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Sample records for large part determined

  1. Uncertainty for Part Density Determination: An Update

    Energy Technology Data Exchange (ETDEWEB)

    Valdez, Mario Orlando [Los Alamos National Laboratory

    2016-12-14

    Accurate and precise density measurements by hydrostatic weighing requires the use of an analytical balance, configured with a suspension system, to both measure the weight of a part in water and in air. Additionally, the densities of these liquid media (water and air) must be precisely known for the part density determination. To validate the accuracy and precision of these measurements, uncertainty statements are required. The work in this report is a revision of an original report written more than a decade ago, specifically applying principles and guidelines suggested by the Guide to the Expression of Uncertainty in Measurement (GUM) for determining the part density uncertainty through sensitivity analysis. In this work, updated derivations are provided; an original example is revised with the updated derivations and appendix, provided solely to uncertainty evaluations using Monte Carlo techniques, specifically using the NIST Uncertainty Machine, as a viable alternative method.

  2. Magnitude determination for large underground nuclear explosions

    Energy Technology Data Exchange (ETDEWEB)

    Porter, Lawrence D [Lawrence Radiation Laboratory, University of California, Livermore, CA (United States)

    1970-05-15

    A method is presented for determining the local magnitudes for large underground nuclear explosions. The Gutenberg-Richter nomograph is applied to the peak amplitudes for 24 large underground nuclear explosions that took place in Nevada. The amplitudes were measured at 18 California Wood-Anderson stations located 150-810 km from the explosion epicenter. The variation of the individual station magnitudes and magnitude corrections and the variation of the average and rms error estimates in the magnitude determinations are examined with respect to distance, azimuth, and event location. The magnitude prediction capability of the Gutenberg-Richter nomograph is examined on the basis of these two criteria, and certain corrections are suggested. The azimuthal dependence of the individual station magnitudes is investigated, and corrections for the California stations are calculated. Statistical weighting schemes for two-component data are employed, and the assumptions and limitations in the use of peak amplitudes are discussed. (author)

  3. Methods of humidity determination Part II: Determination of material humidity

    OpenAIRE

    Rübner, Katrin; Balköse, Devrim; Robens, E.

    2008-01-01

    Part II covers the most common methods of measuring the humidity of solid material. State of water near solid surfaces, gravimetric measurement of material humidity, measurement of water sorption isotherms, chemical methods for determination of water content, measurement of material humidity via the gas phase, standardisation, cosmonautical observations are reviewed.

  4. Use of citric acid for large parts decontamination

    International Nuclear Information System (INIS)

    Holland, M.E.

    1979-01-01

    Laboratory and field studies have been performed to identify and evaluate chemical decontamination agents to replace ammonium carbonate, an environmentally unacceptable compound, in the decontamination facility for large process equipment at the Portsmouth Gaseous Diffusion Plant. Preliminary screening of over 40 possible decontamination agents on the basis of efficiency, availability, toxicity, cost, corrosiveness, and practicality indicated sodium carbonate and citric acid to be the most promising. Extensive laboratory studies were performed with these two reagents. Corrosion rates, decontamination factors, uranium recovery efficiencies, technetium ( 99 Tc)/ion exchange removal effects, and possible environmental impacts were determined or investigated. Favorable results were found in all areas. Detailed monitoring and analysis during two-week trial periods in which sodium carbonate and citric acid were used in the large parts decontamination facility resulted in similar evaluation and conclusions. Because it has cleaning properties not possessed by sodium carbonate, and because it eliminated several operational problems by incorporating two acidic decontamination reagents (citric and nitric acids) instead of one basic reagent (sodium or ammonium carbonate) and one acidic reagent (nitric acid), citric acid was selected for one-year field testing. On the basis of its excellent performance in the field tests, citric acid is recommended as a permanent replacement for ammonium carbonate in the decontamination facility for large process equipment

  5. Explosive force of primacord grid forms large sheet metal parts

    Science.gov (United States)

    1966-01-01

    Primacord which is woven through fish netting in a grid pattern is used for explosive forming of large sheet metal parts. The explosive force generated by the primacord detonation is uniformly distributed over the entire surface of the sheet metal workpiece.

  6. Determining large deflections in rectangular combined loaded ...

    Indian Academy of Sciences (India)

    (Bisshopp & Drucker 1945; Scott et al 1955; Lau 1982; Rao & Rao 1986; Baker 1993; Lee et al 1993; Frisch-Fay 1962; Fertis 1999). Prathap and Varadan (1976) had calculated large deflections in cantilever beams made of non-linear Ramberg–Osgood type material on which concentrated load effected on the free end.

  7. Determination of Selected Properties of Teletype Parts.

    Science.gov (United States)

    1985-10-01

    THtS REPORT IS NOT TO BC USED IN WHOLE OR IN PART rOR ADVERTISING OR SALES PROMOTION PURPOSES ASD $1 64 PNCVIOus COTION OF THIS FORM MAY at useo...REPoRT 1s NOT TO BE USED IN WHOLE of IN PART FOa AOvCRTsINO oR SALES PROMoTIoN PuRPW-- PR S* P0gwSOUS -oD ION Of .. . , FOM MAY O uSTm. AI-W---,AT AS ?M 57

  8. Determining minimum lubrication film for machine parts

    Science.gov (United States)

    Hamrock, B. J.; Dowson, D.

    1978-01-01

    Formula predicts minimum film thickness required for fully-flooded ball bearings, gears, and cams. Formula is result of study to determine complete theoretical solution of isothermal elasto-hydrodynamic lubrication of fully-flooded elliptical contacts.

  9. Radiochemical determination of methylmercury chloride Part 1

    International Nuclear Information System (INIS)

    Stary, J.; Prasilova, J.

    1976-01-01

    The isotope exchange between methylmercury species and an excess of inorganic radiomercury in sulphuric acid medium has been used for the simple determination of methylmercury chloride down to 0.01 ppm. The determination is not influenced by the presence of a great excess of other metals, however, chlorides, bromides and iodides interfere in higher concentrations. It has been found that the isotope exchange between CH 3 HgCl and 203 HgCl 4 2- (or 203 HgCl 2 ) in 0.01-3M hydrochloric acid is extremely slow, for the bimolecular reaction the rate constant is lower than 10 -3 mol -1 s -1 at 25 deg C. The isotope exchange rate between methylmercury chloride and mercuric-nitrate 0n on 0.5M sulphuric acid is higher. The isotope exchange is a bimolecular reaction with a rate constant k=0.050+-0.004 mol -1 s -1 at 25 deg C. (T.I.)

  10. Complexometric determination, Part II: Complexometric determination of Cu2+-ions

    Directory of Open Access Journals (Sweden)

    Rajković Miloš B.

    2002-01-01

    Full Text Available A copper-selective electrode of the coated wire type based on sulphidized copper wire was applied successfully for determining Cu(II ions by complexometric titration with the disodium salt of EDTA (complexon III. By the formation of internal complex compounds with the Cu(II ion, the copper concentration in the solution decreases, and all this is followed by a change of potential of the indicator system Cu-DWISE (or Cu-EDWISE/SCE. At the terminal point of titration, when all the Cu(II ions are already utilized for the formation of the complex with EDTA, there occurs a steep rise of potential, thus enabling us, through the first or second derivative to note the quantity of copper that is present in the solution. Copper-selective electrode showed a responsivity towards titration with EDTA as a complexing agent, with the absence of "fatigue" due to a great number of repeated measurings. Errors occurring during quantitative measurements were more a characteristic of the overall procedure which involve, because of the impossibility of the complete absence of subjectivity, a constant error, and the reproducibility of the results confirmed this fact. The disodium salt of EDTA appeared as a very efficient titrant in all titrations and with various concentrations ot Cu(II ions in the solution, with somewhat weaker response at lower concentrations in the solution.

  11. The determinants of part-time work in Metropolitan Lima

    OpenAIRE

    Manuel Enrique Saavedra Martinez

    2011-01-01

    The following paper examines the part-time work in Metropolitan Lima in 2008. The overall objective is to identify the determinants of the incidence of part-time work in Lima. We worked with one Probit econometric model, measured by the National Survey of Households (NSH), which explores the job characteristics of people. This will determine the presence of part-time workers in the areas of trade, health, education and communication; also realized that this group has completed university stud...

  12. The determinants of part-time work in Metropolitan Lima

    OpenAIRE

    Saavedra Martinez, Manuel Enrique

    2012-01-01

    The following paper examines the part-time work in Metropolitan Lima in 2008. The overall objective is to identify the determinants of the incidence of part-time work in Lima. We worked with one Probit econometric model, measured by the National Survey of Households (NSH), which explores the job characteristics of people. This will determine the presence of part-time workers in the areas of trade, health, education and communication; also realized that this group has completed university stud...

  13. The determinants of part-time work in Metropolitan Lima

    Directory of Open Access Journals (Sweden)

    Manuel Enrique Saavedra Martinez

    2011-12-01

    Full Text Available The following paper examines the part-time work in Metropolitan Lima in 2008. The overall objective is to identify the determinants of the incidence of part-time work in Lima. We worked with one Probit econometric model, measured by the National Survey of Households (NSH, which explores the job characteristics of people. This will determine the presence of part-time workers in the areas of trade, health, education and communication; also realized that this group has completed university studies and incomplete, and the woman has a probability of 83,11397% more than men of working part time.

  14. Forging technology for large nuclear pressure vessel parts

    International Nuclear Information System (INIS)

    Kakimoto, Hideki; Ikegami, Tomonori

    2014-01-01

    The increasing output of nuclear power generation calls for larger vessels for next-generation nuclear power plants. A vessel with an increased diameter requires increased load for its forging, which can make it difficult to use a conventional solid die. In order to reduce the forging load, a rotary incremental forging method has been applied to hot forging. This method includes pressing and rotating a material in an incremental manner such that a target shape is obtained. This study aimed at improving the accuracy of numerical simulation for the rotary incremental forging to reduce the load when forging large vessels. This has enabled the temperature of the material and flow stress to be precisely predicted; an example of this is reported in the paper. Specifically, the heat transfer coefficient to be used for the numerical simulation had been determined experimentally from a small-scale hot-forging. The reduction of the flow stress associated with incremental forging, had been deduced from a compression test, and the value was applied to the numerical simulation. A preform was designed on the basis of the above simulation to perform a 1/1 size scale experiment. A precision of better than 5% has been confirmed for the shape prediction. (author)

  15. Characterization of large volume HPGe detectors. Part II: Experimental results

    International Nuclear Information System (INIS)

    Bruyneel, Bart; Reiter, Peter; Pascovici, Gheorghe

    2006-01-01

    Measurements on a 12-fold segmented, n-type, large volume, irregular shaped HPGe detector were performed in order to determine the parameters of anisotropic mobility for electrons and holes as charge carriers created by γ-ray interactions. To characterize the electron mobility the complete outer detector surface was scanned in small steps employing photopeak interactions at 60keV. A precise measurement of the hole drift anisotropy was performed with 356keV γ-rays. The drift velocity anisotropy and crystal geometry cause considerable rise time differences in pulse shapes depending on the position of the spatial charge carrier creation. Pulse shapes of direct and transient signals are reproduced by weighting potential calculations with high precision. The measured angular dependence of rise times is caused by the anisotropic mobility, crystal geometry, changing field strength and space charge effects. Preamplified signals were processed employing digital spectroscopy electronics. Response functions, crosstalk contributions and averaging procedures were taken into account implying novel methods due to the segmentation of the Ge-crystal and digital signal processing electronics

  16. Does internationalisation of technology determine technological diversification in large firms?

    OpenAIRE

    Christian Le Bas; Pari Patel

    2005-01-01

    The purpose of the paper is to examine the relationship between technological diversification and internationalisation of technology for large multinational firms, operating at the world technological frontier. More precisely we address the question as to whether internationalisation determines diversification. The analysis is based on a rich database of the European patenting activity of 345 large multinational firms with the highest levels of patenting over two periods of time (1988-1990 an...

  17. Large scale sodium interactions. Part 1. Test facility design

    International Nuclear Information System (INIS)

    King, D.L.; Smaardyk, J.E.; Sallach, R.A.

    1977-01-01

    During the design of the test facility for large scale sodium interaction testing, an attempt was made to keep the system as simple and yet versatile as possible; therefore, a once through design was employed as opposed to any type of conventional sodium ''loop.'' The initial series of tests conducted at the facility call for rapidly dropping from 20 kg to 225 kg of sodium at temperatures from 825 0 K to 1125 0 K into concrete crucibles. The basic system layout is described. A commercial drum heater is used to melt the sodium which is in 55 gallon drums and then a slight argon pressurization is used to force the liquid sodium through a metallic filter and into a dump tank. Then the sodium dump tank is heated to the desired temperature. A diaphragm is mechanically ruptured and the sodium is dumped into a crucible that is housed inside a large steel test chamber

  18. Model Experiments for the Determination of Airflow in Large Spaces

    DEFF Research Database (Denmark)

    Nielsen, Peter V.

    Model experiments are one of the methods used for the determination of airflow in large spaces. This paper will discuss the formation of the governing dimensionless numbers. It is shown that experiments with a reduced scale often will necessitate a fully developed turbulence level of the flow....... Details of the flow from supply openings are very important for the determination of room air distribution. It is in some cases possible to make a simplified supply opening for the model experiment....

  19. Phased array inspection of large size forged steel parts

    Science.gov (United States)

    Dupont-Marillia, Frederic; Jahazi, Mohammad; Belanger, Pierre

    2018-04-01

    High strength forged steel requires uncompromising quality to warrant advance performance for numerous critical applications. Ultrasonic inspection is commonly used in nondestructive testing to detect cracks and other defects. In steel blocks of relatively small dimensions (at least two directions not exceeding a few centimetres), phased array inspection is a trusted method to generate images of the inside of the blocks and therefore identify and size defects. However, casting of large size forged ingots introduces changes of mechanical parameters such as grain size, the Young's modulus, the Poisson's ratio, and the chemical composition. These heterogeneities affect the wave propagation, and consequently, the reliability of ultrasonic inspection and the imaging capabilities for these blocks. In this context, a custom phased array transducer designed for a 40-ton bainitic forged ingot was investigated. Following a previous study that provided local mechanical parameters for a similar block, two-dimensional simulations were made to compute the optimal transducer parameters including the pitch, width and number of elements. It appeared that depending on the number of elements, backwall reconstruction can generate high amplitude artefacts. Indeed, the large dimensions of the simulated block introduce numerous constructive interferences from backwall reflections which may lead to important artefacts. To increase image quality, the reconstruction algorithm was adapted and promising results were observed and compared with the scattering cone filter method available in the CIVA software.

  20. Towards automated diffraction tomography. Part II-Cell parameter determination

    International Nuclear Information System (INIS)

    Kolb, U.; Gorelik, T.; Otten, M.T.

    2008-01-01

    Automated diffraction tomography (ADT) allows the collection of three-dimensional (3d) diffraction data sets from crystals down to a size of only few nanometres. Imaging is done in STEM mode, and diffraction data are collected with quasi-parallel beam nanoelectron diffraction (NED). Here, we present a set of developed processing steps necessary for automatic unit-cell parameter determination from the collected 3d diffraction data. Cell parameter determination is done via extraction of peak positions from a recorded data set (called the data reduction path) followed by subsequent cluster analysis of difference vectors. The procedure of lattice parameter determination is presented in detail for a beam-sensitive organic material. Independently, we demonstrate a potential (called the full integration path) based on 3d reconstruction of the reciprocal space visualising special structural features of materials such as partial disorder. Furthermore, we describe new features implemented into the acquisition part

  1. Two Proposals for determination of large reactivity of reactor

    International Nuclear Information System (INIS)

    Kaneko, Yoshihiko; Nagao, Yoshiharu; Yamane, Tsuyoshi; Takeuchi, Mituo

    1999-01-01

    Two Proposals for determination of large reactivity of reactors are presented. One is for large positive reactivity. The other is for large negative reactivity. Existing experimental methods for determination of large positive reactivity, the fuel addition method and the neutron adsorption substitution method were analyzed. It is found that both the experimental methods are possibly affected to the substantially large systematic error up to ∼ 20%, when the value of the excess multiplication factor comes into the range close to ∼20%Δk. To cope with this difficulty, a revised method is validly proposed. The revised method evaluates the value of the potential excess multiplication factor as the consecutive increments of the effective multiplication factor in a virtual core, which are converted from those in an actual core by multiplying a conversion factor f to it. The conversion factor f is to be obtained in principle by calculation. Numerical experiments were done on a slab reactor using one group diffusion model. The rod drop experimental method is widely used for determination of large negative negative reactivity values. The decay of the neutron density followed by initiating the insertion of the rod is obliged to be slowed down according to its speed. It is proved by analysis based on the one point reactor kinetics that in such a case the integral counting method hitherto used tend to significantly underestimate the absolute values of negative reactivity, even if the insertion time is in the range of 1-2 s. As for the High Temperature Engineering Test Reactor (HTTR), the insertion time will be lengthened up to 4-6 s. In order to overcome the difficulty , the delayed integral counting method is proposed, in which the integration of neutron counting starts after the rod drop has been completed and the counts before is evaluated by calculation using one point reactor kinetics. This is because the influence of the insertion time on the decay of the neutron

  2. Automated Determination of Magnitude and Source Length of Large Earthquakes

    Science.gov (United States)

    Wang, D.; Kawakatsu, H.; Zhuang, J.; Mori, J. J.; Maeda, T.; Tsuruoka, H.; Zhao, X.

    2017-12-01

    Rapid determination of earthquake magnitude is of importance for estimating shaking damages, and tsunami hazards. However, due to the complexity of source process, accurately estimating magnitude for great earthquakes in minutes after origin time is still a challenge. Mw is an accurate estimate for large earthquakes. However, calculating Mw requires the whole wave trains including P, S, and surface phases, which takes tens of minutes to reach stations at tele-seismic distances. To speed up the calculation, methods using W phase and body wave are developed for fast estimating earthquake sizes. Besides these methods that involve Green's Functions and inversions, there are other approaches that use empirically simulated relations to estimate earthquake magnitudes, usually for large earthquakes. The nature of simple implementation and straightforward calculation made these approaches widely applied at many institutions such as the Pacific Tsunami Warning Center, the Japan Meteorological Agency, and the USGS. Here we developed an approach that was originated from Hara [2007], estimating magnitude by considering P-wave displacement and source duration. We introduced a back-projection technique [Wang et al., 2016] instead to estimate source duration using array data from a high-sensitive seismograph network (Hi-net). The introduction of back-projection improves the method in two ways. Firstly, the source duration could be accurately determined by seismic array. Secondly, the results can be more rapidly calculated, and data derived from farther stations are not required. We purpose to develop an automated system for determining fast and reliable source information of large shallow seismic events based on real time data of a dense regional array and global data, for earthquakes that occur at distance of roughly 30°- 85° from the array center. This system can offer fast and robust estimates of magnitudes and rupture extensions of large earthquakes in 6 to 13 min (plus

  3. Glass: a small part of the Climate Change problem, a large part of the solution

    Directory of Open Access Journals (Sweden)

    Stockdale, J.

    2009-04-01

    Full Text Available The challenging EU targets for reducing greenhouse gas emissions and generating electricity from renewable sources were established as – 20% and 20% by 2020. As part of the strategy, EU confirmed in 2007 the need to save around 300 million tonnes of CO2 per year from EU buildings by 2020. Housing itself accounts for some 40% of emissions, mostly associated with heating. Industry will be expected to source and use appropriate materials and process technologies to improve their own energy consumption and at the same time deliver products that permit to reach those targets. This article examines the relationship between the emissions from relevant sectors of the glass industry and compares them with the carbon savings that can be achieved with the products the industry makes. Four main areas are discussed: glass fibre insulation, advanced glazing (low emissivity glass and advanced solar glass, continuous filament glass fibre and special glass applications. It is suggested that as well as considering the use of free allowances or border carbon adjustment, member states need to take account of the benefit of these products when formulating emission constraint policies; a carbon credit feedback loop should be also explored to encourage cheaper production and installation and avoid carbon leakage.

    La UE ha establecido los objetivos de reducción de emisiones de CO2 en -20% y de generación de electricidad a partir de energías renovables en el 20% para el año 2020. Como parte de esta estrategia la UE confirmó en 2007 la necesidad de reducir en 300 millones de toneladas por año las emisiones provenientes de los edificios en el mismo año 2020. El parque de viviendas aporta alrededor del 40% de las emisiones, básicamente relacionadas con sistemas de calefacción. Se espera de la industria que utilice procesos apropiados para mejorar su propio consumo energético y al mismo tiempo desarrolle y produzca materiales que

  4. Determination of Absorbed Dose in Large 60-Co Fields Radiotherapy

    International Nuclear Information System (INIS)

    Hrsak, H.

    2003-01-01

    Radiation in radiotherapy has selective impact on ill and healthy tissue. During the therapy the healthy tissue receives certain amount of dose. Therefore dose calculations in outer radiotherapy must be accurate because too high doses produce damage in healthy tissue and too low doses cannot ensure efficient treatment of cancer cells. A requirement on accuracy in the dose calculations has lead to improvement of detectors, and development of absolute and relative dosimetry. Determination of the dose distribution with use of computer is based on data provided by the relative dosimetry. This paper compares the percentage depth doses in cubic water phantoms of various dimensions with percentage depth doses calculated with use of Mayneord factor from the experimental depth doses measured in water phantom of large dimension. Depth doses in water phantoms were calculated by the model of empirical dosimetrical functions. The calculations were based on the assumption that large 6 0C o photon field exceeds the phantom's limits. The experimental basis for dose calculations by the model of empirical dosimetrical functions were exposure doses measured in air and dose reduction factors because of finite phantom dimensions. Calculations were performed by fortran 90 software. It was found that the deviation of dosimetric model was small in comparison to the experimental data. (author)

  5. Scramjet test flow reconstruction for a large-scale expansion tube, Part 2: axisymmetric CFD analysis

    Science.gov (United States)

    Gildfind, D. E.; Jacobs, P. A.; Morgan, R. G.; Chan, W. Y. K.; Gollan, R. J.

    2017-11-01

    This paper presents the second part of a study aiming to accurately characterise a Mach 10 scramjet test flow generated using a large free-piston-driven expansion tube. Part 1 described the experimental set-up, the quasi-one-dimensional simulation of the full facility, and the hybrid analysis technique used to compute the nozzle exit test flow properties. The second stage of the hybrid analysis applies the computed 1-D shock tube flow history as an inflow to a high-fidelity two-dimensional-axisymmetric analysis of the acceleration tube. The acceleration tube exit flow history is then applied as an inflow to a further refined axisymmetric nozzle model, providing the final nozzle exit test flow properties and thereby completing the analysis. This paper presents the results of the axisymmetric analyses. These simulations are shown to closely reproduce experimentally measured shock speeds and acceleration tube static pressure histories, as well as nozzle centreline static and impact pressure histories. The hybrid scheme less successfully predicts the diameter of the core test flow; however, this property is readily measured through experimental pitot surveys. In combination, the full test flow history can be accurately determined.

  6. Corrosion and deposit determination in large diameter pipes by radiography

    International Nuclear Information System (INIS)

    Harara, W.

    2006-08-01

    Two steel reference pipes with outer diameters of 8 and 12 inches were machined to make artificial defects on each of them, such as inside and outside steps of different wall thicknesses, inside and outside flat bottomed holes (FBH) of different diameters and depths on steps, flat area (FA), and ground patch (GP). The artificial defect were made to simulate natural corrosion attack as regular corrosion and pitting. The two reference pipes were tested according to tangential radiography technique and double wall single image technique. Tangential radiography technique had been applied using Co-60 radio-isotope to determine the steps thicknesses, the FBH, the remaining wall thickness under the FA, the remaining wall thickness above the GP, and the minimum detectable thickness of the artificial cement deposit on the two reference pipes, with and without insulation. Double wall single image technique had also been applied on the two reference pipes with and without insulation using Ir-192 radio-isotope to measure the flat bottomed holes depths, GP depth, and FA depth by density measurement. The measurement results obtained from the radiographs confirm that, tangential radiography technique can be applied to detect and evaluate the inside and outside regular corrosion attack in the large diameter pipes. It can also be applied to detect and evaluate the outside FBH with depth equal or greater than 10%. Inside 10% FBH and inside 20% FBH can not be detected if their diameters are not larger than certain value related to diameter and wall thickness of the pipe under test. Increasing the film density up to 5 outside the pipe did not provide any detection improvement of 10% and 20% inside FBH. Tangential radiography technique can also be applied to detect and measure the deposit inside the pipes. Double wall technique can be applied as an alternative method of the tangential radiography technique to detect and to evaluate the shallow and small diameter, 10% and 20% inside FBH

  7. [Determinants of the choice of part time employment and nurses' satisfaction: a multicentre descriptive study].

    Science.gov (United States)

    Ferrazzo, Martino; Filippi, Mauro; Meneghetti, Giulia; Palese, Alvisa

    2012-01-01

    To describe the main determinants for the choice of part time employment in Italian nurses and its' impact on work satisfaction. The main factors were identified with a focus-group. A questionnaire with 26 items for the choice of part time and 24 for work satisfaction was then devised and administered to part time nurses (503) of 5 North Italian hospitals. Two-hundred fifty-five nurses/471 answered the questionnaire. The choice of part time was voluntary for the large majority of nurses (251, 98.4%) except for 4 (1.6%) that asked for it for health problems (personal or of the spouse). Part time nurses are more satisfied for the relationships with colleagues (average 3; SD 0.6), the opportunity to deal with responsibilities (2.9; SD 0.6) and to have free time (2.9; SD 0.6). CONCLUSIONS; Part time is a need for mothers. Part time nurses complain for lack of access to information on patients and lack of involvement in ward projects and planned changes, possibly to be considered signals of isolation.

  8. Determining Baseline Stress-Related Hormone Values in Large Cetaceans

    Science.gov (United States)

    2015-09-30

    levels will be transformative for our understanding of the extent of exposure and the potential effect on the health of these animals and offers...cerumen as well as blubber from the same animal . While blubber cortisol concentrations will be a reflection of an indistinguishable time frame from...of the samples collected thus far from both museum holdings as well as fresh carcass samples. It should be noted that as part of our collection we

  9. 17 CFR Appendix B to Part 420 - Sample Large Position Report

    Science.gov (United States)

    2010-04-01

    ..., and as collateral for financial derivatives and other securities transactions $ Total Memorandum 1... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Sample Large Position Report B Appendix B to Part 420 Commodity and Securities Exchanges DEPARTMENT OF THE TREASURY REGULATIONS UNDER...

  10. Determinants of Part-Time Work of High School Seniors.

    Science.gov (United States)

    Hotchkiss, Lawrence

    1986-01-01

    Assesses effects on student part-time employment outcomes of personal characteristics (i.e., gender, race) and institutional characteristics (i.e., vocational high school, participation in cooperative education). Reports that supply theory explains student employment outcomes better than demand theory. (CH)

  11. Determinants of Part-Time Adult Student Participation in Education.

    Science.gov (United States)

    Hawk, Thomas R.

    A study was conducted to identify the factors that influence adults to continue their education by taking formal course work on a part-time basis. Using May 1981 Current Population Survey data gathered by the Bureau of the Census, the study assessed the importance of price, socioeconomic characteristics, family income, and unemployment rates in…

  12. Determination of the Tapping Part Diameter of the Thread Mill

    Directory of Open Access Journals (Sweden)

    A. E. Dreval'

    2015-01-01

    Full Text Available Currently, there is a tendency to increase the proportion of thread milling operations, among other ways of tapping, which is associated with increasing number of CNC machines, flexibility and versatility of the process.Developments presently existing in the RF and used in the thread mills deal, mainly, with the thread milling cutter designs, to process internal and external thread with straight flutes made from high-speed steel.The paper presents a technique to calculate and select the initial design parameters, i.e. the external diameter of the tapping part of thread milling cutter, which is chosen as a basic computational design. The analysis of directories of tool companies containing foreign de-signs of solid thread end-milling cutters has shown that most of them rep-resent the thread cutter designs made of solid carbide. There are solid and interlocking side milling cutters, which use a tapping part both as a single-disk and as a multi-disk one; chip flutes are made to be both as direct and as screw; solid designs of cutters are made from carbide with a diameter of up to 20 ... 25 mm; thread cutters can be left- and right-hand cutting; Designs of the combined thread mills are proposed; internal channels are used for coolant supply.It is shown that the purpose of the external diameter of the tapping part of the thread mill should take into account the effect of the thread mill diameter on the milling process performance, precision of thread profile received, taper thread, tool strength, and the volume of flutes.The analysis has shown that when choosing the external diameter of the thread mill it worth taking its maximum diameter to improve the char-acteristics of the process under the restrictions imposed on the accuracy of the formed thread.

  13. Language structure is partly determined by social structure.

    Directory of Open Access Journals (Sweden)

    Gary Lupyan

    Full Text Available BACKGROUND: Languages differ greatly both in their syntactic and morphological systems and in the social environments in which they exist. We challenge the view that language grammars are unrelated to social environments in which they are learned and used. METHODOLOGY/PRINCIPAL FINDINGS: We conducted a statistical analysis of >2,000 languages using a combination of demographic sources and the World Atlas of Language Structures--a database of structural language properties. We found strong relationships between linguistic factors related to morphological complexity, and demographic/socio-historical factors such as the number of language users, geographic spread, and degree of language contact. The analyses suggest that languages spoken by large groups have simpler inflectional morphology than languages spoken by smaller groups as measured on a variety of factors such as case systems and complexity of conjugations. Additionally, languages spoken by large groups are much more likely to use lexical strategies in place of inflectional morphology to encode evidentiality, negation, aspect, and possession. Our findings indicate that just as biological organisms are shaped by ecological niches, language structures appear to adapt to the environment (niche in which they are being learned and used. As adults learn a language, features that are difficult for them to acquire, are less likely to be passed on to subsequent learners. Languages used for communication in large groups that include adult learners appear to have been subjected to such selection. Conversely, the morphological complexity common to languages used in small groups increases redundancy which may facilitate language learning by infants. CONCLUSIONS/SIGNIFICANCE: We hypothesize that language structures are subjected to different evolutionary pressures in different social environments. Just as biological organisms are shaped by ecological niches, language structures appear to adapt to the

  14. METHOD FOR DETERMINING THE MAXIMUM ARRANGEMENT FACTOR OF FOOTWEAR PARTS

    Directory of Open Access Journals (Sweden)

    DRIŞCU Mariana

    2014-05-01

    Full Text Available By classic methodology, designing footwear is a very complex and laborious activity. That is because classic methodology requires many graphic executions using manual means, which consume a lot of the producer’s time. Moreover, the results of this classical methodology may contain many inaccuracies with the most unpleasant consequences for the footwear producer. Thus, the costumer that buys a footwear product by taking into consideration the characteristics written on the product (size, width can notice after a period that the product has flaws because of the inadequate design. In order to avoid this kind of situations, the strictest scientific criteria must be followed when one designs a footwear product. The decisive step in this way has been made some time ago, when, as a result of powerful technical development and massive implementation of electronical calculus systems and informatics, This paper presents a product software for determining all possible arrangements of a footwear product’s reference points, in order to automatically acquire the maximum arrangement factor. The user multiplies the pattern in order to find the economic arrangement for the reference points. In this purpose, the user must probe few arrangement variants, in the translation and rotate-translation system. The same process is used in establishing the arrangement factor for the two points of reference of the designed footwear product. After probing several variants of arrangement in the translation and rotation and translation systems, the maximum arrangement factors are chosen. This allows the user to estimate the material wastes.

  15. Steam turbines of large output especially for nuclear power stations. Part 1

    International Nuclear Information System (INIS)

    Drahny, J.; Stasny, M.

    1986-01-01

    At the international conference, 53 papers were presented in 3 sessions dealing with the design of large output steam turbines, with problems of flow in steam turbines, and with the reliability and service life of steam turbines. Part 1 of the conference proceedings contains two introductory papers, one reviewing the 100 years history of steam turbines (not included in INIS), the other giving an overview of the development of steam turbines in the eighties; and the 13 papers heard in the session on steam turbine design, all inputted in INIS. (A.K.)

  16. Unusually large tsunamis frequent a currently creeping part of the Aleutian megathrust

    Science.gov (United States)

    Witter, Robert C.; Carver, G.A.; Briggs, Richard; Gelfenbaum, Guy R.; Koehler, R.D.; La Selle, SeanPaul M.; Bender, Adrian M.; Engelhart, S.E.; Hemphill-Haley, E.; Hill, Troy D.

    2016-01-01

    Current models used to assess earthquake and tsunami hazards are inadequate where creep dominates a subduction megathrust. Here we report geological evidence for large tsunamis, occurring on average every 300–340 years, near the source areas of the 1946 and 1957 Aleutian tsunamis. These areas bookend a postulated seismic gap over 200 km long where modern geodetic measurements indicate that the megathrust is currently creeping. At Sedanka Island, evidence for large tsunamis includes six sand sheets that blanket a lowland facing the Pacific Ocean, rise to 15 m above mean sea level, contain marine diatoms, cap terraces, adjoin evidence for scour, and date from the past 1700 years. The youngest sheet, and modern drift logs found as far as 800 m inland and >18 m elevation, likely record the 1957 tsunami. Modern creep on the megathrust coexists with previously unrecognized tsunami sources along this part of the Aleutian Subduction Zone.

  17. 49 CFR Appendix E to Part 26 - Individual Determinations of Social and Economic Disadvantage

    Science.gov (United States)

    2010-10-01

    ... Disadvantage E Appendix E to Part 26 Transportation Office of the Secretary of Transportation PARTICIPATION BY... Appendix E to Part 26—Individual Determinations of Social and Economic Disadvantage The following guidance... disadvantage determinations (see 13 CFR 124.103(c) and 124.104). Social Disadvantage I. Socially disadvantaged...

  18. Interaction in the large energetics companies in the Republic of Macedonia (Part 3)

    International Nuclear Information System (INIS)

    Janevski, Risto

    2000-01-01

    After the disintegration of former power energetic system of Yugoslavia 1991, the Republic of Macedonia has faced enormous problems in the energetic field. It was necessary to realize all options in order to secure enough electric power for normal economic capacities function. In that course a direct involvement of five large companies, which represent very significant energetic subjects, will largely determine the future energetic conditions and circumstances in our country. These are the following companies: P.E. Electric Power Co. of Macedonia; Heat Power Co.; HEK Jugohrom; Fenimak. In this paper the energetic system of the OKTA Crude Oil Refinery from 1991-1998 is analyzed, as well as its characteristics and plans for the future development

  19. Development of Spray on Bag for manufacturing of large composites parts: Diffusivity analysis

    Science.gov (United States)

    Dempah, Maxime Joseph

    Bagging materials are utilized in many composites manufacturing processes. The selection is mainly driven by cost, temperature requirements, chemical compatibility and tear properties of the bag. The air barrier properties of the bag are assumed to be adequate or in many cases are not considered at all. However, the gas barrier property of a bag is the most critical parameter, as it can negatively affect the quality of the final laminate. The barrier property is a function of the bag material, uniformity, thickness and temperature. Improved barrier properties are needed for large parts, high pressure consolidated components and structures where air stays entrapped on the part surface. The air resistance property of the film is defined as permeability and is investigated in this thesis. A model was developed to evaluate the gas transport through the film and an experimental cell was implemented to characterize various commercial films. Understanding and characterizing the transport phenomena through the film allows optimization of the bagging material for various manufacturing processes. Spray-on-Bag is a scalable alternative bagging method compared to standard films. The approach allows in-situ fabrication of the bag on large and complex geometry structures where optimization of the bag properties can be varied on a local level. An experimental setup was developed and implemented using a six axis robot and an automated spraying system. Experiments were performed on a flat surface and specimens were characterized and compared to conventional films. Air barrier properties were within range of standard film approaches showing the potential to fabricate net shape bagging structures in an automated process.

  20. PART 2: LARGE PARTICLE MODELLING Simulation of particle filtration processes in deformable media

    Directory of Open Access Journals (Sweden)

    Gernot Boiger

    2008-06-01

    Full Text Available In filtration processes it is necessary to consider both, the interaction of thefluid with the solid parts as well as the effect of particles carried in the fluidand accumulated on the solid. While part 1 of this paper deals with themodelling of fluid structure interaction effects, the accumulation of dirtparticles will be addressed in this paper. A closer look is taken on theimplementation of a spherical, LAGRANGIAN particle model suitable forsmall and large particles. As dirt accumulates in the fluid stream, it interactswith the surrounding filter fibre structure and over time causes modificationsof the filter characteristics. The calculation of particle force interactioneffects is necessary for an adequate simulation of this situation. A detailedDiscrete Phase Lagrange Model was developed to take into account thetwo-way coupling of the fluid and accumulated particles. The simulation oflarge particles and the fluid-structure interaction is realised in a single finitevolume flow solver on the basis of the OpenSource software OpenFoam.

  1. Portable neutron moisture gage for the moisture determination of structure parts

    International Nuclear Information System (INIS)

    Harnisch, M.

    1985-01-01

    For determining the moisture of structure parts during building or before repairing a portable neutron moisture gage consisting of a neutron probe and pulse analyzer has been developed. The measuring process, calibration, and prerequisites of application are briefly discussed

  2. 49 CFR Appendix E to Part 512 - Consumer Assistance to Recycle and Save (CARS) Class Determinations

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 6 2010-10-01 2010-10-01 false Consumer Assistance to Recycle and Save (CARS) Class Determinations E Appendix E to Part 512 Transportation Other Regulations Relating to... CONFIDENTIAL BUSINESS INFORMATION Pt. 512, App. E Appendix E to Part 512—Consumer Assistance to Recycle and...

  3. Agri-Environmental Resource Management by Large-Scale Collective Action: Determining KEY Success Factors

    Science.gov (United States)

    Uetake, Tetsuya

    2015-01-01

    Purpose: Large-scale collective action is necessary when managing agricultural natural resources such as biodiversity and water quality. This paper determines the key factors to the success of such action. Design/Methodology/Approach: This paper analyses four large-scale collective actions used to manage agri-environmental resources in Canada and…

  4. Usage of advanced thick airfoils for the outer part of very large offshore turbines

    International Nuclear Information System (INIS)

    Grasso, F; Ceyhan, O

    2014-01-01

    Nowadays one of the big challenges in wind energy is connected to the development of very large wind turbines with 100 m blades and 8-10MW power production. The European project INNWIND.EU plays an important role in this challenge because it is focused on exploring and exploiting technical innovations to make these machines not only feasible but also cost effective. In this context, the present work investigates the benefits of adopting thick airfoils also at the outer part of the blade. In fact, if these airfoils are comparable to the existing thinner ones in terms of aerodynamics, the extra thickness would lead to a save in weight. Lightweight blades would visibly contribute to reduce the cost of energy of the turbines and make them cost effective. The reference turbine defined in INNWIND.EU project has been adjusted to use the new airfoils. The results show that the rotor performance is not sacrificed when the 24% airfoils are replaced by the ECN 30% thick airfoils, while 24% extra thickness can be obtained

  5. Overcurrent protection of transformers. Part 2: Traditional and new fusing philosophies for small and large transformers

    Energy Technology Data Exchange (ETDEWEB)

    Cook, C. J.; Niemira, J. K.

    2003-07-01

    New and traditional fusing philosophies for protecting transformers are discussed. This second in a two-part paper covers selection criteria for a transformer-primary fuse to protect the transformer consistent with industry-accepted through-fault protection curves. Also covered are the principles of coordination as they relate to the proper selection of the primary-side fuse and power fuses and the principles underlying the protection of load-side conductors and cables. The critical nature of secondary fault protection on small three-phase transformers used on industrial, commercial, and institutional power systems, as well as small-to-medium size three-phase power transformers used in utility substations is emphasized, in view of the long lead time and expense involved in replacing these transformers. In contrast, no special protection recommendations are made for small-kVA overhead distribution transformers, since they are not considered likely to experience secondary faults, and the rare faults that do occur will not likely be detected and cleared by the primary fuse. Also of importance is the fact that these transformers are inexpensive and readily available. Overall, large fuse rating, used in combination with a tank-mounted surge arrester is recommended, because it can provide better transformer protection than the smaller fuse ratings traditionally employed. 4 refs., 2 tabs., 4 figs.

  6. 27 CFR 41.39 - Determination of sale price of large cigars.

    Science.gov (United States)

    2010-04-01

    ... addition to money, goods or services exchanged for cigars may be considered as part of the sale price. See... TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY (CONTINUED) TOBACCO IMPORTATION OF TOBACCO PRODUCTS, CIGARETTE PAPERS AND TUBES, AND PROCESSED TOBACCO Taxes Classification of Large Cigars and Cigarettes § 41...

  7. Self-Calibrated In-Process Photogrammetry for Large Raw Part Measurement and Alignment before Machining.

    Science.gov (United States)

    Mendikute, Alberto; Yagüe-Fabra, José A; Zatarain, Mikel; Bertelsen, Álvaro; Leizea, Ibai

    2017-09-09

    Photogrammetry methods are being used more and more as a 3D technique for large scale metrology applications in industry. Optical targets are placed on an object and images are taken around it, where measuring traceability is provided by precise off-process pre-calibrated digital cameras and scale bars. According to the 2D target image coordinates, target 3D coordinates and camera views are jointly computed. One of the applications of photogrammetry is the measurement of raw part surfaces prior to its machining. For this application, post-process bundle adjustment has usually been adopted for computing the 3D scene. With that approach, a high computation time is observed, leading in practice to time consuming and user dependent iterative review and re-processing procedures until an adequate set of images is taken, limiting its potential for fast, easy-to-use, and precise measurements. In this paper, a new efficient procedure is presented for solving the bundle adjustment problem in portable photogrammetry. In-process bundle computing capability is demonstrated on a consumer grade desktop PC, enabling quasi real time 2D image and 3D scene computing. Additionally, a method for the self-calibration of camera and lens distortion has been integrated into the in-process approach due to its potential for highest precision when using low cost non-specialized digital cameras. Measurement traceability is set only by scale bars available in the measuring scene, avoiding the uncertainty contribution of off-process camera calibration procedures or the use of special purpose calibration artifacts. The developed self-calibrated in-process photogrammetry has been evaluated both in a pilot case scenario and in industrial scenarios for raw part measurement, showing a total in-process computing time typically below 1 s per image up to a maximum of 2 s during the last stages of the computed industrial scenes, along with a relative precision of 1/10,000 (e.g. 0.1 mm error in 1 m) with

  8. Determining casting defects in near-net shape casting aluminum parts by computed tomography

    Science.gov (United States)

    Li, Jiehua; Oberdorfer, Bernd; Habe, Daniel; Schumacher, Peter

    2018-03-01

    Three types of near-net shape casting aluminum parts were investigated by computed tomography to determine casting defects and evaluate quality. The first, second, and third parts were produced by low-pressure die casting (Al-12Si-0.8Cu-0.5Fe-0.9Mg-0.7Ni-0.2Zn alloy), die casting (A356, Al-7Si-0.3Mg), and semi-solid casting (A356, Al-7Si-0.3Mg), respectively. Unlike die casting (second part), low-pressure die casting (first part) significantly reduced the formation of casting defects (i.e., porosity) due to its smooth filling and solidification under pressure. No significant casting defect was observed in the third part, and this absence of defects indicates that semi-solid casting could produce high-quality near-net shape casting aluminum parts. Moreover, casting defects were mostly distributed along the eutectic grain boundaries. This finding reveals that refinement of eutectic grains is necessary to optimize the distribution of casting defects and reduce their size. This investigation demonstrated that computed tomography is an efficient method to determine casting defects in near-net shape casting aluminum parts.

  9. Multidetector row computed tomography in bowel obstruction. Part 2. Large bowel obstruction

    Energy Technology Data Exchange (ETDEWEB)

    Sinha, R. [Department of Radiology, Glenfield Hospital, Leicester (United Kingdom)]. E-mail: rakesh.sinha@uhl-tr.nhs.uk; Verma, R. [Department of Radiology, Glenfield Hospital, Leicester (United Kingdom)

    2005-10-01

    Large bowel obstruction may present as an emergency as high-grade colonic obstruction and can result in perforation. Perforated large bowel obstruction causes faecal peritonitis, which can result in high morbidity and mortality. Multidetector row computed tomography (MDCT) has the potential of providing an accurate diagnosis of large bowel obstruction. The rapid acquisition of images within one breath-hold reduces misregistration artefacts than can occur in critically ill or uncooperative patients. The following is a review of the various causes of large bowel obstruction with emphasis on important pathogenic factors, CT appearances and the use of multiplanar reformatted images in the diagnostic workup.

  10. The part-time wage penalty in European countries: how large is it for men?

    OpenAIRE

    O'Dorchai, Sile Padraigin; Plasman, Robert; Rycx, François

    2007-01-01

    Economic theory advances a number of reasons for the existence of a wage gap between part-time and full-time workers. Empirical work has concentrated on the wage effects of part-time work for women. For men, much less empirical evidence exists, mainly because of lacking data. In this paper, we take advantage of access to unique harmonised matched employer-employee data (i.e. the 1995 European Structure of Earnings Survey) to investigate the magnitude and sources of the part-time wage penalty ...

  11. Applying of neural networks in determination of replacement cycle of spare parts

    International Nuclear Information System (INIS)

    Saric, Tomislav; Majdandzic; Niko; Lujic, Roberto

    2003-01-01

    The article shows neural networks applicability to determine expected working time of equipment components before the damage. The results based on measure - simulated values of suggested model have been presented. Advantages of suggested model have been analyzed compared to traditional way of replacement of spare parts and components. Implementation possibility of suggested model in Management Information Maintenance System has been described. (author)

  12. Determination of 129I in large soil samples after alkaline wet disintegration

    International Nuclear Information System (INIS)

    Bunzl, K.; Kracke, W.

    1992-01-01

    Large soil samples (up to 500 g) can conveniently be disintegrated by hydrogen peroxide in an utility tank under alkaline conditions to determine subsequently 129 I by neutron activation analysis. Interfering elements such as Br are removed already before neutron irradiation to reduce the radiation exposure of the personnel. The precision of the method is 129 I also by the combustion method. (orig.)

  13. Differential antibiotic sensitivity determined by the large ribosomal subunit in thermophilic archaea.

    OpenAIRE

    Ruggero, D; Londei, P

    1996-01-01

    Hybrid ribosomes obtained by mixing the ribosomal subunits of the extremely thermophilic archaea Sulfolobus solfataricus and Desulfurococcus mobilis were tested for their sensitivity to selected antibiotics. It is shown that structural differences in the large ribosomal subunits determine qualitatively and quantitatively the patterns of response to alpha-sarcin and paromomycin in these species.

  14. Determinants of salivary evening alpha-amylase in a large sample free of psychopathology

    NARCIS (Netherlands)

    Veen, Gerthe; Giltay, Erik J.; Vreeburg, Sophie A.; Licht, Carmilla M. M.; Cobbaert, Christa M.; Zitman, Frans G.; Penninx, Brenda W. J. H.

    Objective: Recently, salivary alpha-amylase (sAA) has been proposed as a suitable index for sympathetic activity and dysregulation of the autonomic nervous system (ANS). Although determinants of sAA have been described, they have not been studied within the same study with a large sample size

  15. Some new evidence on the determinants of large- and small-firm innovation

    NARCIS (Netherlands)

    B. van Dijk (Bob); R. den Hertog; A.R. Thurik (Roy); A.J. Menkveld (Bert)

    1997-01-01

    textabstractEmpirical analyses presented by Acs and Audretsch suggest differences in the market structure determinants of innovation between large and small firms in U.S. manufacturing. The evidence they offer is ambiguous. By using data for a different country (The Netherlands), a different measure

  16. DETERMINATION OF TRANSMISSION GEAR RATIO IN MECHANICAL PART OF TRACTOR ELECTRO-MECHANICAL TRANSMISSION

    Directory of Open Access Journals (Sweden)

    Ch. I. Zhdanovich

    2016-01-01

    Full Text Available A methodology has been developed for selection of gear number and transmission gear ratios in mechanical part of a wheel-type tractor with electro-mechanical transmission containing a propulsion asynchronous electric motor with variablefrequency control. The paper proposes to determine a transmission gear ratio on the basis of the following: provision of wheel torque dependence on tractor speed which is the best one for a traction process and during transfer from one gear to the other; provision of nominal operational mode of the electric motor for all tractor operations where it is working for a long period of time; provision of minimum possible number of gears; complete realization of internal combustion engine power on the tractor wheels at limit operational mode of the electric motor. As a characteristic of the asynchronous electric motor with variable-frequency control contains various portions which can be used either completely or partially due to operating conditions, the gear number is determined in the process of transmission gear ration finding but not prior to this. A wheel torque of the tractor with electro-mechanical transmission can be limited according to the following factors: grip of wheel with supporting surface; maximum power of an internal combustion engine which can be transferred to the wheels and a torque which is developed by a propulsion electric motor. It is not proposed to exceed nominal operational mode of the propulsion electric motor for all the operations of the tractor if it is working for a long period of time because in the case of significant excess of the nominal operational mode of the asynchronous electric motor its rather long operation leads to low efficiency and high losses in power, large heat liberation and consequently requires to develop more complicated system for electric motor cooling. An excess of nominal electric motor torque can be justified for short-term operational modes because in this case

  17. Non-Destructive Thermography Analysis of Impact Damage on Large-Scale CFRP Automotive Parts

    Science.gov (United States)

    Maier, Alexander; Schmidt, Roland; Oswald-Tranta, Beate; Schledjewski, Ralf

    2014-01-01

    Laminated composites are increasingly used in aeronautics and the wind energy industry, as well as in the automotive industry. In these applications, the construction and processing need to fulfill the highest requirements regarding weight and mechanical properties. Environmental issues, like fuel consumption and CO2-footprint, set new challenges in producing lightweight parts that meet the highly monitored standards for these branches. In the automotive industry, one main aspect of construction is the impact behavior of structural parts. To verify the quality of parts made from composite materials with little effort, cost and time, non-destructive test methods are increasingly used. A highly recommended non-destructive testing method is thermography analysis. In this work, a prototype for a car’s base plate was produced by using vacuum infusion. For research work, testing specimens were produced with the same multi-layer build up as the prototypes. These specimens were charged with defined loads in impact tests to simulate the effect of stone chips. Afterwards, the impacted specimens were investigated with thermography analysis. The research results in that work will help to understand the possible fields of application and the usage of thermography analysis as the first quick and economic failure detection method for automotive parts. PMID:28788464

  18. Non-Destructive Thermography Analysis of Impact Damage on Large-Scale CFRP Automotive Parts

    Directory of Open Access Journals (Sweden)

    Alexander Maier

    2014-01-01

    Full Text Available Laminated composites are increasingly used in aeronautics and the wind energy industry, as well as in the automotive industry. In these applications, the construction and processing need to fulfill the highest requirements regarding weight and mechanical properties. Environmental issues, like fuel consumption and CO2-footprint, set new challenges in producing lightweight parts that meet the highly monitored standards for these branches. In the automotive industry, one main aspect of construction is the impact behavior of structural parts. To verify the quality of parts made from composite materials with little effort, cost and time, non-destructive test methods are increasingly used. A highly recommended non-destructive testing method is thermography analysis. In this work, a prototype for a car’s base plate was produced by using vacuum infusion. For research work, testing specimens were produced with the same multi-layer build up as the prototypes. These specimens were charged with defined loads in impact tests to simulate the effect of stone chips. Afterwards, the impacted specimens were investigated with thermography analysis. The research results in that work will help to understand the possible fields of application and the usage of thermography analysis as the first quick and economic failure detection method for automotive parts.

  19. Non-Destructive Thermography Analysis of Impact Damage on Large-Scale CFRP Automotive Parts.

    Science.gov (United States)

    Maier, Alexander; Schmidt, Roland; Oswald-Tranta, Beate; Schledjewski, Ralf

    2014-01-14

    Laminated composites are increasingly used in aeronautics and the wind energy industry, as well as in the automotive industry. In these applications, the construction and processing need to fulfill the highest requirements regarding weight and mechanical properties. Environmental issues, like fuel consumption and CO₂-footprint, set new challenges in producing lightweight parts that meet the highly monitored standards for these branches. In the automotive industry, one main aspect of construction is the impact behavior of structural parts. To verify the quality of parts made from composite materials with little effort, cost and time, non-destructive test methods are increasingly used. A highly recommended non-destructive testing method is thermography analysis. In this work, a prototype for a car's base plate was produced by using vacuum infusion. For research work, testing specimens were produced with the same multi-layer build up as the prototypes. These specimens were charged with defined loads in impact tests to simulate the effect of stone chips. Afterwards, the impacted specimens were investigated with thermography analysis. The research results in that work will help to understand the possible fields of application and the usage of thermography analysis as the first quick and economic failure detection method for automotive parts.

  20. Very large thermal rectification in bulk composites consisting partly of icosahedral quasicrystals

    International Nuclear Information System (INIS)

    Takeuchi, Tsunehiro

    2014-01-01

    The bulk thermal rectifiers usable at a high temperature above 300 K were developed by making full use of the unusual electron thermal conductivity of icosahedral quasicrystals. The unusual electron thermal conductivity was caused by a synergy effect of quasiperiodicity and by a narrow pseudogap at the Fermi level. The rectification ratio, defined by TRR = |J large |/|J small |, reached vary large values exceeding 2.0. This significant thermal rectification would lead to new practical applications for the heat management. (paper)

  1. Improved Monkey-King Genetic Algorithm for Solving Large Winner Determination in Combinatorial Auction

    Science.gov (United States)

    Li, Yuzhong

    Using GA solve the winner determination problem (WDP) with large bids and items, run under different distribution, because the search space is large, constraint complex and it may easy to produce infeasible solution, would affect the efficiency and quality of algorithm. This paper present improved MKGA, including three operator: preprocessing, insert bid and exchange recombination, and use Monkey-king elite preservation strategy. Experimental results show that improved MKGA is better than SGA in population size and computation. The problem that traditional branch and bound algorithm hard to solve, improved MKGA can solve and achieve better effect.

  2. Large picture archiving and communication systems of the world--Part 2.

    Science.gov (United States)

    Bauman, R A; Gell, G; Dwyer, S J

    1996-11-01

    A survey of 82 institutions worldwide was done in 1995 to identify large picture archiving and communication systems (PACS) in clinical operation. A continuing strong trend toward the creation and operation of large PACS was identified. In the 15 months since the first such survey the number of clinical large PACS went from 13 to 23, almost a doubling in that short interval. New systems were added in Asia, Europe, and North America. A strong move to primary interpretation from soft copy was identified, and filmless radiology has become a reality. Workstations for interpretation reside mainly within radiology, but one-third of reporting PACS have more than 20 workstations outside of radiology. Fiber distributed data interface networks were the most numerous, but a variety of networks was reported to be in use. Replies on various display times showed surprisingly good, albeit diverse, speeds. The planned archive length of many systems was 60 months, with usually more than 1 year of data on-line. The main large archive and off-line storage media for these systems were optical disks and magneto-optical disks. Compression was not used before interpretation in most cases, but many systems used 2.5:1 compression for on-line, interpreted cases and 10:1 compression for longer-term archiving. A move to digital imaging and communication in medicine interface usage was identified.

  3. [Determination of inorganic elements in different parts of Sonchus oleraceus L by flame atomic absorption spectrometry].

    Science.gov (United States)

    Wang, Nai-Xing; Cui, Xue-Gui; Du, Ai-Qin; Mao, Hong-Zhi

    2007-06-01

    Flame atomic absorption spectrometry with air-acetylene flame was used for the determination of inorganic metal elements in different parts ( flower, leaf, stem and root) of Sonchus oleraceus L. The contents of Ca, Mg, K, Na, Fe, Mn, Cu, Zn, Cr, Co, Ni, Pb and Cd in the flower, leaf, stem and root of Sonchus oleraceus L were compared. The order from high to low of the additive weight (microg x g(-1)) for the 13 kinds of metal elements is as follows: leaf (77 213.72) > flower (47 927.15) > stem(42 280.99) > root (28 131.18). From the experimental results it was found that there were considerable differences in the contents of the metal elements in different parts, and there were richer contents of Fe, Zn, Mn and Cu in root and flower, which are necessary to human health, than in other parts.

  4. Method for determining correction factors induced by irradiation of ionization chamber cables in large radiation field

    International Nuclear Information System (INIS)

    Rodrigues, L.L.C.

    1988-01-01

    A simple method was developed to be suggested to hospital physicists in order to be followed during large radiation field dosimetry, to evaluate the effects of cables, connectors and extension cables irradiation and to determine correction factors for each system or geometry. All quality control tests were performed according to the International Electrotechnical Commission for three clinical dosimeters. Photon and electron irradiation effects for cables, connectors and extention cables were investigated under different experimental conditions by means of measurements of chamber sensitivity to a standard radiation source of 90 Sr. The radiation induced leakage current was also measured for cables, connectors and extension cables irradiated by photons and electrons. All measurements were performed at standard dosimetry conditions. Finally, measurements were performed in large fields. Cable factors and leakage factors were determined by the relation between chamber responses for irradiated and unirradiated cables. (author) [pt

  5. Determination of heavy metals in soil and different parts of Diplazium esculentum (medicinal fern)

    Science.gov (United States)

    Jasim, Hind S.; Idris, Mushrifah; Abdullah, Aminah; Kadhum, A. A. H.

    2014-09-01

    Diplazium esculentum is a widely used medicinal fern in Malaysia and other regions worldwide. Heavy metals in plants should be determined because prolonged human intake of toxic trace elements, even at low doses, results in organ malfunction and causes chronic toxicity. Hence, substantial information should be obtained from plants that grow on soils containing high concentrations of heavy metals. This study aimed to determine the physicochemical characteristics of soil and heavy metal concentrations (Pb, Cr, Mn, Cu, and Zn) in different parts of D. esculentum and soil, which were collected from the fern garden of Universiti Kebangsaan Malaysia. Results showed that heavy metals were highly accumulated in D. esculentum roots.

  6. DETERMINATION ОF DRESS ROLL OPTIMAL RADIUS WHILE PRODUCING PARTS WITH TROCHOIDAL PROFILE

    Directory of Open Access Journals (Sweden)

    E. N. Yankevich

    2008-01-01

    Full Text Available The paper considers determination of the dress roll optimal radius while producing parts having trohoidal profile with the help of grinding method that presupposes application of grinding disk. In this case disk profile has been cut-in by diamond dressing. Two methods for determination of calculation of the dress roll optimal radius have been proposed in the paper. On the basis of the satellite gear of the planetary pin reducer whose profile presents a trochoid it has been shown that the obtained results pertaining to two proposed methods conform with each other.

  7. Malaysia: where big is still better. For Malays, large families are part of the plan.

    Science.gov (United States)

    1993-11-03

    The benefits of various-sized families in Malaysia were discussed by several women and supplemented with official statements on family planning (FP). The Director of the National Population and Family Development, Dr. Raj Karim, advised that maternal health is jeopardized when women have more than five children. About 30% of reproductive age women in Malaysia have five or more children. A Federation of FP Associations spokesperson agreed that women should be advised of the dangers of bearing over five children, of the importance of spacing births two to four years apart, and of the ideal age of childbearing (21-39 years). The government lacks an official policy on family size. The government position is, however, compatible with Islamic teachings on spacing in order to protect the health of the mother and child. Islamic law does not permit sterilization or abortion. The "fatwas" of Islamic teaching may have been misconstrued by those not using any form of contraception. Dr. Karim, who has five children, reported that having a large family can be difficult for a woman with a job, a career, and a husband or when both parents work. Most Malays desire large families. The average Malay family size was 4.1 children in 1990; Malaysian Chinese have fertility of 2.3 children and Malaysian Indians have 2.6 children. People say that the benefits outweigh the hardships of a large family.

  8. Application of revised procedure on determining large excess reactivity of operating reactor. Fuel addition method

    International Nuclear Information System (INIS)

    Nagao, Yoshiharu

    2002-01-01

    The fuel addition method or the neutron absorption substitution method have been used for determination of large excess multiplication factor of large sized reactors. It has been pointed out, however, that all the experimental methods are possibly not free from the substantially large systematic error up to 20%, when the value of the excess multiplication factor exceeds about 15%Δk. Then, a basic idea of a revised procedure was proposed to cope with the problem, which converts the increase of multiplication factor in an actual core to that in a virtual core by calculation, because its value is in principle defined not for the former but the latter core. This paper proves that the revised procedure is able to be applicable for large sized research and test reactors through the theoretical analyses on the measurements undertaken at the JMTRC and JMTR cores. The values of excess multiplication factor are accurately determined utilizing the whole core calculation by the Monte Carlo code MCNP4A. (author)

  9. On the Determination of the Blank Shape Contour for Thin Precision Parts Obtained by Stamping

    International Nuclear Information System (INIS)

    Azaouzi, M.; Delameziere, A.; Naceur, H.; Batoz, J. L.; Sibaud, D.; Belouettar, S.

    2007-01-01

    The present study deals with the 'automatic' determination of the initial blank shape contour for 3D thin metallic precision parts obtained by stamping, knowing the 3D CAD geometry of the final part (the desired product). The forming process can involve several steps presented in this paper that consists in applying a heuristic method of optimization to find out the initial blank shape of thin precision metallic part in order to obtain a final part, with a required 3D geometry (specified). The purpose of the present approach is to replace the experimental trial and error optimization method used currently, which is expensive and time consuming. The principle of the 'heuristic' optimization method is to first estimate the blank shape using the Inverse Approach, then to compensate the shape error calculated in each node of the blank contour. The 'heuristic' optimization loop is done using a precise incremental code (Abaqus Explicit or Stampack) and, the iterations loop is stopped when the shape errors are within some initially fixed tolerances. The method is tested in the case of a special stamping process where the parts are pressed in one or more steps using a manual press, without blank holder and by the mean of tools having complex shape. The sensitivities of the process parameters regarding the optimal solution are investigated

  10. Large Eddy Simulation of Vertical Axis Wind Turbine wakes; Part II: effects of inflow turbulence

    Science.gov (United States)

    Duponcheel, Matthieu; Chatelain, Philippe; Caprace, Denis-Gabriel; Winckelmans, Gregoire

    2017-11-01

    The aerodynamics of Vertical Axis Wind Turbines (VAWTs) is inherently unsteady, which leads to vorticity shedding mechanisms due to both the lift distribution along the blade and its time evolution. Large-scale, fine-resolution Large Eddy Simulations of the flow past Vertical Axis Wind Turbines have been performed using a state-of-the-art Vortex Particle-Mesh (VPM) method combined with immersed lifting lines. Inflow turbulence with a prescribed turbulence intensity (TI) is injected at the inlet of the simulation from a precomputed synthetic turbulence field obtained using the Mann algorithm. The wake of a standard, medium-solidity, H-shaped machine is simulated for several TI levels. The complex wake development is captured in details and over long distances: from the blades to the near wake coherent vortices, then through the transitional ones to the fully developed turbulent far wake. Mean flow and turbulence statistics are computed over more than 10 diameters downstream of the machine. The sensitivity of the wake topology and decay to the TI level is assessed.

  11. Determination of carcinoembryonic antigen in patients with tumors of the large intestine

    International Nuclear Information System (INIS)

    Lamerz, R.; Ruider, H.

    1976-01-01

    Specimens from 93 patients with histologically confirmed tumors of the large bowel (53 single, 40 sequential determinations) were investigated by a new CEA radioimmunoassay (double antibody method, direct serum determination). Of the single and preoperative sequential determinations 37-40% were normal (below 2.5 ng/ml), one third was intermediately elevated (2.6 ng/ml) and 26-28% were highly pathological leveled (over 15 ng/ml). Following operation, cases with local or regionally confined tumor showed significantly more normal or normalizing CEA levels within 1-6 weeks (17/27), whereas patients with overt metastases developed more pathological or increasingly pathological levels (8/11). (orig.) [de

  12. Presence and significant determinants of cognitive impairment in a large sample of patients with multiple sclerosis.

    Directory of Open Access Journals (Sweden)

    Martina Borghi

    Full Text Available OBJECTIVES: To investigate the presence and the nature of cognitive impairment in a large sample of patients with Multiple Sclerosis (MS, and to identify clinical and demographic determinants of cognitive impairment in MS. METHODS: 303 patients with MS and 279 healthy controls were administered the Brief Repeatable Battery of Neuropsychological tests (BRB-N; measures of pre-morbid verbal competence and neuropsychiatric measures were also administered. RESULTS: Patients and healthy controls were matched for age, gender, education and pre-morbid verbal Intelligence Quotient. Patients presenting with cognitive impairment were 108/303 (35.6%. In the overall group of participants, the significant predictors of the most sensitive BRB-N scores were: presence of MS, age, education, and Vocabulary. The significant predictors when considering MS patients only were: course of MS, age, education, vocabulary, and depression. Using logistic regression analyses, significant determinants of the presence of cognitive impairment in relapsing-remitting MS patients were: duration of illness (OR = 1.053, 95% CI = 1.010-1.097, p = 0.015, Expanded Disability Status Scale score (OR = 1.247, 95% CI = 1.024-1.517, p = 0.028, and vocabulary (OR = 0.960, 95% CI = 0.936-0.984, p = 0.001, while in the smaller group of progressive MS patients these predictors did not play a significant role in determining the cognitive outcome. CONCLUSIONS: Our results corroborate the evidence about the presence and the nature of cognitive impairment in a large sample of patients with MS. Furthermore, our findings identify significant clinical and demographic determinants of cognitive impairment in a large sample of MS patients for the first time. Implications for further research and clinical practice were discussed.

  13. Single-field consistency relations of large scale structure part III: test of the equivalence principle

    Energy Technology Data Exchange (ETDEWEB)

    Creminelli, Paolo [Abdus Salam International Centre for Theoretical Physics, Strada Costiera 11, Trieste, 34151 (Italy); Gleyzes, Jérôme; Vernizzi, Filippo [CEA, Institut de Physique Théorique, Gif-sur-Yvette cédex, F-91191 France (France); Hui, Lam [Physics Department and Institute for Strings, Cosmology and Astroparticle Physics, Columbia University, New York, NY, 10027 (United States); Simonović, Marko, E-mail: creminel@ictp.it, E-mail: jerome.gleyzes@cea.fr, E-mail: lhui@astro.columbia.edu, E-mail: msimonov@sissa.it, E-mail: filippo.vernizzi@cea.fr [SISSA, via Bonomea 265, Trieste, 34136 (Italy)

    2014-06-01

    The recently derived consistency relations for Large Scale Structure do not hold if the Equivalence Principle (EP) is violated. We show it explicitly in a toy model with two fluids, one of which is coupled to a fifth force. We explore the constraints that galaxy surveys can set on EP violation looking at the squeezed limit of the 3-point function involving two populations of objects. We find that one can explore EP violations of order 10{sup −3}÷10{sup −4} on cosmological scales. Chameleon models are already very constrained by the requirement of screening within the Solar System and only a very tiny region of the parameter space can be explored with this method. We show that no violation of the consistency relations is expected in Galileon models.

  14. THREE-DIMENSIONAL DUST MAPPING REVEALS THAT ORION FORMS PART OF A LARGE RING OF DUST

    International Nuclear Information System (INIS)

    Schlafly, E. F.; Rix, H.-W.; Martin, N. F.; Green, G.; Finkbeiner, D. P.; Burgett, W. S.; Chambers, K. C.; Kaiser, N.; Morgan, J. S.; Tonry, J. L.; Wainscoat, R. J.; Waters, C.; Draper, P. W.; Metcalfe, N.; Price, P. A.

    2015-01-01

    The Orion Molecular Complex is the nearest site of ongoing high-mass star formation, making it one of the most extensively studied molecular complexes in the Galaxy. We have developed a new technique for mapping the three-dimensional distribution of dust in the Galaxy using Pan-STARRS1 photometry. We isolate the dust at the distance to Orion using this technique, revealing a large (100 pc, 14° diameter), previously unrecognized ring of dust, which we term the ''Orion dust ring''. The ring includes Orion A and B, and is not coincident with current Hα features. The circular morphology suggests formation as an ancient bubble in the interstellar medium, though we have not been able to conclusively identify the source of the bubble. This hint at the history of Orion may have important consequences for models of high-mass star formation and triggered star formation

  15. Determinants of Skilled Birth Attendance in the Northern Parts of Ghana

    Directory of Open Access Journals (Sweden)

    Kwamena Sekyi Dickson

    2017-01-01

    Full Text Available Background. An integral part of the Sustainable Development Goal three is to ensure universal access to sexual and reproductive healthcare services which include skilled delivery by the year 2030. We examined the determinants of skilled delivery among women in the Northern part of Ghana. Methods. The paper made use of data from the Demographic and Health Survey. Women from the Northern part of Ghana were included in the analysis. Bivariate descriptive analyses coupled with binary logistic regression estimation technique were used to analyse the data. Results. Region of residence, age, household wealth, education, distance to a health facility, religion, parity, partner’s education, and getting money for treatment were identified as the determinants of skilled delivery. While the probability of having a skilled delivery was higher in the Upper East Region, it was lower in the Northern and Upper West Regions compared to the Brong Ahafo Region. Conclusion. Our findings call for more attention from the Ghana Health Service and the Ministry of Health in addressing the skilled delivery gaps among women particularly in the Northern and Upper West Regions in ensuring attainment of the Sustainable Development Goal target related to reproductive health care accessibility for all by the year 2030.

  16. The interannual precipitation variability in the southern part of Iran as linked to large-scale climate modes

    Energy Technology Data Exchange (ETDEWEB)

    Pourasghar, Farnaz; Jahanbakhsh, Saeed; Sari Sarraf, Behrooz [The University of Tabriz, Department of Physical Geography, Faculty of Humanities and Social Science, Tabriz (Iran, Islamic Republic of); Tozuka, Tomoki [The University of Tokyo, Department of Earth and Planetary Science, Graduate School of Science, Tokyo (Japan); Ghaemi, Hooshang [Iran Meteorological Organization, Tehran (Iran, Islamic Republic of); Yamagata, Toshio [The University of Tokyo, Department of Earth and Planetary Science, Graduate School of Science, Tokyo (Japan); Application Laboratory/JAMSTEC, Yokohama, Kanagawa (Japan)

    2012-11-15

    The interannual variation of precipitation in the southern part of Iran and its link with the large-scale climate modes are examined using monthly data from 183 meteorological stations during 1974-2005. The majority of precipitation occurs during the rainy season from October to May. The interannual variation in fall and early winter during the first part of the rainy season shows apparently a significant positive correlation with the Indian Ocean Dipole (IOD) and El Nino-Southern Oscillation (ENSO). However, a partial correlation analysis used to extract the respective influence of IOD and ENSO shows a significant positive correlation only with the IOD and not with ENSO. The southeasterly moisture flux anomaly over the Arabian Sea turns anti-cyclonically and transport more moisture to the southern part of Iran from the Arabian Sea, the Red Sea, and the Persian Gulf during the positive IOD. On the other hand, the moisture flux has northerly anomaly over Iran during the negative IOD, which results in reduced moisture supply from the south. During the latter part of the rainy season in late winter and spring, the interannual variation of precipitation is more strongly influenced by modes of variability over the Mediterranean Sea. The induced large-scale atmospheric circulation anomaly controls moisture supply from the Red Sea and the Persian Gulf. (orig.)

  17. A large-scale soil-structure interaction experiment: Part I design and construction

    International Nuclear Information System (INIS)

    Tang, H.T.; Tang, Y.K.; Wall, I.B.; Lin, E.

    1987-01-01

    In the simulated earthquake experiments (SIMQUAKE) sponsored by EPRI, the detonation of vertical arrays of explosives propagated wave motions through the ground to the model structures. Although such a simulation can provide information about dynamic soil-structure interaction (SSI) characteristics in a strong motion environment, it lacks seismic wave scattering characteristics for studying seismic input to the soil-structure system and the effect of different kinds of wave composition to the soil-structure response. To supplement the inadequacy of the simulated earthquake SSI experiment, the Electric Power Research Institute (EPRI) and the Taiwan Power Company (Taipower) jointly sponsored a large scale SSI experiment in the field. The objectives of the experiment are: (1) to obtain actual strong motion earthquakes induced database in a soft-soil environment which will substantiate predictive and design SSI models;and (2) to assess nuclear power plant reactor containment internal components dynamic response and margins relating to actual earthquake-induced excitation. These objectives are accomplished by recording and analyzing data from two instrumented, scaled down, (1/4- and 1/12-scale) reinforced concrete containments sited in a high seismic region in Taiwan where a strong-motion seismic array network is located

  18. Determination of Solution Accuracy of Numerical Schemes as Part of Code and Calculation Verification

    Energy Technology Data Exchange (ETDEWEB)

    Blottner, F.G.; Lopez, A.R.

    1998-10-01

    This investigation is concerned with the accuracy of numerical schemes for solving partial differential equations used in science and engineering simulation codes. Richardson extrapolation methods for steady and unsteady problems with structured meshes are presented as part of the verification procedure to determine code and calculation accuracy. The local truncation error de- termination of a numerical difference scheme is shown to be a significant component of the veri- fication procedure as it determines the consistency of the numerical scheme, the order of the numerical scheme, and the restrictions on the mesh variation with a non-uniform mesh. Genera- tion of a series of co-located, refined meshes with the appropriate variation of mesh cell size is in- vestigated and is another important component of the verification procedure. The importance of mesh refinement studies is shown to be more significant than just a procedure to determine solu- tion accuracy. It is suggested that mesh refinement techniques can be developed to determine con- sistency of numerical schemes and to determine if governing equations are well posed. The present investigation provides further insight into the conditions and procedures required to effec- tively use Richardson extrapolation with mesh refinement studies to achieve confidence that sim- ulation codes are producing accurate numerical solutions.

  19. Shock and vibration environments for a large shipping container during truck transport (Part II)

    International Nuclear Information System (INIS)

    Magnuson, C.E.

    1978-05-01

    Purpose of this study was to obtain vibration and shock data during truck shipment of heavy cargo. These data were for use in determining any trends of vibration and shock environments with increased cargo weight. The new data were obtained on a ''piggyback'' basis during truck transport of 249 100N (56,000-pound) cargo which consisted of a spent fuel container and its supporting structure. The truck was driven from Mercury, Nevada, to Albuquerque, New Mexico. The routes traveled were US 95 from Mercury, Nevada, to Las Vegas, Nevada; US 93 from Las Vegas to Kingman, Arizona; and I-40/US 66 from Kingman to Albuquerque, New Mexico. Speeds varied from very slow to 88 km/hr (55 mph). A comparison of data from similar experiments with cargo weights varying from no-load to this load shows that the zero-to-peak acceleration amplitude levels of vibration are highest when trucks carry relatively light loads. This is true for the longitudinal and vertical axes of the vehicles in most frequency bands and for the transverse axis above 700 Hz. The shock response acceleration amplitudes for heavier cargo weights were less severe above 3 Hz in the vertical axis and higher between 8 and 20 Hz in the transverse axis. The highest acceleration amplitude of shock response in the longitudinal axis below about 20 Hz was produced in a trailer having a spring suspension system and carrying the 249 100N (56,000 pounds) load

  20. Development of a Lunar Scintillometer as part of the national large optical telescope site survey

    Science.gov (United States)

    Surendran, Avinash; Parihar, Padmakar S.; Banyal, Ravinder K.; Kalyaan, Anusha

    2018-03-01

    Ground layer turbulence is a very important site characterization parameter used to assess the quality of an astronomical site. The Lunar Scintillometer is a simple and effective site-testing device for measuring the ground layer turbulence. It consists of a linear array of photodiodes which are sensitive to the slight variations in the moon's brightness due to scintillation by the lower layers of the Earth's atmosphere. The covariance of intensity values between the non-redundant photodiode baselines can be used to measure the turbulence profile from the ground up to a height determined by the furthest pair of detectors. The six channel lunar scintillometer that has been developed at the Indian Institute of Astrophysics is based closely on an instrument built by the team led by Andrei Tokovinin of Cerro Tololo Inter-American Observatory (CTIO), Chile (Tokovinin et al., Mon. Not. R. Astron. Soc. 404(3), 1186-1196 2010). We have fabricated the instrument based on the existing electronic design, and have worked on the noise analysis, an EMI (Electromagnetic Induction) resistant PCB design and the software pipeline for analyzing the data from the same. The results from the instrument's multi-year campaign at Mount Saraswati, Hanle is also presented.

  1. On the accuracy of protein determination in large biological samples by prompt gamma neutron activation analysis

    Energy Technology Data Exchange (ETDEWEB)

    Kasviki, K. [Institute of Nuclear Technology and Radiation Protection, NCSR ' Demokritos' , Aghia Paraskevi, Attikis 15310 (Greece); Medical Physics Laboratory, Medical School, University of Ioannina, Ioannina 45110 (Greece); Stamatelatos, I.E. [Institute of Nuclear Technology and Radiation Protection, NCSR ' Demokritos' , Aghia Paraskevi, Attikis 15310 (Greece)], E-mail: ion@ipta.demokritos.gr; Yannakopoulou, E. [Institute of Physical Chemistry, NCSR ' Demokritos' , Aghia Paraskevi, Attikis 15310 (Greece); Papadopoulou, P. [Institute of Technology of Agricultural Products, NAGREF, Lycovrissi, Attikis 14123 (Greece); Kalef-Ezra, J. [Medical Physics Laboratory, Medical School, University of Ioannina, Ioannina 45110 (Greece)

    2007-10-15

    A prompt gamma neutron activation analysis (PGNAA) facility has been developed for the determination of nitrogen and thus total protein in large volume biological samples or the whole body of small animals. In the present work, the accuracy of nitrogen determination by PGNAA in phantoms of known composition as well as in four raw ground meat samples of about 1 kg mass was examined. Dumas combustion and Kjeldahl techniques were also used for the assessment of nitrogen concentration in the meat samples. No statistically significant differences were found between the concentrations assessed by the three techniques. The results of this work demonstrate the applicability of PGNAA for the assessment of total protein in biological samples of 0.25-1.5 kg mass, such as a meat sample or the body of small animal even in vivo with an equivalent radiation dose of about 40 mSv.

  2. On the accuracy of protein determination in large biological samples by prompt gamma neutron activation analysis

    International Nuclear Information System (INIS)

    Kasviki, K.; Stamatelatos, I.E.; Yannakopoulou, E.; Papadopoulou, P.; Kalef-Ezra, J.

    2007-01-01

    A prompt gamma neutron activation analysis (PGNAA) facility has been developed for the determination of nitrogen and thus total protein in large volume biological samples or the whole body of small animals. In the present work, the accuracy of nitrogen determination by PGNAA in phantoms of known composition as well as in four raw ground meat samples of about 1 kg mass was examined. Dumas combustion and Kjeldahl techniques were also used for the assessment of nitrogen concentration in the meat samples. No statistically significant differences were found between the concentrations assessed by the three techniques. The results of this work demonstrate the applicability of PGNAA for the assessment of total protein in biological samples of 0.25-1.5 kg mass, such as a meat sample or the body of small animal even in vivo with an equivalent radiation dose of about 40 mSv

  3. Three-dimensional nanostructure determination from a large diffraction data set recorded using scanning electron nanodiffraction

    Directory of Open Access Journals (Sweden)

    Yifei Meng

    2016-09-01

    Full Text Available A diffraction-based technique is developed for the determination of three-dimensional nanostructures. The technique employs high-resolution and low-dose scanning electron nanodiffraction (SEND to acquire three-dimensional diffraction patterns, with the help of a special sample holder for large-angle rotation. Grains are identified in three-dimensional space based on crystal orientation and on reconstructed dark-field images from the recorded diffraction patterns. Application to a nanocrystalline TiN thin film shows that the three-dimensional morphology of columnar TiN grains of tens of nanometres in diameter can be reconstructed using an algebraic iterative algorithm under specified prior conditions, together with their crystallographic orientations. The principles can be extended to multiphase nanocrystalline materials as well. Thus, the tomographic SEND technique provides an effective and adaptive way of determining three-dimensional nanostructures.

  4. Determinants of injuries and Road Traffic Accidents amongst service personnel in a large Defence station.

    Science.gov (United States)

    Neelakantan, Anand; Kotwal, Brig Atul; Ilankumaran, Mookkiah

    2017-07-01

    Injuries are assuming epidemic proportions globally; and in India. Also, previous decade witnessed carnage on Indian roads, with nearly 12 lakh people killed and 55 lakhs disabled in road crashes. The trend in Armed Forces is reflective of the aforesaid patterns. Behaviour and socio-demographic background of the victims are significant determinants of injuries and road accidents. Community-based epidemiological information on these aspects is envisaged to contribute in their preventive strategy. Towards this direction, the present study was conducted with aim to generate socio-behavioural profile of injuries and Road Traffic Accidents (RTAs) amongst service personnel in a large defence station; and to evaluate their determinants. A cross sectional descriptive study was carried out among 796 Naval personnel onboard warships in large Naval station. Data on socio-behavioural aspects and determinants of injuries and road accidents was collected using a pre-validated questionnaire; and by scrutiny of relevant records. Data was analysed using MSExcel, Epi-info and SPSS 17. Young and middle-aged persons were predominantly involved in injuries and road accidents. Two-wheeler users sustained maximum road accidents. Human factor was a significant determinant in RTAs and injuries. A majority of victims admitted that human factors were the predominant cause of road accidents; and opined that the events were preventable. Age-specific Behavioural Change Communication strategies aimed at refining user outlook are imperative; tailored to sociodemographic milieu of user/victim. Incorporation of a dynamic feedback/reporting mechanism, creation of 'armed forces-specific road safety and injury prevention policy' and safety audits on injuries and road crashes are measures in this direction.

  5. Nuclear fuel technology - Tank calibration and volume determination for nuclear materials accountancy - Part 1: Procedural overview

    International Nuclear Information System (INIS)

    2007-01-01

    Accurate determinations of volume are a fundamental component of any measurement-based system of control and accountability in a facility that processes or stores nuclear materials in liquid form. Volume determinations are typically made with the aid of a calibration or volume measurement equation that relates the response of the tank's measurement system to some independent measure of tank volume. The ultimate purpose of the calibration exercise is to estimate the tank's volume measurement equation (the inverse of the calibration equation), which relates tank volume to measurement system response. The steps carried out to acquire data for estimating the tank's calibration or volume measurement equation are collectively described as the process of tank calibration. This part of ISO 18213 describes procedures for tank calibration and volume determination for nuclear process tanks equipped with pressure-measurement systems for determining liquid content. Specifically, overall guidance is provided for planning a calibration exercise undertaken to obtain the data required for the measurement equation to estimate a tank's volume. The key steps in the procedure are also presented for subsequently using the estimated volume-measurement equation to determine tank liquid volumes. The procedures presented apply specifically to tanks equipped with bubbler probe systems for measuring liquid content. Moreover, these procedures produce reliable results only for clear (i.e. without suspended solids), homogeneous liquids that are at both thermal and static equilibrium. The paper elaborates on scope, physical principles involved, the calibration model, equipment required, a typical tank calibration procedure, calibration planning and pre-calibration activities, and volume determination. A bibliography is provided

  6. Tissue Distribution of a Therapeutic Monoclonal Antibody Determined by Large Pore Microdialysis.

    Science.gov (United States)

    Jadhav, Satyawan B; Khaowroongrueng, Vipada; Fueth, Matthias; Otteneder, Michael B; Richter, Wolfgang; Derendorf, Hartmut

    2017-09-01

    Therapeutic monoclonal antibodies (mAbs) exhibit limited distribution to the target tissues. Determination of target tissue interstitial concentration of mAbs is an important aspect in the assessment of their pharmacokinetic/pharmacodynamics relationship especially for mAbs targeting membrane bound receptors. The pharmacokinetics of R7072, a full length mAb (IgG) targeting human insulin-like growth factor-1 receptor was evaluated following a single intravenous dose at 1, 6.25, and 25 mg/kg in healthy female SCID-beige mice. R7072 showed linear pharmacokinetics over the dose range tested and was characterized by low systemic clearance and long terminal half-life. Furthermore, interstitial distribution of R7072 was evaluated in liver, skin, kidney, and muscle tissues using large pore microdialysis (MD) after intravenous administration of 10 mg/kg dose in mice. The relative recoveries of R7072 were consistent and similar between in vitro and in vivo MD experiments. The tissue and interstitial concentrations were significantly lower compared to serum concentrations and found to be highest in liver and lowest in muscle. The interstitial concentrations of R7072 were approximately 2-fold to 4-fold lower than corresponding total tissue concentrations. Large pore MD appears to be an attractive approach for direct measurement of pharmacologically relevant concentrations of therapeutic mAbs in tissue interstitial fluid. Copyright © 2017 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

  7. Amino acids analysis by total neutron cross-sections determinations: part V

    International Nuclear Information System (INIS)

    Voi, Dante L.; Ferreira, Francisco de O.; Rocha, Helio F. da

    2013-01-01

    Total neutron cross-sections of twenty essential and non-essential amino acids to human were determined using crystal spectrometer installed on the Argonauta reactor of IEN (Instituto de Engenharia Nuclear (CNEN-RJ) and compared with data generated by parceling and grouping methodologies developed at this institution. For each amino acid was calculated the respective neutron cross-section by molecular structure, conformation and chemistry analysis. The results obtained for eighteen of twenty amino acids confirm the specifications and product formulations indicated by manufactures. These initial results allow to build a neutron cross-sections database as part of quality control of the amino supplied to hospitals for production of nutriments for parenteral or enteral formulations used in critical patients dependent on artificial feed, and for application in future studies of structure and dynamics for more complex molecules, including proteins, enzymes, fatty acids, membranes, organelles and other cell components. (author)

  8. Clinical picture and treatment of complications of lower part of large intestine resulting from radiotherapy for intra-pelvic cancer

    International Nuclear Information System (INIS)

    Ikeda, Yoshihito; Sunagawa, Keishin; Matsumura, Shigejiro; Watanabe, Kenji; Masaoka, Yoshio

    1976-01-01

    The authors described clinical pictures and those treatments of 40 patients with complications of the lower part of the large intestine resulting from radiotherapy for cancer of the uterus, ovarium or the penis. As the radiotherapy, 60 Co-telecobalt (6,000-16,000R) and 60 Co-needle (1,000-8,568 mch) intracavitary irradiation were used alone or in combination. Findings in the complications of the lower part of the large intestine were classified into Grade I (13 cases), II (14), III (14), and IV (4) according to Sherman. The prodromal symptoms of the complications appeared in 2-6 months following the irradiation in more than a half of the patients, and it appeared within a year in most of the patients. Most of the patients complained about melena, anemia, proctagra, tenesmus and diarrhea. In the cases of Grade III, the symptoms of ileus such as constipation, abdominal distention, and abdominal pain appeared. Internal treatment was given principally, and preternal anus was made when frequent blood transfusion was required. Fourteen cases of those in Grade I and II recovered within 1-3 years. The cases which received proctostomy, including those who had bleeding, stricture and fistulation, had favorable prognosis. This result suggested that the radiotherapy for intra-pelvic cancer should be controlled to prevent further development of the complications in the rectum beyond Grade I. (Serizawa, K.)

  9. A new method to determine large scale structure from the luminosity distance

    International Nuclear Information System (INIS)

    Romano, Antonio Enea; Chiang, Hsu-Wen; Chen, Pisin

    2014-01-01

    The luminosity distance can be used to determine the properties of large scale structure around the observer. To this purpose we develop a new inversion method to map luminosity distance to a Lemaitre–Tolman–Bondi (LTB) metric based on the use of the exact analytical solution for Einstein equations. The main advantages of this approach are an improved numerical accuracy and stability, an exact analytical setting of the initial conditions for the differential equations which need to be solved and the validity for any sign of the functions determining the LTB geometry. Given the fully analytical form of the differential equations, this method also simplifies the calculation of the red-shift expansion around the apparent horizon point where the numerical solution becomes unstable. We test the method by inverting the supernovae Ia luminosity distance function corresponding to the best fit ΛCDM model. We find that only a limited range of initial conditions is compatible with observations, or a transition from red to blue-shift can occur at relatively low red-shift. Despite LTB solutions without a cosmological constant have been shown not to be compatible with all different set of available observational data, those studies normally fit data assuming a special functional ansatz for the inhomogeneity profile, which often depend only on few parameters. Inversion methods on the contrary are able to fully explore the freedom in fixing the functions which determine a LTB solution. Another important possible application is not about LTB solutions as cosmological models, but rather as tools to study the effects on the observations made by a generic observer located in an inhomogeneous region of the Universe where a fully non perturbative treatment involving exact solutions of Einstein equations is required. (paper)

  10. The Methodology Applied in DPPH, ABTS and Folin-Ciocalteau Assays Has a Large Influence on the Determined Antioxidant Potential.

    Science.gov (United States)

    Abramovič, Helena; Grobin, Blaž; Poklar, Nataša; Cigić, Blaž

    2017-06-01

    Antioxidant potential (AOP) is not only the property of the matrix analyzed but also depends greatly on the methodology used. The chromogenic radicals 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS•+), 2,2-diphenyl-1-picrylhydrazyl (DPPH•) and Folin-Ciocalteu (FC) assay were applied to estimate how the method and the composition of the assay solvent influence the AOP determined for coffee, tea, beer, apple juice and dietary supplements. Large differences between the AOP values depending on the reaction medium were observed, with the highest AOP determined mostly in the FC assay. In reactions with chromogenic radicals several fold higher values of AOP were obtained in buffer pH 7.4 than in water or methanol. The type of assay and solvent composition have similar influences on the reactivity of a particular antioxidant, either pure or as part of a complex matrix. The reaction kinetics of radicals with antioxidants in samples reveals that AOP depends strongly on incubation time, yet differently for each sample analyzed and the assay applied.

  11. Globalization and social determinants of health: Introduction and methodological background (part 1 of 3)

    Science.gov (United States)

    Labonté, Ronald; Schrecker, Ted

    2007-01-01

    Globalization is a key context for the study of social determinants of health (SDH). Broadly stated, SDH are the conditions in which people live and work, and that affect their opportunities to lead healthy lives. In this first article of a three-part series, we describe the origins of the series in work conducted for the Globalization Knowledge Network of the World Health Organization's Commission on Social Determinants of Health and in the Commission's specific concern with health equity. We explain our rationale for defining globalization with reference to the emergence of a global marketplace, and the economic and political choices that have facilitated that emergence. We identify a number of conceptual milestones in studying the relation between globalization and SDH over the period 1987–2005, and then show that because globalization comprises multiple, interacting policy dynamics, reliance on evidence from multiple disciplines (transdisciplinarity) and research methodologies is required. So, too, is explicit recognition of the uncertainties associated with linking globalization – the quintessential "upstream" variable – with changes in SDH and in health outcomes. PMID:17578568

  12. DETERMINING UNDISTURBED GROUND TEMPERATURE AS PART OF SHALLOW GEOTHERMAL RESOURCES ASSESSMENT

    Directory of Open Access Journals (Sweden)

    Tomislav Kurevija

    2010-12-01

    Full Text Available The undisturbed ground temperature is one of the key thermogeological parameters for the assessment and utilization of shallow geothermal resources. Geothermal energy is the type of energy which is stored in the ground where solar radiation has no effect. The depth at which the undisturbed ground temperature occurs, independent of seasonal changes in the surface air temperature, is functionally determined by climate parameters and thermogeological properties. In deeper layers, the increase of ground temperature depends solely on geothermal gradient. Determining accurate values of undisturbed ground temperature and depth of occurrence is crucial for the correct sizing of a borehole heat exchanger as part of the ground-source heat pump system, which is considered the most efficient technology for utilising shallow geothermal resources. The purpose of this paper is to define three specific temperature regions, based on the measured ground temperature data collected from the main meteorological stations in Croatia. The three regions are: Northern Croatia, Adriatic region, and the regions of Lika and Gorski Kotar.

  13. Globalization and social determinants of health: The role of the global marketplace (part 2 of 3

    Directory of Open Access Journals (Sweden)

    Schrecker Ted

    2007-06-01

    Full Text Available Abstract Globalization is a key context for the study of social determinants of health (SDH: broadly stated, SDH are the conditions in which people live and work, and that affect their opportunities to lead healthy lives. In the first article in this three part series, we described the origins of the series in work conducted for the Globalization Knowledge Network of the World Health Organization's Commission on Social Determinants of Health and in the Commission's specific concern with health equity. We identified and defended a definition of globalization that gives primacy to the drivers and effects of transnational economic integration, and addressed a number of important conceptual and methodological issues in studying globalization's effects on SDH and their distribution, emphasizing the need for transdisciplinary approaches that reflect the complexity of the topic. In this second article, we identify and describe several, often interacting clusters of pathways leading from globalization to changes in SDH that are relevant to health equity. These involve: trade liberalization; the global reorganization of production and labour markets; debt crises and economic restructuring; financial liberalization; urban settings; influences that operate by way of the physical environment; and health systems changed by the global marketplace.

  14. 75 FR 14126 - Amended Final Determination of Sales at Less Than Fair Value: Diamond Sawblades and Parts Thereof...

    Science.gov (United States)

    2010-03-24

    ... of Sales at Less Than Fair Value: Diamond Sawblades and Parts Thereof From the Republic of Korea... Department'') published its notice of final determination of sales at less than fair value (``LTFV'') in the... Notice of Final Determination of Sales at Less Than Fair Value and Final Determination of Critical...

  15. Making mental health an integral part of sustainable development: the contribution of a social determinants framework.

    Science.gov (United States)

    De Silva, M J

    2015-04-01

    There have been repeated calls to include mental health in the sustainable development goals (SDGs), arguing that progress in development will not be made without improvements in mental health. Although these calls are starting to gain political traction, currently only a tiny fraction of international development work includes mental health. A social determinants framework may be useful in incorporating mental health into sustainable development because it promotes a multi-sectorial and multi-disciplinary approach which is the corner stone of good development practice. Two approaches are suggested to make mental health a part of sustainable development: (1) integrate mental health into existing development programmes to promote social and economic environments that prevent mental health problems developing; (2) ensure that mental health programmes are better at promoting sustainable development by preventing the negative social and economic consequences of mental illness. Real-world examples of these approaches are provided. To achieve this, the mental health impact of wider development programmes, and the social and economic consequences of mental health interventions, must be evaluated. Development agencies should ensure that they have equity for mental health in all their policies, and investment must be increased for those mental health prevention, promotion and treatment programmes which have the greatest impact on sustainable development. The SDGs bring the promise of a more holistic approach to development. It is now the task of global mental health to demonstrate not just that mental health is an integral part of sustainable development, but that affordable and effective solutions exist which can improve mental health and development more broadly.

  16. Data-Mining Toolset Developed for Determining Turbine Engine Part Life Consumption

    Science.gov (United States)

    Litt, Jonathan S.

    2003-01-01

    The current practice in aerospace turbine engine maintenance is to remove components defined as life-limited parts after a fixed time, on the basis of a predetermined number of flight cycles. Under this schedule-based maintenance practice, the worst-case usage scenario is used to determine the usable life of the component. As shown, this practice often requires removing a part before its useful life is fully consumed, thus leading to higher maintenance cost. To address this issue, the NASA Glenn Research Center, in a collaborative effort with Pratt & Whitney, has developed a generic modular toolset that uses data-mining technology to parameterize life usage models for maintenance purposes. The toolset enables a "condition-based" maintenance approach, where parts are removed on the basis of the cumulative history of the severity of operation they have experienced. The toolset uses data-mining technology to tune life-consumption models on the basis of operating and maintenance histories. The flight operating conditions, represented by measured variables within the engine, are correlated with repair records for the engines, generating a relationship between the operating condition of the part and its service life. As shown, with the condition-based maintenance approach, the lifelimited part is in service until its usable life is fully consumed. This approach will lower maintenance costs while maintaining the safety of the propulsion system. The toolset is a modular program that is easily customizable by users. First, appropriate parametric damage accumulation models, which will be functions of engine variables, must be defined. The tool then optimizes the models to match the historical data by computing an effective-cycle metric that reduces the unexplained variability in component life due to each damage mode by accounting for the variability in operational severity. The damage increment due to operating conditions experienced during each flight is used to compute

  17. Anza palaeoichnological site. Late Cretaceous. Morocco. Part II. Problems of large dinosaur trackways and the first African Macropodosaurus trackway

    Science.gov (United States)

    Masrour, Moussa; Lkebir, Noura; Pérez-Lorente, Félix

    2017-10-01

    The Anza site shows large ichnological surfaces indicating the coexistence in the same area of different vertebrate footprints (dinosaur and pterosaur) and of different types (tridactyl and tetradactyl, semiplantigrade and rounded without digit marks) and the footprint variability of long trackways. This area may become a world reference in ichnology because it contains the second undebatable African site with Cretaceous pterosaur footprints - described in part I - and the first African site with Macropodosaurus footprints. In this work, problems related to long trackways are also analyzed, such as their sinuosity, the order-disorder of the variability (long-short) of the pace length and the difficulty of morphological classification of the theropod footprints due to their morphological variability.

  18. A Survey of Optometry Graduates to Determine Practice Patterns: Part II: Licensure and Practice Establishment Experiences.

    Science.gov (United States)

    Bleimann, Robert L.; Smith, Lee W.

    1985-01-01

    A summary of Part II of a two-volume study of optometry graduates conducted by the Association of Schools and Colleges of Optometry is presented. Part II includes the analysis of the graduates' licensure and practice establishment experiences. (MLW)

  19. Determination of total triterpenoid acids in different part and extract of Ganoderma lucidum

    Directory of Open Access Journals (Sweden)

    FENG Huiqin

    2013-04-01

    Full Text Available Aim To develop a method for determination of total triterpenoid acids in different part and extracts of Ganoderma lucidum. Method The samples of Ganoderma lucidum were extracted with ethanol and successively extracted with CHCl3 and 5% NaHCO3,the NaHCO3 layer was acidified to pH 3 with 2 mol/L HCl,the resulting precipitates were dissolved in CHCl3 and evaporated in vacuo then weighed. The total triterpenoid acids were obtained. Result The total triterpenoid acids of Ganoderma lucidum fruitbody,spore and mycelium were (8.58±0.25 mg/g,(3.48±0.03 mg/g and (1.75 ±0.09 mg/g respectively. The total triterpenoid acids of pileus and stipe were (12.62±0.22 mg/g and (7.66±0.08 mg/g. The range of total triterpenoid acid content among 10 batches of Ganoderma lucidum fruitbody purchased from the market was between 4.34 to 16.39 mg/g. The highest content fro/8/8/88/ m Ganoderma lucidum fruiting body with alcohol - water extracting was (208.70±5.54 mg/g and the lowest content with alkaline solution extracting was (123.07±4.99 mg/g. The composition of total triterpenoid acid from fruitbody,spores and extract of fruitbody analyzed by HPLC were almost the same. This method is reliable for determination of total triterpenoid acid in the fruiting body and its extracts,spore and mycelium from Ganoderma lucidum,which provides an indicator for the quality of Ganoderma lucidum product.

  20. 20 CFR 30.801 - What special definitions does OWCP use in connection with Part E wage-loss determinations?

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false What special definitions does OWCP use in connection with Part E wage-loss determinations? 30.801 Section 30.801 Employees' Benefits OFFICE OF WORKERS... paying compensation based on wage-loss under Part E of the Act, OWCP will apply the following definitions...

  1. 19 CFR Appendix C to Part 113 - Bond for Deferral of Duty on Large Yachts Imported for Sale at United States Boat Shows

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Bond for Deferral of Duty on Large Yachts Imported... Appendix C to Part 113—Bond for Deferral of Duty on Large Yachts Imported for Sale at United States Boat Shows Bond for Deferral of Duty on Large Yachts Imported for Sale at United States Boat Shows ____, as...

  2. 76 FR 76146 - Large Power Transformers From the Republic of Korea: Postponement of Preliminary Determination of...

    Science.gov (United States)

    2011-12-06

    ... DEPARTMENT OF COMMERCE International Trade Administration [A-580-867] Large Power Transformers... initiation of the antidumping duty investigation of large power transformers from the Republic of Korea (Korea). See Large Power Transformers from the Republic of Korea: Initiation of Antidumping Duty...

  3. Experimental determination of the energy efficiency of an air-cooled chiller under part load conditions

    International Nuclear Information System (INIS)

    Yu, F.W.; Chan, K.T.

    2005-01-01

    In cities located in a subtropical climate, air-cooled chillers are commonly used to provide cooling to the indoor environment. This accounts for the increasing electricity demand of buildings over the decades. This paper investigates how the condensing temperature serves to accurately determine the energy efficiency, or coefficient of performance (COP), of air-cooled chillers under part load conditions. An experiment on an air-cooled reciprocating chiller showed that for any given operating condition, the COP of the chiller varies, depending on how the condensing temperature is controlled. A sensitivity analysis is implemented to investigate to what extent COP is responding to changes in operating variables and confirms that the condensing temperature is an adequate variable to gauge COP under various operating conditions. The specifications of the upper limit for the condensing temperature in order to improve the energy efficiency of air-cooled chillers are discussed. The results of this work will give designers and researchers a good idea about how to model chiller energy performance curves in the thermal and energy computation exercises

  4. The non-peptidic part determines the internalization mechanism and intracellular trafficking of peptide amphiphiles.

    Directory of Open Access Journals (Sweden)

    Dimitris Missirlis

    Full Text Available BACKGROUND: Peptide amphiphiles (PAs are a class of amphiphilic molecules able to self-assemble into nanomaterials that have shown efficient in vivo targeted delivery. Understanding the interactions of PAs with cells and the mechanisms of their internalization and intracellular trafficking is critical in their further development for therapeutic delivery applications. METHODOLOGY/PRINCIPAL FINDINGS: PAs of a novel, cell- and tissue-penetrating peptide were synthesized possessing two different lipophilic tail architectures and their interactions with prostate cancer cells were studied in vitro. Cell uptake of peptides was greatly enhanced post-modification. Internalization occurred via lipid-raft mediated endocytosis and was common for the two analogs studied. On the contrary, we identified the non-peptidic part as the determining factor of differences between intracellular trafficking and retention of PAs. PAs composed of di-stearyl lipid tails linked through poly(ethylene glycol to the peptide exhibited higher exocytosis rates and employed different recycling pathways compared to ones consisting of di-palmitic-coupled peptides. As a result, cell association of the former PAs decreased with time. CONCLUSIONS/SIGNIFICANCE: Control over peptide intracellular localization and retention is possible by appropriate modification with synthetic hydrophobic tails. We propose this as a strategy to design improved peptide-based delivery systems.

  5. A methodology for fault diagnosis in large chemical processes and an application to a multistage flash desalination process: Part I

    International Nuclear Information System (INIS)

    Tarifa, Enrique E.; Scenna, Nicolas J.

    1998-01-01

    This work presents a new strategy for fault diagnosis in large chemical processes (E.E. Tarifa, Fault diagnosis in complex chemistries plants: plants of large dimensions and batch processes. Ph.D. thesis, Universidad Nacional del Litoral, Santa Fe, 1995). A special decomposition of the plant is made in sectors. Afterwards each sector is studied independently. These steps are carried out in the off-line mode. They produced vital information for the diagnosis system. This system works in the on-line mode and is based on a two-tier strategy. When a fault is produced, the upper level identifies the faulty sector. Then, the lower level carries out an in-depth study that focuses only on the critical sectors to identify the fault. The loss of information produced by the process partition may cause spurious diagnosis. This problem is overcome at the second level using qualitative simulation and fuzzy logic. In the second part of this work, the new methodology is tested to evaluate its performance in practical cases. A multiple stage flash desalination system (MSF) is chosen because it is a complex system, with many recycles and variables to be supervised. The steps for the knowledge base generation and all the blocks included in the diagnosis system are analyzed. Evaluation of the diagnosis performance is carried out using a rigorous dynamic simulator

  6. On the architecture for the X part of a very large FX correlator using two-accumulator CMACs

    Science.gov (United States)

    Lapshev, Stepan; Rezaul Hasan, S. M.

    2016-02-01

    This paper presents an improved input-buffer architecture for the X part of a very large FX correlator that optimizes memory use to both increase performance and reduce the overall power consumption. The architecture uses an array of two-accumulator CMACs that are reused for different pairs of correlated signals. Using two accumulators in every CMAC allows the processing array to alternately correlate two sets of signal pairs selected in such a way so that they share some or all of the processed data samples. This leads to increased processing bandwidth and a significant reduction of the memory read rate due to not having to update some or all of the processing buffers in every second processing cycle. The overall memory access rate is at most 75 % of that of the single-accumulator CMAC array. This architecture is intended for correlators of very large multi-element radio telescopes such as the Square Kilometre Array (SKA), and is suitable for an ASIC implementation.

  7. A methodology for fault diagnosis in large chemical processes and an application to a multistage flash desalination process: Part II

    International Nuclear Information System (INIS)

    Tarifa, Enrique E.; Scenna, Nicolas J.

    1998-01-01

    In Part I, an efficient method for identifying faults in large processes was presented. The whole plant is divided into sectors by using structural, functional, or causal decomposition. A signed directed graph (SDG) is the model used for each sector. The SDG represents interactions among process variables. This qualitative model is used to carry out qualitative simulation for all possible faults. The output of this step is information about the process behaviour. This information is used to build rules. When a symptom is detected in one sector, its rules are evaluated using on-line data and fuzzy logic to yield the diagnosis. In this paper the proposed methodology is applied to a multiple stage flash (MSF) desalination process. This process is composed of sequential flash chambers. It was designed for a pilot plant that produces drinkable water for a community in Argentina; that is, it is a real case. Due to the large number of variables, recycles, phase changes, etc., this process is a good challenge for the proposed diagnosis method

  8. The technique of express vital determination of radiocesium specific activity in muscular tissue of large agricultural animals by means of the TIM-140 radiometer

    International Nuclear Information System (INIS)

    1997-01-01

    The technique is intended for vital determination of cesium 137 specific activity in muscular tissue of large agricultural animals by means of the TIM-140 radiometer. The specific activity is determined using two measurements. With one measurement the gamma radiation detector is located on a lateral surface of coxofemoral part of the animal, and with the second measurement the absorbing gamma radiation screen is placed between the detector and zone of measurement. The external gamma background and useful signal are registered simultaneously. It allows to carry out measurements with a background till 0.05 mR/h without application of external screens

  9. Method to Determine Appropriate Source Models of Large Earthquakes Including Tsunami Earthquakes for Tsunami Early Warning in Central America

    OpenAIRE

    Tanioka, Yuichiro; Miranda, Greyving Jose Arguello; Gusman, Aditya Riadi; Fujii, Yushiro

    2017-01-01

    Large earthquakes, such as the Mw 7.7 1992 Nicaragua earthquake, have occurred off the Pacific coasts of El Salvador and Nicaragua in Central America and have generated distractive tsunamis along these coasts. It is necessary to determine appropriate fault models before large tsunamis hit the coast. In this study, first, fault parameters were estimated from the W-phase inversion, and then an appropriate fault model was determined from the fault parameters and scaling relationships with a dept...

  10. Determinants of Functional and Structural Properties of Large Arteries in Healthy Individuals

    Energy Technology Data Exchange (ETDEWEB)

    Tolezani, Elaine Cristina; Costa-Hong, Valéria, E-mail: hong.valeria@gmail.com; Correia, Gustavo; Mansur, Alfredo José; Drager, Luciano Ferreira; Bortolotto, Luiz Aparecido [Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP (Brazil)

    2014-11-15

    Changes in the properties of large arteries correlate with higher cardiovascular risk. Recent guidelines have included the assessment of those properties to detect subclinical disease. Establishing reference values for the assessment methods as well as determinants of the arterial parameters and their correlations in healthy individuals is important to stratify patients. To assess, in healthy adults, the distribution of the values of pulse wave velocity, diameter, intima-media thickness and relative distensibility of the carotid artery, in addition to assessing the demographic and clinical determinants of those parameters and their correlations. This study evaluated 210 individuals (54% women; mean age, 44 ± 13 years) with no evidence of cardiovascular disease. The carotid-femoral pulse wave velocity was measured with a Complior{sup ®} device. The functional and structural properties of the carotid artery were assessed by using radiofrequency ultrasound. The means of the following parameters were: pulse wave velocity, 8.7 ± 1.5 m/s; diameter, 6,707.9 ± 861.6 μm; intima-media thickness, 601 ± 131 μm; relative distensibility, 5.3 ± 2.1%. No significant difference related to sex or ethnicity was observed. On multiple linear logistic regression, the factors independently related to the vascular parameters were: pulse wave velocity, to age (p < 0.01) and triglycerides (p = 0.02); intima-media thickness, to age (p < 0.01); diameter, to creatinine (p = 0.03) and age (p = 0.02); relative distensibility, to age (p < 0.01) and systolic and diastolic blood pressures (p = 0.02 and p = 0.01, respectively). Pulse wave velocity showed a positive correlation with intima media thickness (p < 0.01) and with relative distensibility (p < 0.01), while diameter showed a positive correlation with distensibility (p = 0.03). In healthy individuals, age was the major factor related to aortic stiffness, while age and diastolic blood pressure related to the carotid functional measure

  11. Determinants of Functional and Structural Properties of Large Arteries in Healthy Individuals

    International Nuclear Information System (INIS)

    Tolezani, Elaine Cristina; Costa-Hong, Valéria; Correia, Gustavo; Mansur, Alfredo José; Drager, Luciano Ferreira; Bortolotto, Luiz Aparecido

    2014-01-01

    Changes in the properties of large arteries correlate with higher cardiovascular risk. Recent guidelines have included the assessment of those properties to detect subclinical disease. Establishing reference values for the assessment methods as well as determinants of the arterial parameters and their correlations in healthy individuals is important to stratify patients. To assess, in healthy adults, the distribution of the values of pulse wave velocity, diameter, intima-media thickness and relative distensibility of the carotid artery, in addition to assessing the demographic and clinical determinants of those parameters and their correlations. This study evaluated 210 individuals (54% women; mean age, 44 ± 13 years) with no evidence of cardiovascular disease. The carotid-femoral pulse wave velocity was measured with a Complior ® device. The functional and structural properties of the carotid artery were assessed by using radiofrequency ultrasound. The means of the following parameters were: pulse wave velocity, 8.7 ± 1.5 m/s; diameter, 6,707.9 ± 861.6 μm; intima-media thickness, 601 ± 131 μm; relative distensibility, 5.3 ± 2.1%. No significant difference related to sex or ethnicity was observed. On multiple linear logistic regression, the factors independently related to the vascular parameters were: pulse wave velocity, to age (p < 0.01) and triglycerides (p = 0.02); intima-media thickness, to age (p < 0.01); diameter, to creatinine (p = 0.03) and age (p = 0.02); relative distensibility, to age (p < 0.01) and systolic and diastolic blood pressures (p = 0.02 and p = 0.01, respectively). Pulse wave velocity showed a positive correlation with intima media thickness (p < 0.01) and with relative distensibility (p < 0.01), while diameter showed a positive correlation with distensibility (p = 0.03). In healthy individuals, age was the major factor related to aortic stiffness, while age and diastolic blood pressure related to the carotid functional measure. The

  12. Determinants of Functional and Structural Properties of Large Arteries in Healthy Individuals

    Directory of Open Access Journals (Sweden)

    Elaine Cristina Tolezani

    2014-11-01

    Full Text Available Background: Changes in the properties of large arteries correlate with higher cardiovascular risk. Recent guidelines have included the assessment of those properties to detect subclinical disease. Establishing reference values for the assessment methods as well as determinants of the arterial parameters and their correlations in healthy individuals is important to stratify patients. Objective: To assess, in healthy adults, the distribution of the values of pulse wave velocity, diameter, intima-media thickness and relative distensibility of the carotid artery, in addition to assessing the demographic and clinical determinants of those parameters and their correlations. Methods: This study evaluated 210 individuals (54% women; mean age, 44 ± 13 years with no evidence of cardiovascular disease. The carotid-femoral pulse wave velocity was measured with a Complior® device. The functional and structural properties of the carotid artery were assessed by using radiofrequency ultrasound. Results: The means of the following parameters were: pulse wave velocity, 8.7 ± 1.5 m/s; diameter, 6,707.9 ± 861.6 μm; intima-media thickness, 601 ± 131 μm; relative distensibility, 5.3 ± 2.1%. No significant difference related to sex or ethnicity was observed. On multiple linear logistic regression, the factors independently related to the vascular parameters were: pulse wave velocity, to age (p < 0.01 and triglycerides (p = 0.02; intima-media thickness, to age (p < 0.01; diameter, to creatinine (p = 0.03 and age (p = 0.02; relative distensibility, to age (p < 0.01 and systolic and diastolic blood pressures (p = 0.02 and p = 0.01, respectively. Pulse wave velocity showed a positive correlation with intima media thickness (p < 0.01 and with relative distensibility (p < 0.01, while diameter showed a positive correlation with distensibility (p = 0.03. Conclusion: In healthy individuals, age was the major factor related to aortic stiffness, while age and diastolic

  13. Refractory Hypertension: Determination of Prevalence, Risk Factors and Comorbidities in a Large, Population-Based Cohort

    Science.gov (United States)

    Calhoun, David A.; Booth, John N.; Oparil, Suzanne; Irvin, Marguerite R.; Shimbo, Daichi; Lackland, Daniel T.; Howard, George; Safford, Monika M.; Muntner, Paul

    2014-01-01

    Refractory hypertension is an extreme phenotype of antihypertensive treatment failure. Participants in the REasons for Geographic And Racial Differences in Stroke (REGARDS) Study, a large (n=30,239), population-based cohort were evaluated to determine the prevalence of refractory hypertension and associated cardiovascular risk factors and comorbidities. Refractory hypertension was defined as uncontrolled blood pressure (systolic/diastolic ≥ 140/90 mm Hg) on ≥ 5 antihypertensive drug classes. Participants with resistant hypertension (systolic/diastolic ≥140/90 mm Hg on ≥ 3 orhypertensive participants served as comparator groups. Of 14,809 REGARDS participants receiving antihypertensive treatment, 78 (0.5%) had refractory hypertension. The prevalence of refractory hypertension was 3.6% among participants with resistant hypertension(n=2,144) and 41.7% among participants on 5 or more antihypertensive drug classes. Among all hypertensive participants, African American race, male gender, living in the stroke belt or buckle, higher body mass index, lower heart rate, reduced estimated glomerular filtration rate, albuminuria, diabetes and history of stroke and coronary heart disease were associated with refractory hypertension. Compared to resistant hypertension, prevalence ratios for refractory hypertension were increased for African Americans (3.00, 95% CI 1.68 – 5.37) and those with albuminuria (2.22, 95% CI 1.40 – 3.52) and diabetes (2.09, 95% CI 1.32 – 3.31). The median 10-year Framingham risk for coronary heart disease and stroke was higher among participants with refractory hypertension compared to either comparator group. These data indicate that while resistant hypertension is relatively common among treated hypertensive patients, true antihypertensive treatment failure is rare. PMID:24324035

  14. Determinants of successful CD8+ T-cell adoptive immunotherapy for large established tumors in mice.

    Science.gov (United States)

    Klebanoff, Christopher A; Gattinoni, Luca; Palmer, Douglas C; Muranski, Pawel; Ji, Yun; Hinrichs, Christian S; Borman, Zachary A; Kerkar, Sid P; Scott, Christopher D; Finkelstein, Steven E; Rosenberg, Steven A; Restifo, Nicholas P

    2011-08-15

    Adoptive cell transfer (ACT) of tumor infiltrating or genetically engineered T cells can cause durable responses in patients with metastatic cancer. Multiple clinically modifiable parameters can comprise this therapy, including cell dose and phenotype, in vivo antigen restimulation, and common gamma-chain (γ(c)) cytokine support. However, the relative contributions of each these individual components to the magnitude of the antitumor response have yet to be quantified. To systematically and quantitatively appraise each of these variables, we employed the Pmel-1 mouse model treating large, established B16 melanoma tumors. In addition to cell dose and magnitude of in vivo antigen restimulation, we also evaluated the relative efficacy of central memory (T(CM)), effector memory (T(EM)), and stem cell memory (T(SCM)) subsets on the strength of tumor regression as well as the dose and type of clinically available γ(c) cytokines, including IL-2, IL-7, IL-15, and IL-21. We found that cell dose, T-cell differentiation status, and viral vaccine titer each were correlated strongly and significantly with the magnitude of tumor regression. Surprisingly, although the total number of IL-2 doses was correlated with tumor regression, no significant benefit to prolonged (≥6 doses) administration was observed. Moreover, the specific type and dose of γ(c) cytokine only moderately correlated with response. Collectively, these findings elucidate some of the key determinants of successful ACT immunotherapy for the treatment of cancer in mice and further show that γ(c) cytokines offer a similar ability to effectively drive antitumor T-cell function in vivo. ©2011 AACR.

  15. Application of k0-based internal monostandard NAA for large sample analysis of clay pottery. As a part of inter comparison exercise

    International Nuclear Information System (INIS)

    Acharya, R.; Dasari, K.B.; Pujari, P.K.; Swain, K.K.; Shinde, A.D.; Reddy, A.V.R.

    2014-01-01

    As a part of inter comparison exercise of an IAEA Coordinated Research Project on large sample neutron activation analysis, a large size and non standard geometry size pottery replica (obtained from Peru) was analyzed by k 0 -based internal monostandard neutron activation analysis (IM-NAA). Two large size sub samples (0.40 and 0.25 kg) were irradiated at graphite reflector position of AHWR Critical Facility in BARC, Trombay, Mumbai, India. Small samples (100-200 mg) were also analyzed by IM-NAA for comparison purpose. Radioactive assay was carried out using a 40 % relative efficiency HPGe detector. To examine homogeneity of the sample, counting was also carried out using X-Z rotary scanning unit. In situ relative detection efficiency was evaluated using gamma rays of the activation products in the irradiated sample in the energy range of 122-2,754 keV. Elemental concentration ratios with respect to Na of small size (100 mg mass) as well as large size (15 and 400 g) samples were used to check the homogeneity of the samples. Concentration ratios of 18 elements such as K, Sc, Cr, Mn, Fe, Co, Zn, As, Rb, Cs, La, Ce, Sm, Eu, Yb, Lu, Hf and Th with respect to Na (internal mono standard) were calculated using IM-NAA. Absolute concentrations were arrived at for both large and small samples using Na concentration, obtained from relative method of NAA. The percentage combined uncertainties at ±1 s confidence limit on the determined values were in the range of 3-9 %. Two IAEA reference materials SL-1 and SL-3 were analyzed by IM-NAA to evaluate accuracy of the method. (author)

  16. 76 FR 71354 - Certain Muzzle-Loading Firearms and Components Thereof Determination To Review in Part ALJ...

    Science.gov (United States)

    2011-11-17

    ... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-777] Certain Muzzle-Loading Firearms and Components Thereof Determination To Review in Part ALJ Initial Determination; Denial of Temporary Relief... importation, and the sale within the United States after importation of certain muzzle-loading firearms and...

  17. Complexometric determination: Part I - EDTA and complex formation with the Cu2+ ion

    Directory of Open Access Journals (Sweden)

    Rajković Miloš B.

    2002-01-01

    Full Text Available Compounds forming very stable complexes - chelates, have a wide field of application in analytical chemistry. The most famous group of these compounds are complexons. Complexons represent organic polyaminocarbonic acids as for example ethylenediaminetetraacetic acid (EDTA and its salts. The EDTA molecule has six coordinative sites. It is a hexadentate ligands i.e. it has two binding nitrogen atoms and four oxygen atoms from carboxyl groups and it forms complexes with almost all metal ions. EDTA as a tetraprotonic acid, H4Y disociates through four steps, yielding the ions HsY-, H2Y2-, HY3- and Y4-. Which of the EDTA forms will be encountered in a solution, depends on the pH. Due to the poor solubility of EDTA in pure water, as well as in most organic solvents, the disodium salt of EDTA Na2H2Y-2H2O, under the commercial name complexon III, is utilized for analytical determinations. In water, EDTA forms soluble, stabile chelate complexes with all cations, at the molar ratio 1:1, regardless of the charge of the metal ion. In contrast to other equilibria, which are mainly defined by Le Chatellier's principle, equilibria related to metal-EDTA complex formation are also dependent on the influence of the secondary equilibria of EDTA complex formation. Complexing reactions, which are equilibrium reactions, are simultaneously influenced by the following factors: solution pH and the presence of complexing agents which may also form a stabile complex with metal ions. The secondary reaction influence may be viewed and monitored through conditional stability constants. In the first part of the paper, the reaction of the formation of the Cu2+-ion complex with EDTA is analyzed beginning from the main reaction through various influences of secondary reactions on the complex Cu2+-EDTA: pH effect, complexation effect and hydrolysis effect. The equations are given for conditional stability constants, which include equilibrium reactions under actual conditions.

  18. What determines area burned in large landscapes? Insights from a decade of comparative landscape-fire modelling

    Science.gov (United States)

    Geoffrey J. Cary; Robert E. Keane; Mike D. Flannigan; Ian D. Davies; Russ A. Parsons

    2015-01-01

    Understanding what determines area burned in large landscapes is critical for informing wildland fire management in fire-prone environments and for representing fire activity in Dynamic Global Vegetation Models. For the past ten years, a group of landscape-fire modellers have been exploring the relative influence of key determinants of area burned in temperate and...

  19. The use of modal derivatives in determining stroke-dependent frequencies of large stroke flexure hinges

    NARCIS (Netherlands)

    van den Belt, Mieke; Schilder, Jurnan; Valasek, Michael; Sika, Zbynek; Vampola, Tomas

    2017-01-01

    Nowadays, a lot of use is made of large stroke flexure hinges in precision engineering. However, these large stroke flexure hinges typically lose stiffness in supporting direction during deflection. The lowest natural frequency is a commonly used measure for this property. Therefore, in shape and

  20. Determination of the in-containment source term for a Large-Break Loss of Coolant Accident

    International Nuclear Information System (INIS)

    2001-04-01

    This is the report of a project that focused on one of the most important design basis accidents: the Large Break Loss Of Coolant Accident (LBLOCA) (for pressurised water reactors). The first step in the calculation of the radiological consequences of this accident is the determination of the source term inside the containment. This work deals with this part of the calculation of the LBLOCA radiological consequences for which a previous benchmark (1988) has shown wide variations in the licensing practices adopted by European countries. The calculation of this source term may naturally be split in several steps (see chapter II), corresponding to several physical stages in the release of fission products: fraction of core failure, release from the damaged fuel, airborne part of the release and the release into the reactor coolant system and the sumps, chemical behaviour of iodine in the aqueous and gas phases, natural and spray removal in the containment atmosphere. A chapter is devoted to each of these topics. In addition, two other chapters deal with the basic assumptions to define the accidental sequence and the nuclides to be considered when computing doses associated with the LBLOCA. The report describes where there is agreement between the partner organisations and where there are still differences in approach. For example, there is agreement concerning the percentage of failed fuel which could be used in future licensing assessments (however this subject is still under discussion in France, a lower value is thinkable). For existing plants, AVN (Belgium) wishes to keep the initial licensing assumptions. For the release from damaged fuel, there is not complete agreement: AVN (Belgium) wishes to maintain its present approach. IPSN (France), GRS (Germany) and NNC (UK) prefer to use their own methodologies that result in slightly different values to the proposed values for a common position. There are presently no recommendations of the release of fuel particulates

  1. Matrix influences on the determination of common ions by using ion chromatography part 1--determination of inorganic anions.

    Science.gov (United States)

    Michalski, Rajmund; Lyko, Aleksandra; Kurzyca, Iwona

    2012-07-01

    Ion chromatography is the most popular instrumental analytical method used for the determination of anions and cations in water and wastewater. Isocratic ion chromatography with suppressed conductivity detection is frequently used in laboratories carrying out routine analyses of inorganic anions. The paper presents the results of the research into the influence of selected inorganic anions dominant in environmental samples (Cl(-), NO(3)(-), SO(4)(2-)) on the possibility of simultaneous determination of F(-), Cl(-), NO(2)(-), NO(3)(-), PO(4)(3-) and SO(4)(2-) with the application of this most popular ion chromatography type in standard separation conditions. Four Dionex and four Metrohm anion-exchange columns were tested in standard separation conditions recommended by their manufacturers with both standard solutions and environmental samples with complex matrix.

  2. Scramjet test flow reconstruction for a large-scale expansion tube, Part 1: quasi-one-dimensional modelling

    Science.gov (United States)

    Gildfind, D. E.; Jacobs, P. A.; Morgan, R. G.; Chan, W. Y. K.; Gollan, R. J.

    2017-11-01

    Large-scale free-piston driven expansion tubes have uniquely high total pressure capabilities which make them an important resource for development of access-to-space scramjet engine technology. However, many aspects of their operation are complex, and their test flows are fundamentally unsteady and difficult to measure. While computational fluid dynamics methods provide an important tool for quantifying these flows, these calculations become very expensive with increasing facility size and therefore have to be carefully constructed to ensure sufficient accuracy is achieved within feasible computational times. This study examines modelling strategies for a Mach 10 scramjet test condition developed for The University of Queensland's X3 facility. The present paper outlines the challenges associated with test flow reconstruction, describes the experimental set-up for the X3 experiments, and then details the development of an experimentally tuned quasi-one-dimensional CFD model of the full facility. The 1-D model, which accurately captures longitudinal wave processes, is used to calculate the transient flow history in the shock tube. This becomes the inflow to a higher-fidelity 2-D axisymmetric simulation of the downstream facility, detailed in the Part 2 companion paper, leading to a validated, fully defined nozzle exit test flow.

  3. Scramjet test flow reconstruction for a large-scale expansion tube, Part 1: quasi-one-dimensional modelling

    Science.gov (United States)

    Gildfind, D. E.; Jacobs, P. A.; Morgan, R. G.; Chan, W. Y. K.; Gollan, R. J.

    2018-07-01

    Large-scale free-piston driven expansion tubes have uniquely high total pressure capabilities which make them an important resource for development of access-to-space scramjet engine technology. However, many aspects of their operation are complex, and their test flows are fundamentally unsteady and difficult to measure. While computational fluid dynamics methods provide an important tool for quantifying these flows, these calculations become very expensive with increasing facility size and therefore have to be carefully constructed to ensure sufficient accuracy is achieved within feasible computational times. This study examines modelling strategies for a Mach 10 scramjet test condition developed for The University of Queensland's X3 facility. The present paper outlines the challenges associated with test flow reconstruction, describes the experimental set-up for the X3 experiments, and then details the development of an experimentally tuned quasi-one-dimensional CFD model of the full facility. The 1-D model, which accurately captures longitudinal wave processes, is used to calculate the transient flow history in the shock tube. This becomes the inflow to a higher-fidelity 2-D axisymmetric simulation of the downstream facility, detailed in the Part 2 companion paper, leading to a validated, fully defined nozzle exit test flow.

  4. Policy support for large scale demonstration projects for hydrogen use in transport. Deliverable D 5.1 (Part B)

    International Nuclear Information System (INIS)

    Ros, M.E.; Jeeninga, H.; Godfroij, P.

    2007-06-01

    This research addresses the possible policy support mechanisms for hydrogen use in transport to answer the question which policy support mechanism potentially is most effective to stimulate hydrogen in transport and especially for large scale demonstrations. This is done by investigating two approaches. First, the possible policy support mechanisms for energy innovations. Second, by relating these to the different technology development stages (R and D, early market and mass market stage) and reviewing their effect on different parts of the hydrogen energy chain (production, distribution and end-use). Additionally, a comparison of the currently policy support mechanisms used in Europe (on EU level) with the United States (National and State level) is made. The analysis shows that in principle various policy support mechanisms can be used to stimulate hydrogen. The choice for a policy support mechanism should depend on the need to reduce the investment cost (euros/MW), production/use cost (euros/GJ) or increase performance (euros/kg CO2 avoided) of a technology during its development. Careful thought has to be put into the design and choice of a policy support mechanism because it can have effects on other parts of the hydrogen energy chain, mostly how hydrogen is produced. The effectiveness of a policy support mechanism greatly depends on the ability to adapt to the developments of the technology and the changing requirements which come with technological progress. In time different policy support mechanisms have to be applied. For demonstration projects there is currently the tendency to apply R and D subsidies in Europe, while the United States applies a variety of policy support mechanisms. The United States not only has higher and more support for demonstration projects but also has stronger incentives to prepare early market demand (for instance requiring public procurement and sales obligations). In order to re-establish the level playing field, Europe may

  5. Determination of vertical velocities in the equatorial part of the western Indian Ocean

    Digital Repository Service at National Institute of Oceanography (India)

    Bahulayan, N.; Varadachari, V.V.R.

    Using steady state two-dimensional turbulent diffusion equations of salt and heat some important characteristics of vertical circulation in the equatorial part of the Indian Ocean have been evaluated and discussed. Upwelling and sinking velocities...

  6. A simple method for determining the activity of large-area beta sources constructed from anodized aluminum foils

    International Nuclear Information System (INIS)

    Stanga, D.

    2014-01-01

    A simple method has been developed for determining the activity of large-area beta reference sources in anodized aluminum foils. It is based on the modeling of the transmission of beta rays through thin foils in planar geometry using Monte Carlo simulation. The method was checked experimentally and measurement results show that the activity of large-area beta reference sources in anodized aluminum foils can be measured with standard uncertainties smaller than the limit of 10% required by ISO 8769. - Highlights: • A method for determining the activity of large-area beta sources is presented. • The method is based on a model of electron transport in planar geometry. • The method makes use of linear programming for determining the activity. • The uncertainty of the method is smaller than 10%

  7. The Role of the School Nurse in the Special Education Process: Part 2: Eligibility Determination and the Individualized Education Program.

    Science.gov (United States)

    Shannon, Robin Adair; Yonkaitis, Catherine Falusi

    2017-07-01

    This is the second of two articles outlining the professional school nurse's role in the special education process for students with disabilities. The Individuals with Disabilities in Education Improvement Act of 2004 mandates the special education process: identification, full and individual evaluation, eligibility determination, and development of the individual education program (IEP), including special education placement. Part 1 focused on the importance of the school nurse's role in student identification, response to intervention, and the full and individual evaluation. Part 2 highlights the school nurse's vital and unique contribution to the subsequent special education steps of eligibility determination, IEP development, and special education services placement and minutes.

  8. Sensitivity Analysis of Electromagnetic Induction Technique to Determine Soil Salinity in Large –Scale

    Directory of Open Access Journals (Sweden)

    Yousef Hasheminejhad

    2017-02-01

    Full Text Available Introduction: Monitoring and management of saline soils depends on exact and updatable measurements of soil electrical conductivity. Large scale direct measurements are not only expensive but also time consuming. Therefore application of near ground surface sensors could be considered as acceptable time- and cost-saving methods with high accuracy in soil salinity detection. . One of these relatively innovative methods is electromagnetic induction technique. Apparent soil electrical conductivity measurement by electromagnetic induction technique is affected by several key properties of soils including soil moisture and clay content. Materials and Methods: Soil salinity and apparent soil electrical conductivity data of two years of 50000 ha area in Sabzevar- Davarzan plain were used to evaluate the sensitivity of electromagnetic induction to soil moisture and clay content. Locations of the sampling points were determined by the Latin Hypercube Sampling strategy, based on 100 sampling points were selected for the first year and 25 sampling points for the second year. Regarding to difficulties in finding and sampling the points 97 sampling points were found in the area for the first year out of which 82 points were sampled down to 90 cm depth in 30 cm intervals and all of them were measured with electromagnetic induction device at horizontal orientation. The first year data were used for training the model which included 82 points measurement of bulk conductivity and laboratory determination of electrical conductivity of saturated extract, soil texture and moisture content in soil samples. On the other hand, the second year data which were used for testing the model integrated by 25 sampling points and 9 bulk conductivity measurements around each point. Electrical conductivity of saturated extract was just measured as the only parameter in the laboratory for the second year samples. Results and Discussion: Results of the first year showed a

  9. Moisture and nutrients determine the distribution and richness of India's large herbivore species assemblage

    NARCIS (Netherlands)

    Ahrestani, F.S.; Heitkonig, I.M.A.; Langevelde, van F.; Vaidyanathan, S.; Madhusudan, M.D.; Prins, H.H.T.

    2011-01-01

    The goal of this study was to test whether body-mass based foraging principles, guided by plant available moisture (PAM) and plant available nutrients (PAN), could explain large mammalian herbivore species distribution and richness in India. We tested (1) whether the occurrence of larger-bodied

  10. Absolute activity determinations on large volume geological samples independent of self-absorption effects

    International Nuclear Information System (INIS)

    Wilson, W.E.

    1980-01-01

    This paper describes a method for measuring the absolute activity of large volume samples by γ-spectroscopy independent of self-absorption effects using Ge detectors. The method yields accurate matrix independent results at the expense of replicative counting of the unknown sample. (orig./HP)

  11. 12 CFR 360.9 - Large-bank deposit insurance determination modernization.

    Science.gov (United States)

    2010-01-01

    ... market discipline, ensure equitable treatment of depositors at different institutions and reduce the FDIC... section for a covered institution that: Has a composite rating of 3, 4, or 5 under the Uniform Financial... operations of a large insured depository institution (defined as a “Covered Institution”) to continue...

  12. 40 CFR Appendix G to Part 75 - Determination of CO2 Emissions

    Science.gov (United States)

    2010-07-01

    ..., CO2 emissions from sorbent used in a wet flue gas desulfurization control system, fluidized bed boiler... Methods for Instrumental Determination of Carbon, Hydrogen, and Nitrogen in Petroleum Products and... Instrumental Determination of Carbon, Hydrogen, and Nitrogen in Laboratory Samples of Coal and Coke...

  13. 40 CFR Appendix Y to Part 51 - Guidelines for BART Determinations Under the Regional Haze Rule

    Science.gov (United States)

    2010-07-01

    ... Under the Regional Haze Rule Y Appendix Y to Part 51 Protection of Environment ENVIRONMENTAL PROTECTION... improve visibility in certain scenic areas of national importance. The scenic areas protected by section... Organizations, for adoption within each SIP or TIP. 2. The preamble to the 1999 regional haze rule discussed at...

  14. Determination of extent of the subsiding areas in the Czech part of Upper Silesian Basin

    Czech Academy of Sciences Publication Activity Database

    Kadlečík, Pavel; Kajzar, Vlastimil; Marek, Tomáš

    -, Part 2 (2012), s. 715-721 ISSN 1314-2704. [International Multidisciplinary Scientific GeoConference & EXPO SGEM 2012 /12./. Albena, 17.06.2012-23.06.2012] Institutional research plan: CEZ:AV0Z30460519; CEZ:AV0Z30860518 Keywords : Upper Silesian Basin * mining * subsidence Subject RIV: DE - Earth Magnetism, Geodesy, Geography

  15. A Simple Method to Estimate Large Fixed Effects Models Applied to Wage Determinants and Matching

    OpenAIRE

    Mittag, Nikolas

    2016-01-01

    Models with high dimensional sets of fixed effects are frequently used to examine, among others, linked employer-employee data, student outcomes and migration. Estimating these models is computationally difficult, so simplifying assumptions that are likely to cause bias are often invoked to make computation feasible and specification tests are rarely conducted. I present a simple method to estimate large two-way fixed effects (TWFE) and worker-firm match effect models without additional assum...

  16. Breakdown of hot-spot model in determining convective amplification in large homogeneous systems

    International Nuclear Information System (INIS)

    Mounaix, Philippe; Divol, Laurent

    2004-01-01

    Convective amplification in large homogeneous systems is studied, both analytically and numerically, in the case of a linear diffraction-free stochastic amplifier. Overall amplification does not result from successive amplifications in small scale high intensity hot spots, but from a single amplification in a delocalized mode of the driver field spreading over the whole interaction length. For this model, the hot-spot approach is found to systematically underestimate the gain factor by more than 50%

  17. Breaking symmetry in the structure determination of (large) symmetric protein dimers

    Energy Technology Data Exchange (ETDEWEB)

    Gaponenko, Vadim; Altieri, Amanda S.; Li, Jess; Byrd, R. Andrew [National Cancer Institute, Structural Biophysics Laboratory (United States)], E-mail: rabyrd@ncifcrf.gov

    2002-10-15

    We demonstrate a novel methodology to disrupt the symmetry in the NMR spectra of homodimers. A paramagnetic probe is introduced sub-stoichiometrically to create an asymmetric system with the paramagnetic probe residing on only one monomer within the dimer. This creates sufficient magnetic anisotropy for resolution of symmetry-related overlapped resonances and, consequently, detection of pseudocontact shifts and residual dipolar couplings specific to each monomeric component. These pseudocontact shifts can be readily incorporated into existing structure refinement calculations and enable determination of monomer orientation within the dimeric protein. This methodology can be widely used for solution structure determination of symmetric dimers.

  18. 33 CFR Appendix B to Part 155 - Determining and Evaluating Required Response Resources for Vessel Response Plans

    Science.gov (United States)

    2010-07-01

    ... Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) POLLUTION OIL OR HAZARDOUS MATERIAL POLLUTION PREVENTION REGULATIONS FOR VESSELS Pt. 155, App. B Appendix B to Part 155—Determining and... environment. For example, vessels moving from the ocean to a river port must identify appropriate equipment...

  19. 40 CFR Appendix C to Part 425 - Definition and Procedure for the Determination of the Method Detection Limit 1

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Definition and Procedure for the Determination of the Method Detection Limit 1 C Appendix C to Part 425 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS LEATHER TANNING AND FINISHING POINT SOURCE...

  20. A review of challenges to determining and demonstrating efficiency of large fire management

    Science.gov (United States)

    Matthew P. Thompson; Francisco Rodriguez y Silva; David E. Calkin; Michael S. Hand

    2017-01-01

    Characterising the impacts of wildland fire and fire suppression is critical information for fire management decision-making. Here, we focus on decisions related to the rare larger and longer-duration fire events, where the scope and scale of decision-making can be far broader than initial response efforts, and where determining and demonstrating efficiency of...

  1. Sensitive determination of iodide in the presence of large quantities of chloride

    International Nuclear Information System (INIS)

    Hainberger, L.; Lenzi, E.

    1982-01-01

    A determination of iodide with catalytic oxidation of p-phenetidine is described. A dye is formed with a maximum of absorption at 490 nm. The law of Lambert-Beer is obeyed between 0.6 and 2.2 ppm. Some of the interferents are examined. (Author)

  2. Compliance determination procedures for environmental radiation protection standards for uranium recovery facilities 40 CFR part 190

    International Nuclear Information System (INIS)

    1982-03-01

    Uranium Milling operations are licensed by the Nuclear Regulatory Commission and by some States in agreement with the Commission. The radiation dose to any individual from the operation of facilities within the uranium fuel cycle is limited to levels set by the Environmental Protection Agency. These levels are contained in the EPA Environmental Radiation Protection Standards for Nuclear Power Operations, in Part 190 of Title 40 of the Code of Federal Regulations (40 CFR Part 190). This report describes the procedures used within NRC's Uranium Recovery Licensing Branch for evaluating compliance with these regulations for uranium milling operations. The report contains descriptions of these procedures, dose factors for evaluating environmental measurement data, and guidance to the NRC staff reviewer

  3. Determinants of Police Strength in Large U.S. Cities during the 1990s: A Fixed-Effects Panel Analysis

    Science.gov (United States)

    McCarty, William P.; Ren, Ling; Zhao, Jihong

    2012-01-01

    The 1990s represented a unique decade in which to analyze the determinants of police strength in the United States. This decade was a time in which crime initially increased, then substantially decreased. Furthermore, this decade also was characterized by increases in the minority population throughout large American cities. Finally, the 1990s…

  4. Determination of supersymmetric parameters with neural networks at the large hadron collider

    International Nuclear Information System (INIS)

    Bornhauser, Nicki

    2013-12-01

    The LHC is running and in the near future potentially some signs of new physics are measured. In this thesis it is assumed that the underlying theory of such a signal would be identified and that it is some kind of minimal supersymmetric extension of the Standard Model. Generally, the mapping from the measurable observables onto the parameter values of the supersymmetric theory is unknown. Instead, only the opposite direction is known, i.e. for fixed parameters the measurable observables can be computed with some uncertainties. In this thesis, the ability of artifical neural networks to determine this unknown function is demonstrated. At the end of a training process, the created networks are capable to calculate the parameter values with errors for an existing measurement. To do so, at first a set of mostly counting observables is introduced. In the following, the usefulness of these observables for the determination of supersymmetric parameters is checked. This is done by applying them on 283 pairs of parameter sets of a MSSM with 15 parameters. These pairs were found to be indistinguishable at the LHC by another study, even without the consideration of SM background. It can be shown that 260 of these pairs can be discriminated using the introduced observables. Without systematic errors even all pairs can be distinguished. Also with the consideration of SM background still most pairs can be disentangled (282 without and 237 with systematic errors). This result indicates the usefulness of the observables for the direct parameter determination. The performance of neural networks is investigated for four different parameter regions of the CMSSM. With the right set of observables, the neural network approach generally could also be used for any other (non-supersymmetric) theory. In each region, a reference point with around 1,000 events after cuts should be determined in the context of a LHC with a center of mass energy of 14 TeV and an integrated luminosity of 10 fb

  5. Tumor and liver determinants of prognosis in unresectable hepatocellular carcinoma: a large case cohort study.

    Science.gov (United States)

    Carr, Brian I; Pancoska, Petr; Branch, Robert A

    2009-12-24

    967 patients with unresectable and untransplantable, biopsy-proven hepatocellular carcinoma (HCC) were prospectively evaluated at baseline and followed up till death. Survival was the end point. We found that male gender, ascites, cirrhosis, portal vein thrombosis (PVT), elevated AFP or bilirubin, or alkaline phosphatase, were each statistically significant adverse prognostic factors. Patients with normal AFP survived longer than those with elevated AFP, even in the presence of PVT, large or bilobar tumors or cirrhosis. We used a bivariate analysis to separate patient sub groups based on liver function and tumor characteristics and found clear discrimination in survival between subsets; in addition both cirrhosis and presence of PVT were significant factors. We also used a purely mathematical approach to derive subgroups and a prognostic model for individual patients. Interestingly, the two approaches gave similar predictive information, which opens the possibility of a more detailed mathematical analysis in the future. The results of this large dataset show that amongst non-surgical HCC patients, there are clear subsets with longer survival. The data supports the concept of heterogeneity of HCC. The three factors, bilirubin, AFP, and PVT predominate in prognosis.

  6. Determination of boron over a large dynamic range by prompt-gamma activation analysis

    International Nuclear Information System (INIS)

    Harrison, R.K.; Landsberger, S.

    2009-01-01

    An evaluation of the PGAA method for the determination of boron across a wide dynamic range of concentrations was performed for trace levels up to 5 wt.% boron. This range encompasses a transition from neutron transparency to significant self- shielding conditions. To account for self-shielding, several PGAA techniques were employed. First, a calibration curve was developed in which a set of boron standards was tested and the count rate to boron mass curve was determined. This set of boron measurements was compared with an internal standard self-shielding correction method and with a method for determining composition using PGAA peak ratios. The advantages and disadvantages of each method are analyzed. The boron concentrations of several laboratory-grade chemicals and standard reference materials were measured with each method and compared. The evaluation of the boron content of nanocrystalline transition metals prepared with a boron-containing reducing agent was also performed with each of the methods tested. Finally, the k 0 method was used for non-destructive measurement of boron in catalyst materials for the characterization of new non-platinum fuel cell catalysts.

  7. Simplified method for the determination of strontium-90 in large amounts of bone-ash

    International Nuclear Information System (INIS)

    Patti, F.; Jeanmaire, L.

    1966-06-01

    The principle of the determination is based on a 3-step process: 1) concentrating the strontium by attacking the ash with nitric acid; 2) elimination of residual phosphoric ions by a double precipitation of strontium oxalate; and 3) extraction of yttrium 90, counted in the oxalate form. The advantages of the method: -) using simple techniques it makes it possible to process 50 g of ash; -) the initial concentration of strontium considerably reduces the volume of the solutions as well as the size of precipitates handled. Fuming nitric acid is used in a specially designed burette. (authors) [fr

  8. 40 CFR 154.5 - Burden of persuasion in determinations under this part.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Burden of persuasion in determinations... (CONTINUED) PESTICIDE PROGRAMS SPECIAL REVIEW PROCEDURES General Provisions § 154.5 Burden of persuasion in... principle that the burden of persuasion that a pesticide product is entitled to registration or continued...

  9. Characterization of airborne particulate matter in Santiago, Chile. Part 6: elemental determination by neutron activation analysis

    International Nuclear Information System (INIS)

    Cassorla, V.; Rojas, X.; Andonie, O.; Gras, N.

    1995-01-01

    Instrumental neutron activation analysis was used for the chemical characterization of airborne particulate matter from some locations in the city of Santiago, Chile. The following elements were determined: Al, As, Br, Ca, Cl, Co, Cu, Cr, Fe, Mn, Na, Sb, Sc, V y Zn. The accuracy of the experimental procedure was evaluated using a standard reference material. (author). 3 refs, 3 figs, 4 tabs

  10. 32 CFR Appendix B to Part 223 - Guidelines for the Determination of DoD UCNI

    Science.gov (United States)

    2010-07-01

    ... information in another document or material is not, or is no longer, DoD UCNI; case-by-case determinations are... description of security system components intended to mitigate the consequences of an accident or act of... construction drawings of a DoD SNM facility showing construction characteristics of building and associated...

  11. Residual stress determination of direct metal laser sintered (DMLS) inconel specimens and parts

    Energy Technology Data Exchange (ETDEWEB)

    Watkins, Thomas R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Unocic, Kinga A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Maziasz, Philip J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Bunn, Jeffrey R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Fancher, Christopher M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Peralta, Alonso [Honeywell Aerospace, Phoenix, AZ (United States); Sundarraj, Suresh [Honeywell Aerospace, Phoenix, AZ (United States); Neumann, James [Honeywell Aerospace, Phoenix, AZ (United States)

    2018-01-01

    Residual stress determinations and microstructural studies were performed on a series of Inconel 718Plus prisms built using Direct Metal Laser Sintering (DMLS) at Honeywell Aerospace (hereafter also referred to as Honeywell). The results are being used to validate and improve existing models at Honeywell, and ultimately will expedite the implementation of DMLS throughout various industrial sectors (automotive, biomedical, etc.).

  12. Determination of telmisartan in human blood plasma: Part I: Immunoassay development

    NARCIS (Netherlands)

    Hempen, C.M.; Gläsle-Schwarz, Liane; Kunz, Ulrich; Karst, U.

    2006-01-01

    Telmisartan is an angiotensin II receptor antagonist and a known drug against high blood pressure. In this report, the development of a new and rapid analytical technique, an enzyme-linked immunosorbent assay (ELISA) for the determination of telmisartan in human blood plasma is described. The

  13. Determining an Estimate of an Equivalence Relation for Moderate and Large Sized Sets

    Directory of Open Access Journals (Sweden)

    Leszek Klukowski

    2017-01-01

    Full Text Available This paper presents two approaches to determining estimates of an equivalence relation on the basis of pairwise comparisons with random errors. Obtaining such an estimate requires the solution of a discrete programming problem which minimizes the sum of the differences between the form of the relation and the comparisons. The problem is NP hard and can be solved with the use of exact algorithms for sets of moderate size, i.e. about 50 elements. In the case of larger sets, i.e. at least 200 comparisons for each element, it is necessary to apply heuristic algorithms. The paper presents results (a statistical preprocessing, which enable us to determine the optimal or a near-optimal solution with acceptable computational cost. They include: the development of a statistical procedure producing comparisons with low probabilities of errors and a heuristic algorithm based on such comparisons. The proposed approach guarantees the applicability of such estimators for any size of set. (original abstract

  14. Method to Determine Appropriate Source Models of Large Earthquakes Including Tsunami Earthquakes for Tsunami Early Warning in Central America

    Science.gov (United States)

    Tanioka, Yuichiro; Miranda, Greyving Jose Arguello; Gusman, Aditya Riadi; Fujii, Yushiro

    2017-08-01

    Large earthquakes, such as the Mw 7.7 1992 Nicaragua earthquake, have occurred off the Pacific coasts of El Salvador and Nicaragua in Central America and have generated distractive tsunamis along these coasts. It is necessary to determine appropriate fault models before large tsunamis hit the coast. In this study, first, fault parameters were estimated from the W-phase inversion, and then an appropriate fault model was determined from the fault parameters and scaling relationships with a depth dependent rigidity. The method was tested for four large earthquakes, the 1992 Nicaragua tsunami earthquake (Mw7.7), the 2001 El Salvador earthquake (Mw7.7), the 2004 El Astillero earthquake (Mw7.0), and the 2012 El Salvador-Nicaragua earthquake (Mw7.3), which occurred off El Salvador and Nicaragua in Central America. The tsunami numerical simulations were carried out from the determined fault models. We found that the observed tsunami heights, run-up heights, and inundation areas were reasonably well explained by the computed ones. Therefore, our method for tsunami early warning purpose should work to estimate a fault model which reproduces tsunami heights near the coast of El Salvador and Nicaragua due to large earthquakes in the subduction zone.

  15. Possibilities of Spatial Data to Determine the Extent of the Occupancy of the Right-of-Way by Large-Format Advertisements

    Directory of Open Access Journals (Sweden)

    Bieda Agnieszka

    2017-06-01

    Full Text Available Large-format advertisements are becoming a more and more common element of building facades, especially in city centers. Placing an object of this type is not without significance to the real property management. A large-format advertising billboard on the facade, on the one hand, is associated with the possibility of renting advertising space, on the other - it can lead to the occupancy of a right-of-way, which results in a necessity to pay appropriate fees, in the amount regulated by the Act on Public Roads. Placing an object such as a large-format advertising billboard in a right-of-way requires a permit of the manager of this road. However, if a billboard is located on the facade of a building, occupancy of the right-of-way is not always the case. If the boundary of the road parcel runs along the contour of the building, a billboard placed on the elevation will always occupy the right-of-way. However, property boundaries often run at a distance from the building. Such situations - desired by managers - result in a noticeable increase in demand for surveying opinions to determine what part of the right-of-way is occupied by a large-format advertisement. This article analyzes the cases of the right-of-way being occupied by large-format advertising placed on the facades of buildings in the city center. For selected objects, information was obtained from public records, National Cartographic Documentation Center database, and direct surveying was performed with various techniques. This allowed for an objective assessment of the possible use of available surveying methods and the acquired spatial data to determine the right-of-way occupied by large-format advertisements for purposes of real estate management.

  16. Atomic structure of large angle grain boundaries determined by quantitative X-ray diffraction techniques

    International Nuclear Information System (INIS)

    Fitzsimmons, M.R.; Sass, S.L.

    1988-01-01

    Quantitative X-ray diffraction techniques have been used to determine the atomic structure of the Σ = 5 and 13 [001] twist boundaries in Au with a resolution of 0.09 Angstrom or better. The reciprocal lattices of these boundaries were mapped out using synchrotron radiation. The atomic structures were obtained by testing model structures against the intensity observations with a chi square analysis. The boundary structure were modeled using polyhedra, including octahedra, special configurations of tetrahedra and Archimedian anti-prisms, interwoven together by the boundary symmetry. The results of this work point to the possibility of obtaining general rules for grain boundary structure based on X-ray diffraction observations that give the atomic positions with high resolution

  17. Determination of soil liquefaction characteristics by large-scale laboratory tests

    International Nuclear Information System (INIS)

    1975-05-01

    The testing program described in this report was carried out to study the liquefaction behavior of a clean, uniform, medium sand. Horizontal beds of this sand, 42 inches by 90 inches by 4 inches were prepared by pluviation with a special sand spreader, saturated, and tested in a shaking table system designed for this program, which applied a horizontal cyclic shear stress to the specimens. Specimen size was selected to reduce boundary effects as much as possible. Values of pore pressures and shear strains developed during the tests are presented for sand specimens at relative densities of 54, 68, 82, and 90 percent, and the results interpreted to determine the values of the stress ratio causing liquefaction at the various relative densities

  18. A Large Cardiac Mass: Diagnosis of Caseous Mitral Annular Calcification and Determining Optimum Management Strategy

    Directory of Open Access Journals (Sweden)

    Emanuel A. Shapera

    2014-01-01

    Full Text Available A 64-year-old woman with dizziness and blurry vision underwent an evaluation for a possible stroke with a head-neck CT scan and a transthoracic echocardiogram. The head-neck CT scan was unremarkable, but the echocardiogram was notable for a 2.0×2.3 cm heterogeneous echodensity attached to the mitral valve. After a transesophageal echocardiogram and chest CT scan, the mass was determined to be a caseous mitral annular calcification, CMAC. This entity is a rare variant of MAC with an estimated prevalence of 0.068%. Echocardiographic techniques can distinguish CMAC from other intracardiac masses such as tumor, cyst, or abscess. CMAC is associated with cerebrovascular accidents; however, optimal treatment is controversial given the rarity of this clinical finding. Management strategies should be tailored based on the patient’s presentation, risk factors, and overall clinical circumstances.

  19. Determining tissue-lead levels in large game mammals harvested with lead bullets: human health concerns.

    Science.gov (United States)

    Tsuji, L J S; Wainman, B C; Jayasinghe, R K; VanSpronsen, E P; Liberda, E N

    2009-04-01

    Recently, the use of lead isotope ratios has definitively identified lead ammunition as a source of lead exposure for First Nations people, but the isotope ratios for lead pellets and bullets were indistinguishable. Thus, lead-contaminated meat from game harvested with lead bullets may also be contributing to the lead body burden; however, few studies have determined if lead bullet fragments are present in big game carcasses. We found elevated tissue-lead concentrations (up to 5,726.0 microg/g ww) in liver (5/9) and muscle (6/7) samples of big game harvested with lead bullets and radiographic evidence of lead fragments. Thus, we would advise that the tissue surrounding the wound channel be removed and discarded, as this tissue may be contaminated by lead bullet fragments.

  20. Large-scale determinants of intestinal schistosomiasis and intermediate host snail distribution across Africa

    DEFF Research Database (Denmark)

    Stensgaard, Anna-Sofie; Utzinger, Jürg; Vounatsou, Penelope

    2013-01-01

    The geographical ranges of most species, including many infectious disease agents and their vectors and intermediate hosts, are assumed to be constrained by climatic tolerances, mainly temperature. It has been suggested that global warming will cause an expansion of the areas potentially suitable...... impacts of climatic changes. Snail species distribution models included several combinations of climatic and habitat-related predictors; the latter divided into "natural" and "human-impacted" habitat variables to measure anthropogenic influence. The predictive performance of the combined snail...... are more likely to contract and/or move into cooler areas in the south and east. Importantly, we also note that even though climate per se matters, the impact of humans on habitat play a crucial role in determining the distribution of the intermediate host snails in Africa. Thus, a future contraction...

  1. DETERMINING THE LARGE-SCALE ENVIRONMENTAL DEPENDENCE OF GAS-PHASE METALLICITY IN DWARF GALAXIES

    International Nuclear Information System (INIS)

    Douglass, Kelly A.; Vogeley, Michael S.

    2017-01-01

    We study how the cosmic environment affects galaxy evolution in the universe by comparing the metallicities of dwarf galaxies in voids with dwarf galaxies in more dense regions. Ratios of the fluxes of emission lines, particularly those of the forbidden [O iii] and [S ii] transitions, provide estimates of a region’s electron temperature and number density. From these two quantities and the emission line fluxes [O ii] λ 3727, [O iii] λ 4363, and [O iii] λλ 4959, 5007, we estimate the abundance of oxygen with the direct T e  method. We estimate the metallicity of 42 blue, star-forming void dwarf galaxies and 89 blue, star-forming dwarf galaxies in more dense regions using spectroscopic observations from the Sloan Digital Sky Survey Data Release 7, as reprocessed in the MPA-JHU value-added catalog. We find very little difference between the two sets of galaxies, indicating little influence from the large-scale environment on their chemical evolution. Of particular interest are a number of extremely metal-poor dwarf galaxies that are less prevalent in voids than in the denser regions.

  2. Members of a large retroposon family are determinants of post-transcriptional gene expression in Leishmania.

    Directory of Open Access Journals (Sweden)

    Frédéric Bringaud

    2007-09-01

    Full Text Available Trypanosomatids are unicellular protists that include the human pathogens Leishmania spp. (leishmaniasis, Trypanosoma brucei (sleeping sickness, and Trypanosoma cruzi (Chagas disease. Analysis of their recently completed genomes confirmed the presence of non-long-terminal repeat retrotransposons, also called retroposons. Using the 79-bp signature sequence common to all trypanosomatid retroposons as bait, we identified in the Leishmania major genome two new large families of small elements--LmSIDER1 (785 copies and LmSIDER2 (1,073 copies--that fulfill all the characteristics of extinct trypanosomatid retroposons. LmSIDERs are approximately 70 times more abundant in L. major compared to T. brucei and are found almost exclusively within the 3'-untranslated regions (3'UTRs of L. major mRNAs. We provide experimental evidence that LmSIDER2 act as mRNA instability elements and that LmSIDER2-containing mRNAs are generally expressed at lower levels compared to the non-LmSIDER2 mRNAs. The considerable expansion of LmSIDERs within 3'UTRs in an organism lacking transcriptional control and their role in regulating mRNA stability indicate that Leishmania have probably recycled these short retroposons to globally modulate the expression of a number of genes. To our knowledge, this is the first example in eukaryotes of the domestication and expansion of a family of mobile elements that have evolved to fulfill a critical cellular function.

  3. Determination of nonmetallic elements in actinide complexes by oxygen flask combustion (OFC) (Part 2). Sulphur

    International Nuclear Information System (INIS)

    Ruikar, P.B.; Nagar, M.S.; Subramanian, M.S.

    1989-01-01

    This report describes the determination of sulphur in metallic complexes by oxygen flask combustion followed by conductivity titration with standard barium acetate solution in alcoholic medium and lead electrode titration using a lead ion sensitive electrode. Various organic ligands and uranyl and plutonyl synergistic complexes have been analysed by both these methods and the precision and accuracy of the results have been found to be satisfactory. (author). 12 refs., 12 tabs

  4. Determination of the real part of the η{sup '}-Nb optical potential

    Energy Technology Data Exchange (ETDEWEB)

    Nanova, Mariana [II. Physikalisches Institut, Justus-Liebig-Universitaet Giessen (Germany); Collaboration: CBELSA/TAPS-Collaboration

    2016-07-01

    The excitation function and momentum distribution of η{sup '} mesons have been measured in photo production off {sup 93}Nb in the energy range of 1.2-2.9 GeV. The experiment has been performed with the combined Crystal Barrel and MiniTAPS detector system, using tagged photon beams from the ELSA electron accelerator. Information on the sign and magnitude of the real part of the η{sup '}-Nb potential has been extracted from a comparison of the data with model calculations. An attractive potential of -(38 ± 9(stat) ± 12(syst)) MeV depth at normal nuclear matter density is deduced within model uncertainties. This value is consistent with the potential depth of -(37 ± 10(stat) ± 10(syst)) MeV obtained in an earlier measurement for a light nucleus (carbon).

  5. 40 CFR Appendix E to Part 61 - Compliance Procedures Methods for Determining Compliance With Subpart I

    Science.gov (United States)

    2010-07-01

    ... Part 61, Subpart I”. The compliance model is the highest level in the COMPLY computer code and provides... Ag-106 1.6E+00 1.6E+03 1.6E+06 Ag-106m 2.6E−03 2.6E+00 2.6E+03 Ag-108m 6.5E−06 6.5E−03 6.5E+00 Ag...−06 2.3E−03 2.3E+00 Am-242 1.8E−02 1.8E+01 1.8E+04 Am-242m 2.5E−06 2.5E−03 2.5E+00 Am-243 2.3E−06 2.3E...

  6. Determinants of corporate risk disclosure in large Spanish companies: a snapshot

    Directory of Open Access Journals (Sweden)

    Mónica Hernández Madrigal

    2015-01-01

    Full Text Available Las mejoras en la divulgación de información sobre riesgos constituyen una parte importante de las reformas sobre gobierno corporativo. El objetivo de este artículo es identificar los factores que explican el grado en el que 35 empresas espa ̃ nolas que cotizan en Bolsa divulgan información relacionada con los riesgos. El estudio considera la divulgación sobre riesgos que las empresas hacen por medio de los informes de gobierno corporativo del a ̃ no 2009. Utilizando la técnica del análisis de contenido, se desarrolló un índice con el fin de evaluar la cantidad y la calidad de la información sobre riesgos divulgada por las empresas espa ̃ nolas. Distintas características fueron seleccionadas y su influencia en el nivel de divulgación sobre riesgos fue probada empíricamente. Los resultados indican que el sector y el nivel de riesgo están positivamente relacionados con el grado de divulgación corporativa sobre riesgos. Este estudio contribuye a la investigación internacional sobre riesgos al extender el entendimiento sobre las prácticas de divulgación sobre riesgos y sus determinantes. Los resultados pueden ayudar a los reguladores y a los emisores de normas con el objeto de fomentar la divulgación sobre riesgos y mejorar la transparencia. Derechos Reservados © 2015 Universidad Nacional Autónoma de México, Facultad de Contaduría y Admin- istración. Este es un artículo de acceso abierto distribuido bajo los términos de la Licencia Creative Commons CC BY-NC-ND 4.0.

  7. Synthesis and Structure Determination of Large-Pore Zeolite SCM-14.

    Science.gov (United States)

    Luo, Yi; Smeets, Stef; Peng, Fei; Etman, Ahmed S; Wang, Zhendong; Sun, Junliang; Yang, Weimin

    2017-11-27

    SCM-14 (Sinopec Composite Material No. 14), a new stable germanosilicate zeolite with a 12×8×8-ring channel system, was synthesized using commercially available 4-pyrrolidinopyridine as organic structure-directing agents (OSDAs) in fluoride medium. The framework structure of SCM-14 was determined using rotation electron diffraction (RED), and refined against synchrotron X-ray powder diffraction (SXPD) data for both as-made and calcined materials. The framework structure of SCM-14 is closely related to that of three known zeolites: mordenite (MOR), GUS-1 (GON), and IM-16 (UOS). SCM-14 has the same projection as that of mordenite and GUS-1 when viewed along the 12-ring channels, and possesses two more straight 8-ring channels running perpendicular to the 12-ring channels. The structure of SCM-14 can be constructed by either the same layers as that of GUS-1 or the same columns as that of IM-16. Based on their structural relationship, three topologically reasonable hypothetical zeolites were predicted. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Determination of Process Parameters for High-Density, Ti-6Al-4V Parts Using Additive Manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Kamath, C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-08-10

    In our earlier work, we described an approach for determining the process parameters that re- sult in high-density parts manufactured using the additive-manufacturing process of selective laser melting (SLM). Our approach, which combines simple simulations and experiments, was demon- strated using 316L stainless steel. We have also used the approach successfully for several other materials. This short note summarizes the results of our work in determining process parameters for Ti-6Al-4V using a Concept Laser M2 system.

  9. A cephalometric study to determine the plane of occlusion in completely edentulous patients: part I.

    Science.gov (United States)

    Hindocha, Amit D; Vartak, Vikas N; Bhandari, Aruna J; Dudani, Mohit

    2010-12-01

    To determine the relationship between the plane of occlusion and the Camper's line (ala-tragus line). Lateral cephalograms of 105 dentulous subjects were obtained after outlining the tragus and the base of the ala of the nose with radiopaque markers. Tracings of the cephalograms were done and the relationship between the plane of occlusion and the Camper's line (ala-tragus line) was noted. The most common tragal reference as a posterior landmark for determination of plane of occlusion was found to be below inferior (in 30.48% of subjects), and inferior (in 24.76% of subjects). The least common tragal reference was found to be above superior (in 3.82% of subjects) followed by superior of tragus and the point between superior and middle of the tragus (in 6.66% of subjects). The tragal reference in this study population was more towards the inferior of the tragus, with most of the times being below the inferior border. Therefore, the orientation of the plane of occlusion using the superior of tragus as a posterior landmark (according to the widely accepted definition of Camper's line) may be considered to be questionable. Further, the use of the tragus as a posterior landmark for the orientation of the plane of occlusion may be questioned on the basis of the findings of this study.

  10. Full paleostress tensor reconstruction using quartz veins of Panasqueira Mine, central Portugal; part I: Paleopressure determination

    Science.gov (United States)

    Jaques, Luís; Pascal, Christophe

    2017-09-01

    Paleostress tensor restoration methods are traditionally limited to reconstructing geometrical parameters and are unable to resolve stress magnitudes. Based on previous studies we further developed a methodology to restore full paleostress tensors. We concentrated on inversion of Mode I fractures and acquired data in Panasqueira Mine, Portugal, where optimal exposures of mineralized quartz veins can be found. To carry out full paleostress restoration we needed to determine (1) pore (paleo)pressure and (2) vein attitudes. The present contribution focuses specifically on the determination of pore pressure. To these aims we conducted an extensive fluid inclusion study to derive fluid isochores from the quartz of the studied veins. To constrain P-T conditions, we combined these isochores with crystallisation temperatures derived from geochemical analyses of coeval arsenopyrite. We also applied the sphalerite geobarometer and considered two other independent pressure indicators. Our results point to pore pressures of ∼300 MPa and formation depths of ∼10 km. Such formation depths are in good agreement with the regional geological evolution. The obtained pore pressure will be merged with vein inversion results, in order to achieve full paleostress tensor restoration, in a forthcoming companion paper.

  11. Contact-free sheet resistance determination of large area graphene layers by an open dielectric loaded microwave cavity

    International Nuclear Information System (INIS)

    Shaforost, O.; Wang, K.; Adabi, M.; Guo, Z.; Hanham, S.; Klein, N.; Goniszewski, S.; Gallop, J.; Hao, L.

    2015-01-01

    A method for contact-free determination of the sheet resistance of large-area and arbitrary shaped wafers or sheets coated with graphene and other (semi) conducting ultrathin layers is described, which is based on an open dielectric loaded microwave cavity. The sample under test is exposed to the evanescent resonant field outside the cavity. A comparison with a closed cavity configuration revealed that radiation losses have no significant influence of the experimental results. Moreover, the microwave sheet resistance results show good agreement with the dc conductivity determined by four-probe van der Pauw measurements on a set of CVD samples transferred on quartz. As an example of a practical application, correlations between the sheet resistance and deposition conditions for CVD graphene transferred on quartz wafers are described. Our method has a high potential as measurement standard for contact-free sheet resistance measurement and mapping of large area graphene samples

  12. Providing for energy efficiency in homes and small buildings. Part III. Determining which practices are most effective and installing materials

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-06-01

    The training program is designed to educate students and individuals in the importance of conserving energy and to provide for developing skills needed in the application of energy-saving techniques that result in energy-efficient buildings. A teacher guide and student workbook are available to supplement the basic manual. Subjects covered in Part III are: determining which practices are most efficient and economical; installing energy-saving materials; and improving efficiency of equipment.

  13. Managing the Social Determinants of Health: Part I: Fundamental Knowledge for Professional Case Management.

    Science.gov (United States)

    Fink-Samnick, Ellen

    PRIMARY PRACTICE SETTING(S):: Applicable to health and behavioral health settings, wherever case management is practiced. The SDH pose major challenges to the health care workforce in terms of effective resource provision, health and behavioral health treatment planning plus adherence, and overall coordination of care. Obstacles and variances to needed interventions easily lead to less than optimal outcomes for case managers and their health care organizations. Possessing sound knowledge and clear understanding of each SDH, the historical perspectives, main theories, and integral dynamics, as well as creative resource solutions, all support a higher level of intentional and effective professional case management practice. Those persons and communities impacted most by the SDH comprise every case management practice setting. These clients can be among the most vulnerable and disenfranchised members of society, which can easily engender biases on the part of the interprofessional workforce. They are also among the costliest to care for with 50% of costs for only 5% of the population. Critical attention to knowledge about managing the SDH leverages and informs case management practice, evolves more effective programming, and enhances operational outcomes across practice settings.

  14. Determination of crystal structures with large known fragments directly from measured X-ray powder diffraction intensities

    International Nuclear Information System (INIS)

    Rius, J.; Miravitlles, C.

    1988-01-01

    A strategy for the determination of crystal structures with large known fragments directly from measured X-ray powder diffraction intensities is presented. It is based on the automated full-symmetry Patterson search method described by Rius and Miravitlles where the Fourier coefficients of the observed Patterson function are modified to allow the use of powder diffraction intensity data. Its application to two structures, one with simulated and one with experimental data, is shown. (orig.)

  15. Thickness determination of large-area films of yttria-stabilized zirconia produced by pulsed laser deposition

    Energy Technology Data Exchange (ETDEWEB)

    Pryds, N. [Materials Research Department, Riso National Laboratory, DK-4000 Roskilde (Denmark)]. E-mail: nini.pryds@risoe.dk; Toftmann, B. [Department of Optics and Plasma Research, Riso National Laboratory, DK-4000 Roskilde (Denmark); Bilde-Sorensen, J.B. [Materials Research Department, Riso National Laboratory, DK-4000 Roskilde (Denmark); Schou, J. [Department of Optics and Plasma Research, Riso National Laboratory, DK-4000 Roskilde (Denmark); Linderoth, S. [Materials Research Department, Riso National Laboratory, DK-4000 Roskilde (Denmark)

    2006-04-30

    Films of yttria-stabilized zirconia (YSZ) on a polished silicon substrate of diameter up to 125 mm have been produced in a large-area pulsed laser deposition (PLD) setup under typical PLD conditions. The film thickness over the full film area has been determined by energy-dispersive X-ray spectrometry in a scanning electron microscope (SEM) with use of a method similar to one described by Bishop and Poole. The attenuation of the electron-induced X-rays from the Si wafer by the film was monitored at a number of points along a diameter and the thickness was determined by Monte Carlo simulations of the attenuation for various values of film thickness with the program CASINO. These results have been compared with direct measurements in the SEM of the film thickness on a cross-section on one of the wafers. The results of these measurements demonstrate the ability of this technique to accurately determine the thickness of a large film, i.e. up to diameters of 125 mm, in a relatively short time, without destroying the substrate, without the need of a standard sample and without the need of a flat substrate. We have also demonstrated that by controlling the deposition parameters large-area YSZ films with uniform thickness can be produced.

  16. Thickness determination of large-area films of yttria-stabilized zirconia produced by pulsed laser deposition

    International Nuclear Information System (INIS)

    Pryds, N.; Toftmann, B.; Bilde-Sorensen, J.B.; Schou, J.; Linderoth, S.

    2006-01-01

    Films of yttria-stabilized zirconia (YSZ) on a polished silicon substrate of diameter up to 125 mm have been produced in a large-area pulsed laser deposition (PLD) setup under typical PLD conditions. The film thickness over the full film area has been determined by energy-dispersive X-ray spectrometry in a scanning electron microscope (SEM) with use of a method similar to one described by Bishop and Poole. The attenuation of the electron-induced X-rays from the Si wafer by the film was monitored at a number of points along a diameter and the thickness was determined by Monte Carlo simulations of the attenuation for various values of film thickness with the program CASINO. These results have been compared with direct measurements in the SEM of the film thickness on a cross-section on one of the wafers. The results of these measurements demonstrate the ability of this technique to accurately determine the thickness of a large film, i.e. up to diameters of 125 mm, in a relatively short time, without destroying the substrate, without the need of a standard sample and without the need of a flat substrate. We have also demonstrated that by controlling the deposition parameters large-area YSZ films with uniform thickness can be produced

  17. Is Income Inequality a Determinant of Population Health? Part 1. A Systematic Review

    Science.gov (United States)

    Lynch, John; Smith, George Davey; Harper, Sam; Hillemeier, Marianne; Ross, Nancy; Kaplan, George A; Wolfson, Michael

    2004-01-01

    This article reviews 98 aggregate and multilevel studies examining the associations between income inequality and health. Overall, there seems to be little support for the idea that income inequality is a major, generalizable determinant of population health differences within or between rich countries. Income inequality may, however, directly influence some health outcomes, such as homicide in some contexts. The strongest evidence for direct health effects is among states in the United States, but even that is somewhat mixed. Despite little support for a direct effect of income inequality on health per se, reducing income inequality by raising the incomes of the most disadvantaged will improve their health, help reduce health inequalities, and generally improve population health. PMID:15016244

  18. Part 1: determination of radioactive disequilibrium in uranium ores by alpha-spectrometry

    International Nuclear Information System (INIS)

    Killeen, P.G.; Carmichael, C.M.

    1976-01-01

    An α-spectrometric method of detecting the presence of disequilibrium in the 238 U decay series has been developed. A silicon semi-conductor detector and a 1024 channel pulse height analyzer were used to obtain alpha particle energy spectra of uraniferous rocks and minerals. 'Infinitely thick' sources were used to avoid the problems involved in preparation of 'infinitely thin' sources. The method involves the generation of theoretical energy distributions for infinitely thick sources. Complete theoretical spectra were computed for comparison with experimentally obtained alpha particle energy spectra of rocks and minerals. The presence and extent of disequilibrium in the 238 U decay series in a rock is determined from the residual spectrum obtained by subtracting a fitted theoretical spectrum from the measured spectrum of a rock. (author)

  19. Determination of element distributions between symplasm and apoplasm of cucumber plant parts

    International Nuclear Information System (INIS)

    Varga, A.; Zaray, G.; Fodor, F.

    2000-01-01

    Total reflection x-ray fluorescence analysis (TXRF) is a suitable method for determination of trace elements in biological samples due to its low detection limits, small sample demand, simple quantification and the absence of memory effects. In the present work the concentration of Pb, Cd, Ni, Mn and Fe was determined inside the cells (symplasm) and in the space among the cells (apoplasm) of cucumber plants. The cucumber seeds were grown in different nutrient solutions containing iron as Fe(III)-EDTA or Fe(III)-citrate, as well as Pb, Cd or Ni as contaminants in concentration of 10 -5 M. After growing period and the appropriate pretreatment (infiltration, leaching, washing and drying) the roots and the leaves were prepared for the analysis using a microwave assisted digestion system. The solutions obtained were spiked with Ni (in the case of the experiments with Pb) or Ga as internal standard. It was established that in the root the relative amount of lead in the symplasm related to the total absorbed amount (symplasm + apoplasm) is 2.5 % in presence of EDTA and 24% in presence of citrate. Studying its transport to the shoots, the amount of lead shows a decreasing tendency towards the young leaves and the symplasm/apoplasm ratio also changes: the ratio increased up to 66 % and 50 % in case of EDTA and citrate, respectively. Investigating of iron content similar phenomenon could be observed, however the presence of lead and complex forming agents did not result in any significant changes of the manganese distribution between symplasm and apoplasm. The results of experiments with Ni and Cd contaminants will be presented and discussed in the lecture. (author)

  20. A General Case to Determine Dimensions and Their Tolerance Zones for the Thread Parts of Epicyclic Roller-Screw Mechanisms

    Directory of Open Access Journals (Sweden)

    D. S. Blinov

    2017-01-01

    Full Text Available The most important trend in the development of aerospace industry is to increase load capacity of mechanisms, assemblies, and parts without increasing their size and weight. The above is also true for widely used in aircrafts and the most promising up to date Epicyclic Roller-Screw Mechanisms (ERSM that convert rotational movement into translational one. Previously (in the article, it was proposed to increase the load capacity (approximately by 15% through reduction of included angle of ERSM threaded parts from 90° to 70°.However, such improvement of ERSM will change dimensions of the mechanism parts and its parameters and characteristics (efficiency factor, position of initial point of contact of the conjugated thread turns and parameters of their contact interaction, as well as kinematic parameters, which will require additional studies. If we take into account the priority of these studies, then surely we must begin with development of technique to determine dimensions of the ERSM main parts and their tolerance zones because we need drawings to manufacture and test the upgraded ERSM. We have developed a technique to calculate dimensions of the main parts of ERSM and associated tolerance zones that takes in to account the change of included angle of threaded parts of the mechanism and radius of circular arc according to which roller thread profile has been fulfilled. So the proposed technique is the general one in comparison with the previous ones.This technique uses various conditions and equations to determine dimensions of parts and associated tolerance zones. For example, a nut encircles a screw with rollers, and their dimensions form a closed dimension chain, in which the dimensions and associated tolerances must be such as to ensure ERSM assembling, on the one hand, and, on the other hand the backlash of the mechanism should be minimal to ensure high load capacity, kinematic accuracy, and rigidity of ERSM. We used the following

  1. What the recommended practice for setpoint determination methodologies does or does not do. Part 2

    International Nuclear Information System (INIS)

    Beuchel, B.E.; Annon, M.C.

    1991-01-01

    The long-awaited Recommended Practice (RP) to complement ISA S67.04-1987 Setpoints for Nuclear Safety-Related Instrumentation is very close to publication. The RP, entitled Methodologies for the Determination of Setpoints for Nuclear Safety-Related Instrumentation, has been prepared through the efforts of over 50 persons representing over 20 utilities, all four LWR NSSS vendors, three instrument manufacturers, several architectural engineering firms, numerous consulting firms and other individuals. Throughout the period during which the RP was being prepared, it became apparent to the RP Committee members that the scope and approaches outlined in the RP were not fully understood by the general nuclear community. Therefore, the goals of this paper are to enhance the understanding of the RP and facilitate the utilization of the RP by potential users. The primary objective of the paper is to provide a broad overview of the purpose and scope of the RP. This will be achieved by describing the general organization of the RP as well as a brief explanation of the contents of each section. The paper will also discuss the role of the RP in the development of actual setpoint calculations, i.e., and explanation of the need for a user's specific methodology document to customize the RP for a specific user. In addition, the paper identifies, and attempts to clarify, several potential misconceptions by users, as to what the RP does not do

  2. A method for simultaneous determination of wear-resistance of structurally identical machine parts with mutual friction

    International Nuclear Information System (INIS)

    Valigura, V.; Volyn'ski, A.

    1979-01-01

    There are mechanisms in the technique, boundary state of separate parts of which is determined by the process of wear of three elements of the mechanism, made of the same material (for example antifriction bearings). The main concept of wear determination in the case of such a mechanism is to conduct measurements by means of simultaneous application of three different methods, for example: the method of roentgen-fluorescence; the tracer technique with application of activation by means of irradiation by different elementary particles, practically by means of neutrons and protons; the method of artifical bases application. In the paper the method is presented having been developed in the Institute of Working Machines of the Poznan Polytechnic. This method of simultaneous investigation in the wear process of bearing rings, inner and outer, and rolling elements of roller bearings. All these elements of bearings are made of LX-15 steel. The method developed, permits to determine the wear sufficient for practical purposes sensitivity [ru

  3. Large-scale demonstration of disposal of decontaminated salt as saltstone. Part I. Construction, loading, and capping of lysimeters

    International Nuclear Information System (INIS)

    Wolf, H.C.

    1984-06-01

    The installation phase of a large-scale demonstration of the disposal concept for decontaminated, low-level radioactive salt waste at the Savannah River Plant was completed in December 1983 and January 1984. The installation entailed immobilizing 7500 gallons of decontaminated salt solution with a blended cement formulation and pouring the resulting grout, saltstone, into three specially designed lysimeters for extended in-field leaching tests under natural conditions. 4 references, 35 figures, 4 tables

  4. Study of energy determination of gamma-ray observed with an emulsion chamber with a large gap

    International Nuclear Information System (INIS)

    Inui, Tamiki; Otsuka, Taeko; Masaoka, Akiko

    1982-01-01

    The development of large size emulsion chambers has been made to study very high energy events. For this purpose, the chambers with exchangeable light sensitive layers are considered. The chambers have large gap for the exchange. In this case, it becomes hard to determine the energy of cascade shower. In this report, the authors describe on the experimental examples observed at Mt. Chacaltaya. The effect of a gap was investigated by these examples, and the simulation method by Okamoto and Shibata was applied to the chamber. The chamber used for the observation consisted of the top chamber of 11 c.u. and the bottom chamber of 15 c.u. There was a large gap of 170 cm between two chambers. Twelve showers in three families observed by this system were analyzed. The difference between the blackness in the top and bottom films was studied quantitatively. The blackness was calibrated for the electron density. Four methods of energy determination were studied. Among them, a method to employ the sum of the maximum blackness of a top film and that of a bottom one was used for the analysis. This method seemed to be more reliable than the old method. It was found by a simulation calculation that the recovery of shower in the bottom chamber was seen not only by hardrons but also by gamma-ray. (Kato, T.)

  5. Decreasing the roughage:concentrate ratio of a diet to determine the critical roughage part for beef cattle.

    Science.gov (United States)

    De Campeneere, S; Fiems, L O; De Boever, J L; Vanacker, J M; De Brabander, D L

    2002-02-01

    The critical roughage part (CRP) of 2 diet types was determined in a cross-over design with 6 double-muscled and 6 normally conformed Belgian Blue bulls fitted with rumen cannulae. The roughage:concentrate ratio was lowered weekly until signs of a lack of physical structure were observed. For diet 1, consisting of maize silage and concentrates, the initial proportion of maize silage was 25% of DM but it decreased weekly with 5% units of DM. For the second diet, consisting of wheat straw and concentrate, 12% straw (DM basis) was provided during the first week and thereafter the proportion of straw decreased weekly with 3% units of DM. Several directly observable parameters (rumen pH, feed intake, bloat, faecal consistency) were evaluated weekly for each bull. Apart from these direct indicators of acidosis, also other parameters, whose results were only available after the end of the trial, were determined (volatile fatty acid profile, lactic acid concentration, chewing time). The roughage part between the part fed when signs of a lack of physical structure was first observed and the part that was fed the week before, was considered as the CRP. Most animals showed no acute signs of clinical acidosis (directly observable parameters) and finished the trial on a 100% concentrate diet. However, in sacco rumen DM-degradabilities of maize silage, grass silage and wheat grain was depressed considerably when low roughage diets were fed. Based on all observed parameters, the mean CRP was calculated to be 14.7% for diet 1 and 8.1% for diet 2. The beef type (double-muscled or not) had no influence on the CRP.

  6. LOW PRESSURE CARBURIZING IN A LARGE-CHAMBER DEVICE FOR HIGH-PERFORMANCE AND PRECISION THERMAL TREATMENT OF PARTS OF MECHANICAL GEAR

    Directory of Open Access Journals (Sweden)

    Emilia Wołowiec-Korecka

    2017-03-01

    Full Text Available This paper presents the findings of research of a short-pulse low pressure carburizing technology developed for a new large-chamber furnace for high-performance and precision thermal treatment of parts of mechanical gear. Sections of the article discuss the novel constructions of the device in which parts being carburized flow in a stream, as well as the low-pressure carburizing experiment. The method has been found to yield uniform, even and repeatable carburized layers on typical gear used in automotive industry.

  7. CT imaging in a large part of the world: what we know and what we can learn

    International Nuclear Information System (INIS)

    Rehani, Madan M.

    2014-01-01

    This paper describes how cooperation among international organizations, as modeled in Europe, can work to improve imaging safety and standards for children throughout the world. This is demonstrated in the mechanisms employed in a large-scale multi-national study on CT imaging safety practices described elsewhere in this issue of Pediatric Radiology. Here we learn approaches through which CT safety standards have been achieved and the international resources available to help in standardizing safety practices in medical imaging. There are unique strengths of the approach in Europe, which has mandatory requirements on member states to facilitate strengthening of radiation protection. Most countries have national regulatory mechanisms for radiation protection in medicine. International organizations play a significant role in supporting projects in lower-resource countries such that a large proportion of radiologic professionals in low-resource countries are trained through assistance by these organizations. Many of these international organizations make it possible for professionals worldwide to download free training material. Collaboration among international organizations and the Image Gently campaign toward consensus with regard to radiation protection can go further than individual opinions in promoting a higher standard of radiation protection around the world. (orig.)

  8. Large-scale production of diesel-like biofuels - process design as an inherent part of microorganism development.

    Science.gov (United States)

    Cuellar, Maria C; Heijnen, Joseph J; van der Wielen, Luuk A M

    2013-06-01

    Industrial biotechnology is playing an important role in the transition to a bio-based economy. Currently, however, industrial implementation is still modest, despite the advances made in microorganism development. Given that the fuels and commodity chemicals sectors are characterized by tight economic margins, we propose to address overall process design and efficiency at the start of bioprocess development. While current microorganism development is targeted at product formation and product yield, addressing process design at the start of bioprocess development means that microorganism selection can also be extended to other critical targets for process technology and process scale implementation, such as enhancing cell separation or increasing cell robustness at operating conditions that favor the overall process. In this paper we follow this approach for the microbial production of diesel-like biofuels. We review current microbial routes with both oleaginous and engineered microorganisms. For the routes leading to extracellular production, we identify the process conditions for large scale operation. The process conditions identified are finally translated to microorganism development targets. We show that microorganism development should be directed at anaerobic production, increasing robustness at extreme process conditions and tailoring cell surface properties. All the same time, novel process configurations integrating fermentation and product recovery, cell reuse and low-cost technologies for product separation are mandatory. This review provides a state-of-the-art summary of the latest challenges in large-scale production of diesel-like biofuels. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  9. CT imaging in a large part of the world: what we know and what we can learn

    Energy Technology Data Exchange (ETDEWEB)

    Rehani, Madan M. [Massachusetts General Hospital and Harvard Medical School, Boston, MA (United States)

    2014-10-15

    This paper describes how cooperation among international organizations, as modeled in Europe, can work to improve imaging safety and standards for children throughout the world. This is demonstrated in the mechanisms employed in a large-scale multi-national study on CT imaging safety practices described elsewhere in this issue of Pediatric Radiology. Here we learn approaches through which CT safety standards have been achieved and the international resources available to help in standardizing safety practices in medical imaging. There are unique strengths of the approach in Europe, which has mandatory requirements on member states to facilitate strengthening of radiation protection. Most countries have national regulatory mechanisms for radiation protection in medicine. International organizations play a significant role in supporting projects in lower-resource countries such that a large proportion of radiologic professionals in low-resource countries are trained through assistance by these organizations. Many of these international organizations make it possible for professionals worldwide to download free training material. Collaboration among international organizations and the Image Gently campaign toward consensus with regard to radiation protection can go further than individual opinions in promoting a higher standard of radiation protection around the world. (orig.)

  10. A comparison of three design tree based search algorithms for the detection of engineering parts constructed with CATIA V5 in large databases

    Directory of Open Access Journals (Sweden)

    Robin Roj

    2014-07-01

    Full Text Available This paper presents three different search engines for the detection of CAD-parts in large databases. The analysis of the contained information is performed by the export of the data that is stored in the structure trees of the CAD-models. A preparation program generates one XML-file for every model, which in addition to including the data of the structure tree, also owns certain physical properties of each part. The first search engine is specializes in the discovery of standard parts, like screws or washers. The second program uses certain user input as search parameters, and therefore has the ability to perform personalized queries. The third one compares one given reference part with all parts in the database, and locates files that are identical, or similar to, the reference part. All approaches run automatically, and have the analysis of the structure tree in common. Files constructed with CATIA V5, and search engines written with Python have been used for the implementation. The paper also includes a short comparison of the advantages and disadvantages of each program, as well as a performance test.

  11. Nuclear fuel technology - Tank calibration and volume determination for nuclear materials accountancy - Part 2: Data standardization for tank calibration

    International Nuclear Information System (INIS)

    2007-01-01

    Measurements of the volume and height of liquid in a process accountancy tank are often made in order to estimate or verify the tank's calibration or volume measurement equation. The calibration equation relates the response of the tank's measurement system to some independent measure of tank volume. The ultimate purpose of the calibration exercise is to estimate the tank's volume measurement equation (the inverse of the calibration equation), which relates tank volume to measurement system response. In this part of ISO 18213, it is assumed that the primary measurement-system response variable is liquid height and that the primary measure of liquid content is volume. This part of ISO 18213 presents procedures for standardizing a set of calibration data to a fixed set of reference conditions so as to minimize the effect of variations in ambient conditions that occur during the measurement process. The procedures presented herein apply generally to measurements of liquid height and volume obtained for the purpose of calibrating a tank (i.e. calibrating a tank's measurement system). When used in connection with other parts of ISO 18213, these procedures apply specifically to tanks equipped with bubbler probe systems for measuring liquid content. The standardization algorithms presented herein can be profitably applied when only estimates of ambient conditions, such as temperature, are available. However, the most reliable results are obtained when relevant ambient conditions are measured for each measurement of volume and liquid height in a set of calibration data. Information is provided on scope, physical principles, data required, calibration data, dimensional changes in the tank, multiple calibration runs and results on standardized calibration data. Four annexes inform about density of water, buoyancy corrections for mass determination, determination of tank heel volume and statistical method for aligning data from several calibration runs. A bibliography is

  12. Large Eddy Simulation of Vertical Axis Wind Turbine wakes; Part I: from the airfoil performance to the very far wake

    Science.gov (United States)

    Chatelain, Philippe; Duponcheel, Matthieu; Caprace, Denis-Gabriel; Marichal, Yves; Winckelmans, Gregoire

    2017-11-01

    A vortex particle-mesh (VPM) method with immersed lifting lines has been developed and validated. Based on the vorticity-velocity formulation of the Navier-Stokes equations, it combines the advantages of a particle method and of a mesh-based approach. The immersed lifting lines handle the creation of vorticity from the blade elements and its early development. Large-eddy simulation (LES) of vertical axis wind turbine (VAWT) flows is performed. The complex wake development is captured in detail and over up to 15 diameters downstream: from the blades to the near-wake coherent vortices and then through the transitional ones to the fully developed turbulent far wake (beyond 10 rotor diameters). The statistics and topology of the mean flow are studied with respect to the VAWT geometry and its operating point. The computational sizes also allow insights into the detailed unsteady vortex dynamics and topological flow features, such as a recirculation region influenced by the tip speed ratio and the rotor geometry.

  13. Large-scale bioenergy production from soybeans and switchgrass in Argentina: Part A: Potential and economic feasibility for national and international markets

    NARCIS (Netherlands)

    van Dam, J.; Faaij, A.P.C.; Hilbert, J.; Petruzzi, H.; Turkenburg, W.C.

    2009-01-01

    This study focuses on the economic feasibility for large-scale biomass production from soybeans or switchgrass from a region in Argentina. This is determined, firstly, by estimating whether the potential supply of biomass, when food and feed demand are met, is sufficient under different scenarios to

  14. Modeling of biomass smoke injection into the lower stratosphere by a large forest fire (Part I: reference simulation

    Directory of Open Access Journals (Sweden)

    J. Trentmann

    2006-01-01

    Full Text Available Wildland fires in boreal regions have the potential to initiate deep convection, so-called pyro-convection, due to their release of sensible heat. Under favorable atmospheric conditions, large fires can result in pyro-convection that transports the emissions into the upper troposphere and the lower stratosphere. Here, we present three-dimensional model simulations of the injection of fire emissions into the lower stratosphere by pyro-convection. These model simulations are constrained and evaluated with observations obtained from the Chisholm fire in Alberta, Canada, in 2001. The active tracer high resolution atmospheric model (ATHAM is initialized with observations obtained by radiosonde. Information on the fire forcing is obtained from ground-based observations of the mass and moisture of the burned fuel. Based on radar observations, the pyro-convection reached an altitude of about 13 km, well above the tropopause, which was located at about 11.2 km. The model simulation yields a similarly strong convection with an overshoot of the convection above the tropopause. The main outflow from the pyro-convection occurs at about 10.6 km, but a significant fraction (about 8% of the emitted mass of the smoke aerosol is transported above the tropopause. In contrast to regular convection, the region with maximum updraft velocity in the pyro-convection is located close to the surface above the fire. This results in high updraft velocities >10 m s−1 at cloud base. The temperature anomaly in the plume decreases rapidly with height from values above 50 K at the fire to about 5 K at about 3000 m above the fire. While the sensible heat released from the fire is responsible for the initiation of convection in the model, the release of latent heat from condensation and freezing dominates the overall energy budget. Emissions of water vapor from the fire do not significantly contribute to the energy budget of the convection.

  15. Large-Scale Water Resources Management within the Framework of GLOWA-Danube - Part A: The Groundwater Model

    Science.gov (United States)

    Barthel, R.; Rojanschi, V.; Wolf, J.; Braun, J.

    2003-04-01

    the catchment developed by the research group uses a finite difference approach (MODFLOW). A transport model (nitrogen) will be added in a second stage (MT3D). A three-dimensional conceptual hydrogeological model consisting of four layers was developed. Only aquifers with basin-wide occurrence are considered. Aquifers on the local scale cannot be included in the model due to insufficient data availability, the model grid resolution (1km2) used and various limitations arising from the MODFLOW-approach. The cell size of 1 km is compulsory for all models in DANUBIA in order to facilitate 1:1 parameter exchange. The concept of DANUBIA is based on the parallel execution of strictly independent disciplinary models. At each time step, the required parameters are exchanged. On the "physical side" the groundwater model has interfaces to a soil water and a surface water model which provide important parameters that are used as model boundary conditions. The soil water model calculates the groundwater recharge as the infiltration through a layered soil zone. The surface water model calculates the heads in the rivers, which are used to determine flow from the aquifers to the rivers and vice versa. The main aim of the groundwater model is to assess and forecast quantity and quality of the groundwater resources together with the other physically based models under conditions of global change. On the "socio-economic side", the groundwater model exchanges data with the so-called "Actors" component, a group of models concerned with the human impact on the water cycle. The amount of groundwater extraction for drinking water purposes is a boundary condition of the groundwater model calculated by the Actors models. The feedback between demand and supply invokes the need for complex optimization algorithms.

  16. Determination of average fission fraction produced by 14 MeV neutrons in assemblies with large volume of depleted uranium

    International Nuclear Information System (INIS)

    Wang Dalun; Li Benci; Wang Xiuchun; Li Yijun; Zhang Shaohua; He Yongwu

    1991-07-01

    The average fission fraction of 238 U caused by 14 MeV neutrons in assemblies with large volume depleted uranium has been determined. The measured value of p f 238U (R ∞ depleted ) 14 was 0.897 ± 0.036. Measurements were also completed for neutron flux distribution and average fission fraction of 235 U isotope in depleted uranium sphere. Values of p f 238U (R depleted ) have been obtained by using a series of uranium spheres. For a sphere with Φ 600 the p f 23 '8 U (R 300 depleted ) is 0.823 ± 0.041, the density of depleted uranium assembly is 18.8g/cm 3 and total weight of assembly is about 2.8t

  17. Determination and Verification of the main Dynamic Characteristics of a Spatially Large Structure Using the Basic Records Combination Method

    Directory of Open Access Journals (Sweden)

    Patricia Murzea

    2013-09-01

    Full Text Available The aim of the paper is to present some methodological aspects regarding the determination of the vibration eigenmodes of a spatially large, symmetric structure and afterwards to show the obtained results for a spectral analysis of the ground motion in the horizontal plane, corresponding to steady state micro-tremors. The recorded velocigrams concern the rigid body motion of the main ring of the structure (translation along different horizontal directions and rotation with respect to the vertical symmetry axis as well as ovalization oscillations (mainly second order ovalization. The necessary data for the analysis was obtained through an efficient technique of combining basic records gathered with the help of data acquisition systems, on site, using three different schemes for the placement of the recording sensors.

  18. Determination of the State of Strain of Large Floating Covers Using Unmanned Aerial Vehicle (UAV) Aided Photogrammetry

    Science.gov (United States)

    Ong, Wern Hann; Chiu, Wing Kong; Kuen, Thomas; Kodikara, Jayantha

    2017-01-01

    Floating covers used in waste water treatment plants are one of the many structures formed with membrane materials. These structures are usually large and can spread over an area measuring 470 m × 170 m. The aim of this paper is to describe recent work to develop an innovative and effective approach for structural health monitoring (SHM) of such large membrane-like infrastructure. This paper will propose a potentially cost-effective non-contact approach for full-field strain and stress mapping using an unmanned aerial vehicle (UAV) mounted with a digital camera and a global positioning system (GPS) tracker. The aim is to use the images acquired by the UAV to define the geometry of the floating cover using photogrammetry. In this manner, any changes in the geometry of the floating cover due to forces acting beneath resulting from its deployment and usage can be determined. The time-scale for these changes is in terms of weeks and months. The change in the geometry can be implemented as input conditions to a finite element model (FEM) for stress prediction. This will facilitate the determination of the state of distress of the floating cover. This paper investigates the possibility of using data recorded from a UAV to predict the strain level and assess the health of such structures. An investigation was first conducted on a laboratory sized membrane structure instrumented with strain gauges for comparison against strains, which were computed from 3D scans of the membrane geometry. Upon validating the technique in the laboratory, it was applied to a more realistic scenario: an outdoor test membrane structure and capable UAV were constructed to see if the shape of the membrane could be computed. The membrane displacements were then used to calculate the membrane stress and strain, state demonstrating a new way to perform structural health monitoring on membrane structures. PMID:28788081

  19. Determination of the State of Strain of Large Floating Covers Using Unmanned Aerial Vehicle (UAV) Aided Photogrammetry.

    Science.gov (United States)

    Ong, Wern Hann; Chiu, Wing Kong; Kuen, Thomas; Kodikara, Jayantha

    2017-07-28

    Floating covers used in waste water treatment plants are one of the many structures formed with membrane materials. These structures are usually large and can spread over an area measuring 470 m × 170 m. The aim of this paper is to describe recent work to develop an innovative and effective approach for structural health monitoring (SHM) of such large membrane-like infrastructure. This paper will propose a potentially cost-effective non-contact approach for full-field strain and stress mapping using an unmanned aerial vehicle (UAV) mounted with a digital camera and a global positioning system (GPS) tracker. The aim is to use the images acquired by the UAV to define the geometry of the floating cover using photogrammetry. In this manner, any changes in the geometry of the floating cover due to forces acting beneath resulting from its deployment and usage can be determined. The time-scale for these changes is in terms of weeks and months. The change in the geometry can be implemented as input conditions to a finite element model (FEM) for stress prediction. This will facilitate the determination of the state of distress of the floating cover. This paper investigates the possibility of using data recorded from a UAV to predict the strain level and assess the health of such structures. An investigation was first conducted on a laboratory sized membrane structure instrumented with strain gauges for comparison against strains, which were computed from 3D scans of the membrane geometry. Upon validating the technique in the laboratory, it was applied to a more realistic scenario: an outdoor test membrane structure and capable UAV were constructed to see if the shape of the membrane could be computed. The membrane displacements were then used to calculate the membrane stress and strain, state demonstrating a new way to perform structural health monitoring on membrane structures.

  20. Determination of the State of Strain of Large Floating Covers Using Unmanned Aerial Vehicle (UAV Aided Photogrammetry

    Directory of Open Access Journals (Sweden)

    Wern Hann Ong

    2017-07-01

    Full Text Available Floating covers used in waste water treatment plants are one of the many structures formed with membrane materials. These structures are usually large and can spread over an area measuring 470 m × 170 m. The aim of this paper is to describe recent work to develop an innovative and effective approach for structural health monitoring (SHM of such large membrane-like infrastructure. This paper will propose a potentially cost-effective non-contact approach for full-field strain and stress mapping using an unmanned aerial vehicle (UAV mounted with a digital camera and a global positioning system (GPS tracker. The aim is to use the images acquired by the UAV to define the geometry of the floating cover using photogrammetry. In this manner, any changes in the geometry of the floating cover due to forces acting beneath resulting from its deployment and usage can be determined. The time-scale for these changes is in terms of weeks and months. The change in the geometry can be implemented as input conditions to a finite element model (FEM for stress prediction. This will facilitate the determination of the state of distress of the floating cover. This paper investigates the possibility of using data recorded from a UAV to predict the strain level and assess the health of such structures. An investigation was first conducted on a laboratory sized membrane structure instrumented with strain gauges for comparison against strains, which were computed from 3D scans of the membrane geometry. Upon validating the technique in the laboratory, it was applied to a more realistic scenario: an outdoor test membrane structure and capable UAV were constructed to see if the shape of the membrane could be computed. The membrane displacements were then used to calculate the membrane stress and strain, state demonstrating a new way to perform structural health monitoring on membrane structures.

  1. Prevalence and determinants of child maltreatment among high school students in Southern China: A large scale school based survey

    Directory of Open Access Journals (Sweden)

    Chen WQ

    2008-09-01

    Full Text Available Abstract Background Child maltreatment can cause significant physical and psychological problems. The present study aimed to investigate the prevalence and determinants of child maltreatment in Guangzhou, China, where such issues are often considered a taboo subject. Methods A school-based survey was conducted in southern China in 2005. 24 high schools were selected using stratified random sampling strategy based on their districts and bandings. The self-administered validated Chinese version of parent-child Conflict Tactics Scale (CTSPC was used as the main assessment tool to measure the abusive experiences encountered by students in the previous six months. Results The response rate of this survey was 99.7%. Among the 6592 responding students, the mean age was 14.68. Prevalence of parental psychological aggression, corporal punishment, severe and very serve physical maltreatment in the past 6 months were 78.3%, 23.2%, 15.1% and 2.8% respectively. The prevalence of sexual abuse is 0.6%. The most commonly cited reasons for maltreatment included 'disobedience to parents', 'poor academic performance', and 'quarrelling between parents'. Age, parental education, places of origins and types of housing were found to be associated with physical maltreatments whereas gender and fathers' education level were associated with sexual abuse. Conclusion Though largely unspoken, child maltreatment is a common problem in China. Identification of significant determinants in this study can provide valuable information for teachers and health professionals so as to pay special attention to those at-risk children.

  2. CD81 Receptor Regions outside the Large Extracellular Loop Determine Hepatitis C Virus Entry into Hepatoma Cells

    Directory of Open Access Journals (Sweden)

    Pia Banse

    2018-04-01

    Full Text Available Hepatitis C virus (HCV enters human hepatocytes using four essential entry factors, one of which is human CD81 (hCD81. The tetraspanin hCD81 contains a large extracellular loop (LEL, which interacts with the E2 glycoprotein of HCV. The role of the non-LEL regions of hCD81 (intracellular tails, four transmembrane domains, small extracellular loop and intracellular loop is poorly understood. Here, we studied the contribution of these domains to HCV susceptibility of hepatoma cells by generating chimeras of related tetraspanins with the hCD81 LEL. Our results show that non-LEL regions in addition to the LEL determine susceptibility of cells to HCV. While closely related tetraspanins (X. tropicalis CD81 and D. rerio CD81 functionally complement hCD81 non-LEL regions, distantly related tetraspanins (C. elegans TSP9 amd D. melanogaster TSP96F do not and tetraspanins with intermediate homology (hCD9 show an intermediate phenotype. Tetraspanin homology and susceptibility to HCV correlate positively. For some chimeras, infectivity correlates with surface expression. In contrast, the hCD9 chimera is fully surface expressed, binds HCV E2 glycoprotein but is impaired in HCV receptor function. We demonstrate that a cholesterol-coordinating glutamate residue in CD81, which hCD9 lacks, promotes HCV infection. This work highlights the hCD81 non-LEL regions as additional HCV susceptibility-determining factors.

  3. Prevalence and determinants of child maltreatment among high school students in Southern China: a large scale school based survey.

    Science.gov (United States)

    Leung, Phil W S; Wong, William C W; Chen, W Q; Tang, Catherine S K

    2008-09-29

    Child maltreatment can cause significant physical and psychological problems. The present study aimed to investigate the prevalence and determinants of child maltreatment in Guangzhou, China, where such issues are often considered a taboo subject. A school-based survey was conducted in southern China in 2005. 24 high schools were selected using stratified random sampling strategy based on their districts and bandings. The self-administered validated Chinese version of parent-child Conflict Tactics Scale (CTSPC) was used as the main assessment tool to measure the abusive experiences encountered by students in the previous six months. The response rate of this survey was 99.7%. Among the 6592 responding students, the mean age was 14.68. Prevalence of parental psychological aggression, corporal punishment, severe and very serve physical maltreatment in the past 6 months were 78.3%, 23.2%, 15.1% and 2.8% respectively. The prevalence of sexual abuse is 0.6%. The most commonly cited reasons for maltreatment included 'disobedience to parents', 'poor academic performance', and 'quarrelling between parents'. Age, parental education, places of origins and types of housing were found to be associated with physical maltreatments whereas gender and fathers' education level were associated with sexual abuse. Though largely unspoken, child maltreatment is a common problem in China. Identification of significant determinants in this study can provide valuable information for teachers and health professionals so as to pay special attention to those at-risk children.

  4. Post-traumatic stress syndrome in a large sample of older adults: determinants and quality of life.

    Science.gov (United States)

    Lamoureux-Lamarche, Catherine; Vasiliadis, Helen-Maria; Préville, Michel; Berbiche, Djamal

    2016-01-01

    The aims of this study are to assess in a sample of older adults consulting in primary care practices the determinants and quality of life associated with post-traumatic stress syndrome (PTSS). Data used came from a large sample of 1765 community-dwelling older adults who were waiting to receive health services in primary care clinics in the province of Quebec. PTSS was measured with the PTSS scale. Socio-demographic and clinical characteristics were used as potential determinants of PTSS. Quality of life was measured with the EuroQol-5D-3L (EQ-5D-3L) EQ-Visual Analog Scale and the Satisfaction With Your Life Scale. Multivariate logistic and linear regression models were used to study the presence of PTSS and different measures of health-related quality of life and quality of life as a function of study variables. The six-month prevalence of PTSS was 11.0%. PTSS was associated with age, marital status, number of chronic disorders and the presence of an anxiety disorder. PTSS was also associated with the EQ-5D-3L and the Satisfaction with Your Life Scale. PTSS is prevalent in patients consulting in primary care practices. Primary care physicians should be aware that PTSS is also associated with a decrease in quality of life, which can further negatively impact health status.

  5. A review on the use of gas and steam turbine combined cycles as prime movers for large ships. Part I: Background and design

    International Nuclear Information System (INIS)

    Haglind, Fredrik

    2008-01-01

    The aim of the present paper is to review the prospects of using combined cycles as prime movers for large ships, like, container ships, tankers and bulk carriers. The paper is divided into three parts of which this paper constitutes Part I. Here, the environmental and human health concerns of international shipping are outlined. The regulatory framework relevant for shipping and the design of combined cycles are discussed. In Part II, previous work and experience are reviewed, and an overview of the implications of introducing combined cycles as prime movers is included. In Part III, marine fuels are discussed and the pollutant emissions of gas turbines are compared with those of two-stroke, slow-speed diesel engines. Environmental effects of shipping include contributions to the formation of ground-level ozone, acidification, eutrophication and climate impact. Tightening environmental regulations limit the fuel sulphur content and pollutant emissions. For moderate live steam pressures, a vertical HRSG of drum-type mounted directly over the gas turbine, is suggested to be a viable configuration that minimizes ground floor and space requirements

  6. An objective approach to determining the weight ranges of prey preferred by and accessible to the five large African carnivores.

    Directory of Open Access Journals (Sweden)

    Hayley S Clements

    Full Text Available Broad-scale models describing predator prey preferences serve as useful departure points for understanding predator-prey interactions at finer scales. Previous analyses used a subjective approach to identify prey weight preferences of the five large African carnivores, hence their accuracy is questionable. This study uses a segmented model of prey weight versus prey preference to objectively quantify the prey weight preferences of the five large African carnivores. Based on simulations of known predator prey preference, for prey species sample sizes above 32 the segmented model approach detects up to four known changes in prey weight preference (represented by model break-points with high rates of detection (75% to 100% of simulations, depending on number of break-points and accuracy (within 1.3±4.0 to 2.7±4.4 of known break-point. When applied to the five large African carnivores, using carnivore diet information from across Africa, the model detected weight ranges of prey that are preferred, killed relative to their abundance, and avoided by each carnivore. Prey in the weight ranges preferred and killed relative to their abundance are together termed "accessible prey". Accessible prey weight ranges were found to be 14-135 kg for cheetah Acinonyx jubatus, 1-45 kg for leopard Panthera pardus, 32-632 kg for lion Panthera leo, 15-1600 kg for spotted hyaena Crocuta crocuta and 10-289 kg for wild dog Lycaon pictus. An assessment of carnivore diets throughout Africa found these accessible prey weight ranges include 88±2% (cheetah, 82±3% (leopard, 81±2% (lion, 97±2% (spotted hyaena and 96±2% (wild dog of kills. These descriptions of prey weight preferences therefore contribute to our understanding of the diet spectrum of the five large African carnivores. Where datasets meet the minimum sample size requirements, the segmented model approach provides a means of determining, and comparing, the prey weight range preferences of any carnivore

  7. An objective approach to determining the weight ranges of prey preferred by and accessible to the five large African carnivores.

    Science.gov (United States)

    Clements, Hayley S; Tambling, Craig J; Hayward, Matt W; Kerley, Graham I H

    2014-01-01

    Broad-scale models describing predator prey preferences serve as useful departure points for understanding predator-prey interactions at finer scales. Previous analyses used a subjective approach to identify prey weight preferences of the five large African carnivores, hence their accuracy is questionable. This study uses a segmented model of prey weight versus prey preference to objectively quantify the prey weight preferences of the five large African carnivores. Based on simulations of known predator prey preference, for prey species sample sizes above 32 the segmented model approach detects up to four known changes in prey weight preference (represented by model break-points) with high rates of detection (75% to 100% of simulations, depending on number of break-points) and accuracy (within 1.3±4.0 to 2.7±4.4 of known break-point). When applied to the five large African carnivores, using carnivore diet information from across Africa, the model detected weight ranges of prey that are preferred, killed relative to their abundance, and avoided by each carnivore. Prey in the weight ranges preferred and killed relative to their abundance are together termed "accessible prey". Accessible prey weight ranges were found to be 14-135 kg for cheetah Acinonyx jubatus, 1-45 kg for leopard Panthera pardus, 32-632 kg for lion Panthera leo, 15-1600 kg for spotted hyaena Crocuta crocuta and 10-289 kg for wild dog Lycaon pictus. An assessment of carnivore diets throughout Africa found these accessible prey weight ranges include 88±2% (cheetah), 82±3% (leopard), 81±2% (lion), 97±2% (spotted hyaena) and 96±2% (wild dog) of kills. These descriptions of prey weight preferences therefore contribute to our understanding of the diet spectrum of the five large African carnivores. Where datasets meet the minimum sample size requirements, the segmented model approach provides a means of determining, and comparing, the prey weight range preferences of any carnivore species.

  8. Identification and determination of the contribution of iron-steel manufacturing industry to sediment-associated polycyclic aromatic hydrocarbons (PAHs) in a large shallow lake of eastern China.

    Science.gov (United States)

    Zhang, Liu; Bai, Ya-Shu; Wang, Ji-Zhong; Peng, Shu-Chuan; Chen, Tian-Hu; Yin, Da-Qiang

    2016-11-01

    Seventeen polycyclic aromatic hydrocarbon (PAH) compounds were determined in surface sediments collected from the Chaohu Lake (a large shallow lake in eastern China) and its tributaries. Both diagnostic ratios and a receptor model (positive matrix factorization, PMF) were applied to identify and determine the contribution of a local iron-steel manufacturing plant located in the Nanfei River (NFR) to the Chaohu Lake basin. The results show that sites located in the downstream of the steel plant contained concentrations of 17 PAH (Σ 17 PAH) approximately two orders of magnitudes higher than those from other sites. Five factors were identified by the PMF model, including industrial waste, wood/biomass burning, diagenetic origin, domestic coal combustion, and industrial combustion. Our findings suggest that sediments in the downstream of the plant and in the western part of the Chaohu Lake were predominantly affected by industrial coal combustion. A mixture of pyrolytic origins impacted urban sediments in the upstream of the plant, whereas diagenetic origins along with coal and biomass burning were suggested to influence the eastern part and rural tributaries of the lake. To assess the potential ecological risk and toxicity caused by the iron-steel plant, sediment toxicity was evaluated by the PMF model, sediment quality guideline, and toxic equivalent factors. All of the three approaches suggested PAH accumulation in the NFR sediments could produce significant adverse ecological effects and half of the sediment toxicity in the NFR may be attributed to the emissions from the iron-steel plant. Some rural locations also exhibited PAH concentrations above probable effects, most likely contributed by wood/biomass burning.

  9. Determination of hydrogeological conditions in large unconfined aquifer: A case study in central Drava plain (NE Slovenia)

    Science.gov (United States)

    Keršmanc, Teja; Brenčič, Mihael

    2016-04-01

    In several countries, many unregulated landfills exits which releasing harmful contaminations to the underlying aquifer. The Kidričevo industrial complex is located in southeastern part of Drava plain in NW Slovenia. In the past during the production of alumina and aluminum approximately 11.2 million tons of wastes were deposit directly on the ground on two landfills covering an area of 61 hectares. Hydrogeological studies were intended to better characterized conditions bellow the landfill. Geological and hydrogeological conditions of Quaternary unconfined aquifer were analyzed with lithological characterization of well logs and cutting debris and XRF diffraction of silty sediments on 9 boreholes. Hydrogeological conditions: hydraulic permeability aquifer was determined with hydraulic tests and laboratory grain size analyses where empirical USBR and Hazen methods were applied. Dynamics of groundwater was determined by groundwater contour maps and groundwater level fluctuations. The impact of landfill was among chemical analyses of groundwater characterised by electrical conductivity measurements and XRF spectrometry of sand sediments. The heterogeneous Quaternary aquifer composed mainly of gravel and sand, is between 38 m and 47.5 m thick. Average hydraulic permeability of aquifer is within the decade 10-3 m/s. Average hydraulic permeability estimated on grain size curves is 6.29*10-3 m/s, and for the pumping tests is 4.0*10-3 m/s. General direction of groundwater flow is from west to east. During high water status the groundwater flow slightly changes flow direction to the southwest and when pumping station in Kidričevo (NW of landfill) is active groundwater flows to northeast. Landfills have significant impact on groundwater quality.

  10. The prevalence and correlated determinants of hypertension and type 2 diabetes: a large community-based study in Isfahan, Iran

    International Nuclear Information System (INIS)

    Maracy, M.R.; Feizi, A.; Bagherynejad, M

    2012-01-01

    Objective: Despite progress in prevention, detection, treatment and control of hypertension and diabetes, their increasing trend of prevalence remains an important public health problem. In general, only a small proportion of hypertension and diabetes is associated with an underlying disease, i.e. most cases are related to modifiable risk factors. Accordingly, as a large scale community-based study in Iran, the purpose of the present research was to evaluate the prevalence and correlated determinants of hypertension and diabetes among the general population in Isfahan. Methodology: In a cross-sectional study during 2007-2009, 3000 people aged 15-65 years were selected through multi-stage cluster random sampling from the general population in Isfahan. Total and age-sex specific prevalence of hypertension and diabetes were estimated. Multivariate logistic regression was used for studying risk factors and determining their level of association with the risk of hypertension and diabetes simultaneously. Results: The prevalence of hypertension and diabetes was 22.23% and 6.5% respectively among the studied population. Sex specific prevalence of hypertension was 22.4% and 22.06% for women and men, respectively. The corresponding values were 8.27% and 4.86% for diabetes (P < 0.05). Hypertension and diabetes were most prevalent among the age groups of 55-65 years and 45-54 years, respectively. The most important determinants of having hypertension were body mass index (BMI) (P < 0.01), age (P < 0.01), physical activity (P < 0.1) and sex (P < 0.05). Age (P < 0.01), sex (P < 0.05), BMI (P < 0.1), and family history (P < 0.01) were the major determinants of diabetes. Conclusion: The prevalence of diabetes and hypertension was high among the studied population. Furthermore, similar to previous studies, the modifiable risk factors played an important role in their incidence. Therefore, primary prevention is of high importance as a natural extension of hypertension and diabetes

  11. Comparing the life cycle costs of using harvest residue as feedstock for small- and large-scale bioenergy systems (part II)

    International Nuclear Information System (INIS)

    Cleary, Julian; Wolf, Derek P.; Caspersen, John P.

    2015-01-01

    In part II of our two-part study, we estimate the nominal electricity generation and GHG (greenhouse gas) mitigation costs of using harvest residue from a hardwood forest in Ontario, Canada to fuel (1) a small-scale (250 kW e ) combined heat and power wood chip gasification unit and (2) a large-scale (211 MW e ) coal-fired generating station retrofitted to combust wood pellets. Under favorable operational and regulatory conditions, generation costs are similar: 14.1 and 14.9 cents per kWh (c/kWh) for the small- and large-scale facilities, respectively. However, GHG mitigation costs are considerably higher for the large-scale system: $159/tonne of CO 2 eq., compared to $111 for the small-scale counterpart. Generation costs increase substantially under existing conditions, reaching: (1) 25.5 c/kWh for the small-scale system, due to a regulation mandating the continual presence of an operating engineer; and (2) 22.5 c/kWh for the large-scale system due to insufficient biomass supply, which reduces plant capacity factor from 34% to 8%. Limited inflation adjustment (50%) of feed-in tariff rates boosts these costs by 7% to 11%. Results indicate that policy generalizations based on scale require careful consideration of the range of operational/regulatory conditions in the jurisdiction of interest. Further, if GHG mitigation is prioritized, small-scale systems may be more cost-effective. - Highlights: • Generation costs for two forest bioenergy systems of different scales are estimated. • Nominal electricity costs are 14.1–28.3 cents/kWh for the small-scale plant. • Nominal electricity costs are 14.9–24.2 cents/kWh for the large-scale plant. • GHG mitigation costs from displacing coal and LPG are $111-$281/tonne of CO 2 eq. • High sensitivity to cap. factor (large-scale) and labor requirements (small-scale)

  12. Large-scale determinants of diversity across Spanish forest habitats: accounting for model uncertainty in compositional and structural indicators

    Energy Technology Data Exchange (ETDEWEB)

    Martin-Quller, E.; Torras, O.; Alberdi, I.; Solana, J.; Saura, S.

    2011-07-01

    An integral understanding of forest biodiversity requires the exploration of the many aspects it comprises and of the numerous potential determinants of their distribution. The landscape ecological approach provides a necessary complement to conventional local studies that focus on individual plots or forest ownerships. However, most previous landscape studies used equally-sized cells as units of analysis to identify the factors affecting forest biodiversity distribution. Stratification of the analysis by habitats with a relatively homogeneous forest composition might be more adequate to capture the underlying patterns associated to the formation and development of a particular ensemble of interacting forest species. Here we used a landscape perspective in order to improve our understanding on the influence of large-scale explanatory factors on forest biodiversity indicators in Spanish habitats, covering a wide latitudinal and attitudinal range. We considered six forest biodiversity indicators estimated from more than 30,000 field plots in the Spanish national forest inventory, distributed in 213 forest habitats over 16 Spanish provinces. We explored biodiversity response to various environmental (climate and topography) and landscape configuration (fragmentation and shape complexity) variables through multiple linear regression models (built and assessed through the Akaike Information Criterion). In particular, we took into account the inherent model uncertainty when dealing with a complex and large set of variables, and considered different plausible models and their probability of being the best candidate for the observed data. Our results showed that compositional indicators (species richness and diversity) were mostly explained by environmental factors. Models for structural indicators (standing deadwood and stand complexity) had the worst fits and selection uncertainties, but did show significant associations with some configuration metrics. In general

  13. submitter Influence of 3D Effects on Field Quality in the Straight Part of Accelerator Magnets for the High Luminosity Large Hadron Collider

    CERN Document Server

    Nilsson, Emelie; Todesco, Ezio; Enomoto, Shun; Farinon, Stefania; Fabbricatore, Pasquale; Nakamoto, Tatsushi; Sugano, Michinaka; Savary, Frederic

    2017-01-01

    A dedicated D1 beam separation dipole is currently being developed at KEK for the Large Hadron Collider Luminosity upgrade (HL-LHC). Four 150 mm aperture, 5.6 T magnetic field and 6.7 m long Nb-Ti magnets will replace resistive D1 dipoles. The development includes fabrication and testing of 2.2 m model magnets. The dipole has a single layer coil and thin spacers between coil and iron, giving a non-negligible impact of saturation on field quality at nominal field. The magnetic design of the straight section coil cross section is based on 2D optimization and a separate optimization concerns the coil ends. However, magnetic measurements of the short model showed a large difference (tens of units) between the sextupole harmonic in the straight part and the 2D calculation. This difference is correctly modelled only by a 3D analysis: 3D calculations show that the magnetic field quality in the straight part is influenced by the coil ends, even for the 6.7 m long magnets. The effect is even more remarkable in the sho...

  14. submitter Influence of 3D Effects on Field Quality in the Straight Part of Accelerator Magnets for the High Luminosity Large Hadron Collider

    CERN Document Server

    Nilsson, Emelie; Todesco, Ezio; Enomoto, Shun; Farinon, Stefania; Fabbricatore, Pasquale; Nakamoto, Tatsushi; Sugano, Michinaka; Savary, Frederic

    2018-01-01

    A dedicated D1 beam separation dipole is currently being developed at KEK for the Large Hadron Collider Luminosity upgrade (HL-LHC). Four 150 mm aperture, 5.6 T magnetic field and 6.7 m long Nb-Ti magnets will replace resistive D1 dipoles. The development includes fabrication and testing of 2.2 m model magnets. The dipole has a single layer coil and thin spacers between coil and iron, giving a non-negligible impact of saturation on field quality at nominal field. The magnetic design of the straight section coil cross section is based on 2D optimization and a separate optimization concerns the coil ends. However, magnetic measurements of the short model showed a large difference (tens of units) between the sextupole harmonic in the straight part and the 2D calculation. This difference is correctly modelled only by a 3D analysis: 3D calculations show that the magnetic field quality in the straight part is influenced by the coil ends, even for the 6.7 m long magnets. The effect is even more remarkable in the sho...

  15. Modelling of natural convection flows with large temperature differences: a benchmark problem for low Mach number solvers. Part. 1 reference solutions

    International Nuclear Information System (INIS)

    Le Quere, P.; Weisman, C.; Paillere, H.; Vierendeels, J.; Dick, E.; Becker, R.; Braack, M.; Locke, J.

    2005-01-01

    Heat transfer by natural convection and conduction in enclosures occurs in numerous practical situations including the cooling of nuclear reactors. For large temperature difference, the flow becomes compressible with a strong coupling between the continuity, the momentum and the energy equations through the equation of state, and its properties (viscosity, heat conductivity) also vary with the temperature, making the Boussinesq flow approximation inappropriate and inaccurate. There are very few reference solutions in the literature on non-Boussinesq natural convection flows. We propose here a test case problem which extends the well-known De Vahl Davis differentially heated square cavity problem to the case of large temperature differences for which the Boussinesq approximation is no longer valid. The paper is split in two parts: in this first part, we propose as yet unpublished reference solutions for cases characterized by a non-dimensional temperature difference of 0.6, Ra 10 6 (constant property and variable property cases) and Ra = 10 7 (variable property case). These reference solutions were produced after a first international workshop organized by Cea and LIMSI in January 2000, in which the above authors volunteered to produce accurate numerical solutions from which the present reference solutions could be established. (authors)

  16. Large-scale determinants of intestinal schistosomiasis and intermediate host snail distribution across Africa: does climate matter?

    Science.gov (United States)

    Stensgaard, Anna-Sofie; Utzinger, Jürg; Vounatsou, Penelope; Hürlimann, Eveline; Schur, Nadine; Saarnak, Christopher F L; Simoonga, Christopher; Mubita, Patricia; Kabatereine, Narcis B; Tchuem Tchuenté, Louis-Albert; Rahbek, Carsten; Kristensen, Thomas K

    2013-11-01

    The geographical ranges of most species, including many infectious disease agents and their vectors and intermediate hosts, are assumed to be constrained by climatic tolerances, mainly temperature. It has been suggested that global warming will cause an expansion of the areas potentially suitable for infectious disease transmission. However, the transmission of infectious diseases is governed by a myriad of ecological, economic, evolutionary and social factors. Hence, a deeper understanding of the total disease system (pathogens, vectors and hosts) and its drivers is important for predicting responses to climate change. Here, we combine a growing degree day model for Schistosoma mansoni with species distribution models for the intermediate host snail (Biomphalaria spp.) to investigate large-scale environmental determinants of the distribution of the African S. mansoni-Biomphalaria system and potential impacts of climatic changes. Snail species distribution models included several combinations of climatic and habitat-related predictors; the latter divided into "natural" and "human-impacted" habitat variables to measure anthropogenic influence. The predictive performance of the combined snail-parasite model was evaluated against a comprehensive compilation of historical S. mansoni parasitological survey records, and then examined for two climate change scenarios of increasing severity for 2080. Future projections indicate that while the potential S. mansoni transmission area expands, the snail ranges are more likely to contract and/or move into cooler areas in the south and east. Importantly, we also note that even though climate per se matters, the impact of humans on habitat play a crucial role in determining the distribution of the intermediate host snails in Africa. Thus, a future contraction in the geographical range size of the intermediate host snails caused by climatic changes does not necessarily translate into a decrease or zero-sum change in human

  17. Determining the correlation of Epstein-Barr virus with diffuse large B-cell lymphoma by chromogenic in situ hybridization

    Directory of Open Access Journals (Sweden)

    Kosari F

    2012-09-01

    Full Text Available Background: Diffuse large B-cell lymphoma (DLBCL is the most common type of lymphoma. There are various types of DLBCL including immunoblastic and centroblastic. Epstein-Barr virus (EBV is a member of Herpes virus family found in all human populations inducing different lymphoproliferative disorders. The role of EBV in the development of DLBCL is known. Multiple laboratory methods are available for detecting EBV. This study was conducted to determine the correlation of EBV with DLBCL in samples referred to pathology ward in Shariati and Sina Hospitals by chromogenic in situ hybridization (CISH method.Methods: In this case/control study, pathological specimens of 50 patients with DLBCL as well as 50 reactive lymph nodes and tonsils (control group were collected from archives of Shariati and Sina Hospitals and were evaluated for EBV encoded RNA (EBER expression based on CISH method. A peptide nucleic acid (PNA EBV probe (Dakocytomatin was used while all the processes were done in RNAase-free conditions using RNAase-free water, sterile gloves and samplers. Results: Out of fifty specimens in the case group, eight were positive for EBER in comparison with two in the control group (P=0.046. No statistically significant difference was observed between intranodal or extranodal samples (P=0.736 or between males and females (P=0.0746.Conclusion: Our study showed that EBV positivity for EBER in patient with DLBCL could be determined more effectively by CISH method than immunohistochemistry (IHC. Comparative analysis between CISH, PCR and IHC methods is recommended.

  18. Nuclear fuel technology - Determination of uranium in solutions, uranium hexafluoride and solids - Part 2: Iron(II) reduction/cerium(IV) oxidation titrimetric method

    International Nuclear Information System (INIS)

    2004-01-01

    This first edition of ISO 7097-1 together with ISO 7097-2:2004 cancels and replaces ISO 7097:1983, which has been technically revised, and ISO 9989:1996. ISO 7097 consists of the following parts, under the general title Nuclear fuel technology - Determination of uranium in solutions, uranium hexafluoride and solids: Part 1: Iron(II) reduction/potassium dichromate oxidation titrimetric method; Part 2: Iron(II) reduction/cerium(IV) oxidation titrimetric method. This part 2. of ISO 7097 describes procedures for determination of uranium in solutions, uranium hexafluoride and solids. The procedures described in the two independent parts of this International Standard are similar: this part uses a titration with cerium(IV) and ISO 7097-1 uses a titration with potassium dichromate

  19. Nuclear fuel technology - Determination of uranium in solutions, uranium hexafluoride and solids - Part 1: Iron(II) reduction/potassium dichromate oxidation titrimetric method

    International Nuclear Information System (INIS)

    2004-01-01

    This first edition of ISO 7097-1 together with ISO 7097-2:2004 cancels and replaces ISO 7097:1983, which has been technically revised, and ISO 9989:1996. ISO 7097 consists of the following parts, under the general title Nuclear fuel technology - Determination of uranium in solutions, uranium hexafluoride and solids: Part 1: Iron(II) reduction/potassium dichromate oxidation titrimetric method; Part 2: Iron(II) reduction/cerium(IV) oxidation titrimetric method. This part 1. of ISO 7097 describes procedures for the determination of uranium in solutions, uranium hexafluoride and solids. The procedures described in the two independent parts of this International Standard are similar: this part uses a titration with potassium dichromate and ISO 7097-2 uses a titration with cerium(IV)

  20. Determination of residual oil saturation from time-lapse pulsed neutron capture logs in a large sandstone reservoir

    International Nuclear Information System (INIS)

    Syed, E.V.; Salaita, G.N.; McCaffery, F.G.

    1991-01-01

    Cased hole logging with pulsed neutron tools finds extensive use for identifying zones of water breakthrough and monitoring oil-water contacts in oil reservoirs being depleted by waterflooding or natural water drive. Results of such surveys then find direct use for planning recompletions and water shutoff treatments. Pulsed neutron capture (PNC) logs are useful for estimating water saturation changes behind casing in the presence of a constant, high-salinity environment. PNC log surveys run at different times, i.e., in a time-lapse mode, are particularly amenable to quantitative analysis. The combined use of the original open hole and PNC time-lapse log information can then provide information on remaining or residual oil saturations in a reservoir. This paper reports analyses of historical pulsed neutron capture log data to assess residual oil saturation in naturally water-swept zones for selected wells from a large sandstone reservoir in the Middle East. Quantitative determination of oil saturations was aided by PNC log information obtained from a series of tests conducted in a new well in the same field

  1. Use of allele-specific FAIRE to determine functional regulatory polymorphism using large-scale genotyping arrays.

    Directory of Open Access Journals (Sweden)

    Andrew J P Smith

    Full Text Available Following the widespread use of genome-wide association studies (GWAS, focus is turning towards identification of causal variants rather than simply genetic markers of diseases and traits. As a step towards a high-throughput method to identify genome-wide, non-coding, functional regulatory variants, we describe the technique of allele-specific FAIRE, utilising large-scale genotyping technology (FAIRE-gen to determine allelic effects on chromatin accessibility and regulatory potential. FAIRE-gen was explored using lymphoblastoid cells and the 50,000 SNP Illumina CVD BeadChip. The technique identified an allele-specific regulatory polymorphism within NR1H3 (coding for LXR-α, rs7120118, coinciding with a previously GWAS-identified SNP for HDL-C levels. This finding was confirmed using FAIRE-gen with the 200,000 SNP Illumina Metabochip and verified with the established method of TaqMan allelic discrimination. Examination of this SNP in two prospective Caucasian cohorts comprising 15,000 individuals confirmed the association with HDL-C levels (combined beta = 0.016; p = 0.0006, and analysis of gene expression identified an allelic association with LXR-α expression in heart tissue. Using increasingly comprehensive genotyping chips and distinct tissues for examination, FAIRE-gen has the potential to aid the identification of many causal SNPs associated with disease from GWAS.

  2. Large Scale Applications Using FBG Sensors: Determination of In-Flight Loads and Shape of a Composite Aircraft Wing

    Directory of Open Access Journals (Sweden)

    Matthew J. Nicolas

    2016-06-01

    Full Text Available Technological advances have enabled the development of a number of optical fiber sensing methods over the last few years. The most prevalent optical technique involves the use of fiber Bragg grating (FBG sensors. These small, lightweight sensors have many attributes that enable their use for a number of measurement applications. Although much literature is available regarding the use of FBGs for laboratory level testing, few publications in the public domain exist of their use at the operational level. Therefore, this paper gives an overview of the implementation of FBG sensors for large scale structures and applications. For demonstration, a case study is presented in which FBGs were used to determine the deflected wing shape and the out-of-plane loads of a 5.5-m carbon-composite wing of an ultralight aerial vehicle. The in-plane strains from the 780 FBG sensors were used to obtain the out-of-plane loads as well as the wing shape at various load levels. The calculated out-of-plane displacements and loads were within 4.2% of the measured data. This study demonstrates a practical method in which direct measurements are used to obtain critical parameters from the high distribution of FBG sensors. This procedure can be used to obtain information for structural health monitoring applications to quantify healthy vs. unhealthy structures.

  3. Large Isoform of Mammalian Relative of DnaJ is a Major Determinant of Human Susceptibility to HIV-1 Infection

    Directory of Open Access Journals (Sweden)

    Yu-Ping Chiang

    2014-12-01

    Full Text Available Individual differences in susceptibility to human immunodeficiency virus type 1 (HIV-1 infection have been of interest for decades. We aimed to determine the contribution of large isoform of Mammalian DnaJ (MRJ-L, a HIV-1 Vpr-interacting cellular protein, to this natural variation. Expression of MRJ-L in monocyte-derived macrophages was significantly higher in HIV-infected individuals (n = 31 than their uninfected counterparts (n = 27 (p = 0.009. Fifty male homosexual subjects (20 of them are HIV-1 positive were further recruited to examine the association between MRJ-L levels and occurrence of HIV infection. Bayesian multiple logistic regression revealed that playing a receptive role and increased levels of MRJ-L in macrophages were two risk factors for HIV-1 infection. A 1% rise in MRJ-L expression was associated with a 1.13 fold (95% CrI 1.06–1.29 increase in odds of contracting HIV-1 infection. Ex vivo experiments revealed that MRJ-L facilitated Vpr-dependent nuclear localization of virus. Infection of macrophage-tropic strain is a critical step in HIV-1 transmission. MRJ-L is a critical factor in this process; hence, subjects with higher macrophage MRJ-L levels are more vulnerable to HIV-1 infection.

  4. Determination antimicrobial resistance profile of Acinetobacter strains isolated from hospitalized patients in Different Part of Taleghani Hospital (Ahvaz, Iran

    Directory of Open Access Journals (Sweden)

    Khadijah Ahmadi

    2014-10-01

    Full Text Available Background: The members of the genus Acinetobacter are Gram-negative cocobacilli that are frequently found in the environment but also in the hospital setting where they have been associated with outbreaks of nosocomial infections such as meningitis, endocarditis, skin and soft tissue infections, urinary tract infection, conjunctivitis, burn wound infection and bacteremia. This organism has been shown resistance to different antimicrobial agents. The aim of this study was to determination antibiotic resistance profile of Acinetobacter strains isolated from hospitalized patients in Taleghani hospital (Ahvaz, Iran. Materials and Methods: This cross-sectional study was conducted on 43 Acinetobacter strains isolated from hospitalized patients. Clinical specimens were cultured on microbiological media. Subsequently, drug susceptibility test was performed using the disc diffusion method according to CLSI recommendations. Results: Acinetobacter strains were isolated from different specimens consisting biopsy 24 (55.8%, wound 13 (30/2% and blood 6 (14%. In antimicrobial susceptibility testing, colistin exhibited the greatest activity (60.5% against isolated strains. 33 (76/7% isolates demonstrated resistance to imipenem. Conclusion: In outbreak situations, surveillance cultures of patients involved in the outbreak or who are deemed at risk for colonization/infection with the outbreak organism are often parts of the planned intervention.

  5. FORECASTING OF PRODUCTION OUTPUT FOR LIGHT INDUSTRY ENTERPRISES WITH PURPOSE TO DETERMINE THEIR POWER RESOURCES REQUIREMENTS. Part 1

    Directory of Open Access Journals (Sweden)

    V. N. Romaniuk

    2015-01-01

    Full Text Available The paper presents an interest for those specialists who are involved in solution of efficiency problems in light industry of Belarus as one of the significant industries that forms an economic situation in the Republic, its export potential and social climate. It is extremely relevant for the Belarusian enterprises to reduce production costs in order to preserve and strengthen positions in the light industry market. Operating capacities for production of natural, synthetic textile and knit-wear materials and their subsequent treatment are in many respects unjustifiably energy intensive. Nowadays the only acceptable solution of the problem for reduction of production costs is to decrease its energy component. Such approach requires transition to creation of modern heat and power supply systems at heat technology enterprises.The most important sub-system of the enterprises is own combined production of energy flows of secondary electrical and heat energy, freeze. There is a complex of problems that arise during designing process of tri-generation unit. One of the most important problems presupposes determination of a base load demand and capacity of every energy flow generated by an energy source. The solution is directly related to production output, which in its turn is determined by the requirements of sales markets. Due to various reasons the markets have their own specificity for the enterprises under consideration. It is proposed to use statistical methods for searching requirements. In this connection it is necessary to take into account industry development rate (pre-determined by State Programs, Plans, Governmental solutions, including directive instructions, production volumes of competitive goods and actual goods situation on the sales market.The paper presents the first part of the executed complex investigations which are directed on the development of scientifically-substantiated proposals for higher energy efficiency of the

  6. FORECASTING OF PRODUCTION OUTPUT FOR LIGHT INDUSTRY ENTERPRISES WITH PURPOSE TO DETERMINE THEIR POWER RESOURCES REQUIREMENTS. Part 2

    Directory of Open Access Journals (Sweden)

    V. N. Romaniuk

    2015-01-01

    Full Text Available The proposed paper is a continuation of the work, published in the previous issue. It is destined for specialists who are engaged in solution of problems pertaining to efficiency of light industry in Belarus which is considered as one of the branches being significantly involved in formation of national economy, its export potential and social climate. It is extremely relevant to reduce production costs in order to preserve and add strength to the branch positions in the markets. Production of natural, synthetic and knitted materials and their subsequent treatment are unreasonably power-consuming processes. Fundamental solution of the problem for reduction of production costs is to decrease its energy component and this can be achieved due to transition to modern heat and power systems in technological complexes of enterprises.The first part of the paper has considered a range of issues that served as a basis for obtaining statistical models in order to forecast the required production volume of main knitted and textile materials.  Forecasting has been prepared   for a period of more than 20 years because it has been predetermined by development horizon of comprehensive modernization of energy supply systems at enterprises of light industry. The production volumes essentially differ from those that have been stipulated in the programs of light industry.The present paper shows selection of statistical game-type for determination of  build-up rate of the production volume for every textile enterprise. The so-called “Game with Nature” has been selected as a game which is widely used for solution of analogous demand problems. The statistical forecasting models of production obtained in the first part are applied in the second part of the paper which considers strategies for development of individual enterprises. JSC :Baranovichi Industrial Cotton Association” has been taken an example in the paper. Production volumes of any enterprise are

  7. A see-saw of pre-Columbian boom regions in southern Peru, determined by large-scale circulation changes

    Science.gov (United States)

    Mächtle, B.; Schittek, K.; Forbriger, M.; Schäbitz, F.; Eitel, B.

    2012-04-01

    Environmental changes and cultural transitions during several periods of Peruvian history show a strong coincidence between humid and dry climatic oscillations and the rise and decline of cultures. It is noteworthy, that alternating periods of geo-ecological fragility and stability occurred in time and space between the coastal Nasca region (14.5° S) and the high Andean northern Titicaca basin, just a few hundred kilometers to the east. Based on a multi-proxy palynological and sedimentological approach to reconstruct palaeoenvironmental changes, we found that the Nasca region received a maximum of precipitation during the archaeological boom times of the Early Horizon and the Early Intermediate Period (800 BC - 650 AD, Paracas and Nasca cultures) as well as during the late intermediate period (1150-1450 AD), whereas, in contrast, the Titicaca region further to the south-east experienced drought and cultural depression during that times. During the Middle Horizon (650 - 1150 AD), the Tiwanaku agronomy and culture boomed in the Titicaca region and expanded to the west, contemporaneous with a raised lake level and more humid conditions. In the Nasca region, runoff for irrigation purposes was reduced and less reliable due to drought. Considering a coincidence between environmental and cultural changes, we state that success and decline of civilizations were controlled by hydrological oscillations, triggering fertility as well as a critical loss of natural resources. In response to spatial changing resources, cultural foci were shifted. Therefore, the success of pre-Columbian civilizations was closely coupled to areas of geo-ecological favorability, which were directly controlled by distinct regional impacts of large-scale circulation mechanisms, including El Niño - Southern Oscillation (ENSO). Changes in the position of the intertropical convergence zone (ITCZ) and the Bolivian anticyclone determined meridional shifts in moisture transport across the Andes, which

  8. Fetal Environment Is a Major Determinant of the Neonatal Blood Thyroxine Level: Results of a Large Dutch Twin Study.

    Science.gov (United States)

    Zwaveling-Soonawala, Nitash; van Beijsterveldt, Catharina E M; Mesfum, Ertirea T; Wiedijk, Brenda; Oomen, Petra; Finken, Martijn J J; Boomsma, Dorret I; van Trotsenburg, A S Paul

    2015-06-01

    The interindividual variability in thyroid hormone function parameters is much larger than the intraindividual variability, suggesting an individual set point for these parameters. There is evidence to suggest that environmental factors are more important than genetic factors in the determination of this individual set point. This study aimed to quantify the effect of genetic factors and (fetal) environment on the early postnatal blood T4 concentration. This was a classical twin study comparing the resemblance of neonatal screening blood T4 concentrations in 1264 mono- and 2566 dizygotic twin pairs retrieved from the population-based Netherlands Twin Register. Maximum-likelihood estimates of variance explained by genetic and environmental influences were obtained by structural equation modeling in data from full-term and preterm twin pairs. In full-term infants, genetic factors explained 40%/31% of the variance in standardized T4 scores in boys/girls, and shared environment, 27%/22%. The remaining variance of 33%/47% was due to environmental factors not shared by twins. For preterm infants, genetic factors explained 34%/0% of the variance in boys/girls, shared environment 31%/57%, and unique environment 35%/43%. In very preterm twins, no significant contribution of genetic factors was observed. Environment explains a large proportion of the resemblance of the postnatal blood T4 concentration in twin pairs. Because we analyzed neonatal screening results, the fetal environment is the most likely candidate for these environmental influences. Genetic influences on the T4 set point diminished with declining gestational age, especially in girls. This may be due to major environmental influences such as immaturity and nonthyroidal illness in very preterm infants.

  9. An alternative method for determining particle-size distribution of forest road aggregate and soil with large-sized particles

    Science.gov (United States)

    Hakjun Rhee; Randy B. Foltz; James L. Fridley; Finn Krogstad; Deborah S. Page-Dumroese

    2014-01-01

    Measurement of particle-size distribution (PSD) of soil with large-sized particles (e.g., 25.4 mm diameter) requires a large sample and numerous particle-size analyses (PSAs). A new method is needed that would reduce time, effort, and cost for PSAs of the soil and aggregate material with large-sized particles. We evaluated a nested method for sampling and PSA by...

  10. Determining personal talents and behavioral styles of applicants to surgical training: a new look at an old problem, part II.

    Science.gov (United States)

    Bell, Richard M; Fann, Stephen A; Morrison, James E; Lisk, J Ryan

    2012-01-01

    The selection of applicants for training in any particular surgical program is an imprecise exercise. Despite the abundance of information on particular candidates, many of the fundamental qualities that are associated with success for the surgical trainee cannot be identified by review of the applicants' grades, scores, letters of recommendation, personal statement, or even from the interview process. We sought a method to determine behavior, motivation, and values possessed by applicants that coincided with traits by our current residents who had demonstrated success in our program. The methods have been described in detail in Part I.(1) Briefly, the individual applicants' personal talent report was used to develop a rank-ordered list by the outside consultant and was compared to the traditionally developed rank list developed by the Department in the traditional fashion and the newly developed job benchmark. Five hundred thirty-five applications were received and interviews were offered to 112 (21%) applicants. Seventy-five on-line surveys were completed by the 77 applicants who were interviewed. The consultant was able to identify important personal talents, elements of motivation, and behavioral style that were not gleaned from the application or the interview process, some of which prompted a revision of our final ranking order.(1) This report discusses the results of the motivational analysis and of the Personal Talents Skills Inventory. Applicants with a strong motivation for the theoretical (knowledge) and social commitment (desire to help others) are important characteristics. Clear views of the external world and of self, as well as a sense of satisfaction with the applicants' vision of their future are positively associated with success in our program. The ability to identify unique behavioral, motivational and personal talents that applicants bring to the program that were not identifiable from the traditional application and interview process has

  11. Determination of radon in soil and water in parts of Accra, and generation of preliminary radon map for Ghana

    International Nuclear Information System (INIS)

    Osei, Peter

    2016-07-01

    The research was focused on determining the radon levels in soil and water in parts of Accra, generate a preliminary radon map for Ghana and estimate a pilot reference level for the country, using the data obtained from this research and collated data from other researchers. The radon gas measurement was done with the passive method, using the SSNTDs which are sensitive to alpha particles emitted by radon. Cellulose nitrate LR – 115 type II alpha particle detectors were used. The detectors were chemically etched in a 2.5 M NaOH solution at a temperature of 60 °C for 90 minutes, after two weeks and two months of exposure to soil and water respectively. The images of the etched detectors were acquired by means of a scanner and then tracks counted with ImageJ software. Inverse Distance Weighing (IDW) method of ArcGIS 10.2 was used to spatially distribute the radon concentration on a map. The average soil radon concentration in the study area ranges from 0.191 kBqm"-"3 to 3.416 kBqm"-"3 with a mean of 1.193 kBqm"-"3. The radon concentration in water from the study area ranges from 0.00346 BqL"-"1 to 0.00538 BqL"-"1 with an average of 0.00456 BqL"-"1. A strong negative correlation has been established between radon in soil and water in the study area. The preliminary national average indoor, water and soil radon concentrations are 137 Bqm"-"3, 361.93 Bqm"-"3 and 3716.74 Bqm"-"3 respectively. The average levels of water and indoor radon exceeded WHO’s reference level of 100 Bqm"-"3. Accordingly, the pilot national indoor radon reference level for Ghana is set as 200 Bqm"-"3. (au)

  12. Methodology for calculating the thickness free of sigma phase in duplex stainless steels large section parts during hiperquenching; Metodologia para el calculo de espesores limite libres de fase sigma durante el hipertemple en piezas de aceros duplex de gran seccion

    Energy Technology Data Exchange (ETDEWEB)

    Jimbert, P.; Guraya, T.; Torregary, A.; Bravo, P.

    2013-06-01

    To achieve the mechanical properties and corrosion resistance desired by duplex stainless steels used by the petrochemical and nuclear industry, parts are subjected to a hiperquenching heat treatment from about 1050 degree centigrade. This avoids the risk of intermetallic precipitation which drastically reduces the properties of these materials. However with increasing depth to which the deposits are present, the thicknesses for such pipes have been increased, resulting in higher levels of demand on all its manufacturing process, including the heat treatment. To avoid the precipitation of intermetallic phases such as sigma phase it is necessary to know the cooling profile in the center of the work piece and for this purpose to know the value of the Surface Heat Transfer Coefficient (h) is essential. This coefficient changes during the hiperquenching and its value is determined experimentally as it depends on several process parameters. Studies reveal that its value is stabilized within a few seconds. We can then assume that to know the cooling profile in the center of large sections it is only necessary to know the stabilized value of h. However, all the studies found in the literature are referred to diameters smaller than 100 mm. This paper has developed a methodology to predict the precipitation of intermetallic phases in duplex stainless steel parts with large thicknesses in industrial facilities from the calculation of h. This methodology allows us to calculate the cooling profiles without wasting any work piece using one or more sensorized patterns with thermocouples and a subsequent simulation with ANSYS. (Author)

  13. Study of High-Resolution Spectroscopy of Plutonium. Part I. Contribution to the Classification of the Arc Spectrum. Part II. Determination of the Magnetic Moment of 239Pu

    International Nuclear Information System (INIS)

    Gerstenkorn, S.

    1962-01-01

    The study of the hyperfine structure and isotope shift enabled the positions of the first five levels of the multiplet 7 F 0-6 belonging to the fundamental configuration 5f 6 7s 2 to be determined. The classification of the arc spectrum begun in this way led to 25 odd levels, the number of classified lines (70) representing about 30 p. 100 of the light emitted by this hollow cathode in the visible. In addition, the isotope shifts of many lines and the data given by the King furnace show that the first levels of the configuration 5f 5 6d7s 2 are also low less than 8000 cm -1 above the fundamental level 7 F 0 . The proximity of the configuration f 6 s 2 and f 5 ds 2 shows that the bonding energies of the 5f and 6d electrons are of the same order of magnitude and this fact must be responsible for the multiple valences belonging to plutonium. From the hyperfine structure of spark lines (Pu II) the interval factor a 7 for the electron was deduced giving for the calculated nuclear moment of 239 Pu a value of +0.21 ±0.06 μ N . The position of the hyperfine components show that the nuclear moment is positive, although the theoretical value given by B. R. Mottelson and S. Nillson is negative and equal to -0.1 μ N . (author) [fr

  14. An Objective Approach to Determining the Weight Ranges of Prey Preferred by and Accessible to the Five Large African Carnivores

    OpenAIRE

    Clements, Hayley S.; Tambling, Craig J.; Hayward, Matt W.; Kerley, Graham I. H.

    2014-01-01

    Broad-scale models describing predator prey preferences serve as useful departure points for understanding predator-prey interactions at finer scales. Previous analyses used a subjective approach to identify prey weight preferences of the five large African carnivores, hence their accuracy is questionable. This study uses a segmented model of prey weight versus prey preference to objectively quantify the prey weight preferences of the five large African carnivores. Based on simulations of kno...

  15. A new method for the determination of the real part of the hadron elastic scattering amplitude at small angles and high energies

    Energy Technology Data Exchange (ETDEWEB)

    Gauron, P. [Theory Group, Laboratoire de Physique Nucleaire et des Hautes Energies (LPNHE), CNRS, and Universite Pierre et Marie Curie, Paris (France)]. E-mail: gauron@in2p3.fr; Nicolescu, B. [Theory Group, Laboratoire de Physique Nucleaire et des Hautes Energies (LPNHE), CNRS, and Universite Pierre et Marie Curie, Paris (France)]. E-mail: nicolesc@lpnhep.in2p3.fr; Selyugin, O.V. [BLTP, JINR, Dubna, Moscow region (Russian Federation)]. E-mail: selugin@thsun1.jinr.ru

    2005-11-24

    A new method for the determination of the real part of the elastic scattering amplitude is examined for high energy proton-proton at small momentum transfer. This method allows us to decrease the number of model assumptions, to obtain the real part in a narrow region of momentum transfer and to test different models. The real part is computed at a given point t{sub min} near t=0 from the known Coulomb amplitude. Hence one obtains an important constraint on the real part of the forward scattering amplitude and therefore on the {rho}-parameter (measuring the ratio of the real to imaginary part of the scattering amplitude at t=0), which can be tested at LHC.

  16. Climatological studies on precipitation features and large-scale atmospheric fields on the heavy rainfall days in the eastern part of Japan from the Baiu to midsummer season

    Science.gov (United States)

    Matsumoto, Kengo; Kato, Kuranoshin; Otani, Kazuo

    2017-04-01

    In East Asia the significant subtropical frontal zone called the Meiyu (in China) / Baiu (in Japan) appears in early summer (just before the midsummer) and the huge rainfall is brought due to the frequent appearance of the "heavy rainfall days" (referred to as HRDs hereafter) mainly in that western part. On the other hand, large-scale fields around the front in eastern Japan is rather different from that in western Japan but the total precipitation in the eastern Japan is still considerable compared to that in the other midlatitude regions. Thus, it is also interesting to examine how the rainfall characteristics and large-scale atmospheric fields on HRDs (with more than 50 mm/day) in the eastern Japan in the mature stage of the Baiu season (16 June 15 July), together with those in midsummer (1 31 August). Based on such scientific background, further analyses were performed in this study mainly with the daily and the hourly precipitation data and the NCEP/NCAR re-analysis date from 1971 to 2010, succeeding to our previous results (e.g., EGU2015). As reported at EGU2014 and 2015, about half of HRDs at Tokyo (eastern Japan) were related to the typhoon even in the Baiu season. Interestingly, half of HRDs were characterized by the large contribution of moderate rain less than 10 mm/h. While, the precipitation on HRDs at Tokyo in midsummer was mainly brought by the intense rainfall with more than 10 mm/h, in association with the typhoons. In the present study, we examined the composite meridional structure of the rainfall area along 140E. In the pattern only associated with a typhoons in the Baiu season (Pattern A), the heavy rainfall area (more than 50 mm/day) with large contribution of the intense rain (stronger than 10 mm/h) showed rather wide meridional extension. The area was characterized by the duration of the intermittent enhancement of the rainfall. In the pattern associated with a typhoon and a front (Pattern B), while the contribution ratio of the rainfall

  17. Lisímetro de pesagem de grande porte. parte II: consumo hídrico do coqueiro anão verde irrigado Large-scale weighing lysimeter. part II: water requirements of the irrigated dwarf-green coconut

    Directory of Open Access Journals (Sweden)

    Inajá F. Sousa

    2011-05-01

    Full Text Available Este trabalho, como segunda parte de uma pesquisa realizada no Estado de Sergipe, objetiva determinar a evapotranspiração e o coeficiente de cultura na fase de crescimento do coqueiro anão-verde (Cocos nucifera L., com base em medições lisimétricas e no modelo do balanço de energia, segundo a razão de Bowen. Obteve-se a evapotranspiração de referência pelo método de Penman-Monteith, na escala diária em todo o período experimental. O sistema de aquisição de dados foi programado para a automação da coleta de todos os sensores necessários à obtenção dos componentes do balanço de energia. O consumo hídrico do coqueiro durante a fase de crescimento é de 1.263,30 mm, com média diária de 3,90 mm d-1. O coeficiente de cultura nessa fase fenológica da palmeira varia entre 0,50 e 1,80, com média de 0,96.This paper, as Part II of a research carried out in Sergipe state, aims to determine evapotranspiration and crop coefficient of dwarf-green coconut (Cocos nucifera L. based on lysimeter measurements and Bowen ratio-energy balance method. The reference evapotranspiration was obtained by the Penman-Monteith approach on daily-scale during the experimental period. The data acquisition system was used to obtain all data from the sensors necessary to determine the energy balance components. The water requirements of coconut palm during the phenological growth stage is 1263.30 mm, with daily average of 3.90 mm d-1. The crop coefficient during this phenological growth stage varies between 0.50 and 1.80, with daily mean of 0.96.

  18. Trophic gradients in a large-river delta: Ecological structure determined by connectivity gradients in the Danube Delta (Romania)

    NARCIS (Netherlands)

    Coops, H.; Buijse-Bogdan, L.L.; Buijse, A.D.; Constantinescu, A.; Covaliov, S.; Hanganu, J.; Ibelings, B.W.; Menting, G.; Navodaru, I.; Oosterberg, W.; Staras, M.; Torok, L.

    2008-01-01

    There are over 300 lakes interconnected by riverbranches and man-made canals in the Danube Delta (Romania). A multidisciplinary survey of these riverine lakes situated in large Wetland complexes was made comprising hydrological modelling, remote sensing and monitoring of water quality, plankton,

  19. Whole effluent assessment of industrial wastewater for determination of BAT compliance. Part 2: metal surface treatment industry.

    Science.gov (United States)

    Gartiser, Stefan; Hafner, Christoph; Hercher, Christoph; Kronenberger-Schäfer, Kerstin; Paschke, Albrecht

    2010-06-01

    Toxicity testing has become a suitable tool for wastewater evaluation included in several reference documents on best available techniques of the Integrated Pollution Prevention and Control (IPPC) Directive. The IPPC Directive requires that for direct dischargers as well as for indirect dischargers, the same best available techniques should be applied. Within the study, the whole effluent assessment approach of OSPAR has been applied for determining persistent toxicity of indirectly discharged wastewater from the metal surface treatment industry. Twenty wastewater samples from the printed circuit board and electroplating industries which indirectly discharged their wastewater to municipal wastewater treatment plants (WWTP) have been considered in the study. In all factories, the wastewater partial flows were separated in collecting tanks and physicochemically treated in-house. For assessing the behaviour of the wastewater samples in WWTPs, all samples were biologically pretreated for 7 days in the Zahn-Wellens test before ecotoxicity testing. Thus, persistent toxicity could be discriminated from non-persistent toxicity caused, e.g. by ammonium or readily biodegradable compounds. The fish egg test with Danio rerio, the Daphnia magna acute toxicity test, the algae test with Desmodesmus subspicatus, the Vibrio fischeri assay and the plant growth test with Lemna minor have been applied. All tests have been carried out according to well-established DIN or ISO standards and the lowest ineffective dilution (LID) concept. Additionally, genotoxicity was tested in the umu assay. The potential bioaccumulating substances (PBS) were determined by solid-phase micro-extraction and referred to the reference compound 2,3-dimethylnaphthalene. The chemical oxygen demand (COD) and total organic carbon (TOC) values of the effluents were in the range of 30-2,850 mg L(-1) (COD) and 2-614 mg L(-1) (TOC). With respect to the metal concentrations, all samples were not heavily polluted. The

  20. Fracture toughness of A533B Part III - variability of A533B fracture toughness as determined from Charpy data

    International Nuclear Information System (INIS)

    Druce, S.G.; Eyre, B.L.

    1978-08-01

    This is the final part of a series of three reports examining the upper shelf fracture toughness of A533B Class 1 pressure vessel steel. Part I (AERE R 8968) critically reviews the current elasto plastic fracture mechanics methodologies employed to characterise toughness following extensive yielding and Part II (AERE R 8969) examines several sources of fracture mechanics data pertinent to A533B Class 1 in the longitudinal (RW) orientation. Part III is a review of the effects of (i) position and orientation within the plate (ii) welding processes and post weld heat treatment and (iii) neutron irradiation as measured by Charpy impact testing. It is concluded that the upper shelf factor energy is dependent on orientation and position and can be reduced by welding, extended post weld heat treatments and neutron irradiation. Neutron irradiation effects are known to be strongly dependent on composition and metallurgical conditions, but an explanation for the variability following extended post weld treatments has yet to be resolved. (author)

  1. 40 CFR Appendix B to Part 50 - Reference Method for the Determination of Suspended Particulate Matter in the Atmosphere (High...

    Science.gov (United States)

    2010-07-01

    ... analysis. Quality assurance procedures and guidance are provided in part 58, appendixes A and B, of this..., and shall be mounted so as to form an air inlet gap between the cover and the sampler housing walls...-600/9-76-005, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, 1976. 2. Quality...

  2. 41 CFR 105-74.500 - How are violations of this part determined for recipients other than individuals?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false How are violations of... Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL... DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Violations of this Part and Consequences § 105-74.500 How...

  3. 40 CFR Appendix E to Part 112 - Determination and Evaluation of Required Response Resources for Facility Response Plans

    Science.gov (United States)

    2010-07-01

    ... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS OIL POLLUTION PREVENTION Pt. 112, App. E Appendix E... boundary lines defined in 46 CFR part 7, except in the Gulf of Mexico. In the Gulf of Mexico, it means the... meet the requirements for arrival on-scene in accordance with section 5.3 of this appendix. An on-water...

  4. 40 CFR Appendix A to Part 503 - Procedure To Determine the Annual Whole Sludge Application Rate for a Sewage Sludge

    Science.gov (United States)

    2010-07-01

    ... Whole Sludge Application Rate for a Sewage Sludge A Appendix A to Part 503 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SEWAGE SLUDGE STANDARDS FOR THE USE OR DISPOSAL OF SEWAGE SLUDGE Pt... a Sewage Sludge Section 503.13(a)(4)(ii) requires that the product of the concentration for each...

  5. Maternal weight determines the association between Hbalc in second half of pregnancy and risk of large for gestational age babies

    DEFF Research Database (Denmark)

    Nielsen, Gunnar Lauge; Dethlefsen, Claus; Møller, Margrethe

    Aim: To assess the association between maternal glycosylated haemoglobin (HbA1c) in diabetic pregnancies and the risk of delivering large for gestational age babies (LGA) taking into account maternal body mass index (BMI), weight gain, age, White class, and smoking habits.  Method: We identified...... all pregnant diabetic women in a Danish county. HbA1c values after 20th gestational week were collected and offspring was categorized as large, normal or small for gestational age. Logistic regression models we fitted to assess the association between HbA1c and risk of delivering a LGA baby taking...... into account the impact of potential confounding from the above mentioned factors.   Results: We found 209 singleton pregnancies of which 59% (95% CI: 52%-65%) terminated with a LGA baby. HbA1c, BMI, and weight gain were all associated with increasing risk of delivering a LGA baby. Analyses stratified...

  6. 40 CFR Appendix B to Part 136 - Definition and Procedure for the Determination of the Method Detection Limit-Revision 1.11

    Science.gov (United States)

    2010-07-01

    ... calculated method detection limit. To insure that the estimate of the method detection limit is a good...) where: MDL = the method detection limit t(n-1,1- α=.99) = the students' t value appropriate for a 99... Determination of the Method Detection Limit-Revision 1.11 B Appendix B to Part 136 Protection of Environment...

  7. 40 CFR Appendix J to Part 50 - Reference Method for the Determination of Particulate Matter as PM10 in the Atmosphere

    Science.gov (United States)

    2010-07-01

    ... samplers. The user's goals in sampling determine the relative importance of various filter characteristics... shall have an associated operation or instruction manual as required by part 53 of this chapter which... manual and Reference 2 for specific guidance on calibration. Reference 14 provides additional information...

  8. Part I. Application of pulse polarography and pulse anodic stripping to the determination of selected heavy metals in natural waters. Part II. Application of controlled potential coulometric techniques to the determination of uranium

    International Nuclear Information System (INIS)

    Crosmun, S.T.

    1977-06-01

    The use of a thin mercury film wax-impregnated graphite electrode for the simultaneous determination of cadmium, lead and zinc in an acetate buffer by differential pulse anodic stripping voltammetry is described. Optimal instrumental parameters for maximum resolution and sensitivity for simultaneous analysis of these three elements in natural waters are discussed. The interference of copper with the determination of zinc is investigated in detail. An optimal mercury film thickness for this electrode is suggested. A method utilizing differential pulse polarography for the determination of chromium (VI) in natural water is described. Additions of 0.62 μg Cu(II) ml -1 and 0.55 μg Fe(III) ml -1 did not interfere with the determination of 0.050 μg Cr(VI) ml -1 . The natural water samples containing Cr(VI) were buffered to approximately pH 7 with 0.1 M ammonium acetate and 0.005 M ethylenediamine and analyzed. Natural water samples of chromium from 0.035 μg to 2.0 μg.ml -1 may be analyzed directly without further preparation. The detection limit is 0.010 μg.ml -1 . A novel, highly efficient cell with integral stirrer for controlled potential coulometry is described. This cell was used to demonstrate the feasibility of determining uranium (VI) by predictive coulometry. A PDP 8/I minicomputer was used to predict the coulometric endpoint with high accuracy within 2.5 minutes in a titration which normally takes about 10 minutes. This technique was shown to yield acceptable results even in the presence of an interfering phosphate matrix

  9. Thickness determination of large-area films of yttria-stabilized zirconia produced by pulsed laser deposition

    DEFF Research Database (Denmark)

    Pryds, N.; Christensen, Bo Toftmann; Bilde-Sørensen, Jørgen

    2006-01-01

    of the attenuation for various values of film thickness with the program CASINO. These results have been compared with direct measurements in the SEM of the film thickness on a cross-section on one of the wafers. The results of these measurements demonstrate the ability of this technique to accurately determine...

  10. Microscopic determination of leading terms of the interaction Hamiltonian between sd- and g-parts in the sdg IBM

    International Nuclear Information System (INIS)

    Zhang Zhanjun; Liu Yong; Sang Jianping

    1995-01-01

    Starting from one of the microscopic sdg interacting boson approximations, the leading terms in the interaction Hamiltonian are discussed by using numerical investigations. Comparisons of both the calculated levels and the overlap of wave functions between the exact results and the approximations are made to find out negligible part in the Hamiltonian. The results show that the leading terms given may provide a way to simplify the complex calculations

  11. Determination of the detection limit and decision threshold for ionizing radiation measurements. Part 2: Fundamentals and application to counting measurements with the influence of sample treatment

    International Nuclear Information System (INIS)

    2000-01-01

    This part of ISO 11929 addresses the field of ionizing radiation measurements in which events (in particular pulses) on samples are counted after treating them (e.g. aliquotation, solution, enrichment, separation). It considers, besides the random character of radioactive decay and of pulse counting, all other influences arising from sample treatment, (e.g. weighing, enrichment, calibration or the instability of the test setup). ISO 11929 consists of the following parts, under the general title Determination of the detection limit and decision threshold for ionizing radiation measurements: Part 1: Fundamentals and application to counting measurements without the influence of sample treatment; Part 2: Fundamentals and application to counting measurements with the influence of sample treatment; Part 3: Fundamentals and application to counting measurements by high resolution gamma spectrometry, without the influence of sample treatment; Part 4: Fundamentals and application to measurements by use of linear scale analogue ratemeters, without the influence of sample treatment. This part of ISO 11929 was prepared in parallel with other International Standards prepared by WG 2 (now WG 17): ISO 11932:1996, Activity measurements of solid materials considered for recycling, re-use or disposal as non radioactive waste, and ISO 11929-1, ISO 11929-3 and ISO 11929-4 and is, consequently, complementary to these documents

  12. Method for Determination of Neptunium in Large-Sized Urine Samples Using Manganese Dioxide Coprecipitation and 242Pu as Yield Tracer

    DEFF Research Database (Denmark)

    Qiao, Jixin; Hou, Xiaolin; Roos, Per

    2013-01-01

    A novel method for bioassay of large volumes of human urine samples using manganese dioxide coprecipitation for preconcentration was developed for rapid determination of 237Np. 242Pu was utilized as a nonisotopic tracer to monitor the chemical yield of 237Np. A sequential injection extraction chr...... and rapid analysis of neptunium contamination level for emergency preparedness....

  13. Analysis of Large Seeds from Three Different Medicago truncatula Ecotypes Reveals a Potential Role of Hormonal Balance in Final Size Determination of Legume Grains

    Directory of Open Access Journals (Sweden)

    Kaustav Bandyopadhyay

    2016-09-01

    Full Text Available Legume seeds are important as protein and oil source for human diet. Understanding how their final seed size is determined is crucial to improve crop yield. In this study, we analyzed seed development of three accessions of the model legume, Medicago truncatula, displaying contrasted seed size. By comparing two large seed accessions to the reference accession A17, we described mechanisms associated with large seed size determination and potential factors modulating the final seed size. We observed that early events during embryogenesis had a major impact on final seed size and a delayed heart stage embryo development resulted to large seeds. We also observed that the difference in seed growth rate was mainly due to a difference in embryo cell number, implicating a role of cell division rate. Large seed accessions could be explained by an extended period of cell division due to a longer embryogenesis phase. According to our observations and recent reports, we observed that auxin (IAA and abscisic acid (ABA ratio could be a key determinant of cell division regulation at the end of embryogenesis. Overall, our study highlights that timing of events occurring during early seed development play decisive role for final seed size determination.

  14. Determining

    Directory of Open Access Journals (Sweden)

    Bahram Andarzian

    2015-06-01

    Full Text Available Wheat production in the south of Khuzestan, Iran is constrained by heat stress for late sowing dates. For optimization of yield, sowing at the appropriate time to fit the cultivar maturity length and growing season is critical. Crop models could be used to determine optimum sowing window for a locality. The objectives of this study were to evaluate the Cropping System Model (CSM-CERES-Wheat for its ability to simulate growth, development, grain yield of wheat in the tropical regions of Iran, and to study the impact of different sowing dates on wheat performance. The genetic coefficients of cultivar Chamran were calibrated for the CSM-CERES-Wheat model and crop model performance was evaluated with experimental data. Wheat cultivar Chamran was sown on different dates, ranging from 5 November to 9 January during 5 years of field experiments that were conducted in the Khuzestan province, Iran, under full and deficit irrigation conditions. The model was run for 8 sowing dates starting on 25 October and repeated every 10 days until 5 January using long-term historical weather data from the Ahvaz, Behbehan, Dezful and Izeh locations. The seasonal analysis program of DSSAT was used to determine the optimum sowing window for different locations as well. Evaluation with the experimental data showed that performance of the model was reasonable as indicated by fairly accurate simulation of crop phenology, biomass accumulation and grain yield against measured data. The normalized RMSE were 3%, 2%, 11.8%, and 3.4% for anthesis date, maturity date, grain yield and biomass, respectively. Optimum sowing window was different among locations. It was opened and closed on 5 November and 5 December for Ahvaz; 5 November and 15 December for Behbehan and Dezful;and 1 November and 15 December for Izeh, respectively. CERES-Wheat model could be used as a tool to evaluate the effect of sowing date on wheat performance in Khuzestan conditions. Further model evaluations

  15. A large neutron missing mass spectrometer using long plastic scintillators with electronical determination of the neutron interaction point

    International Nuclear Information System (INIS)

    Apel, W.D.; Mueller, H.; Schinzel, D.; Sigurdsson, G.; Staudenmaier, H.M.; Stier, U.

    1975-11-01

    A large acceptance and high efficiency neutron detector is described. The sensitive area and volume of the detector is 3.07 m 2 and 1.03 m 3 respectively. The detector consists of sixteen elements of plastic scintillator, each having the dimensions (16 x 16 x 240) cm 3 . The mean detection efficiency is about 33% for neutrons of 100-500 MeV/c momentum. An interesting feature of this instrument is the accuracy achieved in locating incident particles, which is +-3 cm for charged particles and +-4 cm for neutrons. The accuracy achieved for the time-of-flight measurement is +-1 nsec for fast neutrons. (orig.) [de

  16. The XChemExplorer graphical workflow tool for routine or large-scale protein–ligand structure determination

    Science.gov (United States)

    Krojer, Tobias; Talon, Romain; Pearce, Nicholas; Douangamath, Alice; Brandao-Neto, Jose; Dias, Alexandre; Marsden, Brian

    2017-01-01

    XChemExplorer (XCE) is a data-management and workflow tool to support large-scale simultaneous analysis of protein–ligand complexes during structure-based ligand discovery (SBLD). The user interfaces of established crystallo­graphic software packages such as CCP4 [Winn et al. (2011 ▸), Acta Cryst. D67, 235–242] or PHENIX [Adams et al. (2010 ▸), Acta Cryst. D66, 213–221] have entrenched the paradigm that a ‘project’ is concerned with solving one structure. This does not hold for SBLD, where many almost identical structures need to be solved and analysed quickly in one batch of work. Functionality to track progress and annotate structures is essential. XCE provides an intuitive graphical user interface which guides the user from data processing, initial map calculation, ligand identification and refinement up until data dissemination. It provides multiple entry points depending on the need of each project, enables batch processing of multiple data sets and records metadata, progress and annotations in an SQLite database. XCE is freely available and works on any Linux and Mac OS X system, and the only dependency is to have the latest version of CCP4 installed. The design and usage of this tool are described here, and its usefulness is demonstrated in the context of fragment-screening campaigns at the Diamond Light Source. It is routinely used to analyse projects comprising 1000 data sets or more, and therefore scales well to even very large ligand-design projects. PMID:28291762

  17. The XChemExplorer graphical workflow tool for routine or large-scale protein-ligand structure determination.

    Science.gov (United States)

    Krojer, Tobias; Talon, Romain; Pearce, Nicholas; Collins, Patrick; Douangamath, Alice; Brandao-Neto, Jose; Dias, Alexandre; Marsden, Brian; von Delft, Frank

    2017-03-01

    XChemExplorer (XCE) is a data-management and workflow tool to support large-scale simultaneous analysis of protein-ligand complexes during structure-based ligand discovery (SBLD). The user interfaces of established crystallographic software packages such as CCP4 [Winn et al. (2011), Acta Cryst. D67, 235-242] or PHENIX [Adams et al. (2010), Acta Cryst. D66, 213-221] have entrenched the paradigm that a `project' is concerned with solving one structure. This does not hold for SBLD, where many almost identical structures need to be solved and analysed quickly in one batch of work. Functionality to track progress and annotate structures is essential. XCE provides an intuitive graphical user interface which guides the user from data processing, initial map calculation, ligand identification and refinement up until data dissemination. It provides multiple entry points depending on the need of each project, enables batch processing of multiple data sets and records metadata, progress and annotations in an SQLite database. XCE is freely available and works on any Linux and Mac OS X system, and the only dependency is to have the latest version of CCP4 installed. The design and usage of this tool are described here, and its usefulness is demonstrated in the context of fragment-screening campaigns at the Diamond Light Source. It is routinely used to analyse projects comprising 1000 data sets or more, and therefore scales well to even very large ligand-design projects.

  18. Chromatographic lipophilicity determination using large volume injections of the solvents non-miscible with the mobile phase.

    Science.gov (United States)

    Sârbu, Costel; Naşcu-Briciu, Rodica Domnica; Casoni, Dorina; Kot-Wasik, Agata; Wasik, Andrzej; Namieśnik, Jacek

    2012-11-30

    A new perspective in the lipophilicity evaluation through RP-HPLC is permitted by analysis of the retention factor (k) obtained by injecting large volumes of test samples prepared in solvents immiscible with mobile phase. The experiment is carried out on representative groups of compounds with increased toxicity (mycotoxins and alkaloids) and amines with important biological activity (naturally occurring monoamine compounds and related drugs), which are covering a large interval of lipophilicity. The stock solution of each compound was prepared in hexane and the used mobile phases were mixtures of methanol or acetonitrile and water, in suited volume ratio. The injected volume was between 10 and 100 μL, while the used stationary phases were RP-18 and RP-8. On both reverse stationary phases the retention factors were linearly decreasing while the injection volume was increasing. In all cases, the linear models were highly statistically significant. On the basis of the obtained results new lipophilicity indices were purposed and discussed. The developed lipophilicity indices and the computationally expressed ones are correlated at a high level of statistical significance. Copyright © 2012 Elsevier B.V. All rights reserved.

  19. Determination of the fine structure in the ionization plots obtained from a mass spectrometer with a large energy dispersion

    International Nuclear Information System (INIS)

    Deruaz, Daniel.

    1974-01-01

    The precise determination of ionization potentials, fragment ion appearance potentials and different excited state levels of the positive ions formed, together with phenomena due to an electron impact, were studied from ionization efficiency curves obtained by mass spectrometry. A standard ion source and an analytical method of electron energy dispersion reduction were used to study fine structures of ionization efficiency curves. Since the mass spectrometer was not adapted for the acquisition of ionization efficiency curve data an electronic system was designed to record these curves automatically. A precise stepwise potential variation of 45+-0.04mV was obtained, and for each step an intensity proportional to the number of ions created by the fragment considered, the additional gain being 4.4 and the linearity greater than 1% over a 13-volt region. Before each set of measurements the scattering was determined by calculation of the second derivative of a logistic function deduced from the cubic regression of the experimental helium function ionization efficiency curve values. The precision, given by the variance analysis SNEDECOR F test, is higher than 1/1000. For each series of recordings the numerical values were processed by a computer to raise by twenty the signal to noise ratio and calculate the ionization efficiency curve values by the energy difference method and the iterative unfolding method. In this way a high sensitivity was obtained for the determination of the curves near the ionization threshold, and a precision below 50MeV (at least equivalent to that given by ionization cells with quasi-monoenergetic electron beams) for the values of the ionization potentials, the appearance potentials and the excited state energy levels. In order to judge the reliability of the technique the ionization potentials of a set of eleven complex molecules were determined and compared with the results obtained by photoionization and photoelectron spectrometry [fr

  20. Determination of inorganic compounds in drinking water on the basis of house water heater scale, part 1: Determination of heavy metals and uranium

    Directory of Open Access Journals (Sweden)

    Rajković Miloš B.

    2004-01-01

    Full Text Available The analysis of scale originated from drinking water on the house water heater, showed that scale is basically calcium carbonate that crystallizes hexagonally in the form of calcite. Scale taken as a sample from different spots in Belgrade – upper town of Zemun (sample 1 and Pančevo (sample 2 showed different configuration although it came from the same waterworks. That indicates either that the water flowing through waterworks pipes in different parts of the city is not the same or the waterworks net is not the same (age, maintaining, etc. All the elements which are dominant in drinking water (Ca, Mg, K, and Na, and which could be found in water by natural processes, are by their content far below the values regulated by law. The analysis also showed the presence of many metals: Ti, Pb, Zn, Cu Li, Sr, Cd, and Cr in the first sample, which are not found in the scale taken near Pančevo. The results obtained by calculating the mass concentration in drinking water on the basis of scale content, showed that both waters belonged to the category of low mineral waters. Contents of inorganic substances in these waters (117.85 mg/dm3 for sample 1 or 80.83 mg/dm3 for sample 2 are twice lower than the values predicted by the legislation. Gammaspectrometric analysis indicates the presence of radioactive elements – uranium and strontium which can influence human health.

  1. The Determination of "Apparent" pKa's. Part II: An Experiment Using Very Weak Acids (pKa's > 11.4).

    Science.gov (United States)

    Cawley, John J.

    1995-01-01

    Presents an experiment designed to show students that the Henderson-Hasselbalch equation will fail when they use this particular one-half titration technique for acids with large pKa's. Involves determining the apparent pKa for such acids and using that to calculate the true pKa. (JRH)

  2. Determination of AC Characteristics of Superconducting Dipole Magnets in the Large Hadron Collider Based on Experimental Results and Simulations

    CERN Document Server

    Ambjørndalen, Sara; Verweij, Arjan

    The Large Hadron Collider (LHC) utilizes high-field superconducting Main Dipole Magnets that bend the trajectory of the beam. The LHC ring is electrically divided into eight octants, each allocating a 7 km chain of 154 Main Dipole Magnets. Dedicated de- tection and protection systems prevent irreversible magnet damage caused by quenches. Quench is a local transition from the superconducting to the normal conducting state. Triggering of such systems, along with other failure scenarios, result in fast transient phenomena. In order to analyze the consequence of such electrical transients and failures in the dipole chain, one needs a circuit model that is validated against measurements. Currently, there exists an equivalent circuit of the Main Dipole Magnet resolved at an aperture level. Each aperture model takes into account the dynamic effects occurring in the magnets, trough a lossy-inductance model and parasitic capacitances to ground. At low frequencies the Main Dipole Magnet behaves as a linear inductor. Ca...

  3. Characterization of airborne particulate matter in Santiago, Chile. Part 5: non-destructive determination by x-ray fluorescence

    International Nuclear Information System (INIS)

    Poblete, V.H.; Hurtado, O.; Toro, P.

    1995-01-01

    A procedure for non-destructive analysis of airborne particular matter using X ray fluorescence is presented. The elements Fe, Pb and Zn were determined and their concentration compared with the results reported by other techniques. The homogeneity of the distribution of Fe in the samples was investigated. (author). 4 refs, 5 figs

  4. 15 CFR Supplement No. 2 to Part 766 - Guidance on Charging and Penalty Determinations in Settlement of Administrative Enforcement Cases...

    Science.gov (United States)

    2010-01-01

    ... suspended on the basis of adverse economic consequences only if it is found that future violations of the... (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION REGULATIONS... as the “antiboycott provisions”). It also describes how BIS makes penalty determinations in the...

  5. Determination of Energy of a Clinical Electron Beam as Part of a Routine Quality Assurance and Audit System

    Science.gov (United States)

    Hernández-Bello, Jimmy; D'Souza, Derek; Rossenberg, Ivan

    2002-08-01

    A method to determine the electron beam energy and an electron audit based on the current IPEM electron Code of Practice has been devised. During the commissioning on the new Varian 2100CD linear accelerator in The Middlesex Hospital, two methods were devised for the determination of electron energy. The first method involves the use of a two-depth method, whereby the ratio of ionisation (presented as a percentage) measured by an ion chamber at two depths in solid water is used to compare against the baseline ionisation depth value for that energy. The second method involves the irradiation of an X-ray film in solid water to obtain a depth dose curve and, hence determine the half value depth and practical range of the electrons. The results showed that the two-depth method has a better accuracy, repeatability, reliability and consistency than the X-ray method. The results for the electron audit showed that electron absolute outputs are obtained from ionisation measurements in solid water, where the energy-range parameters such as practical range and the depth at which ionisation is 50% of that at the maximum for the depth-ionisation curve are determined.

  6. Theoretical analysis of nuclear reactors (Phase I), I-V, Part V, Determining the fine flux distribution

    International Nuclear Information System (INIS)

    Pop-Jordanov, J.

    1962-07-01

    Mono energetic neutron transport equation was solved by Carlson numerical method in cylindrical geometry. S n code was developed for the digital computer ZUSE Z23. Neutron flux distribution was determined for the RA reactor cell by applying S 4 approximation. Reactor cell was treated as D 2 O-U-D 2 O system. Time of iteration was 185 s [sr

  7. 76 FR 60867 - Certain Electronic Imaging Devices; Notice of Commission Determination To Review-in-Part a Final...

    Science.gov (United States)

    2011-09-30

    ... asserted patents under the doctrines of implied license and exhaustion. The Commission has also determined... ``saving an indication of the first orientation to memory.'' See ID at 27. Assume that the EVO 4G... ``sav[e] an indication'' of the ``first orientation'' to memory? Specifically, does the EVO 4G save an...

  8. Determining the axial power profile of partly flooded fuel in a compact core assembled in reactor LR-0

    International Nuclear Information System (INIS)

    Košťál, Michal; Švadlenková, Marie; Baroň, Petr; Rypar, Vojtěch; Milčák, Ján

    2016-01-01

    Highlights: • Fission density in partly flooded compact core. • Calculation of fission density axial profile. • Significant calculational under prediction of experimental axial profile. - Abstract: Measurement and calculation of the axial power profile near the boundary of a moderated and non-moderated core is used to analyze the suitability of the neutron-physical process description, mainly the angular cross-section of a water-moderated uranium system. This is also an important issue because it affects the radiation situation above the partly flooded core of a water-moderated reactor. Axial power profiles of various fuel pins irradiated on reactor LR-0 were measured and the results were compared with MCNP6 code calculations using the ENDF/B-VII.0 nuclear data library. The calculated power profile in positions above the moderator level significantly underestimates experimental results. This might be caused by an improper description of the angular distribution of scattered neutrons in a water-moderated uranium system.

  9. Determination of environmental levels of 239240Pu, 241Am, 137Cs, and 90Sr in large volume sea water samples

    International Nuclear Information System (INIS)

    Sutton, D.C.; Calderon, G.; Rosa, W.

    1976-06-01

    A method is reported for the determination of environmental levels of 239 240 Pu and 241 Am in approximately 60-liter size samples of seawater. 137 Cs and 90 Sr were also separated and determined from the same samples. The samples were collected at the sea surface and at various depths in the oceans through the facilities of the Woods Hole Oceanographic Institution. Plutonium and americium were separated from the seawater by iron hydroxide scavenging then treated with a mixture of nitric, hydrochloric, and perchloric acids. A series of anion exchange separations were used to remove interferences and purify plutonium and americium; then each was electroplated on platinum disks and measured by solid state alpha particle spectrometry. The overall chemical yields averaged 62 +- 9 and 69 +- 14 percent for 236 Pu, and 243 Am tracers, respectively. Following the iron hydroxide scavenge of the transuranics, cesium was removed from the acidified seawater matrix by adsorption onto ammonium phosphomolybdate. Cesium carrier and 137 Cs isolation was effected by ion exchange and precipitations were made using chloroplatinic acid. The samples were weighed to determine overall chemical yield then beta counted. Cesium recoveries averaged 75 +- 5 percent. After cesium was removed from the seawater matrix, the samples were neutralized with sodium hydroxide and ammonium carbonate was added to precipitate 85 Sr tracer and the mixed alkaline earth carbonates. Strontium was separated as the nitrate and scavenged by chromate and hydroxide precipitations. Yttrium-90 was allowed to build up for two weeks, then milked and precipitated as the oxalate, weighed, and beta counted. The overall chemical yields of 85 Sr tracer averaged 84 +- 16 percent. The recovery of the yttrium oxalate precipitates averaged 96 +- 3 percent

  10. Nuclear fuel technology - Tank calibration and volume determination for nuclear materials accountancy - Part 6: Accurate in-tank determination of liquid density in accountancy tanks equipped with dip tubes

    International Nuclear Information System (INIS)

    2008-01-01

    ISO 18213 deals with the acquisition, standardization, analysis, and use of calibration data to determine liquid volumes in process tanks for accountability purposes. This part of ISO 18213 is complementary to the other parts, ISO 18213-1 (procedural overview), ISO 18213-2 (data standardization), ISO 18213-3 (statistical methods), ISO 18213-4 (slow bubbling rate), ISO 18213-5 (fast bubbling rate). The procedure described in this part of ISO 18213 is a two-step procedure. First, a liquid of known density is used to determine the vertical distance between the tips of the two probes (i.e. to calibrate their separation). The calibration step requires synchronous (or as nearly synchronous as possible) measurements of the pressure exerted at the tips of two probes by the calibration liquid in which they are submerged. The measurements obtained are used to make an accurate determination of probe separation. Second, the unknown density of the process liquid is determined with the aid of the probe separation calibration. The density-determination step also requires (nearly) synchronous measurements of the pressure exerted at the tips of two probes by the process liquid of unknown density. With careful technique, it is possible to make determinations of liquid density with in-tank measurements that approach the accuracy and precision of those made in the laboratory. Moreover, density determinations made with in-tank measurements are automatically made at the observed temperature of the tank liquid. Thus, no additional information about the liquid is required to infer its density at its tank temperature from determinations of its density at some other temperature. Except that the density of the process liquid is generally not well characterized, the steps involved in determining the height of process liquid in the tank are the same as those for determining the height of calibration liquid. Thus, the method of density determination given in this part of ISO 18213 is very

  11. Seasonal Differences in Determinants of Time Location Patterns in an Urban Population: A Large Population-Based Study in Korea.

    Science.gov (United States)

    Lee, Sewon; Lee, Kiyoung

    2017-06-22

    Time location patterns are a significant factor for exposure assessment models of air pollutants. Factors associated with time location patterns in urban populations are typically due to high air pollution levels in urban areas. The objective of this study was to determine the seasonal differences in time location patterns in two urban cities. A Time Use Survey of Korean Statistics (KOSTAT) was conducted in the summer, fall, and winter of 2014. Time location data from Seoul and Busan were collected, together with demographic information obtained by diaries and questionnaires. Determinants of the time spent at each location were analyzed by multiple linear regression and the stepwise method. Seoul and Busan participants had similar time location profiles over the three seasons. The time spent at own home, other locations, workplace/school and during walk were similar over the three seasons in both the Seoul and Busan participants. The most significant time location pattern factors were employment status, age, gender, monthly income, and spouse. Season affected the time spent at the workplace/school and other locations in the Seoul participants, but not in the Busan participants. The seasons affected each time location pattern of the urban population slightly differently, but overall there were few differences.

  12. Modeling, estimation and identification methods for static shape determination of flexible structures. [for large space structure design

    Science.gov (United States)

    Rodriguez, G.; Scheid, R. E., Jr.

    1986-01-01

    This paper outlines methods for modeling, identification and estimation for static determination of flexible structures. The shape estimation schemes are based on structural models specified by (possibly interconnected) elliptic partial differential equations. The identification techniques provide approximate knowledge of parameters in elliptic systems. The techniques are based on the method of maximum-likelihood that finds parameter values such that the likelihood functional associated with the system model is maximized. The estimation methods are obtained by means of a function-space approach that seeks to obtain the conditional mean of the state given the data and a white noise characterization of model errors. The solutions are obtained in a batch-processing mode in which all the data is processed simultaneously. After methods for computing the optimal estimates are developed, an analysis of the second-order statistics of the estimates and of the related estimation error is conducted. In addition to outlining the above theoretical results, the paper presents typical flexible structure simulations illustrating performance of the shape determination methods.

  13. Seasonal Differences in Determinants of Time Location Patterns in an Urban Population: A Large Population-Based Study in Korea

    Directory of Open Access Journals (Sweden)

    Sewon Lee

    2017-06-01

    Full Text Available Time location patterns are a significant factor for exposure assessment models of air pollutants. Factors associated with time location patterns in urban populations are typically due to high air pollution levels in urban areas. The objective of this study was to determine the seasonal differences in time location patterns in two urban cities. A Time Use Survey of Korean Statistics (KOSTAT was conducted in the summer, fall, and winter of 2014. Time location data from Seoul and Busan were collected, together with demographic information obtained by diaries and questionnaires. Determinants of the time spent at each location were analyzed by multiple linear regression and the stepwise method. Seoul and Busan participants had similar time location profiles over the three seasons. The time spent at own home, other locations, workplace/school and during walk were similar over the three seasons in both the Seoul and Busan participants. The most significant time location pattern factors were employment status, age, gender, monthly income, and spouse. Season affected the time spent at the workplace/school and other locations in the Seoul participants, but not in the Busan participants. The seasons affected each time location pattern of the urban population slightly differently, but overall there were few differences.

  14. Influence of the reagent concentration of the colorimetric copper determination with sodium diethyl dithiocarbamate (abbreviated: D.D.C.) and its importance for the determination of copper in the presence of large amounts of iron

    NARCIS (Netherlands)

    Karsten, P.; Rademaker, S.C.; Walraven, J.J.

    1950-01-01

    From a research about the influence of the reagent concentration on the copper determination with sodium di-ethyl-di-thio-carbamate in the presence of large amounts of iron some insight was gained into factors which had never been examined so far and which were found to have great influence on the

  15. Model for impedance determinations and power deposition characterization in three-electrode configurations for capacitive radio frequency hyperthermia. Part A: impedance determinations

    International Nuclear Information System (INIS)

    Morand, A.; Bolomey, J.C.

    1987-01-01

    By means of simplifying assumptions, a 2-D rectangular model for three-electrode radio frequency hyperthermia systems is established. The validity of these assumptions is discussed. The electric behavior of the model is characterized by a three-port equivalent network. The three resistances in the network are determined by means of conformal mappings. The process is applied to devices exhibiting a plane of symmetry but provisions exist for a generalization to asymmetrical systems. The set of five design elements completing the description of the system comprises a resistance and a balance factor as the two electrical parameters, and electrode sizes and spacings as the three geometrical parameters. For practical purposes the links between these parameters, figured out by computations, are mapped into block diagrams and into a chart. The block diagrams show that the electrode sizes and spacings have almost uncorrelated effects upon the electrical parameters. When the values of any three among the five parameters have been chosen, the chart gives the two unknown parameter values by direct reading or through interpolations. The use of complementary systems widens the chart range to almost any practical system values, and it allows the two-electrode system relations between resistance and capacitance to be generalized to any three-electrode system

  16. Transfer Matrix Method for the Determination of the Natural Vibration Characteristics of Realistic Thrusting Launch Vehicle—Part I

    Directory of Open Access Journals (Sweden)

    Laith K. Abbas

    2013-01-01

    Full Text Available The feasibility of using the transfer matrix method (TMM to compute the natural vibration characteristics of a flexible rocket/satellite launch vehicle is explored theoretically. In the approach to the problem, a nonuniform free-free Timoshenko and Euler-Bernoulli beamlike structure is modeled. A provision is made to take into consideration the effects of shear deformation and rotary inertia. Large thrust-to-weight ratio leads to large axial accelerations that result in an axial inertia load distribution from nose to tail which causes the development of significant compressive forces along the length of the launch vehicle. Therefore, it is important to take into account this effect in the transverse vibration model. Once the transfer matrix of a single component has been obtained, the product of all component matrices composes the matrix of the entire structure. The frequency equation and mode shape are formulated in terms of the elements of the structural matrices. Flight test and analytical results validate the present TMM formulas.

  17. Goitre in girls at the age of puberty. Part 2. Determination of thyroid iodine uptake and triiodothyronine-binding index

    International Nuclear Information System (INIS)

    Mach, W.

    1977-01-01

    Thyroid iodine uptake and 125 I-triiodothyronine-binding index (T 3 BC) were determined in 114 girls with juvenile goitre and the results were related to the size of the goitre and its duration. Measurements of thyroid iodine uptake showed a gradual decrease of its value with increasing size of goitre and its longer duration without reaching, however, the values regarded as normal. T 3 BC showed no significant changes in relation to the size of goitre and its duration. (author)

  18. [Studies on the industrial styrene poisoning (Part X). Determination of styrene in biological materials by gas chromatography (author's transl)].

    Science.gov (United States)

    Teramoto, K; Horiguchi, S

    1980-09-01

    For monitoring solvents exposure, it is useful to determine not only metabolites of the solvents in urine but also the solvents themselves in blood and tissues. In a series of studies on the industrial styrene poisoning, we have been determining styrene in blood and other tissues as occasion calls. Our examination of the method is presented in this report. The outline on the method is as follows: Aliquots of 0.5g of tissues being added 5 ml of n-hexane are homogenized by a high-speed homogenizer (Polytoron) for 10 to 30 seconds and the filtrates containing extracts are analyzed for styrene by gas chromatography. The linearity was ascertained from the calibration curve obtained by adding the known quantities of styrene (4, 10, 20, 40, 100 ppm) to the blood, liver and adipose tissues of rats. Rates of recoveries of styrene from the above tissues were 92 to 101 per cent. Reproducibility of this method was examined by repeating determinations of styrene in the blood, liver and adipose tissues of rats exposed to 500 ppm styrene for 4 hours, the coefficients of variation being 2.8 to 14.0 per cent. There was an approximately linear relationship between the styrene concentration (0 to 1,000 ppm) of the exposed air and those in the blood of exposed rats. We conclude that our simple and rapid method is applicable to determination of solvents other than styrene in organs and tissues by combining suitable solvents for extraction and packings of gas chromatography.

  19. Quantitative asteroseismology: Determination of the core composition and layering of the ZZ Ceti star R548. Part I

    Directory of Open Access Journals (Sweden)

    Fontaine G.

    2013-03-01

    Full Text Available We present a detailed asteroseismological study of the pulsating white dwarf R548 based on fits to newly detected periods and the use of the forward method. In this first part, we concentrate on the frequency extraction analysis. Based on an unexploited CFHT/LAPOUNE broadband photometric campaign of high S/N, we are able to obtain a finer frequency spectrum and uncover two triplets, two doublets, and two singlets. The low-amplitude and “simple” pulsator R548 is an ideal candidate for carrying on a complete asteroseismological analysis within the framework of the adiabatic approximation to obtain optimized structural parameters, including the envelope layering and the bulk composition of the core.

  20. Application of the 137Cs determination to evaluate the erosion rates in cultivated soils in the west part of Cuba

    International Nuclear Information System (INIS)

    Gil Castillo, Reinaldo; Peralta Vital, Jose Luis; Carrazana Gonzalez, Jorge; Riverol Rosquet, Mario; Penna Valenti, Fermin; Cabrera Calcedo, Eduardo

    2004-01-01

    The paper shows the experience in the application of 137Cs technique to estimate the erosion rates in cultivated soils (Ultisol) in the west part of the country, and the validation of the technique results by comparison against the results from traditional methods (watershed segments). The proportional, the simplified balance of mass and the balance of mass models were used to calculate the erosion rates, for three segments. In the evaluated area, have been obtained erosion rates from 3.5 to 7.1 t/ha/y for the segment I, from 5.17 to 10.3 t/ha/y for the segment III and from 2.3 to 17 t/ha/y for the segment IX. The conclusions are, the 137Cs technique is reliable for the estimation of erosion rates in the evaluated soil and the mass balance model obtained the nearest values to the estimated by watershed segments

  1. Iron Quadrangle, Brazil. Elemental concentration determined by k0-instrumental neutron activation analysis. Part 1. Soil samples

    International Nuclear Information System (INIS)

    Menezes, M.A.B.C.; Palmieri, H.E.L.; Leonel, L.V.; Nalini, H.A.Jr.; Jacimovic, R.

    2006-01-01

    The Iron Quadrangle, Minas Gerais, Brazil, is rich in mineral occurrences and is considered one of the richest mineral-bearing regions in the world. Most investigations in this region have dealt with the determination of arsenic and mercury but so far few studies have been carried out aiming at determining other important elements. Having in mind the potential risk caused by mineral activities, this study was developed in order to assess the potential influence of the soil on foodstuffs. The soil samples were collected from three sites inside and outside the Iron Quadrangle. The samples were analyzed at the Laboratory for Neutron Activation Analysis, CDTN/CNEN by the k 0 -instrumental neutron activation analysis. This paper reports the elemental concentration determined in soil and emphasises the elements cited in the Brazilian environmental legislation for soil. This work also confirms the high elemental concentration of several minerals, however, it is difficult to distinguish the contamination from anthropogenic activities from the natural occurrence. (author)

  2. Social Inequalities on Selected Determinants of Active Aging and Health Status Indicators in a Large Brazilian City (2003-2010).

    Science.gov (United States)

    Braga, Luciana de Souza; Lima-Costa, Maria Fernanda; César, Cibele Comini; Macinko, James

    2016-02-01

    To assess trends in social inequalities among 2,624 elderly living in Belo Horizonte, Brazil, in three domains of the World Health Organization's Active Aging model (physical environment, social determinants, use of health services) and health status indicators. Data came from two representative household surveys conducted in 2003 and 2010. Social inequality was measured by the slope and the relative index of inequality. Educational level was used to define socioeconomic status. Significant improvements were observed in the prevalence rates of 7 out of 12 indicators. However, the social inequalities persisted through 10 out of 12 selected active aging and health status indicators, except for fear of falling on the sidewalks/crossing the streets and fear of being robbed. Social inequalities persistence might be assigned to the continuity of unequal distribution of resources among groups with different educational levels. © The Author(s) 2015.

  3. Determinants of bone mass and bone size in a large cohort of physically active young adult men

    Directory of Open Access Journals (Sweden)

    Garrett P

    2006-02-01

    Full Text Available Abstract The determinants of bone mineral density (BMD at multiple sites were examined in a fit college population. Subjects were 755 males (mean age = 18.7 years entering the United States Military Academy. A questionnaire assessed exercise frequency and milk, caffeine, and alcohol consumption and tobacco use. Academy staff measured height, weight, and fitness. Calcaneal BMD was measured by peripheral dual-energy x-ray absorptiometry (pDXA. Peripheral-quantitative computed tomography (pQCT was used to measure tibial mineral content, circumference and cortical thickness. Spine and hip BMD were measured by DXA in a subset (n = 159. Mean BMD at all sites was approximately one standard deviation above young normal (p

  4. Solid-Phase Extraction and Large-Volume Sample Stacking-Capillary Electrophoresis for Determination of Tetracycline Residues in Milk

    Directory of Open Access Journals (Sweden)

    Gabriela Islas

    2018-01-01

    Full Text Available Solid-phase extraction in combination with large-volume sample stacking-capillary electrophoresis (SPE-LVSS-CE was applied to measure chlortetracycline, doxycycline, oxytetracycline, and tetracycline in milk samples. Under optimal conditions, the proposed method had a linear range of 29 to 200 µg·L−1, with limits of detection ranging from 18.6 to 23.8 µg·L−1 with inter- and intraday repeatabilities < 10% (as a relative standard deviation in all cases. The enrichment factors obtained were from 50.33 to 70.85 for all the TCs compared with a conventional capillary zone electrophoresis (CZE. This method is adequate to analyze tetracyclines below the most restrictive established maximum residue limits. The proposed method was employed in the analysis of 15 milk samples from different brands. Two of the tested samples were positive for the presence of oxytetracycline with concentrations of 95 and 126 µg·L−1. SPE-LVSS-CE is a robust, easy, and efficient strategy for online preconcentration of tetracycline residues in complex matrices.

  5. Large-scale determination of sequence, structure, and function relationships in cytosolic glutathione transferases across the biosphere.

    Science.gov (United States)

    Mashiyama, Susan T; Malabanan, M Merced; Akiva, Eyal; Bhosle, Rahul; Branch, Megan C; Hillerich, Brandan; Jagessar, Kevin; Kim, Jungwook; Patskovsky, Yury; Seidel, Ronald D; Stead, Mark; Toro, Rafael; Vetting, Matthew W; Almo, Steven C; Armstrong, Richard N; Babbitt, Patricia C

    2014-04-01

    The cytosolic glutathione transferase (cytGST) superfamily comprises more than 13,000 nonredundant sequences found throughout the biosphere. Their key roles in metabolism and defense against oxidative damage have led to thousands of studies over several decades. Despite this attention, little is known about the physiological reactions they catalyze and most of the substrates used to assay cytGSTs are synthetic compounds. A deeper understanding of relationships across the superfamily could provide new clues about their functions. To establish a foundation for expanded classification of cytGSTs, we generated similarity-based subgroupings for the entire superfamily. Using the resulting sequence similarity networks, we chose targets that broadly covered unknown functions and report here experimental results confirming GST-like activity for 82 of them, along with 37 new 3D structures determined for 27 targets. These new data, along with experimentally known GST reactions and structures reported in the literature, were painted onto the networks to generate a global view of their sequence-structure-function relationships. The results show how proteins of both known and unknown function relate to each other across the entire superfamily and reveal that the great majority of cytGSTs have not been experimentally characterized or annotated by canonical class. A mapping of taxonomic classes across the superfamily indicates that many taxa are represented in each subgroup and highlights challenges for classification of superfamily sequences into functionally relevant classes. Experimental determination of disulfide bond reductase activity in many diverse subgroups illustrate a theme common for many reaction types. Finally, sequence comparison between an enzyme that catalyzes a reductive dechlorination reaction relevant to bioremediation efforts with some of its closest homologs reveals differences among them likely to be associated with evolution of this unusual reaction

  6. Large-scale determination of sequence, structure, and function relationships in cytosolic glutathione transferases across the biosphere.

    Directory of Open Access Journals (Sweden)

    Susan T Mashiyama

    2014-04-01

    Full Text Available The cytosolic glutathione transferase (cytGST superfamily comprises more than 13,000 nonredundant sequences found throughout the biosphere. Their key roles in metabolism and defense against oxidative damage have led to thousands of studies over several decades. Despite this attention, little is known about the physiological reactions they catalyze and most of the substrates used to assay cytGSTs are synthetic compounds. A deeper understanding of relationships across the superfamily could provide new clues about their functions. To establish a foundation for expanded classification of cytGSTs, we generated similarity-based subgroupings for the entire superfamily. Using the resulting sequence similarity networks, we chose targets that broadly covered unknown functions and report here experimental results confirming GST-like activity for 82 of them, along with 37 new 3D structures determined for 27 targets. These new data, along with experimentally known GST reactions and structures reported in the literature, were painted onto the networks to generate a global view of their sequence-structure-function relationships. The results show how proteins of both known and unknown function relate to each other across the entire superfamily and reveal that the great majority of cytGSTs have not been experimentally characterized or annotated by canonical class. A mapping of taxonomic classes across the superfamily indicates that many taxa are represented in each subgroup and highlights challenges for classification of superfamily sequences into functionally relevant classes. Experimental determination of disulfide bond reductase activity in many diverse subgroups illustrate a theme common for many reaction types. Finally, sequence comparison between an enzyme that catalyzes a reductive dechlorination reaction relevant to bioremediation efforts with some of its closest homologs reveals differences among them likely to be associated with evolution of this

  7. Lisímetro de pesagem de grande porte.: desenvolvimento e calibração A large-scale weighting lysimeter. part I: development and calibration

    Directory of Open Access Journals (Sweden)

    Luiz F. M. de S. Campeche

    2011-05-01

    relationship between mass variation (mm and voltage (mV of the load-cell lysimeter described a linear model with minimum hysterisis. Also, it can be concluded that the methodology used for the calibration of the weighing lysimeter was appropriate, showing a coefficient of determination of 0.99 for the calibration equation. Results also indicated that the large-scale weighing lysimeter can be used with success in the determination of evapotranspiration of fruit plants.

  8. Large-Scale Total Water Storage and Water Flux Changes over the Arid and Semiarid Parts of the Middle East from GRACE and Reanalysis Products

    Science.gov (United States)

    Forootan, E.; Safari, A.; Mostafaie, A.; Schumacher, M.; Delavar, M.; Awange, J. L.

    2017-05-01

    Previous studies indicate that water storage over a large part of the Middle East has been decreased over the last decade. Variability in the total (hydrological) water flux (TWF, i.e., precipitation minus evapotranspiration minus runoff) and water storage changes of the Tigris-Euphrates river basin and Iran's six major basins (Khazar, Persian, Urmia, Markazi, Hamun, and Sarakhs) over 2003-2013 is assessed in this study. Our investigation is performed based on the TWF that are estimated as temporal derivatives of terrestrial water storage (TWS) changes from the Gravity Recovery and Climate Experiment (GRACE) products and those from the reanalysis products of ERA-Interim and MERRA-Land. An inversion approach is applied to consistently estimate the spatio-temporal changes of soil moisture and groundwater storage compartments of the seven basins during the study period from GRACE TWS, altimetry, and land surface model products. The influence of TWF trends on separated water storage compartments is then explored. Our results, estimated as basin averages, indicate negative trends in the maximums of TWF peaks that reach up to -5.2 and -2.6 (mm/month/year) over 2003-2013, respectively, for the Urmia and Tigris-Euphrates basins, which are most likely due to the reported meteorological drought. Maximum amplitudes of the soil moisture compartment exhibit negative trends of -11.1, -6.6, -6.1, -4.8, -4.7, -3.8, and -1.2 (mm/year) for Urmia, Tigris-Euphrates, Khazar, Persian, Markazi, Sarakhs, and Hamun basins, respectively. Strong groundwater storage decrease is found, respectively, within the Khazar -8.6 (mm/year) and Sarakhs -7.0 (mm/year) basins. The magnitude of water storage decline in the Urmia and Tigris-Euphrates basins is found to be bigger than the decrease in the monthly accumulated TWF indicating a contribution of human water use, as well as surface and groundwater flow to the storage decline over the study area.

  9. Prevalence and determinants of non-alcoholic fatty liver disease in lifelines: A large Dutch population cohort.

    Directory of Open Access Journals (Sweden)

    Eline H van den Berg

    Full Text Available Non-alcoholic fatty liver disease is an increasing health issue that develops rather unnoticed with obesity, type 2 diabetes mellitus and metabolic syndrome. We investigated prevalence, determinants and associated metabolic abnormalities of non-alcoholic fatty liver disease in the largest population-based cohort to date.Biochemical characteristics, type 2 diabetes mellitus and metabolic syndrome were determined in the Lifelines Cohort Study (N = 167,729, a population-based cohort in the North of the Netherlands. Non-alcoholic fatty liver disease was defined as Fatty Liver Index (FLI≥60. Exclusion criteria were age <18 years, immigrants, missing data to assess FLI and metabolic syndrome, excessive alcohol use, previous-diagnosed hepatitis or cirrhosis and non-fasting blood sampling.Out of 37,496 included participants (median age 44 years, 62.1% female, 8,259 (22.0% had a FLI≥60. Individuals with a FLI≥60 were more often male, older, obese, had higher levels of hemoglobinA1c, fasting glucose, liver enzymes, total cholesterol, low-density lipoprotein cholesterol, triglycerides, c-reactive protein and leucocytes and lower high-density lipoprotein cholesterol (all P<0.0001. Participants with a FLI≥60 showed higher prevalence of type 2 diabetes mellitus (9.3% vs. 1.4%, metabolic syndrome (54.2% vs. 6.2%, impaired renal function (20.1% vs. 8.7% and cardiovascular disease (4.6% vs. 1.6% (all P<0.0001. Multivariable logistic analysis showed that smoking, hemoglobin, leucocytes, c-reactive protein, platelets, alanine aminotransferase, alkaline phosphatase, albumin, impaired renal function (OR 1.27, 95%CI 1.15-1.41, metabolic syndrome (OR 11.89, 95%CI 11.03-12.82 and its individual components hyperglycemia (OR 2.53, 95%CI 2.34-2.72, hypertension (OR 1.89, 95%CI 1.77-2.01 and reduced high-density lipoprotein cholesterol (OR 3.44, 95%CI 3.22-3.68 were independently associated with suspected non-alcoholic fatty liver disease (all P<0.0001.Twenty

  10. Determinants of fruit and vegetable consumption among children and adolescents: a review of the literature. Part II: qualitative studies

    DEFF Research Database (Denmark)

    Krølner, Rikke; Rasmussen, Mette; Brug, Johannes

    2011-01-01

    determinants for FV intake which supplement the quantitative knowledge base: Time costs; lack of taste guarantee; satiety value; appropriate time/occasions/settings for eating FV; sensory and physical aspects; variety; visibility; methods of preparation; access to unhealthy food; the symbolic value of food...... were included if they applied qualitative methods to investigate 6-18-year-olds' perceptions of factors influencing their FV consumption. Quantitative studies, review studies, studies reported in other languages than English, and non-peer reviewed or unpublished manuscripts were excluded. The papers...

  11. Analyses of the Short Periodical Part of the Spectrum of Pole Coordinate Variations Determined by the Astrometric and Laser Technique

    Science.gov (United States)

    Kołaczek, B.; Kosek, W.; Galas, R.

    Series of BIH astrometric (BIH-ASTR) pole coordinates and of CSR LAGEOS laser ranging (CSR-LALAR) pole coordinates determined in the MERIT Campaign in the years 1972 - 1986, 1983 - 1986, respectively, have been filtered by different band pass filters consisting of the law pass Gauss filter and of the high pass Butterworth filter. Filtered residuals were analysed by the MESA-Maximum Entropy Spectra Analysis and by the Ormsby narrow band pass filters in order to find numerically modeled signals approximating these residuals in the best way.

  12. Real-time determination of the signal-to-noise ratio of partly coherent seismic time series

    DEFF Research Database (Denmark)

    Kjeldsen, Peter Møller

    1994-01-01

    it is of great practical interest to be able to monitor the S/N while the traces are recorded an approach for fast real-time determination of the S/N of seismic time series is proposed. The described method is based on an iterative procedure utilizing the trace-to-trace coherence, but unlike procedures known so...... far it uses calculated initial guesses and stop criterions. This significantly reduces the computational burden of the procedure so that real-time capabilities are obtained...

  13. Adiabatic-passage cross polarization in N-15 NMR spectroscopy of peptides weakly associated to phospholipids: Determination of large RDC

    International Nuclear Information System (INIS)

    Zandomeneghi, Giorgia; Meier, Beat H.

    2004-01-01

    Structural information can be extracted from one-bond residual dipolar couplings (RDC) measured in NMR spectra of systems in field-ordered media. RDC can be on the order of J-couplings if the anisotropy of alignment is ∼ 10 -2 , 10-fold stronger than that typically used for structural studies of water-soluble proteins. In such systems the performance of 1 H → 15 N polarization transfer methods of the INEPT type is not satisfactory. In this study we show the effectiveness of adiabatic-passage cross-polarization (APCP) in transferring the 1 H → 15 N polarization in the bicelle-associated peptide Leucine Enkephalin (Lenk). APCP is efficient both in static samples and in samples spun at the magic angle (MAS) or any other angle of the spinning axis to the magnetic field (variable-angle spinning, VAS). The anisotropic spectrum of an aligned static sample and the isotropic spectrum of the sample under MAS provide a set of possible values for the 1 H- 15 N RDC of phospholipid-associated Lenk. The unambiguous determination of the 1 H- 15 N RDC was accomplished by means of VAS experiments

  14. The determination of PCBs in Rocky Flats Type IV waste sludge by gas chromatography/electron capture detection. Part 2

    International Nuclear Information System (INIS)

    Parish, K.J.; Applegate, D.V.; Postlethwait, P.D.; Boparai, A.S.; Reedy, G.T.

    1994-12-01

    Before disposal, radioactive sludge (Type IV) from Rocky Flats Plant (RFP) must be evaluated for polychlorinated biphenyl (PCB) content. The Type IV sludge consists of organic solvents, degreasers, cutting oils, and transuranic (TRU) waste mixed with calcium silicate (MicroCel E reg-sign and Oil Dri reg-sign to form a grease or paste-like material. For laboratory testing, a nonradioactive simulated Type 17V RFP sludge was prepared at Argonne National Laboratory-East (ANL-E). This sludge has a composition similar to that expected from field samples. In an earlier effort, a simplified method was developed for extraction, cleanup of extract, and determination of PCBs in samples of simulated sludge spiked with Aroclors 1254 and 1260. The simplified method has now been used to determine the presence and quantities of other Aroclors in the simulated sludge, namely, Aroclors 10 1 6, 1221, 1232, 1242, and 1248. The accuracy and precision of the data for these Aroclors were found to be similar to the data for sludges spiked with Aroclors 1254 and 1260. Since actual sludges may vary in composition, the method was also verified by analyzing another source of Type IV simulated sludge, prepared by Argonne National Laboratory-West (ANL-W)

  15. Determining causes of genetic isolation in a large carnivore (Ursus americanus population to direct contemporary conservation measures.

    Directory of Open Access Journals (Sweden)

    Agnès Pelletier

    Full Text Available The processes leading to genetic isolation influence a population's local extinction risk, and should thus be identified before conservation actions are implemented. Natural or human-induced circumstances can result in historical or contemporary barriers to gene flow and/or demographic bottlenecks. Distinguishing between these hypotheses can be achieved by comparing genetic diversity and differentiation in isolated vs. continuous neighboring populations. In Ontario, American black bears (Ursus americanus are continuously distributed, genetically diverse, and exhibit an isolation-by-distance structuring pattern, except on the Bruce Peninsula (BP. To identify the processes that led to the genetic isolation of BP black bears, we modelled various levels of historical and contemporary migration and population size reductions using forward simulations. We compared simulation results with empirical genetic indices from Ontario black bear populations under different levels of geographic isolation, and conducted additional simulations to determine if translocations could help achieve genetic restoration. From a genetic standpoint, conservation concerns for BP black bears are warranted because our results show that: i a recent demographic bottleneck associated with recently reduced migration best explains the low genetic diversity on the BP; and ii under sustained isolation, BP black bears could lose between 70% and 80% of their rare alleles within 100 years. Although restoring migration corridors would be the most effective method to enhance long-term genetic diversity and prevent inbreeding, it is unrealistic to expect connectivity to be re-established. Current levels of genetic diversity could be maintained by successfully translocating 10 bears onto the peninsula every 5 years. Such regular translocations may be more practical than landscape restoration, because areas connecting the peninsula to nearby mainland black bear populations have been

  16. Iron Quadrangle, Brazil. Elemental concentration determined by k0-instrumental neutron activation analysis. Part 2. Kale samples

    International Nuclear Information System (INIS)

    Menezes, M.A.B.C.; Palmieri, H.E.L.; Leonel, L.V.; Nalini, H.A.Jr.; Jacimovic, R.

    2006-01-01

    The objective of this study was to evaluate the influence of mining activity on elemental concentrations in kale grown around a mining area. Two sites studied are in the Iron Quadrangle, Minas Gerais, Brazil, considered one of the richest mineral-bearing regions in the world. One site is near mineral exploration activity and the other is an ecological area. A comparator site outside the Iron Quadrangle was also analyzed. This work focused on the determination of the elemental concentrations in kale applying the k 0 -instrumental neutron activation analysis. As the Brazilian legislation specifies values for soil only, the results for kale were compared to the literature values and it was found that the vegetable does not present any health risks. (author)

  17. Genetic diversity of Taenia hydatigena in the northern part of the West Bank, Palestine as determined by mitochondrial DNA sequences.

    Science.gov (United States)

    Adwan, Kamel; Jayousi, Alaa; Abuseir, Sameh; Abbasi, Ibrahim; Adwan, Ghaleb; Jarrar, Naser

    2018-06-26

    Cysticercus tenuicollis is the metacestode of canine tapeworm Taenia hydatigena, which has been reported in domestic and wild ruminants and is causing veterinary and economic losses in the meat industry. This study was conducted to determine the sequence variation in the mitochondrial cytochrome c oxidase subunit 1 (coxl) gene in 20 isolates of T. hydatigena metacestodes (cysticercus tenuicollis) collected from northern West Bank in Palestine. Nine haplotypes were detected, with one prevailing (55%). The total haplotype diversity (0.705) and the total nucleotide diversity (0.0045) displayed low genetic diversity among our isolates. Haplotype analysis showed a star-shaped network with a centrally positioned common haplotype. The Tajima's D, and Fu and Li's statistics in cysticercus tenuicollis population of this region showed a negative value, indicating deviations from neutrality and both suggested recent population expansion for the population. The findings of this study would greatly help to implement control and preventive measures for T. hydatigena larvae infection in Palestine.

  18. Analysis of tellurium-silicon alloys. Part 1. Determination of tellurium by the reduction from perchloric acid solution

    International Nuclear Information System (INIS)

    Teperek, J.

    1977-01-01

    When 100-150 mg of tellurium is dissolved in the solution containing 20 cm 3 72 wt.% of perchloric acid, the reduction of tellurium to elementary form is possible only after adding 60-100 milimoles of HCl. The reduction is performed by adding 1 cm 3 of saturated sodium pyrosulphite solution (Na 2 S 2 O 5 ) and 10 cm 3 of 10 wt.% hydrazine hydrochloride solution (N 2 H 4 .2HCl) to 80-90 cm 3 of cold solution of Te in HClO 4 -HCl mixture. The reduction is completed after 3-5 min. of boiling. When 150-200 mg sample of Te-Si alloy is dissolved in 20 cm 3 of hot 72% per chloric acid, the separation of components is reached. Tellurium can be determinated in filtrate by proposed procedure with high accuracy and precision. (author)

  19. PARK2, a Large Common Fragile Site Gene, is Part of a Stress Response Network in Normal Cells that is Disrupted During the Development of Ovarian Cancer

    National Research Council Canada - National Science Library

    Smith, David I

    2005-01-01

    .... The central two questions that we want to address with this work are what role does the inactivation of Parkin play in the development of ovarian cancer and whether this gene functions as part...

  20. AN ATTEMPT TO DETERMINE THE RELATION BETWEEN HUCUL HORSES CONFORMATION ASSESSMENT, MOVEMENT AND COURAGE TEST RESULTS PART II. MARE FAMILIES

    Directory of Open Access Journals (Sweden)

    Jadwiga TOPCZEWSKA

    2012-01-01

    Full Text Available The objective of the research was to determine the relationship between evaluation of conformation and motion indicators and results of the Huculs’ path and also to ascertain the courage (basic and elimination of Hucul horses with their classification into mare families being taken account of. The scores of 116 horses presented for the evaluation of their exterior (championship breeding were analyzed. The assessment covered the type, body conformation, movement in walk and trot as well as overall impression and preparedness for the exhibition. Measurements of length of steps, frequency and rate of the walk and trot were performed during the tests for courage. The estimated correlation coefficients exhibited the existence of some interesting trends i.e., there was positive correlation between values for type, body conformation, movement in walk and trot and the length of steps in walk and trot in individuals representing most of mare families. The reverse was the case with horses from the Sroczka and Wyderka families. Amongst the Wrona, however, negative correlations between the grade for walk and frequency of steps in walk was observed while that of between the result of path and utility tests was positive.

  1. PARK2, a Large Common Fragile Site Gene, is Part of a Stress Response Network in Normal Cells That is Disrupted During the Development of Ovarian Cancer

    National Research Council Canada - National Science Library

    Smith, David I; Zhu, Yu

    2007-01-01

    .... The central two questions that we want to address with this work are what role does inactivation of Parkin and other large CFS genes play in the development of ovarian cancer and whether these genes...

  2. Determinantes de la elección del hospital por parte de los pacientes Factors determining patients' choice of hospital

    Directory of Open Access Journals (Sweden)

    José Joaquín Mira

    2004-06-01

    Full Text Available Objetivo: Determinar cuál es la mejor forma de informar a un paciente para que elija responsablemente el centro y el servicio sanitario, e identificar los principales factores que actuarían como motivadores de esta decisión. Sujetos y método: Se elaboró la información sobre 3 hospitales ficticios y 3 procesos patológicos (cáncer de mama, hipertrofia benigna de próstata y cataratas en 4 modalidades de presentación: 1 folleto con tablas, 1 folleto con gráficos, 3 folletos con tablas y 3 folletos con gráficos, que incluían datos acerca del personal, sobre los resultados médicos y quirúrgicos, los efectos secundarios, la satisfacción de otros pacientes y familiares, y las demandas y reclamaciones efectuadas contra el hospital. La información se suministró a una muestra de 1.259 sujetos, que cumplimentaron un cuestionario con su valoración de la información recibida. Resultados: Ante la elección de tratamiento, la mayoría de los pacientes (88% preferiría que se les informara y tomar la decisión conjuntamente con el médico. Un 64% eligió el hospital con mejores resultados clínicos. La información en un solo folleto resultó más clara mediante tablas (p Objective: To identify the best way to inform patients about centers and services so that they can make a responsible choice, and to identify which factors determine patients' decisions. Subjects and methods: Data on three illnesses (breast cancer, benign prostatic hypertrophy, and cataracts in three fictitious hospitals were shown to patients. The data were presented to 1,259 subjects through four different means: a brochure including a table, a brochure with a bar graph, three brochures with tables, and three brochures with bar graphs. Data on each of the hospitals included: professional profiles, medical and surgical outcomes, side effects, patients' and relatives' satisfaction, and hospital complaints. The subjects completed a questionnaire evaluating the information

  3. A map of the cosmic microwave background radiation from the Wilkinson Microwave Anisotropy Probe (WMAP), showing the large-scale fluctuations (the quadrupole and octopole) isolated by an analysis done partly by theorists at CERN.

    CERN Multimedia

    2004-01-01

    A recent analysis, in part by theorists working at CERN, suggests a new view of the cosmic microwave background radiation. It seems the solar system, rather than the universe, causes the radiation's large-scale fluctuations, similar to the bass in a song.

  4. Psychometric Features of the General Aptitude Test-Verbal Part (GAT-V): A Large-Scale Assessment of High School Graduates in Saudi Arabia

    Science.gov (United States)

    Dimitrov, Dimiter M.; Shamrani, Abdul Rahman

    2015-01-01

    This study examines the psychometric features of a General Aptitude Test-Verbal Part, which is used with assessments of high school graduates in Saudi Arabia. The data supported a bifactor model, with one general factor and three content domains (Analogy, Sentence Completion, and Reading Comprehension) as latent aspects of verbal aptitude.

  5. Comprehensive determination of flavouring additives and nicotine in e-cigarette refill solutions. Part II: Gas-chromatography-mass spectrometry analysis.

    Science.gov (United States)

    Aszyk, Justyna; Woźniak, Mateusz Kacper; Kubica, Paweł; Kot-Wasik, Agata; Namieśnik, Jacek; Wasik, Andrzej

    2017-09-29

    Flavouring compounds are an essential part of e-liquid products for cigarettes. In general, they are regarded as safe for ingestion, but they may have unrecognized risks when they are inhaled. In some cases, manufactures do not currently abide by the Tobacco Products Directive (2014/40/EU) and do not declare the detailed contents of e-liquids on their labels. To help evaluate the health impact of flavouring substances, there is a need for comprehensive approaches to determine their concentrations in e-liquids. For this purpose, a GC-EI-MS method was developed and validated for the simultaneous determination of 46 commonly used flavour additives in e-liquids. The proposed method performed well in terms of the key validation parameters: accuracy (84-113%), inter-/intra-day precision: 0.1-10% and 1-11%, respectively, and sensitivity (limit of detection: 3-87ng/mL). The sample preparation step was based on a simple "dilute & shoot" approach. This study is a complementary method to the LC-MS/MS procedure described in Part I. Both approaches are suitable for the comprehensive determination of 88 flavouring compounds and nicotine and can be used as tools for the rapid evaluation of the quality and safety of e-cigarette products. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. 3D printing conditions determination for feedstock used in fused filament fabrication (FFF of 17-4PH stainless steel parts

    Directory of Open Access Journals (Sweden)

    J. Gonzalez-Gutierez

    2018-01-01

    Full Text Available Fused filament fabrication combined with debinding and sintering could be an economical process for 3D printing of metal parts. In this study, compounding, filament making and FFF processing of a feedstock material containing 55 vol. % of 17-4PH stainless steel powder and a multicomponent binder system are presented. For the FFF process, processing windows of the most significant parameters, such as range of extrusion temperatures (210 to 260 °C, flow rate multipliers (150 to 200 %, and 3D printing speed multipliers (60 to 100 % were determined for a constant printing bed temperature of 60 °C.

  7. Development of local-scale high-resolution atmospheric dispersion model using large-eddy simulation. Part 3: turbulent flow and plume dispersion in building arrays

    Czech Academy of Sciences Publication Activity Database

    Nakayama, H.; Jurčáková, Klára; Nagai, H.

    2013-01-01

    Roč. 50, č. 5 (2013), s. 503-519 ISSN 0022-3131 Institutional support: RVO:61388998 Keywords : local-scale high-resolution dispersion model * nuclear emergency response system * large-eddy simulation * spatially developing turbulent boundary layer flow Subject RIV: DG - Athmosphere Sciences, Meteorology Impact factor: 1.452, year: 2013

  8. Determinants of absenteeism in public organizations: A unit-level analysis of work absence in a large Danish municipality

    DEFF Research Database (Denmark)

    Løkke Nielsen, Ann-Kristina

    2008-01-01

    This study investigates the determinants of absenteeism in a large Danish municipality. Based on a review of the literature on absence, an integrative model is developed combining the individual, the social psychological and the economic approaches. The model is tested on data from approximately 5...... frequency and the department manager's observed absence frequency, but the effect is lower and less significant. Furthermore the study shows a positive relationship between absence frequency and being a male deputy head. The contracted number of work hours also has a positive association to absence...

  9. Large deviations

    CERN Document Server

    Varadhan, S R S

    2016-01-01

    The theory of large deviations deals with rates at which probabilities of certain events decay as a natural parameter in the problem varies. This book, which is based on a graduate course on large deviations at the Courant Institute, focuses on three concrete sets of examples: (i) diffusions with small noise and the exit problem, (ii) large time behavior of Markov processes and their connection to the Feynman-Kac formula and the related large deviation behavior of the number of distinct sites visited by a random walk, and (iii) interacting particle systems, their scaling limits, and large deviations from their expected limits. For the most part the examples are worked out in detail, and in the process the subject of large deviations is developed. The book will give the reader a flavor of how large deviation theory can help in problems that are not posed directly in terms of large deviations. The reader is assumed to have some familiarity with probability, Markov processes, and interacting particle systems.

  10. The Ideal Ionic Liquid Salt Bridge for the Direct Determination of Gibbs Energies of Transfer of Single Ions, Part I: The Concept.

    Science.gov (United States)

    Radtke, Valentin; Ermantraut, Andreas; Himmel, Daniel; Koslowski, Thorsten; Leito, Ivo; Krossing, Ingo

    2018-02-23

    Described is a procedure for the thermodynamically rigorous, experimental determination of the Gibbs energy of transfer of single ions between solvents. The method is based on potential difference measurements between two electrochemical half cells with different solvents connected by an ideal ionic liquid salt bridge (ILSB). Discussed are the specific requirements for the IL with regard to the procedure, thus ensuring that the liquid junction potentials (LJP) at both ends of the ILSB are mostly canceled. The remaining parts of the LJPs can be determined by separate electromotive force measurements. No extra-thermodynamic assumptions are necessary for this procedure. The accuracy of the measurements depends, amongst others, on the ideality of the IL used, as shown in our companion paper Part II. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  11. The prediction of creep damage in type 347 weld metal. Part I: the determination of material properties from creep and tensile tests

    International Nuclear Information System (INIS)

    Spindler, M.W.

    2005-01-01

    Calculations of creep damage under conditions of strain control are often carried out using either a time fraction approach or a ductility exhaustion approach. In the case of the time fraction approach the rupture strength is used to calculate creep damage, whereas creep ductility is used in the ductility exhaustion approach. In part I of this paper the methods that are used to determine these material properties are applied to some creep and constant strain rate tests on a Type 347 weld metal. In addition, new developments to the ductility exhaustion approach are described which give improved predictions of creep damage at failure in these tests. These developments use reverse modelling to determine the most appropriate creep damage model as a function of strain rate, stress and temperature. Hence, the new approach is no longer a ductility exhaustion approach but is a true creep damage model

  12. Principal Component and Cluster Analysis for determining diversification of bottom morphology based on bathymetric profiles from Brepollen (Hornsund, Spitsbergen* The project was partly supported by The Polish Ministry of Sciences and Higher Education Grant No. N N525 350038.

    Directory of Open Access Journals (Sweden)

    Mateusz Moskalik

    2014-01-01

    Full Text Available Navigation charts of the post-glacial regions of Arctic fjords tend not to cover regions from which glaciers have retreated. Whilst research vessels can make detailed bathymetric models using multibeam echosounders, they are often too large to enter such areas. To map these regions therefore requires smaller boats carrying single beam echosounders. To obtain morphology models of equivalent quality to those generated using multibeam echosounders, new ways of processing data from single beam echosounders have to be found. The results and comprehensive analysis of such measurements conducted in Brepollen (Hornsund, Spitsbergen are presented in this article. The morphological differentiation of the seafloor was determined by calculating statistical, spectral and wavelet transformation, fractal and median filtration parameters of segments of bathymetric profiles. This set of parameters constituted the input for Principal Component Analysis and then in the form of Principal Components for the Cluster Analysis. As a result of this procedure, three morphological classes are proposed for Brepollen: (i steep slopes (southern Brepollen, (ii flat bottoms (central Brepollen and gentle slopes (the Storebreen glacier valley and the southern part of the Hornbreen glacier valley, (iii the morphologically most diverse region (the central Storebreen valley, the northern part of the Hornbreen glacier valley and the north-eastern part of central Brepollen.

  13. Determinant factors of residential consumption and perception of energy conservation: Time-series analysis by large-scale questionnaire in Suita, Japan

    International Nuclear Information System (INIS)

    Hara, Keishiro; Uwasu, Michinori; Kishita, Yusuke; Takeda, Hiroyuki

    2015-01-01

    In this study, we examined determinant factors associated with the residential consumption and perception of savings of electricity and city gas; this was based on data collected from a large-scale questionnaire sent to households in Suita, Osaka Prefecture, Japan, in two different years: 2009 and 2013. We applied an ordered logit model to determine the overall trend of the determinant factors, and then we performed a more detailed analysis in order to understand the reasons why the determinant factors changed between the two periods. Results from the ordered logit model reveal that electricity and gas consumption was primarily determined by such factors as household income, number of family members, the number of home appliances, and the perceptions of energy savings; there was not much difference between the two years, although in 2013, household income did not affect the perception of energy savings. Detailed analysis demonstrated that households with high energy consumption and those with moderate consumption are becoming polarized and that there was a growing gap between consumption behavior and the perception of conservation. The implications derived from the analyses provide an essential insight into the design of a municipal policy to induce lifestyle changes for an energy-saving society. - Highlights: • Questionnaire was conducted to households in two years for time-series analysis. • We analyzed residential energy consumption and perception of savings in households. • Determinant factors for consumption and perception of savings were identified. • Households being wasteful of energy are also found willing to cut consumption. • Policy intervention could affect consumption pattern and perception of savings.

  14. Quantitative method of viral pollution determination for large volume of water using ferric hydroxide gel impregnated on the surface of glassfibre cartridge

    Directory of Open Access Journals (Sweden)

    Akira Homma

    1974-01-01

    Full Text Available Quantitative method of viral pollution determination for large volume of water using ferric hydroxide gel impregnated on the surface of glassfibre cartridge filter. The use of ferric hydroxide gel, impregnated on the surface of glassfibre cartridge filter enable us to recover 62.5% of virus (Poliomylitis type I, Lsc strain exsogeneously added to 400 liters of tap-water. The virus concentrator system consists of four cartridge filters, in which the three first one are clarifiers, where the contaminants are removed physically, without significant virus loss at this stage. The last cartridge filter is impregnated with ferric hydroxide gel, where the virus is adsorbed. After the required volume of water has been processed, the last filter is removed from the system and the viruses are recovered from the gel, using 1 liter of glycine/NaOH buffer, at pH 11. Immediately the eluate is clarified through series of cellulose acetate membranes mounted in a 142mm Millipore filter. For the second step of virus concentration, HC1 1N is added slowly to the eluate to achieve pH 3.5-4. MgC1, is added to give a final concentration of 0.05M and the viruses are readsorbed on a 0.45 , porosity (HA cellulose acetate membrane, mounted in a 90 mm Millipore filter. The viruses are recovered using the same eluent plus 10% of fetal calf serum, to a final volume of 3 ml. In this way, it was possible to concentrate virus from 400 liters of tap-water, into 1 liter in the first stage of virus concentration and just to 3 ml of final volume in a second step. The efficiency, simplicity and low operational cost, provded by the method, make it feasible to study viral pollution of recreational and tap-water sources.Relata-se o emprego de um concentrador portátil, o qual se mostrou capaz de recuperar 62,5% dos vírus (Polio I, amostra Lsc experimentalmente dispersos em 400 litros de água, os quais foram reduzidos a 3 ml. O sistema concentrador de vírus é composto de quatro

  15. Determining the directions of increasing the innovative potential of the region by developing innovative technologies and competences when preparing and implementing large investment projects

    Directory of Open Access Journals (Sweden)

    Timur V. Kramin

    2015-12-01

    Full Text Available Objective to determine the directions of increasing the innovative potential of a region through the development of innovative technologies and competences in the process of preparation and implementation of large investment projects in the Republic of Tatarstan. Methods methodology of project management institutional approach. Results it is proved that the main largescale directions of innovative potential development in the Republic of Tatarstan as a result of preparation and implementing of Universiade 2013 in Kazan are knowledge management information technologies risk management. It is shown that in the framework of the considered innovative areas a complete system was formed of competences of employees and managers in the fields of education trade hospitality and service. Scientific novelty the key directions were defined of increasing the innovative potential of a region through the development of innovative technologies and competences in the process of preparation and implementation of large investment projects by the example of the World Summer Student Games in Kazan in 2013. Practical significance on the basis of specific examples the authors illustrate the practiceoriented mechanism of innovative potential development of a region as a result of implementation of large investment projects. nbsp

  16. SCARDEC: a new technique for the rapid determination of seismic moment magnitude, focal mechanism and source time functions for large earthquakes using body-wave deconvolution

    Science.gov (United States)

    Vallée, M.; Charléty, J.; Ferreira, A. M. G.; Delouis, B.; Vergoz, J.

    2011-01-01

    Accurate and fast magnitude determination for large, shallow earthquakes is of key importance for post-seismic response and tsumami alert purposes. When no local real-time data are available, which is today the case for most subduction earthquakes, the first information comes from teleseismic body waves. Standard body-wave methods give accurate magnitudes for earthquakes up to Mw= 7-7.5. For larger earthquakes, the analysis is more complex, because of the non-validity of the point-source approximation and of the interaction between direct and surface-reflected phases. The latter effect acts as a strong high-pass filter, which complicates the magnitude determination. We here propose an automated deconvolutive approach, which does not impose any simplifying assumptions about the rupture process, thus being well adapted to large earthquakes. We first determine the source duration based on the length of the high frequency (1-3 Hz) signal content. The deconvolution of synthetic double-couple point source signals—depending on the four earthquake parameters strike, dip, rake and depth—from the windowed real data body-wave signals (including P, PcP, PP, SH and ScS waves) gives the apparent source time function (STF). We search the optimal combination of these four parameters that respects the physical features of any STF: causality, positivity and stability of the seismic moment at all stations. Once this combination is retrieved, the integration of the STFs gives directly the moment magnitude. We apply this new approach, referred as the SCARDEC method, to most of the major subduction earthquakes in the period 1990-2010. Magnitude differences between the Global Centroid Moment Tensor (CMT) and the SCARDEC method may reach 0.2, but values are found consistent if we take into account that the Global CMT solutions for large, shallow earthquakes suffer from a known trade-off between dip and seismic moment. We show by modelling long-period surface waves of these events that

  17. Nuclear fuel technology - Tank calibration and volume determination for nuclear materials accountancy - Part 4: Accurate determination of liquid height in accountancy tanks equipped with dip tubes, slow bubbling rate

    International Nuclear Information System (INIS)

    2008-01-01

    ISO 18213 deals with the acquisition, standardization, analysis, and use of calibration to determine liquid volumes in process tanks for the accountancy of nuclear materials. This part of ISO 18213 is complementary to the other parts, ISO 18213-1 (procedural overview), ISO 18213-2 (data standardization), ISO 18213-3 (statistical methods), ISO 18213-5 (fast bubbling rate) and ISO 18213-6 (in-tank determination of liquid density). The procedure presented herein for determining liquid height from measurements of induced pressure applies specifically when a very slow bubbling rate is employed. A similar procedure that is appropriate for a fast bubbling rate is given in ISO 18213-5. Measurements of the volume and height of liquid in a process accountancy tank are often made in order to estimate or verify the tank's calibration or volume measurement equation. The calibration equation relates the response of the tank's measurement system to some independent measure of tank volume. Beginning with an empty tank, calibration data are typically acquired by introducing a series of carefully measured quantities of some calibration liquid into the tank. The quantity of liquid added, the response of the tank's measurement system, and relevant ambient conditions such as temperature are measured for each incremental addition. Several calibration runs are made to obtain data for estimating or verifying a tank's calibration or measurement equation. A procedural overview of the tank calibration and volume measurement process is given in ISO 18213-1. An algorithm for standardizing tank calibration and volume measurement data to minimize the effects of variability in ambient conditions that prevail during the measurement period is given in ISO 18213-2. The procedure presented in this part of ISO 18213 for determining the height of calibration liquid in the tank from a measurement of the pressure it induces in the tank's measurement system is a vital component of that algorithm. In some

  18. Nuclear fuel technology - Tank calibration and volume determination for nuclear materials accountancy - Part 5: Accurate determination of liquid height in accountancy tanks equipped with dip tubes, fast bubbling rate

    International Nuclear Information System (INIS)

    2008-01-01

    ISO 18213 deals with the acquisition, standardization, analysis, and use of calibration to determine liquid volumes in process tanks for the accountancy of nuclear materials. This part of ISO 18213 is complementary to the other parts, ISO 18213-1 (procedural overview), ISO 18213-2 (data standardization), ISO 18213-3 (statistical methods), ISO 18213-5 (fast bubbling rate) and ISO 18213-6 (in-tank determination of liquid density). The procedure presented herein for determining liquid height from measurements of induced pressure applies specifically when a very slow bubbling rate is employed. A similar procedure that is appropriate for a fast bubbling rate is given in ISO 18213-5. Measurements of the volume and height of liquid in a process accountancy tank are often made in order to estimate or verify the tank's calibration or volume measurement equation. The calibration equation relates the response of the tank's measurement system to some independent measure of tank volume. Beginning with an empty tank, calibration data are typically acquired by introducing a series of carefully measured quantities of some calibration liquid into the tank. The quantity of liquid added, the response of the tank's measurement system, and relevant ambient conditions such as temperature are measured for each incremental addition. Several calibration runs are made to obtain data for estimating or verifying a tank's calibration or measurement equation. A procedural overview of the tank calibration and volume measurement process is given in ISO 18213-1. An algorithm for standardizing tank calibration and volume measurement data to minimize the effects of variability in ambient conditions that prevail during the measurement period is given in ISO 18213-2. The procedure presented in this part of ISO 18213 for determining the height of calibration liquid in the tank from a measurement of the pressure it induces in the tank's measurement system is a vital component of that algorithm. In some

  19. Concentrated Solar Power as part of the European energy supply. The realization of large-scale solar power plants. Options, constraints and recommendations

    International Nuclear Information System (INIS)

    Bouwmans, I.; Carton, L.J.; Dijkema, G.P.J.; Stikkelman, R.M.; De Vries, L.J.

    2006-01-01

    Next to solar cells and solar collectors for decentralized power generation Concentrated Solar Power (CSP) technology is available and proven for large-scale application of solar energy. However, after 20 years of demonstration projects and semi-commercial installations, CSP is still not widely used. In this quick-scan an overview is given of strong and weak points of CSP, as well as its' options and constraints with regard to a sustainable energy supply, focusing on technical, economical and administrative constraints and chances in Europe and European Union member states [nl

  20. Results of PMIP2 coupled simulations of the Mid-Holocene and Last Glacial Maximum – Part 1: experiments and large-scale features

    Directory of Open Access Journals (Sweden)

    Y. Zhao

    2007-06-01

    Full Text Available A set of coupled ocean-atmosphere simulations using state of the art climate models is now available for the Last Glacial Maximum and the Mid-Holocene through the second phase of the Paleoclimate Modeling Intercomparison Project (PMIP2. This study presents the large-scale features of the simulated climates and compares the new model results to those of the atmospheric models from the first phase of the PMIP, for which sea surface temperature was prescribed or computed using simple slab ocean formulations. We consider the large-scale features of the climate change, pointing out some of the major differences between the different sets of experiments. We show in particular that systematic differences between PMIP1 and PMIP2 simulations are due to the interactive ocean, such as the amplification of the African monsoon at the Mid-Holocene or the change in precipitation in mid-latitudes at the LGM. Also the PMIP2 simulations are in general in better agreement with data than PMIP1 simulations.

  1. The impact of study design and diagnostic approach in a large multi-centre ADHD study: Part 2: Dimensional measures of psychopathology and intelligence

    Directory of Open Access Journals (Sweden)

    Roeyers Herbert

    2011-04-01

    Full Text Available Abstract Background The International Multi-centre ADHD Genetics (IMAGE project with 11 participating centres from 7 European countries and Israel has collected a large behavioural and genetic database for present and future research. Behavioural data were collected from 1068 probands with ADHD and 1446 unselected siblings. The aim was to describe and analyse questionnaire data and IQ measures from all probands and siblings. In particular, to investigate the influence of age, gender, family status (proband vs. sibling, informant, and centres on sample homogeneity in psychopathological measures. Methods Conners' Questionnaires, Strengths and Difficulties Questionnaires, and Wechsler Intelligence Scores were used to describe the phenotype of the sample. Data were analysed by use of robust statistical multi-way procedures. Results Besides main effects of age, gender, informant, and centre, there were considerable interaction effects on questionnaire data. The larger differences between probands and siblings at home than at school may reflect contrast effects in the parents. Furthermore, there were marked gender by status effects on the ADHD symptom ratings with girls scoring one standard deviation higher than boys in the proband sample but lower than boys in the siblings sample. The multi-centre design is another important source of heterogeneity, particularly in the interaction with the family status. To a large extent the centres differed from each other with regard to differences between proband and sibling scores. Conclusions When ADHD probands are diagnosed by use of fixed symptom counts, the severity of the disorder in the proband sample may markedly differ between boys and girls and across age, particularly in samples with a large age range. A multi-centre design carries the risk of considerable phenotypic differences between centres and, consequently, of additional heterogeneity of the sample even if standardized diagnostic procedures are

  2. The impact of study design and diagnostic approach in a large multi-centre ADHD study: Part 2: Dimensional measures of psychopathology and intelligence.

    LENUS (Irish Health Repository)

    Muller, Ueli C

    2011-04-07

    Abstract Background The International Multi-centre ADHD Genetics (IMAGE) project with 11 participating centres from 7 European countries and Israel has collected a large behavioural and genetic database for present and future research. Behavioural data were collected from 1068 probands with ADHD and 1446 unselected siblings. The aim was to describe and analyse questionnaire data and IQ measures from all probands and siblings. In particular, to investigate the influence of age, gender, family status (proband vs. sibling), informant, and centres on sample homogeneity in psychopathological measures. Methods Conners\\' Questionnaires, Strengths and Difficulties Questionnaires, and Wechsler Intelligence Scores were used to describe the phenotype of the sample. Data were analysed by use of robust statistical multi-way procedures. Results Besides main effects of age, gender, informant, and centre, there were considerable interaction effects on questionnaire data. The larger differences between probands and siblings at home than at school may reflect contrast effects in the parents. Furthermore, there were marked gender by status effects on the ADHD symptom ratings with girls scoring one standard deviation higher than boys in the proband sample but lower than boys in the siblings sample. The multi-centre design is another important source of heterogeneity, particularly in the interaction with the family status. To a large extent the centres differed from each other with regard to differences between proband and sibling scores. Conclusions When ADHD probands are diagnosed by use of fixed symptom counts, the severity of the disorder in the proband sample may markedly differ between boys and girls and across age, particularly in samples with a large age range. A multi-centre design carries the risk of considerable phenotypic differences between centres and, consequently, of additional heterogeneity of the sample even if standardized diagnostic procedures are used. These

  3. Development of tsunami fragility evaluation methods by large scale experiments. Part 2. Validation of the applicability of evaluation methods of impact force due to tsunami floating debris

    International Nuclear Information System (INIS)

    Takabatake, Daisuke; Kihara, Naoto; Kaida, Hideki; Miyagawa, Yoshinori; Ikeno, Masaaki; Shibayama, Atsushi

    2015-01-01

    In order to examine the applicability of the existing estimation equations of the impact force due to tsunami floating debris, the collision tests are carried out. In the experiments, logs and full-scale light car are used. In this report, two types of existing equations, one is based on the Young's module of the debris (Eq.A) and the other one is based on the stiffness of the debris (Eq.B), are focused on. The estimated impact forces using Eq.A with log's Young module obtained by the material test agree with measured forces obtained by the collision test. But Eq.A does not applicate to a car because it is not easy to determine the Young's module of a car. On the other hand, the estimated impact forces using Eq.B with car's stiffness obtained by the static loading test agree with measured forces obtained by the collision test. This indicates that Eq.B unable us to estimate impact force of the floating debris such as car if the stiffness of the debris is determined. (author)

  4. Performance and Feasibility Analysis of a Grid Interactive Large Scale Wind/PV Hybrid System based on Smart Grid Methodology Case Study South Part – Jordan

    Directory of Open Access Journals (Sweden)

    Qais H. Alsafasfeh

    2015-02-01

    Full Text Available Most recent research on renewable energy resources main one goal to make Jordan less dependent on imported energy with locally developed and produced solar power, this paper discussed the efficient system of Wind/ PV Hybrid System to be than main power sources for south part of Jordan, the proposed hybrid system design based on Smart Grid Methodology,  the solar energy will be installed on top roof of  electricity subscribers across the Governorate of Maan, Tafila, Karak and Aqaba and the wind energy will set in one site by this way the capital cost for project will be reduced also the  simulation result show   the feasibility  is a very competitive and feasible cost . Economics analysis of a proposed renewable energy system was made using HOMER simulation and evaluation was completed with the cost per kilowatt of EDCO company, the net present cost is $2,551,676,416, the cost of energy is 0.07kWhr with a renewable fraction of 86.6 %.

  5. Deeply Bound 1s and 2p Pionic States in 205Pb and Determination of the s-Wave Part of the Pion-Nucleus Interaction

    Science.gov (United States)

    Geissel, H.; Gilg, H.; Gillitzer, A.; Hayano, R. S.; Hirenzaki, S.; Itahashi, K.; Iwasaki, M.; Kienle, P.; Münch, M.; Münzenberg, G.; Schott, W.; Suzuki, K.; Tomono, D.; Weick, H.; Yamazaki, T.; Yoneyama, T.

    2002-03-01

    We observed well-separated 1s and 2p π- states in 205Pb in the 206Pb(d,3He) reaction at Td = 604.3 MeV. The binding energies and the widths determined are B1s = 6.762+/-0.061 MeV, Γ1s = 0.764+0.171-0.154 MeV, B2p = 5.110+/-0.045 MeV, and Γ2p = 0.321+0.060-0.062 MeV. They are used to deduce the real and imaginary strengths of the s-wave part of the pion-nucleus interaction, which translates into a positive mass shift of π- in 205Pb.

  6. Determination of electron temperature and density at plasma edge in the Large Helical Device with opacity-incorporated helium collisional-radiative model

    International Nuclear Information System (INIS)

    Goto, M.; Sawada, K.

    2014-01-01

    Spectra of neutral helium in the visible wavelength range are measured for a discharge in the Large Helical Device (LHD). The electron temperature (T e ) and density (n e ) are derived from the intensity distribution of helium emission lines. For that purpose, a collisional-radiative model developed by Sawada et al. [Plasma and Fusion Res. 2010;5:001] which takes the reabsorption effect into account is used. It is found that incorporation of the reabsorption effect is necessary to obtain a set of T e and n e giving consistent line intensity distribution with the measurement, and that those parameters obtained vary as the line-averaged n e changes in the course of time. The position where the helium line emission dominantly takes place is located with the help of T e and n e profiles measured by the Thomson scattering system. The result indicates that the emission position is almost fixed at the place where the connection length of the magnetic field lines to the divertor plate leaps beyond 10 m. Because intense neutral atom line emission suggests the vigorous ionization of neutral atoms, the helium line emission location determined here can be regarded as the effective boundary of the plasma. - Highlights: • The reabsorption effect is included in the helium collisional-radiative model. • Electron temperature and density are derived for the Large Helical Device (LHD). • Line emission location is found to be little changed during the discharge. • This measurement method can be used to determine the position of effective plasma boundary

  7. A Fragment-Based Ligand Screen Against Part of a Large Protein Machine: The ND1 Domains of the AAA+ ATPase p97/VCP.

    Science.gov (United States)

    Chimenti, Michael S; Bulfer, Stacie L; Neitz, R Jeffrey; Renslo, Adam R; Jacobson, Matthew P; James, Thomas L; Arkin, Michelle R; Kelly, Mark J S

    2015-07-01

    The ubiquitous AAA+ ATPase p97 functions as a dynamic molecular machine driving several cellular processes. It is essential in regulating protein homeostasis, and it represents a potential drug target for cancer, particularly when there is a greater reliance on the endoplasmic reticulum-associated protein degradation pathway and ubiquitin-proteasome pathway to degrade an overabundance of secreted proteins. Here, we report a case study for using fragment-based ligand design approaches against this large and dynamic hexamer, which has multiple potential binding sites for small molecules. A screen of a fragment library was conducted by surface plasmon resonance (SPR) and followed up by nuclear magnetic resonance (NMR), two complementary biophysical techniques. Virtual screening was also carried out to examine possible binding sites for the experimental hits and evaluate the potential utility of fragment docking for this target. Out of this effort, 13 fragments were discovered that showed reversible binding with affinities between 140 µM and 1 mM, binding stoichiometries of 1:1 or 2:1, and good ligand efficiencies. Structural data for fragment-protein interactions were obtained with residue-specific [U-(2)H] (13)CH3-methyl-labeling NMR strategies, and these data were compared to poses from docking. The combination of virtual screening, SPR, and NMR enabled us to find and validate a number of interesting fragment hits and allowed us to gain an understanding of the structural nature of fragment binding. © 2015 Society for Laboratory Automation and Screening.

  8. Interzonal air and moisture transport through large horizontal openings in a full-scale two-story test-hut: Part 2 - CFD study

    Energy Technology Data Exchange (ETDEWEB)

    Vera, S. [Department of Building, Civil and Environmental Engineering, Concordia University, 1455 de Maisonneuve Blvd. West, Montreal, Quebec (Canada); Department of Construction Engineering and Management, Pontificia Universidad Catolica de Chile, Av. Vicuna Mackenna 4860, San Agustin building, 3rd floor, Campus San Joaquin, Macul, Santiago 6904411 (Chile); Fazio, P.; Rao, J. [Department of Building, Civil and Environmental Engineering, Concordia University, 1455 de Maisonneuve Blvd. West, Montreal, Quebec (Canada)

    2010-03-15

    The aim of this paper is to study the air and moisture transport through a large horizontal opening in a full-scale two-story test-hut with mixed ventilation by means of computational fluid dynamics (CFD) simulations. CFD allows extending the experimental study presented in the companion paper and overcoming some limitations of experimental data. More than 80 cases were simulated for conditions similar to those tested experimentally and for additional ventilation rates and temperature difference between the two rooms. CFD simulations were performed in Airpak and the indoor zero-equation turbulence model was used. The CFD model was extensively validated with the distributions of air speed, temperature and humidity ratio measured across the two rooms, as well as with the measured interzonal mass airflows through the horizontal opening. CFD simulation results show that temperature difference between the two rooms and ventilation rate strongly influence the interzonal mass airflows through the opening when the upper room is colder than the lower room, while warm convective air currents from the baseboard heater and from the moisture source placed in the lower room cause upward mass airflows when the upper room is warmer than the lower room. Finally, empirical relationships between the upward mass airflow and the temperature difference between the two rooms are developed. (author)

  9. Fire simulation in large compartments with a fire model 'CFAST'. Part 1. Survey of applicability for analyzing air-temperature profile in compartments

    International Nuclear Information System (INIS)

    Hattori, Yasuo; Suto, Hitoshi; Shirai, Koji; Eguchi, Yuzuru; Sano, Tadashi

    2012-01-01

    The basic performance of numerical analysis of air-temperature profiles in large-scale compartments by using a zone model, CFAST (Consolidated model of Fire growth And Smoke Transport), which has been widely applied for fire protection design of buildings is examined. Special attentions are paid to the dependence of the setting boundary conditions and the choosing model parameters. The simulations carried out under the denkyoken-test conditions, in which the air-temperature profiles in compartments and the heat-release rate of a fire have been precisely measured, indicate that the CFAST has a capability to appropriately represent the time-histories of air-temperature in the high air-temperature layer generated in the vicinity of ceiling of the compartment which includes the source of a fire, by applying the proper boundary conditions, i.e., time-histories of air-temperature in the upper (high temperature) layer given by the CFAST agree well with those of observations. The sensitivity analysis in the simulations also reveals that the appropriately setting of the boundary-conditions, especially for the heat-release ratio from a fire and the heat-transfer rate from walls of compartments to ambient air is vital. Contrary to this, the impacts of choosing numerical parameters on the air-temperature analysis are quite small. (author)

  10. Automated transport and sorting system in a large reference laboratory: part 1. Evaluation of needs and alternatives and development of a plan.

    Science.gov (United States)

    Hawker, Charles D; Garr, Susan B; Hamilton, Leslie T; Penrose, John R; Ashwood, Edward R; Weiss, Ronald L

    2002-10-01

    Our laboratory, a large, commercial, esoteric reference laboratory, sought some form of total laboratory automation to keep pace with rapid growth of specimen volumes as well as to meet competitive demands for cost reduction and improved turnaround time. We conducted a systematic evaluation of our needs, which led to the development of a plan to implement an automated transport and sorting system. We systematically analyzed and studied our specimen containers, test submission requirements and temperatures, and the workflow and movement of people, specimens, and information throughout the laboratory. We performed an intricate timing study that identified bottlenecks in our manual handling processes. We also evaluated various automation options. The automation alternative viewed to best meet our needs was a transport and sorting system from MDS AutoLab. Our comprehensive plan also included a new standardized transport tube; a centralized automated core laboratory for higher volume tests; a new "automation-friendly" software system for order entry, tracking, and process control; a complete reengineering of our order-entry, handling, and tracking processes; and remodeling of our laboratory facility and specimen processing area. The scope of this project and its potential impact on overall laboratory operations and performance justified the extensive time we invested (nearly 4 years) in a systematic approach to the evaluation, design, and planning of this project.

  11. Rapidly progressive renal disease as part of Wolfram syndrome in a large inbred Turkish family due to a novel WFS1 mutation (p.Leu511Pro).

    Science.gov (United States)

    Yuca, Sevil Ari; Rendtorff, Nanna Dahl; Boulahbel, Houda; Lodahl, Marianne; Tranebjærg, Lisbeth; Cesur, Yasar; Dogan, Murat; Yilmaz, Cahide; Akgun, Cihangir; Acikgoz, Mehmet

    2012-01-01

    Wolfram syndrome, also named "DIDMOAD" (diabetes insipidus, diabetes mellitus, optic atrophy, and deafness), is an inherited association of juvenile-onset diabetes mellitus and optic atrophy as key diagnostic criteria. Renal tract abnormalities and neurodegenerative disorder may occur in the third and fourth decade. The wolframin gene, WFS1, associated with this syndrome, is located on chromosome 4p16.1. Many mutations have been described since the identification of WFS1 as the cause of Wolfram syndrome. We identified a new homozygous WFS1 mutation (c.1532T>C; p.Leu511Pro) causing Wolfram syndrome in a large inbred Turkish family. The patients showed early onset of IDDM, diabetes insipidus, optic atrophy, sensorineural hearing impairment and very rapid progression to renal failure before age 12 in three females. Ectopic expression of the wolframin mutant in HEK cells results in greatly reduced levels of protein expression compared to wild-type wolframin, strongly supporting that this mutation is disease-causing. The mutation showed perfect segregation with disease in the family, characterized by early and severe clinical manifestations. Copyright © 2011 Elsevier Masson SAS. All rights reserved.

  12. Enantioselective column coupled electrophoresis employing large bore capillaries hyphenated with tandem mass spectrometry for ultra-trace determination of chiral compounds in complex real samples.

    Science.gov (United States)

    Piešťanský, Juraj; Maráková, Katarína; Kovaľ, Marián; Havránek, Emil; Mikuš, Peter

    2015-12-01

    A new multidimensional analytical approach for the ultra-trace determination of target chiral compounds in unpretreated complex real samples was developed in this work. The proposed analytical system provided high orthogonality due to on-line combination of three different methods (separation mechanisms), i.e. (1) isotachophoresis (ITP), (2) chiral capillary zone electrophoresis (chiral CZE), and (3) triple quadrupole mass spectrometry (QqQ MS). The ITP step, performed in a large bore capillary (800 μm), was utilized for the effective sample pretreatment (preconcentration and matrix clean-up) in a large injection volume (1-10 μL) enabling to obtain as low as ca. 80 pg/mL limits of detection for the target enantiomers in urine matrices. In the chiral CZE step, the different chiral selectors (neutral, ionizable, and permanently charged cyclodextrins) and buffer systems were tested in terms of enantioselectivity and influence on the MS detection response. The performance parameters of the optimized ITP - chiral CZE-QqQ MS method were evaluated according to the FDA guidance for bioanalytical method validation. Successful validation and application (enantioselective monitoring of renally eliminated pheniramine and its metabolite in human urine) highlighted great potential of this chiral approach in advanced enantioselective biomedical applications. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. DURATION OF GRANITOID MAGMATISM IN PERIPHERAL PARTS OF LARGE IGNEOUS PROVINCES (BASED ON 40AR/39AR ISOTOPIC STUDIES OF ALTAI PERMIAN-TRIASSIC GRANITOIDS

    Directory of Open Access Journals (Sweden)

    O. A. Gavryushkina

    2017-01-01

    Full Text Available In large igneous provinces (LIP of fold areas, granitoid rocks are dominant, while mantle-derivated rocks play a subordinate role in rock formation. If magma emissions are impulsive, it may take 25–30 million years for a LIP to form and take shape. In this paper, we present the results of 40Ar/39Ar isotopic studies of Permian-Triassic grani­toids in the Altai region, Russia, and clarify the evolution of this region located at the periphery of the Siberian LIP. These granitoids are very diverse and differ not only in their rock set, but also in the composition features. In the study region, the granodiorite-granite and granite-leucogranite association with the characteristics of I- and S-types as well rare metal ore-bearing leucogranites are observed along with gabbro- and syenite-granite series, including mafic and intermediate rocks with the A2-type geochemical features. The 40Ar/39Ar data obtained in our study suggest that most of the studied granitoids intruded within a short period of time, 254–247 Ma. This timeline is closely related to the formation of granitoids in theKuznetsk basin and dolerite dikes in the Terekta complex (251–248 and 255±5 Ma, respectively, as well as intrusions of lamproite and lamprophyre dikes of the Chuya complex (245–242 and 237–235 Ma. Thus, we conclude that the Altai Permian-Triassic granitoids are varied mainly due to the evolution of mafic magmatism.

  14. Climatology of summer midtropospheric perturbations in the US northern plains. Part II: large-scale effects of the Rocky Mountains on genesis

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Shih-Yu. [Iowa State University, Department of Geological and Atmospheric Sciences, Ames, IA (United States); Utah State University, Utah Climate Center, Logan, UT (United States); Chen, Tsing-Chang [Iowa State University, Department of Geological and Atmospheric Sciences, Ames, IA (United States); Takle, Eugene S. [Iowa State University, Department of Geological and Atmospheric Sciences, Ames, IA (United States); Iowa State University, Department of Agronomy, Ames, IA (United States)

    2011-04-15

    Propagating convective storms across the US northern plains are often coupled with preexisting midtropospheric perturbations (MPs) initiated over the Rocky Mountains. A companion study (Part I) notes that such MPs occur most commonly at 12 UTC (early morning) and 00 UTC (late afternoon). Using a regional reanalysis and a general circulation model (GCM), this study investigates how such a bimodal distribution of the MP frequency is formed. The results point to two possible mechanisms working together while each has a different timing in terms of maximum effect. The diurnal evolutions between the midtropospheric flows over the Rockies and over the Great Plains are nearly out-of-phase due to inertial oscillation. During the nighttime, the westerly flows at 700-500 mb over the Rockies intensify while flows at the same level over the Great Plains turn easterly. These two flows converge over the eastern Rockies and induce cyclonic vorticity through vortex stretching. After sunrise, the convergence dissipates and the cyclonic vorticity is redistributed by horizontal vorticity advection, moving it downstream. This process creates a climatological zonally propagating vorticity signal which, in turn, facilitates the early-morning MP genesis at 12 UTC. The analysis also reveals marked dynamic instability conducive to subsynoptic-scale disturbances in the midtroposphere over the Rockies. Strong meridional temperature gradients appear over the north-facing slopes of the Rockies due to terrain heating to the south and the presence of cooler air to the north. This feature, along with persistent vertical shear, creates a Charney-Stern type of instability (i.e. sign changes of the meridional potential vorticity gradient). Meanwhile, the development of terrain boundary layer reduces the Rossby deformation radius which, subsequently, enhances the likelihood for baroclinic short waves. Such effects are most pronounced in the late afternoon and therefore are supportive to the MP

  15. DETERMINATION OF THE POINT-SPREAD FUNCTION FOR THE FERMI LARGE AREA TELESCOPE FROM ON-ORBIT DATA AND LIMITS ON PAIR HALOS OF ACTIVE GALACTIC NUCLEI

    Energy Technology Data Exchange (ETDEWEB)

    Ackermann, M. [Deutsches Elektronen Synchrotron DESY, D-15738 Zeuthen (Germany); Ajello, M.; Allafort, A.; Bechtol, K.; Bloom, E. D.; Borgland, A. W.; Bottacini, E.; Buehler, R. [W. W. Hansen Experimental Physics Laboratory, Kavli Institute for Particle Astrophysics and Cosmology, Department of Physics and SLAC National Accelerator Laboratory, Stanford University, Stanford, CA 94305 (United States); Asano, K. [Interactive Research Center of Science, Tokyo Institute of Technology, Meguro City, Tokyo 152-8551 (Japan); Atwood, W. B. [Santa Cruz Institute for Particle Physics, Department of Physics and Department of Astronomy and Astrophysics, University of California at Santa Cruz, Santa Cruz, CA 95064 (United States); Baldini, L.; Bellazzini, R.; Bregeon, J. [Istituto Nazionale di Fisica Nucleare, Sezione di Pisa, I-56127 Pisa (Italy); Ballet, J. [Laboratoire AIM, CEA-IRFU/CNRS/Universite Paris Diderot, Service d' Astrophysique, CEA Saclay, F-91191 Gif sur Yvette (France); Barbiellini, G. [Istituto Nazionale di Fisica Nucleare, Sezione di Trieste, I-34127 Trieste (Italy); Bastieri, D. [Istituto Nazionale di Fisica Nucleare, Sezione di Padova, I-35131 Padova (Italy); Bonamente, E. [Istituto Nazionale di Fisica Nucleare, Sezione di Perugia, I-06123 Perugia (Italy); Brandt, T. J. [CNRS, IRAP, F-31028 Toulouse cedex 4 (France); Brigida, M. [Dipartimento di Fisica ' M. Merlin' dell' Universita e del Politecnico di Bari, I-70126 Bari (Italy); Bruel, P., E-mail: mdwood@slac.stanford.edu, E-mail: mar0@uw.edu [Laboratoire Leprince-Ringuet, Ecole polytechnique, CNRS/IN2P3, F-91128 Palaiseau (France); and others

    2013-03-01

    The Large Area Telescope (LAT) on the Fermi Gamma-ray Space Telescope is a pair-conversion telescope designed to detect photons with energies from Almost-Equal-To 20 MeV to >300 GeV. The pre-launch response functions of the LAT were determined through extensive Monte Carlo simulations and beam tests. The point-spread function (PSF) characterizing the angular distribution of reconstructed photons as a function of energy and geometry in the detector is determined here from two years of on-orbit data by examining the distributions of {gamma} rays from pulsars and active galactic nuclei (AGNs). Above 3 GeV, the PSF is found to be broader than the pre-launch PSF. We checked for dependence of the PSF on the class of {gamma}-ray source and observation epoch and found none. We also investigated several possible spatial models for pair-halo emission around BL Lac AGNs. We found no evidence for a component with spatial extension larger than the PSF and set upper limits on the amplitude of halo emission in stacked images of low- and high-redshift BL Lac AGNs and the TeV blazars 1ES0229+200 and 1ES0347-121.

  16. Determination of sub-parts per billion levels of copper in complex matrices by adsorptive string voltammetry on a mercury electrode

    International Nuclear Information System (INIS)

    Shahbaazi, H.R.; Shahbaazi, H.R.; Safavi, A.; Maleki, N.

    2008-01-01

    The voltammetric characteristics of Cu(II)-SSA complex at the mercury electrode were investigated. An analytical method that based on the adsorptive accumulation of Cu(II)-SSA complex followed by the reduction of the complexed copper was developed for the copper determination in complex matrices in presence of the large amount of foreign ions. Adsorptive voltammetry determination showed that the Cu(II)-SSA complex behaves irreversibly exchanging two electrons on the hanging mercury drop electrode (HMDE). Factor affecting on the complextion, accumulation and stripping steps were studied and a procedure was developed. The instrumental parameters in the measurement step were also tested. The optimum conditions of pH, SSA concentration, accumulation potential and accumulation time were studied. Under optimal conditions (pH=12.9 glycin Buffer, 7 x 10 - '3 M SSA and accumulation potential -100 mV vs. Ag/ AgCl), a linear calibration graph in the range 1.25 μg L -1 to 42.5 μg L'- 1 and a detection limit of 0.8 μ L -1 were obtained. The average relative standard deviation (RSD) for seven determinations was calculated as 7 %, 5.5 % and 3 % for the concentrations between 3, 15 and 23 μg L'- 1 . The effect of foreign ions and surfactants on the peak height of Cu(II)-SSA complex was evaluated. The method was applied for the determination of the copper in different real samples such as crude oil, crude oil tank button sludge, waste water and tap water samples. The accuracy of the results was checked by ICP. (author)

  17. Parameterization of sheared entrainment in a well-developed CBL. Part I: Evaluation of the scheme through large-eddy simulations

    Science.gov (United States)

    Liu, Peng; Sun, Jianning; Shen, Lidu

    2016-10-01

    The entrainment flux ratio A e and the inversion layer (IL) thickness are two key parameters in a mixed layer model. A e is defined as the ratio of the entrainment heat flux at the mixed layer top to the surface heat flux. The IL is the layer between the mixed layer and the free atmosphere. In this study, a parameterization of A e is derived from the TKE budget in the firstorder model for a well-developed CBL under the condition of linearly sheared geostrophic velocity with a zero value at the surface. It is also appropriate for a CBL under the condition of geostrophic velocity remaining constant with height. LESs are conducted under the above two conditions to determine the coefficients in the parameterization scheme. Results suggest that about 43% of the shear-produced TKE in the IL is available for entrainment, while the shear-produced TKE in the mixed layer and surface layer have little effect on entrainment. Based on this scheme, a new scale of convective turbulence velocity is proposed and applied to parameterize the IL thickness. The LES outputs for the CBLs under the condition of linearly sheared geostrophic velocity with a non-zero surface value are used to verify the performance of the parameterization scheme. It is found that the parameterized A e and IL thickness agree well with the LES outputs.

  18. The determination of radioactive contamination level in Korean food. Part of a coordinated programme on environmental monitoring for radiological protection in Asia and the Far East

    International Nuclear Information System (INIS)

    Kang, Y.H.

    1979-03-01

    This study was performed from July, 1974 till May, 1978 to observe the Sr-90 concentration in Korean foodstuffs which were grown in Central district, Honam district, Youngnam district, and several islands (I.) districts; Ulnung I., Hucksan I. and Jeju I. The contamination levels in rice, barley, cultivated vegetables, and wild edible vegetables in Korea were studied. The results obtained were as follows; in the radiochemical determination of Sr-90 in rice and barley samples in 1977, it were estimated 14.7+-7.3 - 58.1+-20.9 pCi/gm-Ca, and 15.7+-3.5 - 90.9+-41.8 pCi/gm-Ca, respectively. The average values of the rice sample and the barley sample showed 34.2+-18.8 pCi/gm-Ca, and 52.5+-30.8 pCi/gm-Ca. In the radiochemical determination of Sr-90 in the cultivated vegetable samples and the wild edible vegetable samples, it were resulted that the cultivated vegetable samples showed 130.9+-2.1 pCi/gm-Ca and the wild edible vegetable sample showed 221.6+-2.2 pCi/gm-Ca. The contamination level by the part of plant were as followed; 153.4+-2.0 pCi/gm-Ca in leaf, 310.2+-3.3 pCi/gm-Ca in root and 131.4+-3.8 pCi/gm-Ca in fruit. (author)

  19. The impact of study design and diagnostic approach in a large multi-centre ADHD study. Part 1: ADHD symptom patterns

    Directory of Open Access Journals (Sweden)

    Roeyers Herbert

    2011-04-01

    Full Text Available Abstract Background The International Multi-centre ADHD Genetics (IMAGE project with 11 participating centres from 7 European countries and Israel has collected a large behavioural and genetic database for present and future research. Behavioural data were collected from 1068 probands with the combined type of attention deficit/hyperactivity disorder (ADHD-CT and 1446 'unselected' siblings. The aim was to analyse the IMAGE sample with respect to demographic features (gender, age, family status, and recruiting centres and psychopathological characteristics (diagnostic subtype, symptom frequencies, age at symptom detection, and comorbidities. A particular focus was on the effects of the study design and the diagnostic procedure on the homogeneity of the sample in terms of symptom-based behavioural data, and potential consequences for further analyses based on these data. Methods Diagnosis was based on the Parental Account of Childhood Symptoms (PACS interview and the DSM-IV items of the Conners' teacher questionnaire. Demographics of the full sample and the homogeneity of a subsample (all probands were analysed by using robust statistical procedures which were adjusted for unequal sample sizes and skewed distributions. These procedures included multi-way analyses based on trimmed means and winsorised variances as well as bootstrapping. Results Age and proband/sibling ratios differed between participating centres. There was no significant difference in the distribution of gender between centres. There was a significant interaction between age and centre for number of inattentive, but not number of hyperactive symptoms. Higher ADHD symptom frequencies were reported by parents than teachers. The diagnostic symptoms differed from each other in their frequencies. The face-to-face interview was more sensitive than the questionnaire. The differentiation between ADHD-CT probands and unaffected siblings was mainly due to differences in hyperactive

  20. The impact of study design and diagnostic approach in a large multi-centre ADHD study. Part 1: ADHD symptom patterns.

    LENUS (Irish Health Repository)

    Muller, Ueli C

    2011-04-07

    Abstract Background The International Multi-centre ADHD Genetics (IMAGE) project with 11 participating centres from 7 European countries and Israel has collected a large behavioural and genetic database for present and future research. Behavioural data were collected from 1068 probands with the combined type of attention deficit\\/hyperactivity disorder (ADHD-CT) and 1446 \\'unselected\\' siblings. The aim was to analyse the IMAGE sample with respect to demographic features (gender, age, family status, and recruiting centres) and psychopathological characteristics (diagnostic subtype, symptom frequencies, age at symptom detection, and comorbidities). A particular focus was on the effects of the study design and the diagnostic procedure on the homogeneity of the sample in terms of symptom-based behavioural data, and potential consequences for further analyses based on these data. Methods Diagnosis was based on the Parental Account of Childhood Symptoms (PACS) interview and the DSM-IV items of the Conners\\' teacher questionnaire. Demographics of the full sample and the homogeneity of a subsample (all probands) were analysed by using robust statistical procedures which were adjusted for unequal sample sizes and skewed distributions. These procedures included multi-way analyses based on trimmed means and winsorised variances as well as bootstrapping. Results Age and proband\\/sibling ratios differed between participating centres. There was no significant difference in the distribution of gender between centres. There was a significant interaction between age and centre for number of inattentive, but not number of hyperactive symptoms. Higher ADHD symptom frequencies were reported by parents than teachers. The diagnostic symptoms differed from each other in their frequencies. The face-to-face interview was more sensitive than the questionnaire. The differentiation between ADHD-CT probands and unaffected siblings was mainly due to differences in hyperactive

  1. Instantons and Large N

    Science.gov (United States)

    Mariño, Marcos

    2015-09-01

    Preface; Part I. Instantons: 1. Instantons in quantum mechanics; 2. Unstable vacua in quantum field theory; 3. Large order behavior and Borel summability; 4. Non-perturbative aspects of Yang-Mills theories; 5. Instantons and fermions; Part II. Large N: 6. Sigma models at large N; 7. The 1=N expansion in QCD; 8. Matrix models and matrix quantum mechanics at large N; 9. Large N QCD in two dimensions; 10. Instantons at large N; Appendix A. Harmonic analysis on S3; Appendix B. Heat kernel and zeta functions; Appendix C. Effective action for large N sigma models; References; Author index; Subject index.

  2. An anatomical study of wormian bones from the eastern part of India: is genetic influence a primary determinant of their morphogenesis?

    Science.gov (United States)

    Ghosh, Sanjib Kumar; Biswas, Sudipa; Sharma, Suranjali; Chakraborty, Soumya

    2017-06-01

    Over the years a number of investigators have analysed the morphology of wormian bones in different population groups across the world. There have been significant variations between findings reported in these studies, and this has prompted researchers to focus on the influence of genetic factors on the morphology of these bones. In the light of the above observation, we considered it justified to conduct anatomical studies on wormian bones in different population groups; hence, we undertook the present study to look into the morphological details of these bones among a population in the eastern part of India. We observed a total of 120 adult dry human skulls of unknown age and sex, and noted the anatomical details of wormian bones when present. It was observed that wormian bones were present in 45 % of skulls, and that 30 % of skulls had more than one wormian bone. We also found that 2.5 % of the skulls had ten or more wormian bones, which is considered as pathognomonic. Maximum incidence (53.33 %) was observed at the lambdoid suture and minimum incidence at the bregma and metopic suture (0.61 % in each case). We noted a high incidence (21.21 %) of Inca bone/lambdoid ossicle, and bilaterally symmetrical wormian bones were present in 12.5 % study skulls. There were statistically significant (P variations between the findings of the present study and values reported in previous studies conducted in other regions of India and different parts of the world. Our observations favour the view that genetic influence primarily determines the morphology of wormian bones.

  3. Determination of the Clean Air Delivery Rate (CADR of Photocatalytic Oxidation (PCO Purifiers for Indoor Air Pollutants Using a Closed-Loop Reactor. Part II: Experimental Results

    Directory of Open Access Journals (Sweden)

    Valérie Héquet

    2017-03-01

    Full Text Available The performances of a laboratory PhotoCatalytic Oxidation (PCO device were determined using a recirculation closed-loop pilot reactor. The closed-loop system was modeled by associating equations related to two ideal reactors: a perfectly mixed reservoir with a volume of VR = 0.42 m3 and a plug flow system corresponding to the PCO device with a volume of VP = 5.6 × 10−3 m3. The PCO device was composed of a pleated photocatalytic filter (1100 cm2 and two 18-W UVA fluorescent tubes. The Clean Air Delivery Rate (CADR of the apparatus was measured under different operating conditions. The influence of three operating parameters was investigated: (i light irradiance I from 0.10 to 2.0 mW·cm−2; (ii air velocity v from 0.2 to 1.9 m·s−1; and (iii initial toluene concentration C0 (200, 600, 1000 and 4700 ppbv. The results showed that the conditions needed to apply a first-order decay model to the experimental data (described in Part I were fulfilled. The CADR values, ranging from 0.35 to 3.95 m3·h−1, were mainly dependent on the light irradiance intensity. A square root influence of the light irradiance was observed. Although the CADR of the PCO device inserted in the closed-loop reactor did not theoretically depend on the flow rate (see Part I, the experimental results did not enable the confirmation of this prediction. The initial concentration was also a parameter influencing the CADR, as well as the toluene degradation rate. The maximum degradation rate rmax ranged from 342 to 4894 ppbv/h. Finally, this study evidenced that a recirculation closed-loop pilot could be used to develop a reliable standard test method to assess the effectiveness of PCO devices.

  4. Thermal load determination in the mixing TEE impacted by a turbulent flow generated by two fluids at large gap of temperature

    International Nuclear Information System (INIS)

    Braillard, O.

    2005-01-01

    A 304L mixing tee mock-up is instrumented to assess the fluctuating temperature in the mixing area generated by two fluids (water) at large gap of temperature meet. The turbulent mixing layer impacts the structure wall and creates stresses, which lead to the damages. The case studied in this paper corresponds to the 'swinging streak' within a flow rate ratio of 25 %. The instrumentation is specifically planned to measure the fluctuating temperature in the fluid close to the internal skin and inside the wall too. This experiment is performed using a new sensor 'fluxmeter' which is non intrusive and typically designed to catch the fluctuation without any signal attenuation, within a frequency range 0-25Hz. The facility called 'Fatherino' supplies an available delta T of 70 degree C in water at 4 m/s mixture velocity in a mixing tee mock-up 50 mm in diameter. The flow features generate a large turbulent flow in the mixing layer and favour the heat flux transfer to the wall. By applying an inverse heat conduction method applied to the output data given by the fluxmeter, both the heat flux is deduced and the temperature (mean and fluctuating values) at the internal surface can be accurately determined. In addition, a calculation using the Trio U code (thermal hydraulic code) within the large eddy simulation module is computed to assess the fluid temperature distribution in the mixing area close to the internal surface. The output data in mean and standard deviation are compared with the Fatherino measurements. The comparison consists in analysing the main parameters as the mean and standard deviation in the fluid along the main axis and in a circumferential view. The mixing layer geometry and the frequency of the fluctuation are also analysed. These experiments added to the calculation allow us improving the state of the knowledge in the mixing tees and the thermal load to be used in the industrial mixing tees in operating for the long lifetime assessment or for the

  5. Determination of triazine herbicides and their metabolites in multiple medicinal parts of traditional Chinese medicines using streamlined pretreatment and UFLC-ESI-MS/MS.

    Science.gov (United States)

    Liu, Congmin; Dou, Xiaowen; Zhang, Lei; Li, Qian; Qin, Jia'an; Duan, Yaping; Yang, Meihua

    2018-01-01

    A rapid, sensitive, and reliable ultra-fast liquid chromatography combined with electrospray ionization tandem mass spectrometry (UFLC-ESI-MS/MS) method was established and applied to simultaneous determination of 31 triazine herbicides and their metabolites in multiple medicinal parts of traditional Chinese medicines (TCMs). A streamlined pretreatment approach using one-step extraction and dilution was proposed, which provided high-throughput processing, excellent recovery, and negligible interference. Afterwards, multiple-reaction monitoring (MRM) and information-dependent acquisition (IDA) triggered enhanced product ion spectra (EPI) was adopted to identify and quantify the targets in a single analysis. The optimized method was then validated according to the guidelines of the European Commission for the following parameters: Matrix effects, specificity, accuracy, precision, linearity, range, and stability. The LOD and LOQ for the 31 triazine herbicides were 0.1-10 μg kg -1 and 0.5-25 μg kg -1 , respectively. Recoveries at three concentration levels were within 67.9-120.3% with an associated precision RSD <20%. Using the proposed approach, trazines herbicides were determined from 44 commercially available TCMs. The detection rate of triazine herbicides residues was 15.9% of the total samples. Among them, atrazine, simeton, and simetryn were found in the radix, herba, and seed TCMs with values far below the referenced maximum residue limits (MRLs), but no residues were detected in either the flos or fructus. Taken together, this method has the potential to provide a means for triazines screening in extensive matrices, thereby laying the foundation for pesticide registration on TCMs. Moreover, it has the potential to guide further triazine residue control in TCMs. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Developmental and Subcellular Organization of Single-Cell C₄ Photosynthesis in Bienertia sinuspersici Determined by Large-Scale Proteomics and cDNA Assembly from 454 DNA Sequencing.

    Science.gov (United States)

    Offermann, Sascha; Friso, Giulia; Doroshenk, Kelly A; Sun, Qi; Sharpe, Richard M; Okita, Thomas W; Wimmer, Diana; Edwards, Gerald E; van Wijk, Klaas J

    2015-05-01

    Kranz C4 species strictly depend on separation of primary and secondary carbon fixation reactions in different cell types. In contrast, the single-cell C4 (SCC4) species Bienertia sinuspersici utilizes intracellular compartmentation including two physiologically and biochemically different chloroplast types; however, information on identity, localization, and induction of proteins required for this SCC4 system is currently very limited. In this study, we determined the distribution of photosynthesis-related proteins and the induction of the C4 system during development by label-free proteomics of subcellular fractions and leaves of different developmental stages. This was enabled by inferring a protein sequence database from 454 sequencing of Bienertia cDNAs. Large-scale proteome rearrangements were observed as C4 photosynthesis developed during leaf maturation. The proteomes of the two chloroplasts are different with differential accumulation of linear and cyclic electron transport components, primary and secondary carbon fixation reactions, and a triose-phosphate shuttle that is shared between the two chloroplast types. This differential protein distribution pattern suggests the presence of a mRNA or protein-sorting mechanism for nuclear-encoded, chloroplast-targeted proteins in SCC4 species. The combined information was used to provide a comprehensive model for NAD-ME type carbon fixation in SCC4 species.

  7. Optimum method to determine radioactivity in large tracts of land. In-situ gamma spectroscopy or sampling followed by laboratory measurement

    International Nuclear Information System (INIS)

    Bronson, Frazier

    2008-01-01

    In the process of decommissioning contaminated facilities, and in the conduct of normal operations involving radioactive material, it is frequently required to show that large areas of land are not contaminated, or if contaminated that the amount is below an acceptable level. However, it is quite rare for the radioactivity in the soil to be uniformly distributed. Rather it is generally in a few isolated and probably unknown locations. One way to ascertain the status of the land concentration is to take soil samples for subsequent measurement in the laboratory. Another way is to use in-situ gamma spectroscopy. In both cases, the non-uniform distribution of radioactivity can greatly compromise the accuracy of the assay, and makes uncertainty estimates much more complicated than simple propagation of counting statistics. This paper examines the process of determining the best way to estimate the activity on the tract of land, and gives quantitative estimates of measurement uncertainty for various conditions of radioactivity. When the distribution of radioactivity in the soil is not homogeneous, the sampling uncertainty is likely to be larger than the in-situ measurement uncertainty. (author)

  8. Determination of tributyltin in environmental water matrices using stir bar sorptive extraction with in-situ derivatisation and large volume injection-gas chromatography-mass spectrometry.

    Science.gov (United States)

    Neng, N R; Santalla, R P; Nogueira, J M F

    2014-08-01

    Stir bar sorptive extraction with in-situ derivatization using sodium tetrahydridoborate (NaBH4) followed by liquid desorption and large volume injection-gas chromatography-mass spectrometry detection under the selected ion monitoring mode (SBSE(NaBH4)in-situ-LD/LVI-GC-MS(SIM)) was successfully developed for the determination of tributyltin (TBT) in environmental water matrices. NaBH4 proved to be an effective and easy in-situ speciation agent for TBT in aqueous media, allowing the formation of adducts with enough stability and suitable polarity for SBSE analysis. Assays performed on water samples spiked at the 10.0μg/L, yielded convenient recoveries (68.2±3.0%), showed good accuracy, suitable precision (RSD<9.0%), low detection limits (23ng/L) and excellent linear dynamic range (r(2)=0.9999) from 0.1 to 170.0µg/L, under optimized experimental conditions. By using the standard addition method, the application of the present methodology to real surface water samples allowed very good performance at the trace level. The proposed methodology proved to be a feasible alternative for routine quality control analysis, easy to implement, reliable and sensitive to monitor TBT in environmental water matrices. Copyright © 2014 Elsevier B.V. All rights reserved.

  9. Deeply bound 1s and 2p pionic states in 205Pb and determination of the s-wave part of the pion-nucleus interaction

    International Nuclear Information System (INIS)

    Geissel, H.; Gilg, H.; Gillitzer, A.

    2001-06-01

    We observed well separated 1s and 2p π - states in 205 Pb in the 206 Pb(d, 3 He) reaction at T d = 604.3 MeV. The binding energies and the widths determined are: B 1s = 6.768 ± 0.044 (stat) ± 0.041 (syst) MeV, Γ 1s = 0.778 -0.130 +0.150 (stat) ± 0.055 (syst) MeV, B 2p = 5.110 ± 0.015 (stat) ± 0.042 (syst) MeV, and Γ 2p = 0.371 ± 0.037 (stat) ± 0.048 (syst) MeV. They are used to deduce the real and imaginary strengths of the s-wave part of the pion-nucleus interaction, yielding 26.1 -1.5 +1.7 MeV as a pion mass shift in the center of 205 Pb. (orig.)

  10. Influence of turbulence on the drop growth in warm clouds, Part I: comparison of numerically and experimentally determined collision kernels

    Directory of Open Access Journals (Sweden)

    Christoph Siewert

    2014-09-01

    Full Text Available This study deals with the comparison of numerically and experimentally determined collision kernels of water drops in air turbulence. The numerical and experimental setups are matched as closely as possible. However, due to the individual numerical and experimental restrictions, it could not be avoided that the turbulent kinetic energy dissipation rate of the measurement and the simulations differ. Direct numerical simulations (DNS are performed resulting in a very large database concerning geometric collision kernels with 1470 individual entries. Based on this database a fit function for the turbulent enhancement of the collision kernel is developed. In the experiments, the collision rates of large drops (radius >7.5μm$> 7.5\\,\\text{\\textmu{}m}$ are measured. These collision rates are compared with the developed fit, evaluated at the measurement conditions. Since the total collision rates match well for all occurring dissipation rates the distribution information of the fit could be used to enhance the statistical reliability and for the first time an experimental collision kernel could be constructed. In addition to the collision rates, the drop size distributions at three consecutive streamwise positions are measured. The drop size distributions contain mainly small drops (radius <7.5μm$< 7.5\\,\\text{\\textmu{}m}$. The measured evolution of the drop size distribution is confronted with model calculations based on the newly derived fit of the collision kernel. It turns out that the observed fast evolution of the drop size distribution can only be modeled if the collision kernel for small drops is drastically increased. A physical argument for this amplification is missing since for such small drops, neither DNSs nor experiments have been performed. For large drops, for which a good agreement of the collision rates was found in the DNS and the experiment, the time for the evolution of the spectrum in the wind tunnel is too short to draw

  11. Reanalysis of multi-temporal aerial images of Storglaciären, Sweden (1959–99 – Part 1: Determination of length, area, and volume changes

    Directory of Open Access Journals (Sweden)

    W. Haeberli

    2010-09-01

    Full Text Available Storglaciären, located in the Kebnekaise massif in northern Sweden, has a long history of glaciological research. Early photo documentations date back to the late 19th century. Measurements of front position variations and distributed mass balance have been carried out since 1910 and 1945/46, respectively. In addition to these in-situ measurements, aerial photographs have been taken at decadal intervals since the beginning of the mass balance monitoring program and were used to produce topographic glacier maps. Inaccuracies in the maps were a challenge to early attempts to derive glacier volume changes and resulted in major differences when compared to the direct glaciological mass balances. In this study, we reanalyzed dia-positives of the original aerial photographs of 1959, -69, -80, -90 and -99 based on consistent photogrammetric processing. From the resulting digital elevation models and orthophotos, changes in length, area, and volume of Storglaciären were computed between the survey years, including an assessment of related errors. Between 1959 and 1999, Storglaciären lost an ice volume of 19×106 m3, which corresponds to a cumulative ice thickness loss of 5.69 m and a mean annual loss of 0.14 m. This ice loss resulted largely from a strong volume loss during the period 1959–80 and was partly compensated during the period 1980–99. As a consequence, the glacier shows a strong retreat in the 1960s, a slowing in the 1970s, and pseudo-stationary conditions in the 1980s and 1990s.

  12. Determination of arsenic in ambient water at sub-part-per-trillion levels by hydride generation Pd coated platform collection and GFAAS detection.

    Science.gov (United States)

    Liang, L; Lazoff, S; Chan, C; Horvat, M; Woods, J S

    1998-11-01

    A method for trace determination of total arsenic in ambient waters is described. Arsenic is separated on-line from a large volume water sample by hydride generation and purging, pre-collected on a Pd coated pyrolytic platform cuvette using a simple and inexpensive system, and finally detected by GFAAS. Instrument parameters, hydride generation, transportation, and collection were optimized. The analytical behavior for major species including As(3+), As(5+), monomethyl As (MMA), and dimethyl As (DMA) were investigated individually. Problems arising from use of the system were discussed and eliminated. The necessity of sample digestion and an efficient digestion method were studied. Sample digestion for water with low organic content such as tap water and clean ground water and some clean surface water can be omitted. The method detection limit (MDL) is 0.3 ng l(-1) for a 25 ml water sample. Recoveries close to 100% with R.S.D.rain, sewage effluent, and saline water from different origins in the US, China, and Canada were collected and analyzed using ultra clean sampling and analysis techniques. The background levels of As in most water analyzed were established for the first time, and found to be far above the EPA's health effect criteria, 18 ng l(-1).

  13. X and gamma reference radiation for calibrating dosemeters and doserate meters and for determining their response as a function of photon energy - Part 4: Calibration of area and personal dosemeters in low energy X reference radiation fields

    International Nuclear Information System (INIS)

    2004-01-01

    ISO 4037 consists of the following parts, under the general title X and gamma reference radiation for calibrating dosemeters and doserate meters and for determining their response as a function of photon energy: Part 1: Radiation characteristics and production methods; Part 2: Dosimetry for radiation protection over the energy ranges from 8 keV to 1,3 MeV and 4 MeV to 9 MeV; Part 3: Calibration of area and personal dosemeters and the measurement of their response as a function of energy and angle of incidence; Part 4: Calibration of area and personal dosemeters in low energy X reference radiation fields. This part 4. of ISO 4037 gives guidelines on additional aspects of the characterization of low energy photon radiations. This part of ISO 4037 also describes procedures for calibration and determination of the response of area and personal dose(rate)meters as a function of photon energy and angle of incidence. This part of ISO 4037 concentrates on the accurate determination of conversion coefficients from air kerma to Hp(10) and H*(10) for the spectra of low energy photon radiations. As an alternative to the use of conversion coefficients, the direct calibration in terms of these quantities by means of appropriate reference instruments is described

  14. Development of a large-scale HPLC-based purification for the urease from Staphylococcus leei and determination of subunit structure.

    Science.gov (United States)

    Jin, Ming; Rosario, Wildys; Watler, Elsie; Calhoun, David H

    2004-03-01

    Coagulase-positive Staphylococcus species, related to but distinct from the genetic homology group containing Staphylococcus cohnii, Staphylococcus xylosus, and Staphylococcus saphrophyticus, were isolated from biopsy material obtained from a cluster of patients in Korea suffering from gastritis. The prototype isolate, Staphylococcus leei, has high urease activity that is similar with respect to a low K(m) value and acid resistance of the urease found in the stomach adapted pathogen, Helicobacter pylori. S. leei is remarkably resistant to lysis and only a small fraction of the cells are broken using sonication, a French press, Niro homogenizer, or a Gaulin mill. In the present report, we describe an efficient cell lysis procedure for S. leei using three passes through a Dynomill with 0.5mm glass beads that results in lysis of more than 95% of the cells. We also developed an efficient and large-scale purification procedure for the S. leei urease using a BioCAD HPLC Workstation using Q-Sepharose, Poros HP2, Sephacryl S-300, and hydroxyapatite chromatography. The urease of S. leei was purified 98-fold to a specific activity of 731U/mg. The urease protein is composed of three subunits, alpha (65kDa), beta (21kDa), and gamma (12kDa), and in situ enzyme assay and molecular sieve chromatography indicate that multiple high molecular weight forms are present, including an apparent pentamer of 1:1:1 alphabetagamma-heterotrimers of 480kDa. This purification procedure was used to purify 16mg of enzyme from 120-liters of cell culture. This improved lysis and purification procedure will make it possible to obtain sufficient quantities of urease for use as an antigen in ELISA assays to carry out studies to determine the incidence and demographic prevalence of gastritis due to S. leei.

  15. Spatial variation in foraging behaviour of a marine top predator (Phoca vitulina determined by a large-scale satellite tagging program.

    Directory of Open Access Journals (Sweden)

    Ruth J Sharples

    Full Text Available The harbour seal (Phoca vitulina is a widespread marine predator in Northern Hemisphere waters. British populations have been subject to rapid declines in recent years. Food supply or inter-specific competition may be implicated but basic ecological data are lacking and there are few studies of harbour seal foraging distribution and habits. In this study, satellite tagging conducted at the major seal haul outs around the British Isles showed both that seal movements were highly variable among individuals and that foraging strategy appears to be specialized within particular regions. We investigated whether these apparent differences could be explained by individual level factors: by modelling measures of trip duration and distance travelled as a function of size, sex and body condition. However, these were not found to be good predictors of foraging trip duration or distance, which instead was best predicted by tagging region, time of year and inter-trip duration. Therefore, we propose that local habitat conditions and the constraints they impose are the major determinants of foraging movements. Specifically the distance to profitable feeding grounds from suitable haul-out locations may dictate foraging strategy and behaviour. Accounting for proximity to productive foraging resources is likely to be an important component of understanding population processes. Despite more extensive offshore movements than expected, there was also marked fidelity to the local haul-out region with limited connectivity between study regions. These empirical observations of regional exchange at short time scales demonstrates the value of large scale electronic tagging programs for robust characterization of at-sea foraging behaviour at a wide spatial scale.

  16. COMPANY SIZE, TRADING ACTIVITY AND LIQUIDITY AS A DETERMINANTS OF CROSS-SECTIONAL MOMENTUM TRADING STRATEGY ON RUSSIAN STOCK MARKET. PART 2

    Directory of Open Access Journals (Sweden)

    Teplova T. V.

    2014-09-01

    Full Text Available Momentum-effect has many interpretations in the practice of investing and in understanding of anomalies in asset prices. We consider a Cross-Sectional momentum effects and the corresponding two medium-term (3 months or more trading strategies that are different from the trend following rules for individual assets. We tested four hypothesis deals with cross-sectional momentum effect on the Russian stock market and the possibility of building a self-financing (long-short trading strategy at three time horizon (stock market growth from 2004 until mid-2008, financial crisis and post-crisis periods. It is shown that for the Russian market cross-sectional momentum strategy with partly rebalanced portfolio maximizing portfolio return (134 stocks listed from 2004 to 2014 in the few Russian stock exchanges should be based on the three-month formation period and three-month holding period periods (3/1/3. We have identified elements of profit-maximizing momentum strategy: three time windows and determinants of assets. Monthly average return of arbitrage strategy is estimated at 1.5 % for 134 common shares. Implementation of the strategy for the post-crisis period does not allow to maximize profit. For 6 month and more investment windows it gets the advantage of reverse strategy (opening long positions in stocks with low investment results and short position for assets with high relative returns. Fundamental parameters of the issuer (size of companies like market capitalization and two measures of liquidity (trading activity and transaction costs like bid-ask spread are significant to maximize portfolio performance (we prove the growth of monthly average return ranging from 1.5 to 2.5 %. We find that size and liquidity control momentum strategy can earn positive profits in Russian stock market, larger than naïve momentum.

  17. 40 CFR Appendix Q to Part 50 - Reference Method for the Determination of Lead in Particulate Matter as PM10 Collected From...

    Science.gov (United States)

    2010-07-01

    ....5Quality assurance (QA) procedures for the collection of monitoring data are contained in Part 58, Appendix... set forth in Appendix A of part 58. The bias is assessed through an audit using spiked filters. The... Particulate Matter,” in Advances in X-Ray Analysis, J.R. Rhodes, Ed., Plenum Publishing Corporation, New York...

  18. Elimination of N,O-bis(trimethylsilyl)trifluoroacetamide interference by base treatment in derivatization gas chromatography mass spectrometry determination of parts per billion of alcohols in a food additive.

    Science.gov (United States)

    Zhu, Koudi; Gu, Binghe; Kerry, Michael; Mintert, Markus; Luong, Jim; Pursch, Matthias

    2017-03-24

    A novel base treatment followed by liquid-liquid extraction was developed to remove the interference of excess derivatization reagent BSTFA [N,O-Bis(trimethylsilyl)trifluoroacetamide] and its byproducts for trace determination of 1-chloro-2-propanol and 2-chloro-1-propanol in a food additive. The corresponding trimethylsilyl derivatives were analyzed by gas chromatography mass spectrometry (GC/MS) detection in selective ion monitoring mode. Due to a large volume splitless injection needed for achieving the required sensitivity, excess BSTFA in the derivatization sample solution interfered with the trimethylsilyl derivatives of the analytes of interest, making their quantitation not attainable. Efforts were made to decompose BSTFA while keeping the trimethylsilyl derivatives intact. Water or aqueous sulfuric acid treatment converted BSTFA into mainly N-trimethylsilyltrifluoroacetamide, which partitions between aqueous and organic layers. In contrast, aqueous sodium hydroxide decomposed BSTFA into trifluoroacetic acid, which went entirely into the aqueous layer. No BSTFA or its byproduct N-trimethylsilyltrifluoroacetamide or trifluroacetamide was found in the organic layer where the derivatized alcohols existed, which in turn completely eliminated their interference, enabling accurate and precise determination of parts per billion of the short-chain alcohols in the food additive. Contrary to the conventional wisdom that a trimethylsilyl derivative is susceptible to hydrolysis, the derivatized short-chain alcohols were found stable even in the presence of 0.17N aqueous sodium hydroxide as the improved GC/MS method was validated successfully, with a satisfactory linearity response in the concentration range of 10-400ng/g (regression coefficient greater than 0.999), good method precision (<4%), good recovery (90-98%), and excellent limit of detection (3ng/g) and limit of quantitation (10ng/g). Copyright © 2017 Elsevier B.V. All rights reserved.

  19. Large electrostatic accelerators

    International Nuclear Information System (INIS)

    Jones, C.M.

    1984-01-01

    The paper is divided into four parts: a discussion of the motivation for the construction of large electrostatic accelerators, a description and discussion of several large electrostatic accelerators which have been recently completed or are under construction, a description of several recent innovations which may be expected to improve the performance of large electrostatic accelerators in the future, and a description of an innovative new large electrostatic accelerator whose construction is scheduled to begin next year

  20. Determining Whether a Definitive Causal Relationship Exists Between Aripiprazole and Tardive Dyskinesia and/or Dystonia in Patients With Major Depressive Disorder, Part 3: Clinical Trial Data.

    Science.gov (United States)

    Preskorn, Sheldon H; Macaluso, Matthew

    2016-03-01

    three, 14-week studies involving 1088 subjects, 409 of whom were elderly like the 76-year-old individual presented in the case in the first column of this series. Finally, 3 short-term studies evaluated the use of aripiprazole in patients with psychosis associated with Alzheimer disease, a population who would be considered a relatively higher risk group for developing TD when exposed to antipsychotics and that also closely matches the patient in the case presented at the beginning of this series in terms of age. No incidence of TD was reported in this sample and mean scores on the Abnormal Involuntary Movement Scale decreased in individuals exposed to aripiprazole compared with those on placebo. On the basis of results of this review and data from registration trials of aripiprazole for all indications, the potential (or raw) incidence of what was termed TD occurred at rates ranging from 0.004 (4/987) based on long-term safety data from the program investigating aripiprazole augmentation treatment in MDD, to 0.0016 (19/11,897) based on the total safety database from aripiprazole registration trials for all indications, to 0 in trials in elderly individuals with Alzheimer disease. The confidence intervals for all of these potential incidence rates overlap with zero. The next column in this 5-part series reviews 37 case reports that reported TD in association with aripiprazole treatment and 27 case reports that suggested an improvement in preexisting TD with aripiprazole treatment. The fifth and final column in this series will discuss the types of prohibitively expensive and logistically difficult studies that would be needed to determine whether a definitive causal relationship between aripiprazole and TD exists.

  1. Determination of area averaged water vapour fluxes with large aperture and radio wave scintillometers over a heterogeneous surface - Flevoland field experiment

    NARCIS (Netherlands)

    Meijninger, W.M.L.; Green, A.E.; Hartogensis, O.K.; Kohsiek, W.; Hoedjes, J.C.B.; Zuurbier, R.M.; DeBruin, H.A.R.

    2002-01-01

    A large aperture scintillometer (LAS) and radio wave scintillometer (RWS) were installed over a heterogeneous area to test the applicability of the scintillation method. The heterogeneity in the area, which consisted of many plots, was mainly caused by differences in thermal properties of the crops;

  2. 40 CFR Appendix L to Part 50 - Reference Method for the Determination of Fine Particulate Matter as PM2.5 in the Atmosphere

    Science.gov (United States)

    2010-07-01

    ... and 1000 W/m2 solar radiation intensity. 7.4.8.2 The ambient temperature sensor shall be of such a... measurement of the mass concentration of fine particulate matter having an aerodynamic diameter less than or... matter specified in § 50.7 and § 50.13 of this part are met. The measurement process is considered to be...

  3. Large Pelagics Biological Survey

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Large Pelagics Biological Survey (LPBS) collects additional length and weight information and body parts such as otoliths, caudal vertebrae, dorsal spines, and...

  4. On the determination of the carrier concentration in large-grain polycrystalline InP, GaAs, and GaP by Hall effect measurements

    International Nuclear Information System (INIS)

    Siegel, W.; Kuehnel, G.; Schneider, H.A.

    1985-01-01

    Hall and conductivity measurements are performed in a wide temperature region on large-grain polycrystalline samples of n-InP, n- and p-GaAs as well as n- and p-GaP. The feasibility of Hall measurements at a given temperature depends mainly on the height PHI/sub B/ of the grain boundary potential barriers and on the average grain size. Measurements at room temperature are possible on large-grain material (average grain size 0.2 to 1 mm) for PHI/sub B/ <= 0.4 eV. For greater barrier heights elevated temperatures are necessary. If the Hall coefficient is measurable than it yields an effective carrier concentration for the polycrystalline sample which agrees well with the carrier concentration in the bulk of the grains. (author)

  5. High microvessel density determines a poor outcome in patients with diffuse large B-cell lymphoma treated with rituximab plus chemotherapy

    Science.gov (United States)

    Cardesa-Salzmann, Teresa M.; Colomo, Luis; Gutierrez, Gonzalo; Chan, Wing C.; Weisenburger, Dennis; Climent, Fina; González-Barca, Eva; Mercadal, Santiago; Arenillas, Leonor; Serrano, Sergio; Tubbs, Ray; Delabie, Jan; Gascoyne, Randy D.; Connors, Joseph M; Mate, Jose L.; Rimsza, Lisa; Braziel, Rita; Rosenwald, Andreas; Lenz, Georg; Wright, George; Jaffe, Elaine S.; Staudt, Louis; Jares, Pedro; López-Guillermo, Armando; Campo, Elias

    2011-01-01

    Background Diffuse large B-cell lymphoma is a clinically and molecularly heterogeneous disease. Gene expression profiling studies have shown that the tumor microenvironment affects survival and that the angiogenesis-related signature is prognostically unfavorable. The contribution of histopathological microvessel density to survival in diffuse large B-cell lymphomas treated with immunochemotherapy remains unknown. The purpose of this study is to assess the prognostic impact of histopathological microvessel density in two independent series of patients with diffuse large B-cell lymphoma treated with immunochemotherapy. Design and Methods One hundred and forty-seven patients from the Leukemia Lymphoma Molecular Profiling Project (training series) and 118 patients from the Catalan Lymphoma-Study group-GELCAB (validation cohort) were included in the study. Microvessels were immunostained with CD31 and quantified with a computerized image analysis system. The stromal scores previously defined in 110 Leukemia Lymphoma Molecular Profiling Project cases were used to analyze correlations with microvessel density data. Results Microvessel density significantly correlated with the stromal score (r=0.3209; P<0.001). Patients with high microvessel density showed significantly poorer overall survival than those with low microvessel density both in the training series (4-year OS 54% vs. 78%; P=0.004) and in the validation cohort (57% vs. 81%; P=0.006). In multivariate analysis, in both groups high microvessel density was a statistically significant unfavorable prognostic factor independent of international prognostic index [training series: international prognostic index (relative risk 2.7; P=0.003); microvessel density (relative risk 1.96; P=0.002); validation cohort: international prognostic index (relative risk 4.74; P<0.001); microvessel density (relative risk 2.4; P=0.016)]. Conclusions These findings highlight the impact of angiogenesis in the outcome of patients with

  6. Atomic absorption spectrophotometric determination of microgram levels of Co, Ni, Cu, Pb, and Zn in soil and sediment extracts containing large amounts of Mn and Fe

    Science.gov (United States)

    Chao, T.T.; Sanzolone, R.F.

    1973-01-01

    An atomic absorption spectrophotometric method has been developed for the determination of seven metal ions in the hydroxylamine extract of soils and sediments. Mn, Fe, and Zn are directly determined in the aqueous extract upon dilution. Co, Ni, Cu, and Pb in a separate aliquot of the extract are chelated with APDC (ammonium pyrrolidine dithiocarbamate) and extracted into MIBK (methyl isobutyl ketone) before determination. Data are presented to show the quantitative recovery of microgram levels of Co, Ni, Cu, and Pb by APDC-MIBK chelation-extraction from synthetic solutions containing as much as 2,000 ug/ml (micrograms per milliliter) Mn or 50 ug/ml Fe. Recovery of known amounts of the metal ions from sample solutions is equally satisfactory. Reproducible results are obtained by replicate analyses of two sediment samples for the seven metals.

  7. Comparative study of trusses to determine the influence of the geometry in the structural efficiency, according to the directions of the principal stresses : Part II

    OpenAIRE

    Señís, Roger; Brufau, Robert; Sastre, Ramón; Carbajal, Eusebio Carlos

    2015-01-01

    Congreso celebrado en la Escuela de Arquitectura de la Universidad de Sevilla desde el 24 hasta el 26 de junio de 2015. This study compares flat lattice girders mounted on two supports, based on various design parameters, to determine which have better structural performance and what geometries are more efficient. The fundamental goal is to determine the relationship of performance and structural behaviour of each type of framework structure, with respect to the principle of optimization a...

  8. Determining Clinically Relevant Changes in Community Walking Metrics to Be Tracked by the VA as Part of Routine Care in Lower Limb Amputee Veterans

    Science.gov (United States)

    2017-10-01

    Relevant Changes in Community Walking Metrics to Be Tracked by the VA as Part of Routine Care in Lower Limb Amputee Veterans 5c. PROGRAM ELEMENT ... poster presentation at the Association of Academic Physiatrists annual conference in Las Vegas. They are receiving value research and technical...writing experience. How were the results disseminated to communities of interest? A poster presentation was presented at the Association of Academic

  9. Shunt resistance and saturation current determination in CdTe and CIGS solar cells. Part 2: application to experimental IV measurements and comparison with other methods

    Science.gov (United States)

    Rangel-Kuoppa, Victor-Tapio; Albor-Aguilera, María-de-Lourdes; Hérnandez-Vásquez, César; Flores-Márquez, José-Manuel; Jiménez-Olarte, Daniel; Sastré-Hernández, Jorge; González-Trujillo, Miguel-Ángel; Contreras-Puente, Gerardo-Silverio

    2018-04-01

    In this Part 2 of this series of articles, the procedure proposed in Part 1, namely a new parameter extraction technique of the shunt resistance (R sh ) and saturation current (I sat ) of a current-voltage (I-V) measurement of a solar cell, within the one-diode model, is applied to CdS-CdTe and CIGS-CdS solar cells. First, the Cheung method is used to obtain the series resistance (R s ) and the ideality factor n. Afterwards, procedures A and B proposed in Part 1 are used to obtain R sh and I sat . The procedure is compared with two other commonly used procedures. Better accuracy on the simulated I-V curves used with the parameters extracted by our method is obtained. Also, the integral percentage errors from the simulated I-V curves using the method proposed in this study are one order of magnitude smaller compared with the integral percentage errors using the other two methods.

  10. Shunt resistance and saturation current determination in CdTe and CIGS solar cells. Part 1: a new theoretical procedure and comparison with other methodologies

    Science.gov (United States)

    Rangel-Kuoppa, Victor-Tapio; Albor-Aguilera, María-de-Lourdes; Hérnandez-Vásquez, César; Flores-Márquez, José-Manuel; González-Trujillo, Miguel-Ángel; Contreras-Puente, Gerardo-Silverio

    2018-04-01

    A new proposal for the extraction of the shunt resistance (R sh ) and saturation current (I sat ) of a current-voltage (I-V) measurement of a solar cell, within the one-diode model, is given. First, the Cheung method is extended to obtain the series resistance (R s ), the ideality factor (n) and an upper limit for I sat . In this article which is Part 1 of two parts, two procedures are proposed to obtain fitting values for R sh and I sat within some voltage range. These two procedures are used in two simulated I-V curves (one in darkness and the other one under illumination) to recover the known solar cell parameters R sh , R s , n, I sat and the light current I lig and test its accuracy. The method is compared with two different common parameter extraction methods. These three procedures are used and compared in Part 2 in the I-V curves of CdS-CdTe and CIGS-CdS solar cells.

  11. High-Resolution Nuclear Magnetic Resonance Determination of Transfer RNA Tertiary Base Pairs in Solution. 2. Species Containing a Large Variable Loop

    NARCIS (Netherlands)

    HURD, RE; ROBILLARD, GT; REID, BR

    1977-01-01

    The number of base pairs in the solution structure of several class III D3VN tRNA species from E. coli has been determined by analyzing the number of low-field (-15 to -11 ppm) proton resonances in their nuclear magnetic resonance spectra at 360 MHz. Contrary to previous reports indicating the

  12. Determination of the sulfur mustard hydrolysis product thiodiglycol by microcolumn liquid chromatography coupled on-line with sulfur flame photometric detection using large-volume injections and peak

    NARCIS (Netherlands)

    Hooijschuur, E.W.J.; Kientz, C.E.; Brinkman, U.A.T.

    1999-01-01

    A selective, direct and relatively rapid method has been developed for the determination of thiodiglycol (TDG) in aqueous samples. TDG is the main hydrolysis product of the chemical warfare agent sulfur mustard. The method of analysis is based on the on-line coupling of reversed-phase microcolumn

  13. Community air monitoring for pesticides-part 2: multiresidue determination of pesticides in air by gas chromatography, gas chromatography-mass spectrometry, and liquid chromatography-mass spectrometry.

    Science.gov (United States)

    Hengel, Matt; Lee, P

    2014-03-01

    Two multiresidue methods were developed to determine pesticides in air collected in California. Pesticides were trapped using XAD-4 resin and extracted with ethyl acetate. Based on an analytical method from the University of California Davis Trace Analytical Laboratory, pesticides were detected by analyzing the extract by gas chromatography-mass spectrometry (GC-MS) to determine chlorothalonil, chlorthal-dimethyl, cycloate, dicloran, dicofol, EPTC, ethalfluralin, iprodione, mefenoxam, metolachlor, PCNB, permethrin, pronamide, simazine, trifluralin, and vinclozolin. A GC with a flame photometric detector was used to determine chlorpyrifos, chlorpyrifos oxon, diazinon, diazinon oxon, dimethoate, dimethoate oxon, fonophos, fonophos oxon, malathion, malathion oxon, naled, and oxydemeton. Trapping efficiencies ranged from 78 to 92 % for low level (0.5 μg) and 37-104 % for high level (50 and 100 μg) recoveries. Little to no degradation of compounds occurred over 31 days; recoveries ranged from 78 to 113 %. In the California Department of Food and Agriculture (CDFA) method, pesticides were detected by analyzing the extract by GC-MS to determine chlorothalonil, chlorpyrifos, cypermethrin, dichlorvos, dicofol, endosulfan 1, endosulfan sulfate, oxyfluorfen, permethrin, propargite, and trifluralin. A liquid chromatograph coupled to a MS was used to determine azinphos-methyl, chloropyrifos oxon, DEF, diazinon, diazinon oxon, dimethoate, dimethoate oxon, diuron, EPTC, malathion, malathion oxon, metolachlor, molinate, norflurazon, oryzalin, phosmet, propanil, simazine and thiobencarb. Trapping efficiencies for compounds determined by the CDFA method ranged from 10 to 113, 22 to 114, and 56 to 132 % for 10, 5, and 2 μg spikes, respectively. Storage tests yielded 70-170 % recovery for up to 28 days. These multiresidue methods represent flexible, sensitive, accurate, and cost-effective ways to determine residues of various pesticides in ambient air.

  14. Stochastic split determinant algorithms

    International Nuclear Information System (INIS)

    Horvatha, Ivan

    2000-01-01

    I propose a large class of stochastic Markov processes associated with probability distributions analogous to that of lattice gauge theory with dynamical fermions. The construction incorporates the idea of approximate spectral split of the determinant through local loop action, and the idea of treating the infrared part of the split through explicit diagonalizations. I suggest that exact algorithms of practical relevance might be based on Markov processes so constructed

  15. Determination of the physical values of a plasma puff by analysis of the diamagnetic signals. 1. part: expansion model for the puff. 2. part: comparison of experimental results with the expansion model for the plasma puff

    International Nuclear Information System (INIS)

    Jacquinot, J.; Leloup, Ch.; Waelbroeck, F.; Poffe, J.P.

    1964-01-01

    The flow of a dense plasma puff, along the axis of a uniform magnetic field is examined, assuming the following hypotheses: the axial distribution of the line density can be described at any time by a gaussian function whose characteristic parameter is independent of the distance from the axis of the system; the β ratio is less than 0,6. An approximate solution of the magnetohydrodynamics equations is obtained. The evolution of the characteristic properties of the plasma (local velocity, temperature and density) can be calculated from a set of equations involving 5 plasma parameters. A method leading to the determination of these parameters is described. It uses 5 informations picked up from the diamagnetic signals induced by the plasma into a set of 4 compensated magnetic loops. (authors) [fr

  16. Community health clinical education in Canada: part 2--developing competencies to address social justice, equity, and the social determinants of health.

    Science.gov (United States)

    Cohen, Benita E; Gregory, David

    2009-01-01

    Recently, several Canadian professional nursing associations have highlighted the expectations that community health nurses (CHNs) should address the social determinants of health and promote social justice and equity. These developments have important implications for (pre-licensure) CHN clinical education. This article reports the findings of a qualitative descriptive study that explored how baccalaureate nursing programs in Canada address the development of competencies related to social justice, equity, and the social determinants of health in their community health clinical courses. Focus group interviews were held with community health clinical course leaders in selected Canadian baccalaureate nursing programs. The findings foster understanding of key enablers and challenges when providing students with clinical opportunities to develop the CHN role related to social injustice, inequity, and the social determinants of health. The findings may also have implications for nursing programs internationally that are addressing these concepts in their community health clinical courses.

  17. Convective and large-scale mass flux profiles over tropical oceans determined from synergistic analysis of a suite of satellite observations

    Science.gov (United States)

    Masunaga, Hirohiko; Luo, Zhengzhao Johnny

    2016-07-01

    A new, satellite-based methodology is developed to evaluate convective mass flux and large-scale total mass flux. To derive the convective mass flux, candidate profiles of in-cloud vertical velocity are first constructed with a simple plume model under the constraint of ambient sounding and then narrowed down to the solution that matches satellite-derived cloud top buoyancy. Meanwhile, the large-scale total mass flux is provided separately from satellite soundings by a method developed previously. All satellite snapshots are sorted into a composite time series that delineates the evolution of a vigorous and organized convective system. Principal findings are the following. First, convective mass flux is modulated primarily by convective cloud cover, with the intensity of individual convection being less variable over time. Second, convective mass flux dominates the total mass flux only during the early hours of the convective evolution; as convective system matures, a residual mass flux builds up in the mass flux balance that is reminiscent of stratiform dynamics. The method developed in this study is expected to be of unique utility for future observational diagnosis of tropical convective dynamics and for evaluation of global climate model cumulus parameterizations in a global sense.

  18. The generalized centroid difference method for picosecond sensitive determination of lifetimes of nuclear excited states using large fast-timing arrays

    Energy Technology Data Exchange (ETDEWEB)

    Régis, J.-M., E-mail: regis@ikp.uni-koeln.de [Institut für Kernphysik der Universität zu Köln, Zülpicher Str. 77, 50937 Köln (Germany); Mach, H. [Departamento de Física Atómica y Nuclear, Universidad Complutense, 28040 Madrid (Spain); Simpson, G.S. [Laboratoire de Physique Subatomique et de Cosmologie Grenoble, 53, rue des Martyrs, 38026 Grenoble Cedex (France); Jolie, J.; Pascovici, G.; Saed-Samii, N.; Warr, N. [Institut für Kernphysik der Universität zu Köln, Zülpicher Str. 77, 50937 Köln (Germany); Bruce, A. [School of Computing, Engineering and Mathematics, University of Brighton, Lewes Road, Brighton BN2 4GJ (United Kingdom); Degenkolb, J. [Institut für Kernphysik der Universität zu Köln, Zülpicher Str. 77, 50937 Köln (Germany); Fraile, L.M. [Departamento de Física Atómica y Nuclear, Universidad Complutense, 28040 Madrid (Spain); Fransen, C. [Institut für Kernphysik der Universität zu Köln, Zülpicher Str. 77, 50937 Köln (Germany); Ghita, D.G. [Horia Hulubei National Institute for Physics and Nuclear Engineering, 77125 Bucharest (Romania); and others

    2013-10-21

    A novel method for direct electronic “fast-timing” lifetime measurements of nuclear excited states via γ–γ coincidences using an array equipped with N∈N equally shaped very fast high-resolution LaBr{sub 3}(Ce) scintillator detectors is presented. Analogous to the mirror symmetric centroid difference method, the generalized centroid difference method provides two independent “start” and “stop” time spectra obtained by a superposition of the N(N−1)γ–γ time difference spectra of the N detector fast-timing system. The two fast-timing array time spectra correspond to a forward and reverse gating of a specific γ–γ cascade. Provided that the energy response and the electronic time pick-off of the detectors are almost equal, a mean prompt response difference between start and stop events is calibrated and used as a single correction for lifetime determination. These combined fast-timing arrays mean γ–γ time-walk characteristics can be determined for 40keVdetermination limit of the method over the total dynamic range is mainly determined by the statistics. The setup of an N=4 detector fast-timing array delivered an absolute time resolving power of 3 ps for 10 000 γ–γ events per total fast timing array start and stop time spectrum. The new method is tested over the total dynamic range by the measurements of known picosecond lifetimes in standard γ-ray sources.

  19. Accuracy Of The Place Of Crimes Determination As A Factor Of The Structure Of Special Part Of The Criminal Code Of The Russian Federation Preservation

    Directory of Open Access Journals (Sweden)

    Inga V. Pantyuxina

    2014-06-01

    Full Text Available In the present article the problem of nonobservance of logical and legal means, receptions and rules of the separate structures of crimes in the structure of criminal law placement which breaks systemacity of the Special part on the Criminal Code of the Russian Federation is raised. Questions of crimes regulated in articles 138.1, 214, 226.1, 240 and 242.2 of the Criminal Code of the Russian Federation in the structure of the Special part of the Criminal Code of the Russian Federation is researched and analyzed. Researching their objects and a number of signs of the objective party, authors focus attention on the shift of priorities in these structures of crimes from the public relations regulated in them into the favor of less significant out of what the failure to place their criminal and legal material in the Special part of the Criminal Code of the Russian Federation. Discrepancy of objects in crimes regulated by articles 138.1 and 242.2 of the Criminal Code of the Russian Federation to the patrimonial and specific objects of the groups of crimes in which they are located in this connection, due to what it is offered to move them to other groups of crimes. Analysis of crimes structures regulated in the article 214, 226.1 and 240 of the Criminal Code of the Russian Federation led to the conclusion that is reasonable to allocate independent structures of crimes and to define other legal niches of the Criminal Code of the Russian Federation, other than those in which they are located.

  20. The Software Reliability of Large Scale Integration Circuit and Very Large Scale Integration Circuit

    OpenAIRE

    Artem Ganiyev; Jan Vitasek

    2010-01-01

    This article describes evaluation method of faultless function of large scale integration circuits (LSI) and very large scale integration circuits (VLSI). In the article there is a comparative analysis of factors which determine faultless of integrated circuits, analysis of already existing methods and model of faultless function evaluation of LSI and VLSI. The main part describes a proposed algorithm and program for analysis of fault rate in LSI and VLSI circuits.

  1. "A Degree Is a Part of the Puzzle, but Only a Piece." Understanding How Employers Determine the Value of Academic Credentials

    Science.gov (United States)

    Kaspari, Brenda Anderson

    2017-01-01

    With the skyrocketing costs of higher education and the increased scrutiny of how educational institutions prepare graduates for the workplace, this dissertation explored how the "outsiders," or employers, view and determine the value of academic credentials. Using the premise of credentialism, this grounded theory, qualitative study…

  2. Determination of telmisartan in human blood plasma: Part II: Liquid chromatography-tandem mass spectrometry method development, comparison to immunoassay and pharmacokinetic study

    NARCIS (Netherlands)

    Hempen, C.M.; Gläsle-Schwarz, Liane; Kunz, Ulrich; Karst, U.

    2006-01-01

    A new liquid chromatography/atmospheric pressure chemical ionization-tandem mass spectrometry (LC/APCI-MS/MS) method with on-line sample clean-up for the determination of telmisartan in human blood plasma is presented. This technique is compared to a previously introduced enzyme-linked immunosorbent

  3. The determination of the pressure-viscosity coefficient of a lubricant through an accurate film thickness formula and accurate film thickness measurements : part 2 : high L values

    NARCIS (Netherlands)

    Leeuwen, van H.J.

    2011-01-01

    The pressure-viscosity coefficient of a traction fluid is determined by fitting calculation results on accurate film thickness measurements, obtained at different speeds, loads, and temperatures. Through experiments, covering a range of 5.6

  4. Rotating electrical machines part 2 : methods for determining losses and efficiency of rotating electrical machinery form tests (excl. machines for traction vehicles)

    CERN Document Server

    International Electrotechnical Commission. Geneva

    1972-01-01

    Applies to d.c. machines and to a.c. synchronous and induction machines. The principles can be applied to other types of machines such as rotary converters, a.c. commutator motors and single-phase induction motors for which other methods of determining losses are used.

  5. Determination of plasma parameters from soft X-ray images for coronal holes /open magnetic field configurations/ and coronal large-scale structures /extended closed-field configurations/

    Science.gov (United States)

    Maxson, C. W.; Vaiana, G. S.

    1977-01-01

    In connection with high-quality solar soft X-ray images the 'quiet' features of the inner corona have been separated into two sharply different components, including the strongly reduced emission areas or coronal holes (CH) and the extended regions of looplike emission features or large-scale structures (LSS). Particular central meridian passage observations of the prominent CH1 on August 21, 1973, are selected for a quantitative study. Histogram photographic density distributions for full-disk images at other central meridian passages of CH 1 are also presented, and the techniques of converting low photographic density data to deposited energy are discussed, with particular emphasis on the problems associated with the CH data.

  6. Drell-Yan events from 400 GeV/c protons: Determination of the K-factor in a large kinematical domain

    International Nuclear Information System (INIS)

    Badier, J.; Bourotte, J.; Karyotakis, Y.; Mine, P.; Vanderhaghen, R.; Weisz, S.; Boucrot, J.; Callot, O.; Decamp, D.; Lefrancois, J.; Crozon, M.; Delpierre, P.; Leray, T.; Maillard, J.; Tilquin, A.

    1985-01-01

    We present the analysis of proportional30,000 high mass dimuons (Msub(μμ)>4.5 GeV/c 2 ) produced in 400 GeV/c proton-platinum interactions. A determination of the K-factor is given for different values of xsub(F) and Msub(μμ), and its variations are compared to QCD predictions. The proton structure functions derived from these events are compared to the values obtained in deep inelastic lepton scattering. (orig.)

  7. Preclinical endoscopic training using a part-task simulator: learning curve assessment and determination of threshold score for advancement to clinical endoscopy.

    Science.gov (United States)

    Jirapinyo, Pichamol; Abidi, Wasif M; Aihara, Hiroyuki; Zaki, Theodore; Tsay, Cynthia; Imaeda, Avlin B; Thompson, Christopher C

    2017-10-01

    Preclinical simulator training has the potential to decrease endoscopic procedure time and patient discomfort. This study aims to characterize the learning curve of endoscopic novices in a part-task simulator and propose a threshold score for advancement to initial clinical cases. Twenty novices with no prior endoscopic experience underwent repeated endoscopic simulator sessions using the part-task simulator. Simulator scores were collected; their inverse was averaged and fit to an exponential curve. The incremental improvement after each session was calculated. Plateau was defined as the session after which incremental improvement in simulator score model was less than 5%. Additionally, all participants filled out questionnaires regarding simulator experience after sessions 1, 5, 10, 15, and 20. A visual analog scale and NASA task load index were used to assess levels of comfort and demand. Twenty novices underwent 400 simulator sessions. Mean simulator scores at sessions 1, 5, 10, 15, and 20 were 78.5 ± 5.95, 176.5 ± 17.7, 275.55 ± 23.56, 347 ± 26.49, and 441.11 ± 38.14. The best fit exponential model was [time/score] = 26.1 × [session #] -0.615 ; r 2  = 0.99. This corresponded to an incremental improvement in score of 35% after the first session, 22% after the second, 16% after the third and so on. Incremental improvement dropped below 5% after the 12th session corresponding to the predicted score of 265. Simulator training was related to higher comfort maneuvering an endoscope and increased readiness for supervised clinical endoscopy, both plateauing between sessions 10 and 15. Mental demand, physical demand, and frustration levels decreased with increased simulator training. Preclinical training using an endoscopic part-task simulator appears to increase comfort level and decrease mental and physical demand associated with endoscopy. Based on a rigorous model, we recommend that novices complete a minimum of 12 training

  8. Genetic method of combating the cabbage root fly. Part II. Localization of factor determining male sex in the cabbage root fly Delia brassicae bouche

    International Nuclear Information System (INIS)

    Samoilov, Yu.B.

    1986-01-01

    Cytogenetic analysis was conducted of 15 lines of the cabbage root fly with hereditary semisterility in the form of late embryonic lethals (LEL). In 14 lines (93%), the presence of translocations was noted. A high yield of translocations linked with the male sex was obtained, which was caused by the fact that determination of male sex in this species is apparently associated with the largest chromosome 6, and not with chromosome 1, as was believed previously

  9. Determination of levels of polychlorinated biphenyl in transformers oil from some selected transformers in parts of the Greater Accra Region of Ghana.

    Science.gov (United States)

    Buah-Kwofie, Archibold; Yeboah, Philip O; Pwamang, John

    2011-01-01

    Although polychlorinated biphenyls have never been manufactured in Ghana, it has been used extensively as dielectric fluid in electric transformers and capacitors. However, very little is known of its health and environmental impacts by both managers of these transformers and capacitors and also the general public. This work therefore seeks to explore INAA as a possible alternative to screening transformer oils for PCBs by determining the total chlorine content. The total chlorine content of transformer oil samples from Ghana that tested positive and some randomly selected samples that tested negative from screening using CLOR-N-OIL test kits, have had their total chlorine estimated. INAA using the Research Reactor located at the Ghana Atomic Energy Commission was used to estimate the total chlorine content of the oil samples. Neutron Activation and gamma ray spectroscopy using HPGe detector coupled to MAESTRO 32 software was used to determine the total chlorine content by integrating the peak area of the spectrum into a simplified program that was developed from the activation equation. Instrumental Neutron Activation Analysis was able to validate the result obtained from the test kits screening with accuracy 7.5%. The minimum total chlorine content of the positive samples determined by NAA was 71.34 μg g⁻¹. Copyright © 2010 Elsevier Ltd. All rights reserved.

  10. Determination of selected quaternary ammonium compounds by liquid chromatography with mass spectrometry. Part II. Application to sediment and sludge samples in Austria

    International Nuclear Information System (INIS)

    Martinez-Carballo, Elena; Gonzalez-Barreiro, Carmen; Sitka, Andrea; Kreuzinger, Norbert; Scharf, Sigrid; Gans, Oliver

    2007-01-01

    Soxhlet extraction and high-performance liquid chromatography (HPLC) coupled to tandem mass spectrometry detection (MS/MS) was used for the determination of selected quaternary ammonium compounds (QACs) in solid samples. The method was applied for the determination of alkyl benzyl, dialkyl and trialkyl quaternary ammonium compounds in sediment and sludge samples in Austria. The overall method quantification limits range from 0.6 to 3 μg/kg for sediments and from 2 to 5 μg/kg for sewage sludges. Mean recoveries between 67% and 95% are achieved. In general sediments were especially contaminated by C12 chain benzalkonium chloride (BAC-C12) as well as by the long C-chain dialkyldimethylammonium chloride (DDAC-C18) with a maximum concentration of 3.6 mg/kg and 2.1 mg/kg, respectively. Maxima of 27 mg/kg for DDAC-C10, 25 mg/kg for BAC-C12 and 23 mg/kg for BAC-C14 were determined for sludge samples. The sums of the 12 selected target compounds range from 22 mg/kg to 103 mg/kg in the sludge samples. - The presence of quaternary ammonium surfactants in sediment and sludge samples is reported for the first time in Austria

  11. Infrared-faint radio sources are at high redshifts. Spectroscopic redshift determination of infrared-faint radio sources using the Very Large Telescope

    Science.gov (United States)

    Herzog, A.; Middelberg, E.; Norris, R. P.; Sharp, R.; Spitler, L. R.; Parker, Q. A.

    2014-07-01

    Context. Infrared-faint radio sources (IFRS) are characterised by relatively high radio flux densities and associated faint or even absent infrared and optical counterparts. The resulting extremely high radio-to-infrared flux density ratios up to several thousands were previously known only for high-redshift radio galaxies (HzRGs), suggesting a link between the two classes of object. However, the optical and infrared faintness of IFRS makes their study difficult. Prior to this work, no redshift was known for any IFRS in the Australia Telescope Large Area Survey (ATLAS) fields which would help to put IFRS in the context of other classes of object, especially of HzRGs. Aims: This work aims at measuring the first redshifts of IFRS in the ATLAS fields. Furthermore, we test the hypothesis that IFRS are similar to HzRGs, that they are higher-redshift or dust-obscured versions of these massive galaxies. Methods: A sample of IFRS was spectroscopically observed using the Focal Reducer and Low Dispersion Spectrograph 2 (FORS2) at the Very Large Telescope (VLT). The data were calibrated based on the Image Reduction and Analysis Facility (IRAF) and redshifts extracted from the final spectra, where possible. This information was then used to calculate rest-frame luminosities, and to perform the first spectral energy distribution modelling of IFRS based on redshifts. Results: We found redshifts of 1.84, 2.13, and 2.76, for three IFRS, confirming the suggested high-redshift character of this class of object. These redshifts and the resulting luminosities show IFRS to be similar to HzRGs, supporting our hypothesis. We found further evidence that fainter IFRS are at even higher redshifts. Conclusions: Considering the similarities between IFRS and HzRGs substantiated in this work, the detection of IFRS, which have a significantly higher sky density than HzRGs, increases the number of active galactic nuclei in the early universe and adds to the problems of explaining the formation of

  12. Determination of the variability of both hydrophilic and lipophilic toxins in endemic wild bivalves and carnivorous gastropods from the southern part of Chile.

    Science.gov (United States)

    Zamorano, Ruben; Marín, Michelle; Cabrera, Fabiola; Figueroa, Diego; Contreras, Cristóbal; Barriga, Andrés; Lagos, Néstor; García, Carlos

    2013-01-01

    The aim of this study was to analyse and determine the composition of paralytic shellfish poisoning (PSP) toxins and lipophilic toxins in the Region of Aysén, Chile, in wild endemic mussels (Mytilus chilensis, Venus antiqua, Aulacomya ater, Choromytilus chorus, Tagelus dombeii and Gari solida) and in two endemic carnivorous molluscs species (Concholepas concholepas and Argobuccinum ranelliforme). PSP-toxin contents were determined by using HPLC with fluorescence detection, while lipophilic toxins were determined by using LC-MS/MS. Mean concentrations for the total of PSP toxins were in the range 55-2505 μg saxitoxin-equivalent/100 g. The two most contaminated samples for PSP toxicity were bivalve Gari solida and carnivorous Argobuccinum ranelliforme with 2505 ± 101 and 1850 ± 137 μg saxitoxin-equivalent/100 g, respectively (p < 0.05). The lipophilic toxins identified were okadaic acid, dinophysistoxin-1 (DTX-1), azaspiracid-1 (AZA-1), pectenotoxin-2 (PTX-2) and yessotoxins (YTX). All analysed molluscs contained lipophilic toxins at levels ranging from 56 ± 4.8 to 156.1 ± 8.2 μg of okadaic acid-equivalent/kg shellfish together with YTX at levels ranging from 1.0 ± 0.1 to 18 ± 0.9 μg of YTX-equivalent/kg shellfish and AZA at levels ranging from 3.6 ± 0.2 to 31 ± 2.1 μg of AZA-equivalent/kg shellfish. Furthermore, different bivalves and gastropods differ in their capacity of retention of lipophilic toxins, as shown by the determination of their respective lipophilic toxins levels. In all the evaluated species, the presence of lipophilic toxins associated with biotransformation in molluscs and carnivorous gastropods was not identified, in contrast to the identification of PSP toxins, where the profiles identified in the different species are directly related to biotransformation processes. Thus, this study provides evidence that the concentration of toxins in the food intake of the evaluated species (Bivalvia and Gastropoda class) determines the degree of

  13. Rapid determination of environmental plutonium in large water samples by means of manganese dioxide Co-precipitation and extraction chromatographic separation

    International Nuclear Information System (INIS)

    Sidhu, R.S.; Hoff, P.

    1999-01-01

    Plutonium activity determinations in environmental water samples are routinely performed in many laboratories. Due to the low plutonium concentrations and the complexity of the plutonium aqueous chemistry, these analysis involve cumbersome preconcentration and separation procedures and long measurement times. We describe a procedure where MnO 2 (s) is used as scavenger to preconcentrate Pu prior to separation by the transuranium specific extraction chromatographic resin TRU-Resin. The ability of MnO 4 - /MnO 2 (s) to destroy organic matter and oxidise plutonium is combined with the specific behaviour of the TRU-resin for transuranium elements. The method facilitates a rapid preconcentration and separation of plutonium. With the use of this procedure, the laboratory work on one sample can be performed in one day with minimum attention. The overall yields from a 200 litre fresh- or seawater sample to a measurable Pu source are between 70-85%. (orig.)

  14. Determination of the neutron energy and spatial distributions of the neutron beam from the TSR-II in the large beam shield

    International Nuclear Information System (INIS)

    Clifford, C.E.; Muckenthaler, F.J.

    1976-01-01

    The TSR-II reactor of the ORNL Tower Shielding Facility has recently been relocated within a new, fixed shield. A principal feature of the new shield is a beam port of considerably larger area than that of its predecessor. The usable neutron flux has thereby been increased by a factor of approximately 200. The bare beam neutron spectrum behind the new shield has been experimentally determined over the energy range from 0.8 to 16 MeV. A high level of fission product gamma ray background prevented measurement of bare beam spectra below 0.8 MeV, however neutron spectra in the energy range from 8 keV to 1.4 MeV were obtained for two simple, calculable shielding configurations. Also measured in the present work were weighted integral flux distributions and fast neutron dose rates

  15. Determining optimal parameters of the self-referent encoding task: A large-scale examination of self-referent cognition and depression.

    Science.gov (United States)

    Dainer-Best, Justin; Lee, Hae Yeon; Shumake, Jason D; Yeager, David S; Beevers, Christopher G

    2018-06-07

    Although the self-referent encoding task (SRET) is commonly used to measure self-referent cognition in depression, many different SRET metrics can be obtained. The current study used best subsets regression with cross-validation and independent test samples to identify the SRET metrics most reliably associated with depression symptoms in three large samples: a college student sample (n = 572), a sample of adults from Amazon Mechanical Turk (n = 293), and an adolescent sample from a school field study (n = 408). Across all 3 samples, SRET metrics associated most strongly with depression severity included number of words endorsed as self-descriptive and rate of accumulation of information required to decide whether adjectives were self-descriptive (i.e., drift rate). These metrics had strong intratask and split-half reliability and high test-retest reliability across a 1-week period. Recall of SRET stimuli and traditional reaction time (RT) metrics were not robustly associated with depression severity. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  16. Host plant development, water level and water parameters shape Phragmites australis-associated oomycete communities and determine reed pathogen dynamics in a large lake.

    Science.gov (United States)

    Wielgoss, Anna; Nechwatal, Jan; Bogs, Carolin; Mendgen, Kurt

    2009-08-01

    In a 3-year-study, we analysed the population dynamics of the reed pathogen Pythium phragmitis and other reed-associated oomycetes colonizing fresh and dried reed leaves in the littoral zone of a large lake. Oomycete communities derived from internal transcribed spacer clone libraries were clearly differentiated according to substrate and seasonal influences. In fresh leaves, diverse communities consisting of P. phragmitis and other reed-associated pathogens were generally dominant. Pythium phragmitis populations peaked in spring with the emergence of young reed shoots, and in autumn after extreme flooding events. In summer it decreased with falling water levels, changing water chemistry and rising temperatures. Another Pythium species was also highly abundant in fresh leaves throughout the year and might represent a new, as-yet uncultured reed pathogen. In dried leaves, reed pathogens were rarely detected, whereas saprophytic species occurred abundantly during all seasons. Saprophyte communities were less diverse, less temperature sensitive and independent of reed development. In general, our results provide evidence for the occurrence of highly specialized sets of reed-associated oomycetes in a natural reed ecosystem. Quantitative analyses (clone abundances and quantitative real-time PCR) revealed that the reed pathogen P. phragmitis is particularly affected by changing water levels, water chemistry and the stage of reed development.

  17. The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1.

    Science.gov (United States)

    Heeren, Gino; Rinnerthaler, Mark; Laun, Peter; von Seyerl, Phyllis; Kössler, Sonja; Klinger, Harald; Hager, Matthias; Bogengruber, Edith; Jarolim, Stefanie; Simon-Nobbe, Birgit; Schüller, Christoph; Carmona-Gutierrez, Didac; Breitenbach-Koller, Lore; Mück, Christoph; Jansen-Dürr, Pidder; Criollo, Alfredo; Kroemer, Guido; Madeo, Frank; Breitenbach, Michael

    2009-07-13

    Yeast mother cell-specific aging constitutes a model of replicative aging as it occurs in stem cell populations of higher eukaryotes. Here, we present a new long-lived yeast deletion mutation,afo1 (for aging factor one), that confers a 60% increase in replicative lifespan. AFO1/MRPL25 codes for a protein that is contained in the large subunit of the mitochondrial ribosome. Double mutant experiments indicate that the longevity-increasing action of the afo1 mutation is independent of mitochondrial translation, yet involves the cytoplasmic Tor1p as well as the growth-controlling transcription factor Sfp1p. In their final cell cycle, the long-lived mutant cells do show the phenotypes of yeast apoptosis indicating that the longevity of the mutant is not caused by an inability to undergo programmed cell death. Furthermore, the afo1 mutation displays high resistance against oxidants. Despite the respiratory deficiency the mutant has paradoxical increase in growth rate compared to generic petite mutants. A comparison of the single and double mutant strains for afo1 and fob1 shows that the longevity phenotype of afo1 is independent of the formation of ERCs (ribosomal DNA minicircles). AFO1/MRPL25 function establishes a new connection between mitochondria, metabolism and aging.

  18. Large third-order nonlinearity of nonpolar A-plane GaN film at 800 nm determined by Z-scan technology

    Science.gov (United States)

    Zhang, Feng; Han, Xiangyun

    2014-09-01

    We report an investigation on the optical third-order nonlinear property of the nonpolar A-plane GaN film. The film sample with a thickness of ~2 μm was grown on an r-plane sapphire substrate by metal-organic chemical vapor deposition system. By performing the Z-scan method combined with a mode-locked femtosecond Ti:sapphire laser (800 nm, 50 fs), the optical nonlinearity of the nonpolar A-plane GaN film was measured with the electric vector E of the laser beam being polarized parallel (//) and perpendicular (⊥) to the c axis of the film. The results show that both the third-order nonlinear absorption coefficient β and the nonlinear refractive index n2 of the sample film possess negative and large values, i.e. β// = -135 ± 29 cm/GW, n2// = -(4.0 ± 0.3) × 10-3 cm2/GW and β⊥ = -234 ± 29 cm/GW, n2⊥ = -(4.9 ± 0.4) × 10-3 cm2/GW, which are much larger than those of conventional C-plane GaN film, GaN bulk, and even the other oxide semiconductors.

  19. Determination of the distribution of copper and chromium in partly remediated CCA-treated pine wood using SEM and EDX analyses

    DEFF Research Database (Denmark)

    Christensen, Iben Vernegren; Ottosen, Lisbeth M.; Melcher, Eckhard

    2005-01-01

    . After soaking, a small amount of Cu and Cr was still present in the cell walls but larger particles were now found on wall surfaces. Most effective removal of Cu was obtained after soaking in phosphoric and oxalic acid followed by EDR; here numerous rice grain-shaped particles were observed containing...... large amounts of Cu and no Cr. Cr was most effectively removed after soaking in oxalic acid and subsequent EDR treatment or dual soaking in phosphoric acid and oxalic acid with and without subsequent EDR.......Soaking in different acids and electrodialytic remediation (EDR) were applied for removing copper and chromium from freshly Chromated Copper Arsenate (CCA) impregnated EN 113 pine wood samples. After remedial treatments, AAS analyses revealed that the concentration of copper (Cu) and chromium (Cr...

  20. Determination of barium in natural waters by ICP-OES technique. Part II: Assessment of human exposure to barium in bottled mineral and spring waters produced in Poland.

    Science.gov (United States)

    Garboś, Sławomir; Swiecicka, Dorota

    2013-01-01

    A method of the classification of natural mineral and spring waters and maximum admissible concentration (MAC) levels of metals present in such types of waters are regulated by Commission Directive 2003/40/EC, Directive 2009/54/EC of the European Parliament and of the Council and Ordinance of Minister of Health of 30 March 2011 on the natural mineral waters, spring waters and potable waters. MAC of barium in natural mineral and spring waters was set at 1.0 mg/l, while World Health Organization determined the Ba guideline value in water intended for human consumption at the level of 0.7 mg/l. The aims of the study were: the determination of barium in natural mineral and spring waters (carbonated, non-carbonated and medium-carbonated waters) produced and bottled on the area of Poland, and assessment of human exposure to this metal presents in the above-mentioned types of waters. The study concerning barium determinations in 23 types of bottled natural mineral waters and 15 types of bottled spring waters (bought in Polish retail outlets) was conducted in 2010. The analyses were performed by validated method of determination of barium in water based on inductively coupled plasma optical emission spectrometry, using modern internal quality control scheme. Concentrations of barium determined in natural mineral and spring waters were in the ranges from 0.0136 mg/l to 1.12 mg/l and from 0.0044 mg/l to 0.43 mg/l, respectively. Only in the single case of natural mineral water the concentration of barium (1.12 mg/l), exceeded above-mentioned MAC for this metal, which is obligatory in Poland and the European Union - 1.0 mg/l. The long-term monitoring of barium concentration in another natural mineral water (2006 - 2010), in which incidental exceeding MAC was observed in 2006, was conducted. All measured barium concentrations in this water were lower than 1.0 mg/l and therefore, it is possible to state that the proper method of mixing waters taken from six independent

  1. Ammonia and ammonium over the southern Baltic Sea. Part 1. Preparation of aerosol and air samples for the determination of ammonia by the indophenol method

    Directory of Open Access Journals (Sweden)

    Lucyna Falkowska

    2004-06-01

    Full Text Available 1997 saw the start of a study into the spatial and temporal changes in the chemical composition of the atmosphere over the littoral and offshore waters of the Baltic Sea. Collection of samples and their subsequent chemical analysis was preceded by meticulous laboratory experiments concerning the validation and adaptation of the analytical procedures. The colorimetric indophenol blue technique was used to analyse the aerosol samples for the concentration of ammonium ions and the air samples for their gaseous ammonia. The samples were collected with PTFE-filters and Whatman 41 filters coated with 5% orthophosphoric acid. This acid enhances the aerosol sampling efficacy but reduces the pH of the reaction in which indophenol is formed. The pH of the aerosol samples thus had to be raised, and this in turn required an alteration to the original procedure prior to ammonia determination. It was demonstrated that the addition of 0.1 N KOH to the filters coated with H3PO4 increases the pH of the reaction medium to the required level of pH = 8-11.5 and does not substantially influence the precision of the determination; the error of the modified procedure was of the order of 5.2%.      Air samples for the determination of gaseous ammonia were collected with annular denuders. Oxalic acid and citric acid are the usual impregnating agents. In the present experiments oxalic acid was used for denuder impregnation; it turned out to be more effective than citric acid under the conditions of the southern Baltic Sea.      The detection limit of the indophenol blue method in these laboratory experiments was 0.045 mmol dm-3. The respective relative standard deviations (RSD within the range of higher and lower concentrations were 0.64% and 4.53%.

  2. Molecular determinants for drug-receptor interactions. Part 2. An ab initio molecular orbital and dipole moment study of the novel nootropic agent piracetam (2-oxopyrrolidin-1-ylacetamide)

    Science.gov (United States)

    Lumbroso, H.; Liégeois, C.; Pappalardo, G. C.; Grassi, A.

    From the ab initio molecular energies of the possible conformers and from a classical dipole moment analysis of 2-oxopyrrolidin-l-ylacetamide (μ = 4.02 D in dioxan at 30.0°C), the preferred conformation in solution of this novel nootropic agent has been determined. The exocyclic N-CH 2 bond is rotated in one sense by 90° and the exocyclic CH 2-C bond rotated in the same sense by 120° from the "planar" ( OO)- cis conformation. The structures of the two enantiomers in solution differ from that of the crystalline molecule.

  3. Laser-induced fluorescence with an OPO system. Part II: direct determination of lead content in seawater by electrothermal atomization-laser-excited atomic fluorescence (ETA-LEAF).

    Science.gov (United States)

    Le Bihan, A; Lijour, Y; Giamarchi, P; Burel-Deschamps, L; Stephan, L

    2003-03-01

    Fluorescence was induced by coupling a laser with an optical parametric oscillator (OPO) to develop an analytical method for the direct determination of lead content, at ultra-trace level, in seawater by electrothermal atomization-laser-excited atomic fluorescence (ETA-LEAF). The optimization of atomization conditions, laser pulse energy, and mainly temporal parameters allowed us to reach a 3 fg detection limit (0.3 ng L(-1)) despite the low repetition rate of the device. The expected error on predicted concentrations of lead, at trace levels, in seawater was below 15%.

  4. [Determination of barium in natural curative waters by ICP-OES technique. Part I. Waters taken on the area of health resorts in Poland].

    Science.gov (United States)

    Garboś, Sławomir; Swiecicka, Dorota

    2011-01-01

    Maximum admissible concentration level (MACL) of barium in natural mineral waters, natural spring waters and potable waters was set at the level of 1 mg/l, while MACL of this element in natural curative waters intended for drinking therapies and inhalations were set at the levels of 1.0 mg/l and 10.0 mg/l, respectively. Those requirements were related to therapies which are applied longer than one month. Above mentioned maximum admissible concentration levels of barium in consumed waters were established after taking into account actual criteria of World Health Organization which determined the guidelines value for this element in water intended for human consumption at the level of 0.7 mg/l. In this work developed and validated method of determination of barium by inductively coupled plasma emission spectrometry technique was applied for determination of this element in 45 natural curative waters sampled from 24 spa districts situated on the area of Poland. Concentrations of barium determined were in the range from 0.0036 mg/l to 24.0 mg/l. Natural curative waters characterized by concentrations of barium in the ranges of 0.0036 - 0.073 mg/l, 0.0036 - 1.31 mg/l and 0.0036 - 24.0 mg/l, were applied to drinking therapy, inhalations and balneotherapy, respectively (some of waters analyzed were simultaneously applied to drinking therapy, inhalations and balneotherapy). In the cases of 11 natural curative waters exceeding limit of 1 mg/l were observed, however they were classified mainly as waters applied to balneotherapy and in two cases to inhalation therapies (concentrations of barium - 1.08 mg/l and 1.31 mg/l). The procedure of classification of curative waters for adequate therapies based among other things on barium concentrations meets requirements of the Decree of Minister of Health from 13 April 2006 on the range of studies indispensable for establishing medicinal properties of natural curative materials and curative properties of climate, criteria of their

  5. Water isotope composition as a tracer for study of mixing processes in rivers. Part II. Determination of mixing degrees in the tributary-main river systems

    International Nuclear Information System (INIS)

    Owczarczyk, A.; Wierzchnicki, R.; Zimnicki, R.; Ptaszek, S.; Palige, J.; Dobrowolski, A.

    2006-01-01

    Two river-tributary systems have been chosen for the investigation of mixing processes: the Narew River-the Bug River-Zegrzynski Reservoir and the Bugo-Narew River-the Vistula River. In both river systems, several profiles for the water sampling have been selected down to the tributary confluent line. Each sample position has been precisely determined by means of GPS. Then, the δDi have been measured in IRMS (isotope ratio mass spectroscopy). The δD distributions in selected profiles have been presented for both investigated river systems. Presented results will be applied for the verification of the mathematical model for transport and mixing in river systems

  6. Compartmentalized beta subunit distribution determines characteristics and ethanol sensitivity of somatic, dendritic, and terminal large-conductance calcium-activated potassium channels in the rat central nervous system.

    Science.gov (United States)

    Wynne, P M; Puig, S I; Martin, G E; Treistman, S N

    2009-06-01

    Neurons are highly differentiated and polarized cells, whose various functions depend upon the compartmentalization of ion channels. The rat hypothalamic-neurohypophysial system (HNS), in which cell bodies and dendrites reside in the hypothalamus, physically separated from their nerve terminals in the neurohypophysis, provides a particularly powerful preparation in which to study the distribution and regional properties of ion channel proteins. Using electrophysiological and immunohistochemical techniques, we characterized the large-conductance calcium-activated potassium (BK) channel in each of the three primary compartments (soma, dendrite, and terminal) of HNS neurons. We found that dendritic BK channels, in common with somatic channels but in contrast to nerve terminal channels, are insensitive to iberiotoxin. Furthermore, analysis of dendritic BK channel gating kinetics indicates that they, like somatic channels, have fast activation kinetics, in contrast to the slow gating of terminal channels. Dendritic and somatic channels are also more sensitive to calcium and have a greater conductance than terminal channels. Finally, although terminal BK channels are highly potentiated by ethanol, somatic and dendritic channels are insensitive to the drug. The biophysical and pharmacological properties of somatic and dendritic versus nerve terminal channels are consistent with the characteristics of exogenously expressed alphabeta1 versus alphabeta4 channels, respectively. Therefore, one possible explanation for our findings is a selective distribution of auxiliary beta1 subunits to the somatic and dendritic compartments and beta4 to the terminal compartment. This hypothesis is supported immunohistochemically by the appearance of distinct punctate beta1 or beta4 channel clusters in the membrane of somatic and dendritic or nerve terminal compartments, respectively.

  7. Time-scale and extent at which large-scale circulation modes determine the wind and solar potential in the Iberian Peninsula

    International Nuclear Information System (INIS)

    Jerez, Sonia; Trigo, Ricardo M

    2013-01-01

    The North Atlantic Oscillation (NAO), the East Atlantic (EA) and the Scandinavian (SCAND) modes are the three main large-scale circulation patterns driving the climate variability of the Iberian Peninsula. This study assesses their influence in terms of solar (photovoltaic) and wind power generation potential (SP and WP) and evaluates their skill as predictors. For that we use a hindcast regional climate simulation to retrieve the primary meteorological variables involved, surface solar radiation and wind speed. First we identify that the maximum influence of the various modes occurs on the interannual variations of the monthly mean SP and WP series, being generally more relevant in winter. Second we find that in this time-scale and season, SP (WP) varies up to 30% (40%) with respect to the mean climatology between years with opposite phases of the modes, although the strength and the spatial distribution of the signals differ from one month to another. Last, the skill of a multi-linear regression model (MLRM), built using the NAO, EA and SCAND indices, to reconstruct the original wintertime monthly series of SP and WP was investigated. The reconstructed series (when the MLRM is calibrated for each month individually) correlate with the original ones up to 0.8 at the interannual time-scale. Besides, when the modeled series for each individual month are merged to construct an October-to-March monthly series, and after removing the annual cycle in order to account for monthly anomalies, these correlate 0.65 (0.55) with the original SP (WP) series in average. These values remain fairly stable when the calibration and reconstruction periods differ, thus supporting up to a point the predictive potential of the method at the time-scale assessed here. (letter)

  8. The determination of acrylamide in environmental and drinking waters by large-volume injection - hydrophilic-interaction liquid chromatography and tandem mass spectrometry.

    Science.gov (United States)

    Backe, Will J; Yingling, Virginia; Johnson, Todd

    2014-03-21

    A simple and sensitive analytical method was developed to quantify levels of acrylamide in environmental and drinking waters. The analytical method consisted of solvent exchanging acrylamide from 2mL of water into 2mL of dichloromethane using acetonitrile as an intermediate. The sample was then directly analyzed by large-volume (750μL) injection - hydrophilic-interaction liquid chromatography and tandem mass spectrometry. The method detection limit and reporting level were 2.4ng/L and 17ng/L of acrylamide, respectively. The recovery of acrylamide during solvent exchange was 95±2.8% and the matrix effects were 12±2.2% in river water. The use of atmospheric-pressure chemical ionization reduced matrix effects; however, it also reduced method sensitivity by a factor of 2.2 compared to electrospray ionization. Matrix effects were compensated for by the use of an isotopically-labeled internal standard and the method accuracy was 89±3.0% at 25ng/L of acrylamide and 102±2.6% at 250ng/L of acrylamide. The precision of the method was less than 6% relative standard deviation at both 25ng/L and 250ng/L of acrylamide. Samples from a sand-and-gravel mine and a drinking-water treatment plant were acquired to demonstrate the method. The concentrations of acrylamide at the sand-and-gravel mine were up to 280ng/L. In the drinking-water treatment plant, the concentration of acrylamide was approximately double in the finished drinking water when compared to other stages in the drinking-water treatment process. Disinfection or fluoridation may result in higher concentrations of acrylamide in finished drinking water; however, further research in this area is necessary. Copyright © 2014 Elsevier B.V. All rights reserved.

  9. Determination of the Clean Air Delivery Rate (CADR of Photocatalytic Oxidation (PCO Purifiers for Indoor Air Pollutants Using a Closed-Loop Reactor. Part I: Theoretical Considerations

    Directory of Open Access Journals (Sweden)

    Éric Dumont

    2017-03-01

    Full Text Available This study demonstrated that a laboratory-scale recirculation closed-loop reactor can be an efficient technique for the determination of the Clean Air Delivery Rate (CADR of PhotoCatalytic Oxidation (PCO air purification devices. The recirculation closed-loop reactor was modeled by associating equations related to two ideal reactors: one is a perfectly mixed reservoir and the other is a plug flow system corresponding to the PCO device itself. Based on the assumption that the ratio between the residence time in the PCO device and the residence time in the reservoir τP/τR tends to 0, the model highlights that a lab closed-loop reactor can be a suitable technique for the determination of the efficiency of PCO devices. Moreover, if the single-pass removal efficiency is lower than 5% of the treated flow rate, the decrease in the pollutant concentration over time can be characterized by a first-order decay model in which the time constant is proportional to the CADR. The limits of the model are examined and reported in terms of operating conditions (experiment duration, ratio of residence times, and flow rate ranges.

  10. Winter ecology of the Porcupine caribou herd, Yukon: Part III, Role of day length in determining activity pattern and estimating percent lying

    Directory of Open Access Journals (Sweden)

    D. E. Russell

    1986-06-01

    Full Text Available Data on the activity pattern, proportion of time spent lying and the length of active and lying periods in winter are presented from a 3 year study on the Porcupine caribou herd. Animals were most active at sunrise and sunset resulting in from one (late fall, early and mid winter to two (early fall and late winter to three (spring intervening lying periods. Mean active/lying cycle length decreased from late fall (298 mm to early winter (238 min, increased to a peak in mid winter (340 min then declined in late winter (305 min and again in spring (240 min. Mean length of the lying period increased throughout the 3 winter months from 56 min m early winter to 114 min in mid winter and 153 min in late winter. The percent of the day animals spent lying decreased from fall to early winter, increased throughout the winter and declined in spring. This pattern was related, in part, to day length and was used to compare percent lying among herds. The relationship is suggested to be a means of comparing quality of winter ranges.

  11. A comparison of social and spatial determinants of health between formal and informal settlements in a large metropolitan setting in Brazil.

    Science.gov (United States)

    Snyder, Robert E; Jaimes, Guillermo; Riley, Lee W; Faerstein, Eduardo; Corburn, Jason

    2014-06-01

    Urban informal settlements are often under-recognized in national and regional surveys. A lack of quality intra-urban data frequently contributes to a one-size-fits-all public health intervention and clinical strategies that rarely address the variegated socioeconomic disparities across and within different informal settlements in a city. The 2010 Brazilian census gathered detailed population and place-based data across the country's informal settlements. Here, we examined key socio-demographic and infrastructure characteristics that are associated with health outcomes in Rio de Janeiro with the census tract as the unit of analysis. Many of the city's residents (1.39 million people, 22 % of the population) live in informal settlements. Residents of census tracts in Rio de Janeiro's urban informal areas are younger, (median age of 26 versus 35 years in formal settlements), and have less access to adequate water (96 versus 99 % of informal households), sanitation (86 versus 96 %), and electricity (67 versus 92 %). Average per household income in informal settlement census tracts is less than one third that of non-informal tracts (US\\$708 versus US\\$2362). Even among informal settlements in different planning areas in the same city, there is marked variation in these characteristics. Public health interventions, clinical management, and urban planning policies aiming to improve the living conditions of the people residing in informal settlements, including government strategies currently underway, must consider the differences that exist between and within informal settlements that shape place-based physical and social determinants of health.

  12. Cavitation and non-cavitation regime for large-scale ultrasonic standing wave particle separation systems--In situ gentle cavitation threshold determination and free radical related oxidation.

    Science.gov (United States)

    Johansson, Linda; Singh, Tanoj; Leong, Thomas; Mawson, Raymond; McArthur, Sally; Manasseh, Richard; Juliano, Pablo

    2016-01-01

    We here suggest a novel and straightforward approach for liter-scale ultrasound particle manipulation standing wave systems to guide system design in terms of frequency and acoustic power for operating in either cavitation or non-cavitation regimes for ultrasound standing wave systems, using the sonochemiluminescent chemical luminol. We show that this method offers a simple way of in situ determination of the cavitation threshold for selected separation vessel geometry. Since the pressure field is system specific the cavitation threshold is system specific (for the threshold parameter range). In this study we discuss cavitation effects and also measure one implication of cavitation for the application of milk fat separation, the degree of milk fat lipid oxidation by headspace volatile measurements. For the evaluated vessel, 2 MHz as opposed to 1 MHz operation enabled operation in non-cavitation or low cavitation conditions as measured by the luminol intensity threshold method. In all cases the lipid oxidation derived volatiles were below the human sensory detection level. Ultrasound treatment did not significantly influence the oxidative changes in milk for either 1 MHz (dose of 46 kJ/L and 464 kJ/L) or 2 MHz (dose of 37 kJ/L and 373 kJ/L) operation. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. Measurement of large asymptotic reactor periods from about 103 to 4.104 sec) to determine reactivity effects of small samples

    International Nuclear Information System (INIS)

    Grinevich, F.A.; Evchuk, A.I.; Klimentov, V.B.; Tyzh, A.V.; Churkin, Yu.I.; Yaroshevich, O.I.

    1977-01-01

    All investigation programs on fast reactor physics include measurements of low reactivity values (1-0.01)x10 -5 ΔK/K. An application of the pile oscillator technique for the purpose requires a special critical assembly for an installation of the oscillator. Thus it is of interest to develop relatively simple methods. In particular, one of such methods is the asymptotic period method which is widely used for low reactivity measurements. The description of the method and equipment developed for low reactivity measurements according to the measurements of the steady-state reactor period is presented. The equipment has been tested on the BTS-2 fast-thermal critical assembly. Measurement results on the reactivity effects of small samples in the fast zone centre are given. It is shown that the application of the method of measuring long steady-state periods and developed and tested equipment enables the reactivity of (1+-0.02)x10 -5 ΔK/K to be determined at the critical assembly power of 5 to 10 Wt. The disadvantage of the method presented is the time lost on reaching the steady-state period which results in greater sensitivity of the method to reactivity drifts

  14. Potential spread of highly pathogenic avian influenza H5N1 by wildfowl: dispersal ranges and rates determined from large-scale satellite telemetry

    Science.gov (United States)

    Gaidet, Nicolas; Cappelle, Julien; Takekawa, John Y.; Prosser, Diann J.; Iverson, Samuel A.; Douglas, David C.; Perry, William M.; Mundkur, Taej; Newman, Scott H.

    2010-01-01

    1. Migratory birds are major candidates for long-distance dispersal of zoonotic pathogens. In recent years, wildfowl have been suspected of contributing to the rapid geographic spread of the highly pathogenic avian influenza (HPAI) H5N1 virus. Experimental infection studies reveal that some wild ducks, geese and swans shed this virus asymptomatically and hence have the potential to spread it as they move. 2. We evaluate the dispersive potential of HPAI H5N1 viruses by wildfowl through an analysis of the movement range and movement rate of birds monitored by satellite telemetry in relation to the apparent asymptomatic infection duration (AID) measured in experimental studies. We analysed the first large-scale data set of wildfowl movements, including 228 birds from 19 species monitored by satellite telemetry in 2006–2009, over HPAI H5N1 affected regions of Asia, Europe and Africa. 3. Our results indicate that individual migratory wildfowl have the potential to disperse HPAI H5N1 over extensive distances, being able to perform movements of up to 2900 km within timeframes compatible with the duration of asymptomatic infection. 4. However, the likelihood of such virus dispersal over long distances by individual wildfowl is low: we estimate that for an individual migratory bird there are, on average, only 5–15 days per year when infection could result in the dispersal of HPAI H5N1 virus over 500 km. 5. Staging at stopover sites during migration is typically longer than the period of infection and viral shedding, preventing birds from dispersing a virus over several consecutive but interrupted long-distance movements. Intercontinental virus dispersion would therefore probably require relay transmission between a series of successively infected migratory birds. 6. Synthesis and applications. Our results provide a detailed quantitative assessment of the dispersive potential of HPAI H5N1 virus by selected migratory birds. Such dispersive potential rests on the

  15. Determination of copper in liquid and solid insulation for large electrical equipment by ICP-OES. Application to copper contamination assessment in power transformers.

    Science.gov (United States)

    Bruzzoniti, Maria Concetta; De Carlo, Rosa Maria; Sarzanini, Corrado; Maina, Riccardo; Tumiatti, Vander

    2012-09-15

    Copper is one of the main constituents of the components in power transformers and its presence both in liquid (mineral oil) and in solid (Kraft paper) insulators can lead to enhanced dielectric losses and to the subsequent deterioration of their insulating properties. Recently the latter have been correlated to plant failures which in turn may have severe impact on the environment. This paper describes the direct analysis of copper in insulating mineral oil by ICP-OES and how it was first optimized compared to the official American Society for Testing and Materials (ASTM) D7151 method. Detection and quantification limits of 8.8 μg kg(-1) and 29.3 μg kg(-1) were obtained. Secondly, copper determination was improved by coupling a microwave assisted dissolution procedure of the mineral oil which avoided the problems, in the real samples, due to the presence of solid species of copper which cannot be nebulized following traditional methods described in literature. Sixteen mineral insulating oils sampled from transformers in service were analyzed before and after dissolution. In order to evaluate copper speciation, size fractionation was performed by filtration on PTFE filters (0.45, 1 and 5 μm). This test was performed on all the oil samples. Finally, because of the key role of the solid insulator in failed transformers, the Authors applied the developed method to study the copper deposition tendency onto the insulating Kraft paper tapes exerted by two unused oils (a corrosive and a non-corrosive one) under defined ageing conditions. Copyright © 2012 Elsevier B.V. All rights reserved.

  16. Determinants of Buying Behavior of Grain Producers: A Multiple Case Study with Mid and Large Size Producers in the State of Mato Grosso

    Directory of Open Access Journals (Sweden)

    Roberto Fava Scare

    2013-12-01

    Full Text Available In recent years, Brazilian agribusiness has demanded for inputs, capital goods, financial services and technology. In addition, there have been changes in the size of the properties, as well as in risk management and commercialization practices, and level of education and posture of those responsible for the decision making of agricultural enterprises. It is fundamental for companies that supply inputs and services to farmers to understand some variables in such changing environment, considering that they influence the business model and the buying behavior of rural producers. The purpose of this study is to develop knowledge and familiarity with the buying behavior of grain farmers in the State of Mato Grosso, with the intent of understanding how this behavior can be influenced by theproducer's profile and the farm features, as well as the risk and business management practices, the decision making, the sources of information, and the products and suppliers. In order to achieve such a goal,a multiple case study was developed by interviewing, face to face, three grain producers, from the State of Mato Grosso. The results demonstrate that the most influential determinants on the buying behavior of the interviewed producers were their level of involvement in the decision making process, the benefit they expect from each type of product, the size of their farming operation, the kind of yield production, and the crop rotation and its relation to productivity. Additionally, the ownership or not of the land, the business profitability, credit restrictions and risk management, they all influence the level of the producer's capitalization and consequently his choices of channels for acquiring inputs and capital goods. Last, though not less important, the sources of information and their reliability have an impact on the producer's loyalty to a brand, or to a local distributor or to a salesperson.

  17. Setting the pace: host rhythmic behaviour and gene expression patterns in the facultatively symbiotic cnidarian Aiptasia are determined largely by Symbiodinium.

    Science.gov (United States)

    Sorek, Michal; Schnytzer, Yisrael; Ben-Asher, Hiba Waldman; Caspi, Vered Chalifa; Chen, Chii-Shiarng; Miller, David J; Levy, Oren

    2018-05-09

    All organisms employ biological clocks to anticipate physical changes in the environment; however, the integration of biological clocks in symbiotic systems has received limited attention. In corals, the interpretation of rhythmic behaviours is complicated by the daily oscillations in tissue oxygen tension resulting from the photosynthetic and respiratory activities of the associated algal endosymbiont Symbiodinium. In order to better understand the integration of biological clocks in cnidarian hosts of Symbiodinium, daily rhythms of behaviour and gene expression were studied in symbiotic and aposymbiotic morphs of the sea-anemone Aiptasia diaphana. The results showed that whereas circatidal (approx. 12-h) cycles of activity and gene expression predominated in aposymbiotic morphs, circadian (approx. 24-h) patterns were the more common in symbiotic morphs, where the expression of a significant number of genes shifted from a 12- to 24-h rhythm. The behavioural experiments on symbiotic A. diaphana displayed diel (24-h) rhythmicity in body and tentacle contraction under the light/dark cycles, whereas aposymbiotic morphs showed approximately 12-h (circatidal) rhythmicity. Reinfection experiments represent an important step in understanding the hierarchy of endogenous clocks in symbiotic associations, where the aposymbiotic Aiptasia morphs returned to a 24-h behavioural rhythm after repopulation with algae. Whilst some modification of host metabolism is to be expected, the extent to which the presence of the algae modified host endogenous behavioural and transcriptional rhythms implies that it is the symbionts that influence the pace. Our results clearly demonstrate the importance of the endosymbiotic algae in determining the timing and the duration of the extension and contraction of the body and tentacles and temporal gene expression.

  18. Selective reduction of arsenic species by hydride generation - atomic absorption spectrometry. Part 2 - sample storage and arsenic determination in natural waters

    Directory of Open Access Journals (Sweden)

    Quináia Sueli P.

    2001-01-01

    Full Text Available Total arsenic, arsenite, arsinate and dimethylarsinic acid (DMA were selectively determined in natural waters by hydride generation - atomic absorption spectrometry, using sodium tetrahydroborate(III as reductant but in different reduction media. River water samples from the north region of Paraná State, Brazil, were analysed and showed arsenate as the principal arsenical form. Detection limits found for As(III (citrate buffer, As(III + DMA (acetic acid and As(III + As(V (hydrochloric acid were 0.6, 1.1 and 0.5 mg As L-1, respectively. Sample storage on the proper reaction media revealed to be a useful way to preserve the water sample.

  19. The determination of pesticide residues and contaminants in vegetables by means of neutron activation analysis. Part of a coordinated programme on nuclear detection and analysis

    International Nuclear Information System (INIS)

    Mongkolphanta, S.

    1977-11-01

    Neutron activation techniques have been applied to study the existence of pesticide residues (As, Br, Hg) and pollutants (Cd, Co, Zn) in local vegetable and fruit samples, polished and unpolished glutinous and non-glutinous milled rice, and fish caught in polluted and unpolluted areas of the Gulf of Thailand. Since the baseline levels of these toxic elements in vegetables, fruits, rice and fish are not known as yet, the results cannot be regarded as conclusive. Furthermore, no significant difference was observed in the concentration of these elements in fish caught in polluted and unpolluted areas. The Gulf of Thailand does not therefore appear to be polluted at present. The substoichiometric isotope dilution technique was successfully applied to mercury determinations, and only to a limited extent to Cd due to shutdown of the TRR-1 reactor

  20. Molecular allergy diagnostics using IgE singleplex determinations: methodological and practical considerations for use in clinical routine: Part 18 of the Series Molecular Allergology.

    Science.gov (United States)

    Kleine-Tebbe, Jörg; Jakob, Thilo

    Allergen molecules (synonyms: single allergens, allergen components) open up new horizons for the targeted allergen-specific diagnostics of immunoglobulin E (IgE) in singleplex determination. The following rationales support the targeted use of allergen molecules and, more importantly, improve test properties: (1) increased test sensitivity ("analytical sensitivity"), particularly when important allergens are under-represented or lacking in the extract; (2) improved test selectivity (analytical specificity), particularly when the selected IgE repertoire against an allergen yields additional information on: (a) potential risk, (b) possible cross-reactivity, or (c) primary (species-specific) sensitization. However, the appropriate indication for the use of single allergens can only be established on a case-by-case basis (depending on the clinical context and previous history) and in an allergen-specific manner (depending on the allergen source and the single allergens available), rather than in a standardized way. Numerous investigations on suspected food allergy, insect venom allergy, or sensitization to respiratory allergens have meanwhile demonstrated the successful use of defined molecules for allergen-specific singleplex IgE diagnosis. Specific IgE to single allergens is limited in its suitability to predict the clinical relevance of sensitivity on an individual basis. In food allergies, one can at best identify the relative risk of a clinical reaction on the basis of an IgE profile, but no absolutely reliable prediction on (future) tolerance can be made. Ultimately, the clinical relevance of all IgE findings depends on the presence of corresponding symptoms and can only be assessed on an individual basis (previous history, symptom log, and provocation testing with the relevant allergen source where appropriate). Thus, also in molecular allergology, the treating physician and not the test result should determine the clinical relevance of diagnostic findings

  1. Determination of the detection limit and decision threshold for ionizing radiation measurements. Part 3: Fundamentals and application to counting measurements by high resolution gamma spectrometry, without the influence of sample treatment

    International Nuclear Information System (INIS)

    2000-01-01

    This part of ISO 11929 addresses the field of ionizing radiation measurements in which events (in particular pulses) are counted by high resolution gamma spectrometry registrating a pulse-heights distribution (acquisition of a multichannel spectrum), for example on samples. It considers exclusively the random character of radioactive decay and of pulse counting and ignores all other influences (e.g. arising from sample treatment, weighing, enrichment or the instability of the test setup). It assumes that the distance of neighbouring peaks of gamma lines is not smaller than four times the full width half maximum (FWHM) of gamma line and that the background near to gamma line is nearly a straight line. Otherwise ISO 11929-1 or ISO 11929-2 should be used. ISO 11929 consists of the following parts, under the general title Determination of the detection limit and decision threshold for ionizing radiation measurements: Part 1: Fundamentals and application to counting measurements without the influence of sample treatment; Part 2: Fundamentals and application to counting measurements with the influence of sample treatment; Part 3: Fundamentals and application to counting measurements by high resolution gamma spectrometry, without the influence of sample treatment; Part 4: Fundamentals and application to measurements by use of linear scale analogue ratemeters, without the influence of sample treatment. This part of ISO 11929 was prepared in parallel with other International Standards prepared by WG2 (now WG 17): ISO 11932:1996, Activity measurements of solid materials considered for recycling, re-use or disposal as nonradioactive waste, and ISO 11929-1, ISO 11929-2 and ISO 11929-4, and is, consequently, complementary to these documents

  2. Tsuwalhkalh Ti Tmicwa (The Land is Ours): Stat'imc Self-Determination in the Face of Large-Scale Hydro-electric Development

    Science.gov (United States)

    Moritz, Sarah Carmen

    In Canada, First Nations asserting authority over their lands are developing diverse strategies to overcome the state''s dogmatic insistence on jurisdictional sovereignty. This movement corresponds to the wider context of the challenges faced by indigenous people to use their own ways of knowing to resist or reformulate legal doctrines and political tenets based on colonial power. Interior Salish Stat'imc people identify themselves through a strong and ongoing social relationship with Sataqwa7, the Fraser River, and the "Valley of Plenty"---now known as the flooded Bridge River Valley---maintained through Stat'imc knowledge and cultural practice and demonstrated by talk of '"the Stat'imc right to fish" and Tsuwalhkalh Ti Tmicwa (The Land is Ours). Stat'imc fishers are prepared to contest and resist any regulatory system that is understood to impact this right to fish while they advocate their own ways of sustainable fishing and water management. Based on ethnographic research in collaboration with Stat'imc people, this thesis explores some of these often successful contestations especially in the context of increasing territorial governance and by example of the rapidly transforming relationship between Stat'imc, BC Hydro and the Province of BC. Interior Salish Stat'imc people are currently navigating through a significant phase of increasing jurisdiction and authority and recognition of (unsettled) territorial property relationships. This very dynamic process is marked by strategic collaborations, compensation for 'infringements' on St'a'imc Title and Rights, and conservation efforts to protect their home. An important example is the changing relationship between Stat'imc people and BC Hydro---a relationship between two groups with radically different cultures and agendas: Stat'imc people in a struggle for self-determination, social justice and cultural survival and BC Hydro, a corporate culture, with the agenda to provide hydro-electric power to BC, maintain

  3. Atacama Desert: Determination of two new extremophilic microbial model systems for space exploration and astrobiology studies - data from a large-scale transect study

    Science.gov (United States)

    Boy, Diana; Godoy, Roberto; Guggenberger, Georg; Möller, Ralf; Boy, Jens

    2017-04-01

    The hyper-arid region of Yungay in the Atacama Desert in Chile is believed to be the driest place on Earth thus harboring the most desiccation-resistant microorganisms. Hence the search for new extremophilic model organisms is traditionally limited to this rather narrow strip. However, it is not clear whether Yungay is indeed the most arid place, as this should be the one with the lowest soil organic carbon (SOC) stock and soil water (SW) content. Therefore we tested soil samples from a humidity-gradient transect with comparable sites (inclination, location in the rain shadow of the coastal mountain range, 100 km distance between the sites) spanning roughly 600 km in the Atacama Desert for SOC stocks and SW content. We found, that SOC stocks decreased with aridity from 25.5 to 2.1 kg m-2 cm-1, while the SW contents decreased at 5 of our sites and increased in the hyper-arid zone. To our surprise, we identified two sites located 100 km north and south of Yungay which had substantially lower (1.92 ± 0.73 kg m-2 cm-1) or slightly higher (2.39 ± 1.2 kg m-2 cm-1) SOC stocks than Yungay (2.21 ± 0.75 kg m-2 cm-1), but with 0.043 ± 0.03 g respectively 0.0033 ± 0.0016 g of water per 1 g of soil comparable or substantially lower SW contents, while Yungay has 0.043 ± 0.06 g. Thus we consider these sites to display different growth conditions and ecological niches compared to Yungay and therefore as promising candidate sites for the identification of new species of polyextremophilic radiation-resistant microorganisms, as the resistance against desiccation is paired with a distinct resistance to ionizing radiation due to same microbial DNA repair mechanisms. Soil samples were irradiated with high doses of gamma radiation up to 25 000 Gy. Surviving colonies were cultivated on a medium favoring the growth of Deinococcus-like species, currently the most radiation-resistant organisms on Earth, and their affiliation was determined using 16SrRNA next generation sequencing. Here

  4. Study of High-Resolution Spectroscopy of Plutonium. Part I. Contribution to the Classification of the Arc Spectrum. Part II. Determination of the Magnetic Moment of {sup 239}Pu; Etude du plutonium par spectroscopie a haute resolution: contribution a la classification du spectre d'arc et determination du moment magnetique de {sup 239}Pu

    Energy Technology Data Exchange (ETDEWEB)

    Gerstenkorn, S

    1962-07-01

    The study of the hyperfine structure and isotope shift enabled the positions of the first five levels of the multiplet {sup 7}F{sub 0-6} belonging to the fundamental configuration 5f{sup 6}7s{sup 2} to be determined. The classification of the arc spectrum begun in this way led to 25 odd levels, the number of classified lines (70) representing about 30 p. 100 of the light emitted by this hollow cathode in the visible. In addition, the isotope shifts of many lines and the data given by the King furnace show that the first levels of the configuration 5f{sup 5}6d7s{sup 2} are also low less than 8000 cm{sup -1} above the fundamental level {sup 7}F{sub 0}. The proximity of the configuration f{sup 6}s{sup 2} and f{sup 5}ds{sup 2} shows that the bonding energies of the 5f and 6d electrons are of the same order of magnitude and this fact must be responsible for the multiple valences belonging to plutonium. From the hyperfine structure of spark lines (Pu II) the interval factor a{sub 7} for the electron was deduced giving for the calculated nuclear moment of {sup 239}Pu a value of +0.21 {+-}0.06 {mu}{sub N}. The position of the hyperfine components show that the nuclear moment is positive, although the theoretical value given by B. R. Mottelson and S. Nillson is negative and equal to -0.1 {mu}{sub N}. (author) [French] Partie 1 - L'etude des structures hyperfines et du deplacement isotopique des raies du spectre d'arc du plutonium a permis de determiner la position des cinq premiers niveaux du multiplet {sup 7}F{sub 0-6} correspondant a la configuration fondamentale 5f{sup 6}7s{sup 2}. Des lors, la classification du spectre d'arc du plutonium pouvait etre amorcee: 25 niveaux impairs ont ete mis en evidence et le nombre de raies classees (70) represente environ 30 p. 100 de l'intensite totale du spectre d'arc emis par une cathode creuse dans le visible. D'autre part, le deplacement isotopique de certaines raies, joint aux renseignements donnes par le spectre emis par le four

  5. Pesticide exposure assessment for surface waters in the EU. Part 2: Determination of statistically based run-off and drainage scenarios for Germany.

    Science.gov (United States)

    Bach, Martin; Diesner, Mirjam; Großmann, Dietlinde; Guerniche, Djamal; Hommen, Udo; Klein, Michael; Kubiak, Roland; Müller, Alexandra; Preuss, Thomas G; Priegnitz, Jan; Reichenberger, Stefan; Thomas, Kai; Trapp, Matthias

    2017-05-01

    In order to assess surface water exposure to active substances of plant protection products (PPPs) in the European Union (EU), the FOCUS (FOrum for the Co-ordination of pesticide fate models and their USe) surface water workgroup introduced four run-off and six drainage scenarios for Step 3 of the tiered FOCUSsw approach. These scenarios may not necessarily represent realistic worst-case situations for the different Member States of the EU. Hence, the suitability of the scenarios for risk assessment in the national authorisation procedures is not known. Using Germany as an example, the paper illustrates how national soil-climate scenarios can be developed to model entries of active substances into surface waters from run-off and erosion (using the model PRZM) and from drainage (using the model MACRO). In the authorisation procedure for PPPs on Member State level, such soil-climate scenarios can be used to determine exposure endpoints with a defined overall percentile. The approach allows the development of national specific soil-climate scenarios and to calculate percentile-based exposure endpoints. The scenarios have been integrated into a software tool analogous to FOCUS-SWASH which can be used in the future to assess surface water exposure in authorisation procedures of PPPs in Germany. © 2017 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry. © 2017 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

  6. Modeling of adsorption isotherms of phenol and chlorophenols onto granular activated carbon. Part I. Two-parameter models and equations allowing determination of thermodynamic parameters.

    Science.gov (United States)

    Hamdaoui, Oualid; Naffrechoux, Emmanuel

    2007-08-17

    The adsorption equilibrium isotherms of five phenolic compounds from aqueous solutions onto granular activated carbon (GAC) were studied and modeled. Phenol (Ph), 2-chlorophenol (2-CP), 4-chlorophenol (4-CP), 2,4-dichlorophenol (DCP), and 2,4,6-trichlorophenol (TCP) were chosen for the adsorption tests. To predict the adsorption isotherms and to determine the characteristic parameters for process design, seven isotherm models: Langmuir (five linear forms), Freundlich, Elovich, Temkin, Fowler-Guggenheim, Kiselev, and Hill-de Boer models were applied to experimental data. The results reveal that the adsorption isotherm models fitted the data in the order: Fowler-Guggenheim>Hill-de Boer>Temkin>Freundlich>Kiselev>Langmuir isotherms. Adsorption isotherms modeling shows that the interaction of phenolic compounds with activated carbon surface is localized monolayer adsorption, that is adsorbed molecules are adsorbed at definite, localized sites. Each site can accommodate only one molecule. The interaction among adsorbed molecules is repulsive and there is no association between them, adsorption is carried out on energetically different sites and is an exothermic process. Uptake of phenols increases in the order Ph<2-CP<4-CP

  7. Comprehensive determination of flavouring additives and nicotine in e-cigarette refill solutions. Part I: Liquid chromatography-tandem mass spectrometry analysis.

    Science.gov (United States)

    Aszyk, Justyna; Kubica, Paweł; Kot-Wasik, Agata; Namieśnik, Jacek; Wasik, Andrzej

    2017-10-13

    Liquid chromatography-tandem mass spectrometry with electrospray ionization (HPLC-ESI-MS/MS) methods were developed for the simultaneous determination of 42 flavouring compounds and nicotine in liquids for e-cigarettes. The chromatographic separation was performed using an Ace ® Ultracore™ SuperC18™ (100×2.1mm, 2.5μm) column in both acidic and alkaline pH conditions to separate all the compounds. A simple "dilute & shoot" approach was used for the sample preparation. The method validation was performed by evaluating key analytical parameters such as linearity, accuracy, selectivity, precision, limit of detection (LOD) and limit of quantification (LOQ). The calibration curves showed good linearity within the specific ranges for the investigated compounds with correlation coefficients greater than 0.990 in each case. The recovery for all the investigated compounds varied from 89% to 110%. The intra- and inter-day precision were within the acceptable limits (±15%) at all tested concentrations. The applicability of the methods was examined by analysing 25 liquid samples from e-cigarettes commercially available on the Polish market. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Determination of pesticide residues in leafy vegetables at parts per billion levels by a chemometric study using GC-ECD in Cameron Highlands, Malaysia.

    Science.gov (United States)

    Farina, Yang; Abdullah, Md Pauzi; Bibi, Nusrat; Khalik, Wan Mohd Afiq Wan Mohd

    2017-06-01

    A simple and sensitive analytical method has been developed employing gas chromatography coupled with electron capture detector (GC-ECD), and validated for screening and quantification of 15 pesticide residues at trace levels in cabbage, broccoli, cauliflower, lettuce, celery, spinach, and mustard. The method consists of two steps, first, to determine the significance of each factor by Pareto chart followed by optimization of these significant factors using central composite design (CCD). Minitab statistical software was used for these multivariate experiments for the generation of 2 4-1 design and CCD matrices. The method evaluation was done by external standard calibration with linearity range between 0.5 and 3mg/kg, with correlation coefficient 0.99, limit of detection (LOD) ranges between 0.02 and 4.5ng/g, and limit of quantification (LOQ) ranges between 0.2 and 45ng/g. The average recovery was between 60% and 128%, with RSD 0.2-19.8%. The method was applied on real vegetable samples from Cameron Highlands. Copyright © 2016 Elsevier Ltd. All rights reserved.

  9. A rapid and practical strategy for the determination of platinum, palladium, ruthenium, rhodium, iridium and gold in large amounts of ultrabasic rock by inductively coupled plasma optical emission spectrometry combined with ultrasound extraction

    Science.gov (United States)

    Zhang, Gai; Tian, Min

    2015-04-01

    This proposed method regulated the determination of platinum, palladium, ruthenium, rhodium, iridium and gold in platinum-group ores by nickel sulfide fire assay—inductively coupled plasma optical emission spectrometry (ICP-OES) combined with ultrasound extraction for the first time. The quantitative limits were 0.013-0.023μg/g. The samples were fused to separate the platinum-group elements from matrix. The nickel sulfide button was then dissolved with hydrochloric acid and the insoluble platinum-group sulfide residue was dissolved with aqua regia by ultrasound bath and finally determined by ICP-OES. The proposed method has been applied into the determination of platinum-group element and gold in large amounts of ultrabasic rocks from the Great Dyke of Zimbabwe.

  10. Chemical fingerprint and simultaneous determination of alkaloids and flavonoids in aerial parts of genus Peganum indigenous to China based on HPLC-UV: application of analysis on secondary metabolites accumulation.

    Science.gov (United States)

    Wen, Fangfang; Cheng, Xuemei; Liu, Wei; Xuan, Min; Zhang, Lei; Zhao, Xin; Shan, Meng; Li, Yan; Teng, Liang; Wang, Zhengtao; Wang, Changhong

    2014-12-01

    The aerial parts of genus Peganum are officially used in traditional Chinese medicine. The paper aims to establish a high-performance liquid chromatography (HPLC) method for fingerprint analysis and simultaneous determination of three alkaloids and two flavonoids in aerial parts of genus Peganum, and to analyze accumulative difference of secondary metabolites in inter-species, individuals of plants, inter-/intra-population and from different growing seasons. HPLC analysis was performed on a C18 column with gradient elution using 0.1% trifloroacetic acid and acetonitrile as mobile phase and detected at 265 nm, by conventional methodology validation. For fingerprint analysis, the RSDs of relative retention time and relative peak area of the characteristic peaks were within 0.07-0.78 and 0.94-9.09%, respectively. For simultaneous determination of vasicine, harmaline, harmine, deacetylpeganetin and peganetin, all calibration curves showed good linearity (r > 0.9990) within the test range. The relative standard deviations of precision, repeatability and stability test did not exceed 2.37, 2.68 and 2.67%, respectively. The average recoveries for the five analytes were between 96.47 and 101.20%. HPLC fingerprints play a minor role in authenticating and differentiating the herbs of different species of genus Peganum. However, the secondary metabolites levels of alkaloids and flavonoids in aerial parts of genus Peganum rely on species-, habitat-, and growth season-dependent accumulation. Copyright © 2014 John Wiley & Sons, Ltd.

  11. Theoretic and Experimental Studies on the Casting of Large Die-Type Parts Made of Lamellar Graphite Grey Pig Irons by Using the Technology of Polystyrene Moulds Casting from Two Sprue Cups

    Directory of Open Access Journals (Sweden)

    Constantin Marta

    2012-01-01

    Full Text Available This paper presents a comparative analysis between the practical results of pig iron die-type part casting and the results reached by simulation. The insert was made of polystyrene, and the casting was downward vertical. As after the part casting and heat treatment cracks were observed in the part, it became necessary to locate and identify these fissures and to establish some measures for eliminating the casting defects and for locating them. The research method was the comparisons of defects identified through verifications, measurements, and metallographic analyses applied to the cast part with the results of some criteria specific to simulation after simulating the casting process. In order to verify the compatibility between reality and simulation, we then simulated the part casting respecting the real conditions in which it was cast. By visualising certain sections of the cast part during solidification, relevant details occur about the possible evolution of defects. The simulation software was AnyCasting, the measurements were done through nondestructive methods.

  12. Motorcycle Parts

    Science.gov (United States)

    1993-01-01

    An article in NASA Tech Briefs describing a vacuum bagging process for forming composite parts helped a small Oklahoma Company to improve its manufacturing process. President of Performance Extremes, Larry Ortega, and his partners make motorcycle parts from carbon/epoxy to reduce weight. Using vacuum bags, parts have a better surface and fewer voids inside. When heat used in the vacuum bag process caused deformation upon cooling, a solution found in another tech brief solved the problem. A metal plate inside the vacuum bag made for more even heat transfer. A third article described a simple procedure for repairing loose connector pins, which the company has also utilized.

  13. Determination of small amounts of nitric acid in the presence of large amounts of uranium (VI) and extraction of nitric acid into TBP solutions highly loaded with uranyl nitrate

    International Nuclear Information System (INIS)

    Kolarik, Z.; Schuler, R.

    1982-10-01

    A new method for the determination of small amounts of nitric acid in the presence of large amounts of uranium(VI) was elaborated. The method is based on the precipitation of uranium(VI) as iodate and subsequent alkalimetric titration of the acid in the supernatant. The extraction of nitric acid and uranium(VI) with 30% TBP in dodecane was studied at high loading of the organic phase with uranyl nitrate and at 25, 40 and 60 0 C. The results are compared with available published data on the extraction of nitric acid under similar conditions. (orig.) [de

  14. Large deviations

    CERN Document Server

    Deuschel, Jean-Dominique; Deuschel, Jean-Dominique

    2001-01-01

    This is the second printing of the book first published in 1988. The first four chapters of the volume are based on lectures given by Stroock at MIT in 1987. They form an introduction to the basic ideas of the theory of large deviations and make a suitable package on which to base a semester-length course for advanced graduate students with a strong background in analysis and some probability theory. A large selection of exercises presents important material and many applications. The last two chapters present various non-uniform results (Chapter 5) and outline the analytic approach that allow

  15. Uranium Determination in Samples from Decommissioning of Nuclear facilities Related to the First Stage of Nuclear Fuel Cycle; Determinacion de Uranio en Muestras Procedentes del Desmantelamiento de Instalaciones de la Primera Parte del Cielo del Combustible Nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Alvarez, A; Correa, E; Navarro, N; Sancho, C [Ciemat, Madrid (Spain); Angeles, A

    2000-07-01

    An adequate workplace monitoring must be carried out during the decommissioning activities, to ensure the protection of workers involved in these tasks. In addition, a large amount of waste materials are generated during the decommissioning of nuclear facilities. Clearance levels are established by regulatory authorities and are normally quite low. The determination of those activity concentration levels become more difficult when it is necessary to quantify alpha emitters such as uranium, especially when complex matrices are involved. Several methods for uranium determination in samples obtained during the decommissioning of a facility related to the first stage of the nuclear fuel cycle are presented in this work. Measurements were carried out by laboratory techniques. In situ gamma spectrometry was also used to perform measurements on site. A comparison among the different techniques was also done by analysing the results obtained in some practical applications. (Author)

  16. A large-scale electrophoresis- and chromatography-based determination of gene expression profiles in bovine brain capillary endothelial cells after the re-induction of blood-brain barrier properties

    Directory of Open Access Journals (Sweden)

    Duban-Deweer Sophie

    2010-11-01

    Full Text Available Abstract Background Brain capillary endothelial cells (BCECs form the physiological basis of the blood-brain barrier (BBB. The barrier function is (at least in part due to well-known proteins such as transporters, tight junctions and metabolic barrier proteins (e.g. monoamine oxidase, gamma glutamyltranspeptidase and P-glycoprotein. Our previous 2-dimensional gel proteome analysis had identified a large number of proteins and revealed the major role of dynamic cytoskeletal remodelling in the differentiation of bovine BCECs. The aim of the present study was to elaborate a reference proteome of Triton X-100-soluble species from bovine BCECs cultured in the well-established in vitro BBB model developed in our laboratory. Results A total of 215 protein spots (corresponding to 130 distinct proteins were identified by 2-dimensional gel electrophoresis, whereas over 350 proteins were identified by a shotgun approach. We classified around 430 distinct proteins expressed by bovine BCECs. Our large-scale gene expression analysis enabled the correction of mistakes referenced into protein databases (e.g. bovine vinculin and constitutes valuable evidence for predictions based on genome annotation. Conclusions Elaboration of a reference proteome constitutes the first step in creating a gene expression database dedicated to capillary endothelial cells displaying BBB characteristics. It improves of our knowledge of the BBB and the key proteins in cell structures, cytoskeleton organization, metabolism, detoxification and drug resistance. Moreover, our results emphasize the need for both appropriate experimental design and correct interpretation of proteome datasets.

  17. Loose part monitoring device

    International Nuclear Information System (INIS)

    Nomura, Hiroshi.

    1992-01-01

    The device of the present invention estimates a place where loose parts occur and structural components as the loose parts in a fluid flow channel of a reactor device, to provide information thereof to a plant operator. That is, the device of the present invention comprises (1) a plurality of detectors disposed to each of equipments constituting fluid channels, (2) an abnormal sound sensing device for sensing signals from the detectors, (3) an estimation section for estimating the place where the loose parts occur and the structural components thereof based on the signals sensed by the abnormal sound sensing section, (4) a memory section for storing data of the plant structure necessary for the estimation, and (5) a display section for displaying the result of the estimation. In such a device, the position where the loose parts collide against the plant structural component and the energy thereof are estimated. The dropping path of the loose parts is estimated from the estimation position. Parts to be loose parts in the path are listed up. The parts on the list is selected based on the estimated energy thereby enabling to determine the loose parts. (I.S.)

  18. Large shaft development test plan

    International Nuclear Information System (INIS)

    Krug, A.D.

    1984-03-01

    This test plan proposes the conduct of shaft liner tests as part of the large shaft development test proposed for the Hanford Site in support of the repository development program. The objectives of these tests are to develop techniques for measuring liner alignment (straightness), both construction assembly alignment and downhole cumulative alignment, and to assess the alignment information as a real time feedback to aid the installation procedure. The test plan is based upon installing a 16 foot ID shaft liner into a 20 foot diameter shaft to a depth of 1000 feet. This test plan is considered to be preliminary in that it was prepared as input for the decision to determine if development testing is required in this area. Should the decision be made to proceed with development testing, this test plan shall be updated and revised. 6 refs., 2 figs

  19. Determining of the growth mechanisms in the MBE growth of ternary Cd1-xAxTe (A = Zn, Mn, Hg) compounds. Part I - Methods of analysis of surface processes

    International Nuclear Information System (INIS)

    Sadowski, J.T.

    1999-01-01

    This paper is the first part of an extended abstract of the PhD thesis entitled 'Determining of the growth mechanisms in MBE growth of ternary Cd 1-x A x Te (A = Zn, Mn, Hg) compounds' written on the base of experiments performed in the MBE Lab. in Institute of Vacuum Technology, Warsaw. In that paper, the scientific problems to be solved in thesis are described. Also the analytical techniques (reflection quadrupole mass spectroscopy (REMS), reflection high-energy electron diffraction (RHEED), and laser interferometry (LI)) used in investigation and its implementation to 'in situ' measurements in MBE growth system are depicted. The experiments and extracted scientific results will be presented in the following paper, in next Elektronika issue. (author)

  20. Biostatistics primer: part I.

    Science.gov (United States)

    Overholser, Brian R; Sowinski, Kevin M

    2007-12-01

    Biostatistics is the application of statistics to biologic data. The field of statistics can be broken down into 2 fundamental parts: descriptive and inferential. Descriptive statistics are commonly used to categorize, display, and summarize data. Inferential statistics can be used to make predictions based on a sample obtained from a population or some large body of information. It is these inferences that are used to test specific research hypotheses. This 2-part review will outline important features of descriptive and inferential statistics as they apply to commonly conducted research studies in the biomedical literature. Part 1 in this issue will discuss fundamental topics of statistics and data analysis. Additionally, some of the most commonly used statistical tests found in the biomedical literature will be reviewed in Part 2 in the February 2008 issue.

  1. Application of amino acid type-specific 1H- and 14N-labeling in a 2H-, 15N-labeled background to a 47 kDa homodimer: Potential for NMR structure determination of large proteins

    International Nuclear Information System (INIS)

    Kelly, Mark J.S.; Krieger, Cornelia; Ball, Linda J.; Yu Yihua; Richter, Gerald; Schmieder, Peter; Bacher, Adelbert; Oschkinat, Hartmut

    1999-01-01

    NMR investigations of larger macromolecules (>20 kDa) are severely hindered by rapid 1H and 13C transverse relaxation. Replacement of non-exchangeable protons with deuterium removes many efficient 1H-1H and 1H-13C relaxation pathways. The main disadvantage of deuteration is that many of the protons which would normally be the source of NOE-based distance restraints are removed. We report the development of a novel labeling strategy which is based on specific protonation and 14N-labeling of the residues phenylalanine, tyrosine, threonine, isoleucine and valine in a fully deuterated, 15N-labeled background. This allows the application of heteronuclear half-filters, 15N-editing and 1H-TOCSY experiments to select for particular magnetization transfer pathways. Results from investigations of a 47 kDa dimeric protein labeled in this way demonstrated that the method provides useful information for the structure determination of large proteins

  2. Large forging manufacturing process

    Science.gov (United States)

    Thamboo, Samuel V.; Yang, Ling

    2002-01-01

    A process for forging large components of Alloy 718 material so that the components do not exhibit abnormal grain growth includes the steps of: a) providing a billet with an average grain size between ASTM 0 and ASTM 3; b) heating the billet to a temperature of between 1750.degree. F. and 1800.degree. F.; c) upsetting the billet to obtain a component part with a minimum strain of 0.125 in at least selected areas of the part; d) reheating the component part to a temperature between 1750.degree. F. and 1800.degree. F.; e) upsetting the component part to a final configuration such that said selected areas receive no strains between 0.01 and 0.125; f) solution treating the component part at a temperature of between 1725.degree. F. and 1750.degree. F.; and g) aging the component part over predetermined times at different temperatures. A modified process achieves abnormal grain growth in selected areas of a component where desirable.

  3. Part two

    DEFF Research Database (Denmark)

    Nielsen, Mads Pagh; Kær, Søren Knudsen; Korsgaard, Anders

    2008-01-01

    A novel micro combined heat and power system and a dynamic model thereof were presented in part one of the publication. In the following, the control system and dynamic performance of the system are presented. The model is subjected to a measured consumption pattern of 25 Danish single family...... houses with measurements of heat, power and hot water consumption every 15th minute during one year. Three scenarios are analyzed ranging from heat following only (grid compensation for electricity) to heat and power following with net export of electricity during high and peak load hours. Average...

  4. Effect of temper and hydrogen embrittlement on mechanical properties of 2,25Cr–1Mo steel grades – Application to Minimum Pressurizing Temperature (MPT) issues. Part II: Vintage reactors and MPT determination

    International Nuclear Information System (INIS)

    Pillot, Sylvain; Chauvy, Cédric; Corre, Stéphanie; Coudreuse, Lionel; Gingell, Andrew; Héritier, Déborah; Toussaint, Patrick

    2013-01-01

    Standard and Vanadium-alloyed 2,25Cr–1Mo steel grades (EN 10028-2 12CrMo9-10/ASTM A387 gr. 22 and 13CrMoV9-10/ASTM A542 tp. D) are commonly used for the fabrication of heavy pressure vessels for applications in petroleum refining plants. These reactors are made of heavy plates, forged shells, forged nozzles and fittings. They are subjected to thermal cycles (stop and go) and to severe service conditions (high temperatures and high hydrogen partial pressures). A primary concern for end-users is the definition of the Minimum Pressurizing Temperature (MPT) of the equipment. This temperature is the lowest temperature at which the vessel can be repressurized after shutdown and insures no risk of brittle failure of the containment body. The MPT is defined by fracture mechanics and/or CVN approaches and calculations. This second part of the paper presents the methodology of MPT determination and the particular case of vintage reactors. MPT determination methodology is explained by using a virtual pressure vessel representative of vessels found in petroleum refineries. A special focus is also set on the evolution of embedded defects

  5. Results of preliminary reconnaissance trip to determine the presence of wetlands in wet forest habitats on the Island of Hawaii as part of the Hawaii Geothermal Project, October 1993

    Energy Technology Data Exchange (ETDEWEB)

    Wakeley, J.S.; Sprecher, S.W.; Lichvar, R.

    1994-02-25

    In October 1993, the authors sampled soils, vegetation, and hydrology at eight sites representing a range of substrates, elevations, soil types, and plant community types within rainforest habitats on the Island of Hawaii. Their purpose was to determine whether any of these habitats were wetlands according to the 1987 Corps of Engineers Wetlands Delineation Manual. None of the rainforest habitats they sampled was wetland in its entirety. However, communities established on pahoehoe lava flows contained scattered wetlands in depressions and folds in the lava, where water could accumulate. Therefore, large construction projects, such as that associated with proposed geothermal energy development in the area, have the potential to impact a significant number and/or area of wetlands. To estimate those impacts more accurately, they present a supplementary scope of work and cost estimate for additional sampling in the proposed geothermal project area.

  6. Prediction of crack propagation and arrest in X100 natural gas transmission pipelines with a strain rate dependent damage model (SRDD). Part 2: Large scale pipe models with gas depressurisation

    International Nuclear Information System (INIS)

    Oikonomidis, F.; Shterenlikht, A.; Truman, C.E.

    2014-01-01

    Part 1 of this paper described a specimen for the measurement of high strain rate flow and fracture properties of pipe material and for tuning a strain rate dependent damage model (SRDD). In part 2 the tuned SRDD model is used for the simulation of axial crack propagation and arrest in X100 natural gas pipelines. Linear pressure drop model was adopted behind the crack tip, and an exponential gas depressurisation model was used ahead of the crack tip. The model correctly predicted the crack initiation (burst) pressure, the crack speed and the crack arrest length. Strain rates between 1000 s −1 and 3000 s −1 immediately ahead of the crack tip are predicted, giving a strong indication that a strain rate material model is required for the structural integrity assessment of the natural gas pipelines. The models predict the stress triaxiality of about 0.65 for at least 1 m ahead of the crack tip, gradually dropping to 0.5 at distances of about 5–7 m ahead of the crack tip. Finally, the models predicted a linear drop in crack tip opening angle (CTOA) from about 11−12° at the onset of crack propagation down to 7−8° at crack arrest. Only the lower of these values agree with those reported in the literature for quasi-static measurements. This discrepancy might indicate substantial strain rate dependence in CTOA. - Highlights: • Finite element simulations of 3 burst tests of X100 pipes are detailed. • Strain rate dependent damage model, tuned on small scale X100 samples, was used. • The models correctly predict burst pressure, crack speed and crack arrest length. • The model predicts a crack length dependent critical CTOA. • The strain rate dependent damage model is verified as mesh independent

  7. Large ethics.

    Science.gov (United States)

    Chambers, David W

    2008-01-01

    This essay presents an alternative to the traditional view that ethics means judging individual behavior against standards of right and wrong. Instead, ethics is understood as creating ethical communities through the promises we make to each other. The "aim" of ethics is to demonstrate in our own behavior a credible willingness to work to create a mutually better world. The "game" of ethics then becomes searching for strategies that overlap with others' strategies so that we are all better for intending to act on a basis of reciprocal trust. This is a difficult process because we have partial, simultaneous, shifting, and inconsistent views of the world. But despite the reality that we each "frame" ethics in personal terms, it is still possible to create sufficient common understanding to prosper together. Large ethics does not make it a prerequisite for moral behavior that everyone adheres to a universally agreed set of ethical principles; all that is necessary is sufficient overlap in commitment to searching for better alternatives.

  8. Large-scale computations in fluid mechanics; Proceedings of the Fifteenth Summer Seminar on Applied Mathematics, University of California, La Jolla, CA, June 27-July 8, 1983. Parts 1 and 2

    International Nuclear Information System (INIS)

    Engquist, B.E.; Osher, S.; Somerville, R.C.J.

    1985-01-01

    Papers are presented on such topics as the use of semi-Lagrangian advective schemes in meteorological modeling; computation with high-resolution upwind schemes for hyperbolic equations; dynamics of flame propagation in a turbulent field; a modified finite element method for solving the incompressible Navier-Stokes equations; computational fusion magnetohydrodynamics; and a nonoscillatory shock capturing scheme using flux-limited dissipation. Consideration is also given to the use of spectral techniques in numerical weather prediction; numerical methods for the incorporation of mountains in atmospheric models; techniques for the numerical simulation of large-scale eddies in geophysical fluid dynamics; high-resolution TVD schemes using flux limiters; upwind-difference methods for aerodynamic problems governed by the Euler equations; and an MHD model of the earth's magnetosphere

  9. Large-scale computations in fluid mechanics; Proceedings of the Fifteenth Summer Seminar on Applied Mathematics, University of California, La Jolla, CA, June 27-July 8, 1983. Parts 1 & 2

    Science.gov (United States)

    Engquist, B. E. (Editor); Osher, S. (Editor); Somerville, R. C. J. (Editor)

    1985-01-01

    Papers are presented on such topics as the use of semi-Lagrangian advective schemes in meteorological modeling; computation with high-resolution upwind schemes for hyperbolic equations; dynamics of flame propagation in a turbulent field; a modified finite element method for solving the incompressible Navier-Stokes equations; computational fusion magnetohydrodynamics; and a nonoscillatory shock capturing scheme using flux-limited dissipation. Consideration is also given to the use of spectral techniques in numerical weather prediction; numerical methods for the incorporation of mountains in atmospheric models; techniques for the numerical simulation of large-scale eddies in geophysical fluid dynamics; high-resolution TVD schemes using flux limiters; upwind-difference methods for aerodynamic problems governed by the Euler equations; and an MHD model of the earth's magnetosphere.

  10. Assessment of the radiation risk following from exploitation of Polish brown coals. Part 1. Brown coal in Polish industry; preparation of the method of determining the concentrations of main natural radioisotopes appearing in brown coal and its combustion products

    International Nuclear Information System (INIS)

    Jasinska, M.; Niewiadomski, T.; Schwabenthan, J.

    1982-01-01

    Poland is rich in deposits of brown coal applicable for large-scale industry. These deposits are estimated at about 13.5.10 9 tons. In the near future, one-half of the electric power produced in Poland will be generated by power plants using brown coal. As a result, the yearly burden of the environment in Poland will amount to about 15.10 6 tons of ashes and slag, and about 0.79.10 6 tons of fly ash emitted into the atmosphere. Concentrations of radioactive elements in wastes following from the use of brown coal may in some cases be as much as 12 times higher that occuring from combustion products of lignite coal. Distribution of these wastes to the environment affects the population, through inhalation of fly-ashes, consumption of radioactively contaminated products and through living in dwellings constructed of building materials produced using industrial wastes. In order to determine the concentrations of 226 Ra, 232 Th and 40 K in brown coal and in products of its combustion, the method of identifying these elements through gamma-spectrometry has been prepared. Concentrations of 210 Pb and 210 Po will be determined using the method of electrodeposition on metallic silver, which has been tested in the laboratory. (author)

  11. Plume-related mantle source of super-large rare metal deposits from the Lovozero and Khibina massifs on the Kola Peninsula, Eastern part of Baltic Shield: Sr, Nd and Hf isotope systematics

    Science.gov (United States)

    Kogarko, L. N.; Lahaye, Y.; Brey, G. P.

    2010-03-01

    The two world’s largest complexes of highly alkaline nepheline syenites and related rare metal loparite and eudialyte deposits, the Khibina and Lovozero massifs, occur in the central part of the Kola Peninsula. We measured for the first time in situ the trace element concentrations and the Sr, Nd and Hf isotope ratios by LA-ICP-MS (laser ablation inductively coupled plasma mass spectrometer) in loparite, eudialyte an in some other pegmatitic minerals. The results are in aggreement with the whole rock Sr and Nd isotope which suggests the formation of these superlarge rare metal deposits in a magmatic closed system. The initial Hf, Sr, Nd isotope ratios are similar to the isotopic signatures of OIB indicating depleted mantle as a source. This leads to the suggestion that the origin of these gigantic alkaline intrusions is connected to a deep seated mantle source—possibly to a lower mantle plume. The required combination of a depleted mantle and high rare metal enrichment in the source can be explained by the input of incompatible elements by metasomatising melts/fluids into the zones of alkaline magma generation shortly before the partial melting event (to avoid ingrowth of radiogenic isotopes). The minerals belovite and pyrochlore from the pegmatites are abnormally high in 87Sr /86Sr ratios. This may be explained by closed system isotope evolution as a result of a significant increase in Rb/Sr during the evolution of the peralkaline magma.

  12. Determination of hydrologic properties needed to calculate average linear velocity and travel time of ground water in the principal aquifer underlying the southeastern part of Salt Lake Valley, Utah

    Science.gov (United States)

    Freethey, G.W.; Spangler, L.E.; Monheiser, W.J.

    1994-01-01

    A 48-square-mile area in the southeastern part of the Salt Lake Valley, Utah, was studied to determine if generalized information obtained from geologic maps, water-level maps, and drillers' logs could be used to estimate hydraulic conduc- tivity, porosity, and slope of the potentiometric surface: the three properties needed to calculate average linear velocity of ground water. Estimated values of these properties could be used by water- management and regulatory agencies to compute values of average linear velocity, which could be further used to estimate travel time of ground water along selected flow lines, and thus to determine wellhead protection areas around public- supply wells. The methods used to estimate the three properties are based on assumptions about the drillers' descriptions, the depositional history of the sediments, and the boundary con- ditions of the hydrologic system. These assump- tions were based on geologic and hydrologic infor- mation determined from previous investigations. The reliability of the estimated values for hydro- logic properties and average linear velocity depends on the accuracy of these assumptions. Hydraulic conductivity of the principal aquifer was estimated by calculating the thickness- weighted average of values assigned to different drillers' descriptions of material penetrated during the construction of 98 wells. Using these 98 control points, the study area was divided into zones representing approximate hydraulic- conductivity values of 20, 60, 100, 140, 180, 220, and 250 feet per day. This range of values is about the same range of values used in developing a ground-water flow model of the principal aquifer in the early 1980s. Porosity of the principal aquifer was estimated by compiling the range of porosity values determined or estimated during previous investigations of basin-fill sediments, and then using five different values ranging from 15 to 35 percent to delineate zones in the study area that were assumed to

  13. Dual-Analyte Fluorescent Sensor Based on [5]Helicene Derivative with Super Large Stokes Shift for the Selective Determinations of Cu2+ or Zn2+ in Buffer Solutions and Its Application in a Living Cell.

    Science.gov (United States)

    Sakunkaewkasem, Siwakorn; Petdum, Anuwut; Panchan, Waraporn; Sirirak, Jitnapa; Charoenpanich, Adisri; Sooksimuang, Thanasat; Wanichacheva, Nantanit

    2018-05-10

    A new fluorescent sensor, M201-DPA, based on [5]helicene derivative was utilized as dual-analyte sensor for determination of Cu 2+ or Zn 2+ in different media and different emission wavelengths. The sensor could provide selective and bifunctional determination of Cu 2+ in HEPES buffer containing Triton-X100 and Zn 2+ in Tris buffer/methanol without interference from each other and other ions. In HEPES buffer, M201-DPA demonstrated the selective ON-OFF fluorescence quenching at 524 nm toward Cu 2+ . On the other hand, in Tris buffer/methanol, M201-DPA showed the selective OFF-ON fluorescence enhancement upon the addition of Zn 2+ , which was specified by the hypsochromic shift at 448 nm. Additionally, M201-DPA showed extremely large Stokes shifts up to ∼150 nm. By controlling the concentration of Zn 2+ and Cu 2+ in a living cell, the imaging of a HepG2 cellular system was performed, in which the fluorescence of M201-DPA in the blue channel was decreased upon addition of Cu 2+ and was enhanced in UV channel upon addition of Zn 2+ . The detection limits of M201-DPA for Cu 2+ and Zn 2+ in buffer solutions were 5.6 and 3.8 ppb, respectively. Importantly, the Cu 2+ and Zn 2+ detection limits of the developed sensors were significantly lower than permitted Cu 2+ and Zn 2+ concentrations in drinking water as established by the U.S. EPA and WHO.

  14. THM large spatial-temporal model to simulate the past 2 Ma hydrogeological evolution of Paris Basin including natural tracer transport as part of site characterization for radwaste repository project Cigéo - France

    Science.gov (United States)

    Benabderrahmane, A., Sr.

    2017-12-01

    Hydrogeological site characterization for deep geological high level and intermediate level long lived radioactive waste repository cover a large time scale needed for safety analysis and calculation. Hydrogeological performance of a site relies also on the effects of geodynamic evolution as tectonic uplift, erosion/sedimentation and climate including glaciation on the groundwater flow and solute and heat transfer. Thermo-Hydro-Mechanical model of multilayered aquifer system of Paris Basin is developed to reproduce the present time flow and the natural tracer (Helium) concentration profiles based on the last 2 Ma of geodynamic evolution. Present time geological conceptual model consist of 27 layers at Paris Basin (Triassic-Tertiary) with refinement at project site scale (29 layers from Triassic to Portlandian). Target layers are the clay host formation of Callovo-Oxfrodian age (160 Ma) and the surrounding aquifer layers of Oxfordian and Dogger. Modelled processes are: groundwater flow, heat and solutes (natural tracers) transport, freezing and thawing of groundwater (expansion and retreat of permafrost), deformation of the multilayered aquifer system induced by differential tectonic uplift and the hydro-mechanical stress effect as caused by erosion of the outcropping layers. Numerical simulation considers a period from 2 Ma BP and up to the present. Transient boundary conditions are governed by geodynamic processes: (i) modification of the geometry of the basin and (ii) temperatures along the topography will change according to a series of 15 identical climate cycles with multiple permafrost (glaciation) periods. Numerical model contains 71 layers and 18 million cells. The solution procedure solves three coupled systems of equations, head, temperature and concentrations, by the use of a finite difference method, and by applying extensive parallel processing. The major modelling results related to the processes of importance for site characterization as hydraulic

  15. (segunda parte

    Directory of Open Access Journals (Sweden)

    José María Oliva-Martínez

    2004-01-01

    Full Text Available Este trabajo es la continuación de otro anterior (Oliva, 2004, ambos dedicados al estudio de la importancia del pensamiento analógico en la construcción histórica de la noción de fuerza gravitatoria y del modelo de Sistema Solar. En aquella ocasión analizamos dicho papel durante el período comprendido desde las antiguas civilizaciones hasta llegar a la revolución copernicana con científicos como Copérnico, Gilbert, Kepler o el propio Galileo. En esta segunda parte, se continúa con algunos de los razonamientos analógicos proporcionados desde la vertiente mecanicista, capitaneada por Descartes y desde la tradición subsiguiente que se desarrolló en línea con la utilización del método de la analogía como criterio argumentativo (Huyghens, Hooke, Bernoulli, etc.. Dedicamos asimismo un capítulo aparte a la figura de Newton, quien continúa con dicha tradición en su intento de explicar la naturaleza de la gravitación. Finalmente se procede, a modo de síntesis, a realizar una clasificación de distintos tipos de razonamientos analógicos aportados en el desarrollo histórico en torno a estos temas, estudiando el papel científico y divulgativo de cada uno

  16. Large-scale grid management

    International Nuclear Information System (INIS)

    Langdal, Bjoern Inge; Eggen, Arnt Ove

    2003-01-01

    The network companies in the Norwegian electricity industry now have to establish a large-scale network management, a concept essentially characterized by (1) broader focus (Broad Band, Multi Utility,...) and (2) bigger units with large networks and more customers. Research done by SINTEF Energy Research shows so far that the approaches within large-scale network management may be structured according to three main challenges: centralization, decentralization and out sourcing. The article is part of a planned series

  17. Determination of the Average Native Background and the Light-Induced EPR Signals and their Variation in the Teeth Enamel Based on Large-Scale Survey of the Population

    International Nuclear Information System (INIS)

    Ivannikov, Alexander I.; Khailov, Artem M.; Orlenko, Sergey P.; Skvortsov, Valeri G.; Stepanenko, Valeri F.; Zhumadilov, Kassym Sh.; Williams, Benjamin B.; Flood, Ann B.; Swartz, Harold M.

    2016-01-01

    The aim of the study is to determine the average intensity and variation of the native background signal amplitude (NSA) and of the solar light-induced signal amplitude (LSA) in electron paramagnetic resonance (EPR) spectra of tooth enamel for different kinds of teeth and different groups of people. These values are necessary for determination of the intensity of the radiation-induced signal amplitude (RSA) by subtraction of the expected NSA and LSA from the total signal amplitude measured in L-band for in vivo EPR dosimetry. Variation of these signals should be taken into account when estimating the uncertainty of the estimated RSA. A new analysis of several hundred EPR spectra that were measured earlier at X-band in a large-scale examination of the population of the Central Russia was performed. Based on this analysis, the average values and the variation (standard deviation, SD) of the amplitude of the NSA for the teeth from different positions, as well as LSA in outer enamel of the front teeth for different population groups, were determined. To convert data acquired at X-band to values corresponding to the conditions of measurement at L-band, the experimental dependencies of the intensities of the RSA, LSA and NSA on the m.w. power, measured at both X and L-band, were analysed. For the two central upper incisors, which are mainly used in in vivo dosimetry, the mean LSA annual rate induced only in the outer side enamel and its variation were obtained as 10 ± 2 (SD = 8) mGy y"-"1, the same for X- and L-bands (results are presented as the mean ± error of mean). Mean NSA in enamel and its variation for the upper incisors was calculated at 2.0 ± 0.2 (SD = 0.5) Gy, relative to the calibrated RSA dose-response to gamma radiation measured under non-power saturation conditions at X-band. Assuming the same value for L-band under non-power saturating conditions, then for in vivo measurements at L-band at 25 mW (power saturation conditions), a mean NSA and its

  18. Determination of the Average Native Background and the Light-Induced EPR Signals and their Variation in the Teeth Enamel Based on Large-Scale Survey of the Population.

    Science.gov (United States)

    Ivannikov, Alexander I; Khailov, Artem M; Orlenko, Sergey P; Skvortsov, Valeri G; Stepanenko, Valeri F; Zhumadilov, Kassym Sh; Williams, Benjamin B; Flood, Ann B; Swartz, Harold M

    2016-12-01

    The aim of the study is to determine the average intensity and variation of the native background signal amplitude (NSA) and of the solar light-induced signal amplitude (LSA) in electron paramagnetic resonance (EPR) spectra of tooth enamel for different kinds of teeth and different groups of people. These values are necessary for determination of the intensity of the radiation-induced signal amplitude (RSA) by subtraction of the expected NSA and LSA from the total signal amplitude measured in L-band for in vivo EPR dosimetry. Variation of these signals should be taken into account when estimating the uncertainty of the estimated RSA. A new analysis of several hundred EPR spectra that were measured earlier at X-band in a large-scale examination of the population of the Central Russia was performed. Based on this analysis, the average values and the variation (standard deviation, SD) of the amplitude of the NSA for the teeth from different positions, as well as LSA in outer enamel of the front teeth for different population groups, were determined. To convert data acquired at X-band to values corresponding to the conditions of measurement at L-band, the experimental dependencies of the intensities of the RSA, LSA and NSA on the m.w. power, measured at both X and L-band, were analysed. For the two central upper incisors, which are mainly used in in vivo dosimetry, the mean LSA annual rate induced only in the outer side enamel and its variation were obtained as 10 ± 2 (SD = 8) mGy y -1 , the same for X- and L-bands (results are presented as the mean ± error of mean). Mean NSA in enamel and its variation for the upper incisors was calculated at 2.0 ± 0.2 (SD = 0.5) Gy, relative to the calibrated RSA dose-response to gamma radiation measured under non-power saturation conditions at X-band. Assuming the same value for L-band under non-power saturating conditions, then for in vivo measurements at L-band at 25 mW (power saturation conditions), a mean NSA and its

  19. Large electrostatic accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Jones, C.M.

    1984-01-01

    The increasing importance of energetic heavy ion beams in the study of atomic physics, nuclear physics, and materials science has partially or wholly motivated the construction of a new generation of large electrostatic accelerators designed to operate at terminal potentials of 20 MV or above. In this paper, the author briefly discusses the status of these new accelerators and also discusses several recent technological advances which may be expected to further improve their performance. The paper is divided into four parts: (1) a discussion of the motivation for the construction of large electrostatic accelerators, (2) a description and discussion of several large electrostatic accelerators which have been recently completed or are under construction, (3) a description of several recent innovations which may be expected to improve the performance of large electrostatic accelerators in the future, and (4) a description of an innovative new large electrostatic accelerator whose construction is scheduled to begin next year. Due to time and space constraints, discussion is restricted to consideration of only tandem accelerators.

  20. Large electrostatic accelerators

    International Nuclear Information System (INIS)

    Jones, C.M.

    1984-01-01

    The increasing importance of energetic heavy ion beams in the study of atomic physics, nuclear physics, and materials science has partially or wholly motivated the construction of a new generation of large electrostatic accelerators designed to operate at terminal potentials of 20 MV or above. In this paper, the author briefly discusses the status of these new accelerators and also discusses several recent technological advances which may be expected to further improve their performance. The paper is divided into four parts: (1) a discussion of the motivation for the construction of large electrostatic accelerators, (2) a description and discussion of several large electrostatic accelerators which have been recently completed or are under construction, (3) a description of several recent innovations which may be expected to improve the performance of large electrostatic accelerators in the future, and (4) a description of an innovative new large electrostatic accelerator whose construction is scheduled to begin next year. Due to time and space constraints, discussion is restricted to consideration of only tandem accelerators

  1. Radioecologycal study of {sup 239/240}Pu in Bangka Island and Muria Peninsula: Determination of {sup 239/240}Pu in marine sediment and seawater as part of baseline data collecting for sitting of candidates of first Indonesia NPP

    Energy Technology Data Exchange (ETDEWEB)

    Suseno, Heny, E-mail: henis@batan.go.id [Radioactive Waste Technology Center - The Indonesian National Nuclear Energy Agency (Indonesia); Wisnubroto, Djarot S. [The Indonesian National Nuclear Energy Agency (Indonesia)

    2014-03-24

    Radioisotope Pu-239/240 are alpha emitting nuclides important indicators of radioactive contamination of the marine environment. Global fallout is the main source of plutonium in the marine environment. There are very limited study on {sup 239/240}Pu in Indonesia coastal environments. The data of this radioisotopes is needed for baseline data of nuclear power plant (NPP) site candidates both in Bangka Island and Muria Peninsula. Bottom sediments play an important role in radioecological studies of the marine environment because a large proportion of radioactive substances entering the sea is adsorbed over time onto suspended particulate matter and deposited in sediments. Plutonium is particle reactive and deposited in marine sediment. Radioisotope {sup 239/240}Pu was determinated by alpha spectrometry after radiochemical procedure that was performed in both water and marine sediment from Bangka Island and Muria Peninsula. The sediment baseline of concentration {sup 239/240}Pu in Bangka Island and Muria Peninsula were range from 0.013 to 0.021 Bq.kg{sup −1} and 0.018 to 0.024 Bq.kg{sup −1} respectively. The water baseline concentration this isotope were range from 2.73 to 4.05 mBq.m{sup −3} and 2.98 to 4.50 mBq.m{sup −3}.

  2. Inventory Control of Spare Parts for Operating Nuclear Power plants

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jong-Hyuck; Jang, Se-Jin; Hwang, Eui-Youp; Yoo, Sung-Soo; Yoo, Keun-Bae; Lee, Sang-Guk; Hong, Sung-Yull [Korea Electric Power Research Institute, Taejon (Korea, Republic of)

    2006-07-01

    Inventory control of spare parts plays an increasingly important role in operation management. The trade-off is clear: on one hand a large number of spare parts ties up a large amount of capital, while on the other hand too little inventory may result in extremely costly emergency actions. This is why during the last few decades inventory of spare parts control has been the topics of many publications. Recently management systems such as manufacturing resources planning (MRP) and enterprise resource planning (ERP) have been added. However, most of these contributions have similar theoretical background. This means the concepts and techniques are mainly based on mathematical assumptions and modeling inventory of spare parts situations Nuclear utilities in Korea have several problems to manage the optimum level of spare parts though they used MRP System. Because most of items have long lead time and they are imported from United States, Canada, France and so on. In this paper, we will examine the available inventory optimization models which are applicable to nuclear power plant and then select optimum model and assumptions to make inventory of spare parts strategies. Then we develop the computer program to select and determine optimum level of spare parts which should be automatically controlled by KHNP ERP system. The main contribution of this paper is an inventory of spare parts control model development, which can be applied to nuclear power plants in Korea.

  3. Inventory Control of Spare Parts for Operating Nuclear Power plants

    International Nuclear Information System (INIS)

    Park, Jong-Hyuck; Jang, Se-Jin; Hwang, Eui-Youp; Yoo, Sung-Soo; Yoo, Keun-Bae; Lee, Sang-Guk; Hong, Sung-Yull

    2006-01-01

    Inventory control of spare parts plays an increasingly important role in operation management. The trade-off is clear: on one hand a large number of spare parts ties up a large amount of capital, while on the other hand too little inventory may result in extremely costly emergency actions. This is why during the last few decades inventory of spare parts control has been the topics of many publications. Recently management systems such as manufacturing resources planning (MRP) and enterprise resource planning (ERP) have been added. However, most of these contributions have similar theoretical background. This means the concepts and techniques are mainly based on mathematical assumptions and modeling inventory of spare parts situations Nuclear utilities in Korea have several problems to manage the optimum level of spare parts though they used MRP System. Because most of items have long lead time and they are imported from United States, Canada, France and so on. In this paper, we will examine the available inventory optimization models which are applicable to nuclear power plant and then select optimum model and assumptions to make inventory of spare parts strategies. Then we develop the computer program to select and determine optimum level of spare parts which should be automatically controlled by KHNP ERP system. The main contribution of this paper is an inventory of spare parts control model development, which can be applied to nuclear power plants in Korea

  4. Investing in a Large Stretch Press

    Science.gov (United States)

    Choate, M.; Nealson, W.; Jay, G.; Buss, W.

    1986-01-01

    Press for forming large aluminum parts from plates provides substantial economies. Study assessed advantages and disadvantages of investing in large stretch-forming press, and also developed procurement specification for press.

  5. Development of a large volume injection method using a programmed temperature vaporization injector - gas chromatography hyphenated to ICP-MS for the simultaneous determination of mercury, tin and lead species at ultra-trace levels in natural waters.

    Science.gov (United States)

    Terán-Baamonde, J; Bouchet, S; Tessier, E; Amouroux, D

    2018-04-27

    The current EU legislation lays down Environmental Quality Standards (EQS) for 45 priority substances in surface waters; among them levels for (organo)metallic species of Hg, Sn and Pb are set between ng L -1 (for Hg and Sn) and μg L -1 (for Pb). To date, only a few analytical methods can reach these very restrictive limits and there is thus a need for comprehensive methods able to analyze these species down to these levels in natural waters. The aim of this work was to develop an online automated pre-concentration method using large volume injections with a Programmed Temperature Vaporization (PTV) injector fitted with a sorbent packed liner coupled to GC-ICP-MS to further improve the detection limits associated to this well-established method. The influence of several parameters such as the PTV transfer temperature and time, carrier gas flow rate and amount of packing material was investigated. Finally, the maximum volume injected through single or multiple injection modes was optimized to obtain the best compromise between chromatographic resolution and sensitivity. After optimization, very satisfactory results in terms of absolute and methodological detection limits were achieved, down to the pg L -1 level for all species studied. The potential of the method was exemplified by determining the concentrations of organometallic compounds in unpolluted river waters samples from the Adour river basin (SW France) and results were compared with conventional (splitless) GC-ICP-MS. The strength of this analytical method lies in the low detection limits reached for the simultaneous analysis of a wide group of organometallic compounds, and the potential to transfer this method to other gas chromatographic applications with inherent lower sensitivity. Copyright © 2018 Elsevier B.V. All rights reserved.

  6. Fiber-reinforced concretes with a high fiber volume fraction — a look in future. Can a design determine the fiber amount in concrete in real time in every part of a structure in production?

    Science.gov (United States)

    Tepfers, R.

    2010-09-01

    In near future, when the control of the load-bearing capacity of fiber-only-reinforced concrete members will be safely guaranteed, the deletion of the ordinary continuous steel reinforcing bars might be possible. For the time being, it is difficult to change the fiber amount during the casting with today's techniques. Therefore, the fiber concentration has to be determined by the maximum tensile stress in concrete structural members, resulting in an unnecessary fiber addition in compressed zones. However, if the right amount of fibers could be regulated and added to concrete in real time at the pump outlet, a future vision could be to design and produce a structure by using FEM-controlled equipment. The signals from calculation results could be transmitted to a concrete casting system for addition of a necessary amount of fibers to take care of the actual tensile stresses in the right position in the structure. The casting location could be determined by using a GPS for positioning the pump outlet for targeting the casting location horizontally and a laser vertically. The addition of fibers to concrete at the outlet of a concrete pump and proportioning them there according to the actual needs of the stress situation in a structure, given by a FEM analysis in real time, is a future challenge. The FEM analysis has to be based on material properties of fiber-only-reinforced concrete. This means that the resistance and stiffness of different-strength concrete members with a varying fiber content has to be determined in tests and conveyed to the FEM analysis. The FEM analysis has to be completed before the casting and controlled. Then it can be used as the base for adding a correct amount of fibers to concrete in every part of the structure. Thus, a system for introducing a correct amount of fibers into concrete has to be developed. The fibers have to be added at the outlet of concrete pump. Maybe a system to shotcrete concrete with electronically controlled fiber

  7. Large reservoirs: Chapter 17

    Science.gov (United States)

    Miranda, Leandro E.; Bettoli, Phillip William

    2010-01-01

    Large impoundments, defined as those with surface area of 200 ha or greater, are relatively new aquatic ecosystems in the global landscape. They represent important economic and environmental resources that provide benefits such as flood control, hydropower generation, navigation, water supply, commercial and recreational fisheries, and various other recreational and esthetic values. Construction of large impoundments was initially driven by economic needs, and ecological consequences received little consideration. However, in recent decades environmental issues have come to the forefront. In the closing decades of the 20th century societal values began to shift, especially in the developed world. Society is no longer willing to accept environmental damage as an inevitable consequence of human development, and it is now recognized that continued environmental degradation is unsustainable. Consequently, construction of large reservoirs has virtually stopped in North America. Nevertheless, in other parts of the world construction of large reservoirs continues. The emergence of systematic reservoir management in the early 20th century was guided by concepts developed for natural lakes (Miranda 1996). However, we now recognize that reservoirs are different and that reservoirs are not independent aquatic systems inasmuch as they are connected to upstream rivers and streams, the downstream river, other reservoirs in the basin, and the watershed. Reservoir systems exhibit longitudinal patterns both within and among reservoirs. Reservoirs are typically arranged sequentially as elements of an interacting network, filter water collected throughout their watersheds, and form a mosaic of predictable patterns. Traditional approaches to fisheries management such as stocking, regulating harvest, and in-lake habitat management do not always produce desired effects in reservoirs. As a result, managers may expend resources with little benefit to either fish or fishing. Some locally

  8. Large-scale multimodal transport modelling. Part 1: Demand generation

    CSIR Research Space (South Africa)

    Joubert, JW

    2013-07-01

    Full Text Available agents is generated using existing and available data. Using iterative proportional fitting (IPF), the population is generated for the Nelson Mandela Bay Metropolitan, and includes 24-hour activity chains for both primary activities such as home, work...

  9. FY 1998 Report on development of large-scale wind power generation systems. Part 1. Operational research on large-scale wind power generation systems; 1998 nendo ogata furyoku hatsuden system kaihatsu seika hokokusho. 1. Ogata furyoku hatsuden system no unten kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    The research and development project is implemented for large-scale wind power generation systems, and the FY 1998 results are reported. In the FY 1998, a slip property variable generator is actually mounted on the wind power generator, to conduct various types of demonstration tests. The reliability validation tests include microstructure examinations, fatigue tests and fatigue strength tests to predict residual strength in the blade. It is confirmed that the blade has a sufficient residual strength. The performance validation tests include continuous measurement of power outputs and wind velocities, and analysis of the output fluctuations. The power output performance during winter when the west wind prevails is higher than designed. In the tests for evaluating the characteristics of the system on which a slip property variable generator is mounted, the output smoothing effect is confirmed in a range beyond the rated output. The wind power generation system is continuously operated, to accumulate the operational data for, e.g., capacity factor, operating time rate, and system failure status. The FY 1998 results are 920,000kWh as the output and 21% as capacity factor. The other items investigate include aerodynamic noise reduction countermeasures, fatigue life of the wind turbine blades, economics of wind power generation, and dismantling and reuse of the wind turbines. (NEDO)

  10. Java The Good Parts

    CERN Document Server

    Waldo, Jim

    2010-01-01

    What if you could condense Java down to its very best features and build better applications with that simpler version? In this book, veteran Sun Labs engineer Jim Waldo reveals which parts of Java are most useful, and why those features make Java among the best programming languages available. Every language eventually builds up crud, Java included. The core language has become increasingly large and complex, and the libraries associated with it have grown even more. Learn how to take advantage of Java's best features by working with an example application throughout the book. You may not l

  11. R806 (part 1)

    CERN Multimedia

    CERN PhotoLab

    1976-01-01

    R806 was designed by the BNL-CERN-Syracuse-Yale Collaboration (Bill Willis spokesman) to study large transverse momentum phenomena, and installed in intersection 8 of the ISR. The main detectors were Lithium foil transition radiation detectors to identify electrons and liquid argon calorimeters to measure the energy of the electrons and photons (among the first such calorimeters to be used in an experiment). In part 1 there were two modules, top and bottom of the horizontal beam pipe; the black vertical pipe contains the cryogenics (LN2 and Lar) and is connected to the two modules with the horizontal piping.

  12. Parts of the Whole: Approaching Education as a System

    Directory of Open Access Journals (Sweden)

    Dorothy Wallace

    2009-07-01

    Full Text Available An educational system is a highly coupled complex system of inputs, outputs, sensors and actuators. Using an engineering perspective, this column begins the process of naming and categorizing parts of the system. It then focuses on teachers as one part of a large system, and analyzes the forces that influence how teachers work, and that draw or repel individuals to a teaching career. The growing shortage of qualified teachers can be explained by properties of the system as a whole that determine the context in which teachers do their job.

  13. Large scale model testing

    International Nuclear Information System (INIS)

    Brumovsky, M.; Filip, R.; Polachova, H.; Stepanek, S.

    1989-01-01

    Fracture mechanics and fatigue calculations for WWER reactor pressure vessels were checked by large scale model testing performed using large testing machine ZZ 8000 (with a maximum load of 80 MN) at the SKODA WORKS. The results are described from testing the material resistance to fracture (non-ductile). The testing included the base materials and welded joints. The rated specimen thickness was 150 mm with defects of a depth between 15 and 100 mm. The results are also presented of nozzles of 850 mm inner diameter in a scale of 1:3; static, cyclic, and dynamic tests were performed without and with surface defects (15, 30 and 45 mm deep). During cyclic tests the crack growth rate in the elastic-plastic region was also determined. (author). 6 figs., 2 tabs., 5 refs

  14. Control problems in very large accelerators

    International Nuclear Information System (INIS)

    Crowley-Milling, M.C.

    1985-06-01

    There is no fundamental difference of kind in the control requirements between a small and a large accelerator since they are built of the same types of components, which individually have similar control inputs and outputs. The main difference is one of scale; the large machine has many more components of each type, and the distances involved are much greater. Both of these factors must be taken into account in determining the optimum way of carrying out the control functions. Small machines should use standard equipment and software for control as much as possible, as special developments for small quantities cannot normally be justified if all costs are taken into account. On the other hand, the very great number of devices needed for a large machine means that, if special developments can result in simplification, they may make possible an appreciable reduction in the control equipment costs. It is the purpose of this report to look at the special control problems of large accelerators, which the author shall arbitarily define as those with a length of circumference in excess of 10 km, and point out where special developments, or the adoption of developments from outside the accelerator control field, can be of assistance in minimizing the cost of the control system. Most of the first part of this report was presented as a paper to the 1985 Particle Accelerator Conference. It has now been extended to include a discussion on the special case of the controls for the SSC

  15. Factors Influencing Retention Among Part-Time Clinical Nursing Faculty.

    Science.gov (United States)

    Carlson, Joanne S

    This study sought to determine job characteristics influencing retention of part-time clinical nurse faculty teaching in pre-licensure nursing education. Large numbers of part-time faculty are needed to educate students in the clinical setting. Faculty retention helps maintain consistency and may positively influence student learning. A national sample of part-time clinical nurse faculty teaching in baccalaureate programs responded to a web-based survey. Respondents were asked to identify the primary reason for wanting or not wanting to continue working for a school of nursing (SON). Affinity for students, pay and benefits, support, and feeling valued were the top three reasons given for continuing to work at an SON. Conflicts with life and other job responsibilities, low pay, and workload were the top three reasons given for not continuing. Results from this study can assist nursing programs in finding strategies to help reduce attrition among part-time clinical faculty.

  16. Large-Scale Agriculture and Outgrower Schemes in Ethiopia

    DEFF Research Database (Denmark)

    Wendimu, Mengistu Assefa

    , the impact of large-scale agriculture and outgrower schemes on productivity, household welfare and wages in developing countries is highly contentious. Chapter 1 of this thesis provides an introduction to the study, while also reviewing the key debate in the contemporary land ‘grabbing’ and historical large...... sugarcane outgrower scheme on household income and asset stocks. Chapter 5 examines the wages and working conditions in ‘formal’ large-scale and ‘informal’ small-scale irrigated agriculture. The results in Chapter 2 show that moisture stress, the use of untested planting materials, and conflict over land...... commands a higher wage than ‘formal’ large-scale agriculture, while rather different wage determination mechanisms exist in the two sectors. Human capital characteristics (education and experience) partly explain the differences in wages within the formal sector, but play no significant role...

  17. Intraspecific variability of Holostylis reniformis: concentration of lignans, as determined by maceration and supercritical fluid extraction (SFE-CO{sub 2}), as a function of plant provenance and plant parts

    Energy Technology Data Exchange (ETDEWEB)

    Martins, Gislaine F.; Pereira, Marcos D.P.; Lopes, Lucia M.X., E-mail: lopesxl@iq.unesp.br [Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Araraquara, SP (Brazil). Instituto de Quimica; Silva, Tito da [Universidade Federal do Maranhao (UFMA), Imperatriz, MA (Brazil). Centro de Ciencias Sociais, Saude e Tecnologia; Rosa, Paulo de T. Vieira e; Barbosa, Fernanda P. [Universidade Estadual de Campinas (UNICAMP), SP (Brazil). Instituto de Quimica; Messiano, Gisele B. [Instituto Federal de Sao Paulo, SP (Brazil); Krettli, Antoniana U. [Fundacao Oswaldo Cruz (FIOCRUZ), Belo Horizonte, MG (Brazil). Instituto Rene Rachou

    2014-04-15

    Maceration and supercritical fluid extraction were used to prepare extracts from parts of plants (Holostylis reniformis) collected in two different regions of Brazil. {sup 1}H NMR, HPLC-DAD-ESI/MS, HPLC-DAD, GC-MS, and chemometric techniques were used to analyse lignans in the extracts and showed that yields of SFE-CO{sub 2} were less than or equal to those of hexane maceration extracts. These analyses, in conjunction with the concentrations of aliphatic hydrocarbons, fatty acids and their methyl and ethyl derivatives in the extracts, also allowed the chemical composition of parts and provenance of the plant to be differentiated. (author)

  18. Intraspecific variability of Holostylis reniformis: concentration of lignans, as determined by maceration and supercritical fluid extraction (SFE-CO2), as a function of plant provenance and plant parts

    International Nuclear Information System (INIS)

    Martins, Gislaine F.; Pereira, Marcos D.P.; Lopes, Lucia M.X.; Krettli, Antoniana U.

    2014-01-01

    Maceration and supercritical fluid extraction were used to prepare extracts from parts of plants (Holostylis reniformis) collected in two different regions of Brazil. 1 H NMR, HPLC-DAD-ESI/MS, HPLC-DAD, GC-MS, and chemometric techniques were used to analyse lignans in the extracts and showed that yields of SFE-CO 2 were less than or equal to those of hexane maceration extracts. These analyses, in conjunction with the concentrations of aliphatic hydrocarbons, fatty acids and their methyl and ethyl derivatives in the extracts, also allowed the chemical composition of parts and provenance of the plant to be differentiated. (author)

  19. Large orders in strong-field QED

    Energy Technology Data Exchange (ETDEWEB)

    Heinzl, Thomas [School of Mathematics and Statistics, University of Plymouth, Drake Circus, Plymouth PL4 8AA (United Kingdom); Schroeder, Oliver [Science-Computing ag, Hagellocher Weg 73, D-72070 Tuebingen (Germany)

    2006-09-15

    We address the issue of large-order expansions in strong-field QED. Our approach is based on the one-loop effective action encoded in the associated photon polarization tensor. We concentrate on the simple case of crossed fields aiming at possible applications of high-power lasers to measure vacuum birefringence. A simple next-to-leading order derivative expansion reveals that the indices of refraction increase with frequency. This signals normal dispersion in the small-frequency regime where the derivative expansion makes sense. To gain information beyond that regime we determine the factorial growth of the derivative expansion coefficients evaluating the first 82 orders by means of computer algebra. From this we can infer a nonperturbative imaginary part for the indices of refraction indicating absorption (pair production) as soon as energy and intensity become (super)critical. These results compare favourably with an analytic evaluation of the polarization tensor asymptotics. Kramers-Kronig relations finally allow for a nonperturbative definition of the real parts as well and show that absorption goes hand in hand with anomalous dispersion for sufficiently large frequencies and fields.

  20. 76 FR 10671 - Assessments, Large Bank Pricing

    Science.gov (United States)

    2011-02-25

    ... 327 Assessments, Large Bank Pricing; Final Rule #0;#0;Federal Register / Vol. 76 , No. 38 / Friday... Part 327 RIN 3064-AD66 Assessments, Large Bank Pricing AGENCY: Federal Deposit Insurance Corporation..., (202) 898-6796; Lisa Ryu, Chief, Large Bank Pricing Section, Division of Insurance and Research, (202...

  1. Determination of elemental impurities in polymer materials of electrical cables for use in safety systems of nuclear power plants and for data transfer in the Large Hadron Collider by instrumental neutron activation analysis

    Czech Academy of Sciences Publication Activity Database

    Kučera, Jan; Cabalka, M.; Ferencei, Jozef; Kubešová, Marie; Strunga, Vladimír

    2016-01-01

    Roč. 309, č. 3 (2016), s. 1341-1348 ISSN 0236-5731 R&D Projects: GA TA ČR TA02010218; GA MŠk(CZ) LM2011019 Institutional support: RVO:61389005 Keywords : instrumental neutron activation analysis * polymer materials * undesired elements * nuclear power plant * Large Hadron Collider Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 1.282, year: 2016

  2. Job sharing. Part 1.

    Science.gov (United States)

    Anderson, K; Forbes, R

    1989-01-01

    This article is the first of a three part series discussing the impact of nurses job sharing at University Hospital, London, Ontario. This first article explores the advantages and disadvantages of job sharing for staff nurses and their supervising nurse manager, as discussed in the literature. The results of a survey conducted on a unit with a large number of job sharing positions, concur with literature findings. The second article will present the evaluation of a pilot project in which two nurses job share a first line managerial position in the Operating Room. The third article will relate the effects of job sharing on women's perceived general well being. Job sharing in all areas, is regarded as a positive experience by both nurse and administrators.

  3. A Cost-Effective Two-Part Experiment for Teaching Introductory Organic Chemistry Techniques

    Science.gov (United States)

    Sadek, Christopher M.; Brown, Brenna A.; Wan, Hayley

    2011-01-01

    This two-part laboratory experiment is designed to be a cost-effective method for teaching basic organic laboratory techniques (recrystallization, thin-layer chromatography, column chromatography, vacuum filtration, and melting point determination) to large classes of introductory organic chemistry students. Students are exposed to different…

  4. Electroweak baryogenesis, large Yukawas and dark matter

    International Nuclear Information System (INIS)

    Provenza, Alessio; Quiros, Mariano; Ullio, Piero

    2005-01-01

    It has recently been shown that the electroweak baryogenesis mechanism is feasible in Standard Model extensions containing extra fermions with large Yukawa couplings. We show here that the lightest of these fermionic fields can naturally be a good candidate for cold dark matter. We find regions in the parameter space where the thermal relic abundance of this particle is compatible with the dark matter density of the Universe as determined by the WMAP experiment. We study direct and indirect dark matter detection for this model and compare with current experimental limits and prospects for upcoming experiments. We find, contrary to the standard lore, that indirect detection searches are more promising than direct ones, and they already exclude part of the parameter space

  5. A new methodology of experimental investigations of the generalized matrix effect. Part 4. The influence of anions on the spectrophotometric determination of zinc and cadmium with 1-(2-pyridylazo)-2-naphthol

    International Nuclear Information System (INIS)

    Plesinska, M.; Rokosz, A.

    1981-01-01

    Using the methodology of investigation of the so called matrix effect the interferences in the extraction-spectrophotometric determination of zinc and cadmium with the PAN reagent caused by thiocyanates, iodides and sulphates have been evaluated. Basing on the results of the determinations made on the standard solutions, which compositions were defined by the composite rotatable design for the three factors (concentrations of: KSCN, KJ and K 2 SO 4 ), the polynomial models of absorbance of the chloroform phase as the function of the concentrations of the accompanying salts have been formulated. The results of earlier monofactorial investigations of the influence of the salts tested on the determination of zinc and cadmium have been confirmed. Besides, for the first time the significant second order effects including interactions between different anions have been observed. (author)

  6. Large area and flexible electronics

    CERN Document Server

    Caironi, Mario

    2015-01-01

    From materials to applications, this ready reference covers the entire value chain from fundamentals via processing right up to devices, presenting different approaches to large-area electronics, thus enabling readers to compare materials, properties and performance.Divided into two parts, the first focuses on the materials used for the electronic functionality, covering organic and inorganic semiconductors, including vacuum and solution-processed metal-oxide semiconductors, nanomembranes and nanocrystals, as well as conductors and insulators. The second part reviews the devices and applicatio

  7. Large components dismantlement flow chart in the United States

    International Nuclear Information System (INIS)

    Szilagyi, Andrew

    2012-01-01

    The beginning steps are identical for large or regular components. The starting point of this flowchart assumes that it has already been determined the component has been categorized as waste. The first step is to make sure that all components are handled safely, that ALARA is followed, that any security concerns are managed, and that the dismantlement cost or any other cost is constantly reviewed. After this, the process knowledge and acceptable knowledge should be reviewed; this will help in the following step which is characterization with non-destructive assay. At this point, the project manager is presented with the first three alternatives which will determine the path to follow: Low level waste (LLW) disposal flowchart, part 1 to 3 , Transuranic waste (TRU) disposal flowchart, part 1 and 2 , or High level waste (HLW) disposal flowchart

  8. Mapping Forage Resources Using Earth Observation Data: A Case Study to Assess the Relationship Between Herbaceous and Woody Cover Components as Determinants of Large Herbivore Distribution in Sub-Saharan Africa

    Science.gov (United States)

    Hanan, N. P.; Kahiu, M. N.

    2016-12-01

    Grazing systems are important for survival of humans, livestock and wildlife in Sub-Saharan Africa (SSA). They are mainly found in the arid and semi-arid regions and are characterized by naturally occurring tree-grass vegetation mixtures ("savannas"), low and erratic rainfall, low human populations, and scanty water resources. Due to the scarce population and perceived low resource base they have been marginalized for decades, if not centuries. However, their economic and environmental significance, particularly their role as foraging lands for livestock and wildlife cannot be underrated. SSA natural grazing systems comprise a significant source of livelihood, where millions of people depend on pastoralism as a source of food and income. Further, the African savannas support diverse flora and charismatic large herbivore and carnivore guilds. The above considerations motivate a more detailed study of the composition, temporal and spatial variability of foraging resources in SSA arid and semi-arid regions. We have therefore embarked on a research to map Africa foraging resources by partitioning MODIS total leaf area index (LAIA) time series into its woody (LAIW) and herbaceous (LAIH) constituents as proxies for grazing and browsing resources, respectively. Using the portioned LAI estimates we will develop a case study to assess how forage resources affect distribution and abundance of large herbivores in Africa. In our case study we explore two separate but related hypothesis: i) small and medium sized mammalian herbivore numbers will peak at intermediate biomass (LAIH for grazers and LAIW for browsers), since they optimize on forage quantity and quality. Conversely, large-body mammalian herbivores have the ability to process high quantity-low quality food, hence, we hypothesize that ii) larger herbivores will tend to be more common in high forage areas irrespective of forage quality. We will use LAIH and LAIW retrievals to compute annual average leaf area duration

  9. Rickets: Part I.

    Science.gov (United States)

    Shore, Richard M; Chesney, Russell W

    2013-01-01

    Rickets is characterized by impaired mineralization and ossification of the growth plates of growing children caused by a variety of disorders, the most frequent of which is nutritional deficiency of vitamin D. Despite ample knowledge of its etiology and the availability of cost-effective methods of preventing it, vitamin D deficiency rickets remains a significant problem in developing and developed countries. This two-part review covers the history, etiology, pathophysiology and clinical and radiographical findings of vitamin D deficiency rickets. Other less frequent causes of rickets and some of the disorders entering into the differential diagnoses of rickets are also considered. Controversial issues surrounding vitamin D deficiency include determination of what constitutes vitamin D sufficiency and the potential relationship between low levels of vitamin D metabolites in many individuals and unexplained fractures in infants.

  10. Stochastic model of forecasting spare parts demand

    Directory of Open Access Journals (Sweden)

    Ivan S. Milojević

    2012-01-01

    spare part has its own failure intensity; therefore, it is necessary to conduct a complete procedure for each part. If the average number of components of a complex asset were about 5000, along with the existence of a large number of resources, the forecasting by the trend extrapolating would practically require the newest information technologies. However, the analysis shows that in most cases 80-90% of component parts have a longer life than the asset itself. In addition, it is shown that during the life of the asset, these components do not fail, and that 10-15% of component parts have only rare failures (post optimal analysis of spare parts normative or do not show any failing tendency meaning that failures are random. This procedure remains to be applied to 2-4% of component parts. It does not present a significant problem due to the process automation. This model enables us to determine the parts to which the trend extrapolation procedure should be applied. Forecast is obtained by the use of the second model to existing data. The trend extrapolation forecast or any other kind of forecast does not need to be done for those spare parts for which the long time forecast is close to zero. Provision of spare parts for the maintenance system considering the range, quantity, time and place is crucial for successful functioning of the maintenance system and ultimately for the accuracy of material resources. On the other hand, stocks of spare parts are costly and required to be reduced. Costs need to be minimized while ensuring the successful functioning of the maintenance system.

  11. Joint studies on large CANDU

    International Nuclear Information System (INIS)

    Lee, Ikhwan; Yu, S. K. W.

    1994-01-01

    from economic, safety and strategic viewpoints. A large number of research and development programs are now in place at AECL and KAERI that will permit substantial improvements to be realized in the next generation of CANDU okabts, Furthermore, opportunities exist for engineered improvements based on the research and development in advancing the generic CANDU Technology. Final Large CANDU joint study report with technical deliverables will be issued 1994 October. Phase 2 R and D program of the joint studies will be determined this year and implemented in next year. CANDU neutron economy permits versatility in choices of fuel cycles. This allows a utility to choose fuel cycle options for lower fuelling cost, better security of supply, and ultimately for much lower spent-fuel volume, than with PWR's alone. To meet Korea's strategic requirements, CANDU should be an integral part of the electricity supply mix.

  12. Analytical methods for determination of radiochemical and radionuclidic purity of radiopharmaceuticals containing sup(99m)Tc and sup(113m)In. Part of a coordinated programme on radiopharmaceuticals

    International Nuclear Information System (INIS)

    Galatzeanu, I.

    1974-01-01

    The obtained results on radiochemical and radionuclidic purities determination of sup(99m)Tc and sup(113m)In-radiopharmaceuticals proved to be a good tool for small hospital units and laboratories in satisfying their duty to improve the quality control. The complicated behaviour of technetium in aqueous solutions during the preparation of radiopharmaceuticals, needs further research work to elucidate the mechanisms of interaction of reduced species with media and their disproportionation

  13. Dual color chromogenic in situ hybridization for determination of HER2 status in breast cancer: a large comparative study to current state of the art fluorescence in situ hybridization

    Directory of Open Access Journals (Sweden)

    Mollerup Jens

    2012-02-01

    Full Text Available Abstract Background Chromogenic in situ hybridization (CISH is fast becoming a well established technique for easy and sensitive determination of HER2 gene status in breast cancer. However, for the chromogenic method to achieve status as a safe and reliable technique, the method needs to be validated against already known and validated FISH techniques. Methods Here it is reported from a comparative study where HER2 gene status obtained by HER2 CISH pharmDx™ Kit was compared to HER2 gene status obtained by the FDA approved HER2 FISH pharmDx™ Kit and the PathVysion HER-2 DNA probe Kit. The study included 365 formalin fixed and paraffin-embedded invasive breast cancer tissue specimens collected consecutively at a US reference laboratory. Results The data obtained revealed an overall HER2 status concordance of approximately 98% for comparisons of HER2 CISH pharmDx™ Kit to both HER2 FISH pharmDx™ Kit and PathVysion HER-2 DNA Probe Kit. Conclusions The concordance between results obtained using the recently FDA approved HER2 CISH pharmDx™ Kit with previously FDA approved FISH techniques for HER2 gene status determination indicate that the HER2 CISH pharmDx™ Kit is a reliable chromogenic alternative to fluorescence-based methods.

  14. Dual color chromogenic in situ hybridization for determination of HER2 status in breast cancer: a large comparative study to current state of the art fluorescence in situ hybridization

    Science.gov (United States)

    2012-01-01

    Background Chromogenic in situ hybridization (CISH) is fast becoming a well established technique for easy and sensitive determination of HER2 gene status in breast cancer. However, for the chromogenic method to achieve status as a safe and reliable technique, the method needs to be validated against already known and validated FISH techniques. Methods Here it is reported from a comparative study where HER2 gene status obtained by HER2 CISH pharmDx™ Kit was compared to HER2 gene status obtained by the FDA approved HER2 FISH pharmDx™ Kit and the PathVysion HER-2 DNA probe Kit. The study included 365 formalin fixed and paraffin-embedded invasive breast cancer tissue specimens collected consecutively at a US reference laboratory. Results The data obtained revealed an overall HER2 status concordance of approximately 98% for comparisons of HER2 CISH pharmDx™ Kit to both HER2 FISH pharmDx™ Kit and PathVysion HER-2 DNA Probe Kit. Conclusions The concordance between results obtained using the recently FDA approved HER2 CISH pharmDx™ Kit with previously FDA approved FISH techniques for HER2 gene status determination indicate that the HER2 CISH pharmDx™ Kit is a reliable chromogenic alternative to fluorescence-based methods. PMID:22333181

  15. Grinding Parts For Automatic Welding

    Science.gov (United States)

    Burley, Richard K.; Hoult, William S.

    1989-01-01

    Rollers guide grinding tool along prospective welding path. Skatelike fixture holds rotary grinder or file for machining large-diameter rings or ring segments in preparation for welding. Operator grasps handles to push rolling fixture along part. Rollers maintain precise dimensional relationship so grinding wheel cuts precise depth. Fixture-mounted grinder machines surface to quality sufficient for automatic welding; manual welding with attendant variations and distortion not necessary. Developed to enable automatic welding of parts, manual welding of which resulted in weld bead permeated with microscopic fissures.

  16. VULNERABILITY OF PART TIME EMPLOYEES

    Directory of Open Access Journals (Sweden)

    Raluca Dimitriu

    2015-11-01

    Full Text Available The employee who concluded a part-time contract is the employee whose normal working hours, calculated weekly or as monthly average, is lower than the number of normal working hours of a comparable full-time employee. Part-time workers generally have the same legal status as full time workers. In fact, the vulnerability of this category of workers is not necessarily legal but rather economic: income - in proportion to the work performed, may be insufficient to cover the needs of living. However, such vulnerability may also have a certain cultural component: in some societies, professional identity is determined by the length of working hours. Also, part time work may hide many types of indirect discrimination.As a result, the part-time contract requires more than a protective legislation: it requires a strategy. This paper proposes a number of milestones of such a strategy, as well as some concrete de lege ferenda proposals.

  17. In-vitro use of radiominerals to determine mineral imbalances in farm animals. Part of a coordinated programme on the use of isotopes to diagnose moderate mineral imbalances in farm animals

    International Nuclear Information System (INIS)

    Goksoy, K.

    1981-01-01

    This research programme involved the use of in vitro radioisotopic procedures as well as stable element analysis and enzyme determinations to evaluate selenium, copper and zinc deficiency states in sheep in Turkey. Uptake of radioactive selenium by red blood cells was effective in determining the selenium status of sheep. Animals on a selenium deficient diet had red cell selenium uptakes significantly greater than those of sheep fed normal levels of selenium. When sheep on a selenium deficient diet were tested and then supplemented with selenium for several weeks, the red cell uptakes of radioselenium after supplementation were significantly less than before supplementation. A similar technique was used to study the zinc status of sheep. Uptake of radioactive zinc by red cells was greater in deficient sheep than in zinc-supplemented animals. Zinc deficient sheep also had lower serum zinc levels than in supplemented animals, and alkaline phosphatase activity levels. Assays of erythrocyte uptake, using a scintillation counter may be useful in the absence of equipment for total mineral analysis or enzyme assays. In another study the serum copper levels of sheep of different genetic types were compared to serum ceruloplasmin levels and to the incidence of enzootic ataxia in offspring of these animals. A definite correlation was found between haemoglobulin type, serum copper level and ceruloplasmin level. Comparisons of these parameters in sheep with copper and molybdenum levels in forage samples indicated that copper deficiency in sheep in Turkey is apparently a secondary copper deficiency due to high levels of molybdenum in forage

  18. Simplified method for the determination of strontium-90 in large amounts of bone-ash; Methode simplifiee de dosage du strontium 90 sur des quantites importantes de cendres d'os

    Energy Technology Data Exchange (ETDEWEB)

    Patti, F; Jeanmaire, L [Commissariat a l' Energie Atomique, Fontenay-aux-roses (France). Centre d' Etudes Nucleaires

    1966-06-01

    The principle of the determination is based on a 3-step process: 1) concentrating the strontium by attacking the ash with nitric acid; 2) elimination of residual phosphoric ions by a double precipitation of strontium oxalate; and 3) extraction of yttrium 90, counted in the oxalate form. The advantages of the method: -) using simple techniques it makes it possible to process 50 g of ash; -) the initial concentration of strontium considerably reduces the volume of the solutions as well as the size of precipitates handled. Fuming nitric acid is used in a specially designed burette. (authors) [French] Le principe du dosage repos sur un procede en 3 etapes: 1) Concentration du strontium par une attaque nitrique des cendres; 2) Elimination des ions phosphoriques restants par une double precipitation de l'oxalate de strontium. 3) Extraction de l'yttrium 90, compte sous forme d'oxalate. Interet de la methode: dans des conditions techniques simples, elle permet le traitement de 50 g de cendres d'os; la concentration initiale du strontium reduit notablement le volume des solutions ainsi que l'importance des precipites manipules. L'acide nitrique fumant est utilise par l'intermediaire d'une burette specialement concue a cet effet.

  19. Zirconia coated stir bar sorptive extraction combined with large volume sample stacking capillary electrophoresis-indirect ultraviolet detection for the determination of chemical warfare agent degradation products in water samples.

    Science.gov (United States)

    Li, Pingjing; Hu, Bin; Li, Xiaoyong

    2012-07-20

    In this study, a sensitive, selective and reliable analytical method by combining zirconia (ZrO₂) coated stir bar sorptive extraction (SBSE) with large volume sample stacking capillary electrophoresis-indirect ultraviolet (LVSS-CE/indirect UV) was developed for the direct analysis of chemical warfare agent degradation products of alkyl alkylphosphonic acids (AAPAs) (including ethyl methylphosphonic acid (EMPA) and pinacolyl methylphosphonate (PMPA)) and methylphosphonic acid (MPA) in environmental waters. ZrO₂ coated stir bar was prepared by adhering nanometer-sized ZrO₂ particles onto the surface of stir bar with commercial PDMS sol as adhesion agent. Due to the high affinity of ZrO₂ to the electronegative phosphonate group, ZrO₂ coated stir bars could selectively extract the strongly polar AAPAs and MPA. After systematically optimizing the extraction conditions of ZrO₂-SBSE, the analytical performance of ZrO₂-SBSE-CE/indirect UV and ZrO₂-SBSE-LVSS-CE/indirect UV was assessed. The limits of detection (LODs, at a signal-to-noise ratio of 3) obtained by ZrO₂-SBSE-CE/indirect UV were 13.4-15.9 μg/L for PMPA, EMPA and MPA. The relative standard deviations (RSDs, n=7, c=200 μg/L) of the corrected peak area for the target analytes were in the range of 6.4-8.8%. Enhancement factors (EFs) in terms of LODs were found to be from 112- to 145-fold. By combining ZrO₂ coating SBSE with LVSS as a dual preconcentration strategy, the EFs were magnified up to 1583-fold, and the LODs of ZrO₂-SBSE-LVSS-CE/indirect UV were 1.4, 1.2 and 3.1 μg/L for PMPA, EMPA, and MPA, respectively. The RSDs (n=7, c=20 μg/L) were found to be in the range of 9.0-11.8%. The developed ZrO₂-SBSE-LVSS-CE/indirect UV method has been successfully applied to the analysis of PMPA, EMPA, and MPA in different environmental water samples, and the recoveries for the spiked water samples were found to be in the range of 93.8-105.3%. Copyright © 2012 Elsevier B.V. All rights reserved.

  20. Development of rapid universal method for determination of Cs-137 in different environmental samples by means of inorganic ion exchangers. Part of a coordinated programme on radiological and environmental protection studies in the Danube river catchment area

    International Nuclear Information System (INIS)

    Radicheva, M.

    1983-02-01

    Using three synthetic inorganic ion exchangers of the same type - X 2 [YFe (CN) 6 ] (when X=alkali metal, Y=transition metal) one simple and universal rapid method for determination of Cs-137 in environmental samples was developed. The investigations carried out on synthesis, next preparation and practical use in routine analysis showed that K[CoFe(CN) 6 ] (abbr.KCFC-II) is the most suitable for analysis of low level activities of Cs-137 in different environmental samples. The optimum conditions for routine use of KCFC-II in different separation schemes were found. Repeated analysis of Cs-137 in different environmental samples as well as analysis of IAEA-Reference Materials using our rapid and one classical method showed good agreement of the results. The proposed rapid method can be used in emergency situations and in routine radiation control. (author)