WorldWideScience

Sample records for laboratory testing programs

  1. Mobile Energy Laboratory energy-efficiency testing programs

    International Nuclear Information System (INIS)

    Parker, G.B.; Currie, J.W.

    1992-03-01

    This report summarizes energy-efficiency testing activities applying the Mobile Energy Laboratory (MEL) testing capabilities during the third and fourth quarters of fiscal year (FY) 1991. The MELs, developed by the US Department of Energy (DOE) Federal Energy Management Program (FEMP), are administered by Pacific Northwest Laboratory (PNL) and the Naval Energy and Environmental Support Activity (NEESA) for energy testing and energy conservation program support functions at federal facilities. The using agencies principally fund MEL applications, while DOE/FEMP funds program administration and capability enhancement activities. This report fulfills the requirements established in Section 8 of the MEL Use Plan (PNL-6861) for semi-annual reporting on energy-efficiency testing activities using the MEL capabilities. The MEL Use Committee, formally established in 1989, developed the MEL Use Plan and meets semi-annually to establish priorities for energy-efficient testing applications using the MEL capabilities. The MEL Use Committee is composed of one representative each of the US Department of Energy, US Army, US Air Force, US Navy, and other federal agencies

  2. Mobile Energy Laboratory energy-efficiency testing programs

    Energy Technology Data Exchange (ETDEWEB)

    Parker, G B; Currie, J W

    1992-03-01

    This report summarizes energy-efficiency testing activities applying the Mobile Energy Laboratory (MEL) testing capabilities during the third and fourth quarters of fiscal year (FY) 1991. The MELs, developed by the US Department of Energy (DOE) Federal Energy Management Program (FEMP), are administered by Pacific Northwest Laboratory (PNL) and the Naval Energy and Environmental Support Activity (NEESA) for energy testing and energy conservation program support functions at federal facilities. The using agencies principally fund MEL applications, while DOE/FEMP funds program administration and capability enhancement activities. This report fulfills the requirements established in Section 8 of the MEL Use Plan (PNL-6861) for semi-annual reporting on energy-efficiency testing activities using the MEL capabilities. The MEL Use Committee, formally established in 1989, developed the MEL Use Plan and meets semi-annually to establish priorities for energy-efficient testing applications using the MEL capabilities. The MEL Use Committee is composed of one representative each of the US Department of Energy, US Army, US Air Force, US Navy, and other federal agencies.

  3. 78 FR 7460 - Stakeholder Meeting on the Nationally Recognized Testing Laboratory Program

    Science.gov (United States)

    2013-02-01

    ...] Stakeholder Meeting on the Nationally Recognized Testing Laboratory Program AGENCY: Occupational Safety and Health Administration (OSHA), Labor. ACTION: Notice of stakeholder meeting. SUMMARY: OSHA invites interested parties to attend an informal stakeholder meeting concerning Nationally Recognized Testing...

  4. The Livermore Free-Electron Laser Program Magnet Test Laboratory

    International Nuclear Information System (INIS)

    Burns, M.J.; Kulke, B.; Deis, G.A.; Frye, R.W.; Kallman, J.S.; Ollis, C.W.; Tyler, G.C.; Van Maren, R.D.; Weiss, W.C.

    1987-01-01

    The Lawrence Livermore National Laboratory (LLNL) Free-Electron Laser Program Magnet Test Laboratory supports the ongoing development of the Induction Linac Free Electron Laser (IFEL) and uses magnetic field measurement systems that are useful in the testing of long periodic magnetic structures, electron-beam transport magnets, and spectrometer magnets. The major systems described include two computer-controlled, three-axis Hall probe-and-search coil transports with computer-controlled data acquisition; a unique, automated-search coil system used to detect very small inaccuracies in wiggler fields; a nuclear magnetic resonance (NMR)-based Hall probe-calibration facility; and a high-current DC ion source using heavy ions of variable momentum to model the transport of high-energy electrons. Additionally, a high-precision electron-beam-position monitor for use within long wigglers that has a positional resolution of less than 100 μm is under development in the laboratory and will be discussed briefly. Data transfer to LLNL's central computing facility and on-line graphics enable us to analyze large data sets quickly. 3 refs

  5. Lawrence Livermore Laboratory's beryllium control program for high-explosive test firing bunkers and tables

    International Nuclear Information System (INIS)

    Johnson, J.S.

    1978-01-01

    This detailed report on Lawrence Livermore Laboratory's control program to minimize beryllium levels in Laboratory workplaces includes an outline of beryllium surface, soil, and air levels and an 11-y summary of sampling results from two high-use, high-explosive test firing bunkers. These sampling data and other studies demonstrate that the beryllium control program is funcioning effectively

  6. Relay testing at Brookhaven National Laboratory

    International Nuclear Information System (INIS)

    Bandyopadhyay, K.; Hofmayer, C.

    1989-01-01

    Brookhaven National Laboratory (BNL) is conducting a seismic test program on relays. The purpose of the test program is to investigate the influence of various designs, electrical and vibration parameters on the seismic capacity levels. The first series of testing has been completed and performed at Wyle Laboratories. The major part of the test program consisted of single axis, single frequency sine dwell tests. Random multiaxis, multifrequency tests were also performed. Highlights of the test results as well as a description of the testing methods are presented in this paper. 10 figs

  7. CRCPD`S laboratory accrediation program

    Energy Technology Data Exchange (ETDEWEB)

    Dukes, P.M. [South Carolina Department of Health and Environmental Control, Columbia, SC (United States)

    1993-12-31

    The Conference of Radiation Control Program Directors, or CRCPD, first became involved in a calibration laboratory accreditation program about 17 years ago. Since that time, the CRCPD has formed a Committee on Ionizing Measurements which writes criteria for the accreditation of laboratories, and performs the accreditation review process. To become accredited, a laboratory must agree to an administrative review, and an onsite review, and participate in measurement quality assurance (MQA) testing with the National Institute of Standards and Technology (NIST). The CRCPD currently has four accredited laboratories. All the laboratories are working with the Conference in promoting the improvement of MQA in radiation control programs.

  8. Summary of the Mol electrolysis cell test program in the CRL tritium laboratory

    International Nuclear Information System (INIS)

    Miller, J.M.; Keyes, R.J.

    1996-01-01

    The development of electrolysis technology for highly tritiated water at the Studiecentrum voor Kernenergie/Centre d'Etude de l'Energie Nucleaire (SCK/CEN), Mol, Belgium, focused on A Low Inventory Capillary Electrolyser (ALICE). The key characteristic of ALICE is its low liquid inventory, a key feature for the radio-toxicity of tritiated water. A program to test this electrolytic cell design with highly tritiated water in the Chalk River Tritium Laboratory was initiated in 1988 and extended through to early 1995. The activities conducted at CRL and associated with the experimental program-design, installation, licensing and commissioning activities- are described in this report along with the results of the test program conducted on the experimental system with non-tritiated heavy water. The installation in the CRL Tritium Laboratory consisted of three main sections: the electrolysis section, the tritium storage and supply section, and the recombination section. 16 figs., 2 tabs., 10 refs

  9. Transportable Heavy Duty Emissions Testing Laboratory and Research Program

    Energy Technology Data Exchange (ETDEWEB)

    David Lyons

    2008-03-31

    The objective of this program was to quantify the emissions from heavy-duty vehicles operating on alternative fuels or advanced fuel blends, often with novel engine technology or aftertreatment. In the first year of the program West Virginia University (WVU) researchers determined that a transportable chassis dynamometer emissions measurement approach was required so that fleets of trucks and buses did not need to be ferried across the nation to a fixed facility. A Transportable Heavy-Duty Vehicle Emissions Testing Laboratory (Translab) was designed, constructed and verified. This laboratory consisted of a chassis dynamometer semi-trailer and an analytic trailer housing a full scale exhaust dilution tunnel and sampling system which mimicked closely the system described in the Code of Federal Regulations for engine certification. The Translab was first used to quantify emissions from natural gas and methanol fueled transit buses, and a second Translab unit was constructed to satisfy research demand. Subsequent emissions measurement was performed on trucks and buses using ethanol, Fischer-Tropsch fuel, and biodiesel. A medium-duty chassis dynamometer was also designed and constructed to facilitate research on delivery vehicles in the 10,000 to 20,000lb range. The Translab participated in major programs to evaluate low-sulfur diesel in conjunction with passively regenerating exhaust particulate filtration technology, and substantial reductions in particulate matter were recorded. The researchers also participated in programs to evaluate emissions from advanced natural gas engines with closed loop feedback control. These natural gas engines showed substantially reduced levels of oxides of nitrogen. For all of the trucks and buses characterized, the levels of carbon monoxide, oxides of nitrogen, hydrocarbons, carbon dioxide and particulate matter were quantified, and in many cases non-regulated species such as aldehydes were also sampled. Particle size was also

  10. Relay test program

    International Nuclear Information System (INIS)

    Bandyopadhyay, K.K.; Kunkel, C.; Shteyngart, S.

    1994-02-01

    This report presents the results of a relay test program conducted by Brookhaven National Laboratory (BNL) under the sponsorship of the US Nuclear Regulatory Commission (NRC). The program is a continuation of an earlier test program the results of which were published in NUREG/CR-4867. The current program was carried out in two phases: electrical testing and vibration testing. The objective was primarily to focus on the electrical discontinuity or continuity of relays and circuit breaker tripping mechanisms subjected to electrical pulses and vibration loads. The electrical testing was conducted by KEMA-Powertest Company and the vibration testing was performed at Wyle Laboratories, Huntsville, Alabama. This report discusses the test procedures, presents the test data, includes an analysis of the data and provides recommendations regarding reliable relay testing

  11. Mobile Energy Laboratory energy-efficiency testing programs. Semiannual report, April 1, 1991--September 30, 1991

    Energy Technology Data Exchange (ETDEWEB)

    Parker, G. B.; Currie, J. W.

    1992-03-01

    This report summarizes energy-efficiency testing activities applying the Mobile Energy Laboratory (MEL) testing capabilities during the third and fourth quarters of fiscal year (FY) 1991. The MELs, developed by the US Department of Energy (DOE) Federal Energy Management Program (FEMP), are administered by Pacific Northwest Laboratory (PNL) and the Naval Energy and Environmental Support Activity (NEESA) for energy testing and energy conservation program support functions at federal facilities. The using agencies principally fund MEL applications, while DOE/FEMP funds program administration and capability enhancement activities. This report fulfills the requirements established in Section 8 of the MEL Use Plan (PNL-6861) for semi-annual reporting on energy-efficiency testing activities using the MEL capabilities. The MEL Use Committee, formally established in 1989, developed the MEL Use Plan and meets semi-annually to establish priorities for energy-efficient testing applications using the MEL capabilities. The MEL Use Committee is composed of one representative each of the US Department of Energy, US Army, US Air Force, US Navy, and other federal agencies.

  12. Secondary calibration laboratory for ionizing radiation laboratory accreitation program National Institute of Standards and Technology National Voluntary Laboratory Accreditation Program

    Energy Technology Data Exchange (ETDEWEB)

    Martin, P.R.

    1993-12-31

    This paper presents an overview of the procedures and requirements for accreditation under the Secondary Calibration Laboratory for Ionizing Radiation Program (SCLIR LAP). The requirements for a quality system, proficiency testing and the onsite assessment are discussed. The purpose of the accreditation program is to establish a network of secondary calibration laboratories that can provide calibrations traceable to the primary national standards.

  13. Secondary calibration laboratory for ionizing radiation laboratory accreitation program National Institute of Standards and Technology National Voluntary Laboratory Accreditation Program

    International Nuclear Information System (INIS)

    Martin, P.R.

    1993-01-01

    This paper presents an overview of the procedures and requirements for accreditation under the Secondary Calibration Laboratory for Ionizing Radiation Program (SCLIR LAP). The requirements for a quality system, proficiency testing and the onsite assessment are discussed. The purpose of the accreditation program is to establish a network of secondary calibration laboratories that can provide calibrations traceable to the primary national standards

  14. Lawrence Livermore Laboratory's beryllium control program for high-explosive test firing bunkers and tables

    International Nuclear Information System (INIS)

    Johnson, J.S.

    1980-01-01

    This report on the control program to minimize beryllium levels in Laboratory workplaces includes an outline of beryllium surface, soil, and air levels and an 11-y summary of sampling results from two high-use, high-explosive test firing bunkers. These sampling data and other studies demonstrate that the beryllium control program is functioning effectively

  15. The DOE Laboratory Accreditation Program 8 years later

    International Nuclear Information System (INIS)

    Cummings, R.; Kershisnik, R.; Taylor, T.; Grothaus, G.; Loesch, R.M.

    1994-01-01

    The DOE Laboratory Accreditation Program was implemented in 1986. Currently, the program is conducting its seventeenth performance testing session for whole body personnel dosimeters. All but two DOE laboratories have gained accreditation for their whole body personnel dosimetry systems. Several test situations which were anticipated in the early stages of DOELAP have not materialized. In addition, the testing standard for whole body personnel dosimetry systems is under review and revision. In the near future, the accreditation programs for extremity dosimetry and bioassay will be implemented. This presentation summarizes the status and anticipated direction of the DOE whole body and extremity dosimetry and bioassay laboratory accreditation program

  16. Safety in the Chemical Laboratory: Safety in the Chemistry Laboratories: A Specific Program.

    Science.gov (United States)

    Corkern, Walter H.; Munchausen, Linda L.

    1983-01-01

    Describes a safety program adopted by Southeastern Louisiana University. Students are given detailed instructions on laboratory safety during the first laboratory period and a test which must be completely correct before they are allowed to return to the laboratory. Test questions, list of safety rules, and a laboratory accident report form are…

  17. The U.S. Department of Energy Laboratory Accreditation Program for testing the performance of extremity dosimetry systems: a summary of the program status

    International Nuclear Information System (INIS)

    Cummings, F.M.; Carlson, R.D.; Gesell, T.F.; Loesch, R.M.

    1992-01-01

    In 1986, The U.S. Department of Energy (DOE) implemented a program to test the performance of its personnel whole-body dosimetry systems. This program was the DOE Laboratory Accreditation Program (DOELAP). The program parallels the performance testing program specified in the American National Standard for Dosimetry - Personnel Dosimetry Performance -Criteria for Testing (ANSI N13.11-1983), but also addresses the additional dosimetry needs of DOE facilities. As an extension of the whole-body performance testing program, the DOE is now developing a program to test the performance of personnel extremity dosimetry systems. The draft DOE standard for testing extremity dosimetry systems is much less complex than the whole-body dosimetry standard and reflects the limitations imposed on extremity dosimetry by dosimeter design and irradiation geometry. A pilot performance test session has been conducted to evaluate the proposed performance-testing standard. (author)

  18. Sandia Laboratories technical capabilities: testing

    International Nuclear Information System (INIS)

    Lundergan, C.D.

    1975-12-01

    The testing capabilities at Sandia Laboratories are characterized. Selected applications of these capabilities are presented to illustrate the extent to which they can be applied in research and development programs

  19. Laboratory creep and mechanical tests on salt data report (1975-1996): Waste Isolation Pilot Plant (WIPP) thermal/structural interactions program

    Energy Technology Data Exchange (ETDEWEB)

    Mellegard, K.D. [RE/SPEC Inc., Rapid City, SD (United States); Munson, D.E. [Sandia National Labs., Albuquerque, NM (United States)

    1997-02-01

    The Waste Isolation Pilot Plant (WIPP), a facility located in a bedded salt formation in Carlsbad, New Mexico, is being used by the U.S. Department of Energy to demonstrate the technology for safe handling and disposal of transuranic wastes produced by defense activities in the United States. In support of that demonstration, mechanical tests on salt were conducted in the laboratory to characterize material behavior at the stresses and temperatures expected for a nuclear waste repository. Many of those laboratory test programs have been carried out in the RE/SPEC Inc. rock mechanics laboratory in Rapid City, South Dakota; the first program being authorized in 1975 followed by additional testing programs that continue to the present. All of the WIPP laboratory data generated on salt at RE/SPEC Inc. over the last 20 years is presented in this data report. A variety of test procedures were used in performance of the work including quasi-static triaxial compression tests, constant stress (creep) tests, damage recovery tests, and multiaxial creep tests. The detailed data is presented in individual plots for each specimen tested. Typically, the controlled test conditions applied to each specimen are presented in a plot followed by additional plots of the measured specimen response. Extensive tables are included to summarize the tests that were performed. Both the tables and the plots contain cross-references to the technical reports where the data were originally reported. Also included are general descriptions of laboratory facilities, equipment, and procedures used to perform the work.

  20. In situ vitrification laboratory-scale test work plan

    International Nuclear Information System (INIS)

    Nagata, P.K.; Smith, N.L.

    1991-05-01

    The Buried Waste Program was established in October 1987 to accelerate the studies needed to develop a long-term management plan for the buried mixed waste at the Radioactive Waste Management Complex at Idaho Engineering Laboratory. The In Situ Vitrification Project is being conducted in a Comprehensive Environmental Response, Compensation, and Liability Act feasibility study format to identify methods for the long-term management of mixed buried waste. To support the overall feasibility study, the situ vitrification treatability investigations are proceeding along the three parallel paths: laboratory-scale tests, intermediate field tests, and field tests. Laboratory-scale tests are being performed to provide data to mathematical modeling efforts, which, in turn, will support design of the field tests and to the health and safety risk assessment. This laboratory-scale test work plan provides overall testing program direction to meet the current goals and objectives of the in situ vitrification treatability investigation. 12 refs., 1 fig., 7 tabs

  1. 75 FR 30041 - Medicare Program; Public Meeting in Calendar Year 2010 for New Clinical Laboratory Tests Payment...

    Science.gov (United States)

    2010-05-28

    ... specified list of new Clinical Procedural Terminology (CPT) codes for clinical laboratory tests in calendar... are codified at 42 CFR part 414, subpart G. A newly created Current Procedural Terminology (CPT) code..., Medicare--Hospital Insurance; and Program No. 93.774, Medicare-- Supplementary Medical Insurance Program...

  2. Laboratory development and testing of spacecraft diagnostics

    Science.gov (United States)

    Amatucci, William; Tejero, Erik; Blackwell, Dave; Walker, Dave; Gatling, George; Enloe, Lon; Gillman, Eric

    2017-10-01

    The Naval Research Laboratory's Space Chamber experiment is a large-scale laboratory device dedicated to the creation of large-volume plasmas with parameters scaled to realistic space plasmas. Such devices make valuable contributions to the investigation of space plasma phenomena under controlled, reproducible conditions, allowing for the validation of theoretical models being applied to space data. However, in addition to investigations such as plasma wave and instability studies, such devices can also make valuable contributions to the development and testing of space plasma diagnostics. One example is the plasma impedance probe developed at NRL. Originally developed as a laboratory diagnostic, the sensor has now been flown on a sounding rocket, is included on a CubeSat experiment, and will be included on the DoD Space Test Program's STP-H6 experiment on the International Space Station. In this talk, we will describe how the laboratory simulation of space plasmas made this development path possible. Work sponsored by the US Naval Research Laboratory Base Program.

  3. Laboratory directed research and development program, FY 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-02-01

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab) Laboratory Directed Research and Development Program FY 1996 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the projects supported and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development (LDRD) program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The Berkeley Lab LDRD program is a critical tool for directing the Laboratory`s forefront scientific research capabilities toward vital, excellent, and emerging scientific challenges. The program provides the resources for Berkeley Lab scientists to make rapid and significant contributions to critical national science and technology problems. The LDRD program also advances the Laboratory`s core competencies, foundations, and scientific capability, and permits exploration of exciting new opportunities. Areas eligible for support include: (1) Work in forefront areas of science and technology that enrich Laboratory research and development capability; (2) Advanced study of new hypotheses, new experiments, and innovative approaches to develop new concepts or knowledge; (3) Experiments directed toward proof of principle for initial hypothesis testing or verification; and (4) Conception and preliminary technical analysis to explore possible instrumentation, experimental facilities, or new devices.

  4. Test Program Set (TPS) Lab

    Data.gov (United States)

    Federal Laboratory Consortium — The ARDEC TPS Laboratory provides an organic Test Program Set (TPS) development, maintenance, and life cycle management capability for DoD LCMC materiel developers....

  5. Evaluation of the Virtual Physiology of Exercise Laboratory Program

    Science.gov (United States)

    Dobson, John L.

    2009-01-01

    The Virtual Physiology of Exercise Laboratory (VPEL) program was created to simulate the test design, data collection, and analysis phases of selected exercise physiology laboratories. The VPEL program consists of four modules: (1) cardiovascular, (2) maximal O[subscript 2] consumption [Vo[subscript 2max], (3) lactate and ventilatory thresholds,…

  6. Clinical pharmacology quality assurance program: models for longitudinal analysis of antiretroviral proficiency testing for international laboratories.

    Science.gov (United States)

    DiFrancesco, Robin; Rosenkranz, Susan L; Taylor, Charlene R; Pande, Poonam G; Siminski, Suzanne M; Jenny, Richard W; Morse, Gene D

    2013-10-01

    Among National Institutes of Health HIV Research Networks conducting multicenter trials, samples from protocols that span several years are analyzed at multiple clinical pharmacology laboratories (CPLs) for multiple antiretrovirals. Drug assay data are, in turn, entered into study-specific data sets that are used for pharmacokinetic analyses, merged to conduct cross-protocol pharmacokinetic analysis, and integrated with pharmacogenomics research to investigate pharmacokinetic-pharmacogenetic associations. The CPLs participate in a semiannual proficiency testing (PT) program implemented by the Clinical Pharmacology Quality Assurance program. Using results from multiple PT rounds, longitudinal analyses of recovery are reflective of accuracy and precision within/across laboratories. The objectives of this longitudinal analysis of PT across multiple CPLs were to develop and test statistical models that longitudinally: (1) assess the precision and accuracy of concentrations reported by individual CPLs and (2) determine factors associated with round-specific and long-term assay accuracy, precision, and bias using a new regression model. A measure of absolute recovery is explored as a simultaneous measure of accuracy and precision. Overall, the analysis outcomes assured 97% accuracy (±20% of the final target concentration of all (21) drug concentration results reported for clinical trial samples by multiple CPLs). Using the Clinical Laboratory Improvement Act acceptance of meeting criteria for ≥2/3 consecutive rounds, all 10 laboratories that participated in 3 or more rounds per analyte maintained Clinical Laboratory Improvement Act proficiency. Significant associations were present between magnitude of error and CPL (Kruskal-Wallis P Kruskal-Wallis P < 0.001).

  7. Recommended procedures for performance testing of radiobioassay laboratories: Volume 3, In vivo test phantoms

    International Nuclear Information System (INIS)

    MacLellan, J.A.; Traub, R.J.

    1988-11-01

    Draft American National Standards Institute (ANSI) Standard N13.30 (Performance Criteria for Radiobioassay) was developed for the US Department of Energy and the US Nuclear Regulatory Commission to help ensure that bioassay laboratories provide accurate and consistent results. The draft standard describes the procedures necessary to establish a bioassay performance-testing laboratory and program. The bioassay performance-testing laboratory will conduct tests to evaluate the performance of service laboratories. Pacific Northwest Laboratory helped develop testing procedures as part of an effort to evaluate the draft ANSI N13.30 performance criteria by testing the existing measurement capabilities of various bioassay laboratories. This report recommends guidelines for the preparation, handling, storage, distribution, shipping, and documentation of test phantoms used for calibration of measurement systems for direct bioassay. The data base and recommended records system for documenting radiobioassay performance at the service laboratories are also presented

  8. Laboratory directed research and development program, FY 1996

    International Nuclear Information System (INIS)

    1997-02-01

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab) Laboratory Directed Research and Development Program FY 1996 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the projects supported and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development (LDRD) program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The Berkeley Lab LDRD program is a critical tool for directing the Laboratory's forefront scientific research capabilities toward vital, excellent, and emerging scientific challenges. The program provides the resources for Berkeley Lab scientists to make rapid and significant contributions to critical national science and technology problems. The LDRD program also advances the Laboratory's core competencies, foundations, and scientific capability, and permits exploration of exciting new opportunities. Areas eligible for support include: (1) Work in forefront areas of science and technology that enrich Laboratory research and development capability; (2) Advanced study of new hypotheses, new experiments, and innovative approaches to develop new concepts or knowledge; (3) Experiments directed toward proof of principle for initial hypothesis testing or verification; and (4) Conception and preliminary technical analysis to explore possible instrumentation, experimental facilities, or new devices

  9. Testing activities at the National Battery Test Laboratory

    Science.gov (United States)

    Hornstra, F.; Deluca, W. H.; Mulcahey, T. P.

    The National Battery Test Laboratory (NBTL) is an Argonne National Laboratory facility for testing, evaluating, and studying advanced electric storage batteries. The facility tests batteries developed under Department of Energy programs and from private industry. These include batteries intended for future electric vehicle (EV) propulsion, electric utility load leveling (LL), and solar energy storage. Since becoming operational, the NBTL has evaluated well over 1400 cells (generally in the form of three- to six-cell modules, but up to 140-cell batteries) of various technologies. Performance characterization assessments are conducted under a series of charge/discharge cycles with constant current, constant power, peak power, and computer simulated dynamic load profile conditions. Flexible charging algorithms are provided to accommodate the specific needs of each battery under test. Special studies are conducted to explore and optimize charge procedures, to investigate the impact of unique load demands on battery performance, and to analyze the thermal management requirements of battery systems.

  10. Strategy for future laboratory rock mechanics programs

    International Nuclear Information System (INIS)

    Butcher, B.M.; Jones, A.K.

    1985-01-01

    A strategy for future experimental rock mechanics laboratory programs at Sandia National Laboratories is described. This strategy is motivated by the need for long range planning of rock mechanics programs addressing the stability of complex underground structures, changes in in situ stress states during resource recovery and underground explosion technology. It is based on: (1) recent advances in underground structure stability analysis which make three-dimensional calculations feasible, and (2) new developments in load path control of laboratory stress-strain tests which permit duplication of stress and strain histories in critical parts of a structure, as determined by numerical analysis. The major constraint in the strategy is the assumption that there are no in situ joint features or sample size effects which might prevent simulation of in situ response in the laboratory. 3 refs., 5 figs

  11. Prototype steam generator test at SCTI/ETEC. Acoustic program test plan

    International Nuclear Information System (INIS)

    Greene, D.A.; Thiele, A.; Claytor, T.N.

    1981-10-01

    This document is an integrated test plan covering programs at General Electric (ARSD), Rockwell International (RI) and Argonne National Laboratory (CT). It provides an overview of the acoustic leak detection test program which will be completed in conjunction with the prototype LMFBR steam generator at the Energy Technology Engineering Laboratory. The steam generator is installed in the Sodium Components Test Installation (SCTI). Two acoustic detection systems will be used during the test program, a low frequency system developed by GE-ARSD (GAAD system) and a high frequency system developed by RI-AI (HALD system). These systems will be used to acquire data on background noise during the thermal-hydraulic test program. Injection devices were installed during fabrication of the prototype steam generator to provide localized noise sources in the active region of the tube bundle. These injectors will be operated during the steam generator test program, and it will be shown that they are detected by the acoustic systems

  12. NVLAP calibration laboratory program

    Energy Technology Data Exchange (ETDEWEB)

    Cigler, J.L.

    1993-12-31

    This paper presents an overview of the progress up to April 1993 in the development of the Calibration Laboratories Accreditation Program within the framework of the National Voluntary Laboratory Accreditation Program (NVLAP) at the National Institute of Standards and Technology (NIST).

  13. NVLAP calibration laboratory program

    International Nuclear Information System (INIS)

    Cigler, J.L.

    1993-01-01

    This paper presents an overview of the progress up to April 1993 in the development of the Calibration Laboratories Accreditation Program within the framework of the National Voluntary Laboratory Accreditation Program (NVLAP) at the National Institute of Standards and Technology (NIST)

  14. Recommended procedures for performance testing of radiobioassay laboratories: Volume 1, Quality assurance

    International Nuclear Information System (INIS)

    Fenrick, H.W.; MacLellan, J.A.

    1988-11-01

    Draft American National Standards Institute (ANSI) Standard N13.30 (Performance Criteria for Radiobioassay) was developed in response to a concern expressed by the US Department of Energy and US Nuclear Regulatory Commission to help ensure that bioassay laboratories provide accurate and consistent results. The draft standard specifies the criteria for defining the procedures necessary to establish a bioassay performance-testing laboratory and program. The testing laboratory will conduct tests to evaluate the performance of service laboratories. Pacific Northwest Laboratory helped define responsibilities and develop procedures as part of an effort to evaluate the draft ANSI N13.30 performance criteria for quality assurance at bioassay laboratories. This report recommends elements of quality assurance and quality control responsibilities for the bioassay performance-testing laboratory program, including the qualification and performance of personnel and the calibration, certification, and performance of equipment. The data base and recommended records system for documenting radiobioassay performance at the service laboratories are also presented. 15 refs

  15. The Tanzania experience: clinical laboratory testing harmonization and equipment standardization at different levels of a tiered health laboratory system.

    Science.gov (United States)

    Massambu, Charles; Mwangi, Christina

    2009-06-01

    The rapid scale-up of the care and treatment programs in Tanzania during the preceding 4 years has greatly increased the demand for quality laboratory services for diagnosis of HIV and monitoring patients during antiretroviral therapy. Laboratory services were not in a position to cope with this demand owing to poor infrastructure, lack of human resources, erratic and/or lack of reagent supply and commodities, and slow manual technologies. With the limited human resources in the laboratory and the need for scaling up the care and treatment program, it became necessary to install automated equipment and train personnel for the increased volume of testing and new tests across all laboratory levels. With the numerous partners procuring equipment, the possibility of a multitude of equipment platforms with attendant challenges for procurement of reagents, maintenance of equipment, and quality assurance arose. Tanzania, therefore, had to harmonize laboratory tests and standardize laboratory equipment at different levels of the laboratory network. The process of harmonization of tests and standardization of equipment included assessment of laboratories, review of guidelines, development of a national laboratory operational plan, and stakeholder advocacy. This document outlines this process.

  16. Flow Induced Vibration Program at Argonne National Laboratory

    Science.gov (United States)

    1984-01-01

    The Argonne National Laboratory's Flow Induced Vibration Program, currently residing in the Laboratory's Components Technology Division is discussed. Throughout its existence, the overall objective of the program was to develop and apply new and/or improved methods of analysis and testing for the design evaluation of nuclear reactor plant components and heat exchange equipment from the standpoint of flow induced vibration. Historically, the majority of the program activities were funded by the US Atomic Energy Commission, the Energy Research and Development Administration, and the Department of Energy. Current DOE funding is from the Breeder Mechanical Component Development Division, Office of Breeder Technology Projects; Energy Conversion and Utilization Technology Program, Office of Energy Systems Research; and Division of Engineering, Mathematical and Geosciences, office of Basic Energy Sciences. Testing of Clinch River Breeder Reactor upper plenum components was funded by the Clinch River Breeder Reactor Plant Project Office. Work was also performed under contract with Foster Wheeler, General Electric, Duke Power Company, US Nuclear Regulatory Commission, and Westinghouse.

  17. Manipulator comparative testing program

    International Nuclear Information System (INIS)

    Draper, J.V.; Handel, S.J.; Sundstrom, E.; Herndon, J.N.; Fujita, Y.; Maeda, M.

    1986-01-01

    The Manipulator Comparative Testing Program examined differences among manipulator systems from the United States and Japan. The manipulator systems included the Meidensha BILARM 83A, the Model M-2 of Central Research Laboratories Division of Sargent Industries (CRL), and the GCA Corporation PaR Systems Model 6000. The site of testing was the Remote Operations Maintenance Demonstration (ROMD) facility, operated by the Fuel Recycle Division in the Consolidated Fuel Reprocessing Program at the Oak Ridge National Laboratory (ORNL). In all stages of testing, operators using the CRL Model M-2 manipulator had consistently lower times to completion and error rates than they did using other machines. Performance was second best with the Meidensha BILARM 83A in master-slave mode. Performance with the BILARM in switchbox mode and the PaR 6000 manipulator was approximately equivalent in terms of criteria recorded in testing. These data show no impact of force reflection on task performance

  18. Flow Induced Vibration Program at Argonne National Laboratory

    International Nuclear Information System (INIS)

    1984-01-01

    Argonne National Laboratory has had a Flow Induced Vibration Program since 1967; the Program currently resides in the Laboratory's Components Technology Division. Throughout its existence, the overall objective of the program has been to develop and apply new and/or improved methods of analysis and testing for the design evaluation of nuclear reactor plant components and heat exchange equipment from the standpoint of flow induced vibration. Historically, the majority of the program activities have been funded by the US Atomic Energy Commission (AEC), Energy Research and Development Administration (ERDA), and Department of Energy (DOE). Current DOE funding is from the Breeder Mechanical Component Development Division, Office of Breeder Technology Projects; Energy Conversion and Utilization Technology (ECUT) Program, Office of Energy Systems Research; and Division of Engineering, Mathematical and Geosciences, Office of Basic Energy Sciences. Testing of Clinch River Breeder Reactor upper plenum components has been funded by the Clinch River Breeder Reactor Plant (CRBRP) Project Office. Work has also been performed under contract with Foster Wheeler, General Electric, Duke Power Company, US Nuclear Regulatory Commission, and Westinghouse

  19. Evaluation of Mycology Laboratory Proficiency Testing

    Science.gov (United States)

    Reilly, Andrew A.; Salkin, Ira F.; McGinnis, Michael R.; Gromadzki, Sally; Pasarell, Lester; Kemna, Maggi; Higgins, Nancy; Salfinger, Max

    1999-01-01

    Changes over the last decade in overt proficiency testing (OPT) regulations have been ostensibly directed at improving laboratory performance on patient samples. However, the overt (unblinded) format of the tests and regulatory penalties associated with incorrect values allow and encourage laboratorians to take extra precautions with OPT analytes. As a result OPT may measure optimal laboratory performance instead of the intended target of typical performance attained during routine patient testing. This study addresses this issue by evaluating medical mycology OPT and comparing its fungal specimen identification error rates to those obtained in a covert (blinded) proficiency testing (CPT) program. Identifications from 188 laboratories participating in the New York State mycology OPT from 1982 to 1994 were compared with the identifications of the same fungi recovered from patient specimens in 1989 and 1994 as part of the routine procedures of 88 of these laboratories. The consistency in the identification of OPT specimens was sufficient to make accurate predictions of OPT error rates. However, while the error rates in OPT and CPT were similar for Candida albicans, significantly higher error rates were found in CPT for Candida tropicalis, Candida glabrata, and other common pathogenic fungi. These differences may, in part, be due to OPT’s use of ideal organism representatives cultured under optimum growth conditions. This difference, as well as the organism-dependent error rate differences, reflects the limitations of OPT as a means of assessing the quality of routine laboratory performance in medical mycology. PMID:10364601

  20. US Department of Energy Laboratory Accredition Program (DOELAP) for personnel dosimetry systems

    Energy Technology Data Exchange (ETDEWEB)

    Cummings, F.M.; Carlson, R.D.; Loesch, R.M.

    1993-12-31

    Accreditation of personnel dosimetry systems is required for laboratories that conduct personnel dosimetry for the U.S. Department of Energy (DOE). Accreditation is a two-step process which requires the participant to pass a proficiency test and an onsite assessment. The DOE Laboratory Accreditation Program (DOELAP) is a measurement quality assurance program for DOE laboratories. Currently, the DOELAP addresses only dosimetry systems used to assess the whole body dose to personnel. A pilot extremity DOELAP has been completed and routine testing is expected to begin in January 1994. It is expected that participation in the extremity program will be a regulatory requirement by January 1996.

  1. [Laboratory medicine in the obligatory postgraduate clinical training system--common clinical training program in the department of laboratory medicine in our prefectural medical university hospital].

    Science.gov (United States)

    Okamoto, Yasuyuki

    2003-04-01

    I propose a postgraduate common clinical training program to be provided by the department of laboratory medicine in our prefectural medical university hospital. The program has three purposes: first, mastering basic laboratory tests; second, developing the skills necessary to accurately interpret laboratory data; third, learning specific techniques in the field of laboratory medicine. For the first purpose, it is important that medical trainees perform testing of their own patients at bedside or in the central clinical laboratory. When testing at the central clinical laboratory, instruction by expert laboratory technicians is helpful. The teaching doctors in the department of laboratory medicine are asked to advise the trainees on the interpretation of data. Consultation will be received via interview or e-mail. In addition, the trainees can participate in various conferences, seminars, and meetings held at the central clinical laboratory. Finally, in order to learn specific techniques in the field of laboratory medicine, several special courses lasting a few months will be prepared. I think this program should be closely linked to the training program in internal medicine.

  2. Implementation of Good Clinical Laboratory Practice (GCLP) guidelines within the External Quality Assurance Program Oversight Laboratory (EQAPOL).

    Science.gov (United States)

    Todd, Christopher A; Sanchez, Ana M; Garcia, Ambrosia; Denny, Thomas N; Sarzotti-Kelsoe, Marcella

    2014-07-01

    The EQAPOL contract was awarded to Duke University to develop and manage global proficiency testing programs for flow cytometry-, ELISpot-, and Luminex bead-based assays (cytokine analytes), as well as create a genetically diverse panel of HIV-1 viral cultures to be made available to National Institutes of Health (NIH) researchers. As a part of this contract, EQAPOL was required to operate under Good Clinical Laboratory Practices (GCLP) that are traditionally used for laboratories conducting endpoint assays for human clinical trials. EQAPOL adapted these guidelines to the management of proficiency testing programs while simultaneously incorporating aspects of ISO/IEC 17043 which are specifically designed for external proficiency management. Over the first two years of the contract, the EQAPOL Oversight Laboratories received training, developed standard operating procedures and quality management practices, implemented strict quality control procedures for equipment, reagents, and documentation, and received audits from the EQAPOL Central Quality Assurance Unit. GCLP programs, such as EQAPOL, strengthen a laboratory's ability to perform critical assays and provide quality assessments of future potential vaccines. © 2013.

  3. In-situ thermal testing program strategy

    International Nuclear Information System (INIS)

    1995-06-01

    In the past year the Yucca Mountain Site Characterization Project has implemented a new Program Approach to the licensing process. The Program Approach suggests a step-wise approach to licensing in which the early phases will require less site information than previously planned and necessitate a lesser degree of confidence in the longer-term performance of the repository. Under the Program Approach, the thermal test program is divided into two principal phases: (1) short-term in situ tests (in the 1996 to 2000 time period) and laboratory thermal tests to obtain preclosure information, parameters, and data along with bounding information for postclosure performance; and (2) longer-term in situ tests to obtain additional data regarding postclosure performance. This effort necessitates a rethinking of the testing program because the amount of information needed for the initial licensing phase is less than previously planned. This document proposes a revised and consolidated in situ thermal test program (including supporting laboratory tests) that is structured to meet the needs of the Program Approach. A customer-supplier model is used to define the Project data needs. These data needs, along with other requirements, were then used to define a set of conceptual experiments that will provide the required data within the constraints of the Program Approach schedule. The conceptual thermal tests presented in this document represent a consolidation and update of previously defined tests that should result in a more efficient use of Project resources. This document focuses on defining the requirements and tests needed to satisfy the goal of a successful license application in 2001, should the site be found suitable

  4. [Statistical approach to evaluate the occurrence of out-of acceptable ranges and accuracy for antimicrobial susceptibility tests in inter-laboratory quality control program].

    Science.gov (United States)

    Ueno, Tamio; Matuda, Junichi; Yamane, Nobuhisa

    2013-03-01

    To evaluate the occurrence of out-of acceptable ranges and accuracy of antimicrobial susceptibility tests, we applied a new statistical tool to the Inter-Laboratory Quality Control Program established by the Kyushu Quality Control Research Group. First, we defined acceptable ranges of minimum inhibitory concentration (MIC) for broth microdilution tests and inhibitory zone diameter for disk diffusion tests on the basis of Clinical and Laboratory Standards Institute (CLSI) M100-S21. In the analysis, more than two out-of acceptable range results in the 20 tests were considered as not allowable according to the CLSI document. Of the 90 participating laboratories, 46 (51%) experienced one or more occurrences of out-of acceptable range results. Then, a binomial test was applied to each participating laboratory. The results indicated that the occurrences of out-of acceptable range results in the 11 laboratories were significantly higher when compared to the CLSI recommendation (allowable rate laboratory was statistically compared with zero using a Student's t-test. The results revealed that 5 of the 11 above laboratories reported erroneous test results that systematically drifted to the side of resistance. In conclusion, our statistical approach has enabled us to detect significantly higher occurrences and source of interpretive errors in antimicrobial susceptibility tests; therefore, this approach can provide us with additional information that can improve the accuracy of the test results in clinical microbiology laboratories.

  5. NedWind 25 Blade Testing at NREL for the European Standards Measurement and Testing Program

    Energy Technology Data Exchange (ETDEWEB)

    Larwood, S.; Musial, W.; Freebury, G.; Beattie, A.G.

    2001-04-19

    In the mid-90s the European community initiated the Standards, Measurements, and Testing (SMT) program to harmonize testing and measurement procedures in several industries. Within the program, a project was carried out called the European Wind Turbine Testing Procedure Development. The second part of that project, called Blade Test Methods and Techniques, included the United States and was devised to help blade-testing laboratories harmonize their testing methods. This report provides the results of those tests conducted by the National Renewable Energy Laboratory.

  6. Laboratory Cooperative Program: an assessment

    International Nuclear Information System (INIS)

    1979-11-01

    The Laboratory Cooperative Program (Lab Coop Program) was initiated by the US AEC over 20 years ago to promote the transfer of technical information from the national laboratories to the academic community utilizing the facilities and staff capabilities of the labs. Under the AEC, ERDA and DOE, the goals of the program have broadened gradually. Therefore, the program was examined to determine the extent to which it contributes to the current objectives of the DOE and to develop recommendations for any program changes. The assessment of the Lab Coop Program was based on a combination of review of program activity data and publications, review of general information regarding laboratory operations, and extensive interviews. The major findings of this evaluation were that: the program lacks a clear statement of purpose; program plans, priorities, and procedures are not explicit and operations tend to follow historical patterns; and the program is generally accepted as beneficial, but its benefits are difficult to quantify. It is recommended that the focus of the Lab Coop Program be limited and clearly defined, that performance plans be developed and measured against accomplishments, and that a national informational effort be initiated

  7. Laboratory Tests

    Science.gov (United States)

    ... Medical Devices Radiation-Emitting Products Vaccines, Blood & Biologics Animal & ... What are lab tests? Laboratory tests are medical devices that are intended for use on samples of blood, urine, or other tissues ...

  8. CDC’s Newborn Screening Program - Role of Laboratories

    Centers for Disease Control (CDC) Podcasts

    When newborn screening started in the U.S. 50 years ago, many questioned whether it was even possible to test every baby born in every state. Today, all states screen babies for at least 29 disorders that can be detected through laboratory testing. In this podcast, Dr. Carla Cuthbert talks about CDC’s Newborn Screening Quality Assurance Program and the role laboratories play in keeping babies healthy.

  9. 49 CFR 40.99 - How long does the laboratory retain specimens after testing?

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false How long does the laboratory retain specimens after testing? 40.99 Section 40.99 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.99 How...

  10. The performance test of NAA laboratory at radionuclide measure with low activity

    International Nuclear Information System (INIS)

    Sri Murniasih; Sukirno

    2016-01-01

    The performance test to measure the I-131 radionuclide activity has been carried out at CAST-NAA laboratory. The purpose of this activity is to know the performance of a laboratory in the testing of low radioactivity sample. The tested sample consists of the form I-131 radionuclide sources shaped thin plastic disk with a certain weight. Evaluation of laboratory performance test results carried out by the organizer of the program test appeal (PTKMR-BATAN). Evaluation results showed that testing of point source of the I-131 radionuclide with comparative method gives a good enough results with errors below 10%. The results of the performance test evaluation are useful as the external quality control to a testing method that is expected in NAA laboratory. (author)

  11. [Laboratory accreditation and proficiency testing].

    Science.gov (United States)

    Kuwa, Katsuhiko

    2003-05-01

    ISO/TC 212 covering clinical laboratory testing and in vitro diagnostic test systems will issue the international standard for medical laboratory quality and competence requirements, ISO 15189. This standard is based on the ISO/IEC 17025, general requirements for competence of testing and calibration laboratories and ISO 9001, quality management systems-requirements. Clinical laboratory services are essential to patient care and therefore should be available to meet the needs of all patients and clinical personnel responsible for human health care. If a laboratory seeks accreditation, it should select an accreditation body that operates according to this international standard and in a manner which takes into account the particular requirements of clinical laboratories. Proficiency testing should be available to evaluate the calibration laboratories and reference measurement laboratories in clinical medicine. Reference measurement procedures should be of precise and the analytical principle of measurement applied should ensure reliability. We should be prepared to establish a quality management system and proficiency testing in clinical laboratories.

  12. DOE standard: The Department of Energy Laboratory Accreditation Program for radiobioassay

    International Nuclear Information System (INIS)

    1998-12-01

    This technical standard describes the US Department of Energy Laboratory Accreditation Program (DOELAP) for Radiobioassay, for use by the US Department of Energy (DOE) and DOE Contractor radiobioassay programs. This standard is intended to be used in conjunction with the general administrative technical standard that describes the overall DOELAP accreditation process--DOE-STD-1111-98, Department of Energy Laboratory Accreditation Program Administration. This technical standard pertains to radiobioassay service laboratories that provide either direct or indirect (in vivo or in vitro) radiobioassay measurements in support of internal dosimetry programs at DOE facilities or for DOE and DOE contractors. Similar technical standards have been developed for other DOELAP dosimetry programs. This program consists of providing an accreditation to DOE radiobioassay programs based on successful completion of a performance-testing process and an on-site evaluation by technical experts. This standard describes the technical requirements and processes specific to the DOELAP Radiobioassay Accreditation Program as required by 10 CFR 835 and as specified generically in DOE-STD-1111-98

  13. FOOD SAFETY TESTING LABORATORY

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory develops screening assays, tests and modifies biosensor equipment, and optimizes food safety testing protocols for the military and civilian sector...

  14. ABACC's laboratory intercomparison program

    International Nuclear Information System (INIS)

    Almeida, Gevaldo L. de; Esteban, Adolfo; Almeida, Silvio G. de; Araujo, Radier M. de; Rocha, Zildete

    1996-01-01

    A Laboratory Intercomparison Program involving Brazilian and Argentine laboratories, with the special participation of New Brunswick Laboratory - DOE and IAEA Seibersdorf Safeguards Laboratory, was implanted by ABACC having as main purpose to qualify a network to provide analytical services to this Agency on its role as administrator of the Common System of Accountability and Control of Nuclear Materials. For the first round robin of this Program, 15 laboratories were invited to perform elemental analysis on UO 2 samples, by using any desired method. Thirteen confirmed the participation and 10 reported the results. After an evaluation of the results by using a Two-Way Variance Analysis applied to a nested error model, it was found that 5 of them deviate less than 0.1% from the reference value established for the UO 2 uranium contents, being thus situated within the limits adopted for the target values, while the remaining ones reach a maximal deviation of 0.44%. The outcome of this evaluation, was sent to the laboratories, providing them with a feedback to improve their performance by applying corrective actions to the detected sources of errors or bias related to the methods techniques and procedures. (author)

  15. Effects of earthquake induced rock shear on containment system integrity. Laboratory testing plan development

    International Nuclear Information System (INIS)

    Read, Rodney S.

    2011-07-01

    This report describes a laboratory-scale testing program plan to address the issue of earthquake induced rock shear effects on containment system integrity. The document contains a review of relevant literature from SKB covering laboratory testing of bentonite clay buffer material, scaled analogue tests, and the development of related material models to simulate rock shear effects. The proposed testing program includes standard single component tests, new two-component constant volume tests, and new scaled analogue tests. Conceptual drawings of equipment required to undertake these tests are presented along with a schedule of tests. The information in this document is considered sufficient to engage qualified testing facilities, and to guide implementation of laboratory testing of rock shear effects. This document was completed as part of a collaborative agreement between SKB and Nuclear Waste Management Organization (NWMO) in Canada

  16. Effects of earthquake induced rock shear on containment system integrity. Laboratory testing plan development

    Energy Technology Data Exchange (ETDEWEB)

    Read, Rodney S. (RSRead Consulting Inc. (Canada))

    2011-07-15

    This report describes a laboratory-scale testing program plan to address the issue of earthquake induced rock shear effects on containment system integrity. The document contains a review of relevant literature from SKB covering laboratory testing of bentonite clay buffer material, scaled analogue tests, and the development of related material models to simulate rock shear effects. The proposed testing program includes standard single component tests, new two-component constant volume tests, and new scaled analogue tests. Conceptual drawings of equipment required to undertake these tests are presented along with a schedule of tests. The information in this document is considered sufficient to engage qualified testing facilities, and to guide implementation of laboratory testing of rock shear effects. This document was completed as part of a collaborative agreement between SKB and Nuclear Waste Management Organization (NWMO) in Canada

  17. 42 CFR 410.32 - Diagnostic x-ray tests, diagnostic laboratory tests, and other diagnostic tests: Conditions.

    Science.gov (United States)

    2010-10-01

    ... Procedural Terminology published by the American Medical Association. (3) Levels of supervision. Except where... & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM SUPPLEMENTARY MEDICAL INSURANCE (SMI) BENEFITS Medical and Other Health Services § 410.32 Diagnostic x-ray tests, diagnostic laboratory...

  18. Choosing the right laboratory: a review of clinical and forensic toxicology services for urine drug testing in pain management.

    Science.gov (United States)

    Reisfield, Gary M; Goldberger, Bruce A; Bertholf, Roger L

    2015-01-01

    Urine drug testing (UDT) services are provided by a variety of clinical, forensic, and reference/specialty laboratories. These UDT services differ based on the principal activity of the laboratory. Clinical laboratories provide testing primarily focused on medical care (eg, emergency care, inpatients, and outpatient clinics), whereas forensic laboratories perform toxicology tests related to postmortem and criminal investigations, and drug-free workplace programs. Some laboratories now provide UDT specifically designed for monitoring patients on chronic opioid therapy. Accreditation programs for clinical laboratories have existed for nearly half a century, and a federal certification program for drug-testing laboratories was established in the 1980s. Standards of practice for forensic toxicology services other than workplace drug testing have been established in recent years. However, no accreditation program currently exists for UDT in pain management, and this review considers several aspects of laboratory accreditation and certification relevant to toxicology services, with the intention to provide guidance to clinicians in their selection of the appropriate laboratory for UDT surveillance of their patients on opioid therapy.

  19. Accelerated leach test development program

    International Nuclear Information System (INIS)

    Fuhrmann, M.; Pietrzak, R.F.; Heiser, J.; Franz, E.M.; Colombo, P.

    1990-11-01

    In FY 1989, a draft accelerated leach test for solidified waste was written. Combined test conditions that accelerate leaching were validated through experimental and modeling efforts. A computer program was developed that calculates test results and models leaching mechanisms. This program allows the user to determine if diffusion controls leaching and, if this is the case, to make projections of releases. Leaching mechanisms other than diffusion (diffusion plus source term partitioning and solubility limited leaching) are included in the program is indicators of other processes that may control leaching. Leach test data are presented and modeling results are discussed for laboratory scale waste forms composed of portland cement containing sodium sulfate salt, portland cement containing incinerator ash, and vinyl ester-styrene containing sodium sulfate. 16 refs., 38 figs., 5 tabs

  20. The Los Alamos National Laboratory Environmental Restoration Program

    International Nuclear Information System (INIS)

    Krueger, J.W.

    1990-01-01

    The LANL Environmental Restoration (ER) Program Office, established in October 1989, is faced with the challenge of assessing and cleaning up nearly 1,8000 potentially hazardous waste sites according to an aggressive corrective action schedule that the Environmental Protection Agency (EPA) mandated on May 23, 1990, in a Resource, Conservation, and Recovery Act (RCRA) Part B Permit. To maximize program efficiency, the ER Program Office will implement a unique management approach designed to maximize the use of laboratory technical expertise. The Installation Work Plan, which provides a blueprint for the program, has been submitted to EPA for review and approval. A work plan for characterization of Technical Area 21, an early plutonium processing facility, is also nearing completion. The feasibility of an expedited cleanup of the Laboratory's worst hazardous waste release has been modelled using a computer code originally developed by LANL to assist the nuclear weapons testing program. A sophisticated Geographic Information System has been implemented to assist in data management and presentation, and the design of a Mixed Waste Disposal Facility is underway. 6 refs., 2 figs

  1. Laboratory Animal Sciences Program (LASP)

    Data.gov (United States)

    Federal Laboratory Consortium — The Laboratory Animal Sciences Program (LASP) is a comprehensive resource for scientists performing animal-based research to gain a better understanding of cancer,...

  2. RESULTS OF THE FIRST MI-171A2 FLYING LABORATORY TEST PHASE

    OpenAIRE

    V. A. Ivchin; K. Y. Samsonov

    2014-01-01

    The present publication describes the results of the first stage of the flying laboratory (Mi-171 helicopter) flight tests performed at Mil Moscow Helicopter Plant, JSC facilities. Main rotor components with blades made of polymer composite materials and X-type tail rotor were tested on the Mi-171 № 14987, flying laboratory, under Mi-171A Helicopter Retrofit Program.

  3. Recommended procedures for performance testing of radiobioassay laboratories: Volume 2, In vitro samples

    International Nuclear Information System (INIS)

    Fenrick, H.W.; MacLellan, J.A.

    1988-11-01

    Draft American National Standards Institute (ANSI) Standard N13.30 (Performance Criteria for Radiobioassay) was developed for the US Department of Energy and the US Nuclear Regulatory Commission to help ensure that bioassay laboratories provide accurate and consistent results. The draft standard specifies the criteria for defining the procedures necessary to establish a bioassay performance-testing laboratory and program. The bioassay testing laboratory will conduct tests to evaluate the performance of service laboratories. Pacific Northwest Laboratory helped develop testing procedures as part of an effort to evaluate the performance criteria by testing the existing measurement capabilities of various bioassay laboratories. This report recommends guidelines for the preparation, handling, storage, distribution, shipping, and documentation of in vitro test samples (artificial urine and fecal matter) for indirect bioassay. The data base and recommended records system for documenting radiobioassay performance at the service laboratories are also presented. 8 refs., 3 tabs

  4. PIGMI program at the Los Alamos Scientific Laboratory

    International Nuclear Information System (INIS)

    Stovall, J.E.

    1980-09-01

    The PIGMI Program has completed 3-1/2 yr of a project to develop the technology for the optimal pion generator for medical irradiations (PIGMI). The major accomplishments under the program include completion of the injector beam measurements; completion of the 440-MHz radio-frequency (rf) power source; assembly and test of the alternating phase focusing accelerator section; development of the rf-quadrupole (RFQ) beam-dynamics program, PARMTEQ; design, fabrication, assembly, and test of the RFQ accelerator; final decision on low-energy configuration for PIGMI; assembly of the drift-tube linac section of the PIGMI Prototype; completion of sample set of permanent magnet quadrupoles; optimization of the disk-and-washer (DAW) cavity geometry; fabrication of model cavities of the DAW; final decision on DAW support geometry; acquisition of additional laboratory space for the DAW power test; partial assembly of the 1320-MHz rf power source for the DAW test; and pion channel design studies

  5. A Laboratory Safety Program at Delaware.

    Science.gov (United States)

    Whitmyre, George; Sandler, Stanley I.

    1986-01-01

    Describes a laboratory safety program at the University of Delaware. Includes a history of the program's development, along with standard safety training and inspections now being implemented. Outlines a two-day laboratory safety course given to all graduate students and staff in chemical engineering. (TW)

  6. RESULTS OF THE FIRST MI-171A2 FLYING LABORATORY TEST PHASE

    Directory of Open Access Journals (Sweden)

    V. A. Ivchin

    2014-01-01

    Full Text Available The present publication describes the results of the first stage of the flying laboratory (Mi-171 helicopter flight tests performed at Mil Moscow Helicopter Plant, JSC facilities. Main rotor components with blades made of polymer composite materials and X-type tail rotor were tested on the Mi-171 № 14987, flying laboratory, under Mi-171A Helicopter Retrofit Program.

  7. Productivity of Veterans Health Administration laboratories: a College of American Pathologists Laboratory Management Index Program (LMIP) study.

    Science.gov (United States)

    Valenstein, Paul N; Wang, Edward; O'Donohue, Tom

    2003-12-01

    The Veterans Health Administration (VA) operates the largest integrated laboratory network in the United States. To assess whether the unique characteristics of VA laboratories impact efficiency of operations, we compared the productivity of VA and non-VA facilities. Financial and activity data were prospectively collected from 124 VA and 131 non-VA laboratories enrolled in the College of American Pathologists Laboratory Management Index Program (LMIP) during 2002. In addition, secular trends in 5 productivity ratios were calculated for VA and non-VA laboratories enrolled in LMIP from 1997 through 2002. Veterans Health Administration and non-VA facilities did not differ significantly in size. Inpatients accounted for a lower percentage of testing at VA facilities than non-VA facilities (21.7% vs 37.3%; P benefits; P depreciation, and maintenance than their non-VA counterparts (all P <.001), resulting in lower overall cost per on-site test result (2.64 dollars vs 3.40 dollars; P <.001). Cost per referred (sent-out) test did not differ significantly between the 2 groups. Analysis of 6-year trends showed significant increases in both VA (P <.001) and non-VA (P =.02) labor productivity (on-site tests/total FTE). Expenses at VA laboratories for labor per test, consumables per test, overall expense per test, and overall laboratory expense per discharge decreased significantly during the 6-year period (P <.001), while in non-VA facilities the corresponding ratios showed no significant change. Overall productivity of VA laboratories is superior to that of non-VA facilities enrolled in LMIP. The principal advantages enjoyed by the VA are higher-than-average labor productivity (tests/FTE) and lower-than-average consumable expenses.

  8. Laboratory testing in hyperthyroidism.

    Science.gov (United States)

    Grebe, Stefan K G; Kahaly, George J

    2012-09-01

    The clinical diagnosis of hypo- or hyperthyroidism is difficult (full text available online: http://education.amjmed.com/pp1/272). Clinical symptoms and signs are often non-specific, and there is incomplete correlation between structural and functional thyroid gland changes. Laboratory testing is therefore indispensible in establishing the diagnosis of thyrotoxicosis. Similar considerations apply to treatment monitoring. Laboratory testing also plays a crucial role in establishing the most likely cause for a patient's hyperthyroidism. Finally, during pregnancy, when isotopic scanning is relatively contraindicated and ultrasound is more difficult to interpret, laboratory testing becomes even more important. Copyright © 2012. Published by Elsevier Inc.

  9. HPS instrument calibration laboratory accreditation program

    Energy Technology Data Exchange (ETDEWEB)

    Masse, F.X; Eisenhower, E.H.; Swinth, K.L.

    1993-12-31

    The purpose of this paper is to provide an accurate overview of the development and structure of the program established by the Health Physics Society (HPS) for accrediting instrument calibration laboratories relative to their ability to accurately calibrate portable health physics instrumentation. The purpose of the program is to provide radiation protection professionals more meaningful direct and indirect access to the National Institute of Standards and Technology (NIST) national standards, thus introducing a means for improving the uniformity, accuracy, and quality of ionizing radiation field measurements. The process is designed to recognize and document the continuing capability of each accredited laboratory to accurately perform instrument calibration. There is no intent to monitor the laboratory to the extent that each calibration can be guaranteed by the program; this responsibility rests solely with the accredited laboratory.

  10. CDC’s Newborn Screening Program - Role of Laboratories

    Centers for Disease Control (CDC) Podcasts

    2013-09-03

    When newborn screening started in the U.S. 50 years ago, many questioned whether it was even possible to test every baby born in every state. Today, all states screen babies for at least 29 disorders that can be detected through laboratory testing. In this podcast, Dr. Carla Cuthbert talks about CDC’s Newborn Screening Quality Assurance Program and the role laboratories play in keeping babies healthy.  Created: 9/3/2013 by National Center for Environmental Health (NCEH).   Date Released: 9/3/2013.

  11. The Cost-Effective Laboratory: Implementation of Economic Evaluation of Laboratory Testing

    Directory of Open Access Journals (Sweden)

    Bogavac-Stanojevic Natasa

    2017-09-01

    Full Text Available Laboratory testing as a part of laboratory in vitro diagnostic (IVD has become required tool in clinical practice for diagnosing, monitoring and prognosis of diseases, as well as for prediction of treatment response. The number of IVD tests available in laboratory practice has increased over the past decades and is likely to further increase in the future. Consequently, there is growing concern about the overutilization of laboratory tests and rising costs for laboratory testing. It is estimated that IVD accounts for between 1.4 and 2.3% of total healthcare expenditure and less than 5% of total hospital cost (Lewin Group report. These costs are rather low when compared to pharmaceuticals and medical aids which account for 15 and 5%, respectively. On the other hand, IVD tests play an important role in clinical practice, as they influence from 60% to 70% of clinical decision-making. Unfortunately, constant increases in healthcare spending are not directly related to healthcare benefit. Since healthcare resources are limited, health payers are interested whether the benefits of IVD tests are actually worth their cost. Many articles have introduced frameworks to assess the economic value of IVD tests. The most appropriate tool for quantitative assessment of their economic value is cost-effectiveness (CEA and cost-utility (CUA analysis. The both analysis determine cost in terms of effectiveness or utilities (combine quantity and quality of life of new laboratory test against its alternative. On the other hand, some investigators recommended calculation of laboratory test value as product of two ratios: Laboratory test value = (Technical accuracy/Turnaround time × (Utility/Costs. Recently, some researches used multicriteria decision analysis which allows comparison of diagnostic strategies in terms of benefits, opportunities, costs and risks. All analyses are constructed to identify laboratory test that produce the greatest healthcare benefit with

  12. Conceptual plan: Two-Phase Flow Laboratory Program for the Waste Isolation Pilot Plant

    International Nuclear Information System (INIS)

    Howarth, S.M.

    1993-07-01

    The Salado Two-Phase Flow Laboratory Program was established to address concerns regarding two-phase flow properties and to provide WIPP-specific, geologically consistent experimental data to develop more appropriate correlations for Salado rock to replace those currently used in Performance Assessment models. Researchers in Sandia's Fluid Flow and Transport Department originally identified and emphasized the need for laboratory measurements of Salado threshold pressure and relative permeability. The program expanded to include the measurement of capillary pressure, rock compressibility, porosity, and intrinsic permeability and the assessment of core damage. Sensitivity analyses identified the anhydrite interbed layers as the most likely path for the dissipation of waste-generated gas from waste-storage rooms because of their relatively high permeability. Due to this the program will initially focus on the anhydrite interbed material. The program may expand to include similar rock and flow measurements on other WIPP materials including impure halite, pure halite, and backfill and seal materials. This conceptual plan presents the scope, objectives, and historical documentation of the development of the Salado Two-Phase Flow Program through January 1993. Potential laboratory techniques for assessing core damage and measuring porosity, rock compressibility, capillary and threshold pressure, permeability as a function of stress, and relative permeability are discussed. Details of actual test designs, test procedures, and data analysis are not included in this report, but will be included in the Salado Two-Phase Flow Laboratory Program Test Plan pending the results of experimental and other scoping activities in FY93

  13. Integrated Data Collection Analysis (IDCA) Program - SSST Testing Methods

    Energy Technology Data Exchange (ETDEWEB)

    Sandstrom, Mary M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Brown, Geoffrey W. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Preston, Daniel N. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Pollard, Colin J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Warner, Kirstin F. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Remmers, Daniel L. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Sorensen, Daniel N. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Whinnery, LeRoy L. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Phillips, Jason J. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Shelley, Timothy J. [Bureau of Alcohol, Tobacco and Firearms (ATF), Huntsville, AL (United States); Reyes, Jose A. [Applied Research Associates, Tyndall AFB, FL (United States); Hsu, Peter C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Reynolds, John G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2013-03-25

    The Integrated Data Collection Analysis (IDCA) program is conducting a proficiency study for Small- Scale Safety and Thermal (SSST) testing of homemade explosives (HMEs). Described here are the methods used for impact, friction, electrostatic discharge, and differential scanning calorimetry analysis during the IDCA program. These methods changed throughout the Proficiency Test and the reasons for these changes are documented in this report. The most significant modifications in standard testing methods are: 1) including one specified sandpaper in impact testing among all the participants, 2) diversifying liquid test methods for selected participants, and 3) including sealed sample holders for thermal testing by at least one participant. This effort, funded by the Department of Homeland Security (DHS), is putting the issues of safe handling of these materials in perspective with standard military explosives. The study is adding SSST testing results for a broad suite of different HMEs to the literature. Ultimately the study will suggest new guidelines and methods and possibly establish the SSST testing accuracies needed to develop safe handling practices for HMEs. Each participating testing laboratory uses identical test materials and preparation methods wherever possible. The testing performers involved are Lawrence Livermore National Laboratory (LLNL), Los Alamos National Laboratory (LANL), Indian Head Division, Naval Surface Warfare Center, (NSWC IHD), Sandia National Laboratories (SNL), and Air Force Research Laboratory (AFRL/RXQL). These tests are conducted as a proficiency study in order to establish some consistency in test protocols, procedures, and experiments and to compare results when these testing variables cannot be made consistent.

  14. 10 CFR 26.153 - Using certified laboratories for testing urine specimens.

    Science.gov (United States)

    2010-01-01

    ... Workplace Drug Testing Programs [published in the Federal Register on April 11, 1988 (53 FR 11970), and as... current certification status of laboratories is available from the Division of Workplace Programs, Center... relationship with the licensee's or other entity's MRO(s) that may be construed as a potential conflict of...

  15. Sandia National Laboratories: Careers: Special Programs

    Science.gov (United States)

    Program Master's Fellowship Program Wounded Warrior Career Development Program Careers Special Programs Special career opportunities for select individuals Join Sandia's workforce while receiving support and Laboratories' Affirmative Action Plan. Learn more about MFP. Wounded Warrior Career Development Program U.S

  16. Plutonium Immobilization Program cold pour tests

    International Nuclear Information System (INIS)

    Hovis, G.L.; Stokes, M.W.; Smith, M.E.; Wong, J.W.

    1999-01-01

    The Plutonium Immobilization Program (PIP) is a joint venture between the Savannah River Site, Lawrence Livermore National Laboratory, Argonne National Laboratory, and Pacific Northwest National Laboratory to carry out the disposition of excess weapons-grade plutonium. This program uses the can-in-canister (CIC) approach. CIC involves encapsulating plutonium in ceramic forms (or pucks), placing the pucks in sealed stainless steel cans, placing the cans in long cylindrical magazines, latching the magazines to racks inside Defense Waste Processing Facility (DWPF) canisters, and filling the DWPF canisters with high-level waste glass. This process puts the plutonium in a stable form and makes it attractive for reuse. At present, the DWPF pours glass into empty canisters. In the CIC approach, the addition of a stainless steel rack, magazines, cans, and ceramic pucks to the canisters introduces a new set of design and operational challenges: All of the hardware installed in the canisters must maintain structural integrity at elevated (molten-glass) temperatures. This suggests that a robust design is needed. However, the amount of material added to the DWPF canister must be minimized to prevent premature glass cooling and excessive voiding caused by a large internal thermal mass. High metal temperatures, minimizing thermal mass, and glass flow paths are examples of the types of technical considerations of the equipment design process. To determine the effectiveness of the design in terms of structural integrity and glass-flow characteristics, full-scale testing will be conducted. A cold (nonradioactive) pour test program is planned to assist in the development and verification of a baseline design for the immobilization canister to be used in the PIP process. The baseline design resulting from the cold pour test program and CIC equipment development program will provide input to Title 1 design for second-stage immobilization. The cold pour tests will be conducted in two

  17. Understanding Laboratory Tests

    Science.gov (United States)

    ... and Drug Administration (FDA) regulates the development and marketing of all laboratory tests that use test kits ... Cancer.gov en español Multimedia Publications Site Map Digital Standards for NCI Websites POLICIES Accessibility Comment Policy ...

  18. Metallurgical Laboratory and Components Testing

    Data.gov (United States)

    Federal Laboratory Consortium — In the field of metallurgy, TTC is equipped to run laboratory tests on track and rolling stock components and materials. The testing lab contains scanning-electron,...

  19. The Brookhaven National Laboratory Accelerator Test Facility

    International Nuclear Information System (INIS)

    Batchelor, K.

    1992-01-01

    The Brookhaven National Laboratory Accelerator Test Facility comprises a 50 MeV traveling wave electron linear accelerator utilizing a high gradient, photo-excited, raidofrequency electron gun as an injector and an experimental area for study of new acceleration methods or advanced radiation sources using free electron lasers. Early operation of the linear accelerator system including calculated and measured beam parameters are presented together with the experimental program for accelerator physics and free electron laser studies

  20. Fuel cells for transportation program: FY1997 national laboratory annual report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    The Department of Energy (DOE) Fuel Cells for Transportation Program is structured to effectively implement the research and development (R and D) required for highly efficient, low or zero emission fuel cell power systems to be a viable replacement for the internal combustion engine in automobiles. The Program is part of the Partnership for a New Generation of Vehicles (PNGV), a government-industry initiative aimed at development of an 80 mile-per-gallon vehicle. This Annual Report summarizes the technical accomplishments of the laboratories during 1997. Participants include: Argonne National Laboratory (ANL), Brookhaven National Laboratory (BNL), Lawrence Berkeley National Laboratory (LBNL), Los Alamos National Laboratory (LANL), Oak Ridge National Laboratory (ORNL), Pacific Northwest National Laboratory (PNNL), and the National Renewable Energy Laboratory (NREL). During 1997, the laboratory R and D included one project on solid oxide fuel cells; this project has since been terminated to focus Department resources on PEM fuel cells. The technical component of this report is divided into five key areas: fuel cell stack research and development; fuel processing; fuel cell modeling, testing, and evaluation; direct methanol PEM fuel cells; and solid oxide fuel cells.

  1. US/Russian laboratory-to-laboratory MPC ampersand A Program at the VNIITF Institute, Chelyabinsk-70 May 1996

    International Nuclear Information System (INIS)

    Tsygankov, G.; Churikov, Y.; Teryokhin, V.

    1996-01-01

    The AR Russian Institute of Technical Physics (VNIITF), also called Chelyabinsk-70, is one of two Russian federal nuclear centers established to design, test and support nuclear weapons throughout their life cycle. The site contains research facilities which use nuclear materials, two experimental plants which manufacture prototype samples for nuclear weapons, and a site for various ground tests. Chelyabinsk-70 also has cooperative relationships with the major nuclear materials production facilities in the Urals region of Russia. Chelyabinsk-70 has been participating in the US/Russian Laboratory-to-laboratory cooperative program for approximately one year. Six US Department of Energy Laboratories are carrying out a program of cooperation with VNIITF to improve the capabilities and facilities for nuclear materials protection, control, and accounting (MPC ampersand A) at VNIITF. A Safeguards Effectiveness Evaluation Workshop was conducted at VNIITF in July, 1995. Enhanced safeguards systems are being implemented, initially at a reactor test area that contains three pulse reactors. Significant improvements to physical security and access control systems are under way. C-70 is developing an extensive computerized system that integrates the physical security alarm station with elements of the nuclear material control system. The existing systems will be augmented with Russian and US technologies. This paper will describe the on-going activities and describe the cooperative effort between the Lawrence Livermore, Los Alamos, Sandia, Oak Ridge, Pacific Northwest, and Brookhaven US Department of Energy National Laboratories and VNIITF

  2. Zero-gravity cloud physics laboratory: Experiment program definition and preliminary laboratory concept studies

    Science.gov (United States)

    Eaton, L. R.; Greco, E. V.

    1973-01-01

    The experiment program definition and preliminary laboratory concept studies on the zero G cloud physics laboratory are reported. This program involves the definition and development of an atmospheric cloud physics laboratory and the selection and delineations of a set of candidate experiments that must utilize the unique environment of zero gravity or near zero gravity.

  3. Test plan for preparing the Rapid Transuranic Monitoring Laboratory for field deployment

    International Nuclear Information System (INIS)

    McIsaac, C.V.; Sill, C.W.; Gehrke, R.J.; Killian, E.W.; Watts, K.D.

    1994-04-01

    This plan describes experimental work that will be performed during fiscal year 1994 to prepare the Rapid Transuranic Monitoring Laboratory (RTML) for routine field use by US Department of Energy (DOE) Environmental Restoration and Waste Management programs. The RTML is a mobile, field-deployable laboratory developed at the Idaho National Engineering Laboratory (INEL) that provides a rapid, cost-effective means of characterizing and monitoring radioactive waste remediation sites for low-level radioactive contaminants. Analytical instruments currently installed in the RTML include an extended-range, germanium photon analysis spectrometer with an automatic sample changer; two, large-area, ionization chamber alpha spectrometers; and four alpha continuous air monitors. The RTML was field tested at the INEL during June 1993 in conjunction with the Buried Waste Integrated Demonstration's remote retrieval demonstration. The major tasks described in this test plan are to (a) evaluate the beta detectors for use in screening soil samples for 90 Sr, (b) upgrade the alpha spectral analysis software programs, and (c) upgrade the photon spectral analysis software programs

  4. Operational evaluation of rapid diagnostic testing for Ebola Virus Disease in Guinean laboratories.

    Directory of Open Access Journals (Sweden)

    Amanda VanSteelandt

    Full Text Available Rapid Diagnostic Tests (RDTs for Ebola Virus Disease (EVD at the point of care have the potential to increase access and acceptability of EVD testing and the speed of patient isolation and secure burials for suspect cases. A pilot program for EVD RDTs in high risk areas of Guinea was introduced in October 2015. This paper presents concordance data between EVD RDTs and PCR testing in the field as well as an assessment of the acceptability, feasibility, and quality assurance of the RDT program.Concordance data were compiled from laboratory surveillance databases. The operational measures of the laboratory-based EVD RDT program were evaluated at all 34 sentinel sites in Guinea through: (1 a technical questionnaire filled by the lab technicians who performed the RDTs, (2 a checklist filled by the evaluator during the site visits, and (3 direct observation of the lab technicians performing the quality control test. Acceptability of the EVD RDT was good for technicians, patients, and families although many technicians (69.8% expressed concern for their safety while performing the test. The feasibility of the program was good based on average technician knowledge scores (6.6 out of 8 but basic infrastructure, equipment, and supplies were lacking. There was much room for improvement in quality assurance of the program.The implementation of new diagnostics in weak laboratory systems requires general training in quality assurance, biosafety and communication with patients in addition to specific training for the new test. Corresponding capacity building in terms of basic equipment and a long-term commitment to transfer supervision and quality improvement to national public health staff are necessary for successful implementation.

  5. Design and construction of the SSCL magnet test laboratory cryogenic systems

    International Nuclear Information System (INIS)

    Freeman, M.A.; Kobel, T.A.

    1992-01-01

    The intent of this document is to provide a brief summary of the execution, by Process Systems International, Inc. (PSI), of the Design and Construction of the SSCL Magnet Test Laboratory Cryogenic Systems. This $30 million project requires the expenditure of over 200,000 manhours and the procurement of $17 million in materials within a two year period. SSC magnets will be performance tested at the Magnet Test Laboratory (MTL) and the Accelerator System String Test (ASST) facility under conditions simulating the environment of the SSC main ring. The cryogenic system consists of test stands (five for MTL, one for ASST) and the associated equipment including cryogenic storage, purification, thermal conditioning, and helium refrigeration necessary to support the test program

  6. Test Cost and Test Accuracy in Clinical Laboratories in Kampala, Uganda.

    Science.gov (United States)

    Amukele, Timothy K; Jones, Robert; Elbireer, Ali

    2018-04-25

    To assess the accuracy and costs of laboratory tests in Kampala, Uganda. A random selection of 78 laboratories tested external quality assurance samples at market rates. There were 40 moderate- to high-complexity and 38 low-complexity laboratories. Four percent (3/78) of these laboratories were accredited and 94% (73/78) were private. The 40 moderate- to high-complexity laboratories performed malaria blood smear, urine human chorionic gonadotropin (hCG), human immunodeficiency virus (HIV), syphilis, glucose, and three-panel tests: CBC, liver function tests, and kidney function tests. The 38 low-complexity laboratories performed malaria blood smear, urine hCG, and syphilis testing only. Hematology, HIV, syphilis, and malarial proficiency testing samples were prepared by accredited laboratories in Kampala. All other samples were provided by the Royal College of Pathologists of Australia. 77.1% of all results were accurate (met target values). It varied widely by laboratory (50%-100%), test identity (malaria blood smear, 96%; serum urea nitrogen, 38%), and test type (quantitative: 66% [31%-89%], qualitative: 91% [68%-97%]). Test prices varied by up to 3,600%, and there was no correlation between test cost and accuracy (r2 = 0.02). There were large differences in accuracy and price across laboratories in Kampala. Price was not associated with quality.

  7. Laboratory automation in a functional programming language.

    Science.gov (United States)

    Runciman, Colin; Clare, Amanda; Harkness, Rob

    2014-12-01

    After some years of use in academic and research settings, functional languages are starting to enter the mainstream as an alternative to more conventional programming languages. This article explores one way to use Haskell, a functional programming language, in the development of control programs for laboratory automation systems. We give code for an example system, discuss some programming concepts that we need for this example, and demonstrate how the use of functional programming allows us to express and verify properties of the resulting code. © 2014 Society for Laboratory Automation and Screening.

  8. U.S./Russian Laboratory-to-Laboratory MPC ampersand A Program at the VNIITF Institute, Chelyabinsk-70

    International Nuclear Information System (INIS)

    Teryohin, V.; Tzygankov, G.; Blasy, J.

    1995-07-01

    The All Russian Institute of Technical Physics (VNIITF) is one of the major sites in the nuclear weapons complex in Russia. The site contains a number of research facilities which use nuclear material as well as facilities active in disassembly and disposition of nuclear weapons. Chelyabinsk-70 (C-70) also has ties to the major nuclear materials production facilities in the Urals region of Russia. Under the U.S./Russian Laboratory -to- Laboratory cooperative program, enhanced safeguards systems are being implemented, initially at a reactor test area that contains two pulse reactors and a nuclear material storage facility. C-70 is developing an extensive computerized system that integrates the physical security alarm station with elements of the nuclear material control system. Under the Lab-to-Lab program, the existing systems will bi augmented with Russian and US technologies. The integrated MPC ampersand A system for the test facilities will be demonstrated to US and Russian audiences when completed and follow-on work at additional C-70 facilities will be identified. This paper will describe the on-going activities and describe the cooperative effort between the Lawrence Livermore, Los Alamos, Sandia, Oak Ridge, Pacific Northwest, and Brookhaven US Department of Energy National Laboratories in support of VNIITF

  9. U.S./Russian laboratory-to-laboratory MPC and A program at the VNIITF Institute, Chelyabinsk-70

    International Nuclear Information System (INIS)

    Teryohin, V.; Tzygankov, G.; Blasy, J.

    1996-01-01

    The All Russian Institute of Technical Physics (VNIITF) is one of the major sites in the nuclear weapons complex in Russia. The site contains a number of research facilities which use nuclear material as well as facilities active in disassembly and disposition of nuclear weapons. Chelyabinsk-70 (C-70) also has ties to the major nuclear materials production facilities in the Urals region of Russia. Under the US/Russian Laboratory-to-Laboratory cooperative program, enhanced safeguards systems are being implemented, initially at a reactor test area that contains two pulse reactors and a nuclear material storage facility. C-70 is developing an extensive computerized system that integrates the physical security alarm station with elements of the nuclear material control system. Under the Lab-to-Lab program, the existing systems will be augmented with Russian and US technologies. The integrated MPC and A system for the test facilities will be demonstrated to US and Russian audiences when completed and follow-on work at additional C-70 facilities will be identified. This paper will describe the on-going activities and describe the cooperative effort between the Lawrence Livermore, Los Alamos, Sandia, Oak Ridge, Pacific Northwest, and Brookhaven US Department of Energy National Laboratories in support of VNIITF

  10. Laboratory quality assurance and its role in the safeguards analytical laboratory evaluation (SALE) program

    International Nuclear Information System (INIS)

    Delvin, W.L.; Pietri, C.E.

    1981-07-01

    Since the late 1960's, strong emphasis has been given to quality assurance in the nuclear industry, particularly to that part involved in nuclear reactors. This emphasis has had impact on the analytical chemistry laboratory because of the importance of analytical measurements in the certification and acceptance of materials used in the fabrication and construction of reactor components. Laboratory quality assurance, in which the principles of quality assurance are applied to laboratory operations, has a significant role to play in processing, fabrication, and construction programs of the nuclear industry. That role impacts not only process control and material certification, but also safeguards and nuclear materials accountability. The implementation of laboratory quality assurance is done through a program plan that specifies how the principles of quality assurance are to be applied. Laboratory quality assurance identifies weaknesses and deficiencies in laboratory operations and provides confidence in the reliability of laboratory results. Such confidence in laboratory measurements is essential to the proper evaluation of laboratories participating in the Safeguards Analytical Laboratory Evaluation (SALE) Program

  11. Summary of microsatellite instability test results from laboratories participating in proficiency surveys: proficiency survey results from 2005 to 2012.

    Science.gov (United States)

    Boyle, Theresa A; Bridge, Julia A; Sabatini, Linda M; Nowak, Jan A; Vasalos, Patricia; Jennings, Lawrence J; Halling, Kevin C

    2014-03-01

    The College of American Pathologists surveys are the largest laboratory peer comparison programs in the world. These programs allow laboratories to regularly evaluate their performance and improve the accuracy of the patient test results they provide. Proficiency testing is offered twice a year to laboratories performing microsatellite instability testing. These surveys are designed to emulate clinical practice, and some surveys have more challenging cases to encourage the refinement of laboratory practices. This report summarizes the results and trends in microsatellite instability proficiency testing from participating laboratories from the inception of the program in 2005 through 2012. We compiled and analyzed data for 16 surveys of microsatellite instability proficiency testing during 2005 to 2012. The number of laboratories participating in the microsatellite instability survey has more than doubled from 42 to 104 during the 8 years analyzed. An average of 95.4% of the laboratories correctly classified each of the survey test samples from the 2005A through 2012B proficiency challenges. In the 2011B survey, a lower percentage of laboratories (78.4%) correctly classified the specimen, possibly because of overlooking subtle changes of microsatellite instability and/or failing to enrich the tumor content of the specimen to meet the limit of detection of their assay. In general, laboratories performed well in microsatellite instability testing. This testing will continue to be important in screening patients with colorectal and other cancers for Lynch syndrome and guiding the management of patients with sporadic colorectal cancer.

  12. Lawrence Berkeley Laboratory Affirmative Action Program. Revised

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-06-01

    The Lawrence Berkeley Laboratory`s Affirmative Action Program (AAP) serves as a working document that describes current policies, practices, and results in the area of affirmative action. It represents the Laboratory`s framework for an affirmative approach to increasing the representation of people of color and women in segments of our work force where they have been underrepresented and taking action to increase the employment of persons with disabilities and special disabled and Vietnam era veterans. The AAP describes the hierarchy of responsibility for Laboratory affirmative action, the mechanisms that exist for full Laboratory participation in the AAP, the policies and procedures governing recruitment at all levels, the Laboratory`s plan for monitoring, reporting, and evaluating affirmative action progress, and a description of special affirmative action programs and plans the Laboratory has used and will use in its efforts to increase the representation and retention of groups historically underrepresented in our work force.

  13. INTER LABORATORY COMBAT HELMET BLUNT IMPACT TEST METHOD COMPARISON

    Science.gov (United States)

    2018-03-26

    data by Instrumentation for Impact  Test , SAE standard J211‐1 [4]. Although the entire curve is collected, the interest of this  project  team  solely...HELMET BLUNT IMPACT TEST METHOD COMPARISON by Tony J. Kayhart Charles A. Hewitt and Jonathan Cyganik March 2018 Final...INTER-LABORATORY COMBAT HELMET BLUNT IMPACT TEST METHOD COMPARISON 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR

  14. ASVCP quality assurance guidelines: external quality assessment and comparative testing for reference and in-clinic laboratories.

    Science.gov (United States)

    Camus, Melinda S; Flatland, Bente; Freeman, Kathleen P; Cruz Cardona, Janice A

    2015-12-01

    The purpose of this document is to educate providers of veterinary laboratory diagnostic testing in any setting about comparative testing. These guidelines will define, explain, and illustrate the importance of a multi-faceted laboratory quality management program which includes comparative testing. The guidelines will provide suggestions for implementation of such testing, including which samples should be tested, frequency of testing, and recommendations for result interpretation. Examples and a list of vendors and manufacturers supplying control materials and services to veterinary laboratories are also included. © 2015 American Society for Veterinary Clinical Pathology.

  15. Proficiency Test Program Involvement as a Tool for External Quality Control for Radiochemistry and Environmental Laboratory, Malaysian Nuclear Agency

    International Nuclear Information System (INIS)

    Nurrul Assyikeen Mohd Jaffary; Wo, Y.M.; Zal U'yun Wan Mahmood; Norfaizal Mohamed; Abdul Kadir Ishak; Noor Fadzilah Yusof; Jalal Sharib

    2016-01-01

    As the only Laboratory in Malaysia under the IAEA Analytical Laboratories for the Measurement of Environmental Radioactivity (ALMERA) Network, the Radiochemistry and Environmental Laboratory (RAS), Malaysian Nuclear Agency participates in the proficiency test programmes organised by ALMERA to achieve mutual acceptance of analytical data. The ALMERA has been providing quality support of proficiency tests using sets of different samples matrices and radionuclide levels typically encountered in environmental and food monitoring laboratories. The involvement of RAS laboratory in the IAEA proficiency tests gives opportunity to improve the laboratory capability and personnel skills in the field of radioactivity testing. (author)

  16. Laboratory rock mechanics testing manual. Public draft

    Energy Technology Data Exchange (ETDEWEB)

    Shuri, F S; Cooper, J D; Hamill, M L

    1981-10-01

    Standardized laboratory rock mechanics testing procedures have been prepared for use in the National Terminal Waste Storage Program. The procedures emphasize equipment performance specifications, documentation and reporting, and Quality Assurance acceptance criteria. Sufficient theoretical background is included to allow the user to perform the necessary data reduction. These procedures incorporate existing standards when possible, otherwise they represent the current state-of-the-art. Maximum flexibility in equipment design has been incorporated to allow use of this manual by existing groups and to encourage future improvements.

  17. High-dose secondary calibration laboratory accreditation program

    Energy Technology Data Exchange (ETDEWEB)

    Humphreys, J.C. [National Institute of Standards and Technology, Gaithersburg, MD (United States)

    1993-12-31

    There is a need for high-dose secondary calibration laboratories to serve the multi-billion dollar radiation processing industry. This need is driven by the desires of industry for less costly calibrations and faster calibration-cycle response time. Services needed include calibration irradiations of routine processing dosimeters and the supply of reference standard transfer dosimeters for irradiation in the production processing facility. In order to provide measurement quality assurance and to demonstrate consistency with national standards, the high-dose secondary laboratories would be accredited by means of an expansion of an existing National Voluntary Laboratory Accreditation Program. A laboratory performance criteria document is under development to implement the new program.

  18. High-dose secondary calibration laboratory accreditation program

    International Nuclear Information System (INIS)

    Humphreys, J.C.

    1993-01-01

    There is a need for high-dose secondary calibration laboratories to serve the multi-billion dollar radiation processing industry. This need is driven by the desires of industry for less costly calibrations and faster calibration-cycle response time. Services needed include calibration irradiations of routine processing dosimeters and the supply of reference standard transfer dosimeters for irradiation in the production processing facility. In order to provide measurement quality assurance and to demonstrate consistency with national standards, the high-dose secondary laboratories would be accredited by means of an expansion of an existing National Voluntary Laboratory Accreditation Program. A laboratory performance criteria document is under development to implement the new program

  19. Laboratory Directed Research and Development Program

    Energy Technology Data Exchange (ETDEWEB)

    Ogeka, G.J.

    1991-12-01

    Today, new ideas and opportunities, fostering the advancement of technology, are occurring at an ever-increasing rate. It, therefore, seems appropriate that a vehicle be available which fosters the development of these new ideas and technologies, promotes the early exploration and exploitation of creative and innovative concepts, and which develops new fundable'' R D projects and programs. At Brookhaven National Laboratory (BNL), one such method is through its Laboratory Directed Research and Development (LDRD) Program. This discretionary research and development tool is critical in maintaining the scientific excellence and vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community, fostering new science and technology ideas, which is the major factor achieving and maintaining staff excellence, and a means to address national needs, with the overall mission of the Department of Energy (DOE) and the Brookhaven National Laboratory. The Project Summaries with their accomplishments described in this report reflect the above. Aside from leading to new fundable or promising programs and producing especially noteworthy research, they have resulted in numerous publications in various professional and scientific journals, and presentations at meetings and forums.

  20. Creating Best Practices for the Submission of Actionable Food and Feed Testing Data Generated in State and Local Laboratories.

    Science.gov (United States)

    Wangsness, Kathryn; Salfinger, Yvonne; Randolph, Robyn; Shea, Shari; Larson, Kirsten

    2017-07-01

    Laboratory accreditation provides a level of standardization in laboratories and confidence in generated food and feed testing results. For some laboratories, ISO/IEC 17025:2005 accreditation may not be fiscally viable, or a requested test method may be out of the scope of the laboratory's accreditation. To assist laboratories for whom accreditation is not feasible, the Association of Public Health Laboratories Data Acceptance Work Group developed a white paper entitled "Best Practices for Submission of Actionable Food and Feed Testing Data Generated in State and Local Laboratories." The basic elements of a quality management system, along with other best practices that state and local food and feed testing laboratories should follow, are included in the white paper. It also covers program-specific requirements that may need to be addressed. Communication with programs and end data users is regarded as essential for establishing the reliability and accuracy of laboratory data. Following these suggested best practices can facilitate the acceptance of laboratory data, which can result in swift regulatory action and the quick removal of contaminated product from the food supply, improving public health nationally.

  1. The role of a certified calibration laboratory in a station's measuring and test equipment calibration, repair, and documentation program

    International Nuclear Information System (INIS)

    Ebenstreit, K.; MacIntosh, N.

    1995-01-01

    This paper outlines the role of a Certified Calibration Laboratory in- ensuring that the requirements of Measuring and Test Equipment calibration, identification, and traceability are met and documented. The Nuclear environment is one which is subject to influences from numerous 'quality agents'. One of the fields which comes under the scrutiny of the quality agents is that of equipment calibration and repair (both field components and M and TE). There is a responsibility to produce a superior product for the Ontario Consumer. The maintenance and calibration of Station Systems and their components have a direct impact on this output. The Measuring and Test Equipment element in each of these needs can be addressed by having a defined group of Maintenance Staff to execute a Measuring and Test Equipment Program which meets specific parameters. (author)

  2. Laboratory Directed Research ampersand Development Program

    International Nuclear Information System (INIS)

    Ogeka, G.J.; Romano, A.J.

    1993-12-01

    At Brookhaven National Laboratory the Laboratory Directed Research and Development (LDRD) Program is a discretionary research and development tool critical in maintaining the scientific excellence and vitality of the laboratory. It is also a means to stimulate the scientific community, fostering new science and technology ideas, which is the major factor in achieving and maintaining staff excellence, and a means to address national needs, within the overall mission of the Department of Energy and Brookhaven National Laboratory. This report summarizes research which was funded by this program during fiscal year 1993. The research fell in a number of broad technical and scientific categories: new directions for energy technologies; global change; radiation therapies and imaging; genetic studies; new directions for the development and utilization of BNL facilities; miscellaneous projects. Two million dollars in funding supported 28 projects which were spread throughout all BNL scientific departments

  3. Anthropomorphic Test Drive (ATD) Certification Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The ATD Certification Laboratory consists of several test fixtures to ensure ATDs are functioning correctly and within specifications prior to use in any OP testing....

  4. Argonne National Laboratory: Laboratory Directed Research and Development FY 1993 program activities. Annual report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1993-12-23

    The purposes of Argonne`s Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel concepts, enhance the Laboratory`s R&D capabilities, and further the development of its strategic initiatives. Projects are selected from proposals for creative and innovative R&D studies which are not yet eligible for timely support through normal programmatic channels. Among the aims of the projects supported by the Program are establishment of engineering ``proof-of-principle`` assessment of design feasibility for prospective facilities; development of an instrumental prototype, method, or system; or discovery in fundamental science. Several of these projects are closely associated with major strategic thrusts of the Laboratory as described in Argonne`s Five Year Institutional Plan, although the scientific implications of the achieved results extend well beyond Laboratory plans and objectives. The projects supported by the Program are distributed across the major programmatic areas at Argonne as indicated in the Laboratory LDRD Plan for FY 1993.

  5. Laboratory Directed Research and Development Program FY 2006 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Sjoreen, Terrence P [ORNL

    2007-04-01

    The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the US Departmental of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, 'Laboratory Directed Research and Development' (April 19, 2006), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries all ORNL LDRD research activities supported during FY 2006. The associated FY 2006 ORNL LDRD Self-Assessment (ORNL/PPA-2007/2) provides financial data about the FY 2006 projects and an internal evaluation of the program's management process.

  6. The NRU blowdown test facility commissioning program

    Energy Technology Data Exchange (ETDEWEB)

    Walsworth, J A; Zanatta, R J; Yamazaki, A R; Semeniuk, D D; Wong, W; Dickson, L W; Ferris, C E; Burton, D H [Atomic Energy of Canada Ltd., Chalk River, ON (Canada). Chalk River Nuclear Labs.

    1990-12-31

    A major experimental program has been established at the Chalk River Nuclear Laboratories (CRL) that will provide essential data on the thermal and mechanical behaviour of nuclear fuel under abnormal reactor operating conditions and on the transient release, transport and deposition of fission product activity from severely degraded fuel. A number of severe fuel damage (SFD) experiments will be conducted within the Blowdown Test Facility (BTF) at CRL. A series of experiments are being conducted to commission this new facility prior to the SFD program. This paper describes the features and the commissioning program for the BTF. A development and testing program is described for critical components used on the reactor test section. In-reactor commissioning with a fuel assembly simulator commenced in 1989 June and preliminary results are given. The paper also outlines plans for future all-effects, in-reactor tests of CANDU-designed fuel. (author). 11 refs., 3 tabs., 7 figs.

  7. Use of the National Committee for Clinical Laboratory Standards Guidelines for Disk Diffusion Susceptibility Testing in New York State Laboratories

    Science.gov (United States)

    Kiehlbauch, Julia A.; Hannett, George E.; Salfinger, Max; Archinal, Wendy; Monserrat, Catherine; Carlyn, Cynthia

    2000-01-01

    Accurate antimicrobial susceptibility testing is vital for patient care and surveillance of emerging antimicrobial resistance. The National Committee for Clinical Laboratory Standards (NCCLS) outlines generally agreed upon guidelines for reliable and reproducible results. In January 1997 we surveyed 320 laboratories participating in the New York State Clinical Evaluation Program for General Bacteriology proficiency testing. Our survey addressed compliance with NCCLS susceptibility testing guidelines for bacterial species designated a problem (Staphylococcus aureus and Enterococcus species) or fastidious (Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria gonorrhoeae) organism. Specifically, we assessed compliance with guidelines for inoculum preparation, medium choice, number of disks per plate, and incubation conditions for disk diffusion tests. We also included length of incubation for S. aureus and Enterococcus species. We found overall compliance with the five characteristics listed above in 80 of 153 responding laboratories (50.6%) for S. aureus and 72 of 151 (47.7%) laboratories for Enterococcus species. The most common problem was an incubation time shortened to less than 24 h. Overall compliance with the first four characteristics was reported by 92 of 221 (41.6%) laboratories for S. pneumoniae, 49 of 163 (30.1%) laboratories for H. influenzae, and 11 of 77 (14.3%) laboratories for N. gonorrhoeae. Laboratories varied from NCCLS guidelines by placing an excess number of disks per plate. Laboratories also reported using alternative media for Enterococcus species, N. gonorrhoeae, and H. influenzae. This study demonstrates a need for education among clinical laboratories to increase compliance with NCCLS guidelines. PMID:10970381

  8. Laboratory services series: a lubrication program

    Energy Technology Data Exchange (ETDEWEB)

    Bowen, H.B.; Miller, T.L.

    1976-05-01

    The diversity of equipment and operating conditions at a major national research and development laboratory requires a systematic, effective lubrication program. The various phases of this program and the techniques employed in formulating and administering this program are discussed under the following topics: Equipment Identification, Lubrication Requirements, Assortment of Lubricants, Personnel, and Scheduling.

  9. Laboratory services series: a lubrication program

    International Nuclear Information System (INIS)

    Bowen, H.B.; Miller, T.L.

    1976-05-01

    The diversity of equipment and operating conditions at a major national research and development laboratory requires a systematic, effective lubrication program. The various phases of this program and the techniques employed in formulating and administering this program are discussed under the following topics: Equipment Identification, Lubrication Requirements, Assortment of Lubricants, Personnel, and Scheduling

  10. Project Management Plan for the Idaho National Engineering Laboratory Waste Isolation Pilot Plant Experimental Test Program

    International Nuclear Information System (INIS)

    Connolly, M.J.; Sayer, D.L.

    1993-11-01

    EG ampersand G Idaho, Inc. and Argonne National Laboratory-West (ANL-W) are participating in the Idaho National Engineering Laboratory's (INEL's) Waste Isolation Pilot Plant (WIPP) Experimental Test Program (WETP). The purpose of the INEL WET is to provide chemical, physical, and radiochemical data on transuranic (TRU) waste to be stored at WIPP. The waste characterization data collected will be used to support the WIPP Performance Assessment (PA), development of the disposal No-Migration Variance Petition (NMVP), and to support the WIPP disposal decision. The PA is an analysis required by the Code of Federal Regulations (CFR), Title 40, Part 191 (40 CFR 191), which identifies the processes and events that may affect the disposal system (WIPP) and examines the effects of those processes and events on the performance of WIPP. A NMVP is required for the WIPP by 40 CFR 268 in order to dispose of land disposal restriction (LDR) mixed TRU waste in WIPP. It is anticipated that the detailed Resource Conservation and Recovery Act (RCRA) waste characterization data of all INEL retrievably-stored TRU waste to be stored in WIPP will be required for the NMVP. Waste characterization requirements for PA and RCRA may not necessarily be identical. Waste characterization requirements for the PA will be defined by Sandia National Laboratories. The requirements for RCRA are defined in 40 CFR 268, WIPP RCRA Part B Application Waste Analysis Plan (WAP), and WIPP Waste Characterization Program Plan (WWCP). This Project Management Plan (PMP) addresses only the characterization of the contact handled (CH) TRU waste at the INEL. This document will address all work in which EG ampersand G Idaho is responsible concerning the INEL WETP. Even though EG ampersand G Idaho has no responsibility for the work that ANL-W is performing, EG ampersand G Idaho will keep a current status and provide a project coordination effort with ANL-W to ensure that the INEL, as a whole, is effectively and

  11. Laboratory interface in support of Environmental Restoration Programs

    International Nuclear Information System (INIS)

    Pardue, G.J. Jr.

    1994-01-01

    A vital part of quality environmental data resides in the communication between the project and the analytical laboratory. It is essential that the project clearly identify its objectives to the laboratory and that the laboratory understands the scope and limitations of the analytical process. Successful completion of an environmental project must include an aggressive program between project managers and subcontracted Lyrical laboratories. All to often, individuals and organizations tend to deflect errors and failures observed in environmental toward open-quotes the other guyclose quotes. The engineering firm will blame the laboratory, the laboratory will blame the field operation, the field operation will blame the engineering, and everyone will blame the customer for not understanding the true variables in the environmental arena. It is the contention of the authors, that the majority of failures derive from a lack of communication and misunderstanding. Several initiatives can be taken to improve communication and understanding between the various pieces of the environmental data quality puzzle. This presentation attempts to outline mechanisms to improve communication between the environmental project and the analytical laboratory with the intent of continuous quality improvement. Concepts include: project specific laboratory statements of work which focus on project and program requirements; project specific analytical laboratory readiness reviews (project kick-off meetings); laboratory team workshops; project/program performance tracking and self assessment and promotion of team success

  12. Performance of IPEN/CNEN-SP Neutron Activation Analysis Laboratory for microelement determinations in proficiency testing

    International Nuclear Information System (INIS)

    Armelin, Maria Jose A.; Saiki, Mitiko; Souza, Gilberto B. de; Nogueira, Ana Rita A.

    2009-01-01

    The performance of Neutron Activation Laboratory, IPEN - CNEN/SP, was evaluated for the Ca, Fe, K, Mn, Na and Zn determinations in animal feed samples for ruminants through a proficiency test (PT) program. This PT program is organized by EMBRAPA Cattle Southeast to evaluate laboratories that analyze animal feed samples. Considering the fractions of satisfactory z-scores (%) of evaluated analytes to determine the laboratories performance, the general performance indicator obtained by IPEN - CNEN/SP ranged from 90 to 95% of the satisfactory results during the period of participation in the evaluation, four years. (author)

  13. PBF/LOFT Lead Rod Test Program experiment predictions document

    International Nuclear Information System (INIS)

    Varacalle, D.J.; Cox, W.R.; Niebruegge, D.A.; Seiber, S.J.; Brake, T.E.; Driskell, W.E.; Nigg, D.W.; Tolman, E.L.

    1978-12-01

    The PBF/LOFT Lead Rod (LLR) Test Program is being conducted to provide experimental information on the behavior of nuclear fuel under normal and accident conditions in the Power Burst Facility (PBF) at the Idaho National Engineering Laboratory. The PBF/LLR tests are designed to simulate the test conditions for the LOFT Power Ascension Tests L2-3 through L2-5. The test program has been designed to provide a parametric evaluation of the LOFT fuel (center and peripheral modules) over a wide range of power. This report presents the experiment predictions for the three four-rod LOCA tests

  14. The Rwanda Field Epidemiology and Laboratory Training Program ...

    African Journals Online (AJOL)

    The Rwanda Field Epidemiology and Laboratory Training Program (RFELTP) is a 2-year public health leadership development training program that provides applied epidemiology and public health laboratory training while the trainees provide public health service to the Ministry of Health. RFELTP is hosted at the National ...

  15. Electromedical devices test laboratories accreditation

    International Nuclear Information System (INIS)

    Murad, C; Rubio, D; Ponce, S; Alvarez Abri, A; Terron, A; Vicencio, D; Fascioli, E

    2007-01-01

    In the last years, the technology and equipment at hospitals have been increase in a great way as the risks of their implementation. Safety in medical equipment must be considered an important issue to protect patients and their users. For this reason, test and calibrations laboratories must verify the correct performance of this kind of devices under national and international standards. Is an essential mission for laboratories to develop their measurement activities taking into account a quality management system. In this article, we intend to transmit our experience working to achieve an accredited Test Laboratories for medical devices in National technological University

  16. The quality of veterinary in-clinic and reference laboratory biochemical testing.

    Science.gov (United States)

    Rishniw, Mark; Pion, Paul D; Maher, Tammy

    2012-03-01

    Although evaluation of biochemical analytes in blood is common in veterinary practice, studies assessing the global quality of veterinary in-clinic and reference laboratory testing have not been reported. The aim of this study was to assess the quality of biochemical testing in veterinary laboratories using results obtained from analyses of 3 levels of assayed quality control materials over 5 days. Quality was assessed by comparison of calculated total error with quality requirements, determination of sigma metrics, use of a quality goal index to determine factors contributing to poor performance, and agreement between in-clinic and reference laboratory mean results. The suitability of in-clinic and reference laboratory instruments for statistical quality control was determined using adaptations from the computerized program, EZRules3. Reference laboratories were able to achieve desirable quality requirements more frequently than in-clinic laboratories. Across all 3 materials, > 50% of in-clinic analyzers achieved a sigma metric ≥ 6.0 for measurement of 2 analytes, whereas > 50% of reference laboratory analyzers achieved a sigma metric ≥ 6.0 for measurement of 6 analytes. Expanded uncertainty of measurement and ± total allowable error resulted in the highest mean percentages of analytes demonstrating agreement between in-clinic and reference laboratories. Owing to marked variation in bias and coefficient of variation between analyzers of the same and different types, the percentages of analytes suitable for statistical quality control varied widely. These findings reflect the current state-of-the-art with regard to in-clinic and reference laboratory analyzer performance and provide a baseline for future evaluations of the quality of veterinary laboratory testing. © 2012 American Society for Veterinary Clinical Pathology.

  17. High Performance Computing Modernization Program Kerberos Throughput Test Report

    Science.gov (United States)

    2017-10-26

    Naval Research Laboratory Washington, DC 20375-5320 NRL/MR/5524--17-9751 High Performance Computing Modernization Program Kerberos Throughput Test ...NUMBER 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 2. REPORT TYPE1. REPORT DATE (DD-MM-YYYY) 4. TITLE AND SUBTITLE 6. AUTHOR(S) 8. PERFORMING...PAGE 18. NUMBER OF PAGES 17. LIMITATION OF ABSTRACT High Performance Computing Modernization Program Kerberos Throughput Test Report Daniel G. Gdula* and

  18. [How do hospital clinical laboratories and laboratory testing companies cooperate and build reciprocal relations?].

    Science.gov (United States)

    Kawano, Seiji

    2014-12-01

    As the 2nd Joint Symposium of the Japanese Society of Laboratory Medicine and the Japanese Association of Laboratory Pathologists, the symposium on clinical test out-sourcing and branch laboratories was held at the 60th General Meeting of the Japanese Society of Laboratory Medicine on November 2nd, 2013 in Kobe. For the symposium, we conducted a questionnaire survey on the usage of clinical test out-sourcing and the introduction of branch laboratories to clinical laboratories of Japanese university hospitals, both private and public, between July 25th and August 20th, 2013. Seventy-two hospitals responded to the questionnaire survey, consisting of 41 public medical school hospitals and 31 private ones. According to the survey, the selection of each clinical test for out-sourcing was mainly determined by the capacities of hospital clinical laboratories and their equipment, as well as the profitability of each test. The main concerns of clinical laboratory members of university hospitals involved the continuity of measurement principles, traceability, and standardization of reference values for each test. They strongly requested the interchangeability and computerization of test data between laboratory testing companies. A branch laboratory was introduced to six hospitals, all of which were private medical college hospitals, out of 72 university hospitals, and eight of the other hospitals were open to its introduction. The merits and demerits of introducing a branch laboratory were also discussed. (Review).

  19. Research and Development Program for transportation packagings at Sandia National Laboratories

    International Nuclear Information System (INIS)

    Hohnstreiter, G.F.; Sorenson, K.B.

    1995-01-01

    This document contains information about the research and development programs dealing with waste transport at Sandia National Laboratories. This paper discusses topics such as: Why new packaging is needed; analytical methodologies and design codes;evaluation of packaging components; materials characterization; creative packaging concepts; packaging engineering and analysis; testing; and certification support

  20. Review of laboratory programs for women Points-of-Contact Committee

    Energy Technology Data Exchange (ETDEWEB)

    Duke, D.; Magrini, K. [comps.] [National Renewable Energy Lab., Golden, CO (United States); McLane, V. [comp.] [Brookhaven National Lab., Upton, NY (United States); Wieda, K. [comp.] [Pacific Northwest Lab., Richland, WA (United States)

    1995-06-01

    The mission of the DOE Review of Laboratory Programs for Women is to: provide DOE and its Laboratories with effective strategies, targeting women, for establishing aggressive outreach programs which improve the access of women to careers in science, engineering, and mathematics. Ensure that the Department and its Laboratories are exemplary places of employment by providing programs which enhance opportunity, remove barriers, and assist women in achieving full professional development. A survey of the DOE facilities was undertaken by the Points-of-Contact for the DOE Review of Laboratory Programs for Women in order to gather data to be used as a baseline against which to measure future progress. We plan to look at current programs already in place and evaluate them with a view to deciding which programs are most effective, and selecting model programs suitable for implementation at other facilities. The survey focused on four areas: statistical data, laboratory policy, formal and informal programs which affect the quality of life in the work environment, and career development and advancement, and educational programs. Although this report focuses on women, the problems discussed affect all DOE facility employees.

  1. US Department of Energy Laboratory Accreditation Program for personnel dosimetry systems (DOELAP)

    International Nuclear Information System (INIS)

    Carlson, R.D.; Gesell, T.F.; Kalbeitzer, F.L.; Roberson, P.L.; Jones, K.L.; MacDonald, J.C.; Vallario, E.J.; Pacific Northwest Lab., Richland, WA; USDOE Assistant Secretary for Nuclear Energy, Washington, DC

    1988-01-01

    The US Department of Energy (DOE) Office of Nuclear Safety has developed and initiated the DOE Laboratory Accreditation Program (DOELAP) for personnel dosimetry systems to assure and improve the quality of personnel dosimetry at DOE and DOE contractor facilities. It consists of a performance evaluation program that measures current performance and an applied research program that evaluates and recommends additional or improved test and performance criteria. It also provides guidance to DOE, identifying areas where technological improvements are needed. The two performance evaluation elements in the accreditation process are performance testing and onsite assessment by technical experts. Performance testing evaluates the participant's ability to accurately and reproducibly measure dose equivalent. Tests are conducted in accident level categories for low- and high-energy photons as well as protection level categories for low- and high-energy photons, beta particles, neutrons and mixtures of these

  2. Dose calculation algorithm for the Department of Energy Laboratory Accreditation Program

    International Nuclear Information System (INIS)

    Moscovitch, M.; Tawil, R.A.; Thompson, D.; Rhea, T.A.

    1991-01-01

    The dose calculation algorithm for a symmetric four-element LiF:Mg,Ti based thermoluminescent dosimeter is presented. The algorithm is based on the parameterization of the response of the dosimeter when exposed to both pure and mixed fields of various types and compositions. The experimental results were then used to develop the algorithm as a series of empirical response functions. Experiments to determine the response of the dosimeter and to test the dose calculation algorithm were performed according to the standard established by the Department of Energy Laboratory Accreditation Program (DOELAP). The test radiation fields include: 137 Cs gamma rays, 90 Sr/ 90 Y and 204 Tl beta particles, low energy photons of 20-120 keV and moderated 252 Cf neutron fields. The accuracy of the system has been demonstrated in an official DOELAP blind test conducted at Sandia National Laboratory. The test results were well within DOELAP tolerance limits. The results of this test are presented and discussed

  3. Laboratory Directed Research and Development Program FY 2007 Annual Report

    International Nuclear Information System (INIS)

    Sjoreen, Terrence P.

    2008-01-01

    The Oak Ridge National LaboratoryLaboratory Directed Research and Development (LDRD) program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, 'Laboratory Directed Research and Development' (April 19, 2006), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries for all ORNL LDRD research activities supported during FY 2007. The associated FY 2007 ORNL LDRD Self-Assessment (ORNL/PPA-2008/2) provides financial data and an internal evaluation of the program's management process. ORNL is a DOE multiprogram science, technology, and energy laboratory with distinctive capabilities in materials science and engineering, neutron science and technology, energy production and end-use technologies, biological and environmental science, and scientific computing. With these capabilities ORNL conducts basic and applied research and development (R and D) to support DOE's overarching mission to advance the national, economic, and energy security of the United States and promote scientific and technological innovation in support of that mission. As a national resource, the Laboratory also applies its capabilities and skills to specific needs of other federal agencies and customers through the DOE Work for Others (WFO) program. Information about the Laboratory and its programs is available on the Internet at http://www.ornl.gov/. LDRD is a relatively small but vital DOE program that allows ORNL, as well as other DOE laboratories, to select a limited number of R and D projects for the purpose of: (1) maintaining the scientific and technical vitality of the Laboratory; (2) enhancing the Laboratory's ability to address future DOE missions; (3) fostering creativity and stimulating exploration of forefront science

  4. Laboratory Directed Research and Development Program FY 2007 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Sjoreen, Terrence P [ORNL

    2008-04-01

    The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, 'Laboratory Directed Research and Development' (April 19, 2006), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries for all ORNL LDRD research activities supported during FY 2007. The associated FY 2007 ORNL LDRD Self-Assessment (ORNL/PPA-2008/2) provides financial data and an internal evaluation of the program's management process. ORNL is a DOE multiprogram science, technology, and energy laboratory with distinctive capabilities in materials science and engineering, neutron science and technology, energy production and end-use technologies, biological and environmental science, and scientific computing. With these capabilities ORNL conducts basic and applied research and development (R&D) to support DOE's overarching mission to advance the national, economic, and energy security of the United States and promote scientific and technological innovation in support of that mission. As a national resource, the Laboratory also applies its capabilities and skills to specific needs of other federal agencies and customers through the DOE Work for Others (WFO) program. Information about the Laboratory and its programs is available on the Internet at http://www.ornl.gov/. LDRD is a relatively small but vital DOE program that allows ORNL, as well as other DOE laboratories, to select a limited number of R&D projects for the purpose of: (1) maintaining the scientific and technical vitality of the Laboratory; (2) enhancing the Laboratory's ability to address future DOE missions; (3) fostering creativity and stimulating

  5. Laboratory for filter testing

    Energy Technology Data Exchange (ETDEWEB)

    Paluch, W.

    1987-07-01

    Filters used for mine draining in brown coal surface mines are tested by the Mine Draining Department of Poltegor. Laboratory tests of new types of filters developed by Poltegor are analyzed. Two types of tests are used: tests of scale filter models and tests of experimental units of new filters. Design and operation of the test stands used for testing mechanical properties and hydraulic properties of filters for coal mines are described: dimensions, pressure fluctuations, hydraulic equipment. Examples of testing large-diameter filters for brown coal mines are discussed.

  6. Laboratory Testing of Waste Isolation Pilot Plant Surrogate Waste Materials

    Science.gov (United States)

    Broome, S.; Bronowski, D.; Pfeifle, T.; Herrick, C. G.

    2011-12-01

    The Waste Isolation Pilot Plant (WIPP) is a U.S. Department of Energy geological repository for the permanent disposal of defense-related transuranic (TRU) waste. The waste is emplaced in rooms excavated in the bedded Salado salt formation at a depth of 655 m below the ground surface. After emplacement of the waste, the repository will be sealed and decommissioned. WIPP Performance Assessment modeling of the underground material response requires a full and accurate understanding of coupled mechanical, hydrological, and geochemical processes and how they evolve with time. This study was part of a broader test program focused on room closure, specifically the compaction behavior of waste and the constitutive relations to model this behavior. The goal of this study was to develop an improved waste constitutive model. The model parameters are developed based on a well designed set of test data. The constitutive model will then be used to realistically model evolution of the underground and to better understand the impacts on repository performance. The present study results are focused on laboratory testing of surrogate waste materials. The surrogate wastes correspond to a conservative estimate of the degraded containers and TRU waste materials after the 10,000 year regulatory period. Testing consists of hydrostatic, uniaxial, and triaxial tests performed on surrogate waste recipes that were previously developed by Hansen et al. (1997). These recipes can be divided into materials that simulate 50% and 100% degraded waste by weight. The percent degradation indicates the anticipated amount of iron corrosion, as well as the decomposition of cellulosics, plastics, and rubbers. Axial, lateral, and volumetric strain and axial and lateral stress measurements were made. Two unique testing techniques were developed during the course of the experimental program. The first involves the use of dilatometry to measure sample volumetric strain under a hydrostatic condition. Bulk

  7. Recommended well drilling and testing program

    International Nuclear Information System (INIS)

    Long, J.; Wilson, C.

    1978-07-01

    A well drilling and testing program is recommended by Lawrence Berkeley Laboratory to identify the hydrology of deep basalts in the Pasco Basin. The ultimate objective of this program is to assist in determining the feasibility of locating a nuclear waste repository on the Hanford Reservation. The recommended program has been staged for maximum effectiveness. In the first stage, six wells have been identified for drilling and testing which, when coupled with existing wells, will provide sufficient data for a preliminary overview of basin hydrology and a preliminary determination of the hydrologic suitability of the deep basalt for a repository site. The rate at which the first stage wells are drilled and tested will depend upon the date at which a preliminary determination of site suitability is required. It was assumed that a preliminary determination of suitability would be required in 1980, in which case all six first stage wells would be drilled in FY 1979. If the results of the first stage analysis are favorable for repository siting, tentative repository sites can be identified and a second stage hydrology program can be implemented to provide the necessary details of the flow system. To accomplish this stage, a number of deep wells would be required at locations both inside and outside the basin, with specific sites to be identified as the work progresses to obtain maximum utility of existing data. A program is recommended for testing in each new well and for completion of testing in each existing well. Recommended tests include borehole geophysics, pressure and permeability testing, geochemical sampling, tracer testing, hydrofracturing and borehole fracture logging. The entire data collection program is oriented toward providing the information required to establish and verify an accurate numerical model of the Pasco Basin

  8. Laboratory Directed Research and Development Program FY98

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, T. [ed.; Chartock, M.

    1999-02-05

    The Ernest Orlando Lawrence Berkeley National Laboratory (LBNL or Berkeley Lab) Laboratory Directed Research and Development Program FY 1998 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the supported projects and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development (LDRD) program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The LBNL LDRD program is a critical tool for directing the Laboratory's forefront scientific research capabilities toward vital, excellent, and emerging scientific challenges. The program provides the resources for LBNL scientists to make rapid and significant contributions to critical national science and technology problems. The LDRD program also advances LBNL's core competencies, foundations, and scientific capability, and permits exploration of exciting new opportunities. All projects are work in forefront areas of science and technology. Areas eligible for support include the following: Advanced study of hypotheses, concepts, or innovative approaches to scientific or technical problems; Experiments and analyses directed toward ''proof of principle'' or early determination of the utility of new scientific ideas, technical concepts, or devices; and Conception and preliminary technical analyses of experimental facilities or devices.

  9. ORNLs Laboratory Directed Research and Development Program FY 2010 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2011-03-01

    The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2010. The associated FY 2010 ORNL LDRD Self-Assessment (ORNL/PPA-2011/2) provides financial data and an internal evaluation of the program’s management process.

  10. ORNLs Laboratory Directed Research and Development Program FY 2009 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2010-03-01

    The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries all ORNL LDRD research activities supported during FY 2009. The associated FY 2009 ORNL LDRD Self-Assessment (ORNL/PPA-2010/2) provides financial data and an internal evaluation of the program’s management process.

  11. ORNLs Laboratory Directed Research and Development Program FY 2008 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2009-03-01

    The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries all ORNL LDRD research activities supported during FY 2008. The associated FY 2008 ORNL LDRD Self-Assessment (ORNL/PPA-2008/2) provides financial data and an internal evaluation of the program’s management process.

  12. ORNLs Laboratory Directed Research and Development Program FY 2013 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2014-03-01

    The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the US Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2013. The associated FY 2013 ORNL LDRD Self-Assessment (ORNL/PPA-2014/2) provides financial data and an internal evaluation of the program’s management process.

  13. ORNLs Laboratory Directed Research and Development Program FY 2012 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2013-03-01

    The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the US Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2012. The associated FY 2012 ORNL LDRD Self-Assessment (ORNL/PPA-2012/2) provides financial data and an internal evaluation of the program’s management process.

  14. ORNLs Laboratory Directed Research and Development Program FY 2011 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2012-03-01

    The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2011. The associated FY 2011 ORNL LDRD Self-Assessment (ORNL/PPA-2012/2) provides financial data and an internal evaluation of the program’s management process.

  15. Good laboratory practices for biochemical genetic testing and newborn screening for inherited metabolic disorders.

    Science.gov (United States)

    2012-04-06

    Biochemical genetic testing and newborn screening are essential laboratory services for the screening, detection, diagnosis, and monitoring of inborn errors of metabolism or inherited metabolic disorders. Under the Clinical Laboratory Improvement Amendments of 1988 (CLIA) regulations, laboratory testing is categorized on the basis of the level of testing complexity as either waived (i.e., from routine regulatory oversight) or nonwaived testing (which includes tests of moderate and high complexity). Laboratories that perform biochemical genetic testing are required by CLIA regulations to meet the general quality systems requirements for nonwaived testing and the personnel requirements for high-complexity testing. Laboratories that perform public health newborn screening are subject to the same CLIA regulations and applicable state requirements. As the number of inherited metabolic diseases that are included in state-based newborn screening programs continues to increase, ensuring the quality of performance and delivery of testing services remains a continuous challenge not only for public health laboratories and other newborn screening facilities but also for biochemical genetic testing laboratories. To help ensure the quality of laboratory testing, CDC collaborated with the Centers for Medicare & Medicaid Services, the Food and Drug Administration, the Health Resources and Services Administration, and the National Institutes of Health to develop guidelines for laboratories to meet CLIA requirements and apply additional quality assurance measures for these areas of genetic testing. This report provides recommendations for good laboratory practices that were developed based on recommendations from the Clinical Laboratory Improvement Advisory Committee, with additional input from the Secretary's Advisory Committee on Genetics, Health, and Society; the Secretary's Advisory Committee on Heritable Disorders in Newborns and Children; and representatives of newborn

  16. Laboratory testing of LITCO glasses

    International Nuclear Information System (INIS)

    Ellison, A.; Wolf, S.; Buck, E.; Luo, J.S.; Dietz, N.; Bates, J.K.; Ebert, W.L.

    1995-01-01

    The purpose of this program is to measure, the intermediate and long-term durability of glasses developed by Lockheed Idaho Technology Co. (LITCO) for the immobilization of calcined radioactive wastes. The objective is to use accelerated corrosion tests as an aid in developing durable waste form compositions. This is a report of tests performed on two LITCO glass compositions, Formula 127 and Formula 532. The main avenue for release of radionuclides into the environment in a geologic repository is the reaction of a waste glass with ground water, which alters the glass and releases its components into solution. These stages in glass corrosion are analyzed by using accelerated laboratory tests in which the ratio of sample surface area to solution volume, SA/V, is varied. At low SA/V, the solution concentrations of glass corrosion products remain low and the reaction approaches the forward rate. At higher SA/V the solution approaches saturation levels for glass corrosion products. At very high SA/V the solution is rapidly saturated in glass corrosion products and secondary crystalline phases precipitate. Tests at very high SA/V provide information about the composition of the solution at saturation or, when no solution is recovered, the identities and the order of appearance of secondary crystalline phases. Tests were applied to Formula 127 and Formula 532 glasses to provide information about the interim and long-term stages in glass corrosion

  17. FTIR Laboratory in Support of the PV Program

    International Nuclear Information System (INIS)

    Keyes, B. M.; Gedvilas, L. M.; Bhattacharya, R.; Xu, Y.; Li, X.; Wang, Q.

    2005-01-01

    The Fourier Transform Infrared Spectroscopy (FTIR) Laboratory supports the Solar Energy Technologies Program through the measurement and characterization of solar energy-related materials and devices. The FTIR technique is a fast, accurate, and reliable method for studying molecular structure and composition. This ability to identify atomic species and their bonding environment is a powerful combination that finds use in many research and development efforts. A brief overview of the technical approach used is contained in Section 2 of this report. Because of its versatility and accessibility, the FTIR Laboratory is a valuable contributor to the Solar Energy Technologies Program. The laboratory provides support for, and collaborates with, several in-house programs as well as our industry and university partners. By the end of FY 2004, the FTIR Laboratory performed over 1100 measurements on PV-related materials. These contributions resulted in conference and workshop presentations and several peer-reviewed publications. A brief summary of a few of these efforts is contained in Section 3 of this report

  18. Math and science education programs from the Idaho National Engineering Laboratory

    International Nuclear Information System (INIS)

    1991-01-01

    This booklet reviews math and science education programs at the Idaho National Engineering Laboratory (INEL). The programs can be categorized into six groups: teacher programs; science laboratories for students; student programs; education outreach programs; INEL Public Affairs Office; and programs for college faculty and students

  19. Laboratory Directed Research and Development Program FY 2005 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Sjoreen, Terrence P [ORNL

    2006-04-01

    The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2A, 'Laboratory Directed Research and Development' (January 8, 2001), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report describes all ORNL LDRD research activities supported during FY 2005 and includes final reports for completed projects and shorter progress reports for projects that were active, but not completed, during this period. The FY 2005 ORNL LDRD Self-Assessment (ORNL/PPA-2006/2) provides financial data about the FY 2005 projects and an internal evaluation of the program's management process. ORNL is a DOE multiprogram science, technology, and energy laboratory with distinctive capabilities in materials science and engineering, neutron science and technology, energy production and end-use technologies, biological and environmental science, and scientific computing. With these capabilities ORNL conducts basic and applied research and development (R&D) to support DOE's overarching national security mission, which encompasses science, energy resources, environmental quality, and national nuclear security. As a national resource, the Laboratory also applies its capabilities and skills to the specific needs of other federal agencies and customers through the DOE Work For Others (WFO) program. Information about the Laboratory and its programs is available on the Internet at . LDRD is a relatively small but vital DOE program that allows ORNL, as well as other multiprogram DOE laboratories, to select a limited number of R&D projects for the purpose of: (1) maintaining the scientific and technical vitality of the

  20. Laboratory Directed Research and Development Program FY 2004 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Sjoreen, Terrence P [ORNL

    2005-04-01

    The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2A, 'Laboratory Directed Research and Development' (January 8, 2001), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report describes all ORNL LDRD research activities supported during FY 2004 and includes final reports for completed projects and shorter progress reports for projects that were active, but not completed, during this period. The FY 2004 ORNL LDRD Self-Assessment (ORNL/PPA-2005/2) provides financial data about the FY 2004 projects and an internal evaluation of the program's management process. ORNL is a DOE multiprogram science, technology, and energy laboratory with distinctive capabilities in materials science and engineering, neutron science and technology, energy production and end-use technologies, biological and environmental science, and scientific computing. With these capabilities ORNL conducts basic and applied research and development (R&D) to support DOE's overarching national security mission, which encompasses science, energy resources, environmental quality, and national nuclear security. As a national resource, the Laboratory also applies its capabilities and skills to the specific needs of other federal agencies and customers through the DOE Work For Others (WFO) program. Information about the Laboratory and its programs is available on the Internet at . LDRD is a relatively small but vital DOE program that allows ORNL, as well as other multiprogram DOE laboratories, to select a limited number of R&D projects for the purpose of: (1) maintaining the scientific and technical vitality of the

  1. ISO 15189 accreditation: Requirements for quality and competence of medical laboratories, experience of a laboratory I.

    Science.gov (United States)

    Guzel, Omer; Guner, Ebru Ilhan

    2009-03-01

    Medical laboratories are the key partners in patient safety. Laboratory results influence 70% of medical diagnoses. Quality of laboratory service is the major factor which directly affects the quality of health care. The clinical laboratory as a whole has to provide the best patient care promoting excellence. International Standard ISO 15189, based upon ISO 17025 and ISO 9001 standards, provides requirements for competence and quality of medical laboratories. Accredited medical laboratories enhance credibility and competency of their testing services. Our group of laboratories, one of the leading institutions in the area, had previous experience with ISO 9001 and ISO 17025 Accreditation at non-medical sections. We started to prepared for ISO 15189 Accreditation at the beginning of 2006 and were certified in March, 2007. We spent more than a year to prepare for accreditation. Accreditation scopes of our laboratory were as follows: clinical chemistry, hematology, immunology, allergology, microbiology, parasitology, molecular biology of infection serology and transfusion medicine. The total number of accredited tests is 531. We participate in five different PT programs. Inter Laboratory Comparison (ILC) protocols are performed with reputable laboratories. 82 different PT Program modules, 277 cycles per year for 451 tests and 72 ILC program organizations for remaining tests have been performed. Our laboratory also organizes a PT program for flow cytometry. 22 laboratories participate in this program, 2 cycles per year. Our laboratory has had its own custom made WEB based LIS system since 2001. We serve more than 500 customers on a real time basis. Our quality management system is also documented and processed electronically, Document Management System (DMS), via our intranet. Preparatory phase for accreditation, data management, external quality control programs, personnel related issues before, during and after accreditation process are presented. Every laboratory has

  2. The advanced controls program at Oak Ridge National Laboratory

    International Nuclear Information System (INIS)

    Knee, H.E.; White, J.D.

    1990-01-01

    The Oak Ridge National Laboratory (ORNL), under sponsorship of the US Department of Energy (DOE), is conducting research that will lead to advanced, automated control of new liquid-metal-reactor (LMR) nuclear power plants. Although this program of research (entitled the ''Advanced Controls Program'') is focused on LMR technology, it will be capable of providing control design, test, and qualification capability for other advanced reactor designs (e.g., the advanced light water reactor [ALWR] and high temperature gas-cooled reactor [HTGR] designs), while also benefiting existing nuclear plants. The Program will also have applicability to complex, non-nuclear process control environments (e.g., petrochemical, aerospace, etc.). The Advanced Controls Program will support capabilities throughout the entire plant design life cycle, i.e., from the initial interactive first-principle dynamic model development for the process, systems, components, and instruments through advanced control room qualification. The current program involves five principal areas of research activities: (1) demonstrations of advanced control system designs, (2) development of an advanced controls design environment, (3) development of advanced control strategies, (4) research and development (R ampersand D) in human-system integration for advanced control system designs, and (5) testing and validation of advanced control system designs. Discussion of the research in these five areas forms the basis of this paper. Also included is a description of the research directions of the program. 8 refs

  3. Photovoltaic module certification/laboratory accreditation criteria development

    Energy Technology Data Exchange (ETDEWEB)

    Osterwald, C.R. [National Renewable Energy Lab., Golden, CO (United States); Hammond, R.L.; Wood, B.D.; Backus, C.E.; Sears, R.L. [Arizona State Univ., Tempe, AZ (United States); Zerlaut, G.A. [SC-International Inc., Phoenix, AZ (United States); D`Aiello, R.V. [RD Associates, Tempe, AZ (United States)

    1995-04-01

    This document provides an overview of the structure and function of typical product certification/laboratory accreditation programs. The overview is followed by a model program which could serve as the basis for a photovoltaic (PV) module certification/laboratory accreditation program. The model covers quality assurance procedures for the testing laboratory and manufacturer, third-party certification and labeling, and testing requirements (performance and reliability). A 30-member Criteria Development Committee was established to guide, review, and reach a majority consensus regarding criteria for a PV certification/laboratory accreditation program. Committee members represented PV manufacturers, end users, standards and codes organizations, and testing laboratories.

  4. [Quality use of commercial laboratory for clinical testing services - considering laboratory's role].

    Science.gov (United States)

    Ogawa, Shinji

    2014-12-01

    The number of commercial laboratories for clinical testing in Japan run privately has decreased to about 30 companies, and their business is getting tougher. Branch Lab. and FMS businesses have not expanded recently due to the new reimbursement system which adds an additional sample management fee, becoming effective in 2010. This presentation gives an outline of each role for hospital and commercial laboratories, and their pros & cons considering the current medical situation. Commercial laboratories have investigated how to utilize ICT systems for sharing test information between hospitals and our facilities. It would be very helpful to clarify issues for each hospital. We will develop and create new values for clinical laboratory testing services and forge mutually beneficial relationships with medical institutions. (Review).

  5. Collaborative Testing in Practical Laboratories: An Effective Teaching-Learning Method in Histology.

    Science.gov (United States)

    Guo, Yuping; Li, Enzhong

    2016-01-01

    This article presents an experimental teaching and learning program used in histology with first-year students in the second term in the Faculty of Biology at Huanghuai University, China. Eighty-six students were divided randomly into two groups (n=43 per group). Tests were conducted at the end of each practical laboratory (10 laboratories in total) in which collaborative testing was used in the experimental group and traditional testing in the control group. To assess achievement, a final examination in histology was carried out at the end of the course. To determine students' attitude to the teaching styles, a questionnaire survey was conducted at the end of the term. Results showed that students preferred the collaborative testing format. In the experimental group, students' scores were significantly higher than those of students in the control group in final examinations. These findings indicate that collaborative testing enhances student learning and understanding of the material taught, and suggest that collaborative testing is an effective teaching-learning method in histology.

  6. HVPTF-The high voltage laboratory for the ITER Neutral Beam test facility

    Energy Technology Data Exchange (ETDEWEB)

    De Lorenzi, A., E-mail: antonio.delorenzi@igi.cnr.it [Consorzio RFX-Associazione EURATOM-ENEA per la Fusione Corso Stati Uniti 4, 35127 Padova (Italy); Pilan, N.; Lotto, L.; Fincato, M. [Consorzio RFX-Associazione EURATOM-ENEA per la Fusione Corso Stati Uniti 4, 35127 Padova (Italy); Pesavento, G.; Gobbo, R. [DIE, Universita di Padova, Via Gradenigo 6A, I-35100 Padova (Italy)

    2011-10-15

    In the MITICA research program for the construction of the ITER Neutral Beam Injector prototype, a Laboratory for the investigation on high voltage holding in vacuum has been set up. This Laboratory - HVPTF: High Voltage Padova Test Facility - is presently capable of experiments up to 300 kV dc, and planned for the upgrade to 800 kV. The specific mission for this ancillary lab is the support to the electrostatic design and construction of the MITICA accelerator and the development and testing of HV components to be installed inside the MITICA accelerator during its operation. The paper describes the structure of the lab, characterized by a high degree of automation and reports the results of the commissioning at 300 kV and the first results of voltage holding between test electrodes.

  7. HVPTF-The high voltage laboratory for the ITER Neutral Beam test facility

    International Nuclear Information System (INIS)

    De Lorenzi, A.; Pilan, N.; Lotto, L.; Fincato, M.; Pesavento, G.; Gobbo, R.

    2011-01-01

    In the MITICA research program for the construction of the ITER Neutral Beam Injector prototype, a Laboratory for the investigation on high voltage holding in vacuum has been set up. This Laboratory - HVPTF: High Voltage Padova Test Facility - is presently capable of experiments up to 300 kV dc, and planned for the upgrade to 800 kV. The specific mission for this ancillary lab is the support to the electrostatic design and construction of the MITICA accelerator and the development and testing of HV components to be installed inside the MITICA accelerator during its operation. The paper describes the structure of the lab, characterized by a high degree of automation and reports the results of the commissioning at 300 kV and the first results of voltage holding between test electrodes.

  8. LABORATORY DIRECTED RESEARCH AND DEVELOPMENT PROGRAM ASSESSMENT FOR FY 2006.

    Energy Technology Data Exchange (ETDEWEB)

    FOX,K.J.

    2006-01-01

    Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's total annual budget has averaged about $460 million. There are about 2,500 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 413.2B, ''Laboratory Directed Research and Development,'' April 19,2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy National Nuclear Security Administration Laboratories dated June 13,2006. The goals and' objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new ''fundable'' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research ''which could lead to new programs, projects, and directions'' for the Laboratory. As one of the premier scientific laboratories of the DOE, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its LDRD Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community and foster new

  9. Laboratory Directed Research and Development Program Assessment for FY 2007

    Energy Technology Data Exchange (ETDEWEB)

    Newman,L.; Fox, K.J.

    2007-12-31

    Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal Year 2007 spending was $515 million. There are approximately 2,600 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development', April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new 'fundable' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research 'which could lead to new programs, projects, and directions' for the Laboratory. As one of the premier scientific laboratories of the DOE, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its LDRD Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community and foster new science and technology ideas, which

  10. LWR aerosol containment experiments (LACE) program and initial test results

    International Nuclear Information System (INIS)

    Muhlestein, L.D.; Hilliard, R.K.; Bloom, G.R.; McCormack, J.D.; Rahn, F.J.

    1985-01-01

    The LWR aerosol containment experiments (LACE) program is described. The LACE program is being performed at the Hanford Engineer Development Laboratory (operated by Westinghouse Hanford Company) and the initial tests are sponsored by EPRI. The objectives of the LACE program are: to demonstrate, at large-scale, inherent radioactive aerosol retention behavior for postulated high consequence LWR accident situations; and to provide a data base to be used for aerosol behavior . Test results from the first phase of the LACE program are presented and discussed. Three large-scale scoping tests, simulating a containment bypass accident sequence, demonstrated the extent of agglomeration and deposition of aerosols occurring in the pipe pathway and vented auxiliary building under realistic accident conditions. Parameters varied during the scoping tests were aerosol type and steam condensation

  11. Development of a quality assurance program for ionizing radiation secondary calibration laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Heaton, H.T. II; Taylor, A.R. Jr. [Center for Devices and Radiological Health, Rockville, MD (United States)

    1993-12-31

    For calibration laboratories, routine calibrations of instruments meeting stated accuracy goals are important. One method of achieving the accuracy goals is to establish and follow a quality assurance program designed to monitor all aspects of the calibration program and to provide the appropriate feedback mechanism if adjustments are needed. In the United States there are a number of organizations with laboratory accreditation programs. All existing accreditation programs require that the laboratory implement a quality assurance program with essentially the same elements in all of these programs. Collectively, these elements have been designated as a Measurement Quality Assurance (MQA) program. This paper will briefly discuss the interrelationship of the elements of an MQA program. Using the Center for Devices and Radiological Health (CDRH) X-ray Calibration Laboratory (XCL) as an example, it will focus on setting up a quality control program for the equipment in a Secondary Calibration Laboratory.

  12. Development of a quality assurance program for ionizing radiation secondary calibration laboratories

    International Nuclear Information System (INIS)

    Heaton, H.T. II; Taylor, A.R. Jr.

    1993-01-01

    For calibration laboratories, routine calibrations of instruments meeting stated accuracy goals are important. One method of achieving the accuracy goals is to establish and follow a quality assurance program designed to monitor all aspects of the calibration program and to provide the appropriate feedback mechanism if adjustments are needed. In the United States there are a number of organizations with laboratory accreditation programs. All existing accreditation programs require that the laboratory implement a quality assurance program with essentially the same elements in all of these programs. Collectively, these elements have been designated as a Measurement Quality Assurance (MQA) program. This paper will briefly discuss the interrelationship of the elements of an MQA program. Using the Center for Devices and Radiological Health (CDRH) X-ray Calibration Laboratory (XCL) as an example, it will focus on setting up a quality control program for the equipment in a Secondary Calibration Laboratory

  13. Quality assurance in the measurement of internal radioactive contamination and dose assessment and the United States Department of Energy Laboratory Accreditation Program

    International Nuclear Information System (INIS)

    Bhatt, Anita

    2016-01-01

    The Quality Assurance for analytical measurement of internal radioactive contamination and dose assessment in the United States (US) is achieved through the US Department of Energy (DOE) Laboratory Accreditation Program (DOELAP) for both Dosimetry and Radio bioassay laboratories for approximately 150,000 radiation workers. This presentation will explain the link between Quality Assurance and the DOELAP Accreditation process. DOELAP is a DOE complex-wide safety program that ensures the quality of worker radiation protection programs. DOELAP tests the ability of laboratories to accurately measure and quantify radiation dose to workers and assures the laboratories quality systems are capable of defending and sustaining their measurement results. The United States Law in Title 10 of the Code of Federal Regulations 835 requires that personnel Dosimetry and Radio bioassay programs be tested and accredited

  14. Laboratory Directed Research and Development Program FY2016 Annual Summary of Completed Projects

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2017-03-30

    ORNL FY 2016 Annual Summary of Laboratory Directed Research and Development Program (LDRD) Completed Projects. The Laboratory Directed Research and Development (LDRD) program at ORNL operates under the authority of DOE Order 413.2C, “Laboratory Directed Research and Development” (October 22, 2015), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. The LDRD program funds are obtained through a charge to all Laboratory programs. ORNL reports its status to DOE in March of each year.

  15. Valid methods: the quality assurance of test method development, validation, approval, and transfer for veterinary testing laboratories.

    Science.gov (United States)

    Wiegers, Ann L

    2003-07-01

    Third-party accreditation is a valuable tool to demonstrate a laboratory's competence to conduct testing. Accreditation, internationally and in the United States, has been discussed previously. However, accreditation is only I part of establishing data credibility. A validated test method is the first component of a valid measurement system. Validation is defined as confirmation by examination and the provision of objective evidence that the particular requirements for a specific intended use are fulfilled. The international and national standard ISO/IEC 17025 recognizes the importance of validated methods and requires that laboratory-developed methods or methods adopted by the laboratory be appropriate for the intended use. Validated methods are therefore required and their use agreed to by the client (i.e., end users of the test results such as veterinarians, animal health programs, and owners). ISO/IEC 17025 also requires that the introduction of methods developed by the laboratory for its own use be a planned activity conducted by qualified personnel with adequate resources. This article discusses considerations and recommendations for the conduct of veterinary diagnostic test method development, validation, evaluation, approval, and transfer to the user laboratory in the ISO/IEC 17025 environment. These recommendations are based on those of nationally and internationally accepted standards and guidelines, as well as those of reputable and experienced technical bodies. They are also based on the author's experience in the evaluation of method development and transfer projects, validation data, and the implementation of quality management systems in the area of method development.

  16. Technical baseline description for in situ vitrification laboratory test equipment

    International Nuclear Information System (INIS)

    Beard, K.V.; Bonnenberg, R.W.; Watson, L.R.

    1991-09-01

    IN situ vitrification (ISV) has been identified as possible waste treatment technology. ISV was developed by Pacific Northwest Laboratory (PNL), Richland, Washington, as a thermal treatment process to treat contaminated soils in place. The process, which electrically melts and dissolves soils and associated inorganic materials, simultaneously destroys and/or removes organic contaminants while incorporating inorganic contaminants into a stable, glass-like residual product. This Technical Baseline Description has been prepared to provide high level descriptions of the design of the Laboratory Test model, including all design modifications and safety improvements made to data. Furthermore, the Technical Baseline Description provides a basic overview of the interface documents for configuration management, program management interfaces, safety, quality, and security requirements. 8 figs

  17. Fuel Cell Development and Test Laboratory | Energy Systems Integration

    Science.gov (United States)

    Facility | NREL Fuel Cell Development and Test Laboratory Fuel Cell Development and Test Laboratory The Energy System Integration Facility's Fuel Cell Development and Test Laboratory supports fuel cell research and development projects through in-situ fuel cell testing. Photo of a researcher running

  18. Energy Systems High-Pressure Test Laboratory | Energy Systems Integration

    Science.gov (United States)

    Facility | NREL Energy Systems High-Pressure Test Laboratory Energy Systems High-Pressure Test Laboratory In the Energy Systems Integration Facility's High-Pressure Test Laboratory, researchers can safely test high-pressure hydrogen components. Photo of researchers running an experiment with a hydrogen fuel

  19. Quality assurance program in the External dosimetry laboratory of the CPHR

    International Nuclear Information System (INIS)

    Molina P, D.; Pernas S, R.; Martinez H, E.; Cardenas H, J.

    2006-01-01

    From 1999 the Laboratory of External Dosimetry of the Radiation Protection and Hygiene Center comes applying in its service of personal dosimetry a Program of Quality Assurance. This program was designed according to the recommendations of national and international organizations as the National Assuring Office of the Republic of Cuba (ONARC), the International Standards Organization (ISO), the International Electro technique Commission (IEC) and the International Atomic Energy Agency (IAEA). In this work it is presented in a summarized way the operation of this Program of Quality Assurance which includes the administration and conservation of the results and the documentation of the service, the controls that are carried out to the equipment, the acceptance tests that are applied to the equipment and new dosemeters, the shipment and prosecution of the dosemeters, the evaluation, storage and conservation of the doses, the report of the results, the traceability and reproducibility of the measurements, the attention to the reclamations and the clients complaints and the internal and external audits to those that it undergoes periodically the laboratory. (Author)

  20. Summary and recommendations of the NRC/INEL Activated Carbon Testing Program

    International Nuclear Information System (INIS)

    Scarpellino, C.D.; Sill, C.W.

    1986-01-01

    The Committee on Nuclear Air and Gas Treatment (CONAGT) of the American Society of Mechanical Engineers (ASME) sponsored an interlaboratory testing program, round-robin, of nuclear-grade activated carbon. The results of this round-robin revealed gross differences in penetration of radio-labeled methyl iodide as measured by the various laboratories when using Method A of the ASTM D-3803-79 Standard. These differences prompted the Nuclear Regulatory Commission (NRC) to establish the NRC/INEL Activated Carbon Testing Program to determine the causes of these discrepancies and to provide recommendations that could lead to an accurate and reliable testing procedure that would ensure an adequate method for assessing the capability of activated carbon to remove radioiodine from gas streams within commercial nuclear power plants. The NRC/INEL Activated Carbon Testing Program has conducted formal and informal interlaboratory comparisons to identify problems with the test method and its application and to assess the effectiveness of changes to procedures and equipment voluntarily implemented by commercial laboratories to mitigate the disparity of test results. The results of the first formal NRC/INEL Interlaboratory Comparison (IC) essentially verified the CONAGT round-robin results despite the use of a detailed test protocol. This data indicated that many of the participating laboratories probably had been operating outside the ASTM specifications for relative humidity (RH) and flow. In addition, this process provided information which was used to modify the testing protocol employed for the second NRC/INEL Interlaboratory Comparison (IC-2) to make it more rugged and reliable. These changes to the protocol together with the results of INEL sensitivity testing are the basis for the recommendations presented

  1. Quality assurance manual for the Department of Energy laboratory accreditation program for personnel dosimetry systems

    International Nuclear Information System (INIS)

    1987-02-01

    The overall purpose of this document is to establish a uniform approach to quality assurance. This will ensure that uniform, high-quality personnel dosimetry practices are followed by the participating testing laboratories. The document presents guidelines for calibrating and maintaining measurement and test equipment (M and TE), calibrating radiation fields, and subsequently irradiating and handling personnel dosimeters in laboratories involved in the DOE dosimetry systems testing program. Radiation energies for which the test procedures apply are photons with approximately 15 keV to 2 MeV, beta particles above 0.3 MeV, neutrons with approximately 1 keV to 2 MeV. 12 refs., 4 tabs

  2. Laboratory directed research and development program FY 1999

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Todd; Levy, Karin

    2000-03-08

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. This is the annual report on Laboratory Directed Research and Development (LDRD) program for FY99.

  3. Laboratory Directed Research and Development Program FY 2001

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Todd; Levy, Karin

    2002-03-15

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. This is the annual report on Laboratory Directed Research and Development (LDRD) program for FY01.

  4. SSC string test facility for superconducting magnets: Testing capabilities and program for collider magnets

    International Nuclear Information System (INIS)

    Kraushaar, P.; Burgett, W.; Dombeck, T.; McInturff, A.; Robinson, W.; Saladin, V.

    1993-05-01

    The Accelerator Systems String Test (ASST) R ampersand D Testing Facility has been established at the SSC Laboratory to test Collider and High Energy Booster (HEB) superconducting magnet strings. The facility is operational and has had two testing periods utilizing a half cell of collider prototypical magnets with the associated spool pieces and support systems. This paper presents a description of the testing capabilities of the facility with respect to components and supporting subsystems (cryogenic, power, quench protection, controls and instrumentation), the planned testing program for the collider magnets

  5. Evaluation of Mycology Laboratory Proficiency Testing

    OpenAIRE

    Reilly, Andrew A.; Salkin, Ira F.; McGinnis, Michael R.; Gromadzki, Sally; Pasarell, Lester; Kemna, Maggi; Higgins, Nancy; Salfinger, Max

    1999-01-01

    Changes over the last decade in overt proficiency testing (OPT) regulations have been ostensibly directed at improving laboratory performance on patient samples. However, the overt (unblinded) format of the tests and regulatory penalties associated with incorrect values allow and encourage laboratorians to take extra precautions with OPT analytes. As a result OPT may measure optimal laboratory performance instead of the intended target of typical performance attained during routine patient te...

  6. EBR-2 [Experimental Breeder Reactor-2] test programs

    International Nuclear Information System (INIS)

    Sackett, J.I.; Lehto, W.K.; Lindsay, R.W.; Planchon, H.P.; Lambert, J.D.B.; Hill, D.J.

    1990-01-01

    The Experimental Breeder Reactor-2 (EBR-2) is a sodium cooled power reactor supplying about 20 MWe to the Idaho National Engineering Laboratory (INEL) grid and, in addition, is the key component in the development of the Integral Fast Reactor (IFR). EBR-2's testing capability is extensive and has seen four major phases: (1) demonstration of LMFBR power plant feasibility, (2) irradiation testing for fuel and material development, (3) testing the off-normal performance of fuel and plant systems and (4) operation as the IFR prototype, developing and demonstrating the IFR technology associated with fuel and plant design. Specific programs being carried out in support of the IFR include advanced fuels and materials development, advanced control system development, plant diagnostics development and component testing. This paper discusses EBR-2 as the IFR prototype and the associated testing programs. 29 refs

  7. Flood-Fighting Structures Demonstration and Evaluation Program: Laboratory and Field Testing in Vicksburg, Mississippi

    Science.gov (United States)

    2007-07-01

    then it should be disposed of by recycling or land-filling. This material should not be burned due to the formation of carbon dioxide and carbon...and 2-192). A top spreader bar Chapter 2 Laboratory Testing and Evaluation of Expedient Flood-fighting Barriers 135 Figure 2-189

  8. Laboratory Directed Research and Development Program Assessment for FY 2008

    Energy Technology Data Exchange (ETDEWEB)

    Looney, J P; Fox, K J

    2008-03-31

    Brookhaven National Laboratory (BNL) is a multidisciplinary Laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal Year 2008 spending was $531.6 million. There are approximately 2,800 employees, and another 4,300 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development,' April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new 'fundable' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research 'which could lead to new programs, projects, and directions' for the Laboratory. To be a premier scientific Laboratory, BNL must continuously foster groundbreaking scientific research and renew its research agenda. The competition for LDRD funds stimulates Laboratory scientists to think in new and creative ways, which becomes a major factor in achieving and maintaining research excellence and a means to address National needs within the overall mission of the DOE and BNL. By fostering high-risk, exploratory research, the LDRD program helps

  9. Spent fuel storage cask testing and operational experience at the Idaho National Engineering Laboratory

    International Nuclear Information System (INIS)

    Eslinger, L.E.; Schmitt, R.C.

    1989-01-01

    Spent-fuel storage cask research, development, and demonstration activities are being performed for the U.S. Department of Energy's (DOE's) Office of Civilian Radioactive Waste Management (OCRWM) as a part of the storage cask testing program. The cask testing program at federal sites and other locations supports the Nuclear Waste Policy Act (NWPA) and DOE objectives for cooperative demonstrations with the cask vendors and utilities for development of at-reactor dry cask storage capabilities for spent nuclear fuel assemblies. One research and development program for the storage cask performance testing of metal storage cask was initiated through a cooperative agreement between Virginia Power and DOE in 1984. The performance testing was conducted for the DOE and the Electric Power Research Institute by the Pacific Northwest laboratory, operated for DOE by Battelle Memorial Institute, and the Idaho National Engineering Laboratory (INEL), operated for DOE by EG ampersand G Idaho, Inc. In 1988 a cooperative agreement was entered into by DOE with Pacific Sierra Nuclear Associates (PSN) for performance testing of the PSN concrete Ventilated Storage Cask. Another closely related activity involving INEL is a transportable storage cask project identified as the Nuclear Fuel Services Spent-Fuel Shipping/Storage Cask Demonstration Project. The purpose of this project is to demonstrate the feasibility of packing, transporting, and storing commercial spent fuel in dual-purpose transport/storage casks

  10. Laboratory Directed Research and Development Program: FY 2015 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    SLAC,

    2016-04-04

    The Department of Energy (DOE) and the SLAC National Accelerator Laboratory (SLAC) encourage innovation, creativity, originality and quality to maintain the Laboratory’s research activities and staff at the forefront of science and technology. To further advance its scientific research capabilities, the Laboratory allocates a portion of its funds for the Laboratory Directed Research and Development (LDRD) program. With DOE guidance, the LDRD program enables SLAC scientists to make rapid and significant contributions that seed new strategies for solving important national science and technology problems. The LDRD program is conducted using existing research facilities.

  11. Laboratory compliance with the American Society of Clinical Oncology/college of American Pathologists guidelines for human epidermal growth factor receptor 2 testing: a College of American Pathologists survey of 757 laboratories.

    Science.gov (United States)

    Nakhleh, Raouf E; Grimm, Erin E; Idowu, Michael O; Souers, Rhona J; Fitzgibbons, Patrick L

    2010-05-01

    To ensure quality human epidermal growth receptor 2 (HER2) testing in breast cancer, the American Society of Clinical Oncology/College of American Pathologists guidelines were introduced with expected compliance by 2008. To assess the effect these guidelines have had on pathology laboratories and their ability to address key components. In late 2008, a survey was distributed with the HER2 immunohistochemistry (IHC) proficiency testing program. It included questions regarding pathology practice characteristics and assay validation using fluorescence in situ hybridization or another IHC laboratory assay and assessed pathologist HER2 scoring competency. Of the 907 surveys sent, 757 (83.5%) were returned. The median laboratory accessioned 15 000 cases and performed 190 HER2 tests annually. Quantitative computer image analysis was used by 33% of laboratories. In-house fluorescence in situ hybridization was performed in 23% of laboratories, and 60% of laboratories addressed the 6- to 48-hour tissue fixation requirement by embedding tissue on the weekend. HER2 testing was performed on the initial biopsy in 40%, on the resection specimen in 6%, and on either in 56% of laboratories. Testing was validated with only fluorescence in situ hybridization in 47% of laboratories, whereas 10% of laboratories used another IHC assay only; 13% used both assays, and 12% and 15% of laboratories had not validated their assays or chose "not applicable" on the survey question, respectively. The 90% concordance rate with fluorescence in situ hybridization results was achieved by 88% of laboratories for IHC-negative findings and by 81% of laboratories for IHC-positive cases. The 90% concordance rate for laboratories using another IHC assay was achieved by 80% for negative findings and 75% for positive cases. About 91% of laboratories had a pathologist competency assessment program. This survey demonstrates the extent and characteristics of HER2 testing. Although some American Society of

  12. Inquiry-based laboratory investigations and student performance on standardized tests in biological science

    Science.gov (United States)

    Patke, Usha

    Achievement data from the 3rd International Mathematics and Sciences Study and Program for International Student Assessment in science have indicated that Black students from economically disadvantaged families underachieve at alarming rates in comparison to White and economically advantaged peer groups. The study site was a predominately Black, urban school district experiencing underachievement. The purpose of this correlational study was to examine the relationship between students' use of inquiry-based laboratory investigations and their performance on the Biology End of Course Test, as well as to examine the relationship while partialling out the effects of student gender. Constructivist theory formed the theoretical foundation of the study. Students' perceived levels of experience with inquiry-based laboratory investigations were measured using the Laboratory Program Variable Inventory (LPVI) survey. LPVI scores of 256 students were correlated with test scores and were examined by student gender. The Pearson correlation coefficient revealed a small direct correlation between students' experience in inquiry-based laboratory investigation classes and standardized test scores on the Biology EOCT. A partial correlational analysis indicated that the correlation remained after controlling for gender. This study may prompt a change from teacher-centered to student-centered pedagogy at the local site in order to increase academic achievement for all students. The results of this study may also influence administrators and policy makers to initiate local, state, or nationwide curricular development. A change in curriculum may promote social change as students become more competent, and more able, to succeed in life beyond secondary school.

  13. Antimicrobial susceptibility testing by Australian veterinary diagnostic laboratories.

    Science.gov (United States)

    Hardefeldt, L Y; Marenda, M; Crabb, H; Stevenson, M A; Gilkerson, J R; Billman-Jacobe, H; Browning, G F

    2018-04-01

    The national strategy for tackling antimicrobial resistance highlights the need for antimicrobial stewardship in veterinary practice and for surveillance of antimicrobial susceptibility in veterinary pathogens. Diagnostic laboratories have an important role in facilitating both of these processes, but it is unclear whether data from veterinary diagnostic laboratories are similar enough to allow for compilation and if there is consistent promotion of appropriate antimicrobial use embedded in the approaches of different laboratories to susceptibility testing. A cross-sectional study of antimicrobial susceptibility testing and reporting procedures by Australian veterinary diagnostic laboratories was conducted in 2017 using an online questionnaire. All 18 veterinary diagnostic laboratories in Australia completed the questionnaire. Kirby-Bauer disc diffusion was the method predominantly used for antimicrobial susceptibility testing and was used to evaluate 86% of all isolates, although two different protocols were used across the 18 laboratories (CLSI 15/18, CDS 3/18). Minimum inhibitory concentrations were never reported by 61% of laboratories. Common isolates were consistently reported on across all species, except for gram-negative isolates in pigs, for which there was some variation in the approach to reporting. There was considerable diversity in the panels of antimicrobials used for susceptibility testing on common isolates and no consistency was apparent between laboratories for any bacterial species. We recommend that nationally agreed and consistent antimicrobial panels for routine susceptibility testing should be developed and a uniform set of guidelines should be adopted by veterinary diagnostic laboratories in Australia. © 2018 Australian Veterinary Association.

  14. The Validation of NAA Method Used as Test Method in Serpong NAA Laboratory

    International Nuclear Information System (INIS)

    Rina-Mulyaningsih, Th.

    2004-01-01

    The Validation Of NAA Method Used As Test Method In Serpong NAA Laboratory. NAA Method is a non standard testing method. The testing laboratory shall validate its using method to ensure and confirm that it is suitable with application. The validation of NAA methods have been done with the parameters of accuracy, precision, repeatability and selectivity. The NIST 1573a Tomato Leaves, NIES 10C Rice flour unpolished and standard elements were used in this testing program. The result of testing with NIST 1573a showed that the elements of Na, Zn, Al and Mn are met from acceptance criteria of accuracy and precision, whereas Co is rejected. The result of testing with NIES 10C showed that Na and Zn elements are met from acceptance criteria of accuracy and precision, but Mn element is rejected. The result of selectivity test showed that the value of quantity is between 0.1-2.5 μg, depend on the elements. (author)

  15. Laboratory Directed Research and Development Program. Annual report

    Energy Technology Data Exchange (ETDEWEB)

    Ogeka, G.J.

    1991-12-01

    Today, new ideas and opportunities, fostering the advancement of technology, are occurring at an ever-increasing rate. It, therefore, seems appropriate that a vehicle be available which fosters the development of these new ideas and technologies, promotes the early exploration and exploitation of creative and innovative concepts, and which develops new ``fundable`` R&D projects and programs. At Brookhaven National Laboratory (BNL), one such method is through its Laboratory Directed Research and Development (LDRD) Program. This discretionary research and development tool is critical in maintaining the scientific excellence and vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community, fostering new science and technology ideas, which is the major factor achieving and maintaining staff excellence, and a means to address national needs, with the overall mission of the Department of Energy (DOE) and the Brookhaven National Laboratory. The Project Summaries with their accomplishments described in this report reflect the above. Aside from leading to new fundable or promising programs and producing especially noteworthy research, they have resulted in numerous publications in various professional and scientific journals, and presentations at meetings and forums.

  16. US DOE Regional Test Centers Program - 2016 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Stein, Joshua [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-05-01

    The US Department of Energy’s Regional Test Center (RTC) program provides outdoor validation and bankability data for innovative solar technologies at five sites across the US representing a range of climate conditions. Data helps get new technologies to market faster and improves US industry competitiveness. Managed by Sandia National Laboratories and the National Renewable Energy Laboratory (NREL), the RTC program partners with US manufacturers of photovoltaic (PV) technologies, including modules, inverters, and balance-of-system equipment. The study is collaborative, with manufacturers (also known as RTC industry partners) and the national labs working together on a system design and validation strategy that meets a clearly defined set of performance and reliability objectives.

  17. United States Department of Energy commercial reactor spent fuel programs being conducted at the Idaho National Engineering Laboratory

    International Nuclear Information System (INIS)

    Piscitella, R.R.; Rasmussen, T.L.; Uhl, D.L.

    1987-01-01

    The Idaho National Engineering Laboratory participation in OCRWM programs includes the Spent Fuel Storage Cask Testing Program, Dry Rod Consolidation Technology Program, Prototypical Consolidation Demonstration Program, the Nuclear Fuel Services Project, and the Cask Systems Acquisition Program. The DOE has entered into a cooperative agreement with Virginia Power and the Electric Power Research Institute to demonstrate storage of commercial spent fuel in steel storage casks. The Program conducted heat transfer and shielding tests with three storage casks with intact spent fuel assemblies and two casks with consolidated spent fuel rods, one of which was previously tested with intact fuel, and provides test information in support of Virginia Power's at-reactor dry storage licensing effort. 3 figs., 1 tab

  18. PBF/LOFT Lead Rod Test Program experiment operating specification

    International Nuclear Information System (INIS)

    Varacalle, D.J. Jr.

    1978-11-01

    The PBF/LOFT Lead Rod (LLR) Test Program is being conducted to provide experimental information on the behavior of nuclear fuel under normal and accident conditions in the Power Burst Facility at the Idaho National Engineering Laboratory. Understanding the behavior of light-water reactors (LWR) under loss-of-coolant conditions is a major objective of the NRC Reactor Safety Research Program. The Loss of Fluid Test (LOFT) facility is the major testing facility to evaluate the systems response of an LWR over a wide range of Loss of Coolant Experment (LOCE) conditions. As such, the LOFT core is intended to be used for sequential LOCE tests provided no significant fuel rod failures occur. The PFB/LLR tests are designed to simulate the test conditions for the LOFT Power Ascension Tests L2-2 through L2-5. The test program has been designed to provide a parametric evaluation of the LOFT fuel over a wide range of power. Thus, a relatively accurate assessment of the state of the LOFT core after the completion of each subtest and the anticipated effect of the next test can be obtained by utilizing a combination of LLR test data and analytical predictions. Specifications for the test program are presented

  19. Sandia National Laboratories, California Environmental Management System Program Manual.

    Energy Technology Data Exchange (ETDEWEB)

    2009-04-01

    The Sandia National Laboratories, California (SNL/CA) Environmental Management System (EMS) Program Manual documents the elements of the site EMS Program. The SNL/CA EMS Program conforms to the International Standard on Environmental Management Systems, ISO 14001:2004 and Department of Energy (DOE) Order 450.1. Sandia National Laboratories, California (SNL/CA) has maintained functional environmental programs to assist with regulatory compliance for more than 30 years. During 2005, these existing programs were rolled into a formal environmental management system (EMS) that expands beyond the traditional compliance focus to managing and improving environmental performance and stewardship practices for all site activities. An EMS is a set of inter-related elements that represent a continuing cycle of planning, implementing, evaluating, and improving processes and actions undertaken to achieve environmental policy and goals. The SNL/CA EMS Program conforms to the International Standard for Environmental Management Systems, ISO 14001:2004 (ISO 2004). The site received ISO 14001 certification in September 2006. SNL/CA's EMS Program is applicable to the Sandia, Livermore site only. Although SNL/CA operates as one organizational division of the overall Sandia National Laboratories, the EMS Program is site-specific, with site-specific objectives and targets. SNL/CA (Division 8000) benefits from the organizational structure as it provides corporate level policies, procedures, and standards, and established processes that connect to and support elements of the SNL/CA EMS Program. Additionally, SNL/CA's EMS Program benefits from two corporate functional programs (Facilities Energy Management and Fleet Services Environmental programs) that maintain responsibility for energy management and fleet services for all Sandia locations. Each EMS element is further enhanced with site-specific processes and standards. Division 8000 has several groups operating at Sandia

  20. Sandia National Laboratories, California Environmental Management System program manual.

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, Barbara L.

    2012-03-01

    The Sandia National Laboratories, California (SNL/CA) Environmental Management System (EMS) Program Manual documents the elements of the site EMS Program. The SNL/CA EMS Program conforms to the International Standard on Environmental Management Systems, ISO 14001:2004and Department of Energy (DOE) Order 436.1. Sandia National Laboratories, California (SNL/CA) has maintained functional environmental programs to assist with regulatory compliance for more than 30 years. During 2005, these existing programs were rolled into a formal environmental management system (EMS) that expands beyond the traditional compliance focus to managing and improving environmental performance and stewardship practices for all site activities. An EMS is a set of inter-related elements that represent a continuing cycle of planning, implementing, evaluating, and improving processes and actions undertaken to achieve environmental policy and goals. The SNL/CA EMS Program conforms to the International Standard for Environmental Management Systems, ISO 14001:2004 (ISO 2004). The site first received ISO 14001 certification in September 2006 and recertification in 2009. SNL/CA's EMS Program is applicable to the Sandia, Livermore site only. Although SNL/CA operates as one organizational division of the overall Sandia National Laboratories, the EMS Program is site-specific, with site-specific objectives and targets. SNL/CA (Division 8000) benefits from the organizational structure as it provides corporate level policies, procedures, and standards, and established processes that connect to and support elements of the SNL/CA EMS Program. Additionally, SNL/CA's EMS Program benefits from two corporate functional programs (Facilities Energy and Water Resource Management and Fleet Services programs) that maintain responsibility for energy management and fleet services for all Sandia locations. Each EMS element is further enhanced with site-specific processes and standards. Division 8000 has

  1. Sandia National Laboratories, California Environmental Management System Program Manual.

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, Barbara L.

    2011-04-01

    The Sandia National Laboratories, California (SNL/CA) Environmental Management System (EMS) Program Manual documents the elements of the site EMS Program. The SNL/CA EMS Program conforms to the International Standard on Environmental Management Systems, ISO 14001:2004and Department of Energy (DOE) Order 450.1. Sandia National Laboratories, California (SNL/CA) has maintained functional environmental programs to assist with regulatory compliance for more than 30 years. During 2005, these existing programs were rolled into a formal environmental management system (EMS) that expands beyond the traditional compliance focus to managing and improving environmental performance and stewardship practices for all site activities. An EMS is a set of inter-related elements that represent a continuing cycle of planning, implementing, evaluating, and improving processes and actions undertaken to achieve environmental policy and goals. The SNL/CA EMS Program conforms to the International Standard for Environmental Management Systems, ISO 14001:2004 (ISO 2004). The site received ISO 14001 certification in September 2006. SNL/CA's EMS Program is applicable to the Sandia, Livermore site only. Although SNL/CA operates as one organizational division of the overall Sandia National Laboratories, the EMS Program is site-specific, with site-specific objectives and targets. SNL/CA (Division 8000) benefits from the organizational structure as it provides corporate level policies, procedures, and standards, and established processes that connect to and support elements of the SNL/CA EMS Program. Additionally, SNL/CA's EMS Program benefits from two corporate functional programs (Facilities Energy Management and Fleet Services programs) that maintain responsibility for energy management and fleet services for all Sandia locations. Each EMS element is further enhanced with site-specific processes and standards. Division 8000 has several groups operating at Sandia National Laboratories

  2. Viability testing of material derived from Mycobacterium tuberculosis prior to removal from a containment level-III laboratory as part of a Laboratory Risk Assessment Program.

    Science.gov (United States)

    Blackwood, Kym S; Burdz, Tamara V; Turenne, Christine Y; Sharma, Meenu K; Kabani, Amin M; Wolfe, Joyce N

    2005-01-24

    In the field of clinical mycobacteriology, Mycobacterium tuberculosis (MTB) can be a difficult organism to manipulate due to the restrictive environment of a containment level 3 (CL3) laboratory. Tests for rapid diagnostic work involving smears and molecular methods do not require CL3 practices after the organism has been rendered non-viable. While it has been assumed that after organism deactivation these techniques can be performed outside of a CL3, no conclusive study has consistently confirmed that the organisms are noninfectious after the theoretical 'deactivation' steps. Previous studies have shown that initial steps (such as heating/chemical fixation) may not consistently kill MTB organisms. An inclusive viability study (n = 226) was undertaken to determine at which point handling of culture extraction materials does not necessitate a CL3 environment. Four different laboratory protocols tested for viability included: standard DNA extractions for IS6110 fingerprinting, crude DNA preparations for PCR by boiling and mechanical lysis, protein extractions, and smear preparations. For each protocol, laboratory staff planted a proportion of the resulting material to Bactec 12B medium that was observed for growth for 8 weeks. Of the 208 isolates initially tested, 21 samples grew within the 8-week period. Sixteen (7.7%) of these yielded positive results for MTB that included samples of: deactivated culture resuspensions exposed to 80 degrees C for 20 minutes, smear preparations and protein extractions. Test procedures were consequently modified and tested again (n = 18), resulting in 0% viability. This study demonstrates that it cannot be assumed that conventional practices (i.e. smear preparation) or extraction techniques render the organism non-viable. All methodologies, new and existing, should be examined by individual laboratories to validate the safe removal of material derived from MTB to the outside of a CL3 laboratory. This process is vital to establish in

  3. Viability testing of material derived from Mycobacterium tuberculosis prior to removal from a Containment Level-III Laboratory as part of a Laboratory Risk Assessment Program

    Directory of Open Access Journals (Sweden)

    Kabani Amin M

    2005-01-01

    Full Text Available Abstract Background In the field of clinical mycobacteriology, Mycobacterium tuberculosis (MTB can be a difficult organism to manipulate due to the restrictive environment of a containment level 3 (CL3 laboratory. Tests for rapid diagnostic work involving smears and molecular methods do not require CL3 practices after the organism has been rendered non-viable. While it has been assumed that after organism deactivation these techniques can be performed outside of a CL3, no conclusive study has consistently confirmed that the organisms are noninfectious after the theoretical 'deactivation' steps. Previous studies have shown that initial steps (such as heating /chemical fixation may not consistently kill MTB organisms. Methods An inclusive viability study (n = 226 was undertaken to determine at which point handling of culture extraction materials does not necessitate a CL3 environment. Four different laboratory protocols tested for viability included: standard DNA extractions for IS6110 fingerprinting, crude DNA preparations for PCR by boiling and mechanical lysis, protein extractions, and smear preparations. For each protocol, laboratory staff planted a proportion of the resulting material to Bactec 12B medium that was observed for growth for 8 weeks. Results Of the 208 isolates initially tested, 21 samples grew within the 8-week period. Sixteen (7.7% of these yielded positive results for MTB that included samples of: deactivated culture resuspensions exposed to 80°C for 20 minutes, smear preparations and protein extractions. Test procedures were consequently modified and tested again (n = 18, resulting in 0% viability. Conclusions This study demonstrates that it cannot be assumed that conventional practices (i.e. smear preparation or extraction techniques render the organism non-viable. All methodologies, new and existing, should be examined by individual laboratories to validate the safe removal of material derived from MTB to the outside of a

  4. Laboratory Directed Research and Development Program Assessment for FY 2014

    Energy Technology Data Exchange (ETDEWEB)

    Hatton, D. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2014-03-01

    Each year, Brookhaven National Laboratory (BNL) is required to provide a program description and overview of its Laboratory Directed Research and Development Program (LDRD) to the Department of Energy in accordance with DOE Order 413.2B dated April 19, 2006. This report fulfills that requirement.

  5. Applying the National Industrial Security Program (NISP) in the laboratory environment

    International Nuclear Information System (INIS)

    Bruckner, D.G.

    1995-01-01

    With continuing changes in the world safeguards and security environment the effectiveness of many laboratory operations depends on correctly assessing the risk to its programs and developing protection technologies, research and concepts of operations being employed by the scientific community. This paper explores the opportunities afforded by the National Industrial Security Program (NISP) to uniformly and simply protect Laboratory security assets, sensitive and classified information and matter, during all aspects of a laboratory program. The developments in information systems, program security, physical security and access controls suggest an industrial security approach. This paper's overall objective is to indicate that the Laboratory environment is particularly well suited to take advantage being pursued by NISP and the performance objectives of the new DOE orders

  6. IPEP: Laboratory performance evaluation reports for management of DOE EM programs

    International Nuclear Information System (INIS)

    Hensley, J.E.; Lindahl, P.C.; Streets, W.E.

    1995-01-01

    Environmental restoration program/project managers at DOE's Office of Environmental Management (EM) are making important decisions based on analytical data generated by contracted laboratories. The Analytical Services Division, EM-263, is developing the Integrated Performance Evaluation Program (IPEP) to assess the performance of those laboratories, based on results from Performance Evaluation (PE) programs. The IPEP reports will be used by the laboratories to foster self-assessment and improvement. In addition, IPEP will produce PE reports for three levels of EM management (Operations/Project Offices, Area Program Offices, and Deputy Assistant Secretary Office). These reports will be used to assess whether contracted analytical laboratories have the capability to produce environmental data of the quality necessary for making environmental restoration and waste management decisions

  7. Educational digital resource for data analysis of Civil Engineering laboratory tests

    OpenAIRE

    Gustavo Henrique Nalon; Paulo Sergio de Almeida Barbosa; Walcyr Duarte Nascimento

    2018-01-01

    This work aims to implement and evaluate an interactive educational software that helps Civil Engineering students to perform and analyze the calculations related to different Soil Mechanics laboratory tests. This experience consists of an attempt to incorporate information and communication technologies (ICTs) into the engineering teaching-learning process. The content of the program is distributed into three different modules: “Compaction test”, “Consolidation test”, and “Direct shear test”...

  8. Laboratory Directed Research and Development Program Activities for FY 2008.

    Energy Technology Data Exchange (ETDEWEB)

    Looney,J.P.; Fox, K.

    2009-04-01

    Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that maintains a primary mission focus the physical sciences, energy sciences, and life sciences, with additional expertise in environmental sciences, energy technologies, and national security. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal year 2008 budget was $531.6 million. There are about 2,800 employees, and another 4,300 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development,' April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Developlnent at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. Accordingly, this is our Annual Report in which we describe the Purpose, Approach, Technical Progress and Results, and Specific Accomplishments of all LDRD projects that received funding during Fiscal Year 2008. BNL expended $12 million during Fiscal Year 2008 in support of 69 projects. The program has two categories, the annual Open Call LDRDs and Strategic LDRDs, which combine to meet the overall objectives of the LDRD Program. Proposals are solicited annually for review and approval concurrent with the next fiscal year, October 1. For the open call for proposals, an LDRD Selection Committee, comprised of the Associate Laboratory Directors (ALDs) for the Scientific Directorates, an equal number of scientists recommended by the Brookhaven Council, plus the Assistant Laboratory Director for Policy and Strategic Planning, review the proposals submitted in response to the solicitation. The Open Can LDRD category emphasizes innovative research concepts

  9. Establishing a national biological laboratory safety and security monitoring program.

    Science.gov (United States)

    Blaine, James W

    2012-12-01

    The growing concern over the potential use of biological agents as weapons and the continuing work of the Biological Weapons Convention has promoted an interest in establishing national biological laboratory biosafety and biosecurity monitoring programs. The challenges and issues that should be considered by governments, or organizations, embarking on the creation of a biological laboratory biosafety and biosecurity monitoring program are discussed in this article. The discussion focuses on the following questions: Is there critical infrastructure support available? What should be the program focus? Who should be monitored? Who should do the monitoring? How extensive should the monitoring be? What standards and requirements should be used? What are the consequences if a laboratory does not meet the requirements or is not willing to comply? Would the program achieve the results intended? What are the program costs? The success of a monitoring program can depend on how the government, or organization, responds to these questions.

  10. Participation of the Laboratorio de Radiotoxicologia of IPEN, SP, Brazil, in laboratory inter-comparison programs

    International Nuclear Information System (INIS)

    Mesquita, Sueli Alexandra de; Carneiro, Janete Cristina G.

    2005-01-01

    The Radiotoxicology Laboratory (LRT) of IPEN/CNEN-SP has as mission to assess internal internal contamination from individuals through qualitative and quantitative analysis of radionuclides present in biological samples. The LRT is able to meet the demand for in vitro monitoring and radiological and nuclear emergencies, both in the case of occupational exposures, as individuals. With the purpose of increasing the reliability of the test results, and keeping it up to date on new analytical techniques, the LRT participates annually in two laboratory inter-comparison programs: a national, the PNI (Programa Nacional de Intercomparacao), promoted by IRD/CNEN and an international from PROCORAD (Association for the Promotion of Quality Controls in Radiotoxicological Bioassay). The present work shows the performance of the LRT by means of the results obtained in the exercises for the quantification of natural uranium and uranium isotopes, promoted by both the inter-comparison programs in the year of 2004. The analysis of the obtained results demonstrates the good performance achieved by LRT, and confirms the sustainability of its quality system, required in calibration and testing laboratories

  11. Federal laboratory nondestructive testing research and development applicable to industry

    Energy Technology Data Exchange (ETDEWEB)

    Smith, S.A.; Moore, N.L.

    1987-02-01

    This document presents the results of a survey of nondestructive testing (NDT) and related sensor technology research and development (R and D) at selected federal laboratories. Objective was to identify and characterize NDT activities that could be applied to improving energy efficiency and overall productivity in US manufacturing. Numerous federally supported R and D programs were identified in areas such as acoustic emissions, eddy current, radiography, computer tomography and ultrasonics. A Preliminary Findings Report was sent to industry representatives, which generated considerable interest.

  12. The Italian pilot external quality assessment program for cystic fibrosis sweat test.

    Science.gov (United States)

    Salvatore, Marco; Floridia, Giovanna; Amato, Annalisa; Censi, Federica; Carta, Claudio; de Stefano, Maria Chiara; Ferrari, Gianluca; Tosto, Fabrizio; Capoluongo, Ettore; Caruso, Ubaldo; Castaldo, Giuseppe; Cirilli, Natalia; Corbetta, Carlo; Padoan, Rita; Raia, Valeria; Taruscio, Domenica

    2016-05-01

    Sweat chloride test is the gold standard test for cystic fibrosis (CF) diagnosis. In 2014 the Istituto Superiore di Sanità established the Italian pilot external quality assessment program for CF sweat test (IEQA-ST). Ten laboratories, included among the 33 Italian CF Referral Centers, were selected and enrolled on the basis of their attitude to perform sweat test (ST) analysis by using methods recommended by the Italian Guidelines. They received three different sweat-like samples (normal, borderline and pathologic chloride concentration), with mock clinical indications, for analysis according to routine procedures. Assessment, performed by a panel of experts, covered analytical performance, interpretation and reporting of results; categories of "poor" and "satisfactory" performance were not defined. All data were managed through a web utility. The program identified important areas of interest and, in some case, of concern. It is important to underline that results are referred to a small proportion, i.e. about 30%, of Italian laboratories performing CF ST in the context of the Referral Centers. Data collected highlight the importance of participation in EQA programs as it may improve laboratory/clinical performance; our study represents a model for the setting up of a large-scale EQA scheme for ST. Copyright © 2016 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  13. Lawrence Livermore Laboratory Nuclear Test Effects and Geologic Data Bank

    International Nuclear Information System (INIS)

    Howard, N.W.

    1976-01-01

    Data on the geology of the USERDA Nevada Test Site have been collected for the purpose of evaluating the possibility of release of radioactivity at proposed underground nuclear test sites. These data, including both the rock physical properties and the geologic structure and stratigraphy of a large number of drill-hole sites, are stored in the Lawrence Livermore Laboratory Earth Sciences Division Nuclear Test Effects and Geologic Data Bank. Retrieval programs can quickly provide a geological and geophysical comparison of a particular site with other sites where radioactivity was successfully contained. The data can be automatically sorted, compared, and averaged, and information listed according to site location, drill-hole construction, rock units, depth to key horizons and to the water table, and distance to faults. These programs also make possible ordered listings of geophysical properties (interval bulk density, overburden density, interval velocity, velocity to the surface, grain density, water content, carbonate content, porosity, and saturation of the rocks). The characteristics and capabilities of the data bank are discussed

  14. Accelerated Leach Test(s) Program. Annual report

    International Nuclear Information System (INIS)

    Dougherty, D.R.; Fuhrmann, M.; Colombo, P.

    1985-09-01

    This report summarizes the work performed for the Accelerated Leach Test(s) Program at Brookhaven National Laboratory in Fiscal Year 1985 under the sponsorship of the US Department of Energy's Low-Level Waste Management Program (LLWMP). Programmatic activities were concentrated in three areas, as listed and described in the following paragraphs. (1) A literature survey of reported leaching mechanisms, available mathematical models and factors that affect leaching of LLW forms has been compiled. Mechanisms which have been identified include diffusion, dissolution, ion exchange, corrosion and surface effects. Available mathematical models are based on diffusion as the predominant mechanism. Although numerous factors that affect leaching have been identified, they have been conveniently categorized as factors related to the entire leaching system, to the leachant or to the waste form. A report has been published on the results of this literature survey. (2) A computerized data base of LLW leaching data and mathematical models is being developed. The data are being used for model evaluation by curve fitting and statistical analysis according to standard procedures of statistical quality control. (3) Long-term tests on portland cement, bitumen and vinyl ester-styrene (VES) polymer waste forms are underway which are designed to identify and evaluate factors that accelerate leaching without changing the mechanisms. Results on the effect of temperature on leachability indicate that the leach rates of cement and VES waste forms increase with increasing temperature, whereas, the leach rate of bitumen is little affected

  15. HPV testing for primary cervical screening: Laboratory issues and evolving requirements for robust quality assurance.

    Science.gov (United States)

    Carozzi, Francesca Maria; Del Mistro, Annarosa; Cuschieri, Kate; Frayle, Helena; Sani, Cristina; Burroni, Elena

    2016-03-01

    This review aims to highlight the importance of Quality Assurance for Laboratories performing HPV test for Cervical Cancer Screening. An HPV test, to be used as primary screening test, must be validated according to international criteria, based on comparison of its clinical accuracy to HC2 or GP5+/6+ PCR-EIA tests. The number of validated platforms is increasing and appropriate Quality Assurance Programs (QAPs) which can interrogate longitudinal robustness and quality are paramount. This document describes the following topics: (1) the characteristics of an HPV laboratory and the personnel training needs, to ensure an elevated quality of the entire process and the optimal use of the resources; (2) the Quality Assurance, as both internal (IQA) and external quality assessment (EQA) systems, to be implemented and performed, and the description of the existing EQAs, including limitations; (3) general considerations for an optimal EQA program for hrHPV primary screening Due to the importance of Quality Assurance for this field, international efforts are necessary to improve QA International Collaboration. Copyright © 2015 Elsevier B.V. All rights reserved.

  16. BNL NONLINEAR PRE TEST SEISMIC ANALYSIS FOR THE NUPEC ULTIMATE STRENGTH PIPING TEST PROGRAM

    International Nuclear Information System (INIS)

    DEGRASSI, G.; HOFMAYER, C.; MURPHY, C.; SUZUKI, K.; NAMITA, Y.

    2003-01-01

    The Nuclear Power Engineering Corporation (NUPEC) of Japan has been conducting a multi-year research program to investigate the behavior of nuclear power plant piping systems under large seismic loads. The objectives of the program are: to develop a better understanding of the elasto-plastic response and ultimate strength of nuclear piping; to ascertain the seismic safety margin of current piping design codes; and to assess new piping code allowable stress rules. Under this program, NUPEC has performed a large-scale seismic proving test of a representative nuclear power plant piping system. In support of the proving test, a series of materials tests, static and dynamic piping component tests, and seismic tests of simplified piping systems have also been performed. As part of collaborative efforts between the United States and Japan on seismic issues, the US Nuclear Regulatory Commission (USNRC) and its contractor, the Brookhaven National Laboratory (BNL), are participating in this research program by performing pre-test and post-test analyses, and by evaluating the significance of the program results with regard to safety margins. This paper describes BNL's pre-test analysis to predict the elasto-plastic response for one of NUPEC's simplified piping system seismic tests. The capability to simulate the anticipated ratcheting response of the system was of particular interest. Analyses were performed using classical bilinear and multilinear kinematic hardening models as well as a nonlinear kinematic hardening model. Comparisons of analysis results for each plasticity model against test results for a static cycling elbow component test and for a simplified piping system seismic test are presented in the paper

  17. PROGRAM ASTEC (ADVANCED SOLAR TURBO ELECTRIC CONCEPT). PART 1. CANDIDATE MATERIALS LABORATORY TESTS

    Science.gov (United States)

    A space power system of the type envisioned by the ASTEC program requires the development of a lightweight solar collector of high reflectance...capable of withstanding the space environment for an extended period. A survey of the environment of interest for ASTEC purposes revealed 4 potential...developed by the solar-collector industry for use in the ASTEC program, and to test the effects of space environment on these materials. Of 6 material

  18. Variability of ethics education in laboratory medicine training programs: results of an international survey.

    Science.gov (United States)

    Bruns, David E; Burtis, Carl A; Gronowski, Ann M; McQueen, Matthew J; Newman, Anthony; Jonsson, Jon J

    2015-03-10

    Ethical considerations are increasingly important in medicine. We aimed to determine the mode and extent of teaching of ethics in training programs in clinical chemistry and laboratory medicine. We developed an on-line survey of teaching in areas of ethics relevant to laboratory medicine. Reponses were invited from directors of training programs who were recruited via email to leaders of national organizations. The survey was completed by 80 directors from 24 countries who directed 113 programs. The largest numbers of respondents directed postdoctoral training of scientists (42%) or physicians (33%), post-masters degree programs (33%), and PhD programs (29%). Most programs (82%) were 2years or longer in duration. Formal training was offered in research ethics by 39%, medical ethics by 31%, professional ethics by 24% and business ethics by 9%. The number of reported hours of formal training varied widely, e.g., from 0 to >15h/year for research ethics and from 0 to >15h for medical ethics. Ethics training was required and/or tested in 75% of programs that offered training. A majority (54%) of respondents reported plans to add or enhance training in ethics; many indicated a desire for online resources related to ethics, especially resources with self-assessment tools. Formal teaching of ethics is absent from many training programs in clinical chemistry and laboratory medicine, with heterogeneity in the extent and methods of ethics training among the programs that provide the training. A perceived need exists for online training tools, especially tools with self-assessment components. Copyright © 2014 Elsevier B.V. All rights reserved.

  19. Reducing turnaround time for laboratory test results does not improve retention of stable HIV-infected adults on POV program: experience from Uganda.

    Science.gov (United States)

    Maselle, Edna; Muhanguzi, Asaph; Muhumuza, Simon; Nansubuga, Jeniffer; Nawavvu, Cecilia; Namusobya, Jeniffer; Kamya, Moses R; Semitala, Fred C

    2014-01-01

    HIV/ AIDS clinics in resource limited settings (RLS) face increasing numbers of patients and workforce shortage [1, 2]. To address these challenges, efficient models of care like pharmacy only visits (POV) and nurse only visits (NOV) are recommended [3]. The Makerere University Joint AIDS Program (MJAP), a PEPFAR funded program providing care to over 42,000 HIV infected adults has implemented the POV model since 2009. In this model, stable patients on antiretroviral therapy (ART) with adherence to ART >95% and Karnofsky score >90% are reviewed by a doctor every four months but visit pharmacy for ART re-fills every two months. A study conducted in August 2011 showed low retention on the POV program with symptomatic diseases, pending CD4 count, complete blood count results, and poor adherence to ART as the major reasons for the non-retention in the POV program. To improve retention on POV, the TAT (Turnaround Time) for laboratory results (the main reason for non-retention in the previous study) was reduced from one month to one week. In August 2012, the study was repeated to assess the effect of reducing TAT on improving retention one year after patients were placed on POV. A cohort analysis of data from patients in August 2011 and in August 2012 on POV was done. We compared retention of POV before and after reducing the TAT for laboratory results. Retention on POV was 12.0% (95% CI 9.50-14.7) among 619 patients in 2011, (70% Females), mean age was 33 years, Standard Deviation (SD) 8.5 compared to 11.1% (95% CI 9.15-13.4) among 888 patients (70% Females), mean age 38.3 years, SD 8.9 in 2012 (p=0.59). The main reasons for non-retention on the POV program in 2012 were poor adherence to ART (23%) and missed clinic appointments (14%). Reducing TAT for laboratory test results did not improve retention of stable HIV-infected adults on POV in our clinic. Strategies for improving adherence to ART and keeping clinic appointments need to be employed to balance workload and

  20. 2016 Fermilab Laboratory Directed Research & Development Program Plan

    Energy Technology Data Exchange (ETDEWEB)

    Wester, W. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

    2016-05-25

    Fermilab is executing Laboratory Directed Research and Development (LDRD) as outlined by order DOE O 413.2B in order to enhance and realize the mission of the laboratory in a manner that also supports the laboratory’s strategic objectives and the mission of the Department of Energy. LDRD funds enable scientific creativity, allow for exploration of “high risk, high payoff” research, and allow for the demonstration of new ideas, technical concepts, and devices. LDRD also has an objective of maintaining and enhancing the scientific and technical vitality of Fermilab. LDRD is able to fund employee-initiated proposals that address the current strategic objectives and better position Fermilab for future mission needs. The request for such funds is made in consideration of the investment needs, affordability, and directives from DOE and Congress. Review procedures of the proposals will insure that those proposals which most address the strategic goals of the DOE and the Laboratory or which best position Fermilab for the future will be recommended to the Laboratory Director who has responsibility for approval. The execution of each approved project will be the responsibility of the Principal Investigator, PI, who will follow existing Laboratory guidelines to ensure compliance with safety, environmental, and quality assurance practices. A Laboratory Director-appointed LDRD Coordinator will work with Committees, Laboratory Management, other Fermilab Staff, and the PI’s to oversee the implementation of policies and procedures of LDRD and provide the management and execution of this Annual Program Plan. FY16 represents third fiscal year in which LDRD has existed at Fermilab. The number of preliminary proposals (117) submitted in response to the LDRD Call for Proposals indicates very strong interest of the program within the Fermilab community. The first two Calls have resulted in thirteen active LDRD projects – and it is expected that between five and seven new

  1. Laboratory Directed Research and Development Program Activities for FY 2007.

    Energy Technology Data Exchange (ETDEWEB)

    Newman,L.

    2007-12-31

    Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal year 2007 budget was $515 million. There are about 2,600 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development', April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. In accordance this is our Annual Report in which we describe the Purpose, Approach, Technical Progress and Results, and Specific Accomplishments of all LDRD projects that received funding during Fiscal Year 2007. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new 'fundable' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research 'which could lead to new programs, projects, and directions' for the Laboratory. We explicitly indicate that research conducted under the LDRD Program should be highly innovative, and an element of high risk as to success is acceptable. In the solicitation for new proposals for Fiscal Year 2007 we especially requested innovative new projects in

  2. Total laboratory automation: Do stat tests still matter?

    Science.gov (United States)

    Dolci, Alberto; Giavarina, Davide; Pasqualetti, Sara; Szőke, Dominika; Panteghini, Mauro

    2017-07-01

    During the past decades the healthcare systems have rapidly changed and today hospital care is primarily advocated for critical patients and acute treatments, for which laboratory test results are crucial and need to be always reported in predictably short turnaround time (TAT). Laboratories in the hospital setting can face this challenge by changing their organization from a compartmentalized laboratory department toward a decision making-based laboratory department. This requires the implementation of a core laboratory, that exploits total laboratory automation (TLA) using technological innovation in analytical platforms, track systems and information technology, including middleware, and a number of satellite specialized laboratory sections cooperating with care teams for specific medical conditions. In this laboratory department model, the short TAT for all first-line tests performed by TLA in the core laboratory represents the key paradigm, where no more stat testing is required because all samples are handled in real-time and (auto)validated results dispatched in a time that fulfills clinical needs. To optimally reach this goal, laboratories should be actively involved in managing all the steps covering the total examination process, speeding up also extra-laboratory phases, such sample delivery. Furthermore, to warrant effectiveness and not only efficiency, all the processes, e.g. specimen integrity check, should be managed by middleware through a predefined set of rules defined in light of the clinical governance. Crown Copyright © 2017. Published by Elsevier Inc. All rights reserved.

  3. Establishing benchmarks and metrics for disruptive technologies, inappropriate and obsolete tests in the clinical laboratory.

    Science.gov (United States)

    Kiechle, Frederick L; Arcenas, Rodney C; Rogers, Linda C

    2014-01-01

    Benchmarks and metrics related to laboratory test utilization are based on evidence-based medical literature that may suffer from a positive publication bias. Guidelines are only as good as the data reviewed to create them. Disruptive technologies require time for appropriate use to be established before utilization review will be meaningful. Metrics include monitoring the use of obsolete tests and the inappropriate use of lab tests. Test utilization by clients in a hospital outreach program can be used to monitor the impact of new clients on lab workload. A multi-disciplinary laboratory utilization committee is the most effective tool for modifying bad habits, and reviewing and approving new tests for the lab formulary or by sending them out to a reference lab. Copyright © 2013 Elsevier B.V. All rights reserved.

  4. Sensitivity and Specificity of Clinical and Laboratory Otolith Function Tests.

    Science.gov (United States)

    Kumar, Lokesh; Thakar, Alok; Thakur, Bhaskar; Sikka, Kapil

    2017-10-01

    To evaluate clinic based and laboratory tests of otolith function for their sensitivity and specificity in demarcating unilateral compensated complete vestibular deficit from normal. Prospective cross-sectional study. Tertiary care hospital vestibular physiology laboratory. Control group-30 healthy adults, 20-45 years age; Case group-15 subjects post vestibular shwannoma excision or post-labyrinthectomy with compensated unilateral complete audio-vestibular loss. Otolith function evaluation by precise clinical testing (head tilt test-HTT; subjective visual vertical-SVV) and laboratory testing (headroll-eye counterroll-HR-ECR; vesibular evoked myogenic potentials-cVEMP). Sensitivity and specificity of clinical and laboratory tests in differentiating case and control subjects. Measurable test results were universally obtained with clinical otolith tests (SVV; HTT) but not with laboratory tests. The HR-ECR test did not indicate any definitive wave forms in 10% controls and 26% cases. cVEMP responses were absent in 10% controls.HTT test with normative cutoff at 2 degrees deviations from vertical noted as 93.33% sensitive and 100% specific. SVV test with normative cutoff at 1.3 degrees noted as 100% sensitive and 100% specific. Laboratory tests demonstrated poorer specificities owing primarily to significant unresponsiveness in normal controls. Clinical otolith function tests, if conducted with precision, demonstrate greater ability than laboratory testing in discriminating normal controls from cases with unilateral complete compensated vestibular dysfunction.

  5. The accreditation programs and proficiency test in Taiwan for personnel dosimeter services (1991-1998)

    International Nuclear Information System (INIS)

    Lee, B.T.; Hwang, W.S.; Su, S.H.

    2000-01-01

    According to the ionizing radiation safety regulation approved by the ROC Atomic Energy Council (AEC), personnel dosimeter processors shall be accredited by the Chinese National Laboratory Accreditation (CNLA) program before offering dosimeter services and shall be accredited every two years (now has been rescheduled to be every three years since 1996). The aim of this program is to secure quality and technical capability of personnel dosimeters, and to provide systematic improvement for the internal calibration and testing laboratory applying for accreditation by means of assessment procedures. The criteria used to evaluate the capability at laboratories are ISO/IEC 25 (1990) and technical guide in different accreditation fields. The Institute of Nuclear Energy Research (INER) was entrusted by CNLA as the central laboratory to perform the proficiency test of personnel dosimeters for laboratory accreditation in December 1990. Such proficiency tests, based on ANSI N13.11 (1983), which is mainly separated to accident categories and protection categories which consists of eight parts of tests including single and mixture radiation of x-ray, gamma, beta and neutron, have been conducted four times, in 1991, 1993, 1995 and 1998. This paper deals with the test procedures and results of proficiency tests of personnel dosimeters from 1991 until 1998. The results of the four proficiency tests showed that, for accident categories, the pass rate is about 91%; for protection categories, the pass rate is about 98%. Meanwhile, the central laboratory will adopt a new version of HPS N13.11 (1993) to replace ANSI N13.11 (1983) as new criteria for the next proficiency test to be conducted in 2001. (author)

  6. Oil spill sorbents: Testing protocol and certification listing program

    International Nuclear Information System (INIS)

    Cooper, D.; Gausemel, I.

    1993-01-01

    Environment Canada's Emergencies Engineering Division is spearheading a program in conjunction with the Canadian General Standards Board that would see the development of a certification and listing program in addition to a national standard for the testing of sorbent materials. Funding for this program is provided by Environment Canada (EC), Canadian Coast Guard (CCG), Marine Spill Response Corporation (MSRC), US Coast Guard (USCG), and US Minerals Management Service (MMS). The test methods are based upon those defined by the American Society for Testing and Materials and previous test methods developed by Environment Canada for our series of reports entitled Selection Criteria and Laboratory Evaluation of Oil Spill Sorbents. This series, which was started in 1975, encompasses a number of commercially available oil spill sorbents tested with different petroleum products and hydrocarbon solvents. The testing program will categorize the sorbents according to their operating characteristics. The main categories are oil spills on water, oil spills on land, and industrial use. The characteristics to be evaluated with the new test protocols include initial and maximum sorption capacities, water pickup, buoyancy, reuse potential, retention profile, disintegration (material integrity), and ease of application and retrieval. In the near future are plans to incorporate changes to the test that would involve increasing the list of test liquids to encompass spills in an industrial setting, in addition to testing sorbent booms and addressing the disposal problem

  7. Impact of Laboratory Test Use Strategies in a Turkish Hospital.

    Directory of Open Access Journals (Sweden)

    Fatma Meriç Yılmaz

    Full Text Available Eliminating unnecessary laboratory tests is a good way to reduce costs while maintain patient safety. The aim of this study was to define and process strategies to rationalize laboratory use in Ankara Numune Training and Research Hospital (ANH and calculate potential savings in costs.A collaborative plan was defined by hospital managers; joint meetings with ANHTA and laboratory professors were set; the joint committee invited relevant staff for input, and a laboratory efficiency committee was created. Literature was reviewed systematically to identify strategies used to improve laboratory efficiency. Strategies that would be applicable in local settings were identified for implementation, processed, and the impact on clinical use and costs assessed for 12 months.Laboratory use in ANH differed enormously among clinics. Major use was identified in internal medicine. The mean number of tests per patient was 15.8. Unnecessary testing for chloride, folic acid, free prostate specific antigen, hepatitis and HIV testing were observed. Test panel use was pinpointed as the main cause of overuse of the laboratory and the Hospital Information System test ordering page was reorganized. A significant decrease (between 12.6-85.0% was observed for the tests that were taken to an alternative page on the computer screen. The one year study saving was equivalent to 371,183 US dollars.Hospital-based committees including laboratory professionals and clinicians can define hospital based problems and led to a standardized approach to test use that can help clinicians reduce laboratory costs through appropriate use of laboratory tests.

  8. Benefits of a Pharmacology Antimalarial Reference Standard and Proficiency Testing Program Provided by the Worldwide Antimalarial Resistance Network (WWARN)

    Science.gov (United States)

    Lourens, Chris; Lindegardh, Niklas; Barnes, Karen I.; Guerin, Philippe J.; Sibley, Carol H.; White, Nicholas J.

    2014-01-01

    Comprehensive assessment of antimalarial drug resistance should include measurements of antimalarial blood or plasma concentrations in clinical trials and in individual assessments of treatment failure so that true resistance can be differentiated from inadequate drug exposure. Pharmacometric modeling is necessary to assess pharmacokinetic-pharmacodynamic relationships in different populations to optimize dosing. To accomplish both effectively and to allow comparison of data from different laboratories, it is essential that drug concentration measurement is accurate. Proficiency testing (PT) of laboratory procedures is necessary for verification of assay results. Within the Worldwide Antimalarial Resistance Network (WWARN), the goal of the quality assurance/quality control (QA/QC) program is to facilitate and sustain high-quality antimalarial assays. The QA/QC program consists of an international PT program for pharmacology laboratories and a reference material (RM) program for the provision of antimalarial drug standards, metabolites, and internal standards for laboratory use. The RM program currently distributes accurately weighed quantities of antimalarial drug standards, metabolites, and internal standards to 44 pharmacology, in vitro, and drug quality testing laboratories. The pharmacology PT program has sent samples to eight laboratories in four rounds of testing. WWARN technical experts have provided advice for correcting identified problems to improve performance of subsequent analysis and ultimately improved the quality of data. Many participants have demonstrated substantial improvements over subsequent rounds of PT. The WWARN QA/QC program has improved the quality and value of antimalarial drug measurement in laboratories globally. It is a model that has potential to be applied to strengthening laboratories more widely and improving the therapeutics of other infectious diseases. PMID:24777099

  9. Influence of diet on the results of laboratory tests

    Directory of Open Access Journals (Sweden)

    Kinga Lis

    2013-12-01

    Full Text Available Blood and urine laboratory tests are necessary to diagnose the state of the patient. These tests are also helpful in the assessment of diet and nutritional status of the organism. It is recommended that both blood and urine for laboratory tests be collected in the morning, from fasting patients after an overnight rest. These conditions are defined as the standard conditions for collection of material for laboratory testing. Before testing, patients should follow their natural diet and avoid physical exertion, night work, long-distance travel, as well as consumption of alcohol and drugs. They should also reduce the consumption of synthetic vitamins and herbal remedies and other dietary supplements. Medications should be limited to those that are absolutely necessary. All of these factors can affect the results of laboratory tests.

  10. The Computerized Laboratory Notebook concept for genetic toxicology experimentation and testing.

    Science.gov (United States)

    Strauss, G H; Stanford, W L; Berkowitz, S J

    1989-03-01

    We describe a microcomputer system utilizing the Computerized Laboratory Notebook (CLN) concept developed in our laboratory for the purpose of automating the Battery of Leukocyte Tests (BLT). The BLT was designed to evaluate blood specimens for toxic, immunotoxic, and genotoxic effects after in vivo exposure to putative mutagens. A system was developed with the advantages of low cost, limited spatial requirements, ease of use for personnel inexperienced with computers, and applicability to specific testing yet flexibility for experimentation. This system eliminates cumbersome record keeping and repetitive analysis inherent in genetic toxicology bioassays. Statistical analysis of the vast quantity of data produced by the BLT would not be feasible without a central database. Our central database is maintained by an integrated package which we have adapted to develop the CLN. The clonal assay of lymphocyte mutagenesis (CALM) section of the CLN is demonstrated. PC-Slaves expand the microcomputer to multiple workstations so that our computerized notebook can be used next to a hood while other work is done in an office and instrument room simultaneously. Communication with peripheral instruments is an indispensable part of many laboratory operations, and we present a representative program, written to acquire and analyze CALM data, for communicating with both a liquid scintillation counter and an ELISA plate reader. In conclusion we discuss how our computer system could easily be adapted to the needs of other laboratories.

  11. Point-of-Care Test Equipment for Flexible Laboratory Automation.

    Science.gov (United States)

    You, Won Suk; Park, Jae Jun; Jin, Sung Moon; Ryew, Sung Moo; Choi, Hyouk Ryeol

    2014-08-01

    Blood tests are some of the core clinical laboratory tests for diagnosing patients. In hospitals, an automated process called total laboratory automation, which relies on a set of sophisticated equipment, is normally adopted for blood tests. Noting that the total laboratory automation system typically requires a large footprint and significant amount of power, slim and easy-to-move blood test equipment is necessary for specific demands such as emergency departments or small-size local clinics. In this article, we present a point-of-care test system that can provide flexibility and portability with low cost. First, the system components, including a reagent tray, dispensing module, microfluidic disk rotor, and photometry scanner, and their functions are explained. Then, a scheduler algorithm to provide a point-of-care test platform with an efficient test schedule to reduce test time is introduced. Finally, the results of diagnostic tests are presented to evaluate the system. © 2014 Society for Laboratory Automation and Screening.

  12. Argonne National Laboratory annual report of Laboratory Directed Research and Development Program Activities FY 2009.

    Energy Technology Data Exchange (ETDEWEB)

    Office of the Director

    2010-04-09

    I am pleased to submit Argonne National Laboratory's Annual Report on its Laboratory Directed Research and Development (LDRD) activities for fiscal year 2009. Fiscal year 2009 saw a heightened focus by DOE and the nation on the need to develop new sources of energy. Argonne scientists are investigating many different sources of energy, including nuclear, solar, and biofuels, as well as ways to store, use, and transmit energy more safely, cleanly, and efficiently. DOE selected Argonne as the site for two new Energy Frontier Research Centers (EFRCs) - the Institute for Atom-Efficient Chemical Transformations and the Center for Electrical Energy Storage - and funded two other EFRCs to which Argonne is a major partner. The award of at least two of the EFRCs can be directly linked to early LDRD-funded efforts. LDRD has historically seeded important programs and facilities at the lab. Two of these facilities, the Advanced Photon Source and the Center for Nanoscale Materials, are now vital contributors to today's LDRD Program. New and enhanced capabilities, many of which relied on LDRD in their early stages, now help the laboratory pursue its evolving strategic goals. LDRD has, since its inception, been an invaluable resource for positioning the Laboratory to anticipate, and thus be prepared to contribute to, the future science and technology needs of DOE and the nation. During times of change, LDRD becomes all the more vital for facilitating the necessary adjustments while maintaining and enhancing the capabilities of our staff and facilities. Although I am new to the role of Laboratory Director, my immediate prior service as Deputy Laboratory Director for Programs afforded me continuous involvement in the LDRD program and its management. Therefore, I can attest that Argonne's program adhered closely to the requirements of DOE Order 413.2b and associated guidelines governing LDRD. Our LDRD program management continually strives to be more efficient. In

  13. Argonne National Laboratory annual report of Laboratory Directed Research and Development Program Activities FY 2009

    International Nuclear Information System (INIS)

    2010-01-01

    I am pleased to submit Argonne National Laboratory's Annual Report on its Laboratory Directed Research and Development (LDRD) activities for fiscal year 2009. Fiscal year 2009 saw a heightened focus by DOE and the nation on the need to develop new sources of energy. Argonne scientists are investigating many different sources of energy, including nuclear, solar, and biofuels, as well as ways to store, use, and transmit energy more safely, cleanly, and efficiently. DOE selected Argonne as the site for two new Energy Frontier Research Centers (EFRCs) - the Institute for Atom-Efficient Chemical Transformations and the Center for Electrical Energy Storage - and funded two other EFRCs to which Argonne is a major partner. The award of at least two of the EFRCs can be directly linked to early LDRD-funded efforts. LDRD has historically seeded important programs and facilities at the lab. Two of these facilities, the Advanced Photon Source and the Center for Nanoscale Materials, are now vital contributors to today's LDRD Program. New and enhanced capabilities, many of which relied on LDRD in their early stages, now help the laboratory pursue its evolving strategic goals. LDRD has, since its inception, been an invaluable resource for positioning the Laboratory to anticipate, and thus be prepared to contribute to, the future science and technology needs of DOE and the nation. During times of change, LDRD becomes all the more vital for facilitating the necessary adjustments while maintaining and enhancing the capabilities of our staff and facilities. Although I am new to the role of Laboratory Director, my immediate prior service as Deputy Laboratory Director for Programs afforded me continuous involvement in the LDRD program and its management. Therefore, I can attest that Argonne's program adhered closely to the requirements of DOE Order 413.2b and associated guidelines governing LDRD. Our LDRD program management continually strives to be more efficient. In addition to

  14. LABORATORY DIRECTED RESEARCH AND DEVELOPMENT PROGRAM ACTIVITIES FOR FY2002.

    Energy Technology Data Exchange (ETDEWEB)

    FOX,K.J.

    2002-12-31

    Brookhaven National (BNL) Laboratory is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, under contract with the U. S. Department of Energy. BNL's total annual budget has averaged about $450 million. There are about 3,000 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 4 1 3.2A, ''Laboratory Directed Research and Development,'' January 8, 2001, and the LDRD Annual Report guidance, updated February 12, 1999. The LDRD Program obtains its funds through the Laboratory overhead pool and operates under the authority of DOE Order 413.2A. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new ''fundable'' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research ''which could lead to new programs, projects, and directions'' for the Laboratory. As one of the premier scientific laboratories of the DOE, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its LDRD Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community and foster new science and technology

  15. Acoustic testing and modeling: an advanced undergraduate laboratory.

    Science.gov (United States)

    Russell, Daniel A; Ludwigsen, Daniel O

    2012-03-01

    This paper describes an advanced laboratory course in acoustics, specifically targeted for students with an interest in engineering applications at a school with a strongly integrated industrial co-op program. The laboratory course is developed around a three-pronged approach to problem solving that combines and integrates theoretical models, computational models, and experimental data. The course is structured around modules that begin with fundamental concepts and build laboratory skills and expand the knowledge base toward a final project. Students keep a detailed laboratory notebook, write research papers in teams, and must pass laboratory certification exams. This paper describes the course layout and philosophy and shares personal experience from both faculty and student perspectives. © 2012 Acoustical Society of America

  16. Laboratory evaluation of immunochromatographic rapid diagnostic tests for cholera in Haiti.

    Directory of Open Access Journals (Sweden)

    Wilfredo R Matias

    Full Text Available Rapid diagnostic tests (RDT for cholera are promising tools for detecting cholera in areas with limited laboratory infrastructure. However, evidence on the characteristics of the many available RDTs is scarce, and their use has been limited by suboptimal performance. We evaluated the performance characteristics of three cholera RDTs from Span Diagnostics, Artron Laboratories, and Standard Diagnostics in a regional laboratory in Haiti.We retrospectively reviewed records from May 2014 to October 2015 of a laboratory-based surveillance program for Vibrio cholerae at Hôpital Saint-Nicolas in Saint-Marc, Haiti. We compared the results of 511 Crystal VC, 129 Artron and 451 SD Bioline RDTs to bacterial culture as the gold standard. Of 905 cultures, 477 (52.7% were positive for V. cholerae O1, of which 27.7% were serotype Inaba. No cultures grew V. cholerae O139. Sensitivity and specificity of Crystal VC were 98.6% (95%CI: 96.5%-99.6% and 71.1% (95%CI: 64.7%-76.9%, respectively. Artron demonstrated a sensitivity of 98.6% (95%CI: 92.7%-100% and specificity of 69.1% (95%CI: 55.2%-80.9%. SD Bioline demonstrated a sensitivity of 81.1% (95%CI: 75.6%-85.8% and specificity of 92.8% (95%CI: 88.4%-95.9%. Crystal VC and Artron frequently showed false positive O139 bands, whereas none were seen with SD Bioline.There is significant variation in the performance of different cholera diagnostic RDTs. Artron and Crystal VC RDTs have high sensitivity and low specificity, while SD Bioline RDT has low to moderate sensitivity and high specificity when performed by laboratory technicians in Haiti. Study limitations included its retrospective design. The suboptimal characteristics of these tests limit their use as clinical point-of-care tests; however, they may be useful in outbreak response, surveillance, and research in resource-limited settings.

  17. Iowa Central Quality Fuel Testing Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Heach, Don; Bidieman, Julaine

    2013-09-30

    The objective of this project is to finalize the creation of an independent quality fuel testing laboratory on the campus of Iowa Central Community College in Fort Dodge, Iowa that shall provide the exploding biofuels industry a timely and cost-effective centrally located laboratory to complete all state and federal fuel and related tests that are required. The recipient shall work with various state regulatory agencies, biofuel companies and state and national industry associations to ensure that training and testing needs of their members and American consumers are met. The recipient shall work with the Iowa Department of Ag and Land Stewardship on the development of an Iowa Biofuel Quality Standard along with the Development of a standard that can be used throughout industry.

  18. Laboratory performance testing of an extruded bitumen containing a surrogate, sodium nitrate-based, low-level aqueous waste

    International Nuclear Information System (INIS)

    Mattus, A.J.; Kaczmarsky, M.M.

    1986-01-01

    Laboratory results of a comprehensive, regulatory performance test program, utilizing an extruded bitumen and a surrogate, sodium nitrate-based waste, have been compiled at the Oak Ridge National Laboratory (ORNL). Using a 53 millimeter, Werner and Pfleiderer extruder, operated by personnel of WasteChem Corporation of Paramus, New Jersey, laboratory-scale, molded samples of type three, air blown bitumen were prepared for laboratory performance testing. A surrogate, low-level, mixed liquid waste, formulated to represent an actual on-site waste at ORNL, containing about 30 wt % sodium nitrate, in addition to eight heavy metals, cold cesium and strontium was utilized. Samples tested contained three levels of waste loading: that is, forty, fifty and sixty wt % salt. Performance test results include the ninety day ANS 16.1 leach test, with leach indices reported for all cations and anions, in addition to the EP Toxicity test, at all levels of waste loading. Additionally, test results presented also include the unconfined compressive strength and surface morphology utilizing scanning electron microscopy. Data presented include correlations between waste form loading and test results, in addition to their relationship to regulatory performance requirements

  19. Test plan for ISV laboratory-pyrolysis testing

    Energy Technology Data Exchange (ETDEWEB)

    McAtee, R.E.

    1991-09-01

    The objective of the laboratory-pyrolysis studies is to obtain information on the high temperature (< 1200{degree}C) degradation and alteration of organic chemicals and materials similar to those found in the Radioactive Waste Management Complex, Pit 9. This test plan describes experimental procedures, sampling and analysis strategy, sampling procedures, sample control, and document management. It addresses safety issues in the experimental apparatus and procedures, personal training, and hazardous waste disposal. Finally, it describes the data quality objectives using the EPA tiered approach to treatability studies to define where research/scoping tests fit into these studies and the EPA analytical levels required for the tests.

  20. Rockwell International's Critical Mass Laboratory Program at the Rocky Flats Plant

    International Nuclear Information System (INIS)

    McCarthy, J.D.

    1984-01-01

    The primary mission of the laboratory is to provide data in support of plant operations. To fulfill this task, the facility has unique capabilities for perfoming general purpose critical mass experiment. The critical mass laboratory performed over 1000 critical measurements, primarily with plutonium metal and uranium metal, oxide and solution; it worked also on the NRC program (high-enriched uranium measurements). Presently the laboratory staff prepares for a series of critical measurements on a poisoned tube tank; the laboratory intends to continue to pursue basic plant support programs in the future

  1. Manual on laboratory testing for uranium ore processing

    International Nuclear Information System (INIS)

    1990-01-01

    Laboratory testing of uranium ores is an essential step in the economic evaluation of uranium occurrences and in the development of a project for the production of uranium concentrates. Although these tests represent only a small proportion of the total cost of a project, their proper planning, execution and interpretation are of crucial importance. The main purposes of this manual are to discuss the objectives of metallurgical laboratory ore testing, to show the specific role of these tests in the development of a project, and to provide practical instructions for performing the tests and for interpreting their results. Guidelines on the design of a metallurgical laboratory, on the equipment required to perform the tests and on laboratory safety are also given. This manual is part of a series of Technical Reports on uranium ore processing being prepared by the IAEA's Division of Nuclear Fuel Cycle and Waste Management. A report on the Significance of Mineralogy in the Development of Flowsheets for Processing Uranium Ores (Technical Reports Series No. 196, 1980) and an instruction manual on Methods for the Estimation of Uranium Ore Reserves (No. 255, 1985) have already been published. 17 refs, 40 figs, 17 tabs

  2. Sandia National Laboratories, California Environmental Management System program manual.

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, Barbara L.

    2013-04-01

    The Sandia National Laboratories, California (SNL/CA) Environmental Management System (EMS) Program Manual documents the elements of the site EMS Program. The SNL/CA EMS Program conforms to the International Standard on Environmental Management Systems, ISO 14001:2004 and Department of Energy (DOE) Order 436.1.

  3. Sandia National Laboratories, California Environmental Management System program manual

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, Barbara L.

    2014-04-01

    The Sandia National Laboratories, California (SNL/CA) Environmental Management System (EMS) Program Manual documents the elements of the site EMS Program. The SNL/CA EMS Program conforms to the International Standard on Environmental Management Systems, ISO 14001:2004 and Department of Energy (DOE) Order 436.1.

  4. Educational digital resource for data analysis of Civil Engineering laboratory tests

    Directory of Open Access Journals (Sweden)

    Gustavo Henrique Nalon

    2018-02-01

    Full Text Available This work aims to implement and evaluate an interactive educational software that helps Civil Engineering students to perform and analyze the calculations related to different Soil Mechanics laboratory tests. This experience consists of an attempt to incorporate information and communication technologies (ICTs into the engineering teaching-learning process. The content of the program is distributed into three different modules: “Compaction test”, “Consolidation test”, and “Direct shear test”. Using vector graphics, tables, illustrative figures, animations, equations, tip buttons, and immediate correction of mistakes, the software clarifies the relationship between theoretical concepts and practical laboratory results, instructs the students in the moments of doubt, attracts their interest, and motivates them to achieve the complete data interpretation. Based on the results of an applied evaluation questionnaire, it was observed that most of the students were satisfied with the contents and functionalities of the program. The developed tool can be an inspiration for the creation of new educational software that improve the quality of education in different engineering areas.

  5. Sandia National Laboratories, California Waste Management Program annual report.

    Energy Technology Data Exchange (ETDEWEB)

    Brynildson, Mark E.

    2010-02-01

    The annual program report provides detailed information about all aspects of the Sandia National Laboratories, California (SNL/CA) Waste Management Program. It functions as supporting documentation to the SNL/CA Environmental Management System Program Manual. This annual program report describes the activities undertaken during the past year, and activities planned in future years to implement the Waste Management (WM) Program, one of six programs that supports environmental management at SNL/CA.

  6. A measurement evaluation program to support nuclear material control and accountability measurements in Brazilian laboratories

    International Nuclear Information System (INIS)

    Dias, Fabio C.; Mason, Peter

    2013-01-01

    A measurement evaluation program (MEP) is one of a number of valuable tools that analytical chemists can use to ensure that the data produced in the laboratory are fit for their intended purpose and consistent with expected performance values at a given time. As such, participation in a MEP is an important indicator of the quality of analytical data, and is recognized as such by independent regulatory and/or accreditation bodies. With the intent to implement such a program in Brazil, in November 2012 the Nuclear Energy Commission of Brazil (CNEN), with support from the Department of Energy of the United States' (US-DOE International Safeguards and Engagement Program), decided to initiate a technical cooperation project aiming at organizing a Safeguards Measurement Evaluation Program (SMEP) for Brazilian facilities. The project, entitled Action Sheet 23, was formalized under the terms of the Agreement between the US-DOE and the CNEN concerning research and development in nuclear material control, accountancy, verification, physical protection, and advanced containment and surveillance technologies for International Safeguards Applications. The work, jointly performed by the CNEN's Safeguards Laboratory (LASAL) and the New Brunswick Laboratory (NBL), has the objective to strengthen the traceability of accountability measurements and ensure adequate quality of safeguards measurements for facilities within Brazil, utilizing test samples characterized and provided by NBL. Recommendations to participants included measurement frequency, number of results per sample and format for reporting results using ISO methods for calculating and expressing measurement uncertainties. In this paper, we discuss the main steps taken by CNEN and NBL aiming at implementing such a program and the expected results, in particular the impact of uncertainty estimation on the evaluation of performance of each participant laboratory. The program is considered by Brazilian safeguards authorities

  7. A measurement evaluation program to support nuclear material control and accountability measurements in Brazilian laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Dias, Fabio C., E-mail: fabio@ird.gov.br [Comissao Nacional de Energia Nuclear (CNEN-RJ), Rio de Janeiro, RJ (Brazil); Mason, Peter, E-mail: peter.mason@ch.doe.gov [New Brunswick Laboratory (DOE/NBL), Argonne, IL (United States)

    2013-07-01

    A measurement evaluation program (MEP) is one of a number of valuable tools that analytical chemists can use to ensure that the data produced in the laboratory are fit for their intended purpose and consistent with expected performance values at a given time. As such, participation in a MEP is an important indicator of the quality of analytical data, and is recognized as such by independent regulatory and/or accreditation bodies. With the intent to implement such a program in Brazil, in November 2012 the Nuclear Energy Commission of Brazil (CNEN), with support from the Department of Energy of the United States' (US-DOE International Safeguards and Engagement Program), decided to initiate a technical cooperation project aiming at organizing a Safeguards Measurement Evaluation Program (SMEP) for Brazilian facilities. The project, entitled Action Sheet 23, was formalized under the terms of the Agreement between the US-DOE and the CNEN concerning research and development in nuclear material control, accountancy, verification, physical protection, and advanced containment and surveillance technologies for International Safeguards Applications. The work, jointly performed by the CNEN's Safeguards Laboratory (LASAL) and the New Brunswick Laboratory (NBL), has the objective to strengthen the traceability of accountability measurements and ensure adequate quality of safeguards measurements for facilities within Brazil, utilizing test samples characterized and provided by NBL. Recommendations to participants included measurement frequency, number of results per sample and format for reporting results using ISO methods for calculating and expressing measurement uncertainties. In this paper, we discuss the main steps taken by CNEN and NBL aiming at implementing such a program and the expected results, in particular the impact of uncertainty estimation on the evaluation of performance of each participant laboratory. The program is considered by Brazilian safeguards

  8. Spacecraft contamination programs within the Air Force Systems Command Laboratories

    Science.gov (United States)

    Murad, Edmond

    1990-01-01

    Spacecraft contamination programs exist in five independent AFSC organizations: Geophysics Laboratory (GL), Arnold Engineering and Development Center (AEDC), Rome Air Development Center (RADC/OSCE), Wright Research and Development Center (MLBT), Armament Laboratory (ATL/SAI), and Space Systems Division (SSD/OL-AW). In addition, a sizable program exists at Aerospace Corp. These programs are complementary, each effort addressing a specific area of expertise: GL's effort is aimed at addressing the effects of on-orbit contamination; AEDC's effort is aimed at ground simulation and measurement of optical contamination; RADC's effort addresses the accumulation, measurement, and removal of contamination on large optics; MLBT's effort is aimed at understanding the effect of contamination on materials; ATL's effort is aimed at understanding the effect of plume contamination on systems; SSD's effort is confined to the integration of some contamination experiments sponsored by SSD/CLT; and Aerospace Corp.'s effort is aimed at supporting the needs of the using System Program Offices (SPO) in specific areas, such as contamination during ground handling, ascent phase, laboratory measurements aimed at understanding on-orbit contamination, and mass loss and mass gain in on-orbit operations. These programs are described in some detail, with emphasis on GL's program.

  9. Centrifugal contractors for laboratory-scale solvent extraction tests

    International Nuclear Information System (INIS)

    Leonard, R.A.; Chamberlain, D.B.; Conner, C.

    1995-01-01

    A 2-cm contactor (minicontactor) was developed and used at Argonne National Laboratory for laboratory-scale testing of solvent extraction flowsheets. This new contactor requires only 1 L of simulated waste feed, which is significantly less than the 10 L required for the 4-cm unit that had previously been used. In addition, the volume requirements for the other aqueous and organic feeds are reduced correspondingly. This paper (1) discusses the design of the minicontactor, (2) describes results from having applied the minicontactor to testing various solvent extraction flowsheets, and (3) compares the minicontactor with the 4-cm contactor as a device for testing solvent extraction flowsheets on a laboratory scale

  10. 19 CFR 151.54 - Testing by Customs laboratory.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Testing by Customs laboratory. 151.54 Section 151.54 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF... Other Metal-Bearing Materials § 151.54 Testing by Customs laboratory. Samples taken in accordance with...

  11. The role of the EPA radiation quality assurance program in the measurement quality assurance accreditation program for radioassay laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Grady, T.M. [Environmental Monitoring Systems Laboratory, Las Vegas, NV (United States)

    1993-12-31

    As the nature and extent of radiological contamination becomes better documented and more public, radioanalytical laboratories are faced with a constantly expanding variety of new and difficult analytical requirements. Concurrent with those requirements is the responsibility to provide customers, regulatory officials, or the public with defensible data produced in an environment of verifiable, controlled quality. To meet that need, a quality assurance accreditation program for radioassay laboratories has been proposed by the American National Standards Institute (ANSI). The standard will provide the organizational framework and functional requirements needed to assure the quality of laboratory outputs. Under the proposed program, the U.S. Environmental Protection Agency`s (EPA`s) Laboratory Intercomparison Program plays a key role as a reference laboratory. The current and proposed roles of the EPA Intercomparison Program are discussed, as are the functional relationships between EPA, the accreditating organization, and the service and monitoring laboratories.

  12. Laboratory directed research and development. FY 1991 program activities: Summary report

    Energy Technology Data Exchange (ETDEWEB)

    1991-11-15

    The purposes of Argonne`s Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel concepts, enhance the Laboratory`s R&D capabilities, and further the development of its strategic initiatives. Among the aims of the projects supported by the Program are establishment of engineering ``proof-of-principle``; development of an instrumental prototype, method, or system; or discovery in fundamental science. Several of these project are closely associated with major strategic thrusts of the Laboratory as described in Argonne`s Five Year Institutional Plan, although the scientific implications of the achieved results extend well beyond Laboratory plans and objectives. The projects supported by the Program are distributed across the major programmatic areas at Argonne. Areas of emphasis are (1) advanced accelerator and detector technology, (2) x-ray techniques in biological and physical sciences, (3) advanced reactor technology, (4) materials science, computational science, biological sciences and environmental sciences. Individual reports summarizing the purpose, approach, and results of projects are presented.

  13. Pipe damping: experimental results from laboratory tests in the seismic frequency range

    International Nuclear Information System (INIS)

    Ware, A.G.; Arendts, J.G.

    1986-06-01

    The Idaho National Engineering Laboratory (INEL) has been conducting a research program to assist the United States Nuclear Regulatory Commission (USNRC) in determining best-estimate damping values for the seismic analysis of nuclear piping systems. As part of this program, a 5-in. piping system was tested by the INEL, and data from USNRC/EPRI piping vibration tests at the ANCO Engineers facility were evaluated. These systems were subjected to various types of excitation methods and magnitudes, the support configurations were varied, and the effects of pipe insulation and internal pressure were investigated on the INEL system. The INEL has used several different methods to reduce the data to determine the damping in both these piping systems under the various test conditions. It was concluded that at representative seismic excitation levels, pressure was not a contributing factor, but the supports, insulation, and magnitude of response all were major influences contributing to damping. These tests are part of the ongoing program to determine how various parameters and data reduction methods affect piping system damping. The evaluation of all relevant test results, including these two series, will potentially lead to revised damping guidelines for the seismic analysis of nuclear plants, making them safer, less costly, and easier to inspect and maintain. The test results as well as accompanying evaluations and recommendations are presented in this report. 27 refs., 72 figs., 13 tabs

  14. NNSA Laboratory Directed Research and Development Program 2008 Symposium--Focus on Energy Security

    Energy Technology Data Exchange (ETDEWEB)

    Kotta, P R; Sketchley, J A

    2008-08-20

    sequestration, energy efficiency, and other energy security research projects that are being conducted under the LDRD Program at the DOE/NNSA national laboratories and under the Site Directed Research and Development Program (SDRD) at the Nevada Test Site. Speakers from DOE/NNSA, other federal agencies, the NNSA laboratories, and the private sector will provide their insights into the national security implications of emerging energy and environmental issues, and the LDRD investments in energy security at the national laboratories. Please take this opportunity to reflect upon the science and engineering needs of our country's energy demands, including those issues posed by climate change, paying attention to the innovative contributions that LDRD is providing to the nation.

  15. Environmental Measurements Laboratory program review, December 1983

    International Nuclear Information System (INIS)

    Volchok, H.L.; de Planque, G.

    1984-03-01

    This volume contains all of the written material that was submitted to the panel of Reviewers in advance of a Program Review conducted by the US Department of Energy, Office of Health and Environmental Research at the Environmental Measurements Laboratory (EML) December 7-9, 1983. In addition to a general introduction there are nineteen papers grouped into the five broad program categories covering all of the scientific and engineering projects of the Laboratory: Natural Radioactivity and Radiation, Anthropogenic Radioactivity and Radiation, Non-nuclear, Quality Assurance, and Development and Support. These short articles, for the most part, focus on the rationale for EML's involvement in each project, emphasizing their relevance to the EML and Department of Energy missions. Project results and their interpretation were presented at the Review and can be found in the material referenced in this volume

  16. Argonne National Laboratory Annual Report of Laboratory Directed Research and Development Program Activities for FY 1994

    Energy Technology Data Exchange (ETDEWEB)

    None

    1995-02-25

    The purposes of Argonne's Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel concepts, enhance the Laboratory's R and D capabilities, and further the development of its strategic initiatives. Projects are selected from proposals for creative and innovative R and D studies which are not yet eligible for timely support through normal programmatic channels. Among the aims of the projects supported by the Program are establishment of engineering proof-of-principle; assessment of design feasibility for prospective facilities; development of an instrumental prototype, method, or system; or discovery in fundamental science. Several of these projects are closely associated with major strategic thrusts of the Laboratory as described in Argonne's Five-Year Institutional Plan, although the scientific implications of the achieved results extend well beyond Laboratory plans and objectives. The projects supported by the Program are distributed across the major programmatic areas at Argonne as indicated in the Laboratory's LDRD Plan for FY 1994. Project summaries of research in the following areas are included: (1) Advanced Accelerator and Detector Technology; (2) X-ray Techniques for Research in Biological and Physical Science; (3) Nuclear Technology; (4) Materials Science and Technology; (5) Computational Science and Technology; (6) Biological Sciences; (7) Environmental Sciences: (8) Environmental Control and Waste Management Technology; and (9) Novel Concepts in Other Areas.

  17. Hydrologic resources management program and underground test area operable unit fy 1997

    Energy Technology Data Exchange (ETDEWEB)

    Smith, D. F., LLNL

    1998-05-01

    This report present the results of FY 1997 technical studies conducted by the Lawrence Livermore National Laboratory (LLNL) as part of the Hydrology and Radionuclide Migration Program (HRMP) and Underground Test Area Operable Unit (UGTA). The HRMP is sponsored by the US Department of Energy to assess the environmental (radiochemical and hydrologic) consequences of underground nuclear weapons testing at the Nevada Test Site.

  18. Technical requirements for the actinide source-term waste test program

    Energy Technology Data Exchange (ETDEWEB)

    Phillips, M.L.F.; Molecke, M.A.

    1993-10-01

    This document defines the technical requirements for a test program designed to measure time-dependent concentrations of actinide elements from contact-handled transuranic (CH TRU) waste immersed in brines similar to those found in the underground workings of the Waste Isolation Pilot Plant (WIPP). This test program wig determine the influences of TRU waste constituents on the concentrations of dissolved and suspended actinides relevant to the performance of the WIPP. These influences (which include pH, Eh, complexing agents, sorbent phases, and colloidal particles) can affect solubilities and colloidal mobilization of actinides. The test concept involves fully inundating several TRU waste types with simulated WIPP brines in sealed containers and monitoring the concentrations of actinide species in the leachate as a function of time. The results from this program will be used to test numeric models of actinide concentrations derived from laboratory studies. The model is required for WIPP performance assessment with respect to the Environmental Protection Agency`s 40 CFR Part 191B.

  19. Technical requirements for the actinide source-term waste test program

    International Nuclear Information System (INIS)

    Phillips, M.L.F.; Molecke, M.A.

    1993-10-01

    This document defines the technical requirements for a test program designed to measure time-dependent concentrations of actinide elements from contact-handled transuranic (CH TRU) waste immersed in brines similar to those found in the underground workings of the Waste Isolation Pilot Plant (WIPP). This test program wig determine the influences of TRU waste constituents on the concentrations of dissolved and suspended actinides relevant to the performance of the WIPP. These influences (which include pH, Eh, complexing agents, sorbent phases, and colloidal particles) can affect solubilities and colloidal mobilization of actinides. The test concept involves fully inundating several TRU waste types with simulated WIPP brines in sealed containers and monitoring the concentrations of actinide species in the leachate as a function of time. The results from this program will be used to test numeric models of actinide concentrations derived from laboratory studies. The model is required for WIPP performance assessment with respect to the Environmental Protection Agency's 40 CFR Part 191B

  20. 2016 Annual Site Environmental report Sandia National Laboratories Tonopah Test Range Nevada & Kaua'i Test Facility Hawai'i.

    Energy Technology Data Exchange (ETDEWEB)

    Salas, Angela Maria [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Griffith, Stacy R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-07-01

    Sandia National Laboratories (SNL) is a multimission laboratory managed and operated by National Technology & Engineering Solutions of Sandia, LLC, a wholly owned subsidiary of Honeywell International Inc., for the U.S. Department of Energy’s (DOE’s), National Nuclear Security Administration (NNSA) under contract DE-NA0003525. The DOE/NNSA Sandia Field Office administers the contract and oversees contractor operations at the SNL, Tonopah Test Range (SNL/TTR) in Nevada and the SNL, Kaua‘i Test Facility (SNL/KTF) in Hawai‘i. SNL personnel manage and conduct operations at SNL/TTR in support of the DOE/NNSA’s Weapons Ordnance Program and have operated the site since 1957. Navarro Research and Engineering personnel perform most of the environmental programs activities at SNL/TTR. The DOE/NNSA/Nevada Field Office retains responsibility for cleanup and management of SNL/TTR Environmental Restoration sites. SNL personnel operate SNL/KTF as a rocket preparation launching and tracking facility. This Annual Site Environmental Report (ASER) summarizes data and the compliance status of sustainability, environmental protection, and monitoring programs at SNL/TTR and SNL/KTF during calendar year 2016. Major environmental programs include air quality, water quality, groundwater protection, terrestrial and biological surveillance, waste management, pollution prevention, environmental restoration, oil and chemical spill prevention, and implementation of the National Environmental Policy Act. This ASER is prepared in accordance with and as required by DOE O 231.1B, Admin Change 1, Environment, Safety, and Health Reporting.

  1. [Standardization in laboratory hematology by participating in external quality assurance programs].

    Science.gov (United States)

    Nazor, Aida; Siftar, Zoran; Flegar-Mestrić, Zlata

    2011-09-01

    Since 1985, Department of Clinical Chemistry and Laboratory Medicine, Merkur University Hospital, Zagreb, has been participating in the International External Quality Assessment Scheme for Hematology (IEQAS-H) organized by the World Health Organization (WHO). Owing to very good results, in 1987 the Department received a certificate of participation in this control scheme. Department has been cooperating in the external quality assessment program in laboratory hematology which has been continuously performed in Croatia since 1986 by the Committee for External Quality Assessment Schemes under the auspices of the Croatian Society of Medical Biochemists and School of Pharmacy and Biochemistry, University of Zagreb. Nowadays, 186 medical biochemical laboratories are included in the National External Quality Assessment program, which is performed three times per year. Our Department has participated in the international projects of the European Committee for External Quality Assurance Programs in Laboratory Medicine (EQALM).

  2. Improvement of the quality control program of the clinical dosimeters calibration laboratory of the IPEN/CNEN-SP

    Energy Technology Data Exchange (ETDEWEB)

    Damatto, Willian B.; Potiens, Maria da Penha A.; Vivolo, Vitor, E-mail: wbdamatto@ipen.br, E-mail: mppotiens@ipen.br, E-mail: vivolo@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2013-07-01

    A set of clinical dosimeters (thimble ionization chamber coupled to an electrometer) commonly used in radiotherapy in Brazil and sent to the Calibration Laboratory of IPEN were under several tests and analysis parameters for the dosimeters behaviour were established, specifying their sensitivities and operating characteristics. Applied tests were: repeatability, reproducibility and current leakage. Thus it was possible to determine the most common defects found in these equipment and the actions that could be taken to prevent it (clinical dosimeters quality control programs). The behaviour of 167 dosimeters was analyzed and in this study, 62 of them have been tested. The main problem detected during calibration tests was current leakage, i.e. electronic noise. The tests were applied to the routine measurements at the Calibration Laboratory implementing an ideal calibration procedure. New calibration criteria were established following international recommendations. Therefore, it was made the improvement of the quality control programme of the clinical dosimeters calibration laboratory, benefiting the users of such equipment with better consistent calibration measurements. (author)

  3. Improvement of the quality control program of the clinical dosimeters calibration laboratory of the IPEN/CNEN-SP

    International Nuclear Information System (INIS)

    Damatto, Willian B.; Potiens, Maria da Penha A.; Vivolo, Vitor

    2013-01-01

    A set of clinical dosimeters (thimble ionization chamber coupled to an electrometer) commonly used in radiotherapy in Brazil and sent to the Calibration Laboratory of IPEN were under several tests and analysis parameters for the dosimeters behaviour were established, specifying their sensitivities and operating characteristics. Applied tests were: repeatability, reproducibility and current leakage. Thus it was possible to determine the most common defects found in these equipment and the actions that could be taken to prevent it (clinical dosimeters quality control programs). The behaviour of 167 dosimeters was analyzed and in this study, 62 of them have been tested. The main problem detected during calibration tests was current leakage, i.e. electronic noise. The tests were applied to the routine measurements at the Calibration Laboratory implementing an ideal calibration procedure. New calibration criteria were established following international recommendations. Therefore, it was made the improvement of the quality control programme of the clinical dosimeters calibration laboratory, benefiting the users of such equipment with better consistent calibration measurements. (author)

  4. Spent fuel sabotage test program, characterization of aerosol dispersal : interim final report

    International Nuclear Information System (INIS)

    Gregson, Michael Warren; Brockmann, John E.; Loiseau, Olivier; Klennert, Lindsay A.; Nolte, Oliver; Molecke, Martin Alan; Autrusson, Bruno A.; Koch, Wolfgang; Pretzsch, Gunter Guido; Brucher, Wenzel; Steyskal, Michele D.

    2008-01-01

    This multinational, multi-phase spent fuel sabotage test program is quantifying the aerosol particles produced when the products of a high energy density device (HEDD) interact with and explosively particulate test rodlets that contain pellets of either surrogate materials or actual spent fuel. This program provides source-term data that are relevant to plausible sabotage scenarios in relation to spent fuel transport and storage casks and associated risk assessments. We present details and significant results obtained from this program from 2001 through 2007. Measured aerosol results include: respirable fractions produced; amounts, nuclide content, and produced particle size distributions and morphology; measurements of volatile fission product species enhanced sorption--enrichment factors onto respirable particles; and, status on determination of the spent fuel ratio, SFR, needed for scaling studies. Emphasis is provided on recent Phase 3 tests using depleted uranium oxide pellets plus non-radioactive fission product dopants in surrogate spent fuel test rodlets, plus the latest surrogate cerium oxide results and aerosol laboratory supporting calibration work. The DUO 2 , CeO 2 , plus fission product dopant aerosol particle results are compared with available historical data. We also provide a status review on continuing preparations for the final Phase 4 in this program, tests using individual short rodlets containing actual spent fuel from U.S. PWR reactors, with both high- and lower-burnup fuel. The source-term data, aerosol results, and program design have been tailored to support and guide follow-on computer modeling of aerosol dispersal hazards and radiological consequence assessments. This spent fuel sabotage, aerosol test program was performed primarily at Sandia National Laboratories, with support provided by both the U.S. Department of Energy and the Nuclear Regulatory Commission. This program has significant input from, and is cooperatively supported and

  5. Spent fuel sabotage test program, characterization of aerosol dispersal : interim final report.

    Energy Technology Data Exchange (ETDEWEB)

    Gregson, Michael Warren; Brockmann, John E.; Loiseau, Olivier (Institut de Radioprotection et de Surete Nucleaire, France); Klennert, Lindsay A.; Nolte, Oliver (Fraunhofer Institut fur Toxikologie und Experimentelle Medizin, Germany); Molecke, Martin Alan; Autrusson, Bruno A. (Institut de Radioprotection et de Surete Nucleaire, France); Koch, Wolfgang (Fraunhofer Institut fur Toxikologie und Experimentelle Medizin, Germany); Pretzsch, Gunter Guido (Gesellschaft fur Anlagen- und Reaktorsicherheit, Germany); Brucher, Wenzel (Gesellschaft fur Anlagen- und Reaktorsicherheit, Germany); Steyskal, Michele D.

    2008-03-01

    This multinational, multi-phase spent fuel sabotage test program is quantifying the aerosol particles produced when the products of a high energy density device (HEDD) interact with and explosively particulate test rodlets that contain pellets of either surrogate materials or actual spent fuel. This program provides source-term data that are relevant to plausible sabotage scenarios in relation to spent fuel transport and storage casks and associated risk assessments. We present details and significant results obtained from this program from 2001 through 2007. Measured aerosol results include: respirable fractions produced; amounts, nuclide content, and produced particle size distributions and morphology; measurements of volatile fission product species enhanced sorption--enrichment factors onto respirable particles; and, status on determination of the spent fuel ratio, SFR, needed for scaling studies. Emphasis is provided on recent Phase 3 tests using depleted uranium oxide pellets plus non-radioactive fission product dopants in surrogate spent fuel test rodlets, plus the latest surrogate cerium oxide results and aerosol laboratory supporting calibration work. The DUO{sub 2}, CeO{sub 2}, plus fission product dopant aerosol particle results are compared with available historical data. We also provide a status review on continuing preparations for the final Phase 4 in this program, tests using individual short rodlets containing actual spent fuel from U.S. PWR reactors, with both high- and lower-burnup fuel. The source-term data, aerosol results, and program design have been tailored to support and guide follow-on computer modeling of aerosol dispersal hazards and radiological consequence assessments. This spent fuel sabotage, aerosol test program was performed primarily at Sandia National Laboratories, with support provided by both the U.S. Department of Energy and the Nuclear Regulatory Commission. This program has significant input from, and is cooperatively

  6. The planning of future research program of underground laboratories in overseas

    International Nuclear Information System (INIS)

    Honma, Nobuyuki; Tanai, Kenji; Hasegawa, Hiroshi

    2002-02-01

    The objectives of this study is to identify the research issues, which are to be conducted in the future underground research laboratory, about operation and logistics systems for the planning of future research and development program. The research programs and experiments, etc. were investigated for the geological disposal projects in overseas sedimentary rocks and coastal geological environments aiming to reflect in the future underground research facility plan in Japan. In the investigation, information on the engineered-barrier performance, design and construction of underground facilities, tunnel support, transportation and emplacement, and backfilling technology, etc. were collected. Based on these informations, the purpose, the content, and the result of each investigations and tests were arranged. The strategy and the aim in the entire underground research facility, and the flow of investigations and tests, etc. were also arranged from the purpose, the relations and the sequence of each investigation and experiment, and the usage of results, etc. (author)

  7. Technical review of the Sandia Laboratories' Particle Beam Fusion Program

    International Nuclear Information System (INIS)

    1979-01-01

    This report considers the technical aspects of Sandia Laboratories' Particle Beam Fusion Program and examines the program's initial goals, the progress made to date towards reaching those goals, and the future plans or methods of reaching those original or modified goals. A summary of Sandia Laboratories' effort, which seeks to demonstrate that high voltage pulsed power generated high-current electron or light ion beams can be used to ignite a deuterium or tritium pellet, is provided. A brief review and assessment of the Sandia Pulse Power Program is given. Several critical issues and summaries of the committee members' opinions are discussed

  8. Health Physics Society program for accreditation of calibration laboratories

    International Nuclear Information System (INIS)

    West, L.; Masse, F.X.; Swinth, K.L.

    1988-01-01

    The Health Physics Society has instituted a new program for accreditation of organizations that calibrate radiation survey instruments. The purpose of the program is to provide radiation protection professionals with an expanded means of direct and indirect access to national standards, thus introducing a means for improving the uniformity, accuracy, and quality of ionizing radiation field measurements. Secondary accredited laboratories are expected to provide a regional support basis. Tertiary accredited laboratories are expected to operate on a more local basis and provide readily available expertise to end users. The accreditation process is an effort to provide better measurement assurance for surveys of radiation fields. The status of the accreditation program, general criteria, gamma-ray calibration criteria, and x-ray calibration criteria are reviewed

  9. The High Level Vibration Test Program

    International Nuclear Information System (INIS)

    Hofmayer, C.H.; Curreri, J.R.; Park, Y.J.; Kato, W.Y.; Kawakami, S.

    1989-01-01

    As part of cooperative agreements between the United States and Japan, tests have been performed on the seismic vibration table at the Tadotsu Engineering Laboratory of Nuclear Power Engineering Test Center (NUPEC) in Japan. The objective of the test program was to use the NUPEC vibration table to drive large diameter nuclear power piping to substantial plastic strain with an earthquake excitation and to compare the results with state-of-the-art analysis of the problem. The test model was designed by modifying the 1/2.5 scale model of the PWR primary coolant loop. Elastic and inelastic seismic response behavior of the test model was measured in a number of test runs with an increasing excitation input level up to the limit of the vibration table. In the maximum input condition, large dynamic plastic strains were obtained in the piping. Crack initiation was detected following the second maximum excitation run. The test model was subjected to a maximum acceleration well beyond what nuclear power plants are designed to withstand. This paper describes the overall plan, input motion development, test procedure, test results and comparisons with pre-test analysis. 4 refs., 16 figs., 2 tabs

  10. The High Level Vibration Test program

    International Nuclear Information System (INIS)

    Hofmayer, C.H.; Curreri, J.R.; Park, Y.J.; Kato, W.Y.; Kawakami, S.

    1990-01-01

    As part of cooperative agreements between the United States and Japan, tests have been performed on the seismic vibration table at the Tadotsu Engineering Laboratory of Nuclear Power Engineering Test Center (NUPEC) in Japan. The objective of the test program was to use the NUPEC vibration table to drive large diameter nuclear power piping to substantial plastic strain with an earthquake excitation and to compare the results with state-of-the-art analysis of the problem. The test model was designed by modifying the 1/2.5 scale model of the pressurized water reactor primary coolant loop. Elastic and inelastic seismic response behavior of the test model was measured in a number of test runs with an increasing excitation input level up to the limit of the vibration table. In the maximum input condition, large dynamic plastic strains were obtained in the piping. Crack initiation was detected following the second maximum excitation run. The test model was subjected to a maximum acceleration well beyond what nuclear power plants are designed to withstand. This paper describes the overall plan, input motion development, test procedure, test results and comparisons with pre-test analysis

  11. 7 CFR 58.523 - Laboratory and quality control tests.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Laboratory and quality control tests. 58.523 Section... Service 1 Operations and Operating Procedures § 58.523 Laboratory and quality control tests. (a) Quality control tests shall be made on samples as often as necessary to determine the shelf-life and stability of...

  12. Laboratory testing improves diagnosis and treatment outcomes in primary health care facilities

    Directory of Open Access Journals (Sweden)

    Jane Y. Carter

    2012-10-01

    Setting: Six rural health centres in Kenya. Design: Cross-sectional study to observe change in diagnosis and treatment made by clinical officers after laboratory testing in outpatients attending six rural health centres in Kenya. Subject: The diagnosis and treatment of 1134 patients attending outpatient services in six rural health centres were compared before and after basic laboratory testing. Essential clinical diagnostic equipment and laboratory tests were established at each health centre. Clinical officers and laboratory technicians received on-site refresher training in good diagnostic practices and laboratory procedures before the study began. Results: Laboratory tests were ordered on 704 (62.1% patients. Diagnosis and treatment were changed in 45% of tested patients who returned with laboratory results (21% of all patients attending the clinics. 166 (23.5% patients did not return to the clinician for a final diagnosis and management decision after laboratory testing. Blood slide examination for malaria parasites, wet preparations, urine microscopy and stool microscopy resulted in most changes to diagnosis. There was no significant change in drug costs after laboratory testing. The greatest changes in numbers of recorded diseases following laboratory testing was for intestinal worms (53% and malaria (21%. Conclusion: Effective use of basic laboratory tests at primary health care level significantly improves diagnosis and patient treatment. Use of laboratory testing can be readily incorporated into routine clinical practice. On-site refresher training is an effective means of improving the quality of patient care and communication between clinical and laboratory staff.

  13. 222-S LABORATORY FUME HOOD TESTING STUDY

    International Nuclear Information System (INIS)

    RUELAS, B.H.

    2007-01-01

    The 222-S Laboratory contains 155 active fume hoods that are used to support analytical work with radioactive and/or toxic materials. The performance of a fume hood was brought into question after employees detected odors in the work area while mixing chemicals within the subject fume hood. Following the event, testing of the fume hood was conducted to assess the performance of the fume hood. Based on observations from the testing, it was deemed appropriate to conduct performance evaluations of other fume hoods within the laboratory

  14. Closing the brain-to-brain loop in laboratory testing.

    Science.gov (United States)

    Plebani, Mario; Lippi, Giuseppe

    2011-07-01

    Abstract The delivery of laboratory services has been described 40 years ago and defined with the foremost concept of "brain-to-brain turnaround time loop". This concept consists of several processes, including the final step which is the action undertaken on the patient based on laboratory information. Unfortunately, the need for systematic feedback to improve the value of laboratory services has been poorly understood and, even more risky, poorly applied in daily laboratory practice. Currently, major problems arise from the unavailability of consensually accepted quality specifications for the extra-analytical phase of laboratory testing. This, in turn, does not allow clinical laboratories to calculate a budget for the "patient-related total error". The definition and use of the term "total error" refers only to the analytical phase, and should be better defined as "total analytical error" to avoid any confusion and misinterpretation. According to the hierarchical approach to classify strategies to set analytical quality specifications, the "assessment of the effect of analytical performance on specific clinical decision-making" is comprehensively at the top and therefore should be applied as much as possible to address analytical efforts towards effective goals. In addition, an increasing number of laboratories worldwide are adopting risk management strategies such as FMEA, FRACAS, LEAN and Six Sigma since these techniques allow the identification of the most critical steps in the total testing process, and to reduce the patient-related risk of error. As a matter of fact, an increasing number of laboratory professionals recognize the importance of understanding and monitoring any step in the total testing process, including the appropriateness of the test request as well as the appropriate interpretation and utilization of test results.

  15. Applicability of a generic monitoring program for radioactive waste burial grounds at Oak Ridge National Laboratory and Idaho National Engineering Laboratory

    International Nuclear Information System (INIS)

    1978-07-01

    Six burial grounds were evaluated at Oak Ridge to determine which would be most suitable for testing the generic monitoring approach, and two were selected. Burial Ground 4 was chosen because it is known to be leaking radioactivity and a monitoring program is desirable to determine the source, pattern and extent of the leakage. Burial Ground 6 was chosen because the most complete radiologic and geologic data is available and modern burial practices have been utilized at this site. At the Idaho National Engineering Laboratory (INEL) only one burial ground exists, the Radioactive Waste Management Complex (RWMC). The data available on the burial grounds are insufficient for an adequate understanding of radionuclide migration patterns and accordingly, inadequate for the design of reliable monitoring programs. It was decided, therefore, that preliminary monitoring programs should be designed in order to obtain additional data for a later implementation of reliable monitoring programs. The monitoring programs designed for ORNL consist primarily of the installation of surface water monitoring stations, the surveillance of trench sump wells, a test boring program to study subsurface geologic conditions, a ground water sampling program and the installation of instrumentation, specifically infiltrometers and evaporation pans, to develop data on site water balances. The program designed for the INEL burial ground includes installation of trench sumps, a ground water monitoring program, test borings to further define subsurface geohydrologic conditions and the installation of instrumentation to develop data on the site water balance. The estimated costs of implementing the recommended programs are about $420,820 for monitoring Burial Grounds 4 and 6 at Oak Ridge and $382,060 for monitoring the RWMC at INEL. 12 figures

  16. Laboratory Directed Research and Development Program FY 2006

    Energy Technology Data Exchange (ETDEWEB)

    Hansen (Ed.), Todd

    2007-03-08

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness.

  17. Oak Ridge National Laboratory's isotope enrichment program

    International Nuclear Information System (INIS)

    Tracy, J.G.; Aaron, W.C.

    1997-01-01

    The Isotope Enrichment Program (IEP) at Oak Ridge National Laboratory (ORNL) is responsible for the production and distribution of ∼225 enriched stable isotopes from 50 multi-isotopic elements. In addition, ORNL distributes enriched actinide isotopes and provides extensive physical- and chemical-form processing of enriched isotopes to meet customer requirements. For more than 50 yr, ORNL has been a major provider of enriched isotopes and isotope-related services to research, medical, and industrial institutions throughout the world. Consolidation of the Isotope Distribution Office (IDO), the Isotope Research Materials Laboratory (IRML), and the stable isotope inventories in the Isotope Enrichment Facility (IEF) have improved operational efficiencies and customer services. Recent changes in the IEP have included adopting policies for long-term contracts, which offer program stability and pricing advantages for the customer, and prorated service charges, which greatly improve pricing to the small research users. The former U.S. Department of Energy (DOE) Loan Program has been converted to a lease program, which makes large-quantity or very expensive isotopes available for nondestructive research at a nominal cost. Current efforts are being pursued to improve and expand the isotope separation capabilities as well as the extensive chemical- and physical-form processing that now exists. The IEF's quality management system is ISO 9002 registered and accredited in the United States, Canada, and Europe

  18. Laboratory piping system vibration tests to determine parametric effects on damping in the seismic frequency range

    International Nuclear Information System (INIS)

    Ware, A.G.

    1987-01-01

    A pipe damping research program is being conducted for the United States Nuclear Regulatory Commission at the Idaho National Engineering Laboratory to establish more realistic, best-estimate damping values for use in dynamic structural analyses of piping systems. As part of this program, tests were conducted on a 5-in. (128 mm ID) laboratory piping system to determine the effects of pressure, support configuration, insulation and response amplitude on damping. The tests were designed to produce a wide range of damping values, from very low damping in lightly excited uninsulated systems with few supports, to higher damping under conditions of either/or insulation, high level excitation, and various support arrangements. The effect of pressure at representative seismic levels was considered to be minimal. The supports influence damping at all excitation levels; damping was highest when a mechanical snubber was present in the system. The addition of insulation produced a large increase in damping for the hydraulic shaker excitation tests, but there was no comparable increase for the snapback excitation tests. Once a response amplitude of approximately one-half yield stress was reached, overall damping increased to relatively high levels (>10% of critical)

  19. Overview and status of the SIMMER testing program

    International Nuclear Information System (INIS)

    Scott, J.H.

    1979-01-01

    Los Alamos Scientific Laboratory has undertaken an extensive experiment analysis program to test the results of SIMMER Liquid Metal Fast Breeder Reactor (LMFBR) accident calculations. Initially, we will test the postdisassembly work-energy partition problem. The SIMMER-calculated order-of-magnitude reduction of available kinetic energy following a severe hypothetical core-disruptive accident (HCDA) can be attributed to (1) purely fluid-dynamic effects; and (2) rate-controlled effects, such as phase transitions and heat transfer. We have chosen to test separately each class of mitigator. In this paper we review the experiments initially chosen for testing of each class of mitigator and report on the status of the analyses. We enumerate several problems in SIMMER that experiment analysis has disclosed. Finally, needs for future experiments are discussed

  20. Guidelines for Biosafety Training Programs for Workers Assigned to BSL-3 Research Laboratories.

    Science.gov (United States)

    Homer, Lesley C; Alderman, T Scott; Blair, Heather Ann; Brocard, Anne-Sophie; Broussard, Elaine E; Ellis, Robert P; Frerotte, Jay; Low, Eleanor W; McCarthy, Travis R; McCormick, Jessica M; Newton, JeT'Aime M; Rogers, Francine C; Schlimgen, Ryan; Stabenow, Jennifer M; Stedman, Diann; Warfield, Cheryl; Ntiforo, Corrie A; Whetstone, Carol T; Zimmerman, Domenica; Barkley, Emmett

    2013-03-01

    The Guidelines for Biosafety Training Programs for Workers Assigned to BSL-3 Research Laboratories were developed by biosafety professionals who oversee training programs for the 2 national biocontainment laboratories (NBLs) and the 13 regional biocontainment laboratories (RBLs) that participate in the National Institute of Allergy and Infectious Diseases (NIAID) NBL/RBL Network. These guidelines provide a general training framework for biosafety level 3 (BSL-3) high-containment laboratories, identify key training concepts, and outline training methodologies designed to standardize base knowledge, understanding, and technical competence of laboratory personnel working in high-containment laboratories. Emphasis is placed on building a culture of risk assessment-based safety through competency training designed to enhance understanding and recognition of potential biological hazards as well as methods for controlling these hazards. These guidelines may be of value to other institutions and academic research laboratories that are developing biosafety training programs for BSL-3 research.

  1. Clinical Laboratory Tests in Some Acute Exogenous Poisonings.

    Science.gov (United States)

    Tufkova, Stoilka G; Yankov, Ivan V; Paskaleva, Diana A

    2017-09-01

    There is no specific toxicological screening of clinical laboratory parameters in clinical toxicology when it comes to acute exogenous poisoning. To determine routine clinical laboratory parameters and indicators for assessment of vital functions in patients with acute intoxications. One hundred and fifty-three patients were included in the present study. They were hospitalized in the Department of Clinical Toxicology at St. George University Hospital, Plovdiv for cerebral toxicity inducing medication (n = 45), alcohol (n = 40), heroin abuse (n = 33). The controls were 35. The laboratory tests were conducted in compliance with the standards of the clinical laboratory. We used the following statistical analyses: analysis of variance (the ucriterion of normal distribution, the Student's t-test, dispersion analysis based on ANOVA) and non-parametric analysis. Based on the routine hematological parameters with statistically significant changes in three groups of poisoning are: red blood cells, hematocrit, hemoglobin (except alcohol intoxication) and leukocytes. We found statistically significant changes in serum total protein, sodium and bilirubin. The highest statistical significance is the increased activity of AST and ALT. We present a model for selection of clinical laboratory tests for severe acute poisoning with modern equipment under standardized conditions. The results of the study suggest that the clinical laboratory constellation we used can be used as a mandatory element in the diagnosis of moderate and severe intoxication with the mentioned toxic substances.

  2. Incinerator development program for processing transuranic waste at the Idaho National Engineering Laboratory

    International Nuclear Information System (INIS)

    Hedahl, T.G.

    1982-01-01

    In the fall of 1981, two short-term tests were conducted on a controlled air and a rotary kiln incinerator to assess their potential for processing transuranic (TRU) contaminated waste at the Idaho National Engineering Laboratory (INEL). The primary purpose of the test program was a proof-of-principle verification that the incinerators could achieve near-complete combustion of the combustible portion of the waste, while mixed with high percentages of noncombustible and metal waste materials. Other important test objectives were to obtain system design information including off-gas and end-product characteristics and incinerator operating parameters. Approximately 7200 kg of simulated (non-TRU) waste from the INEL were processed during the two tests

  3. [Quality Management and Quality Specifications of Laboratory Tests in Clinical Studies--Challenges in Pre-Analytical Processes in Clinical Laboratories].

    Science.gov (United States)

    Ishibashi, Midori

    2015-01-01

    The cost, speed, and quality are the three important factors recently indicated by the Ministry of Health, Labour and Welfare (MHLW) for the purpose of accelerating clinical studies. Based on this background, the importance of laboratory tests is increasing, especially in the evaluation of clinical study participants' entry and safety, and drug efficacy. To assure the quality of laboratory tests, providing high-quality laboratory tests is mandatory. For providing adequate quality assurance in laboratory tests, quality control in the three fields of pre-analytical, analytical, and post-analytical processes is extremely important. There are, however, no detailed written requirements concerning specimen collection, handling, preparation, storage, and shipping. Most laboratory tests for clinical studies are performed onsite in a local laboratory; however, a part of laboratory tests is done in offsite central laboratories after specimen shipping. As factors affecting laboratory tests, individual and inter-individual variations are well-known. Besides these factors, standardizing the factors of specimen collection, handling, preparation, storage, and shipping, may improve and maintain the high quality of clinical studies in general. Furthermore, the analytical method, units, and reference interval are also important factors. It is concluded that, to overcome the problems derived from pre-analytical processes, it is necessary to standardize specimen handling in a broad sense.

  4. The high level vibration test program

    International Nuclear Information System (INIS)

    Hofmayer, C.H.; Curreri, J.R.; Park, Y.J.; Kato, W.Y.; Kawakami, S.

    1989-01-01

    As part of cooperative agreements between the US and Japan, tests have been performed on the seismic vibration table at the Tadotsu Engineering Laboratory of Nuclear Power Engineering Test Center (NUPEC) in Japan. The objective of the test program was to use the NUPEC vibration table to drive large diameter nuclear power piping to substantial plastic strain with an earthquake excitation and to compare the results with state-of-the-art analysis of the problem. The test model was subjected to a maximum acceleration well beyond what nuclear power plants are designed to withstand. A modified earthquake excitation was applied and the excitation level was increased carefully to minimize the cumulative fatigue damage due to the intermediate level excitations. Since the piping was pressurized, and the high level earthquake excitation was repeated several times, it was possible to investigate the effects of ratchetting and fatigue as well. Elastic and inelastic seismic response behavior of the test model was measured in a number of test runs with an increasing excitation input level up to the limit of the vibration table. In the maximum input condition, large dynamic plastic strains were obtained in the piping. Crack initiation was detected following the second maximum excitation run. Crack growth was carefully monitored during the next two additional maximum excitation runs. The final test resulted in a maximum crack depth of approximately 94% of the wall thickness. The HLVT (high level vibration test) program has enhanced understanding of the behavior of piping systems under severe earthquake loading. As in other tests to failure of piping components, it has demonstrated significant seismic margin in nuclear power plant piping

  5. LDRD 2016 Annual Report: Laboratory Directed Research and Development Program Activities

    Energy Technology Data Exchange (ETDEWEB)

    Hatton, D. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2017-03-31

    Each year, Brookhaven National Laboratory (BNL) is required to provide a program description and overview of its Laboratory Directed Research and Development Program (LDRD) to the Department of Energy (DOE) in accordance with DOE Order 413.2C dated October 22, 2015. This report provides a detailed look at the scientific and technical activities for each of the LDRD projects funded by BNL in FY 2016, as required. In FY 2016, the BNL LDRD Program funded 48 projects, 21 of which were new starts, at a total cost of $11.5M. The investments that BNL makes in its LDRD program support the Laboratory’s strategic goals. BNL has identified four Critical Outcomes that define the Laboratory’s scientific future and that will enable it to realize its overall vision. Two operational Critical Outcomes address essential operational support for that future: renewal of the BNL campus; and safe, efficient laboratory operations.

  6. Sandia Laboratories environment and safety programs

    International Nuclear Information System (INIS)

    Zak, B.D.; McGrath, P.E.; Trauth, C.A. Jr.

    1975-01-01

    Sandia, one of ERDA's largest laboratories, is primarily known for its extensive work in the nuclear weapons field. In recent years, however, Sandia's role has expanded to embrace sizeable programs in the energy, resource recovery, and the environment and safety fields. In this latter area, Sandia has programs which address nuclear, fossil fuel, and general environment and safety issues. Here we survey ongoing activities and describe in more detail aa few projects of particular interest. These range from a study of the impact of sealed disposal of radioactive wastes, through reactor safety and fossil fuel plume chemistry, to investigations of the composition and dynamics of the stratosphere

  7. A quality assurance program for nuclear power reactor materials tests at the Ford nuclear reactor

    International Nuclear Information System (INIS)

    Burn, R.R.

    1989-01-01

    The University of Michigan Nuclear Reactor Laboratory Quality Assurance Program has been established to assure that materials testing services provided to electric utilities produce accurate results in accordance with industry standards, sound engineering practice, and customer requirements. The program was prepared to comply with applicable requirements of 10CFR50, Appendix B, of the Code of Federal Regulations and a standard of the American National Standards Institute (ANSI), N45.2. The paper discusses the quality assurance program applicability, organization, qualification and training of personnel, material identification and control, examination and testing, measuring and test equipment, nonconforming test equipment, records, audits, and distribution

  8. Accuracy in HIV Rapid Testing among Laboratory and Non-laboratory Personnel in Zambia: Observations from the National HIV Proficiency Testing System.

    Directory of Open Access Journals (Sweden)

    Sheila Mwangala

    Full Text Available Despite rapid task-shifting and scale-up of HIV testing services in high HIV prevalence countries, studies evaluating accuracy remain limited. This study aimed to assess overall accuracy level and factors associated with accuracy in HIV rapid testing in Zambia.Accuracy was investigated among rural and urban HIV testing sites participating in two annual national HIV proficiency testing (PT exercises conducted in 2009 (n = 282 sites and 2010 (n = 488 sites. Testers included lay counselors, nurses, laboratory personnel and others. PT panels of five dry tube specimens (DTS were issued to testing sites by the national reference laboratory (NRL. Site accuracy level was assessed by comparison of reported results to the expected results. Non-parametric rank tests and multiple linear regression models were used to assess variation in accuracy between PT cycles and between tester groups, and to examine factors associated with accuracy respectively.Overall accuracy level was 93.1% (95% CI: 91.2-94.9 in 2009 and 96.9% (95% CI: 96.1-97.8 in 2010. Differences in accuracy were seen between the tester groups in 2009 with laboratory personnel being more accurate than non-laboratory personnel, while in 2010 no differences were seen. In both PT exercises, lay counselors and nurses had more difficulties interpreting results, with more occurrences of false-negative, false-positive and indeterminate results. Having received the standard HIV rapid testing training and adherence to the national HIV testing algorithm were positively associated with accuracy.The study showed an improvement in tester group and overall accuracy from the first PT exercise to the next. Average number of incorrect test results per 1000 tests performed was reduced from 69 to 31. Further improvement is needed, however, and the national HIV proficiency testing system seems to be an important tool in this regard, which should be continued and needs to be urgently strengthened.

  9. Spent fuel sabotage aerosol test program :FY 2005-06 testing and aerosol data summary

    International Nuclear Information System (INIS)

    Gregson, Michael Warren; Brockmann, John E.; Nolte, O.; Loiseau, O.; Koch, W.; Molecke, Martin Alan; Autrusson, Bruno; Pretzsch, Gunter Guido; Billone, M. C.; Lucero, Daniel A.; Burtseva, T.; Brucher, W; Steyskal, Michele D.

    2006-01-01

    . This spent fuel sabotage--aerosol test program, performed primarily at Sandia National Laboratories, with support provided by both the U.S. Department of Energy and the Nuclear Regulatory Commission, had significant inputs from, and is strongly supported and coordinated by both the U.S. and international program participants in Germany, France, and the U.K., as part of the international Working Group for Sabotage Concerns of Transport and Storage Casks, WGSTSC

  10. Laboratory procedures for waste form testing

    International Nuclear Information System (INIS)

    Mast, E.S.

    1994-01-01

    The 100 and 300 areas of the Hanford Site are included on the US Environmental Protection Agencies (EPA) National Priorities List under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA). Soil washing is a treatment process that is being considered for the remediation of the soil in these areas. Contaminated soil washing fines can be mixed or blended with cementations materials to produce stable waste forms that can be used for beneficial purposes in mixed or low-level waste landfills, burial trenches, environmental restoration sites, and other applications. This process has been termed co-disposal. The Co-Disposal Treatability Study Test Plan is designed to identify a range of cement-based formulations that could be used in disposal efforts in Hanford in co-disposal applications. The purpose of this document is to provide explicit procedural information for the testing of co-disposal formulations. This plan also provides a discussion of laboratory safety and quality assurance necessary to ensure safe, reproducible testing in the laboratory

  11. Laboratory procedures for waste form testing

    Energy Technology Data Exchange (ETDEWEB)

    Mast, E.S.

    1994-09-19

    The 100 and 300 areas of the Hanford Site are included on the US Environmental Protection Agencies (EPA) National Priorities List under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA). Soil washing is a treatment process that is being considered for the remediation of the soil in these areas. Contaminated soil washing fines can be mixed or blended with cementations materials to produce stable waste forms that can be used for beneficial purposes in mixed or low-level waste landfills, burial trenches, environmental restoration sites, and other applications. This process has been termed co-disposal. The Co-Disposal Treatability Study Test Plan is designed to identify a range of cement-based formulations that could be used in disposal efforts in Hanford in co-disposal applications. The purpose of this document is to provide explicit procedural information for the testing of co-disposal formulations. This plan also provides a discussion of laboratory safety and quality assurance necessary to ensure safe, reproducible testing in the laboratory.

  12. Tests for oil/dispersant toxicity: In situ laboratory assays

    International Nuclear Information System (INIS)

    Wright, D.A.; Coelho, G.M.; Aurand, D.V.

    1995-01-01

    As part of its readiness program in oil spill response, the Marine Pollution Control Unit (MPCU), Department of Transport, U.K. conducts annual field trials in the North Sea, approximately 30 nautical miles from the southeast coast of England. The trials take the form of controlled releases of crude oil or Medium Fuel/Gas Oil mix (MFO), with and without the application of Corexit 9527 dispersant. In 1994 and 1995 the authors conducted a series of in situ toxicity bioassays in association with these spills with included 48h LC50 tests for turbot (Scophthalmus maximus) and oyster (Crassostrea gigas) larvae, a 48 h oyster (C. gigas) embryonic development test and two full life-cycle assays using the copepods Acartia tonsa and Tisbe battagliai. Tests were also conducted in the Chesapeake Bay laboratory using estuarine species including the copepod Eurytemora affinis and the inland silverside Menidia beryllina. Here, the authors report on the results of these assays, together with 1996 in situ toxicity data resulting from Norwegian field trials in the northern North Sea

  13. Laboratory Directed Research and Development Program FY2004

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Todd C.

    2005-03-22

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Berkeley Lab's research and the Laboratory Directed Research and Development (LDRD) program support DOE's Strategic Goals that are codified in DOE's September 2003 Strategic Plan, with a primary focus on Advancing Scientific Understanding. For that goal, the Fiscal Year (FY) 2004 LDRD projects support every one of the eight strategies described in the plan. In addition, LDRD efforts support the goals of Investing in America's Energy Future (six of the fourteen strategies), Resolving the Environmental Legacy (four of the eight strategies), and Meeting National Security Challenges (unclassified fundamental research that supports stockpile safety and nonproliferation programs). The LDRD supports Office of Science strategic plans, including the 20 year Scientific Facilities Plan and the draft Office of Science Strategic Plan. The research also

  14. Use of laboratory test results in patient management by clinicians in Malawi.

    Science.gov (United States)

    Moyo, Kundai; Porter, Carol; Chilima, Ben; Mwenda, Reuben; Kabue, Mark; Zungu, Lutho; Sarr, Abdoulaye

    2015-11-18

    Malawi has a high burden of infectious disease. The expansion of programmes targeting these diseases requires a strong laboratory infrastructure to support both diagnosis and treatment. To assess the use of laboratory test results in patient management and to determine the requirements for improving laboratory services. A cross-sectional study was conducted in 2012 to survey practising clinicians. Two hospitals were purposively selected for observations of clinicians ordering laboratory tests. Twelve management-level key informants were interviewed. Descriptive statistics were conducted. A total of 242 clinicians were identified and 216 (89%) were interviewed. Of these, 189 (87%) reported doubting laboratory test results at some point. Clinicians most often doubted the quality of haematology (67%), followed by malaria (53%) and CD4 (22%) test results. A total of 151 (70%) clinicians reported using laboratory tests results in patient management. Use of laboratory test results at all times in patient management varied by the type of health facility ( P management. Key informants reported that the quality of laboratory services was good and useful, but that services were often unavailable. Gaps in the public laboratory system were evident. Key recommendations to enhance the use of laboratory test results in patient management were to strengthen the supply chain, reduce turn-around times, improve the test menu and improve the laboratory infrastructure.

  15. 7 CFR 58.442 - Laboratory and quality control tests.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Laboratory and quality control tests. 58.442 Section... Service 1 Operations and Operating Procedures § 58.442 Laboratory and quality control tests. (a) Chemical... Methods or by other methods giving equivalent results. (b) Weight or volume control. Representative...

  16. Inadequate Information in Laboratory Test Requisition in a Tertiary ...

    African Journals Online (AJOL)

    Objectives: This study examined the pattern of deficiencies in the laboratory test requisition by doctors at the University of Benin Teaching Hospital, Benin City, Nigeria, with a view to suggesting strategies of reducing error rates in laboratory test requisition. Materials and Method: The study generated data through ...

  17. LDRD 2012 Annual Report: Laboratory Directed Research and Development Program Activities

    Energy Technology Data Exchange (ETDEWEB)

    Bookless, William [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2012-12-31

    Each year, Brookhaven National Laboratory (BNL) is required to provide a program description and overview of its Laboratory Directed Research and Development Program (LDRD) to the Department of Energy in accordance with DOE Order 413.2B dated April 19, 2006. This report provides a detailed look at the scientific and technical activities for each of the LDRD projects funded by BNL in FY2012, as required. In FY2012, the BNL LDRD Program funded 52 projects, 14 of which were new starts, at a total cost of $10,061,292.

  18. LDRD 2014 Annual Report: Laboratory Directed Research and Development Program Activities

    Energy Technology Data Exchange (ETDEWEB)

    Hatton, Diane [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2015-03-01

    Each year, Brookhaven National Laboratory (BNL) is required to provide a program description and overview of its Laboratory Directed Research and Development Program (LDRD) to the Department of Energy (DOE) in accordance with DOE Order 413.2B dated April 19, 2006. This report provides a detailed look at the scientific and technical activities for each of the LDRD projects funded by BNL in FY 2014, as required. In FY 2014, the BNL LDRD Program funded 40 projects, 8 of which were new starts, at a total cost of $9.6M.

  19. LDRD 2015 Annual Report: Laboratory Directed Research and Development Program Activities

    Energy Technology Data Exchange (ETDEWEB)

    Hatton, D. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2015-12-31

    Each year, Brookhaven National Laboratory (BNL) is required to provide a program description and overview of its Laboratory Directed Research and Development Program (LDRD) to the Department of Energy (DOE) in accordance with DOE Order 413.2B dated April 19, 2006. This report provides a detailed look at the scientific and technical activities for each of the LDRD projects funded by BNL in FY 2015, as required. In FY 2015, the BNL LDRD Program funded 43 projects, 12 of which were new starts, at a total cost of $9.5M.

  20. Associated Western Universities summer participant program at the Lawrence Livermore National Laboratory, Summer 1997

    Energy Technology Data Exchange (ETDEWEB)

    Williams, B.

    1997-08-01

    The Associated Western Universities, Inc. (AWU) supports a student summer program at Lawrence Livermore National Laboratory (LLNL). This program is structured so that honors undergraduate students may participate in the Laboratory`s research program under direct supervision of senior Laboratory scientists. Included in this report is a list of the AWU participants for the summer of 1997. All students are required to submit original reports of their summer activities in a format of their own choosing. These unaltered student reports constitute the major portion of this report.

  1. Updating the immunology curriculum in clinical laboratory science.

    Science.gov (United States)

    Stevens, C D

    2000-01-01

    To determine essential content areas of immunology/serology courses at the clinical laboratory technician (CLT) and clinical laboratory scientist (CLS) levels. A questionnaire was designed which listed all major topics in immunology and serology. Participants were asked to place a check beside each topic covered. For an additional list of serological and immunological laboratory testing, participants were asked to indicate if each test was performed in either the didactic or clinical setting, or not performed at all. A national survey of 593 NAACLS approved CLT and CLS programs was conducted by mail under the auspices of ASCLS. Responses were obtained from 158 programs. Respondents from all across the United States included 60 CLT programs, 48 hospital-based CLS programs, 45 university-based CLS programs, and 5 university-based combined CLT and CLS programs. The survey was designed to enumerate major topics included in immunology and serology courses by a majority of participants at two distinct educational levels, CLT and CLS. Laboratory testing routinely performed in student laboratories as well as in the clinical setting was also determined for these two levels of practitioners. Certain key topics were common to most immunology and serology courses. There were some notable differences in the depth of courses at the CLT and CLS levels. Laboratory testing associated with these courses also differed at the two levels. Testing requiring more detailed interpretation, such as antinuclear antibody patterns (ANAs), was mainly performed by CLS students only. There are certain key topics as well as specific laboratory tests that should be included in immunology/serology courses at each of the two different educational levels to best prepare students for the workplace. Educators can use this information as a guide to plan a curriculum for such courses.

  2. SSCL magnet systems quality program implementation for laboratory and industry

    International Nuclear Information System (INIS)

    Warner, D.G.; Bever, D.L.

    1992-01-01

    The development and delivery of reliable and producible magnets for the Superconducting Super Collider Laboratory (SSCL) require the teamwork of a large and diverse workforce composed of personnel with backgrounds in laboratory research, defense, and energy. The SSCL Magnet Quality Program is being implemented with focus on three definitive objectives: (1) communication of requirements, (2) teamwork, and (3) verification. Examination of the SSCL Magnet Systems Division's (MSD) current and planned approach to implementation of the SSCL Magnet Quality Program utilizing these objectives is discussed

  3. Equipment qualification testing methodology research at Sandia Laboratories

    International Nuclear Information System (INIS)

    Jeppesen, D.

    1983-01-01

    The Equipment Qualification Research Testing (EQRT) program is an evolutionary outgrowth of the Qualification Testing Evaluation (QTE) program at Sandia. The primary emphasis of the program has been qualification methodology research. The EQRT program offers to the industry a research-oriented perspective on qualification-related component performance, as well as refinements to component testing standards which are based upon actual component testing research

  4. Sandia National Laboratories, California Hazardous Materials Management Program annual report.

    Energy Technology Data Exchange (ETDEWEB)

    Brynildson, Mark E.

    2011-02-01

    The annual program report provides detailed information about all aspects of the Sandia National Laboratories, California (SNL/CA) Hazardous Materials Management Program. It functions as supporting documentation to the SNL/CA Environmental Management System Program Manual. This program annual report describes the activities undertaken during the calender past year, and activities planned in future years to implement the Hazardous Materials Management Program, one of six programs that supports environmental management at SNL/CA.

  5. The Laboratory Diagnosis of HIV Infections

    Directory of Open Access Journals (Sweden)

    Margaret Fearon

    2005-01-01

    Full Text Available HIV diagnostic testing has come a long way since its inception in the early 1980s. Current enzyme immunoassays are sensitive enough to detect antibody as early as one to two weeks after infection. A variety of other assays are essential to confirm positive antibody screens (Western blot, polymerase chain reaction [PCR], provide an adjunct to antibody testing (p24 antigen, PCR, or provide additional information for the clinician treating HIV-positive patients (qualitative and quantitative PCR, and genotyping. Most diagnostic laboratories have complex testing algorithms to ensure accuracy of results and optimal use of laboratory resources. The choice of assays is guided by the initial screening results and the clinical information provided by the physician; both are integral to the laboratory's ability to provide an accurate laboratory diagnosis. Laboratories should also provide specific information on specimen collection, storage and transport so that specimen integrity is not compromised, thereby preserving the accuracy of laboratory results. Point of Care tests have become increasingly popular in the United States and some places in Canada over the past several years. These tests provide rapid, on-site HIV results in a format that is relatively easy for clinic staff to perform. However, the performance of these tests requires adherence to good laboratory quality control practices, as well as the backup of a licensed diagnostic laboratory to provide confirmation and resolution of positive or indeterminate results. Laboratory quality assurance programs and the participation in HIV proficiency testing programs are essential to ensure that diagnostic laboratories provide accurate, timely and clinically relevant laboratory results.

  6. Proficiency testing program for the determination of total arsenic, cadmium, and lead in seawater shrimp.

    Science.gov (United States)

    Kong, Mei-Fung; Chan, Serena; Wong, Yiu-Chung

    2008-01-01

    The proficiency testing (PT) program for 97 worldwide laboratories for determining total arsenic, cadmium, and lead in seawater shrimp under the auspices of the Asia-Pacific Laboratory Accreditation Cooperation (APLAC) is discussed. The program is one of the APLAC PT series whose primary purposes are to establish mutual agreement on the equivalence of the operation of APLAC member laboratories and to take corrective actions if testing deficiencies are identified. Pooled data for Cd and Pb were normally distributed with interlaboratory variations of 21.9 and 34.8%, respectively. The corresponding consensus mean values estimated by robust statistics were in good agreement with those obtained in the homogeneity tests. However, a bimodal distribution was observed from the determination of total As, in which 14 out of 74 participants reported much smaller values (0.482-6.4 mg/kg) as compared with the mean values of 60.9 mg/kg in the homogeneity test. The use of consensus mean is known to have significant deviation from the true value in bi- or multimodal distribution. Therefore, the mode value, a better estimate of central tendency, was chosen to assess participants' performance for total As. Estimates of the overall uncertainty from participants varied in this program, and some were recommended to acquire more comprehensive exposure toward important criteria as stipulated in ISO/IEC 17025.

  7. A prequalifying program for evaluating the analytical performance of commercial laboratories

    International Nuclear Information System (INIS)

    Reith, C.C.; Bishop, C.T.

    1987-01-01

    Soil and water samples were spiked with known activities of radionuclides and sent to seven commercial laboratories that had expressed an interest in analyzing environmental samples for the Waste Isolation Pilot Plant (WIPP). This Prequalifying Program was part of the selection process for an analytical subcontractor for a three-year program of baseline radiological surveillance around the WIPP site. Both media were spiked at three different activity levels with several transuranic radionuclides, as well as tritium, fission products, and activation products. Laboratory performance was evaluated by calculating relative error for each radionuclide in each sample, assigning grade values, and compiling grades into report cards for each candidate. Results for the five laboratories completing the Prequalifying Program were pooled to reveal differing degrees of difficulty among the treatments and radionuclides. Interlaboratory comparisons revealed systematic errors in the performance of one candidate. The final report cards contained clear differences among overall grades for the five laboratories, enabling analytical performance to be used as a quantitative criterion in the selection of an analytical subcontractor. (author)

  8. To test or not to test? Laboratory support for the diagnosis of Lyme borreliosis

    DEFF Research Database (Denmark)

    Dessau, Ram B; van Dam, Alje P; Fingerle, Volker

    2018-01-01

    rational use of laboratory testing in patients with clinically suspected Lyme borreliosis. SOURCES: This is a narrative review combining various aspects of the clinical and laboratory diagnosis with an educational purpose. The literature search was based on existing systematic reviews, national...... and international guidelines and supplemented with specific citations. IMPLICATIONS: The main recommendations according to current European case definitions for Lyme borreliosis are as follows: Typical erythema migrans should be diagnosed clinically and does not require laboratory testing, the diagnosis of Lyme...

  9. Combining program visualization with programming workspace to assist students for completing programming laboratory task

    Directory of Open Access Journals (Sweden)

    Elvina Elvina

    2018-06-01

    Full Text Available Numerous Program Visualization tools (PVs have been developed for assisting novice students to understand their source code further. However, none of them are practical to be used in the context of completing programming laboratory task; students are required to keep switching between PV and programming workspace when they need to know how their code works. This paper combines PV with programming workspace to handle such issue. Resulted tool (which is named PITON has 13 features extracted from PythonTutor, PyCharm, and student’s feedbacks about PythonTutor. According to think-aloud and user study, PITON is more practical to be used than a combination of PythonTutor and PyCharm. Further, its features are considerably helpful; students rated these features as useful and frequently used.

  10. Are laboratory tests always needed? Frequency and causes of laboratory overuse in a hospital setting.

    Science.gov (United States)

    Cadamuro, Janne; Gaksch, Martin; Wiedemann, Helmut; Lippi, Giuseppe; von Meyer, Alexander; Pertersmann, Astrid; Auer, Simon; Mrazek, Cornelia; Kipman, Ulrike; Felder, Thomas K; Oberkofler, Hannes; Haschke-Becher, Elisabeth

    2018-04-01

    Inappropriate utilization of laboratory resources is an increasing concern especially in high-throughput facilities. Until now, no reliable information has been published addressing to which extent laboratory results are actually used for clinical decision-making. Therefore, we aimed to close this gap using a novel retrospective approach including a survey of clinicians and nurses. We retrospectively evaluated the number of re-orders for potassium (K), lactate dehydrogenase (LD), aspartate-aminotransferase (AST), activated partial thromboplastin-time (APTT) and prothrombin-time/INR (PT/INR), after the initial order had to be cancelled due to preanalytical non-conformities. We analyzed subgroups regarding time to re-order, ward and sample priority (urgent vs. routine). Subsequently, we surveyed clinicians and nurses, asking for their estimate of the amount of failed re-orders as well as for possible reasons. From initially cancelled tests, only ~20% of K, LD, AST and ~30% of APTT and PT/INR tests were re-ordered within 24 h. 70% of the investigated clinical chemistry and 60% of coagulation tests were re-ordered one week after cancellation or not at all. Survey participants quite accurately estimated these numbers. Routine laboratory panels, short stay of out-patients, obsolete test results and avoiding additional phlebotomies were the main reasons for not re-ordering cancelled tests. Overall, 60-70% of test results in the investigated assays ordered in a high throughput laboratory are potentially inappropriate or of doubtful clinically importance. Although clinicians and nurses are aware of this situation, it is the duty of laboratory specialists to overcome overutilization in close collaboration with all involved healthcare workers. Copyright © 2018 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  11. Assessment of the quality of test results from selected civil engineering material testing laboratories in Tanzania

    CSIR Research Space (South Africa)

    Mbawala, SJ

    2017-12-01

    Full Text Available Civil and geotechnical engineering material testing laboratories are expected to produce accurate and reliable test results. However, the ability of laboratories to produce accurate and reliable test results depends on many factors, among others...

  12. National Research Council Research Associateships Program with Methane Hydrates Fellowships Program/National Energy Technology Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Basques, Eric O. [National Academy of Sciences, Washington, DC (United States)

    2014-03-20

    This report summarizes work carried out over the period from July 5, 2005-January 31, 2014. The work was carried out by the National Research Council Research Associateships Program of the National Academies, under the US Department of Energy's National Energy Technology Laboratory (NETL) program. This Technical Report consists of a description of activity from 2005 through 2014, broken out within yearly timeframes, for NRC/NETL Associateships researchers at NETL laboratories which includes individual tenure reports from Associates over this time period. The report also includes individual tenure reports from associates over this time period. The report also includes descriptions of program promotion efforts, a breakdown of the review competitions, awards offered, and Associate's activities during their tenure.

  13. Towards a rational antimicrobial testing policy in the laboratory.

    Science.gov (United States)

    Banaji, N; Oommen, S

    2011-01-01

    Antimicrobial policy for prophylactic and therapeutic use of antimicrobials in a tertiary care setting has gained importance. A hospital's antimicrobial policy as laid down by its hospital infection control team needs to include inputs from the microbiology laboratory, besides the pharmacy and therapeutic committee. Therefore, it is of utmost importance that clinical microbiologists across India follow international guidelines and also take into account local settings, especially detection and presence of resistance enzymes. This article draws a framework for rational antimicrobial testing in our laboratories in tertiary care centers, from the Clinical and Laboratory Standards Institute guidelines. It does not address testing methodologies but suggests ways and means by which antimicrobial susceptibility reporting can be rendered meaningful not only to the treating physician but also to the resistance monitoring epidemiologist. It hopes to initiate some standardization in rational choice of antimicrobial testing in laboratories in the country pertaining to nonfastidious bacteria.

  14. The integrated in situ testing program for the Waste Isolation Pilot Plant (WIPP)

    International Nuclear Information System (INIS)

    Matalucci, R.V.

    1987-03-01

    The US Department of Energy (DOE) is developing the Waste Isolation Pilot Plant (WIPP) Project in southeastern New Mexico as a research and development (R and D) facility for examining the response of bedded (layered) salt to the emplacement of radioactive wastes generated from defense programs. The WIPP Experimental Program consists of a technology development program, including laboratory testing and theoretical analysis activities, and an in situ testing program that is being done 659 m underground at the project site. This experimental program addresses three major technical areas that concern (1) thermal/structural interactions, (2) plugging and sealing, and (3) waste package performance. To ensure that the technical issues involved in these areas are investigated with appropriate emphasis and timing, an in situ testing plan was developed to integrate the many activities and tasks associated with the technical issues of waste disposal. 5 refs., 4 figs

  15. Quality management and accreditation in a mixed research and clinical hair testing analytical laboratory setting-a review.

    Science.gov (United States)

    Fulga, Netta

    2013-06-01

    Quality management and accreditation in the analytical laboratory setting are developing rapidly and becoming the standard worldwide. Quality management refers to all the activities used by organizations to ensure product or service consistency. Accreditation is a formal recognition by an authoritative regulatory body that a laboratory is competent to perform examinations and report results. The Motherisk Drug Testing Laboratory is licensed to operate at the Hospital for Sick Children in Toronto, Ontario. The laboratory performs toxicology tests of hair and meconium samples for research and clinical purposes. Most of the samples are involved in a chain of custody cases. Establishing a quality management system and achieving accreditation became mandatory by legislation for all Ontario clinical laboratories since 2003. The Ontario Laboratory Accreditation program is based on International Organization for Standardization 15189-Medical laboratories-Particular requirements for quality and competence, an international standard that has been adopted as a national standard in Canada. The implementation of a quality management system involves management commitment, planning and staff education, documentation of the system, validation of processes, and assessment against the requirements. The maintenance of a quality management system requires control and monitoring of the entire laboratory path of workflow. The process of transformation of a research/clinical laboratory into an accredited laboratory, and the benefits of maintaining an effective quality management system, are presented in this article.

  16. Laboratory Directed Research and Development Program. FY 1993

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-01

    This report is compiled from annual reports submitted by principal investigators following the close of fiscal year 1993. This report describes the projects supported and summarizes their accomplishments. The program advances the Laboratory`s core competencies, foundations, scientific capability, and permits exploration of exciting new opportunities. Reports are given from the following divisions: Accelerator and Fusion Research, Chemical Sciences, Earth Sciences, Energy and Environment, Engineering, Environment -- Health and Safety, Information and Computing Sciences, Life Sciences, Materials Sciences, Nuclear Science, Physics, and Structural Biology. (GHH)

  17. Inter-laboratory proficiency tests to detect viral fish diseases

    DEFF Research Database (Denmark)

    Kahns, Søren; Nicolajsen, Nicole; Skall, Helle Frank

    An inter-laboratory proficiency test has ben provided by the European Community Laboratory (CRL) for Fish Diseases every year since 1996. The test is provided to all European National Reference Laboratories (NRLs) that are obliged to participate and to a limited number of non-European NRLs, making......) but also to assess their ability to differentiate other fish viruses as spring viraemia of carp virus, infectious pancreatic necrosis virus, perch rhabdovirus etc. Five coded ampoules are provided to participants containing lyophilised supernatant from infected cell cultures. The CRL collect the data...

  18. Radiation Effects and Component Hardening testing program at the Oak Ridge National Laboratory

    International Nuclear Information System (INIS)

    Draper, J.V.; Weil, B.S.; Chesser, J.B.

    1993-01-01

    This paper describes Phase II of the Radiation Effects and Component Hardening (REACH) testing program, performed as part of the joint collaborative agreement between the United States Department of Energy (USDOE) and the Power Reactor and Nuclear Fuel Development Corporation (PNC) of Japan, Components and materials were submitted to 10 5 R/hr gamma radiation fields for 10,000 hr, producing accumulated doses of 10 9 R; most performed as expected

  19. Laboratory tests of hydraulic fracturing and swell healing

    DEFF Research Database (Denmark)

    Thunbo, Christensen Claes; Foged, Christensen Helle; Foged, Niels

    1998-01-01

    New laboratory test set-ups and test procedures are described - for testing the formation of hydraulically induced fractures as well as the potential for subsequent fracture closurefrom the relase of a swelling potential. The main purpose with the tests is to provide information on fracturing str...

  20. Argonne National Laboratory Annual Report of Laboratory Directed Research and Development program activities FY 2011.

    Energy Technology Data Exchange (ETDEWEB)

    (Office of The Director)

    2012-04-25

    As a national laboratory Argonne concentrates on scientific and technological challenges that can only be addressed through a sustained, interdisciplinary focus at a national scale. Argonne's eight major initiatives, as enumerated in its strategic plan, are Hard X-ray Sciences, Leadership Computing, Materials and Molecular Design and Discovery, Energy Storage, Alternative Energy and Efficiency, Nuclear Energy, Biological and Environmental Systems, and National Security. The purposes of Argonne's Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel technical concepts, enhance the Laboratory's research and development (R and D) capabilities, and pursue its strategic goals. projects are selected from proposals for creative and innovative R and D studies that require advance exploration before they are considered to be sufficiently developed to obtain support through normal programmatic channels. Among the aims of the projects supported by the LDRD Program are the following: establishment of engineering proof of principle, assessment of design feasibility for prospective facilities, development of instrumentation or computational methods or systems, and discoveries in fundamental science and exploratory development.

  1. Argonne National Laboratory Annual Report of Laboratory Directed Research and Development program activities FY 2010.

    Energy Technology Data Exchange (ETDEWEB)

    (Office of The Director)

    2012-04-25

    As a national laboratory Argonne concentrates on scientific and technological challenges that can only be addressed through a sustained, interdisciplinary focus at a national scale. Argonne's eight major initiatives, as enumerated in its strategic plan, are Hard X-ray Sciences, Leadership Computing, Materials and Molecular Design and Discovery, Energy Storage, Alternative Energy and Efficiency, Nuclear Energy, Biological and Environmental Systems, and National Security. The purposes of Argonne's Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel technical concepts, enhance the Laboratory's research and development (R and D) capabilities, and pursue its strategic goals. projects are selected from proposals for creative and innovative R and D studies that require advance exploration before they are considered to be sufficiently developed to obtain support through normal programmatic channels. Among the aims of the projects supported by the LDRD Program are the following: establishment of engineering proof of principle, assessment of design feasibility for prospective facilities, development of instrumentation or computational methods or systems, and discoveries in fundamental science and exploratory development.

  2. Standard guide for establishing a quality assurance program for analytical chemistry laboratories within the nuclear industry

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2006-01-01

    1.1 This guide covers the establishment of a quality assurance (QA) program for analytical chemistry laboratories within the nuclear industry. Reference to key elements of ANSI/ISO/ASQC Q9001, Quality Systems, provides guidance to the functional aspects of analytical laboratory operation. When implemented as recommended, the practices presented in this guide will provide a comprehensive QA program for the laboratory. The practices are grouped by functions, which constitute the basic elements of a laboratory QA program. 1.2 The essential, basic elements of a laboratory QA program appear in the following order: Section Organization 5 Quality Assurance Program 6 Training and Qualification 7 Procedures 8 Laboratory Records 9 Control of Records 10 Control of Procurement 11 Control of Measuring Equipment and Materials 12 Control of Measurements 13 Deficiencies and Corrective Actions 14

  3. Towards a rational antimicrobial testing policy in the laboratory

    Directory of Open Access Journals (Sweden)

    N Banaji

    2011-01-01

    Full Text Available Antimicrobial policy for prophylactic and therapeutic use of antimicrobials in a tertiary care setting has gained importance. A hospital′s antimicrobial policy as laid down by its hospital infection control team needs to include inputs from the microbiology laboratory, besides the pharmacy and therapeutic committee. Therefore, it is of utmost importance that clinical microbiologists across India follow international guidelines and also take into account local settings, especially detection and presence of resistance enzymes. This article draws a framework for rational antimicrobial testing in our laboratories in tertiary care centers, from the Clinical and Laboratory Standards Institute guidelines. It does not address testing methodologies but suggests ways and means by which antimicrobial susceptibility reporting can be rendered meaningful not only to the treating physician but also to the resistance monitoring epidemiologist. It hopes to initiate some standardization in rational choice of antimicrobial testing in laboratories in the country pertaining to nonfastidious bacteria.

  4. Stochastic optimization of laboratory test workflow at metallurgical testing centers

    Directory of Open Access Journals (Sweden)

    F. Tošenovský

    2016-10-01

    Full Text Available The objective of the paper is to present a way to shorten the time required to perform laboratory tests of materials in metallurgy. The paper finds a relation between the time to perform a test of materials and the number of technicians carrying out the test. The relation can be used to optimize the number of technicians. The approach is based on probability theory, as the amount of material to be tested is unknown in advance, and uses powerful modelling techniques involving the generalized estimating equations.

  5. Quality assurance of laboratory work and clinical use of laboratory tests in general practice in norway: a survey.

    Science.gov (United States)

    Thue, Geir; Jevnaker, Marianne; Gulstad, Guri Andersen; Sandberg, Sverre

    2011-09-01

    Virtually all the general practices in Norway participate in the Norwegian Quality Improvement of Laboratory Services in Primary Care, NOKLUS. In order to assess and develop NOKLUS's services, it was decided to carry out an investigation in the largest participating group, general practices. In autumn 2008 a questionnaire was sent to all Norwegian general practices asking for feedback on different aspects of NOKLUS's main services: contact with medical laboratory technologists, sending of control materials, use and maintenance of practice-specific laboratory binders, courses, and testing of laboratory equipment. In addition, attitudes were elicited towards possible new services directed at assessing other technical equipment and clinical use of tests. Responses were received from 1290 of 1552 practices (83%). The great majority thought that the frequency of sending out control material should continue as at present, and they were pleased with the feedback reports and follow-up by the laboratory technologists in the counties. Even after many years of practical experience, there is still a need to update laboratory knowledge through visits to practices, courses, and written information. Practices also wanted quality assurance of blood pressure meters and spirometers, and many doctors wanted feedback on their use of laboratory tests. Services regarding quality assurance of point-of-care tests, guidance, and courses should be continued. Quality assurance of other technical equipment and of the doctor's clinical use of laboratory tests should be established as part of comprehensive quality assurance.

  6. The laboratory information float, time-based competition, and point-of-care testing.

    Science.gov (United States)

    Friedman, B A

    1994-01-01

    A new term, the laboratory information float, should be substituted for turnaround-time when evaluating the performance of the clinical laboratory because it includes the time necessary to make test results both available (ready to use) and accessible (easy to use) to clinicians ordering tests. The laboratory information float can be greatly reduced simply by telescoping the analytic phase of laboratory testing into the preanalytic phase. Significant costs are incurred by such a change, some of which can be reduced by developing a mobile clinical laboratory (sometimes referred to as a "lab-on-a-slab" or "rolling thunder") to transport the analytic devices directly to patient care units. The mobile clinical laboratory should be equipped with an integrated personal computer that can communicate continuously with the host laboratory information system and achieve some semblance of continuous flow processing despite test performance in point-of-care venues. Equipping clinicians with palmtop computers will allow the mobile clinician to access test results and order tests on the run. Such devices can be easily configured to operate in a passive mode, accessing relevant information automatically instead of forcing clinicians to query the laboratory information system periodically for the test results necessary to render care to their patients. The laboratory information float of the year 2,000 will surely be measured in minutes through the judicious deployment of relevant technology such as mobile clinical laboratories and palmtop computers.

  7. Automated cognitive testing of monkeys in social groups yields results comparable to individual laboratory-based testing.

    Science.gov (United States)

    Gazes, Regina Paxton; Brown, Emily Kathryn; Basile, Benjamin M; Hampton, Robert R

    2013-05-01

    Cognitive abilities likely evolved in response to specific environmental and social challenges and are therefore expected to be specialized for the life history of each species. Specialized cognitive abilities may be most readily engaged under conditions that approximate the natural environment of the species being studied. While naturalistic environments might therefore have advantages over laboratory settings for cognitive research, it is difficult to conduct certain types of cognitive tests in these settings. We implemented methods for automated cognitive testing of monkeys (Macaca mulatta) in large social groups (Field station) and compared the performance to that of laboratory-housed monkeys (Laboratory). The Field station animals shared access to four touch-screen computers in a large naturalistic social group. Each Field station subject had an RFID chip implanted in each arm for computerized identification and individualized assignment of cognitive tests. The Laboratory group was housed and tested in a typical laboratory setting, with individual access to testing computers in their home cages. Monkeys in both groups voluntarily participated at their own pace for food rewards. We evaluated performance in two visual psychophysics tests, a perceptual classification test, a transitive inference test, and a delayed matching-to-sample memory test. Despite the differences in housing, social environment, age, and sex, monkeys in the two groups performed similarly in all tests. Semi-free ranging monkeys living in complex social environments are therefore viable subjects for cognitive testing designed to take advantage of the unique affordances of naturalistic testing environments.

  8. Laboratory testing of the in-well vapor-stripping system

    International Nuclear Information System (INIS)

    Gilmore, T.J.; Francois, O.

    1996-03-01

    The Volatile organic Compounds-Arid Integrated Demonstration (VOC-Arid ID) was implemented by the US Department of Energy's (DOE's) Office of Technology Development to develop and test new technologies for the remediation of organic chemicals in the subsurface. One of the technologies being tested under the VOC-Arid ID is the in-well vapor-stripping system. The in-well vapor-stripping concept was initially proposed by researchers at Stanford University and is currently under development through a collaboration between workers at Stanford University and DOE's Pacific Northwest National Laboratory. The project to demonstrate the in-well vapor-stripping technology is divided into three phases: (1) conceptual model and computer simulation, (2) laboratory testing, and (3) field demonstration. This report provides the methods and results of the laboratory testing in which a full-scale replica was constructed and tested above ground in a test facility located at DOE's Hanford Site, Washington. The system is a remediation technology designed to preferentially extract volatile organic compounds (VOCs) from contaminated groundwater by converting them to a vapor phase

  9. US/Russian laboratory-to-laboratory program in materials protection, control and accounting at the RRC Kurchatov Institute

    International Nuclear Information System (INIS)

    Sukhoruchkin, V.; Roumiansev, A.; Shmelev, V.

    1996-01-01

    Six US DOE Laboratories are carrying out a program of cooperation with the Russian Research Center Kurchatov Institute (RRC KI) to improve the capabilities and facilities in nuclear material protection, control, and accounting (MPC ampersand A). In 1995, the primary emphasis of this program was the implementation of improved physical protection at a demonstration building at RRC KI, and the upgrading of the computerized MC ampersand A system, diagnostic instrumentation, and physical inventory procedures at a critical assembly within this building. Work continues in 1996 at the demonstration building but now also has begun at the two Kurchatov buildings which constitute the Central Storage Facility (CSF). At this facility, there will be upgrades in the physical inventory taking procedures, a test and evaluation of gamma-ray isotopic measurements, evaluations of nuclear material portal monitors and neutron-based measurement equipment as well as development of an improved computerized materials accounting system, implementation of bar code printing and reading equipment, development of tamper indicating device program, and substantial improvements in physical protection. Also, vulnerability assessments begun in 1995 are being extended to additional high priority facilities at Kurchatov

  10. The plane strain tests in the PROMETRA program

    International Nuclear Information System (INIS)

    Cazalis, B.; Desquines, J.; Carassou, S.; Le Jolu, T.; Bernaudat, C.

    2016-01-01

    A fuel cladding mechanical test, performed under conditions of plane strain deformation in the transverse direction of tube axis, was originally developed at Pennsylvania State University. It was decided to implement this original test within the PROMETRA program using the same experimental procedure and its optimization for a ring mechanical testing on plane strain conditions (PST tests) in hot cells laboratory. This paper presents a detailed description and an interpretation of the Plane Strain Tensile (PST) tests performed in the framework of the PROMETRA program on fresh and irradiated claddings. At first, the context of the PST tests is situated and the specificities of these tests implemented at CEA are justified. Indeed, a significant adjustment of the original experimental procedure is carried out in order to test the irradiated fuel cladding in the best possible conditions. Then, the tests results on fresh Zircaloy-4 and on irradiated Zircaloy-4, M5™ and ZIRLO ® specimens are gathered. The main analyses in support of these tests, such as metallographies, fractographic examinations and finite element simulations are detailed. Finally, a synthesis of the interpretation of the tests is proposed. The PST test seems only representative of plane strain fracture conditions when the test material is very ductile (fresh or high temperature or low hydride material like M5TM). However, it provides a relevant representation of the RIA rupture initiation which is observed in irradiated cladding resulting from hydride rim damage due to the strong irradiation of a fuel rod. - Highlights: • A plane strain mechanical test performed on fuel rod claddings is described. • The tests are performed in the framework of the French PROMETRA program. • Fresh Zircaloy-4 and irradiated Zircaloy-4, M5 and ZIRLO specimens are tested. • The main analyses in support of these tests are detailed. • A synthesis of the interpretation of the PST tests is proposed.

  11. The plane strain tests in the PROMETRA program

    Energy Technology Data Exchange (ETDEWEB)

    Cazalis, B., E-mail: bernard.cazalis@irsn.fr [Institut de Radioprotection et de Sûreté Nucléaire, IRSN/PSN-RES, F-13115 Saint-Paul Lez Durance BP3 (France); Desquines, J. [Institut de Radioprotection et de Sûreté Nucléaire, IRSN/PSN-RES, F-13115 Saint-Paul Lez Durance BP3 (France); Carassou, S.; Le Jolu, T. [Commissariat à l' Energie Atomique, CEA/DEN/DMN, F- 91191 Gif-sur-Yvette (France); Bernaudat, C. [Electricité de France, EDF/SEPTEN, F-69628 Villeurbanne (France)

    2016-04-15

    A fuel cladding mechanical test, performed under conditions of plane strain deformation in the transverse direction of tube axis, was originally developed at Pennsylvania State University. It was decided to implement this original test within the PROMETRA program using the same experimental procedure and its optimization for a ring mechanical testing on plane strain conditions (PST tests) in hot cells laboratory. This paper presents a detailed description and an interpretation of the Plane Strain Tensile (PST) tests performed in the framework of the PROMETRA program on fresh and irradiated claddings. At first, the context of the PST tests is situated and the specificities of these tests implemented at CEA are justified. Indeed, a significant adjustment of the original experimental procedure is carried out in order to test the irradiated fuel cladding in the best possible conditions. Then, the tests results on fresh Zircaloy-4 and on irradiated Zircaloy-4, M5™ and ZIRLO{sup ®} specimens are gathered. The main analyses in support of these tests, such as metallographies, fractographic examinations and finite element simulations are detailed. Finally, a synthesis of the interpretation of the tests is proposed. The PST test seems only representative of plane strain fracture conditions when the test material is very ductile (fresh or high temperature or low hydride material like M5TM). However, it provides a relevant representation of the RIA rupture initiation which is observed in irradiated cladding resulting from hydride rim damage due to the strong irradiation of a fuel rod. - Highlights: • A plane strain mechanical test performed on fuel rod claddings is described. • The tests are performed in the framework of the French PROMETRA program. • Fresh Zircaloy-4 and irradiated Zircaloy-4, M5 and ZIRLO specimens are tested. • The main analyses in support of these tests are detailed. • A synthesis of the interpretation of the PST tests is proposed.

  12. Lawrence Livermore National Laboratory laser-fusion program

    International Nuclear Information System (INIS)

    Ahlstrom, H.G.

    1982-01-01

    The goals of the Laser-Fusion Program at Lawrence Livermore National Laboratory are to produce well-diagnosed, high-gain, laser-driven fusion explosions in the laboratory and to exploit this capability for both military applications and for civilian energy production. In the past year we have made significant progress both theoretically and experimentally in our understanding of the laser interaction with both directly coupled and radiation-driven implosion targets and their implosion dynamics. We have made significant developments in fabricating the target structures. Data from the target experiments are producing important near-term physics results. We have also continued to develop attractive reactor concepts which illustrate ICF's potential as an energy producer

  13. Overview of the joint US/Russia surety program in the Sandia National Laboratories Cooperative Measures Program

    International Nuclear Information System (INIS)

    Smith, R.E.; Vorontsova, O.S.; Blinov, I.M.

    1998-02-01

    Sandia National Laboratories has initiated many joint research and development projects with the two premier Russian nuclear laboratories, VNIIEF and VNIITF, (historically known as Arzamas-16 and Chelyabinsk-70) in a wide spectrum of areas. One of the areas in which critical dialogue and technical exchange is continuing to take place is in the realm of system surety. Activities primarily include either safety or security methodology development, processes, accident environment analyses and testing, accident data-bases, assessments, and product design. Furthermore, a continuing dialog has been established between the organizations with regard to developing a better understanding of how risk is perceived and analyzed in Russia versus that in the US. The result of such efforts could reduce the risk of systems to incur accidents or incidents resulting in high consequences to the public. The purpose of this paper is to provide a current overview of the Sandia surety program and its various initiatives with the Russian institutes, with an emphasis on the program scope and rationale. The historical scope of projects will be indicated. A few specific projects will be discussed, along with results to date. The extension of the joint surety initiatives to other government and industry organizations will be described. This will include the current status of a joint Sandia/VNIIEF initiative to establish an International Surety Center for Energy Intensive and High Consequence Systems and Infrastructures

  14. LBNL Laboratory Directed Research and Development Program FY2016

    Energy Technology Data Exchange (ETDEWEB)

    Ho, D.

    2017-03-01

    The Berkeley Lab Laboratory Directed Research and Development Program FY2016 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the supported projects and summarizes their accomplishments. It constitutes a part of the LDRD program planning and documentation process that includes an annual planning cycle, project selection, implementation and review.

  15. Exploration of task performance tests in a physics laboratory

    Science.gov (United States)

    Liu, Dan; El Turkey, Houssein

    2017-11-01

    In this article, we investigate the implementation of task performance tests in an undergraduate physics laboratory. Two performance tests were carried out over two semesters using the task of building a DC circuit. The first implementation in Spring 2014 had certain concerns such as the privacy of students’ testing and their ‘trial and error’ attempts. These concerns were addressed in Fall 2015 through implementing a second performance test. The second implementation was administered differently but the content of the two tests was the same. We discuss the validity of both implementations and present the correlation (or lack of) between the time that students needed to complete the tests and their grades from a paper-based laboratory assessment method.

  16. Animal Investigation Program (AIP), A.I.P. summary report on and around the Nevada Test Site from 1982--1995

    International Nuclear Information System (INIS)

    Giles, K.R.

    1997-04-01

    This report describes the Animal Investigation Program conducted from 1982--1995 by the Environmental Protection Agency's (EPA's), Radiation and Indoor Environments National Laboratory (R and IE), formerly Radiation Sciences Laboratory-Las Vegas. This laboratory operates an environmental radiation monitoring program in the region surrounding the Nevada Test Site. The surveillance program was designed to measure levels and trends of radionuclides in animals on and around the Nevada Test Site to ascertain whether world-wide fallout, current radiation levels, and associated doses, to the general public were in compliance with existing radiation protection standards. The surveillance program additionally had the responsibility to take action to protect the health and well-being of the public in the event of any accidental release of radioactive contaminants. Comparison of the measurements and sample analysis results indicated that no significant amounts of biological radionuclides had been detected in the near offsite areas or on the NTS, except in animals drinking water that drains from tunnels in Area 12

  17. A survey of methods used for antimicrobial susceptibility testing in veterinary diagnostic laboratories in the United States.

    Science.gov (United States)

    Dargatz, David A; Erdman, Matthew M; Harris, Beth

    2017-09-01

    Antimicrobial resistance is a serious threat to animal and human health worldwide, requiring a collaborative, holistic approach. The U.S. Government has developed a national strategy to address antimicrobial resistance, with one component being to monitor antimicrobial resistance in agricultural settings. We developed a survey to collect information about antimicrobial susceptibility testing (AST) from the veterinary diagnostic laboratory community in the United States, assessing current practices and technologies and determining how AST information is shared. Of the 132 surveys administered, 52 (39%) were returned. Overall, responding laboratories conducted susceptibility tests on 98,788 bacterial isolates in 2014, with Escherichia coli being the most common pathogen tested across all animal species. The 2 most common AST methods employed were the disk diffusion method (71%) and the Sensititre platform broth microdilution system (59%). Laboratories primarily used the Clinical Laboratory Standards Institute (CLSI) VET-01 standard (69%) and the automatically calculated interpretations provided by the commercial AST systems (61%) for interpreting their AST data. Only 22% of laboratories published AST data on a periodic basis, usually via annual reports published on the laboratory's website or through peer-reviewed journals for specific pathogens. Our results confirm that disk diffusion and broth microdilution remain the standard AST methods employed by U.S. veterinary diagnostic laboratories, and that CLSI standards are commonly used for interpreting AST results. This information will help determine the most efficient standardized methodology for future surveillance. Furthermore, the current infrastructure within laboratories, once harmonized, will help provide a mechanism for conducting national surveillance programs.

  18. Laboratory services series: a master-slave manipulator maintenance program

    International Nuclear Information System (INIS)

    Jenness, R.G.; Hicks, R.E.; Wicker, C.D.

    1976-12-01

    The volume of master slave manipulator maintenance at Oak Ridge National Laboratory has necessitated the establishment of a repair facility and organization of a specially trained group of craftsmen. Emphasis on cell containment requires the use of manipulator boots and development of precise procedures for accomplishing the maintenance of 287 installed units. A very satisfactory computer programmed maintenance system has been established at the Laboratory to provide an economical approach to preventive maintenance

  19. Sandia National Laboratories California Waste Management Program Annual Report April 2011

    Energy Technology Data Exchange (ETDEWEB)

    Brynildson, Mark E. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2011-04-01

    The annual program report provides detailed information about all aspects of the Sandia National Laboratories, California (SNL/CA) Waste Management Program. It functions as supporting documentation to the SNL/CA Environmental Management System Program Manual. This annual program report describes the activities undertaken during the past year, and activities planned in future years to implement the Waste Management (WM) Program, one of six programs that supports environmental management at SNL/CA.

  20. Survey of in situ testing at underground laboratories with application to geologic disposal of spent fuel waste in crystalline rock

    International Nuclear Information System (INIS)

    Hardin, E.

    1992-04-01

    This report is intended for use in designing testing programs, or as backup material for the review of 'R and D 92' which will be the next three-year plan for spent fuel repository siting and characterization activities in Sweden. There are eight major topics, each of which is addressed in a chapter of around 2000 to 10000 words. The major topics are defined to capture the reasons for testing, in a way that limits overlap between chapters. Other goals of this report are to provide current information on recent or ongoing tests in crystalline rock, and to describe insights which are important but not obvious from the literature. No data are presented, but the conclusions of testing programs are summarized. The principal sources were reports (in English) produced by the laboratory projects particularly the Stripa Project (SKB), the Underground Research Laboratory in Canada (AECL), and the Grimsel Test Site in Switzerland (Nagra). Articles from refereed journals have been used in lieu of project literature where possible and appropriate. (au)

  1. Laboratory Directed Research and Development Program

    International Nuclear Information System (INIS)

    1994-02-01

    This report is compiled from annual reports submitted by principal investigators following the close of fiscal year 1993. This report describes the projects supported and summarizes their accomplishments. The program advances the Laboratory's core competencies, foundations, scientific capability, and permits exploration of exciting new opportunities. Reports are given from the following divisions: Accelerator and Fusion Research, Chemical Sciences, Earth Sciences, Energy and Environment, Engineering, Environment -- Health and Safety, Information and Computing Sciences, Life Sciences, Materials Sciences, Nuclear Science, Physics, and Structural Biology

  2. LDRD 2013 Annual Report: Laboratory Directed Research and Development Program Activities

    Energy Technology Data Exchange (ETDEWEB)

    Bookless, W. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2013-12-31

    This LDRD project establishes a research program led by Jingguang Chen, who has started a new position as a Joint Appointee between BNL and Columbia University as of FY2013. Under this project, Dr. Chen will establish a new program in catalysis science at BNL and Columbia University. The LDRD program will provide initial research funding to start research at both BNL and Columbia. At BNL, Dr. Chen will initiate laboratory research, including hiring research staff, and will collaborate with the existing BNL catalysis and electrocatalysis research groups. At Columbia, a subcontract to Dr. Chen will provide startup funding for his laboratory research, including initial graduate student costs. The research efforts will be linked under a common Catalysis Program in Sustainable Fuels. The overall impact of this project will be to strengthen the BNL catalysis science program through new linked research thrusts and the addition of an internationally distinguished catalysis scientist.

  3. Quality assurance practices in Europe: a survey of molecular genetic testing laboratories

    Science.gov (United States)

    Berwouts, Sarah; Fanning, Katrina; Morris, Michael A; Barton, David E; Dequeker, Elisabeth

    2012-01-01

    In the 2000s, a number of initiatives were taken internationally to improve quality in genetic testing services. To contribute to and update the limited literature available related to this topic, we surveyed 910 human molecular genetic testing laboratories, of which 291 (32%) from 29 European countries responded. The majority of laboratories were in the public sector (81%), affiliated with a university hospital (60%). Only a minority of laboratories was accredited (23%), and 26% was certified. A total of 22% of laboratories did not participate in external quality assessment (EQA) and 28% did not use reference materials (RMs). The main motivations given for accreditation were to improve laboratory profile (85%) and national recognition (84%). Nearly all respondents (95%) would prefer working in an accredited laboratory. In accredited laboratories, participation in EQA (Pquality assurance (Pquality implementation score (QIS), we showed that accredited laboratories (average score 92) comply better than certified laboratories (average score 69, Pquality indicators. We conclude that quality practices vary widely in European genetic testing laboratories. This leads to a potentially dangerous situation in which the quality of genetic testing is not consistently assured. PMID:22739339

  4. Trends in laboratory test volumes for Medicare Part B reimbursements, 2000-2010.

    Science.gov (United States)

    Shahangian, Shahram; Alspach, Todd D; Astles, J Rex; Yesupriya, Ajay; Dettwyler, William K

    2014-02-01

    Changes in reimbursements for clinical laboratory testing may help us assess the effect of various variables, such as testing recommendations, market forces, changes in testing technology, and changes in clinical or laboratory practices, and provide information that can influence health care and public health policy decisions. To date, however, there has been no report, to our knowledge, of longitudinal trends in national laboratory test use. To evaluate Medicare Part B-reimbursed volumes of selected laboratory tests per 10,000 enrollees from 2000 through 2010. Laboratory test reimbursement volumes per 10,000 enrollees in Medicare Part B were obtained from the Centers for Medicare & Medicaid Services (Baltimore, Maryland). The ratio of the most recent (2010) reimbursed test volume per 10,000 Medicare enrollees, divided by the oldest data (usually 2000) during this decade, called the volume ratio, was used to measure trends in test reimbursement. Laboratory tests with a reimbursement claim frequency of at least 10 per 10,000 Medicare enrollees in 2010 were selected, provided there was more than a 50% change in test reimbursement volume during the 2000-2010 decade. We combined the reimbursed test volumes for the few tests that were listed under more than one code in the Current Procedural Terminology (American Medical Association, Chicago, Illinois). A 2-sided Poisson regression, adjusted for potential overdispersion, was used to determine P values for the trend; trends were considered significant at P reimbursement volumes were electrolytes, digoxin, carbamazepine, phenytoin, and lithium, with volume ratios ranging from 0.27 to 0.64 (P reimbursement volumes were meprobamate, opiates, methadone, phencyclidine, amphetamines, cocaine, and vitamin D, with volume ratios ranging from 83 to 1510 (P reimbursement volumes increased for most of the selected tests, other tests exhibited statistically significant downward trends in annual reimbursement volumes. The observed

  5. Antiphospholipid Syndrome Laboratory Testing and Diagnostic Strategies

    Science.gov (United States)

    Ortel, Thomas L.

    2016-01-01

    The Antiphospholipid Syndrome (APS) is diagnosed in patients with recurrent thromboembolic events and/or pregnancy loss in the presence of persistent laboratory evidence for antiphospholipid antibodies. Diagnostic tests for the detection of antiphospholipid antibodies include laboratory assays that detect anticardiolipin antibodies, lupus anticoagulants, and anti-β2-glycoprotein I antibodies. These assays have their origins beginning more than sixty years ago, with the identification of the biologic false positive test for syphilis, the observation of ‘circulating anticoagulants’ in certain patients with systemic lupus erythematosus, the identification of cardiolipin as a key component in the serologic test for syphilis, and the recognition and characterization of a ‘cofactor’ for antibody binding to phospholipids. Although these assays have been used clinically for many years, there are still problems with the accurate diagnosis of patients with this syndrome. For example, lupus anticoagulant testing can be difficult to interpret in patients receiving anticoagulant therapy, but most patients with a thromboembolic event will already be anticoagulated before the decision to perform the tests has been made. In addition to understanding limitations of the assays, clinicians also need to be aware of which patients should be tested and not obtain testing on patients unlikely to have APS. New tests and diagnostic strategies are in various stages of development and should help improve our ability to accurately diagnose this important clinical disorder. PMID:22473619

  6. Testing and development of electric vehicle batteries for EPRI Electric Transportation Program

    Science.gov (United States)

    1985-11-01

    Argonne National Laboratory conducted an electric-vehicle battery testing and development program for the Electric Power Research Institute. As part of this program, eighteen battery modules previously developed by Johnson Controls, Inc. were tested. This type of battery (EV-2300 - an improved state-of-the-art lead-acid battery) was designed specifically for improved performance, range, and life in electric vehicles. In order to obtain necessary performance data, the batteries were tested under various duty cycles typical of normal service. This program, supported by the Electric Power Research Institute, consisted of three tasks: determination of the effect of cycle life vs peak power and rest period, determination of the impact of charge method on cycle life, and evaluation of the EV-2300 battery system. Two supporting studies were also carried out: one on thermal management of electric-vehicle batteries and one on enhanced utilization of active material in lead-acid batteries.

  7. Sandia National Laboratories, California Waste Management Program annual report : February 2009.

    Energy Technology Data Exchange (ETDEWEB)

    Brynildson, Mark E.

    2009-02-01

    The annual program report provides detailed information about all aspects of the Sandia National Laboratories, California (SNL/CA) Waste Management Program. It functions as supporting documentation to the SNL/CA Environmental Management System rogram Manual. This annual program report describes the activities undertaken during the past year, and activities planned in future years to implement the Waste Management (WM) Program, one of six programs that supports environmental management at SNL/CA.

  8. Evaluation of three oil spill laboratory dispersant effectiveness tests

    International Nuclear Information System (INIS)

    Sullivan, D.; Farlow, J.; Sahatjian, K.A.

    1993-01-01

    Chemical dispersants can be used to reduce the interfacial tension of floating oil slicks so that the oils disperse more rapidly into the water column and thus pose less of a threat to shorelines, birds, and marine mammals. The laboratory test currently specified in federal regulations to measure dispersant effectiveness is not especially easy or inexpensive, and generates a rather large quantity of oily waste water. This paper describes the results of an effort by the EPA to identify a more suitable laboratory dispersant effectiveness test. EPA evaluated three laboratory methods: the Revised Standard Dispersant Effectiveness Test currently used (and required by regulation) in the United States, the swirling flask test (developed by Environment Canada), and the IFP-dilution test (used in france and other European countries). Six test oils and three dispersants were evaluated; dispersants were applied to the oil at an average 1:10 ratio (dispersant to oil) for each of the three laboratory methods. Screening efforts were used to focus on the most appropriate oil/dispersant combination for detailed study. A screening criterion was established that required a combination that gave at least 20% effectiveness results. The selected combination turned out to be Prudhoe Bay crude oil and the dispersant Corexit 9527. This combination was also most likely to be encountered in US coastal waters. The EPA evaluation concluded that the three tests gave similar precision results, but that the swirling flask test was fastest, cheapest, simplest, and required least operator skill. Further, EPA is considering conducting the dispersant effectiveness test itself, rather than having data submitted by a dispersant manufacturer, and establishing an acceptability criterion (45% efficiency) which would have to be met before a dispersant could be placed on the Product Schedule of the National Contingency Plan (NCP)

  9. Inertial fusion research at Lawrence Livermore National Laboratory: program status and future applications

    International Nuclear Information System (INIS)

    Meier, W.R.; Hogan, W.J.

    1986-01-01

    The objectives of the Lawrence Livermore National Laboratory (LLNL) Laser Fusion Program are to understand and develop the science and technology required to utilize inertial confinement fusion (ICF) for both military and commercial applications. The results of recent experiments are described. We point out the progress in our laser studies, where we continue to develop and test the concepts, components, and materials for present and future laser systems. While there are many potential commercial applications of ICF, we limit our discussions to electric power production

  10. The BNL Accelerator Test Facility and experimental program

    International Nuclear Information System (INIS)

    Ben-Zvi, I.; State Univ. of New York, Stony Brook, NY

    1992-01-01

    The Accelerator Test Facility (ATF) at BNL is a users' facility for experiments in Accelerator and Beam Physics. The ATF provides high brightness electron beams and high-power laser pulses synchronized to the electron beam, suitable for studies of new methods of high-gradient acceleration and state-of-the-art Free-Electron Lasers. The electrons are produced by a laser photocathode rf gun and accelerated to 50 MeV by two traveling wave accelerator sections. The lasers include a 10 mJ, 10 ps ND:YAG laser and a 500 mJ, 10 to 100 ps C0 2 laser. A number of users from National Laboratories, universities and industry take part in experiments at the ATF. The experimental program includes various laser acceleration schemes, Free-Electron Laser experiments and a program on the development of high-brightness electron beams. The ATF's experimental program commenced in early 1991 at an energy of about 4 MeV. The full program, with 50 MeV and the high-power laser will begin operation this year

  11. The BNL Accelerator Test Facility and experimental program

    International Nuclear Information System (INIS)

    Ben-Zvi, I.; State Univ. of New York, Stony Brook, NY

    1991-01-01

    The Accelerator Test Facility (ATF) at BNL is a users' facility for experiments in Accelerator and Beam Physics. The ATF provides high brightness electron beams and high power laser pulses synchronized to the electron beam, suitable for studies of new methods of high gradient acceleration and state of the art free electron lasers. The electrons are produced by a laser photocathode rf gun and accelerated to 50 to 100 MeV by two traveling wave accelerator sections. The lasers include a 10 mJ, 10 ps Nd:YAG laser and a 100 mJ, 10 ps CO 2 laser. A number of users from National Laboratories, universities and industry take part in experiments at the ATF. The experimental program includes various acceleration schemes, Free-Electron Laser experiments and a program on the development of high brightness electron beams. The AFT's experimental program commenced in early 1991 at an energy of about 4 MeV. The full program, with 50 MeV and the High power laser will begin operation this year. 28 refs., 4 figs

  12. Radiographic testing at Lawrence Livermore National Laboratory

    International Nuclear Information System (INIS)

    Bossi, R.H.

    1982-01-01

    Radiographic testing is a nondestructive inspection technique which uses penetrating radiation. The Nondestructive Evaluation (NDE) Section at Lawrence Livermore National Laboratory has a broad spectrum of equipment and techniques for radiographic testing. These resources include low-energy vacuum systems, low- and mid-energy cabinet and cell radiographic systems, high-energy linear accelerators, portable x-ray machines and radioisotopes for radiographic inspections. For diagnostic testing the NDE Section also has real-time and flash radiographic equipment

  13. Waste certification program plan for Oak Ridge National Laboratory

    International Nuclear Information System (INIS)

    Kornegay, F.C.

    1996-09-01

    This document defines the waste certification program being developed for implementation at Oak Ridge National Laboratory (ORNL). The document describes the program structure, logic, and methodology for certification of ORNL wastes. The purpose of the waste certification program is to provide assurance that wastes are properly characterized and that the Waste Acceptance Criteria (WAC) for receiving facilities are met. The program meets the waste certification requirements outlined in U.S. Department of Energy (DOE) Order 5820.2A, Radioactive Waste Management, and ensures that 40 CFR documentation requirements for waste characterization are met for mixed (both radioactive and hazardous) and hazardous (including polychlorinated biphenyls) waste. Program activities will be conducted according to ORNL Level 1 document requirements

  14. EBR-2 [Experimental Breeder Reactor-2], IFR [Integral Fast Reactor] prototype testing programs

    International Nuclear Information System (INIS)

    Lehto, W.K.; Sackett, J.I.; Lindsay, R.W.; Planchon, H.P.; Lambert, J.D.B.

    1990-01-01

    The Experimental Breeder Reactor-2 (EBR-2) is a sodium cooled power reactor supplying about 20 MWe to the Idaho National Engineering Laboratory (INEL) grid and, in addition, is the key component in the development of the Integral Fast Reactor (IFR). EBR-2's testing capability is extensive and has seen four major phases: (1) demonstration of LMFBR power plant feasibility, (2) irradiation testing for fuel and material development. (3) testing the off-normal performance of fuel and plant systems and (4) operation as the IFR prototype, developing and demonstrating the IFR technology associated with fuel and plant design. Specific programs being carried out in support of the IFR include advanced fuels and materials development and component testing. This paper discusses EBR-2 as the IFR prototype and the associated testing programs. 29 refs

  15. Fermi National Acceleator Laboratory Annual Program Review 1992

    Energy Technology Data Exchange (ETDEWEB)

    Appel, Jeffrey A.; Jovanovic, Drasko; Pordes, Stephen [Fermilab

    1992-01-01

    This book is submitted as a written adjunct to the Annual DOE High Energy Physics Program Review of Fermilab, scheduled this year for March 31 - April 2, 1992. In it are described the functions and activities of the various Laboratory areas plus statements of plans and goals for the coming year.

  16. Fermi National Accelerator Laboratory Annual Program Review 1991

    Energy Technology Data Exchange (ETDEWEB)

    Appel, Jeffrey A. [Fermilab; Jovanovic, Drasko [Fermilab; Pordes, Stephen [Fermilab

    1991-01-01

    This book is submitted as a written adjunct to the Annual DOE High Energy Physics Program Review of Fermilab, scheduled this year for April 10-12, 1991. In it are described the functions and activities of the various Laboratory areas plus statements of plans and goals for the coming year.

  17. A Laboratory-Based Evaluation of Four Rapid Point-of-Care Tests for Syphilis

    Science.gov (United States)

    Causer, Louise M.; Kaldor, John M.; Fairley, Christopher K.; Donovan, Basil; Karapanagiotidis, Theo; Leslie, David E.; Robertson, Peter W.; McNulty, Anna M.; Anderson, David; Wand, Handan; Conway, Damian P.; Denham, Ian; Ryan, Claire; Guy, Rebecca J.

    2014-01-01

    Background Syphilis point-of-care tests may reduce morbidity and ongoing transmission by increasing the proportion of people rapidly treated. Syphilis stage and co-infection with HIV may influence test performance. We evaluated four commercially available syphilis point-of-care devices in a head-to-head comparison using sera from laboratories in Australia. Methods Point-of-care tests were evaluated using sera stored at Sydney and Melbourne laboratories. Sensitivity and specificity were calculated by standard methods, comparing point-of-care results to treponemal immunoassay (IA) reference test results. Additional analyses by clinical syphilis stage, HIV status, and non-treponemal antibody titre were performed. Non-overlapping 95% confidence intervals (CI) were considered statistically significant differences in estimates. Results In total 1203 specimens were tested (736 IA-reactive, 467 IA-nonreactive). Point-of-care test sensitivities were: Determine 97.3%(95%CI:95.8–98.3), Onsite 92.5%(90.3–94.3), DPP 89.8%(87.3–91.9) and Bioline 87.8%(85.1–90.0). Specificities were: Determine 96.4%(94.1–97.8), Onsite 92.5%(90.3–94.3), DPP 98.3%(96.5–99.2), and Bioline 98.5%(96.8–99.3). Sensitivity of the Determine test was 100% for primary and 100% for secondary syphilis. The three other tests had reduced sensitivity among primary (80.4–90.2%) compared to secondary syphilis (94.3–98.6%). No significant differences in sensitivity were observed by HIV status. Test sensitivities were significantly higher among high-RPR titre (RPR≥8) (range: 94.6–99.5%) than RPR non-reactive infections (range: 76.3–92.9%). Conclusions The Determine test had the highest sensitivity overall. All tests were most sensitive among high-RPR titre infections. Point-of-care tests have a role in syphilis control programs however in developed countries with established laboratory infrastructures, the lower sensitivities of some tests observed in primary syphilis suggest these would

  18. Laboratory Directed Research and Development Program FY 2008 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    editor, Todd C Hansen

    2009-02-23

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Berkeley Lab's research and the Laboratory Directed Research and Development (LDRD) program support DOE's Strategic Themes that are codified in DOE's 2006 Strategic Plan (DOE/CF-0010), with a primary focus on Scientific Discovery and Innovation. For that strategic theme, the Fiscal Year (FY) 2008 LDRD projects support each one of the three goals through multiple strategies described in the plan. In addition, LDRD efforts support the four goals of Energy Security, the two goals of Environmental Responsibility, and Nuclear Security (unclassified fundamental research that supports stockpile safety and nonproliferation programs). The LDRD program supports Office of Science strategic plans, including the 20-year Scientific Facilities Plan and the Office of Science Strategic Plan. The research also supports the strategic directions periodically under

  19. Laboratory Directed Research and Development Program FY 2008 Annual Report

    International Nuclear Information System (INIS)

    Hansen, Todd C.

    2009-01-01

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Berkeley Lab's research and the Laboratory Directed Research and Development (LDRD) program support DOE's Strategic Themes that are codified in DOE's 2006 Strategic Plan (DOE/CF-0010), with a primary focus on Scientific Discovery and Innovation. For that strategic theme, the Fiscal Year (FY) 2008 LDRD projects support each one of the three goals through multiple strategies described in the plan. In addition, LDRD efforts support the four goals of Energy Security, the two goals of Environmental Responsibility, and Nuclear Security (unclassified fundamental research that supports stockpile safety and nonproliferation programs). The LDRD program supports Office of Science strategic plans, including the 20-year Scientific Facilities Plan and the Office of Science Strategic Plan. The research also supports the strategic directions periodically under consideration and review by the

  20. 1986 environmental monitoring program report for the Idaho National Engineering Laboratory Site

    International Nuclear Information System (INIS)

    Hoff, D.L.; Chew, E.W.; Rope, S.K.

    1987-05-01

    This report presents onsite and offsite data collected in 1986 for the routine environmental monitoring program conducted by the Radiological and Environmental Sciences Laboratory (RESL) of the Department of Energy (DOE) at the Idaho National Engineering Laboratory (INEL) Site. The purpose of this routine program is to monitor radioactive and nonradioactive materials resulting from INEL Site operations which may reach the surrounding offsite environment and population. This report is prepared in accordance with the DOE requirements in draft DOE Order 5484.1 and is not intended to cover the numerous special environmental research programs being conducted at the INEL by RESL and others

  1. Status of the Virginia Power/DOE Cooperative Cask Testing/Demonstration Program: A video presentation

    International Nuclear Information System (INIS)

    McKinnon, M.A.; Creer, J.M.; Collantes, C.E.

    1990-01-01

    This paper is documentation of a video presentation and provides a brief summary of the Virginia power/US Department of Energy Cooperative Cask Testing/Demonstration Program. The program consists of two phases. The first phase has been completed and involved the unlicensed performance testing (heat transfer and shielding) of three metal spent fuel storage casks at the federally owned Idaho National Engineering Laboratory. The second phase is ongoing and consists of licensed demonstrations of standard casks from two different vendors and of one or two enhanced capacity casks. 6 refs., 1 tab

  2. Superconductor development program at Lawrence Livermore Laboratory

    International Nuclear Information System (INIS)

    Cornish, D.N.

    1978-01-01

    Winding of a Nb--Ti test coil at the Lawrence Livermore Laboratory is nearly complete. The conductor in this coil operates in a maximum field of 7.5 T and provides the 2-T field required by the Mirror Fusion Test Facility. Nb 3 Sn multifilamentary conductors, made using the ''bronze'' technique, appear capable of providing the higher fields needed by commercial reactors

  3. The passive autocatalytic recombiner test program at Sandia National Laboratories

    International Nuclear Information System (INIS)

    Blanchat, T.K.; Malliakos, A.

    1998-01-01

    Sandia National Laboratories (SNL) has developed systems and methodologies to measure the amount of hydrogen that can be depleted in a containment by a passive autocatalytic recombiner (PAR). Experiments were performed that determined the hydrogen depletion rate of a PAR in the presence of steam and also evaluated the effect of scale (number of cartridges) on the PAR performance at both low and high hydrogen concentrations. (author)

  4. 42 CFR 493.1453 - Condition: Laboratories performing high complexity testing; clinical consultant.

    Science.gov (United States)

    2010-10-01

    ... Condition: Laboratories performing high complexity testing; clinical consultant. The laboratory must have a... 42 Public Health 5 2010-10-01 2010-10-01 false Condition: Laboratories performing high complexity testing; clinical consultant. 493.1453 Section 493.1453 Public Health CENTERS FOR MEDICARE & MEDICAID...

  5. Hanford High-Level Waste Vitrification Program at the Pacific Northwest National Laboratory: technology development - annotated bibliography

    International Nuclear Information System (INIS)

    Larson, D.E.

    1996-09-01

    This report provides a collection of annotated bibliographies for documents prepared under the Hanford High-Level Waste Vitrification (Plant) Program. The bibliographies are for documents from Fiscal Year 1983 through Fiscal Year 1995, and include work conducted at or under the direction of the Pacific Northwest National Laboratory. The bibliographies included focus on the technology developed over the specified time period for vitrifying Hanford pretreated high-level waste. The following subject areas are included: General Documentation; Program Documentation; High-Level Waste Characterization; Glass Formulation and Characterization; Feed Preparation; Radioactive Feed Preparation and Glass Properties Testing; Full-Scale Feed Preparation Testing; Equipment Materials Testing; Melter Performance Assessment and Evaluations; Liquid-Fed Ceramic Melter; Cold Crucible Melter; Stirred Melter; High-Temperature Melter; Melter Off-Gas Treatment; Vitrification Waste Treatment; Process, Product Control and Modeling; Analytical; and Canister Closure, Decontamination, and Handling

  6. Evaluation of the defensive behavior of two honeybee ecotypes using a laboratory test

    Directory of Open Access Journals (Sweden)

    Cecilia Andere

    2002-01-01

    Full Text Available Honeybee defensive behavior is a useful selection criterion, especially in areas with Africanized honeybees (Apis mellifera L. In all genetic improvement programs the selected characters must be measured with precision, and because of this we evaluated a metabolic method for testing honeybee defensive behavior in the laboratory for its usefulness in distinguishing between honeybee ecotypes and selecting honeybees based on their level of defensive responses. Ten honeybee colonies were used, five having been produced by feral queens from a subtropical region supposedly colonized by Africanized honeybees and five by queens from a temperate region apparently colonized by European honeybees. We evaluate honeybee defensive behavior using a metabolic test based on oxygen consumption after stimulation with an alarm pheromone, measuring the time to the first response, time to maximum oxygen consumption, duration of activity, oxygen consumption at first response, maximum oxygen consumption and total oxygen consumption, colonies being ranked according to the values obtained for each variable. Significant (p < 0.05 differences were detected between ecotypes for each variable but for all variables the highest rankings were obtained for colonies of subtropical origin, which had faster and more intense responses. All variables were highly associated (p < 0.05. Total oxygen consumption was the best indicator of metabolic activity for defensive behavior because it combined oxygen consumption and the length of the response. This laboratory method may be useful for evaluating the defensive behavior of honey bees in genetic programs designed to select less defensive bees.

  7. Test plan for demonstration of Rapid Transuranic Monitoring Laboratory

    International Nuclear Information System (INIS)

    McIsaac, C.V.; Sill, C.W.; Gehrke, R.J.; Killian, E.W.; Watts, K.D.

    1993-06-01

    This plan describes tests to demonstrate the capability of the Rapid Transuranic Monitoring Laboratory (RTML) to monitor airborne alpha-emitting radionuclides and analyze soil, smear, and filter samples for alpha- and gamma-emitting radionuclides under field conditions. The RTML will be tested during June 1993 at a site adjacent to the Cold Test Pit at the Radioactive Waste Management Complex at the Idaho National Engineering Laboratory. Measurement systems installed in the RTML that will be demonstrated include two large-area ionization chamber alpha spectrometers, an x-ray/gamma-ray spectrometer, and four alpha continuous air monitors. Test objectives, requirements for data quality, experimental apparatus and procedures, and safety and logistics issues are described

  8. AUDILAB: a knowledge-based quality audit simulator for testing laboratories.

    Science.gov (United States)

    Brai, A; Garnerin, P

    1997-05-01

    In order to obtain an accreditation, a laboratory must be prepared to provide a point-by-point check of various activities against the chosen reference standard, both from a general point of view and in relation to details of application. This paper describes AUDILAB, a computerized simulator accessible by network, able to provide testing laboratories with realistic quality audits performed in a customized way. AUDILAB establishes a detailed list of strengths (compliance with corresponding requirements of established standards) and weaknesses (improvements needed for laboratory's accreditation). The standard used by AUDILAB is the EN 45001 "General criteria for the operation of testing laboratories". A preliminary validation has already been completed. AUDILAB became operational in September 1993.

  9. Accreditation of testing laboratories in CNEA (National Atomic Energy Commission)

    International Nuclear Information System (INIS)

    Piacquadio, N.H.; Casa, V.A.; Palacios, T.A.

    1993-01-01

    The recognition of the technical capability of a testing laboratory is carried out by Laboratory Accreditation Bodies as the result of a satisfactory evaluation and the systematic follow up of the certified qualification. In Argentina the creation of a National Center for the Accreditation of Testing Laboratories, as a first step to assess a National Accreditation System is currently projected. CNEA, as an institution involved in technological projects and in the development and production of goods and services, has adopted since a long time ago quality assurance criteria. One of their requirements is the qualification of laboratories. Due to the lack of a national system, a Committee for the Qualification of Laboratories was created jointly by the Research and Development and Nuclear Fuel Cycle Areas with the responsibility of planning and management of the system evaluation and the certification of the quality of laboratories. The experience in the above mentioned topics is described in this paper. (author)

  10. Approaches to quality management and accreditation in a genetic testing laboratory

    Science.gov (United States)

    Berwouts, Sarah; Morris, Michael A; Dequeker, Elisabeth

    2010-01-01

    Medical laboratories, and specifically genetic testing laboratories, provide vital medical services to different clients: clinicians requesting a test, patients from whom the sample was collected, public health and medical-legal instances, referral laboratories and authoritative bodies. All expect results that are accurate and obtained in an efficient and effective manner, within a suitable time frame and at acceptable cost. There are different ways of achieving the end results, but compliance with International Organization for Standardization (ISO) 15189, the international standard for the accreditation of medical laboratories, is becoming progressively accepted as the optimal approach to assuring quality in medical testing. We present recommendations and strategies designed to aid genetic testing laboratories with the implementation of a quality management system, including key aspects such as document control, external quality assessment, internal quality control, internal audit, management review, validation, as well as managing the human side of change. The focus is on pragmatic approaches to attain the levels of quality management and quality assurance required for accreditation according to ISO 15189, within the context of genetic testing. Attention is also given to implementing efficient and effective quality improvement. PMID:20720559

  11. Immediate needs for MQA testing at state secondary calibration laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Cline, R. [Radiation Instrument Calibration Laboratory, Springfield, IL (United States)

    1993-12-31

    The Calibration Laboratory attempts to provide services that satisfy the needs and requests for a variety of customers. New needs and requests have resulted in calibration of instrumentation outside the original laboratory designs. These tasks require several changes at the laboratory and a need for new support services, especially measurement quality assurance (MQA). The MQA tests are gamma (Cs-137) below 0.5 mrem (5{mu}Sv) per hour and x-ray kVp. Modification to the current gamma (Cs-137) MQA test is recommended because lower intensity fields are commonly measured.

  12. Immediate needs for MQA testing at state secondary calibration laboratories

    International Nuclear Information System (INIS)

    Cline, R.

    1993-01-01

    The Calibration Laboratory attempts to provide services that satisfy the needs and requests for a variety of customers. New needs and requests have resulted in calibration of instrumentation outside the original laboratory designs. These tasks require several changes at the laboratory and a need for new support services, especially measurement quality assurance (MQA). The MQA tests are gamma (Cs-137) below 0.5 mrem (5μSv) per hour and x-ray kVp. Modification to the current gamma (Cs-137) MQA test is recommended because lower intensity fields are commonly measured

  13. Errors in clinical laboratories or errors in laboratory medicine?

    Science.gov (United States)

    Plebani, Mario

    2006-01-01

    Laboratory testing is a highly complex process and, although laboratory services are relatively safe, they are not as safe as they could or should be. Clinical laboratories have long focused their attention on quality control methods and quality assessment programs dealing with analytical aspects of testing. However, a growing body of evidence accumulated in recent decades demonstrates that quality in clinical laboratories cannot be assured by merely focusing on purely analytical aspects. The more recent surveys on errors in laboratory medicine conclude that in the delivery of laboratory testing, mistakes occur more frequently before (pre-analytical) and after (post-analytical) the test has been performed. Most errors are due to pre-analytical factors (46-68.2% of total errors), while a high error rate (18.5-47% of total errors) has also been found in the post-analytical phase. Errors due to analytical problems have been significantly reduced over time, but there is evidence that, particularly for immunoassays, interference may have a serious impact on patients. A description of the most frequent and risky pre-, intra- and post-analytical errors and advice on practical steps for measuring and reducing the risk of errors is therefore given in the present paper. Many mistakes in the Total Testing Process are called "laboratory errors", although these may be due to poor communication, action taken by others involved in the testing process (e.g., physicians, nurses and phlebotomists), or poorly designed processes, all of which are beyond the laboratory's control. Likewise, there is evidence that laboratory information is only partially utilized. A recent document from the International Organization for Standardization (ISO) recommends a new, broader definition of the term "laboratory error" and a classification of errors according to different criteria. In a modern approach to total quality, centered on patients' needs and satisfaction, the risk of errors and mistakes

  14. Development of New, Low-Head Hydropower Turbine - Modeling & Laboratory Test DE-EE0005426

    Energy Technology Data Exchange (ETDEWEB)

    Krouse, Wayne [Hydro Green Energy, Westmont, IL (United States)

    2014-12-05

    Hydro Green Energy, LLC (HGE) will complete the design, fabrication and laboratory testing of a scaled, vertically stackable, low-head hydropower turbine called the Modular Bulb Turbine (MBT). HGE will also complete a summary report that includes the laboratory testing results and analysis of the tests. Project Goals: Design, model and test modular bulb turbine for installation in numerous HGE low-head hydropower projects at non-powered USACE dams. Project Results: The sub-scale prototype was tested successfully at a leading US hydraulic laboratory. Laboratory data results agreed well with predicted results from numerical modeling.

  15. Environmental and emergency response capabilities of Los Alamos Scientific Laboratory's radiological air sampling program

    International Nuclear Information System (INIS)

    Gunderson, T.C.

    1980-05-01

    Environmental and emergency response radiological air sampling capabilities of the Environmental Surveillance Group at Los Alamos Scientific Laboratory are described. The air sampling program provides a supplementary check on the adequacy of containment and effluent controls, determines compliance with applicable protection guides and standards, and assesses potential environmental impacts on site environs. It also allows evaluation of potential individual and total population doses from airborne radionuclides that may be inhaled or serve as a source of external radiation. The environmental program is sufficient in scope to detect fluctuations and long-term trends in atmospheric levels of radioactivity originating onsite. The emergency response capabilities are designed to respond to both onsite unplanned releases and atmospheric nuclear tests

  16. Hydrogen Field Test Standard: Laboratory and Field Performance

    Science.gov (United States)

    Pope, Jodie G.; Wright, John D.

    2015-01-01

    The National Institute of Standards and Technology (NIST) developed a prototype field test standard (FTS) that incorporates three test methods that could be used by state weights and measures inspectors to periodically verify the accuracy of retail hydrogen dispensers, much as gasoline dispensers are tested today. The three field test methods are: 1) gravimetric, 2) Pressure, Volume, Temperature (PVT), and 3) master meter. The FTS was tested in NIST's Transient Flow Facility with helium gas and in the field at a hydrogen dispenser location. All three methods agree within 0.57 % and 1.53 % for all test drafts of helium gas in the laboratory setting and of hydrogen gas in the field, respectively. The time required to perform six test drafts is similar for all three methods, ranging from 6 h for the gravimetric and master meter methods to 8 h for the PVT method. The laboratory tests show that 1) it is critical to wait for thermal equilibrium to achieve density measurements in the FTS that meet the desired uncertainty requirements for the PVT and master meter methods; in general, we found a wait time of 20 minutes introduces errors methods, respectively and 2) buoyancy corrections are important for the lowest uncertainty gravimetric measurements. The field tests show that sensor drift can become a largest component of uncertainty that is not present in the laboratory setting. The scale was calibrated after it was set up at the field location. Checks of the calibration throughout testing showed drift of 0.031 %. Calibration of the master meter and the pressure sensors prior to travel to the field location and upon return showed significant drifts in their calibrations; 0.14 % and up to 1.7 %, respectively. This highlights the need for better sensor selection and/or more robust sensor testing prior to putting into field service. All three test methods are capable of being successfully performed in the field and give equivalent answers if proper sensors without drift are

  17. Biometric identification devices -- Laboratory testing vs. real life

    International Nuclear Information System (INIS)

    Ahrens, J.S.

    1997-01-01

    For over fifteen years Sandia National Laboratories has been involved in laboratory testing of biometric identification devices. The key concept of biometric identification devices is the ability for the system to identify some unique aspect of the individual rather than some object a person may be carrying or some password they are required to know. Tests were conducted to verify manufacturer's performance claims, to determine strengths/weaknesses of devices, and to determine devices that meet the US Department of energy's needs. However, during recent field installation, significantly different performance was observed than was predicted by laboratory tests. Although most people using the device believed it operated adequately, the performance observed was over an order of magnitude worse than predicted. The search for reasons behind this gap between the predicted and the actual performance has revealed many possible contributing factors. As engineers, the most valuable lesson to be learned from this experience is the value of scientists and engineers with (1) common sense, (2) knowledge of human behavior, (3) the ability to observe the real world, and (4) the capability to realize the significant differences between controlled experiments and actual installations

  18. Modeling Canadian Quality Control Test Program for Steroid Hormone Receptors in Breast Cancer: Diagnostic Accuracy Study.

    Science.gov (United States)

    Pérez, Teresa; Makrestsov, Nikita; Garatt, John; Torlakovic, Emina; Gilks, C Blake; Mallett, Susan

    The Canadian Immunohistochemistry Quality Control program monitors clinical laboratory performance for estrogen receptor and progesterone receptor tests used in breast cancer treatment management in Canada. Current methods assess sensitivity and specificity at each time point, compared with a reference standard. We investigate alternative performance analysis methods to enhance the quality assessment. We used 3 methods of analysis: meta-analysis of sensitivity and specificity of each laboratory across all time points; sensitivity and specificity at each time point for each laboratory; and fitting models for repeated measurements to examine differences between laboratories adjusted by test and time point. Results show 88 laboratories participated in quality control at up to 13 time points using typically 37 to 54 histology samples. In meta-analysis across all time points no laboratories have sensitivity or specificity below 80%. Current methods, presenting sensitivity and specificity separately for each run, result in wide 95% confidence intervals, typically spanning 15% to 30%. Models of a single diagnostic outcome demonstrated that 82% to 100% of laboratories had no difference to reference standard for estrogen receptor and 75% to 100% for progesterone receptor, with the exception of 1 progesterone receptor run. Laboratories with significant differences to reference standard identified with Generalized Estimating Equation modeling also have reduced performance by meta-analysis across all time points. The Canadian Immunohistochemistry Quality Control program has a good design, and with this modeling approach has sufficient precision to measure performance at each time point and allow laboratories with a significantly lower performance to be targeted for advice.

  19. IRSN's radiological proficiency testings: a key for managing the quality of test laboratories in charge of the environmental radioactivity survey in France?

    Energy Technology Data Exchange (ETDEWEB)

    Ameon, R.; Gleizes, M.; Maulard, A.; Moine, J.; Vignaud, C. [Institute for Radioprotection and Nuclear Safety, IRSN (France)

    2014-07-01

    In France, many actors are involved in environmental monitoring (IRSN, operators of nuclear facilities, State services, approved air quality monitoring associations, environmental protection associations, private environmental laboratories...). The French National Network for Environmental Radioactivity Monitoring (RNM) federates all these entities. RNM brings together the environmental measurement results made in a regulatory framework on the French territory and make them available to the public through a web site. The quality of these measurements is guaranteed by subjecting the test laboratories to an approval procedure under the control of the French nuclear safety authority (ASN). The approval procedure includes administrative requirements (the laboratory shall meet ISO 17025 requirements) and the participation to proficiency testings (PT) provided by IRSN in order to demonstrate their technical competence. As approvals cover all components of the environment, the five-year PT program is defined on a combination of: - 6 types of environmental matrices: water, soil/sediments, biological matrices (tea, tobacco, fish, milk,...), aerosols on filters, gas-air (activated charcoal cartridge) and ambient air (RPL dosimeters), - 17 categories of radioactive measurements: g-emitters, gross a, gross b, {sup 3}H, {sup 14}C, {sup 90}Sr/{sup 90}Y, pure b-emitters, U isotopes and U content, Th isotopes, {sup 226}Ra and decay products, {sup 228}Ra and decay products, Pu/Am, {sup 129}I/{sup 131}I, noble gases, g-dose rate. Following ISO/CEI 17043 requirements, IRSN, as an accredited PT provider is in charge of: - Preparation and dispatch of test items, - Control of the homogeneity and stability of produced test items, - Determination of the assigned values, - Analysis of the results transmitted by participants in terms of relative bias, En number and z-score, - Publication of the report. PT program managed by IRSN groups 6 to 7 interlaboratory comparisons per year. Each of

  20. Hydrologic Resources Management Program and Underground Test Area Project FY2005 Progress Report

    International Nuclear Information System (INIS)

    Eaton, G F; Genetti, V; Hu, Q; Hudson, G B; Kersting, A B; Lindvall, R E; Moran, J E; Nimz, G J; Ramon, E C; Rose, T P; Shuller, L; Williams, R W; Zavarin, M; Zhao, P

    2007-01-01

    This report describes FY 2005 technical studies conducted by the Chemical Biology and Nuclear Science Division (CBND) at Lawrence Livermore National Laboratory (LLNL) in support of the Hydrologic Resources Management Program (HRMP) and the Underground Test Area Project (UGTA). These programs are administered by the U.S. Department of Energy, National Nuclear Security Administration, Nevada Site Office (NNSA/NSO) through the Defense Programs and Environmental Restoration Divisions, respectively. HRMP-sponsored work is directed toward the responsible management of the natural resources at the Nevada Test Site (NTS), enabling its continued use as a staging area for strategic operations in support of national security. UGTA-funded work emphasizes the development of an integrated set of groundwater flow and contaminant transport models to predict the extent of radionuclide migration from underground nuclear testing areas at the NTS. The report is organized on a topical basis and contains five chapters that highlight technical work products produced by CBND. However, it is important to recognize that most of this work involves collaborative partnerships with the other HRMP and UGTA contract organizations. These groups include the Energy and Environment Directorate at LLNL (LLNL-E and E), Los Alamos National Laboratory (LANL), the Desert Research Institute (DRI), the U.S. Geological Survey (USGS), Stoller-Navarro Joint Venture (SNJV), and Bechtel Nevada (BN)

  1. Los Alamos National Laboratory summary plan to fabricate mixed oxide lead assemblies for the fissile material disposition program

    International Nuclear Information System (INIS)

    Buksa, J.J.; Eaton, S.L.; Trellue, H.R.; Chidester, K.; Bowidowicz, M.; Morley, R.A.; Barr, M.

    1997-12-01

    This report summarizes an approach for using existing Los Alamos National Laboratory (Laboratory) mixed oxide (MOX) fuel-fabrication and plutonium processing capabilities to expedite and assure progress in the MOX/Reactor Plutonium Disposition Program. Lead Assembly MOX fabrication is required to provide prototypic fuel for testing in support of fuel qualification and licensing requirements. It is also required to provide a bridge for the full utilization of the European fabrication experience. In part, this bridge helps establish, for the first time since the early 1980s, a US experience base for meeting the safety, licensing, safeguards, security, and materials control and accountability requirements of the Department of Energy and Nuclear Regulatory Commission. In addition, a link is needed between the current research and development program and the production of disposition mission fuel. This link would also help provide a knowledge base for US regulators. Early MOX fabrication and irradiation testing in commercial nuclear reactors would provide a positive demonstration to Russia (and to potential vendors, designers, fabricators, and utilities) that the US has serious intent to proceed with plutonium disposition. This report summarizes an approach to fabricating lead assembly MOX fuel using the existing MOX fuel-fabrication infrastructure at the Laboratory

  2. Los Alamos National Laboratory summary plan to fabricate mixed oxide lead assemblies for the fissile material disposition program

    Energy Technology Data Exchange (ETDEWEB)

    Buksa, J.J.; Eaton, S.L.; Trellue, H.R.; Chidester, K.; Bowidowicz, M.; Morley, R.A.; Barr, M.

    1997-12-01

    This report summarizes an approach for using existing Los Alamos National Laboratory (Laboratory) mixed oxide (MOX) fuel-fabrication and plutonium processing capabilities to expedite and assure progress in the MOX/Reactor Plutonium Disposition Program. Lead Assembly MOX fabrication is required to provide prototypic fuel for testing in support of fuel qualification and licensing requirements. It is also required to provide a bridge for the full utilization of the European fabrication experience. In part, this bridge helps establish, for the first time since the early 1980s, a US experience base for meeting the safety, licensing, safeguards, security, and materials control and accountability requirements of the Department of Energy and Nuclear Regulatory Commission. In addition, a link is needed between the current research and development program and the production of disposition mission fuel. This link would also help provide a knowledge base for US regulators. Early MOX fabrication and irradiation testing in commercial nuclear reactors would provide a positive demonstration to Russia (and to potential vendors, designers, fabricators, and utilities) that the US has serious intent to proceed with plutonium disposition. This report summarizes an approach to fabricating lead assembly MOX fuel using the existing MOX fuel-fabrication infrastructure at the Laboratory.

  3. Multi-Sensor Testing for Automated Rendezvous and Docking Sensor Testing at the Flight Robotics Laboratory

    Science.gov (United States)

    Brewster, L.; Johnston, A.; Howard, R.; Mitchell, J.; Cryan, S.

    2007-01-01

    The Exploration Systems Architecture defines missions that require rendezvous, proximity operations, and docking (RPOD) of two spacecraft both in Low Earth Orbit (LEO) and in Low Lunar Orbit (LLO). Uncrewed spacecraft must perform automated and/or autonomous rendezvous, proximity operations and docking operations (commonly known as AR&D). The crewed missions may also perform rendezvous and docking operations and may require different levels of automation and/or autonomy, and must provide the crew with relative navigation information for manual piloting. The capabilities of the RPOD sensors are critical to the success of the Exploration Program. NASA has the responsibility to determine whether the Crew Exploration Vehicle (CEV) contractor proposed relative navigation sensor suite will meet the requirements. The relatively low technology readiness level of AR&D relative navigation sensors has been carried as one of the CEV Project's top risks. The AR&D Sensor Technology Project seeks to reduce the risk by the testing and analysis of selected relative navigation sensor technologies through hardware-in-the-loop testing and simulation. These activities will provide the CEV Project information to assess the relative navigation sensors maturity as well as demonstrate test methods and capabilities. The first year of this project focused on a series of"pathfinder" testing tasks to develop the test plans, test facility requirements, trajectories, math model architecture, simulation platform, and processes that will be used to evaluate the Contractor-proposed sensors. Four candidate sensors were used in the first phase of the testing. The second phase of testing used four sensors simultaneously: two Marshall Space Flight Center (MSFC) Advanced Video Guidance Sensors (AVGS), a laser-based video sensor that uses retroreflectors attached to the target vehicle, and two commercial laser range finders. The multi-sensor testing was conducted at MSFC's Flight Robotics Laboratory (FRL

  4. 'Experience with decommissioning of research and test reactors at Argonne National Laboratory'

    International Nuclear Information System (INIS)

    Bhattacharyya, S.K.; Yule, T.J.; Fellhauer, C.R.; Boing, L.E.

    2002-01-01

    A large number of research reactors around the world have reached the end of their useful operational life. Many of these are kept in a controlled storage mode awaiting decontamination and decommissioning (D and D). At Argonne National Laboratory located near Chicago in the United States of America, significant experience has been gained in the D and D of research and test reactors. These experiences span the entire range of activities in D and D - from planning and characterization of the facilities to the eventual disposition of all waste. A multifaceted D nd D program has been in progress at the Argonne National Laboratory - East site for nearly a decade. The program consists of three elements: - D and D of nuclear facilities on the site that have reached the end of their useful life; - Development and demonstrations of technologies that help in safe and cost effective D and D; - Presentation of training courses in D and D practices. Nuclear reactor facilities have been constructed and operated at the ANL-E site since the earliest days of nuclear power. As a result, a number of these early reactors reached end-of-life long before reactors on other sites and were ready for D and D earlier. They presented an excellent set of test beds on which D and D practices and technologies could be demonstrated in environments that were similar to commercial reactors, but considerably less hazardous. As shown, four reactor facilities, plutonium contaminated glove boxes and hot cells, a cyclotron facility and assorted other nuclear related facilities have been decommissioned in this program. The overall cost of the program has been modest relative to the cost of comparable projects undertaken both in the U.S. and abroad. The safety record throughout the program was excellent. Complementing the actual operations, a set of D and D technologies are being developed. These include robotic methods of tool handling and operation, chemical and laser decontamination techniques, sensors

  5. The testing effect for mediator final test cues and related final test cues in online and laboratory experiments.

    Science.gov (United States)

    Coppens, Leonora C; Verkoeijen, Peter P J L; Bouwmeester, Samantha; Rikers, Remy M J P

    2016-05-31

    The testing effect is the finding that information that is retrieved during learning is more often correctly retrieved on a final test than information that is restudied. According to the semantic mediator hypothesis the testing effect arises because retrieval practice of cue-target pairs (mother-child) activates semantically related mediators (father) more than restudying. Hence, the mediator-target (father-child) association should be stronger for retrieved than restudied pairs. Indeed, Carpenter (2011) found a larger testing effect when participants received mediators (father) than when they received target-related words (birth) as final test cues. The present study started as an attempt to test an alternative account of Carpenter's results. However, it turned into a series of conceptual (Experiment 1) and direct (Experiment 2 and 3) replications conducted with online samples. The results of these online replications were compared with those of similar existing laboratory experiments through small-scale meta-analyses. The results showed that (1) the magnitude of the raw mediator testing effect advantage is comparable for online and laboratory experiments, (2) in both online and laboratory experiments the magnitude of the raw mediator testing effect advantage is smaller than in Carpenter's original experiment, and (3) the testing effect for related cues varies considerably between online experiments. The variability in the testing effect for related cues in online experiments could point toward moderators of the related cue short-term testing effect. The raw mediator testing effect advantage is smaller than in Carpenter's original experiment.

  6. Web Environment for Programming and Control of a Mobile Robot in a Remote Laboratory

    Science.gov (United States)

    dos Santos Lopes, Maísa Soares; Gomes, Iago Pacheco; Trindade, Roque M. P.; da Silva, Alzira F.; de C. Lima, Antonio C.

    2017-01-01

    Remote robotics laboratories have been successfully used for engineering education. However, few of them use mobile robots to to teach computer science. This article describes a mobile robot Control and Programming Environment (CPE) and its pedagogical applications. The system comprises a remote laboratory for robotics, an online programming tool,…

  7. Obtaining patient test results from clinical laboratories: a survey of state law for pharmacists.

    Science.gov (United States)

    Witry, Matthew J; Doucette, William R

    2009-01-01

    To identify states with laws that restrict to whom clinical laboratories may release copies of laboratory test results and to describe how these laws may affect pharmacists' ability to obtain patient laboratory test results. Researchers examined state statutes and administrative codes for all 50 states and the District of Columbia at the University of Iowa Law Library between June and July 2007. Researchers also consulted with lawyers, state Clinical Laboratory Improvement Amendments officers, and law librarians. Laws relating to the study objective were analyzed. 34 jurisdictions do not restrict the release of laboratory test results, while 17 states have laws that restrict to whom clinical laboratories can send copies of test results. In these states, pharmacists will have to use alternative sources, such as physician offices, to obtain test results. Pharmacists must consider state law before requesting copies of laboratory test results from clinical laboratories. This may be an issue that state pharmacy associations can address to increase pharmacist access to important patient information.

  8. Immunohistochemistry practices of cytopathology laboratories: a survey of participants in the College of American Pathologists Nongynecologic Cytopathology Education Program.

    Science.gov (United States)

    Fischer, Andrew H; Schwartz, Mary R; Moriarty, Ann T; Wilbur, David C; Souers, Rhona; Fatheree, Lisa; Booth, Christine N; Clayton, Amy C; Kurtyz, Daniel F I; Padmanabhan, Vijayalakshmi; Crothers, Barbara A

    2014-09-01

    Immunohistochemistry (IHC) is important for cytology but poses special challenges because preanalytic conditions may differ from the conditions of IHC-positive controls. To broadly survey cytology laboratories to quantify preanalytic platforms for cytology IHC and identify problems with particular platforms or antigens. To discover how validation guidelines for HER2 testing have affected cytology. A voluntary survey of cytology IHC practices was sent to 1899 cytology laboratories participating in the College of American Pathologists Nongynecologic Cytopathology Education Program in the fall of 2009. A total of 818 laboratories (43%) responded to the survey by April 2010. Three hundred fourty-five of 791 respondents (44%) performed IHC on cytology specimens. Seventeen different fixation and processing platforms prior to antibody reaction were reported. A total of 59.2% of laboratories reported differences between the platforms for cytology specimens and positive controls, but most (155 of 184; 84%) did not alter antibody dilutions or antigen retrieval for cytology IHC. When asked to name 2 antibodies for which staining conditions differed between cytology and surgical samples, there were 18 responses listing 14 antibodies. A total of 30.6% of laboratories performing IHC offered HER2 testing before publication of the 2007 College of American Pathologists/American Society of Clinical Oncologists guidelines, compared with 33.6% afterward, with increased performance of testing by reference laboratories. Three laboratories validated a nonformalin HER2 platform. The platforms for cytology IHC and positive controls differ for most laboratories, yet conditions are uncommonly adjusted for cytology specimens. Except for the unsuitability of air-dried smears for HER2 testing, the survey did not reveal evidence of systematic problems with any antibody or platform.

  9. Development of a Laboratory Test Procedure to Evaluate Tack Coat Performance

    OpenAIRE

    YILDIRIM, Yetkin; SMIT, André de Fortier; KORKMAZ, Armagan

    2014-01-01

    A laboratory testing procedure is presented, the results of which may be used for determining the best combination of tack coat type, mixture type, and application rate to be applied in the field for optimum performance. Tack coat related performance results were determined from Hamburg wheel tracking and simple shear tests on laboratory prepared specimens. This study was undertaken to evaluate the shear strength performance of tack coats under laboratory-controlled conditions. The ...

  10. Institutional training programs for research personnel conducted by laboratory-animal veterinarians.

    Science.gov (United States)

    Dyson, Melissa C; Rush, Howard G

    2012-01-01

    Research institutions are required by federal law and national standards to ensure that individuals involved in animal research are appropriately trained in techniques and procedures used on animals. Meeting these requirements necessitates the support of institutional authorities; policies for the documentation and enforcement of training; resources to support and provide training programs; and high-quality, effective educational material. Because of their expertise, laboratory-animal veterinarians play an essential role in the design, implementation, and provision of educational programs for faculty, staff, and students in biomedical research. At large research institutions, provision of a training program for animal care and use personnel can be challenging because of the animal-research enterprise's size and scope. At the University of Michigan (UM), approximately 3,500 individuals have direct contact with animals used in research. We describe a comprehensive educational program for animal care and use personnel designed and provided by laboratory-animal veterinarians at UM and discuss the challenges associated with its implementation.

  11. Treatability study operational testing program and implementation plan for the Gunite and Associated Tanks at Oak Ridge National Laboratory, Oak Ridge, Tennessee

    International Nuclear Information System (INIS)

    1996-03-01

    This Treatability Study (TS) Operational Testing Program and Implementation Plan identifies operational testing to be performed to: (1) Demonstrate the technical feasibility of methods proposed for the removal of radiochemical sludge heels from the underground storage tanks located at Oak Ridge National Laboratory (ORNL), known as the Gunite and Associated Tanks (GAAT) Operable Unit (OU). (The bulk of the radiochemical waste, which was previously stored in the tanks, was removed during the 1980s, and only a sludge heel remains.) (2) Reduce the uncertainty in meeting the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) requirements for the GAAT OU. (3) Minimize the overall costs to accomplish the first two objectives. An initial Feasibility Study (FS) effort identified uncertainties in the evaluation of various alternatives for addressing the remediation of the GAAT OU. To support future decision making, the US. Department of Energy is performing a TS to identify cost-effective remediation approaches for the GAAT OU by providing information to reduce cost and technical uncertainty and better define acceptable remediation strategies. The testing activities will be initially conducted in a nonradioactive environment at the Tanks Technology Cold Test Facility (TTCTF) at ORNL. This will permit the design and initial performance testing and training activities to be completed while minimizing the risk, employee exposure, and costs associated with the testing effort. The component design and functional testing and initial system performance testing will be completed in the TTCTF. After the component and initial system performance testing have been completed, the operations testing will continue in the North Tank Farm (NTF). This testing has an associated higher cost and risk, but is necessary to provide results for actual waste heel removal

  12. An innovative approach for testing bioinformatics programs using metamorphic testing

    Directory of Open Access Journals (Sweden)

    Liu Huai

    2009-01-01

    Full Text Available Abstract Background Recent advances in experimental and computational technologies have fueled the development of many sophisticated bioinformatics programs. The correctness of such programs is crucial as incorrectly computed results may lead to wrong biological conclusion or misguide downstream experimentation. Common software testing procedures involve executing the target program with a set of test inputs and then verifying the correctness of the test outputs. However, due to the complexity of many bioinformatics programs, it is often difficult to verify the correctness of the test outputs. Therefore our ability to perform systematic software testing is greatly hindered. Results We propose to use a novel software testing technique, metamorphic testing (MT, to test a range of bioinformatics programs. Instead of requiring a mechanism to verify whether an individual test output is correct, the MT technique verifies whether a pair of test outputs conform to a set of domain specific properties, called metamorphic relations (MRs, thus greatly increases the number and variety of test cases that can be applied. To demonstrate how MT is used in practice, we applied MT to test two open-source bioinformatics programs, namely GNLab and SeqMap. In particular we show that MT is simple to implement, and is effective in detecting faults in a real-life program and some artificially fault-seeded programs. Further, we discuss how MT can be applied to test programs from various domains of bioinformatics. Conclusion This paper describes the application of a simple, effective and automated technique to systematically test a range of bioinformatics programs. We show how MT can be implemented in practice through two real-life case studies. Since many bioinformatics programs, particularly those for large scale simulation and data analysis, are hard to test systematically, their developers may benefit from using MT as part of the testing strategy. Therefore our work

  13. 1/3-scale model testing program

    International Nuclear Information System (INIS)

    Yoshimura, H.R.; Attaway, S.W.; Bronowski, D.R.; Uncapher, W.L.; Huerta, M.; Abbott, D.G.

    1989-01-01

    This paper describes the drop testing of a one-third scale model transport cask system. Two casks were supplied by Transnuclear, Inc. (TN) to demonstrate dual purpose shipping/storage casks. These casks will be used to ship spent fuel from DOEs West Valley demonstration project in New York to the Idaho National Engineering Laboratory (INEL) for long term spent fuel dry storage demonstration. As part of the certification process, one-third scale model tests were performed to obtain experimental data. Two 9-m (30-ft) drop tests were conducted on a mass model of the cask body and scaled balsa and redwood filled impact limiters. In the first test, the cask system was tested in an end-on configuration. In the second test, the system was tested in a slap-down configuration where the axis of the cask was oriented at a 10 degree angle with the horizontal. Slap-down occurs for shallow angle drops where the primary impact at one end of the cask is followed by a secondary impact at the other end. The objectives of the testing program were to (1) obtain deceleration and displacement information for the cask and impact limiter system, (2) obtain dynamic force-displacement data for the impact limiters, (3) verify the integrity of the impact limiter retention system, and (4) examine the crush behavior of the limiters. This paper describes both test results in terms of measured deceleration, post test deformation measurements, and the general structural response of the system

  14. Interference by pralidoxime (PAM) salts in clinical laboratory tests.

    Science.gov (United States)

    Nagase, Sumika; Kohguchi, Katsunori; Tohyama, Kaoru; Watanabe, Mikio; Iwatani, Yoshinori

    2013-02-01

    Drugs sometimes alter the results of clinical laboratory tests. We examined the effects of pralidoxime (PAM) salts, a medicine used to treat organophosphorus poisoning, on clinical laboratory test results for the first time. The effects of PAM salts on glucose (GLU) measurements were examined using a point-of-care testing (POCT) meter, four self-monitoring of blood glucose (SMBG) meters, and two biochemical autoanalyzers. The effects of PAM salts on other clinical tests were also evaluated. The addition of PAM iodide or potassium iodide, but not of PAM chloride or potassium chloride, to blood samples increased the GLU values measured by one POCT meter and 4 SMBG meters using the enzyme electrode (hydrogen peroxidase or oxygen electrode) method. On the other hand, PAM iodide or PAM chloride, but not KI or KCl, affected the values measured at 340 nm by an autoanalyzer using absorption spectrophotometry in 8 of 14 clinical laboratory tests. The absorption spectrum of PAM changed from 294 to 338 nm due to the reaction between PAM and the alkaline buffer, a component of the measuring reagents. PAM iodide increases the GLU values measured by the enzyme electrode method, and PAM salts affected the values measured at 340 nm by absorption spectrophotometry in many other clinical test items. Copyright © 2012 Elsevier B.V. All rights reserved.

  15. Plutonium immobilization project development and testing quality assurance program description - February 1999

    International Nuclear Information System (INIS)

    MacLean, L. M.; Ziemba, J.

    1999-01-01

    Lawrence Livermore National Laboratory Immobilization Development and Testing organization (LLNL ID and T) is a Participant in the Plutonium Immobilization Project (PIP). The LLNL D and T has lead responsibilities for form characterization and qualification, ceramic form development, process/equipment development with plutonium, and process systems testing and validation for both conversion and immobilization. This work must be performed in accordance with the graded approach of a Quality Assurance (QA) Program. A QA Program has been developed at LLNL to meet the requirements of the DOE/MD Quality Assurance Requirements. The LLNL QA Program consists of a Quality Assurance Program Description (QAPD) and Quality Implementing Procedures. These documents interface and are a subset of the overall PIP QA Program Documents. The PIP QA Program is described in the PIP ID and T QA Plan, PIP QAPD, and QA Procedures. Other Participant Organizations also must document and describe their PIP compliant QA Programs in a QAPD and implementing procedures. The purpose of this LLNL QAPD is to describe the organization, management processes, QA Controls for Grading, functional responsibilities, levels of authority, and interfaces for those managing, performing, and assessing the adequacy of work

  16. Proficiency testing schemes as a quality rating in industrial hygiene laboratories

    Directory of Open Access Journals (Sweden)

    Marek Dobecki

    2016-04-01

    Full Text Available This publication presents the principles of organization, implementation, assessment and exploitation of proficiency testing results in the work environmental laboratory based on basic requirements included in standard PN-EN ISO/IEC 17043 and ISO 13528. The basis for the proper functioning of the laboratory is to use and observe the basic requirements for the competence to carry out the tests and the guidelines on ensuring reliable and accurate results, specified e.g., according to the guidelines described in the standard PN-EN ISO/IEC 17043. The confirmation of the laboratory competence is the obtained accreditation. To obtain this certificate several conditions, including proficiency testing (PT should be met. The main aspects of this paper is to show the role of proficiency testing in the process of assuring a properly functioning quality system in the laboratory. The accreditation requirements, the types of proficiency testing schemes, methods of statistical analysis and interpretation of results are also discussed by the authors. Med Pr 2016;67(2:267–283

  17. Duplicate laboratory test reduction using a clinical decision support tool.

    Science.gov (United States)

    Procop, Gary W; Yerian, Lisa M; Wyllie, Robert; Harrison, A Marc; Kottke-Marchant, Kandice

    2014-05-01

    Duplicate laboratory tests that are unwarranted increase unnecessary phlebotomy, which contributes to iatrogenic anemia, decreased patient satisfaction, and increased health care costs. We employed a clinical decision support tool (CDST) to block unnecessary duplicate test orders during the computerized physician order entry (CPOE) process. We assessed laboratory cost savings after 2 years and searched for untoward patient events associated with this intervention. This CDST blocked 11,790 unnecessary duplicate test orders in these 2 years, which resulted in a cost savings of $183,586. There were no untoward effects reported associated with this intervention. The movement to CPOE affords real-time interaction between the laboratory and the physician through CDSTs that signal duplicate orders. These interactions save health care dollars and should also increase patient satisfaction and well-being.

  18. Comprehensive resurvey program to prevent radiological incidents at a national laboratory

    International Nuclear Information System (INIS)

    Lipton, W.V.; Hunckler, C.A.

    1978-01-01

    A comprehensive resurvey program in a general purpose research building at Argonne National Laboratory is being implemented. The program was designed to prevent radiological incidents by increasing the awareness of Health Physics personnel of radiological hazards, initiating corrective actions, and providing information for improving routine survey schedules, and for establishing manpower requirements. The following aspects of the program are described: scheduling, surveys, records, follow-up, and statistics

  19. Comparison of Rapid Malaria Test and Laboratory Microscopy ...

    African Journals Online (AJOL)

    Michael Horsfall

    ABSTRACT: Blood samples collected from 272 volunteers in two communities of Bayelsa State in the Niger. Delta area were investigated for falciparum malaria parasite using the rapid test based on the detection of soluble antigen and laboratory microscopy test. The data showed that out of the 272 samples collected, ...

  20. Mars Science Laboratory Rover System Thermal Test

    Science.gov (United States)

    Novak, Keith S.; Kempenaar, Joshua E.; Liu, Yuanming; Bhandari, Pradeep; Dudik, Brenda A.

    2012-01-01

    On November 26, 2011, NASA launched a large (900 kg) rover as part of the Mars Science Laboratory (MSL) mission to Mars. The MSL rover is scheduled to land on Mars on August 5, 2012. Prior to launch, the Rover was successfully operated in simulated mission extreme environments during a 16-day long Rover System Thermal Test (STT). This paper describes the MSL Rover STT, test planning, test execution, test results, thermal model correlation and flight predictions. The rover was tested in the JPL 25-Foot Diameter Space Simulator Facility at the Jet Propulsion Laboratory (JPL). The Rover operated in simulated Cruise (vacuum) and Mars Surface environments (8 Torr nitrogen gas) with mission extreme hot and cold boundary conditions. A Xenon lamp solar simulator was used to impose simulated solar loads on the rover during a bounding hot case and during a simulated Mars diurnal test case. All thermal hardware was exercised and performed nominally. The Rover Heat Rejection System, a liquid-phase fluid loop used to transport heat in and out of the electronics boxes inside the rover chassis, performed better than predicted. Steady state and transient data were collected to allow correlation of analytical thermal models. These thermal models were subsequently used to predict rover thermal performance for the MSL Gale Crater landing site. Models predict that critical hardware temperatures will be maintained within allowable flight limits over the entire 669 Sol surface mission.

  1. Chemical Pathology Laboratory Tests in Pregnancy | Bolarin ...

    African Journals Online (AJOL)

    Thus, chemical pathology laboratory investigative test results during normal healthy pregnancy show significant differences from the normal reference intervals or ranges (i.e. non-pregnant woman's reference intervals or ranges) thereby causing misinterpretation as inappropriate or odd. This wrong interpretation of the ...

  2. Sandia National Laboratories, California Hazardous Materials Management Program annual report : February 2009.

    Energy Technology Data Exchange (ETDEWEB)

    Brynildson, Mark E.

    2009-02-01

    The annual program report provides detailed information about all aspects of the Sandia National Laboratories, California (SNL/CA) Hazardous Materials Management Program. It functions as supporting documentation to the SNL/CA Environmental anagement ystem Program Manual. This program annual report describes the activities undertaken during the past year, and activities planned in future years to implement the Hazardous Materials Management Program, one of six programs that supports environmental management at SNL/CA.

  3. Application of flexible scope in large testing laboratories

    Directory of Open Access Journals (Sweden)

    Carina Di Candia

    2011-04-01

    Full Text Available According as the international definition of Flexible Scope, a laboratory must demonstrate face with the accreditation body that it has the knowledge, experience and competence to work within the full range of its flexible scope, as well as possessing suitable laboratory environments and equipment. The laboratory must also demonstrate that it has a management system in place that can control its proposed approach while continuing to comply with the requirements of ISO 17025:2005. In case of UKAS (Unites Kingdom Accreditation Service, prior to offering accreditation for flexible scope they must have a high degree of confidence that the staff are technically competent and that the management system controlling certain key processes as development, review, validation and authorization.LATU apply these requirements since 2004 as "Unified Tests". Until this date, LATU was doing the same type of tests in different materials departments using different equipment, personal, and testing quality control. In order to that were defined cross disciplinary groups to analyze this topic approaching in personal competence and quality control tests improvement, and resource's decrease. For example, LATU has the Unified Test Tensile Strength accredited by UKAS in: corrugated and solid fiberboard, paper board, linerboard, cork plugs, plastic bags, plastic sheeting, paper, woven fabrics, plastic woven bags and woven plastic. As a result of the Unified Tests was generated a general unified manage procedure with unified criteria's, responsibilities and actions. Was written a unique testing procedure not only with the actual flexible scope and the flexibilities limits but also the compliance requirements of ISO 17025 and the accreditations body methodology. We could decrease the amount of documentation to control. Was defined the methodology and implemented periodicaly internal inter comparisons between departments in order to valid the unified tests and has a unique

  4. Evaluating Laboratory Performance on Point-of-Care Glucose Testing with Six Sigma Metric for 151 Institutions in China.

    Science.gov (United States)

    Fei, Yang; Wang, Wei; He, Falin; Zhong, Kun; Wang, Zhiguo

    2015-10-01

    The aim of this study was to use Six Sigma(SM) (Motorola Trademark Holdings, Libertyville, IL) techniques to analyze the quality of point-of-care (POC) glucose testing measurements quantitatively and to provide suggestions for improvement. In total, 151 laboratories in China were included in this investigation in 2014. Bias and coefficient of variation were collected from an external quality assessment and an internal quality control program, respectively, for POC glucose testing organized by the National Center for Clinical Laboratories. The σ values and the Quality Goal Index were used to evaluate the performance of POC glucose meters. There were 27, 30, 57, and 37 participants in the groups using Optium Xceed™ (Abbott Diabetes Care, Alameda, CA), Accu-Chek(®) Performa (Roche, Basel, Switzerland), One Touch Ultra(®) (Abbott), and "other" meters, respectively. The median of the absolute value of percentage difference varied among different lots and different groups. Among all the groups, the Abbott One Touch Ultra group had the smallest median of absolute value of percentage difference except for lot 201411, whereas the "other" group had the largest median in all five lots. More than 85% of participate laboratories satisfied the total allowable error (TEa) requirement in International Organization for Standardization standard 15197:2013, and 85.43% (129/151) of laboratories obtained intralaboratory coefficient of variations less than 1/3TEa. However, Six Sigma techniques suggested that 41.72% (63/151) to 65.56% (99/151) of the laboratories needed to improve their POC glucose testing performance, in either precision, trueness, or both. Laboratories should pay more attention on the practice of POC glucose testing and take actions to improve their performance. Only in this way can POC glucose testing really function well in clinical practice.

  5. Fermi National Accelerator Laboratory Annual Program Review 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-01-01

    This book is submitted as a written adjunct to the 1993 Annual DOE High Energy Physics Program Review of Fermilab, scheduled for March 31-April 3. In it are described the functions and activities of the various Laboratory Divisions and Sections plus statements of plans and goals for the coming year. The Review Committee, as this goes to press, consists of·

  6. System Quality Management in Software Testing Laboratory that Chooses Accreditation

    Directory of Open Access Journals (Sweden)

    Yanet Brito R.

    2013-12-01

    Full Text Available The evaluation of software products will reach full maturity when executed by the scheme and provides third party certification. For the validity of the certification, the independent laboratory must be accredited for that function, using internationally recognized standards. This brings with it a challenge for the Industrial Laboratory Testing Software (LIPS, responsible for testing the products developed in Cuban Software Industry, define strategies that will permit it to offer services with a high level of quality. Therefore it is necessary to establish a system of quality management according to NC-ISO/IEC 17025: 2006 to continuously improve the operational capacity and technical competence of the laboratory, with a view to future accreditation of tests performed. This article discusses the process defined in the LIPS for the implementation of a Management System of Quality, from the current standards and trends, as a necessary step to opt for the accreditation of the tests performed.

  7. Laboratory test for ice adhesion strength using commercial instrumentation.

    Science.gov (United States)

    Wang, Chenyu; Zhang, Wei; Siva, Adarsh; Tiea, Daniel; Wynne, Kenneth J

    2014-01-21

    A laboratory test method for evaluating ice adhesion has been developed employing a commercially available instrument normally used for dynamic mechanical analysis (TA RSA-III). This is the first laboratory ice adhesion test that does not require a custom-built apparatus. The upper grip range of ∼10 mm is an enabling feature that is essential for the test. The method involves removal of an ice cylinder from a polymer coating with a probe and the determination of peak removal force (Ps). To validate the test method, the strength of ice adhesion was determined for a prototypical glassy polymer, poly(methyl methacrylate). The distance of the probe from the PMMA surface has been identified as a critical variable for Ps. The new test provides a readily available platform for investigating fundamental surface characteristics affecting ice adhesion. In addition to the ice release test, PMMA coatings were characterized using DSC, DCA, and TM-AFM.

  8. Underground Nuclear Testing Program, Nevada Test Site

    International Nuclear Information System (INIS)

    1975-09-01

    The Energy Research and Development Administration (ERDA) continues to conduct an underground nuclear testing program which includes tests for nuclear weapons development and other tests for development of nuclear explosives and methods for their application for peaceful uses. ERDA also continues to provide nuclear explosive and test site support for nuclear effects tests sponsored by the Department of Defense. This Supplement extends the Environmental Statement (WASH-1526) to cover all underground nuclear tests and preparations for tests of one megaton (1 MT) or less at the Nevada Test Site (NTS) during Fiscal Year 1976. The test activities covered include numerous continuing programs, both nuclear and non-nuclear, which can best be conducted in a remote area. However, if nuclear excavation tests or tests of yields above 1 MT or tests away from NTS should be planned, these will be covered by separate environmental statements

  9. A national clinical quality program for Veterans Affairs catheterization laboratories (from the Veterans Affairs clinical assessment, reporting, and tracking program).

    Science.gov (United States)

    Maddox, Thomas M; Plomondon, Mary E; Petrich, Megan; Tsai, Thomas T; Gethoffer, Hans; Noonan, Gregory; Gillespie, Brian; Box, Tamara; Fihn, Stephen D; Jesse, Robert L; Rumsfeld, John S

    2014-12-01

    A "learning health care system", as outlined in a recent Institute of Medicine report, harnesses real-time clinical data to continuously measure and improve clinical care. However, most current efforts to understand and improve the quality of care rely on retrospective chart abstractions complied long after the provision of clinical care. To align more closely with the goals of a learning health care system, we present the novel design and initial results of the Veterans Affairs (VA) Clinical Assessment, Reporting, and Tracking (CART) program-a national clinical quality program for VA cardiac catheterization laboratories that harnesses real-time clinical data to support clinical care and quality-monitoring efforts. Integrated within the VA electronic health record, the CART program uses a specialized software platform to collect real-time patient and procedural data for all VA patients undergoing coronary procedures in VA catheterization laboratories. The program began in 2005 and currently contains data on 434,967 catheterization laboratory procedures, including 272,097 coronary angiograms and 86,481 percutaneous coronary interventions, performed by 801 clinicians on 246,967 patients. We present the initial data from the CART program and describe 3 quality-monitoring programs that use its unique characteristics-procedural and complications feedback to individual labs, coronary device surveillance, and major adverse event peer review. The VA CART program is a novel approach to electronic health record design that supports clinical care, quality, and safety in VA catheterization laboratories. Its approach holds promise in achieving the goals of a learning health care system. Published by Elsevier Inc.

  10. Pilot instrumentation of a Superpave test section at the Kansas Accelerated Testing laboratory

    Science.gov (United States)

    2003-04-01

    Two Superpave test sections were constructed at the Kansas Accelerated Testing Laboratory (K-ATL) with 12.5 mm (2 in) nominal maximum size Superpave mixture (SM-2A) with varying percentages (15 and 30 percent) of river sand. A 150 kN (34 kip) tandem ...

  11. Learning of Musculoskeletal Ligament Stress Testing in a Gross Anatomy Laboratory

    Science.gov (United States)

    Krause, David A.; Youdas, James W.; Hollman, John H.

    2011-01-01

    Human anatomy in physical therapy programs is a basic science course serving as a foundation for subsequent clinical courses. Integration of anatomy with a clinical emphasis throughout a curriculum provides opportunities for reinforcement of previously learned material. Considering the human cadaver laboratory as a fixed cost to our program, we…

  12. Test of user- and system programs coded in real time languages - requirements on program language and testing tool

    International Nuclear Information System (INIS)

    Hertlin, J.; Mackert, M.

    1979-01-01

    In the present paper the functions are presented, which should be part of a test system for user programs in a higher treat time programming language, taking into account time sequences and competitive processes. As can be shown by the problem of testing, use of higher level real time programming languages renders the task of program development essentially easier, however performance of test procedures without appropriate test systems is very difficult. After the presentation of notions and methods for the testing of programs, general requirements on testing tools are described and the test system functions for a program test, beeing uncritical with respect to time, are placed together. Thereby, for every individual function, the interface between the test system, the program under test, and the residual program-generation system (compiler, binder, operating system, delay-time system, and loader) is given too. For the time-critical test, a series of desirable functions are described, which can be implemented with acceptable expense. (orig.) [de

  13. Utility of laboratory testing for the diagnosis of Hymenoptera venom allergy.

    Science.gov (United States)

    Vachová, Martina; Panzner, Petr; Malkusová, Ivana; Hanzlíková, Jana; Vlas, Tomáš

    2016-05-01

    A diagnosis of Hymenoptera venom allergy is based on clinical history and the results of skin tests and/or laboratory methods. To analyze the utility of available laboratory tests in diagnosing Hymenoptera venom allergy. Ninety-five patients with Hymenoptera venom allergy with a history of bee (35) or wasp (60) anaphylactic sting reaction and positive skin test with bee or wasp venom were included in this analysis. Specific immunoglobulin E (to bee venom extract, wasp venom extract, available recombinant molecules, and a basophil activation test with venom extracts were assessed in all the patients. Test sensitivity and specificity were calculated by using standard threshold values; then, receiver operating characteristic curve analysis was performed to compute optimal threshold values. Also, statistical analysis of the utility of different combinations of laboratory tests was performed. The optimal threshold values were revealed to be the following: 1.0 kIU/L for bee venom extract (sensitivity, 97.14%; specificity, 100%), 0.35 kIU/L for rApi m 1 (sensitivity, 68.57%; specificity, 100%), 1.22 kIU/L for wasp venom extract (sensitivity, 88.33%; specificity, 95.45%), 0.7 kIU/L for rVes v 5 (sensitivity, 86.67%; specificity, 95.45%), 1.0 kIU/L for rVes v 1 (sensitivity, 56.67%; specificity, 95.45%), 6.5% for basophil activation test with bee venom extract (sensitivity, 80%; specificity, 95.45%), and 4.5% for basophil activation test with wasp venom extract (sensitivity, 91.53%; specificity, 95.45%). The best test combinations were found to be the following: bee venom extract plus rApi m 1 (sensitivity, 97.14%; specificity, 95.45%) in bee and either wasp venom extract plus rVes v 5, or rVes v 5 plus rVes v 1 (both sensitivity, 98.33%; specificity, 95.45%) in patients with wasp venom allergy. Our analysis confirmed that currently used laboratory tests represent effective tools in diagnosing Hymenoptera venom allergy. Moreover, our probabilistic approach offered another

  14. Laboratory compliance with the American Society of Clinical Oncology/College of American Pathologists human epidermal growth factor receptor 2 testing guidelines: a 3-year comparison of validation procedures.

    Science.gov (United States)

    Dyhdalo, Kathryn S; Fitzgibbons, Patrick L; Goldsmith, Jeffery D; Souers, Rhona J; Nakhleh, Raouf E

    2014-07-01

    The American Society of Clinical Oncology/College of American Pathologists (ASCO/CAP) published guidelines in 2007 regarding testing accuracy, interpretation, and reporting of results for HER2 studies. A 2008 survey identified areas needing improved compliance. To reassess laboratory response to those guidelines following a full accreditation cycle for an updated snapshot of laboratory practices regarding ASCO/CAP guidelines. In 2011, a survey was distributed with the HER2 immunohistochemistry (IHC) proficiency testing program identical to the 2008 survey. Of the 1150 surveys sent, 977 (85.0%) were returned, comparable to the original survey response in 2008 (757 of 907; 83.5%). New participants submitted 124 of 977 (12.7%) surveys. The median laboratory accession rate was 14,788 cases with 211 HER2 tests performed annually. Testing was validated with fluorescence in situ hybridization in 49.1% (443 of 902) of the laboratories; 26.3% (224 of 853) of the laboratories used another IHC assay. The median number of cases to validate fluorescence in situ hybridization (n = 40) and IHC (n = 27) was similar to those in 2008. Ninety-five percent concordance with fluorescence in situ hybridization was achieved by 76.5% (254 of 332) of laboratories for IHC(-) findings and 70.4% (233 of 331) for IHC(+) cases. Ninety-five percent concordance with another IHC assay was achieved by 71.1% (118 of 168) of the laboratories for negative findings and 69.6% (112 of 161) of the laboratories for positive cases. The proportion of laboratories interpreting HER2 IHC using ASCO/CAP guidelines (86.6% [798 of 921] in 2011; 83.8% [605 of 722] in 2008) remains similar. Although fixation time improvements have been made, assay validation deficiencies still exist. The results of this survey were shared within the CAP, including the Laboratory Accreditation Program and the ASCO/CAP panel revising the HER2 guidelines published in October 2013. The Laboratory Accreditation Program checklist was

  15. Evaluating the effectiveness of an online medical laboratory technician program.

    Science.gov (United States)

    Hansen-Suchy, Kara

    2011-01-01

    The purpose of this study was to analyze the effectiveness of an online medical laboratory technician program in the academic preparation and development of laboratory professionals. A semi-quantitative comparative research design was used. Several factors were considered in this evaluation. Academic outcomes between online and campus medical laboratory technician (MLT) students was determined by comparing overall and categorical scores on certification exams as well as first time pass rate. Certification exam scores and first time pass rates were also compared to national norms when possible to do so. Demographic data, including age and experience were compared. Additionally, learning styles were assessed to determine if there was a correlation to overall GPA and MLT GPA and if learning styles could be used to predict successful completion of an online Associates of Applied Science. The research was conducted at an academic university located in the mountain west United States. Participants consisted of online and campus students enrolled in a Medical Laboratory Technician program that graduated with their Associate of Applied Science degree between the years 2007-2009. Results of these years were also compared to graduates from 2004-2006 in the same program. Certification performance and first time pass rates were the major outcomes measured. Age and experience were correlated. Online learning styles and GPA were also compared to successful degree completion. The researcher found no significant difference in certification performance with regard to total and categorical scores, and first time pass rates between campus and online MLT students. Online students were slightly older and had more experience working in a laboratory in some capacity. Correlation studies showed significant positive correlation between learning styles, GPA, and successful completion of an Associate of Applied Science degree. When registry scores were compared to the prior cohort of online

  16. USAF Summer Research Program - 1995 High School Apprenticeship Program Final Reports, Volume 14, Rome Laboratory

    National Research Council Canada - National Science Library

    Moore, Gary

    1995-01-01

    The United States Air Force High School Apprenticeship Program's (USAF HSAP) purpose is to place outstanding high school students whose interests are in the areas of mathematics, engineering, and science to work in a laboratory environment...

  17. A suitability study of the fission product phantom and the bottle manikin absorption phantom for calibration of in vivo bioassay equipment for the DOELAP accreditation testing program

    International Nuclear Information System (INIS)

    Olsen, P.C.; Lynch, T.P.

    1991-08-01

    Pacific Northwest laboratory (PNL) conducted an intercomparison study of the Fission Product phantom and the bottle manikin absorption (BOMAB) phantom for the US Department of Energy (DOE) to determine the consistency of calibration response of the two phantoms and their suitability for certification and use under a planned bioassay laboratory accreditation program. The study was initiated to determine calibration factors for both types of phantoms and to evaluate the suitability of their use in DOE Laboratory Accreditation Program (DOELAP) round-robin testing. The BOMAB was found to be more appropriate for the DOELAP testing program. 9 refs., 9 figs., 9 tabs

  18. The Case for Laboratory Developed Procedures

    Directory of Open Access Journals (Sweden)

    Karen L. Kaul MD, PhD

    2017-07-01

    Full Text Available An explosion of knowledge and technology is revolutionizing medicine and patient care. Novel testing must be brought to the clinic with safety and accuracy, but also in a timely and cost-effective manner, so that patients can benefit and laboratories can offer testing consistent with current guidelines. Under the oversight provided by the Clinical Laboratory Improvement Amendments, laboratories have been able to develop and optimize laboratory procedures for use in-house. Quality improvement programs, interlaboratory comparisons, and the ability of laboratories to adjust assays as needed to improve results, utilize new sample types, or incorporate new mutations, information, or technologies are positive aspects of Clinical Laboratory Improvement Amendments oversight of laboratory-developed procedures. Laboratories have a long history of successful service to patients operating under Clinical Laboratory Improvement Amendments. A series of detailed clinical examples illustrating the quality and positive impact of laboratory-developed procedures on patient care is provided. These examples also demonstrate how Clinical Laboratory Improvement Amendments oversight ensures accurate, reliable, and reproducible testing in clinical laboratories.

  19. Educational ultrasound nondestructive testing laboratory.

    Science.gov (United States)

    Genis, Vladimir; Zagorski, Michael

    2008-09-01

    The ultrasound nondestructive evaluation (NDE) of materials course was developed for applied engineering technology students at Drexel University's Goodwin College of Professional Studies. This three-credit, hands-on laboratory course consists of two parts: the first part with an emphasis on the foundations of NDE, and the second part during which ultrasound NDE techniques are utilized in the evaluation of parts and materials. NDE applications are presented and applied through real-life problems, including calibration and use of the latest ultrasonic testing instrumentation. The students learn engineering and physical principles of measurements of sound velocity in different materials, attenuation coefficients, material thickness, and location and dimensions of discontinuities in various materials, such as holes, cracks, and flaws. The work in the laboratory enhances the fundamentals taught during classroom sessions. This course will ultimately result in improvements in the educational process ["The greater expectations," national panel report, http://www.greaterexpectations.org (last viewed February, 2008); R. M. Felder and R. Brent "The intellectual development of Science and Engineering Students. Part 2: Teaching to promote growth," J. Eng. Educ. 93, 279-291 (2004)] since industry is becoming increasingly reliant on the effective application of NDE technology and the demand on NDE specialists is increasing. NDE curriculum was designed to fulfill levels I and II NDE in theory and training requirements, according to American Society for Nondestructive Testing, OH, Recommended Practice No. SNT-TC-1A (2006).

  20. NDE Technology Development Program for Non-Visual Volumetric Inspection Technology; Sensor Effectiveness Testing Report

    Energy Technology Data Exchange (ETDEWEB)

    Moran, Traci L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Larche, Michael R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Denslow, Kayte M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Glass, Samuel W. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2017-08-31

    The Pacific Northwest National Laboratory (PNNL) located in Richland, Washington, hosted and administered Sensor Effectiveness Testing that allowed four different participants to demonstrate the NDE volumetric inspection technologies that were previously demonstrated during the Technology Screening session. This document provides a Sensor Effectiveness Testing report for the final part of Phase I of a three-phase NDE Technology Development Program designed to identify and mature a system or set of non-visual volumetric NDE technologies for Hanford DST primary liner bottom inspection. Phase I of the program will baseline the performance of current or emerging non-visual volumetric NDE technologies for their ability to detect and characterize primary liner bottom flaws, and identify candidate technologies for adaptation and maturation for Phase II of the program.

  1. Package testing capabilities at the Pacific Northwest Laboratory

    International Nuclear Information System (INIS)

    Taylor, J.M.

    1993-01-01

    The purpose of this paper is to describe the package testing capabilities at the Pacific Northwest Laboratory (PNL). In the past all of the package testing that was performed at PNL was done on prototype or mocked up radioactive material packaging. Presently, we are developing the capability to perform testing on non-radioactive material packaging. The testing on the non-radioactive material packaging will be done to satisfy the new performance oriented packaging requirements (DOT Docket HM-181, 1991). This paper describes the equipment used to perform the performance oriented packaging tests and also describes some testing capability for testing radioactive material packaging

  2. Plutonium immobilization project development and testing technical project office quality assurance program description

    International Nuclear Information System (INIS)

    Gould, T.H.; MacLean, L.M.; Ziemba, J.M.

    1999-01-01

    The Plutonium Immobilization Project (PIP) is one of several fissile materials disposition projects managed by the Department of Energy (DOE) Office of Fissile Materials Disposition (OFMD). The PIP is expected to evolve from the current Development and Testing (D and T) effort, to design, to construction, and finally to operations. Overall management and technical management of the D and T effort resides at the Lead Laboratory, Lawrence Livermore National Laboratory (LLNL), through the LLNL Manager, Fissile Materials Disposition Program (FMDP). Day to day project activities are managed by the D and T Technical Project Office (TPO), which reports to the LLNL Manager, FMDP. The D and T TPO consists of the Technical Manager, the TPO Quality Assurance (QA) Program Manager, and TPO Planning and Support Staff. This Quality Assurance Program Description (QAPD) defines the QA policies and controls that will be implemented by these TPO personnel in their management of D and T activities. This QAPD is consistent with and responsive to the Department of Energy Fissile Materials Disposition Program Quality Assurance Requirements Document (FMDP QARD). As the Project and upper level requirement's documents evolve, this QAPD will be updated as necessary to accurately define and describe the QA Program and Management of the PIP. The TPO has a policy that all development and testing activities be planned, performed and assessed in accordance with its customer's requirements, needs and expectations, and with a commitment to excellence and continuous improvement. The TPO QAPD describes implementation requirements which, when completed, will ensure that the project development and testing activities conform to the appropriate QA requirements. For the program to be effective, the TPO QA Program Manager will ensure that each site participating in D and T activities has developed a QAPD, which meets the customer's requirements, and has a designated quality leader in place. These customer

  3. Laboratory evaluation of three dual rapid diagnostic tests for HIV and syphilis in China and Nigeria.

    Science.gov (United States)

    Yin, Yue-Ping; Ngige, Evelyn; Anyaike, Chukwuma; Ijaodola, Gbenga; Oyelade, Taiwo A; Vaz, Rui Gama; Newman, Lori M; Chen, Xiang-Sheng

    2015-06-01

    To determine the laboratory-based performance and operational characteristics of three dual rapid diagnostic tests (RDTs) for testing HIV and syphilis. Three dual RDTs (SD Bioline, Chembio, and MedMira) were evaluated using 1514 serum specimens archived at laboratories or collected from clinics in China and Nigeria to determine sensitivity and specificity, with 95% confidence intervals. Concordance of testing results read by two technicians, stability of testing results read at two time points, and test operation characteristics were also assessed. All three of the evaluated RDTs gave excellent performance with a combined sensitivity ranging from 99.0%-99.6% for HIV and 98.3%-99.0% for syphilis, and a combined specificity ranging from 97.9%-99.0% for HIV and 97.2%-99.6% for syphilis. Concordance of testing results between two technicians and stability of testing results read within and one hour past the recommended reading period showed excellent agreement, with Kappa greater than or equal to 0.98. All the tests were found to be very or fairly easy to use and easy to interpret the results. Further evaluations of these dual RDTs with whole blood in field settings, and more studies on the implication of introduction of these tests in HIV and syphilis control programs are needed. Copyright © 2015. Published by Elsevier Ireland Ltd.

  4. Recent Improvements to the Acoustical Testing Laboratory at the NASA Glenn Research Center

    Science.gov (United States)

    Podboy, Devin M.; Mirecki, Julius H.; Walker, Bruce E.; Sutliff, Daniel L.

    2014-01-01

    The Acoustical Testing Laboratory (ATL) consists of a 27 by 23 by 20 ft (height) convertible hemi/anechoic chamber and separate sound-attenuating test support enclosure. Absorptive fiberglass wedges in the test chamber provide an anechoic environment down to 100 Hz. A spring-isolated floor system affords vibration isolation above 3 Hz. These specifications, along with very low design background levels, enable the acquisition of accurate and repeatable acoustical measurements on test articles that produce very low sound pressures. Removable floor wedges allow the test chamber to operate in either a hemi-anechoic or anechoic configuration, depending on the size of the test article and the specific test being conducted. The test support enclosure functions as a control room during normal operations. Recently improvements were accomplished in support of continued usage of the ATL by NASA programs including an analysis of the ultra-sonic characteristics. A 3 dimensional traverse system inside the chamber was utilized for acquiring acoustic data for these tests. The traverse system drives a linear array of 13, 1/4"-microphones spaced 3" apart (36" span). An updated data acquisition system was also incorporated into the facility.

  5. Sandia Laboratories technical capabilities: auxiliary capabilities

    International Nuclear Information System (INIS)

    1978-09-01

    The primary responsibility of the environmental health function is the evaluation and control of hazardous materials and conditions. The evaluation and control of toxic materials, nonionizing radiation such as laser beams and microwaves, and ionizing radiation such as from radiation machines and radioactive sources, are examples of the activities of environmental health programs. A chemical laboratory is operated for the analysis of toxic and radioactive substances and for the bioassay program to provide an index of internal exposure of personnel to toxic and radioactive materials. Instrumentation support and development is provided for environmental health activities. A dosimetry program is maintained to measure personnel exposure to external ionizing radiation. A radiation counting laboratory is maintained. Reentry safety control and effluent documentation support are provided for underground nuclear tests at the Nevada Test Site. A radiation training program is provided for laboratory personnel which covers all areas of radiation protection, from working with radioactive materials to radiation-producing machines. The information science activity functions within the framework of Sandia Laboratories' technical libraries. Information science is oriented toward the efficient dissemination of information to technical and administrative personnel. Computerized systems are used to collect, process and circulate books, reports, and other literature. Current-awareness, reference, translation, and literature-search services are also provided

  6. Onsite assessments for the Department of Energy Laboratory Accreditation Program

    International Nuclear Information System (INIS)

    McMahan, K.L.

    1992-01-01

    For Department of Energy (DOE) facilities, compliance with DOE Order 5480.11 became a requirement in January 1989. One of the requirements of this Order is that personal external dosimetry programs be accredited under the Department of Energy's Laboratory Accreditation Program (DOELAP) in Personnel Dosimetry. The accreditation process, from the facility's perspective, is two-fold: dosimeters must meet performance criteria in radiation categories appropriate for each facility, and personnel administering and carrying out the program must demonstrate good operating practices. The DOELAP onsite assessment is designed to provide an independent evaluation of the latter

  7. Laboratory test of an APS-based sun sensor prototype

    Science.gov (United States)

    Rufino, Giancarlo; Perrotta, Alessandro; Grassi, Michele

    2017-11-01

    This paper deals with design and prototype development of an Active Pixel Sensor - based miniature sun sensor and a laboratory facility for its indoor test and calibration. The miniature sun sensor is described and the laboratory test facility is presented in detail. The major focus of the paper is on tests and calibration of the sensor. Two different calibration functions have been adopted. They are based, respectively, on a geometrical model, which has required least-squares optimisation of system physical parameters estimates, and on neural networks. Calibration results are presented for the above solutions, showing that accuracy in the order of 0.01° has been achieved. Neural calibration functions have attained better performance thanks to their intrinsic auto-adaptive structure.

  8. Shielded analytical laboratory activities supporting waste isolation programs

    International Nuclear Information System (INIS)

    McCown, J.J.

    1985-08-01

    The Shielded Analytical Laboratory (SAL) is a six cell manipulator-equipped facility which was built in 1962 as an addition to the 325 Radiochemistry Bldg. in the 300 Area at Hanford. The facility provides the capability for handling a wide variety of radioactive materials and performing chemical dissolutions, separations and analyses on nuclear fuels, components, waste forms and materials from R and D programs

  9. Performance testing of UK personal dosimetry laboratories

    CERN Document Server

    Marshall, T O

    1985-01-01

    The proposed Ionising Radiations Regulations will require all UK personal dosimetry laboratories that monitor classified personnel to be approved for personal dosimetry by the Health and Safety Executive. It is suggested that these approvals should be based on general and supplementary criteria published by the British Calibration Service (BCS) for laboratory approval for the provision of personal dosimetry services. These criteria specify certain qualitative requirements and also indicate the need for regular tests of performance to be carried out to ensure constancy of dosimetric standards. This report concerns the latter. The status of the BCS criteria is discussed and the need for additional documents to cover new techniques and some modifications to existing documents is indicated. A means is described by which the technical performance of laboratories, concerned with personal monitoring for external radiations, can be assessed, both initially and ongoing. The costs to establish the scheme and operate it...

  10. Comparability between NQA-1 and the QA programs for analytical laboratories within the nuclear industry and EPA hazardous waste laboratories

    International Nuclear Information System (INIS)

    English, S.L.; Dahl, D.R.

    1989-01-01

    There is increasing cooperation between the Department of Energy (DOE), Department of Defense (DOD), and the Environmental Protection Agency (EPA) in the activities associated with monitoring and clean-up of hazardous wastes. Pacific Northwest Laboratory (PNL) examined the quality assurance/quality control programs that the EPA requires of the private sector when performing routine analyses of hazardous wastes to confirm how or if the requirements correspond with PNL's QA program based upon NQA-1. This paper presents the similarities and differences between NQA-1 and the QA program identified in ASTM-C1009-83, Establishing a QA Program for Analytical Chemistry Laboratories within the Nuclear Industry; EPA QAMS-005/80, Interim Guidelines and Specifications for Preparing Quality Assurance Project Plans, which is referenced in Statements of Work for CERCLA analytical activities; and Chapter 1 of SW-846, which is used in analyses of RCRA samples. The EPA QA programs for hazardous waste analyses are easily encompassed within an already established NQA-1 QA program. A few new terms are introduced and there is an increased emphasis upon the QC/verification, but there are many of the same basic concepts in all the programs

  11. Text Messaging Improves Participation in Laboratory Testing in Adolescent Liver Transplant Patients.

    Science.gov (United States)

    McKenzie, Rebecca B; Berquist, William E; Foley, Megan A; Park, K T; Windsheimer, Jered E; Litt, Iris F

    In solid organ transplant patients, non-participation in all aspects of the medical regimen is a prevalent problem associated with adverse consequences particularly in the adolescent and young adult (AYA) age group. This study is the first to evaluate the feasibility, utility and impact of a text messaging (TM) intervention to improve participation in laboratory testing in adolescent liver transplant patients. AYA patients, aged 12 to 21 years, were recruited for a prospective pilot trial evaluating a TM intervention delivered over a 1-year period. The intervention involved automated TM reminders with feedback administered according to a prescribed laboratory testing frequency. Participation rate in laboratory testing after the intervention was compared to the year prior. Patient responses and feedback by text and survey were used to assess feasibility, acceptability and use of the intervention. Forty-two patients were recruited and 33 patients remained enrolled for the study duration. Recipients of the TM intervention demonstrated a significant improvement in participation rate in laboratory testing from 58% to 78% (Prate was also significantly higher than in non-intervention controls (P=.003). There was a high acceptability, response rate and a significant correlation with reported versus actual completion of laboratory tests by TM. TM reminders significantly improved participation in laboratory testing in AYA liver transplant patients. The intervention demonstrated feasibility, acceptability, and use with a high proportion of patients who engaged in and perceived a benefit from using this technology.

  12. Program of experiments for the operating phase of the Underground Research Laboratory

    International Nuclear Information System (INIS)

    Simmons, G.R.; Bilinsky, D.M.; Davison, C.C.; Gray, M.N.; Kjartanson, B.H.; Martin, C.D.; Peters, D.A.; Lang, P.A.

    1992-09-01

    The Underground Research Laboratory (URL) is one of the major research and development facilities that AECL Research has constructed in support of the Canadian Nuclear Fuel Waste Management Program. The URL is a unique geotechnical research facility constructed in previously undisturbed plutonic rock, which was well characterized before construction. The site evaluation and construction phases of the URL project have been completed and the operating phase is beginning. A program of operating phase experiments that address AECL's objectives for in situ testing has been selected. These experiments were subjected to an external peer review and a subsequent review by the URL Experiment Committee in 1989. The comments from the external peer review were incorporated into the experiment plans, and the revised experiments were accepted by the URL Experiment Committee. Summaries of both reviews are presented. The schedule for implementing the experiments and the quality assurance to be applied during implementation are also summarized. (Author) (9 refs., 11 figs.)

  13. Highlighting High Performance: National Renewable Energy Laboratory's Thermal Test Facility, Golden, Colorado. Office of Building Technology State and Community Programs (BTS) Brochure

    International Nuclear Information System (INIS)

    Burgert, S.

    2001-01-01

    The National Renewable Energy Laboratory's Thermal Test Facility in Golden, Colorado, was designed using a whole-building approach-looking at the way the building's systems worked together most efficiently. Researchers monitor the performance of the 11,000-square-foot building, which boasts an energy cost savings of 63% for heating, cooling, and lighting. The basic plan of the building can be adapted to many needs, including retail and warehouse space. The Thermal Test Facility contains office and laboratory space; research focuses on the development of energy-efficiency and renewable energy technologies that are cost-effective and environmentally friendly

  14. 40 CFR Appendix II to Part 1054 - Duty Cycles for Laboratory Testing

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Duty Cycles for Laboratory Testing II.... 1054, App. II Appendix II to Part 1054—Duty Cycles for Laboratory Testing (a) Test handheld engines with the following steady-state duty cycle: G3 mode No. Engine speed a Torque(percent) b Weighting...

  15. Proceedings of the 5. DOE review of laboratory programs for women

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    The Fifth DOE Review of Laboratory Programs for Women was held at Brookhaven National Laboratory, May 6--8, 1996, and was co-sponsored by Princeton Plasma Physics Laboratory. The 1996 Review was organized as a Professional Workshop, that is, there were Invited Talks, plus Oral and Poster Presentations from the participants. These sessions were organized around the Focus Topics selected for the Review. The Focus Topics were: school-lab programs, college programs, positive image of women, cultural audits, employee development, employee mentoring, networking, dependent care, and alternate work schedules. On Monday evening, Toni Joseph gave an informal talk to the participants. She stressed the importance of submitting the Action Items for the respective facilities, and assured them that they would be looked at by the Office of Energy Research. On Tuesday morning, the DOE Points-of-Contact (POC) presented an overview of the past Reviews to give some background on the present DOE Review, and discussed plans for the future. The Review concluded with Focus Sessions, one for each Focus Topic. Each of these sessions was charged with producing a report on the session topic. The Focus Group Reports are included in the Proceedings, along with abstracts to the invited talks, oral presentations and poster presentations.

  16. Laboratory and field studies related to the Hydrologic Resources Management Program. Progress report, October 1, 1993--September 30, 1994

    International Nuclear Information System (INIS)

    Thompson, J.L.

    1995-03-01

    This report describes the work done at Los Alamos in FY 1994 for the Hydrologic Resources Management Program, a multi-organization project funded by the US Department of Energy/Nevada Operations Office. The authors participated in cooperative collaborations with University of California (UC), Berkeley, the Yucca Mountain Project, the Underground Test Area Operable Unit, and other participating organizations within the Hydrologic Resources Management Program (HRMP). They provided operational support to the Nevada Test Site (NTS) organizations by testing a water-evaporation system, championing the use of high-sensitivity logging equipment during drillbacks, and participating in the planning and execution of drilling operations at two nuclear test sites. Los Alamos personnel cooperated in preparing a proposal to drill beside and under a nuclear test located in unsaturated media. The authors gave assistance in laboratory work related to colloid migration and actinide sorption. In conjunction with personnel from the Lawrence Livermore Laboratory, they collected water samples from 10 wells at the NTS that are known to contain radionuclides. Their analyses of these samples suggest that radionuclides may not be moving away from cavity zones at appreciable rates. Recent field sampling shows clearly the need to purge wells of materials introduced during drilling and illustrates the inconsistency between water samples taken by bailing and those taken by pumping. 36 refs

  17. Laboratory audit as part of the quality assessment of a primary HPV-screening program.

    Science.gov (United States)

    Hortlund, Maria; Sundström, Karin; Lamin, Helena; Hjerpe, Anders; Dillner, Joakim

    2016-02-01

    As primary HPV screening programs are rolled out, methods are needed for routine quality assurance of HPV laboratory analyzes. To explore the use of similar design for audit as currently used in cytology-based screening, to estimate the clinical sensitivity to identify women at risk for CIN 3 or worse (CIN3+). Population-based cohort study conducted within the cervical screening program in Stockholm, Sweden, in 2011-2012. All women with histopathologically confirmed CIN3+ in the following two years were identified by registry analysis. Primary HPV and cytology screening results were collected. For women who had not been HPV tested, biobanked cytology samples were HPV-tested. If the original HPV result had been negative, the sample and subsequent biopsies were analyzed with broad HPV typing (general primer PCR and Luminex). 154 women had a biobanked prediagnostic cytology sample taken up to 2 years before a histopathologically confirmed CIN3+. The high-risk HPV-positivity was 97% (148/154 women), whereas 143/154 (94%) women had had a cytological abnormality. Among the six HPV-negative samples, one sample was HPV 33 positive in repeat testing whereas the other five cases were HPV-negative also on repeat testing, but HPV-positive in the subsequent tumor tissue. A sensitivity of the HPV test that is higher than the sensitivity of cytology suggests adequate quality of the testing. Regular audits of clinical sensitivity, similar to those of cytology-based screening, should be used also in HPV-based screening programs, in order to continuously monitor the performance of the analyzes. Copyright © 2015 Elsevier B.V. All rights reserved.

  18. Semiconductor laser joint study program with Rome Laboratory

    Science.gov (United States)

    Schaff, William J.; Okeefe, Sean S.; Eastman, Lester F.

    1994-09-01

    A program to jointly study vertical-cavity surface emitting lasers (VCSEL) for high speed vertical optical interconnects (VOI) has been conducted under an ES&E between Rome Laboratory and Cornell University. Lasers were designed, grown, and fabricated at Cornell University. A VCSEL measurement laboratory has been designed, built, and utilized at Rome Laboratory. High quality VCSEL material was grown and characterized by fabricating conventional lateral cavity lasers that emitted at the design wavelength of 1.04 microns. The VCSEL's emit at 1.06 microns. Threshold currents of 16 mA at 4.8 volts were obtained for 30 microns diameter devices. Output powers of 5 mW were measured. This is 500 times higher power than from the light emitting diodes employed previously for vertical optical interconnects. A new form of compositional grading using a cosinusoidal function has been developed and is very successful for reducing diode series resistance for high speed interconnection applications. A flip-chip diamond package compatible with high speed operation of 16 VCSEL elements has been designed and characterized. A flip-chip device binding effort at Rome Laboratory was also designed and initiated. This report presents details of the one-year effort, including process recipes and results.

  19. Buried Transuranic Waste Studies Program at the Idaho National Engineering Laboratory: Annual technology assessment and progress report

    International Nuclear Information System (INIS)

    Low, J.O.; Allman, D.W.; Shaw, P.G.; Sill, C.W.

    1987-01-01

    In-situ grouting, an improved-confinement technology that could be applied to the Idaho National Engineering Laboratory (INEL) shallow-land-buried transuranic (TRU) waste, is being investigated by EG and G Idaho, Inc. In situ grouting has been demonstrated as the culmination of a two-year engineering feasibility test at the INEL. In situ stabilization and hydrologic isolation of a simulated buried TRU waste trench at an arid site were performed using an experimental dynamic compaction in situ grouting process developed by Rockwell Hanford Operations (RHO). A series of laboratory evaluations relative to the grout permeation characteristics of microfine particulate cements with INEL-type soil was performed prior to the grouting operations. In addition, an extensive pre-grouting hydrologic assessment of the test trench was performed to support the performance assessment analysis. Laboratory testing of various chemical materials yielded a suitable hydrologic tracer for use in the hydrologic monitoring phase of the experiment. Various plutonium transport laboratory evaluations were performed to assess the plutonium retention capabilities of a microfine grout/INEL-soil waste product similar to that expected to result if the grout is injected in situ into the INEL test trench. The test trench will be hydrologically assessed in FY 1987 to determine if the RHO grouting system attained the performance acceptance criteria of the experiment. The report includes a technology assessment of buried waste technologies developed by other DOE sites. Field demonstrations at ORNL and Hanford are reported under this technology assessment. Also included is information on activities related to buried waste management at the INEL. These include environmental surveillance of the Radioactive Waste Management Complex and the Subsurface Migration Studies Program

  20. The laboratory test utilization management toolbox.

    Science.gov (United States)

    Baird, Geoffrey

    2014-01-01

    Efficiently managing laboratory test utilization requires both ensuring adequate utilization of needed tests in some patients and discouraging superfluous tests in other patients. After the difficult clinical decision is made to define the patients that do and do not need a test, a wealth of interventions are available to the clinician and laboratorian to help guide appropriate utilization. These interventions are collectively referred to here as the utilization management toolbox. Experience has shown that some tools in the toolbox are weak and other are strong, and that tools are most effective when many are used simultaneously. While the outcomes of utilization management studies are not always as concrete as may be desired, what data is available in the literature indicate that strong utilization management interventions are safe and effective measures to improve patient health and reduce waste in an era of increasing financial pressure.

  1. DTU PMU Laboratory Development - Testing and Validation

    OpenAIRE

    Garcia-Valle, Rodrigo; Yang, Guang-Ya; Martin, Kenneth E.; Nielsen, Arne Hejde; Østergaard, Jacob

    2010-01-01

    This is a report of the results of phasor measurement unit (PMU) laboratory development and testing done at the Centre for Electric Technology (CET), Technical University of Denmark (DTU). Analysis of the PMU performance first required the development of tools to convert the DTU PMU data into IEEE standard, and the validation is done for the DTU-PMU via a validated commercial PMU. The commercial PMU has been tested from the authors' previous efforts, where the response can be expected to foll...

  2. DOE standard: The Department of Energy Laboratory Accreditation Program administration

    International Nuclear Information System (INIS)

    1998-12-01

    This technical standard describes the US Department of Energy Laboratory Accreditation Program (DOELAP), organizational responsibilities, and the accreditation process. DOELAP evaluates and accredits personnel dosimetry and radiobioassay programs used for worker monitoring and protection at DOE and DOE contractor sites and facilities as required in Title 10, Code of Federal Regulations, Part 835, Occupational Radiation Protection. The purpose of this technical standard is to establish procedures for administering DOELAP and acquiring accreditation

  3. Science Faculty Belief Systems in a Professional Development Program: Inquiry in College Laboratories

    Science.gov (United States)

    Hutchins, Kristen L.; Friedrichsen, Patricia J.

    2012-12-01

    The purpose of this study was to investigate how science faculty members' belief systems about inquiry-based teaching changed through their experience in a professional development program. The program was designed to support early career science faculty in learning about inquiry and incorporating an inquiry-based approach to teaching laboratories. Data sources for this qualitative study included three semi-structured interviews, observations during the program and during faculty members' implementation in their courses, and a researcher's journal. In the first phase of data analysis, we created profiles for each of the four participants. Next, we developed assertions, and tested for confirming and disconfirming evidence across the profiles. The assertions indicated that, through the professional development program, participants' knowledge and beliefs about inquiry-based teaching shifted, placing more value on student-directed learning and classroom inquiry. Participants who were internally motivated to participate and held incoming positive attitudes toward the mini-journal inquiry-based approach were more likely to incorporate the approach in their future practice. Students' responses played a critical role in participants' belief systems and their decision to continue using the inquiry-based format. The findings from this study have implications for professional development design.

  4. Laboratory directed research and development program FY 2003

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Todd

    2004-03-27

    The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. In FY03, Berkeley Lab was authorized by DOE to establish a funding ceiling for the LDRD program of $15.0 M, which equates to about 3.2% of Berkeley Lab's FY03 projected operating and capital equipment budgets. This funding level was provided to develop new scientific ideas and opportunities and allow the Berkeley Lab Director an opportunity to initiate new directions. Budget constraints limited available resources, however, so only $10.1 M was expended for operating and $0.6 M for capital equipment (2.4% of actual Berkeley Lab FY03 costs). In FY03, scientists submitted 168 proposals, requesting over $24.2 M in operating funding. Eighty-two projects were funded, with awards ranging from $45 K to $500 K. These projects are summarized in Table 1.

  5. Waste certification program plan for Oak Ridge National Laboratory. Revision 2

    International Nuclear Information System (INIS)

    1997-09-01

    This document defines the waste certification program (WCP) developed for implementation at Oak Ridge National Laboratory (ORNL). The document describes the program structure, logic, and methodology for certification of ORNL wastes. The purpose of the WCP is to provide assurance that wastes are properly characterized and that the Waste Acceptance Criteria (WAC) for receiving facilities are met. The program meets the waste certification requirements for mixed (both radioactive and hazardous) and hazardous ncluding polychlorinated biphenyls (PCB) waste. Program activities will be conducted according to ORNL Level 1 document requirements

  6. Model Testing - Bringing the Ocean into the Laboratory

    DEFF Research Database (Denmark)

    Aage, Christian

    2000-01-01

    Hydrodynamic model testing, the principle of bringing the ocean into the laboratory to study the behaviour of the ocean itself and the response of man-made structures in the ocean in reduced scale, has been known for centuries. Due to an insufficient understanding of the physics involved, however......, the early model tests often gave incomplete or directly misleading results.This keynote lecture deals with some of the possibilities and problems within the field of hydrodynamic and hydraulic model testing....

  7. Performance testing of UK personal dosimetry laboratories

    International Nuclear Information System (INIS)

    Marshall, T.O.

    1985-01-01

    The proposed Ionising Radiations Regulations will require all UK personal dosimetry laboratories that monitor classified personnel to be approved for personal dosimetry by the Health and Safety Executive. It is suggested that these approvals should be based on general and supplementary criteria published by the British Calibration Service (BCS) for laboratory approval for the provision of personal dosimetry services. These criteria specify certain qualitative requirements and also indicate the need for regular tests of performance to be carried out to ensure constancy of dosimetric standards. This report concerns the latter. The status of the BCS criteria is discussed and the need for additional documents to cover new techniques and some modifications to existing documents is indicated. A means is described by which the technical performance of laboratories, concerned with personal monitoring for external radiations, can be assessed, both initially and ongoing. The costs to establish the scheme and operate it are also estimated. (author)

  8. Light Water Reactor Sustainability Program: Evaluation of Localized Cable Test Methods for Nuclear Power Plant Cable Aging Management Programs

    Energy Technology Data Exchange (ETDEWEB)

    Glass, Samuel W. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Fifield, Leonard S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hartman, Trenton S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-05-30

    This Pacific Northwest National Laboratory (PNNL) milestone report describes progress to date on the investigation of nondestructive test (NDE) methods focusing particularly on local measurements that provide key indicators of cable aging and damage. The work includes a review of relevant literature as well as hands-on experimental verification of inspection capabilities. As NPPs consider applying for second, or subsequent, license renewal (SLR) to extend their operating period from 60 years to 80 years, it important to understand how the materials installed in plant systems and components will age during that time and develop aging management programs (AMPs) to assure continued safe operation under normal and design basis events (DBE). Normal component and system tests typically confirm the cables can perform their normal operational function. The focus of the cable test program is directed toward the more demanding challenge of assuring the cable function under accident or DBE. Most utilities already have a program associated with their first life extension from 40 to 60 years. Regrettably, there is neither a clear guideline nor a single NDE that can assure cable function and integrity for all cables. Thankfully, however, practical implementation of a broad range of tests allows utilities to develop a practical program that assures cable function to a high degree. The industry has adopted 50% elongation at break (EAB) relative to the un-aged cable condition as the acceptability standard. All tests are benchmarked against the cable EAB test. EAB is a destructive test so the test programs must apply an array of other NDE tests to assure or infer the overall set of cable’s system integrity. These cable NDE programs vary in rigor and methodology. As the industry gains experience with the efficacy of these programs, it is expected that implementation practice will converge to a more common approach. This report addresses the range of local NDE cable tests that are

  9. The value of assessments in Lawrence Livermore National Laboratory's Waste Certification Programs

    International Nuclear Information System (INIS)

    Ryan, E.M.

    1995-05-01

    This paper will discuss the value of assessments in Lawrence Livermore National Laboratory's Waste Certification Programs by: introducing the organization and purpose of the LLNL Waste Certification Programs for transuranic, low-level, and hazardous waste; examining the differences in internal assessment/audit requirements for these programs; discussing the values and costs of assessments in a waste certification program; presenting practical recommendations to maximize the value of your assessment programs; and presenting improvements in LLNL's waste certification processes that resulted from assessments

  10. TEST PROGRAM FOR ALUMINA REMOVAL AND SODIUM HYDROXIDE REGENERATION FROM HANFORD WASTE BY LITHIUM HYDROTALCITE PRECIPITATION

    Energy Technology Data Exchange (ETDEWEB)

    SAMS TL; GEINESSE D

    2011-01-28

    This test program sets a multi-phased development path to support the development of the Lithium Hydrotalcite process, in order to raise its Technology Readiness Level from 3 to 6, based on tasks ranging from laboratory scale scientific research to integrated pilot facilities.

  11. Test Program For Alumina Removal And Sodium Hydroxide Regeneration From Hanford Waste By Lithium Hydrotalcite Precipitation

    International Nuclear Information System (INIS)

    Sams, T.L.; Geinesse, D.

    2011-01-01

    This test program sets a multi-phased development path to support the development of the Lithium Hydrotalcite process, in order to raise its Technology Readiness Level from 3 to 6, based on tasks ranging from laboratory scale scientific research to integrated pilot facilities.

  12. Los Alamos National Laboratory Science Education Program. Annual progress report, October 1, 1995--September 30, 1996

    Energy Technology Data Exchange (ETDEWEB)

    Gill, D.H.

    1997-01-01

    The National Teacher Enhancement program (NTEP) is a three-year, multi-laboratory effort funded by the National Science Foundation and the Department of Energy to improve elementary school science programs. The Los Alamos National Laboratory targets teachers in northern New Mexico. FY96, the third year of the program, involved 11 teams of elementary school teachers (grades 4-6) in a three-week summer session, four two-day workshops during the school year and an on-going planning and implementation process. The teams included twenty-one teachers from 11 schools. Participants earned a possible six semester hours of graduate credit for the summer institute and two hours for the academic year workshops from the University of New Mexico. The Laboratory expertise in the earth and environmental science provided the tie between the Laboratory initiatives and program content, and allowed for the design of real world problems.

  13. Biomedical and environmental sciences programs at the Oak Ridge National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Richmond, C.R.; Johnson, C.A.

    1988-02-01

    This progress report summarizes the research and development activities conducted in the Biomedical and Environmental Sciences Programs of Oak Ridge National Laboratory. The report is structured to provide descriptions of current activities and accomplishments in each of the major organizational units. Following the accounts of research programs, is a list of publications and awards to its members. 6 figs., 14 tabs.

  14. Biomedical and environmental sciences programs at the Oak Ridge National Laboratory

    International Nuclear Information System (INIS)

    Richmond, C.R.; Johnson, C.A.

    1988-02-01

    This progress report summarizes the research and development activities conducted in the Biomedical and Environmental Sciences Programs of Oak Ridge National Laboratory. The report is structured to provide descriptions of current activities and accomplishments in each of the major organizational units. Following the accounts of research programs, is a list of publications and awards to its members. 6 figs., 14 tabs

  15. Wind Structural Testing Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This facility provides office space for industry researchers, experimental laboratories, computer facilities for analytical work, and space for assembling components...

  16. Laboratory Directed Research and Development Program FY2011

    Energy Technology Data Exchange (ETDEWEB)

    none, none

    2012-04-27

    Berkeley Lab's research and the Laboratory Directed Research and Development (LDRD) program support DOE's Strategic Themes that are codified in DOE's 2006 Strategic Plan (DOE/CF-0010), with a primary focus on Scientific Discovery and Innovation. For that strategic theme, the Fiscal Year (FY) 2011 LDRD projects support each one of the three goals through multiple strategies described in the plan. In addition, LDRD efforts support the four goals of Energy Security, the two goals of Environmental Responsibility, and Nuclear Security (unclassified fundamental research that supports stockpile safety and nonproliferation programs). Going forward in FY 2012, the LDRD program also supports the Goals codified in the new DOE Strategic Plan of May, 2011. The LDRD program also supports Office of Science strategic plans, including the 20-year Scientific Facilities Plan and the Office of Science Strategic Plan. The research also supports the strategic directions periodically under consideration and review by the Office of Science Program Offices, such as LDRD projects germane to new research facility concepts and new fundamental science directions. Brief summares of projects and accomplishments for the period for each division are included.

  17. Supplemental investigations in support of environmental assessments by the Idaho INEL Oversight Program at the Idaho National Engineering Laboratory

    International Nuclear Information System (INIS)

    1992-01-01

    This document reports on the status of supplemental investigations in support of environmental assessments by the Idaho INEL Oversight Program at the Idaho National Engineering Laboratory. Included is information on hydrology studies in wells open through large intervals, unsaturated zone contamination and transport processes, surface water-groundwater interactions, regional groundwater flow, and independent testing of air quality data

  18. Quality of HIV laboratory testing in Tanzania: a situation analysis ...

    African Journals Online (AJOL)

    December 2004 to February 2005 in 12 laboratories which were conveniently selected to represent all the zones of Tanzania. The questionnaires comprised of questions on laboratory particulars, internal and external quality control for HIV testing and quality control of reagents. Source and level of customer satisfaction of ...

  19. Sand characterization by combined centrifuge and laboratory tests

    OpenAIRE

    GAUDIN, C; SCHNAID, F; GARNIER, J

    2005-01-01

    The purpose of this paper is to evaluate new methods of interpretation of in situ tests in sand from correlations established from centrifuge and laboratory data. Emphasis is given to methods that are based on the combination of measurements from independent tests, such as the ratio of the elastic stiffness to ultimate strenght and the ratio of cone resistance and limit pressure. For that purpose, a series of centrifuge tests using a cone penetrometer and a cone pressuremeter was carried out ...

  20. Competency assessment of microbiology medical laboratory technologists in Ontario, Canada.

    Science.gov (United States)

    Desjardins, Marc; Fleming, Christine Ann

    2014-08-01

    Accreditation in Ontario, Canada, requires that licensed clinical laboratories participate in external quality assessment (also known as proficiency testing) and perform competency evaluation of their staff. To assess the extent of ongoing competency assessment practices, the Quality Management Program--Laboratory Services (QMP-LS) Microbiology Committee surveyed all 112 licensed Ontario microbiology laboratories. The questionnaire consisted of a total of 21 questions that included yes/no, multiple-choice, and short-answer formats. Participants were asked to provide information about existing programs, the frequency of testing, what areas are evaluated, and how results are communicated to the staff. Of the 111 responding laboratories, 6 indicated they did not have a formal evaluation program since they perform only limited bacteriology testing. Of the remaining 105 respondents, 87% perform evaluations at least annually or every 2 years, and 61% include any test or task performed, whereas 16% and 10% focus only on problem areas and high-volume complex tasks, respectively. The most common methods of evaluation were review of external quality assessment (EQA) challenges, direct observation, and worksheet review. With the exception of one participant, all communicate results to staff, and most take remedial action to correct the deficiencies. Although most accredited laboratories have a program to assess the ongoing competency of their staff, the methods used are not standardized or consistently applied, indicating that there is room for improvement. The survey successfully highlighted potential areas for improvement and allowed the QMP-LS Microbiology Committee to provide guidance to Ontario laboratories for establishing or improving existing microbiology-specific competency assessment programs. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

  1. Engineering testing and technology projects FY 1996 Site Support Program Plan, WBS 6.3.3 and 6.3.8. Revision 1

    International Nuclear Information System (INIS)

    Brown, L.C.

    1995-10-01

    The engineering laboratory services for development, assembly, testing, and evaluation to support the resolution of WHC, Hanford, and DOE complex wide engineering issues for 1996 are presented. Primary customers are: TWRS, spent nuclear fuels, transition projects, liquid effluent program, and other Hanford contractors and programs. Products and services provided include: fabrication and assembly facilities for prototype and test equipment, development testing, proof of principle testing, instrumentation testing, nondestructive examination application development and testing, prototype equipment design and assembly, chemical engineering unit operations testing, engineering test system disposal, and safety issue resolution

  2. Glovebox glove change program at Technical Area 55, Los Alamos National Laboratory

    International Nuclear Information System (INIS)

    Olivas, J.D.; Burkett, B.O.; Weier, D.R.

    1992-01-01

    A formal glovebox glove change program is planned for the the gloveboxes in technical area 55 at the Los Alamos National laboratory. The program will increase worker safety by reducing the chance of having worn out gloves in service. The Los Alamos program is based on a similar successful program at the Rocky Flats Plant in Golden, Colorado. Glove change frequencies at Rocky Flats were determined statistically, and are based on environmental factors the glovebox gloves are subjected to

  3. Antifungal susceptibility testing method for resource constrained laboratories

    Directory of Open Access Journals (Sweden)

    Khan S

    2006-01-01

    Full Text Available Purpose: In resource-constrained laboratories of developing countries determination of antifungal susceptibility testing by NCCLS/CLSI method is not always feasible. We describe herein a simple yet comparable method for antifungal susceptibility testing. Methods: Reference MICs of 72 fungal isolates including two quality control strains were determined by NCCLS/CLSI methods against fluconazole, itraconazole, voriconazole, amphotericin B and cancidas. Dermatophytes were also tested against terbinafine. Subsequently, on selection of optimum conditions, MIC was determined for all the fungal isolates by semisolid antifungal agar susceptibility method in Brain heart infusion broth supplemented with 0.5% agar (BHIA without oil overlay and results were compared with those obtained by reference NCCLS/CLSI methods. Results: Comparable results were obtained by NCCLS/CLSI and semisolid agar susceptibility (SAAS methods against quality control strains. MICs for 72 isolates did not differ by more than one dilution for all drugs by SAAS. Conclusions: SAAS using BHIA without oil overlay provides a simple and reproducible method for obtaining MICs against yeast, filamentous fungi and dermatophytes in resource-constrained laboratories.

  4. Laboratory Tests in the Development of WaveCat

    Directory of Open Access Journals (Sweden)

    James Allen

    2016-12-01

    Full Text Available WaveCat, a novel overtopping Wave Energy Converter, was tested with the aim of determining its performance under different sea states, establishing a starting point for optimisation of the device, numerical model validation and proof-of-concept for the control systems. The tests were carried out at a 1:30 scale in the Ocean Basin of the COAST Laboratory at University of Plymouth. A state-of-the-art control system was implemented, and overtopping rates and device motions were recorded alongside the wave field. It was observed that power generation is dependent on both the wave height and period, with smaller periods tending to produce greater overtopping rates, and therefore greater power generation, for the same wave height. Due to time constraints in the laboratory, only one configuration of draft/freeboard was tested; with this configuration, overtopping occurred under significant wave heights of 0.083 m or more, corresponding to 2.5 m or more in prototype values. These experimental results form the basis for future development and optimisation of WaveCat.

  5. Software for illustrative presentation of basic clinical characteristics of laboratory tests--GraphROC for Windows.

    Science.gov (United States)

    Kairisto, V; Poola, A

    1995-01-01

    GraphROC for Windows is a program for clinical test evaluation. It was designed for the handling of large datasets obtained from clinical laboratory databases. In the user interface, graphical and numerical presentations are combined. For simplicity, numerical data is not shown unless requested. Relevant numbers can be "picked up" from the graph by simple mouse operations. Reference distributions can be displayed by using automatically optimized bin widths. Any percentile of the distribution with corresponding confidence limits can be chosen for display. In sensitivity-specificity analysis, both illness- and health-related distributions are shown in the same graph. The following data for any cutoff limit can be shown in a separate click window: clinical sensitivity and specificity with corresponding confidence limits, positive and negative likelihood ratios, positive and negative predictive values and efficiency. Predictive values and clinical efficiency of the cutoff limit can be updated for any prior probability of disease. Receiver Operating Characteristics (ROC) curves can be generated and combined into the same graph for comparison of several different tests. The area under the curve with corresponding confidence interval is calculated for each ROC curve. Numerical results of analyses and graphs can be printed or exported to other Microsoft Windows programs. GraphROC for Windows also employs a new method, developed by us, for the indirect estimation of health-related limits and change limits from mixed distributions of clinical laboratory data.

  6. Results of Laboratory Testing of Advanced Power Strips

    Energy Technology Data Exchange (ETDEWEB)

    Earle, L. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Sparn, B. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2012-08-01

    Presented at the ACEEE Summer Study on Energy Efficiency in Buildings on August 12-17, 2012, this presentation reports on laboratory tests of 20 currently available advanced power strip products, which reduce wasteful electricity use of miscellaneous electric loads in buildings.

  7. Astrophysical research at Lawrence Livermore Laboratory, proposal for a formal program

    Energy Technology Data Exchange (ETDEWEB)

    Lokke, W.A.; Tarter, C.B.

    1979-12-01

    Basic research is often characterized as self-directed, moving on its own timescale, spurred by the unexpected. An effective, organized basic astrophysics research program does not have to be a contradiction in terms. A broadly chartered, long-range LLL Astrophysics Research Program, created and recognized by LLL management, can benefit the general scientific community, stimulate the staff, maintain important capability, and enrich the Laboratory.

  8. Astrophysical research at Lawrence Livermore Laboratory, proposal for a formal program

    International Nuclear Information System (INIS)

    Lokke, W.A.; Tarter, C.B.

    1979-12-01

    Basic research is often characterized as self-directed, moving on its own timescale, spurred by the unexpected. An effective, organized basic astrophysics research program does not have to be a contradiction in terms. A broadly chartered, long-range LLL Astrophysics Research Program, created and recognized by LLL management, can benefit the general scientific community, stimulate the staff, maintain important capability, and enrich the Laboratory

  9. An overview of the Nuclear Electric Propulsion Space Test Program (NEPSTP) satellite

    International Nuclear Information System (INIS)

    Voss, S.S.; Reynolds, E.L.

    1994-01-01

    Early in 1992 the idea of purchasing a Russian designed and fabricated space reactor power system and integrating it with a US designed satellite went from fiction to reality with the purchase of the first two Topaz II reactors by the Strategic Defense Initiative Organization (now the Ballistic Missile Defense Organization (BMDO)). The New Mexico Alliance was formed to establish a ground test facility in which to perform nonnuclear systems testing of the Topaz II, and to evaluate the Topaz II system for flight testing with respect to safety, performance, and operability. In conjunction, SDIO requested that the Applied Physics Laboratory in Laurel, MD propose a mission and design a satellite in which the Topaz II could be used as the power source. The outcome of these two activities was the design of the Nuclear Electric Propulsion Space Test Program (NEPSTP) satellite which combines a modified Russian Topaz II power system with a US designed satellite to achieve a specified mission. Due to funding reduction within the SDIO, the Topaz II flight program was postponed indefinitely at the end of Fiscal year 1993. The purpose of this paper is to present an overview of the NEPSTP mission and the satellite design at the time the flight program ended

  10. Field and laboratory test methods for geomembranes during waste management facility construction

    International Nuclear Information System (INIS)

    Allen, S.R.; McCutchan, J.B.

    1991-01-01

    Hazardous waste management facilities are required to use approved lining and leak detection systems to prevent the migration of waste into the environment. Synthetic flexible membrane liners (FMLs) have effectively served as the critical barrier for waste containment and fluid migration. The U.S. EPA has established minimum technology requirements for the construction of lined facilities that include detailed and documented Construction Quality Assurance (CQA) plans. The U.S. EPA (EPA) recognizes that CQA during field construction is imperative for successful completion of project work and long-term facility operation. This paper discusses the importance of CQA during FML installation and the practical aspects of implementing a successful CQA program. Standard methods used for FML evaluation, in both the field and laboratory, are discussed and specific aspects of seam testing and data evaluation are addressed. The general importance of comprehensive definition of geomembrane seam field failures is strongly emphasized so that an appropriate response to test failures can be recommended

  11. 7 CFR 94.5 - Charges for laboratory service.

    Science.gov (United States)

    2010-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) COMMODITY LABORATORY TESTING PROGRAMS... costs for analysis of mandatory egg product samples at Science and Technology Division laboratories...

  12. Formal training program for nuclear material custodians at Hanford Engineering Development Laboratory

    International Nuclear Information System (INIS)

    Scott, D.D.

    1979-01-01

    Hanford Engineering Development Laboratory (HEDL) has established a formal training program for nuclear material (NM) custodians. The program, designed to familiarize the custodian with the fundamental concepts of proper nuclear materials control and accountability, is conducted on a semiannual basis. The program is prepared and presented by the Safeguards and Materials Management Section of HEDL and covers 14 subjects on accountability, documentation, transportation, custodian responsibilities, and the safeguarding of nuclear material

  13. Electronic laboratory quality assurance program: A method of enhancing the prosthodontic curriculum and addressing accreditation standards.

    Science.gov (United States)

    Moghadam, Marjan; Jahangiri, Leila

    2015-08-01

    An electronic quality assurance (eQA) program was developed to replace a paper-based system and to address standards introduced by the Commission on Dental Accreditation (CODA) and to improve educational outcomes. This eQA program provides feedback to predoctoral dental students on prosthodontic laboratory steps at New York University College of Dentistry. The purpose of this study was to compare the eQA program of performing laboratory quality assurance with the former paper-based format. Fourth-year predoctoral dental students (n=334) who experienced both the paper-based and the electronic version of the quality assurance program were surveyed about their experiences. Additionally, data extracted from the eQA program were analyzed to identify areas of weakness in the curriculum. The study findings revealed that 73.8% of the students preferred the eQA program to the paper-based version. The average number of treatments that did not pass quality assurance standards was 119.5 per month. This indicated a 6.34% laboratory failure rate. Further analysis of these data revealed that 62.1% of the errors were related to fixed prosthodontic treatment, 27.9% to partial removable dental prostheses, and 10% to complete removable dental prostheses in the first 18 months of program implementation. The eQA program was favored by dental students who have experienced both electronic and paper-based versions of the system. Error type analysis can yield the ability to create customized faculty standardization sessions and refine the didactic and clinical teaching of the predoctoral students. This program was also able to link patient care activity with the student's laboratory activities, thus addressing the latest requirements of the CODA regarding the competence of graduates in evaluating laboratory work related to their patient care. Copyright © 2015 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  14. Oak Ridge National Laboratory Transuranic Waste Certification Program

    International Nuclear Information System (INIS)

    Smith, J.H.; Bates, L.D.; Box, W.D.; Aaron, W.S.; Setaro, J.A.

    1988-08-01

    The US Department of Energy (DOE) has requested that all DOE facilities handling defense transuranic (TRU) waste develop and implement a program whereby all TRU waste will be contained, stored, and shipped to the Waste Isolation Pilot Plant (WIPP) in accordance with the requirements set forth in the DOE certification documents WIPP-DOE-069, 114, 120, 137, 157, and 158. The program described in this report describes how Oak Ridge National Laboratory (ORNL) intends to comply with these requirements and the techniques and procedures used to ensure that ORNL TRU wastes are certifiable for shipment to WIPP. This document describes the program for certification of newly generated (NG) contact-handled transuranic (CH-TRU) waste. Previsions have been made for addenda, which will extend the coverage of this document to include certification of stored CH-TRU and NG and stored remote-handled transuranic (RH-TRU) waste, as necessary. 24 refs., 11 figs., 4 tabs

  15. Interlaboratory test comparison among Environmental Radioactivity Laboratories using the ISO/IUPAC/AOAC Protocol

    International Nuclear Information System (INIS)

    Romero, L.; Ramos, L.; Salas, R.

    1998-01-01

    World-wide acceptance of results from radiochemical analyses requires reliable, traceable and comparable measurements to SI units, particularly when data sets generated by laboratories are to contribute to evaluation of data from environmental pollution research and monitoring programmes. The Spanish Nuclear Safety Council (CSN) organizes in collaboration with CIEMAT periodical interlaboratory test comparisons for environmental radioactivity laboratories aiming to provide them with the necessary means to asses the quality of their results. This paper presents data from the most recent exercise which, for the first time, was evaluated following the procedure recommended in the ISO/IUPAC/AOAC Harmonized Protocol for the proficiency testing of analytical laboratories (1). The test sample was a Reference Material provided by the IAEA-AQCS, a lake sediment containing the following radionuclides: k-40, Ra-226, Ac-228, Cs-137, Sr-90, Pu-(239+240). The results of the proficiency test were computed for the 28 participating laboratories using the z-score approach, the evaluation of the exercises is presented in the paper. The use of a z-score classification has demonstrated to provide laboratories with a more objective means of assessing and demonstrating the reliability of the data they are producing. Analytical proficiency of the participating laboratories has been found to be satisfactory in 57 to 100 percent of cases. (1)- The International harmonized protocol for the proficiency testing of (chemical) analytical laboratories. Pure and Appl. Chem. Vol. 65, n 9, pp. 2123-2144, 1993 IUPAC. GB (Author) 3 refs

  16. The marine corrosion program developed by Nuclebras

    International Nuclear Information System (INIS)

    Moreira, P.A.P.; Quinan, M.A.

    1986-01-01

    A marine corrosion program is being developed by NUCLEBRAS and NUCLEN. This program consists in carrying out non-accelerated experiments in marine atmosphere, with immersion in sewater and laboratory accelerated tests. The purpose is to obtain a correlation between the corrosion rates observed in non-accelerated conditions and laboratory tests. Through these results it is inteded, only with laboratory tests, to estimate the bahavior of similar materials when tsted in similar marine atmosphereic conditions. Some aspects observed in the implementation of the program and some results so far obtained are discussed. (Author) [pt

  17. Safety in the Chemical Laboratory: Tested Disposal Methods for Chemical Wastes from Academic Laboratories.

    Science.gov (United States)

    Armour, M. A.; And Others

    1985-01-01

    Describes procedures for disposing of dichromate cleaning solution, picric acid, organic azides, oxalic acid, chemical spills, and hydroperoxides in ethers and alkenes. These methods have been tested under laboratory conditions and are specific for individual chemicals rather than for groups of chemicals. (JN)

  18. National survey on intra-laboratory turnaround time for some most common routine and stat laboratory analyses in 479 laboratories in China.

    Science.gov (United States)

    Fei, Yang; Zeng, Rong; Wang, Wei; He, Falin; Zhong, Kun; Wang, Zhiguo

    2015-01-01

    To investigate the state of the art of intra-laboratory turnaround time (intra-TAT), provide suggestions and find out whether laboratories accredited by International Organization for Standardization (ISO) 15189 or College of American Pathologists (CAP) will show better performance on intra-TAT than non-accredited ones. 479 Chinese clinical laboratories participating in the external quality assessment programs of chemistry, blood gas, and haematology tests organized by the National Centre for Clinical Laboratories in China were included in our study. General information and the median of intra-TAT of routine and stat tests in last one week were asked in the questionnaires. The response rate of clinical biochemistry, blood gas, and haematology testing were 36% (479/1307), 38% (228/598), and 36% (449/1250), respectively. More than 50% of laboratories indicated that they had set up intra-TAT median goals and almost 60% of laboratories declared they had monitored intra-TAT generally for every analyte they performed. Among all analytes we investigated, the intra-TAT of haematology analytes was shorter than biochemistry while the intra-TAT of blood gas analytes was the shortest. There were significant differences between median intra-TAT on different days of the week for routine tests. However, there were no significant differences in median intra-TAT reported by accredited laboratories and non-accredited laboratories. Many laboratories in China are aware of intra-TAT control and are making effort to reach the target. There is still space for improvement. Accredited laboratories have better status on intra-TAT monitoring and target setting than the non-accredited, but there are no significant differences in median intra-TAT reported by them.

  19. Modernization of laboratories of test of electric measurer

    International Nuclear Information System (INIS)

    Cuervo, Luis Felipe

    1999-01-01

    The paper presents to the companies that possess test laboratories and calibration of electric measurer, an economic alternative for their modernization, using the repontentiation like an economic solution that it liberates resources to be used in other areas that they want it

  20. SALE: Safeguards Analytical Laboratory Evaluation computer code

    International Nuclear Information System (INIS)

    Carroll, D.J.; Bush, W.J.; Dolan, C.A.

    1976-09-01

    The Safeguards Analytical Laboratory Evaluation (SALE) program implements an industry-wide quality control and evaluation system aimed at identifying and reducing analytical chemical measurement errors. Samples of well-characterized materials are distributed to laboratory participants at periodic intervals for determination of uranium or plutonium concentration and isotopic distributions. The results of these determinations are statistically-evaluated, and each participant is informed of the accuracy and precision of his results in a timely manner. The SALE computer code which produces the report is designed to facilitate rapid transmission of this information in order that meaningful quality control will be provided. Various statistical techniques comprise the output of the SALE computer code. Assuming an unbalanced nested design, an analysis of variance is performed in subroutine NEST resulting in a test of significance for time and analyst effects. A trend test is performed in subroutine TREND. Microfilm plots are obtained from subroutine CUMPLT. Within-laboratory standard deviations are calculated in the main program or subroutine VAREST, and between-laboratory standard deviations are calculated in SBLV. Other statistical tests are also performed. Up to 1,500 pieces of data for each nuclear material sampled by 75 (or fewer) laboratories may be analyzed with this code. The input deck necessary to run the program is shown, and input parameters are discussed in detail. Printed output and microfilm plot output are described. Output from a typical SALE run is included as a sample problem

  1. Avoidance test with Eisenia fetida as indicator for the habitat function of soils. Results of a laboratory comparison test

    Energy Technology Data Exchange (ETDEWEB)

    Hund-Rinke, K. [Fraunhofer Inst. for Molecular Biology and Applied Ecology, Schmallenberg (Germany); Achazi, R.; Warnecke, D. [Free Univ. of Berlin, Inst. for Biology, Berlin (Germany); Roembke, J. [ECT Oekotoxikologie GmbH, Floersheim (Germany)

    2003-07-01

    Intention, Goal, Scope, Background. The habitat function of soils is often assessed using the reproduction test with Eisenia fetida. As this test is rather labour-intensive, an alternative is needed which is less cost-intensive in terms of duration and workload, but gives reasonable results. The avoidance test with E. fetida is a suitable screening test meeting these criteria. However, before a novel test system can be generally recommended it has to be ensured that comparable results are acquired from different laboratories on the basis of the respective test guideline. Objective. The avoidance test with E. fetida was performed as laboratory comparison test. The results were compared with those of the earthworm acute and reproduction tests carried out with the same soils. Methods. The three tests were performed by three laboratories using eight contaminated soils and three control soils. The contaminated soils were mixed with the control soils to obtain different concentrations of the contamination. (orig.)

  2. Fermi National Accelerator Laboratory Annual Program Review 2000

    Energy Technology Data Exchange (ETDEWEB)

    2000-03-01

    This book is submitted as one written part of the 2000 Annual DOE High Energy Physics Program Review of Fermilab, scheduled March 22-24, 2000. In it are Director's Overview, some experimental highlights, discussions of several projects, and descriptions of the functions and activities of the four laboratory divisions. This book should be read in conjunction with the 2000 Fermilab Workbook and the review presentations (both in formal sessions and at the poster session).

  3. Participation of the IPEN/CNEN/SP Environmental Diagnostic Division on programs of laboratory intercomparisons in environmental samples

    International Nuclear Information System (INIS)

    Cotrim, Marycel Barboza; Sato, Ivone Mulako; Salvador, Vera Lucia R.; Dantas, Elizabeth Sonoda Keiko; Cantagallo, Maria Ines; Lemes, Marcos Jose L.; Scapin, Marcos Antonio; Sisti, Cristina; Silveira, Elias Santana; Furusawa, Helio Akira; Pires, Maria Aparecida Faustino

    2003-01-01

    The present work presents the participation of the Environmental Diagnostic Division Laboratories (MQA) at the intercomparison national and international laboratories, (PI/SABESP - Interlaboratory Sao Paulo, Brazil, Program; Program for Interlaboratorial Analytic Quality Control of Metals in Water (CBM/COMETRO); Programa para La Calidad de las Mediciones Quimicas (PCQM/INTI) - Argentine, and the Commission d'Etablissement des Methodes d'Analyse, France (CETAMA/CEA). Those essay providers have using statistical tests such as the t-Student, Zscore and Cochran and Grubbs for the data evaluations. The obtained results are presented involving the analytical such as atomic absorption spectrometry: flame, graphite oven and hydride generation (AAS), emission spectrometry with induced plasma (ICP-OES), X-ray fluorescence WD-XRFS), ion chromatography and voltametry (VRA). The elements such as B, Al, K, Mg, Ca, Cr, Fe, Co, Cu, Zn and Pb, and the anions such as Cl-, NO 3 - , SO 4 2- and F - , were determined at trace level (mgL -1 ), and the elements such as Cr, As, Cd, Pb e Hg, at the trace level (μgL -1 ) in water matrices. The evaluation of analytical results, in the period 1997 to 2002, demonstrate a continuous improvement evidencing the importance of Laboratories participation at those type of exercises

  4. 42 CFR 493.1415 - Condition: Laboratories performing moderate complexity testing; clinical consultant.

    Science.gov (United States)

    2010-10-01

    ... § 493.1415 Condition: Laboratories performing moderate complexity testing; clinical consultant. The laboratory must have a clinical consultant who meets the qualification requirements of § 493.1417 of this... 42 Public Health 5 2010-10-01 2010-10-01 false Condition: Laboratories performing moderate...

  5. Oak Ridge National Laboratory Radiation Control Program - Partners in Site Restoration

    International Nuclear Information System (INIS)

    Jones, S. L.; Stafford, M. W.

    2002-01-01

    In 1998, the U.S. Department of Energy (DOE) awarded the Management and Integration (M and I) contract for all five of the Oak Ridge Operations (ORO) facilities to Bechtel Jacobs Company LLC (BJC). At Oak Ridge National Laboratory (ORNL), a world renowned national laboratory and research and development facility, the BJC mission involves executing the DOE Environmental Management (EM) program. In addition to BJC's M and I contract, UT-Battelle, LLC, a not-for-profit company, is the Management and Operating (M and O) contractor for DOE on the ORNL site. As part of ORNL's EM program, legacy inactive facilities (i.e., reactors, nuclear material research facilities, burial grounds, and underground storage tanks) are transferred to BJC and are designated as remediation, decontamination and decommissioning (D and D), or long-term surveillance and maintenance (S and M) facilities. Facilities operated by both UT-Battelle and BJC are interspersed throughout the site and are usually in close proximity. Both UT-Battelle and BJC have DOE-approved Radiation Protection Programs established in accordance with 10 CFR 835. The BJC Radiological Control (RADCON) Program adapts to the M and I framework and is comprised of a combination of subcontracted program responsibilities with BJC oversight. This paper focuses on the successes and challenges of executing the BJC RADCON Program for BJC's ORNL Project through a joint M and I contractor relationship, while maintaining a positive working relationship and partnership with UT-Battelle's Radiation Protection organization

  6. An overview of experimental results obtained under the prestressed concrete nuclear pressure vessel development program at the Oak Ridge National Laboratory

    International Nuclear Information System (INIS)

    Naus, D.J.

    1979-01-01

    Under the Prestressed Concrete Nuclear Pressure Development Program at the Oak Ridge National Laboratory, various aspects of Prestressed Concrete Pressure Vessels (PCPVs) are investigated with respect to reliability, structural performance, constructability, and economy. These investigations are conducted under the High-Temperature Gas-Cooled Reactor (HTGR) Program and the Gas-Cooled Fast Reactor (GCFR) Program. The objectives are to: (1) provide technical support to ongoing PCPV design activities, (2) contribute to the overall technological data base, and (3) provide independent review and evaluations. Specific areas of interest at present include finite-element analysis development, materials and structural behaviour tests, instrumentation evaluations and development, and structural model tests. The following provides an overview of both the HTGR and GCFR PCPV activities and a summary of recent experimental results

  7. Waste certification program plan for Oak Ridge National Laboratory. Revision 1

    International Nuclear Information System (INIS)

    Orrin, R.C.

    1997-05-01

    This document defines the waste certification program developed for implementation at Oak Ridge National Laboratory (ORNL). The document describes the program structure, logic, and methodology for certification of ORNL wastes. The purpose of the waste certification program is to provide assurance that wastes are properly characterized and that the Waste Acceptance Criteria (WAC) for receiving facilities are met. The program meets the waste certification requirements outlined in US Department of Energy (DOE) Order 5820.2A, Radioactive Waste Management, and ensures that 40 CFR documentation requirements for waste characterization are met for mixed (both radioactive and hazardous) and hazardous (including polychlorinated biphenyls) waste. Program activities will be conducted according to ORNL Level 1 document requirements

  8. Laboratory Diagnosis and Susceptibility Testing for Mycobacterium tuberculosis.

    Science.gov (United States)

    Procop, Gary W

    2016-12-01

    The laboratory, which utilizes some of the most sophisticated and rapidly changing technologies, plays a critical role in the diagnosis of tuberculosis. Some of these tools are being employed in resource-challenged countries for the rapid detection and characterization of Mycobacterium tuberculosis. Foremost, the laboratory defines appropriate specimen criteria for optimal test performance. The direct detection of mycobacteria in the clinical specimen, predominantly done by acid-fast staining, may eventually be replaced by rapid-cycle PCR. The widespread use of the Xpert MTB/RIF (Cepheid) assay, which detects both M. tuberculosis and key genetic determinants of rifampin resistance, is important for the early detection of multidrug-resistant strains. Culture, using both broth and solid media, remains the standard for establishing the laboratory-based diagnosis of tuberculosis. Cultured isolates are identified far less commonly by traditional biochemical profiling and more commonly by molecular methods, such as DNA probes and broad-range PCR with DNA sequencing. Non-nucleic acid-based methods of identification, such as high-performance liquid chromatography and, more recently, matrix-assisted laser desorption/ionization-time of flight mass spectrometry, may also be used for identification. Cultured isolates of M. tuberculosis should be submitted for susceptibility testing according to standard guidelines. The use of broth-based susceptibility testing is recommended to significantly decrease the time to result. Cultured isolates may also be submitted for strain typing for epidemiologic purposes. The use of massive parallel sequencing, also known as next-generation sequencing, promises to continue to this molecular revolution in mycobacteriology, as whole-genome sequencing provides identification, susceptibility, and typing information simultaneously.

  9. Utility of repeat testing of critical values: a Q-probes analysis of 86 clinical laboratories.

    Science.gov (United States)

    Lehman, Christopher M; Howanitz, Peter J; Souers, Rhona; Karcher, Donald S

    2014-06-01

    A common laboratory practice is to repeat critical values before reporting the test results to the clinical care provider. This may be an unnecessary step that delays the reporting of critical test results without adding value to the accuracy of the test result. To determine the proportions of repeated chemistry and hematology critical values that differ significantly from the original value as defined by the participating laboratory, to determine the threshold differences defined by the laboratory as clinically significant, and to determine the additional time required to analyze the repeat test. Participants prospectively reviewed critical test results for 4 laboratory tests: glucose, potassium, white blood cell count, and platelet count. Participants reported the following information: initial and repeated test result; time initial and repeat results were first known to laboratory staff; critical result notification time; if the repeat result was still a critical result; if the repeat result was significantly different from the initial result, as judged by the laboratory professional or policy; significant difference threshold, as defined by the laboratory; the make and model of the instrument used for primary and repeat testing. Routine, repeat analysis of critical values is a common practice. Most laboratories did not formally define a significant difference between repeat results. Repeated results were rarely considered significantly different. Median repeated times were at least 17 to 21 minutes for 10% of laboratories. Twenty percent of laboratories reported at least 1 incident in the last calendar year of delayed result reporting that clinicians indicated had adversely affected patient care. Routine repeat analysis of automated chemistry and hematology critical values is unlikely to be clinically useful and may adversely affect patient care.

  10. Qualification of testing laboratories of Comision Nacional de Energia Atomica - CNEA

    International Nuclear Information System (INIS)

    Casa, Adriana; Palacios, Tulio; Peretti, Matilde; Pucci, Gladys; Resnizki, Sara

    1996-01-01

    Testing and calibration laboratories of the Argentine Atomic Energy Commission which made services for the nuclear and conventional industries must prove the reliability of their results. It is achieved implanting at the laboratories, a management quality system, to proof the capacity and technical aptitude, with the establish minimal requirements. When the requirement are fulfilled, the laboratory would be in conditions for a national level accreditation within the National System of Standards, Quality and Certification, recently created for our national government. The Laboratories Calibration Board of CNEA had made some assessments of a group of laboratories in order to determine their quality level. (author)

  11. Summary of research for the Inertial Confinement Fusion Program at Los Alamos National Laboratory

    International Nuclear Information System (INIS)

    Cartwright, D.C.

    1985-03-01

    The information presented in this report is a summary of the status of the Inertial Confinement Fusion (ICF) program at the Los Alamos National Laboratory as of February 1985. This report contains material on the existing high-power CO 2 laser driver (Antares), the program to determine the potential of KrF as an ICF driver, heavy-ion accelerators as drivers for ICF, target fabrication for ICF, and a summary of our understanding of laser-plasma interactions. A classified companion report contains material on our current understanding of capsule physics and lists the contributions to the Laboratory's weapons programs made by the ICF program. The information collected in these two volumes is meant to serve as a report on the status of some of the technological components of the Los Alamos ICF program rather than a detailed review of specific technical issues

  12. [Unnecessary routine laboratory tests in patients referred for surgical services].

    Science.gov (United States)

    Mata-Miranda, María del Pilar; Cano-Matus, Norberto; Rodriguez-Murrieta, Margarita; Guarneros-Zapata, Idalia; Ortiz, Mario

    2016-01-01

    To question the usefulness of the lab analysis considered routine testing for the identification of abnormalities in the surgical care. To determine the percentage of unnecessary laboratory tests in the preoperative assessment as well as to estimate the unnecessary expenses. A descriptive, cross-sectional study of patients referred for surgical evaluation between January 1st and March 31st 2013. The database of laboratory testing and electronic files were reviewed. Reference criteria from surgical services were compared with the tests requested by the family doctor. In 65% of the patients (n=175) unnecessary examinations were requested, 25% (n=68) were not requested the tests that they required, and only 10% of the patients were requested laboratory tests in accordance with the reference criteria (n=27). The estimated cost in unnecessary examinations was $1,129,552 in a year. The results were similar to others related to this theme, however, they had not been revised from the perspective of the first level of attention regarding the importance of adherence to the reference criteria which could prevent major expenditures. It is a priority for leaders and operational consultants in medical units to establish strategies and lines of action that ensure compliance with institutional policies so as to contain spending on comprehensive services, and which in turn can improve the medical care. Copyright © 2015 Academia Mexicana de Cirugía A.C. Published by Masson Doyma México S.A. All rights reserved.

  13. Third annual US Department of Energy review of laboratory programs for women

    Energy Technology Data Exchange (ETDEWEB)

    Perkins, L.; Engle, J.; Hassil, C. [eds.] [Oak Ridge Inst. for Science and Education, TN (United States)

    1993-12-31

    The Third Annual DOE Review of Laboratory Programs for Women was held May 11-13, 1993 at the Oak Ridge Institute for Science and Education (ORISE). The participants and organizers are men and women dedicted to highlighting programs that encourage women at all academic levels to consider career options in science, mathematics, and engineering. Cohosted by ORISE and the Oak Ridge National Laboratory (ORNL), the review was organized by an Oversight Committee whose goal was to develop an agenda and bring together concerned, skilled, and committed parties to discuss issues, make recommendations, and set objectives for the entire DOE community. Reports from each of six working groups are presented, including recommendations, objectives, descriptions, participants, and references.

  14. Initiation of depleted uranium oxide and spent fuel testing for the spent fuel sabotage aerosol ratio program

    Energy Technology Data Exchange (ETDEWEB)

    Molecke, M.A.; Gregson, M.W.; Sorenson, K.B. [Sandia National Labs. (United States); Billone, M.C.; Tsai, H. [Argonne National Lab. (United States); Koch, W.; Nolte, O. [Fraunhofer Inst. fuer Toxikologie und Experimentelle Medizin (Germany); Pretzsch, G.; Lange, F. [Gesellschaft fuer Anlagen- und Reaktorsicherheit (Germany); Autrusson, B.; Loiseau, O. [Inst. de Radioprotection et de Surete Nucleaire (France); Thompson, N.S.; Hibbs, R.S. [U.S. Dept. of Energy (United States); Young, F.I.; Mo, T. [U.S. Nuclear Regulatory Commission (United States)

    2004-07-01

    We provide a detailed overview of an ongoing, multinational test program that is developing aerosol data for some spent fuel sabotage scenarios on spent fuel transport and storage casks. Experiments are being performed to quantify the aerosolized materials plus volatilized fission products generated from actual spent fuel and surrogate material test rods, due to impact by a high energy density device, HEDD. The program participants in the U.S. plus Germany, France, and the U.K., part of the international Working Group for Sabotage Concerns of Transport and Storage Casks, WGSTSC have strongly supported and coordinated this research program. Sandia National Laboratories, SNL, has the lead role for conducting this research program; test program support is provided by both the U.S. Department of Energy and Nuclear Regulatory Commission. WGSTSC partners need this research to better understand potential radiological impacts from sabotage of nuclear material shipments and storage casks, and to support subsequent risk assessments, modeling, and preventative measures. We provide a summary of the overall, multi-phase test design and a description of all explosive containment and aerosol collection test components used. We focus on the recently initiated tests on ''surrogate'' spent fuel, unirradiated depleted uranium oxide, and forthcoming actual spent fuel tests. The depleted uranium oxide test rodlets were prepared by the Institut de Radioprotection et de Surete Nucleaire, in France. These surrogate test rodlets closely match the diameter of the test rodlets of actual spent fuel from the H.B. Robinson reactor (high burnup PWR fuel) and the Surry reactor (lower, medium burnup PWR fuel), generated from U.S. reactors. The characterization of the spent fuels and fabrication into short, pressurized rodlets has been performed by Argonne National Laboratory, for testing at SNL. The ratio of the aerosol and respirable particles released from HEDD-impacted spent

  15. Recent package testing successes at Oak Ridge National Laboratory

    International Nuclear Information System (INIS)

    Ludwig, S.B.; Singley, P.T.; Michelhaugh, R.D.; Hawk, M.B.; Shappert, L.B.

    2004-01-01

    Oak Ridge National Laboratory (ORNL)'s history of testing of radioactive material packages dates back to the early 1960s, and includes the testing of hundreds of different packages of all shapes and sizes. This paper provides an overview of ORNL's new Packaging Research Facility (PRF) at the National Transportation Research Center (NTRC), and describes recent package testing successes conducted at the NTRC from September 2002 to September 2003

  16. Error tracking in a clinical biochemistry laboratory

    DEFF Research Database (Denmark)

    Szecsi, Pal Bela; Ødum, Lars

    2009-01-01

    BACKGROUND: We report our results for the systematic recording of all errors in a standard clinical laboratory over a 1-year period. METHODS: Recording was performed using a commercial database program. All individuals in the laboratory were allowed to report errors. The testing processes were cl...

  17. [Contribution of HCV core antigen testing in HCV diagnosis by test from the company Abbott Laboratories].

    Science.gov (United States)

    Trbusek, J

    2009-11-01

    Detection of HCV core antigen as direct marker of hepatitis C infection clearly improves diagnosis of this disease (especially reduction of window period) and brings broad clinical utilization. The company Abbott Laboratories offers fully automated laboratory test for measurement of HCV core antigen on ARCHITECT analyzers.

  18. Standard test method for laboratory evaluation of magnesium sacrificial anode test specimens for underground applications

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    1997-01-01

    1.1 This test method covers a laboratory procedure that measures the two fundamental performance properties of magnesium sacrificial anode test specimens operating in a saturated calcium sulfate, saturated magnesium hydroxide environment. The two fundamental properties are electrode (oxidation potential) and ampere hours (Ah) obtained per unit mass of specimen consumed. Magnesium anodes installed underground are usually surrounded by a backfill material that typically consists of 75 % gypsum (CaSO4·2H2O), 20 % bentonite clay, and 5 % sodium sulfate (Na2SO4). The calcium sulfate, magnesium hydroxide test electrolyte simulates the long term environment around an anode installed in the gypsum-bentonite-sodium sulfate backfill. 1.2 This test method is intended to be used for quality assurance by anode manufacturers or anode users. However, long term field performance properties may not be identical to property measurements obtained using this laboratory test. Note 1—Refer to Terminology G 15 for terms used ...

  19. 42 CFR 493.1467 - Condition: Laboratories performing high complexity testing; cytology general supervisor.

    Science.gov (United States)

    2010-10-01

    ... testing; cytology general supervisor. 493.1467 Section 493.1467 Public Health CENTERS FOR MEDICARE....1467 Condition: Laboratories performing high complexity testing; cytology general supervisor. For the subspecialty of cytology, the laboratory must have a general supervisor who meets the qualification...

  20. Laboratory and field tests for radionuclide migration and high flow paths in clay

    International Nuclear Information System (INIS)

    Bourke, P.J.; Jefferies, N.L.; Lineham, T.R.; Nesirky, P.

    1991-01-01

    Two investigations have been undertaken in this programme. The principal investigation was at Culham Laboratory, England, where water flow within the Kimmeridge clay was measured. A subsidiary investigation at SCK/CEN was undertaken at the Underground Research Laboratory SCK/CEN Mol, Belgium, where an in situ measurement of solute transport by diffusion was attempted. The in situ migration experiment at the Underground Research Laboratory at SCK/CEN Mol, Belgium, was unsuccessful, due to problems with the engineering installation. These difficulties caused significant disturbance to the Boom clay which was to be tested. Nevertheless the laboratory test proved the feasibility of the experiment. The field measurements at Culham Laboratory, Oxfordshire, were completed with the flow testing of a very silty clay horizon in the Kimmeridge clay. This layer was proved to be laterally continuous after drilling three exploratory boreholes. The hydraulic conductivity of the layer was ≥ 10 -8 ms -1 and comparative tests in the clay showed the conductivity of the clay to be at least 50 times less. 12 figs

  1. Expert Assessment of Conditions for Accredited Quality Management System Functioning in Testing Laboratories

    Science.gov (United States)

    Mytych, Joanna; Ligarski, Mariusz J.

    2018-03-01

    The quality management systems compliant with the ISO 9001:2009 have been thoroughly researched and described in detail in the world literature. The accredited management systems used in the testing laboratories and compliant with the ISO/IEC 17025:2005 have been mainly described in terms of the system design and implementation. They have also been investigated from the analytical point of view. Unfortunately, a low number of studies concerned the management system functioning in the accredited testing laboratories. The aim of following study was to assess the management system functioning in the accredited testing laboratories in Poland. On 8 October 2015, 1,213 accredited testing laboratories were present in Poland. They investigated various scientific areas and substances/objects. There are more and more such laboratories that have various problems and different long-term experience when it comes to the implementation, maintenance and improvement of the management systems. The article describes the results of the conducted expert assessment (survey) carried out to examine the conditions for the functioning of a management system in an accredited laboratory. It also focuses on the characteristics of the accredited research laboratories in Poland. The authors discuss the selection of the external and internal conditions that may affect the accredited management system. They show how the experts assessing the selected conditions were chosen. The survey results are also presented.

  2. Response Matrix Method Development Program at Savannah River Laboratory

    International Nuclear Information System (INIS)

    Sicilian, J.M.

    1976-01-01

    The Response Matrix Method Development Program at Savannah River Laboratory (SRL) has concentrated on the development of an effective system of computer codes for the analysis of Savannah River Plant (SRP) reactors. The most significant contribution of this program to date has been the verification of the accuracy of diffusion theory codes as used for routine analysis of SRP reactor operation. This paper documents the two steps carried out in achieving this verification: confirmation of the accuracy of the response matrix technique through comparison with experiment and Monte Carlo calculations; and establishment of agreement between diffusion theory and response matrix codes in situations which realistically approximate actual operating conditions

  3. Policies and practices in haemostasis testing among laboratories in Croatia: a survey on behalf of a Working Group for Laboratory Coagulation of the Croatian Society of Medical Biochemistry and Laboratory Medicine.

    Science.gov (United States)

    Bronić, Ana; Herak, Desiree Coen; Margetić, Sandra; Milić, Marija

    2017-02-15

    The objective of this survey was to assess current policies and practice in haemostasis testing among both hospital and outpatient laboratories in Republic of Croatia. A questionnaire with seventy questions divided into nine sections was created in May 2015. Participants were asked about their practice related to test request form, sample collection, prothrombin time (PT) and activated partial thromboplastin time assays, other individual haemostasis assays, point-of-care testing (POCT), reporting of coagulation tests results and quality assurance of procedures, the personnel and other laboratory resources, as well as on issues related to education and implementation of additional coagulation assays in their laboratory. The survey was administered and data were collected between June and September 2015. A total survey response rate was 104/170 (61.2%). Most respondents were faced with incomplete information on prescribed therapy and diagnosis on the test request or inappropriate samples withdrawn on distant locations, but also do not have protocols for handling samples with high haematocrit values. Reporting of PT-INR and D-dimer results was different between laboratories. Although almost all laboratories developed a critical value reporting system, reporting a value to general practitioners is still a problem. Result on coagulation POCT testing showed that not all devices were supervised by laboratories, which is not in compliance with Croatian Chamber of Medical Biochemistry acts. Obtained results highlighted areas that need improvement and different practice patterns in particular field of haemostasis testing among laboratories. A harmonization of the overall process of haemostasis testing at national level should be considered and undertaken.

  4. Diagnostic and laboratory test ordering in Northern Portuguese Primary Health Care: a cross-sectional study

    Science.gov (United States)

    Sá, Luísa; Teixeira, Andreia Sofia Costa; Tavares, Fernando; Costa-Santos, Cristina; Couto, Luciana; Costa-Pereira, Altamiro; Hespanhol, Alberto Pinto; Santos, Paulo

    2017-01-01

    Objectives To characterise the test ordering pattern in Northern Portugal and to investigate the influence of context-related factors, analysing the test ordered at the level of geographical groups of family physicians and at the level of different healthcare organisations. Design Cross-sectional study. Setting Northern Primary Health Care, Portugal. Participants Records about diagnostic and laboratory tests ordered from 2035 family physicians working at the Northern Regional Health Administration, who served approximately 3.5 million Portuguese patients, in 2014. Outcomes To determine the 20 most ordered diagnostic and laboratory tests in the Northern Regional Health Administration; to identify the presence and extent of variations in the 20 most ordered diagnostic and laboratory tests between the Groups of Primary Care Centres and between health units; and to study factors that may explain these variations. Results The 20 most ordered diagnostic and laboratory tests almost entirely comprise laboratory tests and account for 70.9% of the total tests requested. We can trace a major pattern of test ordering for haemogram, glucose, lipid profile, creatinine and urinalysis. There was a significant difference (P<0.001) in test orders for all tests between Groups of Primary Care Centres and for all tests, except glycated haemoglobin (P=0.06), between health units. Generally, the Personalised Healthcare Units ordered more than Family Health Units. Conclusions The results from this study show that the most commonly ordered tests in Portugal are laboratory tests, that there is a tendency for overtesting and that there is a large variability in diagnostic and laboratory test ordering in different geographical and organisational Portuguese primary care practices, suggesting that there may be considerable potential for the rationalisation of test ordering. The existence of Family Health Units seems to be a strong determinant in decreasing test ordering by Portuguese family

  5. Laboratory services series: a safety program for service groups in a national research and development laboratory (1965--1974)

    International Nuclear Information System (INIS)

    Winget, R.H.

    1975-11-01

    The experiences of a ten-year period of developing a safety program for craft and labor groups supporting a major laboratory are summarized with tabulations of types of injuries or accidents, improvements noted over the decade, and educational and safety recognition efforts

  6. Sandia National Laboratories support of the Iraq Nuclear Facility Dismantlement and Disposal Program.

    Energy Technology Data Exchange (ETDEWEB)

    Cochran, John Russell; Danneels, Jeffrey John

    2009-03-01

    -25, 2008. As noted in the report, there was significant teaming between the various participants to best help the GOI. On-the-ground progress is the focus of the Iraq NDs Program and much of the work is a transfer of technical and practical skills and knowledge that Sandia uses day-to-day. On-the-ground progress was achieved in July of 2008 when the GOI began the physical cleanup and dismantlement of the Active Metallurgical Testing Laboratory (LAMA) facility at Al Tuwaitha, near Baghdad.

  7. Personal dosimetry performance testing in the United States

    International Nuclear Information System (INIS)

    Soares, Christopher G.

    2008-01-01

    The basis for personal dosimetry performance testing in the United States is ANSI/HPS N13.11. Now in it's fourth edition, this standard has been in place since 1983. Testing under this standard is administered by the National Voluntary Laboratory Accreditation Program (NVLAP), and accreditation of dosimetry processors under this program is required by U.S. Nuclear Regulatory Commission (NRC) regulations. The U.S. Department of Energy (DOE) also maintains a testing program for its laboratories and contractors, administered by the Department of Energy Laboratory Accreditation Program (DOELAP). One of the goals of this current revision was the modification of ANSI/HPS N13.11 to allow acceptance by both testing programs in order to bring harmonization to U.S. personal dosemeter performance testing. The testing philosophy of ANSI/HPS N13.11 has always combined elements of type testing and routine performance testing and is thus different from the testing philosophy used in the rest of the world. In this paper, the history of performance testing in the U.S. is briefly reviewed. Also described is the revision that produced the fourth edition of this standard, which has taken place over the last three years (2005-2008) by a working group representing national standards laboratories, government laboratories, the military, dosimetry vendors, universities and the nuclear power industry. (author)

  8. The New Brunswick Laboratory Safeguards Measurement Evaluation Program

    International Nuclear Information System (INIS)

    Cacic, C.G.; Trahey, N.M.; Zook, A.C.

    1987-01-01

    The New Brunswick Laboratory (NBL) has been tasked by the U.S. Department of Energy (DOE) Office of Safeguards and Security (OSS) to assess and evaluate the adequacy of measurement technology as applied to materials accounting in DOE nuclear facilities. The Safeguards Measurement Evaluation (SME) Program was developed as a means to monitor and evaluate the quality and effectiveness of accounting measurements by site, material balance area (MBA), or unit process. Phase I of the SME Program, initiated during 1985, involved evaluation of the primary accountability measurement methods at six DOE Defense Programs facilities: Savannah River Plant, Portsmouth Gaseous Diffusion Plant, Y-12 Plant, Rocky Flats Plant, Rockwell Hanford Operations, and NBL. Samples of uranyl nitrate solution, dried plutonium nitrates, and plutonium oxides were shipped to the participants for assay and isotopic abundance measurements. Resulting data are presented and evaluated as indicators of current state-of-the-practice accountability measurement methodology, deficiencies in materials accounting practices, and areas for possible assistance in upgrading measurement capabilities. Continuing expansion of the SME Program to include materials which are representative of specific accountability measurement points within the DOE complex is discussed

  9. Real-time laboratory exercises to test contingency plans for classical swine fever: experiences from two national laboratories

    DEFF Research Database (Denmark)

    Koenen, K.; Uttenthal, Åse; Meindl-Böhmer, A.

    2007-01-01

    In order to adequately and efficiently handle outbreaks of contagious diseases such as classical swine fever (CSF), foot and mouth disease or highly pathogenic avian influenza, competent authorities and the laboratories involved have to be well prepared and must be in possession of functioning....... It is essential that these plans are established during ‘peace-time’ and are reviewed regularly. This paper provides suggestions on how to perform laboratory exercises to test preparedness and describes the experiences of two national reference laboratories for CSF. The major lesson learnt was the importance...

  10. Crush Testing at Oak Ridge National Laboratory

    International Nuclear Information System (INIS)

    Feldman, Matthew R.

    2011-01-01

    The dynamic crush test is required in the certification testing of some small Type B transportation packages. International Atomic Energy Agency regulations state that the test article must be 'subjected to a dynamic crush test by positioning the specimen on the target so as to suffer maximum damage.' Oak Ridge National Laboratory (ORNL) Transportation Technologies Group performs testing of Type B transportation packages, including the crush test, at the National Transportation Research Center in Knoxville, Tennessee (United States). This paper documents ORNL's experiences performing crush tests on several different Type B packages. ORNL has crush tested five different drum-type package designs, continuing its 60 year history of RAM package testing. A total of 26 crush tests have been performed in a wide variety of package orientations and crush plate CG alignments. In all cases, the deformation of the outer drum created by the crush test was significantly greater than the deformation damage caused by the 9 m drop test. The crush test is a highly effective means for testing structural soundness of smaller nondense Type B shipping package designs. Further regulatory guidance could alleviate the need to perform the crush test in a wide range of orientations and crush plate CG alignments.

  11. Improving communication skill training in patient centered medical practice for enhancing rational use of laboratory tests: The core of bioinformation for leveraging stakeholder engagement in regulatory science.

    Science.gov (United States)

    Moura, Josemar de Almeida; Costa, Bruna Carvalho; de Faria, Rosa Malena Delbone; Soares, Taciana Figueiredo; Moura, Eliane Perlatto; Chiappelli, Francesco

    2013-01-01

    Requests for laboratory tests are among the most relevant additional tools used by physicians as part of patient's health problemsolving. However, the overestimation of complementary investigation may be linked to less reflective medical practice as a consequence of a poor physician-patient communication, and may impair patient-centered care. This scenario is likely to result from reduced consultation time, and a clinical model focused on the disease. We propose a new medical intervention program that specifically targets improving the patient-centered communication of laboratory tests results, the core of bioinformation in health care. Expectations are that medical students training in communication skills significantly improve physicians-patient relationship, reduce inappropriate use of laboratorial tests, and raise stakeholder engagement.

  12. PWR Users Group 10 CFR 61 Waste Form Requirements Compliance Test Program