WorldWideScience

Sample records for large size containers

  1. Comparative analysis of non-destructive methods to control fissile materials in large-size containers

    Directory of Open Access Journals (Sweden)

    Batyaev V.F.

    2017-01-01

    Full Text Available The analysis of various non-destructive methods to control fissile materials (FM in large-size containers filled with radioactive waste (RAW has been carried out. The difficulty of applying passive gamma-neutron monitoring FM in large containers filled with concreted RAW is shown. Selection of an active non-destructive assay technique depends on the container contents; and in case of a concrete or iron matrix with very low activity and low activity RAW the neutron radiation method appears to be more preferable as compared with the photonuclear one.

  2. Measurement of fissile mass in large-size containers with a transportable linear accelerator

    Science.gov (United States)

    Romeyer Dherbey, Jacques; Lyoussi, A.; Buisson, A.

    1997-02-01

    The quantification of transuranic material (TRU) in waste packages is a common problem of countries working in the field of nuclear nondestructive inspection. The direct measurement of TRU mass inside large size closed containers is difficult due to several effects, mainly the matrix attenuation and uncertainty on the localization of the radioactive mass. The present document describes the method being developed to assay conditioned waste packages using a transportable linear accelerator which is called Mini- Linatron. The system uses a pulsed electron beam from the Mini-Linatron to produce high energy bremsstrahlung photon bursts from thin metallic converter. The transportable linear accelerator operates at 6, 9 and 11 MeV with a repetition rate between 10 to 300 Hz and a 4.5 microsecond(s) pulse duration. The maximum gamma dose rate is about 23 Gy/mn at 1 m. The photons induce fission in fissile and fertile nuclei. We counted delayed neutrons emitted after each pulse by using Sequential Photon Interrogation and Neutron Counting Signatures technique which has ben developed in this framework. Results of measurements on an experimental active gamma interrogation facility for embedded intermediate and low level wastes are presented. Finally, the advantages and performances of the photofission interrogation technique, the use of a transportable electron linear accelerator as a particle source, and the experimental and electronic details will be discussed.

  3. Large litter sizes

    DEFF Research Database (Denmark)

    Sandøe, Peter; Rutherford, K.M.D.; Berg, Peer

    2012-01-01

    This paper presents some key results and conclusions from a review (Rutherford et al. 2011) undertaken regarding the ethical and welfare implications of breeding for large litter size in the domestic pig and about different ways of dealing with these implications. Focus is primarily on the direct...... adverse consequences for animal welfare of Danish breeding for large litter sizes due to increased piglet mortality and the subsequent attempts to reverse these consequences by breeding for number of live piglets at day five rather than number of piglets born. By this change of breeding goal it seems...

  4. Large litter sizes

    DEFF Research Database (Denmark)

    Sandøe, Peter; Rutherford, K.M.D.; Berg, Peer

    2012-01-01

    This paper presents some key results and conclusions from a review (Rutherford et al. 2011) undertaken regarding the ethical and welfare implications of breeding for large litter size in the domestic pig and about different ways of dealing with these implications. Focus is primarily on the direct...

  5. Container size influences snack food intake independently of portion size.

    Science.gov (United States)

    Marchiori, David; Corneille, Olivier; Klein, Olivier

    2012-06-01

    While larger containers have been found to increase food intake, it is unclear whether this effect is driven by container size, portion size, or their combination, as these variables are usually confounded. The study was advertised as examining the effects of snack food consumption on information processing and participants were served M&M's for free consumption in individual cubicles while watching a TV show. Participants were served (1) a medium portion of M&M's in a small (n=30) or (2) in a large container (n=29), or (3) a large portion in a large container (n=29). The larger container increased intake by 129% (199 kcal) despite holding portion size constant, while controlling for different confounding variables. This research suggests that larger containers stimulate food intake over and above their impact on portion size.

  6. Large Size Telescope Report

    CERN Document Server

    Mazin, D; Teshima, M

    2016-01-01

    The Cherenkov Telescope Array (CTA) observatory will be deployed over two sites in the two hemispheres. Both sites will be equipped with four Large Size Telescopes (LSTs), which are crucial to achieve the science goals of CTA in the 20-200 GeV energy range. Each LST is equipped with a primary tessellated mirror dish of 23 m diameter, supported by a structure made mainly of carbon fibre reinforced plastic tubes and aluminum joints. This solution guarantees light weight (around 100 tons), essential for fast repositioning to any position in the sky in <20 seconds. The camera is composed of 1855 photomultiplier tubes and embeds the control, readout and trigger electronics. The detailed design is now complete and production of the first LST, which will serve as a prototype for the remaining seven, is ongoing. The installation of the first LST at the Roque de los Muchachos Observatory on the Canary island of La Palma (Spain) started in July 2016. In this paper we will outline the technical solutions adopted to f...

  7. Large size telescope report

    Science.gov (United States)

    Mazin, D.; Cortina, J.; Teshima, M.

    2017-01-01

    The Cherenkov Telescope Array (CTA) observatory will be deployed over two sites in the two hemispheres. Both sites will be equipped with four Large Size Telescopes (LSTs), which are crucial to achieve the science goals of CTA in the 20-200 GeV energy range. Each LST is equipped with a primary tessellated mirror dish of 23 m diameter, supported by a structure made mainly of carbon fibre reinforced plastic tubes and aluminum joints. This solution guarantees light weight (around 100 tons), essential for fast repositioning to any position in the sky in <20 seconds. The camera is composed of 1855 photomultiplier tubes and embeds the control, readout and trigger electronics. The detailed design is now complete and production of the first LST, which will serve as a prototype for the remaining seven, is ongoing. The installation of the first LST at the Roque de los Muchachos Observatory on the Canary island of La Palma (Spain) started in July 2016. In this paper we will outline the technical solutions adopted to fulfill the design requirements, present results of element prototyping and describe the installation and operation plans.

  8. Development and Testing of Techniques for In-Ground Stabilization, Size Reduction and Safe Removal of Radioactive Wastes Stored in Large Containments in Burial Grounds - 13591

    Energy Technology Data Exchange (ETDEWEB)

    Halliwell, Stephen [VJ Technologies Inc, 89 Carlough Road, Bohemia, NY (United States)

    2013-07-01

    Radioactive waste materials, including Transuranic (TRU) wastes from laboratories have been stored below ground in large containments at a number of sites in the US DOE Complex, and at nuclear sites in Europe. These containments are generally referred to as caissons or shafts. The containments are in a range of sizes and depths below grade. The caissons at the DOE's Hanford site are cylindrical, of the order of 2,500 mm in diameter, 3,050 mm in height and are buried about 6,000 mm below grade. One type of caisson is made out of corrugated pipe, whereas others are made of concrete with standard re-bar. However, the larger shafts in the UK are of the order of 4,600 mm in diameter, 53,500 mm deep, and 12,000 below grade. This paper describes the R and D work and testing activities performed to date to evaluate the concept of in-ground size reduction and stabilization of the contents of large containments similar to those at Hanford. In practice, the height of the Test Facility provided for a test cell that was approximately 22' deep. That prevented a 'full scale mockup' test in the sense that the Hanford Caisson configuration would be an identical replication. Therefore, the project was conducted in two phases. The first phase tested a simulated Caisson with surrogate contents, and part of a Chute section, and the second phase tested a full chute section. These tests were performed at VJ Technologies Test Facility located in East Haven, CT, as part of the Proof of Design Concept program for studying the feasibility of an in-situ grout/grind/mix/stabilize technology for the remediation of four caissons at the 618-11 Burial Ground at US Department of Energy Hanford Site. The test site was constructed such that multiple testing areas were provided for the evaluation of various tools, equipment and procedures under conditions that simulated the Hanford site, with representative soils and layout dimensions. (authors)

  9. The mosquito Aedes aegypti has a large genome size and high transposable element load but contains a low proportion of transposon-specific piRNAs

    Science.gov (United States)

    2011-01-01

    Background The piRNA pathway has been shown in model organisms to be involved in silencing of transposons thereby providing genome stability. In D. melanogaster the majority of piRNAs map to these sequences. The medically important mosquito species Aedes aegypti has a large genome size, a high transposon load which includes Miniature Inverted repeat Transposable Elements (MITES) and an expansion of the piRNA biogenesis genes. Studies of transgenic lines of Ae. aegypti have indicated that introduced transposons are poorly remobilized and we sought to explore the basis of this. We wished to analyze the piRNA profile of Ae. aegypti and thereby determine if it is responsible for transposon silencing in this mosquito. Results Estimated piRNA sequence diversity was comparable between Ae. aegypti and D. melanogaster, but surprisingly only 19% of mosquito piRNAs mapped to transposons compared to 51% for D. melanogaster. Ae. aegypti piRNA clusters made up a larger percentage of the total genome than those of D. melanogaster but did not contain significantly higher percentages of transposon derived sequences than other regions of the genome. Ae. aegypti contains a number of protein coding genes that may be sources of piRNA biogenesis with two, traffic jam and maelstrom, implicated in this process in model organisms. Several genes of viral origin were also targeted by piRNAs. Examination of six mosquito libraries that had previously been transformed with transposon derived sequence revealed that new piRNA sequences had been generated to the transformed sequences, suggesting that they may have stimulated a transposon inactivation mechanism. Conclusions Ae. aegypti has a large piRNA complement that maps to transposons but primarily gene sequences, including many viral-derived sequences. This, together the more uniform distribution of piRNA clusters throughout its genome, suggest that some aspects of the piRNA system differ between Ae. aegypti and D. melanogaster. PMID:22171608

  10. The mosquito Aedes aegypti has a large genome size and high transposable element load but contains a low proportion of transposon-specific piRNAs

    Directory of Open Access Journals (Sweden)

    Arensburger Peter

    2011-12-01

    Full Text Available Abstract Background The piRNA pathway has been shown in model organisms to be involved in silencing of transposons thereby providing genome stability. In D. melanogaster the majority of piRNAs map to these sequences. The medically important mosquito species Aedes aegypti has a large genome size, a high transposon load which includes Miniature Inverted repeat Transposable Elements (MITES and an expansion of the piRNA biogenesis genes. Studies of transgenic lines of Ae. aegypti have indicated that introduced transposons are poorly remobilized and we sought to explore the basis of this. We wished to analyze the piRNA profile of Ae. aegypti and thereby determine if it is responsible for transposon silencing in this mosquito. Results Estimated piRNA sequence diversity was comparable between Ae. aegypti and D. melanogaster, but surprisingly only 19% of mosquito piRNAs mapped to transposons compared to 51% for D. melanogaster. Ae. aegypti piRNA clusters made up a larger percentage of the total genome than those of D. melanogaster but did not contain significantly higher percentages of transposon derived sequences than other regions of the genome. Ae. aegypti contains a number of protein coding genes that may be sources of piRNA biogenesis with two, traffic jam and maelstrom, implicated in this process in model organisms. Several genes of viral origin were also targeted by piRNAs. Examination of six mosquito libraries that had previously been transformed with transposon derived sequence revealed that new piRNA sequences had been generated to the transformed sequences, suggesting that they may have stimulated a transposon inactivation mechanism. Conclusions Ae. aegypti has a large piRNA complement that maps to transposons but primarily gene sequences, including many viral-derived sequences. This, together the more uniform distribution of piRNA clusters throughout its genome, suggest that some aspects of the piRNA system differ between Ae. aegypti and D

  11. Large size space construction for space exploitation

    Science.gov (United States)

    Kondyurin, Alexey

    2016-07-01

    Space exploitation is impossible without large space structures. We need to make sufficient large volume of pressurized protecting frames for crew, passengers, space processing equipment, & etc. We have to be unlimited in space. Now the size and mass of space constructions are limited by possibility of a launch vehicle. It limits our future in exploitation of space by humans and in development of space industry. Large-size space construction can be made with using of the curing technology of the fibers-filled composites and a reactionable matrix applied directly in free space. For curing the fabric impregnated with a liquid matrix (prepreg) is prepared in terrestrial conditions and shipped in a container to orbit. In due time the prepreg is unfolded by inflating. After polymerization reaction, the durable construction can be fitted out with air, apparatus and life support systems. Our experimental studies of the curing processes in the simulated free space environment showed that the curing of composite in free space is possible. The large-size space construction can be developed. A project of space station, Moon base, Mars base, mining station, interplanet space ship, telecommunication station, space observatory, space factory, antenna dish, radiation shield, solar sail is proposed and overviewed. The study was supported by Humboldt Foundation, ESA (contract 17083/03/NL/SFe), NASA program of the stratospheric balloons and RFBR grants (05-08-18277, 12-08-00970 and 14-08-96011).

  12. Optical encryption for large-sized images

    Science.gov (United States)

    Sanpei, Takuho; Shimobaba, Tomoyoshi; Kakue, Takashi; Endo, Yutaka; Hirayama, Ryuji; Hiyama, Daisuke; Hasegawa, Satoki; Nagahama, Yuki; Sano, Marie; Oikawa, Minoru; Sugie, Takashige; Ito, Tomoyoshi

    2016-02-01

    We propose an optical encryption framework that can encrypt and decrypt large-sized images beyond the size of the encrypted image using our two methods: random phase-free method and scaled diffraction. In order to record the entire image information on the encrypted image, the large-sized images require the random phase to widely diffuse the object light over the encrypted image; however, the random phase gives rise to the speckle noise on the decrypted images, and it may be difficult to recognize the decrypted images. In order to reduce the speckle noise, we apply our random phase-free method to the framework. In addition, we employ scaled diffraction that calculates light propagation between planes with different sizes by changing the sampling rates.

  13. HYDRODYNAMIC CHARACTERISTICS OF FLUIDIZED BEDS CONTAINING LARGE POLYDISPERSED PARTICLES

    Directory of Open Access Journals (Sweden)

    K. TANNOUS

    1998-03-01

    Full Text Available This paper presents a hydrodynamic study of fluidized beds containing large polydispersed particles (B and D categories of Geldart’s classification. The experiments have been carried out with particle samples characterized by the Rosin-Rammler-Sperling (RRS size distribution. The parameters analyzed in this study are the dispersion index and the average particle diameter obtained from the RRS size distribution model. Correlations to estimate the initial and complete fluidization velocities and the segregation velocity as a function of these two size distribution parameters have been established.

  14. Large size metallic glass gratings by embossing

    Science.gov (United States)

    Ma, J.; Yi, J.; Zhao, D. Q.; Pan, M. X.; Wang, W. H.

    2012-09-01

    Bulk metallic glasses have excellent thermoforming ability in their wide supercooled liquid region. We show that large-size metallic glass grating (˜8 × 8 mm2) with fine periodicity and ultra smooth surface feature can be readily fabricated by hot embossing. The method for fabrication of gratings is proved to be much cheaper, and requires low pressure and short time (less than 30 s). The metallic glass gratings exhibit comparable optical properties such as rainbow-like spectrum when shone by fluorescent lamp light.

  15. The Cherenkov Telescope Array Large Size Telescope

    CERN Document Server

    Ambrosi, G; Baba, H; Bamba, A; Barceló, M; de Almeida, U Barres; Barrio, J A; Bigas, O Blanch; Boix, J; Brunetti, L; Carmona, E; Chabanne, E; Chikawa, M; Colin, P; Conteras, J L; Cortina, J; Dazzi, F; Deangelis, A; Deleglise, G; Delgado, C; Díaz, C; Dubois, F; Fiasson, A; Fink, D; Fouque, N; Freixas, L; Fruck, C; Gadola, A; García, R; Gascon, D; Geffroy, N; Giglietto, N; Giordano, F; Grañena, F; Gunji, S; Hagiwara, R; Hamer, N; Hanabata, Y; Hassan, T; Hatanaka, K; Haubold, T; Hayashida, M; Hermel, R; Herranz, D; Hirotani, K; Inoue, S; Inoue, Y; Ioka, K; Jablonski, C; Kagaya, M; Katagiri, H; Kishimoto, T; Kodani, K; Kohri, K; Konno, Y; Koyama, S; Kubo, H; Kushida, J; Lamanna, G; Flour, T Le; López-Moya, M; López, R; Lorenz, E; Majumdar, P; Manalaysay, A; Mariotti, M; Martínez, G; Martínez, M; Mazin, D; Miranda, J M; Mirzoyan, R; Monteiro, I; Moralejo, A; Murase, K; Nagataki, S; Nakajima, D; Nakamori, T; Nishijima, K; Noda, K; Nozato, A; Ohira, Y; Ohishi, M; Ohoka, H; Okumura, A; Orito, R; Panazol, J L; Paneque, D; Paoletti, R; Paredes, J M; Pauletta, G; Podkladkin, S; Prast, J; Rando, R; Reimann, O; Ribó, M; Rosier-Lees, S; Saito, K; Saito, T; Saito, Y; Sakaki, N; Sakonaka, R; Sanuy, A; Sasaki, H; Sawada, M; Scalzotto, V; Schultz, S; Schweizer, T; Shibata, T; Shu, S; Sieiro, J; Stamatescu, V; Steiner, S; Straumann, U; Sugawara, R; Tajima, H; Takami, H; Tanaka, S; Tanaka, M; Tejedor, L A; Terada, Y; Teshima, M; Totani, T; Ueno, H; Umehara, K; Vollhardt, A; Wagner, R; Wetteskind, H; Yamamoto, T; Yamazaki, R; Yoshida, A; Yoshida, T; Yoshikoshi, T

    2013-01-01

    The two arrays of the Very High Energy gamma-ray observatory Cherenkov Telescope Array (CTA) will include four Large Size Telescopes (LSTs) each with a 23 m diameter dish and 28 m focal distance. These telescopes will enable CTA to achieve a low-energy threshold of 20 GeV, which is critical for important studies in astrophysics, astroparticle physics and cosmology. This work presents the key specifications and performance of the current LST design in the light of the CTA scientific objectives.

  16. Optimized production and concentration of lentiviral vectors containing large inserts.

    Science.gov (United States)

    al Yacoub, Nadya; Romanowska, Malgorzata; Haritonova, Natalie; Foerster, John

    2007-07-01

    Generation of high titer lentiviral stocks and efficient virus concentration are central to maximize the utility of lentiviral technology. Here we evaluate published protocols for lentivirus production on a range of transfer vectors differing in size (7.5-13.2 kb). We present a modified virus production protocol robustly yielding useful titers (up to 10(7)/ml) for a range of different transfer vectors containing packaging inserts up to 7.5 kb. Moreover, we find that virus recovery after concentration by ultracentrifugation depends on the size of the packaged inserts, heavily decreasing for large packaged inserts. We describe a fast (4 h) centrifugation protocol at reduced speed allowing high virus recovery even for large and fragile lentivirus vectors. The protocols outlined in the current report should be useful for many labs interested in producing and concentrating high titer lentiviral stocks.

  17. Texture development during recrystallization of aluminium containing large particles

    DEFF Research Database (Denmark)

    Juul Jensen, Dorte; Hansen, Niels; Humphreys, F. J.

    1985-01-01

    The recrystallization process in heavily deformed commercially pure aluminium containing large intermetallic particles was studied by in situ neutron diffraction texture measurements and various microscopical techniques including texture measurements in local areas and simultaneous determination...... of size and orientation of individual grains. The formation and growth of recrystallization nuclei at the particles and in the matrix were examined by correlating the measured change in texture to the observed change in microstructure. It was found that prolific nucleation of grains having a wide spread...... of orientations takes place close to larger particles or clusters of particles early in the recrystallization process. The texture of fully recrystallized material, however, contains only a relatively weak random component showing that the randomisation effect of the particles was limited. This was ascribed...

  18. Novel Metal Gallophosphates Containing Nano-Sized Channels

    Institute of Scientific and Technical Information of China (English)

    WANG; SueLein

    2001-01-01

    Substitution of the first-raw transition netal (TM) ions for Al34 in the frameworks of aluminum phosphates is of particular interest for the enhancement of catalytic activity and the design of novel catalysts. The location and environment of the TM ion site is of considerable importance for understanding the catalytic and adsorptive properties of molecular sieves. As only few single-crystal data available for most of the MAlPO-n samples, actual incorporation of TM ions into the tetrahedral frameworks is difficult to prove.1 Owing to the similarity in the framework topology, the search for gallium phosphates adopting microporous structures has attracted much attention.2,3 One of the main goals of this research is to synthesize zeolite-like materials in the Ga/P/O system with large ring sizes so that one can perform shape-selective catalysis on reactants too large to enter the pores of currently employed industrial catalysts. In 1988, Davis et al. reported a material called VPI-5 that contained an 18-membered ring. It was not until 1991 that a gallophosphate with gigantic pores of20-ring was prepared, namely, cloverite. Recently, the pore size has been extended to 24-membered ring in the transition metal phosphates, i.e. ND-l, and VSB-1. These materials have set the stage for the development of other extra-large pore, crystalline molecular sieves. In contrast, the largest pore ever discovered among the phosphates of Group 13 elements has only 20-membered rings and exists in three materials: cloverite, JDF-20, and [NH3(CH2)4NH3]2[Ga4(OH)3(PO4)3(HPO4)2]·xH2O. Attempts to prepare materials with even wider pores have produced a novel gallophosphate, [Ga2(DETA)(PO4)2]·2H2O (DETA = diethylenetriamine) (referred to as NTHU-1). The incorporation of divalent heteroatoms into the framework of NTHU-1 has been exceptionally successful. In this presentation, the hydrothermal syntheses, crystal structures, thermal behavior, and magnetic properties of a series of transition

  19. Novel Metal Gallophosphates Containing Nano-Sized Channels

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    @@ Substitution of the first-raw transition netal (TM) ions for Al34 in the frameworks of aluminum phosphates is of particular interest for the enhancement of catalytic activity and the design of novel catalysts. The location and environment of the TM ion site is of considerable importance for understanding the catalytic and adsorptive properties of molecular sieves. As only few single-crystal data available for most of the MAlPO-n samples, actual incorporation of TM ions into the tetrahedral frameworks is difficult to prove.1 Owing to the similarity in the framework topology, the search for gallium phosphates adopting microporous structures has attracted much attention.2,3 One of the main goals of this research is to synthesize zeolite-like materials in the Ga/P/O system with large ring sizes so that one can perform shape-selective catalysis on reactants too large to enter the pores of currently employed industrial catalysts. In 1988, Davis et al. reported a material called VPI-5 that contained an 18-membered ring. It was not until 1991 that a gallophosphate with gigantic pores of20-ring was prepared, namely, cloverite. Recently, the pore size has been extended to 24-membered ring in the transition metal phosphates, i.e. ND-l, and VSB-1. These materials have set the stage for the development of other extra-large pore, crystalline molecular sieves. In contrast, the largest pore ever discovered among the phosphates of Group 13 elements has only 20-membered rings and exists in three materials: cloverite, JDF-20, and [NH3(CH2)4NH3]2[Ga4(OH)3(PO4)3(HPO4)2]@xH2O. Attempts to prepare materials with even wider pores have produced a novel gallophosphate, [Ga2(DETA)(PO4)2]@2H2O (DETA = diethylenetriamine) (referred to as NTHU-1). The incorporation of divalent heteroatoms into the framework of NTHU-1 has been exceptionally successful. In this presentation, the hydrothermal syntheses, crystal structures, thermal behavior, and magnetic properties of a series of transition

  20. Cluster dynamics largely shapes protoplanetary disc sizes

    CERN Document Server

    Vincke, Kirsten

    2016-01-01

    It is still on open question to what degree the cluster environment influences the sizes of protoplanetary discs surrounding young stars. Particularly so for the short-lived clusters typical for the solar neighbourhood in which the stellar density and therefore the influence of the cluster environment changes considerably over the first 10 Myr. In previous studies often the effect of the gas on the cluster dynamics has been neglected, this is remedied here. Using the code NBody6++ we study the stellar dynamics in different developmental phases - embedded, expulsion, expansion - including the gas and quantify the effect of fly-bys on the disc size. We concentrate on massive clusters ($M_{\\text{cl}} \\geq 10^3 - 6 \\cdot 10^4 M_{\\text{Sun}}$), which are representative for clusters like the Orion Nebula Cluster (ONC) or NGC 6611. We find that not only the stellar density but also the duration of the embedded phase matters. The densest clusters react fastest to the gas expulsion and drop quickly in density, here 98...

  1. Large volume production of large size GaAs substrates and epitaxial wafers for microwave devices

    OpenAIRE

    Otoki, Y.; Kamogawa, H.; Ohnishi, M.; Inada, T.; Kashiwa, M.; Sakaguchi, H.

    1999-01-01

    Recent mass production techniques for LEC substrates and MOVPE wafers for microwave devices are described. Huge GaAs semi-insulating ingots (150mm diam., 310mm long) was obtained by Multi-hot-zone very large size pullar. Three step boule annealing and fully-automated process enabled mass production of the large size substrates. Epitaxiial wafers with abrupt hetero interface, excellent uniformity and reproducibility are producing largely by face down horizontal flow type MOVPE system, which ca...

  2. Resolution of the direct containment heating issue for all Westinghouse plants with large dry containments or subatmospheric containments

    Energy Technology Data Exchange (ETDEWEB)

    Pilch, M.M.; Allen, M.D.; Klamerus, E.W. [Sandia National Labs., Albuquerque, NM (United States)

    1996-03-01

    This report uses the methodology and scenarios described in NUREG/CR-6075 and NUREG/CR-6075, Supplement 1, to address the direct containment heating (DCH) issue for all Westinghouse plants with large dry or subatmospheric containments. DCH is considered resolved if the conditional containment failure probability (CCFP) is less than 0.1. The methodology calls for an initial screening phase in which the CCFP for each plant is calculated based on loads versus strength evaluations using plant-specific information. The DCH issue is considered resolved for a plant if the CCFP calculated in the screening phase is less than 0.01. This value is more stringent than the overall success criterion of 0.1. The CCFPs for all of the Westinghouse plants with dry containments were less than 0.01 in the screening phase calculations, and thus, the DCH issue is resolved for these plants based on containment loads alone. No additional analyses are required.

  3. Spray deposition for making large size billet with swing atomizer

    Institute of Scientific and Technical Information of China (English)

    LI Jian-ping; LIU Tao; TANG Qing-yun; HAN Lei; ZHONG Jue

    2008-01-01

    The movement mode of the atomizer is a very important parameter during spray deposition process, which has direct influence on the size and surface texture of the billets. To resolve the problem of manufacturing large size billets, a method of spray deposition by the atomizer with off-center swing was put forward. The atomizer was driven by the alternating current servomotor to swing within 7° at varying speed. The influence of the atomizer parameters, such as translation of the atomizer, swing angle of the atomizer, substrate falling speed and spraying pressure, on the spray deposition was studied. The optimized parameters of the spray deposition process were obtained. The results show that the large size billets with uniform surface quality can be made through adjusting swing frequency and angle of the atomizer, offset distance of the atomizer and inclined angle of the substrate; the valid spray area will decrease and the dimension of top surface will reduce when pressure is less than 0.4 MPa within certain spray distance; meantime, the moving time and cooling time of the droplets are extended, which will lead to loose structure and bad densification. When the pressure, the swing angle and the eccentric offset of the atomization equal 0.5MPa, 7° and 60mm,respectively, large size billets with fine texture and diameter of 500mm can be produced.

  4. Multispectral Acquisition of Large-Sized Pictorial Surfaces

    Directory of Open Access Journals (Sweden)

    Paviotti Anna

    2009-01-01

    Full Text Available Multispectral acquisition of artworks has recently received considerable attention in the image processing community. Quite understandably, so far this attention has mainly focused on paintings, given their predominant role in museum collections. It is worth pointing out that the instrumentation and procedures used for acquiring regular paintings are not suited for the multispectral acquisition of large-sized painted surfaces such as frescoed halls and great paintings. Given the relevance of such artifacts, and their widespread presence in churches or historical buildings due to their social function, the problem of finding suitable techniques for their acquisition is certainly worth addressing. This paper focuses on multispectral acquisition of large-sized pictorial surfaces, systematically addressing the practical issues related to the acquisition equipment and procedure. Given the crucial role played by the illumination in this application, special attention is given to this issue. The proposed approach is supported by experimental results.

  5. Accuracy of the photogrametric measuring system for large size elements

    Directory of Open Access Journals (Sweden)

    M. Grzelka

    2011-04-01

    Full Text Available The aim of this paper is to present methods of estimating and guidelines for verifying the accuracy of optical photogrammetric measuringsystems, using for measurement of large size elements. Measuring systems applied to measure workpieces of a large size which oftenreach more than 10000mm require use of appropriate standards. Those standards provided by the manufacturer of photogrammetricsystems are certified and are inspected annually. To make sure that these systems work properly there was developed a special standardVDI / VDE 2634, "Optical 3D measuring systems. Imaging systems with point - by - point probing. " According to recommendationsdescribed in this standard research on accuracy of photogrametric measuring system was conducted using K class gauge blocks dedicatedto calibrate and test accuracy of classic CMMs. The paper presents results of research of estimation the actual error of indication for sizemeasurement MPEE for photogrammetric coordinate measuring system TRITOP.

  6. Containment of Solid Wastes in some Large Scandinavian Cities

    DEFF Research Database (Denmark)

    Du-Thinh, Kien

    1998-01-01

    Two kinds of containment of solid wastes - one in the vicinity of Copenhagen, the capital of Denmark, another on the outskirts of Gothenburg, the second largest city of sweden - are reviewed in this article. They represent two different approaches to waste management. Special attention is given...... to the geological-geotechnical characteristics of the subsoil of the waste sites which determine to a large extent the risks of infiltration and transport of leachates. The role of the barrier, its design and construction or the consequences arising from the lack of abarrier are dealt with herein. The monitoring...

  7. Biological Conservation of Giant Limpets: The Implications of Large Size.

    Science.gov (United States)

    Espinosa, F; Rivera-Ingraham, G A

    Patellogastropods, also known as true limpets, are distributed throughout the world and constitute key species in coastal ecosystems. Some limpet species achieve remarkable sizes, which in the most extreme cases can surpass 35cm in shell length. In this review, we focus on giant limpets, which are defined as those with a maximum shell size surpassing 10cm. According to the scientific literature, there are a total of 14 species across five genera that reach these larger sizes. Four of these species are threatened or in danger of extinction. Inhabiting the intertidal zones, limpets are frequently affected by anthropogenic impacts, namely collection by humans, pollution and habitat fragmentation. In the case of larger species, their conspicuous size has made them especially prone to human collection since prehistoric times. Size is not phylogeny-dependent among giant limpets, but is instead related to behavioural traits instead. Larger-sized species tend to be nonmigratory and territorial compared to those that are smaller. Collection by humans has been cited as the main cause behind the decline and/or extinction of giant limpet populations. Their conspicuously large size makes them the preferred target of human collection. Because they are protandric species, selectively eliminating larger specimens of a given population seriously compromises their viability and has led to local extinction events in some cases. Additionally, sustained collection over time may lead to microevolutionary responses that result in genetic changes. The growing presence of artificial structures in coastal ecosystems may cause population fragmentation and isolation, limiting the genetic flow and dispersion capacity of many limpet species. However, when they are necessitated, artificial structures could be managed to establish marine artificial microreserves and contribute to the conservation of giant limpet species that naturally settle on them. © 2017 Elsevier Ltd. All rights reserved.

  8. Technological Aspects of Creating Large-size Optical Telescopes

    Directory of Open Access Journals (Sweden)

    V. V. Sychev

    2015-01-01

    Full Text Available A concept of the telescope creation, first of all, depends both on a choice of the optical scheme to form optical radiation and images with minimum losses of energy and information and on a choice of design to meet requirements for strength, stiffness, and stabilization characteristics in real telescope operation conditions. Thus, the concept of creating large-size telescopes, certainly, involves the use of adaptive optics methods and means.The level of technological capabilities to realize scientific and engineering ideas define a successful development of large-size optical telescopes in many respects. All developers pursue the same aim that is to raise an amount of information by increasing a main mirror diameter of the telescope.The article analyses the adaptive telescope designs developed in our country. Using a domestic ACT-25 telescope as an example, it considers creation of large-size optical telescopes in terms of technological aspects. It also describes the telescope creation concept features, which allow reaching marginally possible characteristics to ensure maximum amount of information.The article compares a wide range of large-size telescopes projects. It shows that a domestic project to create the adaptive ACT-25 super-telescope surpasses its foreign counterparts, and there is no sense to implement Euro50 (50m and OWL (100m projects.The considered material gives clear understanding on a role of technological aspects in development of such complicated optic-electronic complexes as a large-size optical telescope. The technological criteria of an assessment offered in the article, namely specific informational content of the telescope, its specific mass, and specific cost allow us to reveal weaknesses in the project development and define a reserve regarding further improvement of the telescope.The analysis of results and their judgment have shown that improvement of optical largesize telescopes in terms of their maximum

  9. Nuclear states with anomalously large radius (size isomers)

    Energy Technology Data Exchange (ETDEWEB)

    Ogloblin, A. A.; Demyanova, A. S., E-mail: a.s.demyanova@bk.ru; Danilov, A. N. [National Research Center Kurchatov Institute (Russian Federation); Belyaeva, T. L. [Ciudad Universitaria, Universidad Nacional Autónoma de Meéxico (Mexico); Goncharov, S. A. [Moscow State University, Faculty of Physics (Russian Federation); Trzaska, W. [University of Jyvaäskylaä (Finland)

    2016-07-15

    Methods of determination of the nuclear excited state radii are discussed together with the recently obtained data on the states of some light nuclei having abnormally large radii (size isomers). It is shown that such states include excited neutron-halo states in {sup 9}Be, {sup 11}Be, and {sup 13}C and some alpha-cluster states in {sup 12}C, {sup 11}B, and {sup 13}C. Among the latter ones, there is the well-known Hoyle state in {sup 12}C—the structure of this state exhibit rudimentary features of alpha-particle states.

  10. Assessment of whipping and springing on a large container vessel

    Directory of Open Access Journals (Sweden)

    Barhoumi Mondher

    2014-06-01

    Full Text Available Wave induced vibrations increase the fatigue and extreme loading, but this is normally neglected in design. The industry view on this is changing. Wave induced vibrations are often divided into springing and whipping, and their relative contribution to fatigue and extreme loading varies depending on ship design. When it comes to displacement vessels, the contribution from whipping on fatigue and extreme loading is particularly high for certain container vessels. A large modern design container vessel with high bow flare angle and high service speed has been considered. The container vessel was equipped with a hull monitoring system from a recognized supplier of HMON systems. The vessel has been operating between Asia and Europe for a few years and valuable data has been collected. Also model tests have been carried out of this vessel to investigate fatigue and extreme loading, but model tests are often limited to head seas. For the full scale measurements, the correlation between stress data and wind data has been investigated. The wave and vibration damage are shown versus heading and Beaufort strength to indicate general trends. The wind data has also been compared to North Atlantic design environment. Even though it has been shown that the encountered wind data has been much less severe than in North Atlantic, the extreme loading defined by IACS URS11 is significantly exceeded when whipping is included. If whipping may contribute to collapse, then proper seamanship may be useful in order to limit the extreme loading. The vibration damage is also observed to be high from head to beam seas, and even present in stern seas, but fatigue damage in general is low on this East Asia to Europe trade.

  11. Vertebral Adaptations to Large Body Size in Theropod Dinosaurs

    Science.gov (United States)

    Wilson, John P.; Woodruff, D. Cary; Gardner, Jacob D.; Flora, Holley M.; Horner, John R.; Organ, Chris L.

    2016-01-01

    Rugose projections on the anterior and posterior aspects of vertebral neural spines appear throughout Amniota and result from the mineralization of the supraspinous and interspinous ligaments via metaplasia, the process of permanent tissue-type transformation. In mammals, this metaplasia is generally pathological or stress induced, but is a normal part of development in some clades of birds. Such structures, though phylogenetically sporadic, appear throughout the fossil record of non-avian theropod dinosaurs, yet their physiological and adaptive significance has remained unexamined. Here we show novel histologic and phylogenetic evidence that neural spine projections were a physiological response to biomechanical stress in large-bodied theropod species. Metaplastic projections also appear to vary between immature and mature individuals of the same species, with immature animals either lacking them or exhibiting smaller projections, supporting the hypothesis that these structures develop through ontogeny as a result of increasing bending stress subjected to the spinal column. Metaplastic mineralization of spinal ligaments would likely affect the flexibility of the spinal column, increasing passive support for body weight. A stiff spinal column would also provide biomechanical support for the primary hip flexors and, therefore, may have played a role in locomotor efficiency and mobility in large-bodied species. This new association of interspinal ligament metaplasia in Theropoda with large body size contributes additional insight to our understanding of the diverse biomechanical coping mechanisms developed throughout Dinosauria, and stresses the significance of phylogenetic methods when testing for biological trends, evolutionary or not. PMID:27442509

  12. Vertebral Adaptations to Large Body Size in Theropod Dinosaurs.

    Directory of Open Access Journals (Sweden)

    John P Wilson

    Full Text Available Rugose projections on the anterior and posterior aspects of vertebral neural spines appear throughout Amniota and result from the mineralization of the supraspinous and interspinous ligaments via metaplasia, the process of permanent tissue-type transformation. In mammals, this metaplasia is generally pathological or stress induced, but is a normal part of development in some clades of birds. Such structures, though phylogenetically sporadic, appear throughout the fossil record of non-avian theropod dinosaurs, yet their physiological and adaptive significance has remained unexamined. Here we show novel histologic and phylogenetic evidence that neural spine projections were a physiological response to biomechanical stress in large-bodied theropod species. Metaplastic projections also appear to vary between immature and mature individuals of the same species, with immature animals either lacking them or exhibiting smaller projections, supporting the hypothesis that these structures develop through ontogeny as a result of increasing bending stress subjected to the spinal column. Metaplastic mineralization of spinal ligaments would likely affect the flexibility of the spinal column, increasing passive support for body weight. A stiff spinal column would also provide biomechanical support for the primary hip flexors and, therefore, may have played a role in locomotor efficiency and mobility in large-bodied species. This new association of interspinal ligament metaplasia in Theropoda with large body size contributes additional insight to our understanding of the diverse biomechanical coping mechanisms developed throughout Dinosauria, and stresses the significance of phylogenetic methods when testing for biological trends, evolutionary or not.

  13. Vertebral Adaptations to Large Body Size in Theropod Dinosaurs.

    Science.gov (United States)

    Wilson, John P; Woodruff, D Cary; Gardner, Jacob D; Flora, Holley M; Horner, John R; Organ, Chris L

    2016-01-01

    Rugose projections on the anterior and posterior aspects of vertebral neural spines appear throughout Amniota and result from the mineralization of the supraspinous and interspinous ligaments via metaplasia, the process of permanent tissue-type transformation. In mammals, this metaplasia is generally pathological or stress induced, but is a normal part of development in some clades of birds. Such structures, though phylogenetically sporadic, appear throughout the fossil record of non-avian theropod dinosaurs, yet their physiological and adaptive significance has remained unexamined. Here we show novel histologic and phylogenetic evidence that neural spine projections were a physiological response to biomechanical stress in large-bodied theropod species. Metaplastic projections also appear to vary between immature and mature individuals of the same species, with immature animals either lacking them or exhibiting smaller projections, supporting the hypothesis that these structures develop through ontogeny as a result of increasing bending stress subjected to the spinal column. Metaplastic mineralization of spinal ligaments would likely affect the flexibility of the spinal column, increasing passive support for body weight. A stiff spinal column would also provide biomechanical support for the primary hip flexors and, therefore, may have played a role in locomotor efficiency and mobility in large-bodied species. This new association of interspinal ligament metaplasia in Theropoda with large body size contributes additional insight to our understanding of the diverse biomechanical coping mechanisms developed throughout Dinosauria, and stresses the significance of phylogenetic methods when testing for biological trends, evolutionary or not.

  14. Multifrequency sensing of large-sized dielectric boards

    Science.gov (United States)

    Volgyi, Ferenc

    2000-07-01

    After introducing some possibilities and related problems of microwave moisture measurements, a non-destructive testing method of large-sized dielectric boards is shown, which is based on a microwave free-space/double transmission/reflection type two-parameter complex vector measurement. Unlike this basic idea, a 5.8 GHz monitoring system was developed, which is used for moisture content measurement and quality forecast of particleboards continuously, before mechanical testing would be accomplished. Recalling some basic equations, the calculation of Kasa's circles, dry wood basic weight, complex permittivity values, absolute moisture content and mechanical properties of composite boards, also are shown. Low cost MMICs, self-designed microstrip antennas and passive detector/backscatters are used in the instrumentation for the realization of the concept.

  15. An alternative method for determining particle-size distribution of forest road aggregate and soil with large-sized particles

    Science.gov (United States)

    Hakjun Rhee; Randy B. Foltz; James L. Fridley; Finn Krogstad; Deborah S. Page-Dumroese

    2014-01-01

    Measurement of particle-size distribution (PSD) of soil with large-sized particles (e.g., 25.4 mm diameter) requires a large sample and numerous particle-size analyses (PSAs). A new method is needed that would reduce time, effort, and cost for PSAs of the soil and aggregate material with large-sized particles. We evaluated a nested method for sampling and PSA by...

  16. Processing and properties of large-sized ceramic slabs

    Directory of Open Access Journals (Sweden)

    Fossa, L.

    2010-10-01

    Full Text Available Large-sized ceramic slabs – with dimensions up to 360x120 cm2 and thickness down to 2 mm – are manufactured through an innovative ceramic process, starting from porcelain stoneware formulations and involving wet ball milling, spray drying, die-less slow-rate pressing, a single stage of fast drying-firing, and finishing (trimming, assembling of ceramic-fiberglass composites. Fired and unfired industrial slabs were selected and characterized from the technological, compositional (XRF, XRD and microstructural (SEM viewpoints. Semi-finished products exhibit a remarkable microstructural uniformity and stability in a rather wide window of firing schedules. The phase composition and compact microstructure of fired slabs are very similar to those of porcelain stoneware tiles. The values of water absorption, bulk density, closed porosity, functional performances as well as mechanical and tribological properties conform to the top quality range of porcelain stoneware tiles. However, the large size coupled with low thickness bestow on the slab a certain degree of flexibility, which is emphasized in ceramic-fiberglass composites. These outstanding performances make the large-sized slabs suitable to be used in novel applications: building and construction (new floorings without dismantling the previous paving, ventilated façades, tunnel coverings, insulating panelling, indoor furnitures (table tops, doors, support for photovoltaic ceramic panels.

    Se han fabricado piezas de gran formato, con dimensiones de hasta 360x120 cm, y menos de 2 mm, de espesor, empleando métodos innovadores de fabricación, partiendo de composiciones de gres porcelánico y utilizando, molienda con bolas por vía húmeda, atomización, prensado a baja velocidad sin boquilla de extrusión, secado y cocción rápido en una sola etapa, y un acabado que incluye la adhesión de fibra de vidrio al soporte cerámico y el rectificado de la pieza final. Se han

  17. IBAR: Interacting boson model calculations for large system sizes

    Science.gov (United States)

    Casperson, R. J.

    2012-04-01

    Scaling the system size of the interacting boson model-1 (IBM-1) into the realm of hundreds of bosons has many interesting applications in the field of nuclear structure, most notably quantum phase transitions in nuclei. We introduce IBAR, a new software package for calculating the eigenvalues and eigenvectors of the IBM-1 Hamiltonian, for large numbers of bosons. Energies and wavefunctions of the nuclear states, as well as transition strengths between them, are calculated using these values. Numerical errors in the recursive calculation of reduced matrix elements of the d-boson creation operator are reduced by using an arbitrary precision mathematical library. This software has been tested for up to 1000 bosons using comparisons to analytic expressions. Comparisons have also been made to the code PHINT for smaller system sizes. Catalogue identifier: AELI_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AELI_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: GNU General Public License version 3 No. of lines in distributed program, including test data, etc.: 28 734 No. of bytes in distributed program, including test data, etc.: 4 104 467 Distribution format: tar.gz Programming language: C++ Computer: Any computer system with a C++ compiler Operating system: Tested under Linux RAM: 150 MB for 1000 boson calculations with angular momenta of up to L=4 Classification: 17.18, 17.20 External routines: ARPACK (http://www.caam.rice.edu/software/ARPACK/) Nature of problem: Construction and diagonalization of large Hamiltonian matrices, using reduced matrix elements of the d-boson creation operator. Solution method: Reduced matrix elements of the d-boson creation operator have been stored in data files at machine precision, after being recursively calculated with higher than machine precision. The Hamiltonian matrix is calculated and diagonalized, and the requested transition strengths are calculated

  18. Influence of container size, location, and time of day on oviposition patterns of the dengue vector, Aedes aegypti, in Thailand.

    Science.gov (United States)

    Harrington, L C; Ponlawat, A; Edman, J D; Scott, T W; Vermeylen, F

    2008-06-01

    We conducted a study to determine the effect of container size and location on oviposition site selection by Ae. aegypti in large outdoor field enclosures (10 x 10 x 4 m high). There was a strong positive relationship between increasing container diameter, container volume, and water surface area with egg numbers over both high (rainy, July) and low (cool-dry, January) dengue transmission seasons. Location of containers (indoors versus immediately outdoors and underneath houses) did not influence the number of eggs deposited for containers 5-32 cm in diameter in either season. No trends based on container color (black, brown, or grey) were observed. A slight trend with a greater numbers of eggs laid outdoors in the largest containers (42 cm diameter) during the dry season was observed. Three separate models were run using the mixed model procedure in SAS for each container attribute. Controlling for season, time, and date, the most important container attribute predicting total egg numbers was container volume (total capacity) explaining 88% of the variation, followed by water surface area (85%), and container diameter opening (83%). Oviposition peaked in the afternoon at 1600 hrs and 2000 hrs in the dry and rainy seasons, respectively. Few eggs were laid overnight (2000 hrs-0600 hrs). Our results indicate that physical attributes of oviposition sites, such as size, light-dark contrasts, and specular reflectance from water surfaces, play a significant role in oviposition site selection.

  19. Status of the Cherenkov Telescope Array's Large Size Telescopes

    CERN Document Server

    Cortina, J

    2015-01-01

    The Cherenkov Telescope Array (CTA) observatory, will be deployed over two sites in the two hemispheres. Both sites will be equipped with four Large Size Telescopes (LSTs), which are crucial to achieve the science goals of CTA in the 20-200 GeV energy range. Each LST is equipped with a primary tessellated mirror dish of 23 m diameter, supported by a structure made mainly of carbon fibre reinforced plastic tubes and aluminum joints. This solution guarantees light weight (around 100 tons), essential for fast repositioning to any position in the sky in <20 seconds. The camera is composed of 1855 PMTs and embeds the control, readout and trigger electronics. The detailed design is now complete and production of the first LST, which will serve as a prototype for the remaining seven, is well underway. In 2016 the first LST will be installed at the Roque de los Muchachos Observatory on the Canary island of La Palma (Spain). In this talk we will outline the technical solutions adopted to fulfill the design requirem...

  20. Economic Cost-Analysis of the Impact of Container Size on Transplanted Tree Value

    Directory of Open Access Journals (Sweden)

    Lauren M. Garcia Chance

    2017-04-01

    Full Text Available The benefits and costs of varying container sizes have yet to be fully evaluated to determine which container size affords the most advantageous opportunity for consumers. To determine value of the tree following transplant, clonal replicates of Vitex agnus-castus L. [Chaste Tree], Acer rubrum L. var. drummondii (Hook. & Arn. ex Nutt. Sarg. [Drummond Red Maple], and Taxodium distichum (L. Rich. [Baldcypress] were grown under common conditions in each of five container sizes 3.5, 11.7, 23.3, 97.8 or 175.0 L, respectively (#1, 3, 7, 25 or 45. In June 2013, six trees of each container size and species were transplanted to a sandy clay loam field in College Station, Texas. To determine the increase in value over a two-year post-transplant period, height and caliper measurements were taken at the end of nursery production and again at the end of the second growing season in the field, October 2014. Utilizing industry standards, initial costs of materials and labor were then compared with the size of trees after two years. Replacement cost analysis after two growing seasons indicated a greater increase in value for 11.7 and 23.3 L trees compared to losses in value for some 175.0 L trees. In comparison with trees from larger containers, trees from smaller size containers experienced shorter establishment times and increased growth rates, thus creating a quicker return on investment for trees transplanted from the smaller container sizes.

  1. Evolution of large body size in abalones (Haliotis): Patterns and implications

    Science.gov (United States)

    Estes, J.A.; Lindberg, D.R.; Wray, C.

    2005-01-01

    Kelps and other fleshy macroalgae - dominant reef-inhabiting organisms in cool - seasmay have radiated extensively following late Cenozoic polar cooling, thus triggering a chain of evolutionary change in the trophic ecology of nearshore temperate ecosystems. We explore this hypothesis through an analysis of body size in the abalones (Gastropoda; Haliotidae), a widely distributed group in modern oceans that displays a broad range of body sizes and contains fossil representatives from the late Cretaceous (60-75 Ma). Geographic analysis of maximum shell length in living abalones showed that small-bodied species, while most common in the Tropics, have a cosmopolitan distribution, whereas large-bodied species occur exclusively in cold-water ecosystems dominated by kelps and other macroalgae. The phylogeography of body size evolution in extant abalones was assessed by constructing a molecular phylogeny in a mix of large and small species obtained from different regions of the world. This analysis demonstrates that small body size is the plesiomorphic state and largeness has likely arisen at least twice. Finally, we compiled data on shell length from the fossil record to determine how (slowly or suddenly) and when large body size arose in the abalones. These data indicate that large body size appears suddenly at the Miocene/Pliocene boundary. Our findings support the view that fleshy-algal dominated ecosystems radiated rapidly in the coastal oceans with the onset of the most recent glacial age. We conclude with a discussion of the broader implications of this change. ?? 2005 The Paleontological Society. All rights reserved.

  2. Efficient Scheme for Implementing Large Size Signed Multipliers Using Multigranular Embedded DSP Blocks in FPGAs

    Directory of Open Access Journals (Sweden)

    Shuli Gao

    2009-01-01

    Full Text Available Modern FPGAs contain embedded DSP blocks, which can be configured as multipliers with more than one possible size. FPGA-based designs using these multigranular embedded blocks become more challenging when high speed and reduced area utilization are required. This paper proposes an efficient design methodology for implementing large size signed multipliers using multigranular small embedded blocks. The proposed approach has been implemented and tested targeting Altera's Stratix II FPGAs with the aid of the Quartus II software tool. The implementations of the multipliers have been carried out for operands with sizes ranging from 40 to 256 bits. Experimental results demonstrated that our design approach has outperformed the standard scheme used by Quartus II tool in terms of speed and area. On average, the delay reduction is about 20.7% and the area saving, in terms of ALUTs, is about 67.6%.

  3. Large-Scale Containment Cooler Performance Experiments under Accident Conditions

    Directory of Open Access Journals (Sweden)

    Ralf Kapulla

    2012-01-01

    Full Text Available Computational Fluid Dynamics codes are increasingly used to simulate containment conditions after various transient accident scenarios. This paper presents validation experiments, conducted in the frame of the OECD/SETH-2 project. These experiments address the combined effects of mass sources and heat sinks related to gas mixing and hydrogen transport within containment compartments. A wall jet interacts with an operating containment cooler located in the middle (M-configuration and the top (T-configuration of the containment vessel. The experiments are characterized by a 3-phase injection scenario. In Phase I, pure steam is injected, while in Phase II, a helium-steam mixture is injected. Finally, in Phase III, pure steam is injected again. Results for the M-configuration show helium stratification build up during Phase II. During Phase III, a positively buoyant plume emerging from the cooler housing becomes negatively buoyant once it reaches the helium-steam layer and continuously erodes the layer. For the M-configuration, a strong degradation of the cooler performance was observed during the injection of the helium/steam mixture (Phase II. For the T-configuration, we observe a mainly downwards acting cooler resulting in a combination of forced and natural convection flow patterns. The cooler performance degradation was much weaker compared with the M-configuration and a good mixing was ensured by the operation of the cooler.

  4. Containment of Solid Wastes in some Large Scandinavian Cities

    DEFF Research Database (Denmark)

    Du-Thinh, Kien

    1998-01-01

    Two kinds of containment of solid wastes - one in the vicinity of Copenhagen, the capital of Denmark, another on the outskirts of Gothenburg, the second largest city of sweden - are reviewed in this article. They represent two different approaches to waste management. Special attention is given t...

  5. Flow behaviour of emulsions containing small and large droplets

    Energy Technology Data Exchange (ETDEWEB)

    Pal, R. [Waterloo Univ., ON (Canada)

    1997-12-31

    Steady flow and visco-elastic properties of kerosene-in-water and mineral oil-in-water emulsions were studied using a controlled-stress rheometer. Results showed that the viscosity, storage and loss moduli of kerosene-in-water and mineral oil-in-water increase substantially when droplet size is reduced. The emulsion became more elastic and shear-thinning. The minimum in viscosity occurs only at low shear stresses in both kerosene-in-water and mineral oil-in-water emulsions. 59 refs., 2 tabs., 8 figs.

  6. Vibration Analysis of Digital Radiography System for Large Container Inspection

    Institute of Scientific and Technical Information of China (English)

    黄松岭; 李路明; 周立业; 向新程; 安继刚

    2003-01-01

    The cantilever vibration characteristics of a digital radiography system were analyzed to predict the effect of vibration on the performance of a mobile container inspection system. The static deformation,vibration mode and natural frequency of the cantilever of the digital radiography system were calculated with the ALGOR Finite Element System to verify the strength and rigidity of the cantilever. The maximum amplitude of the cantilever vibration occurs as it starts accelerating. The predictions show good agreement with test results, indicating that the finite element model of the cantilever structure accurately models the mechanical characteristics.

  7. Bacterial delivery of large intact genomic-DNA-containing BACs into mammalian cells.

    Science.gov (United States)

    Cheung, Wing; Kotzamanis, George; Abdulrazzak, Hassan; Goussard, Sylvie; Kaname, Tadashi; Kotsinas, Athanassios; Gorgoulis, Vassilis G; Grillot-Courvalin, Catherine; Huxley, Clare

    2012-01-01

    Efficient delivery of large intact vectors into mammalian cells remains problematical. Here we evaluate delivery by bacterial invasion of two large BACs of more than 150 kb in size into various cells. First, we determined the effect of several drugs on bacterial delivery of a small plasmid into different cell lines. Most drugs tested resulted in a marginal increase of the overall efficiency of delivery in only some cell lines, except the lysosomotropic drug chloroquine, which was found to increase the efficiency of delivery by 6-fold in B16F10 cells. Bacterial invasion was found to be significantly advantageous compared with lipofection in delivering large intact BACs into mouse cells, resulting in 100% of clones containing intact DNA. Furthermore, evaluation of expression of the human hypoxanthine phosphoribosyltransferase (HPRT) gene from its genomic locus, which was present in one of the BACs, showed that single copy integrations of the HPRT-containing BAC had occurred in mouse B16F10 cells and that expression of HPRT from each human copy was 0.33 times as much as from each endogenous mouse copy. These data provide new evidence that bacterial delivery is a convenient and efficient method to transfer large intact therapeutic genes into mammalian cells.

  8. Bacterial delivery of large intact genomic-DNA-containing BACs into mammalian cells

    Science.gov (United States)

    Cheung, Wing; Kotzamanis, George; Abdulrazzak, Hassan; Goussard, Sylvie; Kaname, Tadashi; Kotsinas, Athanassios; Gorgoulis, Vassilis G.; Grillot-Courvalin, Catherine; Huxley, Clare

    2012-01-01

    Efficient delivery of large intact vectors into mammalian cells remains problematical. Here we evaluate delivery by bacterial invasion of two large BACs of more than 150 kb in size into various cells. First, we determined the effect of several drugs on bacterial delivery of a small plasmid into different cell lines. Most drugs tested resulted in a marginal increase of the overall efficiency of delivery in only some cell lines, except the lysosomotropic drug chloroquine, which was found to increase the efficiency of delivery by 6-fold in B16F10 cells. Bacterial invasion was found to be significantly advantageous compared with lipofection in delivering large intact BACs into mouse cells, resulting in 100% of clones containing intact DNA. Furthermore, evaluation of expression of the human hypoxanthine phosphoribosyltransferase (HPRT) gene from its genomic locus, which was present in one of the BACs, showed that single copy integrations of the HPRT-containing BAC had occurred in mouse B16F10 cells and that expression of HPRT from each human copy was 0.33 times as much as from each endogenous mouse copy. These data provide new evidence that bacterial delivery is a convenient and efficient method to transfer large intact therapeutic genes into mammalian cells. PMID:22095052

  9. Large-sized condoms challenge theory that "one size fits all".

    Science.gov (United States)

    1989-04-01

    Mentor Corporation and Mayer Laboratories are 2 US condom manufacturers which recently have added large-sized condoms to their product lines in response to complaints from consumers that condoms are too small. Mentor's latex condom, "Magnum," measures 20-25% larger than the average condom. Mayer's "Maxx" condom is 2.3 inches at its widest part at the tip and 8.27 inches long, including the reservoir tip. Dr. Katherine Forrest, consultant to Mayer, suggests that one is less likely to have problems with condoms falling off than one might think. If a condom does not roll all the way down, the extra unrolled latex at the bottom of the condom provides additional support. Thus, even if the condom is a little too wide at the top, the condom will stay on the penis because of the extra support and tightness at the base of the penis. Both Maxx and Magnum are manufactured in Japan. Neither has nonoxynol-9 spermicide, but both Mentor and Mayer plan to add the spermicide to the condoms later this year. The retail cost of the Maxx condom from Mayer is $7.99 for 12; Mentor's Magnum condom costs $7.19 for 12.

  10. Aedes albopictus (Diptera: Culicidae) Oviposition Preference as Influenced by Container Size and Buddleja davidii Plants.

    Science.gov (United States)

    Davis, Timothy J; Kline, Daniel L; Kaufman, Phillip E

    2016-03-01

    Aedes albopictus (Skuse) is a container-breeding mosquito commonly found in residential areas of its range in the United States. Mosquitoes are known to utilize flowering plants for sugar acquisition. Limited information is known about the influences on oviposition site selection, outside of container size. Residential areas are often landscaped with a variety of flowering plants and are known to provide numerous sizes of potential larval developmental sites for container-breeding mosqutioes. Through screened enclosure and field studies, the oviposition preference of Ae. albopictus for containers of three selected sizes (473, 946 and 1,892 ml) and the influence of flowering butterfly bush (Buddleja davidii Franchett cultivar 'Guinevere') plants were examined. Our results document that significantly more eggs were oviposited in the largest containers. Additionally, significantly more eggs were oviposited in containers adjacent to flowering butterfly bushes than in those without a flowering butterfly bush. Finally, our results document that flowering butterfly bushes exerted greater influence over Ae. albopictus oviposition decisions than did container size. Our findings can be applied to several aspects of Ae. albopictus surveillance and control.

  11. Cerium dioxide with large particle size prepared by continuous precipitation

    Institute of Scientific and Technical Information of China (English)

    李梅; 王觅堂; 柳召刚; 胡艳宏; 吴锦绣

    2009-01-01

    Cerium dioxide(CeO2) has attracted much attention and has wide applications such as automotive exhaust catalysts,polishing materials for optical glasses and additives for advanced glasses,as well as cosmetic materials.The particle size and its distribution are key factors to the performance of the materials in the functional applications.However,control of particle size is still a challenge in materials synthesis.Therefore,continuous precipitation of cerium oxalate(precursor of ceria) was carried out at dif...

  12. Enhancement in ionic conductivity on solid polymer electrolytes containing large conducting species

    Energy Technology Data Exchange (ETDEWEB)

    Praveen, D. [Department of Physics, Amrita Viswha Vidyapeetham, Bangalore, India, E-mail: d-praveen@blr.amrita.edu (India); Damle, Ramakrishna [Department of Physics, Bangalore University, Bangalore, India. E-mail: ramkrishnadamle@bub.ernet.in (India)

    2016-05-23

    Solid Polymer Electrolytes (SPEs) lack better conducting properties at ambient temperatures. Various methods to enhance their ionic conductivity like irradiation with swift heavy ions, γ-rays, swift electrons and quenching at low temperature etc., have been explored in the literature. Among these, one of the oldest methods is incorporation of different conducting species into the polymer matrix and/or addition of nano-sized inert particles into SPEs. Various new salts like LiBr, Mg(ClO{sub 4}){sub 2}, NH{sub 4}I etc., have already been tried in the past with some success. Also various nanoparticles like Al{sub 2}O{sub 3}, TiO{sub 2} etc., have been tried in the past. In this article, we have investigated an SPE containing Rubidium as a conducting species. Rubidium has a larger ionic size compared to lithium and sodium ions which have been investigated in the recent past. In the present article, we have investigated the conductivity of large sized conducting species and shown the enhancement in the ionic conductivity by addition of nano-sized inert particles.

  13. Enhancement in ionic conductivity on solid polymer electrolytes containing large conducting species

    Science.gov (United States)

    Praveen, D.; Damle, Ramakrishna

    2016-05-01

    Solid Polymer Electrolytes (SPEs) lack better conducting properties at ambient temperatures. Various methods to enhance their ionic conductivity like irradiation with swift heavy ions, γ-rays, swift electrons and quenching at low temperature etc., have been explored in the literature. Among these, one of the oldest methods is incorporation of different conducting species into the polymer matrix and/or addition of nano-sized inert particles into SPEs. Various new salts like LiBr, Mg(ClO4)2, NH4I etc., have already been tried in the past with some success. Also various nanoparticles like Al2O3, TiO2 etc., have been tried in the past. In this article, we have investigated an SPE containing Rubidium as a conducting species. Rubidium has a larger ionic size compared to lithium and sodium ions which have been investigated in the recent past. In the present article, we have investigated the conductivity of large sized conducting species and shown the enhancement in the ionic conductivity by addition of nano-sized inert particles.

  14. [Impact of particle size and morphology on zinc cation adsorption by hydroxyapatite and dentifrice containing hydroxyapatite].

    Science.gov (United States)

    Yang, Jian-Zhen; Shen, Xiao-Qing; Liu, Cheng-Xia; Xu, Ping-Ping

    2016-05-01

    To study the influence of particle size and morphology on zinc cation adsorption by hydroxyapatite (HA) and dentifrice containing HA. Four HAs with different particle sizes and morphologies, HA-containing dentifrice and blank dentifrice were prepared into suspensions of serial concentrations. Zinc ion solutions with an initial concentration of 10 mg/L was mixed with the suspensions and kept for 24 h for adsorption reaction. The zinc ion concentration in the supernatant was measured by inductively coupled plasma emission spectrometer and the sorption rate of zinc ion was calculated. HA and HA-containing dentifrice with various particle sizes and morphologies were all capable of absorbing zinc ions from simulated waste water, and the adsorption rate of HA-containing dentifrice was 3%-10% higher than that of HA. HA with a particle size of 12 µm and a spherical morphology showed the strongest adsorption ability, followed by short bar-shaped HA with a particle size of 30 µm. Both Langmuir and Freundlich equation could simulate the sorption processes of HA dentifrice, while only Langmuir equation could simulate the sorption processes of HA. Incorporation of HA in dentifrice can enhance zinc ion adsorption capacity of the material. The particle size and morphology of HA both affect the adsorption of zinc ions, and 12-µm HA particle with a spherical morphology has the best adsorption ability.

  15. Radial particle-size segregation during packing of particulates into cylindrical containers

    Science.gov (United States)

    Ripple, C.D.; James, R.V.; Rubin, J.

    1973-01-01

    In a series of experiments, soil materials were placed in long cylindrical containers, using various packing procedures. Soil columns produced by deposition and simultaneous vibratory compaction were dense and axially uniform, but showed significant radial segregation of particle sizes. Similar results were obtained with deposition and simultaneous impact-type compaction when the impacts resulted in significant container "bouncing". The latter procedure, modified to minimize "bouncing" produced dense, uniform soil columns, showing little radial particle-size segregation. Other procedures tested (deposition alone and deposition followed by compaction) did not result in radial segregation, but produced columns showing either relatively low or axially nonuniform densities. Current data suggest that radial particle-size segregation is mainly due to vibration-induced particle circulation in which particles of various sizes have different circulation rates and paths. ?? 1973.

  16. PorcineLEM domain-containing 3:Molecular cloning, functional characterization, and polymorphism associated with ear size

    Institute of Scientific and Technical Information of China (English)

    LIANG Jing; SHI Hui-bi; ZHANG Qin; WANGLi-xian; LI Na; ZHANG Long-chao; WANGLi-gang; LIU Xin; ZHAO Ke-bin; YAN Hua; PU Lei; ZHANG Yue-bo

    2016-01-01

    Ear size exhibits remarkable diversity in pig breeds.LEM domain-containing 3 (LEMD3) on chromosome 5 is considered as an important candidate for porcine ear size. This is the ifrst study on cloning and characterization ofLEMD3 cDNA. The complete cDNA contains 4843 bp, including a 2736-bp open reading frame (ORF), a 37-bp 5´-untranslated region (UTR) and a 2070-bp 3´-UTR. The completeLEMD3 gene is 126241-bp and contains 13 exons and 12 introns. The ORF encodes a deduced LEMD3 protein of 911 amino acids, which shares 82–94% nucleic acid and 51–96% amino acid identity with other species. A phylogenetic tree constructed based on the amino acid sequences revealed that the porcine LEMD3 protein was closely related with cattle LEMD3. Resequencing of the ORF and promoter ofLEMD3 from Minzhu pig and Large White revealed three single nucleotide polymorphisms (SNPs): L964C>A in the complete coding region, L4625A>G in the 3´ UTR, and L-394T>C in the promoter region. Genome-wide association study (GWAS) revealed that al of SNPs were shown signiifcant association with ear size in Large White×Minzhu pig intercross population. With conditional GWAS, –log10(P-value) decreased by more than 80% when each of three SNPs was included as a ifxed effect. These results suggested direct involvement ofLEMD3 or close linkage to the causative mutation for ear size. The ifndings of this study might form the basis for understanding the genetic mechanism of ear size variation in pigs and provide potential molecular markers for screening ear size diversity in pig breeds.

  17. Development of large and medium size biogas plants

    Energy Technology Data Exchange (ETDEWEB)

    Kejun Yang; Datong Zhang [Chengdu Biogas Research Inst. (China)

    2000-07-01

    Anaerobic wastewater treatment has expanded from a few (scraped sludge, animal manure, distillery wastewater and the wastewater from slaughter houses) to more than 200 kinds of wastewaters from several industries such as pharmacy, food, and chemicals. According to incomplete statistics, up to now more than 2,000 large and medium-scale biogas plants have been constructed. They provide biogas to 54,000 households as daily fuel. About 300 biogas power stations have been installed. (orig.)

  18. Oligomeric viral proteins: small in size, large in presence

    Science.gov (United States)

    Jayaraman, Bhargavi; Smith, Amber M.; Fernandes, Jason D.; Frankel, Alan D.

    2016-01-01

    Viruses are obligate parasites that rely heavily on host cellular processes for replication. The small number of proteins typically encoded by a virus is faced with selection pressures that lead to the evolution of distinctive structural properties, allowing each protein to maintain its function under constraints such as small genome size, high mutation rate, and rapidly changing fitness conditions. One common strategy for this evolution is to utilize small building blocks to generate protein oligomers that assemble in multiple ways, thereby diversifying protein function and regulation. In this review, we discuss specific cases that illustrate how oligomerization is used to generate a single defined functional state, to modulate activity via different oligomeric states, or to generate multiple functional forms via different oligomeric states. PMID:27685368

  19. Large Scale Behavior and Droplet Size Distributions in Crude Oil Jets and Plumes

    Science.gov (United States)

    Katz, Joseph; Murphy, David; Morra, David

    2013-11-01

    The 2010 Deepwater Horizon blowout introduced several million barrels of crude oil into the Gulf of Mexico. Injected initially as a turbulent jet containing crude oil and gas, the spill caused formation of a subsurface plume stretching for tens of miles. The behavior of such buoyant multiphase plumes depends on several factors, such as the oil droplet and bubble size distributions, current speed, and ambient stratification. While large droplets quickly rise to the surface, fine ones together with entrained seawater form intrusion layers. Many elements of the physics of droplet formation by an immiscible turbulent jet and their resulting size distribution have not been elucidated, but are known to be significantly influenced by the addition of dispersants, which vary the Weber Number by orders of magnitude. We present experimental high speed visualizations of turbulent jets of sweet petroleum crude oil (MC 252) premixed with Corexit 9500A dispersant at various dispersant to oil ratios. Observations were conducted in a 0.9 m × 0.9 m × 2.5 m towing tank, where large-scale behavior of the jet, both stationary and towed at various speeds to simulate cross-flow, have been recorded at high speed. Preliminary data on oil droplet size and spatial distributions were also measured using a videoscope and pulsed light sheet. Sponsored by Gulf of Mexico Research Initiative (GoMRI).

  20. Size and shape controllable preparation of graphene sponge by freezing, lyophilizing and reducing in container

    Institute of Scientific and Technical Information of China (English)

    ZHAO LianQin; YU BaoWei; ZHANG XiaoLiang; WU RuiHan; LIU XiaoYang; LIAO Rong; YANG ShengTao

    2016-01-01

    Graphene sponge (GS) is a porous 3D structure of graphene.Although hydrothermal reduction,chemical vapor deposition,solution reduction and high temperature annealing could be used for the preparation of GS,the size and shape cannot be well controlled.Herein,we reported a facile method to prepare GS under mild condition in a size and shape controllable way.Graphene oxide was lyophilized to form the spongy structure and reduced by steamy hydrazine hydrate to produce GS.The size and shape of GS prepared were nearly identical to that of the container.The reduction degree of GS could be regulated by the reduction temperature and time.

  1. Genic regions of a large salamander genome contain long introns and novel genes

    Directory of Open Access Journals (Sweden)

    Bryant Susan V

    2009-01-01

    Full Text Available Abstract Background The basis of genome size variation remains an outstanding question because DNA sequence data are lacking for organisms with large genomes. Sixteen BAC clones from the Mexican axolotl (Ambystoma mexicanum: c-value = 32 × 109 bp were isolated and sequenced to characterize the structure of genic regions. Results Annotation of genes within BACs showed that axolotl introns are on average 10× longer than orthologous vertebrate introns and they are predicted to contain more functional elements, including miRNAs and snoRNAs. Loci were discovered within BACs for two novel EST transcripts that are differentially expressed during spinal cord regeneration and skin metamorphosis. Unexpectedly, a third novel gene was also discovered while manually annotating BACs. Analysis of human-axolotl protein-coding sequences suggests there are 2% more lineage specific genes in the axolotl genome than the human genome, but the great majority (86% of genes between axolotl and human are predicted to be 1:1 orthologs. Considering that axolotl genes are on average 5× larger than human genes, the genic component of the salamander genome is estimated to be incredibly large, approximately 2.8 gigabases! Conclusion This study shows that a large salamander genome has a correspondingly large genic component, primarily because genes have incredibly long introns. These intronic sequences may harbor novel coding and non-coding sequences that regulate biological processes that are unique to salamanders.

  2. A scenarios study on future demands on container and truck sizes of the future

    NARCIS (Netherlands)

    Jansen, Jan; Kraaijenhagen, B.; Graser, H.; Szylar, I.; Weijers, Stef

    2012-01-01

    To what extent will future demands of worldwide operating parties, regarding the (tertiary) packaging of their freight flows, determine or influence the future dimensions of freight trucks? That is the question we address to in this paper. In this study we have studied what container sizes may fit i

  3. Aerodynamic Limits on Large Civil Tiltrotor Sizing and Efficiency

    Science.gov (United States)

    Acree, C W., Jr.

    2014-01-01

    The NASA Large Civil Tiltrotor (2nd generation, or LCTR2) has been the reference design for avariety of NASA studies of design optimization, engine and gearbox technology, handling qualities, andother areas, with contributions from NASA Ames, Glenn and Langley Centers, plus academic and industrystudies. Ongoing work includes airfoil design, 3D blade optimization, engine technology studies, andwingrotor aerodynamic interference. The proposed paper will bring the design up to date with the latestresults of such studies, then explore the limits of what aerodynamic improvements might hope toaccomplish. The purpose is two-fold: 1) determine where future technology studies might have the greatestpayoff, and 2) establish a stronger basis of comparison for studies of other vehicle configurations andmissions.

  4. Folding and unfolding of large-size shell construction for application in Earth orbit

    Science.gov (United States)

    Kondyurin, Alexey; Pestrenina, Irena; Pestrenin, Valery; Rusakov, Sergey

    2016-07-01

    A future exploration of space requires a technology of large module for biological, technological, logistic and other applications in Earth orbits [1-3]. This report describes the possibility of using large-sized shell structures deployable in space. Structure is delivered to the orbit in the spaceship container. The shell is folded for the transportation. The shell material is either rigid plastic or multilayer prepreg comprising rigid reinforcements (such as reinforcing fibers). The unfolding process (bringing a construction to the unfolded state by loading the internal pressure) needs be considered at the presence of both stretching and bending deformations. An analysis of the deployment conditions (the minimum internal pressure bringing a construction from the folded state to the unfolded state) of large laminated CFRP shell structures is formulated in this report. Solution of this mechanics of deformable solids (MDS) problem of the shell structure is based on the following assumptions: the shell is made of components whose median surface has a reamer; in the separate structural element relaxed state (not stressed and not deformed) its median surface coincides with its reamer (this assumption allows choose the relaxed state of the structure correctly); structural elements are joined (sewn together) by a seam that does not resist rotation around the tangent to the seam line. The ways of large shell structures folding, whose median surface has a reamer, are suggested. Unfolding of cylindrical, conical (full and truncated cones), and large-size composite shells (cylinder-cones, cones-cones) is considered. These results show that the unfolding pressure of such large-size structures (0.01-0.2 atm.) is comparable to the deploying pressure of pneumatic parts (0.001-0.1 atm.) [3]. It would be possible to extend this approach to investigate the unfolding process of large-sized shells with ruled median surface or for non-developable surfaces. This research was

  5. Pore size distribution, strength, and microstructure of portland cement paste containing metal hydroxide waste

    Energy Technology Data Exchange (ETDEWEB)

    Majid, Z.A.; Mahmud, H.; Shaaban, M.G.

    1996-12-31

    Stabilization/solidification of hazardous wastes is used to convert hazardous metal hydroxide waste sludge into a solid mass with better handling properties. This study investigated the pore size development of ordinary portland cement pastes containing metal hydroxide waste sludge and rice husk ash using mercury intrusion porosimetry. The effects of acre and the addition of rice husk ash on pore size development and strength were studied. It was found that the pore structures of mixes changed significantly with curing acre. The pore size shifted from 1,204 to 324 {angstrom} for 3-day old cement paste, and from 956 to 263 {angstrom} for a 7-day old sample. A reduction in pore size distribution for different curing ages was also observed in the other mixtures. From this limited study, no conclusion could be made as to any correlation between strength development and porosity. 10 refs., 6 figs., 3 tabs.

  6. Size exclusion chromatography (XIII): Identification and quantitation of silicon hydride containing oligomeric components of Sylgard prepolymers. [Polydimethylsiloxane

    Energy Technology Data Exchange (ETDEWEB)

    Kohn, E.; Chisum, M.E.; Moore, K.L.

    1987-12-01

    Methods for the identification and quantitation of oligomeric, silicon hydride (SiH), containing components of Sylgard prepolymers (polydimethylsiloxane: PDMS) have been developed. They employ a combination of size exclusion chromatography (SEC), with infrared (ir) and differential refractometer (DR) detection and gas chromatography/mass spectrometry (GC/MS) verification. The identified oligomers were present at about 20% of total prepolymer and contained from one to six SiH linkages per molecule. Such lower molecular weight oligomers may contribute to the vapor pressure of resins prepared from the prepolymers since they may contain a significant number of molecules which have only one or two SiH groups and are not capable of forming large polymeric structures. 5 refs., 8 figs., 2 tabs.

  7. Study of droplet size and velocity of fuel containing CO2 spray by means of PDA

    Institute of Scientific and Technical Information of China (English)

    XIAO Jin; QIAO Xinqi; HUANG Zhen; FANG Junhua

    2004-01-01

    Injection of fuel containing CO2 has potential to reduce NOx and soot emissions in a diesel engine. This paper presents an experimental study on the spray characteristics of fuel containing CO2 as measured by phase doppler anemometry (PDA). Experiments were performed under atmospheric conditions on diesel hole-type nozzles at constant injection pressure. Effects of CO2 concentration in diesel fuel on the spray pattern, droplet size and velocity were measured. Experimental results show that fuel atomization will improve greatly when the concentration of dissolved CO2 in the fuel exceeds the critical value. The axial and radial velocity of the fuel spray containing CO2 is larger than that of conventional diesel fuel spray near the nozzle exit due to flash boiling phenomena. Downstream of the spray, the radial velocity and droplet size of fuel containing CO2 is much more uniform and smaller than that of pure diesel spray. It is attributed to the greatly enhanced liquid-gas mixing resulting from flash separation of CO2 from the liquid. New insight into the atomization of the fuel containing CO2 was obtained and a possible mechanism to explain the phenomena was proposed. The method may be developed into a new technique for controlling diesel combustion and exhaust emissions.

  8. Preparation of ceria with large particle size and high appearance density

    Institute of Scientific and Technical Information of China (English)

    WANG Songling; LIU Junyun; JIA Jiangtao; LIAO Chunsheng; YAN Chunhua

    2008-01-01

    Cerium is one of the most abundant rare earth dements in both bastnasite and monazite. Ceria has been widely used in optical catalytic, electrolyte, and sensor materials, with unique performances. With the development of functional materials, great interest has been focused on the synthesis and characterization of specific fine/mesoporous ceria powder. In this study, the modified precipitation and recrystallization processes combined with a controlled calcination process for fabricating the ceria with large particle size and high appearance density was reported. During precipitation, a certain amount of mineral acid such as nitric acid served as an additive, to adjust the precipitation and crystallization processes of cerium oxalates. An appropriate acidic condition could lead the process into the Oswald ripening stage and made the particles become bigger. Thus, the appearance density of powder was increased. The optimized conditions, such as the temperature, feeding speed, type and concentration of mineral acids, and the concentration of cerium-contained stock solution, were investigated and evaluated.

  9. Containment Depressurization Capabilities of Filtered Venting System in 1000 MWe PWR with Large Dry Containment

    Directory of Open Access Journals (Sweden)

    Sang-Won Lee

    2014-01-01

    Full Text Available After the Fukushima Daiichi nuclear power plant accident, the Korean government and nuclear industries performed comprehensive safety inspections on all domestic nuclear power plants against beyond design bases events. As a result, a total of 50 recommendations were defined as safety improvement action items. One of them is installation of a containment filtered venting system (CFVS or portable backup containment spray system. In this paper, the applicability of CFVS is examined for OPR1000, a 1000 MWe PWR with large dry containment in Korea. Thermohydraulic analysis results show that a filtered discharge flow rate of 15 [kg/s] at 0.9 [MPa] is sufficient to depressurize the containment against representative containment overpressurization scenarios. Radiological release to the environment is reduced to 10-3 considering the decontamination factor. Also, this cyclic venting strategy reduces noble gas release by 50% for 7 days. The probability of maintaining the containment integrity in level 2 probabilistic safety assessment (PSA initiating events is improved twofold, from 43% to 87%. So, the CFVS can further improve the containment integrity in severe accident conditions.

  10. Composition and particle size of electrolytic copper powders prepared in water-containing dimethyl sulfoxide electrolytes

    Science.gov (United States)

    Mamyrbekova, Aigul'; Abzhalov, B. S.; Mamyrbekova, Aizhan

    2017-07-01

    The possibility of the electroprecipitation of copper powder via the cathodic reduction of an electrolyte solution containing copper(II) nitrate trihydrate and dimethyl sulfoxide (DMSO) is shown. The effect electrolysis conditions (current density, concentration and temperature of electrolyte) have on the dimensional characteristics of copper powder is studied. The size and shape of the particles of the powders were determined by means of electron microscopy; the qualitative composition of the powders, with X-ray diffraction.

  11. Computer Simulation of the Process of Quenching Large-Size Parts in Water and Aqueous Solutions

    Institute of Scientific and Technical Information of China (English)

    N.I.Kobasko; W.S.Morhuniuk; V.V.Dobrivecher; A.M.Weinov

    2004-01-01

    The article presents results of the computer simulation of quenching large-size parts in water and aqueous solutions. It has been shown that the main attention should be paid to eliminating film boiling and providing uniform cooling at the surface of the part to be quenched. Simplified formulas for calculating the optimal time of cooling large-size steel parts are presented.

  12. Experimental investigation and numerical simulation of large-sized aluminum tube extrusion forming

    Institute of Scientific and Technical Information of China (English)

    吕亚臣; 骆俊廷; 马春荣; 徐岩

    2008-01-01

    Large-sized aluminum tube has big section effect, aspect ratio and thin thickness, so that the extrusion technology is complex and the large specific pressure is generated in extrusion cavity. The temperature variation and velocity effect is difficult to control. The extrusion forming of large-sized aluminum tube was researched and simulated. Three-dimensional thermo-mechanical coupled finite element model was constructed and appropriate boundary conditions were given out. The results show that large-sized aluminum tube can be formed by isothermal extrusion through controlling the extrusion velocity and founding the relationship between extrusion velocity and extrusion temperature.

  13. Optical properties of polysiloxane hybrid thin films containing nano-sized Ag-As-Se chalcogenide clusters

    Science.gov (United States)

    Zha, Congji; Osvath, Peter; Wilson, Gerry; Launikonis, Anton

    2009-02-01

    Chalcogenide glasses are attractive for all-optical signal processing due to their outstanding optical properties, including large optical nonlinearity, a high refractive index and high photosensitivity. In device fabrication, a challenge lies in the difficulty of obtaining thin films with a high stability and good uniformity. In this paper, optical thin films containing nano-sized chalcogenide clusters in polysiloxane matrices are fabricated by a modified plasma deposition process. The optical absorption and luminescence emission properties of the hybrid thin films were characterized by UV-Vis-NIR and fluorescence spectroscopy. Luminescent emission from Ag-As-Se nano-sized clusters was observed for the first time in these nano-hybrid thin films, and the mechanism was discussed.

  14. Use of large bulls to improve the body weight of local small sized buffalo

    Directory of Open Access Journals (Sweden)

    M. Van Sanh

    2010-02-01

    Full Text Available Eight Swamp buffalo bulls (4 large and 4 local small sized and 240 buffalo cows (120 selected and 120 non-selected were used to evaluate the effects of bull size and selected cows on body weight of calves. Experimental animals were allocated into 4 groups: T1- large sized bulls x selected cows (BSB+SC; T2 - large sized bulls x non-selected cows (BSB+NSC; T3 – local small sized bulls x selected cows (SSB+SC and CT – local small sized bulls x non-selected cows (SSB+NSC as a control group. Each bull was mated with 15 selected cows and 15 non-selected cows. Body weight of calves at birth, 3, 6, 12 and 24 months of ages was highest in calves of T1, then T2 and then T3 while the lowest weight was found in the CT group. Calf weight in the large sized bulls and selected cows group was higher by 10-15% than that of calves in the local small bulls and non-selected cows group at all ages. It is concluded that the use of large sized bulls for breeding increased body weight of calves. Using large bulls and selected buffalo cows was the best solution for improving the body weight of the local buffalo.

  15. Coronary calcium scores are systematically underestimated at a large chest size : A multivendor phantom study

    NARCIS (Netherlands)

    Willemink, Martin J.; Abramiuc, Bronislaw; den Harder, Annemarie M.; van der Werf, Niels R.; de Jong, Pim A.; Budde, Ricardo P. J.; Wildberger, Joachim E.; Vliegenthart, Rozemarijn; Willems, Tineke P.; Greuter, Marcel J. W.; Leiner, Tim

    2015-01-01

    Objective: To evaluate the effect of chest size on coronary calcium score (CCS) as assessed with new-generation CT systems from 4 major vendors. Methods: An anthropomorphic, small-sized (300 x 200 mm) chest phantom containing 100 small calcifications (diameters, 0.5-2.0 mm) was evaluated with and wi

  16. Genome-wide patterns of large-size presence/absence variants in sorghum

    Institute of Scientific and Technical Information of China (English)

    LiMin Zhang; Hong Luo; ZhiQuan Liu; Yi Zhao; JingChu Luo; DongYun Hao; HaiChun Jing

    2014-01-01

    The presence/absence variants (PAVs) are a major source of genome structural variation and have profound effects on phenotypic and genomic variation in animals and humans. However, little is understood about PAVs in plant genomes. Our previous resequencing effort on three sorghum (Sorghum bicolour L.) genomes, each 12? coverage, uncovered 5 364 PAVs. Here, we report a detailed characterization of 51 large-size (>30 kb) PAVs. These PAVs spanned a total size of 2.92 Mb of the sorghum genome containing 202 known and predicted genes, including 38 genes annotated to encode celldeath and stress response genes. The PAVs varied considerably for repeat sequences and mobile elements with DNA trans-posons as the major components. The frequency and distribution of these PAVs differed substantial y across 96 sorghum inbred lines, and the low-and high frequency PAVs differed in their gene categories. This report shed new light on the occurrence and diversity of PAVs in sorghum genomes. Our research exemplifies a new perspective to explore genome structural variation for genetic improvement in plant breeding.

  17. Flow adjustment inside large finite-size wind farms approaching the infinite wind farm regime

    Science.gov (United States)

    Wu, Ka Ling; Porté-Agel, Fernando

    2017-04-01

    Due to the increasing number and the growing size of wind farms, the distance among them continues to decrease. Thus, it is necessary to understand how these large finite-size wind farms and their wakes could interfere the atmospheric boundary layer (ABL) dynamics and adjacent wind farms. Fully-developed flow inside wind farms has been extensively studied through numerical simulations of infinite wind farms. The transportation of momentum and energy is only vertical and the advection of them is neglected in these infinite wind farms. However, less attention has been paid to examine the length of wind farms required to reach such asymptotic regime and the ABL dynamics in the leading and trailing edges of the large finite-size wind farms. Large eddy simulations are performed in this study to investigate the flow adjustment inside large finite-size wind farms in conventionally-neutral boundary layer with the effect of Coriolis force and free-atmosphere stratification from 1 to 5 K/km. For the large finite-size wind farms considered in the present work, when the potential temperature lapse rate is 5 K/km, the wind farms exceed the height of the ABL by two orders of magnitude for the incoming flow inside the farms to approach the fully-developed regime. An entrance fetch of approximately 40 times of the ABL height is also required for such flow adjustment. At the fully-developed flow regime of the large finite-size wind farms, the flow characteristics match those of infinite wind farms even though they have different adjustment length scales. The role of advection at the entrance and exit regions of the large finite-size wind farms is also examined. The interaction between the internal boundary layer developed above the large finite-size wind farms and the ABL under different potential temperature lapse rates are compared. It is shown that the potential temperature lapse rate plays a role in whether the flow inside the large finite-size wind farms adjusts to the fully

  18. Numerical simulation of radioisotope's dependency on containment performance for large dry PWR containment under severe accidents

    Energy Technology Data Exchange (ETDEWEB)

    Mehboob, Khurram, E-mail: khurramhrbeu@gmail.com [College of Nuclear Science and Technology, Harbin Engineering University, 145-31 Nantong Street, Nangang District, Harbin, Heilongjiang 150001 (China); Xinrong, Cao [College of Nuclear Science and Technology, Harbin Engineering University, 145-31 Nantong Street, Nangang District, Harbin, Heilongjiang 150001 (China); Ahmed, Raheel [College of Automation, Harbin Engineering University, 145-31 Nantong Street, Nangang District, Harbin, Heilongjiang 150001 (China); Ali, Majid [College of Nuclear Science and Technology, Harbin Engineering University, 145-31 Nantong Street, Nangang District, Harbin, Heilongjiang 150001 (China)

    2013-09-15

    Highlights: • Calculation and comparison of activity of BURN-UP code with ORIGEN2 code. • Development of SASTC computer code. • Radioisotopes dependency on containment ESFs. • Mitigation in atmospheric release with ESFs operation. • Variation in radioisotopes source term with spray flow and pH value. -- Abstract: During the core melt accidents large amount of fission products can be released into the containment building. These fission products escape into the environment to contribute in accident source term. The mitigation in environmental release is demanded for such radiological consequences. Thus, countermeasures to source term, mitigations of release of radioactivity have been studied for 1000 MWe PWR reactor. The procedure of study is divided into five steps: (1) calculation and verification of core inventory, evaluated by BURN-UP code, (2) containment modeling based on radioactivity removal factors, (3) selection of potential accidents initiates the severe accident, (4) calculation of release of radioactivity, (5) study the dependency of release of radioactivity on containment engineering safety features (ESFs) inducing mitigation. Loss of coolant accident (LOCA), small break LOCA and flow blockage accidents (FBA) are selected as initiating accidents. The mitigation effect of ESFs on source term has been studied against ESFs performance. Parametric study of release of radioactivity has been carried out by modeling and simulating the containment parameters in MATLAB, which takes BURN-UP outcomes as input along with the probabilistic data. The dependency of iodine and aerosol source term on boric and caustic acid spray has been determined. The variation in source term mitigation with the variation of containment spray flow rate and pH values have been studied. The variation in containment retention factor (CRF) has also been studied with the ESF performance. A rapid decrease in source term is observed with the increase in pH value.

  19. Online Aerosol Mass Spectrometry of Single Micrometer-Sized Particles Containing Poly(ethylene glycol)

    Energy Technology Data Exchange (ETDEWEB)

    Bogan, M J; Patton, E; Srivastava, A; Martin, S; Fergenson, D; Steele, P; Tobias, H; Gard, E; Frank, M

    2006-10-25

    Analysis of poly(ethylene glycol)(PEG)-containing particles by online single particle aerosol mass spectrometers equipped with laser desorption ionization (LDI) is reported. We demonstrate that PEG-containing particles are useful in the development of aerosol mass spectrometers because of their ease of preparation, low cost, and inherently recognizable mass spectra. Solutions containing millimolar quantities of PEGs were nebulized and, after drying, the resultant micrometer-sized PEG containing particles were sampled. LDI (266 nm) of particles containing NaCl and PEG molecules of average molecular weight <500 generated mass spectra reminiscent of mass spectra of PEG collected by other MS schemes including the characteristic distribution of positive ions (Na{sup +} adducts) separated by the 44 Da of the ethylene oxide units separating each degree of polymerization. PEGs of average molecular weight >500 were detected from particles that also contained t the tripeptide tyrosine-tyrosine-tyrosine or 2,5-dihydroxybenzoic acid, which were added to nebulized solutions to act as matrices to assist LDI using pulsed 266 nm and 355 nm lasers, respectively. Experiments were performed on two aerosol mass spectrometers, one reflectron and one linear, that each utilize two time-of-flight mass analyzers to detect positive and negative ions created from a single particle. PEG-containing particles are currently being employed in the optimization of our bioaerosol mass spectrometers for the application of measurements of complex biological samples, including human effluents, and we recommend that the same strategies will be of great utility to the development of any online aerosol LDI mass spectrometer platform.

  20. Estimates of Radiation Dose Rates Near Large Diameter Sludge Containers in T Plant

    CERN Document Server

    Himes, D A

    2002-01-01

    Dose rates in T Plant canyon during the handling and storage of large diameter storage containers of K Basin sludge were estimated. A number of different geometries were considered from which most operational situations of interest can be constructed.

  1. Electrochemical corrosion behavior of Cu-40Ni-20Cr alloys with different grain sizes in solutions containing chloride ions

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The electrochemical corrosion behavior of the two Cu-40Ni-20Cr alloys prepared by conventional casting(CA) and mechanical alloying(MA) with the different grain sizes was studied by using open-circuit potential(OCP), potentiodynamic polarization and electrochemical impedance spectroscopy(EIS) methods in solutions containing chloride ions. The results show that the free corrosion potentials of the two alloys move towards negative values, corrosion currents increase and therefore corrosion rates become faster with the increase of chloride ion concentrations. EIS plots of CACu-40Ni-20Cr alloy are composed of single capacitive loop, while EIS plots of MACu-40Ni-20Cr alloy are composed of double capacitive loops in solution containing lower chloride ion concentrations. EIS plots of the two alloys have Warburg impedance with the increase of chloride ion concentrations.Corrosion rates of MACu-40Ni-20Cr alloy become faster than those of CACu-40Ni-20Cr alloy obviously in solutions containing the same chloride ion concentrations because MACu-40Ni-20Cr alloy is able to produce large concentrations of grain boundaries in the course of reduction in grain size by mechanical alloying.

  2. Community Structure in Large Networks: Natural Cluster Sizes and the Absence of Large Well-Defined Clusters

    CERN Document Server

    Leskovec, Jure; Dasgupta, Anirban; Mahoney, Michael W

    2008-01-01

    A large body of work has been devoted to defining and identifying clusters or communities in social and information networks. We explore from a novel perspective several questions related to identifying meaningful communities in large social and information networks, and we come to several striking conclusions. We employ approximation algorithms for the graph partitioning problem to characterize as a function of size the statistical and structural properties of partitions of graphs that could plausibly be interpreted as communities. In particular, we define the network community profile plot, which characterizes the "best" possible community--according to the conductance measure--over a wide range of size scales. We study over 100 large real-world social and information networks. Our results suggest a significantly more refined picture of community structure in large networks than has been appreciated previously. In particular, we observe tight communities that are barely connected to the rest of the network ...

  3. Structural, Dynamical, and Electronic Transport Properties of Modified DNA Duplexes Containing Size-Expanded Nucleobases

    Energy Technology Data Exchange (ETDEWEB)

    Fuentes-Cabrera, Miguel A [ORNL; Orozco, Modesto [Institut de Recerca Biomedica, Parc Cientific de Barcelona, Barcelona, Spain; Luque, Javier [Universitat de Barcelona; Sumpter, Bobby G [ORNL; Blas, Jose [Universidad de Castilla-La Mancha; Ordejon, Pablo J [ORNL; Huertas, Oscar [Universitat de Barcelona; Tabares, Carolina [Universitat de Barcelona

    2011-01-01

    Among the distinct strategies proposed to expand the genetic alphabet, sizeexpanded nucleobases are promising for the development of modified DNA duplexes with improved biotechnological properties. In particular, duplexes built up by replacing canonical bases with the corresponding benzo-fused counterparts could be valuable as molecular nanowires. In this context, this study reports the results of classical molecular dynamics simulations carried out to examine the structural and dynamical features of size-expanded DNAs, including both hybrid duplexes containing mixed pairs of natural and benzo-fused bases (xDNA) and pure size-expanded (xxDNA) duplexes. Furthermore, the electronic structure of both natural and size-expanded duplexes is examined by means of density functional computations. The results confirm that the structural and flexibility properties of the canonical DNA are globally little affected by the presence of benzo-fused bases. Themost relevant differences are found in the enhanced size of the grooves, and the reduction in the twist. However, the analysis also reveals subtle structural effects related to the nature and sequence of benzo-fused bases in the duplex. On the other hand, electronic structure calculations performed for xxDNAs confirm the reduction in the HOMOLUMO gap predicted from the analysis of the natural bases and their size-expanded counterparts, which suggests that pure size-expanded DNAs can be good conductors. A more complex situation is found for xDNAs, where fluctuations in the electrostatic interaction between base pairs exerts a decisive influence on the modulation of the energy gap.

  4. Modeling the Effect of Climate Change on Large Fire Size, Counts, and Intensities Using the Large Fire Simulator (FSim)

    Science.gov (United States)

    Riley, K. L.; Haas, J. R.; Finney, M.; Abatzoglou, J. T.

    2013-12-01

    Changes in climate can be expected to cause changes in wildfire activity due to a combination of shifts in weather (temperature, precipitation, relative humidity, wind speed and direction) and vegetation. Changes in vegetation could include type conversions, altered forest structure, and shifts in species composition, the effects of which could be mitigated or exacerbated by management activities. Further, changes in suppression response and effectiveness may alter potential wildfire activity, as well as the consequences of wildfire. Feedbacks among these factors are extremely complex and uncertain. The ability to anticipate changes driven by fire weather (largely outside of human control) can lead to development of fire and fuel management strategies aimed at mitigating current and future risk. Therefore, in this study we focus on isolating the effects of climate-induced changes in weather on wildfire activity. Specifically, we investigated the effect of changes in weather on fire activity in the Canadian Rockies ecoregion, which encompasses Glacier National Park and several large wilderness areas to the south. To model the ignition, growth, and containment of wildfires, we used the Large Fire Simulator (FSim), which we coupled with current and projected future climatic conditions. Weather streams were based on data from 14 downscaled Global Circulation Models (GCMs) from the Coupled Model Intercomparison Project Phase 5 (CMIP5) using the Representative Concentration Pathways (RCP) 45 and 85 for the years 2040-2060. While all GCMs indicate increases in temperature for this area, which would be expected to exacerbate fire activity, precipitation predictions for the summer wildfire season are more variable, ranging from a decrease of approximately 50 mm to an increase of approximately 50 mm. Windspeeds are generally predicted to decrease, which would reduce rates of spread and fire intensity. The net effect of these weather changes on the size, number, and intensity

  5. Large- and small-size advantages in sneaking behaviour in the dusky frillgoby Bathygobius fuscus

    Science.gov (United States)

    Takegaki, Takeshi; Kaneko, Takashi; Matsumoto, Yukio

    2012-04-01

    Sneaking tactic, a male alternative reproductive tactic involving sperm competition, is generally adopted by small individuals because of its inconspicuousness. However, large size has an advantage when competition occurs between sneakers for fertilization of eggs. Here, we suggest that both large- and small-size advantages of sneaker males are present within the same species. Large sneaker males of the dusky frillgoby Bathygobius fuscus showed a high success rate in intruding into spawning nests because of their advantage in competition among sneaker males in keeping a suitable position to sneak, whereas small sneakers had few chances to sneak. However, small sneaker males were able to stay in the nests longer than large sneaker males when they succeeded in sneak intrusion. This suggests the possibility of an increase in their paternity. The findings of these size-specific behavioural advantages may be important in considering the evolution of size-related reproductive traits.

  6. Small, medium, large or supersize? The development and evaluation of interventions targeted at portion size.

    Science.gov (United States)

    Vermeer, W M; Steenhuis, I H M; Poelman, M P

    2014-07-01

    In the past decades, portion sizes of high-caloric foods and drinks have increased and can be considered an important environmental obesogenic factor. This paper describes a research project in which the feasibility and effectiveness of environmental interventions targeted at portion size was evaluated. The studies that we conducted revealed that portion size labeling, offering a larger variety of portion sizes, and proportional pricing (that is, a comparable price per unit regardless of the size) were considered feasible to implement according to both consumers and point-of-purchase representatives. Studies into the effectiveness of these interventions demonstrated that the impact of portion size labeling on the (intended) consumption of soft drinks was, at most, modest. Furthermore, the introduction of smaller portion sizes of hot meals in worksite cafeterias in addition to the existing size stimulated a moderate number of consumers to replace their large meals by a small meal. Elaborating on these findings, we advocate further research into communication and marketing strategies related to portion size interventions; the development of environmental portion size interventions as well as educational interventions that improve people's ability to deal with a 'super-sized' environment; the implementation of regulation with respect to portion size labeling, and the use of nudges to stimulate consumers to select healthier portion sizes.

  7. Production of large size single transient cavitation bubbles with tube arrest method

    Institute of Scientific and Technical Information of China (English)

    Chen Qi-Dai; Wang Long

    2004-01-01

    Large size single transient cavitation bubbles of maximum diameter up to 3 cm with sonoluminescence have been column motion is proposed. The results of numerical simulation are compared with the experimental data of the bubble size and oscillation period as the key parameters.

  8. The welfare implications of large litter size in the domestic pig I

    DEFF Research Database (Denmark)

    Rutherford, K.M.D.; Baxter, E.M.; D'Eath, R.B.

    2013-01-01

    Increasing litter size has long been a goal of pig breeders and producers, and may have implications for pig (Sus scrofa domesticus) welfare. This paper reviews the scientific evidence on biological factors affecting sow and piglet welfare in relation to large litter size. It is concluded that, i...

  9. The Relative Efficiency of Container Terminals in Small and Medium-Sized Ports in China

    Directory of Open Access Journals (Sweden)

    Zi-Yao Ding

    2015-06-01

    Full Text Available The promotion of domestic consumption in China will gradually ramp up the small and medium-sized port container industry, and this will require greater port efficiency and an updated development strategy. The aim of this paper is to evaluate operational and productivity efficiency change in 21 coastal small and medium sized-port container terminals in China. The first step was carried out using data envelopment analysis (DEA and the Malmquist productivity index (MPI, and the factors affecting productivity efficiency change were then estimated and quantified using Tobit regression. The empirical results indicate that the most efficient terminals are the Rizhao and Lianyungang port terminals. Furthermore, the terminals that hold a share of more than 50% of Chinese state-owned shipping line show the highest increase in productivity efficiency change. Lastly, the results indicate manpower structure; Chinese state-owned shipping line shareholding; registered capital; and shipping routes have positive effect and the factor, number of terminal operators, have a negative correlation.

  10. Intermediate pond sizes contain the highest density, richness, and diversity of pond-breeding amphibians.

    Directory of Open Access Journals (Sweden)

    Raymond D Semlitsch

    Full Text Available We present data on amphibian density, species richness, and diversity from a 7140-ha area consisting of 200 ponds in the Midwestern U.S. that represents most of the possible lentic aquatic breeding habitats common in this region. Our study includes all possible breeding sites with natural and anthropogenic disturbance processes that can be missing from studies where sampling intensity is low, sample area is small, or partial disturbance gradients are sampled. We tested whether pond area was a significant predictor of density, species richness, and diversity of amphibians and if values peaked at intermediate pond areas. We found that in all cases a quadratic model fit our data significantly better than a linear model. Because small ponds have a high probability of pond drying and large ponds have a high probability of fish colonization and accumulation of invertebrate predators, drying and predation may be two mechanisms driving the peak of density and diversity towards intermediate values of pond size. We also found that not all intermediate sized ponds produced many larvae; in fact, some had low amphibian density, richness, and diversity. Further analyses of the subset of ponds represented in the peak of the area distribution showed that fish, hydroperiod, invertebrate density, and canopy are additional factors that drive density, richness and diversity of ponds up or down, when extremely small or large ponds are eliminated. Our results indicate that fishless ponds at intermediate sizes are more diverse, produce more larvae, and have greater potential to recruit juveniles into adult populations of most species sampled. Further, hylid and chorus frogs are found predictably more often in ephemeral ponds whereas bullfrogs, green frogs, and cricket frogs are found most often in permanent ponds with fish. Our data increase understanding of what factors structure and maintain amphibian diversity across large landscapes.

  11. Intermediate pond sizes contain the highest density, richness, and diversity of pond-breeding amphibians.

    Science.gov (United States)

    Semlitsch, Raymond D; Peterman, William E; Anderson, Thomas L; Drake, Dana L; Ousterhout, Brittany H

    2015-01-01

    We present data on amphibian density, species richness, and diversity from a 7140-ha area consisting of 200 ponds in the Midwestern U.S. that represents most of the possible lentic aquatic breeding habitats common in this region. Our study includes all possible breeding sites with natural and anthropogenic disturbance processes that can be missing from studies where sampling intensity is low, sample area is small, or partial disturbance gradients are sampled. We tested whether pond area was a significant predictor of density, species richness, and diversity of amphibians and if values peaked at intermediate pond areas. We found that in all cases a quadratic model fit our data significantly better than a linear model. Because small ponds have a high probability of pond drying and large ponds have a high probability of fish colonization and accumulation of invertebrate predators, drying and predation may be two mechanisms driving the peak of density and diversity towards intermediate values of pond size. We also found that not all intermediate sized ponds produced many larvae; in fact, some had low amphibian density, richness, and diversity. Further analyses of the subset of ponds represented in the peak of the area distribution showed that fish, hydroperiod, invertebrate density, and canopy are additional factors that drive density, richness and diversity of ponds up or down, when extremely small or large ponds are eliminated. Our results indicate that fishless ponds at intermediate sizes are more diverse, produce more larvae, and have greater potential to recruit juveniles into adult populations of most species sampled. Further, hylid and chorus frogs are found predictably more often in ephemeral ponds whereas bullfrogs, green frogs, and cricket frogs are found most often in permanent ponds with fish. Our data increase understanding of what factors structure and maintain amphibian diversity across large landscapes.

  12. Effect of Total Inoculum Size Containing Lactobacillus acidophilus or Lactobacillus casei on Fermentation of Goat Milk

    Directory of Open Access Journals (Sweden)

    He Chen

    2015-02-01

    Full Text Available In order to obtain the optimum inoculum size of goat milk fermented by probiotics, the total inoculum size containing L. acidophilus or L. casei on pH, acidity and viable counts and sensory during fermentation were studied on the basis of S. thermophilus and L. bulgaricus as starter cultures. The results showed as follows: the optimum inoculum size of L. acidophilus or L. casei were all 7% and goat milk was fermented at 39°C for 4.5 h. The pH, acidity, the viable counts of L. acidophilus and the total viable counts were respectively 4.48, 91°T, 1.60×107 cfu/mL and 1.69×109 cfu/mL. The pH, acidity, the viable counts of L. casei and the total viable counts were respectively 4.38, 96°T, 2.80×108 cfu/mL and 2.20×109 cfu/mL.

  13. Behavioural responses of larval container mosquitoes to a size-selective predator.

    Science.gov (United States)

    Kesavaraju, Banugopan; Alto, Barry W; Lounibos, L Philip; Juliano, Steven A

    2007-06-01

    The hypothesis that size-selective predation and species-specific prey behaviours facilitate the coexistence between larvae of invasive Aedes albopictus (Skuse) and U.S.A.-native Ochlerotatus triseriatus (Say) was tested experimentally with the predator Corethrella appendiculata (Grabham).Larval behaviours associated with a higher risk of predation were identified, and prey behavioural responses were tested in either the physical presence of predators or in water containing predation cues. Larvae that thrashed on container bottoms had a higher risk of being captured by fourth instar C. appendiculata than did larvae resting on the water surface. Ochlerotatus triseriatus, but not A. albopictus, adopted low-risk behaviours in response to water-borne cues to predation. Both prey species reduced risky behaviours in the physical presence of the predator, but O. triseriatus showed a stronger response.The vulnerability of 2nd and 3rd instar prey to predation was compared, and behavioural responses were correlated with prey vulnerability. Second instars of both species were more vulnerable to predation by C. appendiculata than were 3rd instars, and the 3rd instar A. albopictus was more vulnerable than O. triseriatus of the same stage. All instars of O. triseriatus showed a similar reduction of risky behaviours in response to the presence of C. appendiculata despite 4th instar prey being relatively invulnerable to size-selective predation.Weaker predator avoidance, coupled with superior competitive ability, of invasive A. albopictus is likely to contribute to its coexistence with O. triseriatus in containers of the south-eastern U.S.A., where C. appendiculata can be abundant.

  14. A wild goose metapneumovirus containing a large attachment glycoprotein is avirulent but immunoprotective in domestic turkeys.

    Science.gov (United States)

    Bennett, Richard S; LaRue, Rebecca; Shaw, Daniel; Yu, Qingzhong; Nagaraja, K V; Halvorson, David A; Njenga, M Kariuki

    2005-12-01

    The genomic structure and composition of an avian metapneumovirus (aMPV) recently isolated from wild Canada geese (goose 15a/01) in the United States, together with its replication, virulence, and immunogenicity in domestic turkeys, were investigated. The sizes of seven of the eight genes, sequence identity, and genome organization of goose aMPV were similar to those of turkey aMPV subtype C (aMPV/C) strains, indicating that it belonged to the subtype. However, the goose virus contained the largest attachment (G) gene of any pneumovirus or metapneumovirus, with the predicted G protein of 585 amino acids (aa) more than twice the sizes of G proteins from other subtype C viruses and human metapneumovirus and more than 170 aa larger than the G proteins from the other aMPV subtypes (subtypes A, B, and D). The large G gene resulted from a 1,015-nucleotide insertion at 18 nucleotides upstream of the termination signal of the turkey aMPV/C G gene. Three other aMPV isolates from Canada geese had similarly large G genes, whereas analysis of recent aMPV strains circulating in U.S. turkeys did not indicate the presence of the goose virus-like strain. In vitro, the goose virus replicated to levels (2 x 10(5) to 5 x 10(5) 50% tissue culture infective dose) comparable to those produced by turkey aMPV/C strains. More importantly, the virus replicated efficiently in the upper respiratory tract of domestic turkeys but with no clinical signs in either day-old or 2-week-old turkeys. The virus was also horizontally transmitted to naïve birds, and turkey infections with goose 15a/01 induced production of aMPV-specific antibodies. Challenging day-old or 2-week-old turkeys vaccinated with live goose aMPV resulted in lower clinical scores in 33% of the birds, whereas the rest of the birds had no detectable clinical signs of the upper respiratory disease, suggesting that the mutant virus may be a safe and effective vaccine against aMPV infection outbreaks in commercial turkeys.

  15. Transient response in longitudinal grain size to reduced sediment supply in a large river

    Science.gov (United States)

    Singer, Michael

    2010-05-01

    -S transition corresponds to the point at which shear stress and sorting decline concomitantly. However, the transition zone contains anomalously high sorting values characterized by fine bedload sheets that are probably associated with vertical river adjustment and fining due to decreases in gravel supply and therefore a relative increase in fine sediment supply from tributaries, bank erosion, and vertical winnowing and incision. This research gives new insight into transient river channel behavior in response to sediment supply. It demonstrates that the position of the G-S transition and the length scale of the transtion from gravel to sand is a function of feedbacks between sediment supply, transport capacity, and hydraulics. Ferguson, R.I., 2003, Emergence of abrupt gravel to sand transitions along rivers through sorting processes: Geology, v. 31, p. 159-162. Paola, C., and Seal, R., 1995, Grain size patchiness as a cause of selective deposition and downstream fining: Water Resources Research, v. 31, p. 1395-1407. Singer, M.B., 2008, Downstream patterns of bed-material grain size in a large, lowland alluvial river subject to low sediment supply: Water Resources Research, v. 44, W12202, doi: 10.1029/2008WR007183. Singer, M.B., and Dunne, T., 2004, Modeling decadal bed-material flux based on stochastic hydrology: Water Resources Research, v. 40, p. W03302, doi: 10.1029/2003WR002723.

  16. Using plate mapping to examine portion size and plate composition for large and small divided plates.

    Science.gov (United States)

    Sharp, David E; Sobal, Jeffery; Wansink, Brian

    2014-12-01

    Does the size of a plate influence the serving of all items equally, or does it influence the serving of some foods - such as meat versus vegetables - differently? To examine this question, we used the new method of plate mapping, where people drew a meal on a paper plate to examine sensitivity to small versus large three-compartment divided plates in portion size and meal composition in a sample of 109 university students. The total drawn meal area was 37% bigger on large plates than small plates, which showed that the portion of plate coverage did not differ by plate size. Men and women drew bigger vegetable portions and men drew bigger meat portions on large plates when compared to small plates. These results suggest that men and women are differentially sensitive to plate size for overall meal size and for meal composition. Implications for decreasing portion size and improving meal balance are that plate size may influence portion size and change the proportions of foods served.

  17. Hydrogen and steam distribution following a small-break LOCA in large dry containment

    Institute of Scientific and Technical Information of China (English)

    DENG Jian; CAO Xuewu

    2007-01-01

    The hydrogen deflagration is one of the major risk contributors to threaten the integrity of the containment in a nuclear power plant, and hydrogen control in the case of severe accidents is required by nuclear regulations.Based on the large dry containment model developed with the integral severe-accident analysis tool, a small-break loss-of-coolant-accident (LOCA) without HPI, LPI, AFW and containment sprays, leading to the core degradation and large hydrogen generation, is calculated. Hydrogen and steam distribution in containment compartments is investigated. The analysis results show that significant hydrogen deflagration risk exits in the reactor coolant pump (RCP)compartment and the cavity during the early period, if no actions are taken to mitigate the effects of hydrogen accumulation.

  18. Enhanced Laser Cooling of Rare-Earth-Ion-Doped Glass Containing Nanometer-Sized Metallic Particles

    Institute of Scientific and Technical Information of China (English)

    JIA You-Hun; ZHONG Biao; YIN Jian-Ping

    2009-01-01

    The enhanced laser cooling performance of rare-earth-ions-doped glasses containing small particles is predicted. This is achieved by the enhancement of local field around rare earth ions, owing to the surface plasmon resonance of small metallic particles. The role of energy transfer between ions and the particle is theoretical discussed. Depending on the particle size and the ion emission quantum efficiency, the enhancement of the absorption and the fluorescence is predicted. Moreover, taking Yb3+-doped ZBLAN as example, the cooling power and heat-light converting efficiency are calculated. It is finally concluded that the absorption and the fluorescence are greatly enhanced in these composite materials, the cooling power is increased compared to the bulk material.

  19. Erbium-doped slot waveguides containing size-controlled silicon nanocrystals

    Energy Technology Data Exchange (ETDEWEB)

    Hoffmann, R.; Beyer, J., E-mail: jan.beyer@physik.tu-freiberg.de; Heitmann, J. [Institute of Applied Physics, TU Bergakademie Freiberg, D-09596 Freiberg (Germany); Klemm, V.; Rafaja, D. [Institute of Materials Science, TU Bergakademie Freiberg, D-09596 Freiberg (Germany); Johnson, B. C.; McCallum, J. C. [Centre for Quantum Computation and Communication Technology, School of Physics, University of Melbourne, Melbourne, Victoria 3010 (Australia)

    2015-04-28

    Silicon based slot waveguides with a slot containing Si nanocrystals (Si-nc) and Erbium ions (Er{sup 3+}) inside a silica matrix were prepared using sputter deposition and low-energy ion implantation. This sequence enabled independent optimization of nanocrystal formation and Er{sup 3+} incorporation parameters. Using a superlattice approach, the size of the Si-nc inside the slot could be controlled and optimized for maximum Er{sup 3+} luminescence yield at 1.54 μm. Er{sup 3+} is found to be efficiently pumped by Si-nc of sizes around 3 to 4 nm. Increasing Er{sup 3+} photoluminescence at 1.54 μm with increasing post-implantation annealing temperatures up to 1000 °C is attributed to annealing of matrix or Si-nc interface defects mainly. Additionally, a dependence of the Er{sup 3+} luminescence intensity on both the excitation and emission linear polarization orientation is shown, which demonstrates efficient field enhancement in sputtered slot waveguide structures.

  20. Container size and growing media affects water use efficiency in a Gerbera jamesonii cut flower crop

    Directory of Open Access Journals (Sweden)

    Libertad Mascarini

    2012-10-01

    Full Text Available Two containers (4 and 8 L plastic pots and three growing media mixture types (0/100, 25/75 and 50/50 % of peat/perlite were used, with the aim of determining the optimum combination for gerbera cut flower crop, considering both commercial productivity (yield and quality of cut flowers and environmental impact, (water and fertilizer use efficiency. The best combination in the first year of production was 8 L and 0/100, followed of 4 and 8 L with the 25/75, with a yield of 53.4, 30.5 and 29.7 flowers m-2 respectively. The yield of the rest of the treatments were similar, around 20 flowers m-2. Commercial cut flower quality was aceptable in all treatments. Considering the efficiency measured as the ratio water used per flower harvested, 8L 0/100 was clearly superior with a value of 1.23 L/flower, the rest of the treatments were between 2.17 y 4.14 L/flower, keeping relation as much with container size like with growing media mixture. The importance of these results is the simultaneous consideration of many factors which affect both comercial profitability and development of sustainable technology for intensive crops.

  1. Salt-assisted direct exfoliation of graphite into high-quality, large-size, few-layer graphene sheets.

    Science.gov (United States)

    Niu, Liyong; Li, Mingjian; Tao, Xiaoming; Xie, Zhuang; Zhou, Xuechang; Raju, Arun P A; Young, Robert J; Zheng, Zijian

    2013-08-21

    We report a facile and low-cost method to directly exfoliate graphite powders into large-size, high-quality, and solution-dispersible few-layer graphene sheets. In this method, aqueous mixtures of graphite and inorganic salts such as NaCl and CuCl2 are stirred, and subsequently dried by evaporation. Finally, the mixture powders are dispersed into an orthogonal organic solvent solution of the salt by low-power and short-time ultrasonication, which exfoliates graphite into few-layer graphene sheets. We find that the as-made graphene sheets contain little oxygen, and 86% of them are 1-5 layers with lateral sizes as large as 210 μm(2). Importantly, the as-made graphene can be readily dispersed into aqueous solution in the presence of surfactant and thus is compatible with various solution-processing techniques towards graphene-based thin film devices.

  2. Aggregates of nisin with various bactoprenol-containing cell wall precursors differ in size and membrane permeation capacity.

    Science.gov (United States)

    Scherer, Katharina; Wiedemann, Imke; Ciobanasu, Corina; Sahl, Hans-Georg; Kubitscheck, Ulrich

    2013-11-01

    Many lantibiotics use the membrane bound cell wall precursor Lipid II as a specific target for killing Gram-positive bacteria. Binding of Lipid II usually impedes cell wall biosynthesis, however, some elongated lantibiotics such as nisin, use Lipid II also as a docking molecule for pore formation in bacterial membranes. Although the unique nisin pore formation can be analyzed in Lipid II-doped vesicles, mechanistic details remain elusive. We used optical sectioning microscopy to directly visualize the interaction of fluorescently labeled nisin with membranes of giant unilamellar vesicles containing Lipid II and its various bactoprenol precursors. We quantitatively analyzed the binding and permeation capacity of nisin when applied at nanomolar concentrations. Specific interactions with Lipid I, Lipid II and bactoprenol-diphosphate (C55-PP), but not bactoprenol-phosphate (C55-P), resulted in the formation of large molecular aggregates. For Lipid II, we demonstrated the presence of both nisin and Lipid II in these aggregates. Membrane permeation induced by nisin was observed in the presence of Lipid I and Lipid II, but not in the presence of C55-PP. Notably, the size of the C55-PP-nisin aggregates was significantly smaller than that of the aggregates formed with Lipid I and Lipid II. We conclude that the membrane permeation capacity of nisin is determined by the size of the bactoprenol-containing aggregates in the membrane. Notably, transmitted light images indicated that the formation of large aggregates led to a pinch-off of small vesicles, a mechanism, which probably limits the growth of aggregates and induces membrane leakage.

  3. Optical encryption for large-sized images using random phase-free method

    CERN Document Server

    Shimobaba, Tomoyoshi; Endo, Yutaka; Hirayama, Ryuji; Hiyama, Daisuke; Hasegawa, Satoki; Nagahama, Yuki; Sano, Marie; Sugie, Takashige; Ito, Tomoyoshi

    2015-01-01

    We propose an optical encryption framework that can encrypt and decrypt large-sized images beyond the size of the encrypted image using our two methods: random phase-free method and scaled diffraction. In order to record the entire image information on the encrypted image, the large-sized images require the random phase to widely diffuse the object light over the encrypted image; however, the random phase gives rise to the speckle noise on the decrypted images, and it may be difficult to recognize the decrypted images. In order to reduce the speckle noise, we apply our random phase-free method to the framework. In addition, we employ scaled diffraction that calculates light propagation between planes with different sizes by changing the sampling rates.

  4. Chemical Vapor Deposition of Large-Size Monolayer MoSe2 Crystals on Molten Glass.

    Science.gov (United States)

    Chen, Jianyi; Zhao, Xiaoxu; Tan, Sherman J R; Xu, Hai; Wu, Bo; Liu, Bo; Fu, Deyi; Fu, Wei; Geng, Dechao; Liu, Yanpeng; Liu, Wei; Tang, Wei; Li, Linjun; Zhou, Wu; Sum, Tze Chien; Loh, Kian Ping

    2017-01-25

    We report the fast growth of high-quality millimeter-size monolayer MoSe2 crystals on molten glass using an ambient pressure CVD system. We found that the isotropic surface of molten glass suppresses nucleation events and greatly improves the growth of large crystalline domains. Triangular monolayer MoSe2 crystals with sizes reaching ∼2.5 mm, and with a room-temperature carrier mobility up to ∼95 cm(2)/(V·s), can be synthesized in 5 min. The method can also be used to synthesize millimeter-size monolayer MoS2 crystals. Our results demonstrate that "liquid-state" glass is a highly promising substrate for the low-cost growth of high-quality large-size 2D transition metal dichalcogenides (TMDs).

  5. A simplified experimental model of large-for-size liver transplantation in pigs

    Directory of Open Access Journals (Sweden)

    Antonio Jose Goncalves Leal

    2013-01-01

    Full Text Available OBJECTIVE: The ideal ratio between liver graft mass and recipient body weight for liver transplantation in small infants is unknown; however, if this ratio is over 4%, a condition called large-for-size may occur. Experimental models of large-for-size liver transplants have not been described in the literature. In addition, orthotopic liver transplantation is marked by high morbidity and mortality rates in animals due to the clamping of the venous splanchnic system. Therefore, the objective of this study was to create a porcine model of large-for-size liver transplantation with clamping of the supraceliac aorta during the anhepatic phase as an alternative to venovenous bypass. METHOD: Fourteen pigs underwent liver transplantation with whole-liver grafts without venovenous bypass and were divided into two experimental groups: the control group, in which the weights of the donors were similar to the weights of the recipients; and the large-for-size group, in which the weights of the donors were nearly 2 times the weights of the recipients. Hemodynamic data, the results of serum biochemical analyses and histological examination of the transplanted livers were collected. RESULTS: The mortality rate in both groups was 16.5% (1/7. The animals in the large-for-size group had increased serum levels of potassium, sodium, aspartate aminotransferase and alanine aminotransferase after graft reperfusion. The histological analyses revealed that there were no significant differences between the groups. CONCLUSION: This transplant method is a feasible experimental model of large-for-size liver transplantation.

  6. Hull Girder Fatigue Damage Estimations of a Large Container Vessel by Spectral Analysis

    DEFF Research Database (Denmark)

    Andersen, Ingrid Marie Vincent; Jensen, Jørgen Juncher

    2013-01-01

    This paper deals with fatigue damage estimation from the analysis of full-scale stress measurements in the hull of a large container vessel (9,400 TEU) covering several months of operation. For onboard decision support and hull monitoring sys-tems, there is a need for a fast reliable method...

  7. Optimum siting and sizing of a large distributed generator in a mesh connected system

    Energy Technology Data Exchange (ETDEWEB)

    Elnashar, Mohab M.; El Shatshat, Ramadan; Salama, Magdy M.A. [Department of Electrical and Computer Engineering, University of Waterloo, Waterloo, Ontario (Canada)

    2010-06-15

    This paper proposes a new approach to optimally determine the appropriate size and location of the distributed generator (DG) in a large mesh connected system. This paper presents a visual optimization approach in which the planner plays an important role in determining the optimal siting and sizing of the DG through the choice of the appropriate weight factors of the parameters included in the optimization technique according to the system deficiencies. Losses, voltage profile and short circuit level are used in the algorithm to determine the optimum sizes and locations of the DG. The short circuit level parameter is introduced to represent the protective device requirements in the selection of the size and location of the DG. The proposed technique has been tested on the IEEE 24 - bus mesh connected test system. The obtained results showed clearly that the optimal size and location can be simply determined through the proposed approach. (author)

  8. Comparison of containment systems for large sodium-cooled breeder reactors

    Energy Technology Data Exchange (ETDEWEB)

    Seeman, S.E.; Armstrong, G.R.

    1978-04-01

    Three types of containment configurations for large breeder reactors (1000 MWe/2500 MWt) were compared to determine characteristic responses of each type to selected hypothetical accident conditions. The three types of system configurations were the single, double and containment-confinement designs. Two types of postulated hypothetical accidents were applied as a basis for evaluation--the energetic core disassambly accident and the whole core melt-through accident. More than 20 separate cases were analyzed in which design and accident assumptions were varied. Based on this study the containment-confinement configuration is shown to be the most promising for limiting off-site radiation doses for large sodium-cooled breeder reactors given the specific assumptions on the initial accident conditions.

  9. Ultrafast laser ablation and machining large-size structures on porcine bone.

    Science.gov (United States)

    An, Ran; Khadar, Ghadeer W; Wilk, Emilia I; Emigh, Brent; Haugen, Harold K; Wohl, Gregory R; Dunlop, Brett; Anvari, Mehran; Hayward, Joseph E; Fang, Qiyin

    2013-07-01

    When using ultrafast laser ablation in some orthopedic applications where precise cutting/drilling is required with minimal damage to collateral tissue, it is challenging to produce large-sized and deep holes using a tightly focused laser beam. The feasibility of producing deep, millimeter-size structures under different ablation strategies is investigated. X-ray computed microtomography was employed to analyze the morphology of these structures. Our results demonstrated the feasibility of producing holes with sizes required in clinical applications using concentric and helical ablation protocols.

  10. Corporate Social Responsibility in Large and Medium-sized Companies in Poland

    Directory of Open Access Journals (Sweden)

    Maja Żychlewicz

    2016-06-01

    Full Text Available The paper aims to confront views on the CSR concept with the actual activities undertaken in this area by the large and medium-sized companies in Poland. The paper is enriched by the presentation of consumer opinions on CSR, by which it is possible to identify the purpose of implementing socially responsible activities in these entities. The thesis of the paper is that large and medium-sized enterprises in Poland recognize the expectations of consumers in the implementation of the concept of corporate social responsibility and at the same time feel the same need, but many of them have not taken any action in this respect so far.

  11. Effects of ischemic preconditioning in a pig model of large-for-size liver transplantation

    Science.gov (United States)

    Leal, Antonio José Gonçalves; Tannuri, Ana Cristina Aoun; Belon, Alessandro Rodrigo; Guimarães, Raimundo Renato Nunes; Coelho, Maria Cecília Mendonça; de Oliveira Gonçalves, Josiane; Serafini, Suellen; de Melo, Evandro Sobroza; Tannuri, Uenis

    2015-01-01

    OBJECTIVE: In most cases of pediatric liver transplantation, the clinical scenario of large-for-size transplants can lead to hepatic dysfunction and a decreased blood supply to the liver graft. The objective of the present experimental investigation was to evaluate the effects of ischemic preconditioning on this clinical entity. METHODS: Eighteen pigs were divided into three groups and underwent liver transplantation: a control group, in which the weights of the donors were similar to those of the recipients, a large-for-size group, and a large-for-size + ischemic preconditioning group. Blood samples were collected from the recipients to evaluate the pH and the sodium, potassium, aspartate aminotransferase and alanine aminotransferase levels. In addition, hepatic tissue was sampled from the recipients for histological evaluation, immunohistochemical analyses to detect hepatocyte apoptosis and proliferation and molecular analyses to evaluate the gene expression of Bax (pro-apoptotic), Bcl-XL (anti-apoptotic), c-Fos and c-Jun (immediate-early genes), ischemia-reperfusion-related inflammatory cytokines (IL-1, TNF-alpha and IL-6, which is also a stimulator of hepatocyte regeneration), intracellular adhesion molecule, endothelial nitric oxide synthase (a mediator of the protective effect of ischemic preconditioning) and TGF-beta (a pro-fibrogenic cytokine). RESULTS: All animals developed acidosis. At 1 hour and 3 hours after reperfusion, the animals in the large-for-size and large-for-size + ischemic preconditioning groups had decreased serum levels of Na and increased serum levels of K and aspartate aminotransferase compared with the control group. The molecular analysis revealed higher expression of the Bax, TNF-alpha, I-CAM and TGF-beta genes in the large-for-size group compared with the control and large-for-size + ischemic preconditioning groups. Ischemic preconditioning was responsible for an increase in c-Fos, IL-1, IL-6 and e-NOS gene expression. CONCLUSION

  12. Effects of ischemic preconditioning in a pig model of large-for-size liver transplantation

    Directory of Open Access Journals (Sweden)

    Antonio José Gonçalves Leal

    2015-02-01

    Full Text Available OBJECTIVE: In most cases of pediatric liver transplantation, the clinical scenario of large-for-size transplants can lead to hepatic dysfunction and a decreased blood supply to the liver graft. The objective of the present experimental investigation was to evaluate the effects of ischemic preconditioning on this clinical entity. METHODS: Eighteen pigs were divided into three groups and underwent liver transplantation: a control group, in which the weights of the donors were similar to those of the recipients, a large-for-size group, and a large-for-size + ischemic preconditioning group. Blood samples were collected from the recipients to evaluate the pH and the sodium, potassium, aspartate aminotransferase and alanine aminotransferase levels. In addition, hepatic tissue was sampled from the recipients for histological evaluation, immunohistochemical analyses to detect hepatocyte apoptosis and proliferation and molecular analyses to evaluate the gene expression of Bax (pro-apoptotic, Bcl-XL (anti-apoptotic, c-Fos and c-Jun (immediate-early genes, ischemia-reperfusion-related inflammatory cytokines (IL-1, TNF-alpha and IL-6, which is also a stimulator of hepatocyte regeneration, intracellular adhesion molecule, endothelial nitric oxide synthase (a mediator of the protective effect of ischemic preconditioning and TGF-beta (a pro-fibrogenic cytokine. RESULTS: All animals developed acidosis. At 1 hour and 3 hours after reperfusion, the animals in the large-for-size and large-for-size + ischemic preconditioning groups had decreased serum levels of Na and increased serum levels of K and aspartate aminotransferase compared with the control group. The molecular analysis revealed higher expression of the Bax, TNF-alpha, I-CAM and TGF-beta genes in the large-for-size group compared with the control and large-for-size + ischemic preconditioning groups. Ischemic preconditioning was responsible for an increase in c-Fos, IL-1, IL-6 and e-NOS gene expression

  13. Embrittlement and decrease of apparent strength in large-sized concrete structures

    Indian Academy of Sciences (India)

    Alberto Carpinteri; Bernardino Chiaia

    2002-08-01

    The problem of scale-effects on the performances of concrete structures is discussed. Experimentally observed decrease of nominal tensile strength, accompanied by structural embrittlement, occurring in large structures is of crucial importance in modern concrete engineering. Most of the previous approaches to the problem are restricted to notched structures and they often fail to predict mechanical behaviour in real situations. The physical approach put forward by us takes into adequate account the effects of microstructural disorder and seems to be valid in the whole size range, at least for unnotched structures. Thereby, reliable predictions can be made of the material properties in large-sized concrete structures.

  14. Synapse clusters are preferentially formed by synapses with large recycling pool sizes.

    Directory of Open Access Journals (Sweden)

    Oliver Welzel

    Full Text Available Synapses are distributed heterogeneously in neural networks. The relationship between the spatial arrangement of synapses and an individual synapse's structural and functional features remains to be elucidated. Here, we examined the influence of the number of adjacent synapses on individual synaptic recycling pool sizes. When measuring the discharge of the styryl dye FM1-43 from electrically stimulated synapses in rat hippocampal tissue cultures, a strong positive correlation between the number of neighbouring synapses and recycling vesicle pool sizes was observed. Accordingly, vesicle-rich synapses were found to preferentially reside next to neighbours with large recycling pool sizes. Although these synapses with large recycling pool sizes were rare, they were densely arranged and thus exhibited a high amount of release per volume. To consolidate these findings, functional terminals were marked by live-cell antibody staining with anti-synaptotagmin-1-cypHer or overexpression of synaptopHluorin. Analysis of synapse distributions in these systems confirmed the results obtained with FM 1-43. Our findings support the idea that clustering of synapses with large recycling pool sizes is a distinct developmental feature of newly formed neural networks and may contribute to functional plasticity.

  15. Effect of large pore size of multifunctional mesoporous microsphere on removal of heavy metal ions.

    Science.gov (United States)

    Yuan, Qing; Li, Nan; Chi, Yue; Geng, Wangchang; Yan, Wenfu; Zhao, Ying; Li, Xiaotian; Dong, Bin

    2013-06-15

    Pore size of mesoporous materials is crucial for their surface grafting. This article develops a novel multifunctional microsphere with a large pore size mesoporous silica shell (ca. 10.3 nm) and a magnetic core (Fe₃O₄), which is fabricated using cetyltrimethylammonium bromide (CTAB) as pore-forming agents, tetraethyl orthosilicate (TEOS) as silicon source through a sol-gel process. Compared with small pore size mesoporous silica magnetic microspheres (ca. 2-4 nm), the large pore size one can graft 447 mg/g amino groups in order to adsorb more heavy metal ions (Pb(2+): 880.6 mg/g, Cu(2+): 628.3mg/g, Cd(2+): 492.4 mg/g). The metal-loaded multifunctional microspheres could be easily removed from aqueous solution by magnetic separation and regenerated easily by acid treatment. The results suggest that the large pore size multifunctional microspheres are potentially useful materials for high effectively adsorbing and removing different heavy metal ions in aqueous solution. Copyright © 2013 Elsevier B.V. All rights reserved.

  16. Electrical transport in transverse direction through silicon carbon alloy multilayers containing regular size silicon quantum dots

    Science.gov (United States)

    Mandal, Aparajita; Kole, Arindam; Dasgupta, Arup; Chaudhuri, Partha

    2016-11-01

    Electrical transport in the transverse direction has been studied through a series of hydrogenated silicon carbon alloy multilayers (SiC-MLs) deposited by plasma enhanced chemical vapor deposition method. Each SiC-ML consists of 30 cycles of the alternating layers of a nearly amorphous silicon carbide (a-SiC:H) and a microcrystalline silicon carbide (μc-SiC:H) that contains high density of silicon quantum dots (Si-QDs). A detailed investigation by cross sectional TEM reveals preferential growth of densely packed Si-QDs of regular sizes ∼4.8 nm in diameter in a vertically aligned columnar structure within the SiC-ML. More than six orders of magnitude increase in transverse current through the SiC-ML structure were observed for decrease in the a-SiC:H layer thickness from 13 nm to 2 nm. The electrical transport mechanism was established to be a combination of grain boundary or band tail hopping and Frenkel-Poole (F-P) type conduction depending on the temperature and externally applied voltage ranges. Evaluation of trap concentration within the multilayer structures from the fitted room temperature current voltage characteristics by F-P function shows reduction up-to two orders of magnitude indicating an improvement in the short range order in the a-SiC:H matrix for decrease in the thickness of a-SiC:H layer.

  17. THE QUALIMETRY OF LARGE-SIZED STAMPED-SHEET DETAILS GEOMETRY

    Directory of Open Access Journals (Sweden)

    A. Demchenko

    2009-01-01

    Full Text Available The qualimetric method of the large-sized stamped-sheet details influence of geometric shape on the manufacture performance characteristics are given. The graphic model of shape classification and geometric shape factor definition algorithms for triangular and quadrangular shapes are proposed.

  18. INSTALLATION FOR LARGE SIZE STAMP HARDENING TRANINIG BY WATER-AIR MIXTURE

    Directory of Open Access Journals (Sweden)

    L. A. Glazkov

    2009-01-01

    Full Text Available The BNTU has developed a technological process for large-size stamp hardening by means of a water-air mixture.  The  basic  requirements  imposed on an hardening  installation using  a  water-air mixture are the following: provision of smooth cooling of a part in order to achieve the required  hardness and structure; possibility of machining parts of various sizes; change of modes for machining parts of various grades of steel according to any hardness rate.The peculiar features of the given installation are: a presence of microprocessor control of water-air mixture supply, possibility of simultaneous machining of a stamp set (2 parts and position change of parts to be hardened in the process of thermal treatment.Installation for large-sized stamp hardening has been manufactured and introduced at theMinskplant of special tools and machining attachments.

  19. Large Time Asymptotics for a Continuous Coagulation-Fragmentation Model with Degenerate Size-Dependent Diffusion

    KAUST Repository

    Desvillettes, Laurent

    2010-01-01

    We study a continuous coagulation-fragmentation model with constant kernels for reacting polymers (see [M. Aizenman and T. Bak, Comm. Math. Phys., 65 (1979), pp. 203-230]). The polymers are set to diffuse within a smooth bounded one-dimensional domain with no-flux boundary conditions. In particular, we consider size-dependent diffusion coefficients, which may degenerate for small and large cluster-sizes. We prove that the entropy-entropy dissipation method applies directly in this inhomogeneous setting. We first show the necessary basic a priori estimates in dimension one, and second we show faster-than-polynomial convergence toward global equilibria for diffusion coefficients which vanish not faster than linearly for large sizes. This extends the previous results of [J.A. Carrillo, L. Desvillettes, and K. Fellner, Comm. Math. Phys., 278 (2008), pp. 433-451], which assumes that the diffusion coefficients are bounded below. © 2009 Society for Industrial and Applied Mathematics.

  20. Potential enhanced ability of giant squid to detect sperm whales is an exaptation tied to their large body size.

    Science.gov (United States)

    Schmitz, Lars; Motani, Ryosuke; Oufiero, Christopher E; Martin, Christopher H; McGee, Matthew D; Wainwright, Peter C

    2013-01-01

    It has been hypothesized that sperm whale predation is the driver of eye size evolution in giant squid. Given that the eyes of giant squid have the size expected for a squid this big, it is likely that any enhanced ability of giant squid to detect whales is an exaptation tied to their body size. Future studies should target the mechanism behind the evolution of large body size, not eye size. Reconstructions of the evolutionary history of selective regime, eye size, optical performance, and body size will improve the understanding of the evolution of large eyes in large ocean animals.

  1. Mathematical Modelling of Nonstationary Physico Chemical Processes in Large Sized SPRM Pyrotechnical Ignition System

    Directory of Open Access Journals (Sweden)

    Alexey M. Lipanov

    1997-10-01

    Full Text Available In this paper, the laws of the unstable wave processes accompanying the combustion abnormal mode in the large-sized solid propellant rocket motor {SPRM pyrotechnical ignition system {IS are investigated by numerical method. The IS contains the main {cylindrical channel (MC having uniform perforation over the lateral surface, The left MC boundary is blocked and the right boundary is uniformly perforated. The whole perforation is hermetically sealed from outside. The additional {cylindrical channel {AC {an initial impulse amplifier with uniform perforation over the lateral surface is installed into the MC cavity, coaxially to MC. The right AC boundary is blocked, and the time-varying high-temperature gas flow, containing incandescent 'particles is supplied from initiator, equipped with a fast burning compound, through AC left perforated boundary. To imitate the exploitation conditions, the IS is placed in cylindrical imitation chamber {imitative SPRM. In a number of cases, before the beginning of the IS operation, a situation can be realised when the pelletised solid propellant {PSP mass is non-uniformly distributed along the IS AC length, and the greater part of the AC lateral perforation is blocked by the PSP inserted in the IS MC. Under these conditions, the effect of abnormal strengthening of the pressure waves at the AC boundaries is possible. For describing the abnormal nonstationary physico-chemical processes, a mathematical model is developed. For the check-up of this complex model, the numerical calculation results have been compared with the results of the fire stand tests for the regular IS and the engine. The numerical analysis of the unstable wave process development in the AC has shown that the rise of the pressure with an ever increasing amplitude is realised at the moment, when a shock wave reflects alternately, on the left and on the right AC boundaries. The effect of the pressure waves' abnormal strengthening can result in the

  2. Large-scale genotyping identifies a new locus at 22q13.2 associated with female breast size.

    Science.gov (United States)

    Li, Jingmei; Foo, Jia Nee; Schoof, Nils; Varghese, Jajini S; Fernandez-Navarro, Pablo; Gierach, Gretchen L; Quek, Swee Tian; Hartman, Mikael; Nord, Silje; Kristensen, Vessela N; Pollán, Marina; Figueroa, Jonine D; Thompson, Deborah J; Li, Yi; Khor, Chiea Chuen; Humphreys, Keith; Liu, Jianjun; Czene, Kamila; Hall, Per

    2013-10-01

    Individual differences in breast size are a conspicuous feature of variation in human females and have been associated with fecundity and advantage in selection of mates. To identify common variants that are associated with breast size, we conducted a large-scale genotyping association meta-analysis in 7169 women of European descent across three independent sample collections with digital or screen film mammograms. The samples consisted of the Swedish KARMA, LIBRO-1 and SASBAC studies genotyped on iCOGS, a custom illumina iSelect genotyping array comprising of 211 155 single nucleotide polymorphisms (SNPs) designed for replication and fine mapping of common and rare variants with relevance to breast, ovary and prostate cancer. Breast size of each subject was ascertained by measuring total breast area (mm(2)) on a mammogram. We confirm genome-wide significant associations at 8p11.23 (rs10086016, p=1.3×10(-14)) and report a new locus at 22q13 (rs5995871, p=3.2×10(-8)). The latter region contains the MKL1 gene, which has been shown to impact endogenous oestrogen receptor α transcriptional activity and is recruited on oestradiol sensitive genes. We also replicated previous genome-wide association study findings for breast size at four other loci. A new locus at 22q13 may be associated with female breast size.

  3. Development of pressure containment and damage tolerance technology for composite fuselage structures in large transport aircraft

    Science.gov (United States)

    Smith, P. J.; Thomson, L. W.; Wilson, R. D.

    1986-01-01

    NASA sponsored composites research and development programs were set in place to develop the critical engineering technologies in large transport aircraft structures. This NASA-Boeing program focused on the critical issues of damage tolerance and pressure containment generic to the fuselage structure of large pressurized aircraft. Skin-stringer and honeycomb sandwich composite fuselage shell designs were evaluated to resolve these issues. Analyses were developed to model the structural response of the fuselage shell designs, and a development test program evaluated the selected design configurations to appropriate load conditions.

  4. Size Reduction Techniques for Large Scale Permanent Magnet Generators in Wind Turbines

    Science.gov (United States)

    Khazdozian, Helena; Hadimani, Ravi; Jiles, David

    2015-03-01

    Increased wind penetration is necessary to reduce U.S. dependence on fossil fuels, combat climate change and increase national energy security. The U.S Department of Energy has recommended large scale and offshore wind turbines to achieve 20% wind electricity generation by 2030. Currently, geared doubly-fed induction generators (DFIGs) are typically employed in the drivetrain for conversion of mechanical to electrical energy. Yet, gearboxes account for the greatest downtime of wind turbines, decreasing reliability and contributing to loss of profit. Direct drive permanent magnet generators (PMGs) offer a reliable alternative to DFIGs by eliminating the gearbox. However, PMGs scale up in size and weight much more rapidly than DFIGs as rated power is increased, presenting significant challenges for large scale wind turbine application. Thus, size reduction techniques are needed for viability of PMGs in large scale wind turbines. Two size reduction techniques are presented. It is demonstrated that 25% size reduction of a 10MW PMG is possible with a high remanence theoretical permanent magnet. Additionally, the use of a Halbach cylinder in an outer rotor PMG is investigated to focus magnetic flux over the rotor surface in order to increase torque. This work was supported by the National Science Foundation under Grant No. 1069283 and a Barbara and James Palmer Endowment at Iowa State University.

  5. Flight and size constraints: hovering performance of large hummingbirds under maximal loading.

    Science.gov (United States)

    Chai, P; Millard, D

    1997-11-01

    As the smallest birds, hummingbirds are the only birds capable of prolonged hovering. This suggests that hovering locomotion scales unfavourably with size. Is the hovering performance of larger hummingbird species more constrained by size than that of smaller ones? Maximal load-lifting capacities of the two largest species of hummingbirds found in the United States, the blue-throated (Lampornis clemenciae, 8.4 g) and magnificent (Eugenes fulgens, 7.4 g) hummingbird, as well as the two other local small species, the black-chinned (Archilochus alexandri, 3.0 g) and rufus (Selasphorus rufus, 3.3 g) hummingbird, were determined under conditions of short-burst performance. The power reserves of hummingbirds are substantial relative to normal hovering performance. The two large species lifted maximal loads close to twice their body mass for a very brief duration of over 0.4 s. The small species lifted maximal loads approximately equal to their own mass with a longer duration of over 0.6 s. For the two large species under maximal loading, estimates of burst muscle mass-specific mechanical power output assuming perfect elastic energy storage averaged 309 W kg-1, compared with 75 W kg-1 during free hovering without loading. For the two small species, these values were 228 W kg-1 and 88 W kg-1, respectively. The differences in aerodynamic force production and power output between the large and small size classes occur despite their similar wing stroke velocity. This indicates that, during burst performance in these hummingbirds, the larger ones had a higher load-lifting capacity and generated more muscle power. In spite of the twofold difference in body mass, both large and small hummingbirds have evolved to become potent aerial competitors in order to exploit their common food resource, nectar. Both size classes have evolved to cope with the multi-dimensional effects of size constraining their aerodynamics, muscle mechanics, metabolism and ecology.

  6. Market size and innovation: An application to the French seed market for large crops

    OpenAIRE

    Charlot, Sylvie; Dridi, Chokri; Lemarié, Stéphane

    2015-01-01

    The aim of this paper is to analyse the impact of market size on innovation in the seed industry. The analysis is based on a panel dataset that covers 19 large crops in France during the period 1989-2012. Our econometric analysis is based on a negative binomial specification and we conduct both cross section as well as panel data analysis. We show that the French crop area always has a positive and significant effect on the number of innovations introduced each year. Market size of foreign co...

  7. Jurisdiction Size and Local Democracy: Evidence on Internal Political Efficacy from Large-scale Municipal Reform

    DEFF Research Database (Denmark)

    Lassen, David Dreyer; Serritzlew, Søren

    2011-01-01

    and problems of endogeneity. We focus on internal political efficacy, a psychological condition that many see as necessary for high-quality participatory democracy. We identify a quasiexperiment, a large-scale municipal reform in Denmark, which allows us to estimate a causal effect of jurisdiction size...... on internal political efficacy. The reform, affecting some municipalities, but not all, was implemented by the central government, and resulted in exogenous, and substantial, changes in municipal population size. Based on survey data collected before and after the reform, we find, using various difference...

  8. 40 CFR 141.81 - Applicability of corrosion control treatment steps to small, medium-size and large water systems.

    Science.gov (United States)

    2010-07-01

    ... treatment steps to small, medium-size and large water systems. 141.81 Section 141.81 Protection of... to small, medium-size and large water systems. (a) Systems shall complete the applicable corrosion...) or (b)(3) of this section. (2) A small system (serving ≤3300 persons) and a medium-size system...

  9. Electrochemical Nanoparticle Sizing Via Nano-Impacts: How Large a Nanoparticle Can be Measured?

    Science.gov (United States)

    Bartlett, Thomas R; Sokolov, Stanislav V; Compton, Richard G

    2015-01-01

    The field of nanoparticle (NP) sizing encompasses a wide array of techniques, with electron microscopy and dynamic light scattering (DLS) having become the established methods for NP quantification; however, these techniques are not always applicable. A new and rapidly developing method that addresses the limitations of these techniques is the electrochemical detection of NPs in solution. The ‘nano-impacts’ technique is an excellent and qualitative in situ method for nanoparticle characterization. Two complementary studies on silver and silver bromide nanoparticles (NPs) were used to assess the large radius limit of the nano-impact method for NP sizing. Noting that by definition a NP cannot be larger than 100 nm in diameter, we have shown that the method quantitatively sizes at the largest limit, the lower limit having been previously reported as ∼6 nm.1 PMID:26491639

  10. Large size austenitic stainless steel forgings for nuclear and cryogenic application - development, manufacturing and properties

    Energy Technology Data Exchange (ETDEWEB)

    Ohnishi, Keizo; Suzuki, Komei; Sato, Ikuo; Murai, Etuso (Japan Steel Works Ltd., Muroran Plant, Hokkaido (Japan))

    1992-01-01

    The high quality one-piece large austenetic stainless steel forgings are required in the several components such as nuclear reactors and run tanks for rocket engine test stand in order to assure the structural integrity and to make it easy to fabricate and inspect the components. When the austenitic stainless steel forgings are increased in size, various problems must be overcome to assure the high quality forgings. The ingot making and hot working play an important role in determining the quality of the products. In such points, the lastest manufacturing techniques such as steel making of large size ingot and hot working to get uniform and fine grains are discussed together with the fundamental data of the material properties. (orig.).

  11. Homogenous Crack-Free Large Size YBCO/YSZ/Sapphire Films for Application

    Science.gov (United States)

    Almog, B.; Azoulay, M.; Deutscher, G.

    2006-09-01

    YBa2Cu3O7-δ (YBCO) films grown on Sapphire are highly suitable for applications. The production of large size (2-3″) homogeneous, thick (d ⩾ 600nm) films of high quality is of major importance. We report the growth of such films using a buffer layer of Yttrium-stabilized ZrO2(YSZ). The films are highly homogeneous and show excellent mechanical properties. They exhibit no sign of cracking even after many thermal cycles. Their critical thickness exceeds 1000nm. However, because of the large lattice mismatch there is a decrease in the electric properties(increases Rs, decreases jc).

  12. Some Problems and Solutions of Applying TBLT in a Chinese Large-sized Class

    Institute of Scientific and Technical Information of China (English)

    周尧

    2014-01-01

    This paper mainly looks into the problems of applying Task-based Language Teaching(TBLT) and possible solutions to them.TBLT is now also widely used in Chinese classrooms.It can also be called as "the Age of Task"(Johnson,2001: P.194).However,there are still some problems when TBLT is applied in China.Most of the problems are caused by the large class size and examination-oriented education in China.

  13. DESIGN AND DEVELOPMENT OF A LARGE SIZE NON-TRACKING SOLAR COOKER

    Directory of Open Access Journals (Sweden)

    N. M. NAHAR

    2009-09-01

    Full Text Available A large size novel non-tracking solar cooker has been designed, developed and tested. The cooker has been designed in such a way that the width to length ratio for reflector and glass window is about 4 so that maximum radiation falls on the glass window. This has helped in eliminating azimuthal tracking that is required in simple hot box solar cooker towards the Sun every hour because the width to length ratio of reflector is 1. It has been found that stagnation temperatures were 118.5oC and 108oC in large size non-tracking solar cooker and hot box solar cooker respectively. It takes about 2 h for soft food and 3 h for hard food. The cooker is capable of cooking 4.0 kg of food at a time. The efficiency of the large size non-tracking solar cooker has been found to be 27.5%. The cooker saves 5175 MJ of energy per year. The cost of the cooker is Rs. 10000.00 (1.0 US$ = Rs. 50.50. The payback period has been calculated by considering 10% annual interest, 5% maintenance cost and 5% inflation in fuel prices and maintenance cost. The payback period is least, i.e. 1.58 yr., with respect to electricity and maximum, i.e. 4.89 yr., with respect to kerosene. The payback periods are in increasing order with respect to fuel: electricity, coal, firewood, liquid petroleum gas, and kerosene. The shorter payback periods suggests that the use of large size non-tracking solar cooker is economical.

  14. Scrum of scrums solution for large size teams using scrum methodology

    OpenAIRE

    Qurashi, Saja Al; Qureshi, M. Rizwan Jameel

    2014-01-01

    Scrum is a structured framework to support complex product development. However, Scrum methodology faces a challenge of managing large teams. To address this challenge, in this paper we propose a solution called Scrum of Scrums. In Scrum of Scrums, we divide the Scrum team into teams of the right size, and then organize them hierarchically into a Scrum of Scrums. The main goals of the proposed solution are to optimize communication between teams in Scrum of Scrums; to make the system work aft...

  15. Medium and large sized mammals of a semideciduous forest remnant in southern Brazil

    OpenAIRE

    Pires, Daniel Paulo de Souza; Cademartori, Cristina Vargas

    2012-01-01

    Knowledge about mammals of the Atlantic Forest is still lacking, especially because some places remain poorly studied or inventoried, which makes conservation initiatives difficult. We aimed to determine the species richness and composition of medium and large sized mammals in a semideciduous forest remnant, Morro do Coco, thus contributing information about the occurrence of mammalian fauna in the metropolitan region of Porto Alegre, southern Brazil. The methods consisted of interviews with ...

  16. Modern methods of production of large-sized multicomponent optical systems

    Science.gov (United States)

    Galyavov, Igor R.; Belousov, Sergey P.; Ignatov, Aleksandr N.; Ponin, Oleg V.; Sharov, Aleksandr A.; Domnin, Aleksandr V.

    2016-10-01

    The article describes the technology of production of large-sized multicomponent optical systems of different function. All stages of a production cycle are considered: assembly of separate units of optical components, including aspherical and off-axis mirrors; preliminary assembly and adjustment of all system; final adjustment of optical system. Modern computer-controlled methods of testings and adjustment of multicomponent optical systems, using the examples of production of such systems at JSC LZOS, are described.

  17. Scrum of scrums solution for large size teams using scrum methodology

    OpenAIRE

    Qurashi, Saja Al; Qureshi, M. Rizwan Jameel

    2014-01-01

    Scrum is a structured framework to support complex product development. However, Scrum methodology faces a challenge of managing large teams. To address this challenge, in this paper we propose a solution called Scrum of Scrums. In Scrum of Scrums, we divide the Scrum team into teams of the right size, and then organize them hierarchically into a Scrum of Scrums. The main goals of the proposed solution are to optimize communication between teams in Scrum of Scrums; to make the system work aft...

  18. Design optimization of large-size format edge-lit light guide units

    Science.gov (United States)

    Hastanin, J.; Lenaerts, C.; Fleury-Frenette, K.

    2016-04-01

    In this paper, we present an original method of dot pattern generation dedicated to large-size format light guide plate (LGP) design optimization, such as photo-bioreactors, the number of dots greatly exceeds the maximum allowable number of optical objects supported by most common ray-tracing software. In the proposed method, in order to simplify the computational problem, the original optical system is replaced by an equivalent one. Accordingly, an original dot pattern is splitted into multiple small sections, inside which the dot size variation is less than the ink dots printing typical resolution. Then, these sections are replaced by equivalent cells with continuous diffusing film. After that, we adjust the TIS (Total Integrated Scatter) two-dimensional distribution over the grid of equivalent cells, using an iterative optimization procedure. Finally, the obtained optimal TIS distribution is converted into the dot size distribution by applying an appropriate conversion rule. An original semi-empirical equation dedicated to rectangular large-size LGPs is proposed for the initial guess of TIS distribution. It allows significantly reduce the total time needed to dot pattern optimization.

  19. Analysis of impact of large commercial aircraft on a prestressed containment building

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Kyoungsoo, E-mail: kylee@pvamu.edu [Center for Energy and Environmental Sustainability, Prairie View A and M University, Prairie view, TX, 77446 (United States); Han, Sang Eul, E-mail: hsang@inha.ac.kr [Department of Architectural Engineering, School of Architecture, Inha University, 253 Yonghyundong Nam-gu, Incheon, 402-751 (Korea, Republic of); Hong, Jung-Wuk, E-mail: j.hong@kaist.ac.kr [Department of Civil and Environmental Engineering, KAIST, 373-1 Guseon-dong, Yuseong-gu, Daejeon, 305-701 (Korea, Republic of)

    2013-12-15

    Highlights: • Aircraft impact analyses are performed using the missile–target interaction method. • A large commercial B747 aircraft is considered with erosion effect. • The rigid wall impact test shows the validity of the developed aircraft model. • The parametric studies on the fictitious containment building are performed. • The plastic failure of the target is governed by the impulse of aircraft at the first momentum peak. - Abstract: In this paper, the results of nonlinear dynamic analyses of a concrete containment building under extreme loads are presented. The impact of a large commercial B747 airliner is investigated as the extreme load, and a rigid wall impact test is performed using commercial nonlinear finite element codes. The impact forces exerted by the aircraft are verified compared with the time-dependent impact force provided by OECD/NEA (2002), which was calculated based on the so-called Riera method. The rigid wall impact analysis shows that the finite element model of a B747 is appropriate for the purpose of the aircraft crash analysis exposed to the external hazard of “Beyond Design-Basis Events” defined by U.S. Nuclear Regulatory Commission. Finally, the applicability of this methodology is further studied and verified by conducting parametric studies on the critical infrastructures of nuclear power plant containment structures.

  20. Large-scale amplitude liquid sloshing in container under pitching excitation

    Institute of Scientific and Technical Information of China (English)

    YUE BaoZeng

    2008-01-01

    Large-scale amplitude liquid sloshing in container under pitching excitation is numerically studied in this paper. Firstly, the kinematics of the ALE description is introduced and the fluid dynamics equations are revised in the ALE form. Secondly, the boundary condition about free-surface tension is represented in the form of weak integration that can be computed by the differential geometry method derived in the present paper and the normal vector on free surface is calculated using accurate formulas presented in this paper. Then the numerical discretized equations of fractional step finite element method are developed by Galerkin weighted residual method. Furthermore, the numerical simulation of large-scale amplitude sloshing of the liquid both in rectangular container and cylindrical container is carried out. The computed time evolution of the wave height, and free surface profiles at different time are obtained. Comparisons among the present numerical results with other published numerical results and experimental data confirm the effectiveness and validity of the method developed in this paper.

  1. Comparison of Different Periodontal Healing of Critical Size Noncontained and Contained Intrabony Defects in Beagles

    Science.gov (United States)

    Zang, Sheng-Qi; Kang, Shuai; Hu, Xin; Wang, Meng; Wang, Xin-Wen; Zhou, Tao; Wang, Qin-Tao

    2017-01-01

    Background: Regenerative techniques help promote the formation of new attachment and bone filling in periodontal defects. However, the dimensions of intraosseous defects are a key determinant of periodontal regeneration outcomes. In this study, we evaluated the efficacy of use of anorganic bovine bone (ABB) graft in combination with collagen membrane (CM), to facilitate healing of noncontained (1-wall) and contained (3-wall) critical size periodontal defects. Methods: The study began on March 2013, and was completed on May 2014. One-wall (7 mm × 4 mm) and 3-wall (5 mm × 4 mm) intrabony periodontal defects were surgically created bilaterally in the mandibular third premolars and first molars in eight beagles. The defects were treated with ABB in combination with CM (ABB + CM group) or open flap debridement (OFD group). The animals were euthanized at 8-week postsurgery for histological analysis. Two independent Student's t-tests (1-wall [ABB + CM] vs. 1-wall [OFD] and 3-wall [ABB + CM] vs. 3-wall [OFD]) were used to assess between-group differences. Results: The mean new bone height in both 1- and 3-wall intrabony defects in the ABB + CM group was significantly greater than that in the OFD group (1-wall: 4.99 ± 0.70 mm vs. 3.01 ± 0.37 mm, P < 0.05; 3-wall: 3.11 ± 0.59 mm vs. 2.08 ± 0.24 mm, P < 0.05). The mean new cementum in 1-wall intrabony defects in the ABB + CM group was significantly greater than that in their counterparts in the OFD group (5.08 ± 0.68 mm vs. 1.16 ± 0.38 mm; P < 0.05). Likewise, only the 1-wall intrabony defect model showed a significant difference with respect to junctional epithelium between ABB + CM and OFD groups (0.67 ± 0.23 mm vs. 1.12 ± 0.28 mm, P < 0.05). Conclusions: One-wall intrabony defects treated with ABB and CM did not show less periodontal regeneration than that in 3-wall intrabony defect. The noncontained 1-wall intrabony defect might be a more discriminative defect model for further research into periodontal

  2. High-speed atomic force microscopy for large scan sizes using small cantilevers

    Science.gov (United States)

    Braunsmann, Christoph; Schäffer, Tilman E.

    2010-06-01

    We present a high-speed atomic force microscope that exhibits a number of practical advantages over previous designs. Its central component is a high-speed scanner with a maximum scan size of 23 µm × 23 µm and a conveniently large sample stage area (6.5 mm × 6.5 mm). In combination with small cantilevers, image rates of up to 46 images s - 1 in air and 13 images s - 1 in liquid are reached under z-feedback control. By large scan size imaging of collagen fibrils in air, sample velocities of 8.8 mm s - 1 in the xy-direction and 11 mm s - 1 in the z-direction are reached. To provide optimized imaging conditions for both large and small scan sizes, a modular scanner design allows easily exchanging the x- and y-piezos. The scanner is therefore also suited for investigations on the molecular and atomic scale, which is demonstrated by imaging the step dynamics of a calcite surface during dissolution and the hexagonal lattice of a mica surface in liquid.

  3. The scaling relationship between telescope cost and aperture size for very large telescopes

    Science.gov (United States)

    van Belle, Gerard T.; Meinel, Aden Baker; Meinel, Marjorie Pettit

    2004-01-01

    Cost data for ground-based telescopes of the last century are analyzed for trends in the relationship between aperture size and cost. We find that for apertures built prior to 1980, costs scaled as aperture size to the 2.8 power, which is consistent with the precious finding of Meinel (1978). After 1980, 'traditional' monolithic mirror telescope costs have scaled as aperture to the 2.5 power. The large multiple mirror telescopes built or in construction during this time period (Keck, LBT, GTC) appear to deviate from this relationship with significant cost savings as a result, although it is unclear what power law such structures follow. We discuss the implications of the current cost-aperture size data on the proposed large telescope projects of the next ten to twenty years. Structures that naturally tend towards the 2.0 power in the cost-aperture relationship will be the favorable choice for future extremely large apertures; out expectation is that space-based structures will ultimately gain economic advantage over ground-based ones.

  4. Paleogenomic data suggest mammal-like genome size in the ancestral amniote and derived large genome size in amphibians.

    Science.gov (United States)

    Organ, C L; Canoville, A; Reisz, R R; Laurin, M

    2011-02-01

    An unsolved question in evolutionary genomics is whether amniote genomes have been expanding or contracting since the common ancestor of this diverse group. Here, we report on the polarity of amniote genome size evolution using genome size estimates for 14 extinct tetrapod genera from the Paleozoic and early Mesozoic Eras using osteocyte lacunae size as a correlate. We find substantial support for a phylogenetically controlled regression model relating genome size to osteocyte lacunae size (P of slopes amphibians, contractions along the diapsid lineage, and no directional change within the synapsid lineage leading to mammals.

  5. Differential behavior of plasmids containing chromosomal DNA insertions of various sizes during transformation and conjugation in Haemophilus influenzae

    Energy Technology Data Exchange (ETDEWEB)

    Balganesh, M.; Setlow, J.K.

    1985-01-01

    Plasmids with chromosomal insertions were constructed by removal of a 1.1-kilobase-pair piece from the 9.8-kilobase-pair vector plasmid pDM2 by EcoRI digestion and inserting in its place various lengths of chromosomal DNA (1.7, 3.4, and 9.0 kilobase pairs) coding for resistance to novobiocin. A fourth plasmid was constructed by insertion of the largest piece of chromosomal DNA into the SmaI site of pDM2. The plasmids without inserts were taken up poorly by competent cells and thus were considered not to contain specific DNA uptake sites. The presence of even the smallest insert of chromosomal DNA caused a large increase in transformation of Rec/sup +/ and Rec/sup -/ strains. The frequency of plasmid establishment in Rec/sup +/ cells by transformation increased exponentially with increasing insert size, but in Rec/sup -/ cells there was less transformation by the larger plasmids. Conjugal transfer of these plasmids was carried out with the 35-kilobase-pair mobilizing plasmid pHD147. The frequency of establishment of plasmids by this method not only was not markedly affected by the presence of the insertions, but also decreased somewhat with increase in insert size and was independent of rec-1 and rec-2 genes. Recombination between plasmid and chromosome was readily detected after transformation, but could not be detected after transconjugation even when the recipient cells were Rec/sup +/ and made competent. These data suggested that there is a special processing of plasmid DNA that enters the competent cells in transformation that makes possible recombination of homologous regions of the plasmid with the chromosome and pairing with the chromosome that aids plasmid establishment.

  6. A simple method for estimating genetic diversity in large populations from finite sample sizes

    Directory of Open Access Journals (Sweden)

    Rajora Om P

    2009-12-01

    Full Text Available Abstract Background Sample size is one of the critical factors affecting the accuracy of the estimation of population genetic diversity parameters. Small sample sizes often lead to significant errors in determining the allelic richness, which is one of the most important and commonly used estimators of genetic diversity in populations. Correct estimation of allelic richness in natural populations is challenging since they often do not conform to model assumptions. Here, we introduce a simple and robust approach to estimate the genetic diversity in large natural populations based on the empirical data for finite sample sizes. Results We developed a non-linear regression model to infer genetic diversity estimates in large natural populations from finite sample sizes. The allelic richness values predicted by our model were in good agreement with those observed in the simulated data sets and the true allelic richness observed in the source populations. The model has been validated using simulated population genetic data sets with different evolutionary scenarios implied in the simulated populations, as well as large microsatellite and allozyme experimental data sets for four conifer species with contrasting patterns of inherent genetic diversity and mating systems. Our model was a better predictor for allelic richness in natural populations than the widely-used Ewens sampling formula, coalescent approach, and rarefaction algorithm. Conclusions Our regression model was capable of accurately estimating allelic richness in natural populations regardless of the species and marker system. This regression modeling approach is free from assumptions and can be widely used for population genetic and conservation applications.

  7. Successful flexible bronchoscopic management of a large-sized aspirated partial denture.

    Science.gov (United States)

    Jamshed, Nayer; Madan, Karan; Ekka, Meera; Guleria, Randeep

    2014-03-20

    A 48-year-old male patient presented to the emergency room with a history of chest pain and breathlessness. Chest X-ray demonstrated a large radio-opaque foreign body in relation to the proximal right bronchial tree. The patient subsequently revealed a history of a misplaced denture 4 months previously. Urgent flexible bronchoscopy (FB) examination demonstrated a large partial denture impacted in the right intermediate bronchus, which was removed successfully using a flexible bronchoscope. Although rigid bronchoscopy (RB) is the procedure of choice for large-sized and impacted airway foreign bodies, the present case highlights the utility of FB in airway foreign body removal. In clinically stable patients with foreign body inhalation, FB can be employed initially as it is an outpatient and cost-effective procedure which can obviate the need for administration of general anaesthesia.

  8. Development of Detonation Flame Sprayed Cu-Base Coatings Containing Large Ceramic Particles

    Science.gov (United States)

    Tillmann, Wolfgang; Vogli, Evelina; Nebel, Jan

    2007-12-01

    Metal-matrix composites (MMCs) containing large ceramic particles as superabrasives are typically used for grinding stone, minerals, and concrete. Sintering and brazing are the key manufacturing technologies for grinding tool production. However, restricted geometry flexibility and the absence of repair possibilities for damaged tool surfaces, as well as difficulties of controlling material interfaces, are the main weaknesses of these production processes. Thermal spraying offers the possibility to avoid these restrictions. The research for this paper investigated a fabrication method based on the use of detonation flame spraying technology to bond large superabrasive particles (150-600 μm, needed for grinding minerals and stones) in a metallic matrix. Layer morphology and bonding quality are evaluated with respect to superabrasive material, geometry, spraying, and powder-injection parameters. The influence of process temperature and the possibilities of thermal treatment of MMC layers are analyzed.

  9. Effect of Large Finite-Size Wind Farms and Their Wakes on Atmospheric Boundary Layer Dynamics

    Science.gov (United States)

    Wu, Ka Ling; Porté-Agel, Fernando

    2016-04-01

    Through the use of large-eddy simulation, the effect of large finite-size wind farms and their wakes on conventionally-neutral atmospheric boundary layer (ABL) dynamics and power extraction is investigated. Specifically, this study focuses on a wind farm that comprises 25 rows of wind turbines, spanning a distance of 10 km. It is shown that large wind farms have a significant effect on internal boundary layer growth both inside and downwind of the wind farms. If the wind farm is large enough, the internal boundary layer interacts with the thermally-stratified free atmosphere above, leading to a modification of the ABL height and power extraction. In addition, it is shown that large wind farms create extensive wakes, which could have an effect on potential downwind wind farms. Specifically, for the case considered here, a power deficit as large as 8% is found at a distance of 10 km downwind from the wind farm. Furthermore, this study compares the wind farm wake dynamics for cases in which the conventionally neutral ABLs are driven by a unidirectional pressure gradient and Coriolis forces.

  10. Hydro-structural issues in the design of ultra large container ships

    Directory of Open Access Journals (Sweden)

    Sime Malenica

    2014-12-01

    Full Text Available The structural design of the ships includes two main issues which should be checked carefully, namely the extreme structural response (yielding & buckling and the fatigue structural response. Even if the corresponding failure modes are fundamentally different, the overall methodologies for their evaluation have many common points. Both issues require application of two main steps: deterministic calculations of hydro-structure interactions for given operating conditions on one side and the statistical post-processing in order to take into account the lifetime operational profile, on the other side. In the case of ultra large ships such as the container ships and in addition to the classical quasi-static type of structural responses the hydroelastic structural response becomes important. This is due to several reasons among which the following are the most important: the increase of the flexibility due to their large dimensions (Lpp close to 400 m which leads to the lower structural natural frequencies, very large operational speed (20 knots and large bow flare (increased slamming loads. The correct modeling of the hydroelastic ship structural response, and its inclusion into the overall design procedure, is significantly more complex than the evaluation of the quasi static structural response. The present paper gives an overview of the different tools and methods which are used in nowadays practice.

  11. Estimating the Size of a Large Network and its Communities from a Random Sample

    CERN Document Server

    Chen, Lin; Crawford, Forrest W

    2016-01-01

    Most real-world networks are too large to be measured or studied directly and there is substantial interest in estimating global network properties from smaller sub-samples. One of the most important global properties is the number of vertices/nodes in the network. Estimating the number of vertices in a large network is a major challenge in computer science, epidemiology, demography, and intelligence analysis. In this paper we consider a population random graph G = (V;E) from the stochastic block model (SBM) with K communities/blocks. A sample is obtained by randomly choosing a subset W and letting G(W) be the induced subgraph in G of the vertices in W. In addition to G(W), we observe the total degree of each sampled vertex and its block membership. Given this partial information, we propose an efficient PopULation Size Estimation algorithm, called PULSE, that correctly estimates the size of the whole population as well as the size of each community. To support our theoretical analysis, we perform an exhausti...

  12. Study on Properties of Environment-friendly Concrete Containing Large Amount of Industrial by-products

    Science.gov (United States)

    Fujiwara, H.; Maruoka, M.; Sadayama, C.; Nemoto, M.; Yoshikawa, K.; Yamaji, M.

    2015-11-01

    This study aims to reduce CO2 discharged from the cement and concrete industries by effective use of industrial by-products, such as fly ash, blast furnace slag, and so on. In this paper, the properties of concrete containing large amount of industrial by-products and very small amount of alkaline activator including cement or sludge from ready mixed concrete plant are analyzed. As the result, it was confirmed that concretes containing large amount of industrial by-products can achieve sufficient compressive strength. However, these concretes showed poor frost resistance. It was thought that the reason was coarsening of air void system and this caused their poor frost resistance. Therefore, in order to micronize the air void system and improve frost resistance, the combination of air entraining agent and antifoaming agent was applied. By this method, it was confirmed that the frost resistance of some these concrete improved. In this study, other properties of these concretes, such as fresh properties and other durability were evaluated and it was confirmed that these concretes show sufficient properties.

  13. Presence of nano-sized silica during in vitro digestion of foods containing silica as a food additive.

    NARCIS (Netherlands)

    Peters, R.; Kramer, E.; Oomen, A.G.; Rivera, Z.E.; Oegema, G.; Tromp, P.C.; Fokkink, R.; Rietveld, A.; Marvin, H.J.; Weigel, S.; Peijnenburg, A.A.; Bouwmeester, H.

    2012-01-01

    The presence, dissolution, agglomeration state, and release of materials in the nano-size range from food containing engineered nanoparticles during human digestion is a key question for the safety assessment of these materials. We used an in vitro model to mimic the human digestion. Food products s

  14. Presence of Nano-Sized Silica during In Vitro Digestion of Foods Containing Silica as a Food Additive

    NARCIS (Netherlands)

    Peters, R.J.B.; Kramer, E.H.M.; Oomen, A.G.; Rivera, Z.H.; Oegema, G.; Tromp, P.C.; Fokkink, R.G.; Rietveld, A.; Marvin, H.J.P.; Weigel, S.; Peijnenburg, A.A.C.M.; Bouwmeester, H.

    2012-01-01

    The presence, dissolution, agglomeration state, and release of materials in the nano-size range from food containing engineered nanoparticles during human digestion is a key question for the safety assessment of these materials. We used an in vitro model to mimic the human digestion. Food products s

  15. Presence of nano-sized silica during in vitro digestion of foods containing silica as a food additive

    NARCIS (Netherlands)

    Peters, R.; Kramer, E.; Oomen, A.G.; Herrera Rivera, Z.E.; Oegema, G.; Tromp, P.C.; Fokkink, R.; Rietveld, A.; Marvin, H.J.P.; Weigel, S.; Peijnenburg, A.A.C.M.; Bouwmeester, H.

    2012-01-01

    The presence, dissolution, agglomeration state, and release of materials in the nano-size range from food containing engineered nanoparticles during human digestion is a key question for the safety assessment of these materials. We used an in vitro model to mimic the human digestion. Food products s

  16. Phase Behavior and Domain Size in Sphingomyelin-Containing Lipid Bilayers

    Energy Technology Data Exchange (ETDEWEB)

    Petruzielo, Robin S [Cornell University; Heberle, Frederick A [ORNL; Drazba, Paul [ORNL; Katsaras, John [ORNL; Feigenson, Gerald [Cornell University

    2013-01-01

    Membrane raft size measurements are crucial to understanding the stability and functionality of rafts in cells. The challenge of accurately measuring raft size is evidenced by the disparate reports of domain sizes, which range from nanometers to microns for the ternary model membrane system sphingomyelin (SM)/1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC)/cholesterol (Chol). Using F rster resonance energy transfer (FRET) and differential scanning calorimetry (DSC), we established phase diagrams for porcine brain SM (bSM)/dioleoyl-sn-glycero-3-phosphocholine (DOPC)/Chol and bSM/POPC/Chol at 15 and 25 C. By combining two techniqueswith different spatial sensitivities, namely FRET and small-angle neutron scattering (SANS),we have significantly narrowed the uncertainty in domain size estimates for bSM/POPC/Chol mixtures. Compositional trends in FRET data revealed coexisting domains at 15 and 25 C for bothmixtures, while SANS measurements detected no domain formation for bSM/POPC/Chol. Together these results indicate that liquid domains in bSM/POPC/Chol are between 2 and 7 nmin radius at 25 C: that is, domains must be on the order of the 2 6 nmF rster distance of the FRET probes, but smaller than the ~7 nm minimum cluster size detectable with SANS. However, for palmitoyl SM (PSM)/POPC/Chol at a similar composition, SANS detected coexisting liquid domains. This increase in domain size upon replacing the natural SMcomponent (which consists of amixture of chain lengths) with synthetic PSM, suggests a role for SM chain length in modulating raft size in vivo.

  17. Characterizing the Large (cm-size) Grains Around Comet 103P/Hartley 2

    Science.gov (United States)

    Sunshine, Jessica M.; Feaga, Lori M.; Farnham, Tony; Protopapa, Silvia; Kelley, Michael S.; Engle, Anna

    2016-10-01

    During the flyby of comet 103P/Hartley 2, two populations of bright grains were identified in the coma. Small, 1 µm-sized, water ice-rich grains were observed near the small end of the nucleus that were dragged from the interior by CO2 gas emissions. At closest approach a population of larger grains was clearly seen in visible images off the large lobe. The estimated brightness of the isolated grains suggests that they are likely cm-sized particles and likely water ice-rich. Both sets of grains were simultaneously observed in visible images, at two different resolutions, and by Deep Impact infrared spectrometer. However, because of the difficulty in finding isolated grains in the infrared slit, the population of larger grains has not previously been characterized. Doing so allows us to determine both the reflected and thermal properties of the grains, which when compared to visible images can be used to constrain the size of the grains. Their spectral properties can also be used to definitively detect water ice as has been assumed from visible albedos. In addition, the infrared spectra can be used estimate the relative abundance and particle sizes of ice and non-ice components. The velocity and dynamics of these larger grains can also be characterized. These data will be compared with those of the population of smaller grains emanated directly from the nucleus.Funding from NASA'S Discovery Data Analysis Program (NNX16AJ93G) is greatfully acknowledged.

  18. Density functional calculations of large systems containing heavy elements by means of the regionalization algorithm

    Institute of Scientific and Technical Information of China (English)

    HU Xiangqian; LI Lemin

    2004-01-01

    The regionalized computational method is extended to the non-relativistic, scalar and 2-component relativistic density functional calculation of large systems containing transition series or heavy main-group metal elements. A large system is divided into several regions which can be considered as relatively independent quantum mechanical subsystems. Taking into account the Coulomb and exchange-correlation potentials as well as the Pauli repulsion exerted by the other subsystems, the Kohn-Sham equation related to subsystem K can be written as: (FK+FKP)CK =SKCKεK K=A,B,C,…,where FK,CK,SK,εK are the Fock matrix, the matrix of combination coefficients of orbitals, the overlap matrix of basis sets and the energy eigenvalue matrix, respectively. The matrix FKP reflects the Pauli repulsion from the other subsystems.FK may be non-relativistic, scalar or 2-component relativistic Fock matrix determined by the theoretical method related to the density functional calculations. The other matrices are mated with FK. Solving the Kohn-Sham equation for every subsystem and combining the results from the subsystem calculations, the electronic structural information of the whole system is derived. The density functional calculation of several molecules containing transition metal Ni or heavy main-group metal Tl or Bi is performed by the afore-mentioned regionalization algorithm. The obtained results for each molecule are compared with those from the density functional calculation of that molecule in its entirety in order to check the feasibility of the regionalization algorithm. It is found that with sufficiently large regional basis set in the subsystem calculation the accuracy of the results calculated by the regionalization algorithm is essentially the same as that from the calculation of the molecule in its entirety. With proper smaller regional basis sets the accuracy of the results calculated with the regionalization algorithm can still match the actual accuracy of the

  19. Effect of drop size on the impact thermodynamics for supercooled large droplet in aircraft icing

    Science.gov (United States)

    Zhang, Chen; Liu, Hong

    2016-06-01

    Supercooled large droplet (SLD), which can cause abnormal icing, is a well-known issue in aerospace engineering. Although efforts have been exerted to understand large droplet impact dynamics and the supercooled feature in the film/substrate interface, respectively, the thermodynamic effect during the SLD impact process has not received sufficient attention. This work conducts experimental studies to determine the effects of drop size on the thermodynamics for supercooled large droplet impingement. Through phenomenological reproduction, the rapid-freezing characteristics are observed in diameters of 400, 800, and 1300 μm. The experimental analysis provides information on the maximum spreading rate and the shrinkage rate of the drop, the supercooled diffusive rate, and the freezing time. A physical explanation of this unsteady heat transfer process is proposed theoretically, which indicates that the drop size is a critical factor influencing the supercooled heat exchange and effective heat transfer duration between the film/substrate interface. On the basis of the present experimental data and theoretical analysis, an impinging heating model is developed and applied to typical SLD cases. The model behaves as anticipated, which underlines the wide applicability to SLD icing problems in related fields.

  20. Modeling and simulation of 3D thermal stresses of large-sized castings in solidification processes

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    When heavy machines and large scaled receiver system of communication equipment are manufactured, it always needs to produce large- sized steel castings, aluminum castings and etc. Some defects of hot cracking by thermal stress often appear during solidification process as these castings are produced, which results in failure of castings.Therefore predicting the effects of technological parameters for production of castings on the thermal stress during solidification process becomes an important means. In this paper, the mathematical models have been established and numerical calculation of temperature fields by using finite difference method (FDM) and then thermal stress fields by using finite element method (FEM) during solidification process of castings have been carried out. The technological parameters of production have been optimized by the results of calculation and the defects of hot cracking have been eliminated. Modeling and simulation of 3D thermal stress during solidification processes of large-sized castings provided a scientific basis, which promoted further development of advanced manufacturing technique.

  1. Effect of Temperature and Ram Speed on Isothermal Extrusion for Large-size Tube with Piece-wing

    Institute of Scientific and Technical Information of China (English)

    He YANG; Jun ZHANG; Yangmin HE; Bingtao HAN

    2005-01-01

    Heat energy change during the extrusion of 7075 aluminium alloy large-size tube with piece-wing in a container was analyzed. Extrusion load vs ram displacement diagrams and exit temperature vs ram displacement diagrams at various speeds were obtained by 3D FEM simulation. Results show that the exit temperature becomes higher as the ram speed and displacement increase. For large-size tube with piece-wing, there is certainly a curve of ram speed decreasing with increasing ram displacement, which enables isothermal extrusion to be achieved. Therefore,an attempt was made to divide the working stroke into five different zones. Each of them has a preset speed that decreases from the ram displacement beginning to the ending. And then, new exit temperature vs ram displacement diagram was obtained by 3D FEM simulation for the five different speeds. It is shown that the variation of exit temperature is very small. Through the above research, a basic method for realizing isothermal extrusion of 7075large-size tube with piece-wing was obtained, that is, the working stroke was divided into several different zones with a decreasing speed during extrusion, each zones' speed was real-time adjusted on the feedback signal of exit temperature by proportional hydraulic valve through closed-loop control. The engineering experiment verification was carried out on 100 MN aluminium extrusion press with oil-driven double action. The experimental results of the exit temperature agrees with the simulation ones. The achievements of this study may serve as a significant guide to the practice of the relevant processes, particularly for isothermal extrusion. The verified method has been used in the design and manufacture of 125 MN aluminium extrusion press with oil-driven double action.

  2. HOW THE ROCKY FLATS ENVIRONMENTAL TECHNOLOGY SITE DEVELOPED A NEW WASTE PACKAGE USING A POLYUREA COATING THAT IS SAFELY AND ECONOMICALLY ELIMINATING SIZE REDUCTION OF LARGE ITEMS

    Energy Technology Data Exchange (ETDEWEB)

    Dorr, Kent A.; Hogue, Richard S.; Kimokeo, Margaret K.

    2003-02-27

    One of the major challenges involved in closing the Rocky Flats Environmental Technology Site (RFETS) is the disposal of extremely large pieces of contaminated production equipment and building debris. Past practice has been to size reduce the equipment into pieces small enough to fit into approved, standard waste containers. Size reducing this equipment is extremely expensive, and exposes workers to high-risk tasks, including significant industrial, chemical, and radiological hazards. RFETS has developed a waste package using a Polyurea coating for shipping large contaminated objects. The cost and schedule savings have been significant.

  3. Biophysical interactions control the size and abundance of large phytoplankton chains at the Ushant tidal front.

    Directory of Open Access Journals (Sweden)

    José M Landeira

    Full Text Available Phytoplankton blooms are usually dominated by chain-forming diatom species that can alter food pathways from primary producers to predators by reducing the interactions between intermediate trophic levels. The food-web modifications are determined by the length of the chains; however, the estimation is biased because traditional sampling strategies damage the chains and, therefore, change the phytoplankton size structure. Sedimentological studies around oceanic fronts have shown high concentrations of giant diatom mats (>1 cm in length, suggesting that the size of diatom chains is underestimated in the pelagic realm. Here, we investigate the variability in size and abundance of phytoplankton chains at the Ushant tidal front (NW France using the Video Fluorescence Analyzer (VFA, a novel and non-invasive system. CTD and Scanfish profiling characterized a strong temperature and chlorophyll front, separating mixed coastal waters from the oceanic-stratified domain. In order to elucidate spring-neap variations in the front, vertical microstructure profiler was used to estimate the turbulence and vertical nitrate flux. Key findings were: (1 the VFA system recorded large diatom chains up to 10.7 mm in length; (2 chains were mainly distributed in the frontal region, with maximum values above the pycnocline in coincidence with the maximum chlorophyll; (3 the diapycnal fluxes of nitrate enabled the maintenance of the bloom in the frontal area throughout the spring-neap tidal cycle; (4 from spring to neap tide the chains length was significantly reduced; (5 during neap tide, the less intense vertical diffusion of nutrients, as well as the lower turbulence around the chains, intensified nutrient-depleted conditions and, thus, very large chains became disadvantageous. To explain this pattern, we suggest that size plasticity is an important ecological trait driving phytoplankton species competition. Although this plasticity behavior is well known from

  4. RESOURCE SAVING TECHNOLOGICAL PROCESS OF LARGE-SIZE DIE THERMAL TREATMENT

    Directory of Open Access Journals (Sweden)

    L. A. Glazkov

    2009-01-01

    Full Text Available The given paper presents a development of a technological process pertaining to hardening large-size parts made of die steel. The proposed process applies a water-air mixture instead of a conventional hardening medium that is industrial oil.While developing this new technological process it has been necessary to solve the following problems: reduction of thermal treatment duration, reduction of power resource expense (natural gas and mineral oil, elimination of fire danger and increase of process ecological efficiency. 

  5. Development of Large-size Ultrasonic Sonotrodes for Cavitation Treatment of Molten Metals

    Science.gov (United States)

    Komarov, Sergey; Ishiwata, Yasuo

    This work presents results of the development of large-size high-amplitude ceramic sonotrodes destined for use in cavitation treatment of molten metals. The sonotrodes were characterized for their vibration amplitude, erosion resistance and cavitation-producing ability in aluminum melts. The ability of the sonotrodes to refine the grain structure was examined by applying them to the DC casting of Al-Si hypereutectic alloys. The results showed that the sonotrodes have excellent performance characteristics, and they possess far superior erosion resistance and endurance than those made of such high-resistance refractory metals as Nb alloys.

  6. Verification measurements of the IRMM-1027 and the IAEA large-sized dried (LSD) spikes.

    Science.gov (United States)

    Jakopič, R; Aregbe, Y; Richter, S; Zuleger, E; Mialle, S; Balsley, S D; Repinc, U; Hiess, J

    2017-01-01

    In the frame of the accountancy measurements of the fissile materials, reliable determinations of the plutonium and uranium content in spent nuclear fuel are required to comply with international safeguards agreements. Large-sized dried (LSD) spikes of enriched (235)U and (239)Pu for isotope dilution mass spectrometry (IDMS) analysis are routinely applied in reprocessing plants for this purpose. A correct characterisation of these elements is a pre-requirement for achieving high accuracy in IDMS analyses. This paper will present the results of external verification measurements of such LSD spikes performed by the European Commission and the International Atomic Energy Agency.

  7. 7 CFR 987.112a - Grade, size, and container requirements for each outlet category.

    Science.gov (United States)

    2010-01-01

    ... (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts... shall be increased to 15 percent. These size requirements are in addition to, and do not supersede, the..., trays, or other like stiffening material: Provided, That DAC dates shipped for sale in Canada in plastic...

  8. Accelerating inference for diffusions observed with measurement error and large sample sizes using approximate Bayesian computation

    DEFF Research Database (Denmark)

    Picchini, Umberto; Forman, Julie Lyng

    2016-01-01

    In recent years, dynamical modelling has been provided with a range of breakthrough methods to perform exact Bayesian inference. However, it is often computationally unfeasible to apply exact statistical methodologies in the context of large data sets and complex models. This paper considers...... a nonlinear stochastic differential equation model observed with correlated measurement errors and an application to protein folding modelling. An approximate Bayesian computation (ABC)-MCMC algorithm is suggested to allow inference for model parameters within reasonable time constraints. The ABC algorithm...... applications. A simulation study is conducted to compare our strategy with exact Bayesian inference, the latter resulting two orders of magnitude slower than ABC-MCMC for the considered set-up. Finally, the ABC algorithm is applied to a large size protein data. The suggested methodology is fairly general...

  9. Temperature Uniformity of Wafer on a Large-Sized Susceptor for a Nitride Vertical MOCVD Reactor

    Institute of Scientific and Technical Information of China (English)

    LI Zhi-Ming; JIANG Hai-Ying; HAN Yan-Bin; LI Jin-Ping; YIN Jian-Qin; ZHANG Jin-Cheng

    2012-01-01

    The effect of coil location on wafer temperature is analyzed in a vertical MOCVD reactor by induction heating.It is observed that the temperature distribution in the wafer with the coils under the graphite susceptor is more uniform than that with the coils around the outside wall of the reactor.For the case of coils under the susceptor,we find that the thickness of the susceptor,the distance from the coils to the susceptor bottom and the coil turns significantly affect the temperature uniformity of the wafer. An optimization process is executed for a 3-inch susceptor with this kind of structure,resulting in a large improvement in the temperature uniformity.A further optimization demonstrates that the new susceptor structure is also suitable for either multiple wafers or large-sized wafers approaching 6 and 8 inches.

  10. Dislocation Analysis for Large-sized Sapphire Single Crystal Grown by SAPMAC Method

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    In this paper, large-sized sapphire (Φ230×210 mm, 27.5 kg) was grown by SAPMAC method (sapphire growth technique with micro-pulling and shoulder-expanding at the cooled center). Dislocation peculiarity in large sapphire boule (0001) basal plane was investigated by chemical etching, scanning electron microscopy and X-ray topography method. The triangular dislocation etch pit measured is 7.6×101~8.0×102 cm-2, in which relative high-density dislocations were generated at both initial and final stages of crystal growth. The analysis of single-crystal X-ray topography shows that there are no apparent sub-grain boundaries; the dislocation lines are isolated and straight. Finally, the origins of low-density dislocation in sapphire crystal are discussed by numerical analysis method.

  11. Reliability design of mono-leaf spring for front-axle suspension of large-sized trucks

    Energy Technology Data Exchange (ETDEWEB)

    Savaidis, G. [Aristotle Univ. of Thessaloniki, Dept. of Mechanical Engineering (Greece); Schwaiger, F. [MAN Nutzfahrzeuge AG, Munich (Germany); Momiyama, F.; Yamazumi, T.; Muramatsu, K. [Horikiri Inc., Chiba-Pref. (Japan)

    2004-07-01

    This paper deals with the development of a fatigue-accurate suspension system for large-sized trucks based on mono-leaf steel springs, It shows the fulfillment of the demands for lightweight construction, sufficient fatigue life and fail-safe behaviour. The paper contains the fatigue load assumptions used for the non-linear finite-element stress-strain analysis, the experimental verification by means of measured load, stress and strain data determined by driving quasi-static manoeuvres and over various rough road segments with a prototype vehicle, as well as the experimental uniaxial and multiaxial fatigue tests required for the durability approval. The fatigue lives achieved, confirm the adequate service life of the developed spring. In addition, appropriate vehicle tests on a test track with a custom-made mono-leaf spring system confirmed the fail-safe design of the suspension system. (orig.)

  12. Growth of large size lithium niobate single crystals of high quality by tilting-mirror-type floating zone method

    Energy Technology Data Exchange (ETDEWEB)

    Sarker, Abdur Razzaque, E-mail: razzaque_ru2000@yahoo.com [Department of Physics, University of Rajshahi (Bangladesh)

    2016-05-15

    Large size high quality LiNbO{sub 3} single crystals were grown successfully by tilting-mirror-type floating zone (TMFZ) technique. The grown crystals were characterized by X-ray diffraction, etch pits density measurement, Impedance analysis, Vibrating sample magnetometry (VSM) and UV-Visible spectrometry. The effect of mirror tilting during growth on the structural, electrical, optical properties and defect density of the LiNbO{sub 3} crystals were investigated. It was found that the defect density in the crystals reduced for tilting the mirror in the TMFZ method. The chemical analysis revealed that the grown crystals were of high quality with uniform composition. The single crystals grown by TMFZ method contains no low-angle grain boundaries, indicating that they can be used for high efficiency optoelectronic devices. (author)

  13. Mechanisms for exporting large-sized cargoes from the endoplasmic reticulum.

    Science.gov (United States)

    Saito, Kota; Katada, Toshiaki

    2015-10-01

    Cargo proteins exported from the endoplasmic reticulum to the Golgi apparatus are typically transported in coat protein complex II (COPII)-coated vesicles of 60-90 nm diameter. Several cargo molecules including collagens and chylomicrons form structures that are too large to be accommodated by these vesicles, but their secretion still requires COPII proteins. Here, we first review recent progress on large cargo secretions derived especially from animal models and human diseases, which indicate the importance of COPII proteins. We then discuss the recent isolation of specialized factors that modulate the process of COPII-dependent cargo formation to facilitate the exit of large-sized cargoes from the endoplasmic reticulum. Based on these findings, we propose a model that describes the importance of the GTPase cycle for secretion of oversized cargoes. Next, we summarize reports that describe the structures of COPII proteins and how these results provide insight into the mechanism of assembly of the large cargo carriers. Finally, we discuss what issues remain to be solved in the future.

  14. Extreme value prediction of the wave-induced vertical bending moment in large container ships

    DEFF Research Database (Denmark)

    Andersen, Ingrid Marie Vincent; Jensen, Jørgen Juncher

    2015-01-01

    in the present paper is based on time series of full scale measurements from three large container ships of 8600, 9400 and 14000 TEU. When carrying out the extreme value estimation the peak-over-threshold (POT) method combined with an appropriate extreme value distribution is applied. The choice of a proper...... increase the extreme hull girder response significantly. Focus in the present paper is on the influence of the hull girder flexibility on the extreme response amidships, namely the wave-induced vertical bending moment (VBM) in hogging, and the prediction of the extreme value of the same. The analysis...... threshold level as well as the statistical correlation between clustered peaks influence the extreme value prediction and are taken into consideration in the present paper....

  15. Fracture of graphite/polymer composite tension panels containing large cracks

    Science.gov (United States)

    Avery, Susan S.; Chaudhuri, Jharna; Avery, John G.

    The static tensile fracture of graphite reinforced polymer laminates containing large through the thickness cracks was experimentally studied using 72 panels with mechanically applied through-center cracks from 2.54 to 10.16 cm. Two polymer systems under consideration were PEEK and 3501 epoxy. Results show that both the undamaged and damaged strength of panels with graphite/PEEK are greater than the strength of panels made with graphite/epoxy. The notch-sensitivities of the two materials were similar, and varied with layup configuration. A comparison of the experimental results with analytical predictions based on selected linear elastic fracture mechancis models showed a poor correlation. However, the Mar-Lin microfracture model provided a good correlation between predicted and measured residual strength, which confirmed the experimental finding that the residual strength varied approximately with the inverse fourth root of the crack length.

  16. Search for squarks and gluinos in events containing jets and a large imbalance in transverse energy

    Energy Technology Data Exchange (ETDEWEB)

    Abbott, B.; Abolins, M.; Abramov, V.; Acharya, B.S.; Adam, I.; Adams, D.L.; Adams, M.; Ahn, S.; Alves, G.A.; Amos, N.; Anderson, E.W.; Baarmand, M.M.; Babintsev, V.V.; Babukhadia, Levan R.; Baden, A.; Baldin, B.; Banerjee, S.; Bantly, J.; Barberis, E.; Baringer, P.; Bartlett, J.F.; /Buenos Aires U. /Rio de Janeiro, CBPF /Rio de Janeiro State U.

    1999-02-01

    Using data corresponding to an integrated luminosity of 79 pb{sup -1}, D0 has searched for events containing multiple jets and large missing transverse energy in p{bar p} collisions at {radical}s = 1.8 TeV at the Fermilab Tevatron collider. Observing no significant excess beyond what is expected from the standard model, they set limits on the masses of squarks and gluinos and on the model parameters m{sub 0} and m{sub 1/2}, in the framework of the minimal low-energy supergravity models of supersymmetry. For tan {beta} = 2 and A{sub 0} = 0, with {mu} < 0, they exclude all models with m{sub q} {approx} < 250 GeV/c{sup 2}. For models with equal squark and gluino masses, they exclude m < 260 GeV/c{sup 2}.

  17. Search for Squarks and Gluinos in Events Containing Jets and a Large Imbalance in Transverse Energy

    Energy Technology Data Exchange (ETDEWEB)

    Abbott, B. [New York University, New York, New York 10003 (United States); Abolins, M. [Michigan State University, East Lansing, Michigan 48824 (United States); Abramov, V. [Institute for High Energy Physics, Protvino, Russia (Russian Federation); Acharya, B. S. [Tata Institute of Fundamental Research, Mumbai, (India); Adam, I. [Columbia University, New York, New York 10027 (United States); Adams, D. L. [Rice University, Houston, Texas 77005 (United States); Adams, M. [University of Illinois at Chicago, Chicago, Illinois 60607 (United States); Ahn, S. [Fermi National Accelerator Laboratory, Batavia, Illinois 60510 (United States); Alves, G. A. [LAFEX, Centro Brasileiro de Pesquisas Fisicas, Rio de Janiero, (Brazil); Amos, N. [University of Michigan, Ann Arbor, Michigan 48109 (United States)] (and others)

    1999-12-13

    Using data corresponding to an integrated luminosity of 79 pb{sup -1} , D0 has searched for events containing multiple jets and large missing transverse energy in pp collisions at {radical}(s)=1.8 TeV at the Fermilab Tevatron collider. Observing no significant excess beyond what is expected from the standard model, we set limits on the masses of squarks and gluinos and on the model parameters m{sub 0} and m{sub 1/2} , in the framework of the minimal low-energy supergravity models of supersymmetry. For tan {beta}=2 and A{sub 0}=0 , with {mu}<0 , we exclude all models with m{sub q(tilde} {sub sign)}<250 GeV/c{sup 2} . For models with equal squark and gluino masses, we exclude m<260 GeV/c{sup 2} . (c) 1999 The American Physical Society.

  18. Search for Squarks and Gluinos in Events Containing Jets and a Large Imbalance in Transverse Energy

    Science.gov (United States)

    Abbott, B.; Abolins, M.; Abramov, V.; Acharya, B. S.; Adam, I.; Adams, D. L.; Adams, M.; Ahn, S.; Alves, G. A.; Amos, N.; Anderson, E. W.; Baarmand, M. M.; Babintsev, V. V.; Babukhadia, L.; Baden, A.; Baldin, B.; Banerjee, S.; Bantly, J.; Barberis, E.; Baringer, P.; Bartlett, J. F.; Belyaev, A.; Beri, S. B.; Bertram, I.; Bezzubov, V. A.; Bhat, P. C.; Bhatnagar, V.; Bhattacharjee, M.; Biswas, N.; Blazey, G.; Blessing, S.; Bloom, P.; Boehnlein, A.; Bojko, N. I.; Borcherding, F.; Boswell, C.; Brandt, A.; Breedon, R.; Briskin, G.; Brock, R.; Bross, A.; Buchholz, D.; Burtovoi, V. S.; Butler, J. M.; Carvalho, W.; Casey, D.; Casilum, Z.; Castilla-Valdez, H.; Chakraborty, D.; Chekulaev, S. V.; Chen, W.; Choi, S.; Chopra, S.; Choudhary, B. C.; Christenson, J. H.; Chung, M.; Claes, D.; Clark, A. R.; Cobau, W. G.; Cochran, J.; Coney, L.; Cooper, W. E.; Coppage, D.; Cretsinger, C.; Cullen-Vidal, D.; Cummings, M. A.; Cutts, D.; Dahl, O. I.; Davis, K.; de, K.; del Signore, K.; Demarteau, M.; Denisov, D.; Denisov, S. P.; Diehl, H. T.; Diesburg, M.; di Loreto, G.; Draper, P.; Ducros, Y.; Dudko, L. V.; Dugad, S. R.; Dyshkant, A.; Edmunds, D.; Ellison, J.; Elvira, V. D.; Engelmann, R.; Eno, S.; Eppley, G.; Ermolov, P.; Eroshin, O. V.; Evdokimov, V. N.; Fahland, T.; Fatyga, M. K.; Feher, S.; Fein, D.; Ferbel, T.; Fisk, H. E.; Fisyak, Y.; Flattum, E.; Forden, G. E.; Fortner, M.; Frame, K. C.; Fuess, S.; Gallas, E.; Galyaev, A. N.; Gartung, P.; Gavrilov, V.; Geld, T. L.; Genik, R. J.; Genser, K.; Gerber, C. E.; Gershtein, Y.; Gibbard, B.; Gobbi, B.; Gómez, B.; Gómez, G.; Goncharov, P. I.; González Solís, J. L.; Gordon, H.; Goss, L. T.; Gounder, K.; Goussiou, A.; Graf, N.; Grannis, P. D.; Green, D. R.; Greenlee, H.; Grinstein, S.; Grudberg, P.; Grünendahl, S.; Guglielmo, G.; Guida, J. A.; Guida, J. M.; Gupta, A.; Gurzhiev, S. N.; Gutierrez, G.; Gutierrez, P.; Hadley, N. J.; Haggerty, H.; Hagopian, S.; Hagopian, V.; Hahn, K. S.; Hall, R. E.; Hanlet, P.; Hansen, S.; Hauptman, J. M.; Hebert, C.; Hedin, D.; Heinson, A. P.; Heintz, U.; Hernández-Montoya, R.; Heuring, T.; Hirosky, R.; Hobbs, J. D.; Hoeneisen, B.; Hoftun, J. S.; Hsieh, F.; Hu, Tong; Ito, A. S.; Jaques, J.; Jerger, S. A.; Jesik, R.; Joffe-Minor, T.; Johns, K.; Johnson, M.; Jonckheere, A.; Jones, M.; Jöstlein, H.; Jun, S. Y.; Jung, C. K.; Kahn, S.; Kalbfleisch, G.; Karmanov, D.; Karmgard, D.; Kehoe, R.; Kim, S. K.; Klima, B.; Klopfenstein, C.; Ko, W.; Kohli, J. M.; Koltick, D.; Kostritskiy, A. V.; Kotcher, J.; Kotwal, A. V.; Kozelov, A. V.; Kozlovsky, E. A.; Krane, J.; Krishnaswamy, M. R.; Krzywdzinski, S.; Kuleshov, S.; Kulik, Y.; Kunori, S.; Landry, F.; Landsberg, G.; Lauer, B.; Leflat, A.; Li, J.; Li, Q. Z.; Lima, J. G.; Lincoln, D.; Linn, S. L.; Linnemann, J.; Lipton, R.; Lobkowicz, F.; Lucotte, A.; Lueking, L.; Lyon, A. L.; Maciel, A. K.; Madaras, R. J.; Madden, R.; Magaña-Mendoza, L.; Manankov, V.; Mani, S.; Mao, H. S.; Markeloff, R.; Marshall, T.; Martin, M. I.; Mauritz, K. M.; May, B.; Mayorov, A. A.; McCarthy, R.; McDonald, J.; McKibben, T.; McKinley, J.; McMahon, T.; Melanson, H. L.; Merkin, M.; Merritt, K. W.; Miao, C.; Miettinen, H.; Mincer, A.; Mishra, C. S.; Mokhov, N.; Mondal, N. K.; Montgomery, H. E.; Mooney, P.; Mostafa, M.; da Motta, H.; Murphy, C.; Nang, F.; Narain, M.; Narasimham, V. S.; Narayanan, A.; Neal, H. A.; Negret, J. P.; Nemethy, P.; Norman, D.; Oesch, L.; Oguri, V.; Oshima, N.; Owen, D.; Padley, P.; Para, A.; Parashar, N.; Park, Y. M.; Partridge, R.; Parua, N.; Paterno, M.; Pawlik, B.; Perkins, J.; Peters, M.; Piegaia, R.; Piekarz, H.; Pischalnikov, Y.; Pope, B. G.; Prosper, H. B.; Protopopescu, S.; Qian, J.; Quintas, P. Z.; Raja, R.; Rajagopalan, S.; Ramirez, O.; Reucroft, S.; Rijssenbeek, M.; Rockwell, T.; Roco, M.; Rubinov, P.; Ruchti, R.; Rutherfoord, J.; Sánchez-Hernández, A.; Santoro, A.; Sawyer, L.; Schamberger, R. D.; Schellman, H.; Sculli, J.; Shabalina, E.; Shaffer, C.; Shankar, H. C.; Shivpuri, R. K.; Shpakov, D.; Shupe, M.; Singh, H.; Singh, J. B.; Sirotenko, V.; Smith, E.; Smith, R. P.; Snihur, R.; Snow, G. R.; Snow, J.; Snyder, S.; Solomon, J.; Sosebee, M.; Sotnikova, N.; Souza, M.; Steinbrück, G.; Stephens, R. W.; Stevenson, M. L.; Stichelbaut, F.; Stoker, D.; Stolin, V.; Stoyanova, D. A.; Strauss, M.; Streets, K.; Strovink, M.; Sznajder, A.; Tamburello, P.; Tarazi, J.; Tartaglia, M.; Thomas, T. L.; Thompson, J.; Trippe, T. G.; Tuts, P. M.; Vaniev, V.; Varelas, N.; Varnes, E. W.; Volkov, A. A.; Vorobiev, A. P.; Wahl, H. D.; Wang, G.; Warchol, J.; Watts, G.; Wayne, M.; Weerts, H.; White, A.; White, J. T.; Wightman, J. A.; Willis, S.; Wimpenny, S. J.; Wirjawan, J. V.; Womersley, J.; Won, E.; Wood, D. R.; Wu, Z.; Yamada, R.; Yamin, P.; Yasuda, T.; Yepes, P.; Yip, K.; Yoshikawa, C.; Youssef, S.; Yu, J.; Yu, Y.; Zhang, B.

    1999-12-01

    Using data corresponding to an integrated luminosity of 79 pb-1, D0 has searched for events containing multiple jets and large missing transverse energy in pp¯ collisions at s = 1.8 TeV at the Fermilab Tevatron collider. Observing no significant excess beyond what is expected from the standard model, we set limits on the masses of squarks and gluinos and on the model parameters m0 and m1/2, in the framework of the minimal low-energy supergravity models of supersymmetry. For tanβ = 2 and A0 = 0, with μ<0, we exclude all models with mq~<250 GeV/c2. For models with equal squark and gluino masses, we exclude m<260 GeV/c2.

  19. Parallel algorithm of solidification process simulation for large-sized system of liquid metal atoms

    Institute of Scientific and Technical Information of China (English)

    董科军; 刘让苏; 郑采星; 刘海蓉; 彭平; 卢小勇; 胡庆丰; 何新芳

    2003-01-01

    A parallel arithmetic program for the molecular dynamics (MD) simulation study of a large-sized system consisting of 50 000-100 000 atoms of liquid metals is reformed, based on the cascade arithmetic program used for the molecular dynamics simulation study of a small-sized system consisting of 500-1 000 atoms. The program is used to simulate the rapid solidification processes of liquid metal Al system. Some new results, such as larger clusters composed of more than 3-6 smaller clusters (icosahedra or defect icosahedra) obtained in the system of 50 000 atoms, however, the larger clusters can not be seen in the small-sized system of 500-1 000 atoms. On the other hand, the results from this simulation study would be more closed to the real situation of the system under consideration because the influence of boundary conditions is decreased remarkably. It can be expected that from the parallel algorithm combined with the higher performance super-computer, the total number of atoms in simulation system can be enlarged again up to tens, even hundreds times in the near future.

  20. Effect of polymorphism in the leukemia inhibitory factor gene on litter size in Large White pigs.

    Science.gov (United States)

    Lin, H C; Liu, G F; Wang, A G; Kong, L J; Wang, X F; Fu, J L

    2009-09-01

    DNA polymorphism of the porcine leukemia inhibitory factory (LIF) was investigated and used to study the effects on litter size in Large White pigs. A total of 2,167 litter records from 420 sows genotyped at two SNP loci (LIF1 and LIF2) within LIF gene were analyzed to determine whether LIF influenced total number born (TNB) and number born alive (NBA). The results indicated that B allele at LIF1 locus and A allele at LIF2 locus seem to have advantageous effects on litter size. However, the combined analyzed results demonstrated that genotype AAAA, ABBB, and BBBB are better than genotype AAAB, AABB, and ABAB for TNB and NBA in either third to eighth parity or all parities. In all parities, the sows with AAAA genotype had an advantage of 1.76 piglets (P NBA per litter over the AAAB sows, respectively. The results in this study demonstrated that LIF gene was significantly associated with litter size in pigs.

  1. Flower size and longevity influence florivory in the large-flowered shrub Cistus ladanifer

    Science.gov (United States)

    Teixido, Alberto L.; Méndez, Marcos; Valladares, Fernando

    2011-09-01

    Plants with larger and longer-lived flowers receive more pollinator visits and increase reproductive success, though may also suffer more from antagonistic interactions with animals. Florivores can reduce fruit and seed production, so selection on flower size, floral longevity and/or number of flowers may thus be determined by the relative effects of both pollinators and florivores. In this study flowers of Cistus ladanifer, a large-flowered Mediterranean shrub, were monitored to evaluate the effects of flower size, floral longevity and number of flowers on levels of florivory in four populations. Number of flowers was variable but did not differ among populations. Both flower size and floral longevity of C. ladanifer showed broad variation and significantly differed among populations. Overall, 7% of flowers suffered attack by florivores, which were mainly ants picking the stamens and beetles consuming petals and pollen. Within-populations, larger and longer-lived flowers tended to be affected by florivores more frequently. The low overall incidence of florivores and its lack of between-population variation suggest that florivory may not influence intraspecific variation of these floral traits. However, moderate florivory levels on the largest and longest-lived flowers open the possibility of exerting selection towards smaller and shorter-lived flowers in some of the populations studied.

  2. Fragmentation and reliable size distributions of large ammonia and water clusters

    Science.gov (United States)

    Bobbert, C.; Schütte, S.; Steinbach, C.; Buck, U.

    2002-05-01

    The interaction of large ammonia and water clusters in the size range from < n rangle = 10 to 3 400 with electrons is investigated in a reflectron time-of-flight mass spectrometer. The clusters are generated in adiabatic expansions through conical nozzles and are nearly fragmentation free detected by single photon ionization after they have been doped by one sodium atom. For ammonia also the (1+1) resonance enhanced two photon ionization through the tilde A state with v=6 operates similarly. In this way reliable size distributions of the neutral clusters are obtained which are analyzed in terms of a modified scaling law of the Hagena type [Surf. Sci. 106, 101 (1981)]. In contrast, using electron impact ionization, the clusters are strongly fragmented when varying the electron energy between 150 and 1 500 eV. The number of evaporated molecules depends on the cluster size and the energy dependence follows that of the stopping power of the solid material. Therefore we attribute the operating mechanism to that which is also responsible for the electronic sputtering of solid matter. The yields, however, are orders of magnitude larger for clusters than for the solid. This result is a consequence of the finite dimensions of the clusters which cannot accommodate the released energy.

  3. Shift in a large river fish assemblage: body-size and trophic structure dynamics.

    Directory of Open Access Journals (Sweden)

    Kyle J Broadway

    Full Text Available As the intensity and speed of environmental change increase at both local and global scales it is imperative that we gain a better understanding of the ecological implications of community shifts. While there has been substantial progress toward understanding the drivers and subsequent responses of community change (e.g. lake trophic state, the ecological impacts of food web changes are far less understood. We analyzed Wabash River fish assemblage data collected from 1974-2008, to evaluate temporal variation in body-size structure and functional group composition. Two parameters derived from annual community size-spectra were our major response variables: (1 the regression slope is an index of ecological efficiency and predator-prey biomass ratios, and (2 spectral elevation (regression midpoint height is a proxy for food web capacity. We detected a large assemblage shift, over at least a seven year period, defined by dramatic changes in abundance (measured as catch-per-unit-effort of the dominant functional feeding groups among two time periods; from an assemblage dominated by planktivore-omnivores to benthic invertivores. There was a concurrent increase in ecological efficiency (slopes increased over time following the shift associated with an increase in large-bodied low trophic level fish. Food web capacity remained relatively stable with no clear temporal trends. Thus, increased ecological efficiency occurred simultaneous to a compensatory response that shifted biomass among functional feeding groups.

  4. Prototyping of Hexagonal Light Concentrators for the Large-Sized Telescopes of the Cherenkov Telescope Array

    CERN Document Server

    ,

    2015-01-01

    Reflective light concentrators with hexagonal entrance and exit apertures are frequently used at the focal plane of gamma-ray telescopes in order to reduce the size of the dead area caused by the geometries of the photodetectors, as well as to reduce the amount of stray light entering at large field angles. The focal plane of the large-sized telescopes (LSTs) of the Cherenkov Telescope Array (CTA) will also be covered by hexagonal light concentrators with an entrance diameter of 50 mm (side to side) to maximize the active area and the photon collection efficiency, enabling realization of a very low energy threshold of 20 GeV. We have developed a prototype of this LST light concentrator with an injection-molded plastic cone and a specular multilayer film. The shape of the plastic cone has been optimized with a cubic B\\'{e}zier curve and a ray-tracing simulation. We have also developed a multilayer film with very high reflectance ($\\gtrsim95$\\%) along wide wavelength and angle coverage. The current status of th...

  5. Thermal Stresses and Cracks During the Growth of Large-sized Sapphire with SAPMAC Method

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The finite-element method has been used to study the thermal stress distribution in large-sized sapphire crystals grown with the sapphire growth technique with micro-pulling and shoulder-expanding at cooled center (SAPMAC) method. A critical defect model has been established to explain the growth and propagation of cracks during the sapphire growing process. It is demonstrated that the stress field depends on the growth rate, the ambient temperature and the crystallizing direction. High stresses always exist near the growth interfaces, at the shoulder-expanding locations, the tailing locations and the sites where the diameters undergo sharp changes. The maximum stresses always occur at the interface of seeds and crystals. Cracks often form in the critical defect region and spread in the m-planes and a-planes under applied tensile stresses during crystal growth. The experimental results have verified that with the improved system of crystal growth and well-controlled techniques, the large-sized sapphire crystals of high quality can be grown due to absence of cracks.

  6. 40 CFR 428.70 - Applicability; description of the large-sized general molded, extruded, and fabricated rubber...

    Science.gov (United States)

    2010-07-01

    ... large-sized general molded, extruded, and fabricated rubber plants subcategory. 428.70 Section 428.70... RUBBER MANUFACTURING POINT SOURCE CATEGORY Large-Sized General Molded, Extruded, and Fabricated Rubber... fabricated rubber plants subcategory. The following provisions of this subpart are applicable to...

  7. The Implication of Large Class Size in the Teaching and Learning of Business Education in Tertiary Institution in Ekiti State

    Science.gov (United States)

    Ayeni, Olapade Grace; Olowe, Modupe Oluwatoyin

    2016-01-01

    Large class size is one of the problems in the educational sector that developing nations have been grappling with. Nigeria as a developing nation is no exception. The purpose of this study is to provide views of both lecturers and students on large class size and how it affects teaching and learning in tertiary institutions in Ekiti State of…

  8. Indoor localization based on cellular telephony RSSI fingerprints containing very large numbers of carriers

    Directory of Open Access Journals (Sweden)

    Oussar Yacine

    2011-01-01

    Full Text Available Abstract A new approach to indoor localization is presented, based upon the use of Received Signal Strength (RSS fingerprints containing data from very large numbers of cellular base stations--up to the entire GSM band of over 500 channels. Machine learning techniques are employed to extract good quality location information from these high-dimensionality input vectors. Experimental results in a domestic and an office setting are presented, in which data were accumulated over a 1-month period in order to assure time robustness. Room-level classification efficiencies approaching 100% were obtained, using Support Vector Machines in one-versus-one and one-versus-all configurations. Promising results using semi-supervised learning techniques, in which only a fraction of the training data is required to have a room label, are also presented. While indoor RSS localization using WiFi, as well as some rather mediocre results with low-carrier count GSM fingerprints, have been discussed elsewhere, this is to our knowledge the first study to demonstrate that good quality indoor localization information can be obtained, in diverse settings, by applying a machine learning strategy to RSS vectors that contain the entire GSM band.

  9. Measurements of 222Rn and 220Rn with a Large Size Collector of Radon Progeny

    Institute of Scientific and Technical Information of China (English)

    Wu Qifan; Jia Wenyi; Fang Fang; Wang Jun; Cheng Jianping; Liu Guilin; Zhu Li

    2003-01-01

    Radon concentrations in high background radiation areas in the south are higher than those of others in China, especially 220Rn concentration is significantly high. Therefore, measurements of 222Rn and 220 Rn concentrations should be carried out there. This paper introduces a large size collector of radon progeny and its applications. The collector is a sheet of polyvinyl chloride fiber with electrostatics of (-500 V) - ( -700 V). Its size (60 mm in diameter) is larger than those of others (26 mm in diameter) that work with the same principle. The collector is more effective to adsorb radon progeny than most of others. The equipment of ZnS(Ag) Scintillation Counting System is available for large size collectors to detect radon progeny. Therefore, its sensitivity of measurement is higher than that of others.According to the different half lives of radon progeny, and based on both theory and experiments, a formula for discrimination and calculation of 222 Rn and 220Rn concentrations is deduced. The 222Rn and 220Rn concentrations were surveyed with electrostatic collectors of radon progeny on the campus of com-mercial school and some other areas in Hainan, southern China. Neither 222Rn nor 220Rn concentration was found significantly high. However, several faults underground were delineated. The collector is also used to study radon transportation. Results indicate that radon changes regularly with date when it has transported for a certain distance. Velocities of radon migration in the four media are quite different.Radon migrates more quickly in vertical tube than in the horizontal tube.

  10. Synthesis of Large-Sized Single-Crystal Hexagonal Boron Nitride Domains on Nickel Foils by Ion Beam Sputtering Deposition.

    Science.gov (United States)

    Wang, Haolin; Zhang, Xingwang; Liu, Heng; Yin, Zhigang; Meng, Junhua; Xia, Jing; Meng, Xiang-Min; Wu, Jinliang; You, Jingbi

    2015-12-22

    Large-sized single-crystal h-BN domains with a lateral size up to 100 μm are synthesized on Ni foils by ion-beam sputtering deposition. The nucleation density of h-BN is dramatically decreased by reducing the concentrations of both active sites and species on the Ni surface through a brief in situ pretreatment of the substrate and optimization of the growth parameters, enabling the growth of large-sized domains.

  11. —Does Demand Fall When Customers Perceive That Prices Are Unfair? The Case of Premium Pricing for Large Sizes

    OpenAIRE

    Eric T. Anderson; Duncan I. Simester

    2008-01-01

    We analyze a large-scale field test conducted with a mail-order catalog firm to investigate how customers react to premium prices for larger sizes of women's apparel. We find that customers who demand large sizes react unfavorably to paying a higher price than customers for small sizes. Further investigation suggests that these consumers perceive that the price premium is unfair. Overall, premium pricing led to a 6% to 8% decrease in gross profits.

  12. pH-activated size reduction of large compound nanoparticles for in vivo nucleus-targeted drug delivery.

    Science.gov (United States)

    Fan, Yanbin; Li, Chunyan; Li, Fuyou; Chen, Daoyong

    2016-04-01

    Nucleus-targeted drug delivery is a promising strategy for anticancer therapy, but in vivo nucleus-targeted drug delivery has been challenging. Limited by the channel size of the nucleopore, vehicles that enter the nucleus via the nucleopore actively should be small and decorated with nuclear localization signal (NLS). However, the small vehicle size may promote leakage of vehicles into normal tissues, and the positively-charged NLS can lead to strong non-specific interactions in vivo. In the present study, we demonstrate an in vivo nucleus-targeted drug delivery using large compound nanoparticles with detachable PEG shell. The nanoparticles are composed of PEG-benzoic imine-oligo-l-lysine/iridium(III) metallodrug complex and formed in a kinetically-controlled fashion. Under physiological conditions (pH 7.4), the nanoparticles are large (ca. 150 nm) and protected by an inert PEG shell. When internalized into intracellular acidic endo/lysosomes of cancer cells, the nanoparticles dissociate into smaller ones (ca. 40 nm) and the PEG chains detach due to the cleavage of the benzoic imine bond at low pH. The small nanoparticles, with exposure of the oligo-l-lysine after the detachment of the PEG shield, then translocate into the nucleus via the nucleopore due to the small size and nuclear localization ability of the oligo-l-lysine. Importantly, the small particles could significantly release the contained drug into the nucleus, leading to ca. 20-fold higher cytotoxicity compared to the native drug in vitro. Further in vivo application of the nucleus-targeting nano-system in a nude-mice model showed significant tumor inhibition and remarkable life-span elongation.

  13. Are large farms more efficient? Tenure security, farm size and farm efficiency: evidence from northeast China

    Science.gov (United States)

    Zhou, Yuepeng; Ma, Xianlei; Shi, Xiaoping

    2017-04-01

    How to increase production efficiency, guarantee grain security, and increase farmers' income using the limited farmland is a great challenge that China is facing. Although theory predicts that secure property rights and moderate scale management of farmland can increase land productivity, reduce farm-related costs, and raise farmer's income, empirical studies on the size and magnitude of these effects are scarce. A number of studies have examined the impacts of land tenure or farm size on productivity or efficiency, respectively. There are also a few studies linking farm size, land tenure and efficiency together. However, to our best knowledge, there are no studies considering tenure security and farm efficiency together for different farm scales in China. In addition, there is little study analyzing the profit frontier. In this study, we particularly focus on the impacts of land tenure security and farm size on farm profit efficiency, using farm level data collected from 23 villages, 811 households in Liaoning in 2015. 7 different farm scales have been identified to further represent small farms, median farms, moderate-scale farms, and large farms. Technical efficiency is analyzed with stochastic frontier production function. The profit efficiency is regressed on a set of explanatory variables which includes farm size dummies, land tenure security indexes, and household characteristics. We found that: 1) The technical efficiency scores for production efficiency (average score = 0.998) indicate that it is already very close to the production frontier, and thus there is little room to improve production efficiency. However, there is larger space to raise profit efficiency (average score = 0.768) by investing more on farm size expansion, seed, hired labor, pesticide, and irrigation. 2) Farms between 50-80 mu are most efficient from the viewpoint of profit efficiency. The so-called moderate-scale farms (100-150 mu) according to the governmental guideline show no

  14. Effect of surface acidity and pore size of Al-substituted plugs-containing SBA-15 and MCM-41 silicas on the polymerization of THF

    Institute of Scientific and Technical Information of China (English)

    Zhi Qi Jia; Ming Zhao; Chun Guang Gao; Yong Xiang Zhao

    2011-01-01

    We reported here the simultaneous influence of surface acidity and pore size of Al-substituted hexagonal mesoporous silicas (Aldoped plugs-containing SBA-15 and Al-doped MCM-41) on polymerization of THF.These materials were directly synthesized by introduced aluminum isopropoxide into reaction mixture including surfactant and siliceous precursor.Al-doped plugs-containing SBA-15 (denotes as PAS) samples not only possess typical two-step desorption isotherms,which implied PAS materials generated plugs in their mesochannel,but also exhibit larger pore size and thicker wall than that of Al-doped MCM-41 (denotes as ACM),which implied PAS would have a great advantage on catalytic reaction involving large molecular (e.g.polymer of TI-IF) in industrial point'of view.To investigate catalytic activity of PAS and ACM with moderate acidic sites the polymerization of THF in the presence of acetic anhydride was carded out.The results showed PAS exhibiting good performance on polymerization of THF.Such result could be related to the large pore size and moderate acidic sites.

  15. Myocardial infarct size and mortality depend on the time of day-a large multicenter study.

    Directory of Open Access Journals (Sweden)

    Stephane Fournier

    Full Text Available Different studies have shown circadian variation of ischemic burden among patients with ST-Elevation Myocardial Infarction (STEMI, but with controversial results. The aim of this study was to analyze circadian variation of myocardial infarction size and in-hospital mortality in a large multicenter registry.This retrospective, registry-based study was based on data from AMIS Plus, a large multicenter Swiss registry of patients who suffered myocardial infarction between 1999 and 2013. Peak creatine kinase (CK was used as a proxy measure for myocardial infarction size. Associations between peak CK, in-hospital mortality, and the time of day at symptom onset were modelled using polynomial-harmonic regression methods.6,223 STEMI patients were admitted to 82 acute-care hospitals in Switzerland and treated with primary angioplasty within six hours of symptom onset. Only the 24-hour harmonic was significantly associated with peak CK (p = 0.0001. The maximum average peak CK value (2,315 U/L was for patients with symptom onset at 23:00, whereas the minimum average (2,017 U/L was for onset at 11:00. The amplitude of variation was 298 U/L. In addition, no correlation was observed between ischemic time and circadian peak CK variation. Of the 6,223 patients, 223 (3.58% died during index hospitalization. Remarkably, only the 24-hour harmonic was significantly associated with in-hospital mortality. The risk of death from STEMI was highest for patients with symptom onset at 00:00 and lowest for those with onset at 12:00.As a part of this first large study of STEMI patients treated with primary angioplasty in Swiss hospitals, investigations confirmed a circadian pattern to both peak CK and in-hospital mortality which were independent of total ischemic time. Accordingly, this study proposes that symptom onset time be incorporated as a prognosis factor in patients with myocardial infarction.

  16. Inorganic ion composition in Tardigrada: cryptobionts contain a large fraction of unidentified organic solutes.

    Science.gov (United States)

    Halberg, Kenneth Agerlin; Larsen, Kristine Wulff; Jørgensen, Aslak; Ramløv, Hans; Møbjerg, Nadja

    2013-04-01

    Many species of tardigrades are known to tolerate extreme environmental stress, yet detailed knowledge of the mechanisms underlying the remarkable adaptations of tardigrades is still lacking, as are answers to many questions regarding their basic biology. Here, we present data on the inorganic ion composition and total osmotic concentration of five different species of tardigrades (Echiniscus testudo, Milnesium tardigradum, Richtersius coronifer, Macrobiotus cf. hufelandi and Halobiotus crispae) using high-performance liquid chromatography and nanoliter osmometry. Quantification of the ionic content indicates that Na(+) and Cl(-) are the principal inorganic ions in tardigrade fluids, albeit other ions, i.e. K(+), NH4(+), Ca(2+), Mg(2+), F(-), SO4(2-) and PO4(3-) were also detected. In limno-terrestrial tardigrades, the respective ions are concentrated by a large factor compared with that of the external medium (Na(+), ×70-800; K(+), ×20-90; Ca(2+) and Mg(2+), ×30-200; F(-), ×160-1040, Cl(-), ×20-50; PO4(3-), ×700-2800; SO4(2-), ×30-150). In contrast, in the marine species H. crispae, Na(+), Cl(-) and SO4(2-) are almost in ionic equilibrium with (brackish) salt water, while K(+), Ca(2+), Mg(2+) and F(-) are only slightly concentrated (×2-10). An anion deficit of ~120 mEq l(-1) in M. tardigradum and H. crispae indicates the presence of unidentified ionic components in these species. Body fluid osmolality ranges from 361±49 mOsm kg(-1) in R. coronifer to 961±43 mOsm kg(-1) in H. crispae. Concentrations of most inorganic ions are largely identical between active and dehydrated groups of R. coronifer, suggesting that this tardigrade does not lose large quantities of inorganic ions during dehydration. The large osmotic and ionic gradients maintained by both limno-terrestrial and marine species are indicative of a powerful ion-retentive mechanism in Tardigrada. Moreover, our data indicate that cryptobiotic tardigrades contain a large fraction of unidentified

  17. Genotype and fetal size affect maternal-fetal amino acid status and fetal endocrinology in Large White × Landrace and Meishan pigs.

    Science.gov (United States)

    Ashworth, Cheryl J; Nwagwu, Margaret O; McArdle, Harry J

    2013-01-01

    This study compared maternal plasma amino acid concentrations, placental protein secretion in vitro and fetal body composition and plasma amino acid and hormone concentrations in feto-placental units from the smallest and a normally-sized fetus carried by Large White × Landrace or Meishan gilts on Day 100 of pregnancy. Compared with Large White × Landrace, Meishan placental tissue secreted more protein and Meishan fetuses contained relatively more fat and protein, but less moisture. Fetal plasma concentrations of insulin, triiodothryonine, thyroxine and insulin-like growth factor (IGF)-II were higher in Meishan than Large White × Landrace fetuses. In both breeds, fetal cortisol concentrations were inversely related to fetal size, whereas concentrations of IGF-I were higher in average-sized fetuses. Concentrations of 10 amino acids were higher in Large White × Landrace than Meishan gilts, while glutamine concentrations were higher in Meishan gilts. Concentrations of alanine, aspartic acid, glutamic acid and threonine were higher in Meishan than Large White × Landrace fetuses. Average-sized fetuses had higher concentrations of asparagine, leucine, lysine, phenylalanine, threonine, tyrosine and valine than the smallest fetus. This study revealed novel genotype and fetal size differences in porcine maternal-fetal amino acid status and fetal hormone and metabolite concentrations.

  18. A large size ion beam figuring system for 1.2m astronomical telescopes fabrication

    Science.gov (United States)

    Xie, Xuhui; Yang, Bing; Zhou, Lin; Song, Ci; Hu, Hao

    2016-07-01

    An ion beam figuring system (KDIBF2000) for final figuring of large size optics has been designed and built by National University of Defense Technology in China. It can figure optics up to the maximum dimensions of 2.0m×2.0m×0.4m with five axes of servo-motion used to control ion source movement. For operational facility, there are two vacuum chambers with main work chamber and a small supplementary chamber isolated by a flapper valve. The main chamber has two work zones, which can meantime hold a large optics with Φ1.5m and a small optics with 0.4m. The small optics can be transferred through supplementary chamber with a moving vehicle. By this way, it is very convenient and economical to gain the material removal function and check the system's process performance. Now, this system has been gone into running to figure large SiC off-axis aspheric optics. Next step, a 1.2m SiC aspheric primary mirror will be figure by this system.

  19. Immunosuppressive Activity of Size-Controlled PEG-PLGA Nanoparticles Containing Encapsulated Cyclosporine A

    Directory of Open Access Journals (Sweden)

    Li Tang

    2012-01-01

    Full Text Available We encapsulated cyclosporine A (CsA in poly(ethylene glycol-b-poly(d,l-lactide-co-glycolide (PEG-PLGA nanoparticles (NPs by nanoprecipitation of CsA and PEG-PLGA. The resulting CsA/PEG-PLGA-NPs were <100 nm in diameter with a narrow particle size distribution. The NP size could be controlled by tuning the polymer concentration, solvent, or water/solvent ratio during formulation. The PEGylated NPs maintained non-aggregated in salt solution. Solid NPs lyoprotected with bovine serum albumin were prepared for the convenience of storage and transportation. The release kinetics of CsA (55.6% released on Day 1 showed potential for maintaining therapeutic CsA concentrations in vivo. In T-cell assays, both free CsA and CsA/PEG-PLGA-NPs suppressed T-cell proliferation and production of inflammatory cytokines dose dependently. In a mixed lymphocyte reaction assay, the IC50 values for free CsA and CsA/PEG-PLGA-NPs were found to be 30 and 35 ng/mL, respectively. This nanoparticulate CsA delivery technology constitutes a strong basis for future targeted delivery of immunosuppressive drugs with improved efficiency and potentially reduced toxicity.

  20. From mantle to critical zone: A review of large and giant sized deposits of the rare earth elements

    Directory of Open Access Journals (Sweden)

    M.P. Smith

    2016-05-01

    Full Text Available The rare earth elements are unusual when defining giant-sized ore deposits, as resources are often quoted as total rare earth oxide, but the importance of a deposit may be related to the grade for individual, or a limited group of the elements. Taking the total REE resource, only one currently known deposit (Bayan Obo would class as giant (>1.7 × 107 tonnes contained metal, but a range of others classify as large (>1.7 × 106 tonnes. With the exception of unclassified resource estimates from the Olympic Dam IOCG deposit, all of these deposits are related to alkaline igneous activity – either carbonatites or agpaitic nepheline syenites. The total resource in these deposits must relate to the scale of the primary igneous source, but the grade is a complex function of igneous source, magmatic crystallisation, hydrothermal modification and supergene enrichment during weathering. Isotopic data suggest that the sources conducive to the formation of large REE deposits are developed in subcontinental lithospheric mantle, enriched in trace elements either by plume activity, or by previous subduction. The reactivation of such enriched mantle domains in relatively restricted geographical areas may have played a role in the formation of some of the largest deposits (e.g. Bayan Obo. Hydrothermal activity involving fluids from magmatic to meteoric sources may result in the redistribution of the REE and increases in grade, depending on primary mineralogy and the availability of ligands. Weathering and supergene enrichment of carbonatite has played a role in the formation of the highest grade deposits at Mount Weld (Australia and Tomtor (Russia. For the individual REE with the current highest economic value (Nd and the HREE, the boundaries for the large and giant size classes are two orders of magnitude lower, and deposits enriched in these metals (agpaitic systems, ion absorption deposits may have significant economic impact in the near future.

  1. From mantle to critical zone:A review of large and giant sized deposits of the rare earth elements

    Institute of Scientific and Technical Information of China (English)

    M.P. Smith; K. Moore; D. Kavecsánszki; A.A. Finch; J. Kynicky; F. Wall

    2016-01-01

    The rare earth elements are unusual when defining giant-sized ore deposits, as resources are often quoted as total rare earth oxide, but the importance of a deposit may be related to the grade for indi-vidual, or a limited group of the elements. Taking the total REE resource, only one currently known deposit (Bayan Obo) would class as giant (>1.7 ? 107 tonnes contained metal), but a range of others classify as large (>1.7 ? 106 tonnes). With the exception of unclassified resource estimates from the Olympic Dam IOCG deposit, all of these deposits are related to alkaline igneous activity e either car-bonatites or agpaitic nepheline syenites. The total resource in these deposits must relate to the scale of the primary igneous source, but the grade is a complex function of igneous source, magmatic crystal-lisation, hydrothermal modification and supergene enrichment during weathering. Isotopic data suggest that the sources conducive to the formation of large REE deposits are developed in subcontinental lithospheric mantle, enriched in trace elements either by plume activity, or by previous subduction. The reactivation of such enriched mantle domains in relatively restricted geographical areas may have played a role in the formation of some of the largest deposits (e.g. Bayan Obo). Hydrothermal activity involving fluids from magmatic to meteoric sources may result in the redistribution of the REE and increases in grade, depending on primary mineralogy and the availability of ligands. Weathering and supergene enrichment of carbonatite has played a role in the formation of the highest grade deposits at Mount Weld (Australia) and Tomtor (Russia). For the individual REE with the current highest economic value (Nd and the HREE), the boundaries for the large and giant size classes are two orders of magnitude lower, and deposits enriched in these metals (agpaitic systems, ion absorption deposits) may have significant economic impact in the near future.

  2. The Friction Force Determination of Large-Sized Composite Rods in Pultrusion

    Science.gov (United States)

    Grigoriev, S. N.; Krasnovskii, A. N.; Kazakov, I. A.

    2014-08-01

    Nowadays, the simple pull-force models of pultrusion process are not suitable for large sized rods because they are not considered a chemical shrinkage and thermal expansion acting in cured material inside the die. But the pulling force of the resin-impregnated fibers as they travels through the heated die is essential factor in the pultrusion process. In order to minimize the number of trial-and-error experiments a new mathematical approach to determine the frictional force is presented. The governing equations of the model are stated in general terms and various simplifications are implemented in order to obtain solutions without extensive numerical efforts. The influence of different pultrusion parameters on the frictional force value is investigated. The results obtained by the model can establish a foundation by which process control parameters are selected to achieve an appropriate pull-force and can be used for optimization pultrusion process.

  3. Simulation of the main physical processes in remote laser penetration with large laser spot size

    Directory of Open Access Journals (Sweden)

    S. A. Khairallah

    2015-04-01

    Full Text Available A 3D model is developed to simulate remote laser penetration of a 1mm Aluminum metal sheet with large laser spot size (∼ 3x3cm2, using the ALE3D multi-physics code. The model deals with the laser-induced melting of the plate and the mechanical interaction between the solid and the melted part through plate elastic-plastic response. The effect of plate oscillations and other forces on plate rupture, the droplet formation mechanism and the influence of gravity and high laser power in further breaking the single melt droplet into many more fragments are analyzed. In the limit of low laser power, the numerical results match the available experiments. The numerical approach couples mechanical and thermal diffusion to hydrodynamics melt flow and accounts for temperature dependent material properties, surface tension, gravity and vapor recoil pressure.

  4. Comparative analysis on technologies between Chinese and American large-sized oil companies based on patentometrics

    Directory of Open Access Journals (Sweden)

    Zhao Qu

    2014-01-01

    Full Text Available Patent information is critical and important object to reflect differences in technology capacity; the paper makes statistical analysis on structural elements of five large-sized oil companies from America and China as collected in Derwent Innovations Index, and compare technical similarities and differences between such companies′ patents with visualization tools, by further research on academic classes, Derwent Class Code and co-occurrence of Manual Code. It is shown from the researches that Chinese enterprises is advantaged in growth in number of patents and cooperation rate, but their patents are characterized by poor influence, less relevance and connection between various disciplines, as well as relatively backward development of patented technology. Finally, according to current status of patents of Chinese and American oil companies, the paper proposes a series of recommendations and countermeasures for improvement in patents quality and future expansion in patented technology by Chinese oil companies.

  5. Surface plasmon resonance biosensor based on large size square-lattice photonic crystal fiber

    Science.gov (United States)

    Bing, Pibin; Li, Zhongyang; Yuan, Sheng; Yao, Jianquan; Lu, Ying

    2016-04-01

    A surface plasmon resonance biosensor based on large size square-lattice photonic crystal fiber has been designed and simulated by finite element method. The square-lattice airholes are first coated with a calcium fluoride layer to provide mode confinement, then a nanoscale gold layer is deposited to excite the plasmon mode, and finally, the sample is infiltrated into the holes. The numerical results reveal that the resonance properties are easily affected by many parameters. The refractive index resolution of corresponding sensor can reach 4.3 × 10-6 RIU when the optimum parameters are set as the radius of curvature of the airhole r = 2 μm, the thickness of the core struts c = 200 nm, the auxiliary dielectric layer s = 1 μm, and the gold film d = 40 nm. In addition, the effective area and nonlinear coefficient are calculated.

  6. A maturity model for SCPMS project-an empirical investigation in large sized Moroccan companies

    Directory of Open Access Journals (Sweden)

    Chafik Okar

    2011-03-01

    Full Text Available In the recent years many studies on maturity model have been carried out. Some refer specifically to maturity models for supply chain and performance measurement system. Starting from an analysis of the existing literature, the aim of this paper is to develop a maturity model for the supply chain performance measurement system (SCPMS project based on the concept of critical success factors (CSFs. This model will be validated by two approaches. The first is a pilot test of the model in a Moroccan supply chain to demonstrate his capacity of assessing the maturity of SCPMS project and whether it can develop an improvement roadmap. The second is an empirical investigation in large sized Moroccan companies by using a survey to depict whether it can evaluate the maturity of SCPMS project in different industries.

  7. Preform design of large sized profile ring rolling using main roll

    Energy Technology Data Exchange (ETDEWEB)

    Kim, H. J. [PSM Inc., Busan (Korea, Republic of); Kang, J. H. [Jac coupling, Busan (Korea, Republic of); Kang, S. S. [Busan Nat' l Univ., Busan (Korea, Republic of)

    2014-01-15

    This paper introduces a preform design method for a ring rolling process with an outer step. Underfilling is one of the general defects of the profile ring rolling process. It occurs when the deformation amount is small or step depth of the profiled region is large. To prevent underfilling, increasing the deformation amount or using a preform of size similar to that of the final product are required. Furthermore, the filling limit equation is suggested based on the shape factor and deformation ratio for preventing defects in the products. The filling limit equation has been derived through finite element analyses and production tests for four different cases. For verifying the suggested method, realsized profile rolling tests were performed, and test results were compared with the predictions of the equation.

  8. Oestrogen receptor genotypes and litter size in Hungarian Large White pigs.

    Science.gov (United States)

    Horogh, G; Zsolnai, A; Komiósi, I; Nyíri, A; Anton, I; Fésüs, L

    2005-02-01

    A total of 869 litter records of 226 Hungarian Large White sows have been analysed to investigate the possible use of the oestrogen receptor gene (ESR) as marker to improve litter size. First, second and later parities have been evaluated separately. Frequencies of A = 0.55 and B = 0.45 have been calculated for the two ESR alleles and the observed/ expected number of the three genotypes were as follows: AA: 71/69.1, AB: 108/111.8 and BB: 47/45.1. BB type first and later parity sows were superior to AB and AA sows for number born alive (NBA), total number of born (TNB) and the corrected number of weaned piglets (CNW), respectively.

  9. Asymmetric dihedral angle offsets for large-size lunar laser ranging retroreflectors

    Science.gov (United States)

    Otsubo, Toshimichi; Kunimori, Hiroo; Noda, Hirotomo; Hanada, Hideo; Araki, Hiroshi; Katayama, Masato

    2011-08-01

    The distribution of two-dimensional velocity aberration is off-centered by 5 to 6 microradians in lunar laser ranging, due to the stable measurement geometry in the motion of the Earth and the Moon. The optical responses of hollow-type retroreflectors are investigated through numerical simulations, especially focusing on large-size, single-reflector targets that can ultimately minimize the systematic error in future lunar laser ranging. An asymmetric dihedral angle offset, i.e. setting unequal angles between the three back faces, is found to be effective for retroreflectors that are larger than 100 mm in diameter. Our numerical simulation results reveal that the optimized return energy increases approximately 3.5 times more than symmetric dihedral angle cases, and the optimized dihedral angle offsets are 0.65-0.8 arcseconds for one angle, and zeroes for the other two angles.

  10. BASIC HYDRODYNAMICS CHARACTERISTICS OF CAVITY SPIRAL FLOW IN A LARGE SIZE LEVEL PIPE

    Institute of Scientific and Technical Information of China (English)

    NIU Zheng-ming; ZHANG Ming-yuan

    2005-01-01

    Based on the observation of a model test and in combination with some theoretical analysis, the researches of some basic hydrodynamics characteristics of cavity spiral flow in a large size level pipe with a shaft-inlet is presented in the paper, which include the basic flow pattern, formation condition of the cavity spiral flow, discharge Q, cavity diameter d0, wall pressure coefficient Cpw, velocity distribution, total energy dissipation rate η etc. The results show that the basic flow patterns can be divided into three zones according to the variations in cavity spiral flow when the upstream and downstream water level changes and that the basic hydrodynamics characteristics change with the flow pattern and have the different behaviour.

  11. A Ternary Solvent Method for Large-Sized Two-Dimensional Perovskites.

    Science.gov (United States)

    Chen, Junnian; Gan, Lin; Zhuge, Fuwei; Li, Huiqiao; Song, Jizhong; Zeng, Haibo; Zhai, Tianyou

    2017-02-20

    Recent reports demonstrate that a two-dimensional (2D) structural characteristic can endow perovskites with both remarkable photoelectric conversion efficiency and high stability, but the synthesis of ultrathin 2D perovskites with large sizes by facile solution methods is still a challenge. Reported herein is the controlled growth of 2D (C4 H9 NH3 )2 PbBr4 perovskites by a chlorobenzene-dimethylformide-acetonitrile ternary solvent method. The critical factors, including solvent volume ratio, crystallization temperature, and solvent polarity on the growth dynamics were systematically studied. Under optimum reaction condition, 2D (C4 H9 NH3 )2 PbBr4 perovskites, with the largest lateral dimension of up to 40 μm and smallest thickness down to a few nanometers, were fabricated. Furthermore, various iodine doped 2D (C4 H9 NH3 )2 PbBrx I4-x perovskites were accessed to tune the optical properties rationally.

  12. A Novel Read Scheme for Large Size One-Resistor Resistive Random Access Memory Array.

    Science.gov (United States)

    Zackriya, Mohammed; Kittur, Harish M; Chin, Albert

    2017-02-10

    The major issue of RRAM is the uneven sneak path that limits the array size. For the first time record large One-Resistor (1R) RRAM array of 128x128 is realized, and the array cells at the worst case still have good Low-/High-Resistive State (LRS/HRS) current difference of 378 nA/16 nA, even without using the selector device. This array has extremely low read current of 9.7 μA due to both low-current RRAM device and circuit interaction, where a novel and simple scheme of a reference point by half selected cell and a differential amplifier (DA) were implemented in the circuit design.

  13. A Novel Read Scheme for Large Size One-Resistor Resistive Random Access Memory Array

    Science.gov (United States)

    Zackriya, Mohammed; Kittur, Harish M.; Chin, Albert

    2017-01-01

    The major issue of RRAM is the uneven sneak path that limits the array size. For the first time record large One-Resistor (1R) RRAM array of 128x128 is realized, and the array cells at the worst case still have good Low-/High-Resistive State (LRS/HRS) current difference of 378 nA/16 nA, even without using the selector device. This array has extremely low read current of 9.7 μA due to both low-current RRAM device and circuit interaction, where a novel and simple scheme of a reference point by half selected cell and a differential amplifier (DA) were implemented in the circuit design. PMID:28186147

  14. Large-scale Hydrothermal Synthesis and Characterization of Size-controlled Lanthanum Hydroxide Nanorods

    Institute of Scientific and Technical Information of China (English)

    YI,Ran; ZHANG,Ning; SHI,Rongrong; LI,Yongbo; QIU Guanzhou; LIU Xiaohe

    2009-01-01

    Uniform lanthanum hydroxide nanorods were successfully synthesized in large quantities through a facile hydrothermal synthetic method, in which soluble lanthanum nitrate was used to supply the lanthanum source and triethylamine (TEA) was used as both alkaline agent and complexing agent. The influences of triethylamine amount, surfactant, reaction temperature and time on the size and shape of lanthanum hydroxide nanorods were investigated in detail. Trivalent rare earth ion doped lanthanum hydroxide nanorods were also obtained in this paper. The phase structures and morphologies of the as-prepared products were investigated in detail by X-ray diffraction (XRD), transmission electron microscopy (TEM), selected area electron diffraction (SAED) and high-resolution transmis-sion electron microscopy (HRTEM). The probable formation mechanism was proposed based on the experimental results.

  15. Larval assemblages of large and medium-sized pelagic species in the Straits of Florida

    Science.gov (United States)

    Richardson, David E.; Llopiz, Joel K.; Guigand, Cedric M.; Cowen, Robert K.

    2010-07-01

    Critical gaps in our understanding of the distributions, interactions, life histories and preferred habitats of large and medium-size pelagic fishes severely constrain the implementation of ecosystem-based, spatially structured fisheries management approaches. In particular, spawning distributions and the environmental characteristics associated with the early life stages are poorly documented. In this study, we consider the diversity, assemblages, and associated habitat of the larvae of large and medium-sized pelagic species collected during 2 years of monthly surveys across the Straits of Florida. In total, 36 taxa and 14,295 individuals were collected, with the highest diversity occurring during the summer and in the western, frontal region of the Florida Current. Only a few species (e.g. Thunnus obesus, T. alalunga, Tetrapturus pfluegeri) considered for this study were absent. Small scombrids (e.g. T. atlanticus, Katsuwonus pelamis, Auxis spp.) and gempylids dominated the catch and were orders of magnitude more abundant than many of the rare species (e.g. Thunnus thynnus,Kajikia albida). Both constrained (CCA) and unconstrained (NMDS) multivariate analyses revealed a number of species groupings including: (1) a summer Florida edge assemblage (e.g. Auxis spp., Euthynnus alleterattus, Istiophorus platypterus); (2) a summer offshore assemblage (e.g. Makaira nigricans, T. atlanticus, Ruvettus pretiosus, Lampris guttatus); (3) an ubiquitous assemblage (e.g. K. pelamis, Coryphaena hippurus, Xiphias gladius); and (4) a spring/winter assemblage that was widely dispersed in space (e.g. trachipterids). The primary environmental factors associated with these assemblages were sea-surface temperature (highest in summer-early fall), day length (highest in early summer), thermocline depth (shallowest on the Florida side) and fluorescence (highest on the Florida side). Overall, the results of this study provide insights into how a remarkable diversity of pelagic species

  16. Heritabilities and genetic and phenotypic correlations of litter uniformity and litter size in Large White sows

    Institute of Scientific and Technical Information of China (English)

    ZHANG Tian; ZHAO Ke-bin; WANG Li-xian; WANG Li-gang; SHI Hui-bi; YAN Hua; ZHANG Long-chao; LIU Xin; PU Lei; LIANG Jing; ZHANG Yue-bo

    2016-01-01

    Litter uniformity, which is usualy represented by within-litter weight coefifcient of variation at birth (CVB), could inlfuence litter performance of sows and the proiftability of pig enterprises. The objective of this study was to characterize CVB and its effect on other reproductive traits in Large White sows. Genetic parameters and genetic correlation of the reproductive traits, including CVB, within-litter weight coefifcient of variation at three weeks (CVT), total number born (TNB), number born alive (NBA), number born dead (NBD), gestation length (GL), piglet mortality at birth (M0), piglet mortality at three weeks (M3), total litter weight at birth (TLW0), and total litter weight at three weeks (TLW3) were estimated for 2032 Large White litters. The effects of parity and classiifed litter size on CVB, CVT, TNB, NBA, NBD, GL, M0, M3, TLW0, and TLW3 were also estimated. The heritabilities of these reproductive traits ranged from 0.06 to 0.17, with the lowest heritability for CVB and the highest heritability for TLW0. Phenotypic and genetic correlations between these reproductive traits were low to highly positive and negative (ranging from −0.03 to 0.93, and −0.53 to 0.93, respectively). The genetic correlations between TNB and CVB, and between M0 and CVB were 0.32 and 0.29, respectively. In addition, CVB was signiifcantly inlfuenced by parity and litter size class (P<0.05). Al the results suggest that piglet uniformity should be maintained in pig production practices and pig breeding programs.

  17. Large apparent electric size of solid-state nanopores due to spatially extended surface conduction.

    Science.gov (United States)

    Lee, Choongyeop; Joly, Laurent; Siria, Alessandro; Biance, Anne-Laure; Fulcrand, Rémy; Bocquet, Lydéric

    2012-08-08

    Ion transport through nanopores drilled in thin membranes is central to numerous applications, including biosensing and ion selective membranes. This paper reports experiments, numerical calculations, and theoretical predictions demonstrating an unexpectedly large ionic conduction in solid-state nanopores, taking its origin in anomalous entrance effects. In contrast to naive expectations based on analogies with electric circuits, the surface conductance inside the nanopore is shown to perturb the three-dimensional electric current streamlines far outside the nanopore in order to meet charge conservation at the pore entrance. This unexpected contribution to the ionic conductance can be interpreted in terms of an apparent electric size of the solid-state nanopore, which is much larger than its geometric counterpart whenever the number of charges carried by the nanopore surface exceeds its bulk counterpart. This apparent electric size, which can reach hundreds of nanometers, can have a major impact on the electrical detection of translocation events through nanopores, as well as for ionic transport in biological nanopores.

  18. Large 2D-arrays of size-controllable silver nanoparticles prepared by hybrid deposition

    Science.gov (United States)

    Dieu Thuy Ung, Thi; Hoa Nguyen, Thi; Liem Nguyen, Quang

    2016-09-01

    Two main results are presented in this paper. (i) Silver nanoparticles (AgNPs) with uniform size-distribution and controllability in the range of 20-50 nm were synthesized by seeding and growing at ambient conditions. The single-crystal Ag nano-seeds were created by reduction of AgNO3 in presence of citrate surfactant at 70 °C. Then, importantly, the fresh AgCl precursor was used in the presence of polyvinylpyrrolidone to adjust the reaction rate with ascorbic acid to generate Ag for growing on the surface of single-crystal Ag nano-seeds. The AgNPs size could be well-controlled by varying the amount of Ag nano-seeds while keeping the AgCl precursor concentration to be constant. (ii) The large 2D-arrays with homogeneous and dense monolayers of AgNPs were prepared on ITO substrates by hybrid method, in which the key technological point is the surface functionalization of AgNPs using mixed alkanethiols (dodecanethiol:octadecanethiol = 6:1). We have used the fabricated 2D-arrays from the 50 nm AgNPs as a surface enhanced Raman scattering substrate to take the Raman scattering spectra of rhodamine B (RhB), glucose and viral pathogen (H5N1) at very low concentrations of 10-10 M, 10-12 M and 4 ng μl-1, respectively.

  19. STATUS REPORT ON THE CMS FORWARD MUON UPGRADE WITH LARGE-SIZE TRIPLE-GEM DETECTORS

    CERN Document Server

    Barria, Patrizia

    2014-01-01

    For the LHC High Luminosity phase (HL-LHC) the CMS GEM Collaboration is planning to install new large size (990 x 440-220 mm2) triple-GEM detectors, equipped with a new readout system, in the forward region of the muon system (1.5 lt IηI lt 2.2) of the CMS detector. Combining triggering and tracking functionalities the new triple-Gas Electron Multiplier (GEM) chambers will not only improve the performance of the CMS muon trigger, but will also improve the muon identification and track reconstruction. With the addition of triple-GEM detectors the forward region of the CMS muon spectrometer will recover its originally planned redundancy. Starting from 2009 the CMS GEM Collaboration built several small and full size prototypes with different geometries, keeping improving the assembly techniques. All these prototypes have been tested in laboratories as well as with beam tests at the CERN SPS and at Fermilab. The results show that the triple-GEM detectors are a mature technology satisfying all the requirements ...

  20. Mie scattering by ensembles of particles with very large size parameters

    Science.gov (United States)

    Wolf, S.; Voshchinnikov, N. V.

    2004-09-01

    We present a computer program for the simulation of Mie scattering in case of arbitrarily large size parameters. The elements of the scattering matrix, efficiency factors as well as the corresponding cross-sections, the albedo and the scattering asymmetry parameter are calculated. Single particles as well as particle ensembles consisting of several components and particle size distributions can be considered. Program summary Title of program: miex Catalogue identifier: ADUD Program summary URL: http://cpc.cs.qub.ac.uk/summaries/ADUD Program obtainable from: CPC Program Library, Queen's University of Belfast, N. Ireland Computer for which the program is designed and others on which it has been tested: Computers: Any machine running standard FORTRAN 90; miex has been tested on an Intel Celeron processor (Redhat Linux 9.0, Intel Fortran Compiler 7.1), an Intel XEON processor (SuSE Linux 9.0, Intel Fortran Compiler 8.0), and a Sun-Blade-1000 (OS 8.5, Sun Workshop Compiler Fortran 90 2.0). Installations: standard Operating systems or monitors under which the program has been tested: Redhat Linux 9.0, SuSE Linux 9.0, Sun OS 8.5 Programming language used: Fortran 90 Memory required to execute with typical data: 1 MByte - several 100 MByte (see Appendix A for examples) No. of bits in a word: 8 No. of processors used: 1 Has the code been vectorized or parallelized?: No No. of lines in distributed program, including test data, etc.: 78238 No. of bytes in distributed program, including test data, etc.: 1015805 Distributed format: tar.gz Nature of the physical problem: Among a variety of applications, Mie scattering is of essential importance for the continuum radiative transfer in cosmic dust configurations. In this particular case, Mie theory describes the interaction of electromagnetic radiation with spherical dust grains on the basis of their complex refractive index and size parameter. Both, broad grain size distributions (radii a: nanometers-millimeters) and a very wide

  1. Simulation of Containment Pressurization in a Large Break-Loss of Coolant Accident Using Single-Cell and Multicell Models and CONTAIN Code

    Directory of Open Access Journals (Sweden)

    Omid Noori-Kalkhoran

    2016-10-01

    Full Text Available Since the inception of nuclear power as a commercial energy source, safety has been recognized as a prime consideration in the design, construction, operation, maintenance, and decommissioning of nuclear power plants. The release of radioactivity to the environment requires the failure of multiple safety systems and the breach of three physical barriers: fuel cladding, the reactor cooling system, and containment. In this study, nuclear reactor containment pressurization has been modeled in a large break-loss of coolant accident (LB-LOCA by programming single-cell and multicell models in MATLAB. First, containment has been considered as a control volume (single-cell model. In addition, spray operation has been added to this model. In the second step, the single-cell model has been developed into a multicell model to consider the effects of the nodalization and spatial location of cells in the containment pressurization in comparison with the single-cell model. In the third step, the accident has been simulated using the CONTAIN 2.0 code. Finally, Bushehr nuclear power plant (BNPP containment has been considered as a case study. The results of BNPP containment pressurization due to LB-LOCA have been compared between models, final safety analysis report, and CONTAIN code’s results.

  2. Simulation of containment pressurization in a large break-loss of coolant accident using single-cell and multicell models and CONTAIN code

    Energy Technology Data Exchange (ETDEWEB)

    Kalkahoran, Omid Noori; Ahangari, Rohollah [Reactor Research School, Nuclear Science and Technology Research Institute, Tehran (Iran, Islamic Republic of); Shirani, Amir Saied [Faculty of Engineering, Shahid Beheshti University, Tehran (Iran, Islamic Republic of)

    2016-10-15

    Since the inception of nuclear power as a commercial energy source, safety has been recognized as a prime consideration in the design, construction, operation, maintenance, and decommissioning of nuclear power plants. The release of radioactivity to the environment requires the failure of multiple safety systems and the breach of three physical barriers: fuel cladding, the reactor cooling system, and containment. In this study, nuclear reactor containment pressurization has been modeled in a large break-loss of coolant accident (LB-LOCA) by programming single-cell and multicell models in MATLAB. First, containment has been considered as a control volume (single-cell model). In addition, spray operation has been added to this model. In the second step, the single-cell model has been developed into a multicell model to consider the effects of the nodalization and spatial location of cells in the containment pressurization in comparison with the single-cell model. In the third step, the accident has been simulated using the CONTAIN 2.0 code. Finally, Bushehr nuclear power plant (BNPP) containment has been considered as a case study. The results of BNPP containment pressurization due to LB-LOCA have been compared between models, final safety analysis report, and CONTAIN code's results.

  3. Global hydroelastic analysis of ultra large container ships by improved beam structural model

    Science.gov (United States)

    Senjanović, Ivo; Vladimir, Nikola; Tomić, Marko; Hadžić, Neven; Malenica, Šime

    2014-12-01

    Some results on the hydroelasticity of ultra large container ships related to the beam structural model and restoring stiffness achieved within EU FP7 Project TULCS are summarized. An advanced thin-walled girder theory based on the modified Timoshenko beam theory for flexural vibrations with analogical extension to the torsional problem, is used for formulation of the beam finite element for analysis of coupled horizontal and torsional ship hull vibrations. Special attention is paid to the contribution of transverse bulkheads to the open hull stiffness, as well as to the reduced stiffness of the relatively short engine room structure. In addition two definitions of the restoring stiffness are considered: consistent one, which includes hydrostatic and gravity properties, and unified one with geometric stiffness as structural contribution via calm water stress field. Both formulations are worked out by employing the finite element concept. Complete hydroelastic response of a ULCS is performed by coupling 1D structural model and 3D hydrodynamic model as well as for 3D structural and 3D hydrodynamic model. Also, fatigue of structural elements exposed to high stress concentration is considered.

  4. Global hydroelastic analysis of ultra large container ships by improved beam structural model

    Directory of Open Access Journals (Sweden)

    Senjanović Ivo

    2014-12-01

    Full Text Available Some results on the hydroelasticity of ultra large container ships related to the beam structural model and restoring stiffness achieved within EU FP7 Project TULCS are summarized. An advanced thin-walled girder theory based on the modified Timoshenko beam theory for flexural vibrations with analogical extension to the torsional problem, is used for formulation of the beam finite element for analysis of coupled horizontal and torsional ship hull vibrations. Special attention is paid to the contribution of transverse bulkheads to the open hull stiffness, as well as to the reduced stiffness of the relatively short engine room structure. In addition two definitions of the restoring stiffness are considered: consistent one, which includes hydrostatic and gravity properties, and unified one with geometric stiffness as structural contribution via calm water stress field. Both formulations are worked out by employing the finite element concept. Complete hydroelastic response of a ULCS is performed by coupling 1D structural model and 3D hydrodynamic model as well as for 3D structural and 3D hydrodynamic model. Also, fatigue of structural elements exposed to high stress concentration is considered.

  5. A Large Rice Body-Containing Cyst Mimicking Infection following Total Hip Arthroplasty: A Case Report

    Directory of Open Access Journals (Sweden)

    Wael Bayoud

    2017-01-01

    Full Text Available Introduction. Soft tissue mass following total hip arthroplasty raises several differential diagnoses not limited to infection, hematoma, wear debris, malignancy, and bursitis. Rice body formation in the hip region is an uncommon process denoting a chronic inflammation. We report here the second case of its kind in the medical literature of a wide symptomatic rice-like body cyst complicating a total hip arthroplasty. Case Presentation. This is the case of an 82-year-old white female, presenting with a warm, red, and inflated groin five years after revision of right total hip arthroplasty. Surgical intervention reveals a large well circumscribed cyst containing well-organized rice-like bodies. This eventuality was never reported in differential diagnosis of hip periprosthetic soft tissue masses before. Conclusion. This case report helps widening the array of the differential diagnosis in patients presenting with a slow growing soft tissue mass following total hip arthroplasty, making rice-like bodies cyst a valid one to consider.

  6. Characteristics measurement methodology of the large-size autostereoscopic 3D LED display

    Science.gov (United States)

    An, Pengli; Su, Ping; Zhang, Changjie; Cao, Cong; Ma, Jianshe; Cao, Liangcai; Jin, Guofan

    2014-11-01

    Large-size autostereoscopic 3D LED displays are commonly used in outdoor or large indoor space, and have the properties of long viewing distance and relatively low light intensity at the viewing distance. The instruments used to measure the characteristics (crosstalk, inconsistency, chromatic dispersion, etc.) of the displays should have long working distance and high sensitivity. In this paper, we propose a methodology for characteristics measurement based on a distribution photometer with a working distance of 5.76m and the illumination sensitivity of 0.001 mlx. A display panel holder is fabricated and attached on the turning stage of the distribution photometer. Specific test images are loaded on the display separately, and the luminance data at the distance of 5.76m to the panel are measured. Then the data are transformed into the light intensity at the optimum viewing distance. According to definitions of the characteristics of the 3D displays, the crosstalk, inconsistency, chromatic dispersion could be calculated. The test results and analysis of the characteristics of an autostereoscopic 3D LED display are proposed.

  7. Use of telemetry X-ray techniques in large-size pictorial works

    Directory of Open Access Journals (Sweden)

    Jose Antonio Madrid Garcia

    2013-12-01

    Full Text Available In recent years, with the rise of digital technologies and the concurrent demise of related analog instrumentation, researchers in the field of cultural heritage have faced significant new challenges implementing digital solutions. Specifically, this shift has prompted the use of new protocols for the application of radiology in the study of art works.. However, due to this change, there has been a return to using older film formats, which is one of the problems that has already been solved using an industrial-type analogical system that allowed large-format X-ray support, and that was able to adapt to almost any surface. Therefore, this study attempts to rectify the limits of digital X-ray techniques by using telemetry X-ray techniques. At the Laboratory of Documentation and Registration (IRP, or Institute for the Heritage Restoration, based at the Universitat Politècnica de Valencia (UPV, Spain, mobile telemetry X-ray equipment has been designed and implemented that allows the adaptation of large-size pictorial works.

  8. The limits of weak selection and large population size in evolutionary game theory.

    Science.gov (United States)

    Sample, Christine; Allen, Benjamin

    2017-03-28

    Evolutionary game theory is a mathematical approach to studying how social behaviors evolve. In many recent works, evolutionary competition between strategies is modeled as a stochastic process in a finite population. In this context, two limits are both mathematically convenient and biologically relevant: weak selection and large population size. These limits can be combined in different ways, leading to potentially different results. We consider two orderings: the [Formula: see text] limit, in which weak selection is applied before the large population limit, and the [Formula: see text] limit, in which the order is reversed. Formal mathematical definitions of the [Formula: see text] and [Formula: see text] limits are provided. Applying these definitions to the Moran process of evolutionary game theory, we obtain asymptotic expressions for fixation probability and conditions for success in these limits. We find that the asymptotic expressions for fixation probability, and the conditions for a strategy to be favored over a neutral mutation, are different in the [Formula: see text] and [Formula: see text] limits. However, the ordering of limits does not affect the conditions for one strategy to be favored over another.

  9. Technology for Obtaining Large Size Complex Oxide Crystals for Experiments on Muon-Electron Conversion Registration in High Energy Physics

    Directory of Open Access Journals (Sweden)

    Gerasymov, Ya.

    2014-11-01

    Full Text Available Technological approaches for qualitative large size scintillation crystals growing based on rare-earth silicates are proposed. A method of iridium crucibles charging using eutectic phase instead of a oxyorthosilicate was developed.

  10. Reconstruction of large-size abdominal wall defect using biodegradable poly-p-dioxanone mesh: an experimental canine study

    National Research Council Canada - National Science Library

    Huang, Kenan; Ding, Xinyu; Lv, Benbo; Wei, Linyun; Sun, Juxian; Xu, Zhifei; Qin, Xiong; Tang, Hua

    2014-01-01

    ...) mesh for reconstructing large-size AWDs in an experimental canine model. Eighteen experimental canines were randomly and equally divided into three groups, namely, a PDO group, a Marlex group and a control group (n = 6 each...

  11. Spatial variation in particle number size distributions in a large metropolitan area

    Directory of Open Access Journals (Sweden)

    J. F. Mejía

    2007-11-01

    Full Text Available Air quality studies have indicated that particle number size distribution (NSD is unevenly spread in urban air. To date, these studies have focussed on differences in concentration levels between sampling locations rather than differences in the underlying geometries of the distributions. As a result, the existing information on the spatial variation of the NSD in urban areas remains incomplete. To investigate this variation in a large metropolitan area in the southern hemisphere, NSD data collected at nine different locations during different campaigns of varying duration were compared using statistical methods. The spectra were analysed in terms of their modal structures (the graphical representation of the number size distribution function, cumulative distribution and number median diameter (NMD. The study found that with the exception of one site all distributions were bimodal or suggestive of bimodality. In general, peak concentrations were below 30 nm and NMDs below 50 nm, except at a site dominated by diesel trucks, where it shifted to around 50 and 60 nm respectively. Ultrafine particles (UFPs contributed to 82–90% of the particle number, nanoparticles (<50 nm to around 60–70%, except at the diesel traffic site, where their contribution dropped to 50%. Statistical analyses found that the modal structures heterogeneously distributed throughout Brisbane whereas it was not always the case for the NMD. The discussion led to the following site classification: (1 urban sites dominated by petrol traffic, (2 urban sites affected by the proximity to the road and (3 an isolated site dominated by diesel traffic. Comparisons of weekday and weekend data indicated that, the distributions were not statistically different. The only exception occurred at one site, where there is a significant drop in the number of diesel buses on the weekend. The differences in sampling period between sites did not affect the results. The statistics instead suggested

  12. Large size superelastic SMA bars: heat treatment strategy, mechanical property and seismic application

    Science.gov (United States)

    Wang, Wei; Fang, Cheng; Liu, Jia

    2016-07-01

    This paper reports a comprehensive study on the mechanical performance of large size superelastic shape memory alloy (SMA) bars, with the main focus given to their potential applications for seismic-resistant connections. A series of practical issues, including heat treatment, mechanical property assessment, and connection design/evaluation, were discussed aiming to benefit both material and civil engineering communities. The study commenced with a detailed discussion on the heat treatment strategy for SMA bars and the resulting mechanical properties including strength/stiffness, self-centring ability, energy dissipation, and fractural resistance. It was observed that the mechanical performance of the bars were quite sensitive to both annealing temperature and duration, and size effect was also evident, resulting in different appropriate heat treatment procedures for the bars with varying diameters. The optimally heat-treated SMA bars were machined to the bolt form and were then used for two types of practical self-centring connections, namely, connection with all SMA bars and that with combined angles and SMA bars. Through conducting full-scale tests, both connections were shown to have stable and controllable hysteretic responses till 5% loading drift. Up to 3% drift, the self-centring performance was satisfactory for both connection types, but beyond that the presence of the angles could lead to accumulated residual rotation. Importantly, for both connections, the deformation was accommodated by the SMA bolts or angles, whereas no plastic deformation was observed at any other structural members. This confirmed the feasibility of using such connections for highly resilient structures where minimal repair work is required after earthquakes.

  13. Two Test Items to Explore High School Students' Beliefs of Sample Size When Sampling from Large Populations

    Science.gov (United States)

    Bill, Anthony; Henderson, Sally; Penman, John

    2010-01-01

    Two test items that examined high school students' beliefs of sample size for large populations using the context of opinion polls conducted prior to national and state elections were developed. A trial of the two items with 21 male and 33 female Year 9 students examined their naive understanding of sample size: over half of students chose a…

  14. Containment Performance Analysis with Large Break LOCA for EU-APR1400

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, Do Hyun; Lee, Keun Sung; Kim, Yong Soo [KHNP CRI, Daejeon (Korea, Republic of)

    2013-10-15

    In this paper for containment performance analysis, the containment pressurization analysis is performed and thermo-hydraulic response analysis of containment structure is carried out to provide basic understanding of containment transient states under a severe accident sequence. Especially, in EU-APR1400 design, to reduce containment pressure and temperature, Severe Accident Containment Spray System (SACSS) is designed to be actuated automatically when Core Exit Temperature (CET) reaches 922 K (649 .deg. C). The containment performance analysis was carried on LBLOCA sequence for EU-APR1400 with SACSS through MAAP code. If SACSS is actuated when CET reaches 922 K (649 .deg. C) , the containment pressure and temperature decrease to a sufficient low level. The predicted atmospheric pressure of containment will not exceed the ultimate pressure capacity (UPC) and have a sufficient margin to it even though the UPC of the reference plant (Shin-Kori Units 3 and 4) is used instead because the UPC calculation for EU-APR1400 has not been completed. The largest load on the containment by LBLOCA is estimated at 306.1 kPa. Thus the margin to UPC is estimated to be 330 % in comparison with 1.329 MPa as UPC for the reference plant.

  15. Viscous properties of ferrofluids containing both micrometer-size magnetic particles and fine needle-like particles

    Science.gov (United States)

    Ido, Yasushi; Nishida, Hitoshi; Iwamoto, Yuhiro; Yokoyama, Hiroki

    2017-06-01

    Ferrofluids containing both micrometer-size spherical magnetic particles and nanometer-size needle-like nonmagnetic hematite particles were newly produced. Average length of long axis of the needle-like nonmagnetic particles was 194 nm and the aspect ratio was 8.3. Shear stress and viscosity were measured using the rheometer with the additional equipment for viscosity measurements in the presence of magnetic field. When the total volume fraction of particles in the fluid is constant (0.30), there is the specific mixing ratio of the particles to increase viscosity of the fluid drastically in the absence of magnetic field due to the percolation phenomenon. The fluid of the specific mixing ratio shows solid-like behavior even in the absence of magnetic field. Mixing the needle-like nonmagnetic particles causes strong yield stress and strong viscous force in the presence of magnetic field.

  16. Bra band size measurements derived from three-dimensional scans are not accurate in women with large, ptotic breasts.

    Science.gov (United States)

    McGhee, Deirdre E; Ramsay, Lauren G; Coltman, Celeste E; Gho, Sheridan A; Steele, Julie R

    2017-07-12

    This study investigated differences in standard measurements used to determine bra size, under-bust chest circumference (UBCC) and over-bust chest circumference (OBCC), measured from a three-dimensional scan (hand-held scanner) compared to the direct measurement in 111 women (age 21-56 years; right breast volume 57-1672 mL; bra size 10A-18G). Bland-Altman plots of UBCC measurements showed a large positive bias and wide limits of agreement (12 cm; -4.6 to 28 cm), which increased as band size increased but decreased when the breasts were digitally removed from the scan prior to the UBCC measurement. The difference in UBCC measurements determined from scans compared to direct measurement had a strong positive correlation with breast volume and breast ptotis. The OBCC measurements showed a small positive bias (2.4 cm; -3.4 to 8.4), consistent across the range of bra sizes. Bra band size measurements determined from three-dimensional scans can be inaccurate in women with large, ptotic breasts. Practitioner Summary: We investigated potential errors in anthropometric data derived from three-dimensional scans used for bra design and fit. Bra band size measurements taken from three-dimensional scans were over-estimated in women with large breasts, whereas bra cup size measurements were accurate to within one-cup size across the entire range of bra sizes.

  17. Strength and fatigue testing of large size wind turbines rotors. Vol. II: Full size natural vibration and static strength test, a reference case

    Energy Technology Data Exchange (ETDEWEB)

    Arias, F.; Soria, E.

    1996-12-01

    This report shows the methods and procedures selected to define a strength test for large size wind turbine, anyway in particular it application on a 500 kW blade and it results obtained in the test carried out in july of 1995 in Asinel`s test plant (Madrid). Henceforth, this project is designed in an abbreviate form whit the acronym SFAT. (Author)

  18. Novel processing of bioglass ceramics from silicone resins containing micro- and nano-sized oxide particle fillers.

    Science.gov (United States)

    Fiocco, L; Bernardo, E; Colombo, P; Cacciotti, I; Bianco, A; Bellucci, D; Sola, A; Cannillo, V

    2014-08-01

    Highly porous scaffolds with composition similar to those of 45S5 and 58S bioglasses were successfully produced by an innovative processing method based on preceramic polymers containing micro- and nano-sized fillers. Silica from the decomposition of the silicone resins reacted with the oxides deriving from the fillers, yielding glass ceramic components after heating at 1000°C. Despite the limited mechanical strength, the obtained samples possessed suitable porous architecture and promising biocompatibility and bioactivity characteristics, as testified by preliminary in vitro tests.

  19. Quantum Interference Control of Ballistic Magneto- resistance in a Magnetic Nanowire Containing Two Atomic- Size Domain Walls

    Directory of Open Access Journals (Sweden)

    V. Fallahi

    2012-06-01

    Full Text Available The magnetoresistance of a one-dimensional electron gas in a metallic ferromagnetic nanowire containing two atomic-size domain walls has been investigated in the presence of spin-orbit interaction. The magnetoresistance is calculated in the ballistic regime, within the Landauer-Büttiker formalism. It has been demonstrated that the conductance of a magnetic nanowire with double domain walls can be controlled through the domain walls separation. Also, we have represented another alternative way that enables us to handle easily the magnetoresistance of such a system as well as its conductance by utilizing the Rashba-type spin-orbit interaction induced by the external gates.

  20. Prototyping a large field size IORT applicator for a mobile linear accelerator

    Science.gov (United States)

    Janssen, Rogier W. J.; Faddegon, Bruce A.; Dries, Wim J. F.

    2008-04-01

    The treatment of large tumors such as sarcomas with intra-operative radiotherapy using a Mobetron® is often complicated because of the limited field size of the primary collimator and the available applicators (max Ø100 mm). To circumvent this limitation a prototype rectangular applicator of 80 × 150 mm2 was designed and built featuring an additional scattering foil located at the top of the applicator. Because of its proven accuracy in modeling linear accelerator components the design was based on the EGSnrc Monte Carlo simulation code BEAMnrc. First, the Mobetron® treatment head was simulated both without an applicator and with a standard 100 mm applicator. Next, this model was used to design an applicator foil consisting of a rectangular Al base plate covering the whole beam and a pyramid of four stacked cylindrical slabs of different diameters centered on top of it. This foil was mounted on top of a plain rectangular Al tube. A prototype was built and tested with diode dosimetry in a water tank. Here, the prototype showed clinically acceptable 80 × 150 mm2 dose distributions for 4 MeV, 6 MeV and 9 MeV, obviating the use of complicated multiple irradiations with abutting field techniques. In addition, the measurements agreed well with the MC simulations, typically within 2%/1 mm.

  1. Large-sized cylinder of Bi-2223/Ni meshes composite bulk for current lead

    Energy Technology Data Exchange (ETDEWEB)

    Sakamoto, M. [Department of Electrical Engineering, Kogakuin University, 2665-1, Nakano, Hachioji, Tokyo 192-0015 (Japan); Yoshizawa, S. [Department of Environmental Systems, Meisei University, 2-1-1, Hodokubo, Hino, Tokyo 191-8506 (Japan)]. E-mail: yoshizaw@es.meisei-u.ac.jp; Hishinuma, Y. [Fusion Engineering Research Center, National Institute for Fusion Science, 322-6, Oroshi, Toki, Gifu 509-5202 (Japan); Nishimura, A. [Fusion Engineering Research Center, National Institute for Fusion Science, 322-6, Oroshi, Toki, Gifu 509-5202 (Japan); Yamazaki, S. [Department of Electrical Engineering, Kogakuin University, 2665-1, Nakano, Hachioji, Tokyo 192-0015 (Japan); Kojima, S. [Department of Electrical Engineering, Kogakuin University, 2665-1, Nakano, Hachioji, Tokyo 192-0015 (Japan)

    2006-10-01

    In order to improve the critical current density (J {sub c}) and mechanical property of Bi-2223 sintered bulk, Ni wire meshes were added in the bulk. For fabricating large-sized cylindrical Bi-2223/Ni meshes composite, composing meshes are easy to produce compared with adding a lot of wires. The mesh concentration was 18 x 18 meshes/cm{sup 2} using Ni wires of 0.25 mm in diameter. The Ni meshes were plated with Ag by 0.03 mm in thickness. We prepared the cylindrical sintered bulk for a current lead, 32 mm in outer diameter, 2 mm in thickness and 110 mm in length using a cold isostatic pressing (CIP) method. The samples were sintered at 845 deg. C for 50 h. After treatment again with CIP as an intermediate pressing, the samples were re-sintered. Small species were cut from the cylinder for measurement of critical current density (J {sub c}) at 77 K under self-field. There existed higher J {sub c} portions and low J {sub c} portions in the composite cylinder. Scanning electron microscope (SEM) observation showed that highly c-axis oriented and densely structured Bi-2223 plate-like grains could be formed around the interfacial region between the superconducting oxide and the Ag-plated Ni wires. There observed structural dislocation, which lead to low J {sub c} portions in the cylinder.

  2. Hydrophobic polymers modification of mesoporous silica with large pore size for drug release

    Energy Technology Data Exchange (ETDEWEB)

    Zhu Shenmin, E-mail: smzhu@sjtu.edu.c [Shanghai Jiao Tong University, State Key Lab of Metal Matrix Composites (China); Zhang Di; Yang Na [Fudan University, Ministry of Education, Key Lab of Molecular Engineering of Polymers (China)

    2009-04-15

    Mesostructure cellular foam (MCF) materials were modified with hydrophobic polyisoprene (PI) through free radical polymerization in the pores network, and the resulting materials (MCF-PI) were investigated as matrices for drug storage. The successful synthesis of PI inside MCF was characterized by Fourier transform infrared (FT-IR), hydrogen nuclear magnetic resonance ({sup 1}H NMR), X-ray diffraction patterns (XRD) and nitrogen adsorption/desorption measurements. It was interesting to find the resultant system held a relatively large pore size (19.5 nm) and pore volume (1.02 cm{sup 3} g{sup -1}), which would benefit for drug storage. Ibuprofen (IBU) and vancomycin were selected as model drugs and loaded onto unmodified MCF and modified MCF (MCF-PI). The adsorption capacities of these model drugs on MCF-PI were observed increase as compared to that of on pure MCF, due to the trap effects induced by polyisoprene chains inside the pores. The delivery system of MCF-PI was found to be more favorable for the adsorption of IBU (31 wt%, IBU/silica), possibly attributing to the hydrophobic interaction between IBU and PI formed on the internal surface of MCF matrix. The release of drug through the porous network was investigated by measuring uptake and release of IBU.

  3. Large-area, size-tunable Si nanopillar arrays with enhanced antireflective and plasmonic properties.

    Science.gov (United States)

    Niu, Lihong; Jiang, Xiaohong; Zhao, Yaolong; Ma, Haiguang; Yang, Jingjing; Cheng, Ke; Du, Zuliang

    2016-08-01

    In this paper, a novel method using the modified Langmuir-Blodgett and float-transfer techniques was introduced to construct the perfect PS monolayer nanosphere template with large area up to cm(2). Based on such templates, the diameter, length, packing density, and the shape of Si nanopillar arrays (Si NPAs) could be precisely controlled and tuned through the modified nanosphere lithography combined with a metal-assisted chemical etching (NSL-MACE) method. Manipulation of the etching time can effectively avoid permanent deformation/clumping to generate size-tunable Si NPAs. The optical properties of the Si NPAs can be controlled by the Si NPA morphologies resulting from the different reactive ion etching (RIE) time and chemical etching time. The enhanced antireflective property and electromagnetic field effect of Au/Si NPAs were proved by the results. The new modified NSL-MACE technique with the capability of scale-up fabrication of Si NPAs would be helpful for potential applications in optoelectronic devices.

  4. Impact of Large Family Size on the Reproductive Health of Women at Palosi Peshawar

    Directory of Open Access Journals (Sweden)

    Anwar Alam

    2012-04-01

    Full Text Available This study was under taken on, “Impact of large family size on the reproductive health of women at Palosi Peshawar”. For this study the researcher contacted 30 women respondents on purposive sampling basis out of 332 married women in Palosi Peshawar (DCR 1998 Peshawar. Interview schedule was used as a tool of data collection for illiterate respondents while questionnaire was used for educated respondents. The study indicates that due to illiteracy and ignorance, the women of rural areas are unaware about the complications, facilities, problems and precautions. They faced work pressure during pregnancy due to joint family system. Mostly the respondents were facing health problems during pregnancy due to the non-availability of female doctors, LHV/LHW were not visiting their home, no facilities of maternity clinics and lack of medicines. The desire for more children affected the mother child health and led to physical, psychological problems and also affect the reproductive health of woman and also caused excessive deliveries, which were harmful to mother child health. The reproductive problems of respondents can be resolved through proper nutrition, availability of maternity clinics, reproductive health centers, family health & welfare centers, quality contraceptives and proper medicines.

  5. Fabrication of large size alginate beads for three-dimensional cell-cluster culture

    Science.gov (United States)

    Zhang, Zhengtao; Ruan, Meilin; Liu, Hongni; Cao, Yiping; He, Rongxiang

    2017-08-01

    We fabricated large size alginate beads using a simple microfluidic device under a co-axial injection regime. This device was made by PDMS casting with a mold formed by small diameter metal and polytetrafluorothylene tubes. Droplets of 2% sodium alginate were generated in soybean oil through the device and then cross-linked in a 2% CaCl2 solution, which was mixed tween80 with at a concentration of 0.4 to 40% (w/v). Our results showed that the morphology of the produced alginate beads strongly depends on the tween80 concentration. With the increase of concentration of tween80, the shape of the alginate beads varied from semi-spherical to tailed-spherical, due to the decrease of interface tension between oil and cross-link solution. To access the biocompatibility of the approach, MCF-7 cells were cultured with the alginate beads, showing the formation of cancer cells clusters which might be useful for future studies.

  6. The Optical System for the Large Size Telescope of the Cherenkov Telescope Array

    CERN Document Server

    Hayashida, M; Teshima, M; de Almeida, U Barres; Chikawa, M; Cho, N; Fukami, S; Gadola, A; Hanabata, Y; Horns, D; Jablonski, C; Katagiri, H; Kagaya, M; Ogino, M; Okumura, A; Saito, T; Stadler, R; Steiner, S; Straumann, U; Vollhardt, A; Wetteskind, H; Yamamoto, T; Yoshida, T

    2015-01-01

    The Large Size Telescope (LST) of the Cherenkov Telescope Array (CTA) is designed to achieve a threshold energy of 20 GeV. The LST optics is composed of one parabolic primary mirror 23 m in diameter and 28 m focal length. The reflector dish is segmented in 198 hexagonal, 1.51 m flat to flat mirrors. The total effective reflective area, taking into account the shadow of the mechanical structure, is about 368 m$^2$. The mirrors have a sandwich structure consisting of a glass sheet of 2.7 mm thickness, aluminum honeycomb of 60 mm thickness, and another glass sheet on the rear, and have a total weight about 47 kg. The mirror surface is produced using a sputtering deposition technique to apply a 5-layer coating, and the mirrors reach a reflectivity of $\\sim$94% at peak. The mirror facets are actively aligned during operations by an active mirror control system, using actuators, CMOS cameras and a reference laser. Each mirror facet carries a CMOS camera, which measures the position of the light spot of the optical ...

  7. Innovative heating of large-size automotive Li-ion cells

    Science.gov (United States)

    Yang, Xiao-Guang; Liu, Teng; Wang, Chao-Yang

    2017-02-01

    Automotive Li-ion cells are becoming much larger and thicker in order to reduce the cell count and increase battery reliability, posing a new challenge to battery heating from the cold ambient due to poor through-plane heat transfer across a cell's multiple layers of electrodes and separators. In this work, widely used heating methods, including internal heating using the cell's resistance and external heating by resistive heaters, are compared with the recently developed self-heating Li-ion battery (SHLB) with special attention to the heating speed and maximum local temperature critical to battery safety. Both conventional methods are found to be slow due to low heating power required to maintain battery safety. The heating power in the external heating method is limited by the risk of local over-heating, in particular for thick cells. As a result, the external heating method is restricted to ∼20 min slow heating for a 30 °C temperature rise. In contrast, the SHLB is demonstrated to reach a heating speed of 1-2 °C/sec, ∼40 times faster for large-size thick cells, with nearly 100% heating efficiency and spatially uniform heating free from safety concerns.

  8. Development of the Photomultiplier-Tube Readout System for the CTA Large Size Telescope

    CERN Document Server

    Kubo, H; Awane, Y; Bamba, A; Barcelo, M; Barrio, J A; Blanch, O; Boix, J; Delgado, C; Fink, D; Gascon, D; Gunji, S; Hagiwara, R; Hanabata, Y; Hatanaka, K; Hayashida, M; Ikeno, M; Kabuki, S; Katagiri, H; Kataoka, J; Konno, Y; Koyama, S; Kishimoto, T; Kushida, J; Martinez, G; Masuda, S; Miranda, J M; Mirzoyan, R; Mizuno, T; Nagayoshi, T; Nakajima, D; Nakamori, T; Ohoka, H; Okumura, A; Orito, R; Saito, T; Sanuy, A; Sasaki, H; Sawada, M; Schweizer, T; Sugawara, R; Sulanke, K -H; Tajima, H; Tanaka, M; Tanaka, S; Tejedor, L A; Terada, Y; Teshima, M; Tokanai, F; Tsuchiya, Y; Uchida, T; Ueno, H; Umehara, K; Yamamoto, T

    2013-01-01

    We have developed a prototype of the photomultiplier tube (PMT) readout system for the Cherenkov Telescope Array (CTA) Large Size Telescope (LST). Two thousand PMTs along with their readout systems are arranged on the focal plane of each telescope, with one readout system per 7-PMT cluster. The Cherenkov light pulses generated by the air showers are detected by the PMTs and amplified in a compact, low noise and wide dynamic range gain block. The output of this block is then digitized at a sampling rate of the order of GHz using the Domino Ring Sampler DRS4, an analog memory ASIC developed at Paul Scherrer Institute. The sampler has 1,024 capacitors per channel and four channels are cascaded for increased depth. After a trigger is generated in the system, the charges stored in the capacitors are digitized by an external slow sampling ADC and then transmitted via Gigabit Ethernet. An onboard FPGA controls the DRS4, trigger threshold, and Ethernet transfer. In addition, the control and monitoring of the Cockcrof...

  9. Silicon Photomultiplier Research and Development Studies for the Large Size Telescope of the Cherenkov Telescope Array

    CERN Document Server

    Rando, Riccardo; Dazzi, Francesco; De Angelis, Alessandro; Dettlaff, Antonios; Dorner, Daniela; Fink, David; Fouque, Nadia; Grundner, Felix; Haberer, Werner; Hahn, Alexander; Hermel, Richard; Korpar, Samo; Mezek, Gašper Kukec; Maier, Ronald; Manea, Christian; Mariotti, Mosè; Mazin, Daniel; Mehrez, Fatima; Mirzoyan, Razmik; Podkladkin, Sergey; Reichardt, Ignasi; Rhode, Wolfgang; Rosier, Sylvie; Schultz, Cornelia; Stella, Carlo; Teshima, Masahiro; Wetteskind, Holger; Zavrtanik, Marko

    2015-01-01

    The Cherenkov Telescope Array (CTA) is the the next generation facility of imaging atmospheric Cherenkov telescopes; two sites will cover both hemispheres. CTA will reach unprecedented sensitivity, energy and angular resolution in very-high-energy gamma-ray astronomy. Each CTA array will include four Large Size Telescopes (LSTs), designed to cover the low-energy range of the CTA sensitivity ($\\sim$20 GeV to 200 GeV). In the baseline LST design, the focal-plane camera will be instrumented with 265 photodetector clusters; each will include seven photomultiplier tubes (PMTs), with an entrance window of 1.5 inches in diameter. The PMT design is based on mature and reliable technology. Recently, silicon photomultipliers (SiPMs) are emerging as a competitor. Currently, SiPMs have advantages (e.g. lower operating voltage and tolerance to high illumination levels) and disadvantages (e.g. higher capacitance and cross talk rates), but this technology is still young and rapidly evolving. SiPM technology has a strong pot...

  10. Investigation of Low-Cost Surface Processing Techniques for Large-Size Multicrystalline Silicon Solar Cells

    Directory of Open Access Journals (Sweden)

    Yuang-Tung Cheng

    2010-01-01

    Full Text Available The subject of the present work is to develop a simple and effective method of enhancing conversion efficiency in large-size solar cells using multicrystalline silicon (mc-Si wafer. In this work, industrial-type mc-Si solar cells with area of 125×125 mm2 were acid etched to produce simultaneously POCl3 emitters and silicon nitride deposition by plasma-enhanced chemical vapor deposited (PECVD. The study of surface morphology and reflectivity of different mc-Si etched surfaces has also been discussed in this research. Using our optimal acid etching solution ratio, we are able to fabricate mc-Si solar cells of 16.34% conversion efficiency with double layers silicon nitride (Si3N4 coating. From our experiment, we find that depositing double layers silicon nitride coating on mc-Si solar cells can get the optimal performance parameters. Open circuit (Voc is 616 mV, short circuit current (Jsc is 34.1 mA/cm2, and minority carrier diffusion length is 474.16 μm. The isotropic texturing and silicon nitride layers coating approach contribute to lowering cost and achieving high efficiency in mass production.

  11. A comparison of workplace safety perceptions among financial decision-makers of medium- vs. large-size companies.

    Science.gov (United States)

    Huang, Yueng-Hsiang; Leamon, Tom B; Courtney, Theodore K; Chen, Peter Y; DeArmond, Sarah

    2011-01-01

    This study, through a random national survey in the U.S., explored how corporate financial decision-makers perceive important workplace safety issues as a function of the size of the company for which they worked (medium- vs. large-size companies). Telephone surveys were conducted with 404 U.S. corporate financial decision-makers: 203 from medium-size companies and 201 from large companies. Results showed that the patterns of responding for participants from medium- and large-size companies were somewhat similar. The top-rated safety priorities in resource allocation reported by participants from both groups were overexertion, repetitive motion, and bodily reaction. They believed that there were direct and indirect costs associated with workplace injuries and for every dollar spent improving workplace safety, more than four dollars would be returned. They perceived the top benefits of an effective safety program to be predominately financial in nature - increased productivity and reduced costs - and the safety modification participants mentioned most often was to have more/better safety-focused training. However, more participants from large- than medium-size companies reported that "falling on the same level" was the major cause of workers' compensation loss, which is in line with industry loss data. Participants from large companies were more likely to see their safety programs as better than those of other companies in their industries, and those of medium-size companies were more likely to mention that there were no improvements needed for their companies.

  12. Fabrication of large-sized two-dimensional ordered surface array with well-controlled structure via colloidal particle lithography.

    Science.gov (United States)

    Meng, Xiaohui; Zhang, Xinping; Ye, Lei; Qiu, Dong

    2014-06-17

    Epoxy resin coated glass slides were used for colloidal particle lithography, in order to prepare well-defined 2D surface arrays. Upon the assistance of a large-sized 2D colloidal single crystal as template, centimeter-sized ordered surface arrays of bowl-like units were obtained. Systematic studies revealed that the parameters of obtained surface arrays could be readily controlled by some operational factors, such as temperature, epoxy resin layer thickness, and template particle size. With epoxy resin substituting for normal linear polymer, the height/diameter ratio of bowls in the formed surface arrays can be largely increased. With further reactive plasma etching, the parameters of ordered surface arrays could be finely tuned through controlling etching time. This study provides a facile way to prepare large-sized 2D surface arrays with tunable parameters.

  13. Container Type Influences the Relative Abundance, Body Size, and Susceptibility of Ochlerotatus triseriatus (Diptera: Culicidae) to La Crosse Virus.

    Science.gov (United States)

    Bara, Jeffrey J; Muturi, Ephantus J

    2015-05-01

    Ochlerotatus triseriatus (Say), the primary vector of La Crosse virus (LAC), develops in a variety of natural and artificial aquatic containers where it often co-occurs with larvae of other mosquito species. We conducted a field study at two woodlots (South Farms and Trelease Woods) in Urbana, IL, to examine how container type influences vector abundance, body size, and susceptibility to LAC. Mosquito pupae were collected from tree holes, plastic bins, and waste tires, and eclosing adults were identified to species morphologically. Oc. triseriatus and Ochlerotatus japonicus (Theobald) females were orally challenged with LAC and midgut infection rate, disseminated infection rate, and body titer were determined by reverse-transcriptase real-time PCR. Oc. triseriatus was the dominant species collected in tree holes while Oc. japonicus and Culex restuans (Theobald) were mostly dominant in artificial containers. Female Oc. triseriatus and Oc. japonicus collected from plastic bins were significantly larger than those collected from tree holes or waste tires. Oc. japonicus females from South Farms were also significantly larger than those from Trelease Woods. Oc. triseriatus females collected from plastic bins and waste tires were significantly more susceptible to LAC infection relative to females collected from tree holes. In addition, Oc. triseriatus females from waste tires had significantly higher LAC titer relative to Oc. triseriatus from tree holes. For each container type and study site, wing length was not correlated to infection or dissemination rates. These findings suggest that the container type in which Oc.triseriatus develop may contribute to the spatial and temporal dynamics of LAC transmission.

  14. Rheological and droplet size analysis of W/O/W multiple emulsions containing low concentrations of polymeric emulsifiers

    Directory of Open Access Journals (Sweden)

    DRAGANA D. VASILJEVIĆ

    2009-07-01

    Full Text Available Multiple emulsions are complex dispersion systems which have many potential applications in pharmaceutics, cosmetics and the food industry. In practice, however, significant problems may arise because of their thermodynamic instability. In this study, W/O/W multiple emulsion systems containing low concentration levels of lipophilic polymeric primary emulsifiers cetyl dimethicone copolyol and PEG–30 dipolyhydroxystearate were evaluated. The concentrations of the primary emulsifiers were set at 1.6 and 2.4 % w/w in the final emulsions. Rheological and droplet size analysis of the investigated samples showed that the type and concentration of the primary lipophilic polymeric emulsifier markedly affected the characteristics of the multiple emulsions. The multiple emulsion prepared with 2.4 % w/w PEG–30 dipolyhydroxystearate as the primary emulsifier exhibited the highest apparent viscosity, yield stress and elastic modulus values, as well as the smallest droplet size. Furthermore, these parameters remained relatively constant over the study period, confirming the high stability of the investigated sample. The results obtained indicate that the changes observed in the investigated samples over time could be attributed to the swelling/breakdown mechanism of the multiple droplets. Such changes could be adequately monitored by rheological and droplet size analysis.

  15. Size-exclusion chromatography of large molecules from coal liquids, petroleum residues, soots, biomass tars and humic substances.

    Science.gov (United States)

    Herod, Alan A; Zhuo, Yuqun; Kandiyoti, Rafael

    2003-06-30

    Size-exclusion chromatography (SEC) using 1-methyl-2-pyrrolidinone (NMP) as eluent has been calibrated using various standard polymers and model compounds and applied to the analysis of extracts of coal, petroleum and kerogens, to petroleum vacuum residues, soots, biomass tars and humic substances. Three separate columns of different molecular mass (MM) ranges were used, with detection by UV absorption; an evaporative light scattering detector was used for samples with no UV absorption. Fractionation was useful to separate signal from the less abundant high-mass material, which was normally masked by the strong signal from the more abundant low-mass material in the absence of fractionation. Fractionation methods used to isolate high-mass materials before SEC analysis included planar chromatography, column chromatography and solvent solubility. The apparently large molecules were concentrated into the fractions not soluble in common solvents and were relatively immobile in planar chromatography. All samples and fractions contained some material excluded from the column porosity. Evidence from other techniques suggests that the excluded material is of different structures from that of the resolved material rather than consisting of aggregates of small molecules. We speculate that the excluded material may elute early because the structures of this material are three-dimensional rather than planar or near planar.

  16. How great white sharks nourish their embryos to a large size: evidence of lipid histotrophy in lamnoid shark reproduction.

    Science.gov (United States)

    Sato, Keiichi; Nakamura, Masaru; Tomita, Taketeru; Toda, Minoru; Miyamoto, Kei; Nozu, Ryo

    2016-09-15

    The great white shark (Carcharodon carcharias) exhibits viviparous and oophagous reproduction. A 4950 mm total length (TL) gravid female accidentally caught by fishermen in the Okinawa Prefecture, Southern Japan carried six embryos (543-624 mm TL, three in each uterus). Both uteri contained copious amounts of yellowish viscous uterine fluid (over 79.2 litres in the left uterus), nutrient eggs and broken egg cases. The embryos had yolk stomachs that had ruptured, the mean volume of which was approximately 197.9 ml. Embryos had about 20 rows of potentially functional teeth in the upper and lower jaws. Periodic acid Schiff (PAS)-positive substances were observed on the surface and in the cytoplasm of the epithelial cells, and large, secretory, OsO4-oxidized lipid droplets of various sizes were distributed on the surface of the villous string epithelium on the uterine wall. Histological examination of the uterine wall showed it to consist of villi, similar to the trophonemata of Dasyatidae rays, suggesting that the large amount of fluid found in the uterus of the white shark was likely required for embryo nutrition. We conclude that: (1) the lipid-rich fluid is secreted from the uterine epithelium only in early gestation before the onset of oophagy, (2) the embryos probably use the abundant uterine fluid and encased nutrient eggs for nutrition at this stage of their development, and (3) the uterine fluid is the major source of embryonic nutrition before oophagy onset. This is the first record of the lipid histotrophy of reproduction among all shark species.

  17. How great white sharks nourish their embryos to a large size: evidence of lipid histotrophy in lamnoid shark reproduction

    Directory of Open Access Journals (Sweden)

    Keiichi Sato

    2016-09-01

    Full Text Available The great white shark (Carcharodon carcharias exhibits viviparous and oophagous reproduction. A 4950 mm total length (TL gravid female accidentally caught by fishermen in the Okinawa Prefecture, Southern Japan carried six embryos (543-624 mm TL, three in each uterus. Both uteri contained copious amounts of yellowish viscous uterine fluid (over 79.2 litres in the left uterus, nutrient eggs and broken egg cases. The embryos had yolk stomachs that had ruptured, the mean volume of which was approximately 197.9 ml. Embryos had about 20 rows of potentially functional teeth in the upper and lower jaws. Periodic acid Schiff (PAS-positive substances were observed on the surface and in the cytoplasm of the epithelial cells, and large, secretory, OsO4-oxidized lipid droplets of various sizes were distributed on the surface of the villous string epithelium on the uterine wall. Histological examination of the uterine wall showed it to consist of villi, similar to the trophonemata of Dasyatidae rays, suggesting that the large amount of fluid found in the uterus of the white shark was likely required for embryo nutrition. We conclude that: (1 the lipid-rich fluid is secreted from the uterine epithelium only in early gestation before the onset of oophagy, (2 the embryos probably use the abundant uterine fluid and encased nutrient eggs for nutrition at this stage of their development, and (3 the uterine fluid is the major source of embryonic nutrition before oophagy onset. This is the first record of the lipid histotrophy of reproduction among all shark species.

  18. INNOVATIVE TECHNIQUES AND TECHNOLOGY APPLICATION IN MANAGEMENT OF REMOTE HANDLED AND LARGE SIZED MIXED WASTE FORMS

    Energy Technology Data Exchange (ETDEWEB)

    BLACKFORD LT

    2008-02-04

    CH2M HILL Hanford Group, Inc. (CH2M HILL) plays a critical role in Hanford Site cleanup for the U. S. Department of Energy, Office of River Protection (ORP). CH2M HILL is responsible for the management of 177 tanks containing 53 million gallons of highly radioactive wastes generated from weapons production activities from 1943 through 1990. In that time, 149 single-shell tanks, ranging in capacity from 50,000 gallons to 500,000 gallons, and 28 double-shell tanks with a capacity of 1 million gallons each, were constructed and filled with toxic liquid wastes and sludges. The cleanup mission includes removing these radioactive waste solids from the single-shell tanks to double-shell tanks for staging as feed to the Waste Treatment Plant (WTP) on the Hanford Site for vitrification of the wastes and disposal on the Hanford Site and Yucca Mountain repository. Concentrated efforts in retrieving residual solid and sludges from the single-shell tanks began in 2003; the first tank retrieved was C-106 in the 200 East Area of the site. The process for retrieval requires installation of modified sluicing systems, vacuum systems, and pumping systems into existing tank risers. Inherent with this process is the removal of existing pumps, thermo-couples, and agitating and monitoring equipment from the tank to be retrieved. Historically, these types of equipment have been extremely difficult to manage from the aspect of radiological dose, size, and weight of the equipment, as well as their attendant operating and support systems such as electrical distribution and control panels, filter systems, and mobile retrieval systems. Significant effort and expense were required to manage this new waste stream and resulted in several events over time that were both determined to be unsafe for workers and potentially unsound for protection of the environment. Over the last four years, processes and systems have been developed that reduce worker exposures to these hazards, eliminate violations

  19. The welfare implications of large litter size in the domestic pig II: management factors

    DEFF Research Database (Denmark)

    Baxter, E.M.; Rutherford, K.M.D.; D'Eath, R.B.

    2013-01-01

    Increasing litter size has long been a goal of pig (Sus scrofa domesticus) breeders and producers in many countries. Whilst this has economic and environmental benefits for the pig industry, there are also implications for pig welfare. Certain management interventions are used when litter size ro...

  20. Full Scale Measurements of the Hydro-Elastic Response of Large Container Ships for Decision Support

    DEFF Research Database (Denmark)

    Andersen, Ingrid Marie Vincent

    and slender bow and stern sections) and their normal cargo loading condition, container ships are typically operated in a still-water hogging condition (tension in deck and compression in the bottom structure). The wave-induced bending moment is added to the still-water bending moment, which, together...... ships with focus on the assessment of the influence of the wave-induced high-frequency hull girder vibrations. In several cases, the high-frequency contribution to the fatigue damage is dominating the estimated fatigue damage. Spectral formulations for estimating fatigue damage from bi-modal processes...... with the smaller design hogging bending moment, generally makes the wave-induced hogging bending moment more critical than the sagging bending moment in the operation of container ships. As container ships of today become larger, their natural vibration frequencies become lower and approach the typical encounter...

  1. Fast Generation of Near-Optimal Plans for Eco-Efficient Stowage of Large Container Vessels

    DEFF Research Database (Denmark)

    Pacino, Dario; Delgado, Alberto; Jensen, Rune Møller

    2011-01-01

    Eco-efficient stowage plans that are both competitive and sustainable have become a priority for the shipping industry. Stowage planning is NP-hard and is a challenging optimization problem in practice. We propose a new 2-phase approach that generates near-optimal stowage plans and fulfills indus...... industrial time and quality requirements. Our approach combines an integer programming model for assigning groups of containers to storage areas of the vessel over multiple ports, and a constraint programming and local search procedure for stowing individual containers....

  2. Fast Generation of Near-Optimal Plans for Eco-Efficient Stowage of Large Container Vessels

    DEFF Research Database (Denmark)

    Pacino, Dario; Jensen, Rune Møller; Delgado-Ortegon, Alberto

    2011-01-01

    Eco-Efficient stowage plans that are both competitive and sustainable have become a priority for the shipping industry. Stowage planning is NP-hard and is a challenging optimization problem in practice. We propose a new 2-phase approach that generates near-optimal stowage plans and fulfills indus...... industrial time and quality requirements. Our approach combines an integer programming model for assigning groups of containers to storage areas of the vessel over multiple ports, and a constraint programming and local search procedure for stowing individual containers....

  3. Ventilation in medium-sized and large boiler houses; Ventilation i medelstora och stoerre pannhus

    Energy Technology Data Exchange (ETDEWEB)

    Grotherus, Dan [AaF Installation AB, Oerebro (Sweden); Larsson, Tord [Oerebro Univ. (Sweden). Dept. of Technology

    2005-04-01

    The purpose of this report is to exemplify and clarify the need for ventilation in medium-sized and large boiler houses. We will furthermore present some recommendations, guidelines and advice for the design and construction of a boiler house ventilation system to the plant owners and suppliers of equipment. Boiler house ventilation can be performed in different ways using mechanical or natural ventilation. The solution to be chosen depends on the following factors: Working environment requirements and a necessity to control temperature and pressure in the boiler house; The design of the boiler plant and house; The need for combustion air; The investment expenditure as well as operation and maintenance costs. Mechanical ventilation should be chosen if the aim is a controllable 'climate'. The mechanical ventilation can be either centrally situated or distributed with many aggregates in the boiler house. Centrally situated ventilation equipment will give a higher accessibility and lower maintenance costs than a distributed ventilation system. If the boiler house is designed with natural ventilation the air and flue gas fans will be the only ones installed. In this case temperature and pressure inside the boiler house will be difficult to control. The design factor for the ventilation plant in a boiler house is in most cases the demand to cool the air inside the boiler house to approximately 45 deg C. This is the highest temperature allowed by the Occupational Safety and Health Act in a work environment where the boiler operator is working alone. The air flow which is required for the combustion is normally less than the air flow needed to cool the air in the boiler house. The supply air which is cooling the air inside the boiler house should be supplied on several different levels to attain an efficient cooling. If the combustion air is taken from the heated indoor air the boiler house will work as a heat reclaimer. The difference between outdoor and indoor

  4. Stability assessment of injectable castor oil-based nano-sized emulsion containing cationic droplets stabilized by poloxamer-chitosan emulsifier films.

    Science.gov (United States)

    Tamilvanan, S; Kumar, B Ajith; Senthilkumar, S R; Baskar, Raj; Sekharan, T Raja

    2010-06-01

    The objectives of the present work were to prepare castor oil-based nano-sized emulsion containing cationic droplets stabilized by poloxamer-chitosan emulgator film and to assess the kinetic stability of the prepared cationic emulsion after subjecting it to thermal processing and freeze-thaw cycling. Presence of cryoprotectants (5%, w/w, sucrose +5%, w/w, sorbitol) improved the stability of emulsions to droplet aggregation during freeze-thaw cycling. After storing the emulsion at 4 degrees C, 25 degrees C, and 37 degrees C over a period of up to 6 months, no significant change was noted in mean diameter of the dispersed oil droplets. However, the emulsion stored at the highest temperature did show a progressive decrease in the pH and zeta potential values, whereas the emulsion kept at the lowest temperatures did not. This indicates that at 37 degrees C, free fatty acids were formed from the castor oil, and consequently, the liberated free fatty acids were responsible for the reduction in the emulsion pH and zeta potential values. Thus, the injectable castor oil-based nano-sized emulsion could be useful for incorporating various active pharmaceutical ingredients that are in size from small molecular drugs to large macromolecules such as oligonucleotides.

  5. Development of new mineral oil-based antifoams containing size-controlled hydrophobic silica particles for gloss paints.

    Science.gov (United States)

    Jo, Kiyokazu; Ishizuka, Motoyoshi; Shimabayashi, Katsuomi; Ando, Tsuyoshi

    2014-01-01

    Water-based architectural paints commonly contain either mineral oil-based or silicone-based antifoams. Mineral oil-based antifoams generally reduce the gloss of paint films; thus, silicone-based antifoams are mainly used in the field of architectural paints. The relationship between the antifoaming performance and the particle size of hydrophobic silica for mineral oil-based antifoams was investigated and a novel mineral oil-based antifoam that provided a glossy surface to the paint films equivalent to the surface obtained with silicone-based antifoams and with excellent antifoaming performance compared to silicone-based antifoams was developed. The novel mineral oil-based antifoam exhibits better performance than silicon-based antifoam, and thus the former is a perfect alternative to the latter for use in architectural paints.

  6. Investigating Transfer of Large Chromosomal Regions Containing the Pathogenicity Locus Between Clostridium difficile Strains

    NARCIS (Netherlands)

    Brouwer, Mike; Mullany, P.; Allan, E.; Roberts, P.

    2016-01-01

    The genomes of all sequenced Clostridium difficile isolates contain multiple mobile genetic elements. The chromosomally located pathogenicity locus (PaLoc), encoding the cytotoxins TcdA and TcdB, was previously hypothesized to be a mobile genetic element; however, mobility was not demonstrated. Here

  7. Investigating Transfer of Large Chromosomal Regions Containing the Pathogenicity Locus Between Clostridium difficile Strains

    NARCIS (Netherlands)

    Brouwer, Mike; Mullany, P.; Allan, E.; Roberts, P.

    2016-01-01

    The genomes of all sequenced Clostridium difficile isolates contain multiple mobile genetic elements. The chromosomally located pathogenicity locus (PaLoc), encoding the cytotoxins TcdA and TcdB, was previously hypothesized to be a mobile genetic element; however, mobility was not demonstrated. Here

  8. The temperature and size distribution of large water clusters from a non-equilibrium model

    Energy Technology Data Exchange (ETDEWEB)

    Gimelshein, N. [Gimel, Inc., San Jose, California 95124 (United States); Gimelshein, S., E-mail: gimelshe@usc.edu [University of Southern California, Los Angeles, California 90089 (United States); Pradzynski, C. C.; Zeuch, T., E-mail: tzeuch1@gwdg.de [Institut für Physikalische Chemie, Universität Göttingen, Tammanstr. 6, D-37077 Göttingen (Germany); Buck, U., E-mail: ubuck@gwdg.de [Max-Planck-Institut für Dynamik und Selbstorganisation, Am Faßberg 17, D-37077 Göttingen (Germany)

    2015-06-28

    A hybrid Lagrangian-Eulerian approach is used to examine the properties of water clusters formed in neon-water vapor mixtures expanding through microscale conical nozzles. Experimental size distributions were reliably determined by the sodium doping technique in a molecular beam machine. The comparison of computed size distributions and experimental data shows satisfactory agreement, especially for (H{sub 2}O){sub n} clusters with n larger than 50. Thus validated simulations provide size selected cluster temperature profiles in and outside the nozzle. This information is used for an in-depth analysis of the crystallization and water cluster aggregation dynamics of recently reported supersonic jet expansion experiments.

  9. Toward an understanding of the turbidity measurement of heterocoagulation rate constants of dispersions containing particles of different sizes.

    Science.gov (United States)

    Liu, Jie; Xu, Shenghua; Sun, Zhiwei

    2007-11-01

    Our previous studies have shown that the determination of coagulation rate constants by turbidity measurement becomes impossible for a certain operating wavelength (that is, its blind point) because at this wavelength the change in the turbidity of a dispersion completely loses its response to the coagulation process. Therefore, performing the turbidity measurement in the wavelength range near the blind point should be avoided. In this article, we demonstrate that the turbidity measurement of the rate constant for coagulation of a binary dispersion containing particles of two different sizes (heterocoagulation) presents special difficulties because the blind point shifts with not only particle size but also with the component fraction. Some important aspects of the turbidity measurement for the heterocoagulation rate constant are discussed and experimentally tested. It is emphasized that the T-matrix method can be used to correctly evaluate extinction cross sections of doublets formed during the heterocoagulation process, which is the key data determining the rate constant from the turbidity measurement, and choosing the appropriate operating wavelength and component fraction are important to achieving a more accurate rate constant. Finally, a simple scheme in experimentally determining the sensitivity of the turbidity changes with coagulation over a wavelength range is proposed.

  10. Small plants, large plants: the importance of plant size for the physiological ecology of vascular epiphytes.

    Science.gov (United States)

    Zotz, G; Hietz, P; Schmidt, G

    2001-10-01

    Recently, a number of publications have reported that many physiological properties of vascular epiphytes are a function of plant size. This short review will summarize what is known to date about this phenomenon, describe the possible mechanism and will discuss the consequences for the present understanding of epiphyte biology. Size-related changes are also known from other plant groups and it is argued that close attention should be paid to the size of the organisms under study in order to understand the performance and survival of a species in the field. In the light of these findings, the results of many earlier studies on epiphyte ecophysiology are now difficult to interpret because essential information on the size of the specimens used is missing.

  11. Enhanced Pixel-Driving Circuits for Active-Matrix Organic-Light-Emitting Diode Displays with Large Sizes

    Science.gov (United States)

    Yu, Sang Ho; Choi, Sung Wook; Shin, Hong Jae; Kwack, Kae Dal; Kim, Tae Whan

    2005-03-01

    Enhanced pixel-driving circuits for active-matrix organic-light-emitting diode (AM-OLED) displays with large sizes and highly uniform brightnesses were designed for system on panel. The driving method used the pre-charge functions of the data for a highly uniform brightness during a short time to program the current. The currents of the designed pixel-driving circuits were not significantly affected by variations in the threshold voltages, or by the mobilities of the driving thin-film transistors. These results indicate that the proposed pixel-driving circuits hold promise for potential applications in AM-OLED displays with large sizes and highly uniform brightnesses.

  12. Illusions of having small or large invisible bodies influence visual perception of object size

    OpenAIRE

    Björn van der Hoort; H Henrik Ehrsson

    2016-01-01

    The size of our body influences the perceived size of the world so that objects appear larger to children than to adults. The mechanisms underlying this effect remain unclear. It has been difficult to dissociate visual rescaling of the external environment based on an individual’s visible body from visual rescaling based on a central multisensory body representation. To differentiate these potential causal mechanisms, we manipulated body representation without a visible body by taking advanta...

  13. [Transport of large organic ions through syringomycin channels in the membranes containing dipole modifiers].

    Science.gov (United States)

    Efimova, S S; Ostroumova, O S; Malev, V V; Shchagina, L V

    2011-01-01

    The effect of the membrane dipole potential (Phid) on a conductance and a steady-state number of functioning channels formed by cyclic lipodepsipeptide syringomycin E (SRE) in bilayer lipid membranes made from phosphocholine and bathed in 0.4 M solution of sodium salts of aspartate, gluconate and chloride was shown. The magnitude of Phid was varied with the introduction to membrane bathing solutions of phloretin, which reduces the Phid, and RH 421, increasing the Phid. It was established that in all studied systems the increase in the membrane dipole potential cause a decrease in the steady-state number of open channels. In the systems containing sodium salts of aspartate (Asp) or gluconate (Glc), changes in the number of functioning channels are in an order of magnitude smaller than in systems containing sodium chloride. At the same time, the conductance (g) of single SRE-channels on the membranes bathed in NaCI solution increases with the increase in Phid, and in the systems containing NaAsp or NaGlc the conductance of single channels does not depend on the Phid. The latter is due to the lack of cation/anion selectivity of the SRE-channels in these systems. The different channel-forming activity of SRE in the experimental systems is defined by the gating charge of the channel and the partition coefficient of the dipole modifiers between the lipid and aqueous phases.

  14. Prey size and availability limits maximum size of rainbow trout in a large tailwater: insights from a drift-foraging bioenergetics model

    Science.gov (United States)

    Dodrill, Michael J.; Yackulic, Charles B.; Kennedy, Theodore A.; Haye, John W

    2016-01-01

    The cold and clear water conditions present below many large dams create ideal conditions for the development of economically important salmonid fisheries. Many of these tailwater fisheries have experienced declines in the abundance and condition of large trout species, yet the causes of these declines remain uncertain. Here, we develop, assess, and apply a drift-foraging bioenergetics model to identify the factors limiting rainbow trout (Oncorhynchus mykiss) growth in a large tailwater. We explored the relative importance of temperature, prey quantity, and prey size by constructing scenarios where these variables, both singly and in combination, were altered. Predicted growth matched empirical mass-at-age estimates, particularly for younger ages, demonstrating that the model accurately describes how current temperature and prey conditions interact to determine rainbow trout growth. Modeling scenarios that artificially inflated prey size and abundance demonstrate that rainbow trout growth is limited by the scarcity of large prey items and overall prey availability. For example, shifting 10% of the prey biomass to the 13 mm (large) length class, without increasing overall prey biomass, increased lifetime maximum mass of rainbow trout by 88%. Additionally, warmer temperatures resulted in lower predicted growth at current and lower levels of prey availability; however, growth was similar across all temperatures at higher levels of prey availability. Climate change will likely alter flow and temperature regimes in large rivers with corresponding changes to invertebrate prey resources used by fish. Broader application of drift-foraging bioenergetics models to build a mechanistic understanding of how changes to habitat conditions and prey resources affect growth of salmonids will benefit management of tailwater fisheries.

  15. Finite Size Corrections to the Large Deviation Function of the Density in the One Dimensional Symmetric Simple Exclusion Process

    Science.gov (United States)

    Derrida, Bernard; Retaux, Martin

    2013-09-01

    The symmetric simple exclusion process is one of the simplest out-of-equilibrium systems for which the steady state is known. Its large deviation functional of the density has been computed in the past both by microscopic and macroscopic approaches. Here we obtain the leading finite size correction to this large deviation functional. The result is compared to the similar corrections for equilibrium systems.

  16. CYCLES CONTAINING MANY VERTICES OFSUBSETS IN GRAPHS WITH LARGE DEGREE SUMS AND NEIGHBORHOOD UNIONS

    Institute of Scientific and Technical Information of China (English)

    LI Jianping

    2000-01-01

    Let G be a graph of order n and X V(G). G is called X-cyclable if Ghas an X-cycle, i.e., a cycle containing all vertices of X. Define the parameters α(X) =max{| S|| S is an independent vertex set in G[X] induced by X}, σk (X) = min{Σki=1 dG (xi)|{x1, x2,…, xk} is an independent vertex set in G[X]} and NCk(X)= min{|ki=1NG(x2)|| {x1,x2,… ,xk} is an independent vertex set in G[X] }. Our main result is as follows: If G is a 1-tough graph and X V(G) with σ3(X) ≥ n, then for every integer t ≥ 1, G has a cycle C containing at least min{|X|, 1/2(2|X|- n + 3δ(X) + 1 - t), |X| + NCt(X) - α(X)}vertices of X, where δ(X) = [1/3σ3(X)]. This result further extends previous results in H.J.Broersma et al. in terms of X-cyclability. We also obtain that if G is a 1-tough graph with σ3(X) ≥ n, then for every integer t ≥ 1, G has a cycle containing at least min{|X|, 1/3(4|X|-2n + 4δ(X) + 1 - 2t), NC t (X) + NCt (X) } vertices of X, where NC t (X) = min{ |N (I) ∩ X || I is an independent set of t vertices of X}. Analogous results are established for 2-connected graphs.

  17. Multilayered sandwich-like architecture containing large-scale faceted Al–Cu–Fe quasicrystal grains

    Energy Technology Data Exchange (ETDEWEB)

    Wei, Dongxia; He, Zhanbing, E-mail: hezhanbing@ustb.edu.cn

    2016-01-15

    Faceted quasicrystals are structurally special compared with traditional crystals. Although the application of faceted quasicrystals has been expected, wide-scale application has not occurred owing to the limited exposure of the facets. Using a facile method of heat treatment, we synthesize a multilayered sandwich-like structure with each layer composed of large-scale pentagonal-dodecahedra of Al–Cu–Fe quasicrystals. Moreover, there are channels between the adjacent Al–Cu–Fe layers that serve to increase the exposure of the facets of quasicrystals. Scanning electron microscopy, transmission electron microscopy, and X-ray diffraction are used to characterize the multilayered architecture, and the generation mechanisms of this special structure are also discussed. - Highlights: • A multilayered sandwich-like structure is produced by a facile method. • Each layer is covered by large-scale faceted Al–Cu–Fe quasicrystals. • There are channels between the adjacent Al–Cu–Fe layers.

  18. Impedance Eduction in Large Ducts Containing Higher-Order Modes and Grazing Flow

    Science.gov (United States)

    Watson, Willie R.; Jones, Michael G.

    2017-01-01

    Impedance eduction test data are acquired in ducts with small and large cross-sectional areas at the NASA Langley Research Center. An improved data acquisition system in the large duct has resulted in increased control of the acoustic energy in source modes and more accurate resolution of higher-order duct modes compared to previous tests. Two impedance eduction methods that take advantage of the improved data acquisition to educe the liner impedance in grazing flow are presented. One method measures the axial propagation constant of a dominant mode in the liner test section (by implementing the Kumarsean and Tufts algorithm) and educes the impedance from an exact analytical expression. The second method solves numerically the convected Helmholtz equation and minimizes an objective function to obtain the liner impedance. The two methods are tested first on data synthesized from an exact mode solution and then on measured data. Results show that when the methods are applied to data acquired in the larger duct with a dominant higher-order mode, the same impedance spectra are educed as that obtained in the small duct where only the plane wave mode propagates. This result holds for each higher-order mode in the large duct provided that the higher-order mode is sufficiently attenuated by the liner.

  19. Influence of phantom size on output, peak scatter factor, and percentage depth dose in large-field photon irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Podgorsak, E.B.; Pla, C.; Evans, M.D.C.; Pla, M.

    1985-09-01

    Machine outputs, peak scatter factors, and central axis percentage depth dose distributions were measured for various phantom sizes in large radiation fields produced at extended distances by cobalt, 6-MV, and 10-MV photon beams. The results can be applied to practical total body irradiation procedures which usually involve treatment volumes smaller than the actual field sizes in order to provide a uniform total body exposure to radiation. Our study addresses the question of the appropriate phantom dimension to be used in the calibration of photon beams employed in total body irradiations. The measurements show that the machine outputs are only slightly dependent on phantom size; the percentage depth dose distributions, however, are strongly dependent on the phantom size, suggesting that machine data for total body irradiations should be measured in phantoms whose dimensions approximate the patient during the total body irradiation. Peak scatter factors measured in large-field/small-phantom configurations link up well with the published small-field/large-phantom data. The finite patient thickness lowers the dose to points close to the beam exit surface by a few percent, when compared to dose measured at the same depths in infinitely thick phantoms. The surface doses in large radiation fields are essentially independent of phantom cross sections and range from 40% for the 10-MV beam, to 65% for the 6-MV beam and 80% for the cobalt beam.

  20. 78 FR 32865 - Procedures To Establish Appropriate Minimum Block Sizes for Large Notional Off-Facility Swaps and...

    Science.gov (United States)

    2013-05-31

    ... and Lasse Heje Pedersen, Predatory Trading, Journal of Finance LX 4, Aug. 2005, available at http... Notional Amount Calculation VIII. List of Commenters Who Responded to the Further Block Proposal I... Establish Appropriate Minimum Block Sizes for Large Notional Off-Facility Swaps and Block Trades, 77 FR...

  1. Perception of Business Studies Teachers on the Infuence of Large Class Size in Public Secondary Schools in Yobe State, Nigeria

    Science.gov (United States)

    Mamman, Jummai; Chadi, Aishatu Mohammad; Jirgi, Ibrahim

    2015-01-01

    This is a survey study conducted to determine the perception of business studies teacher's on the influence of large class size in Yobe state public secondary school. Three research questions were raised to guide the study. The population comprised of one hundred and twenty (120) business studies teachers from one hundred and five (105) Secondary…

  2. Short-term pressure and temperature MSLB response analyses for large dry containment of the Maanshan nuclear power station

    Energy Technology Data Exchange (ETDEWEB)

    Dai, Liang-Che, E-mail: lcdai@iner.gov.tw; Chen, Yen-Shu; Yuann, Yng-Ruey

    2014-12-15

    Highlights: • The GOTHIC code is used for the PWR dry containment pressure and temperature analysis. • Boundary conditions are hot standby and 102% power main steam line break accidents. • Containment pressure and temperature responses of GOTHIC are similar with FSAR. • The capability of the developed model to perform licensing calculation is assessed. - Abstract: Units 1 and 2 of the Maanshan nuclear power station are the typical Westinghouse three-loop PWR (pressurized water reactor) with large dry containments. In this study, the containment analysis program GOTHIC is adopted for the dry containment pressure and temperature analysis. Free air space and sump of the PWR dry containment are individually modeled as control volumes. The containment spray system and fan cooler unit are also considered in the GOTHIC model. The blowdown mass and energy data of the main steam line break (hot standby condition and various reactor thermal power levels) are tabulated in the Maanshan Final Safety Analysis Report (FSAR) 6.2 which could be used as the boundary conditions for the containment model. The calculated containment pressure and temperature behaviors of the selected cases are in good agreement with the FSAR results. In this study, hot standby and 102% reactor thermal power main steam line break accidents are selected. The calculated peak containment pressure is 323.50 kPag (46.92 psig) for hot standby MSLB, which is a little higher than the FSAR value of 311.92 kPag (45.24 psig). But it is still below the design value of 413.69 kPag (60 psig). The calculated peak vapor temperature inside the containment is 187.0 °C (368.59 F) for 102% reactor thermal power MSLB, which is lower than the FSAR result of 194.42 °C (381.95 F). The effects of the containment spray system and fan cooler units could be clearly observed in the GOTHIC analysis. The calculated containment pressure and temperature behaviors of the selected cases are in good agreement with the FSAR

  3. Large group size yields group stability in the cooperatively breeding cichlid Neolamprologus pulcher

    NARCIS (Netherlands)

    Heg, D; Bachar, Z; Taborsky, M

    2005-01-01

    Group size has been shown to positively influence survival of group members in many cooperatively breeding vertebrates, including the Lake Tanganyika cichlid Neolamprologus pulcher, suggesting Allee effects. However, long-term data are scarce to test how these survival differences translate into cha

  4. Occupational lifting during pregnancy and child's birth size in a large cohort study

    DEFF Research Database (Denmark)

    Juhl, Mette; Larsen, Pernille Stemann; Andersen, Per Kragh

    2014-01-01

    OBJECTIVES: It has been suggested that the handling of heavy loads during pregnancy is associated with impaired fetal growth. We examined the association between quantity and frequency of maternal occupational lifting and the child's size at birth, measured by weight, length, ponderal index, small...

  5. Implementation of Exhaust Gas Recirculation for Double Stage Waste Heat Recovery System on Large Container Vessel

    DEFF Research Database (Denmark)

    Andreasen, Morten; Marissal, Matthieu; Sørensen, Kim;

    2014-01-01

    of recovering some of the waste heat from the exhaust gas. This heat is converted into electrical energy used on-board instead of using auxiliary engines. Exhaust Gas Recirculation (EGR) systems, are recirculating a part of the exhaust gas through the engine combustion chamber to reduce emissions. WHRS combined......Concerned to push ships to have a lower impact on the environment, the International Maritime Organization are implementing stricter regulation of NOx and SOx emissions, called Tier III, within emission control areas (ECAs). Waste Heat Recovery Systems (WHRS) on container ships consist...... with EGR is a potential way to improve system efficiency while reducing emissions. This paper investigates the feasibility of combining the two systems. EGR dilutes the fuel, lowering the combustion temperature and thereby the formation of NOx, to reach Tier III limitation. A double stage WHRS is set up...

  6. Job Stress in the United Kingdom: Are Small and Medium-Sized Enterprises and Large Enterprises Different?

    Science.gov (United States)

    Lai, Yanqing; Saridakis, George; Blackburn, Robert

    2015-08-01

    This paper examines the relationships between firm size and employees' experience of work stress. We used a matched employer-employee dataset (Workplace Employment Relations Survey 2011) that comprises of 7182 employees from 1210 private organizations in the United Kingdom. Initially, we find that employees in small and medium-sized enterprises experience lower level of overall job stress than those in large enterprises, although the effect disappears when we control for individual and organizational characteristics in the model. We also find that quantitative work overload, job insecurity and poor promotion opportunities, good work relationships and poor communication are strongly associated with job stress in the small and medium-sized enterprises, whereas qualitative work overload, poor job autonomy and employee engagements are more related with larger enterprises. Hence, our estimates show that the association and magnitude of estimated effects differ significantly by enterprise size. Copyright © 2013 John Wiley & Sons, Ltd.

  7. Separation of large DNA molecules by size exclusion chromatography-based microchip with on-chip concentration structure

    Science.gov (United States)

    Azuma, Naoki; Itoh, Shintaro; Fukuzawa, Kenji; Zhang, Hedong

    2016-06-01

    The separation of DNA molecules according to their size represents a fundamental bioanalytical procedure. Here, we report the development of a chip-sized device, consisting of micrometer-sized fence structures fabricated in a microchannel, for the separation of large DNA molecules (over 10 kbp) based on the principle of size exclusion chromatography (SEC). In order to achieve separation, two approaches were utilized: first, the DNA samples were concentrated immediately prior to separation using nanoslit structures, with the aim of improving the resolution. Second, a theoretical model of SEC-based separation was established and applied in order to predict the optimal voltage range for separation. In this study, we achieved separation of λ DNA (48.5 kbp) and T4 DNA (166 kbp) using the present SEC-based microchip.

  8. Performance of Large Neutron Detectors Containing Lithium-Gadolinium-Borate Scintillator

    Energy Technology Data Exchange (ETDEWEB)

    Slaughter, David M.; Stuart, Cory R.; Klaass, R. Fred; Merrill, David B. [MSI/Photogenics Division, Orem, Utah (United States)

    2015-07-01

    This paper describes the development and testing of a neutron counter, spectrometer, and dosimeter that is compact, efficient, and accurate. A self-contained neutron detection instrument has wide applications in health physics, scientific research, and programs to detect, monitor, and control strategic nuclear materials (SNM). The 1.3 liter detector head for this instrument is a composite detector with an organic scintillator containing uniformly distributed {sup 6}Li{sub 6}{sup nat}Gd{sup 10}B{sub 3}O{sub 9}:Ce (LGB:Ce) microcrystals. The plastic scintillator acts to slow impinging neutrons and emits light proportional to the energy lost by the neutrons as they moderate in the detector body. Moderating neutrons that have slowed sufficiently capture in one of the Lithium-6, Boron-10, or Gadolinium-157 atoms in the LGB:Ce scintillator, which then releases the capture energy in a characteristic cerium emission pulse. The measured captured pulses indicate the presence of neutrons. When a scintillating fluor is present in the plastic, the light pulse resulting from the neutron moderating in the plastic is paired with the LGB:Ce capture pulse to identify the energy of the neutron. About 2% of the impinging neutrons lose all of their energy in a single collision with the detector. There is a linear relationship between the pulse areas of this group of neutrons and energy. The other 98% of neutrons have a wide range of collision histories within the detector body. When these neutrons are 'binned' into energy groups, each group contains a distribution of pulse areas. This data was used to assist in the unfolding of the neutron spectra. The unfolded spectra were then validated with known spectra, at both neutron emitting isotopes and fission/accelerator facilities. Having validated spectra, the dose equivalent and dose rate are determined by applying standard, regulatory damage coefficients to the measured neutron counts for each energy bin of the spectra. Testing

  9. The maximum sizes of large scale structures in alternative theories of gravity

    CERN Document Server

    Bhattacharya, Sourav; Romano, Antonio Enea; Skordis, Constantinos; Tomaras, Theodore N

    2016-01-01

    The maximum size of a cosmic structure is given by the maximum turnaround radius -- the scale where the attraction due to its mass is balanced by the repulsion due to dark energy. We derive generic formulas for the estimation of the maximum turnaround radius in any theory of gravity obeying the Einstein equivalence principle, in two situations: on a spherically symmetric spacetime and on a perturbed Friedman-Robertson-Walker spacetime. We show that the two formulas agree. As an application of our formula, we calculate the maximum turnaround radius in the case of the Brans-Dicke theory of gravity. We find that for this theory, such maximum sizes always lie above the $\\Lambda$CDM value, by a factor $1 + \\frac{1}{3\\omega}$, where $\\omega\\gg 1$ is the Brans-Dicke parameter, implying consistency of the theory with current data.

  10. Direct Solve of Electrically Large Integral Equations for Problem Sizes to 1M Unknowns

    Science.gov (United States)

    Shaeffer, John

    2008-01-01

    Matrix methods for solving integral equations via direct solve LU factorization are presently limited to weeks to months of very expensive supercomputer time for problems sizes of several hundred thousand unknowns. This report presents matrix LU factor solutions for electromagnetic scattering problems for problem sizes to one million unknowns with thousands of right hand sides that run in mere days on PC level hardware. This EM solution is accomplished by utilizing the numerical low rank nature of spatially blocked unknowns using the Adaptive Cross Approximation for compressing the rank deficient blocks of the system Z matrix, the L and U factors, the right hand side forcing function and the final current solution. This compressed matrix solution is applied to a frequency domain EM solution of Maxwell's equations using standard Method of Moments approach. Compressed matrix storage and operations count leads to orders of magnitude reduction in memory and run time.

  11. Optimization methodology for large scale fin geometry on the steel containment of a Public Acceptable Simple SMR (PASS)

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Do Yun, E-mail: dykim0129@kaist.ac.kr; NO, Hee Cheon, E-mail: hcno@kaist.ac.kr; Kim, Ho Sik, E-mail: hskim25@kaist.ac.kr

    2015-11-15

    Highlights: • Optimization methodology for fin geometry on the steel containment is established. • Optimum spacing is 7 cm in PASS containment. • Optimum thickness is 0.9–1.8 cm when a fin height is 10–25 cm. • Optimal fin geometry is determined in given fin height by overall effectiveness correlation. • 13% of material volume and 43% of containment volume are reduced by using fins. - Abstracts: Heat removal capability through a steel containment is important in accident situations to preserve the integrity of a nuclear power plant which adopts a steel containment concept. A heat transfer rate will be enhanced by using fins on the external surface of the steel containment. The fins, however, cause to increase flow resistance and to deteriorate the heat transfer rate at the same time. Therefore, this study investigates an optimization methodology of large scale fin geometry for a vertical base where a natural convection flow regime is turbulent. Rectangular plate fins adopted in the steel containment of a Public Acceptable Simple SMR (PASS) is used as a reference. The heat transfer rate through the fins is obtained from CFD tools. In order to optimize fin geometry, an overall effectiveness concept is introduced as a fin performance parameter. The optimizing procedure is starting from finding optimum spacing. Then, optimum thickness is calculated and finally optimal fin geometry is suggested. Scale analysis is conducted to show the existence of an optimum spacing which turns out to be 7 cm in case of PASS. Optimum thickness is obtained by the overall effectiveness correlation, which is derived from a total heat transfer coefficient correlation. The total heat transfer coefficient correlation of a vertical fin array is suggested considering both of natural convection and radiation. However, the optimum thickness is changed as a fin height varies. Therefore, optimal fin geometry is obtained as a function of a fin height. With the assumption that the heat

  12. Highly crystallized nanometer-sized zeolite a with large Cs adsorption capability for the decontamination of water.

    Science.gov (United States)

    Torad, Nagy L; Naito, Masanobu; Tatami, Junichi; Endo, Akira; Leo, Sin-Yen; Ishihara, Shinsuke; Wu, Kevin C-W; Wakihara, Toru; Yamauchi, Yusuke

    2014-03-01

    Nanometer-sized zeolite A with a large cesium (Cs) uptake capability is prepared through a simple post-milling recrystallization method. This method is suitable for producing nanometer-sized zeolite in large scale, as additional organic compounds are not needed to control zeolite nucleation and crystal growth. Herein, we perform a quartz crystal microbalance (QCM) study to evaluate the uptake ability of Cs ions by zeolite, to the best of our knowledge, for the first time. In comparison to micrometer-sized zeolite A, nanometer-sized zeolite A can rapidly accommodate a larger amount of Cs ions into the zeolite crystal structure, owing to its high external surface area. Nanometer-sized zeolite is a promising candidate for the removal of radioactive Cs ions from polluted water. Our QCM study on Cs adsorption uptake behavior provides the information of adsorption kinetics (e.g., adsorption amounts and rates). This technique is applicable to other zeolites, which will be highly valuable for further consideration of radioactive Cs removal in the future.

  13. Spatiotemporal Chaos in Large Systems The Scaling of Complexity with Size

    CERN Document Server

    Greenside, H S

    1996-01-01

    The dynamics of a nonequilibrium system can become complex because the system has many components (e.g., a human brain), because the system is strongly driven from equilibrium (e.g., large Reynolds-number flows), or because the system becomes large compared to certain intrinsic length scales. Recent experimental and theoretical work is reviewed that addresses this last route to complexity. In the idealized case of a sufficiently large, nontransient, homogeneous, and chaotic system, the fractal dimension D becomes proportional to the system's volume V which defines the regime of extensive chaos. The extensivity of the fractal dimension suggests a new way to characterize correlations in high-dimensional systems in terms of an intensive dimension correlation length $\\xi_\\delta$. Recent calculations at Duke University show that $\\xi_\\delta$ is a length scale smaller than and independent of some commonly used measures of disorder such as the two-point and mutual-information correlation lengths. Identifying the bas...

  14. Complete correction of hemophilia A with adeno-associated viral vectors containing a full-size expression cassette.

    Science.gov (United States)

    Lu, Hui; Chen, Lingxia; Wang, Jinhui; Huack, Bernd; Sarkar, Rita; Zhou, Shangzhen; Xu, Ray; Ding, Qiulan; Wang, Xuefeng; Wang, Hongli; Xiao, Weidong

    2008-06-01

    Hemophilia A is caused by a deficiency in the factor VIII (FVIII) gene. Constrained by limited packaging capacity, even the 4.3-kb B domain-deleted FVIII remained a challenge for delivery by a single adeno-associated viral (AAV) vector. Studies have shown that up to a 6.6-kb vector sequence may be packaged into AAV virions, which suggested an alternative strategy for hemophilia A gene therapy. To explore the usefulness of AAV vectors carrying an oversized FVIII gene, we constructed the AAV-FVIII vector under the control of a beta-actin promoter with a cytomegalovirus enhancer (CB) and a bovine growth hormone (bGH) poly(A) sequence. The CB promoter plus bGH signal was shown to be 3- to 5-fold more potent than the mini-transthyretin (TTR) promoter with a synthetic poly(A) sequence for directing FVIII expression in the liver. Despite the 5.75-kb genome size of pAAV-CB-FVIII, sufficient AAV vectors were produced for in vivo testing. Approximately 3- to 5-fold more FVIII secretion was observed in animals receiving AAV-CB-FVIII vectors than in those receiving standard-sized AAV-TTR-FVIII vectors. Both the activated partial thromboplastin time assay and the whole blood thromboelastographic analysis confirmed that AAV-FVIII vectors fully corrected the bleeding phenotype of hemophilia mice. These results suggest that AAV vectors with an oversized genome should be useful for not only hemophilia A gene therapy but also other diseases with large cDNA such as muscular dystrophy and cystic fibrosis.

  15. Large sample area and size are needed for forest soil seed bank studies to ensure low discrepancy with standing vegetation.

    Directory of Open Access Journals (Sweden)

    You-xin Shen

    Full Text Available A large number of small-sized samples invariably shows that woody species are absent from forest soil seed banks, leading to a large discrepancy with the seedling bank on the forest floor. We ask: 1 Does this conventional sampling strategy limit the detection of seeds of woody species? 2 Are large sample areas and sample sizes needed for higher recovery of seeds of woody species? We collected 100 samples that were 10 cm (length × 10 cm (width × 10 cm (depth, referred to as larger number of small-sized samples (LNSS in a 1 ha forest plot, and placed them to germinate in a greenhouse, and collected 30 samples that were 1 m × 1 m × 10 cm, referred to as small number of large-sized samples (SNLS and placed them (10 each in a nearby secondary forest, shrub land and grass land. Only 15.7% of woody plant species of the forest stand were detected by the 100 LNSS, contrasting with 22.9%, 37.3% and 20.5% woody plant species being detected by SNLS in the secondary forest, shrub land and grassland, respectively. The increased number of species vs. sampled areas confirmed power-law relationships for forest stand, the LNSS and SNLS at all three recipient sites. Our results, although based on one forest, indicate that conventional LNSS did not yield a high percentage of detection for woody species, but SNLS strategy yielded a higher percentage of detection for woody species in the seed bank if samples were exposed to a better field germination environment. A 4 m2 minimum sample area derived from power equations is larger than the sampled area in most studies in the literature. Increased sample size also is needed to obtain an increased sample area if the number of samples is to remain relatively low.

  16. Optimal Siting and Sizing of Energy Storage System for Power Systems with Large-scale Wind Power Integration

    DEFF Research Database (Denmark)

    Zhao, Haoran; Wu, Qiuwei; Huang, Shaojun

    2015-01-01

    This paper proposes algorithms for optimal sitingand sizing of Energy Storage System (ESS) for the operationplanning of power systems with large scale wind power integration.The ESS in this study aims to mitigate the wind powerfluctuations during the interval between two rolling Economic...... optimal siting and sizing of storage units throughoutthe network. These questions are investigated using an IEEE benchmark system......Dispatches (EDs) in order to maintain generation-load balance.The charging and discharging of ESS is optimized consideringoperation cost of conventional generators, capital cost of ESSand transmission losses. The statistics from simulated systemoperations are then coupled to the planning process to determinethe...

  17. Early outcome in renal transplantation from large donors to small and size-matched recipients - a porcine experimental model

    DEFF Research Database (Denmark)

    Ravlo, Kristian; Chhoden, Tashi; Søndergaard, Peter

    2012-01-01

    Kidney transplantation from a large donor to a small recipient, as in pediatric transplantation, is associated with an increased risk of thrombosis and DGF. We established a porcine model for renal transplantation from an adult donor to a small or size-matched recipient with a high risk of DGF...... and studied GFR, RPP using MRI, and markers of kidney injury within 10 h after transplantation. After induction of BD, kidneys were removed from ∼63-kg donors and kept in cold storage for ∼22 h until transplanted into small (∼15 kg, n = 8) or size-matched (n = 8) recipients. A reduction in GFR was observed...

  18. Innovative capabilities, firm performance and foreign ownership: Empirical analysis of large and medium-sized companies form all industries

    Directory of Open Access Journals (Sweden)

    Anita Talaja

    2013-10-01

    Full Text Available In this article innovative capability, i.e. the ability of new products and markets development, is analyzed and empirically tested. The results have proven that the companies with more developed innovative capabilities achieve higher performance levels, but that there is no difference in innovative capabilities between large and medium-sized companies. On the other hand, medium-sized companies have slightly higher levels of sales growth and increase in market share. Also, companies in foreign ownership are better at development of new products and new production methods, and they have higher levels of sales growth, market share and increase in market share.

  19. Long-term treatment of phenylketonuria with a new medical food containing large neutral amino acids

    Science.gov (United States)

    Concolino, D; Mascaro, I; Moricca, M T; Bonapace, G; Matalon, K; Trapasso, J; Radhakrishnan, G; Ferrara, C; Matalon, R; Strisciuglio, P

    2017-01-01

    Background/Objectives: Phenylketonuria (PKU) is an autosomal recessive disease caused by deficient activity of phenylalanine hydroxylase. A low phenylalanine (Phe) diet is used to treat PKU. The diet is very restrictive, and dietary adherence tends to decrease as patients get older. Methods to improve dietary adherence and blood Phe control are continuously under investigation. Subjects/Methods: A new formula Phe-neutral amino acid (PheLNAA) has been tested in this study with the purpose of improving the compliance and lowering blood phenylalanine. The formula has been tested for nitrogen balance, and it is nutritionally complete. It is fortified with more nutritional additives that can be deficient in the PKU diet, such as B12, Biotin, DHA, Lutein and increased levels of large neutral amino acids to help lower blood Phe. The new formula has been tested on 12 patients with a loading test of 4 weeks. Results: Fifty-eight percent of patients had a significant decline in blood Phe concentration from baseline throughout the study. The PheLNAA was well tolerated with excellent compliance and without illnesses during the study. Conclusions: In conclusion, the new formula is suitable for life-long treatment of PKU, and it offers the PKU clinic a new choice for treatment. PMID:27623981

  20. Small genomes and large seeds: chromosome numbers, genome size and seed mass in diploid Aesculus species (Sapindaceae).

    Science.gov (United States)

    Krahulcová, Anna; Trávnícek, Pavel; Krahulec, František; Rejmánek, Marcel

    2017-04-01

    Aesculus L. (horse chestnut, buckeye) is a genus of 12-19 extant woody species native to the temperate Northern Hemisphere. This genus is known for unusually large seeds among angiosperms. While chromosome counts are available for many Aesculus species, only one has had its genome size measured. The aim of this study is to provide more genome size data and analyse the relationship between genome size and seed mass in this genus. Chromosome numbers in root tip cuttings were confirmed for four species and reported for the first time for three additional species. Flow cytometric measurements of 2C nuclear DNA values were conducted on eight species, and mean seed mass values were estimated for the same taxa. The same chromosome number, 2 n = 40, was determined in all investigated taxa. Original measurements of 2C values for seven Aesculus species (eight taxa), added to just one reliable datum for A. hippocastanum , confirmed the notion that the genome size in this genus with relatively large seeds is surprisingly low, ranging from 0·955 pg 2C -1 in A. parviflora to 1·275 pg 2C -1 in A. glabra var. glabra. The chromosome number of 2 n = 40 seems to be conclusively the universal 2 n number for non-hybrid species in this genus. Aesculus genome sizes are relatively small, not only within its own family, Sapindaceae, but also within woody angiosperms. The genome sizes seem to be distinct and non-overlapping among the four major Aesculus clades. These results provide an extra support for the most recent reconstruction of Aesculus phylogeny. The correlation between the 2C values and seed masses in examined Aesculus species is slightly negative and not significant. However, when the four major clades are treated separately, there is consistent positive association between larger genome size and larger seed mass within individual lineages.

  1. A hybrid adaptive large neighborhood search algorithm applied to a lot-sizing problem

    DEFF Research Database (Denmark)

    Muller, Laurent Flindt; Spoorendonk, Simon

    This paper presents a hybrid of a general heuristic framework that has been successfully applied to vehicle routing problems and a general purpose MIP solver. The framework uses local search and an adaptive procedure which choses between a set of large neighborhoods to be searched. A mixed integer...

  2. Magnetomotive forming for precision sizing and joining of large-diameter tubes

    Science.gov (United States)

    Bennight, J. D.; Schwinghamer, R. J.

    1969-01-01

    Portable electromagnetic coil enables high precision expansion or constriction and joining of large diameter metal tubes. A nonconducting mandrel or forming die is used on the side of the tubes wall opposite the coil. The coil is insulated from the tube by a thin plastic sleeve.

  3. Participation and Collaborative Learning in Large Class Sizes: Wiki, Can You Help Me?

    Science.gov (United States)

    de Arriba, Raúl

    2017-01-01

    Collaborative learning has a long tradition within higher education. However, its application in classes with a large number of students is complicated, since it is a teaching method that requires a high level of participation from the students and careful monitoring of the process by the educator. This article presents an experience in…

  4. NiMo/Al2O3 catalyst containing nano-sized zeolite Y for deep hydrodesulfurization and hydrodenitrogenation of diesel

    Institute of Scientific and Technical Information of China (English)

    Hailiang Yin; Tongna Zhou; Yunqi Liu; Yongming Chai; Chenguang Liu

    2011-01-01

    Two mixed-matrix NiMo/Al2O3 catalysts containing nano- and micro-sized zeolite Y have been prepared to explore the size effect of zeolite Y particle on the hydrodesulfurization (HDS) and hydrodenitrogenation (HDN) activities of fluid catalytic cracking (FCC) diesel.They were characterized by SEM,BET,XRD,H2-TPR,NH3-TPD and HRTEM.The results show that the catalyst containing nano-sized zeolite Y possesses larger average pore diameter,higher pore volume,weaker and lesser acid sites,more easily reducible metal phases,shorter MoS2 slabs and more slab layers than the catalyst containing micro-sized zeolite Y.The catalysts were also evaluated with a high-pressure fixed-bed reactor using real FCC diesel as feed.The results display that the catalyst containing nano-sized zeolite Y bears higher HDS and HDN activities and exhibits higher relative rate constant for the removal of total sulfur or nitrogen than the one containing micro-sized zeolite.

  5. Preventing large birth size in women with preexisting diabetes mellitus: The benefit of appropriate gestational weight gain

    Science.gov (United States)

    Kim, Shin Y.; Sharma, Andrea J.; Sappenfield, William; Salihu, Hamisu M.

    2016-01-01

    Objective To estimate the percentage of infants with large birth size attributable to excess gestational weight gain (GWG), independent of prepregnancy body mass index, among mothers with preexisting diabetes mellitus (PDM). Study design We analyzed 2004–2008 Florida linked birth certificate and maternal hospital discharge data of live, term (37–41 weeks) singleton deliveries (N = 641,857). We calculated prevalence of large-for-gestational age (LGA) (birth weight-for-gestational age ≥ 90th percentile) and macrosomia (birth weight > 4500 g) by GWG categories (inadequate, appropriate, or excess). We used multivariable logistic regression to estimate the relative risk (RR) of large birth size associated with excess compared to appropriate GWG among mothers with PDM. We then estimated the population attributable fraction (PAF) of large birth size due to excess GWG among mothers with PDM (n = 4427). Results Regardless of diabetes status, half of mothers (51.2%) gained weight in excess of recommendations. Large birth size was higher in infants of mothers with PDM than in infants of mothers without diabetes (28.8% versus 9.4% for LGA, 5.8% versus 0.9% for macrosomia). Among women with PDM, the adjusted RR of having an LGA infant was 1.7 (95% CI 1.5, 1.9) for women with excess GWG compared to those with appropriate gain; the PAF was 27.7% (95% CI 22.0, 33.3). For macrosomia, the adjusted RR associated with excess GWG was 2.1 (95% CI 1.5, 2.9) and the PAF was 38.6% (95% CI 24.9, 52.4). Conclusion Preventing excess GWG may avert over one-third of macrosomic term infants of mothers with PDM. Effective strategies to prevent excess GWG are needed. PMID:27539071

  6. Mapping trends of large and medium size carnivores of conservation interest in Romania

    Directory of Open Access Journals (Sweden)

    Mihai Cristian Adamescu

    2014-07-01

    Full Text Available We analysed yearly estimates of population size data during 2001-2012 for five carnivores species of conservation interest (Ursus arctos, Canis lupus, Lynx lynx, Felis silvestris and Canis aureus. Population size estimations were done by the game management authorities and integrated by the competent authorities on the Ministry of Environment and Climate Change. Trends in data were detected using non-parametric Mann-Kendall test. This test was chosen considering the short length of data series and its usefulness for non-normal distributed data. The trend was tested at three spatial scales: game management units (n=1565, biogeographical region (n=5 and national. Trends depicted for each game management unit were plotted using ArcGIS, resulting species trend distribution maps. For the studied period increasing population trends were observed for Ursus arctos, Canis lupus, Canis aureus and Lynx lynx, while for Felis silvestris there was no trend recorded. Such an analysis in especially useful for conservation proposes, game management and reporting obligations under article 17 of the EC Habitat Directive, using population trend as a proxy for population dynamics. We conclude that the status of the five carnivore species is favourable during the study period.

  7. Large-size message construction for ETI: Inductive self-interpretation in LINCOS

    Science.gov (United States)

    Ollongren, Alexander

    2011-02-01

    Ingredients of the author's Lingua Cosmica for communication with extra-terrestrial intelligent beings are examined with self-interpretation in mind. The most important ingredients for that purpose are inductive definitions. These definitions contain ordered sequences of induction hypotheses, identified by mutually distinctive constructors. If an assertion involving an inductive definition is to be verified, all induction hypotheses must be taken into account, i.e. they must be eliminated one by one. The implementation of the elimination procedure can be expressed within LINCOS itself. Therefore the system admits self-interpretation.

  8. Characterization of large size YBa2Cu3O7-δ films using magnetic field penetration

    Science.gov (United States)

    Almog, B.; Azoulay, M.; Castro, H.; Deutscher, G.

    2005-11-01

    High critical current density (jc) is one of the most important properties of high Tc superconducting thin films. Determining it is difficult especially in large films (2-3 inch). We propose a non-destructive and easy technique for measuring jc. From measurements of the magnetic moment in the middle of a superconducting film as a function of the external magnetic field, we calculate the macroscopic critical current density.

  9. Diversity of medium and large sized mammals in a Cerrado fragment of central Brazil

    Directory of Open Access Journals (Sweden)

    F.S. Campos

    2013-11-01

    Full Text Available Studies related to community ecology of medium and large mammals represent a priority in developing strategies for conservation of their habitats. Due to the significant ecological importance of these species, a concern in relation to anthropogenic pressures arises since their populations are vulnerable to hunting and fragmentation. In this study, we aimed to analyze the diversity of medium and large mammals in a representative area of the Cerrado biome, located in the National Forest of Silvânia, central Brazil, providing insights for future studies on the biodiversity and conservation of Cerrado mammals. Sampling was carried out by linear transects, search for traces, footprint traps and camera traps. We recorded 23 species, among which three are listed in threat categories (e.g., Myrmecophaga tridactyla, Chrysocyon brachyurus and Leopardus tigrinus. We registered 160 records in the study area, where the most frequently recorded species were Didelphis albiventris (30 records and Cerdocyon thous (28 records. Our results indicated that a small protected area of Cerrado can include a large and important percentage of the diversity of mammals in this biome, providing information about richness, abundance, spatial distribution and insights for future studies on the biodiversity and conservation of these biological communities.

  10. Dynamic globularization prediction during cogging process of large size TC11 titanium alloy billet with lamellar structure

    Institute of Scientific and Technical Information of China (English)

    Hong-wu SONG; Shi-hong ZHANG; Ming CHENG

    2014-01-01

    The flow behavior and dynamic globularization of TC11 titanium alloy during subtransus deformation are investigated through hot compression tests. A constitutive model is established based on physical-based hardening model and phenomenological softening model. And based on the recrystallization mechanisms of globularization, the Avrami type kinetics model is established for prediction of globularization fraction and globularized grain size under large strain subtransus deformation of TC11 alloy. As the preliminary application of the previous results, the cogging process of large size TC11 alloy billet is simulated. Based on subroutine development of the DEFORM software, the coupled simulation of one fire cogging process is developed. It shows that the predicted results are in good agreement with the experimental results in forging load and microstructure characteristic, which validates the reliability of the developed FEM subroutine models.

  11. Large Size GEM for Super Bigbite Spectrometer (SBS) Polarimeter for Hall A 12 GeV program at JLab

    CERN Document Server

    Gnanvo, Kondo; Nelyubin, Vladimir; Saenboonruang, Kiadtisak; Sacher, Seth; Wojtsekhowski, Bogdan

    2014-01-01

    We report on the R&D effort in the design and construction of a large size GEM chamber for the Proton Polarimeter of the Super Bigbite Spectrometer (SBS) in Hall A at Thomas Jefferson National Laboratory (JLab). The SBS Polarimeter trackers consist of two sets of four large chambers of size 200 cm x 60 cm. Each chamber is a vertical stack of four GEM modules with an active area of 60 cm x 50 cm. We have built and tested several GEM modules and we describe in this paper the design and construction of the final GEM as well as the preliminary results on performances from tests carried out in our detector lab and with test beams at Fermilab.

  12. Heritabilities and genetic correlations for litter size and semen traits in Czech Large White and Landrace pigs.

    Science.gov (United States)

    Wolf, J

    2010-09-01

    The objective of the present study was to estimate heritabilities and genetic correlations for semen and litter size traits using full animal model analyses. Litter size data were available from 28,485 Czech Large White and 10,410 Czech Landrace sows farrowing between 1995 and 2008. The number of litter records was 91,922 and 30,937, respectively. Records on semen traits (37,137 ejaculates from 778 Large White boars and 51,341 ejaculates from 841 Landrace boars) were available from 22 AI centers in the Czech Republic from 2000 to 2009. All calculations were carried out separately for each breed. Number of functional sperm was defined as total number of sperm times the fraction of motile sperm times (1 - the fraction of abnormal sperm). Among the semen traits, semen volume showed the greatest heritability (0.20 +/- 0.019 in Large White and 0.25 +/- 0.018 in Landrace), followed by sperm concentration with a heritability of 0.18 (SE = 0.012 and 0.014) in both breeds. The heritabilities of the remaining 4 traits (motility, percentage of abnormal sperm, total number of sperm, and number of functional sperm) were around 0.10 (SE = 0.016 to 0.031). Large negative genetic correlations were observed between semen volume and sperm concentration and between motility and percentage of abnormal sperm, especially in Large White. Positive and negative correlations among remaining semen traits were mostly of small magnitude. There was a tendency for increasing litter size to be associated with slight decreases in the total number of sperm and in the number of functional sperm, especially in the Large White breed (genetic correlations of -0.08 to -0.14 and -0.16 to -0.31, respectively, with SE between 0.100 and 0.114). Some of the correlations between semen and litter size traits (especially with the percentage of abnormal sperm) were breed-specific (positive up to 0.63 +/- 0.062 for Large White and negative until -0.41 +/- 0.106 in Landrace). Furthermore, parity

  13. Large-Sized Dye-Sensitized Solar Cells with TiO2 Cemented and Protected Silver Grids

    Science.gov (United States)

    Lan, Zhang; Wu, Jihuai; Lin, Jianming; Miaoliang

    2012-03-01

    Large-sized dye-sensitized solar cells were prepared with TiO2 cemented and protected Ag grids in the photo and counter electrodes. The addition of high conductive TiO2 cemented Ag grids can maintain high performance with the enlargement of the cells. The preparation of the compact TiO2 layer on the Ag grids can prevent the corrosion of the electrolyte, moreover, when it is prepared on the whole area of the photo electrode, it also can play as the blocking layer for further enhancing the performance of cells. The presented method shows a simple and efficient way to prepare high performance large single cells.

  14. Porous Carbon Fibers Containing Pores with Sizes Controlled at the Ångstrom Level by the Cavity Size of Pillar[6]arene.

    Science.gov (United States)

    Ogoshi, Tomoki; Yoshikoshi, Kumiko; Sueto, Ryuta; Nishihara, Hirotomo; Yamagishi, Tada-Aki

    2015-05-26

    We report a new synthesis method of fibrous carbon material with pores sizes that are precisely controlled at the Ångstrom level, by carbonization of two dimensional (2D) porous sheets of pillar[6]arenes. The 2D porous sheets were prepared by 2D supramolecular polymerization induced by oxidation of hydroquinone units of pillar[6]arenes. Owing to the hexagonal structure of pillar[6]arene, the assembly induced by 2D supramolecular polymerization gave hexagonal 2D porous sheets, and the highly ordered structure of the 2D porous sheets formed regular fibrous structures. Then, carbonization of the 2D porous sheets afforded fibrous carbon materials with micropores. The micropore size of the fibrous porous carbon prepared from pillar[6]arene was the same size as that of the starting material pillar[6]arene assembly.

  15. In-Class Extensive Reading Activity to Assist Self-Paced Learning in a Large Class-Size Environment

    OpenAIRE

    鬼田, 崇作

    2013-01-01

    The purpose of this paper is to show the effects an extensive reading activity had in assisting students in a self-paced learning, large class-size English environment. As the student body was diverse, encompassing varying levels of ability, learning styles, interests and proficiency, it is essential that teachers pay attention to these differences and adapt the materials to each learner's individual differences. However, it is difficult for a teacher to satisfy all of their individual studen...

  16. A method of manufacturing process modeling based on activity network for large-sized and complex products

    Institute of Scientific and Technical Information of China (English)

    LV Min; TONG Zhen-bo; WANG Gang

    2008-01-01

    Simulation technique is an efficient approach to realize the planning and scheduling of manufacturing process of products. An appropriate and efficient manufacturing process model is the basis and key of manufac-turing process simulation. By analyzing the features of large-sized and complex products, a method of manufac-turing process modeling based on activity network is presented and a mapping algorithm of translating BOM/ BOP into the manufacturing process model is designed in detail.

  17. Hypopigmentation Induced by Frequent Low-Fluence, Large-Spot-Size QS Nd:YAG Laser Treatments

    OpenAIRE

    Wong, Yisheng; Lee, Siong See Joyce; Goh, Chee Leok

    2015-01-01

    The Q-switched 1064-nm neodymium-doped yttrium aluminum garnet (QS 1064-nm Nd:YAG) laser is increasingly used for nonablative skin rejuvenation or "laser toning" for melasma. Multiple and frequent low-fluence, large-spot-size treatments are used to achieve laser toning, and these treatments are associated with the development of macular hypopigmentation as a complication. We present a case series of three patients who developed guttate hypomelanotic macules on the face after receiving laser t...

  18. A hybrid adaptive large neighborhood search heuristic for lot-sizing with setup times

    DEFF Research Database (Denmark)

    Muller, Laurent Flindt; Spoorendonk, Simon; Pisinger, David

    2012-01-01

    This paper presents a hybrid of a general heuristic framework and a general purpose mixed-integer programming (MIP) solver. The framework is based on local search and an adaptive procedure which chooses between a set of large neighborhoods to be searched. A mixed integer programming solver and its......, and the upper bounds found by the commercial MIP solver ILOG CPLEX using state-of-the-art MIP formulations. Furthermore, we improve the best known solutions on 60 out of 100 and improve the lower bound on all 100 instances from the literature...

  19. Micro powder injection molding——large scale production technology for micro-sized components

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Micro powder injection molding (μPIM),a miniaturized variant of powder injection molding,has advantages of shape complexity,applicability to many materials and good mechanical properties. Co-injection molding has been realized between met-als and ceramics on micro components,which become the first breakthrough within the PIM field. Combined with the prominent characteristics of high features/cost ratio,micro powder injection molding becomes a potential technique for large scale production of intricate and three-dimensional micro components or micro-structured components in microsystems technology (MST) field.

  20. Micro powder injection molding-large scale production technology for micro-sized components

    Institute of Scientific and Technical Information of China (English)

    YIN HaiQing; JIA ChengChang; QU XuanHui

    2008-01-01

    Micro powder injection molding (μPIM), a miniaturized variant of powder injection molding, has advantages of shape complexity, applicability to many materials and good mechanical properties. Co-injection molding has been realized between metals and ceramics on micro components, which become the first breakthrough within the PIM field. Combined with the prominent characteristics of high features/cost ratio, micro powder injection molding becomes a potential technique for large scale production of intricate and three-dimensional micro components or microstructured components in microsystems technology (MST) field.

  1. Large Size High Performance Transparent Amorphous Silicon Sensors for Laser Beam Position Detection and Monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Calderon, A.; Martinez Rivero, C.; Matorras, F.; Rodrigo, T.; Sobron, M.; Vila, I.; Virto; Alberdi, J.; Arce, P.; Barcala, J. M.; Calvo, E.; Ferrando, A.; Josa, M. I.; Luque, J. M.; Molinero, A.; Navarrete, J.; Oller, J. C.; Kohler, C.; Lutz, B.; Schubert, M. B.

    2006-09-04

    We present the measured performance of a new generation of semitransparente amorphous silicon position detectors. They have a large sensitive area (30 x 30 mm2) and show good properties such as a high response (about 20 mA/W), an intinsic position resolution better than 3 m, a spatial point reconstruction precision better than 10 m, deflection angles smaller than 10 rad and a transmission power in the visible and NIR higher than 70%. In addition, multipoint alignment monitoring, using up to five sensors lined along a light path of about 5 meters, can be achieved with a resolution better than 20m. (Author)

  2. Large-size high-performance transparent amorphous silicon sensors for laser beam position detection

    Energy Technology Data Exchange (ETDEWEB)

    Calderon, A. [Instituto de Fisica de Cantabria. CSIC-University of Cantabria, Santander (Spain); Martinez-Rivero, C. [Instituto de Fisica de Cantabria. CSIC-University of Cantabria, Santander (Spain); Matorras, F. [Instituto de Fisica de Cantabria. CSIC-University of Cantabria, Santander (Spain); Rodrigo, T. [Instituto de Fisica de Cantabria. CSIC-University of Cantabria, Santander (Spain); Sobron, M. [Instituto de Fisica de Cantabria. CSIC-University of Cantabria, Santander (Spain); Vila, I. [Instituto de Fisica de Cantabria. CSIC-University of Cantabria, Santander (Spain); Virto, A.L. [Instituto de Fisica de Cantabria. CSIC-University of Cantabria, Santander (Spain); Alberdi, J. [CIEMAT, Madrid (Spain); Arce, P. [CIEMAT, Madrid (Spain); Barcala, J.M. [CIEMAT, Madrid (Spain); Calvo, E. [CIEMAT, Madrid (Spain); Ferrando, A. [CIEMAT, Madrid (Spain)]. E-mail: antonio.ferrando@ciemat.es; Josa, M.I. [CIEMAT, Madrid (Spain); Luque, J.M. [CIEMAT, Madrid (Spain); Molinero, A. [CIEMAT, Madrid (Spain); Navarrete, J. [CIEMAT, Madrid (Spain); Oller, J.C. [CIEMAT, Madrid (Spain); Yuste, C. [CIEMAT, Madrid (Spain); Koehler, C. [Steinbeis-Transferzentrum fuer Angewandte Photovoltaik und Duennschichttechnik, Stuttgart (Germany); Lutz, B. [Steinbeis-Transferzentrum fuer Angewandte Photovoltaik und Duennschichttechnik, Stuttgart (Germany); Schubert, M.B. [Steinbeis-Transferzentrum fuer Angewandte Photovoltaik und Duennschichttechnik, Stuttgart (Germany); Werner, J.H. [Steinbeis-Transferzentrum fuer Angewandte Photovoltaik und Duennschichttechnik, Stuttgart (Germany)

    2006-09-15

    We present the measured performance of a new generation of semitransparent amorphous silicon position detectors. They have a large sensitive area (30x30mm{sup 2}) and show good properties such as a high response (about 20mA/W), an intrinsic position resolution better than 3{mu}m, a spatial-point reconstruction precision better than 10{mu}m, deflection angles smaller than 10{mu}rad and a transmission power in the visible and NIR higher than 70%.

  3. Dealing with large sample sizes: comparison of a new one spot dot blot method to western blot.

    Science.gov (United States)

    Putra, Sulistyo Emantoko Dwi; Tsuprykov, Oleg; Von Websky, Karoline; Ritter, Teresa; Reichetzeder, Christoph; Hocher, Berthold

    2014-01-01

    Western blot is the gold standard method to determine individual protein expression levels. However, western blot is technically difficult to perform in large sample sizes because it is a time consuming and labor intensive process. Dot blot is often used instead when dealing with large sample sizes, but the main disadvantage of the existing dot blot techniques, is the absence of signal normalization to a housekeeping protein. In this study we established a one dot two development signals (ODTDS) dot blot method employing two different signal development systems. The first signal from the protein of interest was detected by horseradish peroxidase (HRP). The second signal, detecting the housekeeping protein, was obtained by using alkaline phosphatase (AP). Inter-assay results variations within ODTDS dot blot and western blot and intra-assay variations between both methods were low (1.04-5.71%) as assessed by coefficient of variation. ODTDS dot blot technique can be used instead of western blot when dealing with large sample sizes without a reduction in results accuracy.

  4. Bivariate Mixed Effects Analysis of Clustered Data with Large Cluster Sizes.

    Science.gov (United States)

    Zhang, Daowen; Sun, Jie Lena; Pieper, Karen

    2016-10-01

    Linear mixed effects models are widely used to analyze a clustered response variable. Motivated by a recent study to examine and compare the hospital length of stay (LOS) between patients undertaking percutaneous coronary intervention (PCI) and coronary artery bypass graft (CABG) from several international clinical trials, we proposed a bivariate linear mixed effects model for the joint modeling of clustered PCI and CABG LOS's where each clinical trial is considered a cluster. Due to the large number of patients in some trials, commonly used commercial statistical software for fitting (bivariate) linear mixed models failed to run since it could not allocate enough memory to invert large dimensional matrices during the optimization process. We consider ways to circumvent the computational problem in the maximum likelihood (ML) inference and restricted maximum likelihood (REML) inference. Particularly, we developed an expected and maximization (EM) algorithm for the REML inference and presented an ML implementation using existing software. The new REML EM algorithm is easy to implement and computationally stable and efficient. With this REML EM algorithm, we could analyze the LOS data and obtained meaningful results.

  5. IMPACTS OF OWN BRANDS STRATEGY ON MANUFACTURER – RETAILER RELATIONSHIP: CASE STUDIES IN LARGE SIZE COMPANIES

    Directory of Open Access Journals (Sweden)

    Renato Telles

    2012-05-01

    Full Text Available The study of marketing and production strategy of own brand products requires an understanding of both the benefits gained by retailers and manufacturers involved in this activity and also the effects of this strategy on the relationship between these companies. According to this idea, a qualitative and descriptive work was conducted, based on six case studies, three of them on large product manufacturers and three on large retailers. The aim of this study is defined is threefold: (1 to analyze the expectations of manufacturers and retailers with their own brands’ current operations, (2 to analyze the expectations of manufacturers and retailers with their own brands’ future operations, and (3 to analyze the influence of the own brands adoption on the relationship between manufacturers and retailers. The results indicate that (a current operations are primarily based on economic reasons (market share, and use of spare capacity, (b future operations are perceived from a marketing perspective (survival, and (c the adoption of own brand strategy does not harm the relationship between the parties – both manufacturers and retailers –, unlike the earlier studies indicated.

  6. New screening software shows that most recent large 16S rRNA gene clone libraries contain chimeras.

    Science.gov (United States)

    Ashelford, Kevin E; Chuzhanova, Nadia A; Fry, John C; Jones, Antonia J; Weightman, Andrew J

    2006-09-01

    A new computer program, called Mallard, is presented for screening entire 16S rRNA gene libraries of up to 1,000 sequences for chimeras and other artifacts. Written in the Java computer language and capable of running on all major operating systems, the program provides a novel graphical approach for visualizing phylogenetic relationships among 16S rRNA gene sequences. To illustrate its use, we analyzed most of the large libraries of cloned bacterial 16S rRNA gene sequences submitted to the public repository during 2005. Defining a large library as one containing 100 or more sequences of 1,200 bases or greater, we screened 25 of the 28 libraries and found that all but three contained substantial anomalies. Overall, 543 anomalous sequences were found. The average anomaly content per clone library was 9.0%, 4% higher than that previously estimated for the public repository overall. In addition, 90.8% of anomalies had characteristic chimeric patterns, a rise of 25.4% over that found previously. One library alone was found to contain 54 chimeras, representing 45.8% of its content. These figures far exceed previous estimates of artifacts within public repositories and further highlight the urgent need for all researchers to adequately screen their libraries prior to submission. Mallard is freely available from our website at http://www.cardiff.ac.uk/biosi/research/biosoft/.

  7. Approved quarantine treatment for Hessian fly (Diptera: Cecidomyiidae) in large-size hay bales and Hessian fly and cereal leaf beetle (Coleoptera: Chrysomelidae) control by bale compression.

    Science.gov (United States)

    Yokoyama, Victoria Y

    2011-06-01

    A quarantine treatment using bale compression (32 kg/cm2 pressure) and phosphine fumigation (61 g/28.3 m3 aluminum phosphide for 7 d at 20 degrees C) was approved to control Hessian fly, Mayetiola destructor (Say), in large-size, polypropylene fabric-wrapped bales exported from the western states to Japan. No Hessian fly puparia (45,366) survived to the adult stage in infested wheat, Triticum aestivum L., seedlings exposed to the treatment in a large-scale commercial test. Daily temperatures (mean +/- SEM) inside and among bales in three test freight containers were 17.8 +/- 0.2 front top, 17.0 +/- 0.2 front bottom, 17.3 +/- 0.2 middle bale, 15.7 +/- 0.3 middle air, 18.5 +/- 0.1 back top, and 18.1 +/- 0.1 degrees C back bottom, allowing the fumigation temperature to be established at > or = 20 degrees C. Mean fumigant concentrations ranged from 208 to 340 ppm during the first 3 d and ranged from 328 to 461 ppm after 7 d of fumigation. Copper plate corrosion values inside the doors, and in the middle of the large-size bales in all locations indicated moderate exposure to hydrogen phosphide (PH3). PH3 residues were below the U.S. Environmental Protection Agency tolerance of 0.1 ppm in animal feeds. The research was approved by Japan and U.S. regulatory agencies, and regulations were implemented on 20 May 2005. Compression in large-size bale compressors resulted in 3-3.6 and 0% survival of Hessian fly puparia and cereal leaf beetle, Oulema melanopus (L.), respectively. Bale compression can be used as a single treatment for cereal leaf beetle and as a component in a systems approach for quarantine control of Hessian fly.

  8. The Caterpillar Project: A Large Suite of Milky Way Sized Halos

    CERN Document Server

    Griffen, Brendan F; Dooley, Gregory A; Gómez, Facundo A; Vogelsberger, Mark; O'Shea, Brian W; Frebel, Anna

    2015-01-01

    We present the largest number of Milky Way sized dark matter halos simulated at very high mass ($\\sim$$10^4$ M$_\\odot$/particle) and temporal resolution ($\\sim$5 Myrs/snapshot) done to date, quadrupling what is currently available in the literature. This initial suite consists of the first 24 halos of the $Caterpillar$ $Project$ (www.caterpillarproject.org) whose project goal of 60 - 70 halos will be made public when complete. We resolve $\\sim$20,000 gravitationally bound subhalos within the virial radius of each host halo. Over the ranges set by our spatial resolution our convergence is excellent and improvements were made upon current state-of-the-art halo finders to better identify substructure at such high resolutions (e.g., on average we recover $\\sim$4 subhalos in each host halo above 10$^8$ M$_\\odot$ which would have otherwise not been found using conventional methods). For our relaxed halos, the inner profiles are reasonably fit by Einasto profiles ($\\alpha$ = 0.169 $\\pm$ 0.023) though this depends on...

  9. Response of the Nevzorov hot wire probe in Arctic clouds dominated by very large droplet sizes

    Directory of Open Access Journals (Sweden)

    A. Schwarzenboeck

    2009-05-01

    Full Text Available During the airborne research mission ASTAR 2004 (Arctic Study of Tropospheric Aerosols, Clouds and Radiation performed over the island of Svalbard in the Arctic a constant-temperature hot-wire Nevzorov Probe designed for aircraft measurements, has been used onboard the aircraft POLAR 2. The Nevzorov probe measured liquid water (LWC and total condensed water content (TWC in supercooled liquid and partly mixed phase clouds, respectively. As for other hotwire probes the calculation of LWC and/or TWC (and thus the ice water content IWC has to take into account the collection efficiencies of the two separate sensors for LWC and TWC which both react differently with respect to cloud phase and what is even more difficult to quantify with respect to the size of ice and liquid cloud particles. The study demonstrates that during pure liquid cloud sequences the ASTAR data set of the Nevzorov probe allowed to improve the quantification of the collection efficiency, particularly of the LWC probe part with respect to water. The improved quantification of liquid water content should lead to improved retrievals of IWC content. Simultaneous retrievals of LWC and IWC are correlated with the asymmetry factor derived from the Polar Nephelometer instrument.

  10. A fast variational Gaussian wavepacket method: size-induced structural transitions in large neon clusters.

    Science.gov (United States)

    Georgescu, Ionuţ; Mandelshtam, Vladimir A

    2011-10-21

    The variational Gaussian wavepacket (VGW) approximation provides an alternative to path integral Monte Carlo for the computation of thermodynamic properties of many-body systems at thermal equilibrium. It provides a direct access to the thermal density matrix and is particularly efficient for Monte Carlo approaches, as for an N-body system it operates in a non-inflated 3N-dimensional configuration space. Here, we greatly accelerate the VGW method by retaining only the relevant short-range correlations in the (otherwise full) 3N × 3N Gaussian width matrix without sacrificing the accuracy of the fully coupled VGW method. This results in the reduction of the original O(N(3)) scaling to O(N(2)). The fast-VGW method is then applied to quantum Lennard-Jones clusters with sizes up to N = 6500 atoms. Following Doye and Calvo [JCP 116, 8307 (2002)] we study the competition between the icosahedral and decahedral structural motifs in Ne(N) clusters as a function of N.

  11. On the Effect of Hull Girder Flexibility on the Vertical Wave Bending Moment for Ultra Large Container Vessels

    DEFF Research Database (Denmark)

    Andersen, Ingrid Marie Vincent; Jensen, Jørgen Juncher

    2012-01-01

    analysis is done using the First Order Reliability Method (FORM) supplemented with Monte Carlo simulations. Furthermore, strip-theory calculations are compared to model tests in regular waves of different wave lengths using a segmented, flexible model of the case-ship and good agreement is obtained...... for the 9,400 TEU container ship used as case-ship in the EU project TULCS (Tools for Ultra Large Container Ships). A non-linear time-domain strip theory is used for the hydrodynamic analysis of the vertical bending moment amidships in sagging and hogging conditions for a flexible and a rigid modelling...... of the ship. The theory takes into account non-linear radiation forces (memory effects) through the use of a set of higher order differential equations. The non-linear hydrostatic restoring forces and non-linear Froude-Krylov forces are determined accurately at the instantaneous position of the ship...

  12. Evaluation of two sweeping methods for estimating the number of immature Aedes aegypti (Diptera: Culicidae in large containers

    Directory of Open Access Journals (Sweden)

    Margareth Regina Dibo

    2013-07-01

    Full Text Available Introduction Here, we evaluated sweeping methods used to estimate the number of immature Aedes aegypti in large containers. Methods III/IV instars and pupae at a 9:1 ratio were placed in three types of containers with, each one with three different water levels. Two sweeping methods were tested: water-surface sweeping and five-sweep netting. The data were analyzed using linear regression. Results The five-sweep netting technique was more suitable for drums and water-tanks, while the water-surface sweeping method provided the best results for swimming pools. Conclusions Both sweeping methods are useful tools in epidemiological surveillance programs for the control of Aedes aegypti.

  13. When David beats Goliath: the advantage of large size in interspecific aggressive contests declines over evolutionary time.

    Directory of Open Access Journals (Sweden)

    Paul R Martin

    Full Text Available Body size has long been recognized to play a key role in shaping species interactions. For example, while small species thrive in a diversity of environments, they typically lose aggressive contests for resources with larger species. However, numerous examples exist of smaller species dominating larger species during aggressive interactions, suggesting that the evolution of traits can allow species to overcome the competitive disadvantage of small size. If these traits accumulate as lineages diverge, then the advantage of large size in interspecific aggressive interactions should decline with increased evolutionary distance. We tested this hypothesis using data on the outcomes of 23,362 aggressive interactions among 246 bird species pairs involving vultures at carcasses, hummingbirds at nectar sources, and antbirds and woodcreepers at army ant swarms. We found the advantage of large size declined as species became more evolutionarily divergent, and smaller species were more likely to dominate aggressive contests when interacting with more distantly-related species. These results appear to be caused by both the evolution of traits in smaller species that enhanced their abilities in aggressive contests, and the evolution of traits in larger species that were adaptive for other functions, but compromised their abilities to compete aggressively. Specific traits that may provide advantages to small species in aggressive interactions included well-developed leg musculature and talons, enhanced flight acceleration and maneuverability, novel fighting behaviors, and traits associated with aggression, such as testosterone and muscle development. Traits that may have hindered larger species in aggressive interactions included the evolution of morphologies for tree trunk foraging that compromised performance in aggressive contests away from trunks, and the evolution of migration. Overall, our results suggest that fundamental trade-offs, such as those

  14. A polymer, random walk model for the size-distribution of large DNA fragments after high linear energy transfer radiation

    Science.gov (United States)

    Ponomarev, A. L.; Brenner, D.; Hlatky, L. R.; Sachs, R. K.

    2000-01-01

    DNA double-strand breaks (DSBs) produced by densely ionizing radiation are not located randomly in the genome: recent data indicate DSB clustering along chromosomes. Stochastic DSB clustering at large scales, from > 100 Mbp down to energy transfer (LET) radiation, are obtained. They are found to be non-linear when the dose becomes so large that there is a significant probability of overlapping or close juxtaposition, along one chromosome, for different DSB clusters from different tracks. The non-linearity is more evident for large fragments than for small. The DNAbreak results furnish an example of the RLC (randomly located clusters) analytic formalism, which generalizes the broken-stick fragment-size distribution of the random-breakage model that is often applied to low-LET data.

  15. Design and Construction of Large Size Micromegas Chambers for the ATLAS Upgrade of the Muon Spectrometer

    CERN Document Server

    Jeanneau, Fabien; The ATLAS collaboration

    2015-01-01

    Large area Micromegas detectors will be employed for the first time in high-energy physics experiments. A total surface of about 150 m2 of the forward regions of the Muon Spectrometer of the ATLAS detector at LHC will be equipped with 8-layer Micromegas modules. Each module extends over a surface from 2 to 3 m2 for a total active area of 1200 m2. Together with the small strip Thin Gap Chambers they will compose the two New Small Wheels, which will replace the innermost stations of the ATLAS endcap muon tracking system in the 2018/19 shutdown. In order to achieve a 15% transverse momentum resolution for 1 TeV muons, in addition to an excellent intrinsic resolution, the mechanical precision of each plane of the assembled module must be as good as 30 μm along the precision coordinate and 80 μm perpendicular to the chamber. In the prototyping towards the final configuration two similar quadruplets with dimensions 1.2×0.5 m2 have been built with the same structure as foreseen for the NSW upgrade. It represents ...

  16. Design and Construction of Large Size Micromegas Chambers for the ATLAS Upgrade of the Muon Spectrometer

    CERN Document Server

    Jeanneau, Fabien; The ATLAS collaboration

    2015-01-01

    Large area Micromegas detectors will be employed for the first time in high-energy physics experiments. A total surface of about 150 m2 of the forward regions of the Muon Spectrometer of the ATLAS detector at LHC will be equipped with 8-layer Micromegas modules. Each module extends over a surface from 2 to 3 m2 for a total active area of 1200 m2. Together with the small strip Thin Gap Chambers they will compose the two New Small Wheels, which will replace the innermost stations of the ATLAS endcap muon tracking system in the 2018/19 shutdown. In order to achieve a 15% transverse momentum resolution for 1 TeV muons, in addition to an excellent intrinsic resolution, the mechanical precision of each plane of the assembled module must be as good as 30 μm along the precision coordinate and 80 μm perpendicular to the chamber. All readout planes are segmented into strips with a pitch of 400 μm for a total of 4096 strips. In two of the four planes the strips are inclined by 1.5 ◦ and provide a measurement of the...

  17. Design and Construction of Large Size Micromegas Chambers for the Upgrade of the ATLAS Muon Spectrometer

    CERN Document Server

    Lösel, Philipp

    2015-01-01

    Large area Micromegas detectors will be employed for the first time in high-energy physics experiments. A total surface of about $\\mathbf{150~m^2}$ of the forward regions of the Muon Spectrometer of the ATLAS detector at LHC will be equipped with 8-layer Micromegas modules. Each layer covers more than $\\mathbf{2~m^2}$ for a total active area of $\\mathbf{1200~m^2}$. Together with the small strip Thin Gap Chambers they will compose the two New Small Wheels, which will replace the innermost stations of the ATLAS endcap muon tracking system in the 2018/19 shutdown. In order to achieve a 15$\\mathbf{\\%}$ transverse momentum resolution for $\\mathbf{1~TeV}$ muons, in addition to an excellent intrinsic resolution, the mechanical precision of each plane of the assembled module must be as good as $\\mathbf{30~\\mu m}$ along the precision coordinate and $\\mathbf{80~\\mu m}$ perpendicular to the chamber. The design and construction procedure of the Micromegas modules will be presented, as well as the design for the assembly ...

  18. Design and Construction of Large Size Micromegas Chambers for the ATLAS Upgrade of the Muon Spectrometer

    CERN Document Server

    Losel, Philipp Jonathan; The ATLAS collaboration

    2014-01-01

    Large area Micromegas detectors will be employed fo r the first time in high-energy physics experiments. A total surface of about 150 m$^2$ of the forward regions of the Muon Spectrometer of the ATLAS detector at LHC will be equipped with 8-layer Micromegas modules. Each module extends over a surface from 2 to 3 m$^2$ for a total active area of 1200 m$^2$. Together with the small strip Thin Gap Chambers they will compose the two New Small Wheels, which will replace the innermost stations of the ATLAS endcap muon tracking system in the 2018/19 shutdown. In order to achieve a 15% transverse momentum resol ution for 1 TeV muons, in addition to an excellent intrinsic resolution, the mechanical prec ision of each plane of the assembled module must be as good as 30 $\\mu$m along the precision coordi nate and 80 $\\mu$m perpendicular to the chamber. The design and construction procedure of the microm egas modules will be presented, as well as the design for the assembly of modules onto the New Small Wheel. Emphasis wi...

  19. Design and Construction of Large Size Micromegas Chambers for the ATLAS Upgrade of the Muon Spectrometer

    CERN Document Server

    Jeanneau, Fabien; The ATLAS collaboration

    2016-01-01

    Large area Micromegas detectors will be employed for the first time in high-energy physics experiments. A total surface area of about 150 m$^2$ of the forward regions (pseudo-rapidity coverage -- 1.3 $\\boldsymbol{< |\\eta| <}$ 2.7) of the Muon Spectrometer of the ATLAS detector at LHC will be equipped with 8-layer Micromegas modules. Each module extends over a surface from 2 to 3 m$^2$ for a total active area of 1200 m$^2$. Together with the small strip Thin Gap Chambers they will compose the two New Small Wheels (NSW), which will replace the innermost stations of the ATLAS endcap muon tracking system in the 2018/19 shutdown. In order to achieve a 15\\% transverse momentum resolution for 1 TeV muons, in addition to an excellent intrinsic position resolution, the mechanical precision of each plane of the assembled module must be $\\boldsymbol{30{\\mu}m}$ along the precision coordinate and $\\boldsymbol{80{\\mu}m}$ perpendicular to the chamber. All readout planes are segmented into strips with a pitch of $\\bold...

  20. Evaluation of different mechanical fruit harvesting systems and oil quality in very large size olive trees

    Directory of Open Access Journals (Sweden)

    Franco Famiani

    2014-11-01

    Full Text Available In 2006 and 2009, trials were carried out in the Apulia region in Southern Italy to evalu-ate the possibility of mechanizing olive harvesting in groves of old and very large trees. The trees belonged to the cultivars ‘Cellina di Nardò’ and ‘Ogliarola Salentina’. They were 60-100 years old and 7-9 m tall with a canopy volume of 140-360 m3. In the first half of November 2006, with a mechanical beater mounted on a tractor plus hand-held pneumatic combs, the harvesting yield was close to 90% of the total olives present in the canopy, and the harvesting working productivity was around 60 kg of harvested olives h-1 worker-1. With a self-propelled shaker attached to the main branches the harvesting yield was about 73% in ‘Cellina di Nardò’, and 40% in ‘Ogliarola Salentina’, while the harvesting working productivities were around 103 and 85 kg of harvested olives h-1 worker-1, respectively. In the second half of No-vember 2009, in ‘Cellina di Nardò’, with a mechanical beater mounted on a tractor plus nets on the ground or a catching frame (reversed umbrella mounted on another tractor, the harvesting yield was about 97%. The working productivity was about 98 kg of harvested olives h-1 worker-1 with the mechanical beater plus nets and around 133 kg of harvested olives h-1 worker-1 when the mechanical beater was combined with a reversed umbrella. The oil obtained from the mechanically harvested olives was always of high quality. A basic economic evaluation of the harvesting costs is also reported.

  1. Inferring Population Size History from Large Samples of Genome-Wide Molecular Data - An Approximate Bayesian Computation Approach.

    Directory of Open Access Journals (Sweden)

    Simon Boitard

    2016-03-01

    Full Text Available Inferring the ancestral dynamics of effective population size is a long-standing question in population genetics, which can now be tackled much more accurately thanks to the massive genomic data available in many species. Several promising methods that take advantage of whole-genome sequences have been recently developed in this context. However, they can only be applied to rather small samples, which limits their ability to estimate recent population size history. Besides, they can be very sensitive to sequencing or phasing errors. Here we introduce a new approximate Bayesian computation approach named PopSizeABC that allows estimating the evolution of the effective population size through time, using a large sample of complete genomes. This sample is summarized using the folded allele frequency spectrum and the average zygotic linkage disequilibrium at different bins of physical distance, two classes of statistics that are widely used in population genetics and can be easily computed from unphased and unpolarized SNP data. Our approach provides accurate estimations of past population sizes, from the very first generations before present back to the expected time to the most recent common ancestor of the sample, as shown by simulations under a wide range of demographic scenarios. When applied to samples of 15 or 25 complete genomes in four cattle breeds (Angus, Fleckvieh, Holstein and Jersey, PopSizeABC revealed a series of population declines, related to historical events such as domestication or modern breed creation. We further highlight that our approach is robust to sequencing errors, provided summary statistics are computed from SNPs with common alleles.

  2. Influence of local mechanical properties of high strength steel from large size forged ingot on ultrasonic wave velocities

    Science.gov (United States)

    Dupont-Marillia, Frederic; Jahazi, Mohamad; Lafreniere, Serge; Belanger, Pierre

    2017-02-01

    In the metallurgical industry, ultrasonic inspection is routinely used for the detection of defects. For the non-destructive inspection of small high strength steel parts, the material can be considered isotropic. However, when the size of the parts under inspection is large, the isotropic material hypothesis does not necessarily hold. The aim of this study is to investigate the effect of the variation in mechanical properties such as grain size, Young's modulus, Poissons ratio, chemical composition on longitudinal and transversal ultrasonic wave velocities. A 2 cm thick slice cut from a 40-ton bainitic steel ingot that was forged and heat treated was divided into 875 parallelepiped samples of 2x4x7 cm3. A metallurgical study has been performed to identify the phase and measure the grain size. Ultrasonic velocity measurements at 2.25 MHz for longitudinal and transversal waves were performed. The original location of the parallelepiped samples in the large forged ingot, and the measured velocities were used to produce an ultrasonic velocity map. Using a local isotropy assumption as well as the local density of the parallelepiped samples calculated from the chemical composition of the ingot provided by a previously published study, Youngs modulus and Poissons ratio were calculated from the longitudinal and transversal wave velocities. Micro-tensile test was used to validate Youngs modulus obtained by the ultrasonic wave velocity and an excellent agreement was observed.

  3. Feasibility of laparoscopic abdomino - perineal resection for large - sized anorectal cancers : A single - institution experience of 59 cases

    Directory of Open Access Journals (Sweden)

    Shukla Parul

    2009-03-01

    Full Text Available Background: Laparoscopic surgery for anorectal carcinoma is steadily gaining acceptance. While feasibility has already been reported, there are no reports addressing the impact of the actual size of large tumors on laparoscopic resectability . Aim: To assess the feasibility and short-term results (including oncological surrogate end points of performing laparoscopic abdomino-perineal resection (APR for large rectal cancers. Materials And Methods: Data of 59 patients undergoing laparoscopic APR (LAPR for anorectal malignancies were reviewed retrospectively. Outcomes were evaluated considering the surgical procedure, surface area of the tumor and short-term outcomes. Results: Of the 59 cases, LAPR could be completed in 53 (89.8% patients. Thirty-one (58.4% patients had Astler-Coller C2 stage disease. The mean surface area of the tumors was 24±17.5 (4-83 cm2. The number of median lymph nodes harvested per case was 12 (1-48. Circumferential resection margin (CRM was positive in 11 (20.7% patients. No mortality was reported. Conclusion: This appears to be the first report analyzing the impact of the size of the rectal tumor in LAPR. The data clearly indicates that LAPR is not hampered by the size of the tumor. There appears to be a need for preoperative radiotherapy and chemotherapy before undertaking surgery on larger tumors in view of the higher circumferential resection margin positivity.

  4. Efficient Algorithm for Locating and Sizing Series Compensation Devices in Large Transmission Grids: Model Implementation (PART 1)

    Energy Technology Data Exchange (ETDEWEB)

    Frolov, Vladimir [Moscow Inst. of Physics and Technology (MIPT), Moscow (Russian Federation); Backhaus, Scott N. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Chertkov, Michael [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-01-14

    We explore optimization methods for planning the placement, sizing and operations of Flexible Alternating Current Transmission System (FACTS) devices installed to relieve transmission grid congestion. We limit our selection of FACTS devices to Series Compensation (SC) devices that can be represented by modification of the inductance of transmission lines. Our master optimization problem minimizes the l1 norm of the inductance modification subject to the usual line thermal-limit constraints. We develop heuristics that reduce this non-convex optimization to a succession of Linear Programs (LP) which are accelerated further using cutting plane methods. The algorithm solves an instance of the MatPower Polish Grid model (3299 lines and 2746 nodes) in 40 seconds per iteration on a standard laptop—a speed up that allows the sizing and placement of a family of SC devices to correct a large set of anticipated congestions. We observe that our algorithm finds feasible solutions that are always sparse, i.e., SC devices are placed on only a few lines. In a companion manuscript, we demonstrate our approach on realistically-sized networks that suffer congestion from a range of causes including generator retirement. In this manuscript, we focus on the development of our approach, investigate its structure on a small test system subject to congestion from uniform load growth, and demonstrate computational efficiency on a realistically-sized network.

  5. Tritium release behavior of Li4SiO4 pebbles with high densities and large grain sizes

    Science.gov (United States)

    Ran, Guangming; Xiao, Chengjian; Chen, Xiaojun; Gong, Yu; Zhao, Linjie; Wang, Heyi; Wang, Xiaolin

    2017-08-01

    Tritium release behavior from the Li4SiO4 pebbles with high densities (∼96%TD) and large grain sizes (100-300 μm) fabricated by a melt-based method (the M-OSi sample) was investigated through out-of-pile experiments. Another batch of Li4SiO4 pebbles with relatively low densities (∼86%TD) and small grain sizes (10-50 μm) fabricated by a wet method (the W-OSi sample) was used for comparative study. Comparing with the W-OSi sample, the temperature of tritium release from the M-OSi sample was found much higher. Moreover, the fraction of tritium gas released from the M-OSi sample was much larger, especially under helium purge gas. The big differences between the characteristics of tritium release from the two batches of samples can be explained reasonably by the effect of grain size, implying that the grain size played an important role in the tritium release behavior. This study can provide a guideline for optimizing the fabrication process of Li4SiO4 pebbles.

  6. The Physics of Protoplanetesimal Dust Agglomerates. Vi. Erosion of Large Aggregates and its Consequences for the Dust-Size Distribution

    CERN Document Server

    Schräpler, Rainer

    2011-01-01

    Observed protoplanetary disks consist of a large amount of micrometer-sized particles. Dullemond and Dominik (2005) pointed out for the first time the difficulty in explaining the strong mid-IR excess of classical T-Tauri stars without any dust-retention mechanisms. Because high relative velocities in between micrometer-sized and macroscopic particles exist in protoplanetary disks, we present experimental results on the erosion of macroscopic agglomerates consisting of micrometer-sized spherical particles via the impact of micrometer-sized particles. We find that after an initial phase, in which an impacting particle erodes up to 10 particles of an agglomerate, the impacting particles compress the agglomerate's surface, which partly passivates the agglomerates against erosion. Due to this effect the erosion halts within our error bars for impact velocities up to ~30 m/s. For larger velocities, the erosion is reduced by an order of magnitude. This outcome is explained and confirmed by a numerical model. In a n...

  7. Efficient algorithm for locating and sizing series compensation devices in large power transmission grids: I. Model implementation

    Science.gov (United States)

    Frolov, Vladimir; Backhaus, Scott; Chertkov, Misha

    2014-10-01

    We explore optimization methods for planning the placement, sizing and operations of flexible alternating current transmission system (FACTS) devices installed to relieve transmission grid congestion. We limit our selection of FACTS devices to series compensation (SC) devices that can be represented by modification of the inductance of transmission lines. Our master optimization problem minimizes the l1 norm of the inductance modification subject to the usual line thermal-limit constraints. We develop heuristics that reduce this non-convex optimization to a succession of linear programs (LP) that are accelerated further using cutting plane methods. The algorithm solves an instance of the MatPower Polish Grid model (3299 lines and 2746 nodes) in 40 seconds per iteration on a standard laptop—a speed that allows the sizing and placement of a family of SC devices to correct a large set of anticipated congestions. We observe that our algorithm finds feasible solutions that are always sparse, i.e., SC devices are placed on only a few lines. In a companion manuscript, we demonstrate our approach on realistically sized networks that suffer congestion from a range of causes, including generator retirement. In this manuscript, we focus on the development of our approach, investigate its structure on a small test system subject to congestion from uniform load growth, and demonstrate computational efficiency on a realistically sized network.

  8. A LARGE-SCALE SIMULATION OF INTERNATIONAL MARITIME CONTAINER SHIPPING CONSIDERING OPTIMAL BEHAVIOR OF SHIPPERS AND OCEANGOING CARRIERS

    Science.gov (United States)

    Shibasaki, Ryuichi; Watanabe, Tomihiro; Ieda, Hitoshi

    This paper develops a large-scale simulation model of international maritime container shipping industry considering optimal behaviors of both shippers and oceangoing carriers, in order to measure impact of port and international logistics policies for each country including Japan. Concretely, the authors develop a short-term model (income maximization model of carriers) including shippers' choice of carrier when maritime cargo shipping demand between ports are given and a mid-term model (Nash equilibrium model of shippers and carriers) including shippers' choice of import/export port and route of hinterland transport and carriers' profit maximization behavior when cargo shipping demand between regions are given. The developed model is applied to the actual large-scale international maritime container shipping network in Eastern Asia. From a trial calculation based on the actual cargo shipping demand, the performance of the model is validated in terms of convergency and reproducibility. Also, the sensitivity of the model output taking the actual port policies into account is confirmed.

  9. Graphene-enhanced visible-light photocatalysis of large-sized CdS particles for wastewater treatment

    Science.gov (United States)

    Lü, Wei; Chen, Jie; Wu, Yao; Duan, Lianfeng; Yang, Yue; Ge, Xin

    2014-03-01

    The hybrid composites of graphene decorated by large-sized CdS particles (G/M-CdS) were prepared by a one-pot solvothermal route in which the reduction of graphite oxide into graphene was accompanied by the generation of microsized CdS particles. The structure and composition of the obtained nanocomposites were studied by means of X-ray diffraction, scanning electron microscopy, and transmission electron microscopy. The CdS particles with the average sizes of approximately 640 nm were formed on graphene sheets. The as-prepared composite was used as adsorbent to remove dye from wastewater using the organic dye Rhodamine B as the adsorbate. The G/M-CdS composite reveals a high photodegradation rate under visible light irradiation. Our results demonstrate that the G/M-CdS is very promising for removing organic dyes from wastewater.

  10. Possibility of Underwater Explosive Welding for Making Large-Sized Thin Metal Plate Clad by Overlapping Plates

    Science.gov (United States)

    Hokamoto, Kazuyuki; Mori, Akihisa; Fujita, Masahiro

    The authors have developed a new method of explosive welding using underwater shock wave for the welding of thin plate on a substrate. Considering the size limitation of the welding area in using the technique, the possibility of overlapping thin plates to make large-sized welding area is investigated. In general, the results for the welding of Inconel 600 on 304 stainless steel show a macroscopically successful weld, but the microstructure shows some melting spots caused due to the trapping of metal jet during the welding process when the welding condition is changed. The welding process is discussed based on the experimental results in comparison with some numerically simulated results obtained by AUTODYN-2D code.

  11. Pressure-Induced Oriented Attachment Growth of Large-Size Crystals for Constructing 3D Ordered Superstructures.

    Science.gov (United States)

    Wang, Jun; Lian, Gang; Si, Haibin; Wang, Qilong; Cui, Deliang; Wong, Ching-Ping

    2016-01-26

    Oriented attachment (OA), a nonclassical crystal growth mechanism, provides a powerful bottom-up approach to obtain ordered superstructures, which also demonstrate exciting charge transmission characteristic. However, there is little work observably pronouncing the achievement of 3D OA growth of crystallites with large size (e.g., submicrometer crystals). Here, we report that SnO2 3D ordered superstructures can be synthesized by means of a self-limited assembly assisted by OA in a designed high-pressure solvothermal system. The size of primary building blocks is 200-250 nm, which is significantly larger than that in previous results (normally pressure plays the key role in the formation of 3D configuration and fusion of adjacent crystals. Furthermore, this high-pressure strategy can be readily expanded to additional materials. We anticipate that the welded structures will constitute an ideal system with relevance to applications in optical responses, lithium ion battery, solar cells, and chemical sensing.

  12. Single-Seed Casting Large-Size Monocrystalline Silicon for High-Efficiency and Low-Cost Solar Cells

    Directory of Open Access Journals (Sweden)

    Bing Gao

    2015-09-01

    Full Text Available To grow high-quality and large-size monocrystal-line silicon at low cost, we proposed a single-seed casting technique. To realize this technique, two challenges—polycrystalline nucleation on the crucible wall and dislocation multiplication inside the crystal—needed to be addressed. Numerical analysis was used to develop solutions for these challenges. Based on an optimized furnace structure and operating conditions from numerical analysis, experiments were performed to grow monocrystalline silicon using the single-seed casting technique. The results revealed that this technique is highly superior to the popular high-performance multicrystalline and multiseed casting mono-like techniques.

  13. Single large or several small? The influence of prey size on feeding performance of Philodryas nattereri (Squamata: Serpentes

    Directory of Open Access Journals (Sweden)

    Sara Catunda Pereira

    2016-07-01

    Full Text Available This study aimed at evaluating the energetic return and feeding time on Philodryas nattereri kept in captivity. Snakes were fed biweekly for 60 days (four feeding trials, in two different feeding treatments (single and multiple prey items. The energetic return revealed no significant difference between the feeding treatments; however, we found a negative relationship between snake size and prey handling time during a feed using multiple prey items. In P. nattereri, when large preys are as easy to find as small ones, there seems to be no difference in energetic return.

  14. Large-size, high-uniformity, random silver nanowire networks as transparent electrodes for crystalline silicon wafer solar cells.

    Science.gov (United States)

    Xie, Shouyi; Ouyang, Zi; Jia, Baohua; Gu, Min

    2013-05-06

    Metal nanowire networks are emerging as next generation transparent electrodes for photovoltaic devices. We demonstrate the application of random silver nanowire networks as the top electrode on crystalline silicon wafer solar cells. The dependence of transmittance and sheet resistance on the surface coverage is measured. Superior optical and electrical properties are observed due to the large-size, highly-uniform nature of these networks. When applying the nanowire networks on the solar cells with an optimized two-step annealing process, we achieved as large as 19% enhancement on the energy conversion efficiency. The detailed analysis reveals that the enhancement is mainly caused by the improved electrical properties of the solar cells due to the silver nanowire networks. Our result reveals that this technology is a promising alternative transparent electrode technology for crystalline silicon wafer solar cells.

  15. Statistical Analysis of a Large Sample Size Pyroshock Test Data Set Including Post Flight Data Assessment. Revision 1

    Science.gov (United States)

    Hughes, William O.; McNelis, Anne M.

    2010-01-01

    The Earth Observing System (EOS) Terra spacecraft was launched on an Atlas IIAS launch vehicle on its mission to observe planet Earth in late 1999. Prior to launch, the new design of the spacecraft's pyroshock separation system was characterized by a series of 13 separation ground tests. The analysis methods used to evaluate this unusually large amount of shock data will be discussed in this paper, with particular emphasis on population distributions and finding statistically significant families of data, leading to an overall shock separation interface level. The wealth of ground test data also allowed a derivation of a Mission Assurance level for the flight. All of the flight shock measurements were below the EOS Terra Mission Assurance level thus contributing to the overall success of the EOS Terra mission. The effectiveness of the statistical methodology for characterizing the shock interface level and for developing a flight Mission Assurance level from a large sample size of shock data is demonstrated in this paper.

  16. An Ising iron(ii) chain exhibits a large finite-size energy barrier and "hard" magnetic behaviour.

    Science.gov (United States)

    Deng, Yi-Fei; Han, Tian; Xue, Wei; Hayashi, Naoaki; Kageyama, Hiroshi; Zheng, Yan-Zhen

    2017-01-31

    One-dimensional spin chains featuring strong axial anisotropic magnetism are promising candidates for isolatable and miniatured information storage materials, the so-called single-chain magnets (SCMs). Here we show a mixed azido/carboxylato bridged metamagnetic iron(ii) chain [Fe(N3)2(4-mpc)]n (4-mpc = N-methylpyridinium-4-carboxylate) with a large energy barrier of 150 K, a large remnant magnetization (1.55Nβ) and coercivity (1.7 T at 2 K) for homo-spin SCMs. Heat capacity and Mössbauer spectroscopy studies corroborate the intrinsic nature of SCM behavior regardless of weak interchain magnetic interactions, which lead to the coexistence of metamagnetism but not long-range magnetic ordering. Moreover, detailed magnetic investigations indicate that the system is not only within the "Ising limit" but also in the "finite-size" regime.

  17. Exact solution of the thermodynamics and size parameters of a polymer confined to a lattice of finite size: Large chain limit

    Energy Technology Data Exchange (ETDEWEB)

    Snyder, Chad R., E-mail: chad.snyder@nist.gov; Guttman, Charles M., E-mail: charles.guttman@nist.gov [Materials Science and Engineering Division, National Institute of Standards and Technology (NIST), Gaithersburg, Maryland 20899 (United States); Di Marzio, Edmund A., E-mail: edmund.dimarzio@nist.gov [Materials Science and Engineering Division, National Institute of Standards and Technology (NIST), Gaithersburg, Maryland 20899 (United States); Bio-Poly-Phase, 14205 Parkvale Road, Rockville, Maryland 20853 (United States)

    2014-01-21

    We extend the exact solutions of the Di Marzio-Rubin matrix method for the thermodynamic properties, including chain density, of a linear polymer molecule confined to walk on a lattice of finite size. Our extensions enable (a) the use of higher dimensions (explicit 2D and 3D lattices), (b) lattice boundaries of arbitrary shape, and (c) the flexibility to allow each monomer to have its own energy of attraction for each lattice site. In the case of the large chain limit, we demonstrate how periodic boundary conditions can also be employed to reduce computation time. Advantages to this method include easy definition of chemical and physical structure (or surface roughness) of the lattice and site-specific monomer-specific energetics, and straightforward relatively fast computations. We show the usefulness and ease of implementation of this extension by examining the effect of energy variation along the lattice walls of an infinite rectangular cylinder with the idea of studying the changes in properties caused by chemical inhomogeneities on the surface of the box. Herein, we look particularly at the polymer density profile as a function of temperature in the confined region for very long polymers. One particularly striking result is the shift in the critical condition for adsorption due to surface energy inhomogeneities and the length scale of the inhomogeneities; an observation that could have important implications for polymer chromatography. Our method should have applications to both copolymers and biopolymers of arbitrary molar mass.

  18. Calculating hyperfine couplings in large ionic crystals containing hundreds of QM atoms: subsystem DFT is the key.

    Science.gov (United States)

    Kevorkyants, Ruslan; Wang, Xiqiao; Close, David M; Pavanello, Michele

    2013-11-14

    We present an application of the linear scaling frozen density embedding (FDE) formulation of subsystem DFT to the calculation of isotropic hyperfine coupling constants (hfcc's) of atoms belonging to a guanine radical cation embedded in a guanine hydrochloride monohydrate crystal. The model systems range from an isolated guanine to a 15,000 atom QM/MM cluster where the QM region is comprised of 36 protonated guanine cations, 36 chlorine anions, and 42 water molecules. Our calculations show that the embedding effects of the surrounding crystal cannot be reproduced by small model systems nor by a pure QM/MM procedure. Instead, a large QM region is needed to fully capture the complicated nature of the embedding effects in this system. The unprecedented system size for a relativistic all-electron isotropic hfcc calculation can be approached in this work because the local nature of the electronic structure of the organic crystals considered is fully captured by the FDE approach.

  19. International Airport Impacts to Air Quality: Size and Related Properties of Large Increases in Ultrafine Particle Number Concentrations.

    Science.gov (United States)

    Hudda, N; Fruin, S A

    2016-04-05

    We measured particle size distributions and spatial patterns of particle number (PN) and particle surface area concentrations downwind from the Los Angeles International Airport (LAX) where large increases (over local background) in PN concentrations routinely extended 18 km downwind. These elevations were mostly comprised of ultrafine particles smaller than 40 nm. For a given downwind distance, the greatest increases in PN concentrations, along with the smallest mean sizes, were detected at locations under the landing jet trajectories. The smaller size of particles in the impacted area, as compared to the ambient urban aerosol, increased calculated lung deposition fractions to 0.7-0.8 from 0.5-0.7. A diffusion charging instrument (DiSCMini), that simulates alveolar lung deposition, measured a fivefold increase in alveolar-lung deposited surface area concentrations 2-3 km downwind from the airport (over local background), decreasing steadily to a twofold increase 18 km downwind. These ratios (elevated lung-deposited surface area over background) were lower than the corresponding ratios for elevated PN concentrations, which decreased from tenfold to twofold over the same distance, but the spatial patterns of elevated concentrations were similar. It appears that PN concentration can serve as a nonlinear proxy for lung deposited surface area downwind of major airports.

  20. Drug testing and flow cytometry analysis on a large number of uniform sized tumor spheroids using a microfluidic device

    Science.gov (United States)

    Patra, Bishnubrata; Peng, Chien-Chung; Liao, Wei-Hao; Lee, Chau-Hwang; Tung, Yi-Chung

    2016-02-01

    Three-dimensional (3D) tumor spheroid possesses great potential as an in vitro model to improve predictive capacity for pre-clinical drug testing. In this paper, we combine advantages of flow cytometry and microfluidics to perform drug testing and analysis on a large number (5000) of uniform sized tumor spheroids. The spheroids are formed, cultured, and treated with drugs inside a microfluidic device. The spheroids can then be harvested from the device without tedious operation. Due to the ample cell numbers, the spheroids can be dissociated into single cells for flow cytometry analysis. Flow cytometry provides statistical information in single cell resolution that makes it feasible to better investigate drug functions on the cells in more in vivo-like 3D formation. In the experiments, human hepatocellular carcinoma cells (HepG2) are exploited to form tumor spheroids within the microfluidic device, and three anti-cancer drugs: Cisplatin, Resveratrol, and Tirapazamine (TPZ), and their combinations are tested on the tumor spheroids with two different sizes. The experimental results suggest the cell culture format (2D monolayer vs. 3D spheroid) and spheroid size play critical roles in drug responses, and also demonstrate the advantages of bridging the two techniques in pharmaceutical drug screening applications.

  1. Breakdown of the Hume-Rothery Rules in Sub-Nanometer-Sized Ta-Containing Bimetallic Small Clusters

    Science.gov (United States)

    Miyajima, Ken; Fukushima, Naoya; Himeno, Hidenori; Yamada, Akira; Mafuné, Fumitaka

    2009-11-01

    The Hume-Rothery rules are empirical rules to predict the solid solubility of metals. We examined whether the rules hold for sub-nanometer-sized small particles. We prepared bimetallic cluster ions in the gas phase by a double laser ablation technique. Taking advantage of the magic compositions of the bimetallic cluster ions relating to the distinguished stabilities, the coalescence or the segregation of Ta and another element in the sub-nanometer-sized clusters was discussed. It was found that W, Nb, and Mo readily coalesce with Ta, while Ag, Al, Au, Co, Cu, Fe, Hf, Ni, Pt, Ti, and V are segregated from Ta. On the basis of these results, we concluded that the Hume-Rothery rules do not hold for sub-nanometer-sized particles.

  2. Thermal characterization of large size lithium-ion pouch cell based on 1d electro-thermal model

    Science.gov (United States)

    Vertiz, G.; Oyarbide, M.; Macicior, H.; Miguel, O.; Cantero, I.; Fernandez de Arroiabe, P.; Ulacia, I.

    2014-12-01

    Thermal management is one of the key factors to keep lithium-ion cells in optimum electrical performance, under safe working conditions and into a reasonably low ageing process. This issue is becoming particularly relevant due to the heterogeneous heat generation along the cell. Cell working temperature is determined by ambient temperature, heat generation and evacuation capacity. Therefore, thermal management is established by: i) the intrinsic thermal properties (heat capacity & thermal conductivity) and ii) the heat generation electro-thermal parameters (internal resistance, open circuit voltage & entropic factor). In this research, different methods - calculated and experimental - are used to characterize the main heat properties of a 14Ah -LiFePO4/graphite-commercial large sizes pouch cell. In order to evaluate the accuracy of methods, two comparisons were performed. First, Newman heat generation estimations were compared with experimental heat measurements. Secondly, empirical thermal cell behaviour was match with 1D electro-thermal model response. Finally, considering the results, the most adequate methodology to evaluate the key thermal parameters of a large size Lithium-ion pouch cell are proposed to be: i) pulse method for internal resistance, ii)heat loss method for entropic factor; and iii)experimental measurement (ARC calorimeter and C-177-97 standard method) for heat capacity and thermal conductivity.

  3. Electrochemical properties of large-sized pouch-type lithium ion batteries with bio-inspired organic cathode materials

    Science.gov (United States)

    Yeo, Jae-Seong; Yoo, Eun-Ji; Ha, Sang-Hyeon; Cheong, Dong-Ik; Cho, Sung-Baek

    2016-05-01

    To investigate the feasibility of scaling up bio-inspired organic materials as cathode materials in lithium ion batteries, large-sized pouch cells are successfully prepared via tape casting using lumichrome with an alloxazine structure and aqueous styrene butadiene rubber-carboxymethyl cellulose (SBR-CMC) binders. A battery module with a two-in-series, six-in-parallel (2S6P) configuration is also successfully fabricated and is able to power blue LEDs (850 mW). Lumichrome shows no structural changes during the fabrication processes used to produce the positive electrode. The large-sized pouch cells show two sets of cathodic and anodic peaks with average potentials of 2.58 V and 2.26 V vs. Li/Li+, respectively. The initial discharge capacities are 142 mAh g-1 and 148 mAh g-1 for ethylene carbonate-dimethyl carbonate (EC-DMC) and tetraethylene glycol dimethyl ether (TEGDME) electrolytes, respectively, similar to that of a coin cell (149 mAh g-1). The EC-DMC-injected pouch cells exhibit higher rate performance and cyclability than the TEGDME-injected ones. The TEGDME electrolyte is not suitable for lithium metal anodes because of electrolyte decomposition and subsequent cell swelling.

  4. Large Size Color-tunable Electroluminescence from Cationic Iridium Complexes-based Light-emitting Electrochemical Cells

    Science.gov (United States)

    Zeng, Qunying; Li, Fushan; Guo, Tailiang; Shan, Guogang; Su, Zhongmin

    2016-06-01

    Solution-processable light-emitting electrochemical cells (LECs) with simple device architecture have become an attractive candidate for application in next generation lighting and flat-panel displays. Herein, single layer LECs employing two cationic Ir(III) complexes showing highly efficient blue-green and yellow electroluminescence with peak current efficiency of 31.6 cd A‑1 and 40.6 cd A‑1, respectively, have been reported. By using both complexes in the device, color-tunable LECs with a single spectral peak in the wavelength range from 499 to 570 nm were obtained by varying their rations. In addition, the fabrication of efficient LECs was demonstrated based on low cost doctor-blade coating technique, which was compatible with the roll to roll fabrication process for the large size production. In this work, for the first time, 4 inch LEC devices by doctor-blade coating were fabricated, which exhibit the efficiencies of 23.4 cd A‑1 and 25.4 cd A‑1 for the blue-green and yellow emission, respectively. The exciting results indicated that highly efficient LECs with controllable color could be realized and find practical application in large size lighting and displays.

  5. Sexual-size dimorphism modulates the trade-off between exploiting food and wind resources in a large avian scavenger.

    Science.gov (United States)

    Alarcón, Pablo A E; Morales, Juan M; Donázar, José A; Sánchez-Zapata, José A; Hiraldo, Fernando; Lambertucci, Sergio A

    2017-09-13

    Animals are expected to synchronize activity routines with the temporal patterns at which resources appear in nature. Accordingly, species that depend on resources showing temporally mismatched patterns should be expected to schedule routines that balance the chances of exploiting each of them. Large avian scavengers depend on carcasses which are more likely available early in the morning, but they also depend on wind resources (i.e. uplifts) to subside flight which are stronger in afternoon hours. To understand how these birds deal with this potential trade-off, we studied the daily routines of GPS-tagged individuals of the world's largest terrestrial soaring scavenger, the Andean condor (Vultur gryphus). Andean condors vary largely in weight and show a huge sexual dimorphism that allowed us to evaluate the effect of sex and body size on their daily routines. We found that condors use an intermediate solution strategy between the best times to exploit carcasses and uplifts, with this strategy changing over the year. Bigger males scheduled earlier routines that aligned more closely with uplift availability compared to smaller females, resulting in a partial temporal segregation between sexes. Condors' routines reflect a sexual-size dependent trade-off that may underpin ecological and sociobiological traits of the studied population.

  6. Deformation and Recrystallization Behavior of the Cast Structure in Large Size, High Strength Steel Ingots: Experimentation and Modeling

    Science.gov (United States)

    Chadha, K.; Shahriari, D.; Tremblay, R.; Bhattacharjee, P. P.; Jahazi, M.

    2017-07-01

    Constitutive modeling of the ingot breakdown process of large size ingots of high strength steel was carried out through comprehensive thermomechanical processing using Gleeble 3800® thermomechanical simulator, finite element modeling (FEM), optical and electron back scatter diffraction (EBSD). For this purpose, hot compression tests in the range of 1473 K to 1323 K (1200 °C to 1050 °C) and strain rates of 0.25 to 2 s-1 were carried out. The stress-strain curves describing the deformation behavior of the dendritic microstructure of the cast ingot were analyzed in terms of the Arrhenius and Hansel-Spittel models which were implemented in Forge NxT 1.0® FEM software. The results indicated that the Arrhenius model was more reliable in predicting microstructure evolution of the as-cast structure during ingot breakdown, particularly the occurrence of dynamic recrystallization (DRX) process which was a vital parameter in estimating the optimum loads for forming of large size components. The accuracy and reliability of both models were compared in terms of correlation coefficient (R) and the average absolute relative error (ARRE).

  7. Deformation and Recrystallization Behavior of the Cast Structure in Large Size, High Strength Steel Ingots: Experimentation and Modeling

    Science.gov (United States)

    Chadha, K.; Shahriari, D.; Tremblay, R.; Bhattacharjee, P. P.; Jahazi, M.

    2017-09-01

    Constitutive modeling of the ingot breakdown process of large size ingots of high strength steel was carried out through comprehensive thermomechanical processing using Gleeble 3800® thermomechanical simulator, finite element modeling (FEM), optical and electron back scatter diffraction (EBSD). For this purpose, hot compression tests in the range of 1473 K to 1323 K (1200 °C to 1050 °C) and strain rates of 0.25 to 2 s-1 were carried out. The stress-strain curves describing the deformation behavior of the dendritic microstructure of the cast ingot were analyzed in terms of the Arrhenius and Hansel-Spittel models which were implemented in Forge NxT 1.0® FEM software. The results indicated that the Arrhenius model was more reliable in predicting microstructure evolution of the as-cast structure during ingot breakdown, particularly the occurrence of dynamic recrystallization (DRX) process which was a vital parameter in estimating the optimum loads for forming of large size components. The accuracy and reliability of both models were compared in terms of correlation coefficient (R) and the average absolute relative error (ARRE).

  8. Red blood cell size is inversely associated with leukocyte telomere length in a large multi-ethnic population.

    Directory of Open Access Journals (Sweden)

    Julia Kozlitina

    Full Text Available Although mutations in the genes encoding either the protein or RNA component of telomerase have been found in patients with various blood disorders, the impact of telomere length on hematopoiesis is less well understood for subjects from the general population. Here we have measured telomere lengths of genomic DNA isolated from circulating leukocytes of 3157 subjects, ranging from 18 to 85 years of age, enrolled in a large multiethnic population based study, the Dallas Heart Study 2. Shorter telomere lengths are marginally associated with lower red blood cell counts in this cohort, but are significantly associated with larger mean red blood cell size (as measured by the MCV, increased red blood cell distribution width (RDW, higher hemoglobin levels and lower platelet counts, even after correction for age, gender and ethnicity (p-values of 50 years vs. p = 0.0006 for <50 years of age. To our knowledge, this is the first report of an association between telomere length and red cell size in a large urban US population and suggests a biologic mechanism for macrocytosis of aging.

  9. An Examination of Teachers' Perceptions and Practice when Teaching Large and Reduced-Size Classes: Do Teachers Really Teach Them in the Same Way?

    Science.gov (United States)

    Harfitt, Gary James

    2012-01-01

    Class size research suggests that teachers do not vary their teaching strategies when moving from large to smaller classes. This study draws on interviews and classroom observations of three experienced English language teachers working with large and reduced-size classes in Hong Kong secondary schools. Findings from the study point to subtle…

  10. Measurements of {sup 222}Rn and{sup 220}Rn with a large size collector of radon progeny

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Qifan; Cheng, Jianping; Liu, Guilin; Zhu, Li [Tsinghua Univ., Beijing (China); Ja, Wenyi; Fang, Fang [Chengdu Univ. of Technology, Chengdu (China)

    2002-07-01

    People have paid more attention to radon since 1980s. Radon concentrations in high background radiation areas in the south are higher than others in China, especially {sup 220} Rn concentration is significantly high. Therefore, measurement of {sup 222} Rn and {sup 220} Rn concentration should be carried out there. I will introduce a large size collector of radon progeny and its applications in this paper. The collector is a sheet of polyvinyl chloride fibre with electrostatics of -500V {approx} -700V. Its size (60mm in diameter) is larger than others (26mm in diameter) that work as the same principle. The collector is more effective to adsorb radon progeny than most of others. The equipment of ZnS(Ag) Scintillation Counting System is available for large size collectors to detect radon progeny. Therefore its sensitivity of measurement is high than others. According to the different half life of radon progeny and based on both theory and experiment, a formula for discrimination and calculation of {sup 222} Rn and {sup 220} Rn concentrations was deduced. The {sup 222} Rn and {sup 220} Rn concentrations were surveyed with electrostatic collectors of radon progeny on the campus of commercial school and some other areas in Hainan, southern China. Neither {sup 222} Rn nor {sup 220} Rn concentrations were found significant high. However several faults underground were delineated. The collector is also used to study radon transportation. Results indicate that radon changes regularly with date when it has transported for a certain distance. Velocities of radon migration in the four media are quite different. Radon migrates more quickly in vertical tube than in the horizontal tube.

  11. Heat transfer analyses using computational fluid dynamics in the air blast freezing of guava pulp in large containers

    Directory of Open Access Journals (Sweden)

    W. M. Okita

    2013-12-01

    Full Text Available Heat transfer during the freezing of guava pulp conditioned in large containers such as in stacked boxes (34 L and buckets (20 L and unstacked drums (200 L is discussed. The air velocities across the cross-section of the tunnel were measured, and the values in the outlet of the evaporator were used as the initial conditions in computational fluid dynamics (CFD simulations. The model tested was turbulent standard k-ε. The CFD-generated convective heat transfer coefficients were mapped on the surfaces for each configuration and used in procedures for the calculation of freezing-time estimates. These estimates were compared with the experimental results for validation. The results showed that CFD determined representative coefficients and produced good correlations between the predicted and experimental values when applied to the freezing-time estimates for the box and drum configurations. The errors depended on the configuration and the adopted mesh (3-D grid construction.

  12. Locating single-point sources from arrival times containing large picking errors (LPEs): the virtual field optimization method (VFOM).

    Science.gov (United States)

    Li, Xi-Bing; Wang, Ze-Wei; Dong, Long-Jun

    2016-01-12

    Microseismic monitoring systems using local location techniques tend to be timely, automatic and stable. One basic requirement of these systems is the automatic picking of arrival times. However, arrival times generated by automated techniques always contain large picking errors (LPEs), which may make the location solution unreliable and cause the integrated system to be unstable. To overcome the LPE issue, we propose the virtual field optimization method (VFOM) for locating single-point sources. In contrast to existing approaches, the VFOM optimizes a continuous and virtually established objective function to search the space for the common intersection of the hyperboloids, which is determined by sensor pairs other than the least residual between the model-calculated and measured arrivals. The results of numerical examples and in-site blasts show that the VFOM can obtain more precise and stable solutions than traditional methods when the input data contain LPEs. Furthermore, we discuss the impact of LPEs on objective functions to determine the LPE-tolerant mechanism, velocity sensitivity and stopping criteria of the VFOM. The proposed method is also capable of locating acoustic sources using passive techniques such as passive sonar detection and acoustic emission.

  13. Impact on carbon footprint: a life cycle assessment of disposable versus reusable sharps containers in a large US hospital.

    Science.gov (United States)

    Grimmond, Terry; Reiner, Sandra

    2012-06-01

    Hospitals are striving to reduce their greenhouse gas (GHG) emissions. Targeting supply chain points and replacing disposable with reusable items are among recommendations to achieve this. Annually, US hospitals use 35 million disposable (DSC) or reusable sharps containers (RSC) generating GHG in their manufacture, use, and disposal. Using a life cycle assessment we assessed the global warming potential (GWP) of both systems at a large US hospital which replaced DSC with RSC. GHG emissions (CO(2), CH(4), N(2)O) were calculated in metric tons of CO(2) equivalents (MTCO(2)eq). Primary energy input data was used wherever possible and region-specific conversions used to calculate the GWP of each activity. Unit process GHGs were collated into manufacture, transport, washing, and treatment and disposal. The DSC were not recycled nor had recycled content. Chemotherapy DSC were used in both systems. Emission totals were workload-normalized per 100 occupied beds-yr and rate ratio analyzed using Fisher's test with P ≤0.05 and 95% confidence level. With RSC, the hospital reduced its annual GWP by 127 MTCO(2)eq (-83.5%) and diverted 30.9 tons of plastic and 5.0 tons of cardboard from landfill. Using RSC reduced the number of containers manufactured from 34,396 DSC annually to 1844 RSC in year one only. The study indicates sharps containment GWP in US hospitals totals 100,000 MTCO(2)eq and if RSC were used nationally the figure could fall by 64,000 MTCO(2)eq which, whilst only a fraction of total hospital GWP, is a positive, sustainable step.

  14. Cloning and Heterologous Expression of a Large-sized Natural Product Biosynthetic Gene Cluster in Streptomyces Species

    Science.gov (United States)

    Nah, Hee-Ju; Pyeon, Hye-Rim; Kang, Seung-Hoon; Choi, Si-Sun; Kim, Eung-Soo

    2017-01-01

    Actinomycetes family including Streptomyces species have been a major source for the discovery of novel natural products (NPs) in the last several decades thanks to their structural novelty, diversity and complexity. Moreover, recent genome mining approach has provided an attractive tool to screen potentially valuable NP biosynthetic gene clusters (BGCs) present in the actinomycetes genomes. Since many of these NP BGCs are silent or cryptic in the original actinomycetes, various techniques have been employed to activate these NP BGCs. Heterologous expression of BGCs has become a useful strategy to produce, reactivate, improve, and modify the pathways of NPs present at minute quantities in the original actinomycetes isolates. However, cloning and efficient overexpression of an entire NP BGC, often as large as over 100 kb, remain challenging due to the ineffectiveness of current genetic systems in manipulating large NP BGCs. This mini review describes examples of actinomycetes NP production through BGC heterologous expression systems as well as recent strategies specialized for the large-sized NP BGCs in Streptomyces heterologous hosts. PMID:28360891

  15. Size and CT density of iodine-containing ethosomal vesicles obtained by membrane extrusion: potential for use as CT contrast agents.

    Science.gov (United States)

    Na, Bomin; Choi, Byoung Wook; Kim, Bumsang

    2013-11-01

    Computed tomography (CT) is the primary non-invasive imaging technique used for most patients with suspected liver disease. In order to improve liver-specific imaging properties and prevent toxic effects in patients with compromised renal function, we investigated the encapsulation of iodine within ethosomal vesicles. As a first step in the development of novel contrast agents using ethosomes for CT imaging applications, iodine was entrapped within ethosomes and iodine-containing ethosomes of the desired size were obtained by extrusion using a polycarbonate membrane with a defined pore size. Ethosomes containing iodine showed a relatively high CT density, which decreased when they were extruded, due to the rupture and re-formation of the lipid bilayer of the ethosome. However, when a solution with a high iodine concentration was used as a dispersion media during the extrusion process, the decrease in CT density could be prevented. In addition, ethosomes containing iodine were taken up efficiently by macrophages, which are abundant in the liver, and these ethosomes exhibited no cellular toxicity. These results demonstrate that iodine could be entrapped within ethosomal vesicles, giving the ethosomes a relatively high CT density, and that the extrusion technique used in this study could conveniently and reproducibly produce ethosomal vesicles with a desired size. Therefore, ethosomes containing iodine, as prepared in this study, have potential as contrast agents with applications in CT imaging.

  16. Rheological and droplet size analysis of W/O/W multiple emulsions containing low concentrations of polymeric emulsifiers

    OpenAIRE

    Vasiljević, Dragana D.; JELENA V. PAROJČIĆ; Primorac, Marija M.; Vuleta, Gordana M.

    2009-01-01

    Multiple emulsions are complex dispersion systems which have many potential applications in pharmaceutics, cosmetics and the food industry. In practice, however, significant problems may arise because of their thermodynamic instability. In this study, W/O/W multiple emulsion systems containing low concentration levels of lipophilic polymeric primary emulsifiers cetyl dimethicone copolyol and PEG–30 dipolyhydroxystearate were evaluated. The concentrations of the primary emulsifiers were set at...

  17. Design Study-Thermoprocessed Food Containers Injection Molded Half-Size Steam Tray for Storage and Serving of Processed Foods

    Science.gov (United States)

    1981-10-01

    VINYL ACETATE COPOLYMERS) AND §177.1460 ( MELAMINE - FORMALDEHYDE RESINS IN MOLDED ARTICLES). CLEARED UNDER §177.1600 (POLYETHYLENE RESINS, CARBOXYL...NAPHTHALENE SULFONIC ACID- FORMALDEHYDE CON- DENSATE, SODIUM SALT. "t POLYSULFONE RESINS CLEARED UNDER §177.2500 (POLYSULFONE RESINS) AS ARTICLES OR...FOODS), §177.1210 (CLOSURES WITH SEALING GASKETS FOR FOOD CONTAINERS), §177.1850 fETHYLENE-VINYL ACETATE COPOLYMERS) AND §177.1460 ( MELAMINE - FORMALDEHYDE

  18. A combinatorial approach towards achieving an injectable, self-contained, phosphate-releasing scaffold for promoting biomineralization in critical size bone defects.

    Science.gov (United States)

    Nayef, Lamees; Mekhail, Mina; Benameur, Laila; Rendon, Juan S; Hamdy, Reggie; Tabrizian, Maryam

    2016-01-01

    An injectable, guanosine 5'-diphosphate (GDP)-crosslinked chitosan sponge was investigated as a drug delivery system (DDS) for accelerating biomineralization in critical size bone defects (CSBDs). Two approaches were examined both individually, and in combination, in order to achieve this goal. The first approach involved the encapsulation and release of Bone Morphogenetic Protein 7 (BMP-7), a powerful mineralization stimulant. Results confirmed that the rapid gelation of the chitosan sponge prompted high encapsulation of BMP-7 and provided a controlled release over a period of 30 days with no burst release. The second approach was aimed at encapsulating pyrophosphatase (PPtase) in the chitosan sponge to cleave pyrophosphate (PPi) - a mineralization inhibitor and a degradation by-product of the chitosan sponge - into phosphate ions (Pi). PPtase was successfully encapsulated in the chitosan sponge and was able to completely eliminate PPi from the media by cleaving them to Pi. Chitosan sponges releasing Pi into the media were shown to increase overall biomineralization fourfold as compared to controls, an amount equivalent to biomineralization caused by direct injection of 1μg of free BMP-7 to the cells. Even though the combined encapsulation of 1μg BMP-7 and PPtase in the sponges did not demonstrate an additional increase in biomineralization, encapsulation of low concentrations of BMP-7 can promote mesenchymal stem cell migration into the sponge after application in vivo. The findings suggest that the sponge-PPtase system likely allows excellent bone regeneration with lower concentrations of BMP-7, reducing risks and expense of the treatment. There are bone defects, known as critical size defects, which do not heal on their own and require a therapeutic intervention. The current commercially-available therapies use large quantities of growth factors, such as Bone Morphogenetic Proteins (BMPs), which makes them expensive and a source for a myriad of unwanted side

  19. Design of Quenching Process for Large-sized AISI P20 Steel Block Used as Plastic Die

    Institute of Scientific and Technical Information of China (English)

    Dongli SONG; Jianfeng GU; Jiansheng PAN; Xin YAO

    2006-01-01

    For large-sized AISI P20 steel block used as plastic die with a thickness of more than 200 mm, appropriate quenching processes are the key to obtain much thick hardened layer. In this paper, different quenching processes of AISI P20 steel block such as oil quenching, direct water quenching, water quenching with precooling and water quenching with pre-cooling and self-tempering were numerically investigated by computer simulation based on the detailed discussion on the mathematical models of quenching processes including partial differential equations of heat transfer, thermal physical properties, latent heat, heat transfer coefficient and calculation of phase transformation, The results show that the water quenching with pre-cooling and self-tempering process can not only effectively avoid quenching cracks, but also obtain deeper harden depth than oil quenching.

  20. Characterisation of Late Bronze Age large size shield nails by EDXRF, micro-EDXRF and X-ray digital radiography

    Energy Technology Data Exchange (ETDEWEB)

    Figueiredo, E., E-mail: elin@itn.pt [Instituto Tecnologico e Nuclear, Estrada Nacional 10, 2686-953 Sacavem (Portugal); CENIMAT/I3N, Departamento de Ciencia dos Materiais, Faculdade de Ciencias e Tecnologia, Universidade Nova de Lisboa, 2829-516 Monte de Caparica (Portugal); Departamento de Conservacao e Restauro, Faculdade de Ciencias e Tecnologia, Universidade Nova de Lisboa, 2829-516 Monte de Caparica (Portugal); Araujo, M.F. [Instituto Tecnologico e Nuclear, Estrada Nacional 10, 2686-953 Sacavem (Portugal); Silva, R.J.C. [CENIMAT/I3N, Departamento de Ciencia dos Materiais, Faculdade de Ciencias e Tecnologia, Universidade Nova de Lisboa, 2829-516 Monte de Caparica (Portugal); Senna-Martinez, J.C. [Centro de Arqueologia (Uniarq), Faculdade de Letras, Universidade de Lisboa, 1600-214 Lisboa (Portugal); Ines Vaz, J.L. [Departamento de Letras, Universidade Catolica, Estrada da Circunvalacao, 3504-505 Viseu (Portugal)

    2011-09-15

    In the present study six exceptional large size metallic nails, a dagger and a sickle from the Late Bronze Age archaeological site of Figueiredo das Donas (Central Portugal) have been analysed by EDXRF, micro-EDXRF and X-ray digital radiography for the study of material composition and technology of fabrication. The combination of these analytical and examination techniques showed that all artefacts are made of bronze with As, Sb and Pb impurities, and that the nails were most likely manufactured using the casting-on technique. These results reinforce the use of binary bronze by Late Bronze Age in the region, and the incorporation of new fabrication technologies that resulted from ancient spheres of interaction. - Highlights: > EDXRF, micro-EDXRF and X-ray digital radiography in cultural heritage studies. > Archaeometallurgical study of a Late Bronze Age artefact collection from Portugal. > Practise of a specific and traditional bronze metallurgy. > Appearance of technological innovations as the casting-on technique.

  1. Mechanics and cooling system for the camera of the Large Size Telescopes of the Cherenkov Telescope Array (CTA)

    CERN Document Server

    Delgado, Carlos; Diaz, Carlos; Hamer, Noemi; Hideyuki, Ohoka; Mirzoyan, Razmik; Teshima, Masahiro; Wetteskind, Holger

    2013-01-01

    Mechanics of the camera for the large size telescopes of CTA must protect and provide a stable environment for its instrumentation. This is achieved by a stiff support structure enclosed in an air and water tight volume. The structure is specially devised to facilitate extracting the power dissipated by the focal plane electronics while keeping its weight small enough to guarantee an optimum load on the telescope structure. A heat extraction system is designed to keep the electronics temperature within its optimal operation range, stable in time and homogeneous along the camera volume, whereas it is decoupled from the temperature in the telescope environment. In this contribution, we present the details of this system as well as its verification based in finite element analysis computations and tested prototypes. Finally, issues related to the integration of the camera mechanics and electronics will be dealt with.

  2. Characterisation of Late Bronze Age large size shield nails by EDXRF, micro-EDXRF and X-ray digital radiography.

    Science.gov (United States)

    Figueiredo, E; Araújo, M F; Silva, R J C; Senna-Martinez, J C; Vaz, J L Inês

    2011-09-01

    In the present study six exceptional large size metallic nails, a dagger and a sickle from the Late Bronze Age archaeological site of Figueiredo das Donas (Central Portugal) have been analysed by EDXRF, micro-EDXRF and X-ray digital radiography for the study of material composition and technology of fabrication. The combination of these analytical and examination techniques showed that all artefacts are made of bronze with As, Sb and Pb impurities, and that the nails were most likely manufactured using the casting-on technique. These results reinforce the use of binary bronze by Late Bronze Age in the region, and the incorporation of new fabrication technologies that resulted from ancient spheres of interaction.

  3. CAT 2 - An improved version of Cryogenic Analysis Tools for online and offline monitoring and analysis of large size cryostats

    Science.gov (United States)

    Pagliarone, C. E.; Uttaro, S.; Cappelli, L.; Fallone, M.; Kartal, S.

    2017-02-01

    CAT, Cryogenic Analysis Tools is a software package developed using LabVIEW and ROOT environments to analyze the performances of large size cryostats, where many parameters, input, and control variables need to be acquired and studied at the same time. The present paper describes how CAT works and which are the main improvements achieved in the new version: CAT 2. New Graphical User Interfaces have been developed in order to make the use of the full package more user-friendly as well as a process of resource optimization has been carried out. The offline analysis of the full cryostat performances is available both trough ROOT line command interface band also by using the new graphical interfaces.

  4. Long-term resource variation and group size: A large-sample field test of the Resource Dispersion Hypothesis

    Directory of Open Access Journals (Sweden)

    Morecroft Michael D

    2001-07-01

    Full Text Available Abstract Background The Resource Dispersion Hypothesis (RDH proposes a mechanism for the passive formation of social groups where resources are dispersed, even in the absence of any benefits of group living per se. Despite supportive modelling, it lacks empirical testing. The RDH predicts that, rather than Territory Size (TS increasing monotonically with Group Size (GS to account for increasing metabolic needs, TS is constrained by the dispersion of resource patches, whereas GS is independently limited by their richness. We conducted multiple-year tests of these predictions using data from the long-term study of badgers Meles meles in Wytham Woods, England. The study has long failed to identify direct benefits from group living and, consequently, alternative explanations for their large group sizes have been sought. Results TS was not consistently related to resource dispersion, nor was GS consistently related to resource richness. Results differed according to data groupings and whether territories were mapped using minimum convex polygons or traditional methods. Habitats differed significantly in resource availability, but there was also evidence that food resources may be spatially aggregated within habitat types as well as between them. Conclusions This is, we believe, the largest ever test of the RDH and builds on the long-term project that initiated part of the thinking behind the hypothesis. Support for predictions were mixed and depended on year and the method used to map territory borders. We suggest that within-habitat patchiness, as well as model assumptions, should be further investigated for improved tests of the RDH in the future.

  5. Occurrence of large and medium-sized mammals: Occurrence but not count models predict pronghorn distribution: Chapter 8

    Science.gov (United States)

    2011-01-01

    Management of medium to large-sized terrestrial mammals (Antilocapridae, Canidae, Cervidae, Leporidae, Mustelidae, Ochotonidae) in the western United States is multifaceted and complex. Species in this group generally are charismatic and provide economic opportunities, although others are considered a nuisance at one extreme or are listed as species of conservation concern at the other. Understanding the relative influence of land cover, habitat fragmentation, and human land use on their distribution during the breeding season is imperative to inform management decisions on land use and conservation planning for these species. We surveyed medium to large-sized sagebrush (Artemisia spp.)-associated mammal species in 2005 and 2006 on 141 random transects (mean length = 1.1 km) in the Wyoming Basins, an area undergoing rapid land cover transformation due to human actions including energy development. Overall, we observed 10 species but only obtained enough observations of pronghorn (Antilocapra americana) to develop spatially explicit distribution models. For pronghorn, occurrence related positively to proportion of sagebrush land cover within 0.27 km, mixed shrubland land cover within 3 km, riparian land cover within 5 km, Normalized Difference Vegetation Index (NDVI) within 0.27 km, road density within 5 km, and decay distance to power line corridors at 1 km, but negatively to salt-desert shrubland cover within 18 km and an interaction between sagebrush and NDVI within 0.27 km. We found excellent predictive capability of this model when evaluated with independent test data. The model provides a basis for assessing the effects of proposed development on pronghorn and can aid planning efforts to avoid or mitigate adverse effects on pronghorn.

  6. Intercomparison of Large-eddy Simulations of Arctic Mixed-phase Clouds: Importance of Ice Size Distribution Assumptions

    Energy Technology Data Exchange (ETDEWEB)

    Ovchinnikov, Mikhail; Ackerman, Andrew; Avramov, Alex; Cheng, Anning; Fan, Jiwen; Fridlind, Ann; Ghan, Steven J.; Harrington, Jerry Y.; Hoose, Corinna; Korolev, Alexei; McFarquhar, Greg; Morrison, H.; Paukert, Marco; Savre, Julien; Shipway, Ben; Shupe, Matthew D.; Solomon, Amy; Sulia, Kara

    2014-03-14

    Large-eddy simulations of mixed-phase Arctic clouds by 11 different models are analyzed with the goal of improving understanding and model representation of processes controlling the evolution of these clouds. In a case based on observations from the Indirect and Semi-Direct Aerosol Campaign (ISDAC), it is found that ice number concentration, Ni, exerts significant influence on the cloud structure. Increasing Ni leads to a substantial reduction in liquid water path (LWP) and potential cloud dissipation, in agreement with earlier studies. By comparing simulations with the same microphysics coupled to different dynamical cores as well as the same dynamics coupled to different microphysics schemes, it is found that the ice water path (IWP) is mainly controlled by ice microphysics, while the inter-model differences in LWP are largely driven by physics and numerics of the dynamical cores. In contrast to previous intercomparisons, all models here use the same ice particle properties (i.e., mass-size, mass-fall speed, and mass-capacitance relationships) and a common radiation parameterization. The constrained setup exposes the importance of ice particle size distributions (PSD) in influencing cloud evolution. A clear separation in LWP and IWP predicted by models with bin and bulk microphysical treatments is documented and attributed primarily to the assumed shape of ice PSD used in bulk schemes. Compared to the bin schemes that explicitly predict the PSD, schemes assuming exponential ice PSD underestimate ice growth by vapor deposition and overestimate mass-weighted fall speed leading to an underprediction of IWP by a factor of two in the considered case.

  7. ASIC-based architecture for the real-time computation of 2D convolution with large kernel size

    Science.gov (United States)

    Shao, Rui; Zhong, Sheng; Yan, Luxin

    2015-12-01

    Bidimensional convolution is a low-level processing algorithm of interest in many areas, but its high computational cost constrains the size of the kernels, especially in real-time embedded systems. This paper presents a hardware architecture for the ASIC-based implementation of 2-D convolution with medium-large kernels. Aiming to improve the efficiency of storage resources on-chip, reducing off-chip bandwidth of these two issues, proposed construction of a data cache reuse. Multi-block SPRAM to cross cached images and the on-chip ping-pong operation takes full advantage of the data convolution calculation reuse, design a new ASIC data scheduling scheme and overall architecture. Experimental results show that the structure can achieve 40× 32 size of template real-time convolution operations, and improve the utilization of on-chip memory bandwidth and on-chip memory resources, the experimental results show that the structure satisfies the conditions to maximize data throughput output , reducing the need for off-chip memory bandwidth.

  8. Development of a composite large-size SiPM (assembled matrix) based modular detector cluster for MAGIC

    Science.gov (United States)

    Hahn, A.; Mazin, D.; Bangale, P.; Dettlaff, A.; Fink, D.; Grundner, F.; Haberer, W.; Maier, R.; Mirzoyan, R.; Podkladkin, S.; Teshima, M.; Wetteskind, H.

    2017-02-01

    The MAGIC collaboration operates two 17 m diameter Imaging Atmospheric Cherenkov Telescopes (IACTs) on the Canary Island of La Palma. Each of the two telescopes is currently equipped with a photomultiplier tube (PMT) based imaging camera. Due to the advances in the development of Silicon Photomultipliers (SiPMs), they are becoming a widely used alternative to PMTs in many research fields including gamma-ray astronomy. Within the Otto-Hahn group at the Max Planck Institute for Physics, Munich, we are developing a SiPM based detector module for a possible upgrade of the MAGIC cameras and also for future experiments as, e.g., the Large Size Telescopes (LST) of the Cherenkov Telescope Array (CTA). Because of the small size of individual SiPM sensors (6 mm×6 mm) with respect to the 1-inch diameter PMTs currently used in MAGIC, we use a custom-made matrix of SiPMs to cover the same detection area. We developed an electronic circuit to actively sum up and amplify the SiPM signals. Existing non-imaging hexagonal light concentrators (Winston cones) used in MAGIC have been modified for the angular acceptance of the SiPMs by using C++ based ray tracing simulations. The first prototype based detector module includes seven channels and was installed into the MAGIC camera in May 2015. We present the results of the first prototype and its performance as well as the status of the project and discuss its challenges.

  9. Strain of Synechocystis PCC 6803 with Aberrant Assembly of Photosystem II Contains Tandem Duplication of a Large Chromosomal Region.

    Science.gov (United States)

    Tichý, Martin; Bečková, Martina; Kopečná, Jana; Noda, Judith; Sobotka, Roman; Komenda, Josef

    2016-01-01

    Cyanobacterium Synechocystis PCC 6803 represents a favored model organism for photosynthetic studies. Its easy transformability allowed construction of a vast number of Synechocystis mutants including many photosynthetically incompetent ones. However, it became clear that there is already a spectrum of Synechocystis "wild-type" substrains with apparently different phenotypes. Here, we analyzed organization of photosynthetic membrane complexes in a standard motile Pasteur collection strain termed PCC and two non-motile glucose-tolerant substrains (named here GT-P and GT-W) previously used as genetic backgrounds for construction of many photosynthetic site directed mutants. Although, both the GT-P and GT-W strains were derived from the same strain constructed and described by Williams in 1988, only GT-P was similar in pigmentation and in the compositions of Photosystem II (PSII) and Photosystem I (PSI) complexes to PCC. In contrast, GT-W contained much more carotenoids but significantly less chlorophyll (Chl), which was reflected by lower level of dimeric PSII and especially trimeric PSI. We found that GT-W was deficient in Chl biosynthesis and contained unusually high level of unassembled D1-D2 reaction center, CP47 and especially CP43. Another specific feature of GT-W was a several fold increase in the level of the Ycf39-Hlip complex previously postulated to participate in the recycling of Chl molecules. Genome re-sequencing revealed that the phenotype of GT-W is related to the tandem duplication of a large region of the chromosome that contains 100 genes including ones encoding D1, Psb28, and other PSII-related proteins as well as Mg-protoporphyrin methylester cyclase (Cycl). Interestingly, the duplication was completely eliminated after keeping GT-W cells on agar plates under photoautotrophic conditions for several months. The GT-W strain without a duplication showed no obvious defects in PSII assembly and resembled the GT-P substrain. Although, we do not exactly

  10. Fracture Toughness of Carbon Fiber Composites Containing Various Fiber Sizings and a Puncture Self-Healing Thermoplastic Matrix

    Science.gov (United States)

    Cano, Roberto J.; Grimsley, Brian W.; Ratcliffe, James G.; Gordon, Keith L.; Smith, Joseph G.; Siochi, Emilie J.

    2015-01-01

    Ongoing efforts at NASA Langley Research Center (LaRC) have resulted in the identification of several commercially available thermoplastic resin systems which self-heal after ballistic impact and through penetration. One of these resins, polybutylene graft copolymer (PBg), was selected as a matrix for processing with unsized carbon fibers to fabricate reinforced composites for further evaluation. During process development, data from thermo-physical analyses was utilized to determine a processing cycle to fabricate laminate panels, which were analyzed by photo microscopy and acid digestion. The process cycle was further optimized based on these results to fabricate panels for mechanical property characterization. The results of the processing development effort of this composite material, as well as the results of the mechanical property characterization, indicated that bonding between the fiber and PBg was not adequate. Therefore, three sizings were investigated in this work to assess their potential to improve fiber/matrix bonding compared to previously tested unsized IM7 fiber. Unidirectional prepreg was made at NASA LaRC from three sized carbon fibers and utilized to fabricate test coupons that were tested in double cantilever beam configurations to determine GIc fracture toughness.

  11. Large, detergent-resistant complexes containing murine antigens Thy-1 and Ly-6 and protein tyrosine kinase p56lck.

    Science.gov (United States)

    Bohuslav, J; Cinek, T; Horejsí, V

    1993-04-01

    A number of human and mouse leukocyte surface (glyco)proteins anchored in a membrane via glycosylphosphatidylinositol (GPI) moiety have been previously shown to be noncovalently associated with protein tyrosine kinases (Science 1991. 254: 1016; J. Biol. Chem. 1992. 267: 12317). Here we show that two murine antigens of this group, Thy-1 and Ly-6, implicated in the activation of the T cells, are associated with each other, with the kinase p56lck and with several of potential kinase substrates in very large, detergent-resistant complexes, the size of which is between 50 and 200 nm, as determined by ultrafiltration and gel chromatography. Experiments on simultaneous solubilization of mixed human and mouse cells rule out that the observed complexes are artifacts induced by the detergent. Complexes of similar composition and properties were obtained when either detergents Brij-58, Nonidet-P40 or 3-[(3-cholamidopropyl)-dimethylammonio]- 1-propane-sulfonate (Chaps) were used for solubilization of the cells, while octylglucoside at least partially dissociated them. These "GPI-complexes" may be essential for the well-known signal-transducing capacity of Thy-1 and Ly-6.

  12. MANUFACTURING AND CONTINUOUS IMPROVEMENT PERFORMANCE LEVEL IN PLANTS OF MEXICO; A COMPARATIVE ANALYSIS AMONG LARGE AND MEDIUM SIZE PLANTS

    Directory of Open Access Journals (Sweden)

    Carlos Monge

    2015-12-01

    Full Text Available A random and statistically significant sample of 40 medium (12 and large (28 manufacturing plants of Apodaca, Mexico were surveyed using a structured and validated questionnaire to investigate the level of implementation of lean manufacturing, sustainable manufacturing, continuous improvement and operational efficiency and environmental responsibility in them, it is important to mention it was found that performance in the mentioned philosophies, on the two categories of plants is low, however large plants show a better performance than medium plants. In both cases, it is worrying that in the highly industrialized municipality of Apodaca,  Mexico are not decisively adopting the philosophies mentioned, as this compromises in a global world, in the medium and long term the viability of the plants, particularly the medium size plants. Finally this article shows the results of the answers to the items of questionnaire for the plants managers, and this can be useful to the management of the plants to identify and to define specific improvement actions towards priority areas.

  13. Single molecule kinetics of horseradish peroxidase exposed in large arrays of femtoliter-sized fused silica chambers.

    Science.gov (United States)

    Ehrl, Benno N; Liebherr, Raphaela B; Gorris, Hans H

    2013-08-07

    Large arrays of femtoliter-sized chambers were etched into the surface of fused silica slides to enclose and observe hundreds of single horseradish peroxidase (HRP) molecules in parallel. Individual molecules of HRP oxidize the fluorogenic substrate Amplex Red to fluorescent resorufin in separate chambers, which was monitored by fluorescence microscopy. Photooxidation of Amplex Red and photobleaching of resorufin have previously limited the analysis of HRP in femtoliter arrays. We have strongly reduced these effects by optimizing the fluorescence excitation and detection scheme to yield accurate single molecule substrate turnover rates. We demonstrate the presence of long-lived kinetic states of single HRP molecules that are individually different for each molecule in the array. The large number of molecules investigated in parallel provides excellent statistics on the activity distribution in the enzyme population, which is similar to that reported for other enzymes such as β-galactosidase. We have further confirmed that the product formation of HRP in femtoliter chambers is 10-fold lower than that in the bulk solution due to the particular two-step redox reaction mechanism of HRP.

  14. Development of the photomultiplier tube readout system for the first Large-Sized Telescope of the Cherenkov Telescope Array

    CERN Document Server

    Masuda, Shu; Barrio, Juan Abel; Bigas, Oscar Blanch; Delgado, Carlos; Coromina, Lluís Freixas; Gunji, Shuichi; Hadasch, Daniela; Hatanaka, Kenichiro; Ikeno, Masahiro; Laguna, Jose Maria Illa; Inome, Yusuke; Ishio, Kazuma; Katagiri, Hideaki; Kubo, Hidetoshi; Martínez, Gustavo; Mazin, Daniel; Nakajima, Daisuke; Nakamori, Takeshi; Ohoka, Hideyuki; Paoletti, Riccardo; Ritt, Stefan; Rugliancich, Andrea; Saito, Takayuki; Sulanke, Karl-Heinz; Takeda, Junki; Tanaka, Manobu; Tanigawa, Shunsuke; Tejedor, Luis Ángel; Teshima, Masahiro; Tsuchiya, Yugo; Uchida, Tomohisa; Yamamoto, Tokonatsu

    2015-01-01

    The Cherenkov Telescope Array (CTA) is the next generation ground-based very high energy gamma-ray observatory. The Large-Sized Telescope (LST) of CTA targets 20 GeV -- 1 TeV gamma rays and has 1855 photomultiplier tubes (PMTs) installed in the focal plane camera. With the 23 m mirror dish, the night sky background (NSB) rate amounts to several hundreds MHz per pixel. In order to record clean images of gamma-ray showers with minimal NSB contamination, a fast sampling of the signal waveform is required so that the signal integration time can be as short as the Cherenkov light flash duration (a few ns). We have developed a readout board which samples waveforms of seven PMTs per board at a GHz rate. Since a GHz FADC has a high power consumption, leading to large heat dissipation, we adopted the analog memory ASIC "DRS4". The sampler has 1024 capacitors per channel and can sample the waveform at a GHz rate. Four channels of a chip are cascaded to obtain deeper sampling depth with 4096 capacitors. After a trigger ...

  15. Relaxation of localized excitons in CdSe/ZnSe heterostructures containing quantum islands of different sizes

    Energy Technology Data Exchange (ETDEWEB)

    Wachter, S.; Dal Don, B.; Schmidt, M.; Baldauf, M.; Dinger, A.; Kurtz, E.; Klingshirn, C.; Kalt, H. [Karlsruhe Univ. (T.H.) (Germany). Inst. fuer Angewandte Physik

    2001-03-08

    We report on localization dynamics of excitons in ensembles of self-organized CdSe islands embedded in ZnSe. The experimental methods employed are temperature dependent, spatially-resolved photoluminescence ({mu}-PL), spatially-integrated PL (macro-PL), as well as time-resolved PL (TRPL). We see the often observed non-monotonous shift of the PL maximum with temperature which we can explain by a redistribution of the excitons amongst the islands. The measured shift is compared with the exact shift of the bandgap deduced from {mu}-PL measurements and is found to depend strongly on island size and distribution. These transport processes are recovered in the temporal evolution of the PL. The decay time of the spectrally integrated PL reaches its maximum at exactly the same temperature at which the redshift of the macro-PL turns into a blueshift. (orig.)

  16. TRIXcell+, a new long-term boar semen extender containing whey protein with higher preservation capacity and litter size

    Directory of Open Access Journals (Sweden)

    B.M. van den Berg

    2014-02-01

    Full Text Available It was the aim of the present study to test whey as protective protein for the sperm cell in the long-term boar semen preservation medium TRIXcell. Analyses of sperm cell motility using computer-assisted semen analysis (CASA indicated that the whey protein Porex has a similar protective effect as bovine serum albumin (BSA in maintaining viability of stored boar sperm. Boar sperm diluted in TRIXcell+ maintains commercially acceptable motility (>60% for 10 days, while swine sperm diluted in the semen preservation medium Beltsville Thawing Solution (BTS maintains commercially acceptable motility (>60% for 3-5 days for most boars. To test the on-farm fertility performance of TRIXcell+ compared to BTS, inseminations were started on 35 commercial pig production farms in the summer of 2006. During the period of July 2006 until July 2012 for each farm and each calendar year the mean farrowing rate and litter size for semen diluted in TRIXcell+ and stored for 3-5 days was found higher than that of semen stored for 1-2 days in BTS. Based on data gained from a total of 583.749 sows inseminated through the years 2006-2012, the mean farrowing rate for semen diluted in TRIXcell+ and BTS was 90.4 ± 4.0 and 87.9 ± 3.6, respectively, which is not significantly different. Based on the same data, the mean total number of piglets born alive for semen diluted in TRIXcell+ and BTS was 14.2 ± 0.7 and 13.6 ± 0.6, respectively, which is significantly different. We conclude that whey protein can effectively be used in the long-term preservation medium TRIXcell resulting in a higher litter size.

  17. Nanometer scale pores similar in size to the entrance of the ribosomal exit cavity are a common feature of large RNAs

    Science.gov (United States)

    Rivas, Mario; Tran, Quyen; Fox, George E.

    2013-01-01

    The highly conserved peptidyl transferase center (PTC) of the ribosome contains an RNA pore that serves as the entrance to the exit tunnel. Analysis of available ribosome crystal structures has revealed the presence of multiple additional well-defined pores of comparable size in the ribosomal (rRNA) RNAs. These typically have dimensions of 1–2 nm, with a total area of ∼100 Å2 or more, and most are associated with one or more ribosomal proteins. The PTC example and the other rRNA pores result from the packing of helices. However, in the non-PTC cases the nitrogenous bases do not protrude into the pore, thereby limiting the potential for hydrogen bonding within the pore. Instead, it is the RNA backbone that largely defines the pore likely resulting in a negatively charged environment. In many but not all cases, ribosomal proteins are associated with the pores to a greater or lesser extent. With the exception of the PTC case, the large subunit pores are not found in what are thought to be the evolutionarily oldest regions of the 23S rRNA. The unusual nature of the PTC pore may reflect a history of being created by hybridization between two or more RNAs early in evolution rather than simple folding of a single RNA. An initial survey of nonribosomal RNA crystal structures revealed additional pores, thereby showing that they are likely a general feature of RNA tertiary structure. PMID:23940386

  18. Controllable fabrication of large-area 2D colloidal crystal masks with large size defect-free domains based on statistical experimental design

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, Yajuan, E-mail: yajuan@kth.se; Jönsson, Pär Göran; Zhao, Zhe, E-mail: zhezhao@kth.se

    2014-09-15

    Highlights: • 3000 μm{sup 2} defect-free HCP domain was successfully synthesized. • Relative humidity (RH) as well as the first rotational speed (v{sub a}) of the dual-speed procedure was identified as the quality-control parameters in spin coating. • 23% RH and v{sub a} = 1000 rpm were identified as the optimistic spin coating processing parameters for SiO{sub 2} HCP monolayer. • Statistical experimental design was demonstrated as one efficient strategy for multi-factor processing optimization. - Abstract: A large-area hexagonal packed monolayer of silica spheres with consistent defect-free domains of a size larger than 3000 μm{sup 2} was prepared by spin coating on glass substrates with the assistance of experimental design and statistical analysis. The ratio of the defect-free monolayer area to the square of sphere diameter is nearly two times of the previously reported maximum values. Several parameters involved in the spin coating systems were investigated. The results indicated that the relative humidity and the rotational speed of the first step of the spin coating had the most important impact on the ordering degree of the prepared monolayer. Furthermore, the ordering degree of the obtained monolayer increased with a decreased relative humidity. In addition, it reached an optimal value when the first rotational speed during spin coating reached a value of 1000 rpm. From this study, it can be concluded that statistical experimental design is an efficient strategy, especially for multi-factor phenomenon studies.

  19. Growing vertical ZnO nanorod arrays within graphite: efficient isolation of large size and high quality single-layer graphene.

    Science.gov (United States)

    Ding, Ling; E, Yifeng; Fan, Louzhen; Yang, Shihe

    2013-07-18

    We report a unique strategy for efficiently exfoliating large size and high quality single-layer graphene directly from graphite into DMF dispersions by growing ZnO nanorod arrays between the graphene layers in graphite.

  20. The effect of pupil size on stimulation of the melanopsin containing retinal ganglion cells, as evaluated by monochromatic pupillometry

    DEFF Research Database (Denmark)

    Nissen, Claus Jeppe; Sander, Birgit; Lund-Andersen, Henrik

    2012-01-01

    Purpose: To evaluate the influence of the size of the light exposed pupil in one eye on the pupillary light reflex of the other eye. Method: Using a monochromatic pupillometer, the left eye in each of 10 healthy subjects was exposed to 20¿s of monochromatic light of luminance 300¿cd/m(2), first red...... (660¿nm) and in a following session, blue (470¿nm) light. The consensual pupillary diameter in the right eye was continuously measured before, during, and after light exposure. Subsequently, Tropicamide 1% or Pilocarpine 2% was instilled into the left eye and when the pupil was either maximally dilated...... or contracted, the entire sequence of red and blue light exposure repeated. After at least 3¿days, when the effect of the eye drop had subsided, the entire experiment was repeated, this time employing the other substance. Results: Prior dilatation of the left pupil augmented the post light contraction to blue...

  1. Intercomparison of large-eddy simulations of Arctic mixed-phase clouds: Importance of ice size distribution assumptions

    Science.gov (United States)

    Ovchinnikov, Mikhail; Ackerman, Andrew S.; Avramov, Alexander; Cheng, Anning; Fan, Jiwen; Fridlind, Ann M.; Ghan, Steven; Harrington, Jerry; Hoose, Corinna; Korolev, Alexei; McFarquhar, Greg M.; Morrison, Hugh; Paukert, Marco; Savre, Julien; Shipway, Ben J.; Shupe, Matthew D.; Solomon, Amy; Sulia, Kara

    2014-03-01

    Large-eddy simulations of mixed-phase Arctic clouds by 11 different models are analyzed with the goal of improving understanding and model representation of processes controlling the evolution of these clouds. In a case based on observations from the Indirect and Semi-Direct Aerosol Campaign (ISDAC), it is found that ice number concentration, Ni, exerts significant influence on the cloud structure. Increasing Ni leads to a substantial reduction in liquid water path (LWP), in agreement with earlier studies. In contrast to previous intercomparison studies, all models here use the same ice particle properties (i.e., mass-size, mass-fall speed, and mass-capacitance relationships) and a common radiation parameterization. The constrained setup exposes the importance of ice particle size distributions (PSDs) in influencing cloud evolution. A clear separation in LWP and IWP predicted by models with bin and bulk microphysical treatments is documented and attributed primarily to the assumed shape of ice PSD used in bulk schemes. Compared to the bin schemes that explicitly predict the PSD, schemes assuming exponential ice PSD underestimate ice growth by vapor deposition and overestimate mass-weighted fall speed leading to an underprediction of IWP by a factor of two in the considered case. Sensitivity tests indicate LWP and IWP are much closer to the bin model simulations when a modified shape factor which is similar to that predicted by bin model simulation is used in bulk scheme. These results demonstrate the importance of representation of ice PSD in determining the partitioning of liquid and ice and the longevity of mixed-phase clouds.

  2. Intercomparison of Large-Eddy Simulations of Arctic Mixed-Phase Clouds: Importance of Ice Size Distribution Assumptions

    Science.gov (United States)

    Ovchinnikov, Mikhail; Ackerman, Andrew S.; Avramov, Alexander; Cheng, Anning; Fan, Jiwen; Fridlind, Ann M.; Ghan, Steven; Harrington, Jerry; Hoose, Corinna; Korolev, Alexei; McFarquhar, Greg M.; Morrison, Hugh; Paukert, Marco; Savre, Julien; Shipway, Ben J.; Shupe, Matthew D.; Solomon, Amy; Sulia, Kara

    2014-01-01

    Large-eddy simulations of mixed-phase Arctic clouds by 11 different models are analyzed with the goal of improving understanding and model representation of processes controlling the evolution of these clouds. In a case based on observations from the Indirect and Semi-Direct Aerosol Campaign (ISDAC), it is found that ice number concentration, Ni, exerts significant influence on the cloud structure. Increasing Ni leads to a substantial reduction in liquid water path (LWP), in agreement with earlier studies. In contrast to previous intercomparison studies, all models here use the same ice particle properties (i.e., mass-size, mass-fall speed, and mass-capacitance relationships) and a common radiation parameterization. The constrained setup exposes the importance of ice particle size distributions (PSDs) in influencing cloud evolution. A clear separation in LWP and IWP predicted by models with bin and bulk microphysical treatments is documented and attributed primarily to the assumed shape of ice PSD used in bulk schemes. Compared to the bin schemes that explicitly predict the PSD, schemes assuming exponential ice PSD underestimate ice growth by vapor deposition and overestimate mass-weighted fall speed leading to an underprediction of IWP by a factor of two in the considered case. Sensitivity tests indicate LWP and IWP are much closer to the bin model simulations when a modified shape factor which is similar to that predicted by bin model simulation is used in bulk scheme. These results demonstrate the importance of representation of ice PSD in determining the partitioning of liquid and ice and the longevity of mixed-phase clouds.

  3. Extending ALE3D, an Arbitrarily Connected hexahedral 3D Code, to Very Large Problem Size (U)

    Energy Technology Data Exchange (ETDEWEB)

    Nichols, A L

    2010-12-15

    As the number of compute units increases on the ASC computers, the prospect of running previously unimaginably large problems is becoming a reality. In an arbitrarily connected 3D finite element code, like ALE3D, one must provide a unique identification number for every node, element, face, and edge. This is required for a number of reasons, including defining the global connectivity array required for domain decomposition, identifying appropriate communication patterns after domain decomposition, and determining the appropriate load locations for implicit solvers, for example. In most codes, the unique identification number is defined as a 32-bit integer. Thus the maximum value available is 231, or roughly 2.1 billion. For a 3D geometry consisting of arbitrarily connected hexahedral elements, there are approximately 3 faces for every element, and 3 edges for every node. Since the nodes and faces need id numbers, using 32-bit integers puts a hard limit on the number of elements in a problem at roughly 700 million. The first solution to this problem would be to replace 32-bit signed integers with 32-bit unsigned integers. This would increase the maximum size of a problem by a factor of 2. This provides some head room, but almost certainly not one that will last long. Another solution would be to replace all 32-bit int declarations with 64-bit long long declarations. (long is either a 32-bit or a 64-bit integer, depending on the OS). The problem with this approach is that there are only a few arrays that actually need to extended size, and thus this would increase the size of the problem unnecessarily. In a future computing environment where CPUs are abundant but memory relatively scarce, this is probably the wrong approach. Based on these considerations, we have chosen to replace only the global identifiers with the appropriate 64-bit integer. The problem with this approach is finding all the places where data that is specified as a 32-bit integer needs to be

  4. Cellulose hydrolysis ability of a Clostridium thermocellum cellulosome containing small-size scaffolding protein CipA.

    Science.gov (United States)

    Deng, Lan; Mori, Yutaka; Sermsathanaswadi, Junjarus; Apiwatanapiwat, Waraporn; Kosugi, Akihiko

    2015-10-20

    Mutant Clostridium thermocellum YM72 that produces small-size scaffolding protein CipA (ssCipA) was isolated from wild-type YM4. Sequencing of ssCipA revealed that two domains, cohesin 6 and cohesin 7, were not present. Cellulosome prepared from YM72 exhibited a significant reduction of hydrolysis ability on crystalline celluloses such as Sigmacell type-20 and cellulose from Halocynthia. To investigate this influence in vitro, artificial cellulosomes were assembled as recombinant CipA (rCipA) and ssCipA (rssCipA) using native free-cellulosomal subunits. The cellulosome assembled using rssCipA showed a 1.8-fold decrease in the hydrolysis of crystalline cellulose compared with that of rCipA. However, no significant differences in the hydrolysis of carboxymethylcellulose and acid-swollen cellulose were observed. One protein band was missing from the complex that was assembled using rssCipA (confirmed by native-PAGE). The missing protein was identified as CelJ, which is a major cellulosomal subunit. This suggests that insufficient cooperation of CelJ into the cellulosome results in the significant reduction of hydrolysis toward crystalline cellulose. These results indicate that cohesin 6 and 7 may be responsible for the cooperation of CelJ through cohesin and dockerin interactions, and adequate cooperation of CelJ into the cellulosome is important for significant hydrolysis of crystalline cellulose. Copyright © 2015 Elsevier B.V. All rights reserved.

  5. A Kelch Motif-Containing Serine/Threonine Protein Phosphatase Determines the Large Grain QTL Trait in Rice

    Institute of Scientific and Technical Information of China (English)

    Zejun Hu; Haohua He; Shiyong Zhang; Fan Sun; Xiaoyun Xin; Wenxiang Wang; Xi Qian; Jingshui Yang; Xiaojin Luo

    2012-01-01

    A thorough understanding of the genetic basis of rice grain traits is critical for the improvement of rice (Oryza sativa L.) varieties.In this study,we generated an F2 population by crossing the large-grain japonica cultivar CW23 with Peiai 64 (PA64),an elite indica small-grain cultivar.Using QTL analysis,17 QTLs for five grain traits were detected on four different chromosomes.Eight of the QTLs were newly-identified in this study.In particular,qGL3-1,a newly-identified grain length QTL with the highest LOD value and largest phenotypic variation,was fine-mapped to the 17 kb region of chromosome 3.A serine/threonine protein phosphatase gene encoding a repeat domain containing two Kelch motifs was identified as the unique candidate gene corresponding to this QTL.A comparison of PA64 and CW23 sequences revealed a single nucleotide substitution (C→A) at position 1092 in exon 10,resulting in replacement of Asp (D) in PA64 with Glu (E) in CW23 for the 364th amino acid.This variation is located at the D position of the conserved sequence motif AVLDT of the Kelch repeat.Genetic analysis of a near-isogenic line (NIL) for qGL3-1 revealed that the allele qGL3-1 from CW23 has an additive or partly dominant effect,and is suitable for use in molecular marker-assisted selection.

  6. Long‐term creep rates on the Hayward Fault: evidence for controls on the size and frequency of large earthquakes

    Science.gov (United States)

    Lienkaemper, James J.; McFarland, Forrest S.; Simpson, Robert W.; Bilham, Roger; Ponce, David A.; Boatwright, John; Caskey, S. John

    2012-01-01

    The Hayward fault (HF) in California exhibits large (Mw 6.5–7.1) earthquakes with short recurrence times (161±65 yr), probably kept short by a 26%–78% aseismic release rate (including postseismic). Its interseismic release rate varies locally over time, as we infer from many decades of surface creep data. Earliest estimates of creep rate, primarily from infrequent surveys of offset cultural features, revealed distinct spatial variation in rates along the fault, but no detectable temporal variation. Since the 1989 Mw 6.9 Loma Prieta earthquake (LPE), monitoring on 32 alinement arrays and 5 creepmeters has greatly improved the spatial and temporal resolution of creep rate. We now identify significant temporal variations, mostly associated with local and regional earthquakes. The largest rate change was a 6‐yr cessation of creep along a 5‐km length near the south end of the HF, attributed to a regional stress drop from the LPE, ending in 1996 with a 2‐cm creep event. North of there near Union City starting in 1991, rates apparently increased by 25% above pre‐LPE levels on a 16‐km‐long reach of the fault. Near Oakland in 2007 an Mw 4.2 earthquake initiated a 1–2 cm creep event extending 10–15 km along the fault. Using new better‐constrained long‐term creep rates, we updated earlier estimates of depth to locking along the HF. The locking depths outline a single, ∼50‐km‐long locked or retarded patch with the potential for an Mw∼6.8 event equaling the 1868 HF earthquake. We propose that this inferred patch regulates the size and frequency of large earthquakes on HF.

  7. Performance of a large size triple GEM detector at high particle rate for the CBM Experiment at FAIR

    Science.gov (United States)

    Adak, Rama Prasad; Kumar, Ajit; Dubey, Anand Kumar; Chattopadhyay, Subhasis; Das, Supriya; Raha, Sibaji; Samanta, Subhasis; Saini, Jogender

    2017-02-01

    In CBM Experiment at FAIR, dimuons will be detected by a Muon Chamber (MUCH) consisting of segmented absorbers of varying widths and tracking chambers sandwiched between the absorber-pairs. In this fixed target heavy-ion collision experiment, operating at highest interaction rate of 10 MHz for Au+Au collision, the inner region of the 1st detector will face a particle rate of 1 MHz/cm2. To operate at such a high particle density, GEM technology based detectors have been selected for the first two stations of MUCH. We have reported earlier the performance of several small-size GEM detector prototypes built at VECC for use in MUCH. In this work, we report on a large GEM prototype tested with proton beam of momentum 2.36 GeV/c at COSY-Jülich Germany. The detector was read out using nXYTER operated in self-triggering mode. An efficiency higher than 96% at ΔVGEM = 375.2 V was achieved. The variation of efficiency with the rate of incoming protons has been found to vary within 2% when tested up to a maximum rate of 2.8 MHz/cm2. The gain was found to be stable at high particle rate with a maximum variation of ∼9%.

  8. Depletion of trophy large-sized sharks populations of the Argentinean coast, south-western Atlantic: insights from fishers' knowledge

    Directory of Open Access Journals (Sweden)

    Alejo Irigoyen

    Full Text Available Abstract Globally, sharks are impacted by a wide range of human activities, resulting in many populations being depleted. Trophy large-sized sharks of the Argentinean coast, the sand-tiger Carcharias taurus , the copper Carcharhinus brachyurus and the sevengill shark Notorynchus cepedianus are under intense sport and artisanal fishing since the 50's decade. However, the current and historical information for the assessment of its populations status is scarce. The aim of this work was to analyze the status of conservation of these species through the gathering of expert fishermen knowledge (FK on semi-structured interviews. Abundance variation perception between the beginning and the end of fishermen careers revealed a critical status for the species study (means variation between -77 and -90 %. Furthermore, a best day's catch analysis reinforce this result in the case of the sand tiger shark. The school shark Galeorhinus galeus was included on this work with the objective of contrast FK with formal information available of catch-per-unit-effort (CPUE time series. Both sources of information, despite are not comparable, shows declines ~ - 80%. The critical conservation situation of study species needs urgent management action, particularly for the san tiger shark which could became regionally extinct before the reaction of stakeholders occurs.

  9. Boys who pee the farthest have a large hollow head, a thin skin, and medium-size manhood

    Science.gov (United States)

    Attinger, Daniel; Lee, Vincent

    2016-11-01

    Following a recent trend of scientific studies on artwork, we study here the thermodynamics of a jetting thermometer made of ceramic, related to the Chinese tea culture. The thermometer represents a boy who "urinates" shortly after hot water is poured onto his head. Long jetting distance indicates if the water temperature is hot enough to brew tea. Here, a thermofluid model describes the jetting phenomenon of that pee-pee boy. The study demonstrates how thermal expansion of an interior air pocket causes jetting. The validity of assumptions underlying the Hagen-Poiseuille flow is discussed for urethra of finite length. A thermodynamic potential is shown to define maximum jetting velocity. Seven optimization criteria to maximize jetting distance are provided, including two dimensionless numbers. The dimensionless numbers are obtained by comparing the time scales of the internal pressure buildup due to heating, with that of pressure relief due to jetting. Optimization results show that longer jets are produced by large individuals, with low body mass index, with a boyhood of medium size inclined at an angle π/4. Analogies are drawn with pissing contests among humans and lobsters. The study ends by noting similitudes of working principle between that politically incorrect thermometer and Galileo Galilei's thermoscope.

  10. Age-related changes in resting-state networks of a large sample size of healthy elderly.

    Science.gov (United States)

    Huang, Chun-Chao; Hsieh, Wen-Jin; Lee, Pei-Lin; Peng, Li-Ning; Liu, Li-Kuo; Lee, Wei-Ju; Huang, Jon-Kway; Chen, Liang-Kung; Lin, Ching-Po

    2015-10-01

    Population aging is burdening the society globally, and the evaluation of functional networks is the key toward understanding cognitive changes in normal aging. However, the effect of age on default mode subnetworks has not been documented well, and age-related changes in many resting-state networks remain debatable. The purpose of this study was to propose more precise results for these issues using a large sample size. We used group-level meta-ICA analysis and dual regression approach for identifying resting-state networks from functional magnetic resonance imaging data of 430 healthy elderly participants. Partial correlation was used to observe age-related correlations within and between resting-state networks. In the default mode network, only the ventral subnetwork negatively correlated with age. Age-related decrease in functional connectivity was also noted in the auditory, right frontoparietal, sensorimotor, and visual medial networks. Further, some age-related increases and decreases were observed for between-network correlations. The results of this study suggest that only the ventral default mode subnetwork had age-related decline in functional connectivity and several reverse patterns of resting-state networks for network development. Understanding age-related network changes may provide solutions for the impact of population aging and diagnosis of neurodegenerative diseases. © 2015 John Wiley & Sons Ltd.

  11. Consecutive Short-Scan CT for Geological Structure Analog Models with Large Size on In-Situ Stage

    Science.gov (United States)

    Yang, Min; Zhang, Wen; Wu, Xiaojun; Wei, Dongtao; Zhao, Yixin; Zhao, Gang; Han, Xu; Zhang, Shunli

    2016-01-01

    For the analysis of interior geometry and property changes of a large-sized analog model during a loading or other medium (water or oil) injection process with a non-destructive way, a consecutive X-ray computed tomography (XCT) short-scan method is developed to realize an in-situ tomography imaging. With this method, the X-ray tube and detector rotate 270° around the center of the guide rail synchronously by switching positive and negative directions alternately on the way of translation until all the needed cross-sectional slices are obtained. Compared with traditional industrial XCTs, this method well solves the winding problems of high voltage cables and oil cooling service pipes during the course of rotation, also promotes the convenience of the installation of high voltage generator and cooling system. Furthermore, hardware costs are also significantly decreased. This kind of scanner has higher spatial resolution and penetrating ability than medical XCTs. To obtain an effective sinogram which matches rotation angles accurately, a structural similarity based method is applied to elimination of invalid projection data which do not contribute to the image reconstruction. Finally, on the basis of geometrical symmetry property of fan-beam CT scanning, a whole sinogram filling a full 360° range is produced and a standard filtered back-projection (FBP) algorithm is performed to reconstruct artifacts-free images. PMID:27537104

  12. Design of a prototype device to calibrate the Large Size Telescope camera of the Cherenkov Telescope Array

    CERN Document Server

    Iori, M; De Persio, F; Chatterjee, A; Ferrarotto, F; Nagesh, B K; Saha, L; Singh, B B

    2015-01-01

    The Cherenkov Telescope Array is a project that aims to exploring the highest energy region of electromagnetic spectrum. Two arrays, one for each hemisphere, will cover the full sky in a range from few tens of GeV to hundreds of TeV improving the sensitivity and angular resolution of the present operating arrays. A prototype of the Large Size Telescope (LST) for the study of gamma ray astronomy above some tens of GeV will be installed at the Canary Island of La Palma in 2016. The LST camera, made by an array of photomultipliers (PMTs), requires an accurate and systematic calibration over a wide dynamic range. In this contribution, we present an optical calibration system made by a 355 nm wavelength laser with 400 ps pulse width, 1 muJ output energy, up to 4k Hz repetition rate and a set of neutral density filters to obtain a wide range of photon intensities, up to 1000 photoelectrons/PMT, to be sent to the camera plane 28 m away. The number of photons after the diffuser of the calibration box, located in the ...

  13. Evolution of grain size distribution in high-redshift dusty quasars: Integrating large amounts of dust and unusual extinction curves

    CERN Document Server

    Nozawa, Takaya; Hirashita, Hiroyuki; Takeuchi, Tsutomu T

    2014-01-01

    The discoveries of huge amounts of dust and unusual extinction curves in high-redshift quasars (z > 4) cast challenging issues on the origin and properties of dust in the early universe. In this Letter, we investigate the evolutions of dust content and extinction curve in a high-z quasar, based on the dust evolution model taking account of grain size distribution. First, we show that the Milky-Way extinction curve is reproduced by introducing a moderate fraction (~0.2) of dense molecular-cloud phases in the interstellar medium for a graphite-silicate dust model. Then we show that the peculier extinction curves in high-z quasars can be explained by taking a much higher molecular-cloud fraction (>0.5), which leads to more efficient grain growth and coagulation, and by assuming amorphous carbon instead of graphite. The large dust content in high-z quasar hosts is also found to be a natural consequence of the enhanced dust growth. These results indicate that grain growth and coagulation in molecular clouds are ke...

  14. Hypoglycemic activity and oral bioavailability of insulin-loaded liposomes containing bile salts in rats: the effect of cholate type, particle size and administered dose.

    Science.gov (United States)

    Niu, Mengmeng; Lu, Yi; Hovgaard, Lars; Guan, Peipei; Tan, Yanan; Lian, Ruyue; Qi, Jianping; Wu, Wei

    2012-06-01

    Oral delivery of protein or polypeptide drugs remains a challenge due to gastric and enzymatic degradation as well as poor permeation across the intestinal epithelia. In this study, liposomes containing bile salts were developed as a new oral insulin delivery system. The primary goal was to investigate the effect of cholate type, particle size and dosage of the liposomes on the hypoglycemic activity and oral bioavailability. Liposomes containing sodium glycocholate (SGC), sodium taurocholate (STC) or sodium deoxycholate (SDC) were prepared by a reversed-phase evaporation method. After oral administration, all liposomes elicited a certain degree of hypoglycemic effect in parallel with an increase in blood insulin level. The highest oral bioavailability of approximately 8.5% and 11.0% could be observed with subcutaneous insulin as reference for SGC-liposomes in non-diabetic and diabetic rats, respectively. Insulin-loaded liposomes showed slower and sustained action over a period of over 20 h with peak time around 8-12h. SGC-liposomes showed higher oral bioavailability than liposomes containing STC or SDC and conventional liposomes. The hypoglycemic effect was size-dependent with the highest at 150 nm or 400 nm and was proportionally correlated to the administered dose. The results supported the hypothesis of insulin absorption as intact liposomes.

  15. Effects of combined silicon and molybdenum alloying on the size and evolution of microalloy precipitates in HSLA steels containing niobium and titanium

    Energy Technology Data Exchange (ETDEWEB)

    Pavlina, Erik J., E-mail: e.pavlina@deakin.edu.au [Deakin University, Institute for Frontier Materials, 75 Pigdons Road, Waurn Ponds, Victoria (Australia); Van Tyne, C.J.; Speer, J.G. [Colorado School of Mines, Advanced Steel Processing and Products Research Center, 1500 Illinois Street, Golden, CO (United States)

    2015-04-15

    The effects of combined silicon and molybdenum alloying additions on microalloy precipitate formation in austenite after single- and double-step deformations below the austenite no-recrystallization temperature were examined in high-strength low-alloy (HSLA) steels microalloyed with titanium and niobium. The precipitation sequence in austenite was evaluated following an interrupted thermomechanical processing simulation using transmission electron microscopy. Large (~ 105 nm), cuboidal titanium-rich nitride precipitates showed no evolution in size during reheating and simulated thermomechanical processing. The average size and size distribution of these precipitates were also not affected by the combined silicon and molybdenum additions or by deformation. Relatively fine (< 20 nm), irregular-shaped niobium-rich carbonitride precipitates formed in austenite during isothermal holding at 1173 K. Based upon analysis that incorporated precipitate growth and coarsening models, the combined silicon and molybdenum additions were considered to increase the diffusivity of niobium in austenite by over 30% and result in coarser precipitates at 1173 K compared to the lower alloyed steel. Deformation decreased the size of the niobium-rich carbonitride precipitates that formed in austenite. - Highlights: • We examine combined Si and Mo additions on microalloy precipitation in austenite. • Precipitate size tends to decrease with increasing deformation steps. • Combined Si and Mo alloying additions increase the diffusivity of Nb in austenite.

  16. Synthesis of Highly Ordered Large Size Mesoporous Silica and Effect of Stabilization as Enzyme Supports in Organic Solvent

    Institute of Scientific and Technical Information of China (English)

    B.Li; S.Inagaki; C.Miyazaki; H.Takahashi

    2000-01-01

    The FSM-16, MCM-41 and SBA-15 type hexagonal mesoporous silica materials having a highly arrange in order of the 2-dimensional structure were synthesized by using different silicon sources and surfactants. In the 2-dimensional silicate framework, pore size can be uniformly controlled by the combined use of the surfactants having different alkyl chains length and swelling agents (triisopropyl benzene). Pore-diameter of FSM-16 and MCM-41 can be expanded to 100 A, SBA-15 is 150 A. Crystal regularity decreased with increasing the pore-diameter in the FSM-16 derived from Kanemite (silicon source) and MCM-41 from water glass, its anionic char-acteristics on the pore wall may be higher than SBA-15 derived from oligomeric tetramethoxysilane (TMOS) is also reported. We have successfully used FSM-16 and MCM-41 as immobilizing agents of enzyme having cationic residues under isoelectric point. The level of adsorption of enzymes in the FSM-16 and MCM-41 was relatively high, but was low in the SBA-15 support. The mechanism of enzyme adsorption in mesopore was suggested to be the ionic interactions. In aqueous solutions, horseradish peroxidase (HRP) immobilized in FSM-16 containing 89A mesopore showed the highest loaded amounts(183mg/mg FSM),then a FSM-16 of pore-diameter 30 A only loaded a litter amounts (28mg/mg FSM) on the outside surface. The catalytic activity in organic solvent is high when HRP was immobilized in FSM-16 and MCM-41, but is low in case of SBA- 15.

  17. Problems and Countermeasures of Colloquial English Large Size Class Teach-ing of Higher Vocational Public English under the Constructivism Theory

    Institute of Scientific and Technical Information of China (English)

    WANG Yan-ping

    2014-01-01

    Based on the theory of constructivism, this article analyzes the open problems colloquial English large size class teach-ing of higher vocational public English and points out the countermeasures of colloquial English large-scale class teaching of high-er vocational public English.

  18. Effects of Large Class Size on Effective Teaching and Learning at the Winneba Campus of the UEW (University of Education, Winneba), Ghana

    Science.gov (United States)

    Yelkpieri, Daniel; Namale, Matthew; Esia-Donkoh, Kweku; Ofosu-Dwamena, Eric

    2012-01-01

    Large class size is one of the problems in the educational sector that developing nations have been grappling with. Ghana as a developing nation is no exception and has its own fair share of this problem at the pre-tertiary and tertiary levels of education. The sight of large class at the tertiary level is appalling and a headache to teachers at…

  19. An Artificial Neural Network Based Analysis of Factors Controlling Particle Size in a Virgin Coconut Oil-Based Nanoemulsion System Containing Copper Peptide.

    Science.gov (United States)

    Samson, Shazwani; Basri, Mahiran; Fard Masoumi, Hamid Reza; Abdul Malek, Emilia; Abedi Karjiban, Roghayeh

    2016-01-01

    A predictive model of a virgin coconut oil (VCO) nanoemulsion system for the topical delivery of copper peptide (an anti-aging compound) was developed using an artificial neural network (ANN) to investigate the factors that influence particle size. Four independent variables including the amount of VCO, Tween 80: Pluronic F68 (T80:PF68), xanthan gum and water were the inputs whereas particle size was taken as the response for the trained network. Genetic algorithms (GA) were used to model the data which were divided into training sets, testing sets and validation sets. The model obtained indicated the high quality performance of the neural network and its capability to identify the critical composition factors for the VCO nanoemulsion. The main factor controlling the particle size was found out to be xanthan gum (28.56%) followed by T80:PF68 (26.9%), VCO (22.8%) and water (21.74%). The formulation containing copper peptide was then successfully prepared using optimum conditions and particle sizes of 120.7 nm were obtained. The final formulation exhibited a zeta potential lower than -25 mV and showed good physical stability towards centrifugation test, freeze-thaw cycle test and storage at temperature 25°C and 45°C.

  20. An Artificial Neural Network Based Analysis of Factors Controlling Particle Size in a Virgin Coconut Oil-Based Nanoemulsion System Containing Copper Peptide

    Science.gov (United States)

    Samson, Shazwani; Basri, Mahiran; Fard Masoumi, Hamid Reza; Abdul Malek, Emilia; Abedi Karjiban, Roghayeh

    2016-01-01

    A predictive model of a virgin coconut oil (VCO) nanoemulsion system for the topical delivery of copper peptide (an anti-aging compound) was developed using an artificial neural network (ANN) to investigate the factors that influence particle size. Four independent variables including the amount of VCO, Tween 80: Pluronic F68 (T80:PF68), xanthan gum and water were the inputs whereas particle size was taken as the response for the trained network. Genetic algorithms (GA) were used to model the data which were divided into training sets, testing sets and validation sets. The model obtained indicated the high quality performance of the neural network and its capability to identify the critical composition factors for the VCO nanoemulsion. The main factor controlling the particle size was found out to be xanthan gum (28.56%) followed by T80:PF68 (26.9%), VCO (22.8%) and water (21.74%). The formulation containing copper peptide was then successfully prepared using optimum conditions and particle sizes of 120.7 nm were obtained. The final formulation exhibited a zeta potential lower than -25 mV and showed good physical stability towards centrifugation test, freeze-thaw cycle test and storage at temperature 25°C and 45°C. PMID:27383135

  1. An Artificial Neural Network Based Analysis of Factors Controlling Particle Size in a Virgin Coconut Oil-Based Nanoemulsion System Containing Copper Peptide.

    Directory of Open Access Journals (Sweden)

    Shazwani Samson

    Full Text Available A predictive model of a virgin coconut oil (VCO nanoemulsion system for the topical delivery of copper peptide (an anti-aging compound was developed using an artificial neural network (ANN to investigate the factors that influence particle size. Four independent variables including the amount of VCO, Tween 80: Pluronic F68 (T80:PF68, xanthan gum and water were the inputs whereas particle size was taken as the response for the trained network. Genetic algorithms (GA were used to model the data which were divided into training sets, testing sets and validation sets. The model obtained indicated the high quality performance of the neural network and its capability to identify the critical composition factors for the VCO nanoemulsion. The main factor controlling the particle size was found out to be xanthan gum (28.56% followed by T80:PF68 (26.9%, VCO (22.8% and water (21.74%. The formulation containing copper peptide was then successfully prepared using optimum conditions and particle sizes of 120.7 nm were obtained. The final formulation exhibited a zeta potential lower than -25 mV and showed good physical stability towards centrifugation test, freeze-thaw cycle test and storage at temperature 25°C and 45°C.

  2. The main postulates of adaptive correction of distortions of the wave front in large-size optical systems

    Directory of Open Access Journals (Sweden)

    V. V. Sychev

    2014-01-01

    Full Text Available In the development of optical telescopes, striving to increase the penetrating power of a telescope has been always the main trend. A real way to solve this problem is to raise the quality of the image (reduction of the image angular size under real conditions of distorting factor and increase a diameter of the main mirror. This is counteracted by the various distorting factors or interference occurring in realtime use of telescopes, as well as by complicated manufacturing processes of large mirrors.It is shown that the most effective method to deal with the influence of distorting factors on the image quality in the telescope is the minimization (through selecting the place to mount a telescope and choosing the rational optical scheme, creating materials and new technologies, improving a design, unloading the mirrors, mounting choice, etc., and then the adaptive compensation of remaining distortions.It should be noted that a domestic concept to design large-sized telescopes allows us to use, in our opinion, the most efficient ways to do this. It means to abandon the creation of "an absolutely rigid and well-ordered" design, providing the passively aligned state telescope optics under operating conditions. The design must just have such a level of residual deformations that their effect can be efficiently compensated by the adaptive system using the segmented elements of the primary mirror and the secondary mirror as a corrector.It has been found that in the transmission optical systems to deliver laser power to a remote object, it is necessary not only to overcome the distorting effect of factors inherent in optical information systems, but, additionally, find a way to overcome a number of new difficulties. The main ones have been identified to be as follows:• the influence of laser radiation on the structure components and the propagation medium and, as a consequence, the opposite effect of the structure components and the propagation

  3. Er3+-doped transparent glass ceramics containing micron-sized SrF2 crystals for 2.7 μm emissions

    Science.gov (United States)

    Jiang, Yiguang; Fan, Jintai; Jiang, Benxue; Mao, Xiaojian; Tang, Junzhou; Xu, Yinsheng; Dai, Shixun; Zhang, Long

    2016-07-01

    Er3+-doped transparent glass ceramics containing micron-sized SrF2 crystals were obtained by direct liquid-phase sintering of a mixture of SrF2 powders and precursor glass powders at 820 °C for 15 min. The appearance and microstructural evolution of the SrF2 crystals in the resulting glass ceramics were investigated using X-ray diffraction, field-emission scanning electron microscopy and transmission microscopy. The SrF2 crystals are ~15 μm in size and are uniformly distributed throughout the fluorophosphate glass matrix. The glass ceramics achieve an average transmittance of 75% in the visible region and more than 85% in the near-IR region. The high transmittance of the glass ceramics results from matching the refractive index of the SrF2 with that of the precursor glass. Energy dispersive spectroscopy, photoluminescence spectra, and photoluminescence lifetimes verified the incorporation of Er3+ into the micron-sized SrF2 crystals. Intense 2.7 μm emissions due to the 4I11/2 → 4I13/2 transition were observed upon excitation at 980 nm using a laser diode. The maximum value of the emission cross section of Er3+ around 2.7 μm is more than 1.2 × 10‑20 cm2, which indicates the potential of using transparent glass ceramics containing micron-sized SrF2 crystals for efficient 2.7 μm lasers and amplifiers.

  4. Analysis of Large Seeds from Three Different Medicago truncatula Ecotypes Reveals a Potential Role of Hormonal Balance in Final Size Determination of Legume Grains

    Directory of Open Access Journals (Sweden)

    Kaustav Bandyopadhyay

    2016-09-01

    Full Text Available Legume seeds are important as protein and oil source for human diet. Understanding how their final seed size is determined is crucial to improve crop yield. In this study, we analyzed seed development of three accessions of the model legume, Medicago truncatula, displaying contrasted seed size. By comparing two large seed accessions to the reference accession A17, we described mechanisms associated with large seed size determination and potential factors modulating the final seed size. We observed that early events during embryogenesis had a major impact on final seed size and a delayed heart stage embryo development resulted to large seeds. We also observed that the difference in seed growth rate was mainly due to a difference in embryo cell number, implicating a role of cell division rate. Large seed accessions could be explained by an extended period of cell division due to a longer embryogenesis phase. According to our observations and recent reports, we observed that auxin (IAA and abscisic acid (ABA ratio could be a key determinant of cell division regulation at the end of embryogenesis. Overall, our study highlights that timing of events occurring during early seed development play decisive role for final seed size determination.

  5. Analysis of Large Seeds from Three Different Medicago truncatula Ecotypes Reveals a Potential Role of Hormonal Balance in Final Size Determination of Legume Grains

    Science.gov (United States)

    Bandyopadhyay, Kaustav; Uluçay, Orhan; Şakiroğlu, Muhammet; Udvardi, Michael K.; Verdier, Jerome

    2016-01-01

    Legume seeds are important as protein and oil source for human diet. Understanding how their final seed size is determined is crucial to improve crop yield. In this study, we analyzed seed development of three accessions of the model legume, Medicago truncatula, displaying contrasted seed size. By comparing two large seed accessions to the reference accession A17, we described mechanisms associated with large seed size determination and potential factors modulating the final seed size. We observed that early events during embryogenesis had a major impact on final seed size and a delayed heart stage embryo development resulted to large seeds. We also observed that the difference in seed growth rate was mainly due to a difference in embryo cell number, implicating a role of cell division rate. Large seed accessions could be explained by an extended period of cell division due to a longer embryogenesis phase. According to our observations and recent reports, we observed that auxin (IAA) and abscisic acid (ABA) ratio could be a key determinant of cell division regulation at the end of embryogenesis. Overall, our study highlights that timing of events occurring during early seed development play decisive role for final seed size determination. PMID:27618017

  6. The contraction of granules of nanoporous super-cross-linked polystyrene sorbents as a result of the exclusion of large-sized mineral electrolyte ions from the polymer phase

    Science.gov (United States)

    Pastukhov, A. V.; Davankov, V. A.; Tsyurupa, M. P.; Blinnikova, Z. K.; Kavalerskaya, N. E.

    2009-03-01

    The deformation of neutral super-cross-linked polystyrene sorbents and ionites based on styrene-divinylbenzene gel-type copolymers brought in contact with concentrated solutions of HCl, H3PO4, NaOH, NH4Cl, (NH4)2SO4, and LiCl electrolytes was studied by dilatometry for separate spherical granules. Considerable contraction of super-cross-linked polystyrene matrices swollen in water was observed in concentrated solutions containing large-sized lithium, sulfate, and phosphate ions. Volume compressive strain correlated with the size of excluded hydrated ions. The contraction effect was caused by the difference in the osmotic pressure of water in thin pores and water in concentrated solutions filling large pores. The exclusion effect ignored earlier should also influence the degree of ion exchange and volume deformation of standard ion-exchange resins brought in contact with solutions of various electrolytes.

  7. Settling velocities in batch sedimentation. [Mixtures containing one and two sizes of resin beads, 44 and 62. mu. m in diameter

    Energy Technology Data Exchange (ETDEWEB)

    Fricke, A.M.; Thompson, B.E.

    1982-10-01

    The sedimentation of mixtures containing one and two sizes of spherical particles (44 and 62 ..mu..m in diameter) was studied. Radioactive tracing with /sup 57/Co was used to measure the settling velocities. The ratio of the settling velocity U of uniformly sized particles to the velocity predicted to Stokes' law U/sub 0/ was correlated to an expression of the form U/U/sub 0/ = epsilon/sup ..cap alpha../, where epsilon is the liquid volume fraction and ..cap alpha.. is an empirical constant, determined experimentally to be 4.85. No effect of viscosity on the ratio U/U/sub 0/ was observed as the viscosity of the liquid medium was varied from 1x10/sup -3/ to 5x10/sup -3/ Pa.s. The settling velocities of particles in a bimodal mixture were fit by the same correlation; the ratio U/U/sub 0/ was independent of the concentrations of different-sized particles.

  8. Influence of apheresis container size on the maintenance of platelet in vitro storage properties after a 30-h interruption of agitation.

    Science.gov (United States)

    Wagner, Stephen J; Skripchenko, Andrey; Seetharaman, Shalini; Myrup, Andrew; Kurtz, James; Thomas-Montgomery, Dedeene; Awatefe, Helen; Moroff, Gary

    2010-08-01

    We have previously conducted studies investigating maintenance of apheresis platelet in vitro quality measures during storage under simulated shipping conditions in which agitation was interrupted. This study examines the effect of increasing bag surface area on the preservation of in vitro platelet properties during storage with continuous agitation and with a 30 h interruption of agitation. Apheresis platelets were collected in 100% plasma with the Amicus separator to provide two identical platelet products, each with approximately 4-5 x 10(11) platelets. After collection, the volume was divided equally between 1.0 and 1.3 L PL2410 containers. In an initial study, both products were continuously agitated. In a second study, both products were subjected to a single 30-h period of interrupted agitation between Days 2 and 3 of storage by placement in a standard shipping box at room temperature. In each study, units were assayed during storage for standard in vitro platelet quality measures. Platelets stored in the 1.3 L container maintained slightly greater mean pH during 7 day storage with either continuous agitation (n=6) or with a 30-h interruption of agitation (n=12) than those of similarly treated identical platelets stored in the 1.0 L container. Most noteworthy, in experiments with products stored in the 1.0 L container in which there was a large decrease in pH to levels container was substantially greater (0.17+/-06 and 0.37+/-0.09 pH units greater, n=4, respectively). Other measures showed either small differences or comparability of platelet in vitro parameters with storage in the two containers after an interruption of agitation.

  9. The effect of multiple particle sizes on cooling rates of chondrules produced in large-scale shocks in the solar nebula

    CERN Document Server

    Morris, Melissa A; Desch, Steven J

    2016-01-01

    Chondrules represent one of the best probes of the physical conditions and processes acting in the early solar nebula. Proposed chondrule formation models are assessed based on their ability to match the meteoritic evidence, especially experimental constraints on their thermal histories. The model most consistent with chondrule thermal histories is passage through shock waves in the solar nebula. Existing models of heating by shocks generally yield a good first-order approximation to inferred chondrule cooling rates. However, they predict prolonged heating in the pre-shock region, which would cause volatile loss and isotopic fractionation, which are not observed. These models have typically included particles of a single (large) size, i.e., chondrule precursors, or at most, large particles accompanied by micron-sized grains. The size distribution of solids present during chondrule formation controls the opacity of the affected region, and significantly affects the thermal histories of chondrules. Micron-sized...

  10. Interspecies avian brain chimeras reveal that large brain size differences are influenced by cell-interdependent processes.

    Science.gov (United States)

    Chen, Chun-Chun; Balaban, Evan; Jarvis, Erich D

    2012-01-01

    Like humans, birds that exhibit vocal learning have relatively delayed telencephalon maturation, resulting in a disproportionately smaller brain prenatally but enlarged telencephalon in adulthood relative to vocal non-learning birds. To determine if this size difference results from evolutionary changes in cell-autonomous or cell-interdependent developmental processes, we transplanted telencephala from zebra finch donors (a vocal-learning species) into Japanese quail hosts (a vocal non-learning species) during the early neural tube stage (day 2 of incubation), and harvested the chimeras at later embryonic stages (between 9-12 days of incubation). The donor and host tissues fused well with each other, with known major fiber pathways connecting the zebra finch and quail parts of the brain. However, the overall sizes of chimeric finch telencephala were larger than non-transplanted finch telencephala at the same developmental stages, even though the proportional sizes of telencephalic subregions and fiber tracts were similar to normal finches. There were no significant changes in the size of chimeric quail host midbrains, even though they were innervated by the physically smaller zebra finch brain, including the smaller retinae of the finch eyes. Chimeric zebra finch telencephala had a decreased cell density relative to normal finches. However, cell nucleus size differences between each species were maintained as in normal birds. These results suggest that telencephalic size development is partially cell-interdependent, and that the mechanisms controlling the size of different brain regions may be functionally independent.

  11. Interspecies avian brain chimeras reveal that large brain size differences are influenced by cell-interdependent processes.

    Directory of Open Access Journals (Sweden)

    Chun-Chun Chen

    Full Text Available Like humans, birds that exhibit vocal learning have relatively delayed telencephalon maturation, resulting in a disproportionately smaller brain prenatally but enlarged telencephalon in adulthood relative to vocal non-learning birds. To determine if this size difference results from evolutionary changes in cell-autonomous or cell-interdependent developmental processes, we transplanted telencephala from zebra finch donors (a vocal-learning species into Japanese quail hosts (a vocal non-learning species during the early neural tube stage (day 2 of incubation, and harvested the chimeras at later embryonic stages (between 9-12 days of incubation. The donor and host tissues fused well with each other, with known major fiber pathways connecting the zebra finch and quail parts of the brain. However, the overall sizes of chimeric finch telencephala were larger than non-transplanted finch telencephala at the same developmental stages, even though the proportional sizes of telencephalic subregions and fiber tracts were similar to normal finches. There were no significant changes in the size of chimeric quail host midbrains, even though they were innervated by the physically smaller zebra finch brain, including the smaller retinae of the finch eyes. Chimeric zebra finch telencephala had a decreased cell density relative to normal finches. However, cell nucleus size differences between each species were maintained as in normal birds. These results suggest that telencephalic size development is partially cell-interdependent, and that the mechanisms controlling the size of different brain regions may be functionally independent.

  12. Flyby of Large-Size Space Debris Objects Situated at Leo with Their Successive De-Orbiting

    Directory of Open Access Journals (Sweden)

    A. A. Baranov

    2016-01-01

    Full Text Available Regarding the large-size space debris objects with a cross-section more than 5 m2 situated at LEO, it is possible to mark out 5 non-structured groups of such objects according to their spatial distribution. The orbits of objects in a group have approximately the same inclinations whereas the deviations in the Right Ascension of the Ascending node (RAAN may be arbitrary. The features of changing orbital planes’ mutual orientation in a group are seen from the RAAN deviations’ evolution portrait. The flights between the objects are being executed by a single active space vehicle (SV which captures a LSSD object and takes it away to the especially calculated circular or elliptical low disposal orbit (DO, and then returns back for the next object.The calculation of flyby maneuvers, in fact, breaks up into two independent tasks. At first, one can determine the parameters of the DO for each LSSD object using special software, so the coplanar maneuvers can be calculated ensuring the object’s transition to this orbit. Secondly, the flight to attain a new object is carried out from the DO of the previous object at the moment when their orbital planes will become equal. So it is possible to calculate the maneuvers, which help to return back for the next object, using numerical-analytical algorithm developed for noncoplanar rendez-vous of middle duration.The time interval for an active SV to stay at the DO is defined by difference of precession velocities of orbital planes of the de-orbited object and of the next object. The usage of a circular DO allows an LSSD object to leave promptly from the region (over 700 km where active SVs and other debris exist for a long time, whereas the apogee of the elliptical DO remains in the mentioned belt for 10 years. While forming elliptical DO one will need approximately 30% less of required summary characteristic velocity as compared with circular DO. The collision risk for an object staying at the elliptical DO

  13. Superficially porous particles with 1000Å pores for large biomolecule high performance liquid chromatography and polymer size exclusion chromatography.

    Science.gov (United States)

    Wagner, Brian M; Schuster, Stephanie A; Boyes, Barry E; Shields, Taylor J; Miles, William L; Haynes, Mark J; Moran, Robert E; Kirkland, Joseph J; Schure, Mark R

    2017-03-17

    To facilitate mass transport and column efficiency, solutes must have free access to particle pores to facilitate interactions with the stationary phase. To ensure this feature, particles should be used for HPLC separations which have pores sufficiently large to accommodate the solute without restricted diffusion. This paper describes the design and properties of superficially porous (also called Fused-Core(®), core shell or porous shell) particles with very large (1000Å) pores specifically developed for separating very large biomolecules and polymers. Separations of DNA fragments, monoclonal antibodies, large proteins and large polystyrene standards are used to illustrate the utility of these particles for efficient, high-resolution applications.

  14. Achieving high dielectric constant and low loss property in a dipolar glass polymer containing strongly dipolar and small-sized sulfone groups.

    Science.gov (United States)

    Wei, Junji; Zhang, Zhongbo; Tseng, Jung-Kai; Treufeld, Imre; Liu, Xiaobo; Litt, Morton H; Zhu, Lei

    2015-03-11

    In this report, a dipolar glass polymer, poly(2-(methylsulfonyl)ethyl methacrylate) (PMSEMA), was synthesized by free radical polymerization of the corresponding methacrylate monomer. Due to the large dipole moment (4.25 D) and small size of the side-chain sulfone groups, PMSEMA exhibited a strong γ transition at a temperature as low as -110 °C at 1 Hz, about 220 °C below its glass transition temperature around 109 °C. Because of this strong γ dipole relaxation, the glassy PMSEMA sample exhibited a high dielectric constant of 11.4 and a low dissipation factor (tan δ) of 0.02 at 25 °C and 1 Hz. From an electric displacement-electric field (D-E) loop study, PMSEMA demonstrated a high discharge energy density of 4.54 J/cm(3) at 283 MV/m, nearly 3 times that of an analogue polymer, poly(methyl methacrylate) (PMMA). However, the hysteresis loss was only 1/3-1/2 of that for PMMA. This study suggests that dipolar glass polymers with large dipole moments and small-sized dipolar side groups are promising candidates for high energy density and low loss dielectric applications.

  15. CONDENSED MATTER: ELECTRONIC STRUCTURE, ELECTRICAL, MAGNETIC, AND OPTICAL PROPERTIES: Enhanced Laser Cooling of Rare-Earth-Ion-Doped Glass Containing Nanometer-Sized Metallic Particles

    Science.gov (United States)

    Jia, You-Hua; Zhong, Biao; Yin, Jian-Ping

    2009-03-01

    The enhanced laser cooling performance of rare-earth-ions-doped glasses containing small particles is predicted. This is achieved by the enhancement of local field around rare earth ions, owing to the surface plasmon resonance of small metallic particles. The role of energy transfer between ions and the particle is theoretical discussed. Depending on the particle size and the ion emission quantum efficiency, the enhancement of the absorption and the fluorescence is predicted. Moreover, taking Yb3+ -doped ZBLAN as example, the cooling power and heat-light converting efficiency are calculated. It is finally concluded that the absorption and the fluorescence are greatly enhanced in these composite materials, the cooling power is increased compared to the bulk material.

  16. Quantification of population sizes of large herbivores and their long-term functional role in ecosystems using dung fungal spores

    NARCIS (Netherlands)

    Baker, Ambroise G.; Cornelissen, Perry; Bhagwat, Shonil A.; Vera, Fransciscus W M; Willis, Katherine J.

    2016-01-01

    The relationship between large herbivore numbers and landscape cover over time is poorly understood. There are two schools of thought: one views large herbivores as relatively passive elements upon the landscape and the other as ecosystem engineers driving vegetation succession. The latter relations

  17. Fabrication and optical characterization of large scale membrane containing InP/AlGaInP quantum dots

    Science.gov (United States)

    Niederbracht, H.; Hargart, F.; Schwartz, M.; Koroknay, E.; Kessler, C. A.; Jetter, M.; Michler, P.

    2015-06-01

    Single-photon sources with a high extraction efficiency are a prerequisite for applications in quantum communication and quantum computation schemes. One promising approach is the fabrication of a quantum dot containing membrane structure in combination with a solid immersion lens and a metal mirror. We have fabricated an 80 nm thin semiconductor membrane with incorporated InP quantum dots in an AlGaInP double hetero barrier via complete substrate removal. In addition, a gold layer was deposited on one side of the membrane acting as a mirror. The optical characterization shows in detail that the unique properties of the quantum dots are preserved in the membrane structure.

  18. Approved quarantine treatment for Hessian fly (Diptera: Cecidomyiidae) in large-size bales and Hessian fly and cereal leaf beetle (Coleoptera: Chrysomelidae) control by bale compression

    Science.gov (United States)

    An approved quarantine treatment using bale compression (32 kg/sq cm of pressure) and phosphine fumigation (61 g/28.2 cu m) aluminum phosphide for 7 d at 20 degrees C) was determined to control Hessian fly, Mayetiola destructor (Say), in large-size, polypropylene fabric-wrapped bales exported from t...

  19. Voices from the Field: The Perceptions of Teachers and Principals on the Class Size Reduction Program in a Large Urban School District.

    Science.gov (United States)

    Munoz, Marco A.; Portes, Pedro R.

    A class size reduction (CSR) program was implemented in a large low-performing urban elementary school district. The CSR program helps schools improve student learning by hiring additional teachers so that children in the early elementary grades can attend smaller classes. This study used a participant-oriented evaluation model to examine the…

  20. Evidence from a Large Sample on the Effects of Group Size and Decision-Making Time on Performance in a Marketing Simulation Game

    Science.gov (United States)

    Treen, Emily; Atanasova, Christina; Pitt, Leyland; Johnson, Michael

    2016-01-01

    Marketing instructors using simulation games as a way of inducing some realism into a marketing course are faced with many dilemmas. Two important quandaries are the optimal size of groups and how much of the students' time should ideally be devoted to the game. Using evidence from a very large sample of teams playing a simulation game, the study…

  1. A 3D Sphere Culture System Containing Functional Polymers for Large-Scale Human Pluripotent Stem Cell Production

    Directory of Open Access Journals (Sweden)

    Tomomi G. Otsuji

    2014-05-01

    Full Text Available Utilizing human pluripotent stem cells (hPSCs in cell-based therapy and drug discovery requires large-scale cell production. However, scaling up conventional adherent cultures presents challenges of maintaining a uniform high quality at low cost. In this regard, suspension cultures are a viable alternative, because they are scalable and do not require adhesion surfaces. 3D culture systems such as bioreactors can be exploited for large-scale production. However, the limitations of current suspension culture methods include spontaneous fusion between cell aggregates and suboptimal passaging methods by dissociation and reaggregation. 3D culture systems that dynamically stir carrier beads or cell aggregates should be refined to reduce shearing forces that damage hPSCs. Here, we report a simple 3D sphere culture system that incorporates mechanical passaging and functional polymers. This setup resolves major problems associated with suspension culture methods and dynamic stirring systems and may be optimal for applications involving large-scale hPSC production.

  2. Polystyrene-block-poly(ethylene oxide) copolymers as templates for stacked, spherical large-mesopore silica coatings: dependence of silica pore size on the PS/PEO ratio.

    Science.gov (United States)

    Nisticò, Roberto; Magnacca, Giuliana; Jadhav, Sushilkumar A; Scalarone, Dominique

    2016-01-01

    Large-mesopore silica films with a narrow pore size distribution and high porosity have been obtained by a sol-gel reaction of a silicon oxide precursor (TEOS) and using polystyrene-block-poly(ethylene oxide) (PS-b-PEO) copolymers as templates in an acidic environment. PS-b-PEO copolymers with different molecular weight and composition have been studied in order to assess the effects of the block length on the pore size of the templated silica films. The changes in the morphology of the porous systems have been investigated by transmission electron microscopy and a systematic analysis has been carried out, evidencing the dependence between the hydrophilic/hydrophobic ratio of the two polymer blocks and the size of the final silica pores. The obtained results prove that by tuning the PS/PEO ratio, the pore size of the templated silica films can be easily and finely predicted.

  3. Technology of large-sized heat-insulating elements for energetic redevelopment of facades; Grosselement-Daemmtechnik (GeDt) zur energetischen Fassadensanierung

    Energy Technology Data Exchange (ETDEWEB)

    Reyer, E. [Ingenieurgesellschaft Gathmann, Reyer, und Teilhaber mbH (IGRT), Bochum (Germany); Sieder, M. [Schweitzer GmbH - Beratende Ingenieure, Saarbrucken (Germany); Bamberger, C.; Schild, K. [Bochum Univ., Bochum (Germany). Baukonstruktionen und Bauphysik; Voelkner, S. [Rockwool International A/S, Hedehusene (Denmark). Group Development and Application

    2004-07-01

    Sustainable reduction of heating energy - required for our buildings - can be reached by additional insulation of existing old building facades. Sometimes homeowners interest about the heat-insulating redevelopment of their building facades seemed to be quite small, because of longer construction times and restrictions by scaffolding, noise and pollution often concerned with conventional technologies. New impulses for the realization of additional redevelopment measures can be given by innovative, time-saving and less disturbing redevelopment technologies - like the following described. So the federal ministry for economy and technology and 4 industry partners promoted the research project 'Energetic redevelopment of facades with industrial prefabrication technologies' at the University of Bochum (Institute of constructional civil engineering). In the context of this research project all essentials of the technology of large-sized heat-insulating elements for sustainable heating energy saving redevelopment of facades were developed. This technology is based on large-sized heat-insulating elements (height of about 2,80 m and length up to 8 m) considering aspects of structural analysis, physics relating to construction and assembling elements. For the application of the large-sized elements at building facades two fixing systems were created and tested - one based on dot-shaped fixings, the other on bar-shaped fixings. To ensure the prefabrication of those large-sized redevelopment elements and their exact assembling the development of a contactless surveying and marking out system was necessary - separately realized at the University of Bochum (area of geodetics). Large size and system-specific implementation details of the redevelopment elements mentioned above caused the development of suitable tools for assembling and transporting elements. (orig.)

  4. Analyses of large scale tests addressing the performance of a containment cooler and its effect on gas distribution

    Energy Technology Data Exchange (ETDEWEB)

    Andreani, M.; Mignot, G. [Paul Scherrer Inst., Villigen (Switzerland)

    2011-07-01

    The performance of containment coolers and their effect on the hydrogen risk in the case of an accident with core overheat is an issue that needs to be addressed by means of simulation tools. Four tests performed in the PANDA facility within the OECD SETH 2 project provide a new database to evaluate the capability of the codes to predict the cooling effectiveness of a cooler and its effect on flow patterns and light gas distribution. All tests have been simulated with the GOTHIC code using a three-dimensional mesh and a rather detailed model for the cooler tube bundle. In general, the results obtained are in reasonable agreement with the data, although some major discrepancies have also been observed, which are mostly due to the limited detail permitted by the relatively coarse mesh adopted for all tests of the SETH 2 project. (author)

  5. Do sex, body size and reproductive condition influence the thermal preferences of a large lizard? A study in Tupinambis merianae.

    Science.gov (United States)

    Cecchetto, Nicolas Rodolfo; Naretto, Sergio

    2015-10-01

    Body temperature is a key factor in physiological processes, influencing lizard performances; and life history traits are expected to generate variability of thermal preferences in different individuals. Gender, body size and reproductive condition may impose specific requirements on preferred body temperatures. If these three factors have different physiological functions and thermal requirements, then the preferred temperature may represent a compromise that optimizes these physiological functions. Therefore, the body temperatures that lizards select in a controlled environment may reflect a temperature that maximizes their physiological needs. The tegu lizard Tupinambis merianae is one of the largest lizards in South America and has wide ontogenetic variation in body size and sexual dimorphism. In the present study we evaluate intraspecific variability of thermal preferences of T. merianae. We determined the selected body temperature and the rate at which males and females attain their selected temperature, in relation to body size and reproductive condition. We also compared the behavior in the thermal gradient between males and females and between reproductive condition of individuals. Our study show that T. merianae selected body temperature within a narrow range of temperatures variation in the laboratory thermal gradient, with 36.24±1.49°C being the preferred temperature. We observed no significant differences between sex, body size and reproductive condition in thermal preferences. Accordingly, we suggest that the evaluated categories of T. merianae have similar thermal requirements. Males showed higher rates to obtain heat than females and reproductive females, higher rates than non-reproductive ones females. Moreover, males and reproductive females showed a more dynamic behavior in the thermal gradient. Therefore, even though they achieve the same selected temperature, they do it differentially.

  6. Refractory Inclusion Size Distribution and Fabric Measured in a Large Slab of the Allende CV3 Chondrite

    Science.gov (United States)

    Srinivasan, P.; Simon, Justin I.; Cuzzi, J. N.

    2013-01-01

    Aggregate textures of chondrites reflect accretion of early-formed particles in the solar nebula. Explanations for the size and density variations of particle populations found among chondrites are debated. Differences could have risen out of formation in different locations in the nebula, and/or they could have been caused by a sorting process [1]. Many ideas on the cause of chondrule sorting have been proposed; some including sorting by mass [2,3], by X-winds [4], turbulent concentration [5], and by photophoresis [6]. However, few similar studies have been conducted for Ca-, Al-rich inclusions (CAIs). These particles are known to have formed early, and their distribution could attest to the early stages of Solar System (ESS) history. Unfortunately, CAIs are not as common in chondrites as chondrules are, reducing the usefulness of studies restricted to a few thin sections. Furthermore, the largest sizes of CAIs are generally much larger than chondrules, and therefore rarely present in most studied chondrite thin sections. This study attempts to perform a more representative sampling of the CAI population in the Allende chondrite by investigating a two decimeter-sized slab.

  7. [Hepatoma 27 cells and the epithelium of the large intestine in rats contain the identical set of prekeratin proteins].

    Science.gov (United States)

    Troianovskiĭ, S M; Krutovskikh, V A; Bannikov, G A

    1984-08-01

    It has been shown by means of the immunoblot technique in combination with monoclonal antibodies and peptide mapping that hepatocytes, hepatoma 27 cells, and rat colon enterocytes exhibit a common prekeratin protein with a molecular weight of 49 kD (PK49). This protein and vimentin, a protein contained by intermediate filaments of mesenchymal cells, share at least one antigenic determinant. The generally accepted procedure for prekeratin purification leads to a more or less pronounced degradation of PK49. The degree of degradation is dependent on the type of the tissue extracted. High heterogenicity of prekeratin polypeptides described elsewhere might be due partly to such a degradation process. In addition to PK49, hepatoma 27 cells, absorbing, goblet and proliferating cells of the colon demonstrated three more prekeratin proteins: two major (PK55 and PK40) and one minor (PK53). Monoclonal antibodies not reacting with PK49 do not recognize PK55, PK53 and PK40. PK55, PK49 and PK40 of hepatoma 27 are identical to the appropriate proteins of the colonic epithelium as judged by peptide mapping. Thus, the cells of the hepatocyte origin are able to synthesize the same prekeratins as the colonic epithelium.

  8. A comparative toxicity study between small and large size zinc oxide nanoparticles in tilapia (Oreochromis niloticus): Organ pathologies, osmoregulatory responses and immunological parameters.

    Science.gov (United States)

    Kaya, Hasan; Aydın, Fatih; Gürkan, Mert; Yılmaz, Sevdan; Ates, Mehmet; Demir, Veysel; Arslan, Zikri

    2016-02-01

    Tilapia (Oreochromis niloticus) was exposed to different sizes of zinc oxide nanoparticles (ZnO-NPs) to evaluate their organ pathologies (kidney, liver, gill, and intestine), osmoregulatory responses and immunological parameters. Sub-chronic exposure was conducted in fresh water with 1 and 10 mg/L concentrations of the small (10-30 nm) and large-size ZnO (100 nm) particles for 7 and 14 days. In this study, it is found that small and large forms of ZnO-NPs cause various pathologic findings in the target organs at all concentrations. These findings are increased of melanomacrophage aggregates, tubular deformations, necrosis and cytoplasmic vacuolations in the kidney, oedema, mononuclear cell infiltrations, fatty changes, pyknotic nuclei and hepatocellular vacuolations in the liver, hyperplasia, aneurysms, and epithelial liftings in the gills, and hyperplasia, swelled of goblet cells, villus deformations in the intestine. Results showed that respiratory burst and potential killing activity at the small-size ZnO concentration significantly increased compared to the control group (p < 0.05) but significant reductions of these parameters at the large-size ZnO concentrations compared to control (p < 0.05) were measured. These findings demonstrate the potential of each particle size to cause significant damage to the immune system. Moreover, because ZnO NPs inhibit the Na(+), K(+)-ATPase activity at all concentrations and increase serum Ca(2+) and Cl(-) levels especially in gill, these particles are osmoregulatory and toxicant for tilapia fish. As a summary, both sizes of the particles have led to organ damage, osmoregulatory changes and immune disorder in tilapia fish.

  9. Polystyrene-block-poly(ethylene oxide) copolymers as templates for stacked, spherical large-mesopore silica coatings: dependence of silica pore size on the PS/PEO ratio

    OpenAIRE

    2016-01-01

    Large-mesopore silica films with a narrow pore size distribution and high porosity have been obtained by a sol–gel reaction of a silicon oxide precursor (TEOS) and using polystyrene-block-poly(ethylene oxide) (PS-b-PEO) copolymers as templates in an acidic environment. PS-b-PEO copolymers with different molecular weight and composition have been studied in order to assess the effects of the block length on the pore size of the templated silica films. The changes in the morphology of the porou...

  10. Hydroelastic response of 19,000 TEU class ultra large container ship with novel mobile deckhouse for maximizing cargo capacity

    Directory of Open Access Journals (Sweden)

    Hong-Il Im

    2017-05-01

    Full Text Available This paper is related to structural design evaluation of 19,000 TEU ultra large container ship, dealing with hydroelastic response, i.e. springing and whipping. It illustrates application of direct calculation tools and methodologies to both fatigue and ultimate strength assessment, simultaneously taking into account ship motions and her elastic deformations. Methodology for springing and whipping assessment within so called WhiSp notation is elaborated in details, and in order to evaluate innovative container ship design with increased loading capacity, a series of independent hydroelastic computations for container ship with mobile deckhouse and conventional one are performed with the same calculation setup. Fully coupled 3D FEM – 3D BEM model is applied, while the ultimate bending capacity of hull girder is determined by means of MARS software. Beside comparative analysis of representative quantities for considered ships, relative influence of hydroelasticity on ship response is addressed.

  11. Sizing and Siting of Large-Scale Batteries in Transmission Grids to Optimize the Use of Renewables

    NARCIS (Netherlands)

    Fiorini, Laura; Pagani, Giuliano; Pelacchi, P.; Poli, Davide; Aiello, Marco

    2017-01-01

    Power systems are a recent field of application of Complex Network research, which allows to perform large scale studies and evaluations. Based on this theory, a power grid is modeled as a weighted graph with several kinds of nodes and edges, and further analysis can help in investigating the behavi

  12. Large-scale HI in nearby radio galaxies : segregation in neutral gas content with radio source size

    NARCIS (Netherlands)

    Emonts, B. H. C.; Morganti, R.; Oosterloo, T. A.; van der Hulst, J. M.; van Moorsel, G.; Tadhunter, C. N.

    2007-01-01

    We present results of a study of neutral hydrogen ( HI) in a complete sample of nearby non-cluster radio galaxies. We find that radio galaxies with large amounts of extended HI (M-HI >= 109 M-circle dot) all have a compact radio source. The host galaxies of the more extended radio sources, all of Fa

  13. Secondary craters from large impacts on Europa and Ganymede: Ejecta size-velocity distributions on icy worlds, and the scaling of ejected blocks

    Science.gov (United States)

    Singer, Kelsi N.; McKinnon, William B.; Nowicki, L. T.

    2013-09-01

    We have mapped fields of secondary craters around three large primary craters on Europa and Ganymede and estimated the size and velocity of the fragments that formed the secondaries using updated scaling equations for ice impacts. We characterize the upper envelope of the fragment size-velocity distribution to obtain a function for the largest fragments at a given ejection velocity. Power-law velocity exponents found in our study of icy satellite secondary fields are compared to the exponents found for similar studies of mercurian, lunar, and martian craters; for all but basin-scale impacts, fragment size decreases more slowly with increasing ejection velocity than on rocky bodies. Spallation theory provides estimates of the size of ejected spall plates at a given velocity, but this theory predicts fragments considerably smaller than are necessary to form most of our observed secondaries. In general, ejecta fragment sizes scale with primary crater diameter and decrease with increasing ejection velocity, υej, by 1/υej or greater, and point-source scaling implies a relation between the two. The largest crater represented in any of these studies, Gilgamesh on Ganymede, exhibits a relatively steep velocity dependence. Extrapolating the results to the escape speed for each icy moon yields the size of the largest fragment that could later re-impact to form a so-called sesquinary crater, either on the parent moon or a neighboring satellite. We find that craters above 2 km in diameter on Europa and Ganymede are unlikely to be sesquinaries.

  14. Performance of a large size triple GEM detector at high particle rate for CBM Experiment at FAIR

    CERN Document Server

    Adak, Rama Prasad; Dubey, A K; Samanta, Subhasis; Saini, J; Das, S; Raha, S; Chattopadhyay, Subhasis

    2016-01-01

    In CBM experiment dimuon will be detected by a Muon Chamber (MUCH) consisting of segmented absorbers of varying widths and of tracking chambers sandwiched between the absorber-pairs. In this fixed target experiment operating at the highest interaction rate of $~10~MHz$, the first tracking chamber in its inner radial ring will face a particle rate of $400 kHz/cm^2$. To operate at such a high particle density, GEM technology based detectors have been chosen for the first two stations of MUCH. We have reported earlier the performance of several small-size GEM detector prototypes built at VECC for use in MUCH. A real-size GEM prototype has been tested using proton beam of momentum $2.36 ~GeV/c$ at COSY- Juelich, Germany. The detector was read out using nXYTER ASIC operated in self-triggering mode. An efficiency of the detector higher than $96\\%$ has been achieved. Variation of efficiency with the rate of incoming protons when tested at the highest rate of 1.5 MHz/cm$^2$ has been found to vary within $~2\\%$. The g...

  15. Efficient algorithm for locating and sizing series compensation devices in large power transmission grids: II. Solutions and applications

    Science.gov (United States)

    Frolov, Vladimir; Backhaus, Scott; Chertkov, Misha

    2014-10-01

    In a companion manuscript (Frolov et al 2014 New J. Phys. 16 art. no.) , we developed a novel optimization method for the placement, sizing, and operation of flexible alternating current transmission system (FACTS) devices to relieve transmission network congestion. Specifically, we addressed FACTS that provide series compensation (SC) via modification of line inductance. In this sequel manuscript, this heuristic algorithm and its solutions are explored on a number of test cases: a 30-bus test network and a realistically-sized model of the Polish grid (˜2700 nodes and ˜3300 lines). The results from the 30-bus network are used to study the general properties of the solutions, including nonlocality and sparsity. The Polish grid is used to demonstrate the computational efficiency of the heuristics that leverage sequential linearization of power flow constraints, and cutting plane methods that take advantage of the sparse nature of the SC placement solutions. Using these approaches, we can use the algorithm to solve a Polish transmission grid in tens of seconds. We explore the utility of the algorithm by analyzing transmission networks congested by (i) uniform load growth, (ii) multiple overloaded configurations, and (iii) sequential generator retirements.

  16. Efficient Algorithm for Locating and Sizing Series Compensation Devices in Large Transmission Grids: Solutions and Applications (PART II)

    Energy Technology Data Exchange (ETDEWEB)

    Frolov, Vladimir [Moscow Inst. of Physics and Technology (MIPT), Moscow (Russian Federation); Backhaus, Scott N. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Chertkov, Michael [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-01-14

    In a companion manuscript, we developed a novel optimization method for placement, sizing, and operation of Flexible Alternating Current Transmission System (FACTS) devices to relieve transmission network congestion. Specifically, we addressed FACTS that provide Series Compensation (SC) via modification of line inductance. In this manuscript, this heuristic algorithm and its solutions are explored on a number of test cases: a 30-bus test network and a realistically-sized model of the Polish grid (~2700 nodes and ~3300 lines). The results on the 30-bus network are used to study the general properties of the solutions including non-locality and sparsity. The Polish grid is used as a demonstration of the computational efficiency of the heuristics that leverages sequential linearization of power flow constraints and cutting plane methods that take advantage of the sparse nature of the SC placement solutions. Using these approaches, the algorithm is able to solve an instance of Polish grid in tens of seconds. We explore the utility of the algorithm by analyzing transmission networks congested by (a) uniform load growth, (b) multiple overloaded configurations, and (c) sequential generator retirements

  17. Clinical outcomes of EUS-guided drainage of debris-containing pancreatic pseudocysts: a large multicenter study

    Science.gov (United States)

    Yang, Dennis; Amin, Sunil; Gonzalez, Susana; Mullady, Daniel; Edmundowicz, Steven A.; DeWitt, John M.; Khashab, Mouen A.; Wang, Andrew Y.; Nagula, Satish; Buscaglia, Jonathan M.; Bucobo, Juan Carlos; Wagh, Mihir S.; Draganov, Peter V.; Stevens, Tyler; Vargo, John J.; Khara, Harshit S.; Diehl, David L.; Keswani, Rajesh N.; Komanduri, Srinadh; Yachimski, Patrick S.; Prabhu, Anoop; Kwon, Richard S.; Watson, Rabindra R.; Goodman, Adam J.; Benias, Petros; Carr-Locke, David L.; DiMaio, Christopher J.

    2017-01-01

    Background and study aims Data on clinical outcomes of endoscopic drainage of debris-free pseudocysts (PDF) versus pseudocysts containing solid debris (PSD) are very limited. The aims of this study were to compare treatment outcomes between patients with PDF vs. PSD undergoing endoscopic ultrasound (EUS)-guided drainage via transmural stents. Patients and methods Retrospective review of 142 consecutive patients with pseudocysts who underwent EUS-guided transmural drainage (TM) from 2008 to 2014 at 15 academic centers in the United States. Main outcome measures included TM technical success, treatment outcomes (symptomatic and radiologic resolution), need for endoscopic re-intervention at follow-up, and adverse events (AEs). Results TM was performed in 90 patients with PDF and 52 with PSD. Technical success: PDF 87 (96.7 %) vs. PSD 51 (98.1 %). There was no difference in the rates for endoscopic re-intervention (5.5 % in PDF vs. 11.5 % in PSD; P = 0.33) or AEs (12.2 % in PDF vs. 19.2 % in PSD; P = 0.33). Median long-term follow-up after stent removal was 297 days (interquartile range [IQR]: 59 – 424 days) for PDF and 326 days (IQR: 180 – 448 days) for PSD (P = 0.88). There was a higher rate of short-term radiologic resolution of PDF (45; 66.2 %) vs. PSD (21; 51.2 %) (OR = 0.30; 95 % CI: 0.13 – 0.72; P = 0.009). There was no difference in long-term symptomatic resolution (PDF: 70.4 % vs. PSD: 66.7 %; P = 0.72) or radiologic resolution (PDF: 68.9 % vs. PSD: 78.6 %; P = 0.72) Conclusions There was no difference in need for endoscopic re-intervention, AEs or long-term treatment outcomes in patients with PDF vs. PSD undergoing EUS-guided drainage with transmural stents. Based on these results, the presence of solid debris in pancreatic fluid collections does not appear to be associated with a poorer outcome. PMID:28210709

  18. Study on ion conductivity and crystallinity of composite polymer electrolytes based on poly(ethylene oxide)/poly(acrylonitrile) containing nano-sized Al2O3 fillers.

    Science.gov (United States)

    Kim, Mingyeong; Lee, Lyungyu; Jung, Yongju; Kim, Seok

    2013-12-01

    In this paper, composite polymer electrolytes were prepared by a blend of poly(ethylene oxide) (PEO) and poly(acrylonitrile) (PAN) as a polymer matrix, ethylene carbonate as a plasticizer, LiClO4 as a salt, and by containing a different content of nano-sized Al2O3. The composite films were prepared by using the solution casting method. The crystallinity and ionic conductivity of the polymer electrolytes was investigated using X-ray diffraction (XRD) and AC impedance method, respectively. The morphology of composite polymer electrolyte film was analyzed by SEM method. From the experimental results, by increasing the Al2O3 content, the crystallinity of PEO was reduced, and the ionic conductivity was increased. In particular, by a doping of 15 wt.% Al2O3 in PEO/PAN polymer blend, the CPEs showed the superior ionic conductivity. However, when Al2O3 content exceeds 15 wt.%, the ionic conductivity was decreased. From the surface morphology, it was concluded that the ionic conductivity was decreased because the CPEs showed a heterogenous morphology due to immiscibility or aggregation of the ceramic filler within the polymer matrix.

  19. Growth of large size diamond single crystals by plasma assisted chemical vapour deposition: Recent achievements and remaining challenges

    Science.gov (United States)

    Tallaire, Alexandre; Achard, Jocelyn; Silva, François; Brinza, Ovidiu; Gicquel, Alix

    2013-02-01

    Diamond is a material with outstanding properties making it particularly suited for high added-value applications such as optical windows, power electronics, radiation detection, quantum information, bio-sensing and many others. Tremendous progresses in its synthesis by microwave plasma assisted chemical vapour deposition have allowed obtaining single crystal optical-grade material with thicknesses of up to a few millimetres. However the requirements in terms of size, purity and crystalline quality are getting more and more difficult to achieve with respect to the forecasted applications, thus pushing the synthesis method to its scientific and technological limits. In this paper, after a short description of the operating principles of the growth technique, the challenges of increasing crystal dimensions both laterally and vertically, decreasing and controlling point and extended defects as well as modulating crystal conductivity by an efficient doping will be detailed before offering some insights into ways to overcome them.

  20. Amino acid alphabet size in protein evolution experiments: better to search a small library thoroughly or a large library sparsely?

    Science.gov (United States)

    Muñoz, Enrique; Deem, Michael W

    2008-05-01

    We compare the results obtained from searching a smaller library thoroughly versus searching a more diverse, larger library sparsely. We study protein evolution with reduced amino acid alphabets, by simulating directed evolution experiments at three different alphabet sizes: 20, 5 and 2. We employ a physical model for evolution, the generalized NK model, that has proved successful in modeling protein evolution, antibody evolution and T-cell selection. We find that antibodies with higher affinity are found by searching a library with a larger alphabet sparsely than by searching a smaller library thoroughly, even with well-designed reduced libraries. We also find ranked amino acid usage frequencies in agreement with observations of the CDR-H3 variable region of human antibodies.

  1. Preliminary approach on early post mortem stress and quality indexes changes in large size bluefin tuna (Thunnus thynnus

    Directory of Open Access Journals (Sweden)

    R. Ugolini

    2010-01-01

    Full Text Available Bluefin tuna (Thunnus thynnus is very appreciated on Japan and USA market for the preparation of sushi and sahimi. The market price of the fresh product can vary from 8 to 33 Euro/kg (gate farm/producers prices according to size, shape, fat level, meat colour, consistency and freshness (absence of “hyake”, all parameters strictly connected to feeding quality and quantity, rearing and killing stress factors and refrigeration times and conditions after death. Excessive levels of stress during the slaughtering can affect meat quality, contributing to significantly decrease of tuna’s price. The present trial was carried out to evaluate the possible harvesting/slaughtering stress effect on reared bluefin tuna meat quality, starting from the examination of the most important stress and quality parameters changes during the early post mortem period.

  2. Determining organic carbon distributions in soil particle size fractions as a precondition of lateral carbon transport modeling at large scales

    Science.gov (United States)

    Schindewolf, Marcus; Seher, Wiebke; Pfeffer, Eduard; Schultze, Nico; Amorim, Ricardo S. S.; Schmidt, Jürgen

    2016-04-01

    The erosional transport of organic carbon has an effect on the global carbon budget, however, it is uncertain, whether erosion is a sink or a source for carbon in the atmosphere. Continuous erosion leads to a massive loss of top soils including the loss of organic carbon historically accumulated in the soil humus fraction. The colluvial organic carbon could be protected from further degradation depending on the depth of the colluvial cover and local decomposing conditions. Another part of eroded soils and organic carbon will enter surface water bodies and might be transported over long distances. The selective nature of soil erosion results in a preferential transport of fine particles while less carbonic larger particles remain on site. Consequently organic carbon is enriched in the eroded sediment compared to the origin soil. As a precondition of process based lateral carbon flux modeling, carbon distribution on soil particle size fractions has to be known. In this regard the present study refers to the determination of organic carbon contents on soil particle size separates by a combined sieve-sedimentation method for different tropical and temperate soils Our results suggest high influences of parent material and climatic conditions on carbon distribution on soil particle separates. By applying these results in erosion modeling a test slope was simulated with the EROSION 2D simulation software covering certain land use and soil management scenarios referring to different rainfall events. These simulations allow first insights on carbon loss and depletion on sediment delivery areas as well as carbon gains and enrichments on deposition areas on the landscape scale and could be used as a step forward in landscape scaled carbon redistribution modeling.

  3. Is the large size of the pinna of the ear of the European hare (Lepus europaeus) due to its role in thermoregulation or in anterior capital shock absorption?

    Science.gov (United States)

    Stott, Philip; Jennings, Nancy; Harris, Stephen

    2010-06-01

    Large pinnae are characteristic of the Leporids, and the pinna is known to have a thermoregulatory role. Another role has been hypothesized for the pinna of Lepus spp., as a part of a suspensory system for the greater portion of the head, absorbing shock that might otherwise interfere with vision during high-speed locomotion. We compared the lengths of the pinnae of adult European hares Lepus europaeus from the source population in the cooler climate of England with those of the introduced population in the warmer climate of Australia, and we compared the lengths of the pinnae of hares that had grown in cooler weather with those that had grown in warmer weather. There were no significant differences between each of the comparisons, indicating that the size of the pinna is not determined by thermoregulatory requirements at rest. We compared the growth in length of the pinnae and the legs with growth in body mass, and growth in the mass of the pinnae with the masses of the head and the eyeballs, and found support for the suspension hypothesis. We suggest that the rapid growth of the pinna is because visual acuity is a function of absolute eye size, not relative eye size, yet juvenile hares are subject to the same predator pressure as adult hares, and equally need to maximize visual acuity while running at high speeds in dim light. We believe that the large size of the pinna is determined by its role in anterior capital suspension, not in thermoregulation.

  4. Large-sized hepotocellular carcinoma (HCC): a neoadjuvant treatment protocol with repetitive transarterial chemoembolization (TACE) before percutaneous MR-guided laser-induced thermotherapy (LITT)

    Energy Technology Data Exchange (ETDEWEB)

    Zangos, Stephan; Eichler, Katrin; Balzer, Joern O.; Straub, Ralf; Hammerstingl, Renate; Herzog, Christopher; Lehnert, Thomas; Heller, Mathias; Thalhammer, Axel; Mack, Martin G.; Vogl, Thomas J. [University Hospital Frankfurt, Johann Wolfgang Goethe-University, Department of Diagnostic and Interventional Radiology, Frankfurt/Main (Germany)

    2007-02-15

    This study aims to evaluate the efficacy and safety of a neoadjuvant treatment protocol with repeated transarterial chemoembolization (TACE) before MR-guided laser-induced thermotherapy (LITT) for large-sized hepatocellular carcinomas (HCC). Repeated TACE (mean, 3.5 treatments per patient) was performed in 48 patients with neoadjuvant intention (the largest lesion was between 50 and 80 mm in diameter, and there were no more than five lesions). For the TACE treatment, we used 10 mg/m{sup 2} mitomycin, 10 ml/m{sup 2} Lipiodol and microspheres. The tumor volume was measured by MRI. Lipiodol retention of the tumors was evaluated with CT. After the diameter of the tumors had decreased to less than 50 mm, the patients were treated with MR-guided LITT 4 to 6 weeks after embolization. Repeated TACE reduced the tumor size in 32 patients (66.7%), forming the basis for performing MR-guided LITT procedures. These patients received one to four laser treatments (mean, 1.9 per patient) for tumor ablation, resulting in a median survival of 36.0 months after the first treatment. For the remaining patients, no reduction in tumor size was achieved in 12 patients and disease progression in 4 patients. Neoadjuvant TACE appears to be an effective treatment of large-sized HCC, which extends the indication for MR-guided LITT. (orig.)

  5. Bayesian inference of genetic parameters on litter size and gestation length in Hungarian Landrace and Hungarian Large White pigs

    Directory of Open Access Journals (Sweden)

    Zoltán Csörnyei

    2010-01-01

    Full Text Available Genetic parameters of number of piglets born alive (NBA and gestation length (GL were analyzed for 39798 Hungarian Landrace (HLA, 141397 records and 70356 Hungarian Large White (HLW, 246961 records sows. Bivariate repeatability animal models were used, applying a Bayesian statistics. Estimated and heritabilitie repeatabilities (within brackets, were low for NBA, 0.07 (0.14 for HLA and 0.08 (0.17 for HLW, but somewhat higher for GL, 0.18 (0.27 for HLA and 0.26 (0.35 for HLW. Estimated genetic correlations between NBA and GL were low, -0.08 for HLA and -0.05 for HLW.

  6. Bayesian inference of genetic parameters on litter size and gestation length in Hungarian Landrace and Hungarian Large White pigs

    OpenAIRE

    Zoltán Csörnyei; László Csató; János Farkas; Ino Curik; István Nagy

    2010-01-01

    Genetic parameters of number of piglets born alive (NBA) and gestation length (GL) were analyzed for 39798 Hungarian Landrace (HLA, 141397 records) and 70356 Hungarian Large White (HLW, 246961 records) sows. Bivariate repeatability animal models were used, applying a Bayesian statistics. Estimated and heritabilitie repeatabilities (within brackets), were low for NBA, 0.07 (0.14) for HLA and 0.08 (0.17) for HLW, but somewhat higher for GL, 0.18 (0.27) for HLA and 0.26 (0.35) for HLW. Estimated...

  7. Global phylogeography of the dolphinfish (Coryphaena hippurus): the influence of large effective population size and recent dispersal on the divergence of a marine pelagic cosmopolitan species.

    Science.gov (United States)

    Díaz-Jaimes, P; Uribe-Alcocer, M; Rocha-Olivares, A; García-de-León, F J; Nortmoon, P; Durand, J D

    2010-12-01

    Pelagic fish that are distributed circumtropically are characterised by a low population structure level as a result of a high capacity for dispersion and large population sizes. Nevertheless, historical and contemporary processes, including past demographic and/or range expansions, secondary contact, dispersal, gene flow, and the achievement of large effective population sizes, may play a part in the detection of divergence signals, especially in the case of tropical pelagic species, whose distribution range depends strongly on the sea surface temperature. The connectivity and historical demography of Atlantic, Indian, Pacific and Mediterranean populations of dolphinfish (Coryphaena hippurus) was studied using partial sequences of the mitochondrial DNA NADH dehydrogenase subunit 1 (ND1). AMOVA analyses revealed significant inter-oceanic divergence with three phylogroups located in the Indo-Pacific, Eastern Atlantic, and Mediterranean Sea, the last one being the most divergent. However, it was not possible to clearly observe any genetic differentiation between the Indo-Pacific and Atlantic populations, as has been reported for most tropical pelagic species of tuna and billfishes. This supports the assumption of recent dispersal among basins facilitated by the actual continuous distribution of dolphinfish populations. Moreover, the lack of a divergence signal for populations separated by the Panamanian Isthmus reveals that genetic drift does not exert a strong influence on tropical pelagic species with large effective population sizes.

  8. Evolutionarily stable size of a megagametophyte: evolution of tiny megagametophytes of angiosperms from large ones of gymnosperms.

    Science.gov (United States)

    Sakai, Satoki

    2013-02-01

    To examine the factors favoring large megagametophytes of gymnosperms and tiny ones of angiosperms, a game model for seed production was developed in which megagametophytes growing in the same female parent compete for resources provided by the parent. In the model, megagametophytes may continue to grow until seed completion or may cease to grow at a certain time and regrow at pollination or fertilization. Autonomous abortion of unpollinated or unfertilized megagametophytes may occur either at pollination or fertilization. Those megagametophytes absorb a certain amount of resources before abortion, due to constraints in the signal process, in addition to the resources absorbed before pollination or fertilization. It was found that both growth habits can be the ESS: megagametophytes continue to grow without cessation and monopolize resources, such as gymnosperms, or cease to grow until fertilization to reduce the loss of resources due to autonomous abortion, such as angiosperms. The former and the latter are the ESS if the time interval between pollination and fertilization is long and short, respectively. Thus, the fertilization interval may be a critical factor selecting for large megagametophytes of gymnosperms or tiny ones of angiosperms.

  9. Technology of CCS coal utilization (outline of large-size demonstration test for CCS); CCS tan riyo gijutsu

    Energy Technology Data Exchange (ETDEWEB)

    Konno, K. [Center for Coal Utilization, Japan, Tokyo (Japan); Hironaka, H. [Idemitsu Kosan Co. Ltd., Tokyo (Japan)

    1996-09-01

    The coal cartridge system (CCS) is a series of the total system, in which coal is processed centrally at a supply base for each unit of consumer areas, supplied as pulverized coal in bulk units, and coal ash after combustion is recovered and treated. The system is expected of advantages resulted from the centralized production, elimination of handling troubles, and cleanliness. Following a small scale demonstration test, a large demonstration test for practically usable scale has begun in 1990, and completed in fiscal 1995. This paper introduces the CCS and reports the result of the test. In the large demonstration test, a supply station (with manufacturing capability of 200,000 tons a year) was installed in the Aichi refinery of Idemitsu Kosan Co., Ltd., and systematization on quality design and system technologies has been carried out. Long-term continuous operation for five years was achieved (operation time of the supply facilities was about 19,000 hours) without a failure and accident, to which every elemental technology was evaluated highly, and convenience and reliability of the system was verified. 13 figs., 3 tabs.

  10. Structural evolution of Ti destroyable interlayer in large-size diamond film deposition by DC arc plasma jet

    Science.gov (United States)

    Guo, Jianchao; Li, Chengming; Liu, Jinlong; Wei, Junjun; Chen, Liangxian; Hua, Chenyi; Yan, Xiongbo

    2016-05-01

    The addition of titanium (Ti) interlayer was verified to reduce the residual stress of diamond films by self-fracturing and facilitate the harvest of a crack-free free-standing diamond film prepared by direct current (DC) arc plasma jet. In this study, the evolution of the Ti interlayer between large-area diamond film and substrate was studied and modeled in detail. The evolution of the interlayer was found to be relevant to the distribution of the DC arc plasma, which can be divided into three areas (arc center, arc main, and arc edge). The formation rate of titanium carbide (TiC) in the arc main was faster than in the other two areas and resulted in the preferred generation of crack in the diamond film in the arc main during cooling. Sandwich structures were formed along with the growth of TiC until the complete transformation of the Ti interlayer. The interlayer released stress via self-fracture. Avoiding uneven fragile regions that formed locally in the interlayer and achieving cooperatively released stress are crucial for the preparation of large crack-free diamond films.

  11. Outcome of shock wave lithotripsy as monotherapy for large solitary renal stones (>2 cm in size without stenting

    Directory of Open Access Journals (Sweden)

    Shanmugasundaram Rajaian

    2010-01-01

    Full Text Available Purpose : To evaluate the outcome of shock wave lithotripsy (SWL as monotherapy for solitary renal stones larger than 2 cm without ureteral stenting. Materials and Methods : Our retrospective study included patients with solitary renal radio opaque stones larger than 2 cm treated with SWL using electromagnetic Dornier Compact S lithotripter device (Wessling, Germany for a period of 3 years (September 2002-2005. Stone clearance was assessed at 1 week, 1 month, and 3 months with plain X-rays of kidney, ureter, and bladder region, ultrasonography, and tomograms. Stone-free status, morbidity of the procedure, and fate of clinically insignificant residual fragments (CIRF were studied. A stone-free state was defined as no radiologic evidence of stone. Success was defined as complete clearance + CIRF. Results : Fifty-five patients, aged 11-65 years (mean 49.8 underwent SWL. Of them, only two were children. Male-to-female ratio was 3:1. The stone size was 21-28 mm (average 24 mm. The mean number of shocks were 3732 (range 724-12,100 and average energy level was 14 kV (range 11-16 kV. The mean follow-up was 18 months (range 3-22 months. Over all, stone-free status was achieved in 50% and success in 81% at 3 months. Stone clearance was not affected by stone location. Stones 26 mm (P = -0.10. Of 54 patients, 39 developed steinstrasse with mean length of 3.2 cm (range 1.4-6.2 cm and only four required intervention. Effectiveness quotient (EQ for SWL monotherapy for solitary renal stones more than 2 cm was 25.3%. The EQ for stones <25 mm and those more than 25 mm were 28.4% and 10% (P = -0.12, respectively. There was a lesser trend of difference between stones with size <25 and more than 25 mm. During the last review, the overall stone-free rate was 67.2%. Conclusions : SWL monotherapy was safe but significantly less effective for solitary renal stones larger than 2 cm. It can only be suggested to those who refuse surgical intervention. Pretreatment DJ

  12. γ-Fe{sub 2}O{sub 3} by sol–gel with large nanoparticles size for magnetic hyperthermia application

    Energy Technology Data Exchange (ETDEWEB)

    Lemine, O.M., E-mail: leminej@yahoo.com [Physics Department, College of Sciences, Al Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh (Saudi Arabia); Omri, K. [Laboratory of Physics of Materials and Nanomaterials Applied at Environment (LaPhyMNE), Faculty of Sciences in Gabes, Gabes (Tunisia); Iglesias, M.; Velasco, V. [Instituto de Magnetismo Aplicado, UCM-ADIF-CSIC (Spain); Crespo, P.; Presa, P. de la [Instituto de Magnetismo Aplicado, UCM-ADIF-CSIC (Spain); Dpto. Física de Materiales, Universidad Complutense de Madrid (Spain); El Mir, L. [Physics Department, College of Sciences, Al Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh (Saudi Arabia); Laboratory of Physics of Materials and Nanomaterials Applied at Environment (LaPhyMNE), Faculty of Sciences in Gabes, Gabes (Tunisia); Bouzid, Houcine [Promising Centre for Sensors and Electronic Devices (PCSED), Najran University, P.O. Box 1988, Najran 11001 (Saudi Arabia); Laboratoire des Matériaux Ferroélectriques, Faculté des Sciences de Sfax, Route Soukra Km 3 5, B.P. 802, F-3018 Sfax (Tunisia); Yousif, A. [Department of Physics, College of Science, Sultan Qaboos University, P.O. Box 36, Code 123, Al Khoud (Oman); Al-Hajry, Ali [Promising Centre for Sensors and Electronic Devices (PCSED), Najran University, P.O. Box 1988, Najran 11001 (Saudi Arabia)

    2014-09-01

    Highlights: • Iron oxides nanoparticles with different sizes are successfully synthesized using sol–gel method. • The obtained nanoparticles are mainly composed of maghemite phase (γ-Fe{sub 2}O{sub 3}). • A non-negligible coercive field suggests that the particles are ferromagnetic. • A mean heating efficiency of 30 W/g is obtained for the smallest particles at 110 kHz and 190 Oe. - Abstract: Iron oxides nanoparticles with different sizes are successfully synthesized using sol–gel method. X-ray diffraction (XRD) and Mössbauer spectroscopy show that the obtained nanoparticles are mainly composed of maghemite phase (γ-Fe{sub 2}O{sub 3}). XRD and transmission electron microscopy (TEM) results suggest that the nanoparticles have sizes ranging from 14 to 30 nm, which are indeed confirmed by large magnetic saturation and high blocking temperature. At room temperature, the observation of a non-negligible coercive field suggests that the particles are ferro/ferrimagnetic. The specific absorption rate (SAR) under an alternating magnetic field is investigated as a function of size, frequency and amplitude of the applied magnetic field. A mean heating efficiency of 30 W/g is obtained for the smallest particles at 110 kHz and 190 Oe, whereas further increase of particle size does not improve significantly the heating efficiency.

  13. Target size analysis by radiation inactivation: a large capacity tube rack for irradiation in a Gammacell 220.

    Science.gov (United States)

    Beauregard, G; Giroux, S; Potier, M

    1983-07-15

    Target size analysis by radiation inactivation is now a well-established method to study structure-function relationships in biologically active macromolecules without prior purification or even solubilization. Recently, it was reported that a relatively low-dose-rate but commonly available gamma source such as the Gammacell 220 (Atomic Energy of Canada, Ltd.) can be used to carry out radiation inactivation experiments providing it is appropriately calibrated with enzymes of known radiation sensitivities (G. Beauregard and M. Potier (1982) Anal. Biochem. 122, 379-384). In this report, a tube rack designed to fit into the irradiation chamber of the Gammacell 220 which allows five experiments (at 30 tubes per experiment) to be carried out simultaneously with both standard and unknown samples is described. The dose rates delivered at different positions in the rack were determined by irradiating rat liver cytosolic neuraminidase, an enzyme of known radiation sensitivity. A better than 2.7% agreement was obtained between experimental dose rate and computed values from isodose curves previously published by other authors (O. A. Curzio and H. O. Quaranta (1982) Int. J. Appl. Radiat. Isot. 33, 1-3).

  14. Distribution analysis of ultra-high molecular mass poly(ethylene oxide) containing silica particles by size-exclusion chromatography with dual light-scattering and refractometric detection.

    Science.gov (United States)

    Porsch, Bedrich; Welinder, Anette; Körner, Anna; Wittgren, Bengt

    2005-03-18

    Two different size-exclusion chromatography (SEC) systems, connected in-line either to a low-angle light scattering (LALS) or to a multiangle light scattering (MALS) detector, are employed for determination of molecular mass distributions (MMD) of poly(ethylene oxide) (PEO) samples having a weight average molecular mass up to eight millions. The detrimental effect of the presence of strongly scattering silica particles in the samples on the light scattering signal can be eliminated using a suitable sample dissolution procedure utilizing silica solubility in aqueous mobile phase. The selection of flow-rate and sample concentration have a large impact on the obtained results. Hydrodynamic retardation phenomena and nonlinearity effects are shown to introduce severe errors in the molecular mass distributions unless flow-rate and sample concentration are kept at sufficiently low levels. Self-compensating ability of the dual detection in flow-rate effects is shown to be the main advantage here. A good agreement between the results obtained using LALS and MALS detection is found provided that a carefully selected angular extrapolation procedure is used in the case of MALS data. Thus, using carefully selected experimental conditions, SEC with light-scattering (LS) and refractometric detection proved to be an efficient technique for MMD characterisation also of ultra-high molecular mass (UHM) PEO polymers.

  15. Signal Formation Processes in Micromegas Detectors and Quality Control for large size Detector Construction for the ATLAS New Small Wheel

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00387450; Rembser, Christoph

    2017-08-04

    The Micromegas technology is one of the most successful modern gaseous detector concepts and widely utilized in nuclear and particle physics experiments. Twenty years of R & D rendered the technology sufficiently mature to be selected as precision tracking detector for the New Small Wheel (NSW) upgrade of the ATLAS Muon spectrometer. This will be the first large scale application of Micromegas in one of the major LHC experiments. However, many of the fundamental microscopic processes in these gaseous detectors are still not fully understood and studies on several detector aspects, like the micromesh geometry, have never been addressed systematically. The studies on signal formation in Micromegas, presented in the first part of this thesis, focuses on the microscopic signal electron loss mechanisms and the amplification processes in electron gas interaction. Based on a detailed model of detector parameter dependencies, these processes are scrutinized in an iterating comparison between exper- imental result...

  16. Effect of high-pressure homogenization preparation on mean globule size and large-diameter tail of oil-in-water injectable emulsions

    Directory of Open Access Journals (Sweden)

    Jie Peng

    2015-12-01

    Full Text Available The effect of different high pressure homogenization energy input parameters on mean diameter droplet size (MDS and droplets with > 5 μm of lipid injectable emulsions were evaluated. All emulsions were prepared at different water bath temperatures or at different rotation speeds and rotor-stator system times, and using different homogenization pressures and numbers of high-pressure system recirculations. The MDS and polydispersity index (PI value of the emulsions were determined using the dynamic light scattering (DLS method, and large-diameter tail assessments were performed using the light-obscuration/single particle optical sensing (LO/SPOS method. Using 1000 bar homogenization pressure and seven recirculations, the energy input parameters related to the rotor-stator system will not have an effect on the final particle size results. When rotor-stator system energy input parameters are fixed, homogenization pressure and recirculation will affect mean particle size and large diameter droplet. Particle size will decrease with increasing homogenization pressure from 400 bar to 1300 bar when homogenization recirculation is fixed; when the homogenization pressure is fixed at 1000 bar, the particle size of both MDS and percent of fat droplets exceeding 5 μm (PFAT5 will decrease with increasing homogenization recirculations, MDS dropped to 173 nm after five cycles and maintained this level, volume-weighted PFAT5 will drop to 0.038% after three cycles, so the “plateau” of MDS will come up later than that of PFAT5, and the optimal particle size is produced when both of them remained at plateau. Excess homogenization recirculation such as nine times under the 1000 bar may lead to PFAT5 increase to 0.060% rather than a decrease; therefore, the high-pressure homogenization procedure is the key factor affecting the particle size distribution of emulsions. Varying storage conditions (4–25°C also influenced particle size, especially the PFAT

  17. Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes.

    Directory of Open Access Journals (Sweden)

    Elijah R Behr

    Full Text Available Marked prolongation of the QT interval on the electrocardiogram associated with the polymorphic ventricular tachycardia Torsades de Pointes is a serious adverse event during treatment with antiarrhythmic drugs and other culprit medications, and is a common cause for drug relabeling and withdrawal. Although clinical risk factors have been identified, the syndrome remains unpredictable in an individual patient. Here we used genome-wide association analysis to search for common predisposing genetic variants. Cases of drug-induced Torsades de Pointes (diTdP, treatment tolerant controls, and general population controls were ascertained across multiple sites using common definitions, and genotyped on the Illumina 610k or 1M-Duo BeadChips. Principal Components Analysis was used to select 216 Northwestern European diTdP cases and 771 ancestry-matched controls, including treatment-tolerant and general population subjects. With these sample sizes, there is 80% power to detect a variant at genome-wide significance with minor allele frequency of 10% and conferring an odds ratio of ≥2.7. Tests of association were carried out for each single nucleotide polymorphism (SNP by logistic regression adjusting for gender and population structure. No SNP reached genome wide-significance; the variant with the lowest P value was rs2276314, a non-synonymous coding variant in C18orf21 (p  =  3×10(-7, odds ratio = 2, 95% confidence intervals: 1.5-2.6. The haplotype formed by rs2276314 and a second SNP, rs767531, was significantly more frequent in controls than cases (p  =  3×10(-9. Expanding the number of controls and a gene-based analysis did not yield significant associations. This study argues that common genomic variants do not contribute importantly to risk for drug-induced Torsades de Pointes across multiple drugs.

  18. Genome Wide Analysis of Drug-Induced Torsades de Pointes: Lack of Common Variants with Large Effect Sizes

    Science.gov (United States)

    Behr, Elijah R.; Ritchie, Marylyn D.; Tanaka, Toshihiro; Kääb, Stefan; Crawford, Dana C.; Nicoletti, Paola; Floratos, Aris; Sinner, Moritz F.; Kannankeril, Prince J.; Wilde, Arthur A. M.; Bezzina, Connie R.; Schulze-Bahr, Eric; Zumhagen, Sven; Guicheney, Pascale; Bishopric, Nanette H.; Marshall, Vanessa; Shakir, Saad; Dalageorgou, Chrysoula; Bevan, Steve; Jamshidi, Yalda; Bastiaenen, Rachel; Myerburg, Robert J.; Schott, Jean-Jacques; Camm, A. John; Steinbeck, Gerhard; Norris, Kris; Altman, Russ B.; Tatonetti, Nicholas P.; Jeffery, Steve; Kubo, Michiaki; Nakamura, Yusuke; Shen, Yufeng; George, Alfred L.; Roden, Dan M.

    2013-01-01

    Marked prolongation of the QT interval on the electrocardiogram associated with the polymorphic ventricular tachycardia Torsades de Pointes is a serious adverse event during treatment with antiarrhythmic drugs and other culprit medications, and is a common cause for drug relabeling and withdrawal. Although clinical risk factors have been identified, the syndrome remains unpredictable in an individual patient. Here we used genome-wide association analysis to search for common predisposing genetic variants. Cases of drug-induced Torsades de Pointes (diTdP), treatment tolerant controls, and general population controls were ascertained across multiple sites using common definitions, and genotyped on the Illumina 610k or 1M-Duo BeadChips. Principal Components Analysis was used to select 216 Northwestern European diTdP cases and 771 ancestry-matched controls, including treatment-tolerant and general population subjects. With these sample sizes, there is 80% power to detect a variant at genome-wide significance with minor allele frequency of 10% and conferring an odds ratio of ≥2.7. Tests of association were carried out for each single nucleotide polymorphism (SNP) by logistic regression adjusting for gender and population structure. No SNP reached genome wide-significance; the variant with the lowest P value was rs2276314, a non-synonymous coding variant in C18orf21 (p  =  3×10−7, odds ratio = 2, 95% confidence intervals: 1.5–2.6). The haplotype formed by rs2276314 and a second SNP, rs767531, was significantly more frequent in controls than cases (p  =  3×10−9). Expanding the number of controls and a gene-based analysis did not yield significant associations. This study argues that common genomic variants do not contribute importantly to risk for drug-induced Torsades de Pointes across multiple drugs. PMID:24223155

  19. Ultrasensitive nonlinear absorption response of large-size topological insulator and application in low-threshold bulk pulsed lasers.

    Science.gov (United States)

    Xu, Jin-Long; Sun, Yi-Jian; He, Jing-Liang; Wang, Yan; Zhu, Zhao-Jie; You, Zhen-Yu; Li, Jian-Fu; Chou, Mitch M C; Lee, Chao-Kuei; Tu, Chao-Yang

    2015-10-07

    Dirac-like topological insulators have attracted strong interest in optoelectronic application because of their unusual and startling properties. Here we report for the first time that the pure topological insulator Bi2Te3 exhibited a naturally ultrasensitive nonlinear absorption response to photoexcitation. The Bi2Te3 sheets with lateral size up to a few micrometers showed extremely low saturation absorption intensities of only 1.1 W/cm(2) at 1.0 and 1.3 μm, respectively. Benefiting from this sensitive response, a Q-switching pulsed laser was achieved in a 1.0 μm Nd:YVO4 laser where the threshold absorbed pump power was only 31 mW. This is the lowest threshold in Q-switched solid-state bulk lasers to the best of our knowledge. A pulse duration of 97 ns was observed with an average power of 26.1 mW. A Q-switched laser at 1.3 μm was also realized with a pulse duration as short as 93 ns. Moreover, the mode locking operation was demonstrated. These results strongly exhibit that Bi2Te3 is a promising optical device for constructing broadband, miniature and integrated high-energy pulsed laser systems with low power consumption. Our work clearly points out a significantly potential avenue for the development of two-dimensional-material-based broadband ultrasensitive photodetector and other optoelectronic devices.

  20. Synthesis of Highly ordered Large Size Mesoporous Silica and Effect of Stabilization as Enzyme Supports in Organic Solvent

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    FSM-16, MCM-41 and SBA-15 types of hexagonal mesoporous silica with a highly ordered 2-dimensional structure were synthesized by using different silicon sources and surfactants. In the 2-dimensional silicate framework, pore size can be uniformly controlled by the combined use of the surfactants having different alkyl chain lengths and the swelling agents(triisopropyl benzene). The pore-diameter of FSM-16 and MCM-41 can be expanded to be 10 nm, SBA-15 to be 15 nm. The crystal regularity was decreased with the increase of the porediameter. In FSM-16 derived from kanemite (silicon source) and MCM-41 from water glass, their anionic characteristics on the pore-wall may be stronger than those of SBA-15 derived from oligomeric tetramethoxysilane(TMOS). We have successfully used FSM-16 and MCM-41 to immobilize the enzyme having cationic residues below isoelectric point. The level of adsorption of enzymes in FSM-16 and MCM-41 was relatively high, but was low in SBA-15 support. The mechanism of enzyme to be adsorbed in mesoporous silica was suggested to be the ionic interactions. In aqueous solutions, horseradish peroxidase(HTP) was immobilized in FSM-16 with 8. 9 nm mesopores and the highest loading amount (183 mg/mg FSM) was obtained, but for the FSM-16 of pore diameter 30 nm only an amount of 28 mg/mg FSM was obtained. The catalytic activity in the organic solvent was high when HRP was immobilized in FSM-16 and MCM-41, but it was low in case of SBA-15.

  1. Simultaneous Cu-, Fe-, and Zn-specific detection of metalloproteins contained in rabbit plasma by size-exclusion chromatography-inductively coupled plasma atomic emission spectroscopy.

    Science.gov (United States)

    Manley, Shawn A; Byrns, Simon; Lyon, Andrew W; Brown, Peter; Gailer, Jürgen

    2009-01-01

    Analytical methods which are capable of determining the plasma or serum metalloproteome have inherent diagnostic value for human diseases associated with increased or decreased concentrations of specific plasma metalloproteins. We have therefore systematically developed a method to rapidly determine the major Cu-, Fe-, and Zn-containing metalloproteins in rabbit plasma (0.5 mL) based on size-exclusion chromatography (SEC; stationary phase Superdex 200, mobile phase phosphate-buffered saline pH 7.4) and the simultaneous online detection of Cu, Fe, and Zn in the column effluent by an inductively coupled plasma atomic emission spectrometer (ICP-AES). Whereas most previous studies reported on the analysis of serum, our investigations clearly demonstrated that the analysis of plasma within 30 min of collection results in the detection of one more Cu peak (blood coagulation factor V) than has been previously reported (transcuprein, ceruloplasmin, albumin-bound Cu, and small molecular weight Cu). The average amount of Cu associated with these five proteins corresponded to 21, 18, 21, 30 and 10% of total plasma Cu, respectively. In contrast, only two Fe metalloproteins (ferritin and transferrin, corresponding to an average of 9 and 91% of total plasma Fe) and approximately five Zn metalloproteins (alpha(2)-macroglobulin and albumin-bound Zn, which corresponded to an average of 10 and 57% of total [corrected] plasma Zn) were detected. Metalloproteins were assigned on the basis of the coelution of the corresponding metal and protein identified by immunoassays or activity-based enzyme assays. The SEC-ICP-AES approach developed allowed the determination of approximately 12 Cu, Fe, and Zn metalloproteins in rabbit plasma within approximately 24 min and can be applied to analyze human plasma, which is potentially useful for diagnosing Cu-, Fe-, and Zn-related diseases.

  2. Effect of particle size on the flux pinning properties of YBa2Cu3O7-δ thin films containing fine Y2O3 nanoprecipitates

    Science.gov (United States)

    Yamasaki, H.

    2016-06-01

    The magnetic-field angle dependence of the critical current density, J c(H, θ), was measured at various temperatures in co-evaporated YBa2Cu3O7-δ (YBCO) thin films. The YBCO films showed volcano-shaped J c(θ) peaks around H//ab, and J c(θ) peaks around H//c were not observed. Film A, deposited at a lower temperature than the commercial standard film B, showed lower J c values at high temperatures (T ≥ 60 K) compared with film B, although film A showed higher J c at T = 20 K. Plan-view transmission electron microscope observations revealed that films A and B contained a high density of fine Y2O3 nanoprecipitates. The modes in the distribution of their cross-sectional areas are 10-20 nm2 in film A and 20-30 nm2 in film B. Because of the smaller particle size, film A showed lower J c at high temperatures owing to the smaller elementary pinning force, f p, but showed higher J c at 20 K where the temperature-dependent coherence length ξ ab (T) was short (˜2 nm) and comparable with the radius of Y2O3 nanoparticles. Film A showed anisotropic scaling behavior at T = 70-80 K, and the T dependence of J c followed ˜(1 - T/T c) m (1 + T/T c)2 (m ≈ 2.5), which was expected from a simple flux-pinning model.

  3. Challenging developments in three decades of accelerator mass spectrometry at ETH: from large particle accelerators to table size instruments.

    Science.gov (United States)

    Suter, Martin

    2010-01-01

    Accelerator mass spectrometry (AMS) was invented for the detection of radiocarbon at natural isotopic concentrations (10(-12) to 10(-15)) more than 30 years ago. Meanwhile this method has also been applied for the analysis of many other long-lived radioisotopes, which are found at very low concentrations. The first investigations were made at large tandem accelerators originally built for nuclear physics research and operating at voltages of 6-12 MV. Today dedicated instruments are mostly used for AMS, which are optimized for associated applications. In the past 15 years, a new generation of much smaller instruments has been developed. For many years it was believed that accelerators with voltages of 2 MV or higher are needed to eliminate the molecular interferences. At these energies the ions are predominantly stripped to charge state 3+, thereby removing the binding electrons of the molecules. In contrast, the new compact facilities use 1+ or 2+ ions. In this case the molecular destruction process is based on molecule-atom collisions in the gas cell. The cross sections for this destruction are sufficiently large that the intensity of molecular components such as (12)CH(2) and (13)CH can be reduced by 10 orders of magnitude. These new facilities can be built much smaller due to the lower energies. Universal instruments providing analysis for many isotopes over the whole range of periodic table have a space requirement of about 4 x 6 m(2); dedicated radiocarbon facilities based on a 200 kV accelerator have a footprint of about 2.5 x 3 m(2). This smallest category of instruments use special technologies: The high voltage terminal with the gas stripper canal is vacuum insulated and the gas is pumped to ground potential through a ceramic pipe. A conventional 200 kV power supply provides the terminal voltage from outside. A review of this new generation of compact AMS facilities is given. Design considerations and performance of these new instruments will be presented

  4. THE STUDY OF HRM SYSTEMS: MARKET ANALYSIS, SELECTION AND IMPLEMENTATION FOR MEDIUM-SIZED AND LARGE BUSINESSES

    Directory of Open Access Journals (Sweden)

    Baranovskaya T. P.

    2016-01-01

    Full Text Available The article reveals the basic concepts, purpose and classification of HRM systems used to manage the organization's staff. The analysis of the international and Russian market of HRM-systems and selected alternatives (seven information systems of this class focused on the Russian practice of large and mediumsized businesses has been performed. The process of implementing an information system involves selecting the system that best suited to the needs of the business. For this purpose, there were developed evaluation criteria of information systems and their importance for the company. This stage of research was conducted through a survey of experts from among the University staff and practitioners. As a result, we have obtained the matrix of evaluations of alternative information systems of HRM and selected class "1C: Salary and personnel management 8". Research demos of the selected HRM system allowed developing a functional model, presented in the form of complex diagrams of cases of modeling language UML 2.0. The developed diagrams clearly reflect the allocated subsystems and their functions, as well as the relationship between the actors of the process and system functions. Summarizing the experience of implementing similar systems, we composed a smartchart showing the main stages of its implementation. The results have practical value and can be used by companies of the considered business segment as specific recommendations

  5. Large size biogas-fed Solid Oxide Fuel Cell power plants with carbon dioxide management: Technical and economic optimization

    Science.gov (United States)

    Curletti, F.; Gandiglio, M.; Lanzini, A.; Santarelli, M.; Maréchal, F.

    2015-10-01

    This article investigates the techno-economic performance of large integrated biogas Solid Oxide Fuel Cell (SOFC) power plants. Both atmospheric and pressurized operation is analysed with CO2 vented or captured. The SOFC module produces a constant electrical power of 1 MWe. Sensitivity analysis and multi-objective optimization are the mathematical tools used to investigate the effects of Fuel Utilization (FU), SOFC operating temperature and pressure on the plant energy and economic performances. FU is the design variable that most affects the plant performance. Pressurized SOFC with hybridization with a gas turbine provides a notable boost in electrical efficiency. For most of the proposed plant configurations, the electrical efficiency ranges in the interval 50-62% (LHV biogas) when a trade-off of between energy and economic performances is applied based on Pareto charts obtained from multi-objective plant optimization. The hybrid SOFC is potentially able to reach an efficiency above 70% when FU is 90%. Carbon capture entails a penalty of more 10 percentage points in pressurized configurations mainly due to the extra energy burdens of captured CO2 pressurization and oxygen production and for the separate and different handling of the anode and cathode exhausts and power recovery from them.

  6. Large population sizes mitigate negative effects of variable weather conditions on fruit set in two spring woodland orchids.

    Science.gov (United States)

    Jacquemyn, Hans; Brys, Rein; Honnay, Olivier

    2009-08-23

    Global circulation models predict increased climatic variability, which could increase variability in demographic rates and affect long-term population viability. In animal-pollinated species, pollination services, and thus fruit and seed set, may be highly variable among years and sites, and depend on both local environmental conditions and climatic variables. Orchid species may be particularly vulnerable to disruption of their pollination services, as most species depend on pollinators for successful fruit set and because seed germination and seedling recruitment are to some extent dependent on the amount of fruits and seeds produced. Better insights into the factors determining fruit and seed set are therefore indispensable for a better understanding of population dynamics and viability of orchid populations under changing climatic conditions. However, very few studies have investigated spatio-temporal variation in fruit set in orchids. Here, we quantified fruit production in eight populations of the orchid Orchis purpurea that does not reward pollinators and 13 populations of the rewarding Neottia (Listera) ovata during five consecutive years (2002-2006). Fruit production in large populations showed much higher stability than that in small populations and was less affected by extreme weather conditions. Our results highlight the potential vulnerability of small orchid populations to an increasingly variable climate through highly unpredictable fruit-set patterns.

  7. Study on thermal decomposition kinetics of limestone with large particle size%大粒径石灰石热分解动力学研究

    Institute of Scientific and Technical Information of China (English)

    陈海; 张世红; 杨海平; 李攀; 陈汉平; 曾军

    2013-01-01

    主要研究大粒径石灰石的煅烧特性,采用热重分析仪研究了5种不同粒径石灰石的煅烧过程.石灰石粒径分布在0.5~10 mm,煅烧温度在900~1 050℃.研究结果表明,粒径越小温度越高石灰石分解速率越快,而且粒径和煅烧温度对石灰石热分解机理也有明显的影响.粒径小温度高时反应符合随机成核和随后生长机理模型,粒径大温度低时反应符合相界面反应机理.当粒径为0.5~1 mm时反应活化能很小,随着粒径的增大反应活化能有所增加,粒径在1~5 mm时活化能变化不大,粒径继续增大(5~10 mm)活化能增大了1倍.%Thermal decomposition experiments of limestone with five different particle sizes were conducted through thermo gravimetric analyzer to study its calcined characteristics with large particle size.The limestone particle sizes were distributed in the range of 0.5~10 mm,and the temperature was controlled at 900~1 050 ℃ during the experiments.Rresults revealed that the smaller the particle size,the higher the temperature and the faster the decomposition.And the particle size and calcining temperature made an obvious influence on the thermal decomposition mechanism.When the particle size was small and the temperature was high,the reaction was in accordance with the randomly nucleating and nucleus growth model,but in contrast,reaction was in accordance with the phase interface mechanism.When the particle size was at 0.5~ 1 mm,reaction activation energy was very small,and with the increase of particle size,reaction activation energy increased,while in the range of 1~5 mm,activation energy fluctuated,with the continuous increase of particle size to 5~10 mm,the activation energy doubled.

  8. Small lesion size measured by colposcopy may predict absence of cervical intraepithelial neoplasia in a large loop excision of the transformation zone specimen.

    Science.gov (United States)

    Munmany, M; Marimon, L; Cardona, M; Nonell, R; Juiz, M; Astudillo, R; Ordi, J; Torné, A; Del Pino, M

    2017-02-01

    To evaluate whether colposcopic measurement of the lesion size at diagnosis and/or human papillomavirus (HPV) genotyping can predict the absence of dysplasia in a large loop excision of the transformation zone (LLETZ) specimen in women treated for squamous intraepithelial lesions/cervical intraepithelial neoplasia (SIL/CIN). Prospective observational study. Tertiary university hospital. A cohort of 116 women who underwent LLETZ because of biopsy-proven low-grade SIL/CIN that had persisted for 2 years, or because of a high-grade SIL/CIN diagnosed in the referral visit and squamocolumnar junction completely visible (types 1 or 2, according to the International Federation of Cervical Pathology and Colposcopy, IFCPC). After LLETZ the women were classified by histology into the study group (absence of SIL/CIN in the surgical specimen, 28/116, 24.1%) and the control group (SIL/CIN in the LLETZ specimen, 88/116, 75.9%). The size of the lesion determined in the diagnostic colposcopy and the HPV genotype were evaluated in all women. The lesion size was significantly smaller in the study group (25.7 ± 37.8 versus 84.5 ± 81.7 mm(2) ; P size of ≤12 mm(2) and HPV types other than 16 or 18 were associated with an absence of SIL/CIN in the LLETZ specimen (P size of ≤12 mm(2) predicted the absence of SIL/CIN (odds ratio, OR 10.6; 95% confidence interval, 95% CI 3.6-30.6; P size of ≤12 mm(2) had a specificity of 90.9% (95% CI 83.0-95.3%) and a negative predictive value of 86.0% (95% CI 77.5-91.6%) to predict the absence of SIL/CIN in the surgical specimen. Small lesion size in diagnostic colposcopy could predict the absence of SIL/CIN in the LLETZ specimen. Colposcopy measurement of lesion size prior to LLETZ may avoid unnecessary treatment. Small lesion size in colposcopic evaluation might predict the absence of SIL/CIN in an LLETZ specimen. © 2016 Royal College of Obstetricians and Gynaecologists.

  9. Non-linear scaling of oxygen consumption and heart rate in a very large cockroach species (Gromphadorhina portentosa): correlated changes with body size and temperature.

    Science.gov (United States)

    Streicher, Jeffrey W; Cox, Christian L; Birchard, Geoffrey F

    2012-04-01

    Although well documented in vertebrates, correlated changes between metabolic rate and cardiovascular function of insects have rarely been described. Using the very large cockroach species Gromphadorhina portentosa, we examined oxygen consumption and heart rate across a range of body sizes and temperatures. Metabolic rate scaled positively and heart rate negatively with body size, but neither scaled linearly. The response of these two variables to temperature was similar. This correlated response to endogenous (body mass) and exogenous (temperature) variables is likely explained by a mutual dependence on similar metabolic substrate use and/or coupled regulatory pathways. The intraspecific scaling for oxygen consumption rate showed an apparent plateauing at body masses greater than about 3 g. An examination of cuticle mass across all instars revealed isometric scaling with no evidence of an ontogenetic shift towards proportionally larger cuticles. Published oxygen consumption rates of other Blattodea species were also examined and, as in our intraspecific examination of G. portentosa, the scaling relationship was found to be non-linear with a decreasing slope at larger body masses. The decreasing slope at very large body masses in both intraspecific and interspecific comparisons may have important implications for future investigations of the relationship between oxygen transport and maximum body size in insects.

  10. Growth of Large-Size SnS Thin Crystals Driven by Oriented Attachment and Applications to Gas Sensors and Photodetectors.

    Science.gov (United States)

    Wang, Jun; Lian, Gang; Xu, Zhenghao; Fu, Chen; Lin, Zhaojun; Li, Liyi; Wang, Qilong; Cui, Deliang; Wong, Ching-Ping

    2016-04-20

    Freestanding large-size SnS thin crystals are synthesized via two-dimensional oriented attachment (OA) growth of colloidal quantum dots (CQDs) in a novel high-pressure solvothermal reaction. The SnS thin crystals present a uniform rectangular shape with a lateral size of 20-30 um and thickness of time and organic ligands results in polycrystal-to-monocrystal formation and defect annihilation. Furthermore, gas sensor and photodetector devices, based on SnS thin single crystals, are also prepared. The sensing devices present high sensitivity, superior selectivity, low detection limit (≪100 ppb) and reversibility to NO2 at room temperature. The fabricated photodetector devices exhibit a high responsivity of 2.04 × 10(3) A W(1-) and high external quantum efficiency of ∼4.75 × 10(5) % at 532 nm, which are much higher than most of the photodetector devices.

  11. The potential distributions, and estimated spatial requirements and population sizes, of the medium to large-sized mammals in the planning domain of the Greater Addo Elephant National Park project

    Directory of Open Access Journals (Sweden)

    A.F. Boshoff

    2002-12-01

    Full Text Available The Greater Addo Elephant National Park project (GAENP involves the establishment of a mega biodiversity reserve in the Eastern Cape, South Africa. Conservation planning in the GAENP planning domain requires systematic information on the potential distributions and estimated spatial requirements, and population sizes of the medium to largesized mammals. The potential distribution of each species is based on a combination of literature survey, a review of their ecological requirements, and consultation with conservation scientists and managers. Spatial requirements were estimated within 21 Mammal Habitat Classes derived from 43 Land Classes delineated by expert-based vegetation and river mapping procedures. These estimates were derived from spreadsheet models based on forage availability estimates and the metabolic requirements of the respective mammal species, and that incorporate modifications of the agriculture-based Large Stock Unit approach. The potential population size of each species was calculated by multiplying its density estimate with the area of suitable habitat. Population sizes were calculated for pristine, or near pristine, habitats alone, and then for these habitats together with potentially restorable habitats for two park planning domain scenarios. These data will enable (a the measurement of the effectiveness of the GAENP in achieving predetermined demographic, genetic and evolutionary targets for mammals that can potentially occur in selected park sizes and configurations, (b decisions regarding acquisition of additional land to achieve these targets to be informed, (c the identification of species for which targets can only be met through metapopulation management,(d park managers to be guided regarding the re-introduction of appropriate species, and (e the application of realistic stocking rates. Where possible, the model predictions were tested by comparison with empirical data, which in general corroborated the

  12. Erosion and break-up of light-gas layers by a horizontal jet in a multi-vessel, large-scale containment test system

    Energy Technology Data Exchange (ETDEWEB)

    Zboray, Robert, E-mail: robert.zboray@psi.ch; Mignot, Guillaume; Kapulla, Ralf; Paladino, Domenico

    2015-09-15

    The distribution and eventual stratification of hydrogen released during a hypothetical severe accident and the stability of the stratification formed in the early phase of the transient is of particular safety concern in Light Water Reactors (LWRs). The large-scale containment test facility PANDA (PSI, Switzerland) has been used to perform a series of four tests examining the erosion and break-up of stratified light-gas layers in the frame of the OECD SETH-2 project. The ultimate goal of the test program is to set-up an experimental data base of high-quality and high-density data that can challenge and validate 3D containment codes like e.g. GOTHIC, GASFLOW or MARS and validate the applicability of CFD codes like FLUENT or CFX for LWR containment problems. The test series discussed here focuses on the erosion of a stratified, helium-rich layer by horizontal steam injection at different locations below the layer. An approach with step-wise increasing complexity has been chosen to examine this problem allowing control over the rate of pressure increase and the occurrence of condensation. The step-wise approach enables a thorough understanding of the influence of different phenomena like position of steam injection, diffusion, pressurization and condensation on the behavior and erosion of the stratified layer.

  13. Effects of pore sizes and oxygen-containing functional groups on desulfurization activity of Fe/NAC prepared by ultrasonic-assisted impregnation

    Science.gov (United States)

    Shu, Song; Guo, Jia-Xiu; Liu, Xiao-Li; Wang, Xue-Jiao; Yin, Hua-Qiang; Luo, De-Ming

    2016-01-01

    A series of Fe-loaded activated carbons treated by HNO3 (Fe/NAC) were prepared by incipient impregnation method with or without ultrasonic assistance and characterized using X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy with energy disperse spectroscope (SEM-EDS), transmission electron microscopy (TEM) and N2 adsorption/desorption. The desulfurization activities were evaluated at a fixed bed reactor under a mixed gas simulated from flue gas. The results showed that desulfurization activity from excellent to poor is as follows: Fe/NAC-60 > Fe/NAC-80 > Fe/NAC-30 > Fe/NAC-15 > Fe/NAC-0 > Fe/NAC-100 > NAC. Fe/NAC-60 exhibits the best desulfurization activity and has breakthrough sulfur capacity of 319 mg/g and breakthrough time of 540 min. The introduction of ultrasonic oscillation does not change the form of Fe oxides on activated carbon but can change the dispersion and relative contents of Fe3O4. The types of oxygen-containing functional groups have no obvious change for all samples but the texture properties show some differences when they are oscillated for different times. The fresh Fe/NAC-60 has a surface area of 1045 m2/g and total pore volume of 0.961 cm3/g with micropore volume of 0.437 cm3/g and is larger than Fe/NAC-0 (823 m2/g, 0.733 and 0.342 cm3/g). After desulfurization, surface area and pore volume of all samples decrease significantly, and those of the exhausted Fe/NAC-60 decrease to 233 m2/g and 0.481 cm3/g, indicating that some byproducts deposit on surface to cover pores. Pore size distribution influences SO2 adsorption, and fresh Fe/NAC-60 has more pore widths centralized at about 0.7 nm and 1.0-2.0 nm and corresponds to an excellent desulfurization activity, showing that micropore is conducive to the removal of SO2.

  14. Design and performance of large-pixel-size high-fill-fraction TES arrays for future X-ray astrophysics missions

    Energy Technology Data Exchange (ETDEWEB)

    Figueroa-Feliciano, E. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States)]. E-mail: enectali@mit.edu; Bandler, S.R. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Chervenak, J. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Finkbeiner, F. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Iyomoto, N. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Kelley, R.L. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Kilbourne, C.A. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Porter, F.S. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Saab, T. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Sadleir, J. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); White, J. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States)

    2006-04-15

    We have designed, modeled, fabricated and tested a 600{mu}m high-fill-fraction microcalorimeter array that will be a good match to the requirements of future X-ray missions. Our devices use transition-edge sensors coupled to overhanging bismuth/copper absorbers to produce arrays with 97% or higher fill fraction. An extensive modeling effort was undertaken in order to accommodate large pixel sizes (500-1000{mu}m) and maintain the best energy resolution possible. The finite thermalization time of the large absorber and the associated position dependence of the pulse shape on absorption position constrain the time constants of the system given a desired energy-resolution performance. We show the results of our analysis and our new pixel design, consisting of a novel TES-on-the-side architecture which creates a controllable TES-absorber conductance.

  15. A probable vacuum state containing a large number of hydrogen atom of excited state or ground state K, Rb or Cs atom

    CERN Document Server

    You, Pei-Lin

    2008-01-01

    The linear Stark effect shows that the first excited state of hydrogen atom has large permanent electric dipole moment (EDM), d(H)=3eao (ao is Bohr radius). Using special capacitors our experiments discovered that the ground state K, Rb or Cs atom is polar atom with a large EDM of the order of eao as hydrogen atom of excited state. Their capacitance(C) at different voltage (V) was measured. The C-V curve shows that the saturation polarization of K, Rb or Cs vapor has be observed when the field E more than ten to the fifth power V/m. When the saturation polarization appeared, nearly all K, Rb or Cs atoms(more than 98 percent) turned toward the direction of the field, and C is approximately equal to Co (Co is vacuum capacitance) or their dielectric constant is nearly the same as vacuum! K, Rb or Cs vapor just exist in the lowest energy state, so we see the vacuum state containing a large number of atoms! Due to the saturation polarization of hydrogen vapor of excited state is easily appears, we conjecture that ...

  16. Structural and optical characteristics of graphene quantum dots size-controlled and well-aligned on a large scale by polystyrene-nanosphere lithography

    Science.gov (United States)

    Duck Oh, Si; Kim, Jungkil; Lee, Dae Hun; Kim, Ju Hwan; Jang, Chan Wook; Kim, Sung; Choi, Suk-Ho

    2016-01-01

    Graphene quantum dots (GQDs) are one of the most attractive graphene nanostructures due to their potential optoelectronic device applications, but it is a challenge to accurately control the size and arrangement of GQDs. In this report, we fabricate well-aligned GQDs on a large area by polystyrene (PS)-nanosphere (NS) lithography and study their structural and optical properties. Single-layer graphene grown on a Cu foil by chemical vapour deposition is patterned by reactive ion etching employing aligned PS-NS arrays as an etching mask. The size (d) of the GQDs is controlled from 75 to 23 nm by varying the etching time, as proved by scanning electron microscopy and atomic force microscopy. This method is well valid for both rigid/flexible target substrates and even for multilayer graphene formed by piling up single layers. The absorption peak of the GQDs is blue-shifted with respect to that of a graphene sheet, and is sequentially shifted to higher energies by reducing d, consistent with the quantum confinement effect (QCE). The Raman D-to-G band intensity ratio shows an almost monotonic increase with decreasing d, resulting from the dominant contribution of the edge states at the periphery of smaller GQDs. The G-band frequency shows a three-step size-dependence: initial increase, interim saturation, and final decrease with decreasing d, thought to be caused by the competition between the QCE and edge-induced strain effect.

  17. The episode of genetic drift defining the migration of humans out of Africa is derived from a large east African population size.

    Directory of Open Access Journals (Sweden)

    Nuha Elhassan

    Full Text Available Human genetic variation particularly in Africa is still poorly understood. This is despite a consensus on the large African effective population size compared to populations from other continents. Based on sequencing of the mitochondrial Cytochrome C Oxidase subunit II (MT-CO2, and genome wide microsatellite data we observe evidence suggesting the effective size (Ne of humans to be larger than the current estimates, with a foci of increased genetic diversity in east Africa, and a population size of east Africans being at least 2-6 fold larger than other populations. Both phylogenetic and network analysis indicate that east Africans possess more ancestral lineages in comparison to various continental populations placing them at the root of the human evolutionary tree. Our results also affirm east Africa as the likely spot from which migration towards Asia has taken place. The study reflects the spectacular level of sequence variation within east Africans in comparison to the global sample, and appeals for further studies that may contribute towards filling the existing gaps in the database. The implication of these data to current genomic research, as well as the need to carry out defined studies of human genetic variation that includes more African populations; particularly east Africans is paramount.

  18. Selection of Main Motor Speed Control Method in Large-Sized Pumping Station%大型泵站主电机调速方式的选择

    Institute of Scientific and Technical Information of China (English)

    龚维明; 陆一忠; 赵培江; 莫岳平; 陆臻辉

    2014-01-01

    Analysis was made to the application and its advantages and disadvantages of stator variable frequency speed control method in pumping station. Introduction was made to the feasibility of application for AC excitation motors with a large amount of application in wind power generation in pumping station. This paper studied the application prospect of inner feed-back speed control method which has been successfully applied in tap water supply plants in pumping station. During the building and rebuilding of large-size and medium-size pumping stations, new type of speed control method was actively popularized, so as to reach investment saving, energy saving and lifting pumping station technology goals.%分析了定子变频调速方式在泵站的应用情况及其优缺点;介绍了在风力发电中获得大量应用的交流励磁电机在泵站中应用的可行性;研究了已在自来水厂等获得成功应用的内反馈调速方式在泵站中的应用前景。提出应在大中型泵站建设与改造中积极推广应用新型调速方式,以达到节约投资、节约能源和提高泵站技术的目的。

  19. Large-sized SmBCO single crystals with T sub c over 93 K grown in atmospheric ambient by crystal pulling

    CERN Document Server

    Yao Xin; Shiohara, Y

    2003-01-01

    Sm sub 1 sub + sub x Ba sub 2 sub - sub x Cu sub 3 O sub z (SmBCO) single crystals were grown under atmospheric ambient by the top-seeded solution growth method. Inductively coupled plasma results indicate that there is negligible Sm substitution for Ba sites in the grown SmBCO crystals, although they crystallized from different Ba-Cu-O solvents with a wide composition range (Ba/Cu ratio of 0.5-0.6). As a result, these crystals show high superconducting critical transition temperature values (T sub c) of over 93 K with a sharp transition width after oxygenation. A large-sized crystal with an a-b plane of 23 x 22 mm sup 2 and a c-axis of 19 mm was obtained at a high growth rate of nearly 0.13 mm h sup - sup 1. In short, with more controllable thermodynamic parameters, SmBCO single crystals can readily achieve both large size and high superconducting properties. (rapid communication)

  20. Composition and relative abundance of terrestrial medium- and large-sized mammals of Parque Estadual da Serra do Brigadeiro, Minas Gerais, Brazil

    Directory of Open Access Journals (Sweden)

    André Valle Nunes

    2012-09-01

    Full Text Available Three northern areas of Parque Estadual da Serra do Brigadeiro (PESB were sampled for terrestrial medium- and large-sized mammals, using camera traps, for twelve months. Nine wild species and one domestic species were registered, through 49 records. The community’s composition was based on an exponential series with dominance of few species. In contrast, there was a relatively high proportion of species that might be “rare” in the community observed, with dominance of puma (Puma concolor over the other ones. The results show that the area named Vale Perdido is the most important one for the conservation of mammals, because the estimated species richness is higher there (13.99 ± 2.23 when compared to that of the other two areas, which had a richness of 6.00 ± 1.41 and 6.00 ± 1.00, respectively. It’s possible that the structural and spatial characteristics of Vale Perdido favored the use of this area by the species. The structure of the community of medium-and large-sized terrestrial mammals of PESB is unstructured or in a structuring phase. Possibly, this model was caused by negative historical effects of the occupation and extraction that the region underwent in the 1960s.