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Sample records for large volume hpge

  1. Characterization of large volume HPGe detectors. Part II: Experimental results

    International Nuclear Information System (INIS)

    Bruyneel, Bart; Reiter, Peter; Pascovici, Gheorghe

    2006-01-01

    Measurements on a 12-fold segmented, n-type, large volume, irregular shaped HPGe detector were performed in order to determine the parameters of anisotropic mobility for electrons and holes as charge carriers created by γ-ray interactions. To characterize the electron mobility the complete outer detector surface was scanned in small steps employing photopeak interactions at 60keV. A precise measurement of the hole drift anisotropy was performed with 356keV γ-rays. The drift velocity anisotropy and crystal geometry cause considerable rise time differences in pulse shapes depending on the position of the spatial charge carrier creation. Pulse shapes of direct and transient signals are reproduced by weighting potential calculations with high precision. The measured angular dependence of rise times is caused by the anisotropic mobility, crystal geometry, changing field strength and space charge effects. Preamplified signals were processed employing digital spectroscopy electronics. Response functions, crosstalk contributions and averaging procedures were taken into account implying novel methods due to the segmentation of the Ge-crystal and digital signal processing electronics

  2. Studies on a pulse shaping system for fast coincidence with very large volume HPGe detectors

    International Nuclear Information System (INIS)

    Bose, S.; Chatterjee, M.B.; Sinha, B.K.; Bhattacharya, R.

    1987-01-01

    A variant of the leading edge timing (LET) has been proposed which compensates the ''walk'' due to risetime spread in very large volume (∝100 cm 3 ) HPGe detectors. The method - shape compensated leading edge timing (SCLET) - can be used over a wide dynamic range of energies with 100% efficiency and has been compared with the LET and ARC methods. A time resolution of 10 ns fwhm and 21 ns fwtm has been obtained with 22 Na gamma rays and two HPGe detectors of 96 and 114 cm 3 volume. This circuit is easy to duplicate and use can be a low cost alternative to commercial circuits in experiments requiring a large number of detectors. (orig.)

  3. HPGe detector shielding adjustment

    International Nuclear Information System (INIS)

    Trnkova, L.; Rulik, P.

    2008-01-01

    Low-level background shielding of HPGe detectors is used mainly for environmental samples with very low content of radionuclides. National Radiation Protection Institute (SURO) in Prague is equipped with 14 HPGe detectors with relative efficiency up to 150%. The detectors are placed in a room built from materials with low content of natural radionuclides and equipped with a double isolation of the floor against radon. Detectors themselves are placed in lead or steel shielding. Steel shielding with one of these detectors with relative efficiency of 100% was chosen to be rebuilt to achieve lower minimum detectable activity (MDA). Additional lead and copper shielding was built up inside the original steel shielding to reduce the volume of the inner space and filled with nitrogen by means of evaporating liquid nitrogen. The additional lead and copper shielding, consequent reduction of the inner volume and supply of evaporated nitrogen, caused a decrease of the background count and accordingly MDA values as well. The effect of nitrogen evaporation on the net areas of peaks belonging to radon daughters is significant. The enhanced shielding adjustment has the biggest influence in low energy range, what can be seen in collected data. MDA values in energy range from 30 keV to 400 keV decreased to 0.65-0.85 of original value, in energy range from 400 keV to 2 MeV they fell to 0.70-0.97 of original value. (authors)

  4. Characterization of segmented large volume, high purity germanium detectors

    Energy Technology Data Exchange (ETDEWEB)

    Bruyneel, B. [Koeln Univ. (Germany). Inst. fuer Kernphysik

    2006-07-01

    {gamma}-ray tracking in future HPGe arrays like AGATA will rely on pulse shape analysis (PSA) of multiple {gamma}-interactions. For this purpose, a simple and fast procedure was developed which enabled the first full characterization of a segmented large volume HPGe detector. An analytical model for the hole mobility in a Ge crystal lattice was developed to describe the hole drift anisotropy with experimental velocity values along the crystal axis as parameters. The new model is based on the drifted Maxwellian hole distribution in Ge. It is verified by reproducing successfully experimental longitudinal hole anisotropy data. A comparison between electron and hole mobility shows large differences for the longitudinal and tangential velocity anisotropy as a function of the electrical field orientation. Measurements on a 12 fold segmented, n-type, large volume, irregular shaped HPGe detector were performed in order to determine the parameters of anisotropic mobility for electrons and holes as charge carriers created by {gamma}-ray interactions. To characterize the electron mobility the complete outer detector surface was scanned in small steps employing photopeak interactions at 60 keV. A precise measurement of the hole drift anisotropy was performed with 356 keV rays. The drift velocity anisotropy and crystal geometry cause considerable rise time differences in pulse shapes depending on the position of the spatial charge carrier creation. Pulse shapes of direct and transient signals are reproduced by weighting potential calculations with high precision. The measured angular dependence of rise times is caused by the anisotropic mobility, crystal geometry, changing field strength and space charge effects. Preamplified signals were processed employing digital spectroscopy electronics. Response functions, crosstalk contributions and averaging procedures were taken into account implying novel methods due to the segmentation of the Ge-crystal and the digital electronics

  5. Characterization of segmented large volume, high purity germanium detectors

    International Nuclear Information System (INIS)

    Bruyneel, B.

    2006-01-01

    γ-ray tracking in future HPGe arrays like AGATA will rely on pulse shape analysis (PSA) of multiple γ-interactions. For this purpose, a simple and fast procedure was developed which enabled the first full characterization of a segmented large volume HPGe detector. An analytical model for the hole mobility in a Ge crystal lattice was developed to describe the hole drift anisotropy with experimental velocity values along the crystal axis as parameters. The new model is based on the drifted Maxwellian hole distribution in Ge. It is verified by reproducing successfully experimental longitudinal hole anisotropy data. A comparison between electron and hole mobility shows large differences for the longitudinal and tangential velocity anisotropy as a function of the electrical field orientation. Measurements on a 12 fold segmented, n-type, large volume, irregular shaped HPGe detector were performed in order to determine the parameters of anisotropic mobility for electrons and holes as charge carriers created by γ-ray interactions. To characterize the electron mobility the complete outer detector surface was scanned in small steps employing photopeak interactions at 60 keV. A precise measurement of the hole drift anisotropy was performed with 356 keV rays. The drift velocity anisotropy and crystal geometry cause considerable rise time differences in pulse shapes depending on the position of the spatial charge carrier creation. Pulse shapes of direct and transient signals are reproduced by weighting potential calculations with high precision. The measured angular dependence of rise times is caused by the anisotropic mobility, crystal geometry, changing field strength and space charge effects. Preamplified signals were processed employing digital spectroscopy electronics. Response functions, crosstalk contributions and averaging procedures were taken into account implying novel methods due to the segmentation of the Ge-crystal and the digital electronics. The results are

  6. Compton imaging with a highly-segmented, position-sensitive HPGe detector

    Energy Technology Data Exchange (ETDEWEB)

    Steinbach, T.; Hirsch, R.; Reiter, P.; Birkenbach, B.; Bruyneel, B.; Eberth, J.; Hess, H.; Lewandowski, L. [Universitaet zu Koeln, Institut fuer Kernphysik, Koeln (Germany); Gernhaeuser, R.; Maier, L.; Schlarb, M.; Weiler, B.; Winkel, M. [Technische Universitaet Muenchen, Physik Department, Garching (Germany)

    2017-02-15

    A Compton camera based on a highly-segmented high-purity germanium (HPGe) detector and a double-sided silicon-strip detector (DSSD) was developed, tested, and put into operation; the origin of γ radiation was determined successfully. The Compton camera is operated in two different modes. Coincidences from Compton-scattered γ-ray events between DSSD and HPGe detector allow for best angular resolution; while the high-efficiency mode takes advantage of the position sensitivity of the highly-segmented HPGe detector. In this mode the setup is sensitive to the whole 4π solid angle. The interaction-point positions in the 36-fold segmented large-volume HPGe detector are determined by pulse-shape analysis (PSA) of all HPGe detector signals. Imaging algorithms were developed for each mode and successfully implemented. The angular resolution sensitively depends on parameters such as geometry, selected multiplicity and interaction-point distances. Best results were obtained taking into account the crosstalk properties, the time alignment of the signals and the distance metric for the PSA for both operation modes. An angular resolution between 13.8 {sup circle} and 19.1 {sup circle}, depending on the minimal interaction-point distance for the high-efficiency mode at an energy of 1275 keV, was achieved. In the coincidence mode, an increased angular resolution of 4.6 {sup circle} was determined for the same γ-ray energy. (orig.)

  7. Large volume cryogenic silicon detectors

    International Nuclear Information System (INIS)

    Braggio, C.; Boscardin, M.; Bressi, G.; Carugno, G.; Corti, D.; Galeazzi, G.; Zorzi, N.

    2009-01-01

    We present preliminary measurements for the development of a large volume silicon detector to detect low energy and low rate energy depositions. The tested detector is a one cm-thick silicon PIN diode with an active volume of 31 cm 3 , cooled to the liquid helium temperature to obtain depletion from thermally-generated free carriers. A thorough study has been done to show that effects of charge trapping during drift disappears at a bias field value of the order of 100V/cm.

  8. Large volume cryogenic silicon detectors

    Energy Technology Data Exchange (ETDEWEB)

    Braggio, C. [Dipartimento di Fisica, Universita di Padova, via Marzolo 8, 35131 Padova (Italy); Boscardin, M. [Fondazione Bruno Kessler (FBK), via Sommarive 18, I-38100 Povo (Italy); Bressi, G. [INFN sez. di Pavia, via Bassi 6, 27100 Pavia (Italy); Carugno, G.; Corti, D. [INFN sez. di Padova, via Marzolo 8, 35131 Padova (Italy); Galeazzi, G. [INFN lab. naz. Legnaro, viale dell' Universita 2, 35020 Legnaro (Italy); Zorzi, N. [Fondazione Bruno Kessler (FBK), via Sommarive 18, I-38100 Povo (Italy)

    2009-12-15

    We present preliminary measurements for the development of a large volume silicon detector to detect low energy and low rate energy depositions. The tested detector is a one cm-thick silicon PIN diode with an active volume of 31 cm{sup 3}, cooled to the liquid helium temperature to obtain depletion from thermally-generated free carriers. A thorough study has been done to show that effects of charge trapping during drift disappears at a bias field value of the order of 100V/cm.

  9. Pulse shape analysis and position determination in segmented HPGe detectors: The AGATA detector library

    Energy Technology Data Exchange (ETDEWEB)

    Bruyneel, B. [Universitaet zu Koeln, Institut fuer Kernphysik, Koeln (Germany); Service de Physique Nucleaire, CEA Saclay, Gif-sur-Yvette (France); Birkenbach, B.; Reiter, P. [Universitaet zu Koeln, Institut fuer Kernphysik, Koeln (Germany)

    2016-03-15

    The AGATA Detector Library (ADL) was developed for the calculation of signals from highly segmented large volume high-purity germanium (HPGe) detectors. ADL basis sets comprise a huge amount of calculated position-dependent detector pulse shapes. A basis set is needed for Pulse Shape Analysis (PSA). By means of PSA the interaction position of a γ -ray inside the active detector volume is determined. Theoretical concepts of the calculations are introduced and cover the relevant aspects of signal formation in HPGe. The approximations and the realization of the computer code with its input parameters are explained in detail. ADL is a versatile and modular computer code; new detectors can be implemented in this library. Measured position resolutions of the AGATA detectors based on ADL are discussed. (orig.)

  10. Large volume axionic Swiss cheese inflation

    Science.gov (United States)

    Misra, Aalok; Shukla, Pramod

    2008-09-01

    Continuing with the ideas of (Section 4 of) [A. Misra, P. Shukla, Moduli stabilization, large-volume dS minimum without anti-D3-branes, (non-)supersymmetric black hole attractors and two-parameter Swiss cheese Calabi Yau's, arXiv: 0707.0105 [hep-th], Nucl. Phys. B, in press], after inclusion of perturbative and non-perturbative α corrections to the Kähler potential and (D1- and D3-) instanton generated superpotential, we show the possibility of slow roll axionic inflation in the large volume limit of Swiss cheese Calabi Yau orientifold compactifications of type IIB string theory. We also include one- and two-loop corrections to the Kähler potential but find the same to be subdominant to the (perturbative and non-perturbative) α corrections. The NS NS axions provide a flat direction for slow roll inflation to proceed from a saddle point to the nearest dS minimum.

  11. Large volume axionic Swiss cheese inflation

    International Nuclear Information System (INIS)

    Misra, Aalok; Shukla, Pramod

    2008-01-01

    Continuing with the ideas of (Section 4 of) [A. Misra, P. Shukla, Moduli stabilization, large-volume dS minimum without anti-D3-branes, (non-)supersymmetric black hole attractors and two-parameter Swiss cheese Calabi-Yau's, (arXiv: 0707.0105 [hep-th]), Nucl. Phys. B, in press], after inclusion of perturbative and non-perturbative α ' corrections to the Kaehler potential and (D1- and D3-) instanton generated superpotential, we show the possibility of slow roll axionic inflation in the large volume limit of Swiss cheese Calabi-Yau orientifold compactifications of type IIB string theory. We also include one- and two-loop corrections to the Kaehler potential but find the same to be subdominant to the (perturbative and non-perturbative) α ' corrections. The NS-NS axions provide a flat direction for slow roll inflation to proceed from a saddle point to the nearest dS minimum

  12. Metrological tests of a 200 L calibration source for HPGE detector systems for assay of radioactive waste drums

    International Nuclear Information System (INIS)

    Boshkova, T.; Mitev, K.

    2016-01-01

    In this work we present test procedures, approval criteria and results from two metrological inspections of a certified large volume "1"5"2Eu source (drum about 200 L) intended for calibration of HPGe gamma assay systems used for activity measurement of radioactive waste drums. The aim of the inspections was to prove the stability of the calibration source during its working life. The large volume source was designed and produced in 2007. It consists of 448 identical sealed radioactive sources (modules) apportioned in 32 transparent plastic tubes which were placed in a wooden matrix which filled the drum. During the inspections the modules were subjected to tests for verification of their certified characteristics. The results show a perfect compliance with the NIST basic guidelines for the properties of a radioactive certified reference material (CRM) and demonstrate the stability of the large volume CRM-drum after 7 years of operation. - Highlights: • Large (200 L) volume drum source designed, produced and certified as CRM in 2007. • Source contains 448 identical sealed radioactive "1"5"2Eu sources (modules). • Two metrological inspections in 2011 and 2014. • No statistically significant changes of the certified characteristics over time. • Stable calibration source for HPGe-gamma radioactive waste assay systems.

  13. Crosstalk properties of 36-fold segmented symmetric hexagonal HPGe detectors

    International Nuclear Information System (INIS)

    Bruyneel, Bart; Reiter, Peter; Wiens, Andreas; Eberth, Juergen; Hess, Herbert; Pascovici, Gheorghe; Warr, Nigel; Weisshaar, Dirk

    2009-01-01

    Crosstalk properties of three 36-fold segmented, symmetric, large volume, HPGe detectors from the AGATA Collaboration were deduced from coincidence measurements performed with digitized segment and core signals after interaction of γ rays with energies of 1.33 MeV. The mean energy values measured by the core signal fluctuate for γ-ray interactions with energy deposited in two segments. A regular pattern is observed depending on the hit segment combinations. The core energy shifts deviate 0.03-0.06% from the average energy calibration. The segment-sum energy is reduced with respect to the core energy as a function of the decoupling capacitance and the segment multiplicity. The deviation of the segment-sum energies from multiplicity two events fluctuates within an interval of less than 0.1% depending on the different segment combinations. The energy shifts caused by crosstalk for the core and segment signals are comparable for all three detectors. A linear electronic model of the detector and preamplifier assembly was developed to evaluate the results. The fold-dependent energy shifts of the segment-sum energies are reproduced. The model yields a constant shift in all segments, proportional to the core signal. The measured crosstalk pattern and its intensity variation in the segments agree well with the calculated values. The regular variation observed in the core energies cannot be directly related to crosstalk and may be caused by other effects like electron trapping.

  14. Metrological tests of a 200 L calibration source for HPGE detector systems for assay of radioactive waste drums.

    Science.gov (United States)

    Boshkova, T; Mitev, K

    2016-03-01

    In this work we present test procedures, approval criteria and results from two metrological inspections of a certified large volume (152)Eu source (drum about 200L) intended for calibration of HPGe gamma assay systems used for activity measurement of radioactive waste drums. The aim of the inspections was to prove the stability of the calibration source during its working life. The large volume source was designed and produced in 2007. It consists of 448 identical sealed radioactive sources (modules) apportioned in 32 transparent plastic tubes which were placed in a wooden matrix which filled the drum. During the inspections the modules were subjected to tests for verification of their certified characteristics. The results show a perfect compliance with the NIST basic guidelines for the properties of a radioactive certified reference material (CRM) and demonstrate the stability of the large volume CRM-drum after 7 years of operation. Copyright © 2015 Elsevier Ltd. All rights reserved.

  15. Measurements and simulation-based optimization of TIGRESS HPGe detector array performance

    International Nuclear Information System (INIS)

    Schumaker, M.A.

    2005-01-01

    TIGRESS is a new γ-ray detector array being developed for installation at the new ISAC-II facility at TRIUMF in Vancouver. When complete, it will consist of twelve large-volume segmented HPGe clover detectors, fitted with segmented Compton suppression shields. The combined operation of prototypes of both a TIGRESS detector and a suppression shield has been tested. Peak-to-total ratios, relative photopeak efficiencies, and energy resolution functions have been determined in order to characterize the performance of TIGRESS. This information was then used to refine a GEANT4 simulation of the full detector array. Using this simulation, methods to overcome the degradation of the photopeak efficiency and peak-to-total response that occurs with high γ-ray multiplicity events were explored. These methods take advantage of the high segmentation of both the HPGe clovers and the suppression shields to suppress or sum detector interactions selectively. For a range of γ-ray energies and multiplicities, optimal analysis methods have been determined, which has resulted in significant gains in the expected performance of TIGRESS. (author)

  16. The parallel volume at large distances

    DEFF Research Database (Denmark)

    Kampf, Jürgen

    In this paper we examine the asymptotic behavior of the parallel volume of planar non-convex bodies as the distance tends to infinity. We show that the difference between the parallel volume of the convex hull of a body and the parallel volume of the body itself tends to . This yields a new proof...... for the fact that a planar body can only have polynomial parallel volume, if it is convex. Extensions to Minkowski spaces and random sets are also discussed....

  17. The parallel volume at large distances

    DEFF Research Database (Denmark)

    Kampf, Jürgen

    In this paper we examine the asymptotic behavior of the parallel volume of planar non-convex bodies as the distance tends to infinity. We show that the difference between the parallel volume of the convex hull of a body and the parallel volume of the body itself tends to 0. This yields a new proof...... for the fact that a planar body can only have polynomial parallel volume, if it is convex. Extensions to Minkowski spaces and random sets are also discussed....

  18. Large volumes and spectroscopy of walking theories

    CERN Document Server

    Del Debbio, L; Patella, A; Pica, C; Rago, A

    2016-01-01

    A detailed investigation of finite size effects is performed for SU(2) gauge theory with two fermions in the adjoint representation, which previous lattice studies have shown to be inside the conformal window. The system is investigated with different spatial and temporal boundary conditions on lattices of various spatial and temporal extensions, for two values of the bare fermion mass representing a {\\em heavy} and {\\em light} fermion regime. Our study shows that the infinite volume limit of masses and decay constants in the mesonic sector is reached only when the mass of the pseudoscalar particle $M_\\mathrm{PS}$ and the spatial lattice size $L$ satisfy the relation $L M_\\mathrm{PS} \\ge 15$. This bound, which is at least a factor of three higher than what observed in QCD, is a likely consequence of the different spectral signatures of the two theories, with the scalar isosinglet ($0^{++}$ glueball) being the lightest particle in our model. In addition to stressing the importance of simulating large lattice s...

  19. Soucreless efficiency calibration for HPGe detector based on medical images

    International Nuclear Information System (INIS)

    Chen Chaobin; She Ruogu; Xiao Gang; Zuo Li

    2012-01-01

    Digital phantom of patient and region of interest (supposed to be filled with isotropy volume source) are built from medical CT images. They are used to calculate the detection efficiency of HPGe detectors located outside of human body by sourceless calibration method based on a fast integral technique and MCNP code respectively, and the results from two codes are in good accord besides a max difference about 5% at intermediate energy region. The software produced in this work are in better behavior than Monte Carlo code not only in time consume but also in complexity of problem to solve. (authors)

  20. Volume independence in large Nc QCD-like gauge theories

    International Nuclear Information System (INIS)

    Kovtun, Pavel; Uensal, Mithat; Yaffe, Laurence G.

    2007-01-01

    Volume independence in large N c gauge theories may be viewed as a generalized orbifold equivalence. The reduction to zero volume (or Eguchi-Kawai reduction) is a special case of this equivalence. So is temperature independence in confining phases. A natural generalization concerns volume independence in 'theory space' of quiver gauge theories. In pure Yang-Mills theory, the failure of volume independence for sufficiently small volumes (at weak coupling) due to spontaneous breaking of center symmetry, together with its validity above a critical size, nicely illustrate the symmetry realization conditions which are both necessary and sufficient for large N c orbifold equivalence. The existence of a minimal size below which volume independence fails also applies to Yang-Mills theory with antisymmetric representation fermions [QCD(AS)]. However, in Yang-Mills theory with adjoint representation fermions [QCD(Adj)], endowed with periodic boundary conditions, volume independence remains valid down to arbitrarily small size. In sufficiently large volumes, QCD(Adj) and QCD(AS) have a large N c ''orientifold'' equivalence, provided charge conjugation symmetry is unbroken in the latter theory. Therefore, via a combined orbifold-orientifold mapping, a well-defined large N c equivalence exists between QCD(AS) in large, or infinite, volume and QCD(Adj) in arbitrarily small volume. Since asymptotically free gauge theories, such as QCD(Adj), are much easier to study (analytically or numerically) in small volume, this equivalence should allow greater understanding of large N c QCD in infinite volume

  1. Effects of uncertainty in model predictions of individual tree volume on large area volume estimates

    Science.gov (United States)

    Ronald E. McRoberts; James A. Westfall

    2014-01-01

    Forest inventory estimates of tree volume for large areas are typically calculated by adding model predictions of volumes for individual trees. However, the uncertainty in the model predictions is generally ignored with the result that the precision of the large area volume estimates is overestimated. The primary study objective was to estimate the effects of model...

  2. Direct determination of the hit locations from experimental HPGe pulses

    Energy Technology Data Exchange (ETDEWEB)

    Désesquelles, P., E-mail: Pierre.Desesquelles@in2p3.fr [Univ. Paris-Sud, CSNSM CNRS/IN2P3, 15 rue G. Clémenceau, 91405 Orsay (France); Boston, A.J.; Boston, H.C.; Cresswell, J.R.; Dimmock, M.R. [Oliver Lodge Laboratory, The University of Liverpool, Oxford Street, Liverpool L69 7ZE (United Kingdom); Lazarus, I.H. [STFC Daresbury Laboratory, Daresbury, Warrington WA4 4AD (United Kingdom); Ljungvall, J. [Univ. Paris-Sud, CSNSM CNRS/IN2P3, 15 rue G. Clémenceau, 91405 Orsay (France); Nelson, L. [Oliver Lodge Laboratory, The University of Liverpool, Oxford Street, Liverpool L69 7ZE (United Kingdom); Nga, D.-T. [Univ. Paris-Sud, CSNSM CNRS/IN2P3, 15 rue G. Clémenceau, 91405 Orsay (France); Nolan, P.J.; Rigby, S.V. [Oliver Lodge Laboratory, The University of Liverpool, Oxford Street, Liverpool L69 7ZE (United Kingdom); Simpson, J. [STFC Daresbury Laboratory, Daresbury, Warrington WA4 4AD (United Kingdom); Van-Oanh, N.-T. [Univ. Paris-Sud, LCP UMR8000 CNRS, 15 rue G. Clémenceau, 91405 Orsay (France)

    2013-11-21

    The gamma-tracking technique optimises the determination of the energy and emission angle of gamma-rays detected by modern segmented HPGe detectors. This entails the determination, using the delivered pulse shapes, of the interaction points of the gamma-ray within the crystal. The direct method presented here allows the localisation of the hits using only a large sample of pulses detected in the actual operating conditions. No external crystal scanning system or pulse shape simulation code is needed. In order to validate this method, it is applied to sets of pulses obtained using the University of Liverpool scanning system. The hit locations are determined by the method with good precision.

  3. Preface to the volume Large Rivers

    Science.gov (United States)

    Latrubesse, Edgardo M.; Abad, Jorge D.

    2018-02-01

    The study and knowledge of the geomorphology of large rivers increased significantly during the last years and the factors that triggered these advances are multiple. On one hand, modern technologies became more accessible and their disseminated usage allowed the collection of data from large rivers as never seen before. The generalized use of high tech data collection with geophysics equipment such as acoustic Doppler current profilers-ADCPs, multibeam echosounders, plus the availability of geospatial and computational tools for morphodynamics, hydrological and hydrosedimentological modeling, have accelerated the scientific production on the geomorphology of large rivers at a global scale. Despite the advances, there is yet a lot of work ahead. Good parts of the large rivers are in the tropics and many are still unexplored. The tropics also hold crucial fluvial basins that concentrate good part of the gross domestic product of large countries like the Parana River in Argentina and Brazil, the Ganges-Brahmaputra in India, the Indus River in Pakistan, and the Mekong River in several countries of South East Asia. The environmental importance of tropical rivers is also outstanding. They hold the highest biodiversity of fluvial fauna and alluvial vegetation and many of them, particularly those in Southeast Asia, are among the most hazardous systems for floods in the entire world. Tropical rivers draining mountain chains such as the Himalaya, the Andes and insular Southeast Asia are also among the most heavily sediment loaded rivers and play a key role in both the storage of sediment at continental scale and the transference of sediments from the continent to the Ocean at planetary scale (Andermann et al., 2012; Latrubesse and Restrepo, 2014; Milliman and Syvitski, 1992; Milliman and Farsnworth, 2011; Sinha and Friend, 1994).

  4. Method applied for the HPGe detector characterization

    International Nuclear Information System (INIS)

    Guillot, Nicolas; Monestier, Mathieu; Saurel, Nicolas

    2013-06-01

    Gamma ray spectrometry is a passive non destructive assay most commonly used to identify and quantify the radionuclides present in the complex huge objects such as nuclear waste packages. The treatment of spectra from the measurement of nuclear waste is performed in two steps: the first step is to extract the raw data from the spectra (energies and net photoelectric absorption peaks areas) and the second step is to determine the detection efficiency of the measured scene. The establishment by numerical modeling of the detection efficiency of the measured scene requires numerical modeling of both the measuring device (in this case a hyper pure germanium detector HPGe) and numerical modeling of the measured object. Numerical detector modeling is also called diode characterization, and has a spatial response equivalent to these of the real HPGe detector. This characterization is essential for the quantification of complex and non reproducible huge objects for which the detection efficiency can not be determined empirically. The Nuclear Measurement and Valuation Laboratory (LMNE) at the Atomic Energy Commission Valduc (CEA Valduc) has developed a new methodology for characterizing the HPGe detector. It has been tested experimentally with a real diode present in the laboratory (P-type planar detector). The characterization obtained with this methodology is similar to these of a real HPGe detector with an uncertainty approaching 5 percents. It is valid for a distance ranging from 10 cm to 150 cm, an angle ranging from 0 to 90 degrees and energy range from 53 keV to 1112 keV. The energy range is obtained with a source of Barium-133 and a source of Europium-152. The continuity of the detection efficiency curve is checked between the two sources with an uncertainty less than 2 percents. In addition, this methodology can be extrapolated to any type of detector crystal geometry (planar). (authors)

  5. New large volume Calabi-Yau threefolds

    Science.gov (United States)

    Altman, Ross; He, Yang-Hui; Jejjala, Vishnu; Nelson, Brent D.

    2018-02-01

    In previous work, we have commenced the task of unpacking the 473 800 776 reflexive polyhedra by Kreuzer and Skarke into a database of Calabi-Yau threefolds [R. Altman et al. J. High Energy Phys. 02 (2015) 158., 10.1007/JHEP02(2015)158] (see www.rossealtman.com). In this paper, following a pedagogical introduction, we present a new algorithm to isolate Swiss cheese solutions characterized by "holes," or small 4-cycles, descending from the toric divisors inherent to the original four dimensional reflexive polyhedra. Implementing these methods, we find 2268 explicit Swiss cheese manifolds, over half of which have h1 ,1=6 . Many of our solutions have multiple large cycles. Such Swiss cheese geometries facilitate moduli stabilization in string compactifications and provide flat directions for cosmological inflation.

  6. Large volumes and spectroscopy of walking theories

    DEFF Research Database (Denmark)

    Del Debbio, L.; Lucini, B.; Patella, A.

    2016-01-01

    A detailed investigation of finite-size effects is performed for SU(2) gauge theory with two fermions in the adjoint representation, which previous lattice studies have shown to be inside the conformal window. The system is investigated with different spatial and temporal boundary conditions...... and the spatial lattice size L satisfy the relation LMPS≥15. This bound, which is at least a factor of three higher than what is observed in QCD, is a likely consequence of the different spectral signatures of the two theories, with the scalar isosinglet (0++ glueball) being the lightest particle in our model....... In addition to stressing the importance of simulating large lattice sizes, our analysis emphasizes the need to understand quantitatively the full spectrum of the theory rather than just the spectrum in the mesonic isotriplet sector. While for the lightest fermion measuring masses from gluonic operators proves...

  7. Study of Efficiency Calibrations of HPGe Detectors for Radioactivity Measurements of Environmental Samples

    International Nuclear Information System (INIS)

    Harb, S.; Salahel Din, K.; Abbady, A.

    2009-01-01

    In this paper, we describe a method of calibrating of efficiency of a HPGe gamma-ray spectrometry of bulk environmental samples (Tea, crops, water, and soil) is a significant part of the environmental radioactivity measurements. Here we will discuss the full energy peak efficiency (FEPE) of three HPGe detectors it as a consequence, it is essential that the efficiency is determined for each set-up employed. Besides to take full advantage at gamma-ray spectrometry, a set of efficiency at several energies which covers the wide the range in energy, the large the number of radionuclides whose concentration can be determined to measure the main natural gamma-ray emitters, the efficiency should be known at least from 46.54 keV ( 210 Pb) to 1836 keV ( 88 Y). Radioactive sources were prepared from two different standards, a first mixed standard QC Y 40 containing 210 Pb, 241 Am, 109 Cd, and Co 57 , and the second QC Y 48 containing 241 Am, 109 Cd, 57 Co, 139 Ce, 113 Sn, 85 Sr, 137 Cs, 88 Y, and 60 Co is necessary in order to calculate the activity of the different radionuclides contained in a sample. In this work, we will study the efficiency calibration as a function of different parameters as:- Energy of gamma ray from 46.54 keV ( 210 Pb) to 1836 keV ( 88 Y), three different detectors A, B, and C, geometry of containers (point source, marinelli beaker, and cylindrical bottle 1 L), height of standard soil samples in bottle 250 ml, and density of standard environmental samples. These standard environmental sample must be measured before added standard solution because we will use the same environmental samples in order to consider the self absorption especially and composition in the case of volume samples.

  8. Volume measurement study for large scale input accountancy tank

    International Nuclear Information System (INIS)

    Uchikoshi, Seiji; Watanabe, Yuichi; Tsujino, Takeshi

    1999-01-01

    Large Scale Tank Calibration (LASTAC) facility, including an experimental tank which has the same volume and structure as the input accountancy tank of Rokkasho Reprocessing Plant (RRP) was constructed in Nuclear Material Control Center of Japan. Demonstration experiments have been carried out to evaluate a precision of solution volume measurement and to establish the procedure of highly accurate pressure measurement for a large scale tank with dip-tube bubbler probe system to be applied to the input accountancy tank of RRP. Solution volume in a tank is determined from substitution the solution level for the calibration function obtained in advance, which express a relation between the solution level and its volume in the tank. Therefore, precise solution volume measurement needs a precise calibration function that is determined carefully. The LASTAC calibration experiments using pure water showed good result in reproducibility. (J.P.N.)

  9. Novel HPGe Probe solution for Harsh Environments

    Energy Technology Data Exchange (ETDEWEB)

    Clauss, J.; Pirard, B.; Menaa, N.; Quirin, P.; Flamanc, J.; Marian, V.; Lampert, M.O. [CANBERRA France, Parc des Tanneries, 1, chemin de la roseraie, 67380 Lingolsheim (France)

    2015-07-01

    In situ measurement is a privileged way of monitoring radioactive contamination compared to analyzing samples in a distant, specialized laboratory. Scintillators based spectrometers offer small footprints and are easy to easy to use, however they do not provide an accurate nuclide identification capability and activities measurement because notably of their limited energy resolution, for instance when low minimum detectable activity (MDA) are required, or in complex mixture of sources. On the other hand, High Purity Germanium (HPGe) detectors provide unmatched nuclide identification capability with the lowest MDA but they are not always of practical use on the field because the crystal needs to be cooled down to liquid nitrogen temperature, increasing the overall weight, bulkiness and complexity of the measurement. This paper presents the configuration and performance of a novel turnkey and compact HPGe solution developed by Canberra for radionuclide identification under harsh environments. Radio-contaminations surveys now can be undertaken outdoor under various weather conditions, in contaminated areas, underground or underwater locations (including under sea water), with fast on site deployment. The spectrometer is also designed in a small diameter tubular shape to offer minimal footprint for an operation in narrow and confined spaces. Besides, this innovative design does not mitigate the performances nor the reliability experienced with standard laboratory-grade HPGe spectrometers. This achievement relies on advanced technologies such as the encapsulation of the crystal in ultra-high vacuum (UHV) which provides higher robustness and does not requires thermal cycles faced with regular HPGe equipment. It also relies on a low vibration, low consumption electrical cooler so that no liquid nitrogen is being used. The detector is connected to a state-of-the-art digital spectroscopy suite embedded in an autonomous acquisition station monitoring the cryo-cooler and

  10. Higgs, moduli problem, baryogenesis and large volume compactifications

    International Nuclear Information System (INIS)

    Higaki, Tetsutaro; Takahashi, Fuminobu

    2012-07-01

    We consider the cosmological moduli problem in the context of high-scale supersymmetry breaking suggested by the recent discovery of the standard-model like Higgs boson. In order to solve the notorious moduli-induced gravitino problem, we focus on the LARGE volume scenario, in which the modulus decay into gravitinos can be kinematically forbidden. We then consider the Affleck-Dine mechanism with or without an enhanced coupling with the inflaton, taking account of possible Q-ball formation. We show that the baryon asymmetry of the present Universe can be generated by the Affleck-Dine mechanism in LARGE volume scenario, solving the moduli and gravitino problems.

  11. Higgs, moduli problem, baryogenesis and large volume compactifications

    Energy Technology Data Exchange (ETDEWEB)

    Higaki, Tetsutaro [RIKEN Nishina Center, Saitama (Japan). Mathematical Physics Lab.; Kamada, Kohei [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Takahashi, Fuminobu [Tohoku Univ., Sendai (Japan). Dept. of Physics

    2012-07-15

    We consider the cosmological moduli problem in the context of high-scale supersymmetry breaking suggested by the recent discovery of the standard-model like Higgs boson. In order to solve the notorious moduli-induced gravitino problem, we focus on the LARGE volume scenario, in which the modulus decay into gravitinos can be kinematically forbidden. We then consider the Affleck-Dine mechanism with or without an enhanced coupling with the inflaton, taking account of possible Q-ball formation. We show that the baryon asymmetry of the present Universe can be generated by the Affleck-Dine mechanism in LARGE volume scenario, solving the moduli and gravitino problems.

  12. Extrapolated HPGe efficiency estimates based on a single calibration measurement

    International Nuclear Information System (INIS)

    Winn, W.G.

    1994-01-01

    Gamma spectroscopists often must analyze samples with geometries for which their detectors are not calibrated. The effort to experimentally recalibrate a detector for a new geometry can be quite time consuming, causing delay in reporting useful results. Such concerns have motivated development of a method for extrapolating HPGe efficiency estimates from an existing single measured efficiency. Overall, the method provides useful preliminary results for analyses that do not require exceptional accuracy, while reliably bracketing the credible range. The estimated efficiency element-of for a uniform sample in a geometry with volume V is extrapolated from the measured element-of 0 of the base sample of volume V 0 . Assuming all samples are centered atop the detector for maximum efficiency, element-of decreases monotonically as V increases about V 0 , and vice versa. Extrapolation of high and low efficiency estimates element-of h and element-of L provides an average estimate of element-of = 1/2 [element-of h + element-of L ] ± 1/2 [element-of h - element-of L ] (general) where an uncertainty D element-of = 1/2 (element-of h - element-of L ] brackets limits for a maximum possible error. The element-of h and element-of L both diverge from element-of 0 as V deviates from V 0 , causing D element-of to increase accordingly. The above concepts guided development of both conservative and refined estimates for element-of

  13. Crosstalk corrections for improved energy resolution with highly segmented HPGe-detectors

    International Nuclear Information System (INIS)

    Bruyneel, Bart; Reiter, Peter; Wiens, Andreas; Eberth, Juergen; Hess, Herbert; Pascovici, Gheorghe; Warr, Nigel; Aydin, Sezgin; Bazzacco, Dino; Recchia, Francesco

    2009-01-01

    Crosstalk effects of 36-fold segmented, large volume AGATA HPGe detectors cause shifts in the γ-ray energy measured by the inner core and outer segments as function of segment multiplicity. The positions of the segment sum energy peaks vary approximately linearly with increasing segment multiplicity. The resolution of these peaks deteriorates also linearly as a function of segment multiplicity. Based on single event treatment, two methods were developed in the AGATA Collaboration to correct for the crosstalk induced effects by employing a linear transformation. The matrix elements are deduced from coincidence measurements of γ-rays of various energies as recorded with digital electronics. A very efficient way to determine the matrix elements is obtained by measuring the base line shifts of untriggered segments using γ-ray detection events in which energy is deposited in a single segment. A second approach is based on measuring segment energy values for γ-ray interaction events in which energy is deposited in only two segments. After performing crosstalk corrections, the investigated detector shows a good fit between the core energy and the segment sum energy at all multiplicities and an improved energy resolution of the segment sum energy peaks. The corrected core energy resolution equals the segment sum energy resolution which is superior at all folds compared to the individual uncorrected energy resolutions. This is achieved by combining the two independent energy measurements with the core contact on the one hand and the segment contacts on the other hand.

  14. Pulse shape analysis optimization with segmented HPGe-detectors

    Energy Technology Data Exchange (ETDEWEB)

    Lewandowski, Lars; Birkenbach, Benedikt; Reiter, Peter [Institute for Nuclear Physics, University of Cologne (Germany); Bruyneel, Bart [CEA, Saclay (France); Collaboration: AGATA-Collaboration

    2014-07-01

    Measurements with the position sensitive, highly segmented AGATA HPGe detectors rely on the gamma-ray-tracking GRT technique which allows to determine the interaction point of the individual gamma-rays hitting the detector. GRT is based on a pulse shape analysis PSA of the preamplifier signals from the 36 segments and the central electrode of the detector. The achieved performance and position resolution of the AGATA detector is well within the specifications. However, an unexpected inhomogeneous distribution of interaction points inside the detector volume is observed as a result of the PSA even when the measurement is performed with an isotropically radiating gamma ray source. The clustering of interaction points motivated a study in order to optimize the PSA algorithm or its ingredients. Position resolution results were investigated by including contributions from differential crosstalk of the detector electronics, an improved preamplifier response function and a new time alignment. Moreover the spatial distribution is quantified by employing different χ{sup 2}-minimization procedures.

  15. Absolute efficiency calibration of HPGe detector by simulation method

    International Nuclear Information System (INIS)

    Narayani, K.; Pant, Amar D.; Verma, Amit K.; Bhosale, N.A.; Anilkumar, S.

    2018-01-01

    High resolution gamma ray spectrometry by HPGe detectors is a powerful radio analytical technique for estimation of activity of various radionuclides. In the present work absolute efficiency calibration of the HPGe detector was carried out using Monte Carlo simulation technique and results are compared with those obtained by experiment using standard radionuclides of 152 Eu and 133 Ba. The coincidence summing correction factors for the measurement of these nuclides were also calculated

  16. Coupling of RF antennas to large volume helicon plasma

    Directory of Open Access Journals (Sweden)

    Lei Chang

    2018-04-01

    Full Text Available Large volume helicon plasma sources are of particular interest for large scale semiconductor processing, high power plasma propulsion and recently plasma-material interaction under fusion conditions. This work is devoted to studying the coupling of four typical RF antennas to helicon plasma with infinite length and diameter of 0.5 m, and exploring its frequency dependence in the range of 13.56-70 MHz for coupling optimization. It is found that loop antenna is more efficient than half helix, Boswell and Nagoya III antennas for power absorption; radially parabolic density profile overwhelms Gaussian density profile in terms of antenna coupling for low-density plasma, but the superiority reverses for high-density plasma. Increasing the driving frequency results in power absorption more near plasma edge, but the overall power absorption increases with frequency. Perpendicular stream plots of wave magnetic field, wave electric field and perturbed current are also presented. This work can serve as an important reference for the experimental design of large volume helicon plasma source with high RF power.

  17. A digital gain stabilizer for large volume organic scintillation detectors

    International Nuclear Information System (INIS)

    Braunsfurth, J.; Geske, K.

    1976-01-01

    A digital gain stabilizer is described, optimized for use with photomultipliers mounted on large volume organic scintillators, or other radiation detectors, which exhibit no prominent peaks in their amplitude spectra. As applications of this kind usually involve many phototubes or detectors, circuit simplicity, production reproduceability, and the possibility of computer controlled operation were major design criteria. Two versions were built, the first one using standard TTL-SSI and MSI circuitry, the second one - to reduce power requirements - using a mixture of TTL- and CMOS-LSI circuits. (Auth.)

  18. Removal of rare gases from large volume airstreams

    International Nuclear Information System (INIS)

    Hopke, P.K.; Leong, K.H.; Stukel, J.J.; Lewis, C.; Jebackumar, R.; Illinois Univ., Urbana; Illinois Univ., Urbana

    1986-01-01

    The cost-effective removal of low levels of rare gases and particularly radon from large volume air flows is a difficult problem. The use of various scrubbing systems using non-conventional fluids has been studied. The parameters for both a packed tower absorber and a gas scrubber have been calculated for a system using perfluorobenzene as the fluid. Based on these parameters, a packed bed tower of conventional proportions is feasible for the removal of >95% of 37 Bq/m 3 of radon from a flow of 4.7 m 3 /second. (author)

  19. Naturally light hidden photons in LARGE volume string compactifications

    International Nuclear Information System (INIS)

    Goodsell, M.; Jaeckel, J.; Redondo, J.; Ringwald, A.

    2009-09-01

    Extra ''hidden'' U(1) gauge factors are a generic feature of string theory that is of particular phenomenological interest. They can kinetically mix with the Standard Model photon and are thereby accessible to a wide variety of astrophysical and cosmological observations and laboratory experiments. In this paper we investigate the masses and the kinetic mixing of hidden U(1)s in LARGE volume compactifications of string theory. We find that in these scenarios the hidden photons can be naturally light and that their kinetic mixing with the ordinary electromagnetic photon can be of a size interesting for near future experiments and observations. (orig.)

  20. Large volume syringe pump extruder for desktop 3D printers

    Directory of Open Access Journals (Sweden)

    Kira Pusch

    2018-04-01

    Full Text Available Syringe pump extruders are required for a wide range of 3D printing applications, including bioprinting, embedded printing, and food printing. However, the mass of the syringe becomes a major challenge for most printing platforms, requiring compromises in speed, resolution and/or volume. To address these issues, we have designed a syringe pump large volume extruder (LVE that is compatible with low-cost, open source 3D printers, and herein demonstrate its performance on a PrintrBot Simple Metal. Key aspects of the LVE include: (1 it is open source and compatible with open source hardware and software, making it inexpensive and widely accessible to the 3D printing community, (2 it utilizes a standard 60 mL syringe as its ink reservoir, effectively increasing print volume of the average bioprinter, (3 it is capable of retraction and high speed movements, and (4 it can print fluids using nozzle diameters as small as 100 μm, enabling the printing of complex shapes/objects when used in conjunction with the freeform reversible embedding of suspended hydrogels (FRESH 3D printing method. Printing performance of the LVE is demonstrated by utilizing alginate as a model biomaterial ink to fabricate parametric CAD models and standard calibration objects. Keywords: Additive manufacturing, 3D bioprinting, Embedded printing, FRESH, Soft materials extrusion

  1. Characterization of HPGe detectors using Computed Tomography

    Energy Technology Data Exchange (ETDEWEB)

    Hedman, A., E-mail: Angelica.Hedman@foi.se [Swedish Defence Research Agency, Division of CBRN Defence and Security, SE-90182 Umeå (Sweden); Umeå University, Department of Radiation Sciences, Radiation Physics, SE-90187 Umeå (Sweden); Bahar Gogani, J.; Granström, M. [Swedish Defence Research Agency, Division of CBRN Defence and Security, SE-90182 Umeå (Sweden); Johansson, L.; Andersson, J.S. [Umeå University, Department of Radiation Sciences, Radiation Physics, SE-90187 Umeå (Sweden); Ramebäck, H. [Swedish Defence Research Agency, Division of CBRN Defence and Security, SE-90182 Umeå (Sweden); Chalmers University of Technology, Department of Chemical and Biological Engineering, Nuclear Chemistry, SE-41296 Göteborg (Sweden)

    2015-06-11

    Computed Tomography (CT) high-resolution imaging have been used to investigate if there is a significant change in the crystal-to-window distance, i.e. the air gap thickness, in a small n-type detector cooled to 77 K, and in a medium sized p-type HPGe detector when cooled to 100 K. The findings were compared to detector dimension data made available by the manufacturer. The air gap thickness increased by (0.38±0.07) mm for the n-type detector and by (0.40±0.15) mm for the p-type detector when the detectors were cooled to 77 resp. 100 K compared to at room temperature. Monte Carlo calculations indicate that these differences have a significant impact on the efficiency in close geometries (<5 cm). In the energy range of 40–700 keV with a source placed directly on endcap, the change in detector efficiency with temperature is 1.9–2.9% for the n-type detector and 0.3–2.1% for the p-type detector. The measured air gap thickness when cooling the detector was 1.1 mm thicker than manufacturer data for the n-type detector and 0.2 mm thicker for the p-type detector. In the energy range of 40–700 keV and with a source on endcap, this result in a change in detector efficiency of 5.2–7.1% for the n-type detector and 0.2–1.0% for the p-type detector, i.e. the detector efficiency is overestimated using data available by the manufacturer.

  2. APPHi: Automated Photometry Pipeline for High Cadence Large Volume Data

    Science.gov (United States)

    Sánchez, E.; Castro, J.; Silva, J.; Hernández, J.; Reyes, M.; Hernández, B.; Alvarez, F.; García T.

    2018-04-01

    APPHi (Automated Photometry Pipeline) carries out aperture and differential photometry of TAOS-II project data. It is computationally efficient and can be used also with other astronomical wide-field image data. APPHi works with large volumes of data and handles both FITS and HDF5 formats. Due the large number of stars that the software has to handle in an enormous number of frames, it is optimized to automatically find the best value for parameters to carry out the photometry, such as mask size for aperture, size of window for extraction of a single star, and the number of counts for the threshold for detecting a faint star. Although intended to work with TAOS-II data, APPHi can analyze any set of astronomical images and is a robust and versatile tool to performing stellar aperture and differential photometry.

  3. Effect of large volume paracentesis on plasma volume--a cause of hypovolemia

    International Nuclear Information System (INIS)

    Kao, H.W.; Rakov, N.E.; Savage, E.; Reynolds, T.B.

    1985-01-01

    Large volume paracentesis, while effectively relieving symptoms in patients with tense ascites, has been generally avoided due to reports of complications attributed to an acute reduction in intravascular volume. Measurements of plasma volume in these subjects have been by indirect methods and have not uniformly confirmed hypovolemia. We have prospectively evaluated 18 patients (20 paracenteses) with tense ascites and peripheral edema due to chronic liver disease undergoing 5 liter paracentesis for relief of symptoms. Plasma volume pre- and postparacentesis was assessed by a 125 I-labeled human serum albumin dilution technique as well as by the change in hematocrit and postural blood pressure difference. No significant change in serum sodium, urea nitrogen, hematocrit or postural systolic blood pressure difference was noted at 24 or 48 hr after paracentesis. Serum creatinine at 24 hr after paracentesis was unchanged but a small but statistically significant increase in serum creatinine was noted at 48 hr postparacentesis. Plasma volume changed -2.7% (n = 6, not statistically significant) during the first 24 hr and -2.8% (n = 12, not statistically significant) during the 0- to 48-hr period. No complications from paracentesis were noted. These results suggest that 5 liter paracentesis for relief of symptoms is safe in patients with tense ascites and peripheral edema from chronic liver disease

  4. Adsorption of transuranic elements from large volume sea water

    International Nuclear Information System (INIS)

    Holm, E.; Ballestra, S.

    1976-01-01

    Some years ago a sampler for concentrating radionuclides from large volumes of sea water was developed by Silker et al. of the Battelle Northwest Laboratories. They used pure A1 2 O 3 as the adsorbent. The device has been applied successfully to the determination of 238 Pu and 239 Pu in several sea water samples. Our experience on the application of an identical system for the determination of transuranics in Mediterranean sea water was not quite as satisfactory as we had hoped. The chemistry involved in leaching up to 1 kg Al 2 O 3 . with acid, followed by removal of dissolved aluminium from the transuranic fraction, is rather tedious and time-consuming for routine use. The adsorption efficiency of transuranics, checked by dual-bed adsorption did not give consistent results. However, since the principle of the device is attractive enough for handling large volume water samples, it was felt that it was worthwhile to test other types of adsorbents which are easier to handle than Al 2 O 3 . For this purpose, chitosan and manganese dioxide were chosen and series of experiments were conducted in order to examine the suitability of these materials as an adsorbent in the system

  5. High precision efficiency calibration of a HPGe detector

    International Nuclear Information System (INIS)

    Nica, N.; Hardy, J.C.; Iacob, V.E.; Helmer, R.G.

    2003-01-01

    Many experiments involving measurements of γ rays require a very precise efficiency calibration. Since γ-ray detection and identification also requires good energy resolution, the most commonly used detectors are of the coaxial HPGe type. We have calibrated our 70% HPGe to ∼ 0.2% precision, motivated by the measurement of precise branching ratios (BR) in superallowed 0 + → 0 + β decays. These BRs are essential ingredients in extracting ft-values needed to test the Standard Model via the unitarity of the Cabibbo-Kobayashi-Maskawa matrix, a test that it currently fails by more than two standard deviations. To achieve the required high precision in our efficiency calibration, we measured 17 radioactive sources at a source-detector distance of 15 cm. Some of these were commercial 'standard' sources but we achieved the highest relative precision with 'home-made' sources selected because they have simple decay schemes with negligible side feeding, thus providing exactly matched γ-ray intensities. These latter sources were produced by us at Texas A and M by n-activation or by nuclear reactions. Another critical source among the 17 was a 60 Co source produced by Physikalisch-Technische Bundesanstalt, Braunschweig, Germany: its absolute activity was quoted to better than 0.06%. We used it to establish our absolute efficiency, while all the other sources were used to determine relative efficiencies, extending our calibration over a large energy range (40-3500 keV). Efficiencies were also determined with Monte Carlo calculations performed with the CYLTRAN code. The physical parameters of the Ge crystal were independently determined and only two (unmeasurable) dead-layers were adjusted, within physically reasonable limits, to achieve precise absolute agreement with our measured efficiencies. The combination of measured efficiencies at more than 60 individual energies and Monte Carlo calculations to interpolate between them allows us to quote the efficiency of our

  6. Doping the 1 kton Large Volume Detector with Gd

    Energy Technology Data Exchange (ETDEWEB)

    Bruno, Gianmarco [University of L' Aquila, Via Vetoio snc, 67100 Coppito (AQ) Italy (Italy); Fulgione, Walter; Porta, Amanda [Istituto di Fisica dello Spazio Interplanetario, INAF, Corso Fiume 4, Torino (Italy); Machado, Ana Amelia Bergamini [Laboratori Nazionali del Gran Sasso, INFN, s.s. 17bis Km 18-10, Assergi (AQ) (Italy); Mal' gin, Alexei [Institute for Nuclear Research, Russian Academy of Sciences, pr. Shestidesyatiletiya Oktyabrya 7a, Moscow, 117312 (Russian Federation); Molinario, Andrea; Vigorito, Carlo, E-mail: bruno@to.infn.it, E-mail: fulgione@to.infn.it, E-mail: ana.machado@lngs.infn.it, E-mail: malgin@lngs.infn.it, E-mail: amolinar@to.infn.it, E-mail: Amanda.Porta@subatech.in2p3.fr, E-mail: vigorito@to.infn.it [INFN, Via Pietro Giuria 1, Torino (Italy)

    2011-06-01

    The Large Volume Detector (LVD) in the INFN Gran Sasso National Laboratory (LNGS), Italy, is a ν observatory which has been monitoring the Galaxy since June 1992 to study neutrinos from core collapse supernovae. The experiment in the present configuration is made by 840 scintillator detectors, for a total active mass of 1000 tons. The detector sensitivity to neutrino bursts due to a core collapse supernova has been already discussed in term of maximum detectable distance. In this paper we evaluate the improvements that LVD could obtain if all its active scintillator mass was doped with a small amount (0.14% in weight) of Gadolinium. We simulated neutron captures following ν-bar {sub e} inverse beta decay reactions in one LVD counter (1.2 ton) with Gd doped liquid scintillator obtaining an efficiency for the detection of this process of η{sub n}|{sub Gd} = 80% and a mean capture time τ = 25μs, in good agreement with the results obtained by the measures. This implies a gain of a factor ∼ 20 in the signal to noise ratio for neutron capture detection with respect to the undoped liquid scintillator. We discuss how the captures of neutrons from rock radioactivity on Gd modify the background conditions of the detector and we calculate the curves expressing the sensitivity to a ν-bar {sub e} burst from core collapse supernovae depending on the distance of the collapsing star. It results that doping the 1 kton Large Volume Detector with Gd would assure a 90% detection efficiency at the distance of the Large Magellanic Cloud (50 kpc), an achievement which is equivalent to that obtained by doubling the number of counters in LVD.

  7. Doping the 1 kton Large Volume Detector with Gd

    International Nuclear Information System (INIS)

    Bruno, Gianmarco; Fulgione, Walter; Porta, Amanda; Machado, Ana Amelia Bergamini; Mal'gin, Alexei; Molinario, Andrea; Vigorito, Carlo

    2011-01-01

    The Large Volume Detector (LVD) in the INFN Gran Sasso National Laboratory (LNGS), Italy, is a ν observatory which has been monitoring the Galaxy since June 1992 to study neutrinos from core collapse supernovae. The experiment in the present configuration is made by 840 scintillator detectors, for a total active mass of 1000 tons. The detector sensitivity to neutrino bursts due to a core collapse supernova has been already discussed in term of maximum detectable distance. In this paper we evaluate the improvements that LVD could obtain if all its active scintillator mass was doped with a small amount (0.14% in weight) of Gadolinium. We simulated neutron captures following ν-bar e inverse beta decay reactions in one LVD counter (1.2 ton) with Gd doped liquid scintillator obtaining an efficiency for the detection of this process of η n | Gd = 80% and a mean capture time τ = 25μs, in good agreement with the results obtained by the measures. This implies a gain of a factor ∼ 20 in the signal to noise ratio for neutron capture detection with respect to the undoped liquid scintillator. We discuss how the captures of neutrons from rock radioactivity on Gd modify the background conditions of the detector and we calculate the curves expressing the sensitivity to a ν-bar e burst from core collapse supernovae depending on the distance of the collapsing star. It results that doping the 1 kton Large Volume Detector with Gd would assure a 90% detection efficiency at the distance of the Large Magellanic Cloud (50 kpc), an achievement which is equivalent to that obtained by doubling the number of counters in LVD

  8. Development of a self-absorption correction method used for a HPGe detector by means of a Monte Carlo simulation

    International Nuclear Information System (INIS)

    Itadzu, Hidesuke; Iguchi, Tetsuo; Suzuki, Toshikazu

    2013-01-01

    Quantitative analysis for food products and natural samples, to determine the activity of each radionuclide, can be made by using a high-purity germanium (HPGe) gamma-ray spectrometer system. The analysis procedure is, in general, based upon the guidelines established by the Nuclear Safety Division of the Ministry of Education, Culture, Sports, Science and Technology in Japan (JP MEXT). In the case of gamma-ray spectrum analysis for large volume samples, re-entrant (marinelli) containers are commonly used. The effect of photon attenuation in a large-volume sample, so-called “self-absorption”, should be corrected for precise determination of the activity. As for marinelli containers, two accurate geometries are shown in the JP MEXT guidelines for 700 milliliter and 2 liter volumes. In the document, the functions to obtain the self-absorption coefficients for these specific shapes are also shown. Therefore, self-absorption corrections have been carried out only for these two containers with practical media. However, to measure radioactivity for samples in containers of volumes other than those described in the guidelines, the self-absorption correction functions must be obtained by measuring at least two standard multinuclide volume sources, which consist of different media or different linear attenuation coefficients. In this work, we developed a method to obtain these functions over a wide range of linear attenuation coefficients for self-absorption in various shapes of marinelli containers using a Monte Carlo simulation. This method was applied to a 1-liter marinelli container, which is widely used for the above quantitative analysis, although its self-absorption correction function has not yet been established. The validity of this method was experimentally checked through an analysis of natural samples with known activity levels. (author)

  9. ESB application for effective synchronization of large volume measurements data

    CERN Document Server

    Wyszkowski, Przemysław Michał

    2011-01-01

    The TOTEM experiment at CERN aims at measurement of total cross section, elastic scattering and diffractive processes of colliding protons in the Large Hadron Collider. In order for the research to be possible, it is necessary to process huge amounts of data coming from variety of sources: TOTEM detectors, CMS detectors, measurement devices around the Large Hadron Collider tunnel and many other external systems. Preparing final results involves also calculating plenty of intermediate figures, which also need to be stored. In order for the work of the scientist to be effective and convenient it is crucial to provide central point for the data storage, where all raw and intermediate figures will be stored. This thesis aims at presenting the usage of Enterprise Service Bus concept in building software infrastructure for transferring large volume of measurements data. Topics discussed here include technologies and mechanisms realizing the concept of integration bus, model of data transferring system based on ...

  10. SUSY’s Ladder: reframing sequestering at Large Volume

    Energy Technology Data Exchange (ETDEWEB)

    Reece, Matthew [Department of Physics, Harvard University,Cambridge, MA 02138 (United States); Xue, Wei [Center for Theoretical Physics, Massachusetts Institute of Technology,Cambridge, MA 02139 (United States)

    2016-04-07

    Theories with approximate no-scale structure, such as the Large Volume Scenario, have a distinctive hierarchy of multiple mass scales in between TeV gaugino masses and the Planck scale, which we call SUSY’s Ladder. This is a particular realization of Split Supersymmetry in which the same small parameter suppresses gaugino masses relative to scalar soft masses, scalar soft masses relative to the gravitino mass, and the UV cutoff or string scale relative to the Planck scale. This scenario has many phenomenologically interesting properties, and can avoid dangers including the gravitino problem, flavor problems, and the moduli-induced LSP problem that plague other supersymmetric theories. We study SUSY’s Ladder using a superspace formalism that makes the mysterious cancelations in previous computations manifest. This opens the possibility of a consistent effective field theory understanding of the phenomenology of these scenarios, based on power-counting in the small ratio of string to Planck scales. We also show that four-dimensional theories with approximate no-scale structure enforced by a single volume modulus arise only from two special higher-dimensional theories: five-dimensional supergravity and ten-dimensional type IIB supergravity. This gives a phenomenological argument in favor of ten dimensional ultraviolet physics which is different from standard arguments based on the consistency of superstring theory.

  11. An annular BF3 counter of large sensitive volume

    International Nuclear Information System (INIS)

    Janardhanan, S.; Swaminathan, N.

    1975-01-01

    An annular neutron counter having a large sensitive volume with inner and outer diameter 31 cms with multiple electrode system fabricated especially to measure the neutron output from fissile region of standard fast reactor fuel of length nearly equivalent to 500 cms is described. The counter efficiency is nearly 0.3% for neutron and sensitivity 0.0018 counts/neutron for (alpha, neutron) and spontaneous fission source. Its other potential applications which are indicated are : (1) quality control of fast reactor fuel pins (2) fuel inventory (3) assessing radioactivity of solid waste packets containing PuO 2 (4) uniformity of fuel loading of a reactor and (5) neutron monitoring in a fuel plant. (M.G.B.)

  12. Investigation of a large volume negative hydrogen ion source

    International Nuclear Information System (INIS)

    Courteille, C.; Bruneteau, A.M.; Bacal, M.

    1995-01-01

    The electron and negative ion densities and temperatures are reported for a large volume hybrid multicusp negative ion source. Based on the scaling laws an analysis is made of the plasma formation and loss processes. It is shown that the positive ions are predominantly lost to the walls, although the observed scaling law is n + ∝I 0.57 d . However, the total plasma loss scales linearly with the discharge current, in agreement with the theoretical model. The negative ion formation and loss is also discussed. It is shown that at low pressure (1 mTorr) the negative ion wall loss becomes a significant part of the total loss. The dependence of n - /n e versus the electron temperature is reported. When the negative ion wall loss is negligible, all the data on n - /n e versus the electron temperatures fit a single curve. copyright 1995 American Institute of Physics

  13. Dilute scintillators for large-volume tracking detectors

    Energy Technology Data Exchange (ETDEWEB)

    Reeder, R.A. (University of New Mexico, Albuquerque, NM (United States)); Dieterle, B.D. (University of New Mexico, Albuquerque, NM (United States)); Gregory, C. (University of New Mexico, Albuquerque, NM (United States)); Schaefer, F. (University of New Mexico, Albuquerque, NM (United States)); Schum, K. (University of New Mexico, Albuquerque, NM (United States)); Strossman, W. (University of California, Riverside, CA (United States)); Smith, D. (Embry-Riddle Aeronautical Univ., Prescott, AZ (United States)); Christofek, L. (Los Alamos National Lab., NM (United States)); Johnston, K. (Los Alamos National Lab., NM (United States)); Louis, W.C. (Los Alamos National Lab., NM (United States)); Schillaci, M. (Los Alamos National Lab., NM (United States)); Volta, M. (Los Alamos National Lab., NM (United States)); White, D.H. (Los Alamos National Lab., NM (United States)); Whitehouse, D. (Los Alamos National Lab., NM (United States)); Albert, M. (University of Pennsylvania, Phi

    1993-10-01

    Dilute scintillation mixtures emit isotropic light for both fast and slow particles, but retain the Cherenkov light cone from fast particles. Large volume detectors using photomultipliers to reconstruct relativistic tracks will also be sensitive to slow particles if they are filled with these mixtures. Our data show that 0.03 g/l of b-PBD in mineral oil has a 2.4:1 ratio (in the first 12 ns) of isotropic light to Cherenkov light for positron tracks. The light attenuation length is greater than 15 m for wavelength above 400 nm, and the scintillation decay time is about 2 ns for the fast component. There is also a slow isotropic light component that is larger (relative to the fast component) for protons than for electrons. This effect allows particle identification by a technique similar to pulse shape discrimination. These features will be utilized in LSND, a neutrino detector at LAMPF. (orig.)

  14. HPGe detectors timing using pulse shape analysis techniques

    International Nuclear Information System (INIS)

    Crespi, F.C.L.; Vandone, V.; Brambilla, S.; Camera, F.; Million, B.; Riboldi, S.; Wieland, O.

    2010-01-01

    In this work the Pulse Shape Analysis has been used to improve the time resolution of High Purity Germanium (HPGe) detectors. A set of time aligned signals was acquired in a coincidence measurement using a coaxial HPGe and a cerium-doped lanthanum chloride (LaCl 3 :Ce) scintillation detector. The analysis using a Constant Fraction Discriminator (CFD) time output versus the HPGe signal shape shows that time resolution ranges from 2 to 12 ns depending on the slope in the initial part of the signal. An optimization procedure of the CFD parameters gives the same final time resolution (8 ns) as the one achieved after a correction of the CFD output based on the current pulse maximum position. Finally, an algorithm based on Pulse Shape Analysis was applied to the experimental data and a time resolution between 3 and 4 ns was obtained, corresponding to a 50% improvement as compared with that given by standard CFDs.

  15. Development of portable HPGe spectrometer for in situ measurements

    Directory of Open Access Journals (Sweden)

    Kail Artjoms

    2015-01-01

    Full Text Available In situ applications require a very high level of portability of high-resolution spectrometric equipment. Usage of HPGe detectors for radioactivity measurements in the environment or for nuclear safeguard applications, to combat illicit trafficking of nuclear materials or uranium and plutonium monitoring in nuclear wastes, has become a norm in the recent years. Portable HPGe-based radionuclide spectrometer with electrical cooling has lately appeared on the market for in situ applications. At the same time deterioration of energy resolution associated with vibrations produced by cryocooler or high weight of the instrument, short time of autonomous operation and high price of these spectrometers are limiting their usage in many cases. In this paper we present development results of ultra compact hand held all-in-one spectrometer for in situ measurements based on HPGe detector cooled by liquid nitrogen without listing the above disadvantages.

  16. Uncertainty analysis in the simulation of an HPGe detector using the Monte Carlo Code MCNP5

    International Nuclear Information System (INIS)

    Gallardo, Sergio; Pozuelo, Fausto; Querol, Andrea; Verdu, Gumersindo; Rodenas, Jose; Ortiz, J.; Pereira, Claubia

    2013-01-01

    A gamma spectrometer including an HPGe detector is commonly used for environmental radioactivity measurements. Many works have been focused on the simulation of the HPGe detector using Monte Carlo codes such as MCNP5. However, the simulation of this kind of detectors presents important difficulties due to the lack of information from manufacturers and due to loss of intrinsic properties in aging detectors. Some parameters such as the active volume or the Ge dead layer thickness are many times unknown and are estimated during simulations. In this work, a detailed model of an HPGe detector and a petri dish containing a certified gamma source has been done. The certified gamma source contains nuclides to cover the energy range between 50 and 1800 keV. As a result of the simulation, the Pulse Height Distribution (PHD) is obtained and the efficiency curve can be calculated from net peak areas and taking into account the certified activity of the source. In order to avoid errors due to the net area calculation, the simulated PHD is treated using the GammaVision software. On the other hand, it is proposed to use the Noether-Wilks formula to do an uncertainty analysis of model with the main goal of determining the efficiency curve of this detector and its associated uncertainty. The uncertainty analysis has been focused on dead layer thickness at different positions of the crystal. Results confirm the important role of the dead layer thickness in the low energy range of the efficiency curve. In the high energy range (from 300 to 1800 keV) the main contribution to the absolute uncertainty is due to variations in the active volume. (author)

  17. Uncertainty analysis in the simulation of an HPGe detector using the Monte Carlo Code MCNP5

    Energy Technology Data Exchange (ETDEWEB)

    Gallardo, Sergio; Pozuelo, Fausto; Querol, Andrea; Verdu, Gumersindo; Rodenas, Jose, E-mail: sergalbe@upv.es [Universitat Politecnica de Valencia, Valencia, (Spain). Instituto de Seguridad Industrial, Radiofisica y Medioambiental (ISIRYM); Ortiz, J. [Universitat Politecnica de Valencia, Valencia, (Spain). Servicio de Radiaciones. Lab. de Radiactividad Ambiental; Pereira, Claubia [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Departamento de Engenharia Nuclear

    2013-07-01

    A gamma spectrometer including an HPGe detector is commonly used for environmental radioactivity measurements. Many works have been focused on the simulation of the HPGe detector using Monte Carlo codes such as MCNP5. However, the simulation of this kind of detectors presents important difficulties due to the lack of information from manufacturers and due to loss of intrinsic properties in aging detectors. Some parameters such as the active volume or the Ge dead layer thickness are many times unknown and are estimated during simulations. In this work, a detailed model of an HPGe detector and a petri dish containing a certified gamma source has been done. The certified gamma source contains nuclides to cover the energy range between 50 and 1800 keV. As a result of the simulation, the Pulse Height Distribution (PHD) is obtained and the efficiency curve can be calculated from net peak areas and taking into account the certified activity of the source. In order to avoid errors due to the net area calculation, the simulated PHD is treated using the GammaVision software. On the other hand, it is proposed to use the Noether-Wilks formula to do an uncertainty analysis of model with the main goal of determining the efficiency curve of this detector and its associated uncertainty. The uncertainty analysis has been focused on dead layer thickness at different positions of the crystal. Results confirm the important role of the dead layer thickness in the low energy range of the efficiency curve. In the high energy range (from 300 to 1800 keV) the main contribution to the absolute uncertainty is due to variations in the active volume. (author)

  18. Dark Radiation predictions from general Large Volume Scenarios

    Science.gov (United States)

    Hebecker, Arthur; Mangat, Patrick; Rompineve, Fabrizio; Witkowski, Lukas T.

    2014-09-01

    Recent observations constrain the amount of Dark Radiation (Δ N eff ) and may even hint towards a non-zero value of Δ N eff . It is by now well-known that this puts stringent constraints on the sequestered Large Volume Scenario (LVS), i.e. on LVS realisations with the Standard Model at a singularity. We go beyond this setting by considering LVS models where SM fields are realised on 7-branes in the geometric regime. As we argue, this naturally goes together with high-scale supersymmetry. The abundance of Dark Radiation is determined by the competition between the decay of the lightest modulus to axions, to the SM Higgs and to gauge fields, and leads to strict constraints on these models. Nevertheless, these constructions can in principle meet current DR bounds due to decays into gauge bosons alone. Further, a rather robust prediction for a substantial amount of Dark Radiation can be made. This applies both to cases where the SM 4-cycles are stabilised by D-terms and are small `by accident', i.e. tuning, as well as to fibred models with the small cycles stabilised by loops. In these constructions the DR axion and the QCD axion are the same field and we require a tuning of the initial misalignment to avoid Dark Matter overproduction. Furthermore, we analyse a closely related setting where the SM lives at a singularity but couples to the volume modulus through flavour branes. We conclude that some of the most natural LVS settings with natural values of model parameters lead to Dark Radiation predictions just below the present observational limits. Barring a discovery, rather modest improvements of present Dark Radiation bounds can rule out many of these most simple and generic variants of the LVS.

  19. Study on water boiling noises in a large volume

    International Nuclear Information System (INIS)

    Masagutov, R.F.; Krivtsov, V.A.

    1977-01-01

    Presented are the results of measurement of the noise spectra during boiling of water in a large volume at the pressure of 1 at. Boiling of the distilled water has been accomplished with the use of the heaters made of the Kh18N10T steel, 50 mm in length, 2 mm in the outside diameter, with the wall thickness of 0.1 mm. The degree of water under heating changed during the experiments from 0 to 80 deg C, and the magnitude of the specific heat flux varied from o to 0.7 - 0.9 qsup(x), where qsup(x) was the specific heat flux of the tube burn-out. The noise spectrum of the boiling water was analyzed at frequencies of 0.5 to 200 kHz. The submerge-type pressure-electric transmitters were used for measurements. At underheating boiling during the experiment the standing waves have formed which determine the structure of the measured spectra. During saturated boiling of water no standing waves were revealed. At underheating over 15 - 20 deg C the water boiling process is accompanied by the noises within the ultrasonic frequency range. The maximum upper boundary of the noise in the experiments amounts to 90 - 100 kHz

  20. Prospects for accelerator neutron sources for large volume minerals analysis

    International Nuclear Information System (INIS)

    Clayton, C.G.; Spackman, R.

    1988-01-01

    The electron Linac can be regarded as a practical source of thermal neutrons for activation analysis of large volume mineral samples. With a suitable target and moderator, a neutron flux of about 10 10 n/cm/s over 2-3 kg of rock can be generated. The proton Linac gives the possibility of a high neutron yield (> 10 12 n/s) of fast neutrons at selected energies. For the electron Linac, targets of W-U and W-Be are discussed. The advantages and limitations of the system are demonstrated for the analysis of gold in rocks and ores and for platinum in chromitite. These elements were selected as they are most likely to justify an accelerator installation at the present time. Errors due to self shielding in gold particles for thermal neutrons are discussed. The proton Linac is considered for neutrons generated from a lithium target through the 7 Li(p, n) 7 Be reaction. The analysis of gold by fast neutron activation is considered. This approach avoids particle self-absorption and, by appropriate proton energy selection, avoids potentially dominating interfering reactions. The analysis of 235 U in the presence of 238 U and 232 Th is also considered. (author)

  1. Performance of HPGe detectors in high magnetic fields

    Czech Academy of Sciences Publication Activity Database

    Lorente, A.S.; Achenbach, P.; Agnello, M.; Majling, Lubomír

    2007-01-01

    Roč. 573, č. 3 (2007), s. 410-417 ISSN 0168-9002 R&D Projects: GA ČR GA202/05/2142 Institutional research plan: CEZ:AV0Z10480505 Keywords : hypernuclear gamma-spectroscopy * HPGe detectors Subject RIV: BE - Theoretical Physics Impact factor: 1.114, year: 2007

  2. Topologically-based visualization of large-scale volume data

    International Nuclear Information System (INIS)

    Takeshima, Y.; Tokunaga, M.; Fujishiro, I.; Takahashi, S.

    2004-01-01

    Due to the recent progress in the performance of computing/measurement environments and the advent of ITBL environments, volume datasets have become larger and more complicated. Although computer visualization is one of the tools to analyze such datasets effectively, it is almost impossible to adjust the visualization parameter value by trial and error without taking the feature of a given volume dataset into consideration. In this article, we introduce a scheme of topologically-based volume visualization, which is intended to choose appropriate visualization parameter values automatically through topological volume skeletonization. (author)

  3. Using lattice tools and unfolding methods for hpge detector efficiency simulation with the Monte Carlo code MCNP5

    International Nuclear Information System (INIS)

    Querol, A.; Gallardo, S.; Ródenas, J.; Verdú, G.

    2015-01-01

    In environmental radioactivity measurements, High Purity Germanium (HPGe) detectors are commonly used due to their excellent resolution. Efficiency calibration of detectors is essential to determine activity of radionuclides. The Monte Carlo method has been proved to be a powerful tool to complement efficiency calculations. In aged detectors, efficiency is partially deteriorated due to the dead layer increasing and consequently, the active volume decreasing. The characterization of the radiation transport in the dead layer is essential for a realistic HPGe simulation. In this work, the MCNP5 code is used to calculate the detector efficiency. The F4MESH tally is used to determine the photon and electron fluence in the dead layer and the active volume. The energy deposited in the Ge has been analyzed using the ⁎F8 tally. The F8 tally is used to obtain spectra and to calculate the detector efficiency. When the photon fluence and the energy deposition in the crystal are known, some unfolding methods can be used to estimate the activity of a given source. In this way, the efficiency is obtained and serves to verify the value obtained by other methods. - Highlights: • The MCNP5 code is used to estimate the dead layer thickness of an HPGe detector. • The F4MESH tally is applied to verify where interactions occur into the Ge crystal. • PHD and the energy deposited are obtained with F8 and ⁎F8 tallies, respectively. • An average dead layer between 70 and 80 µm is obtained for the HPGe studied. • The efficiency is calculated applying the TSVD method to the response matrix.

  4. An experimental study on the excitation of large volume airguns in a small volume body of water

    International Nuclear Information System (INIS)

    Wang, Baoshan; Yang, Wei; Yuan, Songyong; Ge, Hongkui; Chen, Yong; Guo, Shijun; Xu, Ping

    2010-01-01

    A large volume airgun array is effective in generating seismic waves, which is extensively used in large volume bodies of water such as oceans, lakes and reservoirs. So far, the application of large volume airguns is subject to the distribution of large volume bodies of water. This paper reports an attempt to utilize large volume airguns in a small body of water as a seismic source for seismotectonic studies. We carried out a field experiment in Mapaoquan pond, Fangshan district, Beijing, during the period 25–30 May 2009. Bolt LL1500 airguns, each with volumes of 2000 in 3 , the largest commercial airguns available today, were used in this experiment. We tested the excitation of the airgun array with one or two guns. The airgun array was placed 7–11 m below the water's surface. The near- and far-field seismic motions induced by the airgun source were recorded by a 100 km long seismic profile composed of 16 portable seismometers and a 100 m long strong motion seismograph profile, respectively. The following conclusions can be drawn from this experiment. First, it is feasible to excite large volume airguns in a small volume body of water. Second, seismic signals from a single shot of one airgun can be recognized at the offset up to 15 km. Taking advantage of high source repeatability, we stacked records from 128 shots to enhance the signal-to-noise ratio, and direct P-waves can be easily identified at the offset ∼50 km in stacked records. Third, no detectable damage to fish or near-field constructions was caused by the airgun shots. Those results suggest that large volume airguns excited in small bodies of water can be used as a routinely operated seismic source for mid-scale (tens of kilometres) subsurface explorations and monitoring under various running conditions

  5. Development of Educational Simulation on Spectrum of HPGe Detector and Implementation of Education Program

    International Nuclear Information System (INIS)

    Seo, K. W.; Joo, Y. C.; Ji, Y. J.; Lee, M. O.; Lee, S. Y.; Jun, Y. K.

    2005-12-01

    In this development, characteristics of Aptec, Genie2000(Canberra Co, USA), GammaVision(Ortec Co, USA) which are usually used in Korea radioactive measure laboratory, such as peak search, peak fitting, central area position and area calculation, spectrum correction and method for radioactive calculation are included. And radioactive source geometry, absorption of sample itself, methods for correcting coincidence summing effect is developed and the result effected on spectrum analysis teaching material. Developed simulation HPGe detector spectrum are spectrum for correction, spectrum for correcting radio source-detection duration geometry, sample spectrum which need self absorption correction of radio source, peak search spectrum for optimizing peak search offset setting and background spectrum. These spectrum are made similar to real spectrum by processing peak and background which were measured from mix standard volume radio source. Spectrum analysis teaching material is developed more focus on practical thing than theoretical thing, simulation spectrum must be used in spectrum analysis practise. Optimal method for spectrum analysis condition, spectrum correction, Geometry correction and background spectrum analysis are included in teaching material and also ANSI N42 recommended 'Spectrum analysis program test' procedure is included too. Aptec, Genie2000, Gamma Vision software manuals are included in appendix. In order to check the text of developed simulation on spectrum of HPGe detector, in 2004 and 2005, these was implemented in the other regular course as a course for superviser of the handling with RI. And the text and practical procedure were reviewed through the course and were revised

  6. Development of the MCNPX model for the portable HPGe detector

    International Nuclear Information System (INIS)

    Koleska, Michal; Viererbl, Ladislav; Marek, Milan

    2014-01-01

    The portable HPGe coaxial detector Canberra Big MAC is used in LVR-15 research reactor for spectrometric measurement of spent nuclear fuel. The fuel is measured in the dedicated system located in the spent fuel pool situated near the reactor. For the purpose of the spectrometric system calibration, the detector was precisely modeled with the MCNPX code. This model was constructed with the data acquired from the technical specification provided by the manufacturer and from the data obtained by the radiography of the crystal. The detector model was verified on the experimental data measured with available standard radionuclide sources and on-site prepared 110m Ag source. - Highlights: • Inner structure of the HPGe detector is determined. • An MCNPX model of the detector is developed. • The model is verified using different sources for two measurement geometries

  7. Performance of large electron energy filter in large volume plasma device

    International Nuclear Information System (INIS)

    Singh, S. K.; Srivastava, P. K.; Awasthi, L. M.; Mattoo, S. K.; Sanyasi, A. K.; Kaw, P. K.; Singh, R.

    2014-01-01

    This paper describes an in-house designed large Electron Energy Filter (EEF) utilized in the Large Volume Plasma Device (LVPD) [S. K. Mattoo, V. P. Anita, L. M. Awasthi, and G. Ravi, Rev. Sci. Instrum. 72, 3864 (2001)] to secure objectives of (a) removing the presence of remnant primary ionizing energetic electrons and the non-thermal electrons, (b) introducing a radial gradient in plasma electron temperature without greatly affecting the radial profile of plasma density, and (c) providing a control on the scale length of gradient in electron temperature. A set of 19 independent coils of EEF make a variable aspect ratio, rectangular solenoid producing a magnetic field (B x ) of 100 G along its axis and transverse to the ambient axial field (B z ∼ 6.2 G) of LVPD, when all its coils are used. Outside the EEF, magnetic field reduces rapidly to 1 G at a distance of 20 cm from the center of the solenoid on either side of target and source plasma. The EEF divides LVPD plasma into three distinct regions of source, EEF and target plasma. We report that the target plasma (n e ∼ 2 × 10 11  cm −3 and T e ∼ 2 eV) has no detectable energetic electrons and the radial gradients in its electron temperature can be established with scale length between 50 and 600 cm by controlling EEF magnetic field. Our observations reveal that the role of the EEF magnetic field is manifested by the energy dependence of transverse electron transport and enhanced transport caused by the plasma turbulence in the EEF plasma

  8. Large-volume injection in gas chromatographic trace analysis using temperature-programmable (PTV) injectors

    NARCIS (Netherlands)

    Mol, J.G.J.; Janssen, J.G.M.; Cramers, C.A.M.G.; Brinkman, U.A.T.

    1996-01-01

    The use of programmed-temperature vaporising (PTV) injectors for large-volume injection in capillary gas chromatography is briefly reviewed. The principles and optimisation of large-volume PTV injection are discussed. Guidelines are given for selection of the PTV conditions and injection mode for

  9. Calibration of a large volume argon-41 gas-effluent monitor

    International Nuclear Information System (INIS)

    Wilson, William E.; Lovas, Thomas A.

    1976-01-01

    In September of 1975, a large volume Argon-41 sampler was calibrated using a series connected calibration chamber of known sensitivity and a constant flow of activated Argon gas. The calibration included analysis of the effects of flow rate through the large volume sampler and yielded a calibration constant of 2.34 x 10 -8 μc/cm 3 /CPM. (author)

  10. Transporting large volumes of residual radioactive material: FUSRAP solutions

    International Nuclear Information System (INIS)

    Pressnell, T.; McDaniel, P.; Darby, J.

    1997-01-01

    During the 1940s, 1950s and 1960s, many sites in the United States were used by the Manhattan Engineer District and the Atomic Energy Commission for processing and storing uranium and thorium ores and metals. Some of the sites were owned by the federal government; others were owned by universities or other institutions; and still others, such as chemical plants, were privately owned. The Formerly Utilized Sites Remedial Action Program (FUSRAP) is one of several U.S. Department of Energy programs created to address radioactive contamination in excess of guidelines at these sites. FUSRAP currently includes 46 sites in 14 states. This article includes the following topics in describing FUSRAP work: Logistics challenges; engineering challenges (package inspection, equipment compatability, moisture content requirements, waste volume estimation); Traffic management

  11. Multi-hadron spectroscopy in a large physical volume

    DEFF Research Database (Denmark)

    Bulava, John; Hörz, Ben; Morningstar, Colin

    2018-01-01

    We demonstrate the effcacy of the stochastic LapH method to treat all-toall quark propagation on a Nf = 2 + 1 CLS ensemble with large linear spatial extent L = 5:5 fm, allowing us to obtain the benchmark elastic isovector p-wave pion-pion scattering amplitude to good precision already on a relati...

  12. GRABGAM Analysis of Ultra-Low-Level HPGe Gamma Spectra

    International Nuclear Information System (INIS)

    Winn, W.G.

    1999-01-01

    The GRABGAM code has been used successfully for ultra-low level HPGe gamma spectrometry analysis since its development in 1985 at Savannah River Technology Center (SRTC). Although numerous gamma analysis codes existed at that time, reviews of institutional and commercial codes indicated that none addressed all features that were desired by SRTC. Furthermore, it was recognized that development of an in-house code would better facilitate future evolution of the code to address SRTC needs based on experience with low-level spectra. GRABGAM derives its name from Gamma Ray Analysis BASIC Generated At MCA/PC

  13. MCNP HPGe detector benchmark with previously validated Cyltran model.

    Science.gov (United States)

    Hau, I D; Russ, W R; Bronson, F

    2009-05-01

    An exact copy of the detector model generated for Cyltran was reproduced as an MCNP input file and the detection efficiency was calculated similarly with the methodology used in previous experimental measurements and simulation of a 280 cm(3) HPGe detector. Below 1000 keV the MCNP data correlated to the Cyltran results within 0.5% while above this energy the difference between MCNP and Cyltran increased to about 6% at 4800 keV, depending on the electron cut-off energy.

  14. GRABGAM Analysis of Ultra-Low-Level HPGe Gamma Spectra

    Energy Technology Data Exchange (ETDEWEB)

    Winn, W.G.

    1999-07-28

    The GRABGAM code has been used successfully for ultra-low level HPGe gamma spectrometry analysis since its development in 1985 at Savannah River Technology Center (SRTC). Although numerous gamma analysis codes existed at that time, reviews of institutional and commercial codes indicated that none addressed all features that were desired by SRTC. Furthermore, it was recognized that development of an in-house code would better facilitate future evolution of the code to address SRTC needs based on experience with low-level spectra. GRABGAM derives its name from Gamma Ray Analysis BASIC Generated At MCA/PC.

  15. Dose measurements with a HPGe detector - a technical manual

    Energy Technology Data Exchange (ETDEWEB)

    Lidstroem, K.; Nordenfors, C.; Aagren, G

    2000-06-01

    This paper is a technical manual for estimations of dose based on a gamma spectrum. The method used is based on the Monte Carlo code EGS4. Since dose estimations from spectra are specific for each detector, this work is performed on two mobile HPGe detectors at FOA NBC Defence in Umeaa. This technical manual describes the method used in three steps: Part 1 explains how to construct a model of the detector geometry and the specific material for a new detector. Part 2 describes the underlying work of Monte Carlo simulations of a detector given geometry and material. Part 3 describes dose estimations from a gamma spectrum.

  16. Special Properties of Coherence Scanning Interferometers for large Measurement Volumes

    International Nuclear Information System (INIS)

    Bauer, W

    2011-01-01

    In contrast to many other optical methods the uncertainty of Coherence Scanning Interferometer (CSI) in vertical direction is independent from the field of view. Therefore CSIs are ideal instruments for measuring 3D-profiles of larger areas (36x28mm 2 , e.g.) with high precision. This is of advantage for the determination of form parameters like flatness, parallelism and steps heights within a short time. In addition, using a telecentric beam path allows measurements of deep lying surfaces (<70mm) and the determination of form parameters with large step-heights. The lateral and spatial resolution, however, are reduced. In this presentation different metrological characteristics together with their potential errors are analyzed for large-scale measuring CSIs. Therefore these instruments are ideal tools in quality control for good/bad selections, e.g. The consequences for the practical use in industry and for standardization are discussed by examples of workpieces of automotive suppliers or from the steel industry.

  17. Radiation from Large Gas Volumes and Heat Exchange in Steam Boiler Furnaces

    Energy Technology Data Exchange (ETDEWEB)

    Makarov, A. N., E-mail: tgtu-kafedra-ese@mail.ru [Tver State Technical University (Russian Federation)

    2015-09-15

    Radiation from large cylindrical gas volumes is studied as a means of simulating the flare in steam boiler furnaces. Calculations of heat exchange in a furnace by the zonal method and by simulation of the flare with cylindrical gas volumes are described. The latter method is more accurate and yields more reliable information on heat transfer processes taking place in furnaces.

  18. Relative efficiency calculation of a HPGe detector using MCNPX code

    International Nuclear Information System (INIS)

    Medeiros, Marcos P.C.; Rebello, Wilson F.; Lopes, Jose M.; Silva, Ademir X.

    2015-01-01

    High-purity germanium detectors (HPGe) are mandatory tools for spectrometry because of their excellent energy resolution. The efficiency of such detectors, quoted in the list of specifications by the manufacturer, frequently refers to the relative full-energy peak efficiency, related to the absolute full-energy peak efficiency of a 7.6 cm x 7.6 cm (diameter x height) NaI(Tl) crystal, based on the 1.33 MeV peak of a 60 Co source positioned 25 cm from the detector. In this study, we used MCNPX code to simulate a HPGe detector (Canberra GC3020), from Real-Time Neutrongraphy Laboratory of UFRJ, to survey the spectrum of a 60 Co source located 25 cm from the detector in order to calculate and confirm the efficiency declared by the manufacturer. Agreement between experimental and simulated data was achieved. The model under development will be used for calculating and comparison purposes with the detector calibration curve from software Genie2000™, also serving as a reference for future studies. (author)

  19. Center-stabilized Yang-Mills Theory:Confinement and Large N Volume Independence

    International Nuclear Information System (INIS)

    Unsal, Mithat; Yaffe, Laurence G.

    2008-01-01

    We examine a double trace deformation of SU(N) Yang-Mills theory which, for large N and large volume, is equivalent to unmodified Yang-Mills theory up to O(1/N 2 ) corrections. In contrast to the unmodified theory, large N volume independence is valid in the deformed theory down to arbitrarily small volumes. The double trace deformation prevents the spontaneous breaking of center symmetry which would otherwise disrupt large N volume independence in small volumes. For small values of N, if the theory is formulated on R 3 x S 1 with a sufficiently small compactification size L, then an analytic treatment of the non-perturbative dynamics of the deformed theory is possible. In this regime, we show that the deformed Yang-Mills theory has a mass gap and exhibits linear confinement. Increasing the circumference L or number of colors N decreases the separation of scales on which the analytic treatment relies. However, there are no order parameters which distinguish the small and large radius regimes. Consequently, for small N the deformed theory provides a novel example of a locally four-dimensional pure gauge theory in which one has analytic control over confinement, while for large N it provides a simple fully reduced model for Yang-Mills theory. The construction is easily generalized to QCD and other QCD-like theories

  20. Center-stabilized Yang-Mills theory: Confinement and large N volume independence

    International Nuclear Information System (INIS)

    Uensal, Mithat; Yaffe, Laurence G.

    2008-01-01

    We examine a double trace deformation of SU(N) Yang-Mills theory which, for large N and large volume, is equivalent to unmodified Yang-Mills theory up to O(1/N 2 ) corrections. In contrast to the unmodified theory, large N volume independence is valid in the deformed theory down to arbitrarily small volumes. The double trace deformation prevents the spontaneous breaking of center symmetry which would otherwise disrupt large N volume independence in small volumes. For small values of N, if the theory is formulated on R 3 xS 1 with a sufficiently small compactification size L, then an analytic treatment of the nonperturbative dynamics of the deformed theory is possible. In this regime, we show that the deformed Yang-Mills theory has a mass gap and exhibits linear confinement. Increasing the circumference L or number of colors N decreases the separation of scales on which the analytic treatment relies. However, there are no order parameters which distinguish the small and large radius regimes. Consequently, for small N the deformed theory provides a novel example of a locally four-dimensional pure-gauge theory in which one has analytic control over confinement, while for large N it provides a simple fully reduced model for Yang-Mills theory. The construction is easily generalized to QCD and other QCD-like theories.

  1. New approach for calibration the efficiency of HPGe detectors

    International Nuclear Information System (INIS)

    Alnour, I.A.; Wagiran, H.; Suhaimi Hamzah; Siong, W.B.; Mohd Suhaimi Elias

    2013-01-01

    Full-text: This work evaluates the efficiency calibrating of HPGe detector coupled with Canberra GC3018 with Genie 2000 software and Ortec GEM25-76-XLB-C with Gamma Vision software; available at Neutron activation analysis laboratory in Malaysian Nuclear Agency (NM). The efficiency calibration curve was constructed from measurement of an IAEA, standard gamma point sources set composed by 214 Am, 57 Co, 133 Ba, 152 Eu, 137 Cs and 60 Co. The efficiency calibrations were performed for three different geometries: 5, 10 and 15 cm distances from the end cap detector. The polynomial parameters functions were simulated through a computer program, MATLAB in order to find an accurate fit to the experimental data points. The efficiency equation was established from the known fitted parameters which allow for the efficiency evaluation at particular energy of interest. The study shows that significant deviations in the efficiency, depending on the source-detector distance and photon energy. (author)

  2. 21 CFR 201.323 - Aluminum in large and small volume parenterals used in total parenteral nutrition.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Aluminum in large and small volume parenterals... for Specific Drug Products § 201.323 Aluminum in large and small volume parenterals used in total parenteral nutrition. (a) The aluminum content of large volume parenteral (LVP) drug products used in total...

  3. Response function of a p type - HPGe detector

    International Nuclear Information System (INIS)

    Lopez-Pino, Neivy; Cabral, Fatima Padilla; D'Alessandro, Katia; Maidana, Nora Lia; Vanin, Vito Roberto

    2011-01-01

    The response function of a HPGe detector depends on Ge crystal dimensions and dead layers thicknesses; most of them are not given by the manufacturers or change with detector damage from neutrons or contact with the atmosphere and therefore must be experimentally determined. The response function is obtained by a Monte-Carlo simulation procedure based on the Ge crystal characteristics. In this work, a p-type coaxial HPGe detector with 30% efficiency, manufactured in 1989, was investigated. The crystal radius and length and the inner hole dimensions were obtained scanning the capsule both in the radial and axial directions using 4 mm collimated beams from 137 Cs, 207 Bi point sources placed on a x-y table in steps of 2,00 mm. These dimensions were estimated comparing the experimental peak areas with those obtained by simulation using several hole configurations. In a similar procedure, the frontal dead layer thickness was determined using 2 mm collimated beams of the 59 keV gamma-rays from 241 Am and 81 keV from 133 Ba sources hitting the detector at 90 deg and 45 deg with respect to the capsule surface. The Monte Carlo detector model included, besides the crystal, hole and capsules sizes, the Ge dead-layers. The obtained spectra were folded with a gaussian resolution function to account for electronic noise. The comparison of simulated and experimental response functions for 4 mm collimated beams of 60 Co, 137 Cs, and 207 Bi points sources placed at distances of 7, 11 and 17 cm from the detector end cap showed relative deviations of about 10% in general and below 10% in the peak. The frontal dead layer thickness determined by our procedure was different from that specified by the detector manufacturer. (author)

  4. Development of large-volume rhyolitic ignibrites (LRI'S): The Chalupas Caldera, an example from Ecuador

    International Nuclear Information System (INIS)

    Hammersley, L.; DePaolo, D.J; Beate, B

    2001-01-01

    The mechanisms responsible for the generation of large volumes of silicic magma and the eruption of large-volume rhyolitic ignimbrites (LRI's) remain poorly understood. Of particular interest are the relative roles of crustal assimilation, fractional crystallization and magma supply and the processes by which large volumes of magma accumulate in crustal chambers rather than erupt in smaller batches. Isotope geochemistry, combined with study of major and trace element variations of lavas, can be used to infer the relative contribution of crustal material and continued magmatic supply. Timescales for the accumulation of magma can be estimated using detailed geochronology. Magma supply rates can be estimated from eruption rates of nearby volcanoes. In this study we investigate the evolution of the Chalupas LRI, a caldera system in the Ecuadorian Andes where LRI's are rare in comparison to the Southern Volcanic Zone (SVZ) of South America (au)

  5. Refined universal laws for hull volumes and perimeters in large planar maps

    International Nuclear Information System (INIS)

    Guitter, Emmanuel

    2017-01-01

    We consider ensembles of planar maps with two marked vertices at distance k from each other, and look at the closed line separating these vertices and lying at distance d from the first one ( d   <   k ). This line divides the map into two components, the hull at distance d which corresponds to the part of the map lying on the same side as the first vertex and its complementary. The number of faces within the hull is called the hull volume, and the length of the separating line the hull perimeter. We study the statistics of the hull volume and perimeter for arbitrary d and k in the limit of infinitely large planar quadrangulations, triangulations and Eulerian triangulations. We consider more precisely situations where both d and k become large with the ratio d / k remaining finite. For infinitely large maps, two regimes may be encountered: either the hull has a finite volume and its complementary is infinitely large, or the hull itself has an infinite volume and its complementary is of finite size. We compute the probability for the map to be in either regime as a function of d / k as well as a number of universal statistical laws for the hull perimeter and volume when maps are conditioned to be in one regime or the other. (paper)

  6. Large Volume, Behaviorally-relevant Illumination for Optogenetics in Non-human Primates.

    Science.gov (United States)

    Acker, Leah C; Pino, Erica N; Boyden, Edward S; Desimone, Robert

    2017-10-03

    This protocol describes a large-volume illuminator, which was developed for optogenetic manipulations in the non-human primate brain. The illuminator is a modified plastic optical fiber with etched tip, such that the light emitting surface area is > 100x that of a conventional fiber. In addition to describing the construction of the large-volume illuminator, this protocol details the quality-control calibration used to ensure even light distribution. Further, this protocol describes techniques for inserting and removing the large volume illuminator. Both superficial and deep structures may be illuminated. This large volume illuminator does not need to be physically coupled to an electrode, and because the illuminator is made of plastic, not glass, it will simply bend in circumstances when traditional optical fibers would shatter. Because this illuminator delivers light over behaviorally-relevant tissue volumes (≈ 10 mm 3 ) with no greater penetration damage than a conventional optical fiber, it facilitates behavioral studies using optogenetics in non-human primates.

  7. Rejecting escape events in large volume Ge detectors by a pulse shape selection procedure

    International Nuclear Information System (INIS)

    Del Zoppo, A.; Agodi, C.; Alba, R.; Bellia, G.; Coniglione, R.; Loukachine, K.; Maiolino, C.; Migneco, E.; Piattelli, P.; Santonocito, D.; Sapienza, P.

    1993-01-01

    The dependence of the response to γ-rays of a large volume Ge detector on the interval width of a selected initial rise pulse slope is investigated. The number of escape events associated with a small pulse slope is found to be greater than the corresponding number of full energy events. An escape event rejection procedure based on the observed correlation between energy deposition and pulse shape is discussed. Such a procedure seems particularly suited for the design of highly granular large volume Ge detector arrays. (orig.)

  8. Feasibility of large volume casting cementation process for intermediate level radioactive waste

    International Nuclear Information System (INIS)

    Chen Zhuying; Chen Baisong; Zeng Jishu; Yu Chengze

    1988-01-01

    The recent tendency of radioactive waste treatment and disposal both in China and abroad is reviewed. The feasibility of the large volume casting cementation process for treating and disposing the intermediate level radioactive waste from spent fuel reprocessing plant in shallow land is assessed on the basis of the analyses of the experimental results (such as formulation study, solidified radioactive waste properties measurement ect.). It can be concluded large volume casting cementation process is a promising, safe and economic process. It is feasible to dispose the intermediate level radioactive waste from reprocessing plant it the disposal site chosen has resonable geological and geographical conditions and some additional effective protection means are taken

  9. Measurement of β-decay end point energy with planar HPGe detector

    Science.gov (United States)

    Bhattacharjee, T.; Pandit, Deepak; Das, S. K.; Chowdhury, A.; Das, P.; Banerjee, D.; Saha, A.; Mukhopadhyay, S.; Pal, S.; Banerjee, S. R.

    2014-12-01

    The β - γ coincidence measurement has been performed with a segmented planar Hyper-Pure Germanium (HPGe) detector and a single coaxial HPGe detector to determine the end point energies of nuclear β-decays. The experimental end point energies have been determined for some of the known β-decays in 106Rh →106Pd. The end point energies corresponding to three weak branches in 106Rh →106Pd decay have been measured for the first time. The γ ray and β particle responses for the planar HPGe detector were simulated using the Monte Carlo based code GEANT3. The experimentally obtained β spectra were successfully reproduced with the simulation.

  10. Rapid estimate of solid volume in large tuff cores using a gas pycnometer

    International Nuclear Information System (INIS)

    Thies, C.; Geddis, A.M.; Guzman, A.G.

    1996-09-01

    A thermally insulated, rigid-volume gas pycnometer system has been developed. The pycnometer chambers have been machined from solid PVC cylinders. Two chambers confine dry high-purity helium at different pressures. A thick-walled design ensures minimal heat exchange with the surrounding environment and a constant volume system, while expansion takes place between the chambers. The internal energy of the gas is assumed constant over the expansion. The ideal gas law is used to estimate the volume of solid material sealed in one of the chambers. Temperature is monitored continuously and incorporated into the calculation of solid volume. Temperature variation between measurements is less than 0.1 degrees C. The data are used to compute grain density for oven-dried Apache Leap tuff core samples. The measured volume of solid and the sample bulk volume are used to estimate porosity and bulk density. Intrinsic permeability was estimated from the porosity and measured pore surface area and is compared to in-situ measurements by the air permeability method. The gas pycnometer accommodates large core samples (0.25 m length x 0.11 m diameter) and can measure solid volume greater than 2.20 cm 3 with less than 1% error

  11. Rapid estimate of solid volume in large tuff cores using a gas pycnometer

    Energy Technology Data Exchange (ETDEWEB)

    Thies, C. [ed.; Geddis, A.M.; Guzman, A.G. [and others

    1996-09-01

    A thermally insulated, rigid-volume gas pycnometer system has been developed. The pycnometer chambers have been machined from solid PVC cylinders. Two chambers confine dry high-purity helium at different pressures. A thick-walled design ensures minimal heat exchange with the surrounding environment and a constant volume system, while expansion takes place between the chambers. The internal energy of the gas is assumed constant over the expansion. The ideal gas law is used to estimate the volume of solid material sealed in one of the chambers. Temperature is monitored continuously and incorporated into the calculation of solid volume. Temperature variation between measurements is less than 0.1{degrees}C. The data are used to compute grain density for oven-dried Apache Leap tuff core samples. The measured volume of solid and the sample bulk volume are used to estimate porosity and bulk density. Intrinsic permeability was estimated from the porosity and measured pore surface area and is compared to in-situ measurements by the air permeability method. The gas pycnometer accommodates large core samples (0.25 m length x 0.11 m diameter) and can measure solid volume greater than 2.20 cm{sup 3} with less than 1% error.

  12. Large-volume static compression using nano-polycrystalline diamond for opposed anvils in compact cells

    International Nuclear Information System (INIS)

    Okuchi, T; Sasaki, S; Ohno, Y; Osakabe, T; Odake, S; Kagi, H

    2010-01-01

    In order to extend the pressure regime of intrinsically low-sensitivity methods of measurement, such as neutron scattering and NMR, sample volume to be compressed in compact opposed-anvil cells is desired to be significantly increased. We hereby conducted a series of experiments using two types of compact cells equipped with enforced loading mechanisms. Super-hard nano-polycrystalline diamond (NPD) anvils were carefully prepared for large-volume compression in these cells. These anvils are harder, larger and stronger than single crystal diamond anvils, so that they could play an ideal role to accept the larger forces. Supported and unsupported anvil geometries were separately tested to evaluate this expectation. In spite of insufficient support to the anvils, pressures to 14 GPa were generated for the sample volume of > 0.1 mm 3 , without damaging the NPD anvils. These results demonstrate a large future potential of compact cells equipped with NPD anvils and enforced loading mechanism.

  13. High Energy Performance Tests of Large Volume LaBr{sub 3}:Ce Detector

    Energy Technology Data Exchange (ETDEWEB)

    Naqvi, A.A.; Gondal, M.A.; Khiari, F.Z.; Dastageer, M.A. [Department of Physics, King Fahd University of Petroleum and Minerals, Dhahran (Saudi Arabia); Maslehuddin, M.M. [Center for Engineering Research, King Fahd University of Petroleum and Minerals, Dhahran (Saudi Arabia); Al-Amoudi, O.S.B. [Department of Civil Engineering, King Fahd University of Petroleum and Minerals, Dhahran (Saudi Arabia)

    2015-07-01

    High energy prompt gamma ray tests of a large volume cylindrical 100 mm x 100 mm (height x diameter) LaBr{sub 3}:Ce detector were carried out using a portable neutron generator-based Prompt Gamma Neutron Activation Analysis (PGNAA) setup. In this study prompt gamma-rays yield were measured from water samples contaminated with toxic elements such nickel, chromium and mercury compounds with gamma ray energies up to 10 MeV. The experimental yield of prompt gamma-rays from toxic elements were compared with the results of Monte Carlo calculations. In spite of its higher intrinsic background due to its larger volume, an excellent agreement between the experimental and calculated yields of high energy gamma-rays from Ni, Cr and Hg samples has been achieved for the large volume LaBr{sub 3}:Ce detector. (authors)

  14. The impact of large tidal volume ventilation on the absorption of inhaled insulin in rabbits

    DEFF Research Database (Denmark)

    Petersen, Astrid Heide; Laursen, Torben; Ahrén, Bo

    2007-01-01

    Previous studies have shown that ventilation patterns affect absorption of inhaled compounds. Thus, the aim of this study was to investigate the effect of large tidal volume ventilation (LTVV) on the absorption of inhaled insulin in rabbits. Mechanically ventilated rabbits were given human insulin...

  15. Large volume liquid silicone injection in the upper thighs : a never ending story

    NARCIS (Netherlands)

    Hofer, SOP; Damen, A; Nicolai, JPA

    This report concerns a 26-year-old male-to-female transsexual who had received a large volume liquid silicone injection of unknown grade into her upper lateral thighs to gain female contour. She presented at our outpatient clinic 4 years after the silicone injection with complaints of pain and

  16. A New Electropositive Filter for Concentrating Enterovirus and Norovirus from Large Volumes of Water - MCEARD

    Science.gov (United States)

    The detection of enteric viruses in environmental water usually requires the concentration of viruses from large volumes of water. The 1MDS electropositive filter is commonly used for concentrating enteric viruses from water but unfortunately these filters are not cost-effective...

  17. Optimization of Large Volume Injection for Improved Detection of Polycyclic Aromatic Hydrocarbons (PAH) in Mussels

    DEFF Research Database (Denmark)

    Duedahl-Olesen, Lene; Ghorbani, Faranak

    2008-01-01

    Detection of PAH of six benzene rings is somewhat troublesome and lowering the limits of detection (LODs) for these compounds in food is necessary. For this purpose, we optimized a Programmable-Temperature-Vaporisation (PTV) injection with Large Volume Injection (LVI) with regard to the GC-MS det...

  18. Absolute activity determinations on large volume geological samples independent of self-absorption effects

    International Nuclear Information System (INIS)

    Wilson, W.E.

    1980-01-01

    This paper describes a method for measuring the absolute activity of large volume samples by γ-spectroscopy independent of self-absorption effects using Ge detectors. The method yields accurate matrix independent results at the expense of replicative counting of the unknown sample. (orig./HP)

  19. The use of cosmic muons in detecting heterogeneities in large volumes

    International Nuclear Information System (INIS)

    Grabski, V.; Reche, R.; Alfaro, R.; Belmont-Moreno, E.; Martinez-Davalos, A.; Sandoval, A.; Menchaca-Rocha, A.

    2008-01-01

    The muon intensity attenuation method to detect heterogeneities in large matter volumes is analyzed. Approximate analytical expressions to estimate the collection time and the signal to noise ratio, are proposed and validated by Monte Carlo simulations. Important parameters, including point spread function and coordinate reconstruction uncertainty are also estimated using Monte Carlo simulations

  20. Capillary gas chromatographic analysis of nerve agents using large volume injections

    NARCIS (Netherlands)

    Degenhardt, C.E.A.M.; Kientz, C.E.

    1996-01-01

    The use of large volume injections has been studied for the verification of intact organophosphorus chemical warfare agents in water samples. As the use of ethyl acetate caused severe detection problems new potential solvents were evaluated. With the developed procedure, the nerve agents sarin,

  1. SparseLeap: Efficient Empty Space Skipping for Large-Scale Volume Rendering

    KAUST Repository

    Hadwiger, Markus

    2017-08-28

    Recent advances in data acquisition produce volume data of very high resolution and large size, such as terabyte-sized microscopy volumes. These data often contain many fine and intricate structures, which pose huge challenges for volume rendering, and make it particularly important to efficiently skip empty space. This paper addresses two major challenges: (1) The complexity of large volumes containing fine structures often leads to highly fragmented space subdivisions that make empty regions hard to skip efficiently. (2) The classification of space into empty and non-empty regions changes frequently, because the user or the evaluation of an interactive query activate a different set of objects, which makes it unfeasible to pre-compute a well-adapted space subdivision. We describe the novel SparseLeap method for efficient empty space skipping in very large volumes, even around fine structures. The main performance characteristic of SparseLeap is that it moves the major cost of empty space skipping out of the ray-casting stage. We achieve this via a hybrid strategy that balances the computational load between determining empty ray segments in a rasterization (object-order) stage, and sampling non-empty volume data in the ray-casting (image-order) stage. Before ray-casting, we exploit the fast hardware rasterization of GPUs to create a ray segment list for each pixel, which identifies non-empty regions along the ray. The ray-casting stage then leaps over empty space without hierarchy traversal. Ray segment lists are created by rasterizing a set of fine-grained, view-independent bounding boxes. Frame coherence is exploited by re-using the same bounding boxes unless the set of active objects changes. We show that SparseLeap scales better to large, sparse data than standard octree empty space skipping.

  2. SparseLeap: Efficient Empty Space Skipping for Large-Scale Volume Rendering

    KAUST Repository

    Hadwiger, Markus; Al-Awami, Ali K.; Beyer, Johanna; Agus, Marco; Pfister, Hanspeter

    2017-01-01

    Recent advances in data acquisition produce volume data of very high resolution and large size, such as terabyte-sized microscopy volumes. These data often contain many fine and intricate structures, which pose huge challenges for volume rendering, and make it particularly important to efficiently skip empty space. This paper addresses two major challenges: (1) The complexity of large volumes containing fine structures often leads to highly fragmented space subdivisions that make empty regions hard to skip efficiently. (2) The classification of space into empty and non-empty regions changes frequently, because the user or the evaluation of an interactive query activate a different set of objects, which makes it unfeasible to pre-compute a well-adapted space subdivision. We describe the novel SparseLeap method for efficient empty space skipping in very large volumes, even around fine structures. The main performance characteristic of SparseLeap is that it moves the major cost of empty space skipping out of the ray-casting stage. We achieve this via a hybrid strategy that balances the computational load between determining empty ray segments in a rasterization (object-order) stage, and sampling non-empty volume data in the ray-casting (image-order) stage. Before ray-casting, we exploit the fast hardware rasterization of GPUs to create a ray segment list for each pixel, which identifies non-empty regions along the ray. The ray-casting stage then leaps over empty space without hierarchy traversal. Ray segment lists are created by rasterizing a set of fine-grained, view-independent bounding boxes. Frame coherence is exploited by re-using the same bounding boxes unless the set of active objects changes. We show that SparseLeap scales better to large, sparse data than standard octree empty space skipping.

  3. A novel technique for detection efficiency determination of HPGe

    International Nuclear Information System (INIS)

    Tayyebi, Pouneh; Abbasi Davani, Fereydoun; Tabasi, Mohsen; Afarideh, Hossein

    2017-01-01

    In this work, we present an experimental method to determine the detection efficiency of HPGe when the reference source according to the geometry of interest is not accessible. We use known activity point sources (PS) of 152 Eu, 137 Cs, 241 Am and 133 Ba to find the detection efficiency for disc source (DS) geometry. It can be assumed that a DS consists of several PS's. Mapping the detector surface by means of 137 Cs PS shows that there is radial symmetry for detection efficiency vs. energy. Each radial distance on the detector surface contains some points, which can be considered as a PS. By selecting two points in two different radii and central point, the DS efficiency is obtained. To ensure that the method is correct, we measure the activity of a known activity DS considering DS efficiency obtained by PS's. The DS comprises 137 Cs, 133 Ba and 60 Co. The relative difference between the measured and the reported activity of DS in most energies is less than 5%. - Highlights: • Exact knowledge of the detector dimension is not necessary • There is no need to have standard source according to the sample • It is a simple method that can be done at any laboratories

  4. GPU-Based 3D Cone-Beam CT Image Reconstruction for Large Data Volume

    Directory of Open Access Journals (Sweden)

    Xing Zhao

    2009-01-01

    Full Text Available Currently, 3D cone-beam CT image reconstruction speed is still a severe limitation for clinical application. The computational power of modern graphics processing units (GPUs has been harnessed to provide impressive acceleration of 3D volume image reconstruction. For extra large data volume exceeding the physical graphic memory of GPU, a straightforward compromise is to divide data volume into blocks. Different from the conventional Octree partition method, a new partition scheme is proposed in this paper. This method divides both projection data and reconstructed image volume into subsets according to geometric symmetries in circular cone-beam projection layout, and a fast reconstruction for large data volume can be implemented by packing the subsets of projection data into the RGBA channels of GPU, performing the reconstruction chunk by chunk and combining the individual results in the end. The method is evaluated by reconstructing 3D images from computer-simulation data and real micro-CT data. Our results indicate that the GPU implementation can maintain original precision and speed up the reconstruction process by 110–120 times for circular cone-beam scan, as compared to traditional CPU implementation.

  5. Comparison of experimental and theoretical efficiency of HPGe X-ray detector

    International Nuclear Information System (INIS)

    Mohanty, B.P.; Balouria, P.; Garg, M.L.; Nandi, T.K.; Mittal, V.K.; Govil, I.M.

    2008-01-01

    The low energy high purity germanium (HPGe) detectors are being increasingly used for the quantitative estimation of elements using X-ray spectrometric techniques. The softwares used for quantitative estimation normally evaluate model based efficiency of detector using manufacturer supplied detector physical parameters. The present work shows that the manufacturer supplied detector parameters for low energy HPGe detectors need to be verified by comparing model based efficiency with the experimental ones. This is particularly crucial for detectors with ion implanted P type contacts

  6. Absorption and scattering coefficient dependence of laser-Doppler flowmetry models for large tissue volumes

    International Nuclear Information System (INIS)

    Binzoni, T; Leung, T S; Ruefenacht, D; Delpy, D T

    2006-01-01

    Based on quasi-elastic scattering theory (and random walk on a lattice approach), a model of laser-Doppler flowmetry (LDF) has been derived which can be applied to measurements in large tissue volumes (e.g. when the interoptode distance is >30 mm). The model holds for a semi-infinite medium and takes into account the transport-corrected scattering coefficient and the absorption coefficient of the tissue, and the scattering coefficient of the red blood cells. The model holds for anisotropic scattering and for multiple scattering of the photons by the moving scatterers of finite size. In particular, it has also been possible to take into account the simultaneous presence of both Brownian and pure translational movements. An analytical and simplified version of the model has also been derived and its validity investigated, for the case of measurements in human skeletal muscle tissue. It is shown that at large optode spacing it is possible to use the simplified model, taking into account only a 'mean' light pathlength, to predict the blood flow related parameters. It is also demonstrated that the 'classical' blood volume parameter, derived from LDF instruments, may not represent the actual blood volume variations when the investigated tissue volume is large. The simplified model does not need knowledge of the tissue optical parameters and thus should allow the development of very simple and cost-effective LDF hardware

  7. Nonperturbative volume reduction of large-N QCD with adjoint fermions

    International Nuclear Information System (INIS)

    Bringoltz, Barak; Sharpe, Stephen R.

    2009-01-01

    We use nonperturbative lattice techniques to study the volume-reduced 'Eguchi-Kawai' version of four-dimensional large-N QCD with a single adjoint Dirac fermion. We explore the phase diagram of this single-site theory in the space of quark mass and gauge coupling using Wilson fermions for a number of colors in the range 8≤N≤15. Our evidence suggests that these values of N are large enough to determine the nature of the phase diagram for N→∞. We identify the region in the parameter space where the (Z N ) 4 center symmetry is intact. According to previous theoretical work using the orbifolding paradigm, and assuming that translation invariance is not spontaneously broken in the infinite-volume theory, in this region volume reduction holds: the single-site and infinite-volume theories become equivalent when N→∞. We find strong evidence that this region includes both light and heavy quarks (with masses that are at the cutoff scale), and our results are consistent with this region extending toward the continuum limit. We also compare the action density and the eigenvalue density of the overlap Dirac operator in the fundamental representation with those obtained in large-N pure-gauge theory.

  8. Large-Scale Multi-Resolution Representations for Accurate Interactive Image and Volume Operations

    KAUST Repository

    Sicat, Ronell B.

    2015-11-25

    The resolutions of acquired image and volume data are ever increasing. However, the resolutions of commodity display devices remain limited. This leads to an increasing gap between data and display resolutions. To bridge this gap, the standard approach is to employ output-sensitive operations on multi-resolution data representations. Output-sensitive operations facilitate interactive applications since their required computations are proportional only to the size of the data that is visible, i.e., the output, and not the full size of the input. Multi-resolution representations, such as image mipmaps, and volume octrees, are crucial in providing these operations direct access to any subset of the data at any resolution corresponding to the output. Despite its widespread use, this standard approach has some shortcomings in three important application areas, namely non-linear image operations, multi-resolution volume rendering, and large-scale image exploration. This dissertation presents new multi-resolution representations for large-scale images and volumes that address these shortcomings. Standard multi-resolution representations require low-pass pre-filtering for anti- aliasing. However, linear pre-filters do not commute with non-linear operations. This becomes problematic when applying non-linear operations directly to any coarse resolution levels in standard representations. Particularly, this leads to inaccurate output when applying non-linear image operations, e.g., color mapping and detail-aware filters, to multi-resolution images. Similarly, in multi-resolution volume rendering, this leads to inconsistency artifacts which manifest as erroneous differences in rendering outputs across resolution levels. To address these issues, we introduce the sparse pdf maps and sparse pdf volumes representations for large-scale images and volumes, respectively. These representations sparsely encode continuous probability density functions (pdfs) of multi-resolution pixel

  9. Effect, Feasibility, and Clinical Relevance of Cell Enrichment in Large Volume Fat Grafting

    DEFF Research Database (Denmark)

    Rasmussen, Bo Sonnich; Lykke Sørensen, Celine; Vester-Glowinski, Peter Viktor

    2017-01-01

    Large volume fat grafting is limited by unpredictable volume loss; therefore, methods of improving graft retention have been developed. Fat graft enrichment with either stromal vascular fraction (SVF) cells or adipose tissue-derived stem/stromal cells (ASCs) has been investigated in several animal...... and human studies, and significantly improved graft retention has been reported. Improvement of graft retention and the feasibility of these techniques are equally important in evaluating the clinical relevance of cell enrichment. We conducted a systematic search of PubMed to identify studies on fat graft...... enrichment that used either SVF cells or ASCs, and only studies reporting volume assessment were included. A total of 38 articles (15 human and 23 animal) were included to investigate the effects of cell enrichment on graft retention as well as the feasibility and clinical relevance of cell-enriched fat...

  10. Toxicity Profile With a Large Prostate Volume After External Beam Radiotherapy for Localized Prostate Cancer

    International Nuclear Information System (INIS)

    Pinkawa, Michael; Fischedick, Karin; Asadpour, Branka; Gagel, Bernd; Piroth, Marc D.; Nussen, Sandra; Eble, Michael J.

    2008-01-01

    Purpose: To assess the impact of prostate volume on health-related quality of life (HRQOL) before and at different intervals after radiotherapy for prostate cancer. Methods and Materials: A group of 204 patients was surveyed prospectively before (Time A), at the last day (Time B), 2 months after (Time C), and 16 months (median) after (Time D) radiotherapy, with a validated questionnaire (Expanded Prostate Cancer Index Composite). The group was divided into subgroups with a small (11-43 cm 3 ) and a large (44-151 cm 3 ) prostate volume. Results: Patients with large prostates presented with lower urinary bother scores (median 79 vs. 89; p = 0.01) before treatment. Urinary function/bother scores for patients with large prostates decreased significantly compared to patients with small prostates due to irritative/obstructive symptoms only at Time B (pain with urination more than once daily in 48% vs. 18%; p 3 vs. 47 cm 3 ; p < 0.01). Conclusions: Patients with a large prostate volume have a great risk of irritative/obstructive symptoms (particularly dysuria) in the acute radiotherapy phase. These symptoms recover rapidly and do not influence long-term HRQOL

  11. HPGe detectors long time behaviour in high-resolution γ spectrometry

    International Nuclear Information System (INIS)

    Sajo-Bohus, L.; Rosso, D.; Sajo Castelli, A.M.; Napoli, D.R.; Fioretto, E.; Menegazzo, R.; Barros, H.; Ur, C.A.; Palacios, D.; Liendo, J.

    2011-01-01

    A large set of data on long term performance of n-type HPGe detectors used in GASP, EUROBALL and CLARA γ spectrometers, as well as environmental measurements have been collected over two decades. In this paper a detailed statistical analysis of this data is given and detector long term behaviour is provided to the scientific community. We include failure, failure mode, repair frequency, repair outcome and its influence in the energy efficiency and energy resolution. A remarkable result is that the life span distribution is exponential. A detector's failure is a memory-less process, where a previous failure does not influence the upcoming one. Repaired spectrometers result in high reliability with deep implications in the management of large scale high-resolution gamma spectrometry related projects. Findings show that on average, detectors initial counting efficiency is slightly lower (∼2%) than that reported by the manufacturers and the repair process (including annealing) does not affect significantly the energy efficiency, even after a long period of use. Repaired detector energy resolution statistics show that the probability, that a repaired detector will be at least as good as it was originally, is more than 3/4.

  12. A New Virtual Point Detector Concept for a HPGe detector

    International Nuclear Information System (INIS)

    Byun, Jong In; Yun, Ju Yong

    2009-01-01

    For last several decades, the radiation measurement and radioactivity analysis techniques using gamma detectors have been well established. Especially , the study about the detection efficiency has been done as an important part of gamma spectrometry. The detection efficiency depends strongly on source-to-detector distance. The detection efficiency with source-to-detector distance can be expressed by a complex function of geometry and physical characteristics of gamma detectors. In order to simplify the relation, a virtual point detector concept was introduced by Notea. Recently, further studies concerning the virtual point detector have been performed. In previous other works the virtual point detector has been considered as a fictitious point existing behind the detector end cap. However the virtual point detector position for the front and side of voluminous detectors might be different due to different effective central axis of them. In order to more accurately define the relation, therefore, we should consider the virtual point detector for the front as well as side and off-center of the detector. The aim of this study is to accurately define the relation between the detection efficiency and source-to-detector distance with the virtual point detector. This paper demonstrates the method to situate the virtual point detectors for a HPGe detector. The new virtual point detector concept was introduced for three area of the detector and its characteristics also were demonstrated by using Monte Carlo Simulation method. We found that the detector has three virtual point detectors except for its rear area. This shows that we should consider the virtual point detectors for each area when applying the concept to radiation measurement. This concept can be applied to the accurate geometric simplification for the detector and radioactive sources.

  13. Application of PHOTON simulation software on calibration of HPGe detectors

    Energy Technology Data Exchange (ETDEWEB)

    Nikolic, J., E-mail: jnikolic@vinca.rs [University of Belgrade Institute for Nuclear Sciences Vinča, Mike Petrovica Alasa 12-16, 11001 Belgrade (Serbia); Puzovic, J. [University of Belgrade Faculty of Physics, Studentski trg 6, 11000 Belgrade (Serbia); Todorovic, D.; Rajacic, M. [University of Belgrade Institute for Nuclear Sciences Vinča, Mike Petrovica Alasa 12-16, 11001 Belgrade (Serbia)

    2015-11-01

    One of the major difficulties in gamma spectrometry of voluminous environmental samples is the efficiency calibration of the detectors used for the measurement. The direct measurement of different calibration sources, containing isolated γ-ray emitters within the energy range of interest, and subsequent fitting to a parametric function, is the most accurate and at the same time most complicated and time consuming method of efficiency calibration. Many other methods are developed in time, some of them using Monte Carlo simulation. One of such methods is a dedicated and user-friendly program PHOTON, developed to simulate the passage of photons through different media with different geometries. This program was used for efficiency calibration of three HPGe detectors, readily used in Laboratory for Environment and Radiation Protection of the Institute for Nuclear Sciences Vinca, Belgrade, Serbia. The simulation produced the spectral response of the detectors for fixed energy and for different sample geometries and matrices. Thus obtained efficiencies were compared to the values obtained by the measurement of the secondary reference materials and to the results obtained by GEANT4 simulation, in order to establish whether the simulated values agree with the experimental ones. To further analyze the results, a realistic measurement of the materials provided by the IAEA within different interlaboratory proficiency tests, was performed. The activities obtained using simulated efficiencies were compared to the reference values provided by the organizer. A good agreement in the mid energy section of the spectrum was obtained, while for low energies the lack of some parameters in the simulation libraries proved to produce unacceptable discrepancies.

  14. Intraoperative ventilation: incidence and risk factors for receiving large tidal volumes during general anesthesia

    Directory of Open Access Journals (Sweden)

    Fernandez-Bustamante Ana

    2011-11-01

    Full Text Available Abstract Background There is a growing concern of the potential injurious role of ventilatory over-distention in patients without lung injury. No formal guidelines exist for intraoperative ventilation settings, but the use of tidal volumes (VT under 10 mL/kg predicted body weight (PBW has been recommended in healthy patients. We explored the incidence and risk factors for receiving large tidal volumes (VT > 10 mL/kg PBW. Methods We performed a cross-sectional analysis of our prospectively collected perioperative electronic database for current intraoperative ventilation practices and risk factors for receiving large tidal volumes (VT > 10 mL/kg PBW. We included all adults undergoing prolonged (≥ 4 h elective abdominal surgery and collected demographic, preoperative (comorbidities, intraoperative (i.e. ventilatory settings, fluid administration and postoperative (outcomes information. We compared patients receiving exhaled tidal volumes > 10 mL/kg PBW with those that received 8-10 or Results Ventilatory settings were non-uniform in the 429 adults included in the analysis. 17.5% of all patients received VT > 10 mL/kg PBW. 34.0% of all obese patients (body mass index, BMI, ≥ 30, 51% of all patients with a height T > 10 mL/kg PBW. Conclusions Ventilation with VT > 10 mL/kg PBW is still common, although poor correlation with PBW suggests it may be unintentional. BMI ≥ 30, female gender and height

  15. Geophysics Under Pressure: Large-Volume Presses Versus the Diamond-Anvil Cell

    Science.gov (United States)

    Hazen, R. M.

    2002-05-01

    Prior to 1970, the legacy of Harvard physicist Percy Bridgman dominated high-pressure geophysics. Massive presses with large-volume devices, including piston-cylinder, opposed-anvil, and multi-anvil configurations, were widely used in both science and industry to achieve a range of crustal and upper mantle temperatures and pressures. George Kennedy of UCLA was a particularly influential advocate of large-volume apparatus for geophysical research prior to his death in 1980. The high-pressure scene began to change in 1959 with the invention of the diamond-anvil cell, which was designed simultaneously and independently by John Jamieson at the University of Chicago and Alvin Van Valkenburg at the National Bureau of Standards in Washington, DC. The compact, inexpensive diamond cell achieved record static pressures and had the advantage of optical access to the high-pressure environment. Nevertheless, members of the geophysical community, who favored the substantial sample volumes, geothermally relevant temperature range, and satisfying bulk of large-volume presses, initially viewed the diamond cell with indifference or even contempt. Several factors led to a gradual shift in emphasis from large-volume presses to diamond-anvil cells in geophysical research during the 1960s and 1970s. These factors include (1) their relatively low cost at time of fiscal restraint, (2) Alvin Van Valkenburg's new position as a Program Director at the National Science Foundation in 1964 (when George Kennedy's proposal for a Nation High-Pressure Laboratory was rejected), (3) the development of lasers and micro-analytical spectroscopic techniques suitable for analyzing samples in a diamond cell, and (4) the attainment of record pressures (e.g., 100 GPa in 1975 by Mao and Bell at the Geophysical Laboratory). Today, a more balanced collaborative approach has been adopted by the geophysics and mineral physics community. Many high-pressure laboratories operate a new generation of less expensive

  16. Assembly, operation and disassembly manual for the Battelle Large Volume Water Sampler (BLVWS)

    International Nuclear Information System (INIS)

    Thomas, V.W.; Campbell, R.M.

    1984-12-01

    Assembly, operation and disassembly of the Battelle Large Volume Water Sampler (BLVWS) are described in detail. Step by step instructions of assembly, general operation and disassembly are provided to allow an operator completely unfamiliar with the sampler to successfully apply the BLVWS to his research sampling needs. The sampler permits concentration of both particulate and dissolved radionuclides from large volumes of ocean and fresh water. The water sample passes through a filtration section for particle removal then through sorption or ion exchange beds where species of interest are removed. The sampler components which contact the water being sampled are constructed of polyvinylchloride (PVC). The sampler has been successfully applied to many sampling needs over the past fifteen years. 9 references, 8 figures

  17. Measurement of Atmospheric Neutrino Oscillations with Very Large Volume Neutrino Telescopes

    Directory of Open Access Journals (Sweden)

    J. P. Yáñez

    2015-01-01

    Full Text Available Neutrino oscillations have been probed during the last few decades using multiple neutrino sources and experimental set-ups. In the recent years, very large volume neutrino telescopes have started contributing to the field. First ANTARES and then IceCube have relied on large and sparsely instrumented volumes to observe atmospheric neutrinos for combinations of baselines and energies inaccessible to other experiments. Using this advantage, the latest result from IceCube starts approaching the precision of other established technologies and is paving the way for future detectors, such as ORCA and PINGU. These new projects seek to provide better measurements of neutrino oscillation parameters and eventually determine the neutrino mass ordering. The results from running experiments and the potential from proposed projects are discussed in this review, emphasizing the experimental challenges involved in the measurements.

  18. Management of Large Volumes of Waste Arising in a Nuclear or Radiological Emergency

    International Nuclear Information System (INIS)

    2017-10-01

    This publication, prepared in light of the IAEA Action Plan on Nuclear Safety developed after the accident at the Fukushima Daiichi nuclear power plant, addresses the management of large volumes of radioactive waste arising in a nuclear or radiological emergency, as part of overall emergency preparedness. The management of large volumes of waste will be one of many efforts to be dealt with to allow recovery of affected areas, to support return of evacuated or relocated populations and preparations for normal social and economic activities, and/or to mitigate additional environmental impacts. The publication is intended to be of use to national planners and policy makers, facility and programme managers, and other professionals responsible for developing and implementing national plans and strategies to manage radioactive waste arising from nuclear or radiological emergencies.

  19. F-term stabilization of odd axions in LARGE volume scenario

    International Nuclear Information System (INIS)

    Gao, Xin; Shukla, Pramod

    2014-01-01

    In the context of the LARGE volume scenario, stabilization of axionic moduli is revisited. This includes both even and odd axions with their scalar potential being generated by F-term contributions via various tree-level and non-perturbative effects like fluxed E3-brane instantons and fluxed poly-instantons. In all the cases, we estimate the decay constants and masses of the axions involved

  20. Numerical simulation of seismic wave propagation from land-excited large volume air-gun source

    Science.gov (United States)

    Cao, W.; Zhang, W.

    2017-12-01

    The land-excited large volume air-gun source can be used to study regional underground structures and to detect temporal velocity changes. The air-gun source is characterized by rich low frequency energy (from bubble oscillation, 2-8Hz) and high repeatability. It can be excited in rivers, reservoirs or man-made pool. Numerical simulation of the seismic wave propagation from the air-gun source helps to understand the energy partitioning and characteristics of the waveform records at stations. However, the effective energy recorded at a distance station is from the process of bubble oscillation, which can not be approximated by a single point source. We propose a method to simulate the seismic wave propagation from the land-excited large volume air-gun source by finite difference method. The process can be divided into three parts: bubble oscillation and source coupling, solid-fluid coupling and the propagation in the solid medium. For the first part, the wavelet of the bubble oscillation can be simulated by bubble model. We use wave injection method combining the bubble wavelet with elastic wave equation to achieve the source coupling. Then, the solid-fluid boundary condition is implemented along the water bottom. And the last part is the seismic wave propagation in the solid medium, which can be readily implemented by the finite difference method. Our method can get accuracy waveform of land-excited large volume air-gun source. Based on the above forward modeling technology, we analysis the effect of the excited P wave and the energy of converted S wave due to different water shapes. We study two land-excited large volume air-gun fields, one is Binchuan in Yunnan, and the other is Hutubi in Xinjiang. The station in Binchuan, Yunnan is located in a large irregular reservoir, the waveform records have a clear S wave. Nevertheless, the station in Hutubi, Xinjiang is located in a small man-made pool, the waveform records have very weak S wave. Better understanding of

  1. First results on material identification and imaging with a large-volume muon tomography prototype

    Energy Technology Data Exchange (ETDEWEB)

    Pesente, S. [INFN Sezione di Padova, via Marzolo 8, 35131 Padova (Italy); Vanini, S. [University of Padova and INFN Sezione di Padova, via Marzolo 8, 35131 Padova (Italy)], E-mail: sara.vanini@pd.infn.it; Benettoni, M. [INFN Sezione di Padova, via Marzolo 8, 35131 Padova (Italy); Bonomi, G. [University of Brescia, via Branze 38, 25123 Brescia and INFN Sezione di Pavia, via Bassi 6, 27100 Pavia (Italy); Calvini, P. [University of Genova and INFN Sezione di Genova, via Dodecaneso 33, 16146 Genova (Italy); Checchia, P.; Conti, E.; Gonella, F.; Nebbia, G. [INFN Sezione di Padova, via Marzolo 8, 35131 Padova (Italy); Squarcia, S. [University of Genova and INFN Sezione di Genova, via Dodecaneso 33, 16146 Genova (Italy); Viesti, G. [University of Padova and INFN Sezione di Padova, via Marzolo 8, 35131 Padova (Italy); Zenoni, A. [University of Brescia, via Branze 38, 25123 Brescia and INFN Sezione di Pavia, via Bassi 6, 27100 Pavia (Italy); Zumerle, G. [University of Padova and INFN Sezione di Padova, via Marzolo 8, 35131 Padova (Italy)

    2009-06-11

    The muon tomography technique, based on the Multiple Coulomb Scattering of cosmic ray muons, has been proposed recently as a tool to perform non-destructive assays of large-volume objects without any radiation hazard. In this paper we discuss experimental results obtained with a scanning system prototype, assembled using two large-area CMS Muon Barrel drift chambers. The capability of the apparatus to produce 3D images of objects and to classify them according to their density is presented. We show that the absorption of low-momentum muons in the scanned objects produces an underestimate of their scattering density, making the discrimination of materials heavier than lead more difficult.

  2. First results on material identification and imaging with a large-volume muon tomography prototype

    Energy Technology Data Exchange (ETDEWEB)

    Viesti, G. [Dipartimento di Fisica, Universita di Padova, via Marzolo 8, I-35131 Padova (Italy); Pesente, S.; Benettoni, M.; Checchia, P.; Conti, E.; Gonella, F.; Nebbia, G. [INFN, Sez. di Padova, Via Marzolo 8, I-35131 Padova (Italy); Vanini, S.; Viesti, G.; Zumerle, G. [Dip. di Fisica G. Galilei, Universita di Padova, I-35131 Padova (Italy); INFN, Sez. di Padova, Via Marzolo 8, I-35131 Padova (Italy); Bonomi, G.; Zenoni, A. [Universita di Brescia, I-25133 Brescia (Italy); INFN, Sez. di Pavia, Via Valotti 9, I-25133 Brescia (Italy); Calvini, P.; Squarcia, S. [Dip. di Fisica, Universita di Genova, Genova (Italy); INFN, Sez. di Genova, Via Dodecaneso 33, I-16146 Genova (Italy)

    2009-07-01

    The muon tomography technique, based on the multiple Coulomb scattering of cosmic ray muons, has been proposed recently as a tool to perform non-destructive assays of large volume objects without any radiation hazard. In this paper we present the experimental results obtained with a scanning system prototype, assembled using two large area CMS Muon Barrel drift chambers. The imaging capability of the apparatus is shown, and the possibility to discriminate among different materials is discussed in a specific case of detecting lead objects inside a metal matrix. This specific case is dictated by a need in safely handling scrap metal cargoes in the steel industry. (authors)

  3. State-of-the-Art in GPU-Based Large-Scale Volume Visualization

    KAUST Repository

    Beyer, Johanna

    2015-05-01

    This survey gives an overview of the current state of the art in GPU techniques for interactive large-scale volume visualization. Modern techniques in this field have brought about a sea change in how interactive visualization and analysis of giga-, tera- and petabytes of volume data can be enabled on GPUs. In addition to combining the parallel processing power of GPUs with out-of-core methods and data streaming, a major enabler for interactivity is making both the computational and the visualization effort proportional to the amount and resolution of data that is actually visible on screen, i.e. \\'output-sensitive\\' algorithms and system designs. This leads to recent output-sensitive approaches that are \\'ray-guided\\', \\'visualization-driven\\' or \\'display-aware\\'. In this survey, we focus on these characteristics and propose a new categorization of GPU-based large-scale volume visualization techniques based on the notions of actual output-resolution visibility and the current working set of volume bricks-the current subset of data that is minimally required to produce an output image of the desired display resolution. Furthermore, we discuss the differences and similarities of different rendering and data traversal strategies in volume rendering by putting them into a common context-the notion of address translation. For our purposes here, we view parallel (distributed) visualization using clusters as an orthogonal set of techniques that we do not discuss in detail but that can be used in conjunction with what we present in this survey. © 2015 The Eurographics Association and John Wiley & Sons Ltd.

  4. State-of-the-Art in GPU-Based Large-Scale Volume Visualization

    KAUST Repository

    Beyer, Johanna; Hadwiger, Markus; Pfister, Hanspeter

    2015-01-01

    This survey gives an overview of the current state of the art in GPU techniques for interactive large-scale volume visualization. Modern techniques in this field have brought about a sea change in how interactive visualization and analysis of giga-, tera- and petabytes of volume data can be enabled on GPUs. In addition to combining the parallel processing power of GPUs with out-of-core methods and data streaming, a major enabler for interactivity is making both the computational and the visualization effort proportional to the amount and resolution of data that is actually visible on screen, i.e. 'output-sensitive' algorithms and system designs. This leads to recent output-sensitive approaches that are 'ray-guided', 'visualization-driven' or 'display-aware'. In this survey, we focus on these characteristics and propose a new categorization of GPU-based large-scale volume visualization techniques based on the notions of actual output-resolution visibility and the current working set of volume bricks-the current subset of data that is minimally required to produce an output image of the desired display resolution. Furthermore, we discuss the differences and similarities of different rendering and data traversal strategies in volume rendering by putting them into a common context-the notion of address translation. For our purposes here, we view parallel (distributed) visualization using clusters as an orthogonal set of techniques that we do not discuss in detail but that can be used in conjunction with what we present in this survey. © 2015 The Eurographics Association and John Wiley & Sons Ltd.

  5. Novel regenerative large-volume immobilized enzyme reactor: preparation, characterization and application.

    Science.gov (United States)

    Ruan, Guihua; Wei, Meiping; Chen, Zhengyi; Su, Rihui; Du, Fuyou; Zheng, Yanjie

    2014-09-15

    A novel large-volume immobilized enzyme reactor (IMER) on small column was prepared with organic-inorganic hybrid silica particles and applied for fast (10 min) and oriented digestion of protein. At first, a thin enzyme support layer was formed in the bottom of the small column by polymerization with α-methacrylic acid and dimethacrylate. After that, amino SiO2 particles was prepared by the sol-gel method with tetraethoxysilane and 3-aminopropyltriethoxysilane. Subsequently, the amino SiO2 particles were activated by glutaraldehyde for covalent immobilization of trypsin. Digestive capability of large-volume IMER for proteins was investigated by using bovine serum albumin (BSA), cytochrome c (Cyt-c) as model proteins. Results showed that although the sequence coverage of the BSA (20%) and Cyt-c (19%) was low, the large-volume IMER could produce peptides with stable specific sequence at 101-105, 156-160, 205-209, 212-218, 229-232, 257-263 and 473-451 of the amino sequence of BSA when digesting 1mg/mL BSA. Eight of common peptides were observed during each of the ten runs of large-volume IMER. Besides, the IMER could be easily regenerated by reactivating with GA and cross-linking with trypsin after breaking the -C=N- bond by 0.01 M HCl. The sequence coverage of BSA from regenerated IMER increased to 25% comparing the non-regenerated IMER (17%). 14 common peptides. accounting for 87.5% of first use of IMER, were produced both with IMER and regenerated IMER. When the IMER was applied for ginkgo albumin digestion, the sequence coverage of two main proteins of ginkgo, ginnacin and legumin, was 56% and 55%, respectively. (Reviewer 2) Above all, the fast and selective digestion property of the large-volume IMER indicated that the regenerative IMER could be tentatively used for the production of potential bioactive peptides and the study of oriented protein digestion. Copyright © 2014 Elsevier B.V. All rights reserved.

  6. Comparison of HPGe detector response data for low energy photons using MCNP, EGS, and its codes

    International Nuclear Information System (INIS)

    Kim, Soon Young; Kim, Jong Kyung

    1995-01-01

    In this study, the photopeak efficiency, K α and K β escape fractions of HPGe detector(100mm 2 X 10mm) are calculated and tabulated as a function of incident X-ray energies from 12 to 60keV in 2-keV increments. Compton, elastic, and penetration fractions are not tabulated from this work since they are negligible amounts in this energy range. The results calculated from this work are compared with earlier Monte Carlo results which had been carried out by Chin-Tu Chen et al.. From the comparison, it is found that the results calculated from each code show a large difference when the incident photon energy approaches to 12keV as compared with energy ranges from 50 to 60keV. In X-ray dosimetry and diagnostic radiology, it is essential to have accurate knowledge of X-ray spectra for studies of patient dose and image quality. Being X-ray spectra measured with a detection system, some distortions due to the incomplete absorption of primary photon or escape before interacting with the detector which have finite dimension can take place

  7. Large-volume paracentesis with indwelling peritoneal catheter and albumin infusion: a community hospital study

    Directory of Open Access Journals (Sweden)

    Daniel K. Martin

    2016-10-01

    Full Text Available Background: The management of ascites can be problematic. This is especially true in patients with diuretic refractory ascites who develop a tense abdomen. This often results in hypotension and decreased venous return with resulting renal failure. In this paper, we further examine the risks and benefits of utilizing an indwelling peritoneal catheter to remove large-volume ascites over a 72-h period while maintaining intravascular volume and preventing renal failure. Methods: We retrospectively reviewed charts and identified 36 consecutive patients undergoing continuous large-volume paracentesis with an indwelling peritoneal catheter. At the time of drain placement, no patients had signs or laboratory parameters suggestive of spontaneous bacterial peritonitis. The patients underwent ascitic fluid removal through an indwelling peritoneal catheter and were supported with scheduled albumin throughout the duration. The catheter was used to remove up to 3 L every 8 h for a maximum of 72 h. Regular laboratory and ascitic fluid testing was performed. All patients had a clinical follow-up within 3 months after the drain placement. Results: An average of 16.5 L was removed over the 72-h time frame of indwelling peritoneal catheter maintenance. The albumin infusion utilized correlated to 12 mg/L removed. The average creatinine trend improved in a statistically significant manner from 1.37 on the day of admission to 1.21 on the day of drain removal. No patients developed renal failure during the hospital course. There were no documented episodes of neutrocytic ascites or bacterial peritonitis throughout the study review. Conclusion: Large-volume peritoneal drainage with an indwelling peritoneal catheter is safe and effective for patients with tense ascites. Concomitant albumin infusion allows for maintenance of renal function, and no increase in infectious complications was noted.

  8. Enhanced FIB-SEM systems for large-volume 3D imaging

    Science.gov (United States)

    Xu, C Shan; Hayworth, Kenneth J; Lu, Zhiyuan; Grob, Patricia; Hassan, Ahmed M; García-Cerdán, José G; Niyogi, Krishna K; Nogales, Eva; Weinberg, Richard J; Hess, Harald F

    2017-01-01

    Focused Ion Beam Scanning Electron Microscopy (FIB-SEM) can automatically generate 3D images with superior z-axis resolution, yielding data that needs minimal image registration and related post-processing. Obstacles blocking wider adoption of FIB-SEM include slow imaging speed and lack of long-term system stability, which caps the maximum possible acquisition volume. Here, we present techniques that accelerate image acquisition while greatly improving FIB-SEM reliability, allowing the system to operate for months and generating continuously imaged volumes > 106 µm3. These volumes are large enough for connectomics, where the excellent z resolution can help in tracing of small neuronal processes and accelerate the tedious and time-consuming human proofreading effort. Even higher resolution can be achieved on smaller volumes. We present example data sets from mammalian neural tissue, Drosophila brain, and Chlamydomonas reinhardtii to illustrate the power of this novel high-resolution technique to address questions in both connectomics and cell biology. DOI: http://dx.doi.org/10.7554/eLife.25916.001 PMID:28500755

  9. Computational characterization of HPGe detectors usable for a wide variety of source geometries by using Monte Carlo simulation and a multi-objective evolutionary algorithm

    Energy Technology Data Exchange (ETDEWEB)

    Guerra, J.G., E-mail: jglezg2002@gmail.es [Departamento de Física, Universidad de Las Palmas de Gran Canaria, 35001 Las Palmas de Gran Canaria (Spain); Rubiano, J.G. [Departamento de Física, Universidad de Las Palmas de Gran Canaria, 35001 Las Palmas de Gran Canaria (Spain); Instituto Universitario de Estudios Ambientales y Recursos Naturales, Universidad de Las Palmas de Gran Canaria, 35001 Las Palmas de Gran Canaria (Spain); Winter, G. [Instituto Universitario de Sistemas Inteligentes y Aplicaciones Numéricas en la Ingeniería, Universidad de Las Palmas de Gran Canaria, 35001 Las Palmas de Gran Canaria (Spain); Guerra, A.G.; Alonso, H.; Arnedo, M.A.; Tejera, A.; Martel, P. [Departamento de Física, Universidad de Las Palmas de Gran Canaria, 35001 Las Palmas de Gran Canaria (Spain); Instituto Universitario de Estudios Ambientales y Recursos Naturales, Universidad de Las Palmas de Gran Canaria, 35001 Las Palmas de Gran Canaria (Spain); Bolivar, J.P. [Departamento de Física Aplicada, Universidad de Huelva, 21071 Huelva (Spain)

    2017-06-21

    In this work, we have developed a computational methodology for characterizing HPGe detectors by implementing in parallel a multi-objective evolutionary algorithm, together with a Monte Carlo simulation code. The evolutionary algorithm is used for searching the geometrical parameters of a model of detector by minimizing the differences between the efficiencies calculated by Monte Carlo simulation and two reference sets of Full Energy Peak Efficiencies (FEPEs) corresponding to two given sample geometries, a beaker of small diameter laid over the detector window and a beaker of large capacity which wrap the detector. This methodology is a generalization of a previously published work, which was limited to beakers placed over the window of the detector with a diameter equal or smaller than the crystal diameter, so that the crystal mount cap (which surround the lateral surface of the crystal), was not considered in the detector model. The generalization has been accomplished not only by including such a mount cap in the model, but also using multi-objective optimization instead of mono-objective, with the aim of building a model sufficiently accurate for a wider variety of beakers commonly used for the measurement of environmental samples by gamma spectrometry, like for instance, Marinellis, Petris, or any other beaker with a diameter larger than the crystal diameter, for which part of the detected radiation have to pass through the mount cap. The proposed methodology has been applied to an HPGe XtRa detector, providing a model of detector which has been successfully verificated for different source-detector geometries and materials and experimentally validated using CRMs. - Highlights: • A computational method for characterizing HPGe detectors has been generalized. • The new version is usable for a wider range of sample geometries. • It starts from reference FEPEs obtained through a standard calibration procedure. • A model of an HPGe XtRa detector has been

  10. Computational characterization of HPGe detectors usable for a wide variety of source geometries by using Monte Carlo simulation and a multi-objective evolutionary algorithm

    International Nuclear Information System (INIS)

    Guerra, J.G.; Rubiano, J.G.; Winter, G.; Guerra, A.G.; Alonso, H.; Arnedo, M.A.; Tejera, A.; Martel, P.; Bolivar, J.P.

    2017-01-01

    In this work, we have developed a computational methodology for characterizing HPGe detectors by implementing in parallel a multi-objective evolutionary algorithm, together with a Monte Carlo simulation code. The evolutionary algorithm is used for searching the geometrical parameters of a model of detector by minimizing the differences between the efficiencies calculated by Monte Carlo simulation and two reference sets of Full Energy Peak Efficiencies (FEPEs) corresponding to two given sample geometries, a beaker of small diameter laid over the detector window and a beaker of large capacity which wrap the detector. This methodology is a generalization of a previously published work, which was limited to beakers placed over the window of the detector with a diameter equal or smaller than the crystal diameter, so that the crystal mount cap (which surround the lateral surface of the crystal), was not considered in the detector model. The generalization has been accomplished not only by including such a mount cap in the model, but also using multi-objective optimization instead of mono-objective, with the aim of building a model sufficiently accurate for a wider variety of beakers commonly used for the measurement of environmental samples by gamma spectrometry, like for instance, Marinellis, Petris, or any other beaker with a diameter larger than the crystal diameter, for which part of the detected radiation have to pass through the mount cap. The proposed methodology has been applied to an HPGe XtRa detector, providing a model of detector which has been successfully verificated for different source-detector geometries and materials and experimentally validated using CRMs. - Highlights: • A computational method for characterizing HPGe detectors has been generalized. • The new version is usable for a wider range of sample geometries. • It starts from reference FEPEs obtained through a standard calibration procedure. • A model of an HPGe XtRa detector has been

  11. Operation of bare HPGe detectors in LAr/LN{sub 2} for the GERDA experiment

    Energy Technology Data Exchange (ETDEWEB)

    Heider, M Barnabe; Chkvorets, O; Schoenert, S [MPI fuer Kernphysik, Heidelberg (Germany); Cattadori, C [INFN-Milano Bicocca, Milano (Italy); Vacri, A di [INFN-LNGS, L' Aquila (Italy); Gusev, K; Shirchenko, M [Russian Research Center Kurchatov Institute, Moscow, Russia and JINR, Dubna (Russian Federation)], E-mail: assunta.divacri@lngs.infn.it

    2008-11-01

    GERDA is designed to search for 0{nu}{beta}{beta}-decay of {sup 76}Ge using high purity germanium detectors (HPGe), enriched ({approx} 85%) in {sup 76}Ge, directly immersed in LAr which acts both as shield against {gamma} radiation and as cooling medium. The cryostat is located in a stainless steel water tank providing an additional shield against external background. The GERDA experiment aims at a background (b) {approx}<10{sup -3} cts/(kg-y-keV) and energy resolution (FWHM) {<=} 4 keV at Q{sub {beta}}{sub {beta}} = 2039 keV. GERDA experiment is foreseen to proceed in two phases. For Phase I, eight reprocessed enriched HPGe detectors from the past HdM [C Balysh et al., Phys. Rev. D 66 (1997) 54] and IGEX [C E Aalseth et al., Phys. of Atomic Nuclei 63 (2000) 1225] experiments ({approx} 18 kg) and six reprocessed natural HPGe detectors ({approx} 15 kg) from the Genius Test-Facility [H V Klapdor et al., HIM A 481 (2002) 149] will be deployed in strings. GERDA aims at b {approx}< 10{sup -2} cts/(kg{center_dot}keV{center_dot}y). With an exposure of {approx} 15 kg{center_dot}y of {sup 76}Ge and resolution {approx} 3.6 keV, the sensitivity on the half-life will be T{sup 0{nu}}{sub 1/2} 3 {center_dot} 10{sup 25} y (90 % C.L.) corresponding to m{sub ee} < 270 meV [V A Rodin et al., Nucl. Phys. A 766 (2006) 107]. In Phase II, new diodes, able to discriminate between single- and multi-site events, will be added ({approx} 20 kg of {sup 76}Ge with intrinsic b {approx} 10{sup -2} cts/(kg{center_dot}keV{center_dot}y). With an exposure of {approx} 120 kg{center_dot}y, it is expected T{sup 0{nu}}{sub 1/2} > 1.5 {center_dot} 10{sup 26} y (90% C.L.) corresponding to m{sub ee} < 110 meV [V A Rodin et al., Nucl. Phys. A 766 (2006) 107]. Three natural p-type HPGe prototypes (different passivation layer designs) are available in the GERDA underground facility at LNGS to investigate the effect of the detector assembly (low-mass low-activity holder), of the handling procedure and of the

  12. A self-sampling method to obtain large volumes of undiluted cervicovaginal secretions.

    Science.gov (United States)

    Boskey, Elizabeth R; Moench, Thomas R; Hees, Paul S; Cone, Richard A

    2003-02-01

    Studies of vaginal physiology and pathophysiology sometime require larger volumes of undiluted cervicovaginal secretions than can be obtained by current methods. A convenient method for self-sampling these secretions outside a clinical setting can facilitate such studies of reproductive health. The goal was to develop a vaginal self-sampling method for collecting large volumes of undiluted cervicovaginal secretions. A menstrual collection device (the Instead cup) was inserted briefly into the vagina to collect secretions that were then retrieved from the cup by centrifugation in a 50-ml conical tube. All 16 women asked to perform this procedure found it feasible and acceptable. Among 27 samples, an average of 0.5 g of secretions (range, 0.1-1.5 g) was collected. This is a rapid and convenient self-sampling method for obtaining relatively large volumes of undiluted cervicovaginal secretions. It should prove suitable for a wide range of assays, including those involving sexually transmitted diseases, microbicides, vaginal physiology, immunology, and pathophysiology.

  13. Hierarchical imaging: a new concept for targeted imaging of large volumes from cells to tissues.

    Science.gov (United States)

    Wacker, Irene; Spomer, Waldemar; Hofmann, Andreas; Thaler, Marlene; Hillmer, Stefan; Gengenbach, Ulrich; Schröder, Rasmus R

    2016-12-12

    Imaging large volumes such as entire cells or small model organisms at nanoscale resolution seemed an unrealistic, rather tedious task so far. Now, technical advances have lead to several electron microscopy (EM) large volume imaging techniques. One is array tomography, where ribbons of ultrathin serial sections are deposited on solid substrates like silicon wafers or glass coverslips. To ensure reliable retrieval of multiple ribbons from the boat of a diamond knife we introduce a substrate holder with 7 axes of translation or rotation specifically designed for that purpose. With this device we are able to deposit hundreds of sections in an ordered way in an area of 22 × 22 mm, the size of a coverslip. Imaging such arrays in a standard wide field fluorescence microscope produces reconstructions with 200 nm lateral resolution and 100 nm (the section thickness) resolution in z. By hierarchical imaging cascades in the scanning electron microscope (SEM), using a new software platform, we can address volumes from single cells to complete organs. In our first example, a cell population isolated from zebrafish spleen, we characterize different cell types according to their organelle inventory by segmenting 3D reconstructions of complete cells imaged with nanoscale resolution. In addition, by screening large numbers of cells at decreased resolution we can define the percentage at which different cell types are present in our preparation. With the second example, the root tip of cress, we illustrate how combining information from intermediate resolution data with high resolution data from selected regions of interest can drastically reduce the amount of data that has to be recorded. By imaging only the interesting parts of a sample considerably less data need to be stored, handled and eventually analysed. Our custom-designed substrate holder allows reproducible generation of section libraries, which can then be imaged in a hierarchical way. We demonstrate, that EM

  14. A Novel Technique for Endovascular Removal of Large Volume Right Atrial Tumor Thrombus

    Energy Technology Data Exchange (ETDEWEB)

    Nickel, Barbara, E-mail: nickel.ba@gmail.com [US Teleradiology and Quantum Medical Radiology Group (United States); McClure, Timothy, E-mail: tmcclure@gmail.com; Moriarty, John, E-mail: jmoriarty@mednet.ucla.edu [UCLA Medical Center, Department of Interventional Radiology (United States)

    2015-08-15

    Venous thromboembolic disease is a significant cause of morbidity and mortality, particularly in the setting of large volume pulmonary embolism. Thrombolytic therapy has been shown to be a successful treatment modality; however, its use somewhat limited due to the risk of hemorrhage and potential for distal embolization in the setting of large mobile thrombi. In patients where either thrombolysis is contraindicated or unsuccessful, and conventional therapies prove inadequate, surgical thrombectomy may be considered. We present a case of percutaneous endovascular extraction of a large mobile mass extending from the inferior vena cava into the right atrium using the Angiovac device, a venovenous bypass system designed for high-volume aspiration of undesired endovascular material. Standard endovascular methods for removal of cancer-associated thrombus, such as catheter-directed lysis, maceration, and exclusion, may prove inadequate in the setting of underlying tumor thrombus. Where conventional endovascular methods either fail or are unsuitable, endovascular thrombectomy with the Angiovac device may be a useful and safe minimally invasive alternative to open resection.

  15. A Novel Technique for Endovascular Removal of Large Volume Right Atrial Tumor Thrombus

    International Nuclear Information System (INIS)

    Nickel, Barbara; McClure, Timothy; Moriarty, John

    2015-01-01

    Venous thromboembolic disease is a significant cause of morbidity and mortality, particularly in the setting of large volume pulmonary embolism. Thrombolytic therapy has been shown to be a successful treatment modality; however, its use somewhat limited due to the risk of hemorrhage and potential for distal embolization in the setting of large mobile thrombi. In patients where either thrombolysis is contraindicated or unsuccessful, and conventional therapies prove inadequate, surgical thrombectomy may be considered. We present a case of percutaneous endovascular extraction of a large mobile mass extending from the inferior vena cava into the right atrium using the Angiovac device, a venovenous bypass system designed for high-volume aspiration of undesired endovascular material. Standard endovascular methods for removal of cancer-associated thrombus, such as catheter-directed lysis, maceration, and exclusion, may prove inadequate in the setting of underlying tumor thrombus. Where conventional endovascular methods either fail or are unsuitable, endovascular thrombectomy with the Angiovac device may be a useful and safe minimally invasive alternative to open resection

  16. Measurement of β-decay end point energy with planar HPGe detector

    Energy Technology Data Exchange (ETDEWEB)

    Bhattacharjee, T., E-mail: btumpa@vecc.gov.in [Physics Group, Variable Energy Cyclotron Centre, Kolkata 700 064 (India); Pandit, Deepak [Physics Group, Variable Energy Cyclotron Centre, Kolkata 700 064 (India); Das, S.K. [RCD-BARC, Variable Energy Cyclotron Centre, Kolkata 700 064 (India); Chowdhury, A.; Das, P. [Physics Group, Variable Energy Cyclotron Centre, Kolkata 700 064 (India); Banerjee, D. [RCD-BARC, Variable Energy Cyclotron Centre, Kolkata 700 064 (India); Saha, A.; Mukhopadhyay, S.; Pal, S.; Banerjee, S.R. [Physics Group, Variable Energy Cyclotron Centre, Kolkata 700 064 (India)

    2014-12-11

    The β–γ coincidence measurement has been performed with a segmented planar Hyper-Pure Germanium (HPGe) detector and a single coaxial HPGe detector to determine the end point energies of nuclear β-decays. The experimental end point energies have been determined for some of the known β-decays in {sup 106}Rh→{sup 106}Pd. The end point energies corresponding to three weak branches in {sup 106}Rh→{sup 106}Pd decay have been measured for the first time. The γ ray and β particle responses for the planar HPGe detector were simulated using the Monte Carlo based code GEANT3. The experimentally obtained β spectra were successfully reproduced with the simulation.

  17. Open loop control of filament heating power supply for large volume plasma device

    Energy Technology Data Exchange (ETDEWEB)

    Sugandhi, R., E-mail: ritesh@ipr.res.in [Institute for Plasma Research, Gandhinagar, Gujarat 382428 (India); Homi Bhabha National Institute, Mumbai 400094 (India); Srivastava, P.K.; Sanyasi, A.K. [Homi Bhabha National Institute, Mumbai 400094 (India); Srivastav, Prabhakar [Institute for Plasma Research, Gandhinagar, Gujarat 382428 (India); Homi Bhabha National Institute, Mumbai 400094 (India); Awasthi, L.M., E-mail: kushagra.lalit@gmail.com [Institute for Plasma Research, Gandhinagar, Gujarat 382428 (India); Homi Bhabha National Institute, Mumbai 400094 (India); Mattoo, S.K. [Homi Bhabha National Institute, Mumbai 400094 (India)

    2017-02-15

    A power supply (20 V, 10 kA) for powering the filamentary cathode has been procured, interfaced and integrated with the centralized control system of Large Volume Plasma Device (LVPD). Software interface has been developed on the standard Modbus RTU communication protocol. It facilitates the dashboard for configuration, on line status monitoring, alarm management, data acquisition, synchronization and controls. It has been tested for stable operation of the power supply for the operational capabilities. The paper highlights the motivation, interface description, implementation and results obtained.

  18. Open loop control of filament heating power supply for large volume plasma device

    International Nuclear Information System (INIS)

    Sugandhi, R.; Srivastava, P.K.; Sanyasi, A.K.; Srivastav, Prabhakar; Awasthi, L.M.; Mattoo, S.K.

    2017-01-01

    A power supply (20 V, 10 kA) for powering the filamentary cathode has been procured, interfaced and integrated with the centralized control system of Large Volume Plasma Device (LVPD). Software interface has been developed on the standard Modbus RTU communication protocol. It facilitates the dashboard for configuration, on line status monitoring, alarm management, data acquisition, synchronization and controls. It has been tested for stable operation of the power supply for the operational capabilities. The paper highlights the motivation, interface description, implementation and results obtained.

  19. Complex Security System for Premises Under Conditions of Large Volume of Passenger Traffic

    Directory of Open Access Journals (Sweden)

    Yakubov Vladimir

    2016-01-01

    Full Text Available Subsystems of the design of a complex security system for premises under conditions of large volume of passenger traffic are considered. These subsystems provide video- and thermal imaging control, radio wave tomography, and gas analysis. Simultaneous application of all examined variants will essentially increase the probability of timely prevention of dangerous situations with the probability of false alarm as low as possible. It is important that finally, this will provide protection of population and will facilitate the work of intelligence services.

  20. Fan-beam scanning laser optical computed tomography for large volume dosimetry

    Science.gov (United States)

    Dekker, K. H.; Battista, J. J.; Jordan, K. J.

    2017-05-01

    A prototype scanning-laser fan beam optical CT scanner is reported which is capable of high resolution, large volume dosimetry with reasonable scan time. An acylindrical, asymmetric aquarium design is presented which serves to 1) generate parallel-beam scan geometry, 2) focus light towards a small acceptance angle detector, and 3) avoid interference fringe-related artifacts. Preliminary experiments with uniform solution phantoms (11 and 15 cm diameter) and finger phantoms (13.5 mm diameter FEP tubing) demonstrate that the design allows accurate optical CT imaging, with optical CT measurements agreeing within 3% of independent Beer-Lambert law calculations.

  1. Mass anomalous dimension of Adjoint QCD at large N from twisted volume reduction

    CERN Document Server

    Pérez, Margarita García; Keegan, Liam; Okawa, Masanori

    2015-01-01

    In this work we consider the $SU(N)$ gauge theory with two Dirac fermions in the adjoint representation, in the limit of large $N$. In this limit the infinite-volume physics of this model can be studied by means of the corresponding twisted reduced model defined on a single site lattice. Making use of this strategy we study the reduced model for various values of $N$ up to 289. By analyzing the eigenvalue distribution of the adjoint Dirac operator we test the conformality of the theory and extract the corresponding mass anomalous dimension.

  2. Mass anomalous dimension of adjoint QCD at large N from twisted volume reduction

    Energy Technology Data Exchange (ETDEWEB)

    Pérez, Margarita García [Instituto de Física Teórica UAM-CSIC, Nicolás Cabrera 13-15, Universidad Autónoma de Madrid,E-28049-Madrid (Spain); González-Arroyo, Antonio [Instituto de Física Teórica UAM-CSIC, Nicolás Cabrera 13-15, Universidad Autónoma de Madrid,E-28049-Madrid (Spain); Departamento de Física Teórica, C-XI, Universidad Autónoma de Madrid,E-28049-Madrid (Spain); Keegan, Liam [PH-TH, CERN,CH-1211 Geneva 23 (Switzerland); Okawa, Masanori [Graduate School of Science, Hiroshima University,Higashi-Hiroshima, Hiroshima 739-8526 (Japan); Core of Research for the Energetic Universe, Hiroshima University,Higashi-Hiroshima, Hiroshima 739-8526 (Japan)

    2015-08-07

    In this work we consider the SU(N) gauge theory with two Dirac fermions in the adjoint representation, in the limit of large N. In this limit the infinite-volume physics of this model can be studied by means of the corresponding twisted reduced model defined on a single site lattice. Making use of this strategy we study the reduced model for various values of N up to 289. By analyzing the eigenvalue distribution of the adjoint Dirac operator we test the conformality of the theory and extract the corresponding mass anomalous dimension.

  3. Biological intrusion barriers for large-volume waste-disposal sites

    International Nuclear Information System (INIS)

    Hakonson, T.E.; Cline, J.F.; Rickard, W.H.

    1982-01-01

    intrusion of plants and animals into shallow land burial sites with subsequent mobilization of toxic and radiotoxic materials has occured. Based on recent pathway modeling studies, such intrusions can contribute to the dose received by man. This paper describes past work on developing biological intrusion barrier systems for application to large volume waste site stabilization. State-of-the-art concepts employing rock and chemical barriers are discussed relative to long term serviceability and cost of application. The interaction of bio-intrusion barrier systems with other processes affecting trench cover stability are discussed to ensure that trench cover designs minimize the potential dose to man. 3 figures, 6 tables

  4. Characteristics of the NE-213 large-volume neutron counters for muon catalyzed fusion investigation

    International Nuclear Information System (INIS)

    Bystritsky, V.M.; Wozniak, J.; Zinov, V.G.

    1984-01-01

    The Monte-Carlo method was used to establish the properties and feasibility of a large-volume NE-213 scin illator as an efficient neutron detector. The recoil proton spectra, calculated efficiencies for different detection thresholds and scintillator sizes are presented for the neutron energy up to 15 MeV. The time characteristics, e. g., time resolution, are discussed. It is also shown that no strong influence of light attenuation by the scintilla or itself on calculated efficiencies is observed, when gamma-calibration technique is used. The detector vol me of approximately 100 l is suggested for application in investigations of μ-atom and μ-molecular processes

  5. Fan-beam scanning laser optical computed tomography for large volume dosimetry

    International Nuclear Information System (INIS)

    Dekker, K H; Battista, J J; Jordan, K J

    2017-01-01

    A prototype scanning-laser fan beam optical CT scanner is reported which is capable of high resolution, large volume dosimetry with reasonable scan time. An acylindrical, asymmetric aquarium design is presented which serves to 1) generate parallel-beam scan geometry, 2) focus light towards a small acceptance angle detector, and 3) avoid interference fringe-related artifacts. Preliminary experiments with uniform solution phantoms (11 and 15 cm diameter) and finger phantoms (13.5 mm diameter FEP tubing) demonstrate that the design allows accurate optical CT imaging, with optical CT measurements agreeing within 3% of independent Beer-Lambert law calculations. (paper)

  6. Electro-mechanical probe positioning system for large volume plasma device

    Science.gov (United States)

    Sanyasi, A. K.; Sugandhi, R.; Srivastava, P. K.; Srivastav, Prabhakar; Awasthi, L. M.

    2018-05-01

    An automated electro-mechanical system for the positioning of plasma diagnostics has been designed and implemented in a Large Volume Plasma Device (LVPD). The system consists of 12 electro-mechanical assemblies, which are orchestrated using the Modbus communication protocol on 4-wire RS485 communications to meet the experimental requirements. Each assembly has a lead screw-based mechanical structure, Wilson feed-through-based vacuum interface, bipolar stepper motor, micro-controller-based stepper drive, and optical encoder for online positioning correction of probes. The novelty of the system lies in the orchestration of multiple drives on a single interface, fabrication and installation of the system for a large experimental device like the LVPD, in-house developed software, and adopted architectural practices. The paper discusses the design, description of hardware and software interfaces, and performance results in LVPD.

  7. SDSS Log Viewer: visual exploratory analysis of large-volume SQL log data

    Science.gov (United States)

    Zhang, Jian; Chen, Chaomei; Vogeley, Michael S.; Pan, Danny; Thakar, Ani; Raddick, Jordan

    2012-01-01

    User-generated Structured Query Language (SQL) queries are a rich source of information for database analysts, information scientists, and the end users of databases. In this study a group of scientists in astronomy and computer and information scientists work together to analyze a large volume of SQL log data generated by users of the Sloan Digital Sky Survey (SDSS) data archive in order to better understand users' data seeking behavior. While statistical analysis of such logs is useful at aggregated levels, efficiently exploring specific patterns of queries is often a challenging task due to the typically large volume of the data, multivariate features, and data requirements specified in SQL queries. To enable and facilitate effective and efficient exploration of the SDSS log data, we designed an interactive visualization tool, called the SDSS Log Viewer, which integrates time series visualization, text visualization, and dynamic query techniques. We describe two analysis scenarios of visual exploration of SDSS log data, including understanding unusually high daily query traffic and modeling the types of data seeking behaviors of massive query generators. The two scenarios demonstrate that the SDSS Log Viewer provides a novel and potentially valuable approach to support these targeted tasks.

  8. A retrospective analysis of complications of large volume liposuction; local perspective from a third world country

    International Nuclear Information System (INIS)

    Arshad, S.M.; Latif, S.; Altaf, H.N.

    2017-01-01

    This study was aimed at evaluating the complications that occurred in patients undergoing large volume liposuction and to see if there was a correlation between amount of aspirate and the rate of complications. Methodology: A detailed history, complete physical examination, BMI, and anthropometric measurements were documented for all patients. All patients under went liposuction using tumescent technique under general anesthesia in Yusra General Hospital. Patients were discharged home after 24 to 48 hours. Pressure garments were advised for 6 weeks and were called for weekly follow up for 6 weeks. Pressure garments were advised for 6 weeks. Complications were documented. SPSS version 20 was used for analysis of data. Results: Out of 217 patients, 163 (75%) were female and 54 male. Mean age was 37.1 SD+-6.7 years. Bruising and seroma were most common complications; 4.1% and 2.3%, respectively. The incidence of infection was 0.9%. One patient had over-correction and four patients (1.8%) had under-correction. Significant blood loss was encountered in one patient. Two patients (0.9%) had pulmonary embolism and 2(0.9%) suffered from necrotizing fasciitis. None of our patients undergoing large volume liposuction had fat embolism and there was no mortality. Conclusion: Careful patient selection and strict adherence to guidelines can ensure a good outcome and can minimize risk of complications. Both physicians and patients should be educated to have realistic expectations to avoid complications and improve patient safety. (author)

  9. Broadband frequency ECR ion source concepts with large resonant plasma volumes

    International Nuclear Information System (INIS)

    Alton, G.D.

    1995-01-01

    New techniques are proposed for enhancing the performances of ECR ion sources. The techniques are based on the use of high-power, variable-frequency, multiple-discrete-frequency, or broadband microwave radiation, derived from standard TWT technology, to effect large resonant ''volume'' ECR sources. The creation of a large ECR plasma ''volume'' permits coupling of more power into the plasma, resulting in the heating of a much larger electron population to higher energies, the effect of which is to produce higher charge state distributions and much higher intensities within a particular charge state than possible in present forms of the ECR ion source. If successful, these developments could significantly impact future accelerator designs and accelerator-based, heavy-ion-research programs by providing multiply-charged ion beams with the energies and intensities required for nuclear physics research from existing ECR ion sources. The methods described in this article can be used to retrofit any ECR ion source predicated on B-minimum plasma confinement techniques

  10. Colloids Versus Albumin in Large Volume Paracentesis to Prevent Circulatory Dysfunction: Evidence-based Case Report.

    Science.gov (United States)

    Widjaja, Felix F; Khairan, Paramita; Kamelia, Telly; Hasan, Irsan

    2016-04-01

    Large volume paracentesis may cause paracentesis induced circulatory dysfunction (PICD). Albumin is recommended to prevent this abnormality. Meanwhile, the price of albumin is too expensive and there should be another alternative that may prevent PICD. This report aimed to compare albumin to colloids in preventing PICD. Search strategy was done using PubMed, Scopus, Proquest, dan Academic Health Complete from EBSCO with keywords of "ascites", "albumin", "colloid", "dextran", "hydroxyethyl starch", "gelatin", and "paracentesis induced circulatory dysfunction". Articles was limited to randomized clinical trial and meta-analysis with clinical question of "In hepatic cirrhotic patient undergone large volume paracentesis, whether colloids were similar to albumin to prevent PICD". We found one meta-analysis and four randomized clinical trials (RCT). A meta analysis showed that albumin was still superior of which odds ratio 0.34 (0.23-0.51). Three RCTs showed the same results and one RCT showed albumin was not superior than colloids. We conclude that colloids could not constitute albumin to prevent PICD, but colloids still have a role in patient who undergone paracentesis less than five liters.

  11. Capillary gas chromatographic analysis of nerve agents using large volume injections. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Deinum, T.; Nieuwenhuy, C.

    1994-11-01

    The procedure developed at TNO-Prins Maurits Laboratory (TNO-PML) for the verification of intact organophosphorus chemical warfare agents in water samples was improved. The last step in this procedure, the laborious and non-reproducible transfer of an ethyl acetate extract onto a Tenax-adsorption tube followed by thermal desorption of the Tenax-tube, was replaced by large volume injection of the extract onto a capillary gas chromatographic system. The parameters controlling the injection of a large volume of an extract (200 ul) were investigated and optimized. As ethyl acetate caused severe problems, potential new solvents were evaluated. With the improved procedure, the nerve agents sarin, tabun, soman, diisopropyl fluorophosphate (DFP) and VX could be determined in freshly prepared water samples at pg/ml (ppt) levels. The fate of the nerve agents under study in water at two pH`s (4.8 and 6) was investigated. For VX, the pH should be adjusted before extraction. Moreover, it is worthwhile to acidify water samples to diminish hydrolysis.

  12. Large volume recycling of oceanic lithosphere over short time scales: geochemical constraints from the Caribbean Large Igneous Province

    Science.gov (United States)

    Hauff, F.; Hoernle, K.; Tilton, G.; Graham, D. W.; Kerr, A. C.

    2000-01-01

    isochron diagrams suggests that the age of separation of enriched and depleted components from the depleted MORB source mantle could have been ≤500 Ma before CLIP formation and interpreted to reflect the recycling time of the CLIP source. Mantle plume heads may provide a mechanism for transporting large volumes of possibly young recycled oceanic lithosphere residing in the lower mantle back into the shallow MORB source mantle.

  13. Large electrically induced height and volume changes in poly(3,4- ethylenedioxythiophene) /poly(styrenesulfonate) thin films

    NARCIS (Netherlands)

    Charrier, D.S.H.; Janssen, R.A.J.; Kemerink, M.

    2010-01-01

    We demonstrate large, partly reversible height and volume changes of thin films of poly(3,4-ethylenedioxythiophene)/poly(styrenesulfonate) (PEDOT:PSS) on the anode of interdigitating gold electrodes under ambient conditions by applying an electrical bias. The height and volume changes were monitored

  14. System of large transport containers for waste from dismantling light water and gas-cooled nuclear reactors. Volume 2

    International Nuclear Information System (INIS)

    Price, M.S.T.; Lafontaine, I.

    1985-01-01

    The purpose of this volume is to assess the means of transportation of decommissioning wastes, costs of transport, radiological detriment attributable to transport and develops conceptual designs of large transport containers. The document ends with Conclusions and Recommendations

  15. Quantitative microanalysis in the analytical electronmicroscope using an HPGe-x ray detector

    International Nuclear Information System (INIS)

    Grogger, W.

    1994-01-01

    Energy dispersive x-ray spectrometry (EDX) is a routine method for determining the chemical composition of a sample in the analytical electronmicroscope. Since some years high purity germanium x-ray detectors (HPGe) are commercially available for use in EDX. This new type of detector offers some advantages over the commonly used Si (Li) detector: better energy resolution, better detector efficiency for high energy lines (> 30 keV) and better stability against exterior influences. For quantitative analysis one needs sensitivity factors (k-factors), which correlate the measured intensity to the concentration of a specific element. These k-factors can be calculated or determined experimentally. For a precise quantitative analysis of light elements measured k-factors are absolutely necessary. In this study k-factors were measured with an HPGe detector using standards. The accuracy of the k-factors was proved using some examples of practical relevance. Additionally some special features of the HPGe detector were examined, which lead to a better understanding of EDX spectrometry using an HPGe detector (escape lines, icing of the detector, artifacts). (author)

  16. New approach to calculate the true-coincidence effect of HpGe detector

    Energy Technology Data Exchange (ETDEWEB)

    Alnour, I. A., E-mail: aaibrahim3@live.utm.my, E-mail: ibrahim.elnour@yahoo.com [Department of Physics, Faculty of Pure and Applied Science, International University of Africa, 12223 Khartoum (Sudan); Wagiran, H. [Department of Physics, Faculty of Science, Universiti Teknologi Malaysia, 81310 UTM Skudai,Johor (Malaysia); Ibrahim, N. [Faculty of Defence Science and Technology, National Defence University of Malaysia, Kem Sungai Besi, 57000 Kuala Lumpur (Malaysia); Hamzah, S.; Elias, M. S. [Malaysia Nuclear Agency (MNA), Bangi, 43000 Kajang, Selangor D.E. (Malaysia); Siong, W. B. [Chemistry Department, Faculty of Resource Science & Technology, Universiti Malaysia Sarawak, 94300 Kota Samarahan, Sarawak (Malaysia)

    2016-01-22

    The corrections for true-coincidence effects in HpGe detector are important, especially at low source-to-detector distances. This work established an approach to calculate the true-coincidence effects experimentally for HpGe detectors of type Canberra GC3018 and Ortec GEM25-76-XLB-C, which are in operation at neutron activation analysis lab in Malaysian Nuclear Agency (NM). The correction for true-coincidence effects was performed close to detector at distances 2 and 5 cm using {sup 57}Co, {sup 60}Co, {sup 133}Ba and {sup 137}Cs as standard point sources. The correction factors were ranged between 0.93-1.10 at 2 cm and 0.97-1.00 at 5 cm for Canberra HpGe detector; whereas for Ortec HpGe detector ranged between 0.92-1.13 and 0.95-100 at 2 and 5 cm respectively. The change in efficiency calibration curve of the detector at 2 and 5 cm after correction was found to be less than 1%. Moreover, the polynomial parameters functions were simulated through a computer program, MATLAB in order to find an accurate fit to the experimental data points.

  17. Study of the performance of HPGe detectors operating in very high magnetic fields

    International Nuclear Information System (INIS)

    Agnello, M.; Botta, E.; Bressani, T.; Bruschi, M.; Bufalino, S.; De Napoli, M.; Feliciello, A.; Fontana, A.; Giacobbe, B.; Lavezzi, L.; Raciti, G.; Rapisarda, E.; Rotondi, A.; Sbarra, C.; Sfienti, C.; Zoccoli, A.

    2009-01-01

    A new generation of high-resolution hypernuclear γ-spectroscopy experiments using high-purity germanium (HPGe) detectors is presently designed for the FINUDA spectrometer at DAΦNE, the Frascati Φ-factory, and for PANDA, the p-p-bar hadron spectrometer at the future FAIR facility. In both spectrometers the HPGe detectors have to be operated in strong magnetic fields. In this paper we report on a series of measurements performed on a HPGe detector inserted in a magnetic field of intensity up to 2.5 T, the highest ever reached for operations with a HPGe, and with different orientations of the detector's axis with respect to field direction. A significant worsening of the energy resolution was found, but with a moderate loss of the efficiency. The most relevant features of the peak shapes, described by bi-Gaussian functions, are parametrized in terms of field intensity and energy: this allows to correct the spectra measured in magnetic field and to recover the energy resolution almost completely.

  18. A detailed investigation of interactions within the shielding to HPGe detector response using MCNP code

    Energy Technology Data Exchange (ETDEWEB)

    Thanh, Tran Thien; Tao, Chau Van; Loan, Truong Thi Hong; Nhon, Mai Van; Chuong, Huynh Dinh; Au, Bui Hai [Vietnam National Univ., Ho Chi Minh City (Viet Nam). Dept. of Nuclear Physics

    2012-12-15

    The accuracy of the coincidence-summing corrections in gamma spectrometry depends on the total efficiency calibration that is hardly obtained over the whole energy as the required experimental conditions are not easily attained. Monte Carlo simulations using MCNP5 code was performed in order to estimate the affect of the shielding to total efficiency. The effect of HPGe response are also shown. (orig.)

  19. Safe total corporal contouring with large-volume liposuction for the obese patient.

    Science.gov (United States)

    Dhami, Lakshyajit D; Agarwal, Meenakshi

    2006-01-01

    The advent of the tumescent technique in 1987 allowed for safe total corporal contouring as an ambulatory, single-session megaliposuction with the patient under regional anesthesia supplemented by local anesthetic only in selected areas. Safety and aesthetic issues define large-volume liposuction as having a 5,000-ml aspirate, mega-volume liposuction as having an 8,000-ml aspirate, and giganto-volume liposuction as having an aspirate of 12,000 ml or more. Clinically, a total volume comprising 5,000 ml of fat and wetting solution aspirated during the procedure qualifies for megaliposuction/large-volume liposuction. Between September 2000 and August 2005, 470 cases of liposuction were managed. In 296 (63%) of the 470 cases, the total volume of aspirate exceeded 5 l (range, 5,000-22,000 ml). Concurrent limited or total-block lipectomy was performed in 70 of 296 cases (23.6%). Regional anesthesia with conscious sedation was preferred, except where liposuction targeted areas above the subcostal region (the upper trunk, lateral chest, gynecomastia, breast, arms, and face), or when the patient so desired. Tumescent infiltration was achieved with hypotonic lactated Ringer's solution, adrenalin, triamcinalone, and hyalase in all cases during the last one year of the series. This approach has clinically shown less tissue edema in the postoperative period than with conventional physiologic saline used in place of the Ringer's lactate solution. The amount injected varied from 1,000 to 8,000 ml depending on the size, site, and area. Local anesthetic was included only for the terminal portion of the tumescent mixture, wherever the subcostal regions were infiltrated. The aspirate was restricted to the unstained white/yellow fat, and the amount of fat aspirated did not have any bearing on the amount of solution infiltrated. There were no major complications, and no blood transfusions were administered. The hospital stay ranged from 8 to 24 h for both liposuction and liposuction

  20. Large volume serial section tomography by Xe Plasma FIB dual beam microscopy.

    Science.gov (United States)

    Burnett, T L; Kelley, R; Winiarski, B; Contreras, L; Daly, M; Gholinia, A; Burke, M G; Withers, P J

    2016-02-01

    Ga(+) Focused Ion Beam-Scanning Electron Microscopes (FIB-SEM) have revolutionised the level of microstructural information that can be recovered in 3D by block face serial section tomography (SST), as well as enabling the site-specific removal of smaller regions for subsequent transmission electron microscope (TEM) examination. However, Ga(+) FIB material removal rates limit the volumes and depths that can be probed to dimensions in the tens of microns range. Emerging Xe(+) Plasma Focused Ion Beam-Scanning Electron Microscope (PFIB-SEM) systems promise faster removal rates. Here we examine the potential of the method for large volume serial section tomography as applied to bainitic steel and WC-Co hard metals. Our studies demonstrate that with careful control of milling parameters precise automated serial sectioning can be achieved with low levels of milling artefacts at removal rates some 60× faster. Volumes that are hundreds of microns in dimension have been collected using fully automated SST routines in feasible timescales (<24h) showing good grain orientation contrast and capturing microstructural features at the tens of nanometres to the tens of microns scale. Accompanying electron back scattered diffraction (EBSD) maps show high indexing rates suggesting low levels of surface damage. Further, under high current Ga(+) FIB milling WC-Co is prone to amorphisation of WC surface layers and phase transformation of the Co phase, neither of which have been observed at PFIB currents as high as 60nA at 30kV. Xe(+) PFIB dual beam microscopes promise to radically extend our capability for 3D tomography, 3D EDX, 3D EBSD as well as correlative tomography. Copyright © 2015 The Authors. Published by Elsevier B.V. All rights reserved.

  1. Effect, Feasibility, and Clinical Relevance of Cell Enrichment in Large Volume Fat Grafting: A Systematic Review.

    Science.gov (United States)

    Rasmussen, Bo Sonnich; Lykke Sørensen, Celine; Vester-Glowinski, Peter Viktor; Herly, Mikkel; Trojahn Kølle, Stig-Frederik; Fischer-Nielsen, Anne; Drzewiecki, Krzysztof Tadeusz

    2017-07-01

    Large volume fat grafting is limited by unpredictable volume loss; therefore, methods of improving graft retention have been developed. Fat graft enrichment with either stromal vascular fraction (SVF) cells or adipose tissue-derived stem/stromal cells (ASCs) has been investigated in several animal and human studies, and significantly improved graft retention has been reported. Improvement of graft retention and the feasibility of these techniques are equally important in evaluating the clinical relevance of cell enrichment. We conducted a systematic search of PubMed to identify studies on fat graft enrichment that used either SVF cells or ASCs, and only studies reporting volume assessment were included. A total of 38 articles (15 human and 23 animal) were included to investigate the effects of cell enrichment on graft retention as well as the feasibility and clinical relevance of cell-enriched fat grafting. Improvements in graft retention, the SVF to fat (SVF:fat) ratio, and the ASC concentration used for enrichment were emphasized. We proposed an increased retention rate greater than 1.5-fold relative to nonenriched grafts and a maximum SVF:fat ratio of 1:1 as the thresholds for clinical relevance and feasibility, respectively. Nine studies fulfilled these criteria, whereof 6 used ASCs for enrichment. We found no convincing evidence of a clinically relevant effect of SVF enrichment in humans. ASC enrichment has shown promising results in enhancing graft retention, but additional clinical trials are needed to substantiate this claim and also determine the optimal concentration of SVF cells/ASCs for enrichment. 4. © 2017 The American Society for Aesthetic Plastic Surgery, Inc. Reprints and permission: journals.permissions@oup.com.

  2. Volume changes of extremely large and giant intracranial aneurysms after treatment with flow diverter stents

    Energy Technology Data Exchange (ETDEWEB)

    Carneiro, Angelo; Byrne, James V. [ohn Radcliffe Hospital, Oxford Neurovascular and Neuroradiology Research Unit, Nuffield Department of Surgical Sciences, Oxford (United Kingdom); Rane, Neil; Kueker, Wilhelm; Cellerini, Martino; Corkill, Rufus [John Radcliffe Hospital, Department of Neuroradiology, Oxford (United Kingdom)

    2014-01-15

    This study assessed volume changes of unruptured large and giant aneurysms (greatest diameter >20 mm) after treatment with flow diverter (FD) stents. Clinical audit of the cases treated in a single institution, over a 5-year period. Demographic and clinical data were retrospectively collected from the hospital records. Aneurysm volumes were measured by manual outlining at sequential slices using computerised tomography (CT) or magnetic resonance (MR) angiography data. The audit included eight patients (seven females) with eight aneurysms. Four aneurysms involved the cavernous segment of the internal carotid artery (ICA), three the supraclinoid ICA and one the basilar artery. Seven patients presented with signs and symptoms of mass effect and one with seizures. All but one aneurysm was treated with a single FD stent; six aneurysms were also coiled (either before or simultaneously with FD placement). Minimum follow-up time was 6 months (mean 20 months). At follow-up, three aneurysms decreased in size, three were unchanged and two increased. Both aneurysms that increased in size showed persistent endosaccular flow at follow-up MR; in one case, failure was attributed to suboptimal position of the stent; in the other case, it was attributed to persistence of a side branch originating from the aneurysm (similar to the endoleak phenomenon of aortic aneurysms). At follow-up, five aneurysms were completely occluded; none of these increased in volume. Complete occlusion of the aneurysms leads, in most cases, to its shrinkage. In cases of late aneurysm growth or regrowth, consideration should be given to possible endoleak as the cause. (orig.)

  3. Tumor Volume Decrease via Feeder Occlusion for Treating a Large, Firm Trigone Meningioma.

    Science.gov (United States)

    Nakashima, Takuma; Hatano, Norikazu; Kanamori, Fumiaki; Muraoka, Shinsuke; Kawabata, Teppei; Takasu, Syuntaro; Watanabe, Tadashi; Kojima, Takao; Nagatani, Tetsuya; Seki, Yukio

    2018-01-01

    Trigone meningiomas are considered a surgical challenge, as they tend to be considerably large and hypervascularized at the time of presentation. We experienced a case of a large and very hard trigone meningioma that was effectively treated using initial microsurgical feeder occlusion followed by surgery in stages. A 19-year-old woman who presented with loss of consciousness was referred to our hospital for surgical treatment of a brain tumor. Radiological findings were compatible with a left ventricular trigone meningioma extending laterally in proximity to the Sylvian fissure. At initial surgery using the transsylvian approach, main feeders originating from the anterior and lateral posterior choroidal arteries were occluded at the inferior horn; however, only a small section of the tumor could initially be removed because of its firmness. Over time, feeder occlusion resulted in tumor necrosis and a 20% decrease in its diameter; the mass effect was alleviated within 1 year. The residual meningioma was then totally excised in staged surgical procedures after resection became more feasible owing to ischemia-induced partial softening of the tumor. When a trigone meningioma is large and very hard, initial microsurgical feeder occlusion in the inferior horn can be a safe and effective option, and can lead to necrosis, volume decrease, and partial softening of the residual tumor to allow for its staged surgical excision.

  4. A large volume uniform plasma generator for the experiments of electromagnetic wave propagation in plasma

    International Nuclear Information System (INIS)

    Yang Min; Li Xiaoping; Xie Kai; Liu Donglin; Liu Yanming

    2013-01-01

    A large volume uniform plasma generator is proposed for the experiments of electromagnetic (EM) wave propagation in plasma, to reproduce a “black out” phenomenon with long duration in an environment of the ordinary laboratory. The plasma generator achieves a controllable approximate uniform plasma in volume of 260 mm× 260 mm× 180 mm without the magnetic confinement. The plasma is produced by the glow discharge, and the special discharge structure is built to bring a steady approximate uniform plasma environment in the electromagnetic wave propagation path without any other barriers. In addition, the electron density and luminosity distributions of plasma under different discharge conditions were diagnosed and experimentally investigated. Both the electron density and the plasma uniformity are directly proportional to the input power and in roughly reverse proportion to the gas pressure in the chamber. Furthermore, the experiments of electromagnetic wave propagation in plasma are conducted in this plasma generator. Blackout phenomena at GPS signal are observed under this system and the measured attenuation curve is of reasonable agreement with the theoretical one, which suggests the effectiveness of the proposed method.

  5. Rugged Large Volume Injection for Sensitive Capillary LC-MS Environmental Monitoring

    Directory of Open Access Journals (Sweden)

    Hanne Roberg-Larsen

    2017-08-01

    Full Text Available A rugged and high throughput capillary column (cLC LC-MS switching platform using large volume injection and on-line automatic filtration and filter back-flush (AFFL solid phase extraction (SPE for analysis of environmental water samples with minimal sample preparation is presented. Although narrow columns and on-line sample preparation are used in the platform, high ruggedness is achieved e.g., injection of 100 non-filtrated water samples did not result in a pressure rise/clogging of the SPE/capillary columns (inner diameter 300 μm. In addition, satisfactory retention time stability and chromatographic resolution were also features of the system. The potential of the platform for environmental water samples was demonstrated with various pharmaceutical products, which had detection limits (LOD in the 0.05–12.5 ng/L range. Between-day and within-day repeatability of selected analytes were <20% RSD.

  6. Improved tolerance of abdominal large-volume radiotherapy due to ornithine aspartate

    International Nuclear Information System (INIS)

    Kuttig, H.

    1983-01-01

    The influence of ornithine aspartate on supporting the hepatic function was investigated in a group of 47 patients with tumour dissemination in the pelvic and abdominal region, randomised on the basis of the progress of the serum enzymes GOT, GPT, LAD, LDH, LAP and the alkaline phosphatase during and following completion of a course of large-volume radiotherapy. The adjuvant therapy with ornithine aspartate resulted in reduced enzyme movement with an earlier tendency to normalisation. The results, which are borne out by statistics, clearly show an improvement in the hepatic function on detoxication of toxic degradation products of radiotherapy with reduced impairment of the body's own defence mechanisms. Subjectively too, the course of treatment with ornithine aspartate showed a reduced ratio of side effects as regards lassitude and impairment of the patient's general well-being as compared with the group of patients to whom ornithine aspartate was not simultaneously administered. (orig.) [de

  7. The position response of a large-volume segmented germanium detector

    International Nuclear Information System (INIS)

    Descovich, M.; Nolan, P.J.; Boston, A.J.; Dobson, J.; Gros, S.; Cresswell, J.R.; Simpson, J.; Lazarus, I.; Regan, P.H.; Valiente-Dobon, J.J.; Sellin, P.; Pearson, C.J.

    2005-01-01

    The position response of a large-volume segmented coaxial germanium detector is reported. The detector has 24-fold segmentation on its outer contact. The output from each contact was sampled with fast digital signal processing electronics in order to determine the position of the γ-ray interaction from the signal pulse shape. The interaction position was reconstructed in a polar coordinate system by combining the radial information, contained in the rise-time of the pulse leading edge, with the azimuthal information, obtained from the magnitude of the transient charge signals induced on the neighbouring segments. With this method, a position resolution of 3-7mm is achieved in both the radial and the azimuthal directions

  8. The position response of a large-volume segmented germanium detector

    Energy Technology Data Exchange (ETDEWEB)

    Descovich, M. [Oliver Lodge Laboratory, Physics Department, University of Liverpool, Liverpool L69 7ZE (United Kingdom)]. E-mail: mdescovich@lbl.gov; Nolan, P.J. [Oliver Lodge Laboratory, Physics Department, University of Liverpool, Liverpool L69 7ZE (United Kingdom); Boston, A.J. [Oliver Lodge Laboratory, Physics Department, University of Liverpool, Liverpool L69 7ZE (United Kingdom); Dobson, J. [Oliver Lodge Laboratory, Physics Department, University of Liverpool, Liverpool L69 7ZE (United Kingdom); Gros, S. [Oliver Lodge Laboratory, Physics Department, University of Liverpool, Liverpool L69 7ZE (United Kingdom); Cresswell, J.R. [Oliver Lodge Laboratory, Physics Department, University of Liverpool, Liverpool L69 7ZE (United Kingdom); Simpson, J. [CCLRC Daresbury Laboratory, Daresbury, Warrington, Cheshire WA4 4AD (United Kingdom); Lazarus, I. [CCLRC Daresbury Laboratory, Daresbury, Warrington, Cheshire WA4 4AD (United Kingdom); Regan, P.H. [Department of Physics, University of Surrey, Guildford GU2 7XH (United Kingdom); Valiente-Dobon, J.J. [Department of Physics, University of Surrey, Guildford GU2 7XH (United Kingdom); Sellin, P. [Department of Physics, University of Surrey, Guildford GU2 7XH (United Kingdom); Pearson, C.J. [Department of Physics, University of Surrey, Guildford GU2 7XH (United Kingdom)

    2005-11-21

    The position response of a large-volume segmented coaxial germanium detector is reported. The detector has 24-fold segmentation on its outer contact. The output from each contact was sampled with fast digital signal processing electronics in order to determine the position of the {gamma}-ray interaction from the signal pulse shape. The interaction position was reconstructed in a polar coordinate system by combining the radial information, contained in the rise-time of the pulse leading edge, with the azimuthal information, obtained from the magnitude of the transient charge signals induced on the neighbouring segments. With this method, a position resolution of 3-7mm is achieved in both the radial and the azimuthal directions.

  9. Floating substructure flexibility of large-volume 10MW offshore wind turbine platforms in dynamic calculations

    International Nuclear Information System (INIS)

    Borg, Michael; Hansen, Anders Melchior; Bredmose, Henrik

    2016-01-01

    Designing floating substructures for the next generation of 10MW and larger wind turbines has introduced new challenges in capturing relevant physical effects in dynamic simulation tools. In achieving technically and economically optimal floating substructures, structural flexibility may increase to the extent that it becomes relevant to include in addition to the standard rigid body substructure modes which are typically described through linear radiation-diffraction theory. This paper describes a method for the inclusion of substructural flexibility in aero-hydro-servo-elastic dynamic simulations for large-volume substructures, including wave-structure interactions, to form the basis of deriving sectional loads and stresses within the substructure. The method is applied to a case study to illustrate the implementation and relevance. It is found that the flexible mode is significantly excited in an extreme event, indicating an increase in predicted substructure internal loads. (paper)

  10. Development of metallic molds for the large volume plastic scintillator fabrication

    International Nuclear Information System (INIS)

    Calvo, Wilson A.P.; Vieira, Jose M.; Rela, Paulo R.; Bruzinga, Wilson A.; Araujo, Eduardo P.; Costa Junior, Nelson P.; Hamada, Margarida M.

    1997-01-01

    The plastic scintillators are radiation detectors made of organic fluorescent compounds dissolved in a solidified polymer matrix. The manufacturing process of large volume detectors (55 liters) at low cost, by polymerization of the styrene monomer plus PPO and POPOP scintillators, was studied in this paper. Metallic molds of ASTM 1200 aluminum and AISI 304 stainless steel were produced by TIG welding process since the polymerization reaction is very exothermic. The measurements of transmittance, luminescence, X-ray fluorescence and light output were carried out in the plastic scintillators made using different metallic molds. The characterization results of the detectors produced in an open system using ASTM 1200 aluminum mold show that there is not quality change in the scintillator, even with aluminum being considered as unstable for styrene monomer. Therefore, the ASTM 1200 aluminum was found to be the best alternative to produce the detector by an open system polymerization. (author). 11 refs., 8 figs., 1 tab

  11. The core collapse supernova rate from 24 years of data of the Large Volume Detector

    Science.gov (United States)

    Bruno, G.; Fulgione, W.; Molinario, A.; Vigorito, C.; LVD Collaboration

    2017-09-01

    The Large Volume Detector (LVD) at INFN Laboratori Nazionali del Gran Sasso, Italy is a 1 kt liquid scintillator neutrino observatory mainly designed to study low energy neutrinos from Gravitational Stellar Collapses (GSC) with 100% efficiency over the entire Galaxy. Here we summarize the results of the search for supernova neutrino bursts over the full data set lasting from June 1992 to May 2016 for a total live time of 8211 days. In the lack of a positive observation, either in standalone mode or in coincidence with other experiments, we establish the upper limit to the rate of GSC event in the Milky Way: 0.1 year-1 at 90% c.l..

  12. Dynamic illumination of spatially restricted or large brain volumes via a single tapered optical fiber.

    Science.gov (United States)

    Pisanello, Ferruccio; Mandelbaum, Gil; Pisanello, Marco; Oldenburg, Ian A; Sileo, Leonardo; Markowitz, Jeffrey E; Peterson, Ralph E; Della Patria, Andrea; Haynes, Trevor M; Emara, Mohamed S; Spagnolo, Barbara; Datta, Sandeep Robert; De Vittorio, Massimo; Sabatini, Bernardo L

    2017-08-01

    Optogenetics promises precise spatiotemporal control of neural processes using light. However, the spatial extent of illumination within the brain is difficult to control and cannot be adjusted using standard fiber optics. We demonstrate that optical fibers with tapered tips can be used to illuminate either spatially restricted or large brain volumes. Remotely adjusting the light input angle to the fiber varies the light-emitting portion of the taper over several millimeters without movement of the implant. We use this mode to activate dorsal versus ventral striatum of individual mice and reveal different effects of each manipulation on motor behavior. Conversely, injecting light over the full numerical aperture of the fiber results in light emission from the entire taper surface, achieving broader and more efficient optogenetic activation of neurons, compared to standard flat-faced fiber stimulation. Thus, tapered fibers permit focal or broad illumination that can be precisely and dynamically matched to experimental needs.

  13. Development of a spatially uniform fast ionization wave in a large-volume discharge

    International Nuclear Information System (INIS)

    Zatsepin, D.V.; Starikovskaya, S.M.; Starikovskii, A.Yu.

    1998-01-01

    A study is made of a high-voltage nanosecond breakdown in the form of a fast ionization wave produced in a large-volume (401) discharge chamber. The propagation speed of the wave front and the integral energy deposition in a plasma are measured for various regimes of the air discharge at pressures of 10 -2 -4 Torr. A high degree of both the spatial uniformity of the discharge and the reproducibility of the discharge parameters is obtained. The possibility of the development of a fast ionization wave in an electrodeless system is demonstrated. A transition of the breakdown occurring in the form of a fast ionization wave into the streamer breakdown is observed. It is shown that such discharges are promising for technological applications

  14. Radio-chemical dosage of 90Sr in large volumes of drinking water

    International Nuclear Information System (INIS)

    Jeanmaire, L.; Patti, F.; Bullier, D.

    1965-01-01

    I. Principle of the method: 1. Fixing on a resin of all the cations present in the water. 2. Elution using 5 N nitric acid and precipitation of strontium as the carbonate. 3. Concentration of the strontium using the fuming nitric acid method. 4. Purification of the strontium on a resin by selective elution with ammonium citrate. 5. The strontium-90 is measured by separation at the 90 Y equilibrium in the form of the oxalate which is then counted. II. Advantages of the method The concentration of the radio-activity starting from large volumes (100 l) is generally tedious but this method which makes use of a fixation on a cationic resin makes it very simple. The rest of the method consists of a series of simple chemical operations using ion-exchange on resins and coprecipitation. Finally, it is possible to dose stable strontium. (authors) [fr

  15. Aerodynamics of the Large-Volume, Flow-Through Detector System. Final report

    International Nuclear Information System (INIS)

    Reed, H.; Saric, W.; Laananen, D.; Martinez, C.; Carrillo, R.; Myers, J.; Clevenger, D.

    1996-03-01

    The Large-Volume Flow-Through Detector System (LVFTDS) was designed to monitor alpha radiation from Pu, U, and Am in mixed-waste incinerator offgases; however, it can be adapted to other important monitoring uses that span a number of potential markets, including site remediation, indoor air quality, radon testing, and mine shaft monitoring. Goal of this effort was to provide mechanical design information for installation of LVFTDS in an incinerator, with emphasis on ability to withstand the high temperatures and high flow rates expected. The work was successfully carried out in three stages: calculation of pressure drop through the system, materials testing to determine surrogate materials for wind-tunnel testing, and wind-tunnel testing of an actual configuration

  16. Electrically-cooled HPGe detector for advanced x-ray spectroscopy and imaging

    Energy Technology Data Exchange (ETDEWEB)

    Marian, V.; Clauss, J.; Pirard, B.; Quirin, P.; Flamanc, J.; Lampert, M.O. [CANBERRA France, Parc des Tanneries, 1, chemin de la roseraie, 67380 Lingolsheim (France)

    2015-07-01

    High Purity Germanium (HPGe) detectors are used for high-resolution x- and gamma-ray spectroscopy. For their operation, the necessary cryogenic cooling is performed with liquid nitrogen or with electromechanical coolers. Although mature and industrialized solutions, most of HPGe detectors integrating electrical coolers present a limited spectroscopic performance due to the generated mechanical vibration and electromagnetic interference. This paper describes a novel HPGe detector, specifically designed to address the challenges of ultimate x-ray spectroscopy and imaging applications. Due to the stringent demands associated with nano-scale imaging in synchrotron applications, a custom-designed cryostat was built around a Canberra CP5-Plus electrical cooler featuring extremely low vibration levels and high cooling power. The heat generated by the cryo-cooler itself, as well as the electronics, is evacuated via an original liquid cooling circuit. This architecture can also be used to address high ambient temperature, which does not allow conventional cryo-coolers to work properly. The multichannel detector head can consist of a segmented monolithic HPGe sensor, or several closely packed sensors. Each sensor channel is read out by state-of-the-art pulse-reset preamplifiers in order to achieve excellent energy resolution for count rates in excess of 1 Mcps. The sensitive electronics are located in EMI-proof housings to avoid any interference from other devices on a beam-line. The front-end of the detector is built using selected high-purity materials and alloys to avoid any fluorescence effects. We present a detailed description of the detector design and we report on its performance. A discussion is also given on the use of electrically cooled HPGe detectors for applications requiring ultimate energy resolution, such as synchrotron, medicine or nuclear industry. (authors)

  17. Flow-through electroporation based on constant voltage for large-volume transfection of cells.

    Science.gov (United States)

    Geng, Tao; Zhan, Yihong; Wang, Hsiang-Yu; Witting, Scott R; Cornetta, Kenneth G; Lu, Chang

    2010-05-21

    Genetic modification of cells is a critical step involved in many cell therapy and gene therapy protocols. In these applications, cell samples of large volume (10(8)-10(9)cells) are often processed for transfection. This poses new challenges for current transfection methods and practices. Here we present a novel flow-through electroporation method for delivery of genes into cells at high flow rates (up to approximately 20 mL/min) based on disposable microfluidic chips, a syringe pump, and a low-cost direct current (DC) power supply that provides a constant voltage. By eliminating pulse generators used in conventional electroporation, we dramatically lowered the cost of the apparatus and improved the stability and consistency of the electroporation field for long-time operation. We tested the delivery of pEFGP-C1 plasmids encoding enhanced green fluorescent protein into Chinese hamster ovary (CHO-K1) cells in the devices of various dimensions and geometries. Cells were mixed with plasmids and then flowed through a fluidic channel continuously while a constant voltage was established across the device. Together with the applied voltage, the geometry and dimensions of the fluidic channel determined the electrical parameters of the electroporation. With the optimal design, approximately 75% of the viable CHO cells were transfected after the procedure. We also generalize the guidelines for scaling up these flow-through electroporation devices. We envision that this technique will serve as a generic and low-cost tool for a variety of clinical applications requiring large volume of transfected cells. Copyright 2010 Elsevier B.V. All rights reserved.

  18. Determination of the dead layer and full-energy peak efficiency of an HPGe detector using the MCNP code and experimental results

    Directory of Open Access Journals (Sweden)

    M Moeinifar

    2017-02-01

    Full Text Available One important factor in using an High Purity Germanium (HPGe detector is its efficiency that highly depends on the geometry and absorption factors, so that when the configuration of source-detector geometry is changed, the detector efficiency must be re-measured. The best way of determining the efficiency of a detector is measuring the efficiency of standard sources. But considering the fact that standard sources are hardly available and it is time consuming to find them, determinig the efficiency by simulation which gives enough efficiency in less time, is important. In this study, the dead layer thickness and the full-energy peak efficiency of an HPGe detector was obtained by Monte Carlo simulation, using MCNPX code. For this, we first measured gamma–ray spectra for different sources placed at various distances from the detector and stored the measured spectra obtained. Then the obtained spectra were simulated under similar conditions in vitro.At first, the whole volume of germanium was regarded as active, and the obtaind spectra from calculation were compared with the corresponding experimental spectra. Comparison of the calculated spectra with the measured spectra showed considerable differences. By making small variations in the dead layer thickness of the detector (about a few hundredths of a millimeter in the simulation program, we tried to remove these differences and in this way a dead layer of 0.57 mm was obtained for the detector. By incorporating this value for the dead layer in the simulating program, the full-energy peak efficiency of the detector was then obtained both by experiment and by simulation, for various sources at various distances from the detector, and both methods showed good agreements. Then, using MCNP code and considering the exact measurement system, one can conclude that the efficiency of an HPGe detector for various source-detector geometries can be calculated with rather good accuracy by simulation method

  19. Large volume serial section tomography by Xe Plasma FIB dual beam microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Burnett, T.L. [School of Materials, University of Manchester, Manchester M13 9PL (United Kingdom); FEI Company, Achtseweg Noord 5, Bldg, 5651 GG, Eindhoven (Netherlands); Kelley, R. [FEI Company, 5350 NE Dawson Creek Drive, Hillsboro, OR 97124 (United States); Winiarski, B. [School of Materials, University of Manchester, Manchester M13 9PL (United Kingdom); FEI Company, Achtseweg Noord 5, Bldg, 5651 GG, Eindhoven (Netherlands); Contreras, L. [FEI Company, 5350 NE Dawson Creek Drive, Hillsboro, OR 97124 (United States); Daly, M.; Gholinia, A.; Burke, M.G. [School of Materials, University of Manchester, Manchester M13 9PL (United Kingdom); Withers, P.J., E-mail: P.J.Withers@manchester.ac.uk [School of Materials, University of Manchester, Manchester M13 9PL (United Kingdom); BP International Centre for Advanced Materials, University of Manchester, Manchester M13 9PL (United Kingdom)

    2016-02-15

    Ga{sup +} Focused Ion Beam-Scanning Electron Microscopes (FIB-SEM) have revolutionised the level of microstructural information that can be recovered in 3D by block face serial section tomography (SST), as well as enabling the site-specific removal of smaller regions for subsequent transmission electron microscope (TEM) examination. However, Ga{sup +} FIB material removal rates limit the volumes and depths that can be probed to dimensions in the tens of microns range. Emerging Xe{sup +} Plasma Focused Ion Beam-Scanning Electron Microscope (PFIB-SEM) systems promise faster removal rates. Here we examine the potential of the method for large volume serial section tomography as applied to bainitic steel and WC–Co hard metals. Our studies demonstrate that with careful control of milling parameters precise automated serial sectioning can be achieved with low levels of milling artefacts at removal rates some 60× faster. Volumes that are hundreds of microns in dimension have been collected using fully automated SST routines in feasible timescales (<24 h) showing good grain orientation contrast and capturing microstructural features at the tens of nanometres to the tens of microns scale. Accompanying electron back scattered diffraction (EBSD) maps show high indexing rates suggesting low levels of surface damage. Further, under high current Ga{sup +} FIB milling WC–Co is prone to amorphisation of WC surface layers and phase transformation of the Co phase, neither of which have been observed at PFIB currents as high as 60 nA at 30 kV. Xe{sup +} PFIB dual beam microscopes promise to radically extend our capability for 3D tomography, 3D EDX, 3D EBSD as well as correlative tomography. - Highlights: • The uptake of dual beam FIBs has been rapid but long milling times have limited imaged volumes to tens of micron dimensions. • Emerging plasma Xe{sup +} PFIB-SEM technology offers materials removal rates at least 60× greater than conventional Ga{sup +} FIB systems with

  20. Volume Visualization and Compositing on Large-Scale Displays Using Handheld Touchscreen Interaction

    KAUST Repository

    Gastelum, Cristhopper Jacobo Armenta

    2011-07-27

    Advances in the physical sciences have progressively delivered ever increasing, already extremely large data sets to be analyzed. High performance volume rendering has become critical to the scientists for a better understanding of the massive amounts of data to be visualized. Cluster based rendering systems have become the base line to achieve the power and flexibility required to perform such task. Furthermore, display arrays have become the most suitable solution to display these data sets at their natural size and resolution which can be critical for human perception and evaluation. The work in this thesis aims at improving the scalability and usability of volume rendering systems that target visualization on display arrays. The first part deals with improving the performance by introducing the implementations of two parallel compositing algorithms for volume rendering: direct send and binary swap. The High quality Volume Rendering (HVR) framework has been extended to accommodate parallel compositing where previously only serial compositing was possible. The preliminary results show improvements in the compositing times for direct send even for a small number of processors. Unfortunately, the results of binary swap exhibit a negative behavior. This is due to the naive use of the graphics hardware blending mechanism. The expensive transfers account for the lengthy compositing times. The second part targets the development of scalable and intuitive interaction mechanisms. It introduces the development of a new client application for multitouch tablet devices, like the Apple iPad. The main goal is to provide the HVR framework, that has been extended to use tiled displays, a more intuitive and portable interaction mechanism that can get advantage of the new environment. The previous client is a PC application for the typical desktop settings that use a mouse and keyboard as sources of interaction. The current implementation of the client lets the user steer and

  1. Large volume serial section tomography by Xe Plasma FIB dual beam microscopy

    International Nuclear Information System (INIS)

    Burnett, T.L.; Kelley, R.; Winiarski, B.; Contreras, L.; Daly, M.; Gholinia, A.; Burke, M.G.; Withers, P.J.

    2016-01-01

    Ga + Focused Ion Beam-Scanning Electron Microscopes (FIB-SEM) have revolutionised the level of microstructural information that can be recovered in 3D by block face serial section tomography (SST), as well as enabling the site-specific removal of smaller regions for subsequent transmission electron microscope (TEM) examination. However, Ga + FIB material removal rates limit the volumes and depths that can be probed to dimensions in the tens of microns range. Emerging Xe + Plasma Focused Ion Beam-Scanning Electron Microscope (PFIB-SEM) systems promise faster removal rates. Here we examine the potential of the method for large volume serial section tomography as applied to bainitic steel and WC–Co hard metals. Our studies demonstrate that with careful control of milling parameters precise automated serial sectioning can be achieved with low levels of milling artefacts at removal rates some 60× faster. Volumes that are hundreds of microns in dimension have been collected using fully automated SST routines in feasible timescales (<24 h) showing good grain orientation contrast and capturing microstructural features at the tens of nanometres to the tens of microns scale. Accompanying electron back scattered diffraction (EBSD) maps show high indexing rates suggesting low levels of surface damage. Further, under high current Ga + FIB milling WC–Co is prone to amorphisation of WC surface layers and phase transformation of the Co phase, neither of which have been observed at PFIB currents as high as 60 nA at 30 kV. Xe + PFIB dual beam microscopes promise to radically extend our capability for 3D tomography, 3D EDX, 3D EBSD as well as correlative tomography. - Highlights: • The uptake of dual beam FIBs has been rapid but long milling times have limited imaged volumes to tens of micron dimensions. • Emerging plasma Xe + PFIB-SEM technology offers materials removal rates at least 60× greater than conventional Ga + FIB systems with comparable or less damage. • The

  2. Process automation system for integration and operation of Large Volume Plasma Device

    International Nuclear Information System (INIS)

    Sugandhi, R.; Srivastava, P.K.; Sanyasi, A.K.; Srivastav, Prabhakar; Awasthi, L.M.; Mattoo, S.K.

    2016-01-01

    Highlights: • Analysis and design of process automation system for Large Volume Plasma Device (LVPD). • Data flow modeling for process model development. • Modbus based data communication and interfacing. • Interface software development for subsystem control in LabVIEW. - Abstract: Large Volume Plasma Device (LVPD) has been successfully contributing towards understanding of the plasma turbulence driven by Electron Temperature Gradient (ETG), considered as a major contributor for the plasma loss in the fusion devices. Large size of the device imposes certain difficulties in the operation, such as access of the diagnostics, manual control of subsystems and large number of signals monitoring etc. To achieve integrated operation of the machine, automation is essential for the enhanced performance and operational efficiency. Recently, the machine is undergoing major upgradation for the new physics experiments. The new operation and control system consists of following: (1) PXIe based fast data acquisition system for the equipped diagnostics; (2) Modbus based Process Automation System (PAS) for the subsystem controls and (3) Data Utilization System (DUS) for efficient storage, processing and retrieval of the acquired data. In the ongoing development, data flow model of the machine’s operation has been developed. As a proof of concept, following two subsystems have been successfully integrated: (1) Filament Power Supply (FPS) for the heating of W- filaments based plasma source and (2) Probe Positioning System (PPS) for control of 12 number of linear probe drives for a travel length of 100 cm. The process model of the vacuum production system has been prepared and validated against acquired pressure data. In the next upgrade, all the subsystems of the machine will be integrated in a systematic manner. The automation backbone is based on 4-wire multi-drop serial interface (RS485) using Modbus communication protocol. Software is developed on LabVIEW platform using

  3. Process automation system for integration and operation of Large Volume Plasma Device

    Energy Technology Data Exchange (ETDEWEB)

    Sugandhi, R., E-mail: ritesh@ipr.res.in; Srivastava, P.K.; Sanyasi, A.K.; Srivastav, Prabhakar; Awasthi, L.M.; Mattoo, S.K.

    2016-11-15

    Highlights: • Analysis and design of process automation system for Large Volume Plasma Device (LVPD). • Data flow modeling for process model development. • Modbus based data communication and interfacing. • Interface software development for subsystem control in LabVIEW. - Abstract: Large Volume Plasma Device (LVPD) has been successfully contributing towards understanding of the plasma turbulence driven by Electron Temperature Gradient (ETG), considered as a major contributor for the plasma loss in the fusion devices. Large size of the device imposes certain difficulties in the operation, such as access of the diagnostics, manual control of subsystems and large number of signals monitoring etc. To achieve integrated operation of the machine, automation is essential for the enhanced performance and operational efficiency. Recently, the machine is undergoing major upgradation for the new physics experiments. The new operation and control system consists of following: (1) PXIe based fast data acquisition system for the equipped diagnostics; (2) Modbus based Process Automation System (PAS) for the subsystem controls and (3) Data Utilization System (DUS) for efficient storage, processing and retrieval of the acquired data. In the ongoing development, data flow model of the machine’s operation has been developed. As a proof of concept, following two subsystems have been successfully integrated: (1) Filament Power Supply (FPS) for the heating of W- filaments based plasma source and (2) Probe Positioning System (PPS) for control of 12 number of linear probe drives for a travel length of 100 cm. The process model of the vacuum production system has been prepared and validated against acquired pressure data. In the next upgrade, all the subsystems of the machine will be integrated in a systematic manner. The automation backbone is based on 4-wire multi-drop serial interface (RS485) using Modbus communication protocol. Software is developed on LabVIEW platform using

  4. 'Finite' non-Gaussianities and tensor-scalar ratio in large volume Swiss-cheese compactifications

    International Nuclear Information System (INIS)

    Misra, Aalok; Shukla, Pramod

    2009-01-01

    Developing on the ideas of (Section 4 of) [A. Misra, P. Shukla, Moduli stabilization, large-volume dS minimum without anti-D3-branes, (non-)supersymmetric black hole attractors and two-parameter Swiss cheese Calabi-Yau's, Nucl. Phys. B 799 (2008) 165-198, (arXiv: 0707.0105)] and [A. Misra, P. Shukla, Large volume axionic Swiss-cheese inflation, Nucl. Phys. B 800 (2008) 384-400, (arXiv: 0712.1260 [hep-th])] and using the formalisms of [S. Yokoyama, T. Suyama, T. Tanaka, Primordial non-Gaussianity in multi-scalar slow-roll inflation, (arXiv: 0705.3178 [astro-ph]); S. Yokoyama, T. Suyama, T. Tanaka, Primordial non-Gaussianity in multi-scalar inflation, Phys. Rev. D 77 (2008) 083511, (arXiv: 0711.2920 [astro-ph])], after inclusion of perturbative and non-perturbative α' corrections to the Kaehler potential and (D1- and D3-)instanton generated superpotential, we show the possibility of getting finite values for the non-linear parameter f NL while looking for non-Gaussianities in type IIB compactifications on orientifolds of the Swiss cheese Calabi-Yau WCP 4 [1,1,1,6,9] in the L(arge) V(olume) S(cenarios) limit. We show the same in two contexts. First is multi-field slow-roll inflation with D3-instanton contribution coming from a large number of multiple wrappings of a single (Euclidean) D3-brane around the 'small' divisor yielding f NL ∼O(1). The second is when the slow-roll conditions are violated and for the number of the aforementioned D3-instanton wrappings being of O(1) but more than one, yielding f NL ∼O(1). Based on general arguments not specific to our (string-theory) set-up, we argue that requiring curvature perturbations not to grow at horizon crossing and at super-horizon scales, automatically picks out hybrid inflationary scenarios which in our set up can yield f NL ∼O(1) and tensor-scalar ratio of O(10 -2 ). For all our calculations, the world-sheet instanton contributions to the Kaehler potential coming from the non-perturbative α ' corrections

  5. Major risk from rapid, large-volume landslides in Europe (EU Project RUNOUT)

    Science.gov (United States)

    Kilburn, Christopher R. J.; Pasuto, Alessandro

    2003-08-01

    Project RUNOUT has investigated methods for reducing the risk from large-volume landslides in Europe, especially those involving rapid rates of emplacement. Using field data from five test sites (Bad Goisern and Köfels in Austria, Tessina and Vajont in Italy, and the Barranco de Tirajana in Gran Canaria, Spain), the studies have developed (1) techniques for applying geomorphological investigations and optical remote sensing to map landslides and their evolution; (2) analytical, numerical, and cellular automata models for the emplacement of sturzstroms and debris flows; (3) a brittle-failure model for forecasting catastrophic slope failure; (4) new strategies for integrating large-area Global Positioning System (GPS) arrays with local geodetic monitoring networks; (5) methods for raising public awareness of landslide hazards; and (6) Geographic Information System (GIS)-based databases for the test areas. The results highlight the importance of multidisciplinary studies of landslide hazards, combining subjects as diverse as geology and geomorphology, remote sensing, geodesy, fluid dynamics, and social profiling. They have also identified key goals for an improved understanding of the physical processes that govern landslide collapse and runout, as well as for designing strategies for raising public awareness of landslide hazards and for implementing appropriate land management policies for reducing landslide risk.

  6. Active species in a large volume N2-O2 post-discharge reactor

    International Nuclear Information System (INIS)

    Kutasi, K; Pintassilgo, C D; Loureiro, J; Coelho, P J

    2007-01-01

    A large volume post-discharge reactor placed downstream from a flowing N 2 -O 2 microwave discharge is modelled using a three-dimensional hydrodynamic model. The density distributions of the most populated active species present in the reactor-O( 3 P), O 2 (a 1 Δ g ), O 2 (b 1 Σ g + ), NO(X 2 Π), NO(A 2 Σ + ), NO(B 2 Π), NO 2 (X), O 3 , O 2 (X 3 Σ g - ) and N( 4 S)-are calculated and the main source and loss processes for each species are identified for two discharge conditions: (i) p = 2 Torr, f = 2450 MHz, and (ii) p = 8 Torr, f = 915 MHz; in the case of a N 2 -2%O 2 mixture composition and gas flow rate of 2 x 10 3 sccm. The modification of the species relative densities by changing the oxygen percentage in the initial gas mixture composition, in the 0.2%-5% range, are presented. The possible tuning of the species concentrations in the reactor by changing the size of the connecting afterglow tube between the active discharge and the large post-discharge reactor is investigated as well

  7. Numerical expressions for the computation of coincidence-summing correction factors in gamma-ray spectrometry with HPGe detectors

    International Nuclear Information System (INIS)

    Rizzo, S.; Tomarchio, E.

    2008-01-01

    Full text: The analytical relations used to compute the coincidence-summing effects on spectral response of Ge semiconductor detectors are quite complex and involve full-energy peak and total efficiencies. For point-sources, a general method for calculating the correction factors for gamma ray coincidences has been formulated by Andreev et al. and used by Schima and Hoppes to obtain γ-X K coincidence correction expressions for 17 nuclides. However, because the higher-order terms are neglected, the expressions supplied do not give reliable results in the case of short sample-detector distances. Using the formulae given by Morel et al.[3] and Lepy et al.[4], we have developed a computer program able to get numerical expressions to compute γ-γ e γ-X K coincidence summing corrections for point sources. Only full-energy peak and total efficiencies are needed. Alternatively, values of peak-to-total ratio can be introduced. For extended sources, the same expressions can be always considered with the introduction of 'effective efficiencies' as defined by Arnold and Sima, i.e. an average over the source volume of the spatial distribution of the elementary photon source total efficiency, weighted by the corresponding peak efficiency. We have considered the most used calibration radioisotopes as well as fission products, activation products and environmental isotopes. All decay data were taken from the most recent volumes of 'Table of Radionuclides', CEA Monographie BIPM-5 and a suitable matrix representation of a decay scheme was adopted. For the sake of brevity, we provide for each nuclide a set of expressions for the more intense gamma emissions, considered sufficient for most applications. However, numerical expressions are available for all the stored gamma transitions and can be obtained on request. As examples of the use of the expressions, the evaluation of correction values for point sources and a particulate sample reduced to a 6x6x0.7 cm packet - with reference

  8. Analytical and Experimental Investigation of Mixing in Large Passive Containment Volumes

    International Nuclear Information System (INIS)

    Peterson, Per F.

    2002-01-01

    This final report details results from the past three years of the three-year UC Berkeley NEER investigation of mixing phenomena in large-scale passive reactor containments. We have completed all of our three-year deliverables specified in our proposal, as summarized for each deliverable in the body of this report, except for the experiments of steam condensation in the presence of noncondensable gas. We have particularly exiting results from the experiments studying the mixing in large insulated containment with a vertical cooling plate. These experiments now have shown why augmentation has been observed in wall-condensation experiments due to the momentum of the steam break-flow entering large volumes. More importantly, we also have shown that the forced-jet augmentation can be predicted using relatively simple correlations, and that it is independent of the break diameter and depends only on the break flow orientation, location, and momentum. This suggests that we will now be able to take credit for this augmentation in reactor safety analysis, improving safety margins for containment structures. We have finished the version 1 of 1-D Lagrangian flow and heat transfer code BMIX++. This version has ability to solve many complex stratified problems, such as multi-components problems, multi-enclosures problems (two enclosures connected by one connection for the current version), incompressible and compressible problems, multi jets, plumes, sinks in one enclosure problems, problems with wall conduction, and the combinations of the above problems. We believe the BMIX++ code is a very powerful computation tool to study stratified enclosures mixing problems

  9. Albumin infusion in patients undergoing large-volume paracentesis: a meta-analysis of randomized trials.

    Science.gov (United States)

    Bernardi, Mauro; Caraceni, Paolo; Navickis, Roberta J; Wilkes, Mahlon M

    2012-04-01

    Albumin infusion reduces the incidence of postparacentesis circulatory dysfunction among patients with cirrhosis and tense ascites, as compared with no treatment. Treatment alternatives to albumin, such as artificial colloids and vasoconstrictors, have been widely investigated. The aim of this meta-analysis was to determine whether morbidity and mortality differ between patients receiving albumin versus alternative treatments. The meta-analysis included randomized trials evaluating albumin infusion in patients with tense ascites. Primary endpoints were postparacentesis circulatory dysfunction, hyponatremia, and mortality. Eligible trials were sought by multiple methods, including computer searches of bibliographic and abstract databases and the Cochrane Library. Results were quantitatively combined under a fixed-effects model. Seventeen trials with 1,225 total patients were included. There was no evidence of heterogeneity or publication bias. Compared with alternative treatments, albumin reduced the incidence of postparacentesis circulatory dysfunction (odds ratio [OR], 0.39; 95% confidence interval [CI], 0.27-0.55). Significant reductions in that complication by albumin were also shown in subgroup analyses versus each of the other volume expanders tested (e.g., dextran, gelatin, hydroxyethyl starch, and hypertonic saline). The occurrence of hyponatremia was also decreased by albumin, compared with alternative treatments (OR, 0.58; 95% CI, 0.39-0.87). In addition, mortality was lower in patients receiving albumin than alternative treatments (OR, 0.64; 95% CI, 0.41-0.98). This meta-analysis provides evidence that albumin reduces morbidity and mortality among patients with tense ascites undergoing large-volume paracentesis, as compared with alternative treatments investigated thus far. Copyright © 2011 American Association for the Study of Liver Diseases.

  10. PVR: Patch-to-Volume Reconstruction for Large Area Motion Correction of Fetal MRI.

    Science.gov (United States)

    Alansary, Amir; Rajchl, Martin; McDonagh, Steven G; Murgasova, Maria; Damodaram, Mellisa; Lloyd, David F A; Davidson, Alice; Rutherford, Mary; Hajnal, Joseph V; Rueckert, Daniel; Kainz, Bernhard

    2017-10-01

    In this paper, we present a novel method for the correction of motion artifacts that are present in fetal magnetic resonance imaging (MRI) scans of the whole uterus. Contrary to current slice-to-volume registration (SVR) methods, requiring an inflexible anatomical enclosure of a single investigated organ, the proposed patch-to-volume reconstruction (PVR) approach is able to reconstruct a large field of view of non-rigidly deforming structures. It relaxes rigid motion assumptions by introducing a specific amount of redundant information that is exploited with parallelized patchwise optimization, super-resolution, and automatic outlier rejection. We further describe and provide an efficient parallel implementation of PVR allowing its execution within reasonable time on commercially available graphics processing units, enabling its use in the clinical practice. We evaluate PVR's computational overhead compared with standard methods and observe improved reconstruction accuracy in the presence of affine motion artifacts compared with conventional SVR in synthetic experiments. Furthermore, we have evaluated our method qualitatively and quantitatively on real fetal MRI data subject to maternal breathing and sudden fetal movements. We evaluate peak-signal-to-noise ratio, structural similarity index, and cross correlation with respect to the originally acquired data and provide a method for visual inspection of reconstruction uncertainty. We further evaluate the distance error for selected anatomical landmarks in the fetal head, as well as calculating the mean and maximum displacements resulting from automatic non-rigid registration to a motion-free ground truth image. These experiments demonstrate a successful application of PVR motion compensation to the whole fetal body, uterus, and placenta.

  11. Annealing as grown large volume CZT single crystals for increased spectral resolution

    International Nuclear Information System (INIS)

    Li, Longxia

    2008-01-01

    The spectroscopic performance of current large-volume Cadmium 10% Zinc Telluride, Cd 0.9 Zn 0.1 Te, (CZT) detectors is impaired by cumulative effect of tellurium precipitates (secondary phases) presented in CZT single-crystal grown by low-pressure Bridgman techniques(1). This statistical effect may limit the energy resolution of large-volume CZT detectors (typically 2-5% at 662 keV for 12-mm thick devices). The stochastic nature of the interaction prevents the use of any electronic or digital charge correction techniques without a significant reduction in the detector efficiency. This volume constraint hampers the utility of CZT since the detectors are inefficient at detecting photons >1MeV and/or in low fluency situations. During the project, seven runs CZT ingots have been grown, in these ingots the indium dopant concentrations have been changed in the range between 0.5ppm to 6ppm. The I-R mapping imaging method has been employed to study the Te-precipitates. The Teprecipitates in as-grown CZT wafers, and after annealing wafers have been systematically studied by using I-R mapping system (home installed, resolution of 1.5 (micro)m). We employed our I-R standard annealing CZT (Zn=4%) procedure or two-steps annealing into radiation CZT (Zn=10%), we achieved the 'non'-Te precipitates (size 10 9-10 (Omega)-cm. We believe that the Te-precipitates are the p-type defects, its reducing number causes the CZT became n+-type, therefore we varied or reduced the indium dapant concentration during the growth and changed the Te-precipitates size and density by using different Cd-temperature and different annealing procedures. We have made the comparisons among Te-precipitates size, density and Indium dopant concentrations, and we found that the CZT with smaller size of Te-precipitates is suitable for radiation uses but non-Te precipitates is impossible to be used in the radiation detectors, because the CZT would became un-dopant or 'intrinsic' with non radiation affection (we

  12. A new large-volume metal reference standard for radioactive waste management.

    Science.gov (United States)

    Tzika, F; Hult, M; Stroh, H; Marissens, G; Arnold, D; Burda, O; Kovář, P; Suran, J; Listkowska, A; Tyminski, Z

    2016-03-01

    A new large-volume metal reference standard has been developed. The intended use is for calibration of free-release radioactivity measurement systems and is made up of cast iron tubes placed inside a box of the size of a Euro-pallet (80 × 120 cm). The tubes contain certified activity concentrations of (60)Co (0.290 ± 0.006 Bq g(-1)) and (110m)Ag (3.05 ± 0.09 Bq g(-1)) (reference date: 30 September 2013). They were produced using centrifugal casting from a smelt into which (60)Co was first added and then one piece of neutron irradiated silver wire was progressively diluted. The iron castings were machined to the desirable dimensions. The final material consists of 12 iron tubes of 20 cm outer diameter, 17.6 cm inner diameter, 40 cm length/height and 245.9 kg total mass. This paper describes the reference standard and the process of determining the reference activity values. © The Author 2015. Published by Oxford University Press.

  13. Low Energy Neutrino Astronomy in the future large-volume liquid-scintillator detector LENA

    International Nuclear Information System (INIS)

    Wurm, Michael; Feilitzsch, F V; Goeger-Neff, M; Lewke, T; Undagoitia, T Marrodan; Oberauer, L; Potzel, W; Todor, S; Winter, J

    2008-01-01

    The recent successes in neutrino physics prove that liquid-scintillator detectors allow to combine high energy resolution, efficient means of background reduction, and a large detection volume. In the planned LENA (Low Energy Neutrino Astronomy) experiment, a target mass of 50 kt will enable the investigation of a variety of terrestrial and astrophysical neutrino sources. The high-statistics spectroscopy of geoneutrinos, solar neutrinos and supernova neutrinos will provide new insights in the heat production processes of Earth and Sun, and the workings of a gravitational collapse. The same measurements will as well investigate neutrino properties as oscillation parameters and mass hierarchy. A first spectroscopic measurement of the low flux of diffuse supernova neutrino background is within the sensitivity of the LENA detector. Finally, a life-time limit of several 1034 years can be set to the proton decay into proton and anti-neutrino, testing the predictions of SUSY theory. The present contribution includes a review of the scientific studies that were performed in the last years as well as a report on currently on-going R and D activities.

  14. Plasma response to electron energy filter in large volume plasma device

    International Nuclear Information System (INIS)

    Sanyasi, A. K.; Awasthi, L. M.; Mattoo, S. K.; Srivastava, P. K.; Singh, S. K.; Singh, R.; Kaw, P. K.

    2013-01-01

    An electron energy filter (EEF) is embedded in the Large Volume Plasma Device plasma for carrying out studies on excitation of plasma turbulence by a gradient in electron temperature (ETG) described in the paper of Mattoo et al. [S. K. Mattoo et al., Phys. Rev. Lett. 108, 255007 (2012)]. In this paper, we report results on the response of the plasma to the EEF. It is shown that inhomogeneity in the magnetic field of the EEF switches on several physical phenomena resulting in plasma regions with different characteristics, including a plasma region free from energetic electrons, suitable for the study of ETG turbulence. Specifically, we report that localized structures of plasma density, potential, electron temperature, and plasma turbulence are excited in the EEF plasma. It is shown that structures of electron temperature and potential are created due to energy dependence of the electron transport in the filter region. On the other hand, although structure of plasma density has origin in the particle transport but two distinct steps of the density structure emerge from dominance of collisionality in the source-EEF region and of the Bohm diffusion in the EEF-target region. It is argued and experimental evidence is provided for existence of drift like flute Rayleigh-Taylor in the EEF plasma

  15. On 'light' fermions and proton stability in 'big divisor' D3/D7 large volume compactifications

    International Nuclear Information System (INIS)

    Misra, Aalok; Shukla, Pramod

    2011-01-01

    Building on our earlier work (Misra and Shukla, Nucl. Phys. B 827:112, 2010; Phys. Lett. B 685:347-352, 2010), we show the possibility of generating ''light'' fermion mass scales of MeV-GeV range (possibly related to the first two generations of quarks/leptons) as well as eV (possibly related to first two generations of neutrinos) in type IIB string theory compactified on Swiss-Cheese orientifolds in the presence of a mobile space-time filling D3-brane restricted to (in principle) stacks of fluxed D7-branes wrapping the ''big'' divisor Σ B . This part of the paper is an expanded version of the latter half of Sect. 3 of a published short invited review (Misra, Mod. Phys. Lett. A 26:1, 2011) written by one of the authors [AM ]. Further, we also show that there are no SUSY GUT-type dimension-five operators corresponding to proton decay, and we estimate the proton lifetime from a SUSY GUT-type four-fermion dimension-six operator to be 10 61 years. Based on GLSM calculations in (Misra and Shukla, Nucl. Phys. B 827:112, 2010) for obtaining the geometric Kaehler potential for the ''big divisor,'' using further the Donaldson's algorithm, we also briefly discuss in the first of the two appendices the metric for the Swiss-Cheese Calabi-Yau used, which we obtain and which becomes Ricci flat in the large-volume limit. (orig.)

  16. Detecting Boosted Dark Matter from the Sun with Large Volume Neutrino Detectors

    Energy Technology Data Exchange (ETDEWEB)

    Berger, Joshua; /SLAC; Cui, Yanou; /Perimeter Inst. Theor. Phys.; Zhao, Yue; /Stanford U., ITP /Stanford U., Phys. Dept.

    2015-04-02

    We study novel scenarios where thermal dark matter (DM) can be efficiently captured in the Sun and annihilate into boosted dark matter. In models with semi-annihilating DM, where DM has a non-minimal stabilization symmetry, or in models with a multi-component DM sector, annihilations of DM can give rise to stable dark sector particles with moderate Lorentz boosts. We investigate both of these possibilities, presenting concrete models as proofs of concept. Both scenarios can yield viable thermal relic DM with masses O(1)-O(100) GeV. Taking advantage of the energetic proton recoils that arise when the boosted DM scatters off matter, we propose a detection strategy which uses large volume terrestrial detectors, such as those designed to detect neutrinos or proton decays. In particular, we propose a search for proton tracks pointing towards the Sun. We focus on signals at Cherenkov-radiation-based detectors such as Super-Kamiokande (SK) and its upgrade Hyper-Kamiokande (HK). We find that with spin-dependent scattering as the dominant DM-nucleus interaction at low energies, boosted DM can leave detectable signals at SK or HK, with sensitivity comparable to DM direct detection experiments while being consistent with current constraints. Our study provides a new search path for DM sectors with non-minimal structure.

  17. On `light' fermions and proton stability in `big divisor' D3/ D7 large volume compactifications

    Science.gov (United States)

    Misra, Aalok; Shukla, Pramod

    2011-06-01

    Building on our earlier work (Misra and Shukla, Nucl. Phys. B 827:112, 2010; Phys. Lett. B 685:347-352, 2010), we show the possibility of generating "light" fermion mass scales of MeV-GeV range (possibly related to the first two generations of quarks/leptons) as well as eV (possibly related to first two generations of neutrinos) in type IIB string theory compactified on Swiss-Cheese orientifolds in the presence of a mobile space-time filling D3-brane restricted to (in principle) stacks of fluxed D7-branes wrapping the "big" divisor Σ B . This part of the paper is an expanded version of the latter half of Sect. 3 of a published short invited review (Misra, Mod. Phys. Lett. A 26:1, 2011) written by one of the authors [AM]. Further, we also show that there are no SUSY GUT-type dimension-five operators corresponding to proton decay, and we estimate the proton lifetime from a SUSY GUT-type four-fermion dimension-six operator to be 1061 years. Based on GLSM calculations in (Misra and Shukla, Nucl. Phys. B 827:112, 2010) for obtaining the geometric Kähler potential for the "big divisor," using further the Donaldson's algorithm, we also briefly discuss in the first of the two appendices the metric for the Swiss-Cheese Calabi-Yau used, which we obtain and which becomes Ricci flat in the large-volume limit.

  18. Translational and Brownian motion in laser-Doppler flowmetry of large tissue volumes

    International Nuclear Information System (INIS)

    Binzoni, T; Leung, T S; Seghier, M L; Delpy, D T

    2004-01-01

    This study reports the derivation of a precise mathematical relationship existing between the different p-moments of the power spectrum of the photoelectric current, obtained from a laser-Doppler flowmeter (LDF), and the red blood cell speed. The main purpose is that both the Brownian (defining the 'biological zero') and the translational movements are taken into account, clarifying in this way what the exact contribution of each parameter is to the LDF derived signals. The derivation of the equations is based on the quasi-elastic scattering theory and holds for multiple scattering (i.e. measurements in large tissue volumes and/or very high red blood cell concentration). The paper also discusses why experimentally there exists a range in which the relationship between the first moment of the power spectrum and the average red blood cells speed may be considered as 'linear' and what are the physiological determinants that can result in nonlinearity. A correct way to subtract the biological zero from the LDF data is also proposed. The findings should help in the design of improved LDF instruments and in the interpretation of experimental data

  19. Coupled Finite Volume and Finite Element Method Analysis of a Complex Large-Span Roof Structure

    Science.gov (United States)

    Szafran, J.; Juszczyk, K.; Kamiński, M.

    2017-12-01

    The main goal of this paper is to present coupled Computational Fluid Dynamics and structural analysis for the precise determination of wind impact on internal forces and deformations of structural elements of a longspan roof structure. The Finite Volume Method (FVM) serves for a solution of the fluid flow problem to model the air flow around the structure, whose results are applied in turn as the boundary tractions in the Finite Element Method problem structural solution for the linear elastostatics with small deformations. The first part is carried out with the use of ANSYS 15.0 computer system, whereas the FEM system Robot supports stress analysis in particular roof members. A comparison of the wind pressure distribution throughout the roof surface shows some differences with respect to that available in the engineering designing codes like Eurocode, which deserves separate further numerical studies. Coupling of these two separate numerical techniques appears to be promising in view of future computational models of stochastic nature in large scale structural systems due to the stochastic perturbation method.

  20. Low Energy Neutrino Astronomy in the future large-volume liquid-scintillator detector LENA

    Energy Technology Data Exchange (ETDEWEB)

    Wurm, Michael; Feilitzsch, F V; Goeger-Neff, M; Lewke, T; Undagoitia, T Marrodan; Oberauer, L; Potzel, W; Todor, S; Winter, J [E15 Chair for Astroparticle Physics, Technische Universitat Miinchen, Physik Department, James-Franck-Str., D-85748 Garching (Germany)

    2008-11-01

    The recent successes in neutrino physics prove that liquid-scintillator detectors allow to combine high energy resolution, efficient means of background reduction, and a large detection volume. In the planned LENA (Low Energy Neutrino Astronomy) experiment, a target mass of 50 kt will enable the investigation of a variety of terrestrial and astrophysical neutrino sources. The high-statistics spectroscopy of geoneutrinos, solar neutrinos and supernova neutrinos will provide new insights in the heat production processes of Earth and Sun, and the workings of a gravitational collapse. The same measurements will as well investigate neutrino properties as oscillation parameters and mass hierarchy. A first spectroscopic measurement of the low flux of diffuse supernova neutrino background is within the sensitivity of the LENA detector. Finally, a life-time limit of several 1034 years can be set to the proton decay into proton and anti-neutrino, testing the predictions of SUSY theory. The present contribution includes a review of the scientific studies that were performed in the last years as well as a report on currently on-going R and D activities.

  1. High-Dimensional Function Approximation With Neural Networks for Large Volumes of Data.

    Science.gov (United States)

    Andras, Peter

    2018-02-01

    Approximation of high-dimensional functions is a challenge for neural networks due to the curse of dimensionality. Often the data for which the approximated function is defined resides on a low-dimensional manifold and in principle the approximation of the function over this manifold should improve the approximation performance. It has been show that projecting the data manifold into a lower dimensional space, followed by the neural network approximation of the function over this space, provides a more precise approximation of the function than the approximation of the function with neural networks in the original data space. However, if the data volume is very large, the projection into the low-dimensional space has to be based on a limited sample of the data. Here, we investigate the nature of the approximation error of neural networks trained over the projection space. We show that such neural networks should have better approximation performance than neural networks trained on high-dimensional data even if the projection is based on a relatively sparse sample of the data manifold. We also find that it is preferable to use a uniformly distributed sparse sample of the data for the purpose of the generation of the low-dimensional projection. We illustrate these results considering the practical neural network approximation of a set of functions defined on high-dimensional data including real world data as well.

  2. A Parallel, Finite-Volume Algorithm for Large-Eddy Simulation of Turbulent Flows

    Science.gov (United States)

    Bui, Trong T.

    1999-01-01

    A parallel, finite-volume algorithm has been developed for large-eddy simulation (LES) of compressible turbulent flows. This algorithm includes piecewise linear least-square reconstruction, trilinear finite-element interpolation, Roe flux-difference splitting, and second-order MacCormack time marching. Parallel implementation is done using the message-passing programming model. In this paper, the numerical algorithm is described. To validate the numerical method for turbulence simulation, LES of fully developed turbulent flow in a square duct is performed for a Reynolds number of 320 based on the average friction velocity and the hydraulic diameter of the duct. Direct numerical simulation (DNS) results are available for this test case, and the accuracy of this algorithm for turbulence simulations can be ascertained by comparing the LES solutions with the DNS results. The effects of grid resolution, upwind numerical dissipation, and subgrid-scale dissipation on the accuracy of the LES are examined. Comparison with DNS results shows that the standard Roe flux-difference splitting dissipation adversely affects the accuracy of the turbulence simulation. For accurate turbulence simulations, only 3-5 percent of the standard Roe flux-difference splitting dissipation is needed.

  3. A model for steady-state large-volume plasma generation

    International Nuclear Information System (INIS)

    Uhm, H.S.; Miller, J.D.; Schneider, R.F.

    1991-01-01

    In this paper, a simple, new scheme to generate a uniform, steady-state, large-volume plasma is presented. The weakly magnetized plasma is created by direct ionization of the background gas by low-energy electrons generated from thermionic filaments. An annular arrangement of the filaments ensures a uniform plasma density in the radial direction as predicted by theory. Experiments have been performed to characterize the plasma generated in such a configuration. In order to explain the experimental observation, we develop a bulk plasma theory based on plasma transport via cross-field diffusion. As assumed in the theoretical model, the experimental measurements indicate a uniform plasma density along the axis. Both the theory and experiment indicate that the plasma density is a function of the square of the external magnetic field. The theory also predicts the plasma density to be proportional to the neutral density to the two-thirds power in agreement with the experimental data. We also observe the experimental data to agree remarkably well with theoretical prediction for a broad range of system parameters

  4. A uniform laminar air plasma plume with large volume excited by an alternating current voltage

    Science.gov (United States)

    Li, Xuechen; Bao, Wenting; Chu, Jingdi; Zhang, Panpan; Jia, Pengying

    2015-12-01

    Using a plasma jet composed of two needle electrodes, a laminar plasma plume with large volume is generated in air through an alternating current voltage excitation. Based on high-speed photography, a train of filaments is observed to propagate periodically away from their birth place along the gas flow. The laminar plume is in fact a temporal superposition of the arched filament train. The filament consists of a negative glow near the real time cathode, a positive column near the real time anode, and a Faraday dark space between them. It has been found that the propagation velocity of the filament increases with increasing the gas flow rate. Furthermore, the filament lifetime tends to follow a normal distribution (Gaussian distribution). The most probable lifetime decreases with increasing the gas flow rate or decreasing the averaged peak voltage. Results also indicate that the real time peak current decreases and the real time peak voltage increases with the propagation of the filament along the gas flow. The voltage-current curve indicates that, in every discharge cycle, the filament evolves from a Townsend discharge to a glow one and then the discharge quenches. Characteristic regions including a negative glow, a Faraday dark space, and a positive column can be discerned from the discharge filament. Furthermore, the plasma parameters such as the electron density, the vibrational temperature and the gas temperature are investigated based on the optical spectrum emitted from the laminar plume.

  5. Reduced Albumin Dosing During Large-Volume Paracentesis Is Not Associated with Adverse Clinical Outcomes.

    Science.gov (United States)

    Johnson, Kara B; Mueller, Jessica L; Simon, Tracey G; Zheng, Hui; King, Lindsay Y; Makar, Robert S; Gervais, Debra A; Chung, Raymond T

    2015-07-01

    LVP is used to manage diuretic-resistant ascites in cirrhotic patients. Albumin administration prevents complications including acute kidney injury and paracentesis-induced circulatory dysfunction, but the optimal dose is unclear. We sought to assess adherence to guidelines enacted in July 2011 at our center for reducing the albumin dose administered at large-volume paracentesis (LVP) and evaluate the cost and rate of complications of LVPs before and after guideline enactment. All LVPs performed on cirrhotic patients in our center's Department of Radiology between July 2009 and January 2014 were studied. Outcomes included adherence to guidelines, LVP complications, and administered albumin cost. Groups were compared using Student's t tests for continuous data and Chi-square or Fisher's exact tests for categorical data. A repeated measurements model accounted for patients with multiple LVPs. Of the 935 LVPs, 288 occurred before guideline implementation (group 1) and 647 occurred after (group 2). The mean dose of albumin administered was 13.7 g/L of ascites removed in group 1 versus 10.3 g/L in group 2 (p albumin administration and associated cost savings was still observed. There was no increase in LVP-related complications after guideline implementation or in the adherent group, suggesting that albumin dose can be safely reduced. Future efforts should be directed at enhancing guideline adherence and potentially further reducing albumin dosing.

  6. A simple method for the production of large volume 3D macroporous hydrogels for advanced biotechnological, medical and environmental applications

    Science.gov (United States)

    Savina, Irina N.; Ingavle, Ganesh C.; Cundy, Andrew B.; Mikhalovsky, Sergey V.

    2016-02-01

    The development of bulk, three-dimensional (3D), macroporous polymers with high permeability, large surface area and large volume is highly desirable for a range of applications in the biomedical, biotechnological and environmental areas. The experimental techniques currently used are limited to the production of small size and volume cryogel material. In this work we propose a novel, versatile, simple and reproducible method for the synthesis of large volume porous polymer hydrogels by cryogelation. By controlling the freezing process of the reagent/polymer solution, large-scale 3D macroporous gels with wide interconnected pores (up to 200 μm in diameter) and large accessible surface area have been synthesized. For the first time, macroporous gels (of up to 400 ml bulk volume) with controlled porous structure were manufactured, with potential for scale up to much larger gel dimensions. This method can be used for production of novel 3D multi-component macroporous composite materials with a uniform distribution of embedded particles. The proposed method provides better control of freezing conditions and thus overcomes existing drawbacks limiting production of large gel-based devices and matrices. The proposed method could serve as a new design concept for functional 3D macroporous gels and composites preparation for biomedical, biotechnological and environmental applications.

  7. Detection limits of the NaI(Tl) shielded HPGe spectrometer

    International Nuclear Information System (INIS)

    Bikit, I.; Slivka, J.; Krmar, M.; Durcic, Z.; Zikic, N.; Conkic, Lj.; Veskovic, M.; Anicin, I.

    1999-01-01

    The results of a detailed study of the low-level performance of a NaI(Tl) shield added to an iron shielded HPGe spectrometer are presented. Both the 'slow' and the 'fast' anticoincidence gating modes were tested, the 'slow' mode being found better suited for general low-level spectroscopy applications. In long runs the stability of the system in this mode is satisfactory. The anticoincidence action of the NaI(T1) shield lowers the integral background of the iron shielded HPGe detector in the energy range from 30 keV to 2 MeV by a factor of 6.5, and suppresses the continuum above 150 keV by a factor larger than 10

  8. Material screening with HPGe counting station for PandaX experiment

    International Nuclear Information System (INIS)

    Wang, X.; Chen, X.; Fu, C.; Ji, X.; Liu, X.; Xie, P.; Zhang, T.; Mao, Y.; Wang, S.; Wang, H.

    2016-01-01

    A gamma counting station based on high-purity germanium (HPGe) detector was set up for the material screening of the PandaX dark matter experiments in the China Jinping Underground Laboratory. Low background gamma rate of 2.6 counts/min within the energy range of 20 to 2700 keV is achieved due to the well-designed passive shield. The sentivities of the HPGe detetector reach mBq/kg level for isotopes like K, U, Th, and even better for Co and Cs, resulted from the low-background rate and the high relative detection efficiency of 175%. The structure and performance of the counting station are described in this article. Detailed counting results for the radioactivity in materials used by the PandaX dark-matter experiment are presented. The upgrading plan of the counting station is also discussed.

  9. Optimization of Compton-suppression and summing schemes for the TIGRESS HPGe detector array

    Science.gov (United States)

    Schumaker, M. A.; Svensson, C. E.; Andreoiu, C.; Andreyev, A.; Austin, R. A. E.; Ball, G. C.; Bandyopadhyay, D.; Boston, A. J.; Chakrawarthy, R. S.; Churchman, R.; Drake, T. E.; Finlay, P.; Garrett, P. E.; Grinyer, G. F.; Hackman, G.; Hyland, B.; Jones, B.; Maharaj, R.; Morton, A. C.; Pearson, C. J.; Phillips, A. A.; Sarazin, F.; Scraggs, H. C.; Smith, M. B.; Valiente-Dobón, J. J.; Waddington, J. C.; Watters, L. M.

    2007-04-01

    Methods of optimizing the performance of an array of Compton-suppressed, segmented HPGe clover detectors have been developed which rely on the physical position sensitivity of both the HPGe crystals and the Compton-suppression shields. These relatively simple analysis procedures promise to improve the precision of experiments with the TRIUMF-ISAC Gamma-Ray Escape-Suppressed Spectrometer (TIGRESS). Suppression schemes will improve the efficiency and peak-to-total ratio of TIGRESS for high γ-ray multiplicity events by taking advantage of the 20-fold segmentation of the Compton-suppression shields, while the use of different summing schemes will improve results for a wide range of experimental conditions. The benefits of these methods are compared for many γ-ray energies and multiplicities using a GEANT4 simulation, and the optimal physical configuration of the TIGRESS array under each set of conditions is determined.

  10. Performance revaluation of a N-type coaxial HPGe detector with front edges crystal using MCNPX.

    Science.gov (United States)

    Azli, Tarek; Chaoui, Zine-El-Abidine

    2015-03-01

    The MCNPX code was used to determine the efficiency of a N-type HPGe detector after two decades of operation. Accounting for the roundedness of the crystal`s front edges and an inhomogeneous description of the detector's dead layers were shown to achieve better agreement between measurements and simulation efficiency determination. The calculations were experimentally verified using point sources in the energy range from 50keV to 1400keV, and an overall uncertainty less than 2% was achieved. In order to use the detector for different matrices and geometries in radioactivity, the suggested model was validated by changing the counting geometry and by using multi-gamma disc sources. The introduced simulation approach permitted the revaluation of the performance of an HPGe detector in comparison of its initial condition, which is a useful tool for precise determination of the thickness of the inhomogeneous dead layer. Copyright © 2014 Elsevier Ltd. All rights reserved.

  11. Development results of portable gamma-radiation HPGe spectrometer with electric cooling for field applications

    International Nuclear Information System (INIS)

    Kondrat'ev, V.; Loshevich, E.; Pchelintsev, A.; Sokolov, A.; Gostilo, V.

    2015-01-01

    The paper presents development results of a portable spectrometer based on high purity germanium (HPGe spectrometer) with Stirling electric cooler for field applications. The spectrometer cryostat allows installation of HPGe coaxial detectors with efficiency up to 40% and planar detectors with sensitive area up to 3000 mm2. The detector cooling time is not more than 8 hours. Despite the mechanical vibrations due to electric cooler operation, the obtained energy resolution of the spectrometer with coaxial detector of 10% efficiency was less than 1,0 and 2,0 keV by energies 122 and 1332 keV accordingly. Miniature processor device (Android) allows control for all operation modes of the spectrometer, provides self diagnostics, initial procession, indication and spectra accumulation

  12. Determination of efficiency curves for HPGE detector in different counting geometries

    International Nuclear Information System (INIS)

    Rodrigues, Josianne L.; Kastner, Geraldo F.; Ferreira, Andrea V.

    2011-01-01

    This paper presents the first experimental results related to determination of efficiency curves for HPGe detector in different counting geometries. The detector is a GX2520 Canberra belonging to CDTN/CNEN. Efficiency curves for punctual were determined by using a certified set of gamma sources. These curves were determined for three counting geometries. Following that, efficiency curves for non punctual samples were determined by using standard solutions of radionuclides in 500 ml and 1000 ml wash bottle Marinelli

  13. Influence of Cell Phone Waves on the Performance of HPGe Detector

    International Nuclear Information System (INIS)

    Mansour, N.A.; Hassan, M.F.

    2012-01-01

    Hand phone mobile waves search systems, constructed with high resolution germanium (HPGe) detectors, are currently being installed at locations worldwide. This reflects a general desire for improved performance and a reduction in the time to make a good decision in interdiction cases. An integrated gamma-ray spectrometer, incorporating a mechanically-cooled HPGe detector, digital signal processing electronics, MCA, and communications has been developed to meet the detection and environmental needs of these systems. The HPGe detectors are designed to have good low- and medium-energy detection efficiency and excellent spectral peak resolution in order to eliminate peak overlaps and thereby remove problems by common industrial and medical radionuclides found in all types of hand phone mobile. Systems using detectors with inferior resolution, regardless of efficiency, are unable to separate the radiation signals from NORM and illicit nuclides. The absolute full-energy peak efficiency of the detector and background count-rate in the peak energy region determine the signal-to-noise ratio. Measurements presented show the impact of shielding and masking on the performance of the hand phone mobile. The results illustrate applicability of the design to a variety of monitoring situations for the detection of illicit material. In the present work we studied the effects of different types of hand phone waves on the performance of 70% HPGe X and Gamma-ray detector. The detected interference has an energy range 30-100 keV. A correction battues was estimated as a function of time verses cell phone type.The measurement quality of the measurer gamma-spectra can be corrected at low X-ray region. The effect of these waves was also studied on the performance of the main detector amplifier. The results were obtained for Etesalat, Vodafone and Mobinile stations. The introduced method can be simulated for other devices having the same interference effect.

  14. Mod 1 ICS TI Report: ICS Conversion of a 140% HPGe Detector

    Energy Technology Data Exchange (ETDEWEB)

    Bounds, John Alan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-07-05

    This report evaluates the Mod 1 ICS, an electrically cooled 140% HPGe detector. It is a custom version of the ORTEC Integrated Cooling System (ICS) modified to make it more practical for us to use in the field. Performance and operating characteristics of the Mod 1 ICS are documented, noting both pros and cons. The Mod 1 ICS is deemed a success. Recommendations for a Mod 2 ICS, a true field prototype, are provided.

  15. Evaluation of a laser scanner for large volume coordinate metrology: a comparison of results before and after factory calibration

    International Nuclear Information System (INIS)

    Ferrucci, M; Muralikrishnan, B; Sawyer, D; Phillips, S; Petrov, P; Yakovlev, Y; Astrelin, A; Milligan, S; Palmateer, J

    2014-01-01

    Large volume laser scanners are increasingly being used for a variety of dimensional metrology applications. Methods to evaluate the performance of these scanners are still under development and there are currently no documentary standards available. This paper describes the results of extensive ranging and volumetric performance tests conducted on a large volume laser scanner. The results demonstrated small but clear systematic errors that are explained in the context of a geometric error model for the instrument. The instrument was subsequently returned to the manufacturer for factory calibration. The ranging and volumetric tests were performed again and the results are compared against those obtained prior to the factory calibration. (paper)

  16. “Finite” non-Gaussianities and tensor-scalar ratio in large volume Swiss-cheese compactifications

    Science.gov (United States)

    Misra, Aalok; Shukla, Pramod

    2009-03-01

    Developing on the ideas of (Section 4 of) [A. Misra, P. Shukla, Moduli stabilization, large-volume dS minimum without anti-D3-branes, (non-)supersymmetric black hole attractors and two-parameter Swiss cheese Calabi-Yau's, Nucl. Phys. B 799 (2008) 165-198, arXiv: 0707.0105] and [A. Misra, P. Shukla, Large volume axionic Swiss-cheese inflation, Nucl. Phys. B 800 (2008) 384-400, arXiv: 0712.1260 [hep-th

  17. Incomplete charge collection in an HPGe double-sided strip detector

    International Nuclear Information System (INIS)

    Hayward, Jason; Wehe, David

    2008-01-01

    For gamma-ray detection, high-purity germanium (HPGe) has long been the standard for energy resolution, and double-sided strip detectors (DSSDs) offer the possibility of sub-millimeter position resolution. Our HPGe DSSD is 81 mm in diameter, 11-mm thick, and has 3-mm strip pitch with a gap width of 500 μm. In this work, we focus on characterizing just the interactions that occur between collecting strips. Simulation and measurement results for our HPGe DSSD show that the gap between strips is the most position-sensitive region. But, spectra collected from events that occur in and near the gaps are complicated by: (1) incomplete charge-carrier collection, or charge loss; (2) signal variance introduced by charge-carrier cloud size, orientation, and lateral spreading; and (3) the difficulty of distinguishing single interactions from multiple close interactions. Using tightly, collimated beams of monoenergetic gamma rays, the measured energy spectra at the gap center show that incomplete charge collection is significant in our detector at 356 and 662 keV, resulting in degradation of the photopeak efficiency. Additionally, close interactions are identifiable in the spectra. Thus, close interactions must be identified on an event-by-event basis in order to precisely identify gap interaction position or make charge-loss corrections at these energies. Furthermore, spectral differences are observed between anode and cathode gaps, and a possible reason for this asymmetry is proposed

  18. Performance revaluation of a N-type coaxial HPGe detector with front edges crystal using MCNPX

    International Nuclear Information System (INIS)

    Azli, Tarek; Chaoui, Zine-El-Abidine

    2015-01-01

    The MCNPX code was used to determine the efficiency of a N-type HPGe detector after two decades of operation. Accounting for the roundedness of the crystal's front edges and an inhomogeneous description of the detector's dead layers were shown to achieve better agreement between measurements and simulation efficiency determination. The calculations were experimentally verified using point sources in the energy range from 50 keV to 1400 keV, and an overall uncertainty less than 2% was achieved. In order to use the detector for different matrices and geometries in radioactivity, the suggested model was validated by changing the counting geometry and by using multi-gamma disc sources. The introduced simulation approach permitted the revaluation of the performance of an HPGe detector in comparison of its initial condition, which is a useful tool for precise determination of the thickness of the inhomogeneous dead layer. - Highlights: • Monte Carlo (MCNPX) simulation of an HPGe detector performance after more than two decades in use. • Investigating influence of detector rounded front edges of crystal. • Achieving good matching between Monte Carlo simulation and experiments by inhomogeneous description of detector dead layers

  19. Determination Performance Of Gamma Spectrometry Co-Axial HPGE Detector In Radiochemistry And Environment Group, Nuclear Malaysia

    International Nuclear Information System (INIS)

    Mei-Woo, Y.

    2014-01-01

    Gamma Spectrometry System is used to measure qualitatively and quantitatively a gamma emitting radionuclide. The accuracy of the measurement very much depends on the performance specifications of the HPGe detectors. From this study it found that all the seven co-axial HPGe detectors in Radiochemistry and Environment Group, Nuclear Malaysia are in good working conditions base on the verification of performance specifications namely Resolution, Peak Shape, Peak-to-Compton ratio and Relative Efficiency against the warranted value from the manufacturers. (author)

  20. Large parallel volumes of finite and compact sets in d-dimensional Euclidean space

    DEFF Research Database (Denmark)

    Kampf, Jürgen; Kiderlen, Markus

    The r-parallel volume V (Cr) of a compact subset C in d-dimensional Euclidean space is the volume of the set Cr of all points of Euclidean distance at most r > 0 from C. According to Steiner’s formula, V (Cr) is a polynomial in r when C is convex. For finite sets C satisfying a certain geometric...

  1. Type IIB orientifolds, D-brane instantons and the large volume scenario

    Energy Technology Data Exchange (ETDEWEB)

    Plauschinn, Erik

    2009-07-28

    This thesis is concerned with a branch of research in String Theory called String Phenomenology which aims for a better understanding of the connection between String Theory and Particle Physics. In particular, in this work we cover three topics which are important in order to establish this connection. The first topic is about String Theory model building in the context of so-called type IIB orientifolds with orientifold three- and seven-planes. After giving a brief overview, we work out in detail an important consistency condition for String Theory constructions, the so-called tadpole cancellation condition, and we verify explicitly that chiral anomalies are cancelled via the generalised Green-Schwarz mechanism. The second topic is concerned with so-called D-brane instantons which are nonperturbative effects in type II String Theory constructions. We recall the instanton calculus for such configurations, we derive the so-called A eck-Dine-Seiberg superpotential in String Theory and we develop an important constraint, a chiral zero-mode constraint, for instanton contributions in the presence of a realistic Particle Physics sector. The third topic is about moduli stabilisation in type IIB string compactifications. More concretely, we review the so-called KKLT as well as Large Volume Scenario, and we construct and study a model for the latter scenario where the constraint mentioned above has been taken into account explicitly. Although the three topics studied in this thesis are slightly different in nature, there is nevertheless a complex interplay between them with many interrelations. In order to uncover these connections, a detailed study of each individual subject has been performed which has led to new results such as the chiral zero-mode constraint. (orig.)

  2. Addressing challenges in bar-code scanning of large-volume infusion bags.

    Science.gov (United States)

    Raman, Kirthana; Heelon, Mark; Kerr, Gary; Higgins, Thomas L

    2011-08-01

    A hospital pharmacy's efforts to identify and address challenges with bedside scanning of bar codes on large-volume parenteral (LVP) infusion bags are described. Bar-code-assisted medication administration (BCMA) has been shown to reduce medication errors and improve patient safety. After the pilot implementation of a BCMA system and point-of-care scanning procedures at a medical center's intensive care unit, it was noted that nurses' attempted bedside scans of certain LVP bags for product identification purposes often were not successful. An investigation and root-cause analysis, including observation of nurses' scanning technique by a multidisciplinary team, determined that the scanning failures stemmed from the placement of two bar-code imprints-one with the product identification code and another, larger imprint with the expiration date and lot number-adjacently on the LVP bags. The nursing staff was educated on a modified scanning technique, which resulted in significantly improved success rates in the scanning of the most commonly used LVP bags. Representatives of the LVP bag manufacturer met with hospital staff to discuss the problem and corrective measures. As part of a subsequent infusion bag redesign, the manufacturer discontinued the use of the bar-code imprint implicated in the scanning failures. Failures in scanning LVP bags were traced to problematic placement of bar-code imprints on the bags. Interdisciplinary collaboration, consultation with the bag manufacturer, and education of the nursing and pharmacy staff resulted in a reduction in scanning failures and the manufacturer's removal of one of the bar codes from its LVP bags.

  3. Type IIB orientifolds, D-brane instantons and the large volume scenario

    International Nuclear Information System (INIS)

    Plauschinn, Erik

    2009-01-01

    This thesis is concerned with a branch of research in String Theory called String Phenomenology which aims for a better understanding of the connection between String Theory and Particle Physics. In particular, in this work we cover three topics which are important in order to establish this connection. The first topic is about String Theory model building in the context of so-called type IIB orientifolds with orientifold three- and seven-planes. After giving a brief overview, we work out in detail an important consistency condition for String Theory constructions, the so-called tadpole cancellation condition, and we verify explicitly that chiral anomalies are cancelled via the generalised Green-Schwarz mechanism. The second topic is concerned with so-called D-brane instantons which are nonperturbative effects in type II String Theory constructions. We recall the instanton calculus for such configurations, we derive the so-called A eck-Dine-Seiberg superpotential in String Theory and we develop an important constraint, a chiral zero-mode constraint, for instanton contributions in the presence of a realistic Particle Physics sector. The third topic is about moduli stabilisation in type IIB string compactifications. More concretely, we review the so-called KKLT as well as Large Volume Scenario, and we construct and study a model for the latter scenario where the constraint mentioned above has been taken into account explicitly. Although the three topics studied in this thesis are slightly different in nature, there is nevertheless a complex interplay between them with many interrelations. In order to uncover these connections, a detailed study of each individual subject has been performed which has led to new results such as the chiral zero-mode constraint. (orig.)

  4. A pomegranate-inspired nanoscale design for large-volume-change lithium battery anodes

    Science.gov (United States)

    Liu, Nian; Lu, Zhenda; Zhao, Jie; McDowell, Matthew T.; Lee, Hyun-Wook; Zhao, Wenting; Cui, Yi

    2014-03-01

    Silicon is an attractive material for anodes in energy storage devices, because it has ten times the theoretical capacity of its state-of-the-art carbonaceous counterpart. Silicon anodes can be used both in traditional lithium-ion batteries and in more recent Li-O2 and Li-S batteries as a replacement for the dendrite-forming lithium metal anodes. The main challenges associated with silicon anodes are structural degradation and instability of the solid-electrolyte interphase caused by the large volume change (~300%) during cycling, the occurrence of side reactions with the electrolyte, and the low volumetric capacity when the material size is reduced to a nanometre scale. Here, we propose a hierarchical structured silicon anode that tackles all three of these problems. Our design is inspired by the structure of a pomegranate, where single silicon nanoparticles are encapsulated by a conductive carbon layer that leaves enough room for expansion and contraction following lithiation and delithiation. An ensemble of these hybrid nanoparticles is then encapsulated by a thicker carbon layer in micrometre-size pouches to act as an electrolyte barrier. As a result of this hierarchical arrangement, the solid-electrolyte interphase remains stable and spatially confined, resulting in superior cyclability (97% capacity retention after 1,000 cycles). In addition, the microstructures lower the electrode-electrolyte contact area, resulting in high Coulombic efficiency (99.87%) and volumetric capacity (1,270 mAh cm-3), and the cycling remains stable even when the areal capacity is increased to the level of commercial lithium-ion batteries (3.7 mAh cm-2).

  5. Morphological pyramids in multiresolution MIP rendering of large volume data : Survey and new results

    NARCIS (Netherlands)

    Roerdink, J.B.T.M.

    We survey and extend nonlinear signal decompositions based on morphological pyramids, and their application to multiresolution maximum intensity projection (MIP) volume rendering with progressive refinement and perfect reconstruction. The structure of the resulting multiresolution rendering

  6. Effect of crowd size on patient volume at a large, multipurpose, indoor stadium.

    Science.gov (United States)

    De Lorenzo, R A; Gray, B C; Bennett, P C; Lamparella, V J

    1989-01-01

    A prediction of patient volume expected at "mass gatherings" is desirable in order to provide optimal on-site emergency medical care. While several methods of predicting patient loads have been suggested, a reliable technique has not been established. This study examines the frequency of medical emergencies at the Syracuse University Carrier Dome, a 50,500-seat indoor stadium. Patient volume and level of care at collegiate basketball and football games as well as rock concerts, over a 7-year period were examined and tabulated. This information was analyzed using simple regression and nonparametric statistical methods to determine level of correlation between crowd size and patient volume. These analyses demonstrated no statistically significant increase in patient volume for increasing crowd size for basketball and football events. There was a small but statistically significant increase in patient volume for increasing crowd size for concerts. A comparison of similar crowd size for each of the three events showed that patient frequency is greatest for concerts and smallest for basketball. The study suggests that crowd size alone has only a minor influence on patient volume at any given event. Structuring medical services based solely on expected crowd size and not considering other influences such as event type and duration may give poor results.

  7. Real-time numerical processing for HPGE detectors signals

    International Nuclear Information System (INIS)

    Eric Barat; Thomas Dautremer; Laurent Laribiere; Jean Christophe Trama

    2006-01-01

    Full text of publication follows: Concerning the gamma spectrometry, technology progresses in the processor field makes very conceivable and attractive executing complex real-time digital process. Only some simplified and rigid treatments can be find in the market up to now. Indeed, the historical solution used for 50 years consists of performing a so-called 'cusp' filtering and disturbing the optimal shape in order to shrink and/or truncate it. This tuning largely determined by the input count rate (ICR) the user expects to measure is then a compromise between the resolution and the throughput. Because it is not possible to tune it for each pulse, that is a kind of 'leveling down' which is made: the energy of each pulse is not as well estimated as it could be. The new approach proposed here avoids totally this restricting hand tuning. The innovation lies in the modelling of the shot-noise signal as a Jump Markov Linear System. The jump is the occurrence of a pulse in the signal. From this model, we developed an algorithm which makes possible the on-line estimation of the energies without having to temporally enlarge the pulses as the cusp filter does. The algorithm first determines whether there is a pulse or not at each time, then conditionally to this information, it performs an optimal Kalman smoother. Thanks to this global optimization, this allows us to dramatically increase the compromise throughput versus resolution, gaining an important factor on a commercial device concerning the admissible ICR (more than 1 million counts per second admissible). A huge advantage of the absence of hand tuning is that the system accepts fluctuating ICR. To validate the concept we built a real time demonstrator. First, our equipment is composed of an electronic stage which prepared the signal coming from the preamplifier of the detector and optimized the signal-to-noise ratio. Then the signal is sampled at 10 MHz and the powerful of two Pentium running at 3 GHz is enough to

  8. Dosimetric Comparison of Split Field and Fixed Jaw Techniques for Large IMRT Target Volumes in the Head and Neck

    International Nuclear Information System (INIS)

    Srivastava, Shiv P.; Das, Indra J.; Kumar, Arvind; Johnstone, Peter A.S.

    2011-01-01

    Some treatment planning systems (TPSs), when used for large-field (>14 cm) intensity-modulated radiation therapy (IMRT), create split fields that produce excessive multiple-leaf collimator segments, match-line dose inhomogeneity, and higher treatment times than nonsplit fields. A new method using a fixed-jaw technique (FJT) forces the jaw to stay at a fixed position during optimization and is proposed to reduce problems associated with split fields. Dosimetric comparisons between split-field technique (SFT) and FJT used for IMRT treatment is presented. Five patients with head and neck malignancies and regional target volumes were studied and compared with both techniques. Treatment planning was performed on an Eclipse TPS using beam data generated for Varian 2100C linear accelerator. A standard beam arrangement consisting of nine coplanar fields, equally spaced, was used in both techniques. Institutional dose-volume constraints used in head and neck cancer were kept the same for both techniques. The dosimetric coverage for the target volumes between SFT and FJT for head and neck IMRT plan is identical within ±1% up to 90% dose. Similarly, the organs at risk (OARs) have dose-volume coverage nearly identical for all patients. When the total monitor unit (MU) and segments were analyzed, SFT produces statistically significant higher segments (17.3 ± 6.3%) and higher MU (13.7 ± 4.4%) than the FJT. There is no match line in FJT and hence dose uniformity in the target volume is superior to the SFT. Dosimetrically, SFT and FJT are similar for dose-volume coverage; however, the FJT method provides better logistics, lower MU, shorter treatment time, and better dose uniformity. The number of segments and MU also has been correlated with the whole body radiation dose with long-term complications. Thus, FJT should be the preferred option over SFT for large target volumes.

  9. Process Improvement to Enhance Quality in a Large Volume Labor and Birth Unit.

    Science.gov (United States)

    Bell, Ashley M; Bohannon, Jessica; Porthouse, Lisa; Thompson, Heather; Vago, Tony

    using the Lean process, frontline clinicians identified areas that needed improvement, developed and implemented successful strategies that addressed each gap, and enhanced the quality and safety of care for a large volume perinatal service.

  10. State of art data acquisition system for large volume plasma device

    International Nuclear Information System (INIS)

    Sugandhi, Ritesh; Srivastava, Pankaj; Sanyasi, Amulya Kumar; Srivastav, Prabhakar; Awasthi, Lalit Mohan; Mattoo, Shiban Krishna; Parmar, Vijay; Makadia, Keyur; Patel, Ishan; Shah, Sandeep

    2015-01-01

    The Large volume plasma device (LVPD) is a cylindrical device (ϕ = 2m, L = 3m) dedicated for carrying out investigations on plasma physics problems ranging from excitation of whistler structures to plasma turbulence especially, exploring the linear and nonlinear aspects of electron temperature gradient(ETG) driven turbulence, plasma transport over the entire cross section of LVPD. The machine operates in a pulsed mode with repetition cycle of 1 Hz and acquisition pulse length of duration of 15 ms, presently, LVPD has VXI data acquisition system but this is now in phasing out mode because of non-functioning of its various amplifier stages, expandability and unavailability of service support. The VXI system has limited capabilities to meet new experimental requirements in terms of numbers of channel (16), bit resolutions (8 bit), record length (30K points) and calibration support. Recently, integration of new acquisition system for simultaneous sampling of 40 channels of data, collected over multiple time scales with high speed is successfully demonstrated, by configuring latest available hardware and in-house developed software solutions. The operational feasibility provided by LabVIEW platform is not only for operating DAQ system but also for providing controls to various subsystems associated with the device. The new system is based on PXI express instrumentation bus and supersedes the existing VXI based data acquisition system in terms of instrumentation capabilities. This system has capability to measure 32 signals at 60 MHz sampling frequency and 8 signals with 1.25 GHz with 10 bit and 12 bit resolution capability for amplitude measurements. The PXI based system successfully addresses and demonstrate the issues concerning high channel count, high speed data streaming and multiple I/O modules synchronization. The system consists of chassis (NI 1085), 4 high sampling digitizers (NI 5105), 2 very high sampling digitizers (NI 5162), data streaming RAID drive (NI

  11. Temperature monitoring in large volume spread footing foundations: case study "Parque da Cidade" - São Paulo

    Directory of Open Access Journals (Sweden)

    D. Couto

    Full Text Available ABSTRACT In recent years, the construction of foundation elements from large-volume reinforced concrete is becoming increasingly common. This implies a potential increase in the risk of cracks of thermal origin, due to the heat of hydration of cement. Under these circumstances, these concrete elements need to be treated using the mass concrete theory, widespread in dam construction, but little used when designing buildings. This paper aims to present a case study about the procedures and problems involved in the construction of a spread footing with a volume of approximately 800m³ designed for the foundation of a shopping center in São Paulo, Brazil.

  12. Forced transport of thermal energy in magmatic and phreatomagmatic large volume ignimbrites: Paleomagnetic evidence from the Colli Albani volcano, Italy

    Science.gov (United States)

    Trolese, Matteo; Giordano, Guido; Cifelli, Francesca; Winkler, Aldo; Mattei, Massimo

    2017-11-01

    Few studies have detailed the thermal architecture of large-volume pyroclastic density current deposits, although such work has a clear importance for understanding the dynamics of eruptions of this magnitude. Here we examine the temperature of emplacement of large-volume caldera-forming ignimbrites related to magmatic and phreatomagmatic eruptions at the Colli Albani volcano, Italy, by using thermal remanent magnetization analysis on both lithic and juvenile clasts. Results show that all the magmatic ignimbrites were deposited at high temperature, between the maximum blocking temperature of the magnetic carrier (600-630 °C) and the glass transition temperature (about 710 °C). Temperature estimations for the phreatomagmatic ignimbrite range between 200 and 400 °C, with most of the clasts emplaced between 200 and 320 °C. Because all the investigated ignimbrites, magmatic and phreatomagmatic, share similar magma composition, volume and mobility, we attribute the temperature difference to magma-water interaction, highlighting its pronounced impact on thermal dissipation, even in large-volume eruptions. The homogeneity of the deposit temperature of each ignimbrite across its areal extent, which is maintained across topographic barriers, suggests that these systems are thermodynamically isolated from the external environment for several tens of kilometers. Based on these findings, we propose that these large-volume ignimbrites are dominated by the mass flux, which forces the lateral transport of mass, momentum, and thermal energy for distances up to tens of kilometers away from the vent. We conclude that spatial variation of the emplacement temperature can be used as a proxy for determining the degree of forced-convection flow.

  13. Resolution, efficiency and stability of HPGe detector operating in a magnetic field at various gamma-ray energies

    International Nuclear Information System (INIS)

    Szymanska, K.; Achenbach, P.; Agnello, M.; Botta, E.; Bracco, A.; Bressani, T.; Camera, F.; Cederwall, B.; Feliciello, A.; Ferro, F.; Gerl, J.; Iazzi, F.; Kavatsyuk, M.; Kojouharov, I.; Pochodzalla, J.; Raciti, G.; Saito, T.R.; Sanchez Lorente, A.; Tegner, P.-E.; Wieland, O.

    2008-01-01

    The use of High Purity Germanium detectors (HPGe) has been planned in some future experiments of hadronic physics. The crystals will be located close to large spectrometers where the magnetic fringing field will not be negligible and their performances might change. Moreover high precision is required in these experiments. The contribution of magnetic field presence and long term measurements is unique. In this paper the results of systematic measurements of the resolution, stability and efficiency of a crystal operating inside a magnetic field of 0.8 T, using radioactive sources in the energy range from 0.08 to 1.33 MeV, are reported. The measurements have been repeated during several months in order to test if any permanent damage occurred. The resolution at 1.117 and 1.332 MeV gamma-rays from a 60 Co source has been measured at different magnetic fields in the range of 0-0.8 T and the results are compared with the previous data

  14. Systems and methods for the detection of low-level harmful substances in a large volume of fluid

    Science.gov (United States)

    Carpenter, Michael V.; Roybal, Lyle G.; Lindquist, Alan; Gallardo, Vincente

    2016-03-15

    A method and device for the detection of low-level harmful substances in a large volume of fluid comprising using a concentrator system to produce a retentate and analyzing the retentate for the presence of at least one harmful substance. The concentrator system performs a method comprising pumping at least 10 liters of fluid from a sample source through a filter. While pumping, the concentrator system diverts retentate from the filter into a container. The concentrator system also recirculates at least part of the retentate in the container again through the filter. The concentrator system controls the speed of the pump with a control system thereby maintaining a fluid pressure less than 25 psi during the pumping of the fluid; monitors the quantity of retentate within the container with a control system, and maintains a reduced volume level of retentate and a target volume of retentate.

  15. Gamma-ray Full Spectrum Analysis for Environmental Radioactivity by HPGe Detector

    Science.gov (United States)

    Jeong, Meeyoung; Lee, Kyeong Beom; Kim, Kyeong Ja; Lee, Min-Kie; Han, Ju-Bong

    2014-12-01

    Odyssey, one of the NASA¡¯s Mars exploration program and SELENE (Kaguya), a Japanese lunar orbiting spacecraft have a payload of Gamma-Ray Spectrometer (GRS) for analyzing radioactive chemical elements of the atmosphere and the surface. In these days, gamma-ray spectroscopy with a High-Purity Germanium (HPGe) detector has been widely used for the activity measurements of natural radionuclides contained in the soil of the Earth. The energy spectra obtained by the HPGe detectors have been generally analyzed by means of the Window Analysis (WA) method. In this method, activity concentrations are determined by using the net counts of energy window around individual peaks. Meanwhile, an alternative method, the so-called Full Spectrum Analysis (FSA) method uses count numbers not only from full-absorption peaks but from the contributions of Compton scattering due to gamma-rays. Consequently, while it takes a substantial time to obtain a statistically significant result in the WA method, the FSA method requires a much shorter time to reach the same level of the statistical significance. This study shows the validation results of FSA method. We have compared the concentration of radioactivity of 40K, 232Th and 238U in the soil measured by the WA method and the FSA method, respectively. The gamma-ray spectrum of reference materials (RGU and RGTh, KCl) and soil samples were measured by the 120% HPGe detector with cosmic muon veto detector. According to the comparison result of activity concentrations between the FSA and the WA, we could conclude that FSA method is validated against the WA method. This study implies that the FSA method can be used in a harsh measurement environment, such as the gamma-ray measurement in the Moon, in which the level of statistical significance is usually required in a much shorter data acquisition time than the WA method.

  16. Efficiency transfer using the GEANT4 code of CERN for HPGe gamma spectrometry.

    Science.gov (United States)

    Chagren, S; Tekaya, M Ben; Reguigui, N; Gharbi, F

    2016-01-01

    In this work we apply the GEANT4 code of CERN to calculate the peak efficiency in High Pure Germanium (HPGe) gamma spectrometry using three different procedures. The first is a direct calculation. The second corresponds to the usual case of efficiency transfer between two different configurations at constant emission energy assuming a reference point detection configuration and the third, a new procedure, consists on the transfer of the peak efficiency between two detection configurations emitting the gamma ray in different energies assuming a "virtual" reference point detection configuration. No pre-optimization of the detector geometrical characteristics was performed before the transfer to test the ability of the efficiency transfer to reduce the effect of the ignorance on their real magnitude on the quality of the transferred efficiency. The obtained and measured efficiencies were found in good agreement for the two investigated methods of efficiency transfer. The obtained agreement proves that Monte Carlo method and especially the GEANT4 code constitute an efficient tool to obtain accurate detection efficiency values. The second investigated efficiency transfer procedure is useful to calibrate the HPGe gamma detector for any emission energy value for a voluminous source using one point source detection efficiency emitting in a different energy as a reference efficiency. The calculations preformed in this work were applied to the measurement exercise of the EUROMET428 project. A measurement exercise where an evaluation of the full energy peak efficiencies in the energy range 60-2000 keV for a typical coaxial p-type HpGe detector and several types of source configuration: point sources located at various distances from the detector and a cylindrical box containing three matrices was performed. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. Gamma-ray Full Spectrum Analysis for Environmental Radioactivity by HPGe Detector

    Directory of Open Access Journals (Sweden)

    Meeyoung Jeong

    2014-12-01

    Full Text Available Odyssey, one of the NASA’s Mars exploration program and SELENE (Kaguya, a Japanese lunar orbiting spacecraft have a payload of Gamma-Ray Spectrometer (GRS for analyzing radioactive chemical elements of the atmosphere and the surface. In these days, gamma-ray spectroscopy with a High-Purity Germanium (HPGe detector has been widely used for the activity measurements of natural radionuclides contained in the soil of the Earth. The energy spectra obtained by the HPGe detectors have been generally analyzed by means of the Window Analysis (WA method. In this method, activity concentrations are determined by using the net counts of energy window around individual peaks. Meanwhile, an alternative method, the so-called Full Spectrum Analysis (FSA method uses count numbers not only from full-absorption peaks but from the contributions of Compton scattering due to gamma-rays. Consequently, while it takes a substantial time to obtain a statistically significant result in the WA method, the FSA method requires a much shorter time to reach the same level of the statistical significance. This study shows the validation results of FSA method. We have compared the concentration of radioactivity of 40K, 232Th and 238U in the soil measured by the WA method and the FSA method, respectively. The gamma-ray spectrum of reference materials (RGU and RGTh, KCl and soil samples were measured by the 120% HPGe detector with cosmic muon veto detector. According to the comparison result of activity concentrations between the FSA and the WA, we could conclude that FSA method is validated against the WA method. This study implies that the FSA method can be used in a harsh measurement environment, such as the gamma-ray measurement in the Moon, in which the level of statistical significance is usually required in a much shorter data acquisition time than the WA method.

  18. Strategy of HPGe screening measurements in the SuperNEMO experiment

    Energy Technology Data Exchange (ETDEWEB)

    Perrot, Frédéric [Université de Bordeaux, Centre d' Etudes Nucléaires de Bordeaux Gradignan, UMR 5797, Chemin du Solarium, Le Haut-Vigneau, BP120, F-33175 Gradignan, France and CNRS/IN2P3, Centre d' Etudes Nucléaires de Bordeaux Gradignan, UMR 5797 (France); Collaboration: SuperNEMO Collaboration

    2013-08-08

    SuperNEMO is a double beta decay experiment that will use a tracko-calorimeter technique. The goal is to reach a sensitivity of T{sub 1/2}(0ν)>10{sup 26} y corresponding to an effective Majorana neutrino mass of 0.04-0.11 eV with 100 kg of {sup 82}Se. The general strategy of the HPGe screening measurements is described for the materials of the SuperNEMO demonstrator, regarding their radiopurity and their location. The two platforms, PRISNA and LSM, used for this screening are also briefly described.

  19. Calibration and application of a HPGe gamma spectrometer for in-situ measurements

    International Nuclear Information System (INIS)

    Xiao Xuefu; Yue Qingyu

    1992-02-01

    The principle and methods of the calibration for an in-situ γ spectrometer are introduced. The calibration for a portable HPGe γ spectrometer has been completed. The N f /A(peak count rate per unit activity in soil) and N f /D(peak count rate per unit absorbed dose rate in the air) are listed. The uncertainties of the calibration factors are estimated. The in-situ measurements have been carried out in surroundings near the nuclear facilities and the data are compared with those measured by other methods

  20. Interference of escape peaks from HPGe(LEPS) detector on characteristic X-ray spectrum

    International Nuclear Information System (INIS)

    Pimjun, S.

    1992-01-01

    Analyses for concentrations of iron, niobium and tantalum in valuable ores by X-ray fluorescence analysis (XRF) method, characteristic X-rays of Fe was interfered by the escape peak of Nb from HPGe(LEPS) detector. To solve this problem, normalizations of Nb spectra with the computer program were used. The result analyzed for Fe, Nb and Ta concentration in the sample, compared to those with the neutron activation analysis (NAA) method, the corresponding errors about 5% were obtained satisfactorily. This method of XRF can be applied efficiently instead of NAA method during the reactor shut-down for a long period

  1. Fitted curve parameters for the efficiency of a coaxial HPGe Detector

    International Nuclear Information System (INIS)

    Supian Samat

    1996-01-01

    Using Ngraph software, the parameters of various functions were determined by least squares analysis of fits to experimental efficiencies , ε sub f of a coaxial HPGe detector for gamma rays in the energy range 59 keV to 1836 keV. When these parameters had been determined, their reliability was tested by the calculated goodness-of-fit parameter χ sup 2 sub cal. It is shown that the function, ln ε sub f = Σ sup n sub j=0 a sub j (ln E/E sub 0) sup j , where n=3, gives satisfactory results

  2. Tow efficiency correction functions of source self-absorption of an HPGe detector

    International Nuclear Information System (INIS)

    Gao Zheng; Ma Yusheng; Luo Jianghua; Chen Luning

    2007-01-01

    The efficiency correction function of source absorption of an HPGe γ detector is determined by experiment in energy range from 59.5 keV to 1408 keV and density range from 0.3 g/cm 3 to 2.0 g/cm 3 . Fit Polynomial and fit Sigmoidal are compared. The results show that fit Sigmoidal is better than fit polynomial, and the detection efficiency at any points of energy and density could be conveniently calculated with it in calibrated range. (authors)

  3. Efficiency transfer using the GEANT4 code of CERN for HPGe gamma spectrometry

    International Nuclear Information System (INIS)

    Chagren, S.; Tekaya, M.Ben; Reguigui, N.; Gharbi, F.

    2016-01-01

    In this work we apply the GEANT4 code of CERN to calculate the peak efficiency in High Pure Germanium (HPGe) gamma spectrometry using three different procedures. The first is a direct calculation. The second corresponds to the usual case of efficiency transfer between two different configurations at constant emission energy assuming a reference point detection configuration and the third, a new procedure, consists on the transfer of the peak efficiency between two detection configurations emitting the gamma ray in different energies assuming a “virtual” reference point detection configuration. No pre-optimization of the detector geometrical characteristics was performed before the transfer to test the ability of the efficiency transfer to reduce the effect of the ignorance on their real magnitude on the quality of the transferred efficiency. The obtained and measured efficiencies were found in good agreement for the two investigated methods of efficiency transfer. The obtained agreement proves that Monte Carlo method and especially the GEANT4 code constitute an efficient tool to obtain accurate detection efficiency values. The second investigated efficiency transfer procedure is useful to calibrate the HPGe gamma detector for any emission energy value for a voluminous source using one point source detection efficiency emitting in a different energy as a reference efficiency. The calculations preformed in this work were applied to the measurement exercise of the EUROMET428 project. A measurement exercise where an evaluation of the full energy peak efficiencies in the energy range 60–2000 keV for a typical coaxial p-type HpGe detector and several types of source configuration: point sources located at various distances from the detector and a cylindrical box containing three matrices was performed. - Highlights: • The GEANT4 code of CERN has been used to transfer the peak efficiency from point to points and voluminous detection configurations in HPGe gamma

  4. An immunomagnetic separator for concentration of pathogenic micro-organisms from large volume samples

    International Nuclear Information System (INIS)

    Rotariu, Ovidiu; Ogden, Iain D.; MacRae, Marion; Badescu, Vasile; Strachan, Norval J.C.

    2005-01-01

    The standard method of immunomagnetic separation of pathogenic bacteria from food and environmental matrices processes 1 ml volumes. Pathogens present at low levels ( 50 ml). Preliminary results show that between 70 and 113 times more Escherchia coli O157 are recovered compared with the standard 1 ml method

  5. Chromatographic lipophilicity determination using large volume injections of the solvents non-miscible with the mobile phase.

    Science.gov (United States)

    Sârbu, Costel; Naşcu-Briciu, Rodica Domnica; Casoni, Dorina; Kot-Wasik, Agata; Wasik, Andrzej; Namieśnik, Jacek

    2012-11-30

    A new perspective in the lipophilicity evaluation through RP-HPLC is permitted by analysis of the retention factor (k) obtained by injecting large volumes of test samples prepared in solvents immiscible with mobile phase. The experiment is carried out on representative groups of compounds with increased toxicity (mycotoxins and alkaloids) and amines with important biological activity (naturally occurring monoamine compounds and related drugs), which are covering a large interval of lipophilicity. The stock solution of each compound was prepared in hexane and the used mobile phases were mixtures of methanol or acetonitrile and water, in suited volume ratio. The injected volume was between 10 and 100 μL, while the used stationary phases were RP-18 and RP-8. On both reverse stationary phases the retention factors were linearly decreasing while the injection volume was increasing. In all cases, the linear models were highly statistically significant. On the basis of the obtained results new lipophilicity indices were purposed and discussed. The developed lipophilicity indices and the computationally expressed ones are correlated at a high level of statistical significance. Copyright © 2012 Elsevier B.V. All rights reserved.

  6. A Monte-Carlo code for neutron efficiency calculations for large volume Gd-loaded liquid scintillation detectors

    Energy Technology Data Exchange (ETDEWEB)

    Trzcinski, A.; Zwieglinski, B. [Soltan Inst. for Nuclear Studies, Warsaw (Poland); Lynen, U. [Gesellschaft fuer Schwerionenforschung mbH, Darmstadt (Germany); Pochodzalla, J. [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany)

    1998-10-01

    This paper reports on a Monte-Carlo program, MSX, developed to evaluate the performance of large-volume, Gd-loaded liquid scintillation detectors used in neutron multiplicity measurements. The results of simulations are presented for the detector intended to count neutrons emitted by the excited target residue in coincidence with the charged products of the projectile fragmentation following relativistic heavy-ion collisions. The latter products could be detected with the ALADIN magnetic spectrometer at GSI-Darmstadt. (orig.) 61 refs.

  7. Considerations in reviewing the waste volume reduction program in a large utility

    International Nuclear Information System (INIS)

    Kohout, R.; Calzolari, L.M.

    1987-01-01

    A program is underway at Ontario Hydro to establish a desirable future scheme for central processing/volume reduction of solid radioactive Low-Level Wastes (LLW) prior to their placement into the centralized storage, and in the future into a disposal facility. The approach being investigated is to furnish the current Waste Volume Reduction Facility (WVRF) with state-of-art processes, reclassify the waste categories and segregate the wastes such that each volume reduction (VR) process is then applied where it would be most effective. The ''optimized'' approach is then compared with other, specific schemes, which basically differ in that each scheme omits one of the major VR processes, thus allowing the next most effective process to take over its role. Each scheme is assessed quantitatively from the viewpoint of cost and VR effectiveness, and qualitatively from the viewpoint of resultant waste form. The economic assessments take into consideration the long term (20 year) impact of selected VR schemes on the overall waste management cost, including construction and operation of the storage facility. This paper highlights the overall study, includes the major results, and identifies aspects that need to be addressed in the selection of a desirable combination of VR processes in absence of knowledge of future waste disposal costs

  8. In situ prompt gamma-ray activation analysis of water pollutants using a shallow 252Cf-HPGe probe

    International Nuclear Information System (INIS)

    Chung Chien; Tseng Tzucheng

    1988-01-01

    A shallow 252 Cf-HPGe probe used for in situ prompt γ-ray activation of water pollutants is described. A 2.7 μg 252 Cf neutron source and a 10% HPGe detector are inserted into a waterproof stainless steel probe, which is designed to be submerged and recovered in field operation. A laboratory test is performed to obtain the neutron flux distribution and prompt γ-ray contribution to the HPGe detector counts from around the submerged probe. The concentrations of toxic cadmium and chlorine in water are determined in the prompt γ-ray spectrum. The detection limit of industrial pollutants and some improvements of the current design are discussed. (orig.)

  9. The influence of anisotropic electron drift velocity on the signal shapes of closed-end HPGe detectors

    CERN Document Server

    Mihailescu, L; Lieder, R M; Brands, H; Jaeger, H

    2000-01-01

    This study is concerned with the anisotropy of the electron drift velocity in germanium crystals at high electric fields and low temperature, and its influence on the charge collection process in n-type, high-purity germanium (HPGe) detectors of closed-end, coaxial geometry. The electron trajectories inside HPGe detectors are simulated using a phenomenological model to calculate the dependence of the drift velocity on the angle between the electric field and the crystal orientation. The resulting induced currents and pulse shapes for a given detector geometry and preamplifier bandwidth are compared to experiment. Experimentally, the dependence of the pulse shapes on the conductivity anisotropy in closed-end HPGe detectors was observed. The experimental data on pulse shapes were obtained by sampling preamplifier signals of an encapsulated, hexaconical EUROBALL detector, which was irradiated by collimated sup 2 sup 2 Na and sup 2 sup 4 sup 1 Am sources. The crystal orientation was measured by neutron reflection...

  10. Optimization of the n-type HPGe detector parameters to theoretical determination of efficiency curves

    International Nuclear Information System (INIS)

    Rodriguez-Rodriguez, A.; Correa-Alfonso, C.M.; Lopez-Pino, N.; Padilla-Cabal, F.; D'Alessandro, K.; Corrales, Y.; Garcia-Alvarez, J. A.; Perez-Mellor, A.; Baly-Gil, L.; Machado, A.

    2011-01-01

    A highly detailed characterization of a 130 cm 3 n-type HPGe detector, employed in low - background gamma spectrometry measurements, was done. Precise measured data and several Monte Carlo (MC) calculations have been combined to optimize the detector parameters. HPGe crystal location inside the Aluminum end-cap as well as its dimensions, including the borehole radius and height, were determined from frontal and lateral scans. Additionally, X-ray radiography and Computed Axial Tomography (CT) studies were carried out to complement the information about detector features. Using seven calibrated point sources ( 241 Am, 133 Ba, 57,60 Co, 137 Cs, 22 Na and 152 Eu), photo-peak efficiency curves at three different source - detector distances (SDD) were obtained. Taking into account the experimental values, an optimization procedure by means of MC simulations (MCNPX 2.6 code) were performed. MC efficiency curves were calculated specifying the optimized detector parameters in the MCNPX input files. Efficiency calculation results agree with empirical data, showing relative deviations lesser 10%. (Author)

  11. SmartPET: Applying HPGe and pulse shape analysis to small-animal PET

    Energy Technology Data Exchange (ETDEWEB)

    Cooper, R.J. [Department of Physics, University of Liverpool (United Kingdom)], E-mail: rjc@ns.ph.liv.ac.uk; Boston, A.J.; Boston, H.C.; Cresswell, J.R.; Grint, A.N.; Mather, A.R.; Nolan, P.J.; Scraggs, D.P.; Turk, G. [Department of Physics, University of Liverpool (United Kingdom); Hall, C.J.; Lazarus, I. [CCLRC Daresbury Laboratory, Warrington, Cheshire (United Kingdom); Berry, A.; Beveridge, T.; Gillam, J.; Lewis, R.A. [School of Physics and Materials Engineering, Monash University, Melbourne (Australia)

    2007-08-21

    The SmartPET project is the development of a prototype small-animal imaging system based on the use of Hyperpure Germanium (HPGe) detectors. The use of digital electronics and application of Pulse Shape Analysis (PSA) techniques provide fine spatial resolution, while the excellent intrinsic energy resolution of HPGe detectors makes the system ideal for multi-nuclide imaging. As a result, the SmartPET system has the potential to function as a dual modality imager, operating as a dual-head Positron Emission Tomography (PET) camera or in a Compton Camera configuration for Single Photon Emission Computed Tomography (SPECT) imaging. In this paper, we discuss how the use of simple PSA techniques greatly improves the position sensitivity of the detector yielding improved spatial resolution in reconstructed images. The PSA methods presented have been validated by comparison to data from high-precision scanning of the detectors. Results from this analysis are presented along with initial images from the SmartPET system, which demonstrates the impact of these techniques on PET images.

  12. Performance evaluation of portable HPGe with in situ object counting system (ISOCS) in direct thyroid radiobioassay

    Energy Technology Data Exchange (ETDEWEB)

    Park, Min Seok; Kwon, Tae Eun; Pak, Min Jung; Park, Se Young; Ha, Wi Ho; Jin, Young Woo [National Radiation Emergency Medical Center (NREMC), Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of)

    2016-12-15

    To evaluate the internal radiation dose, various methods are required to identify and quantify radionuclides in human body. Internal contamination monitoring related with the radioiodine is generally performed by direct radiobioassay which used scintillator-based thyroid monitor. Recently, a semiconductor material such as high purity germanium (HPGe) has been used for in vivo radiobioassay. In this study, broad energy germanium (BEGe) which was a kind of HPGe was used for thyroid radiobioassay. BEGe shows good performance in the radiobioassay due to its high energy resolution. In Situ Object Counting System (ISOCS) was the efficiency calibration software developed by Canberra Industries. The efficiency calibration with this system was performed by the Monte Carlo method. It was useful method as alternative method of conventional calibration. The purpose of this study is to evaluate the performance of measuring radioiodine by means of ISOCS which is equipped with the portable HPG(Falcon 5000, Canberra Industries) in direct thyroid radiobioassay. The ISOCS software ensured compliance with the performance criteria in the radioiodine measurement. These results of participating in intercomparison program indicated the feasibility of applying ISOCS software to direct thyroid radiobioassay with more convenient procedure.

  13. Development of an underground HPGe array facility for ultra low radioactivity measurements

    Energy Technology Data Exchange (ETDEWEB)

    Sala, E.; Kang, W. G.; Kim, Y. D.; Lee, M. H.; Leonard, D. S. [Center for Underground Physics - Institute for Basic Science, Daejeon (Korea, Republic of); Hahn, I. S.; Kim, G. W.; Park, S. Y. [Ewha Womans University, Physics Department, Seoul (Korea, Republic of)

    2015-08-17

    Low Level Counting techniques using low background facilities are continuously under development to increase the possible sensitivity needed for rare physics events experiments. The CUP (Center for Underground Physics) group of IBS is developing, in collaboration with Canberra, a ultra low background instrument composed of two arrays facing each other with 7 HPGe detectors each. The low radioactive background of each detector has been evaluated and improved by the material selection of the detector components. Samples of all the building materials have been provided by the manufacturer and the contaminations had been measured using an optimized low background 100% HPGe with a dedicated shielding. The evaluation of the intrinsic background has been performed using MonteCarlo simulations and considering the contribution of each material with the measured contamination. To further reduce the background, the instrument will be placed in the new underground laboratory at YangYang exploiting the 700m mountain coverage and radon-free air supplying system. The array has been designed to perform various Ultra Low background measurements; the sensitivity we are expecting will allow not only low level measurements of Ra and Th contaminations in Copper or other usually pure materials, but also the search for rare decays. In particular some possible candidates and configurations to detect the 0νECEC (for example {sup 106}Cd and {sup 156}Dy) and rare β decays ({sup 96}Zr, {sup 180m}Ta , etc ) are under study.

  14. Evaluation of HPGe spectrometric devices in monitoring the level of radioactive contamination in metallurgical industry

    Energy Technology Data Exchange (ETDEWEB)

    Petrucci, A., E-mail: andrea.petrucci@enea.it [ENEA – Istituto Nazionale di Metrologia delle Radiazione Ionizzanti, Rome (Italy); Arnold, D.; Burda, O. [PTB – Physikalisch-Technische Bundesanstalt, Bundesallee 100, 38116 Braunschweig (Germany); De Felice, P. [ENEA – Istituto Nazionale di Metrologia delle Radiazione Ionizzanti, Rome (Italy); Garcia-Toraño, E.; Mejuto, M.; Peyres, V. [CIEMAT – Laboratorio de Metrologia de Radiaciones Ionizantes, Avda. Complutense 40, 28040 Madrid (Spain); Šolc, J. [CMI – Czech Metrology Institute, Radiova 1a, 102 00 Praha 10 (Czech Republic); Vodenik, B. [IJS – Laboratory for Radioactivity Measurements, Institute Jožef Stefan, Jamova 39, 1000 Ljubljana Slovenia (Slovenia)

    2015-10-11

    This paper presents the results of the tests of High Purity Germanium (HPGe) based gamma spectrometers employed for radioactivity control carried out on a daily basis in steel factories. This new application of this type of detector is part of the Joint Research Project (JRP) MetroMETAL supported by the European Metrology Research Programme (EMRP). The final purpose of the project was the improvement and standardisation of the measurement methods and systems for the control of radioactivity of recycled metal scraps at the beginning of the working process and for the certification of the absence of any radioactive contamination above the clearance levels (IAEA-TECDOC-8S5) in final steel products, Clearance levels for radionuclides in solid materials: application of exemption principles). Two prototypes based on HPGe detectors were designed and assembled to suit the needs of steel mills which had been examined previously. The evaluation of the two prototypes, carried out at three steel factories with standard sources of {sup 60}Co, {sup 137}Cs, {sup 192}Ir, {sup 226}Ra and {sup 241}Am in three different matrices (slag, fume dust and cast steel) and with samples provided on-site by the factories, was successful. The measurements proved the superiority of the prototypes over the scintillation detectors now commonly used regarding energy resolution and multi-nuclide identification capability. The detection limits were assessed and are presented as well.

  15. Scoping measurements of radionuclides in L Lake with an underwater HPGe detector

    International Nuclear Information System (INIS)

    Dunn, D.L.; Win, W.G.; Bresnahan, P.J.

    1996-01-01

    This study of L Lake was conducted to determine whether the distribution of man-made radiation levels had changed from the time preceding the filling of the newly created lake in 1985. Overflight gamma measurements by EG ampersand G in 1985 mapped the man-made radiation levels, indicating that significant levels were only detected from former stream beds that were to be covered by the lake. the present scoping gamma measurements were consistent with these earlier findings, indicating no major evidence of movement of the radioactivity. These results will be available to guide decisions concerning future plans for the lake. Gamma-emitting radionuclides of L Lake were examined in situ with an underwater HPGe detector and further studied by retrieving various sediment samples for analysis by HPGe gamma spectrometry in the Underground Counting Facility. The predominant man-made radionuclide detected was 137 Cs; it had about 100 times greater activity than 60 Co, which was the only other man-made radionuclide that was detected above trace levels

  16. Paul Scherrer Institute Scientific Report 1998. Volume VI: Large Research Facilities

    International Nuclear Information System (INIS)

    Bauer, Guenter; Bercher, Renate; Buechli, Carmen; Foroughi, Fereydoun; Meyer, Rosa

    1999-01-01

    The department GFA (Grossforschungsanlagen, Large Research Facilities) has been established in October 1998 and its main duty is operation, maintenance and development of the PSI accelerators, the spallation neutron source and the beam transport systems for pions and muons. A large effort of this group concerns the planning and co-ordination of the assembly of the Swiss Light Source (SLS). (author)

  17. Very Large Data Volumes Analysis of Collaborative Systems with Finite Number of States

    Science.gov (United States)

    Ivan, Ion; Ciurea, Cristian; Pavel, Sorin

    2010-01-01

    The collaborative system with finite number of states is defined. A very large database is structured. Operations on large databases are identified. Repetitive procedures for collaborative systems operations are derived. The efficiency of such procedures is analyzed. (Contains 6 tables, 5 footnotes and 3 figures.)

  18. Resuscitation of a Polytraumatized Patient with Large Volume Crystalloid-Colloid Infusions – Correlation Between Global and Regional Hemodynamics: Case Report

    OpenAIRE

    Lončarić-Katušin, Mirjana; Belavić, Matija; Žunić, Josip; Gučanin, Snježana; Žilić, Antonio; Korać, Želimir

    2010-01-01

    Aggressive large volume resuscitation is obligatory to achieve necessary tissue oxygenation. An adequate venous preload normalizes global hemodynamics and avoids multiorgan failure (MOF) and death in patients with multiple injuries. Large volume resuscitation is associated with complications in minimally monitored patients. A properly guided resuscitation procedure will finally prevent MOF and patient death. Transpulmonary thermodilution technique and gastric tonometry are used in venous prel...

  19. Environmental gamma radiation monitoring system with a large volume air ionization chamber

    International Nuclear Information System (INIS)

    Duftschmid, K.E.; Strachotinsky, C.; Witzani, J.

    1986-01-01

    An improved environmental monitoring system has been designed and tested consisting of an ionization chamber with 120 l sensitive volume, operated at atmospheric pressure, and a commercial electrometer amplifier with digital voltmeter. The system is controlled by a desk calculator with printer for automated operation and calculation of dose and doserate. The ionization chamber provides superior dosimetric performance as compared to usual GM-counters and high pressure chambers. The system has been field-tested during the 'European Intercomparison Programme for Environmental Monitoring Instruments' organized by the Commission of the European Communities. (Author)

  20. Large-Scale Context-Aware Volume Navigation using Dynamic Insets

    KAUST Repository

    Al-Awami, Ali

    2012-07-01

    Latest developments in electron microscopy (EM) technology produce high resolution images that enable neuro-scientists to identify and put together the complex neural connections in a nervous system. However, because of the massive size and underlying complexity of this kind of data, processing, navigation and analysis suffer drastically in terms of time and effort. In this work, we propose the use of state-of- the-art navigation techniques, such as dynamic insets, built on a peta-scale volume visualization framework to provide focus and context-awareness to help neuro-scientists in their mission to analyze, reconstruct, navigate and explore EM neuroscience data.

  1. Paul Scherrer Institute Scientific and Technical Report 1999. Volume VI: Large Research Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Foroughi, Fereydoun; Bercher, Renate; Buechli, Carmen; Meyer, Rosa [eds.

    2000-07-01

    The department GFA (Grossforschungsanlagen, Large Research Facilities) has been established in October 1998. Its main duty is operation, maintenance and development of the PSI accelerators, the spallation neutron source and the beam transport systems for pions and muons. A large effort of this group concerns the planning and co-ordination of new projects like e.g. the assembly of the synchrotron light source (SLS), design studies of a new proton therapy facility, the ultracold neutron source and a new intensive secondary beam line for low energy muons. A large fraction of this report is devoted to research especially in the field of materials Science. The studies include large scale molecular dynamics computer simulations on the elastic and plastic behavior of nanostructured metals, complemented by experimental mechanical testing using micro-indentation and miniaturized tensile testing, as well as microstructural characterisation and strain field mapping of metallic coatings and thin ceramic layers, the latter done with synchrotron radiation.

  2. Paul Scherrer Institute Scientific and Technical Report 1999. Volume VI: Large Research Facilities

    International Nuclear Information System (INIS)

    Foroughi, Fereydoun; Bercher, Renate; Buechli, Carmen; Meyer, Rosa

    2000-01-01

    The department GFA (Grossforschungsanlagen, Large Research Facilities) has been established in October 1998. Its main duty is operation, maintenance and development of the PSI accelerators, the spallation neutron source and the beam transport systems for pions and muons. A large effort of this group concerns the planning and co-ordination of new projects like e.g. the assembly of the synchrotron light source (SLS), design studies of a new proton therapy facility, the ultracold neutron source and a new intensive secondary beam line for low energy muons. A large fraction of this report is devoted to research especially in the field of materials Science. The studies include large scale molecular dynamics computer simulations on the elastic and plastic behavior of nanostructured metals, complemented by experimental mechanical testing using micro-indentation and miniaturized tensile testing, as well as microstructural characterisation and strain field mapping of metallic coatings and thin ceramic layers, the latter done with synchrotron radiation

  3. Methods for fitting of efficiency curves obtained by means of HPGe gamma rays spectrometers; Metodos de ajuste de curvas de eficiencia obtidas por meio de espectrometros de HPGe

    Energy Technology Data Exchange (ETDEWEB)

    Cardoso, Vanderlei

    2002-07-01

    The present work describes a few methodologies developed for fitting efficiency curves obtained by means of a HPGe gamma-ray spectrometer. The interpolated values were determined by simple polynomial fitting and polynomial fitting between the ratio of experimental peak efficiency and total efficiency, calculated by Monte Carlo technique, as a function of gamma-ray energy. Moreover, non-linear fitting has been performed using a segmented polynomial function and applying the Gauss-Marquardt method. For the peak area obtainment different methodologies were developed in order to estimate the background area under the peak. This information was obtained by numerical integration or by using analytical functions associated to the background. One non-calibrated radioactive source has been included in the curve efficiency in order to provide additional calibration points. As a by-product, it was possible to determine the activity of this non-calibrated source. For all fittings developed in the present work the covariance matrix methodology was used, which is an essential procedure in order to give a complete description of the partial uncertainties involved. (author)

  4. Paul Scherrer Institute Scientific Report 1998. Volume VI: Large Research Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Bauer, Guenter; Bercher, Renate; Buechli, Carmen; Foroughi, Fereydoun; Meyer, Rosa [eds.

    1999-09-01

    The department GFA (Grossforschungsanlagen, Large Research Facilities) has been established in October 1998 and its main duty is operation, maintenance and development of the PSI accelerators, the spallation neutron source and the beam transport systems for pions and muons. A large effort of this group concerns the planning and co-ordination of the assembly of the Swiss Light Source (SLS). (author) figs., tabs., refs.

  5. Nuclear waste calorimeter for very large drums with 385 litres sample volume

    Energy Technology Data Exchange (ETDEWEB)

    Jossens, G.; Mathonat, C. [SETARAM Instrumentation, Caluire (France); Bachelet, F. [CEA Valduc, Is sur Tille (France)

    2015-03-15

    Calorimetry is a very precise and well adapted tool for the classification of drums containing nuclear waste material depending on their level of activities (low, medium, high). A new calorimeter has been developed by SETARAM Instrumentation and the CEA Valduc in France. This new calorimeter is designed for drums having a volume bigger than 100 liters. It guarantees high operator safety by optimizing drum handling and air circulation for cooling, and optimized software for direct measurement of the quantity of nuclear material. The LVC1380 calorimeter makes it possible to work over the range 10 to 3000 mW, which corresponds to approximately 0.03 to 10 g of tritium or 3 to 955 g of {sup 241}Pu in a volume up to 385 liters. This calorimeter is based on the heat flow measurement using Peltier elements which surround the drum in the 3 dimensions and therefore measure all the heat coming from the radioactive stuff whatever its position inside the drum. Calorimeter's insulating layers constitute a thermal barrier designed to filter disturbances until they represent less than 0.001 Celsius degrees and to eliminate long term disturbances associated, for example, with laboratory temperature variations between day and night. A calibration device based on Joule effect has also been designed. Measurement time has been optimized but remains long compared with other methods of measurement such as gamma spectrometry but its main asset is to have a good accuracy for low level activities.

  6. Non-equilibrium Inertial Separation Array for High-throughput, Large-volume Blood Fractionation.

    Science.gov (United States)

    Mutlu, Baris R; Smith, Kyle C; Edd, Jon F; Nadar, Priyanka; Dlamini, Mcolisi; Kapur, Ravi; Toner, Mehmet

    2017-08-30

    Microfluidic blood processing is used in a range of applications from cancer therapeutics to infectious disease diagnostics. As these applications are being translated to clinical use, processing larger volumes of blood in shorter timescales with high-reliability and robustness is becoming a pressing need. In this work, we report a scaled, label-free cell separation mechanism called non-equilibrium inertial separation array (NISA). The NISA mechanism consists of an array of islands that exert a passive inertial lift force on proximate cells, thus enabling gentler manipulation of the cells without the need of physical contact. As the cells follow their size-based, deterministic path to their equilibrium positions, a preset fraction of the flow is siphoned to separate the smaller cells from the main flow. The NISA device was used to fractionate 400 mL of whole blood in less than 3 hours, and produce an ultrapure buffy coat (96.6% white blood cell yield, 0.0059% red blood cell carryover) by processing whole blood at 3 mL/min, or ∼300 million cells/second. This device presents a feasible alternative for fractionating blood for transfusion, cellular therapy and blood-based diagnostics, and could significantly improve the sensitivity of rare cell isolation devices by increasing the processed whole blood volume.

  7. Gamma-ray multiplicity measurement of the spontaneous fission decay of 252Cf in a segmented HPGe/BGO detector array

    Energy Technology Data Exchange (ETDEWEB)

    Bleuel, D L; Bernstein, L A; Burke, J T; Gibelin, J; Heffner, M D; Mintz, J; Norman, E B; Phair, L; Scielzo, N D; Sheets, S A; Snyderman, N J; Stoyer, M A; Wiedeking, M

    2008-04-23

    Coincident {gamma} rays from a {sup 252}Cf source were measured using an array of six segmented high-purity germanium (HPGe) Clover detectors each enclosed by 16 bismuth-germanate (BGO) detectors. The detectors were arranged in a cubic pattern around a 1 {micro}Ci {sup 252}Cf source to cover a large solid angle for {gamma}-ray measurement with a reasonable reconstruction of the multiplicity. Neutron multiplicity was determined in certain cases by identifying the prompt {gamma} rays from individual fission fragment pairs. Multiplicity distributions from previous experiments and theoretical models were convolved with the response function of the array and compared to the present results. These results suggest a {gamma}-ray multiplicity spectrum broader than previous measurements and models, and provide no evidence of correlation with neutron multiplicity.

  8. Construction and Start-up of a Large-Volume Thermostat for Dielectric-Constant Gas Thermometry

    Science.gov (United States)

    Merlone, A.; Moro, F.; Zandt, T.; Gaiser, C.; Fellmuth, B.

    2010-07-01

    A liquid-bath thermostat with a volume of about 800 L was designed to provide a suitable thermal environment for a dielectric-constant gas thermometer (DCGT) in the range from the triple point of mercury to the melting point of gallium. In the article, results obtained with the unique, huge thermostat without the DCGT measuring chamber are reported to demonstrate the capability of controlling the temperature of very large systems at a metrological level. First tests showed that the bath together with its temperature controller provide a temperature variation of less than ±0.5mK peak-to-peak. This temperature instability could be maintained over a period of several days. In the central working volume (diameter—500mm, height—650mm), in which the vacuum chamber containing the measuring system of the DCGT will be placed later, the temperature inhomogeneity has been demonstrated to be also well below 1mK.

  9. Glass-covering of large building volumes. An interdisciplinary evaluation of a shopping centre

    Energy Technology Data Exchange (ETDEWEB)

    Oeman, R [Royal Inst. of Tech., Stockholm (Sweden). Dept. of Building Technology

    1994-12-31

    Systematized experiences of the function of large glass-covered spaces related to shopping centres, hotels, office buildings etc. are still relatively limited. With the glazed pedestrian precincts of the rebuilt Skaerholmen Centre in Stockholm as the main object of interdisciplinary studies, the aim of this thesis is to provide additional knowledge of large glass-covered spaces (atrium buildings). The studies comprises thermal comfort, temperature conditions, ventilation, energy balance, humidity - mycology, acoustics, operation - maintenance - durability and sociology. To sum up, it is clear that in the Scandinavian climate there is every likelihood of large glass-covered spaces in the public places functioning well from a technical as well as a social point of view. The energy consumption on heating the whole complex, based on theoretical calculations and measurement, is shown to have been reduced by the order of 10%. figs., tabs., refs.

  10. Large-volume heat storage tank made of GFK; Grosswaermespeichertank aus GFK

    Energy Technology Data Exchange (ETDEWEB)

    Buehl, J.; Schultheis, P. [Technische Univ. Ilmenau (Germany). Fachgebiet Technische Thermodynamik

    1998-12-31

    The Technical University of Ilmenau, the company Verbundwerkstoff- und Kunststoffanwendungstechnik Schoenbrunn, the Institute for Aerospace and Light-weight construction of Dresden University with its approved testing facilities for plastics and the Institute for Construction Engineering in Berlin and several other institutions co-operated since 1996 in developing a concept for a series of long-term heat storage tanks up to 6,000 cubic metres storage volume made of plastic (GFK components) with a combined thermal insulation. A model tank (sandwich body with proportional thermal insulation layer and selected mixed laminates) with a volume of 1.5 cubic metres was built and installed in November 1996. The tank has been continuously operated at various test levels. The experiment proves the longevity of the materials used. (orig.) [Deutsch] In Zusammenarbeit der TU Ilmenau mit der Fa. Verbundwerkstoff - und Kunststoffanwendungstechnik Schoenbrunn und dem Institut fuer Luftfahrttechnik und Leichtbau Dresden, seiner akkredierten Pruefstelle fuer Kunststoffe, in Abstimmung mit dem Institut fuer Bautechnik Berlin und weiteren Einrichtungen und Partnern wird seit 1996 an einem Konzept fuer eine Typenreihe Langzeitwaermespeicher bis vorerst 6.000 m{sup 3} Speichervolumen aus Kunststoff (GFK-Komponenten) und kombinierter integrierter thermischer Isolation gearbeitet. Im Vorfeld dieser Entwicklung wurde auf der Basis vorausgewaehlter Materialien und Kompositionen ein Musterspeicher (ein Sandwich - Modellkoerper mit proportionaler Waermedaemmschicht sowie ausgewaehlten Mischlaminaten) mit einem Speichervolumen von 1,5 m{sup 3} realisiert. Dieser Musterspeicher wurde im November 1996 installiert und wird seither kontinuierlich in den entsprechenden Erprobungsstufen betrieben. Der Nachweis der Langlebigkeit der eingesetzten Materialien wurde experimentell erbracht. (orig.)

  11. A large volume striped bass egg incubation chamber: design and comparison with a traditional method

    Science.gov (United States)

    Harper, C.J.

    2009-01-01

    I conducted a comparative study of a new jar design (experimental chamber) with a standard egg incubation vessel (McDonald jar). Experimental chambers measured 0.4 m in diameter by 1.3 m in height and had a volume of 200 L. McDonald hatching jars measured 16 cm in diameter by 45 cm in height and had a volume of 6 L. Post-hatch survival was estimated at 48, 96 and 144 h. Stocking rates resulted in an average egg density of 21.9 eggs ml-1 (range = 21.6 – 22.1) for McDonald jars and 10.9 eggs ml-1 (range = 7.0 – 16.8) for experimental chambers. I was unable to detect an effect of container type on survival to 48, 96 or 144 h. At 144 h striped bass fry survival averaged 37.3% for McDonald jars and 34.2% for experimental chambers. Survival among replicates was significantly different. Survival of striped bass significantly decreased between 96 and 144 h. Mean survival among replicates ranged from 12.4 to 57.3%. I was unable to detect an effect of initial stocking density on survival. Experimental jars allow for incubation of a larger number of eggs in a much smaller space. As hatchery production is often limited by space or water supply, experimental chambers offer an alternative to extending spawning activities, thereby reducing manpower and cost. However, the increase in the number of eggs per rearing container does increase the risk associated with catastrophic loss of a production unit. I conclude the experimental chamber is suitable for striped bass egg incubation.

  12. The BREAST-V: a unifying predictive formula for volume assessment in small, medium, and large breasts.

    Science.gov (United States)

    Longo, Benedetto; Farcomeni, Alessio; Ferri, Germano; Campanale, Antonella; Sorotos, Micheal; Santanelli, Fabio

    2013-07-01

    Breast volume assessment enhances preoperative planning of both aesthetic and reconstructive procedures, helping the surgeon in the decision-making process of shaping the breast. Numerous methods of breast size determination are currently reported but are limited by methodologic flaws and variable estimations. The authors aimed to develop a unifying predictive formula for volume assessment in small to large breasts based on anthropomorphic values. Ten anthropomorphic breast measurements and direct volumes of 108 mastectomy specimens from 88 women were collected prospectively. The authors performed a multivariate regression to build the optimal model for development of the predictive formula. The final model was then internally validated. A previously published formula was used as a reference. Mean (±SD) breast weight was 527.9 ± 227.6 g (range, 150 to 1250 g). After model selection, sternal notch-to-nipple, inframammary fold-to-nipple, and inframammary fold-to-fold projection distances emerged as the most important predictors. The resulting formula (the BREAST-V) showed an adjusted R of 0.73. The estimated expected absolute error on new breasts is 89.7 g (95 percent CI, 62.4 to 119.1 g) and the expected relative error is 18.4 percent (95 percent CI, 12.9 to 24.3 percent). Application of reference formula on the sample yielded worse predictions than those derived by the formula, showing an R of 0.55. The BREAST-V is a reliable tool for predicting small to large breast volumes accurately for use as a complementary device in surgeon evaluation. An app entitled BREAST-V for both iOS and Android devices is currently available for free download in the Apple App Store and Google Play Store. Diagnostic, II.

  13. VOLUMETRIC LEAK DETECTION IN LARGE UNDERGROUND STORAGE TANKS - VOLUME II: APPENDICES A-E

    Science.gov (United States)

    The program of experiments conducted at Griffiss Air Force Base was devised to expand the understanding of large underground storage tank behavior as it impacts the performance of volumetric leak detection testing. The report addresses three important questions about testing the ...

  14. Prognostic value of defining the systemic tumor volume with FDG-PET in diffuse large b cell lymphoma

    International Nuclear Information System (INIS)

    Byun, Byung Hyun; Lim, Sang Moo; Cheon, Gi Jeong; Choi, Chang Woon; Kang, Hye Jin; Na, Im Il; Ryoo, Baek Yeol; Yang, Sung Hyun

    2007-01-01

    We measured the systemic tumor volume using FDG-PET in patients with diffuse large B cell lymphoma (DLBL). We also investigated its prognostic role, and compared it with that of other prognostic factors. FDG PET was performed in 38 newly diagnosed DLBL patients (20 men, 18 women, age 55.715.1 years) at pre-treatment of chemotherapy. Clinical staging of lymphoma was evaluated by Ann Arbor system. On each FDG PET scan, we acquired volume of interest (VOl) at the cut-off value of SUV=2.5 in every measurable tumor by the automatic edge detection software. According to the VOI, we measured the metabolic volume and mean SUV, and estimated volume-activity indexes (SUV Vol) as mean SUV times metabolic volume. And then, we calculated the summed metabolic volume (VOLsum) and summed SUV Vol (SUV Volsum) in every FDG PET scan. Maximum SUV of involved lesion (SUVmax) was also acquired on each FDG PET scan. Time to treatment failure (TTF) was compared among VOLsum (median), SUV Volsum (median), SUVmax (median), clinical stage, gender, age, LDH, and performance status-assigned response designations by Kaplan-Meier survival analysis. Initial stages of DLBL patients were stage I in 4, II in 14, III in 15, and IV in 4 by Ann Arbor system. Median follow up period was 15.5months, and estimated mean TTF was 22.3 months. Univariate analysis demonstrated that TTF is statistically significantly reduced in those with high VOLsum (>215.1cm2, p=0.004), high SUV Volsum (>1577.5, p=0.003), and increased LDH (p=0.036). TTF did not correlate with SUVmax (p=0.571), clinical stage (p=0.194), gender (p=0.549), and age (p=0.128), and performance status =2 (p=0.074). Multivariate analysis using VOLsum, SUV Volsum, LDH, and performance status demonstrated no statistically significant predictor of TTF (p>0.05). Systemic tumor volume measurement using FDG-PET is suggestive to be the significant prognostic factor in patients with DLBL

  15. Ultra-large scale AFM of lipid droplet arrays: investigating the ink transfer volume in dip pen nanolithography

    International Nuclear Information System (INIS)

    Förste, Alexander; Pfirrmann, Marco; Sachs, Johannes; Gröger, Roland; Walheim, Stefan; Brinkmann, Falko; Hirtz, Michael; Fuchs, Harald; Schimmel, Thomas

    2015-01-01

    There are only few quantitative studies commenting on the writing process in dip-pen nanolithography with lipids. Lipids are important carrier ink molecules for the delivery of bio-functional patters in bio-nanotechnology. In order to better understand and control the writing process, more information on the transfer of lipid material from the tip to the substrate is needed. The dependence of the transferred ink volume on the dwell time of the tip on the substrate was investigated by topography measurements with an atomic force microscope (AFM) that is characterized by an ultra-large scan range of 800 × 800 μm 2 . For this purpose arrays of dots of the phospholipid1,2-dioleoyl-sn-glycero-3-phosphocholine were written onto planar glass substrates and the resulting pattern was imaged by large scan area AFM. Two writing regimes were identified, characterized of either a steady decline or a constant ink volume transfer per dot feature. For the steady state ink transfer, a linear relationship between the dwell time and the dot volume was determined, which is characterized by a flow rate of about 16 femtoliters per second. A dependence of the ink transport from the length of pauses before and in between writing the structures was observed and should be taken into account during pattern design when aiming at best writing homogeneity. The ultra-large scan range of the utilized AFM allowed for a simultaneous study of the entire preparation area of almost 1 mm 2 , yielding good statistic results. (paper)

  16. Soft SUSY breaking parameters and RG running of squark and slepton masses in large volume Swiss Cheese compactifications

    International Nuclear Information System (INIS)

    Misra, Aalok; Shukla, Pramod

    2010-01-01

    We consider type IIB large volume compactifications involving orientifolds of the Swiss Cheese Calabi-Yau WCP 4 [1,1,1,6,9] with a single mobile space-time filling D3-brane and stacks of D7-branes wrapping the 'big' divisor Σ B (as opposed to the 'small' divisor usually done in the literature thus far) as well as supporting D7-brane fluxes. After reviewing our proposal of (Misra and Shukla, 2010) for resolving a long-standing tension between large volume cosmology and phenomenology pertaining to obtaining a 10 12 GeV gravitino in the inflationary era and a TeV gravitino in the present era, and summarizing our results of (Misra and Shukla, 2010) on soft supersymmetry breaking terms and open-string moduli masses, we discuss the one-loop RG running of the squark and slepton masses in mSUGRA-like models (using the running of the gaugino masses) to the EW scale in the large volume limit. Phenomenological constraints and some of the calculated soft SUSY parameters identify the D7-brane Wilson line moduli as the first two generations/families of squarks and sleptons and the D3-brane (restricted to the big divisor) position moduli as the two Higgses for MSSM-like models at TeV scale. We also discuss how the obtained open-string/matter moduli make it easier to impose FCNC constraints, as well as RG flow of off-diagonal squark mass(-squared) matrix elements.

  17. Soft SUSY breaking parameters and RG running of squark and slepton masses in large volume Swiss Cheese compactifications

    Science.gov (United States)

    Misra, Aalok; Shukla, Pramod

    2010-03-01

    We consider type IIB large volume compactifications involving orientifolds of the Swiss Cheese Calabi-Yau WCP[1,1,1,6,9] with a single mobile space-time filling D3-brane and stacks of D7-branes wrapping the “big” divisor ΣB (as opposed to the “small” divisor usually done in the literature thus far) as well as supporting D7-brane fluxes. After reviewing our proposal of [1] (Misra and Shukla, 2010) for resolving a long-standing tension between large volume cosmology and phenomenology pertaining to obtaining a 10 GeV gravitino in the inflationary era and a TeV gravitino in the present era, and summarizing our results of [1] (Misra and Shukla, 2010) on soft supersymmetry breaking terms and open-string moduli masses, we discuss the one-loop RG running of the squark and slepton masses in mSUGRA-like models (using the running of the gaugino masses) to the EW scale in the large volume limit. Phenomenological constraints and some of the calculated soft SUSY parameters identify the D7-brane Wilson line moduli as the first two generations/families of squarks and sleptons and the D3-brane (restricted to the big divisor) position moduli as the two Higgses for MSSM-like models at TeV scale. We also discuss how the obtained open-string/matter moduli make it easier to impose FCNC constraints, as well as RG flow of off-diagonal squark mass(-squared) matrix elements.

  18. the Preliminary Research Based on Seismic Signals Generated by Hutubi Transmitting Seismic Station with One Large-volume Airgun Array

    Science.gov (United States)

    Wang, Q.; Su, J.; Wei, Y.; Zhang, W.; Wang, H.; Wang, B.; Ji, Z.

    2017-12-01

    For studying the subsurface structure and its subtle changes, we built the Hutubi transmitting seismic station with one large-volume airgun array at one artificial water pool in the northern segment of Tianshan mountain, where earthquakes occurred frequently. The airgun array consists of six airguns with every airgun capacity of 2000in3, and the artificial water pool with the top diameter of 100m, bottom diameter of 20m and the depth of 18m.We started the regular excitation experiment with the large-volume airgun source every week since June, 2013. Using seismic signals geneated by the Hutubi airgun source, we made the preliminary research on the airgun source, waveform characteristics and the subsurface velocity changes in the northern Tiansh mountain. The results are as follows: The seismic signal exited by the airgun source is characteristic of low-frequency ,and the dominant frequency is in the range of 2 6Hz. The Hutubi transmitting seismic station can continuously generate long-distance detectable and highly repeatable signals, and the correlation coefficient of sigals is greater than 0.95; and the longest propagation distance arrives to 380km, in addition, the 5000-shot stacked sigal using the phase weighted stack technique can be identified in the station, which is about 1300km from the Hutubi transmitting seismic station. Hutubi large-volume airgun source is fitted to detect and monitor the regional-scale subsurface stress state. Applying correlation test method, we measured weak subsurface velocity changes in the northern Tianshan mountain, and found that the several stations, which are within 150km from the the Hutubi transmitting seismic station, appeared 0.1 0.2% relative velocity changes before the Hutubi MS6.2 earthquake on Dec.8, 2016.

  19. Percutaneous Image-Guided Cryoablation of Challenging Mediastinal Lesions Using Large-Volume Hydrodissection: Technical Considerations and Outcomes

    Energy Technology Data Exchange (ETDEWEB)

    Garnon, Julien, E-mail: juliengarnon@gmail.com; Koch, Guillaume, E-mail: Guillaume.koch@gmail.com; Caudrelier, Jean, E-mail: caudjean@yahoo.fr [University Hospital of Strasbourg, Department of Interventional Radiology (France); Ramamurthy, Nitin, E-mail: Nitin-ramamurthy@hotmail.com [Norfolk and Norwich University Hospital, Department of Radiology (United Kingdom); Rao, Pramod, E-mail: pramodrao@me.com [University of Strasbourg, ICube (France); Tsoumakidou, Georgia, E-mail: Georgia.tsoumakidou@chru-strasbourg.fr; Cazzato, Roberto Luigi, E-mail: cazzatorobertoluigi@gmail.com; Gangi, Afshin, E-mail: Afshin.gangi@chru-strasbourg.fr [University Hospital of Strasbourg, Department of Interventional Radiology (France)

    2016-11-15

    ObjectiveThis study was designed to describe the technique of percutaneous image-guided cryoablation with large-volume hydrodissection for the treatment of challenging mediastinal lesions.MethodsBetween March 2014 and June 2015, three patients (mean age 62.7 years) with four neoplastic anterior mediastinal lesions underwent five cryoablation procedures using large-volume hydrodissection. Procedures were performed under general anaesthesia using CT guidance. Lesion characteristics, hydrodissection and cryoablation data, technical success, complications, and clinical outcomes were assessed using retrospective chart review.ResultsLesions (mean size 2.7 cm; range 2–4.3 cm) were in contact with great vessels (n = 13), trachea (n = 3), and mediastinal nerves (n = 6). Hydrodissection was performed intercostally (n = 4), suprasternally (n = 2), transsternally (n = 1), or via the sternoclavicular joint (n = 1) using 1–3 spinal needles over 13.4 (range 7–26) minutes; 450 ml of dilute contrast was injected (range 300–600 ml) and increased mean lesion-collateral structure distance from 1.9 to 7.7 mm. Vulnerable mediastinal nerves were identified in four of five procedures. Technical success was 100 %, with one immediate complication (recurrent laryngeal nerve injury). Mean follow-up period was 15 months. One lesion demonstrated residual disease on restaging PET-CT and was retreated to achieve complete ablation. At last follow-up, two patients remained disease-free, and one patient developed distant disease after 1 year without local recurrence.ConclusionsCryoablation using large-volume hydrodissection is a feasible technique, enabling safe and effective treatment of challenging mediastinal lesions.

  20. Ultra-large scale AFM of lipid droplet arrays: investigating the ink transfer volume in dip pen nanolithography

    Science.gov (United States)

    Förste, Alexander; Pfirrmann, Marco; Sachs, Johannes; Gröger, Roland; Walheim, Stefan; Brinkmann, Falko; Hirtz, Michael; Fuchs, Harald; Schimmel, Thomas

    2015-05-01

    There are only few quantitative studies commenting on the writing process in dip-pen nanolithography with lipids. Lipids are important carrier ink molecules for the delivery of bio-functional patters in bio-nanotechnology. In order to better understand and control the writing process, more information on the transfer of lipid material from the tip to the substrate is needed. The dependence of the transferred ink volume on the dwell time of the tip on the substrate was investigated by topography measurements with an atomic force microscope (AFM) that is characterized by an ultra-large scan range of 800 × 800 μm2. For this purpose arrays of dots of the phospholipid1,2-dioleoyl-sn-glycero-3-phosphocholine were written onto planar glass substrates and the resulting pattern was imaged by large scan area AFM. Two writing regimes were identified, characterized of either a steady decline or a constant ink volume transfer per dot feature. For the steady state ink transfer, a linear relationship between the dwell time and the dot volume was determined, which is characterized by a flow rate of about 16 femtoliters per second. A dependence of the ink transport from the length of pauses before and in between writing the structures was observed and should be taken into account during pattern design when aiming at best writing homogeneity. The ultra-large scan range of the utilized AFM allowed for a simultaneous study of the entire preparation area of almost 1 mm2, yielding good statistic results.

  1. Reirradiation of Large-Volume Recurrent Glioma With Pulsed Reduced-Dose-Rate Radiotherapy

    International Nuclear Information System (INIS)

    Adkison, Jarrod B.; Tome, Wolfgang; Seo, Songwon; Richards, Gregory M.; Robins, H. Ian; Rassmussen, Karl; Welsh, James S.; Mahler, Peter A.; Howard, Steven P.

    2011-01-01

    Purpose: Pulsed reduced-dose-rate radiotherapy (PRDR) is a reirradiation technique that reduces the effective dose rate and increases the treatment time, allowing sublethal damage repair during irradiation. Patients and Methods: A total of 103 patients with recurrent glioma underwent reirradiation using PRDR (86 considered to have Grade 4 at PRDR). PRDR was delivered using a series of 0.2-Gy pulses at 3-min intervals, creating an apparent dose rate of 0.0667 Gy/min to a median dose of 50 Gy (range, 20-60) delivered in 1.8-2.0-Gy fractions. The mean treatment volume was 403.5 ± 189.4 cm 3 according to T 2 -weighted magnetic resonance imaging and a 2-cm margin. Results: For the initial or upgraded Grade 4 cohort (n = 86), the median interval from the first irradiation to PRDR was 14 months. Patients undergoing PRDR within 14 months of the first irradiation (n = 43) had a median survival of 21 weeks. Those treated ≥14 months after radiotherapy had a median survival of 28 weeks (n = 43; p = 0.004 and HR = 1.82 with a 95% CI ranging from 1.25 to 3.10). These data compared favorably to historical data sets, because only 16% of the patients were treated at first relapse (with 46% treated at the second relapse, 32% at the third or fourth relapse, and 4% at the fourth or fifth relapse). The median survival since diagnosis and retreatment was 6.3 years and 11.4 months for low-grade, 4.1 years and 5.6 months for Grade 3, and 1.6 years and 5.1 months for Grade 4 tumors, respectively, according to the initial histologic findings. Multivariate analysis revealed age at the initial diagnosis, initial low-grade disease, and Karnofsky performance score of ≥80 to be significant predictors of survival after initiation of PRDR. Conclusion: PRDR allowed for safe retreatment of larger volumes to high doses with palliative benefit.

  2. Large Deployable Reflector (LDR) system concept and technology definition study. Volume 1: Executive summary, analyses and trades, and system concepts

    Science.gov (United States)

    Agnew, Donald L.; Jones, Peter A.

    1989-01-01

    A study was conducted to define reasonable and representative large deployable reflector (LDR) system concepts for the purpose of defining a technology development program aimed at providing the requisite technological capability necessary to start LDR development by the end of 1991. This volume includes the executive summary for the total study, a report of thirteen system analysis and trades tasks (optical configuration, aperture size, reflector material, segmented mirror, optical subsystem, thermal, pointing and control, transportation to orbit, structures, contamination control, orbital parameters, orbital environment, and spacecraft functions), and descriptions of three selected LDR system concepts. Supporting information is contained in appendices.

  3. Implication on the core collapse supernova rate from 21 years of data of the Large Volume Detector

    CERN Document Server

    Agafonova, N Y; Antonioli, P; Ashikhmin, V V; Badino, G.; Bari, G; Bertoni, R; Bressan, E; Bruno, G; Dadykin, V L; Dobrynina, E A; Enikeev, R I; Fulgione, W; Galeotti, P; Garbini, M; Ghia, P L; Giusti, P; Gomez, F; Kemp, E; Malgin, A S; Molinario, A; Persiani, R; Pless, I A; Porta, A; Ryasny, V G; Ryazhskaya, O G; Saavedra, O; Sartorelli, G; Shakiryanova, I R; Selvi, M; Trinchero, G C; Vigorito, C; Yakushev, V F; Zichichi, A

    2015-01-01

    The Large Volume Detector (LVD) has been continuously taking data since 1992 at the INFN Gran Sasso National Laboratory. LVD is sensitive to neutrino bursts from gravitational stellar collapses with full detection probability over the Galaxy. We have searched for neutrino bursts in LVD data taken in 7335 days of operation. No evidence of neutrino signals has been found between June 1992 and December 2013. The 90% C.L. upper limit on the rate of core-collapse and failed supernova explosions out to distances of 25 kpc is found to be 0.114/y.

  4. Extraterrestrial processing and manufacturing of large space systems. Volume 3: Executive summary

    Science.gov (United States)

    Miller, R. H.; Smith, D. B. S.

    1979-01-01

    Facilities and equipment are defined for refining processes to commercial grade of lunar material that is delivered to a 'space manufacturing facility' in beneficiated, primary processed quality. The manufacturing facilities and the equipment for producing elements of large space systems from these materials and providing programmatic assessments of the concepts are also defined. In-space production processes of solar cells (by vapor deposition) and arrays, structures and joints, conduits, waveguides, RF equipment radiators, wire cables, converters, and others are described.

  5. Extraterrestrial processing and manufacturing of large space systems, volume 1, chapters 1-6

    Science.gov (United States)

    Miller, R. H.; Smith, D. B. S.

    1979-01-01

    Space program scenarios for production of large space structures from lunar materials are defined. The concept of the space manufacturing facility (SMF) is presented. The manufacturing processes and equipment for the SMF are defined and the conceptual layouts are described for the production of solar cells and arrays, structures and joints, conduits, waveguides, RF equipment radiators, wire cables, and converters. A 'reference' SMF was designed and its operation requirements are described.

  6. Immunoglobulin G levels during collection of large volume plasma for fractionation.

    Science.gov (United States)

    Burkhardt, Thomas; Rothe, Remo; Moog, Rainer

    2017-06-01

    There is a need of comprehensive work dealing with the quality of plasma for fractionation with respect to the IgG content as today most plasma derivates are used to treat patients with immunodeficiencies and autoimmune disorders. Therefore, a prospective study was carried out to analyse IgG levels before plasmapheresis and every 200ml collected plasma. Fifty-four experienced plasmapheresis donors were recruited for subsequent 850ml plasmapheresis using the Aurora Plasmapheresis System. Donorś peripheral blood counts were analysed before and after plasmapheresis using an electronic counter. Total protein, IgG and citrate were measured turbidometrically before, during and after apheresis as well as in the plasma product. Furthermore, platelets, red and white blood cells were analysed as parameters of product quality. An average of 2751±247ml blood was processed in 47±6min. The collected plasma volume was 850±1mL and citrate consumption was 177±15mL. A continuous drop of donors' IgG level was observed during plasmapheresis. The drop was 13% of the IgG baseline value at 800mL collected plasma. Total protein, IgG and cell counts of the plasma product met current guidelines of plasma for fractionation. Donors' IgG levels during apheresis showed a steady decrease without compromising the quality of plasma product. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. Measured and simulated performance of Compton-suppressed TIGRESS HPGe clover detectors

    Science.gov (United States)

    Schumaker, M. A.; Hackman, G.; Pearson, C. J.; Svensson, C. E.; Andreoiu, C.; Andreyev, A.; Austin, R. A. E.; Ball, G. C.; Bandyopadhyay, D.; Boston, A. J.; Chakrawarthy, R. S.; Churchman, R.; Drake, T. E.; Finlay, P.; Garrett, P. E.; Grinyer, G. F.; Hyland, B.; Jones, B.; Maharaj, R.; Morton, A. C.; Phillips, A. A.; Sarazin, F.; Scraggs, H. C.; Smith, M. B.; Valiente-Dobón, J. J.; Waddington, J. C.; Watters, L. M.

    2007-01-01

    Tests of the performance of a 32-fold segmented HPGe clover detector coupled to a 20-fold segmented Compton-suppression shield, which form a prototype element of the TRIUMF-ISAC Gamma-Ray Escape-Suppressed Spectrometer (TIGRESS), have been made. Peak-to-total ratios and relative efficiencies have been measured for a variety of γ-ray energies. These measurements were used to validate a GEANT4 simulation of the TIGRESS detectors, which was then used to create a simulation of the full 12-detector array. Predictions of the expected performance of TIGRESS are presented. These predictions indicate that TIGRESS will be capable, for single 1 MeV γ rays, of absolute detection efficiencies of 17% and 9.4%, and peak-to-total ratios of 54% and 61% for the "high-efficiency" and "optimized peak-to-total" configurations of the array, respectively.

  8. Development of CANDLES low background HPGe detector and half-life measurement of 180Tam

    Science.gov (United States)

    Chan, W. M.; Kishimoto, T.; Umehara, S.; Matsuoka, K.; Suzuki, K.; Yoshida, S.; Nakajima, K.; Iida, T.; Fushimi, K.; Nomachi, M.; Ogawa, I.; Tamagawa, Y.; Hazama, R.; Takemoto, Y.; Nakatani, N.; Takihira, Y.; Tozawa, M.; Kakubata, H.; Trang, V. T. T.; Ohata, T.; Tetsuno, K.; Maeda, T.; Khai, B. T.; Li, X. L.; Batpurev, T.

    2018-01-01

    A low background HPGe detector system was developed at CANDLES Experimental Hall for multipurpose use. Various low background techniques were employed, including hermatic shield design, radon gas suppression, and background reduction analysis. A new pulse shape discrimination (PSD) method was specially created for coaxial Ge detector. Using this PSD method, microphonics noise and background event at low energy region less than 200 keV can be rejected effectively. Monte Carlo simulation by GEANT4 was performed to acquire the detection efficiency and study the interaction of gamma-rays with detector system. For rare decay measurement, the detector was utilized to detect the nature's most stable isomer tantalum-180m (180Tam) decay. Two phases of tantalum physics run were completed with total livetime of 358.2 days, which Phase II has upgraded shield configuration. The world most stringent half-life limit of 180Tam has been successfully achieved.

  9. True coincidence summing corrections for an extended energy range HPGe detector

    Energy Technology Data Exchange (ETDEWEB)

    Venegas-Argumedo, Y. [Centro de Investigación en Materiales Avanzados (CIMAV), Miguel de Cervantes 120, Chihuahua, Chih 31109 (Mexico); M.S. Student at CIMAV (Mexico); Montero-Cabrera, M. E., E-mail: elena.montero@cimav.edu.mx [Centro de Investigación en Materiales Avanzados (CIMAV), Miguel de Cervantes 120, Chihuahua, Chih 31109 (Mexico)

    2015-07-23

    True coincidence summing (TCS) effect for natural radioactive families of U-238 and Th-232 represents a problem when an environmental sample with a close source-detector geometry measurement is performed. By using a certified multi-nuclide standard source to calibrate an energy extended range (XtRa) HPGe detector, it is possible to obtain an intensity spectrum slightly affected by the TCS effect with energies from 46 to 1836 keV. In this work, the equations and some other considerations required to calculate the TCS correction factor for isotopes of natural radioactive chains are described. It is projected a validation of the calibration, performed with the IAEA-CU-2006-03 samples (soil and water)

  10. GRABGAM: A Gamma Analysis Code for Ultra-Low-Level HPGe SPECTRA

    Energy Technology Data Exchange (ETDEWEB)

    Winn, W.G.

    1999-07-28

    The GRABGAM code has been developed for analysis of ultra-low-level HPGe gamma spectra. The code employs three different size filters for the peak search, where the largest filter provides best sensitivity for identifying low-level peaks and the smallest filter has the best resolution for distinguishing peaks within a multiplet. GRABGAM basically generates an integral probability F-function for each singlet or multiplet peak analysis, bypassing the usual peak fitting analysis for a differential f-function probability model. Because F is defined by the peak data, statistical limitations for peak fitting are avoided; however, the F-function does provide generic values for peak centroid, full width at half maximum, and tail that are consistent with a Gaussian formalism. GRABGAM has successfully analyzed over 10,000 customer samples, and it interfaces with a variety of supplementary codes for deriving detector efficiencies, backgrounds, and quality checks.

  11. Measurement of radiation shielding properties of polymer composites by using HPGe detector

    International Nuclear Information System (INIS)

    Gupta, Anil; Pillay, H.C.M.; Kale, P.K.; Datta, D.; Suman, S.K.; Gover, V.

    2014-01-01

    Lead is the most common radiation shield and its composite with polymers can be used as flexible radiation shields for different applications. However, lead is very hazardous and has been found to be associated with neurological disorders, kidney failure and hematotoxicity. Lead free radiation shield material has been developed by synthesizing radiation cross linked PDMS/Bi 2 O 3 polymer composites. In order to have a lead free radiation shield the relevant shielding properties such as linear attenuation, half value thickness (HVT) and tenth value thickness (TVT) have been measured by using HPGe detector. The present study describes the methodology of measurement of the shielding properties of the lead free shield material. In the measurement gamma energies such as 59.537 keV ( 241 Am), 122.061 keV and 136.474 keV ( 57 Co) are taken into consideration

  12. Determination of radionuclides for river sediment CRM with HPGe gamma-ray spectrometer

    International Nuclear Information System (INIS)

    Tan Jinbo; Hao Runlong; Tang Zhenxin

    1994-01-01

    The authors described the method and results for determination of seven radionuclides: 238 U, 235 U, 226 Ra, 232 Th, 40 K, 60 Co and 137 Cs in the river sediment Certified Reference Material (CRM) using a HPGe gamma-ray spectrometer. The accuracy and reliability of measurement results were improved through varieties of techniques, which include: precise calibration of the gamma-ray spectrometer, coincidence summing correction and interference peak correction, two kinds of peak analysis methods (TPA and function fit), and utilization of as many as possible characteristic gamma-rays. Present measurement results for the seven radionuclides were in agreement with the verification results of the CRM with 1 σ or 2σ uncertainty, and its relative deviation were in the range of +1.0%--6.5%

  13. Simulation for photon detection in spectrometric system of high purity (HPGe) using MCNPX code

    International Nuclear Information System (INIS)

    Correa, Guilherme Jorge de Souza

    2013-01-01

    The Brazilian National Commission of Nuclear Energy defines parameters for classification and management of radioactive waste in accordance with the activity of materials. The efficiency of a detection system is crucial to determine the real activity of a radioactive source. When it's possible, the system's calibration should be performed using a standard source. Unfortunately, there are only a few cases that it can be done this way, considering the difficulty of obtaining appropriate standard sources for each type of measurement. So, computer simulations can be performed to assist in calculating of the efficiency of the system and, consequently, also auxiliary the classification of radioactive waste. This study aims to model a high purity germanium (HPGe) detector with MCNPX code, approaching the spectral values computationally obtained of the values experimentally obtained for the photopeak of 137 Cs. The approach will be made through changes in outer dead layer of the germanium crystal modeled. (author)

  14. Calibration efficiency of HPGe detector in the 50-1800 KeV energy range

    International Nuclear Information System (INIS)

    Venturini, Luzia

    1996-01-01

    This paper describes the efficiency of an HPGe detector in the 50 - 1800 keV energy range, for two geometries for water measurements: Marinelli breaker (850 ml) and a polyethylene flask (100 ml). The experimental data were corrected for the summing effect and fitted to a continuous, differentiable and energy dependent function given by 1n(ε)=b 0 +b 1 .1n(E/E 0 )+ β.1n(E/E 0 ) 2 , where β = b 2 if E>E 0 and β =a 2 if E ≤E 0 ; ε = the full absorption peak efficiency; E is the gamma-ray energy and {b 0 , b 1 , b 2 , a 2 , E 0 } is the parameter set to be fitted. (author)

  15. Comparison measure of natural radioactivity in environment specimen using HPGe and NaI(Tl) γ-ray spectrometer

    International Nuclear Information System (INIS)

    Zhou Chunlin; Han Feng; Li Tiantuo; Ma Wenyan; Di Yuming; Guo Huiping; Wu Yuelei

    2000-01-01

    The author reports the comparison results on natural radioactive nuclide contents of soil specimen from an uranium diggings with HPGe and NaI(Tl) γ-ray spectrometer. Relative method and athwart matrix method are used to analyze natural radioactive nuclide contents in samples of soil. The results are compared and are proven to be in accordance with each other

  16. Use of planar HPGe detector as a part of X-ray fluorescent spectrometer for educational purposes

    International Nuclear Information System (INIS)

    Verenchikova, M.S.; Kalinin, V.N.; Mikhajlov, V.A.

    2011-01-01

    This work shows the possibility of use of the nondedicated gamma and X-ray detection head on the basis of planar HPGe detector with a big sensitive area equal to 2000 mm''2 as a part of X-ray fluorescent spectrometer during students' practicum.

  17. Optimization of statistical methods for HpGe gamma-ray spectrometer used in wide count rate ranges

    Energy Technology Data Exchange (ETDEWEB)

    Gervino, G., E-mail: gervino@to.infn.it [UNITO - Università di Torino, Dipartimento di Fisica, Turin (Italy); INFN - Istituto Nazionale di Fisica Nucleare, Sez. Torino, Turin (Italy); Mana, G. [INRIM - Istituto Nazionale di Ricerca Metrologica, Turin (Italy); Palmisano, C. [UNITO - Università di Torino, Dipartimento di Fisica, Turin (Italy); INRIM - Istituto Nazionale di Ricerca Metrologica, Turin (Italy)

    2016-07-11

    The need to perform γ-ray measurements with HpGe detectors is a common technique in many fields such as nuclear physics, radiochemistry, nuclear medicine and neutron activation analysis. The use of HpGe detectors is chosen in situations where isotope identification is needed because of their excellent resolution. Our challenge is to obtain the “best” spectroscopy data possible in every measurement situation. “Best” is a combination of statistical (number of counts) and spectral quality (peak, width and position) over a wide range of counting rates. In this framework, we applied Bayesian methods and the Ellipsoidal Nested Sampling (a multidimensional integration technique) to study the most likely distribution for the shape of HpGe spectra. In treating these experiments, the prior information suggests to model the likelihood function with a product of Poisson distributions. We present the efforts that have been done in order to optimize the statistical methods to HpGe detector outputs with the aim to evaluate to a better order of precision the detector efficiency, the absolute measured activity and the spectra background. Reaching a more precise knowledge of statistical and systematic uncertainties for the measured physical observables is the final goal of this research project.

  18. Qualitative and quantitative validation of the SINBAD code on complex HPGe gamma-ray spectra

    Energy Technology Data Exchange (ETDEWEB)

    Rohee, E.; Coulon, R.; Normand, S.; Carrel, F. [CEA, LIST, Laboratoire Capteurs et Architectures electroniques, F-91191 Gif-sur-Yvette, (France); Dautremer, T.; Barat, E.; Montagu, T. [CEA, LIST, Laboratoire Modelisation, Simulation et Systemes, F-91191 Gif-sur-Yvette, (France); Jammes, C. [CEA/DEN/SPEx/LDCI, Centre de Cadarache, F-13109 Saint-Paul-lez-Durance, (France)

    2015-07-01

    Radionuclides identification and quantification is a serious concern for many applications as safety or security of nuclear power plant or fuel cycle facility, CBRN risk identification, environmental radioprotection and waste measurements. High resolution gamma-ray spectrometry based on HPGe detectors is a performing solution for all these topics. During last decades, a great number of software has been developed to improve gamma spectra analysis. However, some difficulties remain in the analysis when photoelectric peaks are folded together with a high ratio between theirs amplitudes, when the Compton background is much larger compared to the signal of a single peak and when spectra are composed of a great number of peaks. This study deals with the comparison between conventional methods in radionuclides identification and quantification and the code called SINBAD ('Spectrometrie par Inference Non parametrique Bayesienne Deconvolutive'). For many years, SINBAD has been developed by CEA LIST for unfolding complex spectra from HPGe detectors. Contrary to conventional methods using fitting procedures, SINBAD uses a probabilistic approach with Bayesian inference to describe spectrum data. This conventional fitting method founded for example in Genie 2000 is compared with the nonparametric SINBAD approach regarding some key figures of merit as the peak centroid evaluation (identification) and peak surface evaluation (quantification). Unfriendly cases are studied for nuclides detection with closed gamma-rays energies and high photoelectric peak intensity differences. Tests are performed with spectra from the International Atomic Energy Agency (IAEA) for gamma spectra analysis software benchmark and with spectra acquired at the laboratory. Results show that SINBAD and Genie 2000 performances are quite similar with sometimes best results for SINBAD with the important difference that to achieve same performances the nonparametric method is user-friendly compared

  19. Measurements of radionuclide in Par Pond sediments with an underwater HPGe detector

    International Nuclear Information System (INIS)

    Winn, W.G.

    1993-01-01

    Savannah River Site (SRS) effluent gamma emitting radionuclides in Par Pond sediment were examined in situ with an underwater HPGe detector prior to and following a 19 ft drawdown of the pond in 1991 to address dam repairs. These measurements provide a map of the 137 Cs concentrations of the pond sediment, indicating that 9.4 ± 1.5 Ci is exposed by the drawdown and that 46.6 ± 7.2 Ci is the entire pond inventory. The highest individual 137 Cs concentration was 25 μCi/m 2 for the exposed sediment and 50 μCi/m 2 for the entire pond. The results are consistent with parallel studies conducted by SREL, as well as historical data. Aside from 137 Cs, the only other SRS-produced isotope observed was 60 Co, with activity of only about 1% of that for 137 Cs. This observation was also confirmed in grab samples of pond sediment and vegetation, which were returned to the laboratory for ultra-low-level gamma spectrometry analysis. A special effort was required to calibrate the underwater HPGe detector, where both measurements and calculational models were used. The effects of sediment depth profiles for density and 137 Cs concentration were addressed in the calibration. Calibration factors for sediment surface concentrations (μCi/m 2 /cpm) and sediment mass concentrations (pCi/kg/cpm) were obtained. In general, the μCi/m 2 /cpm factor is recommended, as the pCi/kg/cpm factor depends on the depth location of the sediment of interest. However, a pCi/kg/cpm factor, which is dependent on the depth within the sediment is presented to address dose calculations that require it

  20. Hierarchical storage of large volume of multidector CT data using distributed servers

    Science.gov (United States)

    Ratib, Osman; Rosset, Antoine; Heuberger, Joris; Bandon, David

    2006-03-01

    Multidector scanners and hybrid multimodality scanners have the ability to generate large number of high-resolution images resulting in very large data sets. In most cases, these datasets are generated for the sole purpose of generating secondary processed images and 3D rendered images as well as oblique and curved multiplanar reformatted images. It is therefore not essential to archive the original images after they have been processed. We have developed an architecture of distributed archive servers for temporary storage of large image datasets for 3D rendering and image processing without the need for long term storage in PACS archive. With the relatively low cost of storage devices it is possible to configure these servers to hold several months or even years of data, long enough for allowing subsequent re-processing if required by specific clinical situations. We tested the latest generation of RAID servers provided by Apple computers with a capacity of 5 TBytes. We implemented a peer-to-peer data access software based on our Open-Source image management software called OsiriX, allowing remote workstations to directly access DICOM image files located on the server through a new technology called "bonjour". This architecture offers a seamless integration of multiple servers and workstations without the need for central database or complex workflow management tools. It allows efficient access to image data from multiple workstation for image analysis and visualization without the need for image data transfer. It provides a convenient alternative to centralized PACS architecture while avoiding complex and time-consuming data transfer and storage.

  1. Onco plastic volume replacement with latissimus dorsi myocutaneous flap in patients with large ptotic breasts. Is it feasible?

    International Nuclear Information System (INIS)

    El-Marakby, H.H.; Kotb, M.H.

    2011-01-01

    Onco plastic breast conservative surgery has evolved as a safe alternative to the standard mastectomy in the treatment of early breast cancer. The procedure involves tumour resection with an adequate safety margin and either breast reshaping with volume displacement procedures (large or pt otic breasts) or volume replacement with latissimus dorsi myocutaneous flap (LDF) (small to medium sized non-ptotic breasts). A contra lateral mastopexy procedure is usually necessary with the volume displacement Onco plastic surgery, a procedure that is often rejected by a significant number of patients. This limits the choice of the reconstruction of breast defects in such patients to autologous tissues i.e. LDF. Aim: Aim is to evaluate the feasibility of volume replacement onco plastic breast conservative surgery with lemmatise dorsi myocutaneous flaps for patients with large ptotic breasts. This involves testing the oncologic safety in terms of adequate safety margin, the complications rate and the final cosmetic outcome. The loco regional recurrence rate will be recorded and compared with oncoplastic volume displacement for similar sized breast defects. Patients and methods: A group of 50 female patients with early breast cancers (T2) who presented to the department of surgery at the National Cancer Institute, Cairo, Egypt in the period between carried out in all patient groups and was used to annually follow up the patients. All patients were detected with T2 NO breast cancer by both clinical and radiological examinations. All patients underwent partial mastectomy was and reconstruction with LDFs. Results: The average age at presentation was 46.5 ± 9 years and the range was 26-65 years. Most of the patients were subjected to partial mastectomy in 30 patients (60%), excision of a single quadrant from the four major quadrants was carried out in 15 patients (30%) where skin sparing wide local excision was carried out in only five patients (10%). The safety margin ranged from

  2. No evidence of a threshold in traffic volume affecting road-kill mortality at a large spatio-temporal scale

    Energy Technology Data Exchange (ETDEWEB)

    Grilo, Clara, E-mail: clarabentesgrilo@gmail.com [Departamento de Biología de la Conservación, Estación Biológica de Doñana (EBD-CSIC), Calle Américo Vespucio s/n, E-41092 Sevilla (Spain); Centro Brasileiro de Estudos em Ecologia de Estradas, Departamento de Biologia, Universidade Federal de Lavras, Campus Universitário, 37200-000 Lavras, Minas Gerais (Brazil); Ferreira, Flavio Zanchetta; Revilla, Eloy [Departamento de Biología de la Conservación, Estación Biológica de Doñana (EBD-CSIC), Calle Américo Vespucio s/n, E-41092 Sevilla (Spain)

    2015-11-15

    Previous studies have found that the relationship between wildlife road mortality and traffic volume follows a threshold effect on low traffic volume roads. We aimed at evaluating the response of several species to increasing traffic intensity on highways over a large geographic area and temporal period. We used data of four terrestrial vertebrate species with different biological and ecological features known by their high road-kill rates: the barn owl (Tyto alba), hedgehog (Erinaceus europaeus), red fox (Vulpes vulpes) and European rabbit (Oryctolagus cuniculus). Additionally, we checked whether road-kill likelihood varies when traffic patterns depart from the average. We used annual average daily traffic (AADT) and road-kill records observed along 1000 km of highways in Portugal over seven consecutive years (2003–2009). We fitted candidate models using Generalized Linear Models with a binomial distribution through a sample unit of 1 km segments to describe the effect of traffic on the probability of finding at least one victim in each segment during the study. We also assigned for each road-kill record the traffic of that day and the AADT on that year to test for differences using Paired Student's t-test. Mortality risk declined significantly with traffic volume but varied among species: the probability of finding road-killed red foxes and rabbits occurs up to moderate traffic volumes (< 20,000 AADT) whereas barn owls and hedgehogs occurred up to higher traffic volumes (40,000 AADT). Perception of risk may explain differences in responses towards high traffic highway segments. Road-kill rates did not vary significantly when traffic intensity departed from the average. In summary, we did not find evidence of traffic thresholds for the analysed species and traffic intensities. We suggest mitigation measures to reduce mortality be applied in particular on low traffic roads (< 5000 AADT) while additional measures to reduce barrier effects should take into

  3. No evidence of a threshold in traffic volume affecting road-kill mortality at a large spatio-temporal scale

    International Nuclear Information System (INIS)

    Grilo, Clara; Ferreira, Flavio Zanchetta; Revilla, Eloy

    2015-01-01

    Previous studies have found that the relationship between wildlife road mortality and traffic volume follows a threshold effect on low traffic volume roads. We aimed at evaluating the response of several species to increasing traffic intensity on highways over a large geographic area and temporal period. We used data of four terrestrial vertebrate species with different biological and ecological features known by their high road-kill rates: the barn owl (Tyto alba), hedgehog (Erinaceus europaeus), red fox (Vulpes vulpes) and European rabbit (Oryctolagus cuniculus). Additionally, we checked whether road-kill likelihood varies when traffic patterns depart from the average. We used annual average daily traffic (AADT) and road-kill records observed along 1000 km of highways in Portugal over seven consecutive years (2003–2009). We fitted candidate models using Generalized Linear Models with a binomial distribution through a sample unit of 1 km segments to describe the effect of traffic on the probability of finding at least one victim in each segment during the study. We also assigned for each road-kill record the traffic of that day and the AADT on that year to test for differences using Paired Student's t-test. Mortality risk declined significantly with traffic volume but varied among species: the probability of finding road-killed red foxes and rabbits occurs up to moderate traffic volumes (< 20,000 AADT) whereas barn owls and hedgehogs occurred up to higher traffic volumes (40,000 AADT). Perception of risk may explain differences in responses towards high traffic highway segments. Road-kill rates did not vary significantly when traffic intensity departed from the average. In summary, we did not find evidence of traffic thresholds for the analysed species and traffic intensities. We suggest mitigation measures to reduce mortality be applied in particular on low traffic roads (< 5000 AADT) while additional measures to reduce barrier effects should take into

  4. Paul Scherrer Institute Scientific and Technical Report 2000. Volume VI: Large Research Facilities

    International Nuclear Information System (INIS)

    Foroughi, Fereydoun; Bercher, Renate; Buechli, Carmen; Zumkeller, Lotty

    2001-01-01

    The PSI Department Large Research Facilities (GFA) joins the efforts to provide an excellent research environment to Swiss and foreign research groups on the experimental facilities driven by our high intensity proton accelerator complex. Its divisions care for the running, maintenance and enhancement of the accelerator complex, the primary proton beamlines, the targets and the secondary beams as well as the neutron spallation source SINQ. The division for technical support and coordination provides for technical support to the research facility complementary to the basic logistic available from the department for logistics and marketing. Besides running the facilities, the staff of the department is also involved in theoretical and experimental research projects. Some of them address basic scientific questions mainly concerning the properties of micro- or nanostructured materials: experiments as well as large scale computer simulations of molecular dynamics were performed to investigate nonclassical materials properties. Others are related to improvements or extensions of the capabilities of our facilities. We also report on intriguing results from applications of the neutron capture radiography, the prompt gamma activation method and the isotope production facility at SINQ

  5. Paul Scherrer Institute Scientific and Technical Report 2000. Volume VI: Large Research Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Foroughi, Fereydoun; Bercher, Renate; Buechli, Carmen; Zumkeller, Lotty [eds.

    2001-07-01

    The PSI Department Large Research Facilities (GFA) joins the efforts to provide an excellent research environment to Swiss and foreign research groups on the experimental facilities driven by our high intensity proton accelerator complex. Its divisions care for the running, maintenance and enhancement of the accelerator complex, the primary proton beamlines, the targets and the secondary beams as well as the neutron spallation source SINQ. The division for technical support and coordination provides for technical support to the research facility complementary to the basic logistic available from the department for logistics and marketing. Besides running the facilities, the staff of the department is also involved in theoretical and experimental research projects. Some of them address basic scientific questions mainly concerning the properties of micro- or nanostructured materials: experiments as well as large scale computer simulations of molecular dynamics were performed to investigate nonclassical materials properties. Others are related to improvements or extensions of the capabilities of our facilities. We also report on intriguing results from applications of the neutron capture radiography, the prompt gamma activation method and the isotope production facility at SINQ.

  6. Computational characterization of HPGe detectors usable for a wide variety of source geometries by using Monte Carlo simulation and a multi-objective evolutionary algorithm

    Science.gov (United States)

    Guerra, J. G.; Rubiano, J. G.; Winter, G.; Guerra, A. G.; Alonso, H.; Arnedo, M. A.; Tejera, A.; Martel, P.; Bolivar, J. P.

    2017-06-01

    In this work, we have developed a computational methodology for characterizing HPGe detectors by implementing in parallel a multi-objective evolutionary algorithm, together with a Monte Carlo simulation code. The evolutionary algorithm is used for searching the geometrical parameters of a model of detector by minimizing the differences between the efficiencies calculated by Monte Carlo simulation and two reference sets of Full Energy Peak Efficiencies (FEPEs) corresponding to two given sample geometries, a beaker of small diameter laid over the detector window and a beaker of large capacity which wrap the detector. This methodology is a generalization of a previously published work, which was limited to beakers placed over the window of the detector with a diameter equal or smaller than the crystal diameter, so that the crystal mount cap (which surround the lateral surface of the crystal), was not considered in the detector model. The generalization has been accomplished not only by including such a mount cap in the model, but also using multi-objective optimization instead of mono-objective, with the aim of building a model sufficiently accurate for a wider variety of beakers commonly used for the measurement of environmental samples by gamma spectrometry, like for instance, Marinellis, Petris, or any other beaker with a diameter larger than the crystal diameter, for which part of the detected radiation have to pass through the mount cap. The proposed methodology has been applied to an HPGe XtRa detector, providing a model of detector which has been successfully verificated for different source-detector geometries and materials and experimentally validated using CRMs.

  7. Radio-chemical dosage of {sup 90}Sr in large volumes of drinking water; Dosage radiochimique du {sup 90}Sr sur des volumes importants d'eaux potables

    Energy Technology Data Exchange (ETDEWEB)

    Jeanmaire, L; Patti, F; Bullier, D [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1965-07-01

    I. Principle of the method: 1. Fixing on a resin of all the cations present in the water. 2. Elution using 5 N nitric acid and precipitation of strontium as the carbonate. 3. Concentration of the strontium using the fuming nitric acid method. 4. Purification of the strontium on a resin by selective elution with ammonium citrate. 5. The strontium-90 is measured by separation at the {sup 90}Y equilibrium in the form of the oxalate which is then counted. II. Advantages of the method The concentration of the radio-activity starting from large volumes (100 l) is generally tedious but this method which makes use of a fixation on a cationic resin makes it very simple. The rest of the method consists of a series of simple chemical operations using ion-exchange on resins and coprecipitation. Finally, it is possible to dose stable strontium. (authors) [French] I. Principe du dosage 1. Fixation sur resine de tous les cations presents dans l'eau, 2. Elution par l'acide nitrique 5 N et precipitation du strontium sous forme de carbonate. 3. Concentration du strontium par la methode a l'acide nitrique fumant. 4. Purification du strontium sur resine par elution selective au citrate d'ammonium. 5. Le strontium-90 est dose par separation a l'equilibre du {sup 90}Y sous forme d'oxalate qui est compte. II. Interet de la methode La concentration de la radioactivite a partir de volumes importants (100 l) est generalement fastidieuse, la technique proposee rend cette phase tres simple en utilisant une fixation sur resine cationique. Le reste de la technique est une suite d'operations chimiques simples a realiser, faisant appel a l'echange d'ions sur resine et a la coprecipitation. Enfin, il est possible de realiser le dosage du strontium stable. (auteurs)

  8. Material properties of large-volume cadmium zinc telluride crystals and their relationship to nuclear detector performance

    Energy Technology Data Exchange (ETDEWEB)

    James, R.B.; Lund, J. [Sandia National Labs., Livermore, CA (United States); Yoon, H. [Sandia National Labs., Livermore, CA (United States)]|[Univ. of California, Los Angeles, CA (United States)] [and others

    1997-09-01

    The material showing the greatest promise today for production of large-volume gamma-ray spectrometers operable at room temperature is cadmium zinc telluride (CZT). Unfortunately, because of deficiencies in the quality of the present material, high-resolution CZT spectrometers have thus far been limited to relatively small dimensions, which makes them inefficient at detecting high photon energies and ineffective for weak radiation signals except in near proximity. To exploit CZT fully, it will be necessary to make substantial improvements in the material quality. Improving the material involves advances in the purity, crystallinity, and control of the electrical compensation mechanism. Sandia National Laboratories, California, in close collaboration with US industry and academia, has initiated efforts to develop a detailed understanding of the underlying material problems limiting the performance of large volume gamma-ray spectrometers and to overcome them through appropriate corrections therein. A variety of analytical and numerical techniques are employed to quantify impurities, compositional and stoichiometric variations, crystallinity, strain, bulk and surface defect states, carrier mobilities and lifetimes, electric field distributions, and contact chemistry. Data from these measurements are correlated with spatial maps of the gamma-ray and alpha particle spectroscopic response to determine improvements in the material purification, crystal growth, detector fabrication, and surface passivation procedures. The results of several analytical techniques will be discussed. The intended accomplishment of this work is to develop a low-cost, high-efficiency CZT spectrometer with an active volume of 5 cm{sup 3} and energy resolution of 1--2% (at 662 keV), which would give the US a new field capability for screening radioactive substances.

  9. SyPRID sampler: A large-volume, high-resolution, autonomous, deep-ocean precision plankton sampling system

    Science.gov (United States)

    Billings, Andrew; Kaiser, Carl; Young, Craig M.; Hiebert, Laurel S.; Cole, Eli; Wagner, Jamie K. S.; Van Dover, Cindy Lee

    2017-03-01

    The current standard for large-volume (thousands of cubic meters) zooplankton sampling in the deep sea is the MOCNESS, a system of multiple opening-closing nets, typically lowered to within 50 m of the seabed and towed obliquely to the surface to obtain low-spatial-resolution samples that integrate across 10 s of meters of water depth. The SyPRID (Sentry Precision Robotic Impeller Driven) sampler is an innovative, deep-rated (6000 m) plankton sampler that partners with the Sentry Autonomous Underwater Vehicle (AUV) to obtain paired, large-volume plankton samples at specified depths and survey lines to within 1.5 m of the seabed and with simultaneous collection of sensor data. SyPRID uses a perforated Ultra-High-Molecular-Weight (UHMW) plastic tube to support a fine mesh net within an outer carbon composite tube (tube-within-a-tube design), with an axial flow pump located aft of the capture filter. The pump facilitates flow through the system and reduces or possibly eliminates the bow wave at the mouth opening. The cod end, a hollow truncated cone, is also made of UHMW plastic and includes a collection volume designed to provide an area where zooplankton can collect, out of the high flow region. SyPRID attaches as a saddle-pack to the Sentry vehicle. Sentry itself is configured with a flight control system that enables autonomous survey paths to low altitudes. In its verification deployment at the Blake Ridge Seep (2160 m) on the US Atlantic Margin, SyPRID was operated for 6 h at an altitude of 5 m. It recovered plankton samples, including delicate living larvae, from the near-bottom stratum that is seldom sampled by a typical MOCNESS tow. The prototype SyPRID and its next generations will enable studies of plankton or other particulate distributions associated with localized physico-chemical strata in the water column or above patchy habitats on the seafloor.

  10. Material properties of large-volume cadmium zinc telluride crystals and their relationship to nuclear detector performance

    International Nuclear Information System (INIS)

    James, R.B.; Lund, J.; Yoon, H.

    1997-01-01

    The material showing the greatest promise today for production of large-volume gamma-ray spectrometers operable at room temperature is cadmium zinc telluride (CZT). Unfortunately, because of deficiencies in the quality of the present material, high-resolution CZT spectrometers have thus far been limited to relatively small dimensions, which makes them inefficient at detecting high photon energies and ineffective for weak radiation signals except in near proximity. To exploit CZT fully, it will be necessary to make substantial improvements in the material quality. Improving the material involves advances in the purity, crystallinity, and control of the electrical compensation mechanism. Sandia National Laboratories, California, in close collaboration with US industry and academia, has initiated efforts to develop a detailed understanding of the underlying material problems limiting the performance of large volume gamma-ray spectrometers and to overcome them through appropriate corrections therein. A variety of analytical and numerical techniques are employed to quantify impurities, compositional and stoichiometric variations, crystallinity, strain, bulk and surface defect states, carrier mobilities and lifetimes, electric field distributions, and contact chemistry. Data from these measurements are correlated with spatial maps of the gamma-ray and alpha particle spectroscopic response to determine improvements in the material purification, crystal growth, detector fabrication, and surface passivation procedures. The results of several analytical techniques will be discussed. The intended accomplishment of this work is to develop a low-cost, high-efficiency CZT spectrometer with an active volume of 5 cm 3 and energy resolution of 1--2% (at 662 keV), which would give the US a new field capability for screening radioactive substances

  11. SU-F-T-538: CyberKnife with MLC for Treatment of Large Volume Tumors: A Feasibility Study

    Energy Technology Data Exchange (ETDEWEB)

    Bichay, T; Mayville, A [Mercy Health, Saint Mary’s, Grand Rapids, MI (United States)

    2016-06-15

    Purpose: CyberKnife is a well-documented modality for SRS and SBRT treatments. Typical tumors are small and 1–5 fractions are usually used. We determined the feasibility of using CyberKnife, with an InCise multileaf collimator option, for larger tumors undergoing standard dose and fractionation. The intent was to understand the limitation of using this modality for other external beam radiation treatments. Methods: Five tumors from different anatomical sites with volumes from 127.8 cc to 1,320.5 cc were contoured and planned on a Multiplan V5.1 workstation. The target average diameter ranged from 7 cm to 13 cm. The dose fractionation was 1.8–2.0 Gy/fraction and 25–45 fractions for total doses of 45–81 Gy. The sites planned were: pancreas, head and neck, prostate, anal, and esophagus. The plans were optimized to meet conventional dose constraints based on various RTOG protocols for conventional fractionation. Results: The Multiplan treatment planning system successfully generated clinically acceptable plans for all sites studied. The resulting dose distributions achieved reasonable target coverage, all greater than 95%, and satisfactory normal tissue sparing. Treatment times ranged from 9 minutes to 38 minutes, the longest being a head and neck plan with dual targets receiving different doses and with multiple adjacent critical structures. Conclusion: CyberKnife, with the InCise multileaf collimation option, can achieve acceptable dose distributions in large volume tumors treated with conventional dose and fractionation. Although treatment times are greater than conventional accelerator time; target coverage and dose to critical structures can be kept within a clinically acceptable range. While time limitations exist, when necessary CyberKnife can provide an alternative to traditional treatment modalities for large volume tumors.

  12. Large volume unresectable locally advanced non-small cell lung cancer: acute toxicity and initial outcome results with rapid arc

    Directory of Open Access Journals (Sweden)

    Fogliata Antonella

    2010-10-01

    Full Text Available Abstract Background To report acute toxicity, initial outcome results and planning therapeutic parameters in radiation treatment of advanced lung cancer (stage III with volumetric modulated arcs using RapidArc (RA. Methods Twenty-four consecutive patients were treated with RA. All showed locally advanced non-small cell lung cancer with stage IIIA-IIIB and with large volumes (GTV:299 ± 175 cm3, PTV:818 ± 206 cm3. Dose prescription was 66Gy in 33 fractions to mean PTV. Delivery was performed with two partial arcs with a 6 MV photon beam. Results From a dosimetric point of view, RA allowed us to respect most planning objectives on target volumes and organs at risk. In particular: for GTV D1% = 105.6 ± 1.7%, D99% = 96.7 ± 1.8%, D5%-D95% = 6.3 ± 1.4%; contra-lateral lung mean dose resulted in 13.7 ± 3.9Gy, for spinal cord D1% = 39.5 ± 4.0Gy, for heart V45Gy = 9.0 ± 7.0Gy, for esophagus D1% = 67.4 ± 2.2Gy. Delivery time was 133 ± 7s. At three months partial remission > 50% was observed in 56% of patients. Acute toxicities at 3 months showed 91% with grade 1 and 9% with grade 2 esophageal toxicity; 18% presented grade 1 and 9% with grade 2 pneumonia; no grade 3 acute toxicity was observed. The short follow-up does not allow assessment of local control and progression free survival. Conclusions RA proved to be a safe and advantageous treatment modality for NSCLC with large volumes. Long term observation of patients is needed to assess outcome and late toxicity.

  13. Potential of electrical gas discharges for pollution control of large gas volumes

    International Nuclear Information System (INIS)

    Kogelschatz, U.

    1997-01-01

    Non-equilibrium gas discharges in many cases offer an innovative approach to the solution cf industrial air pollution problems. Negative corona discharges are used in electrostatic precipitators to collect dust and fly ash particles. Pulsed positive streamer coronas, dielectric-barrier discharges and possibly also flow-stabilised high pressure glow discharges are emerging technologies for the destruction of air pollutants like nitrogen oxides and sulfur dioxide in flue gases and volatile organic compounds (VOCs) in industrial effluents. The different discharge types are discussed with special emphasis on their potential for upscaling. Major applications are expected particularly in the removal of dilute concentrations of air pollutants, in odour control and in the simultaneous removal of different pollutants. Dielectric-barrier discharges exhibit disposal efficiencies similar to those of pulsed positive streamer coronas and require less sophisticated feeding circuits in large-scale industrial applications. (author)

  14. Critical joints in large composite primary aircraft structures. Volume 2: Technology demonstration test report

    Science.gov (United States)

    Bunin, Bruce L.

    1985-01-01

    A program was conducted to develop the technology for critical structural joints in composite wing structure that meets all the design requirements of a 1990 commercial transport aircraft. The results of four large composite multirow bolted joint tests are presented. The tests were conducted to demonstrate the technology for critical joints in highly loaded composite structure and to verify the analytical methods that were developed throughout the program. The test consisted of a wing skin-stringer transition specimen representing a stringer runout and skin splice on the wing lower surface at the side of the fuselage attachment. All tests were static tension tests. The composite material was Toray T-300 fiber with Ciba-Geigy 914 resin in 10 mil tape form. The splice members were metallic, using combinations of aluminum and titanium. Discussions are given of the test article, instrumentation, test setup, test procedures, and test results for each of the four specimens. Some of the analytical predictions are also included.

  15. Critical joints in large composite primary aircraft structures. Volume 1: Technical summary

    Science.gov (United States)

    Bunin, Bruce L.

    1985-01-01

    A program was conducted at Douglas Aircraft Company to develop the technology for critical joints in composite wing structure that meets all the design requirements of a 1990 commercial transport aircraft. In fulfilling this objective, analytical procedures for joint design and analysis were developed during Phase 1 of the program. Tests were conducted at the element level to supply the empirical data required for methods development. Large composite multirow joints were tested to verify the selected design concepts and for correlation with analysis predictions. The Phase 2 program included additional tests to provide joint design and analysis data, and culminated with several technology demonstration tests of a major joint area representative of a commercial transport wing. The technology demonstration program of Phase 2 is discussed. The analysis methodology development, structural test program, and correlation between test results and analytical strength predictions are reviewed.

  16. Periodic long-range transport in a large volume dc glow discharge dusty plasma

    International Nuclear Information System (INIS)

    Thomas, Edward Jr.; Amatucci, William E.; Compton, Christopher; Christy, Brian; Jackson, Jon David

    2003-01-01

    In an earlier paper, the authors reported on observations of a variety of particle transport phenomena observed in DUPLEX--the DUsty PLasma EXperiment at the Naval Research Laboratory [E. Thomas, Jr., W. E. Amatucci, C. Compton, and B. Christy, Phys. Plasmas 9, 3154 (2002)]. DUPLEX is a large, transparent polycarbonate cylinder that is 40 cm in radius and 80 cm in height. dc glow discharge argon plasmas are generated in DUPLEX. In this paper, the authors expand upon one particular feature of particle transport in DUPLEX, the long-range (i.e., greater than 15 cm), periodic (T∼2.5 min) transport of suspended alumina particles through the plasma. A detailed description of this particle motion through the plasma is presented. Finally, a qualitative model describing the phenomena that lead to this transport is also given

  17. Study of function response of a detector HPGe to photons of reaction 19F(p,αγ)16O

    International Nuclear Information System (INIS)

    Tridapalli, D.B.

    2006-01-01

    In the 19 F(p,αγ) 16 O reaction, characteristic gamma-rays with energies: 6.1 MeV; 6.9 MeV and 7.1 keV can be observed. These photons can be used in many important applications such as Proton Induced Gamma-ray Emission (PIGE), gamma radiography and calibration purposes. It has another advantage in calibration procedures, which is the observed photon flux is greater than other reactions studied, 27 Al(p,αγ) 28 Si and 23 Na(p,αγ) 24 Mg. In our laboratory, we are studying the efficiency and response function of HPGe detectors for high energy photons, and for this it is necessary a source with a level scheme with few gamma-ray transitions and known relative yields. The 19 F(p,αγ) 16 O reaction satisfies the first condition but in the literature we found relative yields for thick targets or reaction cross section for thin targets. However, we use targets of intermediate thickness, therefore in this work we measure the relative gamma-ray yields for protons with energies between 1.36 MeV and 1.42 MeV. The experiments were performed at the 1.7 MV Pelletron tandem accelerator of the Laboratorio de Analise de Materiais por Feixes Ionicos (LAMFI) located at Instituto de Fisica da Universidade de Sao Paulo, using a reverse-electrode closed-end coaxial HPGe detector with 72.5 mm in diameter and 60.5 mm in length, at 0 deg. The proton irradiation current was 50 nA, and the target consisted of 250 μg/cm 2 CaF 2 evaporated on a 0.1 mm Ta backing. In this reaction the 20 Ne resonant state fissions in flight, and the resulting 16 O excited states have different half-lives; all observed peaks are deformed due to either Doppler broadening from 16 O random velocity direction or Doppler shift from nuclei that leave the target toward the vacuum chamber. Moreover, the peak deformations vary with the proton energy. These deformations were modeled by a Monte Carlo simulation that follows the oxygen nuclei in its trajectory until photon emission, considering the changes in spatial

  18. Marvel-ous Dwarfs: Results from Four Heroically Large Simulated Volumes of Dwarf Galaxies

    Science.gov (United States)

    Munshi, Ferah; Brooks, Alyson; Weisz, Daniel; Bellovary, Jillian; Christensen, Charlotte

    2018-01-01

    We present results from high resolution, fully cosmological simulations of cosmic sheets that contain many dwarf galaxies. Together, they create the largest collection of simulated dwarf galaxies to date, with z=0 stellar masses comparable to the LMC or smaller. In total, we have simulated almost 100 luminous dwarf galaxies, forming a sample of simulated dwarfs which span a wide range of physical (stellar and halo mass) and evolutionary properties (merger history). We show how they can be calibrated against a wealth of observations of nearby galaxies including star formation histories, HI masses and kinematics, as well as stellar metallicities. We present preliminary results answering the following key questions: What is the slope of the stellar mass function at extremely low masses? Do halos with HI and no stars exist? What is the scatter in the stellar to halo mass relationship as a function of dwarf mass? What drives the scatter? With this large suite, we are beginning to statistically characterize dwarf galaxies and identify the types and numbers of outliers to expect.

  19. Fluorescence-enhanced optical imaging in large tissue volumes using a gain-modulated ICCD camera

    International Nuclear Information System (INIS)

    Godavarty, Anuradha; Eppstein, Margaret J; Zhang, Chaoyang; Theru, Sangeeta; Thompson, Alan B; Gurfinkel, Michael; Sevick-Muraca, Eva M

    2003-01-01

    A novel image-intensified charge-coupled device (ICCD) imaging system has been developed to perform 3D fluorescence tomographic imaging in the frequency-domain using near-infrared contrast agents. The imager is unique since it (i) employs a large tissue-mimicking phantom, which is shaped and sized to resemble a female breast and part of the extended chest-wall region, and (ii) enables rapid data acquisition in the frequency-domain by using a gain-modulated ICCD camera. Diffusion model predictions are compared to experimental measurements using two different referencing schemes under two different experimental conditions of perfect and imperfect uptake of fluorescent agent into a target. From these experimental measurements, three-dimensional images of fluorescent absorption were reconstructed using a computationally efficient variant of the approximate extended Kalman filter algorithm. The current work represents the first time that 3D fluorescence-enhanced optical tomographic reconstructions have been achieved from experimental measurements of the time-dependent light propagation on a clinically relevant breast-shaped tissue phantom using a gain-modulated ICCD camera

  20. Solar neutrino detection in a large volume double-phase liquid argon experiment

    Energy Technology Data Exchange (ETDEWEB)

    Franco, D.; Agnes, P. [APC, Université Paris Diderot, CNRS/IN2P3, CEA/Irfu, Observatoire de Paris, Sorbonne Paris Cité, Paris 75205 (France); Giganti, C.; Agostino, L.; De Cecco, S., E-mail: dfranco@in2p3.fr, E-mail: cgiganti@lpnhe.in2p3.fr, E-mail: pagnes@in2p3.fr, E-mail: lagostin@lpnhe.in2p3.fr, E-mail: sandro.dececco@lpnhe.in2p3.fr [LPNHE Paris, Université Pierre et Marie Curie, Université Paris Diderot, CNRS/IN2P3, Paris 75252 (France); and others

    2016-08-01

    Precision measurements of solar neutrinos emitted by specific nuclear reaction chains in the Sun are of great interest for developing an improved understanding of star formation and evolution. Given the expected neutrino fluxes and known detection reactions, such measurements require detectors capable of collecting neutrino-electron scattering data in exposures on the order of 1 ktonne-yr, with good energy resolution and extremely low background. Two-phase liquid argon time projection chambers (LAr TPCs) are under development for direct Dark Matter WIMP searches, which possess very large sensitive mass, high scintillation light yield, good energy resolution, and good spatial resolution in all three cartesian directions. While enabling Dark Matter searches with sensitivity extending to the ''neutrino floor'' (given by the rate of nuclear recoil events from solar neutrino coherent scattering), such detectors could also enable precision measurements of solar neutrino fluxes using the neutrino-electron elastic scattering events. Modeling results are presented for the cosmogenic and radiogenic backgrounds affecting solar neutrino detection in a 300 tonne (100 tonne fiducial) LAr TPC operating at LNGS depth (3,800 meters of water equivalent). The results show that such a detector could measure the CNO neutrino rate with ∼15% precision, and significantly improve the precision of the {sup 7}Be and pep neutrino rates compared to the currently available results from the Borexino organic liquid scintillator detector.

  1. Large-scale hydrogen combustion experiments: Volume 2, Data plots: Final report

    International Nuclear Information System (INIS)

    Thompson, R.T.; Torok, R.C.; Randall, D.S.; Sullivan, J.S.; Thompson, L.B.; Haugh, J.J.

    1988-10-01

    Forty large-scale experiments to investigate the combustion behavior of hydrogen during postulated degraded core accidents were conducted in a 16 m (52 ft) diameter sphere. The performance of safety related equipment and cable also was examined. Combustion was initiated by thermal igniters in both premixed hydrogen air-steam atmospheres and during the continuous injection of hydrogen and steam. The effects of steam, igniter location, water sprays, fans and injection rates were studied. Measurements were made of gas concentrations, combustion pressures, temperatures and heat fluxes. Burn fractions and flame speeds also were determined. Near-infrared seeing cameras permitted direct observation of the hydrogen burns. Combustion pressures and temperatures in premixed atmospheres with hydrogen concentrations up to 13 vol% (steam saturated) were less than the theoretical maximum values. Multiple deflagrations were not encountered during continuous hydrogen injection with pre-activated igniters. Moderate pressure rises resulted from diffusion flames. These flames generally were found above the source. Combustion results have been compared to smaller scale experiments. Several safety related equipment items exhibited degraded performance after a number of tests. Most cable samples passed their electrical checks at the end of the test series. These experiments confirm the effectiveness of the deliberate ignition approach to controlling hydrogen. They also provide data for validating computer codes used to predict hydrogen combustion during degraded core accidents, and for assessing the performance of safety related equipment in such environments

  2. Insufficient evidence of benefit regarding mortality due to albumin substitution in HCC-free cirrhotic patients undergoing large volume paracentesis.

    Science.gov (United States)

    Kütting, Fabian; Schubert, Jens; Franklin, Jeremy; Bowe, Andrea; Hoffmann, Vera; Demir, Muenevver; Pelc, Agnes; Nierhoff, Dirk; Töx, Ulrich; Steffen, Hans-Michael

    2017-02-01

    Current guidelines for clinical practice recommend the infusion of human albumin after large volume paracentesis. After inspecting the current evidence behind this recommendation, we decided to conduct a systematic review and meta-analysis in order to address the effect of albumin on mortality and morbidity in the context of large volume paracentesis. We performed a comprehensive search of large databases and abstract books of conference proceedings up to March 15th 2016 for randomized controlled trials, testing the infusion of human albumin against alternatives (vs no treatment, vs plasma expanders; vs vasoconstrictors) in HCC-free patients suffering from cirrhosis. We analyzed these trials with regard to mortality, changes in plasma renin activity (PRA), hyponatremia, renal impairment, recurrence of ascites with consequential re-admission into hospital and additional complications. We employed trial sequential analysis in order to calculate the number of patients required in controlled trials to be able to determine a statistically significant advantage of the administration of one agent over another with regard to mortality. We were able to include 21 trials totaling 1277 patients. While the administration of albumin prevents a rise in PRA as well as hyponatremia, no improvement in strong clinical endpoints such as mortality could be demonstrated. Trial sequential analysis showed that at least 1550 additional patients need to be recruited into RCTs and analyzed with regard to this question in order to detect or disprove a 25% mortality effect. There is insufficient evidence that the infusion of albumin after LVP significantly lowers mortality in HCC-free patients with advanced liver disease. © 2016 Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd.

  3. Comparison of pathogen DNA isolation methods from large volumes of whole blood to improve molecular diagnosis of bloodstream infections.

    Directory of Open Access Journals (Sweden)

    Anne J M Loonen

    Full Text Available For patients suffering from bloodstream infections (BSI molecular diagnostics from whole blood holds promise to provide fast and adequate treatment. However, this approach is hampered by the need of large blood volumes. Three methods for pathogen DNA isolation from whole blood were compared, i.e. an enzymatic method (MolYsis, 1-5 ml, the novel non-enzymatic procedure (Polaris, 1-5 ml, and a method that does not entail removal of human DNA (Triton-Tris-EDTA EasyMAG, 200 µl. These methods were evaluated by processing blood spiked with 0-1000 CFU/ml of Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans. Downstream detection was performed with real-time PCR assays. Polaris and MolYsis processing followed by real-time PCRs enabled pathogen detection at clinically relevant concentrations of 1-10 CFU/ml blood. By increasing sample volumes, concurrent lower cycle threshold (Ct values were obtained at clinically relevant pathogen concentrations, demonstrating the benefit of using larger blood volumes. A 100% detection rate at a concentration of 10 CFU/ml for all tested pathogens was obtained with the Polaris enrichment, whereas comparatively lower detection rates were measured for MolYsis (50-67% and EasyMAG (58-79%. For the samples with a concentration of 1 CFU/ml Polaris resulted in most optimal detection rates of 70-75% (MolYsis 17-50% and TTE-EasyMAG 20-36%. The Polaris method was more reproducible, less labour intensive, and faster (45 minutes (including Qiagen DNA extraction vs. 2 hours (MolYsis. In conclusion, Polaris and MolYsis enrichment followed by DNA isolation and real-time PCR enables reliable and sensitive detection of bacteria and fungi from 5 ml blood. With Polaris results are available within 3 hours, showing potential for improved BSI diagnostics.

  4. Does Size Really Matter? Analysis of the Effect of Large Fibroids and Uterine Volumes on Complication Rates of Uterine Artery Embolisation

    International Nuclear Information System (INIS)

    Parthipun, A. A.; Taylor, J.; Manyonda, I.; Belli, A. M.

    2010-01-01

    The purpose of this study was to determine whether there is a correlation between large uterine fibroid diameter, uterine volume, number of vials of embolic agent used and risk of complications from uterine artery embolisation (UAE). This was a prospective study involving 121 patients undergoing UAE embolisation for symptomatic uterine fibroids at a single institution. Patients were grouped according to diameter of largest fibroid and uterine volume. Results were also stratified according to the number of vials of embolic agent used and rate of complications. No statistical difference in complication rate was demonstrated between the two groups according to diameter of the largest fibroid (large fibroids were classified as ≥10 cm; Fisher's exact test P = 1.00), and no statistical difference in complication rate was demonstrated according to uterine volume (large uterine volume was defined as ≥750 cm 3 ; Fisher's exact test P = 0.70). 84 of the 121 patients had documentation of the number of vials used during the procedure. Patients were divided into two groups, with ≥4 used defined as a large number of embolic agent. There was no statistical difference between these two groups and no associated increased risk of developing complications. This study showed no increased incidence of complications in women with large-diameter fibroids or uterine volumes as defined. In addition, there was no evidence of increased complications according to quantity of embolic material used. Therefore, UAE should be offered to women with large fibroids and uterine volumes.

  5. Study on a new calibration methods of in-situ HPGe γ spectrometers used for non-destructive analyzing radioactivity in nuclear facilities decommissioning

    International Nuclear Information System (INIS)

    Xiao Xuefu; Song Lijun; Wang Yulai; Wen Fuping; Liao Haitao; Ban Ying; Xia Yihua; Li Ruixiang; Li Hang; Tu Xingmin

    2007-06-01

    A new calibration technique, which is the Monte Carlo modeling technique, of in-situ HPGe γ spectrometers used for non-destructive analyzing radioactivity in nuclear facilities decommissioning, is presented. A series of assay for some stainless steel pipes and tanks in some nuclear facilities/laboratories of CIAE are taken on site with the in-situ HPGe γ spectrometer. At the same time, some examples are taken and analyzed in laboratories. The relative bias/variation between the values of activity measured by in-situ HPGe γ spectrometers on site and that analyzed in laboratory is less than ±45.0%. (authors)

  6. Characterization of large volume CdZnTe detectors with a quad-grid structure for the COBRA experiment

    Energy Technology Data Exchange (ETDEWEB)

    Rohatsch, Katja [TU Dresden, Institut fuer Kern- und Teilchenphysik, 01069 Dresden (Germany); Collaboration: COBRA-Collaboration

    2016-07-01

    The COBRA experiment uses room temperature semiconductor detectors made of Cadmium-Zinc-Telluride, which contains several double beta isotopes, to search for neutrinoless double beta-decay. To compensate for poor hole transport in CdZnTe the detectors are equipped with a coplanar grid (CPG) instead of a planar anode. Currently, a demonstrator setup consisting of 64 1 cm{sup 3} CPG-detectors is in operation at the LNGS in Italy to prove the concept and to determine the long-term stability of the detectors and the instrumentation. For a future large scale experiment it is planned to use larger CdZnTe detectors with a volume of 6 cm{sup 3}, because of the better surface-to-volume ratio and the higher full energy detection efficiency. This will also reduce the background contribution of surface contaminations. Before the installation at the LNGS the new detector design is validated and studied in detail. This talk presents a laboratory experiment for the characterization with γ-radiation of 6 cm{sup 3} CdZnTe quad-grid detectors. The anode of such a detector is divided into four sub-CPGs. The characterization routine consists of the determination of the optimal working point and two-dimensional spatially resolved scans with a highly collimated γ-source.

  7. Plasma properties in a large-volume, cylindrical and asymmetric radio-frequency capacitively coupled industrial-prototype reactor

    International Nuclear Information System (INIS)

    Lazović, Saša; Puač, Nevena; Spasić, Kosta; Malović, Gordana; Petrović, Zoran Lj; Cvelbar, Uroš; Mozetič, Miran; Radetić, Maja

    2013-01-01

    We have developed a large-volume low-pressure cylindrical plasma reactor with a size that matches industrial reactors for treatment of textiles. It was shown that it efficiently produces plasmas with only a small increase in power as compared with a similar reactor with 50 times smaller volume. Plasma generated at 13.56 MHz was stable from transition to streamers and capable of long-term continuous operation. An industrial-scale asymmetric cylindrical reactor of simple design and construction enabled good control over a wide range of active plasma species and ion concentrations. Detailed characterization of the discharge was performed using derivative, Langmuir and catalytic probes which enabled determination of the optimal sets of plasma parameters necessary for successful industry implementation and process control. Since neutral atomic oxygen plays a major role in many of the material processing applications, its spatial profile was measured using nickel catalytic probe over a wide range of plasma parameters. The spatial profiles show diffusion profiles with particle production close to the powered electrode and significant wall losses due to surface recombination. Oxygen atom densities range from 10 19 m −3 near the powered electrode to 10 17 m −3 near the wall. The concentrations of ions at the same time are changing from 10 16 to the 10 15 m −3 at the grounded chamber wall. (paper)

  8. Large-volume excitation of air, argon, nitrogen and combustible mixtures by thermal jets produced by nanosecond spark discharges

    Science.gov (United States)

    Stepanyan, Sergey; Hayashi, Jun; Salmon, Arthur; Stancu, Gabi D.; Laux, Christophe O.

    2017-04-01

    This work presents experimental observations of strong expanding thermal jets following the application of nanosecond spark discharges. These jets propagate in a toroidal shape perpendicular to the interelectrode axis, with high velocities of up to 30 m s-1 and over distances of the order of a cm. Their propagation length is much larger than the thermal expansion region produced by the conventional millisecond sparks used in car engine ignition, thus greatly improving the volumetric excitation of gas mixtures. The shape and velocity of the jets is found to be fairly insensitive to the shape of the electrodes. In addition, their spatial extent is found to increase with the number of nanosecond sparks and with the discharge voltage, and to decrease slightly with the pressure between 1 and 7 atm at constant applied voltage. Finally, this thermal jet phenomenon is observed in experiments conducted with many types of gas mixtures, including air, nitrogen, argon, and combustible CH4/air mixtures. This makes nanosecond repetitively pulsed discharges particularly attractive for aerodynamic flow control or plasma-assisted combustion because of their ability to excite large volumes of gas, typically about 100 times the volume of the discharge.

  9. Pretherapy metabolic tumour volume is an independent predictor of outcome in patients with diffuse large B-cell lymphoma

    Energy Technology Data Exchange (ETDEWEB)

    Sasanelli, Myriam; Meignan, Michel; Haioun, Corinne; Itti, Emmanuel [Paris-Est University, Nuclear Medicine and Lymphoid Malignancies Unit, Henri Mondor Hospital, Creteil (France); Berriolo-Riedinger, Alina; Casasnovas, Rene-Olivier [Nuclear Medicine and Hematology, Georges-Francois Leclerc Center, Le Bocage Hospital, Dijon (France); Biggi, Alberto; Gallamini, Andrea [Nuclear Medicine and Hematology, Santa Croce e Carle Hospital, Cuneo (Italy); Siegel, Barry A.; Cashen, Amanda F. [Washington University School of Medicine, Nuclear Medicine and Oncology, Siteman Cancer Center, St. Louis, MO (United States); Vera, Pierre; Tilly, Herve [Nuclear Medicine and Hematology, Henri Becquerel Center, Rouen (France); Versari, Annibale [Nuclear Medicine, Santa Maria Nuova Hospital-IRCCS, Reggio Emilia (Italy)

    2014-11-15

    We investigated the prognostic value of total metabolic tumour volume (TMTV) in diffuse large B-cell lymphoma (DLBCL). TMTV was measured in 114 patients with newly diagnosed DLBCL who underwent {sup 18}F-FDG PET/CT at baseline before immunochemotherapy. TMTV was computed by summing the volumes of all lymphomatous lesions after applying the local SUVmax threshold of 41 % using semiautomatic software. Prognostic value was assessed by Kaplan-Meier estimates of progression-free survival (PFS) and overall survival (OS). Median follow-up was 39 months. Average pretherapy TMTV was 509 ± 568 cm{sup 3}. The 3-year estimates of PFS were 77 % in the low metabolic burden group (TMTV ≤550 cm{sup 3}) and 60 % in the high metabolic burden group (TMTV >550 cm{sup 3}, p = 0.04), and prediction of OS was even better (87 % vs. 60 %, p = 0.0003). Cox regression showed independence of TMTV for OS prediction (p = 0.002) compared with other pretherapy indices of tumour burden, such as tumour bulk and the International Prognostic Index. Pretherapy TMTV is an independent predictor of outcome in patients with DLBCL. (orig.)

  10. Determination of average fission fraction produced by 14 MeV neutrons in assemblies with large volume of depleted uranium

    International Nuclear Information System (INIS)

    Wang Dalun; Li Benci; Wang Xiuchun; Li Yijun; Zhang Shaohua; He Yongwu

    1991-07-01

    The average fission fraction of 238 U caused by 14 MeV neutrons in assemblies with large volume depleted uranium has been determined. The measured value of p f 238U (R ∞ depleted ) 14 was 0.897 ± 0.036. Measurements were also completed for neutron flux distribution and average fission fraction of 235 U isotope in depleted uranium sphere. Values of p f 238U (R depleted ) have been obtained by using a series of uranium spheres. For a sphere with Φ 600 the p f 23 '8 U (R 300 depleted ) is 0.823 ± 0.041, the density of depleted uranium assembly is 18.8g/cm 3 and total weight of assembly is about 2.8t

  11. Heterogeneous asymmetric recombinase polymerase amplification (haRPA) for rapid hygiene control of large-volume water samples.

    Science.gov (United States)

    Elsäßer, Dennis; Ho, Johannes; Niessner, Reinhard; Tiehm, Andreas; Seidel, Michael

    2018-04-01

    Hygiene of drinking water is periodically controlled by cultivation and enumeration of indicator bacteria. Rapid and comprehensive measurements of emerging pathogens are of increasing interest to improve drinking water safety. In this study, the feasibility to detect bacteriophage PhiX174 as a potential indicator for virus contamination in large volumes of water is demonstrated. Three consecutive concentration methods (continuous ultrafiltration, monolithic adsorption filtration, and centrifugal ultrafiltration) were combined to concentrate phages stepwise from 1250 L drinking water into 1 mL. Heterogeneous asymmetric recombinase polymerase amplification (haRPA) is applied as rapid detection method. Field measurements were conducted to test the developed system for hygiene online monitoring under realistic conditions. We could show that this system allows the detection of artificial contaminations of bacteriophage PhiX174 in drinking water pipelines. Copyright © 2018 Elsevier Inc. All rights reserved.

  12. A 5 kA pulsed power supply for inductive and plasma loads in large volume plasma device

    Energy Technology Data Exchange (ETDEWEB)

    Srivastava, P. K., E-mail: pkumar@ipr.res.in; Singh, S. K.; Sanyasi, A. K.; Awasthi, L. M., E-mail: kushagra.lalit@gmail.com; Mattoo, S. K. [Institute for Plasma Research, Gandhinagar (India)

    2016-07-15

    This paper describes 5 kA, 12 ms pulsed power supply for inductive load of Electron Energy Filter (EEF) in large volume plasma device. The power supply is based upon the principle of rapid sourcing of energy from the capacitor bank (2.8 F/200 V) by using a static switch, comprising of ten Insulated Gate Bipolar Transistors (IGBTs). A suitable mechanism is developed to ensure equal sharing of current and uniform power distribution during the operation of these IGBTs. Safe commutation of power to the EEF is ensured by the proper optimization of its components and by the introduction of over voltage protection (>6 kV) using an indigenously designed snubber circuit. Various time sequences relevant to different actions of power supply, viz., pulse width control and repetition rate, are realized through optically isolated computer controlled interface.

  13. Analysis of plant hormones by microemulsion electrokinetic capillary chromatography coupled with on-line large volume sample stacking.

    Science.gov (United States)

    Chen, Zongbao; Lin, Zian; Zhang, Lin; Cai, Yan; Zhang, Lan

    2012-04-07

    A novel method of microemulsion electrokinetic capillary chromatography (MEEKC) coupled with on-line large volume sample stacking was developed for the analysis of six plant hormones including indole-3-acetic acid, indole-3-butyric acid, indole-3-propionic acid, 1-naphthaleneacetic acid, abscisic acid and salicylic acid. Baseline separation of six plant hormones was achieved within 10 min by using the microemulsion background electrolyte containing a 97.2% (w/w) 10 mM borate buffer at pH 9.2, 1.0% (w/w) ethyl acetate as oil droplets, 0.6% (w/w) sodium dodecyl sulphate as surfactant and 1.2% (w/w) 1-butanol as cosurfactant. In addition, an on-line concentration method based on a large volume sample stacking technique and multiple wavelength detection was adopted for improving the detection sensitivity in order to determine trace level hormones in a real sample. The optimal method provided about 50-100 fold increase in detection sensitivity compared with a single MEEKC method, and the detection limits (S/N = 3) were between 0.005 and 0.02 μg mL(-1). The proposed method was simple, rapid and sensitive and could be applied to the determination of six plant hormones in spiked water samples, tobacco leaves and 1-naphthylacetic acid in leaf fertilizer. The recoveries ranged from 76.0% to 119.1%, and good reproducibilities were obtained with relative standard deviations (RSDs) less than 6.6%.

  14. Enrichment of circulating tumor cells from a large blood volume using leukapheresis and elutriation: proof of concept.

    Science.gov (United States)

    Eifler, Robert L; Lind, Judith; Falkenhagen, Dieter; Weber, Viktoria; Fischer, Michael B; Zeillinger, Robert

    2011-03-01

    The aim of this study was to determine the applicability of a sequential process using leukapheresis, elutriation, and fluorescence-activated cell sorting (FACS) to enrich and isolate circulating tumor cells from a large blood volume to allow further molecular analysis. Mononuclear cells were collected from 10 L of blood by leukapheresis, to which carboxyfluorescein succinimidyl ester prelabeled CaOV-3 tumor cells were spiked at a ratio of 26 to 10⁶ leukocytes. Elutriation separated the spiked leukapheresates primarily by cell size into distinct fractions, and leukocytes and tumor cells, characterized as carboxyfluorescein succinimidyl ester positive, EpCAM positive and CD45 negative events, were quantified by flow cytometry. Tumor cells were isolated from the last fraction using FACS or anti-EpCAM coupled immunomagnetic beads, and their recovery and purity determined by fluorescent microscopy and real-time PCR. Leukapheresis collected 13.5 x 10⁹ mononuclear cells with 87% efficiency. In total, 53 to 78% of spiked tumor cells were pre-enriched in the last elutriation fraction among 1.6 x 10⁹ monocytes. Flow cytometry predicted a circulating tumor cell purity of ~90% giving an enrichment of 100,000-fold following leukapheresis, elutriation, and FACS, where CaOV-3 cells were identified as EpCAM positive and CD45 negative events. FACS confirmed this purity. Alternatively, immunomagnetic bead adsorption recovered 10% of tumor cells with a median purity of 3.5%. This proof of concept study demonstrated that elutriation and FACS following leukapheresis are able to enrich and isolate tumor cells from a large blood volume for molecular characterization. Copyright © 2010 International Clinical Cytometry Society.

  15. Calibration of a HPGe detector for Marinelli vessel geometry for measurement of gaseous 41Ar activity using MCNP

    International Nuclear Information System (INIS)

    Raghunath, T.; Narasimhanath, V.; Sunil, C.N.; Kumaravel, S.; Ramakrishna, V.; Prashanth Kumar, M.; Nair, B.S.K.; Purohit, R.G.; Sarkar, P.K.

    2012-01-01

    To carry out measurement of 41 Ar gaseous activity an attempt is made to calibrate the detector (HPGe) for Standard Measuring Flask (SMF) and Marinelli vessel geometry and compare their efficiencies. As standard gaseous source of 41 Ar is not available the calibration is done using liquid standard source of 22 Na (having 1274.5 KeV gamma energy close to the 1293.6 KeV gamma energy of 41 Ar). The HPGe detector and both the geometries are simulated and efficiencies for Full Energy Peak (FEP) are obtained using MCNP. The correction factor for energy and sample matrix is obtained from simulated efficiencies. By applying these correction factors the calibration is done. (author)

  16. A Comparison between HPGe and NaI(Tl) detectors performance for gamma-spectrometry of low level measurement

    International Nuclear Information System (INIS)

    Poursiamy, N. H.; Tajikahmadi, H.; Mirshojaei, S. F.

    2005-01-01

    According to progressive usage of nuclear technology, it's important to prevent the contamination of the environment by man-made radioisotopes and exposures of human being. Radioisotopes can enter the human body by inhalation and ingestion which are the most important ways to internal exposures. Measurement of radiation level in foodstuff is one of the most important parameters in environmental safety which is performed according to constitution and standard tests in most countries such as Iran. Gamma spectrometry is carried out by NaI(Tl) and HPGe detector systems for foodstuffs. In this research operation of HPGe and NaI(Tl) detectors in gamma spectrometry with a standard radioactive source are investigated and compared. Also the result of NaI superiority in foodstuff radiation measurement given

  17. A fitting algorithm based on simulated annealing techniques for efficiency calibration of HPGe detectors using different mathematical functions

    Energy Technology Data Exchange (ETDEWEB)

    Hurtado, S. [Servicio de Radioisotopos, Centro de Investigacion, Tecnologia e Innovacion (CITIUS), Universidad de Sevilla, Avda. Reina Mercedes s/n, 41012 Sevilla (Spain)], E-mail: shurtado@us.es; Garcia-Leon, M. [Departamento de Fisica Atomica, Molecular y Nuclear, Facultad de Fisica, Universidad de Sevilla, Aptd. 1065, 41080 Sevilla (Spain); Garcia-Tenorio, R. [Departamento de Fisica Aplicada II, E.T.S.A. Universidad de Sevilla, Avda, Reina Mercedes 2, 41012 Sevilla (Spain)

    2008-09-11

    In this work several mathematical functions are compared in order to perform the full-energy peak efficiency calibration of HPGe detectors using a 126cm{sup 3} HPGe coaxial detector and gamma-ray energies ranging from 36 to 1460 keV. Statistical tests and Monte Carlo simulations were used to study the performance of the fitting curve equations. Furthermore the fitting procedure of these complex functional forms to experimental data is a non-linear multi-parameter minimization problem. In gamma-ray spectrometry usually non-linear least-squares fitting algorithms (Levenberg-Marquardt method) provide a fast convergence while minimizing {chi}{sub R}{sup 2}, however, sometimes reaching only local minima. In order to overcome that shortcoming a hybrid algorithm based on simulated annealing (HSA) techniques is proposed. Additionally a new function is suggested that models the efficiency curve of germanium detectors in gamma-ray spectrometry.

  18. The Viking viewer for connectomics: scalable multi-user annotation and summarization of large volume data sets.

    Science.gov (United States)

    Anderson, J R; Mohammed, S; Grimm, B; Jones, B W; Koshevoy, P; Tasdizen, T; Whitaker, R; Marc, R E

    2011-01-01

    Modern microscope automation permits the collection of vast amounts of continuous anatomical imagery in both two and three dimensions. These large data sets present significant challenges for data storage, access, viewing, annotation and analysis. The cost and overhead of collecting and storing the data can be extremely high. Large data sets quickly exceed an individual's capability for timely analysis and present challenges in efficiently applying transforms, if needed. Finally annotated anatomical data sets can represent a significant investment of resources and should be easily accessible to the scientific community. The Viking application was our solution created to view and annotate a 16.5 TB ultrastructural retinal connectome volume and we demonstrate its utility in reconstructing neural networks for a distinctive retinal amacrine cell class. Viking has several key features. (1) It works over the internet using HTTP and supports many concurrent users limited only by hardware. (2) It supports a multi-user, collaborative annotation strategy. (3) It cleanly demarcates viewing and analysis from data collection and hosting. (4) It is capable of applying transformations in real-time. (5) It has an easily extensible user interface, allowing addition of specialized modules without rewriting the viewer. © 2010 The Authors Journal of Microscopy © 2010 The Royal Microscopical Society.

  19. Placement of HPGE detectors for whole body counting applications using simulations of voxel phantoms

    International Nuclear Information System (INIS)

    Marzocchi, O.; Breustedt, B.; Zankl, M.

    2010-01-01

    The partial body counter at KIT is going to be rebuilt in order to replace the old Ge detectors with four new HPGe detectors. The new installation will also add whole body capabilities to the system, thanks to an improved mechanics able to position the detectors with a high degree of freedom in the chamber. During the definition of the position of the detectors a compromise between the opposite goals of high efficiency and small dependence of the detection efficiency on the position of the source had to be sought. High detection efficiency involves placing the detector near the skin, where the photon flux is maximal, while the second goal involves placing the detectors at a greater distance from the body. The same concept was applied during the definition of the partial body measurement configurations, but the goal was the increase of the specificity of the measurement. In addition, the mechanical installation poses some constraints: two detectors are mounted on carts and therefore can be placed independently around the subjects, but not in front of it, while the other two detectors are mounted on carts hanging from the same rail on the ceiling, therefore their distance from the subject is constrained by the maximum offset between them. (orig.)

  20. Upgrade of the muon veto and current status of the Dortmund low background HPGe facility

    Energy Technology Data Exchange (ETDEWEB)

    Goessling, Claus; Kroeninger, Kevin; Neddermann, Till; Nitsch, Christian; Quante, Thomas [TU Dortmund, Physik EIV, D-44221 Dortmund (Germany)

    2015-07-01

    The Dortmund Low Background HPGe Facility (DLB) is a germanium facility with heavy shielding located above ground. It's primary task is to provide material screening support for the COBRA experiment which was built to search for neutrinoless double beta decay. Germanium detectors used for low background gamma spectroscopy are usually operated under either a fairly low overburden (O(1m) water equivalent (mwe)) or high overburden, e.g. in specialised underground laboratories (O(>100 mwe)). In between, only a few facilities exist, such as the DLB. The artificial overburden of 10 mwe already shields the weak component of cosmic rays. The lead castle with a state-of-the-art neutron shielding as well as the active anti-cosmics veto detector enable low background gamma spectrometry with the advantage of good accessibility on the university campus. Throughout the last years improvements have been made especially on the cosmics veto and the MC simulation leading to an remarkable low integral background counting rate (40-2700 keV) of about 2.5228(52) counts/kg/min. The talk summarises the completed tasks and presents the current status.

  1. Methods for fitting of efficiency curves obtained by means of HPGe gamma rays spectrometers

    International Nuclear Information System (INIS)

    Cardoso, Vanderlei

    2002-01-01

    The present work describes a few methodologies developed for fitting efficiency curves obtained by means of a HPGe gamma-ray spectrometer. The interpolated values were determined by simple polynomial fitting and polynomial fitting between the ratio of experimental peak efficiency and total efficiency, calculated by Monte Carlo technique, as a function of gamma-ray energy. Moreover, non-linear fitting has been performed using a segmented polynomial function and applying the Gauss-Marquardt method. For the peak area obtainment different methodologies were developed in order to estimate the background area under the peak. This information was obtained by numerical integration or by using analytical functions associated to the background. One non-calibrated radioactive source has been included in the curve efficiency in order to provide additional calibration points. As a by-product, it was possible to determine the activity of this non-calibrated source. For all fittings developed in the present work the covariance matrix methodology was used, which is an essential procedure in order to give a complete description of the partial uncertainties involved. (author)

  2. An automated measuring system based on gamma spectrometry with HPGe detectors

    International Nuclear Information System (INIS)

    Mala, Helena; Rulik, Petr; Hyza, Miroslav; Dragounova, Lenka; Helebrant, Jan; Hroznicek, Marek; Jelinek, Pavel; Zak, Jan

    2016-01-01

    An automatic system for unattended gamma spectrometric measurements of bulk samples ( “Gamma Automat”, GA) was developed by the National Radiation Protection Institute and Nuvia, Inc. as a part of a research project. The basic parts include a detection system with two HPGe detectors in the lead shielded chambers, sample changer, sample tray and a control unit. The GA enables counting in two geometries: (i) with cylindrical containers (200 ml) either one placed at the detector face or 2-6 placed around the detector or (II) with Marinelli beakers (600 ml). The shelf can accommodate 180 cylindrical containers or 54 Marinelli beakers. Samples are changed by a robotic arm. The sample data and the analysis required are passed to the GA by a matrix code (generated within the laboratory system) located on the lid of a sample container, whence the GA reads information. Spectrometric analysis is performed automatically after the counting. Current status of GA can be remotely monitored. Information about the activities of the GA, measurement completion or failures of the equipment are automatically generated and sent to a mobile phone and the operator PC. A presentation of the GA is available at https://youtu.be/1lQhfo0Fljo. (orig.)

  3. Influence of the geometrical characteristics of an HpGe detector on its efficiency

    International Nuclear Information System (INIS)

    Vargas, M.J.; Timon, A.F.; Sanchez, D.P.

    2002-01-01

    Computer codes based on Monte Carlo calculations have been extensively developed for the computation of the efficiency in gamma-ray spectrometry. The errors in the specific parameters of the detector due to the lack of precise knowledge of its characteristics usually represent one of the most important sources of inaccuracy in this simulation technique. Influence of several detector parameters on the efficiency for a typical coaxial n-type HpGe detector is presented. Calculations of the full-energy peak efficiencies were performed by means of a Monte Carlo code in the range 122-1836 keV for several types of source configuration: point source, cellulose filter, and two different cylindrical boxes containing a solid matrix of SiO 2 . The detector parameters varied were the crystal diameter, crystal height, diameter of the internal core, and the position of the crystal with respect to the beryllium window. Significant deviations in the efficiency, depending on the source geometry and the photon energy, can be produced by varying only slightly some of the detector parameters. (author)

  4. Evaluation of real-time digital pulse shapers with various HPGe and silicon radiation detectors

    International Nuclear Information System (INIS)

    Menaa, N.; D'Agostino, P.; Zakrzewski, B.; Jordanov, V.T.

    2011-01-01

    Real-time digital pulse shaping techniques allow synthesis of pulse shapes that have been difficult to realize using the traditional analog methods. Using real-time digital shapers, triangular/trapezoidal filters can be synthesized in real time. These filters exhibit digital control on the rise time, fall time, and flat-top of the trapezoidal shape. Thus, the trapezoidal shape can be adjusted for optimum performance at different distributions of the series and parallel noise. The trapezoidal weighting function (WF) represents the optimum time-limited pulse shape when only parallel and series noises are present in the detector system. In the presence of 1/F noise, the optimum WF changes depending on the 1/F noise contribution. In this paper, we report on the results of the evaluation of new filter types for processing signals from CANBERRA high purity germanium (HPGe) and passivated, implanted, planar silicon (PIPS) detectors. The objective of the evaluation is to determine improvements in performance over the current trapezoidal (digital) filter. The evaluation is performed using a customized CANBERRA digital signal processing unit that is fitted with new FPGA designs and any required firmware modifications to support operation of the new filters. The evaluated filters include the Cusp, one-over-F (1/F), and pseudo-Gaussian filters. The results are compared with the CANBERRA trapezoidal shaper.

  5. Status of the development of a HPGe-BGO pair spectrometer for ELI-NP

    Energy Technology Data Exchange (ETDEWEB)

    Homm, Ilja; Ignatov, Alexander; Ilieva, Stoyanka; Kroell, Thorsten [Technische Universitaet Darmstadt, Darmstadt (Germany)

    2016-07-01

    At the moment, the new European research facility called ELI-NP (The Extreme Light Infrastructure - Nuclear Physics) is being built in Bucharest-Magurele, Romania. It is one of three parts of the ELI project and offers applications for the investigation of questions concerning nuclear physics. The 8 HPGe (High-Purity Germanium) CLOVER detectors of ELIADE (ELI-NP Array of DEtectors) with four crystals each and high resolution are important components for the gamma spectroscopic study of photonuclear reactions. These detectors are surrounded by standard anti-Compton shields (AC shield). We investigate the possibility to operate for two of the ELIADE CLOVERS an advanced version of an AC shield as escape γ-rays pair spectrometers to extend the high-resolution spectroscopy to photon energies of several MeV where the pair production process dominates. The main tasks in this work are to develop and test such an AC shield: a pair spectrometer with BGO and CsI(Tl) crystals with APD (avalanche photodiode) or SPM (silicon photomultiplier) readout. The results of prototype testing are reported.

  6. Measurement of the pulse pileup correction for the HPGe gamma spectrometer

    International Nuclear Information System (INIS)

    Kulkarni, D.B.; Anuradha, R.; Joseph, Leena; Kulkarni, M.S.

    2018-01-01

    Radiation Standards Section (RSS), RSSD, has HPGe gamma spectrometry system maintained as a secondary standard for standardization of gamma emitting radionuclides. This system is also used to detect the impurities in the radioactivity samples supplied for the international inter-comparison exercises, so that the appropriate correction can be made for the standardized activity of principle radionuclide. The system is calibrated as per the recommended procedure (ANSI standard N42.14, 1999). As a part of this calibration, measurement of the pulse pile up correction was carried out in the energy range of 81 keV to 1408 keV. The measurement of pileup correction is very important for the standardization of sources having higher counting rates where the extent of the pileup effect is more and considerable deviation from the true counting rates was observed. For these sources the measured photo peak counting rate is less than true counting rate and needs to be corrected for pileup effect. The details of experiments are discussed in this paper

  7. Comparison of MCNP and Experimental Measurements for an HPGe-based Spectroscopy Portal Monitor

    International Nuclear Information System (INIS)

    Keyser, Ronald M.; Hensley, Walter K.; Twomey, Timothy R.; UPP, Daniel L.

    2008-01-01

    The necessity to monitor international commercial transportation for illicit nuclear materials resulted in the installation of many nuclear radiation detection systems in Portal Monitors. These were mainly gross counters which alarmed at any indication of high radioactivity in the shipment, the vehicle or even the driver. The innocent alarm rate, due to legal shipments of sources and NORM, or medical isotopes in patients, caused interruptions and delays in commerce while the legality of the shipment was verified. To overcome this difficulty, Department of Homeland Security (DHS) supported the writing of the ANSI N42.38 standard (Performance Criteria for Spectroscopy-Based Portal Monitors used for Homeland Security) to define the performance of a Portal Monitor with nuclide identification capabilities, called a Spectroscopy Portal Monitor. This standard defines detection levels and response characteristics for the system for energies from 25 keV to 3 MeV. To accomplish the necessary performance, several different HPGe detector configurations were modeled using MCNP for the horizontal field of view (FOV) and vertical linearity of response over the detection zone of 5 meters by 4.5 meters for 661 keV as representative of the expected nuclides of interest. The configuration with the best result was built and tested. The results for the FOV as a function of energy and the linearity show good agreement with the model and performance exceeding the requirements of N42.38

  8. In situ prompt gamma-ray measurement of river water salinity in northern Taiwan using HPGe-252Cf probe

    International Nuclear Information System (INIS)

    Jiunnhsing Chao; Chien Chung

    1991-01-01

    A portable HPGe- 252 Cf probe dedicated to in situ survey of river water salinity was placed on board a fishing boat to survey the Tamsui River in northern Taiwan. The variation of water salinity is surveyed by measuring the 6111 keV chlorine prompt photopeak along the river. Results indicate that the probe can be used as a salinometer for rapid, in situ measurement in polluted rivers or sea. (author)

  9. Assessment of applicability of portable HPGe detector with in situ object counting system based on performance evaluation of thyroid radiobioassays

    Energy Technology Data Exchange (ETDEWEB)

    Park, Min Seok; Kwon, Tae Eun; Pak, Min Jung; Park, Se Young; Ha, Wi Ho; Jin, Young Woo [National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of)

    2017-06-15

    Different cases exist in the measurement of thyroid radiobioassays owing to the individual characteristics of the subjects, especially the potential variation in the counting efficiency. An In situ Object Counting System (ISOCS) was developed to perform an efficiency calibration based on the Monte Carlo calculation, as an alternative to conventional calibration methods. The purpose of this study is to evaluate the applicability of ISOCS to thyroid radiobioassays by comparison with a conventional thyroid monitoring system. The efficiency calibration of a portable high-purity germanium (HPGe) detector was performed using ISOCS software. In contrast, the conventional efficiency calibration, which needed a radioactive material, was applied to a scintillator-based thyroid monitor. Four radioiodine samples that contained 125I and 131I in both aqueous solution and gel forms were measured to evaluate radioactivity in the thyroid. ANSI/HPS N13.30 performance criteria, which included the relative bias, relative precision, and root-mean-squared error, were applied to evaluate the performance of the measurement system. The portable HPGe detector could measure both radioiodines with ISOCS but the thyroid monitor could not measure 125I because of the limited energy resolution of the NaI(Tl) scintillator. The 131I results from both detectors agreed to within 5% with the certified results. Moreover, the 125I results from the portable HPGe detector agreed to within 10% with the certified results. All measurement results complied with the ANSI/HPS N13.30 performance criteria. The results of the intercomparison program indicated the feasibility of applying ISOCS software to direct thyroid radiobioassays. The portable HPGe detector with ISOCS software can provide the convenience of efficiency calibration and higher energy resolution for identifying photopeaks, compared with a conventional thyroid monitor with a NaI(Tl) scintillator. The application of ISOCS software in a radiation

  10. Characterization of the first true coaxial 18-fold segmented n-type prototype HPGe detector for the gerda project

    International Nuclear Information System (INIS)

    Abt, I.; Caldwell, A.; Gutknecht, D.; Kroeninger, K.; Lampert, M.; Liu, X.; Majorovits, B.; Quirion, D.; Stelzer, F.; Wendling, P.

    2007-01-01

    The first true coaxial 18-fold segmented n-type HPGe prototype detector produced by Canberra-France for the GERDA neutrinoless double beta-decay project was tested both at Canberra-France and at the Max-Planck-Institut fur Physik in Munich. The main characteristics of the detector are given and measurements concerning detector properties are described. A novel method to establish contacts between the crystal and a Kapton cable is presented

  11. THE IMPORTANCE OF INFORMATION SYSTEMS IN THE MANAGEMENT AND PROCESSING OF LARGE DATA VOLUMES IN PUBLIC INSTITUTIONS

    Directory of Open Access Journals (Sweden)

    CARINA-ELENA STEGĂROIU

    2016-12-01

    Full Text Available Under a computerized society, technological resources become a source of identification for any community, institution or country. Globalization of information becomes a reality, all the resources having entered into a relationship of subordination with the World Wide Web, the information highways and the Internet. "Information technology - with its most important branch, data management computer science - enters a new era, in which the computer leads to the benefit of a navigable and transparent communication space, focusing on information". Therefore, in an information-based economy, information systems have been established which, based on management systems through the methods of algebra, with applications in economic engineering, have come to manage and process large volumes of data, especially in public institutions. Consequently, the Ministry of Public Affairs has implemented the “Increasing the public administration’s responsibility by modernising the information systems for generating the reports of the financial situations of public institutions” project (FOREXEBUG”, cod SMIS 34952, for which it received in 2012 non-refundable financing from the European Social Fund through the Operational Program for Developing the Administrative Capacity 2007-2013, based on which this paper will analyse the usefulness of implementing such a program in public institutions. Such a system aims to achieve a new form of reporting of budget execution and financial statements (including information related to legal commitments submitted monthly by each public institution in electronic, standardized, secure form, with increasing the reliability of data collected by cross-checking data from the treasury and providing reliable information for use by the Ministry of Finance, public institutions, other relevant institutions and the public, both at the level of detail and the consolidation possibilities at various levels, in parallel with their use for

  12. SU-F-T-368: Improved HPGe Detector Precise Efficiency Calibration with Monte Carlo Simulations and Radioactive Sources

    Energy Technology Data Exchange (ETDEWEB)

    Zhai, Y. John [Vanderbilt University, Vanderbilt-Ingram Cancer Center, Nashville, TN 37232 (United States)

    2016-06-15

    Purpose: To obtain an improved precise gamma efficiency calibration curve of HPGe (High Purity Germanium) detector with a new comprehensive approach. Methods: Both of radioactive sources and Monte Carlo simulation (CYLTRAN) are used to determine HPGe gamma efficiency for energy range of 0–8 MeV. The HPGe is a GMX coaxial 280 cm{sup 3} N-type 70% gamma detector. Using Momentum Achromat Recoil Spectrometer (MARS) at the K500 superconducting cyclotron of Texas A&M University, the radioactive nucleus {sup 24} Al was produced and separated. This nucleus has positron decays followed by gamma transitions up to 8 MeV from {sup 24} Mg excited states which is used to do HPGe efficiency calibration. Results: With {sup 24} Al gamma energy spectrum up to 8MeV, the efficiency for γ ray 7.07 MeV at 4.9 cm distance away from the radioactive source {sup 24} Al was obtained at a value of 0.194(4)%, by carefully considering various factors such as positron annihilation, peak summing effect, beta detector efficiency and internal conversion effect. The Monte Carlo simulation (CYLTRAN) gave a value of 0.189%, which was in agreement with the experimental measurements. Applying to different energy points, then a precise efficiency calibration curve of HPGe detector up to 7.07 MeV at 4.9 cm distance away from the source {sup 24} Al was obtained. Using the same data analysis procedure, the efficiency for the 7.07 MeV gamma ray at 15.1 cm from the source {sup 24} Al was obtained at a value of 0.0387(6)%. MC simulation got a similar value of 0.0395%. This discrepancy led us to assign an uncertainty of 3% to the efficiency at 15.1 cm up to 7.07 MeV. The MC calculations also reproduced the intensity of observed single-and double-escape peaks, providing that the effects of positron annihilation-in-flight were incorporated. Conclusion: The precision improved gamma efficiency calibration curve provides more accurate radiation detection and dose calculation for cancer radiotherapy treatment.

  13. P08.52 Proton therapy re-Irradiation in large-volume recurrent glioblastoma.

    Science.gov (United States)

    Amelio, D.; Widesott, L.; Vennarini, S.; Fellin, F.; Maines, F.; Righetto, R.; Lorentini, S.; Farace, P.; Schwarz, M.; Amichetti, M.

    2016-01-01

    Abstract Purpose: To report preliminary results of re-irradiation with proton therapy (PT) in large-volume recurrent glioblastoma (rGBM). Matherial/Methods: Between January and December 2015 ten patients (pts) with rGBM were re-irradiated with PT. All pts were previously treated with photon radiotherapy (60 Gy) with concomitant and adjuvant TMZ for 1–20 cycles (median, 7). Seven pts were re-irradiated at first relapse/progression. Four patients were re-irradiated after partial tumor resection. Median age and Karnofsky performance status at re-irradiation were 57 years (range, 41–68) and 80%, (range, 70–100), respectively. Median time between prior radiotherapy and PT was 9 months (range, 5–24). Target definition was based on CT, MR, and 18F-DOPA PET imaging. GTV included any area of contrast enhancement after contrast medium administration plus any pathological PET uptake regions. CTV was generated by adding to GTV a 3-mm uniform margin manually corrected in proximity of anatomical barriers. CTV was expanded by 4 mm to create PTV. Median PTV volume was 90 cc (range, 46–231). All pts received 36 GyRBE in 18 fractions. Four pts also received concomitant temozolomide (75 mg/m2/die, 7 days/week). All pts were treated with active beam scanning PT using 2–3 fields with single field optimization technique. Results: All pts completed the treatment without breaks. Registered acute side effects (according to Common Terminology Criteria for Adverse Events version 4.0 - CTCAE) include grade 1–2 skin erythema, alopecia, fatigue, conjunctivitis, concentration impairment, dysphasia, and headache. There were no grade 3 or higher toxicities. One patient developed grade 1 neutropenia. Five pts started PT under steroids (2–7 mg/daily); two of them reduced the dose during PT, while three kept the same steroids dose. None of remaining pts needed steroids therapy. Registered late side effects (according to CTCAE version 4.0) include grade 1–2 alopecia, fatigue

  14. Study of n-γ discrimination by digital charge comparison method for a large volume liquid scintillator

    International Nuclear Information System (INIS)

    Moszynski, M.; Costa, G.J.; Guillaume, G.; Heusch, B.; Huck, A.; Ring, C.; Bizard, G.; Durand, D.; Peter, J.; Tamain, B.; El Masri, Y.; Hanappe, F.

    1992-01-01

    The study of the n-γ discrimination for a large 41 volume BC501A liquid scintillator coupled to a 130 mm diameter XP4512B photomultiplier was carried out by digital charge comparison method. A very good n-γ discrimination down to 100 keV of recoil electron energy was achieved. The measured relative intensity of the charge integrated at the slow component of the scintillation pulse and the photoelectron yield of the tested counter allow the factor of merit of the n-γ discrimination spectra to be calculated and to be compared with those measured experimentally. This shows that the main limitation of the n-γ discrimination is associated with the statistical fluctuation of the photoelectron number at the slow component. A serious effect of the distortion in the cable used to send the photomultiplier pulse to the electronics for the n-γ discrimination was studied. This suggests that the length of RG58 cable should be limited to about 40 m to preserve a high quality n-γ discrimination. (orig.)

  15. APS 6BM-B Large Volume High Pressure Beamline: A Workhorse for Rock and Mineral Physics

    Science.gov (United States)

    Chen, H.; Whitaker, M. L.; Baldwin, K. J.; Huebsch, W. R.; Vaughan, M. T.; Weidner, D. J.

    2017-12-01

    With the inheritance of decades of technical innovations at the NSLS X17B2 Beamline, APS 6BM-B Beamline was established in 2015 and is a dedicated beamline for synchrotron-based large volume high pressure research in earth sciences, especially rock and mineral physics. Currently a 250-ton hydraulic press equipped with a D-DIA module is installed and a Rotational Drickamer Apparatus from Yale University is hosted every cycle, covering a pressure range from crust to lower mantle. 6BM-B operates in white beam mode with an effective energy range of 20-100 keV. Energy dispersive X-ray diffraction data is collected using a 10-element solid state Ge array detector arranged in a circular geometry to allow for the real time assessment of stress. Direct radiographic imaging using Prosillica CCD camera and scintillating YAG crystals yields sample strain and strain rate. In addition to applications in phase transitions, equation of states measurements, sound velocity measurements, this setup is ideal for studies of steady state and dynamic deformation process. In this presentation, technical features and strengths of 6BM-B will be discussed. Most recent progress and science highlights of our user community will be showcased.

  16. Solid-Phase Extraction and Large-Volume Sample Stacking-Capillary Electrophoresis for Determination of Tetracycline Residues in Milk

    Directory of Open Access Journals (Sweden)

    Gabriela Islas

    2018-01-01

    Full Text Available Solid-phase extraction in combination with large-volume sample stacking-capillary electrophoresis (SPE-LVSS-CE was applied to measure chlortetracycline, doxycycline, oxytetracycline, and tetracycline in milk samples. Under optimal conditions, the proposed method had a linear range of 29 to 200 µg·L−1, with limits of detection ranging from 18.6 to 23.8 µg·L−1 with inter- and intraday repeatabilities < 10% (as a relative standard deviation in all cases. The enrichment factors obtained were from 50.33 to 70.85 for all the TCs compared with a conventional capillary zone electrophoresis (CZE. This method is adequate to analyze tetracyclines below the most restrictive established maximum residue limits. The proposed method was employed in the analysis of 15 milk samples from different brands. Two of the tested samples were positive for the presence of oxytetracycline with concentrations of 95 and 126 µg·L−1. SPE-LVSS-CE is a robust, easy, and efficient strategy for online preconcentration of tetracycline residues in complex matrices.

  17. Safety Analysis in Large Volume Vacuum Systems Like Tokamak: Experiments and Numerical Simulation to Analyze Vacuum Ruptures Consequences

    Directory of Open Access Journals (Sweden)

    A. Malizia

    2014-01-01

    Full Text Available The large volume vacuum systems are used in many industrial operations and research laboratories. Accidents in these systems should have a relevant economical and safety impact. A loss of vacuum accident (LOVA due to a failure of the main vacuum vessel can result in a fast pressurization of the vessel and consequent mobilization dispersion of hazardous internal material through the braches. It is clear that the influence of flow fields, consequence of accidents like LOVA, on dust resuspension is a key safety issue. In order to develop this analysis an experimental facility is been developed: STARDUST. This last facility has been used to improve the knowledge about LOVA to replicate a condition more similar to appropriate operative condition like to kamaks. By the experimental data the boundary conditions have been extrapolated to give the proper input for the 2D thermofluid-dynamics numerical simulations, developed by the commercial CFD numerical code. The benchmark of numerical simulation results with the experimental ones has been used to validate and tune the 2D thermofluid-dynamics numerical model that has been developed by the authors to replicate the LOVA conditions inside STARDUST. In present work, the facility, materials, numerical model, and relevant results will be presented.

  18. Evaluation of thermal stress in the anode chamber wall of a large volume magnetic bucket ion source

    International Nuclear Information System (INIS)

    Wells, Russell; Horiike, Hiroshi; Kuriyama, Masaaki; Ohara, Yoshihiro

    1984-02-01

    Thermal stress analysis was performed on the plasma chamber of the Large Volume Magnetic Multipole Bucket Ion Source (LVB) designed for use on the JT-60 NBI system. The energy absorbed by the walls of the plasma chambers of neutral beam injectors is of the order of 1% of the accelerator electrical drain power. A previous study indicates that a moderately high heat flux, of about 600W/cm 2 , is concentrated on the magnetic field cusp lines during normal full power operation. Abnormal arc discharges during conditioning of a stainless steel LVB produced localized melting of the stainless steel at several locations near the cusps lines. The power contained in abnormal arc discharges (arc spots) was estimated from the observed melting. Thermal stress analysis was performed numerically on representative sections of the copper LVB design for both stable and abnormal arc discharge conditions. Results show that this chamber should not fail due to thermal fatigue stesses arising from normal arc discharges. However, fatigue failure may occur after several hundred to a few thousand arc spots of 30mS duration at any one location. Limited arc discharge operation of the copper bucket was performed to partially verify the chamber's durability. (author)

  19. Development of large-volume, high-resolution tracking detectors based on capillaries filled with liquid scintillator

    International Nuclear Information System (INIS)

    Buontempo, S.; Fabre, J.P.; Frenkel, A.; Gregoire, G.; Hoepfner, K.; Konijn, J.; Kozarenko, E.; Kreslo, I.; Kushnirenko, A.; Martellotti, G.; Michel, L.; Mondardini, M.R.; Penso, G.; Siegmund, W.P.; Strack, R.; Tyukov, V.; Vasilchenko, V.; Vilain, P.; Wilquet, G.; Winter, K.; Wong, H.; Zymin, K.

    1995-01-01

    Searches for the decay of short-lived particles require real time, high-resolution tracking in active targets, which in the case of neutrino physics should be of large volume. The possibility of achieving this by using glass capillaries filled with organic liquid scintillator is being investigated in the framework of the CHORUS experiment at CERN. In this paper, after outlining the application foreseen, advances in the tracking technique are discussed and results from tests are reported. An active target of dimensions 180x2x2 cm 3 has been assembled from capillaries with 20 μm diameter pores. The readout scheme currently in operation allows the reading of similar 5x10 5 channels using a single chain of image intensifiers having a resolution of σ similar 20 μm. Following the development of new liquid scintillators and purification methods an attenuation length of similar 3 m has been obtained. This translates into a hit density of 3.5 per mm for a minimum-ionizing particle that crosses the active target at a distance of 1 m from the readout end. (orig.)

  20. An analysis of the potassium concentrations of soft drinks by HPGe gamma spectrometry

    International Nuclear Information System (INIS)

    Guillermo Espinosa; Jose-Ignacio Golzarri; Ilsa Hernandez-Ibinarriaga

    2009-01-01

    Potassium, in a variety of compounds, occurs in abundance in the Earth's crust, and is an essential nutrient for human health. A naturally occurring radioactive isotope of potassium, 40 K, is found in the food and water that we consume. This paper presents the results of a gamma spectrometry analysis of the 40 K concentrations of a selection of commercial soft drinks. The 40 K concentrations are used to calculate the overall potassium concentrations. The analysis was carried out using a hyper-pure germanium (HPGe) detector with Ortec R ASPEC-927 multichannel analyzer module and GammaVision R software. This system was chosen for its high resolution and automatic data processing. The carbonated soft drinks (sodas) Coca-Cola R , Coca-Cola Light R (sold as Diet Coke R in the USA and other countries), Coca-Cola Zero R , Pepsi R , Pepsi Light R , Pepsi Max R , Big Cola R , Lulu-Cola R , Manzana Lift R , Sprite R and Fanta R and the mineral waters Ciel R and Penafiel R were analyzed. These brands are all international registered trademarks. The products analyzed were manufactured and bottled in Mexico. The results show a great variety of potassium concentrations in the different soft drinks analyzed (from 128.0 to 1113.1 mg/L). The concentration of potassium in the sodas, in conjunction with the amounts drank by one person in a year (180 L/year), are high enough to warrant consideration by public health authorities and by people to whom high potassium intakes pose a risk. (author)

  1. Dual photon absorptiometer utilizing a HpGe detector and microprocessor controller

    International Nuclear Information System (INIS)

    Ellis, K.J.; Vartsky, D.; Pearlstein, T.B.; Alberi, J.L.; Cohn, S.H.

    1978-01-01

    The analysis of bone mineral content (BMC) using a single energy-photon beam assumes that there are only two materials present, bone mineral and a uniform soft tissue component. Uncertainty in the value of BMC increases with different adipose tissue components in the transmitted beam. These errors, however, are reduced by the dual energy technique. Also, extension to additional energies further identifies the separate constituents of the soft tissue component. A multi-energy bone scanning apparatus with data acquisition and analysis capability sufficient to perform multi-energy analysis of bone mineral content was designed and developed. The present work reports on the development of device operated in the dual energy mode. The high purity germanium (HpGe) detector is an integral component of the scanner. Errors in BMC due to multiple small angle scatters are reduced due to the excellent energy resolution of the detector (530 eV at 60 keV). Also, the need to filter the source or additional collimation on the detector is eliminated. A new dual source holder was designed using 200 mCi 125 I and 100 mCi 241 Am. The active areas of the two source capsules are aligned on a common axis. The congruence of the dual source was verified by measuring the collimator response function. This new holder design insures that the same tissue mass simultaneously attenuates both sources. The controller portion of the microprocessor allows for variation in total scan length, step size, and counting time per step. These options allow for multiple measurements without changes in the detector, source, or collimator. The system has been successfully used to determine the BMC content of different bones

  2. Development of fast measurements of concentration of NORM U-238 by HPGe

    Science.gov (United States)

    Cha, Seokki; Kim, Siu; Kim, Geehyun

    2017-02-01

    Naturally Occureed Radioactive Material (NORM) generated from the origin of earth can be found all around us and even people who are not engaged in the work related to radiation have been exposed to unnecessary radiation. This NORM has a potential risk provided that is concentrated or transformed by artificial activities. Likewise, a development of fast measruement method of NORM is emerging to prevent the radiation exposure of the general public and person engaged in the work related to the type of business related thereto who uses the material in which NORM is concentrated or transfromed. Based on such a background, many of countries have tried to manage NORM and carried out regulatory legislation. To effienctly manage NORM, there is need for developing new measurement to quickly and accurately analyze the nuclide and concentration. In this study, development of the fast and reliable measurement was carried out. In addition to confirming the reliability of the fast measurement, we have obtained results that can suggest the possibility of developing another fast measurement. Therefore, as a follow-up, it is possible to develop another fast analytical measurement afterwards. The results of this study will be very useful for the regulatory system to manage NORM. In this study, a review of two indirect measurement methods of NORM U-238 that has used HPGe on the basis of the equilibrium theory of relationships of mother and daughter nuclide at decay-chain of NORM U-238 has been carried out. For comparative study(in order to know reliabily), direct measurement that makes use of alpha spectrometer with complicated pre-processing process was implemented.

  3. X-ray fluorescence analysis in environmental radiological surveillance using HPGe detectors

    International Nuclear Information System (INIS)

    Herrera Peraza, E.; Renteria Villalobos, M.; Montero Cabrera, M.E.; Munoz Romero, A.

    2004-01-01

    X-ray fluorescence (XRF) has been proven to be a valuable tool for determining trace quantities of heavy metals, such as uranium and lead, in different types of samples. The present paper demonstrates the applicability of XRF spectrometry to measure the concentrations of these heavy metals in samples from natural ore and soil. The values of uranium concentrations in rock from the Pena Blanca uranium ore, in Chihuahua, Mexico, were calculated for the purpose of precertifying the rock powders samples. The comparison with other techniques, such as inductively coupled plasma atomic emission spectrometry, atomic absorption spectrometry, alpha spectrometry and electron microscopy, was used to complete the precertification process, so that the sample powders may be used as secondary standards. The source-sample-detector geometry and the incident angle are the most important factors for obtaining low detection limits. The selected system uses a 57 Co source of about 0.1 mCi to excite the K X-rays from uranium and lead. X-rays were recorded on a CANBERRA HPGe coaxial detector. The comparative results for two incident angles (90 deg and 180 deg ) performed previously by other authors show that the best geometry is the backscattering geometry. In the present paper, using EGS4 code system with Monte Carlo simulation, it was possible to determine the location and distribution of background produced by the Compton edge in the optimized geometry. This procedure allowed to find the minimum detectable concentration of uranium and lead, which was experimentally calculated using standards. The possibility of performing in vivo measurements rapidly and easily, as well as the factors affecting accuracy and the minimum detectable concentration in several samples are also discussed

  4. X-ray fluorescence analysis in environmental radiological surveillance using HPGe detectors

    Energy Technology Data Exchange (ETDEWEB)

    Herrera Peraza, E. [Department of Environmental Radiological Surveillance, Centro de Investigacion en Materiales Avanzados (CIMAV), P.O. Box 31109, Miguel de Cervantes no. 120, Complejo Industrial Chihuahua, Chihuahua (Mexico)]. E-mail: eduardo.herrera@cimav.edu.mx; Renteria Villalobos, M. [Department of Environmental Radiological Surveillance, Centro de Investigacion en Materiales Avanzados (CIMAV), P.O. Box 31109, Miguel de Cervantes no. 120, Complejo Industrial Chihuahua, Chihuahua (Mexico); Montero Cabrera, M.E. [Department of Environmental Radiological Surveillance, Centro de Investigacion en Materiales Avanzados (CIMAV), P.O. Box 31109, Miguel de Cervantes no. 120, Complejo Industrial Chihuahua, Chihuahua (Mexico); Munoz Romero, A. [Department of Environmental Radiological Surveillance, Centro de Investigacion en Materiales Avanzados (CIMAV), P.O. Box 31109, Miguel de Cervantes no. 120, Complejo Industrial Chihuahua, Chihuahua (Mexico)

    2004-10-08

    X-ray fluorescence (XRF) has been proven to be a valuable tool for determining trace quantities of heavy metals, such as uranium and lead, in different types of samples. The present paper demonstrates the applicability of XRF spectrometry to measure the concentrations of these heavy metals in samples from natural ore and soil. The values of uranium concentrations in rock from the Pena Blanca uranium ore, in Chihuahua, Mexico, were calculated for the purpose of precertifying the rock powders samples. The comparison with other techniques, such as inductively coupled plasma atomic emission spectrometry, atomic absorption spectrometry, alpha spectrometry and electron microscopy, was used to complete the precertification process, so that the sample powders may be used as secondary standards. The source-sample-detector geometry and the incident angle are the most important factors for obtaining low detection limits. The selected system uses a {sup 57}Co source of about 0.1 mCi to excite the K X-rays from uranium and lead. X-rays were recorded on a CANBERRA HPGe coaxial detector. The comparative results for two incident angles (90 deg and 180 deg ) performed previously by other authors show that the best geometry is the backscattering geometry. In the present paper, using EGS4 code system with Monte Carlo simulation, it was possible to determine the location and distribution of background produced by the Compton edge in the optimized geometry. This procedure allowed to find the minimum detectable concentration of uranium and lead, which was experimentally calculated using standards. The possibility of performing in vivo measurements rapidly and easily, as well as the factors affecting accuracy and the minimum detectable concentration in several samples are also discussed.

  5. Successful Large-volume Leukapheresis for Hematopoietic Stem Cell Collection in a Very-low-weight Brain Tumor Infant with Coagulopathy

    Directory of Open Access Journals (Sweden)

    Yu-Mei Liao

    2013-06-01

    Full Text Available Peripheral apheresis has become a safe procedure to collect hematopoietic stem cells, even in pediatric patients and donors. However, the apheresis procedure for small and sick children is more complicated due to difficult venous access, relatively large extracorporeal volume, toxicity of citrate, and unstable hemostasis. We report a small and sick child with refractory medulloblastoma, impaired liver function, and coagulopathy after several major cycles of cisplatin-based chemotherapy. She successfully received large-volume leukapheresis for hematopoietic stem cell collection, although the patient experienced severe coagulopathy during the procedures. Health care providers should be alert to this potential risk.

  6. Material inhomogeneities in Cd1-xZnxTe and their effects on large volume gamma-ray detectors

    International Nuclear Information System (INIS)

    Scyoc, J.M. Van; Lund, J.C.; Morse, D.H.

    1997-01-01

    Cadmium zinc telluride (Cd 1-x Zn x Te or CZT) has shown great promise as a material for room-temperature x-ray and gamma-ray detectors. In particular, polycrystalline material grown by the High Pressure Bridgman method with nominal Zn fraction (x) from 0.1 to 0.2 has been used to fabricate high resolution gamma-ray spectrometers with resolution approaching that of cooled high-purity Ge. For increased sensitivity, large areas (> 1 cm 2 ) are required, and for good sensitivity to high energy gamma photons, thick detectors (on the order of 1 cm) are required. Thus there has been a push for the development of CZT detectors with a volume greater than 1 cm 3 . However, nonuniformities in the material over this scale degrade the performance of the detectors. Variations in the zinc fraction, and thus the bandgap, and changes in the impurity distributions, both of which arise from the selective segregation of elements during crystal growth, result in spectral distortions. In this work several materials characterization techniques were combined with detector evaluations to determine the materials properties limiting detector performance. Materials measurements were performed on detectors found to have differing performance. Measurements conducted include infrared transmission (IR), particle induced x-ray emission (PIXE), photoluminescence (PL), and triaxial x-ray diffraction (TAXRD). To varying degrees, these measurements reveal that poor-performance detectors exhibit higher nonuniformities than spectrometer-grade detectors. This is reasonable, as regions of CZT material with different properties will give different localized spectral responses, which combine to result in a degraded spectrum for the total device

  7. Rain Characteristics and Large-Scale Environments of Precipitation Objects with Extreme Rain Volumes from TRMM Observations

    Science.gov (United States)

    Zhou, Yaping; Lau, William K M.; Liu, Chuntao

    2013-01-01

    This study adopts a "precipitation object" approach by using 14 years of Tropical Rainfall Measuring Mission (TRMM) Precipitation Feature (PF) and National Centers for Environmental Prediction (NCEP) reanalysis data to study rainfall structure and environmental factors associated with extreme heavy rain events. Characteristics of instantaneous extreme volumetric PFs are examined and compared to those of intermediate and small systems. It is found that instantaneous PFs exhibit a much wider scale range compared to the daily gridded precipitation accumulation range. The top 1% of the rainiest PFs contribute over 55% of total rainfall and have 2 orders of rain volume magnitude greater than those of the median PFs. We find a threshold near the top 10% beyond which the PFs grow exponentially into larger, deeper, and colder rain systems. NCEP reanalyses show that midlevel relative humidity and total precipitable water increase steadily with increasingly larger PFs, along with a rapid increase of 500 hPa upward vertical velocity beyond the top 10%. This provides the necessary moisture convergence to amplify and sustain the extreme events. The rapid increase in vertical motion is associated with the release of convective available potential energy (CAPE) in mature systems, as is evident in the increase in CAPE of PFs up to 10% and the subsequent dropoff. The study illustrates distinct stages in the development of an extreme rainfall event including: (1) a systematic buildup in large-scale temperature and moisture, (2) a rapid change in rain structure, (3) explosive growth of the PF size, and (4) a release of CAPE before the demise of the event.

  8. Large wood recruitment processes and transported volumes in Swiss mountain streams during the extreme flood of August 2005

    Science.gov (United States)

    Steeb, Nicolas; Rickenmann, Dieter; Badoux, Alexandre; Rickli, Christian; Waldner, Peter

    2017-02-01

    The extreme flood event that occurred in August 2005 was the most costly (documented) natural hazard event in the history of Switzerland. The flood was accompanied by the mobilization of > 69,000 m3 of large wood (LW) throughout the affected area. As recognized afterward, wood played an important role in exacerbating the damages, mainly because of log jams at bridges and weirs. The present study aimed at assessing the risk posed by wood in various catchments by investigating the amount and spatial variability of recruited and transported LW. Data regarding LW quantities were obtained by field surveys, remote sensing techniques (LiDAR), and GIS analysis and was subsequently translated into a conceptual model of wood transport mass balance. Detailed wood budgets and transport diagrams were established for four study catchments of Swiss mountain streams, showing the spatial variability of LW recruitment and deposition. Despite some uncertainties with regard to parameter assumptions, the sum of reconstructed wood input and observed deposition volumes agree reasonably well. Mass wasting such as landslides and debris flows were the dominant recruitment processes in headwater streams. In contrast, LW recruitment from lateral bank erosion became significant in the lower part of mountain streams where the catchment reached a size of about 100 km2. According to our analysis, 88% of the reconstructed total wood input was fresh, i.e., coming from living trees that were recruited from adjacent areas during the event. This implies an average deadwood contribution of 12%, most of which was estimated to have been in-channel deadwood entrained during the flood event.

  9. Research on volume metrology method of large vertical energy storage tank based on internal electro-optical distance-ranging method

    Science.gov (United States)

    Hao, Huadong; Shi, Haolei; Yi, Pengju; Liu, Ying; Li, Cunjun; Li, Shuguang

    2018-01-01

    A Volume Metrology method based on Internal Electro-optical Distance-ranging method is established for large vertical energy storage tank. After analyzing the vertical tank volume calculation mathematical model, the key processing algorithms, such as gross error elimination, filtering, streamline, and radius calculation are studied for the point cloud data. The corresponding volume values are automatically calculated in the different liquids by calculating the cross-sectional area along the horizontal direction and integrating from vertical direction. To design the comparison system, a vertical tank which the nominal capacity is 20,000 m3 is selected as the research object, and there are shown that the method has good repeatability and reproducibility. Through using the conventional capacity measurement method as reference, the relative deviation of calculated volume is less than 0.1%, meeting the measurement requirements. And the feasibility and effectiveness are demonstrated.

  10. A State-of-the-Art Report on Technologies of Volume Reduction and Self-Disposal for Large Metal Wastes including the Steam Generator of Nuclear Power Plants

    International Nuclear Information System (INIS)

    Lee, Kune Woo; Choi, W. K.; Kim, G. Y.

    2009-06-01

    This report focuses on technologies of volume reduction and self-disposal for large metal wastes including the steam generator of nuclear power plants. This report consists of the cases of treatments and foreign and domestic technologies for steam generator replacement

  11. Design of A HPGe-Plastic Scintillator Compton Suppression Spectrometer for Neutron Activation Analysis and Radio environmental Studies

    International Nuclear Information System (INIS)

    Sharshar, T.; Badran, H.; Elnimr, T.

    1998-01-01

    The design of a compton suppression spectrometer consisting of a 10% p-type HPGe detector and an annular anti-Compton shield made of N E-102 A plastic scintillator is described. The height of the guard plastic- scintillation detector was optimized experimentally using a NaI(Ti) ring, consisting of five NaI(Ti) detectors. The annular guard detector is divided to four optically isolated quarters to enhance the light collection. Each quarter of the guard detector was tested and satisfying results are obtained

  12. Effects of large volume injection of aliphatic alcohols as sample diluents on the retention of low hydrophobic solutes in reversed-phase liquid chromatography.

    Science.gov (United States)

    David, Victor; Galaon, Toma; Aboul-Enein, Hassan Y

    2014-01-03

    Recent studies showed that injection of large volume of hydrophobic solvents used as sample diluents could be applied in reversed-phase liquid chromatography (RP-LC). This study reports a systematic research focused on the influence of a series of aliphatic alcohols (from methanol to 1-octanol) on the retention process in RP-LC, when large volumes of sample are injected on the column. Several model analytes with low hydrophobic character were studied by RP-LC process, for mobile phases containing methanol or acetonitrile as organic modifiers in different proportions with aqueous component. It was found that starting with 1-butanol, the aliphatic alcohols can be used as sample solvents and they can be injected in high volumes, but they may influence the retention factor and peak shape of the dissolved solutes. The dependence of the retention factor of the studied analytes on the injection volume of these alcohols is linear, with a decrease of its value as the sample volume is increased. The retention process in case of injecting up to 200μL of upper alcohols is dependent also on the content of the organic modifier (methanol or acetonitrile) in mobile phase. Copyright © 2013 Elsevier B.V. All rights reserved.

  13. A new adsorption-elution technique for the concentration of aquatic extracellular antibiotic resistance genes from large volumes of water.

    Science.gov (United States)

    Wang, Da-Ning; Liu, Lu; Qiu, Zhi-Gang; Shen, Zhi-Qiang; Guo, Xuan; Yang, Dong; Li, Jing; Liu, Wei-Li; Jin, Min; Li, Jun-Wen

    2016-04-01

    Extracellular antibiotic resistance genes (eARGs) that help in the transmission and spread of antibiotic-resistant bacteria are emerging environmental contaminants in water, and there is therefore a growing need to assess environmental levels and associated risks of eARGs. However, as they are present in low amounts, it is difficult to detect eARGs in water directly with PCR techniques. Here, we prepared a new type of nucleic acid adsorption particle (NAAP) with high capacity and developed an optimal adsorption-elution method to concentrate eARGs from large volumes of water. With this technique, we were able to achieve an eARG recovery rate of above 95% from 10 L of water samples. Moreover, combining this new method with quantitative real-time PCR (qPCR), the sensitivity of the eARG detection was 10(4) times that of single qPCR, with the detection limit lowered to 100 gene copies (GCs)/L. Our analyses showed that the eARG load, virus load and certain water characteristics such as pH, chemical oxygen demand (CODMn), and turbidity affected the eARGs recovery rate. However, high eARGs recovery rates always remained within the standard limits for natural surface water quality, while eARG levels in water were lower than the detection limits of single qPCR assays. The recovery rates were not affected by water temperature and heterotrophic plate counts (HPC). The eARGs whatever located in the plasmids or the short-length linear DNAs can be recovered from the water. Furthermore, the recovery rate was high even in the presence of high concentrations of plasmids in different natural water (Haihe river, well water, raw water for drinking water, Jinhe river, Tuanbo lake and the Yunqiao reservoir). By this technology, eARGs concentrations were found ranging from (2.70 ± 0.73) × 10(2) to (4.58 ± 0.47) × 10(4) GCs/L for the extracellular ampicillin resistance gene and (5.43 ± 0.41) × 10(2) to (2.14 ± 0.23) × 10(4) GCs/L for the extracellular gentamicin

  14. In vitro validation of a Pitot-based flow meter for the measurement of respiratory volume and flow in large animal anaesthesia.

    Science.gov (United States)

    Moens, Yves P S; Gootjes, Peter; Ionita, Jean-Claude; Heinonen, Erkki; Schatzmann, Urs

    2009-05-01

    To remodel and validate commercially available monitors and their Pitot tube-based flow sensors for use in large animals, using in vitro techniques. Prospective, in vitro experiment. Both the original and the remodelled sensor were studied with a reference flow generator. Measurements were taken of the static flow-pressure relationship and linearity of the flow signal. Sensor airway resistance was calculated. Following recalibration of the host monitor, volumes ranging from 1 to 7 L were generated by a calibration syringe, and bias and precision of spirometric volume was determined. Where manual recalibration was not available, a conversion factor for volume measurement was determined. The influence of gas composition mixture and peak flow on the conversion factor was studied. Both the original and the remodelled sensor showed similar static flow-pressure relationships and linearity of the flow signal. Mean bias (%) of displayed values compared with the reference volume of 3, 5 and 7 L varied between -0.4% and +2.4%, and this was significantly smaller than that for 1 L (4.8% to +5.0%). Conversion factors for 3, 5 and 7 L were very similar (mean 6.00 +/- 0.2, range 5.91-6.06) and were not significantly influenced by the gas mixture used. Increasing peak flow caused a small decrease in the conversion factor. Volume measurement error and conversion factors for inspiration and expiration were close to identity. The combination of the host monitor with the remodelled flow sensor allowed accurate in vitro measurement of flows and volumes in a range expected during large animal anaesthesia. This combination has potential as a reliable spirometric monitor for use during large animal anaesthesia.

  15. Development of a technique for the efficiency calibration of a HPGe detector for the off gas samples of a nuclear reactor

    International Nuclear Information System (INIS)

    Singh, Sarbjit; Agarwal, Chhavi; Ramaswami, A.; Manchanda, V.K.

    2007-01-01

    Regular monitoring of off gases released to the environment from a nuclear reactor is mandatory. The gaseous fission products are estimated by gamma ray spectrometry using a HPGe detector coupled to a multichannel analyser. In view of the lack of availability of gaseous fission products standards, an indirect method based on the charcoal absorption technique was developed for the efficiency calibration of HPGe detector system using 133B a and 152E u standards. The known activities of 133B a and 152E u are uniformly distributed in a vial having activated charcoal and counted on the HPGe detector system at liquid nitrogen temperature to determine the gamma ray efficiency for the vial having activated charcoal. The ratio of the gamma ray efficiencies of off gas present in the normal vial and the vial having activated charcoal at liquid nitrogen temperature are used to determine the gamma ray efficiency of off gas present in the normal vial. (author)

  16. Ninth degree polynomial fit function for calculation of efficiency calibrations for Ge(Li) and HPGe detectors

    International Nuclear Information System (INIS)

    Uosif, M.A.M.

    2006-01-01

    A new 9 th degree polynomial fit function has been constructed to calculate the absolute γ-ray detection efficiencies (ηth) of Ge(Li) and HPGe Detectors, for calculating the absolute efficiency at any interesting γ-energy in the energy range between 25 and 2000 keV and distance between 6 and 148 cm. The total absolute γ -ray detection efficiencies have been calculated for six detectors, three of them are Ge(Li) and three HPGe at different distances. The absolute efficiency of the different detectors was calculated at the specific energy of the standard sources for each measuring distances. In this calculation, experimental (η e xp) and fitting (η f it) efficiency have been calculated. Seven calibrated point sources Am-241, Ba-133, Co-57, Co-60, Cs-137, Eu-152 and Ra-226 were used. The uncertainties of efficiency calibration have been calculated also for quality control. The measured (η e xp) and (η f it) calculated efficiency values were compared with efficiency, which calculated, by Gray fit function (time)- The results obtained on the basis of (η e xp)and (η f it) seem to be in very good agreement

  17. Determination of 137Cs and 210Pb using HPGe γ spectrometry as influenced by different sieve diameters

    International Nuclear Information System (INIS)

    Liu Yehan; Yu Hanqing; Geng Xiaochen; Li Yong

    2012-01-01

    Standard sieve diameter is often set as 2.00 mm to determine specific activity of 137 Cs and 210 Pb in soil samples, but it is rarely reported that whether the size of the different screening will affect the accuracy of such determination. In this study, three representative soils were employed to assess the effects of different sieve sizes on measurement of 137 Cs and 210 Pb activity in soil samples by using HPGe γ spectrometer. The targeted soil samples each were screened through the four sieve diameters 2.00, 1.00, 0.50 and 0.25 mm, respectively. It was observed that the sample of 0.25 mm took less time to reach the acceptable value of 137 Cs analysis precision and higher value of the specific activity in the three soils compared to the 2.00 mm sifting sample. As for 210 Pb measurement, the decrease of sieve diameters extended to touch the acceptable value of analysis precision but showed no significant effect on the specific activity. These results played an important role in enhancing the analysis precision of the specific activity of 137 Cs and 210 Pb in soil samples using HPGe γ Spectrometry. (authors)

  18. Monte Carlo Calculation Of HPGe GEM 15P4 Detector Efficiency In The 59 - 2000 keV Energy Range

    International Nuclear Information System (INIS)

    Trinh Hoai Vinh; Pham Nguyen Thanh Vinh; Hoang Ba Kim; Vo Xuan An

    2011-01-01

    A precise model of a 15% relative efficiency p-type HPGe GEM 15P4 detector was created for peak efficiency curves determination using the MCNP5 code developed by The Los Alamos Laboratory. The dependence of peak efficiency on distance from the source to detector was also investigated. That model was validated by comparing experimental and calculated results using six standard point sources including 133 Ba, 109 Cd, 57 Co, 60 Co, 22 Na and 65 Zn. The sources used for more simulating are 241 Am, 75 Se, 113 Sn, 85 Sr, 54 Mn, 137 Cs, 56 Co, 94 Nb, 111 In, 139 Ce, 228 Th, 243 Am, 154 Eu, 152 Eu and 88 Y according to IAEA-TECDOC-619 document. All these sources have the same geometry. The ratio of the experimental efficiencies to calculated ones are higher than 0.94. This result indicates that our simulation program based on MCNP5 code is good enough for later studies on this HPGe spectrometer which is located in Nuclear Physics Laboratory at HCMC University of Pedagogy. (author)

  19. Portable waveguide display system with a large field of view by integrating freeform elements and volume holograms.

    Science.gov (United States)

    Han, Jian; Liu, Juan; Yao, Xincheng; Wang, Yongtian

    2015-02-09

    A compact waveguide display system integrating freeform elements and volume holograms is presented here for the first time. The use of freeform elements can broaden the field of view, which limits the applications of a holographic waveguide. An optimized system can achieve a diagonal field of view of 45° when the thickness of the waveguide planar is 3mm. Freeform-elements in-coupler and the volume holograms out-coupler were designed in detail in our study, and the influence of grating configurations on diffraction efficiency was analyzed thoroughly. The off-axis aberrations were well compensated by the in-coupler and the diffraction efficiency of the optimized waveguide display system could reach 87.57%. With integrated design, stability and reliability of this monochromatic display system were achieved and the alignment of the system was easily controlled by the record of the volume holograms, which makes mass production possible.

  20. Deep-water gamma-spectrometer based on HP(Ge) detector

    International Nuclear Information System (INIS)

    Sokolov, A.; Danengirsh, S.; Popov, S.; Pchelincev, A; Gostilo, V.; Kravchenko, S.; Shapovalov, V.; Druzhinin, A.

    1995-01-01

    Full text: For radionuclide monitoring of the sea bottom near underwater storage of high active waste of nuclear industries and near places of accidents with nuclear submarines the spectrometers of gamma-radiation, which allow to carry out the measurements on the great depth, are needed. Usually, these problems are solved with devices, which are cast down into the water, using the rope, and transmit the signals on the surface by the cable. However, the depth of immersion is limited by this construction and often the conditions of measurement are complicated. The deep water gamma-spectrometer based on HP(Ge) detector for the measurement on the depth up to 3000 m is developed. The spectrometer is completely autonomic and is put up in the selected place, using the manipulator of a deep-water apparatus. The spectrometer is created in two cylindrical cases with 170 mm diameter and 1100 mm length, bearing the high hydrostatic pressure. The part of the case around the detector is created from titanium and has especial construction with a thin wall for increasing the efficiency of registration in the region of low-energy gamma-radiation. The cooling of the semiconductor detector is provided by a coolant which supports the working temperature of the detector during more than 24 hours. The electronic system of the spectrometer includes high voltage supply f or the detector, preamplifier, analog processor, analog-digital converter and a device for collecting and storing information in flash memory. The power supply of the spectrometer is provided by a battery of accumulators, which can be recharged on the surface. The programming of the processor is carried out before immersion by connecting the spectrometer to personal computer using standard interface RS-232. During 24 hours the spectrometer provides registration of 16 spectrums each in 4096 channels. The reading of the information by the computer is carried out after lifting up the spectrometer on the surface in the same

  1. Simulation and real-time analysis of pulse shapes from segmented HPGe-detectors

    Energy Technology Data Exchange (ETDEWEB)

    Schlarb, Michael Christian

    2009-11-17

    The capabilities of future HPGe arrays consisting of highly segmented detectors, like AGATA will depend heavily on the performance of {gamma}-ray tracking. The most crucial component in the whole concept is the pulse shape analysis (PSA). The working principle of PSA is to compare the experimental signal shape with signals available from a basis set with known interaction locations. The efficiency of the tracking algorithm hinges on the ability of the PSA to reconstruct the interaction locations accurately, especially for multiple {gamma}-interactions. Given the size of the arrays the PSA algorithm must be run in a real-time environment. A prerequisite to a successful PSA is an accurate knowledge of the detectors response. Making a full coincidence scan of a single AGATA detector, however takes between two and three months, which is too long to produce an experimental signal basis for all detector elements. A straight forward possibility is to use a precise simulation of the detector and to provide a basis of simulated signals. For this purpose the Java Agata Signal Simulation (JASS) was developed in the course of this thesis. The geometry of the detector is given with numerical precision and models describing the anisotropic mobilities of the charge carriers in germanium were taken from the literature. The pulse shapes of the transient and net-charge signals are calculated using weighting potentials on a finite grid. Special care was taken that the interpolation routine not only reproduces the weighting potentials precisely in the highly varying areas of the segment boundaries but also that its performance is independent of the location within the detector. Finally data from a coincidence scan and a pencil beam experiment were used to verify JASS. The experimental signals are reproduced accurately by the simulation. Pulse Shape Analysis (PSA) reconstructs the positions of the individual interactions and the corresponding energy deposits within the detector. This

  2. Simulation and real-time analysis of pulse shapes from segmented HPGe-detectors

    International Nuclear Information System (INIS)

    Schlarb, Michael Christian

    2009-01-01

    The capabilities of future HPGe arrays consisting of highly segmented detectors, like AGATA will depend heavily on the performance of γ-ray tracking. The most crucial component in the whole concept is the pulse shape analysis (PSA). The working principle of PSA is to compare the experimental signal shape with signals available from a basis set with known interaction locations. The efficiency of the tracking algorithm hinges on the ability of the PSA to reconstruct the interaction locations accurately, especially for multiple γ-interactions. Given the size of the arrays the PSA algorithm must be run in a real-time environment. A prerequisite to a successful PSA is an accurate knowledge of the detectors response. Making a full coincidence scan of a single AGATA detector, however takes between two and three months, which is too long to produce an experimental signal basis for all detector elements. A straight forward possibility is to use a precise simulation of the detector and to provide a basis of simulated signals. For this purpose the Java Agata Signal Simulation (JASS) was developed in the course of this thesis. The geometry of the detector is given with numerical precision and models describing the anisotropic mobilities of the charge carriers in germanium were taken from the literature. The pulse shapes of the transient and net-charge signals are calculated using weighting potentials on a finite grid. Special care was taken that the interpolation routine not only reproduces the weighting potentials precisely in the highly varying areas of the segment boundaries but also that its performance is independent of the location within the detector. Finally data from a coincidence scan and a pencil beam experiment were used to verify JASS. The experimental signals are reproduced accurately by the simulation. Pulse Shape Analysis (PSA) reconstructs the positions of the individual interactions and the corresponding energy deposits within the detector. This is

  3. Theoretical determination of spectrum-exposure rate conversion operator of HPGe detector and its application to the measurement of environmental gamma-ray exposure rate

    International Nuclear Information System (INIS)

    Park, Ch.M.; Choi, B.I.; Kwak, S.S.; Ji, P.K.; Kim, T.W.; Park, Y.W.; Yoon, B.K.

    1993-01-01

    A conversion operator between spectrum and exposure rate, using a portable HPGe detector for environmental radiation monitoring, was determined theoretically under the assumption of uniform distribution of radiation source on the ground surface. The measurement results were compared with those of a pressurized ionization chamber. The results obtained with the HPGe detector were slightly lower. The method can be easily applied to any gamma ray detector to obtain a spectrum - exposure-rate conversion factor for computing the exposure rate of environmental gamma radiation. (N.T.) 15 refs.; 6 figs.; 3 tabs

  4. System of large transport containers for waste from dismantling light water and gas-cooled nuclear reactors. Volume 1

    International Nuclear Information System (INIS)

    Price, M.S.T.; Lafontaine, I.

    1985-01-01

    The purpose of this volume is to introduce the main types of nuclear reactor in the European Community (EC), select reference plants for further study, estimate the waste streams from the reference reactors, survey the transport regulations and assess existing containers

  5. Solid phase extraction of large volume of water and beverage samples to improve detection limits for GC-MS analysis of bisphenol A and four other bisphenols.

    Science.gov (United States)

    Cao, Xu-Liang; Popovic, Svetlana

    2018-01-01

    Solid phase extraction (SPE) of large volumes of water and beverage products was investigated for the GC-MS analysis of bisphenol A (BPA), bisphenol AF (BPAF), bisphenol F (BPF), bisphenol E (BPE), and bisphenol B (BPB). While absolute recoveries of the method were improved for water and some beverage products (e.g. diet cola, iced tea), breakthrough may also have occurred during SPE of 200 mL of other beverages (e.g. BPF in cola). Improvements in method detection limits were observed with the analysis of large sample volumes for all bisphenols at ppt (pg/g) to sub-ppt levels. This improvement was found to be proportional to sample volumes for water and beverage products with less interferences and noise levels around the analytes. Matrix effects and interferences were observed during SPE of larger volumes (100 and 200 mL) of the beverage products, and affected the accurate analysis of BPF. This improved method was used to analyse bisphenols in various beverage samples, and only BPA was detected, with levels ranging from 0.022 to 0.030 ng/g for products in PET bottles, and 0.085 to 0.32 ng/g for products in cans.

  6. New methods to interpolate large volume of data from points or particles (Mesh-Free) methods application for its scientific visualization

    International Nuclear Information System (INIS)

    Reyes Lopez, Y.; Yervilla Herrera, H.; Viamontes Esquivel, A.; Recarey Morfa, C. A.

    2009-01-01

    In the following paper we developed a new method to interpolate large volumes of scattered data, focused mainly on the results of the Mesh free Methods, Points Methods and the Particles Methods application. Through this one, we use local radial basis function as interpolating functions. We also use over-tree as the data structure that allows to accelerate the localization of the data that influences to interpolate the values at a new point, speeding up the application of scientific visualization techniques to generate images from large data volumes from the application of Mesh-free Methods, Points and Particle Methods, in the resolution of diverse models of physics-mathematics. As an example, the results obtained after applying this method using the local interpolation functions of Shepard are shown. (Author) 22 refs

  7. CREPT-MCNP code for efficiency calibration of HPGe detectors with the representative point method.

    Science.gov (United States)

    Saegusa, Jun

    2008-01-01

    The representative point method for the efficiency calibration of volume samples has been previously proposed. For smoothly implementing the method, a calculation code named CREPT-MCNP has been developed. The code estimates the position of a representative point which is intrinsic to each shape of volume sample. The self-absorption correction factors are also given to make correction on the efficiencies measured at the representative point with a standard point source. Features of the CREPT-MCNP code are presented.

  8. Quantifying the Impact of Immediate Reconstruction in Postmastectomy Radiation: A Large, Dose-Volume Histogram-Based Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Ohri, Nisha [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Cordeiro, Peter G. [Department of Plastic Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Keam, Jennifer [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Ballangrud, Ase [Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Shi Weiji; Zhang Zhigang [Department of Biostatistics and Epidemiology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Nerbun, Claire T.; Woch, Katherine M.; Stein, Nicholas F.; Zhou Ying [Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); McCormick, Beryl; Powell, Simon N. [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Ho, Alice Y., E-mail: HoA1234@mskcc.org [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States)

    2012-10-01

    Purpose: To assess the impact of immediate breast reconstruction on postmastectomy radiation (PMRT) using dose-volume histogram (DVH) data. Methods and Materials: Two hundred forty-seven women underwent PMRT at our center, 196 with implant reconstruction and 51 without reconstruction. Patients with reconstruction were treated with tangential photons, and patients without reconstruction were treated with en-face electron fields and customized bolus. Twenty percent of patients received internal mammary node (IMN) treatment. The DVH data were compared between groups. Ipsilateral lung parameters included V20 (% volume receiving 20 Gy), V40 (% volume receiving 40 Gy), mean dose, and maximum dose. Heart parameters included V25 (% volume receiving 25 Gy), mean dose, and maximum dose. IMN coverage was assessed when applicable. Chest wall coverage was assessed in patients with reconstruction. Propensity-matched analysis adjusted for potential confounders of laterality and IMN treatment. Results: Reconstruction was associated with lower lung V20, mean dose, and maximum dose compared with no reconstruction (all P<.0001). These associations persisted on propensity-matched analysis (all P<.0001). Heart doses were similar between groups (P=NS). Ninety percent of patients with reconstruction had excellent chest wall coverage (D95 >98%). IMN coverage was superior in patients with reconstruction (D95 >92.0 vs 75.7%, P<.001). IMN treatment significantly increased lung and heart parameters in patients with reconstruction (all P<.05) but minimally affected those without reconstruction (all P>.05). Among IMN-treated patients, only lower lung V20 in those without reconstruction persisted (P=.022), and mean and maximum heart doses were higher than in patients without reconstruction (P=.006, P=.015, respectively). Conclusions: Implant reconstruction does not compromise the technical quality of PMRT when the IMNs are untreated. Treatment technique, not reconstruction, is the primary

  9. Calibration efficiency of HPGe detector in the 50-1800 KeV energy range; Calibracao em eficiencia de um detector HPGe na faixa de energias 50 - 1800KeV

    Energy Technology Data Exchange (ETDEWEB)

    Venturini, Luzia [Instituto de Pesquisas Energeticas e Nucleares (IPEN), Sao Paulo, SP (Brazil). Servico de Monitoracao Ambiental

    1996-07-01

    This paper describes the efficiency of an HPGe detector in the 50 - 1800 keV energy range, for two geometries for water measurements: Marinelli breaker (850 ml) and a polyethylene flask (100 ml). The experimental data were corrected for the summing effect and fitted to a continuous, differentiable and energy dependent function given by 1n({epsilon})=b{sub 0}+b{sub 1}.1n(E/E{sub 0})+ {beta}.1n(E/E{sub 0}){sup 2}, where {beta} = b{sub 2} if E>E{sub 0} and {beta} =a{sub 2} if E {<=}E{sub 0}; {epsilon} = the full absorption peak efficiency; E is the gamma-ray energy and {l_brace}b{sub 0}, b{sub 1}, b{sub 2}, a{sub 2}, E{sub 0} {r_brace} is the parameter set to be fitted. (author)

  10. Large volume TENAX {sup registered} extraction of the bioaccessible fraction of sediment-associated organic compounds for a subsequent effect-directed analysis

    Energy Technology Data Exchange (ETDEWEB)

    Schwab, K.; Brack, W. [UFZ - Helmholtz Centre or Environmental Research, Leipzig (Germany). Dept. of Effect-Directed Analysis

    2007-06-15

    Background, Aim and Scope: Effect-directed analysis (EDA) is a powerful tool for the identification of key toxicants in complex environmental samples. In most cases, EDA is based on total extraction of organic contaminants leading to an erroneous prioritization with regard to hazard and risk. Bioaccessibility-directed extraction aims to discriminate between contaminants that take part in partitioning between sediment and biota in a relevant time frame and those that are enclosed in structures, that do not allow rapid desorption. Standard protocols of targeted extraction of rapidly desorbing, and thus bioaccessible fraction using TENAX {sup registered} are based only on small amounts of sediment. In order to get sufficient amounts of extracts for subsequent biotesting, fractionation, and structure elucidation a large volume extraction technique needs to be developed applying one selected extraction time and excluding toxic procedural blanks. Materials and Methods: Desorption behaviour of sediment contaminants was determined by a consecutive solid-solid extraction of sediment using TENAX {sup registered} fitting a tri-compartment model on experimental data. Time needed to remove the rapidly desorbing fraction trap was calculated to select a fixed extraction time for single extraction procedures. Up-scaling by about a factor of 100 provided a large volume extraction technique for EDA. Reproducibility and comparability to small volume approach were proved. Blanks of respective TENAX {sup registered} mass were investigated using Scenedesmus vacuolatus and Artemia salina as test organisms. Results: Desorption kinetics showed that 12 to 30 % of sediment associated pollutants are available for rapid desorption. t{sub r}ap is compound dependent and covers a range of 2 to 18 h. On that basis a fixed extraction time of 24 h was selected. Validation of large volume approach was done by the means of comparison to small method and reproducibility. The large volume showed a good

  11. Low volume, large force (>1mN) and nanometer resolution, electrostatic microactuator for low displacement applications

    NARCIS (Netherlands)

    Sarajlic, Edin; Berenschot, Johan W.; Krijnen, Gijsbertus J.M.; Elwenspoek, Michael Curt

    2003-01-01

    A compact electrostatic microactuator suitable for low displacement applications is proposed. The actuator employs a large number of basic units working in parallel together with a built-in mechanical transformation to generate large force. Influence of distinct design parameters on actuator

  12. Large-volume injection of sample diluents not miscible with the mobile phase as an alternative approach in sample preparation for bioanalysis: an application for fenspiride bioequivalence.

    Science.gov (United States)

    Medvedovici, Andrei; Udrescu, Stefan; Albu, Florin; Tache, Florentin; David, Victor

    2011-09-01

    Liquid-liquid extraction of target compounds from biological matrices followed by the injection of a large volume from the organic layer into the chromatographic column operated under reversed-phase (RP) conditions would successfully combine the selectivity and the straightforward character of the procedure in order to enhance sensitivity, compared with the usual approach of involving solvent evaporation and residue re-dissolution. Large-volume injection of samples in diluents that are not miscible with the mobile phase was recently introduced in chromatographic practice. The risk of random errors produced during the manipulation of samples is also substantially reduced. A bioanalytical method designed for the bioequivalence of fenspiride containing pharmaceutical formulations was based on a sample preparation procedure involving extraction of the target analyte and the internal standard (trimetazidine) from alkalinized plasma samples in 1-octanol. A volume of 75 µl from the octanol layer was directly injected on a Zorbax SB C18 Rapid Resolution, 50 mm length × 4.6 mm internal diameter × 1.8 µm particle size column, with the RP separation being carried out under gradient elution conditions. Detection was made through positive ESI and MS/MS. Aspects related to method development and validation are discussed. The bioanalytical method was successfully applied to assess bioequivalence of a modified release pharmaceutical formulation containing 80 mg fenspiride hydrochloride during two different studies carried out as single-dose administration under fasting and fed conditions (four arms), and multiple doses administration, respectively. The quality attributes assigned to the bioanalytical method, as resulting from its application to the bioequivalence studies, are highlighted and fully demonstrate that sample preparation based on large-volume injection of immiscible diluents has an increased potential for application in bioanalysis.

  13. Containment at the Source during Waste Volume Reduction of Large Radioactive Components Using Oxylance High-Temperature Cutting Equipment - 13595

    International Nuclear Information System (INIS)

    Keeney, G. Neil

    2013-01-01

    As a waste-volume reduction and management technique, highly contaminated Control Element Drive Mechanism (CEDM) housings were severed from the Reactor Pressure Vessel Head (RPVH) inside the San Onofre Unit 2 primary containment utilizing Oxylance high-temperature cutting equipment and techniques. Presented are relevant data concerning: - Radiological profiles of the RPVH and individual CEDMs; - Design overviews of the engineering controls and the specialized confinement housings; - Utilization of specialized shielding; - Observations of apparent metallurgical-contamination coalescence phenomena at high temperatures resulting in positive control over loose-surface contamination conditions; - General results of radiological and industrial hygiene air sampling and monitoring; - Collective dose and personnel contamination event statistics; - Lessons learned. (author)

  14. Containment at the Source during Waste Volume Reduction of Large Radioactive Components Using Oxylance High-Temperature Cutting Equipment - 13595

    Energy Technology Data Exchange (ETDEWEB)

    Keeney, G. Neil [Health Physicist, HazMat CATS, LLC (United States)

    2013-07-01

    As a waste-volume reduction and management technique, highly contaminated Control Element Drive Mechanism (CEDM) housings were severed from the Reactor Pressure Vessel Head (RPVH) inside the San Onofre Unit 2 primary containment utilizing Oxylance high-temperature cutting equipment and techniques. Presented are relevant data concerning: - Radiological profiles of the RPVH and individual CEDMs; - Design overviews of the engineering controls and the specialized confinement housings; - Utilization of specialized shielding; - Observations of apparent metallurgical-contamination coalescence phenomena at high temperatures resulting in positive control over loose-surface contamination conditions; - General results of radiological and industrial hygiene air sampling and monitoring; - Collective dose and personnel contamination event statistics; - Lessons learned. (author)

  15. Efficiency calibration of x-ray HPGe detectors for photons with energies above the Ge K binding energy

    Energy Technology Data Exchange (ETDEWEB)

    Maidana, Nora L., E-mail: nmaidana@if.usp.br [Instituto de Física, Universidade de São Paulo, Travessa R 187, Cidade Universitária, CEP:05508-900 São Paulo, SP (Brazil); Vanin, Vito R.; Jahnke, Viktor [Instituto de Física, Universidade de São Paulo, Travessa R 187, Cidade Universitária, CEP:05508-900 São Paulo, SP (Brazil); Fernández-Varea, José M. [Facultat de Física (ECM and ICC), Universitat de Barcelona, Diagonal 645, E-08028 Barcelona (Spain); Martins, Marcos N. [Instituto de Física, Universidade de São Paulo, Travessa R 187, Cidade Universitária, CEP:05508-900 São Paulo, SP (Brazil); Brualla, Lorenzo [NCTeam, Strahlenklinik, Universitätsklinikum Essen, Hufelandstraße 55, D-45122 Essen (Germany)

    2013-11-21

    We report on the efficiency calibration of a HPGe x-ray detector using radioactive sources and an analytical expression taken from the literature, in two different arrangements, with and without a broad-angle collimator. The frontal surface of the Ge crystal was scanned with pencil beams of photons. The Ge dead layer was found to be nonuniform, with central and intermediate regions that have thin (μm range) and thick (mm range) dead layers, respectively, surrounded by an insensitive ring. We discuss how this fact explains the observed efficiency curves and generalize the adopted model. We show that changes in the thickness of the Ge-crystal dead layer affect the efficiency of x-ray detectors, but the use of an appropriate broad-beam external collimator limiting the photon flux to the thin dead layer in the central region leads to the expected efficiency dependence with energy and renders the calibration simpler.

  16. Simulated minimum detectable activity concentration (MDAC) for a real-time UAV airborne radioactivity monitoring system with HPGe and LaBr_3 detectors

    International Nuclear Information System (INIS)

    Tang, Xiao-Bin; Meng, Jia; Wang, Peng; Cao, Ye; Huang, Xi; Wen, Liang-Sheng; Chen, Da

    2016-01-01

    An automatic real-time UAV airborne radioactivity monitoring system with high-purity germanium (HPGe) and lanthanum bromide (LaBr_3) detectors (NH-UAV) was developed to precisely obtain small-scope nuclide information in major nuclear accidents. The specific minimum detectable activity concentration (MDAC) calculation method for NH-UAV in the atmospheric environment was deduced in this study for a priori evaluation and quantification of the suitability of NH-UAV in the Fukushima nuclear accident, where the MDAC values of this new equipment were calculated based on Monte Carlo simulation. The effects of radioactive source term size and activity concentration on the MDAC values were analyzed to assess the detection performance of NH-UAV in more realistic environments. Finally, the MDAC values were calculated at different shielding thicknesses of the HPGe detector to improve the detection capabilities of the HPGe detector, and the relationship between the MDAC and the acquisition time of the system was deduced. The MDAC calculation method and data results in this study may be used as a reference for in-situ radioactivity measurement of NH-UAV. - Highlights: • A real-time UAV airborne radioactivity monitoring system (NH-UAV) was developed. • The efficiency calculations and MDAC values are given. • NH-UAV is able to monitor major nuclear accidents, such as the Fukushima accident. • The source term size can influence the detection sensitivity of the system. • The HPGe detector possesses measurement thresholds on activity concentration.

  17. Validation of an efficiency calibration procedure for a coaxial n-type and a well-type HPGe detector used for the measurement of environmental radioactivity

    Energy Technology Data Exchange (ETDEWEB)

    Morera-Gómez, Yasser, E-mail: ymore24@gamail.com [Centro de Estudios Ambientales de Cienfuegos, AP 5. Ciudad Nuclear, CP 59350 Cienfuegos (Cuba); Departamento de Química y Edafología, Universidad de Navarra, Irunlarrea No 1, Pamplona 31009, Navarra (Spain); Cartas-Aguila, Héctor A.; Alonso-Hernández, Carlos M.; Nuñez-Duartes, Carlos [Centro de Estudios Ambientales de Cienfuegos, AP 5. Ciudad Nuclear, CP 59350 Cienfuegos (Cuba)

    2016-05-11

    To obtain reliable measurements of the environmental radionuclide activity using HPGe (High Purity Germanium) detectors, the knowledge of the absolute peak efficiency is required. This work presents a practical procedure for efficiency calibration of a coaxial n-type and a well-type HPGe detector using experimental and Monte Carlo simulations methods. The method was performed in an energy range from 40 to 1460 keV and it can be used for both, solid and liquid environmental samples. The calibration was initially verified measuring several reference materials provided by the IAEA (International Atomic Energy Agency). Finally, through the participation in two Proficiency Tests organized by IAEA for the members of the ALMERA network (Analytical Laboratories for the Measurement of Environmental Radioactivity) the validity of the developed procedure was confirmed. The validation also showed that measurement of {sup 226}Ra should be conducted using coaxial n-type HPGe detector in order to minimize the true coincidence summing effect. - Highlights: • An efficiency calibration for a coaxial and a well-type HPGe detector was performed. • The calibration was made using experimental and Monte Carlo simulations methods. • The procedure was verified measuring several reference materials provided by IAEA. • Calibrations were validated through the participation in 2 ALMERA Proficiency Tests.

  18. Large-Animal Biventricular Working Heart Perfusion System with Low Priming Volume-Comparison between in vivo and ex vivo Cardiac Function.

    Science.gov (United States)

    Abicht, Jan-Michael; Mayr, Tanja Axinja Jelena; Jauch, Judith; Guethoff, Sonja; Buchholz, Stefan; Reichart, Bruno; Bauer, Andreas

    2018-01-01

    Existing large-animal, ex vivo, cardiac perfusion models are restricted in their ability to establish an ischemia/reperfusion condition as seen in cardiac surgery or transplantation. Other working heart systems only challenge one ventricle or require a substantially larger priming volume. We describe a novel biventricular cardiac perfusion system with reduced priming volume. Juvenile pig hearts were cardiopleged, explanted, and reperfused ex vivo after 150 minutes of cold ischemia. Autologous whole blood was used as perfusate (minimal priming volume 350 mL). After 15 minutes of Langendorff perfusion (LM), the system was switched into a biventricular working mode (WM) and studied for 3 hours. During reperfusion, complete unloading of both ventricles and constant-pressure coronary perfusion was achieved. During working mode perfusion, the preload and afterload pressure of both ventricles was controlled within the targeted physiologic range. Functional parameters such as left ventricular work index were reduced in ex vivo working mode (in vivo: 787 ± 186 vs. 1 h WM 498 ± 66 mm Hg·mL/g·min; p  hours while functional and blood parameters are easily accessible. Moreover, because of the minimal priming volume, the novel ex vivo cardiac perfusion circuit allows for autologous perfusion, using the limited amount of blood available from the organ donating animal. Georg Thieme Verlag KG Stuttgart · New York.

  19. An investigation of the performance of a coaxial HPGe detector operating in a magnetic resonance imaging field

    Energy Technology Data Exchange (ETDEWEB)

    Harkness, L.J., E-mail: ljh@ns.ph.liv.ac.u [Department of Physics, University of Liverpool, Liverpool L69 7ZE (United Kingdom); Boston, A.J.; Boston, H.C.; Cole, P.; Cresswell, J.R.; Filmer, F.; Jones, M.; Judson, D.S.; Nolan, P.J.; Oxley, D.C.; Sampson, J.A.; Scraggs, D.P.; Slee, M.J. [Department of Physics, University of Liverpool, Liverpool L69 7ZE (United Kingdom); Bimson, W.E.; Kemp, G.J. [MARIARC, University of Liverpool, Liverpool L69 3GE (United Kingdom); Groves, J.; Headspith, J.; Lazarus, I.; Simpson, J. [STFC Daresbury Laboratory, Daresbury, Warrington WA4 4AD (United Kingdom); Cooper, R.J. [Joint Institute for Heavy Ion Research, Oak Ridge National Laboratory, Oak Ridge, TN 37831-6371 (United States)

    2011-05-11

    Nuclear medical imaging modalities such as positron emission tomography and single photon emission computed tomography are used to probe physiological functions of the body by detecting gamma rays emitted from biologically targeted radiopharmaceuticals. A system which is capable of simultaneous data acquisition for nuclear medical imaging and magnetic resonance imaging is highly sought after by the medical imaging community. Such a device could provide a more complete medical insight into the functions of the body within a well-defined structural context. However, acquiring simultaneous nuclear/MRI sequences are technically challenging due to the conventional photomultiplier tube readout employed by most existing scintillator detector systems. A promising solution is a nuclear imaging device composed of semiconductor detectors that can be operated with a standard MRI scanner. However, the influence of placing a semiconductor detector such as high purity germanium (HPGe) within or close to the bore of an MRI scanner, where high magnetic fields are present, is not well understood. In this paper, the performance of a HPGe detector operating in a high strength static (B{sub S}) MRI field along with fast switching gradient fields and radiofrequency from the MRI system has been assessed. The influence of the B{sub S} field on the energy resolution of the detector has been investigated for various positions and orientations of the detector within the magnetic field. The results have then been interpreted in terms of the influence of the B{sub S} field on the charge collection properties. MRI images have been acquired with the detector situated at the entrance of the MRI bore to investigate the effects of simultaneous data acquisition on detector performance and MRI imaging.

  20. Large Deployable Reflector (LDR) system concept and technology definition study. Volume 2: Technology assessment and technology development plan

    Science.gov (United States)

    Agnew, Donald L.; Jones, Peter A.

    1989-01-01

    A study was conducted to define reasonable and representative LDR system concepts for the purpose of defining a technology development program aimed at providing the requisite technological capability necessary to start LDR development by the end of 1991. This volume presents thirteen technology assessments and technology development plans, as well as an overview and summary of the LDR concepts. Twenty-two proposed augmentation projects are described (selected from more than 30 candidates). The five LDR technology areas most in need of supplementary support are: cryogenic cooling; astronaut assembly of the optically precise LDR in space; active segmented primary mirror; dynamic structural control; and primary mirror contamination control. Three broad, time-phased, five-year programs were synthesized from the 22 projects, scheduled, and funding requirements estimated.

  1. A novel optical microscope for imaging large embryos and tissue volumes with sub-cellular resolution throughout.

    Science.gov (United States)

    McConnell, Gail; Trägårdh, Johanna; Amor, Rumelo; Dempster, John; Reid, Es; Amos, William Bradshaw

    2016-09-23

    Current optical microscope objectives of low magnification have low numerical aperture and therefore have too little depth resolution and discrimination to perform well in confocal and nonlinear microscopy. This is a serious limitation in important areas, including the phenotypic screening of human genes in transgenic mice by study of embryos undergoing advanced organogenesis. We have built an optical lens system for 3D imaging of objects up to 6 mm wide and 3 mm thick with depth resolution of only a few microns instead of the tens of microns currently attained, allowing sub-cellular detail to be resolved throughout the volume. We present this lens, called the Mesolens, with performance data and images from biological specimens including confocal images of whole fixed and intact fluorescently-stained 12.5-day old mouse embryos.

  2. Dosimetric Coverage of the Prostate, Normal Tissue Sparing, and Acute Toxicity with High-Dose-Rate Brachytherapy for Large Prostate Volumes

    Directory of Open Access Journals (Sweden)

    George Yang

    2015-06-01

    Full Text Available ABSTRACTPurposeTo evaluate dosimetric coverage of the prostate, normal tissue sparing, and acute toxicity with HDR brachytherapy for large prostate volumes.Materials and MethodsOne hundred and two prostate cancer patients with prostate volumes >50 mL (range: 5-29 mL were treated with high-dose-rate (HDR brachytherapy ± intensity modulated radiation therapy (IMRT to 4,500 cGy in 25 daily fractions between 2009 and 2013. HDR brachytherapy monotherapy doses consisted of two 1,350-1,400 cGy fractions separated by 2-3 weeks, and HDR brachytherapy boost doses consisted of two 950-1,150 cGy fractions separated by 4 weeks. Twelve of 32 (38% unfavorable intermediate risk, high risk, and very high risk patients received androgen deprivation therapy. Acute toxicity was graded according to the Common Terminology Criteria for Adverse Events (CTCAE version 4.ResultsMedian follow-up was 14 months. Dosimetric goals were achieved in over 90% of cases. Three of 102 (3% patients developed Grade 2 acute proctitis. No variables were significantly associated with Grade 2 acute proctitis. Seventeen of 102 (17% patients developed Grade 2 acute urinary retention. American Urological Association (AUA symptom score was the only variable significantly associated with Grade 2 acute urinary retention (p=0.04. There was no ≥ Grade 3 acute toxicity.ConclusionsDosimetric coverage of the prostate and normal tissue sparing were adequate in patients with prostate volumes >50 mL. Higher pre-treatment AUA symptom scores increased the relative risk of Grade 2 acute urinary retention. However, the overall incidence of acute toxicity was acceptable in patients with large prostate volumes.

  3. Dosimetric coverage of the prostate, normal tissue sparing, and acute toxicity with high-dose-rate brachytherapy for large prostate volumes

    Energy Technology Data Exchange (ETDEWEB)

    Yang, George; Strom, Tobin J.; Shrinath, Kushagra; Mellon, Eric A.; Fernandez, Daniel C.; Biagioli, Matthew C. [Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL (United States); Wilder, Richard B., E-mail: mcbiagioli@yahoo.com [Cancer Treatment Centers of America, Newnan, GA (United States)

    2015-05-15

    Purpose: to evaluate dosimetric coverage of the prostate, normal tissue sparing, and acute toxicity with HDR brachytherapy for large prostate volumes. Materials and methods: one hundred and two prostate cancer patients with prostate volumes >50 mL (range: 5-29 mL) were treated with high-dose-rate (HDR) brachytherapy ± intensity modulated radiation therapy (IMRT) to 4,500 cGy in 25 daily fractions between 2009 and 2013. HDR brachytherapy monotherapy doses consisted of two 1,350-1,400 cGy fractions separated by 2-3 weeks, and HDR brachytherapy boost doses consisted of two 950-1,150 cGy fractions separated by 4 weeks. Twelve of 32 (38%) unfavorable intermediate risk, high risk, and very high risk patients received androgen deprivation therapy. Acute toxicity was graded according to the Common Terminology Criteria for Adverse Events (CTCAE) version 4. Results: median follow-up was 14 months. Dosimetric goals were achieved in over 90% of cases. Three of 102 (3%) patients developed Grade 2 acute proctitis. No variables were significantly associated with Grade 2 acute proctitis. Seventeen of 102 (17%) patients developed Grade 2 acute urinary retention. American Urological Association (AUA) symptom score was the only variable significantly associated with Grade 2 acute urinary retention (p-0.04). There was no ≥ Grade 3 acute toxicity. Conclusions: dosimetric coverage of the prostate and normal tissue sparing were adequate in patients with prostate volumes >50 mL. Higher pre-treatment AUA symptom scores increased the relative risk of Grade 2 acute urinary retention. However, the overall incidence of acute toxicity was acceptable in patients with large prostate volumes. (author)

  4. High failure rates after (131)I therapy in Graves hyperthyroidism patients with large thyroid volumes, high iodine uptake, and high iodine turnover.

    Science.gov (United States)

    de Jong, Jeroen A F; Verkooijen, Helena M; Valk, Gerlof D; Zelissen, Pierre M J; de Keizer, Bart

    2013-06-01

    The objective of this study was to identify patient characteristics positively and independently associated with I-iodide treatment failure in a large cohort of patients with Graves hyperthyroidism treated with either a calculated "standard" activity of 3.7 MBq/mL (0.1 mCi) or 7.4 MBq/mL (0.2 mCi) of thyroid volume. Data on 385 consecutive patients were prospectively collected. Clinical treatment outcome up to 1 year in relation to thyroid volume, 5- and 24-hour I uptake, 5/24-hour I uptake ratio, and the administered activity of radioiodine were analyzed. Overall treatment results were hypothyroidism in 46%, euthyroidism in 29%, and recurrent hyperthyroidism in 26% of patients. Thyroid volume (P = 0.000), 5/24-hour uptake ratio (P = 0.000), and 5- and 24-hour uptake alone (respectively, P = 0.000 and P = 0.002) were significantly associated with therapy outcome. Patients with a combination of a thyroid volume greater than 50 mL and a 5/24-hour uptake ratio 0.8 or greater showed treatment failure in 70% and 42% (respectively, 3.7 MBq/mL, n = 20; and 7.4 MBq/mL, n = 41).Thyroid volume and 5/24-hour uptake ratio were positively and independently associated with recurrent hyperthyroidism (respectively, odds ratio [OR], 5.3; 95% confidence interval [CI], 2.39-11.76; and OR, 2.97; 95% CI, 1.59-5.59). Higher activities of 7.4 MBq/mL I were associated with a lower risk of treatment failure (OR, 0.34; 95% CI, 0.18-0.62). Large thyroid volumes and high 5/24-hour uptake ratios are positively and independently associated with recurrent hyperthyroidism following I therapy in Graves hyperthyroidism. Higher success rates can be achieved when account is taken of these poor prognostic factors. In consequence, these patients should be treated with activities greater than 7.4 MBq/mL.

  5. META II: Formal Co-Verification of Correctness of Large-Scale Cyber-Physical Systems during Design. Volume 1

    Science.gov (United States)

    2011-08-01

    design space is large. His research contributions are to the field of Decision-based Design, specifically in linking consumer preferences and...Integrating Consumer Preferences into Engineering Design, to be published in 2012. He received his PhD from Northwestern University in Mechanical

  6. The Limits and Possibilities of International Large-Scale Assessments. Education Policy Brief. Volume 9, Number 2, Spring 2011

    Science.gov (United States)

    Rutkowski, David J.; Prusinski, Ellen L.

    2011-01-01

    The staff of the Center for Evaluation & Education Policy (CEEP) at Indiana University is often asked about how international large-scale assessments influence U.S. educational policy. This policy brief is designed to provide answers to some of the most frequently asked questions encountered by CEEP researchers concerning the three most popular…

  7. Analysis of Lung Tumor Motion in a Large Sample: Patterns and Factors Influencing Precise Delineation of Internal Target Volume

    Energy Technology Data Exchange (ETDEWEB)

    Knybel, Lukas [Department of Oncology, University Hospital Ostrava, Ostrava (Czech Republic); VŠB-Technical University of Ostrava, Ostrava (Czech Republic); Cvek, Jakub, E-mail: Jakub.cvek@fno.cz [Department of Oncology, University Hospital Ostrava, Ostrava (Czech Republic); Molenda, Lukas; Stieberova, Natalie; Feltl, David [Department of Oncology, University Hospital Ostrava, Ostrava (Czech Republic)

    2016-11-15

    Purpose/Objective: To evaluate lung tumor motion during respiration and to describe factors affecting the range and variability of motion in patients treated with stereotactic ablative radiation therapy. Methods and Materials: Log file analysis from online respiratory tumor tracking was performed in 145 patients. Geometric tumor location in the lungs, tumor volume and origin (primary or metastatic), sex, and tumor motion amplitudes in the superior-inferior (SI), latero-lateral (LL), and anterior-posterior (AP) directions were recorded. Tumor motion variability during treatment was described using intrafraction/interfraction amplitude variability and tumor motion baseline changes. Tumor movement dependent on the tumor volume, position and origin, and sex were evaluated using statistical regression and correlation analysis. Results: After analysis of >500 hours of data, the highest rates of motion amplitudes, intrafraction/interfraction variation, and tumor baseline changes were in the SI direction (6.0 ± 2.2 mm, 2.2 ± 1.8 mm, 1.1 ± 0.9 mm, and −0.1 ± 2.6 mm). The mean motion amplitudes in the lower/upper geometric halves of the lungs were significantly different (P<.001). Motion amplitudes >15 mm were observed only in the lower geometric quarter of the lungs. Higher tumor motion amplitudes generated higher intrafraction variations (R=.86, P<.001). Interfraction variations and baseline changes >3 mm indicated tumors contacting mediastinal structures or parietal pleura. On univariate analysis, neither sex nor tumor origin (primary vs metastatic) was an independent predictive factor of different movement patterns. Metastatic lesions in women, but not men, showed significantly higher mean amplitudes (P=.03) and variability (primary, 2.7 mm; metastatic, 4.9 mm; P=.002) than primary tumors. Conclusion: Online tracking showed significant irregularities in lung tumor movement during respiration. Motion amplitude was significantly lower in upper lobe

  8. Analysis of Lung Tumor Motion in a Large Sample: Patterns and Factors Influencing Precise Delineation of Internal Target Volume

    International Nuclear Information System (INIS)

    Knybel, Lukas; Cvek, Jakub; Molenda, Lukas; Stieberova, Natalie; Feltl, David

    2016-01-01

    Purpose/Objective: To evaluate lung tumor motion during respiration and to describe factors affecting the range and variability of motion in patients treated with stereotactic ablative radiation therapy. Methods and Materials: Log file analysis from online respiratory tumor tracking was performed in 145 patients. Geometric tumor location in the lungs, tumor volume and origin (primary or metastatic), sex, and tumor motion amplitudes in the superior-inferior (SI), latero-lateral (LL), and anterior-posterior (AP) directions were recorded. Tumor motion variability during treatment was described using intrafraction/interfraction amplitude variability and tumor motion baseline changes. Tumor movement dependent on the tumor volume, position and origin, and sex were evaluated using statistical regression and correlation analysis. Results: After analysis of >500 hours of data, the highest rates of motion amplitudes, intrafraction/interfraction variation, and tumor baseline changes were in the SI direction (6.0 ± 2.2 mm, 2.2 ± 1.8 mm, 1.1 ± 0.9 mm, and −0.1 ± 2.6 mm). The mean motion amplitudes in the lower/upper geometric halves of the lungs were significantly different (P 15 mm were observed only in the lower geometric quarter of the lungs. Higher tumor motion amplitudes generated higher intrafraction variations (R=.86, P 3 mm indicated tumors contacting mediastinal structures or parietal pleura. On univariate analysis, neither sex nor tumor origin (primary vs metastatic) was an independent predictive factor of different movement patterns. Metastatic lesions in women, but not men, showed significantly higher mean amplitudes (P=.03) and variability (primary, 2.7 mm; metastatic, 4.9 mm; P=.002) than primary tumors. Conclusion: Online tracking showed significant irregularities in lung tumor movement during respiration. Motion amplitude was significantly lower in upper lobe tumors; higher interfraction amplitude variability indicated tumors in contact

  9. 'Dip-sticks' calibration handles self-attenuation and coincidence effects in large-volume gamma-ray spectrometry

    CERN Document Server

    Wolterbeek, H T

    2000-01-01

    Routine gamma-spectrometric analyses of samples with low-level activities (e.g. food, water, environmental and industrial samples) are often performed in large samples, placed close to the detector. In these geometries, detection sensitivity is improved but large errors are introduced due to self-attenuation and coincidence summing. Current approaches to these problems comprise computational methods and spiked standard materials. However, the first are often regarded as too complex for practical routine use, the latter never fully match real samples. In the present study, we introduce a dip-sticks calibration as a fast and easy practical solution to this quantification problem in a routine analytical setting. In the proposed set-up, calibrations are performed within the sample itself, thus making it a broadly accessible matching-reference approach, which is principally usable for all sample matrices.

  10. System of large transport containers for waste from dismantling light water and gas-cooled nuclear reactors. Volume 2

    International Nuclear Information System (INIS)

    Price, M.S.T.

    1986-09-01

    This report deals with the operational, radiological and economic aspects of transport as well as conceptual designs of large containers for the transport of radioactive decommissioning wastes from nuclear power plants within the member states of the European Economic Community. The means of transport, the costs and radiological detriment are considered, and conceptual designs of containers are described. Recommendations are made for further studies. (U.K.)

  11. Neutron multicounter detector for investigation of content and spatial distribution of fission materials in large volume samples

    International Nuclear Information System (INIS)

    Swiderska-Kowalczyk, M.; Starosta, W.; Zoltowski, T.

    1998-01-01

    The experimental device is a neutron coincidence well counter. It can be applied for passive assay of fissile - especially for plutonium bearing - materials. It consist of a set of 3 He tubes placed inside a polyethylene moderator; outputs from the tubes, first processed by preamplifier/amplifier/discriminator circuits, are then analysed using neutron correlator connected with a PC, and correlation techniques implemented in software. Such a neutron counter allows for determination of plutonium mass ( 240 Pu effective mass) in nonmultiplying samples having fairly big volume (up to 0.14 m 3 ). For determination of neutron sources distribution inside the sample, the heuristic methods based on hierarchical cluster analysis are applied. As an input parameters, amplitudes and phases of two-dimensional Fourier transformation of the count profiles matrices for known point sources distributions and for the examined samples, are taken. Such matrices are collected by means of sample scanning by detection head. During clustering process, counts profiles for unknown samples fitted into dendrograms using the 'proximity' criterion of the examined sample profile to standard samples profiles. Distribution of neutron sources in an examined sample is then evaluated on the basis of comparison with standard sources distributions. (author)

  12. Development of a unified sizing method for gas radiation heating facilities used in large-volume buildings; Developpement d'une methode de dimensionnement unifiee d'installations de chauffage radiant gaz pour les batiments de grand volume

    Energy Technology Data Exchange (ETDEWEB)

    Jimenez, M.; Bego, L.; Douls, Y.; Le Dean, P.; Paradowski, V. [Gaz de France, GDF, Dir. de la Recherche, 75 - Paris (France)

    2000-07-01

    Builders now have perfect command of the natural gas heating technique used for large-volume buildings. However, the sizing of heating facilities still leaves grounds for discussion, whatever the energies actually used. Accordingly, between 1997 and 1999, the ATG (technical association of the Gas industry in France), seven French manufacturers of 'large volume' heating equipment, the Chaleur Et Rayonnement (CER) association and Gaz de France decided to collaborate and develop a 'unified sizing method' for heating facilities using radiating emitters. During the first year of the study, the above partners worked on the said method (theoretical thermal study of the radiative phenomena, and then adaptation to the methods currently used by the various manufacturers). In 1998, with the support of the ADEME (the French environment and energy control agency), the partners tested the method on five industrial buildings (studying the thermal behavior and making air renewal measurements with search gases). This work made it possible to either confirm or adapt the theoretical evaluations which had been made originally. In 1999, a software program was produced to make the developed method more user friendly. The program can be used to determine the power to be installed, but also to assess the quality of the chosen configuration of the emitters (unit power, inclination, orientation) for optimum customer comfort. (authors)

  13. Effect of NaOH on large-volume sample stacking of haloacetic acids in capillary zone electrophoresis with a low-pH buffer.

    Science.gov (United States)

    Tu, Chuanhong; Zhu, Lingyan; Ang, Chay Hoon; Lee, Hian Kee

    2003-06-01

    Large-volume sample stacking (LVSS) is an effective on-capillary sample concentration method in capillary zone electrophoresis, which can be applied to the sample in a low-conductivity matrix. NaOH solution is commonly used to back-extract acidic compounds from organic solvent in sample pretreatment. The effect of NaOH as sample matrix on LVSS of haloacetic acids was investigated in this study. It was found that the presence of NaOH in sample did not compromise, but rather help the sample stacking performance if a low pH background electrolyte (BGE) was used. The sensitivity enhancement factor was higher than the case when sample was dissolved in pure water or diluted BGE. Compared with conventional injection (0.4% capillary volume), 97-120-fold sensitivity enhancement in terms of peak height was obtained without deterioration of separation with an injection amount equal to 20% of the capillary volume. This method was applied to determine haloacetic acids in tap water by combination with liquid-liquid extraction and back-extraction into NaOH solution. Limits of detection at sub-ppb levels were obtained for real samples with direct UV detection.

  14. On Assumptions in Development of a Mathematical Model of Thermo-gravitational Convection in the Large Volume Process Tanks Taking into Account Fermentation

    Directory of Open Access Journals (Sweden)

    P. M. Shkapov

    2015-01-01

    Full Text Available The paper provides a mathematical model of thermo-gravity convection in a large volume vertical cylinder. The heat is removed from the product via the cooling jacket at the top of the cylinder. We suppose that a laminar fluid motion takes place. The model is based on the NavierStokes equation, the equation of heat transfer through the wall, and the heat transfer equation. The peculiarity of the process in large volume tanks was the distribution of the physical parameters of the coordinates that was taken into account when constructing the model. The model corresponds to a process of wort beer fermentation in the cylindrical-conical tanks (CCT. The CCT volume is divided into three zones and for each zone model equations was obtained. The first zone has an annular cross-section and it is limited to the height by the cooling jacket. In this zone the heat flow from the cooling jacket to the product is uppermost. Model equation of the first zone describes the process of heat transfer through the wall and is presented by linear inhomogeneous differential equation in partial derivatives that is solved analytically. For the second and third zones description there was a number of engineering assumptions. The fluid was considered Newtonian, viscous and incompressible. Convective motion considered in the Boussinesq approximation. The effect of viscous dissipation is not considered. The topology of fluid motion is similar to the cylindrical Poiseuille. The second zone model consists of the Navier-Stokes equations in cylindrical coordinates with the introduction of a simplified and the heat equation in the liquid layer. The volume that is occupied by an upward convective flow pertains to the third area. Convective flows do not mix and do not exchange heat. At the start of the process a medium has the same temperature and a zero initial velocity in the whole volume that allows us to specify the initial conditions for the process. The paper shows the

  15. Automated transmission-mode scanning electron microscopy (tSEM for large volume analysis at nanoscale resolution.

    Directory of Open Access Journals (Sweden)

    Masaaki Kuwajima

    Full Text Available Transmission-mode scanning electron microscopy (tSEM on a field emission SEM platform was developed for efficient and cost-effective imaging of circuit-scale volumes from brain at nanoscale resolution. Image area was maximized while optimizing the resolution and dynamic range necessary for discriminating key subcellular structures, such as small axonal, dendritic and glial processes, synapses, smooth endoplasmic reticulum, vesicles, microtubules, polyribosomes, and endosomes which are critical for neuronal function. Individual image fields from the tSEM system were up to 4,295 µm(2 (65.54 µm per side at 2 nm pixel size, contrasting with image fields from a modern transmission electron microscope (TEM system, which were only 66.59 µm(2 (8.160 µm per side at the same pixel size. The tSEM produced outstanding images and had reduced distortion and drift relative to TEM. Automated stage and scan control in tSEM easily provided unattended serial section imaging and montaging. Lens and scan properties on both TEM and SEM platforms revealed no significant nonlinear distortions within a central field of ∼100 µm(2 and produced near-perfect image registration across serial sections using the computational elastic alignment tool in Fiji/TrakEM2 software, and reliable geometric measurements from RECONSTRUCT™ or Fiji/TrakEM2 software. Axial resolution limits the analysis of small structures contained within a section (∼45 nm. Since this new tSEM is non-destructive, objects within a section can be explored at finer axial resolution in TEM tomography with current methods. Future development of tSEM tomography promises thinner axial resolution producing nearly isotropic voxels and should provide within-section analyses of structures without changing platforms. Brain was the test system given our interest in synaptic connectivity and plasticity; however, the new tSEM system is readily applicable to other biological systems.

  16. Numerical Study for a Large Volume Droplet on the Dual-rough Surface: Apparent Contact Angle, Contact Angle Hysteresis and Transition Barrier.

    Science.gov (United States)

    Dong, Jian; Jin, Yanli; Dong, He; Liu, Jiawei; Ye, Senbin

    2018-06-14

    The profile, apparent contact angle (ACA), contact angle hysteresis (CAH) and wetting state transmission energy barrier (WSTEB) are important static and dynamic properties of a large volume droplet on the hierarchical surface. Understanding them can provide us with important insights to functional surfaces and promote the application in corresponding areas. In this paper, we established three theoretical models (Model 1, Model 2 and Model 3) and corresponding numerical methods, which were obtained by the free energy minimization and the nonlinear optimization algorithm, to predict the profile, ACA, CAH and WSTEB of a large volume droplet on the horizontal regular dual-rough surface. In consideration of the gravity, the energy barrier on the contact circle, the dual heterogenous structures and their roughness on the surface, the models are more universal and accurate than previous models. It showed that the predictions of the models were in good agreement with the results from the experiment or literature. The models are promising to become novel design approaches of functional surfaces, which are frequently applied in microfluidic chips, water self-catchment system and dropwise condensation heat transfer system.

  17. Use of nitrogen to remove solvent from through oven transfer adsorption desorption interface during analysis of polycyclic aromatic hydrocarbons by large volume injection in gas chromatography.

    Science.gov (United States)

    Áragón, Alvaro; Toledano, Rosa M; Cortés, José M; Vázquez, Ana M; Villén, Jesús

    2014-04-25

    The through oven transfer adsorption desorption (TOTAD) interface allows large volume injection (LVI) in gas chromatography and the on-line coupling of liquid chromatography and gas chromatography (LC-GC), enabling the LC step to be carried out in normal as well as in reversed phase. However, large amounts of helium, which is both expensive and scarce, are necessary for solvent elimination. We describe how slight modification of the interface and the operating mode allows nitrogen to be used during the solvent elimination steps. In order to evaluate the performance of the new system, volumes ranging from 20 to 100μL of methanolic solutions of four polycyclic aromatic hydrocarbons (PAHs) were sampled. No significant differences were found in the repeatability and sensitivity of the analyses of standard PAH solutions when using nitrogen or helium. The performance using the proposed modification was similar and equally satisfactory when using nitrogen or helium for solvent elimination in the TOTAD interface. In conclusion, the use of nitrogen will make analyses less expensive. Copyright © 2014 Elsevier B.V. All rights reserved.

  18. Large-volume constant-concentration sampling technique coupling with surface-enhanced Raman spectroscopy for rapid on-site gas analysis.

    Science.gov (United States)

    Zhang, Zhuomin; Zhan, Yisen; Huang, Yichun; Li, Gongke

    2017-08-05

    In this work, a portable large-volume constant-concentration (LVCC) sampling technique coupling with surface-enhanced Raman spectroscopy (SERS) was developed for the rapid on-site gas analysis based on suitable derivatization methods. LVCC sampling technique mainly consisted of a specially designed sampling cell including the rigid sample container and flexible sampling bag, and an absorption-derivatization module with a portable pump and a gas flowmeter. LVCC sampling technique allowed large, alterable and well-controlled sampling volume, which kept the concentration of gas target in headspace phase constant during the entire sampling process and made the sampling result more representative. Moreover, absorption and derivatization of gas target during LVCC sampling process were efficiently merged in one step using bromine-thiourea and OPA-NH 4 + strategy for ethylene and SO 2 respectively, which made LVCC sampling technique conveniently adapted to consequent SERS analysis. Finally, a new LVCC sampling-SERS method was developed and successfully applied for rapid analysis of trace ethylene and SO 2 from fruits. It was satisfied that trace ethylene and SO 2 from real fruit samples could be actually and accurately quantified by this method. The minor concentration fluctuations of ethylene and SO 2 during the entire LVCC sampling process were proved to be gas targets from real samples by SERS. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. Magma Chamber Model of Batur Caldera, Bali, Indonesia: Compositional Variation of Two Facies, Large-Volume Dacitic Ignimbrites

    Directory of Open Access Journals (Sweden)

    Igan S. Sutawidjaja

    2015-05-01

    Full Text Available DOI:10.17014/ijog.2.2.111-124Batur is one of the finest known calderas on Earth, and is the source of at least two major ignimbrite eruptions with a combined volume of some 84 km3 and 19 km3. These ignimbrites have a similar compositions, raising the question of whether they are geneticaly related. The Batur Ignimbrite-1 (BI-1 is crystal poor, containing rhyodacitic (68 - 70wt % SiO2, white to grey pumices and partly welded and unwelded. The overlying Batur Ignimbrite-2 (BI-2 is a homogeneous grey to black dacitic pumices (64 - 66 wt % SiO2, unwelded and densely welded (40 - 60% vesicularity, crystal and lithic rich. Phase equilibria indicate that the Batur magma equilibrated at temperatures of 1100 - 1300oC with melt water contents of 3 - 6 wt%. The post-eruptive Batur magma was cooler (<1100oC and it is melt more water rich (> 6 wt % H2O. A pressure of 20 kbar is infered from mineral barometry for the Batur magma chamber. Magmatic chamber model is one in which crystals and melt separate from a convecting Batur magma by density differences, resulting in a stratified magma chamber with a homogeneous central zone, a crystal-rich accumulation zone near the walls or base, and a buoyant, melt-rich zone near the top. This is consistent with the estimated magma temperatures and densities: the pre-eruptive BI-1 magma was hoter (1300oC and more volatile rich (6 wt % H2O with density 2.25 g/cm3 than the BI-2 magma (1200oC; 4 wt % H2O in density was higher (2.50 g/cm3. Batur melt characteristics and intensive parameters are consistent with a volatile oversaturation-driven eruption. However, the higher H2O content, high viscosity and low crystal content of the BI-1 magma imply an external eruption trigger.

  20. Calibration comparative results for X - and gamma ray spectrometry with HPGe and BEGe detectors for a radon reference chamber

    International Nuclear Information System (INIS)

    Zoran, Maria; Paul, Annette; Arnold, Dirk

    2002-01-01

    Inhaled decay products of 222 Rn are the dominant components of the natural radiation exposure being responsible for about 30% of the whole human radioactive exposure. Field instruments for 222 Rn and his progeny monitoring are calibrated in 'radon climate rooms', where it is possible to vary and monitor 222 Rn and the indoor air parameters ( temperature, humidity, ventilation rate, aerosol concentration). German radon reference chamber used was developed and installed at the Physikalisch-Technische Bundesanstalt in order to serve as a metrological standard for radon and his progeny calibration of active and passive, indoor and outdoor radon monitoring devices in air climate. The basic parts of experimental setup for this γ and X -ray spectrometry analysis consists of a γ-X ray source in a lead shield/collimator, the detectors, the electronics necessary for pulse-height analysis (PHA) to obtain energy spectra. For calibrating system with 226 Ra standard sources (multienergy X ray and gamma emitters), two germanium detectors HPGe (12.5 nominal efficiency) and BEGe (22.5 nominal efficiency) were used. Germanium detectors are semiconductor diodes having a P-I-N structure in which the Intrinsic (I) region is sensitive to ionizing radiation, particularly X-rays and gamma rays. The BEGe is designed with an electrode structure that enhances low energy resolution and is fabricated from selected germanium having an impurity profile that improves charge collection (thus resolution and peak shape) at high energies which is really important in analysis of the complex spectra for uranium and finally for 226 Ra. MAESTRO MCA software and GNUPLOT program were used for spectra acquisition and spectra analysis, respectively . The main aim of this paper was to do a comparatively analysis of the detector performances for this radon chamber spectrometric chain. The calibration data analysis includes energy calibrations for both detection systems as well as comparative X and gamma

  1. JUICE: a data management system that facilitates the analysis of large volumes of information in an EST project workflow.

    Science.gov (United States)

    Latorre, Mariano; Silva, Herman; Saba, Juan; Guziolowski, Carito; Vizoso, Paula; Martinez, Veronica; Maldonado, Jonathan; Morales, Andrea; Caroca, Rodrigo; Cambiazo, Veronica; Campos-Vargas, Reinaldo; Gonzalez, Mauricio; Orellana, Ariel; Retamales, Julio; Meisel, Lee A

    2006-11-23

    Expressed sequence tag (EST) analyses provide a rapid and economical means to identify candidate genes that may be involved in a particular biological process. These ESTs are useful in many Functional Genomics studies. However, the large quantity and complexity of the data generated during an EST sequencing project can make the analysis of this information a daunting task. In an attempt to make this task friendlier, we have developed JUICE, an open source data management system (Apache + PHP + MySQL on Linux), which enables the user to easily upload, organize, visualize and search the different types of data generated in an EST project pipeline. In contrast to other systems, the JUICE data management system allows a branched pipeline to be established, modified and expanded, during the course of an EST project. The web interfaces and tools in JUICE enable the users to visualize the information in a graphical, user-friendly manner. The user may browse or search for sequences and/or sequence information within all the branches of the pipeline. The user can search using terms associated with the sequence name, annotation or other characteristics stored in JUICE and associated with sequences or sequence groups. Groups of sequences can be created by the user, stored in a clipboard and/or downloaded for further analyses. Different user profiles restrict the access of each user depending upon their role in the project. The user may have access exclusively to visualize sequence information, access to annotate sequences and sequence information, or administrative access. JUICE is an open source data management system that has been developed to aid users in organizing and analyzing the large amount of data generated in an EST Project workflow. JUICE has been used in one of the first functional genomics projects in Chile, entitled "Functional Genomics in nectarines: Platform to potentiate the competitiveness of Chile in fruit exportation". However, due to its ability to

  2. JUICE: a data management system that facilitates the analysis of large volumes of information in an EST project workflow

    Directory of Open Access Journals (Sweden)

    Martinez Veronica

    2006-11-01

    Full Text Available Abstract Background Expressed sequence tag (EST analyses provide a rapid and economical means to identify candidate genes that may be involved in a particular biological process. These ESTs are useful in many Functional Genomics studies. However, the large quantity and complexity of the data generated during an EST sequencing project can make the analysis of this information a daunting task. Results In an attempt to make this task friendlier, we have developed JUICE, an open source data management system (Apache + PHP + MySQL on Linux, which enables the user to easily upload, organize, visualize and search the different types of data generated in an EST project pipeline. In contrast to other systems, the JUICE data management system allows a branched pipeline to be established, modified and expanded, during the course of an EST project. The web interfaces and tools in JUICE enable the users to visualize the information in a graphical, user-friendly manner. The user may browse or search for sequences and/or sequence information within all the branches of the pipeline. The user can search using terms associated with the sequence name, annotation or other characteristics stored in JUICE and associated with sequences or sequence groups. Groups of sequences can be created by the user, stored in a clipboard and/or downloaded for further analyses. Different user profiles restrict the access of each user depending upon their role in the project. The user may have access exclusively to visualize sequence information, access to annotate sequences and sequence information, or administrative access. Conclusion JUICE is an open source data management system that has been developed to aid users in organizing and analyzing the large amount of data generated in an EST Project workflow. JUICE has been used in one of the first functional genomics projects in Chile, entitled "Functional Genomics in nectarines: Platform to potentiate the competitiveness of Chile in

  3. Environmental Monitoring and Characterization of Radiation Sources on UF Campus Using a Large Volume NaI Detector

    Science.gov (United States)

    Bruner, Jesse A.; Gardiner, Hannah E.; Jordan, Kelly A.; Baciak, James E.

    2016-09-01

    Environmental radiation surveys are important for applications such as safety and regulations. This is especially true for areas exposed to emissions from nuclear reactors, such as the University of Florida Training Reactor (UFTR). At the University of Florida, surveys are performed using the RSX-1 NaI detector, developed by Radiation Solutions Inc. The detector uses incoming gamma rays and an Advanced Digital Spectrometer module to produce a linear energy spectrum. These spectra can then be analyzed in real time with a personal computer using the built in software, RadAssist. We report on radiation levels around the University of Florida campus using two mobile detection platforms, car-borne and cart-borne. The car-borne surveys provide a larger, broader map of campus radiation levels. On the other hand, cart-borne surveys provide a more detailed radiation map because of its ability to reach places on campus cars cannot go. Throughout the survey data, there are consistent radon decay product energy peaks in addition to other sources such as medical I-131 found in a large crowd of people. Finally, we investigate further applications of this mobile detection platform, such as tracking the Ar-41 plume emitted from the UFTR and detection of potential environmental hazards.

  4. Developing a strategy to speed up large-scale adoption of compressed-natural-gas-driven (CNG) cars. Volume 1

    International Nuclear Information System (INIS)

    Egmond, Cees; Houtman, Simone; Jonkers, R.; Gelissen, R.

    2007-01-01

    Large-scale adoption of environmentally friendly, clean, silent and CO 2 -neutral technological innovations into the market is necessary to reduce the human causes of the greenhouse effect and global warming. In theory, an innovation diffuses smoothly into the market following an S-shaped curve when the number of adopters is plotted against time. In practice, diffusion of innovation does not move smoothly from left to right on the S-shaped curve. Fundamental differences in the adoption characteristics between the visionary early adopters and the pragmatic mainstream cause diffusion to stop before reaching the mainstream market segment. This 'chasm' in the diffusion process is not the result of bad technology or bad products, but rather the result of 'incomplete' products that do not meet the needs of the pragmatic mainstream. In this paper, we report on a case study, conducted in the Netherlands, aimed at speeding up the adoption of the CNG car. This study contains an analysis of the market segments within a target group of local fleet owners. We used survey data covering about 200 local fleet owners. Through structured interviews and a questionnaire, we identified a niche group of the mainstream that would be most likely to adopt the CNG car. This niche is the group to target in a marketing strategy aimed at crossing the chasm. A focus-group discussion held with members of the niche identified the conditions under which the niche actors would consider buying CNG cars. Based on the results of this focus group and the niche market analysis, we concluded that the marketing of the CNG car is still in its beginning phase and has to focus on the early market. Following our recommendations, car dealers and the municipality of Leeuwarden are now developing a plan for marketing the CNG car. The marketing will focus on the early market as the first step into the mainstream

  5. Factors affecting autologous peripheral blood hematopoietic stem cell collections by large-volume leukapheresis: a single center experience

    Directory of Open Access Journals (Sweden)

    Araci Massami Sakashita

    2011-06-01

    Full Text Available Objective: To evaluate factors affecting peripheral bloodhematopoietic stem cell yield in patients undergoing large-volumeleukapheresis for autologous peripheral blood stem cell collection.Methods: Data from 304 consecutive autologous peripheral bloodstem cell donors mobilized with hematopoietic growth factor (usually G-CSF, associated or not with chemotherapy, at Hospital Israelita Albert Einstein between February 1999 and June 2010 were retrospectively analyzed. The objective was to obtain at least 2 x 106CD34+ cells/kg of body weight. Pre-mobilization factors analyzedincluded patient’s age, gender and diagnosis. Post mobilizationparameters evaluated were pre-apheresis peripheral white bloodcell count, immature circulating cell count, mononuclear cell count,peripheral blood CD34+ cell count, platelet count, and hemoglobinlevel. The effect of pre and post-mobilization factors on hematopoietic stem cell collection yield was investigated using logistic regression analysis (univariate and multivariate approaches. Results: Premobilization factors correlating to poor CD34+ cell yield in univariate analysis were acute myeloid leukemia (p = 0.017 and other hematological diseases (p = 0.023. Significant post-mobilization factors included peripheral blood immature circulating cells (p = 0.001, granulocytes (p = 0.002, hemoglobin level (p = 0.016, and CD34+ cell concentration (p < 0.001 in the first harvesting day. However, according to multivariate analysis, peripheral blood CD34+ cell content (p < 0.001 was the only independent factor that significantly correlated to poor hematopoietic stem cell yield. Conclusion: In this study, peripheral blood CD34+ cell concentration was the only factor significantly correlated to yield in patients submitted to for autologous collection.

  6. Developing a strategy to speed up large-scale adoption of compressed-natural-gas-driven (CNG) cars. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Egmond, Cees; Houtman, Simone; Jonkers, R.; Gelissen, R. [SenterNovem (Netherlands)

    2007-07-01

    Large-scale adoption of environmentally friendly, clean, silent and CO{sub 2}-neutral technological innovations into the market is necessary to reduce the human causes of the greenhouse effect and global warming. In theory, an innovation diffuses smoothly into the market following an S-shaped curve when the number of adopters is plotted against time. In practice, diffusion of innovation does not move smoothly from left to right on the S-shaped curve. Fundamental differences in the adoption characteristics between the visionary early adopters and the pragmatic mainstream cause diffusion to stop before reaching the mainstream market segment. This 'chasm' in the diffusion process is not the result of bad technology or bad products, but rather the result of 'incomplete' products that do not meet the needs of the pragmatic mainstream. In this paper, we report on a case study, conducted in the Netherlands, aimed at speeding up the adoption of the CNG car. This study contains an analysis of the market segments within a target group of local fleet owners. We used survey data covering about 200 local fleet owners. Through structured interviews and a questionnaire, we identified a niche group of the mainstream that would be most likely to adopt the CNG car. This niche is the group to target in a marketing strategy aimed at crossing the chasm. A focus-group discussion held with members of the niche identified the conditions under which the niche actors would consider buying CNG cars. Based on the results of this focus group and the niche market analysis, we concluded that the marketing of the CNG car is still in its beginning phase and has to focus on the early market. Following our recommendations, car dealers and the municipality of Leeuwarden are now developing a plan for marketing the CNG car. The marketing will focus on the early market as the first step into the mainstream.

  7. Direct and precise determination of environmental radionuclides in solid materials using a modified Marinelli beaker and a HPGe detector

    International Nuclear Information System (INIS)

    Seo, B.K.; Lee, D.W.; Lee, K.Y.; Yoon, Y.Y.

    2001-01-01

    A simple but precise detection method was studied for the determination of natural radionuclides using a conventional HPGe detector. A new aluminium beaker instead of a plastic Marinelli beaker was constructed and examined to reach radioactive equilibrium conditions between radon and its daughter elements without the escape of gaseous radon. Using this beaker fifteen natural radionuclides from three natural decay series could be determined by direct γ-ray measurement and sixteen radionuclides could be determined indirectly after radioactive equilibrium had been reached. Analytical results from ground water were compared with those from conventional α spectroscopy and the results agreed well within 12% difference. Nitrogen gas purge was used to replace the surrounding air of the detector to obtain a stable background and reducing the interference of radon daughter nuclides in the atmosphere. The use of nitrogen purging and the aluminium Marinelli beaker results in an approximately tenfold increase of sensitivity and a decrease of the detection limit of 226 Ra to about 0.74 Bq kg -1 in soil samples. (orig.)

  8. Direct and precise determination of environmental radionuclides in solid materials using a modified Marinelli beaker and a HPGe detector.

    Science.gov (United States)

    Seo, B K; Lee, K Y; Yoon, Y Y; Lee, D W

    2001-06-01

    A simple but precise detection method was studied for the determination of natural radionuclides using a conventional HPGe detector. A new aluminium beaker instead of a plastic Marinelli beaker was constructed and examined to reach radioactive equilibrium conditions between radon and its daughter elements without the escape of gaseous radon. Using this beaker fifteen natural radionuclides from three natural decay series could be determined by direct gamma-ray measurement and sixteen radionuclides could be determined indirectly after radioactive equilibrium had been reached. Analytical results from ground water were compared with those from conventional alpha spectroscopy and the results agreed well within 12% difference. Nitrogen gas purge was used to replace the surrounding air of the detector to obtain a stable background and reducing the interference of radon daughter nuclides in the atmosphere. The use of nitrogen purging and the aluminium Marinelli beaker results in an approximately tenfold increase of sensitivity and a decrease of the detection limit of 226Ra to about 0.74 Bq kg(-1) in soil samples.

  9. Gamma-ray impurities of {sup 111}In, {sup 201}Tl, {sup 177}Lu and {sup 99m}Tc determined by means of a HPGE spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Koskinas, Marina F.; Almeida, Jamille da Silveira; Moreira, Denise Simões; Semmler, Renato; Dias, Mauro da Silva, E-mail: koskinas@ipen.br, E-mail: jamillealmeida@gmail.com, E-mail: denise.moreira@ipen.br, E-mail: rsemmler@ipen.br, E-mail: msdias@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2017-11-01

    This work aims to present the radioactive impurities gamma rays emitters detected in some radiopharmaceuticals widely applied to diagnosis and therapy purposes, supplied to nuclear medicine services in Brazil by the Radiopharmaceutical Center(CR) of Nuclear and Energy Research Institute, IPEN, in São Paulo. The analysis was undertaken by means of an HPGe gamma spectrometer. The radiopharmaceuticals analyzed were: {sup 111}In, {sup 201}Tl, {sup 177}Lu and {sup 99m}Tc. (author)

  10. Experimental and simulated efficiency of a HPGe detector in the energy range of 0.06∼11 MeV

    International Nuclear Information System (INIS)

    Park, Chang Su; Choi, H. D.; Sun, Gwang Min

    2003-01-01

    The full energy peak efficiency of a Hyper Pure Germanium (HPGe) detector was calibrated in a wide energy range from 0.06 to 11 MeV. Both the experimental technique and the Monte Carlo method were used for the efficiency calibration. The measurement was performed using the standard radioisotopes in the low energy region of 60∼1408 keV, which was further extended up to 11 MeV by using the 14 N(n,γ) and 35 Cl(n,γ) reactions. The GEANT Monte Carlo code was used for efficiency calculation. The calculated efficiency had the same dependency on the γ-ray energy with the measurement, and the discrepancy between the calculation and the measurement was minimized by fine-tuning of the detector geometry. From the calculated result, the efficiency curve of the HPGe detector was reliably determined particularly in the high energy region above several MeV, where the number of measured efficiency points is relatively small despite the wide energy region. The calculated efficiency agreed with the measurement within about 7%. In addition to the efficiency calculation, the origin of the local minimum near 600 keV on the efficiency curve was analyzed as a general characteristics of a HPGe detector

  11. Pre-column dilution large volume injection ultra-high performance liquid chromatography-tandem mass spectrometry for the analysis of multi-class pesticides in cabbages.

    Science.gov (United States)

    Zhong, Qisheng; Shen, Lingling; Liu, Jiaqi; Yu, Dianbao; Li, Siming; Yao, Jinting; Zhan, Song; Huang, Taohong; Hashi, Yuki; Kawano, Shin-ichi; Liu, Zhaofeng; Zhou, Ting

    2016-04-15

    Pre-column dilution large volume injection (PD-LVI), a novel sample injection technique for reverse phase ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS), was developed in this study. The PD-LVI UHPLC-MS/MS system was designed by slightly modifying the commercial UHPLC-MS/MS equipment with a mixer chamber. During the procedure of PD-LVI, sample solution of 200μL was directly carried by the organic mobile phase to the mixer and diluted with the aqueous mobile phase. After the mixture was introduced to the UHPLC column in a mobile phase of acetonitrile-water (15/85, v/v), the target analytes were stacked on the head of the column until following separation. Using QuEChERS extraction, no additional steps such as solvent evaporation or residue redissolution were needed before injection. The features of PD-LVI UHPLC-MS/MS system were systematically investigated, including the injection volume, the mixer volume, the precondition time and the gradient elution. The efficiency of this approach was demonstrated by direct analysis of 24 pesticides in cabbages. Under the optimized conditions, low limits of detection (0.00074-0.8 ng/kg) were obtained. The recoveries were in the range of 63.3-109% with relative standard deviations less than 8.1%. Compared with common UHPLC-MS/MS technique, PD-LVI UHPLC-MS/MS showed significant advantages such as excellent sensitivity and reliability. The mechanism of PD-LVI was demonstrated to be based on the column-head stacking effect with pre-column dilution. Based on the results, PD-LVI as a simple and effective sample injection technique of reverse phase UHPLC-MS/MS for the analysis of trace analytes in complex samples showed a great promising prospect. Copyright © 2016 Elsevier B.V. All rights reserved.

  12. Robotic Assisted Simple Prostatectomy versus Holmium Laser Enucleation of the Prostate for Lower Urinary Tract Symptoms in Patients with Large Volume Prostate: A Comparative Analysis from a High Volume Center.

    Science.gov (United States)

    Umari, Paolo; Fossati, Nicola; Gandaglia, Giorgio; Pokorny, Morgan; De Groote, Ruben; Geurts, Nicolas; Goossens, Marijn; Schatterman, Peter; De Naeyer, Geert; Mottrie, Alexandre

    2017-04-01

    We report a comparative analysis of robotic assisted simple prostatectomy vs holmium laser enucleation of the prostate in patients who had benign prostatic hyperplasia with a large volume prostate (greater than 100 ml). A total of 81 patients underwent robotic assisted simple prostatectomy and 45 underwent holmium laser enucleation of the prostate in a 7-year period. Patients were preoperatively assessed with transrectal ultrasound and uroflowmetry. Functional parameters were assessed postoperatively during followup. Perioperative outcomes included operative time, postoperative hemoglobin, catheterization time and hospitalization. Complications were reported according to the Clavien-Dindo classification. Compared to the holmium laser enucleation group, patients treated with prostatectomy were significantly younger (median age 69 vs 74 years, p = 0.032) and less healthy (Charlson comorbidity index 2 or greater in 62% vs 29%, p = 0.0003), and had a lower rate of suprapubic catheterization (23% vs 42%, p = 0.028) and a higher preoperative I-PSS (International Prostate Symptom Score) (25 vs 21, p = 0.049). Both groups showed an improvement in the maximum flow rate (15 vs 11 ml per second, p = 0.7), and a significant reduction in post-void residual urine (-73 vs -100 ml, p = 0.4) and I-PSS (-20 vs -18, p = 0.8). Median operative time (105 vs 105 minutes, p = 0.9) and postoperative hemoglobin (13.2 vs 13.8 gm/dl, p = 0.08) were similar for robotic assisted prostatectomy and holmium laser enucleation, respectively. Median catheterization time (3 vs 2 days, p = 0.005) and median hospitalization (4 vs 2 days, p = 0.0001) were slightly shorter in the holmium laser group. Complication rates were similar with no Clavien grade greater than 3 in either group. Our results from a single center suggest comparable outcomes for robotic assisted simple prostatectomy and holmium laser enucleation of the prostate in patients with a large volume prostate. These findings require

  13. AGN Populations in Large-volume X-Ray Surveys: Photometric Redshifts and Population Types Found in the Stripe 82X Survey

    Science.gov (United States)

    Ananna, Tonima Tasnin; Salvato, Mara; LaMassa, Stephanie; Urry, C. Megan; Cappelluti, Nico; Cardamone, Carolin; Civano, Francesca; Farrah, Duncan; Gilfanov, Marat; Glikman, Eilat; Hamilton, Mark; Kirkpatrick, Allison; Lanzuisi, Giorgio; Marchesi, Stefano; Merloni, Andrea; Nandra, Kirpal; Natarajan, Priyamvada; Richards, Gordon T.; Timlin, John

    2017-11-01

    Multiwavelength surveys covering large sky volumes are necessary to obtain an accurate census of rare objects such as high-luminosity and/or high-redshift active galactic nuclei (AGNs). Stripe 82X is a 31.3 X-ray survey with Chandra and XMM-Newton observations overlapping the legacy Sloan Digital Sky Survey Stripe 82 field, which has a rich investment of multiwavelength coverage from the ultraviolet to the radio. The wide-area nature of this survey presents new challenges for photometric redshifts for AGNs compared to previous work on narrow-deep fields because it probes different populations of objects that need to be identified and represented in the library of templates. Here we present an updated X-ray plus multiwavelength matched catalog, including Spitzer counterparts, and estimated photometric redshifts for 5961 (96% of a total of 6181) X-ray sources that have a normalized median absolute deviation, σnmad=0.06, and an outlier fraction, η = 13.7%. The populations found in this survey and the template libraries used for photometric redshifts provide important guiding principles for upcoming large-area surveys such as eROSITA and 3XMM (in X-ray) and the Large Synoptic Survey Telescope (optical).

  14. Highly selective solid-phase extraction and large volume injection for the robust gas chromatography-mass spectrometric analysis of TCA and TBA in wines.

    Science.gov (United States)

    Insa, S; Anticó, E; Ferreira, V

    2005-09-30

    A reliable solid-phase extraction (SPE) method for the simultaneous determination of 2,4,6-trichloroanisole (TCA) and 2,4,6-tribromoanisole (TBA) in wines has been developed. In the proposed procedure 50 mL of wine are extracted in a 1 mL cartridge filled with 50 mg of LiChrolut EN resins. Most wine volatiles are washed up with 12.5 mL of a water:methanol solution (70%, v/v) containing 1% of NaHCO3. Analytes are further eluted with 0.6 mL of dichloromethane. A 40 microL aliquot of this extract is directly injected into a PTV injector operated in the solvent split mode, and analysed by gas chromatography (GC)-ion trap mass spectrometry using the selected ion storage mode. The solid-phase extraction, including sample volume and rinsing and elution solvents, and the large volume GC injection have been carefully evaluated and optimized. The resulting method is precise (RSD (%) TBA, respectively), robust (the absolute recoveries of both analytes are higher than 80% and consistent wine to wine) and friendly to the GC-MS system (the extract is clean, simple and free from non-volatiles).

  15. Large-volume multi-tined expandable RF ablation in pig livers: comparison of 2D and volumetric measurements of the ablation zone

    International Nuclear Information System (INIS)

    Bangard, Christopher; Roesgen, Silvia; Lackner, Klaus J.; Wahba, Roger; Stippel, Dirk L.; Wiemker, Rafael; Hellmich, Martin; Reiter, Hannah; Fischer, Juergen H.

    2010-01-01

    To compare two-dimensional (2D) and three-dimensional (3D) computed tomography (CT) measurements of ablation zones (AZs) related to the shaft of two different large-volume monopolar multi-tined expandable electrodes. Percutaneous radiofrequency (RF) ablation was performed in 12 pigs (81.6±7.8 kg) using two electrodes (LeVeen 5 cm, Rita XL 5 cm; n=6 in each group). Contrast-enhanced CT with the electrode shaft in place evaluated the AZ. The largest sphere centred on the electrode shaft within the AZ was calculated (1) based on the 2D axial CT image in the plane of the shaft assuming rotational symmetry of the AZ and (2) using prototype software and the 3D volume data of the AZ measured with CT. The mean largest diameter of a sphere centred on the electrode shaft was always smaller using the 3D data of the AZ than using 2D CT measurements assuming rotational symmetry of the AZ (3D vs 2D): LeVeen 18.2±4.8 mm; 24.5 ±3.1 mm; p=0.001; Rita XL 20.0±3.7 mm; 28.8±4.9 mm; p=0.0002. All AZ showed indentations around the tines. Two-dimensional CT measurements assuming rotational symmetry of the AZ overestimate the largest ablated sphere centred on the electrode shaft compared with 3D CT measurements. (orig.)

  16. An evaluation on the design optimization of large capacity tanks in the chemical and volume control system for YGN 3 and 4

    International Nuclear Information System (INIS)

    Park, Byung Ho; Kim, Eun Ki; Ko, Deuk Yoon; Ko, Yong Sang; Kim, Seok Bum

    1996-06-01

    The design of Yonggwang nuclear power plant units 3 and 4 (YGN 3 and 4) is referenced to that of Palo Verde nuclear power plant (Palo Verde NPP) in Arizona, USA. The reactor vessel and steam generator of YGN 3 and 4 are smaller than that of Palo Verde NPP because Palo Verde NPP produces 1,300 Mw electricity, on the other hand, YGN 3 and 4 produces 1,000 Mw electricity. However, other components and systems of YGN 3 and 4 are the same as those of Palo verde NPP. The oversized system components may be considered to ensure the safety and operability by providing sufficient design margin, but it requires unnecessary cost burden to the owner of the plant. This report focuses on the optimization of the volume of the large tanks (i.e., above 400,000 gallons) in CVCS. These tanks are refueling water tank (RWT), reactor makeup water tank (RMWT) and holdup tank (HT). It has been performed that the calculation on the required tank volume based on design requirements, comparison on the calculation results with as-built design, and estimation on the instrumentation setpoint. 19 tabs., 12 figs., 13 refs. (Author)

  17. Radionuclides and particles in seawater with the large volume in situ filtration and concentration system in the coastal waters off Japan

    International Nuclear Information System (INIS)

    Aono, Tatsuo; Nakanishi, Takahiro; Okubo, Ayako; Zheng, Jian; Yamada, Masatoshi; Kusakabe, Masashi

    2008-01-01

    It is necessary to determine the radionuclides in dissolved and particulate state in order to clarify the distributions and behavior of these in seawater. Because the concentrations of radionuclides and particles are very low in the ocean, it is difficult to concentrate and fractionate the particulate matters with the filtration systems in seawater. The large volume in situ filtration and concentration system (LV-FiCS) was developed to collect various forms of trace radionuclides and particles in seawater. The LV-FiCS has been operated during several cruises in the coastal waters off Japan, and several m 3 of seawaters were filtered through different kinds of filters and then pass through the adsorbents to concentrate radionuclides simultaneously. This system could be shown the vertical profiles of thorium with the size-fractionated method and the behavior of these nuclides in the ocean. (author)

  18. Large-eddy simulations of 3D Taylor-Green vortex: comparison of Smoothed Particle Hydrodynamics, Lattice Boltzmann and Finite Volume methods

    International Nuclear Information System (INIS)

    Kajzer, A; Pozorski, J; Szewc, K

    2014-01-01

    In the paper we present Large-eddy simulation (LES) results of 3D Taylor- Green vortex obtained by the three different computational approaches: Smoothed Particle Hydrodynamics (SPH), Lattice Boltzmann Method (LBM) and Finite Volume Method (FVM). The Smagorinsky model was chosen as a subgrid-scale closure in LES for all considered methods and a selection of spatial resolutions have been investigated. The SPH and LBM computations have been carried out with the use of the in-house codes executed on GPU and compared, for validation purposes, with the FVM results obtained using the open-source CFD software OpenFOAM. A comparative study in terms of one-point statistics and turbulent energy spectra shows a good agreement of LES results for all methods. An analysis of the GPU code efficiency and implementation difficulties has been made. It is shown that both SPH and LBM may offer a significant advantage over mesh-based CFD methods.

  19. Analysis of polycyclic aromatic hydrocarbons in water and beverages using membrane-assisted solvent extraction in combination with large volume injection-gas chromatography-mass spectrometric detection.

    Science.gov (United States)

    Rodil, Rosario; Schellin, Manuela; Popp, Peter

    2007-09-07

    Membrane-assisted solvent extraction (MASE) in combination with large volume injection-gas chromatography-mass spectrometry (LVI-GC-MS) was applied for the determination of 16 polycyclic aromatic hydrocarbons (PAHs) in aqueous samples. The MASE conditions were optimized for achieving high enrichment of the analytes from aqueous samples, in terms of extraction conditions (shaking speed, extraction temperature and time), extraction solvent and composition (ionic strength, sample pH and presence of organic solvent). Parameters like linearity and reproducibility of the procedure were determined. The extraction efficiency was above 65% for all the analytes and the relative standard deviation (RSD) for five consecutive extractions ranged from 6 to 18%. At optimized conditions detection limits at the ng/L level were achieved. The effectiveness of the method was tested by analyzing real samples, such as river water, apple juice, red wine and milk.

  20. Large-volume constant-concentration sampling technique coupling with surface-enhanced Raman spectroscopy for rapid on-site gas analysis

    Science.gov (United States)

    Zhang, Zhuomin; Zhan, Yisen; Huang, Yichun; Li, Gongke

    2017-08-01

    In this work, a portable large-volume constant-concentration (LVCC) sampling technique coupling with surface-enhanced Raman spectroscopy (SERS) was developed for the rapid on-site gas analysis based on suitable derivatization methods. LVCC sampling technique mainly consisted of a specially designed sampling cell including the rigid sample container and flexible sampling bag, and an absorption-derivatization module with a portable pump and a gas flowmeter. LVCC sampling technique allowed large, alterable and well-controlled sampling volume, which kept the concentration of gas target in headspace phase constant during the entire sampling process and made the sampling result more representative. Moreover, absorption and derivatization of gas target during LVCC sampling process were efficiently merged in one step using bromine-thiourea and OPA-NH4+ strategy for ethylene and SO2 respectively, which made LVCC sampling technique conveniently adapted to consequent SERS analysis. Finally, a new LVCC sampling-SERS method was developed and successfully applied for rapid analysis of trace ethylene and SO2 from fruits. It was satisfied that trace ethylene and SO2 from real fruit samples could be actually and accurately quantified by this method. The minor concentration fluctuations of ethylene and SO2 during the entire LVCC sampling process were proved to be samples were achieved in range of 95.0-101% and 97.0-104% respectively. It is expected that portable LVCC sampling technique would pave the way for rapid on-site analysis of accurate concentrations of trace gas targets from real samples by SERS.

  1. The peak efficiency calibration of volume source using 152Eu point source in computer

    International Nuclear Information System (INIS)

    Shen Tingyun; Qian Jianfu; Nan Qinliang; Zhou Yanguo

    1997-01-01

    The author describes the method of the peak efficiency calibration of volume source by means of 152 Eu point source for HPGe γ spectrometer. The peak efficiency can be computed by Monte Carlo simulation, after inputting parameter of detector. The computation results are in agreement with the experimental results with an error of +-3.8%, with an exception one is about +-7.4%

  2. A propidium monoazide–quantitative PCR method for the detection and quantification of viable Enterococcus faecalis in large-volume samples of marine waters

    KAUST Repository

    Salam, Khaled W.; El-Fadel, Mutasem E.; Barbour, Elie K.; Saikaly, Pascal

    2014-01-01

    The development of rapid detection assays of cell viability is essential for monitoring the microbiological quality of water systems. Coupling propidium monoazide with quantitative PCR (PMA-qPCR) has been successfully applied in different studies for the detection and quantification of viable cells in small-volume samples (0.25-1.00 mL), but it has not been evaluated sufficiently in marine environments or in large-volume samples. In this study, we successfully integrated blue light-emitting diodes for photoactivating PMA and membrane filtration into the PMA-qPCR assay for the rapid detection and quantification of viable Enterococcus faecalis cells in 10-mL samples of marine waters. The assay was optimized in phosphate-buffered saline and seawater, reducing the qPCR signal of heat-killed E. faecalis cells by 4 log10 and 3 log10 units, respectively. Results suggest that high total dissolved solid concentration (32 g/L) in seawater can reduce PMA activity. Optimal PMA-qPCR standard curves with a 6-log dynamic range and detection limit of 102 cells/mL were generated for quantifying viable E. faecalis cells in marine waters. The developed assay was compared with the standard membrane filter (MF) method by quantifying viable E. faecalis cells in seawater samples exposed to solar radiation. The results of the developed PMA-qPCR assay did not match that of the standard MF method. This difference in the results reflects the different physiological states of E. faecalis cells in seawater. In conclusion, the developed assay is a rapid (∼5 h) method for the quantification of viable E. faecalis cells in marine recreational waters, which should be further improved and tested in different seawater settings. © 2014 Springer-Verlag Berlin Heidelberg.

  3. Investigation of the Relationship Between Gross Tumor Volume Location and Pneumonitis Rates Using a Large Clinical Database of Non-Small-Cell Lung Cancer Patients

    International Nuclear Information System (INIS)

    Vinogradskiy, Yevgeniy; Tucker, Susan L.; Liao Zhongxing; Martel, Mary K.

    2012-01-01

    Purpose: Studies have suggested that function may vary throughout the lung, and that patients who have tumors located in the base of the lung are more susceptible to radiation pneumonitis. The purpose of our study was to investigate the relationship between gross tumor volume (GTV) location and pneumonitis rates using a large clinical database of 547 patients with non–small-cell lung cancer. Methods and Materials: The GTV centroids of all patients were mapped onto one common coordinate system, in which the boundaries of the coordinate system were defined by the extreme points of each individual patient lung. The data were qualitatively analyzed by graphing all centroids and displaying the data according to the presence of severe pneumonitis, tumor stage, and smoking status. The centroids were grouped according to superior–inferior segments, and the pneumonitis rates were analyzed. In addition, we incorporated the GTV centroid information into a Lyman–Kutcher–Burman normal tissue complication probability model and tested whether adding spatial information significantly improved the fit of the model. Results: Of the 547 patients analyzed, 111 (20.3%) experienced severe radiation pneumonitis. The pneumonitis incidence rates were 16%, 23%, and 21% for the superior, middle, and inferior thirds of the lung, respectively. Qualitatively, the GTV centroids of nonsmokers were notably absent from the superior portion of the lung. In addition, the GTV centroids of patients who had Stage III and IV clinical staging were concentrated toward the medial edge of the lung. The comparison between the GTV centroid model and the conventional dose–volume model did not yield a statistically significant difference in model fit. Conclusions: Lower pneumonitis rates were noted for the superior portion of the lung; however the differences were not statistically significant. For our patient cohort, incorporating GTV centroid information did not lead to a statistically significant

  4. A propidium monoazide–quantitative PCR method for the detection and quantification of viable Enterococcus faecalis in large-volume samples of marine waters

    KAUST Repository

    Salam, Khaled W.

    2014-08-23

    The development of rapid detection assays of cell viability is essential for monitoring the microbiological quality of water systems. Coupling propidium monoazide with quantitative PCR (PMA-qPCR) has been successfully applied in different studies for the detection and quantification of viable cells in small-volume samples (0.25-1.00 mL), but it has not been evaluated sufficiently in marine environments or in large-volume samples. In this study, we successfully integrated blue light-emitting diodes for photoactivating PMA and membrane filtration into the PMA-qPCR assay for the rapid detection and quantification of viable Enterococcus faecalis cells in 10-mL samples of marine waters. The assay was optimized in phosphate-buffered saline and seawater, reducing the qPCR signal of heat-killed E. faecalis cells by 4 log10 and 3 log10 units, respectively. Results suggest that high total dissolved solid concentration (32 g/L) in seawater can reduce PMA activity. Optimal PMA-qPCR standard curves with a 6-log dynamic range and detection limit of 102 cells/mL were generated for quantifying viable E. faecalis cells in marine waters. The developed assay was compared with the standard membrane filter (MF) method by quantifying viable E. faecalis cells in seawater samples exposed to solar radiation. The results of the developed PMA-qPCR assay did not match that of the standard MF method. This difference in the results reflects the different physiological states of E. faecalis cells in seawater. In conclusion, the developed assay is a rapid (∼5 h) method for the quantification of viable E. faecalis cells in marine recreational waters, which should be further improved and tested in different seawater settings. © 2014 Springer-Verlag Berlin Heidelberg.

  5. Investigation of the relationship between gross tumor volume location and pneumonitis rates using a large clinical database of non-small-cell lung cancer patients.

    Science.gov (United States)

    Vinogradskiy, Yevgeniy; Tucker, Susan L; Liao, Zhongxing; Martel, Mary K

    2012-04-01

    Studies have suggested that function may vary throughout the lung, and that patients who have tumors located in the base of the lung are more susceptible to radiation pneumonitis. The purpose of our study was to investigate the relationship between gross tumor volume (GTV) location and pneumonitis rates using a large clinical database of 547 patients with non-small-cell lung cancer. The GTV centroids of all patients were mapped onto one common coordinate system, in which the boundaries of the coordinate system were defined by the extreme points of each individual patient lung. The data were qualitatively analyzed by graphing all centroids and displaying the data according to the presence of severe pneumonitis, tumor stage, and smoking status. The centroids were grouped according to superior-inferior segments, and the pneumonitis rates were analyzed. In addition, we incorporated the GTV centroid information into a Lyman-Kutcher-Burman normal tissue complication probability model and tested whether adding spatial information significantly improved the fit of the model. Of the 547 patients analyzed, 111 (20.3%) experienced severe radiation pneumonitis. The pneumonitis incidence rates were 16%, 23%, and 21% for the superior, middle, and inferior thirds of the lung, respectively. Qualitatively, the GTV centroids of nonsmokers were notably absent from the superior portion of the lung. In addition, the GTV centroids of patients who had Stage III and IV clinical staging were concentrated toward the medial edge of the lung. The comparison between the GTV centroid model and the conventional dose-volume model did not yield a statistically significant difference in model fit. Lower pneumonitis rates were noted for the superior portion of the lung; however the differences were not statistically significant. For our patient cohort, incorporating GTV centroid information did not lead to a statistically significant improvement in the fit of the pneumonitis model. Copyright

  6. A dosimetric comparison of 3D-CRT, IMRT, and static tomotherapy with an SIB for large and small breast volumes

    Energy Technology Data Exchange (ETDEWEB)

    Michalski, Andrea [Department of Health Science (MRS), The University of Sydney, Lidcombe, New South Wales (Australia); Central Coast Cancer Centre, Gosford Hospital, Gosford, New South Wales (Australia); Atyeo, John, E-mail: john.atyeo@sydney.edu.au [Department of Health Science (MRS), The University of Sydney, Lidcombe, New South Wales (Australia); Cox, Jennifer [Department of Health Science (MRS), The University of Sydney, Lidcombe, New South Wales (Australia); Department of Radiation Oncology, Royal North Shore Hospital, St Leonards, New South Wales (Australia); Rinks, Marianne [Department of Health Science (MRS), The University of Sydney, Lidcombe, New South Wales (Australia); Radiation Oncology, Cancer Services, Illawarra Shoalhaven Local Health District, Wollongong, New South Wales (Australia); Morgia, Marita; Lamoury, Gillian [Department of Radiation Oncology, Royal North Shore Hospital, St Leonards, New South Wales (Australia)

    2014-07-01

    Radiation therapy to the breast is a complex task, with many different techniques that can be employed to ensure adequate dose target coverage while minimizing doses to the organs at risk. This study compares the dose planning outcomes of 3 radiation treatment modalities, 3 dimensional conformal radiation therapy (3D-CRT), intensity-modulated radiation therapy (IMRT), and static tomotherapy, for left-sided whole-breast radiation treatment with a simultaneous integrated boost (SIB). Overall, 20 patients with left-sided breast cancer were separated into 2 cohorts, small and large, based on breast volume. Dose plans were produced for each patient using 3D-CRT, IMRT, and static tomotherapy. All patients were prescribed a dose of 45 Gy in 20 fractions to the breast with an SIB of 56 Gy in 20 fractions to the tumor bed and normalized so that D{sub 98%} > 95% of the prescription dose. Dosimetric comparisons were made between the 3 modalities and the interaction of patient size. All 3 modalities offered adequate planning target volume (PTV) coverage with D{sub 98%} > 95% and D{sub 2%} < 107%. Static tomotherapy offered significantly improved (p = 0.006) dose homogeneity to the PTV{sub boost} {sub eval} (0.079 ± 0.011) and breast minus the SIB volume (Breast{sub SIB}) (p < 0.001, 0.15 ± 0.03) compared with the PTV{sub boost} {sub eval} (0.085 ± 0.008, 0.088 ± 0.12) and Breast{sub SIB} (0.22 ± 0.05, 0.23 ± 0.03) for IMRT and 3D-CRT, respectively. Static tomotherapy also offered statistically significant reductions (p < 0.001) in doses to the ipsilateral lung mean dose of 6.79 ± 2.11 Gy compared with 7.75 ± 2.54 Gy and 8.29 ± 2.76 Gy for IMRT and 3D-CRT, respectively, and significantly (p < 0.001) reduced heart doses (mean = 2.83 ± 1.26 Gy) compared to both IMRT and 3D-CRT (mean = 3.70 ± 1.44 Gy and 3.91 ± 1.58 Gy). Static tomotherapy is the dosimetrically superior modality for the whole breast with an SIB compared with IMRT and 3D-CRT. IMRT is superior to 3D

  7. Open Data, Jupyter Notebooks and Geospatial Data Standards Combined - Opening up large volumes of marine and climate data to other communities

    Science.gov (United States)

    Clements, O.; Siemen, S.; Wagemann, J.

    2017-12-01

    The EU-funded Earthserver-2 project aims to offer on-demand access to large volumes of environmental data (Earth Observation, Marine, Climate data and Planetary data) via the interface standard Web Coverage Service defined by the Open Geospatial Consortium. Providing access to data via OGC web services (e.g. WCS and WMS) has the potential to open up services to a wider audience, especially to users outside the respective communities. Especially WCS 2.0 with its processing extension Web Coverage Processing Service (WCPS) is highly beneficial to make large volumes accessible to non-expert communities. Users do not have to deal with custom community data formats, such as GRIB for the meteorological community, but can directly access the data in a format they are more familiar with, such as NetCDF, JSON or CSV. Data requests can further directly be integrated into custom processing routines and users are not required to download Gigabytes of data anymore. WCS supports trim (reduction of data extent) and slice (reduction of data dimension) operations on multi-dimensional data, providing users a very flexible on-demand access to the data. WCPS allows the user to craft queries to run on the data using a text-based query language, similar to SQL. These queries can be very powerful, e.g. condensing a three-dimensional data cube into its two-dimensional mean. However, the more processing-intensive the more complex the query. As part of the EarthServer-2 project, we developed a python library that helps users to generate complex WCPS queries with Python, a programming language they are more familiar with. The interactive presentation aims to give practical examples how users can benefit from two specific WCS services from the Marine and Climate community. Use-cases from the two communities will show different approaches to take advantage of a Web Coverage (Processing) Service. The entire content is available with Jupyter Notebooks, as they prove to be a highly beneficial tool

  8. Towards large volume big divisor D3/D7 " μ-split supersymmetry" and Ricci-flat Swiss-cheese metrics, and dimension-six neutrino mass operators

    Science.gov (United States)

    Dhuria, Mansi; Misra, Aalok

    2012-02-01

    We show that it is possible to realize a " μ-split SUSY" scenario (Cheng and Cheng, 2005) [1] in the context of large volume limit of type IIB compactifications on Swiss-cheese Calabi-Yau orientifolds in the presence of a mobile space-time filling D3-brane and a (stack of) D7-brane(s) wrapping the "big" divisor. For this, we investigate the possibility of getting one Higgs to be light while other to be heavy in addition to a heavy higgsino mass parameter. Further, we examine the existence of long lived gluino that manifests one of the major consequences of μ-split SUSY scenario, by computing its decay width as well as lifetime corresponding to the three-body decays of the gluino into either a quark, a squark and a neutralino or a quark, squark and goldstino, as well as two-body decays of the gluino into either a neutralino and a gluon or a goldstino and a gluon. Guided by the geometric Kähler potential for Σ obtained in Misra and Shukla (2010) [2] based on GLSM techniques, and the Donaldson's algorithm (Barun et al., 2008) [3] for obtaining numerically a Ricci-flat metric, we give details of our calculation in Misra and Shukla (2011) [4] pertaining to our proposed metric for the full Swiss-cheese Calabi-Yau (the geometric Kähler potential being needed to be included in the full moduli space Kähler potential in the presence of the mobile space-time filling D3-brane), but for simplicity of calculation, close to the big divisor, which is Ricci-flat in the large volume limit. Also, as an application of the one-loop RG flow solution for the higgsino mass parameter, we show that the contribution to the neutrino masses at the EW scale from dimension-six operators arising from the Kähler potential, is suppressed relative to the Weinberg-type dimension-five operators.

  9. A measurement of the efficiency for the detection of neutrons in the momentum range 200 to 3200 MeV/c, in large volume liquid scintillation counters

    International Nuclear Information System (INIS)

    Brown, R.M.; Clark, A.G.; Duke, P.J.

    1976-04-01

    A description is given of a system of 194 large volume liquid scintillation counters designed to detect neutrons in an experiment on the reaction π - p → π 0 n in the resonance region. The detection efficiency of the system has been determined, as a function of neutron momentum, in three separate measurements, covering the range 200 to 3200 MeV/c. Below 400 MeV/c the efficiency shows the expected momentum dependence near threshold, rising to a maximum of 50% near 300 MeV/c and then falling to 43% near 400 MeV/c. In the region 400 to 700 MeV/c the efficiency rises to 47% near 600 MeV/c and falls again to 43%, an effect not seen before; the efficiency was expected to be almost momentum independent in this region. Above the threshold for inelastic processes in nucleon-nucleon collision (approximately 800 MeV/c) the efficiency rises significantly reaching a maximum value of 65% above 1700 MeV/c. (author)

  10. Determination of tributyltin in environmental water matrices using stir bar sorptive extraction with in-situ derivatisation and large volume injection-gas chromatography-mass spectrometry.

    Science.gov (United States)

    Neng, N R; Santalla, R P; Nogueira, J M F

    2014-08-01

    Stir bar sorptive extraction with in-situ derivatization using sodium tetrahydridoborate (NaBH4) followed by liquid desorption and large volume injection-gas chromatography-mass spectrometry detection under the selected ion monitoring mode (SBSE(NaBH4)in-situ-LD/LVI-GC-MS(SIM)) was successfully developed for the determination of tributyltin (TBT) in environmental water matrices. NaBH4 proved to be an effective and easy in-situ speciation agent for TBT in aqueous media, allowing the formation of adducts with enough stability and suitable polarity for SBSE analysis. Assays performed on water samples spiked at the 10.0μg/L, yielded convenient recoveries (68.2±3.0%), showed good accuracy, suitable precision (RSD<9.0%), low detection limits (23ng/L) and excellent linear dynamic range (r(2)=0.9999) from 0.1 to 170.0µg/L, under optimized experimental conditions. By using the standard addition method, the application of the present methodology to real surface water samples allowed very good performance at the trace level. The proposed methodology proved to be a feasible alternative for routine quality control analysis, easy to implement, reliable and sensitive to monitor TBT in environmental water matrices. Copyright © 2014 Elsevier B.V. All rights reserved.

  11. High-sensitivity direct analysis of aflatoxins in peanuts and cereal matrices by ultra-performance liquid chromatography with fluorescence detection involving a large volume flow cell.

    Science.gov (United States)

    Oulkar, Dasharath; Goon, Arnab; Dhanshetty, Manisha; Khan, Zareen; Satav, Sagar; Banerjee, Kaushik

    2018-04-03

    This paper reports a sensitive and cost effective method of analysis for aflatoxins B1, B2, G1 and G2. The sample preparation method was primarily optimised in peanuts, followed by its validation in a range of peanut-processed products and cereal (rice, corn, millets) matrices. Peanut slurry [12.5 g peanut + 12.5 mL water] was extracted with methanol: water (8:2, 100 mL), cleaned through an immunoaffinity column and thereafter measured directly by ultra-performance liquid chromatography-fluorescence (UPLC-FLD) detection, within a chromatographic runtime of 5 minutes. The use of a large volume flow cell in the FLD nullified the requirement of any post-column derivatisation and provided the lowest ever reported limits of quantification of 0.025 for B1 and G1 and 0.01 μg/kg for B2 and G2. The single laboratory validation of the method provided acceptable selectivity, linearity, recovery and precision for reliable quantifications in all the test matrices as well as demonstrated compliance with the EC 401/2006 guidelines for analytical quality control of aflatoxins in foodstuffs.

  12. The design and performance of a large-volume spherical CsI(Tl) scintillation counter for gamma-ray spectroscopy

    CERN Document Server

    Meng, L J; Chirkin, V M; Potapov, V N; Ivanov, O P; Ignatov, S M

    2002-01-01

    This paper presents details of the design and performance of a prototype large-volume scintillation detector used for gamma-ray spectroscopy. In this detector, a spherical CsI(Tl) scintillation crystal having a diameter of 5.7 cm was polished and packed in dry MgO powder. The scintillation light from the crystal was viewed using a single 1x1 cm sup 2 silicon PIN diode. A low-noise preamplifier was also integrated within the detector housing. The measured noise level was equivalent to approx 800 electrons (FWHM). Such a configuration provided a very good light collection efficiency, which resulted in an average of 20 electrons being generated per keV of energy deposited in the crystal. One of the key features of the detector design is that it minimises spatial variations in the light collection efficiency throughout the detector. Compared with a standard 3 in. NaI scintillation counter, this feature leads to a much-improved energy resolution, particularly for photon energies above 1 MeV. The results presented ...

  13. Water pollution screening by large-volume injection of aqueous samples and application to GC/MS analysis of a river Elbe sample

    Energy Technology Data Exchange (ETDEWEB)

    Mueller, S.; Efer, J.; Engewald, W. [Leipzig Univ. (Germany). Inst. fuer Analytische Chemie

    1997-03-01

    The large-volume sampling of aqueous samples in a programmed temperature vaporizer (PTV) injector was used successfully for the target and non-target analysis of real samples. In this still rarely applied method, e.g., 1 mL of the water sample to be analyzed is slowly injected direct into the PTV. The vaporized water is eliminated through the split vent. The analytes are concentrated onto an adsorbent inside the insert and subsequently thermally desorbed. The capability of the method is demonstrated using a sample from the river Elbe. By means of coupling this method with a mass selective detector in SIM mode (target analysis) the method allows the determination of pollutants in the concentration range up to 0.01 {mu}g/L. Furthermore, PTV enrichment is an effective and time-saving method for non-target analysis in SCAN mode. In a sample from the river Elbe over 20 compounds were identified. (orig.) With 3 figs., 2 tabs.

  14. Towards Large Volume Big Divisor D3-D7 "mu-Split Supersymmetry" and Ricci-Flat Swiss-Cheese Metrics, and Dimension-Six Neutrino Mass Operators

    CERN Document Server

    Dhuria, Mansi

    2012-01-01

    We show that it is possible to realize a "mu-split SUSY" scenario [1] in the context of large volume limit of type IIB compactifications on Swiss-Cheese Calabi-Yau's in the presence of a mobile space-time filling D3-brane and a (stack of) D7-brane(s) wrapping the "big" divisor Sigma_B. For this, we investigate the possibility of getting one Higgs to be light while other to be heavy in addition to a heavy Higgsino mass parameter. Further, we examine the existence of long lived gluino that manifests one of the major consequences of mu-split SUSY scenario, by computing its decay width as well as lifetime corresponding to the 3-body decays of the gluino into a quark, a squark and a neutralino or Goldstino, as well as 2-body decays of the gluino into either a neutralino or a Goldstino and a gluon. Guided by the geometric Kaehler potential for Sigma_B obtained in [2] based on GLSM techniques, and the Donaldson's algorithm [3] for obtaining numerically a Ricci-flat metric, we give details of our calculation in [4] p...

  15. Improvement of the Ca determination accuracy with k (0)-INAA using an HPGe coaxial detector with extended energy range efficiency calibration

    Czech Academy of Sciences Publication Activity Database

    Kučera, Jan; Kubešová, Marie; Lebeda, Ondřej

    2018-01-01

    Roč. 315, č. 3 (2018), s. 671-675 ISSN 0236-5731. [7th International K0-Users Workshop. Montreal, 03.09.2017-08.09.2017] R&D Projects: GA ČR(CZ) GBP108/12/G108; GA MŠk LM2015056 Institutional support: RVO:61389005 Keywords : k(0)-INAA * Ca determination * HPGe detector * High-energy efficiency calibration * Co-56 activity standard Subject RIV: CB - Analytical Chemistry, Separation OBOR OECD: Analytical chemistry Impact factor: 1.282, year: 2016

  16. Surface Alpha Interactions in P-Type Point-Contact HPGe Detectors: Maximizing Sensitivity of 76Ge Neutrinoless Double-Beta Decay Searches

    Science.gov (United States)

    Gruszko, Julieta

    Though the existence of neutrino oscillations proves that neutrinos must have non-zero mass, Beyond-the-Standard-Model physics is needed to explain the origins of that mass. One intriguing possibility is that neutrinos are Majorana particles, i.e., they are their own anti-particles. Such a mechanism could naturally explain the observed smallness of the neutrino masses, and would have consequences that go far beyond neutrino physics, with implications for Grand Unification and leptogenesis. If neutrinos are Majorana particles, they could undergo neutrinoless double-beta decay (0nBB), a hypothesized rare decay in which two antineutrinos annihilate one another. This process, if it exists, would be exceedingly rare, with a half-life over 1E25 years. Therefore, searching for it requires experiments with extremely low background rates. One promising technique in the search for 0nBB is the use of P-type point-contact (P-PC) high-purity Germanium (HPGe) detectors enriched in 76Ge, operated in large low-background arrays. This approach is used, with some key differences, by the MAJORANA and GERDA Collaborations. A problematic background in such large granular detector arrays is posed by alpha particles incident on the surfaces of the detectors, often caused by 222Rn contamination of parts or of the detectors themselves. In the MAJORANA DEMONSTRATOR, events have been observed that are consistent with energy-degraded alphas originating near the passivated surface of the detectors, leading to a potential background contribution in the region-of-interest for neutrinoless double-beta decay. However, it is also observed that when energy deposition occurs very close to the passivated surface, high charge trapping occurs along with subsequent slow charge re-release. This leads to both a reduced prompt signal and a measurable change in slope of the tail of a recorded pulse. Here we discuss the characteristics of these events and the development of a filter that can identify the

  17. Quantitative method of viral pollution determination for large volume of water using ferric hydroxide gel impregnated on the surface of glassfibre cartridge

    Directory of Open Access Journals (Sweden)

    Akira Homma

    1974-01-01

    Full Text Available Quantitative method of viral pollution determination for large volume of water using ferric hydroxide gel impregnated on the surface of glassfibre cartridge filter. The use of ferric hydroxide gel, impregnated on the surface of glassfibre cartridge filter enable us to recover 62.5% of virus (Poliomylitis type I, Lsc strain exsogeneously added to 400 liters of tap-water. The virus concentrator system consists of four cartridge filters, in which the three first one are clarifiers, where the contaminants are removed physically, without significant virus loss at this stage. The last cartridge filter is impregnated with ferric hydroxide gel, where the virus is adsorbed. After the required volume of water has been processed, the last filter is removed from the system and the viruses are recovered from the gel, using 1 liter of glycine/NaOH buffer, at pH 11. Immediately the eluate is clarified through series of cellulose acetate membranes mounted in a 142mm Millipore filter. For the second step of virus concentration, HC1 1N is added slowly to the eluate to achieve pH 3.5-4. MgC1, is added to give a final concentration of 0.05M and the viruses are readsorbed on a 0.45 , porosity (HA cellulose acetate membrane, mounted in a 90 mm Millipore filter. The viruses are recovered using the same eluent plus 10% of fetal calf serum, to a final volume of 3 ml. In this way, it was possible to concentrate virus from 400 liters of tap-water, into 1 liter in the first stage of virus concentration and just to 3 ml of final volume in a second step. The efficiency, simplicity and low operational cost, provded by the method, make it feasible to study viral pollution of recreational and tap-water sources.Relata-se o emprego de um concentrador portátil, o qual se mostrou capaz de recuperar 62,5% dos vírus (Polio I, amostra Lsc experimentalmente dispersos em 400 litros de água, os quais foram reduzidos a 3 ml. O sistema concentrador de vírus é composto de quatro

  18. The prognostic value of baseline {sup 18}F-FDG PET/CT in steroid-naive large-vessel vasculitis: introduction of volume-based parameters

    Energy Technology Data Exchange (ETDEWEB)

    Dellavedova, L. [Ospedale Civile di Legnano, PET/CT Center - Nuclear Medicine Department, Legnano (Italy); University of Milan, Department of Health Sciences, Milan (Italy); Carletto, M.; Maffioli, L.S. [Ospedale Civile di Legnano, PET/CT Center - Nuclear Medicine Department, Legnano (Italy); Faggioli, P.; Sciascera, A.; Mazzone, A. [Ospedale Civile di Legnano, Internal Medicine Department, Legnano (Italy); Del Sole, A. [University of Milan, Department of Health Sciences, Milan (Italy)

    2016-02-15

    The aim of this study was to analyse if the result of a baseline {sup 18}F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT scan, in large-vessel vasculitis (LVV) patients, is able to predict the course of the disease, not only in terms of presence/absence of final complications but also in terms of favourable/complicated progress (response to steroid therapy, time to steroid suspension, relapses, etc.). A total of 46 consecutive patients, who underwent {sup 18}F-FDG PET/CT between May 2010 and March 2013 for fever of unknown origin (FUO) or suspected vasculitis (before starting corticosteroid therapy), were enrolled. The diagnosis of LVV was confirmed in 17 patients. Considering follow-up results, positive LVV patients were divided into two groups, one characterized by favourable (nine) and the other by complicated progress (eight), on the basis of presence/absence of vascular complications, presence/absence of at least another positive PET/CT during follow-up and impossibility to comply with the tapering schedule of the steroid due to biochemical/symptomatic relapse. Vessel uptake in subjects of the two groups was compared in terms of intensity and extension. To evaluate the extent of active disease, we introduced two volume-based parameters: ''volume of increased uptake'' (VIU) and ''total lesion glycolysis'' (TLG). The threshold used to calculate VIU on vessel walls was obtained by the ''vessel to liver'' ratio by means of receiver-operating characteristic analysis and was set at 0.92 x liver maximum standardized uptake value in each patient. Measures of tracer uptake intensity were significantly higher in patients with complicated progress compared to those with a favourable one (p < 0.05). Measures of disease extension were even more significant and TLG emerged as the best parameter to separate the two groups of patients (p = 0.01). This pilot study shows that, in LVV patients, the

  19. The prognostic value of baseline 18F-FDG PET/CT in steroid-naive large-vessel vasculitis: introduction of volume-based parameters

    International Nuclear Information System (INIS)

    Dellavedova, L.; Carletto, M.; Maffioli, L.S.; Faggioli, P.; Sciascera, A.; Mazzone, A.; Del Sole, A.

    2016-01-01

    The aim of this study was to analyse if the result of a baseline 18 F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT scan, in large-vessel vasculitis (LVV) patients, is able to predict the course of the disease, not only in terms of presence/absence of final complications but also in terms of favourable/complicated progress (response to steroid therapy, time to steroid suspension, relapses, etc.). A total of 46 consecutive patients, who underwent 18 F-FDG PET/CT between May 2010 and March 2013 for fever of unknown origin (FUO) or suspected vasculitis (before starting corticosteroid therapy), were enrolled. The diagnosis of LVV was confirmed in 17 patients. Considering follow-up results, positive LVV patients were divided into two groups, one characterized by favourable (nine) and the other by complicated progress (eight), on the basis of presence/absence of vascular complications, presence/absence of at least another positive PET/CT during follow-up and impossibility to comply with the tapering schedule of the steroid due to biochemical/symptomatic relapse. Vessel uptake in subjects of the two groups was compared in terms of intensity and extension. To evaluate the extent of active disease, we introduced two volume-based parameters: ''volume of increased uptake'' (VIU) and ''total lesion glycolysis'' (TLG). The threshold used to calculate VIU on vessel walls was obtained by the ''vessel to liver'' ratio by means of receiver-operating characteristic analysis and was set at 0.92 x liver maximum standardized uptake value in each patient. Measures of tracer uptake intensity were significantly higher in patients with complicated progress compared to those with a favourable one (p < 0.05). Measures of disease extension were even more significant and TLG emerged as the best parameter to separate the two groups of patients (p = 0.01). This pilot study shows that, in LVV patients, the combined

  20. The determination of acrylamide in environmental and drinking waters by large-volume injection - hydrophilic-interaction liquid chromatography and tandem mass spectrometry.

    Science.gov (United States)

    Backe, Will J; Yingling, Virginia; Johnson, Todd

    2014-03-21

    A simple and sensitive analytical method was developed to quantify levels of acrylamide in environmental and drinking waters. The analytical method consisted of solvent exchanging acrylamide from 2mL of water into 2mL of dichloromethane using acetonitrile as an intermediate. The sample was then directly analyzed by large-volume (750μL) injection - hydrophilic-interaction liquid chromatography and tandem mass spectrometry. The method detection limit and reporting level were 2.4ng/L and 17ng/L of acrylamide, respectively. The recovery of acrylamide during solvent exchange was 95±2.8% and the matrix effects were 12±2.2% in river water. The use of atmospheric-pressure chemical ionization reduced matrix effects; however, it also reduced method sensitivity by a factor of 2.2 compared to electrospray ionization. Matrix effects were compensated for by the use of an isotopically-labeled internal standard and the method accuracy was 89±3.0% at 25ng/L of acrylamide and 102±2.6% at 250ng/L of acrylamide. The precision of the method was less than 6% relative standard deviation at both 25ng/L and 250ng/L of acrylamide. Samples from a sand-and-gravel mine and a drinking-water treatment plant were acquired to demonstrate the method. The concentrations of acrylamide at the sand-and-gravel mine were up to 280ng/L. In the drinking-water treatment plant, the concentration of acrylamide was approximately double in the finished drinking water when compared to other stages in the drinking-water treatment process. Disinfection or fluoridation may result in higher concentrations of acrylamide in finished drinking water; however, further research in this area is necessary. Copyright © 2014 Elsevier B.V. All rights reserved.

  1. Use of Raman Spectroscopy and Delta Volume Growth from Void Collapse to Assess Overwrap Stress Gradients Compromising the Reliability of Large Kevlar/Epoxy COPVs

    Science.gov (United States)

    Kezirian, Michael T.; Phoenix, S. Leigh; Eldridge, Jeffrey I.

    2009-01-01

    Composite Overwrapped Pressure Vessels (COPVs) are frequently used for storing pressurized gases aboard spacecraft and aircraft when weight saving is desirable compared to all-metal versions. Failure mechanisms in fibrous COPVs and variability in lifetime can be very different from their metallic counterparts; in the former, catastrophic stress-rupture can occur with virtually no warning, whereas in latter, a leak before burst design philosophy can be implemented. Qualification and certification typically requires only one burst test on a production sample (possibly after several pressure cycles) and the vessel need only meet a design burst strength (the maximum operating pressure divided by a knockdown factor). Typically there is no requirement to assess variability in burst strength or lifetime, much less determine production and materials processing parameters important to control of such variability. Characterizing such variability and its source is crucial to models for calculating required reliability over a given lifetime (e.g. R = 0.9999 for 15 years). In this paper we present a case study of how lack of control of certain process parameters in COPV manufacturing can result in variations among vessels and between production runs that can greatly increase uncertainty and reduce reliability. The vessels considered are 40-inch ( NASA Glenn Research center, Cleveland, OH, 44135 29,500 in3 ) spherical COPVs with a 0.74 in. thick Kevlar49/epoxy overwrap and with a titanium liner of which 34 were originally produced. Two burst tests were eventually performed that unexpectedly differed by almost 5%, and were 10% lower than anticipated from burst tests on 26-inch sister vessels similar in every detail. A major observation from measurements made during proof testing (autofrettage) of the 40-inch vessels was that permanent volume growth from liner yielding varied by a factor of more than two (150 in3 to 360 in3 ), which suggests large differences in the residual

  2. Automated high-volume aerosol sampling station for environmental radiation monitoring

    International Nuclear Information System (INIS)

    Toivonen, H.; Honkamaa, T.; Ilander, T.; Leppaenen, A.; Nikkinen, M.; Poellaenen, R.; Ylaetalo, S.

    1998-07-01

    An automated high-volume aerosol sampling station, known as CINDERELLA.STUK, for environmental radiation monitoring has been developed by the Radiation and Nuclear Safety Authority (STUK), Finland. The sample is collected on a glass fibre filter (attached into a cassette), the airflow through the filter is 800 m 3 /h at maximum. During the sampling, the filter is continuously monitored with Na(I) scintillation detectors. After the sampling, the large filter is automatically cut into 15 pieces that form a small sample and after ageing, the pile of filter pieces is moved onto an HPGe detector. These actions are performed automatically by a robot. The system is operated at a duty cycle of 1 d sampling, 1 d decay and 1 d counting. Minimum detectable concentrations of radionuclides in air are typically 1Ae10 x 10 -6 Bq/m 3 . The station is equipped with various sensors to reveal unauthorized admittance. These sensors can be monitored remotely in real time via Internet or telephone lines. The processes and operation of the station are monitored and partly controlled by computer. The present approach fulfils the requirements of CTBTO for aerosol monitoring. The concept suits well for nuclear material safeguards, too

  3. Hippocampal volume is positively associated with behavioural inhibition (BIS) in a large community-based sample of mid-life adults: the PATH through life study.

    Science.gov (United States)

    Cherbuin, Nicolas; Windsor, Tim D; Anstey, Kaarin J; Maller, Jerome J; Meslin, Chantal; Sachdev, Perminder S

    2008-09-01

    The fields of personality research and neuropsychology have developed with very little overlap. Gray and McNaughton were among the first to recognize that personality traits must have neurobiological correlates and developed models relating personality factors to brain structures. Of particular note was their description of associations between conditioning, inhibition and activation of behaviours, and specific neural structures such as the hippocampus, amygdala and the prefrontal cortex. The aim of this study was to determine whether personality constructs representing the behavioural inhibition and activation systems (BIS/BAS) were associated with volumetric measures of the hippocampus and amygdala in humans. Amygdalar and hippocampal volumes were measured in 430 brain scans of cognitively intact community-based volunteers. Linear associations between brain volumes and the BIS/BAS measures were assessed using multiple regression, controlling for age, sex, education, intra-cranial and total brain volume. Results showed that hippocampal volumes were positively associated with BIS sensitivity and to a lesser extent with BAS sensitivity. No association was found between amygdalar volume and either the BIS or BAS. These findings add support to the model of Gray and McNaughton, which proposes a role of the hippocampus in the regulation of defensive/approach behaviours and trait anxiety but suggest an absence of associations between amygdala volume and BIS/BAS measures.

  4. A system for accurate and automated injection of hyperpolarized substrate with minimal dead time and scalable volumes over a large range

    Science.gov (United States)

    Reynolds, Steven; Bucur, Adriana; Port, Michael; Alizadeh, Tooba; Kazan, Samira M.; Tozer, Gillian M.; Paley, Martyn N. J.

    2014-02-01

    Over recent years hyperpolarization by dissolution dynamic nuclear polarization has become an established technique for studying metabolism in vivo in animal models. Temporal signal plots obtained from the injected metabolite and daughter products, e.g. pyruvate and lactate, can be fitted to compartmental models to estimate kinetic rate constants. Modeling and physiological parameter estimation can be made more robust by consistent and reproducible injections through automation. An injection system previously developed by us was limited in the injectable volume to between 0.6 and 2.4 ml and injection was delayed due to a required syringe filling step. An improved MR-compatible injector system has been developed that measures the pH of injected substrate, uses flow control to reduce dead volume within the injection cannula and can be operated over a larger volume range. The delay time to injection has been minimized by removing the syringe filling step by use of a peristaltic pump. For 100 μl to 10.000 ml, the volume range typically used for mice to rabbits, the average delivered volume was 97.8% of the demand volume. The standard deviation of delivered volumes was 7 μl for 100 μl and 20 μl for 10.000 ml demand volumes (mean S.D. was 9 ul in this range). In three repeat injections through a fixed 0.96 mm O.D. tube the coefficient of variation for the area under the curve was 2%. For in vivo injections of hyperpolarized pyruvate in tumor-bearing rats, signal was first detected in the input femoral vein cannula at 3-4 s post-injection trigger signal and at 9-12 s in tumor tissue. The pH of the injected pyruvate was 7.1 ± 0.3 (mean ± S.D., n = 10). For small injection volumes, e.g. less than 100 μl, the internal diameter of the tubing contained within the peristaltic pump could be reduced to improve accuracy. Larger injection volumes are limited only by the size of the receiving vessel connected to the pump.

  5. Developing a semi/automated protocol to post-process large volume, High-resolution airborne thermal infrared (TIR) imagery for urban waste heat mapping

    Science.gov (United States)

    Rahman, Mir Mustafizur

    In collaboration with The City of Calgary 2011 Sustainability Direction and as part of the HEAT (Heat Energy Assessment Technologies) project, the focus of this research is to develop a semi/automated 'protocol' to post-process large volumes of high-resolution (H-res) airborne thermal infrared (TIR) imagery to enable accurate urban waste heat mapping. HEAT is a free GeoWeb service, designed to help Calgary residents improve their home energy efficiency by visualizing the amount and location of waste heat leaving their homes and communities, as easily as clicking on their house in Google Maps. HEAT metrics are derived from 43 flight lines of TABI-1800 (Thermal Airborne Broadband Imager) data acquired on May 13--14, 2012 at night (11:00 pm--5:00 am) over The City of Calgary, Alberta (˜825 km 2) at a 50 cm spatial resolution and 0.05°C thermal resolution. At present, the only way to generate a large area, high-spatial resolution TIR scene is to acquire separate airborne flight lines and mosaic them together. However, the ambient sensed temperature within, and between flight lines naturally changes during acquisition (due to varying atmospheric and local micro-climate conditions), resulting in mosaicked images with different temperatures for the same scene components (e.g. roads, buildings), and mosaic join-lines arbitrarily bisect many thousands of homes. In combination these effects result in reduced utility and classification accuracy including, poorly defined HEAT Metrics, inaccurate hotspot detection and raw imagery that are difficult to interpret. In an effort to minimize these effects, three new semi/automated post-processing algorithms (the protocol) are described, which are then used to generate a 43 flight line mosaic of TABI-1800 data from which accurate Calgary waste heat maps and HEAT metrics can be generated. These algorithms (presented as four peer-reviewed papers)---are: (a) Thermal Urban Road Normalization (TURN)---used to mitigate the microclimatic

  6. Association between hospital procedure volume and early complications after pacemaker implantation: results from a large, unselected, contemporary cohort of the German nationwide obligatory external quality assurance programme.

    Science.gov (United States)

    Nowak, Bernd; Tasche, Karl; Barnewold, Linda; Heller, Günther; Schmidt, Boris; Bordignon, Stefano; Chun, K R Julian; Fürnkranz, Alexander; Mehta, Rajendra H

    2015-05-01

    Several studies demonstrated an inverse relationship between cardioverter-defibrillator implantation volume and complication rates, suggesting better outcomes for higher volume centres. However, the association of institutional procedural volume with patient outcomes for permanent pacemaker (PPM) implantation remains less known, especially in decentralized implantation systems. We performed retrospective examination of data on patients undergoing PPM from the German obligatory quality assurance programme (2007-12) to evaluate the relationship of hospital PPM volume (categorized into quintiles of their mean annual volume) with risk-adjusted in-hospital surgical complications (composite of pneumothorax, haemothorax, pericardial effusion, or pocket haematoma, all requiring intervention, or device infection) and pacemaker lead dislocation. Overall 430 416 PPM implantations were documented in 1226 hospitals. Systems included dual (72.8%) and single (25.8%) chamber PPM and cardiac resynchronization therapy (CRT) devices (1.1%). Complications included surgical (0.92%), and ventricular (0.99%), and atrial (1.22%) lead dislocation. Despite an increase in relatively complex procedures (dual chamber, CRT), there was a significant decrease in the procedural and fluoroscopy times and complications from lowest to highest implantation volume quintiles (P for trend <0.0001). The greatest difference was observed between the lowest (1-50 implantations/year-reference group) and the second-lowest (51-90 implantations/year) quintile: surgical complications [odds ratio (OR) 0.69; confidence interval (CI) 0.60-0.78], atrial lead dislocations (OR 0.69; CI 0.59-0.80), and ventricular lead dislocations (OR 0.73; CI 0.63-0.84). Hospital annual PPM volume was directly related to indication-based implantation of relatively more complex PPM and yet inversely with procedural times and rates of early surgical complications and lead dislocations. Thus, our data suggest better performance and lower

  7. Applying a low energy HPGe detector gamma ray spectrometric technique for the evaluation of Pu/Am ratio in biological samples.

    Science.gov (United States)

    Singh, I S; Mishra, Lokpati; Yadav, J R; Nadar, M Y; Rao, D D; Pradeepkumar, K S

    2015-10-01

    The estimation of Pu/(241)Am ratio in the biological samples is an important input for the assessment of internal dose received by the workers. The radiochemical separation of Pu isotopes and (241)Am in a sample followed by alpha spectrometry is a widely used technique for the determination of Pu/(241)Am ratio. However, this method is time consuming and many times quick estimation is required. In this work, Pu/(241)Am ratio in the biological sample was estimated with HPGe detector based measurements using gamma/X-rays emitted by these radionuclides. These results were compared with those obtained from alpha spectroscopy of sample after radiochemical analysis and found to be in good agreement. Copyright © 2015 Elsevier Ltd. All rights reserved.

  8. Automatic modeling using PENELOPE of two HPGe detectors used for measurement of environmental samples by γ-spectrometry from a few sets of experimental efficiencies

    Science.gov (United States)

    Guerra, J. G.; Rubiano, J. G.; Winter, G.; Guerra, A. G.; Alonso, H.; Arnedo, M. A.; Tejera, A.; Mosqueda, F.; Martel, P.; Bolivar, J. P.

    2018-02-01

    The aim of this paper is to characterize two HPGe gamma-ray detectors used in two different laboratories for environmental radioactivity measurements, so as to perform efficiency calibrations by means of Monte Carlo Simulation. To achieve such an aim, methodologies developed in previous papers have been applied, based on the automatic optimization of the model of detector, so that the differences between computational and reference FEPEs are minimized. In this work, such reference FEPEs have been obtained experimentally from several measurements of the IAEA RGU-1 reference material for specific source-detector arrangements. The models of both detectors built through these methodologies have been validated by comparing with experimental results for several reference materials and different measurement geometries, showing deviations below 10% in most cases.

  9. Use of a low-background and anti-Compton HpGe gamma-spectrometer in analyses of environmental samples

    Energy Technology Data Exchange (ETDEWEB)

    Qiong, Su; Yamin, Gao [Ministry of Public Health, Beijing, BJ (China). Lab. of Industrial Hygiene

    1989-12-01

    The results of application of a HpGe gamma-spectrometer in the analyses of enviromental samples are reported. The spectrometer has very low background and good property of Compton suppression. By comparison between the gamma-spectra with and without anti-coincidence shield for the same samples, the advantage in analysing environmental samples became apparent. In the analyses of carp samples, the ratio of specific activities of {sup 226}Ra in the flesh and bone of the carp was 1 to 35, which is basically in agreement with the ratio of the accumulation factors 1:37, as reported in the literature. Thus the spectrometer would play an important role in the research of the transfer of radionuclides of low activity in the environment. The method of gamma-ray data processing is also described.

  10. Use of a low-background and anti-Compton HpGe gamma-spectrometer in analyses of environmental samples

    International Nuclear Information System (INIS)

    Su Qiong; Gao Yamin

    1989-01-01

    The results of application of a HpGe gamma-spectrometer in the analyses of enviromental samples are reported. The spectrometer has very low background and good property of Compton suppression. By comparison between the gamma-spectra with and without anti-coincidence shield for the same samples, the advantage in analysing environmental samples became apparent. In the analyses of carp samples, the ratio of specific activities of 226 Ra in the flesh and bone of the carp was 1 to 35, which is basically in agreement with the ratio of the accumulation factors 1:37, as reported in the literature. Thus the spectrometer would play an important role in the research of the transfer of radionuclides of low activity in the environment. The method of gamma-ray data processing is also described

  11. Precision measurement of radioactivity in gamma-rays spectrometry using two HPGe detectors (BEGe-6530 and GC0818-7600SL models comparison techniques: Application to the soil measurement

    Directory of Open Access Journals (Sweden)

    Guembou Shouop Cebastien Joel

    2017-01-01

    • Proved that the activity concentration determination in gamma spectrometry depended on the energy range emitted by a radionuclide. This study showed that the standard deviation measurement was less important to the result realized with BEGe-6530 HPGe model. Our findings were demonstrated that the results of the Broad Energy Germanium detector were more reliable.

  12. Search for 2νββ excited state transitions and HPGe characterization for surface events in GERDA phase II

    Energy Technology Data Exchange (ETDEWEB)

    Lehnert, Bjoern

    2016-03-01

    The search for the neutrinoless double beta (0νββ) decay is one of the most active fields in modern particle physics. This process is not allowed within the Standard Model and its observation would imply lepton number violation and would lead to the Majorana nature of neutrinos. The experimentally observed quantity is the half-life of the decay, which can be connected to the effective Majorana neutrino mass via nuclear matrix elements. The latter can only be determined theoretically and are currently affected by large uncertainties. To reduce these uncertainties one can investigate the well established two-neutrino double beta (2νββ) decay into the ground and excited states of the daughter isotope. These similar processes are allowed within the Standard Model. In this dissertation, the search for 2νββ decays into excited states is performed in {sup 110}Pd, {sup 102}Pd and {sup 76}Ge. Three gamma spectroscopy setups at the Felsenkeller (Germany), HADES (Belgium) and LNGS (Italy) underground laboratories are used to search for the transitions in {sup 110}Pd and {sup 102}Pd. No signal is observed leading to lower half-live bounds (90% C.I.) of 2.9 . 10{sup 20} yr, 3.9 . 10{sup 20} yr and 2.9 . 10{sup 20} yr for the 0/2νββ 2{sup +}{sub 1}, 0{sup +}{sub 1} and 2{sup +}{sub 2} transitions in {sup 110}Pd and 7.9 . 10{sup 18} yr, 9.2 . 10{sup 18} yr and 1.5 . 10{sup 19} yr for the 0/2νββ 2{sup +}{sub 1}, 0{sup +}{sub 1} and 2{sup +}{sub 2} transitions in {sup 102}Pd, respectively. This is a factor of 1.3 to 3 improvement compared to previous limits. The data of Phase I (Nov 2011 - May 2013) of the 0νββ decay experiment GERDA at LNGS is used to search for excited state transitions in {sup 76}Ge. The analysis is based on coincidences between two detectors and finds no signal. Lower half-life limits (90 % C.L.) of 1.6.10{sup 23} yr, 3.7.10{sup 23} yr and 2.3.10{sup 23} yr are obtained for the 2νββ 2{sup +}{sub 1}, 0{sup +}{sub 1} and 2{sup +}{sub 2

  13. Intra-articular administration of hyaluronic acid increases the volume of the hyaline cartilage regenerated in a large osteochondral defect by implantation of a double-network gel.

    Science.gov (United States)

    Fukui, Takaaki; Kitamura, Nobuto; Kurokawa, Takayuki; Yokota, Masashi; Kondo, Eiji; Gong, Jian Ping; Yasuda, Kazunori

    2014-04-01

    Implantation of PAMPS/PDMAAm double-network (DN) gel can induce hyaline cartilage regeneration in the osteochondral defect. However, it is a problem that the volume of the regenerated cartilage tissue is gradually reduced at 12 weeks. This study investigated whether intra-articular administration of hyaluronic acid (HA) increases the volume of the cartilage regenerated with the DN gel at 12 weeks. A total of 48 rabbits were used in this study. A cylindrical osteochondral defect created in the bilateral femoral trochlea was treated with DN gel (Group DN) or left without any implantation (Group C). In both Groups, we injected 1.0 mL of HA in the left knee, and 1.0 mL of saline solution in the right knee. Quantitative histological evaluations were performed at 2, 4, and 12 weeks, and PCR analysis was performed at 2 and 4 weeks after surgery. In Group DN, the proteoglycan-rich area was significantly greater in the HA-injected knees than in the saline-injected knees at 12 weeks (P = 0.0247), and expression of type 2 collagen, aggrecan, and Sox9 mRNAs was significantly greater in the HA-injected knees than in the saline-injected knees at 2 weeks (P = 0.0475, P = 0.0257, P = 0.0222, respectively). The intra-articular administration of HA significantly enhanced these gene expression at 2 weeks and significantly increased the volume of the hyaline cartilage regenerated by implantation of a DN gel at 12 weeks. This information is important to develop an additional method to increase the volume of the hyaline cartilage tissue in a potential cartilage regeneration strategy using the DN gel.

  14. Final report on COOMET.RI(II)-S2.Cs-137 (319/RU/04): Comparison measurements of radionuclide volume sources (Cs-137)

    Energy Technology Data Exchange (ETDEWEB)

    Korostin, S. [All Russian Research Institute for Physical-Technical and Radio-Technical Measurements (VNIIFTRI), Mendeleevo (Russian Federation); Hernandez, T.; Oropesa, P. [Center of Isotopes - Radionuclide Metrology Department (CENTIS-DMR), Habana (Cuba); Arnold, D. [Physikalisch-Technische Bundesanstalt (PTB), Braunschweig (Germany); Evseev, V. [National Scientific Centre ' Institute of Metrology' (NSC IM), Kharkov (Ukraine); Ivanukovich, A.; Milevskiy, V. [Belarusian State Institute of Metrology (BelGIM), Minsk (Belarus); Svec, A. [Slovak Institute of Metrology (SMU), Bratislava (Slovakia); Lapenas, A. [Latvian National Metrology Centre Ltd, Radiation Metrology and Testing Centre (RMTC), Salaspils (Latvia); Andonova, V. [Bulgarian Institute of Metrology - National Centre of Metrology (BIM-NCM), Sofia (Bulgaria); Steiner, V. [Ministry of the Environment - Radiation and Noise Division (ISR-MoE), Jerusalem (Israel)

    2010-04-15

    Measurements of the Cs-137 specific activity in artificial volume material of water density were performed in nine laboratories with HPGe spectrometry technique. Analysis of the gamma radiation absorption in measured material and in the most important for environmental monitoring substances (food, water, biological materials, soils) confirmed the Compton scattering as the main mechanism of interaction. The list of CMCs supported by the comparison is suggested. (authors)

  15. Final report on COOMET.RI(II)-S2.Cs-137 (319/RU/04): Comparison measurements of radionuclide volume sources (Cs-137)

    International Nuclear Information System (INIS)

    Korostin, S.; Hernandez, T.; Oropesa, P.; Arnold, D.; Evseev, V.; Ivanukovich, A.; Milevskiy, V.; Svec, A.; Lapenas, A.; Andonova, V.; Steiner, V.

    2010-01-01

    Measurements of the Cs-137 specific activity in artificial volume material of water density were performed in nine laboratories with HPGe spectrometry technique. Analysis of the gamma radiation absorption in measured material and in the most important for environmental monitoring substances (food, water, biological materials, soils) confirmed the Compton scattering as the main mechanism of interaction. The list of CMCs supported by the comparison is suggested. (authors)

  16. SU-E-T-480: Radiobiological Dose Comparison of Single Fraction SRS, Multi-Fraction SRT and Multi-Stage SRS of Large Target Volumes Using the Linear-Quadratic Formula

    International Nuclear Information System (INIS)

    Ding, C; Hrycushko, B; Jiang, S; Meyer, J; Timmerman, R

    2014-01-01

    Purpose: To compare the radiobiological effect on large tumors and surrounding normal tissues from single fraction SRS, multi-fractionated SRT, and multi-staged SRS treatment. Methods: An anthropomorphic head phantom with a centrally located large volume target (18.2 cm 3 ) was scanned using a 16 slice large bore CT simulator. Scans were imported to the Multiplan treatment planning system where a total prescription dose of 20Gy was used for a single, three staged and three fractionated treatment. Cyber Knife treatment plans were inversely optimized for the target volume to achieve at least 95% coverage of the prescription dose. For the multistage plan, the target was segmented into three subtargets having similar volume and shape. Staged plans for individual subtargets were generated based on a planning technique where the beam MUs of the original plan on the total target volume are changed by weighting the MUs based on projected beam lengths within each subtarget. Dose matrices for each plan were export in DICOM format and used to calculate equivalent dose distributions in 2Gy fractions using an alpha beta ratio of 10 for the target and 3 for normal tissue. Results: Singe fraction SRS, multi-stage plan and multi-fractionated SRT plans had an average 2Gy dose equivalent to the target of 62.89Gy, 37.91Gy and 33.68Gy, respectively. The normal tissue within 12Gy physical dose region had an average 2Gy dose equivalent of 29.55Gy, 16.08Gy and 13.93Gy, respectively. Conclusion: The single fraction SRS plan had the largest predicted biological effect for the target and the surrounding normal tissue. The multi-stage treatment provided for a more potent biologically effect on target compared to the multi-fraction SRT treatments with less biological normal tissue than single-fraction SRS treatment

  17. Analysis of the forced vibration test of the Hualien large scale soil-structure interaction model using a flexible volume substructuring method

    International Nuclear Information System (INIS)

    Tang, H.T.; Nakamura, N.

    1995-01-01

    A 1/4-scale cylindrical reactor containment model was constructed in Hualien, Taiwan for foil-structure interaction (SSI) effect evaluation and SSI analysis procedure verification. Forced vibration tests were executed before backfill (FVT-1) and after backfill (FVT-2) to characterize soil-structure system characteristics under low excitations. A number of organizations participated in the pre-test blind prediction and post-test correlation analyses of the forced vibration test using various industry familiar methods. In the current study, correlation analyses were performed using a three-dimensional flexible volume substructuring method. The results are reported and soil property sensitivities are evaluated in the paper. (J.P.N.)

  18. Large deviations

    CERN Document Server

    Deuschel, Jean-Dominique; Deuschel, Jean-Dominique

    2001-01-01

    This is the second printing of the book first published in 1988. The first four chapters of the volume are based on lectures given by Stroock at MIT in 1987. They form an introduction to the basic ideas of the theory of large deviations and make a suitable package on which to base a semester-length course for advanced graduate students with a strong background in analysis and some probability theory. A large selection of exercises presents important material and many applications. The last two chapters present various non-uniform results (Chapter 5) and outline the analytic approach that allow

  19. Exploiting Growing Stock Volume Maps for Large Scale Forest Resource Assessment: Cross-Comparisons of ASAR- and PALSAR-Based GSV Estimates with Forest Inventory in Central Siberia

    Directory of Open Access Journals (Sweden)

    Christian Hüttich

    2014-07-01

    Full Text Available Growing stock volume is an important biophysical parameter describing the state and dynamics of the Boreal zone. Validation of growing stock volume (GSV maps based on satellite remote sensing is challenging due to the lack of consistent ground reference data. The monitoring and assessment of the remote Russian forest resources of Siberia can only be done by integrating remote sensing techniques and interdisciplinary collaboration. In this paper, we assess the information content of GSV estimates in Central Siberian forests obtained at 25 m from ALOS-PALSAR and 1 km from ENVISAT-ASAR backscatter data. The estimates have been cross-compared with respect to forest inventory data showing 34% relative RMSE for the ASAR-based GSV retrievals and 39.4% for the PALSAR-based estimates of GSV. Fragmentation analyses using a MODIS-based land cover dataset revealed an increase of retrieval error with increasing fragmentation of the landscape. Cross-comparisons of multiple SAR-based GSV estimates helped to detect inconsistencies in the forest inventory data and can support an update of outdated forest inventory stands.

  20. Study on the reliability of large coal-fired and nuclear power plants. Factors affecting power plant reliability. Volume I. Final report

    International Nuclear Information System (INIS)

    1975-01-01

    The study consisted of a comparative evaluation of 2 nuclear units (Indian Point 2 - Consolidated Edison of New York, Turkey Point 4 - Florida Power and Light Company) and 2 coal-fired units (Bull Run and Widows Creek Unit 8 - Tennessee Valley Authority). The purpose of the study was to identify and assess the underlying causes of unit reliability and the causes of the observed differences in reliability performance of the units. Recommended actions for improving the reliability of one of the study units was to be presented in a format useful to other utility companies for improving reliability of their generating units. The emphasis of the study was on the aspects of management, manning, operations, and maintenance which had a significant impact on unit reliability. Volume 1 includes a summary, a description of the major findings from the comparative evaluation, conclusions based on these findings, and recommendations for improving the reliability of the below average units

  1. Glass-covering of large building volumes. An interdisciplinary evaluation of a shopping centre; Oeverglasning av stora byggnadsvolymer; En tvaervetenskaplig utvaerdering av ett koepcentrum

    Energy Technology Data Exchange (ETDEWEB)

    Oeman, R. [Royal Inst. of Tech., Stockholm (Sweden). Dept. of Building Technology

    1993-11-01

    Systematized experiences of the function of large glass- covered spaces related to shopping centres, hotels, office buildings etc. are still relatively limited. With the glazed pedestrian precincts of the rebuilt Skaerholmen Centre in Stockholm as the main object of interdisciplinary studies, the aim of this thesis is to provide additional knowledge of large glass-covered spaces (atrium buildings). The studies comprises thermal comfort, temperature conditions, ventilation, energy balance, humidity - mycology, acoustics, operation - maintenance - durability and sociology. To sum up, it is clear that in the Scandinavian climate there is every likelihood of large glass-covered spaces in the public places functioning well from a technical as well as a social point of view. The energy consumption on heating the whole complex, based on theoretical calculations and measurement, is shown to have been reduced by the order of 10%. (author) figs., tabs., 101 refs

  2. Validity limits in J-resistance curve determination: A computational approach to ductile crack growth under large-scale yielding conditions. Volume 2

    International Nuclear Information System (INIS)

    Shih, C.F.; Xia, L.; Hutchinson, J.W.

    1995-02-01

    In this report, Volume 2, Mode I crack initiation and growth under plane strain conditions in tough metals are computed using an elastic/plastic continuum model which accounts for void growth and coalescence ahead of the crack tip. The material parameters include the stress-strain properties, along with the parameters characterizing the spacing and volume fraction of voids in material elements lying in the plane of the crack. For a given set of these parameters and a specific specimen, or component, subject to a specific loading, relationships among load, load-line displacement and crack advance can be computed with no restrictions on the extent of plastic deformation. Similarly, there is no limit on crack advance, except that it must take place on the symmetry plane ahead of the initial crack. Suitably defined measures of crack tip loading intensity, such as those based on the J-integral, can also be computed, thereby directly generating crack growth resistance curves. In this report, the model is applied to five specimen geometries which are known to give rise to significantly different crack tip constraints and crack growth resistance behaviors. Computed results are compared with sets of experimental data for two tough steels for four of the specimen types. Details of the load, displacement and crack growth histories are accurately reproduced, even when extensive crack growth takes place under conditions of fully plastic yielding. A description of material resistance to crack initiation and subsequent growth is essential for assessing structural integrity such as nuclear pressure vessels and piping

  3. Under conditions of large geometric miss, tumor control probability can be higher for static gantry intensity-modulated radiation therapy compared to volume-modulated arc therapy for prostate cancer

    International Nuclear Information System (INIS)

    Balderson, Michael; Brown, Derek; Johnson, Patricia; Kirkby, Charles

    2016-01-01

    The purpose of this work was to compare static gantry intensity-modulated radiation therapy (IMRT) with volume-modulated arc therapy (VMAT) in terms of tumor control probability (TCP) under scenarios involving large geometric misses, i.e., those beyond what are accounted for when margin expansion is determined. Using a planning approach typical for these treatments, a linear-quadratic–based model for TCP was used to compare mean TCP values for a population of patients who experiences a geometric miss (i.e., systematic and random shifts of the clinical target volume within the planning target dose distribution). A Monte Carlo approach was used to account for the different biological sensitivities of a population of patients. Interestingly, for errors consisting of coplanar systematic target volume offsets and three-dimensional random offsets, static gantry IMRT appears to offer an advantage over VMAT in that larger shift errors are tolerated for the same mean TCP. For example, under the conditions simulated, erroneous systematic shifts of 15 mm directly between or directly into static gantry IMRT fields result in mean TCP values between 96% and 98%, whereas the same errors on VMAT plans result in mean TCP values between 45% and 74%. Random geometric shifts of the target volume were characterized using normal distributions in each Cartesian dimension. When the standard deviations were doubled from those values assumed in the derivation of the treatment margins, our model showed a 7% drop in mean TCP for the static gantry IMRT plans but a 20% drop in TCP for the VMAT plans. Although adding a margin for error to a clinical target volume is perhaps the best approach to account for expected geometric misses, this work suggests that static gantry IMRT may offer a t