Gas release and leachates at bark storage: Laboratory and field studies. Final report

International Nuclear Information System (INIS)

Jirjis, Raida; Andersson, Paal; Aronsson, Paer

2005-01-01

Large volumes of bark are produced as a by-product from saw mills and pulp and paper industry all year round in Sweden. Most of the bark is used as a biofuel. Due to the uneven demand for the fuel during the year, bark has to be often stored for a few months. Storage normally takes place outdoors in fairly large piles. A number of biological and chemical processes are known to occur during storage. These processes can lead to the emission and leakage of environmentally unaccepted products which can also affect working environment. The aim of this project was to evaluate the outcome of some of these processes and to asses its effect on working environment as well as the surrounding environment. This study investigates the storage of fresh bark from pine and spruce in laboratory scale experiments and a large scale storage trial. Results of the analyses of bark material, before and after storage, and the chemical constituents of the released gases and leached material are presented. Estimation of the total amounts that can be released in gas form or leached out from bark piles during storage, and possible environmental consequences are discussed. Conclusions and some practical suggestion concerning bark storage are given in this report. The laboratory experiment involved storage of fresh bark in a 34 litres cylindrical chamber at room temperature (RT) or heated to an average of 55 deg C. The chambers were designed to provide gas samples during emissions experiment and allow irrigation during leakage experiments. Sampling of the released gases (using Tenax-adsorbent) was performed during two or three weeks of storage for spruce and pine bark respectively. The total volatile organic compounds (VOC) and individual monoterpenes were determined. Changes in the chemical constituents of bark during storage were studied using different extraction methods and measuring instruments including Gas spectroscopy (GC)-flame ionization detector (FID) and GC- mass spectroscopy (MS

Phase B: Final definition and preliminary design study for the initial Atmospheric Cloud Physics Laboratory (ACPL): A spacelab mission payload. Final review (DR-MA-03)

Science.gov (United States)

Clausen, O. W.

1976-01-01

Systems design for an initial atmospheric cloud physics laboratory to study microphysical processes in zero gravity is presented. Included are descriptions of the fluid, thermal, mechanical, control and data, and electrical distribution interfaces with Spacelab. Schedule and cost analysis are discussed.

Decontamination and decommissioning of the Experimental Boiling Water Reactor (EBWR): Project final report, Argonne National Laboratory

International Nuclear Information System (INIS)

Fellhauer, C.R.; Boing, L.E.; Aldana, J.

1997-03-01

The Final Report for the Decontamination and Decommissioning (D ampersand D) of the Argonne National Laboratory - East (ANL-E) Experimental Boiling Water Reactor (EBWR) facility contains the descriptions and evaluations of the activities and the results of the EBWR D ampersand D project. It provides the following information: (1) An overall description of the ANL-E site and EBWR facility. (2) The history of the EBWR facility. (3) A description of the D ampersand D activities conducted during the EBWR project. (4) A summary of the final status of the facility, including the final and confirmation surveys. (5) A summary of the final cost, schedule, and personnel exposure associated with the project, including a summary of the total waste generated. This project report covers the entire EBWR D ampersand D project, from the initiation of Phase I activities to final project closeout. After the confirmation survey, the EBWR facility was released as a open-quotes Radiologically Controlled Area,close quotes noting residual elevated activity remains in inaccessible areas. However, exposure levels in accessible areas are at background levels. Personnel working in accessible areas do not need Radiation Work Permits, radiation monitors, or other radiological controls. Planned use for the containment structure is as an interim transuranic waste storage facility (after conversion)

Assessing the outcome of Strengthening Laboratory Management Towards Accreditation (SLMTA) on laboratory quality management system in city government of Addis Ababa, Ethiopia.

Science.gov (United States)

Sisay, Abay; Mindaye, Tedla; Tesfaye, Abrham; Abera, Eyob; Desale, Adino

2015-01-01

Strengthening Laboratory Management Toward Accreditation (SLMTA) is a competency-based management training programme designed to bring about immediate and measurable laboratory improvement. The aim of this study is to assess the outcome of SLMTA on laboratory quality management system in Addis Ababa, Ethiopia. The study used an Institutional based cross sectional study design that employed a secondary and primary data collection approach on the participated institution of medical laboratory in SLMTA. The study was conducted in Addis Ababa city government and the data was collected from February 'April 2014 and data was entered in to EPI-data version 3.1 and was analyzed by SPSS version 20. The assessment finding indicate that there was a significant improvement in average scores (141.4; range of 65-196, 95%CI=86.275-115.5, p=0.000) at final with 3 laboratories become 3 star, 6 laboratories were at 2 star, 11 were 1 star. Laboratory facilities respondents which thought getting adequate and timely manner mentorship were found 2.5 times more likely to get good success in the final score(AOR=2.501, 95% CI=1.109-4.602) than which did not get it. At the end of SLMTA implementation,3 laboratories score 3 star, 6 laboratories were at 2 star, 11 were at 1 star. The most important contributing factor for not scoring star in the final outcome of SLMTA were not conducting their customer satisfaction survey, poor staff motivation, and lack of regular equipment service maintenance. Mentorship, onsite and offsite coaching and training activities had shown a great improvement on laboratory quality management system in most laboratories.

Self-sealing barriers of sand/bentonite-mixtures in a clay repository. SB-experiment in the Mont Terri Rock Laboratory. Final report

International Nuclear Information System (INIS)

Rothfuchs, Tilmann; Czaikowski, Oliver; Hartwig, Lothar; Hellwald, Karsten; Komischke, Michael; Miehe, Ruediger; Zhang, Chun-Liang

2012-10-01

Several years ago, GRS performed laboratory investigations on the suitability of clay/mineral mixtures as optimized sealing materials in underground repositories for radioactive wastes /JOC 00/ /MIE 03/. The investigations yielded promising results so that plans were developed for testing the sealing properties of those materials under representative in-situ conditions in the Mont Terri Rock Laboratory (MTRL). The project was proposed to the ''Projekttraeger Wassertechnologie und Entsorgung (PtWT+E)'', and finally launched in January 2003 under the name SB-project (''Self-sealing Barriers of Clay/Mineral Mixtures in a Clay Repository''). The project was divided in two parts, a pre-project running from January 2003 until June 2004 under contract No. 02E9713 /ROT 04/ and the main project running from January 2004 until June 2012 under contract No. 02E9894 with originally PtWT+E, later renamed as PTKA-WTE. In the course of the pre-project it was decided to incorporate the SB main project as a cost shared action of PtWT+E and the European Commission (contract No. FI6W-CT-2004-508851) into the EC Integrated Project ESDRED (Engineering Studies and Demonstrations of Repository Designs) performed by 11 European project partners within the 6th European framework programme. The ESDRED project was terminated prior to the termination of the SB project. Interim results were reported by mid 2009 in two ESDRED reports /DEB09/ /SEI 09/. This report presents the results achieved in the whole SB-project comprising preceding laboratory investigations for the final selection of suited material mixtures, the conduction of mock-up tests in the geotechnical laboratory of GRS in Braunschweig and the execution of in-situ experiments at the MTRL.

Laboratory Studies of Atmospheric Heterogeneous Chemistry

Science.gov (United States)

Keyser, L. F.; Leu, M-T.

1993-01-01

In the laboratory, ice films formed by freezing from the liquid or more frequently by deposition from the vapor phase have been used to simulate stratospheric cloud surfaces for measurements of reaction and uptake rates. To obtain intrinsic surface reaction probabilities that can be used in atmospheric models, the area of the film surface that actually takes part in the reaction must be known. It is important to know not only the total surface area but also the film morphology in order to determine where and how the surface is situated and, thus, what fraction of it is available for reaction. Information on the structure of these ice films has been obtained by using several experimental methods. In the sections that follow, these methods will be discussed, then the results will be used to construct a working model of the ice films, and finally the model will be applied to an experimental study of HC1 uptake by H_2O ice.

The Orthopaedic Training Study, Phase II 1968-1972. Final Report Supplement, Psychomotor Skills, Part B.

Science.gov (United States)

Olson, Carl J.; And Others

This document, as a supplement to the final report of the Orthopaedic Training Study, presents a discussion of the rationale behind the implementation of a laboratory course in psychomotor skills development for medical students. Medical educators examined resident training in terms of 3 components of cognitive elements of learning: cognitive,…

Final Report National Laboratory Professional Development Workshop for Underrepresented Participants

Energy Technology Data Exchange (ETDEWEB)

Taylor, Valerie [Texas Engineering Experiment Station, College Station, TX (United States)

2016-11-07

The 2013 CMD-IT National Laboratories Professional Development Workshop for Underrepresented Participants (CMD-IT NLPDev 2013) was held at the Oak Ridge National Laboratory campus in Oak Ridge, TN. from June 13 - 14, 2013. Sponsored by the Department of Energy (DOE) Advanced Scientific Computing Research Program, the primary goal of these workshops is to provide information about career opportunities in computational science at the various national laboratories and to mentor the underrepresented participants through community building and expert presentations focused on career success. This second annual workshop offered sessions to facilitate career advancement and, in particular, the strategies and resources needed to be successful at the national laboratories.

DOE Los Alamos National Laboratory – PV Feasibility Assessment, 2015 Update, NREL Final Report

Energy Technology Data Exchange (ETDEWEB)

Dean, Jesse [National Renewable Energy Lab. (NREL), Golden, CO (United States); Witt, Monica Rene [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2016-04-06

This report summarizes solar and wind potential for Los Alamos National Laboratory (LANL). This report is part of the “Los Alamos National Laboratory and Los Alamos County Renewable Generation” study.

Laboratory microfusion capability study

International Nuclear Information System (INIS)

1993-05-01

The purpose of this study is to elucidate the issues involved in developing a Laboratory Microfusion Capability (LMC) which is the major objective of the Inertial Confinement Fusion (ICF) program within the purview of the Department of Energy's Defense Programs. The study was initiated to support a number of DOE management needs: to provide insight for the evolution of the ICF program; to afford guidance to the ICF laboratories in planning their research and development programs; to inform Congress and others of the details and implications of the LMC; to identify criteria for selection of a concept for the Laboratory Microfusion Facility and to develop a coordinated plan for the realization of an LMC. As originally proposed, the LMC study was divided into two phases. The first phase identifies the purpose and potential utility of the LMC, the regime of its performance parameters, driver independent design issues and requirements, its development goals and requirements, and associated technical, management, staffing, environmental, and other developmental and operational issues. The second phase addresses driver-dependent issues such as specific design, range of performance capabilities, and cost. The study includes four driver options; the neodymium-glass solid state laser, the krypton fluoride excimer gas laser, the light-ion accelerator, and the heavy-ion induction linear accelerator. The results of the Phase II study are described in the present report

Study of the atmospheric chemistry of radon progeny in laboratory and real indoor atmospheres. Final project report

International Nuclear Information System (INIS)

Hopke, P.K.

1996-09-01

This report completes Clarkson University's study of the chemical and physical behavior of the 218 Po atom immediately following its formation by the alpha decay of radon. Because small changes in size for activity in the sub-10 nm size range result in large changes in the delivered dose per unit exposure, this behavior must be understood if the exposure to radon progeny and it dose to the cells in the respiratory tract are to be fully assessed. In order to pursue this general goal, two areas of radon progeny behavior are being pursued; laboratory studies under controlled conditions to better understand the fundamental physical and chemical processes that affect the progeny's atmospheric behavior and studies in actual indoor environments to develop a better assessment of the exposure of the occupants of that space to the size and concentration of the indoor radioactive aerosol. Thus, two sets of specific goals have been established for this project. The specific tasks of the controlled laboratory studies are (1) Determine the formation rates of circ OH radicals formed by the radiolysis of air following radon decay; (2) Examine the formation of particles by the radiolytic oxidation of substances like SO 2 , ethylene, and H 2 S to lower vapor pressure compounds and determine the role of gas phase additives such as H 2 O and NH 3 in determining the particle size; (3) Measure the rate of ion-induced nucleation using a thermal diffusion cloud chamber, and (4) Measure the neutralization rate of 218 PoO x + in O 2 at low radon concentrations

Los Alamos National Laboratory plans for a laboratory microfusion facility

International Nuclear Information System (INIS)

Harris, D.B.

1988-01-01

Los Alamos National Laboratory is actively participating in the National Laboratory Microfusion Facility (LMF) Scoping Study. We are currently performing a conceptual design study of a krypton-fluoride laser system that appears to meet all of the diver requirements for the LMF. A new theory of amplifier module scaling has been developed recently and it appears that KrF amplifier modules can be scaled up to output energies much larger than thought possible a few years ago. By using these large amplifier modules, the reliability and availability of the system is increased and its cost and complexity is decreased. Final cost figures will be available as soon as the detailed conceptual design is complete

ZERT Final Scientific Report Los Alamos National Laboratory

Energy Technology Data Exchange (ETDEWEB)

Pawar, Rajesh J. [Los Alamos National Laboratory

2011-01-01

Los Alamos National Laboratory's (LANL) activities for the Center for Zero Emission Research and Technology (ZERT) have fallen into three broad research areas: (1) How do you reduce uncertainty in assuring prior to operation that an engineered geologic site will meet a specific performance goal (e.g., <0.01% leak per year)? (2) What are key monitoring needs for verifying that an engineered geologic site is meeting a performance goal? (3) What are potential vulnerabilities for breeches in containment of CO{sub 2}, and how could they be mitigated either prior to operation or in the event that a threshold is exceeded? We have utilized LANL's multi-disciplinary expertise and an integrated approach combining laboratory experiments, field observations and numerical simulations to address various research issues related to above-mentioned areas. While there have been a number of major milestones achieved as described in past quarterly reports, two of the major accomplishments resulting from LANL's efforts include: (1) Development of the CO{sub 2}-PENS systems framework for long-term performance analysis of geologic CO{sub 2} sequestration sites. CO{sub 2}-PENS is first-ever systems analysis tool designed for assessment of CO{sub 2} sequestration sites. (2) One of the few field studies to-date focused on understanding impact of CO{sub 2} leakage on shallow groundwater chemistry. Two major conclusions of the study are as follows: the impact of co-contaminants transported with deeper brine on shallow groundwater quality is likely to be much larger than that of the CO{sub 2} and CO{sub 2}-induced geochemical reactions and in certain geochemical environment the reactivity of pure CO{sub 2} will not be sufficient to mobilize metals beyond background levels.

Physics Laboratory technical activities, 1991. Final report

International Nuclear Information System (INIS)

Gebbie, K.B.

1992-02-01

The report summarizes research projects, measurement method development, calibration and testing, and data evaluation activities that were carried out during calendar year 1991 in the NIST Physics Laboratory. These activities fall in the areas of electron and optical physics, atomic physics, molecular physics, radiometric physics, quantum metrology, ionizing radiation, time and frequency, quantum physics, and fundamental constants

KEY COMPARISON: Final report of comparison of the calibrations of hydrometers for liquid density determination between SIM laboratories: SIM.M.D-K4

Science.gov (United States)

Becerra, Luis Omar

2009-01-01

This SIM comparison on the calibration of high accuracy hydrometers was carried out within fourteen laboratories in the density range from 600 kg/m3 to 1300 kg/m3 in order to evaluate the degree of equivalence among participant laboratories. This key comparison anticipates the planned key comparison CCM.D-K4, and is intended to be linked with CCM.D-K4 when results are available. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).

Virtual reality studies outside the laboratory

DEFF Research Database (Denmark)

Mottelson, Aske; Hornbæk, Kasper

2017-01-01

virtual reality (VR) studies outside laboratories remains unclear because these studies often use expensive equipment, depend critically on the physical context, and sometimes study delicate phenomena concerning body awareness and immersion. To investigate, we explore pointing, 3D tracing, and body......Many user studies are now conducted outside laboratories to increase the number and heterogeneity of participants. These studies are conducted in diverse settings, with the potential to give research greater external validity and statistical power at a lower cost. The feasibility of conducting......-illusions both in-lab and out-of-lab. The in-lab study was carried out as a traditional experiment with state-of-the-art VR equipment; 31 completed the study in our laboratory. The out-of-lab study was conducted by distributing commodity cardboard VR glasses to participants; 57 completed the study anywhere...

Tank 103, 219-S Facility at 222-S Laboratory, analytical results for the final report

International Nuclear Information System (INIS)

Fuller, R.K.

1998-01-01

This is the final report for the polychlorinated biphenyls analysis of Tank-103 (TK-103) in the 219-S Facility at 222-S Laboratory. Twenty 1-liter bottles (Sample numbers S98SO00074 through S98SO00093) were received from TK-103 during two sampling events, on May 5 and May 7, 1998. The samples were centrifuged to separate the solids and liquids. The centrifuged sludge was analyzed for PCBs as Aroclor mixtures. The results are discussed on page 6. The sample breakdown diagram (Page 114) provides a cross-reference of sample identification of the bulk samples to the laboratory identification number for the solids. The request for sample analysis (RSA) form is provided as Page 117. The raw data is presented on Page 43. Sample Description, Handling, and Preparation Twenty samples were received in the laboratory in 1-Liter bottles. The first 8 samples were received on May 5, 1998. There were insufficient solids to perform the requested PCB analysis and 12 additional samples were collected and received on May 7, 1998. Breakdown and sub sampling was performed on May 8, 1998. Sample number S98SO00084 was lost due to a broken bottle. Nineteen samples were centrifuged and the solids were collected in 8 centrifuge cones. After the last sample was processed, the solids were consolidated into 2 centrifuge cones. The first cone contained 9.7 grams of solid and 13.0 grams was collected in the second cone. The wet sludge from the first centrifuge cone was submitted to the laboratory for PCB analysis (sample number S98SO00102). The other sample portion (S98SO00103) was retained for possible additional analyses

The ATLAS project: The effects of a constructionist digital laboratory project on undergraduate laboratory performance.

Science.gov (United States)

Shoepe, Todd C; Cavedon, Dana K; Derian, Joseph M; Levy, Celine S; Morales, Amy

2015-01-01

Anatomical education is a dynamic field where developments in the implementation of constructive, situated-learning show promise in improving student achievement. The purpose of this study was to examine the effectiveness of an individualized, technology heavy project in promoting student performance in a combined anatomy and physiology laboratory course. Mixed-methods research was used to compare two cohorts of anatomy laboratories separated by the adoption of a new laboratory atlas project, which were defined as preceding (PRE) and following the adoption of the Anatomical Teaching and Learning Assessment Study (ATLAS; POST). The ATLAS project required the creation of a student-generated, photographic atlas via acquisition of specimen images taken with tablet technology and digital microscope cameras throughout the semester. Images were transferred to laptops, digitally labeled and photo edited weekly, and compiled into a digital book using Internet publishing freeware for final project submission. An analysis of covariance confirmed that student final examination scores were improved (P project (PRE, n = 75; POST, n = 90; means ± SE; 74.9 ± 0.9 versus 78.1 ± 0.8, respectively) after controlling for cumulative student grade point average. Analysis of questionnaires collected (n = 68) from the post group suggested students identified with atlas objectives, appreciated the comprehensive value in final examination preparation, and the constructionism involved, but recommended alterations in assignment logistics and the format of the final version. Constructionist, comprehensive term-projects utilizing student-preferred technologies could be used to improve performance toward student learning outcomes. © 2014 American Association of Anatomists.

Catalytic Two-Stage Liquefaction (CTSL{trademark}) process: Laboratory scale studies modelling and technical assessment. Final report, [October 1, 1988--June 30, 1993

Energy Technology Data Exchange (ETDEWEB)

Comolli, A.G.; Johanson, E.S.; Lee, L.K.; Popper, G.A.; Smith, T.O.

1993-06-01

Reported herein are the details and results of Laboratory-Scale experiments using sub-bituminous and bituminous coal concluded at Hydrocarbon Research, Inc., under DOE Contract No. AC22-88PCB8818 during the period October 1, 1988 to June 30, 1993. The work described in this report is primarily concerned with tests on a Laboratory Scale primarily using microautoclaves. Experiments were conducted evaluating coal, solvents, start-up oils, catalysts, thermal treatments, C0{sub 2} addition and sulfur compound effects. Other microautoclave tests are included in the companion topical reports for this contract, DE-88818-TOP-01 & 02 on Sub-Bituminous and Bituminous Bench-Scale and PDU activities. In addition to the Laboratory Scale Studies, kinetic data and modelling results from Bench-Scale and Microautoclave tests are interpreted and presented along with some economic updates and sensitivity studies.

Zero-gravity cloud physics laboratory: Experiment program definition and preliminary laboratory concept studies

Science.gov (United States)

Eaton, L. R.; Greco, E. V.

1973-01-01

The experiment program definition and preliminary laboratory concept studies on the zero G cloud physics laboratory are reported. This program involves the definition and development of an atmospheric cloud physics laboratory and the selection and delineations of a set of candidate experiments that must utilize the unique environment of zero gravity or near zero gravity.

Commercialization of Los Alamos National Laboratory technologies via small businesses. Final report

Energy Technology Data Exchange (ETDEWEB)

Brice, R.; Carton, D.; Rhyne, T. [and others

1997-06-01

Appendices are presented from a study performed on a concept model system for the commercialization of Los Alamos National Laboratory technologies via small businesses. Topics include a summary of information from the joint MCC/Los Alamos technology conference; a comparison of New Mexico infrastructure to other areas; a typical licensing agreement; technology screening guides; summaries of specific DOE/UC/Los Alamos documents; a bibliography; the Oak Ridge National Laboratory TCRD; The Ames Center for Advanced Technology Development; Los Alamos licensing procedures; presentation of slides from monthly MCC/Los Alamos review meetings; generalized entrepreneurship model; and a discussion on receiving equity for technology.

Hertelendi Laboratory of Environmental Studies

International Nuclear Information System (INIS)

Svingor, E.; Molnar, M.; Palcsu, L.; Futo, I.; Rinyu, L.; Mogyorosi, M.; Major, Z.; Bihari, A.; Vodila, G.; Janovics, R.; Papp, L.; Major, I.

2010-01-01

1. Introduction. The Hertelendi Laboratory for Environmental Studies (HEKAL) belongs to the Section of Environmental and Earth Sciences. It is a multidisciplinary laboratory dedicated to environmental research, to the development of nuclear analytical methods and to systems technology. During its existence of more than 15 years it has gained some reputation as a prime laboratory of analytical techniques, working with both radio- and stable isotopes. It has considerable expertise in isotope concentration measurements, radiocarbon dating, tritium measurements, in monitoring radioactivity around nuclear facilities and in modelling the movement of radionuclides in the environment. Many of its projects are within the scope of interest of the Paks Nuclear Power Plant. Our research activity is mainly concerned with the so-called environmental isotopes. This term denotes isotopes, both stable and radioactive, that are present in the natural environment either as a result of natural processes or of human activities. In environmental research isotopes are generally applied either as tracers or as age indicators. An ideal tracer is defined as a substance that behaves in the system studied exactly as the material to be traced as far as the examined parameters are concerned, but has at least one property that distinguishes it from the traced material. The mass number of an isotope is such an ideal indicator. In 2007 the laboratory assumed the name of Dr. Ede Hertelendi to honour the memory of the reputed environmental physicist who founded the group and headed it for many years. The current core of the laboratory staff is made up of his pupils and coworkers. This team was like a family to him. The group owes it to his fatherly figure that it did not fall apart after his death, but advanced with intense work and tenacity during the last decade. One of his first pupils, Mihaly Veres returned to the laboratory as a private entrepreneur and investor in 2005, and in the framework of

Termination of the Special Metallurgical (SM) Building at Mound Laboratory: a final report

International Nuclear Information System (INIS)

Harris, W.R.; Kokenge, B.R.; Marsh, G.C.

1976-01-01

The report describes and highlights the more important factors associated with the termination of the Special Metallurgical (SM) Building at Mound Laboratory. As a result, a written record of the more important techniques and procedures is now available for reference by others involved in similar termination efforts. Included in this report is a description of the organizational units that were used in this effort along with a description of their responsibilities. A general description of the SM Building and a discussion of the more relevant procedures and equipment that were used are also presented. In addition, pertinent Health Physics information, such as personnel exposure, final wipe levels in the terminated facility, and assays of the structure, are provided. Based on the experience gained from this project, recommendations were made regarding the design of future radioactive material handling facilities so that when they are ultimately terminated the effort can be accomplished more efficiently

Noise study in laboratories with exhaust fans

International Nuclear Information System (INIS)

Shaikh, G.H.; Hashmi, R.; Shareef, A.

2005-01-01

Noise study has been carried out in 25 laboratories fitted with exhaust fans. We have studied A- Weighted equivalent sound pressure levels (dB(A) LAeJ and equivalent octave band sound pressure levels (dB L/sub eq/ in each of the laboratories surveyed. The data collected has been analyzed for Preferred Speech Interference Levels (PSIL). The results show that the interior noise levels in these laboratories vary from 59.6 to 72.2 dB(A) L/sub Aeq/, which are very high and much beyond the interior noise limits recommended for laboratories. Some ways and means to limit emission of high-level noise from exhaust fans are also discussed. (author)

Final Technical Report. Origins of subsurface microorganisms: Relating laboratory microcosm studies to a geologic time scale; FINAL

International Nuclear Information System (INIS)

Kieft, Thomas; Amy, Penny S.; Phillips, Fred M.

1998-01-01

This project was conducted as part of the Department of Energy's Deep Subsurface Science Program. It was part of a larger effort to determine the origins of subsurface microorganisms. Two hypotheses have been suggested for the origins of subsurface microorganisms: (1) microorganisms were deposited at the time of (or shortly after) geologic deposition of rocks and sediments (the in situ survival hypothesis), and (2) microorganisms have been transported from surface environments to subsurface rocks and sediments since the time of geologic deposition (transport hypothesis). These two hypotheses are not mutually exclusive. Depending on the geological setting, either one or both of these hypotheses may best explain microbial origins. Our project focused on the in situ survival hypothesis. We tested the hypothesis that microorganisms (individuals populations and communities) can survive long-term sequestration within subsurface sediments. Other objectives were to identify geologic conditions that favor long-term survival, identify physiological traits of microorganisms that favor long-term survival, and determine which groups of microorganisms are most likely to survive long-term sequestration in subsurface sediments. We tested this hypothesis using a combination of pure culture techniques in laboratory microcosms under controlled conditions and field experiments with buried subsurface sediments

Science To Support DOE Site Cleanup: The Pacific Northwest National Laboratory Environmental Management Science Program Awards; FINAL

International Nuclear Information System (INIS)

Bredt, Paul R; Brockman, Fred J; Grate, Jay W; Hess, Nancy J; Meyer, Philip D; Murray, Christopher J; Pfund, David M; Su, Yali; Thornton, Edward C; Weber, William J; Zachara, John M

2001-01-01

Pacific Northwest National Laboratory (PNNL) was awarded ten Environmental Management Science Program (EMSP) research grants in fiscal year 1996, six in fiscal year 1997, nine in fiscal year 1998, seven in fiscal year 1999, and five in fiscal year 2000. All of the fiscal year 1996 award projects have published final reports. The 1997 and 1998 award projects have been completed or are nearing completion. Final reports for these awards will be published, so their annual updates will not be included in this document. This section summarizes how each of the 1999 and 2000 grants address significant U.S. Department of Energy (DOE) cleanup issues, including those at the Hanford Site. The technical progress made to date in each of these research projects is addressed in more detail in the individual progress reports contained in this document. The 1999 and 2000 EMSP awards at PNNL are focused primarily in two areas: Tank Waste Remediation, and Soil and Groundwater Cleanup

Life sciences payload definition and integration study. Volume 2: Requirements, design, and planning studies for the carry-on laboratories. [for Spacelab

Science.gov (United States)

1974-01-01

The task phase concerned with the requirements, design, and planning studies for the carry-on laboratory (COL) began with a definition of biomedical research areas and candidate research equipment, and then went on to develop conceptual layouts for COL which were each evaluated in order to arrive at a final conceptual design. Each step in this design/evaluation process concerned itself with man/systems integration research and hardware, and life support and protective systems research and equipment selection. COL integration studies were also conducted and include attention to electrical power and data management requirements, operational considerations, and shuttle/Spacelab interface specifications. A COL program schedule was compiled, and a cost analysis was finalized which takes into account work breakdown, annual funding, and cost reduction guidelines.

Underground coal gasification: Development of theory, laboratory experimentation, interpretation, and correlation with the Hanna field tests: Final report

Energy Technology Data Exchange (ETDEWEB)

Gunn, R.D.; Krantz, W.B.

1987-03-01

The following report is a description of a 7 year effort to develop a theoretical understanding of the underground coal gasification process. The approach used is one of the mathematical model development from known chemical and principles, simplification of the models to isolate important effects, and through validation of models to isolate important effects, and through validation of models with laboratory experiments and field test data. Chapter I contains only introductory material. Chapter II describes the development of two models for reverse combustion: a combustion model and a linearized model for combustion front instability. Both models are required for realistic field predictions. Chapter III contains a discussion of a successful forward gasification model. Chapter IV discusses the spalling-enhanced-drying model is applicable to prediction of cavity growth and subsidence. Chapter VI decribes the correct use of energy and material balances for the analysis of UCG field test data. Chapter VII shows how laboratory experiments were used to validate the models for reverse combustion and forward gasification. It is also shown that laboratory combustion tube experiments can be used to simulate gas compositions expected from field tests. Finally, Chapter VII presents results from a comprehensive economic analysis of UCG involving 1296 separate cases. 37 refs., 49 figs., 12 tabs.

Ripeness sensor development. Final report of a Phase 2 study

Energy Technology Data Exchange (ETDEWEB)

Stroshine, R.

1995-08-01

This is a final report for the Phase II study entitled ``Ripeness Sensor Development.`` The overall objective of the study was the development of a prototype device capable of testing whole fruits for sugar content. Although ripeness and sugar content are not synonymous, they are closely related. Furthermore, the consumer`s acceptance of or preference for fruits is strongly influenced by sugar content. Therefore, the device was called a ripeness sensor. The principle behind the measurement is proton magnetic resonance ({sup 1}H-MR). For several decades, chemists, pharmacists and other scientists have been using {sup 1}H-MR to investigate chemical structure and composition. More recently, the technique has been used in laboratories of the food industry for quality control. This effort represents one of the first attempts to adapt {sup 1}H-MR to use in a commercial facility. 28 refs., 36 figs., 7 tabs.

Coloured solar collectors. Phase II : from laboratory samples to collector prototypes. Final report

Energy Technology Data Exchange (ETDEWEB)

Schueler, A; Roecker, Ch; Chambrier, E de; Munari Probst, M

2007-07-01

This illustrated final report for the Swiss Federal Office of Energy (SFOE) deals with the second phase of a project concerning the architectural integration of glazed solar collectors into the facades of buildings for heat production. The factors that limit the integration of photovoltaic panels in facades are discussed. The authors state that, for a convincing demonstration, sufficiently large samples and high quality levels are needed. The sol-gel deposition of the multi-layered coatings on A4-sized glass panes demonstrated in the laboratory by EPFL-LESO are discussed. The coatings produced exhibit a coloured reflection in combination with a high solar transmittance, a homogenous appearance, and are free of visible defects. Film hardening by UV exposure is discussed: This should result in the speeding up of the sol-gel process and thus save energy, thereby significantly reducing costs. Collaboration with industry is discussed in which full-scale glass panes are to be coated with novel multiple layers. The novel glazing is to be integrated into first prototype collectors. The manufacturing and test processes for the prototypes manufactured are discussed in detail.

Laboratory Study of High Temperature Corrosion in Straw-fired Power Plants

DEFF Research Database (Denmark)

Montgomery, Melanie; Maahn, Ernst emanuel

1997-01-01

The components contributing to corrosion, HCl(g)SO2(g), KCl and K2SO4 were studied in the laboratory for Sandvik 8LR30 and Sanicro 28. The influence of HCl and SO2 was investigated at 600C material temperature and 600/800C flue gas temperature at time intervals up to 300 hours. The influence of ash...... deposits in air was examined at 525C-700C. Finally exposures were undertaken combining the aforementioned aggressive gas environment with the ash deposits. Thus the corrosion potential of individual components were evaluated and also whether they had a synergistic, antagonistic or additive effect on one...... another to influence the overall corrosion rate....

Aespoe Hard Rock Laboratory. Final report of the first stage of the tracer retention understanding experiments

International Nuclear Information System (INIS)

Winberg, A.; Andersson, Peter; Hermanson, Jan; Byegaard, Johan

2000-03-01

The first stage of the Tracer Retention Understanding Experiments (TRUE) was performed as a SKB funded project. The overall objectives of TRUE are to develop the understanding of radionuclide migration and retention in fractured rock, to evaluate the realism in applied model concepts, and to assess whether the necessary input data to the models can be collected from site characterisation. Further, to evaluate the usefulness and feasibility of different model approaches, and finally to provide in situ data on radionuclide migration and retention. The strive for address with multiple approaches is facilitated through a close collaboration with the Aespoe Task Force on Modelling of Groundwater Flow and Transport of Solutes. The TRUE programme is a staged programme which addresses various scales from laboratory ( 22 Na + 47 Ca 2+ ≅ 85 Sr 2+ 86 Rb + ≅ 133 Ba 2+ The field tracer tests, using essentially the same cocktail of sorbing tracers as in the laboratory, were found to show the same relative sorbtivity as seen in the laboratory. A test using 137 Cs showed that after termination of the test, some 63% of the injected activity remained sorbed in the rock. The interpretation of the in situ tests with sorbing tracers was performed using the LaSAR approach, developed as a part of the TRUE project. In this approach the studied flow path is viewed as a part of an open fracture. Key processes are spatially variable advection and mass transfer. The evaluation shows that laboratory diffusion data are not representative for in situ conditions, and that a close fit between field and modelled breakthrough is obtained only when a parameter group which includes diffusion is enhanced with a factor varying between 32-50 for all tracers and experiments (except for Cs) and 137 for Cs. Our interpretation is that the enhancement is mainly due to higher diffusivity/porosity and higher sorption in the part of the altered rim zone of the feature which is accessible over the time scales

Final Report - Phase II - Biogeochemistry of Uranium Under Reducing and Re-oxidizing Conditions: An Integrated Laboratory and Field Study

Energy Technology Data Exchange (ETDEWEB)

Peyton, Brent; Sani, Rajesh

2006-09-28

Our understanding of subsurface microbiology is hindered by the inaccessibility of this environment, particularly when the hydrogeologic medium is contaminated with toxic substances. Past research in our labs indicated that the composition of the growth medium (e.g., bicarbonate complexation of U(VI)) and the underlying mineral phase (e.g., hematite) significantly affects the rate and extent of U(VI) reduction and immobilization through a variety of effects. Our research was aimed at elucidating those effects to a much greater extent, while exploring the potential for U(IV) reoxidation and subsequent re-mobilization, which also appears to depend on the mineral phases present in the system. The project reported on here was an extension ($20,575) of the prior (much larger) project. This report is focused only on the work completed during the extension period. Further information on the larger impacts of our research, including 28 publications, can be found in the final report for the following projects: 1) Biogeochemistry of Uranium Under Reducing and Re-oxidizing Conditions: An Integrated Laboratory and Field Study Grant # DE-FG03-01ER63270, and 2) Acceptable Endpoints for Metals and Radionuclides: Quantifying the Stability of Uranium and Lead Immobilized Under Sulfate Reducing Conditions Grant # DE-FG03-98ER62630/A001 In this Phase II project, the toxic effects of uranium(VI) were studied using Desulfovibrio desulfuricans G20 in a medium containing bicarbonate or 1, 4-piperazinediethane sulfonic acid disodium salt monohydrate (PIPES) buffer (each at 30 mM, pH 7). The toxicity of uranium(VI) was dependent on the medium buffer and was observed in terms of longer lag times and in some cases, no measurable growth. The minimum inhibiting concentration (MIC) was 140 M U(VI) in PIPES buffered medium. This is 36 times lower than previously reported for D. desulfuricans. These results suggest that U(VI) toxicity and the detoxification mechanisms of G20 depend greatly on the

Study of CSR Effects in the Jefferson Laboratory FEL Driver

Energy Technology Data Exchange (ETDEWEB)

Hall, C. C. [Colorado State U.; Biedron, S. [Colorado State U.; Burleson, Theodore A. [Colorado State U.; Milton, Stephen V. [Colorado State U.; Morin, Auralee L. [Colorado State U.; Benson, Stephen V. [JLAB; Douglas, David R. [JLAB; Evtushenko, Pavel E. [JLAB; Hannon, Fay E. [JLAB; Li, Rui [JLAB; Tennant, Christopher D. [JLAB; Zhang, Shukui [JLAB; Carlsten, Bruce E. [LANL; Lewellen, John W. [LANL

2013-08-01

In a recent experiment conducted on the Jefferson Laboratory IR FEL driver the effects of Coherent Synchrotron Radiation (CSR) on beam quality were studied. The primary goal of this work was to explore CSR output and effect on the beam with variation of the bunch compression in the IR chicane. This experiment also provides a valuable opportunity to benchmark existing CSR models in a system that may not be fully represented by a 1-D CSR model. Here we present results from this experiment and compare to initial simulations of CSR in the magnetic compression chicane of the machine. Finally, we touch upon the possibility for CSR induced microbunching gain in the magnetic compression chicane, and show that parameters in the machine are such that it should be thoroughly damped.

Brookhaven National Laboratory, Upton, New York final environmental impact statement

International Nuclear Information System (INIS)

Liverman, J.L.

1977-07-01

Generally, data used for the statement were those which had been accumulated through the calendar year 1973. Since 1973, Environmental Monitoring Reports have been published for calendar years 1974 and 1975. A review of these more recent documents reveals that the data contained therein lead to no significant change in the conclusions drawn in this Environmental Impact Statement. Past Laboratory operations were considered only insofar as they contribute to continuing environmental impacts. Environmental effects were considered solely with respect to off-site consequences, the only exception being those cases where on-site effects have had or will have an impact on the long-term productivity of the Laboratory site

Case Studies in Sustainability Used in an Introductory Laboratory Course to Enhance Laboratory Instruction

Science.gov (United States)

Luster-Teasley, Stephanie; Hargrove-Leak, Sirena; Gibson, Willietta; Leak, Roland

2017-01-01

This educational research seeks to develop novel laboratory modules by using Case Studies in the Science Teaching method to introduce sustainability and environmental engineering laboratory concepts to 21st century learners. The increased interest in "going green" has led to a surge in the number of engineering students studying…

Leaching of wood ash - Laboratory and field studies; Lakning av vedaska - Laboratorie- och faeltstudier

Energy Technology Data Exchange (ETDEWEB)

Larsson, Per-Erik

2012-02-15

High forest production leads to diminishing amounts of base cations and micro nutrients in forest soils. This is due to uptake in, and harvest of, the trees. Losses can be compensated for by spreading stabilized wood ash on the forest ground, which means recycling of base cations and micro nutrients. Chemical composition of wood ash can easily be described by standard methods in the laboratory. However, this does not include the process of leaching in nature, such as which components and leaching rate for different compounds. During field conditions several factors are added, which are not available in the laboratory. After almost 10 years in the forest soils there still remains large quantities of the original product. Only 10-30 % of the wood ash products and 5 % of the lime product has been leached. In the laboratory study the leached amount was slightly larger, at the most 35 % for wood ash and 20 % for lime. Both studies indicate long time for weathering of the products in forest soils. Slower leaching rate from pellets of wood ash compared to leaching rate from crushed wood ash in the laboratory study is not verified by the field study. This indicates limited possibilities to control rates of leaching in the environment

Medicare program; revisions to payment policies under the physician fee schedule, clinical laboratory fee schedule & other revisions to Part B for CY 2014. Final rule with comment period.

Science.gov (United States)

2013-12-10

This major final rule with comment period addresses changes to the physician fee schedule, clinical laboratory fee schedule, and other Medicare Part B payment policies to ensure that our payment systems are updated to reflect changes in medical practice and the relative value of services. This final rule with comment period also includes a discussion in the Supplementary Information regarding various programs. (See the Table of Contents for a listing of the specific issues addressed in the final rule with comment period.)

Evaluation of the analytic performance of laboratories: inter-laboratorial study of the spectroscopy of atomic absorption

International Nuclear Information System (INIS)

Wong Wong, S. M.

1996-01-01

The author made an inter-laboratorial study, with the participation of 18 national laboratories, that have spectrophotometer of atomic absorption. To evaluate the methods of analysis of lead, sodium, potasium, calcium, magnesium, zinc, copper, manganese, and iron, in the ambit of mg/l. The samples, distributed in four rounds to the laboratories, were prepared from primary patterns, deionized and distilled water. The study evaluated the homogeneity and stability, and verified its concentration, using as a reference method, the spectrometry method of Inductively Coupled Plasma emission (1CP). To obtain the characteristics of analytic performance, it applied the norm ASTM E 691. To evaluated the analytic performance, it used harmonized protocol of the International Union of Pure and applied chemistry (IUPAC). The study obtained the 29% of the laboratories had a satisfactory analytic performance, 9% had a questionable performance and 62% made an unsatisfactory analytic performance, according to the IUPAC norm. The results of the values of the characteristic performance method, show that there is no intercomparability between the laboratories, which is attributed to the different methodologies of analysis. (S. Grainger)

Radiation carcinogenesis, laboratory studies

International Nuclear Information System (INIS)

Shellabarger, C.J.

1974-01-01

Laboratory studies on radioinduced carcinogenesis are reviewed. Some topics discussed are: radioinduced neoplasia in relation to life shortening; dose-response relationships; induction of skin tumors in rats by alpha particles and electrons; effects of hormones on tumor response; effects of low LET radiations delivered at low dose-rates; effects of fractionated neutron radiation; interaction of RBE and dose rate effects; and estimates of risks for humans from animal data. (U.S.)

Laboratory studies and model simulations of sorbent material behavior for an in-situ passive treatment barrier

International Nuclear Information System (INIS)

Aloysius, D.; Fuhrmann, M.

1995-01-01

This paper presents a study combining laboratory experiments and model simulations in support of the design and construction of a passive treatment barrier (or filter wall) for retarding the migration of Sr-90 within a water-bearing surficial sand and gravel layer. Preliminary evaluation was used to select materials for column testing. A one-dimensional finite-difference model was used to simulate the laboratory column results and extrapolation of the calibrated model was then used to assess barrier performance over extended time frames with respect to Sr-90 breakthrough and loading on the filter media. The final results of the study showed that 20 by 50 mesh clinoptilolite will attenuate Sr-90 with a maximum life expentancy of approximately 10 years. This time period is based on allowable limits of Sr-90 activity on the filter media and is also a function of site-specific conditions

Radionuclide contaminated soil: Laboratory study and economic analysis of soil washing. Final report

International Nuclear Information System (INIS)

Fuhrmann, M.; Zhou, H.; Patel, B.; Bowerman, B.; Brower, J.

1996-01-01

The objective of the work discussed in this report is to determine if soil washing is a feasible method to remediate contaminated soils from the Hazardous Waste Management Facility (HWMF) at Brookhaven National Laboratory (BNL). The contaminants are predominantly Cs-137 and Sr-90. The authors have assumed that the target activity for Cs-137 is 50 pCi/g and that remediation is required for soils having greater activities. Cs-137 is the limiting contaminant because it is present in much greater quantities than Sr-90. This work was done in three parts, in which they: estimated the volume of contaminated soil as a function of Cs-137 content, determined if simple removal of the fine grained fraction of the soil (the material that is less than 0.063 mm) would effectively reduce the activity of the remaining soil to levels below the 50 pCi/g target, assessed the effectiveness of chemical and mechanical (as well as combinations of the two) methods of soil decontamination. From this analysis the authors were then able to develop a cost estimate for soil washing and for a baseline against which soil washing was compared

Setting priorities for action plans at Los Alamos National Laboratory. Final report

Energy Technology Data Exchange (ETDEWEB)

Miller, A.C.

1992-09-30

This report summarizes work done by Applied Decision Analysis (ADA) for Los Alamos National Laboratory (LANL) under Subcontract Number 9-XQ2-Y3837-1 with the University of California. The purpose of this work was to develop a method of setting priorities for environmental, safety, and health (ES&H) deficiencies at Los Alamos. The deficiencies were identified by a DOE Tiger Team that visited LANL in the fall of 1991, and by self assessments done by the Laboratory. ADA did the work described here between October 1991 and the end of September 1992. The ADA staff working on this project became part of a Risk Management Team in the Laboratory`s Integration and Coordination Office (ICO). During the project, the Risk Management Team produced a variety of documents describing aspects of the action-plan prioritization system. Some of those documents are attached to this report. Rather than attempt to duplicate their contents, this report provides a guide to those documents, and references them whenever appropriate.

Laboratory Directed Research and Development Annual Report - Fiscal Year 2000; FINAL

International Nuclear Information System (INIS)

Fisher, Darrell R; Hughes, Pamela J; Pearson, Erik W

2001-01-01

The projects described in this report represent the Laboratory's investment in its future and are vital to maintaining the ability to develop creative solutions for the scientific and technical challenges faced by DOE and the nation. In accordance with DOE guidelines, the report provides, (a) a director's statement, (b) an overview of the laboratory's LDRD program, including PNNL's management process and a self-assessment of the program, (c) a five-year project funding table, and (d) project summaries for each LDRD project

Final definition and preliminary design study for the initial atmospheric cloud physics laboratory, a spacelab mission payload

Science.gov (United States)

1976-01-01

The Atmospheric Cloud Physics Laboratory (ACPL) task flow is shown. Current progress is identified. The requirements generated in task 1 have been used to formulate an initial ACPL baseline design concept. ACPL design/functional features are illustrated. A timetable is presented of the routines for ACPL integration with the spacelab system.

[Quality Management and Quality Specifications of Laboratory Tests in Clinical Studies--Challenges in Pre-Analytical Processes in Clinical Laboratories].

Science.gov (United States)

Ishibashi, Midori

2015-01-01

The cost, speed, and quality are the three important factors recently indicated by the Ministry of Health, Labour and Welfare (MHLW) for the purpose of accelerating clinical studies. Based on this background, the importance of laboratory tests is increasing, especially in the evaluation of clinical study participants' entry and safety, and drug efficacy. To assure the quality of laboratory tests, providing high-quality laboratory tests is mandatory. For providing adequate quality assurance in laboratory tests, quality control in the three fields of pre-analytical, analytical, and post-analytical processes is extremely important. There are, however, no detailed written requirements concerning specimen collection, handling, preparation, storage, and shipping. Most laboratory tests for clinical studies are performed onsite in a local laboratory; however, a part of laboratory tests is done in offsite central laboratories after specimen shipping. As factors affecting laboratory tests, individual and inter-individual variations are well-known. Besides these factors, standardizing the factors of specimen collection, handling, preparation, storage, and shipping, may improve and maintain the high quality of clinical studies in general. Furthermore, the analytical method, units, and reference interval are also important factors. It is concluded that, to overcome the problems derived from pre-analytical processes, it is necessary to standardize specimen handling in a broad sense.

Linking Aerosol Optical Properties Between Laboratory, Field, and Model Studies

Science.gov (United States)

Murphy, S. M.; Pokhrel, R. P.; Foster, K. A.; Brown, H.; Liu, X.

2017-12-01

The optical properties of aerosol emissions from biomass burning have a significant impact on the Earth's radiative balance. Based on measurements made during the Fourth Fire Lab in Missoula Experiment, our group published a series of parameterizations that related optical properties (single scattering albedo and absorption due to brown carbon at multiple wavelengths) to the elemental to total carbon ratio of aerosols emitted from biomass burning. In this presentation, the ability of these parameterizations to simulate the optical properties of ambient aerosol is assessed using observations collected in 2017 from our mobile laboratory chasing wildfires in the Western United States. The ambient data includes measurements of multi-wavelength absorption, scattering, and extinction, size distribution, chemical composition, and volatility. In addition to testing the laboratory parameterizations, this combination of measurements allows us to assess the ability of core-shell Mie Theory to replicate observations and to assess the impact of brown carbon and mixing state on optical properties. Finally, both laboratory and ambient data are compared to the optical properties generated by a prominent climate model (Community Earth System Model (CESM) coupled with the Community Atmosphere Model (CAM 5)). The discrepancies between lab observations, ambient observations and model output will be discussed.

Treatment and final disposal of nuclear waste. Aespoe hard rock laboratory

International Nuclear Information System (INIS)

1992-09-01

The scientific investigations within SBK's research programme are a part of the work of designing a deep repository and identifying and investigating a suitable site. A balanced appraisal of the facts, requirements and assessments presented in connection with the preparation of R and D-programme 86 led to the proposal to construct an underground research laboratory. This proposal was presented in the aforementioned research programme and was very positively recived by the reviewing bodies. In the autumn of 1986, SKB initiated the field work for the siting of an underground laboratory, the Aespoe hard rock laboratory, in the Simpevarp area in the municipality of Oskarshamn. At the end of 1988, SKB arrived at a decision in principle to site the facility on southern Aespoe about 2 km north of the Oskarshamn nuclear power station. After regulatory review, SKB ordered the excavation of the access tunnel to the Aespoe hard rock laboratory to commence in the autumn of 1990. In conjunction with the tunneling work, which has now (September 1992) reached a depth of more than 200 m, a large number of investigations have been carried out. This background report to SKB's RD and D-programme 92 is based on the previous and 89 /2/. The report provides a general background and presents goals, projects results obtained to date and future work. Compared to the previous background reports, more space is devoted here to experiment planning and the future demonstration programme. (au)

The Aespoe Hard Rock Laboratory: Final evaluation of the hydrogeochemical pre-investigations in relation to existing geologic and hydraulic conditions

International Nuclear Information System (INIS)

Smellie, J.; Laaksoharju, M.

1992-11-01

The Swedish Nuclear Fuel and Management Company (SKB) is currently excavating the access tunnel to an underground experimental laboratory, the Aespoe Hard Rock Laboratory, planned to be located some 500 m below the island of Aespoe which is located in the Simpevarp area, southeast Sweden. The construction of an underground laboratory forms part of the overall SKB strategy to test, not only the construction techniques for deep excavation, but also the various methods and protocols required to obtain a three-dimensional model of the geology and groundwater flow and chemistry, within a fractured crystalline bedrock similar to that envisaged for the final disposal of spent fuel. Aespoe was chosen because it geologically represents a variety of typical crystalline bedrock environments. The hydrogeochemical activities described and interpreted in this report form part of the initial pre-investigation phase (from the surface to around 1000 metres depth) aimed at siting the laboratory, describing the natural hydrogeological and hydrogeochemical conditions in the bedrock and predicting the changes that will occur during excavation and construction of the laboratory. Hydrogeochemical interpretation has therefore been closely integrated with the hydrogeological investigations and other disciplines of major influence, in particular, bedrock geology and geochemistry and fracture mineralogy and chemistry. A large section of this report has been devoted to the detailed investigation of each individual zone hydraulically selected, tested and sampled for hydrogeochemical characterization. The data have been used to describe the chemistry and origin of the Aespoe groundwaters, models have been developed to illustrate groundwater mixing and standard geochemical modelling approaches have been employed to understand rock/water interaction processes. An attempt has been made to integrate the hydrogeochemical information with known geological and hydrogeological parameters to construct a

Laboratory testing in hyperthyroidism.

Science.gov (United States)

Grebe, Stefan K G; Kahaly, George J

2012-09-01

The clinical diagnosis of hypo- or hyperthyroidism is difficult (full text available online: http://education.amjmed.com/pp1/272). Clinical symptoms and signs are often non-specific, and there is incomplete correlation between structural and functional thyroid gland changes. Laboratory testing is therefore indispensible in establishing the diagnosis of thyrotoxicosis. Similar considerations apply to treatment monitoring. Laboratory testing also plays a crucial role in establishing the most likely cause for a patient's hyperthyroidism. Finally, during pregnancy, when isotopic scanning is relatively contraindicated and ultrasound is more difficult to interpret, laboratory testing becomes even more important. Copyright © 2012. Published by Elsevier Inc.

[External quality assessment in clinical biochemistry laboratories: pilot study in 11 laboratories of Lomé (Togo)].

Science.gov (United States)

Kouassi, Kafui; Fétéké, Lochina; Assignon, Selom; Dorkenoo, Ameyo; Napo-Koura, Gado

2015-01-01

This study aims to evaluate the performance of a few biochemistry analysis and make recommendations to the place of the stakeholders. It is a cross-sectional study conducted between the October 1(st), 2012 and the July 31, 2013 bearing on the results of 5 common examinations of clinical biochemistry, provided by 11 laboratories volunteers opening in the public and private sectors. These laboratories have analysed during the 3 cycles, 2 levels (medium and high) of serum concentration of urea, glucose, creatinine and serum aminotransferases. The performance of laboratories have been determined from the acceptable limits corresponding to the limits of total errors, defined by the French Society of Clinical Biology (SFBC). A system of internal quality control is implemented by all laboratories and 45% of them participated in international programs of external quality assessment (EQA). The rate of acceptable results for the entire study was of 69%. There was a significant difference (plaboratories engaged in a quality approach and the group with default implementation of the quality approach. Also a significant difference was observed between the laboratories of the central level and those of the peripheral level of our health system (plaboratories remains relatively unsatisfactory. It is important that the Ministry of Health put in place a national program of EQA with mandatory participation.

Integrated management system best practices in radioecological laboratories

International Nuclear Information System (INIS)

Carvalho, Claudia Aparecida Zerbinatti de

2010-01-01

The research aims to study the best practices to support a conceptual proposal for IMS - Integrated Management System (quality, environment, safety and health) applicable to Radioecology laboratories. The research design is organized into the following steps: in a first step, it was developed the bibliographic and documentary research in IMS, survey and study of standards (QMS ISO 9000 (2005), ISO 9001 (2008), ISO 9004 (2000), EMS ISO 14001 (2004) and OHSMS OHSAS 18001 (2007) and OHSAS 18002 (2008)), identification and characterization of processes in Radioecology Laboratories and study of best practices methodology and benchmarking; in the second stage of the research it was developed a case study (qualitative research, with questionnaires via e-mail and interviews, when possible), preceded by a survey and selection of international and national radioecology laboratories and then these laboratories were contacted and some of them agreed to participate in this research; in the third stage of the research it was built the framework of best practices that showed results that could support the conceptual proposal for the IMS Radioecology Laboratory; the fourth and final stage of research consisted in the construction of the proposed conceptual framework of SGI for Radioecology Laboratory, being then achieved the initial objective of the research. (author)

Managing laboratory automation.

Science.gov (United States)

Saboe, T J

1995-01-01

This paper discusses the process of managing automated systems through their life cycles within the quality-control (QC) laboratory environment. The focus is on the process of directing and managing the evolving automation of a laboratory; system examples are given. The author shows how both task and data systems have evolved, and how they interrelate. A BIG picture, or continuum view, is presented and some of the reasons for success or failure of the various examples cited are explored. Finally, some comments on future automation need are discussed.

LABORATORY SCALE STEAM INJECTION TREATABILITY STUDIES

Science.gov (United States)

Laboratory scale steam injection treatability studies were first developed at The University of California-Berkeley. A comparable testing facility has been developed at USEPA's Robert S. Kerr Environmental Research Center. Experience has already shown that many volatile organic...

VIRTUS. Virtual underground laboratory in rock salt; VIRTUS. Virtuelles Untertagelabor im Steinsalz

Energy Technology Data Exchange (ETDEWEB)

Wieczorek, Klaus [Gesellschaft fuer Anlagen- und Reaktorsicherheit mbH (GRS), Koeln (Germany); Behlau, Joachim; Heemann, Ulrich [Bundesanstalt fuer Geowissenschaften und Rohstoffe, Hannover (Germany); Masik, Steffen; Raab, Michael [Fraunhofer-Institut fuer Fabrikbetrieb und -Automatisierung (IFF), Magdeburg (Germany); Mueller, Christian; Simo, Eric Kuate [DBE Technology GmbH, Peine (Germany)

2014-12-15

Germany does not have an underground laboratory to study the behavior of geological formations for the use as final repository for radioactive high-level wastes. VIRTUS was developed to have an adequate tool to study the complex and safety relevant processes in geological structures for a fast and effective planning and testing of final repository design. The three-dimensional visualization of the numerical simulations results will help n the scientists and the interested public to understand the process flows in a final repository.

Life sciences payload definition and integration study. Volume 1: Executive summary. [carry-on laboratory for Spacelab

Science.gov (United States)

1974-01-01

The definition and integration tasks involved in the development of design concepts for a carry-on laboratory (COL), to be compatible with Spacelab operations, were divided into the following study areas: (1) identification of research and equipment requirements of the COL; (2) development of a number of conceptual layouts for COL based on the defined research of final conceptual designs; and (4) development of COL planning information for definition of COL/Spacelab interface data, cost data, and program cost schedules, including design drawings of a selected COL to permit fabrication of a functional breadboard.

Women's Experiences in the Engineering Laboratory in Japan

Science.gov (United States)

Hosaka, Masako

2014-01-01

This qualitative study aims to examine Japanese women undergraduate engineering students' experiences of interacting with departmental peers of the same year in the laboratory setting by using interview data of 32 final-year students at two modestly selective national universities in Japan. Expectation state theory that explains unequal…

Decommissioning of the MTR-605 process water building at the Idaho National Engineering Laboratory. Final report

International Nuclear Information System (INIS)

Browder, J.H.; Wills, E.L.

1985-01-01

Decontamination and decommissioning (D and D) of the unused radioactively contaminated portions of the MTR-605 building at the Test Reactor Area of the Idaho National Engineering Laboratory has been completed; this final report describes the D and D project. The building is a two-story concrete structure that was used to house piping systems to channel and control coolant water flow for the Materials Testing Reactor (MTR), a 40 MW (thermal) light water test reactor that was operated from 1952 until 1970 and then deactivated. D and D project objectives were to reduce potential environmental and radioactive contamination hazards to levels as low a reasonably achievable. Primary tasks of the D and D project were: to remove contaminated piping (about 400 linear ft of 36- and 30-in.-dia stainless steel pipe) and valves from the primary coolant pipe tunnels, to remove a primary coolant pump and piping, and to remove the three 8-ft-dia by 25-ft-long evaporators from the building second floor

State of laboratory manual instruction in California community college introductory (non-majors) biology laboratory instruction

Science.gov (United States)

Priest, Michelle

College students must complete a life science course prior to graduation for a bachelor's degree. Generally, the course has lecture and laboratory components. It is in the laboratory where there are exceptional opportunities for exploration, challenge and application of the material learned. Optimally, this would utilize the best of inquiry based approaches. Most community colleges are using a home-grown or self written laboratory manual for the direction of work in the laboratory period. Little was known about the motivation, development and adaptation of use. It was also not known about the future of the laboratory manuals in light of the recent learning reform in California Community Colleges, Student Learning Outcomes. Extensive interviews were conducted with laboratory manual authors to determine the motivation, process of development, who was involved and learning framework used in the creation of the manuals. It was further asked of manual authors their ideas about the future of the manual, the development of staff and faculty and finally, the role Student Learning Outcomes would play in the manual. Science faculty currently teaching the non-majors biology laboratories for at least two semesters were surveyed on-line about actual practice of the manual, assessment, manual flexibility, faculty training and incorporation of Student Learning Outcomes. Finally, an evaluation of the laboratory manual was done using an established Laboratory Task Analysis Instrument. Laboratory manuals were evaluated on a variety of categories to determine the level of inquiry instruction done by students in the laboratory section. The results were that the development of homegrown laboratory manuals was done by community colleges in the Los Angeles and Orange Counties in an effort to minimize the cost of the manual to the students, to utilize all the exercises in a particular lab and to effectively utilize the materials already owned by the department. Further, schools wanted to

A Chance to Get Ahead: Proficiency Examinations for Clerical Laboratory Personnel. Final Report.

Science.gov (United States)

Linehan, Jean D.

Four Proficiency Examinations for Clinical Laboratory Personnel were developed in Clinical Chemistry, Microbiology, Hematology, and Blood Banking. Purpose of project was to enable competent military laboratory technicians who lack credentials to demonstrate their job-related skills and knowledge for civilian positions, and also to help civilians…

Design study of underground facility of the Underground Research Laboratory

International Nuclear Information System (INIS)

Hibiya, Keisuke; Akiyoshi, Kenji; Ishizuka, Mineo; Anezaki, Susumu

1998-03-01

Geoscientific research program to study deep geological environment has been performed by Power Reactor and Nuclear Fuel Development Corporation (PNC). This research is supported by 'Long-Term Program for Research, Development and Utilization of Nuclear Energy'. An Underground Research Laboratory is planned to be constructed at Shoma-sama Hora in the research area belonging to PNC. A wide range of geoscientific research and development activities which have been previously studied at the Tono Area is planned in the laboratory. The Underground Research Laboratory is consisted of Surface Laboratory and Underground Research Facility located from the surface down to depth between several hundreds and 1,000 meters. Based on the results of design study in last year, the design study performed in this year is to investigate the followings in advance of studies for basic design and practical design: concept, design procedure, design flow and total layout. As a study for the concept of the underground facility, items required for the facility are investigated and factors to design the primary form of the underground facility are extracted. Continuously, design methods for the vault and the underground facility are summarized. Furthermore, design procedures of the extracted factors are summarized and total layout is studied considering the results to be obtained from the laboratory. (author)

Identification of laboratory techniques to optimize Superpave HMA surface friction characteristics : final report, April 2010.

Science.gov (United States)

2010-04-15

Wet pavement friction is known to be one of the most important roadway safety parameters. In this : research, frictional properties of flexible (asphalt) pavements were investigated. : As a part of this study, a laboratory device to polish asphalt sp...

Plug-In Hybrid Electric Vehicle Market Introduction Study: Final Report

Energy Technology Data Exchange (ETDEWEB)

Sikes, Karen [Sentech, Inc.; Gross, Thomas [Sentech, Inc.; Lin, Zhenhong [ORNL; Sullivan, John [University of Michigan Transportation Research Institute; Cleary, Timothy [Sentech, Inc.; Ward, Jake [U.S. Department of Energy

2010-02-01

Oak Ridge National Laboratory (ORNL), Sentech, Inc., Pacific Northwest National Laboratory (PNNL)/University of Michigan Transportation Research Institute (UMTRI), and the U.S. Department of Energy (DOE) have conducted a Plug-in Hybrid Electric Vehicle (PHEV) Market Introduction Study to identify and assess the effect of potential policies, regulations, and temporary incentives as key enablers for a successful market debut. The timeframe over which market-stimulating incentives would be implemented - and the timeframe over which they would be phased out - are suggested. Possible sources of revenue to help fund these mechanisms are also presented. In addition, pinch points likely to emerge during market growth are identified and proposed solutions presented. Finally, modeling results from ORNL's Market Acceptance of Advanced Automotive Technologies (MA3T) Model and UMTRI's Virtual AutoMotive MarketPlace (VAMMP) Model were used to quantify the expected effectiveness of the proposed policies and to recommend a consensus strategy aimed at transitioning what begins as a niche industry into a thriving and sustainable market by 2030. The primary objective of the PHEV Market Introduction Study is to identify the most effective means for accelerating the commercialization of PHEVs in order to support national energy and economic goals. Ideally, these mechanisms would maximize PHEV sales while minimizing federal expenditures. To develop a robust market acceleration program, incentives and policies must be examined in light of: (1) clarity and transparency of the market signals they send to the consumer; (2) expenditures and resources needed to support them; (3) expected impacts on the market for PHEVs; (4) incentives that are compatible and/or supportive of each other; (5) complexity of institutional and regulatory coordination needed; and (6) sources of funding.

Personal epistemological growth in a college chemistry laboratory environment

Science.gov (United States)

Keen-Rocha, Linda S.

The nature of this study was to explore changes in beliefs and lay a foundation for focusing on more specific features of reasoning related to personal epistemological and NOS beliefs in light of specific science laboratory instructional pedagogical practices (e.g., pre- and post-laboratory activities, laboratory work) for future research. This research employed a mixed methodology, foregrounding qualitative data. The total population consisted of 56 students enrolled in several sections of a general chemistry laboratory course, with the qualitative analysis focusing on the in-depth interviews. A quantitative NOS and epistemological beliefs measure was administered pre- and post-instruction. These measures were triangulated with pre-post interviews to assure the rigor of the descriptions generated. Although little quantitative change in NOS was observed from the pre-post NSKS assessment a more noticeable qualitative change was reflected by the participants during their final interviews. The NSKS results: the mean gain scores for the overall score and all dimensions, except for amoral were found to be significant at p ≤ .05. However there was a more moderate change in the populations' broader epistemological beliefs (EBAPS) which was supported during the final interviews. The EBAPS results: the mean gain scores for the overall score and all dimensions, except for the source of ability to learn were found to be significant at p ≤ .05. The participants' identified the laboratory work as the most effective instructional feature followed by the post-laboratory activities. The pre-laboratory was identified as being the least effective feature. The participants suggested the laboratory work offered real-life experiences, group discussions, and teamwork which added understanding and meaning to their learning. The post-laboratory was viewed as necessary in tying all the information together and being able to see the bigger picture. What one cannot infer at this point is

Laboratory Oxidation Stability Study on B10 Biodiesel Blends

Energy Technology Data Exchange (ETDEWEB)

Engelen, B. [and others

2013-11-15

A laboratory oxidation stability study has been completed jointly by CONCAWE and DGMK on three biodiesel blends containing 10% v/v (B10) Fatty Acid Methyl Ester (FAME). The results of the study are compared to measurements from an in-vehicle storage stability study on similar B10 diesel fuels that had been conducted previously in a Joint Industry Study. This laboratory study monitored the oxidation stability of the three B10 blends during six weeks of laboratory storage under ambient (25C) and elevated temperature (43C) conditions. Various test methods were used to monitor oxidation stability changes in the B10 diesel fuel blends including electrical conductivity, viscosity, Rancimat oxidation stability (EN 15751), PetroOxy oxidation stability (EN 16091), acid number (EN 14104), Delta Total Acid Number (Delta TAN), and peroxide number (ISO 3960). Elemental analyses by ICP were also completed on the FAME and B10 blends at the start and end of the laboratory study. The concentrations of dissolved metals were very low in all cases except for silicon which was found to be between about 600-700 ppb in the B10 blends. A limited study was also conducted on one neat FAME sample (B100) to investigate the effect of air/oxygen exposure on the rate of decrease in oxidation stability.

Terrain And Laboratory Conductivity Studies Of Flood Plains Of ...

African Journals Online (AJOL)

A shallow electromagnetic study (electrical conductivity and magnetic susceptibility measurements) and laboratory conductivity sampling of the flood plains of Oluwatuyi/Oshinle area of Akure have been undertaken. This is with the aim of correlating the terrain conductivity mapping with laboratory measurements to establish ...

Supplement to final report for ''Theoretical studies in tokamaks''

International Nuclear Information System (INIS)

McBride, J.B.

1992-07-01

In a previous report we summarized the results obtained for Task I of Contract Number AC03-88ER53270 for the two-year period of performance of the work supported by the contract. That report constituted the final report for Task 1. Since then, the contract was extended and the funding for Task I was incremented with $35K of new funds. The purpose for incrementing the contract was to begin a collaboration with the PBX-M group at Princeton Plasma Physics Laboratory (PPPL) in the area of ion Bernstein wave (IBW) effects in the PBX-M experiment. This report summarizes the initial results of that collaboration obtained under the incremental continuation funding. In the intervening period, experimental and theoretical program directions changed so that no further funds were committed to Task 1

Compact acoustic levitation device for studies in fluid dynamics and material science in the laboratory and microgravity

Science.gov (United States)

Trinh, E. H.

1985-01-01

An ultrasonic levitation device operable in both ordinary ground-based as well as in potential space-borne laboratories is described together with its various applications in the fields of fluid dynamics, material science, and light scattering. Some of the phenomena which can be studied by this instrument include surface waves on freely suspended liquids, the variations of the surface tension with temperature and contamination, the deep undercooling of materials with the temperature variations of their density and viscosity, and finally some of the optical diffraction properties of transparent substances.

Laboratory Information Management System (LIMS): A case study

Science.gov (United States)

Crandall, Karen S.; Auping, Judith V.; Megargle, Robert G.

1987-01-01

In the late 70's, a refurbishment of the analytical laboratories serving the Materials Division at NASA Lewis Research Center was undertaken. As part of the modernization efforts, a Laboratory Information Management System (LIMS) was to be included. Preliminary studies indicated a custom-designed system as the best choice in order to satisfy all of the requirements. A scaled down version of the original design has been in operation since 1984. The LIMS, a combination of computer hardware, provides the chemical characterization laboratory with an information data base, a report generator, a user interface, and networking capabilities. This paper is an account of the processes involved in designing and implementing that LIMS.

A Three-Year Feedback Study of a Remote Laboratory Used in Control Engineering Studies

Science.gov (United States)

Chevalier, Amélie; Copot, Cosmin; Ionescu, Clara; De Keyser, Robin

2017-01-01

This paper discusses the results of a feedback study for a remote laboratory used in the education of control engineering students. The goal is to show the effectiveness of the remote laboratory on examination results. To provide an overview, the two applications of the remote laboratory are addressed: 1) the Stewart platform, and 2) the quadruple…

Design of laboratory radiotracer studies in marine radioecology

International Nuclear Information System (INIS)

Schulte, E.H.

1997-01-01

A condensed description of methods used in laboratory radiotracer studies in marine radioecology is presented showing also the difficulties which may be encountered in order to obtain realistic and comparable information on the general behaviour of radionuclides in marine organisms. Practical guidance on the choice of the biological material and how to setup laboratory experiments and to control properly important experimental conditions are given. Key parameters like concentration factors and biological half-lives are defined and the theoretical estimation and practical determination of input, uptake, accumulation and loss of radionuclides in marine biota are formulated by the aid of mathematical equations. Examples of uptake and loss curves obtained in the laboratory are shown. The importance of some environmental factors (temperature, food, growth) on uptake and loss of radionuclides are demonstrated. Comparison of experimental and field data of concentration factors is reported to show the difficulty in extrapolating from laboratory experiments to nature. (author)

Phase B-final definition and preliminary design study for the initial Atmospheric Cloud Physics Laboratory (ACPL). A spacelab mission payload

Science.gov (United States)

1976-01-01

Progress in the development of the Atmospheric Cloud Physics Laboratory is outlined. The fluid subsystem, aerosol generator, expansion chamber, optical system, control systems, and software are included.

The laboratories of geological studies

International Nuclear Information System (INIS)

1994-01-01

This educational document comprises 4 booklets in a folder devoted to the presentation of the ANDRA's activities in geological research laboratories. The first booklet gives a presentation of the missions of the ANDRA (the French agency for the management of radioactive wastes) in the management of long life radioactive wastes. The second booklet describes the approach of waste disposal facilities implantation. The third booklet gives a brief presentation of the scientific program concerning the underground geologic laboratories. The last booklet is a compilation of questions and answers about long-life radioactive wastes, the research and works carried out in geologic laboratories, the public information and the local socio-economic impact, and the storage of radioactive wastes in deep geological formations. (J.S.)

Effect of ceramic thickness and cement shade on the final shade after bonding using the 3D master system: a laboratory study.

Science.gov (United States)

Montero, Javier; Gómez-Polo, Cristina

2016-06-01

The final color of a ceramic restoration is influenced by both the ceramic thickness and the cement shade. This study aims to evaluate the color stability according to the 3D Master System of e.max ceramic discs after bonding with different shades of luting agents. A total of 120 e.max.Press 2M1 HT ceramic discs (60 discs of 1-mm thick and 60 discs of 0.5 mm thick) and three different values of Variolink Veneer cement were used (-3, 0, +3) for the cementation process. An Easyshade compact device was used to measure color shade tabs, according to the 3D Master System, on the discs both before and after the cementation protocols. Bivariate and multivariate analyses were carried out with the spss v.21. After bonding with the different luting agents, only 30% remained as 2M1: specifically, 22% of the thinner discs and 37.3% of the thicker discs. In general, the effect of bonding increased the value and the chroma of the shade to a significant extent. Regression analyses revealed that the most significant predictor for all color parameters was cement shade, the thinner disc group bonded with -3 cement being the most unstable subgroup. According to the 3D Master System, the shade of the luting agent was the main predictor of the final color. However, the final color seems to be somewhat unpredictable, at least according to the modulating factors evaluated in the present study.

Laboratory Animal Workers’ Attitudes and Perceptions Concerning Occupational Risk and Injury

OpenAIRE

Steelman, Eric D; Alexander, Jeffrey L

2016-01-01

Little is known regarding the risk perceptions and attitudes of laboratory animal care workers toward biologic safety. The purpose of this descriptive study was to assess the attitudes and perceptions of laboratory animal workers toward occupational and injury risk. Subscribers to the CompMed and TechLink listservs (n = 4808) were surveyed electronically, and 5.3% responded; data from 215 respondents were included in the final analysis. Primary variables of interest included AALAS certificati...

Final Report - Phase II - Biogeochemistry of Uranium Under Reducing and Re-oxidizing Conditions: An Integrated Laboratory and Field Study ($20,575 extension)

International Nuclear Information System (INIS)

Brent Peyton; Rajesh Sani

2006-01-01

Our understanding of subsurface microbiology is hindered by the inaccessibility of this environment, particularly when the hydrogeologic medium is contaminated with toxic substances. Past research in our labs indicated that the composition of the growth medium (e.g., bicarbonate complexation of U(VI)) and the underlying mineral phase (e.g., hematite) significantly affects the rate and extent of U(VI) reduction and immobilization through a variety of effects. Our research was aimed at elucidating those effects to a much greater extent, while exploring the potential for U(IV) reoxidation and subsequent re-mobilization, which also appears to depend on the mineral phases present in the system. The project reported on here was an extension ($20,575) of the prior (much larger) project. This report is focused only on the work completed during the extension period. Further information on the larger impacts of our research, including 28 publications, can be found in the final report for the following projects: (1) Biogeochemistry of Uranium Under Reducing and Re-oxidizing Conditions: An Integrated Laboratory and Field Study Grant DE-FG03-01ER63270, and (2) Acceptable Endpoints for Metals and Radionuclides: Quantifying the Stability of Uranium and Lead Immobilized Under Sulfate Reducing Conditions Grant DE-FG03-98ER62630/A001 In this Phase II project, the toxic effects of uranium(VI) were studied using Desulfovibrio desulfuricans G20 in a medium containing bicarbonate or 1, 4-piperazinediethane sulfonic acid disodium salt monohydrate (PIPES) buffer (each at 30 mM, pH 7). The toxicity of uranium(VI) was dependent on the medium buffer and was observed in terms of longer lag times and in some cases, no measurable growth. The minimum inhibiting concentration (MIC) was 140 (micro)M U(VI) in PIPES buffered medium. This is 36 times lower than previously reported for D. desulfuricans. These results suggest that U(VI) toxicity and the detoxification mechanisms of G20 depend greatly

Unlocking the Laboratory: Autonomous Wireless Sensor Authentication in Practice

Science.gov (United States)

Huggard, Meriel; McGoldrick, Ciaran

2013-01-01

Purpose: The purpose of this study is to evaluate a practical laboratory task where final year undergraduate students design, implement and validate an inferred security wireless sensor access system. Design/methodology/approach: The quality of the learning and technical environment was evaluated from a number of perspectives using a mixed methods…

Final Report Bald and Golden Eagle Territory Surveys for the Lawrence Livermore National Laboratory

Energy Technology Data Exchange (ETDEWEB)

Fratanduono, M. L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2014-11-25

Garcia and Associates (GANDA) was contracted by the Lawrence Livermore National Laboratory (LLNL) to conduct surveys for bald eagles (Haliaeetus leucocephalus) and golden eagles (Aquila chrysaetos) at Site 300 and in the surrounding area out to 10-miles. The survey effort was intended to document the boundaries of eagle territories by careful observation of eagle behavior from selected viewing locations throughout the study area.

Environmental Safety and Health Analytical Laboratory, Pantex Plant, Amarillo, Texas. Final Environmental Assessment

International Nuclear Information System (INIS)

1995-06-01

The US Department of Energy (DOE) has prepared an Environmental Assessment (EA) of the construction and operation of an Environmental Safety and Health (ES ampersand H) Analytical Laboratory and subsequent demolition of the existing Analytical Chemistry Laboratory building at Pantex Plant near Amarillo, Texas. In accordance with the Council on Environmental Quality requirements contained in 40 CFR 1500--1508.9, the Environmental Assessment examined the environmental impacts of the Proposed Action and discussed potential alternatives. Based on the analysis of impacts in the EA, conducting the proposed action, construction of an analytical laboratory and demolition of the existing facility, would not significantly effect the quality of the human environment within the meaning of the National Environmental Policy Act of 1969 (NEPA) and the Council on Environmental Quality regulations in 40 CFR 1508.18 and 1508.27

Small scale model and underground laboratory study of engineered barrier thermal behaviour

International Nuclear Information System (INIS)

Dardaine, M.; Beziat, A.; Gatabin, C.; Lefevre, I.; Plas, F.; Fontan, N.; Moyne, C.

1991-01-01

This is the final report of the contract CCE FI1W/0061, which had the objective of studying the thermal behaviour of the engineered barrier having the selected French clay Fo-Ca (natural calcic smectite) as its major constituent. After being installed this barrier was subjected simultaneously to the heat flux dissipated by the container and to a possible rehydration by contact with the host medium. It consists of three parts. The first part is devoted to R and D studies concerning detectors suitable for the point measurement of the water concentration. Among the techniques that can be envisaged, capacitor methods, which are very temperature sensitive, would require a great deal of effort to be satisfactory. On the other hand, the water concentration can, in principle, be derived from the measurement of the thermal conductivity in the transient regime. Although the carrying out of this measurement is somewhat critical, it can give good results under certain conditions. The second part reports experiments carried out in the laboratory concerning both the study of heat transfer during the so-called dry phase of the disposal (without any water being supplied externally) and the study of the phenomenon of fissuration. Finally, the third part describes the in situ experiment BACCHUS, carried out in the underground test facility at Mol (Belgium), in collaboration with the CEN/SCK. In the course of the five months of the thermal phase of this experiment a large variation in the amplitude of the temperature gradients was recorded, which may be explained, on one hand, by the convergence of the medium and, on the other hand, by a much more rapid rehydration than that predicted

Comparison of basic laboratory test results with more sophisticated laboratory and in-situ tests methods on soils in southeastern Wisconsin : final report, March 21, 2009.

Science.gov (United States)

2009-03-21

This study investigates all of the generated soils data in an attempt to use the more 'routine' laboratory tests to determine geotechnical design parameters (such as phiangle, cohesion, wet unit weight, unconfined compression, consolidation character...

Laboratory modeling, field study, and numerical simulation of bioremediation of petroleum contaminants

International Nuclear Information System (INIS)

Livingston, R.J.; Islam, M.R.

1999-01-01

Historical methods of cleaning up petroleum hydrocarbons from the vadose zone, the capillary zone, and the aquifers are not technically true cleanup technologies but rather transfer techniques. In addition, environmental engineers are realizing that the standard remediation techniques are not entirely effective in removing the hazardous material in a reasonable time frame. Long-chain hydrocarbons such as kerosene, diesel, and waste oil are particularly difficult to remediate using conventional techniques. The use of bioremediation as an alternative remediation technology is fast becoming the technique of choice among many environmental professionals. This method offers substantial benefits not found in other remediation processes. Bioremediation is very cost effective, nondestructive, relatively uncomplicated in implementing, requires non specialized equipment, and can be extremely effective in removing recalcitrant petroleum hydrocarbons. This study researched the availability of viable microbial populations in the arid climate in South Dakota. Exponential growth of the bacteria and the ability of bacteria to degrade long-chain hydrocarbons indicated that healthy populations do exist and could be used to mineralize organic hydrocarbons. Experimental results indicated that bioremediation can be effectively enhanced in landfills as well as in the subsurface using a supply of harmless nutrients. The biodegradation rate can be further enhanced with the use of edible surfactant that helped disperse the petroleum products. Also, the use of hydrogen peroxide enhanced the oxygen availability and increased the degradation rate. Interestingly, the bacterial growth rate is found to be high in difficult-to-biodegrade contaminants, such as waste oil. A numerical simulation program was also developed that describes the bacterial growth in the subsurface along with the reduction in substrate (contamination). Results from this program were found to be consistent with laboratory

Actinide partitioning-transmutation program final report. III. Transmutation studies

International Nuclear Information System (INIS)

Wachter, J.W.; Croff, A.G.

1980-07-01

Transmutation of the long-lived nuclides contained in fuel cycle wastes has been suggested as a means of reducing the long-term toxicity of the wastes. A comprehensive program to evaluate the feasibility and incentives for recovering the actinides from wastes (partitioning) and transmuting them to short-lived or stable nuclides has been in progress for 3 years under the direction of Oak Ridge National Laboratory (ORNL). This report constitutes the final assessment of transmutation in support of this program. Included are (1) a summary of recent transmutation literature, (2) a generic evaluation of actinide transmutation in thermal, fast, and other transmutation devices, (3) a preliminary evaluation of 99 Tc and 129 I transmutation, and (4) a characterization of a pressurized-water-reactor fuel cycle with and without provisions for actinide recovery and transmutation for use in other parts of the ORNL program. The principal conclusion of the report is that actinide transmutation is feasible in both thermal and fast reactors, subject to demonstrating satisfactory fuel performance, with relatively little impact on the reactor. It would also appear that additional transmutation studies are unwarranted until a firm decision to proceed with actinide transmutation has been made by the responsible authorities

Methodological and reporting quality in laboratory studies of human eating behavior

NARCIS (Netherlands)

Robinson, E.; Bevelander, K.E.; Field, M.; Jones, A.

2018-01-01

The methodological quality and reporting practices of laboratory studies of human eating behavior determine the validity and replicability of nutrition science. The aim of this research was to examine basic methodology and reporting practices in recent representative laboratory studies of human

Commercialization of Los Alamos National Laboratory technologies via small businesses. Final report

Energy Technology Data Exchange (ETDEWEB)

Brice, R.; Cartron, D.; Rhyne, T.; Schulze, M.; Welty, L.

1997-06-01

Over the past decade, numerous companies have been formed to commercialize research results from leading U.S. academic and research institutions. Emerging small businesses in areas such as Silicon Valley, Boston`s Route 128 corridor, and North Carolina`s Research Triangle have been especially effective in moving promising technologies from the laboratory bench to the commercial marketplace--creating new jobs and economic expansion in the process. Unfortunately, many of the U.S. national laboratories have not been major participants in this technology/commercialization activity, a result of a wide variety of factors which, until recently, acted against successful commercialization. This {open_quotes}commercialization gap{close_quotes} exists partly due to a lack, within Los Alamos in particular and the DOE in general, of in-depth expertise and experience in such business areas as new business development, securities regulation, market research and the determination of commercial potential, the identification of entrepreneurial management, marketing and distribution, and venture capital sources. The immediate consequence of these factors is the disappointingly small number of start-up companies based on technologies from Los Alamos National Laboratory that have been attempted, the modest financial return Los Alamos has received from these start-ups, and the lack of significant national recognition that Los Alamos has received for creating and commercializing these technologies.

Mine-by experiment final design report

International Nuclear Information System (INIS)

Read, R.S.; Martin, C.D.

1991-12-01

The Underground Research Laboratory (URL) Mine-by Experiment is designed to provide information on rock mass response to excavation that will be used to assess important aspects of the design of a nuclear fuel waste disposal vault in a granitic pluton. The final experiment design is the result of a multidisciplinary approach, drawing on experience gained at other sites as well as the URL, and using both internal expertise and the external consultants. The final experiment design, including details on characterization, construction, instrumentation, and numerical modelling, is presented along with final design drawings

Laboratory Investigations of Stratospheric Halogen Chemistry

Science.gov (United States)

Wine, Paul H.; Nicovich, J. Michael; Stickel, Robert E.; Hynes, Anthony J.

1997-01-01

A final report for the NASA-supported project on laboratory investigations of stratospheric halogen chemistry is presented. In recent years, this project has focused on three areas of research: (1) kinetic, mechanistic, and thermochemical studies of reactions which produce weakly bound chemical species of atmospheric interest; (2) development of flash photolysis schemes for studying radical-radical reactions of stratospheric interest; and (3) photochemistry studies of interest for understanding stratospheric chemistry. The first section of this paper contains a discussion of work which has not yet been published. All subsequent chapters contain reprints of published papers that acknowledge support from this grant.

Laboratory Approaches to Studying Occupants

DEFF Research Database (Denmark)

Wagner, Andreas; Andersen, Rune; Zhang, Hui

2018-01-01

is high and a large number of physical, physiological, and psychological quantities can be monitored. This chapter gives an overview of various types of test facilities in the world and their main features in terms of experimental opportunities. It then presents typical technical equipment and sensor......Laboratories offer the possibility to study occupant behavior in a very detailed manner. A wide range of indoor environmental scenarios can be simulated under precisely controlled conditions, and human subjects can be selected based on pre-defined criteria. The degree of control over experiments...

Expanded studies of linear collider final focus systems at the Final Focus Test Beam

International Nuclear Information System (INIS)

Tenenbaum, P.G.

1995-12-01

In order to meet their luminosity goals, linear colliders operating in the center-of-mass energy range from 3,50 to 1,500 GeV will need to deliver beams which are as small as a few Manometers tall, with x:y aspect ratios as large as 100. The Final Focus Test Beam (FFTB) is a prototype for the final focus demanded by these colliders: its purpose is to provide demagnification equivalent to those in the future linear collider, which corresponds to a focused spot size in the FFTB of 1.7 microns (horizontal) by 60 manometers (vertical). In order to achieve the desired spot sizes, the FFTB beam optics must be tuned to eliminate aberrations and other errors, and to ensure that the optics conform to the desired final conditions and the measured initial conditions of the beam. Using a combination of incoming-beam diagnostics. beam-based local diagnostics, and global tuning algorithms, the FFTB beam size has been reduced to a stable final size of 1.7 microns by 70 manometers. In addition, the chromatic properties of the FFTB have been studied using two techniques and found to be acceptable. Descriptions of the hardware and techniques used in these studies are presented, along with results and suggestions for future research

Expanded studies of linear collider final focus systems at the Final Focus Test Beam

Energy Technology Data Exchange (ETDEWEB)

Tenenbaum, Peter Gregory [Stanford Univ., CA (United States)

1995-12-01

In order to meet their luminosity goals, linear colliders operating in the center-of-mass energy range from 3,50 to 1,500 GeV will need to deliver beams which are as small as a few Manometers tall, with x:y aspect ratios as large as 100. The Final Focus Test Beam (FFTB) is a prototype for the final focus demanded by these colliders: its purpose is to provide demagnification equivalent to those in the future linear collider, which corresponds to a focused spot size in the FFTB of 1.7 microns (horizontal) by 60 manometers (vertical). In order to achieve the desired spot sizes, the FFTB beam optics must be tuned to eliminate aberrations and other errors, and to ensure that the optics conform to the desired final conditions and the measured initial conditions of the beam. Using a combination of incoming-beam diagnostics. beam-based local diagnostics, and global tuning algorithms, the FFTB beam size has been reduced to a stable final size of 1.7 microns by 70 manometers. In addition, the chromatic properties of the FFTB have been studied using two techniques and found to be acceptable. Descriptions of the hardware and techniques used in these studies are presented, along with results and suggestions for future research.

Army agrees to new study of biowarfare laboratory.

Science.gov (United States)

Smith, R Jeffrey

1985-02-08

As a result of a lawsuit initiated by Washington activist Jeremy Rifkin and joined by the attorney general for the state of Utah, the U.S. Army has agreed to defer construction, pending a study of potential environmental hazards, of a new laboratory that was authorized by a small number of Congressmen under an unusual procedure in December 1984. The laboratory, intended for tests of highly infectious and lethal biological aerosols, has aroused controversy because of fears that the data gathered there might be used to develop offensive biological weapons.

Variability of creatinine measurements in clinical laboratories: results from the CRIC study.

Science.gov (United States)

Joffe, Marshall; Hsu, Chi-yuan; Feldman, Harold I; Weir, Matthew; Landis, J R; Hamm, L Lee

2010-01-01

Estimating equations using serum creatinine (SCr) are often used to assess glomerular filtration rate (GFR). Such creatinine (Cr)-based formulae may produce biased estimates of GFR when using Cr measurements that have not been calibrated to reference laboratories. In this paper, we sought to examine the degree of this variation in Cr assays in several laboratories associated with academic medical centers affiliated with the Chronic Renal Insufficiency Cohort (CRIC) Study; to consider how best to correct for this variation, and to quantify the impact of such corrections on eligibility for participation in CRIC. Variability of Cr is of particular concern in the conduct of CRIC, a large multicenter study of subjects with chronic renal disease, because eligibility for the study depends on Cr-based assessment of GFR. A library of 5 large volume plasma specimens from apheresis patients was assembled, representing levels of plasma Cr from 0.8 to 2.4 mg/dl. Samples from this library were used for measurement of Cr at each of the 14 CRIC laboratories repetitively over time. We used graphical displays and linear regression methods to examine the variability in Cr, and used linear regression to develop calibration equations. We also examined the impact of the various calibration equations on the proportion of subjects screened as potential participants who were actually eligible for the study. There was substantial variability in Cr assays across laboratories and over time. We developed calibration equations for each laboratory; these equations varied substantially among laboratories and somewhat over time in some laboratories. The laboratory site contributed the most to variability (51% of the variance unexplained by the specimen) and variation with time accounted for another 15%. In some laboratories, calibration equations resulted in differences in eligibility for CRIC of as much as 20%. The substantial variability in SCr assays across laboratories necessitates calibration

Kansas State University accelerator laboratory upgrade

International Nuclear Information System (INIS)

Richard, P.

1989-01-01

The J.R. Macdonald Laboratory is undergoing a major upgrade of its facilities and capabilities. The laboratory is dedicated to the study of ion-atom collisions using highly charged ions from accelerators and/or ion sources. The mainstay of the laboratory over the last two decades has been a 6 MV tandem accelerator. It has been used to produce one- to a few-MeV/u highly charged ions for studying high energy atomic collisions, and to produce recoil ions from ocllisions with projectile ions for studying low energy atomic collisions. In order to enhance the capabilities of studying atomic collisions in these two energy regimes, we are constructing a superconducting LINAC booster to the tandem, and a stand-alone CRYEBIS source. The project, which is funded by the US Department of Energy, began in May 1985 with a May 1989 completion schedule. The upgrade includes a building addition, funded by the State of Kansas, to house the new facilities. The LINAC consists of a time-superbunching module, followed by three large cryostat modules each containing four superconducting resonators, and followed by an energy-rebunching module. The resonators are the split-ring superconducting Nb type designed and constructed at Argonne National Laboratory, and are presently being tested at KSU. The CRYEBIS source, which consists of a 1 m long 5 T superconducting solenoid with a high degree of straightness, is in the final stages of assembly. We have in operation a new computer network for data acquisition and analysis. A progress report on the status of the upgrade is presented. (orig.)

Final Report on Pilot Studies / Final Report on Classroom Research with STEM and TESL Assessment

DEFF Research Database (Denmark)

Biel, Carmen; Wake, Jo Dugstad; Hesse, Friedrich

This Deliverable is the final report on pilot studies within the NEXT-TELL project (D6.7) and furthermore comprises the Deliverable on Classroom Research with STEM and TESL Assessment (D2.9) in order to avoid redundancies between those two Deliverables.......This Deliverable is the final report on pilot studies within the NEXT-TELL project (D6.7) and furthermore comprises the Deliverable on Classroom Research with STEM and TESL Assessment (D2.9) in order to avoid redundancies between those two Deliverables....

Fresh biological reference materials. Use in inter laboratory studies and as CRMs

International Nuclear Information System (INIS)

De Boer, J.

1999-01-01

Biological reference materials were prepared and packed in tins and glass jars to be used in inter laboratory studies on chlorobiphenyls and organochlorine pesticides, and trace metals, respectively. The materials were homogenised, sterilised and packed as wet tissue, which is unique for the purpose of inter laboratory studies and offers the advantage of studying the extraction and destruction steps of the analytical methods. In addition to their use in inter laboratory studies, some materials have been prepared or are being prepared as certified reference material for chlorobiphenyl analysis. (author)

Going GLP: Conducting Toxicology Studies in Compliance with Good Laboratory Practices.

Science.gov (United States)

Carroll, Erica Eggers

2016-01-01

Good laboratory practice standards are US federal regulations enacted as part of the Federal Insecticide, Fungicide, and Rodenticide Act (40 CFR Part 160), the Toxic Substance Control Act (40 CFR Part 792), and the Good Laboratory Practice for Nonclinical Laboratory Studies (21 CFR Part 58) to support protection of public health in the areas of pesticides, chemicals, and drug investigations in response to allegations of inaccurate data acquisition. Essentially, good laboratory practices (GLPs) are a system of management controls for nonclinical research studies involving animals to ensure the uniformity, consistency, reliability, reproducibility, quality, and integrity of data collected as part of chemical (including pharmaceuticals) tests, from in vitro through acute to chronic toxicity tests. The GLPs were established in the United States in 1978 as a result of the Industrial Bio-Test Laboratory scandal which led to congressional hearings and actions to prevent fraudulent data reporting and collection. Although the establishment of infrastructure for GLPs compliance is labor-intensive and time-consuming, achievement and maintenance of GLP compliance ensures the accuracy of the data collected from each study, which is critical for defending results, advancing science, and protecting human and animal health. This article describes how and why those in the US Army Medical Department responsible for protecting the public health of US Army and other military personnel made the policy decision to have its toxicology laboratory achieve complete compliance with GLP standards, the first such among US Army laboratories. The challenges faced and how they were overcome are detailed.

Utica Shale Energy and Environment Laboratory Final Scientific/Technical Report

Energy Technology Data Exchange (ETDEWEB)

Cole, David Robert [The Ohio State Univ., Columbus, OH (United States); Allen, Gerald Robert [The Ohio State Univ., Columbus, OH (United States)

2017-12-29

The Ohio State University (OSU) was awarded a contract on October 1, 2014, from the Department of Energy National Energy Technology Laboratory (DOE-NETL) to develop the Utica Shale Energy and Environment Laboratory (USEEL) in the Utica-Point Pleasant shale play of the Appalachian Basin. It was designed to be an environmental and technology development lab that would enable the academic, industry, government, and non-governmental organization (NGO) research communities to better understand unconventional oil and gas (UOG) engineering practices and technology to increase production and safety, and decrease environmental effects. Political and economic consequences necessitated changes in project site location and design, from the Ohio State Eastern Agricultural Research Station (EARS) and the Muskingum Watershed Conservancy District (MWCD) in east-central Ohio to a site located at an Energy Corporation of America (ECA) Marcellus drill pad in Greene County, Pennsylvania. Although the overall project progressed little beyond planning and administration before termination on September 18, 2017, significant research and MS or PhD investigations were completed or continue today. An experimental study design for site specific and regional baseline assessments was developed utilizing ecoregions, United States Geological Survey (USGS) Hydraulic Unit Code watersheds, and GIS technology and databases. This can be utilized to build a defensible and scalable management and research framework for UOG investigations that can be extrapolated for predictive and comparative analyses. The most commonly mentioned perceived risks of shale energy development identified in a socioeconomic analysis included impacts to the environment and water resources, traffic and road deterioration, and crime. Economic benefits, such as the windfall wealth to residents, job opportunities, and the demand for hotels and restaurants emerged, as the main positive impact to the community. Preliminary results

Norcal Prototype LNG Truck Fleet: Final Results

Energy Technology Data Exchange (ETDEWEB)

2004-07-01

U.S. DOE and National Renewable Energy Laboratory evaluated Norcal Waste Systems liquefied natural gas (LNG) waste transfer trucks. Trucks had prototype Cummins Westport ISXG engines. Report gives final evaluation results.

A Dual Case Study: Students' Perceptions, Self-Efficacy and Understanding of the Nature of Science in Varied Introductory Biology Laboratories

Science.gov (United States)

Quigley, Dena Beth Boans

Since World War II, science education has been at the forefront of curricular reforms. Although the philosophical approach to science education has changed numerous times, the importance of the laboratory has not waned. A laboratory is meant to allow students to encounter scientific concepts in a very real, hands-on way so that they are able to either recreate experiments that have given rise to scientific theories or to use science to understand a new idea. As the interactive portion of science courses, the laboratory should not only reinforce conceptual ideas, but help students to understand the process of science and interest them in learning more about science. However, most laboratories have fallen into a safe pattern having teachers and students follow a scientific recipe, removing the understanding of and interest in science for many participants. In this study, two non-traditional laboratories are evaluated and compared with a traditional laboratory in an effort to measure student satisfaction, self-efficacy, attitudes towards science, and finally their epistemology of the nature of science (NOS). Students in all populations were administered a survey at the beginning and the end of their spring 2016 laboratory, and the survey was a mixture of qualitative questions and quantitative instruments. Overall, students who participated in one of the non-traditional labs rated their satisfaction higher and used affirming supportive statements. They also had significant increases in self-efficacy from pre to post, while the students in the traditional laboratory had a significant decrease. The students in the traditional laboratory had significant changed in attitudes towards science, as did the students in one of the non-traditional laboratories. All students lacked a firm grasp of the tenets of NOS, although one laboratory that includes explicit discussions of NOS saw improvement in at least on tenet. Data for two non-major biology laboratory populations was

High-precision, whole-genome sequencing of laboratory strains facilitates genetic studies.

Directory of Open Access Journals (Sweden)

Anjana Srivatsan

2008-08-01

Full Text Available Whole-genome sequencing is a powerful technique for obtaining the reference sequence information of multiple organisms. Its use can be dramatically expanded to rapidly identify genomic variations, which can be linked with phenotypes to obtain biological insights. We explored these potential applications using the emerging next-generation sequencing platform Solexa Genome Analyzer, and the well-characterized model bacterium Bacillus subtilis. Combining sequencing with experimental verification, we first improved the accuracy of the published sequence of the B. subtilis reference strain 168, then obtained sequences of multiple related laboratory strains and different isolates of each strain. This provides a framework for comparing the divergence between different laboratory strains and between their individual isolates. We also demonstrated the power of Solexa sequencing by using its results to predict a defect in the citrate signal transduction pathway of a common laboratory strain, which we verified experimentally. Finally, we examined the molecular nature of spontaneously generated mutations that suppress the growth defect caused by deletion of the stringent response mediator relA. Using whole-genome sequencing, we rapidly mapped these suppressor mutations to two small homologs of relA. Interestingly, stable suppressor strains had mutations in both genes, with each mutation alone partially relieving the relA growth defect. This supports an intriguing three-locus interaction module that is not easily identifiable through traditional suppressor mapping. We conclude that whole-genome sequencing can drastically accelerate the identification of suppressor mutations and complex genetic interactions, and it can be applied as a standard tool to investigate the genetic traits of model organisms.

Semiconductor laser joint study program with Rome Laboratory

Science.gov (United States)

Schaff, William J.; Okeefe, Sean S.; Eastman, Lester F.

1994-09-01

A program to jointly study vertical-cavity surface emitting lasers (VCSEL) for high speed vertical optical interconnects (VOI) has been conducted under an ES&E between Rome Laboratory and Cornell University. Lasers were designed, grown, and fabricated at Cornell University. A VCSEL measurement laboratory has been designed, built, and utilized at Rome Laboratory. High quality VCSEL material was grown and characterized by fabricating conventional lateral cavity lasers that emitted at the design wavelength of 1.04 microns. The VCSEL's emit at 1.06 microns. Threshold currents of 16 mA at 4.8 volts were obtained for 30 microns diameter devices. Output powers of 5 mW were measured. This is 500 times higher power than from the light emitting diodes employed previously for vertical optical interconnects. A new form of compositional grading using a cosinusoidal function has been developed and is very successful for reducing diode series resistance for high speed interconnection applications. A flip-chip diamond package compatible with high speed operation of 16 VCSEL elements has been designed and characterized. A flip-chip device binding effort at Rome Laboratory was also designed and initiated. This report presents details of the one-year effort, including process recipes and results.

Malaria Laboratory Diagnostic Performance: Case studies of two ...

African Journals Online (AJOL)

Advantages of rapid diagnostic tests when compared with microscopy are simple to perform, fast, low ... The study was conducted to establish the performance of laboratory diagnosis of malaria in local Malawi .... Government of Malawi.

Innovative subsurface stabilization project -- Final Report

International Nuclear Information System (INIS)

Loomis, G.G.; Zdinak, A.P.; Bishop, C.W.

1996-11-01

This is a report of results of applying four innovative grouting materials and one commercially available material for creating monoliths out of buried waste sites using jet grouting. The four innovative materials included a proprietary water-based epoxy, an Idaho National Engineering Laboratory-developed two-component grout that resembles hematite when cured with soil, molten low-temperature paraffin, and a proprietary iron oxide cement-based grout called TECT. The commercial grout was Type-H high-sulfate-resistant cement. These materials were tested in specially designed cold test pits that simulate buried transuranic waste at the Idaho National Engineering Laboratory. In addition to the grouting studies, specially designed field-scale permeameters were constructed to perform full-scale controlled mass balance hydraulic conductivity studies. An ungrouted field-scale permeameter contained simulated buried waste and soil and was left ungrouted, and a second identical field-scale permeameter was grouted with commercial-grade Type-H cement. The field demonstrations were performed in an area referred to as the Cold Test Pit at the Idaho National Engineering Laboratory. The Cold Test Pit is adjacent to the laboratory's Radioactive Waste Management Complex. At the complex, 2 million ft 3 of transuranic waste is commingled with 6--8 million ft 3 of soil in shallow land burial, and improving the confinement of this waste is one of the options for final waste disposition. This report gives results of grouting, coring, hydraulic conductivity, and destructive examination of the grouted buried waste matrix

Decontamination and decommissioning of laboratory solutions enriched uranium (IR-01 b)

International Nuclear Information System (INIS)

Diaz Arocas, P. P.; Sama Colao, J.; Garcia Diaz, A.; Torre Rodriguez, J.; Martinez, A.; Argiles, E.; Garrido Delgado, C.

2010-01-01

Completed actions decontamination and decommissioning of the Laboratory of Enriched Uranium Solutions, attached to the Radioactivity lR-0l CIEMAT, was carried out final radiological control of the laboratory. From the documentation generated proceeded to request modification of the IR-01 installation by closing its laboratory IR-01 b.

Electric air filtration: theory, laboratory studies, hardware development, and field evaluations

International Nuclear Information System (INIS)

Bergman, W.; Biermann, A.; Kuhl, W.

1983-09-01

We summarize the results of a seven-year research project for the US Department of Energy (DOE) to develop electric air filters that extend the service life of high-efficiency particulate air (HEPA) filters used in the nuclear industry. This project was unique to Lawrence Livermore National Laboratory (LLNL), and it entailed comprehensive theory, laboratory studies, and hardware development. We present our work in three major areas: (1) theory of and instrumentation for filter test methods, (2) theoretical and laboratory studies of electric air filters, and (3) development and evaluation of eight experimental electric air filters

Summary report - development of laboratory tests and the stress- strain behaviour of Olkiluoto mica gneiss

International Nuclear Information System (INIS)

Hakala, M.; Heikkilae, E.

1997-05-01

This work summarizes the project aimed at developing and qualifying a suitable combination of laboratory tests to establish a statistically reliable stress-strain behaviour of the main rock types at Posiva Oy's detailed investigation sites for disposal of spent nuclear fuel. The work includes literature study of stress-strain behaviour of brittle rock, development and qualification of laboratory tests, suggested test procedures and interpretation methods and finally testing of Olkiluoto mica gneiss. The Olkiluoto study includes over 130 loading tests. Besides the commonly used laboratory tests, direct tensile tests, damage controlled tests and acoustic emission measurements were also carried out. (orig.) (54 refs.)

Acoustic testing and modeling: an advanced undergraduate laboratory.

Science.gov (United States)

Russell, Daniel A; Ludwigsen, Daniel O

2012-03-01

This paper describes an advanced laboratory course in acoustics, specifically targeted for students with an interest in engineering applications at a school with a strongly integrated industrial co-op program. The laboratory course is developed around a three-pronged approach to problem solving that combines and integrates theoretical models, computational models, and experimental data. The course is structured around modules that begin with fundamental concepts and build laboratory skills and expand the knowledge base toward a final project. Students keep a detailed laboratory notebook, write research papers in teams, and must pass laboratory certification exams. This paper describes the course layout and philosophy and shares personal experience from both faculty and student perspectives. © 2012 Acoustical Society of America

[Experimental nuclear physics]. Final report

International Nuclear Information System (INIS)

1991-04-01

This is the final report of the Nuclear Physics Laboratory of the University of Washington on work supported in part by US Department of Energy contract DE-AC06-81ER40048. It contains chapters on giant dipole resonances in excited nuclei, nucleus-nucleus reactions, astrophysics, polarization in nuclear reactions, fundamental symmetries and interactions, accelerator mass spectrometry (AMS), ultra-relativistic heavy ions, medium energy reactions, work by external users, instrumentation, accelerators and ion sources, and computer systems. An appendix lists Laboratory personnel, a Ph. D. degree granted in the 1990-1991 academic year, and publications. Refs., 41 figs., 7 tabs

[Experimental nuclear physics]. Final report

Energy Technology Data Exchange (ETDEWEB)

NONE

1991-04-01

This is the final report of the Nuclear Physics Laboratory of the University of Washington on work supported in part by US Department of Energy contract DE-AC06-81ER40048. It contains chapters on giant dipole resonances in excited nuclei, nucleus-nucleus reactions, astrophysics, polarization in nuclear reactions, fundamental symmetries and interactions, accelerator mass spectrometry (AMS), ultra-relativistic heavy ions, medium energy reactions, work by external users, instrumentation, accelerators and ion sources, and computer systems. An appendix lists Laboratory personnel, a Ph. D. degree granted in the 1990-1991 academic year, and publications. Refs., 41 figs., 7 tabs.

Description of the EDF research and development laboratory's radiographic picture processing system

International Nuclear Information System (INIS)

Brillault, B.

1985-01-01

A digital radiographic picture processing system has been developed at the EDF Research and Development Laboratory to be supplied to EDF radiography experts. We describe it in pointing out the difficulties of radiograph digitization but also the numerous processing possibilities. The final goal of the Laboratory work is to extract the information from industrial radiographs by digital means. Our study is divided into three parts: digitization by a microdensitometer; display, processing and quantization of flaws; and, digital storing. 5 refs

The performance assessment of undergraduate students in physics laboratory by using guided inquiry

Science.gov (United States)

Mubarok, H.; Lutfiyah, A.; Kholiq, A.; Suprapto, N.; Putri, N. P.

2018-03-01

The performance assessment of basic physics experiment among undergraduate physics students which includes three stages: pre-laboratory, conducting experiment and final report was explored in this study. The research used a descriptive quantitative approach by utilizing guidebook of basic physics experiment. The findings showed that (1) the performance of pre-laboratory rate among undergraduate physics students in good category (average score = 77.55), which includes the ability of undergraduate physics students’ theory before they were doing the experiment. (2) The performance of conducting experiment was in good category (average score = 78.33). (3) While the performance of final report was in moderate category (average score = 73.73), with the biggest weakness at how to analyse and to discuss the data and writing the abstract.

An educational laboratory virtual instrumentation suite assisted experiment for studying fundamentals of series resistance-inductance-capacitance circuit

Science.gov (United States)

Rana, K. P. S.; Kumar, Vineet; Mendiratta, Jatin

2017-11-01

One of the most elementary concepts in freshmen Electrical Engineering subject comprises the Resistance-Inductance-Capacitance (RLC) circuit fundamentals, that is, their time and frequency domain responses. For a beginner, generally, it is difficult to understand and appreciate the step and the frequency responses, particularly the resonance. This paper proposes a student-friendly teaching and learning approach by inculcating the multifaceted versatile software LabVIEWTM along with the educational laboratory virtual instrumentation suite hardware, for studying the RLC circuit time and frequency domain responses. The proposed approach has offered an interactive laboratory experiment where students can model circuits in simulation and hardware circuits on prototype board, and then compare their performances. The theoretical simulations and the obtained experimental data are found to be in very close agreement, thereby enhancing the conviction of students. Finally, the proposed methodology was also subjected to the assessment of learning outcomes based on student feedback, and an average score of 8.05 out of 10 with a standard deviation of 0.471 was received, indicating the overall satisfaction of the students.

Site-specific probabilistic seismic hazard analyses for the Idaho National Engineering Laboratory. Volume 1: Final report

International Nuclear Information System (INIS)

1996-05-01

This report describes and summarizes a probabilistic evaluation of ground motions for the Idaho National Engineering Laboratory (INEL). The purpose of this evaluation is to provide a basis for updating the seismic design criteria for the INEL. In this study, site-specific seismic hazard curves were developed for seven facility sites as prescribed by DOE Standards 1022-93 and 1023-96. These sites include the: Advanced Test Reactor (ATR); Argonne National Laboratory West (ANL); Idaho Chemical Processing Plant (ICPP or CPP); Power Burst Facility (PBF); Radioactive Waste Management Complex (RWMC); Naval Reactor Facility (NRF); and Test Area North (TAN). The results, probabilistic peak ground accelerations and uniform hazard spectra, contained in this report are not to be used for purposes of seismic design at INEL. A subsequent study will be performed to translate the results of this probabilistic seismic hazard analysis to site-specific seismic design values for the INEL as per the requirements of DOE Standard 1020-94. These site-specific seismic design values will be incorporated into the INEL Architectural and Engineering Standards

Cometabolic biotreatment of TCE-contaminated groundwater: Laboratory and bench-scale development studies

International Nuclear Information System (INIS)

Donaldson, T.L.; Jennings, H.L.; Lucero, A.J.; Strandberg, G.W.; Morris, M.I.; Palumbo, A.V.; Boerman, P.A.; Tyndall, R.L.

1992-01-01

The Oak Ridge National Laboratory is conducting a demonstration of two cometabolic technologies for biotreatment of groundwater contaminated with trichloroethylene (TCE) and other organics. Technologies based on methanotrophic (methane-utilizing) and toluene-degrading microorganisms will be compared side-by-side on the same groundwater stream. Laboratory and bench-scale bioreactor studies have been conducted to guide selection of microbial cultures and operating conditions for the field demonstration. This report presents the results of the laboratory and bench-scale studies for the methanotrophic system

Laboratory testing improves diagnosis and treatment outcomes in primary health care facilities

Directory of Open Access Journals (Sweden)

Jane Y. Carter

2012-10-01

Setting: Six rural health centres in Kenya. Design: Cross-sectional study to observe change in diagnosis and treatment made by clinical officers after laboratory testing in outpatients attending six rural health centres in Kenya. Subject: The diagnosis and treatment of 1134 patients attending outpatient services in six rural health centres were compared before and after basic laboratory testing. Essential clinical diagnostic equipment and laboratory tests were established at each health centre. Clinical officers and laboratory technicians received on-site refresher training in good diagnostic practices and laboratory procedures before the study began. Results: Laboratory tests were ordered on 704 (62.1% patients. Diagnosis and treatment were changed in 45% of tested patients who returned with laboratory results (21% of all patients attending the clinics. 166 (23.5% patients did not return to the clinician for a final diagnosis and management decision after laboratory testing. Blood slide examination for malaria parasites, wet preparations, urine microscopy and stool microscopy resulted in most changes to diagnosis. There was no significant change in drug costs after laboratory testing. The greatest changes in numbers of recorded diseases following laboratory testing was for intestinal worms (53% and malaria (21%. Conclusion: Effective use of basic laboratory tests at primary health care level significantly improves diagnosis and patient treatment. Use of laboratory testing can be readily incorporated into routine clinical practice. On-site refresher training is an effective means of improving the quality of patient care and communication between clinical and laboratory staff.

Multiyear Program Plan for the High Temperature Materials Laboratory; FINAL

International Nuclear Information System (INIS)

Arvid E. Pasto

2000-01-01

Recently, the U.S. Department of Energy's (DOE) Office of Heavy Vehicle Technologies (OHVT) prepared a Technology Roadmap describing the challenges facing development of higher fuel efficiency, less polluting sport utility vehicles, vans, and commercial trucks. Based on this roadmap, a multiyear program plan (MYPP) was also developed, in which approaches to solving the numerous challenges are enumerated. Additional planning has been performed by DOE and national laboratory staff, on approaches to solving the numerous challenges faced by heavy vehicle system improvements. Workshops and planning documents have been developed concerning advanced aerodynamics, frictional and other parasitic losses, and thermal management. Similarly, the Heavy Vehicle Propulsion Materials Program has developed its own multiyear program plan. The High Temperature Materials Laboratory, a major user facility sponsored by OHVT, has now developed its program plan, described herein. Information was gathered via participation in the development of OHVT's overall Technology Roadmap and MYPP, through personal contacts within the materials-user community, and from attendance at conferences and expositions. Major materials issues for the heavy vehicle industry currently center on trying to increase efficiency of (diesel) engines while at the same time reducing emissions (particularly NO(sub x) and particulates). These requirements dictate the use of increasingly stronger, higher-temperature capable and more corrosion-resistant materials of construction, as well as advanced catalysts, particulate traps, and other pollution-control devices. Exhaust gas recirculation (EGR) is a technique which will certainly be applied to diesel engines in the near future, and its use represents a formidable challenge, as will be described later. Energy-efficient, low cost materials processing methods and surface treatments to improve wear, fracture, and corrosion resistance are also required

Final report on progress of grant ''Few-nucleon systems in the laboratory, supernovae, and the cosmos''

International Nuclear Information System (INIS)

Phillips, Daniel R.

2006-01-01

In the past year I have pursued work in three different areas within the scope of my Department of Energy Outstanding Junior Investigator Award ''Few-nucleon systems in the laboratory, supernovae, and the cosmos''. The first, and main, focus of my research has been testing the usefulness of effective field theory (EFT) in describing Compton scattering for different targets: the proton, deuterium, and Helium-3. This has been where the bulk of my OJI effort has been dedicated in the past twelve months, and thus it is the longest section of this report. Secondly, I have been working on the application of EFT to the reaction π - d → γnn. Finally, I have also been involved in a non-EFT project: computing certain many-body effects which affect the neutrino cooling of neutron stars and supernovae. In what follows I first describe my work in each of these areas. I then discuss unexpended funds, and the students who have been supported under the aegis of this project, as well as listing publications, talks, etc. associated with this grant in 2004-05. This report describes progress made on research projects associated with my Department of Energy Outstanding Junior Investigator grant

Planetary Simulation Chambers bring Mars to laboratory studies

Energy Technology Data Exchange (ETDEWEB)

Mateo-Marti, E.

2016-07-01

Although space missions provide fundamental and unique knowledge for planetary exploration, they are always costly and extremely time-consuming. Due to the obvious technical and economical limitations of in-situ planetary exploration, laboratory simulations are among the most feasible research options for making advances in planetary exploration. Therefore, laboratory simulations of planetary environments are a necessary and complementary option to expensive space missions. Simulation chambers are economical, more versatile, and allow for a higher number of experiments than space missions. Laboratory-based facilities are able to mimic the conditions found in the atmospheres and on the surfaces of a majority of planetary objects. Number of relevant applications in Mars planetary exploration will be described in order to provide an understanding about the potential and flexibility of planetary simulation chambers systems: mainly, stability and presence of certain minerals on Mars surface; and microorganisms potential habitability under planetary environmental conditions would be studied. Therefore, simulation chambers will be a promising tools and necessary platform to design future planetary space mission and to validate in-situ measurements from orbital or rover observations. (Author)

Mapping the future of CIC Division, Los Alamos National Laboratory. Final report

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-01-01

This report summarizes three scenario-based strategic planning workshops run for the CIC Division of the Los Alamos National Laboratory during November and December, 1995. Each of the two-day meetings was facilitated by Northeast Consulting Resources, Inc. (NCRI) of Boston, MA. using the Future Mapping{reg_sign} methodology.

Cometabolic biotreatment of TCE-contaminated groundwater - Laboratory and bench-scale development studies

Energy Technology Data Exchange (ETDEWEB)

Donaldson, T L; Palumbo, A V; Boerman, P A; Jennings, H L; Lucero, A J; Tyndall, R L; Strandberg, G W; Morris, M I [Oak Ridge National Laboratory, Oak Ridge, TN (United States)

1992-07-01

The Oak Ridge National Laboratory is conducting a demonstration of two cometabolic technologies for biotreatment of groundwater contaminated with trichloroethylene (TCE) and other organics. Technologies based on methanotrophic (methane-utilizing) and toluene-degrading microorganisms will be compared side-by-side on the same groundwater stream. Laboratory and bench-scale bioreactor studies have been conducted to guide selection of microbial cultures and operating conditions for the field demonstration. This report presents the results of the laboratory and bench-scale studies for the methanotrophic system. (author)

Human risk relationships derived from epidemiology and laboratory studies

International Nuclear Information System (INIS)

Cuddihy, R.G.; Boecker, B.B.; Hahn, F.F.; McClellan, R.O.

1983-01-01

Proven techniques are needed for incorporating the results of laboratory toxicology studies into human risk assessments. Two sample calculations of lung cancer risk factors for inhaled radioactive particles and diesel engine exhaust are given here to illustrate a toxicology information matrix approach. This approach combines the results of epidemiology and laboratory animal studies of the substance or agent of principal concern, along with similar information on other surrogate substances. Beyond the estimates of lung cancer risk factors derived by using this approach, an additional advantage is gained by having estimates of uncertainty that can be obtained by incorporating all available toxicology information into the analysis. This approach is recommended for both risk assessment and in designing follow-on toxicology studies to improve preliminary assessments for new potentially harmful agents entering our environment

Final Environmental Impact Statement and Environmental Impact Report for continued operation of Lawrence Livermore National Laboratory and Sandia National Laboratories, Livermore

International Nuclear Information System (INIS)

1992-08-01

This Environmental Impact Statement/Environmental Impact Report (EIS/EIR) is prepared pursuant to the National Environmental Policy Act (NEPA) and the California Environmental Quality Act (CEQA). This document analyzes the potential environmental impacts of the proposed action: continued operation, including near-term (within 5 to 10 years) proposed projects, of Lawrence Livermore National Laboratory (LLNL) and Sandia National Laboratories, Livermore (SNL, Livermore). Additionally, this document analyzes a no action alternative involving continuing operations at FY 1992 funding levels without further growth, a modification of operations alternative to reduce adverse environmental impacts of operations or facilities, and a shutdown and decommissioning alternative of UC discontinuing its management of LLNL after the current contract expires on September 30, 1992. This document assesses the environmental impacts of the Laboratories' operations on air and water quality, geological and ecological systems, occupational and public health risks, prehistoric and historic resources, endangered species, floodplains and wetlands, socioeconomic resources, hazardous waste management, site contamination, and other environmental issues. The EIS/EIR is divided into five volumes and two companion reports. This volume contains copies of the written comments and transcripts of individual statements at the public hearing and the responses to them

Aespoe Hard Rock Laboratory. Final report of the first stage of the tracer retention understanding experiments

Energy Technology Data Exchange (ETDEWEB)

Winberg, A. [Conterra AB, Uppsala (Sweden); Andersson, Peter [Geosigma AB, Uppsala (Sweden); Hermanson, Jan [Golder Grundteknik, Solna (Sweden); Byegaard, Johan [Chalmers Univ. of Technology, Goeteborg (Sweden). Dept. of Nuclear Chemistry; Cvetkovic, V. [Royal Inst. of Tech., Stockholm (Sweden). Dept. of Water Resources Engineering; Birgersson, Lars [Kemakta Konsult AB, Stockholm (Sweden)

2000-03-15

The first stage of the Tracer Retention Understanding Experiments (TRUE) was performed as a SKB funded project. The overall objectives of TRUE are to develop the understanding of radionuclide migration and retention in fractured rock, to evaluate the realism in applied model concepts, and to assess whether the necessary input data to the models can be collected from site characterisation. Further, to evaluate the usefulness and feasibility of different model approaches, and finally to provide in situ data on radionuclide migration and retention. The strive for address with multiple approaches is facilitated through a close collaboration with the Aespoe Task Force on Modelling of Groundwater Flow and Transport of Solutes. The TRUE programme is a staged programme which addresses various scales from laboratory (< 0.5 m), detailed scale (< 10 m) and block scale (10-50 m). The First TRUE Stage was performed in the detailed scale with the specific objectives of providing data and conceptualising the investigated feature using conservative and sorbing tracers. Further, to improve methodologies for performing tracer tests, and to develop and test a methodology for obtaining pore volume/aperture data from epoxy resin injection, excavation and subsequent analyses. The experimental site is located at approximately 400 m depth in the northeastern part of the Aespoe Hard Rock Laboratory. The identification of conductive fractures and the target feature has benefited from the use of BIPS borehole TV imaging combined with detailed flow logging. The assessment of the conductive geometry has been further sustained by cross-hole pressure interference data. The investigated target feature (Feature A) is a reactivated mylonite which has later undergone brittle deformation. The feature is oriented northwest, along the principal horizontal stress orientation, and is a typical conductor for Aespoe conditions. Hydraulic characterisation shows that the feature is relatively well isolated

Laboratory Studies Of Circumstellar Carbonaceous Grain Formation

Science.gov (United States)

Contreras, Cesar; Sciamma-O'Brien, Ella; Salama, Farid

2014-06-01

The study of the formation processes of dust is essential to understand the budget of extraterrestrial organic molecules. Although dust with all its components plays an important role in the evolution of interstellar (IS) chemistry and in the formation of organic molecules, little is known on the formation processes of carbonaceous dust. We report the progress that was recently achieved in this domain using NASA Ames’ COSmIC facility (Contreras & Salama 2013, ApJS, 208, 6). PAHs are important chemical building blocks of IS dust. They are detected in IDPs and in meteoritic samples. Additionally, observational, laboratory, and theoretical studies have shown that PAHs are an important, ubiquitous component of the ISM. The formation of PAHs from smaller molecules has not been extensively studied. Therefore, we have performed laboratory experiments to study the dynamic processes of carbon grain formation, starting from the smallest hydrocarbon molecules into the formation of larger PAH and further into nanograins. Studies of IS dust analogs formed from a variety of PAH and hydrocarbon precursors as well as species that include the atoms O, N, and S, have recently been performed in our laboratory using the COSmIC facility to provide conditions that simulate IS and circumstellar environments. The species formed in the COSmiC chamber through a pulsed discharge nozzle plasma source are detected and characterized with a cavity ringdown spectrometer coupled to a time-of-flight mass spectrometer, thus providing both spectroscopic and ion mass information in-situ. Analysis of solid soot particles was also conducted using scanning electron microscopy at the UCSC/NASA Ames’ MACS facility. The SEM analysis of the deposition of soot from methane and acetylene precursors seeded in argon plasmas provide examples on the types of nanoparticles and micrograins that are produced in these gas mixtures under our experimental conditions. From these measurements, we derive information on

Wellness Center use at Los Alamos National Laboratory: a descriptive study

Energy Technology Data Exchange (ETDEWEB)

Wiggs, L.D.; Wilkinson, G.S.; Weber, C.

1985-10-01

This study describes employee participation during the first six months of the Los Alamos National Laboratory's corporate Wellness Program. We describe temporal patterns of use, preferred activities, frequency of use, and characteristics of employees participating in Wellness activities. Characteristics of Wellness participants are compared with characteristics of the Laboratory population. During this period the Wellness Center, a multi-use facility that houses Wellness Program activities, had 17,352 visits. Employees visiting the Wellness Center were typical of the Laboratory population in their racial and ethnic characteristics, but different in their sex and age composition. Wellness participants were younger and more likely to be female than the Laboratory population. 6 refs., 19 tabs.

Developing Medicare Competitive Bidding: A Study of Clinical Laboratories

Science.gov (United States)

Hoerger, Thomas J.; Meadow, Ann

1997-01-01

Competitive bidding to derive Medicare fees promises several advantages over administered fee systems. The authors show how incentives for cost savings, quality, and access can be incorporated into bidding schemes, and they report on a study of the clinical laboratory industry conducted in preparation for a bidding demonstration. The laboratory industry is marked by variable concentration across geographic markets and, among firms themselves, by social and economic heterogeneity. The authors conclude that these conditions can be accommodated by available bidding design options and by careful selection of bidding markets. PMID:10180003

Summary report - development of laboratory tests and the stress- strain behaviour of Olkiluoto mica gneiss

Energy Technology Data Exchange (ETDEWEB)

Hakala, M.; Heikkilae, E. [Helsinki Univ. of Technology, Espoo (Finland). Lab. of Rock Engineering

1997-05-01

This work summarizes the project aimed at developing and qualifying a suitable combination of laboratory tests to establish a statistically reliable stress-strain behaviour of the main rock types at Posiva Oy`s detailed investigation sites for disposal of spent nuclear fuel. The work includes literature study of stress-strain behaviour of brittle rock, development and qualification of laboratory tests, suggested test procedures and interpretation methods and finally testing of Olkiluoto mica gneiss. The Olkiluoto study includes over 130 loading tests. Besides the commonly used laboratory tests, direct tensile tests, damage controlled tests and acoustic emission measurements were also carried out. (orig.) (54 refs.).

Laboratory studies of imitation/field studies of tradition: towards a synthesis in animal social learning.

Science.gov (United States)

Galef, Bennett G

2015-03-01

Here I discuss: (1) historical precedents that have resulted in comparative psychologists accepting the two-action method as the "gold standard" in laboratory investigations of imitation learning, (2) evidence suggesting that the two-action procedure may not be adequate to answer questions concerning the role of imitation in the development of traditional behaviors of animals living in natural habitat, and (3) an alternative approach to the laboratory study of imitation that might increase the relevance of laboratory studies of imitation to the work of behavioral ecologists/primatologists interested in animal traditions and their relationship to human cumulative culture. This article is part of a Special Issue entitled: Tribute to Tom Zentall. Copyright © 2014 Elsevier B.V. All rights reserved.

Role of Skill Laboratory Training in Medical Education - Students Perspective

International Nuclear Information System (INIS)

Hashim, R.; Qamar, K.; Rehman, S.; Khan, M. A.

2016-01-01

Objective: To evaluate the perceptions of medical students regarding their training utilizing facilities provided in the skill laboratory of a public sector medical college. Study Design: Cross-sectional study. Place and Duration of Study: Army Medical College, Rawalpindi, from October to December 2014. Methodology: Students of final year MBBS who had underwent skill laboratory training were recruited through convenience purposive sampling. Students not exposed to skill laboratory training were excluded. Data collection tool was a questionnaire having 23 questions with responses on Likert Scale as strongly disagree, disagree, agree and strongly agree coded as 1, 2, 3 and 4, respectively. Data was analysed on SPSS version 22. Results: There were 78 (57 percent) male and 59 (43 percent) female students out of 137, with mean age of 22.59 ± 0.74 years. The response rate was 68.5 percent. Cronbach's Alpha test was 0.84 showing high reliability. The mean of sum of all the 23 items was 63.85 ± 8.71, whereas item means was 2.78 ± 0.38, reflecting a high inclination of students towards skill laboratory training. Frequency of students responding in favour of skill laboratory training was significantly high (p < 0.05). Conclusion: Medical students perceived skill laboratory training as a favoured learning strategy as compared to practising on real patients for acquisition of various aspects of clinical skills, knowledge and attitude. (author)

Bioremediation case studies: Abstracts. Final report

International Nuclear Information System (INIS)

Devine, K.

1992-03-01

The report contains abstracts of 132 case studies of bioremediation technology applied to hazardous waste clean-up. It was prepared to compile bioremediation studies in a variety of locations and treating diverse contaminants, most of which were previously undocumented. All data are based on vendor-supplied information and there was no opportunity to independently confirm its accuracy. These 132 case studies, from 10 different biotechnology companies, provide users with reference information about on-going and/or completed field applications and studies. About two-thirds of the cases were at full-scale clean-up level with the remainder at pilot or laboratory scale. In 74 percent of the cases, soil was at least one of the media treated. Soil alone accounts for 46 percent of the cases. Petroleum-related wastes account for the largest contaminant with 82 cases. Thirty-one states are represented in the case studies

Knowledge, attitude, and practice (KAP) of 'teaching laboratory' technicians towards laboratory safety and waste management: a pilot interventional study.

Science.gov (United States)

El-Gilany, A-H; El-Shaer, S; Khashaba, E; El-Dakroory, S A; Omar, N

2017-06-01

A quasi-experimental study was performed on 20 technicians working in the Faculty of Medicine, Mansoura University, Egypt. The knowledge, attitude, and practice (KAP) of laboratory technicians was measured before and two months after enrolling them in an intervention programme about laboratory best practice procedures. The programme addressed laboratory safety and medical waste management. The assessment was performed using a validated Arabic self-administered questionnaire. Pre- and post-intervention scores were compared using non-parametric tests. There are significant increases in the scores of KAP after implementation of the training programme. Copyright © 2017 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

Environmental assessment for construction and operation of a Human Genome Laboratory at Lawrence Berkeley Laboratory, Berkeley, California

Energy Technology Data Exchange (ETDEWEB)

NONE

1994-12-01

Lawrence Berkeley Laboratory (LBL) proposes to construct and operate a new laboratory for consolidation of current and future activities of the Human Genome Center (HGC). This document addresses the potential direct, indirect, and cumulative environmental and human-health effects from the proposed facility construction and operation. This document was prepared in accordance the National Environmental Policy Act of 1969 (United States Codes 42 USC 4321-4347) (NEPA) and the US Department of Energy`s (DOE) Final Rule for NEPA Implementing Procedures [Code of Federal Regulations 10CFR 1021].

DYNAMICS OF POLYMERS AT INTERFACES; FINAL

International Nuclear Information System (INIS)

SMITH, G.S.; MAJEWSKI, J.

1999-01-01

This is the final report of a three-year, Laboratory-Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). This project addresses fundamental questions concerning the behavior of polymers at interfaces: (1) What processes control the formation of an adsorbed layer on a clean surface? (2) What processes control the displacement of preadsorbed polymers? (3) Can one accurately predict the structure of polymer layers? To answer these questions, using neutron reflectivity, we have studied adsorbed layers of the polymer poly(methyl methacrylate) (PMMA) onto a quartz substrate. The polymer density profiles were derived from the neutron reflectivity data. We have shown that dry films exhibit behavior predicted by mean-field theory in that the equilibrated layer thickness scales with the molecular weight of the polymer. Also, we find that the profiles of the polymers in solution qualitatively agree with those predicted by reflected random walk (RRW) theories, yet the profiles are not in quantitative agreement

Test plan for ISV laboratory-pyrolysis testing

Energy Technology Data Exchange (ETDEWEB)

McAtee, R.E.

1991-09-01

The objective of the laboratory-pyrolysis studies is to obtain information on the high temperature (< 1200{degree}C) degradation and alteration of organic chemicals and materials similar to those found in the Radioactive Waste Management Complex, Pit 9. This test plan describes experimental procedures, sampling and analysis strategy, sampling procedures, sample control, and document management. It addresses safety issues in the experimental apparatus and procedures, personal training, and hazardous waste disposal. Finally, it describes the data quality objectives using the EPA tiered approach to treatability studies to define where research/scoping tests fit into these studies and the EPA analytical levels required for the tests.

Quality in laboratory medicine: 50years on.

Science.gov (United States)

Plebani, Mario

2017-02-01

The last 50years have seen substantial changes in the landscape of laboratory medicine: its role in modern medicine is in evolution and the quality of laboratory services is changing. The need to control and improve quality in clinical laboratories has grown hand in hand with the growth in technological developments leading to an impressive reduction of analytical errors over time. An essential cause of this impressive improvement has been the introduction and monitoring of quality indicators (QIs) such as the analytical performance specifications (in particular bias and imprecision) based on well-established goals. The evolving landscape of quality and errors in clinical laboratories moved first from analytical errors to all errors performed within the laboratory walls, subsequently to errors in laboratory medicine (including errors in test requesting and result interpretation), and finally, to a focus on errors more frequently associated with adverse events (laboratory-associated errors). After decades in which clinical laboratories have focused on monitoring and improving internal indicators of analytical quality, efficiency and productivity, it is time to shift toward indicators of total quality, clinical effectiveness and patient outcomes. Copyright © 2016 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

Resolving complex research data management issues in biomedical laboratories: Qualitative study of an industry-academia collaboration.

Science.gov (United States)

Myneni, Sahiti; Patel, Vimla L; Bova, G Steven; Wang, Jian; Ackerman, Christopher F; Berlinicke, Cynthia A; Chen, Steve H; Lindvall, Mikael; Zack, Donald J

2016-04-01

This paper describes a distributed collaborative effort between industry and academia to systematize data management in an academic biomedical laboratory. Heterogeneous and voluminous nature of research data created in biomedical laboratories make information management difficult and research unproductive. One such collaborative effort was evaluated over a period of four years using data collection methods including ethnographic observations, semi-structured interviews, web-based surveys, progress reports, conference call summaries, and face-to-face group discussions. Data were analyzed using qualitative methods of data analysis to (1) characterize specific problems faced by biomedical researchers with traditional information management practices, (2) identify intervention areas to introduce a new research information management system called Labmatrix, and finally to (3) evaluate and delineate important general collaboration (intervention) characteristics that can optimize outcomes of an implementation process in biomedical laboratories. Results emphasize the importance of end user perseverance, human-centric interoperability evaluation, and demonstration of return on investment of effort and time of laboratory members and industry personnel for success of implementation process. In addition, there is an intrinsic learning component associated with the implementation process of an information management system. Technology transfer experience in a complex environment such as the biomedical laboratory can be eased with use of information systems that support human and cognitive interoperability. Such informatics features can also contribute to successful collaboration and hopefully to scientific productivity. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

SRC-I demonstration plant analytical laboratory methods manual. Final technical report

Energy Technology Data Exchange (ETDEWEB)

Klusaritz, M.L.; Tewari, K.C.; Tiedge, W.F.; Skinner, R.W.; Znaimer, S.

1983-03-01

This manual is a compilation of analytical procedures required for operation of a Solvent-Refined Coal (SRC-I) demonstration or commercial plant. Each method reproduced in full includes a detailed procedure, a list of equipment and reagents, safety precautions, and, where possible, a precision statement. Procedures for the laboratory's environmental and industrial hygiene modules are not included. Required American Society for Testing and Materials (ASTM) methods are cited, and ICRC's suggested modifications to these methods for handling coal-derived products are provided.

Students' motivation toward laboratory work in physiology teaching.

Science.gov (United States)

Dohn, Niels Bonderup; Fago, Angela; Overgaard, Johannes; Madsen, Peter Teglberg; Malte, Hans

2016-09-01

The laboratory has been given a central role in physiology education, and teachers report that it is motivating for students to undertake experimental work on live animals or measuring physiological responses on the students themselves. Since motivation is a critical variable for academic learning and achievement, then we must concern ourselves with questions that examine how students engage in laboratory work and persist at such activities. The purpose of the present study was to investigate how laboratory work influences student motivation in physiology. We administered the Lab Motivation Scale to assess our students' levels of interest, willingness to engage (effort), and confidence in understanding (self-efficacy). We also asked students about the role of laboratory work for their own learning and their experience in the physiology laboratory. Our results documented high levels of interest, effort, and self-efficacy among the students. Correlation analyses were performed on the three motivation scales and exam results, yet a significant correlation was only found between self-efficacy in laboratory work and academic performance at the final exam. However, almost all students reported that laboratory work was very important for learning difficult concepts and physiological processes (e.g., action potential), as the hands-on experiences gave a more concrete idea of the learning content and made the content easier to remember. These results have implications for classroom practice as biology students find laboratory exercises highly motivating, despite their different personal interests and subject preferences. This highlights the importance of not replacing laboratory work by other nonpractical approaches, for example, video demonstrations or computer simulations. Copyright © 2016 The American Physiological Society.

Application of Lean-Six Sigma Approach in a Laboratory Experimental Case Study

Directory of Open Access Journals (Sweden)

Hashim Raza Rizvi

2013-12-01

Full Text Available Laboratory experiments are a conventional activity performed at academic institutions, government and private organizations. These experimental studies provide the basis for new inventions in the field of science and engineering. Laboratory experiments are conducted on the basis of provided guidelines, already established by different standard organizations like ASTM, AASHTO etc. This article is based on a case study in which the process of an experiment is examined on the basis of Value Stream Maps (VSM and potential improvement possibilities have been identified. After determining the potential waste, appropriate Lean tools are selected to implement and observe the improvements. The process is examined after application of the Lean tools and a comparison is performed. University laboratory environment can be improved considerably by applying Lean Tools. MUDA application reduced the total work time from 90.75 hours and 10-CD to 63.75 hours and 7-CD hence saving, 27 hours and 3-CD for one experiment. This is remarkable achievement of this application. Heijunka application provided the students equal workload and they performed explicitly better than they used to. 5-S tool provided the students the opportunity to manage the laboratory in an effective and clean way. Safety of the students is a very major concern at university laboratory environment. 5-S not only upgraded the laboratory overall performance, but it significantly raised the safety standards of the laboratory. More application of the Lean Tools should be exercised explored to have more effective and efficient university laboratory experimental environment.

Final focus systems for linear colliders

International Nuclear Information System (INIS)

Helm, R.; Irwin, J.

1992-08-01

Final focus systems for linear colliders present many exacting challenges in beam optics, component design, and beam quality. Efforts to resolve these problems as they relate to a new generation of linear colliders are under way at several laboratories around the world. We will outline criteria for final focus systems and discuss the current state of understanding and resolution of the outstanding problems. We will discuss tolerances on alignment, field quality and stability for optical elements, and the implications for beam parameters such as emittance, energy spread, bunch length, and stability in position and energy. Beam-based correction procedures, which in principle can alleviate many of the tolerances, will be described. Preliminary results from the Final Focus Test Beam (FFTB) under construction at SLAC will be given. Finally, we mention conclusions from operating experience at the Stanford Linear Collider (SLC)

Final focus systems for linear colliders

International Nuclear Information System (INIS)

Helm, R.; Irwing, J.

1992-01-01

Final focus systems for linear colliders present many exacting challenges in beam optics, component design, and beam quality. Efforts to resolve these problems as they relate to a new generation of linear colliders are under way at several laboratories around the world. We outline criteria for final focus systems and discuss the current state of understanding and resolution of the outstanding problems. We discuss tolerances on alignment, field quality and stability for optical elements, and the implications for beam parameters such as emittance, energy spread , bunch length, and stability in position and energy. Beam-based correction procedures, which in principle can alleviate many of the tolerances, are described. Preliminary results from the Final Focus Test Beam (FFTB) under construction at SLAC are given. Finally, we mention conclusions from operating experience at the Stanford Linear Collider (SLC). (Author) 16 refs., 4 tabs., 6 figs

Safety in the Chemical Laboratory. Epidemiology of Accidents in Academic Chemistry Laboratories, Part 2. Accident Intervention Study, Legal Aspects, and Observations.

Science.gov (United States)

Hellmann, Margaret A.; And Others

1986-01-01

Reports on a chemistry laboratory accident intervention study conducted throughout the state of Colorado. Addresses the results of an initial survey of institutions of higher learning. Discusses some legal aspects concerning academic chemistry accidents. Provides some observations about academic chemistry laboratory accidents on the whole. (TW)

Chemical laboratory hazardous waste management at a DOE multiprogram national laboratory

International Nuclear Information System (INIS)

Turner, P.J.

1990-03-01

Pacific Northwest Laboratory (PNL), a United States Department of Energy (DOE) Multiprogram Energy Laboratory, is establishing a program for management of diverse small-quantity laboratory waste generated on site. Although the main emphasis of this program is ''cradle-to-grave'' tracking and treatment of hazardous chemical waste and mixed waste, low-level radioactive and transuranic (TRU) waste is also being included. With the program in operation, more than 95% of all regulated waste will be treated or destroyed on site. The cost savings will return the original investment in under six years and decrease the liability to PNL and DOE -- a benefit with a potentially greater economic value. Tracking of hazardous waste will be mediated by a computer-based inventory and tracking system. The system will track all hazardous materials from receipt through final disposition, whether the material is destroyed or treated for disposal. It will allow user access to handling and hazards information as well as provide an updated inventory by location, user, and hazard type. Storage and treatment of waste will be performed by at least four facilities, made operational in three phases. 6 figs

NVN 5694 intra laboratory validation. Feasibility study for interlaboratory- validation

International Nuclear Information System (INIS)

Voors, P.I.; Baard, J.H.

1998-11-01

Within the project NORMSTAR 2 a number of Dutch prenormative protocols have been defined for radioactivity measurements. Some of these protocols, e.g. the Dutch prenormative protocol NVN 5694, titled Methods for radiochemical determination of polonium-210 and lead-210, have not been validated, neither by intralaboratory nor interlaboratory studies. Validation studies are conducted within the framework of the programme 'Normalisatie and Validatie van Milieumethoden 1993-1997' (Standardization and Validation of test methods for environmental parameters) of the Dutch Ministry of Housing, Physical Planning and the Environment (VROM). The aims of this study were (a) a critical evaluation of the protocol, (b) investigation on the feasibility of an interlaboratory study, and (c) the interlaboratory validation of NVN 5694. The evaluation of the protocol resulted in a list of deficiencies varying from missing references to incorrect formulae. From the survey by interview it appeared that for each type of material, there are 4 to 7 laboratories willing to participate in a interlaboratory validation study. This reflects the situation in 1997. Consequently, if 4 or 6 (the minimal number) laboratories are participating and each laboratory analyses 3 subsamples, the uncertainty in the repeatability standard deviation is 49 or 40 %, respectively. If the ratio of reproducibility standard deviation to the repeatability standard deviation is equal to 1 or 2, then the uncertainty in the reproducibility standard deviation increases from 42 to 67 % and from 34 to 52 % for 4 or 6 laboratories, respectively. The intralaboratory validation was established on four different types of materials. Three types of materials (milkpowder condensate and filter) were prepared in the laboratory using the raw material and certified Pb-210 solutions, and one (sediment) was obtained from the IAEA. The ECN-prepared reference materials were used after testing on homogeneity. The pre-normative protocol can

The testing effect for mediator final test cues and related final test cues in online and laboratory experiments

NARCIS (Netherlands)

L.C. Coppens; P.P.J.L. Verkoeijen; S. Bouwmeester; R.M.J.P. Rikers

2016-01-01

Background The testing effect is the finding that information that is retrieved during learning is more often correctly retrieved on a final test than information that is restudied. According to the semantic mediator hypothesis the testing effect arises because retrieval practice of cue-target

The testing effect for mediator final test cues and related final test cues in online and laboratory experiments

NARCIS (Netherlands)

Coppens, Leonora C.; Verkoeijen, Peter P. J. L.; Bouwmeester, Samantha; Rikers, Remy M. J. P.

2016-01-01

Background The testing effect is the finding that information that is retrieved during learning is more often correctly retrieved on a final test than information that is restudied. According to the semantic mediator hypothesis the testing effect arises because retrieval practice of cue-target pairs

Laboratory and pilot plant studies for the recovery of uranium from phosphoric acid by the D2EHPA-TOPO process

International Nuclear Information System (INIS)

Botella, T.; Gasos, P.

1989-01-01

The activities and costs involved in laboratory and pilot plant studies are discussed as applied to the D2EHPA-TOPO process. The overall capital investment (including engineering) for a plant with a throughput of 12 cubic meters of acid/day has been estimated to be around one million US dollars. Operating costs per year, without considering amortization and labor, are over 20,000 US dollars. A total time of 3,5 years (including engineering, purchase and pilot plant tests) could be needed to obtain the information required for final scale-up. (author). 40 refs, 1 fig., 5 tabs

[Quality assessment of microscopic examination in tuberculosis diagnostic laboratories: a preliminary study].

Science.gov (United States)

Simşek, Hülya; Ceyhan, Ismail; Tarhan, Gülnur; Güner, Uğur

2010-10-01

Recently, the diagnosis of pulmonary tuberculosis (TB) has based on smear microscopy in the Direct Observed Treatment Strategy (DOTS) programme which provides the basis of treatment worldwide. Microscopic detection of AFB (Acid-Fast Bacilli) is one of the main components in the National TB Control Programmes (NTCP). Precision level in microscopy procedures and evaluations are the most important steps for accurate diagnosis of the disease and to initiate proper treatment. Therefore, the external quality assessment (EQA) is the most important implement to provide the reliability and validity of tests. In countries where NTCP are performed, this task is fulfilled by the National Reference Laboratories (NRL) according to the guidelines of the World Health Organization (WHO). For this purpose a pilot study was initiated by the central NRL of Turkey for EQA of AFB smear microscopy as part of the NTCP on January 1, 2005. A total of 5 laboratories of which 2 were district TB laboratories (A, B), 2 were tuberculosis control dispensaries (C, D), 1 was a national reference laboratory (E), participated in this study. Blind re-checking method (re-examination of randomly selected slides) was used for the evaluation, and the slides were sent to the central NRL with 3 months interval, four times a year, selected according to LQAS (Lot Quality Assurance Sampling) guides. In the re-evaluation of the slides, false positivity (FP), false negativity (FN) and quantification errors (QE) were noted. Laboratory A, sent totally 525 slides between January 1, 2005 and April 1, 2008. In the result of re-checking, 514 (97.9%) slides were found concordant, and 11 (2.1%) were discordant (10 FP, 1 FN). Laboratory B, participated in the study between October 1, 2005 and July 1, 2006 and of the 67 re-examined slides, 60 (89.5%) were concordant and 7 (10.5%) were discordant (2 FP, 0 FN, 5 QE). Laboratory C, sent 235 slides between January 1, 2005 and April 1, 2006; of them 218 (92.8%) were detected

Distributed intelligence versus central laboratory

International Nuclear Information System (INIS)

Halling, H.

1983-01-01

After a discussion of the main tasks in a nuclear laboratory like overall experiment planning, sample production and management, performance of experiments, data processing and report generation the essential disadvantages of centralised systems are shown and the proper measures for overcoming those by distribution are discussed. Finally possible shortcomings due to improper design and management of distributed architectures are shown. (author)

Laboratory Experiments and Instrument Intercomparison Studies of Carbonaceous Aerosol Particles

Energy Technology Data Exchange (ETDEWEB)

Davidovits, Paul [Boston College, Chestnut Hill, MA (United States)

2015-10-20

Aerosols containing black carbon (and some specific types of organic particulate matter) directly absorb incoming light, heating the atmosphere. In addition, all aerosol particles backscatter solar light, leading to a net-cooling effect. Indirect effects involve hydrophilic aerosols, which serve as cloud condensation nuclei (CCN) that affect cloud cover and cloud stability, impacting both atmospheric radiation balance and precipitation patterns. At night, all clouds produce local warming, but overall clouds exert a net-cooling effect on the Earth. The effect of aerosol radiative forcing on climate may be as large as that of the greenhouse gases, but predominantly opposite in sign and much more uncertain. The uncertainties in the representation of aerosol interactions in climate models makes it problematic to use model projections to guide energy policy. The objective of our program is to reduce the uncertainties in the aerosol radiative forcing in the two areas highlighted in the ASR Science and Program Plan. That is, (1) addressing the direct effect by correlating particle chemistry and morphology with particle optical properties (i.e. absorption, scattering, extinction), and (2) addressing the indirect effect by correlating particle hygroscopicity and CCN activity with particle size, chemistry, and morphology. In this connection we are systematically studying particle formation, oxidation, and the effects of particle coating. The work is specifically focused on carbonaceous particles where the uncertainties in the climate relevant properties are the highest. The ongoing work consists of laboratory experiments and related instrument inter-comparison studies both coordinated with field and modeling studies, with the aim of providing reliable data to represent aerosol processes in climate models. The work is performed in the aerosol laboratory at Boston College. At the center of our laboratory setup are two main sources for the production of aerosol particles: (a

The Qualitative-Quantitative Analysis and the Study of Personnel's Awareness of the Management Strategies of the Wastes of Medical Diagnostic Laboratories of Rasht, in 2009

Directory of Open Access Journals (Sweden)

Nabizadeh R.

2012-01-01

Full Text Available Background and Objectives: Waste produced by health and treatment centers (hospitals including medical diagnostic laboratories is one of the sources of municipal waste production. Waste produced by medical diagnostic laboratories due to the existence of pathogens and infectious materials by high importance is one of the environmental issues. This survey has been done on the qualitative-quantitative analytical bases, and the investigation has focused on the management strategies of the waste material of medical diagnostic laboratories of Rasht, Iran in 2009. Methods: In this descriptive study, samples were collected from 19 medical diagnostic laboratories of Rasht in 3 consecutive days (Monday, Tuesday and Wednesday every week, after filling the questionnaire and interviewing with the managers. Then, the samples were separated manually, and divided into 46 different constituents and weighed. Next, the constituents were classified based on characteristics and potentiality of being hazardous.Results: The total amount of annual waste production by the medical diagnostic laboratories of Rasht is 25785.143kg. In this study, the share of manufacturing conventional waste (domestic type wastes, especially infectious, chemical, pharmaceutical, and radioactive wastes were 1.16%, 95.34%, 1.42% and 2.08%, respectively. The highest and lowest amount of waste production relates to plastic materials and wood which are 48.37 and 0.43%, respectively. In this study sharp cutting things were calculated to be 10.52%. Furthermore, 84 percent of the managers of the medical diagnostic laboratories had not had enough information of the circulars and instructions on the enforceable management strategies of the medical wastes.Conclusion: Concerning the management of the medical waste production in the medical diagnostic laboratories, it is suggested that the managers and the personnel be trained on the separation, collection, and disinfection techniques and final disposal

ESTABLISHMENT OF AN ENVIRONMENTAL CONTROL TECHNOLOGY LABORATORY WITH A CIRCULATING FLUIDIZED-BED COMBUSTION SYSTEM

Energy Technology Data Exchange (ETDEWEB)

Wei-Ping Pan; Andy Wu; John T. Riley

2005-04-30

This report is to present the progress made on the project ''Establishment of an Environmental Control Technology Laboratory (ECTL) with a Circulating Fluidized-Bed Combustion (CFBC) System'' during the period January 1, 2005 through March 31, 2005. The following tasks have been completed. First, the renovation of the new Combustion Laboratory is nearly complete, and the construction of the Circulating Fluidized-Bed (CFB) Combustor Building is in the final stages. Second, the fabrication and manufacture of the CFBC Facility is being discussed with a potential contractor. Discussions with potential contactor regarding the availability of materials and current machining capabilities have resulted in the modification of the original designs. The selection of the fabrication contractor for the CFBC Facility is expected during the next quarter. Third, co-firing experiments conducted with coal and chicken waste have been initiated in the laboratory-scale simulated fluidized-bed facility. The experimental results from this study are presented in this report. Finally, the proposed work for the next quarter is described in this report.

Final Environmental Impact Statement and Environmental Impact Report for continued operation of Lawrence Livermore National Laboratory and Sandia National Laboratories, Livermore

International Nuclear Information System (INIS)

1992-08-01

The US Department of Energy (DOE) and the Regents of the University of California (UC) propose the continued operation, including near-term proposed projects, of the Lawrence Livermore National Laboratory (LLNL). In addition, DOE proposes the continued operation, including near-term proposed projects, of Sandia National Laboratories, Livermore (SNL, Livermore). Continued operation plus proposed projects at the two Laboratories is needed so that the research and development missions established by Congress and the President can continue to be supported. As provided and encouraged by the National Environmental Policy Act (NEPA) and the California Environmental Quality Act (CEQA), DOE and UC have prepared this document as a joint Environmental Impact Statement (EIS) and Environmental Impact Report (EIR) to analyze the impacts of the proposed action. In addition, this document discusses a no action alternative for continuing operations at FY 1992 funding levels without further growth, a modification of operations alternative focused on specific adverse environmental impacts of operations or facilities, and a shutdown and decommissioning alternative. This document also examines the alternative of UC discontinuing its management of LLNL after the current contract expires on September 30, 1992. The environmental documentation process provides information to the public, government agencies, and decision makers about the environmental impacts of implementing the proposed and alternative actions. In addition, this environmental documentation identifies alternatives and possible ways to reduce or prevent environmental impacts. A list of the issues raised through the EIS/EIR scoping process is presented

Applications of neutrons for laboratory and industrial activation analysis problems

International Nuclear Information System (INIS)

Szabo, Elek; Bakos, Laszlo

1986-01-01

This chapter presents some particular applications and case studies of neutrons in activation analysis for research and industrial development purposes. The reactor neutrons have been applied in Hungarian laboratories for semiconductor research, for analysis of geological (lunar) samples, and for a special comparator measurement of samples. Some industrial applications of neutron generator and sealed sources for analytical problems are presented. Finally, prompt neutron activation analysis is outlined briefly. (R.P.)

Bioaccumulation, distribution and elimination of chlordecone in the giant freshwater prawn Macrobrachium rosenbergii: Field and laboratory studies.

Science.gov (United States)

Lafontaine, Anne; Gismondi, Eric; Dodet, Nathalie; Joaquim-Justo, Célia; Boulangé-Lecomte, Céline; Caupos, Fanny; Lemoine, Soazig; Lagadic, Laurent; Forget-Leray, Joëlle; Thomé, Jean-Pierre

2017-10-01

Chlordecone is a persistent organochlorine pesticide that has been widely used in Guadeloupe (French West Indies) to control the banana weevil Cosmopolites sordidus from 1972 to 1993. A few years after its introduction, widespread contamination of soils, rivers, wild animals and aquatic organisms was reported. Although high chlordecone concentrations have been reported in several crustacean species, its uptake, internal distribution, and elimination in aquatic species have never been described. This study aimed at investigating the accumulation and tissue distribution of chlordecone in the giant freshwater prawn Macrobrachium rosenbergii, using both laboratory (30 days exposure) and field (8 months exposure) approaches. In addition, depuration in chlordecone-free water was studied. Results showed that chlordecone bioconcentration in prawns was dose-dependent and time-dependent. Moreover, females appeared to be less contaminated than males after 5 and 7 months of exposure, probably due to successive spawning leading in the elimination of chlordecone through the eggs. Chlordecone distribution in tissues of exposed prawns showed that cephalothorax organs, mainly represented by the hepatopancreas, was the most contaminated. Results also showed that chlordecone was accumulated in cuticle, up to levels of 40% of the chlordecone body burden, which could be considered as a depuration mechanism since chlordecone is eliminated with the exuviae during successive moults. Finally, this study underlined the similarity of results obtained in laboratory and field approaches, which highlights their complementarities in the chlordecone behaviour understanding in M. rosenbergii. Copyright © 2017 Elsevier Ltd. All rights reserved.

Final report for tank 241-BX-104 push mode core 126 and 127

International Nuclear Information System (INIS)

Hu, T.A.

1996-01-01

This is the final sample analysis report for tank 241-BX-104 (BX-104), cores 126 and 127. Two segments from each core yielded a total of 11 samples which were analyzed. The data quality objectives (DQOs) applicable to this sampling event were the Safety Screening DQO (Dukelow et al. 1995) and the Organic Safety DQO (Turner et al. 1995). The samples were received, extruded and analyzed at PNNL 325 Analytical Chemistry Laboratory (ACL). The analyses were performed in accordance with the Sample Analysis Plan (Gretsinger 1996) and indicated that the tank is safe with respect to the criteria in the Safety Screening and Organic DQO. Detailed analytical results were described in the analytical laboratory 45-day Report (Attachment 1, WHC-SD-WM-DP-171, REV. 0) and final report (Attachment 2, PNL-BX-104 REV.1) prepared by PNNL, 325 Laboratory. Corrections and/or exceptions to the PNNL final report are provided

A refuge for inorganic chemistry: Bunsen's Heidelberg laboratory.

Science.gov (United States)

Nawa, Christine

2014-05-01

Immediately after its opening in 1855, Bunsen's Heidelberg laboratory became iconic as the most modern and best equipped laboratory in Europe. Although comparatively modest in size, the laboratory's progressive equipment made it a role model for new construction projects in Germany and beyond. In retrospect, it represents an intermediate stage of development between early teaching facilities, such as Liebig's laboratory in Giessen, and the new 'chemistry palaces' that came into existence with Wöhler's Göttingen laboratory of 1860. As a 'transition laboratory,' Bunsen's Heidelberg edifice is of particular historical interest. This paper explores the allocation of spaces to specific procedures and audiences within the laboratory, and the hierarchies and professional rites of passage embedded within it. On this basis, it argues that the laboratory in Heidelberg was tailored to Bunsen's needs in inorganic and physical chemistry and never aimed at a broad-scale representation of chemistry as a whole. On the contrary, it is an example of early specialisation within a chemical laboratory preceding the process of differentiation into chemical sub-disciplines. Finally, it is shown that the relatively small size of this laboratory, and the fact that after ca. 1860 no significant changes were made within the building, are inseparably connected to Bunsen's views on chemistry teaching.

Idaho National Engineering and Environmental Laboratory Environmental Technologies Proof-of-Concepts. Final report FY-96

Energy Technology Data Exchange (ETDEWEB)

Barrie, S.L.; Carpenter, G.S.; Crockett, A.B. [and others

1997-04-01

The Idaho National Engineering and Environmental Laboratory Environmental Technologies Proof-of-Concept Project was initiated for the expedited development of new or conceptual technologies in support of groundwater fate, transport, and remediation; buried waste characterization, retrieval, and treatment; waste minimization/pollution prevention; and spent fuel handling and storage. In Fiscal Year 1996, The Idaho National Engineering and Environmental Laboratory proposed 40 development projects and the Department of Energy funded 15. The projects proved the concepts of the various technologies, and all the technologies contribute to successful environmental management.

Idaho National Engineering and Environmental Laboratory Environmental Technologies Proof-of-Concepts. Final report FY-96

International Nuclear Information System (INIS)

Barrie, S.L.; Carpenter, G.S.; Crockett, A.B.

1997-04-01

The Idaho National Engineering and Environmental Laboratory Environmental Technologies Proof-of-Concept Project was initiated for the expedited development of new or conceptual technologies in support of groundwater fate, transport, and remediation; buried waste characterization, retrieval, and treatment; waste minimization/pollution prevention; and spent fuel handling and storage. In Fiscal Year 1996, The Idaho National Engineering and Environmental Laboratory proposed 40 development projects and the Department of Energy funded 15. The projects proved the concepts of the various technologies, and all the technologies contribute to successful environmental management

Preliminary study: Formaldehyde exposure in laboratories of Sharjah university in UAE

OpenAIRE

Ahmed, Hafiz Omer

2011-01-01

Objectives : Laboratory technicians, students, and instructors are at high risk, because they deal with chemicals including formaldehyde. Thus, this preliminary study was conducted to measure the concentration of formaldehyde in the laboratories of the University of Sharjah in UAE. Materials and Methods: Thirty-two air samples were collected and analyzed for formaldehyde using National Institute for Occupational Safety and Health (NIOSH) method 3500. In this method, formaldehyde reacts with c...

COLAB: A Laboratory Environment for Studying Analyst Sensemaking and Collaboration

National Research Council Canada - National Science Library

Morrison, Clayton T; Cohen, Paul R

2005-01-01

COLAB is a laboratory for studying tools that facilitate collaboration and sensemaking among groups of human analysts as they build interpretations of unfolding situations based on accruing intelligence data...

Selecting automation for the clinical chemistry laboratory.

Science.gov (United States)

Melanson, Stacy E F; Lindeman, Neal I; Jarolim, Petr

2007-07-01

Laboratory automation proposes to improve the quality and efficiency of laboratory operations, and may provide a solution to the quality demands and staff shortages faced by today's clinical laboratories. Several vendors offer automation systems in the United States, with both subtle and obvious differences. Arriving at a decision to automate, and the ensuing evaluation of available products, can be time-consuming and challenging. Although considerable discussion concerning the decision to automate has been published, relatively little attention has been paid to the process of evaluating and selecting automation systems. To outline a process for evaluating and selecting automation systems as a reference for laboratories contemplating laboratory automation. Our Clinical Chemistry Laboratory staff recently evaluated all major laboratory automation systems in the United States, with their respective chemistry and immunochemistry analyzers. Our experience is described and organized according to the selection process, the important considerations in clinical chemistry automation, decisions and implementation, and we give conclusions pertaining to this experience. Including the formation of a committee, workflow analysis, submitting a request for proposal, site visits, and making a final decision, the process of selecting chemistry automation took approximately 14 months. We outline important considerations in automation design, preanalytical processing, analyzer selection, postanalytical storage, and data management. Selecting clinical chemistry laboratory automation is a complex, time-consuming process. Laboratories considering laboratory automation may benefit from the concise overview and narrative and tabular suggestions provided.

A comparative study of the systems for neutronics calculations used in Los Alamos Scientific Laboratory (LASL) and Argonne National Laboratory (ANL)

International Nuclear Information System (INIS)

Amorim, E.S. do; D'Oliveira, A.B.; Oliveira, E.C. de.

1980-11-01

A comparative study of the systems for neutronics calculations used in Los Alamos Scientific Laboratory (LASL) and Argonne National Laboratory (ANL) has been performed using benchmark results available in the literature, in order to analyse tghe convenience of using the respective codes MINX/NJOY and ETOE/MC 2 -2 for performing neutronics calculations in course at the Divisao de Estudos Avancados. (Author) [pt

Application of laboratory microtomography to the study of mineralized tissues

International Nuclear Information System (INIS)

Elliot, J.C.; Davis, G.R.; Anderson, P.; Wong, F.S.L.; Dowker, S.E.P.; Mercer, C.E.

1997-01-01

The principles of microtomography are briefly presented and recent studies of mineralized tissues using laboratory and synchrotron X-ray sources are reviewed. Results are given of investigations undertaken with laboratory systems using either a 1 st generation (single beam of 15 mu m and energy dispersive detector) or a novel 4 th generation system with 2-D detector that can provide 3-D images with vowels of 38x38x38 mu m ''3 of specimens with diameter up to 40 mm. Studies include mineral concentration distributions in cortical bone trabecular structure in a human vertebral body, cracking of bone under compression in situ and root canal obturation and Er: YAG laser application to enamel and dentine. Future applications of microtomography to the study of mineralized tissues and their interaction with biomaterials are discussed.(Author) 31 refs

ICPP injection well alternative project, Idaho National Engineering Laboratory. Final report

International Nuclear Information System (INIS)

1980-10-01

The Idaho Chemical Processing Plant (ICPP) portion of the Idaho National Engineering Laboratory (INEL) has been obtaining water needed for its operations from the Snake River aquifer, which occupies the entire region underlying the site. Most of this water has been used for cooling operating equipment, while a small portion has found various process uses. After passing through the ICPP process area, these waters are then returned to the aquifer. A small portion (about 1%) of the returned stream contains measurable amounts of radioactivity derived from the miscellaneous process users. This report and the recommendations contained herein are based upon stream flows projected for 1985 as supplied by DOE for the ICPP. 26 different alternatives for handling cooling water, chemical, and low level radioactive water disposal are examined. These cases are considered from technical, environmental, safety, and economic points of view. The level of detail is sufficient to eliminate non-viable cases, and to identify those which offer improvements over present practice. The Environmental/Safety Risk Factors were evaluated on a qualitative comparison basis only. Before a recommended improvement is incorporated into the waste disposal system, a conceptual design study should be made which would evaluate all those secondary effects and environmental factors that, by the very nature of the screening process, this study has not provided. Certain synergistic combinations have been noted and are discussed. This report does note whether the operations considered are in regulatory compliance, or are likely to be capable of providing lasting improvement to the waste water system. Qualitative comparisons were made between the various alternatives to confirm their relationship with applicable standards

Full-Length High-Temperature Severe Fuel Damage Test No. 5: Final safety analysis

International Nuclear Information System (INIS)

Lanning, D.D.; Lombardo, N.J.; Panisko, F.E.

1993-09-01

This report presents the final safety analysis for the preparation, conduct, and post-test discharge operation for the Full-Length High Temperature Experiment-5 (FLHT-5) to be conducted in the L-24 position of the National Research Universal (NRU) Reactor at Chalk River Nuclear Laboratories (CRNL), Ontario, Canada. The test is sponsored by an international group organized by the US Nuclear Regulatory Commission. The test is designed and conducted by staff from Pacific Northwest Laboratory with CRNL staff support. The test will study the consequences of loss-of-coolant and the progression of severe fuel damage

Purdue Hydrogen Systems Laboratory

Energy Technology Data Exchange (ETDEWEB)

Jay P Gore; Robert Kramer; Timothee L Pourpoint; P. V. Ramachandran; Arvind Varma; Yuan Zheng

2011-12-28

The Hydrogen Systems Laboratory in a unique partnership between Purdue University's main campus in West Lafayette and the Calumet campus was established and its capabilities were enhanced towards technology demonstrators. The laboratory engaged in basic research in hydrogen production and storage and initiated engineering systems research with performance goals established as per the USDOE Hydrogen, Fuel Cells, and Infrastructure Technologies Program. In the chemical storage and recycling part of the project, we worked towards maximum recycling yield via novel chemical selection and novel recycling pathways. With the basic potential of a large hydrogen yield from AB, we used it as an example chemical but have also discovered its limitations. Further, we discovered alternate storage chemicals that appear to have advantages over AB. We improved the slurry hydrolysis approach by using advanced slurry/solution mixing techniques. We demonstrated vehicle scale aqueous and non-aqueous slurry reactors to address various engineering issues in on-board chemical hydrogen storage systems. We measured the thermal properties of raw and spent AB. Further, we conducted experiments to determine reaction mechanisms and kinetics of hydrothermolysis in hydride-rich solutions and slurries. We also developed a continuous flow reactor and a laboratory scale fuel cell power generation system. The biological hydrogen production work summarized as Task 4.0 below, included investigating optimal hydrogen production cultures for different substrates, reducing the water content in the substrate, and integrating results from vacuum tube solar collector based pre and post processing tests into an enhanced energy system model. An automated testing device was used to finalize optimal hydrogen production conditions using statistical procedures. A 3 L commercial fermentor (New Brunswick, BioFlo 115) was used to finalize testing of larger samples and to consider issues related to scale up

Purdue Hydrogen Systems Laboratory

International Nuclear Information System (INIS)

Gore, Jay P.; Kramer, Robert; Pourpoint, Timothee L.; Ramachandran, P.V.; Varma, Arvind; Zheng, Yuan

2011-01-01

The Hydrogen Systems Laboratory in a unique partnership between Purdue University's main campus in West Lafayette and the Calumet campus was established and its capabilities were enhanced towards technology demonstrators. The laboratory engaged in basic research in hydrogen production and storage and initiated engineering systems research with performance goals established as per the USDOE Hydrogen, Fuel Cells, and Infrastructure Technologies Program. In the chemical storage and recycling part of the project, we worked towards maximum recycling yield via novel chemical selection and novel recycling pathways. With the basic potential of a large hydrogen yield from AB, we used it as an example chemical but have also discovered its limitations. Further, we discovered alternate storage chemicals that appear to have advantages over AB. We improved the slurry hydrolysis approach by using advanced slurry/solution mixing techniques. We demonstrated vehicle scale aqueous and non-aqueous slurry reactors to address various engineering issues in on-board chemical hydrogen storage systems. We measured the thermal properties of raw and spent AB. Further, we conducted experiments to determine reaction mechanisms and kinetics of hydrothermolysis in hydride-rich solutions and slurries. We also developed a continuous flow reactor and a laboratory scale fuel cell power generation system. The biological hydrogen production work summarized as Task 4.0 below, included investigating optimal hydrogen production cultures for different substrates, reducing the water content in the substrate, and integrating results from vacuum tube solar collector based pre and post processing tests into an enhanced energy system model. An automated testing device was used to finalize optimal hydrogen production conditions using statistical procedures. A 3 L commercial fermentor (New Brunswick, BioFlo 115) was used to finalize testing of larger samples and to consider issues related to scale up. Efforts

Study on construction method of concrete in the underground research laboratory

International Nuclear Information System (INIS)

Iriya, Keshiro; Mikami, Tetsuji; Yasuoka, Tetsuji; Uegaki, Yoshiaki

2001-05-01

Although there are several types in low alkalinity cements, highly fly ash contained silicafume cement (HFSC) has been studied in JNC. It is demonstrated that pH of pore water of the cement indicates below 10.5 as results of other TRU study. However although chemical properties and basic mechanical behavior are well understood, workability so on in constructing is little investigated. Since the underground research laboratory plays a important role in investigating constructing technology, HFSC will be adopted for supporting rock cavern so on. It is required that workability of low alkalinity cements should be assessed. Major performance of workability in tunnel construction in rock will be investigated and R and D planning will be done toward the laboratory construction. Conclusion obtained in this study is described as followings. 1) As results of laboratory test, HFSC and LHHPC developed by AECL fulfil the requirements of shotcrete using by hardening accelerator with calcium-salpho-aluminate. It is concluded that HFSC and LHHPC can be applied for shotcrete. 2) The experiment upon corrosion of re-bars by facing saline water at a offshore is planned. 3) It is noted that pH decreases significantly with rise of silicafume content and that silicafume should be used as much as OPC. 4) It is investigated where the low alkalinity cement should be applied in a actual radio waste repository and R and D program in the laboratory is planned. (author)

Life sciences payload definition and integration study. Volume 3: Preliminary equipment item specification catalog for the carry-on laboratories. [for Spacelab

Science.gov (United States)

1974-01-01

All general purpose equipment items contained in the final carry-on laboratory (COL) design concepts are described in terms of specific requirements identified for COL use, hardware status, and technical parameters such as weight, volume, power, range, and precision. Estimated costs for each item are given, along with projected development times.

Current practice in laboratory diagnostics of autoimmune diseases in Croatia. 
Survey of the Working group for laboratory diagnostics of autoimmune diseases of the Croatian Society of Medical Biochemistry and Laboratory Medicine.

Science.gov (United States)

Kuna, Andrea Tešija; Đerek, Lovorka; Kozmar, Ana; Drvar, Vedrana

2016-10-15

With the trend of increasing incidence of autoimmune diseases, laboratories are faced with exponential growth of the requests for tests relating the diagnosis of these diseases. Unfortunately, the lack of laboratory personnel experienced in this specific discipline of laboratory diagnostic, as well as an unawareness of a method limitation often results in confusion for clinicians. The aim was to gain insight into number and type of Croatian laboratories that perform humoral diagnostics with the final goal to improve and harmonize laboratory diagnostics of autoimmune diseases in Croatia. In order to get insight into current laboratory practice two questionnaires, consisting of 42 questions in total, were created. Surveys were conducted using SurveyMonkey application and were sent to 88 medical biochemistry laboratories in Croatia for the first survey. Out of 33 laboratories that declared to perform diagnostic from the scope, 19 were selected for the second survey based on the tests they pleaded to perform. The survey comprised questions regarding autoantibody hallmarks of systemic autoimmune diseases while regarding organ-specific autoimmune diseases was limited to diseases of liver, gastrointestinal and nervous system. Response rate was high with 80 / 88 (91%) laboratories which answered the first questionnaire, and 19 / 19 (1.0) for the second questionnaire. Obtained results of surveys indicate high heterogeneity in the performance of autoantibody testing among laboratories in Croatia. Results indicate the need of creating recommendations and algorithms in order to harmonize the approach to laboratory diagnostics of autoimmune diseases in Croatia.

Assistance to high schools: A mobile Nuclear Physics Laboratory. Final report, 1991--1992 activities

International Nuclear Information System (INIS)

Kerlin, T.W.; Dean, C.H.

1992-01-01

The Nuclear Engineering Department of the University of Tennessee was awarded a grant from DOE to expand and improve a program of assisting high school physics teachers in their coverage of nuclear physics. Nuclear physics has routinely been handled poorly in high school classes. There are several reasons for this: nuclear physics is usually near the end of high school physics texts and teachers often fail to get to it, many teachers are unfamiliar with nuclear physics and are reluctant to cover it, and laboratories are a problem because equipment is expensive, teachers often do not know how to use the equipment and schools often do not want to store radioactive sources. The assistance program encourages teachers to cover nuclear physics and overcomes the problems associated with laboratories

FEBEX II Project Final report on thermo-hydro-mechanical laboratory tests

International Nuclear Information System (INIS)

Lloret, A.; Romero, E.; Villar, M. V.

2004-01-01

The results of the thermo-hydro-mechanical (THM) study of the FEBEX bentonite performed during FEBEX II are presented. The laboratory test program continued in part with the works carried out during FEBEX I, particularly in activities related to tests aimed to the calibration of the models, the acquisition of parameters by back-analysis and the improvement of the knowledge on the behaviour of expansive clays. But the program has also included tests on new areas: investigations about the influence of the microstructure changes in bentonite, of temperature and of the solute concentration on the behaviour of clay. Besides, several tests were proposed in order to understand the unexpected behaviour observed in the mock-up test, towards the end of year 2. Temperature effects on water retention curves in confined and unconfined conditions were determined, and swelling pressure, hydraulic conductivity and swelling and consolidation strains as a function of temperature were successfully measured. Different experimental techniques and equipments were developed to study thermal induced changes under partially saturated states, covering a wide range of suctions. FEBEX bentonite remains suitable as a sealing material in HLW repositories (from the hydro- mechanical point of view) for temperatures of up to 80 C, as it keeps its high water retention capacity, low permeability and self-healing ability. The extrapolation of results points out to the preservation of properties for at least up to 100 C. Mercury intrusion porosimetry and environmental scanning electron microscopy provided promising results in order to characterise the bentonite microstructure and to give information about the mechanisms influencing pore size distribution changes on high active clays. The use of digital imaging techniques allowed verifying that at micro-scale level, where chemical phenomena prevail, strains are almost reversible as it is considered in the two-level elasto-plastic models. The swelling

FEBEX II Project Final report on thermo-hydro-mechanical laboratory tests

Energy Technology Data Exchange (ETDEWEB)

Lloret, A.; Romero, E.; Villar, M. V.

2004-07-01

The results of the thermo-hydro-mechanical (THM) study of the FEBEX bentonite performed during FEBEX II are presented. The laboratory test program continued in part with the works carried out during FEBEX I, particularly in activities related to tests aimed to the calibration of the models, the acquisition of parameters by back-analysis and the improvement of the knowledge on the behaviour of expansive clays. But the program has also included tests on new areas: investigations about the influence of the microstructure changes in bentonite, of temperature and of the solute concentration on the behaviour of clay. Besides, several tests were proposed in order to understand the unexpected behaviour observed in the mock-up test, towards the end of year 2. Temperature effects on water retention curves in confined and unconfined conditions were determined, and swelling pressure, hydraulic conductivity and swelling and consolidation strains as a function of temperature were successfully measured. Different experimental techniques and equipments were developed to study thermal induced changes under partially saturated states, covering a wide range of suctions. FEBEX bentonite remains suitable as a sealing material in HLW repositories (from the hydro- mechanical point of view) for temperatures of up to 80 C, as it keeps its high water retention capacity, low permeability and self-healing ability. The extrapolation of results points out to the preservation of properties for at least up to 100 C. Mercury intrusion porosimetry and environmental scanning electron microscopy provided promising results in order to characterise the bentonite microstructure and to give information about the mechanisms influencing pore size distribution changes on high active clays. The use of digital imaging techniques allowed verifying that at micro-scale level, where chemical phenomena prevail, strains are almost reversible as it is considered in the two-level elasto-plastic models. The swelling

Clinical laboratory: bigger is not always better.

Science.gov (United States)

Plebani, Mario

2018-06-27

Laboratory services around the world are undergoing substantial consolidation and changes through mechanisms ranging from mergers, acquisitions and outsourcing, primarily based on expectations to improve efficiency, increasing volumes and reducing the cost per test. However, the relationship between volume and costs is not linear and numerous variables influence the end cost per test. In particular, the relationship between volumes and costs does not span the entire platter of clinical laboratories: high costs are associated with low volumes up to a threshold of 1 million test per year. Over this threshold, there is no linear association between volumes and costs, as laboratory organization rather than test volume more significantly affects the final costs. Currently, data on laboratory errors and associated diagnostic errors and risk for patient harm emphasize the need for a paradigmatic shift: from a focus on volumes and efficiency to a patient-centered vision restoring the nature of laboratory services as an integral part of the diagnostic and therapy process. Process and outcome quality indicators are effective tools to measure and improve laboratory services, by stimulating a competition based on intra- and extra-analytical performance specifications, intermediate outcomes and customer satisfaction. Rather than competing with economic value, clinical laboratories should adopt a strategy based on a set of harmonized quality indicators and performance specifications, active laboratory stewardship, and improved patient safety.

Laboratory studies of radionuclide transport in fractured Climax granite

International Nuclear Information System (INIS)

Failor, R.; Isherwood, D.; Raber, E.; Vandergraaf, T.

1982-06-01

This report documents our laboratory studies of radionuclide transport in fractured granite cores. To simulate natural conditions, our laboratory studies used naturally fractured cores and natural ground water from the Climax Granite Stock at the Nevada Test Site. For comparison, additional tests used artificially fractured granite cores or distilled water. Relative to the flow of tritiated water, 85 Sr and /sup 95m/Tc showed little or no retardation, whereas 137 Cs was retarded. After the transport runs the cores retained varying amounts of the injected radionuclides along the fracture. Autoradiography revealed some correlation between sorption and the fracture fill material. Strontium and cesium retention increased when the change was made from natural ground water to distilled water. Artificial fractures retained less 137 Cs than most natural fractures. Estimated fracture apertures from 18 to 60 μm and hydraulic conductivities from 1.7 to 26 x 10 -3 m/s were calculated from the core measurements

Plant systems/components modularization study. Final report

International Nuclear Information System (INIS)

1977-07-01

The final results are summarized of a Plant Systems/Components Modularization Study based on Stone and Webster's Pressurized Water Reactor Reference Design. The program has been modified to include evaluation of the most promising areas for modular consideration based on the level of the Sundesert Project engineering design completion and the feasibility of their incorporation into the plant construction effort

Estimating retention in HIV care accounting for patient transfers: A national laboratory cohort study in South Africa.

Science.gov (United States)

Fox, Matthew P; Bor, Jacob; Brennan, Alana T; MacLeod, William B; Maskew, Mhairi; Stevens, Wendy S; Carmona, Sergio

2018-06-01

Systematic reviews have described high rates of attrition in patients with HIV receiving antiretroviral therapy (ART). However, migration and clinical transfer may lead to an overestimation of attrition (death and loss to follow-up). Using a newly linked national laboratory database in South Africa, we assessed national retention in South Africa's national HIV program. Patients receiving care in South Africa's national HIV program are monitored through regular CD4 count and viral load testing. South Africa's National Health Laboratory Service has maintained a database of all public-sector CD4 count and viral load results since 2004. We linked individual laboratory results to patients using probabilistic matching techniques, creating a national HIV cohort. Validation of our approach in comparison to a manually matched dataset showed 9.0% undermatching and 9.5% overmatching. We analyzed data on patients initiating ART in the public sector from April 1, 2004, to December 31, 2006, when ART initiation could be determined based on first viral load among those whose treatment followed guidelines. Attrition occurred on the date of a patient's last observed laboratory measure, allowing patients to exit and reenter care prior to that date. All patients had 6 potential years of follow-up, with an additional 2 years to have a final laboratory measurement to be retained at 6 years. Data were censored at December 31, 2012. We assessed (a) national retention including all laboratory tests regardless of testing facility and (b) initiating facility retention, where laboratory tests at other facilities were ignored. We followed 55,836 patients initiating ART between 2004 and 2006. At ART initiation, median age was 36 years (IQR: 30-43), median CD4 count was 150 cells/mm3 (IQR: 81-230), and 66.7% were female. Six-year initiating clinic retention was 29.1% (95% CI: 28.7%-29.5%). After allowing for transfers, national 6-year retention was 63.3% (95% CI: 62.9%-63.7%). Results differed

First-year Engineering Education with the Creative Electrical Engineering Laboratory

Science.gov (United States)

Tsukamoto, Takehiko; Sugito, Tetsumasa; Ozeki, Osamu; Ushiroda, Sumio

The Department of Electrical and Electronic Engineering in Toyota National College of Technology has put great emphasis on fundamental subjects. We introduced the creative electrical engineering laboratory into the first-year engineering education since 1998. The laboratory concentrates on the practice exercise. The final questionnaire of students showed that our first-year education is very effective to promote students motivation and their scholastic ability in engineering.

Annual report of Laboratory of Nuclear Studies, Osaka University, 1980

International Nuclear Information System (INIS)

1981-01-01

This is the progress report of the research activities in the Laboratory of Nuclear Studies during the period from April, 1980, to March, 1981. The activities were carried out by the OULNS staffs and also by outsiders at the OULNS. In this period, the X-ray astrophysics group, the radiation physics group and the high energy physics group joined the OULNS. The main accelerators in the OULNS are a 110 cm variable energy cyclotron and a 4.7 MeV Van de Graaff machine. The detailed experimental studies on inbeam e-gamma spectroscopy and beta-decay were carried out at two accelerator laboratories. The radiochemistry facility and a mass spectrometer were fully used. The research activities extended to high energy physics by utilizing national facilities, such as a 230 cm cyclotron in the Research Center for Nuclear Physics and a proton synchrotron in the National Laboratory for High Energy Physics. The theoretical studies on elementary particles and nuclear physics were carried out also. It is important that the facilities in the OULNS were used by the outsiders in Osaka University, such as solid state physics group and particle-induced X-ray group. The activities of the divisions of cyclotron, Van de Graaff, high energy physics, accelerator development and nuclear instrumentation, mass spectroscopy, radioisotope, solid state and theoretical physics are reported. (Kako, I.)

Decontamination and decommissioning of the SPERT-I Reactor Building at the Idaho National Engineering Laboratory. Final report

International Nuclear Information System (INIS)

Dolenc, M.R.

1986-02-01

This final report documents the decontamination and decommissioning of the SPERT-I Reactor Building. This 20- by 40-ft galvanized steel building was dismantled; and the resultant contaminated sludge, liquid, and carbon steel were disposed of at the Radioactive Waste Management Complex of the Idaho National Engineering Laboratory. This report presents the results of the characterization, decision analysis, planning, and decommissioning of the facility. The total cost of these activities was $139,500. Of this total, $103,500 was required for decommissioning operations. (This latter figure represents a 20% savings over the estimated costs generated during the planning effort.) The objectives of decommissioning this facility were to stabilize the seepage pit area and remove the reactor building. The D and D work was divided into two parts; the seepage pit was decommissioned in 1984, and the reactor building in 1985. The entire area was backfilled with radiologically clean soil, graded, and seeded. Two markers were installed to identify the locations of the pit and reactor building. The only isotopes found in either decommissioning operation were cesium-137 and uranium-235 in very low concentrations. Decommissioning operations of the reactor building were carried out during August 1985. The project generate 297 ft 3 of radioactive waste. No personnel radiation exposure above background was received by D and D workers

'LABNOTE', a laboratory notebook system designed for academic genomics groups.

Science.gov (United States)

Imbert, M C; Nguyen, V K; Granjeaud, S; Nguyen, C; Jordan, B R

1999-01-15

We have developed a relational laboratory database system, adapted to the daily book-keeping needs of laboratories that must keep track of information acquired on hundreds or thousands of clones in an effective and user-friendly fashion. Data, whether final or related to experiments in progress, can be accessed in many different ways, e.g. by clone name, by gene, by experiment or through DNA sequence. Updating, import and export of results is made easier by specially developed tools. This system, in network version, serves several groups in our Institute and (over the Internet) elsewhere, and is instrumental in collaborative studies based on expression profiling. It can be used in many similar situations involving progressiveaccumulation of information on sets of clones or related objects.

[Laboratory medicine in the obligatory postgraduate clinical training system--common clinical training program in the department of laboratory medicine in our prefectural medical university hospital].

Science.gov (United States)

Okamoto, Yasuyuki

2003-04-01

I propose a postgraduate common clinical training program to be provided by the department of laboratory medicine in our prefectural medical university hospital. The program has three purposes: first, mastering basic laboratory tests; second, developing the skills necessary to accurately interpret laboratory data; third, learning specific techniques in the field of laboratory medicine. For the first purpose, it is important that medical trainees perform testing of their own patients at bedside or in the central clinical laboratory. When testing at the central clinical laboratory, instruction by expert laboratory technicians is helpful. The teaching doctors in the department of laboratory medicine are asked to advise the trainees on the interpretation of data. Consultation will be received via interview or e-mail. In addition, the trainees can participate in various conferences, seminars, and meetings held at the central clinical laboratory. Finally, in order to learn specific techniques in the field of laboratory medicine, several special courses lasting a few months will be prepared. I think this program should be closely linked to the training program in internal medicine.

A study of 6S workplace improvement in Ergonomic Laboratory

Science.gov (United States)

Sari, AD; Suryoputro, MR; Rahmillah, FI

2017-12-01

This article discusses 6S implementation in Ergonomic Laboratory, Department of Industrial Engineering, Islamic University of Indonesia. This research is improvement project of 5S implementation in Ergonomic laboratory. Referring to the 5S implementation of the previous year, there have been improvements from environmental conditions or a more organized workplace however there is still a lack of safety aspects. There are several safeties problems such as equipment arrangement, potential hazards of room dividers that cause injury several times, placement of fire extinguisher, no evacuation path and assembly point in case of fire, as well as expired hydrant condition and lack of awareness of stakeholders related to safety. Therefore, this study aims to apply the 6S kaizen method to the Ergonomic laboratory to facilitate the work process, reduce waste, improve work safety and improve staff performance. Based on the score 6S assessment increased audit results by 32 points, before implementation is 75 point while after implementation is 107 point. This has implications for better use for mitigate people in laboratory area, save time when looking for tools and materials, safe workplace, as well as improving the culture and spirit of ‘6S’ on staff due to better and safetier working environment.

Site study plan for routine laboratory rock mechanics, Deaf Smith County Site, Texas: Revision 1

International Nuclear Information System (INIS)

1987-12-01

This Site Study Plan for Routine Laboratory Rock Mechanics describes routine laboratory testing to be conducted on rock samples collected as part of the characterization of the Deaf Smith County site, Texas. This study plan describes the early laboratory testing. Additional testing may be required and the type and scope of testing will be dependent upon the results of the early testing. This study provides for measurements of index, hydrological, mechanical, and chemical properties with tests which are standardized and used widely in geotechnical investigations. Another Site Study Plan for Nonroutine Laboratory Rock Mechanics describes laboratory testing of samples from the site to determine mechanical, thermomechanical, and thermal properties by less widely used methods, many of which have been developed specifically for characterization of the site. Data from laboratory tests will be used for characterization of rock strata, design of shafts and underground facilities, and modeling of repository behavior in support of resolution of both preclosure and postclosure issues. A tentative testing schedule and milestone log are given. A quality assurance program will be utilized to assure that activities affecting quality are performed correctly and that appropriate documentation is maintained. 18 refs., 8 figs., 3 tabs

Laboratory for Extraterrestrial Physics

Science.gov (United States)

Vondrak, Richard R. (Technical Monitor)

2001-01-01

The NASA Goddard Space Flight Center (GSFC) Laboratory for Extraterrestrial Physics (LEP) performs experimental and theoretical research on the heliosphere, the interstellar medium, and the magnetospheres and upper atmospheres of the planets, including Earth. LEP space scientists investigate the structure and dynamics of the magnetospheres of the planets including Earth. Their research programs encompass the magnetic fields intrinsic to many planetary bodies as well as their charged-particle environments and plasma-wave emissions. The LEP also conducts research into the nature of planetary ionospheres and their coupling to both the upper atmospheres and their magnetospheres. Finally, the LEP carries out a broad-based research program in heliospheric physics covering the origins of the solar wind, its propagation outward through the solar system all the way to its termination where it encounters the local interstellar medium. Special emphasis is placed on the study of solar coronal mass ejections (CME's), shock waves, and the structure and properties of the fast and slow solar wind. LEP planetary scientists study the chemistry and physics of planetary stratospheres and tropospheres and of solar system bodies including meteorites, asteroids, comets, and planets. The LEP conducts a focused program in astronomy, particularly in the infrared and in short as well as very long radio wavelengths. We also perform an extensive program of laboratory research, including spectroscopy and physical chemistry related to astronomical objects. The Laboratory proposes, develops, fabricates, and integrates experiments on Earth-orbiting, planetary, and heliospheric spacecraft to measure the characteristics of planetary atmospheres and magnetic fields, and electromagnetic fields and plasmas in space. We design and develop spectrometric instrumentation for continuum and spectral line observations in the x-ray, gamma-ray, infrared, and radio regimes; these are flown on spacecraft to study

Safety research experiment facilities, Idaho National Engineering Laboratory, Idaho. Final environmental impact statement

International Nuclear Information System (INIS)

Liverman, J.L.

1977-09-01

This environmental statement was prepared for the Safety Research Experiment Facilities (SAREF) Project. The purpose of the proposed project is to modify some existing facilities and provide a new test facility at the Idaho National Engineering Laboratory (INEL) for conducting fast breeder reactor (FBR) safety experiments. The SAREF Project proposal has been developed after an extensive study which identified the FBR safety research needs requiring in-reactor experiments and which evaluated the capability of various existing and new facilities to meet these needs. The proposed facilities provide for the in-reactor testing of large bundles of prototypical FBR fuel elements under a wide variety of conditions, ranging from those abnormal operating conditions which might be expected to occur during the life of an FBR power plant to the extremely low probability, hypothetical accidents used in the evaluation of some design options and in the assessment of the long-term potential risk associated with wide-acale deployment of the FBR

Laboratory studies of radionuclide migration in tuff

International Nuclear Information System (INIS)

Rundberg, R.S.; Mitchell, A.J.; Ott, M.A.; Thompson, J.L.; Triay, I.R.

1989-01-01

The movement of selected radionuclides has been observed in crushed tuff, intact tuff, and fractured tuff columns. Retardation factors and dispersivities were determined from the elution profiles. Retardation factors have been compared with those predicted on the basis of batch sorption studies. This comparison forms a basis for either validating distribution coefficients or providing evidence of speciation, including colloid formation. Dispersivities measured as a function of velocity provide a means of determining the effect of sorption kinetics or mass transfer on radionuclide migration. Dispersion is also being studied in the context of scaling symmetry to develop a basis for extrapolating from the laboratory scale to the field. 21 refs., 6 figs., 2 tabs

GeoBrain Computational Cyber-laboratory for Earth Science Studies

Science.gov (United States)

Deng, M.; di, L.

2009-12-01

Computational approaches (e.g., computer-based data visualization, analysis and modeling) are critical for conducting increasingly data-intensive Earth science (ES) studies to understand functions and changes of the Earth system. However, currently Earth scientists, educators, and students have met two major barriers that prevent them from being effectively using computational approaches in their learning, research and application activities. The two barriers are: 1) difficulties in finding, obtaining, and using multi-source ES data; and 2) lack of analytic functions and computing resources (e.g., analysis software, computing models, and high performance computing systems) to analyze the data. Taking advantages of recent advances in cyberinfrastructure, Web service, and geospatial interoperability technologies, GeoBrain, a project funded by NASA, has developed a prototype computational cyber-laboratory to effectively remove the two barriers. The cyber-laboratory makes ES data and computational resources at large organizations in distributed locations available to and easily usable by the Earth science community through 1) enabling seamless discovery, access and retrieval of distributed data, 2) federating and enhancing data discovery with a catalogue federation service and a semantically-augmented catalogue service, 3) customizing data access and retrieval at user request with interoperable, personalized, and on-demand data access and services, 4) automating or semi-automating multi-source geospatial data integration, 5) developing a large number of analytic functions as value-added, interoperable, and dynamically chainable geospatial Web services and deploying them in high-performance computing facilities, 6) enabling the online geospatial process modeling and execution, and 7) building a user-friendly extensible web portal for users to access the cyber-laboratory resources. Users can interactively discover the needed data and perform on-demand data analysis and

Strategies for laboratory cost containment and for pathologist shortage: centralised pathology laboratories with microwave-stimulated histoprocessing and telepathology.

Science.gov (United States)

Leong, Anthony S Y; Leong, F Joel W M

2005-02-01

The imposition of laboratory cost containment, often from external forces, dictates the necessity to develop strategies to meet laboratory cost savings. In addition, the national and worldwide shortage of anatomical pathologists makes it imperative to examine our current practice and laboratory set-ups. Some of the strategies employed in other areas of pathology and laboratory medicine include improvements in staff productivity and the adoption of technological developments that reduce manual intervention. However, such opportunities in anatomical pathology are few and far between. Centralisation has been an effective approach in bringing economies of scale, the adoption of 'best practices' and the consolidation of pathologists, but this has not been possible in anatomical pathology because conventional histoprocessing takes a minimum of 14 hours and clinical turnaround time requirements necessitate that the laboratory and pathologist be in proximity and on site. While centralisation of laboratories for clinical chemistry, haematology and even microbiology has been successful in Australia and other countries, the essential requirements for anatomical pathology laboratories are different. In addition to efficient synchronised courier networks, a method of ultra-rapid tissue processing and some expedient system of returning the prepared tissue sections to the remote laboratory are essential to maintain the turnaround times mandatory for optimal clinical management. The advent of microwave-stimulated tissue processing that can be completed in 30-60 minutes and the immediate availability of compressed digital images of entire tissue sections via telepathology completes the final components of the equation necessary for making centralised anatomical pathology laboratories a reality.

Atmospheric cloud physics laboratory project study

Science.gov (United States)

Schultz, W. E.; Stephen, L. A.; Usher, L. H.

1976-01-01

Engineering studies were performed for the Zero-G Cloud Physics Experiment liquid cooling and air pressure control systems. A total of four concepts for the liquid cooling system was evaluated, two of which were found to closely approach the systems requirements. Thermal insulation requirements, system hardware, and control sensor locations were established. The reservoir sizes and initial temperatures were defined as well as system power requirements. In the study of the pressure control system, fluid analyses by the Atmospheric Cloud Physics Laboratory were performed to determine flow characteristics of various orifice sizes, vacuum pump adequacy, and control systems performance. System parameters predicted in these analyses as a function of time include the following for various orifice sizes: (1) chamber and vacuum pump mass flow rates, (2) the number of valve openings or closures, (3) the maximum cloud chamber pressure deviation from the allowable, and (4) cloud chamber and accumulator pressure.

Comparison of microbiological diagnosis of urinary tract infection in young children by routine health service laboratories and a research laboratory: Diagnostic cohort study.

Directory of Open Access Journals (Sweden)

Kate Birnie

Full Text Available To compare the validity of diagnosis of urinary tract infection (UTI through urine culture between samples processed in routine health service laboratories and those processed in a research laboratory.We conducted a prospective diagnostic cohort study in 4808 acutely ill children aged <5 years attending UK primary health care. UTI, defined as pure/predominant growth ≥105 CFU/mL of a uropathogen (the reference standard, was diagnosed at routine health service laboratories and a central research laboratory by culture of urine samples. We calculated areas under the receiver-operator curve (AUC for UTI predicted by pre-specified symptoms, signs and dipstick test results (the "index test", separately according to whether samples were obtained by clean catch or nappy (diaper pads.251 (5.2% and 88 (1.8% children were classified as UTI positive by health service and research laboratories respectively. Agreement between laboratories was moderate (kappa = 0.36; 95% confidence interval [CI] 0.29, 0.43, and better for clean catch (0.54; 0.45, 0.63 than nappy pad samples (0.20; 0.12, 0.28. In clean catch samples, the AUC was lower for health service laboratories (AUC = 0.75; 95% CI 0.69, 0.80 than the research laboratory (0.86; 0.79, 0.92. Values of AUC were lower in nappy pad samples (0.65 [0.61, 0.70] and 0.79 [0.70, 0.88] for health service and research laboratory positivity, respectively than clean catch samples.The agreement of microbiological diagnosis of UTI comparing routine health service laboratories with a research laboratory was moderate for clean catch samples and poor for nappy pad samples and reliability is lower for nappy pad than for clean catch samples. Positive results from the research laboratory appear more likely to reflect real UTIs than those from routine health service laboratories, many of which (particularly from nappy pad samples could be due to contamination. Health service laboratories should consider adopting procedures used

Comparison of microbiological diagnosis of urinary tract infection in young children by routine health service laboratories and a research laboratory: Diagnostic cohort study

Science.gov (United States)

Birnie, Kate; Hay, Alastair D.; Wootton, Mandy; Howe, Robin; MacGowan, Alasdair; Whiting, Penny; Lawton, Michael; Delaney, Brendan; Downing, Harriet; Dudley, Jan; Hollingworth, William; Lisles, Catherine; Little, Paul; O’Brien, Kathryn; Pickles, Timothy; Rumsby, Kate; Thomas-Jones, Emma; Van der Voort, Judith; Waldron, Cherry-Ann; Harman, Kim; Hood, Kerenza; Butler, Christopher C.; Sterne, Jonathan A. C.

2017-01-01

Objectives To compare the validity of diagnosis of urinary tract infection (UTI) through urine culture between samples processed in routine health service laboratories and those processed in a research laboratory. Population and methods We conducted a prospective diagnostic cohort study in 4808 acutely ill children aged <5 years attending UK primary health care. UTI, defined as pure/predominant growth ≥105 CFU/mL of a uropathogen (the reference standard), was diagnosed at routine health service laboratories and a central research laboratory by culture of urine samples. We calculated areas under the receiver-operator curve (AUC) for UTI predicted by pre-specified symptoms, signs and dipstick test results (the “index test”), separately according to whether samples were obtained by clean catch or nappy (diaper) pads. Results 251 (5.2%) and 88 (1.8%) children were classified as UTI positive by health service and research laboratories respectively. Agreement between laboratories was moderate (kappa = 0.36; 95% confidence interval [CI] 0.29, 0.43), and better for clean catch (0.54; 0.45, 0.63) than nappy pad samples (0.20; 0.12, 0.28). In clean catch samples, the AUC was lower for health service laboratories (AUC = 0.75; 95% CI 0.69, 0.80) than the research laboratory (0.86; 0.79, 0.92). Values of AUC were lower in nappy pad samples (0.65 [0.61, 0.70] and 0.79 [0.70, 0.88] for health service and research laboratory positivity, respectively) than clean catch samples. Conclusions The agreement of microbiological diagnosis of UTI comparing routine health service laboratories with a research laboratory was moderate for clean catch samples and poor for nappy pad samples and reliability is lower for nappy pad than for clean catch samples. Positive results from the research laboratory appear more likely to reflect real UTIs than those from routine health service laboratories, many of which (particularly from nappy pad samples) could be due to contamination. Health service

ESTABLISHMENT OF AN ENVIRONMENTAL CONTROL TECHNOLOGY LABORATORY WITH A CIRCULATING FLUIDIZED-BED COMBUSTION SYSTEM

Energy Technology Data Exchange (ETDEWEB)

Wei-Ping Pan; Andy Wu; John T. Riley

2004-10-30

This report is to present the progress made on the project ''Establishment of an Environmental Control Technology Laboratory (ECTL) with a Circulating Fluidized-Bed Combustion (CFBC) System'' during the period July 1, 2004 through September 30, 2004. The following tasks have been completed. First, renovation of the new Combustion Laboratory and the construction of the Circulating Fluidized-Bed (CFB) Combustor Building have started. Second, the design if the component parts of the CFBC system have been reviewed and finalized so that the drawings may be released to the manufacturers during the next quarter. Third, the experiments for solid waste (chicken litter) incineration have been conducted using a Thermogravimetric Analyzer (TGA). This is in preparation for testing in the simulated fluidized-bed combustor. The experimental results from this study are presented in this report. Finally, the proposed work for the next quarter has been outlined in this report.

Aespoe Hard Rock Laboratory. Annual Report 2006

Energy Technology Data Exchange (ETDEWEB)

NONE

2006-06-15

The Aespoe Hard Rock Laboratory (HRL) is an important part of SKB's work with the design and construction of a deep geological repository for the final disposal of spent nuclear fuel. Aespoe HRL is located in the Simpevarp area in the municipality of Oskarshamn. One of the fundamental reasons behind SKB's decision to construct an underground laboratory was to create opportunities for research, development and demonstration in a realistic and undisturbed rock environment down to repository depth. The underground part of the laboratory consists of a tunnel from the Simpevarp peninsula to the southern part of Aespoe where the tunnel continues in a spiral down to a depth of 460 m. Aespoe HRL has been in operation since 1995 and considerable international interest has been shown in its research, as well as in the development and demonstration tasks. The work performed at Aespoe HRL during 2006 is in this report described in six chapters: Geo-science - experiments, analysis and modelling to increase the knowledge of the surrounding rock; Natural barriers - experiments, analysis and modelling to increase the knowledge of the repository barriers under natural conditions; Engineered barriers - demonstration of technology for and function of important engineered parts of the repository barrier system; Aespoe facility - operation, maintenance, data management, monitoring, public relations etc; Environmental research; and finally, International co-operation.

Aespoe Hard Rock Laboratory. Annual Report 2006

International Nuclear Information System (INIS)

2006-06-01

The Aespoe Hard Rock Laboratory (HRL) is an important part of SKB's work with the design and construction of a deep geological repository for the final disposal of spent nuclear fuel. Aespoe HRL is located in the Simpevarp area in the municipality of Oskarshamn. One of the fundamental reasons behind SKB's decision to construct an underground laboratory was to create opportunities for research, development and demonstration in a realistic and undisturbed rock environment down to repository depth. The underground part of the laboratory consists of a tunnel from the Simpevarp peninsula to the southern part of Aespoe where the tunnel continues in a spiral down to a depth of 460 m. Aespoe HRL has been in operation since 1995 and considerable international interest has been shown in its research, as well as in the development and demonstration tasks. The work performed at Aespoe HRL during 2006 is in this report described in six chapters: Geo-science - experiments, analysis and modelling to increase the knowledge of the surrounding rock; Natural barriers - experiments, analysis and modelling to increase the knowledge of the repository barriers under natural conditions; Engineered barriers - demonstration of technology for and function of important engineered parts of the repository barrier system; Aespoe facility - operation, maintenance, data management, monitoring, public relations etc; Environmental research; and finally, International co-operation

Virtual Laboratory "vs." Traditional Laboratory: Which Is More Effective for Teaching Electrochemistry?

Science.gov (United States)

Hawkins, Ian; Phelps, Amy J.

2013-01-01

The use of virtual laboratories has become an increasing issue regarding science laboratories due to the increasing cost of hands-on laboratories, and the increase in distance education. Recent studies have looked at the use of virtual tools for laboratory to be used as supplements to the regular hands-on laboratories but many virtual tools have…

Beat-wave accelerator studies at the Rutherford Appleton Laboratory

International Nuclear Information System (INIS)

Lawson, J.D.

1985-01-01

The study carried out in 1982-83 at the Rutherford Appleton Laboratory to examine how one might use the beat-wave principle to construct a useful high energy accelerator is reviewed, and comments are made on later developments. A number of problems are evident to which solutions cannot at present be foreseen. (author)

The 1993 QUASIMEME laboratory-performance study: chlorobiphenyls in fish oil and standard solutions

NARCIS (Netherlands)

Wells, D.E.; Boer, de J.

1994-01-01

A laboratory-performance study has been undertaken to improve the measurement of chlorobiphenyls in marine biota as part of the QUASIMEME (EU - Measurement and Testing) project. Fifty-two laboratories were invited to participate, of which 47 returned data on nine congeners in iso-octane solution and

Annual report of Laboratory of Nuclear Studies, Osaka University, for fiscal 1979

International Nuclear Information System (INIS)

1980-01-01

This annual report presents the research activities carried out by the members of the Laboratory and the users of the facilities. The major facilities of the Laboratory are a 110 cm variable energy cyclotron and a 4.7 MeV Van de Graaff. The cyclotron division has made extensive studies on nuclear physics, such as the pre-equilibrium process of neutron emission, inelastic proton scattering, He-3 induced reactions, and polarization experiments. The Van de Graaff division reports about the works on hyperfine interaction, mirror beta-decay, heavy element ion source, and nuclear spin alignment. Model magnet study on the future project has also been developed at the Laboratory. Other divisions of the Laboratory are the mass spectroscopy division, the radioisotope division, and the theoretical physics division. The works of the mass spectroscopy division concern the on-line mass separation of radioisotopes, the field desorption of mass spectra, and instrumentation. The works of the radioisotope division spread widely on the field of nuclear chemistry. At the end of this report, various works, which have been made by the theoretical physics division, are introduced. (Kato, T.)

Final Technical Report: Magnetic Reconnection in High-Energy Laser-Produced Plasmas

Energy Technology Data Exchange (ETDEWEB)

Germaschewski, Kai [Univ. of New Hampshire, Durham, NH (United States); Fox, William [Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States); Bhattacharjee, Amitava [Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States)

2017-04-06

This report describes the final results from the DOE Grant DE-SC0007168, “Fast Magnetic Reconnection in HED Laser-Produced Plasmas.” The recent generation of laboratory high-energy-density physics facilities has opened significant physics opportunities for experimentally modeling astrophysical plasmas. The goal of this proposal is to use these new tools to study fundamental problems in plasma physics and plasma astrophysics. Fundamental topics in this area involve study of the generation, amplification, and fate of magnetic fields, which are observed to pervade the plasma universe and govern its evolution. This project combined experiments at DOE laser facilities with kinetic plasma simulation to study these processes. The primary original goal of the project was to study magnetic reconnection using a new experimental platform, colliding magnetized laser-produced plasmas. However through a series of fortuitous discoveries, the work broadened out to allow significant advancement on multiple topics in laboratory astrophysics, including magnetic reconnection, Weibel instability, and collisionless shocks.

How do laboratory technicians perceive their role in tuberculosis diagnostic process: a cross-sectional study among laboratory technicians in health centers of Central Java Province, Indonesia

Directory of Open Access Journals (Sweden)

Widjanarko B

2016-09-01

Full Text Available Bagoes Widjanarko,1 Dyah Anantalia Widyastari,2 Martini Martini,3 Praba Ginandjar3 1Department of Health Education and Behavior Sciences, Faculty of Public Health, Diponegoro University, Semarang, Indonesia; 2Institute for Population and Social Research, Mahidol University, Salaya, Thailand; 3Department of Epidemiology, Faculty of Public Health, Diponegoro University, Semarang, Indonesia Purpose: Detection of acid-fast bacilli in respiratory specimens serves as an initial pulmonary tuberculosis (TB diagnosis. Laboratories are the essential and fundamental part of all health systems. This study aimed to describe how laboratory technicians perceived their own self and work. This included perceived self-efficacy, perceived role, perceived equipment availability, perceived procedures, perceived reward and job, and perceived benefit of health education, as well as level of knowledge and attitudes related to work performance of laboratory technicians.Methods: This was a cross-sectional quantitative study involving 120 laboratory technicians conducted in Central Java. Interviews and observation were conducted to measure performance and work-related variables.Results: Among 120 laboratory technicians, 43.3% showed fairly good performance. They complied with 50%–75% of all procedures, including sputum collection, laboratory tools utilization, sputum smearing, staining, smear examination, grading of results, and universal precaution practice. Perceived role, perceived self-efficacy, and knowledge of laboratory procedures were significantly correlated to performance, besides education and years of working as a laboratory technician. Perceived equipment availability was also significantly correlated to performance after the education variable was controlled.Conclusion: Most of the laboratory technicians believed that they have an important role in TB patients’ treatment and should display proper self-efficacy in performing laboratory activities. The

How do laboratory technicians perceive their role in the tuberculosis diagnostic process? A cross-sectional study among laboratory technicians in health centers of Central Java Province, Indonesia.

Science.gov (United States)

Widjanarko, Bagoes; Widyastari, Dyah Anantalia; Martini, Martini; Ginandjar, Praba

2016-01-01

Detection of acid-fast bacilli in respiratory specimens serves as an initial pulmonary tuberculosis (TB) diagnosis. Laboratories are the essential and fundamental part of all health systems. This study aimed to describe how laboratory technicians perceived their own self and work. This included perceived self-efficacy, perceived role, perceived equipment availability, perceived procedures, perceived reward and job, and perceived benefit of health education, as well as level of knowledge and attitudes related to work performance of laboratory technicians. This was a cross-sectional quantitative study involving 120 laboratory technicians conducted in Central Java. Interviews and observation were conducted to measure performance and work-related variables. Among 120 laboratory technicians, 43.3% showed fairly good performance. They complied with 50%-75% of all procedures, including sputum collection, laboratory tools utilization, sputum smearing, staining, smear examination, grading of results, and universal precaution practice. Perceived role, perceived self-efficacy, and knowledge of laboratory procedures were significantly correlated to performance, besides education and years of working as a laboratory technician. Perceived equipment availability was also significantly correlated to performance after the education variable was controlled. Most of the laboratory technicians believed that they have an important role in TB patients' treatment and should display proper self-efficacy in performing laboratory activities. The result may serve as a basic consideration to develop a policy for enhancing motivation of laboratory technicians in order to improve the TB control program.

Study on construction method of concrete in the underground research laboratory. 4

International Nuclear Information System (INIS)

Iriya, Keishiro; Tajima, Takatoshi; Noda, Masaru

2004-02-01

Low alkaline cement is planned to use in construction of Horonobe Underground Research Center as one of in situ experiments. These experiments will be carried out in a part of the vertical shafts and horizontal excavated tunnels. The problems in actual using should be solved and improved until starting construction. This study has been carried out in order to improve the HFSC taking the Horonobe environment into account. Model analysis and preliminary laboratory experiment on hyper alkaline alteration of bentonite and rock have been carried out. And a long term permeability experiment on procedure. (author)or the superfluous exposure dose prevention in IVRbased on results of pH measuring for 546 days and geo-chemical code. Open data and undefined reaction were pointed out in order to accomplish the model on low alkalinity cement with high pozollan content. The effects on fresh concrete properties and harden concrete due to changing properties of fly ash were investigated. Experimental basic planning in situ test of low alkaline cement in Horonobe are proposed. And finally, procedure of improvement HFSC in Horonobe construction are investigated and proposed. It is concluded that HFSC can be applied for construction work of Horonobe underground research center. (author)

222-S LABORATORY FUME HOOD TESTING STUDY

International Nuclear Information System (INIS)

RUELAS, B.H.

2007-01-01

The 222-S Laboratory contains 155 active fume hoods that are used to support analytical work with radioactive and/or toxic materials. The performance of a fume hood was brought into question after employees detected odors in the work area while mixing chemicals within the subject fume hood. Following the event, testing of the fume hood was conducted to assess the performance of the fume hood. Based on observations from the testing, it was deemed appropriate to conduct performance evaluations of other fume hoods within the laboratory

Recent advances in the designing and the equipment of high activity laboratories

International Nuclear Information System (INIS)

Bazire, R.; Duhamel, F.

1960-01-01

The authors described the general principles governing the design of a laboratory for experimenting and handling radioactive substances. The difficulties encountered are of two types: 1) those due to the dangers of external irradiation; 2) those due to the dangers of internal contamination. As an example, the authors describe the French achievements in this field and in particular: - the high-activity laboratories at Saclay; - the laboratory for the examination of irradiated fuels at Saclay; - the 'hot' laboratory of the CEN-Grenoble; - the alpha, beta and gamma laboratories of the CEN-Fontenay-aux-Roses. Finally, the report describes the protective materials used for these installations. (author) [fr

Productivity of Veterans Health Administration laboratories: a College of American Pathologists Laboratory Management Index Program (LMIP) study.

Science.gov (United States)

Valenstein, Paul N; Wang, Edward; O'Donohue, Tom

2003-12-01

The Veterans Health Administration (VA) operates the largest integrated laboratory network in the United States. To assess whether the unique characteristics of VA laboratories impact efficiency of operations, we compared the productivity of VA and non-VA facilities. Financial and activity data were prospectively collected from 124 VA and 131 non-VA laboratories enrolled in the College of American Pathologists Laboratory Management Index Program (LMIP) during 2002. In addition, secular trends in 5 productivity ratios were calculated for VA and non-VA laboratories enrolled in LMIP from 1997 through 2002. Veterans Health Administration and non-VA facilities did not differ significantly in size. Inpatients accounted for a lower percentage of testing at VA facilities than non-VA facilities (21.7% vs 37.3%; P benefits; P depreciation, and maintenance than their non-VA counterparts (all P <.001), resulting in lower overall cost per on-site test result (2.64 dollars vs 3.40 dollars; P <.001). Cost per referred (sent-out) test did not differ significantly between the 2 groups. Analysis of 6-year trends showed significant increases in both VA (P <.001) and non-VA (P =.02) labor productivity (on-site tests/total FTE). Expenses at VA laboratories for labor per test, consumables per test, overall expense per test, and overall laboratory expense per discharge decreased significantly during the 6-year period (P <.001), while in non-VA facilities the corresponding ratios showed no significant change. Overall productivity of VA laboratories is superior to that of non-VA facilities enrolled in LMIP. The principal advantages enjoyed by the VA are higher-than-average labor productivity (tests/FTE) and lower-than-average consumable expenses.

Beyond-laboratory-scale prediction for channeling flows through subsurface rock fractures with heterogeneous aperture distributions revealed by laboratory evaluation

Science.gov (United States)

Ishibashi, Takuya; Watanabe, Noriaki; Hirano, Nobuo; Okamoto, Atsushi; Tsuchiya, Noriyoshi

2015-01-01

The present study evaluates aperture distributions and fluid flow characteristics for variously sized laboratory-scale granite fractures under confining stress. As a significant result of the laboratory investigation, the contact area in fracture plane was found to be virtually independent of scale. By combining this characteristic with the self-affine fractal nature of fracture surfaces, a novel method for predicting fracture aperture distributions beyond laboratory scale is developed. Validity of this method is revealed through reproduction of the results of laboratory investigation and the maximum aperture-fracture length relations, which are reported in the literature, for natural fractures. The present study finally predicts conceivable scale dependencies of fluid flows through joints (fractures without shear displacement) and faults (fractures with shear displacement). Both joint and fault aperture distributions are characterized by a scale-independent contact area, a scale-dependent geometric mean, and a scale-independent geometric standard deviation of aperture. The contact areas for joints and faults are approximately 60% and 40%. Changes in the geometric means of joint and fault apertures (µm), em, joint and em, fault, with fracture length (m), l, are approximated by em, joint = 1 × 102 l0.1 and em, fault = 1 × 103 l0.7, whereas the geometric standard deviations of both joint and fault apertures are approximately 3. Fluid flows through both joints and faults are characterized by formations of preferential flow paths (i.e., channeling flows) with scale-independent flow areas of approximately 10%, whereas the joint and fault permeabilities (m2), kjoint and kfault, are scale dependent and are approximated as kjoint = 1 × 10-12 l0.2 and kfault = 1 × 10-8 l1.1.

A Feasibility Study for Mobile Marketing and Distribution Occupational Laboratories in North Dakota.

Science.gov (United States)

Kohns, Donald P.

A study determined the feasibility of a mobile laboratory for marketing and distribution in North Dakota. It attempted to answer four questions: (1) What types of staffing, equipment, curriculum, and delivery systems are presently being utilized in mobile laboratories throughout the nation? (2) What significant information obtained from mobile…

Supplement analysis for continued operation of Lawrence Livermore National Laboratory and Sandia National Laboratories, Livermore. Volume 2: Comment response document

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-03-01

The US Department of Energy (DOE), prepared a draft Supplement Analysis (SA) for Continued Operation of Lawrence Livermore National Laboratory (LLNL) and Sandia National Laboratories, Livermore (SNL-L), in accordance with DOE`s requirements for implementation of the National Environmental Policy Act of 1969 (NEPA) (10 Code of Federal Regulations [CFR] Part 1021.314). It considers whether the Final Environmental Impact Statement and Environmental Impact Report for Continued Operation of Lawrence Livermore National Laboratory and Sandia National Laboratories, Livermore (1992 EIS/EIR) should be supplement3ed, whether a new environmental impact statement (EIS) should be prepared, or no further NEPA documentation is required. The SA examines the current project and program plans and proposals for LLNL and SNL-L, operations to identify new or modified projects or operations or new information for the period from 1998 to 2002 that was not considered in the 1992 EIS/EIR. When such changes, modifications, and information are identified, they are examined to determine whether they could be considered substantial or significant in reference to the 1992 proposed action and the 1993 Record of Decision (ROD). DOE released the draft SA to the public to obtain stakeholder comments and to consider those comments in the preparation of the final SA. DOE distributed copies of the draft SA to those who were known to have an interest in LLNL or SNL-L activities in addition to those who requested a copy. In response to comments received, DOE prepared this Comment Response Document.

[Comparability study of analytical results between a group of clinical laboratories].

Science.gov (United States)

Alsius-Serra, A; Ballbé-Anglada, M; López-Yeste, M L; Buxeda-Figuerola, M; Guillén-Campuzano, E; Juan-Pereira, L; Colomé-Mallolas, C; Caballé-Martín, I

2015-01-01

To describe the study of the comparability of the measurements levels of biological tests processed in biochemistry in Catlab's 4 laboratories. Quality requirements, coefficients of variation and total error (CV% and TE %) were established. Controls were verified with the precision requirements (CV%) in each test and each individual laboratory analyser. Fresh serum samples were used for the comparability study. The differences were analysed using a Microsoft Access® application that produces modified Bland-Altman plots. The comparison of 32 biological parameters that are performed in more than one laboratory and/or analyser generated 306 Bland-Altman graphs. Of these, 101 (33.1%) fell within the accepted range of values based on biological variability, and 205 (66.9%) required revision. Data were re-analysed based on consensus minimum specifications for analytical quality (consensus of the Asociación Española de Farmacéuticos Analistas (AEFA), the Sociedad Española de Bioquímica Clínica y Patología Molecular (SEQC), the Asociación Española de Biopatología Médica (AEBM) and the Sociedad Española de Hematología y Hemoterapia (SEHH), October 2013). With the new specifications, 170 comparisons (56%) fitted the requirements and 136 (44%) required additional review. Taking into account the number of points that exceeded the requirement, random errors, range of results in which discrepancies were detected, and range of clinical decision, it was shown that the 44% that required review were acceptable, and the 32 tests were comparable in all laboratories and analysers. The analysis of the results showed that the consensus requirements of the 4 scientific societies were met. However, each laboratory should aim to meet stricter criteria for total error. Copyright © 2015 SECA. Published by Elsevier Espana. All rights reserved.

A new in-gas-laser ionization and spectroscopy laboratory for off-line studies at KU Leuven

International Nuclear Information System (INIS)

Kudryavtsev, Yu.; Creemers, P.; Ferrer, R.; Granados, C.; Gaffney, L.P.; Huyse, M.; Mogilevskiy, E.; Raeder, S.; Sels, S.; Van den Bergh, P.; Van Duppen, P.; Zadvornaya, A.

2016-01-01

The in-gas laser ionization and spectroscopy (IGLIS) technique is used to produce and to investigate short-lived radioactive isotopes at on-line ion beam facilities. In this technique, the nuclear reaction products recoiling out of a thin target are thermalized and neutralized in a high-pressure noble gas, resonantly ionized by the laser beams in a two-step process, and then extracted from the ion source to be finally accelerated and mass separated. Resonant ionization of radioactive species in the supersonic gas jet ensures very high spectral resolution because of essential reduction of broadening mechanisms. To obtain the maximum efficiency and the best spectral resolution, properties of the supersonic jet and the laser beams must be optimized. To perform these studies a new off-line IGLIS laboratory, including a new high-repetition-rate laser system and a dedicated off-line mass separator, has been commissioned. In this article, the specifications of the different components necessary to achieve optimum conditions in laser-spectroscopy studies of radioactive beams using IGLIS are discussed and the results of simulations are presented.

Hanford 100-N Area Tracer Study Final Report

International Nuclear Information System (INIS)

Kretzschmar, S.P.; Bedi, G.S.; Martinez, P.; Ervin, K.

1996-09-01

This document provides an engineering tracer study final report for the determination of contact time for the disinfection process at Group A Nontransient Noncommunity water treatment plant for the 100- N Water Plant (located on the Hanford Site in Richland, Washington). The purpose of this study is to determine the actual detention time within the plant clearwell, and the disinfection contact time at several clearwell effluent flow rates

Hot laboratory design on the basis of standardized components

International Nuclear Information System (INIS)

Cadrot, J.

1976-01-01

The paper describes the principal effects on hot laboratory design brought about over the last 15 years by the use of standardized components developed jointly with the CEA and the industrial associates of AFINE. After a rapid survey of the various advantages of standardization, the author turns to the specific case of a laboratory producing mixed plutonium and uranium oxide fuels, giving a brief description of the glove-boxes and ancillary equipment. He then deals with the design of an isotope production laboratory. The basic component is the DR 200 standard cell, which permits the civil engineering work to be effected on modular principles. Use of a safety-flow pressure regulating valve makes possible pneumatic automation of the production-cell internals. A substantial gain in output is the result. In the next section the paper refers to a pilot facility for irradiated fuel studies, and describes the components used, which require taking into account the high activities and intense radiations encountered in studies of this type. The author then demonstrates the flexibility with which standardized components can be adapted to different uses, thus solving many distinct problems, an example of which is represented by a semi-hot box for handling up to 100g of americium-241. Finally, the paper offers a rapid summary of the effects of standardization at the various stages concerned, from initial design to the commissioning of a hot laboratory. (author)

The fluid sensor. Narrative of a laboratory study El sensor fluido. La narrativa de una etnografía de laboratorio

Directory of Open Access Journals (Sweden)

César Prestel

2011-03-01

Full Text Available In this article, I present the preliminary outcomes of the field work that I have been developing during the last two years, a laboratory study based on the Actor-Network theory which will be the nucleus of my Ph.D. thesis. Facing the challenge of writing this thesis, I analyze different possible ways of presenting what I have been witnessing in the laboratory. Finally, I propose the possibility of describing the sensor I have been studying as a multiple entity which perhaps might be described using the concept of wrapping. En el presente artículo presento los resultados preliminares del trabajo de campo que he venido realizando durante los últimos dos años y que consiste en una etnografía de laboratorio dirigida a la realización de una tesis doctoral en el marco de la Teoría del Actor-Red. Enfrentado al desafío que supone emprender la redacción de mi trabajo, analizo las diferentes formas de narrar lo que acontece en el laboratorio. Finalmente, concluyo proponiendo la posibilidad de describir el sensor que ha sido objeto de mi estudio como una entidad múltiple que tal vez pueda describirse mediante el concepto de envoltura.

National Renewable Energy Laboratory (NREL) Topic 2 Final Report: End-to-End Communication and Control System to Support Clean Energy Technologies

Energy Technology Data Exchange (ETDEWEB)

Hudgins, Andrew P. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Carrillo, Ismael M. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Jin, Xin [National Renewable Energy Lab. (NREL), Golden, CO (United States); Simmins, John [Electric Power Research Inst. (EPRI), Palo Alto, CA (United States)

2018-02-21

This document is the final report of a two-year development, test, and demonstration project, 'Cohesive Application of Standards- Based Connected Devices to Enable Clean Energy Technologies.' The project was part of the National Renewable Energy Laboratory's (NREL's) Integrated Network Testbed for Energy Grid Research and Technology (INTEGRATE) initiative hosted at Energy Systems Integration Facility (ESIF). This project demonstrated techniques to control distribution grid events using the coordination of traditional distribution grid devices and high-penetration renewable resources and demand response. Using standard communication protocols and semantic standards, the project examined the use cases of high/low distribution voltage, requests for volt-ampere-reactive (VAR) power support, and transactive energy strategies using Volttron. Open source software, written by EPRI to control distributed energy resources (DER) and demand response (DR), was used by an advanced distribution management system (ADMS) to abstract the resources reporting to a collection of capabilities rather than needing to know specific resource types. This architecture allows for scaling both horizontally and vertically. Several new technologies were developed and tested. Messages from the ADMS based on the common information model (CIM) were developed to control the DER and DR management systems. The OpenADR standard was used to help manage grid events by turning loads off and on. Volttron technology was used to simulate a homeowner choosing the price at which to enter the demand response market. Finally, the ADMS used newly developed algorithms to coordinate these resources with a capacitor bank and voltage regulator to respond to grid events.

Final Oak Ridge National Laboratory Site Assessment Report on the Storage of 233U

International Nuclear Information System (INIS)

Bereolos, P.J.; Yong, L.K.

1999-01-01

This assessment characterizes the 233 U inventories and storage facility at Oak Ridge National Laboratory (ORNL). This assessment is a commitment in the U.S. Department of Energy (DOE) Implementation Plan (IP), ''Safe Storage of Uranium-233,'' in response to the Defense Nuclear Facilities Safety Board's Recommendation 97-1

Evaluating dissection in the gross anatomy course: Correlation between quality of laboratory dissection and students outcomes.

Science.gov (United States)

Nwachukwu, Chika; Lachman, Nirusha; Pawlina, Wojciech

2015-01-01

Anatomy learned by active exploration through dissection has many proven benefits including improvement of anatomic knowledge. Decreased laboratory time may affect the quality of dissection and ultimately lower student performance in anatomy translating to lower knowledge acquisition. The aim of this study was to determine whether the quality of students' dissection in teams correlates with their performance in the gross anatomy course. Quality of dissections for each team enrolled in a gross anatomy course at Mayo Medical School was evaluated biweekly using a five-point rubric based on course learning objectives. Assessment of anatomic knowledge was based on sequential laboratory practice practical examination scores, achievements on daily audience response system (ARS) quizzes, and final practical, written, and National Board of Medical Examiners(®) (NBME(®) ) Gross Anatomy and Embryology Subject Examinations. Twelve teams comprising 48 students were included in the study. There was a positive correlation between dissection quality and practice practical examination score (R = 0.83) and a negative correlation between dissection quality and ARS quizzes (R = -0.985). Dissection teams with a passing score on their dissection evaluations (>70%) performed better on their final examinations. Based on an end of course survey, students agreed that dissection evaluations should continue to be a part of the course. This study showed that better quality of dissection was associated with higher scores on practice practical examinations, final practical, written, and NBME examinations. The study demonstrated a positive correlation between dissection evaluations, accompanied by formative feedback during the course, and higher scores on final course assessments. © 2014 American Association of Anatomists.

In situ vitrification application to buried waste: Final report of intermediate field tests at Idaho National Engineering Laboratory

International Nuclear Information System (INIS)

Callow, R.A.; Weidner, J.R.; Loehr, C.A.; Bates, S.O.; Thompson, L.E.; McGrail, B.P.

1991-08-01

This report describes two in situ vitrification field tests conducted on simulated buried waste pits during June and July 1990 at the Idaho National Engineering Laboratory. In situ vitrification, an emerging technology for in place conversion of contaminated soils into a durable glass and crystalline waste form, is being investigated as a potential remediation technology for buried waste. The overall objective of the two tests was to access the general suitability of the process to remediate waste structures representative of buried waste found at Idaho National Engineering Laboratory. In particular, these tests, as part of a treatability study, were designed to provide essential information on the field performance of the process under conditions of significant combustible and metal wastes and to test a newly developed electrode feed technology. The tests were successfully completed, and the electrode feed technology successfully processed the high metal content waste. Test results indicate the process is a feasible technology for application to buried waste. 33 refs., 109 figs., 39 tabs

Iowa Central Quality Fuel Testing Laboratory

Energy Technology Data Exchange (ETDEWEB)

Heach, Don; Bidieman, Julaine

2013-09-30

The objective of this project is to finalize the creation of an independent quality fuel testing laboratory on the campus of Iowa Central Community College in Fort Dodge, Iowa that shall provide the exploding biofuels industry a timely and cost-effective centrally located laboratory to complete all state and federal fuel and related tests that are required. The recipient shall work with various state regulatory agencies, biofuel companies and state and national industry associations to ensure that training and testing needs of their members and American consumers are met. The recipient shall work with the Iowa Department of Ag and Land Stewardship on the development of an Iowa Biofuel Quality Standard along with the Development of a standard that can be used throughout industry.

Selection criteria limit generalizability of smoking pharmacotherapy studies differentially across clinical trials and laboratory studies: A systematic review on varenicline.

Science.gov (United States)

Motschman, Courtney A; Gass, Julie C; Wray, Jennifer M; Germeroth, Lisa J; Schlienz, Nicolas J; Munoz, Diana A; Moore, Faith E; Rhodes, Jessica D; Hawk, Larry W; Tiffany, Stephen T

2016-12-01

The selection criteria used in clinical trials for smoking cessation and in laboratory studies that seek to understand mechanisms responsible for treatment outcomes may limit their generalizability to one another and to the general population. We reviewed studies on varenicline versus placebo and compared eligibility criteria and participant characteristics of clinical trials (N=23) and laboratory studies (N=22) across study type and to nationally representative survey data on adult, daily USA smokers (2014 National Health Interview Survey; 2014 National Survey on Drug Use and Health). Relative to laboratory studies, clinical trials more commonly reported excluding smokers who were unmotivated to quit and for specific medical conditions (e.g., cardiovascular disease, COPD), although both study types frequently reported excluding for general medical or psychiatric reasons. Laboratory versus clinical samples smoked less, had lower nicotine dependence, were younger, and more homogeneous with respect to smoking level and nicotine dependence. Application of common eligibility criteria to national survey data resulted in considerable elimination of the daily-smoking population for both clinical trials (≥47%) and laboratory studies (≥39%). Relative to the target population, studies in this review recruited participants who smoked considerably more and had a later smoking onset age, and were under-representative of Caucasians. Results suggest that selection criteria of varenicline studies limit generalizability in meaningful ways, and differences in criteria across study type may undermine efforts at translational research. Recommendations for improvements in participant selection and reporting standards are discussed. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Needs assessment for fire department services and resources for the Los Alamos National Laboratory, Los Alamos, New Mexico. Final report

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-11-15

This report has been developed in response to a request from the Los Alamos National Laboratory (LANL) to evaluate the need for fire department services so as to enable the Laboratory to plan effective fire protection and thereby: meet LANL`s regulatory and contractual obligations; interface with the Department of Energy (DOE) and other agencies on matters relating to fire and emergency services; and ensure appropriate protection of the community and environment. This study is an outgrowth of the 1993 Fire Department Needs Assessment (prepared for DOE) but is developed from the LANL perspective. Input has been received from cognizant and responsible representatives at LANL, DOE, Los Alamos County (LAC) and the Los Alamos Fire Department (LAFD).

Integrated management system best practices in radioecological laboratories; Sistema de gestao integrado: melhores praticas para laboratorios radioecologicos

Energy Technology Data Exchange (ETDEWEB)

Carvalho, Claudia Aparecida Zerbinatti de

2010-07-01

The research aims to study the best practices to support a conceptual proposal for IMS - Integrated Management System (quality, environment, safety and health) applicable to Radioecology laboratories. The research design is organized into the following steps: in a first step, it was developed the bibliographic and documentary research in IMS, survey and study of standards (QMS ISO 9000 (2005), ISO 9001 (2008), ISO 9004 (2000), EMS ISO 14001 (2004) and OHSMS OHSAS 18001 (2007) and OHSAS 18002 (2008)), identification and characterization of processes in Radioecology Laboratories and study of best practices methodology and benchmarking; in the second stage of the research it was developed a case study (qualitative research, with questionnaires via e-mail and interviews, when possible), preceded by a survey and selection of international and national radioecology laboratories and then these laboratories were contacted and some of them agreed to participate in this research; in the third stage of the research it was built the framework of best practices that showed results that could support the conceptual proposal for the IMS Radioecology Laboratory; the fourth and final stage of research consisted in the construction of the proposed conceptual framework of SGI for Radioecology Laboratory, being then achieved the initial objective of the research. (author)

Laboratory studies of oil spill bioremediation; toward understanding field behavior

International Nuclear Information System (INIS)

Prince, R.C.; Hinton, S.M.; Elmendorf, D.L.; Lute, J.R.; Grossman, M.J.; Robbins, W.K.; Hsu, Chang S.; Richard, B.E.; Haith, C.E.; Senius, J.D.; Minak-Bernero, V.; Chianelli, R.R.; Bragg, J.R.; Douglas, G.S.

1993-01-01

Oil spill remediation aims to enhance the natural process of microbial hydrocarbon biodegradation. The microbial foundations have been studied throughout this century, but the focus of most of this work has been on the degradation of well defined compounds by well defined microbial species. This paper addresses laboratory studies on crude oil biodegradation by microbial consortia obtained from oiled beaches in Prince William Sound, Alaska following the spill from the Exxon Valdez. It demonstrates that oil degradation is indeed likely to be nitrogen-limited in Prince William Sound, the different molecular classes in crude oil that are subjected to biodegradation, the identification of conserved species in the oil that can be used for assessing biodegradation and bioremediation in the field, the effectiveness of fertilizers in stimulating sub-surface biodegradation, the role of the olephilic fertilizer Inipol EAP22, and the identification of the oil-degrading microorganisms in Prince William Sound. Together, these laboratory studies provided guidance and important insights into the microbial phenomena underlying the successful bioremediation of the oiled shorelines

ANALYTICAL MICROBIOLOGY LABORATORY

Data.gov (United States)

Federal Laboratory Consortium — This laboratory contains equipment that performs a broad array of microbiological analyses for pathogenic and spoilage microorganisms. It performs challenge studies...

COGNITIVE PERFORMANCE LABORATORY

Data.gov (United States)

Federal Laboratory Consortium — This laboratory conducts basic and applied human research studies to characterize cognitive performance as influenced by militarily-relevant contextual and physical...

Exploration Laboratory Analysis

Science.gov (United States)

Krihak, M.; Ronzano, K.; Shaw, T.

2016-01-01

The Exploration Laboratory Analysis (ELA) project supports the Exploration Medical Capability (ExMC) risk to minimize or reduce the risk of adverse health outcomes and decrements in performance due to in-flight medical capabilities on human exploration missions. To mitigate this risk, the availability of inflight laboratory analysis instrumentation has been identified as an essential capability for manned exploration missions. Since a single, compact space-ready laboratory analysis capability to perform all exploration clinical measurements is not commercially available, the ELA project objective is to demonstrate the feasibility of emerging operational and analytical capability as a biomedical diagnostics precursor to long duration manned exploration missions. The initial step towards ground and flight demonstrations in fiscal year (FY) 2015 was the down selection of platform technologies for demonstrations in the space environment. The technologies selected included two Small Business Innovation Research (SBIR) performers: DNA Medicine Institutes rHEALTH X and Intelligent Optical Systems later flow assays combined with Holomics smartphone analyzer. The selection of these technologies were based on their compact size, breadth of analytical capability and favorable ability to process fluids in a space environment, among several factors. These two technologies will be advanced to meet ground and flight demonstration success criteria and requirements that will be finalized in FY16. Also, the down selected performers will continue the technology development phase towards meeting prototype deliverables in either late 2016 or 2017.

Development of a Modular Laboratory Information Management System (LIMS) for NAA Laboratories Using Open-Source Developing Tools

International Nuclear Information System (INIS)

Bounakhla, Moussa; Amsil, Hamid; Embarch, K.; Bounouira, Hamid

2018-01-01

CNESTEN designed and developed a modular Laboratory Information Management System (LIMS) for the NAA Laboratory using open-source developing tools. This LIMS ensures a personalized management web space for sample acquisition and preparation, spectra processing and for final analysis of the sample. The system helps also dematerializing process for irradiation requests and for the acquisition of new equipments and samples. It allows managing circulating documents between different actors of the LIMS. Modules for concentration determination, facilities characterization are also included in this LIMS. New modules such as spectra fitting, true coincidence and attenuation corrections can be developed and integrated individually in this system. All data, including nuclear data libraries, are stored in a unique distant database via intranet network to allow instantaneous multi-user access. (author)

Emphasizing interdisciplinarity of control in laboratory courses: illustration with the inverted pendulum

DEFF Research Database (Denmark)

Jouffroy, Jerome; Lottin, Jacques

The importance of control laboratory courses is widely recognized as a crucial part of control education. This paper addresses the role of interdisciplinarity (meaning the different aspects of control) in laboratory courses for undergraduate students. Explanations and ideas are given based....... After running the simulation of the system, qualitative results are described. Finally, some remarks are given to conclude the paper....

Quality of Control of Clinical-Biochemical Laboratories – Serbian Case

Directory of Open Access Journals (Sweden)

Vinko Peric

2014-06-01

Full Text Available In the last 20 years in medical laboratories, numerous activities regarding quality and accreditation system were taken. Approach to this problem in European countries is different, so the task of the Accreditation Work Group of the Confederation of European societies for clinical chemistry (EC 4 to help the efforts to harmonize this issue. External quality control in clinical-chemical laboratories imposed the need for the implementation of quality management system. »Good laboratory practice« and its principles were adopted by nominated bodies, both international and national. In the beginning, the standard ISO 9001 was applied for certification and for accreditation EN 45001 and ISO Guide 25, which are prepared for testing and calibration laboratories. Standard ISO 17025 is the successor of the previous documents and for now it is a reference for mentioned laboratories. Accreditation Work Group of the Confederation of European societies for clinical chemistry (EC 4 made an amendment of the requirements for medical laboratories, which this standard describes. Standard draft ISO 15189 was adopted on February 2003 as a final version with requirements for medical laboratories.

Integrated Data Collection Analysis (IDCA) Program - Final Review September 12, 2012 at DHS

Energy Technology Data Exchange (ETDEWEB)

Sandstrom, Mary M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Brown, Geoffrey W. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Warner, Kirstin F. [Naval Surface Warfare Center (NSWC), Indian Head, MD (United States). Indian Head Division; Phillips, Jason J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Shelley, Timothy J. [Air Force Research Lab. (AFRL), Tyndall AFB, FL (United States); Reyes, Jose A. [Applied Research Associates, Tyndall AFB, FL (United States); Hsu, Peter C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Reynolds, John G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2012-11-26

The Integrated Data Collection Analysis (IDCA) program conducted a final program review at the Department of Homeland Security on September 12, 2012. The review was focused on the results of the program over the complete performance period. A summary presentation delineating the accomplished tasks started the meeting, followed by technical presentations on various issues that arose during the performance period. The presentations were completed with a statistical evaluation of the testing results from all the participants in the IDCA Proficiency Test study. The meeting closed with a discussion of potential sources of funding for continuing work to resolve some of these technical issues. This effort, funded by the Department of Homeland Security (DHS), put the issues of safe handling of these materials in perspective with standard military explosives. The study added Small-Scale Safety and Thermal (SSST) testing results for a broad suite of different HMEs to the literature, and suggested new guidelines and methods to develop safe handling practices for HMEs. Each participating testing laboratory used identical test materials and preparation methods wherever possible. Note, however, the test procedures differ among the laboratories. The results were compared among the laboratories and then compared to historical data from various sources. The testing performers involved were Lawrence Livermore National Laboratory (LLNL), Los Alamos National Laboratory (LANL), Naval Surface Warfare Center, Indian Head Division (NSWC IHD), Sandia National Laboratories (SNL), and Air Force Research Laboratory, Tyndall AFB (AFRL/RXQL). These tests were conducted as a proficiency study in order to establish some consistency in test protocols, procedures, and experiments and to compare results when these testing variables cannot be made consistent.

An ECVAG inter-laboratory validation study of the comet assay

DEFF Research Database (Denmark)

Ersson, Clara; Møller, Peter; Forchhammer, Lykke

2013-01-01

of ionising radiation, inter-laboratory variation, intra-laboratory variation and residual variation contributed to 60.9, 19.4, 0.1 and 19.5%, respectively, of the total variation. In the coded PBMC samples, the inter-laboratory variation explained the largest fraction of the overall variation of DNA strand...

The impact of laboratory quality assurance standards on laboratory operational performance

Directory of Open Access Journals (Sweden)

E Ratseou

2014-01-01

Full Text Available It has become a trend for companies to implement and be certified to various quality management systems so as to improve consistency, reliability, and quality of product delivery to customers. The most common quality management systems adopted are the ISO 9000 series of standards for manufacturing and services related organisations, with ISO 17025 and Good Laboratory Practices (GLP standards adopted specifically by laboratories as quality assurance initiatives. There are various reports on the impact of the ISO 9000 series on organisational performance but no studies or reports have been done on the performance of laboratory standards. Therefore this article reports on a study conducted to investigate the impact of ISO 17025 and GLP on the operational performance of both commercial and non-commercial laboratories. A qualitative research study was conducted to examine the impact standards on the aspects of health and safety, supplier selection and performance, human resources, customer satisfaction and profitability of the laboratory. The data collected suggest that there is no difference in laboratory operational performance with or without the standards. In other words it appears that the basic fundamental requirements inherent with laboratories are sufficient to perform both operationally and optimally. This leads to the view that standards are implemented as a customer requirement and not as an operational requirement.

Site-selection studies for final disposal of spent fuel in Finland

International Nuclear Information System (INIS)

Vuorela, P.; Aeikaes, T.

1984-02-01

In the management of waste by the Industrial Power Company Ltd. (TVO) preparations are being made for the final disposal of unprocessed spent fuel into the Finnish bedrock. The site selection program will advance in three phases. The final disposal site must be made at the latest by the end of the year 2000, in accordance with a decision laid down by the Finnish Government. In the first phase, 1983-85, the main object is to find homogeneous stable bedrock blocks surrounded by fracture zones located at a safe distance from the planned disposal area. The work usually starts with a regional structural analysis of mosaics of Landsat-1 winter and summer imagery. Next an assortment of different maps, which cover the whole country, is used. Technical methods for geological and hydrogeological site investigations are being developed during the very first phase of the studies, and a borehole 1000 meters deep will be made in southwestern Finland. Studies for the final disposal of spent fuel or high-level reprocessing waste have been made since 1974 in Finland. General suitability studies of the bedrock have been going on since 1977. The present results indicate that suitable investigation areas for the final disposal of highly active waste can be found in Finland

Medicare program; payment policies under the physician fee schedule, five-year review of work relative value units, clinical laboratory fee schedule: signature on requisition, and other revisions to part B for CY 2012. Final rule with comment period.

Science.gov (United States)

2011-11-28

This final rule with comment period addresses changes to the physician fee schedule and other Medicare Part B payment policies to ensure that our payment systems are updated to reflect changes in medical practice and the relative value of services. It also addresses, implements or discusses certain statutory provisions including provisions of the Patient Protection and Affordable Care Act, as amended by the Health Care and Education Reconciliation Act of 2010 (collectively known as the Affordable Care Act) and the Medicare Improvements for Patients and Providers Act (MIPPA) of 2008. In addition, this final rule with comment period discusses payments for Part B drugs; Clinical Laboratory Fee Schedule: Signature on Requisition; Physician Quality Reporting System; the Electronic Prescribing (eRx) Incentive Program; the Physician Resource-Use Feedback Program and the value modifier; productivity adjustment for ambulatory surgical center payment system and the ambulance, clinical laboratory, and durable medical equipment prosthetics orthotics and supplies (DMEPOS) fee schedules; and other Part B related issues.

Veterinary Laboratory Services Study - 1976.

Science.gov (United States)

1976-09-01

years. Many tests , such as ;uman pregnancy testing , Mycobacterium tuberculosis isolation and :iers have been converted to in—vitro procedures. Sheep...assignment in laboratories and worked in chemistry , mic robiology , or diagnostic areas can be directly uti l ized with little additional orientation. They...Chorionic Gonadotropin 475 730 17 1,222 UCG or Human Pregnancy 147 42 189 Tularemia 332 332 OX—19 211 211 Salmonella 219 219 Trichinella 17 17 Venipuncture

Thermogravimetric Analysis Laboratory

Data.gov (United States)

Federal Laboratory Consortium — At NETL’s Thermogravimetric Analysis Laboratory in Morgantown, WV, researchers study how chemical looping combustion (CLC) can be applied to fossil energy systems....

USAF Summer Research Program - 1995 High School Apprenticeship Program Final Reports, Volume 14, Rome Laboratory

National Research Council Canada - National Science Library

Moore, Gary

1995-01-01

The United States Air Force High School Apprenticeship Program's (USAF HSAP) purpose is to place outstanding high school students whose interests are in the areas of mathematics, engineering, and science to work in a laboratory environment...

Exploring the Potential of Smartphones and Tablets for Performance Support in Food Chemistry Laboratory Classes

Science.gov (United States)

van der Kolk, Koos; Hartog, Rob; Beldman, Gerrit; Gruppen, Harry

2013-12-01

Increasingly, mobile applications appear on the market that can support students in chemistry laboratory classes. In a multiple app-supported laboratory, each of these applications covers one use-case. In practice, this leads to situations in which information is scattered over different screens and written materials. Such a multiple app-supported laboratory will become awkward with the growth of the number of applications and use cases. In particular, using and switching between applications is likely to induce extraneous cognitive load that can easily be avoided. The manuscript describes the design of a prototype smartphone web app (LabBuddy) designed to support students in food chemistry laboratory classes. The manuscript describes a case study ( n = 26) of the use of a LabBuddy prototype in such a laboratory class. Based on the evaluation of this case study, design requirements for LabBuddy were articulated. LabBuddy should work on HTML5 capable devices, independent of screen size, by having a responsive layout. In addition, LabBuddy should enable a student using LabBuddy to switch between devices without much effort. Finally, LabBuddy should offer an integrated representation of information.

Hydraulic manipulator design, analysis, and control at Oak Ridge National Laboratory

Energy Technology Data Exchange (ETDEWEB)

Kress, R.L.; Jansen, J.F. [Oak Ridge National Lab., TN (United States). Robotics and Process Systems Div.; Love, L.J. [Oak Ridge Inst. for Science and Education, TN (United States); Basher, A.M.H. [South Carolina State Univ., Orangeburg, SC (United States)

1996-09-01

To meet the increased payload capacities demanded by present-day tasks, manipulator designers have turned to hydraulics as a means of actuation. Hydraulics have always been the actuator of choice when designing heavy-life construction and mining equipment such as bulldozers, backhoes, and tunneling devices. In order to successfully design, build, and deploy a new hydraulic manipulator (or subsystem) sophisticated modeling, analysis, and control experiments are usually needed. To support the development and deployment of new hydraulic manipulators Oak Ridge National Laboratory (ORNL) has outfitted a significant experimental laboratory and has developed the software capability for research into hydraulic manipulators, hydraulic actuators, hydraulic systems, modeling of hydraulic systems, and hydraulic controls. The hydraulics laboratory at ORNL has three different manipulators. First is a 6-Degree-of-Freedom (6-DoF), multi-planer, teleoperated, flexible controls test bed used for the development of waste tank clean-up manipulator controls, thermal studies, system characterization, and manipulator tracking. Finally, is a human amplifier test bed used for the development of an entire new class of teleoperated systems. To compliment the hardware in the hydraulics laboratory, ORNL has developed a hydraulics simulation capability including a custom package to model the hydraulic systems and manipulators for performance studies and control development. This paper outlines the history of hydraulic manipulator developments at ORNL, describes the hydraulics laboratory, discusses the use of the equipment within the laboratory, and presents some of the initial results from experiments and modeling associated with these hydraulic manipulators. Included are some of the results from the development of the human amplifier/de-amplifier concepts, the characterization of the thermal sensitivity of hydraulic systems, and end-point tracking accuracy studies. Experimental and analytical

Hydraulic manipulator design, analysis, and control at Oak Ridge National Laboratory

International Nuclear Information System (INIS)

Kress, R.L.; Jansen, J.F.; Basher, A.M.H.

1996-09-01

To meet the increased payload capacities demanded by present-day tasks, manipulator designers have turned to hydraulics as a means of actuation. Hydraulics have always been the actuator of choice when designing heavy-life construction and mining equipment such as bulldozers, backhoes, and tunneling devices. In order to successfully design, build, and deploy a new hydraulic manipulator (or subsystem) sophisticated modeling, analysis, and control experiments are usually needed. To support the development and deployment of new hydraulic manipulators Oak Ridge National Laboratory (ORNL) has outfitted a significant experimental laboratory and has developed the software capability for research into hydraulic manipulators, hydraulic actuators, hydraulic systems, modeling of hydraulic systems, and hydraulic controls. The hydraulics laboratory at ORNL has three different manipulators. First is a 6-Degree-of-Freedom (6-DoF), multi-planer, teleoperated, flexible controls test bed used for the development of waste tank clean-up manipulator controls, thermal studies, system characterization, and manipulator tracking. Finally, is a human amplifier test bed used for the development of an entire new class of teleoperated systems. To compliment the hardware in the hydraulics laboratory, ORNL has developed a hydraulics simulation capability including a custom package to model the hydraulic systems and manipulators for performance studies and control development. This paper outlines the history of hydraulic manipulator developments at ORNL, describes the hydraulics laboratory, discusses the use of the equipment within the laboratory, and presents some of the initial results from experiments and modeling associated with these hydraulic manipulators. Included are some of the results from the development of the human amplifier/de-amplifier concepts, the characterization of the thermal sensitivity of hydraulic systems, and end-point tracking accuracy studies. Experimental and analytical

Neural Systems Laboratory

Data.gov (United States)

Federal Laboratory Consortium — As part of the Electrical and Computer Engineering Department and The Institute for System Research, the Neural Systems Laboratory studies the functionality of the...

On the role of final-state interactions in Dalitz plot studies

International Nuclear Information System (INIS)

Kubis, Bastian; Niecknig, Franz; Schneider, Sebastian P.

2012-01-01

The study of Dalitz plots of heavy-meson decays to multi-hadron final states has received intensified interest by the possibility to gain access to precision investigations of CP violation. A thorough understanding of the hadronic final-state interactions is a prerequisite to achieve a highly sensitive, model-independent study of such Dalitz plots. We illustrate some of the theoretical tools, predominantly taken from dispersion theory, available for these and related purposes, and discuss the low-energy decays ω,φ→3π in some more detail.

On the role of final-state interactions in Dalitz plot studies

Energy Technology Data Exchange (ETDEWEB)

Kubis, Bastian, E-mail: kubis@hiskp.uni-bonn.de [Helmholtz-Institut fuer Strahlen- und Kernphysik and Bethe Center for Theoretical Physics, Universitaet Bonn (Germany); Niecknig, Franz; Schneider, Sebastian P. [Helmholtz-Institut fuer Strahlen- und Kernphysik and Bethe Center for Theoretical Physics, Universitaet Bonn (Germany)

2012-04-15

The study of Dalitz plots of heavy-meson decays to multi-hadron final states has received intensified interest by the possibility to gain access to precision investigations of CP violation. A thorough understanding of the hadronic final-state interactions is a prerequisite to achieve a highly sensitive, model-independent study of such Dalitz plots. We illustrate some of the theoretical tools, predominantly taken from dispersion theory, available for these and related purposes, and discuss the low-energy decays {omega},{phi}{yields}3{pi} in some more detail.

On the role of final-state interactions in Dalitz plot studies

Science.gov (United States)

Kubis, Bastian; Niecknig, Franz; Schneider, Sebastian P.

2012-04-01

The study of Dalitz plots of heavy-meson decays to multi-hadron final states has received intensified interest by the possibility to gain access to precision investigations of CP violation. A thorough understanding of the hadronic final-state interactions is a prerequisite to achieve a highly sensitive, model-independent study of such Dalitz plots. We illustrate some of the theoretical tools, predominantly taken from dispersion theory, available for these and related purposes, and discuss the low-energy decays ω,ϕ→3π in some more detail.

Safety in laboratories: Indian scenario.

Science.gov (United States)

Mustafa, Ajaz; Farooq, A Jan; Qadri, Gj; S A, Tabish

2008-07-01

Health and safety in clinical laboratories is becoming an increasingly important subject as a result of emergence of highly infectious diseases such as Hepatitis and HIV. A cross sectional study was carried out to study the safety measures being adopted in clinical laboratories of India. Heads of laboratories of teaching hospitals of India were subjected to a standardized, pretested questionnaire. Response rate was 44.8%. only 60% of laboratories had person in-charge of safety in laboratory. Seventy three percent of laboratories had safety education program regarding hazards. In 91% of laboratories staff is using protective clothing while working in laboratories. Hazardous material regulations are followed in 78% of laboratories. Regular health check ups are carried among laboratory staff in 43.4% of laboratories.Safety manual is available in 56.5% of laboratories. 73.9% of laboratories are equipped with fire extinguishers. Fume cupboards are provided in 34.7% of laboratories and they are regularly checked in 87.5% of these laboratories. In 78.26% of laboratories suitable measures are taken to minimize formation of aerosols.In 95.6% of laboratories waste is disposed off as per bio-medical waste management handling rules. Laboratory of one private medical college was accredited with NABL and safety parameters were better in that laboratory. Installing safety engineered devices apparently contributes to significant decrease in injuries in laboratories; laboratory safety has to be a part of overall quality assurance programme in hospitals. Accreditation has to be made necessary for all laboratories.

Seismic hazard studies for the high flux beam reactor at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Costantino, C.J.; Heymsfield, E.; Park, Y.J.; Hofmayer, C.H.

1991-01-01

This paper presents the results of a calculation to determine the site specific seismic hazard appropriate for the deep soil site at Brookhaven National Laboratory (BNL) which is to be used in the risk assessment studies being conducted for the High Flux Beam Reactor (HFBR). The calculations use as input the seismic hazard defined for the bedrock outcrop by a study conducted at Lawrence Livermore National Laboratory (LLNL). Variability in site soil properties were included in the calculations to obtain the seismic hazard at the ground surface and compare these results with those using the generic amplification factors from the LLNL study

Argonne National Laboratory institutional plan FY 2001--FY 2006.

Energy Technology Data Exchange (ETDEWEB)

Beggs, S.D.

2000-12-07

This Institutional Plan describes what Argonne management regards as the optimal future development of Laboratory activities. The document outlines the development of both research programs and support operations in the context of the nation's R and D priorities, the missions of the Department of Energy (DOE) and Argonne, and expected resource constraints. The Draft Institutional Plan is the product of many discussions between DOE and Argonne program managers, and it also reflects programmatic priorities developed during Argonne's summer strategic planning process. That process serves additionally to identify new areas of strategic value to DOE and Argonne, to which Laboratory Directed Research and Development funds may be applied. The Draft Plan is provided to the Department before Argonne's On-Site Review. Issuance of the final Institutional Plan in the fall, after further comment and discussion, marks the culmination of the Laboratory's annual planning cycle. Chapter II of this Institutional Plan describes Argonne's missions and roles within the DOE laboratory system, its underlying core competencies in science and technology, and six broad planning objectives whose achievement is considered critical to the future of the Laboratory. Chapter III presents the Laboratory's ''Science and Technology Strategic Plan,'' which summarizes key features of the external environment, presents Argonne's vision, and describes how Argonne's strategic goals and objectives support DOE's four business lines. The balance of Chapter III comprises strategic plans for 23 areas of science and technology at Argonne, grouped according to the four DOE business lines. The Laboratory's 14 major initiatives, presented in Chapter IV, propose important advances in key areas of fundamental science and technology development. The ''Operations and Infrastructure Strategic Plan'' in Chapter V includes

A statistical analysis of student questions in a cell biology laboratory.

Science.gov (United States)

Keeling, Elena L; Polacek, Kelly M; Ingram, Ella L

2009-01-01

Asking questions is an essential component of the practice of science, but question-asking skills are often underemphasized in science education. In this study, we examined questions written by students as they prepared for laboratory exercises in a senior-level cell biology class. Our goals were to discover 1) what types of questions students asked about laboratory activities, 2) whether the types or quality of questions changed over time, and 3) whether the quality of questions or degree of improvement was related to academic performance. We found a majority of questions were about laboratory outcomes or seeking additional descriptive information about organisms or processes to be studied. Few questions earned the highest possible ranking, which required demonstration of extended thought, integration of information, and/or hypotheses and future experiments, although a majority of students asked such a question at least once. We found no correlation between types of student questions or improvement in questions and final grades. Only a small improvement in overall question quality was seen despite considerable practice at writing questions about science. Our results suggest that improving students' ability to generate higher-order questions may require specific pedagogical intervention.

PIGMI program at the Los Alamos Scientific Laboratory

International Nuclear Information System (INIS)

Stovall, J.E.

1980-09-01

The PIGMI Program has completed 3-1/2 yr of a project to develop the technology for the optimal pion generator for medical irradiations (PIGMI). The major accomplishments under the program include completion of the injector beam measurements; completion of the 440-MHz radio-frequency (rf) power source; assembly and test of the alternating phase focusing accelerator section; development of the rf-quadrupole (RFQ) beam-dynamics program, PARMTEQ; design, fabrication, assembly, and test of the RFQ accelerator; final decision on low-energy configuration for PIGMI; assembly of the drift-tube linac section of the PIGMI Prototype; completion of sample set of permanent magnet quadrupoles; optimization of the disk-and-washer (DAW) cavity geometry; fabrication of model cavities of the DAW; final decision on DAW support geometry; acquisition of additional laboratory space for the DAW power test; partial assembly of the 1320-MHz rf power source for the DAW test; and pion channel design studies

Mirror Advanced Reactor Study (MARS) final report summary

International Nuclear Information System (INIS)

Henning, C.D.; Logan, B.G.; Carlson, G.A.

1983-01-01

The Mirror Advanced Reactor Study (MARS) has resulted in an overview of a first-generation tandem mirror reactor. The central cell fusion plasma is self-sustained by alpha heating (ignition), while electron-cyclotron resonance heating and negative ion beams maintain the electrostatic confining potentials in the end plugs. Plug injection power is reduced by the use of high-field choke coils and thermal barriers, concepts to be tested in the Tandem Mirror Experiment-Upgrade (TMX-U) and Mirror Fusion Test Facility (MFTF-B) at Lawrence Livermore National Laboratory

Plant systems/components modularization study. Final report. [PWR

Energy Technology Data Exchange (ETDEWEB)

1977-07-01

The final results are summarized of a Plant Systems/Components Modularization Study based on Stone and Webster's Pressurized Water Reactor Reference Design. The program has been modified to include evaluation of the most promising areas for modular consideration based on the level of the Sundesert Project engineering design completion and the feasibility of their incorporation into the plant construction effort.

High Performance Fuel Laboratory, Hanford Reservation, Richland, Washington. Final environmental impact statement

International Nuclear Information System (INIS)

1977-09-01

The High Performance Fuel Laboratory (HPFL) will provide pilot scale tests of manufacturing processes, equipment, and handling systems and of accountability and safeguards, methods, and equipment while keeping radiological and chemical exposures of the workers, public, and environment at the lowest practicable levels. The experience gained from designing, constructing and operating the HPFL can be used in future commitments to commercial fuel fabrication plants in the late 1980s and beyond for processing of nuclear fuel. The HPFL site is located in the 400 Area of the 559-square mile, federally owned Hanford Reservation. This environmental impact statement considers effects of the HPFL under normal conditions and in the event of an accident

PHENOMENOLOGICAL APPROACHES TO STUDY LEARNING IN THE TERTIARY LEVEL CHEMISTRY LABORATORY

Directory of Open Access Journals (Sweden)

Santiago Sandi-Urena

Full Text Available Despite the widespread notion amongst chemistry educators that the laboratory is essential to learn chemistry, it is often a neglected area of teaching and, arguably, of educational research. Research has typically focused on secondary education, single institutions, and isolated interventions that are mostly assessed quantitatively. It has also honed in on compartmentalised features instead of searching understanding of broader aspects of learning through experimentation. This paper contends there is a gap in subject specific, tertiary level research that is comprehensive and learning-centred instead of fragmented and instruction-based. A shift in focus requires consideration of methodological approaches that can effectively tackle the challenges of researching complex learning environments. This paper reckons qualitative approaches, specifically phenomenology, are better suited for this purpose. To illustrate this potential, it summarises an exemplar phenomenological study that investigated students’ experience of change in instructional style from an expository (traditional laboratory program to one that was cooperative and project-based (reformed. The study suggests the experience was characterised by a transition from a learning environment that promoted mindless behaviour to one in which students were mindfully engaged in their learning. Thus, this work puts forth the use of Mindfulness Theory to investigate and support design of laboratory experiences.

Road Transportable Analytical Laboratory (RTAL) system

International Nuclear Information System (INIS)

Finger, S.M.

1995-01-01

U.S. Department of Energy (DOE) facilities around the country have, over the years, become contaminated with radionuclides and a range of organic and inorganic wastes. Many of the DOE sites encompass large land areas and were originally sited in relatively unpopulated regions of the country to minimize risk to surrounding populations. In addition, wastes were sometimes stored underground at the sites in 55-gallon drums, wood boxes or other containers until final disposal methods could be determined. Over the years, these containers have deteriorated, releasing contaminants into the surrounding environment. This contamination has spread, in some cases polluting extensive areas. The DOE would benefit greatly if it had reliable, road transportable, fully independent laboratory systems that could perform on-site the full range of analyses required. The goal of the Road Transportable Analytical Laboratory (RTAL) project is the development and demonstration of a system to meet the unique needs of the DOE for rapid, accurate analysis of a wide variety of hazardous and radioactive contaminants in soils, ground water and surface waters. This document describes the requirements for such a laboratory

A semester-long project-oriented biochemistry laboratory based on Helicobacter pylori urease.

Science.gov (United States)

Farnham, Kate R; Dube, Danielle H

2015-01-01

Here we present the development of a 13 week project-oriented biochemistry laboratory designed to introduce students to foundational biochemical techniques and then enable students to perform original research projects once they have mastered these techniques. In particular, we describe a semester-long laboratory that focuses on a biomedically relevant enzyme--Helicobacter pylori (Hp) urease--the activity of which is absolutely required for the gastric pathogen Hp to colonize the human stomach. Over the course of the semester, students undertake a biochemical purification of Hp urease, assess the success of their purification, and investigate the activity of their purified enzyme. In the final weeks of the semester, students design and implement their own experiments to study Hp urease. This laboratory provides students with an understanding of the importance of biochemistry in human health while empowering them to engage in an active area of research. © 2015 The International Union of Biochemistry and Molecular Biology.

Nanomaterial Case Study: Nanoscale Silver in Disinfectant Spray (Final Report)

Science.gov (United States)

EPA announced the release of the final report, Nanomaterial Case Study: Nanoscale Silver in Disinfectant Spray. This report represents a case study of engineered nanoscale silver (nano-Ag), focusing on the specific example of nano-Ag as possibly used in disinfectant spr...

Studies of nuclear processes at the Triangle Universities Nuclear Laboratory. Final report

International Nuclear Information System (INIS)

2000-01-01

The authors concluded their program to establish the trends of isospin mixing in nuclei ranging from 12 C to 40 Ca. This program revealed a systematic variation in the proton reduced widths from one A = 4N nucleus to the next as T = 0 nuclei were bombarded by protons and T = 3/2 states were populated in the compound system. In few-body physics, their program of studies of D-state properties of light nuclei ( 3 H, 3 He, and 4 He) resulted in precise determinations of the η parameters for 3 He and 3 H which agreed well with theoretical predictions and served as an important constraint on theoretical calculations. The D 2 parameter determination for 4 He, carried out in collaboration with researchers at Munich and Lisbon, was not as precise but did indicate that 4 He has significant deformation. A program was initiated during this period to measure the ratio of asymptotic D- to S-state normalization constant (η) for 6 Li at Florida State University using the ( 6 Li,d) reaction. They determined that the η parameter for 6 Li is extremely small, contrary to expectations

[The external evaluation of study quality: the role in maintaining the reliability of laboratory information].

Science.gov (United States)

Men'shikov, V V

2013-08-01

The external evaluation of quality of clinical laboratory examinations was gradually introduced in USSR medical laboratories since 1970s. In Russia, in the middle of 1990 a unified all-national system of external evaluation quality was organized known as the Federal center of external evaluation of quality at the basis of laboratory of the state research center of preventive medicine. The main positions of policy in this area were neatly formulated in the guidance documents of ministry of Health. Nowadays, the center of external evaluation of quality proposes 100 and more types of control studies and permanently extends their specter starting from interests of different disciplines of clinical medicine. The consistent participation of laboratories in the cycles of external evaluation of quality intrinsically promotes improvement of indicators of properness and precision of analysis results and increases reliability of laboratory information. However, a significant percentage of laboratories does not participate at all in external evaluation of quality or takes part in control process irregularly and in limited number of tests. The managers of a number of medical organizations disregard the application of the proposed possibilities to increase reliability of laboratory information and limit financing of studies in the field of quality control. The article proposes to adopt the national standard on the basis of ISO 17043 "Evaluation of compliance. The common requirements of professional competence testing".

Comparative study of bedside and laboratory measurements of hemoglobin.

Science.gov (United States)

Krenzischek, D A; Tanseco, F V

1996-11-01

The purpose of this study was to examine the effects of variations in technique on measurements of hemoglobin level done at the bedside and to compare these results with laboratory measurements of hemoglobin. In accordance with hospital policy, procedure, and protocol, various techniques were used to obtain samples of capillary and venous blood and of blood from arterial and central venous catheters. Levels of hemoglobin were measured at the bedside and in the laboratory, and the results were compared. The Johns Hopkins Hospital adult postanesthesia care unit. A total of 187 blood samples were obtained from 62 adults who had undergone general surgery. Group I comprised 20 subjects with capillary and venous blood samples. Group II comprised 21 subjects with arterial blood samples. Group III comprised 21 subjects with central venous blood samples. The results showed that the amount of blood to be discarded before obtaining samples of arterial and central venous blood need not be any larger than double the dead space of the catheter, and that shaking the blood sample for 10 seconds was sufficient to mix the sample before measurement of hemoglobin levels. Results of bedside and laboratory measurements of hemoglobin level were comparable. Bedside measurement of hemoglobin increases efficiency in patient care, decreases risk of blood-transmitted infection for staff, and decreases cost to the patient. However, the persons who perform the assay must be responsible in adhering to the standard of practice to minimize errors in the measurements.

Aespoe hard rock laboratory. Annual report 2010

Energy Technology Data Exchange (ETDEWEB)

2011-02-15

The Aespoe Hard Rock Laboratory (HRL) is an important part of SKB's work with the design and construction of a deep geological repository for the final disposal of spent nuclear fuel. Aespoe HRL is located in the Simpevarp area in the municipality of Oskarshamn. One of the fundamental reasons behind SKB's decision to construct an underground laboratory was to create opportunities for research, development and demonstration in a realistic and undisturbed rock environment down to repository depth. The underground part of the laboratory consists of a tunnel from the Simpevarp peninsula to the southern part of Aespoe where the tunnel continues in a spiral down to a depth of 460 m. Aespoe HRL has been in operation since 1995 and considerable international interest has been shown in its research, as well as in the development and demonstration tasks. A summary of the work performed at Aespoe HRL during 2010 is given below

Aespoe Hard Rock Laboratory. Annual Report 2011

Energy Technology Data Exchange (ETDEWEB)

NONE

2012-03-15

The Aespoe Hard Rock Laboratory (HRL) is an important part of SKB's work with the design and construction of a deep geological repository for the final disposal of spent nuclear fuel. Aespoe HRL is located in the Simpevarp area in the municipality of Oskarshamn. One of the fundamental reasons behind SKB's decision to construct an underground laboratory was to create opportunities for research, development and demonstration in a realistic and undisturbed rock environment down to repository depth. The underground part of the laboratory consists of a tunnel from the Simpevarp peninsula to the southern part of Aespoe where the tunnel continues in a spiral down to a depth of 460 m. Aespoe HRL has been in operation since 1995 and considerable international interest has been shown in its research, as well as in the development and demonstration tasks. A summary of the work performed at Aespoe HRL during 2011 is given below.

Aespoe hard rock laboratory. Annual report 2010

International Nuclear Information System (INIS)

2011-02-01

The Aespoe Hard Rock Laboratory (HRL) is an important part of SKB's work with the design and construction of a deep geological repository for the final disposal of spent nuclear fuel. Aespoe HRL is located in the Simpevarp area in the municipality of Oskarshamn. One of the fundamental reasons behind SKB's decision to construct an underground laboratory was to create opportunities for research, development and demonstration in a realistic and undisturbed rock environment down to repository depth. The underground part of the laboratory consists of a tunnel from the Simpevarp peninsula to the southern part of Aespoe where the tunnel continues in a spiral down to a depth of 460 m. Aespoe HRL has been in operation since 1995 and considerable international interest has been shown in its research, as well as in the development and demonstration tasks. A summary of the work performed at Aespoe HRL during 2010 is given below

Aespoe Hard Rock Laboratory. Annual Report 2011

International Nuclear Information System (INIS)

2012-03-01

The Aespoe Hard Rock Laboratory (HRL) is an important part of SKB's work with the design and construction of a deep geological repository for the final disposal of spent nuclear fuel. Aespoe HRL is located in the Simpevarp area in the municipality of Oskarshamn. One of the fundamental reasons behind SKB's decision to construct an underground laboratory was to create opportunities for research, development and demonstration in a realistic and undisturbed rock environment down to repository depth. The underground part of the laboratory consists of a tunnel from the Simpevarp peninsula to the southern part of Aespoe where the tunnel continues in a spiral down to a depth of 460 m. Aespoe HRL has been in operation since 1995 and considerable international interest has been shown in its research, as well as in the development and demonstration tasks. A summary of the work performed at Aespoe HRL during 2011 is given below

Aespoe hard rock laboratory. Annual report 2010

Energy Technology Data Exchange (ETDEWEB)

2011-02-15

The Aespoe Hard Rock Laboratory (HRL) is an important part of SKB's work with the design and construction of a deep geological repository for the final disposal of spent nuclear fuel. Aespoe HRL is located in the Simpevarp area in the municipality of Oskarshamn. One of the fundamental reasons behind SKB's decision to construct an underground laboratory was to create opportunities for research, development and demonstration in a realistic and undisturbed rock environment down to repository depth. The underground part of the laboratory consists of a tunnel from the Simpevarp peninsula to the southern part of Aespoe where the tunnel continues in a spiral down to a depth of 460 m. Aespoe HRL has been in operation since 1995 and considerable international interest has been shown in its research, as well as in the development and demonstration tasks. A summary of the work performed at Aespoe HRL during 2010 is given below

Case study: improving efficiency in a large hospital laboratory.

Science.gov (United States)

Bartel, Marilynn

2004-01-01

Saint Francis Health System (SFHS) consists of three hospitals and one clinic: Saint Francis Hospital (SFH); Broken Arrow Medical Center; Laureate Psychiatric Hospital; and Warren Clinic. SFHS has 670 physicians on staff and serves medical (oncology, orthopedic, neurology, and renal), surgical, cardiac, women and infant, pediatric, transplant, and trauma patients in Tulsa County, Oklahoma, which has a population of 660,000. SFH incorporates 706 staffed beds, including 126 pediatric beds and 119 critical care beds. Each year, the health system averages 38,000 admissions, 70,000 emergency department visits, 25,000 surgeries, and 3,500 births. Saint Francis Laboratory is located within the main hospital facility (SFH) and functions as a core lab for the health system. The lab also coordinates lab services with Saint Francis Heart Hospital, a physician-system joint venture. The Optimal Equipment Configuration (OEC) Project was designed by the Clinical Laboratory Services division of Premier, a group purchasing organization, with the goal of determining whether laboratories could improve efficiency and decrease unit cost by using a single-source vendor. Participants included seven business partners (Abbott, Bayer, Beckman/Coulter, Dade/Behring, J&J/ Ortho, Olympus, and Roche) and 21 laboratory sites (a small, mid-sized, and large site for each vendor). SFH laboratory staff embraced Premier's concept and viewed the OEC project as an opportunity to "energize" laboratory operations. SFH partnered with Abbott, their primary equipment vendor, for the project. Using resources and tools made available through the project, the laboratory was re-engineered to simplify workflow, increase productivity, and decrease costs by adding automation and changing to centralized specimen processing. Abbott and SFH shared a common vision for the project and enhanced their partnership through increased communication and problem solving. Abbott's area representatives provided for third

Advancing internal erosion monitoring using seismic methods in field and laboratory studies

Science.gov (United States)

Parekh, Minal L.

embankment surface. Analysis of root mean squared amplitude and AE threshold counts indicated activity focused at the toe in locations matching the sand boils. This analysis also compared the various detection methods employed at the 2012 test to discuss a timeline of detection related to observable behaviors of the structure. The second area of research included designing and fabricating an instrumented laboratory apparatus for investigating active seismic wave propagation through soil samples. This dissertation includes a description of the rigid wall permeameter, instrumentation, control, and acquisitions systems along with descriptions of the custom-fabricated seismic sensors. A series of experiments (saturated sand, saturated sand with a known static anomaly placed near the center of the sample, and saturated sand with a diminishing anomaly near the center of the sample) indicated that shear wave velocity changes reflected changes in the state of stress of the soil. The mean effective stress was influenced by the applied vertical axial load, the frictional interaction between the soil and permeameter wall, and the degree of preloading. The frictional resistance was sizeable at the sidewall of the permeameter and decreased the mean effective stress with depth. This study also included flow tests to monitor changes in shear wave velocities as the internal erosion process started and developed. Shear wave velocity decreased at voids or lower density zones in the sample and increased as arching redistributes loads, though the two conditions compete. Finally, the social and political contexts surrounding nondestructive inspection were considered. An analogous approach utilized by the aerospace industry was introduced: a case study comparing the path toward adopting nondestructive tools as standard practices in monitoring aircraft safety. Additional lessons for dam and levee safety management were discussed from a Science, Technology, Engineering, and Policy (STEP

Field Research Studying Whales in an Undergraduate Animal Behavior Laboratory

Science.gov (United States)

MacLaren, R. David; Schulte, Dianna; Kennedy, Jen

2012-01-01

This work describes a new field research laboratory in an undergraduate animal behavior course involving the study of whale behavior, ecology and conservation in partnership with a non-profit research organization--the Blue Ocean Society for Marine Conservation (BOS). The project involves two weeks of training and five weekend trips on whale watch…

Laboratory quality management system: Road to accreditation and beyond

Directory of Open Access Journals (Sweden)

V Wadhwa

2012-01-01

Full Text Available This review attempts to clarify the concepts of Laboratory Quality Management System (Lab QMS for a medical testing and diagnostic laboratory in a holistic way and hopes to expand the horizon beyond quality control (QC and quality assurance. It provides an insight on accreditation bodies and highlights a glimpse of existing laboratory practices but essentially it takes the reader through the journey of accreditation and during the course of reading and understanding this document, prepares the laboratory for the same. Some of the areas which have not been highlighted previously include: requirement for accreditation consultants, laboratory infrastructure and scope, applying for accreditation, document preparation. This section is well supported with practical illustrations and necessary tables and exhaustive details like preparation of a standard operating procedure and a quality manual. Concept of training and privileging of staff has been clarified and a few of the QC exercises have been dealt with in a novel way. Finally, a practical advice for facing an actual third party assessment and caution needed to prevent post-assessment pitfalls has been dealt with.

Exploring the links between quality assurance and laboratory resources. An audit-based study.

Science.gov (United States)

Singh, Navjeevan; Panwar, Aru; Masih, Vipin Fazal; Arora, Vinod K; Bhatia, Arati

2003-01-01

To investigate and rectify the problems related to Ziehl-Neelsen (Z-N) staining in a cytology laboratory in the context of quality assurance. An audit based quality assurance study of 1,421 patients with clinical diagnoses of tubercular lymphadenopathy who underwent fine needle aspiration cytology. Data from 8 months were audited (group 1). Laboratory practices related to selection of smears for Z-N staining were studied. A 2-step corrective measure based on results of the audit was introduced for 2 months (group 2). Results were subjected to statistical analysis using the chi 2 test. Of 1,172 patients in group 1,368 had diagnoses other than tuberculosis. Overall acid-fast bacillus (AFB) positivity was 42%. AFB positivity in 249 patients in group 2 was 89% (P assurance. Solving everyday problems can have far-reaching benefits for the performance of laboratory personnel, resources and work flow.

The Los Alamos universe: Using multimedia to promote laboratory capabilities

Energy Technology Data Exchange (ETDEWEB)

Kindel, J.

2000-03-01

This project consists of a multimedia presentation that explains the technological capabilities of Los Alamos National Laboratory. It takes the form of a human-computer interface built around the metaphor of the universe. The project is intended promote Laboratory capabilities to a wide audience. Multimedia is simply a means of communicating information through a diverse set of tools--be they text, sound, animation, video, etc. Likewise, Los Alamos National Laboratory is a collection of diverse technologies, projects, and people. Given the ample material available at the Laboratory, there are tangible benefits to be gained by communicating across media. This paper consists of three parts. The first section provides some basic information about the Laboratory, its mission, and its needs. The second section introduces this multimedia presentation and the metaphor it is based on along with some basic concepts of color and user interaction used in the building of this project. The final section covers construction of the project, pitfalls, and future improvements.

Student perceptions of the clinical laboratory science profession.

Science.gov (United States)

McClure, Karen

2009-01-01

The purpose of this paper is to describe the attitudes and perceptions among college biology and CLS/CLT students. These students were on selected college campuses at Texas universities in Houston, Dallas and the Austin/San Antonio areas for the Spring 2007 semester. Specifically, students were questioned on factors that influence their choice of field of study, career expectations, legislative measures which might be used to attract individuals to the career, and factors that will be required to keep them in the field of practice. This study was part of a larger qualitative study which included exploratory discovery and inductive logic regarding the attitudes of four focus groups in Texas. Focus groups took place on college campuses or in hotel conference rooms. (1) junior/senior-level college biology students and (2) junior/senior-level students currently enrolled in CLS/CLT programs. Focus group discussions using a standard set of questions; group sessions lasted about 45 minutes. This study was a qualitative study which included exploratory discovery and inductive logic regarding the attitudes of two groups in Texas. College biology and CLS/CLT students find the clinical laboratory science profession to be interesting and exciting as a career prospect, however, many do not see themselves remaining in the profession and perceive it does not have good prospects for career advancement. The majority of students must work to support themselves through their college education and would welcome additional grants, scholarships and loan forgiveness programs as incentives to study the clinical laboratory sciences. Students believe that additional recruitment on high school and college campuses is needed to increase the visibility of the field as career choice. The majority of students who are entering the clinical laboratory science profession do not see the profession as their final career choice, but rather a stepping stone to another career field in healthcare or a

Study of embryotoxic effects of intranasally administred desloratadine on laboratory animals

Directory of Open Access Journals (Sweden)

Alekhina Т.А.

2017-04-01

Full Text Available The study was conducted to detect possible changes in embryogenesis and negative effects of third generation antihistamine – desloratadine – after intranasal administration of 1.3 mg/m3 and 13.0 mg/m3 of the substance to laboratory animals during their prenatal period. In these circumstances, desloratadine does not cause any significant changes of embryogenesis parameters. Macroscopic examination of the fetus and placenta in animals of experimental groups did not reveal any pathology or physiological deviations from the norm. 13.0 mg/m3 concentration of the drug caused a decrease in the weight of embryos in comparison with control group of animals and physiological data, despite a well developed, without visible pathology, placenta. This neces­sitates an in-depth study of possible teratogenic effects of intranasally administred desloratadine to laboratory animals.

Cost-price estimation of clinical laboratory services based on activity-based costing: A case study from a developing country.

Science.gov (United States)

Mouseli, Ali; Barouni, Mohsen; Amiresmaili, Mohammadreza; Samiee, Siamak Mirab; Vali, Leila

2017-04-01

It is believed that laboratory tariffs in Iran don't reflect the real costs. This might expose private laboratories at financial hardship. Activity Based Costing is widely used as a cost measurement instrument to more closely approximate the true cost of operations. This study aimed to determine the real price of different clinical tests of a selected private clinical laboratory. This study was a cross sectional study carried out in 2015. The study setting was the private laboratories in the city of Kerman, Iran. Of 629 tests in the tariff book of the laboratory (relative value), 188 tests were conducted in the laboratory that used Activity Based Costing (ABC) methodology to estimate cost-price. Analyzing and cost-price estimating of laboratory services were performed by MY ABCM software Version 5.0. In 2015, the total costs were $641,645. Direct and indirect costs were 78.3% and 21.7% respectively. Laboratory consumable costs by 37% and personnel costs by 36.3% had the largest share of the costing. Also, group of hormone tests cost the most $147,741 (23.03%), and other tests group cost the least $3,611 (0.56%). Also after calculating the cost of laboratory services, a comparison was made between the calculated price and the private sector's tariffs in 2015. This study showed that there was a difference between costs and tariffs in the private laboratory. One way to overcome this problem is to increase the number of laboratory tests with regard to capacity of the laboratories.

Studying Human Disease Genes in "Caenorhabditis Elegans": A Molecular Genetics Laboratory Project

Science.gov (United States)

Cox-Paulson, Elisabeth A.; Grana, Theresa M.; Harris, Michelle A.; Batzli, Janet M.

2012-01-01

Scientists routinely integrate information from various channels to explore topics under study. We designed a 4-wk undergraduate laboratory module that used a multifaceted approach to study a question in molecular genetics. Specifically, students investigated whether "Caenorhabditis elegans" can be a useful model system for studying genes…

D and D of a plutonium research laboratory and related auxiliary systems

International Nuclear Information System (INIS)

Diaz Arocas, P.; Martinez Ortega, A.; Sama Colao, J.; Garcia Diaz, A.; Torre Rodriguez, J.; Diaz Diaz, J.L.; Argiles, E.; Garrido, C.

2010-01-01

CIEMAT, former Junta de Energia Nuclear (JEN) started nuclear research at the 60. decade, focussed on the development of pacific uses of Nuclear Energy. At that time, CIEMAT research and pilot plants developed involved the whole nuclear fuel cycle steps. It means from the uranium recovery to the spent fuel reprocessing. With this scope a plutonium research laboratory was constructed and operated from 1961 to the 90's focussed on chemistry of plutonium studies, separation processes and radiochemical analyses, in order to assist the working pilot plants at the Centre. Thereafter, as the result of the changes on the research objectives of CIEMAT, the plutonium laboratory suffered several modifications and finally it was safety stopped due to the obsolescence of its equipments and auxiliary systems. Present paper shows the D and D activities performed and techniques developed to avoid alpha emitter contamination. In every dismantling phase there were established the measures of operational radiological protection adapted to the radiological risk. Dosimetric controls realized during dismantlement showed that incorporation of radionuclides was not detected. Radiological final control was performed applying the derived levels of declassification to request the installation decommissioning. (authors)

Introduction to Artificial Vision through Laboratory Guides Using Matlab

Directory of Open Access Journals (Sweden)

Verónica Londoño-Osorio

2013-11-01

Full Text Available This paper presents the design of two laboratory guides in artificial vision for a course which aims to introduce students to the different areas of specialization of his career. Therefore, the designed practices motivate and provide relevant content to the student, and to encourage research in the area of image processing. The first guide presents an introductory practice that explores the basic commands for image processing by programming a GUI in Matlab, and a second practice in which you use an image recognition algorithm, which compares the color characteristics of facial or objects images. The discussion of the results, challenges and recommendations for the development of each practice session are explained. The survey answers of the students are displayed. This survey allows checking their level of acceptance for the design and content of practice and motivation to continue studying in the image processing area. Finally, comparisons with laboratory guides that were designed in other universities are made.

Final characterization report for the 104-B-1 Tritium Vault and 104-B-2 Tritium Laboratory

International Nuclear Information System (INIS)

Encke, D.B.; Harris, R.A.

1996-11-01

This report is a compilation of the characterization data collected from the 104-B-1 Tritium Vault and the 104-B-2 Trillium Laboratory. The characterization activities were organized and implemented to evaluate the radiological status and identify any hazardous materials. The data contained in this report reflects the current conditions and status of the 104-B-1 Tritium Vault and 104-B-2 Tritium Laboratory. This information is intended to be utilized in support of future building decontamination and demolition, to allow for proper disposal of the demolition debris as required by the Washington Administrative Code, WAC 173-303, the Hanford Site Solid Waste Acceptance Criteria, WHC-EP-0063, and the Environmental Restoration Disposal Facility Waste Acceptance Criteria, BHI-00139. Based on the historical information and facility inspections, the only hazardous materials sampling and analysis activities necessary were to identify lead paint and asbestos containing materials (ACM) in the 104-B-1 Tritium Vault and the 104-B-2 Tritium Laboratory. Asbestos samples were obtained from the outer boundary of the roof areas to confirm the presence and type of asbestos containing fibers. Lead paint samples were obtained to confirm the presence and quantity of lead paint on the roof trim, doors and vents

Students' perceptions of academic dishonesty in a chemistry classroom laboratory

Science.gov (United States)

Del Carlo, Dawn Irene

Academic dishonesty has been an important issue in the classroom for as long as the classroom has been in use. Most reports pertain to exams, homework, and plagiarism of term papers but, one area that has not been studied extensively is that of the classroom laboratory. My work focuses on three guiding questions: (1) What are students' perceptions toward academic dishonesty in a laboratory based class? (2) What distinction if any do students make between this type of academic dishonesty compared to dishonesty that may occur in a research laboratory? (3) How if at all do these perceptions change with age and/or research experience? Four major assertions come from this work. The first is that students do not think that what they do in the classroom laboratory is science and consequently do not treat the classroom laboratory differently than any other academic class. Additionally, they make a clear distinction between what happens in a class lab and what happens in a research or industrial lab. Consequently, students perceive there to be a significant difference in dishonesty between those two settings. Finally, this distinction is not as pronounced in graduate students and is seen as an element of maturity. In the process of determining the above assertions, students perceptions on the nature of science were revealed and are also discussed. These beliefs have direct relevance to students' perceptions of dishonesty in both lab atmospheres.

Shop for quality or quantity? Volumes and costs in clinical laboratories.

Science.gov (United States)

Barletta, Giovanni; Zaninotto, Martina; Faggian, Diego; Plebani, Mario

2013-02-01

The increasing need to reduce the costs of providing diagnostic laboratory services has prompted initiatives based on the centralization and consolidation of laboratory facilities. However, the majority of papers and experiences reported in literature focus on "cost per test" thus overlooking the real value of a laboratory service, which requires more complex economic evaluations, such as cost-benefit, cost-effectiveness, and cost-utility analysis. It is important to perform cost analysis, which is no mean feat, by taking into consideration all variables affecting the final and true cost per test. The present study was conducted in order to evaluate the costs of delivering laboratory services in 20 Italian clinical laboratories using a widely accepted methodology, the so-called "activity-based costing analysis". The finding of a trend towards a decrease in total costs - due to an increase in test volumes - attained statistical significance only for quantities of up to about 1,100,00 tests per year. For 1,800,00 tests and more, the cost per test appeared to range from 1.5 to 2.0 € irrespective of the different volumes. Regarding the relationship between volumes and number of staff, there is an evident linear relationship between the number of senior staff and volumes, whereas this trend is not observed in the case of medical technologists, the degree and type of automation strongly affecting this variable. The findings made in the present study confirm that the relationship between volumes and costs is not linear; since it is complex, numerous variables should be taken into account.

Handbook of laboratory techniques

International Nuclear Information System (INIS)

2002-01-01

The Nuclear Regulatory Authority in Argentina have laboratories of support to regulations functions on radiological and nuclear safety, safeguards and physical protection, that have a surface of 2950 m 2 in the Ezeiza Atomic Center. The manual describes in seven chapters the different techniques developed and applied in the laboratories along four decades of existence. The chapter 1: Dedicated to the treatment of environmental samples, described the procedures associated with the different types of samples: deposits, waters, sediments, vegetables, milk, fish and diet. The chapter 2: Details 48 radiochemical techniques associated to the measurements of americium 241, carbon 16, strontium 90, iodine 129, plutonium, radium 226, radon, uranium, nickel and actinides. The chapter 3: Describes the measurements techniques of alpha and gamma spectrometry. The different techniques of biological and physical dosimetry are described in the chapters 5 and 6 respectively. The final chapter is dedicated the techniques of external and internal contamination. It s important to emphasize that this manual contains the standardized technologies that the Nuclear Regulatory Authority of Argentina submits regularly to international comparisons

Laboratory Astrophysics Prize: Laboratory Astrophysics with Nuclei

Science.gov (United States)

Wiescher, Michael

2018-06-01

Nuclear astrophysics is concerned with nuclear reaction and decay processes from the Big Bang to the present star generation controlling the chemical evolution of our universe. Such nuclear reactions maintain stellar life, determine stellar evolution, and finally drive stellar explosion in the circle of stellar life. Laboratory nuclear astrophysics seeks to simulate and understand the underlying processes using a broad portfolio of nuclear instrumentation, from reactor to accelerator from stable to radioactive beams to map the broad spectrum of nucleosynthesis processes. This talk focuses on only two aspects of the broad field, the need of deep underground accelerator facilities in cosmic ray free environments in order to understand the nucleosynthesis in stars, and the need for high intensity radioactive beam facilities to recreate the conditions found in stellar explosions. Both concepts represent the two main frontiers of the field, which are being pursued in the US with the CASPAR accelerator at the Sanford Underground Research Facility in South Dakota and the FRIB facility at Michigan State University.

Laboratory studies of dissolved radiolabelled microcystin-LR in lake water

DEFF Research Database (Denmark)

Hyenstrand, Per; Rohrlack, Thomas; Beattie, Kenneth A

2003-01-01

The fate of dissolved microcystin-LR was studied in laboratory experiments using surface water taken from a eutrophic lake. Based on initial range finding, a concentration of 50 microg l(-1) dissolved 14C-microcystin-LR was selected for subsequent time-course experiments. The first was performed ...... fractions. The study demonstrated that biodegradation of dissolved microcystin-LR occurred in water collected at a lake surface with carbon dioxide as a major end-product....

Laboratory technology research - abstracts of FY 1997 projects

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-11-01

The Laboratory Technology Research (LTR) program supports high-risk, multidisciplinary research partnerships to investigate challenging scientific problems whose solutions have promising commercial potential. These partnerships capitalize on two great strengths of this country: the world-class basic research capability of the DOE Energy Research (ER) multi-program national laboratories and the unparalleled entrepreneurial spirit of American industry. A distinguishing feature of the ER multi-program national laboratories is their ability to integrate broad areas of science and engineering in support of national research and development goals. The LTR program leverages this strength for the Nation`s benefit by fostering partnerships with US industry. The partners jointly bring technology research to a point where industry or the Department`s technology development programs can pursue final development and commercialization. Projects supported by the LTR program are conducted by the five ER multi-program laboratories. These projects explore the applications of basic research advances relevant to DOE`s mission over a full range of scientific disciplines. The program presently emphasizes three critical areas of mission-related research: advanced materials; intelligent processing/manufacturing research; and sustainable environments.

Facilitating Improvements in Laboratory Report Writing Skills with Less Grading: A Laboratory Report Peer-Review Process

Directory of Open Access Journals (Sweden)

Jennifer R. Brigati

2015-02-01

Full Text Available Incorporating peer-review steps in the laboratory report writing process provides benefits to students, but it also can create additional work for laboratory instructors. The laboratory report writing process described here allows the instructor to grade only one lab report for every two to four students, while giving the students the benefits of peer review and prompt feedback on their laboratory reports. Here we present the application of this process to a sophomore level genetics course and a freshman level cellular biology course, including information regarding class time spent on student preparation activities, instructor preparation, prerequisite student knowledge, suggested learning outcomes, procedure, materials, student instructions, faculty instructions, assessment tools, and sample data. T-tests comparing individual and group grading of the introductory cell biology lab reports yielded average scores that were not significantly different from each other (p = 0.13, n = 23 for individual grading, n = 6 for group grading. T-tests also demonstrated that average laboratory report grades of students using the peer-review process were not significantly different from those of students working alone (p = 0.98, n = 9 for individual grading, n = 6 for pair grading. While the grading process described here does not lead to statistically significant gains (or reductions in student learning, it allows student learning to be maintained while decreasing instructor workload. This reduction in workload could allow the instructor time to pursue other high-impact practices that have been shown to increase student learning. Finally, we suggest possible modifications to the procedure for application in a variety of settings.

Facilitating improvements in laboratory report writing skills with less grading: a laboratory report peer-review process.

Science.gov (United States)

Brigati, Jennifer R; Swann, Jerilyn M

2015-05-01

Incorporating peer-review steps in the laboratory report writing process provides benefits to students, but it also can create additional work for laboratory instructors. The laboratory report writing process described here allows the instructor to grade only one lab report for every two to four students, while giving the students the benefits of peer review and prompt feedback on their laboratory reports. Here we present the application of this process to a sophomore level genetics course and a freshman level cellular biology course, including information regarding class time spent on student preparation activities, instructor preparation, prerequisite student knowledge, suggested learning outcomes, procedure, materials, student instructions, faculty instructions, assessment tools, and sample data. T-tests comparing individual and group grading of the introductory cell biology lab reports yielded average scores that were not significantly different from each other (p = 0.13, n = 23 for individual grading, n = 6 for group grading). T-tests also demonstrated that average laboratory report grades of students using the peer-review process were not significantly different from those of students working alone (p = 0.98, n = 9 for individual grading, n = 6 for pair grading). While the grading process described here does not lead to statistically significant gains (or reductions) in student learning, it allows student learning to be maintained while decreasing instructor workload. This reduction in workload could allow the instructor time to pursue other high-impact practices that have been shown to increase student learning. Finally, we suggest possible modifications to the procedure for application in a variety of settings.

Facilitating Improvements in Laboratory Report Writing Skills with Less Grading: A Laboratory Report Peer-Review Process†

Science.gov (United States)

Brigati, Jennifer R.; Swann, Jerilyn M.

2015-01-01

Incorporating peer-review steps in the laboratory report writing process provides benefits to students, but it also can create additional work for laboratory instructors. The laboratory report writing process described here allows the instructor to grade only one lab report for every two to four students, while giving the students the benefits of peer review and prompt feedback on their laboratory reports. Here we present the application of this process to a sophomore level genetics course and a freshman level cellular biology course, including information regarding class time spent on student preparation activities, instructor preparation, prerequisite student knowledge, suggested learning outcomes, procedure, materials, student instructions, faculty instructions, assessment tools, and sample data. T-tests comparing individual and group grading of the introductory cell biology lab reports yielded average scores that were not significantly different from each other (p = 0.13, n = 23 for individual grading, n = 6 for group grading). T-tests also demonstrated that average laboratory report grades of students using the peer-review process were not significantly different from those of students working alone (p = 0.98, n = 9 for individual grading, n = 6 for pair grading). While the grading process described here does not lead to statistically significant gains (or reductions) in student learning, it allows student learning to be maintained while decreasing instructor workload. This reduction in workload could allow the instructor time to pursue other high-impact practices that have been shown to increase student learning. Finally, we suggest possible modifications to the procedure for application in a variety of settings. PMID:25949758

PLACE: an open-source python package for laboratory automation, control, and experimentation.

Science.gov (United States)

Johnson, Jami L; Tom Wörden, Henrik; van Wijk, Kasper

2015-02-01

In modern laboratories, software can drive the full experimental process from data acquisition to storage, processing, and analysis. The automation of laboratory data acquisition is an important consideration for every laboratory. When implementing a laboratory automation scheme, important parameters include its reliability, time to implement, adaptability, and compatibility with software used at other stages of experimentation. In this article, we present an open-source, flexible, and extensible Python package for Laboratory Automation, Control, and Experimentation (PLACE). The package uses modular organization and clear design principles; therefore, it can be easily customized or expanded to meet the needs of diverse laboratories. We discuss the organization of PLACE, data-handling considerations, and then present an example using PLACE for laser-ultrasound experiments. Finally, we demonstrate the seamless transition to post-processing and analysis with Python through the development of an analysis module for data produced by PLACE automation. © 2014 Society for Laboratory Automation and Screening.

Point-of-Care Test Equipment for Flexible Laboratory Automation.

Science.gov (United States)

You, Won Suk; Park, Jae Jun; Jin, Sung Moon; Ryew, Sung Moo; Choi, Hyouk Ryeol

2014-08-01

Blood tests are some of the core clinical laboratory tests for diagnosing patients. In hospitals, an automated process called total laboratory automation, which relies on a set of sophisticated equipment, is normally adopted for blood tests. Noting that the total laboratory automation system typically requires a large footprint and significant amount of power, slim and easy-to-move blood test equipment is necessary for specific demands such as emergency departments or small-size local clinics. In this article, we present a point-of-care test system that can provide flexibility and portability with low cost. First, the system components, including a reagent tray, dispensing module, microfluidic disk rotor, and photometry scanner, and their functions are explained. Then, a scheduler algorithm to provide a point-of-care test platform with an efficient test schedule to reduce test time is introduced. Finally, the results of diagnostic tests are presented to evaluate the system. © 2014 Society for Laboratory Automation and Screening.

Results of a comparative study on insulin radioimmunoassay in 36 Italian laboratories

Energy Technology Data Exchange (ETDEWEB)

Costantini, A; Lostia, O; Malvano, R; Rolleri, E; Taggi, F; Zucchelli, G C [Istituto Superiore di Sanita, Rome (Italy); Consiglio Nazionale delle Ricerche, Pisa (Italy))

1975-12-01

An interlaboratory study in which the insulin contents of five plasma samples were estimated in 36 italian laboratories was coordinated by the Istituto Superiore di Sanita (National Institute of Health) and the Consiglio Nazionale delle Ricerche (National Research Council). A rather large between-laboratory variability resulted, though the ranking of samples according to their insulin concentrations was practically the same. A significant dependence of estimates on the method used was established. The analysis of data aimed at defining the possible reasons of the assay variability is reported and discussed.

Considerations for services from dental technicians in fabrication of fixed prostheses: A survey of commercial dental laboratories in Thessaloniki, Greece.

Science.gov (United States)

Hatzikyriakos, Andreas; Petridis, Haralampos P; Tsiggos, Nikolaos; Sakelariou, Sotirios

2006-11-01

Effective communication and cooperation between dentists and dental technicians are essential in providing quality services. There has been a lack of information regarding dentist-dental technician communications and current methods and materials used for the fabrication of fixed partial dentures (FPDs). This cross-sectional study identified the materials and techniques used for fabrication of FPDs, as well as the status of communication between dentists and dental technicians in Thessaloniki, Greece. A questionnaire was developed with 7 sections pertaining to procedures and materials used for the fabrication of fixed prostheses: general questions, infection control, impressions/interocclusal records, die technique/mounting, information from final casts, prostheses design/materials, and communication/shade selection. The questionnaire was anonymous and distributed by the Association of Dental Technicians of Thessaloniki to all member laboratories (228) in the wider province of Thessaloniki, Greece. Due to the absence of normal distribution of the results, frequencies and medians were reported. Ninety-six of 228 dental laboratories responded (42.1% response rate). Twenty-six percent of dental laboratories did not routinely disinfect incoming items. The dental technicians considered 30% of incoming final impressions and 20% of interocclusal registrations as inadequate. Half of the time (55%) final casts were mounted by technicians on simple hinge articulators. Only 20% of tooth preparations had adequate finish lines. The majority (70%) of fixed restorations were metal-ceramic. Fifty-seven percent of dental technicians considered the delivery time requested by dentists as insufficient. The information provided in this study indicates areas of weakness in communication between dentists and dental technicians, along with areas where both parties should use greater care during clinical and laboratory procedures.

Modern clinical laboratory diagnostics

International Nuclear Information System (INIS)

Balakhovskij, I.S.

1986-01-01

Laboratory diagnosis is auxillary medical discipline studying specific laboratory symptoms of diseases, revealed by investigations of materials taken from patients. The structure of laboratory servie in our country and abroad, items of laboratory investigations, organizational principles are described. Attention is being given to the cost of analyses, the amount of conducted investigations, methods of result presentation, problems of accuracy, quality control and information content

Laboratory Studies Of Astrophysically-interesting Phosphorus-bearing Molecules

Science.gov (United States)

Ziurys, Lucy M.; Halfen, D. T.; Sun, M.; Clouthier, D. J.

2009-05-01

Over the past year, there has been a renewed interest in the presence of phosphorus-containing molecules in the interstellar medium. Recent observations have increased the number of known interstellar phosphorus-bearing species from two (PN, CP) to six with the identification of HCP, CCP, and PH3 in the carbon-rich circumstellar shell of IRC+10216 and PO in the oxygen-rich envelope of VY Canis Majoris. More species of this type may be present in the ISM, but laboratory rest frequencies, necessary for such detections, are not generally known for many potential molecules. To fill in this gap, we have been conducting measurements of the pure rotational spectra of phosphorus-containing molecules of astrophysical interest, using both millimeter/submm direct absorption and Fourier transform microwave (FTMW) spectroscopy. We have developed a new phosphorus source for this purpose. These methods cover the frequency ranges 65-850 GHz and 4-40 GHz, respectively. Our recent study of the CCP radical (X2Πr) using both of these techniques has resulted in its identification in IRC+10216. Rotational spectra of other molecules such as PCN, HPS, and CH3PH2 have been recorded. We will report on these species and additional new laboratory developments

Decommissioning of the radio chemical hot laboratory of the european commission joint research centre of Ispra - 59207

International Nuclear Information System (INIS)

Ugolini, Daniele; Rossi, Francesco; Basile, Francesco

2012-01-01

The construction of the Radio Chemical Hot Laboratory (RCHL) of the Joint Research Centre (JRC) of Ispra began in the early 1960's while the laboratory activities started in 1964. In 1976 an annex to the main building was built. At this time the RCHL main research activities were in environment and biochemistry by means of radioactive tracers; neutron activation analyses; extraction of actinides from radioactive liquid waste coming from the nuclear fuel reprocessing plants; and analyses of U, Pu, and Th in samples from the nuclear fuel cycle in order to determine the isotopic ratio and the burn-up. In 1978, a new area of laboratories named 'Stabularium' was built to study the metabolism of heavy metal on laboratory animals. Complementary to the laboratory three pneumatic transfer systems for irradiated sources connected the RCHL to two research reactors. The decommissioning activities of the 2650 m 2 facility started in January 2008 and they were completed at the end of 2010 with the release for unrestricted use of all the buildings of the facility. They consisted in five main tasks: pre-decommissioning, licensing, dismantling, waste management, and final survey. The main pre-decommissioning activities were the physical and radiological characterization of the facility. The principal licensing activity was the preparation of the de-licensing documentation to obtain the license termination from the safety authorities. Dismantling consisted in the removal of all the equipments and ancillary systems, of the pneumatic transfer system, and in the decontamination of the structures of the controlled zone. The waste management was limited to the transfer of the waste and of the clearable material to the centralized waste management facility. The final survey consisted in the final radiological characterization to quantify the concentration of any residual radioactivity remained after the completion of the dismantling activities for the release of the RCHL without any

Aespoe hard rock laboratory Sweden

International Nuclear Information System (INIS)

1992-01-01

The aim of the new Aespoe hard rock laboratory is to demonstrate state of the art of technology and evaluation methods before the start of actual construction work on the planned deep repository for spent nuclear fuel. The nine country OECD/NEA project in the Stripa mine in Sweden has been an excellent example of high quality international research co-operation. In Sweden the new Aespoe hard rock laboratory will gradually take over and finalize this work. SKB very much appreciates the continued international participation in Aespoe which is of great value for the quality efficiency, and confidence in this kind of work. We have invited a number of leading experts to this first international seminar to summarize the current state of a number of key questions. The contributions show the great progress that has taken place during the years. The results show that there is a solid scientific basis for using this knowledge on site specific preparation and work on actual repositories. (au)

Oil water laboratory

International Nuclear Information System (INIS)

P Junior, Oswaldo A.; Verli, Fernando; Lopes, Humberto E.

2000-01-01

Usually, the oily water effluent from petroleum processes needs to be treated prior to its environment discard and/or reuse. The synthesis of such water effluent residues in an Oily Water Laboratory - equipped with Water Treatment Pilot Scale Units - is fundamental to the study and effectiveness comparison among the typical industrial water treatment processes. The Oily Water Laboratory will allow the reproduction - in a small scale - of any oily water effluent produced in the industrial PETROBRAS units - such reproduction can be obtained by using the same fluids, oily concentration, salinity, process temperature, particle size distribution etc. Such Laboratory also allows the performance analysis of typical industrial equipment used throughout the water treatment schemes (e.g., hydro-cyclones), resulting in design and/or operational guidelines for these industrial scale schemes. In the particular niche of very small diameter oil droplet removal, more efficient and non-conventional schemes - such as centrifuges and/or membrane filtration - will be also studied in the Laboratory. In addition, the Laboratory shall be used in the certification of in-line oily water analyzers (e.g., TOC - Total Organic Carbon and OWC - Oil Wax Content). This paper describes the characteristics of such Laboratory and its main operational philosophy. (author)

Diagnostic and laboratory test ordering in Northern Portuguese Primary Health Care: a cross-sectional study

Science.gov (United States)

Sá, Luísa; Teixeira, Andreia Sofia Costa; Tavares, Fernando; Costa-Santos, Cristina; Couto, Luciana; Costa-Pereira, Altamiro; Hespanhol, Alberto Pinto; Santos, Paulo

2017-01-01

Objectives To characterise the test ordering pattern in Northern Portugal and to investigate the influence of context-related factors, analysing the test ordered at the level of geographical groups of family physicians and at the level of different healthcare organisations. Design Cross-sectional study. Setting Northern Primary Health Care, Portugal. Participants Records about diagnostic and laboratory tests ordered from 2035 family physicians working at the Northern Regional Health Administration, who served approximately 3.5 million Portuguese patients, in 2014. Outcomes To determine the 20 most ordered diagnostic and laboratory tests in the Northern Regional Health Administration; to identify the presence and extent of variations in the 20 most ordered diagnostic and laboratory tests between the Groups of Primary Care Centres and between health units; and to study factors that may explain these variations. Results The 20 most ordered diagnostic and laboratory tests almost entirely comprise laboratory tests and account for 70.9% of the total tests requested. We can trace a major pattern of test ordering for haemogram, glucose, lipid profile, creatinine and urinalysis. There was a significant difference (P<0.001) in test orders for all tests between Groups of Primary Care Centres and for all tests, except glycated haemoglobin (P=0.06), between health units. Generally, the Personalised Healthcare Units ordered more than Family Health Units. Conclusions The results from this study show that the most commonly ordered tests in Portugal are laboratory tests, that there is a tendency for overtesting and that there is a large variability in diagnostic and laboratory test ordering in different geographical and organisational Portuguese primary care practices, suggesting that there may be considerable potential for the rationalisation of test ordering. The existence of Family Health Units seems to be a strong determinant in decreasing test ordering by Portuguese family

Radioisotope laboratory in Turkey

International Nuclear Information System (INIS)

1961-01-01

The Turkish Government formally requested that the Agency provide for one year the services of an expert in the agricultural applications of radioisotopes. Specifically, they wanted this expert first of all to assist in setting up and equipping a pioneer laboratory for the utilization of radioisotopes in agricultural research. Once the laboratory was in operation, the expert was to initiate various research projects using isotope techniques, and to train personnel to carry on this work. The Agency was also asked to supply various specialized equipment for the laboratory, including some radioisotopes. On 10 December 1960 the first phase was complete - the new laboratory was formally opened. It is foreseen that the research projects which will be initiated at the laboratory will include the following: determination of the effect of fertilizers upon yield and quality of field crops and fruit trees, soil fertility studies, studies of mineral element uptake and localization of nutrients in plant body, studies of the folar application of mineral nutrients, especially in fruit trees, investigation of microelements in field crops and fruit trees, investigation of pollination problems, study of the distribution of mineral elements in different fruit seedlings, study of the uptake of nutrients by fruit trees during the rest period, dispersal studies on insects, insecticide studies

Radioisotope laboratory in Turkey

Energy Technology Data Exchange (ETDEWEB)

NONE

1961-04-15

The Turkish Government formally requested that the Agency provide for one year the services of an expert in the agricultural applications of radioisotopes. Specifically, they wanted this expert first of all to assist in setting up and equipping a pioneer laboratory for the utilization of radioisotopes in agricultural research. Once the laboratory was in operation, the expert was to initiate various research projects using isotope techniques, and to train personnel to carry on this work. The Agency was also asked to supply various specialized equipment for the laboratory, including some radioisotopes. On 10 December 1960 the first phase was complete - the new laboratory was formally opened. It is foreseen that the research projects which will be initiated at the laboratory will include the following: determination of the effect of fertilizers upon yield and quality of field crops and fruit trees, soil fertility studies, studies of mineral element uptake and localization of nutrients in plant body, studies of the folar application of mineral nutrients, especially in fruit trees, investigation of microelements in field crops and fruit trees, investigation of pollination problems, study of the distribution of mineral elements in different fruit seedlings, study of the uptake of nutrients by fruit trees during the rest period, dispersal studies on insects, insecticide studies.

Final report of APMP.QM-S6: clenbuterol in porcine meat

Science.gov (United States)

Sin, D. W.-M.; Ho, C.; Yip, Y.-C.

2016-01-01

At the CCQM Organic Analysis Working Group (OAWG) Meeting held in April 2012 and the APMP TCQM Meeting held in November 2012, an APMP supplementary comparison (APMP.QM-S6) on the determination of clenbuterol in porcine meat was supported by the OAWG and APMP TCQM. This comparison was organized by the Government Laboratory, Hong Kong. In order to accommodate a wider participation, a pilot study (APMP.QM-P22) was run in parallel to APMP.QM-S6. This study provided the means for assessing the measurement capabilities for determination of low-polarity measurands in a procedure that requires extraction, clean-up, analytical separation, and selective detection in a food matrix. A total of 7 institutes registered for the supplementary comparison and 6 of them submitted their results. 4 results were included for SCRV calculation. All participating laboratories applied Isotope Dilution Liquid Chromatography-Tandem Mass Spectrometry (ID-LCMS/MS) technique with clenbuterol-d9 as internal standard spiked for quantitation in this programme. KEY WORDS FOR SEARCH APMP.QM-S6 and Clenbuterol Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Plan for advanced microelectronics processing technology application. Final report

Energy Technology Data Exchange (ETDEWEB)

Goland, A.N.

1990-10-01

The ultimate objective of the tasks described in the research agreement was to identify resources primarily, but not exclusively, within New York State that are available for the development of a Center for Advanced Microelectronics Processing (CAMP). Identification of those resources would enable Brookhaven National Laboratory to prepare a program plan for the CAMP. In order to achieve the stated goal, the principal investigators undertook to meet the key personnel in relevant NYS industrial and academic organizations to discuss the potential for economic development that could accompany such a Center and to gauge the extent of participation that could be expected from each interested party. Integrated of these discussions was to be achieved through a workshop convened in the summer of 1990. The culmination of this workshop was to be a report (the final report) outlining a plan for implementing a Center in the state. As events unfolded, it became possible to identify the elements of a major center for x-ray lithography on Lone Island at Brookhaven National Laboratory. The principal investigators were than advised to substitute a working document based upon that concept in place of a report based upon the more general CAMP workshop originally envisioned. Following that suggestion from the New York State Science and Technology Foundation, the principals established a working group consisting of representatives of the Grumman Corporation, Columbia University, the State University of New York at Stony Brook, and Brookhaven National Laboratory. Regular meetings and additional communications between these collaborators have produced a preproposal that constitutes the main body of the final report required by the contract. Other components of this final report include the interim report and a brief description of the activities which followed the establishment of the X-ray Lithography Center working group.

76 FR 50212 - Site-Wide Environmental Impact Statement for Sandia National Laboratories, New Mexico (SNL/NM)

Science.gov (United States)

2011-08-12

... Environmental Impact Statement for Sandia National Laboratories, New Mexico (DOE/EIS-0281-SA-04), DOE/NNSA... Environmental Impact Statement for Sandia National Laboratories, New Mexico for the Installation of a Petawatt..., New Mexico Final Supplement Analysis for the Site-Wide Environmental Impact Statement (2006 SNL/NM...

Good Laboratory Practice. Part 3. Implementing Good Laboratory Practice in the Analytical Lab

Science.gov (United States)

Wedlich, Richard C.; Pires, Amanda; Fazzino, Lisa; Fransen, Joseph M.

2013-01-01

Laboratories submitting experimental results to the Food and Drug Administration (FDA) or the Environmental Protection Agency (EPA) in support of Good Laboratory Practice (GLP) nonclinical laboratory studies must conduct such work in compliance with the GLP regulations. To consistently meet these requirements, lab managers employ a "divide…

Laboratory beam-plasma interactions linear and nonlinear

International Nuclear Information System (INIS)

Christiansen, P.J.; Bond, J.W.; Jain, V.K.

1982-01-01

This chapter attempts to demonstrate that despite unavoidable scaling limitations, laboratory experiments can uncover details of beam plasma interaction processes which could never be revealed through space plasma physics. Topics covered include linear theory, low frequency couplings, indirect effects, nonlinear effects, quasi-linear effects, trapping effects, nonlinear wave-wave interactions, and self modulation and cavitation. Unstable electrostatic waves arising from an exchange of energy with the ''free energy'' beam features are considered as kinetic and as hydrodynamic, or fluid, instabilities. The consequences of such instabilities (e.g. when the waves have grown to a finite level) are examined and some studies are reviewed which have attempted to understand how the free energy originally available in the beam is redistributed to produce a final state of equilibrium turbulence

Spacecraft fabrication and test MODIL. Final report

Energy Technology Data Exchange (ETDEWEB)

Saito, T.T.

1994-05-01

This report covers the period from October 1992 through the close of the project. FY 92 closed out with the successful briefing to industry and with many potential and important initiatives in the spacecraft arena. Due to the funding uncertainties, we were directed to proceed as if our funding would be approximately the same as FY 92 ($2M), but not to make any major new commitments. However, the MODIL`s FY 93 funding was reduced to $810K and we were directed to concentrate on the cryocooler area. The cryocooler effort completed its demonstration project. The final meetings with the cryocooler fabricators were very encouraging as we witnessed the enthusiastic reception of technology to help them reduce fabrication uncertainties. Support of the USAF Phillips Laboratory cryocooler program was continued including kick-off meetings for the Prototype Spacecraft Cryocooler (PSC). Under Phillips Laboratory support, Gill Cruz visited British Aerospace and Lucas Aerospace in the United Kingdom to assess their manufacturing capabilities. In the Automated Spacecraft & Assembly Project (ASAP), contracts were pursued for the analysis by four Brilliant Eyes prime contractors to provide a proprietary snap shot of their current status of Integrated Product Development. In the materials and structure thrust the final analysis was completed of the samples made under the contract (``Partial Automation of Matched Metal Net Shape Molding of Continuous Fiber Composites``) to SPARTA. The Precision Technologies thrust funded the Jet Propulsion Laboratory to prepare a plan to develop a Computer Aided Alignment capability to significantly reduce the time for alignment and even possibly provide real time and remote alignment capability of systems in flight.

Studies of relativistic heavy ion collisions. Final report, July 16, 1987-December 31, 1997

International Nuclear Information System (INIS)

Madansky, L.

1997-01-01

As a member of the DLS collaboration, the Hopkins group participated in all aspects of the experiment and the analysis of the results. The recent work involved measurements of dielectrons from p-p, p-d collisions as well as heavy ion Ca-Ca collisions at high densities. These results show the expected effects of bremsstrahlung vector meson decay and Dalitz decay but still show that some varieties of the low mass cross-sections disagree with various theoretical estimates, which could indicate other effects of high nuclear density. The Hopkins group has also been an initial member of the STAR collaboration and helped initiate the proposal for jet searches in the heavy ion experiments at RHIC. The group was instrumental in initiating the first stage of an electro-magnetic calorimeter for these experiments. The group also joined (E896) the Ho experiment. This work was primarily devoted to finding the existence of an elementary system containing strange quarks. An initial experiment was done recently at which Hopkins provided various beam counters. The final work is expected to commence in the fall of '98. Finally, the group has contributed to a number of experiments involving polarization effects in nuclear collisions, searching for production of antimatter, and other aspects of relativistic collisions of heavy ions using the facilities at Brookhaven National Laboratory (BNL)

Cross flow filtration of Oak Ridge National Laboratory liquid low-level waste

International Nuclear Information System (INIS)

Fowler, V.L.; Hewitt, J.D.

1989-12-01

A new method for disposal of Oak Ridge National Laboratory liquid low-level radioactive waste is being developed as an alternative to hydrofracture. The acceptability of the final waste form rests in part on the presence or absence of transuranic (TRU) isotopes. Inertial cross flow filtration was used in this study to determine the potential of this method for separation of the TRU isotopes from the bulk liquid stored in the Melton Valley Storage Tanks. 7 refs., 11 figs., 5 tabs

Matrix diffusion studies by electrical conductivity methods. Comparison between laboratory and in-situ measurements

International Nuclear Information System (INIS)

Ohlsson, Y.; Neretnieks, I.

1998-01-01

Traditional laboratory diffusion experiments in rock material are time consuming, and quite small samples are generally used. Electrical conductivity measurements, on the other hand, provide a fast means for examining transport properties in rock and allow measurements on larger samples as well. Laboratory measurements using electrical conductivity give results that compare well to those from traditional diffusion experiments. The measurement of the electrical resistivity in the rock surrounding a borehole is a standard method for the detection of water conducting fractures. If these data could be correlated to matrix diffusion properties, in-situ diffusion data from large areas could be obtained. This would be valuable because it would make it possible to obtain data very early in future investigations of potentially suitable sites for a repository. This study compares laboratory electrical conductivity measurements with in-situ resistivity measurements from a borehole at Aespoe. The laboratory samples consist mainly of Aespoe diorite and fine-grained granite and the rock surrounding the borehole of Aespoe diorite, Smaaland granite and fine-grained granite. The comparison shows good agreement between laboratory measurements and in-situ data

Securing America’s Future. Realizing the Potential of the Department of Energy’s National Laboratories

Energy Technology Data Exchange (ETDEWEB)

Glauthier, T. J. [TJG Energy Associates, LLC, Bloomberg, VA (United States); Cohon, Jared L. [Carnegie Mellon Univ., Pittsburgh, PA (United States); Augustine, Norman R. [U.S. Dept. of Homeland Security, Washington, DC (United States); Austin, Wanda M. [Aerospace Corporation, El Segundo, CA (United States); Elachi, Charles [California Inst. of Technology (CalTech), Pasadena, CA (United States); Fleury, Paul A. [Yale Univ., New Haven, CT (United States); Hockfield, Susan J. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Meserve, Richard A. [Covington and Burling LLP, Washington, DC (United States); Murray, Cherry A. [Harvard Univ., Cambridge, MA (United States)

2015-10-23

The Department of Energy (DOE) laboratories are national assets that have contributed profoundly to the Nation’s security, scientific leadership, and economic competitiveness. In recognition of the continuing and evolving threats to our security and the dramatic increase in global economic and scientific competition, the laboratories are and will continue to be vitally important. Yet, the contributions of the National Laboratories are not inevitable, nor have they realized their full potential. This final report of the Commission to Review the Effectiveness of the National Energy Laboratories recommends ways the laboratories could overcome challenges to more efficiently and effectively accomplish the work for which they are uniquely suited.

Procedures of Exercise Physiology Laboratories

Science.gov (United States)

Bishop, Phillip A.; Fortney, Suzanne; Greenisen, Michael; Siconolfi, Steven F.; Bamman, Marcas M.; Moore, Alan D., Jr.; Squires, William

1998-01-01

This manual describes the laboratory methods used to collect flight crew physiological performance data at the Johnson Space Center. The Exercise Countermeasures Project Laboratory is a standard physiology laboratory; only the application to the study of human physiological adaptations to spaceflight is unique. In the absence of any other recently published laboratory manual, this manual should be a useful document staffs and students of other laboratories.

Automating the Analytical Laboratories Section, Lewis Research Center, National Aeronautics and Space Administration: a feasibility study

International Nuclear Information System (INIS)

Boyle, W.G.; Barton, G.W.

1979-01-01

We studied the feasibility of computerized automation of the Analytical Laboratories Section at NASA's Lewis Research Center. Since that laboratory's duties are not routine, we set our automation goals with that in mind. We selected four instruments as the most likely automation candidates: an atomic absorption spectrophotometer, an emission spectrometer, an x-ray fluorescence spectrometer, and an x-ray diffraction unit. Our study describes two options for computer automation: a time-shared central computer and a system with microcomputers for each instrument connected to a central computer. A third option, presented for future planning, expands the microcomputer version. We determine costs and benefits for each option. We conclude that the microcomputer version best fits the goals and duties of the laboratory and that such an automated system is needed to meet the laboratory's future requirements

Determination of Soil Moisture Content using Laboratory Experimental and Field Electrical Resistivity Values

Science.gov (United States)

Hazreek, Z. A. M.; Rosli, S.; Fauziah, A.; Wijeyesekera, D. C.; Ashraf, M. I. M.; Faizal, T. B. M.; Kamarudin, A. F.; Rais, Y.; Dan, M. F. Md; Azhar, A. T. S.; Hafiz, Z. M.

2018-04-01

The efficiency of civil engineering structure require comprehensive geotechnical data obtained from site investigation. In the past, conventional site investigation was heavily related to drilling techniques thus suffer from several limitations such as time consuming, expensive and limited data collection. Consequently, this study presents determination of soil moisture content using laboratory experimental and field electrical resistivity values (ERV). Field and laboratory electrical resistivity (ER) test were performed using ABEM SAS4000 and Nilsson400 soil resistance meter. Soil sample used for resistivity test was tested for characterization test specifically on particle size distribution and moisture content test according to BS1377 (1990). Field ER data was processed using RES2DINV software while laboratory ER data was analyzed using SPSS and Excel software. Correlation of ERV and moisture content shows some medium relationship due to its r = 0.506. Moreover, coefficient of determination, R2 analyzed has demonstrate that the statistical correlation obtain was very good due to its R2 value of 0.9382. In order to determine soil moisture content based on statistical correlation (w = 110.68ρ-0.347), correction factor, C was established through laboratory and field ERV given as 19.27. Finally, this study has shown that soil basic geotechnical properties with particular reference to water content was applicably determined using integration of laboratory and field ERV data analysis thus able to compliment conventional approach due to its economic, fast and wider data coverage.

Road Transportable Analytical Laboratory (RTAL) system

International Nuclear Information System (INIS)

Finger, S.M.

1995-01-01

U.S. Department of Energy (DOE) facilities around the country have, over the years, become contaminated with radionuclides and a range of organic and inorganic wastes. Many of the DOE sites encompass large land areas and were originally sited in relatively unpopulated regions of the country to minimize risk to surrounding populations. In addition, wastes were sometimes stored underground at the sites in 55-gallon drums, wood boxes or other containers until final disposal methods could be determined. Over the years, these containers have deteriorated, releasing contaminants into the surrounding environment. This contamination has spread, in some cases polluting extensive areas. Remediation of these sites requires extensive sampling to determine the extent of the contamination, to monitor clean-up and remediation progress, and for post-closure monitoring of facilities. The DOE would benefit greatly if it had reliable, road transportable, fully independent laboratory systems that could perform on-site the full range of analyses required. Such systems would accelerate and thereby reduce the cost of clean-up and remediation efforts by (1) providing critical analytical data more rapidly, and (2) eliminating the handling, shipping and manpower associated with sample shipments. The goal of the Road Transportable Analytical Laboratory (RTAL) Project is the development and demonstration of a system to meet the unique needs of the DOE for rapid, accurate analysis of a wide variety of hazardous and radioactive contaminants in soil, groundwater, and surface waters. This laboratory system has been designed to provide the field and laboratory analytical equipment necessary to detect and quantify radionuclides, organics, heavy metals and other inorganic compounds. The laboratory system consists of a set of individual laboratory modules deployable independently or as an interconnected group to meet each DOE site's specific needs

Hot Laboratories and Remote Handling

International Nuclear Information System (INIS)

2007-01-01

The Opening talk of the workshop 'Hot Laboratories and Remote Handling' was given by Marin Ciocanescu with the communication 'Overview of R and D Program in Romanian Institute for Nuclear Research'. The works of the meeting were structured into three sections addressing the following items: Session 1. Hot cell facilities: Infrastructure, Refurbishment, Decommissioning; Session 2. Waste, transport, safety and remote handling issues; Session 3. Post-Irradiation examination techniques. In the frame of Section 1 the communication 'Overview of hot cell facilities in South Africa' by Wouter Klopper, Willie van Greunen et al, was presented. In the framework of the second session there were given the following four communications: 'The irradiated elements cell at PHENIX' by Laurent Breton et al., 'Development of remote equipment for DUPIC fuel fabrication at KAERI', by Jung Won Lee et al., 'Aspects of working with manipulators and small samples in an αβγ-box, by Robert Zubler et al., and 'The GIOCONDA experience of the Joint Research Centre Ispra: analysis of the experimental assemblies finalized to their safe recovery and dismantling', by Roberto Covini. Finally, in the framework of the third section the following five communications were presented: 'PIE of a CANDU fuel element irradiated for a load following test in the INR TRIGA reactor' by Marcel Parvan et al., 'Adaptation of the pole figure measurement to the irradiated items from zirconium alloys' by Yury Goncharenko et al., 'Fuel rod profilometry with a laser scan micrometer' by Daniel Kuster et al., 'Raman spectroscopy, a new facility at LECI laboratory to investigate neutron damage in irradiated materials' by Lionel Gosmain et al., and 'Analysis of complex nuclear materials with the PSI shielded analytical instruments' by Didier Gavillet. In addition, eleven more presentations were given as posters. Their titles were: 'Presentation of CETAMA activities (CEA analytic group)' by Alain Hanssens et al. 'Analysis of

The Effect of Guided-Inquiry Laboratory Experiments on Science Education Students' Chemistry Laboratory Attitudes, Anxiety and Achievement

Science.gov (United States)

Ural, Evrim

2016-01-01

The study aims to search the effect of guided inquiry laboratory experiments on students' attitudes towards chemistry laboratory, chemistry laboratory anxiety and their academic achievement in the laboratory. The study has been carried out with 37 third-year, undergraduate science education students, as a part of their Science Education Laboratory…

Variability in baseline laboratory measurements of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).

Science.gov (United States)

Ladwig, R; Vigo, A; Fedeli, L M G; Chambless, L E; Bensenor, I; Schmidt, M I; Vidigal, P G; Castilhos, C D; Duncan, B B

2016-08-01

Multi-center epidemiological studies must ascertain that their measurements are accurate and reliable. For laboratory measurements, reliability can be assessed through investigation of reproducibility of measurements in the same individual. In this paper, we present results from the quality control analysis of the baseline laboratory measurements from the ELSA-Brasil study. The study enrolled 15,105 civil servants at 6 research centers in 3 regions of Brazil between 2008-2010, with multiple biochemical analytes being measured at a central laboratory. Quality control was ascertained through standard laboratory evaluation of intra- and inter-assay variability and test-retest analysis in a subset of randomly chosen participants. An additional sample of urine or blood was collected from these participants, and these samples were handled in the same manner as the original ones, locally and at the central laboratory. Reliability was assessed with the intraclass correlation coefficient (ICC), estimated through a random effects model. Coefficients of variation (CV) and Bland-Altman plots were additionally used to assess measurement variability. Laboratory intra and inter-assay CVs varied from 0.86% to 7.77%. From test-retest analyses, the ICCs were high for the majority of the analytes. Notably lower ICCs were observed for serum sodium (ICC=0.50; 95%CI=0.31-0.65) and serum potassium (ICC=0.73; 95%CI=0.60-0.83), due to the small biological range of these analytes. The CVs ranged from 1 to 14%. The Bland-Altman plots confirmed these results. The quality control analyses showed that the collection, processing and measurement protocols utilized in the ELSA-Brasil produced reliable biochemical measurements.

Can post-eradication laboratory containment of wild polioviruses be achieved?

Science.gov (United States)

Dowdle, Walter R.; Gary, Howard E.; Sanders, Raymond; van Loon, Anton M.

2002-01-01

The purpose of containment is to prevent reintroduction of wild polioviruses from laboratories into polio-free communities. In order to achieve global commitment to laboratory containment the rationale should be clear and compelling; the biosafety levels should be justified by the risks; and the objectives should be realistic. Absolute containment can never be assured. Questions of intentional or unintentional non-compliance can never be wholly eliminated. Effective laboratory containment is, however, a realistic goal. Prevention of virus transmission through contaminated laboratory materials is addressed by WHO standards for biosafety. The principal challenge is to prevent transmission through unrecognized infectious laboratory workers. Such transmission is possible only if the following conditions occur: infectious and potentially infectious materials carrying wild poliovirus are present in the laboratory concerned; a laboratory operation exposes a worker to poliovirus; a worker is susceptible to an infection that results in the shedding of poliovirus; and the community is susceptible to poliovirus infections. At present it is difficult to envisage the elimination of any of these conditions. However, the risks of the first three can be greatly reduced so as to create a formidable barrier against poliovirus transmission to the community. Final biosafety recommendations must await post-eradication immunization policies adopted by the international community. PMID:12075368

Laboratory studies and Pompe disease: from suspicion to therapy monitoring

Directory of Open Access Journals (Sweden)

K. V. Savost’yanov

2016-01-01

Full Text Available Pompe disease (PD is a rare, progressive, commonly fatal inherited autosomal recessive disease that is difficult to diagnose due to its obvious clinical heterogeneity and low awareness among physicians. Access to the laboratory diagnosis of rare diseases increases every year. In the past several years, Russian and foreign laboratories have achieved considerable success in accelerating and improving the diagnostic accuracy of PD. Unfortunately, the Russian-language literature contains scarce relevant information on the laboratory diagnosis of PD. This review is to fill up this gap. 

Study of electron and neutrino interactions. Final report

International Nuclear Information System (INIS)

Abashian, A.

1997-01-01

This is the final report for the DOE-sponsored experimental particle physics program at Virginia Tech to study the properties of the Standard Model of strong and electroweak interactions. This contract (DE-AS05-80ER10713) covers the period from August 1, 1980 to January 31, 1993. Task B of this contract, headed by Professor Alexander Abashian, is described in this final report. This program has been pursued on many fronts by the researchers in a search for axions at SLAC, in electron-positron collisions in the AMY experiment at the TRISTAN collider in Japan, in measurements of muon decay properties in the MEGA and RHO experiments at the LAMPF accelerator, in a detailed analysis of scattering effects in the purported observation of a 17 keV neutrino at Oxford, in a search for a disoriented chiral condensate with the MiniMax experiment at Fermilab, and in an R ampersand D program on resistive plate counters that could find use in low-cost high-quality charged particle detection at low rates

Applications of industrial computed tomography at Los Alamos Scientific Laboratory

International Nuclear Information System (INIS)

Kruger, R.P.; Morris, R.A.; Wecksung, G.W.

1980-01-01

A research and development program was begun three years ago at the Los Alamos Scientific Laboratory (LASL) to study nonmedical applications of computed tomography. This program had several goals. The first goal was to develop the necessary reconstruction algorithms to accurately reconstruct cross sections of nonmedical industrial objects. The second goal was to be able to perform extensive tomographic simulations to determine the efficacy of tomographic reconstruction with a variety of hardware configurations. The final goal was to construct an inexpensive industrial prototype scanner with a high degree of design flexibility. The implementation of these program goals is described

Implementation of Scientific Community Laboratories and Their Effect on Student Conceptual Learning, Attitudes, and Understanding of Uncertainty

Science.gov (United States)

Lark, Adam

Scientific Community Laboratories, developed by The University of Maryland, have shown initial promise as laboratories meant to emulate the practice of doing physics. These laboratories have been re-created by incorporating their design elements with the University of Toledo course structure and resources. The laboratories have been titled the Scientific Learning Community (SLC) Laboratories. A comparative study between these SLC laboratories and the University of Toledo physics department's traditional laboratories was executed during the fall 2012 semester on first semester calculus-based physics students. Three tests were executed as pre-test and post-tests to capture the change in students' concept knowledge, attitudes, and understanding of uncertainty. The Force Concept Inventory (FCI) was used to evaluate students' conceptual changes through the semester and average normalized gains were compared between both traditional and SLC laboratories. The Colorado Learning Attitudes about Science Survey for Experimental Physics (E-CLASS) was conducted to elucidate students' change in attitudes through the course of each laboratory. Finally, interviews regarding data analysis and uncertainty were transcribed and coded to track changes in the way students understand uncertainty and data analysis in experimental physics after their participation in both laboratory type. Students in the SLC laboratories showed a notable an increase conceptual knowledge and attitudes when compared to traditional laboratories. SLC students' understanding of uncertainty showed most improvement, diverging completely from students in the traditional laboratories, who declined throughout the semester.

Pre-Service Chemistry Teachers' Competencies in the Laboratory: A Cross-Grade Study in Solution Preparation

Science.gov (United States)

Karatas, F. O.

2016-01-01

One of the prerequisites for chemistry teacher candidates is to demonstrate certain laboratory skills. This article aims to determine and discuss the competencies of pre-service chemistry teachers in a chemistry laboratory context working with solution chemistry content. The participants in this study consisted of a group of pre-service chemistry…

Calgary Laboratory Services

Directory of Open Access Journals (Sweden)

James R. Wright MD, PhD

2015-12-01

Full Text Available Calgary Laboratory Services provides global hospital and community laboratory services for Calgary and surrounding areas (population 1.4 million and global academic support for the University of Calgary Cumming School of Medicine. It developed rapidly after the Alberta Provincial Government implemented an austerity program to address rising health care costs and to address Alberta’s debt and deficit in 1994. Over roughly the next year, all hospital and community laboratory test funding within the province was put into a single budget, fee codes for fee-for-service test billing were closed, roughly 40% of the provincial laboratory budget was cut, and roughly 40% of the pathologists left the province of Alberta. In Calgary, in the face of these abrupt changes in the laboratory environment, private laboratories, publicly funded hospital laboratories and the medical school department precipitously and reluctantly merged in 1996. The origin of Calgary Laboratory Services was likened to an “unhappy shotgun marriage” by all parties. Although such a structure could save money by eliminating duplicated services and excess capacity and could provide excellent city-wide clinical service by increasing standardization, it was less clear whether it could provide strong academic support for a medical school. Over the past decade, iterations of the Calgary Laboratory Services model have been implemented or are being considered in other Canadian jurisdictions. This case study analyzes the evolution of Calgary Laboratory Services, provides a metric-based review of academic performance over time, and demonstrates that this model, essentially arising as an unplanned experiment, has merit within a Canadian health care context.

Hybrid Online Labs: Making Remote Laboratories Usable Under Unfavorable Bandwidth Conditions

Directory of Open Access Journals (Sweden)

Kayode Peter Ayodele

2012-11-01

Full Text Available One of few limitations of remote laboratory technology is the fact that access and usability of such laboratories depend largely on the existence of favorable bandwidth conditions between the remote user and the system under test. This dependence is regrettable because some of the institutions likely to find remote laboratories attractive are also those most likely to have severe bandwidth limitations. Also, a typical remote laboratory will be completely unusable to remote students in the event of an outright network downtime. In this paper, we propose a hybrid online laboratory architecture that allows the automatic generation of accurate software models of remote laboratories. Such models can be hosted closer to the student and during periods of unfavorable bandwidth conditions, students can successfully interact with such models in lieu of the real hardware. We identify the challenges that need to be resolved for such a scheme to be useful and discuss the process by which suitable modeling bases were chosen. Finally we present and discuss data from a first test of the system and conclude that such a scheme holds considerable promise in changing the way remote laboratories are used and viewed.

Knowledge and practices of pharmaceutical laboratory workers on laboratory safety

Directory of Open Access Journals (Sweden)

Esra Emerce

2017-09-01

Full Text Available Laboratories are classified as very hazardous workplaces. Objective: The aim of this descriptive study was to determine the knowledge and practice of laboratory safety by analysts and technicians in the laboratories of the Turkish Medicine and Medical Devices Agency. Methods:  85.0% (n=93 of the workers (n=109 was reached. A pre-tested, laboratory safety oriented, self-administered questionnaire was completed under observation. Results: Participants were mostly female (66,7%, had 12.8±8.2 years of laboratory experience and worked 24.6±10.3 hours per week. 53.8% of the employees generally worked with flammable and explosive substances, 29.0% with acute toxic or carcinogenic chemicals and 30.1% with physical dangers. Of all surveyed, 14.0% had never received formal training on laboratory safety. The proportion of ‘always use’ of laboratory coats, gloves, and goggles were 84.9%, 66.7%, and 6.5% respectively. 11.9% of the participants had at least one serious injury throughout their working lives and 24.7% had at least one small injury within the last 6 months. Among these injuries, incisions, bites and tears requiring no stiches (21.0% and the inhalation of chemical vapors (16.1% took first place. The mean value for the number of correct responses to questions on basic safety knowledge was 65.4±26.5, out of a possible 100. Conclusion: Overall, the participants have failed in some safety practices and have been eager to get regular education on laboratory safety.  From this point onwards, it would be appropriate for the employers to organize periodic trainings on laboratory safety.Keywords: Health personnel, laboratory personnel, occupational health, occupational safety, pharmacy

Presentation of the Nuclear Material Metrology Laboratory (LAMMAN)

International Nuclear Information System (INIS)

Arpigny, S.; Biscarrat, C.; Ruas, A.; Viallesoubranne, C.; Hanssens, A.; Roche, C.

2008-01-01

The EQRAIN Uranium or Plutonium programmes (Evaluation of the Quality of Analysis Results in the Nuclear Industry) have led to the creation of round-robins, which require reference solutions of uranyl nitrate or of plutonium nitrate to be made available. The samples are fabricated and packaged, and their benchmark values determined, by the Nuclear Material Metrology Laboratory in the Atalante facility. All the operations are carried out by highly precise weighing, including correction for air buoyancy. In order to guarantee the preservation of reference samples, a laser-sealing apparatus is used to condition the final solutions in ampoules. Random tests to check the concentration of uranium or plutonium are carried out on a certain number of ampoules after the sealing step. The analysis are performed on a photo-gravimetric analysis line (in glove box for Pu) based on the titanium potentiometric analysis method. The ampoules are then packaged and delivered to the participating laboratories. The French nuclear laboratories participating in the EQRAIN programs belong to the Cea and to the AREVA Group, with activities covering the entire fuel cycle. They have been joined by new participants from European, Japanese and South American laboratories

Presentation of the Nuclear Material Metrology Laboratory (LAMMAN)

Energy Technology Data Exchange (ETDEWEB)

Arpigny, S.; Biscarrat, C.; Ruas, A.; Viallesoubranne, C. [CEA/DEN/DRCP/SE2A/LAMM, Marcoule, BP 17171, 30207 Bagnols sur Ceze (France); Hanssens, A.; Roche, C. [CEA/DEN/DRCP/CETAMA Marcoule, BP 17171, 30207 Bagnols sur Ceze (France)

2008-07-01

The EQRAIN Uranium or Plutonium programmes (Evaluation of the Quality of Analysis Results in the Nuclear Industry) have led to the creation of round-robins, which require reference solutions of uranyl nitrate or of plutonium nitrate to be made available. The samples are fabricated and packaged, and their benchmark values determined, by the Nuclear Material Metrology Laboratory in the Atalante facility. All the operations are carried out by highly precise weighing, including correction for air buoyancy. In order to guarantee the preservation of reference samples, a laser-sealing apparatus is used to condition the final solutions in ampoules. Random tests to check the concentration of uranium or plutonium are carried out on a certain number of ampoules after the sealing step. The analysis are performed on a photo-gravimetric analysis line (in glove box for Pu) based on the titanium potentiometric analysis method. The ampoules are then packaged and delivered to the participating laboratories. The French nuclear laboratories participating in the EQRAIN programs belong to the Cea and to the AREVA Group, with activities covering the entire fuel cycle. They have been joined by new participants from European, Japanese and South American laboratories.

Feasibility study of medical isotope production at Sandia National Laboratories

International Nuclear Information System (INIS)

Massey, C.D.; Miller, D.L.; Carson, S.D.

1995-12-01

In late 1994, Sandia National Laboratories in Albuquerque, New Mexico, (SNL/NM), was instructed by the Department of Energy (DOE) Isotope Production and Distribution Program (IPDP) to examine the feasibility of producing medically useful radioisotopes using the Annular Core Research Reactor (ACRR) and the Hot Cell Facility (HCF). Los Alamos National Laboratory (LANL) would be expected to supply the targets to be irradiated in the ACRR. The intent of DOE would be to provide a capability to satisfy the North American health care system demand for 99 Mo, the parent of 99m Tc, in the event of an interruption in the current Canadian supply. 99m Tc is used in 70 to 80% of all nuclear medicine procedures in the US. The goal of the SNL/NM study effort is to determine the physical plant capability, infrastructure, and staffing necessary to meet the North American need for 99 Mo and to identify and examine all issues with potential for environmental impact

AISI Direct Steelmaking Program. Final technical report

Energy Technology Data Exchange (ETDEWEB)

Aukrust, E.

1994-08-01

This final report deals with the results of a 5-yr project for developing a more energy-efficient, environmentally friendly, less costly process for producing hot metal than current coke ovens and blast furnaces. In the process, iron ore pellets are smelted in a foamy slag created by reaction of coal char with molten slag to produce CO. The CO further reacts with oxygen, which also reacts with coal volatile matter, to produce the heat necessary to sustain the endothermic reduction reaction. The uncombusted CO and H{sub 2} from the coal are used to preheat and prereduce hematite pellets for the most efficient use of the energy in the coal. Laboratory programs confirmed that the process steps worked. Pilot plant studies were successful. Economic analysis for a 1 million tpy plant is promising.

Sister chromatid exchange analysis and chromosoma aberration studies in interventional cardiology laboratory workers. One year follow up study

International Nuclear Information System (INIS)

Erol, M.K.; Oztas, S.; Bozkurt, E.; Karakelleoglu, S.

2002-01-01

Invasive cardiology laboratory workers are occupationally exposed to chronic ionizing radiation. It is known that ionizing radiation has a damaging effect on chromosomes. In present study, we investigated the frequency of sister chromatid exchange (SCE) and chromosomal aberrations in 11 invasive cardiology laboratory workers and 11 healthy controls. After a vacation period, we took blood samples for chromosome analysis in months 0, 4, 8 and 12 (last two month period was the nonradiation time). The SCE frequencies did not change significantly after exposure to ionizing radiation in any worker. Our study has revealed that non-specific structural chromosome aberrations such as gaps, isogaps, acentric chromosomes, chromatids and chromosome breakage could be in the 4th and 8th months after ionizing radiation exposure in the metaphase plaques. All abnormal chromosomal effects had disappeared by the end of the two month non-exposure period in each worker. In conclusion, the results suggest that SCE frequencies are not significantly affected in invasive cardiology laboratory workers who are exposed occupationally to ionizing radiation, although some degree of reversible chromosomal aberrations did appear. (author)

Laboratory and field studies on an Indian strain of the brine shrimp Artemia

Digital Repository Service at National Institute of Oceanography (India)

Royan, J.P.

The Tuticorin strain of the brine shrimp @iArtemia@@ was studied under both laboratory and field conditions. Studies on the survival of the nauplii at different temperatures and salinities revealed that the nauplii preferred a salinity of 35 ppt...

[Knowledge management system for laboratory work and clinical decision support].

Science.gov (United States)

Inada, Masanori; Sato, Mayumi; Yoneyama, Akiko

2011-05-01

This paper discusses a knowledge management system for clinical laboratories. In the clinical laboratory of Toranomon Hospital, we receive about 20 questions relevant to laboratory tests per day from medical doctors or co-medical staff. These questions mostly involve the essence to appropriately accomplish laboratory tests. We have to answer them carefully and suitably because an incorrect answer may cause a medical accident. Up to now, no method has been in place to achieve a rapid response and standardized answers. For this reason, the laboratory staff have responded to various questions based on their individual knowledge. We began to develop a knowledge management system to promote the knowledge of staff working for the laboratory. This system is a type of knowledge base for assisting the work, such as inquiry management, laboratory consultation, process management, and clinical support. It consists of several functions: guiding laboratory test information, managing inquiries from medical staff, reporting results of patient consultation, distributing laboratory staffs notes, and recording guidelines for laboratory medicine. The laboratory test information guide has 2,000 records of medical test information registered in the database with flexible retrieval. The inquiry management tool provides a methos to record all questions, answer easily, and retrieve cases. It helps staff to respond appropriately in a short period of time. The consulting report system treats patients' claims regarding medical tests. The laboratory staffs notes enter a file management system so they can be accessed to aid in clinical support. Knowledge sharing using this function can achieve the transition from individual to organizational learning. Storing guidelines for laboratory medicine will support EBM. Finally, it is expected that this system will support intellectual activity concerning laboratory work and contribute to the practice of knowledge management for clinical work support.

Laboratories for the 21st Century: Case Studies, Molecular Foundry, Berkeley, California

Energy Technology Data Exchange (ETDEWEB)

2010-11-01

This case study provides information on the Molecular Foundry, which incorporates Labs21 principles in its design and construction. The design includes many of the strategies researched at Lawrence Berkeley Laboratory for energy efficient cleanroom and data centers.

1. Introduction. 2. Laboratory experiments. 3. Field experiments. 4. Integrated field-laboratory experiments. 5. Panel recommendations

International Nuclear Information System (INIS)

Anon.

1975-01-01

Some recommendations for the design of laboratory and field studies in marine radioecology are formulated. The difficulties concerning the comparability of various experimental methods used to measure the fluxes of radionuclides through marine organisms and ecosystems, and also the use of laboratory results to make predictions for the natural environment are discussed. Three working groups were established during the panel meeting, to consider laboratory experiments, field studies, and the design and execution of integrated laboratory and field studies respectively. A number of supporting papers dealing with marine radioecological experiments were presented

Service Quality and Patient Satisfaction: An Exploratory Study of Pathology Laboratories in Jaipur.

Science.gov (United States)

Agarwal, Anuradha; Singh, Maithili R P

2016-01-01

One of the most important parts of healthcare system is diagnostics. Nowadays, Indians have become more aware of their health, due to improved and better availability of health related information, increase in medical tourism, and expanding health insurance. The demand for better diagnostic facilities have increased with the increase in lifestyle related diseases, excesses use of chemicals in agriculture practices and change in food habits. It is expected that the Indian diagnostic market will grow from USD $5 billion in the year 2012 to USD $32 billion by the year 2020 with 20% CAGR (India Brand Equity Foundation 2015 ). Today patients have easy access of information regarding the health services and they have become more concerned about it as they look forward to receiving the maximum value for their money. To win the confidence of the patients and to maintain that trust, it is required to deliver the right services to the right person at the right time. The purpose of this study was to develop a scale to measure the service quality at pathology laboratory. A thorough review of literature revealed that there are studies related to healthcare service quality but there is no such established scale to measure service quality of pathology laboratory. Thus, the authors strived to develop a reliable and valid instrument to measure the patients' perception toward pathology laboratory service quality. For this exploratory study was conducted on the sample of 80 patients of the laboratories in Jaipur city. The reliability and factor structures were tested to purify the scale. The findings revealed 13 items, comprising of three dimensions of service quality: responsiveness, tangibility, and reliability.

Change Agent Strategies: A Study of the Michigan-Ohio Regional Educational Laboratory.

Science.gov (United States)

Miller, Peggy Lynne

This dissertation reports on a study of the planning and development activities of the Michigan-Ohio Regional Educational Laboratory (MOREL). The study attempted to assess (1) whether MOREL has accepted a change agent role, and (2) whether it has taken action that indicates recognition of what is known through the literature and research about…

Personnel-dosimetry intercomparison studies at the Oak Ridge National Laboratory

International Nuclear Information System (INIS)

Swaja, R.E.; Sims, C.S.

1982-01-01

Since 1974, seven annual personnel dosimetry intercomparison studies have been conducted at the Oak Ridge National Laboratory using the Health Physics Reactor. These studies have produced more than 2000 measurements by 72 participating organizations of neutron and gamma dose equivalents between 0.1 to 15.0 mSv in six mixed radiation fields. The relative performance of three basic types of personnel neutron dosimeters (nuclear emulsion film, thermoluminescent, and track-etch) and two basic types of gamma dosimeters (film and thermoluminescent) was assessed based on experimental results obtained during the seven intercomparisons

Impact of Laboratory Cross-Contamination on Molecular Epidemiology Studies of Tuberculosis

Science.gov (United States)

Martínez, Miguel; de Viedma, Darío García; Alonso, María; Andrés, Sandra; Bouza, Emilio; Cabezas, Teresa; Cabeza, Isabel; Reyes, Armando; Sánchez-Yebra, Waldo; Rodríguez, Manuel; Sánchez, M. Isabel; Rogado, M. Cruz; Fernández, Rosa; Peñafiel, Teresa; Martínez, Juan; Barroso, Pilar; Lucerna, M. Ángeles; Diez, L. Felipe; Gutiérrez, Carmelo

2006-01-01

Laboratory cross-contamination by Mycobacterium tuberculosis is known to be responsible for the misdiagnosis of tuberculosis, but its impact on other contexts has not been analyzed. We present the findings of a molecular epidemiology analysis in which the recent transmission events identified by a genotyping reference center were overestimated as a result of unnoticed laboratory cross-contamination in the original diagnostic laboratories. PMID:16891518

Thin film silicon solar cells: advanced processing and characterization - Final report

Energy Technology Data Exchange (ETDEWEB)

Ballif, Ch.

2008-04-15

This final report elaborated for the Swiss Federal Office of Energy (SFOE) takes a look at the results of a project carried out at the photovoltaics laboratory at the University of Neuchatel in Switzerland. The project aimed to demonstrate the production of high-efficiency thin-film silicon devices on flexible substrates using low cost processes. New ways of improving processing and characterisation are examined. The process and manufacturing know-how necessary to provide support for industrial partners within the framework of further projects is discussed. The authors state that the efficiency of most devices was significantly improved, both on glass substrates and on flexible plastic foils. The process reproducibility was also improved and the interactions between the different layers in the device are now said to be better understood. The report presents the results obtained and discusses substrate materials, transparent conductors, defect analyses and new characterisation tools. Finally, the laboratory infrastructure is described.

Reliability on intra-laboratory and inter-laboratory data of hair mineral analysis comparing with blood analysis.

Science.gov (United States)

Namkoong, Sun; Hong, Seung Phil; Kim, Myung Hwa; Park, Byung Cheol

2013-02-01

Nowadays, although its clinical value remains controversial institutions utilize hair mineral analysis. Arguments about the reliability of hair mineral analysis persist, and there have been evaluations of commercial laboratories performing hair mineral analysis. The objective of this study was to assess the reliability of intra-laboratory and inter-laboratory data at three commercial laboratories conducting hair mineral analysis, compared to serum mineral analysis. Two divided hair samples taken from near the scalp were submitted for analysis at the same time, to all laboratories, from one healthy volunteer. Each laboratory sent a report consisting of quantitative results and their interpretation of health implications. Differences among intra-laboratory and interlaboratory data were analyzed using SPSS version 12.0 (SPSS Inc., USA). All the laboratories used identical methods for quantitative analysis, and they generated consistent numerical results according to Friedman analysis of variance. However, the normal reference ranges of each laboratory varied. As such, each laboratory interpreted the patient's health differently. On intra-laboratory data, Wilcoxon analysis suggested they generated relatively coherent data, but laboratory B could not in one element, so its reliability was doubtful. In comparison with the blood test, laboratory C generated identical results, but not laboratory A and B. Hair mineral analysis has its limitations, considering the reliability of inter and intra laboratory analysis comparing with blood analysis. As such, clinicians should be cautious when applying hair mineral analysis as an ancillary tool. Each laboratory included in this study requires continuous refinement from now on for inducing standardized normal reference levels.

[Regional pilot study to evaluate the laboratory turnaround time according to the client source].

Science.gov (United States)

Salinas, M; López-Garrigós, M; Yago, M; Ortuño, M; Díaz, J; Marcaida, G; Chinchilla, V; Carratala, A; Aguado, C; Rodríguez-Borja, E; Laíz, B; Guaita, M; Esteban, A; Lorente, M A; Uris, J

2011-01-01

To show turnaround time to client source in eight laboratories covering eight Health Areas (2,014,475 inhabitants) of the Valencian Community (Spain). Internal Laboratory Information System (LIS) registers (test register and verification date and time), and daily LIS registers were used to design the indicators, These indicators showed the percentage of key tests requested (full blood count and serum glucose and thyrotropin) that were validated on the same day the blood was taken (inpatients and Primary Care and/or at 12 a.m. (inpatients). Urgent (stat) tests were also registered as key tests (serum troponin and potassium) and were recorded in minutes. Registers were collected and indicators calculated automatically through a Data Warehouse application and OLAP cube software. Long turnaround time differences were observed at 12 a.m. in inpatients, and in the day of sample extraction in primary care patients. The variability in turnaround of stat tests is related to hospital size, activity and validation by the laboratory physician. The study results show the large turnaround time disparity in eight Health Care Areas of Valencian Community. The various requesting sources covered by the laboratories create the need for continuous mapping processes redesign and benchmarking studies to achieve customer satisfaction. Copyright © 2010 SECA. Published by Elsevier Espana. All rights reserved.

Study about the behaviour of fishways in laboratory. Experiments 2009-2010

International Nuclear Information System (INIS)

Lara Dominguez, A.; Aramburu Godinez, E.; Berges Acedo, J. A.; Morcillo Alonso, F.; Castillo Blanco, M.

2011-01-01

The Hydraulic Laboratory of the Center for Hydro graphic Studies (CEDEX) is carrying out a study about the behaviour of some salmonid and cryprinid fish species in a vertical slot fishways built in the Laboratory, in order to know the relationship between hydraulic and biological parameters and to obtain valid design criteria. Its the first time in our country that fish are been monitored in a fishways using a RFD system, underwater and cenital cameras. First at all, the hydraulic of this typology has been characterised. An experiment protocol has been established to optimize the results. Regarding fish movements in the fishways, on the one hand we have found that fish always rest ascending the pass and, on the other, an influence of the flow on the percentage of fish that ascend the whole pass. Moreover, a tool analyze the efficiency of a fish way model according to biological criteria has been contrasted but it needs to be calibrated with biological variables obtained from native fish species. concerning fish fatigue and effort, studies about physiological parameters in plasma (hematocrit, glucose, cortisol and lactate) have implemented and the results point out the need to increase the studies with physiological parameters in muscle. (Author) 14 refs.

Intercomparison Measurements Exercises of Mobile Radiological Laboratories (invited paper)

International Nuclear Information System (INIS)

Martincic, R.

2000-01-01

After the reactor accident in Chernobyl, the importance of mobile radiological laboratories became evident and in situ gamma spectrometry became a common method for the rapid detection of gamma emitters in the environment. Since then different institutions in European countries have organised periodic intercomparison exercises of mobile radiological laboratories to improve the measurement methods and the preparedness of emergency monitoring teams. The general objectives of these workshops are to promote the knowledge and to exchange the experiences of emergency monitoring teams that use mobile radiological laboratories, as well as to foster the international harmonisation of emergency monitoring procedures and cooperation among teams. Finally, the results of intercomparison measurements have shown that such exercises are mandatory for rapid, efficient and correct environmental monitoring in nuclear or radiological emergencies. An overview of these intercomparison measurements is given, results from the 1999 intercomparison workshop are presented and lessons learned are discussed. (author)

Safeguards Knowledge Management & Retention at U.S. National Laboratories.

Energy Technology Data Exchange (ETDEWEB)

Haddal, Risa [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jones, Rebecca [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Bersell, Bridget [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Frazar, Sarah [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Burbank, Roberta [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Stevens, Rebecca [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Cain, Ron [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Kirk, Bernadette [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Morell, Sean [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

2017-09-01

In 2017, four U.S. National Laboratories collaborated on behalf of DOE/NNSA to explore the safeguards knowledge retention problem, identify possible approaches, and develop a strategy to address it. The one-year effort consisted of four primary tasks. First, the project sought to identify critical safeguards information at risk of loss. Second, a survey and workshop were conducted to assess nine U.S. National Laboratories' efforts to determine current safeguards knowledge retention practices and challenges, and identify best practices. Third, specific tools were developed to identify and predict critical safeguards knowledge gaps and how best to recruit in order to fill those gaps. Finally, based on findings from the first three tasks and research on other organizational approaches to address similar issues, a strategy was developed on potential knowledge retention methods, customized HR policies, and best practices that could be implemented across the National Laboratory Complex.

Site Study Plan for laboratory soil mechanics, Deaf Smith County site, Texas: Revision 1

International Nuclear Information System (INIS)

1987-12-01

This Site Study Plan for laboratory soil mechanics describes the laboratory testing to be conducted on soil samples collected as part of the characterization of the Deaf Smith County site, Texas. This study provides for measurements of index, mechanical, thermal, hydrologic, chemical, and mineral properties of soils from boring throughout the site. Samples will be taken from Playa Borings/Trenching, Transportation/Utilities Foundation Borings, Repository Surface Facilities Design Foundation Borings, and Exploratory Shaft Facilities Design Foundation Borings. Data from the laboratory tests will be used for soil strata characterization, design of foundations for surface structures, design of transportation facilities and utility structures, design of impoundments, design of shaft lining, design of the shaft freeze wall, shaft permitting, performance assessment calculations, and other program requirements. A tentative testing schedule and milestone log are given. A quality assurance program will be utilized to assure that activities affecting quality are performed correctly and that appropriate documentation is maintained. 18 refs., 6 figs., 3 tabs

Laboratory Animal Workers' Attitudes and Perceptions Concerning Occupational Risk and Injury.

Science.gov (United States)

Steelman, Eric D; Alexander, Jeffrey L

2016-01-01

Little is known regarding the risk perceptions and attitudes of laboratory animal care workers toward biologic safety. The purpose of this descriptive study was to assess the attitudes and perceptions of laboratory animal workers toward occupational and injury risk. Subscribers to the CompMed and TechLink listservs (n = 4808) were surveyed electronically, and 5.3% responded; data from 215 respondents were included in the final analysis. Primary variables of interest included AALAS certifications status, level of education, and responses to Likert-scale questions related to attitudes and perceptions of occupational risk and injury. Nonparametric (χ(2)) testing and measures of central tendency and dispersion were used to analyze and describe the data. According to 88.6% of respondents, biologic safety training is provided with information about zoonotic diseases of laboratory animals. Level of education was significantly related to perception of importance regarding wearing personal protective equipment. Participants indicated that appropriate support from coworkers and management staff is received, especially when performance and perception are hindered due to stress and fatigue. Laboratory animal staff are susceptible to injury and exposure to dangerous organisms and toxic substances. For this reason, to maximize safety, yearly biologic safety training should be provided, the importance of protective equipment adherence strengthened, and the culture of safety made a priority within the institution.

Field and Laboratory Studies of Atmospheric Organic Aerosol

Science.gov (United States)

Coggon, Matthew Mitchell

This thesis is the culmination of field and laboratory studies aimed at assessing processes that affect the composition and distribution of atmospheric organic aerosol. An emphasis is placed on measurements conducted using compact and high-resolution Aerodyne Aerosol Mass Spectrometers (AMS). The first three chapters summarize results from aircraft campaigns designed to evaluate anthropogenic and biogenic impacts on marine aerosol and clouds off the coast of California. Subsequent chapters describe laboratory studies intended to evaluate gas and particle-phase mechanisms of organic aerosol oxidation. The 2013 Nucleation in California Experiment (NiCE) was a campaign designed to study environments impacted by nucleated and/or freshly formed aerosol particles. Terrestrial biogenic aerosol with > 85% organic mass was observed to reside in the free troposphere above marine stratocumulus. This biogenic organic aerosol (BOA) originated from the Northwestern United States and was transported to the marine atmosphere during periodic cloud-clearing events. Spectra recorded by a cloud condensation nuclei counter demonstrated that BOA is CCN active. BOA enhancements at latitudes north of San Francisco, CA coincided with enhanced cloud water concentrations of organic species such as acetate and formate. Airborne measurements conducted during the 2011 Eastern Pacific Emitted Aerosol Cloud Experiment (E-PEACE) were aimed at evaluating the contribution of ship emissions to the properties of marine aerosol and clouds off the coast of central California. In one study, analysis of organic aerosol mass spectra during periods of enhanced shipping activity yielded unique tracers indicative of cloud-processed ship emissions (m/z 42 and 99). The variation of their organic fraction (f42 and f 99) was found to coincide with periods of heavy (f 42 > 0.15; f99 > 0.04), moderate (0.05 controlled organic plume emitted from the R/V Point Sur. Under sunny conditions, nucleated particles composed

Design study of the underground facilities, the Mizunami Underground Research Laboratory

International Nuclear Information System (INIS)

Ishizuka, Mineo; Noda, Masaru; Shiogama, Yukihiro; Adachi, Tetsuya

1999-02-01

Geoscientific research on the deep geological environment has been performed by Japan Nuclear Cycle Development Institute (JNC). This research is supported by the 'Long-Term Program for Research, Development and Utilization of Nuclear Energy'. The Mizunami Underground Research Laboratory (MIU) is planned to be constructed at the Shobasama-bora site belonging to JNC. A wide range of geoscientific research and development activities which have been previously performed in and around the Tono mine is planned to be expanded in the laboratory. The MIU consisted of surface and underground facilities excavated to a depth of about 1,000 meters. In this design study, the overall layout and basic design of the underground facility and the composition of the overall research program, includes the construction of the underground facility are studied. Based on the concept of the underground facility which have been developed in 1998, the research activities which will be performed in the MIU are selected and the overall research program is revised in this year. The basic construction method and the construction equipment are also estimated. (author)

Design study of underground facility of the Mizunami Underground Research Laboratory

International Nuclear Information System (INIS)

Ishizuka, Mineo; Noda, Masaru; Shiogama, Yukihiro; Adachi, Tetsuya

1999-02-01

Geoscientific research on deep geological environment has been performed by Japan Nuclear Cycle Development Institute (JNC). This research is supported by the 'Long-Term Program for Research, Development and Utilization of Nuclear Energy'. The Mizunami Underground Research Laboratory (MIU) is planned to be constructed at Shobasama-bora site belonging to JNC. A wide range of geoscientific research and development activities which have been previously performed in and around the Tono mine is planned to be expanded in the laboratory. The MIU is consisted of surface and underground facilities down to the depth of about 1,000 meters. In this design study, the overall layout and basic design of the underground facility and the composition of the overall research program which includes the construction of the underground facility are studied. Based on the concept of the underground facility which have been developed last year, the research activities which will be performed in the MIU are selected and the overall research program is revised in this year. The basic construction method and the construction equipment are also estimated. (author)

25th-year jubilee edition of the Hot Laboratory's annual report

International Nuclear Information System (INIS)

Bart, G.

1989-07-01

The topics discussed in this report concern the history of PSI's Hot Laboratory, nuclear fuel development performed there during the last twenty years, post irradiation examination work, basic research for a final repository of radioactive wastes, and neutron embrittlement experiments. 44 figs., 1 tab., 82 refs

Investigating Student Perceptions of the Chemistry Laboratory and Their Approaches to Learning in the Laboratory

Science.gov (United States)

Berger, Spencer Granett

This dissertation explores student perceptions of the instructional chemistry laboratory and the approaches students take when learning in the laboratory environment. To measure student perceptions of the chemistry laboratory, a survey instrument was developed. 413 students responded to the survey during the Fall 2011 semester. Students' perception of the usefulness of the laboratory in helping them learn chemistry in high school was related to several factors regarding their experiences in high school chemistry. Students' perception of the usefulness of the laboratory in helping them learn chemistry in college was also measured. Reasons students provided for the usefulness of the laboratory were categorized. To characterize approaches to learning in the laboratory, students were interviewed midway through semester (N=18). The interviews were used to create a framework describing learning approaches that students use in the laboratory environment. Students were categorized into three levels: students who view the laboratory as a requirement, students who believe that the laboratory augments their understanding, and students who view the laboratory as an important part of science. These categories describe the types of strategies students used when conducting experiments. To further explore the relationship between students' perception of the laboratory and their approaches to learning, two case studies are described. These case studies involve interviews in the beginning and end of the semester. In the interviews, students reflect on what they have learned in the laboratory and describe their perceptions of the laboratory environment. In order to encourage students to adopt higher-level approaches to learning in the laboratory, a metacognitive intervention was created. The intervention involved supplementary questions that students would answer while completing laboratory experiments. The questions were designed to encourage students to think critically about the

Service quality framework for clinical laboratories.

Science.gov (United States)

Ramessur, Vinaysing; Hurreeram, Dinesh Kumar; Maistry, Kaylasson

2015-01-01

The purpose of this paper is to illustrate a service quality framework that enhances service delivery in clinical laboratories by gauging medical practitioner satisfaction and by providing avenues for continuous improvement. The case study method has been used for conducting the exploratory study, with focus on the Mauritian public clinical laboratory. A structured questionnaire based on the SERVQUAL service quality model was used for data collection, analysis and for the development of the service quality framework. The study confirms the pertinence of the following service quality dimensions within the context of clinical laboratories: tangibility, reliability, responsiveness, turnaround time, technology, test reports, communication and laboratory staff attitude and behaviour. The service quality framework developed, termed LabSERV, is vital for clinical laboratories in the search for improving service delivery to medical practitioners. This is a pioneering work carried out in the clinical laboratory sector in Mauritius. Medical practitioner expectations and perceptions have been simultaneously considered to generate a novel service quality framework for clinical laboratories.

HFC-134A and HCFC-22 supermarket refrigeration demonstration and laboratory testing. Phase I. Final report

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-04-01

Aspen Systems and a team of nineteen agencies and industry participants conducted a series of tests to determine the performance of HFC-134a, HCFC-22, and CFC-502 for supermarket application. This effort constitutes the first phase of a larger project aimed at carrying out both laboratory and demonstration tests of the most viable HFC refrigerants and the refrigerants they replace. The results of the Phase I effort are presented in the present report. The second phase of the project has also been completed. It centered on testing all viable HFC replacement refrigerants for CFC-502. These were HFC-507, HFC-404A, and HFC-407A. The latter results are published in the Phase II report for this project. As part of Phase I, a refrigeration rack utilizing a horizontal open drive screw compressor was constructed in our laboratory. This refrigeration rack is a duplicate of one we have installed in a supermarket in Clifton Park, NY.

Brain Implants for Prediction and Mitigation of Epileptic Seizures - Final CRADA Report

Energy Technology Data Exchange (ETDEWEB)

Gopalsami, Nachappa

2016-09-29

This is a CRADA final report on C0100901 between Argonne National Laboratory and Flint Hills Scientific, LLC of Lawrence, Kansas. Two brain implantable probes, a surface acoustic wave probe and a miniature cooling probe, were designed, built, and tested with excellent results.

Analytical laboratory and mobile sampling platform

International Nuclear Information System (INIS)

Stetzenbach, K.; Smiecinski, A.

1996-01-01

This is the final report for the Analytical Laboratory and Mobile Sampling Platform project. This report contains only major findings and conclusions resulting from this project. Detailed reports of all activities performed for this project were provided to the Project Office every quarter since the beginning of the project. This report contains water chemistry data for samples collected in the Nevada section of Death Valley National Park (Triangle Area Springs), Nevada Test Site springs, Pahranagat Valley springs, Nevada Test Site wells, Spring Mountain springs and Crater Flat and Amargosa Valley wells

Aespoe Hard Rock Laboratory. Annual Report 2002

Energy Technology Data Exchange (ETDEWEB)

NONE

2006-06-15

The Aespoe Hard Rock Laboratory (HRL), in the Simpevarp area in the municipality of Oskarshamn constitutes an important part of SKB's work with the design and construction of a deep geological repository for final disposal of spent nuclear fuel. One of the fundamental reasons behind SKB's decision to construct an underground laboratory was to create an opportunity for research, development and demonstration in a realistic and undisturbed rock environment down to repository depth. The underground part of the laboratory consists of a tunnel from the Simpevarp peninsula to the southern part of Aespoe where the tunnel continues in a spiral down to a depth of 460 m. Aespoe HRL has been in operation since 1995 and considerable international interest has been shown in its associated research, as well as in the development and demonstration tasks. Most of the research is focused on processes of importance for the long-term safety of a final repository for spent nuclear fuel. Demonstration addresses the performance of the engineered barriers and practical means of constructing and operating a repository for spent fuel. To meet the overall time schedule for SKB's RD and D work, the following stage goals were initially defined for the work at the Aespoe HRL: 1. Verify pre-investigation methods. Demonstrate that investigations on the ground surface and in boreholes provide sufficient data on essential safety-related properties of the rock at repository level. 2. Finalise detailed investigation methodology. Refine and verify the methods and the technology needed for characterisation of the rock in the detailed site investigations. 3. Test models for description of the barrier functions at natural conditions. Further develop, and at repository depth, test methods and models for description of groundwater flow, radionuclide migration and chemical conditions during operation of a repository and after closure. 4. Demonstrate technology for and function of important

Aespoe Hard Rock Laboratory. Annual Report 2005

International Nuclear Information System (INIS)

2006-06-01

The Aespoe Hard Rock Laboratory (HRL), in the Simpevarp area in the municipality of Oskarshamn constitutes an important part of SKB's work with the design and construction of a deep geological repository for final disposal of spent nuclear fuel. One of the fundamental reasons behind SKB's decision to construct an underground laboratory was to create an opportunity for research, development and demonstration in a realistic and undisturbed rock environment down to repository depth. The underground part of the laboratory consists of a tunnel from the Simpevarp peninsula to the southern part of Aespoe where the tunnel continues in a spiral down to a depth of 460 m. Aespoe HRL has been in operation since 1995 and considerable international interest has been shown in its associated research, as well as in the development and demonstration tasks. Most of the research is focused on processes of importance for the long-term safety of a final repository for spent nuclear fuel. Demonstration addresses the performance of the engineered barriers and practical means of constructing and operating a repository for spent fuel. To meet the overall time schedule for SKB's RD and D work, the following stage goals were initially defined for the work at the Aespoe HRL: 1. Verify pre-investigation methods. Demonstrate that investigations on the ground surface and in boreholes provide sufficient data on essential safety-related properties of the rock at repository level. 2. Finalise detailed investigation methodology. Refine and verify the methods and the technology needed for characterisation of the rock in the detailed site investigations. 3. Test models for description of the barrier functions at natural conditions. Further develop, and at repository depth, test methods and models for description of groundwater flow, radionuclide migration and chemical conditions during operation of a repository and after closure. 4. Demonstrate technology for and function of important parts of the

Recovery of uranium from sea water - a laboratory study

International Nuclear Information System (INIS)

Jayawant, D.V.; Iyer, N.S.; Koppiker, K.S.

1991-01-01

Sea water contains traces of uranium, but the volume of sea water being enormous, the total quantity of uranium available from the sources is very large. From time to time, claims have been made elsewhere that a breakthrough has been made in developing a technology to recovery this uranium at an economic cost. Studies have been carried out at Uranium Extraction Division over a few years to develop a suitable technique to separate the uranium from sea water. Studies were primarily directed towards preparation of suitable inorganic ion exchangers and studying their properties. In this paper preparation of ion exchangers based on hydrous titanium oxide and the data collected in laboratory trials on their application for uranium adsorption from sea water are presented. (author). 11 refs., 2 tabs

Degradation of herbicides in shallow Danish aquifers - an integrated laboratory and field study

DEFF Research Database (Denmark)

Albrechtsen, Hans-Jørgen; Mills, M.; Aamand, J.

2001-01-01

Degradation of pesticides in aquifers has been evaluated based on a number of co-ordinated field and laboratory studies carried out in Danish aquifers. These studies included investigations of vertical and horizontal variability in degradation rates from the vadose zone to an aquifer, the effects...

Commercialization of a DOE Laboratory

International Nuclear Information System (INIS)

Stephenson, Barry A.

2008-01-01

capabilities as a niche market play to success. The niche was further defined by preservation of the ability to handle samples contaminated with radiological materials and those with classification concerns. These decisions enabled early marketing plans to be built on existing clientele and provided an identifiable group to which future marketing could be expanded. Finally, recruitment of key players with commercial laboratory experience proved to be a key factor for success. This experience base was valuable in avoiding early mistakes in the laboratory startup phase and provided some connection to a commercial client base. As the business has grown, professionals with commercial laboratory experience have been recruited and offered ownership in the business as an incentive for joining the group. If the process were to be repeated, early involvement of an individual with commercial sales experience would be helpful in broadening the base of commercial clients. An increased emphasis on research funding such as funding received from Small Business Innovative Research (SBIR) sources would be used to form a portion of the economic base for the business. More partnerships with businesses whose services compliment those of the laboratory would expand available client base. More flexible staffing arrangements would be negotiated early on as a cost-control measure. In conclusion, the re-industrialization concept can be successful. Candidates for re-industrialization must be chosen by matching services to be offered to market needs. Implementation is best accomplished by entrepreneurs who personally profit from a successful operation of the business

Life sciences: Lawrence Berkeley Laboratory, 1988

International Nuclear Information System (INIS)

1989-07-01

Life Sciences Research at LBL has both a long history and a new visibility. The physics technologies pioneered in the days of Ernest O. Lawrence found almost immediate application in the medical research conducted by Ernest's brother, John Lawrence. And the tradition of nuclear medicine continues today, largely uninterrupted for more than 50 years. Until recently, though, life sciences research has been a secondary force at the Lawrence Berkeley Laboratory (LBL). Today, a true multi-program laboratory has emerged, in which the life sciences participate as a full partner. The LBL Human Genome Center is a contribution to the growing international effort to map the human genome. Its achievements represent LBL divisions, including Engineering, Materials and Chemical Sciences, and Information and Computing Sciences, along with Cell and Molecular Biology and Chemical Biodynamics. The Advanced Light Source Life Sciences Center will comprise not only beamlines and experimental end stations, but also supporting laboratories and office space for scientists from across the US. This effort reflects a confluence of scientific disciplines --- this time represented by individuals from the life sciences divisions and by engineers and physicists associated with the Advanced Light Source project. And finally, this report itself, the first summarizing the efforts of all four life sciences divisions, suggests a new spirit of cooperation. 30 figs

Cassini's Grand Finale Overview

Science.gov (United States)

Spilker, L. J.

2017-12-01

Finale orbits will be discussed. The research described in this paper was carried out in part at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with the National Aeronautics and Space Administration. Copyright 2017 California Institute of Technology. Government sponsorship is acknowledged.

Addressing the key communication barriers between microbiology laboratories and clinical units: a qualitative study.

Science.gov (United States)

Skodvin, Brita; Aase, Karina; Brekken, Anita Løvås; Charani, Esmita; Lindemann, Paul Christoffer; Smith, Ingrid

2017-09-01

Many countries are on the brink of establishing antibiotic stewardship programmes in hospitals nationwide. In a previous study we found that communication between microbiology laboratories and clinical units is a barrier to implementing efficient antibiotic stewardship programmes in Norway. We have now addressed the key communication barriers between microbiology laboratories and clinical units from a laboratory point of view. Qualitative semi-structured interviews were conducted with 18 employees (managers, doctors and technicians) from six diverse Norwegian microbiological laboratories, representing all four regional health authorities. Interviews were recorded and transcribed verbatim. Thematic analysis was applied, identifying emergent themes, subthemes and corresponding descriptions. The main barrier to communication is disruption involving specimen logistics, information on request forms, verbal reporting of test results and information transfer between poorly integrated IT systems. Furthermore, communication is challenged by lack of insight into each other's area of expertise and limited provision of laboratory services, leading to prolonged turnaround time, limited advisory services and restricted opening hours. Communication between microbiology laboratories and clinical units can be improved by a review of testing processes, educational programmes to increase insights into the other's area of expertise, an evaluation of work tasks and expansion of rapid and point-of-care test services. Antibiotic stewardship programmes may serve as a valuable framework to establish these measures. © The Author 2017. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy.

Efficiency in pathology laboratories: a survey of operations management in NHS bacteriology.

Science.gov (United States)

Szczepura, A K

1991-01-01

In recent years pathology laboratory services in the U.K. have experienced large increases in demand. But the extent to which U.K. laboratories have introduced controls to limit unnecessary procedures within the laboratory was previously unclear. This paper presents the results of a survey of all 343 NHS bacteriology laboratories which records the extent to which such operations management controls are now in place. The survey shows large differences between laboratories. Quality controls over inputs, the use of screening tests as a culture substitute, the use of direct susceptibility testing, controls over routine antibiotic susceptibility testing, and controls over reporting of results all vary widely. The survey also records the prevalence of hospital antibiotic policies, the extent to which laboratories produce antibiograms for user clinicians, the degree of computerisation in data handling, and the degree of automation in processing specimens. Finally, the survey uncovers a large variation between NHS labs in the percentage of bacteriology samples which prove positive and lead to antibiotic susceptibility tests being carried out.

Mixed Reality Environment for Web-Based Laboratory Interactive Learning

Directory of Open Access Journals (Sweden)

A. I. Saleem

2008-02-01

Full Text Available This paper presents a web-based laboratory fordistance learners by incorporating simulation andhardware implementation into web-based e-learningsystems. It presents a development consisting of laboratorycourse through internet based on mixed reality technique tosetup, run and manipulateset of experiments. Eachexperiment has been designed in a way that allows thelearner to manipulate the components and check if it worksproperly in order to achieve the experiment objective. Theproposed laboratory e-learning tool has web-basedcomponents accessed by authorized users. Learners canacquire the necessary skills they need, while learning thetheory of the experiment and the basic characteristics ofeach component used in the experiment. Finally, a casestudy was conducted to show the feasibility and efficiencyof the proposed method.

Privacy and security of patient data in the pathology laboratory.

Science.gov (United States)

Cucoranu, Ioan C; Parwani, Anil V; West, Andrew J; Romero-Lauro, Gonzalo; Nauman, Kevin; Carter, Alexis B; Balis, Ulysses J; Tuthill, Mark J; Pantanowitz, Liron

2013-01-01

Data protection and security are critical components of routine pathology practice because laboratories are legally required to securely store and transmit electronic patient data. With increasing connectivity of information systems, laboratory work-stations, and instruments themselves to the Internet, the demand to continuously protect and secure laboratory information can become a daunting task. This review addresses informatics security issues in the pathology laboratory related to passwords, biometric devices, data encryption, internet security, virtual private networks, firewalls, anti-viral software, and emergency security situations, as well as the potential impact that newer technologies such as mobile devices have on the privacy and security of electronic protected health information (ePHI). In the United States, the Health Insurance Portability and Accountability Act (HIPAA) govern the privacy and protection of medical information and health records. The HIPAA security standards final rule mandate administrative, physical, and technical safeguards to ensure the confidentiality, integrity, and security of ePHI. Importantly, security failures often lead to privacy breaches, invoking the HIPAA privacy rule as well. Therefore, this review also highlights key aspects of HIPAA and its impact on the pathology laboratory in the United States.

Privacy and security of patient data in the pathology laboratory

Directory of Open Access Journals (Sweden)

Ioan C Cucoranu

2013-01-01

Full Text Available Data protection and security are critical components of routine pathology practice because laboratories are legally required to securely store and transmit electronic patient data. With increasing connectivity of information systems, laboratory work-stations, and instruments themselves to the Internet, the demand to continuously protect and secure laboratory information can become a daunting task. This review addresses informatics security issues in the pathology laboratory related to passwords, biometric devices, data encryption, internet security, virtual private networks, firewalls, anti-viral software, and emergency security situations, as well as the potential impact that newer technologies such as mobile devices have on the privacy and security of electronic protected health information (ePHI. In the United States, the Health Insurance Portability and Accountability Act (HIPAA govern the privacy and protection of medical information and health records. The HIPAA security standards final rule mandate administrative, physical, and technical safeguards to ensure the confidentiality, integrity, and security of ePHI. Importantly, security failures often lead to privacy breaches, invoking the HIPAA privacy rule as well. Therefore, this review also highlights key aspects of HIPAA and its impact on the pathology laboratory in the United States.

Assessing Clinical Laboratory Quality: A College of American Pathologists Q-Probes Study of Prothrombin Time INR Structures, Processes, and Outcomes in 98 Laboratories.

Science.gov (United States)

Howanitz, Peter J; Darcy, Theresa P; Meier, Frederick A; Bashleben, Christine P

2015-09-01

The anticoagulant warfarin has been identified as the second most frequent drug responsible for serious, disabling, and fatal adverse drug events in the United States, and its effect on blood coagulation is monitored by the laboratory test called international normalized ratio (INR). To determine the presence of INR policies and procedures, INR practices, and completeness and timeliness of reporting critical INR results in participants' clinical laboratories. Participants reviewed their INR policies and procedure requirements, identified their practices by using a questionnaire, and studied completeness of documentation and timeliness of reporting critical value INR results for outpatients and emergency department patients. In 98 participating institutions, the 5 required policies and procedures were in place in 93% to 99% of clinical laboratories. Fifteen options for the allowable variations among duplicate results from different analyzers, 12 different timeliness goals for reporting critical values, and 18 unique critical value limits were used by participants. All required documentation elements were present in 94.8% of 192 reviewed INR validation reports. Critical value INR results were reported within the time frame established by the laboratory for 93.4% of 2604 results, but 1.0% of results were not reported. Although the median laboratories successfully communicated all critical results within their established time frames and had all the required validation elements based in their 2 most recent INR calculations, those participants at the lowest 10th percentile were successful in 80.0% and 85.7% of these requirements, respectively. Significant opportunities exist for adherence to INR procedural requirements and for practice patterns and timeliness goals for INR critical results' reporting.

Rethinking Laboratory Notebooks

DEFF Research Database (Denmark)

Klokmose, Clemens Nylandsted; Zander, Pär-Ola

2010-01-01

We take digitalization of laboratory work practice as a challenging design domain to explore. There are obvious drawbacks with the use of paper instead of ICT in the collaborative writing that takes place in laboratory notebooks; yet paper persist in being the most common solution. The ultimate aim...... with our study is to produce design relevant knowledge that can envisage an ICT solution that keeps as many advantages of paper as possible, but with the strength of electronic laboratory notebooks as well. Rather than assuming that users are technophobic and unable to appropriate state of the art software...

Exit competencies in pathology and laboratory medicine for graduating medical students: the Canadian approach.

Science.gov (United States)

Ford, Jason; Pambrun, Chantale

2015-05-01

Physicians in every medical and surgical field must be able to use pathology concepts and skills in their practice: for example, they must order and interpret the correct laboratory tests, they must use their understanding of pathogenesis to diagnose and treat, and they must work with the laboratory to care for their patients. These important concepts and skills may be ignored by medical schools and even national/international organizations setting graduation expectations for medical students. There is an evolving international consensus about the importance of exit competencies for medical school graduates, which define the measurable or observable behaviors each graduate must be able to demonstrate. The Canadian Association of Pathologists (CAP) Education Group set out to establish the basic competencies in pathology and laboratory medicine which should be expected of every medical graduate: not competencies for pathologists, but for medical graduates who intend to enter any residency program. We defined 4 targets for pathology and laboratory medicine exit competencies: that they represent only measurable behaviors, that they be clinically focused, that they be generalizable to every medical graduate, and that the final competency document be user-friendly. A set of competencies was developed iteratively and underwent final revision at the 2012 CAP annual meeting. These competencies were subsequently endorsed by the CAP executive and the Canadian Leadership Council on Laboratory Medicine. This clinically focused consensus document provides the first comprehensive list of exit competencies in pathology and laboratory medicine for undergraduate medical education. Copyright © 2015 Elsevier Inc. All rights reserved.

Fire vs. Metal: A Laboratory Study Demonstrating Microbial Responses to Soil Disturbances

Science.gov (United States)

Stromberger, Mary E.

2005-01-01

Incubation studies are traditionally used in soil microbiology laboratory classes to demonstrate microbial respiration and N mineralization-immobilization processes. Sometimes these exercises are done to calculate a N balance in N fertilizer-amended soils. However, examining microbial responses to environmental perturbations would appeal to soil…

Experimental Study of Drag Resistance using a Laboratory Scale Rotary Set-Up

DEFF Research Database (Denmark)

Erik Weinell, Claus; Olsen, Kenneth N.; Christoffersen, Martin W.

2003-01-01

This work covers an experimental study of the drag resistance of different painted surfaces and simulated large-scale irregularities, viz. dry spraying, weld seams, barnacle fouling and paint remains. A laboratory scale rotary set-up was used to determine the drag resistance, and the surface...

Round-Robin Studies on Roll-Processed ITO-free Organic Tandem Solar Cells Combined with Inter-Laboratory Stability Studies

DEFF Research Database (Denmark)

Livi, Francesco; Søndergaard, Roar R.; Andersen, Thomas Rieks

2015-01-01

Roll-processed, indium tin oxide (ITO)-free, flexible, organic tandem solar cells and modules have been realized and used in round-robin studies as well as in parallel inter-laboratory stability studies. The tandem cells/modules show no significant difference in comparison to their single...

How compliant are technicians with universal safety measures in medical laboratories in Croatia?--A pilot study.

Science.gov (United States)

Dukic, Kristina; Zoric, Matea; Pozaic, Petra; Starcic, Jelena; Culjak, Marija; Saracevic, Andrea; Miler, Marijana

2015-01-01

This pilot study aimed to investigate the use of personal protective equipment (PPE) and compliance to the code of conduct (rules defined in institutional, governmental and professional guidelines) among laboratory technicians in Croatian medical laboratories. In addition, we explored the differences in compliance between participants of different age groups, laboratory ownership and accreditation status. An anonymous and voluntary survey with 15 questions was conducted among Croatian medical laboratory technicians (N=217). The questions were divided into two groups: demographic characteristics and the use of PPE. The questions of the second part were graded according to the Likert scale (1-4) and an overall score, shown as median and range (min-max), was calculated for each participant. Differences between the overall scores were tested for each group of participants. The majority of participants always wear protective clothes at work, 38.7% of them always wear gloves in daily routine, more than 30.0% consume food and almost half of them drink beverages at workplace. A significantly lower overall score was found for participants working in public compared to private laboratories (36 (16-40) vs. 40 (31-40), Plaboratory accreditation status (P=0.081). A considerable percentage of laboratory technicians in Croatian medical laboratories do not comply with safety measures. Lack of compliance is observed in all personnel regardless laboratory accreditation and participants' age. However, those working in private laboratories adhere more to the code of conduct.

Systems study 'Alternative Entsorgung'. Final report. Technical annex 6

International Nuclear Information System (INIS)

1984-08-01

In the conditioning plant, fuel elements which have been stored for ten years are loaded into transport containers, unloaded, identified and welded into a dry storage box. The dry store barrel is introduced into a final storage container, which, after being closed, is packed in lost shielding. This so-called final storage barrel is finally placed in a transport container and leaves the conditioning plant in this form by rail for transport to the final storage mine. The fuel element method of treatment 'packing of three complete fuel elements' was used as the reference process. In addition, the method of treatment 'fuel elements dismantled into fuel rods' was also examined. The handling of fuel elements and secondary waste treatment in the reference process are described in detail. (orig./HP) [de

Field studies of radionuclide transport at the Chalk River Laboratories

International Nuclear Information System (INIS)

Champ, D.R.; Killey, R.W.D.; Moltyaner, G.L.

1991-01-01

In this paper the authors summarize the results of: in situ field column experiments to study the transport behaviour of several long-lived radionuclides, 4 natural gradient non-reactive radiotracer injection experiments at the Chalk River Laboratories (CRL) Twin Lake Tracer Test Site, and a model validation study that used data for 90 Sr from two well-defined contaminated groundwater flow systems at CRL. The paper also describes a current re-evaluation of radionuclide release and transport from a 1960 experimental burial (in a CRL sand aquifer) of glass blocks containing fission and activation products. (J.P.N.)

Troubles for the sustainability of the quality assurance in the laboratories of radiological control in Peru

International Nuclear Information System (INIS)

Gonzales, Susana; Lopez, Edith

2008-01-01

Full text: The Nuclear Energy Peruvian Institute (IPEN) has laboratories which offer services of radiological control. Radiometric analysis in raw and processed foodstuff is requested by several enterprises of both public and private sectors which uses the results for trading purposes like exportation, importation and licitations. The service of assays and calibration with reliable results has become a need due to the external audits performed by accredited laboratories to fulfil the requirements of the Peruvian standard organism. With the support of the International Atomic Energy Agency (IAEA), the IPEN laboratory of radiometric analysis implemented its quality system in 2001 under the ISO IEC 17025 Standard 'General Requirements for the Competence of the Calibration and Testing Laboratories' with the purpose to organize the activities and offer an enhanced service to the clients. The implementation of the quality system has allowed giving a better service with enhanced efficiency to the clients, assuring the reliability of the final output, the analytical results. It had been possible since the laboratories have participated in worldwide proficiency tests sponsored by the IAEA and currently work with reference material. The quality system allows identifying potential faults in any stage of the process in order to prevent any problem in the final output, assuring the appropriate quality of the issued analytical results and to take the necessary corrective actions to avoid those events to happen again. This study has identified and assessed several difficulties and troubles which prevent to fulfil the requirements of the Quality Standard and as a consequence, disable the sustainability of the quality systems and prevent the accreditation. Several proposals and solution alternatives which involve the Executive Staff and the proactive participation of the personnel are presented. (author)

Additional EIPC Study Analysis. Final Report

Energy Technology Data Exchange (ETDEWEB)

Hadley, Stanton W [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Gotham, Douglas J. [Purdue Univ., West Lafayette, IN (United States); Luciani, Ralph L. [Navigant Consultant Inc., Suwanee, GA (United States)

2014-12-01

Between 2010 and 2012 the Eastern Interconnection Planning Collaborative (EIPC) conducted a major long-term resource and transmission study of the Eastern Interconnection (EI). With guidance from a Stakeholder Steering Committee (SSC) that included representatives from the Eastern Interconnection States Planning Council (EISPC) among others, the project was conducted in two phases. Phase 1 involved a long-term capacity expansion analysis that involved creation of eight major futures plus 72 sensitivities. Three scenarios were selected for more extensive transmission- focused evaluation in Phase 2. Five power flow analyses, nine production cost model runs (including six sensitivities), and three capital cost estimations were developed during this second phase. The results from Phase 1 and 2 provided a wealth of data that could be examined further to address energy-related questions. A list of 14 topics was developed for further analysis. This paper brings together the earlier interim reports of the first 13 topics plus one additional topic into a single final report.

Critical and strategic materials proceedings of the laboratory study group meeting

International Nuclear Information System (INIS)

1983-06-01

These Proceedings serve to identify the appropriate role for the DOE-BES-DMS Laboratory program concerning critical and strategic materials, identify and articulate high priority DOE-BES-DMS target areas so as to maximize programmatic responsiveness to national needs concerning critical and strategic materials, and identify research, expertise, and resources (including Collaborative Research Centers) that are relevant to critical and strategic materials that is either underway or in place under the DOE-BES-DMS Laboratory program. Laboratory statements of collaborative research are given

Final report on CCQM-K27.2: Second Subsequent study: determination of ethanol in aqueous media

Science.gov (United States)

Schantz, Michele M.; Parris, Reenie M.; May, Willie E.; Rosso, Adriana; Puglisi, Celia; Marques Rodrigues Caixeiro, Janaína; Massiff, Gabriela; Camacho Frías, Evangelina; Pérez Urquiza, Melina; Archer, Marcellé; Visser, M. S.; deVos, Betty-Jayne

2013-01-01

subsequent study (nominal concentrations of 0.2 mg/g, 1 mg/g, 3 mg/g and 60 mg/g). The three participants in the CCQM-K27-Subsequent key comparison demonstrated their ability to measure ethanol in aqueous matrix in the concentration range of 0.2 mg/g to 60 mg/g. A report on this project has been approved by the CCQM and can be found at the BIPM website. A second follow-on key comparison, CCQM-K27.2 Second Subsequent, was initiated in 2006 to accommodate laboratories that had not been ready to benchmark their methods in the previous two CCQM-K27 studies. Two levels of ethanol in water were used in the second subsequent study ranging in concentration between 0.5 mg/g and 4 mg/g. Four of the five participants in the CCQM-K27.2 Second Subsequent key comparison demonstrated their ability to measure ethanol in aqueous matrix in that concentration range. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Cassini's Grand Finale Science Highlights

Science.gov (United States)

Spilker, Linda

2017-10-01

After 13 years in orbit, the Cassini-Huygens Mission to Saturn ended in a science-rich blaze of glory. Cassini returned its final bits of unique science data on September 15, 2017, as it plunged into Saturn's atmosphere satisfying planetary protection requirements. Cassini's Grand Finale covered a period of roughly five months and ended with the first time exploration of the region between the rings and planet.The final close flyby of Titan in late April 2017 propelled Cassini across Saturn’s main rings and into its Grand Finale orbits; 22 orbits that repeatedly dove between Saturn’s innermost rings and upper atmosphere making Cassini the first spacecraft to explore this region. The last orbit turned the spacecraft into the first Saturn upper atmospheric probe.The Grand Finale orbits provided highest resolution observations of both the rings and Saturn, and in-situ sampling of the ring particle composition, Saturn's atmosphere, plasma, and innermost radiation belts. The gravitational field was measured to unprecedented accuracy, providing information on the interior structure of the planet, winds in the deeper atmosphere, and mass of the rings. The magnetic field provided insight into the physical nature of the magnetic dynamo and structure of the internal magnetic field. The ion and neutral mass spectrometer sampled the upper atmosphere for molecules that escape the atmosphere in addition to molecules originating from the rings. The cosmic dust analyzer directly sampled the composition from different parts of the main rings for the first time. Fields and particles instruments directly measured the plasma environment between the rings and planet.Science highlights and new mysteries gleaned to date from the Grand Finale orbits will be discussed.The research described in this paper was carried out in part at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with the National Aeronautics and Space Administration. Copyright 2017

Inter-laboratory comparison study of gamma cameras in Pakistan

International Nuclear Information System (INIS)

Shahid, M.A.; Mumtaz-ul-Haq

1988-01-01

The evaluation of the performance of both instrument and the physician are important in any quality assurance programme in nuclear medicine imaging. The IAEA launched a similar program in 1984 under its Regional Cooperation Agreement program in South Asian Countries. The first part of the study consisted of the evaluation of imaging equipment by imaging IAEA-WHO Simulated Anatomic Liver Phantom (SALP) and its interpretation by the physician. From Pakistan, 8 gamma cameras from 7 laboratories were used for the study and 16 physician interpreted in the SALP images. This paper reports the results of SALP images from Pakistan and shows the efficacy of 80 to 100% as regards the quality of image obtained and the interpretation done by the physicians. (author)

Closing the brain-to-brain loop in laboratory testing.

Science.gov (United States)

Plebani, Mario; Lippi, Giuseppe

2011-07-01

Abstract The delivery of laboratory services has been described 40 years ago and defined with the foremost concept of "brain-to-brain turnaround time loop". This concept consists of several processes, including the final step which is the action undertaken on the patient based on laboratory information. Unfortunately, the need for systematic feedback to improve the value of laboratory services has been poorly understood and, even more risky, poorly applied in daily laboratory practice. Currently, major problems arise from the unavailability of consensually accepted quality specifications for the extra-analytical phase of laboratory testing. This, in turn, does not allow clinical laboratories to calculate a budget for the "patient-related total error". The definition and use of the term "total error" refers only to the analytical phase, and should be better defined as "total analytical error" to avoid any confusion and misinterpretation. According to the hierarchical approach to classify strategies to set analytical quality specifications, the "assessment of the effect of analytical performance on specific clinical decision-making" is comprehensively at the top and therefore should be applied as much as possible to address analytical efforts towards effective goals. In addition, an increasing number of laboratories worldwide are adopting risk management strategies such as FMEA, FRACAS, LEAN and Six Sigma since these techniques allow the identification of the most critical steps in the total testing process, and to reduce the patient-related risk of error. As a matter of fact, an increasing number of laboratory professionals recognize the importance of understanding and monitoring any step in the total testing process, including the appropriateness of the test request as well as the appropriate interpretation and utilization of test results.

Chemistry Laboratory

Data.gov (United States)

Federal Laboratory Consortium — Purpose: To conduct fundamental studies of highway materials aimed at understanding both failure mechanisms and superior performance. New standard test methods are...

Lawrence Livermore National Laboratory FY 2016 Laboratory Directed Research and Development Annual Report

Energy Technology Data Exchange (ETDEWEB)

Al-Ayat, R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Gard, E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Sketchley, J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Watkins, L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2017-10-16

The LDRD annual report for FY2016 consists of two parts: The Overview. This section contains a broad description of the LDRD Program, highlights of recent accomplishments and awards, Program statistics, and the LDRD portfolio-management processes. Project Reports. Project reports are submitted by all principal investigators at the end of the fiscal year. The length and depth of the report depends on the project’s lifecycle. For projects that will be continuing the following year, the principal investigator submits a continuing project report, which is a brief update containing descriptions of the goals, scope, motivation, relevance (to DOE/NNSA and Livermore mission areas), and technical progress achieved in FY16, as well as a list of selected publications and presentations that resulted from the research. For projects that concluded in FY16, a more detailed final report is provided that is technical in nature and includes the background, objectives, scientific approach, accomplishments, and impacts on the Laboratory missions, as well as a list of publications and presentations that resulted from the research. Project reports are listed under their research topics and organized by year and type, such as exploratory research (ER), feasibility study (FS), laboratory-wide competition (LW), and strategic initiative (SI). Each project is assigned a unique tracking code, an identifier that consists of three elements. The first is the fiscal year in which the project began, the second represents the project type, and the third identifies the serial number of the project for that fiscal year. For example, 16-ERD-100 means the project is an exploratory research project that began in FY16. The three-digit number (100) represents the serial number for the project.

Laboratory Studies of Larval Cannibalism in ’Toxorhynchites amboinensis’ (Diptera: Culicidae)

Science.gov (United States)

1990-09-01

1986. However, there have been few laboratory studies Container Volume. Eggs of Tx. amboinensis of the phenomenon. Rubio & Avesta (1984) sug- were...predator ratio and frequency of cannibalism, as competition for food may limit growth. Alterna- proposed by Rubio & Avesta (1984). A careful ex- tively, the

A FMEA clinical laboratory case study: how to make problems and improvements measurable.

Science.gov (United States)

Capunzo, Mario; Cavallo, Pierpaolo; Boccia, Giovanni; Brunetti, Luigi; Pizzuti, Sante

2004-01-01

The authors have experimented the application of the Failure Mode and Effect Analysis (FMEA) technique in a clinical laboratory. FMEA technique allows: a) to evaluate and measure the hazards of a process malfunction, b) to decide where to execute improvement actions, and c) to measure the outcome of those actions. A small sample of analytes has been studied: there have been determined the causes of the possible malfunctions of the analytical process, calculating the risk probability index (RPI), with a value between 1 and 1,000. Only for the cases of RPI > 400, improvement actions have been implemented that allowed a reduction of RPI values between 25% to 70% with a costs increment of FMEA technique can be applied to the processes of a clinical laboratory, even if of small dimensions, and offers a high potential of improvement. Nevertheless, such activity needs a thorough planning because it is complex, even if the laboratory already operates an ISO 9000 Quality Management System.

Process in Developing Zebra fish Laboratory at Malaysian Nuclear Agency for Toxicology Studies

International Nuclear Information System (INIS)

Fazliana Mohd Saaya; Mohd Noor Hidayat Adenan; Anee Suryani Sued

2015-01-01

Toxicology is a branch of the very important especially in determining the safety and effectiveness of herbal products to avoid any side effects to the user. Currently, toxicity tests conducted in the laboratory is testing the toxicity of shrimp, tests on cell cultures and experimental animal tests on the rats. One of the most recent exam easier and can reduce the use of experimental rats was testing on zebra fish fish. Fish zebra fish Danio rerio, suitable for the study of toxicity, teratogenicity, genetic, oncology and neurobiology. Zebra fish system of aquarium fish zebra fish system has been in Nuclear Malaysia since 2013 but has not yet fully operational due to several factors and is in the process of moving into a new laboratory which systematically and in accordance with the enabling environment for care. The development of a new fully equipped laboratory is expected to benefit all for use in research. (author)

Final report. [Nonlinear magnetohydrodynamics

International Nuclear Information System (INIS)

Montgomery, D.C.

1998-01-01

This is a final report on the research activities carried out under the above grant at Dartmouth. During the period considered, the grant was identified as being for nonlinear magnetohydrodynamics, considered as the most tractable theoretical framework in which the plasma problems associated with magnetic confinement of fusion plasmas could be studied. During the first part of the grant's lifetime, the author was associated with Los Alamos National Laboratory as a consultant and the work was motivated by the reversed-field pinch. Later, when that program was killed at Los Alamos, the problems became ones that could be motivated by their relation to tokamaks. Throughout the work, the interest was always on questions that were as fundamental as possible, compatible with those motivations. The intent was always to contribute to plasma physics as a science, as well as to the understanding of mission-oriented confined fusion plasmas. Twelve Ph.D. theses were supervised during this period and a comparable number of postdoctoral research associates were temporarily supported. Many of these have gone on to distinguished careers, though few have done so in the context of the controlled fusion program. Their work was a combination of theory and numerical computation, in gradually less and less idealized settings, moving from rectangular periodic boundary conditions in two dimensions, through periodic straight cylinders and eventually, before the grant was withdrawn, to toroids, with a gradually more prominent role for electrical and mechanical boundary conditions. The author never had access to a situation where he could initiate experiments and relate directly to the laboratory data he wanted. Computers were the laboratory. Most of the work was reported in referred publications in the open literature, copies of which were transmitted one by one to DOE at the time they appeared. The Appendix to this report is a bibliography of published work which was carried out under the

Laboratory study of orographic cloud-like flow

Science.gov (United States)

Singh, Kanwar Nain; Sreenivas, K. R.

2013-11-01

Clouds are one of the major sources of uncertainty in climate prediction, listed in ``the most urgent scientific problems requiring attention'' IPCC. Also, convective clouds are of utmost importance to study the dynamics of tropical meteorology and therefore, play a key role in understanding monsoons. The present work is to study the dynamics of orographic clouds. Parameterization of these clouds will help in forecasting the precipitation accurately. Also, one could validate laboratory results from our study by actually measuring cloud development along a sloping terrain. In this context a planar buoyant turbulent wall jet is considered as an appropriate low order fluid-dynamical model for studying the turbulence and entrainment in orographic-clouds. Flow is volumetrically heated to mimic the latent heat release due to condensation in an actual cloud. This is the first step in studying the entrainment dynamics of the evolving orographic cloud. We are going to present some results on the cloud development using techniques that allows us to construct a 3-dimensional flow field at each instance and its development over the time. By combining velocity field from PIV and flow volume from PLIF at successive instances, we estimate the entrainment coefficient. Since the life-cycle of a cloud is determined by the entrainment of ambient air, these results could be extremely helpful in understanding the dynamics of the clouds. Detailed results will be presented at the conference.

Elemental Characterization of Soil and Sediment Using NAA Technique for BATAN Inter Laboratory Comparison

International Nuclear Information System (INIS)

Syukria Kurniawati; Diah Dwiana Lestiani; Natalia Adventini

2009-01-01

Elemental characterization of soil and sediment samples using neutron activation analysis (NAA) for BATAN inter laboratory comparison have been conducted. TAR laboratory have been accredited by KAN since 2006, participating the test to evaluate and maintain its capability as testing laboratory that implemented ISO/IEC 17025. Samples from PTBIN were dried at 110°C for 2 hours and homogenized. The samples were irradiated at rabbit system of Multi-Purpose Reactor G.A Siwabessy for 1, 2, 10 and 60 minutes, then counted using HPGe gamma spectrometer. Several statistical test were applied such as μ-test, relative deviation, acceptance criteria for accuracy and precision. The result showed that soil contains V, Al, Ca, Mn, Na, K, As, Fe, Zn and Hg. From accuracy and precision, final status for 9 elements were passed but Ca was rejected, while V, Al, Mn, Cr, Fe, Zn and Co were detected in sediment samples. Final status for V, Al, Mn, Cr, Fe and Co elements were passed but Zn was rejected. (author)

The laboratories of geological studies; Les laboratoires d`etudes geologiques

Energy Technology Data Exchange (ETDEWEB)

NONE

1994-01-01

This educational document comprises 4 booklets in a folder devoted to the presentation of the ANDRA`s activities in geological research laboratories. The first booklet gives a presentation of the missions of the ANDRA (the French agency for the management of radioactive wastes) in the management of long life radioactive wastes. The second booklet describes the approach of waste disposal facilities implantation. The third booklet gives a brief presentation of the scientific program concerning the underground geologic laboratories. The last booklet is a compilation of questions and answers about long-life radioactive wastes, the research and works carried out in geologic laboratories, the public information and the local socio-economic impact, and the storage of radioactive wastes in deep geological formations. (J.S.)

Determination of Flow Resistance Coefficient for Vegetation in Open Channel: Laboratory study

Science.gov (United States)

Aliza Ahmad, Noor; Ali, ZarinaMd; Arish, Nur Aini Mohd; Munirah Mat Daud, Azra; Fatin Amirah Alias, Nur

2018-04-01

This study focused on determination of flow resistances coefficient for grass in an open channel. Laboratory works were conducted to examine the effects of varying of roughness elements on the flume to determine flow resistance coefficient and also to determine the optimum flow resistance with five different flow rate, Q. Laboratory study with two type of vegetation which are Cow Grass and Pearl Grass were implementing to the bed of a flume. The roughness coefficient, n value is determine using Manning’s equation while Soil Conservation Services (SCS) method was used to determine the surface resistance. From the experiment, the flow resistance coefficient for Cow Grass in range 0.0008 - 0.0039 while Pearl Grass value for the flow resistance coefficient are in between 0.0013 - 0.0054. As a conclusion the vegetation roughness value in open channel are depends on density, distribution type of vegetation used and physical characteristic of the vegetation itself

Physics laboratory 2

International Nuclear Information System (INIS)

1980-01-01

The report covers the research activities of the Physics laboratory of H.C. Oersted Institute, University of Copenhagen in the period January 1, 1976 - January 1, 1979. It gives also an idea about the teaching carried out by yhe laboratory. The research - broadly speaking - deals mainly with the interaction of particles (ions, electrons and neutrons) and electromagnetic radiation (X-rays) with matter. Use is made in studies of: atomic physics, radiation effects, surface physics, the electronic and crystallographic structure of matter and some biological problems. The research is carried out partly in the laboratory itself and partly at and in collaboration with other institutes in this country (H.C. Oersted Institute, Chemical Laboratories, Denmark's Technical University, Aarhus University, Institute of Physics and Risoe National Laboratory) and abroad (Federal Republic of Germany, France, India, Sweden, U.K., U.S.A. and U.S.S.R.). All these institutes are listed in the abstract titles. Bibliography comprehends 94 publications. A substantial part of the research is supported by the Danish Natural Sciences Research Council. (author)

Effect of skill laboratory training on academic performance of medical students.

Science.gov (United States)

Khan, Muhammad Alamgir; Shabbir, Faizania; Qamar, Khadija; Rajput, Tausif Ahmed

2017-05-01

To observe the effect of skill lab training on academic performance of final year medical students in terms of marks obtained in long case, short case, objective structured clinical examination and viva. The cross-sectional comparative study was conducted at Army Medical College, Rawalpindi from February to April 2015. Two batches of final year MBBS were recruited for the study. Batch 1 received conventional training, and Batch 2 received skill lab training. The performance of students was assessed by comparing the marks obtained in long case, short case, objective structured clinical examination and viva. Data was analysed using SPSS 23. Of the 335 subjects, 168(50.1%) were male and 167(49.9%) were female students with a mean age of 21.79±1.02 years. Batch 1 had 151(45%) students and Batch 2 had 184(55%). Batch 2 got significantly higher marks in long case, short case and objective structured clinical examination (p0.05). Acquisition of clinical skills significantly improved when medial students were trained in skill laboratories.

Baccalaureate nursing students' perspectives of peer tutoring in simulation laboratory, a Q methodology study.

Science.gov (United States)

Li, Ting; Petrini, Marcia A; Stone, Teresa E

2018-02-01

The study aim was to identify the perceived perspectives of baccalaureate nursing students toward the peer tutoring in the simulation laboratory. Insight into the nursing students' experiences and baseline data related to their perception of peer tutoring will assist to improve nursing education. Q methodology was applied to explore the students' perspectives of peer tutoring in the simulation laboratory. A convenience P-sample of 40 baccalaureate nursing students was used. Fifty-eight selected Q statements from each participant were classified into the shape of a normal distribution using an 11-point bipolar scale form with a range from -5 to +5. PQ Method software analyzed the collected data. Three discrete factors emerged: Factor I ("Facilitate or empower" knowledge acquisition), Factor II ("Safety Net" Support environment), and Factor III ("Mentoring" learn how to learn). The findings of this study support and indicate that peer tutoring is an effective supplementary strategy to promote baccalaureate students' knowledge acquisition, establishing a supportive safety net and facilitating their abilities to learn in the simulation laboratory. Copyright © 2017 Elsevier Ltd. All rights reserved.

Final Report - Los Alamos National Laboratory Compuational Physics Summer Student Workshop

Energy Technology Data Exchange (ETDEWEB)

Lung, Tyler B. [Los Alamos National Laboratory; Roe, Phil [University of Michigan; Morgan, Nathaniel R. [Los Alamos National Laboratory

2012-08-15

The numerical solution of highly compressible, multi-material flows is an ongoing research area. These types of flows can be solved with a Lagrangian type mesh which moves with the material in a simulation to allow precise material interface tracking. Currently, researchers at Los Alamos National Laboratory and elsewhere are investigating cell-centered Lagrangian algorithms with the aim of producing methods that have second-order accuracy, preserve symmetry, and do not generate spurious vorticity. The new cell-centered algorithms solve a Riemann-like problem at the vertex of a cell. Professor Phil Roe at the University of Michigan has proposed a new struture for Lagrangian hydrodynamic algorithms that does not rely on the solution of the Riemann problem. The new approach utilizes Flux Corrected Transport (FCT) and it implements a form of vorticity control. The first step in the development of this method has been to construct an algorithm that solves the acoustic equations on an Eulerian mesh. The algorithm, which builds on the work of Morton and Roe [1], calculates fluxes at cell vertices, attains second-order accuracy using FCT, and has the special property of preserving vorticity. Results are presented that confirm the second order accuracy of the scheme and the vorticity preserving properties. The results are compared to the output produced by a MUSCL-Hancock algorithm. Some discussion of limiting methods for the FCT algorithm is also given.

Final design of the neutral beam lines for the Tokamak Fusion Test Reactor

International Nuclear Information System (INIS)

Pittenger, L.C.; Valby, L.E.; Stone, R.R.; Pedrotti, L.R.; Denhoy, B.; Yoard, R.

1979-01-01

Final design of the neutral beam lines for TFTR has been completed. A prototype has been assembled at Lawrence Berkeley Laboratory and is undergoing testing as part of the Neutral Beam System Test Facility (NBSTF). The final neutral beam line (NBL) configuration differs in several details from that previously reported upon; certain components have been added; and testing of the cryopump system has led to some design simplification. It is these developments which are reported herein

Final Safety Analysis Document for Building 693 Chemical Waste Storage Building at Lawrence Livermore National Laboratory

International Nuclear Information System (INIS)

Salazar, R.J.; Lane, S.

1992-02-01

This Safety Analysis Document (SAD) for the Lawrence Livermore National Laboratory (LLNL) Building 693, Chemical Waste Storage Building (desipated as Building 693 Container Storage Unit in the Laboratory's RCRA Part B permit application), provides the necessary information and analyses to conclude that Building 693 can be operated at low risk without unduly endangering the safety of the building operating personnel or adversely affecting the public or the environment. This Building 693 SAD consists of eight sections and supporting appendices. Section 1 presents a summary of the facility designs and operations and Section 2 summarizes the safety analysis method and results. Section 3 describes the site, the facility desip, operations and management structure. Sections 4 and 5 present the safety analysis and operational safety requirements (OSRs). Section 6 reviews Hazardous Waste Management's (HWM) Quality Assurance (QA) program. Section 7 lists the references and background material used in the preparation of this report Section 8 lists acronyms, abbreviations and symbols. Appendices contain supporting analyses, definitions, and descriptions that are referenced in the body of this report

Anisotropic Rotational Diffusion Studied by Nuclear Spin Relaxation and Molecular Dynamics Simulation: An Undergraduate Physical Chemistry Laboratory

Science.gov (United States)

Fuson, Michael M.

2017-01-01

Laboratories studying the anisotropic rotational diffusion of bromobenzene using nuclear spin relaxation and molecular dynamics simulations are described. For many undergraduates, visualizing molecular motion is challenging. Undergraduates rarely encounter laboratories that directly assess molecular motion, and so the concept remains an…

Tank 241-T-204, core 188 analytical results for the final report

Energy Technology Data Exchange (ETDEWEB)

Nuzum, J.L.

1997-07-24

TANK 241-T-204, CORE 188, ANALYTICAL RESULTS FOR THE FINAL REPORT. This document is the final laboratory report for Tank 241 -T-204. Push mode core segments were removed from Riser 3 between March 27, 1997, and April 11, 1997. Segments were received and extruded at 222-8 Laboratory. Analyses were performed in accordance with Tank 241-T-204 Push Mode Core Sampling and analysis Plan (TRAP) (Winkleman, 1997), Letter of instruction for Core Sample Analysis of Tanks 241-T-201, 241- T-202, 241-T-203, and 241-T-204 (LAY) (Bell, 1997), and Safety Screening Data Qual@ Objective (DO) ODukelow, et al., 1995). None of the subsamples submitted for total alpha activity (AT) or differential scanning calorimetry (DC) analyses exceeded the notification limits stated in DO. The statistical results of the 95% confidence interval on the mean calculations are provided by the Tank Waste Remediation Systems Technical Basis Group and are not considered in this report.

LAPP - Annecy le Vieux Particle Physics Laboratory. Activity report 1996-1997

International Nuclear Information System (INIS)

Colas, Jacques; Minard, Marie-Noelle; Decamp, Daniel; Marion, Frederique; Drancourt, Cyril; Riva, Vanessa; Berger, Nicole; Bombar, Claudine; Dromby, Gerard

2004-01-01

LAPP is a high energy physics laboratory founded in 1976 and is one of the 19 laboratories of IN2P3 (National Institute of Nuclear and particle physics), institute of CNRS (National Centre for Scientific Research). LAPP is joint research facility of the University Savoie Mont Blanc (USMB) and the CNRS. Research carried out at LAPP aims at understanding the elementary particles and the fundamental interactions between them as well as exploring the connections between the infinitesimally small and the unbelievably big. Among other subjects LAPP teams try to understand the origin of the mass of the particles, the mystery of dark matter and what happened to the anti-matter that was present in the early universe. LAPP researchers work in close contact with phenomenologist teams from LAPTh, a theory laboratory hosted in the same building. LAPP teams also work since several decades at understanding the neutrinos, those elementary almost massless particles with amazing transformation properties. They took part in the design and realization of several experiments. Other LAPP teams collaborate in experiments studying signals from the cosmos. This document presents the activities of the laboratory during the years 1996-1997: 1 - Presentation of LAPP; 2 - Data acquisition experiments: e"+e"- annihilations at LEP (standard model and beyond the standard model - ALEPH, Study of hadronic final state events and Search for supersymmetric particles at L3 detector); Neutrino experiments (neutrino oscillation search at 1 km of the Chooz reactors, search for neutrino oscillations at the CERN Wide Band neutrino beam - NOMAD); Quarks-Gluons plasma; Hadronic spectroscopy; 3 - Experiments under preparation (CP violation study - BABAR, Anti Matter Spectrometer in Space - AMS, Search for gravitational waves - VIRGO, Search for the Higgs boson - ATLAS and CMS); 4 - Technical departments; 5 - Theoretical physics; 6 - Other activities

Decontamination and decommissioning of 61 plutonium gloveboxes in D-Wing, Building 212 Argonne National Laboratory-East: Final project report

International Nuclear Information System (INIS)

Cheever, C.L.; Rose, R.W.

1996-09-01

Argonne National Laboratory-East (ANL-E) is a government-owned, contractor operated, multipurpose research facility located 25 miles southwest of downtown Chicago on 689 hectares (1,700 acres) in DuPage County, Illinois, as shown in Figure 1.1. Building 212 is located in the central area of ANL-E, as shown in Figure 1.2. The purpose of this project was to eliminate the risk of radioactive material release from the contaminated glovebox systems and to make the laboratories available for unrestricted use. The following work objectives were established: (1) Identify and remove radioactive materials for return to ANL-E Special Materials control. (2) Remove and package the radioactively contaminated materials and equipment from the gloveboxes. (3) Decontaminate the gloveboxes to nontransuranic (non-TRU) levels. (4) Size-reduce and package the gloveboxes and support systems. (5) Document and dispose of the radioactive and mixed waste. (6) Decontaminate, survey, and release the nine laboratories and corridor areas for unrestricted use

Study of nasal swipe analysis methods at Los Alamos National Laboratory

International Nuclear Information System (INIS)

Metcalf, R.A.

1996-01-01

The Health Physics Analysis Laboratory (HPAL) performs around 30,000 nasal swipe analyses for transuranic nuclides each year in support of worker health and safety at the Los Alamos National Laboratory (LANL). The analysis method used employs cotton swabs swiped inside a nostril and liquid scintillation analyses of the swabs. The technical basis of this method was developed at LANL and has been in use for over 10 years. Recently, questions regarding the usefulness of a non-homogeneous mixture in liquid scintillation analyses have created a need for re-evaluation of the method. A study of the validity of the method shows it provides reliable, stable, and useful data as an indicator of personnel contamination. The study has also provided insight into the underlying process which occurs to allow the analysis. Further review of this process has shown that similar results can be obtained with different sample matrices, using less material than the current analysis method. This reduction can save HPAL the cost of materials as well as greatly reduce the waste created. Radionuclides of concern include Am-241, Pu-239, and Pu-238

A 2-year study of patient safety competency assessment in 29 clinical laboratories.

Science.gov (United States)

Reed, Robyn C; Kim, Sara; Farquharson, Kara; Astion, Michael L

2008-06-01

Competency assessment is critical for laboratory operations and is mandated by the Clinical Laboratory Improvement Amendments of 1988. However, no previous reports describe methods for assessing competency in patient safety. We developed and implemented a Web-based tool to assess performance of 875 laboratory staff from 29 laboratories in patient safety. Question categories included workplace culture, categorizing error, prioritization of patient safety interventions, strength of specific interventions, and general patient safety concepts. The mean score was 85.0%, with individual scores ranging from 56% to 100% and scores by category from 81.3% to 88.6%. Of the most difficult questions (laboratory technologists. Computer-based competency assessments help laboratories identify topics for continuing education in patient safety.

Vermicomposting of winery wastes: a laboratory study.

Science.gov (United States)

Nogales, Rogelio; Cifuentes, Celia; Benítez, Emilio

2005-01-01

In Mediterranean countries, millions of tons of wastes from viticulture and winery industries are produced every year. This study describes the ability of the earthworm Eisenia andrei to compost different winery wastes (spent grape marc, vinasse biosolids, lees cakes, and vine shoots) into valuable agricultural products. The evolution of earthworm biomass and enzyme activities was tracked for 16 weeks of vermicomposting, on a laboratory scale. Increases in earthworm biomass for all winery wastes proved lower than in manure. Changes in hydrolytic enzymes and overall microbial activities during the vermicomposting process indicated the biodegradation of the winery wastes. Vermicomposting improved the agronomic value of the winery wastes by reducing the C:N ratio, conductivity and phytotoxicity, while increasing the humic materials, nutrient contents, and pH in all cases. Thus, winery wastes show potential as raw substrates in vermicomposting, although further research is needed to evaluate the feasibility of such wastes in large-scale vermicomposting systems.

Improving laboratory data entry quality using Six Sigma.

Science.gov (United States)

Elbireer, Ali; Le Chasseur, Julie; Jackson, Brooks

2013-01-01

The Uganda Makerere University provides clinical laboratory support to over 70 clients in Uganda. With increased volume, manual data entry errors have steadily increased, prompting laboratory managers to employ the Six Sigma method to evaluate and reduce their problems. The purpose of this paper is to describe how laboratory data entry quality was improved by using Six Sigma. The Six Sigma Quality Improvement (QI) project team followed a sequence of steps, starting with defining project goals, measuring data entry errors to assess current performance, analyzing data and determining data-entry error root causes. Finally the team implemented changes and control measures to address the root causes and to maintain improvements. Establishing the Six Sigma project required considerable resources and maintaining the gains requires additional personnel time and dedicated resources. After initiating the Six Sigma project, there was a 60.5 percent reduction in data entry errors from 423 errors a month (i.e. 4.34 Six Sigma) in the first month, down to an average 166 errors/month (i.e. 4.65 Six Sigma) over 12 months. The team estimated the average cost of identifying and fixing a data entry error to be $16.25 per error. Thus, reducing errors by an average of 257 errors per month over one year has saved the laboratory an estimated $50,115 a year. The Six Sigma QI project provides a replicable framework for Ugandan laboratory staff and other resource-limited organizations to promote quality environment. Laboratory staff can deliver excellent care at a lower cost, by applying QI principles. This innovative QI method of reducing data entry errors in medical laboratories may improve the clinical workflow processes and make cost savings across the health care continuum.

Laboratory Spectroscopy of Large Carbon Molecules and Ions in Support of Space Missions. A New Generation of Laboratory & Space Studies

Science.gov (United States)

Salama, Farid; Tan, Xiaofeng; Cami, Jan; Biennier, Ludovic; Remy, Jerome

2006-01-01

Polycyclic Aromatic Hydrocarbons (PAHs) are an important and ubiquitous component of carbon-bearing materials in space. A long-standing and major challenge for laboratory astrophysics has been to measure the spectra of large carbon molecules in laboratory environments that mimic (in a realistic way) the physical conditions that are associated with the interstellar emission and absorption regions [1]. This objective has been identified as one of the critical Laboratory Astrophysics objectives to optimize the data return from space missions [2]. An extensive laboratory program has been developed to assess the properties of PAHs in such environments and to describe how they influence the radiation and energy balance in space. We present and discuss the gas-phase electronic absorption spectra of neutral and ionized PAHs measured in the UV-Visible-NIR range in astrophysically relevant environments and discuss the implications for astrophysics [1]. The harsh physical conditions of the interstellar medium characterized by a low temperature, an absence of collisions and strong VUV radiation fields - have been simulated in the laboratory by associating a pulsed cavity ringdown spectrometer (CRDS) with a supersonic slit jet seeded with PAHs and an ionizing, penning-type, electronic discharge. We have measured for the {\\it first time} the spectra of a series of neutral [3,4] and ionized [5,6] interstellar PAHs analogs in the laboratory. An effort has also been attempted to quantify the mechanisms of ion and carbon nanoparticles production in the free jet expansion and to model our simulation of the diffuse interstellar medium in the laboratory [7]. These experiments provide {\\it unique} information on the spectra of free, large carbon-containing molecules and ions in the gas phase. We are now, for the first time, in the position to directly compare laboratory spectral data on free, cold, PAH ions and carbon nano-sized carbon particles with astronomical observations in the

Summaries of the Idaho National Engineering Laboratory Radioecology and Ecology Program research projects

International Nuclear Information System (INIS)

Markham, O.D.

1987-06-01

This report provides summaries of individual research projects conducted by the Idaho National Engineering Laboratory Radioecology and Ecology Program. Summaries include projects in various stages, from those that are just beginning, to projects that are in the final publication stage

Idaho National Engineering Laboratory site development plan

International Nuclear Information System (INIS)

1994-09-01

This plan briefly describes the 20-year outlook for the Idaho National Engineering Laboratory (INEL). Missions, workloads, worker populations, facilities, land, and other resources necessary to fulfill the 20-year site development vision for the INEL are addressed. In addition, the plan examines factors that could enhance or deter new or expanded missions at the INEL. And finally, the plan discusses specific site development issues facing the INEL, possible solutions, resources required to resolve these issues, and the anticipated impacts if these issues remain unresolved

Portuguese Family Physicians' Awareness of Diagnostic and Laboratory Test Costs: A Cross-Sectional Study.

Directory of Open Access Journals (Sweden)

Luísa Sá

Full Text Available Physicians' ability to make cost-effective decisions has been shown to be affected by their knowledge of health care costs. This study assessed whether Portuguese family physicians are aware of the costs of the most frequently prescribed diagnostic and laboratory tests.A cross-sectional study was conducted in a representative sample of Portuguese family physicians, using computer-assisted telephone interviews for data collection. A Likert scale was used to assess physician's level of agreement with four statements about health care costs. Family physicians were also asked to estimate the costs of diagnostic and laboratory tests. Each physician's cost estimate was compared with the true cost and the absolute error was calculated.One-quarter (24%; 95% confidence interval: 23%-25% of all cost estimates were accurate to within 25% of the true cost, with 55% (95% IC: 53-56 overestimating and 21% (95% IC: 20-22 underestimating the true actual cost. The majority (76% of family physicians thought they did not have or were uncertain as to whether they had adequate knowledge of diagnostic and laboratory test costs, and only 7% reported receiving adequate education. The majority of the family physicians (82% said that they had adequate access to information about the diagnostic and laboratory test costs. Thirty-three percent thought that costs did not influence their decision to order tests, while 27% were uncertain.Portuguese family physicians have limited awareness of diagnostic and laboratory test costs, and our results demonstrate a need for improved education in this area. Further research should focus on identifying whether interventions in cost knowledge actually change ordering behavior, in identifying optimal methods to disseminate cost information, and on improving the cost-effectiveness of care.

Portuguese Family Physicians’ Awareness of Diagnostic and Laboratory Test Costs: A Cross-Sectional Study

Science.gov (United States)

Sá, Luísa; Costa-Santos, Cristina; Teixeira, Andreia; Couto, Luciana; Costa-Pereira, Altamiro; Hespanhol, Alberto; Santos, Paulo; Martins, Carlos

2015-01-01

Background Physicians’ ability to make cost-effective decisions has been shown to be affected by their knowledge of health care costs. This study assessed whether Portuguese family physicians are aware of the costs of the most frequently prescribed diagnostic and laboratory tests. Methods A cross-sectional study was conducted in a representative sample of Portuguese family physicians, using computer-assisted telephone interviews for data collection. A Likert scale was used to assess physician’s level of agreement with four statements about health care costs. Family physicians were also asked to estimate the costs of diagnostic and laboratory tests. Each physician’s cost estimate was compared with the true cost and the absolute error was calculated. Results One-quarter (24%; 95% confidence interval: 23%–25%) of all cost estimates were accurate to within 25% of the true cost, with 55% (95% IC: 53–56) overestimating and 21% (95% IC: 20–22) underestimating the true actual cost. The majority (76%) of family physicians thought they did not have or were uncertain as to whether they had adequate knowledge of diagnostic and laboratory test costs, and only 7% reported receiving adequate education. The majority of the family physicians (82%) said that they had adequate access to information about the diagnostic and laboratory test costs. Thirty-three percent thought that costs did not influence their decision to order tests, while 27% were uncertain. Conclusions Portuguese family physicians have limited awareness of diagnostic and laboratory test costs, and our results demonstrate a need for improved education in this area. Further research should focus on identifying whether interventions in cost knowledge actually change ordering behavior, in identifying optimal methods to disseminate cost information, and on improving the cost-effectiveness of care. PMID:26356625

FEBEX II Project THG Laboratory Experiments

International Nuclear Information System (INIS)

Missana, T.

2004-01-01

anionic exclusion process and determine the accessible porosity to diffusion at different clay densities. To complete the diffusion coefficients database for the tracers used in the mock-up and in situ tests. The aim of this report is to summarise the main results obtained by all the research groups involved in the THG Laboratory Experiments programme, during the second phase of the FEBEX project. The report will be organised in four main blocks in which the contributions of different institutions will be collected. CIEMAT (Spain), PSI (Switzerland), CSIC (Spain) and VTT (Finland) contributed to the study of the pore water in the clay barrier; CSIC (Spain) contributed to the study of the geochemical processes at the solution/ bentonite interface and to the study of the effects of the interlayer cations on the rheological properties of bentonite. Finally CIEMAT (Spain) and PSI (Switzerland) contributed to investigate radionuclides sorption and migration in bentonite. (Author)

FEBEX II Project THG Laboratory Experiments

Energy Technology Data Exchange (ETDEWEB)

Missana, T.

2004-07-01

anionic exclusion process and determine the accessible porosity to diffusion at different clay densities. To complete the diffusion coefficients database for the tracers used in the mock-up and in situ tests. The aim of this report is to summarise the main results obtained by all the research groups involved in the THG Laboratory Experiments programme, during the second phase of the FEBEX project. The report will be organised in four main blocks in which the contributions of different institutions will be collected. CIEMAT (Spain), PSI (Switzerland), CSIC (Spain) and VTT (Finland) contributed to the study of the pore water in the clay barrier; CSIC (Spain) contributed to the study of the geochemical processes at the solution/ bentonite interface and to the study of the effects of the interlayer cations on the rheological properties of bentonite. Finally CIEMAT (Spain) and PSI (Switzerland) contributed to investigate radionuclides sorption and migration in bentonite. (Author)

Stressful task increases drive for thinness and bulimia: a laboratory study

OpenAIRE

Sassaroli, Sandra; Fiore, Francesca; Mezzaluna, Clarice; Ruggiero, Giovanni Maria

2015-01-01

The scientific literature has suggested that stress undergirds the development of eating disorders (ED). Therefore, this study explored whether laboratory induced stress increases self-reported drive for thinness and bulimic symptoms measured via self-report. The relationship between control, perfectionism, stress, and cognition related to ED was examined using correlational methodology. Eighty-six participants completed an experimental task using a personal computer (PC). All individuals com...

Reducing cognitive load in the chemistry laboratory by using technology-driven guided inquiry experiments

Science.gov (United States)

Hubacz, Frank, Jr.

completed by comparing lab grade averages, final exam averages, and final course grade averages between the two groups. Participant mental effort survey results showed significant positive effects of technology in reducing cognitive load for two laboratory investigations. One investigation revealed a significant difference in achievement measured by lab grade average comparisons. Although results of this study are inconclusive as to the usefulness of technology-driven investigations to affect learning, recommendations for further study are discussed.

The Third International Intercomparison on EPR Tooth Dosimetry: Part 2, final analysis

International Nuclear Information System (INIS)

Wieser, A.; Debuyst, R.; Fattibene, P.; Meghzifene, A.; Onori, S.; Bayankin, S. N.; Brik, A.; Bugay, A.; Chumak, V.; Ciesielski, B.; Hoshi, M.; Imata, H.; Ivannikov, A.; Ivanov, D.; Junczewska, M.; Miyazawa, C.; Penkowski, M.; Pivovarov, S.; Romanyukha, A.; Romanyukha, L.; Schauer, D.; Scherbina, O.; Schultka, K.; Sholom, S.; Skvortsov, V.; Stepanenko, V.; Thomas, J. A.; Tielewuhan, E.; Toyoda, S.; Trompier, F.

2006-01-01

The objective of the Third International Intercomparison on EPR Tooth Dosimetry was to evaluate laboratories performing tooth enamel dosimetry <300 mGy. Final analysis of results included a correlation analysis between features of laboratory dose reconstruction protocols and dosimetry performance. Applicability of electron paramagnetic resonance (EPR) tooth dosimetry at low dose was shown at two applied dose levels of 79 and 176 mGy. Most (9 of 12) laboratories reported the dose to be within 50 mGy of the delivered dose of 79 mGy, and 10 of 12 laboratories reported the dose to be within 100 mGy of the delivered dose of 176 mGy. At the high-dose tested (704 mGy) agreement within 25% of the delivered dose was found in 10 laboratories. Features of EPR dose reconstruction protocols that affect dosimetry performance were found to be magnetic field modulation amplitude in EPR spectrum recording, EPR signal model in spectrum deconvolution and duration of latency period for tooth enamel samples after preparation. (authors)

Solid modeling research at Lawrence Livermore National Laboratory: 1982-1985

International Nuclear Information System (INIS)

Kalibjian, J.R.

1985-01-01

The Lawrence Livermore National Laboratory has sponsored solid modeling research for the past four years to assess this new technology and to determine its potential benefits to the Nuclear Weapons Complex. We summarize here the results of five projects implemented during our effort. First, we have installed two solid modeler codes, TIPS-1 (Technical Information Processing System-1) and PADL-2 (Part and Assembly Description Language), on the Laboratory's CRAY-1 computers. Further, we have extended the geometric coverage and have enhanced the graphics capabilities of the TIPS-1 modeler. To enhance solid modeler performance on our OCTOPUS computer system, we have also developed a method to permit future use of the Laboratory's network video system to provide high-resolution, shaded images at users' locations. Finally, we have begun to implement code that will link solid-modeler data bases to finite-element meshing codes

Studies on waves and turbulence in natural plasmas and in laboratory plasmas

International Nuclear Information System (INIS)

Ferreira, J.L.

1990-09-01

The project for studying plasma waves and plasma turbulence submitted to CAPES to be included in the CAPES/COFECUB international cooperation agreement is presented. The project will be carry out in cooperation with Paris University aiming to simulate in laboratory wave-particle interaction phenomena occuring in space plasma. (M.C.K.)

SENSORY AND CONSUMER TESTING LABORATORY

Data.gov (United States)

Federal Laboratory Consortium — These laboratories conduct a wide range of studies to characterize the sensory properties of and consumer responses to foods, beverages, and other consumer products....

Final Report - Few-Body Studies Using Electromagnetic Interactions

Energy Technology Data Exchange (ETDEWEB)

Norum, Blaine [Univ. of Virginia, Charlottesville, VA (United States). Dept. of Physics

2018-01-25

The work discussed here is an extension of work previously funded by U.S. Department of Energy Grant DE-FG02-97ER41025. Measurements of charged pion photoproduction from deuterium using the Laser Electron Gamma Source (LEGS) at the Brookhaven National Laboratory previously made by us, as members of the LEGS Collaboration, resulted in the most interesting result of two decades of work. By measuring the production of a charged pion (π⁺) in coincidence with an emitted photon we observed structures in the residual two-nucleon system. These indicated the existence of rare, long-lived states not explicable by standard nuclear theory; they suggested a set of configurations not explicable in terms of a nucleon-nucleon pair. The existence of such “exotic” structures has formed the foundation for most of the work that has ensued. Several measurements at various laboratories have supported, but not proved, the existence of these exotic states. The rarity of these states made their existence undetectable in most previous measurements. Only by observing characteristic signatures of such states (i.e., decay photons), by using very specific kinematics which isolate certain reaction products, or by measuring polarization-dependent observables. During the period of this grant we pursued and made progress on the development of experiments to be performed at the High Intensity Gamma Source (HIGS) of the Tri Universities Nuclear Laboratory (TUNL). Our understanding of photon- and electron-induced nuclear reactions depends on understanding of the basic electron and photon interaction. Recently, the issue of two-photon contributions has arisen in the context of deeply inelastic electron scattering. One way to address this is to measure asymmetries in the Bethe-Heitler ee process. We also made progress in developing the detectors required to measure these asymmetries at HIGS. During the last several years the apparent discrepancy between the size of the proton as measured

Collaborative Testing in Practical Laboratories: An Effective Teaching-Learning Method in Histology.

Science.gov (United States)

Guo, Yuping; Li, Enzhong

2016-01-01

This article presents an experimental teaching and learning program used in histology with first-year students in the second term in the Faculty of Biology at Huanghuai University, China. Eighty-six students were divided randomly into two groups (n=43 per group). Tests were conducted at the end of each practical laboratory (10 laboratories in total) in which collaborative testing was used in the experimental group and traditional testing in the control group. To assess achievement, a final examination in histology was carried out at the end of the course. To determine students' attitude to the teaching styles, a questionnaire survey was conducted at the end of the term. Results showed that students preferred the collaborative testing format. In the experimental group, students' scores were significantly higher than those of students in the control group in final examinations. These findings indicate that collaborative testing enhances student learning and understanding of the material taught, and suggest that collaborative testing is an effective teaching-learning method in histology.

Open soundcard as a platform for practical, laboratory study of digital audio

DEFF Research Database (Denmark)

Dimitrov, Smilen; Serafin, Stefania

2014-01-01

This article investigates how lacking suitable platforms for laboratory exercises becomes a learning problem, limiting the practical experience students gain. In engineering education, laboratory demonstration difficulty of issues like real-time streaming in digital signal and audio processing...... afforded by such laboratories, and their open nature, could testably improve the diversity of demonstrated practical topics, while maintaining engineering students' motivation....

Continued development of modeling tools and theory for rf heating. Final report

International Nuclear Information System (INIS)

Smithe, D.N.

1998-01-01

The work performed during the grant has been reported long before this date, specifically in: (1) the grant's annual performance report for 1991, MRC/WDC-R-277; (2) the published AIP Conference Proceedings number-sign 244, Radio Frequency Power in Plasmas, Charleston, SC 1991, ''Evaluation of Wave Dispersion, Mode-Conversion, and Damping for ECRH with Exact Relativistic Corrections,'' by D.N. Smithe and P.L. Colestock; and (3) an unpublished paper entitled ''Temperature Anisotropy and Rotation Upgrades to the ICRF Modules in SNAP and TRANSP'', presented at the 1992 ICRF Modeling and Theory Workshop, at the Princeton Plasma Physics Laboratory. This final report contains copies of number (1). The specifics of the grant's final months' activities, which to the authors recollection have never been reported to the DOE, are as follows. The original grant, which was to terminate August 15, 1991, was extended without additional funds to October 31, 1992. The primary reason for the extension was to permit attendance at the 1992 ICRF Modeling and Theory Workshop at the Princeton Plasma Physics Laboratory (PPPL), which was finally held August 17--18, 1992, after having been rescheduled several times during the summer of 1992. The body of this report contains copies of the 1991 annual report, which gives detailed discussion of the work accomplished

Feasibility study for the computerized automation of the Laboratory Services Branch of EPA Region IV

International Nuclear Information System (INIS)

Boyle, W.G. Jr.; Barton, G.W. Jr.; Taber, L.

1978-01-01

This report is a study of the feasibility of computerized automation of the Laboratory Services Branch of the Environmental Protection Agency's Region IV. The LSB provides chemical analytical support for a number of EPA divisions; its primary function at present is compliance monitoring, field surveys, and oil identification. Automation of the LSB is not only feasible but also highly desirable. Automation systems are proposed that will make major improvements in analytical capacity, quality control, sample management, and reporting capabilities. Most of these automation systems are similar to those already developed and installed at other EPA laboratories. These systems have options that include limited modifications suggested as a result of the study of the LSB Laboratory, and also include communications hardware and software for a Sample File Control host computer. It is estimated that the initial cost of three of the four options considered would be recouped in approximately three years through increased capacity and efficiency of operation

Combined Characterization Techniques to Understand the Stability of a Variety of Organic Photovoltaic Devices - the ISOS-3 inter- laboratory collaboration

DEFF Research Database (Denmark)

Lira-Cantu, Monica; Tanenbaum, David M.; Norrman, Kion

2012-01-01

. The results reported from the combination of the different characterization techniques results in a proposed degradation mechanism. The final conclusion is that the failure of the photovoltaic response of the device with time under full sun solar simulation, is mainly due to the degradation of the electrodes...... and not to the active materials of the solar cell.......This work is part of the inter-laboratory collaboration to study the stability of seven distinct sets of state-of-the-art organic photovoltaic (OPVs) devices prepared by leading research laboratories. All devices have been shipped to and degraded at the Danish Technical University (DTU, formerly...

The challenge of managing laboratory information in a managed care environment.

Science.gov (United States)