WorldWideScience

Sample records for laps pesuveega alla

  1. Dal caos... alla coscienza

    CERN Document Server

    Prattico, Franco

    1989-01-01

    Attraverso i domini della fisica, della genetica e della biologia, fino alle neuroscienze, alla ricerca dei percorsi che hanno portato alla nascita del cervello umano : frutto di una singolare serie casuale o di una necessità inscritta nelle leggi del Cosmo?

  2. [Sample German LAPS.

    Science.gov (United States)

    Rosenthal, Bianca

    Four learning activity packages (LAPS) for use in secondary school German programs contain instructional materials which enable students to improve their basic linguistic skills. The units include: (1) "Grusse," (2) "Ich Heisse...Namen," (3) "Tune into Your Career: Business Correspondence 'Auf Deutch'," and (4) "Understanding German Culture."…

  3. The LapSlapper

    DEFF Research Database (Denmark)

    Andresen, Mads Stenhøj; Bach, Morten; Kristensen, Kristian Ross

    2010-01-01

    The LapSlapper is an inexpensive and low-technology percussive instrument with a digital interface. In a tactile and embodied manner it allows enhanced control and promotes expressive creativity when operating with percussive elements in digital environments. By using piezo-microphones, mounted...

  4. Lap belt injuries in children.

    LENUS (Irish Health Repository)

    McGrath, N

    2010-07-01

    The use of adult seat belts without booster seats in young children may lead to severe abdominal, lumbar or cervical spine and head and neck injuries. We describe four characteristic cases of lap belt injuries presenting to a tertiary children\\'s hospital over the past year in addition to a review of the current literature. These four cases of spinal cord injury, resulting in significant long-term morbidity in the two survivors and death in one child, arose as a result of lap belt injury. These complex injuries are caused by rapid deceleration characteristic of high impact crashes, resulting in sudden flexion of the upper body around the fixed lap belt, and consequent compression of the abdominal viscera between the lap belt and spine. This report highlights the dangers of using lap belts only without shoulder straps. Age-appropriate child restraint in cars will prevent these injuries.

  5. Alla scoperta della crittografia quantistica

    CERN Document Server

    Filoramo, Eva; Pasquero, Claudia

    2006-01-01

    La crittografia si sviluppa e perfeziona per rispondere all'esigenza di segretezza nella trasmissione delle informazioni. La crittografia quantistica consente, al contrario di quella correntemente usata, di inviare messaggi che non potranno essere decifrati e di vanificare al massimo i tentativi di una loro intercettazione. Partendo dalla storia dei codici segreti, il libro affronta gli sviluppi pertinenti della teoria quantistica, per approdare infine alla più avanzata ricerca scientifica e tecnologica. Lo scopo è quello di richiamare l'attenzione su un tema le cui applicazioni pratiche coprono molti settori d'interesse strategico e sono destinate, nel prossimo futuro, a rivoluzionare i metodi di scambio delle informazioni.

  6. Dall’estetica alla teoria. Note sulla transestetica della letteratura

    Directory of Open Access Journals (Sweden)

    Lorenzo Oropallo

    2012-12-01

    Full Text Available Come ha messo in rilievo Paul De Man, la teoria della letteratura nasce insieme alla letteratura stessa, dunque a partire dal primo romanticismo tedesco e la sua riflessione intorno alla natura dell'arte. In questo senso, la teoria letteraria non si oppone alla pratica della scrittura, ma alla sua estetica, che quindi è necessario superare.

  7. Sequential lineup laps and eyewitness accuracy.

    Science.gov (United States)

    Steblay, Nancy K; Dietrich, Hannah L; Ryan, Shannon L; Raczynski, Jeanette L; James, Kali A

    2011-08-01

    Police practice of double-blind sequential lineups prompts a question about the efficacy of repeated viewings (laps) of the sequential lineup. Two laboratory experiments confirmed the presence of a sequential lap effect: an increase in witness lineup picks from first to second lap, when the culprit was a stranger. The second lap produced more errors than correct identifications. In Experiment 2, lineup diagnosticity was significantly higher for sequential lineup procedures that employed a single versus double laps. Witnesses who elected to view a second lap made significantly more errors than witnesses who chose to stop after one lap or those who were required to view two laps. Witnesses with prior exposure to the culprit did not exhibit a sequential lap effect.

  8. Additive manufacturing of tools for lapping glass

    Science.gov (United States)

    Williams, Wesley B.

    2013-09-01

    Additive manufacturing technologies have the ability to directly produce parts with complex geometries without the need for secondary processes, tooling or fixtures. This ability was used to produce concave lapping tools with a VFlash 3D printer from 3D Systems. The lapping tools were first designed in Creo Parametric with a defined constant radius and radial groove pattern. The models were converted to stereolithography files which the VFlash used in building the parts, layer by layer, from a UV curable resin. The tools were rotated at 60 rpm and used with 120 grit and 220 grit silicon carbide lapping paste to lap 0.750" diameter fused silica workpieces. The samples developed a matte appearance on the lapped surface that started as a ring at the edge of the workpiece and expanded to the center. This indicated that as material was removed, the workpiece radius was beginning to match the tool radius. The workpieces were then cleaned and lapped on a second tool (with equivalent geometry) using a 3000 grit corundum aluminum oxide lapping paste, until a near specular surface was achieved. By using lapping tools that have been additively manufactured, fused silica workpieces can be lapped to approach a specified convex geometry. This approach may enable more rapid lapping of near net shape workpieces that minimize the material removal required by subsequent polishing. This research may also enable development of new lapping tool geometry and groove patterns for improved loose abrasive finishing.

  9. Il rumore elettrico Dalla fisica alla progettazione

    CERN Document Server

    Pallottino, Giovanni Vittorio

    2011-01-01

    L’opera fornisce una trattazione chiara, agile ed essenziale, ma completa, del rumore elettrico, argomento considerato generalmente oscuro e specialistico. Molto più breve (circa 275mila battute) dei testi attualmente disponibili. Il contenuto copre gli aspetti essenziali della matematica e della fisica del rumore (termico, shot. 1/f, …), e della sua rappresentazione nei circuiti. Discute quindi il rumore nei dispositivi passivi e attivi, e introduce i criteri di progettazione a basso rumore. Affronta infine brevemente questioni quali l’estrazione del segnale dal rumore e gli impieghi utili del rumore. L’attenzione è generalmente rivolta alla strumentazione fisica a bassa frequenza, in relazione alla pluridecennale esperienza specifica dell’autore. Si tratta di una estensione delle dispense, utilizzate per anni, di un corso universitario. Pertanto la trattazione è fortemente didattica, con particolare attenzione a rimuovere ambiguità e incertezze, discutendo il materiale in termini fisici intuit...

  10. Ad populum. Parlare alla pancia: retoriche del populismo in Europa

    Directory of Open Access Journals (Sweden)

    Yulia Ivanova

    2016-12-01

    Full Text Available Recensiamo il libro Ad populum. Parlare alla pancia: retorica del populismo in Europa. Eds. Bruno Capaci e Giuditta Spassini. Bologna: I libri di Emil di Odoya srl., 2016. Stampa. Review of Ad populum. Parlare alla pancia: retorica del populismo in Europa. Eds. Bruno Capaci and Giuditta Spassini. Bologna: I libri di Emil di Odoya srl., 2016. Print

  11. Even between-lap pacing despite high within-lap variation during mountain biking.

    Science.gov (United States)

    Martin, Louise; Lambeth-Mansell, Anneliese; Beretta-Azevedo, Liane; Holmes, Lucy A; Wright, Rachel; St Clair Gibson, Alan

    2012-09-01

    Given the paucity of research on pacing strategies during competitive events, this study examined changes in dynamic high-resolution performance parameters to analyze pacing profiles during a multiple-lap mountain-bike race over variable terrain. A global-positioning-system (GPS) unit (Garmin, Edge 305, USA) recorded velocity (m/s), distance (m), elevation (m), and heart rate at 1 Hz from 6 mountain-bike riders (mean±SD age=27.2±5.0 y, stature=176.8±8.1 cm, mass=76.3±11.7 kg, VO2max=55.1±6.0 mL·kg(-1)·min1) competing in a multilap race. Lap-by-lap (interlap) pacing was analyzed using a 1-way ANOVA for mean time and mean velocity. Velocity data were averaged every 100 m and plotted against race distance and elevation to observe the presence of intralap variation. There was no significant difference in lap times (P=.99) or lap velocity (P=.65) across the 5 laps. Within each lap, a high degree of oscillation in velocity was observed, which broadly reflected changes in terrain, but high-resolution data demonstrated additional nonmonotonic variation not related to terrain. Participants adopted an even pace strategy across the 5 laps despite rapid adjustments in velocity during each lap. While topographical and technical variations of the course accounted for some of the variability in velocity, the additional rapid adjustments in velocity may be associated with dynamic regulation of self-paced exercise.

  12. 49 CFR 230.30 - Lap-joint seam boilers.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Lap-joint seam boilers. 230.30 Section 230.30..., DEPARTMENT OF TRANSPORTATION STEAM LOCOMOTIVE INSPECTION AND MAINTENANCE STANDARDS Boilers and Appurtenances Inspection and Repair § 230.30 Lap-joint seam boilers. Every boiler having lap-joint longitudinal seams...

  13. Lap belts and three-point belts.

    NARCIS (Netherlands)

    Kampen, L.T.B. van & Edelman, A.

    1975-01-01

    Results of the swov-accident investigation prove that if there are any differences in the effectiveness of lap belts and three-point belts, these are so small that they cannot form a basis for giving preference to one type over the other. Furthermore, in spite of the results of this investigation

  14. Fatigue properties of dissimilar metal laser welded lap joints

    Science.gov (United States)

    Dinsley, Christopher Paul

    This work involves laser welding austenitic and duplex stainless steel to zinc-coated mild steel, more specifically 1.2mm V1437, which is a Volvo Truck Coiporation rephosphorised mild steel. The work investigates both tensile and lap shear properties of similar and dissimilar metal laser welded butt and lap joints, with the majority of the investigation concentrating on the fatigue properties of dissimilar metal laser welded lap joints. The problems encountered when laser welding zinc-coated steel are addressed and overcome with regard to dissimilar metal lap joints with stainless steel. The result being the production of a set of guidelines for laser welding stainless steel to zinc-coated mild steel. The stages of laser welded lap joint fatigue life are defined and the factors affecting dissimilar metal laser welded lap joint fatigue properties are analysed and determined; the findings suggesting that dissimilar metal lap joint fatigue properties are primarily controlled by the local stress at the internal lap face and the early crack growth rate of the material at the internal lap face. The lap joint rotation, in turn, is controlled by sheet thickness, weld width and interfacial gap. Laser welded lap joint fatigue properties are found to be independent of base material properties, allowing dissimilar metal lap joints to be produced without fatigue failure occurring preferentially in the weaker parent material, irrespective of large base material property differences. The effects of Marangoni flow on the compositions of the laser weld beads are experimentally characterised. The results providing definite proof of the stirring mechanism within the weld pool through the use of speeds maps for chromium and nickel. Keywords: Laser welding, dissimilar metal, Zinc-coated mild steel, Austenitic stainless steel, Duplex stainless steel, Fatigue, Lap joint rotation, Automotive.

  15. New design deforming controlling system of the active stressed lap

    Science.gov (United States)

    Ying, Li; Wang, Daxing

    2008-07-01

    A 450mm diameter active stressed lap has been developed in NIAOT by 2003. We design a new lap in 2007. This paper puts on emphases on introducing the new deforming control system of the lap. Aiming at the control characteristic of the lap, a new kind of digital deforming controller is designed. The controller consists of 3 parts: computer signal disposing, motor driving and force sensor signal disposing. Intelligent numeral PID method is applied in the controller instead of traditional PID. In the end, the result of new deformation are given.

  16. Idraulica dei sistemi fognari dalla teoria alla pratica

    CERN Document Server

    Gisonni, Corrado

    2012-01-01

    La progettazione dei sistemi fognari e dei manufatti in essi presenti richiede un’attenta conoscenza delle leggi che regolano i fenomeni idraulici, con particolare riferimento alle correnti idriche a superficie libera. Partendo dalle nozioni fondamentali dell’Idraulica, il testo intende colmare alcune importanti lacune che ancora caratterizzano la letteratura italiana nel settore e che spesso sono alla base di errori progettuali, con ovvie conseguenze sulla sicurezza dei centri abitati (come testimoniato dai frequenti fenomeni di allagamento che sono stati registrati negli ultimi anni). Il libro è rivolto agli allievi dei corsi di studio nel settore dell’ingegneria Civile ed Ambientale. Particolare interesse è rivolto ai professionisti operanti nel settore della ingegneria idraulica e della pianificazione urbana, per i quali è forte l’esigenza di testi che contengano indicazioni di carattere sia teorico sia pratico, finalizzate alla progettazione di sistemi di drenaggio nei centri abitati.

  17. Il diritto alla salute dello straniero nell’ordinamento italiano

    OpenAIRE

    Monego, Davide

    2017-01-01

    The author provides a framework of the application of the provisions set up by the legislative decree no. 286/1998 on immigration, that is the most effective measure to protect migrants’ right to health. L'autore fornisce un quadro di applicazione delle disposizioni istituite dal decreto legislativo n. 286/1998 sull'immigrazione, che è la misura più efficace per proteggere il diritto dei migranti alla salute.

  18. Il diritto alla salute dei migranti nei Paesi Bassi

    OpenAIRE

    Romeo, Graziella; Palazzo, Nausica

    2017-01-01

    L’articolo affronta il tema del diritto alla salute del migrante nei Paesi Bassi. Nel far ciò si propone innanzitutto di fornire un inquadramento riguardante la condizione dello straniero dal punto di vista lato sensu costituzionale, e le politiche di assimilazione dello straniero poste in essere dal governo in anni recenti. L’articolo intende in seguito di ricostruire le peculiarità del sistema sanitario olandese e le tipologie di migranti riconosciute a livello domestico, al fine di incroc...

  19. Camminabilità e capacità urbane: valutazione e supporto alla decisione e alla pianificazione urbanistica

    Directory of Open Access Journals (Sweden)

    Ivan Blečić

    2015-06-01

    Full Text Available L’articolo propone una metodologia di valutazione della camminabilità (walkability urbana ed il rispettivo strumento software di supporto alla decisione ed alla pianificazione urbanistica. Nella parte introduttiva discutiamo la rilevanza del concetto di camminabilità per la qualità urbana ed offriamo un suo inquadramento teorico all’interno dell’approccio alle capacità (capability approach. La parte centrale è dedicata alla presentazione del modello spaziale e multicriteriale di valutazione della camminabilità. La nostra costruzione della camminabilità nel modello propone un certo ribaltamento di prospettiva rispetto ai metodi sinora proposti: anziché valutare quanto un determinato luogo è in sé camminabile, il punteggio di camminabilità calcolato riflette come e verso dove una persona può intraprendere una camminata a partire da quel luogo; in altre parole, non quanto è camminabile, ma invece qual è la camminabilità di cui il luogo è dotato. Per questo, il punteggio di camminabilità combina tre componenti: (1 il numero di destinazioni di interesse/opportunità urbane raggiungibili a piedi; (2 le loro distanze; (3 la qualità dei percorsi pedonali verso queste destinazioni. La qualità dei percorsi pedonali è valutata in base a diversi attributi rilevanti per la camminabilità, che fanno riferimento a caratteristiche proprie della strada e dell’ambiente circostante in grado di contribuire a rendere il percorso piacevole, sicuro ed attrattivo. A titolo illustrativo viene nella terza parte dell’articolo presentato un esempio di applicazione del modello alla città di Alghero.

  20. Machine Shop I. Learning Activity Packets (LAPs). Section C--Hand and Bench Work.

    Science.gov (United States)

    Oklahoma State Board of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

    This document contains two learning activity packets (LAPs) for the "hand and bench work" instructional area of a Machine Shop I course. The two LAPs cover the following topics: hand and bench work and pedestal grinder. Each LAP contains a cover sheet that describes its purpose, an introduction, and the tasks included in the LAP;…

  1. Machine Shop I. Learning Activity Packets (LAPs). Section D--Power Saws and Drilling Machines.

    Science.gov (United States)

    Oklahoma State Board of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

    This document contains two learning activity packets (LAPs) for the "power saws and drilling machines" instructional area of a Machine Shop I course. The two LAPs cover the following topics: power saws and drill press. Each LAP contains a cover sheet that describes its purpose, an introduction, and the tasks included in the LAP; learning…

  2. Machine Shop I. Learning Activity Packets (LAPs). Section A--Orientation.

    Science.gov (United States)

    Oklahoma State Board of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

    This document contains two learning activity packets (LAPs) for the "orientation and safety" instructional area of a Machine Shop I course. The two LAPs cover the following topics: orientation and general shop safety. Each LAP contains a cover sheet that describes its purpose, an introduction, and the tasks included in the LAP; learning…

  3. Riveted Lap Joints in Aircraft Fuselage Design, Analysis and Properties

    CERN Document Server

    Skorupa, Andrzej

    2012-01-01

    Fatigue of the pressurized fuselages of transport aircraft is a significant problem all builders and users of aircraft have to cope with for reasons associated with assuring a sufficient lifetime and safety, and formulating adequate inspection procedures. These aspects are all addressed in various formal protocols for creating and maintaining airworthiness, including damage tolerance considerations. In most transport aircraft, fatigue occurs in lap joints, sometimes leading to circumstances that threaten safety in critical ways. The problem of fatigue of lap joints has been considerably enlarged by the goal of extending aircraft lifetimes. Fatigue of riveted lap joints between aluminium alloy sheets, typical of the pressurized aircraft fuselage, is the major topic of the present book. The richly illustrated and well-structured chapters treat subjects such as: structural design solutions and loading conditions for fuselage skin joints; relevance of laboratory test results for simple lap joint specimens to rive...

  4. Double-Lap Shear Test For Honeycomb Core

    Science.gov (United States)

    Nettles, Alan T.; Hodge, Andrew J.

    1992-01-01

    Double-lap test measures shear strength of panel made of honeycomb core with 8-ply carbon-fiber/epoxy face sheets. Developed to overcome three principal disadvantages of prior standard single-lap shear test: specimen had to be more than 17 in. long; metal face sheets had to be used; and test introduced torque, with consequent bending and peeling of face sheets and spurious tensile or compressive loading of honeycomb.

  5. Production of biogenic amines in "Salamini italiani alla cacciatora PDO".

    Science.gov (United States)

    Coı X0308 Sson, Jean Daniel; Cerutti, Caterina; Travaglia, Fabiano; Arlorio, Marco

    2004-06-01

    Various fermented and seasoned foods such as cheese, sauerkraut, wine, beer and meat products may contain biogenic amines. The aim of this paper was to describe the presence of some biogenic amines (histamine, tyramine, tryptamine, 2-phenylethylamine) in "Salamini italiani alla cacciatora PDO", a typical fermented-ripened dry sausage widely consumed in Italy. Total level of biogenic amines in commercial samples ranged from 71 to 586 mg kg(-1). The amine recovered in higher concentrations was tyramine (372 mg kg(-1)) followed by histamine (165 mg kg(-1)). The second aim of this work was the quality control of the production in order to determine the parameters influencing the presence of biogenic amines in ripened salami. Sausages sampled for analysis during production, manipulation and ripening showed the presence of tyramine (64.4 mg kg(-1)) only after 15 days of fermentation. All investigated biogenic amines were detected in "Salamini" after 21 days of fermentation. We suggest the control of biogenic as important tool to establish the better condition of preservation of "Salamini italiani alla cacciatore PDO" during their shelf-life.

  6. Review on failure prediction techniques of composite single lap joint

    International Nuclear Information System (INIS)

    Ab Ghani, A.F.; Rivai, Ahmad

    2016-01-01

    Adhesive bonding is the most appropriate joining method in construction of composite structures. The use of reliable design and prediction technique will produce better performance of bonded joints. Several papers from recent papers and journals have been reviewed and synthesized to understand the current state of the art in this area. It is done by studying the most relevant analytical solutions for composite adherends with start of reviewing the most fundamental ones involving beam/plate theory. It is then extended to review single lap joint non linearity and failure prediction and finally on the failure prediction on composite single lap joint. The review also encompasses the finite element modelling part as tool to predict the elastic response of composite single lap joint and failure prediction numerically.

  7. Review on failure prediction techniques of composite single lap joint

    Energy Technology Data Exchange (ETDEWEB)

    Ab Ghani, A.F., E-mail: ahmadfuad@utem.edu.my; Rivai, Ahmad, E-mail: ahmadrivai@utem.edu.my [Faculty of Mechanical Engineering, Locked Bag 1200, Hang Tuah Jaya, 75450 Ayer Keroh, Melaka (Malaysia)

    2016-03-29

    Adhesive bonding is the most appropriate joining method in construction of composite structures. The use of reliable design and prediction technique will produce better performance of bonded joints. Several papers from recent papers and journals have been reviewed and synthesized to understand the current state of the art in this area. It is done by studying the most relevant analytical solutions for composite adherends with start of reviewing the most fundamental ones involving beam/plate theory. It is then extended to review single lap joint non linearity and failure prediction and finally on the failure prediction on composite single lap joint. The review also encompasses the finite element modelling part as tool to predict the elastic response of composite single lap joint and failure prediction numerically.

  8. Analysis for Behavior of Reinforcement Lap Splices in Deep Beams

    Directory of Open Access Journals (Sweden)

    Ammar Yaser Ali

    2018-03-01

    Full Text Available The present study includes an experimental and theoretical investigation of reinforced concrete deep beams containing tensile reinforcement lap splices at constant moment zone under static load. The study included two stages: in the first one, an experimental work included testing of eight simply supported RC deep beams having a total length (L = 2000 mm, overall depth (h= 600 mm and width (b = 150 mm. The tested specimens were divided into three groups to study the effect of main variables: lap length, location of splice, internal confinement (stirrups and external confinement (strengthening by CFRP laminates. The experimental results showed that the use of CFRP as external strengthening in deep beam with lap spliced gives best behavior such as increase in stiffness, decrease in deflection, delaying the cracks appearance and reducing the crack width. The reduction in deflection about (14-21 % than the unstrengthened beam and about (5-14 % than the beam with continuous bars near ultimate load. Also, it was observed that the beams with unstrengthened tensile reinforcement lap splices had three types of cracks: flexural, flexural-shear and splitting cracks while the beams with strengthened tensile reinforcement lap splices or continuous bars don’t observe splitting cracks. In the second stage, a numerical analysis of three dimensional finite element analysis was utilized to explore the behavior of the RC deep beams with tensile reinforcement lap splices, in addition to parametric study of many variables. The comparison between the experimental and theoretical results showed reasonable agreement. The average difference of the deflection at service load was less than 5%.

  9. Ability Of Mathematical Reasoning in SMK 10th Grade with LAPS- Heuristic using Performance Assessment

    OpenAIRE

    Aulia Nur Arivina; Masrukan Masrukan; Ardhi Prabowo

    2017-01-01

    The purposes of this research are: (1) Test the learning with LAPS-Heuristic model using performance assessment on 10th grade of Trigonometry material is complete, (2) to test the difference of students' mathematical reasoning ability on 10th grade of Trigonometry material between the learning model of LAPS-Heuristic using performance assessment, LAPS-Heuristic learning model with Expository learning model, (3) test the ability of mathematical reasoning with learning model of LAPS-Heuristik o...

  10. I capricci del caso Introduzione alla statistica, al calcolo delle probabilità e alla teoria degli errori

    CERN Document Server

    Piazza, Roberto

    2009-01-01

    I metodi probabilistici e statistici giocano un ruolo di primo piano sia nella scienza teorica e sperimentale che nelle applicazioni ingegneristiche, costituendo pertanto un elemento essenziale del bagaglio culturale che uno studente deve acquisire fin dai primi anni di apprendimento universitario. Questo libro, che nasce dall’esperienza didattica accumulata dall’autore nell’insegnamento dei metodi sperimentali, si propone di fornire un’introduzione al calcolo delle probabilità e alla teoria degli errori facendo uso di uno stile di presentazione volutamente informale e traendo spunto da concrete applicazioni sperimentali, spesso attraverso esempi di notevole importanza storica. Così, per esempio, argomenti quali il moto browniano, la diffusione di luce, il decadimento radioattivo, la fisiologia della visione, le statistiche quantistiche e di fotorivelazione, vengono utilizzati per delucidare concetti chiave dell’analisi statistica e probabilistica. Un'enfasi particolare è posta sull’origine e l...

  11. Auto Mechanics I. Learning Activity Packets (LAPs). Section E--Brakes.

    Science.gov (United States)

    Oklahoma State Board of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

    This document contains two learning activity packets (LAPs) that outline the study activities for the "brakes" instructional area for an Auto Mechanics I course. The two LAPs cover the following topics: brake systems and power disc brakes. Each LAP contains a cover sheet that describes its purpose, an introduction, and the tasks included…

  12. Effect of lapping slurry on critical cutting depth of spinel

    International Nuclear Information System (INIS)

    Wang, Zhan-kui; Wang, Zhuan-kui; Zhu, Yong-wei; Su, Jian-xiu

    2015-01-01

    Highlights: • Measured spinel wafers’ hardness and crack length in different slurries. • Evaluated the softened layer thickness in different slurries. • Discussed the effect of slurries on critical cutting depth of spinel. - Abstract: The critical cutting depth for lapping process is very important because it influences the mode of material removal. In this paper, a serial of microscopic indentation experiments were carried out for measuring spinel wafers’ hardness and crack length in different lapping slurries. Their critical cutting depth and fracture toughness were calculated. X-ray photoelectron spectroscopy (XPS) was also employed to study the surface chemical composition and softened layer thickness of wafers in different slurries. Experimental results indicate that the softened layers of spinel wafers are formed due to the corrosion of lapping slurries, which leads to a lower hardness and a larger fracture toughness of samples, and increases the critical cutting depth. Among them, the critical cutting depth in ethylene glycol solution is the largest and up to 21.8 nm. The increase of critical cutting depth is helpful to modify the surface quality of the work-piece being lapped via ductile removal mode instead of brittle fracture mode

  13. Baltimaade rahvusraamatukogude direktorid kirjutasid alla koostööleppele / Annika Koppel

    Index Scriptorium Estoniae

    Koppel, Annika, 1964-

    2014-01-01

    23. aprillil 2014 kirjutasid Eesti Rahvusraamatukogu peadirektor Janne Andresoo, Läti Rahvusraamatukogu direktor Andris Vilks ja Leedu Rahvusraamatukogu peadirektor Renaldas Gudauskas alla koostööd tihendavale memorandumile. Artiklile on lisatud koostöömemorandumi tekst

  14. Viljandimaal läheb kaitse alla viis kanakulli pesa / Renno Nellis ; interv. Liisi Seil

    Index Scriptorium Estoniae

    Nellis, Renno, 1982-

    2005-01-01

    Vestlus Kotkaklubi eksperdi Renno Nellisega, kes aitab organiseerida kanakulli püsielupaikade kaitse alla võtmist. Vt. samas ka artiklit: Seil, Liisi "Metsaülemad suhtuvad pesade kaitsmisse mitut moodi"

  15. Combination of TB lymphadenitis and metastatic LAP in breast cancer

    Directory of Open Access Journals (Sweden)

    Abdolhassan Talaiezadeh

    2015-06-01

    Full Text Available Tuberculosis (TB may present as pulmonary and extra-pulmonary. TB lymphadenitis is the most common presentation of extra-pulmonary TB. TB lymphadenitis should be taken into account in the differential diagnosis of different disorders such as metastatic lymphadenopathy. The reported patient was a 65-year-old lady with breast cancer and conglomerated and matted axillary lymphadenopathy who received chemotherapy. She presented with more extensive axillary LAP contrary to our expectation. Modified radical mastectomy was done and pathology analysis reported TB lymphadenitis associated with metastatic LAP. Under cover of anti-TB therapy adjuvant chemoradiation therapy was started. Accordingly, we recommend TB be ruled out in every patient who needs chemotherapy in the endemic region because chemotherapy may cause the extension of TB in the body.

  16. MSD in fuselage lap joints: Requirements for inspection intervals for typical fuselage lap joint panels with Multiple Site Damage

    Science.gov (United States)

    Wit, G. P.

    1992-07-01

    Inspection of failed aircraft structures and fractography on fatigue specimens showed that after a high number of flights, cracks can appear simultaneously in riveted lap joints. When these crack tips approach each other, a mutual interaction causes an unexpected fast crack growth and new coalescence of cracks. The term Multiple Site Damage (MSD) is used when the mutual interaction of two or more damages is noticeable. A model to predict the fatigue life of a riveted lap joint and the minimum necessary inspection interval for safe aircraft operation is presented. The program was developed to simulate the fatigue process and aircraft inspection. Input for this analysis are scatter data for initiation, the stress distribution between frames and the geometry of the structure. Methods that can be used to avoid accidents due to MSD are reviewed. A test program to support the analysis is described.

  17. Experimental Investigation into Vibration Characteristics for Damage Minimization in a Lapping Process

    Directory of Open Access Journals (Sweden)

    J. Suwatthikul

    2016-01-01

    Full Text Available Lapping machines are used in a hard disk rough lapping process where a workpiece (a wafer row bar is locked with a robot arm and rubbed on a lap plate. In this process, the lap plate’s condition and lifetime are among important concerned factors. The lifetime can be too short due to the plate being accidentally scratched by the workpiece during lapping. This problem leads to undesired consequences such as machine downtime and excessive plate material usage. This paper presents an experimental investigation into vibration characteristics of passed and failed lapping scenarios and discusses a potential solution to minimize the serious damage so-called “plate scratch” which intermittently occurs in such process. The experimental results show that, by in situ monitoring vibration and utilizing artificial intelligence, damage minimization can be possible.

  18. La Carta Geomorfologica d’Italia alla scala 1:50.000 Un fondamentale strumento per la pianificazione territoriale

    Directory of Open Access Journals (Sweden)

    Roberto Graciotti

    2007-04-01

    Full Text Available Con l’avvio del Progetto CARG (Cartografia geologica e geotematica alla fine degli anni Ottanta ad opera del Servizio Geologico Nazionale (SGN, la cartografia geomorfologica assume per il nostro Paese una particolare importanza per la sua rilevanza scientifica, soprattutto nel campo della conoscenza fisica del territorio applicata alla pianificazione territoriale.

  19. Fatigue behavior of thick composite single lap joints

    Energy Technology Data Exchange (ETDEWEB)

    Tang, J.H.; Sridhar, I.; Srikanth, N. [Nanyang Technological Univ., Singapore (Singapore)

    2012-07-01

    In consideration of bondline thickness variability, in bonded joints where thick adherend is adopted, relative thick adhesive layer (2-5 mm) is preferable. This paper aims to give some insight in fatigue strength of adhesively bonded structures involving thick adherend coupled with thick adhesive layer. Single lap joints with nominal adherend thickness of 8 mm and two different nominal thicknesses (2.5 mm and 5.5 mm) were made and tested under fatigue loading. The failure mode exhibits always a tendency for interfacial initiation, followed by interlaminar separation. Fatigue strength for higher adhesive thickness is found to be lower. (Author)

  20. Role of LAP+CD4+ T cells in the tumor microenvironment of colorectal cancer.

    Science.gov (United States)

    Zhong, Wu; Jiang, Zhi-Yuan; Zhang, Lei; Huang, Jia-Hao; Wang, Shi-Jun; Liao, Cun; Cai, Bin; Chen, Li-Sheng; Zhang, Sen; Guo, Yun; Cao, Yun-Fei; Gao, Feng

    2017-01-21

    To investigate the abundance and potential functions of LAP + CD4 + T cells in colorectal cancer (CRC). Proportions of LAP + CD4 + T cells were examined in peripheral blood and tumor/paratumor tissues of CRC patients and healthy controls using flow cytometry. Expression of phenotypic markers such as forkhead box (Fox)p3, cytotoxic T-lymphocyte-associated protein (CTLA)-4, chemokine CC receptor (CCR)4 and CCR5 was measured using flow cytometry. LAP - CD4 + and LAP + CD4 + T cells were isolated using a magnetic cell-sorting system and cell purity was analyzed by flow cytometry. Real-time quantitative polymerase chain reaction was used to measure expression of cytokines interleukin (IL)-10 and transforming growth factor (TGF)-β. The proportion of LAP + CD4 + T cells was significantly higher in peripheral blood from patients (9.44% ± 3.18%) than healthy controls (1.49% ± 1.00%, P CD4 + T cells was significantly higher in tumor tissues (11.76% ± 3.74%) compared with paratumor tissues (3.87% ± 1.64%, P CD4 + T cells and TNM stage ( P cell sorting gave an overall enrichment of LAP + CD4 + T cells (95.02% ± 2.87%), which was similar for LAP - CD4 + T cells (94.75% ± 2.76%). In contrast to LAP - CD4 + T cells, LAP + CD4 + T cells showed lower Foxp3 expression but significantly higher levels of CTLA-4, CCR4 and CCR5 ( P CD4 + T cells expressed significantly larger amounts of IL-10 and TGF-β but lower levels of IL-2, IL-4, IL-17 and interferon-γ, compared with LAP - CD4 + T cells. LAP + CD4 + T cells accumulated in the tumor microenvironment of CRC patients and were involved in immune evasion mediated by IL-10 and TGF-β.

  1. Ultrasonic guided wave inspection of Inconel 625 brazed lap joints

    Science.gov (United States)

    Comot, Pierre; Bocher, Philippe; Belanger, Pierre

    2016-04-01

    The aerospace industry has been investigating the use of brazing for structural joints, as a mean of reducing cost and weight. There therefore is a need for a rapid, robust, and cost-effective non-destructive testing method for evaluating the structural integrity of the joints. The mechanical strength of brazed joints depends mainly on the amount of brittle phases in their microstructure. Ultrasonic guided waves offer the possibility of detecting brittle phases in joints using spatio-temporal measurements. Moreover, they offer the opportunity to inspect complex shape joints. This study focused on the development of a technique based on ultrasonic guided waves for the inspection of Inconel 625 lap joints brazed with BNi-2 filler metal. A finite element model of a lap joint was used to optimize the inspection parameters and assess the feasibility of detecting the amount of brittle phases in the joint. A finite element parametric study simulating the input signal shape, the center frequency, and the excitation direction was performed. The simulations showed that the ultrasonic guided wave energy transmitted through, and reflected from, the joints was proportional to the amount of brittle phases in the joint.

  2. Edge effect modeling and experiments on active lap processing.

    Science.gov (United States)

    Liu, Haitao; Wu, Fan; Zeng, Zhige; Fan, Bin; Wan, Yongjian

    2014-05-05

    Edge effect is regarded as one of the most difficult technical issues for fabricating large primary mirrors, especially for large polishing tools. Computer controlled active lap (CCAL) uses a large size pad (e.g., 1/3 to 1/5 workpiece diameters) to grind and polish the primary mirror. Edge effect also exists in the CCAL process in our previous fabrication. In this paper the material removal rules when edge effects happen (i.e. edge tool influence functions (TIFs)) are obtained through experiments, which are carried out on a Φ1090-mm circular flat mirror with a 375-mm-diameter lap. Two methods are proposed to model the edge TIFs for CCAL. One is adopting the pressure distribution which is calculated based on the finite element analysis method. The other is building up a parametric equivalent pressure model to fit the removed material curve directly. Experimental results show that these two methods both effectively model the edge TIF of CCAL.

  3. Lap Shear Testing of Candidate Radiator Panel Adhesives

    Science.gov (United States)

    Ellis, David; Briggs, Maxwell; McGowan, Randy

    2013-01-01

    During testing of a subscale radiator section used to develop manufacturing techniques for a full-scale radiator panel, the adhesive bonds between the titanium heat pipes and the aluminum face sheets failed during installation and operation. Analysis revealed that the thermal expansion mismatch between the two metals resulted in relatively large shear stresses being developed even when operating the radiator at moderate temperatures. Lap shear testing of the adhesive used in the original joints demonstrated that the two-part epoxy adhesive fell far short of the strength required. A literature review resulted in several candidate adhesives being selected for lap shear joint testing at room temperature and 398 K, the nominal radiator operating temperature. The results showed that two-part epoxies cured at room and elevated temperatures generally did not perform well. Epoxy film adhesives cured at elevated temperatures, on the other hand, did very well with most being sufficiently strong to cause yielding in the titanium sheet used for the joints. The use of an epoxy primer generally improved the strength of the joint. Based upon these results, a new adhesive was selected for the second subscale radiator section.

  4. Mechanistic Features of Nanodiamonds in the Lapping of Magnetic Heads

    Directory of Open Access Journals (Sweden)

    Xionghua Jiang

    2014-01-01

    Full Text Available Nanodiamonds, which are the main components of slurry in the precision lapping process of magnetic heads, play an important role in surface quality. This paper studies the mechanistic features of nanodiamond embedment into a Sn plate in the lapping process. This is the first study to develop mathematical models for nanodiamond embedment. Such models can predict the optimum parameters for particle embedment. From the modeling calculations, the embedded pressure satisfies p0=3/2·W/πa2 and the indentation depth satisfies δ=k1P/HV. Calculation results reveal that the largest embedded pressure is 731.48 GPa and the critical indentation depth δ is 7 nm. Atomic force microscopy (AFM, scanning electron microscopy (SEM, and Auger electron spectroscopy (AES were used to carry out surface quality detection and analysis of the disk head. Both the formation of black spots on the surface and the removal rate have an important correlation with the size of nanodiamonds. The results demonstrate that an improved removal rate (21 nm·min−1 can be obtained with 100 nm diamonds embedded in the plate.

  5. Mechanistic features of nanodiamonds in the lapping of magnetic heads.

    Science.gov (United States)

    Jiang, Xionghua; Chen, Zhenxing; Wolfram, Joy; Yang, Zhizhou

    2014-01-01

    Nanodiamonds, which are the main components of slurry in the precision lapping process of magnetic heads, play an important role in surface quality. This paper studies the mechanistic features of nanodiamond embedment into a Sn plate in the lapping process. This is the first study to develop mathematical models for nanodiamond embedment. Such models can predict the optimum parameters for particle embedment. From the modeling calculations, the embedded pressure satisfies p 0 = (3/2) · (W/πa (2)) and the indentation depth satisfies δ = k1√P/HV. Calculation results reveal that the largest embedded pressure is 731.48 GPa and the critical indentation depth δ is 7 nm. Atomic force microscopy (AFM), scanning electron microscopy (SEM), and Auger electron spectroscopy (AES) were used to carry out surface quality detection and analysis of the disk head. Both the formation of black spots on the surface and the removal rate have an important correlation with the size of nanodiamonds. The results demonstrate that an improved removal rate (21 nm · min(-1)) can be obtained with 100 nm diamonds embedded in the plate.

  6. Ability Of Mathematical Reasoning in SMK 10th Grade with LAPS- Heuristic using Performance Assessment

    Directory of Open Access Journals (Sweden)

    Aulia Nur Arivina

    2017-11-01

    Full Text Available The purposes of this research are: (1 Test the learning with LAPS-Heuristic model using performance assessment on 10th grade of Trigonometry material is complete, (2 to test the difference of students' mathematical reasoning ability on 10th grade of Trigonometry material between the learning model of LAPS-Heuristic using performance assessment, LAPS-Heuristic learning model with Expository learning model, (3 test the ability of mathematical reasoning with learning model of LAPS-Heuristik on Trigonometry material of SMK on 10th grade using performance assessment is increase. This is a quantitative research. The population is students of 10th grade of SMK 10 Semarang academic year 2016/2017 and the subject of research is selected by clustering random sampling. The results show that (1 Learning by model LAPS-Heuristic using performance assessment on 10th grade of Trigonometry material is complete (2 there are differences in students' mathematical reasoning ability on 10th grade of Trigonometry materials between LAPS-Heuristic learning model using performance assessment, LAPS-Heuristic learning model, and Expository learning model, (3 The ability of mathematical reasoning with learning model of LAPS-Heuristic on Trigonometry material of SMK class X using performance assessment increased.

  7. Determination of face validity for the Simbionix LAP mentor virtual reality training module

    NARCIS (Netherlands)

    Ayodeji, I. D.; Schijven, M. P.; Jakimowicz, J. J.

    2006-01-01

    This study determines the expert and referent face validity of LAP Mentor, the first procedural virtual-reality (VR) trainer. After a hands-on introduction to the simulator a questionnaire was administered to 49 participants (21 expert laparoscopists and 28 novices). There was a consensus on LAP

  8. Learning Activity Package, Physics 124, (LAP) Studies 45, 47, and 48.

    Science.gov (United States)

    Holland, Bill

    Included are three Learning Activity Packages (LAP) studies for use in high school physics instruction: Time and Measurement Function; Force, Work, and Momentum; and Momentum, Work, and Energy. Each LAP contains a rationale for teaching the material included, student objectives (stated in behavioral terms), a list of resources (readings, problems,…

  9. Artificial Intelligence Mechanisms on Interactive Modified Simplex Method with Desirability Function for Optimising Surface Lapping Process

    Directory of Open Access Journals (Sweden)

    Pongchanun Luangpaiboon

    2014-01-01

    Full Text Available A study has been made to optimise the influential parameters of surface lapping process. Lapping time, lapping speed, downward pressure, and charging pressure were chosen from the preliminary studies as parameters to determine process performances in terms of material removal, lap width, and clamp force. The desirability functions of the-nominal-the-best were used to compromise multiple responses into the overall desirability function level or D response. The conventional modified simplex or Nelder-Mead simplex method and the interactive desirability function are performed to optimise online the parameter levels in order to maximise the D response. In order to determine the lapping process parameters effectively, this research then applies two powerful artificial intelligence optimisation mechanisms from harmony search and firefly algorithms. The recommended condition of (lapping time, lapping speed, downward pressure, and charging pressure at (33, 35, 6.0, and 5.0 has been verified by performing confirmation experiments. It showed that the D response level increased to 0.96. When compared with the current operating condition, there is a decrease of the material removal and lap width with the improved process performance indices of 2.01 and 1.14, respectively. Similarly, there is an increase of the clamp force with the improved process performance index of 1.58.

  10. Lapimaal alla kukkunud kopterit juhtis Eesti piirivalve piloot / Küllike Rooväli

    Index Scriptorium Estoniae

    Rooväli, Küllike, 1969-

    2005-01-01

    21. septembril Soomes Lapimaal Vuotso küla lähedal alla kukkunud väikekopterit Schweizer 300C juhtis eestlane - piirivalve lennusalga päästekopteri teine piloot Rannel Vassiljev. Lisa, kaart: Kopteriõnnetus Lapimaal

  11. L’invenzione linguistica alla scuola primaria : La didattica dell’italiano nell’esperienza montessoriana

    NARCIS (Netherlands)

    Bonazzoli, C.; Gastaldi, F.; Gobbo, F.

    2017-01-01

    In questo contributo presentiamo gli aspetti relativi alla didattica dell’italiano all’interno del laboratorio linguistico sperimentale presso la Scuola Montessori Milano. Il laboratorio prevede una serie di incontri tra le insegnanti e i ricercatori, con interventi mirati di questi ultimi in

  12. XX sajandi väärtarhitektuuri hakatakse kaitse alla võtma / Alo Lõhmus

    Index Scriptorium Estoniae

    Lõhmus, Alo

    2011-01-01

    Muinsuskaitseameti ja kultuuriministeeriumi käivitatud "Eesti XX sajandi arhitektuuri kaitsmise ja väärtustamise" projekti käigus valminud XX sajandi väärtarhitektuuri registrist, mis on eelduseks möödunud aastasaja huvitavamate ehitiste riikliku kaitse alla võtmisele

  13. uomo e galantuomo dai testi alla scena. esperienze di filologia e ...

    African Journals Online (AJOL)

    User

    Dalla scena virtuale alla scena reale, in Miscellanea eduardiana in memoria di. Franco Carmelo Greco, Napoli, ESI, 200O. Sono in corso di pubblicazione altri due miei lavori rispettivamente su L'officina di Eduardo: esperienze di filologia e semiotica (titolo della relazione da me tenuta al Convegno Maschere e Metamorfosi ...

  14. Väärtuslikud setted jääksid kavandatava gaasitoru alla / Tanel Mazur

    Index Scriptorium Estoniae

    Mazur, Tanel, 1971-

    2007-01-01

    Ilmunud ka: Narva Postiljon 1. sept. lk. 2. Akadeemik Anto Raukase sõnul ladestuvad Soome lahte Eesti majandustsooni raua- ja mangaanivarud, mis jääksid Vene-Saksa gaasijuhtme alla. Lisa: Maavara. Vt. samas: Gaasijuhtme rajaja külastus lõppes tulemusteta

  15. Campania: territorio e città di fronte alla sfida della logistica

    Directory of Open Access Journals (Sweden)

    Giuseppe Mazzeo

    2010-07-01

    Full Text Available All’interno del sistema territoriale meridionale la Regione Campania si presenta come un polo importante nel settore del trasporto e dello smistamento delle merci. Questo ruolo si è venuto rinforzando in seguito alla realizzazione di infrastrutture dedicate alla logistica, connesse ad infrastrutture di supporto. Il sistema campano presenta punte di eccellenza di livello nazionale che possono incentivare il ruolo della Regione in questo settore, ma presenta anche fattori negativi che possono rallentare il decollo del settore. Si fa riferimento alle strozzature infrastrutturali e gestionali che ne inceppano l’efficienza, ma anche alla debolezza del sistema produttivo regionale che non garantisce una massa critica locale alla logistica campana. Un terzo aspetto è la mancanza di un chiaro disegno di programmazione degli investimenti e una maggiore chiarezza dei ruoli da assegnare alle diverse iniziative, nate soprattutto sulla base di spinte localistiche non coordinate. Il paper analizza la situazione della logistica territoriale in Campania e delle sue interrelazioni territoriali individuando punti di forza e di debolezza e potenziali fattori evolutivi. Gli aspetti della logistica che vengono affrontati sono di tipo territoriale e si differenziano da quelli della logistica urbana per la quantità di merci movimentate e per la concentrazione in pochi poli strategici, in quanto queste piattaforme logistiche richiedono attrezzature specializzate e ampi spazi per la movimentazione e il deposito. L’analisi del rapporto tra territorio e logistica individua quelli che sono i principali elementi di interconnessione e, spesso, di crisi, nell’uso dello spazio fisico, in ragione degli obiettivi a volte divergenti tra il governo del territorio ed i soggetti economici. Si passa successivamente ad analizzare lo stato del movimento merci in relazione alla portualità mediterranea e lo stato del sistema logistico campano (non ancora definito in tutte le

  16. Melanin targets LC3-associated phagocytosis (LAP): A novel pathogenetic mechanism in fungal disease.

    Science.gov (United States)

    Chamilos, Georgios; Akoumianaki, Tonia; Kyrmizi, Irene; Brakhage, Axel; Beauvais, Anne; Latge, Jean-Paul

    2016-05-03

    Intracellular swelling of conidia of the major human airborne fungal pathogen Aspergillus fumigatus results in surface exposure of immunostimulatory pathogen-associated molecular patterns (PAMPs) and triggers activation of a specialized autophagy pathway called LC3-associated phagocytosis (LAP) to promote fungal killing. We have recently discovered that, apart from PAMPs exposure, cell wall melanin removal during germination of A. fumigatus is a prerequisite for activation of LAP. Importantly, melanin promotes fungal pathogenicity via targeting LAP, as a melanin-deficient A. fumigatus mutant restores its virulence upon conditional inactivation of Atg5 in hematopoietic cells of mice. Mechanistically, fungal cell wall melanin selectively excludes the CYBA/p22phox subunit of NADPH oxidase from the phagosome to inhibit LAP, without interfering with signaling regulating cytokine responses. Notably, inhibition of LAP is a general property of melanin pigments, a finding with broad physiological implications.

  17. Predicting glass-forming compositions in the Al-La and Al-La-Ni systems

    International Nuclear Information System (INIS)

    Gargarella, P.; de Oliveira, M.F.; Kiminami, C.S.; Pauly, S.; Kuehn, U.; Bolfarini, C.; Botta, W.J.; Eckert, J.

    2011-01-01

    Research highlights: → The glass-forming ability of the Al-La and Al-La-Ni systems was studied using the λ* and the λ.Δe criteria. → Both criteria predicted with just 1% at. of error the best glass-former verified so far in the Al-La system. → Four new glass-former compositions could be predicted in the Al-La-Ni system using the λ.Δe criterion. → The best glass-former reported so far in the Al-La-Ni system was found. - Abstract: In this work, a criterion considering the topological instability (λ) and the differences in the electronegativity of the constituent elements (Δe) was applied to the Al-La and Al-Ni-La systems in order to predict the best glass-forming compositions. The results were compared with literature data and with our own experimental data for the Al-La-Ni system. The alloy described in the literature as the best glass former in the Al-La system is located near the point with local maximum for the λ.Δe criterion. A good agreement was found between the predictions of the λ.Δe criterion and literature data in the Al-La-Ni system, with the region of the best glass-forming ability (GFA) and largest supercooled liquid region (ΔT x ) coinciding with the best compositional region for amorphization indicated by the λ.Δe criterion. Four new glassy compositions were found in the Al-La-Ni system, with the best predicted composition presenting the best glass-forming ability observed so far for this system. Although the λ.Δe criterion needs further refinements for completely describe the glass-forming ability in the Al-La and Al-La-Ni systems, the results demonstrated that this criterion is a good tool to predict new glass-forming compositions.

  18. C/EBPβ-LAP*/LAP Expression Is Mediated by RSK/eIF4B-Dependent Signalling and Boosted by Increased Protein Stability in Models of Monocytic Differentiation.

    Directory of Open Access Journals (Sweden)

    René Huber

    Full Text Available The transcription factor C/EBPβ plays a key role in monocytic differentiation and inflammation. Its small isoform LIP is associated with proliferation at early premonocytic developmental stages and regulated via mTOR-dependent signalling. During later stages of (premonocytic differentiation there is a considerable increase in the large C/EBPβ isoforms LAP*/LAP which inhibit proliferation thus supporting terminal differentiation. Here, we showed in different models of monocytic differentiation that this dramatic increase in the LAP*/LAP protein and LAP/LIP ratio was accompanied by an only modest/retarded mRNA increase suggesting an important role for (posttranslational mechanisms. We found that LAP*/LAP formation was induced via MEK/RSK-dependent cascades, whereas mTOR/S6K1 were not involved. Remarkably, LAP*/LAP expression was dependent on phosphorylated eIF4B, an acceleratory protein of RNA helicase eIF4A. PKR inhibition reduced the expression of eIF4B and C/EBPβ in an eIF2α-independent manner. Furthermore, under our conditions a marked stabilisation of LAP*/LAP protein occurred, accompanied by reduced chymotrypsin-like proteasome/calpain activities and increased calpastatin levels. Our study elucidates new signalling pathways inducing LAP*/LAP expression and indicates new alternative PKR functions in monocytes. The switch from mTOR- to RSK-mediated signalling to orchestrate eIF4B-dependent LAP*/LAP translation, accompanied by increased protein stability but only small mRNA changes, may be a prototypical example for the regulation of protein expression during selected processes of differentiation/proliferation.

  19. C/EBPβ-LAP*/LAP Expression Is Mediated by RSK/eIF4B-Dependent Signalling and Boosted by Increased Protein Stability in Models of Monocytic Differentiation

    Science.gov (United States)

    Christmann, Martin; Friesenhagen, Judith; Westphal, Andreas; Pietsch, Daniel; Brand, Korbinian

    2015-01-01

    The transcription factor C/EBPβ plays a key role in monocytic differentiation and inflammation. Its small isoform LIP is associated with proliferation at early premonocytic developmental stages and regulated via mTOR-dependent signalling. During later stages of (pre)monocytic differentiation there is a considerable increase in the large C/EBPβ isoforms LAP*/LAP which inhibit proliferation thus supporting terminal differentiation. Here, we showed in different models of monocytic differentiation that this dramatic increase in the LAP*/LAP protein and LAP/LIP ratio was accompanied by an only modest/retarded mRNA increase suggesting an important role for (post)translational mechanisms. We found that LAP*/LAP formation was induced via MEK/RSK-dependent cascades, whereas mTOR/S6K1 were not involved. Remarkably, LAP*/LAP expression was dependent on phosphorylated eIF4B, an acceleratory protein of RNA helicase eIF4A. PKR inhibition reduced the expression of eIF4B and C/EBPβ in an eIF2α-independent manner. Furthermore, under our conditions a marked stabilisation of LAP*/LAP protein occurred, accompanied by reduced chymotrypsin-like proteasome/calpain activities and increased calpastatin levels. Our study elucidates new signalling pathways inducing LAP*/LAP expression and indicates new alternative PKR functions in monocytes. The switch from mTOR- to RSK-mediated signalling to orchestrate eIF4B-dependent LAP*/LAP translation, accompanied by increased protein stability but only small mRNA changes, may be a prototypical example for the regulation of protein expression during selected processes of differentiation/proliferation. PMID:26646662

  20. Laps olla muretuna veel / George Gordon Byron ; tlk. Minni Nurme

    Index Scriptorium Estoniae

    Byron, George Gordon

    2006-01-01

    Sisu: Laps olla muretuna veel ; Lachin y Gair ; Romantikale ; Värsid, kirjutatud pärnapuule Harrowþ kalmistu mäel ; Augustale : "Kui süngeks läks mu silmapiir..." ; Augustale : "Kuigi öö ju on varjand mu päeva..." ; Maryle ; Ela hästi! ; Nutvale neitsile ; Kirjutus albumisse ; Hüvastijätt ; Stantsid muusikast ; Muusikale ; Ta oma kauniduses käib ; Mu hing on morn ; Su elu lõppes ; Sa nutsid - pisarpärle täis... ; Unetuma päike ; Kuulsa Kreeka sõjalaulu järele ; Värsid ; Ludiidide laul ; Epigramme ; Pimedus ; Chilloni vang ; Prometheus ; Childe Haroldi palveränd ; Parisina ; Korsaar ; Byroni viimased read. Eluloolisi andmeid autori kohta lk. 327

  1. Lap-joint testing of precoated steel materials

    Directory of Open Access Journals (Sweden)

    Chico, B.

    2003-12-01

    Full Text Available In industry, particularly in the building construction, lap-joint technology for precoated steel sheet materials has undergone rapid development. However, standars for lap-joint testing are lacking. This work analyses the behaviour of four precoated steel materials commonly used in the building industry: 55 % Al-Zn and hot dip galvanized, painted and unpainted. Two-year atmospheric exposure tests have been carried out in Madrid and Avilés (Spain, complemented by accelerated weathering tests in climatic cabinets. The latter have consisted of two salt fog/humidity/drying cycles: VDA cycle 621-415 and the "CENIM cycle", which has been designed to adequately simulate the behaviour of materials in this type of joints.

    En la industria en general y, particularmente, en la industria de la construcción, las tecnologías sobre uniones solapadas han experimentado un rápido desarrollo. Sin embargo, no son abundantes los ensayos para este tipo de uniones. Este trabajo analiza el comportamiento de cuatro materiales de acero pre-recubierto comúnmente usados en la industria de la construcción: 55 % Al-Zn y galvanizado por inmersión en caliente, con recubrimiento orgánico y sin él. Se han realizado ensayos de exposición natural durante dos años en las atmósferas de Madrid y Avilés (España, complementados con ensayos de envejecimiento acelerado en cámaras climáticas. En estos últimos se han ensayado dos ciclos de proyección niebla salina/humedad/secado: ciclo VDA 621-415 y un ciclo desarrollado en el CENIM diseñado.

  2. Menetlejate küsitlemistehnikad : alla 14-aastaste laste ülekuulamisprotokollide analüüs / Kristjan Kask

    Index Scriptorium Estoniae

    Kask, Kristjan, 1980-

    2010-01-01

    Alla 14-aastaste laste kohtueelse ülekuulamise videosalvestiste analüüsist. Ülevaade põhineb Justiitsministeeriumi poolt 2009. aastal läbi viidud uurimisprojektil "Alaealiste ülekuulamine kriminaalmenetluses". Tabelid

  3. Sicurezza nazionale e diritto di libertà religiosa. Alcune considerazioni alla luce della recente esperienza statunitense

    Directory of Open Access Journals (Sweden)

    Pasquale Annicchino

    2017-02-01

    SOMMARIO: 1. Introduzione – 2. La sorveglianza di massa alla luce del caso “Snowden” – 3. Il caso del New York Police Department – 4. Primo emendamento costituzionale e nuove tecnologie – 5. Conclusioni.

  4. Global-Local Finite Element Analysis of Bonded Single-Lap Joints

    Science.gov (United States)

    Kilic, Bahattin; Madenci, Erdogan; Ambur, Damodar R.

    2004-01-01

    Adhesively bonded lap joints involve dissimilar material junctions and sharp changes in geometry, possibly leading to premature failure. Although the finite element method is well suited to model the bonded lap joints, traditional finite elements are incapable of correctly resolving the stress state at junctions of dissimilar materials because of the unbounded nature of the stresses. In order to facilitate the use of bonded lap joints in future structures, this study presents a finite element technique utilizing a global (special) element coupled with traditional elements. The global element includes the singular behavior at the junction of dissimilar materials with or without traction-free surfaces.

  5. Il Centro Nascita Montessori. Dal neonato in famiglia al bambino e alla famiglia nel servizio educativo

    Directory of Open Access Journals (Sweden)

    Laura Franceschini

    2010-02-01

    Full Text Available Intervento al Workshop Internazionale “Infanzie e Famiglie in Europa”, del 16 ottobre 2009, presso la Facoltà di Scienze della Formazione, Via Filippo Re, 6 Bologna (Aula Magna. L’intervento illustra i valori fondativi del Centro Nascita Montessori dalle sue origini ai giorni nostri attraverso un percorso che si è allargato nel tempo: dalla focalizzata attenzione e cura al neonato in famiglia o nel brefotrofio fino agli anni ’60 alla cura della crescita del bambino nei servizi educativi e alla cura della relazione con le famiglie dagli anni ‘70 in poi. Tale espansione del campo di interesse e d’indagine operativa ha arricchito il patrimonio di competenze e di conoscenze del C.N.M..

  6. «... Cercare l'esperienza alla sua fonte». Il dono della verità

    Directory of Open Access Journals (Sweden)

    Vincenzo Vitiello

    2011-11-01

    Full Text Available Un cammino nel territorio della conoscenza, da Wittgenstein a Kant, da Aristotele a Platone, con finale apertura all’etica dell’«accanto», dell’io tu a se medesimo e di se medesimo, ovvero: alla filosofia come testimonianza, alla verità come dono d’altri. «...Look for the experience at its source». The gift of truth A path into the territory of knowledge, from Wittgenstein to Kant, from Aristotle to Plato, with a final opening to the ethics of 'beside', of the I (that is «You» towards Himself and of Himself; that is, to philosophy as witness, to truth as others' gift.

  7. Introduzione alla Teoria della elasticità Meccanica dei solidi continui in regime lineare elastico

    CERN Document Server

    Colombo, Luciano

    2007-01-01

    La meccanica dei solidi rappresenta un corpus di conoscenze di formidabile robustezza concettuale, di raffinata eleganza matematico-formale e di grandissima utilita’ applicativa. Come tale ha una valenza formativa molto forte in diversi campi delle scienze naturali (fisica della materia, scienza dei materiali), ingegneristiche (scienza delle costruzioni, ingegneria strutturale e meccanica) e matematiche (matematica applicata). La teoria della elasticita’costituisce inoltre uno dei punti-cardine su cui si articola il moderno paradigma di ricerca detto "modellazione multi-scala dei materiali", secondo il quale le proprieta’ di un materiale sono descritte tramite la concorrenza di metodi teorici affatto diversi: mentre alla nanoscala opera la meccanica quantistica, alla micro- e meso-scala opera il continuo. La conoscenza del continuo elastico abilita lo Studente di Fisica, di Scienza dei Materiali, di Matematica o l’Allievo Ingegnere a confrontarsi con questo moderno e affascinate strumento di ricerca s...

  8. Grey Water Reuse for Agricultural Purposes in the Jordan Valley: Household Survey Results in Deir Alla

    OpenAIRE

    Al-Mashaqbeh, Othman A.; Ghrair, Ayoup M.; Megdal, Sharon B.

    2012-01-01

    Installation of decentralized grey water treatment systems in small rural communities contributes to a more sustainable water supply. In order to gauge community attitudes about collection and use of grey water, a door-to-door survey in the farming community of Deir Alla, Jordan was conducted by Royal Scientific Society interviewers. Outcomes of a detailed survey, designed specifically for this project, offer insights on people’s views on general water and wastewater issues, as well as their ...

  9. Laps ja pere vajavad enam tähelepanu / Anne Tiko

    Index Scriptorium Estoniae

    Tiko, Anne, 1949-

    2001-01-01

    Lääne-Viru Maavalitsuse, Lastekaitse Liidu ja TPÜ sotsiaaltöö osakonna korraldatud kuuenda vabariikliku lastekaitsekonverentsi "Laps ja pere tänases Eestis" pöördumine haridus- ja sotsiaalministeeriumi poole

  10. PROTECTIVE TREATMENTS FOR LAPPED PORCELAIN STONEWARE TILES AND EVALUATION OF THEIR CLEANABILITY

    Directory of Open Access Journals (Sweden)

    Elisa Rambaldi

    2017-09-01

    Full Text Available Since the arrival of lapped porcelain stoneware tiles on the market, several studies have been focused on the improvement of the technical characteristics of the surfaces of these products. Surface lapping induces aesthetical improvements, but can at the same time deteriorate the performance of porcelain stoneware tiles. To overcome this problem, it is possible to protect the lapped surface with commercial waterproofing materials. In this work, lapped commercial porcelain stoneware tiles with protective stain proofing agents (FILA PD15 and FILA 1239 Plus were evaluated. The stain resistance and chemical resistance results were correlated to the morphological surface characteristics of the products with and without protection. A systematic study of the surface porosity of the tiles was carried out. Results showed that unprotected surface pores tend to fill with dirt that is hardly removable by ordinary maintenance. If the pores are protected, the dirt from foot traffic is deposited only superficially and can be removed.

  11. On the water lapping of felines and the water running of lizards: A unifying physical perspective

    OpenAIRE

    Aristoff, Jeffrey M; Stocker, Roman; Reis, Pedro M; Jung, Sunghwan

    2011-01-01

    We consider two biological phenomena taking place at the air-water interface: the water lapping of felines and the water running of lizards. Although seemingly disparate motions, we show that they are intimately linked by their underlying hydrodynamics and belong to a broader class of processes called Froude mechanisms. We describe how both felines and lizards exploit inertia to defeat gravity, and discuss water lapping and water running in the broader context of water exit and water entry, r...

  12. Fatigue strength of a single lap joint SPR-bonded

    International Nuclear Information System (INIS)

    Di Franco, G.; Fratini, L.; Pasta, A.

    2011-01-01

    In the last years, hybrid joints, meaning with this the joints which consist in combining a traditional mechanical joint to a layer of adhesive, are gradually attracting the attention of various sectors of the construction of vehicles and transportation industries, for their better performance compared to just mechanical joints (self-piercing riveting SPR, riveting, and so on) or just to bonded joints.The paper investigates the fatigue behavior of a single lap joint self-piercing riveted (SPR) and bonded throughout fatigue tests. The considered geometric configuration allowed the use of two rivets placed longitudinally; an epoxy resin was used as adhesive. In the first part of the work static characterization of the joints was carried out through tensile tests. Then fatigue tests were made with the application of different levels of load. The fatigue curves were also obtained at the varying the distance between the two rivets in order to better assess the joint strength for a given length of overlap.

  13. Molten pool characterization of laser lap welded copper and aluminum

    Science.gov (United States)

    Xue, Zhiqing; Hu, Shengsun; Zuo, Di; Cai, Wayne; Lee, Dongkyun; Elijah, Kannatey-Asibu, Jr.

    2013-12-01

    A 3D finite volume simulation model for laser welding of a Cu-Al lap joint was developed using ANSYS FLUENT to predict the weld pool temperature distribution, velocity field, geometry, alloying element distribution and transition layer thickness—all key attributes and performance characteristics for a laser-welded joint. Melting and solidification of the weld pool was simulated with an enthalpy-porosity formulation. Laser welding experiments and metallographic examination by SEM and EDX were performed to investigate the weld pool features and validate the simulated results. A bowl-shaped temperature field and molten pool, and a unique maximum fusion zone width were observed near the Cu-Al interface. Both the numerical simulation and experimental results indicate an arch-shaped intermediate layer of Cu and Al, and a gradual transition of Cu concentration from the aluminum plate to the copper plate with high composition gradient. For the conditions used, welding with Cu on top was found to result in a better weld joint.

  14. Molten pool characterization of laser lap welded copper and aluminum

    International Nuclear Information System (INIS)

    Xue, Zhiqing; Hu, Shengsun; Zuo, Di; Cai, Wayne; Lee, Dongkyun; Elijah, Kannatey-Asibu Jr

    2013-01-01

    A 3D finite volume simulation model for laser welding of a Cu–Al lap joint was developed using ANSYS FLUENT to predict the weld pool temperature distribution, velocity field, geometry, alloying element distribution and transition layer thickness—all key attributes and performance characteristics for a laser-welded joint. Melting and solidification of the weld pool was simulated with an enthalpy-porosity formulation. Laser welding experiments and metallographic examination by SEM and EDX were performed to investigate the weld pool features and validate the simulated results. A bowl-shaped temperature field and molten pool, and a unique maximum fusion zone width were observed near the Cu–Al interface. Both the numerical simulation and experimental results indicate an arch-shaped intermediate layer of Cu and Al, and a gradual transition of Cu concentration from the aluminum plate to the copper plate with high composition gradient. For the conditions used, welding with Cu on top was found to result in a better weld joint. (paper)

  15. I giovani e la democrazia in Portogallo: alla ricerca di un nuovo paradigma?

    Directory of Open Access Journals (Sweden)

    Marco Lisi

    2012-08-01

    Full Text Available In Portogallo, al pari degli altri paesi europei, la disaffezione e l’apatia politica sono assai sviluppate, soprattutto tra le giovani generazioni. L’articolo utilizza i dati dell’indagine sulla qualità della democrazia per analizzare la relazione tra giovani e politica in Portogallo. La partecipazione non convenzionale e la mobilitazione cognitiva si stanno affermando, ma in maniera minore rispetto ad altri paesi, sebbene anche in Portogallo le mobilitazioni di protesta siano aumentate a seguito della crisi economica. La peculiarità del caso portoghese può essere spiegata come facendo riferimento alla breve storia democratica e alle caratteristiche del sistema politico.

  16. Il volgare e il principe. Politica culturale e questione della lingua alla corte di Cosimo

    Directory of Open Access Journals (Sweden)

    Margherita Quaglino

    2015-09-01

    Full Text Available Il principato di Cosimo I rappresenta un periodo di snodo fondamentale per la questione della lingua italiana. Il contributo ripercorre la bibliografia degli ultimi vent’anni con l’intento di definirne le principali traiettorie e individuarne l’originalità e le prospettive future rispetto agli studi precedenti. Sono esaminati in particolare gli studi relativi all’opera di Benedetto Varchi e Vincenzio Borghini; ai volgarizzamenti di Giovan Battista Gelli e Cosimo Bartoli; alla redazione e all’edizione delle Vite di Vasari e al rapporto tra letterati e artisti nella celebrazione del potere.

  17. Approcci innovativi alla mobilità urbana: il caso di Istanbul

    Directory of Open Access Journals (Sweden)

    Cecilia Scoppetta

    2010-02-01

    Full Text Available  L'attuale assetto dell'area metropolitana di Istanbul evidenzia con chiarezza il rapporto tra sistema della mobilità urbana ed espansione incontrollata del costruito. Gli strumenti di pianificazione utilizzati nel passato si sono rivelati inefficaci ed hanno prodotto una città in larga parte illegale che oggi appare ingovernabile. Tuttavia anche i nuovi strumenti del piano strategico e del progetto urbano sembrano mostrare i propri limiti. Una maggiore integrazione tra politiche urbane ancora troppo settoriali può contribuire alla definizione di approcci realmente innovativi.

  18. La crescita di Gesù nello Spirito Santo alla luce di Lc 4, 1. 14

    OpenAIRE

    Piotr Florencjan Szymański

    2006-01-01

    L’autore analizza i due versetti di Lc (4, 1. 14) in cui appare in modo evidente il legame fra Gesù e lo Spirito Santo nel contesto della tentazione del Signore da parte del diavolo. L’indagine di Lc 4, 1 mostra che Gesù, come in Mt e Mc, fu condotto nel deserto dallo Spirito che Egli ha ricevuto al battesimo. Grazie alla forza dello Spirito, Gesù è capace di affrontare il diavolo nella lotta iniziale decisiva e poi compiere fedelmente la sua missione. Realizzandola il Sig...

  19. Un sistema di supporto alla decisione per facilitare nuove azioni di finanziamento in ambito pubblico

    Directory of Open Access Journals (Sweden)

    Maria Franca Norese

    2014-12-01

    Full Text Available Un approfondimento analitico sulle modalità di finanziamento che hanno interessato la Regione Piemonte, sviluppato con il contributo di chi vi ha operato direttamente, ha permesso di acquisire, codificare e organizzare importanti elementi di conoscenza e di proporne l’uso per accrescere la cultura valutativa in Regione. Un accresciuto interesse a rendere più efficienti le azioni di finanziamento pubblico ha spinto ad utilizzare i risultati dell’analisi effettuata in un modello multicriteri di valutazione e in un sistema di supporto alla decisione rivolto a facilitare i nuovi processi di finanziamento e rendere operative attività di monitoraggio in un contesto di apprendimento organizzativo.

  20. Impact damage response of natural stitched single lap-joint in composite structures

    International Nuclear Information System (INIS)

    Ghasemnejad, H.; Argentiero, Y.; Tez, T.A.; Barrington, P.E.

    2013-01-01

    Highlights: • To study the impact resistance of single lap-joints in composite structures. • To improve the impact resistance of stitched single lap joints using natural Flax yarn. • To investigate the effect of stitching on the damage process of composite materials. • To develop FE techniques to model the impact process of composite structures using LSDYNA. - Abstract: In this paper the damage behaviour of natural stitched composite single lap-joints are investigated under low velocity impact loading conditions. For this study, the laminated hybrid composite beams were pinned using Flax yarns before curing process. The Charpy impact test was chosen to study the energy absorbing capability of single lap composite joints. Composite beams were fabricated from combination of glass/epoxy and carbon/epoxy composites. It was shown that composite beams which are stitched through the thickness are able to absorb more energy in comparison with adhesive bonded composite joints in the hybrid composite beams. The Charpy impact test of stitched composite single lap joint was also simulated by finite element analysis using software LS-DYNA and the results verified with relevant experimental data

  1. Small molecules targeting LapB protein prevent Listeria attachment to catfish muscle.

    Directory of Open Access Journals (Sweden)

    Ali Akgul

    Full Text Available Listeria monocytogenes is a Gram-positive foodborne pathogen and the causative agent of listeriosis. L. monocytogenes lapB gene encodes a cell wall surface anchor protein, and mutation of this gene causes Listeria attenuation in mice. In this work, the potential role of Listeria LapB protein in catfish fillet attachment was investigated. To achieve this, boron-based small molecules designed to interfere with the active site of the L. monocytogenes LapB protein were developed, and their ability to prevent L. monocytogenes attachment to fish fillet was tested. Results indicated that seven out of nine different small molecules were effective in reducing the Listeria attachment to catfish fillets. Of these, three small molecules (SM3, SM5, and SM7 were highly effective in blocking Listeria attachment to catfish fillets. This study suggests an alternative strategy for reduction of L. monocytogenes contamination in fresh and frozen fish products.

  2. Numerical modelling in friction lap joining of aluminium alloy and carbon-fiber-reinforced-plastic sheets

    Science.gov (United States)

    Das, A.; Bang, H. S.; Bang, H. S.

    2018-05-01

    Multi-material combinations of aluminium alloy and carbon-fiber-reinforced-plastics (CFRP) have gained attention in automotive and aerospace industries to enhance fuel efficiency and strength-to-weight ratio of components. Various limitations of laser beam welding, adhesive bonding and mechanical fasteners make these processes inefficient to join metal and CFRP sheets. Friction lap joining is an alternative choice for the same. Comprehensive studies in friction lap joining of aluminium to CFRP sheets are essential and scare in the literature. The present work reports a combined theoretical and experimental study in joining of AA5052 and CFRP sheets using friction lap joining process. A three-dimensional finite element based heat transfer model is developed to compute the temperature fields and thermal cycles. The computed results are validated extensively with the corresponding experimentally measured results.

  3. The Help-line "Invito alla Vita": a new project for suicide prevention in Trentino region.

    Science.gov (United States)

    Di Napoli, Wilma; Andreatta, Olaf

    2014-11-01

    "Invito alla Vita" is a community-based suicide prevention project that officially started in Trentino in late 2008. The project was promoted by the local Health Services, trying from the beginning to involve other community subjects, and has been working over five years and a half in different directions, particularly promoting a phone help-line. The aims of the Invito alla Vita (IaV) Help Line have been clear from the beginning: decrease the sense of loneliness, offer encouragement and support, promote engagement with health services, reduce stigma and prejudice. Contrary to popular misconceptions, talking with people about suicide will not increase suicide risk, neither will it induce patients to commit suicide.The volunteers involved in the IaV help-line offer people empathic listening without judgment and easy tips, to reduce loneliness, sadness and supply reassurance that other people care. In this study we tried to deepen our knowledges about the volunteers' motivations and necessities to use them for creating a better system of support: we realized indeed that continuous training and supervision, along with official awards given by community institutions, are basic factors to sustain the volunteers' motives to cooperate with the help line.

  4. Fast downscaled inverses for images compressed with M-channel lapped transforms.

    Science.gov (United States)

    de Queiroz, R L; Eschbach, R

    1997-01-01

    Compressed images may be decompressed and displayed or printed using different devices at different resolutions. Full decompression and rescaling in space domain is a very expensive method. We studied downscaled inverses where the image is decompressed partially, and a reduced inverse transform is used to recover the image. In this fashion, fewer transform coefficients are used and the synthesis process is simplified. We studied the design of fast inverses, for a given forward transform. General solutions are presented for M-channel finite impulse response (FIR) filterbanks, of which block and lapped transforms are a subset. Designs of faster inverses are presented for popular block and lapped transforms.

  5. Analysis of Balanced Double Lap Joints with a Bi-Linear Softening Adhesive

    DEFF Research Database (Denmark)

    Hansen, Christian Skodborg; Stang, Henrik; Schmidt, Jacob Wittrup

    2010-01-01

    of cracked concrete disks strengthened with adhesive bonded fiber reinforced polymers (FRP), or in any other structure comparable to a double lap joint with a softening interface. The present constitutive model can be changed to fit any model with the same shape of constitutive relationship, see Figure 1.......The response of a bonded symmetric balanced double lap joint under tensile loading with a bilinear softening adhesive is described with a closed form solution. Since bonded joints in concrete structures undergo softening, a versatile model to describe the response for a wide range of constitutive...

  6. Face validation of the Simbionix LAP Mentor virtual reality training module and its applicability in the surgical curriculum

    NARCIS (Netherlands)

    Ayodeji, I. D.; Schijven, M.; Jakimowicz, J.; Greve, J. W.

    2007-01-01

    BACKGROUND: The goal of our study was to determine expert and referent face validity of the LAP Mentor, the first procedural virtual reality (VR) laparoscopy trainer. METHODS: In The Netherlands 49 surgeons and surgical trainees were given a hands-on introduction to the Simbionix LAP Mentor training

  7. LAP TGF-Beta Subset of CD4+CD25+CD127− Treg Cells is Increased and Overexpresses LAP TGF-Beta in Lung Adenocarcinoma Patients

    Science.gov (United States)

    Islas-Vazquez, Lorenzo; Aguilar-Cazares, Dolores; Meneses-Flores, Manuel; Galicia-Velasco, Miriam; Romero-Garcia, Susana; Camacho-Mendoza, Catalina; Lopez-Gonzalez, Jose Sullivan

    2015-01-01

    Lung cancer is the leading cause of cancer death worldwide. Adenocarcinoma, the most commonly diagnosed histologic type of lung cancer, is associated with smoking. Cigarette smoke promotes inflammation on the airways, which might be mediated by Th17 cells. This inflammatory environment may contribute to tumor development. In contrast, some reports indicate that tumors may induce immunosuppressive Treg cells to dampen immune reactivity, supporting tumor growth and progression. Thus, we aimed to analyze whether chronic inflammation or immunosuppression predominates at the systemic level in lung adenocarcinoma patients, and several cytokines and Th17 and Treg cells were studied. Higher proportions of IL-17-producing CD4+ T-cells were found in smoking control subjects and in lung adenocarcinoma patients compared to nonsmoking control subjects. In addition, lung adenocarcinoma patients increased both plasma concentrations of IL-2, IL-4, IL-6, and IL-10, and proportions of Latency Associated Peptide (LAP) TGF-β subset of CD4+CD25+CD127− Treg cells, which overexpressed LAP TGF-β. This knowledge may lead to the development of immunotherapies that could inhibit the suppressor activity mediated by the LAP TGF-β subset of CD4+CD25+CD127− Treg cells to promote reactivity of immune cells against lung adenocarcinoma cells. PMID:26582240

  8. LAP TGF-Beta Subset of CD4+CD25+CD127− Treg Cells is Increased and Overexpresses LAP TGF-Beta in Lung Adenocarcinoma Patients

    Directory of Open Access Journals (Sweden)

    Lorenzo Islas-Vazquez

    2015-01-01

    Full Text Available Lung cancer is the leading cause of cancer death worldwide. Adenocarcinoma, the most commonly diagnosed histologic type of lung cancer, is associated with smoking. Cigarette smoke promotes inflammation on the airways, which might be mediated by Th17 cells. This inflammatory environment may contribute to tumor development. In contrast, some reports indicate that tumors may induce immunosuppressive Treg cells to dampen immune reactivity, supporting tumor growth and progression. Thus, we aimed to analyze whether chronic inflammation or immunosuppression predominates at the systemic level in lung adenocarcinoma patients, and several cytokines and Th17 and Treg cells were studied. Higher proportions of IL-17-producing CD4+ T-cells were found in smoking control subjects and in lung adenocarcinoma patients compared to nonsmoking control subjects. In addition, lung adenocarcinoma patients increased both plasma concentrations of IL-2, IL-4, IL-6, and IL-10, and proportions of Latency Associated Peptide (LAP TGF-β subset of CD4+CD25+CD127− Treg cells, which overexpressed LAP TGF-β. This knowledge may lead to the development of immunotherapies that could inhibit the suppressor activity mediated by the LAP TGF-β subset of CD4+CD25+CD127− Treg cells to promote reactivity of immune cells against lung adenocarcinoma cells.

  9. Pono tibi istam: “Tu curris”.Uno sguardo alla teoria medievale delle obbligazioni

    Directory of Open Access Journals (Sweden)

    Riccardo Strobino

    2008-12-01

    Full Text Available La teoria delle obbligazioni rappresenta un significativo esempio di come un insieme di tecniche logiche possa essere applicato, in maniera feconda, a contesti disputazionali in cui la dimensione dialogica e l’interazione tra soggetti coinvolti in un confronto dialettico hanno un ruolo di primo piano. L’attenzione che numerosi studiosi hanno manifestato nei confronti di questa parte della logica modernorum negli ultimi quarat’anni testimonia la profondità e la difficoltà dei problemi teorici che stanno alla base della teoria. Molte interpretazioni sono state avanzate circa le motivazioni che spingono i logici medievali a scrivere trattati in cui il portato delle loro dottrine logiche – come, ad esempio, la teoria delle consequentiae - viene declinato ed elaboratamente applicato al gioco dialettico tra due disputanti. La gamma di tali letture comprende differenti ipotesi: la teoria delle obbligazioni potrebbe fornire un nucleo di regole per l’impostazione di un metodo assiomatico rudimentale così come rappresentare un tentativo di elaborare esercizi volti a valutare le capacità logiche degli studenti o, ancora, un gioco teorico, svincolato dall’effettiva applicazione a contesti concreti, la cui finalità sarebbe il mantenimento della coerenza logica. E’ stata sostenuta da più interpreti la funzione pedagogica svolta dalla teoria, al di là del fatto che si tratti o meno di un metodo per la conduzione effettiva di dispute reali. Un’altra linea interpretativa collega la teoria delle obbligazioni al contesto della letteratura dei sophismata e degli insolubilia, dal cui repertorio, in effetti, sono spesso tratti molti degli esempi che si incontrano nella lettura dei trattati de obligationibus. In questo senso, la teoria offrirebbe regole e schemi di risposta che un interlocutore deve utilizzare per risolvere o rispondere a enunciati problematici o paradossali. Non si può escludere, inoltre, che nella teoria si realizzi un

  10. iLAP: a workflow-driven software for experimental protocol development, data acquisition and analysis

    Directory of Open Access Journals (Sweden)

    McNally James

    2009-01-01

    Full Text Available Abstract Background In recent years, the genome biology community has expended considerable effort to confront the challenges of managing heterogeneous data in a structured and organized way and developed laboratory information management systems (LIMS for both raw and processed data. On the other hand, electronic notebooks were developed to record and manage scientific data, and facilitate data-sharing. Software which enables both, management of large datasets and digital recording of laboratory procedures would serve a real need in laboratories using medium and high-throughput techniques. Results We have developed iLAP (Laboratory data management, Analysis, and Protocol development, a workflow-driven information management system specifically designed to create and manage experimental protocols, and to analyze and share laboratory data. The system combines experimental protocol development, wizard-based data acquisition, and high-throughput data analysis into a single, integrated system. We demonstrate the power and the flexibility of the platform using a microscopy case study based on a combinatorial multiple fluorescence in situ hybridization (m-FISH protocol and 3D-image reconstruction. iLAP is freely available under the open source license AGPL from http://genome.tugraz.at/iLAP/. Conclusion iLAP is a flexible and versatile information management system, which has the potential to close the gap between electronic notebooks and LIMS and can therefore be of great value for a broad scientific community.

  11. Learning Activity Package, Algebra 93-94, LAPs 12-22.

    Science.gov (United States)

    Evans, Diane

    A set of 11 teacher-prepared Learning Activity Packages (LAPs) in beginning algebra, these units cover sets, properties of operations, operations over real numbers, open expressions, solution sets of equations and inequalities, equations and inequalities with two variables, solution sets of equations with two variables, exponents, factoring and…

  12. Learning Activity Package, Physical Science. LAP Numbers 8, 9, 10, and 11.

    Science.gov (United States)

    Williams, G. J.

    These four units of the Learning Activity Packages (LAPs) for individualized instruction in physical science cover nuclear reactions, alpha and beta particles, atomic radiation, medical use of nuclear energy, fission, fusion, simple machines, Newton's laws of motion, electricity, currents, electromagnetism, Oersted's experiment, sound, light,…

  13. Analysis of an adhesively bonded single lap joint subjected to eccentric loading

    DEFF Research Database (Denmark)

    Anyfantis, Konstantinos; Tsouvalis, N. G.

    2013-01-01

    is benchmarking of computational tools. The test is based on a Single Lap Joint subjected to Eccentric Loading (SLJ-EL). The basic concept that lies behind this configuration is that the applied in-plane tensile load leads the adhesive layer to develop normal stresses, in-plane and out-of-plane shear stresses...

  14. Learning Activity Package, Physical Science. LAP Numbers 1, 2, 3, and 4.

    Science.gov (United States)

    Williams, G. J.

    These four units of the Learning Activity Packages (LAPs) for individualized instruction in physical science cover measuring techniques, operations of instruments, metric system heat, matter, energy, elements, atomic numbers, isotopes, molecules, mixtures, compounds, physical and chemical properties, liquids, solids, and gases. Each unit contains…

  15. Improving Critical Thinking Skills Using Learning Model Logan Avenue Problem Solving (LAPS)-Heuristic

    Science.gov (United States)

    Anggrianto, Desi; Churiyah, Madziatul; Arief, Mohammad

    2016-01-01

    This research was conducted in order to know the effect of Logan Avenue Problem Solving (LAPS)-Heuristic learning model towards critical thinking skills of students of class X Office Administration (APK) in SMK Negeri 1 Ngawi, East Java, Indonesia on material curve and equilibrium of demand and supply, subject Introduction to Economics and…

  16. The Fundamental Reasons Why Laptop Computers should not be Used on Your Lap

    Directory of Open Access Journals (Sweden)

    Mortazavi S. A. R.

    2016-12-01

    Full Text Available As a tendency to use new technologies, gadgets such as laptop computers are becoming more popular among students, teachers, businessmen and office workers. Today laptops are a great tool for education and learning, work and personal multimedia. Millions of men, especially those in the reproductive age, are frequently using their laptop computers on the lap (thigh. Over the past several years, our lab has focused on the health effects of exposure to different sources of electromagnetic fields such as cellular phones, mobile base stations, mobile phone jammers, laptop computers, radars, dentistry cavitrons and Magnetic Resonance Imaging (MRI. Our own studies as well as the studies performed by other researchers indicate that using laptop computers on the lap adversely affects the male reproductive health. When it is placed on the lap, not only the heat from a laptop computer can warm men’s scrotums, the electromagnetic fields generated by laptop’s internal electronic circuits as well as the Wi-Fi Radiofrequency radiation hazards (in a Wi-Fi connected laptop may decrease sperm quality. Furthermore, due to poor working posture, laptops should not be used on the lap for long hours.

  17. Sulle ipotesi che stanno alla base della geometria e altri scritti scientifici e filosofici

    CERN Document Server

    Riemann, Bernhard

    1994-01-01

    Il volume raccoglie, oltre al testo della lezione del 1854 che dà il titolo all'opera, alcuni scritti di carattere scientifico e filosofico di Riemann. A saggi di argomento scientifico si affiancano scritti di argomento più direttamente metodologico. La concezione della scienza che ci viene offerta da questi scritti è assai significativa del personaggio e della sua epoca. Per Riemann la matematica non è un mero strumento esteriore da applicare, appunto dall'esterno, ai fenomeni. Al contrario, essa consente di spingersi con il rigore necessario oltre alla superficie dei fenomeni e di penetrare sempre più a fondo nella realtà, nell'ottica di un sistema unitario e quasi metafisico del sapere scientifico.

  18. La nuova Carta Geologica d’Italia alla scala 1:1.250.000

    Directory of Open Access Journals (Sweden)

    Marco Pantaloni

    2007-03-01

    Full Text Available Una carta così concepita ha come scopo quello di diffondere in ambito scientifico ma anche, e soprattutto, in ambito didattico, la conoscenza geologica del territorio. L’obiettivo che l’APAT si è impegnato a raggiungere tramite di essa è infatti quello di far arrivare ad un pubblico molto ampio di studiosi, di insegnanti, di studenti e di appassionati, una sintesi delle conoscenze finora raccolte nell’ambito della più recente realizzazione cartografica, la già citata carta geologica alla scala 1:50.000. L’ultima, in ordine di tempo, delle carte a piccola scala realizzate dal Servizio Geologico d’Italia è rappresentata dalla Carta Geologica a scala 1:500.000 pubblicata in 5 fogli durante il periodo 1976-1983.

  19. La teoria della radiazione termica dalla fisica classica alla fisica quantistica

    CERN Document Server

    Planck, Max

    1999-01-01

    La venuta alla luce, nella scienza fisica dei primi anni del Novecento, di elementi assolutamente nuovi prefiguranti il futuro mondo quantistico, è concordemente attribuita all'opera prevalente di Planck e di Einstein, secondo due linee di ricerca profondamente diverse, anche se non lontane risultano le loro concezioni del mondo fisico. Tuttavia, mentre del secondo è facilmente accessibile e sufficientemente nota la produzione scientifica, del primo risulta ancora scarsamente sconosciuta l'ingente produzione di quegli anni, anche perché reperibile, per la maggior parte, solo in lingua originale. Se si tiene presente, inoltre, la comparsa in tempi recenti, della ricostruzione storiografica non tradizionale di T. Kuhn, che ritiene di cogliere, negli scritti di Planck, la permanenza di una struttura integralmente classica fino ad anni successivi al 1906, data di pubblicazione delle Lezioni, risulta naturale convenire sull'opportunità di rendere più agevole l'accesso alle fonti planckiane di quegli anni. ...

  20. Application of lap laser welding technology on stainless steel railway vehicles

    Science.gov (United States)

    Wang, Hongxiao; Wang, Chunsheng; He, Guangzhong; Li, Wei; Liu, Liguo

    2016-10-01

    Stainless steel railway vehicles with so many advantages, such as lightweight, antirust, low cost of maintenance and simple manufacturing process, so the production of high level stainless steel railway vehicles has become the development strategy of European, American and other developed nations. The current stainless steel railway vehicles body and structure are usually assembled by resistance spot welding process. The weak points of this process are the poor surface quality and bad airtight due to the pressure of electrodes. In this study, the partial penetration lap laser welding process was investigated to resolve the problems, by controlling the laser to stop at the second plate in the appropriate penetration. The lap laser welding joint of stainless steel railway vehicle car body with partial penetration has higher strength and surface quality than those of resistance spot welding joint. The biggest problem of lap laser welding technology is to find the balance of the strength and surface quality with different penetrations. The mechanism of overlap laser welding of stainless steel, mechanical tests, microstructure analysis, the optimization of welding parameters, analysis of fatigue performance, the design of laser welding stainless steel railway vehicles structure and the development of non-destructive testing technology were systematically studied before lap laser welding process to be applied in manufacture of railway vehicles. The results of the experiments and study show that high-quality surface state and higher fatigue strength can be achieved by the partial penetration overlap laser welding of the side panel structure, and the structure strength of the car body can be higher than the requirements of En12663, the standard of structural requirements of railway vehicles bodies. Our company has produced the stainless steel subway and high way railway vehicles by using overlap laser welding technology. The application of lap laser welding will be a big

  1. Analysis and optimization of surface profile correcting mechanism of the pitch lap in large-aperture annular polishing

    Science.gov (United States)

    Zhang, Huifang; Yang, Minghong; Xu, Xueke; Wu, Lunzhe; Yang, Weiguang; Shao, Jianda

    2017-10-01

    The surface figure control of the conventional annular polishing system is realized ordinarily by the interaction between the conditioner and the lap. The surface profile of the pitch lap corrected by the marble conditioner has been measured and analyzed as a function of kinematics, loading conditions, and polishing time. The surface profile measuring equipment of the large lap based on laser alignment was developed with the accuracy of about 1μm. The conditioning mechanism of the conditioner is simply determined by the kinematics and fully fitting principle, but the unexpected surface profile deviation of the lap emerged frequently due to numerous influencing factors including the geometrical relationship, the pressure distribution at the conditioner/lap interface. Both factors are quantitatively evaluated and described, and have been combined to develop a spatial and temporal model to simulate the surface profile evolution of pitch lap. The simulations are consistent with the experiments. This study is an important step toward deterministic full-aperture annular polishing, providing a beneficial guidance for the surface profile correction of the pitch lap.

  2. Il museo partecipativo sul web: forme di partecipazione dell’utente alla produzione culturale e alla creazione di valore culturale / The participatory museum on the Web: forms of user participation in cultural production and the creation of cultural value

    Directory of Open Access Journals (Sweden)

    Elisa Bonacini

    2012-05-01

    Full Text Available Obiettivo di questo lavoro è un inquadramento sia del nuovo rapporto fra il museo partecipativo e l’utenza che delle forme di partecipazione dell’utenza alla produzione culturale e alla creazione di valore culturale, alla luce delle potenzialità offerte dalle ICT, soprattutto dal web e dai vari social media. Questo nuovo rapporto, che ha le sue radici più profonde proprio nell’ampia adozione di tutte le piattaforme tecnologiche oggi in uso, consente anche una reinterpretazione del significato stesso di cultural value. Il quadro, che viene qui delineato ed arricchito da numerosi esempi soprattutto stranieri, chiarisce anche quanto l’aspetto partecipativo e l’utilizzo di tags, folksonomie e user generated contents possano incidere sulla fidelizzazione dell’utenza. Infine, in una tabella presentata a fine del contributo, si evidenziano le maggiori componenti che caratterizzano il definitivo passaggio dalla fase Museo 1.0 alla fase Museo 2.0. The aim of this paper is a framework both of the new relationship between the participatory museum and the audience and a framework of multiple forms of audience participation in cultural production and in the creation of cultural value, given the potential offered by ICTs, especially the web and various social media. This new relationship, which has its deepest roots just in the adoption of all technology platforms in use today, also allows for a reinterpretation of the meaning of cultural value. The framework, outlined here and enriched by numerous examples especially foreigners, also makes clear that participation and use of tags, folksonomies and user-generated contents may have an impact on users loyalty. Finally, presented in a table at the end of the paper, we highlight the most important features characterizing the transition from the Museum 1.0 phase to the Museum 2.0 one.

  3. Performance of lap splices in large-scale column specimens affected by ASR and/or DEF-extension phase.

    Science.gov (United States)

    2015-03-01

    A large experimental program, consisting of the design, construction, curing, exposure, and structural load : testing of 16 large-scale column specimens with a critical lap splice region that were influenced by varying : stages of alkali-silica react...

  4. Fatigue Damage Monitoring of a Composite Step Lap Joint Using Distributed Optical Fibre Sensors

    Science.gov (United States)

    Wong, Leslie; Chowdhury, Nabil; Wang, John; Chiu, Wing Kong; Kodikara, Jayantha

    2016-01-01

    Over the past few decades, there has been a considerable interest in the use of distributed optical fibre sensors (DOFS) for structural health monitoring of composite structures. In aerospace-related work, health monitoring of the adhesive joints of composites has become more significant, as they can suffer from cracking and delamination, which can have a significant impact on the integrity of the joint. In this paper, a swept-wavelength interferometry (SWI) based DOFS technique is used to monitor the fatigue in a flush step lap joint composite structure. The presented results will show the potential application of distributed optical fibre sensor for damage detection, as well as monitoring the fatigue crack growth along the bondline of a step lap joint composite structure. The results confirmed that a distributed optical fibre sensor is able to enhance the detection of localised damage in a structure. PMID:28773496

  5. Reliability Analysis for Adhesive Bonded Composite Stepped Lap Joints Loaded in Fatigue

    DEFF Research Database (Denmark)

    Kimiaeifar, Amin; Sørensen, John Dalsgaard; Lund, Erik

    2012-01-01

    -1, where partial safety factors are introduced together with characteristic values. Asymptotic sampling is used to estimate the reliability with support points generated by randomized Sobol sequences. The predicted reliability level is compared with the implicitly required target reliability level defined......This paper describes a probabilistic approach to calculate the reliability of adhesive bonded composite stepped lap joints loaded in fatigue using three- dimensional finite element analysis (FEA). A method for progressive damage modelling is used to assess fatigue damage accumulation and residual...... by the wind turbine standard IEC 61400-1. Finally, an approach for the assessment of the reliability of adhesive bonded composite stepped lap joints loaded in fatigue is presented. The introduced methodology can be applied in the same way to calculate the reliability level of wind turbine blade components...

  6. Experimental Study on Steel to FRP Bonded Lap Joints in Marine Applications

    Directory of Open Access Journals (Sweden)

    Çiçek Özes

    2015-01-01

    Full Text Available Steel structures coated with fiber-reinforced polymer (FRP composites have gained wide acceptance in marine industry due to their high strength-to-weight ratio, good protection from environmental degradation, and impact loads. In this study, adhesive bonding performance of single-lap bonded joints composed of steel coated with FRP has been investigated experimentally for three different surface roughness and two epoxy types. Single-lap bonded joints have been tested under tensile loading. The adhesive bonding performance has been evaluated by calculating the strain energy values. The results reveal that the surface roughness of steel has a significant effect on the bonding performance of steel to FRP combinations and the performance of the resin can be improved by using the primer in an economical way.

  7. Influence of friction stir welding parameters on titanium-aluminum heterogeneous lap joining configuration

    Science.gov (United States)

    Picot, Florent; Gueydan, Antoine; Hug, Éric

    2017-10-01

    Lap joining configuration for Friction Stir Welding process is a methodology mostly dedicated to heterogeneous bonding. This welding technology was applied to join pure titanium with pure aluminum by varying the rotation speed and the movement speed of the tool. Regardless of the process parameters, it was found that the maximum strength of the junction remains almost constant. Microstructural observations by means of Scanning Electron Microscopy and Energy Dispersive Spectrometry analysis enable to describe the interfacial join and reveal asymmetric Cold Lap Defects on the sides of the junction. Chemical analysis shows the presence of one exclusive intermetallic compound through the interface identified as TiAl3. This compound is responsible of the crack spreading of the junction during the mechanical loading. The original version of this article supplied to AIP Publishing contained an accidental inversion of the authors, names. An updated version of this article, with the authors names formatted correctly was published on 20 October 2017.

  8. X-ray method for studying butt gapp distribution and spliced joints in lapped paper and plastic cables

    International Nuclear Information System (INIS)

    Muller, A.C.

    1976-01-01

    Accurate taping patterns are essential in paper and plastic lapped underground cables. A newly developed radiographic system makes it possible to examine the structure of cables and splices in a nondestructive manner. This technique appears to be an effective tool for use in both the monitoring of the accuracy of lapping techniques and as an aid in locating defective portions of existing cables. A discussion of the method and some preliminary results are reported

  9. Le Comunità greca e illirica di Trieste: dalla separazione ecclesiastica alla collaborazione economica (XVIII - XIX secolo)

    OpenAIRE

    Miklic, Vanja

    2014-01-01

    2012/2013 Nel XVIII secolo, in seguito alla dichiarazione del Porto franco, Trieste si trasformò in una città-porto cosmopolita. Le nuove comunità etnico-religiose, e in particolar modo i greci, gli illirici e gli ebrei usufruirono della favorevole politica economica, dei privilegi commerciali ma soprattutto dell’alto livello di tolleranza religiosa garantiti dal governo asburgico. Questo atteggiamento imperiale contribuì a consolidare la fiducia delle comunità immigrate nel governo centra...

  10. Little dragons prefer flowers to maidens: a lizard that laps nectar and pollinates trees

    OpenAIRE

    Sazima, Ivan; Sazima, Cristina; Sazima, Marlies

    2005-01-01

    Lizards rarely visit and pollinate flowers, the few recent records being mostly restricted to island habitats. We report here on the Noronha skink (Euprepis atlanticus) seeking nectar in the flowers of the leguminous mulungu tree (Erythrina velutina) at Fernando de Noronha Archipelago, off northeast Brazil. The mulungu tree blooms during the dry season, and each flower secretes copious and diluted nectar throughout the day. The Noronha skink climbs up to the inflorescences and laps the nectar...

  11. Seawater Durability of Nano-Montmorillonite Modified Single-Lap Joining Epoxy Composite Laminates

    OpenAIRE

    ULUS, Hasan; KAYBAL, Halil Burak; DEMİR, Okan; TATAR, Ahmet Caner; SENYURT, Muhammed Ali; AVCI, Ahmet

    2018-01-01

    The objective of this study was to investigate of nano-montmorillonite modified epoxy composite single-lap bonded joints, after being exposed to seawater immersion in order to understand the effect of seawater environment on their performance. To prepare the nano adhesives, nano montmorillonite (2 wt %) was incorporated into epoxy resin. Composite bonded specimens which manufactured with VARIM (Vacuum Assisted Resin Infusion Method) were prepared accordance with ASTM D5868-01 and immersed in ...

  12. Structural assessment of a lapped scarf joint applied to historical timber constructions in central Europe

    Czech Academy of Sciences Publication Activity Database

    Kunecký, Jiří; Hasníková, Hana; Kloiber, Michal; Milch, J.; Sebera, V.; Tippner, J.

    2018-01-01

    Roč. 12, č. 4 (2018), s. 666-682 ISSN 1558-3058 R&D Projects: GA MK(CZ) DG16P02M026 Keywords : carpentry * design limit state * lap joint * numerical modeling * stiffness Subject RIV: AL - Art, Architecture, Cultural Heritage OBOR OECD: Construction engineering, Municipal and structural engineering Impact factor: 1.053, year: 2016 https://www.tandfonline.com/doi/full/10.1080/15583058.2018.1442524

  13. Single-Lap-Joint Screening of Hysol EA 9309NA Epoxy Adhesive

    Science.gov (United States)

    2017-05-01

    Acknowledgments This research was supported in part by the US Army Education Outreach Programs (Science and Engineering Apprentice Program and College...useful for estimating downstream logistical phase- out risk based on current and pending environmental regulations . Second-tier testing consists of...was used to ensure that the breaking load of single-lap-joint samples fell between 15% and 85% of the cell’s full-scale capacity. A crosshead speed

  14. Seismic fragility analysis of lap-spliced reinforced concrete columns retrofitted by SMA wire jackets

    International Nuclear Information System (INIS)

    Choi, Eunsoo; Park, Sun-Hee; Chung, Young-Soo; Kim, Hee Sun

    2013-01-01

    The aim of this study is to provide seismic fragility curves of reinforced concrete columns retrofitted by shape memory alloy wire jackets and thus assess the seismic performance of the columns against earthquakes, comparing them with reinforced concrete columns with lap-spliced and continuous reinforcement. For that purpose, this study first developed analytical models of the experimental results of the three types of columns, (1) lap-spliced reinforcement, (2) continuous reinforcement and (3) lap-spliced reinforcement and retrofitted by SMA wire jackets, using the OpenSEES program, which is oriented to nonlinear dynamic analysis. Then, a suite of ten recorded ground motions was used to conduct dynamic analyses of the analytical models with scaling of the peak ground acceleration from 0.1g to 1.0g in steps of 0.1g. From the static experimental tests, the column retrofitted with SMA wire jackets had a larger displacement ductility by a factor of 2.3 times that of the lap-spliced column, which was 6% larger compared with the ductility of the continuous reinforcement column. From the fragility analyses, the SMA wire jacketed column had median values of 0.162g and 0.567g for yield and collapse, respectively. For the yield damage state, the SMA wire jacketed column had a median value similar to the continuous reinforcement column. However, for the complete damage state, the SMA wire jacketed column showed a 1.33 times larger median value than the continuously reinforcement column. (paper)

  15. Real-time monitoring of laser welding of galvanized high strength steel in lap joint configuration

    Science.gov (United States)

    Kong, Fanrong; Ma, Junjie; Carlson, Blair; Kovacevic, Radovan

    2012-10-01

    Two different cases regarding the zinc coating at the lap joint faying surface are selected for studying the influence of zinc vapor on the keyhole dynamics of the weld pool and the final welding quality. One case has the zinc coating fully removed at the faying surface; while the other case retains the zinc coating on the faying surface. It is found that removal of the zinc coating at the faying surface produces a significantly better weld quality as exemplified by a lack of spatters whereas intense spatters are present when the zinc coating is present at the faying surface. Spectroscopy is used to detect the optical spectra emitted from a laser generated plasma plume during the laser welding of galvanized high strength DP980 steel in a lap-joint configuration. A correlation between the electron temperature and defects within the weld bead is identified by using the Boltzmann plot method. The laser weld pool keyhole dynamic behavior affected by a high-pressure zinc vapor generated at the faying surface of galvanized steel lap-joint is monitored in real-time by a high speed charge-coupled device (CCD) camera assisted with a green laser as an illumination source.

  16. Effects of composite adherend properties on stresses in double lap bonded joints

    International Nuclear Information System (INIS)

    Mokhtari, M.; Madani, K.; Belhouari, M.; Touzain, S.; Feaugas, X.; Ratwani, M.

    2013-01-01

    Highlights: ► We analysis the maximal stresses distribution in the adhesive and the adherend for double lap joint. ► We modified the mechanical properties of adherend layer to decreases the stresses in adhesive layer. ► Then, we analysis the influence of modifying the types of fibers on maximal stresses distributions. ► We analysis the thickness modifications of some layers on maximal stresses distribution. ► In last, we analysis the combination of different modifications on maximal stresses distribution. -- Abstract: The effects of composite layer stiffness, thickness and ply orientations on stresses in the adhesive layer of a double lap bonded joint are investigated using three-dimensional finite element analysis code ABAQUS. A special 3-layer modelling technique is used in the finite element analysis. The non-linear behaviour of adhesive is also considered. Six composite laminates with different ply orientations are used in the lap-joint analysis. The composite materials considered in the analysis are – carbon epoxy, boron epoxy, T300/934 graphite-epoxy, and aramid epoxy. The analysis results indicate that the maximum stress in the adhesive can be significantly reduced by changing the stiffness and fibre orientations in the composite layer. Also, the use of hybrid composite (changing the nature of the fibres in two layers which are near the adhesive layer) results in reducing adhesive shear stresses.

  17. Effect of Thread and Rotating Speed on Material Flow Behavior and Mechanical Properties of Friction Stir Lap Welding Joints

    Science.gov (United States)

    Ji, Shude; Li, Zhengwei; Zhou, Zhenlu; Wu, Baosheng

    2017-10-01

    This study focused on the effects of thread on hook and cold lap formation, lap shear property and impact toughness of alclad 2024-T4 friction stir lap welding (FSLW) joints. Except the traditional threaded pin tool (TR-tool), three new tools with different thread locations and orientations were designed. Results showed that thread significantly affected hook, cold lap morphologies and lap shear properties. The tool with tip-threaded pin (T-tool) fabricated joint with flat hook and cold lap, which resulted in shear fracture mode. The tools with bottom-threaded pin (B-tool) eliminated the hook. The tool with reverse-threaded pin (R-tool) widened the stir zone width. When using configuration A, the joints fabricated by the three new tools showed higher failure loads than the joint fabricated by the TR-tool. The joint using the T-tool owned the optimum impact toughness. This study demonstrated the significance of thread during FSLW and provided a reference to optimize tool geometry.

  18. Il giorno della laurea di Giovanni Meola. Dal testo alla scena

    Directory of Open Access Journals (Sweden)

    Armando Rotondi

    2016-06-01

    Full Text Available Quando Giovanni Meola, drammaturgo e regista indipendente, mi ha chiesto di seguire la genesi de Il giorno della laurea, andato poi in scena con Cristiana Dell‟Anna ed Enrico Ottaviano dal 26 aprile al 1 maggio 2016 presso la Sala Ridotto del Teatro Stabile di Napoli-Teatro Nazionale (noto molte volte semplicemente come Teatro Mercadante, ho accettato con grande entusiasmo. E seppure io abbia avuto modo di seguire solo parzialmente le prove, ho raccolto comunque materiale prezioso per questa piccola monografia. Il lavoro critico che segue è stato anticipato da una serie di articoli giornalistici da me firmati e pubblicati su “EffettoNapoli.it” il 17, il 24 e il 30 Aprile e da un seminario dal titolo “Nuova letteratura drammatica contemporanea – Incontro con Giovani Meola, Cristiana Dell‟Anna ed Enrico Ottaviano” (28 aprile 2016, da me organizzato e che si è svolto nell'ambito dell‟insegnamento di Letteratura Italiana presso l‟Università degli Studi di Napoli “L‟Orientale”. Nell'approcciarmi alla stesura di questa breve monografia, ho utilizzato pertanto i precedenti articoli come primo schema per ampliare alcuni elementi che, in taluni casi, erano stati appena toccati per motivi propri di spazio, necessariamente limitato nel giornalismo on-line.

  19. Vestite alla turchesca. Travestimenti orientali nella drammaturgia italiana e francese tra Sei e Settecento

    Directory of Open Access Journals (Sweden)

    Stefano Agostino Moretti

    2011-11-01

    Full Text Available Da secoli il Mar Mediterraneo rappresenta un confine tra due mondi. Gli orientalisti li chiamavano e continuano a chiamarli mondo “arabo” e mondo “cristiano”. Questo contributo vuole mostrare come, in tempi non sospetti, l’Italia rappresentasse un ponte tra queste due culture. Grazie agli strumenti della storiografia contemporanea, attenta alla vita quotidiana e agli “archivi del corpo”, scopriamo che durante il XVI e il XVII secolo gli incontri tra musulmani e cristiani fossero molto frequenti e spesso felici. Il teatro comico italiano fu il genere letterario che, prima e meglio di ogni altro, riuscì a cogliere e a descrivere tale fenomeno con tutte le implicazioni politiche, religiose e identitarie, restituendone in pieno uno degli elementi sovente sottaciuti e censurati, ovvero la perturbante carica erotica del “diverso”. Uno degli espedienti che riassumono con maggiore efficacia questo  rapporto identitario e culturale è rappresentato dall’uso del travestimento. Paragonando alcune commedie italiane della prima metà del Seicento con il teatro “orientalista” di Bonarelli, Molière e Goldoni, possiamo osservare la nascita e la crescita di una visione stereotipata e libresca dell’altro, là dove i “panni turcheschi” generavano negli spettatori paura e desiderio.

  20. Crystallography of hornblende amphibole in LAP04840 R chondrite and implication for its metamorphic history

    International Nuclear Information System (INIS)

    Ota, Kouhei; Mikouchi, Takashi; Sugiyama, Kazumasa

    2009-01-01

    LAP04840 is an unusual R chondrite that includes abundant hornblende amphibole. LAP04840 shows a texture of equilibrated chondrite composed of 59.3% olivine, 13.5% orthopyroxene, 13.3% hornblende, 6.2% plagio-clase, 6.0% Fe-Ni sulfide, and 1.7% accessory minerals. Hornblende replaces olivine and pyroxene in both chondrules and matrices, suggesting its secondary origin. All major phases in LAP04840 are homogeneous: olivine (Fa 37 ), orthopyroxene (En 70 Wo 1 ), and plagioclase (An 8 Or 2 ). Hornblende is also nearly homogeneous, but the total sum by electron microprobe analysis is 96-98 wt%, suggesting the presence of Fe 3+ and a hydroxyl group. Synchrotron Fe-XANES analysis gives a Fe 3+ /ΣFe ratio of ∼0.6 and micro-FT-IR analysis confirms the presence of a hydroxyl group. Thus, the structural formula is (Na 0.40 K 0 . 04 ) (Ca 1.46 Mn 0.02 Fe 0.06 2+ Na 0.46 ) (Al 0.08 Fe 0.43 2+ Fe 0.75 3+ Cr 0.08 Mg 3.60 ) (Si 7.02 Al 0.98 )O 22 (OH) 2 . Single crystal X-ray diffraction of LAP04840 hornblende gives the following lattice constants: a=9.7957(9) A, b=18.0788(12) A, c=5.2949(5) A, β=104.747(3)deg. The relatively short distances of [M(1)-O=2.069 A], [M(2)-O=2.081 A], and [M(3)-O=2.058 A] suggest the feasible preference of small Fe 3+ at these sites. The mineralogy and petrology of LAP04840 are consistent with its classification as an R6 chondrite. However, the presence of hornblende and biotite is quite unique among not only R chondrites but also asteroidal meteorites in general. The presence of these hydrous minerals suggests metamorphism under high pressure and an aqueous environment probably at depth in the parent body. A thermometer using hornblende and plagioclase equilibria gives T=670-690degC. Further, a barometer using Al content in hornblende gives P=∼0.1 GPa. Although these estimates bear some uncertainties, it is likely that the size of the R chondrite parent body was large enough to induce such metamorphism. (author)

  1. The role of haptic feedback in laparoscopic training using the LapMentor II.

    Science.gov (United States)

    Salkini, Mohamad W; Doarn, Charles R; Kiehl, Nicholai; Broderick, Timothy J; Donovan, James F; Gaitonde, Krishnanath

    2010-01-01

    Laparoscopic surgery has become the standard of care for many surgical diseases. Haptic (tactile) feedback (HFB) is considered an important component of laparoscopic surgery. Virtual reality simulation (VRS) is an alternative method to teach surgical skills to surgeons in training. Newer VRS trainers such as the Simbionix Lap Mentor II provide significantly improved tactile feedback. However, VRSs are expensive and adding HFB software adds an estimated cost of $30,000 to the commercial price. The HFB provided by the Lap Mentor II has not been validated by an independent party. We used the Simbionix Lap Mentor II in this study to demonstrate the effect of adding an HFB mechanism in the VRS trainer. The study was approved by the University of Cincinnati Institutional Review Board. Twenty laparoscopically novice medical students were enrolled. Each student was asked to perform three different tasks on the Lap Mentor II and repeat each one five times. The chosen tasks demanded significant amount of traction and counter traction. The first task was to pull leaking tubes enough and clip them. The second task was stretching a jelly plate enough to see its attachments to the floor and cut these attachments. In the third task, the trainee had to separate the gallbladder from its bed on the liver. The students were randomized into two groups to perform the tasks with and without HFB. We used accuracy, speed, and economy of movement as scales to compare the performance between the two groups. The participants also completed a simple questionnaire that highlighted age, sex, and experiences in videogame usage. The two groups were comparable in age, sex, and videogame playing. No differences in the accuracy, the economy, and the speed of hand movement were noticed. In fact, adding HFB to the Lap Mentor II simulator did not contribute to any improvement in the performance of the trainees. Interestingly, we found that videogame expert players tend to have faster and more economic

  2. A multi-feature integration method for fatigue crack detection and crack length estimation in riveted lap joints using Lamb waves

    Data.gov (United States)

    National Aeronautics and Space Administration — This paper presents an experimental study of damage detection and quantification in riveted lap joints. Embedded lead zirconate titanate piezoelectric (PZT) ceramic...

  3. I beni immobili confiscati alla criminalità organizzata in Lombardia

    Directory of Open Access Journals (Sweden)

    Mattia Maestri

    2016-07-01

    Full Text Available L’articolo compie una ricognizione della presenza e della distribuzione geografica dei beni immobili confiscati alla criminalità organizzata in Lombardia. Ne propone un’analisi quantitativa, utilizzando i dati messi a disposizione da ANBSC (Agenzia Nazionale dei Beni Sequestrati e Confiscati e da Libera Lombardia. E integra questa prospettiva con una analisi qualitativa condotta sul campo che permette di evidenziare significativi esempi di best practices nel riutilizzo sociale degli stessi beni. Nell’ambito di questa sezione della ricerca vengono anche considerati alcuni fondamentali indicatori: le caratteristiche strutturali del bene immobile, il suo rapporto con la memoria collettiva, la sua notorietà pubblica e le funzioni e le attività che vi vengono svolte. Ne emerge un modello lombardo del riuso sociale contrassegnato da alcune interessanti criticità. The paper analyzes the presence and the geographical distribution of real estate confiscated assets from organized crime. Using data made available by The National Agency of Confiscated Property and Libera association, it provides a quantitative analysis integrated with a qualitative approach on the field with the purpose to highlight examples of best practices in the social re-use of these confiscated assets. In this qualitative analysis are also taken into account some key indicators: the asset’s structural features, its relationship with memory, its public reputation and the activities made inside it. Finally, it emerges a Lombard model of social reuse marked by some interesting criticalities. Key words: Confiscated property, Lombardy, Social business, Best practices, Memory

  4. Il sorriso del conte zio. Manzoni, Sade e l’omaggio alla Vergine

    Directory of Open Access Journals (Sweden)

    Fabio Camilletti

    2016-07-01

    Full Text Available Il saggio esamina la figura della Lucia di Manzoni alla luce del ‘tipo’ letterario della ‘fanciulla perseguitata’, al crocevia fra agiografia, letteratura libertina, romanzo sentimentale, narrativa gotica e letteratura romantica. In particolare si sofferma, anche attraverso un’analisi comparata dei frontespizi de I promessi sposi e dell’edizione del 1791 di Justine, sulle affinità e le divergenze fra la Lucia di Manzoni e l’eroina di Sade, sostenendone la parentela intertestuale e la specularità, nell’essere entrambe risposte (solo apparentemente antitetiche al problema metafisico del male. In questo senso si sottolinea l’influenza, su Manzoni e Sade, del modello mariano, nei decenni in cui si assiste, per reazione al laicismo illuminista e rivoluzionario, a un rinnovato culto per la Vergine, che culminerà con il dogma dell’Immacolata Concezione (1854 e le apparizioni di Lourdes (1858.   The essay examines the figure of Manzoni’s Lucia in the light of the literary ‘type’ of the ‘persecuted maiden’, at the intersection between hagiography, libertine literature, sentimental novel, Gothic narrative, and Romantic literature. In particular, through a comparative analysis of the frontispieces of I promessi sposi and of the 1791 edition of Justine, it focuses on the similarities and differences between Manzoni’s Lucia and Sade’s eponymous heroine, arguing for an intertextual relationship between the two and suggesting their reciprocal specularity, in being both answers (only apparently antithetical to the metaphysical problem of evil. From this angle, the essay analyzes the influence, on both Manzoni and Sade, of the figure of Mary, in the years witnessing – as a reaction against the secularization promoted by the Enlightenment and the French revolution – to a renewed worship for the Holy Virgin, later culminating in the promulgation of the Immaculate Conception dogma (1854 and the apparitions at Lourdes (1858.

  5. Disputa teologica in un mondo alla rovescia: il dramma su Abramo di Moshè Zacuto

    Directory of Open Access Journals (Sweden)

    Ariel Rathaus

    2011-06-01

    The foundation of the world (Yessod 'Olam is believed to be the first Biblical drama written in Hebrew.  It was composed in the first half of the 17th century by the mystical and rabbinical author Moshe Zacuto, who immigrated to Italy from Amsterdam.  In fact the work is mostly based on rabbinic legends about Abraham and his struggle against idolatry, and includes many theological debates between the patriarch and King Nimrod, the pagan tyrant who condemns him to be burnt for his ideas. This paper deals with the ideological background of the drama and the peculiar and paradoxical atmosphere created by the theological debates.  As asserted by several scholars (Berliner, Schirmann. Levy, Zacuto, who was born in a refugees family of  Marrano origin,  alluded in his play to the persecutions of the Jews by the Inquisition in Spain and Portugal. On the other hand, it seems that the play also alludes to 17th Century materialistic philosophy and hedonism, symbolized by the words of Nimrod and his sages.  At any rate, the struggle between Abraham and Nimrod takes place in a highly absurd ideological frame, in which right and wrong are meaningless concepts and true faith is considered as a sort of moral perversion: a reversed world. The paper underlines this hidden and ironic aspect of the play and discusses it, on the basis of some classic works on Carnival reversion, like Cocchiara's Il mondo alla rovescia  and Bakhtin' s Rabelais and his world.

  6. One hundred cases of laparoscopic subtotal hysterectomy using the PK and Lap Loop systems.

    Science.gov (United States)

    Erian, John; El-Toukhy, Tarek; Chandakas, Stefanos; Theodoridis, Theo; Hill, Nicholas

    2005-01-01

    To evaluate the safety and short-term outcomes of laparoscopic subtotal hysterectomy using the PK and Lap Loop systems. Prospective observational study (Canadian Task Force classification II-2). Princess Royal University and Chelsfield Park Hospitals, Kent, UK. One hundred women who underwent laparoscopic subtotal hysterectomy for menorrhagia from February 2003 through July 2004. The procedure was performed using the Plasma Kinetic (PK) system to seal the vascular pedicles and the Lap Loop system to separate the uterus at the level of the internal os. The uterus was removed from the abdominal cavity mainly by morcellation or posterior colpotomy. Of 100 patients, 59 were operated on as outpatients. Mean patient age was 44.6 years, median parity was 2, mean body mass index was 26.8, and mean duration of symptoms was 4 years. Clinically, the uterus was enlarged in 70 patients, and preoperative ultrasound scanning suggested the presence of uterine myomas in 42 patients. In addition to hysterectomy, 47 patients had concomitant pelvic surgery. The mean total operating time was 45.5 minutes, and mean estimated blood loss was 114 mL. The overall major complication rate was 2%; two patients required blood transfusion after surgery. There were no bowel or urinary tract injuries, unintended laparotomy, return to operating room, or anesthetic complications. At follow-up, all patients were satisfied with surgery. Laparoscopic subtotal hysterectomy using the PK and Lap Loop systems for treatment of therapy-resistant menorrhagia is safe, can be performed as an outpatient procedure, and is associated with reduced operating time and high patient satisfaction.

  7. Construct validity of the LapVR virtual-reality surgical simulator.

    Science.gov (United States)

    Iwata, Naoki; Fujiwara, Michitaka; Kodera, Yasuhiro; Tanaka, Chie; Ohashi, Norifumi; Nakayama, Goro; Koike, Masahiko; Nakao, Akimasa

    2011-02-01

    Laparoscopic surgery requires fundamental skills peculiar to endoscopic procedures such as eye-hand coordination. Acquisition of such skills prior to performing actual surgery is highly desirable for favorable outcome. Virtual-reality simulators have been developed for both surgical training and assessment of performance. The aim of the current study is to show construct validity of a novel simulator, LapVR (Immersion Medical, San Jose, CA, USA), for Japanese surgeons and surgical residents. Forty-four subjects were divided into the following three groups according to their experience in laparoscopic surgery: 14 residents (RE) with no experience in laparoscopic surgery, 14 junior surgeons (JR) with little experience, and 16 experienced surgeons (EX). All subjects executed "essential task 1" programmed in the LapVR, which consists of six tasks, resulting in automatic measurement of 100 parameters indicating various aspects of laparoscopic skills. Time required for each task tended to be inversely correlated with experience in laparoscopic surgery. For the peg transfer skill, statistically significant differences were observed between EX and RE in three parameters, including total time and average time taken to complete the procedure and path length for the nondominant hand. For the cutting skill, similar differences were observed between EX and RE in total time, number of unsuccessful cutting attempts, and path length for the nondominant hand. According to the programmed comprehensive evaluation, performance in terms of successful completion of the task and actual experience of the participants in laparoscopic surgery correlated significantly for the peg transfer (P=0.007) and cutting skills (P=0.026). The peg transfer and cutting skills could best distinguish between EX and RE. This study is the first to provide evidence that LapVR has construct validity to discriminate between novice and experienced laparoscopic surgeons.

  8. Using quantum dots to tag subsurface damage in lapped and polished glass samples

    International Nuclear Information System (INIS)

    Williams, Wesley B.; Mullany, Brigid A.; Parker, Wesley C.; Moyer, Patrick J.; Randles, Mark H.

    2009-01-01

    Grinding, lapping, and polishing are finishing processes used to achieve critical surface parameters in a variety of precision optical and electronic components. As these processes remove material from the surface through mechanical and chemical interactions, they may induce a damaged layer of cracks, voids, and stressed material below the surface. This subsurface damage (SSD) can degrade the performance of a final product by creating optical aberrations due to diffraction, premature failure in oscillating components, and a reduction in the laser induced damage threshold of high energy optics. As these defects lie beneath the surface, they are difficult to detect, and while many methods are available to detect SSD, they can have notable limitations regarding sample size and type, preparation time, or can be destructive in nature. The authors tested a nondestructive method for assessing SSD that consisted of tagging the abrasive slurries used in lapping and polishing with quantum dots (nano-sized fluorescent particles). Subsequent detection of fluorescence on the processed surface is hypothesized to indicate SSD. Quantum dots that were introduced to glass surfaces during the lapping process were retained through subsequent polishing and cleaning processes. The quantum dots were successfully imaged by both wide field and confocal fluorescence microscopy techniques. The detected fluorescence highlighted features that were not observable with optical or interferometric microscopy. Atomic force microscopy and additional confocal microscope analysis indicate that the dots are firmly embedded in the surface but do not appear to travel deep into fractures beneath the surface. Etching of the samples exhibiting fluorescence confirmed that SSD existed. SSD-free samples exposed to quantum dots did not retain the dots in their surfaces, even when polished in the presence of quantum dots.

  9. Handheld multi-channel LAPS device as a transducer platform for possible biological and chemical multi-sensor applications

    International Nuclear Information System (INIS)

    Wagner, Torsten; Molina, Roberto; Yoshinobu, Tatsuo; Kloock, Joachim P.; Biselli, Manfred; Canzoneri, Michelangelo; Schnitzler, Thomas; Schoening, Michael J.

    2007-01-01

    The light-addressable potentiometric sensor is a promising technology platform for multi-sensor applications and lab-on-chip devices. However, many prior LAPS developments suffer from their lack in terms of non-portability, insufficient robustness, complicate handling, etc. Hence, portable and robust LAPS-based measurement devices have been investigated by the authors recently. In this work, a 'chip card'-based light-addressable potentiometric sensor system is presented. The utilisation of ordinary 'chip cards' allows an easy handling of different sensor chips for a wide range of possible applications. The integration of the electronic and the mechanical set-up into a single reader unit results in a compact design with the benefits of portability and low required space. In addition, the presented work includes a new multi-frequency measurement procedure, based on an FFT algorithm, which enables the simultaneous real-time measurement of up to 16 sensor spots. The comparison between the former batch-LAPS and the new FFT-based LAPS set-up will be presented. The immobilisation of biological cells (CHO: Chinese hamster ovary) demonstrates the possibility to record their metabolic activity with 16 measurement spots on the same chip. Furthermore, a Cd 2+ -selective chalcogenide-glass layer together with a pH-sensitive Ta 2 O 5 layer validates the use of the LAPS for chemical multi-sensor applications

  10. Assessment of vitamin D status and serum CrossLaps levels in adults with primary lactose malabsorption.

    Science.gov (United States)

    Enko, D; Kriegshäuser, G; Stolba, R; Mangge, H; Brandstetter, D; Mayr, N; Forstner, T; Halwachs-Baumann, G

    2016-09-01

    Primary adult-type lactose malabsorption (PALM) is a widespread inherited autosomal recessive condition, which is considered to be associated with osteoporosis. This prospective study aimed at assessing the 25-hydroxy-vitamin D (25(OH)D) status and serum CrossLaps levels in individuals with PALM and normal controls. All participants (n=210) underwent genotyping for the LCT C/T-13910 polymorphism, 25(OH)D and CrossLaps measurements and clinical examinations. In addition, the anthropometric data (that is, height, weight and body mass index) were determined. Fifty-five individuals with PALM (that is, LCT C/C-13910 homozygotes) showed lower 25(OH)D (mean: 24.95±10.04 vs 28.59±9.56 ng/ml, P=0.018) and higher CrossLaps serum levels (mean: 0.46±0.31 vs 0.43±0.49 ng/ml, P=0.251) compared with 155 normal controls (that is, LCT C/T-13910 hetero- or T/T-13910 homozygotes). Anthropometric data were similar between PALM probands and controls. Individuals with PALM were found to have lower 25(OH)D and higher CrossLaps serum levels compared with normal controls. In order to preserve life-long bone health, routine 25(OH)D and CrossLaps serum measurements should be performed in individuals with PALM.

  11. Mechanisms of the porosity formation during the fiber laser lap welding of aluminium alloy

    Directory of Open Access Journals (Sweden)

    J. Wang

    2015-10-01

    Full Text Available When joining the aluminum alloys, one of the biggest challenges is the formation of porosity, which deteriorates mechanical properties of welds. In this study, the lap welding was conducted on an aluminum alloy 5754 metal sheets with a thickness of 2 mm. The effects of various laser welding parameters on the weld quality were investigated. The porosity content was measured by X-ray inspections. The key is to control the solidification duration of molten pool. When the solidification duration of molten pool is large enough, more bubbles can escape from the molten pool and less remain as porosity.

  12. Behavior of single lap composite bolted joint under traction loading: Experimental investigation

    Science.gov (United States)

    Awadhani, L. V.; Bewoor, Anand

    2018-04-01

    Composite bolted joints are preferred connection in the composite structures to facilitate the dismantling for the replacements/ maintenance work. The joint behavior under tractive forces has been studied in order to understand the safety of the structure designed. The main objective of this paper is to investigate the behavior of single-lap joints in carbon fiber reinforced epoxy composites under traction loading conditions. The experiments were designed to identify the effect of bolt diameter, stacking sequence and loading rate on the properties of the joint. The experimental results show that the parameters influence the joint performance significantly.

  13. Determination of L-AP4-bound human mGlu8 receptor amino terminal domain structure and the molecular basis for L-AP4’s group III mGlu receptor functional potency and selectivity

    Energy Technology Data Exchange (ETDEWEB)

    Schkeryantz, Jeffery M.; Chen, Qi; Ho, Joseph D.; Atwell, Shane; Zhang, Aiping; Vargas, Michelle C.; Wang, Jing; Monn, James A.; Hao, Junliang (Lilly)

    2018-02-01

    Here, L-2-Amino-4-phosphonobutyric acid (L-AP4) is a known potent and selective agonist for the Group III mGlu receptors. However, it does not show any selectivity among the individual group III mGlu subtypes. In order to understand the molecular basis for this group selectivity, we solved the first human mGlu8 amino terminal domain (ATD) crystal structures in complex with L-glu and L-AP4. In comparison with other published L-glu-bound mGlu ATD structures, we have observed L-glu binds in a significantly different manner in mGlu1. Furthermore, these new structures provided evidence that both the electronic and steric nature of the distal phosphate of L-AP4 contribute to its exquisite Group III functional agonist potency and selectivity.

  14. Lap time simulation and design optimisation of a brushed DC electric motorcycle for the Isle of Man TT Zero Challenge

    Science.gov (United States)

    Dal Bianco, N.; Lot, R.; Matthys, K.

    2018-01-01

    This works regards the design of an electric motorcycle for the annual Isle of Man TT Zero Challenge. Optimal control theory was used to perform lap time simulation and design optimisation. A bespoked model was developed, featuring 3D road topology, vehicle dynamics and electric power train, composed of a lithium battery pack, brushed DC motors and motor controller. The model runs simulations over the entire ? or ? of the Snaefell Mountain Course. The work is validated using experimental data from the BX chassis of the Brunel Racing team, which ran during the 2009 to 2015 TT Zero races. Optimal control is used to improve drive train and power train configurations. Findings demonstrate computational efficiency, good lap time prediction and design optimisation potential, achieving a 2 minutes reduction of the reference lap time through changes in final drive gear ratio, battery pack size and motor configuration.

  15. Microstructure and mechanical properties of friction stir lap welded Mg/Al joint assisted by stationary shoulder

    Science.gov (United States)

    Ji, Shude; Li, Zhengwei

    2017-11-01

    Using magnesium alloy as upper sheet, 3 mm-thick AZ31 magnesium alloy and 6061 aluminum alloy were joined using friction stir lap welding assisted by stationary shoulder. The effects of tool rotating speed on cross-sections, microstructure and mechanical properties of Mg/Al lap joints were mainly discussed. Results showed that stationary shoulder contributed to joint formation, by which stir zones (SZ) were characterized by big onion rings after welding. Because of the big forging force exerted by stationary shoulder, the upper region of hook was well bonded. SZ showed much higher hardness because of intermetallic compounds (IMCs). The bonding conditions at the base material (BM)/SZ interface at advancing side and the hook region played important roles on joint lap shear properties. The X-ray diffraction pattern analysis revealed that the main IMCs were Al3Mg2 and Al12Mg17.

  16. L-Cysteine and L-AP4 microinjections in the rat caudal ventrolateral medulla decrease arterial blood pressure.

    Science.gov (United States)

    Takemoto, Yumi

    2014-12-01

    The thiol amino acid L-cysteine increases arterial blood pressure (ABP) when injected into the cerebrospinal fluid space in conscious rats, indicating a pressor response to centrally acting L-cysteine. A prior synaptic membrane binding assay suggests that L-cysteine has a strong affinity for the L-2-amino-4-phosphonobutyric acid (L-AP4) binding site. The central action of L-cysteine may be vial-AP4 sensitive receptors. The present study investigated cardiovascular responses to L-cysteine and L-ap4 microinjected into the autonomic area of the caudal ventrolateral medulla (CVLM) where inhibitory neurons regulate ABP via pre-sympathetic vasomotor neurons. Both the injection of L-cysteine and L-AP4 in the CVLM sites identified with L-glutamate produced the same depressor and bradycardic responses in urethane-anesthetized rats. Neither a prior antagonist microinjection of MK801 for the N-methyl-D-aspartate (NMDA) receptor nor CNQX for the non-NMDA receptor attenuated the responses to L-cysteine, but the combination of the two receptor blocking with an additional prior injection abolished the response. In contrast, either receptor blockade alone abolished the response to L-AP4, indicating distinct mechanisms between responses to L-cysteine and L-AP4 in the CVLM. The results indicate that the CVLM is a central active site for L-cysteine's cardiovascular response. Central L-cysteine's action could be independent of the L-AP4 sensitive receptors. Cardiovascular regulation may involve endogenous L-cysteine in the CVLM. Further multidisciplinary examinations are required to elaborate on L-cysteine's functional roles in the CVLM. Copyright © 2014 Elsevier B.V. All rights reserved.

  17. Impaired circulating CD4+ LAP+ regulatory T cells in patients with acute coronary syndrome and its mechanistic study.

    Directory of Open Access Journals (Sweden)

    Zheng-Feng Zhu

    Full Text Available OBJECTIVE: CD4(+ latency-associated peptide (LAP(+ regulatory T cells (Tregs are a newly discovered T cell subset in humans and the role of these cells in patients with acute coronary syndrome (ACS has not been explored. We designed to investigate whether circulating frequency and function of CD4(+LAP(+ Tregs are defective in ACS. METHODS: One hundred eleven ACS patients (acute myocardial infarction and unstable angina and 117 control patients were enrolled in the study. The control patients consisted of chronic stable angina (CSA and chest pain syndrome (CPS. The frequencies of circulating CD4(+LAP(+ Tregs and the expression of the transmembrane protein glycoprotein-A repetitions predominant (GARP on CD4(+ T cells were determined by flow cytometry. The function of CD4(+LAP(+ Tregs was detected using thymidine uptake. Serum interleukin-10 (IL-10 and transforming growth factor-β protein (TGF-β levels were detected using ELISA and expression of GARP mRNA in peripheral blood mononuclear cells (PBMCs was measured by real time-polymerase chain reaction. RESULTS: We found ACS patients had a significantly lower frequency of circulating CD4(+LAP(+ Tregs, and the function of these cells was reduced compared to controls. The expression of GARP in CD4(+ T cells and the serum levels of TGF-β in ACS patients were lower than those of control patients. The serum levels of IL-10 were similar between the two cohorts. CONCLUSIONS: A novel regulatory T cell subset, defined as CD4(+LAP(+ T cells is defective in ACS patients.

  18. Friction Stir Welding-assisted Diffusion Bond of Al/Zn/Mg Lap Joint

    Directory of Open Access Journals (Sweden)

    JIN Yu-hua

    2018-03-01

    Full Text Available Dissimilar materials welding between 2mm-thick AZ31B Mg alloy and 6061 Al alloy plates in overlap form was performed using the friction stir-induced diffusion bond with zinc foil as the interlayer. The microstructure and mechanical properties of the Al/Zn/Mg lap joints were analyzed by means of SEM, EPMA, XRD, tensile experiment and Vickers hardness test. The results show that diffusion layer consists of Al enrichment zone, Al5Mg11Zn4 layer and Mg-Zn eutectic zone at proper rotation speed; however, when rotation speed is low, the residual zinc interlayer remains in the diffusion layer; when rotation speed is high, the Al-Mg intermetallic compounds are present again. Due to the existence of intermetallic compounds in diffusion layer, its microhardness is significantly higher than that of base metal. The addition of zinc foil can improve the mechanical properties of Al/Mg lap joints. According to analysis on the fracture, joint failure occurs in the diffusion layer near to Al side.

  19. Lap shear strength and healing capability of self-healing adhesive containing epoxy/mercaptan microcapsules

    Energy Technology Data Exchange (ETDEWEB)

    Ghazali, Habibah; Ye, Lin [Centre for Advanced Materials Technology (CAMT), School of Aerospace, Mechanical and Mechatronic Engineering, The University of Sydney, NSW 2006 (Australia); Zhang, Ming-Qiu [Key Laboratory of Polymeric Composite and Functional Materials of Ministry of Education, Zhongshan University, Guangzhou 510275 (China)

    2016-03-09

    The aim of this work is to develop a self-healing polymeric adhesive formulation with epoxy/mercaptan microcapsules. Epoxy/mercaptan microcapsules were dispersed into a commercialize two-part epoxy adhesive for developing self-healing epoxy adhesive. The influence of different content of microcapsules on the shear strength and healing capability of epoxy adhesive were investigated using single-lap-joints with average thickness of adhesive layer of about 180 µm. This self-healing adhesive was used in bonding of 5000 series aluminum alloys adherents after mechanical and alkaline cleaning surface treatment. The adhesion strength was measured and presented as function of microcapsules loading. The results indicated that the virgin lap shear strength was increased by about 26% with addition of 3 wt% of self-healing microcapsules. 12% to 28% recovery of the shear strength is achieved after self-healing depending on the microcapsules content. Scanning electron microscopy was used to study fracture surface of the joints. The self-healing adhesives exhibit recovery of both cohesion and adhesion properties with room temperature healing.

  20. Lap Shear and Impact Testing of Ochre and Beeswax in Experimental Middle Stone Age Compound Adhesives.

    Science.gov (United States)

    Kozowyk, P R B; Langejans, G H J; Poulis, J A

    2016-01-01

    The production of compound adhesives using disparate ingredients is seen as some of the best evidence of advanced cognition outside of the use of symbolism. Previous field and laboratory testing of adhesives has shown the complexities involved in creating an effective Middle Stone Age glue using Acacia gum. However, it is currently unclear how efficient different adhesive recipes are, how much specific ingredients influence their performance, and how difficult it may have been for those ingredients to be combined to maximum effect. We conducted a series of laboratory-based lap shear and impact tests, following modern adhesion testing standards, to determine the efficacy of compound adhesives, with particular regard to the ingredient ratios. We tested rosin (colophony) and gum adhesives, containing additives of beeswax and ochre in varying ratios. During both lap shear and impact tests compound rosin adhesives performed better than single component rosin adhesives, and pure acacia gum was the strongest. The large difference in performance between each base adhesive and the significant changes in performance that occur due to relatively small changes in ingredient ratios lend further support to the notion that high levels of skill and knowledge were required to consistently produce the most effective adhesives.

  1. Monitoring of fatigue damage in composite lap-joints using guided waves and FBG sensors

    Science.gov (United States)

    Karpenko, Oleksii; Khomenko, Anton; Koricho, Ermias; Haq, Mahmoodul; Udpa, Lalita

    2016-02-01

    Adhesive bonding is being increasingly employed in many applications as it offers possibility of light-weighting and efficient multi-material joining along with reduction in time and cost of manufacturing. However, failure initiation and progression in critical components like joints, specifically in fatigue loading is not well understood, which necessitates reliable NDE and SHM techniques to ensure structural integrity. In this work, concurrent guided wave (GW) and fiber Bragg grating (FBG) sensor measurements were used to monitor fatigue damage in adhesively bonded composite lap-joints. In the present set-up, one FBG sensor was strategically embedded in the adhesive bond-line of a lap-joint, while two other FBGs were bonded on the surface of the adherends. Full spectral responses of FBG sensors were collected and compared at specific intervals of fatigue loading. In parallel, guided waves were actuated and sensed using PZT wafers mounted on the composite adherends. Experimental results demonstrated that time-of-flight (ToF) of the fundamental modes transmitted through the bond-line and spectral response of FBG sensors were sensitive to fatigue loading and damage. Combination of guided wave and FBG measurements provided the desired redundancy and synergy in the data to evaluate the degradation in bond-line properties. Measurements taken in the presence of continuously applied load replicated the in-situ/service conditions. The approach shows promise in understanding the behavior of bonded joints subjected to complex loading.

  2. Investigation of corrosion behavior of Mg-steel laser-TIG hybrid lap joints

    Energy Technology Data Exchange (ETDEWEB)

    Liu Liming, E-mail: liulm@dlut.edu.cn [Key Laboratory of Liaoning Advanced Welding and Joining Technology, School of Materials Science and Engineering, Dalian University of Technology, Dalian 116024 (China); Xu Rongzheng [Key Laboratory of Liaoning Advanced Welding and Joining Technology, School of Materials Science and Engineering, Dalian University of Technology, Dalian 116024 (China)

    2012-01-15

    Highlights: Black-Right-Pointing-Pointer Galvanic corrosion increases the corrosion rate of the Mg-steel joint. Black-Right-Pointing-Pointer Fe splashes lower the corrosion resistance of the joint greatly. Black-Right-Pointing-Pointer The effect of grain refinement on the corrosion behavior of the joint is slight. Black-Right-Pointing-Pointer Ni or Cu interlayer could not improve the corrosion resistance of fusion zone. Black-Right-Pointing-Pointer The arc-sprayed coating could enhance the reliability of weld joint. - Abstract: The paper investigates the corrosion behavior of the lap joint of AZ31 magnesium alloy to Q235 steel with salt solution immersion testing and electrochemical testing. It is demonstrated that grain refinement resulting from the welding process has little effect on the corrosion behavior of the lap joint. However, the cathodic phases formed in the welding process and the galvanic corrosion between magnesium alloy and steel decrease the corrosion resistance of the joint greatly. Besides, neither Cu nor Ni, as filler material, could improve the corrosion resistance of the joint, but the arc-sprayed Al coating acting as a protective layer could.

  3. Lap shear strength and healing capability of self-healing adhesive containing epoxy/mercaptan microcapsules

    International Nuclear Information System (INIS)

    Ghazali, Habibah; Ye, Lin; Zhang, Ming-Qiu

    2016-01-01

    The aim of this work is to develop a self-healing polymeric adhesive formulation with epoxy/mercaptan microcapsules. Epoxy/mercaptan microcapsules were dispersed into a commercialize two-part epoxy adhesive for developing self-healing epoxy adhesive. The influence of different content of microcapsules on the shear strength and healing capability of epoxy adhesive were investigated using single-lap-joints with average thickness of adhesive layer of about 180 µm. This self-healing adhesive was used in bonding of 5000 series aluminum alloys adherents after mechanical and alkaline cleaning surface treatment. The adhesion strength was measured and presented as function of microcapsules loading. The results indicated that the virgin lap shear strength was increased by about 26% with addition of 3 wt% of self-healing microcapsules. 12% to 28% recovery of the shear strength is achieved after self-healing depending on the microcapsules content. Scanning electron microscopy was used to study fracture surface of the joints. The self-healing adhesives exhibit recovery of both cohesion and adhesion properties with room temperature healing.

  4. Investigation of corrosion behavior of Mg-steel laser-TIG hybrid lap joints

    International Nuclear Information System (INIS)

    Liu Liming; Xu Rongzheng

    2012-01-01

    Highlights: ► Galvanic corrosion increases the corrosion rate of the Mg-steel joint. ► Fe splashes lower the corrosion resistance of the joint greatly. ► The effect of grain refinement on the corrosion behavior of the joint is slight. ► Ni or Cu interlayer could not improve the corrosion resistance of fusion zone. ► The arc-sprayed coating could enhance the reliability of weld joint. - Abstract: The paper investigates the corrosion behavior of the lap joint of AZ31 magnesium alloy to Q235 steel with salt solution immersion testing and electrochemical testing. It is demonstrated that grain refinement resulting from the welding process has little effect on the corrosion behavior of the lap joint. However, the cathodic phases formed in the welding process and the galvanic corrosion between magnesium alloy and steel decrease the corrosion resistance of the joint greatly. Besides, neither Cu nor Ni, as filler material, could improve the corrosion resistance of the joint, but the arc-sprayed Al coating acting as a protective layer could.

  5. Joining aluminum to titanium alloy by friction stir lap welding with cutting pin

    International Nuclear Information System (INIS)

    Wei, Yanni; Li, Jinglong; Xiong, Jiangtao; Huang, Fu; Zhang, Fusheng; Raza, Syed Hamid

    2012-01-01

    Aluminum 1060 and titanium alloy Ti–6Al–4V plates were lap joined by friction stir welding. A cutting pin of rotary burr made of tungsten carbide was employed. The microstructures of the joining interface were observed by scanning electron microscopy. Joint strength was evaluated by a tensile shear test. During the welding process, the surface layer of the titanium plate was cut off by the pin, and intensively mixed with aluminum situated on the titanium plate. The microstructures analysis showed that a visible swirl-like mixed region existed at the interface. In this region, the Al metal, Ti metal and the mixed layer of them were all presented. The ultimate tensile shear strength of joint reached 100% of 1060Al that underwent thermal cycle provided by the shoulder. - Highlights: ► FSW with cutting pin was successfully employed to form Al/Ti lap joint. ► Swirl-like structures formed due to mechanical mixing were found at the interface. ► High-strength joints fractured at Al suffered thermal cycle were produced.

  6. Grey Water Reuse for Agricultural Purposes in the Jordan Valley: Household Survey Results in Deir Alla

    Directory of Open Access Journals (Sweden)

    Sharon B. Megdal

    2012-08-01

    Full Text Available Installation of decentralized grey water treatment systems in small rural communities contributes to a more sustainable water supply. In order to gauge community attitudes about collection and use of grey water, a door-to-door survey in the farming community of Deir Alla, Jordan was conducted by Royal Scientific Society interviewers. Outcomes of a detailed survey, designed specifically for this project, offer insights on people’s views on general water and wastewater issues, as well as their motivation, practices and concerns related to using grey water treatment for a portion of their household wastewater and reuse of the treated grey water for irrigation. A total of 47 respondents from different socio-economic background, aged over 18 years, from this community in the Jordan valley took part in the survey. The level of formal education of the respondents was low, and most of households’ incomes were below the poverty line in Jordan. Most of the respondents reported that the quality of water supplied by public network is acceptable, but the quantity is insufficient to meet their demand, with supplies being delivered to the household once a week. Respondents relied on the public water network as a first-most important resource (85.1%, and 57.4% of the respondent relied on private water tankers as a second-most important resource in addition to the public network. However, 6% of the respondents relied only on private water tankers with no access to the public network. Storage tanks are common practice in all the houses in order to store enough water for at least one week. The survey responses provide evidence that rural communities are willing to accept reuse of treated grey water for irrigation. Furthermore, some of people in the studied area are willing to learn more about grey water treatment and reuse in order to operate grey water systems for irrigation purposes. Water scarcity in this rural area of Jordan is the main determinant of

  7. PENINGKATAN KEMAMPUAN PEMECAHAN MASALAH MATEMATIKA SISWA MELALUI MODEL PEMBELAJARAN LAPS-HEURISTIC DIKELAS X SMAN 2 BATANG ANAI

    Directory of Open Access Journals (Sweden)

    Adri Nofrianto

    2017-01-01

    Full Text Available Penelitian ini bertujuan untuk mengetahui peningkatan kemampuan pemecahan masalah matematika siswa melalui model pembelajaran LAPS-Heuristic. Jenis penelitian ini yaitu penelitian deskriptif kualitatif. Subjek dalam penelitian ini dipilih dua siswa dari kelas penelitian yaitu kelas X SMAN 2 Batang Anai. Subjek yang dipilih dalam merupakan siswa yang memiliki kemampuan matematika tinggi. Data dikumpulkan melalui tes pemecahan masalah dan wawancara. Hal ini dilakukan sebelum dan sesudah penerapa model pembelajaran LAPS-Heuristic. Berdasarkan hasil deskripsi dan analisis data, dapat dilihat perkembangan kemampuan pemecahan masalah matematika siswa meningkat pada saat dilakukan tes akhir. Pada hasil penilaian berdasarkan rubrik pemecahan masalah matematika, diperoleh tingkat kategori sangat memuaskan dengan indikator pencapaian: memahami soal dengan benar, rencana strategi penyelesaian yang benar, mengarah pada jawaban yang benar dan adanya pengecekan kembali hasil perhitungan, sehingga dapat disimpulkan bahwa model pembelajaran LAPS-Heuristic berpengaruh terhadap kemampuan pemecahan masalah matematika siswa kelas X SMAN 2 Batag Anai. Kata kunci: kesulitan matematika, pemecahan masalah, LAPS-Heuristic This research aims to determine the increase in mathematics problem solving ability of students through learning model LAPS-Heuristic. Type of research is a qualitative descriptive study. The subjects in this study were selected two students from class research that is class X SMAN 2 Batang Anai. Subjects selected were the students who have high math skills. Data were collected through a problem-solving test and interview. This data collection was done before and after the implementation of learning model LAPS-Heuristic. Based on the description and analysis of the test, it can be seen that the development of mathematical problem solving ability of students increased at the time of the final test. The results of the assessment under the rubric of

  8. Multifrequency Eddy Current Inspection of Corrosion in Clad Aluminum Riveted Lap Joints and Its Effect on Fatigue Life

    Science.gov (United States)

    Okafor, A. C.; Natarajan, S.

    2007-03-01

    Aging aircraft are prone to corrosion damage and fatigue cracks in riveted lap joints of fuselage skin panels. This can cause catastrophic failure if not detected and repaired. Hence detection of corrosion damage and monitoring its effect on structural integrity are essential. This paper presents multifrequency eddy current (EC) inspection of corrosion damage and machined material loss defect in clad A1 2024-T3 riveted lap joints and its effect on fatigue life. Results of eddy current inspection, corrosion product removal and fatigue testing are presented.

  9. Multifrequency Eddy Current Inspection of Corrosion in Clad Aluminum Riveted Lap Joints and Its Effect on Fatigue Life

    International Nuclear Information System (INIS)

    Okafor, A. C.; Natarajan, S.

    2007-01-01

    Aging aircraft are prone to corrosion damage and fatigue cracks in riveted lap joints of fuselage skin panels. This can cause catastrophic failure if not detected and repaired. Hence detection of corrosion damage and monitoring its effect on structural integrity are essential. This paper presents multifrequency eddy current (EC) inspection of corrosion damage and machined material loss defect in clad A1 2024-T3 riveted lap joints and its effect on fatigue life. Results of eddy current inspection, corrosion product removal and fatigue testing are presented

  10. The LapG protein plays a role in Pseudomonas aeruginosa biofilm formation by controlling the presence of the CdrA adhesin on the cell surface

    DEFF Research Database (Denmark)

    Rybtke, Morten; Berthelsen, Jens; Yang, Liang

    2015-01-01

    Pseudomonas aeruginosa is a clinically relevant species involved in biofilm-based chronic infections. We provide evidence that the P. aeruginosa LapG protein functions as a periplasmic protease that can cleave the protein adhesin CdrA off the cell surface, and thereby plays a role in biofilm...... formation and biofilm dispersal. The P. aeruginosa LapG protein is shown to be a functional homolog of the Pseudomonas putida LapG protein which has previously been shown to function as a periplasmic protease that targets the surface adhesin LapA. Transposon mutagenesis and characterization of defined...... and whole-cell protein fractions showed that CdrA was retained in the whole-cell protein fraction when LapG was absent, whereas it was found in the culture supernatant when LapG was present. The finding that CdrA is a target of LapG in P. aeruginosa is surprising because CdrA has no homology to LapA....

  11. An evaluation of the lap-shear test for Sn-rich solder/Cu couples: Experiments and simulation

    Science.gov (United States)

    Chawla, N.; Shen, Y.-L.; Deng, X.; Ege, E. S.

    2004-12-01

    The lap-shear technique is commonly used to evaluate the shear, creep, and thermal fatigue behavior of solder joints. We have conducted a parametric experimental and modeling study, on the effect of testing and geometrical parameters on solder/copper joint response in lap-shear. It was shown that the farfield applied strain is quite different from the actual solder strain (measured optically). Subtraction of the deformation of the Cu substrate provides a reasonable approximation of the solder strain in the elastic regime, but not in the plastic regime. Solder joint thickness has a profound effect on joint response. The solder response moves progressively closer to “true” shear response with increasing joint thickness. Numerical modeling using finite-element analyses were performed to rationalize the experimental findings. The same lap-shear configuration was used in the simulation. The input response for solder was based on the experimental tensile test result on bulk specimens. The calculated shear response, using both the commonly adopted far-field measure and the actual shear strain in solder, was found to be consistent with the trends observed in the lap-shear experiments. The geometric features were further explored to provide physical insight into the problem. Deformation of the substrate was found to greatly influence the shear behavior of the solder.

  12. PENGEMBANGAN KARAKTER KEDISIPLINAN DAN KEMAMPUAN PEMECAHAN MASALAH MELALUI MODEL LAPS-HEURISTIK MATERI LINGKARAN KELAS-VIII

    Directory of Open Access Journals (Sweden)

    Sri Wahyuni

    2015-08-01

    Full Text Available Tujuan penelitian ini adalah untuk mengetahui (1 apakah pembelajaran dengan model pembelajaran LAPS-Heuristik pada materi lingkaran kelas-VIII dapat mengembangkan karakter kedisiplinan peserta didik, (2 apakah pembelajaran dengan model pembelajaran LAPS-Heuristik pada materi lingkaran kelas-VIII dapat meningkatkan kemampuan pemecahan masalah peserta didik, (3 apakah kemampuan pemecahan masalah matematika peserta didik yang diajar dengan model pembelajaran LAPS-Heuristik pada materi lingkaran kelas-VIII dapat mencapai kriteria ketuntasan minimal yang ditentukan. Desain penelitian ini adalah kualitatif deskriptif, artinya menggambarkan atau mendeskripsikan kejadian-kejadian yang menjadi pusat perhatian secara kualitatif dan berdasar data kualitatif. Penentuan sumber data dalam penelitian ini menggunakan teknik purposive sampling, yaitu dipilih dengan pertimbangan dan tujuan tertentu. Data diperoleh dengan observasi, wawancara, dan tes yang kemudian dianalisis menggunakan analisis kualitatif dan analisis gain untuk mengukur peningkatan. Analisis kualitatif menunjukkan karakter kedisiplinan dan kemampuan pemecahan masalah peserta didik meningkat, serta kemampuan pemecahan masalah peserta didik mencapai KKM melalui model pembelajaran LAPS-Heuristik.

  13. The Effect of Wetting Gravity Regime on Shear Strength of SAC and Sn-Pb Solder Lap Joints

    Science.gov (United States)

    Sona, Mrunali; Prabhu, K. Narayan

    2017-09-01

    The failure of solder joints due to imposed stresses in an electronic assembly is governed by shear bond strength. In the present study, the effect of wetting gravity regime on single-lap shear strength of Sn-0.3Ag-0.7Cu and Sn-2.5Ag-0.5Cu solder alloys reflowed between bare copper substrates as well as Ni-coated Cu substrates was investigated. Samples were reflowed for 10 s, T gz (time corresponding to the end of gravity regime) and 100 s individually and tested for single-lap shear strength. The single-lap shear test was also carried out on eutectic Sn-Pb/Cu- and Sn-Pb/Ni-coated Cu specimens to compare the shear strength values obtained with those of lead-free alloys. The eutectic Sn-Pb showed significantly higher ultimate shear strength on bare Cu substrates when compared to Sn-Ag-Cu alloys. However, SAC alloys reflowed on nickel-coated copper substrate exhibited higher shear strength when compared to eutectic Sn-Pb/Ni-coated Cu specimens. All the substrate/solder/substrate lap joint specimens that were reflowed for the time corresponding to the end of gravity regime exhibited maximum ultimate shear strength.

  14. Research on the design of surface acquisition system of active lap based on FPGA and FX2LP

    Science.gov (United States)

    Zhao, Hongshen; Li, Xiaojin; Fan, Bin; Zeng, Zhige

    2014-08-01

    In order to research the dynamic surface shape changes of active lap during the processing, this paper introduces a dynamic surface shape acquisition system of active lap using FPGA and USB communication. This system consists of high-precision micro-displacement sensor array, acquisition board, PC computer composition, and acquisition circuit board includes six sub-boards based on FPGA, a hub-board based on FPGA and USB communication. A sub-board is responsible for a number of independent channel sensors' data acquisition; hub-board is responsible for creating encoder simulation tools to active lap deformation control system with location information, sending synchronization information to latch the sensor data in all of the sub-boards for a time, while addressing the sub-boards to gather the sensor data in each sub-board one by one and transmitting all the sensor data together with location information via the USB chip FX2LP to the host computer. Experimental results show that the system is capable of fixing the location and speed of active lap, meanwhile the control of surface transforming and dynamic surface data acquisition at a certain location in the processing is implemented.

  15. Microstructures and mechanical properties of magnesium alloy and stainless steel weld-joint made by friction stir lap welding

    International Nuclear Information System (INIS)

    Wei, Yanni; Li, Jinglong; Xiong, Jiangtao; Huang, Fu; Zhang, Fusheng

    2012-01-01

    Highlights: → Friction stir lap welding technology with cutting pin was successfully employed to form lap joint of magnesium and steel. → The cutting pin made the lower steel participate in deformation and the interface was no longer flat. → A saw-toothed structure formed due to a mechanical mixing of the magnesium and steel was found at the interface. → A high-strength joint was produced which fractured in the magnesium side. -- Abstract: Friction stir lap welding was conducted on soft/hard metals. A welding tool was designed with a cutting pin of rotary burr made of tungsten carbide, which makes the stirring pin possible to penetrate and cut the surface layer of the hard metal. Magnesium alloy AZ31 and stainless steel SUS302 were chosen as soft/hard base metals. The structures of the joining interface were analyzed by scanning electron microscopy (SEM). The joining strength was evaluated by tensile shear test. The results showed that flower-like interfacial morphologies were presented with steel flashes and scraps, which formed bonding mechanisms of nail effect by long steel flashes, zipper effect by saw-tooth structure and metallurgical bonding. The shear strength of the lap joint falls around the shear strength of butt joint of friction stir welded magnesium alloy.

  16. Characterization of lap joints laser beam welding of thin AA 2024 sheets with Yb:YAG disk-laser

    Science.gov (United States)

    Caiazzo, Fabrizia; Alfieri, Vittorio; Cardaropoli, Francesco; Sergi, Vincenzo

    2012-06-01

    Lap joints obtained by overlapping two plates are widely diffused in aerospace industry. Nevertheless, because of natural aging, adhesively bonded and riveted aircraft lap joints may be affected by cracks from rivets, voids or corrosion. Friction stir welding has been proposed as a valid alternative, although large heat affected zones are produced both in the top and the bottom plate due to the pin diameter. Interest has therefore been shown in studying laser lap welding as the laser beam has been proved to be competitive since it allows to concentrate the thermal input and increases productivity and quality. Some challenges arise as a consequence of aluminum low absorptance and high thermal conductivity; furthermore, issues are due to metallurgical challenges such as both micro and macro porosity formation and softening in the fused zone. Welding of AA 2024 thin sheets in a lap joint configuration is discussed in this paper: tests are carried out using a recently developed Trumpf TruDisk 2002 Yb:YAG disk-laser with high beam quality which allows to produce beads with low plates distortion and better penetration. The influence of the processing parameters is discussed considering the fused zone extent and the bead shape. The porosity content as well as the morphological features of the beads have been examined.

  17. Double fillet lap of laser welding of thin sheet AZ31B Mg alloy

    Science.gov (United States)

    Ishak, Mahadzir; Salleh, M. N. M.

    2018-05-01

    In this paper, we describe the experimental laser welding of thin sheet AZ31B using double fillet lap joint method. Laser welding is capable of producing high quality weld seams especially for small weld bead on thin sheet product. In this experiment, both edges for upper and lower sheets were subjected to the laser beam from the pulse wave (PW) mode of fiber laser. Welded sample were tested their joint strength by tensile-shear strength method and the fracture loads were studied. Strength for all welded samples were investigated and the effect of laser parameters on the joint strength and appearances were studied. Pulsed energy (EP) from laser process give higher effect on joint strength compared to the welding speed (WS) and angle of irradiation (AOI). Highest joint strength was possessed by sample with high EP with the same value of WS and AOI. The strength was low due to the crack defect at the centre of weld region.

  18. Nano-modified adhesive by graphene: the single lap-joint case

    Energy Technology Data Exchange (ETDEWEB)

    Silva Neto, Almir; Cruz, Diego Thadeu Lopes da; Avila, Antonio Ferreira, E-mail: aavila@netuno.lcc.ufmg.b [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Dept. de Engenharia Mecanica

    2013-11-01

    This paper addresses the performance study on, low viscosity, nano-modified adhesives by graphene. For achieving this goal, single-lap joints following ASTM D 5868-01 were manufactured and tested. X-ray diffraction, scanning electron microscopy and nanoindentation were employed for graphene based nanostructures characterization. The increase on joint strength was around 57% when compared against the control group. Furthermore, all failures for the nano-modified adhesive were cohesive failure for the carbon fibre/epoxy composites indicating that the adhesive was tested. X-ray diffractions signatures indicate formation of nano-structures with 17-19 nm diameters. Moreover, nanoindentation tests revealed a homogeneous dispersion of graphene. (author)

  19. Swimming in a contained space: Understanding the experience of indoor lap swimmers.

    Science.gov (United States)

    Ward, Miranda

    2017-07-01

    Drawing on ethnographic work, this paper explores the convergence of bodies, materialities and practices found at the indoor swimming pool - a space that has not often been the subject of geographical study, in spite of the fact that swimming is one of the most popular forms of exercise in countries such as the UK. The paper focuses on the "contained" nature of the indoor pool environment, examining the distinct experience this can create for lap swimmers. This focus is placed in the context of a broader politics of exercise, with an emphasis on the popularity and potential benefits of swimming, as well as less encouraging facts about participation and facility provision, suggesting that in order to encourage further uptake of swimming and preservation of swimming facilities the voices and experiences of regular swimmers should be considered. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. FRACTURE MECHANICS APPROACH TO ESTIMATE FATIGUE LIVES OF WELDED LAP-SHEAR SPECIMENS

    Energy Technology Data Exchange (ETDEWEB)

    Lam, P.; Michigan, J.

    2014-04-25

    A full range of stress intensity factor solutions for a kinked crack is developed as a function of weld width and the sheet thickness. When used with the associated main crack solutions (global stress intensity factors) in terms of the applied load and specimen geometry, the fatigue lives can be estimated for the laser-welded lap-shear specimens. The estimations are in good agreement with the experimental data. A classical solution for an infinitesimal kink is also employed in the approach. However, the life predictions tend to overestimate the actual fatigue lives. The traditional life estimations with the structural stress along with the experimental stress-fatigue life data (S-N curve) are also provided. In this case, the estimations only agree with the experimental data under higher load conditions.

  1. Creep analysis of adhesively bonded single lap joint using finite element method

    International Nuclear Information System (INIS)

    Zehsaz, Mohammad; Vakilitahami, Tahami Farid; Saeimisadigh, Mohammad Ali

    2014-01-01

    Adhesive joints are being used widely in engineering industries due to the increasing demand for designing lightweight structures. Because of the physical properties of the most adhesives, they creep even at room temperature. Therefore, the creep behavior of a single lap adhesive joint is studied in this paper. For this purpose, using the experimental data, creep constitutive equations for the adhesive has been obtained. Then, these equations have been employed to investigate the creep behavior of the joint. The results show that due to the creep straining, the stresses in the joint corners, decrease. However, creep strain accumulates in these areas which this in turn may lead to separation of adhesive from adherent. In order to eliminate the effect of strain accumulation, two modifying methods have been proposed in this paper: increasing the layer thickness and using filleted joints.

  2. Detection of fastener loosening in simple lap joint based on ultrasonic wavefield imaging

    Science.gov (United States)

    Gooda Sahib, M. I.; Leong, S. J.; Chia, C. C.; Mustapha, F.

    2017-12-01

    Joints in aero-mechanical structures are critical elements that ensure the structural integrity but they are prone to damages. Inspection of such joints that have no prior baseline data is really challenging but it can be possibly done using the Ultrasonic Propagation Imager (UPI). The feasibility of applying UPI for detection of loosened fastener is investigated in this study. A simple lap joint specimen made by connecting two pieces of 2.5mm thick SAE304 stainless steel plates using five M6 screws and nuts has been used in this study. All fasteners are tightened to 10Nm but one of them is completely loosened to simulate the damage. The wavefield data is processed into ultrasonic wavefield propagation video and a series of spectral amplitude images. The spectral images showed noticeable amplitude difference at the loosened fastener, hence confirmed the feasibility of using UPI for structural joints inspection. A simple contrast maximization method is also introduced to improve the result.

  3. Environmental influence on the usage of adhesive single lap joints in nuclear industry applications

    International Nuclear Information System (INIS)

    Amorim, Felipe do C.; Reis, João M.L. dos; Souza, João F.B. de; Costa, Gilberto T. de P.; Moura, Jorge C. de; Universidade Federal Fluminense; Comissao Nacional de Energia Nuclear

    2017-01-01

    Despite of some polymeric compounds vulnerability to different types of radiation, high polymer, as epoxy adhesives, had prospered in the nuclear industry because their mechanical properties to high doses of ionizing radiation is maintained. Because of this, epoxy adhesives are widely used in nuclear applications: nuclear power plants, aerospace components, radioactive sealed sources to medicine, radioactive waste immobilization. In the present work, the performance of a diglycidyl ether of bisphenol ether A (DGEBA) was analyzed. Tensile tests of adhesive single lap joints bonded with epoxy were performed. The environmental effect of ultraviolet (UV) exposure was observed in the mechanical reaction of PolyAnchor 4100 HT. In particular, maximum load decreases slightly in aggressive environment. It is possible to conclude the material is proper to use in internal and external areas, mainly due to the easy application when compared to welded joints with similar strength. The easy application reduces the workers exposure time to ionizing radiation. (author)

  4. Environmental influence on the usage of adhesive single lap joints in nuclear industry applications

    Energy Technology Data Exchange (ETDEWEB)

    Amorim, Felipe do C.; Reis, João M.L. dos; Souza, João F.B. de; Costa, Gilberto T. de P.; Moura, Jorge C. de, E-mail: felipe.amorim@cefet-rj.br, E-mail: jreis@id.uff.br, E-mail: joaofellipe@id.uff.br, E-mail: gilberto.costa@cnen.gov.br, E-mail: jcmoura@cnen.gov.br [Centro Federal de Educação Tecnológica Celso Suckow da Fonseca (CEFET-RJ), Itaguai, RJ (Brazil). Departamento de Engenharia Mecanica; Universidade Federal Fluminense (UFF), Niteroi, RJ (Brazil). Laboratorio de Mecania Teorica e Aplicada; Comissao Nacional de Energia Nuclear (CNEN), Rio de Janeiro, RJ (Brazil). Divisão de Controle de Rejeitos e Transporte de Materiais Radioativos

    2017-07-01

    Despite of some polymeric compounds vulnerability to different types of radiation, high polymer, as epoxy adhesives, had prospered in the nuclear industry because their mechanical properties to high doses of ionizing radiation is maintained. Because of this, epoxy adhesives are widely used in nuclear applications: nuclear power plants, aerospace components, radioactive sealed sources to medicine, radioactive waste immobilization. In the present work, the performance of a diglycidyl ether of bisphenol ether A (DGEBA) was analyzed. Tensile tests of adhesive single lap joints bonded with epoxy were performed. The environmental effect of ultraviolet (UV) exposure was observed in the mechanical reaction of PolyAnchor 4100 HT. In particular, maximum load decreases slightly in aggressive environment. It is possible to conclude the material is proper to use in internal and external areas, mainly due to the easy application when compared to welded joints with similar strength. The easy application reduces the workers exposure time to ionizing radiation. (author)

  5. Degradation of Epoxy-Steel Single Lap Joints Immersed in Water

    DEFF Research Database (Denmark)

    Goglio, L; Rezaei, Mohsen

    2015-01-01

    Exposure to environmental factors, especially moisture, is recognized as the major cause of degradation of adhesive joints. In this work, complementing a previous study on exposure to moisture, single lap joints were subjected to immersion in water, up to five weeks, at room temperature and 50 °C....... The material of the adherends was mild steel, and the adhesive was a bi-component epoxy. The specimens were fabricated using the open-face technique. Mechanical testing at the end of the relevant period of immersion showed an initial loss of ultimate load, after one week at 50 °C or two at room temperature......; then, the strength remained practically constant over the remaining time. The loss was more accentuated after immersion at 50 °C, about 70%, than at room temperature, about 30%. Also a reduction in stiffness of the joints was measured, again dramatic (about 70%) after immersion at 50 °C, moderate...

  6. Efficacia e indicazioni del counseling e delle strategie educative nel miglioramento della compliance alla ventilazione a pressione positiva continua – CPAP

    Directory of Open Access Journals (Sweden)

    Elena Peila

    2017-07-01

    Conclusioni: Le strategie educative sono tecniche efficaci per migliorare l'adrenza alla CPAP anche in popolazioni che abitualmente presentano bassa compliance come i pazienti senza beneficio soggettivo dalla terapia con CPAP o pazienti con comorbilità psichiatrica o cognitiva. Tuttavia sono raccomandati interventi educativi brevi.

  7. Risk from exposure to natural and artificial ultraviolet radiation; Il rischio di esposizione alla radiazione ultravioletta naturale e artificiale

    Energy Technology Data Exchange (ETDEWEB)

    Matzeu, M. [Istituto Superiore di Sanita`, Rome (Italy). Lab. di Fisica

    1998-12-31

    The association between exposure to ultraviolet (UV) and damage to the skin and eyes is today generally accepted. Exposure to UV radiation may occur in several ways. Apart from the sun, there is a wide range of artificial sources used in different fields of industry, research and medicine, the exposure to which adds to the total exposure of an individual during his life-span. The potential effects of ozone layer depletion on the increase of the solar UV radiation at earth`s surface, and therefor on human health, have recently been emphasized. Moreover, great attention has been devoted to the often uncontrolled use of UV lamps for tanning. This report shows the basis on which short and long term UV risk is assessed, and indicates some parameters necessary to its evaluation. The UV effects, both at molecular and cellular levels and on humans, are described together with their respective action spectra. The most common UV sources are then analyzed and their use in different fields is shown. Finally, some methods in dosimetry, which are useful for the correct measurement of exposure values, are described. [Italiano] E` oggi generalmente accettata l`assciazione tra l`esposizione alla radiazione UV e alcuni danni alla pelle e agli occhi (carcinomi e cataratta). Le occasioni di esposizione sono molteplici; oltre al sole, anche una grande varieta` di sorgenti artificiali impiegate per scopi diversi nell`industria, nella ricerca e in medicina danno un contributo, non sempre valutabile, all`esposizione totale di un individuo nell`arco della sua vita. Recentemente e` stato posto l`accento sulle possibili conseguenze della riduzione dello stato di ozono stratosferico sull`aumento della frazione di UV solare al suolo e quindi sulla salute umana; particolare attenzione ha inoltre suscitato l`uso, spesso incontrollato, delle lampade UV per scopi estetici. Sono illustrate le basi sulle quali viene riconosciuto il rischio a breve e a lungo termine e sono definiti i parametri

  8. Risk from exposure to natural and artificial ultraviolet radiation; Il rischio di esposizione alla radiazione ultravioletta naturale e artificiale

    Energy Technology Data Exchange (ETDEWEB)

    Matzeu, M [Istituto Superiore di Sanita` , Rome (Italy). Lab. di Fisica

    1999-12-31

    The association between exposure to ultraviolet (UV) and damage to the skin and eyes is today generally accepted. Exposure to UV radiation may occur in several ways. Apart from the sun, there is a wide range of artificial sources used in different fields of industry, research and medicine, the exposure to which adds to the total exposure of an individual during his life-span. The potential effects of ozone layer depletion on the increase of the solar UV radiation at earth`s surface, and therefor on human health, have recently been emphasized. Moreover, great attention has been devoted to the often uncontrolled use of UV lamps for tanning. This report shows the basis on which short and long term UV risk is assessed, and indicates some parameters necessary to its evaluation. The UV effects, both at molecular and cellular levels and on humans, are described together with their respective action spectra. The most common UV sources are then analyzed and their use in different fields is shown. Finally, some methods in dosimetry, which are useful for the correct measurement of exposure values, are described. [Italiano] E` oggi generalmente accettata l`assciazione tra l`esposizione alla radiazione UV e alcuni danni alla pelle e agli occhi (carcinomi e cataratta). Le occasioni di esposizione sono molteplici; oltre al sole, anche una grande varieta` di sorgenti artificiali impiegate per scopi diversi nell`industria, nella ricerca e in medicina danno un contributo, non sempre valutabile, all`esposizione totale di un individuo nell`arco della sua vita. Recentemente e` stato posto l`accento sulle possibili conseguenze della riduzione dello stato di ozono stratosferico sull`aumento della frazione di UV solare al suolo e quindi sulla salute umana; particolare attenzione ha inoltre suscitato l`uso, spesso incontrollato, delle lampade UV per scopi estetici. Sono illustrate le basi sulle quali viene riconosciuto il rischio a breve e a lungo termine e sono definiti i parametri

  9. Lipid accumulation product (LAP) as a criterion for the identification of the healthy obesity phenotype in postmenopausal women.

    Science.gov (United States)

    Lwow, Felicja; Jedrzejuk, Diana; Milewicz, Andrzej; Szmigiero, Leszek

    2016-09-01

    Obesity and its complications constitute a major health problem in postmenopausal women. The identification of the obesity phenotype, especially that of metabolically healthy obese (MHO) patients, is a necessary part of obesity treatment protocols. There are several methods to define MHO, but unfortunately, all of them are arbitrary and inconsistent. The aim of this work was to determine whether lipid accumulation product (LAP) could be used as a marker of the MHO phenotype in postmenopausal women. A sample of 345 Polish postmenopausal women aged 50-60years old participated in the study. Participants were classified as obese when their BMI was >27. Receiver operating characteristic curve analysis was performed to estimate the best cutoff for the LAP index value to identify postmenopausal women without metabolic syndrome components. We found that the best cutoff value was LAP ≤29.9, and this value was used to define MHO individuals. With this definition, the identification of MHO individuals could be made when both of the following criteria were met: LAP index ≤29.9 and no arterial hypertension (SBPwomen identified according to the above definition, were compared with those of MHO women identified by two other methods in the literature. These methods and our definition identified similar proportions of MHO women ranging from 11.6% to 16.9%. We found that MHO women identified by all of the definitions used in this study possessed a similar metabolic status, and they did not differ in anthropometric indices or body fat distribution measurements. We concluded that the combination of LAP estimation and arterial blood pressure measurement appear to constitute a useful method for identifying the MHO phenotype in postmenopausal women. Copyright © 2016 Elsevier Inc. All rights reserved.

  10. The Balance of Th1/Th2 and LAP+Tregs/Th17 Cells Is Crucial for Graft Survival in Allogeneic Corneal Transplantation

    Directory of Open Access Journals (Sweden)

    Shang Li

    2018-01-01

    Full Text Available Purpose. CD4+LAP+ T cells are newly discovered regulatory T cells (Tregs. The aim of this study is to investigate the balance of Th1/Th2 and LAP+Tregs/Th17 in mice after allogeneic corneal transplantation. Methods. A total of 65 mice received orthotopic penetrating transplantation. According to the survival scores of the grafts, the mice were divided into the rejection group and the survival group 3 weeks after transplantation. Th1, Th2, Th17, and regulatory T cells in the ipsilateral drainage lymph nodes and spleens were measured with flow cytometry. The related cytokines in aqueous humor were also analyzed. Results. The frequencies of Foxp3+Tregs, GARP+Tregs, and LAP+Tregs in the survival group were significantly higher than those in the rejection group. And the expression trend of CD4+LAP+ T cells and CD4+GARP+ T cells was consistent. The level of IFN-γ, TNF, IL-6, and IL-17A markedly increased in aqueous humor during corneal allograft rejection. The ratio of Th1/Th2 and Th17/LAP+Tregs significantly increased in the rejection group at the 3rd week after corneal transplantation. Conclusion. LAP+Tregs might be regarded as substitute for Foxp3+Tregs. The balance of Th1/Th2 and LAP+Tregs/Th17 is crucial for corneal allograft survival.

  11. L'evoluzione della fisica sviluppo delle idee dai concetti iniziali alla relatività e ai quanti

    CERN Document Server

    Einstein, Albert

    1965-01-01

    Pubblicato in inglese alla vigilia della Seconda guerra mondiale e subito proposto in traduzione, L’evoluzione della fisica dovette aspettare la fine del conflitto per vedere la sua pubblicazione in Italia. Da allora (1948) questo testo non ha più smesso di rappresentare un punto di riferimento obbligato per il concetto stesso di divulgazione scientifica e per la fisica in particolare. Scritto dai protagonisti assoluti della rivoluzione della fisica relativistica e quantistica, ma destinato a un pubblico di non specialisti, il libro che avete tra le mani è il testo fondativo della moderna divulgazione delle idee, la pietra di paragone di ogni altro libro di fisica, che permette di intuire la straordinaria importanza e il valore rivoluzionario della svolta della fisica del Novecento.

  12. Induction of polyploidy by nuclear fusion mechanism upon decreased expression of the nuclear envelope protein LAP2β in the human osteosarcoma cell line U2OS.

    Science.gov (United States)

    Ben-Shoshan, Shirley Oren; Simon, Amos J; Jacob-Hirsch, Jasmine; Shaklai, Sigal; Paz-Yaacov, Nurit; Amariglio, Ninette; Rechavi, Gideon; Trakhtenbrot, Luba

    2014-01-28

    Polyploidy has been recognized for many years as an important hallmark of cancer cells. Polyploid cells can arise through cell fusion, endoreplication and abortive cell cycle. The inner nuclear membrane protein LAP2β plays key roles in nuclear envelope breakdown and reassembly during mitosis, initiation of replication and transcriptional repression. Here we studied the function of LAP2β in the maintenance of cell ploidy state, a role which has not yet been assigned to this protein. By knocking down the expression of LAP2β, using both viral and non-viral RNAi approaches in osteosarcoma derived U2OS cells, we detected enlarged nuclear size, nearly doubling of DNA content and chromosomal duplications, as analyzed by fluorescent in situ hybridization and spectral karyotyping methodologies. Spectral karyotyping analyses revealed that near-hexaploid karyotypes of LAP2β knocked down cells consisted of not only seven duplicated chromosomal markers, as could be anticipated by genome duplication mechanism, but also of four single chromosomal markers. Furthermore, spectral karyotyping analysis revealed that both of two near-triploid U2OS sub-clones contained the seven markers that were duplicated in LAP2β knocked down cells, whereas the four single chromosomal markers were detected only in one of them. Gene expression profiling of LAP2β knocked down cells revealed that up to a third of the genes exhibiting significant changes in their expression are involved in cancer progression. Our results suggest that nuclear fusion mechanism underlies the polyploidization induction upon LAP2β reduced expression. Our study implies on a novel role of LAP2β in the maintenance of cell ploidy status. LAP2β depleted U2OS cells can serve as a model to investigate polyploidy and aneuploidy formation by nuclear fusion mechanism and its involvement in cancerogenesis.

  13. German refrigeration sytems for Hong Kong Airport Chek Lap Kok and for Bangkok. Prause and Partner construct systems for Asia; Deutsche Kaeltetechnik fuer Hong Kongs Airport Chek Lap Kok, aber auch fuer Bangkok. Prause und Partner baut taifunsicher

    Energy Technology Data Exchange (ETDEWEB)

    Weissenborn, P.

    1998-09-01

    Hong Kong`s new airport Chek Lap Kok was commissioned on 6 July 1998 and is to become a turntable of air traffic in the Asian region. Prause and Partner, Goslar, will provide catering refrigeration systems for the airport. (orig.) [Deutsch] Hong Kongs neuer Airport Chek Lap Kok wird sich nach seiner Inbetriebnahme am 6. Juli 1998 zu einer der wichtigsten Drehscheiben im Luftverkehr Asiens entwickeln. Millionen von Fluggaesten werden dann taeglich mit Bordspeisen verpflegt werden muessen, bei deren Zubereitung und Konservierung die Kaeltetechnik eine bedeutende Funktion einnimmt. Deutsches Ingenieurwesen und solide deutsche Handwerkstechnik tragen dazu bei, dass `Catering-Refrigeration made by Prause and Partner`, Goslar, auch die Airline-Logistik der LSG Hong Kong zuverlaessig stuetzt. (orig./MSK)

  14. Rationale and Design of the Reduce Elevated Left Atrial Pressure in Patients With Heart Failure (Reduce LAP-HF) Trial

    DEFF Research Database (Denmark)

    Hasenfuss, Gerd; Gustafsson, Finn; Kaye, David

    2015-01-01

    OBJECTIVE: Heart failure with preserved ejection fraction (HFpEF) is characterized by elevated left atrial pressure during rest and/or exercise. The Reduce LAP-HF (Reduce Elevated Left Atrial Pressure in Patients With Heart Failure) trial will evaluate the safety and performance of the Interatrial...... Shunt Device (IASD) System II, designed to directly reduce elevated left atrial pressure, in patients with HFpEF. METHODS: The Reduce LAP-HF Trial is a prospective, nonrandomized, open-label trial to evaluate a novel device that creates a small permanent shunt at the level of the atria. A minimum of 60...... patients with ejection fraction ≥40% and New York Heart Association functional class III or IV heart failure with a pulmonary capillary wedge pressure (PCWP) ≥15 mm Hg at rest or ≥25 mm Hg during supine bike exercise will be implanted with an IASD System II, and followed for 6 months to assess the primary...

  15. Lamb wave-based damage quantification and probability of detection modeling for fatigue life assessment of riveted lap joint

    Science.gov (United States)

    He, Jingjing; Wang, Dengjiang; Zhang, Weifang

    2015-03-01

    This study presents an experimental and modeling study for damage detection and quantification in riveted lap joints. Embedded lead zirconate titanate piezoelectric (PZT) ceramic wafer-type sensors are employed to perform in-situ non-destructive testing during fatigue cyclical loading. A multi-feature integration method is developed to quantify the crack size using signal features of correlation coefficient, amplitude change, and phase change. In addition, probability of detection (POD) model is constructed to quantify the reliability of the developed sizing method. Using the developed crack size quantification method and the resulting POD curve, probabilistic fatigue life prediction can be performed to provide comprehensive information for decision-making. The effectiveness of the overall methodology is demonstrated and validated using several aircraft lap joint specimens from different manufactures and under different loading conditions.

  16. A new and specific non-NMDA receptor antagonist, FG 9065, blocks L-AP4-evoked depolarization in rat cerebral cortex.

    Science.gov (United States)

    Sheardown, M J

    1988-04-13

    L(+)-AP4 (2-amino-4-phosphonobutyrate) depolarized slices of rat cerebral cortex, when applied following a 2 min priming application of quisqualate. This response diminishes with time and is not seen after NMDA application. A new selective non-N-methyl-D-aspartate (NMDA) antagonist, 6-cyano-7-nitro-2,3-dihydroxyquinoxaline (FG 9065), inhibits the L(+)-AP4 depolarization. It is argued that the response is mediated indirectly by postsynaptic quisqualate receptors.

  17. Helios, and not FoxP3, is the marker of activated Tregs expressing GARP/LAP.

    Science.gov (United States)

    Elkord, Eyad; Abd Al Samid, May; Chaudhary, Belal

    2015-08-21

    Regulatory T cells (Tregs) are key players of immune regulation/dysregulation both in physiological and pathophysiological settings. Despite significant advances in understanding Treg function, there is still a pressing need to define reliable and specific markers that can distinguish different Treg subpopulations. Herein we show for the first time that markers of activated Tregs [latency associated peptide (LAP) and glycoprotein A repetitions predominant (GARP, or LRRC32)] are expressed on CD4+FoxP3- T cells expressing Helios (FoxP3-Helios+) in the steady state. Following TCR activation, GARP/LAP are up-regulated on CD4+Helios+ T cells regardless of FoxP3 expression (FoxP3+/-Helios+). We show that CD4+GARP+/-LAP+ Tregs make IL-10 immunosuppressive cytokine but not IFN-γ effector cytokine. Further characterization of FoxP3/Helios subpopulations showed that FoxP3+Helios+ Tregs proliferate in vitro significantly less than FoxP3+Helios- Tregs upon TCR stimulation. Unlike FoxP3+Helios- Tregs, FoxP3+Helios+ Tregs secrete IL-10 but not IFN-γ or IL-2, confirming they are bona fide Tregs with immunosuppressive characteristics. Taken together, Helios, and not FoxP3, is the marker of activated Tregs expressing GARP/LAP, and FoxP3+Helios+ Tregs have more suppressive characteristics, compared with FoxP3+Helios- Tregs. Our work implies that therapeutic modalities for treating autoimmune and inflammatory diseases, allergies and graft rejection should be designed to induce and/or expand FoxP3+Helios+ Tregs, while therapies against cancers or infectious diseases should avoid such expansion/induction.

  18. Validation of a novel basic virtual reality simulator, the LAP-X, for training basic laparoscopic skills.

    Science.gov (United States)

    Kawaguchi, Koji; Egi, Hiroyuki; Hattori, Minoru; Sawada, Hiroyuki; Suzuki, Takahisa; Ohdan, Hideki

    2014-10-01

    Virtual reality surgical simulators are becoming popular as a means of providing trainees with an opportunity to practice laparoscopic skills. The Lap-X (Epona Medical, Rotterdam, the Netherlands) is a novel VR simulator for training basic skills in laparoscopic surgery. The objective of this study was to validate the LAP-X laparoscopic virtual reality simulator by assessing the face and construct validity in order to determine whether the simulator is adequate for basic skills training. The face and content validity were evaluated using a structured questionnaire. To assess the construct validity, the participants, nine expert surgeons (median age: 40 (32-45)) (>100 laparoscopic procedures) and 11 novices performed three basic laparoscopic tasks using the Lap-X. The participants reported a high level of content validity. No significant differences were found between the expert surgeons and the novices (Ps > 0.246). The performance of the expert surgeons on the three tasks was significantly better than that of the novices in all parameters (Ps training device.

  19. Endovascular management of lap belt-related abdominal aortic injury in a 9-year-old child.

    Science.gov (United States)

    Papazoglou, Konstantinos O; Karkos, Christos D; Kalogirou, Thomas E; Giagtzidis, Ioakeim T

    2015-02-01

    Blunt abdominal aortic trauma is a rare occurrence in children with only a few patients having been reported in the literature. Most such cases have been described in the context of lap belt injuries. We report a 9-year-old boy who suffered lap belt trauma to the abdomen during a high-speed road traffic accident resulting to the well-recognized pattern of blunt abdominal injury, that is, the triad of intestinal perforation, fractures of the lumbar spine, and abdominal aortic injury. The latter presented with lower limb ischemia due to dissection of the infrarenal aorta and right common iliac artery. Revascularization was achieved by endovascular means using 2 self-expanding stents in the infrarenal aorta and the right common iliac artery. This case is one of the few reports of lap belt-related acute traumatic abdominal aortic dissection in a young child and highlights the feasibility of endovascular management in the pediatric population. Copyright © 2015 Elsevier Inc. All rights reserved.

  20. Hsp65-producing Lactococcus lactis prevents experimental autoimmune encephalomyelitis in mice by inducing CD4+LAP+ regulatory T cells

    Science.gov (United States)

    Rezende, Rafael M.; Oliveira, Rafael P.; Medeiros, Samara R.; Gomes-Santos, Ana C.; Alves, Andrea C.; Loli, Flávia G.; Guimarães, Mauro A.F.; Amaral, Sylvia S.; da Cunha, André P.; Weiner, Howard L.; Azevedo, Vasco; Miyoshi, Anderson; Faria, Ana M.C.

    2013-01-01

    Heat shock proteins (Hsps) participate in the cellular response to stress and they are hiperexpressed in inflammatory conditions. They are also known to play a major role in immune modulation, controlling, for instance, autoimmune responses. In this study, we showed that oral administration of a recombinant Lactococcus lactis strain that produces and releases LPS-free Hsp65 prevented the development of experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice. This was confirmed by the reduced inflammatory cell infiltrate and absence of injury signs in the spinal cord. The effect was associated with reduced IL-17 and increased IL-10 production in mesenteric lymph node and spleen cell cultures. Hsp65-producing-L. lactis-fed mice had a remarkable increase in the number of natural and inducible CD4+Foxp3+ regulatory T (Treg) cells and CD4+LAP+ (Latency-associated peptide) Tregs - which express the membrane-bound TGF-β - in spleen, inguinal and mesenteric lymph nodes as well as in spinal cord. Moreover, many Tregs co-expressed Foxp3 and LAP. In vivo depletion of LAP+ cells abrogated the effect of Hsp65-producing L. lactis in EAE prevention and worsened disease in medium-fed mice. Thus, Hsp65-L.lactis seems to boost this critical regulatory circuit involved in controlling EAE development in mice. PMID:22939403

  1. Multi-Track Friction Stir Lap Welding of 2024 Aluminum Alloy: Processing, Microstructure and Mechanical Properties

    Directory of Open Access Journals (Sweden)

    Shengke Zou

    2016-12-01

    Full Text Available Friction stir lap welding (FSLW raises the possibility of fabricating high-performance aluminum components at low cost and high efficiency. In this study, we mainly applied FSLW to fabricate multi-track 2024 aluminum alloy without using tool tilt angle, which is important for obtaining defect-free joint but significantly increases equipment cost. Firstly, systematic single-track FSLW experiments were conducted to attain appropriate processing parameters, and we found that defect-free single-track could also be obtained by the application of two-pass processing at a rotation speed of 1000 rpm and a traverse speed of 300 mm/min. Then, multi-track FSLW experiments were conducted and full density multi-track samples were fabricated at an overlapping rate of 20%. Finally, the microstructure and mechanical properties of the full density multi-track samples were investigated. The results indicated that ultrafine equiaxed grains with the grain diameter about 9.4 μm could be obtained in FSLW samples due to the dynamic recrystallization during FSLW, which leads to a yield strength of 117.2 MPa (17.55% higher than the rolled 2024-O alloy substrate and an elongation rate of 31.05% (113.84% higher than the substrate.

  2. Nondestructive Evaluation of Friction Stir-Welded Aluminum Alloy to Coated Steel Sheet Lap Joint

    Science.gov (United States)

    Das, H.; Kumar, A.; Rajkumar, K. V.; Saravanan, T.; Jayakumar, T.; Pal, Tapan Kumar

    2015-11-01

    Dissimilar lap joints of aluminum sheet (AA 6061) of 2 mm thickness and zinc-coated steel sheet of 1 mm thickness were produced by friction stir welding with different combinations of rotational speed and travel speed. Ultrasonic C- and B-scanning, and radiography have been used in a complementary manner for detection of volumetric (cavity and flash) and planar (de bond) defects as the defects are in micron level. Advanced ultrasonic C-scanning did not provide any idea about the defects, whereas B-scanning cross-sectional image showed an exclusive overview of the micron-level defects. A digital x-ray radiography methodology is proposed for quality assessment of the dissimilar welds which provide three-fold increase in signal-to-noise ratio with improved defect detection sensitivity. The present study clearly shows that the weld tool rotational speed and travel speed have a decisive role on the quality of the joints obtained by the friction stir welding process. The suitability of the proposed NDE techniques to evaluate the joint integrity of dissimilar FSW joints is thus established.

  3. [Endo-Lap method in the management of biliary lithiasis (gallbladder and common bile duct)].

    Science.gov (United States)

    Filip, V; Georgescu, St; Stanciu, C; Bălan, Gh; Târcoveanu, E; Neacşu, C N; Cîrdei, C; Drug, V L

    2004-01-01

    To present the results of the biliary endoscopic approach (ERCP) followed by laparoscopic cholecystectomy (LC) in the management of biliary lithiasis (gallbladder and common bile duct--CBD). From 1997 to March 2003 37 patients with biliary lithiasis were treated by endoscopic sphincterotomy (ES) with stone extraction, followed after 24-48 hours by LC. The indications for ERCP were presence of an obstructive jaundice (n=32) and a dilated CBD at the ultrasound examination (n=5). Selective biliary cannulation was obtained in 35 (94.6%) cases, in all of them with successful papillotomy. Stones were found in all patients. CBD clearances for calculi (from 1 to 8) was obtained in 33 of 35 patients (94.3%), the rest of 2 being managed by open laparotomy. Antibiotics were administrated in all patients. Laparoscopic cholecystectomy was performed after 24-48 hours, with one conversion (3%). Postoperative morbidity was 12.1%: 2 transitory pancreatic reactions and 2 wound infections. Endo-Lap method is a useful management alternative for combined gallbladder and CBD lithiasis. It has all the advantages of the two mini-invasive procedures (fast recovery, short hospitalization, low costs) and a less postoperative morbidity in patients with high risk.

  4. Strength and Failure Mechanism of Composite-Steel Adhesive Bond Single Lap Joints

    Directory of Open Access Journals (Sweden)

    Kai Wei

    2018-01-01

    Full Text Available Carbon fiber-reinforced plastics- (CFRP- steel single lap joints with regard to tensile loading with two levels of adhesives and four levels of overlap lengths were experimentally analyzed and numerically simulated. Both joint strength and failure mechanism were found to be highly dependent on adhesive type and overlap length. Joints with 7779 structural adhesive were more ductile and produced about 2-3 kN higher failure load than MA830 structural adhesive. Failure load with the two adhesives increased about 147 N and 176 N, respectively, with increasing 1 mm of the overlap length. Cohesion failure was observed in both types of adhesive joints. As the overlap length increased, interface failure appeared solely on the edge of the overlap in 7779 adhesive joints. Finite element analysis (FEA results revealed that peel and shear stress distributions were nonuniform, which were less severe as overlap length increased. Severe stress concentration was observed on the overlap edge, and shear failure of the adhesive was the main reason for the adhesive failure.

  5. Experimental characterization and numerical simulation of riveted lap-shear joints using Rivet Element

    Science.gov (United States)

    Vivio, Francesco; Fanelli, Pierluigi; Ferracci, Michele

    2018-03-01

    In aeronautical and automotive industries the use of rivets for applications requiring several joining points is now very common. In spite of a very simple shape, a riveted junction has many contact surfaces and stress concentrations that make the local stiffness very difficult to be calculated. To overcome this difficulty, commonly finite element models with very dense meshes are performed for single joint analysis because the accuracy is crucial for a correct structural analysis. Anyhow, when several riveted joints are present, the simulation becomes computationally too heavy and usually significant restrictions to joint modelling are introduced, sacrificing the accuracy of local stiffness evaluation. In this paper, we tested the accuracy of a rivet finite element presented in previous works by the authors. The structural behaviour of a lap joint specimen with a rivet joining is simulated numerically and compared to experimental measurements. The Rivet Element, based on a closed-form solution of a reference theoretical model of the rivet joint, simulates local and overall stiffness of the junction combining high accuracy with low degrees of freedom contribution. In this paper the Rivet Element performances are compared to that of a FE non-linear model of the rivet, built with solid elements and dense mesh, and to experimental data. The promising results reported allow to consider the Rivet Element able to simulate, with a great accuracy, actual structures with several rivet connections.

  6. Effect of friction stir lap welding conditions on joint strength of aluminium alloy 6060

    International Nuclear Information System (INIS)

    Yazdanian, S; Chen, Z W

    2009-01-01

    Strength of lap joints made by friction stir welding (FSW) depends strongly on how material flows forming the weld nugget zone during FSW and also on how the joint is loaded during testing. Understanding of this processing-property relationship is currently inadequate. In this study, the effects of pin length, welding speed and rotation rate on weld strength using aluminium alloy 6060 were investigated. It has been found that the pin length needed to be slightly greater than the thickness of the sheet for an adequate joint to be established. However, further increase in pin length did not benefit the joint strength. The major factor affecting joint strength has been found to be the rotation speed. An increase in rotation speed resulted in lowering the joint strength. Various modes of fracture have been observed and these modes relate to the degree of hooking and softening. Explanation of how the speed values relate to heat input and material flow and then to the joint strength is given.

  7. Numerical analysis of weld pool for galvanized steel with lap joint in GTAW

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Hunchul; Park, Kyungbae; Kim, Yougjun; Cho, Jungho [Chungbuk National University, Cheongju (Korea, Republic of); Kim, Dong-Yoon; Kang, Moon-Jin [Korea Institute of Industrial Technology, Incheon (Korea, Republic of)

    2017-06-15

    Galvanized steel is widely used and its demand is growing in automotive industry due to high quality requirement for corrosion resistance. Although there are a lot of demands on using galvanized steel as automotive parts especially for outer body, it has a grave flaw in its welding process. The difficulty is low weldability due to various defects such as porosities and blow holes in weldment, which occurred during welding. A solution to prevent these defects is using hybrid welding process, with two more welding processes. One of the hybrid solutions is using Gas tungsten arc welding (GTAW) as leading position in order to remove the zinc (Zn) coating on the surface before the followed practical fusion welding process. In this research, a numerical analysis model which can predict the eliminated Zn coated layers and the area of Fusion zone (FZ). Developed numerical analysis model was validated through comparing experiment to simulation. Basically, arc heat flux, arc pressure, electromagnetic force and Marangoni flow were employed as the boundary conditions and body force terms. Governing equations such as the continuity, momentum, Volume of fluid (VOF) and energy equations were adopted as usual. In addition to previous model, concentrated arc heat flux and contact thermal conductance models are newly suggested and showed successful result. They are adopted to realize edge concentrated arc and interfacial thermal conductance in lap joint fillet arc welding. Developed numerical analysis model successfully simulated the weld pool and temperature profile therefore the predicted Zn removed area considerably coincided with experimental result.

  8. Numerical analysis of weld pool for galvanized steel with lap joint in GTAW

    International Nuclear Information System (INIS)

    Jeong, Hunchul; Park, Kyungbae; Kim, Yougjun; Cho, Jungho; Kim, Dong-Yoon; Kang, Moon-Jin

    2017-01-01

    Galvanized steel is widely used and its demand is growing in automotive industry due to high quality requirement for corrosion resistance. Although there are a lot of demands on using galvanized steel as automotive parts especially for outer body, it has a grave flaw in its welding process. The difficulty is low weldability due to various defects such as porosities and blow holes in weldment, which occurred during welding. A solution to prevent these defects is using hybrid welding process, with two more welding processes. One of the hybrid solutions is using Gas tungsten arc welding (GTAW) as leading position in order to remove the zinc (Zn) coating on the surface before the followed practical fusion welding process. In this research, a numerical analysis model which can predict the eliminated Zn coated layers and the area of Fusion zone (FZ). Developed numerical analysis model was validated through comparing experiment to simulation. Basically, arc heat flux, arc pressure, electromagnetic force and Marangoni flow were employed as the boundary conditions and body force terms. Governing equations such as the continuity, momentum, Volume of fluid (VOF) and energy equations were adopted as usual. In addition to previous model, concentrated arc heat flux and contact thermal conductance models are newly suggested and showed successful result. They are adopted to realize edge concentrated arc and interfacial thermal conductance in lap joint fillet arc welding. Developed numerical analysis model successfully simulated the weld pool and temperature profile therefore the predicted Zn removed area considerably coincided with experimental result.

  9. In temperature forming of friction stir lap welds in aluminium alloys

    Science.gov (United States)

    Bruni, Carlo; Cabibbo, Marcello; Greco, Luciano; Pieralisi, Massimiliano

    2018-05-01

    The objective of such investigation is the study in depth of the forming phase of welds realized on three sheet metal blanks in aluminium alloys by friction stir lap welding. Such forming phase was performed by upsetting at different constant forming temperatures varying from 200°C to 350°C with constant ram velocities of 0.01 and 0.1 mm/s. The temperature values were obtained by the use of heating strips applied on the upper tool and on the lower tool. It was observed an increase in the friction factor, acting at the upsetting tool-workpiece interface, with increasing temperature that is very useful in producing the required localized deformation with which to improve the weld. It was also confirmed that the forming phase allows to realize a required thickness in the weld area allowing to neglect the surficial perturbation produced by the friction stir welding tool shoulder. The obtained thickness could be subjected to springback when too low temperatures are considered.

  10. Corrosion Performance of Friction Stir Linear Lap Welded AM60B Joints

    Science.gov (United States)

    Kish, J. R.; Birbilis, N.; McNally, E. M.; Glover, C. F.; Zhang, X.; McDermid, J. R.; Williams, G.

    2017-11-01

    A corrosion investigation of friction stir linear lap welded AM60B joints used to fabricate an Mg alloy-intensive automotive front end sub-assembly was performed. The stir zone exhibited a slightly refined grain size and significant break-up and re-distribution of the divorced Mg17Al12 (β-phase) relative to the base material. Exposures in NaCl (aq) environments revealed that the stir zone was more susceptible to localized corrosion than the base material. Scanning vibrating electrode technique measurements revealed differential galvanic activity across the joint. Anodic activity was confined to the stir zone surface and involved initiation and lateral propagation of localized filaments. Cathodic activity was initially confined to the base material surface, but was rapidly modified to include the cathodically-activated corrosion products in the filament wake. Site-specific surface analyses revealed that the corrosion observed across the welded joint was likely linked to variations in Al distribution across the surface film/metal interface.

  11. Analysis on the Fracture of Al-Cu Dissimilar Materials Friction Stir Welding Lap Joint

    Science.gov (United States)

    Sun, Hongyu; Zhou, Qi; Zhu, Jun; Peng, Yong

    2017-12-01

    Friction stir welding (FWS) is regarded as a more plausible alternative to other welding methods for Al-Cu dissimilar joining. However, the structure of an FSW joint is different from others. In this study, lap joints of 6061 aluminum alloy and commercially pure copper were produced by FSW, and the effects of rotation rate on macromorphology, microstructure and mechanical properties were investigated. In addition, a fracture J integral model was used to analyze the effect of microstructure on the mechanical properties. The results revealed that the macrodefect-free joints were obtained at a feed rate of 150 mm/min and 1100 rpm and that the failure load of the joint reached as high as 4.57 kN and only reached 2.91 kN for the 900 rpm, where tunnel defects were identified. Particle-rich zones composed of Cu particles dispersed in an Al matrix, and "Flow tracks" were observed by the EDS. The J integral results showed that the microdefects on the advancing side cause serious stress concentration compared with the microdefects located on the Al-Cu interface, resulting in the fracture of the joints.

  12. Playground slide-related injuries in preschool children: increased risk of lower extremity injuries when riding on laps.

    Science.gov (United States)

    Jennissen, Charles A; Koos, Maggie; Denning, Gerene

    2018-04-10

    The purpose of this study was to better understand the factors associated with playground slide-related injuries in preschool children and to test the hypothesis that riding on laps increases the likelihood of lower extremity injuries. Playground slide-related injuries (product code 1242) in children ≤5 years of age treated in emergency departments from 2002 to 2015 were identified (N = 12,686) using the U.S. Consumer Product Safety Commission's National Electronic Injury Surveillance System (NEISS). Descriptive and comparative analyses, including chi-square testing and binary logistic regression, were performed. Based on NEISS stratified national sampling estimates, over 350,000 children ≤5 years of age were injured on slides from 2002 to 2015. Overall, 59% of the children were male, and 65% were white. Almost 60% of injuries occurred in parks or other public areas. The most frequent diagnosis was a fracture (36%); lacerations were 19% of the injuries. A higher proportion of musculoskeletal injuries were seen in toddlers < 3 years old as compared to those 3-5 years of age (p < 0.001). Injuries to the lower extremities increased in frequency as age decreased, whereas injuries to the upper extremities and head/neck/face were more common in older preschoolers. Children < 3 years of age were 12 times more likely to be identified from narratives as being on another person's lap at the time of injury. Children identified as being on a lap had an increased odds of injury to the lower extremity than to other body parts (OR 43.0, 95% confidence interval (CI) 32.0-58.0), and of lower leg/ankle fracture than fractures elsewhere (OR 49.5, 95% CI 31.7-77.4). Decreasing age was associated with a higher likelihood of being identified as sliding down on another person's lap and a higher likelihood of lower extremity injuries. Healthcare providers should be mindful of the potential for these slide-related injuries as they can result in a toddler's fracture of

  13. “Mne govorjat, kakaja bednost’ slovarja...” Il protosamizdat del periodo staliniano alla ricerca di un’espressività

    Directory of Open Access Journals (Sweden)

    Massimo Maurizio

    2015-07-01

    Full Text Available L’estetica della letteratura afferente al circuito samizdat dopo il XX congresso del PCUS (1956 è strettamente legata alla produzione non ufficiale del periodo staliniano, a sua volta definitasi secondo una relazione antitetica alla poesia proletaria degli anni Venti. Molte delle figure di rife- rimento di questo periodo hanno attinto il proprio linguaggio e gli strumenti poetici dall'arsenale espressivo e formale del Secolo d’Argento, sebbene differenziadosene notevolmente e adattan- dolo all'estetica che essi perseguivano, intimamente alternativa a quella realsocialista. La com- plessa poetica di autori quali E. Kropivnickij, Jan Satunovskj (come anche, in un periodo succes- sivo, il “discepolo” del primo G Sapgir e molti altri hanno attinto i tratti distintivi della propria produzione dalla rielaborazione dell’arte proletaria della prima metà degli anni Venti alla luce di una visione dissacrante e grottesca della contemporaneità, che emerge in primo luogo dall'aspetto delle loro opere poetiche.

  14. DIDATTICA DELLA CHIMICA E TRASPOSIZIONE DIDATTICA Parte seconda - Un’approccio didattico alla costruzione del concetto di trasformazione chimica

    Directory of Open Access Journals (Sweden)

    Elena Ghibaudi

    2016-12-01

    Full Text Available Questa seconda parte illustra un esempio di trasposizione didattica realizzata in Italia, in classi della scuola secondaria di II grado. Oggetto della trasposizione sono i concetti di trasformazione chimica, di reazione chimica e di equazione di reazione; un risultato di questo percorso è l’introduzione della distinzione fra le nozioni di atomo e molecola da parte degli allievi stessi, come ipotesi necessaria per interpretare la fenomenologia osservata. L’approccio adottato in questa sequenza è di tipo storico-epistemologico e la prassi mediante la quale viene realizzata è socio-costruttivista. Lo strumento didattico è la situazione-problema. Nella prima parte di questo articolo vengono presentate le attività che consentono agli studenti di elaborare il concetto di trasformazione chimica a partire dal concetto di identità di una sostanza chimica e dall’utilizzo del modello particellare. Nella seconda parte vengono presentate le attività di apprendimento che partendo dal contrasto fra le idee di Dalton (atomo indivisibile e quelle di Gay-Lussac (legge di combinazione dei gas portano alle ipotesi di Avogadro e alla distinzione fra molecole e atomi operata da Cannizzaro.

  15. A feasibility study for experimentally determining dynamic force distribution in a lap joint

    Energy Technology Data Exchange (ETDEWEB)

    Mayes, Randall Lee [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2013-11-01

    Developing constitutive models of the physics in mechanical joints is currently stymied by inability to measure forces and displacements within the joint. The current state of the art estimates whole joint stiffness and energy loss per cycle from external measured force input and one or two acceleration responses. To validate constitutive models beyond this state requires a measurement of the distributed forces and displacements at the joint interface. Unfortunately, introducing measurement devices at the interface completely disrupts the desired physics. A feasibility study is presented for a non-intrusive method of solving for the interface dynamic forces from an inverse problem using full field measured responses. The responses come from the viewable surface of a beam. The noise levels associated with digital image correlation and continuous scanning laser Doppler velocimetry are evaluated from typical beam experiments. Two inverse problems are simulated. One utilizes the extended Sum of Weighted Accelerations Technique (SWAT). The second is a new approach dubbed the method of truncated orthogonal forces. These methods are much more robust if the contact patch geometry is well identified. Various approaches to identifying the contact patch are investigated, including ion marker tracking, Prussian blue and ultrasonic measurements. A typical experiment is conceived for a beam which has a lap joint at one end with a single bolt connecting it to another identical beam. In a virtual test using the beam finite element analysis, it appears that the SWAT inverse method requires evaluation of too many coefficients to adequately identify the force distribution to be viable. However, the method of truncated orthogonal forces appears viable with current digital image correlation (and probably other) imaging techniques.

  16. LapOntoSPM: an ontology for laparoscopic surgeries and its application to surgical phase recognition.

    Science.gov (United States)

    Katić, Darko; Julliard, Chantal; Wekerle, Anna-Laura; Kenngott, Hannes; Müller-Stich, Beat Peter; Dillmann, Rüdiger; Speidel, Stefanie; Jannin, Pierre; Gibaud, Bernard

    2015-09-01

    The rise of intraoperative information threatens to outpace our abilities to process it. Context-aware systems, filtering information to automatically adapt to the current needs of the surgeon, are necessary to fully profit from computerized surgery. To attain context awareness, representation of medical knowledge is crucial. However, most existing systems do not represent knowledge in a reusable way, hindering also reuse of data. Our purpose is therefore to make our computational models of medical knowledge sharable, extensible and interoperational with established knowledge representations in the form of the LapOntoSPM ontology. To show its usefulness, we apply it to situation interpretation, i.e., the recognition of surgical phases based on surgical activities. Considering best practices in ontology engineering and building on our ontology for laparoscopy, we formalized the workflow of laparoscopic adrenalectomies, cholecystectomies and pancreatic resections in the framework of OntoSPM, a new standard for surgical process models. Furthermore, we provide a rule-based situation interpretation algorithm based on SQWRL to recognize surgical phases using the ontology. The system was evaluated on ground-truth data from 19 manually annotated surgeries. The aim was to show that the phase recognition capabilities are equal to a specialized solution. The recognition rates of the new system were equal to the specialized one. However, the time needed to interpret a situation rose from 0.5 to 1.8 s on average which is still viable for practical application. We successfully integrated medical knowledge for laparoscopic surgeries into OntoSPM, facilitating knowledge and data sharing. This is especially important for reproducibility of results and unbiased comparison of recognition algorithms. The associated recognition algorithm was adapted to the new representation without any loss of classification power. The work is an important step to standardized knowledge and data

  17. A new design of the LAPS land surface scheme for use over and through heterogeneous and non-heterogeneous surfaces: Numerical simulations and tests

    Science.gov (United States)

    Mihailovic, Dragutin T.; Lazic, Jelena; Leśny, Jacek; Olejnik, Janusz; Lalic, Branislava; Kapor, Darko; Cirisan, Ana

    2010-05-01

    Numerical simulations and tests with the recently redesigned land-air parameterization scheme (LAPS) are presented. In all experiments, supported either by one-point micrometeorological, 1D or 3D simulations, the attention has been directed to: (1) comparison of simulation outputs, expressing the energy transfer over and through heterogeneous and non-heterogeneous surfaces, versus observations and (2) analysis of uncertainties occurring in the solution of the energy balance equation at the land-air interface. To check the proposed method for aggregation of albedo, "propagating hole" sensitivity tests with LAPS over a sandstone rock grid cell have been performed with the forcing meteorological data for July 17, 1999 in Baxter site, Philadelphia (USA). Micrometeorological and biophysical measurements from the surface experiments conducted over crops and apple orchard in Serbia, Poland, Austria and France were used to test the operation of LAPS in calculating surface fluxes and canopy environment temperatures within and above plant covers of different densities. In addition, sensitivity tests with single canopy covers over the Central Europe region and comparison against the observations taken from SYNOP data using 3D simulations were made. Validation of LAPS performances over a solid surface has been done by comparison of 2 m air temperature observations against 5-day simulations over the Sahara Desert rocky ground using 3D model. To examine how realistically the LAPS simulates surface processes over a heterogeneous surface, we compared the air temperature measured at 2 m and that predicted by the 1D model with the LAPS as the surface scheme. Finally, the scheme behaviour over urban surface was tested by runs over different parts of a hypothetical urban area. The corresponding 1D simulations were carried out with an imposed meteorological dataset collected during HAPEX-MOBILHY experiment at Caumont (France). The quantities predicted by the LAPS compare well with the

  18. Lipid Accumulation Product (LAP) and Visceral Adiposity Index (VAI) as Markers of Insulin Resistance and Metabolic Associated Disturbances in Young Argentine Women with Polycystic Ovary Syndrome.

    Science.gov (United States)

    Abruzzese, Giselle A; Cerrrone, Gloria E; Gamez, Juan M; Graffigna, Mabel N; Belli, Susana; Lioy, Gustavo; Mormandi, Eduardo; Otero, Patricia; Levalle, Oscar A; Motta, Alicia B

    2017-01-01

    Polycystic ovary syndrome (PCOS) is an endocrine disorder. PCOS women are at high risk of developing insulin resistance (IR) and cardiovascular disorders since young age. We aimed to study the reliability of lipid accumulation product (LAP) and visceral adiposity index (VAI) as markers of metabolic disturbances (MD) associated with IR in young reproductive aged PCOS patients. We also evaluated the association between LAP and VAI and the presence of hyperandrogenism. In a cross-sectional study, 110 PCOS patients and 88 control women (18-35 years old) were recruited. PCOS patients were divided into 2 groups, as hyperandrogenic and non-hyperandrogenic considering the signs of hyperandrogenism (clinical or biochemical). Anthropometric measurements were taken and blood samples collected. Metabolic and anthropometric characteristics and their association with IR and associated MD were evaluated and LAP and VAI were calculated. LAP and VAI were compared with TC/HDL-c and TG/HDL-c to define the best markers of MD in this population. Independently of the phenotype, young PCOS patients showed high IR and dyslipidemia. Both LAP and VAI showed to be more effective markers to assess MD and IR in these young women than TG/HDL-c or TC/HDL-c [cut-off values: LAP: 18.24 (sensitivity: 81.43% specificity: 73.49%), positive predictive value (PPV): 75.0%, negative predictive value (NPV): 77.27%, VAI: 2.19 (sensitivity: 81.16% specificity: 72.15% PPV: 74.65% NPV: 72.22%)]. LAP and VAI are representative markers to assess MD associated with IR in young PCOS patients. All PCOS patients, independently of their androgenic condition, showed high metabolic risk. © Georg Thieme Verlag KG Stuttgart · New York.

  19. Lap shear strength of selected adhesives (epoxy, varnish, B-stage glass cloth) in liquid nitrogen and at room temperature

    International Nuclear Information System (INIS)

    Froelich, K.J.; Fitzpatrick, C.M.

    1976-12-01

    The adhesives included several epoxy resins, a varnish, and a B-stage glass cloth (a partially cured resin in a fiberglass cloth matrix). Several parameters critical to bond strength were varied: adhesive and adherend differences, surface preparation, coupling agents, glass cloth, epoxy thickness, fillers, and bonding pressure and temperature. The highest lap shear strengths were obtained with the B-shear glass cloth at both liquid nitrogen and room temperatures with values of approximately 20 MPa (3000 psi) and approximately 25.5 MPa (3700 psi) respectively

  20. Quantification of character-impacting compounds in Ocimum basilicum and 'Pesto alla Genovese' with selected ion flow tube mass spectrometry.

    Science.gov (United States)

    Amadei, Gianluca; Ross, Brian M

    2012-02-15

    Basil (Ocimum basilicum) is an important flavourant plant which constitutes the major ingredient of the pasta sauce 'Pesto alla Genovese'. The characteristic smell of basil stems mainly from a handful of terpenoids (methyl cinnamate, eucalyptol, linalool and estragole), the concentration of which varies according to basil cultivars. The simple and rapid analysis of the terpenoid constituents of basil would be useful as a means to optimise harvesting times and to act as a quality control process for basil-containing foodstuffs. Classical analytical techniques such as gas chromatography/mass spectrometry (GC/MS) are, however, slow, technically demanding and therefore less suitable for routine analysis. A new chemical ionisation technique which allows real-time quantification of traces gases, Selected Ion Flow Tube Mass Spectrometry (SIFT-MS), was therefore utilised to determine its usefulness for the assay of terpenoid concentrations in basil and pesto sauce headspace. Trace gas analysis was performed using the NO(+) precursor ion which minimised interference from other compounds. Character-impacting compound concentration was measured in basil headspace with good reproducibility and statistically significant differences were observed between cultivars. Quantification of linalool in pesto sauce headspace proved more difficult due to the presence of interfering compounds. This was resolved by careful selection of reaction product ions which allowed us to detect differences between various commercial brands of pesto. We conclude that SIFT-MS may be a valid tool for the fast and reproducible analysis of flavourant terpenoids in basil and basil-derived foodstuffs. Copyright © 2011 John Wiley & Sons, Ltd.

  1. Effect of confinement on bond strength of hot-dip galvanized lap splices in concrete structures

    International Nuclear Information System (INIS)

    Fakhran, Mazen

    2004-01-01

    Galvanizing the reinforcing steel is one of the methods used to protect bars against corrosion. Galvanizing is a hot dip process where the reinforcing bars are immersed in an aqueous pre flux solution of zinc ammonium chloride at a controlled temperature between 840 and 850 degrees F. In 2001, a research program was started at AUB to evaluate experimentally the effect of hot dip galvanizing on the bond capacity of tension lap splices anchored in full-scale beam specimens designed to fail in bond splitting mode. The test results indicated that the use of galvanized bars had a negligible effect on bond strength of reinforcement in normal strength. However, galvanizing caused an average of 20 percent decrease in bond strength of reinforcement in high strength concrete. The primary objective of research reported in this thesis, is the need to find a solution to eliminate the bond reduction of galvanized bars in high strength concrete. It is significant to evaluate the positive effect of the addition of transverse reinforcement in the splice region. The hypothesis to be tested is that such transverse reinforcement will insure uniform bond stress distribution over the entire splice region, thus mobilizing all bar lugs along the splice in the stress transfer mechanism between the bar and the surrounding concrete. Such mechanism might reduce the significant decrease in bond strength in high strength concrete due to galvanizing. To achieve this objective, eighteen full-scale beam specimens were tested in positive bending. Each beam was reinforced with bars spliced in a constant moment region at midspam. The splice length was chosen in such a way that the beams failed in bond splitting of the concrete cover in the splice region. The main variables were type of coating (black or galvanized bars), bar size (20, 25 and 32 mm), and amount of transverse reinforcement in the splice region (0, 2 or 4 stirrups). The test results indicated that confinement did not have a significant

  2. Dissimilar joining of galvanized high-strength steel to aluminum alloy in a zero-gap lap joint configuration by two-pass laser welding

    International Nuclear Information System (INIS)

    Ma, Junjie; Harooni, Masoud; Carlson, Blair; Kovacevic, Radovan

    2014-01-01

    Highlights: • Defect-free two-pass laser partially penetrated lap joint of galvanized steel to aluminum was achieved. • The thickness of the Al-rich intermetallic compounds could be controlled by optimal parameters. • The dynamic behavior of the molten pool and keyhole were monitored by a high speed charge-coupled device camera. • The presence of zinc in the intermetallic compounds could improve the strength of the lap joints. - Abstract: A welding procedure based on using two-pass laser scans is introduced for dissimilar joining of overlapped galvanized high-strength dual-phase (DP) steel DP590 to aluminum alloy (AA) 6061 sheets. The first pass is based on a defocused laser spot that scans across the top of the two overlapped sheets and heats the zinc coating at the faying surface to be melted and partially vaporized, while the second pass is executed with a focused laser spot in order to perform the welding. Completely defect-free galvanized steel to aluminum lap joints were obtained by using this two-pass laser welding procedure. An on-line machine vision system was applied to monitor the keyhole dynamics during the laser welding process. An energy-dispersive X-ray spectroscopy (EDS) was carried out to determine the atomic percent of zinc, aluminum, and iron in the galvanized steel to aluminum lap joints. Mechanical testing and micro-hardness test were conducted to evaluate the mechanical properties of the galvanized steel to aluminum lap joints. The experimental results showed that the lap joint of galvanized steel to aluminum obtained by the two-pass laser welding approach had a higher failure value than those joints obtained when the zinc at the faying surface was mechanically removed under the same welding speed and laser power

  3. Defect features, texture and mechanical properties of friction stir welded lap joints of 2A97 Al-Li alloy thin sheets

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Haiyan [State Key Laboratory of Solidification Processing, Northwestern Polytechnical University, Xi' an 710072 (China); Shaanxi Key Laboratory of Friction Welding Technologies, Northwestern Polytechnical University, Xi' an 710072 (China); Fu, Li, E-mail: fuli@nwpu.edu.cn [State Key Laboratory of Solidification Processing, Northwestern Polytechnical University, Xi' an 710072 (China); Shaanxi Key Laboratory of Friction Welding Technologies, Northwestern Polytechnical University, Xi' an 710072 (China); Liang, Pei; Liu, Fenjun [Shaanxi Key Laboratory of Friction Welding Technologies, Northwestern Polytechnical University, Xi' an 710072 (China)

    2017-03-15

    1.4 mm 2A97 Al-Li alloy thin sheets were welded by friction stir lap welding using the stirring tools with different pin length at different rotational speeds. The influence of pin length and rotational speed on the defect features and mechanical properties of lap joints were investigated in detail. Microstructure observation shows that the hook defect geometry and size mainly varies with the pin length instead of the rotational speed. The size of hook defects on both the advancing side (AS) and the retreating side (RS) increased with increasing the pin length, leading to the effective sheet thickness decreased accordingly. Electron backscatter diffraction analysis reveals that the weld zones, especially the nugget zone (NZ), have the much lower texture intensity than the base metal. Some new texture components are formed in the thermo-mechanical affected zone (TMAZ) and the NZ of joint. Lap shear test results show that the failure load of joints generally decreases with increasing the pin length and the rotational speed. The joints failed during the lap shear tests at three locations: the lap interface, the RS of the top sheet and the AS of the bottom sheet. The fracture locations are mainly determined by the hook defects. - Highlights: • Hook defect size mainly varies with the pin length of stirring tool. • The proportion of LAGBs and substructured grains increases from NZ to TMAZ. • Weld zones, especially the NZ, have the much lower texture intensity than the BM. • Lap shear failure load and fracture location of joints is relative to the hook defects.

  4. Defect features, texture and mechanical properties of friction stir welded lap joints of 2A97 Al-Li alloy thin sheets

    International Nuclear Information System (INIS)

    Chen, Haiyan; Fu, Li; Liang, Pei; Liu, Fenjun

    2017-01-01

    1.4 mm 2A97 Al-Li alloy thin sheets were welded by friction stir lap welding using the stirring tools with different pin length at different rotational speeds. The influence of pin length and rotational speed on the defect features and mechanical properties of lap joints were investigated in detail. Microstructure observation shows that the hook defect geometry and size mainly varies with the pin length instead of the rotational speed. The size of hook defects on both the advancing side (AS) and the retreating side (RS) increased with increasing the pin length, leading to the effective sheet thickness decreased accordingly. Electron backscatter diffraction analysis reveals that the weld zones, especially the nugget zone (NZ), have the much lower texture intensity than the base metal. Some new texture components are formed in the thermo-mechanical affected zone (TMAZ) and the NZ of joint. Lap shear test results show that the failure load of joints generally decreases with increasing the pin length and the rotational speed. The joints failed during the lap shear tests at three locations: the lap interface, the RS of the top sheet and the AS of the bottom sheet. The fracture locations are mainly determined by the hook defects. - Highlights: • Hook defect size mainly varies with the pin length of stirring tool. • The proportion of LAGBs and substructured grains increases from NZ to TMAZ. • Weld zones, especially the NZ, have the much lower texture intensity than the BM. • Lap shear failure load and fracture location of joints is relative to the hook defects.

  5. Dal materiale all’immateriale. Verso un approccio sostenibile alla gestione nel contesto glocale / From material to immaterial: towards a sustainable approach to management in the glocal context

    Directory of Open Access Journals (Sweden)

    Mara Cerquetti

    2015-02-01

    Full Text Available Il saggio ripercorre le principali tappe del dibattito internazionale che negli ultimi anni ha condotto ad una nozione di cultural heritage aperta e dinamica, volta al superamento del dualismo tra materiale e immateriale e attenta al ruolo delle comunità locali nei processi di riconoscimento, tutela e valorizzazione del patrimonio stesso. Dopo aver preso in esame l’apporto degli studi giuridici, con specifico riferimento al contesto italiano, si analizza il contributo delle scienze sociali, soprattutto manageriali, particolarmente sensibili al tema della sostenibilità delle politiche e delle azioni finalizzate alla valorizzazione del patrimonio culturale materiale e immateriale anche attraverso l’applicazione di strumenti partecipativi. In quest’ottica, riconoscendo un ruolo centrale alla governance e alla collaborazione tra attori pubblici e privati che operano in un medesimo contesto, si porta infine l’attenzione sugli ecomusei, come caso esemplare dell’“immateriale che vive nella materialità”, evidenziando i nodi problematici che emergono dall’analisi della realtà italiana e suggerendo possibili linee di ricerca future.   The paper traces the main steps of the international debate that during the last years lead to an open and dynamic notion of cultural heritage, overcoming the dualism between tangible and intangible and considering the role of local communities in the processes of heritage recognition, safeguarding and enhancement. After examining the contribution of legal studies, above all in Italy, the approach of social sciences is analysed, focusing on management. These studies have explored the sustainability of policies and actions towards tangible and intangible cultural heritage enhancement, also through the application of participatory tools. In this perspective, governance and collaboration among different actors working in the same context gain a central role. Finally, the attention is focused on eco

  6. Ultrasonic Welding of Thermoplastic Composite Coupons for Mechanical Characterization of Welded Joints through Single Lap Shear Testing.

    Science.gov (United States)

    Villegas, Irene F; Palardy, Genevieve

    2016-02-11

    This paper presents a novel straightforward method for ultrasonic welding of thermoplastic-composite coupons in optimum processing conditions. The ultrasonic welding process described in this paper is based on three main pillars. Firstly, flat energy directors are used for preferential heat generation at the joining interface during the welding process. A flat energy director is a neat thermoplastic resin film that is placed between the parts to be joined prior to the welding process and heats up preferentially owing to its lower compressive stiffness relative to the composite substrates. Consequently, flat energy directors provide a simple solution that does not require molding of resin protrusions on the surfaces of the composite substrates, as opposed to ultrasonic welding of unreinforced plastics. Secondly, the process data provided by the ultrasonic welder is used to rapidly define the optimum welding parameters for any thermoplastic composite material combination. Thirdly, displacement control is used in the welding process to ensure consistent quality of the welded joints. According to this method, thermoplastic-composite flat coupons are individually welded in a single lap configuration. Mechanical testing of the welded coupons allows determining the apparent lap shear strength of the joints, which is one of the properties most commonly used to quantify the strength of thermoplastic composite welded joints.

  7. Identifying Combination of Friction Stir Welding Parameters to Maximize Strength of Lap Joints of AA2014-T6 Aluminum Alloy

    Directory of Open Access Journals (Sweden)

    Rajendrana C.

    2017-01-01

    Full Text Available AA2014 aluminum alloy (Al-Cu alloy has been widely utilized in fabrication of lightweight structures like aircraft structures, demanding high strength to weight ratio and good corrosion resistance. The fusion welding of these alloys will lead to solidification problems such as hot cracking. Friction stir welding is a new solid state welding process, in which the material being welded does not melt and recast. Lot of research works have been carried out by many researchers to optimize process parameters and establish empirical relationships to predict tensile strength of friction stir welded butt joints of aluminum alloys. However, very few investigations have been carried out on friction stir welded lap joints of aluminum alloys. Hence, in this investigation, an attempt has been made to optimize friction stir lap welding (FSLW parameters to attain maximum tensile strength using statistical tools such as design of experiment (DoE, analysis of variance (ANOVA, response graph and contour plots. By this method, it is found that maximum tensile shear fracture load of 12.76 kN can be achieved if a joint is made using tool rotational speed of 900 rpm, welding speed of 110 mm/min, tool shoulder diameter of 12 mm and tool tilt angle of 1.5°.

  8. Influence of the Aluminium Alloy Type on Defects Formation in Friction Stir Lap Welding of Thin Sheets

    Directory of Open Access Journals (Sweden)

    M. I. Costa

    Full Text Available Abstract The weldability in Friction Stir Lap Welding (FSLW of heat and non-heat treatable aluminium alloys, the AA6082-T6 and the AA5754-H22 aluminium alloys, respectively, are compared. For both alloys, welds were produced in very thin sheets, using the same welding parameters and procedures, and strong differences in welds morphology were found. The strength of the welds was evaluated by performing tensile-shear tests under monotonic and cyclic loading conditions. As-welded and heat-treated samples of the AA6082- T6 were tested. It was found that the heat-treatable alloy is more sensitive to defects formation, in lap welding, than the non-heat-treatable alloy. The presence of defects has a strong influence on the monotonic and fatigue behaviour of the welds. In spite of this, for very high-applied stresses, the heat-treatable alloy welds perform better in fatigue than the non-heat-treatable alloy welds.

  9. Transcriptional regulation of miR-146b by C/EBPβ LAP2 in esophageal cancer cells

    International Nuclear Information System (INIS)

    Li, Junxia; Shan, Fabo; Xiong, Gang; Wang, Ju-Ming; Wang, Wen-Lin; Xu, Xueqing; Bai, Yun

    2014-01-01

    Highlights: • MiR-146b promotes esophageal cancer cell proliferation. • MiR-146b inhibits esophageal cancer cell apoptosis. • C/EBPβ directly binds to miR-146b promoter conserved region. • MiR-146b is up-regulated by C/EBPβ LAP2 transcriptional activation. - Abstract: Recent clinical study indicated that up-regulation of miR-146b was associated with poor overall survival of patients in esophageal squamous cell carcinoma. However, the underlying mechanism of miR-146b dysregulation remains to be explored. Here we report that miR-146b promotes cell proliferation and inhibits cell apoptosis in esophageal cancer cell lines. Mechanismly, two C/EBPβ binding motifs are located in the miR-146b promoter conserved region. Among the three isoforms of C/EBPβ, C/EBPβ LAP2 positively regulated miR-146b expression and increases miR-146b levels in a dose-dependent manner through transcription activation of miR-146b gene. Together, these results suggest a miR-146b regulatory mechanism involving C/EBPβ, which may contribute to the up-regulation of miR-146b in esophageal squamous cell carcinoma

  10. Sensitivity Analysis of the Artificial Neural Network Outputs in Friction Stir Lap Joining of Aluminum to Brass

    Directory of Open Access Journals (Sweden)

    Mohammad Hasan Shojaeefard

    2013-01-01

    Full Text Available Al-Mg and CuZn34 alloys were lap joined using friction stir welding while the aluminum alloy sheet was placed on the CuZn34. In addition, the mechanical properties of each sample were characterized using shear tests. Scanning electron microscopy (SEM and X-ray diffraction analysis were used to probe chemical compositions. An artificial neural network model was developed to simulate the correlation between the Friction Stir Lap Welding (FSLW parameters and mechanical properties. Subsequently, a sensitivity analysis was performed to investigate the effect of each input parameter on the output in terms of magnitude and direction. Four methods, namely, the “PaD” method, the “Weights” method, the “Profile” method, and the “backward stepwise” method, which can give the relative contribution and/or the contribution profile of the input factors, were compared. The PaD method, giving the most complete results, was found to be the most useful, followed by the Profile method that gave the contribution profile of the input variables.

  11. La partecipazione dei fedeli laici alla vita pubblica. Testimonianza cristiana, etica pubblica e bene comune nell’insegnamento di Benedetto XVI

    Directory of Open Access Journals (Sweden)

    Fabio Franceschi

    2011-11-01

    Full Text Available Versione riveduta e ampliata, nel testo e nell’apparato bibliografico, della relazione presentata con il titolo “L’impegno dei fedeli laici nella vita pubblica tra responsabilità propria, libertà e dovere di obbedienza al magistero. L’insegnamento di Benedetto XVI” al Convegno di studi “Il fedele laico: realtà e prospettive”, organizzato dalla Pontificia Università della Santa Croce (7-8 aprile 2011. Il contributo è destinato alla pubblicazione negli Atti del Convegno. SOMMARIO: 1. Considerazioni introduttive. Natura essenzialmente laicale della responsabilità politica - 2. L’intervento della Chiesa nel dibattito pubblico su questioni inerenti alla vita sociale e politica. I principi c.d. non negoziabili - 3. Fondamentale libertà dei fedeli rispetto alle indicazioni della gerarchia in materia temporale – 4. La funzione di orientamento dei pastori della comunità ecclesiale e i confini dell’intervento della stessa – 5. I limiti alla libertà dei fedeli in materia temporale: il rapporto tra libertà e verità e la salvaguardia delle esigenze etiche fondamentali e irrinunciabili per il bene comune e della società – 6. Benedetto XVI e l’invito a una nuova generazione di cattolici impegnati in politica. La difesa della centralità della persona umana come compito primario dei credenti impegnati nel governo della città terrena– 7. (segue L’impegno a favore della promozione di un concetto positivo di laicità, aperto alla Trascendenza − 8. (segue La politica come forma singolare di realizzazione della carità – 9. (segue La dottrina sociale della Chiesa come strumento di formazione essenziale e guida sicura per i fedeli laici impegnati nell’ambito socio-politico – 10. Considerazioni conclusive. Doveri, rispettivi, dello Stato e della Chiesa affinché si conservino, o se necessario si creino le condizioni esterne idonee e necessarie allo svolgimento dei compiti dei christifideles laici nella polis.

  12. Promoting energy efficiency: supporting Public Administration and Local Bodies; Promuovere l'efficienza energetica : il supporto alla Pubblica Amministrazione e agli Enti Locali

    Energy Technology Data Exchange (ETDEWEB)

    Fasano, G; Manila, E [Dipartimento tecnologie per l' energia, le fonti rinnovabili e il risparmio energetico, ENEA (Italy)

    2008-11-15

    ENEAS's institutional tasks include technical and scientific support to Public Administration and Local Bodies in the field of energy. Recently such a role has been strengthened by setting up the Agency for Energy Efficiency which ENEA is responsible for. [Italian] Tra i compiti istituzionali dell'ENEA vi e quello di fornire un supporto tecnico scientifico alla PA e agli Enti Locali in tema di energia. Tale ruolo e stato di recente rafforzato con l'istituzione dell'Agenzia per l'Efficienza Energetica affidata all'Ente.

  13. Preliminary results on the fracture analysis of multi-site cracking of lap joints in aircraft skins

    Science.gov (United States)

    Beuth, J. L., Jr.; Hutchinson, John W.

    1992-07-01

    Results of a fracture mechanics analysis relevant to fatigue crack growth at rivets in lap joints of aircraft skins are presented. Multi-site damage (MSD) is receiving increased attention within the context of problems of aging aircraft. Fracture analyses previously carried out include small-scale modeling of rivet/skin interactions, larger-scale two-dimensional models of lap joints similar to that developed here, and full scale three-dimensional models of large portions of the aircraft fuselage. Fatigue testing efforts have included flat coupon specimens, two-dimensional lap joint tests, and full scale tests on specimens designed to closely duplicate aircraft sections. Most of this work is documented in the proceedings of previous symposia on the aging aircraft problem. The effect MSD has on the ability of skin stiffeners to arrest the growth of long skin cracks is a particularly important topic that remains to be addressed. One of the most striking features of MSD observed in joints of some test sections and in the joints of some of the older aircraft fuselages is the relative uniformity of the fatigue cracks from rivet to rivet along an extended row of rivets. This regularity suggests that nucleation of the cracks must not be overly difficult. Moreover, it indicates that there is some mechanism which keeps longer cracks from running away from shorter ones, or, equivalently, a mechanism for shorter cracks to catch-up with longer cracks. This basic mechanism has not been identified, and one of the objectives of the work is to see to what extent the mechanism is revealed by a fracture analysis of the MSD cracks. Another related aim is to present accurate stress intensity factor variations with crack length which can be used to estimate fatigue crack growth lifetimes once cracks have been initiated. Results are presented which illustrate the influence of load shedding from rivets with long cracks to neighboring rivets with shorter cracks. Results are also included

  14. Cross-talk between miR-471-5p and autophagy component proteins regulates LC3-associated phagocytosis (LAP) of apoptotic germ cells.

    Science.gov (United States)

    Panneerdoss, Subbarayalu; Viswanadhapalli, Suryavathi; Abdelfattah, Nourhan; Onyeagucha, Benjamin C; Timilsina, Santosh; Mohammad, Tabrez A; Chen, Yidong; Drake, Michael; Vuori, Kristiina; Kumar, T Rajendra; Rao, Manjeet K

    2017-09-19

    Phagocytic clearance of apoptotic germ cells by Sertoli cells is vital for germ cell development and differentiation. Here, using a tissue-specific miRNA transgenic mouse model, we show that interaction between miR-471-5p and autophagy member proteins regulates clearance of apoptotic germ cells via LC3-associated phagocytosis (LAP). Transgenic mice expressing miR-471-5p in Sertoli cells show increased germ cell apoptosis and compromised male fertility. Those effects are due to defective engulfment and impaired LAP-mediated clearance of apoptotic germ cells as miR-471-5p transgenic mice show lower levels of Dock180, LC3, Atg12, Becn1, Rab5 and Rubicon in Sertoli cells. Our results reveal that Dock180 interacts with autophagy member proteins to constitute a functional LC3-dependent phagocytic complex. We find that androgen regulates Sertoli cell phagocytosis by controlling expression of miR-471-5p and its target proteins. These findings suggest that recruitment of autophagy machinery is essential for efficient clearance of apoptotic germ cells by Sertoli cells using LAP.Although phagocytic clearance of apoptotic germ cells by Sertoli cells is essential for spermatogenesis, little of the mechanism is known. Here the authors show that Sertoli cells employ LC3-associated phagocytosis (LAP) by recruiting autophagy member proteins to clear apoptotic germ cells.

  15. Plant-based oral tolerance to hemophilia therapy employs a complex immune regulatory response including LAP+CD4+ T cells

    OpenAIRE

    Wang, Xiaomei; Su, Jin; Sherman, Alexandra; Rogers, Geoffrey L.; Liao, Gongxian; Hoffman, Brad E.; Leong, Kam W.; Terhorst, Cox; Daniell, Henry; Herzog, Roland W.

    2015-01-01

    Coadministering FIX orally and systemically induces tolerance via complex immune regulation, involving tolerogenic dendritic and T-cell subsets.Induced CD4+CD25−LAP+ regulatory T cells with increased IL-10 and TGF-β expression and CD4+CD25+ regulatory T cells suppress antibody formation against FIX.

  16. Oana M. Oprean, Romania’s Accession to the European Union and Its Impact on the Roma Minority (Saarbrűcken: LAP Lambert Academic Publishing, 2012

    Directory of Open Access Journals (Sweden)

    Henrieta Serban

    2013-03-01

    Full Text Available Review of the book by Oana M. Oprean Romania’s Accession to the European Union and Its Impact on the Roma Minority, Saarbrűcken, LAP Lambert Academic Publishing, 2012, ISBN 978-3-8465-8671-6, 73p.

  17. Introduzione alla fisica matematica

    CERN Document Server

    Persico, Enrico

    1960-01-01

    Cinematica dei mezzi continui, campi scalari e vettoriali ; funzioni armoniche, rappresentazioni confomi ; teoria dell'elasticità ; elettromagnetismo ; conduzione del calore (e diffusione) ; le equazioni a derivate parziali della fisica matematica ; cenni sulla teoria della relatività (ristretta).

  18. Dalla microfisica alla macrofisica

    CERN Document Server

    Caldirola, Piero

    1974-01-01

    La scoperta delle leggi che reggono il micromondo, effettuata dai creatori della fisica quantistica, rappresenta, assieme a quella della relatività, il maggior progresso compiuto dalla fisica nel XX secolo. Fino a poco fa però, malgrado i suoi successi, la meccanica quantistica era ancora mal compresa soprattutto nelle sue conseguenze filosofiche, e fonte di dibattiti senza fine. Spiaceva infatti, come spiace ancora, a molti il dover usare due linguaggi del tutto diversi per descrivere il micro- e il macromondo, per cui la fisica quantistica appariva come un incidente, uno stadio provvisorio nel cammino della scienza. Fu però la stessa ricerca a mettere in evidenza l'esistenza di sistemi macroscopici, quali l'elio liquido, i superconduttori, il laser, descrivibili solamente attraverso le leggi quantistiche. Si comprese allora essere queste un ponte gettato fra il micro- e il macromondo. Il libro vuole illustrare queste leggi in maniera non divulgativa ma concettuale, cioè limitando al minimo l'uso del for...

  19. An N-terminal Retention Module Anchors the Giant Adhesin LapA of Pseudomonas fluorescens at the Cell Surface: A Novel Sub-family of Type I Secretion Systems.

    Science.gov (United States)

    Smith, T Jarrod; Font, Maria E; Kelly, Carolyn M; Sondermann, Holger; O'Toole, George A

    2018-02-05

    LapA of Pseudomonas fluorescens Pf0-1 belongs to a diverse family of cell surface associated bacterial adhesins that are secreted via the type-1 secretion system (T1SS). We previously reported that the periplasmic protease LapG cleaves the N-terminus of LapA at a canonical dialanine motif to release the adhesin from the cell surface under conditions unfavorable to biofilm formation, thus decreasing biofilm formation. Here, we characterize LapA as the first type 1 secreted substrate that does not follow the "one-step" rule of T1SS. Rather, a novel N-terminal element, called the retention module (RM), localizes LapA at the cell surface as a secretion intermediate. Our genetic, biochemical, and molecular modeling analysis support a model wherein LapA is tethered to the cell surface through its T1SS outer membrane TolC-like pore, LapE, until LapG cleaves LapA in the periplasm. We further demonstrate this unusual retention strategy is likely conserved among LapA-like proteins, and reveals a new subclass of T1SS ABC transporters involved in transporting this group of surface-associated, LapA-like adhesins. These studies demonstrate a novel cell surface retention strategy used throughout the Proteobacteria and highlight a previously unappreciated flexibility of function for T1SS. Importance. Bacteria have evolved multiple secretion strategies to interact with their environment. For many bacteria, the secretion of cell surface associated adhesins is key for initiating contact with a preferred substratum to facilitate biofilm formation. Our work demonstrates that P. fluorescens uses a previously unrecognized secretion strategy to retain the giant adhesin LapA at its cell surface. Further, we identify likely LapA-like adhesins in various pathogenic and commensal Proteobacteria and provide phylogenetic evidence that these adhesins are secreted by a new subclass of T1SS ABC transporters. Copyright © 2018 American Society for Microbiology.

  20. Effect of Weld Bead Shape on the Fatigue Behavior of GMAW Lap Fillet Joint in GA 590 MPa Steel Sheets

    Directory of Open Access Journals (Sweden)

    Insung Hwang

    2017-09-01

    Full Text Available In this study, the effect of weld bead shape on the fatigue strength of lap fillet joints using the gas metal arc welding (GMAW process was investigated. The base material used in the experiment was 590 MPa grade galvanealed steel sheet with 2.3 mm and 2.6 mm thickness. In order to make the four types of weld beads with different shapes by factors such as length, angle, and area, the welding process, wire feeding speed, and joint shape were changed. The stress-number of cycles to failure (S–N curve and fatigue strength were obtained from the fatigue test for four types of weld bead, and the cause of the fatigue strength difference was clarified through the analysis of the geometrical factors, such as length, angle, and area of the weld bead. In addition, the relationship between weld bead shape and fatigue strength was discussed.

  1. Study on Flow-Shifted Region Depending on Spool Displacement in Hydraulic Servo Valve with Hybrid Lap

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Hwanghun; Yun, Sonam; Lee, Sungsoo [Korea Institute of Machinery and Materials, Daejeon (Korea, Republic of); Yang, Jooho [Pukyong Nat' l Univ., Busan (Korea, Republic of)

    2013-03-15

    This study examined the static characteristics of a spool valve with a hybrid lap between the spool land and the sleeve. The static equation for the pressure characteristics was derived from flow equations that depend on the spool displacement, and the final model was derived from q{sub a}=q{sub b}=0 because the pressure characteristics test needs to block the control port in the valve. The static equation for the flow characteristics was derived from the pressure characteristics when the control port is open (q{sub a}=q{sub b}, p{sub a}=p{sub b}). The characteristic equation in the shifted region was assumed from the proportional relationship between the pressure-flow characteristics and the spool displacement.

  2. Experimental Strength of Single-Lap Hybrid Joints on Woven Fabric Kenaf Fiber Composites Under Quasi Static Condition

    Directory of Open Access Journals (Sweden)

    Yee Lee Sim

    2016-01-01

    Full Text Available For the past decades, usage of natural fiber reinforced composites in low bearing load applications are increasing tremendously due to drawbacks concerning the use of synthetic fibers. Kenaf fibers have a good potential to be used as composite reinforcements as they possesses excellent fiber strength compared to own self-weight. Current work concentrates on mechanical properties of woven fabric kenaf composites with single-lap hybrid joints configurations. Four width to diameter ratio, (W/d of cross-ply lay-up joints as designed in testing series were tested by using quasi static mechanical testing. Experimental results showed that the failure load increased with the increasing of W/d ratios. Thinner lay-up had better bearing strength compared to thicker lay-up as found in current study.

  3. Experimental Investigation and Finite Element Analysis on Fatigue Behavior of Aluminum Alloy 7050 Single-Lap Joints

    Science.gov (United States)

    Zhou, Bing; Cui, Hao; Liu, Haibo; Li, Yang; Liu, Gaofeng; Li, Shujun; Zhang, Shangzhou

    2018-03-01

    The fatigue behavior of single-lap four-riveted aluminum alloy 7050 joints was investigated by using high-frequency fatigue test and scanning electron microscope (SEM). Stress distributions obtained by finite element (FE) analysis help explain the fatigue performance. The fatigue test results showed that the fatigue lives of the joints depend on cold expansion and applied cyclic loads. FE analysis and fractography indicated that the improved fatigue lives can be attributed to the reduction in maximum stress and evolution of fatigue damage at the critical location. The beneficial effects of strengthening techniques result in tearing ridges or lamellar structure on fracture surface, decrease in fatigue striations spacing, delay of fatigue crack initiation, crack deflection in fatigue crack propagation and plasticity-induced crack closure.

  4. Tool geometry, rotation and travel speeds effects on the properties of dissimilar magnesium/aluminum friction stir welded lap joints

    International Nuclear Information System (INIS)

    Mohammadi, J.; Behnamian, Y.; Mostafaei, A.; Gerlich, A.P.

    2015-01-01

    Highlights: • Tool geometry, rotation and travel speeds show great effect on the microstructure stability of FSW joint. • Increasing rotation and travel speeds resulted in increasing the tensile strength and ductility of the joints. • Better intermixing between Al/Mg alloys was obtained by tapered threaded pin. • A mechanical interlocking mechanism proposed for higher ductility and superior tensile properties in FSW joints. - Abstract: Lap joint friction stir welding (FSW) between dissimilar AZ31B and Al 6061 alloys sheets was conducted using various welding parameters including tool geometry, rotation and travel speeds. Tapered threaded pin and tapered pin tools were applied to fabricate FSW joints, using different rotation and travel speeds. Metallurgical investigations including X-ray diffraction pattern (XRD), optical microscopy images (OM), scanning electron microscopy equipped with an energy-dispersive X-ray spectroscopy (SEM–EDS) and electron probe microanalysis (EPMA) were used to characterize joints microstructures made with different welding parameters. Intermetallic phases were detected in the weld zone (WZ). Various microstructures were observed in the stir zone which can be attributed to using different travel and rotation speeds. Mechanical evaluation including lap shear fracture load test and microhardness measurements indicated that by simultaneously increasing the tool rotation and travel speeds, the joint tensile strength and ductility reached a maximum value. Microhardness studies and extracted results from stress–strain curves indicated that mechanical properties were affected by FSW process. Furthermore, phase analyses by XRD indicated the presence of intermetallic compounds in the weld zone. Finally, in the Al/Mg dissimilar weld, fractography studies showed that intermetallic compounds formation in the weld zone had an influence on the failure mode

  5. Electroacupuncture for postoperative pain and gastrointestinal motility after laparoscopic appendectomy (AcuLap): study protocol for a randomized controlled trial.

    Science.gov (United States)

    Kim, Gangmi

    2015-10-14

    Acupuncture is a widely serviced complementary medicine. Although acupuncture is suggested for managing postoperative ileus and pain, supporting evidence is weak. The AcuLap trial is designed to provide high-level evidence regarding whether or not electroacupuncture is effective in promoting gastrointestinal motility and controlling pain after laparoscopic surgery. This study is a prospective randomized controlled trial with a three-arm, parallel-group structure evaluating the efficacy of electroacupuncture for gastrointestinal motility and postoperative pain after laparoscopic appendectomy. Patients with appendicitis undergoing laparoscopic surgery are included and randomized into three groups: 1) electroacupuncture group, 2) sham acupuncture group, and 3) control group. Patients receive 1) acupuncture with electrostimulation or 2) fake electroacupuncture with sham device twice a day or 3) no acupuncture after laparoscopic appendectomy. The primary outcome is time to first passing flatus after operation. Secondary outcomes include postoperative pain, analgesics, nausea/vomiting, bowel motility, time to tolerable diet, complications, hospital stay, readmission rates, time to recovery, quality of life, medical costs, and protocol failure rate. Patients and hospital staff (physicians and nurses) are blinded to which group the patient is assigned, electroacupuncture or sham acupuncture. Data analysis personnel are blinded to group assignment among all three groups. Estimated sample size to detect a minimum difference of time to first flatus with 80 % power, 5 % significance, and 10 % drop rate is 29 × 3 groups = 87 patients. Analysis will be performed according to the intention-to-treat principle. The AcuLap trial will provide evidence on the merits and/or demerits of electroacupuncture for bowel motility recovery and pain relief after laparoscopic appendectomy. The trial was registered in Clinical Research Information Service (CRiS), Republic of Korea ( KCT0001486

  6. Investigation on dissimilar underwater friction stir lap welding of 6061-T6 aluminum alloy to pure copper

    International Nuclear Information System (INIS)

    Zhang, Jingqing; Shen, Yifu; Yao, Xin; Xu, Haisheng; Li, Bo

    2014-01-01

    Highlights: • 6061-T6 Al and pure Cu were successfully underwater friction stir lap welded. • The underwater weld was analyzed via comparing with the classical weld. • The oxidation of Cu was prevented via the external water. • The amount of Al–Cu intermetallic was decreased by the external water. • The thickness of Al–Cu diffusion interlayer was decreased by the external water. - Abstract: Friction stir welding (classical FSW) is considered to offer advantages over the traditional fusion welding techniques in terms of dissimilar welding. However, some challenges still exist in the dissimilar friction stir lap welding of the aluminum/copper (Al/Cu) metallic couple, among which the formation of the Al–Cu intermetallic compounds is the major problem. In the present research, due to the fact that the formation and growth of the intermetallic are significantly controlled by the thermal history, the underwater friction stir welding (underwater FSW) was employed for fabricating the weld, and the weld obtained by underwater FSW (underwater weld) was analyzed via comparing with the weld obtained under same parameters by classical FSW (classical weld). In order to investigate the effect of the external water on the thermal history, the K-type thermocouple was utilized to measure the weld temperature, and it is found that the water could decrease the peak temperature and shorten the thermal cycle time. The XRD results illustrate that the interface of the welds mainly consist of the Al–Cu intermetallic compounds such as CuAl 2 and Cu 9 Al 4 together with some amounts of Al and Cu, and it is also found that the amount of the intermetallic in the underwater weld is obvious less than in the classical weld. The SEM images and the EDS line scan results also illustrate that the Al–Cu diffusion interlayer at the Al–Cu interface of the underwater weld was obviously thinner than that of the classical weld

  7. Validation of SINERGIA as training tool: a randomized study to test the transfer of acquired basic psychomotor skills to LapMentor.

    Science.gov (United States)

    Moyano-Cuevas, J L; Sánchez-Margallo, F M; Sánchez-Peralta, L F; Pagador, J B; Enciso, S; Sánchez-González, P; Gómez-Aguilera, E J; Usón-Gargallo, J

    2011-11-01

    Laparoscopic surgery is commonly used in many surgical procedures but requires a learning process to develop the necessary skills. Virtual reality simulators play an essential role within the training curricula. This paper aims to determine whether training in SINERGIA VR simulator allows novice surgeons to improve their basic psychomotor laparoscopic skills. Forty-two people participated in this study, including 28 unexperience medical students and 14 expert surgeons who developed previously more than 100 laparoscopic procedures. Medical students made a pre-training test in LapMentor II; then, they trained in SINERGIA and they finally accomplished a post-training test in LapMentor II. Experts just made one trial in LapMentor II. A statistical analysis was carried out and results of pre- and post-training tests of novices were compared with Wilcoxon signed-rank test. Pre- and post-training tests of novices were also compared with results of experts with Mann-Whitney U test. Most metrics provided by LapMentor II and included in this study show significant differences when comparing pre- and post-training tests of novices. Analysis of pre-training test of novices and experts results show significant differences in all analyzed metrics for all studied tasks. On the other hand, LapMentor was not able to distinguish between experts and novices after training in SINERGIA for any metric in the camera manipulation task and for some metrics of the other tasks. Training in SINERGIA VR simulator allows improvement of basic psychomotor laparoscpic skills and transferring them to another virtual simulator. Therefore, it could be used in laparoscopic surgery training programs.

  8. Sopravvivenza e dispersione della lepre comune (Lepus europaeus Pallas, 1778 in relazione alla densità di popolazione e alle caratteristiche ambientali

    Directory of Open Access Journals (Sweden)

    Francesca Pella

    2003-10-01

    Full Text Available La presente ricerca è stata effettuata con lo scopo di valutare la sopravvivenza di lepri autoctone non traslocate in relazione alle caratteristiche ambientali e alla densità di popolazione. Inoltre è stata analizzata la capacità delle lepri di colonizzare territori a bassa densità, al di fuori delle aree protette, al fine di ricavare indicazioni utili per una gestione della lepre basata sulla corretta pianificazione delle aree protette. Lo studio è stato effettuato dal gennaio del 1999 al luglio del 2001 in due Zone di Ripopolamento e Cattura della Pianura Padana, caratterizzate da colture a seminativi irrigui una (Vistarino e colture a seminativi asciutti l?altra (Portalbera. Per determinare la densità di popolazione sono stati effettuati, in primavera ed autunno, censimenti notturni da autovettura, con proiettore alogeno orientabile manualmente. Per analizzare la sopravvivenza, l?uso dello spazio e la dispersione sono state catturate, con reti a tramaglio, valutate (peso, sesso, classe d?età e condizioni sanitarie e radiomarcate 16 lepri a Vistarino e 20 a Portalbera. I censimenti hanno evidenziato una differenza tra le due aree nelle densità che sono risultate comprese tra gli 11 ed i 20 individui per km² a Vistarino e tra i 29 e gli 83 a Portalbera. La sopravvivenza media delle lepri radiomarcate è stata di 295,5 giorni (ES=43,2, considerando le aree cumulate, e la probabilità di sopravvivenza nel periodo di studio è risultata pari a 0,36 (ES=0,094. Nell?area di studio di Vistarino la sopravvivenza media è stata di 426,4 giorni (ES=61,6 e la probabilità di sopravvivenza di 0,67 (ES=0,12 mentre a Portalbera la sopravvivenza media era di 142,2 giorni (ES=13,9 con una probabilità di sopravvivenza di 0,00 (ES=0,00. La dimensione media dell?area vitale per tutte le lepri catturate in entrambe le aree è stata pari a 47,9 ha (ES=6,08; minimo=0,01; massimo=171,1 se calcolata con il metodo del Minimo Poligono Convesso, mentre era di

  9. Xenopus LAP2β protein knockdown affects location of lamin B and nucleoporins and has effect on assembly of cell nucleus and cell viability.

    Science.gov (United States)

    Dubińska-Magiera, Magda; Chmielewska, Magdalena; Kozioł, Katarzyna; Machowska, Magdalena; Hutchison, Christopher J; Goldberg, Martin W; Rzepecki, Ryszard

    2016-05-01

    Xenopus LAP2β protein is the single isoform expressed in XTC cells. The protein localizes on heterochromatin clusters both at the nuclear envelope and inside a cell nucleus. The majority of XLAP2β fraction neither colocalizes with TPX2 protein during interphase nor can be immunoprecipitated with XLAP2β antibody. Knockdown of the XLAP2β protein expression in XTC cells by synthetic siRNA and plasmid encoded siRNA resulted in nuclear abnormalities including changes in shape of nuclei, abnormal chromatin structure, loss of nuclear envelope, mislocalization of integral membrane proteins of INM such as lamin B2, mislocalization of nucleoporins, and cell death. Based on timing of cell death, we suggest mechanism associated with nucleus reassembly or with entry into mitosis. This confirms that Xenopus LAP2 protein is essential for the maintenance of cell nucleus integrity and the process of its reassembly after mitosis.

  10. Novel Ambler class A beta-lactamase LAP-1 and its association with the plasmid-mediated quinolone resistance determinant QnrS1.

    Science.gov (United States)

    Poirel, Laurent; Cattoir, Vincent; Soares, Ana; Soussy, Claude-James; Nordmann, Patrice

    2007-02-01

    The plasmid-mediated quinolone resistance determinant QnrS1 was identified in non-clonally related Enterobacter cloacae isolates in association with a transferable narrow-spectrum beta-lactam resistance marker. Cloning experiments allowed the identification of a novel Ambler class A beta-lactamase, named LAP-1. It shares 62 and 61% amino acid identity with the most closely related beta-lactamases, TEM-1 and SHV-1, respectively. It has a narrow-spectrum hydrolysis of beta-lactams and is strongly inhibited by clavulanic acid and sulbactam and, to a lesser extent, by tazobactam. Association of the blaLAP-1 gene with the qnrS1 gene was identified in E. cloacae isolates from France and Vietnam. These genes were plasmid located and associated with similar insertion sequences but were not associated with sul1-type class 1 integrons, as opposed to the qnrA genes.

  11. Characterization of waste of soda-lime glass generated from lapping process to reuse as filler in composite materials as thermal insulation

    Directory of Open Access Journals (Sweden)

    A. C. P. Galvão

    2015-09-01

    Full Text Available AbstractThe beneficiation plate process by soda-lime glass lapping in the glass industry generates, an untapped residue (waste. The waste of this material is sent to landfills, causing impact on the environment. This work aimed to characterize and evaluate the waste of soda-lime glass (GP lapping. After its acquisition, the GP was processed by grinding and sieving and further characterized by the chemical/mineralogical analysis (XRF, EDS and XRD, SEM morphology, particle size by laser diffraction, thermogravimetric analyses (TGA and DSC and thermophysical analyses. It was observed that the GP particles are irregular and micrometric with the predominant presence of Na, Si and Ca elements characteristic of amorphous soda-lime glass. The assessment of the chemical/mineralogical, morphological, thermophysical and thermal gravimetric characteristics of GP suggest its reuse as reinforcing fillers or filler in composite materials to obtain thermal insulation.

  12. Adhesives: Test Method, Group Assignment, and Categorization Guide for High-Loading-Rate Applications Preparation and Testing of Single Lap Joints (Ver. 2.2, Unlimited)

    Science.gov (United States)

    2016-04-01

    the characteristics of these data and relationships among their corresponding entities, supporting one or more application areas.”2 Digital...application, and cure) of an adhesive with unfamiliar handling characteristics . Fig. 2 Surface treating the lap-joint coupon panel using the acetone...bonding surface. It is crucial to not touch the treated tabs (specifically, the bonding area), even with gloves, after treatment is completed. Bake

  13. Influence of tool geometry and rotational speed on mechanical properties and defect formation in friction stir lap welded 5456 aluminum alloy sheets

    International Nuclear Information System (INIS)

    Salari, Emad; Jahazi, Mohammad; Khodabandeh, Alireza; Ghasemi-Nanesa, Hadi

    2014-01-01

    Highlights: • Successful lap joint friction stir welding of AA5456 with two different tempers. • New stepped conical threaded pin for FSW of lap joints is introduced. • Investigated interactions between tool geometry and mechanical properties. • Microstructure and fracture surface analysis of dissimilar lap welds. - Abstract: Friction stir welding of AA5456 aluminum alloy in lap joint configuration is with two different tempers, T321 and O, and different thicknesses, 5 mm and 2.5 mm was investigated. The influences of tool geometry and various rotational speeds on macrostructure, microstructure and joint strength are presented. Specifically, four different tool pin profiles (a conical thread pin, a cylindrical–conical thread pin, a stepped conical thread pin and Flared Triflute pin tool) and two rotational speeds, 600 and 800 rpm, were used. The results indicated that, tool geometry influences significantly material flow in the nugget zone and accordingly control the weld mechanical properties. Of particular interest is the stepped conical threaded pin, which is introduced for the first time in the present investigation. Scanning electron microscopy investigation of the fracture location of samples was carried out and the findings correlated with tool geometry features and their influences on material flow and tension test results. The optimum microstructure and mechanical properties were obtained for the joints produced with the stepped conical thread pin profile and rotational speed of 600 rpm. The characteristics of the nugget zone microstructure, hooking height, and fracture location of the weld joints were used as criteria to quantify the influence of processing conditions on joint performance and integrity. The results are interpreted in the framework of physical metallurgy properties and compared with published literature

  14. Reconstruction of fiber Bragg grating strain profile used to monitor the stiffness degradation of the adhesive layer in carbon fiber–reinforced plastic single-lap joint

    OpenAIRE

    Song Chunsheng; Zhang Jiaxiang; Yang Mo; Shang Erwei; Zhang Jinguang

    2017-01-01

    The adhesive-bonded joint of carbon fiber–reinforced plastic is one of the core components in aircraft structure design. It is an effective guarantee for the safety and reliability of the aerospace aircraft structure to use effective methods for monitoring and early warning of internal failure. In this article, the mapping relation model between the strain profiles of the adherend of the carbon fiber–reinforced plastic single-lap adhesive joint and the stiffness degradation evolution of adhes...

  15. The Fundamentals of Laparoscopic Surgery and LapVR evaluation metrics may not correlate with operative performance in a novice cohort

    Science.gov (United States)

    Steigerwald, Sarah N.; Park, Jason; Hardy, Krista M.; Gillman, Lawrence; Vergis, Ashley S.

    2015-01-01

    Background Considerable resources have been invested in both low- and high-fidelity simulators in surgical training. The purpose of this study was to investigate if the Fundamentals of Laparoscopic Surgery (FLS, low-fidelity box trainer) and LapVR (high-fidelity virtual reality) training systems correlate with operative performance on the Global Operative Assessment of Laparoscopic Skills (GOALS) global rating scale using a porcine cholecystectomy model in a novice surgical group with minimal laparoscopic experience. Methods Fourteen postgraduate year 1 surgical residents with minimal laparoscopic experience performed tasks from the FLS program and the LapVR simulator as well as a live porcine laparoscopic cholecystectomy. Performance was evaluated using standardized FLS metrics, automatic computer evaluations, and a validated global rating scale. Results Overall, FLS score did not show an association with GOALS global rating scale score on the porcine cholecystectomy. None of the five LapVR task scores were significantly associated with GOALS score on the porcine cholecystectomy. Conclusions Neither the low-fidelity box trainer or the high-fidelity virtual simulator demonstrated significant correlation with GOALS operative scores. These findings offer caution against the use of these modalities for brief assessments of novice surgical trainees, especially for predictive or selection purposes. PMID:26641071

  16. The Fundamentals of Laparoscopic Surgery and LapVR evaluation metrics may not correlate with operative performance in a novice cohort

    Directory of Open Access Journals (Sweden)

    Sarah N. Steigerwald

    2015-12-01

    Full Text Available Background: Considerable resources have been invested in both low- and high-fidelity simulators in surgical training. The purpose of this study was to investigate if the Fundamentals of Laparoscopic Surgery (FLS, low-fidelity box trainer and LapVR (high-fidelity virtual reality training systems correlate with operative performance on the Global Operative Assessment of Laparoscopic Skills (GOALS global rating scale using a porcine cholecystectomy model in a novice surgical group with minimal laparoscopic experience. Methods: Fourteen postgraduate year 1 surgical residents with minimal laparoscopic experience performed tasks from the FLS program and the LapVR simulator as well as a live porcine laparoscopic cholecystectomy. Performance was evaluated using standardized FLS metrics, automatic computer evaluations, and a validated global rating scale. Results: Overall, FLS score did not show an association with GOALS global rating scale score on the porcine cholecystectomy. None of the five LapVR task scores were significantly associated with GOALS score on the porcine cholecystectomy. Conclusions: Neither the low-fidelity box trainer or the high-fidelity virtual simulator demonstrated significant correlation with GOALS operative scores. These findings offer caution against the use of these modalities for brief assessments of novice surgical trainees, especially for predictive or selection purposes.

  17. Detection of defects in laser welding of AZ31B magnesium alloy in zero-gap lap joint configuration by a real-time spectroscopic analysis

    Science.gov (United States)

    Harooni, Masoud; Carlson, Blair; Kovacevic, Radovan

    2014-05-01

    The effect of surface oxide layer existing at the lap-joint faying surface of magnesium sheets is investigated on the keyhole dynamics of the weld pool and weld bead qualities. It is observed that by removing the oxide layer from the faying surface of the lap joint, a high quality weld can be achieved in the laser welding process. However, the presence of an oxide layer deteriorates the quality of the weld by forming pores at the interface of the two overlapped sheets. The purpose of this paper is to identify the correlation between the integrity of the weld and the interaction between the laser and material. A spectroscopy sensor was applied to detect the spectra emitted from a plasma plume during the laser welding of AZ31B magnesium alloy in a zero-gap lap joint configuration. The electron temperature was calculated by applying a Boltzmann plot method based on the detected spectra, and the correlation between the pore formation and the spectral signals was studied. The laser molten pool and the keyhole condition were monitored in real-time by a high speed charge-coupled device (CCD) camera. A green laser was used as an illumination source in order to detect the influence of the oxide layer on the dynamic behavior of the molten pool. Results revealed that the detected spectrum and weld defects had a meaningful correlation for real-time monitoring of the weld quality during laser welding of magnesium alloys.

  18. Respectability, morality and disgust in the night‐time economy: exploring reactions to ‘lap dance’ clubs in England and Wales

    Science.gov (United States)

    Hubbard, Phil; Colosi, Rachela

    2015-01-01

    Abstract The night‐time economy is often described as repelling consumers fearful of the ‘undesirable Others’ imagined dominant within such time‐spaces. In this paper we explore this by describing attitudes towards, and reactions to, one particularly contentious site: the ‘lap dance’ club. Often targeted by campaigners in England and Wales as a source of criminality and anti‐sociality, in this paper we shift the focus from fear to disgust, and argue that Sexual Entertainment Venues (SEVs) are opposed on the basis of moral judgments that reflect distinctions of both class and gender. Drawing on documentary analysis, survey results and interview data collected during guided walks, we detail the concerns voiced by those anxious about the presence of lap dance or striptease clubs in their town or city, particularly the notion that they ‘lower the tone’ of particular streets or neighbourhoods. Our conclusion is that the opposition expressed to lap dance clubs is part of an attempt to police the boundaries of respectable masculinities and femininities, marginalizing the producers and consumers of sexual entertainment through ‘speech acts’ which identify such entertainment as unruly, vulgar and uncivilized. These findings are considered in the light of ongoing debates concerning the relations of morality, respectability and disgust. PMID:27708460

  19. Examination of pulsed eddy current for inspection of second layer aircraft wing lap-joint structures using outlier detection methods

    Energy Technology Data Exchange (ETDEWEB)

    Butt, D.M., E-mail: Dennis.Butt@forces.gc.ca [Royal Military College of Canada, Dept. of Chemistry and Chemical Engineering, Kingston, Ontario (Canada); Underhill, P.R.; Krause, T.W., E-mail: Thomas.Krause@rmc.ca [Royal Military College of Canada, Dept. of Physics, Kingston, Ontario (Canada)

    2016-09-15

    Ageing aircraft are susceptible to fatigue cracks at bolt hole locations in multi-layer aluminum wing lap-joints due to cyclic loading conditions experienced during typical aircraft operation, Current inspection techniques require removal of fasteners to permit inspection of the second layer from within the bolt hole. Inspection from the top layer without fastener removal is desirable in order to minimize aircraft downtime while reducing the risk of collateral damage. The ability to detect second layer cracks without fastener removal has been demonstrated using a pulsed eddy current (PEC) technique. The technique utilizes a breakdown of the measured signal response into its principal components, each of which is multiplied by a representative factor known as a score. The reduced data set of scores, which represent the measured signal, are examined for outliers using cluster analysis methods in order to detect the presence of defects. However, the cluster analysis methodology is limited by the fact that a number of representative signals, obtained from fasteners where defects are not present, are required in order to perform classification of the data. Alternatively, blind outlier detection can be achieved without having to obtain representative defect-free signals, by using a modified smallest half-volume (MSHV) approach. Results obtained using this approach suggest that self-calibrating blind detection of cyclic fatigue cracks in second layer wing structures in the presence of ferrous fasteners is possible without prior knowledge of the sample under test and without the use of costly calibration standards. (author)

  20. Dual-beam laser welding of AZ31B magnesium alloy in zero-gap lap joint configuration

    Science.gov (United States)

    Harooni, Masoud; Carlson, Blair; Kovacevic, Radovan

    2014-03-01

    Porosity within laser welds of magnesium alloys is one of the main roadblocks to achieving high quality joints. One of the causes of pore formation is the presence of pre-existing coatings on the surface of magnesium alloy such as oxide or chromate layers. In this study, single-beam and dual-beam laser heat sources are investigated in relation to mitigation of pores resulting from the presence of the as-received oxide layer on the surface of AZ31B-H24 magnesium alloy during the laser welding process. A fiber laser with a power of up to 4 kW is used to weld samples in a zero-gap lap joint configuration. The effect of dual-beam laser welding with different beam energy ratios is studied on the quality of the weld bead. The purpose of this paper is to identify the beam ratio that best mitigates pore formation in the weld bead. The laser molten pool and the keyhole condition, as well as laser-induced plasma plume are monitored in real-time by use of a high speed charge-coupled device (CCD) camera assisted with a green laser as an illumination source. Tensile and microhardness tests were used to measure the mechanical properties of the laser welded samples. Results showed that a dual-beam laser configuration can effectively mitigate pore formation in the weld bead by a preheating-welding mechanism.

  1. Influence of Interface Gap on the Stress Behaviour of Smart Single Lap Joints Under Time Harmonic Load

    Directory of Open Access Journals (Sweden)

    Ivanova Jordanka

    2017-06-01

    Full Text Available Adhesive joints are frequently used in different composite structures due to their improved mechanical performance and better understanding of the failure mechanics. The application of such structures can be seen in aerospace and high technology components. The authors developed and applied modified shear lag analysis to investigate the hygrothermalpiezoelectric response of a smart single lap joint at environmental conditions (with/without an interface gap along the overlap zone and under dynamic time harmonic mechanical and electric loads. The main key is the study of the appearance of possible delamination along the interface. As illustrative examples, the analytical closed form solution of the structure shear and the axial stresses response, as well as the interface debond length, including influence of mechanical, piezoelectric, thermal characteristics and frequencies is performed and discussed. All results are presented in figures. The comparison of the shear stress and electric fields for both cases of overlap zone (continuous or with a gap is also shown in figures and discussed.

  2. Experimental and Numerical Investigations of Fretting Fatigue Behavior for Steel Q235 Single-Lap Bolted Joints

    Directory of Open Access Journals (Sweden)

    Yazhou Xu

    2016-01-01

    Full Text Available This work aims to investigate the fretting fatigue life and failure mode of steel Q235B plates in single-lap bolted joints. Ten specimens were prepared and tested to fit the S-N curve. SEM (scanning electron microscope was then employed to observe fatigue crack surfaces and identify crack initiation, crack propagation, and transient fracture zones. Moreover, a FEM model was established to simulate the stress and displacement fields. The normal contact stress, tangential contact stress, and relative slipping displacement at the critical fretting zone were used to calculate FFD values and assess fretting fatigue crack initiation sites, which were in good agreement with SEM observations. Experimental results confirmed the fretting fatigue failure mode for these specimens. It was found that the crack initiation resulted from wear regions at the contact surfaces between plates, and fretting fatigue cracks occurred at a certain distance away from hole edges. The proposed FFD-N relationship is an alternative approach to evaluate fretting fatigue life of steel plates in bolted joints.

  3. Development of a novel ex vivo porcine laparoscopic Heller myotomy and Nissen fundoplication training model (Toronto lap-Nissen simulator).

    Science.gov (United States)

    Ujiie, Hideki; Kato, Tatsuya; Hu, Hsin-Pei; Bauer, Patrycja; Patel, Priya; Wada, Hironobu; Lee, Daiyoon; Fujino, Kosuke; Schieman, Colin; Pierre, Andrew; Waddell, Thomas K; Keshavjee, Shaf; Darling, Gail E; Yasufuku, Kazuhiro

    2017-06-01

    Surgical trainees are required to develop competency in a variety of laparoscopic operations. Developing laparoscopic technical skills can be difficult as there has been a decrease in the number of procedures performed. This study aims to develop an inexpensive and anatomically relevant model for training in laparoscopic foregut procedures. An ex vivo , anatomic model of the human upper abdomen was developed using intact porcine esophagus, stomach, diaphragm and spleen. The Toronto lap-Nissen simulator was contained in a laparoscopic box-trainer and included an arch system to simulate the normal radial shape and tension of the diaphragm. We integrated the use of this training model as a part of our laparoscopic skills laboratory-training curriculum. Afterwards, we surveyed trainees to evaluate the observed benefit of the learning session. Twenty-five trainees and five faculty members completed a survey regarding the use of this model. Among the trainees, only 4 (16%) had experience with laparoscopic Heller myotomy and Nissen fundoplication. They reported that practicing with the model was a valuable use of their limited time, repeating the exercise would be of additional benefit, and that the exercise improved their ability to perform or assist in an actual case in the operating room. Significant improvements were found in the following subjective measures comparing pre- vs. post-training: (I) knowledge level (5.6 vs. 8.0, Pmyotomy and fundoplication.

  4. Effect of Abrasive Waterjet Peening Surface Treatment of Steel Plates on the Strength of Single-Lap Adhesive Joints

    Directory of Open Access Journals (Sweden)

    Kamil Anasiewicz

    2017-09-01

    Full Text Available The paper presents results of comparative study of shear strength of single–lap adhesive joints, depending on the method of surface preparation of steel plates with increased corrosion resistance. The method of preparing adherend surfaces is often one of the most important factors determining the strength of adhesive joints. Appropriate geometric surface development and cleaning of the surface enhances adhesion forces between adherend material and adhesive. One of the methods of shaping engineering materials is waterjet cutting, which in the AWJP – abrasive waterjet peening variant, serves to shape flat surfaces of the material by changing the roughness and introducing stresses into the surface layer. These changes are valuable when preparing adhesive joints. In the study, surface roughness parameters obtained with AWJP treatment, were analyzed in direct relation to the strength of the adhesive joint. As a consequence of the experimental results analysis, the increase in the strength of the adhesive joints was observed in a certain range of parameters used for AWJP treatment. A decrease in shear strength of adhesive joint with the most modified topography of overlap surface was observed.

  5. I = 2 ππ scattering phase shift from the HAL QCD method with the LapH smearing

    Science.gov (United States)

    Kawai, Daisuke; Aoki, Sinya; Doi, Takumi; Ikeda, Yoichi; Inoue, Takashi; Iritani, Takumi; Ishii, Noriyoshi; Miyamoto, Takaya; Nemura, Hidekatsu; Sasaki, Kenji

    2018-04-01

    Physical observables, such as the scattering phase shifts and binding energy, calculated from the non-local HAL QCD potential do not depend on the sink operators used to define the potential. In practical applications, the derivative expansion of the non-local potential is employed, so that physical observables may receive some scheme dependence at a given order of the expansion. In this paper, we compare the I=2ππ scattering phase shifts obtained in the point-sink scheme (the standard scheme in the HAL QCD method) and the smeared-sink scheme (the LapH smearing newly introduced in the HAL QCD method). Although potentials in different schemes have different forms as expected, we find that, for reasonably small smearing size, the resultant scattering phase shifts agree with each other if the next-to-leading-order (NLO) term is taken into account. We also find that the HAL QCD potential in the point-sink scheme has a negligible NLO term for a wide range of energies, which implies good convergence of the derivative expansion, while the potential in the smeared-sink scheme has a non-negligible NLO contribution. The implications of this observation for future studies of resonance channels (such as the I=0 and 1ππ scatterings) with smeared all-to-all propagators are briefly discussed.

  6. Investigation on the Effect of Pulsed Energy on Strength of Fillet Lap Laser Welded AZ31B Magnesium Alloys

    Science.gov (United States)

    Salleh, M. N. M.; Ishak, M.; Aiman, M. H.; Idris, S. R. A.; Romlay, F. R. M.

    2017-09-01

    AZ31B magnesium alloy have been hugely applied in the aerospace, automotive, and electronic industries. However, welding thin sheet AZ31B was challenging due to its properties which is easily to evaporated especially using conventional fusion welding method such as metal inert gas (MIG). Laser could be applied to weld this metal since it produces lower heat input. The application of fiber laser welding has been widely since this type of laser could produce better welding product especially in the automotive sectors. Low power fiber laser was used to weld this non-ferrous metal where pulse wave (PW) mode was used. Double fillet lap joint was applied to weld as thin as 0.6 mm thick of AZ31B and the effect of pulsed energy on the strength was studied. Bond width, throat length, and penetration depth also was studied related to the pulsed energy which effecting the joint. Higher pulsed energy contributes to the higher fracture load with angle of irradiation lower than 3 °

  7. Influence of Zn Interlayer on Interfacial Microstructure and Mechanical Properties of TIG Lap-Welded Mg/Al Joints

    Science.gov (United States)

    Gao, Qiong; Wang, Kehong

    2016-03-01

    This study explored 6061 Al alloy and AZ31B Mg alloy joined by TIG lap welding with Zn foils of varying thicknesses, with the additional Zn element being imported into the fusion zone to alloy the weld seam. The microstructures and chemical composition in the fusion zone near the Mg substrate were examined by SEM and EDS, and tensile shear strength tests were conducted to investigate the mechanical properties of the Al/Mg joints, as well as the fracture surfaces, and phase compositions. The results revealed that the introduction of an appropriate amount of Zn transition layer improves the microstructure of Mg/Al joints and effectively reduces the formation of Mg-Al intermetallic compounds (IMCs). The most common IMCs in the fusion zone near the Mg substrate were Mg-Zn and Mg-Al-Zn IMCs. The type and distribution of IMCs generated in the weld zone differed according to Zn additions; Zn interlayer thickness of 0.4 mm improved the sample's mechanical properties considerably compared to thicknesses of less than 0.4 mm; however, any further increase in Zn interlayer thickness of above 0.4 mm caused mechanical properties to deteriorate.

  8. Examination of pulsed eddy current for inspection of second layer aircraft wing lap-joint structures using outlier detection methods

    International Nuclear Information System (INIS)

    Butt, D.M.; Underhill, P.R.; Krause, T.W.

    2016-01-01

    Ageing aircraft are susceptible to fatigue cracks at bolt hole locations in multi-layer aluminum wing lap-joints due to cyclic loading conditions experienced during typical aircraft operation, Current inspection techniques require removal of fasteners to permit inspection of the second layer from within the bolt hole. Inspection from the top layer without fastener removal is desirable in order to minimize aircraft downtime while reducing the risk of collateral damage. The ability to detect second layer cracks without fastener removal has been demonstrated using a pulsed eddy current (PEC) technique. The technique utilizes a breakdown of the measured signal response into its principal components, each of which is multiplied by a representative factor known as a score. The reduced data set of scores, which represent the measured signal, are examined for outliers using cluster analysis methods in order to detect the presence of defects. However, the cluster analysis methodology is limited by the fact that a number of representative signals, obtained from fasteners where defects are not present, are required in order to perform classification of the data. Alternatively, blind outlier detection can be achieved without having to obtain representative defect-free signals, by using a modified smallest half-volume (MSHV) approach. Results obtained using this approach suggest that self-calibrating blind detection of cyclic fatigue cracks in second layer wing structures in the presence of ferrous fasteners is possible without prior knowledge of the sample under test and without the use of costly calibration standards. (author)

  9. Comparison of Corner-Butt 45 (Cb-45 and Corner-Lap (Cl joints in friction stir welding

    Directory of Open Access Journals (Sweden)

    Setiawan Widia

    2018-01-01

    Full Text Available The 10 mm thick Aluminum 6061 plates have been corner joined using varied design and those were 45° Corner Butt and Corner Lap Joints (CB-45 & CL. Friction tool was hardened EMS 45. True experimental method was used with independent parameters is feed rate which varied at 10 mm/min, 15 mm/min and 30 mm/min respectively. Other parameter such as rotating speed was kept constant. Experiment results show that, CB-45 yields better properties than CL. The tensile strength of CB-45 reaches 163.7 MPa for 10 mm/min feed rate. Whilst CL produces joint with tensile strength equal 120 MPa for equal parameters. Microstructure observation showed that CB-45 produces fine and homogenous appearance of MgO compared to CL. This phenomenon is caused by the pin of CB-45 joint which fully penetrates the nugget zone which is not found in CL design. This microstructure in turn promotes higher tensile strength of CB-45.

  10. Metodologie innovative per il supporto alla progettazione e all’analisi delle prestazioni di impianti ad energia solare a concentrazione ed eolici off-shore utilizzando immagini satellitari ottiche e SAR

    OpenAIRE

    Morelli, Marco; Masini, Andrea; Alberto, Marco; Potenza, Marco Alberto Carlo

    2014-01-01

    In questo lavoro presentiamo delle nuove metodologie, sviluppate nell’ambito del progetto SATENERG (Servizi sATellitari per le ENergie Rinnovabili di nuova Generazione) finanziato dall’Agenzia Spaziale Italiana, sia per il supporto alla progettazione/pianificazione che per il monitoraggio quasi in tempo reale e l’analisi delle prestazioni degli impianti ad energia rinnovabile di nuova generazione (CSP, CPV ed eolici off-shore) utilizzando immagini satellitari. In particolare pe...

  11. Long-term, repeated dose in vitro neurotoxicity of the glutamate receptor antagonist L-AP3, demonstrated in rat hippocampal slice cultures by using continuous propidium iodide incubation.

    Science.gov (United States)

    Kristensen, Bjarne W; Blaabjerg, Morten; Noraberg, Jens; Zimmer, Jens

    2007-05-01

    Most in vitro models are only used to assess short-term effects of test compounds. However, as demonstrated here, hippocampal slice cultures can be used for long-term studies. The test compound used was the metabotropic glutamate receptor antagonist, L(+)-2-amino-3-phosphonopropionic acid (L-AP3), which is known to be toxic in vivo after subchronic, but not acute, administration. Degenerative effects were monitored by measuring the cellular uptake of propidium iodide (PI; continuously present in the medium) and lactate dehydrogenase (LDH) leakage, and by using a panel of histological stains. Hippocampal slices, derived from 2-3 day old rats and grown for 3 weeks, were subsequently exposed for the next 3 weeks to 0, 10 or 100microM L-AP3, with PI (2microM) in the culture medium. Exposure to 100microM L-AP3 induced severe toxicity after 4-6 days, shown by massive PI uptake, LDH leakage, changes in MAP2 and GFAP immunostaining, and in Nissl and Timm staining. In contrast, 10microM L-AP3 did not induce detectable neuronal degeneration. Treatment with the NMDA receptor antagonist, MK-801, or the AMPA/KA receptor antagonist NBQX, together with 100microM L-AP3, reduced neurodegeneration down to close to control values. It is concluded that continuous incubation of hippocampal slice cultures with PI is technically feasible for use in studies of inducible neuronal degeneration over time.

  12. Computed vs. conventional radiography for detecting fatigue cracks in riveted lap joints of aeronautical grade hybrid fiber-metal laminate Glare

    International Nuclear Information System (INIS)

    Tarpani, J.R.; Hideki Shinohara, A.; Da Silva, R.R.; Do Val Lacerda, N.

    2007-01-01

    This study aimed at assessing the capability of three different radiographic approaches (two computed or digital, and one conventional or analogous) for imaging fatigue cracks in riveted lap joints of composite fiber-metal laminate Glare. These structural joints are unique in the sense that fatigue cracks develop mainly at the faying surfaces of Glare sheets, so that visual detection is largely prevented and nondestructive inspection becomes mandatory. For this purpose, a round-robin programme comprising several industrial and research centers that employ X-ray radiography routinely to inspect high-demanding equipments, components and structures was conducted. (authors)

  13. Lap-belt syndrome: management of aortic intimal dissection in a 7-year-old child with a constellation of injuries

    International Nuclear Information System (INIS)

    Khanna, Paritosh C.; Bulas, Dorothy I.; Rothenbach, Patricia; Guzzetta, Philip C.

    2007-01-01

    We present a case of lap-belt motor vehicle injury in a 7-year-old male who was admitted with abdominal ecchymoses and pain with associated aortic intimal flap, bowel injury, hemoperitoneum, and retroperitoneal hematoma at initial imaging with CT. Most of these findings were confirmed at subsequent laparotomy, and the patient underwent operative repair of bowel injuries. His aortic intimal flap was followed with US and color Doppler imaging during which time he was treated conservatively until there was sonographic evidence of intimal healing. This patient illustrates a multimodality approach to imaging and conservative management. (orig.)

  14. LAP-BAND for BMI 30-40: 5-year health outcomes from the multicenter pivotal study.

    Science.gov (United States)

    Dixon, J B; Eaton, L L; Vincent, V; Michaelson, R

    2016-02-01

    We performed a 5-year multicenter study to evaluate the safety and effectiveness of the LAP-BAND System surgery (LBS) in patients with obesity with a body mass index (BMI) of 30-39.9 kg m(-)(2). This pivotal study was designed to support LBS application to the US Food and Drug Administration for broadening the indications for surgery and the lower BMI indication was approved with 1-year data in 2011, with the intention to complete the 5-year evaluation. To present broad health outcome data including weight change, patient reported outcomes, comorbidity change and complications during the 5-year study. The study was conducted at seven US private practice clinical trial sites. We enrolled 149 BMI 30-39.9 subjects into a 5-year, multicenter, longitudinal, prospective post-approval study. Data for those completing each time point are presented. The predefined target of at least 30% excess weight loss was achieved by more than 76% of subjects by 1-year and at every year thereafter during the 5-year study. Mean percentage weight loss at 5 years was 15.9±12.4%. Sustained weight loss was accompanied by sustained improvement in generic and weight-specific quality of life, symptoms of depression and the prevalence of binge-eating disorder. The number of subjects with normal fasting triglyceride, high-density lipoprotein cholesterol, plasma glucose and HbA1c increased significantly between baseline and 5 years. Fifty-four months after LBS implantation, the rate of device explants without replacement was 5.4%; however, the rate of explants increased to 12.1% by month 60 owing to no cost-elective band removals offered to subjects at study exit. No deaths or unanticipated adverse device effects were reported. The LBS is safe and effective for people with BMI 30-39.9 with demonstrated improvements in weight loss, comorbidities and quality of life, and with a low explant rate through 5 years following treatment.

  15. Erivajadustega laps / Inga Mutso

    Index Scriptorium Estoniae

    Mutso, Inga, 1959-

    2002-01-01

    Sept. 2000 - märts 2001 viidi Tartu Õppekeskuse, TPÜ täiendkoolituse osakonna ja Geomeedia Erakooli eripedagoogikaalastel täiendusõppe kursustel osalenud pedagoogide seas läbi ankeetküsitlus. Uuringus selgus, et erivajadustega õpilaste integreerimist tavakooli takistab vajaliku väljaõppe saanud pedagoogide puudumine ja koolide mittevalmisolek

  16. Effects of process parameters on microstructure and mechanical properties of friction stir lap linear welded 6061 aluminum alloy to NZ30K magnesium alloy

    Directory of Open Access Journals (Sweden)

    Shuai Tan

    2017-03-01

    Full Text Available The microstructures and lap-shear behaviors of friction stir lap linear welded as-extruded 6061 Al alloy to as-cast Mg–3.0Nd–0.2Zn–0.7Zr (wt.% (NZ30K alloy joints were examined. Various tool rotation and travel speeds were adopted to prepare the joints. The analysis of temperature field indicates that the peak temperature for each sample can reach 450 °C, which exceeds the eutectic reaction temperatures of 437 °C and 450 °C according to the binary phase diagram of Al–Mg system. The fierce intermixing can be found at the interface between Al and Mg alloys, forming the intermetallic of Al3Mg2. Welds with the rotation speed of 900 rpm and travel speed of 120 mm/min display the highest tensile shear failure load of about 2.24 kN. The value was increased by 13% after the sample was heat treated at 400 °C for 0.5 h.

  17. A multi-feature integration method for fatigue crack detection and crack length estimation in riveted lap joints using Lamb waves

    Science.gov (United States)

    He, Jingjing; Guan, Xuefei; Peng, Tishun; Liu, Yongming; Saxena, Abhinav; Celaya, Jose; Goebel, Kai

    2013-10-01

    This paper presents an experimental study of damage detection and quantification in riveted lap joints. Embedded lead zirconate titanate piezoelectric (PZT) ceramic wafer-type sensors are employed to perform in situ non-destructive evaluation (NDE) during fatigue cyclical loading. PZT wafers are used to monitor the wave reflection from the boundaries of the fatigue crack at the edge of bolt joints. The group velocity of the guided wave is calculated to select a proper time window in which the received signal contains the damage information. It is found that the fatigue crack lengths are correlated with three main features of the signal, i.e., correlation coefficient, amplitude change, and phase change. It was also observed that a single feature cannot be used to quantify the damage among different specimens since a considerable variability was observed in the response from different specimens. A multi-feature integration method based on a second-order multivariate regression analysis is proposed for the prediction of fatigue crack lengths using sensor measurements. The model parameters are obtained using training datasets from five specimens. The effectiveness of the proposed methodology is demonstrated using several lap joint specimens from different manufactures and under different loading conditions.

  18. A multi-feature integration method for fatigue crack detection and crack length estimation in riveted lap joints using Lamb waves

    International Nuclear Information System (INIS)

    He, Jingjing; Guan, Xuefei; Peng, Tishun; Liu, Yongming; Saxena, Abhinav; Celaya, Jose; Goebel, Kai

    2013-01-01

    This paper presents an experimental study of damage detection and quantification in riveted lap joints. Embedded lead zirconate titanate piezoelectric (PZT) ceramic wafer-type sensors are employed to perform in situ non-destructive evaluation (NDE) during fatigue cyclical loading. PZT wafers are used to monitor the wave reflection from the boundaries of the fatigue crack at the edge of bolt joints. The group velocity of the guided wave is calculated to select a proper time window in which the received signal contains the damage information. It is found that the fatigue crack lengths are correlated with three main features of the signal, i.e., correlation coefficient, amplitude change, and phase change. It was also observed that a single feature cannot be used to quantify the damage among different specimens since a considerable variability was observed in the response from different specimens. A multi-feature integration method based on a second-order multivariate regression analysis is proposed for the prediction of fatigue crack lengths using sensor measurements. The model parameters are obtained using training datasets from five specimens. The effectiveness of the proposed methodology is demonstrated using several lap joint specimens from different manufactures and under different loading conditions. (paper)

  19. Laparoscopic subtotal hysterectomy using the plasma kinetic and lap loop systems: an alternative approach in the surgical management of women with uterine fibroids.

    Science.gov (United States)

    Erian, John; El-Shawarby, Salem A; Hassan, Mohsen; Wissa, Ihab; Chandakas, Stefanos; Hill, Nicholas

    2008-03-01

    To evaluate the safety and applicability of laparoscopic subtotal hysterectomy (LSH) using the plasma kinetic (PK) and lap loop systems as an alternative surgical approach in the management of uterine fibroids in women who have completed their families. Sixty-two consecutive LSH were performed during this prospective study from March 2003 to March 2005 at Princess Royal University Hospital, Kent, UK. All study patients had menorrhagia resistant to at least one form of therapy, with a mean duration of symptoms of 3.5 years. In addition, four patients had previous myomectomy. The mean number of fibroids removed was 2.7. The mean weight of the uterus was 141.9 g. The mean operative time was 46.8 min, and the mean blood loss was 126.6 mL. The overall perioperative complication rate was 4.8% with no visceral injury, or return to theatre. At follow-up, all patients were satisfied with surgery. The study describes the first application of the PK and Lap Loop systems in LSH for the surgical management of uterine fibroids in women in whom fertility is not an issue, and its findings suggest that this minimally invasive technique is a safe, and valid alternative. Larger adequately-powered studies are however still required.

  20. Reconstruction of fiber Bragg grating strain profile used to monitor the stiffness degradation of the adhesive layer in carbon fiber–reinforced plastic single-lap joint

    Directory of Open Access Journals (Sweden)

    Song Chunsheng

    2017-01-01

    Full Text Available The adhesive-bonded joint of carbon fiber–reinforced plastic is one of the core components in aircraft structure design. It is an effective guarantee for the safety and reliability of the aerospace aircraft structure to use effective methods for monitoring and early warning of internal failure. In this article, the mapping relation model between the strain profiles of the adherend of the carbon fiber–reinforced plastic single-lap adhesive joint and the stiffness degradation evolution of adhesive layer was achieved by finite element software ABAQUS. The fiber Bragg grating was embedded in the adherend between the first and second layers at the end of the adhesive layer to calculate the reflection spectrum of fiber Bragg grating sensor region with improved T-matrix method for reconstruction of the adherend strain profile of fiber Bragg grating sensing area with the help of genetic algorithm. According to the reconstruction results, the maximum error between the ideal and reconstructed strain profile under different tension loads did not exceed 7.43%, showing a good coincidence degree. The monitoring method of the stiffness degradation evolution of adhesive layer of the carbon fiber–reinforced plastic single-lap joint based on the reconstruction of the adherend strain profile of fiber Bragg grating sensing area thus was figured out.

  1. A glorious, yet almost forgotten, mathematical theory, and some possibly new applications of it to physics; Una gloriosa ma quasi dimenticata teoria matematica e certe sue inedite applicazioni alla fisica

    Energy Technology Data Exchange (ETDEWEB)

    Lo Surdo, C. [ENEA, Divisione Fusione Centro Ricerche Frascati, Rome (Italy)

    2001-07-01

    Hardly the role and the importance of Classical-Invariant Theory is the history of mathematics (say, between - 1850 and - 1920) can be fully appreciated by a nonspecialist. In this study, it was firstly purposed to provide a compact sketch of its foundations starting from (and keeping the framework of) some very basic ideas in the equation theory; and then, after reviewing a couple of classical examples, to illustrate a number of (presumably new) applications to physics, with special reference to constitutive relations in continuous material media. As a significant example of the latter type (amongst other ones), it shall be completely worked out the problem of the a priori structure of linear viscous-stress tensor in a magnetoplasma. [Italian] Non e' facile, da parte del non-specialista, apprezzare pienamente il ruolo e l'importanza della Teoria degli Invarianti Classici nella storia della matematica (diciamo all'incirca tra il 1850 e il 1920). In questo studio, il lettore trova anzitutto una rassegna, succinta ma largamente improntata alla generalita', dei suoi fondamenti a partire da poche idee di base della teoria delle equazioni, oltre ad un breve inquadramento storico e alla illustrazione di un paio di esempi classici. Seguono poi alcune applicazion - presuntivamente nuove - alla fisica matematica, con particolare riferimento alle relazioni costitutive in mezzi materiali continui. Come significativo esempio di applicazione di quest'ultimo tipo, e' infine completamente sviluppato il calcolo della struttura a priori del tensore di viscosita' lineare in un magnetoplasma.

  2. Clinical evaluation of the Serum CrossLaps One Step ELISA, a new assay measuring the serum concentration of bone-derived degradation products of type I collagen C-telopeptides

    DEFF Research Database (Denmark)

    Christgau, S; Rosenquist, C; Alexandersen, P

    1998-01-01

    The Serum CrossLaps One Step ELISA is a sandwich assay using two monoclonal antibodies specific for a beta-aspartate form of the epitope EKAHDGGR derived from the carboxy-terminal telopeptide region of type I collagen alpha1-chain. Our objective was to assess the clinical value of the Serum Cross...

  3. Long-term, repeated dose in vitro neurotoxicity of the glutamate receptor antagonist L-AP3, demonstrated in rat hippocampal slice cultures by using continuous propidium iodide incubation

    DEFF Research Database (Denmark)

    Kristensen, Bjarne W; Blaabjerg, Morten; Noraberg, Jens

    2007-01-01

    ), which is known to be toxic in vivo after subchronic, but not acute, administration. Degenerative effects were monitored by measuring the cellular uptake of propidium iodide (PI; continuously present in the medium) and lactate dehydrogenase (LDH) leakage, and by using a panel of histological stains....... Hippocampal slices, derived from 2-3 day old rats and grown for 3 weeks, were subsequently exposed for the next 3 weeks to 0, 10 or 100microM L-AP3, with PI (2microM) in the culture medium. Exposure to 100microM L-AP3 induced severe toxicity after 4-6 days, shown by massive PI uptake, LDH leakage, changes...... in MAP2 and GFAP immunostaining, and in Nissl and Timm staining. In contrast, 10microM L-AP3 did not induce detectable neuronal degeneration. Treatment with the NMDA receptor antagonist, MK-801, or the AMPA/KA receptor antagonist NBQX, together with 100microM L-AP3, reduced neurodegeneration down...

  4. Regulation of adipocyte 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1 by CCAAT/enhancer-binding protein (C/EBP β isoforms, LIP and LAP.

    Directory of Open Access Journals (Sweden)

    Cristina L Esteves

    Full Text Available 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1 catalyses intracellular regeneration of active glucocorticoids, notably in liver and adipose tissue. 11β-HSD1 is increased selectively in adipose tissue in human obesity, a change implicated in the pathogenesis of metabolic syndrome. With high fat (HF-feeding, adipose tissue 11β-HSD1 is down-regulated in mice, plausibly to counteract metabolic disease. Transcription of 11β-HSD1 is directly regulated by members of the CCAAT/enhancer binding protein (C/EBP family. Here we show that while total C/EBPβ in adipose tissue is unaltered by HF diet, the ratio of the C/EBPβ isoforms liver-enriched inhibitor protein (LIP and liver-enriched activator protein (LAP (C/EBPβ-LIP:LAP is increased in subcutaneous adipose. This may cause changes in 11β-HSD1 expression since genetically modified C/EBPβ((+/L mice, with increased C/EBPβ-LIP:LAP ratio, have decreased subcutaneous adipose 11β-HSD1 mRNA levels, whereas C/EBPβ(ΔuORF mice, with decreased C/EBPβ-LIP:LAP ratio, show increased subcutaneous adipose 11β-HSD1. C/EBPβ-LIP:LAP ratio is regulated by endoplasmic reticulum (ER stress and mTOR signalling, both of which are altered in obesity. In 3T3-L1 adipocytes, 11β-HSD1 mRNA levels were down-regulated following induction of ER stress by tunicamycin but were up-regulated following inhibition of mTOR by rapamycin. These data point to a central role for C/EBPβ and its processing to LIP and LAP in transcriptional regulation of 11β-HSD1 in adipose tissue. Down-regulation of 11β-HSD1 by increased C/EBPβ-LIP:LAP in adipocytes may be part of a nutrient-sensing mechanism counteracting nutritional stress generated by HF diet.

  5. Role of C/EBPβ-LAP and C/EBPβ-LIP in early adipogenic differentiation of human white adipose-derived progenitors and at later stages in immature adipocytes.

    Science.gov (United States)

    Lechner, Stefan; Mitterberger, Maria C; Mattesich, Monika; Zwerschke, Werner

    2013-01-01

    We investigated the role of the major isoforms of CCAAT enhancer binding protein β (C/EBPβ), C/EBPβ-LAP and C/EBPβ-LIP, in adipogenesis of human white adipose-derived stromal/progenitor cells (ASC). C/EBPβ gene expression was transiently induced early in adipogenesis. At later stages, in immature adipocytes, the C/EBPβ mRNA and protein levels declined. The C/EBPβ-LIP protein steady-state level decreased considerably stronger than the C/EBPβ-LAP level and the C/EBPβ-LIP half-life was significantly shorter than the C/EBPβ-LAP half-life. The turn-over of both C/EBPβ-isoforms was regulated by ubiquitin/proteasome-dependent degradation. These data suggest that the protein stability of the C/EBPβ-isoforms is differentially regulated in the course of adipogenesis and in immature adipocytes. Constitutive overexpression of C/EBPβ-LIP had antiadipogenic activity in human ASC. C/EBPβ-LAP, which promotes adipogenesis in mouse 3T3-L1 preadipocytes by directly activating expression of the adipogenic keyregulator PPARγ2, induced the expression of PPARγ2 and of the adipocyte differentiation gene product FABP4 in confluent ASC in the absence of adipogenic hormones. At later stages after hormone cocktail-induced adipogenesis, in immature adipocytes, constitutive overexpression of C/EBPβ-LAP led to reduced expression of PPARγ2 and FABP4, C/EBPα expression was downregulated and the expression of the adipocyte differentiation gene products adiponectin and leptin was impaired. These findings suggest that constitutive overexpression of C/EBPβ-LAP induces adipogenesis in human ASC and negatively regulates the expression of adipogenic regulators and certain adipocyte differentiation gene products in immature adipocytes. We conclude the regulation of both C/EBPβ gene expression and C/EBPβ-LIP and C/EBPβ-LAP protein turn-over plays an important role for the expression of adipogenic regulators and/or adipocyte differentiation genes in early adipogenic differentiation of

  6. 3D finite element analysis of stress distributions and strain energy release rates for adhesive bonded flat composite lap shear joints having pre-existing delaminations

    Energy Technology Data Exchange (ETDEWEB)

    Parida, S. K.; Pradhan, A. K. [Indian Institute of Technology, Bhubaneswar (India)

    2014-02-15

    The rate of propagation of embedded delamination in the strap adherend of lap shear joint (LSJ) made of carbon/epoxy composites has been evaluated employing three-dimensional non-linear finite elements. The delamination has been presumed to pre-exist in the thin resin layer between the first and second plies of the strap adherend. The inter-laminar peel and shear stress distributions have been studied in details and are seen to be predominantly three-dimensional in nature. The components of strain energy release rate (SERR) corresponding to the opening, sliding and cross sliding modes of delamination are significantly different at the two fronts of the embedded delamination. The sequential release of multi-point constraint (MPC) finite elements in the vicinity of the delamination fronts enables to simulate the growth of the delamination at either ends. This simulation procedure can be utilized effectively for evaluation of the status of the structural integrity of the bonded joints.

  7. Abnormal accumulation of intermetallic compound at cathode in a SnAg3.0Cu0.5 lap joint during electromigration

    International Nuclear Information System (INIS)

    Li Mingyu; Chang Hong; Pang Xiaochao; Wang Ling; Fu Yonggao

    2011-01-01

    Interfacial reactions in a SnAg 3.0 Cu 0.5 /Cu lap joint for naked and encompassed specimens were investigated contrastively under electric current stressing. After applying a constant direct current at 6.5 A for 144 h, an abnormal accumulation of bulk Cu 6 Sn 5 intermetallic compound was found at the cathode for the naked specimen. But normal polarization phenomenon arose for the encompassed specimen at the same current density for 504 h. The abnormal accumulation phenomenon was explained by the mechanism that thermomigration and stress migration induced by temperature gradient dominated the migration process. A three-dimensional joint simulation model was designed to demonstrate how current crowding and temperature gradient can enhance the local atomic flux.

  8. Dynamic strain distribution measurement and crack detection of an adhesive-bonded single-lap joint under cyclic loading using embedded FBG

    International Nuclear Information System (INIS)

    Ning, Xiaoguang; Murayama, Hideaki; Kageyama, Kazuro; Wada, Daichi; Kanai, Makoto; Ohsawa, Isamu; Igawa, Hirotaka

    2014-01-01

    In this study, the dynamic strain distribution measurement of an adhesive-bonded single-lap joint was carried out in a cyclic load test using a fiber Bragg grating (FBG) sensor embedded into the adhesive/adherend interface along the overlap length direction. Unidirectional carbon fiber reinforced plastic (CFRP) substrates were bonded by epoxy resin to form the joint, and the FBG sensor was embedded into the surface of one substrate during its curing. The measurement was carried out with a sampling rate of 5 Hz by the sensing system, based on the optical frequency domain reflectometry (OFDR) throughout the test. A finite element analysis (FEA) was performed for the measurement evaluation using a three-dimensional model, which included the embedded FBG sensor. The crack detection method, based on the longitudinal strain distribution measurement, was introduced and performed to estimate the cracks that occurred at the adhesive/adherend interface in the test. (paper)

  9. Preservation of ancient impact ages on the R chondrite parent body: 40Ar/39Ar age of hornblende-bearing R chondrite LAP 04840

    Science.gov (United States)

    Righter, Kevin; Cosca, Michael A.; Morgan, Leah

    2016-01-01

    The hornblende- and biotite-bearing R chondrite LAP 04840 is a rare kind of meteorite possibly containing outer solar system water stored during metamorphism or postshock annealing deep within an asteroid. Because little is known regarding its age and origin, we determined 40Ar/39Ar ages on hornblende-rich separates of the meteorite, and obtained plateau ages of 4340(±40) to 4380(±30) Ma. These well-defined plateau ages, coupled with evidence for postshock annealing, indicate this meteorite records an ancient shock event and subsequent annealing. The age of 4340–4380 Ma (or 4.34–4.38 Ga) for this and other previously dated R chondrites is much older than most impact events recorded by ordinary chondrites and points to an ancient event or events that predated the late heavy bombardment that is recorded in so many meteorites and lunar samples.

  10. Bearing Stress at Failure of Double-Lap Hybrid Joints in Woven Fabric Kenaf Fiber Composite Plates under Quasi-static Loading

    Directory of Open Access Journals (Sweden)

    Lee Sim Yee

    2017-01-01

    Full Text Available The present paper is focused on the bearing stress at failure of double-lap woven fabric kenaf fiber reinforced polymer (KFRP hybrid bonded-bolted joints in experimental frameworks. The effects of different normalized plate width (plate width/hole diameter, W/d, lay-up types and bolt loads were incorporated in current study as specified in testing series. Generally, hybrid joint coupons separated within adhesive layer prior to net-tension failure or bearing/net-tension failure. The bearing stress at failure increased as W/d ratio increment, critical W/d is given as four and three in clamped and finger tight condition respectively. Lay-up types present insignificant effect to bearing stress at failure due to low volume fiber fraction in kenaf fiber composites. Combination of thicker and clamped conditions plate demonstrated greater bearing stress than equivalent finger-tight (FT conditions due to higher load transferred from friction, as expected.

  11. Geophysical surveys and velocimetric measures in the Cerreto di Spoleto (Perugia) area, aiming at a seismic microzoning; Indagini geofisiche e misure velocimetriche finalizzate alla microzonazione sismica dell'area di Cerreto di Spoleto (Perugia)

    Energy Technology Data Exchange (ETDEWEB)

    Bongiovanni, G.; Martino, S.; Paciello, A.; Verrubbi, V. [ENEA, Div. Caratterizzazione dell' Ambiente e del Territorio, Centro Ricerche Csaccia, S. Maria di Galeria, Rome (Italy)

    2001-07-01

    Geophysical prospectings and velocimetric measures, aiming at the seismic microzoning of Cerreto di Spoleto area, are presented. Starting from the data obtained by previous geological-geomechanical surveys, seismic-refraction prospectings were carried on in order to obtain a dynamic characterisation and a geometrical description both of soil and rock materials. The velocimetric measures were performed by temporary free-field arrays, recording both environmental noise and small-magnitude seismic events. The analysis of the obtained records is still in progress, in order to evaluate the local seismic wave amplification. [Italian] Vengono illustrate le indagini geofisiche e le misure velocimetriche condotte nell'area di Cerreto di Spoleto (PG) per la microzonazione sismica. In particolare, sulla base dei dati geologici e geomeccanici precedentemente acquisiti, sono state effettuate indagini di sismica a rifrazione che hanno portato alla caratterizzazione dinamica dei litotipi ed alla definizione delle loro geometrie. Le misure velometriche sono state condotte installando array temporanei in free-field per la registrazione di rumore ambientale ed eventi sismici di piccola magnitudo. E' in corso l'elaborazione delle registrazioni ottenute, finalizzata all'analisi degli effetti di amplificazione sismica locale.

  12. William Franke, Sulla verità poetica che è superiore alla Storia: Porfirio e la critica filosofica della letteratura William Franke, On the Poetic Truth that is Higher than History: Porphyry and the Philosophical Interpretation of Literature

    Directory of Open Access Journals (Sweden)

    Laura Lucia Rossi

    2010-06-01

    Full Text Available

    In this article we propose the translation of William Franke’s paper On the Poetic Truth that is Higher than History: Porphyry and the Philosophical Criticism of Literature, in which the American scholar presents the hermeneutic method of the ancient commentators of Homer, with particular reference to the critic practice applied by the Neoplatonic Porphyry in his De Antro Nympharum. With this treatment Franke proposes and hopes for the return to an interpretive method, called philosophical or speculative, also for contemporary criticism.

    In questo articolo è presentata la traduzione del saggio di William Franke Sulla verità poetica che è superiore alla Storia: Porfirio e la critica filosofica della letteratura, in cui lo studioso americano presenta il metodo ermeneutico degli antichi commentatori di Omero, con particolare riferimento alla critica praticata dal neoplatonico Porfirio, proponendo e auspicando il ritorno ad una modalità interpretativa, detta filosofica o speculativa, anche per la critica contemporanea.

  13. Prime osservazioni in tema di rappresentanza sindacale: dal protocollo del 31 maggio 2013 alla sentenza della Corte Costitu­zionale n. 231 del 2013

    Directory of Open Access Journals (Sweden)

    Marina Capobianco

    2013-07-01

    áti­cas divisiones averiguadas en los últimos años entre los sindicatos. El Protocolo se pone en perfecta línea de continuidad con el anterior Acuerdo Interconfederal del 28 junio del 2011, diferenciándose de ello, sin embargo, en algunas partes. Dentro de este escenario, se analiza la reciente pronunciación de la Corte Constitucional sobre la legitimidad constitucional del art. 19 del Estatuto de los Trabajadores hoy, recorriendo las etapas de progresiva afirmación de la nueva orientación jurisprudencial dirigida a encontrar soluciones de compromiso para poner punto final a la añosa cuestión de la representación "irrisorta", en el ámbito del vacío legislativo en materia sindical. Riassunto - L'Autore affronta lo spinoso tema della rappresentanza sindacale alla luce del­la stipulazione della recente Intesa recante indicazioni in tema di misurazione della rappresen­tatività, sottoscritta unitariamente dalle parti sociali per porre fine alle drammatiche divisioni verificatesi negli ultimi anni sul fronte endo-sindacale. Il Protocollo si pone in perfetta linea di continuità con il precedente Accordo Interconfederale del 28 giugno del 2011, differenziando­sene, tuttavia, su alcune parti. Entro tale scenario, si analizza la recente pronuncia della Con­sulta sulla legittimità costituzionale dell'art. 19 dello Statuto dei Lavoratori oggi, ripercorren­dosi le tappe di progressiva affermazione del nuovo orientamento giurisprudenziale volto a trovare soluzioni di compromesso per porre fine alla annosa questione della rappresentanza “irrisorta”, nell'ambito del vuoto legislativo in materia sindacale. Sommario – 1. L'Accordo del 31 maggio 2013 nel quadro dei previgenti accordi interconfe­derali – 2. Le nuove misure di rappresentatività – 3. L'efficacia soggettiva ed i criteri di votazio­ne - 4. La clausola di esigibilità e di tregua sindacale – 5. La portata e gli effetti del nuovo accordo – 6. La recente decisione della Consulta e le "soluzioni" al

  14. Korpikuusen kannon alla : Hahmosuunnittelun anatomia

    OpenAIRE

    Toivola, Laura

    2012-01-01

    Teksti on tutkimus hahmosuunnittelun metodeista ja siitä, mistä muodostuu ja kuinka luodaan ”hyvä” hahmo. Käytännön osiossa muunnetaan sarjakuvastripeissä käytetty hahmo tekijän alter egosta itsenäiseksi 3D-animaatiohahmoksi. Hahmon suunnittelu on jaettu kahteen osaan; hahmon taustan ja henkilöhistorian suunnitteluun sekä hahmon visuaalisen ulkomuodon ja habituksen luomiseen. Tekstissä käsitellään erilaisia näkökulmia, joita voi käyttää hyväkseen hahmoa luodessa ja pohditaan viitekirjal...

  15. Plagiaatorist Saksa minister andis alla

    Index Scriptorium Estoniae

    2011-01-01

    Saksamaa kaitseminister Karl-Theodor zu Guttenberg astus plagiaadiskandaali tõttu tagasi. Karl Theodor zu Guttenberg on veebilehe GutenPlag Wikia andmetel pea sõna-sõnalt ilma viitamata teistelt autoritelt maha kirjutanud viiendiku oma doktoritööst

  16. Pluss ja miinus / Hendrik Alla

    Index Scriptorium Estoniae

    Alla, Hendrik, 1976-

    1998-01-01

    Jõuluteemalistest ja jõuluvanalistest arvutireklaamidest. Halb: MicroLink (idee: MicroLink, teostus: Division) 'Arreteeriti jõuluvana!', Assert (Limit Reklaam) 'Viktor (57), näärivana'. Parem: PCT (Snaiper) 'Sa ju lubasid...'.

  17. Kuidas kirjutada kunstiajalugu? / Anu Allas

    Index Scriptorium Estoniae

    Allas, Anu, 1977-

    2010-01-01

    14. ja 15. mail 2010 Tallinnas toimunud USA Clarki instituudi ja Eesti Kunstiakadeemia Kunstiteaduse Instituudi seminarist "Thinking Art History in East-Central Europe" (Arutlusi Kesk- ja Ida-Euroopa kunstiajaloo teemal)

  18. Micro friction stir lap welding of AISI 430 ferritic stainless steel: a study on the mechanical properties, microstructure, texture and magnetic properties

    Science.gov (United States)

    Mostaan, Hossein; Safari, Mehdi; Bakhtiari, Arash

    2018-04-01

    In this study, the effect of friction stir welding of AISI 430 (X6Cr17, material number 1.4016) ferritic stainless steel is examined. Two thin sheets with dimensions of 0.4 × 50 × 200 mm3 are joined in lap configuration. Optical microscopy and field emission electron microscopy were used in order to microstructural evaluations and fracture analysis, respectively. Tensile test and microhardness measurements are employed in order to study the mechanical behaviors of welds. Also, vibrational sample magnetometry (VSM) is employed for characterizing magnetic properties of welded samples. Texture analysis is carried out in order to clarify the change mechanism of magnetic properties in the welded area. The results show that AISI 430 sheets are successfully joined considering both, the appearance of the welding bead and the strength of the welded joint. It is found that by friction stir welding of AISI 430 sheets, texture components with easy axes magnetization have been replaced by texture components with harder magnetization axes. VSM analysis showed that friction stir welding leads to increase in residual induction (Br) and coercivity (Hc). This increase is attributed to the grain refining due the friction stir welding and formation of texture components with harder axes of magnetizations.

  19. Demand Response Potential for California SubLAPs and Local Capacity Planning Areas: An Addendum to the 2025 California Demand Response Potential Study – Phase 2

    Energy Technology Data Exchange (ETDEWEB)

    Alstone, Peter [Humboldt State Univ., Arcata, CA (United States). Schatz Energy Research Center; Potter, Jennifer [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Piette, Mary Ann [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Schwartz, Peter [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Berger, Michael A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Dunn, Laurel N. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Smith, Sarah J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Sohn, Michael D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Aghajanzadeh, Arian [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Stensson, Sofia [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Szinai, Julia [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-04-01

    The 2025 California Demand Response Potential Study Phase 2 Report1 was released on March 1, 2017, and described a range of pathways for Demand Response (DR) to support a clean, stable, and cost-effective electric grid for California. One of the Report’s key findings was that while there appears to be very low future value for untargeted DR Shed aimed at system-wide peak load conditions, there could be significant value for locally focused Shed resources. Although the dynamics of renewable capacity expansion have reduced the pressure to build new thermal generation in general, there are still transmission-constrained areas of the state where load growth needs to be managed with the addition of new local capacity, which could include DERs and/or DR. This Addendum to the Phase 2 Report presents a breakdown of the expected future “Local Shed” DR potential at a finer geographic resolution than what is available in the original report, with results summarized by SubLAP and Local Capacity Area (LCA).

  20. Proteomic profiling of antibody-inducing immunogens in tumor tissue identifies PSMA1, LAP3, ANXA3, and maspin as colon cancer markers

    Science.gov (United States)

    Yang, Qian; Roehrl, Michael H.; Wang, Julia Y.

    2018-01-01

    We hypothesized that cancer tissue immunogens – antigens capable of inducing specific antibody production in patients – are promising targets for development of precision diagnostics and humoral immunotherapies. We developed an innovative immuno-proteomic strategy and identified new immunogenic markers of colon cancer. Proteins from cancers and matched normal tissues were separated by 2D gel electrophoresis and blotted with serum antibodies from the same patients. Antibody-reactive proteins were sequenced by mass spectrometry and validated by Western blotting and immunohistochemistry. 170 serum antibody-reactive proteins were identified only in cancerous but not matched normal. Among these, proteasome subunit alpha type 1 (PSA1), leucine aminopeptidase 3 (LAP3), annexin A3 (ANXA3), and maspin (serpin B5) were reproducibly found in tissues from three patients. Differential expression patterns were confirmed in samples from eight patients with various stages of colon adenocarcinoma and liver metastases. These tumor-resident proteins and/or their associated serum antibodies may be promising markers for colon cancer screening and early diagnosis. Furthermore, tumor tissue-specific antibodies could potentially be exploited as immunotherapeutic targets against cancer. More generally, proteomic profiling of antibody-inducing cancer-associated immunogens represents a powerful generic method for uncovering the tumor antigen-ome, i.e., the totality of immunogenic tumor-associated proteins. PMID:29423100

  1. The Mental Health Leadership and Advocacy Program (mhLAP): a pioneering response to the neglect of mental health in Anglophone West Africa.

    Science.gov (United States)

    Abdulmalik, Jibril; Fadahunsi, Woye; Kola, Lola; Nwefoh, Emeka; Minas, Harry; Eaton, Julian; Gureje, Oye

    2014-01-27

    Developing countries in Africa and other regions share a similar profile of insufficient human resources for mental health, poor funding, a high unmet need for services and a low official prioritisation of mental health. This situation is worsened by misconceptions about the causes of mental disorders, stigma and discrimination that frequently result in harmful practices against persons with mental illness. Previous explorations of the required response to these challenges have identified the need for strong leadership and consistent advocacy as potential drivers of the desired change. The Mental Health Leadership and Advocacy Program (mhLAP) is a project that aims to provide and enhance the acquisition of skills in mental health leadership, service development, advocacy and policy planning and to build partnerships for action. Launched in 2010 to serve the Anglophone countries of The Gambia, Ghana, Liberia, Nigeria, Sierra Leone, this paper describes the components of the program, the experience gained since its initiation, and the achievements made during the three years of its implementation. These achievements include: 1) the annual training in mental health leadership and advocacy which has graduated 96 participants from 9 different African countries and 2) the establishment of a broad coalition of service user groups, non-governmental organizations, media practitioners and mental health professionals in each participating country to implement concerted mental health advocacy efforts that are focused on country-specific priorities.

  2. Plant-based oral tolerance to hemophilia therapy employs a complex immune regulatory response including LAP+CD4+ T cells.

    Science.gov (United States)

    Wang, Xiaomei; Su, Jin; Sherman, Alexandra; Rogers, Geoffrey L; Liao, Gongxian; Hoffman, Brad E; Leong, Kam W; Terhorst, Cox; Daniell, Henry; Herzog, Roland W

    2015-04-09

    Coagulation factor replacement therapy for the X-linked bleeding disorder hemophilia is severely complicated by antibody ("inhibitor") formation. We previously found that oral delivery to hemophilic mice of cholera toxin B subunit-coagulation factor fusion proteins expressed in chloroplasts of transgenic plants suppressed inhibitor formation directed against factors VIII and IX and anaphylaxis against factor IX (FIX). This observation and the relatively high concentration of antigen in the chloroplasts prompted us to evaluate the underlying tolerance mechanisms. The combination of oral delivery of bioencapsulated FIX and intravenous replacement therapy induced a complex, interleukin-10 (IL-10)-dependent, antigen-specific systemic immune suppression of pathogenic antibody formation (immunoglobulin [Ig] 1/inhibitors, IgE) in hemophilia B mice. Tolerance induction was also successful in preimmune mice but required prolonged oral delivery once replacement therapy was resumed. Orally delivered antigen, initially targeted to epithelial cells, was taken up by dendritic cells throughout the small intestine and additionally by F4/80(+) cells in the duodenum. Consistent with the immunomodulatory responses, frequencies of tolerogenic CD103(+) and plasmacytoid dendritic cells were increased. Ultimately, latency-associated peptide expressing CD4(+) regulatory T cells (CD4(+)CD25(-)LAP(+) cells with upregulated IL-10 and transforming growth factor-β (TGF-β) expression) as well as conventional CD4(+)CD25(+) regulatory T cells systemically suppressed anti-FIX responses. © 2015 by The American Society of Hematology.

  3. Sottoscrizioni autografe nelle più antiche carte del monastero di S. Liberatore alla Maiella. Contributo alla storia del rapporto tra scrittura e alfabetismo in Abruzzo nel secolo X Autograph subscriptions in the oldest cards of the monastery of S. Liberatore of the Maiella. A contribution to the history of the relationship between writing and literacy in Abruzzo in 10th Century

    Directory of Open Access Journals (Sweden)

    Mariano Dell'Omo

    2005-06-01

    Full Text Available

    Il saggio che si propone di contribuire alla storia delle relazioni tra scrittura e alfabetismo in Abruzzo nel secolo X, deriva da una sezione (pp. CXLI-CLXX della “Introduzione storica, paleografica e archivistica” al volume pubblicato dall’autore nel 2003. L’immediato contesto geo-monastico è quello di S. Liberatore alla Maiella, la più grande delle dipendenze di Montecassino in Abruzzo, e una delle prepositure più notevoli tra le circa sessanta che appartennero al monastero cassinese nell’Italia centro-meridionale. L’obiettivo più generale è quello di far conoscere l’intero fondo archivistico di S. Liberatore, sia quello di età medievale con il citato volume, sia quello di età moderna con il successivo, apparso nel 2006. Questa specifica serie dell’Archivio cassinese, gravitante intorno a S. Liberatore ma relativa anche ad altri centri monastici minori di area abruzzese, e che occupa oggi le capsule da XCIX a CIV, racchiude complessivamente 801 documenti.

    Tra questi se ne annoverano alcuni particolarmente noti agli studiosi – specialmente dopo i lavori di Enrico Carusi (1929, 1932 e Herbert Bloch (1986 –, come il “Memoratorium” dell’abate Bertario († 883 e il “Commemoratorium” – inventario testamentario – del preposito maiellese, poi abate di Montecassino Teobaldo († 1035/1037.

    Alcuni hanno riservato interessanti scoperte, come l’attuale caps. XCIX, fasc. I, n. 4, una carta del luglio 936, che racchiude la più antica sottoscrizione autografa (“Ego qui supra Arechisi iudex” di Arechi, giudice della città di Capua, lo stesso che sottoscrisse il celeberrimo placito del 960, prima testimonianza ufficiale di volgare italiano.

    Altri costituiscono un nucleo di documenti omogenei (nn. 7, 8, 9, 10, 12, 13 la cui edizione integrale ha offerto finalmente in modo completo la più antica collezione di contratti agrari di Montecassino (dal 950 al 984, specialmente sotto forma di

  4. Prevalence of comorbidities and baseline characteristics of LAP-BAND AP® subjects in the Helping Evaluate Reduction in Obesity (HERO study.

    Directory of Open Access Journals (Sweden)

    Nancy Dreyer

    Full Text Available OBJECTIVE: To describe the baseline characteristics in patients who chose placement of a LAP-BAND AP® System (LBAP and participated in the Helping Evaluate Reduction in Obesity (HERO Study across regions. PATIENTS AND METHODS: HERO is a five-year, prospective, multicenter, international study of patients with LBAP placement between July 22, 2009 and January 31, 2011. In addition to baseline and peri-surgery clinical data, seven follow up visits are scheduled at 3, 6 and 12 months, and annually through year five. Data collection included family and medical history, clinical outcomes, laboratory data, health-related quality of life (HRQoL, productivity, healthcare resource utilization, and adverse events. RESULTS: LBAP were placed in 1106 enrolled patients; 56.6% from the US, 26.3% from Europe, 7.1% from Canada, and 10.0% from Australia. The majority were female (n = 877 (79.3% with a mean age of 43 years (s.d. = 11.4 and mean body mass index of 45.1 kg/m(2 (s.d. = 6.9. The most common comorbidities were hypertension (HTN (overall  = 42.9% and diabetes (overall 22.2%, with 27% from the US and 14% from Europe. Overall, less than 5% had a history of cardiovascular disease. The prevalence rates of HTN, diabetes and cardiovascular disease were significantly (p<0.001 higher in men than in women across all regions. Overall HRQoL also worsened with increasing BMI. CONCLUSIONS: The HERO study is the first large, multinational and long-term registry with the LBAP. This study will provide real-world outcomes data on LAGB that will help inform patient choice, clinician treatment strategies, and payer reimbursement decisions.

  5. Fusion welding of Fe-added lap joints between AZ31B magnesium alloy and 6061 aluminum alloy by hybrid laser-tungsten inert gas welding technique

    International Nuclear Information System (INIS)

    Qi, Xiao-dong; Liu, Li-ming

    2012-01-01

    Highlights: → Hybrid Laser-TIG fusion welding technique was used for joining Mg to Al alloys. → Laser defocusing amount determined penetration depth inside Al alloy of joints. → The addition of Fe interlayer suppressed Mg-Al intermetallics greatly in joints. → A maximum joint strength with optimum thickness of Fe interlayer was obtained. → Excessive addition of Fe interlayer was adverse for the strength improvement. -- Abstract: AZ31B magnesium alloy and 6061-T6 aluminum alloy were lap joined together with the addition of Fe interlayer by fusion welding of hybrid laser-tungsten inert gas (TIG) technique. The influence of location of laser focal spot (LFS) on joint penetration depth and that of the depth on joint strength were investigated. The results showed that when the LFS was just on the surface of Al plate, the deepest penetration could be obtained, which contributed to the improvement of shear strength of Fe-added joints, but not to the elevation of the strength of Mg/Al direct joints. The addition of Fe interlayer suppressed massive production of Mg-Al intermetallics but produced Fe-Al intermetallics in the fusion zone of the joints, whose micro-hardness was extremely high and was also adverse for the enhancement of joint shear strength. The effect of Fe-interlayer thickness on the joint shear strength was also examined, and the maximum shear strength of Fe-added joint could achieve 100 MPa with 0.13 mm thick Fe interlayer. The fracture modes of 0.07 and 0.13 mm Fe-interlayer-added joints were both quasi-cleavage, while those of direct and 0.22 mm interlayer-added joints were completely cleavage. The theoretical shear strength of the Fe-added joints was also discussed.

  6. Experimental and numerical studies on the issues in laser welding of light-weight alloys in a zero-gap lap joint configuration

    Science.gov (United States)

    Harooni, Masoud

    current study a non-destructive evaluation method based on spectroscopy is proposed to detect the presence of pores in the lap joint of laser welded AZ31B magnesium alloy. The electron temperature that is calculated by the Boltzmann plot method is correlated to the presence of pores in the weld bead. A separate series of experiments was performed to evaluate the effect of an oxide coating layer on the dynamic behavior of the molten pool in the laser welding of an AZ31B magnesium alloy in a zero-gap lap joint configuration. A high speed CCD camera assisted with a green laser as an illumination source was selected to record the weld pool dynamics. Another technique used in this study was two-pass laser welding process to join AZ31B magnesium sheet in a zero-gap, lap-shear configuration. Two groups of samples including one pass laser welding (OPLW) and two pass laser welding (TPLW) were studied. In the two pass laser welding procedure, the first pass is performed by a defocused laser beam on the top of the two overlapped sheets in order to preheat the faying surface prior to laser welding, while the second pass is applied to melt and eventually weld the samples. Tensile and microhardness tests were used to measure the mechanical properties of the laser welded samples. A spectrometer was also used in real-time to correlate pore formation with calculated electron temperature using the Boltzmann plot method. The results of calculated electron temperature confirmed the previous results in earlier chapter. Magnesium and aluminum are two alloys which are used in different industries mainly due to their light weight. The main use of these two alloys is in automotive industry. Since different parts of the automobiles can be manufactured with each of these two alloys, it is essential to evaluate the joining feasibility of dissimilar metals such as aluminum to magnesium. A 4 kW fiber laser is used to join AZ31B magnesium alloy to AA 6014 using an overlap joint configuration. Two

  7. Application of life cycle assessment to production processes of environmentally sustainable concrete, prepared with artificial aggregates; Applicazione della metodologia life cycle assessment alla produzione di conclomerati cementizi di qualita' contenenti aggregati artificiali

    Energy Technology Data Exchange (ETDEWEB)

    Vaccaro, R. [Italrecuperi, Pozzuoli (Italy); Colangelo, F. [Basilicata Univ., Poteza (Italy). Dip. di Ungegneria e Fisica dell' Ambiente; Palumbo, M. [Federico II Univ., Napoli (Italy). Dipartimento di Ingegneria e Fisica dell' Ambiente; Cioffi, R. [Parthenope Univ., Napoli (Italy). Dipartimento per le Tecnologie

    2005-08-01

    This paper is about the application of Life Cycle Assessment (L.C.A.) on environmentally sustainable concrete production processes. The goal of this experimentations is to assess environmental impact and energy demand related to concrete production, by using, in different admixtures, natural and artificial aggregates, belonging from treatments of different kind of industrial wastes characterized by very small particle sizes. Particular attention was concentrated on the utilization of fine fraction since it is difficult to recover in usual fields of recycling (i.e. aggers, crowl spaces, etc.). This study follows the approach from cradle to cradle. This experimentation was conducted in relation to four concrete admixtures produced, one of them containing only natural aggregate, and the other ones obtained by substituting the 10% of aggregate respectively with inert wastes as construction and demolition waste (CeD waste). cement kiln dust (CKD) and marble sludge. For all admixtures six different end-life scenarios have been proposed, one of them considers all materials transported in landfill while the other ones consider a partial transportation on landfill (15%) and a recycle of the 85% of wastes obtained after demolition of structures. [Italian] Il presente lavoro ha come oggetto l'applicazione della metodologia Life Cycle Assessment (L.C.A.) ai processi produttivi di calcestruzzi eco-compatibili. L'obiettivo dello studio e' quello di valutare il carico ambientale ed il consumo energetico associato alla produzione di calcestruzzo impiegando, in differenti miscele, aggregati artificiali provenienti dal trattamento di differenti tipologie di scarti industriali di pezzatura molto piccola. E' stata posta particolare attenzione all'utilizzo della frazione fine in quanto quest'ultima risulta piu' difficilmente recuperabile nei consueti campi d'impiego (es. rienpimento per sottofondi stradali, vespai, etc.). L

  8. A Computer in Your Lap.

    Science.gov (United States)

    Byers, Joseph W.

    1991-01-01

    The most useful feature of laptop computers is portability, as one elementary school principal notes. IBM and Apple are not leaders in laptop technology. Tandy and Toshiba market relatively inexpensive models offering durability, reliable software, and sufficient memory space. (MLH)

  9. Erivajadustega laps tavakooli? / Kaja Plado

    Index Scriptorium Estoniae

    Plado, Kaja

    1997-01-01

    Tartu Õpetajate Seminari üliõpilaste poolt läbi viidud ankeedist, selgitamaks, kui palju on tavakoolis abi vajavaid lapsi, kuidas nad jaotuvad klassiti ja õppeainete kaupa ning missugune on õpetajate hoiak nende lastega töötamiseks

  10. The first lap in QCD

    International Nuclear Information System (INIS)

    Close, F.E.

    1980-07-01

    The idea that quantum chromodynamics is Nature's choice for the theory of quark interactions and that desirable phenomena, such as quark confinement, are consequences of it are considered. The lecture is presented under the headings: (1) Why do we believe that quarks have colour. (2) A rapid summary of the parton model in deep inelastic scattering. (3) Non Abelian theories: the vertices. (4) Hyperfine splitting of hadrons: more evidence for colour. (5) Renormalisation. (6) Alpha(Q 2 ). (7) The renormalisation group equations. (8) QCD, the renormalisation group equation and deep inelastic data. (9) Higher order corrections in QCD. (U.K.)

  11. Laps ja loodus / Patrik Grahn

    Index Scriptorium Estoniae

    Grahn, Patrik

    2009-01-01

    Looduses viibimise ja mängimise tähtsusest lapse arengus. Artiklis tuginetakse uurimustele looduse, parkide ja aedade erinevate omadustega tüüpidest, eelkooliõuede õuemängude kohtadest ning looduspiirkondade tähendusest laste tervisele, motoorikale ja keskendumisvõimele

  12. Professionnalité des enseignants: vers une définition du collectif à partir d'une recherche au Lycée Autogéré de Paris (LAP

    Directory of Open Access Journals (Sweden)

    Maria Papantoniou

    2012-12-01

    Full Text Available Nous proposons de présenter dans cet article une partie des résultats de la recherche que nous avons effectuée au sein du Lycée Autogéré de Paris (LAP. Nos observations sont centrées sur le fonctionnement de ce lycée et ses incidences sur le rapport des élèves à l'école et aux disciplines scolaires. Nous avons été amenée à proposer le concept de Travail d'Institutionnalisation (TDI pour désigner la pratique d'autogestion au LAP qui consiste en un double travail: d'une part, sur les normes internes du lycée et, d'autre part, sur ses rapports aux institutions qui le traversent. Comment ce concept interroge-t-il la "violence" qui surgirait dans l'institution éducative et les pratiques des professionnels censées y répondre?

  13. PO.RA project. An analysis on gas radon concentrations in soil versus fluctuations in the groundwater table; Progetto PO.RA.. Analisi della concentrazione di gas radon nel non saturo in relazione alla soggiacenza della falda freatica

    Energy Technology Data Exchange (ETDEWEB)

    Serentha' , C.; Torretta, M. [Agenzia Regionale per la Protezione dell' Ambiente della Lombardia, Dipartimento di Monza, Monza (Italy)

    2001-09-01

    Man is daily exposed to natural radiation, mainly due to cosmic rays and natural radioactive elements, whose most important radioactive daughters are {sup 222}Rn (radon) and {sup 220}Rn (thoron). Being these ones gaseous, they can spread through the ground, reaching the atmosphere and accumulating in rooms, where their concentrations may be very high. As radon exhalation is strongly connected with the hydrogeological features of the environment, this study tried to find a relationship between fluctuations in the groundwater table and gas radon concentrations in soil, in order to try estimates of indoor radon concentrations. [Italian] L'uomo e' quotidianamente esposto ad una radioattivita' di origine naturale, dovuta principalmente ai raggi cosmici ed alla presenza di alcuni elementi radioattivi naturali, i cui discendenti radioattivi piu' importanti sono il {sup 222}Rn (radon) e il {sup 220}Rn (thoron). Tali elementi, a causa della loro natura gassosa, si possono diffondere attraverso il terreno e raggiungere l'atmosfera sovrastante; cio' puo' provocarne l'accumulo in ambienti chiusi, dando luogo a concentrazioni anche elevate con possibili conseguenze sulla salute. Poiche' l'esalazione del gas radon e' foremente legata alle caratteristiche idrogeologiche dell'ambiente, in questo lavoro si e' cercato di definire una relazione che legasse le variazioni della soggiacenza della falda freatica alle variazioni della concentrazione del gas radon nel non saturo, al fine di verificare se sia possibile effettuare un'attivita' previsionale applicabile ai rilievi di gas radon indoor.

  14. L'Italia di fronte alla mafia

    Directory of Open Access Journals (Sweden)

    Elisabetta Cesqui

    2018-03-01

    Full Text Available La realtà odierna delle mafie è in forte evoluzione e assume fra l’altro forme concrete diverse. Il lavoro compiuto dagli Stati Generali promossi dal Ministero della Giustizia ha messo in luce la complessità dei rapporti tra mafie e società, illuminando le zone di debolezza del sistema legale. Questo viene dunque chiamato oggi a sviluppare strategie di contrasto e di prevenzione sorrette da una nuova consapevolezza del fenomeno mafioso, che dimostra sempre più di non avere confini, né sul piano geografico né sul piano sociale o culturale. Parole chiave: criminalità organizzata, mafie, Stati Generali, strategia, prevenzione, consapevolezza, legalità   Nowadays mafias are seeing a phase of strong expansion, in a variety of different directions and shapes. The work carried out by the General States promoted by the Ministry of Justice has highlighted the complexity of the relations between mafia and society and underlined the weak areas of the existing law. The legal system is now facing the necessity of developing new strategies and tools for tackling and preventing the mafia phenomenon which increasingly proves to have no borders, either geographically or socially or culturally. Keywords: organized crime, mafias, General States , strategy, prevention, awareness, legality

  15. Mimesis: dalla riflessione teoretica alla prassi educativa

    Directory of Open Access Journals (Sweden)

    Gilberto Scaramuzzo

    2013-10-01

    Full Text Available The article reflects on Aristotle’s Poetics, 4.1448 b4-19. It examines how the definition of man as a mimetic animal (b5-9 is underestimated in educational praxis, and then, according to Aristotle, points to mimesis as the core of the understanding/learning processes. Arguing a revaluation of mimesis as necessary to educational praxis, the article presents a project delivered through this principle in a multi-ethnic school context.

  16. An artist and his double / Anu Allas

    Index Scriptorium Estoniae

    Allas, Anu, 1977-

    2010-01-01

    Marko Raadi portreefilmist kunstnik Jaan Toomikust "Toomiku film" (Allfilm, 2008) ning näitlejast, lavastajast ja elukunstnikust Alar Sudakust (kunstnikunimega Elaan) "Isa, Poeg ja Teatri Vaim" (Allfilm, 2009) sarjast "Eesti lood"

  17. Deceptive pictures and revealing sounds / Anu Allas

    Index Scriptorium Estoniae

    Allas, Anu, 1977-

    2009-01-01

    2009. aasta Ars Fennica kunstipreemia pälvinud eesti kunstniku ja fotograafi Mark Raidpere videokunstist, muusika ja heli tähtsast rollist tema videotes (videod "Pühendus/Dedication" (2008), "5 Guards" (2006), "Wailing Woman" (2007), "Majestoso Mystico" (2007), "Vekovka" (2008) jt.)

  18. Allan Allmere: tulevane Meelis Atonen / Henri Allas

    Index Scriptorium Estoniae

    Arras, Henri

    2009-01-01

    Liberalismi Akadeemia juht ja Tallinna reforminoorte esimees Allan Allmere keskendub 2009. aastal Tallinna linnavolikokku kandideerides peamiselt noortele ja nende probleemidele. Noormehe hobiks on väärtpaberiturgudel mängimine ning oma eeskujudena nimetab ta USA majandusteadlast Milton Friedmani ja Meelis Atoneni

  19. Lihtsalt kunst ja kapital / Anu Allas

    Index Scriptorium Estoniae

    Allas, Anu, 1977-

    2007-01-01

    Saksa galeristi ja kollektsionääri Rolf Ricke kogu põhjal koostatud näitusest "Das Kapital - Blue Chips & Masterpieces" Frankfurdi Moodsa Kunsti Muuseumis. Kunstikogumisest ja kunstipoliitikast Lääne-Euroopas

  20. Tehnoloogiakaotus Eestis alla 50 miljoni / Kaja Koovit

    Index Scriptorium Estoniae

    Koovit, Kaja, 1968-

    2000-01-01

    Nokia, Sonera ja Ericssoni aktsiate hinnad on kuuga langenud ligi 30%, millest Eesti investorid on saanud 30 miljonit krooni kahju. Tabel: Lemmikaktsiate hinnad on kuuga langenud 30%. Ilmunud ka: Delovõje Vedomosti 18. okt. lk. 34

  1. Quando i romanzi facevano male alla salute

    Directory of Open Access Journals (Sweden)

    Stefano Calabrese

    2016-07-01

    Full Text Available Come sostengono neuroscienziati e cognitivisti, attualmente le narrazioni finzionali svolgono un ruolo essenziale nell'aiutare gli individui a elaborare schemi predittivi circa la realtà; inoltre, la fruizione immersiva nelle narrazioni attuali costituisce una palestra in cui i lettori indossano empaticamente le emozioni dei personaggi. Questo accade perché oggi il dinamismo del contesto storico-culturale della globalizzazione ha reso necessaria una maggiore abilità nel mind reading e una profonda competenza nelle metarappresentazioni. Al contrario, nel secolo diciannovesimo le narrazioni producevano nei lettori cattive identificazioni perché il contesto storico-culturale non era per così dire all'altezza delle finzioni narrative. Lo dimostra il caso della ricezione normanna di Madame Bovary. As neuroscience and cognitive psychology assert, nowadays fictional narrative holds an essential role helping individuals elaborating predictive schemes of reality; furthemore, immersive fruition of fiction constitutes a mental training in which readers wear characters’ emotions through empathy. This happens because the dynamic historical and cultural context of globalization requires an always more sophisticated ability in mind reading and a strong competence on meta-representations. On the contrary, during 19th Century narrations produced in readers incomplete identifications, due to a context still historically and culturally backward for narrative fiction, as exemplarily demonstrated by Madame Bovary’s Norman reception.

  2. Leedus pandi homoinfo keelu alla / Kaivo Kopli

    Index Scriptorium Estoniae

    Kopli, Kaivo

    2009-01-01

    Leedu parlament kiitis teist korda heaks seaduse "Alaealiste kaitsmisest negatiivse informatsiooni eest" (Law on the Protection of Minors against the Detrimental Effect of Public Information ; Nepilnameciu apsaugos nuo neigiamo viešosios informacijos poveikio). Lisa: Grybauskaite näeb homofoobiat

  3. Teletrasporto dalla fantascienza alla realtà

    CERN Document Server

    Castellani, Leonardo

    2011-01-01

    Chi di noi correndo nell’ansia di un ritardo non ha desiderato per un attimo di teletrasportarsi nel luogo dell’appuntamento? Proprio come facevano i personaggi di Star Trek entrando nella sala teletrasporto dell’ Enterprise e ricomparendo immediatamente in qualche altro punto dell’universo. Forse ci siamo anche chiesti se la scienza e gli sviluppi della tecnologia ci porteranno mai a questo. Gli autori propongono un viaggio nel mondo dei quanti, dove si nascondono possibilità sorprendenti: non solo il teletrasporto di particelle, ma sistemi crittografici a prova della più abile spia, e calcolatori che usano singoli atomi come registri di memoria, capaci di calcoli ritenuti fino a oggi impossibili. I fondamenti della fisica microscopica vengono descritti senza tecnicismi; se ne illustrano applicazioni che, come è successo in passato con il transistor e il laser, trasformeranno radicalmente i nostri calcolatori, le transazioni commerciali e le carte di credito, le comunicazioni, insomma una parte im...

  4. Alla cerca della particella di dio

    CERN Multimedia

    Caprara, Giovanni

    2007-01-01

    "Keep in mind her name, Fabiola Gianotti. She is the head of a team of 1'800 physicists from all over the world, and work in an historic experiment: to product in a laboratory the initial energy of the Big Bang. She said it will be like to discover an unknown flower. And perhaps, the secret of matter." (2 pages)

  5. Elektrooniline raamat iga padja alla / Aavo Kokk

    Index Scriptorium Estoniae

    Kokk, Aavo, 1964-

    2010-01-01

    Autor arutleb, kuidas muudavad uued tehnilised lahendused raamatute lugemise harjumusi ning raamatuturgu. Elektroonilisest raamatust Sony Reader. Avo Kokk juhatab Balti raamatumessi raames toimuvat konverentsi "E-raamat: evolutsioon või revolutsioon"

  6. Nõukogulik Gruusia annab alla / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2003-01-01

    Hääletustulemuste võltsimisest Adzhaarias 2. novembril toimunud parlamendivalimistel. Adzhaaria autonoomne vabariik ei tunnista uut võimu Gruusias. Tagasiastunud presidendi Eduard Shevardnadze lähikond on uuele võimule järele andnud. Lisa: Gruusia

  7. Dai suoni alla lingua in uso

    DEFF Research Database (Denmark)

    Pierucci, Giulia

    Being able to understand and produce the sound system of the target language is a building block in the process of language learning. In spite of this, pronunciation is often neglected in FL/SL curricula and teaching practice. This project’s goal is to contribute to the field of FLT by designing...... on the whole process of FL learning, this project will integrate intensive training in pronunciation with activities aimed at a range of language components, from grammar to comprehension to pragmatic competence, always based on authentic material. The project’s methodology is based on design research...

  8. Davanti alla grande macchina della legge

    Directory of Open Access Journals (Sweden)

    Remo Ceserani

    2012-06-01

    Full Text Available La letteratura e le sue rappresentazioni del mondo della legge. Differenze profonde tra l’amministrazione della giustizia nei paesi eredi del diritto romano e quella nei paesi di tradizione anglosassone. I protagonisti della scena giudiziaria: l’imputato, il procuratore, gli avvocati, i testimoni, il perito di parte, il giudice, la giuria, il pubblico. La macchina della giustizia, i suoi funzionamenti, l’atmosfera delle udienze nelle metafore letterarie. La frequente incomprensione dei suoi meccanismi da parte di imputati e pubblico. Gli esempi di molti testi letterari e filmici, dal Libro di Giobbe ai romanzi di Grisham.

  9. Davanti alla grande macchina della legge

    OpenAIRE

    Remo Ceserani

    2012-01-01

    La letteratura e le sue rappresentazioni del mondo della legge. Differenze profonde tra l’amministrazione della giustizia nei paesi eredi del diritto romano e quella nei paesi di tradizione anglosassone. I protagonisti della scena giudiziaria: l’imputato, il procuratore, gli avvocati, i testimoni, il perito di parte, il giudice, la giuria, il pubblico. La macchina della giustizia, i suoi funzionamenti, l’atmosfera delle udienze nelle metafore letterarie. La frequente incomprensione dei suoi m...

  10. Dalla crisi finanziaria alla crisi reale

    Directory of Open Access Journals (Sweden)

    CARLO D’ADDA

    2010-01-01

    Full Text Available The financial crisis of 2008 is put in relation with two bubbles, financial and housing. Easy credit is at the origin of both bubbles. Risky bonds were issued to mobilize mortgages originated in the housing market, and bad bonds entered a fantastic number of institutional and private portfolios all over the world without any perception of the their risk. Unfortunately, bank credit to speculators was abundant and fed the final growth of the bubbles. When fears started to spread, the fall was immediate and expectations impaired very rapidly. The main aggregate demand components were severely curtailed and production fell as well. This is the crisis of the real economy. Fortunately, as opposed to what happened in 1929, the interventions of central banks and governments have been of an unprecedented size. The bail out of insolvent banks in particular has been providential. The exit from the current crisis, however, will surely be slow.

  11. Põlva poisid teevad filmiga ilma / Tiia Allas

    Index Scriptorium Estoniae

    Allas, Tiia

    2000-01-01

    Põlvas elavad kooliõpilased Christian Kask ja Daniel Müntinen said Theodor Lutsu filmipäevadel parima animafilmi auhinna oma filmiga "UFO" ja kandideerisid lühimängufilmidega "Voitkajaht" ja "Snaiper" peaauhinnale

  12. Filosofare alla fine dei tempi. Riflessioni agambeniane

    Directory of Open Access Journals (Sweden)

    Scotti, Alessandra

    2012-12-01

    Full Text Available This work focuses on the apocalyptic nature of Giorgio Agamben's philosophical works. The dialogue with Agamben is full of references to St. Paul's letters, Kafka's literary works and Benjamin's messianism. This work tries to define the criteria of the kairological time, considered as a section of the chronological time which deactivates the discretionary mechanism, along the same lines as St. Paul's lessons, which reformulate the distinction between Jews / non-Jews. In this diacritic strategy lies the secret of any future philosophy, that is profanation, meant as the abolition of any sacred limit and the return to a human use.

  13. Constitutional osteochondrodysplasias identifiable a birth. A short review on the state of the art in radiodiagnostic in the late 20. century; Le osteocondrodisplasie costituzionali riconoscibili alla nascita. Una breve rassegna sullo studio dell'arte radiodiagnostica sul finire del 20. secolo

    Energy Technology Data Exchange (ETDEWEB)

    Gugliantini, P.; Maragliano, G.; Piscione, M.; Licata, G. [Azienza Ospedaliera San Giovanni - Addolorata, Rome (Italy)

    1999-03-01

    The value of a systematic radiologic analysis in constitutional osteochondrodysplasias remains underestimated by both neonatologists and radiologists. The authors report the clinical experience of the Department of Neonatology and Neonatal Intensive Cure Unit of St. John Hospital in Rome with constitutional osteochondrodysplasias identifiable at birth. The authors justify the relatively high incidence of constitutional osteochondrodysplasias in this study (66% versus an average incidence of 0,076% reported in the world population) on the basis of: a) an increasing number of high-risk newborns in the intensive cure; b) an improvement in our clinical and radiologic diagnostic skill. They conclude that the state of the art of diagnostic of constitutional osteochondrodysplasiasin still based on the first plain X-ray examination performed at birth because of cardiorespiratory and/or abdominal diseases in the newborn. [Italian] L'importanza dell'analisi radiologica sistematica delle osteocondrodisplasie costituzionali e' tutt'ora sottostimata sia dai neonatologi che dai radiologi. Pertanto riferiamo l'esperianza clinico-radiologica di osteocondrodisplasie costituzionali identificabili alla nascita nel Dipartimento di Neonatologia e Terapia Intensiva Neonatale dell'Ospedale San Giovanni di Roma. L'articolo conclude giustificando la relativamente alta incidenza di ostecondrodisplasie costituzionali della casistica in esame (0,66% contro l'incidenza media dei 0,076% riferita alla popolazione mondiale) sulla base di: a) crescente numero di neonati con alto rischio ricoverati nella unita' di terapia intensiva; b) miglioramento delle capacita' diagnostiche, sia cliniche che radiologiche.

  14. Storia del contributo italiano alla viticoltura sudafricana dalle origini alla contemporaneità

    Directory of Open Access Journals (Sweden)

    Claudio Sessa

    2017-07-01

    Full Text Available Italians over time have formed a symbiotic relationship with the plant of the vine, with its fruit, the grape and its product, the wine. Exported in the world the skills and quality craftsmanship, the know-how of useful knowledge to the development of winemaking in any place or region of the world, as in South Africa. The great skill matured over the centuries has been a useful tool, a “business card” with which to enter into society and different national contexts other than through an integration and comparison process which contributed to the evolution and modification of the screws viticulture sector of South African food and costumes. This article aims to reconstruct the South African wine-making history through the analysis of the Italian contribution to the development of the sector itself in a long-term perspective that goes from the XVII century to contemporary deepening episodes neglected and free from scientific-academic discussion.

  15. Alla fine della vita: bioetica e medicina alla ricerca di un confine

    Directory of Open Access Journals (Sweden)

    Barcaro, Rosangela

    2015-09-01

    Full Text Available [At the end of life: bioethics and medicine looking for a boundary]. Bioethics, neuroscience, medicine are contributing to a debate on the definition and criteria of death. This topic is very controversial, and it demonstrates clashing views on the meaning of human life and death. Official medical and legal positions agree upon a biological definition of death as irreversible cessation of integrated functioning of the organism as a whole, and whole-brain criterion to ascertain death. These positions have to face many criticisms: some scholars speak of logical and practical inconsistency, some others of invalid scientific theory about the supreme integrator. In this paper some criticisms are exposed and discussed in order to reconstruct the state of the art in bioethical debate.

  16. Misure alternative alla detenzione e promozione dei diritti tra prossimità e sollecitudine / Mesures alternatives à l’incarcération et promotion des droits entre proximité et sollicitude / Alternative measures to detention and promotion of the rights between proximity and concern

    Directory of Open Access Journals (Sweden)

    Bisi Roberta

    2016-12-01

    Full Text Available I percorsi che portano ad usufruire di misure alternative alla detenzione sollecitano riflessioni circa l’importanza delle relazioni, dei processi ed anche delle modalità di costruzione degli interventi. Pertanto, è oltremodo necessario che, grazie a comparazioni verificate in altri Paesi e il progetto europeo di ricerca al quale è dedicato questo numero della Rivista ne è un esempio, vengano formulate e trasferite sul piano operativo contenuti e proposte che dovranno scaturire ed essere rilevate con iniziative di studio, di ricerche, di verifiche e di sperimentazioni poiché l’esigenza di libertà, che è alla base della detenzione, pone problemi di fondo e ne sollecita soluzioni, trattandosi di beni raramente e adeguatamente recuperabili o ricostruibili in pieno. Les parcours qui conduisent à bénéficier de mesures alternatives à l’incarcération sollicitent des réflexions sur l’importance des relations, des processus, mais aussi sur les modalités d’élaboration des interventions. Par conséquent, grâce aux comparaisons avec d’autres pays, et au projet de recherche européen auquel ce numéro de la « Revue de Criminologie, Victimologie et Sécurité » est consacré, il est plus que nécessaire que les propositions et les suggestions formulées soient mises en ɶuvre. Ces dernières devront être élaborées à partir d’études, de recherches, de vérifications et d’essais puisque l’exigence de la liberté, qui est à la base de l’incarcération, pose des problèmes majeurs et demande des solutions, s’agissant de biens rarement et adéquatement récupérables ou pouvant être pleinement reconquis. The routes leading to benefit from alternative measures to detention encourage to reflect on the importance of those relationships and procedures involved in the development of the relevant required interventions. Thanks to the comparisons made in other countries (and the European research project examined in this

  17. Abortamento na adolescência: da vida à experiência do colo vazio - um estudo qualitativo Abortion in the adolescence: from life to the experience of the empty lap - a qualitative study

    Directory of Open Access Journals (Sweden)

    Leila Maria Vieira

    2010-10-01

    pregnant; living the abortion and remaking of the life plan. From the analyses of the process it was developed the central category: "Abortion on adolescence: from life to the experience of empty lap". The occurrence of abortion in the adolescence causes different feelings and may reach bio psychosocial circles.

  18. Laps vajab veel riigi toetust / Kalev Kotkas

    Index Scriptorium Estoniae

    Kotkas, Kalev, 1960-

    2001-01-01

    Ilmunud ka: Virumaa Teataja, 5. sept. 2001, lk. 7; Meie Maa, 5. sept. 2001, lk. 4; Lääne Elu, 6. sept. 2001. lk. 4; Valgamaalane, 6. sept. 2001, lk. 2; Koit, 6. sept. 2001, lk. 6; Nädaline, 13. sept. 2001, lk. 4; Vooremaa, 20. sept. 2001, lk. 4; Sakala, 26. sept. 2001, lk. 2; Järva Teataja, 27. sept. 2001, lk. 2. Lastega perede toetamisest. Autor: Rahvaerakond Mõõdukad. Parlamendisaadik

  19. Hüperaktiivne laps / Raivo Juurak

    Index Scriptorium Estoniae

    Juurak, Raivo, 1949-

    2001-01-01

    12. mail 2001 arutasid lastepsühhiaatrid ja kooliõpetajad Tallinnas seminaril hüperaktiivsete ja tähelepanupuudulikkusega laste probleemi. Ettekanded pidasid lastepsühhiaatria dotsent Seija Sandberg Helsingi ülikoolist ja lastepsühhiaater Raija Hirsch Stockholmist

  20. Design Concepts. Teacher Edition. Marketing Education LAPs.

    Science.gov (United States)

    Hawley, Jana

    This learning activity packet is designed to help prepare students to acquire a competency: how to use design concepts in preparation for a career in the fashion industry. The unit consists of the competency, four objectives, suggested learning activities, transparency masters, and a pretest/posttest with answer keys. Activities include a…

  1. Textiles. Teacher Edition. Marketing Education LAPs.

    Science.gov (United States)

    Hawley, Jana

    This learning activity packet is designed to help students to acquire a competency: how to use knowledge of textile design to gain expertise in preparation for a career in the fashion industry. The unit consists of the competency, four objectives, suggested learning activities, transparency masters, and a pretest/posttest with answer keys.…

  2. Manufacturing processes 2 grinding, honing, lapping

    CERN Document Server

    Klocke, Fritz

    2009-01-01

    Presents a view of the most common machining and non-machining manufacturing processes. This volume describes the characteristics of abrasive tools, their design and manufacturing, followed by the fundamentals of grinding fluids. It also discusses grinding of different materials (steel, cast iron, hard and brittle materials, nickel and titanium).

  3. Meccanica quantistica relativistica introduzione alla teoria quantistica dei campi

    CERN Document Server

    Maiani, Luciano

    2012-01-01

    Tra gli argomenti trattati: le simmetrie dello spazio-tempo; la particella libera classica; teoria lagrangiana dei campi; quantizzazione dell' equazione di Klein Gordon; quantizzazione del campo elettromagnetico; l'equazione di Dirac; i propagatori dei campi liberi; interazioni; evoluzione nel tempo dei sistemi quantistici; teoria relativistica delle perturbazioni...

  4. ALLA SCOPERTA DEL PACKAGING DESIGN CON IL WEBQUEST

    Directory of Open Access Journals (Sweden)

    Antonietta Gobbis

    2013-01-01

    Full Text Available Il seguente saggio tratta le possibilità di presentazione in Università straniere, dove si insegna l’ItalianoL2, di un aspetto culturale italiano di forte impatto all’estero come il design, attraverso l’innovativa metodologia del webquest. L’iniziale parte teorica descrive il webquest come metodo didattico costruttivista, con particolare riferimento alle sue caratteristiche, parti costituenti e tipologie. Nella seconda parte vengono dati esempi concreti di webquest di breve e lunga durata su due prodotti italiani molto famosi di packaging design, che hanno festeggiato il loro anniversario nel 2012: il Bacio Perugina e il Campari Soda. I risultati positivi di entrambi i progetti intendono mostrare i vantaggi di una didattica centrata sull’alunno basata su attività di problem-solving e strategie di cooperative learning.  Discovering packaging design through webquest The following essay deals about the possibilities to introduce a very successful cultural topic like Italian Design in Universities abroad, where Italian is taught as second foreign language, through the innovative methodology of WebQuests. The theoretical part describes WebQuests as constructivist didactic method with reference to its characteristics, main constituent parts  and typologies. In the second part we give concrete examples of short and long term WebQuests about two very famous packaging design Italian products which celebrated in 2012 their anniversary: BacioPerugina and Campari Soda. The positive results of both projects aim to show the advantages of learner-centered teaching methods based on problem-solving activities and cooperative learning strategies.

  5. Il danno alla persona del lavoratore: il mobbing orizzontale

    Directory of Open Access Journals (Sweden)

    Riccardo Gentile

    2011-12-01

    Full Text Available Sommario:1. Il mobbing tra diritto civile e diritto del lavoro – 2. Il fenomeno mobbing: gli studi iniziali e la definizione – 3. Le concrete condotte integranti fattispecie di mobbing – 4. Onere della prova – 5. Il mobbing orizzontale – 6. L’elemento soggettivo di colpevolezza del da­tore di lavoro nella responsabilità ex art. 2087 c.c. per mobbing orizzontale

  6. Galeriid - mälestusi tegelikkusest / Anu Allas

    Index Scriptorium Estoniae

    Allas, Anu, 1977-

    2005-01-01

    August Künnapu näitus "Ledoux' ja Boullee tagasitulek" Tallinna Linnagaleriis kuni 13. III; Karl Nageli näitus "Kodumaa tütar kutsub!" (portreteeritud limonovlasi) Hobusepea galeriis kuni 14. III; Maksim Gorki/Rainer Sarneti etendus "Ema" Von Krahli teatris; Leo Expressi turvafirma reklaamplakat bussiootepaviljonides/ajalehtedes "Kas sinu kodu on kindlus?/Oled väsinud kauplemast?"

  7. Proteste ed emancipazione alla frontiera europea. Il caso di Lampedusa

    Directory of Open Access Journals (Sweden)

    Annalisa Lendaro

    Full Text Available Riassunto Questo articolo si propone di approfondire a livello teorico i legami tra proteste ed emancipazione dei migranti senza status legale, che si trovano in situazione di detenzione amministrativa sull’isola italiana di Lampedusa. Il presente contributo mette in evidenza il fatto che l’agency dei migranti, seppur privi di libertà e di uno status legale, è determinante per sbloccare una situazione di crisi in un contesto simile allo stato di eccezione descritto da Agamben. Più precisamente, la protesta dei migranti di Lampedusa mostra in che modo la sospensione dello stato di diritto apra degli spiragli per, non solo denunciare l’ingiustizia di alcune norme, ma anche per agire.

  8. USA dollar langes eile alla 12 krooni / Andris Feldmanis

    Index Scriptorium Estoniae

    Feldmanis, Andris, 1982-

    2004-01-01

    Odavast dollarist kaotavad Eesti ettevõtjatest dollaritsooni eksportijad, võidavad importijad. Skeem: Dollari kurss tagasi 90ndate aastate keskpaiga tasemel. Vt. samas: Tõnis Oja. Ameerikale nõrk dollar meeldib

  9. Le Cascine di Firenze: dall’Isola alla tramvia

    Directory of Open Access Journals (Sweden)

    Leonella Pecchioli

    2015-11-01

    Full Text Available When Alessandro de’ Medici, Duke of the Florentine Republic, he recognized the possibility of creating a Royal Estate destined for his own use and enjoyment for agriculture and hunting, and ordered purchase of this vast area on the right bank of the Arno River. The area was outside the city walls, isolated by a dense network of canals, streams and ponds, and characterized by thick, spontaneous, riparian woodlands. Thus, in 1531 the first nucleus of the “Tenuta dell’isola” (Island Estate was born. Today, it is the largest public park in Florence, with a total of 122 Ha, including the various sports instalments, roads, avenues and squares which alternate with large woodland areas. In 1985 an inventory was taken of the entire arboreal and shrubby vegetation of the park from a pathological, forestry and botanical point of view, following an agreement between the Municipality of Florence and the University of Florence. Based on the material and information gathered from the study, it is possible to outline a rather broad picture of the vegetative situation which can then be used to predict evolutionary trends.  

  10. Põlvas näeb Ove Mustingu filmi / Tiia Allas

    Index Scriptorium Estoniae

    Allas, Tiia

    2006-01-01

    8. jaan. linastub Põlva kultuurikeskuses lühimängufilm "Vanameeste paradiis" : stsenaristid Ove Musting (ka idee autor), Urmas Lennuk : režissöör Ove Musting : operaator Mait Mäekivi : helilooja Arian Levin : kunstnik Eva-Marina Gramanovski : näitlejad Tõnu Aav, Aleksander Eelmaa, Tõnu Oja, Ants Ander, Henry Kõrvits : Downtown Pictures 2005

  11. Vanast Palace'ist alles alla viiendiku / Peeter Raidla

    Index Scriptorium Estoniae

    Raidla, Peeter, 1955-

    2004-01-01

    Tallinna ringkonnakohtu tellimusel valminud mahukas ekspertiis annab aluse hotelli tagastamiseotsuse tühistamiseks. Kohtumäärusega on peatatud ka Tallinna linnavalitsuse 11. veebruari korraldus tühistada hotelli kasutusluba. Lisa: Hotell Palace ehitustööd

  12. Dalla crisi finanziaria alla crisi reale. ( Financial and real crisis

    Directory of Open Access Journals (Sweden)

    Carlo D'Adda

    2010-03-01

    Full Text Available  The financial crisis of 2008 is put in relation with two bubbles, financial and housing. Easy credit is at the origin of both bubbles. Risky bonds were issued to mobilize mortgages originated in the housing market, and bad bonds entered a fantastic number of institutional and private portfolios all over the world without any perception of the their risk. Unfortunately, bank credit to speculators was abundant and fed the final growth of the bubbles. When fears started to spread, the fall was immediate and expectations impaired very rapidly. The main aggregate demand components were severely curtailed and production fell as well. This is the crisis of the real economy. Fortunately, as opposed to what happened in 1929, the interventions of central banks and governments have been of an unprecedented size. The bail out of insolvent banks in particular has been providential. The exit from the current crisis, however, will surely be slow.  JEL: E44, G01, G10

  13. Savisaar jäi alla Savisaarele / Andres Ammas

    Index Scriptorium Estoniae

    Ammas, Andres, 1962-2018

    2001-01-01

    Välissuhtlus on olnud Savisaare ja Keskerakonna Achilleuse kand algusest peale. Savisaar pidurdab Keskerakonna arengut. Autor: Isamaaliit. Ilmunud ka: Lääne Elu, 15. veebr. 2001, lk. 4; Hiiu Leht, 16. veebr. 2001, lk. 2; Vooremaa, 17. veebr. 2001, lk. 4; Nädaline, 17. veebr. 2001, lk. 2; Koit, 17. veebr. 2001, lk. 6; Võrumaa Teataja, 17. veebr. 2001, lk. 2; Järva Teataja, 20. veebr. 2001, lk. 2

  14. Alice Kask : Maalid ja joonistused = Paintings and drawings / Anu Allas

    Index Scriptorium Estoniae

    Allas, Anu, 1977-

    2007-01-01

    Maalikunstnik Alice Kase loomingust, mis on pälvinud usalduse tänu oma suveräänsusele, süvenemisele ja tõsidusele. Tema tööde jõud seisneb teose ja füüsilise objekti lahutamatuses, iga nüanss maali pinnal sünnib kuju võtnud materjalist enesest. Tema maalid on väga avatud, kohati isegi ohtlikult avatud kõikvõimalikele tõlgendusviisidele, neis on tasakaalustatud segu ilust, täiuselubadusest, hirmutavusest ning kaosest

  15. Meccanica è vita. Da Calvino alla robotica evolutiva

    Directory of Open Access Journals (Sweden)

    Cristian Fuschetto

    2014-06-01

    Full Text Available Often the scientific innovations are better explained by literature than scientific essay. In the stories of writers they acquire an identity otherwise so forced to remain contradictory. This was the case of Italo Calvino and Primo Levi about “thinking machines” arrived on stage of the History of the late 20th century. In another perspective, this was also the case of another unusual observer of Cybernetics: Charles Darwin.

  16. Más alla del concepto: desarrollo sostenible

    OpenAIRE

    Benavides López, Laura

    2013-01-01

    El artículo tiene la finalidad de promover la reflexión con respecto al desarrollo sostenible, como un marco de referencia para el educador, que le permita comprender la Década de la Educación para el Desarrollo Sostenible y la Declaratoria Paz con Naturaleza.  La autora describe y reflexiona sobre el concepto, desde una perspectiva basada en la alteridad; por lo tanto, parte de una posición ética donde se potencializa a la persona para que sea constructora del desarrollo sostenible que requi...

  17. Strengthening S&T journalism: Musa Fadl Alla Elkheir (Sudan ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2010-12-10

    Dec 10, 2010 ... ... that matched 16 seasoned science journalists from Africa, America, Europe, and the Middle East with 60 of their less-experienced peers from 35 African and Middle Eastern ... CASE STUDY: Egypt — Privatization alone is not enough ... CASE STUDY: Jordan — Dealing with the water deficit in Jordan.

  18. Sulle sponde del Mediterraneo alla ricerca dell’amore perduto

    DEFF Research Database (Denmark)

    Chemi, Tatiana

    2002-01-01

    Review to the Odin Teatret’s last performance, Sale, from a short story of the Italian novelist Antonio Tabucchi. A melancholic and self-ironic love story.......Review to the Odin Teatret’s last performance, Sale, from a short story of the Italian novelist Antonio Tabucchi. A melancholic and self-ironic love story....

  19. Duši alla sauna / Margit Aedla

    Index Scriptorium Estoniae

    Aedla, Margit, 1970-

    2007-01-01

    Duraviti multifunktsionaalne värviline duširuum. Electroluxi Design Lab'07 konkursi finalisti Joao Diego Schimansky Fog Shower (ududuš). Väiksematesse kodudesse sobiv Muoto mobiilne aurusaunatool Muoto-Steam Deluxe

  20. Uus tulumaksuseadus teel kohtuhaamri alla / Sten-Aleks Pihlak

    Index Scriptorium Estoniae

    Pihlak, Sten-Aleks

    2007-01-01

    Uuest tulumaksuseaduse eelnõust. Lisatud: Rahandusminister Ivari Padar: eesmärk pole komisjoni "ära petta" ; KPMG Baltics ASi maksu- ja juriidilise osakonna juhataja Joel Zernaski ja peaminister Andrsu Ansipi kommentaarid ; Euroopa Komisjon oma nõudmistest ei tagane

  1. Terroristlik vundament paisati maa alla koobastesse / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2006-01-01

    Terrorirünnak USA-s 2001. aasta 11. septembril sai alguseks terroristide vastasele sõjale. Kolm päeva pärast rünnakuid olid tuvastatud kaaperdatud lennukites viibinud isikud, keda arvati terroristideks. Vt. samas: Esiterroristi staarilend - bin Laden tunnistas üles; 1. vaatus - Kabul; 2. vaatus - Iraak; 3. vaatus - Iisrael ja naabrid; 4. vaatus - Guantanamo; Terroristide sõnum levib, kuid kaotab ka toetajaid

  2. Voyeuristi alla finestra: Peeping Tom, dalla leggenda al cinema

    Directory of Open Access Journals (Sweden)

    Laura Staiano

    2015-01-01

    Full Text Available This essay deals with voyeuristic attitudes and ʹscopic powerʹ, i.e. the power to gaze at forbidden things and people without being seen. Indeed, its object par excellence coincides with female nakedness, while its subject is an invisible masculinity, which takes delight in looking. The paper is based on a study of the Anglo-Saxon legend of Lady Godiva and it is strictly connected with the subject of my dissertation in progress – metaphorical and physical blindness in 18th century French literature (since several voyeurs got blind because of their instincts and desires. Lady Godiva’s voyeur, called Peeping Tom, is struck blind for having looked out of his window and seen the noblewoman riding naked. This legend has inspired many artists in different fields, and nowadays its heroine is very famous and venerated. In particular, this essay focuses on the relation between this legend and compulsive looking (or scopophilia in two renowned films, Rear Window by Alfred Hitchcock, and Peeping Tom by Michael Powell.

  3. Introduzione alla meccanica razionale elementi di teoria con esercizi

    CERN Document Server

    Biscari, Paolo

    2016-01-01

    Il libro mira a fornire le basi di Meccanica Razionale, corredando l'esposizione teorica con un alto numero di esempi ed esercizi, di tutti i quali si fornisce la soluzione.  Il testo è particolarmente indicato per i corsi di breve o media durata, e può servire da appoggio a corsi che si sviluppino al secondo, o anche al primo anno del corso di studi universitario.

  4. Raffermir le journalisme scientifique: Musa Fadl Alla Elkheir (Soudan)

    International Development Research Centre (IDRC) Digital Library (Canada)

    C'est ainsi que j'en suis venu à penser qu'au lieu de me contenter d'exercer la médecine, je pourrais aussi contribuer à faire connaître la science au grand public. ... À l'époque, j'ai lancé, avec d'autres médecins et journalistes, un réseau en ligne pour favoriser l'échange d'idées, d'opinions et d'information. Un de ces ...

  5. Nel tunnel alla ricerca di una nuova fisica

    CERN Multimedia

    Durante, Elisabetta

    2003-01-01

    The Large Hadron Collider is at the top of world-wide science for particle physics. It promises to open the road to a new knowledge of the universe and its nature. Luciano Maiani and Robert Aymar, actual and future Director Generals of CERN, explain the aims of this most powerful instrument, the difficulties and the industrial repercussions, among which will be the "Grid", that will change the telecommunications (4 pages)

  6. Muutused transiidis panid uusi lahendusi otsima / Roger Allas

    Index Scriptorium Estoniae

    Allas, Roger

    2008-01-01

    Transiidikonverentsil Transestonia tehti kokkuvõte 2007. aasta transiidimahtudest ja otsiti lahendusi tulevikuks. Vt. samas: Tanel Raig. Juhtparteid vaatavad transiidi arendamisel eri suundades; Isamaa ja Res Publica Liidu kommentaar transiidi ja konteinerterminali rajamise kohta

  7. Roheline logistika seisab mõtteviisi taga / Roger Allas

    Index Scriptorium Estoniae

    Allas, Roger

    2008-01-01

    Ülevaade Tallinna Tehnikakõrgkooli 3. kursuse logistikaüliõpilaste poolt korraldatud 9. logistikaseminarist "Go Green", kus toodi välja kitsaskohad, mis takistavad Eesti ettevõtteid keskkonnasõbralikuks muutumast. Lisa: Taust; Tasub teada; Number

  8. Dal calore all'entropia una introduzione alla termodinamica

    CERN Document Server

    Vicentini Missoni, Matilde

    1992-01-01

    Panta rei : processi ed equilibrio ; l'universo termodinamico : l'aspetto processuale ; il punto di vista dei processi come bilancio tra proprietà dell'equilibrio ; il fluire dell'energia ; automobili, frigoriferi e pompe di calore : informazioni tecnologiche ; e allora ? l'entropia ; la termostatica come teoria assiomatica ; la termodinamica dei processi.

  9. Un approccio “sociale” e ontologico alla catalogazione

    Directory of Open Access Journals (Sweden)

    Oreste Signore

    2011-12-01

    Full Text Available ItLa catalogazione è basata sulla conoscenza e sulla comprensione dei legami interdisciplinari tra gli elementi informativi. L’avvento del Web ha modificato profondamente i meccanismi di accesso all’informazione, mentre Web 2.0 e Semantic Web sono due evoluzioni del Web che stanno rivoluzionando i canoni di gestione del patrimonio informativo. Il primo spostando l’accento sul contributo portato dagli utenti, il secondo enfatizzando il ruolo dei dati e dell’interconnessione tra fonti diverse di conoscenza. Il web ha fatto prestare maggiore attenzione all’interoperabilità semantica e ha portato all’adozione di schemi comuni di metadati, mentre il Web 2.0 ha spostato l’accento sull’aspetto “sociale” e sulle folksonomy. Entrambi questi approcci presentano delle limitazioni intrinseche, che vengono superate dall’adesione a principi del Semantic Web e quindi all’adozione di un approccio ontologico, con il superamento della catalogazione centrata sull’oggetto. È possibile coniugare i vantaggi dell’approccio “sociale” (partecipazione degli utenti, ampliamento delle fonti di informazione con quelli puramente ontologici (formalizzazione e condivisione della conoscenza, possibilità di dedurre nuova conoscenza mediante un’opportuna opera di mapping della scheda catalografica e l’implementazione di ambienti sociali che utilizzino le tecnologie del Semantic Web. Un’esperienza in merito è stata condotta in un progetto.EnKnowledge and linking among several disciplines are the basis of cataloguing. The Web has been a revolution in accessing information, while Web 2.0 and Semantic Web are two evolutions of the web which are changing the ways of managing information. Web 2.0 puts much emphasis on user generated content (UGC, and Semantic Web emphasizes the role of data and their linking among different knowledge bases. The web leaded to greater attention paid to the semantic interoperability, with the adoption of common metadata schemes, and Web 2.0 is characterized by the importance of the “social” aspect and folksonomies. However both the approaches show several drawbacks. Conforming to the Semantic Web principles, with the implied adoption of an ontological approach, is a way to overcome them and the item-centric traditional approach to cataloguing. It is possible to combine the advantages coming from a “social” approach (user participation, higher number of information sources with those coming from an ontological approach (representing, exporting and sharing knowledge, to infer new knowledge. This goal can be achieved through a mapping of catalog cards into ontology and the implementation of social environments based on Semantic Web technologies. A project has been a test bed.

  10. Gilbert ja George lasevad oma kunstiteose alla laadida

    Index Scriptorium Estoniae

    2007-01-01

    9.05.2007 öösel on kõigil soovijail võimalik tasuta interneti vahendusel omandada Londonis tegutseva kunstnikepaari Gilbert & George (Gilbert Proesch ja George Passmore) teos "Planed". Aadressid: www.bbc.co.uk/imagine ja www.guardian.co.uk/art

  11. Alla kukkunud lennukiga on reisinud ka Eesti president / Kristi Leppik

    Index Scriptorium Estoniae

    Leppik, Kristi

    2010-01-01

    Smolenski lähedal Venemaal 10. aprillil 2010 toimunud lennuõnnetusest, milles hukkus Poola president Lech Kaszynski, tema abikaasa Maria ja rohkearvuline kõrgetasemeline Poola ametlik delegatsioon. Sama lennukiga TU-157 lendasid Poola president L. Kaczynski, Leedu president Valdas Adamkus, Eesti president Toomas Hendrik Ilves ja Läti välisminister Maris Riekstinsh 12. augustil 2008 toetusvisiidile Gruusiasse

  12. L'Universo alla ricerca delle sue origini

    CERN Document Server

    Picasso, Emilio

    2000-01-01

    Sommario : La Cosmologia è una disciplina storica e come avviene per la storia più si allontana dalla nostra epoca il periodo che vogliamo studiare più rari si fanno i documenti e più difficile è l'interpretazione. Il grande anello di collisione elettrone-positrone, il LEP, permette ai fisici di risalire indietro nel tempo e di studiare i fenomeni che sono avvenuti circa un decimo di miliardesimo dopo il Big Bang. In questo senso limitato il LEP è una finestra sul tempo. In questa conferenza sono brevemente presentati gli argomenti di cosmologia e le costruzione del LEP è descritta in dettaglio.

  13. 2133-IJBCS-Article-ALLA-N'NAN Oulo

    African Journals Online (AJOL)

    admin

    bombardement de particules enrobées d'ADN. Wilmar et al. (1968) ont été les premiers à montrer à partir d'hypocotyle d'Asparagus officinalis que la capacité de régénération de plantes à partir des suspensions cellulaires est fonction du temps de culture de celles-ci. Depuis ces travaux, de nombreuses études ...

  14. Avatud ja suletud Ida-Euroopa / Anu Allas

    Index Scriptorium Estoniae

    Allas, Anu, 1977-

    2009-01-01

    Näitus "Me näeme teid. Foksali galerii tegevus 1966-1989" Kumu Kunstimuuseumis 20. septembrini. Kuraator Karolina Łabowicz-Dymanus. Kujundaja Jaanus Samma. Lääne ja endise Ida-bloki riikide kunst on eksponeeritud kõrvuti

  15. Kõik failid on juba alla laetud! / Eve Arpo

    Index Scriptorium Estoniae

    Arpo, Eve

    2008-01-01

    Berliini iga-aastasest kunsti- ja digitaalkultuuri festivalist "Transmediale" alapealkirjaga "Conspire...", kus käsitleti privaatsuse kadumist, info vaba levikut, hirmu, kopeeritavust, unikaalsust. Võitis ameeriklaste Julia Meltzeri ja David Thorne video "Not a Matter of If but When". Raivo Kelomehe kommentaarid

  16. Approccio dal basso, servizi alla persona e memorie interculturali

    Directory of Open Access Journals (Sweden)

    Orazio Maria Valastro

    2003-06-01

    Full Text Available Valorizzare le memorie dei migranti risponde ad una precisa esigenza di riconoscimento, nella storia collettiva e nello spazio politico nazionale, della memoria interculturale di intere collettività ... Queste condizioni implicano l'esigenza del riconoscimento della memoria dei migranti traducendosi in uno stimolo per lo sviluppo di nuove politiche sociali e culturali e di nuovi interventi focalizzati su questo stesso riconoscimento che interessa direttamente anche gli operatori sociali e culturali delle amministrazioni pubbliche e del terzo settore.

  17. Jalakäijad aetakse ju alla / Leo Kunnas

    Index Scriptorium Estoniae

    Kunnas, Leo, 1967-

    2009-01-01

    Autori sõnul on ainus argument, millega idanaabri sõjalist juhtkonda veenda, sõjaaja relvajõud. Selleks on vaja tõestada, et suudame need vajaduse korral mobiliseerida, seda aga on võimalik teha suurõppuste korraldamisega

  18. Contributo alla conoscenza della flora lichenica epifitica dell'Umbria

    OpenAIRE

    Ravera, Sonia

    2017-01-01

    CONTRIBUTION TO THE EPIPHYTIC LICHEN FLORA OF UMBRIA (C. ITALY). 47 species of epiphytic lichens are reported as additions to the poorly known lichen flora of Umbria. The ecology and distribution of selected species are discussed.

  19. Moodne aeg käib alla / Valner Valme

    Index Scriptorium Estoniae

    Valme, Valner, 1970-

    2008-01-01

    Arvustus: Beigbeder, Frédéric. Armastus kestab kolm aastat : romaan / prantsuse keelest tõlkinud Anti Saar. Tallinn : Varrak, 2008 ; Cusk, Rachel. Arlington Park / tõlkinud Kersti Unt. Tallinn : Varrak, 2007

  20. Kodune energiakulu kontrolli alla / Leo Backman, Heigo Ensling

    Index Scriptorium Estoniae

    Backman, Leo

    2012-01-01

    Energiakulumõõturite test: Axxel HH-549, Efergy e2 (juhtmevaba mõõtur), Electric EMT707CTL, Electronic PM 498, Electronic UPM DEM1379, Energy Meter LX-0805, Eco Line EM235, Energy Saving Meter HH-549, Art.35-617 (multifunktsionaalne mõõtur), EMT7110/EMR7370 (juhtmevaba mõõtur)

  1. Kosmiline eksimus : Vene kapsel kukkus alla vales kohas / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2008-01-01

    Vene kosmoseaparaat laskus Kasahstanis kavandatud kohast 420 kilomeetri kaugusele, kuid korealasest teadlane Yi So-yeon, ameeriklasest astronaut Peggy A. Whitson ja venelasest pardainsener Juri Malantshenko pääsesid eluga

  2. Más alla del concepto: desarrollo sostenible

    Directory of Open Access Journals (Sweden)

    Laura Benavides López

    2013-05-01

    Full Text Available El artículo tiene la finalidad de promover la reflexión con respecto al desarrollo sostenible, como un marco de referencia para el educador, que le permita comprender la Década de la Educación para el Desarrollo Sostenible y la Declaratoria Paz con Naturaleza.  La autora describe y reflexiona sobre el concepto, desde una perspectiva basada en la alteridad; por lo tanto, parte de una posición ética donde se potencializa a la persona para que sea constructora del desarrollo sostenible que requiere el país, donde la educación, la justicia social y la democracia conforman la plataforma para el logro de este. Se señalan aspectos fundamentales, como cuál fue el origen de desarrollo sostenible y como está idea se fue encuadrando dentro de una nueva ética centrada en la gente y para la gente. Se parte de que el desarrollo sostenible es un proceso de cambio y de transición hacia nuevas formas de producir, de consumir, pero también hacia nuevas formas de ser.  Es un proceso multidimensional y complejo, que debe caracterizarse por su innovación, creatividad y apertura. Sin embargo, la dependencia de la política nacional e internacional de la economía micro y macro, de la cultura regional y global, hacen que el concepto se torne difícil de visualizar como un proceso autóctono y que obedezca a las necesidades reales de las personas y comunidades de un país.

  3. Järvi plaanib laulukaare alla hiigelteost / Janar Ala

    Index Scriptorium Estoniae

    Ala, Janar, 1979-

    2009-01-01

    ERSO kunstilise juhi ja peadirigendi kohale asuva dirigendi tulevikuplaanidest, sealhulgas G. Mahleri 8. sümfoonia ettekandmisest 2011. aastal Tallinna lauluväljakul Noorte laulu- ja tantsupeo eelõhtul

  4. Anche una nave alla fonda viaggia... - Anchored ships also travel...

    Directory of Open Access Journals (Sweden)

    Antonio Luigi Palmisano

    2011-09-01

    Full Text Available When travelling, reflections and considerations – more or less structured – are about being “elsewhere”. The subject finds himself physically, socially and politically in this “elsewhere” as an Ego and finds or maybe finds again another Ego, other Ego each of them being still the subject’s own but different from the previous. The structure of travelling is transition and the transitive structure of the Ego also comes to the fore. It is anyway a transition which stimulates reflections, a transition which complicates the Ego. Travelling is therefore the art of complicating the everyday life in order to reach the unexpected. Just as philosophy. But the relation between travelling and philosophy is still deeper: travelling is the praxis of philosophy. The encounter with the “Other” becomes an opportunity to communicate between Seienden which constitute themselves as such actually through the encounter. It is an encounter between men which does not exclude the encounter with Divinity.

  5. Blog.tr.ee ei anna alla / Raigo Neudorf

    Index Scriptorium Estoniae

    Neudorf, Raigo

    2007-01-01

    Veebikeskkonna blog.tr.ee arengust ja majandamisest räägivad keskkonna looja Andris Reinmann ja firma OÜ Tr.ee osaniku Mobi Solutions'i esindaja Rain Rannu. Vt. samas: Mis on blog.tr.ee; Kaljundi: blog.tr.ee on hobiprojekt. Kommenteerib nagi.ee juhataja Jüri Kaljundi. Lisatud joonis: Blog.tr.ee unikaalsete külastajate arv nädalas

  6. Alla scoperta di TV-Glad prima emittente per disabili

    DEFF Research Database (Denmark)

    Chemi, Tatiana

    2006-01-01

    the moving story of the first tv-channel for and made by collaborators with handicaps. The Danish broadcast, which is quickly expanding globally, exporting its unique example of tolerance, fantasy and hard work....

  7. Nõukogude absurd : 1960. aastate eesti kunst eksistentsialismi taustal / Anu Allas

    Index Scriptorium Estoniae

    Allas, Anu, 1977-

    2010-01-01

    Vaadeldakse eksistentsialismi kui üht võimalikku tausta 1960-ndate eesti kunstis, eksistentsialismi ja absurdi suhet ning esilekerkimiste rütmi läbi tolle aja noorte kunstnike korraldatud happening'ide, ka arutelusid kunsti filosoofilisuse, kunstilise kujundi ja inimese kujutamise ning kunstniku rolli üle

  8. Kinnisvara pakkumishinda saab oluliselt alla kaubelda / Andres Hall

    Index Scriptorium Estoniae

    Hall, Andres

    2005-01-01

    Ilmunud ka: Molodjozh Estonii : Nedvizhimost 26. jaan. lk. 1, Delovõje Vedomosti 16. märts lk. 16. . Kinnisvara pakkumishinnad sisaldavad olulisel määral "õhku", mida ostjal on võimalik hinnast maha kaubelda

  9. Pakistan andis Osama bin Ladeni jahtimisel alla / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2004-01-01

    Pakistani president Pervez Musharrafi sõnul on Osama bin Ladeni otsingud Lõuna-Waziristanis tulemusteta. Edaspidi keskendutakse otsingutel Põhja-Waziristani, oletatakse, et bin Laden võib olla ka Tora Bora koobastikus. Lisa: USA hambutu luureteenistus

  10. Il contrasto alla pedopornografia online: esperienze italiane e francesi a confronto / La lutte contre la pédopornographie en ligne : expériences italiennes et françaises comparées / Fighting against online child pornography: a comparison between Italian and French experiences

    Directory of Open Access Journals (Sweden)

    Macilotti Giorgia

    2011-04-01

    exploitation sexuelle des mineurs liée à la dimension virtuelle. Una delle realtà criminali che ha maggiormente fruito delle innovazioni introdotte dalla “società dell’Informazione” è, senza dubbio, quella dell’abuso sessuale sui minori. Tra le differenti forme di abuso sessuale sui minori, si è scelto di affrontare il fenomeno della pedopornografia online in ragione del preoccupante diffondersi di questa forma di criminalità che, grazie all’implementazione delle tecnologie dell’informazione, ha assunto caratteri nuovi, per alcuni versi difformi dai “tradizionali” profili della pedofilia, che sollevano interrogativi e nuove sfide sia sul versante della repressione di queste condotte illecite, sia sul piano della prevenzione. Nell'ambito di questo contributo, saranno esaminate in particolare le politiche penali elaborate in due diverse realtà nazionali, l'Italia e la Francia, a partire da differenti punti di vista e ponendo particolare attenzione agli strumenti, normativi ed operativi, introdotti per reprimere lo sfruttamento sessuale dei minori legato alla dimensione virtuale.

  11. Dal divario Nord-Sud alla convergenza: il modelo dell'intervento straordinario a l'azione della Cassa per in Mezzogiorno, durante e oltre la golden age = From the North-South gap to the convergence: The model of the extraordinary intervention and the...

    Directory of Open Access Journals (Sweden)

    Amedeo Lepore

    2012-07-01

    delle aree del Paese che già possedevano un’armatura industriale, ma si ottenne, contemporaneamente, il risultato, per nulla scontato, di una modernizzazione della struttura economica del Mezzogiorno –attraverso la politica delle opere pubbliche, prima, e dell’industrializzazione vera e propria, poi– nonché, di un recupero del divario accumulato con le regioni settentrionali. In questo modo, l’intervento straordinario, indirizzato verso obiettivi macroeconomici e guidato da una tecnostruttura come quella della Cassa, al tempo stesso autonoma e reattiva alle scelte strategiche del governo, si dimostrò lo strumento più efficace e innovativo per fare dell’Italia intera una potenza industriale. L’allontanamento da questi esiti, nella fase successiva dominata dalla crisi petrolifera e dalle politiche di ristrutturazione industriale, pur determinando una netta inversione di tendenza, non ha messo in discussione il valore dell’esperienza iniziale della Cassa per il Mezzogiorno, capace di aprire la strada alla crescita economica italiana negli anni del boom.Historiography focusing on the Cassa per il Mezzogiorno is indeed vast and developed not only in regard to the main issues concerning the extraordinary intervention, but also to the various sectorial and territorial articulations public interventions for the recovery of Southern Italy undertook. Achieving a punctual reconstruction of the goings-on of the Cassa, an istitution that, for more than forty years –despite some differences in planning during its various phases– operated as an instrument to implement the strategies focusing on developing Southern Italy, requires a very deep commitment. However, an effective overall view can be reconstructed by interpreting a public intervention model strictly linked to the concrete economic events and to the trends of those industrial processes implemented in Southern Italy, even without going through a detailed chronicle of this entity.The choice of a long

  12. Iga neljas Eestimaa laps elab allpool vaesuspiiri / Elle Kull

    Index Scriptorium Estoniae

    Kull, Elle, 1952-

    2007-01-01

    Ilmunud ka: Lääne Elu, 25. jaan. 2007, lk. 2; Valgamaalane, 25. jaan. 2007, lk. 2; Lõunaleht, 25. jaan. 2007, lk. 2; Sakala, 26. jaan. 2007, lk. 2; Den za Dnjom, 26. jaan. 2007, lk. 18; Meie Maa, 26. jaan. 2007, lk. 2; Nädaline, 30. jaan. 2007, lk. 4; Vooremaa, 30. jaan. 2007, lk. 2; Järva Teataja, 1. veebr. 2007, lk. 2. Yorki ülikooli ja UNICEF-i laste heaoluindeksi uuring paigutab Eesti lapsed EL-i 25 riigi seas eelviimasele kohale. Parlamendiliige tõstatab Eesti perepoliitika valupunktid

  13. On piecewise affine interval maps with countably many laps

    Czech Academy of Sciences Publication Activity Database

    Bobok, J.; Soukenka, Martin

    2011-01-01

    Roč. 31, č. 3 (2011), s. 753-762 ISSN 1078-0947 Institutional research plan: CEZ:AV0Z20760514 Keywords : dynamical systems * entropy Subject RIV: BA - General Mathematics Impact factor: 0.913, year: 2011 http://www.aimsciences.org/journals/displayArticlesnew.jsp?paperID=6407

  14. Kas pangalaen või kolmas laps? / Tiina Oraste

    Index Scriptorium Estoniae

    Oraste, Tiina

    2007-01-01

    Ilmunud ka:: Järva Teataja, 1. nov. 2007, lk. 2; Sakala, 1. nov. 2007, lk. 2; Valgamaalane, 1. nov. 2007, lk. 2; Lääne Elu, 1. nov. 2007, lk. 2; Vooremaa, 1. nov. 2007, lk. 2; Hiiu Leht, 2. nov. 2007, lk. 2; Harju Ekspress, 2. nov. 2007, lk. 6; Kuulutaja, 2. nov. 2007, lk. 4; Koit, 3. nov. 2007, lk. 6; Oma Saar, 6. nov. 2007, lk. 5; Sõnumitooja, 7. nov. 2007, lk. 2; Vali Uudised, 7. nov. 2007, lk. 2; Türi Rahvaleht, 16. nov. 2007, lk. 4. Autor selgitab majandus- ja kommunikatsiooniminister Juhan Partsi ettepanekut, et riik peaks aitama eluasemelaenu tagasimaksmisel mitmelapselisi perekondi

  15. 20th Century Fashions. Teacher Edition. Marketing Education LAPs.

    Science.gov (United States)

    Hawley, Jana

    This learning activity packet is designed to help students to acquire a competency: how to use an understanding of fashion history in preparation for a career in the fashion industry. The unit consists of the competency, three objectives, suggested learning activity, transparency masters, and a pretest/posttest with answer keys. The activity is a…

  16. Careers in Fashion. Teacher Edition. Marketing Education LAPs.

    Science.gov (United States)

    Hawley, Jana

    This learning activity packet is designed to help students to acquire a competency, namely: how to use knowledge of careers in the fashion industry to gain information about their career choices. The unit consists of the competency, three objectives, suggested learning activities, transparency masters, handout materials for activities, and a…

  17. Role of heat equation in lap joint for welding process

    Science.gov (United States)

    Kumar, P.; Rohit, Sooraj

    2017-07-01

    Welding is predominantly used in industrial purposes and growth in their industry, which gives exact welding and more efficient. The major advantage of using this welding technique at initial stage it takes very low heat to weld the portion and gives a good result of low distortion in modules. In this context, two dissimilar metals copper and nickel are chosen for analysis in tungsten inert gas welding (TIG) in which length is 300 mm and breadth is 100 mm thickness 15 mm welded at room temperature a welded portion zone is formed simulation analysis has done on CATIA® and ANSYS®and MATLAB® code is generated for calculating temperatures at each node to calculate temperature at each node a new technique is used tri-diagonal matrix algorithm is used (TDMA) Steady state one dimension heat is calculated results compared between simulation analysis and analytical analysis temperature at each node is calculated both the temperatures are equal with error.

  18. CLINICAL STUDY ON LAP A ROSCOPIC MANAGEMENT OF VARICOCELE

    Directory of Open Access Journals (Sweden)

    Prabhakara Rao

    2015-10-01

    Full Text Available AIM OF THE STUDY: To determine the effectiveness of laparoscopic varicocelectomy in the management of infertility and pain. MATERIALS AND METHODS: Varicocele is a major identifiable cause of male infertility. It is often associated with pain , abnormal testicular histology and seminal parameters. This prospective study was conducted on 22 patients over a period of 2 years from October 2012 - 14 for whom laparoscopic varicocelectomy was done. RESULTS: Pain decreased in 71% of cases but not improved in 29% of cases. There was no significant improvement in semen volume but there was significant increase in sperm density and motility. CONCLUSION: Laparoscopic varicocelectomy is a minimally invasive procedure with shorter convalescence less operative morbidity and early return to no rmal activity. It is effective in the management of pain associated with varicocele and it significantly improves semen quality

  19. Keystone ø-lap til rekonstruktion af huddefekter

    DEFF Research Database (Denmark)

    Breiting, Line Bro; Venzo, Alessandro; Dahlstrøm, Karin

    2009-01-01

    losses. Furthermore, it is technically easy to perform and thus may be performed by trainee surgeons as well as senior surgeons. The cosmetic result is excellent and far superior to the alternative skin grafting with its color differences and contour defect. In addition, many patients may be treated...

  20. Passita staarid : laps- ja teinipopi tippe / Berk Vaher

    Index Scriptorium Estoniae

    Vaher, Berk, 1975-

    2008-01-01

    Berk Vaher leiab youtube'ist ja heliplaatidelt alaealiste esitatud laule: The Third Wave "Eleanor Rigby" (1969/1970), Defranco Family feat Tony Defranco "Heartbeat (It's A Love Beat)" (1973), Langley Shools Music Project "Space Oddity" (1976), Elektrooniku seiklused "Krõlatõje katsheli" (1979), The Kelly Family "David's Song (Who'll Come With Me)" (1979/1989), Nikka Costa "(Out Here) On My Own" (1981), Kris Kross "Jump" (1992), Eesti Raadio Laululapsed "Öös on silmi" (2001), Plixid "Questions" (2007), Miip "Ära ole kuri!" (2008)

  1. Millal laps tööle panna? / Kristiina Illak

    Index Scriptorium Estoniae

    Illak, Kristiina

    2007-01-01

    Mõni hakkab raha teenima õige varakult, teine ajab tööl käimata ülikooli lõpuni läbi. Kumb tee on õigem? Lapse töötamise ja kooli kõrvalt töötamise üle arutlevad Katrin Peitre, Toomas Kibus, Lynn Veski ja Tiina Laanem

  2. Summary of Synthetic Lap Polishing Experiments at LLNL, FY95

    International Nuclear Information System (INIS)

    Nichols, M A

    2001-01-01

    The purpose of this research was to support the optics finishing development work for the NIF, the National Ignition Facility. One of the major expenses for the construction of NIF is the cost of finishing of the large aperture optics. One way to significantly reduce the cost of the project is to develop processes to reduce the amount of time necessary to polish the more than 3,000 amplifier slabs. These slabs are rectangular with an aspect ratio of more than twenty to one and are made of a very temperature sensitive glass, Nd doped phosphate laser glass. As a result of this effort, we could potentially reduce the time necessary to polish each surface of an amplifier from 20-30 hours of run time to under an hour to achieve the same removal and still maintain a flatness of between one to three waves concave figure. We also feel confident that we can polish rectangular thermally sensitive glass flat by use of temperature control of the polishing platen, pad curvature, slurry concentration with temperature control, pad rotation, and pressure; although further, larger scale experiments are necessary to gain sufficient confidence that such a procedure could be successfully fielded

  3. Laps ja lapsekesksus / Ugaste [Saar] Aino, Tiia Õun

    Index Scriptorium Estoniae

    Ugaste, Aino

    2001-01-01

    26.-27. okt. 2001 toimus Jyväskyla Ülikoolis FACEI (The Finland Association for Childhood Education International) rahvusvaheline kasvatusalane konverents, mille temaatika oli seotud õpikeskkonnaga. Kokkuvõtted Stockholmi Ülikooli professori Gunila Dahlbergi ja Oulu Ülikooli professori Eeva Hujala ettekannetest

  4. Construct validity of the LapSim: can the LapSim virtual reality simulator distinguish between novices and experts?

    NARCIS (Netherlands)

    van Dongen, K. W.; Tournoij, E.; van der Zee, D. C.; Schijven, M. P.; Broeders, I. A. M. J.

    2007-01-01

    BACKGROUND: Virtual reality simulators may be invaluable in training and assessing future endoscopic surgeons. The purpose of this study was to investigate if the results of a training session reflect the actual skill of the trainee who is being assessed and thereby establish construct validity for

  5. “Storm Landscape”: from the reality effect to the moralized mimesis. The examples of Apollonius Rhodius and Quintus of Smyrna. "Le paysage de tempête" : de l'effet de réel à la mimesis moralisée. Les exemples d'Apollonios de Rhodes et de Quintus de Smyrne 'Il paesaggio della tempesta': dall'effetto realistico alla mimesi moralizzante. Gli esempi di Apollonio Rodio e Quinto Smirneo

    Directory of Open Access Journals (Sweden)

    Laury-Nuria André

    2013-05-01

    omerico. La tempesta è concepita come una punizione divina, una nemesis che punisce la hubris dei conquistatori: la descrizione impiega un vocabolario assiologico che non tarda a fare di questo paesaggio epico un’apertura alla riflessione filosofica. La mimesis non è più sinonimo di effetto realistico ma si approssima a una dimensione etica nel momento in cui si allontana dalla riscrittura omerica.Come comprendere il fatto che la potenza evocativa dell’effetto realistico assicurata dalla mimesis (nel senso di imitatio, costitutiva del paesaggio epico, non passi più per un “paesaggio in movimento” che presenta in modo patetico la violenza e la morte, ma per un pathos che non è più percepibile che attraverso l’uso di un vocabolario assiologico e filosofico? Questa comunicazione intende perciò mostrare come il concetto di mimesis evolva da un senso d’imitazione e di effetto realistico a una comprensione più etica e moralizzata alla fine dell’antichità. Il paesaggio costituisce dunque uno dei luoghi di ossservazione privilegiati per la messa in opera di una mimesis evolutiva in età ellenistica e imperiale.The ancient lanscape as represented in the hellenistic epic and later is a privileged field of investigation to examine the role and evolution of the ancient concept of mimesis. An epic landscape in particular, that of the sea storm, will hold our attention: the transition at the Symplegades in Apollonius Rhodius (Argonautica II, 549-610 and the final storm which closes the Posthomerica of Quintus Smyrnaeus offer one of the most significant comparative studies. Indeed, the landscape of the Symplegades, landscape of extremes, is a place where all elements are reversed, and the poet portrays a scene of chaos, near the unrepresentable. Yet to reread the passage, we can see that it is anything but chaotic: very constructed through regular narrative rhythm organized in three phases that mimic the movements of the waves, it creates a real

  6. Educazione alla legalità, alla responsabilità sociale e all’inclusione. Una ricerca sui temi dell’antimafia sociale

    Directory of Open Access Journals (Sweden)

    Laura Corazza

    2016-11-01

    Full Text Available This research is part of an agreement with the regional government. The study focused on education for democratic lawfulness and civic responsibility by observing educational courses run by Libera on property confiscated from organized crime. The first outcome consisted of setting out pedagogical paradigms for education on democratic lawfulness and anti-mafia education. In order to do this, volunteers from schools were observed over a number of weeks while they lived in properties confiscated from mafia and worked on the land, which had been entrusted to co-operatives as part of an anti-mafia social training Program. Three Italian regions were involved: Piemonte, Emilia Romagna and Puglia. The second outcome was the production of multimedia materials for teaching, and specific courses, which were held in local secondary schools.

  7. Un incontro con Mattia Crespi docente di Geomatica alla Sapienza di Roma

    Directory of Open Access Journals (Sweden)

    Renzo Carlucci

    2015-03-01

    Full Text Available A meeting with Mattia Crespi Mattia Crespi, full professor of Geomatics at La Sapienza University in Rome, to talk about the evolution of Geomatics, the new line of research in the field of 3D sensors and the content of the Italian Spatial Data Infrastructure.

  8. Viking Line toob Rosella uuest aastast Eesti lipu alla / Signe Kalberg

    Index Scriptorium Estoniae

    Kalberg, Signe, 1959-

    2005-01-01

    Viking Line'i parvlaev Rosella hakkab kulude kokkuhoiu, äritegevuse tasuvuse ja konkurentsivõime taastamise huvidest sõitma uuest aastast Eesti lipu all ning vahetab välja senise laevameeskonna. Viking Line'i infojuhi Johanna Boijer-Svahnströmi kommentaare

  9. Uudiste lõpp ehk kuidas Facebook ajakirjanduse alla neelas / Priit Hõbemägi

    Index Scriptorium Estoniae

    Hõbemägi, Priit, 1957-

    2016-01-01

    Priit Hõbemägi refereeris Cambridge ülikooli professori ja Columbia ajakirjanduskooli digitaalse ajakirjanduse keskuse direktori Emily Belli meedia­maailmas laineid löönud kõnet sotsiaalmeedia ettevõtete mõju kasvust uudiste levitamise ja sellega raha teenimise üle

  10. Considerazioni sulla receptio legis alla luce del m.p. Mitis Iudex Dominus Iesus

    Directory of Open Access Journals (Sweden)

    Maria Chiara Ruscazio

    2018-03-01

    ABSTRACT: Reception of law can be described as the process by which the recipients of a canonical law verify its reasonableness. This process appears mostly in the material observance of the law. The essay examines firstly the theological and ecclesiological legitimacy of reception, and then it explores which are its effects upon the binding force of the law and when they occur. Finally, it tries to employ this concept in describing the way in which the m.p. Mitis Iudex has been accepted and implemented in some local Churches.

  11. La disciplina dello SME ha contribuito alla convergenza dell'inflazione?

    Directory of Open Access Journals (Sweden)

    L. BINI SMAGHI

    1994-06-01

    Full Text Available The paper focuses on the cross-section comparison of inflation performance inside and outside the EMS. The evidence contained in the literature is first reviews. The author then examines some of the limitations of the analysis contained in the literature and presents new empirical evidence that takes into account some aspects that were previously ignored.

  12. La leadership politica in Italia alla luce della tradizione comica nazionale

    OpenAIRE

    Maria Pia Pozzato

    2014-01-01

    Political leadership in Italy in the light of the national comical traditionThis essay deals with humour and satire in politics. The issue of humour is contextualized within a wider cultural phenomenon called ‘show civilisation’ or ‘schermopolis’, i.e. the pervasiveness of screens in our everyday life. In doing so I will consider the role of new media and social networks in fostering the use of humour in political discourse. Next I will try to find a new framework for forms of popularity in p...

  13. Dalla creazione alla programmazione. Il concetto di vita nell’era della biologia sintetica

    Directory of Open Access Journals (Sweden)

    Luca Lo Sapio

    2014-06-01

    Full Text Available This paper aims to organize a reflection about the recent developing field of synthetic biology. It is structured into three main parts. The first one tries to point out the features of this emerging field (the analogies and the differences with the genetic engineering; the second one analyzes the terms and the concepts we can find in the fundamental article by Venter et al. (and in the recent article published by La Jolla Institute’s researchers; the third one delineates the principal outcomes of synthetic biology’s applications, in particular, for the formulation of the concept of life. Therefore it is proposed a connection between artificial life’s science and human enhancement. In fact I think it is possible to clarify human enhancement problem by a specific investigation of synthetic biology’s main characteristics.

  14. “La Svizzera. Una prigione?” Reazioni letterarie e pittoriche alla ristrettezza elvetica

    Directory of Open Access Journals (Sweden)

    Maurizio Basili

    2011-05-01

    Full Text Available The border is not just a line; it's a space which shows a sense of belonging to a community and to a region. Swiss borders appear extremely strict and insurmountable if we consider the essay by Friedrich Dürrenmatt Die Schweiz: ein Gefängnis (1990 in which he compares the small country to a prison: the Swiss themselves choose this detection because only in this prison they feel safe from outward aggression. Neutrality is a source of suffering and has an ambivalent connotation: it makes sure to be free from the worldwide conflicts but, at the same time, it makes prisoners because it limits the freedom to act. What emerges from the words of one of the most important Swiss writers of the twentieth century and from the most part of the Swiss intelligentsia is the indication of a deep identity crisis, a desire to escape the narrowness Paul Nizon wrote about in 1973 in his essay Diskurs in der Enge, in which he also implies a lack of freedom in Swiss Literature: in Swiss daily life nothing happens. The Swiss writer could describe his daily life, but he would be obvious, meaningless or simply boring. Narrowness is therefore the main precondition for a Swiss artist and it causes the escape. Escape and isolation are recurring themes in the art of painting (for example in the works of Giacometti and Meret Oppenheim too.

  15. Il grido di Abacuc. La questione ecologica alla luce delle istanze del giusnaturalismo cristiano contemporaneo

    Directory of Open Access Journals (Sweden)

    Cristiana Maria Pettinato

    2014-10-01

    Full Text Available Contributo sottoposto a valutazioneSOMMARIO: 1. Ecologia e religioni. Il rapporto uomo-natura nella visione escatologica dell’unità tra creazione e storia. Critiche all’antropocentrismo cristiano e derive panteistiche - 2. Chiesa cattolica e questione ecologica. Il nuovo imperativo categorico: l’ecologia umana nel Magistero pontificio post-conciliare - 3. L’ecologia umana come preoccupazione comune alle principali Chiese cristiane- 4. Riflessioni sulla causa del disastro ecologico umano-ambientale: la soluzione del problema nella natura giuridica della persona umana. Abstract In the present work – based on a suggestion coming from the Scriptures- we investigated the relashionship between human disobedience to the commands of God and the revolt of the creation that manifests in the natural upheavals.Become one of the most challenging cultural issues for the modern world, even the religious faiths reflect on the ecological question, because it regards the deep relashionship between man and all over the world created.But the ebraic-christian monotheism develops an ontological doctrine of creation purposeful orientated toward redemption.The christian revolution is that man is the centre of the universe and ontological different from the others creatures, in respect of which is vested of responsability. But humanity power has become limitless, consequently new methaphisic and religious tendences offer a vision of nature deified (Deep ecology-Gaia, in which man depersonalized is privated of moral and legal responsibility.In post-conciliar magisterium Catholic Church addresses the ecological problem interpreting it as an anthropological question.It’s useless taking care of the environment without priority to the human rights. This is one of the most important principle of Social Doctrine of Catholic Church. The ecological disaster is an human fault, and the solution of this emergency is a revaluation of natural law, a duty for the common man and the jurist.

  16. Notarikandidaadiks sai alla viiendiku soovijatest : Notarite Koja viimase aja üritused / Eve Strang

    Index Scriptorium Estoniae

    Strang, Eve

    1999-01-01

    20. veebruaril 1999. a. Tallinnas toimunud pärimisseaduse alasest seminarist, 8.-9. märtsil 1999. a. Tallinnas toimunud notarikandidaatide konkursist, 13. märtsil 1999. a. Pärnus toimunud Notarite Koja aastakoosolekust ning 25.-26. märtsil 1999. a. Šveitsis toimunud Notarite Kodade ühisseminarist

  17. Domingo de Ramos, dalla violenza urbana alla solidarietà marginale

    Directory of Open Access Journals (Sweden)

    Riccardo Badini

    2016-12-01

    Full Text Available The article aims to analyze the poetry of Domingo de Ramos (Peru 1960 through themes like violence, urban decay and migration and presents the translation of an unpublished poem. A path is traced from the vanguards to the socio historical and political context of the  80s Peru, not to mention the innate inclination of the poet for marginal realities.

  18. Bioetica dal comandamento. Intorno alla riflessione ebraica sulla fecondazione assistita e l’eutanasia

    Directory of Open Access Journals (Sweden)

    CAPORALE, MARIANGELA

    2017-06-01

    Full Text Available Bioethics from Commandment. Concerning Jewish Reflection on FIVET and Euthanasia This paper focuses on the specific nature of the Jewish bioethical thought. My interest regards the peculiarity of the biblical Jewish approach to biomedical questions like FIVET and euthanasia. The paper points out the relationship between Jewish and Christian bioethical view about these questions and it shows the analogies and the differences typical of two creationist faiths.

  19. Il fascino oscuro dell’inflazione alla scoperta della storia dell’universo

    CERN Document Server

    Fré, Pietro

    2009-01-01

    È dalla più remota antichità che l’uomo si interroga sulla struttura dell’Universo e sulle leggi che lo governano. Ma il progresso compiuto all’inizio del XX secolo non ha paragoni rispetto a quello di tutti i secoli precedenti: nel 1915 fu formulata la relatività generale, indispensabile per inquadrare tutti i fenomeni cosmici e astrofisici; tra il 1920 e il 1930 furono determinate le reali dimensioni dell’Universo visibile e fu scoperta la sua costante espansione. La cosmologia ha poi fatto un grande salto di qualità a cavallo tra la fine del XX secolo e l’inizio del XXI, quando una serie di osservazioni ha confermato che: L’Universo è spazialmente "piatto", in seguito all’inflazione cosmica che, una frazione di secondo dopo il Big Bang, ne ha gonfiato le dimensioni di decine o centinaia di miliardi di volte. L’Universo è costituito al 70% da energia oscura e al 24% da materia oscura: la materia visibile, cioè stelle e galassie, rappresenta solo il 6% del totale. Attualmente l’espa...

  20. Dalla trasmissione interculturale alla transculturalità dei Diritti Umani nella filosofia arabo-islamica contemporanea

    Directory of Open Access Journals (Sweden)

    Sarhan Dhouib

    2011-01-01

    Full Text Available From Intercultural Mediation to the Transculturality of Human Rights in Contemporary Arab-islamic Philosophy - This article explores the point of view of Arab-Islamic philosophy with respect to the problem of human rights: their transcultural value and their intercultural transmission. The main focus of the argument is on the problems that hinder the universal validity of human rights from being established. The investigation explores primarily the following questions: How is it possible to achieve an intercultural extension of the basic laws on which human rights are grounded? How is it possible to ensure that human rights are universally acknowledged and respected? Is there a contradiction between cultural pluralism and the universal acknowledgment of human rights? What arguments might support the idea of the universal value of human rights?

  1. Implicazioni pratiche legate alla ritenzione di solvente nei p.v. reticolabili a Tamb

    Czech Academy of Sciences Publication Activity Database

    Lewin, L. A.; Douglas, C. B.; Dušek, Karel; Dušková, Miroslava; Vlasák, P.

    2005-01-01

    Roč. 81, č. 1 (2005), s. 21-29 Institutional research plan: CEZ:AV0Z40500505 Keywords : polymer coatings * solvent evaporation * polyurethane film formation Subject RIV: CD - Macromolecular Chemistry http://www.gbp.it/copiasitopv_inlinea/1_paginapv.html

  2. Incentivi reputazionali alla cooperazione in un gioco competitivo tra adolescenti : Uno studio sperimentale

    NARCIS (Netherlands)

    Giardini, Francesca; Guazzini, Andrea; Duradoni, Mirko; Paolucci, Mario; Brigida, Lucia; Vilone, Daniele; Bagnoli, Franco

    2016-01-01

    Reputation is one of the most effective solutions to the so-called «puzzle of cooperation», but it is usually studied in contexts in which information is not ambiguous and there are no incentives towards strategically using it. In this study, we test wheter the possibility of being evaluated (with a

  3. Ipotesi di variazioni del clima correlate alla precessione dei nodi lunari

    Science.gov (United States)

    de Donà, Giuseppe

    2005-04-01

    The paper shows the existence of a striking correlation between seasonal and yearly mean temperatures, recorded from 1925 through 2003 at the Arabba Avalanche Center, and the Moon's latitude over the ecliptic during the same period. Also the mean amount of rain in the same time period may be controlled by the Moon, but this quantity shows an anti-correlation to the lunar latitude instead of the direct correlation displayed by the mean temperatures.

  4. Här är alla lika! Jämlikhetsideologi och konstruktion av den

    Directory of Open Access Journals (Sweden)

    Tommaso M. Milani

    2009-01-01

    Full Text Available Here we’re all equal! The ideology of equality and the constructionof ‘Otherness’ in media and educational settings. The focus ofthis article lies on the question of how linguistic diversity is talked about and dealt with in contemporary Sweden. More specifically, we examine media utterances which target the linguistic practices of young men who are perceived as “non-Swedish”. We also investigate the ways in which these young men who are the object of media attention actually use language in the classroom. The key argument of the article is that media utterances and classroom interactions have a common denominator: they are underpinned by a shared discursive constraint – a well-established ideology of equality, according to which individuals should be treated as equal irrespective of their social, ethnic and linguistic backgrounds. Our aim is to show the ways in which this ideology is normative insofar as it defines the discursive conditions for the creation of boundaries between “Us” and “Them”.

  5. Razionalismo, politica e teoria della conoscenza. Un contributo alla filosofia arabo-islamica del presente

    Directory of Open Access Journals (Sweden)

    Mohammed Abed Al-Jabri

    2011-01-01

    Full Text Available Rationalism, Politics, and Theory of Knowledge. A Contribution to Contemporary Arab-Islamic Philosophy - The present text is a significant excerpt from the interview released in 1981 by the Moroccan philosopher Mohamed Abed Al-Jabri in the journal al-thaquafa- al-djadida [The New Culture]. The text was later revisited by Al-Jabri himself and published in 1991 with the title li'anna al-aqlaniya darura [Why rationalism is necessary] in a book on the relationship between tradition and modernity in the Arab-Islamic culture, At-turat wa-I-hadatha [Tradition and Modernity]. The interview deals with some of the central points in the contemporary debate on the social, political and cultural renewal of the Arabic world. Al-Jabri thinks that a critical perspective on Arab-Islamic culture must be developed. He maintains that in the Arab-Islamic world there is an enormous need for philosophy – discussion and rational argumentation – and for rationalism. Rationalism would contribute, among other things, to freeing politics and science from the chains of dogmatism, religion and tradition.

  6. Alla ska ha kul! : Parodisk barnkultur och publik i nutida kommersiell animation

    OpenAIRE

    Milia, Mirella

    2006-01-01

    Barnfilmen har länge haft en undanskymd plats inom filmteori. Man har tidigare intresserad sig för den i termer av ideologisk påverkan eller pedagogisk nytta alternativt onytta, men intresse för frågor som rör mer specifika textmekanismer har hittills dröjt. En sådan fråga är, exempelvis, hur barnfilmen konstruerar eller implicerar sin egen åskådare. Med tanke på att motsvarande problema¬tik har dragit till sig många barnlitteraturforskares intresse, är det märkligt att en liknande omsorg int...

  7. Archivi e biblioteche alla fine del Granducato di Toscana in uno scritto di Galeotti

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    Carlo Vivoli

    2016-12-01

    Full Text Available In 1855 Leopoldo Galeotti publishes an important essay on the recently established Central State Archive of Florence in Archivio Storico Italiano. The lawyer from Pescia, also thanks to the advice provided by the director of the Archive, Francesco Bonaini and his collaborators, constructs an effective summary of the works to be done to gather together and organise the Florentine public archives, and provides important suggestions to connect not only the archives but also the libraries of the Tuscan capital to the new threads emerging in historical research.

  8. Eesti koondas Aasia uurijad ühise mütsi alla / Karin Dean

    Index Scriptorium Estoniae

    Dean, Karin

    2014-01-01

    Tallinna Ülikool, Tartu Ülikool ja Tallinna Tehnikaülikool lõid Aasia Uuringute Kompetentsikeskuse (AUKK), et koondada Aasia tänapäevase majanduse, poliitika ja ühiskondade teemal teadustööd tegevad teadlased Eesti ülikoolides ühte võrgustikku et pakkuda info- ja ideevahetust ülikoolide, avaliku sektori ja ettevõtjate vahel

  9. Dalla neuroeconomia alla neuroetica: verso una neuroscienza delle decisioni individuali e socio-morali

    Directory of Open Access Journals (Sweden)

    Maria Arioli

    2017-08-01

    Full Text Available Neuroeconomics and neuroethics are subfields of cognitive neuroscience that address the neural correlates of distinct, although strongly intertwined, facets of decision-making. While neuroeconomics investigates the neural mechanisms underlying the maximization of personal economic utility, neuroethics integrates such knowledge with that provided by social neurosciences, in order to address typical questions in ethics and moral philosophy. We review the available research to contrast the hypothesis that both individual economic and socio-moral choices rely on a common brain network receiving domain-specific inputs (Extended Common Currency Schema and the claim that a specific brain network underpins choices in a socio-moral context (Social-Valutation-Specific Schema. In line with the former model, currently available evidence supports the existence of a single brain network associated with both choice types, regardless of the economic individual vs. socio-moral decisional context.

  10. Pangad võtavad laenusoovijad põhjalikult luubi alla / Kaire Uusen

    Index Scriptorium Estoniae

    Uusen, Kaire

    2008-01-01

    Pankades rakendatavast uue süsteemist Basel 2, mis on kohustuslik kõigile Euroopa Liidu pankadele. Pangatöötajate arvamusi laenuandmise tingimuste kohta. Kommenteerib Priit Kiilmaa. Vt. samas: Pangad hoiatavad SMS-laenu eest

  11. 'Prima furon le cose e poi i nomi'. Riflessioni attorno alla filosofia del linguaggio di Galileo

    NARCIS (Netherlands)

    Palmerino, C.R.

    2016-01-01

    This article addresses an aspect of Galileo’s thought that has hitherto attracted little attention, that is to say, his philosophy of language. First of all, we try to show that Galileo’s reflections on the ambiguous and conventional nature of verbal language, though not expounded systematically,

  12. H. Sapiens digitale: dagli immigrati digitali e nativi digitali alla saggezza digitale

    Directory of Open Access Journals (Sweden)

    Marc Prensky

    2010-01-01

    Full Text Available This is the translation of a paper by Marc Prensky, the originator of the famous metaphor digital natives - digital immigrants. Here, ten years after the birth of that successful metaphor, Prensky outlines that, while the distinction between digital natives and immigrants will progressively become less important, new concepts will be needed to represent the continuous evolution of the relationship between man and digital technologies. In this paper Prensky introduces the concept of digital wisdom, a human quality which develops as a result of the empowerment that the natural human skills can receive through a creative and clever use of digital technologies.

  13. Saksa teadlane hoiatab: "Tallinn jääb vee alla!" / Dieter Meissner ; intervjueerinud Maris Sander

    Index Scriptorium Estoniae

    Meissner, Dieter, 1954-

    2011-01-01

    Intervjuu Eestis päikesepaneelide tehnoloogiat arendava professoriga. Teadlase hinnangul pole tuumaenergia Eestis võimalus, kaugemas perspektiivis on Eestil energia tootmiseks kaks võimalust: kasutada põlevkivi või minna üle päikese- ja tuuleenergiale. Päikeseenergia kasutamisest Saksamaal

  14. Sõjatandri puudumine ajab Eesti sõdurid Riia alla / Peeter Kuimet

    Index Scriptorium Estoniae

    Kuimet, Peeter

    2006-01-01

    Õppusteks vajaliku suure polügooni puudumise tõttu pidi elukutselistest sõduritest koosnev Scoutspataljon korraldama õppuse Gungnir 2006 Lätis asuval Adazhi polügoonil, kus on võimalik kasutada ka reaalset lahingumoona. Kaart: Adazhi polügoon. Lisa: Scoutspataljon

  15. Religioni e ateismi: una complexio oppositorum alla base del neo-separatismo europeo

    Directory of Open Access Journals (Sweden)

    Nicola Colaianni

    2011-06-01

    The European Union is not interested in religious phenomenon. It’s a form of separatism between State and Church. Yet the last Treaty about the Union functioning stated an “open, transparent and regular dialogue” between the Union and the Churches and the philosophical or non-confessional organizations alike. So religions and atheisms, the exact opposites, are not only recognized but also linked as complexio oppositorum. That originates a pluralistic separatism. By means of constitutional law research this paper demonstrates that this new-separatism is new for the Europe but usual for the U.S. and therefore it contributes a long way towards a rapprochement between Europe and America from the constitutional point of wiew.

  16. Afganistan jääb USA sõduriteta terrori alla / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2011-01-01

    Afganistanis on sagenenud Talibani korraldatud enesetapurünnakud, surma on saanud president Hamid Karzai vend ja mitu mõjukat nõunikku. Autori sõnul on mitu võimalust, et Afganistanis puhkeb taas kodusõda

  17. Mundrimehe alla ajanud politseiniku varem joobnult tehtud avarii vaikiti maha / Oliver Rand

    Index Scriptorium Estoniae

    Rand, Oliver, 1971-

    2008-01-01

    Politsei vaneminspektor Kalle Kolk, kes sõitis Tartu abipolitseinikule otsa, tegi avarii ka 2003. aastal. Lõuna politseiprefekt Aivar Otsalt põhjendab Kalle Kolgile teenistusmärgi andmist 2007. aastal

  18. Krediidipank läks Vene kapitali kontrolli alla / Peeter Raidla

    Index Scriptorium Estoniae

    Raidla, Peeter, 1955-

    2005-01-01

    Ilmunud ka: Delovõje Vedomosti 10. aug. lk. 2. Vene kapitalile kuuluv Latvian Business Bank omandas aktsiaostude tulemusena enamuse Eesti Krediidipangast. Diagramm: Krediidipanga aktsionärid. Vt. samas lühiintervjuud Krediidipanga juhatuse esimehe Andrus Klugega

  19. Teorie corporativiste nella Grecia del primo dopoguerra (1922-1940: dalla teoria alla prassi

    Directory of Open Access Journals (Sweden)

    Spyridon Ploumidis

    2017-03-01

    Full Text Available In Greece, during the first postwar period, similarly to what happened in Italy and Germany, a new way of understanding the relationships among State, economy and society appeared: the so-called “authoritarian” corporatism. The fall of the political liberalism in the hellenic country came with a deep crisis in the certainties about solidity and utility of economic liberties which derived in the establishment of the Kondylis and Metaxas dictatorships, who are the supporters of the greek government control. This paper wants to analyze, through the normative innovations and the attempts of interventions in the hellenic productive system, how the public authorities have tried to aligned themselves with the control government manners which evolved and established in the rest of Europe.

  20. Siim Kallas seab Lumani argumendid kahtluse alla / Kadri Paas ; kommenteerinud Norman Aas, Juhan Põldroos

    Index Scriptorium Estoniae

    Paas, Kadri, 1982-

    2009-01-01

    Seaduseelnõust, mille eesmärgiks on tõhustada võitlust kartellidega ja muude raskete konkurentsiõiguse rikkumistega nn leebusprogrammi abil. Kommenteerivad peaprokurör Norman Aas ja Juhan Põldroos

  1. Agire affettivo, carisma e ascesi intramondana. Il contributo weberiano alla sociologia delle emozioni

    Directory of Open Access Journals (Sweden)

    Gregor Fitzi

    2012-03-01

    Full Text Available Max Weber has often been depicted as a rationalistic thinker, who did not acknowledge the role of emotions for social interaction. By contrast to that interpretation the paper shows what the theoretical significance of the analysis of emotions in Weber’s sociology is. Starting from the level of social action, emotional action is seen by Weber as the most important motive for the breakout of new frames of interaction in premodern societies. The development of Weber’s sociological theory of emotions can therefore be reconstructed following the architecture of his posthumous work “Economy and society”. There Weber exposes how the emotional motivation of action becomes on the one hand the leading impulse for the building of the horizontal social structure of Vergemeinschaftung and on the other for the vertical structures of the charismatic power. Latter is the most developed social structure based on emotional action. Its endurance is however limited in time. Everyday forms of social life must replace the charismatic ties if the social group wants to last over the period of emergency. Weber attention for this issue evidences his particular understanding of the sociological status of emotions that can be defined as a “liminal status”. Emotions can give impulsion to the developing of social relationships but in the long run they have to be replaced by other action forms as e. g. tradition or rationality. This assumption could lead to claim that especially in modern times the role played by emotions in the social domain is vanishing. Taking a look to Weber’s sociology of religion, this assumption may however be contradicted in a surprising way.

  2. Hindutva. La destra nazional-religiosa indù dalle origini alla conquista del potere

    Directory of Open Access Journals (Sweden)

    Luca Ozzano

    2007-07-01

    Full Text Available This paper deals with the evolution of the Hindu religious right and its role in Indian politics from the end of the 19th century to the present day. The first section takes into account early reform groups arisen at the time of the British colonial rule, and the process which led to the emergence of the ideology known as hindutva, with the creation of the Rāṣṭrīya Svayaṃsevak Saṅgh (RSS in the 1920s. The following part describes the growth of this organization and the creation of a network of RSS-affiliated groups (which is commonly referred to as Saṅgh Parivār, devoting particular attention to the most religiously-oriented of these organizations, the Viśva Hindū Pariṣad (VHP. The last section deals with the role played in Indian politics by the RSS-affiliated Bhāratīya Jantā Party (BJP – formed in 1980 – which led the political coalition ruling India from 1998 to 2004.

  3. Termodinamica aspetti recenti e applicazioni alla chimica e all'ingegneria

    CERN Document Server

    Carrà, Sergio

    1990-01-01

    Dalla fine del secolo scorso la termodinamica è stata applicata allo studio delle proprietà della materia e delle sue trasformazioni e si è andata via via evolvendo interessando campi diversi, come la meccanica statistica, la fisica molecolare, le scienze ambientali, la biofisica, la scienza dei materiali e le tecnologie chimiche....

  4. Codici alla mano. I due figli di Iorio in contenzioso estetico-giudiziario

    Directory of Open Access Journals (Sweden)

    Francesco de Cristofaro

    2012-10-01

    Full Text Available Il sottobosco ottocentesco delle transparodie – inversioni sessuali in chiave comica, con personaggi en travesti che riprendono per contrappunto figure mitiche dell’immaginario romanzesco e melodrammatico – risulta incomprensibile se si dimentica che già ad alcune figure carismatiche dell’individualismo moderno erano toccate in sorte evirazioni in piena regola (da The Female Quichotte in poi. A tale famiglia di testi si rifà anche un’opera pionieristica nella storia del diritto d’autore: Il figlio di Iorio (1904 di Eduardo Scarpetta, parodia de La figlia di Iorio di Gabriele D’Annunzio, dello stesso anno. La “commedia presepiana” – un po’ opera buffa stile belle epoque, un po’ parodia assai casareccia – provocò un piccolo terremoto giudiziario: una richiesta di consenso, una diffida, una querela per plagio, infine un processo fatto di portentose pezze d’appoggio, e con un’intera società cultural-mondana divisa in due – letterati vs commedianti, pianto vs riso, arte alta vs arte plebea, ecc. – , e alcuni intellettuali di prestigio coinvolti in qualità di periti. Caso interessantissimo di sociologia dell’arte, il processo D’Annunzio-Scarpetta è anche un cruciale episodio di storia della cultura: perché ciò che il tribunale ospitò fu anche un dilettantesco e appassionato brainstorming di “comparatistica forense”.

  5. Georg R. R. Martin: "Jää ja tule laul" filmi ei mahu / intervjueerinud Hendrik Alla

    Index Scriptorium Estoniae

    Martin, George R. R., 1948-

    2011-01-01

    USA telekanali HBO telesarjast "Troonide mäng", George R. R. Martini "Jää ja tule laulu" sarja esimese raamatu "Troonide mäng" teleekraniseeringust. Sarja esimene osa esilinastus USA-s 17. aprillil

  6. "Alla en Guatemala": Transnationalism, Language, and Identity of a Pentecostal Guatemalan-American Young Woman

    Science.gov (United States)

    Ek, Lucila D.

    2009-01-01

    This article examines the transnationalism of a Pentecostal Guatemalan-American young woman who is a second-generation immigrant. Amalia traveled to Guatemala from when she was six months old until her sophomore year in college. These visits to Guatemala have helped her maintain her Guatemalan language, culture, and identity in the larger Southern…

  7. Approccio pedagogico alla dimensione partecipativa per l’integrazione tra saperi materiali e immateriali

    Directory of Open Access Journals (Sweden)

    Giovanna Del Gobbo

    2011-11-01

    Full Text Available The present contribution is placed in the frame of international research project (Italy, Brazil, Cuba, Guatemala, Nicaragua that, from 2006 until 2010 with the involvement of ten Universities, developed the elaboration and the application of interdisciplinary theoretical and methodological models for the analysis and the valorization of human capital and territorial patrimony for the endogenous sustainable development. In the Project, the appeal to heuristic methodologies, for experiences’ analysis, has allowed to individualize interpretative categories that can represent criterions for transfer and dissemination of the research outputs. The dimension of “participation” appears surely an interesting category, especially if it is in relationship to the idea of development of the communities and the subjects. The contribution, further to a theoretical-methodological reflection on the “participation”, introduces the analysis of a research experience in the Mayan communities of Guatemala.

  8. Architettura e/è Geometria: dalla forma architettonica alla costruzione geometrica

    Directory of Open Access Journals (Sweden)

    Mariateresa Galizia

    2012-06-01

    Full Text Available L’avvento delle tecnologie digitali di acquisizione dati 3D ha proiettato gli studiosi dell’architettura in una dimensione del tutto inaspettata. Milioni di punti hanno travolto ricercatori e professionisti ancora culturalmente impreparati ad affrontare la rivoluzione digitale nel campo del Rilievo. Le nuvole di punti acquisite documentano e allo stesso tempo rappresentano la spazialità degli oggetti reali, tuttavia, nulla rivelano su forma e geometria, architettura e materia se non attraverso una successiva interpretazione. Il contributo vuole soffermarsi sulle implicazioni teoriche e applicative del processo di interpretazione dei dati acquisiti per la comprensione della geometria e sulla funzione euristica della modellazione digitale, nel passaggio dal “noto all’ignoto”, nella “ri-scoperta” della forma e quindi dell’idea progettuale.

  9. Commento di Modigliani alla teoria della disoccupazione di Sylos Labini (attraverso la corrispondenza del 1956

    Directory of Open Access Journals (Sweden)

    Antonella Rancan

    2014-09-01

    Full Text Available This note discusses Modigliani’s and Sylos Labini’s unemployment theory starting from a long letter Modigliani wrote to his friend and colleague, commenting the provisional edition of “Oligopolio e Progresso Tecnico” (1956. While in his influential article review (1958 Modigliani especially analysed and developed along original lines Sylos Labini’s microeconomic theory, in the letter he deeply discussed Sylos Labini macroeconomics. Modigliani criticized Sylos Labini’s classical definition of investment and the ensuing confusion between monetary and real causes of unemployment. From their correspondence their different theoretical perspective clearly stands out: Modigliani was interested in explaining the emergence of unemployment equilibrium in a static context, Sylos Labini its persistence as the result of structural changes.

  10. Includere fa la differenza? Il punto alla luce delle evidenze empiriche

    Directory of Open Access Journals (Sweden)

    Lucia Donata Nepi

    2013-09-01

    Full Text Available Il dibattito sull’educazione inclusiva ruota, tipicamente, intorno a due argomenti: i principi e le evidenze empiriche. Sul piano dei principi l’inclusione concerne il diritto di tutti gli studenti, compresi quanti sperimentano difficoltà di diversa natura, di avere accesso all’istruzione all’interno della scuola ordinaria. Ma una scuola che include è anche una scuola efficace? Che impatto ha l’inclusione sul rendimento degli studenti con bisogni speciali e dei loro compagni a sviluppo tipico? Qual è l’impatto sulla partecipazione sociale di tutti gli studenti? Ad oggi sappiamo che sul piano delle evidenze empiriche le risposte a queste domande sono molto lontane da risposte definitive. Lo scopo di questo lavoro è presentare lo stato dell’arte della ricerca internazionale sull’educazione inclusiva attraverso i risultati delle indagini più recenti.

  11. Grossatesta e la matematica dell'infinitoUna lettura del Commento alla Fisica

    Directory of Open Access Journals (Sweden)

    Massimiliano Luce

    2008-07-01

    Full Text Available Un fondamento teologico per la matematica dell'infinito: Dio come primo matematico in grado di numerare gli infiniti punti delle grandezze geometriche. A theological foundation for the mathematics of the infinity: God as the first mathematician, who is able to number the endless points of the geometrical size.

  12. Miks projektivõrgustikud projektmeeskondadele tuule alla teevad ? / Jonathan Cummings, Carol Pletscher

    Index Scriptorium Estoniae

    Cummings, Jonatahan

    2011-01-01

    Õige ja asjakohase oskusteabe leidmise keerukusest teadmistemahukate meeskonnaprojektide realiseerimisel. Projektvõrgustike analüüs. Skeemid: Mille poolest finaalijõudnud meeskonnad erinesid?, Kuidas projektvõrgustikud laiendavad meeskonna haaret?, Kuidas kasutada projektvõrgustikke?

  13. FEDERICO BORROMEO E I «RAGIONAMENTI» INTORNO ALLA «FESTA DELLE LINGUE»

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    Edoardo Buroni

    2017-03-01

    Full Text Available Figura di spicco della Milano secentesca, il cardinale Federico Borromeo resta legato nell’immaginario collettivo al personaggio del capolavoro manzoniano, mentre più limitati e più recenti sono gli studi che ne hanno analizzato direttamente l’ampia produzione scrittoria. Particolare interesse rivestono in questo senso i Sacri ragionamenti, le prediche tenute dall’arcivescovo e da lui stesso raccolte in lingua italiana, di cui qui si propone un breve studio relativamente alle omelie pentecostali. «Reasoning» regarding the «festival of languages» in 17th century Milan. Notes on the thought and language of Federico Borromeo A leading figure in 17th century Milan, Cardinal Federico Borromeo remains tied to the character in Manzoni's masterpiece in the collective imagination, while fewer, more recent studies have directly analyzed his written production. Of special interest in this regard are his Sacred writings, the sermons given by the Archbishop which he himself collected in Italian. We propose a brief study of the Pentecostal sermons.

  14. La memoria alla barocca ne L’isola del giorno prima di Umberto Eco

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    Agnieszka Piwowarska

    2012-12-01

    Full Text Available In his third novel The Island of the Day Before (L’isola del giorno prima Umberto Eco narrates a story of an unusual castaway named Roberto who – instead of being on a desert island – finishes up on an abandoned (but only at first sight ship. The article aims to analyze how the book’s main character, during his loneliness, reminisces about events from his past. And because the novel is set in the Baroque, Roberto´s memories respect the spirit of that time : numerous flashbacks are evoked by unexpected metaphors that link very distant things. The ship, which is for a young man a cumbersome prison, becomes a real Theatre of Memory, according to Giulio Camillo’s idea.

  15. La leadership politica in Italia alla luce della tradizione comica nazionale

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    Maria Pia Pozzato

    2014-12-01

    Full Text Available Political leadership in Italy in the light of the national comical traditionThis essay deals with humour and satire in politics. The issue of humour is contextualized within a wider cultural phenomenon called ‘show civilisation’ or ‘schermopolis’, i.e. the pervasiveness of screens in our everyday life. In doing so I will consider the role of new media and social networks in fostering the use of humour in political discourse. Next I will try to find a new framework for forms of popularity in politics by adapting to the current conjuncture the definitions given by Eric Landowsky at the end of the 1980s. Nowadays the politician-vedette is indeed the most popular form within the show civilisation phenomenon mentioned above. I will demonstrate that some Italian versions of this figure seem inspired by a rich Italian Comedy tradition. Finally, I will propose a number of hypotheses about the ways in which leaders obtain electoral consensus, for example through physical attractiveness, sympathy, and their ability to amuse people. In this perspective, a leader who is good for a laugh seems automatically a good leader.

  16. Dalla pizza alla cura dell’uomo, le abilità di RoDyMan

    Directory of Open Access Journals (Sweden)

    Nunzia Bonifati

    2014-12-01

    Full Text Available RoDyMan, acronym for Robotic Dynamic Manipulation, is a research project funded by the European Research Council to the CREATE Consortium and carried out at PRISMA Lab in the Department of Electrical Engineering and Information Technology of the University of Naples Federico II. The goal is the development of a service robot able to manipulate elastic and soft objects, which change continuously density and shape. These robots will be used not only in manufacturing but also as an aid to elderly or disabled people, for medical and surgical use, and in other manual activities. Preparing a pizza involves an extraordinary level of manual dexterity: for this reason a pizzaiolo robot has been conceived. It is also a tribute to Naples, at the forefront of technology, robotics and automation, but especially of culture and gastronomy, of which pizza is a symbol and tradition. Creating a robot able to manipulate objects like humans is one of the most sought and difficult challenges of robotics. It means to replicate skills that are the result of human biological and cultural evolution. This goal is arduous, mainly for two issues. First, we do not have a total knowledge of human nature, but this is the condition to be able to replicate the human functions in a machine. Second, there are many technical limits to implement a bio-inspired robot, not the least those making it user-friendly and aesthetically appreciated.

  17. Rossiiskim gruzam - rossiiskije konteinerõ = Russian containers for Russian cargoes / Alla Petrova

    Index Scriptorium Estoniae

    Petrova, Alla

    2004-01-01

    Autor teeb ülevaate transpordisüsteemi arengust, konteinerite tootmisest ja konteinervedude korraldusest NSV Liidus alates 1970ndatest ning analüüsib põhjuseid, miks käesoleval ajal tegelevad Venemaal konteinervedudega valdavalt välisfirmad kasutades läänes toodetud konteinereid

  18. Ene-Liis Semper : Kohalolu piiritsoonis = Presence in the border zone / Anu Allas

    Index Scriptorium Estoniae

    Allas, Anu, 1977-

    2007-01-01

    Teatri- ja videokunstnik Ene-Liis Semperi peamiselt 1990-ndate aastate videotest, mis on valdavalt rõhutatult lavastuslikud, paisutatult sümbolistlikud või kus on esitatud piirsituatsioone, ahistust ning selle teadlikku eksponeerimist väljakutsena publikule. Iseennast paljastades, alandades ja ohtu seades jääb kunstnik enamasti jahedalt distantseerituks, publikule jääb aga arusaamatuks, kas tegemist on ohvri, kangelanna või osava mänguriga

  19. Euroopa kultuuripealinn Tallinn 2011 paneb PÖFF-ile õla alla

    Index Scriptorium Estoniae

    2011-01-01

    15. Pimedate Ööde Filmifestivali ja Euroopa Kultuuripealinna Tallinn 2011 koostöös alguse saanud noortele animavallas tegutsevatele professionaalidele mõeldud koolitussarjast AnimaCampus, rahvusvahelise filmituru Black Market ja programmi "60 sekundit üksindust aastal Null" toetamisest

  20. Tööjõu probleem pole laologistika valdkonnas enam nii terav / Roger Allas

    Index Scriptorium Estoniae

    Allas, Roger

    2008-01-01

    Ilmunud ka: Delovõje Vedomosti 12. märts lk. 25. Konverentsil Laoseis 2008 nenditi, et tööjõu olukorra paranemist on soosinud vaikne seis kinnisvaraturul ja majanduse stabiliseerumine, mistõttu on tekkinud turule hulganisti töökäsi, kes varem tegutsesid ehituse alal

  1. Libakütus viis eduka firma luubi alla / Virkko Lepassalu

    Index Scriptorium Estoniae

    Lepassalu, Virkko, 1971-

    2003-01-01

    Tolliamet algatas uurimise firma Kvare Petroleum suhtes, kuna kahtlustab ettevõtet kavatsuses panna jaemüüki 400 000 liitrit kvaliteedinõuetele mittevastavat kütust. Diagramm: Kvare Petroleum kõige kiiremini arenevate kütusefirmade hulgas. Vt. samas: TÜ Bitest sattus teist korda kahtlast päritolu kütuse hoiupaigaks

  2. Manhattanile autoga minek läheb maksu alla / Neeme Raud

    Index Scriptorium Estoniae

    Raud, Neeme, 1969-

    2007-01-01

    New Yorgis toimunud maailma suurlinnajuhtide kliimafoorumil propageeris Londoni linnapea Ken Livingston linnasüdametesse sissesõidutasu kehtestamist, New Yorgi meer Michael Bloomberg plaanib kehtestada Manhattanile sissesõidu eest kaheksadollarilise tasu. Lisa: Suurlinnad autosid piiramas

  3. Organizzazioni femminili e accesso alla política in Conchucos, Perú

    OpenAIRE

    Venturoli, S.

    2010-01-01

    In this paper we propose to delineate the educational path to political action that a rural community in the Peruvian Andes, Ancash region, is developing. What are the social and cultural conditions necessary for a policy of decentralization to obtain greater participation and interaction between different levels of power? Witch is the necessary learning process? and at what price doubly discriminated areas of society, such as women of low social class and educational level, and Quechua speak...

  4. Dall'atomismo sociale alla società ecologica. L'etica di Murray Bookchin

    Directory of Open Access Journals (Sweden)

    Alessandra Cannillo

    2011-01-01

    Full Text Available From Social Atomism to Ecological Society. Murray Bookchin's Ethics - Murray Bookchin examines the relation between nature and society in broader philosophical and ethical terms. In his thinking social and ecological themes interact on different levels, with a single purpouse: to identify the caises of the contemporary social crisis, from which the ecological crisis has arisen, and to find possible solutions, modeling morality on nature, to lay the foudations of an "ecological society" or, better, a "social ecology".

  5. Evoluzione dell'edificato residenziale in rapporto alla pericolosità sismica

    Directory of Open Access Journals (Sweden)

    Juri Corradi

    2015-12-01

    The comparison between various types of information was carry out using GIS software, in particular "overlay" functions allows us to assign to each enumeration area the level of seismic hazard. Moreover, the use of microdata at the enumeration area level, it allows the calculation of the vulnerability indicators, grouped by time of construction and by population density, in seismic hazard classes at the municipal level.

  6. Legami di coppia e affettività. Dall’amore romantico alla relazione pura

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    Rita Biancheri

    2012-03-01

    Full Text Available In this paper we examine the changes that have characterized bonds between couples and affectivity, through the contributions of classical as well as contemporary sociologists. Starting from the family as a social institution, we go on to an examination of transformations in intimacy and in relations of negotiation, with an eye towards interdisciplinary contributions.

  7. Coding alla scuola dell’infanzia con docente esperto della scuola primaria

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    Giovanni Nulli

    2017-11-01

    Full Text Available La sperimentazione qui presentata, parte del progetto Coding@scuola, contenuto nel Piano Triennale delle Attività 2015-2017 di Indire, ha l’obiettivo di studiare percorsi di pensiero computazionale nell’ultimo anno della scuola dell’infanzia in una prospettiva di verticalizzazione e focalizzazione sulle aree delle Indicazioni Nazionali per il Primo Ciclo.

  8. Tšehhi asepeaminister on sattunud mitme tule alla / Allan Espenberg

    Index Scriptorium Estoniae

    Espenberg, Allan

    2007-01-01

    Tšehhi asepeaminister ja regionaalarenguminister Jiri Cuneki mustlaste vastu suunatud mõtteavaldused. Asepeaministrit süüdistatakse ka poole miljoni kroonise altkäemaksu vastuvõtmises H&B Reali nimeliselt kinnisvarafirmalt 2002. a.

  9. Organizzazioni femminili e accesso alla política in Conchucos, Perú

    Directory of Open Access Journals (Sweden)

    Sofia Venturoli

    2010-12-01

    Full Text Available In this paper we propose to delineate the educational path to political action that a rural community in the Peruvian Andes, Ancash region, is developing. What are the social and cultural conditions necessary for a policy of decentralization to obtain greater participation and interaction between different levels of power? Witch is the necessary learning process? and at what price doubly discriminated areas of society, such as women of low social class and educational level, and Quechua speaking, must take to achieve real social inclusion and self-determination? What are the dynamics in place and the tools used by the women of the community to gain more weight in politics and decision-making and how they fit into the socio-cultural reality of rural Andean?

  10. Kuusalus saab rattad alla autotreileritööstus / Peep Talimaa

    Index Scriptorium Estoniae

    Talimaa, Peep

    2008-01-01

    OÜ-le Trucks & Trailers kuuluvast Kuusalu treileritehasest. Lisa: Kuusalu treileritehase ajalugu ja eellugu; Autotreileri valmimine; Üldandmeid treilerite kohta; Kuusalu treileritehase ajalugu ja eellugu

  11. GEOmedia su Marte Uno sguardo alla nuova cartografia di un pianeta

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    Renzo Carlucci

    2007-03-01

    Full Text Available L’esplorazione del sistema solare e la necessità di realizzare una cartografia, strumento indispensabile per qualsiasi tipo di indagine il genere umano abbia oggi in mente, ci porta ad affrontare il problema dell’estensione dei sistemi di riferimento, partendo dal presupposto che la Terra non è più ormai il solo oggetto dell’esplorazione geografica.

  12. Dalle Ande alla Val Padana, dalle famiglie alle culture: note su un seminario di Igino Bozzetto

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    Massimo Giuliani

    2004-06-01

    Full Text Available Il seminario di Igino Bozzetto sul ricongiungimento familiare diventa opportunità per riflettere sulle connessioni tra cornice sistemica - nella variante che conosciamo come cibernetica di secondo ordine - e studio della comunicazione interculturale. Bozzetto mostra come i concetti chiave dell'approccio sistemico nella sua declinazione sociocostruzionista trovano applicazione nel delicato lavoro con le famiglie immigrate ed i minori. In particolare la polifonia, che caratterizza l'approccio sistemico, diventa la chiave per entrare in relazione con l'altro, una cornice per la convivenza di punti di vista e per l'esercizio della curiosità.

  13. Näljane Wal-Mart tahab ka smiley alla kugistada / Erik Aru

    Index Scriptorium Estoniae

    Aru, Erik

    2006-01-01

    USA jaekaubanduskett Wal-Mart tahab oma kaubamärgina registreerida smiley' - kollase naerunäo kujutise. Smiley' leiutajaks peab end Suurbritannias asuva ühemehefirma SmileyWorld omanik Franklin Loufrani. Lisa: Wal-Mart üritab jõukamaid kundesid meelitada. Tabel: Wal-Mart

  14. Itaallased otsustasid suurärimees Berlusconi valitsemise alla naasta / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2008-01-01

    Itaalia erakorralised parlamendivalimised võitis juba kolmandat korda endine peaminister Silvio Berlusconi. Diagramm: Berlusconi miljardid. Lisa: Võimule aitas meediarusikas; Jõukuse allikas on teadmata

  15. Le antologie e le grandi opere come contributi alla costruzione dei canoni

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    Remo Ceserani

    2017-06-01

    Full Text Available In this paper, Remo Ceserani reflects upon the notions of canon and anthology in relation to the institutions behind them. After a short premise in which the traditional role of Church and school in the process of canonization is taken into account, the discussion moves to the present age, focusing on the idea of canon that lies at the basis of both North-American and Italian anthologies. In the former case, Ceserani highlights how the emergence of world literature has led to revise the structure of anthologies; in the latter case, the author argues that the canon mutuated from the work of Francesco De Sanctis still functions as the main source for many anthologies. He then concludes by stating that a thematical approach could constitute an alternative structuring criterion for a scholastic anthology.

  16. Le antologie e le grandi opere come contributi alla costruzione dei canoni

    OpenAIRE

    Ceserani, Remo

    2017-01-01

    In this paper, Remo Ceserani reflects upon the notions of canon and anthology in relation to the institutions behind them. After a short premise in which the traditional role of Church and school in the process of canonization is taken into account, the discussion moves to the present age, focusing on the idea of canon that lies at the basis of both North-American and Italian anthologies. In the former case, Ceserani highlights how the emergence of world literature has led to revise the struc...

  17. Dali ärijuht võeti võltsijana vahi alla

    Index Scriptorium Estoniae

    2000-01-01

    Hispaania politsei vahistas Salvador Dali sekretäri ja ärijuhi Peter Moore'i, süüdistades teda Dali litograafiate võltsingute organiseeritud müügis. Moore'ile kuulunud laohoonest Cadaquesis leidis politsei 80 Dali litokivi.

  18. Eesti tipprallimehed koondusid ühise kaubamärgi alla / Peep Pahv

    Index Scriptorium Estoniae

    Pahv, Peep, 1970-

    2008-01-01

    WRC-sarjas osalevad Urmo Aava ja Kuldar Sikk, PWRC-sarjas startivad Martin Rauam ja Silver Kütt ning juunioride sarjas sõitvad Jaan Mölder ja kaardilugeja Frederic Miclotte on tänavusteks võistlusteks registreerinud võistkonna World Rally Team Estonia

  19. Alla ricerca di un canone europeo tra plurilinguismo e multiculturalità

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    Michaela Böhmig

    2004-12-01

    Full Text Available In Search of a European Canon between Multilingualism and Multiculturalism The article's aim is to point out a series of problems related to 1 the “new” Europe, 2 the “European” canon, and 3 multilingualism and multiculturalism. The author moves from the evidence that the political priority of redesigning the enlarged European Union’s new borders involves the risk to let aside the equally or even more important task to redefine the “European” roots and to establish shared cultural values, and she raises the question of what is to be considered “Europe” and “European”. Reviewing the fundamental works, which in an centripetal effort try to collect the basic myths and themes of the Western and/or European cultural space, such as Stoffe der Weltliteratur by Elisabeth Frenzel (Stuttgart 19887, Dictionnaire des Mythes Littéraires, edited by Pierre Brunel (Paris 1988, The Western Canon by Harold Bloom (New York 1994, and Europa: tema y variaciones (Madrid 2000 by José Antonio Jáuregui, the author remarks that the contribution of the Eastern European countries to what should be a common inheritance seems to be very small or even non-existent. Since this disproportion cannot be ascribed to an inadequate cultural production, the only explanation remains a prevailing one-way influence from West to East . and not vice versa . and a consequent one-sided perception by European scholars. In order to establish a complete “European” canon, it is therefore necessary to enlarge the borders toward East and to include the Slavic area. An opposite approach can be observed in language policy, which in a centrifugal effort, due to the objective difficulty to choose or produce a common European language, insists on an equal status for all European languages, from the major national languages to those of ethnic minorities, all to be preserved by means of “positive discrimination”. Besides the difficulty to govern a federation of countries with 11 official languages and over 40 idioms of ethnic minorities, there remains the evident contradiction of considering “European” all the languages included within the borders of the enlarged European Union, whereas a language as Russian, which has a weight both as a cultural and a vehicular language, will be considered a language of an ethnic minority in some peripheral states, such as the Baltic countries. On the way towards a “new” Europe, with cultural relativism on the one side and Realpolitik on the other, one should not leave centuries of historic development and cultural traditions out of consideration.

  20. L'engagement del consumatore verso la marca: uno sguardo non convenzionale alla comunicazione

    OpenAIRE

    Franco Valerio

    2011-01-01

    Current rate of change is way faster than rate of understanding, adoption and implementation by brands and communication agencies. We learn from the recent present and transform empirical learnings into best practice and approaches for tomorrow's communication challenges. The way to connect, interact and build a relationship between brands and consumers is undergoing deep and disruptive changes. People relate to brands differently. Actually: from now on people will be able to make their thoug...

  1. "Tanto Necesitamos De Aqui Como Necesitamos De Alla": "Leer Juntas" among Mexican Transnational Mothers and Daughters

    Science.gov (United States)

    de la Piedra, Maria Teresa

    2011-01-01

    This paper presents part of the results of a qualitative study about literacy practices of Mexican transnational mothers, who live in and frequently cross the border between two countries (the United States and Mexico). Drawing on sociocultural approaches to literacy and literature on transnationalism, I analyze one practice: "leer…

  2. Dal sultanato alla monarchia: fondamenti ideologici e simbolici del Marocco post-coloniale

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    Barbara De Poli

    2013-12-01

    Full Text Available This paper highlights some key aspects of the construction of the modern Morocco, during a nation building process which affects the Arab countries during the first half of the twentieth century. In particular, it will focus on the transition from sultanate to constitutional monarchy, which created changes in the institutional order and implied the adjustment of the symbolic capital investing the local Power, with an evident ‘invention of tradition’. This process is essential to the axial role which the Alawite dynasty played during the anticolonial struggle by sustaining the nationalist movements in order to pursue the political hegemony in the post-independence and ensure a strong continuity.

  3. Fukushima aruanne võtab luubi alla ohutusküsimused / Kadri Veermäe

    Index Scriptorium Estoniae

    Veermäe, Kadri

    2011-01-01

    Rahvusvaheline Aatomienergiaagentuur (IAEA) on avaldanud esialgse raporti Fukushima tuumaelektrijaamaga seotud ohutusküsimuste kohta, milles rõhutati vajadust olla valmis äärmuslikeks loodusoludeks. Tuumaeksperdid on külastanud kolme Jaapani tuumaelektrijaama, et selgitada, millised on Fukushima õnnetuse õppetunnid. Euroopa Liidu murest maailma ohtlikemaks peetud Armeenia tuumaelektrijaama Metsamori pärast

  4. Dalla grammatica alla pratica della lingua. Approcci linguistici medievali e umanistici

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    Minne Gerben de Boer

    2016-09-01

    Full Text Available Recensione diLa pratica e la grammatica. Problemi, modelli e percorsi di formazione linguistica tra Duecento e Cinquecento, a cura di Franco Pierno e Giuseppe Polimeni, Paris, Classiques Garnier, 2014 (numero speciale di Cahiers de recherches médiévales et humanistes-Journal of Medieval and Humanistic Studies, 2/28, pp. 13-234, ISBN: 9782812445675.

  5. WTO kokkulepe viib piima hinna alla / Silja Lättemäe

    Index Scriptorium Estoniae

    Lättemäe, Silja, 1952-

    2005-01-01

    18. detsembril 2005. a. Hongkongis toimunud Maailma Kaubandusorganisatsiooni (WTO) tippkohtumisel saavutatud põllumajanduse-alaseid kokkuleppeid kommenteerib põllumajandusministeeriumi asekantsler Andres Oopkaup

  6. “Troppo vicini”. Letture della catastrofe prossima nel pensiero meridionale alla fine del XVIII secolo

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    Monica Riccio

    2013-10-01

    Full Text Available “Too close”. Reading nearby catastrophes in Southern Italian thought at the end of the XVIIIth century. This paper analyses the intersections between the ideas of catastrophe and revolution in Southern Italian writers at the end of the XVIIIth century, focusing on those who operated in the proximity of a natural or political upheaval. The way in which this proximity modifies the value of the concept of catastrophe is well shown by the writings of the “observers” of the 1783 earthquake in Calabria and Messina and by their effort to offer a testimony and narrate the catastrophe at present tense.

  7. Palgaralli jätkumine viib konkurentsivõime alla / Vello Kutsar

    Index Scriptorium Estoniae

    Kutsar, Vello

    2006-01-01

    Autori hinnangul ületab tänavuse aasta lõpuks keskmine palk 9 000 krooni piiri. Joonised: 1. Brutopalga kasvud protsentides maakonniti ja nende hälve protsendipunktides 2006. a. I ja II kvartalis, võrreldes eelmise aasta sama perioodiga; 2. Brutopalga 2006. a. I ja II kv. kasvud (%) tegevusalade lõikes, võrreldes eelmise aasta vastava perioodiga. Tabelid: 1. Keskmine brutopalk maakonniti (kr.) ja selle kasv 2006. a., võrreldes vastava perioodiga eelmisel aastal (%); 2. Keskmine brutopalk tegevusalade lõikes ja selle kasv 2006. a., võrreldes vastava perioodiga eelmisel aastal (%); 3. Keskmine palk (EEK)

  8. La legge della Regione Lombardia sull’edilizia di culto alla prova della giurisprudenza amministrativa

    Directory of Open Access Journals (Sweden)

    Natascia Marchei

    2014-03-01

    Full Text Available contributo sottoposto a valutazioneSOMMARIO: 1. L’edilizia di culto tra tutela della libertà religiosa e governo del territorio: la legge n. 12 del 2005 della Regione Lombardia - 2. segue: Gli interventi “correttivi” della legge regionale n. 12 del 2005 - 3. La giurisprudenza amministrativa sul cambio di destinazione d’uso tra Tribunali amministrativi e Consiglio di Stato: la prevalenza del rispetto della normativa urbanistica sul diritto di libertà religiosa 4. L’interpretazione del requisito della necessaria “convenzione” con il comune: l’attuazione giurisprudenziale del diritto di libertà religiosa - 5. Brevi conclusioni.

  9. Carrara e le sue cave. Alla scoperta dei paesaggi del marmo

    Directory of Open Access Journals (Sweden)

    Francesco Alberti

    2015-11-01

    Full Text Available The article describes the strategic master plan drawn in 2007 by P. Giorgieri and F. Alberti, along with a marketing study by SL&A (Rome, for promoting tourism through the places of white marble in Carrara - quarries, sculpture ateliers, exhibition spaces, villages and trails of old quarries, etc.. The proposal is part of the Integrated Plan for Urban Sustainable Development (PIUSS presented with success by the Municipality to the Region Tuscany in 2010, for the allocation of the European structural funds. The plan is structured on six touristic itineraries, some of which follow the routes of the old “Marble Railway”, linking the town center with the extraction areas (with their active or dismissed quarries belonging to different times and the footpaths of the Park of the Apuan Alps.

  10. Come pecore al macello? Ebrei nella Shoah e reazioni alla persecuzione

    Directory of Open Access Journals (Sweden)

    Marcella Hannà Ravenna

    2014-04-01

    Full Text Available Like Sheep to the Slaughter? Jews in the Shoah and Reactions to Persecution – While most psychosocial analyses of the Shoah focus on psychological issues relating to the behavior of the perpetrators, this study examines similar issues in relation to the victims. Eschewing from a homogeneous representation of Jews as going to their death like sheep to the slaughter, the aim here is to characterize the psychology of the victims and their daily actions in the face of persecution. The content analysis performed on a pertinent body of contributions from the historical, philosophical, sociological, psychological and memory literatures – has identified the contribution of numerous factors. These factors do not so much relate to particular characteristics of the victims themselves as to relationships between members of the minority and majority over the course of time. Moreover, they related to strategies employed by the victims to cope with ongoing persecution and specific actions of diversion by their executioners. Mostly neglected by post war historiography, this evidence for a marked reliance on “unarmed reactions”, further contributes to articulating the representation of the victims.

  11. Dalla politica alla gestione del bene comune. L’esempio del teatro Valle a Roma

    Directory of Open Access Journals (Sweden)

    Alice Furlan

    2015-11-01

    Full Text Available The concept of common good could be declined in three major points: 1 the theft of the good itself from the profit mindset; 2 the creation of a link between the community and the good; 3 the creation of a new management form, neither public nor private, which knows the capacity of the good itself. From the analysis of the schedule published by MiBAC, it is clear that there is a lack of founds addressed to the artistic research. The situation that occurs nowadays is imposing the necessity of identifying another kind of development model. I took, as a research topic, Teatro Valle, which is one of the most important case in the Italian national context. The management of the entire structure undergoes through the principles of non-rivalry, non-exclusion and self-governance. The strongest points of this model are: the idea of an alternative management and the creation of synergies between several cultural movements.The theatre itself has been seeing as a multi-functional location: there are lots of performances flanked by debates, conferences, talks, and other initiatives. Another important aspect is the great visibility that the experience has been receiving through the years. However it is necessary to underline that the building, which is a private property, lives in a condition of lawlessness because it has been occupied. Moreover Teatro Valle has been accused of unfair competition by other cultural spaces. Since the culture is the common thread that helps us to uphold our identity, the common goods help us to recognize ourselves and state our fundamental rights.

  12. influences of the exotic in maria messina: i racconti di cismè and alla ...

    African Journals Online (AJOL)

    User

    frame-story that all the exoticism is gathered: the remaining stories ...... regarded as Mariucca's portal to the outside world, to life. Irwin's .... century opulence and authentically spare Japanese design, not quite a true Japanese ambience,.

  13. Balans mellan arbete och familjeliv : Ett vinnande koncept för alla

    OpenAIRE

    Holmgren, Viktor; Ajena, David

    2012-01-01

    Under de senaste årtionden har en stor förändring skett hos familjers olika sätt att förhålla sig till arbetslivet. Den traditionella arbetsdagen på 8-timmar är inte längre normen, och den framväxande informations- och kommunikations teknologin gör att en anställd kan få tillgång till allt arbete 24/7. En följd av dessa förändringar är att efterfrågan på familjerelaterande- och hushållsnäratjänster har ökat både för män och kvinnor. Rapporten har visat forskning och studier som påvisar att de...

  14. Dall’ermeneutica del sé alla politica di noi stessi

    Directory of Open Access Journals (Sweden)

    Daniele Lorenzini

    2013-03-01

    Full Text Available This article tries to highlight the explicit political aim and the importance for our present of the thought of the «late» Michel Foucault. Through the analysis of the role that truth plays in the pagan and Christian techniques of the self, it opposes a truth that we have to discover in ourselves in order to refuse it (Christianity or to adhere to it (ethics of authenticity to a truth conceived as a force of transformation of logos into ethos, of the discourse into a way of life.

  15. Festivalipäevik Kanutist II / Anu Allas, Margit Tõnson, Margaret Tali

    Index Scriptorium Estoniae

    Allas, Anu, 1977-

    2005-01-01

    Tallinnas Kanuti Gildi saalis kestab 2.-24. novembrini 2005 a. "Continental Breakfast" Tallinn ehk rahvusvaheline NU Performance festival. 9. novembril esineb BabaLAN (Vlado Gotvan Repnik, Sloveenia ) multimeedia-performance'iga. Eva Meyer Kelleri performance "Surm on kindel" (esitaja Irina Müller)

  16. Festivalipäevik III / Margaret Tali, Anu Allas, Margit Tõnson...[jt.

    Index Scriptorium Estoniae

    2005-01-01

    Rahvusvaheline NU Performance festival "Continental Breakfast" Tallinnas Kanuti Gildi saalis 2.-24. nov. 2005. Hollandlase Kim H. Veltmani loengu formaadis performance "World tree". Katrin Essensoni performance "Designed to make difference". Gob Squad (Saksamaa/Inglismaa) "Super Night Shot".

  17. Dal manichino alla real doll. La bambola nella visualità contemporanea

    Directory of Open Access Journals (Sweden)

    Alessandra Olivares

    2014-12-01

    Full Text Available The doll, in its various manifestations of substitute of real woman for at least forty years is a subject at the heart of poetics of many artists that through it convey stereotypes, ideas and experiences related to the feminine universe. And yet over time is profoundly changed the way of understanding and representing this object, that is one of the most discussed and controversial of our time for the disturbing familiarity that does not leave indifferent those who observe. Particularly in the case of real dolls or sex dolls, so likely and cured in the minimums details to seem real. Disregarding the controversies and aspects related to the questionable erotic business that these dolls are part, what cannot be ignored is that more and more often they are at the heart of art projects that seem real psychological studies around the emotional sphere of the individual.There are many artists who through a skilful use of the photographic instrument, combined with set designed down to the smallest details, accessories and poses, committed their search around the possibility to transpire emotions from a subject who notoriously cannot try them.But why is it so important to provide with a soul these inanimate bodies? Why do we so much need of these surrogates to bring out human feelings and emotions?After excessive and obsessive use of the poetics of the doll in the Surrealism, starting in the 1970s, this subject is recovered and used as a kind of mirror to reflect the process of manipulation and reification of a body increasingly artificial, and advances in plastic surgery and genetic engineering as the crucial stages of the construction of a man-machine-thing. Among the exponents of this art, notoriously defined post-human, there are the pioneer Helmut Newton, followed by Cindy Sherman, Nick Knight, Charles Ray and Vanessa Beecroft, just to name a few.What however that is investigated is the inversion of march that we see in many artists. In the poetics of Laurie Simmons, Beatrice Morabito, Azusa Itagaki and Elena Dorfman, emerge the urgency to recover humanity and vulnerability, peculiar features that mass-medial messages have for long time tried to cancel in the name of depersonalizing ratification and culture of success at all costs. That’s how the doll from the classic stereotype of women-object, of a body increasingly manipulated and artificial, becomes a subject to love and care for or to share real experiences and emotions. Reflection of a society suffering from autism and narcissism?

  18. STRATEGI PEMERINTAH DAERAH DALAM PENGEMBANGAN PASAR AGRIBISNIS DI DESA SUMILLAN KECAMATAN ALLA KABUPATEN ENREKANG

    Directory of Open Access Journals (Sweden)

    Muhammad Syukur

    2012-04-01

    Full Text Available The purpose of this study is to determine the Local Government Strategy for the Development of Agribusiness Market in the Simillan Village District of Allla, Regency of Enrekang. The method used is qualitative. Data were collected using instruments such as: observation, documentation and developed with interviews with informants. Technical analysis of the data used in this study is a model of interactive analysis, namely: data collection, data reduction, data serving and withdrawal conclusions. The validity of the data in this study examined using triangulation techniques. These results indicate that counseling and assistance to agricultural and plantation actors government acting through the provision of guidance and direction that intensive and effective to the community as an effort to develop business systems in marketing promotion of agricultural products, the government plays as an agent that accelerates the development of regional potential strategies local governments in the development of the excellent potential in this case of vegetables and fruits by using SWOT analysis so far has been the maximum in the running srtategi maximum for use on the public especially in agriculture and plantations.   Tujuan penelitian ini yaitu untuk mengetahui Strategi Pemerintah Daerah dalam Pengembangan Pasar Agribisnis di Desa Sumillan Kecamatan Allla Kabupaten Enrekang. Metode penelitian yang digunakan adalah kualitatif. Data yang dikumpulkan dengan menggunakan instrumen berupa observasi, dokumentasi dan dikembangkan dengan wawancara terhadap informan. Tehnik analisis data yang digunakan dalam penelitian ini adalah model analisa interaktif, yaitu: Pengumpulan Data, Reduksi Data, Sajian Data, dan Penarikan Simpulan. Keabsahan data dalam penelitian ini diperiksa dengan menggunakan teknik triangulasi. Hasil penelitian ini menunjukan bahwa Penyuluhan dan pendampingan kepada pelaku pertanian dan perkebunan pemerintah berperan melalui pemberian bimbingan dan pengarahan yang intensif dan efektif kepada masyarakat sebagai upaya pengembangan sistem bisnis dalam pemasaran promosi hasil pertanian, pemerintah berposisi sebagai agen yang mempercepat pengembangan potensi daerah Strategi pemerintah daerah dalam pengembangan potensi unggulan dalam hal ini sayur dan buah-buahan dengan menggunakan analisis SWOT yang sejauh ini telah maksimal dalam menjalankan srtategi yang m maksimal untuk digunakan pada masyarakat apalagi dalam bidang pertanian dan perkebunaan.

  19. Kempsupotist alla lastud hiir räägib eesti keelt / Triin Tael

    Index Scriptorium Estoniae

    Tael, Triin

    2006-01-01

    Animakomöödia "Vesi peale" ("Flushed Away") : režissöörid David Bowers, Sam Fell : eestikeelse dublaazhi režissöör Janno Põldma : rotipoiss Roddy rolli dubleerija Jaak Prints : Ameerika Ühendriigid - Suurbritannia 2006 (stuudiod DreamWorks ja Aardman)

  20. Hourly metering for everybody. Benefits, regulations and economy; Timmaetning foer alla. Nytta, regelverk och ekonomi

    Energy Technology Data Exchange (ETDEWEB)

    Badano, Andrea; Fritz, Peter; Goeransson, Anders; Linden, Magnus

    2007-12-15

    Today extensive investments in new modern electricity meters (AMR systems) are taking place in Sweden. The main reason for these investments is the new requirements on monthly meter readings, but these systems can generally do a lot more. Other Market Design projects have identified the need for more demand response in the electricity market and the important role of hourly settlement instead of profiling. With present rules and regulation there is an obvious risk that the new AMR technology will not be used to its full socio-economical potential. A survey made in this study implies that 90 % of the meters in which grid companies are investing today, make it possible to both register and store hourly meter values. A considerably lower share of the new systems will fully meet the demands of hourly settlement. Hourly settlement is both individually and collectively an advantage for the customer. Better tariffs and means of control should lead to a more cost-effective power system and in the long term also give lower electricity prices and higher security of supply. Customers can be well paid when decreasing electricity consumption when electricity price is high. Better statistics and follow-up will also lead to lower electricity consumption. Consequently, customers can make great use of hourly meter readings and management at hour-based level. At the same time, care must be taken how these possibilities are presented for the customers. They must be given information which is brought into line with each costumer's individual needs as far as possible. For power suppliers, hourly settlement would mean possibilities to offer new attractive tariffs to customers. It would give customers opportunities to reduce their electricity consumption and at the same time reduce risk exposure for the power supplier. With the power supplier and the customer having this knowledge about his electricity consumption, the power supplier is able to develop new services such as helping the costumer to analyze and influence his electricity consumption. Through clever grid tariffs, grid capacity can be used more efficiently. Also, management and surveillance can be offered to customers in order to optimize their electricity consumption both against the grid tariff and retail price. It also opens up for earning money through new kinds of services offered by the grid companies. It is then very important, however, that these services are developed in such a way so that the competition between power suppliers is not affected. To make grid companies voluntarily switch to hourly settlement for all its customers, changes in today's regulations are needed. In this study several of these requirements have been identified. In another ongoing Market Design project, 'Feasibility study for costumer flexibility', more information will be added for estimating what economical and environmental advantages hourly meter readings, new tariffs and new business opportunities can give

  1. Dal dissenso alla rivoluzione: satira e potere nel mondo arabo contemporaneo

    Directory of Open Access Journals (Sweden)

    Barbara De Poli

    2012-10-01

    Full Text Available The satire against Authority can provide a special understanding of contemporary history of Arab countries, especially exploring humour expressions before, during and after the 2011 revolts. After an historical review of satirical expressions in the MENA region in XX century, this study investigate the role that humour and satire played in particular during the Tunisian and Egyptian revolts. Even during the rough and brutal moments of the riots, Tunisians and Egyptians could laugh at the fading power of Ben Alì and Mubarak, testifying their pungent derision of the regimes. Their fall has therefore consented a wider degree of freedom of expression including various forms of humour, chiefly satirical, that nowadays, especially on web sites, provide a parallel overview of recent events.

  2. Garibaldi e l'epopea garibaldina nel cinema muto italiano. Dalle origini alla I guerra mondiale

    Directory of Open Access Journals (Sweden)

    Giovanni Lasi

    2011-03-01

    Full Text Available The first film producted by an italian studio was "La presa di Roma - 20 settembre 1870" (Albertini & Santoni, 1905 and the Italian Risorgimento will continue to be one of the most favoured subjects of italian cinematography. In the period of silent screen films, between 1905 and 1927, aproximately 60 films were produced in Italy concerning the Risorgimento, of which at least 30 were regarding Garibaldi and his epic actions. Even in the cinema, Garibaldi continued to be the most representative and emblematic figure of the Risorgimento, and his popularity is often exploited in misleading ways by the figures of power during the first decades of the twentieth century to ideologize the figure of Garibaldi, still through cinema.

  3. Le ultime tecnologie hanno aiutato i primi soccorsi alla Costa Concordia

    Directory of Open Access Journals (Sweden)

    Andrea Faccioli

    2012-04-01

    Thanks to the Geomatics, the Costa Concordia operations are conducted in conditions of extreme security to protect both the lives of rescue workers and the delicate environment.All technologies involved (Lidar, Multibeam, GNSS, INS, ecc…, while having a primary role in real life, have always worked quietly behind the scenes.

  4. Hannes Tamjärv pani sojatehasele õla alla / Signe Kalberg

    Index Scriptorium Estoniae

    Kalberg, Signe, 1959-

    2006-01-01

    Soya Foods Baltic hakkab tootmist arendama Järvamaal Kareda vallas, eesmärk on varuda tulevikus sojauba Eesti põllumeestelt. Sojapiima valmistamisest. OÜ Lisa: Ostjate huvi sojatootjate vastu kasvab

  5. Il contributo dell'Ecu alla stabilità dei cambi: un ulteriore commento

    Directory of Open Access Journals (Sweden)

    F. FORNARI

    2013-10-01

    Full Text Available Following recent articles by Jager and de Jong on the one hand, and Sarcinelli on the other, the present work offers additional analysis on the topic of the ECU and exchange-rate stability.  The author shows that the effect of the ECU on exchange-rate stability mainly depends on the presence of arbitrage activity, i.e. the flows of national currencies which the ECU market gives rise to in order to counterbalance an excess demand for Ecus on the Euromarket. When arbitrage is introduced into the analysis, the relationship between the dollar and mark and pound gets worse (so creating instability whereas the contribution of the ECU to European currencies’ stability remains positive, though reduced.  JEL Codes: F15, F36, E42 

  6. Il destino dell’uomo alla fine dello spazio [… e del tempo

    Directory of Open Access Journals (Sweden)

    GIANNINI, GIANLUCA

    2016-06-01

    Full Text Available Human Destiny at the End of Space […and Time] The common idea of time and space that we still have is surely due to Newton. Space, similar to a plank, is the entities on which and within take place all facts of the world, while time is the fundamental reason of self-identification and self-comprehension. With Einstein come to lay the foundations for the revolutionary concept whereby space and time do not exist. All this – and it is the fundamental reason for the unusual form of connection between physics and philosophy – can achieve extraordinary, speculative, acquisitions: a the end of traditional metaphysics; b each time this make-space, how about the existence of the entities/objects only as of the effective possibility (that is establishing actually in their interrelationship, is preceded by a radical absence of being: there is existence only in the effectiveness of all this; c that the Being of Western Tradition, being no longer something of a pre-writable in its pre-existence, being instead led, each time, of probabilistic, not causal, interrelations, opens to a new meaning of ontology as de-ontology. A de-ontology where being can be said only closed in the logos, in this-logos-here as the way of a strategy of man in his interrelation with the world.

  7. La Fiat e la AutoVAZ di Togliatti. Alla ricerca del fordismo perduto

    Directory of Open Access Journals (Sweden)

    Valentina Fava

    2013-01-01

    Full Text Available In 1966 Vittorio Valletta, Fiat president, and the representatives of the Soviet Government signed the agreement that led to the building of the VAZ -Volzhsky Avtomobilny Zavod, a gigantic automobile plant. The Fiat-Soviet plant fostered the entrance of the Soviet Union (USSR in the «Automotive Century» and gave place to the first massive East-West transfer of technology and knowledge in the automobile sector of the century. The paper underscores the reasons of Fiat interest in the Soviet market, underlying how the deal had been coordinated with the Italian entrepreneurial elites and partially backed by the American Administration. Furthermore, the paper sheds light on the channels that Fiat used to enter in the Soviet market - focusing especially Fiat's agent, Piero Savoretti.

  8. Legami 2.0. Il genere alla prova della contemporaneità

    Directory of Open Access Journals (Sweden)

    Redazione Camera blu

    2016-12-01

    Full Text Available Numero a cura di Anna Gargiulo. Il numero guarda alle trasformazioni che attengono al genere femminile che vanno oggi configurandosi nel virtuale, nei media, nelle sfide della società contemporanea rivolte ai corpi, alle famiglie, ai sistemi accademici. Si parte dai legami, dai link, che tanto possono connettere paesi e generazioni quanto legare oppressivamente l’altro a sé.

  9. Kapoyt/blu: alla scoperta della storia armena di un colore

    Directory of Open Access Journals (Sweden)

    Marco Bais

    2012-10-01

    Full Text Available The study begins with an analysis of the semantics of the Armenian word kapoyt, blue, taking into account its different uses in Armenian literature, e.g. its possible connection with natural elements (lakes, seas, sky, etc., clothes, diseases, precious stones, and toponyms. Great attention has been paid to the metaphorical meanings of kapoyt in Armenian tradition, which are related with feelings such as envy, jealousy, and sorrow. The second part of the study deals with the colour blue as a mean of artistic expression. On the one hand, the symbolism of blue has been investigated through the reflection on the aesthetics of colour found in the works of some Armenian Christian authors of the Middle Ages. On the other, we analyse different types of pigment used by Armenian artists in different times and in different schools, according to the information of ancient handbooks on colour production, and on the basis of data concerning the trade in colouring matters.

  10. Dalla «più difforme congerie di oggetti» ad un «perfetto ambiente spirituale» per l’opera d’arte. L’allestimento del Museo Nazionale di Palermo alla fine degli anni Venti del Novecento / From the “più difforme congerie di oggetti” (most dissimilar jumble of objects to a “perfetto ambiente spirituale” (perfect spiritual environment for the work of art. The display of Palermo National Museum at the end of the 1920s

    Directory of Open Access Journals (Sweden)

    Ivana Bruno

    2016-12-01

    Full Text Available Nel panorama dei musei italiani del terzo decennio del Novecento, delineato da Francesco Pellati nella Enquête internationale sur la réforme des galeries publiques, si distingue il Museo Nazionale di Palermo, dove la giovane ispettrice Maria Accascina aveva appena completato il riordinamento e l’allestimento della sezione di arte medievale e moderna. La storica dell’arte, allieva di Adolfo Venturi, aveva elaborato un progetto di restyling – da lei stessa pubblicato sul «Bollettino d’Arte del Ministero dell’Educazione Nazionale» –  che rispondeva, per molti aspetti, agli orientamenti museografi ci espressi in quegli anni dall’Offi ce International des Musées (OIM e oggetto di approfondita rifl essione nell’ambito del dibattito europeo. L’intervento di Maria Accascina cambiò il volto del Museo Nazionale di Palermo – fi no a quel momento caratterizzato da sale e corridoi occupati «dalla più difforme congerie di oggetti» – anticipando indirizzi museografi ci che trovarono una concreta e tangibile applicazione durante il secondo dopoguerra nel più noto intervento di Carlo Scarpa all’interno di Palazzo Abatellis. Il contributo intende quindi analizzare l’allestimento di fi ne anni Venti del Museo Nazionale palermitano – di cui recentemente è stato sottolineato il carattere innovativo per quel momento – alla luce sia del ricco materiale documentario e fotografi co, in gran parte inedito, sia delle posizioni della critica del tempo e dei nuovi criteri di ordinamento dei musei che si andarono affermando nel periodo tra le due guerre mondiali. Museo Nazionale di Palermo distinguishes itself in the scope of Italian museums in the 1920’s as outlined by Francesco Pellati in Enquête internationale sur la réforme des galeries publiques. The young inspector Maria Accascina had just completed the reordering and installation of the medieval and modern art section. The art historian, a pupil of Adolfo Venturi, had

  11. Numerical and Experimental Characterization of a Composite Secondary Bonded Adhesive Lap Joint Using the Ultrasonics method

    Science.gov (United States)

    Kumar, M. R.; Ghosh, A.; Karuppannan, D.

    2018-05-01

    The construction of aircraft using advanced composites have become very popular during the past two decades, in which many innovative manufacturing processes, such as cocuring, cobonding, and secondary bonding processes, have been adopted. The secondary bonding process has become less popular than the other two ones because of nonavailability of process database and certification issues. In this article, an attempt is made to classify the quality of bonding using nondestructive ultrasonic inspection methods. Specimens were prepared and tested using the nondestructive ultrasonic Through Transmission (TT), Pulse Echo (PE), and air coupled guided wave techniques. It is concluded that the ultrasonic pulse echo technique is the best one for inspecting composite secondary bonded adhesive joints.

  12. 77 FR 27746 - Notice of Submission for OMB Review; Federal Student Aid; Lender Application Process (LAP)

    Science.gov (United States)

    2012-05-11

    ... Records Management Services, Office of Management, publishes this notice containing proposed information..., Information Collection Clearance Division, Privacy, Information and Records Management Services, Office of Management. [FR Doc. 2012-11378 Filed 5-10-12; 8:45 am] BILLING CODE 4000-01-P ...

  13. Physical Activity and Energy Expenditure during an After-School Running Club: Laps versus Game Play

    Science.gov (United States)

    Kahan, David; McKenzie, Thomas L.

    2018-01-01

    Background: After-school programs (ASPs) have the potential to contribute to student physical activity (PA), but there is limited empirical evidence to guide program development and implementation. Methods: We used pedometry to assess the overall effectiveness of an elementary school ASP running program relative to national and state PA…

  14. The concept of laparoscopy-assisted pancreatobiliary EUS (LAP-EUS).

    Science.gov (United States)

    Ramesh, Jayapal; Christein, John; Varadarajulu, Shyam

    2013-05-01

    While laparoscopy-assisted endoscopic retrograde cholangiopancreatography can be performed for the diagnosis and management of pancreaticobiliary diseases in patients with Roux-en-Y (RY) anatomy; the technical feasibility of performing laparoscopy-assisted endoscopic ultrasound (EUS) is unknown. In this report, we describe the technique for performing laparoscopy-assisted EUS in two patients with RY gastric bypass anatomy who presented with obstructive jaundice, abnormal liver function tests, and dilated biliary tree. While the examination was normal in one patient, EUS-guided fine needle aspiration of pancreatic head mass revealed adenocarcinoma in the other. Laparoscopic assisted EUS examination including FNA is feasible in Roux-en-Y surgical anatomy.

  15. The Landsat Phenology Study (LaPS): Preliminary CONUS Results for 2008

    Science.gov (United States)

    Henebry, Geoffrey M.; Roy, David P.; Ju, Junchang; Kovalskyy, Valeriy

    2010-05-01

    Most studies of land surface phenology (LSP) have used time series derived from moderate spatial resolution satellite sensor data (e.g., AVHRR, MODIS, VEGETATION) because these data are freely available and because they provide an acceptable trade-off between higher, near daily, temporal frequency of observation needed to reduce cloud contamination against lower (500m-5km) spatial resolution. The recent opening of the USGS Landsat archive to web-enabled access presents the opportunity to explore how well Landsat time series can portray LSPs at high spatial resolution. The NASA Web-enabled Landsat data (WELD) project (http://landsat.usgs.gov/WELD.php) has produced 30m composited mosaics for all the conterminous US (CONUS) from Landsat 7 ETM+ data. The composited mosaics are generated on monthly, seasonal, and annual basis and include spectral reflectance, normalized difference vegetation index (NDVI), and the acquisition date of each composited pixel. The WELD compositing approach is designed to select valid land surface observations with minimal cloud, snow, and atmospheric contamination. We extracted 30m pixel time series from the twelve monthly WELD composited mosaics for 2008 at 320 locations across the CONUS where we have ground phenological observations that are heterogeneous with respect to the types of plants observed, the phenophases recorded (predominantly spring green-up) and the ground sampling protocols used. The ground data came from several sources, including the cloned lilac/honeysuckle network, the Phenocam network, five LTER sites (H.J. Andrews, Harvard Forest, Jornada, Konza Prairie, and Sevilleta), and a private woodlot in Maine. Temporal profiles of the 30m WELD Landsat NDVI, the green NDVI (GNDVI), the normalized difference infrared index (NDII) derived from the composited reflectances, are compared to the ground observations. Results show that (i) inclusion of the Landsat acquisition date for each pixel improves the characterization of the LSP, (ii) the use of the NDII and GNDVI in conjunction with the NDVI improves identification of the onset both of canopy development and senescence, and (iii) the WELD compositing approach and the resulting mosaics provide a rich new data source for phenological investigations.

  16. Determination of Total Carbohydrates in Algal Biomass: Laboratory Analytical Procedure (LAP)

    Energy Technology Data Exchange (ETDEWEB)

    Van Wychen, Stefanie; Laurens, Lieve M. L.

    2016-01-13

    This procedure uses two-step sulfuric acid hydrolysis to hydrolyze the polymeric forms of carbohydrates in algal biomass into monomeric subunits. The monomers are then quantified by either HPLC or a suitable spectrophotometric method.

  17. Summative Mass Analysis of Algal Biomass - Integration of Analytical Procedures: Laboratory Analytical Procedure (LAP)

    Energy Technology Data Exchange (ETDEWEB)

    Laurens, Lieve M. L.

    2016-01-13

    This procedure guides the integration of laboratory analytical procedures to measure algal biomass constituents in an unambiguous manner and ultimately achieve mass balance closure for algal biomass samples. Many of these methods build on years of research in algal biomass analysis.

  18. Effect of tension lap splice on the behavior of high strength concrete (HSC beams

    Directory of Open Access Journals (Sweden)

    Ahmed El-Azab

    2014-12-01

    Full Text Available In the recent years, many research efforts have been carried out on the bond strength between normal strength concrete (NSC and reinforcing bars spliced in tension zones in beams. Many codes gave a minimum splice length for tension and compression reinforcement as a factor of the bar diameter depending on many parameters such as concrete strength, steel yield stress, shape of bar end, shape of bar surface and also bar location. Also, codes gave another restriction about the percentage of total reinforcement to be spliced at the same time. Comparatively limited attention has been directed toward the bond between high strength concrete (HSC and reinforcing bars spliced in tension zones in beams. HSC has high modulus of elasticity, high density and long-term durability. This research presents an experimental study on the bond between high strength concrete (HSC and reinforcing bars spliced in tension zones in beams. It reports the influence of several parameters on bond in splices. The parameters covered are casting position, splice length as a factor of bar diameter, bar diameter and reinforcement ratio. The research involved tests on sixteen simply-supported beams of 1800 mm span, 200 mm width and 400 mm thickness made of HSC. In each beam, the total tensile steel bars were spliced in the constant moment zone. Crack pattern, crack propagation, cracking load, failure load and mi span deflection were recorded and analyzed to study the mentioned parameters effect.

  19. Single Side Electrolytic In-Process Dressing (ELID) Grinding with Lapping Kinematics of Silicon Carbide

    Science.gov (United States)

    Khoshaim, Ahmed Bakr

    The demand for Silicon Carbide ceramics (SiC) has increased significantly in the last decade due to its reliable physical and chemical properties. The silicon carbide is widely used for aerospace segments in addition to many uses in the industry. Sometimes, a single side grinding is preferable than conventional grinding, for it has the ability to produce flat ceramics. However, the manufacturing cost is still high because of the high tool wear and long machining time. Part of the solution is to use electrolytic in process dressing (ELID) to reduce the processing time. The study on ELID single side grinding of ceramics has never been attempted before. The study involves four variables with three levels each. One of the variables, which is the eccentricity, is being investigated for the first time on ceramics. A full factorial design, for both the surface roughness and material removal rate, guides to calculate mathematical models that can predict future results. Three grinding wheel mesh sizes are used. An investigation of the influence of different grain size on the results can then be evaluated. The kinematics of the process was studied based on eccentricity in order to optimize the pattern of the diamond grains. The experiment is performed with the assist of the proposed specialized ELID fluid, TRIM C270E.

  20. Lap Shear and Impact Testing of Ochre and Beeswax in Experimental Middle Stone Age Compound Adhesives

    NARCIS (Netherlands)

    Kozowyk, P.R.B.; Langejans, G.; Poulis, J.A.

    2016-01-01

    The production of compound adhesives using disparate ingredients is seen as some of the best evidence of advanced cognition outside of the use of symbolism. Previous field and laboratory testing of adhesives has shown the complexities involved in creating an effective Middle Stone Age glue using