals (Sweden)

    Witte, Mark David

    2013-04-01

    Full Text Available Given the wide use of economic freedom in economic literature it is imperative to understand how economic freedom evolves. Results suggest that levels of economic freedom are dominated by random shocks. Using a test for stationarity devised by Westerlund and Larsson (2012 we are unable to reject the null hypothesis of a random walk. The changes to economic freedom also are mostly driven by random shocks with only a minor role played by country specific characteristics. Additionally, changes to economic freedom are partially reversed as increases (decreases in one year are partially offset by decreases (increases in the next year.

  6. Game engine gems 2

    CERN Document Server

    Lengyel, Eric

    2011-01-01

    GRAPHICS AND RENDERINGFast Computation of Tight-Fitting Oriented Bounding Boxes; Thomas Larsson (Senior Lecturer at Mälardalen University) & Linus Källberg (Lecturer at Mälardalen University)Modeling, Lighting, and Rendering Techniques for Volumetric Clouds; Frank Kane (Founder of Sundog Software, LLC)Simulation of Night-Vision and Infrared Sensors; Frank Kane (Founder of Sundog Software, LLC)Screen-Space Classification for Efficient Deferred Shading; Balor Knight (Senior Principal Programmer at Black Rock Studio), Matthew Ritchie (Principal Programmer at Black Rock Studio), George Parrish (Se

  7. EMQN Best Practice Guidelines for molecular genetic testing of SCAs

    OpenAIRE

    Sequeiros, Jorge; Martindale, Joanne; Seneca, Sara

    2010-01-01

    Other participants at the EMQN Best Practice Meeting and/or at the electronic discussions thereafter were Isabel Alonso, Anna Andersson, David Barton, Nazli Bazac, Kyproula Christodoulou, Luís Correia, Mark Davis, Mary Davis, Rob Elles, Marina Frontali, Javier Garcia-Planells, Paola Giunti, Petra Hämäläinen, Jenni Jonasson, Outi Kamarainen, Nina Larsson, Eric Leguern, Monique Losekoot, Carla Martins, Michael Morris, Clemens Müller-Reible, Simon Patton, M Luiza Saraiva-Pereira, Jorge Pinto-Bas...

  8. Marknadskommunikation i förändring : En studie i hur PR-byråers marknadskommunikation har förändrats under första decenniet på 2000-talet med bakgrund i sociala medier

    OpenAIRE

    Holm, Gabriella; Larsson, Chrisfoffer

    2012-01-01

    Title: Market Communication in transformation Authors: Gabriella Holm and Christoffer Larsson Purpose/Aim: The purpose of this paper is to examine how market communication at PR-firms in Sweden has changed over the first decade of the 21-century. In 2007 social media expanded on the Swedish market. This had implications for the way we are looking at communication and therefore also the PR business and how they are operating. The aim with this paper is to see how social media have affected mar...

  9. Negotiating the Political Self on Social Media Platforms An In-Depth Study of Image-Management in an Election-Campaign in a Multi-Party Democracy

    Directory of Open Access Journals (Sweden)

    Jakob Svensson

    2012-12-01

    Full Text Available The elections 2010 were the first in Sweden where social media platforms were used to a large extent by politicians and parties in their campaigns. In this paper we follow the liberal parliamentarian Nina Larsson, who in tandem with traditional election campaigning used social media platforms with the guidance of a local communication agency, Hello Clarice. The paper is theoretically grounded in an understanding of our time as late modern, of social media use as expressive and web campaigning as to large extent revolving around image-management. The research question that will be attended to in this paper is how Nina Larsson used social media platforms in her campaign negotiate the image of herself. The methods used for empirical data-gathering are inspired by (nethnography, with both participant observation online and offline, interviews as well as content analyses of Nina's social media postings. Results indicate that she used social media platforms to control her political image, to amplify selected text - texts that often originated in offline/broadcast media – and to negotiate a position within the Liberal Party rather than to deliberate with potential voters.

  10. A relevância de Klein hoje

    Directory of Open Access Journals (Sweden)

    Yve-Alain Bois

    2010-01-01

    Full Text Available Para se aproximar do trabalho de Yves Klein, o autor reproduz alguns argumentos de Theodor Adorno sobre a música de Wagner, formulados em dois momentos - em 1937-1938, sob a experiência do fascismo, e em 1963, com 30 anos de "distância". No primeiro texto, Adorno mostrava, na obra de Wagner, os aspectos que traíam a gestação do fascismo. No segundo reconhecia que, com o novo momento histórico, outras camadas vinham à baila naquela obra; ela havia mudado, e a posição de Adorno em relação a ela tornava-se "ambivalente". Partindo do paralelismo com Wagner, Bois revisita o trabalho de Klein buscando revelar, em seus ardis e encenações, para além da simples adesão aos expedientes da indústria cultural, uma espetacularização do próprio espetáculo, que acaba por esvaziá-lo.In order to approach the work of Yves Klein, the author recalls the arguments of Theodor Adorno in regard to the music of Richard Wagner, presented in two different texts - the first written in 1937-1938, under the experience of fascism, and the other in 1963, with a "distance" of 30 years. In the first text, Adorno highlighted, in the work of Wagner, the aspects that betrayed the birth of fascism. In the second one he recognized that, along with the new historical moment, other layers emerged in Wagner's work; it had changed, and Adorno's position toward it became "ambivalent". Starting with a parallelism with Wagner, Bois reexamines the work of Yves Klein, trying to reveal, in his use of staging and artifice, beyond the mere acceptance of the expedients of the culture industry, a spectacularization of spectacle itself, that ends up by deflating it.

  11. Geoestratégias em confronto no Líbano em guerra (1975-90)

    OpenAIRE

    2011-01-01

    O presente estudo tem por objetivo caracterizar as Guerras do Líbano (1975-90) como resultantes do processo de desintegração do Império Otomano no quadro definido pela aceleração histórica de acordo com Yves Lacoste. Ela evidencia o processo/projeto balcanizador, ou seja, de divisão territorial em base étnica, do Líbano e do Oriente Médio iniciado com o expansionismo europeu a partir do séc. XIX e a continuidade dada a tal processo pelas modernas geoestratégias israelenses, as quais, com suas...

  12. Proceedings of Tunnel Detection Symposium on Subsurface Exploration Technology (4th) held in Golden, Colorado on 26 - 29 Apr 1993

    Science.gov (United States)

    1993-04-29

    REFERENCES 1. Waters, K. H., 1978, "Reflection Seismology. A Tool for Energy Resource Exploration," Wiley, 377 pp. 2. Obert , L., and W, I, Duvall, 1967...the centre frequency signal. TRACE NUMBER 0 10 20 (a) -70 -80- (dB) -90 -100 0 10 20 (b) -7r) -80 (dB) -90 -100 o-00 1o0 20 (C) -801 (dB) -90 -100...Richard J. Chignell Colorado School of Mines EMPAD Ltd. Golden, CO 80401 Surrey Tech Centre 40 Occam Road Yves Barbin Guildford GU2 544 Research

  13. Annex 4. The panel of experts

    OpenAIRE

    2013-01-01

    YVES BARBIN Veille technologique, prospection filière PAM (Plantes aromatiques et médicinales) Pierre Fabre Médicament – Plantes et Industries 16, rue Jean Rostand, BP92 – 81603 Gaillac VALÉRIE BOISVERT Économiste de l’environnement IRD – Centre d’Orléans 5, rue du Carbone – Technoparc – 45000 Orléans PIERRE CABALION Pharmacien, ethnopharmacologiste IRD – Centre de Nouvelle-Calédonie Laboratoire des Substances naturelles terrestres ...

  14. Annexe 4. Présentation du collège d’experts

    OpenAIRE

    2013-01-01

    YVES BARBIN Veille technologique, prospection filière PAM (Plantes aromatiques et médicinales) Pierre Fabre Médicament – Plantes et Industries 16, rue Jean Rostand, BP92 – 81603 Gaillac VALÉRIE BOISVERT Économiste de l’environnement IRD – Centre d’Orléans 5, rue du Carbone – Technoparc – 45000 Orléans PIERRE CABALION Pharmacien, ethnopharmacologiste IRD – Centre de Nouvelle-Calédonie Laboratoire des Substances naturelles terrestres ...

  15. José Obdulio Gaviria y su visión de Colombia

    OpenAIRE

    M., Alba Lucía Delgado

    2012-01-01

     “De allí la premisa central que invoca este gobierno: en Colombia no existe conflicto armado interno  sino una amenaza terrorista.” Luis Carlos Restrepo (Marzo 6, 2005). “A la luz del DIH, la situación existente en Colombia presenta todos los elementos constituyentes de un conflicto armado no internacional  (…) Se trata de un conflicto armado de carácter interno.” Yves Giovannoni (Mayo 3, 2005). En agosto de 2002 asume el poder como presidente de Colombia Álvaro Uribe Vélez para un períod...

  16. Euro-Paabel : arhitektuurivõistlus Europan 9 = Euro-Babel : Europan 9 Architecture Competition / Triin Ojari

    Index Scriptorium Estoniae

    Ojari, Triin, 1974-

    2008-01-01

    Žürii liige üleeuroopalisest arhitektuurikonkursist "Europan 9", tulemustest Eesti võistlusaladel. Tallinna Paljassaare sadamaala: II koht - töö "Developing a waterside city", Sayman Bostanci, ära märgiti töö "Urbland", Filippo Ortolani, Giulia Pedemonte, Ivan Esposito, Chiara Leone, Emiliano Auriemma, Francesco Bigi, Carola Clemente, Matteo Giannini, Barbara Del Brocco, Francesco Lai, Carlo Peiser. Tartu Annelinna ja Anne kanali vaheline ala: I koht - "Urban ecosystem design", Pierre-Yves Rustant, II - "Pockets of illusion", Yuri Gerrits, Martin Birgel, ergutuspreemia - Nuno Abrantes

  17. Opening Plenary : Communicating about Theoretical Geography

    Directory of Open Access Journals (Sweden)

    Denise Pumain

    2001-12-01

    Full Text Available First of all, I wish to thank Yves Guermond for drawing a superb image as a symbol of our colloquium. This superimposition of bookshelves on the Etretat cliffs reminds us of the splendid metaphor developed by Abraham Moles, the specialist in the psychology of space, about the wall of knowledge, which is continuously under construction, and to which each new piece of research adds a new brick. But might we not wonder whether there is not a risk that, as in the case of the Normandy cliffs last ...

  18. Opening Plenary : Communicating about Theoretical Geography

    OpenAIRE

    Denise Pumain

    2014-01-01

    First of all, I wish to thank Yves Guermond for drawing a superb image as a symbol of our colloquium. This superimposition of bookshelves on the Etretat cliffs reminds us of the splendid metaphor developed by Abraham Moles, the specialist in the psychology of space, about the wall of knowledge, which is continuously under construction, and to which each new piece of research adds a new brick. But might we not wonder whether there is not a risk that, as in the case of the Normandy cliffs last ...

  19. Euro-Paabel : arhitektuurivõistlus Europan 9 = Euro-Babel : Europan 9 Architecture Competition / Triin Ojari

    Index Scriptorium Estoniae

    Ojari, Triin, 1974-

    2008-01-01

    Žürii liige üleeuroopalisest arhitektuurikonkursist "Europan 9", tulemustest Eesti võistlusaladel. Tallinna Paljassaare sadamaala: II koht - töö "Developing a waterside city", Sayman Bostanci, ära märgiti töö "Urbland", Filippo Ortolani, Giulia Pedemonte, Ivan Esposito, Chiara Leone, Emiliano Auriemma, Francesco Bigi, Carola Clemente, Matteo Giannini, Barbara Del Brocco, Francesco Lai, Carlo Peiser. Tartu Annelinna ja Anne kanali vaheline ala: I koht - "Urban ecosystem design", Pierre-Yves Rustant, II - "Pockets of illusion", Yuri Gerrits, Martin Birgel, ergutuspreemia - Nuno Abrantes

  20. From Perceptual Apparatus to Immersive Field of Experience

    DEFF Research Database (Denmark)

    Wieczorek, Izabela

    2014-01-01

    , or orchestrators of emotions, many of these apparatuses were meant to be vehicles for regaining the consciousness of the body and the environment. Apparatuses that expand into space complete this particular genealogy – space itself becoming a mediating and conductive device capable of engendering these embedding...... situations, Sloterdijk remarks. Situated within the field of trans-disciplinary collaborations, the oeuvre of Werner Ruhnau comes to the fore as paradigmatic for illustrating these aspects. The joint projects with philosopher, artist and educator Hugo Kükelhaus, or artists such as Yves Klein and Adolf Luther...

  1. EC sponsorship for CDS Agenda and Webcast.

    CERN Multimedia

    Maximilien Brice

    2002-01-01

    The CERN Document Server Agenda and Webcast Services tool is now part of the European Commission s Integrated Digital Conferencing (InDiCo) project to develop a service platform for the production, archiving, searching and filtering of multimedia content from conferences and seminars. CERN is providing the agenda-management software, as well as a large collection of digital material that will be used for initial tests of the system. Pictured here are the members of the Document Handling group in Education and Technology Transfer division who are participating in the project: (left to right) Jean-Yves Le Meur, Erik Simon, Thomas Baron and Hector Sanchez.

  2. Gregory Bateson e o processo comunicativo

    OpenAIRE

    Lígia Campos de Cerqueira Lana

    2008-01-01

    Em busca de proposições para a definição do conceito de comunicação, este artigo apresenta a revisão de dois trabalhos de Gregory Bateson: Communication, the social matrix of psychiatry, de 1965, em co-autoria com Jurgen Ruesch e Communication, de 1971, capítulo de abertura da obra coletiva The natural history of an interview. Conforme Yves Winkin, o trabalho de Bateson situa-se no modelo orquestral da Comunicação, que postula a circularidade e a complexidade dos processos comunicativos. Greg...

  3. Interview of Robert H.Grubbs

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Robert H.Grubbs is a Nobel Laureate and the Victor and Elizabeth Atkins Professor of Chemistry at the California Institute of Technology,USA.He grew up in the State of Kentucky,and received his BS and MS degrees from the University of Florida.Grubbs conducted Ph.D.studies under the guidance ofRonald Breslow at Columbia University [1],and postdoctoral work with J AMes P.Collman at Stanford University.Grubbs shared the 2005 Nobel Prize in Chemistry with Yves Chauvin and Richard R.Schrock for "for the development of the metathesis method in organic synthesis" [2],among many honors and awards he has received.

  4. François Bayrou visits CERN

    CERN Multimedia

    2008-01-01

    On 3 July, François Bayrou, president of the French political party MOuvement DÉMocrate, visited CERN and took part in a round-table discussion. François Bayrou and Yves Schutz, from the ALICE collaboration, on the experimental site.As a politician, Mr Bayrou greatly appreciated the opportunity to hold discussions with CERN scientists on the international and collaborative nature of the science being done here, and on the development of particle physics over the next fifty years.

  5. Devjatõi arhitekturnõi konkurs Europan vporu Tartu / Urmas Oja

    Index Scriptorium Estoniae

    Oja, Urmas, 1981-2012

    2008-01-01

    Üleeuroopalise arhitektuurikonkursi "Europan 9" tulemused Eesti võistlusaladel. Tallinna Paljassaare sadamaala: II koht - töö "Developing a Waterside City", Sayman Bostanci. Tartu Annelinna-äärne loodusväärtuslik krunt: I koht - "Urban Ecosystem Design", Pierre-Yves Rustant, II - "Pockets of Illusion", Yuri Gerrits, Martin Birgel. Toodud ka kaks äramärgitud tööd, Rootsi-Eesti ühisžürii liikmed (Eestist Andres Alver, Triin Ojari, varuliige Inga Raukas)

  6. Edgar Morin, Pierre Nora, Michel Onfray, et al., Des Intellectuels jugent les médias

    Directory of Open Access Journals (Sweden)

    Nolwenn Mingant

    2012-03-01

    Full Text Available Des intellectuels jugent les médias is a collection of interviews published in French magazine Médias over the past five years. The ‘intellectuals’ in question are renowned philosophers (Daniel Bougnoux, André Compte-Sponville, Régis Debray, Yves Michaud, Michel Onfray, the Spanish Fernando Savater, historians (Marcel Gauchet, Pierre Nora, sociologists (Edgar Morin, and essayists (Philippe Sollers, Paul Virilio. In publishing these interviews, Mordicus Editions aims to help people to ‘bet...

  7. Are the rules for Didactical Transposition applicable to the concepts of modern physics?

    Directory of Open Access Journals (Sweden)

    Guilherme Brockington

    2005-12-01

    Full Text Available This study is part of a program to update the teaching curriculum. The subject matter of Modern and Contemporary Physics is generally absent in teaching at the Middle School level. In the study we analyse the requirements for the insertion of elements of Quantum Mechanics in teaching at that level. The analysis is based on the theory of “Didactical Transposition" proposed by Yves Chevallard and from which we point out some elements of his rules which are of questionable relevance to the topics of this "new" Physics.

  8. 烯烃复分解反应--2005年诺贝尔化学奖成果介绍%Olefin Metathesis--Introduction to Achievements of Nobel Prize for Chemistry 2005

    Institute of Scientific and Technical Information of China (English)

    高正曦; 姚祝军

    2005-01-01

    法国科学家伊夫·肖万(Yves Chauvin)和美国科学家罗伯特·格拉布(Robert H Grubbs)、理查德·施罗克(Richard R Schrock)3人因为发展了烯烃复分解反应在有机合成中的应用,而共享了2005年度的诺贝尔化学奖.简要介绍了烯烃复分解反应的原理、应用和发展简况,以及发现过程.

  9. Nobel Prize in Chemistry. Development of the Olefin Metathesis Method in Organic Synthesis

    Science.gov (United States)

    Casey, Charles P.

    2006-02-01

    The 2005 Nobel Prize in Chemistry was awarded to Yves Chauvin of the Institut Français du Pétrole, Robert H. Grubbs of CalTech, and Richard R. Schrock of MIT "for development of the metathesis method in organic synthesis". The discoveries of the laureates provided a chemical reaction now used daily in the chemical industry for the efficient and more environmentally friendly production of important pharmaceuticals, fuels, synthetic fibers, and many other products. This article tells the story of how olefin metathesis became a truly useful synthetic transformation and a triumph for mechanistic chemistry, and illustrates the importance of fundamental research. See JCE Featured Molecules .

  10. Roundtable:Research Opportunities and Challenges for Emerging Software Systems

    Institute of Scientific and Technical Information of China (English)

    张翔宇; 张冬梅; Yves Le Traon; 王青; 张路

    2015-01-01

    For this special section on software systems, several research leaders in software systems, as guest editors for this special section, discuss important issues that will shape this field’s future directions. The essays included in this roundtable article cover research opportunities and challenges for emerging software systems such as data processing programs (Xiangyu Zhang) and online services (Dongmei Zhang), with new directions of technologies such as unifications in software testing (Yves Le Traon), data-driven and evidence-based software engineering (Qing Wang), and dynamic analysis of multiple traces (Lu Zhang). — Tao Xie, Leading Editor of Special Section on Software System.

  11. Presencia y distribución de micofilas en gramíneas de Argentina

    Directory of Open Access Journals (Sweden)

    Lugo, Mónica A.

    1998-06-01

    Full Text Available The mycophyllas were studied in grasses (Poaceae from natural Argentinian grasslands. Festuca fiebrigii Pilg., F. hieronymi Hack. var. expansa (St. Yves Türpe, F. parodii St. Yves, Melica macra Nees, M. stuckertii Hack., Poa hieronymi Hack.. P. holciformis J. Presl, P. lilloi Hack., P. plicata Hack, and P. stuckertii (Hack. Parodi are reponed as new hosts and the distribution área of the association for Festuca arundinacea Schreb., F. hieronymi Hack, var. hieronymi and F. tucumanica E.B. Alexeev, has been extended. The interaction was a mutualistic symbiosis. Most of the species had both the culm parenchyma and the fruits colonized, except in Melica macra. Poa hieronymi and P. plicata, where the symbiont was only observed in the parenchyma. On the other hand, variation in the association was observed in relation to the host species, location and altitude.Se realiza un estudio de las micofilas encontradas en gramíneas (Poaceae de pastizales naturales de Argentina. La búsqueda del simbionte fúngico se efectuó en plantas vivas y herborizadas. Se dan a conocer como nuevos hospedantes a Festucafiebrigii Pilg., F. hieronymi Hack, var. expanda (St. Yves Türpe, F. parodii St. Yves, Melica macra Nees, M. stuckertii Hack., Poa hieronymi Hack., P. holciformis J. Presl, P. lilloi Hack., P. plicata Hack, y P. stuckertii (Hack. Parodi, y se amplía el área de distribución de la asociación para Festuca arundinacea Schreb., F. hieronymi Hack. var. hieronymi y F. tucumanica E.B. Alexeev. El tipo de interacción observada corresponde a una simbiosis mutualista. En la mayoría de las especies analizadas el endófito colonizó el parenquima de las cañas y los frutos, salvo en Melica macra. Poa hieronymi y P. alicata, en las que solo se observó en el parenquima. Por otro lado, la presencia de micofilas presentó variaciones con relación a la especie del hospedante, altitud y localidad de procedencia.

  12. TESTING OF TWO PROTOCOLS FOR GENOTYPING THE LEPTIN GENE LOCUS AND BODY MEASUREMENT IN MARAMURES BROWN AND ROMANIAN BREED CATTLE

    Directory of Open Access Journals (Sweden)

    CRINA TEODORA CARSAI

    2013-12-01

    Full Text Available The body measurement of Maramures Brown breed and Romanian Siemmental and testing two protocols for emphasizing the leptine gene in order to perform associations with some beef production traits within further studies were the aims of our research. The blood DNA extraction was performed according to the protocols proposed by Yves Amigues and genotyping protocols was proposed by Leifers and Pomp et al. The body weight is within standards. The analyzed protocols used for leptine gene emphasizing led to satisfactory results, which will enable us to perform further research in order to make associations between this possible marker gene and some body traits.

  13. TESTING OF TWO PROTOCOLS FOR GENOTYPING THE LEPTIN GENE LOCUS AND BODY MEASUREMENT IN MARAMURES BROWN AND ROMANIAN BREED CATTLE

    Directory of Open Access Journals (Sweden)

    CARSAI CRINA TEODORA

    2008-01-01

    Full Text Available The body measurement of Maramures Brown breed and Romanian Siemmental and testing twoprotocols for emphasizing the leptine gene in order to perform associations with some beef productiontraits within further studies were the aims of our research. The blood DNA extraction was performedaccording to the protocols proposed by Yves Amigues and genotyping protocols was proposed byLeifers and Pomp et al. The body weight is within standards. The analyzed protocols used for leptinegene emphasizing led to satisfactory results, which will enable us to perform further research in orderto make associations between this possible marker gene and some body traits.

  14. Analyse de régularité locale, quelques applications à l'analyse multifractale

    OpenAIRE

    2003-01-01

    Autres membres du jury: Jean-Michel Bony (Président), Ingrid Daubechies et Stéphane Jaffard (Rapporteurs), Albert Cohen et Yves Meyer (Examinateurs); In many scientific domains (signal and image processing, fully developed turbulence), it is important both from a theoretical and a practical viewpoint to be able to detect and to characterize thesingularities of an object. This object can either be a function, adistribution, a measure or a process.The first part of my work is focused on the cha...

  15. Devjatõi arhitekturnõi konkurs Europan vporu Tartu / Urmas Oja

    Index Scriptorium Estoniae

    Oja, Urmas, 1981-2012

    2008-01-01

    Üleeuroopalise arhitektuurikonkursi "Europan 9" tulemused Eesti võistlusaladel. Tallinna Paljassaare sadamaala: II koht - töö "Developing a Waterside City", Sayman Bostanci. Tartu Annelinna-äärne loodusväärtuslik krunt: I koht - "Urban Ecosystem Design", Pierre-Yves Rustant, II - "Pockets of Illusion", Yuri Gerrits, Martin Birgel. Toodud ka kaks äramärgitud tööd, Rootsi-Eesti ühisžürii liikmed (Eestist Andres Alver, Triin Ojari, varuliige Inga Raukas)

  16. “时间之廊”,溯源伯爵之梦

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>相信你所做的,做你所相信的。——伊芙·伯爵(Yves G.Piaget) 1874年,伯爵由年仅19岁的乔治·伯爵(Georges-Edouard Piaget)创立至今,仍以其为名承袭并开创历史。要了解伯爵自1874年至今的过百种珍品与历史文献记录,您只要前往伯爵的

  17. Nous remercions

    OpenAIRE

    2014-01-01

    Ruth Amossy Violaine Appel Aurélie Aubert Gloria Awad Julien Bertrand Aimé-Jules Bizimana Stephan Bratosin Philippe Braud Stéphane Cabrolié Dominique Cotte Alexandre Coutant Sébastien Couvrette Pierre De Senarciens Françoise Denoyelle Jean-Claude Deroubaix Guillaume Devin Jean-Pierre Esquenazi Patrick Eveno Sylvia Faure Jairo Ferreira François Foret Fanny Georges Laurent Gille Corinne Gobin Valérie Gorin Benoît Grevisse Jean Noël Kapferer Roselyne Koren Yves Krief Lylette Lacôte-Gabrysiak Pau...

  18. A model for Faraday pilot-waves over variable topography

    Science.gov (United States)

    Faria, Luiz

    2016-11-01

    In 2005 Yves Couder and co-workers discovered that droplets walking on a vibrating bath posses certain features previously thought to be exclusive to quantum systems. These millimetric droplets synchronize with their Faraday wavefield, creating a macroscopic pilot-wave system. In this talk we exploit the fact that the waves generated are nearly monochromatic and propose a hydrodynamic model capable of capturing the interaction between bouncing drops and a variable topography. We show that our model is able to reproduce some important experiments involving the drop-topography interaction, such as non-specular reflection and single-slit diffraction.

  19. O que é Interdisciplinaridade?

    Directory of Open Access Journals (Sweden)

    Nali Rosa Silva Ferreira

    2009-08-01

    Full Text Available RESUMO:O livro “O que é interdisciplinaridade?” organizado pela professora Ivani Fazenda é uma publicação da Cortez Editora, em 2008, e enfoca a interdisciplinaridade no currículo e na formação de professores. Está apresentado em treze capítulos e contou com a participação dos autores: Abdelkrim Hasni, Adriana Alves, Anderson Araújo-Oliveira, Diamantino F. Trindade, Dirce E. Tavares, Fernando César de Souza, Ivone Yared, Johanne Lebrun, Maria José Eras Guimarães, Mariana Aranha Moreira José, Raquel Gianolla Miranda, Ruy Cezar do Espírito Santo, Sonia Regina Albano de Lima, Yves Lenoir.PALAVRAS-CHAVE:Multidisciplinaridade; Interdisciplinaridades; CurrículoABSTRACT: The book "What is interdisciplinarity?" Organized by Professor Ivani Farm is published by Editora Cortez in 2008 and focuses on the interdisciplinary curriculum and teacher training. Is presented in thirteen chapters and was attended by the authors: Abdelkrim Hasni, Adriana Alves, Anderson Araújo-Oliveira, F. Diamond Trinity, Dirce E. Tavares, Fernando César de Souza, Ivone Yared, Johanne Lebrun, Maria José Guimarães Ages, Mariana Moreira Spider Joseph, Rachel Gianolla Miranda, Ruy Cezar the Holy Spirit, Sonia Regina Albano de Lima, Yves Lenoir. KEYWORDS: Multidisciplinary; Interdisciplinaridades; resumeRecebido: 29/06/2009       Aceito: 25/08/2009  

  20. PARTICLE-larly Enriching Night at CERN!

    CERN Multimedia

    Yves-Marie Ducimetière

    2010-01-01

    After the 2010 European Researchers' Night, a contest was organised for its participants, asking them to write about their experience. We are now pleased to announce the winner: Yves-Marie Ducimetière, a 14-year-old student at the Lycée International de Ferney-Voltaire.    Yves-Marie Ducimetière. The visit began for me around 20.30, as we all joined our respective groups to board a CERN shuttle to our final destination, which was LHCb in my case. I was heading into the unknown! On leaving, I knew nothing about this place, and the discovery made it all the more interesting. Upon arriving, a woman explained that their research looked at antimatter, or rather, the reason why it disappeared from our Universe – she then accompanied us inside. Amazingly, I found the place to be both friendly and serious. One physicist spoke passionately about the purpose of LHCb, in short: colliding particles in order to understand the Big Bang, the origin of t...

  1. O auto-respeito na escola Self-respect in school

    Directory of Open Access Journals (Sweden)

    Vera Lucia Trevisan de Souza

    2008-12-01

    Full Text Available Estudo com objetivo de identificar os valores presentes na escola e verificar quais interações favorecem a construção e ou a manutenção dos valores morais em particular o auto-respeito. Com enfoque teórico da Psicologia Socioistórica, a investigação apoiou-se nos estudos sobre moralidade de Jean Piaget e Yves de la Taille e constatou que coexistem na escola interações favorecedoras e não favorecedoras da construção de valores morais sendo que as últimas são mais freqüentes.This study aims at to identify the values found in school and to verify which interactions favor the construction and/or maintenance of moral values, especially self-respect. Departing from the theoretical approach of sociohistorical Psychology, the investigation is based on the studies on morality conducted by Jean Piaget and Yves de la Taille, and has come to the conclusion that interactions promoting and not promoting the construction of moral values coexist in school, the second being the most frequent.

  2. Quark Matter 2011 (QM11) Quark Matter 2011 (QM11)

    Science.gov (United States)

    2011-12-01

    International Advisory Committee Antinori, FedericoPaic, Guy Braun-Munzinger, PeterPajares, Carlos Cifarelli, LuisaPeitzmann, Thomas Erazmus, BarbaraRedlich, Krzysztof Eskola, KariRiccati, Lodovico Gaardhøje, Jens JørgenRoland, Gunther Gale, CharlesRoy, Christelle Gelis, FrancoisSchukraft, Jürgen Giubellino, PaoloSinha, Bikash Greiner, CarstenSrivastava, Dinesh Gyulassy, MiklosStachel, Johanna Harris, JohnSteinberg, Peter Hatsuda, TetsuoStroth, Joachim Heinz, UlrichSugitate, Toru Jacak, BarbaraTserruya, Itzhak Karsch, FrithjofVelkovska, Julia Kharzeev, DimaWang, Enke Kodama, TakeshiWang, Xin, Nian Lévai, PéterWessels, Johannes Manko, VladislavXu, Nu Müller, BerndtZajc, William Ollitrault, Jean-Yves Organizing Committee Arleo, FrancoisDupieux, Pascal Bastid, NicoleFurget, Christophe Bourgeois, Marie-LaureGranier de Cassagnac, Raphael Bregant, MarcoGuernane, Rachid Carminati, FedericoHervet, Carnita Castillo, JavierKuhn, Christian Cheynis, BrigitteOlivier, Nathalie Conesa, DelValle, Zaida Connor, MichelleRenshall, Lucy Crochet, PhilippeSuire, Christophe Delagrange, HuguesTihinen, Ulla Program Committee Schutz, Yves (Chair)Baldisseri, Alberto Wiedemann, Urs (co-Chair)Safarik, Karel Aurenche, Patrick

  3. Interfon

    CERN Multimedia

    Interfon

    2013-01-01

    www.interfon.fr Rendez-vous sur notre site pour toutes les « News » Interfon « News » « Nouveau partenaire chez Interfon » L’équipe de vente de la Direction des Opérations Internationales de Peugeot et Citroën vous accueillera le 13 juin de 10 h à 18 h à l’Holiday Inn de Thoiry autour d’un buffet Pour vous faire découvrir et essayer  les dernières nouveautés  Peugeot 2008 et 208 GTi, nouveau Citroën C4 Picasso... Présentez votre carte de sociétaire et profitez des conditions de vente préférentielles réservées aux fonctionnaires internationaux. Vos contacts Yves Moreau :   +33 (0)6 30 52 83 11 yves.moreau@mpsa.com Claude Paronneau :  +33 (0) 6  75 76 91 04 claude.paronneau@mpsa.com * * * * * Les 13, 1...

  4. Only noise if you can see. Spazi vuoti e luoghi dell'arte

    Directory of Open Access Journals (Sweden)

    Filippo Fimiani

    2014-07-01

    Full Text Available What happens to critical and aesthetic discourse when a painter promises that he will not paint anymore? What goes on when a famous artist says that all the paintings are just junk or dust, and all the institutional sites of the art-world – actually, the White cube of Clement Greemberg’s Modernism – are just wasted spaces? What’s the matter or the reason of the prestige of a similar no-working man, and what’s the perceptible quality of the value of a so-called art without any artefact at all? In the late '50sand early'60s in Paris, Andy Warhol and Yves Klein claimin different butvery similar ways the end of painting and the disappearing of the work of art from the exposition site and its becoming immaterial or environmental art, indiscernible within its surrounding living space and, finally, with the atmosphere of glamour and snobbish artist’s life. What kind of phenomenology, pragmatic, rhetoric, poetics, economy and ontology is possible when nospectatorialmode of visual consumption is any longer possible? What type of aesthetic relationship actually happens under these planned and produced conditions of non-perceptual and ‘artialized’ living experience? After more than fifty years, the statements of The philosophy of Andy Warhol and the Exposition of void of Yves Klein have not yet stopped to pose questions as such to aesthetics, theory of literature and critics, and to the history of art.

  5. Orienteering club

    CERN Multimedia

    Club d'orientation

    2011-01-01

    Coupe de printemps - les épreuves s’enchainent Le Club du CERN organisait la 4e étape de la coupe Genevoise de printemps samedi 9 avril. Tout était au rendez-vous pour une belle épreuve : soleil et nouvelle carte dans la forêt de Pougny-Challex. Les podiums des 5 parcours sont les suivants :   Facile court (2 km – 8 postes) : 1er Lucine Gintzburger en 29:01 - 2e Maria & Adèle Rapseviciute en 41:34 - 3e Emanuelle Alves en 41 :40. Facile moyen (2,9 km – 9 postes) : 1ere Konstantinos Haider (CO CERN) en 26:01 - 2e Joho en 34:41 - 3e Odysseas Willians/Jan Bleesz en 38:43. Technique court (3,2 km – 8 postes) : 1er Elisabeth Geneux en 32:08 - 2e Dominique Balay (CO CERN) en 33:59 - 3e Yves Meynet en 35:18. Technique moyen (4,9 km – 10 postes) : 1er Pierre-Yves Meyer en 47:04 - 2e Julien Nicolet en 50:06 - 3e Jean-Pierre Poncet en 50:42. Technique long (6,6 km &a...

  6. Building 887: An Aladdin's Cave for Physicists

    CERN Multimedia

    2001-01-01

    Building 887 on the Prévessin site is home to numerous experiments bringing together physicists and engineers from around the world. Its diversity makes the huge building a replica of CERN in miniature. The Installation unit of the SL EA group in front of the support structure for the ATLAS muon chambers. From left to right, seated: Pierre Gimenez, Yves Bonnet, Yves Naveau, Alain Pinget, Christian Becquet, Camille Adenot; standing: Philippe Guillot, Thierry Reynes, Monserrat Zurita-Perez, Claude Ferrari et Denis Gacon. The big wheel to be used for the ATLAS muon chambers (see below) is much the most spectacular installation currently occupying Building 887. But it is far from being the only attraction. Push open the heavy doors of this immense hall and it is a bit like entering a physicists' Aladdin's cave. The building, 55 metres wide and 300 metres long, is a treasure trove of engineering and technology, a CERN in miniature, housing dozens of collaborations from all over the world. With its 150...

  7. Porte : un dialogue par le livre. François Cheng et Claude Garanjoud

    Directory of Open Access Journals (Sweden)

    Sidona Bauer

    2011-07-01

    Full Text Available Cet article sur le dialogue par le livre a pour sujet l’échange entre le poète contemporain François Cheng (1929 Nanchang, Chine et le peintre lyrique abstrait Claude Garanjoud (1926 Isère – 2005 Lyon. Nous analysons le rapport entre les encres et les poèmes à travers un livre que les artistes ont réalisé en commun, Porte (1994, notamment à partir de leurs conceptions respectives des deux modes d’expression, la peinture et l’écriture étant considérés comme à égalité dans ce qu’on nomme un livre de dialogue (Yves Peyré.This article about the dialogue which can exist within a book on art, deals with the creative exchange between the contemporary poet François Cheng (1929 Nanchang, Chine and the painter Claude Garanjoud (1925 Isère – 2005 Lyon, who is considered to be a lyrical abstractionist. I analyse the relationship between two men as well as their two means of expression, poetry and ink painting – both equally strong in expression - in the so-called book-of-dialogue (Yves Peyré Porte (Door, 1994.

  8. A Quantum Annealing Computer Team Addresses Climate Change Predictability

    Science.gov (United States)

    Halem, M. (Principal Investigator); LeMoigne, J.; Dorband, J.; Lomonaco, S.; Yesha, Ya.; Simpson, D.; Clune, T.; Pelissier, C.; Nearing, G.; Gentine, P.; Fang, B.; Shehab, A.; Radov, Asen; Tikak, N.; Prouty, Roy; Harrison, Kenneth

    2016-01-01

    The near confluence of the successful launch of the Orbiting Carbon Observatory2 on July 2, 2014 and the acceptance on August 20, 2015 by Google, NASA Ames Research Center and USRA of a 1152 qubit D-Wave 2X Quantum Annealing Computer (QAC), offered an exceptional opportunity to explore the potential of this technology to address the scientific prediction of global annual carbon uptake by land surface processes. At UMBC,we have collected and processed 20 months of global Level 2 light CO2 data as well as fluorescence data. In addition we have collected ARM data at 2sites in the US and Ameriflux data at more than 20 stations. J. Dorband has developed and implemented a multi-hidden layer Boltzmann Machine (BM) algorithm on the QAC. Employing the BM, we are calculating CO2 fluxes by training collocated OCO-2 level 2 CO2 data with ARM ground station tower data to infer to infer measured CO2 flux data. We generate CO2 fluxes with a regression analysis using these BM derived weights on the level 2 CO2 data for three Ameriflux sites distinct from the ARM stations. P. Gentine has negotiated for the access of K34 Ameriflux data in the Amazon and is applying a neural net to infer the CO2 fluxes. N. Talik validated the accuracy of the BM performance on the QAC against a restricted BM implementation on the IBM Softlayer Cloud with the Nvidia co-processors utilizing the same data sets. G. Nearing and K. Harrison have extended the GSFC LIS model with the NCAR Noah photosynthetic parameterization and have run a 10 year global prediction of the net ecosystem exchange. C. Pellisier is preparing a BM implementation of the Kalman filter data assimilation of CO2 fluxes. At UMBC, R. Prouty is conducting OSSE experiments with the LISNoah model on the IBM iDataPlex to simulate the impact of CO2 fluxes to improve the prediction of global annual carbon uptake. J. LeMoigne and D. Simpson have developed a neural net image registration system that will be used for MODIS ENVI and will be

  9. Primary Sjögren syndrome: report of a 10 years old girl with local edema and positivity of anti SS-A and anti SS-B autoantibodies.

    Science.gov (United States)

    Shahi, E; Donati, C; Gattinara, M; Pontikaki, I; Gerloni, V

    2011-01-01

    Sjogren-Larsson syndrome (SLS) is an autoimmune disease, uncommon in childhood. We report a case of SLS in a 10-year-old girl with a history of tumor, calor and rubor in the back of her toes almost every month, which resolved in 4-5 days without therapy. She did not complain of dry mouth or dry eyes. The laboratory findings showed high inflammation markers, rheumatoid factor 128 IU, Waaler-Rose 256 IU, anti nuclear antibody (ANA) 1/640, SSA (anti Sjogren antigen A) and SSB (anti Sjogren antigen B) positive and hypergammaglobulinemia. The Schirmer's test resulted to be pathologic, the ultrasonography images and biopsy of minor salivary glands revealed focal periductal lymphocytic infiltrate and sialoduct ectasia class IV of juvenile Sjogren syndrome. The juvenile Sjogren syndrome is frequently under-diagnosed. Clinical manifestations in children might be different from the adult form, although laboratory findings may be similar to those found in adults.

  10. Utilidad de las ecuaciones basadas en la concentración sérica de cistatina C en el estudio de la función renal Usefulness of equations based on serum cystatin C concentration in the study of renal function

    Directory of Open Access Journals (Sweden)

    Carlos Chiurchiu

    2007-04-01

    Full Text Available La creatinina sérica es un marcador poco sensible para identificar reducciones leves del índice de filtración glomerular (IFG; por ello resulta de gran importancia clínica disponer de métodos alternativos para estimar la función renal. Con este objetivo estudiamos la función renal de 41 pacientes -grupo completo y divididos según la creatinina sérica (≤ 1.2 mg/dl o mayores- usando el clearance de creatinina modificado con cimetidina (Clcrc como aproximación al IFG, las ecuaciones de Larsson y Hoek que incluyen el uso de cistatina C sérica y las tradicionales fórmulas de Cockroft-Gault y MDRD abreviada. En el grupo completo de pacientes y especialmente en aquellos con creatinina sérica ≤1.2 mg/dl -con reducción de la función renal: Clcrc: 62.01 ± 17.33 ml/min/1.73 m²-, las ecuaciones de Larsson y Hoek mostraron mejores correlaciones y menores diferencias promedio respecto a las fórmulas basadas en la creatinina sérica. La ecuación MDRD abreviada mostró buen rendimiento sólo en el grupo con evidente alteración de la función renal (creatinina sérica > 1.2 mg/dl. Concluimos que en pacientes con diferentes estadios de función renal, las fórmulas que emplean la cistatina C sérica detectan la reducción del IFG más precozmente respecto a aquellas basadas en la creatinina sérica.Serum creatinine is an insensitive marker to identify early changes in glomerular filtration rate (GFR, for this reason alternative methods to estimate renal function result of great clinical importance. Forty-one patients were studied using creatinine clearance modified with cimetidina (Clcrc as surrogate of GFR, cystatin C-based equations (i.e. Larsson and Hoek formulas, Cockroft-Gault and MDRD abbreviated equations. In the whole group, as well as in those patients with serum creatinine ≤1.2 mg/dl -but reduced renal function: Clcrc 62.01 ± 17.33 ml/min/1.73 m²-, Larsson and Hoek equations showed higher correlations and lower bias than

  11. IMS部署条件成熟爱立信助运营商步入融合时代

    Institute of Scientific and Technical Information of China (English)

    舒文琼

    2006-01-01

    @@ 在电信网向下一代网络演进的过程中,IMS(IP多媒体子系统)像一匹突然杀出的黑马,一夜之间引起了人们的普遍关注.在国外,西班牙电信、沃达丰、Sprint等纷纷部署了IMS;在国内,关于IMS的讨论日渐升温.IMS的魅力何在,如何有效部署IMS?记者日前采访了爱立信(中国)通信有限公司IMS系统解决方案总监罗信(Anders Larsson)先生.

  12. A short history of neuroendocrine tumours and their peptide hormones.

    Science.gov (United States)

    de Herder, Wouter W; Rehfeld, Jens F; Kidd, Mark; Modlin, Irvin M

    2016-01-01

    The discovery of neuroendocrine tumours of the gastrointestinal tract and pancreas started in 1870, when Rudolf Heidenhain discovered the neuroendocrine cells, which can lead to the development of these tumours. Siegfried Oberndorfer was the first to introduce the term carcinoid in 1907. The pancreatic islet cells were first described in 1869 by Paul Langerhans. In 1924, Seale Harris was the first to describe endogenous hyperinsulinism/insulinoma. In 1942 William Becker and colleagues were the first to describe the glucagonoma syndrome. The first description of gastrinoma by Robert Zollinger and Edwin Ellison dates from 1955. The first description of the VIPoma syndrome by John Verner and Ashton Morrison dates from 1958. In 1977, the groups of Lars-Inge Larsson and Jens Rehfeld, and of Om Ganda reported the first cases of somatostatinoma. But only in 2013, Jens Rehfeld and colleagues described the CCK-oma syndrome. The most recently updated WHO classification for gastrointestinal neuroendocrine tumours dates from 2010.

  13. X-Ray Heating of the Ejecta of Supernova 1987A

    Science.gov (United States)

    Sonneborn, George; Larsson, Josefin; Fransson, Claes; Kirshner, Robert; Challis, Peter; McCray, Richard

    2012-01-01

    Analysis of Hubble Space Telescope Band R band images from 1994 to 2009 show that the optical luminosity of SN 1987A has transitioned from being powered by radioactive decay of Ti-44 to energy deposited by X-rays produced as the ejecta interacts with the surrounding material (Larsson et al. 2011, Nature, 474, 484). The B and R band flux from the densest, central parts of the ejecta followed the expected exponential decline until 2001 (about day 5000) when the flux in these bands started increasing, more than doubling by the end of 2009. This increase is the result of heat deposited by X-rays from the shock interaction of the fast-moving outer ejecta with the inner circumstellar ring. In time, the X-rays will penetrate farther into the ejecta, enabling us to analyze the structure and chemistry of the vanished star.

  14. Tócala otra vez, Lisbeth. Estudio narratológico y semiótico de Millenium, un caso reciente de remake cinematográfico

    OpenAIRE

    Tropea Pompeu, Valentina

    2014-01-01

    Aquest treball consta de tres etapes. Les dues primeres indaguen sobre el fenomen del remake i les metodologies d'anàlisis fílmic de tipus narratològic i semiòtic. La tercera és un estudi comparatiu sobre un cas recent i complex: The Girl with the Dragoon Tatoo. Aquest és el remake nord-americà, del cèlebre director D. Fincher, d'un film suec, adaptació cinematogràfica de Millenium, la reeixida obra policíaca del suec Stieg Larsson. Aquest treball ens ha permès constatar com el remake, tan po...

  15. 故事,是从隐瞒开始

    Institute of Scientific and Technical Information of China (English)

    其里

    2010-01-01

    《龙文身的女孩》[瑞典]斯蒂格·拉森人民文学出版社作者简介:斯蒂格·拉森(Stieg Larsson),瑞典作家与新闻记者。曾任职于瑞典中央新闻通讯社,并于工作之余投身反法西斯主义的活动。1995年,他创办了Expo基金会,并1999年开始担任基金会同名杂志主编。由于他长期致力于揭发瑞典极右派组织的不法行为,多年来一直受到程度或轻或重的死亡恐吓与威胁。

  16. Coal consumption and economic growth: Evidence from a panel of OECD countries

    Energy Technology Data Exchange (ETDEWEB)

    Nicholas Apergis; James E. Payne [University of Piraeus, Piraeus (Greece). Department of Banking and Financial Management

    2010-03-15

    This study examines the relationship between coal consumption and economic growth for 25 OECD countries within a multivariate panel framework over period 1980-2005. The Larsson et al. (2001) panel cointegration test indicates there is a long-run equilibrium relationship between real GDP, coal consumption, real gross fixed capital formation, and the labor force. The respective coefficients for real gross fixed capital formation and the labor force are positive and statistically significant whereas the coefficient for coal consumption is negative and statistically significant. The results of the panel vector error correction model reveal bidirectional causality between coal consumption and economic growth in both the short- and long-run; however, the bidirectional causality in the short-run is negative. 31 refs., 5 tabs.

  17. The origin of the Mendelian Society in Lund and the start of Hereditas.

    Science.gov (United States)

    Höglund, Mattias; Bengtsson, Bengt O

    2014-12-01

    The Mendelian Society in Lund was founded in 1910. The initiative came from two young biologists supported by a wide circle of interested plant breeders and academics. Already from the start the society was dominated by the towering personality Herman Nilsson-Ehle. After two active years, the Society went into temporal hibernation until it resumed its activities in spring 1916, when Nilsson-Ehle was on his way to become Sweden's first professor of genetics. One of the aims of the Society was to launch a scientific journal for local scientists directed at an international audience. After a successful fundraising campaign, Hereditas was started in 1920. One of the original instigators of the Mendelian Society, Robert Larsson, became its first editor, and he remained in this position for more than 30 years. Both he and Nilsson-Ehle were fascinating personalities, deeply rooted in their time's scientific and ideological debates. © 2014 The Authors.

  18. From Creep to Co-op: Research(er Paying the Cost of Discplacement?

    Directory of Open Access Journals (Sweden)

    Joakim Forsemalm

    2013-09-01

    Full Text Available As discussed by planning researchers Jalakas & Larsson (2008, in Sweden, socie-tal issues such as social sustainability, urban life and gender fails to travel from comprehensive documents in the urban planning system to the legislative ones (i.e. the “detailed development plans”. This might, as this essay argues, have to do with the absence of “cultural brokers”, i.e a kind of translator of the narratives told in a particular society. Can researchers act as such translators – increasing the pre-cence of cultural and everyday-life experiences in legislative planning documents? This essay discusses problems and possibilities with an ethnography engageing with/in society.

  19. Use of cystatin C and serum creatinine for the diagnosis of contrast-induced nephropathy in patients undergoing contrast-enhanced computed tomography at an oncology centre.

    Directory of Open Access Journals (Sweden)

    Joao Italo Fortalesa Melo

    Full Text Available Our aim was to assess renal function using as laboratory measurements serum creatinine and cystatin C concentrations before and after administration of low-osmolarity (nonionic iodinated contrast medium in patients with cancer undergoing computed tomography (CT.This prospective study included 400 oncologic outpatients. Serum creatinine and cystatin C concentrations were measured before and 72 h after contrast administration. Glomerular filtration rates (GFRs were estimated using serum creatinine-based [Modification of Diet in Renal Disease (MDRD and Cockroft-Gault and cystatin C based (Larsson equations. Exploratory data analysis was performed. The nonparametric Wilcoxon test was used to compare pre and post contrast of test results and estimated clearance. The confidence interval used in the analysis was 95%.Compared with the pre-contrast values, the mean serum creatinine concentration was significantly higher and average GFRs estimated using MDRD and Cockcroft-Gault equations were significantly lower after the administration of contrast (p <0.001. It was also observed a significant increase after contrast in the concentration of Cystatin C (p = 0.015. In addition, a decrease in GFR estimated using the average Larsson (p = 0.021 was observed between time points. However, none of the patients presented clinically significant nephropathy.Assessment using serum creatinine and cystatin C concentrations showed changes in renal function among patients with cancer undergoing contrast-enhanced CT examination in this study. No significant renal damage related to the use of low-osmolarity iodinated contrast medium of the type and dosage employed in this study was observed. This contrast medium is thus safe for use in patients with cancer.

  20. Use of Cystatin C and Serum Creatinine for the Diagnosis of Contrast-Induced Nephropathy in Patients Undergoing Contrast-Enhanced Computed Tomography at an Oncology Centre

    Science.gov (United States)

    Fortalesa Melo, Joao Italo; Chojniak, Rubens; Costa Silva, Debora Helena; Oliveira Junior, Jose Carlos; Vieira Bitencourt, Almir Galvão; Holanda Silva, Diego; Guimarães, Marcos Duarte; Silva, Hernandes Cerqueira Souza; Dias, Denis Guilherme Teixeira; Rodrigues, Winglison Carli; Brancucci, Ellen Luzia; Cruz, Barbara Martins Soares; Schiavon, Beatriz Nunes; Argenton, Juliana Luz Passos; Camporini, Margareth Arrivabene; Zocchio, Adriana

    2015-01-01

    Objective Our aim was to assess renal function using as laboratory measurements serum creatinine and cystatin C concentrations before and after administration of low-osmolarity (nonionic) iodinated contrast medium in patients with cancer undergoing computed tomography (CT). Methods This prospective study included 400 oncologic outpatients. Serum creatinine and cystatin C concentrations were measured before and 72 h after contrast administration. Glomerular filtration rates (GFRs) were estimated using serum creatinine–based [Modification of Diet in Renal Disease (MDRD) and Cockroft-Gault and cystatin C based (Larsson) equations. Exploratory data analysis was performed. The nonparametric Wilcoxon test was used to compare pre and post contrast of test results and estimated clearance. The confidence interval used in the analysis was 95%. Results Compared with the pre-contrast values, the mean serum creatinine concentration was significantly higher and average GFRs estimated using MDRD and Cockcroft-Gault equations were significantly lower after the administration of contrast (p <0.001). It was also observed a significant increase after contrast in the concentration of Cystatin C (p = 0.015). In addition, a decrease in GFR estimated using the average Larsson (p = 0.021) was observed between time points. However, none of the patients presented clinically significant nephropathy. Conclusions Assessment using serum creatinine and cystatin C concentrations showed changes in renal function among patients with cancer undergoing contrast-enhanced CT examination in this study. No significant renal damage related to the use of low-osmolarity iodinated contrast medium of the type and dosage employed in this study was observed. This contrast medium is thus safe for use in patients with cancer. PMID:25961558

  1. Probabilistic Contextuality in EPR/Bohm-type Systems with Signaling Allowed

    Science.gov (United States)

    Kujala, Janne V.; Dzhafarov, Ehtibar N.

    In this chapter, we review a principled way of defining and measuring contextuality in systems with deterministic inputs and random outputs, recently proposed and developed in Kujala, Dzhafarov and Larsson (2015); Dzhafarov, Kujala and Larsson (2015). We illustrate it on systems with two binary inputs and two binary random outputs, the prominent example being the system of two entangled spin-half particles with each particle's spins (random outputs) being measured along one of two directions (inputs). It is traditional to say that such a system exhibits contextuality when it violates Bell-type inequalities. Derivations of Belltype inequalities, however, are based on the assumption of no-signaling, more generally referred to as marginal selectivity: the distributions of outputs (spins) in Alice's particle do not depend on the inputs (directions chosen) for Bob's particle. In many applications this assumption is not satisfied, so that instead of contextuality one has to speak of direct crossinfluences, e.g., of Bob's settings on Alice's spin distributions. While in quantum physics direct cross-in uences can sometimes be prevented (e.g., by space-like separation of the two particles), in other applications, especially in behavioral and social systems, marginal selectivity almost never holds. It is unsatisfying that the highly meaningful notion of contextuality is made inapplicable by even slightest violations of marginal selectivity. The new approach rectifies this: it allows one to define and measure contextuality on top of direct cross-in uences, irrespective of whether marginal selectivity (no-signaling condition) holds. For systems with two binary inputs and two binary random outputs, contextuality means violation of the classical CHSH inequalities in which the upper bound 2 is replaced with 2(1 + Δ0), where Δ0 is a measure of deviation from marginal selectivity.

  2. Construction and Analysis of Electronic circuits

    Science.gov (United States)

    Thomas, Ashley N.

    2004-01-01

    The Aviation Environmental Technical Branch produces many various types of aeronautical research that benefits the NASA mission for space exploration and in turn, produces new technology for our nation. One of the present goals of the Aviation Environmental Technical Branch is to create better engines for airplanes by testing supersonic jet propulsion and safe fuel combustion. During the summer of 2004, I was hired by Vincent Sattenvhite Chief executive of the Aviation Environmental Technical Branch to Assist Yves Lamothe with a fuel igniter circuit. Yves Lamothe is an electrical engineer who is currently working on safe fuel combustion testing. This testing is planned to determine the minimum ignition energy for fuel and air vapors of current and alternative fuels under simulated flight conditions. An air temperature bath will provide simulated flight profile temperatures and the heat fluxes to the test chamber. I was assigned with Yves to help complete the igniter circuit which consists of a 36k voltage supply an oscilloscope, and a high voltage transistor switch. During my tenure in the L.E.C.I.R.P. program I studied the basics of electricity and circuitry along with two other projects that I completed. In the beginning of my internship, I devote all of my time to research the aspects of circuitry so that I would be prepared for the projects that I was assigned to do. I read about lessons on; the basic physical concepts of electronics, Electrical units, Basic dc circuits, direct current circuit analysis, resistance and cell batteries, various types of magnetism , Alternating current basics, inductance, and power supplies. I received work sheets and math equations from my Mentor so that I could be able to apply these concepts into my work. After I complete my studies, I went on to construct a LED chaser circuit which displays a series of light patterns using a 555 timer. I incorporated a switch and motion detector into the circuit to create basic alarm system

  3. PREFACE: Nanosafe 2012: International Conferences on Safe Production and Use of Nanomaterials

    Science.gov (United States)

    Tardif, François

    2013-04-01

    Welcome from the organizers The rapidly developing field of nanotechnology opens up many exciting opportunities and benefits for new materials with significantly improved properties as well as some revolutionary applications in the fields of energy, environment, medicine, etc. These new materials potentially pave the way to considerable innovations in many industries of the 21st century although associated risks must be perfectly under control for workers, consumers and the environment. So, one can easily understand why Nanosafety is now considered as a specific new scientific area, gaining in importance and maturity every day. Following the successful outcome of the two past international conferences on the safe production and use of nanomaterials: Nanosafe 2008 and 2010, the organizing committee has the pleasure of welcoming again to Grenoble some of the most famous specialists of the field in the world. In addition to the standard issues addressed in previous nanosafe conferences such as Toxicology, Eco-toxicology, Expology, Detection, Life Cycle Analysis, Regulation and Standardization, new topics of great interest will be dealt with this year, concerning Governance and practical Risk Management for OSH experts and Societal issues. In order to enhance the exchanges and conviviality three debates werw organized around Nano Governance, Toxicology and Ethics. We hope that you will appreciate this new Nanosafe edition like the previous ones. This is your Nanosafe conference, please enjoy. The Nanosafe conference organisers François Tardif and Frédéric Shuster Management Vanessa Gaultier Francois TardifFrederic ShusterVanessa Gaultier François TardifFrédéric Shuster Vanessa Gaultier Local Organizing Committee Vanessa GAULTIER (CEA) François TARDIF (CEA) Dominique BAGUET (CEA) Frédédric SHUSTER (CEA) Yves SICARD (CEA) Catherine DURAND (CEA) Didier MOLKO (MINATEC) International Scientific Committee Chair: Frédéric SCHUSTER (CEA, FR) François TARDIF (CEA

  4. CERN and UNESCO reach out to Rwanda

    CERN Multimedia

    2009-01-01

    CERN already has a successful relationship with some African countries. However, much remains to be done to improve the dialogue with that continent. A recent trip to Rwanda provided a new opportunity to share knowledge and technology and create a connection that may last for many years. CERN’s Jean-Yves Le Meur, second from the right, teaches participants how to install the digital library system on their computers.In addition to physics research, CERN’s key missions also include training and international collaboration. Recently, thanks to funding from UNESCO, CERN’s Scientific Information Service was able to provide face-to-face training of digital library software developed at CERN, and the CERN Education Group organised a two-day high-school teacher training programme. "Many African countries are in the process of digitising their libraries," explains John Ellis, CERN’s Coordinator for non-Member States. "A workshop was ...

  5. Delphine Corteel & Stephane Lelay (dirs, Les Travailleurs des déchets

    Directory of Open Access Journals (Sweden)

    Paul Bouffartigue

    2013-03-01

    Full Text Available Douzième titre de la jeune et remarquable collection dirigée par Yves Clot et Dominique Luillier, un ouvrage passionnant est publié par Érès autour de la figure paradigmatique du « sale boulot » : la collecte, la transformation et l’élimination des déchets. Qu’il soit « organique, végétal, animal ou humain », Alain Corbin nous rappelle dans la Préface qu’il « figure l’ordure par excellence, tout simplement parce qu’il traduit l’angoisse de la mort, celle que suscitent la vue et le contact de ...

  6. Savoir lire les centres historiques comme clé pour construire la ville de demain

    Directory of Open Access Journals (Sweden)

    Alexis Sierra

    2010-05-01

    Full Text Available Yves Dauge est sénateur d’Indre et Loire (membre de la commission de la culture, de l'éducation et de la communication, membre du groupe d'études sur le patrimoine architectural. Inspecteur général de l’équipement, ancien maire de Chinon, il a été délégué interministériel à la ville et au développement social urbain de 1988 à 1991. Il a conduit la délégation française au Vème Forum Urbain Mondial à Rio. Il anime avec les services du Ministère des Affaires Etrangères et Européennes, le nouvea...

  7. 精致的尸体

    Institute of Scientific and Technical Information of China (English)

    马修; 徐佳音(译)

    2009-01-01

    根据传说和可靠的历史记录,“精致的尸体”是一个在1925年诞生于一群法国诗人和艺术家之间的游戏。这个炫耀的群体中,有画家伊夫·唐吉(Yves Tanguy)、诗人安德烈·布勒东(Andre Breton)和雅克·普莱维尔(Jacques Prevert)。游戏在一个古老的客厅里开始,用来消磨时光和填补那些热烈讨论间隙的空白。

  8. CERN reveals its real nature

    CERN Multimedia

    2009-01-01

    CERN has been awarded an environmental label for its protection of rare flower species and its natural landscaping at the Meyrin site. Ophrys apifera, or bee orchid: the most widespread variety at our site. This year, a Himantoglossum robertianum or giant orchid was spotted for the first time, an extremely rare specimen to find in our region. The monkey orchid, Orchis simia, gets its name from the bizarre shape of its labellum (this is actually the third petal, hanging down from the flower), which may remind you of a monkey. Himantoglossum hircinum, the lizard orchid, occurs periodically on the site. It has a rather strong odour, which is why in French it is called orchis bouc (goat orchid). Yves Chevret and Michel Vauthey surrounded by Orchis pyramidal plants. It takes a tr...

  9. Staff Members with more than 25 years service at CERN in 2001 and 2002

    CERN Multimedia

    Maximilien Brice

    2002-01-01

    Staff Members with 25 years service in 2002 were invited by the Director-General to a reception in their honnor on the 20th November 2002 : Baulet Yves / ST, Bornand Michel / SL, Burdet Georges / ST, Carena Francesco / EP, Chanut Robert / LHC, Chauchaix Bruno / SL, Chevrier François / SL, Chohan Vinod / LHC, Dahlerup-Petersen Knud / LHC, De Gennaro Michele Silvano / IT, De Rujula Alvaro / TH, Dury Jean-Marie / SL, Ferrara Sergio / TH, Fraser Gordon / ETT, Kolly Michel / ST, Korda Gwendoline / DSU, Lager Michel / ST, Michelon Jean-Claude / SL, Montuelle Jean / IT, Naudi Andre John / FI, Seis Irene / IT, Vascotto Alessandro / EP, Vernamonte Donatino / ST, Von Rüden Wolfgang / IT, Vullierme Bruno / LHC. Staff members with 25 years service in 2001 were also invited: Datta-Cockerill Sudeshna / HR, Frost-Ainley Lio / IT, Laurent Moniek / HR, Saban Roberto / AC.

  10. La ''Alegría de leer'': cartilla escolar con estatus patrimonial. Conservación y nuevos modos de circulación de un lugar de memoria

    Directory of Open Access Journals (Sweden)

    Mary Luz Botero

    2014-09-01

    Full Text Available This reflection paper emerged from a meeting and a suggestive image in which several topics that have motivated some of my studies and research topics condense. Memory, uses of the past, creative flow of cultural beings, processes of heritage construction from a communication perspective, all those topics are stated there, the glass case carefully displays a special book: the fourth book of Alegría de leer by Evangelista Quintana. Based on the theoretical assumptions of Yves Jeanneret and Jean Davallon regarding ''patrimonialization'', the particular case of an object (this student handbook vested with resignifications revealing a missing past in the present is illustrated. The sentimental value given by societies to certain objects promotes the generation of preservation strategies and stimulates new circulation means aiming at creating materialities able to support collective memories.

  11. Staff Members with more than 25 years service at CERN in 2001 and 2002

    CERN Multimedia

    2002-01-01

    Staff Members with 25 years service in 2002 were invited by the Director-General to a reception in their honnor on the 20th November 2002 : Baulet Yves / ST Bornand Michel / SL Burdet Georges / ST Carena Francesco / EP Chanut Robert / LHC Chauchaix Bruno / SL Chevrier François / SL Chohan Vinod / LHC Dahlerup-Petersen Knud / LHC De Gennaro Michele Silvano / IT De Rujula Alvaro / TH Dury Jean-Marie / SL Ferrara Sergio / TH Fraser Gordon / ETT Kolly Michel / ST Korda Gwendoline / DSU Lager Michel / ST Michelon Jean-Claude / SL Montuelle Jean / IT Naudi Andre John / FI Seis Irene / IT Vascotto Alessandro / EP Vernamonte Donatino / ST Von Rüden Wolfgang / IT Vullierme Bruno / LHC Staff members with 25 years service in 2001 were also invited: Datta-Cockerill Sudeshna / HR Frost-Ainley Lio / IT Laurent Moniek / HR Saban Roberto / AC

  12. Using Video Analysis, Microcomputer-Based Laboratories (MBL’s and Educational Simulations as Pedagogical Tools in Revolutionizing Inquiry Science Teaching and Learning

    Directory of Open Access Journals (Sweden)

    Jay B. Gregorio

    2015-01-01

    Full Text Available La main á la pâte is an inquiry-based science education programme founded in 1996 by Georges Charpak, Pierre Lena, Yves Quere and the French Académie des Sciences with the support of the Ministry of Education. The operation of the program primarily aims to revitalize and expand science teaching and learning in primary education by implementing an inquiry process that combines spontaneous exploration through varied prediction, experimentation, observation and argumentation. As a recognized program of innovation in science, La main á la pâte has gained global visibility and transcended across cultural backgrounds. The strength of the program is founded on continuous educational collaboration and innovative projects among pioneering institutions and educators for more than a decade.

  13. Du géosystème au géoanthroposystème

    Directory of Open Access Journals (Sweden)

    Henri Reymond

    2009-12-01

    Full Text Available Je remercie Yves Guermond de réagir aux textes d’A. Berque ainsi qu’à mon dernier papier en les liant car ils procèdent du même esprit. Il pense qu’ils demandent réflexion et il forcent cette dernière. Je vais répondre en détail aux questions pertinentes qu’il pose après cependant avoir contesté l’usage qu’il fait des expressions « pirouette intellectuelle » et « chape idéologique » qui se renforçant l’une l’autre annihilent le débat scientifique avant même qu’on puisse le penser. Doute scien...

  14. The First "lost" International Conference on Nonlinear Oscillations (I.C.N.O.)

    CERN Document Server

    Ginoux, Jean-Marc

    2014-01-01

    From 28 to 30 January 1933 was held at the Institut Henri Poincar\\'{e} (Paris) the first International Conference of Nonlinear Oscillations organized at the initiative of the Dutch physicist Balthazar Van der Pol and of the Russian mathematician Nikola\\"{i} Dmitrievich Papaleksi. The discovery of this forgotten event, whose virtually no trace remains, was made possible thanks to the report written by Papaleksi at his return in USSR. This document has revealed, one the one hand, the list of participants who included French mathematicians: Alfred Li\\'{e}nard, \\'{E}lie and Henri Cartan, Henri Abraham, Eug\\`{e}ne Bloch, L\\'{e}on Brillouin, Yves Rocard, ... and, on the other hand the content of presentations and discussions. The analysis of the minutes of this conference presented here for the first time highlights the role and involvement of the French scientific community in the development of the theory of nonlinear oscillations.

  15. Le poids de l'apparence dans le monde noir. Un héritage africain à l'heure de la globalisation aux États-Unis

    OpenAIRE

    Berloquin-Chassany, Pascale

    2005-01-01

    Mon travail de thèse de doctorat en sociologie s’est orienté plus concrètement lors du premier Festival International de la Mode Africaine, en novembre 1998. Aux portes du désert de l’Aïr au Niger, Alphadi avait invité des confrères originaires de son continent, mais également Kenzo et Isey Miaké et nombre de collections d’Yves Saint-Laurent, de Trussardi et de Christian Lacroix, entre autres. La présence du maire de Washington et autres personnalités des États-Unis me conduisit de l'autre cô...

  16. 修复光阴 钟表修复师能将藏品从岁月的痕迹和人为的耗损中解放出来

    Institute of Scientific and Technical Information of China (English)

    樊婧

    2012-01-01

    作为一名钟表修复大师,米歇尔·帕马强尼具有出众的天赋,以至于早在上世纪70年代,初出茅庐就破瑞士著名收藏家乔宾看重,将一系列山度士(Maurice-Yves Sandoz)收藏品的重任交付于他,他因此接触到历史上的钟表珍品,并因此与山度士家族基金会结缘,后者促成了帕马强尼品牌的创立。

  17. Du statut au contrat : vers une fonction publique “déstatufiée” ?

    OpenAIRE

    2014-01-01

    International audience; Le statut général de la fonction publique est octroyé par la loi générale2 et par des décrets d’application et des décrets portant statut particulier des différents corps ou cadres d’emplois. Pareil légalisme porte un objectif pratique clair : rendre applicable un droit dérogatoire au droit commun, le droit commun du travail en particulier. Il est la conséquence logique, comme l’exposait le député Yves Fagon devant l’Assemblée nationale constituante dans son rapport su...

  18. USE OF THE PICNIC AREA

    CERN Multimedia

    Relations with the Host States Service

    2001-01-01

    On the Prévessin site CERN has provided a picnic area which is available for use by persons working on its site subject to prior reservation. The person in charge of this picnic area is Mr Yves CHEVRET ST/TFM. Following a fresh outbreak of incidents (damage to CERN equipment and to trees and plants, privately owned sheep killed or maimed by dogs belonging to users of the picnic area, etc.),   The following measures have been taken: a report on the state of the picnic area will be drawn up before and after use, the cost of any damage noted will be borne by the person making the reservation, dogs and other domestic animals are strictly forbidden in the picnic area.

  19. Different Points of View Concerning the Didactic Transposition

    Directory of Open Access Journals (Sweden)

    Késia Caroline Ramires Neves

    2011-10-01

    Full Text Available The present article treats the concept of Didactic Transposition, taking as reference the work of Yves Chevallard, La transposición didáctica: del saber sabio al saber enseñado (2005. We compared the adduction of the concept in several works, such as thesis, dissertations and articles, and discussed the multiple impressions concerning the process of didactic transposition. These papers show that the conceptualizations are not well defined, entailing dubiousness and discussions. Some differences accrue from different areas of science, distinct of mathematics, others are inherent on the original ideas in Chevallard (2005, paper that served as bibliographical reference for the majority of the studied works.

  20. Epistemological and Ontological Paraconsistency in Quantum Mechanics: For and Against Bohrian Philosophy

    CERN Document Server

    de Ronde, Christian

    2014-01-01

    We interpret the philosophy of Niels Bohr as related to the so called "linguistic turn" and consider paraconsistency in the light of the Bohrian notion of complementarity. Following [16], Jean-Yves Beziau has discussed the seemingly contradictory perspectives found in the quantum mechanical double slit experiment in terms of paraconsistent view-points [7, 8]. This interpretation goes in line with the well known Bohrian Neo-Kantian epistemological account of quantum mechanics. In the present paper, we put forward the idea that one can also consider, within quantum mechanics and departing from the philosophy of the danish physicist, a more radical paraconsistency found within one of the main formal elements of the theory, namely, quantum superpositions. We will argue that, rather than epistemological, the contradictions found within quantum superpositions could be interpreted as ontological contradictions.

  1. Distinguishing the Sciences: For Nursing

    Directory of Open Access Journals (Sweden)

    Catherine Green

    2014-06-01

    Full Text Available The article explores the problem of nursing as a practical discipline and suggests that there are several kinds of nursing science. Following the lead of Jacques Maritain and Yves R. Simon, the authoress begins with an account of the distinguishing characteristics of theoretical knowledge, to which the term “science” has historically been applied, and distinguishes it from practical knowledge or prudence. Next she reviews Maritain and Simon’s discussion of two intermediate levels of inquiry that share some characteristics of both science and practical knowledge. Finally, using the writings of several nurse theorists whose seminal ideas in this area have established a basis for nurse theorist’s discussion of these issues, she distinguishes four kinds of nursing inquiry which range from the very theoretical to the very practical.

  2. Introduction of the Nobel Prize in Chemistry 2005%2005年诺贝尔化学奖成果简介

    Institute of Scientific and Technical Information of China (English)

    朱玉军; 王香凤

    2005-01-01

    2005年诺贝尔化学奖授予在烯烃复分解合成转换方面做出重要贡献的3位科学家:Yves Chauvin,Richard R. Schrock和Robert H. Grubbs.简要介绍了3位获奖者的主要贡献,烯烃复分解反应的分类和催化反应机理,金属卡宾催化剂及烯烃复分解反应的一些应用.另外,介绍了此领域目前研究的主要科学问题.

  3. The chaotic interaction of two walkers

    Science.gov (United States)

    Tadrist, Loic; Samara, Naresh; Schlagheck, Peter; Gilet, Tristan

    2016-11-01

    A droplet bouncing on a vertically vibrated bath may be propelled horizontally by the Faraday waves that it generates at each rebound. This association of a wave and a particle is called a walker. Ten years ago, Yves Couder and co-workers noted that the dynamical encounter of two walkers may lead to either scattered trajectories or orbital motion. In this work, we investigate the interaction of two walkers more systematically. The walkers are launched towards each other with finely controlled initial conditions. Output trajectories are classified in four types: scattering, orbiting, wandering and complex. The interaction appears stochastic: the same set of initial parameters (to the measurement accuracy) can produce different outputs. Our analysis of the underlying chaos provides new insights on the stochastic nature of this experiment. This work is supported by the ARC Quandrops of the Wallonia-Brussels Federation.

  4. What's new @CERN ? n°2

    CERN Multimedia

    CERN video productions

    2011-01-01

    30 March 2010 – a milestone for the Large Hadron Collider, the most powerful particle accelerator in the world.On this day the LHC started up at unprecedented energy levels. Since then, particle collisions continue to occur in the detectors and their analysis holds promises for new physics discoveries. In this edition of What’s new at CERN, we will report on the performance of this machine and talk about how its operating mode will change in a few days. The keywords for today? Performance – magnets – experiments – ions - protons – the future Today we are joined by, Steve Myers, Director for Accelerators and Technology, and Yves Schutz, Physicist in the ALICE experiment. By the way François and Stéphan, where are you?

  5. Gregory Bateson e o processo comunicativo

    Directory of Open Access Journals (Sweden)

    Lígia Campos de Cerqueira Lana

    2008-12-01

    Full Text Available Em busca de proposições para a definição do conceito de comunicação, este artigo apresenta a revisão de dois trabalhos de Gregory Bateson: Communication, the social matrix of psychiatry, de 1965, em co-autoria com Jurgen Ruesch e Communication, de 1971, capítulo de abertura da obra coletiva The natural history of an interview. Conforme Yves Winkin, o trabalho de Bateson situa-se no modelo orquestral da Comunicação, que postula a circularidade e a complexidade dos processos comunicativos. Gregory Bateson, com sua formação interdisciplinar, traz contribuições importantes para a compreensão do caráter interativo da comunicação, bem como para a definição de seu estatuto enquanto disciplina fundamental para a compreensão da vida social.

  6. Přátelská kritika církve a její reforma

    Directory of Open Access Journals (Sweden)

    Ondřej Salvet

    2017-08-01

    Full Text Available This article discusses the possibility of reform that is church-friendly, and to that end engages in a brief historical analysis of relevant historical periods (Gregorian reform, German reformation, Church renewal in 20th century. The decisive thought of Yves Congar is presented as a significant expansion of the corpus of thought on Church reform by his not so well known fellow friars. Their conclusion was that the Church can only be reformed from within the Church, and through the Church. Thus, the idea of reform is not an unwelcome novelty. Instead, both the Church and the tradition of reforming thought might be seen as two aspects of unique mystery, namely of God’s dwelling among his people.

  7. Offshore oil: costs and benefits. [Pamphlet

    Energy Technology Data Exchange (ETDEWEB)

    Bradley, T.; Byrne, B.; Cousteau, J.Y.; Haynes, H.; Hughes, R.

    1976-01-01

    This pamphlet provides the edited transcript of a Round Table that concluded AEI's two-day conference on the impact of offshore oil, held at Los Angeles, California, in March 1975. The participants were Governor Brendan Byrne of New Jersey, representing the eastern coastal states governors, Captain Jacques-Yves Cousteau for the environmentalists, Chairman of the Board H. J. Haynes of Standard Oil of California for the oil companies, and Assistant Secretary Royston Hughes, representing the Department of the Interior and the administration generally. The moderator was Mayor Tom Bradley of Los Angeles. Regulations regarding the leasing of offshore sites and the impact of energy conservation on energy supplies are summarized. (MCW)

  8. Analysis of Returned Comet Nucleus Samples

    Science.gov (United States)

    Chang, Sherwood

    1997-12-01

    This volume contains abstracts that have been accepted by the Program Committee for presentation at the Workshop on Analysis of Returned Comet Nucleus Samples, held in Milpitas, California, January 16-18, 1989. Conveners are Sherwood Chang (NASA Ames Research Center) and Larry Nyquist (NASA Johnson Space Center). Program Committee members are Thomas Ahrens (ex-officio; California Institute of Technology), Lou Allamandola (NASA Ames Research Center), David Blake (NASA Ames Research Center), Donald Brownlee (University of Washington, Seattle), Theodore E. Bunch (NASA Ames Research Center), Humberto Campins (Planetary Science Institute), Jeff Cuzzi (NASA Ames Research Center), Eberhard Griin (Max-Plank-Institut fiir Kemphysik), Martha Hanner (Jet Propulsion Laboratory), Alan Harris (Jet Propulsion Laboratory), John Kerrid-e (University of Califomia, Los Angeles), Yves Langevin (University of Paris), Gerhard Schwehm (ESTEC), and Paul Weissman (Jet Propulsion Laboratory). Logistics and administrative support for the workshop were provided by the Lunar and Planetary Institute Projects Office.

  9. Les nouveaux horizons de l’ecclésiologie médiévale. Ecclésiologie et hérésiologie (Moyen Âge, Temps modernes

    Directory of Open Access Journals (Sweden)

    Dominique Iogna-Prat

    2010-10-01

    Full Text Available Le Père Yves Congar, auquel l’une des journées du cycle les «Nouveaux horizons de l’ecclésiologie» a été consacrée l’an passé, a en bonne partie fondé son histoire de l’ecclésiologie sur le couple ecclésiologie/hérésiologie, notant le fait avéré que les grands tournants ecclésiologiques sont, au Moyen Âge, le plus souvent concomitants de graves crises internes – par exemple le Grand Schisme – ou de remises en cause venues de milieux «dissidents» – ou dénoncés et poursuivis comme tels. Les réf...

  10. Bibliometrics and research evaluation uses and abuses

    CERN Document Server

    Gingras, Yves

    2016-01-01

    The research evaluation market is booming. "Ranking," "metrics," "h-index," and "impact factors" are reigning buzzwords. Government and research administrators want to evaluate everything -- teachers, professors, training programs, universities -- using quantitative indicators. Among the tools used to measure "research excellence," bibliometrics -- aggregate data on publications and citations -- has become dominant. Bibliometrics is hailed as an "objective" measure of research quality, a quantitative measure more useful than "subjective" and intuitive evaluation methods such as peer review that have been used since scientific papers were first published in the seventeenth century. In this book, Yves Gingras offers a spirited argument against an unquestioning reliance on bibliometrics as an indicator of research quality. Gingras shows that bibliometric rankings have no real scientific validity, rarely measuring what they pretend to. Although the study of publication and citation patterns, at the proper scales...

  11. 胰岛素耐受与铁和肝脏的相关性

    Institute of Scientific and Technical Information of China (English)

    马桢林

    2001-01-01

    @@ 一个由Yves Deugnier领导的法国研究小组在1997年的一篇报道中描述了一种新的临床-病理性综合征,即原发性肝铁超负荷(HIO),其运铁蛋白饱和度正常,HLA(人类白细胞抗原,与遗传性血色素沉着症相关)A3基因型频率正常,而血清和肝脏的铁浓度与血清铁蛋白浓度升高不成比例地升高.

  12. The story of CERN : a 50 year journey to the Heart of Matter

    CERN Multimedia

    CERN/Mannmade Productions

    2004-01-01

    This film chronicles the story of CERN, the world's largest laboratory for studying the nature of matter. Using fascinating archive footage, interviews, stunning video and state-of-the-art computer generated images, it spans half a century, from the hopes and vision of CERN's founding fathers to the Laboratory's latest particule accelerator, the 27-km Large Hadron Collider. Intervention byHerwig Schopper CERN Director General 1981-88 Jack Steinberger Nobel prize for Physics 1988Robert Aymar General Director of CERNWolfgang Von Rueden Head of CERN Information TechnologyJohn Ellis Theoretical PhysicistManjit Dosanjh CERN Education and Technology TransferRolf LanduaExperimental PhysicistRichard Jacobsson Experimental PhysicistFabiola Gianotti Experimental PhysicistYves Schutz Experimental PhysicistAlavaro de Rujula Theoretical PhysicistProf. Peter Higgs Edinburgh University

  13. 2005诺贝尔化学奖--烯烃复分解反应的故事(从发现到发展)%2005 Nobel Prize in Chemistry--A Story about Olefin Metathesis (From Discovery to Development)

    Institute of Scientific and Technical Information of China (English)

    罗治斌; 戴立信

    2005-01-01

    今年的诺贝尔化学奖由三位有机化学家法国人Yves Chauvin,美国人Richard R.Schrock和Robert H.Grubbs分享,以表彰他们在发展烯烃复分解反应中做出的贡献.从20世纪50年代发现烯烃复分解反应以来,经过近半个世纪的努力,这个反应已经发展成为有机和高分子合成中的有力武器.今天,烯烃复分解反应广泛应用于化学化工,医药和高分子材料行业,在推动社会发展,改变人类生活中发挥重要的作用.

  14. Retours d'expériences: « Les applications pilotes du projet ENERGIC OD » : Surveillance du trait de côte

    OpenAIRE

    VILMUS, Thierry; Frézot, Olivier

    2016-01-01

    National audience; Animation et présentation du projet ENERGIC OD: • Yves RIALLANT, Délégué général de l'AFIGEOLes applications pilotes du projet: • ProxiSanté : Application d'analyse de l'accessibilité aux services de santé Thomas PORTIER, Depth France SAS • Surveillance du Trait de Côte Thierry VILMUS, BRGM • Intégration des données de capteurs dans les infrastructures de données géographiques François LEPRINCE, Alkante S.A.S • Le bruit dans ma ville-OnoMap Erwan BOCHER, CNRS / Judicaël PIC...

  15. Bidens meyeri (Asteraceae, Coreopsideae: a new critically endangered species from Rapa, Austral Islands

    Directory of Open Access Journals (Sweden)

    Vicki Funk

    2014-10-01

    Full Text Available Bidens meyeri (Asteraceae/Compositae is described and illustrated from Rapa, Austral Islands, (French Polynesia. This new species is presumed to be most closely related to Bidens saint-johniana from nearby Marotiri Island. Bidens meyeri may be distinguished from B. saint-johniana based on the length of the peduncle (3 cm versus 10 cm, apex of the inner involucral bracts (glabrous vs. puberulent, smaller leaves (2.0–2.3 cm vs. 5–6 cm, and the general smaller size of the new species. Known from less than 50 individuals and restricted to one remote location, Bidens meyeri falls into the IUCN Critically Endangered (CR category. The new species is named in honor of Dr. Jean-Yves Meyer, Délégation à la Recherche, Polynésie Française,

  16. Bidensmeyeri (Asteraceae, Coreopsideae): a new critically endangered species from Rapa, Austral Islands.

    Science.gov (United States)

    Funk, Vicki A; Wood, Kenneth R

    2014-01-01

    Bidensmeyeri (Asteraceae/Compositae) is described and illustrated from Rapa, Austral Islands, (French Polynesia). This new species is presumed to be most closely related to Bidenssaint-johniana from nearby Marotiri Island. Bidensmeyeri may be distinguished from Bidenssaint-johniana based on the length of the peduncle (3 cm versus 10 cm), apex of the inner involucral bracts (glabrous vs. puberulent), smaller leaves (2.0-2.3 cm vs. 5-6 cm), and the general smaller size of the new species. Known from less than 50 individuals and restricted to one remote location, Bidensmeyeri falls into the IUCN Critically Endangered (CR) category. The new species is named in honor of Dr. Jean-Yves Meyer, Délégation à la Recherche, Polynésie Française.

  17. Teaching activity, curriculum and fields of influence in classroom

    Directory of Open Access Journals (Sweden)

    Laura Cristina Vieira Pizzi

    2013-09-01

    Full Text Available The purpose of this article is to analyse teaching activity, from the perspective of Activity Clinic of Yves Clot (2010, focusing on the curriculum developed in classroom, considering the conditions of its realization, requirements, contingencies and crossings in everyday life. To approach the complexity of the curriculum we use the Simple Self-confrontation technique, which uses the filming as a primary means of data collection. The teacher in this study worked in 2nd grade in a public Municipal Elementary School of Maceió/AL, located on the outskirts. The prescriptive character of curriculum policy was not determinant in curricular activity of this teacher, compared to other subjective factors and other content and subjects that readjusted the curriculum, printing new developments and implications.

  18. PS overcomes two serious magnet failures

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Two magnets (no.'s 6 and 19)and a bus bar connection in the PS were found to be faulty during high-voltage tests at the end of the accelerator shutdown. A five-week repair schedule was quickly devised. A team of mechanics, technicians and engineers worked at full speed to replace the faulty magnets, succeeding in limiting the delay of the accelerators' spring start-up to two weeks. Pictured here are members of the PS team with the replacement no. 6 magnet. From left to right: In the back row, Frédéric Roussel (Transport DBS), Yves Bernard (Transport DBS), Luc Moreno (Cegelec), Thierry Battimanza (Transport DBS), Raymond Brown (AB/ABP), Thomas Zickler (AT/MEL); at the front, Steven Southern (AT/VAC), Thierry Gaidon (Brun & Sorensen), Philippe Vidales (Cegelec), Daniel Aubert (Cegelec), Jerome Cachet (Transport DBS), Jose Manual Gomes de Faria (AT/MEL), Eric Page (AT/VAC).

  19. Bouncing and walking droplets

    Science.gov (United States)

    Molacek, Jan; Bush, John

    2012-11-01

    Motivated by the hydrodynamic quantum analogue system of Yves Couder, we examine the dynamics of silicone oil drops bouncing on a vertically vibrating liquid bath. We report regime diagrams indicating the dependence of the vertical drop motion on the system parameters. A logarithmic spring model for the interface is developed, and provides new rationale for the regime diagrams. We further examine the spatio-temporal evolution of the standing waves created on the bath surface by repeated drop impacts. Measurement of the tangential coefficient of restitution of drops bouncing on a quiescent bath enables us to accurately determine all the major forces acting on the drop during flight and impact. By combining the horizontal and vertical dynamics, we thus develop a model for the walking drops that enables us to rationalize both the extent of the walking regime and the walking speeds. The model predictions compare favorably with experimental data in the parameter range explored.

  20. Le point de vue pris au mot

    OpenAIRE

    Andor, József; Angenot, Marc; Aptekman, Gilles Col et Jeanne; Bacchini, Fabio; Chanay, Hugues Constantin de; Debrenne, Michèle; Domènech, Montserrat Cunillera; Edeline, Francis; Forget, Danielle; Galatanu, Olga; Goltzberg, Stefan; Kálmán, György C.; Kleiber, Georges; Klinkenberg, Jean-Marie; Komlósi, László I.

    2016-01-01

    Ce volume dédié aux travaux de Pierre-Yves Raccah réunit les contributions de ceux qui utilisent ses concepts et valident ou respectent son modèle sur la Sémantique des Points de Vue, mais aussi de ceux qui, malgré leurs parcours divergents, reconnaissent que P-Y Raccah marque une étape importante de la grande aventure intellectuelle de la pensée théorique en matière de sémantique instructionnelle d’ordre argumentatif. Les études réunies ici, par leur diversité, sont représentatives non seule...

  1. And now, for the winners.

    CERN Multimedia

    Alizée Dauvergne

    2010-01-01

    The Computer Security Day held on 10 June was a success. There were eight presentations, with some forty people attending each session.     The presentation videos can be viewed on Indico. The computer security team’s new website is now up and running, with a wealth of useful information and advice. Go to http://cern.ch/Computer.Security.     The quiz attracted 130 participants, and the answers have now been posted on line! The quiz winners are: Lars Aprin, Richard Baud, Thibaut Bernard, Brice Copy, Daniele de Ruschi, Sébastien Gadrat, Amanda Garcia Munoz, Stephen Gowdy, Joni Hahkala, Joseph Izen, Ryszard Erazm Jurga, Jukka Klem, Danila Oleynik, Ian Pong, Pascal Serge Roguet, Jani Tapani Taskinen, Jan Therhaag, Yves Thurel, Adrian Vogel, Thomas White. Well done to all! If you haven’t done so already, you should soon be getting your prize (i.e. a book, a T-shirt or a bag, etc.).  

  2. International trade and waste and fuel managment issue, 2008

    Energy Technology Data Exchange (ETDEWEB)

    Agnihotri, Newal (ed.)

    2008-01-15

    The focus of the January-February issue is on international trade and waste and fuel managment. Major articles/reports in this issue include: A global solution for clients, by Yves Linz, AREVA NP; A safer, secure and economical plant, by Andy White, GE Hitachi Nuclear; Robust global prospects, by Ken Petrunik, Atomic Energy of Canada Limited; Development of NPPs in China, by Chen Changbing and Li Huiqiang, Huazhong University of Science and Technology; Yucca Mountain update; and, A class of its own, by Tyler Lamberts, Entergy Nuclear. The Industry Innovation articles in this issue are: Fuel assembly inspection program, by Jim Lemons, Tennessee Valley Authority; and, Improved in-core fuel shuffle for reduced refueling duration, by James Tusar, Exelon Nuclear.

  3. Géopolitique du terrorisme: les territoires de l'insécurité de la mondialisation

    Directory of Open Access Journals (Sweden)

    2009-10-01

    Full Text Available Ce petit livre constitue une synthèse intéressante sur une question d'actualité, qui s'insère parfaitement dans les thèmatiques de la géographie contemporaine.En introduction, l'auteur tente de définir la notion de «  géopolitiques » en se référant aux diverses acceptions du terme telles qu'elles apparaissent chez Philippe Moreau Defarges, Friedrich Ratzel, Jacques Ancel, Yves Lacoste, Hervé Couteau Bégarie, etc. Il retrace l'évolution du concept au cours des XXe et début du XXIe siècles. Il ...

  4. Trabalho em saúde em tempos de biopoder

    Directory of Open Access Journals (Sweden)

    Miguel Angelo Barbosa Maia

    2014-07-01

    Full Text Available Making reference to the theories of Yves Clot's Activity Clinic, Foucault and Agamben, we carry out a theoretical reflection on health care workers when they are crossed by contemporaneous Capitalism's inflection. By a concise historical analysis, we consider that the health care practices have favored to have the control over an abstract biological body and that they have been crossed by a market logic, that takes immediate effects both on the people who needs medical treatment and those whose jobs are to take care of them. Considering the work as creative activity, we bring this article to a close suggesting that the care of others can be the same as caring for oneself, as postulated by Foucault, a kind of resistance against the changing of the health care system in a biopower emblematic territory, where the value of one life is decided by a sovereign, as Agamben have said.

  5. A new Executive Committee for 2013

    CERN Multimedia

    Staff Association

    2012-01-01

    The Staff Council met Tuesday, December 4th in an ordinary session. In agreement with the Statutes of the CERN Staff Association the Staff Council had to elect the Executive Committee for  2013. As there were no elections to the Staff Council this year, Michel Goossens, outgoing president and unique candidate for that fonction, presented a list for the Executive Committee which is quite similar to that of 2012. Some people change functions: Céline Grobon becomes Vice-President, Marcel Aymon Secretary, and Lawrence Faisandel Treasurer. Philippe Trilhe is the new departmental delegate to EN Department. There are also three new coordinators for standing committees: Frédéric Galleazzi, Juan Jose Perez Garcia, and Yves Sillanoli. Michel then presented the 2013 programme to the Staff Council. At the end of his presentation Michel thanked all Staff Council delegates for their dedication and motivation throughout the year. He particularly thanked Marcel Aymon, one of the ...

  6. Mitochondrial DNA Unwinding Enzyme Required for Liver Regeneration | Center for Cancer Research

    Science.gov (United States)

    The liver has an exceptional capacity to proliferate. This ability allows the liver to regenerate its mass after partial surgical removal or injury and is the key to successful partial liver transplants. Liver cells, called hepatocytes, are packed with mitochondria, and regulating mitochondrial DNA (mtDNA) copy number is crucial to mitochondrial function, including energy production, during proliferation. Yves Pommier, M.D., Ph.D., of CCR’s Developmental Therapeutics Branch, and his colleagues recently showed that the vertebrate mitochondrial topoisomerase, Top1mt, was critical in maintaining mitochondrial function in the heart after doxorubicin-induced damage. The group wondered whether Top1mt might play a similar role in liver regeneration.

  7. Behind the Scenes: Costume Design for Television

    Directory of Open Access Journals (Sweden)

    Gamze Toylan

    2013-12-01

    Full Text Available There are many things you don’t know about 'The League of Gentlemen': Focusing on the award winning costume designer Yves Barre’s work for The League of Gentlemen (BBC, 1999-2002, this article explores the role of the costume designer in television production. Using an anthropological method that combines original interviews with Barre, Steve Pemberton (one of the writer/performers and Jon Plowman (the executive producer as well as second hand material such as DVD extras, the article provides insight into the show’s creative process. The underlying objective is to shed light on the costume design process – an understudied stage of television production.

  8. Staff members with 25 years' service at CERN in 2015

    CERN Multimedia

    HR Department

    2015-01-01

    The 30 staff members who have spent 25 years within CERN in 2015 were invited by the Director-General to a reception in their honour on 10 December.        Renaud Barillere EN   Edgar Birker  DG   Sergio Calatroni  TE   Paola Catapano  DG   Christophe  Delamare GS   Philippe Farthouat  PH   Roger Forty  PH   Yves Gaillard   TE   Clara Gaspar  PH   Jean-Christophe  Gayde  EN   Hubert   Gerwig PH   Simone  Giani PH   Jean-Pierre Granchelli  EN   Juan Guijarro  IT   Helene Haller  PH   John Harvey  PH   Vincenzo Innocente PH ...

  9. Diffraction and interference of walking drops

    Science.gov (United States)

    Pucci, Giuseppe; Harris, Daniel M.; Bush, John W. M.

    2016-11-01

    A decade ago, Yves Couder and Emmanuel Fort discovered a wave-particle association on the macroscopic scale: a drop can bounce indefinitely on a vibrating bath of the same liquid and can be piloted by the waves that it generates. These walking droplets have been shown to exhibit several quantum-like features, including single-particle diffraction and interference. Recently, the original diffraction and interference experiments of Couder and Fort have been revisited and contested. We have revisited this system using an improved experimental set-up, and observed a strong dependence of the behavior on system parameters, including drop size and vibrational forcing. In both the single- and the double-slit geometries, the diffraction pattern is dominated by the interaction of the walking droplet with a planar boundary. Critically, in the double-slit geometry, the walking droplet is influenced by both slits by virtue of its spatially extended wave field. NSF support via CMMI-1333242.

  10. Functional characterization of aromatic amino acid aminotransferase involved in 2-phenylethanol biosynthesis in isolated rose petal protoplasts.

    Science.gov (United States)

    Hirata, Hiroshi; Ohnishi, Toshiyuki; Ishida, Haruka; Tomida, Kensuke; Sakai, Miwa; Hara, Masakazu; Watanabe, Naoharu

    2012-03-15

    In rose flowers, 2-phenylethanol (2PE) is biosynthesized from l-phenylalanine (l-Phe) via phenylacetaldehyde (PAld) by the actions of two enzymes, pyridoxal-5'-phosphate (PLP)-dependent aromatic amino acid decarboxylase (AADC) and phenylacetaldehyde reductase (PAR). We here report that Rosa 'Yves Piaget' aromatic amino acid aminotransferase produced phenylpyruvic acid (PPA) from l-Phe in isolated petal protoplasts. We have cloned three full length cDNAs (RyAAAT1-3) of aromatic amino acid aminotransferase families based on rose EST database and homology regions. The RyAAATs enzymes were heterogeneously expressed in Escherichia coli and characterized biochemically. The recombinant RyAAAT3 showed the highest activity toward l-Phe in comparison with l-tryptophan, l-tyrosine, d-Phe, glycine, and l-alanine, and showed 9.7-fold higher activity with l-Phe rather than PPA as a substrate. RyAAAT3 had an optimal activity at pH 9 and at 45-55°C with α-ketoglutaric acid, and was found to be a PLP dependent enzyme based on the inhibition test using Carbidopa, an inhibitor of PLP-dependent enzymes. The transcript of RyAAAT3 was expressed in flowers as well as other organs of R. 'Yves Piaget'. RNAi suppression of RyAAAT3 decreased 2PE production, revealing the involvement of RyAAAT3 in 2PE biosynthesis in rose protoplasts and indicating that rose protoplasts have potentially two different 2PE biosynthetic pathways, the AADC route and the new route via PPA from l-Phe.

  11. Atti del convegno internazionale "Le problème de l' "altéritè" dans la culture européenne aux 18ème et 19ème siècles: anthropologie, politique et religion" ( Trieste, Dipartimento di Storia e Storia dell'Arte, 23-25 settembre 2004

    Directory of Open Access Journals (Sweden)

    Guido Abbattista (a cura di

    2005-01-01

    Full Text Available Guido Abbattista - Rolando Minuti, Premessa Marcel Dorigny, Yves Benot (1920-2005 Guido Abbattista, Africains en exposition (Italie XIXe siècle entre racialisme, spectacularité et humanitarisme Sophie Audidière, Nature humaine et diversité: la facticité selon Helvétius Yves Benot, Les Sauvages d’Amérique du nord: modèle ou épouvantail? Carminella Biondi, "De la littérature des nègres" de l’abbé Grégoire: un plaidoyer manqué? Andrew Curran, Imaginer l’Afrique au siècle des Lumières Thierry Hoquet, La nouveauté du Nouveau Monde du point de vue de l'histoire naturelle Girolamo Imbruglia, Un impero d'età moderna: la Compagnia di Gesù Renato G. Mazzolini, L’interpretazione simbolica della pigmentazione umana nell’antropologia fisica del primo Ottocento Rolando Minuti, Tolleranza e islam. Aspetti di un dibattito tra Seicento e Settecento Marco Platania, Formes de la liberté: images politiques des Indiens d’Amérique dans la deuxième moitié du XVIIIe siècle Emmanuelle Sibeud, "Comment peut-on etre noir ?" Le parcours d'un intellectuel haïtien a la fin du XIXe siècle Ann Thomson, L'Europe des lumieres et le monde musulman: une alterite ambiguë Larry Wolff, The Adriatic Origins of European Anthropology

  12. Paramarteilia canceri sp. n. (Cercozoa) in the European edible crab (Cancer pagurus) with a proposal for the revision of the order Paramyxida Chatton, 1911.

    Science.gov (United States)

    Feist, Stephen W; Hine, P Mike; Bateman, Kelly S; Stentiford, Grant D; Longshaw, Matt

    2009-06-01

    transferred to Paramarteilia. Further, Paramyxoides Larsson et Køie, 2005 is considered as a junior synonym of Paramyxa and its type and only species, Paramyxoides nephtys Larsson et Køie, 2005, is transferred to Paramyxa.

  13. L’antéposition de l’adjectif : quelles contreparties sémantiques ?

    Directory of Open Access Journals (Sweden)

    Henkel Daniel

    2016-01-01

    Full Text Available Il a souvent été remarqué que les adjectifs du français en fonction épithète peuvent soit être antéposés, soit postposés, à leur nom recteur (cf. Delbecque (1990, Gil et al. (2012, Radatz & Stammerjohann (1996, Scarano (2005. Cette mobilité de l’adjectif suscite des interrogations aussi bien d’un point de vue syntaxique que sémantique (cf. Waugh (1976, Forsgren (1978, Abeillé & Godard (1999. J. Goes (1999, notamment, s’est inspiré de Larsson (1994 et de Blinkenberg (1933 pour défendre et développer l’idée selon laquelle les adjectifs antéposés seraient « désémantisés », c’est-à-dire sémantiquement réduits (Blinkenberg, et de ce fait compatibles avec une plus grande variété de noms supports (Larsson. En nous aidant d’un corpus électronique de français écrit de 5 millions de mots, constitué de 50 œuvres du domaine public de 50 auteurs différents, et étiquetés par catégories grammaticales, nous avons cherché à tester la prédiction selon laquelle l’antéposition des adjectifs aurait pour corrélat une plus grande distribution lexicale des noms supports. À la lumière de nos recherches, il s’est avéré que, contre toute attente, la diversité lexicale des substantifs est moindre dans les séquences à épithète antéposée, et que certains substantifs présentent des affinités ou des résistances avec la qualification en antéposition ou en postposition.

  14. Wall-modeled large-eddy simulation of transonic airfoil buffet at high Reynolds number

    Science.gov (United States)

    Fukushima, Yuma; Kawai, Soshi

    2016-11-01

    In this study, we conduct the wall-modeled large-eddy simulation (LES) of transonic buffet phenomena over the OAT15A supercritical airfoil at high Reynolds number. The transonic airfoil buffet involves shock-turbulent boundary layer interactions and shock vibration associated with the flow separation downstream of the shock wave. The wall-modeled LES developed by Kawai and Larsson PoF (2012) is tuned on the K supercomputer for high-fidelity simulation. We first show the capability of the present wall-modeled LES on the transonic airfoil buffet phenomena and then investigate the detailed flow physics of unsteadiness of shock waves and separated boundary layer interaction phenomena. We also focus on the sustaining mechanism of the buffet phenomena, including the source of the pressure waves propagated from the trailing edge and the interactions between the shock wave and the generated sound waves. This work was supported in part by MEXT as a social and scientific priority issue to be tackled by using post-K computer. Computer resources of the K computer was provided by the RIKEN Advanced Institute for Computational Science (Project ID: hp150254).

  15. SWEDISH CRIME FICTION AS SOCIALLY INVOLVED LITERATURE

    Directory of Open Access Journals (Sweden)

    Monika Samsel-Chojnacka

    2011-01-01

    Full Text Available Swedish crime novel has been transforming for many years to become more socially involved. The ambition of many writers is not only to entertain the readers but also to participating in the social debate, criticizing the political and economical system, focusing on important issues such as violence against women, exploitation of working class by the privileged ruling class, the problems of a modern family and the situation of immigrants. Since the moment when in the mid 60’s two journalists Maj Sjöwall and Per Wahlöö decided to use popular literature to spread social matters many other Swedish writers have decided to follow their way. Some of them are journalists – like Liza Marklund, Börge Hellström and Anders Roslund or Stieg Larsson. Their novels as well as the ones written by Henning Mannkel on Kurt Wallander have become crucial evidence of changes of Swedish society in the past twenty years. Modern Swedish crime fiction illustrates the population in the model fashion that is the reason why it can become one of the interests of the sociology of literature.

  16. Hybrid Large-Eddy/Reynolds-Averaged Simulation of a Supersonic Cavity Using VULCAN

    Science.gov (United States)

    Quinlan, Jesse; McDaniel, James; Baurle, Robert A.

    2013-01-01

    Simulations of a supersonic recessed-cavity flow are performed using a hybrid large-eddy/Reynolds-averaged simulation approach utilizing an inflow turbulence recycling procedure and hybridized inviscid flux scheme. Calorically perfect air enters a three-dimensional domain at a free stream Mach number of 2.92. Simulations are performed to assess grid sensitivity of the solution, efficacy of the turbulence recycling, and the effect of the shock sensor used with the hybridized inviscid flux scheme. Analysis of the turbulent boundary layer upstream of the rearward-facing step for each case indicates excellent agreement with theoretical predictions. Mean velocity and pressure results are compared to Reynolds-averaged simulations and experimental data for each case and indicate good agreement on the finest grid. Simulations are repeated on a coarsened grid, and results indicate strong grid density sensitivity. Simulations are performed with and without inflow turbulence recycling on the coarse grid to isolate the effect of the recycling procedure, which is demonstrably critical to capturing the relevant shear layer dynamics. Shock sensor formulations of Ducros and Larsson are found to predict mean flow statistics equally well.

  17. Convergencia hacia la economía regional líder en México. Un análisis de cointegración en panel

    Directory of Open Access Journals (Sweden)

    Jesús Díaz Pedroza

    2009-01-01

    Full Text Available El objetivo de este artículo es ofrecer evidencia empírica sobre la convergencia del PIB per capita de los estados de la República Mexicana hacia el PIB del Distrito Federal, al que consideramos como la economía líder (Barro y Sala-i-Martin; 1991, 1992. Para ello, se aplican dos pruebas de raíces unitarias y ocho de cointegración en panel (Im, Pesaran y Shin, 1997; Levin-Lin, 1993, Pedrioni, 2001; Larsson, 2001. Estas pruebas resuelven el problema de las distorsiones por el uso de muestras pequeñas, propias de las series de tiempo. Las pruebas de raíces unitarias muestran que no hay evidencia de convergencia absoluta de 1970 a 2004 y para otros dos subperiodos. Sin embargo, las pruebas de cointegración arrojan evidencia en favor de la convergencia condicional para el mismo periodo. Las estimaciones de la velocidad de convergencia (Mark y Sul, 2003 indican que las regiones más ricas convergen más rápidamente que las pobres.

  18. One algorithm to rule them all? An evaluation and discussion of ten eye movement event-detection algorithms.

    Science.gov (United States)

    Andersson, Richard; Larsson, Linnea; Holmqvist, Kenneth; Stridh, Martin; Nyström, Marcus

    2016-05-18

    Almost all eye-movement researchers use algorithms to parse raw data and detect distinct types of eye movement events, such as fixations, saccades, and pursuit, and then base their results on these. Surprisingly, these algorithms are rarely evaluated. We evaluated the classifications of ten eye-movement event detection algorithms, on data from an SMI HiSpeed 1250 system, and compared them to manual ratings of two human experts. The evaluation focused on fixations, saccades, and post-saccadic oscillations. The evaluation used both event duration parameters, and sample-by-sample comparisons to rank the algorithms. The resulting event durations varied substantially as a function of what algorithm was used. This evaluation differed from previous evaluations by considering a relatively large set of algorithms, multiple events, and data from both static and dynamic stimuli. The main conclusion is that current detectors of only fixations and saccades work reasonably well for static stimuli, but barely better than chance for dynamic stimuli. Differing results across evaluation methods make it difficult to select one winner for fixation detection. For saccade detection, however, the algorithm by Larsson, Nyström and Stridh (IEEE Transaction on Biomedical Engineering, 60(9):2484-2493,2013) outperforms all algorithms in data from both static and dynamic stimuli. The data also show how improperly selected algorithms applied to dynamic data misestimate fixation and saccade properties.

  19. Simulation of a Wall-Bounded Flow using a Hybrid LES/RAS Approach with Turbulence Recycling

    Science.gov (United States)

    Quinlan, Jesse R.; Mcdaniel, James; Baurle, Robert A.

    2012-01-01

    Simulations of a supersonic recessed-cavity flow are performed using a hybrid large-eddy/ Reynolds-averaged simulation approach utilizing an inflow turbulence recycling procedure and hybridized inviscid flux scheme. Calorically perfect air enters the three-dimensional domain at a free stream Mach number of 2.92. Simulations are performed to assess grid sensitivity of the solution, efficacy of the turbulence recycling, and effect of the shock sensor used with the hybridized inviscid flux scheme. Analysis of the turbulent boundary layer upstream of the rearward-facing step for each case indicates excellent agreement with theoretical predictions. Mean velocity and pressure results are compared to Reynolds-averaged simulations and experimental data for each case, and these comparisons indicate good agreement on the finest grid. Simulations are repeated on a coarsened grid, and results indicate strong grid density sensitivity. The effect of turbulence recycling on the solution is illustrated by performing coarse grid simulations with and without inflow turbulence recycling. Two shock sensors, one of Ducros and one of Larsson, are assessed for use with the hybridized inviscid flux reconstruction scheme.

  20. The Lagerlunda collision and the introduction of color vision testing.

    Science.gov (United States)

    Mollon, J D; Cavonius, L R

    2012-01-01

    In histories of vision testing, the origins of occupational screening for color blindness are often traced to a fatal railroad accident that occurred in Sweden on the night of 14-15 November 1875. The scene of the accident was the estate of Baron Lagerfelt in Östergötland, but the critical events were played out at Linköping (the normal passing place for the northbound and southbound expresses) and at Bankeberg (a small station to which the passing place was reassigned at a few minutes' notice). First to arrive at Bankeberg, the northbound express slowed almost to a halt, but then inexplicably accelerated forwards towards the Lagerlunda estate, despite a sequence of signals from the stationmaster, Uno Björkelund, and a lineman, Oskar Johansson. Soon after the accident, the ophthalmologist Frithiof Holmgren suggested that the engineer of the northbound express, Andersson, or his oiler, Larsson, had been color blind. Neither survived to be tested. Using the records of the subsequent trial and other archival materials, we have re-examined the role of color blindness in the Lagerlunda incident and conclude that the accident cannot be attributed to color blindness alone. Yet the accident undoubtedly had a central role in the introduction of color vision testing by European and North American railroads. To persuade the railroad management to introduce universal screening of employees for color blindness, Holmgren used a dramatic coup de theatre and some unashamed subterfuge. Copyright © 2012 Elsevier Inc. All rights reserved.

  1. 《龙文身的女孩》第四部全球发行

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    9月25日书商瑞典推理小说家斯蒂格·拉松(Stieg Larsson)突然去世十一年后,其超级畅销书《千禧》三部曲经著名捉刀手全新演绎,第四部《蜘蛛网里的女孩》(The Girl in the Spider’s Web)于9月1日在美国和不包括中国在内的全球约四十个国家和地区同步上市。拉松的《千禧》三部曲由《龙文身的女孩》、《玩火的女孩》和《踢蜂巢的女孩》组成,描写了男中年调查记者米卡埃尔·布洛姆奎斯特和女青年电脑黑客莉丝贝

  2. Who will Change the Rule of the Publishing?%谁能改变出版的模式?

    Institute of Scientific and Technical Information of China (English)

    吕理哲

    2011-01-01

    @@ 2009年全世界有20几家包括台湾和内地的大小电脑公司,都加入了电子书阅读器的制造生产,起因于亚马逊网络书店(amazon.com)利用电子书阅读器Kindle开启了电子书的市场. 到了2010年底,亚马逊书店成功地销售了近千万台的Kindle,更卖出了上亿本的电子书,因此出现了第一位卖出100万eBook版权的作家--瑞典的Steig Larsson;也让美国的BoydMorrison自己把小说弄成电子书,自行挂上亚马逊Kindle Publishing Program 去卖eBook,他写的几个月都是排行榜的第一名,最后吸引了总共有44个国家的出版社和他签订了出版纸本小说的合同,创造了世界上第一位不需要出版社编辑,平步青云并戴上畅销作家桂冠的新典范.

  3. Science communication: Bridging the gap between theory and practise

    CERN Multimedia

    2001-01-01

    The 6th Public Communication of Science and Technology network conference will be held at CERN on 1-3 Febraury 2001. Scientists and communication professionals will analyse the state of the art of science communication and the new perception people have about science in the media from newspapers to the Web.   Will communication be able to bridge the gap between Science and Society? What is the impact of science communication on the public? How do novel means of communications change the perception of science for the general public? These and other interesting questions will be addressed at the 6th Public Communication of Science and Technology Meeting, to be held at CERN on 1-3 February 2001. More than 250 people from all over the world are expected to attend the conference which will be an important meeting place for communication professionals covering the social, political, technical and cultural aspects of science and technology communication. Georges Boixader after Gary Larsson. The conferenc...

  4. Spänningslitteratur för barn och vuxna: När målgrupper och genrer korsas i verkens paratexter

    Directory of Open Access Journals (Sweden)

    Kärrholm, Sara

    2016-12-01

    Full Text Available Many of the established Swedish crime writers write for both adults and young readers. These authors are successful in the two literary market segments that are dominating the contemporary Swedish book market: crime literature and children’s literature. Can certain developed trademarks in their authorship for adults be used in order to market books for other age groups and to what extent do the authors use this possibility? This article specifically addresses three authors writing for both young and adults: Anna Jansson, Kristina Ohlsson and Åsa Larsson. Their novels for a younger audience are analysed based on how they are packaged and marketed through paratexts such as covers, illustrations, and other texts, using Gérard Genette’s theory of paratexts and theories of genre and marketing. The analysis shows that these authors and their publishers use similar, but also different strategies to hold on to their former target group while also reaching out to new readers. The adult crime genre has an indirect influence over the market of mystery books for children, which is also seen in how different aspects of the crime market for adult crime fiction have become more important on the book market for children, involving agents, events and tourism.

  5. COLLOIDON BABY WITH OPHTHALMIC INVOLVEMENT

    Directory of Open Access Journals (Sweden)

    Shrinivas M

    2014-12-01

    Full Text Available Collodion baby is a rare, genetic heterogeneous skin disorder. It refers to a clinicentity used for newborns who are encased by a translucent, tight and parchment paper like skin sheets so called collodion membrane, on the entire body surface. 1 Collodion baby is a phenotype which broadly describes the above condition which includes a number of phenotypes. The two most common phenotypes are lamellar ichthyosis and non-bullous congenital erythroderma which account for 75% of cases and others like Sjögren-Larsson syndrome, Netherton syndrome, Gaucher disease etc account for 15% of the cases. 2 Lamellar ichthyosis which is more common, is an autosomal recessive condition caused by mutations in the transglutaminase-1 gene, defect on chromosome 14q11.Lid ectropion and ocular complications like exposure keratitis are seen commonly in colloidon babies. 3 15 day old male baby, first issue of a second degree consanguineously married couple, born at a gestation age of 36 weeks (normal vaginal delivery was referred to ophthalmic institute for management of ectropion. Child was diagnosed to have lamellar ichthyosis at the paediatric referral institute. At birth baby weighed 2500 grams, length 48 cm, head circumference of 34 cm.

  6. Genomic organization and expression of the human fatty aldehyde dehydrogenase gene (FALDH)

    Energy Technology Data Exchange (ETDEWEB)

    Rogers, G.R.; Markova, N.G.; Compton, J.G. [National Institutes of Health, Bethesda, MD (United States)] [and others

    1997-01-15

    Mutations in the fatty aldehyde dehydrogenase (FALDH) gene cause Sjoegren-Larsson syndrome (SLS) - a disease characterized by mental retardation, spasticity, and congenital ichthyosis. To facilitate mutation analysis in SLS and to study the pathogenesis of FALDH deficiency, we have determined the structural organization and characterized expression of the FALDH (proposed designation ALDH10) gene. The gene consists of 10 exons spanning about 30.5 kb. A TATA-less promoter is associated with the major transcription initiation site found to be 258 hp upstream of the ATG codon. The G4C-rich sequences surrounding the transcription initiation site encompassed regulatory elements that interacted with proteins in HeLa nuclear extracts and were able to promote transcription in vitro. FALDH is widely expressed as three transcripts of 2, 3.8, and 4.0 kb, which originate from multiple polyadenylation signals in the 3{prime} UTR. An alternatively spliced mRNA was detected that contains an extra exon and encodes an enzyme that is likely to have altered membrane-binding properties. The FALDH gene lies only 50-85 kb from ALDH3, an aldehyde dehydrogenase gene that has homologous sequence and intron/exon structure. 25 refs., 4 figs., 1 tab.

  7. Numerical Simulations of Separated Flows Using Wall-Modeled LES

    Science.gov (United States)

    Vane, Zachary; Ortega, Jason; Salari, Kambiz

    2014-11-01

    Calculations using an unstructured, wall-modeled large eddy simulation (WMLES) solver are performed for several high Reynolds number test cases of interest. While the equilibrium formulation of this wall-model (Bodart, Larsson & Moin, AIAA 2013-2724) has proven to be accurate for steady, attached boundary layers, its application to non-equilibrium or highly three-dimensional problems has yet to be fully explored. A series of turbulent flows that exhibit boundary layer separation due to the geometries involved in each test case are considered. First, spanwise-periodic simulations for the flow over periodic hills are performed at multiple Reynolds numbers. Next, calculations involving separation caused by three-dimensional bodies are used to generate more complex flow fields and to evaluate the accuracy of the WMLES in the separated wake region downstream. The performance of the WMLES is quantified through comparisons with existing numerical and experimental data sets. The effects of grid resolution and variations in several wall-model parameters are also investigated to determine their influence on the overall calculation.

  8. Primary Sjögren syndrome: report of a 10 years old girl with local edema and positivity of anti SS-A and anti SS-B autoantibodies

    Directory of Open Access Journals (Sweden)

    V. Gerloni

    2011-09-01

    Full Text Available Sjögren-Larsson syndrome (SLS is an autoimmune disease, uncommon in childhood. We report a case of SLS in a 10-year-old girl with a history of tumor, calor and rubor in the back of her toes almost every month, which resolved in 4-5 days without therapy. She did not complain of dry mouth or dry eyes. The laboratory fi ndings showed high infl ammation markers, rheumatoid factor 128 IU, Waaler-Rose 256 IU, anti nuclear antibody (ANA 1/640, SSA (anti Sjögren antigen A and SSB (anti Sjögren antigen B positive and hypergammaglobulinemia. The Schirmer’s test resulted to be pathologic, the ultrasonography images and biopsy of minor salivary glands revealed focal periductal lymphocytic infi ltrate and sialoduct ectasia class IV of juvenile Sjögren syndrome. The juvenile Sjögren syndrome is frequently under-diagnosed. Clinical manifestations in children might be different from the adult form, although laboratory fi ndings may be similar to those found in adults.

  9. Phytol in a pharma-medico-stance.

    Science.gov (United States)

    Islam, Md Torequl; de Alencar, Marcus Vinícius Oliveira Barros; da Conceição Machado, Katia; da Conceição Machado, Keylla; de Carvalho Melo-Cavalcante, Ana Amélia; de Sousa, Damiao Pergentino; de Freitas, Rivelilson Mendes

    2015-10-05

    This study aims to review phytol (PYT), through published articles, periodicals, magazines and patents, which were retrieved from the PM, SD, WS, SP; DII, WIPO, CIPO, USPTO and INPI databases. Among the 149 articles and 62 patents, 27.52% articles and 87.09% patients were found on the searched topic, PYT and its sources and synthesis and metabolism; then followed by 15.44% and 14.77% articles on PYT in cytotoxicity/cancer/mutagenicity/teratogenicity and PYT in neurological diseases, respectively. In the pharma-medico viewpoint, PYT and its derivatives have been evident to have antimicrobial, cytotoxic, antitumorous, antimutagenic, anti-teratogenic, antibiotic-chemotherapeutic, antidiabetic, lipid lowering, antispasmodic, anticonvulsant, antinociceptive, antioxidant, anti-inflammatory, anxiolytic, antidepressant, immunoadjuvancy, hair growth facilitator, hair fall defense and antidandruff activities. Otherwise, the important biometebolite of PYT is phytanic acid (PA). Evidence shows PA to have cytotoxic, anticancer, antidiabetic, lipid lowering and aniteratogenic activities. In addition, it may be considered as an important biomarker for some diseases such as Refsum's Disease (RD), Sjögren Larsson syndrome (SLS), rhizomelic chondrodysplasia punctata (RZCP), chronic polyneuropathy (CP), Zellweger's disease hyperpipecolic academia (ZDHA) and related diseases. Thus, phytol may be considered as a new drug candidate. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  10. Molecular Carbon in the Galaxy: Laboratory and Observational Studies

    Science.gov (United States)

    Saykally, Richard James

    2003-01-01

    In a collaboration with the Mats Larsson group from Stockholm, we carried out a new measurement of the rate of dissociative recombination of H(sup *, sub j), using a new pulsed supersonic beam source of rotationally cold H(sup *, sub j). This source was first designed and characterized in our lab by IR cavity ringdown spectroscopy, determining a rotationaYtranslationa1 temperature of 20-60K, depending on conditions. This new source was then taken to Stockholm for the recombination rate studies at the CRYRING storage ring. The recombination rate constant measured against temperature yields values consistent with the most recent calculations, whereas previous experimental measurements varied over a range of 10(exp 4) and were poor agreement with theory. This is a crucial achievement for understanding the ion chemistry of diffuse clouds. Moreover, this result in combination with recent observations implies a greatly enhanced (factor of 40) cosmic ray ionization rate in a diffuse cloud (zeta Persei) relative to previous studies. The implications of this are discussed in our recent Nature paper. An enhanced cosmic-ray flux towards zeta Persei inferred from a laboratory study of the H(sup *, sub j)-e(sup -) recombination rate.

  11. Food, Populations and Health — global Patterns and Challenges

    DEFF Research Database (Denmark)

    2016-01-01

    The present volume is based on presentations at a symposium at the Royal Danish Academy of Sciences and Letters in September 2014 with the title Food, Population and Health – global Patterns and Challenges. Food has played a fundamental role in the history of all societies over the World. Availab......The present volume is based on presentations at a symposium at the Royal Danish Academy of Sciences and Letters in September 2014 with the title Food, Population and Health – global Patterns and Challenges. Food has played a fundamental role in the history of all societies over the World...... spongiform encephalopathy and tuberculosis have been passed on from animals to humans through food. Larsson traces the Swedish outbreak of smallpox and dysentery in the 18th century and Revuelta-Eugercios discusses the promises of individual level data analysis on a mass basis as approach to socioeconomic...... have been as low as in nineteenth century Scandinavian low infant mortality regions. Gardarsdóttir demonstrates how increased breastfeeding in Iceland during 1850–1920 reduced infant mortality, but was still viewed with scepticism by many mothers. Based on the Dutch experience of famine 1944–45 Lumey...

  12. La spiritualité au miroir de l’ultramodernité

    Directory of Open Access Journals (Sweden)

    David Bisson

    2012-09-01

    Full Text Available Cet article analyse les mutations contemporaines du religieux à partir de deux angles d’approches novateurs. D’abord, l’inscription dans le contexte de l’ultramodernité qui se caractérise par une accélération de la modernité et qui nécessite de repenser le concept de sécularisation. Ensuite, la reprise du terme « spiritualité » pour tenter de comprendre les nouvelles modalités d’accès à la transcendance. Sur ce dernier point, nous proposerons une définition précise de la spiritualité avant de la confronter à certaines réalités sociologiques : « voie spirituelle » et « spiritualité holiste ». Au terme de l’article, nous interrogerons la notion de « spiritualité » au regard de ce que Yves Lambert nommait un « tournant axial », soit une reconfiguration générale du symbolique et du religieux.This article intends to highlight the topic of the transformation of the religious throughout the modern era using two different biases. First of all, by examining how the idea of religion takes root into the context of the “ultramodernity”, which is qualified by the acceleration of the modernity and makes it necessary to reconsider the concept of secularization. Then, we must also try to grasp a new way of understanding the term “spirituality” which would allow us to understand the new means of access to transcendence. Consequently, we will suggest a more precise definition of the spirituality before confronting it with certain sociological realities: “Spiritual Path” and “Holistic Spirituality”. To conclude, we willquestion the concept of “spirituality” according to what Yves Lambert named a “tournant axial”, in other terms: a general reconfiguration of the religious world.Este artículo analiza las mutaciones contemporáneas de lo religioso a partir de dos enfoques. El primero consiste en insertar estas transformaciones en el contexto de la « ultramodernidad » (o sea el de una

  13. Energy policy: challenges of a global vision; Politique energetique: les enjeux d'une vision globale

    Energy Technology Data Exchange (ETDEWEB)

    Destot, Michel [ed.] [Depute de l' Isere, Assemblee Nationale, Paris (France)

    2000-02-18

    This is the proceedings of the 2. parliamentary gathering on energy held on 14 October 1999. The document presents the talks by Mr Michel Destot (as special rapporteur of the Industry's budget in National Assembly) and Laurent Fabius, President of National Assembly, and Jean-Claude Gayssot, Minister of Equipment, Transport and Dwelling, at the opening session, three round tables, the colloquium synthesis and the closing session. The round tables addressed the following issues: - 1. International and long-term approach guided predominantly by energy demand; - 2. Energy solutions in the struggle against greenhouse effect; - 3. Challenges of opening the European energy market (internationalization and decentralization). At the first round table, Yves Martin, President of the technical section of General Council of Mines, structured his introductory report emphasizing the specific issues of three time horizons: the present, characterized by abundant energy offer; the horizon of 10 to 20 years, that of the energy suppliers which is orienting their investments; the horizon of more than half a century, corresponding to responses of far-reaching actions imposed by energy demand and which must be the object of governments' policies. Jean-Yves Le Deaut, deputy of Meurthe-et-Moselle discussed the risks of climate change, resources' exhaustion, nuclear power and the issue of developing the renewable energies. The problems raised by energy demand by the year 2050 to met the needs of an earth population of 9 billions were mentioned by Philippe Trepant, the president of French Union of oil industries. Energy problems from a globalization standpoint were discussed also by Benjamin Dessus, Director of Ecodev program of CNRS. Policy in the field of mastering greenhouse gas releases was mentioned in the talk by Michel Mousel, president of Inter-ministerial Mission for greenhouse effect. In the frame of 2. round table questions relating to energy management, renewable

  14. Micropolítica do trabalho vivo em ato, ergologia e educação popular: proposição de um dispositivo de formação de trabalhadores da saúde The micropolitics of living work in the act, ergology and popular education: a proposition of a device to train health workers

    Directory of Open Access Journals (Sweden)

    Suze Rosa Sant'Anna

    2011-01-01

    Full Text Available O presente artigo tem como objetivos discutir o trabalho em saúde e apresentar um dispositivo para a formação de trabalhadores sob a ótica do conceito ampliado de saúde, fundamentado em três principais referenciais teóricos: a démarche ergológica e seu dispositivo dinâmico a três polos de Yves Schwartz, a cartografia da micropolítica do trabalho vivo em ato de Emerson Elias Merhy e a educação popular em saúde, inspirada em Paulo Freire. Espera-se com este estudo contribuir para a reflexão e a construção de uma estratégia de formação para intensificar a inserção dos estudantes nos cenários de prática que enfatizem a construção compartilhada de conhecimentos e favoreçam especialmente a produção e efetivação de saberes e dos aspectos relacionais que compõem o núcleo tecnológico do cuidado em saúde.This article aims to discuss the work done in the health area and to present a tool to train workers under the light of the expanded concept of health, based on three main theoretical frameworks: Yves Schwartz' ergology demarche and its dynamic threepole tool; Emerson Elias Merhy's cartography of the micropolitics of living work in the act; and the popular health education, inspired in Paulo Freire. It is hoped that this study will contribute to a reflection on and to the construction of a training strategy to enhance the integration of students in practical activities that emphasize the shared construction of knowledge and, especially, encourage the production and realization of knowledge and relational aspects that make up the technological core in health care.

  15. Théories du théâtre autochtone au Canada depuis 1990. Refus de la posthistoire et réparation du corps social

    Directory of Open Access Journals (Sweden)

    François Paré

    2013-12-01

    Full Text Available Les compagnies théâtrales autochtones ont cherché à occuper tous les espaces de parole en produisant, au cours des années, non seulement un théâtre joué et très souvent publié, mais aussi un abondant discours d’accompagnement sur le sens à conférer aux œuvres produites sur scène et dans divers espaces publics. Ces textes de Qwo-Li Driskill, Candace Brunette, Daniel Heath Justice, Yves Sioui-Durand et Jo-Ann Episkenew, entre autres, nous permettent de saisir de l’intérieur le rôle privilégié assigné au théâtre et aux pratiques de la performance par toute une génération de chercheurs et d’activistes autochtones des trente dernières années. Nous en retenons que deux courants animent cette production théorique et méthodologique axée sur la décolonisation : le refus des esthétiques liées à la posthistoire (postmodernisme et postcolonialisme et le recours à un imaginaire et un lexique empruntés aux études contemporaines du traumatisme individuel et collectif. Indigenous theatre collectives have been active on all fronts in recent years, not only by staging and publishing a large number of plays written by Native writers, but also through the production and circulation of a significant number of theoretical texts on Indigenous theatre methodologies. Writings by Qwo-Li Driskill, Candace Brunette, Daniel Heath Justice, Yves Sioui-Durand and Jo-Ann Episkenew, among others, allow us to understand from within the role assigned to the theatre by a generation of Indigenous activists and scholars. The performance space is seen as a decolonizing agency, rejecting concepts related to both postmodernism and postcolonialism in favour of traditional healing processes rooted in contemporary studies on collective and personal trauma.

  16. Energy policy: challenges of a global vision; Politique energetique: les enjeux d'une vision globale

    Energy Technology Data Exchange (ETDEWEB)

    Destot, Michel [ed.] [Depute de l' Isere, Assemblee Nationale, Paris (France)

    2000-02-18

    This is the proceedings of the 2. parliamentary gathering on energy held on 14 October 1999. The document presents the talks by Mr Michel Destot (as special rapporteur of the Industry's budget in National Assembly) and Laurent Fabius, President of National Assembly, and Jean-Claude Gayssot, Minister of Equipment, Transport and Dwelling, at the opening session, three round tables, the colloquium synthesis and the closing session. The round tables addressed the following issues: - 1. International and long-term approach guided predominantly by energy demand; - 2. Energy solutions in the struggle against greenhouse effect; - 3. Challenges of opening the European energy market (internationalization and decentralization). At the first round table, Yves Martin, President of the technical section of General Council of Mines, structured his introductory report emphasizing the specific issues of three time horizons: the present, characterized by abundant energy offer; the horizon of 10 to 20 years, that of the energy suppliers which is orienting their investments; the horizon of more than half a century, corresponding to responses of far-reaching actions imposed by energy demand and which must be the object of governments' policies. Jean-Yves Le Deaut, deputy of Meurthe-et-Moselle discussed the risks of climate change, resources' exhaustion, nuclear power and the issue of developing the renewable energies. The problems raised by energy demand by the year 2050 to met the needs of an earth population of 9 billions were mentioned by Philippe Trepant, the president of French Union of oil industries. Energy problems from a globalization standpoint were discussed also by Benjamin Dessus, Director of Ecodev program of CNRS. Policy in the field of mastering greenhouse gas releases was mentioned in the talk by Michel Mousel, president of Inter-ministerial Mission for greenhouse effect. In the frame of 2. round table questions relating to energy management, renewable

  17. Transparency, citizen participation, organisation and roles. Report from the third RISCOM-II Workshop

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, Kjell [Karinta-Konsult, Taeby (Sweden); Paeivioe, Josefin [Swedish Nuclear Power Inspectorate, Stockholm (Sweden)

    2003-10-01

    This workshop was the final one in a series of three workshops within the RISCOM II project. It was an event where the RISCOM group of researchers disseminated the results to a wider circle of the nuclear waste management community in Europe with the focus on their own 'peers' in participating countries. However, the aim was not just to present RISCOM II results but also to see them in the context of adjacent projects. Especially, the workshop was set up in cooperation with the NEA Forum on Stakeholder Confidence (FSC) since this was seen as a good opportunity for exchange of experiences between the two activities. There was also participation by representatives from the EC COWAM Concerted Action and one presentation was devoted to this activity. There was thus an opportunity to discuss the three activities together. A draft of the RISCOM II Final Report had been made available for workshop participants before the meeting. The first part of the workshop entitled Transparency and citizen participation was moderated by Yves Le Bars, FSC chairman, and president of ANDRA. The second part dealt with Outcomes of the RISCOM Project and was moderated by Elizabeth Atherton from UK Nirex. Magnus Westerlind (SKI), the RISCOM-II coordinator, moderated the third part that dealt with Organisation and roles.

  18. Orientation Club

    CERN Multimedia

    Club d'orientation

    2014-01-01

    COURSE ORIENTATION Résultats de samedi 10 mai    C’est sur une carte entièrement réactualisée dans les bois de Versoix, que plus de 100 coureurs sont venus participer à la course d’orientation, type longue distance, préparée par des membres du club du CERN. Le terrain plutôt plat nécessitait une orientation à grande vitesse, ce qui a donné les podiums suivants :  Technique long avec 17 postes : 1er Jurg Niggli, O’Jura en 52:48, 2e Beat Muller, COLJ Lausanne-Jorat en 58:02, 3e Christophe Vuitton, CO CERN en 58:19 Technique moyen avec 13 postes : 1er Jean-Bernard Zosso, CO CERN, en 46:05 ; 2e Yves Rousselot, Balise 25 Besançon, en 55:11 ; 3e Laurent Merat, O'Jura, en 55:13 Technique court avec 13 postes : 1er Julien Vuitton, CO CERN en 40:59, 2e Marc Baumgartner, CO CERN en 43:18, 3e Yaelle Mathieu en 51:42 Su...

  19. Rezension: Vom Scheitern der Demokratie – Die Pfalz am Ende der Weimarer Republik

    Directory of Open Access Journals (Sweden)

    Yves V. Grossmann

    2011-11-01

    Full Text Available The recent study about the history of what is today the federal state of Rheinland-Pfalz (Rhineland- Palatinate: „Vom Scheitern der Demokratie – Die Pfalz am Ende der Weimarer Republik“ has recently been reviewed by Yves V. Grossmann. Beginning with the world economic crisis in October 1929 and ending with Hitlers rise to power in 1933, co-publisher Hannes Ziegler approaches the contemporary time in the Rhinland-Palatinate region, which was marked by political instability and economic disaster. The time of crisis during the Weimar years advantaged the political rise of the Nazis, allowing the NSDAP to become a mass-party in the Pfalz-region. This historical rise to power is approached via twelve different articles, each of them looking at the named topic from a different angle. The volume also explicitly deals with the time of French occupation, the economic-crisis and the political radicalisation. The media history and the press are also included. The political landscape, the church, the law system, and the branch of cultural life, which thrived regardless of the crisis, are also being adressed throughout the regional-historicalthemed volume. The review offers a short and comprehensive summary of the book's contents. The classification and evaluation of the volume furthermore arrive at a thoroughly positive conclusion.

  20. Infiltration into soils: Conceptual approaches and solutions

    Science.gov (United States)

    Assouline, Shmuel

    2013-04-01

    Infiltration is a key process in aspects of hydrology, agricultural and civil engineering, irrigation design, and soil and water conservation. It is complex, depending on soil and rainfall properties and initial and boundary conditions within the flow domain. During the last century, a great deal of effort has been invested to understand the physics of infiltration and to develop quantitative predictors of infiltration dynamics. Jean-Yves Parlange and Wilfried Brutsaert have made seminal contributions, especially in the area of infiltration theory and related analytical solutions to the flow equations. This review retraces the landmark discoveries and the evolution of the conceptual approaches and the mathematical solutions applied to the problem of infiltration into porous media, highlighting the pivotal contributions of Parlange and Brutsaert. A historical retrospective of physical models of infiltration is followed by the presentation of mathematical methods leading to analytical solutions of the flow equations. This review then addresses the time compression approximation developed to estimate infiltration at the transition between preponding and postponding conditions. Finally, the effects of special conditions, such as the presence of air and heterogeneity in soil properties, on infiltration are considered.

  1. Interview with Daan Frenkel, Boltzmann Medallist 2016 : Simulating soft matter through the lens of statistical mechanics.

    Science.gov (United States)

    Frenkel, Daan; Louët, Sabine

    2016-06-01

    Daan Frenkel has been awarded the most important prize in the field of statistical mechanics, the 2016 Boltzmann Medal, named after the Austrian physicist and philosopher Ludwig Boltzmann. The award recognises Frenkel's seminal contributions to the statistical-mechanical understanding of the kinetics, self-assembly and phase behaviour of soft matter. The honour recognises Frenkel's highly creative large-scale simulations of soft matter capable of explaining the self-assembly of complex macromolecular systems, colloidal and biomolecular systems. Frenkel is Professor of Theoretical Chemistry at the University of Cambridge, UK and has been Editor in Chief of EPJE between 2010 and 2014. The award will be given to both Frenkel and his French colleague Yves Pomeau, during the StatPhys Conference on 20th July 2016 in Lyon, France. In this interview with Sabine Louët, Frenkel gives his views on statistical physics, which has become more relevant than ever for interdisciplinary research. He also offers some pearls of wisdom for the next generation Statistical Mechanics experts.

  2. The Prediction of Bankruptcy Using Backpropagation Algorithm for “IO” Model Analysis

    Directory of Open Access Journals (Sweden)

    Ciprian Dragota

    2007-01-01

    Full Text Available The basic question which every bank it putswhen a client or a future client whishes to take a bank loanis: “The future debtor it’s capable to refund the loan atmaturity? (Installments plus the interest“. To answer atthis question the bank makes an assessment in which assetsand liabilities are analyze. There is also assessed the creditrating, the cash flow, the securities and, very important,bankrupt risk analysis.For the last one, to calculate bankrupt risk analysis,banks use some models (knows as “Z” score. Few of themare financials methods (like Altman, Canon & Holder,Yves Colonques etc. Nevertheless, these models are beendevelop for a specific situation and for a western economywhich is functional and very articulated. For our economy,we propose a new model that is been build with the specificeconomic dates and inputs, the model we called “IO”model.Without pretending to be able to penetrate over thecomplexity of the phenomenon, this study is trying to do apractical and experimental analysis of bankruptcy usingback propagation algorithm applied to the ”IO” model.

  3. Relevance as Social Matrix of Attention in Alfred Schutz

    Directory of Open Access Journals (Sweden)

    Enrico Campo

    2016-01-01

    Full Text Available Attention is a critical faculty in contemporary Western societies. What is surprising is the fact that attention has been mainly analyzed as an individual phenomenon. Scientific research that treats attention exclusively on the individual level simplifies an enormously complex situation. Instead, according to the idea defended in this essay, one cannot think of attention and perception without regard for cultural conventions and social norms. This article therefore proposes to investigate attention precisely in its social dimension. In particular, the specific objective is to highlight the contribution Alfred Schutz’s theory of systems of relevance can give to the understanding of the social mechanisms that regulate attention. In order to demonstrate the viability of the Schutzian proposal, here are discussed some recent perspectives that explore the mechanisms of the social regulation of attention. The article will briefly revisit these contributions that explicitly investigate intersubjective and collective attention, and will focus especially on the proposals of Eviatar Zerubavel and Yves Citton. Then is analyzed the role of attention in the theoretical edifice of Schutz, to focus on the relationship between attention and systems of relevance.

  4. Poetic Recuperations: The Ideology and Praxis of Nouveau Réalisme

    Directory of Open Access Journals (Sweden)

    Roberdeau, Wood

    2012-08-01

    Full Text Available Taking previously un-translated writings of critic Pierre Restany as a primary source, this article demonstrates how his vision for the Nouveau Réaliste movement of the 1950s and 1960s demands a detailed and theoretical (rather than historically contextual exploration of its attempt to reconcile visual art with the quotidian. Accordingly, Bürger's criticism of the historical and neo-avant-gardes is weighed against theories of aesthetics and politics from Adorno to Rancière. In addition, Heidegger's work on the art object, alongside Benjamin's interest in Hölderlin, serves to inform an analysis of Restany's investment in a concept of the 'poetry of the real'. Individual works by Niki de Saint-Phalle, Daniel Spoerri and Yves Klein are also investigated as exemplars of the Nouveau Réaliste ideology. My interest in Restany's life and work stems from recent art world concentrations on the banal or 'infra-ordinary' and its relation to similar concerns within sociology.

  5. Staff Members with more than 25 years service at CERN in 2000

    CERN Multimedia

    2000-01-01

    Allegrini Roberto SL Arimatea Claudio SL Baudic Yves SPL Becquet Christian SL Bergamaschi Angelo ST Bourquin Pierre EST Brand Jean-Paul ST Bresciani Pietro EST Brocard Robert EP Cameron Willie EST Carminati Daniel PS Chasseloup De Laubat Jacques ST Chouvelon Alain TIS Cittolin Sergio EP Cochet Evelyne ST Coly Patrick LHC David Eric EP De Jonge Luit Koert SL Delattre André LHC Detraz Claude Charles EP Dreesen Peter PS Dydak Friedrich EP Favini Pierre EST Ferioli Gianfranco SL Fiebiger Heinz PS Fontbonne Andrée HR Fournel Jacques EST Fournier Gérard AS Fromm Daniel EP Gagliardi Fabrizio IT Gaidon Michèle ST Galbraith Peter LHC Gavaggio Richard LHC Genand Roger SL Gendre Francis PS Geoffroy Michel ST Geretschlager Ingrid ETT Grabit Robert EP Grill Manfred ST Heinze Wolfgang PS Hoh Roger PS Hudry Jean SL Jenny Bernard EST Koutchouk Jean-Pierre SL Laffin Michel SL Laurent Jean-Michel LHC Le Gras Marc PS Legrand Patrick LHC Lerho Jean-Marie ST Lewis Ray ETT Liptow Ulr...

  6. CERN Relay Race: sporty and colourful

    CERN Multimedia

    Andy Butterworth, CERN Running Club

    2013-01-01

    On Thursday 23 May, the 43rd CERN Relay Race took place, with 108 teams on the starting line, the largest participation ever!       The DG was present at the start and said a few words to encourage the runners. At 12:15, the Solar Club and handbike racers, led by Jean-Yves Le Meur, were the first to set off. And as last year, the relay runners were accompanied by an enthusiastic group of Nordic walkers. The first team across the finish line was "Velo City", in a very fast time of 10'31". New this year was a prize category for the best fancy dress, which was won by Les Schtroumpfs from the BE Department. The challenge for the best represented department was won for the third year in a row by FP, but second and third were HR and IT, up from 6th and 9th places last year. To see all the pictures of the event, click here.

  7. Compte-rendu : Tim Weiner, 2007, Legacy of Ashes. The History of the CIA, Doubleday : New York, 702 pages.

    Directory of Open Access Journals (Sweden)

    Walther, Olivier

    2007-11-01

    Full Text Available « La géographie, ça sert d’abord à faire la guerre » affirmait le géographe Yves Lacoste en 1976. Il montrait alors de quelle manière la maîtrise de l’espace pouvait également servir à l’exercice du pouvoir et l’impossibilité de séparer radicalement la pensée académique de celle des états-majors. Il n’y a sans doute pas de meilleure illustration contemporaine de ce principe que le dernier ouvrage consacré à la CIA par Tim Weiner, journaliste au New York Times. Car Legacy of Ashes est assurément plus qu’une histoire de la Central Intelligence Agency ; il est également une leçon sur l’espace des guerres menées par l’Amérique depuis la Seconde Guerre mondiale. De sa création sous le président Truman en 1947 à sa remise en question au lendemain de guerre en Irak en 2003, l’ouvrage de Tim Weiner parcourt les épisodes qui ont principalement marqué la bataille de la CIA contre le communisme, puis contre le terrorisme, jusqu’à sa mise sous tutelle actuelle au profit du Pentagone.

  8. ``Quantum'' interference with bouncing drops

    Science.gov (United States)

    Bohr, Tomas; Andersen, Anders; Madsen, Jacob; Reichelt, Christian; Lautrup, Benny; Ellegaard, Clive; Levinsen, Mogens

    2013-11-01

    In a series of recent papers (most recently) Yves Couder and collaborators have explored the dynamics of walking drops on the surface of a vibrated bath of silicon oil and have demonstrated a close analogy to quantum phenomena. The bouncing drop together with the surface wave that it excites seems to be very similar to the pilot wave envisaged by de Broglie for quantum particles. In particular, have studied a double slit experiment with walking drops, where an interference pattern identical to the quantum version is found even though it is possible to follow the orbits of the drops and unambigously determine which slit it goes through, something which in quantum mechanics would be ruled out by the Heisenberg uncertainly relations. We have repeated the experiment and present a somewhat more complicated picture. Theoretically, we study a Schrödinger equation with a source term originating from a localised ``particle'' being simultaneously guided by the wave. We present simple solutions to such a field theory and discuss the fundamental difficulties met by such a theory in order to comply with quantum mechanics.

  9. Preface: Phonons 2007

    Science.gov (United States)

    Perrin, Bernard

    2007-06-01

    de Compétence NanoSciences Ile-de-France/Paris District Competence Center in Nanosciences). I want also to point out the strong support given by three institutions: CNRS (Centre National de la Recherche Scientifique), INSP (Institut des NanoSciences de Paris) and SFA (Socitété Française d'Acoustique). Finally, I would like to thank the members of the different committees who helped for the organization of this conference. I am particularly indebted to Bernard Bonello, Arnaud Devos, Jean-Yves Duquesne, Jean-Yves Prieur and Clément Rossignol for their invaluable help. I appreciated the kindness and efficiency of Armelle Guilloux ('Ellipse & Co'). I want also to express my thanks to close collaborators: Catherine Dematteis, Agnès Huynh and Emmanuel Péronne. During the conference, I appreciated the valuable assistance of Sandrine Guit, Béatrice Desoudin and of the student team. The edition of these proceedings could not have been possible without the tremendous amount of work performed by Jean-Yves Duquesne and the valuable help of Jean-Yves Prieur. I hope that the delegates of PHONONS 2007 enjoyed the program and will be willing to attend the 13th conference which will be chaired by Professor Chi Kuang Sun in Taiwan in 2010. Bernard Perrin, Chairman of PHONONS 2007 Institut des NanoSciences de Paris, Paris, November 2007 Copyright: CNRS Photo - Nicole TIGET. The PDF contains the lists of committee members, sponsors and participants.

  10. Cose debitrici. Credenze, atmosfere, arte

    Directory of Open Access Journals (Sweden)

    Filippo Fimiani

    2012-05-01

    Full Text Available What happens when painting emancipates itself from all physical mediums, the piece of art disappears from the exposition site and it becomes immaterial, indiscernible within its surrounding space? What type of esthetic experience and embodied understanding of art is possible under these programmed and produced conditions, maybe dissimulated, and finally enunciated and affirmed next to and in place of that which presents itself with the title of art masterpiece? What type of description, definition and interpretation is necessary? What type of phenomenology, pragmatic, rhetoric, and ontology is called upon? What type of percepts, of effects and affects, of appearance and apparatus, are put into play in this esthetic relation lacking an artistic object? When there is nothing to see and to touch, what living forms, what beliefs, what qualities are dealt with? Until this day, after more than 50 years, the “Exposition of Void” of Yves Klein doesn’t quit asking these and other questions on aesthetics and to the history of art.

  11. Historical aspects of Mexican psychiatry.

    Science.gov (United States)

    Bayardo, Sergio Javier Villaseñor

    2016-04-01

    Mexican psychiatry initiated since pre-Hispanic times. Historically, treatments were a mixture of magic, science and religion. Ancient Nahuas had their own medical concepts with a holistic view of medicine, considering men and cosmos as a whole. The first psychiatric hospital appeared in 1566 and a more modern psychiatric asylum emerged until 1910. International exchanges of theoretical approaches started in the National University with the visit of Pierre Janet. There were other important figures that influenced Mexican psychiatry, such as Erich Fromm, Henri Ey, Jean Garrabé and Yves Thoret. Regarding Mexican psychiatrists, some of the most important contributors to Mexican psychiatry were José Luis Patiño Rojas, Manuel Guevara Oropeza and Ramón de la Fuente Muñiz. This article includes excerpts from "Clinical Psychiatry", a book by Patiño Rojas where he tries to understand and describe the inner world experienced by patients with schizophrenia; also, the thesis conducted by Guevara Oropeza ("Psychoanalisis"), which is a critical comparison between the theories of Janet and Freud. Finally, we include "The study of consciousness: current status" by Ramón de la Fuente, which leads us through the initial investigations concerning consciousness, its evolution, and the contributions made by psychology, philosophy and neurobiology.

  12. The 2005 Nobel Prize in Chemistry and related information%2005年诺贝尔化学奖与相关信息试题

    Institute of Scientific and Technical Information of China (English)

    仇国苏

    2006-01-01

    瑞典皇家科学院2005年10月5日11点45分宣布,将2005年诺贝尔化学奖授予法国石油研究所的伊夫·肖万(Yves Chauvin)、美国加州理工学院的罗伯特·格拉布(Robert H.Grubbs)和美国麻省理工学院的理查德·施罗克(Richard R.Schrock)。诺贝尔奖委员会在授予这三位科学家诺贝尔化学奖的文告中称,他们是因在有机化学的烯烃复分解反应研究方面作出了贡献而获奖的。这一方法是研究碳原子之间的化学联系是如何建立和分解的,是一种产生新的有机物分子的关键方法。

  13. Trabectedin and its potential in the treatment of soft tissue sarcoma

    Directory of Open Access Journals (Sweden)

    Philippe A Cassier

    2008-03-01

    Full Text Available Philippe A Cassier1, Armelle Dufresne1, Jean-Yves Blay1,2,3, Jérôme Fayette2,31Unité de Jour d’Oncologie Médicale Multidisciplinaire, Hôpital Edouard Herriot, Lyon, France; 2Département d’Oncologie Médicale, Centre Léon Bérard, Lyon, France; 3Unité INSERM 590, Equipe Cytokine et Cancer, Centre Léon Bérard, Lyon, FranceAbstract: Trabectedin is a new marine-derived compound that binds the DNA minor groove and interacts with proteins of the DNA repair machinery. Phase I trials have established the standard regimen as 1500 µg/m² 24-hour continuous infusion repeated every 3 weeks. Several phase II trials have shown response in 5%–10% of unselected patients with soft tissue sarcoma failing prior chemotherapy and disease stabilisation in 30%–40%. Furthermore, prolonged disease control has been described in 15%–20% of patients. Toxicities are mainly haematological and hepatic with grade 3–4 neutropenia and thrombocytopenia observed in approximately 50% and 20% of patients respectively, and grade 3–4 elevation of liver enzymes observed in 35%–50% of patients treated with trabectedin. Current research focuses on the identification of predictive factors for patients with soft tissue sarcoma treated with trabectedin.Keywords: chemotherapy, sarcoma, drug development, DNA repair

  14. What's new @CERN ?

    CERN Multimedia

    CERN video productions

    2011-01-01

    Le 30 mars 2010 – une date désormais gravée dans le marbre – le jour où le LHC, le grand collisionneur de hadrons, soit le plus puissant accélérateur de particules au monde a commencé à fonctionner à des énergies inédites. Depuis, les collisions s’enchainent avec la promesse de découvertes. Dans cette édition de What’s new at CERN?, nous allons faire le bilan des performances de cette machine et parler de son mode d’exploitation qui va changer dans quelques jours. Les mots clés de cette émission ? Performances – expériences – ions - protons - avenir Tout cela en compagnie de Steve Myers, directeur du CERN pour les accélérateurs et la technologie, et de Yves Schutz, physicien de l’expérience ALICE.

  15. Staff members with 25 years' service at CERN in 2005

    CERN Multimedia

    2005-01-01

    The 74 staff members who have spent 25 years at CERN in 2005 were invited by the Director-General to a reception in their honour on 22 November. ADRIAN Gilbert / AB ALLIOD Marie-Noëlle / AB ANTOINET Gérard / SC AUBERT Marc / TS AUQUIER Christian / SC BAIRD Simon / AB BARRAS Suzanne / PH BAUD Richard / AT BELLONI Jean / SC BERTUOL Gilbert / SC BLANC Jean-Luc / AB BONVALLET Guy / SC BOSSUS Patrice / SC BROERE Johannes / AB BRU Yvon / TS BURDAIRON Alain / TS CANARD Philippe / AT CAVALLO Patrice / SC CHARRA Patrick / PH CHATAIGNEAU Marc / SC COLIN Gilles / SC DAHLEN Pierre / AB DE GROOT Johannes / PH DEDOBBELER Bernard / TS DELCAMBRE Jean Pierre / SC DELENCLOS Yves / TS DEROYER Patrick / SC DESBISSONS Christian / SC DRAPER Mick / AB DROUX Pascal / FI DUCASTEL Claude / TS DUMUR Alain / SC FOCKER Gerrit / AB FOFFANO Giuseppe / TS FORRAT Isabelle / IT FREI Marie-José / DSU FRESSARD Michel / TS GAGNIERE Daniel / TS GIUDICI Pierre-Ange / PH GOICOECHEA Bernard / TS GUEHO Alain / TS GUENEHEC François / SC JE...

  16. First Invenio Workshop: CERN’s digital library software ten years on

    CERN Multimedia

    Joannah Caborn Wengler

    2012-01-01

    To mark the release of Invenio 1.0, the first User Group Workshop was held last week, with more than 40 developers, system administrators and librarians from 14 different countries attending. The participants were able to catch up on developments in CERN’s digital library software and get a glimpse of where it's going next.   “This is the first time we’ve held such a big workshop,” explains Jean-Yves Le Meur, head of Digital Library Services. “There was a lot of demand for an event like this, and bringing out version 1.0 of Invenio was an obvious time to do it.” Ask him what’s new in version 1.0 and he opens his eyes wide. “There’s so much, it’s hard to summarise. One key improvement is that the code and the database are stable, well tested and optimised, which makes the software more efficient.” The participants, on the other hand, highlight new features coming up in Invenio...

  17. A Tragédia da Cultura na Era da Técnica: Georg Simmel

    Directory of Open Access Journals (Sweden)

    Francisco Rüdiger

    2008-12-01

    Full Text Available Georg Simmel, embora pouco conhecido entre nós, conta-se entre os primeiros críticos ocidentais a pensar o futuro da cultura na era da técnica. Destoando dos juízos correntes em seu tempo (1900, o pensador não viu nesse processo um estágio superior da marcha do progresso, relacionando-o antes com a crise da cultura para a qual havia nos alertado Nietzsche. As considerações seguintes pretendem dar conta da maneira como sua reflexão sobre a tragédia da cultura que tem lugar em nosso tempo comporta um exame do sentido da técnica que pode nos ajudar a pensar o problema das novas tecnologias de comunicação, após ter se tornado um motivo recorrente nos escritos de vários pensadores da técnica de nosso século, de Oswald Spengler e Heidegger a Jacques Ellul, Yves Barel, Arthur Kroker e Eduardo Subirats.

  18. Imagem, Informação e Tecnologia: vídeo digital como objeto de estudo para Ciência da InformaçãoImagen, Información y Tecnología: video digital como objecto de estudio para la Ciencia de la Información

    Directory of Open Access Journals (Sweden)

    Helen Beatriz Frota Rozados

    2012-01-01

    Full Text Available Introdução: Aborda conceitos a respeito de tecnologias da imagem, no contexto da Ciência da Informação. Delimita o estudo do vídeo digital enquanto imagem, tecnologia e informação. Objetivo: Identifica as relações do vídeo digital com o conceito de informação estética. Metodologia: Pesquisa bibliográfica. Resultados: Os principais autores da fundamentação teórica são Abraham Moles, Arlindo Machado, Philippe Dubois, Lev Manovich, Lucia Santaella, Yves-François Le Coadic, Silvia Martin e Vilém Flusser os quais abordam temas sobre máquinas de imagens (fotografia, cinema, televisão, vídeo e computador, Ciência da Informação e vídeo digital. Conclusões: O vídeo digital desaparece em sua especificidade para ressurgir como uma presença totalitária junto ao computador e a outros dispositivos tecnológicos.

  19. Crítica de Libros.

    Directory of Open Access Journals (Sweden)

    Juan Medrano

    2010-01-01

    Full Text Available René Descartes, La búsqueda de la verdad mediante la luz natural, KRK, 2009, 104 pp. Mauricio Jalón VV. AA., El rival de Prometeo. Vidas de autómatas ilustres, Impedimenta, 2009, 396 pp.Óscar Rubín. Roland Barthes, Diario de duelo, Paidós, 2009, 272 pp. Mauricio Jalón Georg es Didi-Huberman, Survivance des lucioles, Minuit, 2009, 144 pp.Andrea Rubín Yves Bonnefoy, Relatos en sueños, Cuatro, 2009, 174 pp. Vicente Pizarro Natalia Ginzburg , Ensayos, Lumen, 2009, 448 pp. Mauricio Jalón Boris Savinkov, El caballo amarillo. Diario de un terrorista ruso, Impedimenta, 2009, 184 pp. Esteban Calvo Michel Salazar, Concha Peralta, Francisco Javier Pastor, Tratado de psicofarmacología. Bases y aplicación clínica. (2ª Ed.. Editorial Médica Panamericana, 2009, 948 pp. Talía Rincón Shorter E, Healy D., Shock Therapy. A History of Electroconvulsive treatment in mental illness. New Brunswick: Rutgers, 2007. Juan Medrano

  20. Le CERN, chance ou risque pour Genève

    CERN Document Server

    Maiani, Luciano; Wenninger, Horst; CERN. Geneva

    1998-01-01

    Le CERN, Chance ou Risque pour Gen?ve? D?bat public contradictoire organis? avec le soutien de la Tribune de Gen?ve Lieu: Salle II, CICG,15 Rue de Varemb?. Date: Lundi 19 octobre 1998, 20h00 D?roulement de la soir?e: 1. Ouverture M. Ren? KÏchlin, Pr?sident du Grand Conseil M. Luciano Maiani, Directeur g?n?ral d?sign? du CERN 2. Introduction: Un regard critique sur le CERN (? d?signer) Le projet LHC (Manfred Buhler Broglin CERN) 3. D?bat th?matique men? par le mod?rateur (Marco Cattaneo, r?dacteur en chef de la Tribune de Gen?ve) entre trois representants de lÕopinion publique (Ren? Longet, d?put? socialiste; Yves de Pr?ville, physicien; Jacques Mirenowicz, chercheur) et trois repr?sentants du Cern (Horst Wenninger, Directeur de la Recherche/Technique, CERN; Manfred Buhler Broglin, Administra-teur du projet LHC, CERN; Maurice Bourquin, Professeur de Physique ? l'Universit? de Gen?ve et D?l?gu? de la Suisse au Conseil du CERN). Les th?mes abord?s seront: Ð A quoi sert le CERN? Ð Quel est lÕimpact ?conomiqu...

  1. «Quel desiderio ardentissimo di tradurre» Lo Streben della traduzione tra Leopardi e Bonnefoy

    Directory of Open Access Journals (Sweden)

    Novella Primo

    2013-05-01

    Full Text Available Molti sono gli investimenti che entrano in gioco nella traduzione letteraria.Tenendo presente alcuni importanti studi traduttologici sull’argomento, lo studio trae le mosse da Giacomo Leopardi che si sofferma a livello teorico e pratico sulla traduzione secondo una prospettiva ‘desiderante’: nello Zibaldone, nei paratesti delle sue opere e soprattutto nei giovanili Scherzi epigrammatici.Da Leopardi traduttore si proverà poi a passare a Leopardi tradotto.Tra i tanti esempi possibili, quello di Yves Bonnefoy è particolarmente significativo in quanto il letterato francese inscrive la traduzione da Leopardi entro una precisa dinamica del Desiderio («per quanto insufficiente sia la traduzione, […] essa ha dato forma a un desiderio, rivelato un affetto» che diviene la chiave, nei testi critici, per la comprensione della stessa poesia del Recanatese come avviene nella sua singolare traduzione-interpretazione del Canto notturno in cui la luna, vicina al pastore, accetta di «boir de son désir, de son espérance», accompagnandolo «riante».Bonnefoy riflette, anche a proposito di altri autori tradotti come Shakespeare, sui «fantasmes» del testo che il poeta-traduttore, animato da un forte «désir conceptuel», deve sapere individuare affinché possa leggere l’opera da tradurre in rapporto al senso enigmatico della poesia e della lettura poetica, al senso cioè del suo Desiderio.

  2. Increased Automation in Stereo Camera Calibration Techniques

    Directory of Open Access Journals (Sweden)

    Brandi House

    2006-08-01

    Full Text Available Robotic vision has become a very popular field in recent years due to the numerous promising applications it may enhance. However, errors within the cameras and in their perception of their environment can cause applications in robotics to fail. To help correct these internal and external imperfections, stereo camera calibrations are performed. There are currently many accurate methods of camera calibration available; however, most or all of them are time consuming and labor intensive. This research seeks to automate the most labor intensive aspects of a popular calibration technique developed by Jean-Yves Bouguet. His process requires manual selection of the extreme corners of a checkerboard pattern. The modified process uses embedded LEDs in the checkerboard pattern to act as active fiducials. Images are captured of the checkerboard with the LEDs on and off in rapid succession. The difference of the two images automatically highlights the location of the four extreme corners, and these corner locations take the place of the manual selections. With this modification to the calibration routine, upwards of eighty mouse clicks are eliminated per stereo calibration. Preliminary test results indicate that accuracy is not substantially affected by the modified procedure. Improved automation to camera calibration procedures may finally penetrate the barriers to the use of calibration in practice.

  3. Una mirada a las tensiones y fluctuaciones paradigmáticas de las prácticas pedagógicas

    Directory of Open Access Journals (Sweden)

    Gonzalo Miguel Castillo

    2014-06-01

    Full Text Available A continuación se presenta una aproximación a la actualización de las prácticas áulicas de la educación universitaria. La lectura del fenómeno fue realizada a partir de los conceptos de Revolución Científica propuesto por Thomas Kuhn, Poder y Tecnologías del Yo propuestas por Michel Foucault, Obstáculos Epistemológicos propuesto por Gaston Bachelard y Transposición Didáctica de Yves Chavallard. Tomando como eje triangulador la sistemática de la práctica docente propuesta por Violeta Guyot. Paralelamente, el objetivo general consiste en articular las nociones previamente descriptas con la percepción del autor respecto a sus prácticas como alumno adscripto universitario y sus primeras experiencias en la docencia formal. Las diferentes cátedras que son colocadas a modo de ejemplo experiencial presentan un considerable nivel de heterogeneidad permitiendo sostener la tesis del presente ensayo.

  4. Increased Automation in Stereo Camera Calibration Techniques

    Directory of Open Access Journals (Sweden)

    Brandi House

    2006-08-01

    Full Text Available Robotic vision has become a very popular field in recent years due to the numerous promising applications it may enhance. However, errors within the cameras and in their perception of their environment can cause applications in robotics to fail. To help correct these internal and external imperfections, stereo camera calibrations are performed. There are currently many accurate methods of camera calibration available; however, most or all of them are time consuming and labor intensive. This research seeks to automate the most labor intensive aspects of a popular calibration technique developed by Jean-Yves Bouguet. His process requires manual selection of the extreme corners of a checkerboard pattern. The modified process uses embedded LEDs in the checkerboard pattern to act as active fiducials. Images are captured of the checkerboard with the LEDs on and off in rapid succession. The difference of the two images automatically highlights the location of the four extreme corners, and these corner locations take the place of the manual selections. With this modification to the calibration routine, upwards of eighty mouse clicks are eliminated per stereo calibration. Preliminary test results indicate that accuracy is not substantially affected by the modified procedure. Improved automation to camera calibration procedures may finally penetrate the barriers to the use of calibration in practice.

  5. Smart rules: six ways to get people to solve problems without you.

    Science.gov (United States)

    Morieux, Yves

    2011-09-01

    As the world has become more complex, companies have steadily increased their performance requirements: Now they strive to offer low prices and high quality; to customize products for local markets and standardize them for greater returns; to innovate and be efficient. The typical corporate response to such conflicting goals complicates things further: Firms restructure and try to align their organizations with extra coordinating functions, processes, and incentives. This approach does more harm than good. Managers' time gets sucked up by reports and meetings, leaving little time to work with employees. But there is a better way, says BCG senior partner Yves Morieux: Instead of strangling employees with new rules and procedures, create an environment in which they're compelled to work with one another to develop solutions to complex challenges. Managers can create this environment by applying six "smart rules": (1) improve understanding of what coworkers do and the real constraints they face, (2) determine which people are the firm's natural integrators and strengthen their roles, (3) expand the amount of power available to everyone, (4) increase the need for reciprocity in the system, (5) make employees feel the "shadow of the future," and (6) hold uncooperative people accountable. By tapping employees' ingenuity through the use of smart rules, firms can manage complexity quickly and creatively-and streamline their organizations.

  6. Library science talks

    CERN Document Server

    Le Meur, Jean-Yves; Vigen, Jens; CERN. Geneva

    1997-01-01

    The new interface to the CERN library data base by Jean-Yves Le Meur / CERN-AS I will give a short (hands on) demonstration of the new interface to the whole library database. Emphasis will be given to the new feature allowing any user to build his personal virtual library. A user oriented interface to physics preprint servers by Carlos Loureno / CERN-PPE I will give a (hands-on) presentation of a first version of a tailor made WEB based interface to the preprints kept in the CERN or Los Alamos servers. This interface has already been successfully implemented for the field of high energy heavy ion physics, and can easily be expanded or adapted to other research fields of interest to the HEP community. For the already published papers, a direct link to the published e-journal version is provided (if available). Status of the digital library at CERN by Jens Vigen / CERN-AS I will review the present situation concerning the availability of the electronic versions of scientific publications at CERN and the el...

  7. Orienteering club

    CERN Multimedia

    Club d'orientation

    2013-01-01

    Course d'orientation Vers les dernières courses de printemps Une centaine de coureurs se sont déplacés sur le site de la Roche Fendue prés de Morez pour gouter à un des 5 parcours proposés par le club du O’Jura. Le terrain était gras mais que peut-on trouver d’autre avec cette météo! Les vainqueurs de chaque circuit sont : Alina Niggli (O’Jura) facile court, Natalja Niggli (O’Jura) facile moyen, Victor Kuznetsov (COLJ) technique court, Yves Rousselot (Balise 25) technique moyen et pour finir François Gonon (O’Jura) avec une victoire haut la main sur le technique long. Il ne reste plus que deux épreuves pour la coupe genevoise de printemps : à savoir samedi 8 juin, course de type longue distance organisée par le club de Lausanne Jorat (COLJ) dans le bois de Seyte sur Mutrux/Concise, inscription de 12h &...

  8. Investigation of airways using MDCT for visual and quantitative assessment in COPD patients

    Directory of Open Access Journals (Sweden)

    Pierre-Yves Brillet

    2008-03-01

    Full Text Available Pierre-Yves Brillet1, Catalin I Fetita2, Amaury Saragaglia2, Anne-Laure Brun3, Catherine Beigelman-Aubry3, Françoise Prêteux2, Philippe A Grenier31Department of Radiology, Avicenne Hospital, Assistance Publique–Hôpitaux de Paris, Université Léonard de Vinci–Paris Nord, EA 2361, Bobigny, France; 2ARTEMIS Department, Institut National des Télécommunications, Université Paris V, Evry, France; 3Department of Radiology, Pitié-Salpêtrière Hospital, Assistance Publique–Hôpitaux de Paris, Université Pierre et Marie Curie, Paris, FranceAbstract: Multidetector computed tomography (MDCT acquisition during a single breath hold using thin collimation provides high resolution volumetric data set permitting multiplanar and three dimensional reconstruction of the proximal airways. In chronic obstructive pulmonary disease (COPD patients, this technique provides an accurate assessment of bronchial wall thickening, tracheobronchial deformation, outpouchings reflecting dilatation of the submucous glands, tracheobronchomalacia, and expiratory air trapping. New software developed to segment adequately the lumen and walls of the airways on MDCT scans allows quantitative assessment of the airway dimensions which has shown to be reliable in clinical practice. This technique can become important in longitudinal studies of the pathogenesis of COPD, and in the assessment of therapeutic interventions.Keywords: COPD – tracheobronchial tree, multidetector CT – airway remodeling, tracheobronchomalacia

  9. O substrato mítico em A Paixão Segundo G.H, de Clarice Lispector

    Directory of Open Access Journals (Sweden)

    Mariângela Alonso

    2016-01-01

    Full Text Available A crítica tem apontado a narrativa A paixão segundo G.H. como representativa da síntese dos procedimentos artísticos de Clarice Lispector e o ápice de sua expressão literária. O procedimento da autora nesta obra apresenta uma ruptura com a forma tradicional do romance, na medida em que mescla traços característicos da prosa com elementos próprios da poesia, para relatar, em primeira pessoa, a viagem mítica da personagem G.H. em torno do espaço labiríntico de seu apartamento. Este artigo apresenta uma análise do substrato mítico presente em A paixão segundo G.H., fundamentada na teoria da narrativa poética formulada por Jean-Yves Tadié e Ralph Freedman. Palavras-chave: narrativa poética; Clarice Lispector; A paixão segundo G.H.; mito.

  10. Evolution of photography in maxillofacial surgery: from analog to 3D photography – an overview

    Directory of Open Access Journals (Sweden)

    Heidrun Schaaf

    2009-09-01

    Full Text Available Heidrun Schaaf, Christoph Yves Malik, Hans-Peter Howaldt, Philipp StreckbeinDepartment of Maxillo-Facial Surgery, University Hospital Giessen and Marburg GmbH, Giessen, GermanyAbstract: In maxillofacial surgery, digital photographic documentation plays a crucial role in clinical routine. This paper gives an overview of the evolution from analog to digital in photography and highlights the integration of digital photography into daily medical routine. The digital workflow is described and we show that image quality is improved by systematic use of photographic equipment and post-processing of digital photographs. One of the advantages of digital photography is the possibility of immediate reappraisal of the photographs for alignment, brightness, positioning, and other photographic settings, which aids in avoiding errors and allows the instant repetition of photographs if necessary. Options for avoiding common mistakes in clinical photography are also described and recommendations made for post-processing of pictures, data storage, and data management systems. The new field of 3D digital photography is described in the context of cranial measurements.Keywords: digital, photography, documentation, dental, 3D imaging

  11. Orienteering club

    CERN Multimedia

    Club d'orientation

    2013-01-01

    Courses d’orientation Samedi 20 avril, les organisateurs du Club de CO du CERN ont accueilli au Mont Mourex 70 participants qui n’ont pas hésité à venir malgré la forte bise. Berni Wehrle du CO CERN s’est octroyé la première place en 1:04:49 sur le parcours technique long devant Pyry Kettunen du Saynso Juankoski en 1:06:52, la 3e place revenant à Bruno Barge, CO CERN, à 7 secondes. Les autres parcours ont été remportés par : Technique moyen : 1er Jacques Moisset, Chamonix (47:44), 2e Yves Rousselot, Balise 25 Besançon (57:16), 3e Jean-Bernard Zosso, CO CERN (59:28). Technique court : 1er Victor Kuznetsov, COLJ (51:53), 2e Pierrick Collet, CO CERN (1:12:52), 3e Dominique Balay, CO CERN (1:16:04). Pour les parcours facile moyen et facile court, Ralf Nardini et Léa Nicolas, tous deux du CO CERN, terminaient respectivement premier. Voi...

  12. Talk | Physical preparation before a sports competition | 16 April

    CERN Multimedia

    2013-01-01

    In the run-up to the annual CERN Relay Race and as part of the Move! Eat better campaign, the Medical Service is organising a talk on physical preparation before a sports competition or before the start of a sporting season.     Come along to the Council Chamber on 16 April at 5:00 p.m. to discover the secrets of good physical preparation. You'll get plenty of tips, techniques and exercises, and find out how your whole sporting experience can be enhanced by good physical preparation.  This advice will be especially useful to help you prepare for the CERN Relay Race, whether you’re a casual jogger or a hardened road-racer. The talk will be moderated (in French) by: Rachel Bray, President of the CERN Fitness Club; Olivier Baldacchino, professional running coach and trainer of the CERN Running Club, who will give tips on how to prepare for races, in particular the CERN Relay Race; and Jean-Yves Le Meur, a member of the French national disa...

  13. L’ergonome et l’agent: quand la perspective anthropologique s’invite = O ergonomista e o agente: quando a perspectiva antropológica se convida

    Directory of Open Access Journals (Sweden)

    Castejon, Christine

    2014-01-01

    Full Text Available A partir de uma breve troca verbal que foi tomada como exemplo, a autora explicita como entende o conceito corpo-si elaborado pelo filósofo Yves Schwartz durante o processo que o conduziu de uma pesquisa sobre a experiência a uma antropologia da atividade. Isto fez surgir um questionamento sobre o lugar da linguagem, que a autora julga insuficiente nesta construção. De fato, o filósofo fala frequentemente dos limites da linguagem, mas tem tendência a deixar para a especialidade linguística um discurso mais completo ou mais informado sobre a linguagem. Com efeito, linguistas propagam a abordagem ergológica propondo teorias da atividade da linguagem. A autora propõe abrir uma nova perspectiva. Apoiando-se na obra de Henri Meschonnic, pensador francês da linguagem (igualmente poeta e tradutor, ela propõe avaliar o que faz a linguagem ao corpo-si e pensar na recíproca corpo-si e linguagem

  14. CDS Agenda and Webcast goes European

    CERN Multimedia

    2002-01-01

    The InDiCo team at CERN. From left to right: Jean-Yves Le Meur, Eric Simon, Thomas Baron, Héctor Sánchez. Imagine there is a conference at CERN you really want to attend, but for some reason you happen to miss it. Don't despair! Help is at hand in the shape of the CERN Document Server Agenda and Webcast Services. This tool can provide you with a wealth of material relating to the conference: transparencies, the conference agenda, even the video! And now, as part of the European Commission's Integrated Digital Conferencing (InDiCo) project, it is about to get even better. Within its Information Society Technologies Programme (IST), the EC has already allocated 1.8 MCHF over two years to develop a service platform for the production, archiving, searching and filtering of multimedia content from conferences and seminars. InDiCo is a project involving CERN, SISSA (International School for Advanced Studies, Trieste), the University of Udine, TNO (Netherlands Organisation for Applied Scientific Research) and th...

  15. Handbook of metaheuristics

    CERN Document Server

    Potvin, Jean-Yves

    2010-01-01

    “… an excellent book if you want to learn about a number of individual metaheuristics." (U. Aickelin, Journal of the Operational Research Society, Issue 56, 2005, on the First Edition) The first edition of the Handbook of Metaheuristics was published in 2003 under the editorship of Fred Glover and Gary A. Kochenberger. Given the numerous developments observed in the field of metaheuristics in recent years, it appeared that the time was ripe for a second edition of the Handbook. When Glover and Kochenberger were unable to prepare this second edition, they suggested that Michel Gendreau and Jean-Yves Potvin should take over the editorship, and so this important new edition is now available. Through its 21 chapters, this second edition is designed to provide a broad coverage of the concepts, implementations and applications in this important field of optimization. Original contributors either revised or updated their work, or provided entirely new chapters. The Handbook now includes updated chapters on the b...

  16. European National Society Cardiovascular Journals: Background, rationale and mission statement of the 'Editors' Club' (Task Force of the European Society of Cardiology).

    Science.gov (United States)

    Alfonso, F; Ambrosio, G; Pinto, F J; van der Wall, E E

    2008-06-01

    Anesti Kondili MD, Djamaleddine Nibouche MD, Karlen Adamyan MD, Kurt Huber MD, Hugo Ector MD, Izet Masic MD, Rumiana Tarnovska MD, Mario Ivanusa MD, Vladimír Stane k MD, Jørgen Videbaek MD, Mohamed Hamed MD, Alexandras Laucevicius MD, Pirjo Mustonen MD, Jean-Yves Artigou MD, Ariel Cohen MD, Mamanti Rogava MD, Michael Böhm MD, Eckart Fleck MD, Gerd Heusch MD, Rainer Klawki MD, Panos Vardas MD, Christodoulos Stefanadis MD, József Tenczer MD, Massimo Chiariello MD, Aleksandras Laucevicius MD, Joseph Elias MD, Halima Benjelloun MD, Olaf Rødevand MD, Piotr Kul/akowski MD, Edvard Apetrei MD, Victor A. Lusov MD, Rafael G. Oganov MD, Velibor Obradovic MD, Gabriel Kamensky MD, Miran F. Kenda MD, Christer Höglund MD, Thomas F. Lüscher MD, René Lerch MD, Moufid Jokhadar MD, Habib Haouala MD, Vedat Sansoy MD, Valentin Shumakov MD, Adam Timmis MD. (European National Society Cardiovascular Journals Editors, see Appendix for complete affiliations).

  17. Cistatina C e taxa de filtração glomerular em cirurgia cardíaca com circulação extracorpórea Cystatin C and glomerular filtration rate in the cardiac surgery with cardiopulmonary bypass

    Directory of Open Access Journals (Sweden)

    Marcello Laneza Felicio

    2009-09-01

    Full Text Available OBJETIVO: Avaliar a cistatina C como marcador de função renal em pacientes submetidos à cirurgia de cardíaca com circulação extracorpórea, comparando com a dosagem sérica de creatinina. MÉTODOS: Foram analisados 50 pacientes consecutivos submetidos à cirurgia de revascularização do miocárdio. A função renal foi avaliada com a dosagem sérica de cistatina C e de creatinina no pré-operatório, no primeiro e no quinto dia de pós-operatório. Foram utilizadas as fórmulas de Cockcroft-Gault (CG e Modification of Diet in Renal Disease (MDRD para calcular a taxa de filtração glomerular estimada (TFG através da creatinina, e a fórmula de Larsson para a TFG estimada através da cistatina C (TFG-Cis. RESULTADOS: A creatinina e o TFG através das fórmulas de CG e MDRD não mostraram diferença significativa nos momentos estudados. Após a agressão renal pela cirurgia, houve um aumento da cistatina C no 1º e 5º pós-operatório, sendo que no 5º pós-operatório com diferença estatisticamente significativa (P OBJECTIVE: The aim of this study was to compare cystatin C versus creatinine as a marker for acute kidney injury in patients submitted to cardiac surgery with cardiopulmonary bypass. METHODS: Fifty consecutive patients submitted to coronary artery bypass grafting were studied. Renal function was evaluated by serum cystatin C and creatinine. Blood samples were obtained from each patient at three time points: before operation, and on the first and fifth postoperative days. Glomerular filtration rate (GFR was calculated by Cockcroft-Gault (CG, Modification of Diet in Renal Disease (MDRD, and Larsson (Cys-GFR formulas. RESULTS: Creatinine and GFR by CG and MDRD formulas did not show statistical difference between study times. After renal injury from surgery, there was an increase in cystatin C on the 1st and 5th day after surgery, being significantly different on the 5th postoperative (P<0.01. The GFR by Larson formula was higher

  18. Cystatin C, kidney function, and cardiovascular risk factors in primary hypertension Cistatina C, função renal e fatores de risco cardiovascular na hipertensão primária

    Directory of Open Access Journals (Sweden)

    João Victor Salgado

    2013-02-01

    Full Text Available OBJECTIVE: To investigate the clinical usefulness of serum cystatin C (Scys and cystatin C-based equations for the screening of chronic kidney disease in primary hypertensive patients, and correlate these markers with risk factors for cardiovascular disease. METHODS: A cross-sectional study was performed in 199 middle-aged adults at a basic health unit. Kidney function assessment included measurements of serum creatinine (Scr and Scys levels, 24-hour microalbuminuria (MA, as well as glomerular filtration rate (GFR through Larsson and Modification of Diet in Renal Disease (MDRD study equations. Bland- Altman plot analysis was used to calculate the agreement between equations. RESULTS: High levels of Scys were found in 22% of the patients, even with normal values of GFR estimated by MDRD study equation. Systolic blood pressure and MA correlated better with Scys than Scr, but there was no correlation between Scys and diastolic blood pressure. Gender, age > 60 years, MA, and uric acid were significantly associated with high Scys levels. After multivariate analysis, only age > 60 yrs (RR = 6.4; p OBJETIVO: Investigar a utilidade clínica da cistatina C sérica (Scys e da equação baseada na cistatina C na triagem da doença renal crônica em pacientes com hipertensão primária e correlacionar esses marcadores com fatores de risco para doença cardiovascular. MÉTODOS: Foi realizado um estudo transversal com 199 adultos de meia-idade em uma unidade básica de saúde. A avaliação da função renal incluiu medidas dos níveis séricos da creatinina (Scr e Scys, microalbuminúria de 24 h (MA, bem como da taxa de filtração glomerular (TFG por meio das equações de Larsson e do estudo MDRD. Foi utilizada a análise Bland-Altman plot para calcular a concordância entre as equações. RESULTADOS: Foram encontrados níveis elevados de Scys em 22% dos pacientes, mesmo com valores normais da TFG estimada pela equação do estudo MDRD. A pressão sist

  19. g_contacts: Fast contact search in bio-molecular ensemble data

    Science.gov (United States)

    Blau, Christian; Grubmuller, Helmut

    2013-12-01

    Short-range interatomic interactions govern many bio-molecular processes. Therefore, identifying close interaction partners in ensemble data is an essential task in structural biology and computational biophysics. A contact search can be cast as a typical range search problem for which efficient algorithms have been developed. However, none of those has yet been adapted to the context of macromolecular ensembles, particularly in a molecular dynamics (MD) framework. Here a set-decomposition algorithm is implemented which detects all contacting atoms or residues in maximum O(Nlog(N)) run-time, in contrast to the O(N2) complexity of a brute-force approach. Catalogue identifier: AEQA_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEQA_v1_0.html Program obtainable from: CPC Program Library, Queen’s University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 8945 No. of bytes in distributed program, including test data, etc.: 981604 Distribution format: tar.gz Programming language: C99. Computer: PC. Operating system: Linux. RAM: ≈Size of input frame Classification: 3, 4.14. External routines: Gromacs 4.6[1] Nature of problem: Finding atoms or residues that are closer to one another than a given cut-off. Solution method: Excluding distant atoms from distance calculations by decomposing the given set of atoms into disjoint subsets. Running time:≤O(Nlog(N)) References: [1] S. Pronk, S. Pall, R. Schulz, P. Larsson, P. Bjelkmar, R. Apostolov, M. R. Shirts, J.C. Smith, P. M. Kasson, D. van der Spoel, B. Hess and Erik Lindahl, Gromacs 4.5: a high-throughput and highly parallel open source molecular simulation toolkit, Bioinformatics 29 (7) (2013).

  20. Towards bioelectronic logic (Conference Presentation)

    Science.gov (United States)

    Meredith, Paul; Mostert, Bernard; Sheliakina, Margarita; Carrad, Damon J.; Micolich, Adam P.

    2016-09-01

    One of the critical tasks in realising a bioelectronic interface is the transduction of ion and electron signals at high fidelity, and with appropriate speed, bandwidth and signal-to-noise ratio [1]. This is a challenging task considering ions and electrons (or holes) have drastically different physics. For example, even the lightest ions (protons) have mobilities much smaller than electrons in the best semiconductors, effective masses are quite different, and at the most basic level, ions are `classical' entities and electrons `quantum mechanical'. These considerations dictate materials and device strategies for bioelectronic interfaces alongside practical aspects such as integration and biocompatibility [2]. In my talk I will detail these `differences in physics' that are pertinent to the ion-electron transduction challenge. From this analysis, I will summarise the basic categories of device architecture that are possibilities for transducing elements and give recent examples of their realisation. Ultimately, transducing elements need to be combined to create `bioelectronic logic' capable of signal processing at the interface level. In this regard, I will extend the discussion past the single element concept, and discuss our recent progress in delivering all-solids-state logic circuits based upon transducing interfaces. [1] "Ion bipolar junction transistors", K. Tybrandt, K.C. Larsson, A. Richter-Dahlfors and M. Berggren, Proc. Natl Acad. Sci., 107, 9929 (2010). [2] "Electronic and optoelectronic materials and devices inspired by nature", P Meredith, C.J. Bettinger, M. Irimia-Vladu, A.B. Mostert and P.E. Schwenn, Reports on Progress in Physics, 76, 034501 (2013).

  1. Early evaluation of cerebral metabolic rate of glucose (CMRglu) with {sup 18}F-FDG PET/CT and clinical assessment in idiopathic normal pressure hydrocephalus (INPH) patients before and after ventricular shunt placement: preliminary experience

    Energy Technology Data Exchange (ETDEWEB)

    Calcagni, Maria Lucia; Lavalle, Mariadea; Leccisotti, Lucia; Giordano, Alessandro [Universita Cattolica del Sacro Cuore, Institute of Nuclear Medicine, Rome (Italy); Mangiola, Annunziato; De Bonis, Pasquale; Anile, Carmelo [Universita Cattolica del Sacro Cuore, Institute of Neurosurgery, Rome (Italy); Indovina, Luca [Universita Cattolica del Sacro Cuore, Institute of Physics, Rome (Italy); Marra, Camillo [Universita Cattolica del Sacro Cuore, Institute of Neurology, Rome (Italy); Pelliccioni, Armando [Istituto Nazionale per l' Assicurazione contro gli Infortuni sul Lavoro (INAIL), Rome (Italy)

    2012-02-15

    We evaluated the relationships between the cerebral metabolic rate of glucose (CMRglu) measured by dynamic {sup 18}F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) and the clinical and neuropsychological assessment before and after the surgical procedure in idiopathic normal pressure hydrocephalus (INPH) patients. Eleven selected INPH patients underwent clinical assessment (modified Rankin scale, Krauss scale, Larsson categorization system and Stein-Langfitt scale), cognitive evaluation (Mini-Mental State Examination, MMSE) and dynamic {sup 18}F-FDG PET/CT scan 3 days before and 1 week after ventricular shunt placement. After shunting, the global CMRglu significantly increased (2.95 {+-} 0.44 vs 4.38 {+-} 0.68, p = 10{sup -7}) in all INPH patients with a mean percentage value of 48.7%. After shunting, no significant change was found in the Evans ratio whereas a significant decrease in all clinical scale scores was observed. Only a slight reduction in the MMSE was found. After shunting, a significant correlation between the global CMRglu value and clinical assessment was found (R {sup 2} = 0.75, p = 0.024); indeed all clinical scale scores varied (decreasing) and the CMRglu value also varied (increasing) in all INPH patients. Our preliminary data show that changes in the CMRglu are promptly reversible after surgery and that there is a relationship between the early metabolic changes and clinical symptoms, independently from the simultaneous changes in the ventricular size. The remarkable and prompt improvement in the global CMRglu and in symptoms may also have important implications for the current concept of ''neuronal plasticity'' and for the cells' reactivity in order to recover their metabolic function. (orig.)

  2. Klotho expression in long bones regulates FGF23 production during renal failure.

    Science.gov (United States)

    Kaludjerovic, Jovana; Komaba, Hirotaka; Sato, Tadatoshi; Erben, Reinhold G; Baron, Roland; Olauson, Hannes; Larsson, Tobias E; Lanske, Beate

    2017-02-09

    Circulating levels of bone-derived fibroblast growth factor 23 (FGF23) increase early during acute and chronic kidney disease and are associated with adverse outcomes. Membrane-bound Klotho acts as a permissive coreceptor for FGF23, and its expression was recently found in osteoblasts/osteocytes. We hypothesized that Klotho in bone cells is part of an autocrine feedback loop that regulates FGF23 expression during renal failure. Thus, we induced renal failure in mice with targeted deletion of Klotho in long bones. Uremic wild-type (KL(fl/fl) ) and knockout (Prx1-Cre;KL(fl/fl) ) mice both responded with reduced body weight, kidney atrophy, hyperphosphatemia, and increased bone turnover. Importantly, long bones of Prx1-Cre;KL(fl/fl) mice but not their axial skeleton failed to increase FGF23 expression as observed in uremic KL(fl/fl) mice. Consequently, Prx1-Cre;KL(fl/fl) mice had significantly lower serum FGF23 and parathyroid hormone levels, and higher renal 1-α-hydroxylase expression, serum 1,25-dihydroxyvitamin D, and calcium levels than KL(fl/fl) mice. These results were confirmed in two independent models of renal failure, adenine diet induced and 5/6 nephrectomy. Moreover, FGF23-treated bone cells required Klotho to increase FGF23 mRNA and ERK phosphorylation. In summary, our novel findings show that Klotho in bone is crucial for inducing FGF23 production upon renal failure. We propose the presence of an autocrine feedback loop in which Klotho senses the need for FGF23.-Kaludjerovic, J., Komaba, H., Sato, T., Erben, R. G., Baron, R., Olauson, H., Larsson, T. E., Lanske, B. Klotho expression in long bones regulates FGF23 production during renal failure.

  3. Vesicular uptake and exocytosis of l-aspartate is independent of sialin

    Science.gov (United States)

    Morland, Cecilie; Nordengen, Kaja; Larsson, Max; Prolo, Laura M.; Farzampour, Zoya; Reimer, Richard J.; Gundersen, Vidar

    2013-01-01

    The mechanism of release and the role of l-aspartate as a central neurotransmitter are controversial. A vesicular release mechanism for l-aspartate has been difficult to prove, as no vesicular l-aspartate transporter was identified until it was found that sialin could transport l-aspartate and l-glutamate when reconstituted into liposomes. We sought to clarify the release mechanism of l-aspartate and the role of sialin in this process by combining l-aspartate uptake studies in isolated synaptic vesicles with immunocyotchemical investigations of hippocampal slices. We found that radiolabeled l-aspartate was taken up into synaptic vesicles. The vesicular l-aspartate uptake, relative to the l-glutamate uptake, was twice as high in the hippocampus as in the whole brain, the striatum, and the entorhinal and frontal cortices and was not inhibited by l-glutamate. We further show that sialin is not essential for exocytosis of l-aspartate, as there was no difference in ATP-dependent l-aspartate uptake in synaptic vesicles from sialin-knockout and wild-type mice. In addition, expression of sialin in PC12 cells did not result in significant vesicle uptake of l-aspartate, and depolarization-induced depletion of l-aspartate from hippocampal nerve terminals was similar in hippocampal slices from sialin-knockout and wild-type mice. Further, there was no evidence for nonvesicular release of l-aspartate via volume-regulated anion channels or plasma membrane excitatory amino acid transporters. This suggests that l-aspartate is exocytotically released from nerve terminals after vesicular accumulation by a transporter other than sialin.—Morland, C., Nordengen, K., Larsson, M., Prolo, L. M., Farzampour, Z., Reimer, R. J., Gundersen, V. Vesicular uptake and exocytosis of l-aspartate is independent of sialin. PMID:23221336

  4. Analyses of organochlorine pesticides residues in eels (Anguilla anguilla from Lake Garda using Gas chromatography coupled with Tandem Mass Spectrometry (GC-MS/MS.

    Directory of Open Access Journals (Sweden)

    Giuseppe Federico Labella

    2017-05-01

    Full Text Available Lake Garda is located in Insubria region, that is known for being the most populated and industrialized area of Italy (Camusso et al., 2001. Therefore, the Lake water, and also the fish species present, could be affected by environmental contamination.  European eel (Anguilla anguilla are considered as suitable matrix for biomonitoring environmental contaminants in European water (Belpaire et al., 2007, being widespread in many European waters and highly contaminated by lipophilic compounds, due to the high lipid content (up to 40% (Larsson et al., 1991. Moreover, eel is an edible species (its farming currently supplies approximately 45,000 tons/year (Nielsen et al., 2008, so it also represents a public health issue. Based on these considerations, the aim of this study was to evaluate the occurrence of fourteen organochlorine pesticides (OCs in forty-five eels (Anguilla anguilla from Lake Garda, using Accelerated Solvent Extraction (ASE procedure for the analytes extraction and Gas chromatography coupled with Tandem Mass Spectrometry (GC-MS/MS for the analysis of OCs. GC-MS/MS analysis was developed and validated according to the SANTE/11945/2015 guidelines.  Uncontaminated eel sample (previously checked for the presence of OCs and considered blank with a concentration of compounds < Limit of Detection were used for all procedure's optimization steps. For all the OCs analysed, satisfactory results were achieved. Regarding eel samples, several pesticides were detected, but DDTs (DDT and its metabolites were found with the highest prevalence (92 %. The concentration rage was from not detected (n.d. to 19000 ng g-1. Although DDTs levels in the environment are declining (Albaiges et al., 2011, they continue to bioaccumulate in tissues of human and animal and biomagnify in food chains.

  5. Cranberry juice concentrate does not significantly decrease the incidence of acquired bacteriuria in female hip fracture patients receiving urine catheter: a double-blind randomized trial

    Directory of Open Access Journals (Sweden)

    Gunnarsson AK

    2017-01-01

    Full Text Available Anna-Karin Gunnarsson,1 Lena Gunningberg,2 Sune Larsson,1 Kenneth B Jonsson1 1Institution of Surgical Sciences, Uppsala University, Uppsala, Sweden; 2Institution of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden Background: Urinary tract infection (UTI is a common complication among patients with hip fractures. Receiving an indwelling urinary catheter is a risk factor for developing UTIs. Treatment of symptomatic UTIs with antibiotics is expensive and can result in the development of antimicrobial resistance. Cranberries are thought to prevent UTI. There is no previous research on this potential effect in patients with hip fracture who receive urinary catheters. Aim: The aim of this study is to investigate whether intake of cranberry juice concentrate preoperatively decreases the incidence of postoperative UTIs in hip fracture patients that received a urinary catheter. Design: This study employed a randomized, placebo-controlled double-blind trial. Method: Female patients, aged 60 years and older, with hip fracture (n=227 were randomized to receive cranberry or placebo capsules daily, from admission, until 5 days postoperatively. Urine cultures were obtained at admission, 5 and 14 days postoperatively. In addition, Euro Qual five Dimensions assessments were performed and patients were screened for UTI symptoms. Result: In the intention-to-treat analysis, there was no difference between the groups in the proportion of patients with hospital-acquired postoperative positive urine cultures at any time point. When limiting the analysis to patients that ingested at least 80% of the prescribed capsules, 13 of 33 (39% in the placebo group and 13 of 47 (28% in the cranberry group (P=0.270 had a positive urine culture at 5 days postoperatively. However, this difference was not statistically significant (P=0.270. Conclusion: Cranberry concentrate does not seem to effectively prevent UTIs in female patients with hip fracture and

  6. Estimated Visceral Adipose Tissue, but Not Body Mass Index, Is Associated with Reductions in Glomerular Filtration Rate Based on Cystatin C in the Early Stages of Chronic Kidney Disease

    Directory of Open Access Journals (Sweden)

    Ana Karina Teixeira da Cunha França

    2014-01-01

    Full Text Available Information on the association between obesity and initial phases of chronic kidney disease (CKD is still limited, principally those regarding the influence of visceral adipose tissue. We investigated whether the visceral adipose tissue is more associated with reductions in glomerular filtration rate (GFR than total and abdominal obesity in hypertensive individuals with stage 1-2 CKD. A cross-sectional study was implemented which involved 241 hypertensive patients undergoing treatment at a primary health care facility. GFR was estimated using equations based on creatinine and cystatin C levels. Explanatory variables included body mass index (BMI, waist circumference (WC, and estimated visceral adipose tissue (eVAT. The mean age was 59.6±9.2 years old and 75.9% were female. According to BMI, 28.2% of subjects were obese. Prevalence of increased WC and eVAT was 63.9% and 58.5%, respectively. Results from the assessment of GFR by BMI, WC, and eVAT categories showed that only women with increased eVAT (≥150 cm2 had a lower mean GFR by Larsson (P=0.016, Levey 2 (P=0.005, and Levey 3 (P=0.008 equations. The same result was not observed when the MDRD equation was employed. No association was found between BMI, WC, eVAT, and GFR using only serum creatinine. In the early stages of CKD, increased eVAT in hypertensive women was associated with decreased GFR based on cystatin C.

  7. Sensitivity to environmental irritants and quality of life in COPD

    Directory of Open Access Journals (Sweden)

    Ternesten-Hasséus E

    2011-12-01

    Full Text Available Ewa Ternesten-Hasséus, Sven Larsson, Eva MillqvistDepartment of Internal Medicine/Respiratory Medicine and Allergology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, SwedenAbstract: It is a common clinical experience that patients with chronic obstructive pulmonary disease (COPD complain of airway symptoms provoked by environmental irritants like chemicals and scents, although few studies can confirm such connections. The aim was to study the prevalence of airway symptoms induced by chemicals and scents in a group of patients with newly diagnosed CPOD and to analyze any relation to illness severity and quality of life. Eighty-one patients with COPD were recruited to the study. By mail they were asked to answer three questionnaires regarding symptoms, quality of life, and social and emotional influence of airway symptoms induced by environmental irritants. A majority (62% of the COPD patients claimed to be hyperreactive to chemicals and scents. As a group they scored higher on a questionnaire measuring social and emotional influences of such environmental irritants compared to healthy control subjects. Further, high scores were more common among patients with a very severe form of COPD and among patients with regular use of β2-stimulants. High scores were also associated with significantly more airway symptoms and, in some aspects, with impaired quality of life. In conclusion, the results of this study show that airway symptoms induced by environmental irritants are common in patients with COPD and that this increased airway sensitivity follows the impairment of lung capacity. The mechanisms behind this remain unclear.Keywords: COPD, hyperresponsiveness, environmental irritants, sensory hyperreactivity, quality of life

  8. A validated disease specific prediction equation for resting metabolic rate in underweight patients with COPD

    Directory of Open Access Journals (Sweden)

    Anita Nordenson

    2010-09-01

    Full Text Available Anita Nordenson2, Anne Marie Grönberg1,2, Lena Hulthén1, Sven Larsson2, Frode Slinde11Department of Clinical Nutrition, Sahlgrenska Academy at University of Gothenburg, Göteborg, Sweden; 2Department of Internal Medicine/Respiratory Medicine and Allergology, Sahlgrenska Academy at University of Gothenburg, SwedenAbstract: Malnutrition is a serious condition in chronic obstructive pulmonary disease (COPD. Successful dietary intervention calls for calculations of resting metabolic rate (RMR. One disease-specific prediction equation for RMR exists based on mainly male patients. To construct a disease-specific equation for RMR based on measurements in underweight or weight-losing women and men with COPD, RMR was measured by indirect calorimetry in 30 women and 11 men with a diagnosis of COPD and body mass index <21 kg/m2. The following variables, possibly influencing RMR were measured: length, weight, middle upper arm circumference, triceps skinfold, body composition by dual energy x-ray absorptiometry and bioelectrical impedance, lung function, and markers of inflammation. Relations between RMR and measured variables were studied using univariate analysis according to Pearson. Gender and variables that were associated with RMR with a P value <0.15 were included in a forward multiple regression analysis. The best-fit multiple regression equation included only fat-free mass (FFM: RMR (kJ/day = 1856 + 76.0 FFM (kg. To conclude, FFM is the dominating factor influencing RMR. The developed equation can be used for prediction of RMR in underweight COPD patients.Keywords: pulmonary disease, chronic obstructive, basal metabolic rate, malnutrition, body composition

  9. Groundwater targeting in a hard-rock terrain using fracture-pattern modeling, Niva River basin, Andhra Pradesh, India

    Science.gov (United States)

    Srinivasa Rao, Y.; Reddy, T. V. K.; Nayudu, P. T.

    2000-09-01

    In hard-rock terrain, due to the lack of primary porosity in the bedrock, joints, fault zones, and weathered zones are the sources for groundwater occurrence and movement. To study the groundwater potential in the hard-rock terrain and drought-prone area in the Niva River basin, southern Andhra Pradesh state, India, Landsat 5 photographic data were used to prepare an integrated hydrogeomorphology map. Larsson's integrated deformation model was applied to identify the various fracture systems, to pinpoint those younger tensile fracture sets that are the main groundwater reservoirs, and to understand the importance of fracture density in groundwater prospecting. N35°-55°E fractures were identified as tensile and N35°-55°W fractures as both tensile and shear in the study area. Apparently, these fractures are the youngest open fractures. Wherever N35°-55°E and N35°-55°W fracture densities are high, weathered-zone thickness is greater, water-table fluctuations are small, and well yields are high. Groundwater-potential zones were delineated and classified as very good, good to very good, moderate to good, and poor. Résumé. Dans les roches de socle, l'absence de porosité primaire dans la roche fait que les fractures, les zones de faille et les zones d'altération sont les sites où l'eau souterraine est présente et s'écoule. Pour étudier le potentiel en eau souterraine dans la région de socle sujette à la sécheresse du bassin de la rivière Niva (sud de l'État d'Andhra Pradesh, Inde), des données photographiques de Landsat 5 ont été utilisées pour préparer une carte hydro-géomorphologique. Le modèle intégré de déformation de Larssons a été mis en œuvre pour identifier les différents systèmes de fractures, pour mettre l'accent sur les ensembles de fractures en extension les plus jeunes qui constituent les principaux réservoirs d'eau souterraine, et pour comprendre l'importance de la densité de fractures pour la prospection de l

  10. FOREWORD: 2nd International Workshop on New Computational Methods for Inverse Problems (NCMIP 2012)

    Science.gov (United States)

    Blanc-Féraud, Laure; Joubert, Pierre-Yves

    2012-09-01

    , reduced models for the inversion, non-linear inverse scattering, image reconstruction and restoration, applications (bio-medical imaging, non-destructive evaluation etc). NCMIP 2012 was a one-day workshop. Each of the submitted papers was reviewed by 2 to 4 reviewers. Among the accepted papers, there are 8 oral presentations and 5 posters. Three international speakers were invited for a long talk. This second edition attracted 60 registered attendees in May 2012. NCMIP 2012 was supported by Institut Farman (ENS Cachan) and endorsed by the following French research networks (GDR ISIS, GDR Ondes, GDR MOA, GDR MSPC). The program committee acknowledges the following laboratories CMLA, LMT, LSV, LURPA, SATIE, as well as DIGITEO Network. Laure Blanc-Féraud and Pierre-Yves Joubert Workshop Co-chairs Laure Blanc-Féraud, I3S laboratory, CNRS, France Pierre-Yves Joubert, IEF laboratory, Paris-Sud University, CNRS, France Technical Program Committee Alexandre Baussard, ENSTA Bretagne, Lab-STICC, France Marc Bonnet, ENSTA, ParisTech, France Jerôme Darbon, CMLA, ENS Cachan, CNRS, France Oliver Dorn, School of Mathematics, University of Manchester, UK Mário Figueiredo, Instituto Superior Técnico, Lisbon, Portugal Laurent Fribourg, LSV, ENS Cachan, CNRS, France Marc Lambert, L2S Laboratory, CNRS, SupElec, Paris-Sud University, France Anthony Quinn, Trinity College, Dublin, Ireland Christian Rey, LMT, ENS Cachan, CNRS, France Joachim Weickert, Saarland University, Germany Local Chair Alejandro Mottini, Morpheme group I3S-INRIA Sophie Abriet, SATIE, ENS Cachan, CNRS, France Béatrice Bacquet, SATIE, ENS Cachan, CNRS, France Reviewers Gilles Aubert, J-A Dieudonné Laboratory, CNRS and University of Nice-Sophia Antipolis, France Alexandre Baussard, ENSTA Bretagne, Lab-STICC, France Laure Blanc-Féraud, I3S laboratory, CNRS, France Marc Bonnet, ENSTA, ParisTech, France Jerôme Darbon, CMLA, ENS Cachan, CNRS, France Oliver Dorn, School of Mathematics, University of Manchester, UK G

  11. FOREWORD: 3rd International Workshop on New Computational Methods for Inverse Problems (NCMIP 2013)

    Science.gov (United States)

    Blanc-Féraud, Laure; Joubert, Pierre-Yves

    2013-10-01

    aspects of inversion, Bayesian estimation, kernel methods, learning methods, convex optimization, free discontinuity problems, metamodels, proper orthogonal decomposition, reduced models for the inversion, non-linear inverse scattering, image reconstruction and restoration, and applications (bio-medical imaging, non-destructive evaluation...). NCMIP 2013 was a one-day workshop held in May 2013 which attracted around 60 attendees. Each of the submitted papers has been reviewed by three reviewers. Among the accepted papers, there are seven oral presentations, five posters and one invited poster (On a deconvolution challenge presented by C Vonesch from EPFL, Switzerland). In addition, three international speakers were invited to present a longer talk. The workshop was supported by Institut Farman (ENS Cachan, CNRS) and endorsed by the following French research networks (GDR ISIS, GDR Ondes, GDR MOA, GDR MSPC). The program committee acknowledges the following research laboratories CMLA, LMT, LSV, LURPA, SATIE. Laure Blanc-Féraud and Pierre-Yves Joubert Workshop co-chair Laure Blanc-Féraud, I3S laboratory and INRIA Nice Sophia-Antipolis, France Pierre-Yves Joubert, IEF, Paris-Sud University, CNRS, France Technical program committee Gilles Aubert, J-A Dieudonné Laboratory, CNRS and University of Nice-Sophia Antipolis, France Nabil Anwer, LURPA, ENS Cachan, France Alexandre Baussard, ENSTA Bretagne, Lab-STICC, France Marc Bonnet, ENSTA, ParisTech, France Antonin Chambolle, CMAP, Ecole Polytechnique, CNRS, France Oliver Dorn, School of Mathematics, University of Manchester, UK Cécile Durieu, SATIE, ENS Cachan, CNRS, France Gérard Favier, I3S Laboratory, University of Nice Sophia-Antipolis, France Mário Figueiredo, Instituto Superior Técnico, Lisbon, Portugal Laurent Fribourg, LSV, ENS Cachan, CNRS, France Marc Lambert, L2S Laboratory, CNRS, SupElec, Paris-Sud University, France Dominique Lesselier, L2S Laboratory, CNRS, SupElec, Paris-Sud University, France Matteo

  12. Conhecimento - solidariedade como um saber docente na modalidade EAD: atitudes, valores e condições / Solidarity here know how a teaching in modalidade EAD: attitudes, values and conditions

    Directory of Open Access Journals (Sweden)

    Regina Trilho Otero Xavier

    2007-01-01

    Full Text Available O presente artigo relata uma investigação que pesquisa a construção do conhecimento-solidariedade em EaD. O objetivo principal do estudo é contribuir para a implementação de ações pedagógicas em EaD na perspectiva do conhecimentosolidariedade.A partir, principalmente, dos referenciais de Boaventura Santos, JeanPiaget e Yves de La Taille procura-se compreender o que vem a ser o conhecimentosolidariedade, bem como os valores e saberes que favorecem seu desenvolvimento em ações pedagógicas de professores e alunos em EaD. Os estudos apontam que agir de acordo com o conhecimento-solidariedade exige competência cognitiva (saber sersolidário, competência afetiva (querer ser solidário e, ainda, um contexto favorável (poder ser solidário. As conclusões evidenciam que o conhecimento–solidariedade, em ações pedagógicas na modalidade EaD, está fortemente vinculado aos saberes éticos, técnicos, pedagógicos, comunicacionais e de gestão; que se trata de um saber construído progressivamente, em experiências permeadas por respeito mútuo, reciprocidade e empatia, tendo a cooperação como principal estratégia. Mas, e fundamentalmente, que ocorrência de ações, na perspectiva do conhecimento-solidariedade, é dependente decontextos individuais de origem complexa, pois envolvem a interação de vários aspectos interligados (como: hábitos, valores, sentimentos, capacidades,... e de contextos coletivos dinâmicos (como ambientes cooperativos ou coercitivos, entre pares ou “superiores”, na presença de autoridade que incentiva ou que desfavorece a solidariedade.Abstract This article reports on an investigation that the search of knowledge-building solidarity in EaD. The main objective of the study is to contribute to the implementation of educational activities in EaD the perspective of knowledge-solidarity. From mainly on the benchmarks of Boaventura Santos, Jean Piaget and Yves de La Taille seeks to understand what has to be

  13. Teatro Municipal, en Gelsenkirchen

    Directory of Open Access Journals (Sweden)

    Ruhnau, Werner

    1963-10-01

    Full Text Available Two very up to date principles have been tried at Gelsenkirchen, namely that of «transformable theatre», and the integration of the style of a building with that of the town and the landscape. Following these principles, two municipal theatres have been built, one seating 1,050 and the other 450 spectators. They are situated in the centre of the city, and constitute the nucleus of a new cultural centre in the midst of a highly industrial town; This is a project not aimed at any particular social group, but placed at the service of every man with an intellectual or artistic interest. These two buildings have reinforced concrete structures, metal roofs, and the trusses are protected against Are by means of a special asbestos treatment. Efficient air conditioning ducts are taken inside suspended concrete tubing, which run over the main theatre hall. This air conditioning produces no audible noise. The «transformability» of the theatre presented other difficult accoustical problems, which were overcome by means of plates which osciIate and open out. Aluminium laminas, with a large number of tiny holes to absorb noise, have also been fitted. These two buildings involve a close cooperation between the plastic artist and the architect. A number of works by Paul Dierkes and Yves Klein are placed inside these theatres. Externally. they are adorned with a concrete sculpture by Robert Adams, seeking to express the power of the spirit over matter.Dos principios muy de actualidad —de «teatro transformable» y de integración de la arquitectura en la ciudad y paisaje— han sido intentados en Gelsenkirchen, donde se construyeron dos teatros municipales: uno con 1.050 localidades y otro con 450. Emplazados en el centro de la ciudad, constituyen, como el núcleo de un nuevo foro, una obra al servicio del arte, del espíritu, en medio de una urbe industrial: una obra destinada no a una determinada clase social, sino para cada hombre interesado intelectual

  14. [History of the department of Psychiatry at the University of Montreal].

    Science.gov (United States)

    Stip, Emmanuel

    2015-01-01

    team at the Hôpital Louis-H. Lafontaine (now IUSMM). Significant advances related to the interaction between the psychoanalytic movement and community psychiatry were greatly influenced by the work at the Pavillon Albert-Prévost and the emergence of behavioral therapies (Dr. Yves Lamontagne) and cognitive studies conducted by the Hôpital Louis-H. Lafontaine. Great discoveries about sleep were performed at the Hôpital du Sacré-Coeur de Montréal by teams gathered around Jacques-Yves Montplaisir.We also recall that two ministers from the Quebec government with important political responsibilities were members or directors of the Département de psychiatrie. These are Drs. Camille Laurin and Denis Lazure.The Département aims to strengthen clinical and basic research by contributing new knowledge that will improve care for people with mental disorders. These efforts benefit both patients and the medical students and residents being trained to care for them. The Département remains committed to its program, to pre-doctoral education (ensuring that all medical students at the Université are trained to recognize, diagnose, and be familiar with treatment options for mental disorders), to post-doctoral education for future psychiatrists, and to the care of Quebec's patients.For over 50 years, the academic department has played a key role in attracting and recruiting excellent academic and clinical resources to staff the programs and services of our hospital partners.

  15. A ATIVIDADE DO TRABALHO COMO MEIO PARA MANUTENÇÃO DA SAÚDE DOCENTE: UMA PERSPECTIVA ERGOLÓGICA. WORK ACTIVITY AS A WAY OF MAINTAINING TEACHER’S HEALTH: AN ERGOLOGIC PERSPECTIVE

    Directory of Open Access Journals (Sweden)

    Vieira Júnior, Paulo Roberto

    2011-11-01

    Full Text Available Este artigo é produto de dissertação de mestrado, construída a partir de uma abordagem qualitativa e exploratória que analisou estratégias para manutenção da saúde pela atividade docente. Para tal realizou entrevistas semiestruturadas com seis professores do Ensino Fundamental de duas escolas da região metropolitana de Belo Horizonte - MG que desde a posse no cargo de professor não se afastaram de suas atividades por motivos de doença. As crescentes estatísticas de desordem física e emocional que atingem essa categoria desencadeadora de sucessivos pedidos de licença médica e até abandono da profissão (Síndrome de Burnout, bem como a necessidade da busca de soluções para estes fenômenos justificaram sua realização. Seu objetivo geral foi descobrir quais as estratégias utilizadas por estes docentes para manutenção da saúde. Os relatos foram analisados por meio do referencial ergológico proposto pelo filósofo francês Yves Schwartz e sua equipe. A partir desta perspectiva concluiu-se que os “professores saudáveis” criam e recriam constantemente estratégias para solucionar problemas no cotidiano laboral. No hiato entre a subjetividade e as normas antecedentes do trabalho, os educadores produzem renormalizações que explicam o êxito que logram na luta em prol da busca e manutenção da saúde e dessa forma não aumentem as estatísticas de adoecimento docente no Brasil. This article is the product of a qualitative study that discussed strategies for health maintenance by teaching. For this, semi-structured interviews were conducted with six elementary school teachers from two schools in the metropolitan region of Belo Horizonte – MG who did not need sick leave since they started working as teachers in those institutions. The increasing statistics of physical and emotional disorders that reach that category, triggering successive requests for sick leave and even abandonment of the profession, as well as the need

  16. Delayed postural control during self-generated perturbations in the frail older adults

    Directory of Open Access Journals (Sweden)

    Kubicki A

    2012-02-01

    Full Text Available Alexandre Kubicki1–3, François Bonnetblanc1,2, Geoffroy Petrement3, Yves Ballay1,2, France Mourey2,4¹UFR STAPS, Université de Bourgogne, Dijon, France; ²Motricité et Plasticité, Institut National de la Santé et de la Recherche Médicale (INSERM, Dijon, France; ³SARL Fovea Interactive, Campus Industriel – Espace Entreprises, Chalon sur Saône, France; 4UFR Médecine, Université de Bourgogne, Dijon, FrancePurpose: The aim of this study was to investigate the coordination between posture and movement in pathological aging (frailty in comparison with normal aging, with the hypothesis that in pathological aging, postural control evolves towards a more reactive mode for which the perturbation induced by the movement is not anticipated and leads to delayed and late postural adjustments.Methods: Elderly subjects performed rapid focal arm-raising movements towards a target, from an upright standing position in two stimuli conditions: simple reaction time and choice reaction time (CRT. Hand and center of pressure (CoP kinematics were compared between a control group and a frail group of the same age.Results: In frail individuals, the entire movement was impaired and slowed down. In addition, postural adjustments that classically precede and accompany the focal arm movement were delayed and reduced, especially in the CRT condition in which the motor prediction is more limited. Finally, a correlation between the time to CoP maximal velocity and the timed up-and-go score was observed.Conclusion: In these patients, it was concluded that the control of the CoP displacement evolved from a proactive mode in which the perturbation associated with the arm movement is anticipated toward a more reactive mode in which the perturbation is compensated by late and delayed adjustments.Keywords: frailty, anticipatory postural adjustments, backward disequilibrium

  17. Tissue inhibitor of matrix metalloproteinases-1 loaded poly(lactic-co-glycolic acid nanoparticles for delivery across the blood–brain barrier

    Directory of Open Access Journals (Sweden)

    Chaturvedi M

    2014-01-01

    Full Text Available Mayank Chaturvedi,1 Yves Molino,2 Bojja Sreedhar,3 Michel Khrestchatisky,4 Leszek Kaczmarek1 1Laboratory of Neurobiology, Nencki Institute, Warsaw, Poland; 2Vect-Horus, Marseille, France; 3Indian Institute of Chemical Technology, Hyderabad, India; 4Aix-Marseille Université, CNRS, NICN, UMR7259, Marseille, France Aim: The aim of this study was to develop poly(lactic-co-glycolic acid (PLGA nanoparticles (NPs for delivery of a protein – tissue inhibitor of matrix metalloproteinases 1 (TIMP-1 – across the blood–brain barrier (BBB to inhibit deleterious matrix metalloproteinases (MMPs. Materials and methods: The NPs were formulated by multiple-emulsion solvent-evaporation, and for enhancing BBB penetration, they were coated with polysorbate 80 (Ps80. We compared Ps80-coated and uncoated NPs for their toxicity, binding, and BBB penetration on primary rat brain capillary endothelial cell cultures and the rat brain endothelial 4 cell line. These studies were followed by in vivo studies for brain delivery of these NPs. Results: Results showed that neither Ps80-coated nor uncoated NPs caused significant opening of the BBB, and essentially they were nontoxic. NPs without Ps80 coating had more binding to endothelial cells compared to Ps80-coated NPs. Penetration studies showed that TIMP-1 NPs + Ps80 had 11.21%±1.35% penetration, whereas TIMP-1 alone and TIMP-1 NPs without Ps80 coating did not cross the endothelial monolayer. In vivo studies indicated BBB penetration of intravenously injected TIMP-1 NPs + Ps80. Conclusion: The study demonstrated that Ps80 coating of NPs does not cause significant toxic effects to endothelial cells and that it can be used to enhance the delivery of protein across endothelial cell barriers, both in vitro and in vivo. Keywords: PLGA nanoparticles, drug delivery, protein delivery, sustained release, brain delivery, BBB penetration, RBCEC culture

  18. 《美容整形外科》(Aesthetic Plastic Surgery)2001年第25卷第4期目录

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Aesthetic Plastic Surgery Volume 25 , Number 4, 2001 249 The Value of a New Filler Material in Corrective and Cosmetic Surgery: DermaLive and DermaDeep Catherine Bergeret-Galley , Xavier Latouche , Yves-Gérard Illouz 256 Fat Transplantation for Soft Tissue Augmentation in the Lower Limbs M. Stampos, P. Xepoulias 262 The Effect of Reduction of the Peripheral Fat Content by Liposuction-Assisted Lipectomy (SAL) on Serum Leptin Levels in the Postoperative Period: A Prospective Study Ran Talisman, Nik Belinson, Dalit Modan-Moses, Hana Canti, Arie Orenstein, Zohar,Barzilai, Gideon Parret 266 Short Columella Nasolabial Complex in Aesthetic Rhinoplasty A. Aldo Mottura 273 Nasal Reconstruction After Epithelioma Salvador Rodriguez-Camps 278 PVP Breast Implants After Two Years: Initial Results of a Prospective Study Henrik Menke , H. GrUbmeyer, E. Biemer, R. R. Olbrisch 283 Mammographic Findings Following Reduction Mammoplasty Dimitrios Danikas, Spero J. V. Theodorou, George Kokkalis, Katerina Vasiou, Konstantina K yriakopoulou 286 Unsatisfactory Results of Periareolar Mastopexy With or Without Augmentation and Reduction Mammoplasty: Enlarged Areola With Flattened Nipple Cihat N. Baran, Fatih Peker , Turgut Ortak , Omer Sensoz , Namik K. Baran 290 Postoperative Compression After Breast Augmentation Bassem Nathan, Shiva Singh 292 Breast Augmentation with Fresh-Frozen Homologous Fat Grafts J. Haik, R. Talisman, J. Tamir, J. Frand, E. Gazit, J. Schibi, A. Glicksman, A. Orenstein 295 Upper Eyelid Mycobacterial Infection Following Oriental Blepharoplasty in a Pulmonary Tuberculosis Patient Samuel H. T. Chen, Chun-Hua Wang, Hung-Chi Chen, George C. J. Weng, Paul-Yann Lin, Fu-Chan Wei 299 Clinical Facial Photography in a Small Office:Lighting Equipment and Technique Fabio Meneghini 307 Specific Requirements for Preoperative and Postoperative Photos Used in Publication Irene Talamas and Luis Pando 311 Announcements

  19. COMMITTEES: LISA 7 Science Organizing Committee and Local Organizing Committee LISA 7 Science Organizing Committee and Local Organizing Committee

    Science.gov (United States)

    2009-05-01

    Science Organising Committee (SOC) Pierre Binetruy, APC - College de France Massimo Cerdonio, University of Padova Karsten Danzmann, AEI/University of Hannover Mike Cruise, University of Birmingham Jim Hough, University of Glasgow Oliver Jennrich, ESTEC Philippe Jetzer, University Zurich Alberto Lobo (Chair), ICE-CSIC and IEEC Yannick Mellier, IAP, Paris Bernard Schutz, AEI Potsdam Tim Sumner, Imperial College, London Jean-Yves Vinet, OCA, Nice Stefano Vitale, University of Trento Peter Bender, University of Colorado Sasha Buchman, Stanford University Joan Centrella, NASA/Goddard Neil Cornish, Montana State University Curt Cutler, NASA/JPL Sam Finn, Penn State University Jens Gundlach, NPL Craig Hogan, University of Washington Scott Hughes, MIT Piero Madau, Lick Observatory Tom Prince, NASA/JPL Sterl Phinney, Caltech Doug Richstone, University of Michigan Tuck Stebbins, NASA/Goddard Kip Thorne, Caltech Roger Blandford, Stanford University Eugenio Coccia, University of Roma-2 Carlos F Sopuerta,ICE-CSIC and IEEC Enrique Garcia-Berro, Universitat Politècnica de Catalunya, Barcelona Seiji Kawamura, National Observatory, Japan Jay Marx, LIGO Laboratory Stephen Merkowitz, NASA/Goddard Benoit Mours, Laboratoire d'Annec Gijs Nelemans, IMAPP, Nijmegen Enric Verdaguer, University of Barcelona Clifford M Will, Washington University, St Louis Local Organising Committee (LOC) Anna Bertolín (IEEC) Priscilla Cañizares (ICE-CSIC and IEEC) Carlos F Sopuerta (ICE-CSIC and IEEC) Ivan Lloro (ICE-CSIC and IEEC),Chair Alberto Lobo (ICE-CSIC and IEEC) Nacho Mateos (ICE-CSIC and IEEC) Pilar Montes (IEEC) Miquel Nofrarias (IEEC) Juan Ramos-Castro (Universitat Politècnica de Catalunya) Josep Sanjuán (IEEC)

  20. Uma abordagem da Psicologia do Trabalho, na presença do trabalh

    Directory of Open Access Journals (Sweden)

    Carlos Eduardo Carrusca Vieira

    2007-06-01

    Full Text Available O pr e s ent e a r t i g o di s cut e fundament o s e pr e s supo s i ç õ e sf r e qüent ement e ut i l i z ado s c omo pont o de pa r t ida pa r a acompreensão dos fenômenos ligados ao trabalho, que o colocamcomo um mero “apêndice”. Com base na discussão dos conceitosde trabalho prescrito e trabalho real, dos marcos teóricometodológicos da ergonomia, ergologia e da psicologia materialista,o texto aponta as implicações problemáticas de tais perspectivas eapresenta a abordagem da Psicologia do Trabalho, para a qual aexperiência do trabalho real e dos trabalhadores se configura comoc a t e g o r i a c e n t r a l n a c o m p r e e n s ã o d a s u b j e t i v i d a d e , d odesenvolvimento do sujeito e dos processos de saúde/doença, comoa concebe Yves Clot. Relata-se aqui a experiência do projeto depesquisa/extensão “Conexões de Saberes sobre o Trabalho”,realizado na perspectiva metodológica da “Comunidade CientíficaAmpliada” e do “Dispositivo Dinâmico a Três Pólos”. Discutemse os fatores que conduzem ao assédio moral, que, analisado sob aó t i c a d o “ t r a b a l h o r e a l” , é r e c o n f i g u r a d o c omo “a s s é d i opsicossocial”.

  1. Photoactive TiO2 antibacterial coating on surgical external fixation pins for clinical application

    Directory of Open Access Journals (Sweden)

    Villatte G

    2015-05-01

    Full Text Available Guillaume Villatte,1,2 Christophe Massard,1 Stéphane Descamps,1,2 Yves Sibaud,1 Christiane Forestier,3 Komla-Oscar Awitor1 1Laboratory C-Biosenss EA 4676, Clermont-Ferrand University, Université d’Auvergne, Clermont-Ferrand, France; 2Department of Orthopedics, Clermont-Ferrand University Hospital (CHU, Clermont-Ferrand, France; 3Laboratory Microorganism UMR 6023, Clermont-Ferrand University, Université d’Auvergne, Clermont-Ferrand, France Abstract: External fixation is a method of osteosynthesis currently used in traumatology and orthopedic surgery. Pin tract infection is a common problem in clinical practice. Infection occurs after bacterial colonization of the pin due to its contact with skin and the local environment. One way to prevent such local contamination is to create a specific coating that could be applied in the medical field. In this work, we developed a surface coating for external fixator pins based on the photocatalytic properties of titanium dioxide, producing a bactericidal effect with sufficient mechanical strength to be compatible with surgical use. The morphology and structure of the sol-gel coating layers were characterized using, respectively, scanning electron microscopy and X-ray diffraction. The resistance properties of the coating were investigated by mechanical testing. Photodegradation of acid orange 7 in aqueous solution was used as a probe to assess the photocatalytic activity of the titanium dioxide layers under ultraviolet irradiation. The bactericidal effect induced by the process was evaluated against two strains, ie, Staphylococcus aureus and multiresistant Staphylococcus epidermidis. The coated pins showed good mechanical strength and an efficient antibacterial effect after 1 hour of ultraviolet irradiation. Keywords: hybrid sol-gel, external pin fixation, titanium dioxide, antibacterial effect, mechanical strength, ultraviolet photoactivity

  2. “Once Upon A Time”: The Efficiency of Storytelling in Shaping Drama Series, A Case Study on Bab El Hara

    Directory of Open Access Journals (Sweden)

    Joelle Chamieh

    2016-12-01

    Full Text Available We all know the enigma that compels us to dive into the excitement and vivacity of a certain story we are reading or a series we are watching. The characters become a part of us and the streets, café shops, etc., design our thoughts and dreams as they display the ‘vitrines’ of our reality. All is triggered by a simple word “once upon a time.” In this article, we go in-depth by analyzing storytelling and by exploring the significant role of the character as positioned in a text. However, our main concern is the possibility of being able to decipher values transmitted by a text, where the character plays a major role in terms of reflecting empathy/sympathy towards audiences’ perceptions. We, therefore, came with the idea of designing an innovative value analysis framework – based on Pierre Glaudes’s and Yves Reuter’s grid analysis pattern for value depiction – where two studies that analyze the famous series Bab El Hara, are cross referenced. Then, in order to test the validity of the framework, an original qualitative analysis based on a focus group session is conducted on ten Lebanese respondents (aged between 35 and 45 who relate their personal opinions and beliefs in terms of what they perceive in Bab El Hara, giving, therefore, indication to what values they identify with the most. Effectively, the values which respondents did identify with seemed to correspond perfectly with the value analysis framework which has shown to be a suitable base for value depiction.

  3. Nursing intuition: a valid form of knowledge.

    Science.gov (United States)

    Green, Catherine

    2012-04-01

    An understanding of the nature and development of nursing intuition can help nurse educators foster it in young nurses and give clinicians more confidence in this aspect of their knowledge, allowing them to respond with greater assurance to their intuitions. In this paper, accounts from philosophy and neurophysiology are used to argue that intuition, specifically nursing intuition, is a valid form of knowledge. The paper argues that nursing intuition, a kind of practical intuition, is composed of four distinct aspects that include: (1) embodied knowledge rather like that knowledge we have when we have learned to ride a bicycle; (2) well-trained sensory perceptions attentive to subtle details of complex, often rapidly changing situations; (3) a significant store of pertinent conceptual knowledge; and (4) a history of habitual actions intentionally directed towards achieving the best outcomes for our patients. Contemporary neurophysiology research strongly suggests that human persons experience other persons such that they directly understand the meaning of a variety of different human actions, intentions, emotions, and sensations in immediate, non-reflective, and non-conceptual perceptions. This research is supported by the philosophical theories of Jacques Maritain and Yves R. Simon found in their accounts of practical knowledge. Together, these accounts offer us a rich view of the reality of nursing intuition that helps us understand why we find intuitive actions in some but not all nurses and gives us some specific information about how to develop intuition in young nurses. Finally, this research shows us a path for further research. © 2012 Blackwell Publishing Ltd.

  4. Integration of Ferroelectrics, Ferromagnets, and Multiferroics with Silicon

    Science.gov (United States)

    Schlom, Darrell

    2009-03-01

    In this talk I will describe the epitaxial integration of ferroelectrics, ferromagnets, and materials that are both at the same time, with silicon. Until recently, ``oxide'' could only mean one thing to anyone working in the semiconductor industry---SiO2. But oxides are an exciting class of electronic materials in their own right. Oxides exhibit the full spectrum of electronic, optical, and magnetic behavior including many functionalities not found in conventional semiconductors. Further, such oxides can be combined epitaxially not only with each other, but epitaxially with the workhorse of semiconductor technology, silicon, enabling the unparalleled variety of physical properties of oxides to be exploited in new ways for electronic applications. The specific oxides that my collaborators* and I have integrated epitaxially with silicon include EuO, ZnO, CaTiO3, SrTiO3, BaTiO3, BiFeO3, Pb(Zr,Ti)O3, and PbMg1/3Nb2/3O3-PbTiO3. Highlights from these systems will be presented. * The work reported was performed in collaboration with the groups of Jochen Mannhart (U. Augsburg), Chang-Beom Eom (U. Wisconsin-Madison), Ramamoorthy Ramesh (Berkeley), Jeremy Levy (U. Pittsburgh), David Muller (Cornell), Xiaoqing Pan (U. Michigan), J"urgen Schubert (J"ulich), Long-Qing Chen (Penn State), Susan Trolier-McKinstry (Penn State), Yves Idzerda (Montana State), Peter B"oni (TU M"unchen), Joseph Woicik (NIST), Philip Ryan (Ames), Michael Bedzyk (Northwestern), Yuri Barash (Russian Acad. Sci.), Qing Ma (Intel), and Hao Li (Motorola).

  5. CONHECIMENTO-SOLIDARIEDADE COMO UM SABER DOCENTE NA MODALIDADE EAD: ATITUDES, VALORES E CONDIÇÕES

    Directory of Open Access Journals (Sweden)

    Regina Trilho Otero Xavier

    2008-07-01

    Full Text Available O presente artigo relata uma investigação que pesquisa a construção do conhecimento-solidariedade em EAD. O objetivo principal do estudo é contribuir para a implementação de ações pedagógicas em EAD na perspectiva do conhecimento-solidariedade. A partir, principalmente, dos referenciais de Boaventura Santos, Jean Piaget e Yves de La Taille procura-se compreender o que vem a ser o conhecimento-solidariedade, bem como os valores e saberes que favorecem seu desenvolvimento em ações pedagógicas de professores e alunos em EAD. Os estudos apontam que agir de acordo com o conhecimento-solidariedade exige competência cognitiva (saber ser solidário, competência afetiva (querer ser solidário e, ainda, um contexto favorável (poder ser solidário. As conclusões evidenciam que o conhecimento–solidariedade, em ações pedagógicas na modalidade EAD, está fortemente vinculado aos saberes éticos, técnicos, pedagógicos, comunicacionais e de gestão; que se trata de um saber construído progressivamente, em experiências permeadas por respeito mútuo, reciprocidade e empatia, tendo a cooperação como principal estratégia. Mas, e fundamentalmente, que a ocorrência de ações, na perspectiva do conhecimento-solidariedade, é dependente de contextos individuais de origem complexa, pois envolvem a interação de vários aspectos interligados (como: hábitos, valores, sentimentos, capacidades,... e de contextos coletivos dinâmicos (como ambientes cooperativos ou coercitivos, entre pares ou “superiores”, na presença de autoridade que incentiva ou que desfavorece a solidariedade. Palavras-chave: EaD, solidariedade, saberes docentes.

  6. A prospective case series evaluating the safety and efficacy of the Klox BioPhotonic System in venous leg ulcers

    Directory of Open Access Journals (Sweden)

    Nikolis A

    2016-09-01

    Full Text Available Andreas Nikolis,1 Doria Grimard,2 Yves Pesant,3 Giovanni Scapagnini,4 Denis Vézina5 1Division of Plastic Surgery, Victoria Park Research Centre, Montreal, 2Q&T Research Chicoutimi, Chicoutimi, 3St-Jerome Medical Research Inc., St-Jerome, Quebec, Canada; 4Department of Medicine and Health Sciences, School of Medicine, University of Molise, Campobasso, Italy; 5Klox Technologies, Laval, Quebec, Canada Purpose: To investigate the safety and efficacy of the BioPhotonic System developed by Klox Technologies in a case series of ten patients with venous leg ulcers.Patients and methods: Ten patients with chronic venous leg ulcers, having failed on at least one previous therapy, were enrolled into this case series.Results: Nine patients were evaluable for efficacy. A response (defined as decrease in wound surface area was observed in seven patients (77.8%. Of these, four patients (44.4% achieved wound closure on average 4 months (127.5 days following the beginning of the treatment. Two patients did not respond to the investigational treatment. Quality of life improved over time throughout the study. Compliance was excellent, with 93.2% of visits completed as per protocol. Safety was unremarkable, with only four treatment-emergent-related adverse events, for which no specific intervention was required.Conclusion: The BioPhotonic System was shown to be safe and extremely well tolerated. It also demonstrated potential in terms of wound closure, wound surface area decrease, and wound bed preparation. Keywords: biophotonics, light, photobiomodulation, venous leg ulcers

  7. “玩自己”的皮普时装

    Institute of Scientific and Technical Information of China (English)

    Gnna

    2009-01-01

    <正>说到肖像图案不得不提大名鼎鼎的波普艺术。上世纪五六十年代,Andy Warhol引领波普艺术横空出世。它颠覆了古典艺术的创作思路,集合通俗流行、商业、趣味等元素于一身,Warhol最著名的作品之一即是运用丝网印刷"Mass Productions"(大量复制)的一众名人形象。从此,玩乐般的偶像崇拜就蔓延开来也使得肖像图案同夸张的卡通、幽默标语、报纸印刷图案,随手涂鸦,连环画等一起,成为了典型的波普艺术图案。渗透进社会各个层面的波普艺术也对时装影响至深,主要表现在对传统时装材质以及图案的波普式改良上。在推出包含了一点笑料和波普艺术精神的"蒙德里安"系列后,Yves Saint Lauren于1971年最早开始将Picasso女儿的侧影绘制在件上世纪40年代风格的连身裙上。Gianni Versace印满一条长裙的

  8. ROMANIAN FOLKLORE MOTIFS IN FASHION DESIGN

    Directory of Open Access Journals (Sweden)

    MOCENCO Alexandra

    2014-05-01

    Full Text Available The traditional Romanian costume such as the entire popular art (architecture, woodcarvins, pottery etc. was born and lasted in our country since ancient times. Closely related to human existence, the traditional costume reflected over the years as reflected nowadays, the mentality and artistic conception of the people. Today the traditional Romanian costume became an inspiration source to the wholesale fashion production industry designers, both Romanian and international. Although the contemporary designers are working in accordance with a vision, using a wide area of styles, methods and current technology, they usually return to traditional techniques and ethnic folklore motifs, which converts and resize them, integrating them in their contemporary space. Adrian Oianu is a very appreciated Romanian designer who launched two collections inspired by his native’s country traditional costumes: “Suflecata pan’ la brau” (“Turned up ‘til the belt” and “Bucurie” (“Joy”. Dorin Negrau had as inspiration for his “Lost” collection the traditional costume from the Bihor region. Yves Saint Laurent had a collection inspired by the Romanian traditional flax blouses called “La blouse roumaine”. The paper presents the traditional Romanian values throw fashion collections. The research activity will create innovative concepts to support the garment industry in order to develop their own brand and to bring the design activities in Romania at an international level. The research was conducted during the initial stage of a project, financed through national founds, consisting in a documentary study on ethnographic characteristics of the popular costume from different regions of the country.

  9. Synthetic biology for pharmaceutical drug discovery

    Directory of Open Access Journals (Sweden)

    Trosset JY

    2015-12-01

    Full Text Available Jean-Yves Trosset,1 Pablo Carbonell2,3 1Bioinformation Research Laboratory, Sup’Biotech, Villejuif, France; 2Faculty of Life Sciences, SYNBIOCHEM Centre, Manchester Institute of Biotechnology, University of Manchester, Manchester, UK; 3Department of Experimental and Health Sciences (DCEXS, Research Programme on Biomedical Informatics (GRIB, Hospital del Mar Medical Research Institute (IMIM, Universitat Pompeu Fabra (UPF, Barcelona, Spain Abstract: Synthetic biology (SB is an emerging discipline, which is slowly reorienting the field of drug discovery. For thousands of years, living organisms such as plants were the major source of human medicines. The difficulty in resynthesizing natural products, however, often turned pharmaceutical industries away from this rich source for human medicine. More recently, progress on transformation through genetic manipulation of biosynthetic units in microorganisms has opened the possibility of in-depth exploration of the large chemical space of natural products derivatives. Success of SB in drug synthesis culminated with the bioproduction of artemisinin by microorganisms, a tour de force in protein and metabolic engineering. Today, synthetic cells are not only used as biofactories but also used as cell-based screening platforms for both target-based and phenotypic-based approaches. Engineered genetic circuits in synthetic cells are also used to decipher disease mechanisms or drug mechanism of actions and to study cell–cell communication within bacteria consortia. This review presents latest developments of SB in the field of drug discovery, including some challenging issues such as drug resistance and drug toxicity. Keywords: metabolic engineering, plant synthetic biology, natural products, synthetic quorum sensing, drug resistance

  10. Power port contrast medium flushing and trapping: impact of temperature, an in vitro experimental study

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    Guiffant G

    2013-09-01

    Full Text Available Gérard Guiffant,1 Jean Jacques Durussel,1 Patrice Flaud,1 Laurent Royon,1 Pierre Yves Marcy,2 Jacques Merckx1,31University Paris Diderot, Paris, France; 2Radiodiagnosis and Interventional Radiology Department, Caen, France; 3University Teaching Hospital Necker-Enfants Malades, Paris, FrancePurpose: The use of totally implantable venous access devices (TIVADs certified as "high pressure resistant" or "power port" has begun to spread worldwide as a safe procedure for power contrast injection. Owing to the thermo-rheological properties of the contrast media, the primary aim of this work is to present an in vitro experimental impact study concerning the impact of the temperature level on flushing efficiency after contrast medium injection. Moreover, we report experimental data that confirms the role of needle bevel orientation. The secondary aim is to answer the following questions: Is there significant device contrast medium trapping after contrast medium injection? Is saline flushing efficient? And, finally, is it safe to inject contrast medium through an indwelled port catheter?Results: The experimental results show that in addition to hydrodynamics, temperature is a key parameter for the efficiency of device flushing after contrast medium injection. It appears that this is the case when the cavity is incompletely rinsed after three calibrated flushing volumes of 10 mL saline solution, even by using the Huber needle bevel opposite to the port exit. This leads to a potentially important trapped volume of contrast medium in the port, and consequently to the possibility of subsequent salt precipitates and long term trisubstituted benzene nuclei delivery that might impair the solute properties, which may be further injected via the power port later on.Conclusion: We thus suggest, in TIVADS patients, the use of a temporary supplementary intravenous line rather than the port to perform contrast medium injections in daily radiology routine practice

  11. NIHSS and acute complications after anterior and posterior circulation strokes

    Directory of Open Access Journals (Sweden)

    Godefroy O

    2012-02-01

    Full Text Available Mathieu Boone1, Jean-Marc Chillon2, Pierre-Yves Garcia1, Sandrine Canaple1, Chantal Lamy1, Olivier Godefroy1,3, Jean-Marc Bugnicourt1,2,31Department of Neurology, Amiens University Hospital, Amiens, France, 2INSERM ERI-12, and University of Picardie, 3Laboratory of Functional Neurosciences and Pathology (EA 4559, Amiens, FranceBackground: The purpose of this study was to determine whether the National Institutes of Health Stroke Scale (NIHSS score was associated with inhospital neurological and medical complications (NMC in patients with posterior circulation infarction.Methods: This retrospective study included all patients admitted to our stroke unit during a one-year period (n = 289. NMC included neurological deterioration (ie, worsening by 4 points or more of the NIHSS score during the hospital stay and all other medical complications based on what was recorded in the patients' charts.Results: Seventy-nine patients (27% experienced NMC. In posterior circulation infarction patients (n = 90, patients with NMC had a higher baseline NIHSS score (10.9 versus 2.2, P = 0.004 and a baseline NIHSS score >2 (78% versus 36%, P = 0.003. In stepwise logistic regression, an NIHSS score >2 (odds ratio: 8.2; 95% confidence interval: 1.64–41.0; P = 0.01 was associated with NMC. Similar results were observed for anterior circulation infarction patients but with a higher cutoff value for NIHSS score.Conclusion: In ischemic stroke patients, an increased baseline NIHSS score was associated with an increased risk of NMC. This association applied to anterior-circulation as well as posterior circulation stroke, although zero on the NIHSS for posterior circulation stroke does not mean the absence of NMC during hospitalization. The clinical significance of these findings requires further evaluation in larger prospective studies.Keywords: acute, stroke, rating scales, complications

  12. Questões de Michel Foucault à revista Hérodote e respostas dos geógrafos

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    Ana Maria Leite de Barros

    2016-07-01

    Full Text Available Esse texto foi traduzido livremente do original em francês da Revista Hérodote, abril-junho, segundo trimestre de 1977, n.6, p.3-39, por Ana Maria Leite de Barros e teve revisão técnica de Cláudio Luiz Zanotelli. A versão original da revista foi obtida de gallica.bnf.fr/Bibliothèque Nationale de France. Trata-se de texto inédito em português. Ele é o prosseguimento lógico do primeiro dialogo estabelecido entre Foucault e os geógrafos que gravitavam entorno da Revista Herodote fundada por Yves Lacoste. Em efeito, no primeiro número de revista Hérodote, primeiro trimestre de 1976, janeiro-março, esse geógrafos apresentaram questões a Michel Foucault que as respondeu e a entrevista foi publicada nesse mesmo número (p.71-85. Essa entrevista com Michel Foucault foi traduzida no Brasil por Roberto Machado e Angela Loureiro de Souza e publicada dentre outros artigos no livro Microfísica do poder em capitulo intitulado Sobre Geografia, (Michel Foucault, Microfísica do poder, p.153-166, Rio de Janeiro: Graal, 1999 [ primeira edição em português 1979]. O dialogo ora apresentado prolonga o debate, pois desta feita é Foucault que endereça questões os geógrafos. São inúmeros geógrafos que respondem às questões, dentre eles Milton Santos, Jean-Bernard Racine e Claude Raffestin.

  13. LISA 8 Science Organizing Committee and Local Organizing Committee LISA 8 Science Organizing Committee and Local Organizing Committee

    Science.gov (United States)

    2011-05-01

    Science Organising Committee (SOC) Tom Abel, Stanford University Odylio Aguiar, Instituto Nacional de Pesquisas Espaciais Tal Alexander, Wizemann Institute Peter Bender, University of Colorado Pierre Binetruy, APC - College de France Sasha Buchman, Stanford University Robert Byer, Stanford University Manuela Campanelli, University of Texas Joan Centrella, NASA/Goddard Massimo Cerdonio, University of Padova Eugenio Coccia, University of Roma-2 Neil Cornish, Montana State University Michael Cruise, University of Birmingham Curt Cutler, NASA/JPL Karsten Danzmann, University of Hannover Sam Finn, Penn State University Jens Gundlach, NPL Gerhard Heinzel, Max-Planck-Institut fuer Gravitationsphysik Craig Hogan, University of Washington Jim Hough, University of Glasgow Scott Hughes, MIT Oliver Jennrich, ESTEC Philippe Jetzer, University Zurich Seiji Kawamura, National Observatory, Japan Alberto Lobo, ICE-CSIC and IEEC Avi Loeb, Harvard University Piero Madau, Lick Observatory Yannick Mellier, IAP, Paris Peter Michelson, Stanford University Guido Mueller, University of Florida Sterl Phinney, Caltech Tom Prince, NASA/JPL Doug Richstone, University of Michigan Bernard Schutz, AEI Potsdam Tuck Stebbins, NASA/Goddard Tim Sumner, Imperial College, London Ke-Xun Sun, Stanford University Kip Thorne, Caltech Michele Vallisneri, NASA/JPL Alberto Vecchio, University of Birmingham Jean-Yves Vinet, OCA, Nice Stefano Vitale, University of Trento Rai Weiss, MIT Nick White, NASA/Goddard Local Organising Committee (LOC) Sasha Buchman (Stanford University) Robert Byer (Stanford University) Sara Charbonneau-Lefort (Stanford University) Nancy Christianson (Stanford University) John Conklin (Stanford University) Dan DeBra (Stanford University) Jan Goebel (Stanford University) Vivian Drew (Stanford University) Ke-Xun Sun (Stanford University) Lucy Zhou (Stanford University) Andrea Zoellner (Stanford University)

  14. Abatement of CO{sub 2} emissions in the European Union

    Energy Technology Data Exchange (ETDEWEB)

    Lesourne, J.; Keppler, J.H.; Jaureguy-Naudin, Maite; Smeers, Yves; Bouttes, Jean-Paul; Trochet, Jean-Michel; Dassa, Francois; Neuhoff, Karsten

    2008-07-01

    This first monograph of the Ifri program on European Governance and Geopolitics of Energy is devoted to the control of carbon dioxide emissions within the European Union. Since it is almost unanimously accepted that Greenhouse Gas emissions constitute the main cause of the observed increase of the world average temperature, the system implemented by the European Union to limit and decrease the CO{sub 2} emissions is a significant pillar of the EU energy policy, the two others being the acceptance by the Member States of long-term commitments (for instance on the future share of renewable energy sources in their energy balance sheet) and the establishment of an internal market for electricity and gas. Though simple in principle, the European Union Greenhouse Gas Emission Trading Scheme (EU ETS) is in fact rather complex, and only experts really understand its merits and its deficiencies. These deficiencies are real and will have to be corrected in the future for the system to be effective. At this moment, when the 2005-2007 trial phase of the EU ETS is ending, the monograph has the purpose to stimulate the discussion between experts and to enable all those interested in the topic to understand the issues and to take part in the public debates on the subject. The monograph contains five papers: - 'An Overview of the CO{sub 2} Emission Control System in the European Union' by Jacques Lesourne and Maite Jaureguy-Naudin. - 'Description and Assessment of EU CO{sub 2} Regulations' by Yves Smeers. - 'Assessment of EU CO{sub 2} Regulations' by Jean-Paul Bouttes, Jean-Michel Trochet and Francois Dassa. - 'Investment in Low Carbon Technologies, Policies for the Power Sector' by Karsten Neuhoff. - 'Lessons Learned from the 2005-2007 Trial Phase of the EU Emission Trading System' by Jan Horst Keppler

  15. Resenhas v. 4 n. 8

    Directory of Open Access Journals (Sweden)

    Amauri Carlos Ferreira

    2009-05-01

    Full Text Available SENA, Luzia (Org.. Ensino religioso e formação docente.(Religious teaching and teacher qualificationAmauri Carlos FerreiraSANGENIS, Luiz Fernando Conde. Gênese do pensamento único em educação: franciscanismo e jesuitismo na história da educação brasileira.(Genesis of an only thought in education: franciscanism and Jesuitism in the history of Brazilian educationAntônio Francisco da SilvaTREVISAN, A. Santo Tomás de Aquino – O Credo: tradução, prefácio, introdução e notas.(Saint Thomas of Aquinas – The Creed: translation, preface, introduction and notesIvonei Antônio de OliveiraBENELLI, Sílvio José. Pescadores de homens. Estudo psicossocial de um seminário católico.(Fishers of men. A psycho-social study of a Catholic seminaryJoão Batista LibanioESTRADA, Juan Antonio. A impossível teodicéia: a crise de fé em Deus e o problema do mal.(The impossible theodicy: the crisis of faith in God and the problem of evilLindomar Rocha MotaUSARSKI, Frank. Constituintes da Ciência da Religião: cinco ensaios em prol de uma disciplina.(Constituents of the science of religion: five essays on behalf of a disciplineRoberlei PanasiewiczCONGAR, Yves. Ele é o Senhor e dá a vida.(He is the Lord and bestows lifeRoberlei Panasiewicz  

  16. Effects of carbonated liquid on swallowing dysfunction in dementia with Lewy bodies and Parkinson’s disease dementia

    Directory of Open Access Journals (Sweden)

    Larsson V

    2017-08-01

    Full Text Available Victoria Larsson,1 Gustav Torisson,1,2 Margareta Bülow,3 Elisabet Londos1 1Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, 2Department of Infectious Diseases, 3Diagnostic Centre of Imaging and Functional Medicine, Skåne University Hospital, Malmö, Sweden Background: Swallowing dysfunction is an increasingly recognized problem in patients with dementia with Lewy bodies (DLB and Parkinson’s disease dementia (PDD, which can result in aspiration pneumonia and death. Few studies have examined potential ways of improving swallowing function in this fragile patient group. The aim of this study was to evaluate swallowing dysfunction and carbonated liquid using videofluoroscopy in DLB and PDD patients. Methods: A total of 48 patients with DLB and PDD were referred for a clinical examination with videofluoroscopy. Descriptive overall assessments were provided at the time of the examination regarding swallowing function and the effects of different modifications, including carbonated thin liquid (CTL. Additionally, a repeated measures quantitative retrospective analysis has been performed comparing 1 thin liquids; 2 thickened liquids and 3 CTLs, with regard to the quantitative variables 1 pharyngeal transit time (PTT; 2 pharyngeal retention and 3 tracheal penetration. Results: In all, 40/48 (83% of the patients had a swallowing dysfunction, which was confirmed on videofluoroscopy, with 34/40 (85% patients having a pharyngeal-type dysfunction. A total of 14/40 (35% patients with an objective swallowing impairment did not have any subjective swallowing symptoms. Out of the patients with swallowing dysfunction, 87% had an overall improved swallowing function with carbonated liquid. PTT for carbonated liquid (median 633 ms, interquartile range [IQR] 516–786 ms was quicker than for thin liquid (760 ms, IQR 613–940 ms, P=0.014 and thickened liquid (880.0 ms, IQR 600–1,500 ms, P<0.001. No significant effect

  17. The Danish Bladder Cancer Database

    Directory of Open Access Journals (Sweden)

    Hansen E

    2016-10-01

    Full Text Available Erik Hansen,1–3 Heidi Larsson,4 Mette Nørgaard,4 Peter Thind,3,5 Jørgen Bjerggaard Jensen1–3 1Department of Urology, Hospital of West Jutland-Holstebro, Holstebro, 2Department of Urology, Aarhus University Hospital, Aarhus, 3The Danish Bladder Cancer Database Group, 4Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, 5Department of Urology, Copenhagen University Hospital, Copenhagen, Denmark Aim of database: The aim of the Danish Bladder Cancer Database (DaBlaCa-data is to monitor the treatment of all patients diagnosed with invasive bladder cancer (BC in Denmark. Study population: All patients diagnosed with BC in Denmark from 2012 onward were included in the study. Results presented in this paper are predominantly from the 2013 population. Main variables: In 2013, 970 patients were diagnosed with BC in Denmark and were included in a preliminary report from the database. A total of 458 (47% patients were diagnosed with non-muscle-invasive BC (non-MIBC and 512 (53% were diagnosed with muscle-invasive BC (MIBC. A total of 300 (31% patients underwent cystectomy. Among the 135 patients diagnosed with MIBC, who were 75 years of age or younger, 67 (50% received neoadjuvent chemotherapy prior to cystectomy. In 2013, a total of 147 patients were treated with curative-intended radiation therapy. Descriptive data: One-year mortality was 28% (95% confidence interval [CI]: 15–21. One-year cancer-specific mortality was 25% (95% CI: 22–27%. One-year mortality after cystectomy was 14% (95% CI: 10–18. Ninety-day mortality after cystectomy was 3% (95% CI: 1–5 in 2013. One-year mortality following curative-intended radiation therapy was 32% (95% CI: 24–39 and 1-year cancer-specific mortality was 23% (95% CI: 16–31 in 2013. Conclusion: This preliminary DaBlaCa-data report showed that the treatment of MIBC in Denmark overall meet high international academic standards. The database is able to identify Danish BC patients and

  18. The Danish Testicular Cancer database

    Directory of Open Access Journals (Sweden)

    Daugaard G

    2016-10-01

    Full Text Available Gedske Daugaard,1 Maria Gry Gundgaard Kier,1 Mikkel Bandak,1 Mette Saksø Mortensen,1 Heidi Larsson,2 Mette Søgaard,2 Birgitte Groenkaer Toft,3 Birte Engvad,4 Mads Agerbæk,5 Niels Vilstrup Holm,6 Jakob Lauritsen1 1Department of Oncology 5073, Copenhagen University Hospital, Rigshospitalet, Copenhagen, 2Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, 3Department of Pathology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, 4Department of Pathology, Odense University Hospital, Odense, 5Department of Oncology, Aarhus University Hospital, Aarhus, 6Department of Oncology, Odense University Hospital, Odense, Denmark Aim: The nationwide Danish Testicular Cancer database consists of a retrospective research database (DaTeCa database and a prospective clinical database (Danish Multidisciplinary Cancer Group [DMCG] DaTeCa database. The aim is to improve the quality of care for patients with testicular cancer (TC in Denmark, that is, by identifying risk factors for relapse, toxicity related to treatment, and focusing on late effects. Study population: All Danish male patients with a histologically verified germ cell cancer diagnosis in the Danish Pathology Registry are included in the DaTeCa databases. Data collection has been performed from 1984 to 2007 and from 2013 onward, respectively. Main variables and descriptive data: The retrospective DaTeCa database contains detailed information with more than 300 variables related to histology, stage, treatment, relapses, pathology, tumor markers, kidney function, lung function, etc. A questionnaire related to late effects has been conducted, which includes questions regarding social relationships, life situation, general health status, family background, diseases, symptoms, use of medication, marital status, psychosocial issues, fertility, and sexuality. TC survivors alive on October 2014 were invited to fill in this questionnaire including 160 validated questions

  19. Long-term trends of hypoxia in the coastal zone, north-western Baltic proper

    Science.gov (United States)

    Andrén, Thomas; Norbäck Ivarsson, Lena; Andrén, Elinor

    2015-04-01

    The Baltic Sea coastal zone contains over 20 % of all identified hypoxic sites worldwide and shows an increasing trend since 1950 (Conley et al. 2011). In the open Baltic Sea, hypoxia events are recorded during three time periods: about 8000-4000, 2000-800 cal. yr. BP, and from AD 1800 up to present, but in the coastal zone data on long-term trends are lacking (Zillén et al. 2008). Different views have been proposed of what caused the oscillation in the oxygen content at sea bottoms in the open Baltic Sea e.g. changes in agricultural practice, fluctuations in human population density and climate change. The role of humans and climate in driving the eutrophication and hypoxia in the Baltic Sea needs to be understood and there is an urgent need for increased knowledge of the historical extent of hypoxia and the driving forces for formation in the coastal zone. This project aims to disentangle the role of human induced and natural climate-driven processes that have resulted in times of eutrophication and hypoxia in the Baltic Sea during the last 2000 years. Research focus is put on the coastal zone and carefully selected estuaries along the Swedish east coast, where responses to changed human land-use can be expected to be first recorded. Eight sites, from the Stockholm archipelago to Bråviken, have been cored and sediments lithologically described and dated by radiocarbon using preferably terrestrial macrofossils. Preliminary results of age models, sedimentation rates, and lithologies will be presented. Lithological descriptions using laminated sediments as a proxy for hypoxic bottom water conditions will significantly increase the knowledge on the distribution of hypoxia and the extension of areas of laminated sediments in time and space in the coastal area. References: Conley, D.J., Carstensen, J., Aigars, J., Axe, P., Bonsdorff, E., Eremina, T., Haahti, B.-M., Humborg, C., Jonsson, P., Kotta, J., Lännegren, C., Larsson, U., Maximov, A., Rodriguez Medina, M

  20. Extracellular cadmium in the bronchoalveolar space of long-term tobacco smokers with and without COPD and its association with inflammation

    Directory of Open Access Journals (Sweden)

    Sundblad BM

    2016-05-01

    Full Text Available Britt-Marie Sundblad,1,* Jie Ji,1,* Bettina Levänen,1 Klara Midander,2 Anneli Julander,2 Kjell Larsson,1 Lena Palmberg,1 Anders Lindén1 1Unit for Lung and Airway Research, 2Unit for Occupational and Environmental Dermatology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden *These authors contributed equally to this work Abstract: Tobacco contains cadmium, and this metal has been attributed a causative role in pulmonary emphysema among smokers, although extracellular cadmium has not to date been quantified in the bronchoalveolar space of tobacco smokers with or without COPD. We determined whether cadmium is enhanced in the bronchoalveolar space of long-term tobacco smokers with or without COPD in vivo, its association with inflammation, and its effect on chemokine release in macrophage-like cells in vitro. Bronchoalveolar lavage (BAL, sputum, and blood samples were collected from current, long-term smokers with and without COPD and from healthy nonsmokers. Cadmium concentrations were determined in cell-free BAL fluid using inductively coupled plasma mass spectrometry. Blood monocyte-derived macrophages were exposed to cadmium chloride in vitro. Depending upon the type of sample, molecular markers of inflammation were quantified either as protein (enzyme-linked immunosorbent assay or as mRNA (real-time polymerase chain reaction. Cadmium concentrations were markedly increased in cell-free BAL fluid of smokers compared to that of nonsmokers (n=19–29; P<0.001, irrespective of COPD. In these smokers, the measured cadmium displayed positive correlations with macrophage TNF-α mRNA in BAL, neutrophil and CD8+ cell concentrations in blood, and finally with IL-6, IL-8, and MMP-9 protein in sputum (n=10–20; P<0.05. The cadmium chloride exposure caused a concentration-dependent increase in extracellular IL-8 protein in monocyte-derived macrophages in vitro. In conclusion, extracellular cadmium is enhanced in the

  1. Existing data sources for clinical epidemiology: the Danish Quality Database of Mammography Screening

    Directory of Open Access Journals (Sweden)

    Langagergaard V

    2013-03-01

    Full Text Available Vivian Langagergaard,1 Jens P Garne,2 Ilse Vejborg,3 Walter Schwartz,4 Martin Bak,5 Anders Lernevall,1 Nikolaj B Mogensen,6 Heidi Larsson,7 Berit Andersen,1 Ellen M Mikkelsen7 1Department of Public Health Programs, Randers Hospital, Randers, Denmark; 2Department of Breast Surgery, Aalborg Hospital, Aalborg, Denmark; 3Diagnostic Imaging Center, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark; 4Center of Mammography, 5Department of Pathology, Odense University Hospital, Denmark; 6Department of Radiology, Ringsted Hospital, Ringsted, Denmark; 7Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark Abstract: The Danish Quality Database of Mammography Screening (DKMS was established in 2007, when screening was implemented on a nationwide basis and offered biennially to all Danish women aged 50–69 years. The primary aims of the database are to monitor and evaluate the quality of the screening program and – after years of follow-up – to evaluate the effect of nationwide screening on breast cancer-specific mortality. Here, we describe the database and present results for quality assurance from the first round of national screening. The steering committee for the DKMS defined eleven organizational and clinical quality indicators and standards to monitor the Danish breast cancer screening program. We calculated the relevant proportions and ratios with 95% confidence intervals for each quality indicator. All indicators were assessed on a national and regional level. Of 670,039 women invited for mammography, 518,823 (77.4% participated. Seventy-one percent of the women received the result of their mammography examination within 10 days of screening, and 3% of the participants were recalled for further investigation. Among all detected cancers, 86% were invasive cancers, and the proportion of women with node negative cancer was 67%. There were 36% women with small cancers, and the ratio of surgery for

  2. Prevalence of different pain categories based on pain spreading on the bodies of older adults in Sweden: a descriptive-level and multilevel association with demographics, comorbidities, medications, and certain lifestyle factors (PainS65+

    Directory of Open Access Journals (Sweden)

    Dragioti E

    2016-11-01

    Full Text Available E Dragioti,1 B Larsson,1 L Bernfort,2 LÅ Levin,2 B Gerdle1 1Pain and Rehabilitation Medicine, 2Division of Health Care Analysis, Department of Medical and Health Sciences (IMH, Faculty of Health Sciences, Linköping University, Linköping, Sweden Background and objective: There is limited knowledge about the prevalence of pain and its relation to comorbidities, medication, and certain lifestyle factors in older adults. To address this limitation, this cross-sectional study examined the spreading of pain on the body in a sample of 6611 subjects ≥65 years old (mean age = 75.0 years; standard deviation [SD] = 7.7 living in southeastern Sweden.Methods: Sex, age, comorbidities, medication, nicotine, alcohol intake, and physical activity were analyzed in relation to the following pain categories: local pain (LP (24.1%, regional pain medium (RP-Medium (20.3%, regional pain heavy (RP-Heavy (5.2%, and widespread pain (WSP (1.7%.Results: RP-Medium, RP-Heavy, and WSP were associated more strongly with women than with men (all p<0.01. RP-Heavy was less likely in the 80–84 and >85 age groups compared to the 65–69 age group (both p<0.01. Traumatic injuries, rheumatoid arthritis/osteoarthritis, and analgesics were associated with all pain categories (all p<0.001. An association with gastrointestinal disorders was found in LP, RP-Medium, and RP-Heavy (all p<0.01. Depressive disorders were associated with all pain categories, except for LP (all p<0.05. Disorders of the central nervous system were associated with both RP-Heavy and WSP (all p<0.05. Medication for peripheral vascular disorders was associated with RP-Medium (p<0.05, and hypnotics were associated with RP-Heavy (p<0.01.Conclusion: More than 50% of older adults suffered from different pain spread categories. Women were more likely to experience greater spreading of pain than men. A noteworthy number of common comorbidities and medications were associated with increased likelihood of pain

  3. Chronic musculoskeletal pain: review of mechanisms and biochemical biomarkers as assessed by the microdialysis technique

    Directory of Open Access Journals (Sweden)

    Gerdle B

    2014-06-01

    Full Text Available Björn Gerdle,1,2 Bijar Ghafouri,1,3 Malin Ernberg,4 Britt Larsson1,21Rehabilitation Medicine, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden; 2Pain and Rehabilitation Centre, County Council of Östergötland, Linköping, Sweden; 3Rehabilitation Medicine, Department of Medicine and Health Sciences, Linköping University, Linköping, Sweden; 4Department of Dental Medicine, Section of Orofacial Pain and Jaw Function, Karolinska Institutet, Huddinge, SwedenAbstract: Chronic musculoskeletal pain conditions are multifaceted, and approximately 20% of the adult population lives with severe chronic pain, with a higher prevalence in women and in lower income groups. Chronic pain is influenced by and interacts with physical, emotional, psychological, and social factors, and a biopsychosocial framework is increasingly applied in clinical practice. However, there is still a lack of assessment procedures based on the activated neurobiological pain mechanisms (ie, the biological part of the biopsychosocial model of pain, which may be a necessary step for further optimizing outcomes after treatments for patients with chronic pain. It has been suggested that chronic pain conditions are mainly driven by alterations in the central nervous system with little or no peripheral stimuli or nociception. In contrast, other authors argue that such central alterations are driven by peripheral alterations and nociceptive input. Microdialysis is an in vivo method for studying local tissue alterations and allows for sampling of substances in the interstitium of the muscle, where nociceptor free nerve endings are found close to the muscle fibers. The extracellular matrix plays a key role in physiologic functions of cells, including the primary afferent nociceptor. The present review mainly concerns the results of microdialysis studies and how they can contribute to the understanding of activated peripheral nociceptive and pain

  4. Detection of the Zeeman effect in atmospheric O2 using a ground-based microwave radiometer

    Science.gov (United States)

    Navas-Guzmán, Francisco; Kämpfer, Niklaus; Murk, Axel; Larsson, Richard; Buehler, Stefan A.; Eriksson, Patrick

    2015-04-01

    numerical weather prediction (NWP) models. References [1] W. B. Lenoir, "Propagation of partially polarized waves in a slightly anisotropic medium," Journal of Applied Physics, vol. 38, no. 13, pp. 5283-5290, 1967. [2] R. Larsson, S. A. Buehler, P. Eriksson, and J. Mendrok, "A treatment of the zeeman effect using stokes formalism and its implementation in the atmospheric radiative transfer simulator (ARTS)," Journal of Quantitative Spectroscopy and Radiative Transfer, vol. 133, pp. 445-453, 2014.

  5. The Danish Prostate Cancer Database

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    Nguyen-Nielsen M

    2016-10-01

    Full Text Available Mary Nguyen-Nielsen,1,2 Søren Høyer,3 Søren Friis,4 Steinbjørn Hansen,5 Klaus Brasso,6 Erik Breth Jakobsen,7 Mette Moe,8 Heidi Larsson,9 Mette Søgaard,9 Anne Nakano,9,10 Michael Borre1 1Department of Urology, Aarhus University Hospital, Aarhus, 2Diet, Genes and Environment, Danish Cancer Society Research Center, Copenhagen, 3Department of Pathology, Aarhus University Hospital, Aarhus, 4Danish Cancer Society Research Centre, Danish Cancer Society, Copenhagen, 5Department of Oncology, Odense University Hospital, Odense, 6Copenhagen Prostate Cancer Center and Department of Urology, Rigshospitalet, University of Copenhagen, Copenhagen, 7Department of Urology, Næstved Hospital, Næstved, 8Department of Oncology, Aalborg University Hospital, Aalborg, 9Department of Clinical Epidemiology, Aarhus University Hospital, 10Competence Centre for Health Quality and Informatics (KCKS-Vest, Aarhus, Denmark Aim of database: The Danish Prostate Cancer Database (DAPROCAdata is a nationwide clinical cancer database that has prospectively collected data on patients with incident prostate cancer in Denmark since February 2010. The overall aim of the DAPROCAdata is to improve the quality of prostate cancer care in Denmark by systematically collecting key clinical variables for the purposes of health care monitoring, quality improvement, and research. Study population: All Danish patients with histologically verified prostate cancer are included in the DAPROCAdata. Main variables: The DAPROCAdata registers clinical data and selected characteristics for patients with prostate cancer at diagnosis. Data are collected from the linkage of nationwide health registries and supplemented with online registration of key clinical variables by treating physicians at urological and oncological departments. Main variables include Gleason scores, cancer staging, prostate-specific antigen values, and therapeutic measures (active surveillance, surgery, radiotherapy, endocrine

  6. Book Reviews

    Directory of Open Access Journals (Sweden)

    A. Teeuw

    1961-04-01

    Full Text Available - R.J. Mohr, Carl A. Schmitz, Historische probleme in Nordost-Neuguinea. Huon-Halbinsel. Franz Steiner Verlag GMBH. Wiesbaden. 1960. 425 Pp., 43 Abbildungen, 9 karten und 1 Faltkarte. Studien zur Kulturkunde 16. Band. - P.E. de Josselin de Jong, H.G. Quaritch Wales, Prehistory and religion in South-East Asia. Bernard Quaritch Ltd., London 1957. 175 pp. text, 24 figs., 2 plates. - H.J. de Graaf, K.G. Tregonning, Under chartered company rule (North Borneo 1881-1946. University of Malaya Press, Singapore, 1958. 222 pp. tekst, 3 ills., 2 krtn. - S. Kooyman, Karl Erik Larsson, Fijian Studies. Etnologiska Studier, 25. Göteborg, 1960. 147 pag., 65 ills. - A. Teeuw, Hans Kähler, Ethnographische und linguistische studien über die Orang darat, Orang akit, Orang laut und Orang utan im Riau-Archipel und auf den Inseln an der Ostküste von Sumatra. Veröffentlichungen des Seminars für Indonesische und Südseesprachen der Universität Hamburg. Band 2. Berlin 1960. VI + 294 pp. - A. Teeuw, Ali Haji Ahmad, Puisi Baharu Melayu (Zaman Permulaan. Disusun oleh: Ali Haji Ahmad. Siri Sastera DBP. Bil. 4. Dewan Bahasa dan Pustaka....Kuala Lumpur 1959. XV + 60 pp. - A. Teeuw, William Shakespeare, Romeo dan Julia, di-terjemahkan oleh Trisno Sumardjo. Oxford University Press, Kuala Lumpur 1960. X + 150 pp. - A. Teeuw, Chepu Kenchana. Antoloji cherita2 pendek dunia. Pengenalan dan anotasi oleh Derwent May. Kata pengantar oleh Asraf. Oxford University Press, Kuala Lumpur 1960. 196 pp. - A. Teeuw, Hasan bin Muhammad Ali, Musafir. Siri Sastera DBP Bil. 3....Kuala Lumpur 1959. 142 pp. - A. Teeuw, Asraf, Mekar dan Segar. Bunga rampai cherita-cherita pendek angkatan baru. Di-pileh dan di-bicharakan oleh Asraf. Oxford University Press, Kuala Lumpur 1959. XV + 157 pp. - A. Teeuw, Cherita pendek DBP. Siri Sastera DBP Bil. 2. Dewan Bahasa dan Pustaka...Kula Lumpur 1958. 180 pp. - B.A.L. Cranstone, S. Kooyman, The art of Lake Sentani. Museum of Primitive Art, New York

  7. [Comparison of taxonomic importance of morphological and molecular-genetic characters in systematics of Microsporidia (Microsporidia) of blood-sucking mosquitoes (Diptera: Culicidae)].

    Science.gov (United States)

    Simakova, A V

    2014-01-01

    Comparative analysis of the taxonomic position of microsporidians from mosquitoes of the family Culicidae, for which SSU rDNA sequences data were obtained, demonstrates partial contradiction of systems based on morphological and phylogenetic characteristics. Representatives of the genera Anncaliia Issi. et al., 1993 and Vavraia Weiser, 1977 constitute separate evolutionary branches of the phylogenetic tree of microsporidians of blood-sucking mosquitoes. Representatives of other genera, for which the SSU rRNA sequences data were obtained (Amblyospora Hazard, Oldacre, 1975, Andreanna Simakova et al., 2008, Culicospora (Kudo, 1921), Weiser, 1977, Culicosporella Hazard, Savage, 1970, Edhazardia (Kudo, 1930), Sprague, Fucuda, 1989, Hazardia Weiser, 1977, Hyalinocysta Hazard, Oldacre, 1975, Novothelohania Andreadis et al., 2012, Parathelohania Codreanu, 1966, Senoma Simakova et al., 2005, and Trichoctosporea Larsson, 1994), form a separate, monophyletic group in the tree of Microsporidia. They are closely related and probably possess a common ancestor. The genera Amblyospora, Culicospora, Edhazardia, and Trichoctosporea were placed in the family Amblyosporidae with the revision of the diagnosis. On the basis of the obtained data on morphology and molecular phylogeny we placed Intrapredatorus barri Chen et al:, 1998 into the genus Amblyospora as Amblyospora barri, comb. nov., and also the species Amblyospora bakcharia Andreadis et al., 2012, A. kazankia Andreadis et al., 2012, A. mocrushinia Andreadis et al., 2012, and A. rugosa Simakova, Pankova, 2005 into the genus Trichoctosporea as Trichoctosporea bakcharia comb. nov., T. kazankia comb. nov., T. mocrushinia comb. nov., and T. rugosa comb. nov. Microsporidians of blood-sucking mosquitoes originally possessed complicated life cycles with transovarial and oral transmissions and with the presence of intermediate hosts (lower crustaceans). Later, some microsporidians had lost a part of their life cycle, either during

  8. Existing data sources for clinical epidemiology: Scandinavian Cohort for osteonecrosis of the jaw – work in progress and challenges

    Directory of Open Access Journals (Sweden)

    Schiodt M

    2015-01-01

    Full Text Available Morten Schiodt,1 Cecilia Larsson Wexell,2,3 Bente Brokstad Herlofson,4 Karen Marie Giltvedt,4 Sven Erik Norholt,5 Vera Ehrenstein61Department of Oral and Maxillofacial Surgery, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; 2Department of Oral and Maxillofacial Surgery, Södra Älvsborg Hospital, Region Västra Götaland, Borås, 3Department of Biomaterials, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; 4Department of Oral Surgery and Oral Medicine, Faculty of Dentistry, University of Oslo, Oslo, Norway; 5Department of Oral and Maxillofacial Surgery, Aarhus University and University Hospital, 6Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, DenmarkAbstract: Osteonecrosis of the jaw (ONJ is a severe side effect associated with antiresorptive treatment. Monitoring of ONJ using routine databases in Scandinavian countries is a challenge owing to lack of valid algorithms and to heterogeneous referral practices. The aim of this paper is to describe the process of establishing a Scandinavian ONJ Cohort enrolling all ONJ cases related to antiresorptive treatment arising in Denmark, Norway, and Sweden between 2011 and 2019. The initial purpose of the cohort is to support an ongoing pharmacovigilance study of denosumab and zoledronic acid in Denmark, Norway, and Sweden. The three countries, with their 199 clinics, departments, and units of oral and maxillofacial surgery, both hospital-based and freestanding, differ somewhat in referral practices of the ONJ patients. By directly contacting all providers of care to ONJ patients in the three countries, we established a network for reporting incident cases to each country's research database directly or through a member of the Scandinavian ONJ task force as a liaison. The task force includes a Scandinavian coordinator and three national coordinators collaborating directly with the clinics. A uniform ONJ

  9. Use of microorganisms to improve the cementation of granular structures. Applications in the restoration of monuments

    Science.gov (United States)

    González, Isabel; Mayoral, Eduardo; Ortiz, Pilar; Segura, Dolores; Vazquez, Auxiliadora; Barba, Cinta; Ortiz, Rocio; Romero, Antonio

    2015-04-01

    This researching work focuses on the development of new procedures to be applied in heritage rehabilitation, through the implementation of low-cost biotechnological processes in the realm of engineering and architecture. In doing so, it explores the possibilities of MICP (Microbially Induced Calcite Precipitation), which is a biomineralization process applied to improve the engineering properties of granular structures. This is a novelty approach at present, as there are few researches putting together knowledge in biotechnology and mineralogy to by applied in architecture and engineer. Some authors propose the bacteria use to generate habitable structures that reduce desertification (Magnus Larsson 2008). Innovative research teams led by De Jong and the University of California UC Davis (XXXX) study how cement or stabilize soils to prevent landslides, improving the foundation injecting populations of Bacillus pasteurii in the field. Bacterially induced mineralization has emerged as a method for protecting and consolidating decayed ornamental stone, which offers noticeable advantages compared to traditional restoration procedures (Tiano et al., 1999). Castanier et al. (2000) found that Bacillus cereus was able to induce extracellular precipitation of calcium carbonate on decayed limestones. Rodriguez-Navarro et al. (2003) tested the ability of Myxococcus xanthus to induce calcium carbonate precipitation. Current studies are evaluating the potential of bacteria as self-healing agents for the autonomous decrease of permeability of concrete upon crack formation (De Muynck, et al 2010) In the urban area of Seville, most historical buildings are constructed with calcarenites, limestones, sandstones and bricks, the weathering forms associated to this building materials often are granular disintegration, so the proposed technology has a huge potential to be applied to these materials for possible restoration. This research is mainly grounded on laboratory work, which

  10. Iron nanoparticles increase 7-ketocholesterol-induced cell death, inflammation, and oxidation on murine cardiac HL1-NB cells

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    Edmond Kahn

    2010-03-01

    Full Text Available Edmond Kahn1, Mauhamad Baarine2, Sophie Pelloux3, Jean-Marc Riedinger4, Frédérique Frouin1, Yves Tourneur3, Gérard Lizard21INSE RM U678/UMR – S UPMC, IFR 14, CH U Pitié-Salpêtrière, 75634 Paris Cedex 13, France; 2Centre de Recherche INSE RM U866, Equipe Biochimie Métabolique et Nutritionnelle – Université de Bourgogne, Faculté des Sciences Gabriel, 6 Bd Gabriel, 21000 Dijon, France; 3Centre Commun de Quantimétrie, Université Lyon 1; Université de Lyon, Lyon, France; 4Département de Biologie et de Pathologie des Tumeurs, Centre Georges François-Leclerc, 21000 Dijon, FranceObjective: To evaluate the cytotoxicity of iron nanoparticles on cardiac cells and to determine whether they can modulate the biological activity of 7-ketocholesterol (7KC involved in the development of cardiovascular diseases. Nanoparticles of iron labeled with Texas Red are introduced in cultures of nonbeating mouse cardiac cells (HL1-NB with or without 7-ketocholesterol 7KC, and their ability to induce cell death, pro-inflammatory and oxidative effects are analyzed simultaneously.Study design: Flow cytometry (FCM, confocal laser scanning microscopy (CLSM, and subsequent factor analysis image processing (FAMIS are used to characterize the action of iron nanoparticles and to define their cytotoxicity which is evaluated by enhanced permeability to SYTOX Green, and release of lactate deshydrogenase (LDH. Pro-inflammatory effects are estimated by ELISA in order to quantify IL-8 and MCP-1 secretions. Pro-oxidative effects are measured with hydroethydine (HE.Results: Iron Texas Red nanoparticles accumulate at the cytoplasmic membrane level. They induce a slight LDH release, and have no inflammatory or oxidative effects. However, they enhance the cytotoxic, pro-inflammatory and oxidative effects of 7KC. The accumulation dynamics of SYTOX Green in cells is measured by CLSM to characterize the toxicity of nanoparticles. The emission spectra of SYTOX Green and

  11. Nominal group technique to select attributes for discrete choice experiments: an example for drug treatment choice in osteoporosis

    Directory of Open Access Journals (Sweden)

    Hiligsmann M

    2013-02-01

    Full Text Available Mickael Hiligsmann,1-3 Caroline van Durme,2 Piet Geusens,2 Benedict GC Dellaert,4 Carmen D Dirksen,3 Trudy van der Weijden,5 Jean-Yves Reginster,6 Annelies Boonen21Department of Health Services Research, School for Public Health and Primary Care (CAPHRI, Maastricht University, The Netherlands, 2Department of Internal Medicine, CAPHRI, Maastricht University, The Netherlands, 3Department of Clinical Epidemiology and Medical Technology Assessment, CAPHRI, Maastricht University, The Netherlands, 4Department of Business Economics, Erasmus Rotterdam University, The Netherlands, 5Department of General Practice, CAPHRI, Maastricht University, The Netherlands, 6Department of Public Health, Epidemiology and Health Economics, University of Liege, BelgiumBackground: Attribute selection represents an important step in the development of discrete-choice experiments (DCEs, but is often poorly reported. In some situations, the number of attributes identified may exceed what one may find possible to pilot in a DCE. Hence, there is a need to gain insight into methods to select attributes in order to construct the final list of attributes. This study aims to test the feasibility of using the nominal group technique (NGT to select attributes for DCEs.Methods: Patient group discussions (4–8 participants were convened to prioritize a list of 12 potentially important attributes for osteoporosis drug therapy. The NGT consisted of three steps: an individual ranking of the 12 attributes by importance from 1 to 12, a group discussion on each of the attributes, including a group review of the aggregate score of the initial rankings, and a second ranking task of the same attributes.Results: Twenty-six osteoporotic patients participated in five NGT sessions. Most (80% of the patients changed their ranking after the discussion. However, the average initial and final ranking did not differ markedly. In the final ranking, the most important medication attributes were

  12. Proteomic analysis revealed alterations of the Plasmodium falciparum metabolism following salicylhydroxamic acid exposure

    Directory of Open Access Journals (Sweden)

    Torrentino-Madamet M

    2011-09-01

    Full Text Available Marylin Torrentino-Madamet1, Lionel Almeras2, Christelle Travaillé1, Véronique Sinou1, Matthieu Pophillat3, Maya Belghazi4, Patrick Fourquet3, Yves Jammes5, Daniel Parzy11UMR-MD3, Université de la Méditerranée, Antenne IRBA de Marseille (IMTSSA, Le Pharo, 2Unité de Recherche en Biologie et Epidémiologie Parasitaires, Antenne IRBA de Marseille (IMTSSA, Le Pharo, 3Centre d'Immunologie de Marseille Luminy, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Université de la Méditerranée, 4Centre d'Analyse Protéomique de Marseille, Institut Fédératif de Recherche Jean Roche, Faculté de Médecine Nord, 5UMR-MD2, Physiologie et Physiopathologie en Conditions d'Oxygénations Extrêmes, Institut Fédératif de Recherche Jean Roche, Faculté de Médecine Nord, Marseille, FranceObjectives: Although human respiratory metabolism is characterized by the mitochondrial electron transport chain, some organisms present a “branched respiratory chain.” This branched pathway includes both a classical and an alternative respiratory chain. The latter involves an alternative oxidase. Though the Plasmodium falciparum alternative oxidase is not yet identified, a specific inhibitor of this enzyme, salicylhydroxamic acid (SHAM, showed a drug effect on P. falciparum respiratory function using oxygen consumption measurements. The present study aimed to highlight the metabolic pathways that are affected in P. falciparum following SHAM exposure.Design: A proteomic approach was used to analyze the P. falciparum proteome and determine the metabolic pathways altered following SHAM treatment. To evaluate the SHAM effect on parasite growth, the phenotypic alterations of P. falciparum after SHAM or/and hyperoxia exposure were observed.Results: After SHAM exposure, 26 proteins were significantly deregulated using a fluorescent two dimensional-differential gel electrophoresis. Among these deregulated proteins

  13. La bataille des mémoires. Herinneringen aan de Slag om Algiers in Historia Magazine

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    Désirée Schyns

    2010-12-01

    Full Text Available  Entre 1971 et 1974 Yves Courrière, rédacteur en chef de l‟hebdomadaire Historia Magazine, fait paraître une série de numéros spéciaux sur la guerre d‟Algérie. La revue est un objet d‟études intéressant, parce qu‟elle ne donne pas une représentation historique („objective‟, mais plutôt mémorielle („subjective‟ de cette guerre de décolonisation. Elle donne la parole à des partisans de l‟Algérie française, mais aussi à ceux qui se sont battus pour une Algérie indépendante. Il est frappant que ce soient surtout des officiers français qui donnent leur vision sur le passé récent et douloureux. Des pages de la revue émane de temps en temps une idéologie coloniale qui n‟est pas mise en question. Ma contribution s‟insère dans le cadre plus large de l‟évolution de la mémoire de la guerre d‟Algérie et se concentre sur la bataille d‟Alger (1957 en particulier. En guise d‟exemple, j‟analyse un article du général Jacquin qui montre la vision de cet ancien militaire sur la bataille et qui met en question l‟usage de la torture par les Français. Je compare cet article au film La Bataille d'Alger (Gillo Pontecorvo, 1966, qui donne une toute autre représentation de cet épisode historique. L‟analyse et la comparaison démontrent que Historia Magazine se trouvait au coeur d‟une bataille des mémoires.

  14. Determining prognosis in acute exacerbation of COPD

    Directory of Open Access Journals (Sweden)

    Flattet Y

    2017-01-01

    Full Text Available Yves Flattet,1 Nicolas Garin,1,2 Jacques Serratrice,1 Arnaud Perrier,1 Jérome Stirnemann,1 Sebastian Carballo1 1Department of Internal Medicine, Service of General Internal Medicine, Geneva University Hospitals, Geneva, 2Service of Internal Medicine, Riviera Chablais Hospital, Monthey, Switzerland Background: Acute exacerbations are the leading causes of hospitalization and mortality in patients with COPD. Prognostic tools for patients with chronic COPD exist, but there are scarce data regarding acute exacerbations. We aimed to identify the prognostic factors of death and readmission after exacerbation of COPD.Methods: This was a retrospective study conducted in the Department of Internal Medicine of Geneva University Hospitals. All patients admitted to the hospital with a diagnosis of exacerbation of COPD between 2008 and 2011 were included. The studied variables included comorbidities, Global Initiative for Chronic Obstructive Lung Disease (GOLD severity classification, and biological and clinical parameters. The main outcome was death or readmission during a 5-year follow-up. The secondary outcome was death. Survival analysis was performed (log-rank and Cox.Results: We identified a total of 359 patients (195 men and 164 women, average age 72 years. During 5-year follow-up, 242 patients died or were hospitalized for the exacerbation of COPD. In multivariate analysis, age (hazard ratio [HR] 1.03, 95% CI 1.02–1.05; P<0.0001, severity of airflow obstruction (forced expiratory volume in 1 s <30%; HR 4.65, 95% CI 1.42–15.1; P=0.01, diabetes (HR 1.47, 95% CI 1.003–2.16; P=0.048, cancer (HR 2.79, 95% CI 1.68–4.64; P<0.0001, creatinine (HR 1.003, 95% CI 1.0004–1.006; P=0.02, and respiratory rate (HR 1.03, 95% CI 1.003–1.05; P=0.028 on admission were significantly associated with the primary outcome. Age, cancer, and procalcitonin were significantly associated with the secondary outcome.Conclusion: COPD remains of ominous prognosis

  15. Growth and Morphology of Supercritical Fluids, a Fluid Physics Experiment Conducted on Mir, Complete

    Science.gov (United States)

    Wilkinson, R. Allen

    2001-01-01

    The Growth and Morphology of Supercritical Fluids (GMSF) is an international experiment facilitated by the NASA Glenn Research Center and under the guidance of U.S. principal investor Professor Hegseth of the University of New Orleans and three French coinvestigators: Daniel Beysens, Yves Garrabos, and Carole Chabot. The GMSF experiments were concluded in early 1999 on the Russian space station Mir. The experiments spanned the three science themes of near-critical phase separation rates, interface dynamics in near-critical boiling, and measurement of the spectrum of density fluctuation length scales very close to the critical point. The fluids used were pure CO2 or SF6. Three of the five thermostats used could adjust the sample volume with the scheduled crew time. Such a volume adjustment enabled variable sample densities around the critical density as well as pressure steps (as distinct from the usual temperature steps) applied to the sample. The French-built ALICE II facility was used for these experiments. It allows tightly thermostated (left photograph) samples (right photograph) to be controlled and viewed/measured. Its diagnostics include interferometry, shadowgraph, high-speed pressure measurements, and microscopy. Data were logged on DAT tapes, and PCMCIA cards and were returned to Earth only after the mission was over. The ground-breaking near critical boiling experiment has yielded the most results with a paper published in Physical Review Letters (ref. 1). The boiling work also received press in Science Magazine (ref. 2). This work showed that, in very compressible near-critical two-phase pure fluids, a vapor bubble was induced to temporarily overheat during a rapid heating of the sample wall. The temperature rise in the vapor was 23-percent higher than the rise in the driving container wall. The effect is due to adiabatic compression of the vapor bubble by the rapid expansion of fluid near the boundary during heatup. Thermal diffusivity is low near the

  16. George Desvallières et la Grande Guerre George Desvallières and the First World War

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    Catherine Ambroselli de Bayser

    2012-03-01

    Full Text Available George Desvallières (1861-1950 took part in the 1914-18 War as battalion commander with the “Bataillon Des Vosges”, and depicted its tragic history on his return from the front. From 1883, he became a fully recognised artist with his painting being presented at all major Paris exhibitions. Founder, Vice-President, then President of the “Salon d’Automne”, he became known as a discoverer of young talents, and obtained recognition for both cubists and fauvists. At the start of the First World War, Desvallières joined up as a volunteer. Very quickly his men acknowledged him to be an unsurpassed leader, and demanded of his superiors that he be kept in his post, which was at first only a temporary appointment. Desvallières led his “chasseurs” across the Alsatian mountains for four years with determination, courage and a kindness recognised by all on the front. In March 1915, his seventeen-year- old son Daniel was killed in action a few miles away from his father. This loss affected him deeply, but thanks to his convert’s faith, he was able to sublimate this terrible ordeal. All his post-war work is centred on the theme of the soldier’s sacrifice for his country, which he assimilates to the sacrifice of Christ on the Cross. Some of his canvases are directly related to the War and to his son’s death, and his impressive wall-paintings on a similar theme made a profound impact on contemporary public opinion. The “Drapeau du Sacré-Coeur” (Banner of the Sacred Heart at the Church of Notre Dame de Verneuil (1919 was the starting point for these murals. There followed such monumental works of pictorial expression as the Saint Privat Chapel in the Gard region (1920-1925, which will be discussed in this paper, the stained-glass windows at the Douaumont Ossuary (1927, the decoration of Wittenheim Church in Alsace (1929-1931, the Chapel of the Cité Saint Yves (1931 and the Way of the Cross at the Holy Spirit Church (1935 in Paris.*

  17. Formation and ridging of flaw leads in the eastern Canadian Beaufort Sea. Special Session C06 on: “Physical, biological and biogeochemical processes associated with young thin ice types”

    Science.gov (United States)

    Prinsenberg, S. J.

    2009-12-01

    Formation and ridging of flaw leads in the eastern Canadian Beaufort Sea. Simon Prinsenberg1 and Yves Graton2 1Bedford Inst. of Oceanography, Fisheries and Oceans Canada P.O. Box1006, Dartmouth, Nova Scotia, B2Y 4A2, Canada prinsenbergs@mar.dfo-mpo.gc.ca 2Inst. National de la Recherche Scientifique-Eau, INRS-ETE University of Quebec at Quebec City, Quebec yvesgratton@eteinrs.ca During the winter of 2008, the flaw lead south of Banks Island repeatedly opened and closed representing an elongated region where periodically the large ice growth stimulates the densification of the surface layer due to salt rejection and instigates a local circulation pattern that will affect the biological processes of the region. Helicopter-borne sensors were available to monitor the aftermath of one of the rapid closing of the flaw lead into extensive elongated rubble field using a Canadian Ice breaker, CCGS Amundsen, as a logistic base. After the wind reversed a new open flaw lead 20km wide restarting a new flaw lead formation cycle. Ice thickness and surface roughness data were collected from the rubble field and adjacent open flaw lead with an Electromagnetic-Laser system. The strong wind event of April 4-5 2009 generated a large linear 1.5km wide ice rubble field up to 8-10m thick when the 60cm thick, 18km wide flaw lead was crunched into land-fast by the 1.5m thick offshore pack ice. It is expected that during rapid ice growth in a flaw lead, salt rejection increase the density of the surface water layer producing a surface depression (Low) and cyclonic circulation. In contrast at depth, the extra surface dense water produces a high in the horizontal pressure field and anti-cyclonic circulation which remains after the rapid ice growth within the flaw lead stops. One of such remnants may have been observed during the CFL-IPY winter survey.

  18. Le crime fantastique dans _Le grand saigneur_ de Rachilde

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    Vicky Gauthier

    2011-11-01

    Full Text Available Marguerite Eymery-Vallette (1860-1953 – plus connue sous son pseudonyme d’homme de lettres Rachilde et davantage encore pour la controverse qu’elle a créée avec la parution de sa troisième œuvre, Monsieur Vénus, roman matérialiste (1884 – a énormément publié tout au long de sa carrière littéraire (on dénombre plus d’une soixantaine d’œuvres : romans, nouvelles, contes, pièces de théâtre, etc.. Écrivant à une époque dite décadente, Rachilde y brille par ses œuvres subversives, abordant entre autres les pratiques sexuelles dépravées (sadomasochisme, nécrophilie, zoophilie, etc., mais surtout le crime (qu’il soit question de meurtre, de viol, de suicide, etc.. Ainsi, son personnage de prédilection est le marginal, le criminel dénué de morale. Cet article portera donc sur la façon dont le crime (et donc le criminel chez Rachilde verse dans le fantastique, plus spécifiquement dans un fantastique du monstrueux moral que je définirai dans un premier temps. Le roman de Rachilde, Le Grand Saigneur (1922, servira ensuite d’exemple significatif de ce monstrueux moral, notamment par l’étude du personnage éponyme de l’œuvre, soit le marquis Yves de Pontcroix, qui incarne ce criminel arborant les traces tant morales (tempérament sauvage et étrange que physiques (force hors du commun, pâleur de la peau, etc. de sa monstruosité. C’est donc dire que face au(x crime(x (ou au criminel le fantastique semble s’imposer de lui-même en guise d’explication : le genre humain ne peut vraisemblablement avoir quelque chose en commun avec cette monstruosité (ou ce monstre moral, pour reprendre les mots de Michel Foucault dans Les Anormaux. En somme, cet article se penchera sur la spécificité de l’écriture rachildienne, qui, dans le cas du roman Le Grand Saigneur, attribue une dimension fantastique au personnage criminel, renforçant d’autant plus la preuve de sa difformité (monstruosité et de sa

  19. Œuvre 220 : Édouard Levé d’après Nicolas Brasseur - Entretien avec Olivier Sécardin

    Directory of Open Access Journals (Sweden)

    Olivier Sécardin

    2017-06-01

    Full Text Available Nicolas Brasseur, artiste, photographe, né en 1981 à Nantes. Vit et travaille à Paris. Diplômé de l’École Nationale Supérieure des Arts Décoratifs de Paris en 2008, Nicolas Brasseur poursuit un travail documentaire au sein d’institutions françaises autour de la notion « d’images modèles ». Ses recherches l’ont amené à photographier l’hôpital, l’école et plus récemment la prison en parte-nariat avec le Centre Photographique d’Ile-de-France (CPIF.Édouard Levé, écrivain, artiste, photographe, né en 1965, mort en 2007. Diplômé de l’ESSEC, il commence à peindre en 1991, puis brûle presque toutes ses toiles avant de se consacrer à la photographie. En 1999, il réalise sa première série, Homonymes, qui propose des portraits photographiques de personnes inconnues portant des noms célèbres : Georges Bataille, Yves Klein, Henri Michaux… Il reprend le même procédé dans Amérique (2006, reportage sur des villes américaines qui portent le nom d’autres villes connues : Florence, Berlin, Paris... Il est l’auteur de plusieurs séries photographiques. Admirateur de Raymond Roussel, lecteur de Jacques Roubaud et de Raymond Queneau, Édouard Levé est aussi écrivain. OEuvres, publié en 2002 est le catalogue de 533 projets d’oeuvres d’art, installations, peintures, sculptures ou photographies imaginés dont l’artiste a « eu l’idée, mais qu’il n’a pas réalisés ». Son Autoportrait le présente en « 1600 phrases sans solution de continuité ». Trois jours avant de se donner la mort, Édouard Levé dépose chez son éditeur le manuscrit de son dernier texte, Suicide (2008.

  20. Satisfaction of hospitalized psychiatry patients: why should clinicians care?

    Directory of Open Access Journals (Sweden)

    Zendjidjian XY

    2014-04-01

    Full Text Available Xavier-Yves Zendjidjian,1,2 Karine Baumstarck,1 Pascal Auquier,1 Anderson Loundou,1 Christophe Lançon,1,2 Laurent Boyer11Public Health, Chronic Diseases and Quality of Life Research Unit, Aix-Marseille Université, 2Department of Psychiatry, La Conception Hospital, Marseille, FranceBackground: The aim of this study was to determine the relationship between inpatient satisfaction and health outcomes, quality of life, and adherence to treatment in a sample of patients with schizophrenia, while considering key sociodemographic and clinical confounding factors.Methods: This cross-sectional study was conducted in the psychiatric departments of two public university hospitals in France. The data collected included sociodemographic information, clinical characteristics, quality of life (using the 36-Item Short Form Health Survey, nonadherence to treatment (Medication Adherence Report Scale, and satisfaction (a specific self-administered questionnaire based exclusively on patient point of view [Satispsy-22] and a generic questionnaire for hospitalized patients [QSH]. Multiple linear regressions were ­performed to assess the associations between satisfaction and quality of life and between satisfaction and nonadherence. Two sets of models were performed, ie, scores on the Satispsy-22 and scores on the QSH.Results: Ninety-one patients with schizophrenia were enrolled. After adjustment for confounding factors, patients with better personal experience during hospitalization (Satispsy-22 had a better psychological quality of life (SF36-mental composite score, β=0.37; P=0.004, and patients with higher levels of satisfaction with quality of care (Satispsy-22 showed better adherence to treatment (Medication Adherence Report Scale total score, β=−0.32; P=0.021. Higher QSH scores for staff and structure index were linked to better adherence with treatment (respectively, β=−0.33; P=0.019 and β=−0.30; P=0.032, but not with quality of life

  1. A relação da escola e do Conselho Tutelar no amparo à criança

    Directory of Open Access Journals (Sweden)

    Simone Pereira dos Santos

    2011-07-01

    Full Text Available Este artigo foi desenvolvido com o objetivo de compreender as relações efetivas entre o Conselho Tutelar de Sinop e a Escola Municipal Rodrigo Damasceno a fim de traçar uma trajetória da instituição de ensino contemplando a sua importância estratégica para o futuro das crianças, com isso, tentou-se analisar os trabalhos promovidos pelo Conselho Tutelar no âmbito escolar em consonância com os papéis sociais a estes atribuídos. Por se tratar de um estudo de natureza social optou-se em realizar a pesquisa qualitativa, em que o entendimento do contexto social e cultural são essenciais para a compreensão do tema. Dentro da pesquisa qualitativa optamos por realizar um estudo de caso, isso porque os métodos nos permitem analisar mais profundamente o fenômeno pesquisado. Para o contato com os sujeitos optou-se técnica de entrevista, a mesma foi elaborada com questões semi-estruturadas, em complemento foi realizado pesquisa bibliográfica com os autores Aranha, Ariés, Yves ainda como fonte de análise a legislação vigente sobre o tema, Convenção dos direitos da Criança, Estatuto da Criança e do Adolescente, Lei de Diretrizes e Bases e Constituição Federal. A pesquisa traz como resultado a necessidade da união dos contextos Familiar, Escolar e Municipal, ao último pelas atribuições precisas e inerentes do Conselho Tutelar, convergirem, no sentido da proteção integral das crianças e adolescentes. Se tais entidades realmente convergirem em ações educativas cidadãs, os obstáculos não seriam incapazes de superação e tampouco estará indefeso o direito a educação e consequentemente o amparo à criança.Palavras-chave: educação; criança; escola; Conselho Tutelar.

  2. Welcome to Methods and Applications in Fluorescence

    Science.gov (United States)

    Birch, David; Mély, Yves; Wolfbeis, Otto S.

    2013-03-01

    vision for the journal. Methods and Applications in Fluorescence is a journal for the whole community, so do please join us in helping to give the field of fluorescence the standing it deserves by submitting your latest and most exciting work. The success of the journal depends on all of us in the field and we look forward to working with you on this exciting project. David Birch, Yves Mély and Otto S WolfbeisEditors in Chief

  3. IL-8 secretion in primary cultures of prostate cells is associated with prostate cancer aggressiveness

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    Neveu B

    2014-05-01

    Full Text Available Bertrand Neveu*, Xavier Moreel*, Marie-Pier Deschênes-Rompré, Alain Bergeron, Hélène LaRue, Cherifa Ayari, Yves Fradet, Vincent FradetDepartment of Surgery, Laval University Cancer Research Centre, CHU de Quebec Research Centre, Quebec, QC, Canada *These authors contributed equally to this workBackground: Chronic inflammation is believed to be a major factor in prostate cancer initiation and promotion and has been studied using prostate cancer cells and immortalized cell lines. However, little is known about the contribution of normal cells to the prostatic microenvironment and inflammation. We aim to study the contribution of normal prostate epithelial cells to prostate inflammation and to link the inflammatory status of normal cells to prostate cancer aggressiveness.Materials and methods: Short-term primary cell cultures of normal epithelial prostate cells were derived from prostate biopsies from 25 men undergoing radical prostatectomy, cystoprostatectomy, or organ donation. Cells were treated with polyinosinic:polycytidylic acid, a mimic of double-stranded viral RNA and a potent inducer of the inflammatory response. Secretion of interleukin (IL-8 in the cell culture medium by untreated and treated cells was measured and we determined the association between IL-8 levels in these primary cell cultures and prostate cancer characteristics. The Fligner–Policello test was used to compare the groups.Results: Baseline and induced IL-8 secretion were highly variable between cultured cells from different patients. This variation was not related to drug use, past medical history, age, or preoperative prostate-specific antigen value. Nonetheless, an elevated secretion of IL-8 from normal cultured epithelial cells was associated with prostate cancer aggressiveness (P=0.0005.Conclusion: The baseline secretion of IL-8 from normal prostate epithelial cells in culture is strongly correlated with cancer aggressiveness and may drive prostate cancer

  4. Anti-inflammatory effects of budesonide in human lung fibroblasts are independent of histone deacetylase 2

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    Wang X

    2013-08-01

    Full Text Available Xingqi Wang,1 Amy Nelson,1 Zachary M Weiler,1 Amol Patil,1 Tadashi Sato,1 Nobuhiro Kanaji,1 Masanori Nakanishi,1 Joel Michalski,1 Maha Farid,1 Hesham Basma,1 Tricia D LeVan,1 Anna Miller-Larsson,2 Elisabet Wieslander,2 Kai-Christian Muller,3 Olaf Holz,3 Helgo Magnussen,3 Klaus F Rabe,3 Xiangde Liu,1 Stephen I Rennard1 1Pulmonary, Critical Care, Sleep and Allergy Division, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, USA; 2AstraZeneca R&D Molndal, Molndal, Sweden; 3Hospital Grosshansdorf, Center for Pneumology and Thoracic Surgery, Grosshansdorf, Germany Objective and design: Reduced expression of histone deacetylase 2 (HDAC2 in alveolar macrophages and epithelial cells may account for reduced response of chronic obstructive pulmonary disease (COPD patients to glucocorticoids. HDAC2 expression and its role in mediating glucocorticoid effects on fibroblast functions, however, has not been fully studied. This study was designed to investigate whether HDAC2 mediates glucocorticoid effects on release of inflammatory cytokines and matrix metalloproteinases (MMPs from human lung fibroblasts. Methods: Human lung fibroblasts (HFL-1 cells were stimulated with interleukin (IL-1β plus tumor necrosis factor (TNF-α in the presence or absence of the glucocorticoid budesonide. Cytokines (IL-6 and IL-8 were quantified by enzyme linked immunosorbent assay (ELISA and MMPs (MMP-1 and MMP-3 by immunoblotting in culture medium. The role of HDAC2 was investigated using a pharmacologic inhibitor as well as a small interfering ribonucleic acid (siRNA targeting HDAC2. Results: We have demonstrated that budesonide concentration-dependently (10-10–10-7 M inhibited IL-6, IL-8, MMP-1, and MMP-3 release by HFL-1 cells in response to IL-1β plus TNF-a. While an HDAC inhibitor significantly blocked the inhibitory effect of budesonide on human bronchial epithelial cells (HBECs and monocytes (THP-1 cells, it did not block the inhibitory

  5. A gender difference in circulating neutrophils in malnourished patients with COPD

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    Sven Larsson

    2011-01-01

    Full Text Available Sven Larsson1, Anita Nordenson1, Pernilla Glader1, Shigemi Yoshihara2, Anders Lindén1, Frode Slinde31Department of Internal Medicine/Respiratory Medicine and Allergology, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden; 2Department of Pediatrics, Dokkyo Medical University, Tochigi, Japan; 3Department of Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, SwedenBackground: Circulating markers of inflammation in chronic obstructive pulmonary disease (COPD may correlate to disease progression and extrapulmonary complications such as malnourishment. However, surprisingly little is known about gender-related differences for circulating inflammatory markers in COPD.Purpose: To characterize differences in circulating markers of inflammation in malnourished female and male patients with COPD.Subjects: Thirty female and 11 male patients with a clinical diagnosis of COPD and malnourishment were examined. A group of control subjects without evidence of COPD was recruited for comparison of some variables.Methods: Blood samples were drawn, and the following parameters were studied: leukocytes and differential counts, C-reactive protein (CRP, tumor necrosis factor-α, interleukin (IL-6 and IL-8, myeloperoxidase (MPO, neutrophil elastase (NE, intracellular adhesion molecule-1, vascular endothelial adhesion molecule-1, and E-selectin.Results: The mean neutrophil concentration was significantly (P = 0.019 higher in female (4.5 × 109/L than in male patients with COPD (3.5 × 109/L and significantly higher than in female control subjects (3.1 × 109/L (P , 0.01, n = 85. The mean CRP values were considerably higher in female (4.9 mg/mL than in male patients with COPD (1.5 mg/mL, but the difference was not statistically significant (P = 0.20. The mean concentrations of IL-6 and IL-8 tended to be higher in female than in male patients with COPD, but these differences did not reach statistical

  6. Design and methods for a Scandinavian pharmacovigilance study of osteonecrosis of the jaw and serious infections among cancer patients treated with antiresorptive agents for the prevention of skeletal-related events

    Directory of Open Access Journals (Sweden)

    Acquavella J

    2016-07-01

    Full Text Available John Acquavella,1 Vera Ehrenstein,1 Morten Schiødt,2 Uffe Heide-Jørgensen,1 Anders Kjellman,3,4 Svein Hansen,5 Cecilia Larsson Wexell,6,7 Bente Brokstad Herlofson,8 Sven Erik Noerholt,9 Haijun Ma,10 Katarina Öhrling,11 Rohini K Hernandez,12 Henrik Toft Sørensen1 1Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark; 2Department of Oral and Maxillofacial Surgery, Rigshospitalet, Copenhagen, Denmark; 3Department of Urology, Karolinska University Hospital, 4Department of Clinical Science, Intervention, and Technology, Karolinska Institutet, Stockholm, Sweden; 5Cancer Registry of Norway, Oslo University Hospital, Oslo, Norway; 6Department of Oral and Maxillofacial Surgery, Södra Älvsborg Hospital, Borås, Sweden; 7Department of Biomaterials, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; 8Department of Oral Surgery and Oral Medicine, Faculty of Dentistry, University of Oslo, Oslo, Norway; 9Department of Oral and Maxillofacial Surgery, Aarhus University Hospital, Aarhus, Denmark; 10Global Biostatistical Science, Amgen Inc., Thousand Oaks, CA, USA; 11Clinical Development, Amgen Inc., Thousand Oaks, CA, USA; 12Center for Observational Research, Amgen Inc., Thousand Oaks, CA, USA Objective: Osteonecrosis of the jaw (ONJ is a recognized complication of potent antiresorptive therapies, especially at the doses indicated to prevent skeletal complications for cancer patients with bone metastases. This paper describes the rationale and methods for a prospective, post-authorization safety study of cancer patients treated with antiresorptive therapies. Methods: As part of a comprehensive pharmacovigilance plan, developed with regulators’ input, the study will estimate incidence of ONJ and of serious infections among adult cancer patients with bone metastases treated with denosumab (120 mg subcutaneously or zoledronic acid (4 mg intravenously, adjusted for renal function

  7. Accretion-powered Compact Binaries

    Science.gov (United States)

    Mauche, Christopher W.

    2003-12-01

    Preface; The workshop logo; A short history of the CV workshop F. A. Córdova; Part I. Observations: 1. Low mass x-ray binaries A. P. Cowley, P. C. Schmidtke, D. Crampton, J. B. Hutchings, C. A. Haswell, E. L. Robinson, K. D. Horne, H. M. Johnston, S. R. Kulkarni, S. Kitamoto, X. Han, R. M. Hjellming, R. M. Wagner, S. L. Morris, P. Hertz, A. N. Parmar, L. Stella, P. Giommi, P. J. Callanan, T. Naylor, P. A. Charles, C. D. Bailyn, J. N. Imamura, T. Steiman-Cameron, J. Kristian, J. Middleditch, L. Angelini and J. P. Noris; 2. Nonmagnetic cataclysmic variables R. S. Polidan, C. W. Mauche, R. A. Wade, R. H. Kaitchuck, E. M. Schlegel, P. A. Hantzios, R. C. Smith, J. H. Wood, F. Hessman, A. Fiedler, D. H. P. Jones, J. Casares, P. A. Charles, J. van Paradijs, E. Harlaftis, T. Naylor, G. Sonneborn, B. J. M. Hassall, K. Horne, C. A. la Dous, A. W. Shafter, N. A. Hawkins, D. A. H. Buckley, D. J. Sullivan, F. V. Hessman, V. S. Dhillon, T. R. Marsh, J. Singh, S. Seetha, F. Giovannelli, A. Bianchini, E. M. Sion, D. J. Mullan, H. L. Shipman, G. Machin, P. J. Callanan, S. B. Howell, P. Szkody, E. M. Schlegel and R. F. Webbink; 3. Magnetic cataclysmic variables C. Hellier, K. O. Mason, C. W. Mauche, G. S. Miller, J. C. Raymond, F. K. Lamb, J. Patterson, A. J. Norton, M. G. Watson, A. R. King, I. M. McHardy, H. Lehto, J. P. Osborne, E. L. Robinson, A. W. Shafter, S. Balachandran, S. R. Rosen, J. Krautter, W. Buchholz, D. A. H. Buckley, I. R. Tuoly, D. Crampton, B. Warner, R. M. Prestage, B. N. Ashoka, M. Mouchet, J. M. Bonnet-Bidaud, J. M. Hameury, P. Szkody, P. Garnavich, S. Howell, T. Kii, M. Cropper, K. Mason, J. Bailey, D. T. Wickramasinghe, L. Ferrario, K. Beuermann, A. D. Schwope, H.-C. Thomas, S. Jordan, J. Schachter, A. V. Filippenko, S. M. Kahn, F. B. S. Paerels, K. Mukai, M. L. Edgar, S. Larsson, R. F. Jameson, A. R. King, A. Silber, R. Remillard, H. Bradt, M. Ishida, T. Ohashi and G. D. Schmidt; Part II. Accretion Theory: 4. Nonmagnetic W. Kley, F. Geyer, H. Herold, H

  8. Är marknadsanpassad forskningsanknytning möjlig? Professionsutbildningar möter akademins nya krav

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    Malin Ideland

    2012-08-01

    Full Text Available Högre utbildning drar tillbaka artikeln ”Är marknadsanpassad forskningsanknytning möjlig? Professionsutbildningar möter akademins nya krav”Redaktionen för Högre utbildning har beslutat att dra tillbaka artikeln ”Är marknadsanpassad forskningsanknytning möjlig? Professionsutbildningar möter akademins nya krav” författad av Malin Ideland, Claes Malmberg, Anne-Charlotte Ek & Sandra Jönsson och publicerad i Högre utbildning nr 2, 2012, på grund av dubbelpublicering. Artikeln är en svensk version av artikeln ”The tension between marketisation and academisation in higher education” författad av Anne-Charlotte Ek, Malin Ideland, Sandra Jönsson & Claes Malmberg och publicerad online i Studies in Higher Education den 2011-10-24. Artikeln inkom till Högre utbildning den 2011-11-07 utan hänvisning från författarna till den tidigare publiceringen eller tillstånd från Studies in Higher Education för återpublicering. Högre utbildning har därför granskat och slutligen publicerat artikeln i god tro.Dubbelpublicering utan hänvisning till tidigare publicering är forskningsetiskt olämpligt och i det aktuella fallet bryter det även mot upphovsrätten. Författarna har bett redaktionen att framföra en ursäkt för det inträffade. Avsikten har varit att i ett svenskt sammanhang diskutera en för svensk högre utbildning relevant fråga. Författarna anger dålig kunskap om dubbelpublicering på olika språk och slarv med att läsa Högre utbildnings publiceringsregler som orsak till det inträffade. Redaktionen och författarna är överens om att dra tillbaka artikeln. Författarna har informerat berörda parter vid det egna lärosätet och tagit bort artikeln från den lokala databasen.Redaktionen för Högre utbildning: Anders Sonesson, Maja Elmgren, Mona Fjellström, Lars Geschwind, Maria LarssonAbstractAktuella förändringar av högre utbildning i Sverige kan karaktäriseras av två diskurser: marknadifiering och

  9. Impact of tobacco smoking on cytokine signaling via interleukin-17A in the peripheral airways

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    Levänen B

    2016-09-01

    Full Text Available Bettina Levänen,1 Pernilla Glader,2 Barbro Dahlén,3,4 Bo Billing,4 Ingemar Qvarfordt,2 Lena Palmberg,1 Kjell Larsson,1 Anders Lindén1,2,4 1Unit for Lung and Airway Research, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, 2Department of Internal Medicine & Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, 3Centre for Allergy Research, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, 4Lung Allergy Clinic, Karolinska University Hospital, Stockholm, Sweden Abstract: There is excessive accumulation of neutrophils in the airways in chronic obstructive pulmonary disease (COPD but the underlying mechanisms remain poorly understood. It is known that extracellular cytokine signaling via interleukin (IL-17A contributes to neutrophil accumulation in the airways but nothing is known about the impact of tobacco smoking on extracellular signaling via IL-17A. Here, we characterized the impact of tobacco smoking on extracellular cytokine signaling via IL-17A in the peripheral airways in long-term smokers with and without COPD and in occasional smokers before and after short-term exposure to tobacco smoke. We quantified concentrations of IL-17A protein in cell-free bronchoalveolar lavage (BAL fluid samples (Immuno-quantitative PCR and cytotoxic T-cells (immunoreactivity for CD8+ and CD3+ in bronchial biopsies. Matrix metalloproteinase-8 and human beta defensin 2 proteins were also quantified (enzyme-linked immunosorbent assay in the BAL samples. The concentrations of IL-17A in BAL fluid were higher in long-term smokers without COPD compared with nonsmoking healthy controls, whereas those with COPD did not differ significantly from either of the other groups. Short-term exposure to tobacco smoke did not induce sustained alterations in these concentrations in occasional smokers. Long-term smokers displayed higher concentrations of IL-17A than did occasional

  10. Automated oxygen titration and weaning with FreeO2 in patients with acute exacerbation of COPD: a pilot randomized trial

    Directory of Open Access Journals (Sweden)

    Lellouche F

    2016-08-01

    Full Text Available François Lellouche,1 Pierre-Alexandre Bouchard,1 Maude Roberge,1 Serge Simard,1,2 Erwan L’Her,1,3 François Maltais,1 Yves Lacasse1 1Research Centre, 2Biostatistics Department, Quebec Heart and Lung Institute, Laval University, 3Emergency Medicine, Hôtel-Dieu de Lévis, Laval University, Quebec City, QC, Canada Introduction: We developed a device (FreeO2 that automatically adjusts the oxygen flow rates based on patients’ needs, in order to limit hyperoxia and hypoxemia and to automatically wean them from oxygen. Objective: The aim of this study was to evaluate the feasibility of using FreeO2 in patients hospitalized in the respiratory ward for an acute exacerbation of COPD. Methods: We conducted a randomized controlled trial comparing FreeO2 vs manual oxygen titration in the respiratory ward of a university hospital. We measured the perception of appropriateness of oxygen titration and monitoring in both groups by nurses and attending physicians using a Likert scale. We evaluated the time in the target range of oxygen saturation (SpO2 as defined for each patient by the attending physician, the time with severe desaturation (SpO2 <85%, and the time with hyperoxia (SpO2 >5% above the target. We also recorded length of stay, intensive care unit admissions, and readmission rate. Fifty patients were randomized (25 patients in both groups; mean age: 72±8 years; mean forced expiratory volume in 1 second: 1.00±0.49 L; and mean initial O2 flow 2.0±1.0 L/min. Results: Nurses and attending physicians felt that oxygen titration and monitoring were equally appropriate with both O2 administration systems. The percentage of time within the SpO2 target was significantly higher with FreeO2, and the time with severe desaturation and hyperoxia was significantly reduced with FreeO2. Time from study inclusion to hospital discharge was 5.8±4.4 days with FreeO2 and 8.4±6.0 days with usual oxygen administration (P=0.051. Conclusion: FreeO2 was deemed as an

  11. A Po(ética da Infância e a Formação para os Valores

    Directory of Open Access Journals (Sweden)

    Joana Cavalcanti

    2010-10-01

    Bachelard’s (2001 The Poetics of Reverie and The Poetics of Space as a guide to think about childhood as a universal, permanent and fundamental stage, being the time of the inauguration of the subject and his first appropriation of the world. The dimension of Children's Literature is discussed with the dimensions of ethics and values education having in the light of the ideas of the psychologist Yves de La Taille (2006.

  12. MoMar-Demo at Lucky Strike. A near-real time multidisciplinary observatory of hydrothermal processes and ecosystems at the Mid-Atlantic Ridge

    Science.gov (United States)

    Cannat, M.; Sarradin, P.; Blandin, J.; Escartin, J.; Colaco, A.; MoMAR-Demo Scientific Party : Aron Michael, Aumont Virginie, Baillard Christian, Ballu Valérie, Barreyre Thibaut, Blandin Jérôme, Blin Alexandre, Boulart Cédric, Cannat Mathilde, Carval Thierry, Castillo Alain, Chavagnac Valérie, Coail Jean Yves, Colaço Ana, Corela Carlos, Courrier Christophe, Crawford Wayne, Cuvelier Daphné, Daniel Romuald, Dausse Denis, Escartin Javier, Fabrice Fontaine, Gabsi Taoufik, Gayet Nicolas, Guyader Gérard, Lallier François, Lecomte Benoit, Legrand Julien, Lino Silva, Miranda Miguel, Mitard Emmelyne, Pichavant Pascal, Pot Olivier, Reverdin Gilles, Rommevaux Céline, Sarradin Pierre Marie, Sarrazin Jozée, Tanguy Virginie, Villinger Heinrich, Zbinden Magali

    2011-12-01

    , pressure probes, tiltmeter, temperature probes in selected smokers, currentmeters and temperature probes in the water column), and colonization devices for time-integrated faunal studies. In this presentation we will outline the latest results of this prototype sub-sea multidisciplinary observatory system. The MoMAR-Demo Scientific Party : Aron Michael, Aumont Virginie, Baillard Christian, Ballu Valérie, Barreyre Thibaut, Blandin Jérôme, Blin Alexandre, Boulart Cédric, Cannat Mathilde, Carval Thierry, Castillo Alain, Chavagnac Valérie, Coail Jean Yves, Colaço Ana, Corela Carlos, Courrier Christophe, Crawford Wayne, Cuvelier Daphné, Daniel Romuald, Dausse Denis, Escartin Javier, Fabrice Fontaine, Gabsi Taoufik, Gayet Nicolas, Guyader Gérard, Lallier François, Lecomte Benoit, Legrand Julien, Lino Silva, Miranda Miguel, Mitard Emmelyne, Pichavant Pascal, Pot Olivier, Reverdin Gilles, Rommevaux Céline, Sarradin Pierre Marie, Sarrazin Jozée, Tanguy Virginie, Villinger Heinrich, Zbinden Magali

  13. A Comparative Study on the Sedative Effect of Oral Midazolam and Oral Promethazine Medication in Lumbar Puncture

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    Hojjat DERAKHSHANFAR

    2013-06-01

    distress from Bone marrow aspirations and lumbar punctures. Ann Pharmacother 2003;37(1:17-22.4. Ellis JA, Villeneuve K, Newhook K, Ulrichsen J. Pain Management Practices for Lumbar Punctures: Are We Consistent? J Pediatr Nurs 2007 Dec;22(6:479-87.5. Mathai A, Nazareth M, Raju RS. Preanesthetic sedation of preschool children: comparison of intranasal midazolam versus oral promethazin. Anesth Essays Res 2011;5(1:67-71.6. McCann ME, Kain ZN. The management of preoperative anxiety in children: an update. Anesth Analg 2001; 93(1: 98–105.7. Kain ZN, Caldwell-Andrews AA. Psychological preparation of children undergoing surgery. Anesth Clinic NA 2005;23:597–614.8. Wolf AR, Rosenbarum A, Kain ZN, Larsson P, Lönnqvist PA. The place of premedication in pediatric practice. Paediatr Anaesth 2009;19(9:817-28.9. Yuen VM, Hui TW, Irwin MG, Yuen MK. A Comparison of Intranasal Dexmedetomidine and Oral Midazolam for Premedication in Pediatric Anesthesia: A Double-Blinded Randomized Controlled Trial. Anesth Analg 2008;106(6:1715–21.10. Funk W, Jakob W, Riedl T, Taeger K. Oral preanaestheticmedication for children: double blind randomized study of a combination of midazplam and ketamine vs midazolam or ketamine alone. Br JAnaesth 2000;84(3:355-4011. Mazurek MS. Sedation and Analgesia for Procedures outside the Operating Room. Semin in Pediatr Surg 2004;13(3:166-173.12. Jo SH, Hong HK, Chong SH, Lee HS, Choe H. H1 antihistamine drug promethazine directly blocks hERG K+ channel. Pharmacol Res 2009;60(5:429-37.13. Gutstein HB, Johnson KL, Heard MB, Gregory GA. Oral Ketamine Preanesthetic Medication in children, Anesthesiology 1992;76(1:28-33.14. Almenrader N, Passariello M, Coccetti B, Haiber R, Pietropaoli P. Premedication in children: a comparison of oral midazolam and oral clonidine. Pediatr Anesth 2007;17(12:1143–9.15. Singh N, Pandey RK, Saksena AK, Jaiswal JN. A comparative evaluation of oral midazolam with oral sedatives as  premedication in pediatric dentistry. J Clin Pediatr

  14. Respuesta inmune innata humana al rotavirus

    Directory of Open Access Journals (Sweden)

    Juanita Angel

    2004-03-01

    una respuesta inmunosupresora (3.

    En este contexto hemos comenzado a estudiar la interacción entre el rotavirus (RV y los monocitos y CD. Para tal efecto generamos CDI y CDM a partir de monolitos de sangre periférica de adultos sanos, como fue descrito anteriormente. Analizamos el impacto del RV en el fenotipo, la viabilidad y la capacidad de replicación viral en estos 3 tipos celulares. De esta manera podremos después probar la eficacia de estas células, tratadas con el RV, para estimular LT específicos del virus. Esperamos que estos estudios nos ayuden a entender el por qué de la baja respuesta de LT específicos contra el RV circulando en sujetos infectados (4,5 y nos abran vías que faciliten el estudio de los LT específicos de RV.

     

    REFERENCIAS

    1. LANZAVECCHIA, A. AND F. SALLUSTO. Regulation of t cell immunity by dendritic cells. Cell 2001; 106: 263-266.

    2. LARSSON, M., A. S. BEIGNON AND N. BHARDWAJ. Dcvirus interplay: A double edged sword. Semin Immunol 2004; 16: 147-161.

    3. GRANELLI-PIPERNO, A. A, GOLEBIOWSKA, C. TRUMPFHELLER, F. P. SIEGAL AND R. M. STEINMAN. Hiv-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit il-10 production and t cell regulation. Proc Natl Acad Sci U S A 2004; 101: 7669-7674. Epub 2004 May 7665.

    4. JAIMES, M. C., O. L. ROJAS, A. M. GONZÁLEZ, I. CAJIAO, A. CHARPILIENNE, P. POTHIER, E. KHOLI, H. B. GREENBERG, M. A. FRANCO AND J. ANGEL. Frequencies of virus specific cd4+ and cd8+ t

  15. PREFACE: Seventh International Conference on Dissociative Recombination: Theory, Experiments and Applications

    Science.gov (United States)

    van der Zande, Wim J.

    2009-09-01

    Hamberg55. Peet Hickman 16. Daan Schram36. Oldrich Novotny56. Christiaan Jungen 17. Dahbia Talbi37. Matthias Danielson57. Jozef Varju 18. Steven Guberman38. Radek Plasil58. Juraj Glosik 19. Mats Larsson39. Richard Thomas 20. Åsa Larson40. Andreas Wolf Absent from the picture: Detlev Reiter, Brian Mitchell, Jens Hoffmann and Dave Parker

  16. PREFACE: Liquid-solid interfaces: structure and dynamics from spectroscopy and simulations Liquid-solid interfaces: structure and dynamics from spectroscopy and simulations

    Science.gov (United States)

    Gaigeot, Marie-Pierre; Sulpizi, Marialore

    2012-03-01

    Ishiyama, Hideaki Takahashi and Akihiro Morita A theoretical study of the sum frequency vibrational spectroscopy of the carbon tetrachloride/water interface Anthony J Green, Angela Perry, Preston B Moore and Brian Space Salt effects on water/hydrophobic liquid interfaces: a molecular dynamics study Chao Zhang and Paolo Carloni Density functional theory-based simulations of sum frequency generation spectra involving methyl stretching vibrations: effect of the molecular model on the deduced molecular orientation and comparison with an analytical approach F Cecchet, D Lis, Y Caudano, A A Mani, A Peremans, B Champagne and J Guthmuller Towards modelling the vibrational signatures of functionalized surfaces: carboxylic acids on H-Si(111) surfaces Conrard Giresse Tetsassi Feugmo, Benoît Champagne, Yves Caudano, Francesca Cecchet, Yves J Chabal and Vincent Liégeois

  17. PREFACE: EmerQuM 11: Emergent Quantum Mechanics 2011 (Heinz von Foerster Congress)

    Science.gov (United States)

    Grössing, Gerhard

    2012-05-01

    -statement: 'What is proved by impossibility proofs is lack of imagination.' In this sense, therefore, our task is to make use of the variety of the different approaches offered, for it is in scrutinizing each of them that a chance for further progress and understanding may emerge. The papers collected in these proceedings essentially follow the order of the plenary talks during the conference program, with the addition of the poster presentations. Prior to the contributions to EmerQuM11, the very first paper of these proceedings presents the opening lecture by Yves Couder who addressed both twin conferences with his talk on wave-particle duality in a classical system. (Although he was not able to participate personally, the contribution of Robert Carroll, a member of the academic advisory board, is included here. Regrettably, the lectures by John Bush, Marek Czachor, Mark Everitt, Felix Finster, and Lee Smolin could not be included, partly for copyright reasons.) Finally, I would like to thank Sarah Toms and Graham Douglas and their team at IOP Publishing (Bristol) for their friendly advice and help during the preparation of these proceedings. Vienna, April 2012 Gerhard Grössing

  18. Foreword

    Science.gov (United States)

    Aime, C.; Soummer, R.

    drop as a Lyot mask. The next session focused on nulling interferometry and we gather here the corresponding contribution. Two complementary reports on theory and experiment of Bracewell interferometry were made by Yves Rabbia (Theoretical aspects of Darwin) and Marc Ollivier (Experimental aspects of Darwin). Olivier Absil gave a report on the ground based nulling interferometer experiment (Effects of atmospheric turbulence on GENIE) and Valérie Weber on MAII (Nulling interferometric broadbord). A comparison between nulling and different classes of coronagraphs was made by Olivier Guyon (Coronagraphy vs. nulling). A few prospective papers have been regrouped at the end of the book: Interferometric remapped array nulling (Lyu Abe), Multiple-stage apodized Lyot coronagraph (Claude Aime and Rémi Soummer), Piston sensor using dispersed speckles (Virginie Borkowski), Principle of a coaxial achromatic interfero coronagraph (Jean Gay), Coronagraphic imaging on the VLTI with VIDA (Olivier Lardière), Phase contrast apodisation (Frantz Martinache) The last section regroups science aspects and results on sky, using high contrast imaging: Low mass companions searches using high dynamic range imaging (Jean-Luc Beuzit). The last paper by Claire Moutou (Ground-based direct imaging of exoplanets) can be read as a prospective conclusion of the Journées. C. Aime and R. Soummer

  19. PREFACE: The 15th International Conference on X-ray Absorption Fine Structure (XAFS15)

    Science.gov (United States)

    Wu, Z. Y.

    2013-04-01

    Committees and Staff Chair of the Conference Ziyu Wu International Advisory Committee Adam Hitchcock, Canada Adriano Filipponi, Italy Alain Manceau, France Alexander Soldatov, Russia Andrea Di Cicco, Italy Britt Hedman, USA Bruce Bunker, USA Calogero R. Natoli, Italy Christopher T. Chantler, Australia Frank M. F. De Groot, Netherlands Hiroyuki Oyanagi, Japan Ingolf Lindau, USA J. Mustre de Leon, México James E Penner-Hahn, USA Joaquin Garcia Ruiz, Spain John Evans, UK John J. Rehr, USA Kiyotaka Asakura, Japan Majed Chergui, Switzerland Mark Newton, UK Shiqiang Wei, P. R. China Tsun-Kong Sham, Canada Ziyu Wu, P. R. China International Program Committee Antonio Bianconi, Italy Augusto Marcelli, Italy Emad Flear Aziz, Germany Jinghua Guo, USA Joly Yves, France Masaharu Nomura, Japan Maurizio Benfatto, Italy Pieter Glatzel, France Shiqiang Wei, China Tiandou Hu, China Toshihiko Yokoyama, Japan Way-Faung Pong, Taiwan Xinyi Zhang, China Yi Xie, China Yuying Huang, China Zhonghua Wu, China Ziyu Wu, China Local Organizing Committee Bo He Fengchun Hu Haifeng Zhao Jing Zhang Meijuan Yu Qin Yu Shuo Zhang Wangsheng Chu Wei He Wei Xu Wensheng Yan Xiaomei Gong Xing Chen Yang Zou Yi Xia Zheng Jiang Zhi Xie Zhihu Sun Zhiyun Pan Additional Staff Chengxun Liu

  20. Reseñas

    Directory of Open Access Journals (Sweden)

    HC Reseñas

    2010-02-01

    Full Text Available DE LA GRATSJA, José Luis, REIG TAPIA, Alberto y MIRALLES, Ricardo (eds. Tuñón de Lara y la historiografía española. Siglo XXI. Madrid, 1999. CUENCA TORIBIO, José Manuel. Catolicismo contemporáneo de España y Europa. Encuentros y divergencias. Encuentro. Madrid, 1999. MARTÍN, Luis R (ed. Les francs-maçons dans la cité. Les cultures politiques de la Franc-maçonnerie en Europe. xixe-xxe siècle. Presses Universitaires. Rennes, 2000. CATROGA, Fernando. O Céu da Memoria. Cemitério Romántico e Culto Cívico dos Morios. Minerva. Coimbra, 1999. NARBAYEV, Nazym B. Russia and Eurasia: the Problem of the State Systems. Second Half of the Nineteenth-Early Twentieth Century. Nauka. Moscú, 1999. ESTEBAN DE VEGA, Mariano y MORALES MOYA, Antonio (eds. Los fines de siglo en España y Portugal. II Encuentro de Historia Comparada. Universidad. Jaén, 1999. BOSWELL, Laird. Rural Communism in France, 1920-1939. Cornell University Press. Ithaca y Londres, 1998. DENÉCHÈRE, Yves. La politique espagnole de la France de 1931 à 1936. Une pratique française de rapports inégaux. L'Harmattan. Paris, 1999. AYMES, Jean-René y SAIAÜN, Serge (eds. Être espagnol. Presses de la Sorbonne Nouvelle. Paris, 2000. SHUBERT, Adrian. Death and Money in the Afternoon: A History of the Spanish Bullfight. Oxford University Press. New York, 1999. RISQUES, Manel (dir., DUARTE, Ángel, RIQUER, Borja de, y ROIG ROSICH, Josep M. Historia de la Catalunya Contemporània. Portic-Biblioteca Universitaria. Barcelona, 1999. VV. AA. Clásicos sociales contemporáneos. Servicio Editorial de la Universidad del País Vasco. Bilbao, 2000. DIAZ HERNANDEZ, Onésimo. Los Marqueses de Urquijo. El apogeo de una saga poderosa y los inicios del Banco Urquijo, 1870-1931 Eunsa. Pamplona, 1999. DUARTE, Ángel. La república del emigrante. La cultura política de los españoles en Argentina (1875-1910. Milenio. Lleida, 1998. LARRÍNAGA, Carlos. Actividad económica y cambio estructural en San

  1. Selected Abstracts of the 1st Congress of joint European Neonatal Societies (jENS 2015; Budapest (Hungary; September 16-20, 2015; Session “Pulmonology”

    Directory of Open Access Journals (Sweden)

    Various Authors

    2015-09-01

    . Malhotra, K. Tan, G. Woodhead, C.A. Nold-Petry, M.F. NoldABS 40. PRENATAL THERAPY IMPROVES THE SURVIVAL OF PREMATURE INFANTS WITH CONGENITAL CHYLOTHORAX • C.J. Lee, P.N. Tsao, C.Y. Chen, W.S. Hsieh, H.C. ChouABS 41. REFERENCE RANGES OF LAMELLAR BODY COUNTS ON GASTRIC ASPIRATE IN HEALTHY TERM NEWBORNS • S. Arayici, G. Kadioglu Simsek, B. Say, N. Uras, M.Y. Oncel, E. Alyamac Dizdar, U. Buyukkagnici, S. Karahan, F.E. Canpolat, S.S. OguzABS 42. CORD BLOOD PENTRAXIN-3 LEVELS IN RESPIRATORY DISORDERS OF THE NEWBORN • M.O. Arslanoglu, E.C. Dinleyici, N. Tekin, T. Barsan Kaya, O. Aydemir, M.A. AksitABS 43. EVALUATION OF PHYSIOLOGICAL ADAPTATION OF THE LUNG TO POSTNATAL LIFE BY LUNG ULTRASOUND • M. Federici, M.G. Pattumelli, F. Feleppa, C. Gizzi, L. Massenzi, A.M. Giua, S. Sinibaldi, M. Massoud, P.V. FedericiABS 44. NON-INVASIVE MONITORING OF OXYGEN IN THE LUNGS OF NEWBORN INFANTS BY DIODE LASER • M. Larsson, P. Lundin, E. Krite Svanberg, J. Åkeson, K. Svanberg, S. Svanberg, S. Andersson-Engels, V. FellmanABS 45. CELLULAR AGING, MEASURED AS TELOMERE ATTRITION RATE, IS NOT ACCELERATED IN PRETERM INFANTS DURING THE FIRST 18 MONTHS OF LIFE • E. Henckel, Z. Haider, P. Kosma, C. Palme-Kilander, G. Roos, S. Degerman, K. BohlinABS 46. INHALED NITRIC OXIDE DECREASES MORTALITY IN INFANTS LESS THAN 28 WEEKS GESTATION FOLLOWING PRETERM PRELABOUR RUPTURE OF MEMBRANES • S. Pal, G.J. Belteki, G. Vass, T. Ibrahim, P. Clarke, Z. Molnar, Y. Singh, A.E. CurleyABS 47. PLASMA PRO-ENDOTHELIN-1 AND PRO-ATRIAL NATRIURETIC PEPTIDE AS EARLY BIOMARKERS FOR DEVELOPMENT OF BRONCHOPULMONARY DYSPLASIA IN VERY PRETERM INFANTS • R. Gerull, R. Neumann, M. Nelle, S. Schulzke, S. WellmannABS 48. TIMELY IN-HOSPITAL VACCINATION OF VLBW INFANTS REDUCES THE RATE OF BRONCHITIS AFTER DISCHARGE OF VLBW INFANTS • G. Stichtenoth, C. Härtel, E. Herting, W. Göpel; German Neonatal Network (GNNABS 49. A MURINE MODEL OF BRONCHOPULMONARY DYSPLASIA – PRELIMINARY RESULTS FROM WHOLE-GENOME mRNA EXPRESSION STUDY

  2. PREFACE: Nanosafe2010: International Conference on Safe Production and Use of Nanomaterials

    Science.gov (United States)

    Sentein, Carole; Schuster, Frédéric; Tardif, François

    2011-07-01

    matters of interest to the NanoSafety community have been debated. The success of the conference confirms the need of such a global meeting with the aim of bridging the gap between the best scientists, engineers, exhibitors and participants from countries concerned with safe and responsible nanomaterial activities. Therefore, the third edition of the International NanoSafe Conference "NanoSafe2012" will be held in Grenoble at Minatec, 13-15 November 2012. The meeting was financially supported by generous contributions from the European Commission, La Région Rhône Alpes, la Ville de Grenoble, la Metro, and partners such as CEA, INERIS, Philips, Cordouan Technologies, Nanosight, TSI, Ecomesure, GRIMM Aerosol Technik, Particle Measuring Systems, Respirex, Lux Research, Dekati, Malvern Instruments, TSE Systems, INTERTEK ICS, NANO magazine and IOP Publishing. We would like to express our thanks to all the authors for their time and genuine efforts and to the reviewers for their fruitful comments during the preparation of this volume. The Conference OrganizersCarole SenteinFrédéric SchusterFrançois Tardif Conference photographs Local Organising CommitteeCarole SENTEIN (CEA)Dominique BAGUET (CEA)Didier MOLKO (MINATEC)Audrey SCARINGELLA (MINATEC)Frédéric SCHUSTER (CEA)François TARDIF (CEA) International Advisory CommitteeChair: Frédéric SCHUSTER (CEA, FR), François TARDIF (CEA, FR)Co-chair: Georgios KATALAGARIANAKIS (EC, BE)Paul AMYOTTE (Dalhousie U., CA)Mélanie AUFFAN (CEREGE, FR)Daniel BERNARD (ARKEMA, FR)Jorge BOCZKOWSKI (INSERM, FR)Jean-Yves BOTTERO (CEREGE, FR)Jacques BOUILLARD (INERIS, FR)Jean-Philippe BOURGOIN (CEA, FR)Marie CARRIERE (CEA, FR)Krunal CHOPRA (LSFI, IN)Rolf ECKHOFF (U. Bergen, NO)Michael ELLENBECKER (U. Massachusetts, USA)Claude EMOND (U. Montréal, CA)François GENDARMES (IRSN, FR)Peter HATTO (ISO, UK)Peter HOET (KUL, BE)Jean-Pierre KAISER (Empa, CH)Olivier LE BIHAN (INERIS, FR)Tinh NGUYEN (NIST, USA)Bernd NOWACK (Empa, CH)Günter OBERDÖRSTER (U

  3. EDITORIAL: Van der Waals interactions in advanced materials, in memory of David C Langreth Van der Waals interactions in advanced materials, in memory of David C Langreth

    Science.gov (United States)

    Hyldgaard, Per; Rahman, Talat S.

    2012-10-01

    Rahman Frictional temperature rise in a sliding physisorbed monolayer of Kr/grapheneM Walker, C Jaye, J Krim and Milton W Cole How to modify the van der Waals and Casimir forces without change of the dielectric permittivityG L Klimchitskaya, U Mohideen and V M Mostepanenko Spectroscopic characterization of van der Waals interactions in a metal organic framework with unsaturated metal centers: MOF-74-MgNour Nijem, Pieremanuele Canepa, Lingzhu Kong, Haohan Wu, Jing Li, Timo Thonhauser and Yves J Chabal A theoretical study of the hydrogen-storage potential of (H2)4CH4 in metal organic framework materials and carbon nanotubesQ Li and T Thonhauser The influence of dispersion interactions on the hydrogen adsorption properties of expanded graphiteYungok Ihm, Valentino R Cooper, Lujian Peng and James R Morris A DFT-D study of structural and energetic properties of TiO2 modificationsJonas Moellmann, Stephan Ehrlich, Ralf Tonner and Stefan Grimme Spherical-shell model for the van der Waals coefficients between fullerenes and/or nearly spherical nanoclustersJohn P Perdew, Jianmin Tao, Pan Hao, Adrienn Ruzsinszky, Gábor I Csonka and J M Pitarke Dynamical screening of the van der Waals interaction between graphene layersY J Dappe, P G Bolcatto, J Ortega and F Flores Structural evolution of amino acid crystals under stress from a non-empirical density functionalRiccardo Sabatini, Emine Küçükbenli, Brian Kolb, T Thonhauser and Stefano de Gironcoli Physisorption of nucleobases on graphene: a comparative van der Waals studyDuy Le, Abdelkader Kara, Elsebeth Schröder, Per Hyldgaard and Talat S Rahman The role of van der Waals interactions in the adsorption of noble gases on metal surfacesDe-Li Chen, W A Al-Saidi and J Karl Johnson Desorption of n-alkanes from graphene: a van der Waals density functional studyElisa Londero, Emma K Karlson, Marcus Landahl, Dimitri Ostrovskii, Jonatan D Rydberg and Elsebeth Schröder Benchmarking van der Waals density functionals with experimental data

  4. The 12th Edition of the Scientific Days of the National Institute for Infectious Diseases “Prof. Dr. Matei Bals” and the 12th National Infectious Diseases Conference

    Directory of Open Access Journals (Sweden)

    Cristian-Mihail Niculae

    2016-11-01

    Tălăpan A9 Streptococcus pneumoniae meningitis presenting with normal CSF – case presentation Ramona Ștefania Popescu, Luminița Bradu, Dragoș Florea, Adrian Streinu-Cercel A10 Extrapulmonary manifestations of infection with Mycoplasma pneumoniae – study on 24 cases Daniela Anicuta Leca, Elena Bunea, Andra Teodor, Egidia Miftode A11 The molecular diagnosis of severe bacterial sepsis in pediatric population Mădălina Merișescu, Gheorghiță Jugulete, Adrian Streinu-Cercel, Dragoș Florea, Monica Luminos A12 Acute Staphylococcus aureus endocarditis with multiple septic complications in a patient with diabetes mellitus – case presentation Ramona Ștefania Popescu, Anamaria Dobrotă, Adina Ilie, Liliana Lucia Preoțescu A13 Is Streptococcus suis meningitis an under-diagnosed zoonosis? Adriana Hristea, Raluca Jipa, Nicoleta Irimescu, Irina Panait, Eliza Manea, Simona Merisor, Cristian Niculae, Daniela Tălăpan A14 Klebsiella pneumoniae isolated from blood. Antimicrobial resistance – past and present Liana Cătălina Gavriliu, Otilia Elisabeta Benea, Șerban Benea, Alexandru Rafila, Olga Dorobăț, Mona Popoiu A15 Antibiotics resistance in Staphylococcus aureus isolated from blood cultures Livia Dragonu, Augustin Cupşa, Iulian Diaconescu, Irina Niculescu, Lucian Giubelan, Florentina Dumitrescu, Andreea Cristina Stoian, Camelia Guţă, Simona Puiu A16 Predominance of CTX-M enzymes in extended-spectrum β-lactamase-producing Enterobacteriaceae in two hospitals of Quebec City Bunescu Irina, Marilyse Vallée, Ann Huletsky, Dominique K. Boudreau, Ève Bérubé, Richard Giroux, Jean Longtin, Yves Longtin, Michel G. Bergeron A17 Postoperative meningoencephalitis with Acinetobacter baumannii XDR – a therapeutic challenge - Case report Cleo Nicoleta Roșculeț, Dalila-Ana Toma, Catrinel Ciuca, Daniela Tălăpan, Cătălin Apostolescu, Andrei Rogoz, Andrei Stangaciu, Viorica Mitescu, Tudor Vladoiu, Doina Iovănescu A18 Septic arthritis with Burkholderia cepacia