WorldWideScience

Sample records for laboratory modeling package

  1. FLEXIBLE FOOD PACKAGING LABORATORY

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory contains equipment to fabricate and test prototype packages of many types and sizes (e.g., bags, pouches, trays, cartons, etc.). This equipment can...

  2. Photolithography and Micro-Fabrication/ Packaging Laboratories

    Data.gov (United States)

    Federal Laboratory Consortium — The Photolithography and Micro-Fabrication/Packaging laboratories provide research level semiconductor processing equipment and facilities that do not require a full...

  3. Inventory of data bases, models, and graphics packages at the Pacific Northwest Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Dionne, P.J.; Mathisen, D.I.

    1978-10-01

    The Information Coordination Focal Point (ICFP) was initiated in FY77 because DOE had a need for improved access to information at the Lawrence Berkeley Laboratory, the Savannah River Laboratory, and the six DOE national laboratories. The task for FY77 was to establish guidelines and procedures for this activity with plans of implementing the procedures in FY78 and FY79. The purpose of this report is to document the progress that has been made during FY78 for this project.

  4. Development of the Symbolic Manipulator Laboratory modeling package for the kinematic design and optimization of the Future Armor Rearm System robot. Ammunition Logistics Program

    Energy Technology Data Exchange (ETDEWEB)

    March-Leuba, S.; Jansen, J.F.; Kress, R.L.; Babcock, S.M. [Oak Ridge National Lab., TN (United States); Dubey, R.V. [Tennessee Univ., Knoxville, TN (United States). Dept. of Mechanical and Aerospace Engineering

    1992-08-01

    A new program package, Symbolic Manipulator Laboratory (SML), for the automatic generation of both kinematic and static manipulator models in symbolic form is presented. Critical design parameters may be identified and optimized using symbolic models as shown in the sample application presented for the Future Armor Rearm System (FARS) arm. The computer-aided development of the symbolic models yields equations with reduced numerical complexity. Important considerations have been placed on the closed form solutions simplification and on the user friendly operation. The main emphasis of this research is the development of a methodology which is implemented in a computer program capable of generating symbolic kinematic and static forces models of manipulators. The fact that the models are obtained trigonometrically reduced is among the most significant results of this work and the most difficult to implement. Mathematica, a commercial program that allows symbolic manipulation, is used to implement the program package. SML is written such that the user can change any of the subroutines or create new ones easily. To assist the user, an on-line help has been written to make of SML a user friendly package. Some sample applications are presented. The design and optimization of the 5-degrees-of-freedom (DOF) FARS manipulator using SML is discussed. Finally, the kinematic and static models of two different 7-DOF manipulators are calculated symbolically.

  5. Development of the Symbolic Manipulator Laboratory modeling package for the kinematic design and optimization of the Future Armor Rearm System robot

    Energy Technology Data Exchange (ETDEWEB)

    March-Leuba, S.; Jansen, J.F.; Kress, R.L.; Babcock, S.M. (Oak Ridge National Lab., TN (United States)); Dubey, R.V. (Tennessee Univ., Knoxville, TN (United States). Dept. of Mechanical and Aerospace Engineering)

    1992-08-01

    A new program package, Symbolic Manipulator Laboratory (SML), for the automatic generation of both kinematic and static manipulator models in symbolic form is presented. Critical design parameters may be identified and optimized using symbolic models as shown in the sample application presented for the Future Armor Rearm System (FARS) arm. The computer-aided development of the symbolic models yields equations with reduced numerical complexity. Important considerations have been placed on the closed form solutions simplification and on the user friendly operation. The main emphasis of this research is the development of a methodology which is implemented in a computer program capable of generating symbolic kinematic and static forces models of manipulators. The fact that the models are obtained trigonometrically reduced is among the most significant results of this work and the most difficult to implement. Mathematica, a commercial program that allows symbolic manipulation, is used to implement the program package. SML is written such that the user can change any of the subroutines or create new ones easily. To assist the user, an on-line help has been written to make of SML a user friendly package. Some sample applications are presented. The design and optimization of the 5-degrees-of-freedom (DOF) FARS manipulator using SML is discussed. Finally, the kinematic and static models of two different 7-DOF manipulators are calculated symbolically.

  6. 77 FR 16551 - Standards for Private Laboratory Analytical Packages and Introduction to Laboratory Related...

    Science.gov (United States)

    2012-03-21

    ... HUMAN SERVICES Food and Drug Administration Standards for Private Laboratory Analytical Packages and Introduction to Laboratory Related Portions of the Food Modernization Safety Act for Private Laboratory... Administration (FDA) is announcing two meetings entitled ``Standards for Private Laboratory Analytical...

  7. Closing the loop on improvement: Packaging experience in the Software Engineering Laboratory

    Science.gov (United States)

    Waligora, Sharon R.; Landis, Linda C.; Doland, Jerry T.

    1994-01-01

    As part of its award-winning software process improvement program, the Software Engineering Laboratory (SEL) has developed an effective method for packaging organizational best practices based on real project experience into useful handbooks and training courses. This paper shares the SEL's experience over the past 12 years creating and updating software process handbooks and training courses. It provides cost models and guidelines for successful experience packaging derived from SEL experience.

  8. Modelling of a DNA packaging motor

    Institute of Scientific and Technical Information of China (English)

    Qian Jun; Xie Ping; Xue Xiao-Guang; Wang Peng-Ye

    2009-01-01

    During the assembly of many viruses, a powerful molecular motor packages the genome into a preassembled capsid. The Bacillus subtilis phage φ29 is an excellent model system to investigate the DNA packaging mechanism because of its highly efficient in vitro DNA packaging activity and the development of a single-molecule packaging assay. Here we make use of structural and biochemical experimental data to build a physical model of DNA packaging by the φ29 DNA packaging motor. Based on the model, various dynamic behaviours such as the packaging rate, pause frequency and slip frequency under different ATP concentrations, ADP concentrations, external loads as well as capsid fillings are studied by using Monte Carlo simulation. Good agreement is obtained between the simulated and available experimental results. Moreover, we make testable predictions that should guide future experiments related to motor function.

  9. The Model 9977 Radioactive Material Packaging Primer

    Energy Technology Data Exchange (ETDEWEB)

    Abramczyk, G. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-10-09

    The Model 9977 Packaging is a single containment drum style radioactive material (RAM) shipping container designed, tested and analyzed to meet the performance requirements of Title 10 the Code of Federal Regulations Part 71. A radioactive material shipping package, in combination with its contents, must perform three functions (please note that the performance criteria specified in the Code of Federal Regulations have alternate limits for normal operations and after accident conditions): Containment, the package must “contain” the radioactive material within it; Shielding, the packaging must limit its users and the public to radiation doses within specified limits; and Subcriticality, the package must maintain its radioactive material as subcritical

  10. Salvus: A flexible high-performance and open-source package for waveform modelling and inversion from laboratory to global scales

    Science.gov (United States)

    Afanasiev, Michael; Boehm, Christian; van Driel, Martin; Krischer, Lion; May, Dave; Rietmann, Max; Fichtner, Andreas

    2017-04-01

    Recent years have been witness to the application of waveform inversion to new and exciting domains, ranging from non-destructive testing to global seismology. Often, each new application brings with it novel wave propagation physics, spatial and temporal discretizations, and models of variable complexity. Adapting existing software to these novel applications often requires a significant investment of time, and acts as a barrier to progress. To combat these problems we introduce Salvus, a software package designed to solve large-scale full-waveform inverse problems, with a focus on both flexibility and performance. Currently based on an abstract implementation of high order finite (spectral) elements, we have built Salvus to work on unstructured quad/hex meshes in both 2 or 3 dimensions, with support for P1-P3 bases on triangles and tetrahedra. A diverse (and expanding) collection of wave propagation physics are supported (i.e. viscoelastic, coupled solid-fluid). With a focus on the inverse problem, functionality is provided to ease integration with internal and external optimization libraries. Additionally, a python-based meshing package is included to simplify the generation and manipulation of regional to global scale Earth models (quad/hex), with interfaces available to external mesh generators for complex engineering-scale applications (quad/hex/tri/tet). Finally, to ensure that the code remains accurate and maintainable, we build upon software libraries such as PETSc and Eigen, and follow modern software design and testing protocols. Salvus bridges the gap between research and production codes with a design based on C++ template mixins and Python wrappers that separates the physical equations from the numerical core. This allows domain scientists to add new equations using a high-level interface, without having to worry about optimized implementation details. Our goal in this presentation is to introduce the code, show several examples across the scales, and

  11. Laboratory of Biological Modeling

    Data.gov (United States)

    Federal Laboratory Consortium — The Laboratory of Biological Modeling is defined by both its methodologies and its areas of application. We use mathematical modeling in many forms and apply it to...

  12. Laboratory of Biological Modeling

    Data.gov (United States)

    Federal Laboratory Consortium — The Laboratory of Biological Modeling is defined by both its methodologies and its areas of application. We use mathematical modeling in many forms and apply it to a...

  13. Dynamic modelling of packaging material flow systems.

    Science.gov (United States)

    Tsiliyannis, Christos A

    2005-04-01

    A dynamic model has been developed for reused and recycled packaging material flows. It allows a rigorous description of the flows and stocks during the transition to new targets imposed by legislation, product demand variations or even by variations in consumer discard behaviour. Given the annual reuse and recycle frequency and packaging lifetime, the model determines all packaging flows (e.g., consumption and reuse) and variables through which environmental policy is formulated, such as recycling, waste and reuse rates and it identifies the minimum number of variables to be surveyed for complete packaging flow monitoring. Simulation of the transition to the new flow conditions is given for flows of packaging materials in Greece, based on 1995--1998 field inventory and statistical data.

  14. Expanded Content Envelope For The Model 9977 Packaging

    Energy Technology Data Exchange (ETDEWEB)

    Abramczyk, G. A.; Loftin, B. M.; Nathan, S. J.; Bellamy, J. S.

    2013-07-30

    An Addendum was written to the Model 9977 Safety Analysis Report for Packaging adding a new content consisting of DOE-STD-3013 stabilized plutonium dioxide materials to the authorized Model 9977 contents. The new Plutonium Oxide Content (PuO{sub 2}) Envelope will support the Department of Energy shipment of materials between Los Alamos National Laboratory and Savannah River Site facilities. The new content extended the current content envelope boundaries for radioactive material mass and for decay heat load and required a revision to the 9977 Certificate of Compliance prior to shipment. The Addendum documented how the new contents/configurations do not compromise the safety basis presented in the 9977 SARP Revision 2. The changes from the certified package baseline and the changes to the package required to safely transport this material is discussed.

  15. Economic tour package model using heuristic

    Science.gov (United States)

    Rahman, Syariza Abdul; Benjamin, Aida Mauziah; Bakar, Engku Muhammad Nazri Engku Abu

    2014-07-01

    A tour-package is a prearranged tour that includes products and services such as food, activities, accommodation, and transportation, which are sold at a single price. Since the competitiveness within tourism industry is very high, many of the tour agents try to provide attractive tour-packages in order to meet tourist satisfaction as much as possible. Some of the criteria that are considered by the tourist are the number of places to be visited and the cost of the tour-packages. Previous studies indicate that tourists tend to choose economical tour-packages and aiming to visit as many places as they can cover. Thus, this study proposed tour-package model using heuristic approach. The aim is to find economical tour-packages and at the same time to propose as many places as possible to be visited by tourist in a given geographical area particularly in Langkawi Island. The proposed model considers only one starting point where the tour starts and ends at an identified hotel. This study covers 31 most attractive places in Langkawi Island from various categories of tourist attractions. Besides, the allocation of period for lunch and dinner are included in the proposed itineraries where it covers 11 popular restaurants around Langkawi Island. In developing the itinerary, the proposed heuristic approach considers time window for each site (hotel/restaurant/place) so that it represents real world implementation. We present three itineraries with different time constraints (1-day, 2-day and 3-day tour-package). The aim of economic model is to minimize the tour-package cost as much as possible by considering entrance fee of each visited place. We compare the proposed model with our uneconomic model from our previous study. The uneconomic model has no limitation to the cost with the aim to maximize the number of places to be visited. Comparison between the uneconomic and economic itinerary has shown that the proposed model have successfully achieved the objective that

  16. DCFPAK: Dose coefficient data file package for Sandia National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Eckerman, K.F.; Leggett, R.W.

    1996-07-31

    The FORTRAN-based computer package DCFPAK (Dose Coefficient File Package) has been developed to provide electronic access to the dose coefficient data files summarized in Federal Guidance Reports 11 and 12. DCFPAK also provides access to standard information regarding decay chains and assembles dose coefficients for all dosimetrically significant radioactive progeny of a specified radionuclide. DCFPAK was designed for application on a PC but, with minor modifications, may be implemented on a UNIX workstation.

  17. Technical Review Report for the Model 9975-96 Package Safety Analysis Report for Packaging (S-SARP-G-00003, Revision 0, January 2008)

    Energy Technology Data Exchange (ETDEWEB)

    West, M

    2009-05-22

    This Technical Review Report (TRR) documents the review, performed by the Lawrence Livermore National Laboratory (LLNL) Staff, at the request of the U.S. Department of Energy (DOE), on the Safety Analysis Report for Packaging, Model 9975, Revision 0, dated January 2008 (S-SARP-G-00003, the SARP). The review includes an evaluation of the SARP, with respect to the requirements specified in 10 CFR 71, and in International Atomic Energy Agency (IAEA) Safety Standards Series No. TS-R-1. The Model 9975-96 Package is a 35-gallon drum package design that has evolved from a family of packages designed by DOE contractors at the Savannah River Site. Earlier package designs, i.e., the Model 9965, the Model 9966, the Model 9967, and the Model 9968 Packagings, were originally designed and certified in the early 1980s. In the 1990s, updated package designs that incorporated design features consistent with the then newer safety requirements were proposed. The updated package designs at the time were the Model 9972, the Model 9973, the Model 9974, and the Model 9975 Packagings, respectively. The Model 9975 Package was certified by the Packaging Certification Program, under the Office of Safety Management and Operations. The safety analysis of the Model 9975-85 Packaging is documented in the Safety Analysis Report for Packaging, Model 9975, B(M)F-85, Revision 0, dated December 2003. The Model 9975-85 Package is certified by DOE Certificate of Compliance (CoC) package identification number, USA/9975/B(M)F-85, for the transportation of Type B quantities of uranium metal/oxide, {sup 238}Pu heat sources, plutonium/uranium metals, plutonium/uranium oxides, plutonium composites, plutonium/tantalum composites, {sup 238}Pu oxide/beryllium metal.

  18. Flexible Rasch Mixture Models with Package psychomix

    Directory of Open Access Journals (Sweden)

    Hannah Frick

    2012-05-01

    Full Text Available Measurement invariance is an important assumption in the Rasch model and mixture models constitute a flexible way of checking for a violation of this assumption by detecting unobserved heterogeneity in item response data. Here, a general class of Rasch mixture models is established and implemented in R, using conditional maximum likelihood estimation of the item parameters (given the raw scores along with flexible specification of two model building blocks: (1 Mixture weights for the unobserved classes can be treated as model parameters or based on covariates in a concomitant variable model. (2 The distribution of raw score probabilities can be parametrized in two possible ways, either using a saturated model or a specification through mean and variance. The function raschmix( in the R package psychomix provides these models, leveraging the general infrastructure for fitting mixture models in the flexmix package. Usage of the function and its associated methods is illustrated on artificial data as well as empirical data from a study of verbally aggressive behavior.

  19. Technical Review Report for the Model 9978-96 Package Safety Analysis Report for Packaging (S-SARP-G-00002, Revision 1, March 2009)

    Energy Technology Data Exchange (ETDEWEB)

    West, M

    2009-03-06

    This Technical Review Report (TRR) documents the review, performed by Lawrence Livermore National Laboratory (LLNL) Staff, at the request of the Department of Energy (DOE), on the 'Safety Analysis Report for Packaging (SARP), Model 9978 B(M)F-96', Revision 1, March 2009 (S-SARP-G-00002). The Model 9978 Package complies with 10 CFR 71, and with 'Regulations for the Safe Transport of Radioactive Material-1996 Edition (As Amended, 2000)-Safety Requirements', International Atomic Energy Agency (IAEA) Safety Standards Series No. TS-R-1. The Model 9978 Packaging is designed, analyzed, fabricated, and tested in accordance with Section III of the American Society of Mechanical Engineers Boiler and Pressure Vessel Code (ASME B&PVC). The review presented in this TRR was performed using the methods outlined in Revision 3 of the DOE's 'Packaging Review Guide (PRG) for Reviewing Safety Analysis Reports for Packages'. The format of the SARP follows that specified in Revision 2 of the Nuclear Regulatory Commission's Regulatory Guide 7.9, i.e., 'Standard Format and Content of Part 71 Applications for Approval of Packages for Radioactive Material'. Although the two documents are similar in their content, they are not identical. Formatting differences have been noted in this TRR, where appropriate. The Model 9978 Packaging is a single containment package, using a 5-inch containment vessel (5CV). It uses a nominal 35-gallon drum package design. In comparison, the Model 9977 Packaging uses a 6-inch containment vessel (6CV). The Model 9977 and Model 9978 Packagings were developed concurrently, and they were referred to as the General Purpose Fissile Material Package, Version 1 (GPFP). Both packagings use General Plastics FR-3716 polyurethane foam as insulation and as impact limiters. The 5CV is used as the Primary Containment Vessel (PCV) in the Model 9975-96 Packaging. The Model 9975-96 Packaging also has the 6CV as its Secondary

  20. PLACE: an open-source python package for laboratory automation, control, and experimentation.

    Science.gov (United States)

    Johnson, Jami L; Tom Wörden, Henrik; van Wijk, Kasper

    2015-02-01

    In modern laboratories, software can drive the full experimental process from data acquisition to storage, processing, and analysis. The automation of laboratory data acquisition is an important consideration for every laboratory. When implementing a laboratory automation scheme, important parameters include its reliability, time to implement, adaptability, and compatibility with software used at other stages of experimentation. In this article, we present an open-source, flexible, and extensible Python package for Laboratory Automation, Control, and Experimentation (PLACE). The package uses modular organization and clear design principles; therefore, it can be easily customized or expanded to meet the needs of diverse laboratories. We discuss the organization of PLACE, data-handling considerations, and then present an example using PLACE for laser-ultrasound experiments. Finally, we demonstrate the seamless transition to post-processing and analysis with Python through the development of an analysis module for data produced by PLACE automation.

  1. Volvo Logistics Corporation Returnable Packaging System : a model for analysing cost savings when switching packaging system

    OpenAIRE

    2008-01-01

    This thesis is a study for analysing costs affected by packaging in a producing industry. The purpose is to develop a model that will calculate and present possible cost savings for the customer by using Volvo Logistics Corporations, VLC’s, returnable packaging instead of other packaging solutions. The thesis is based on qualitative data gained from both theoretical and empirical studies. The methodology for gaining information has been to study theoretical sources such as course literature a...

  2. Oxidation and waste-to-energy output of aluminium waste packaging during incineration: A laboratory study.

    Science.gov (United States)

    López, Félix A; Román, Carlos Pérez; García-Díaz, Irene; Alguacil, Francisco J

    2015-09-01

    This work reports the oxidation behaviour and waste-to-energy output of different semi-rigid and flexible aluminium packagings when incinerated at 850°C in an air atmosphere enriched with 6% oxygen, in the laboratory setting. The physical properties of the different packagings were determined, including their metallic aluminium contents. The ash contents of their combustion products were determined according to standard BS ISO 1171:2010. The net calorific value, the required energy, and the calorific gain associated with each packaging type were determined following standard BS EN 13431:2004. Packagings with an aluminium lamina thickness of >50μm did not fully oxidise. During incineration, the weight-for-weight waste-to-energy output of the packagings with thick aluminium lamina was lower than that of packagings with thin lamina. The calorific gain depended on the degree of oxidation of the metallic aluminium, but was greater than zero for all the packagings studied. Waste aluminium may therefore be said to act as an energy source in municipal solid waste incineration systems. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. Cleanup Verification Package for the 100-F-20, Pacific Northwest Laboratory Parallel Pits

    Energy Technology Data Exchange (ETDEWEB)

    M. J. Appel

    2007-01-22

    This cleanup verification package documents completion of remedial action for the 100-F-20, Pacific Northwest Laboratory Parallel Pits waste site. This waste site consisted of two earthen trenches thought to have received both radioactive and nonradioactive material related to the 100-F Experimental Animal Farm.

  4. Neural Network Program Package for Prosody Modeling

    Directory of Open Access Journals (Sweden)

    J. Santarius

    2004-04-01

    Full Text Available This contribution describes the programme for one part of theautomatic Text-to-Speech (TTS synthesis. Some experiments (for example[14] documented the considerable improvement of the naturalness ofsynthetic speech, but this approach requires completing the inputfeature values by hand. This completing takes a lot of time for bigfiles. We need to improve the prosody by other approaches which useonly automatically classified features (input parameters. Theartificial neural network (ANN approach is used for the modeling ofprosody parameters. The program package contains all modules necessaryfor the text and speech signal pre-processing, neural network training,sensitivity analysis, result processing and a module for the creationof the input data protocol for Czech speech synthesizer ARTIC [1].

  5. Packaging design for Lawrence Berkeley National Laboratory high-resistivity CCDs

    Science.gov (United States)

    Stover, Richard J.; Brown, William E.; Robinson, Lloyd B.; Gilmore, D. K.; Wei, Mingzhi; Lockwood, Christopher

    2004-09-01

    The Lawrence Berkeley National Laboratory has been developing fully-depleted high resistivity CCDs. These CCDs exhibit very high red quantum efficiency, no red fringing, and very low lateral charge diffusion, making them good candidates for astronomical applications that require better red response or better point spread function than can typically be achieved with standard thinned CCDs. For the LBNL 2Kx4K CCD we have developed a four-side mosaic package fabricated from aluminum nitride. Our objectives have been to achieve a flatness of less than 10 micrometers peak-to-valley and a consistent final package thickness variation of 10 micrometers or less in a light-weight package. We have achieved the flatness objective, and we are working toward the thickness variation objective.

  6. Safety analysis report for packaging (SARP) of the Oak Ridge National Laboratory TRU Californium Shipping Container

    Energy Technology Data Exchange (ETDEWEB)

    Klima, B. B.; Shappert, L. B.; Jurgensen, M. C.; Seagren, R. D.; Box, W. D.

    1978-04-01

    An analytical evaluation of the Oak Ridge National Laboratory TRU Californium Shipping Container was made in order to demonstrate its compliance with the regulations governing off-site shipment of packages that contain radioactive material. The evaluation encompassed five primary categories: structural integrity, thermal resistance, radiation shielding, nuclear criticality safety, and quality assurance. The results of the evaluation demonstrate that the container complies with the applicable regulations

  7. Safety evaluation for packaging (onsite) for the Pacific Northwest National Laboratory HEPA filter box

    Energy Technology Data Exchange (ETDEWEB)

    McCoy, J.C.

    1998-07-15

    This safety evaluation for packaging (SEP) evaluates and documents the safe onsite transport of eight high-efficiency particulate air (HEPA) filters in the Pacific Northwest National Laboratory HEPA Filter Box from the 300 Area of the Hanford Site to the Central Waste Complex and on to burial in the 200 West Area. Use of this SEP is authorized for 1 year from the date of release.

  8. topicmodels: An R Package for Fitting Topic Models

    Directory of Open Access Journals (Sweden)

    Bettina Grun

    2011-05-01

    Full Text Available Topic models allow the probabilistic modeling of term frequency occurrences in documents. The fitted model can be used to estimate the similarity between documents as well as between a set of specified keywords using an additional layer of latent variables which are referred to as topics. The R package topicmodels provides basic infrastructure for fitting topic models based on data structures from the text mining package tm. The package includes interfaces to two algorithms for fitting topic models: the variational expectation-maximization algorithm provided by David M. Blei and co-authors and an algorithm using Gibbs sampling by Xuan-Hieu Phan and co-authors.

  9. Power Electronic Packaging Design, Assembly Process, Reliability and Modeling

    CERN Document Server

    Liu, Yong

    2012-01-01

    Power Electronic Packaging presents an in-depth overview of power electronic packaging design, assembly,reliability and modeling. Since there is a drastic difference between IC fabrication and power electronic packaging, the book systematically introduces typical power electronic packaging design, assembly, reliability and failure analysis and material selection so readers can clearly understand each task's unique characteristics. Power electronic packaging is one of the fastest growing segments in the power electronic industry, due to the rapid growth of power integrated circuit (IC) fabrication, especially for applications like portable, consumer, home, computing and automotive electronics. This book also covers how advances in both semiconductor content and power advanced package design have helped cause advances in power device capability in recent years. The author extrapolates the most recent trends in the book's areas of focus to highlight where further improvement in materials and techniques can d...

  10. ZONE package of the Central Valley Hydrologic Model

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This digital dataset defines the model grid, active cells in model layers 2 and 3, and geologic province arrays of the ZONE package used in the transient hydrologic...

  11. Metallization and packaging of compound semiconductor devices at Sandia National Laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Seigal, P.K.; Armendariz, M.G.; Rieger, D.J.; Lear, K.L.; Sullivan, C.T.

    1996-11-01

    Recent advances in compound semiconductor technology utilize a variety of metal thin films fabricated by thermal and electron-beam evaporation, and electroplating. An overview of metal processes used by Sandia`s Compound Semiconductor Research Laboratory is presented. Descriptions of electrical n-type and p-type ohmic contact alloys, interconnect metal, and metal layers specifically included for packaging requirements are addressed. Several illustrations of devices incorporating gold plated air bridges are included. ``Back-end`` processes such as flip-chip under bump metallurgy with fluxless solder reflow and plated solder processes are mentioned as current research areas.

  12. AGING PERFORMANCE OF MODEL 9975 PACKAGE FLUOROELASTOMER O-RINGS

    Energy Technology Data Exchange (ETDEWEB)

    Hoffman, E.; Daugherty, W.; Skidmore, E.; Dunn, K.; Fisher, D.

    2011-05-31

    The influence of temperature and radiation on Viton{reg_sign} GLT and GLT-S fluoroelastomer O-rings is an ongoing research focus at the Savannah River National Laboratory. The O-rings are credited for leaktight containment in the Model 9975 shipping package used for transportation of plutonium-bearing materials. At the Savannah River Site, the Model 9975 packages are being used for interim storage. Primary research efforts have focused on surveillance of O-rings from actual packages, leak testing of seals at bounding aging conditions and the effect of aging temperature on compression stress relaxation behavior, with the goal of service life prediction for long-term storage conditions. Recently, an additional effort to evaluate the effect of aging temperature on the oxidation of the materials has begun. Degradation in the mechanical properties of elastomers is directly related to the oxidation of the polymer. Sensitive measurements of the oxidation rate can be performed in a more timely manner than waiting for a measurable change in mechanical properties, especially at service temperatures. Measuring the oxidation rate therefore provides a means to validate the assumption that the degradation mechanisms(s) do not change from the elevated temperatures used for accelerated aging and the lower service temperatures. Monitoring the amount of oxygen uptake by the material over time at various temperatures can provide increased confidence in lifetime predictions. Preliminary oxygen consumption analysis of a Viton GLT-based fluoroelastomer compound (Parker V0835-75) using an Oxzilla II differential oxygen analyzer in the temperature range of 40-120 C was performed. Early data suggests oxygen consumption rates may level off within the first 100,000 hours (10-12 years) at 40 C and that sharp changes in the degradation mechanism (stress-relaxation) are not expected over the temperature range examined. This is consistent with the known long-term heat aging resistance of

  13. Computational Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory contains a number of commercial off-the-shelf and in-house software packages allowing for both statistical analysis as well as mathematical modeling...

  14. The gRbase package for graphical modelling in R

    DEFF Research Database (Denmark)

    Højsgaard, Søren; Dethlefsen, Claus

    We have developed a package, called , consisting of a number of classes and associated methods to support the analysis of data using graphical models. It is developed for the open source language, R, and is available for several platforms. The package is intended to be widely extendible and flexi...... these building blocks can be combined and integrated with inference engines in the special cases of hierarchical log-linear models (undirected models). gRbase gRbase dynamicGraph...... and flexible so that package developers may implement further types of graphical models using the available methods. contains methods for representing data, specification of models using a formal language, and is linked to , an interactive graphical user interface for manipulating graphs. We show how...

  15. An Overview on R Packages for Structural Equation Modeling

    Directory of Open Access Journals (Sweden)

    Haibin Qiu

    2014-05-01

    Full Text Available The aim of this study is to present overview on R packages for structural equation modeling. Structural equation modeling, a statistical technique for testing and estimating causal relations using an amalgamation of statistical data and qualitative causal hypotheses, allow both confirmatory and exploratory modeling, meaning they are matched to both hypothesis testing and theory development. R project or R language, a free and popular programming language and computer software surroundings for statistical computing and graphics, is popularly used among statisticians for developing statistical computer software and data analysis. The major finding is that it is necessary to build excellent and enough structural equation modeling packages for R users to do research. Numerous packages for structural equation modeling of R project are introduced in this study and most of them are enclosed in the Comprehensive R Archive Network task view Psychometrics.

  16. Structural Equation Modeling Diagnostics Using R Package Semdiag and EQS

    Science.gov (United States)

    Yuan, Ke-Hai; Zhang, Zhiyong

    2012-01-01

    Yuan and Hayashi (2010) introduced 2 scatter plots for model and data diagnostics in structural equation modeling (SEM). However, the generation of the plots requires in-depth understanding of their underlying technical details. This article develops and introduces an R package semdiag for easily drawing the 2 plots. With a model specified in EQS…

  17. Mass Transfer Model for a Breached Waste Package

    Energy Technology Data Exchange (ETDEWEB)

    C. Hsu; J. McClure

    2004-07-26

    The degradation of waste packages, which are used for the disposal of spent nuclear fuel in the repository, can result in configurations that may increase the probability of criticality. A mass transfer model is developed for a breached waste package to account for the entrainment of insoluble particles. In combination with radionuclide decay, soluble advection, and colloidal transport, a complete mass balance of nuclides in the waste package becomes available. The entrainment equations are derived from dimensionless parameters such as drag coefficient and Reynolds number and based on the assumption that insoluble particles are subjected to buoyant force, gravitational force, and drag force only. Particle size distributions are utilized to calculate entrainment concentration along with geochemistry model abstraction to calculate soluble concentration, and colloid model abstraction to calculate colloid concentration and radionuclide sorption. Results are compared with base case geochemistry model, which only considers soluble advection loss.

  18. Mathematical Model and Programming in VBA Excel for Package Calculation

    Directory of Open Access Journals (Sweden)

    João Daniel Reis Lessa

    2016-05-01

    Full Text Available The industrial logistics is a fundamental pillar for the survival of companies in the actual increasingly competitive market. It is not exclusively about controlling the flow of external material between suppliers and the company, but for developing a detailed study of how to plan, control, handle and package those materials as well. Logistics activities must ensure the maximum efficiency in using corporate resources once they do not add value to the final product. The creation of a logistic plan, for each piece of the company’s production, has to adapt the demand parameters, seasonal or not, in the timeline. Thus, the definition of packaging (transportation and consumption must adjust in accordance with the demand, in order to allow the logistic planning to work, constantly, with order of economy batches. The packaging calculation for each part in every demand can become well complicated due to the large amount of parts in the production process. Automating the calculation process for choosing the right package for each piece is an effective method in logistics planning. This article will expose a simple and practical mathematical model for automating the packaging calculation and a logic program, created in Visual Basic language in the Excel software, used for creating graphic designs that show how the packages are being filled.

  19. Linear latent variable models: the lava-package

    DEFF Research Database (Denmark)

    Holst, Klaus Kähler; Budtz-Jørgensen, Esben

    2013-01-01

    An R package for specifying and estimating linear latent variable models is presented. The philosophy of the implementation is to separate the model specification from the actual data, which leads to a dynamic and easy way of modeling complex hierarchical structures. Several advanced features are...... interface covering a broad range of non-linear generalized structural equation models is described. The model and software are demonstrated in data of measurements of the serotonin transporter in the human brain....

  20. Alternative buffer material. Status of the ongoing laboratory investigation of reference materials and test package 1

    Energy Technology Data Exchange (ETDEWEB)

    Svensson, Daniel [Swedish Nuclear Fuel and Waste Management Co., Stockholm (Sweden); Dueck, Ann; Nilsson, Ulf; Olsson, Siv; Sanden, Torbjoern [Clay Technology AB, Lund (Sweden); Lydmark, Sara; Jaegerwall, Sara; Pedersen, Karsten [Microbial Analytics Sweden AB, Moelnlycke (Sweden); Hansen, Staffan [LTH Lund Univ., Lund (Sweden)

    2011-07-15

    Bentonite clay is part of the Swedish KBS-3 design of final repositories for high level radioactive waste. Wyoming bentonite with the commercial name MX-80 (American Colloid Co) has long been the reference for buffer material in the KBS-3 concept. Extending the knowledge base of alternative buffer materials will make it possible to optimize regarding safety, availability and cost. For this reason the field experiment Alternative Buffer Material (ABM) was started at Aespoe Hard Rock Laboratory during 2006. The experiment includes three medium-scale test packages, each consisting of a central steel tube with heaters, and a buffer of compacted clay. Eleven different clays were chosen for the buffers to examine effects of smectite content, interlayer cations and overall iron content. Also bentonite pellets with and without additional quartz are being tested. The buffer in package 1 had been subjected to wetting by formation water and heating for more than two years (at 130 deg C for {approx} 1 year) when it was retrieved and analyzed. The main purposes of the project were to characterise the clays with respect to hydro-mechanical properties, mineralogy and chemical composition and to identify any differences in behaviour or long term stability. The diversity of clays and the heater of steel also make the experiment suitable for studies of iron-bentonite interactions. This report concerns the work accomplished up to now and is not to be treated as any final report of the project.

  1. dMODELS: A software package for modeling volcanic deformation

    Science.gov (United States)

    Battaglia, Maurizio

    2017-04-01

    dMODELS is a software package that includes the most common source models used to interpret deformation measurements near active volcanic centers. The emphasis is on estimating the parameters of analytical models of deformation by inverting data from the Global Positioning System (GPS), Interferometric Synthetic Aperture Radar (InSAR), tiltmeters and strainmeters. Source models include: (a) pressurized spherical, ellipsoidal and sill-like magma chambers in an elastic, homogeneous, flat half-space; (b) pressurized spherical magma chambers with topography corrections; and (c) the solutions for a dislocation (fracture) in an elastic, homogeneous, flat half-space. All of the equations have been extended to include deformation and strain within the Earth's crust (as opposed to only at the Earth's surface) and verified against finite element models. Although actual volcanic sources are not embedded cavities of simple shape, we assume that these models may reproduce the stress field created by the actual magma intrusion or hydrothermal fluid injection. The dMODELS software employs a nonlinear inversion algorithm to determine the best-fit parameters for the deformation source by searching for the minimum of the cost function χv2 (chi square per degrees of freedom). The non-linear inversion algorithm is a combination of local optimization (interior-point method) and random search. This approach is more efficient for hyper-parameter optimization than trials on a grid. The software has been developed using MATLAB, but compiled versions that can be run using the free MATLAB Compiler Runtime (MCR) module are available for Windows 64-bit operating systems. The MATLAB scripts and compiled files are open source and intended for teaching and research. The software package includes both functions for forward modeling and scripts for data inversion. A software demonstration will be available during the meeting. You are welcome to contact the author at mbattaglia@usgs.gov for

  2. A Kinetic Model for Predicting the Relative Humidity in Modified Atmosphere Packaging and Its Application in Lentinula edodes Packages

    Directory of Open Access Journals (Sweden)

    Li-xin Lu

    2013-01-01

    Full Text Available Adjusting and controlling the relative humidity (RH inside package is crucial for ensuring the quality of modified atmosphere packaging (MAP of fresh produce. In this paper, an improved kinetic model for predicting the RH in MAP was developed. The model was based on heat exchange and gases mass transport phenomena across the package, gases heat convection inside the package, and mass and heat balances accounting for the respiration and transpiration behavior of fresh produce. Then the model was applied to predict the RH in MAP of fresh Lentinula edodes (one kind of Chinese mushroom. The model equations were solved numerically using Adams-Moulton method to predict the RH in model packages. In general, the model predictions agreed well with the experimental data, except that the model predictions were slightly high in the initial period. The effect of the initial gas composition on the RH in packages was notable. In MAP of lower oxygen and higher carbon dioxide concentrations, the ascending rate of the RH was reduced, and the RH inside packages was saturated slowly during storage. The influence of the initial gas composition on the temperature inside package was not much notable.

  3. MODEL 9975 SHIPPING PACKAGE FABRICATION PROBLEMS AND SOLUTIONS

    Energy Technology Data Exchange (ETDEWEB)

    May, C; Allen Smith, A

    2008-05-07

    The Model 9975 Shipping Package is the latest in a series (9965, 9968, etc.) of radioactive material shipping packages that have been the mainstay for shipping radioactive materials for several years. The double containment vessels are relatively simple designs using pipe and pipe cap in conjunction with the Chalfont closure to provide a leak-tight vessel. The fabrication appears simple in nature, but the history of fabrication tells us there are pitfalls in the different fabrication methods and sequences. This paper will review the problems that have arisen during fabrication and precautions that should be taken to meet specifications and tolerances. The problems and precautions can also be applied to the Models 9977 and 9978 Shipping Packages.

  4. MODEL 9975 LIFE EXTENSION TEST PACKAGE 3 - INTERIM REPORT - JANUARY 2017

    Energy Technology Data Exchange (ETDEWEB)

    Daugherty, W. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-01-31

    Life extension package LE3 (9975-03203) has been instrumented and subjected to an elevated temperature environment for approximately 8 years. During this time, the cane fiberboard has been maintained at a maximum temperature of ~160 - 165 °F, which was established by a combination of internal (19 watts) and external heat sources. Several tests and parameters were used to characterize the package components. Results from these tests generally indicate agreement between this full-scale shipping package and small-scale laboratory tests on fiberboard samples, including the degradation models based on the laboratory tests. These areas of agreement include the rate of change of fiberboard weight, dimensions and density, and change in fiberboard thermal conductivity. Corrosion of the lead shield occurred at a high rate during the first several weeks of aging, but dropped significantly after most of the moisture in the fiberboard migrated away from the lead shield. Dimensional measurements of the lead shield indicate that no significant creep deformation has occurred. This is consistent with literature data that predict a very small creep deformation for the time at temperature experienced by this package. The SCV O-rings were verified to remain leak-tight after ~5 years aging at an average temperature of ~170 °F. This package provides an example of the extent to which moisture within a typical fiberboard assembly can redistribute in the presence of a temperature gradient such as might be created by a 19 watt internal heat load. The majority of water within the fiberboard migrated to the bottom layers of fiberboard, with approximately 2 kg of water (2 liters) eventually escaping from the package. Two conditions have developed that are not consistent with package certification requirements. The axial gap at the top of the package increased to a maximum value of 1.549 inches, exceeding the 1 inch criterion. In addition, staining and/or corrosion have formed in a few spots

  5. Laboratory Tests of Chameleon Models

    CERN Document Server

    Brax, Philippe; Davis, Anne-Christine; Shaw, Douglas

    2009-01-01

    We present a cursory overview of chameleon models of dark energy and their laboratory tests with an emphasis on optical and Casimir experiments. Optical experiments measuring the ellipticity of an initially polarised laser beam are sensitive to the coupling of chameleons to photons. The next generation of Casimir experiments may be able to unravel the nature of the scalar force mediated by the chameleon between parallel plates.

  6. VR Lab ISS Graphics Models Data Package

    Science.gov (United States)

    Paddock, Eddie; Homan, Dave; Bell, Brad; Miralles, Evely; Hoblit, Jeff

    2016-01-01

    All the ISS models are saved in AC3D model format which is a text based format that can be loaded into blender and exported to other formats from there including FBX. The models are saved in two different levels of detail, one being labeled "LOWRES" and the other labeled "HIRES". There are two ".str" files (HIRES _ scene _ load.str and LOWRES _ scene _ load.str) that give the hierarchical relationship of the different nodes and the models associated with each node for both the "HIRES" and "LOWRES" model sets. All the images used for texturing are stored in Windows ".bmp" format for easy importing.

  7. High power electronics package: from modeling to implementation

    NARCIS (Netherlands)

    Yuan, C.A.; Kregting, R.; Ye, H.; Driel, W. van; Gielen, A.W.J.; Zhang, G.Q.

    2011-01-01

    Power electronics, such as high power RF components and high power LEDs, requires the combination of robust and reliable package structures, materials, and processes to guarantee their functional performance and lifetime. We started with the thermal and thermal-mechanical modeling of such component

  8. Linear latent variable models: the lava-package

    DEFF Research Database (Denmark)

    Holst, Klaus Kähler; Budtz-Jørgensen, Esben

    2013-01-01

    An R package for specifying and estimating linear latent variable models is presented. The philosophy of the implementation is to separate the model specification from the actual data, which leads to a dynamic and easy way of modeling complex hierarchical structures. Several advanced features...... are implemented including robust standard errors for clustered correlated data, multigroup analyses, non-linear parameter constraints, inference with incomplete data, maximum likelihood estimation with censored and binary observations, and instrumental variable estimators. In addition an extensive simulation...

  9. The TriLab, a Novel ICT Based Triple Access Mode Laboratory Education Model

    Science.gov (United States)

    Abdulwahed, Mahmoud; Nagy, Zoltan K.

    2011-01-01

    This paper introduces a novel model of laboratory education, namely the TriLab. The model is based on recent advances in ICT and implements a three access modes to the laboratory experience (virtual, hands-on and remote) in one software package. A review of the three modes is provided with highlights of advantages and disadvantages of each mode.…

  10. The R Package bgmm : Mixture Modeling with Uncertain Knowledge

    Directory of Open Access Journals (Sweden)

    Przemys law Biecek

    2012-04-01

    Full Text Available Classical supervised learning enjoys the luxury of accessing the true known labels for the observations in a modeled dataset. Real life, however, poses an abundance of problems, where the labels are only partially defined, i.e., are uncertain and given only for a subsetof observations. Such partial labels can occur regardless of the knowledge source. For example, an experimental assessment of labels may have limited capacity and is prone to measurement errors. Also expert knowledge is often restricted to a specialized area and is thus unlikely to provide trustworthy labels for all observations in the dataset. Partially supervised mixture modeling is able to process such sparse and imprecise input. Here, we present an R package calledbgmm, which implements two partially supervised mixture modeling methods: soft-label and belief-based modeling. For completeness, we equipped the package also with the functionality of unsupervised, semi- and fully supervised mixture modeling. On real data we present the usage of bgmm for basic model-fitting in all modeling variants. The package can be applied also to selection of the best-fitting from a set of models with different component numbers or constraints on their structures. This functionality is presented on an artificial dataset, which can be simulated in bgmm from a distribution defined by a given model.

  11. LABORATORY MODELS FOR SCREENING ANALGESICS

    Directory of Open Access Journals (Sweden)

    Parle Milind

    2013-01-01

    Full Text Available Pain is a complex unpleasant phenomenon composed of sensory experiences that include time, space, intensity, emotion, cognition and motivation. Analgesics are the agents, which selectively relieve pain by acting in the CNS or by peripheral pain mechanisms without significantly altering consciousness. Analgesics may be narcotic or non-narcotic. The study of pain in animals raises ethical, philosophical and technical problems. Philosophically, there is a problem that pain cannot be monitored directly in animals but can only be measured by examining their responses to nociceptive stimuli. The observed reactions are almost always motor responses ranging from spinal reflexes to complex behavior. The animal models employed for screening of analgesic agents, include Pain-state models based on the use of thermal stimuli, mechanical stimuli, electrical stimuli and chemical stimuli. The neuronal basis of most of the above laboratory models is poorly understood, however their application is profitable in predicting analgesic activity of newly discovered substances.

  12. Documentation pckage for the RFID temperature monitoring system (Of Model 9977 packages at NTS).

    Energy Technology Data Exchange (ETDEWEB)

    Chen, K.; Tsai, H.; Decision and Information Sciences

    2009-02-20

    The technical basis for extending the Model 9977 shipping package periodic maintenance beyond the one-year interval to a maximum of five years is based on the performance of the O-ring seals and the environmental conditions. The DOE Packaging Certification Program (PCP) has tasked Argonne National Laboratory to develop a Radio-Frequency Identification (RFID) temperature monitoring system for use by the facility personnel at DAF/NTS. The RFID temperature monitoring system, depicted in the figure below, consists of the Mk-1 RFId tags, a reader, and a control computer mounted on a mobile platform that can operate as a stand-alone system, or it can be connected to the local IT network. As part of the Conditions of Approval of the CoC, the user must complete the prescribed training to become qualified and be certified for operation of the RFID temperature monitoring system. The training course will be administered by Argonne National Laboratory on behalf of the Headquarters Certifying Official. This is a complete documentation package for the RFID temperature monitoring system of the Model 9977 packagings at NTS. The documentation package will be used for training and certification. The table of contents are: Acceptance Testing Procedure of MK-1 RFID Tags for DOE/EM Nuclear Materials Management Applications; Acceptance Testing Result of MK-1 RFID Tags for DOE/EM Nuclear Materials Management Applications; Performance Test of the Single Bolt Seal Sensor for the Model 9977 Packaging; Calibration of Built-in Thermistors in RFID Tags for Nevada Test Site; Results of Calibration of Built-in Thermistors in RFID Tags; Results of Thermal Calibration of Second Batch of MK-I RFID Tags; Procedure for Installing and Removing MK-1 RFID Tag on Model 9977 Drum; User Guide for RFID Reader and Software for Temperature Monitoring of Model 9977 Drums at NTS; Software Quality Assurance Plan (SQAP) for the ARG-US System; Quality Category for the RFID Temperature Monitoring System; The

  13. A Common Platform for Graphical Models in R: The gRbase Package

    Directory of Open Access Journals (Sweden)

    Claus Dethlefsen

    2005-12-01

    Full Text Available The gRbase package is intended to set the framework for computer packages for data analysis using graphical models. The gRbase package is developed for the open source language, R, and is available for several platforms. The package is intended to be widely extendible and flexible so that package developers may implement further types of graphical models using the available methods. The gRbase package consists of a set of S version 3 classes and associated methods for representing data and models. The package is linked to the dynamicGraph package (Badsberg 2005, an interactive graphical user interface for manipulating graphs.In this paper, we show how these building blocks can be combined and integrated with inference engines in the special cases of hierarchical loglinear models. We also illustrate how to extend the package to deal with other types of graphical models, in this case the graphical Gaussian models.

  14. Mixed Frequency Data Sampling Regression Models: The R Package midasr

    Directory of Open Access Journals (Sweden)

    Eric Ghysels

    2016-08-01

    Full Text Available When modeling economic relationships it is increasingly common to encounter data sampled at different frequencies. We introduce the R package midasr which enables estimating regression models with variables sampled at different frequencies within a MIDAS regression framework put forward in work by Ghysels, Santa-Clara, and Valkanov (2002. In this article we define a general autoregressive MIDAS regression model with multiple variables of different frequencies and show how it can be specified using the familiar R formula interface and estimated using various optimization methods chosen by the researcher. We discuss how to check the validity of the estimated model both in terms of numerical convergence and statistical adequacy of a chosen regression specification, how to perform model selection based on a information criterion, how to assess forecasting accuracy of the MIDAS regression model and how to obtain a forecast aggregation of different MIDAS regression models. We illustrate the capabilities of the package with a simulated MIDAS regression model and give two empirical examples of application of MIDAS regression.

  15. PKgraph: an R package for graphically diagnosing population pharmacokinetic models.

    Science.gov (United States)

    Sun, Xiaoyong; Wu, Kai; Cook, Dianne

    2011-12-01

    Population pharmacokinetic (PopPK) modeling has become increasing important in drug development because it handles unbalanced design, sparse data and the study of individual variation. However, the increased complexity of the model makes it more of a challenge to diagnose the fit. Graphics can play an important and unique role in PopPK model diagnostics. The software described in this paper, PKgraph, provides a graphical user interface for PopPK model diagnosis. It also provides an integrated and comprehensive platform for the analysis of pharmacokinetic data including exploratory data analysis, goodness of model fit, model validation and model comparison. Results from a variety of modeling fitting software, including NONMEM, Monolix, SAS and R, can be used. PKgraph is programmed in R, and uses the R packages lattice, ggplot2 for static graphics, and rggobi for interactive graphics.

  16. Package models and the information crisis of prebiotic evolution.

    Science.gov (United States)

    Silvestre, Daniel A M M; Fontanari, José F

    2008-05-21

    The coexistence between different types of templates has been the choice solution to the information crisis of prebiotic evolution, triggered by the finding that a single RNA-like template cannot carry enough information to code for any useful replicase. In principle, confining d distinct templates of length L in a package or protocell, whose survival depends on the coexistence of the templates it holds in, could resolve this crisis provided that d is made sufficiently large. Here we review the prototypical package model of Niesert et al. [1981. Origin of life between Scylla and Charybdis. J. Mol. Evol. 17, 348-353] which guarantees the greatest possible region of viability of the protocell population, and show that this model, and hence the entire package approach, does not resolve the information crisis. In particular, we show that the total information stored in a viable protocell (Ld) tends to a constant value that depends only on the spontaneous error rate per nucleotide of the template replication mechanism. As a result, an increase of d must be followed by a decrease of L, so that the net information gain is null.

  17. Deconvolution Estimation in Measurement Error Models: The R Package decon

    Directory of Open Access Journals (Sweden)

    Xiao-Feng Wang

    2011-03-01

    Full Text Available Data from many scientific areas often come with measurement error. Density or distribution function estimation from contaminated data and nonparametric regression with errors in variables are two important topics in measurement error models. In this paper, we present a new software package decon for R, which contains a collection of functions that use the deconvolution kernel methods to deal with the measurement error problems. The functions allow the errors to be either homoscedastic or heteroscedastic. To make the deconvolution estimators computationally more efficient in R, we adapt the fast Fourier transform algorithm for density estimation with error-free data to the deconvolution kernel estimation. We discuss the practical selection of the smoothing parameter in deconvolution methods and illustrate the use of the package through both simulated and real examples.

  18. COMPUTATIONAL MODELLING OF BUFFETING EFFECTS USING OPENFOAM SOFTWARE PACKAGE

    Directory of Open Access Journals (Sweden)

    V. T. Kalugin

    2015-01-01

    Full Text Available In this paper, the preliminary results of computational modeling of an aircraft with the airbrake deployed are presented. The calculations were performed with OpenFOAM software package. The results outlined are a part of a research project to optimise aircraft performance using a perforated airbrake. Within this stage of the project OpenFOAM software package with hybrid RANS-LES approach was tested in respect to a given configuration of the aircraft, airbrake and then has been compared with the test data. For the worst case the amplitude of the peak force acting on the tail fin can be up to 6 times higher than the average value without airbrake deployed. To reduce unsteady loads acting on the tailfin, perforation of the airbrake was proposed.

  19. RECERTIFICATION OF THE MODEL 9977 RADIOACTIVE MATERIAL PACKAGING

    Energy Technology Data Exchange (ETDEWEB)

    Abramczyk, G.; Bellamy, S.; Loftin, B.; Nathan, S.

    2013-06-05

    The Model 9977 Packaging was initially issued a Certificate of Compliance (CoC) by the Department of Energy’s Office of Environmental Management (DOE-EM) for the transportation of radioactive material (RAM) in the Fall of 2007. This first CoC was for a single radioactive material and two packing configurations. In the five years since that time, seven Addendums have been written to the Safety Analysis Report for Packaging (SARP) and five Letter Amendments have been written that have authorized either new RAM contents or packing configurations, or both. This paper will discuss the process of updating the 9977 SARP to include all the contents and configurations, including the addition of a new content, and its submittal for recertification.

  20. dglars: An R Package to Estimate Sparse Generalized Linear Models

    Directory of Open Access Journals (Sweden)

    Luigi Augugliaro

    2014-09-01

    Full Text Available dglars is a publicly available R package that implements the method proposed in Augugliaro, Mineo, and Wit (2013, developed to study the sparse structure of a generalized linear model. This method, called dgLARS, is based on a differential geometrical extension of the least angle regression method proposed in Efron, Hastie, Johnstone, and Tibshirani (2004. The core of the dglars package consists of two algorithms implemented in Fortran 90 to efficiently compute the solution curve: a predictor-corrector algorithm, proposed in Augugliaro et al. (2013, and a cyclic coordinate descent algorithm, proposed in Augugliaro, Mineo, and Wit (2012. The latter algorithm, as shown here, is significantly faster than the predictor-corrector algorithm. For comparison purposes, we have implemented both algorithms.

  1. Fitting Additive Binomial Regression Models with the R Package blm

    Directory of Open Access Journals (Sweden)

    Stephanie Kovalchik

    2013-09-01

    Full Text Available The R package blm provides functions for fitting a family of additive regression models to binary data. The included models are the binomial linear model, in which all covariates have additive effects, and the linear-expit (lexpit model, which allows some covariates to have additive effects and other covariates to have logisitc effects. Additive binomial regression is a model of event probability, and the coefficients of linear terms estimate covariate-adjusted risk differences. Thus, in contrast to logistic regression, additive binomial regression puts focus on absolute risk and risk differences. In this paper, we give an overview of the methodology we have developed to fit the binomial linear and lexpit models to binary outcomes from cohort and population-based case-control studies. We illustrate the blm packages methods for additive model estimation, diagnostics, and inference with risk association analyses of a bladder cancer nested case-control study in the NIH-AARP Diet and Health Study.

  2. scoringRules - A software package for probabilistic model evaluation

    Science.gov (United States)

    Lerch, Sebastian; Jordan, Alexander; Krüger, Fabian

    2016-04-01

    Models in the geosciences are generally surrounded by uncertainty, and being able to quantify this uncertainty is key to good decision making. Accordingly, probabilistic forecasts in the form of predictive distributions have become popular over the last decades. With the proliferation of probabilistic models arises the need for decision theoretically principled tools to evaluate the appropriateness of models and forecasts in a generalized way. Various scoring rules have been developed over the past decades to address this demand. Proper scoring rules are functions S(F,y) which evaluate the accuracy of a forecast distribution F , given that an outcome y was observed. As such, they allow to compare alternative models, a crucial ability given the variety of theories, data sources and statistical specifications that is available in many situations. This poster presents the software package scoringRules for the statistical programming language R, which contains functions to compute popular scoring rules such as the continuous ranked probability score for a variety of distributions F that come up in applied work. Two main classes are parametric distributions like normal, t, or gamma distributions, and distributions that are not known analytically, but are indirectly described through a sample of simulation draws. For example, Bayesian forecasts produced via Markov Chain Monte Carlo take this form. Thereby, the scoringRules package provides a framework for generalized model evaluation that both includes Bayesian as well as classical parametric models. The scoringRules package aims to be a convenient dictionary-like reference for computing scoring rules. We offer state of the art implementations of several known (but not routinely applied) formulas, and implement closed-form expressions that were previously unavailable. Whenever more than one implementation variant exists, we offer statistically principled default choices.

  3. gems: An R Package for Simulating from Disease Progression Models

    Directory of Open Access Journals (Sweden)

    Nello Blaser

    2015-03-01

    Full Text Available Mathematical models of disease progression predict disease outcomes and are useful epidemiological tools for planners and evaluators of health interventions. The R package gems is a tool that simulates disease progression in patients and predicts the effect of different interventions on patient outcome. Disease progression is represented by a series of events (e.g., diagnosis, treatment and death, displayed in a directed acyclic graph. The vertices correspond to disease states and the directed edges represent events. The package gems allows simulations based on a generalized multistate model that can be described by a directed acyclic graph with continuous transition-specific hazard functions. The user can specify an arbitrary hazard function and its parameters. The model includes parameter uncertainty, does not need to be a Markov model, and may take the history of previous events into account. Applications are not limited to the medical field and extend to other areas where multistate simulation is of interest. We provide a technical explanation of the multistate models used by gems, explain the functions of gems and their arguments, and show a sample application.

  4. A Thermodynamic Model for Genome Packaging in Hepatitis B Virus.

    Science.gov (United States)

    Kim, Jehoon; Wu, Jianzhong

    2015-10-20

    Understanding the fundamentals of genome packaging in viral capsids is important for finding effective antiviral strategies and for utilizing benign viral particles for gene therapy. While the structure of encapsidated genomic materials has been routinely characterized with experimental techniques such as cryo-electron microscopy and x-ray diffraction, much less is known about the molecular driving forces underlying genome assembly in an intracellular environment and its in vivo interactions with the capsid proteins. Here we study the thermodynamic basis of the pregenomic RNA encapsidation in human Hepatitis B virus in vivo using a coarse-grained molecular model that captures the essential components of nonspecific intermolecular interactions. The thermodynamic model is used to examine how the electrostatic interaction between the packaged RNA and the highly charged C-terminal domains (CTD) of capsid proteins regulate the nucleocapsid formation. The theoretical model predicts optimal RNA content in Hepatitis B virus nucleocapsids with different CTD lengths in good agreement with mutagenesis measurements, confirming the predominant role of electrostatic interactions and molecular excluded-volume effects in genome packaging. We find that the amount of encapsidated RNA is not linearly correlated with the net charge of CTD tails as suggested by earlier theoretical studies. Our thermodynamic analysis of the nucleocapsid structure and stability indicates that ∼10% of the CTD residues are free from complexation with RNA, resulting in partially exposed CTD tails. The thermodynamic model also predicts the free energy of complex formation between macromolecules, which corroborates experimental results for the impact of CTD truncation on the nucleocapsid stability.

  5. DYNSTALL: Subroutine package with a dynamic stall model

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerck, Anders [Aeronautical Research Inst. of Sweden, Bromma (Sweden)

    2001-03-01

    A subroutine package, called DYNSTALL, for the calculation of 2D unsteady airfoil aerodynamics is described. The subroutines are written in FORTRAN. DYNSTALL is basically an implementation of the Beddoes-Leishman dynamic stall model. This model is a semi-empirical model for dynamic stall. It includes, however, also models for attached flow unsteady aerodynamics. It is complete in the sense that it treats attached flow as well as separated flow. Semi-empirical means that the model relies on empirically determined constants. Semi because the constants are constants in equations with some physical interpretation. It requires the input of 2D airfoil aerodynamic data via tables as function of angle of attack. The method is intended for use in an aeroelastic code with the aerodynamics solved by blade/element method. DYNSTALL was written to work for any 2D angles of attack relative to the airfoil, e.g. flow from the rear of an airfoil.

  6. SPOTting Model Parameters Using a Ready-Made Python Package.

    Science.gov (United States)

    Houska, Tobias; Kraft, Philipp; Chamorro-Chavez, Alejandro; Breuer, Lutz

    2015-01-01

    The choice for specific parameter estimation methods is often more dependent on its availability than its performance. We developed SPOTPY (Statistical Parameter Optimization Tool), an open source python package containing a comprehensive set of methods typically used to calibrate, analyze and optimize parameters for a wide range of ecological models. SPOTPY currently contains eight widely used algorithms, 11 objective functions, and can sample from eight parameter distributions. SPOTPY has a model-independent structure and can be run in parallel from the workstation to large computation clusters using the Message Passing Interface (MPI). We tested SPOTPY in five different case studies to parameterize the Rosenbrock, Griewank and Ackley functions, a one-dimensional physically based soil moisture routine, where we searched for parameters of the van Genuchten-Mualem function and a calibration of a biogeochemistry model with different objective functions. The case studies reveal that the implemented SPOTPY methods can be used for any model with just a minimal amount of code for maximal power of parameter optimization. They further show the benefit of having one package at hand that includes number of well performing parameter search methods, since not every case study can be solved sufficiently with every algorithm or every objective function.

  7. SPOTting Model Parameters Using a Ready-Made Python Package.

    Directory of Open Access Journals (Sweden)

    Tobias Houska

    Full Text Available The choice for specific parameter estimation methods is often more dependent on its availability than its performance. We developed SPOTPY (Statistical Parameter Optimization Tool, an open source python package containing a comprehensive set of methods typically used to calibrate, analyze and optimize parameters for a wide range of ecological models. SPOTPY currently contains eight widely used algorithms, 11 objective functions, and can sample from eight parameter distributions. SPOTPY has a model-independent structure and can be run in parallel from the workstation to large computation clusters using the Message Passing Interface (MPI. We tested SPOTPY in five different case studies to parameterize the Rosenbrock, Griewank and Ackley functions, a one-dimensional physically based soil moisture routine, where we searched for parameters of the van Genuchten-Mualem function and a calibration of a biogeochemistry model with different objective functions. The case studies reveal that the implemented SPOTPY methods can be used for any model with just a minimal amount of code for maximal power of parameter optimization. They further show the benefit of having one package at hand that includes number of well performing parameter search methods, since not every case study can be solved sufficiently with every algorithm or every objective function.

  8. Geoacoustic Physical Model Fabrication Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Fabricates three-dimensional rough surfaces (e.g., fractals, ripples) out of materials such as PVC or wax to simulate the roughness properties associated...

  9. VAR, SVAR and SVEC Models: Implementation Within R Package vars

    Directory of Open Access Journals (Sweden)

    Bernhard Pfaff

    2008-02-01

    Full Text Available The structure of the package vars and its implementation of vector autoregressive, structural vector autoregressive and structural vector error correction models are explained in this paper. In addition to the three cornerstone functions VAR(, SVAR( and SVEC( for estimating such models, functions for diagnostic testing, estimation of a restricted models, prediction, causality analysis, impulse response analysis and forecast error variance decomposition are provided too. It is further possible to convert vector error correction models into their level VAR representation. The different methods and functions are elucidated by employing a macroeconomic data set for Canada. However, the focus in this writing is on the implementation part rather than the usage of the tools at hand.

  10. MNP: R Package for Fitting the Multinomial Probit Model

    Directory of Open Access Journals (Sweden)

    Kosuke Imai

    2005-05-01

    Full Text Available MNP is a publicly available R package that fits the Bayesian multinomial probit model via Markov chain Monte Carlo. The multinomial probit model is often used to analyze the discrete choices made by individuals recorded in survey data. Examples where the multinomial probit model may be useful include the analysis of product choice by consumers in market research and the analysis of candidate or party choice by voters in electoral studies. The MNP software can also fit the model with different choice sets for each individual, and complete or partial individual choice orderings of the available alternatives from the choice set. The estimation is based on the efficient marginal data augmentation algorithm that is developed by Imai and van Dyk (2005.

  11. Continuous Time Structural Equation Modeling with R Package ctsem

    Directory of Open Access Journals (Sweden)

    Charles C. Driver

    2017-04-01

    Full Text Available We introduce ctsem, an R package for continuous time structural equation modeling of panel (N > 1 and time series (N = 1 data, using full information maximum likelihood. Most dynamic models (e.g., cross-lagged panel models in the social and behavioural sciences are discrete time models. An assumption of discrete time models is that time intervals between measurements are equal, and that all subjects were assessed at the same intervals. Violations of this assumption are often ignored due to the difficulty of accounting for varying time intervals, therefore parameter estimates can be biased and the time course of effects becomes ambiguous. By using stochastic differential equations to estimate an underlying continuous process, continuous time models allow for any pattern of measurement occasions. By interfacing to OpenMx, ctsem combines the flexible specification of structural equation models with the enhanced data gathering opportunities and improved estimation of continuous time models. ctsem can estimate relationships over time for multiple latent processes, measured by multiple noisy indicators with varying time intervals between observations. Within and between effects are estimated simultaneously by modeling both observed covariates and unobserved heterogeneity. Exogenous shocks with different shapes, group differences, higher order diffusion effects and oscillating processes can all be simply modeled. We first introduce and define continuous time models, then show how to specify and estimate a range of continuous time models using ctsem.

  12. Alloy Design Workbench-Surface Modeling Package Developed

    Science.gov (United States)

    Abel, Phillip B.; Noebe, Ronald D.; Bozzolo, Guillermo H.; Good, Brian S.; Daugherty, Elaine S.

    2003-01-01

    NASA Glenn Research Center's Computational Materials Group has integrated a graphical user interface with in-house-developed surface modeling capabilities, with the goal of using computationally efficient atomistic simulations to aid the development of advanced aerospace materials, through the modeling of alloy surfaces, surface alloys, and segregation. The software is also ideal for modeling nanomaterials, since surface and interfacial effects can dominate material behavior and properties at this level. Through the combination of an accurate atomistic surface modeling methodology and an efficient computational engine, it is now possible to directly model these types of surface phenomenon and metallic nanostructures without a supercomputer. Fulfilling a High Operating Temperature Propulsion Components (HOTPC) project level-I milestone, a graphical user interface was created for a suite of quantum approximate atomistic materials modeling Fortran programs developed at Glenn. The resulting "Alloy Design Workbench-Surface Modeling Package" (ADW-SMP) is the combination of proven quantum approximate Bozzolo-Ferrante-Smith (BFS) algorithms (refs. 1 and 2) with a productivity-enhancing graphical front end. Written in the portable, platform independent Java programming language, the graphical user interface calls on extensively tested Fortran programs running in the background for the detailed computational tasks. Designed to run on desktop computers, the package has been deployed on PC, Mac, and SGI computer systems. The graphical user interface integrates two modes of computational materials exploration. One mode uses Monte Carlo simulations to determine lowest energy equilibrium configurations. The second approach is an interactive "what if" comparison of atomic configuration energies, designed to provide real-time insight into the underlying drivers of alloying processes.

  13. SPOTting model parameters using a ready-made Python package

    Science.gov (United States)

    Houska, Tobias; Kraft, Philipp; Breuer, Lutz

    2015-04-01

    The selection and parameterization of reliable process descriptions in ecological modelling is driven by several uncertainties. The procedure is highly dependent on various criteria, like the used algorithm, the likelihood function selected and the definition of the prior parameter distributions. A wide variety of tools have been developed in the past decades to optimize parameters. Some of the tools are closed source. Due to this, the choice for a specific parameter estimation method is sometimes more dependent on its availability than the performance. A toolbox with a large set of methods can support users in deciding about the most suitable method. Further, it enables to test and compare different methods. We developed the SPOT (Statistical Parameter Optimization Tool), an open source python package containing a comprehensive set of modules, to analyze and optimize parameters of (environmental) models. SPOT comes along with a selected set of algorithms for parameter optimization and uncertainty analyses (Monte Carlo, MC; Latin Hypercube Sampling, LHS; Maximum Likelihood, MLE; Markov Chain Monte Carlo, MCMC; Scuffled Complex Evolution, SCE-UA; Differential Evolution Markov Chain, DE-MCZ), together with several likelihood functions (Bias, (log-) Nash-Sutcliff model efficiency, Correlation Coefficient, Coefficient of Determination, Covariance, (Decomposed-, Relative-, Root-) Mean Squared Error, Mean Absolute Error, Agreement Index) and prior distributions (Binomial, Chi-Square, Dirichlet, Exponential, Laplace, (log-, multivariate-) Normal, Pareto, Poisson, Cauchy, Uniform, Weibull) to sample from. The model-independent structure makes it suitable to analyze a wide range of applications. We apply all algorithms of the SPOT package in three different case studies. Firstly, we investigate the response of the Rosenbrock function, where the MLE algorithm shows its strengths. Secondly, we study the Griewank function, which has a challenging response surface for

  14. Use of advanced modeling techniques to optimize thermal packaging designs.

    Science.gov (United States)

    Formato, Richard M; Potami, Raffaele; Ahmed, Iftekhar

    2010-01-01

    Through a detailed case study the authors demonstrate, for the first time, the capability of using advanced modeling techniques to correctly simulate the transient temperature response of a convective flow-based thermal shipper design. The objective of this case study was to demonstrate that simulation could be utilized to design a 2-inch-wall polyurethane (PUR) shipper to hold its product box temperature between 2 and 8 °C over the prescribed 96-h summer profile (product box is the portion of the shipper that is occupied by the payload). Results obtained from numerical simulation are in excellent agreement with empirical chamber data (within ±1 °C at all times), and geometrical locations of simulation maximum and minimum temperature match well with the corresponding chamber temperature measurements. Furthermore, a control simulation test case was run (results taken from identical product box locations) to compare the coupled conduction-convection model with a conduction-only model, which to date has been the state-of-the-art method. For the conduction-only simulation, all fluid elements were replaced with "solid" elements of identical size and assigned thermal properties of air. While results from the coupled thermal/fluid model closely correlated with the empirical data (±1 °C), the conduction-only model was unable to correctly capture the payload temperature trends, showing a sizeable error compared to empirical values (ΔT > 6 °C). A modeling technique capable of correctly capturing the thermal behavior of passively refrigerated shippers can be used to quickly evaluate and optimize new packaging designs. Such a capability provides a means to reduce the cost and required design time of shippers while simultaneously improving their performance. Another advantage comes from using thermal modeling (assuming a validated model is available) to predict the temperature distribution in a shipper that is exposed to ambient temperatures which were not bracketed

  15. glmulti: An R Package for Easy Automated Model Selection with (Generalized Linear Models

    Directory of Open Access Journals (Sweden)

    Vincent Calcagno

    2010-10-01

    Full Text Available We introduce glmulti, an R package for automated model selection and multi-model inference with glm and related functions. From a list of explanatory variables, the provided function glmulti builds all possible unique models involving these variables and, optionally, their pairwise interactions. Restrictions can be specified for candidate models, by excluding specific terms, enforcing marginality, or controlling model complexity. Models are fitted with standard R functions like glm. The n best models and their support (e.g., (QAIC, (QAICc, or BIC are returned, allowing model selection and multi-model inference through standard R functions. The package is optimized for large candidate sets by avoiding memory limitation, facilitating parallelization and providing, in addition to exhaustive screening, a compiled genetic algorithm method. This article briefly presents the statistical framework and introduces the package, with applications to simulated and real data.

  16. PtProcess: An R Package for Modelling Marked Point Processes Indexed by Time

    Directory of Open Access Journals (Sweden)

    David Harte

    2010-10-01

    Full Text Available This paper describes the package PtProcess which uses the R statistical language. The package provides a unified approach to fitting and simulating a wide variety of temporal point process or temporal marked point process models. The models are specified by an intensity function which is conditional on the history of the process. The user needs to provide routines for calculating the conditional intensity function. Then the package enables one to carry out maximum likelihood fitting, goodness of fit testing, simulation and comparison of models. The package includes the routines for the conditional intensity functions for a variety of standard point process models. The package is intended to simplify the fitting of point process models indexed by time in much the same way as generalized linear model programs have simplified the fitting of various linear models. The primary examples used in this paper are earthquake sequences but the package is intended to have a much wider applicability.

  17. CSR behavior and aging model for the Viton© Fluorelastomer O-rings in the 9975 shipping package

    Energy Technology Data Exchange (ETDEWEB)

    Mcwilliams, A. J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Daugherty, W. L. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Skidmore, T. E. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-12-01

    The 9975 Type B shipping package is used within the DOE complex for shipping special nuclear materials. This package is re-certified annually in accordance with Safety Analysis Report for Packaging (SARP) requirements. The package is also used at the Savannah River Site as part of the long-term storage configuration of special nuclear materials. As such, the packages do not undergo annual recertification during storage, with uncertainty as to how long some of the package components will meet their functional requirements in the storage environment. The packages are currently approved for up to 15 years storage, and work continues to provide a technical basis to extend that period. This report describes efforts by the Savannah River National Laboratory (SRNL) to extend the service life estimate of Viton® GLT and GLT-S fluoroelastomer O-rings used in the 9975 shipping package. O-rings of both GLT and GLT-S compositions are undergoing accelerated aging at elevated temperature, and are periodically tested for compression stress relaxation (CSR) behavior. The CSR behavior of O-rings was evaluated at temperatures from 175 to 400 °F. These collective data were used to develop predictive models for extrapolation of CSR behavior to relevant service temperatures (< 156 °F). The predictive model developed from the CSR data conservatively indicates a service life of approximately 37 years for Viton GLT O-rings at the maximum effective service temperature of 156 °F. The estimated service life for Viton GLT-S O-rings is significantly longer.

  18. LABORATORY MODEL OF CHRONIC STAPHYLOCOCCAL TONSILLITIS

    Directory of Open Access Journals (Sweden)

    Shkodovska NYu

    2013-03-01

    Full Text Available Investigation and development of new preparations for chronic tonsillitis (CT treatment and prevention requires application of appropriate laboratory model. For the development of CT laboratory model chronic pyoinflammatory process was reproduced in chinchilla rabbits using Staphylococcus aureus 209 Р (АТСС 6538-Р reference-strain. Preliminary sensitizing of animals with inactivated causative agent and repeated infection with the reference-strain made it possible to work out reproducible model of chronic tonsillitis. Adequacy of chronic tonsillitis development was confirmed by the results of microbiological and pathomorphological researchers. The proposed laboratory model can be used for solving of theoretical and practical medicine and pharmacology topical problems.

  19. The Computer-Aided Analytic Process Model. Operations Handbook for the Analytic Process Model Demonstration Package

    Science.gov (United States)

    1986-01-01

    Research Note 86-06 THE COMPUTER-AIDED ANALYTIC PROCESS MODEL : OPERATIONS HANDBOOK FOR THE ANALYTIC PROCESS MODEL DE ONSTRATION PACKAGE Ronald G...ic Process Model ; Operations Handbook; Tutorial; Apple; Systems Taxonomy Mod--l; Training System; Bradl1ey infantry Fighting * Vehicle; BIFV...8217. . . . . . . .. . . . . . . . . . . . . . . . * - ~ . - - * m- .. . . . . . . item 20. Abstract -continued companion volume-- "The Analytic Process Model for

  20. The R Package threg to Implement Threshold Regression Models

    Directory of Open Access Journals (Sweden)

    Tao Xiao

    2015-08-01

    This new package includes four functions: threg, and the methods hr, predict and plot for threg objects returned by threg. The threg function is the model-fitting function which is used to calculate regression coefficient estimates, asymptotic standard errors and p values. The hr method for threg objects is the hazard-ratio calculation function which provides the estimates of hazard ratios at selected time points for specified scenarios (based on given categories or value settings of covariates. The predict method for threg objects is used for prediction. And the plot method for threg objects provides plots for curves of estimated hazard functions, survival functions and probability density functions of the first-hitting-time; function curves corresponding to different scenarios can be overlaid in the same plot for comparison to give additional research insights.

  1. Using Laboratory Experimental Auctions in Marketing Research: A Case Study of New Packaging for Fresh Beef

    OpenAIRE

    Elizabeth Hoffman; Menkhaus, Dale J.; Dipankar Chakravarti; Field, Ray A.; Whipple, Glen D.

    1993-01-01

    This paper illustrates the use of laboratory experimental auctions in a pretest market research program for new products. We review the experimental auctions literature, discuss the range of auction mechanisms available and present the advantages and disadvantages of using a particular mechanism for a laboratory pretest market. We then present a step-by-step example of how a theoretically incentive compatible auction mechanism (fifth-price, sealed-bid) was used in a laboratory pretest market ...

  2. Thermo-mechanical model optimization of HB-LED packaging

    NARCIS (Netherlands)

    Yuan, C.A.; Erinc, M.; Gielen, A.W.J.; Waal, A. van der; Driel, W. van; Zhang, K.

    2011-01-01

    Lighting is an advancing phenomenon both on the technology and on the market level due to the rapid development of the solid state lighting technology. The efforts in improving the efficacy of high brightness LED's (HB-LED) have concentrated on the packaging architecture. Packaging plays a significa

  3. Aluminum Laminates in Beverage Packaging: Models and Experiences

    Directory of Open Access Journals (Sweden)

    Gabriella Bolzon

    2015-08-01

    Full Text Available Aluminum laminates are among the main components of beverage packaging. These layered material systems are coupled to paperboard plies except in the cap opening area, where the human force limit sets a requirement on the material properties to allow open-ability and the mechanical characteristics are of particular interest. Experimental investigations have been carried out on this composite and on its components by either traditional or full-field measurement techniques. The interpretation of the collected data has been supported by the simulation of the performed tests considering either a homogenized material model or the individual laminate layers. However, different results may be recovered from similar samples due to physical factors like the material processing route and the embedded defectiveness. In turn, the conclusions may vary depending on the model assumptions. This contribution focuses on the physical effects and on the modeling of the large localized deformation induced by material singularities. This topic is discussed at the light of some experimental results.

  4. Highly-optimized TWSM software package for seismic diffraction modeling adapted for GPU-cluster

    Science.gov (United States)

    Zyatkov, Nikolay; Ayzenberg, Alena; Aizenberg, Arkady

    2015-04-01

    Oil producing companies concern to increase resolution capability of seismic data for complex oil-and-gas bearing deposits connected with salt domes, basalt traps, reefs, lenses, etc. Known methods of seismic wave theory define shape of hydrocarbon accumulation with nonsufficient resolution, since they do not account for multiple diffractions explicitly. We elaborate alternative seismic wave theory in terms of operators of propagation in layers and reflection-transmission at curved interfaces. Approximation of this theory is realized in the seismic frequency range as the Tip-Wave Superposition Method (TWSM). TWSM based on the operator theory allows to evaluate of wavefield in bounded domains/layers with geometrical shadow zones (in nature it can be: salt domes, basalt traps, reefs, lenses, etc.) accounting for so-called cascade diffraction. Cascade diffraction includes edge waves from sharp edges, creeping waves near concave parts of interfaces, waves of the whispering galleries near convex parts of interfaces, etc. The basic algorithm of TWSM package is based on multiplication of large-size matrices (make hundreds of terabytes in size). We use advanced information technologies for effective realization of numerical procedures of the TWSM. In particular, we actively use NVIDIA CUDA technology and GPU accelerators allowing to significantly improve the performance of the TWSM software package, that is important in using it for direct and inverse problems. The accuracy, stability and efficiency of the algorithm are justified by numerical examples with curved interfaces. TWSM package and its separate components can be used in different modeling tasks such as planning of acquisition systems, physical interpretation of laboratory modeling, modeling of individual waves of different types and in some inverse tasks such as imaging in case of laterally inhomogeneous overburden, AVO inversion.

  5. Implementation of New Process Models for Tailored Polymer Composite Structures into Processing Software Packages

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, Ba Nghiep; Jin, Xiaoshi; Wang, Jin; Phelps, Jay; Tucker III, Charles L.; Kunc, Vlastimil; Bapanapalli, Satish K.; Smith, Mark T.

    2010-02-23

    This report describes the work conducted under the Cooperative Research and Development Agreement (CRADA) (Nr. 260) between the Pacific Northwest National Laboratory (PNNL) and Autodesk, Inc. to develop and implement process models for injection-molded long-fiber thermoplastics (LFTs) in processing software packages. The structure of this report is organized as follows. After the Introduction Section (Section 1), Section 2 summarizes the current fiber orientation models developed for injection-molded short-fiber thermoplastics (SFTs). Section 3 provides an assessment of these models to determine their capabilities and limitations, and the developments needed for injection-molded LFTs. Section 4 then focuses on the development of a new fiber orientation model for LFTs. This model is termed the anisotropic rotary diffusion - reduced strain closure (ARD-RSC) model as it explores the concept of anisotropic rotary diffusion to capture the fiber-fiber interaction in long-fiber suspensions and uses the reduced strain closure method of Wang et al. to slow down the orientation kinetics in concentrated suspensions. In contrast to fiber orientation modeling, before this project, no standard model was developed to predict the fiber length distribution in molded fiber composites. Section 5 is therefore devoted to the development of a fiber length attrition model in the mold. Sections 6 and 7 address the implementations of the models in AMI, and the conclusions drawn from this work is presented in Section 8.

  6. AN ADA LINEAR ALGEBRA PACKAGE MODELED AFTER HAL/S

    Science.gov (United States)

    Klumpp, A. R.

    1994-01-01

    This package extends the Ada programming language to include linear algebra capabilities similar to those of the HAL/S programming language. The package is designed for avionics applications such as Space Station flight software. In addition to the HAL/S built-in functions, the package incorporates the quaternion functions used in the Shuttle and Galileo projects, and routines from LINPAK that solve systems of equations involving general square matrices. Language conventions in this package follow those of HAL/S to the maximum extent practical and minimize the effort required for writing new avionics software and translating existent software into Ada. Valid numeric types in this package include scalar, vector, matrix, and quaternion declarations. (Quaternions are fourcomponent vectors used in representing motion between two coordinate frames). Single precision and double precision floating point arithmetic is available in addition to the standard double precision integer manipulation. Infix operators are used instead of function calls to define dot products, cross products, quaternion products, and mixed scalar-vector, scalar-matrix, and vector-matrix products. The package contains two generic programs: one for floating point, and one for integer. The actual component type is passed as a formal parameter to the generic linear algebra package. The procedures for solving systems of linear equations defined by general matrices include GEFA, GECO, GESL, and GIDI. The HAL/S functions include ABVAL, UNIT, TRACE, DET, INVERSE, TRANSPOSE, GET, PUT, FETCH, PLACE, and IDENTITY. This package is written in Ada (Version 1.2) for batch execution and is machine independent. The linear algebra software depends on nothing outside the Ada language except for a call to a square root function for floating point scalars (such as SQRT in the DEC VAX MATHLIB library). This program was developed in 1989, and is a copyrighted work with all copyright vested in NASA.

  7. AN ADA LINEAR ALGEBRA PACKAGE MODELED AFTER HAL/S

    Science.gov (United States)

    Klumpp, A. R.

    1994-01-01

    This package extends the Ada programming language to include linear algebra capabilities similar to those of the HAL/S programming language. The package is designed for avionics applications such as Space Station flight software. In addition to the HAL/S built-in functions, the package incorporates the quaternion functions used in the Shuttle and Galileo projects, and routines from LINPAK that solve systems of equations involving general square matrices. Language conventions in this package follow those of HAL/S to the maximum extent practical and minimize the effort required for writing new avionics software and translating existent software into Ada. Valid numeric types in this package include scalar, vector, matrix, and quaternion declarations. (Quaternions are fourcomponent vectors used in representing motion between two coordinate frames). Single precision and double precision floating point arithmetic is available in addition to the standard double precision integer manipulation. Infix operators are used instead of function calls to define dot products, cross products, quaternion products, and mixed scalar-vector, scalar-matrix, and vector-matrix products. The package contains two generic programs: one for floating point, and one for integer. The actual component type is passed as a formal parameter to the generic linear algebra package. The procedures for solving systems of linear equations defined by general matrices include GEFA, GECO, GESL, and GIDI. The HAL/S functions include ABVAL, UNIT, TRACE, DET, INVERSE, TRANSPOSE, GET, PUT, FETCH, PLACE, and IDENTITY. This package is written in Ada (Version 1.2) for batch execution and is machine independent. The linear algebra software depends on nothing outside the Ada language except for a call to a square root function for floating point scalars (such as SQRT in the DEC VAX MATHLIB library). This program was developed in 1989, and is a copyrighted work with all copyright vested in NASA.

  8. Analysis of Ecodesign Implementation and Solutions for Packaging Waste System by Using System Dynamics Modeling

    Science.gov (United States)

    Berzina, Alise; Dace, Elina; Bazbauers, Gatis

    2010-01-01

    This paper discusses the findings of a research project which explored the packaging waste management system in Latvia. The paper focuses on identifying how the policy mechanisms can promote ecodesign implementation and material efficiency improvement and therefore reduce the rate of packaging waste accumulation in landfill. The method used for analyzing the packaging waste management policies is system dynamics modeling. The main conclusion is that the existing legislative instruments can be used to create an effective policy for ecodesign implementation but substantially higher tax rates on packaging materials and waste disposal than the existing have to be applied.

  9. A model for laboratory tech transfer investment

    Energy Technology Data Exchange (ETDEWEB)

    Otey, G.R.; Carson, C.C.; Bomber, T.M.; Rogers, J.D.

    1994-06-01

    A simple model has been developed to address a pragmatic question: What fraction of its research and development budget should a national laboratory devote to enhancing technology in the private sector? In dealing with lab-wide budgets in an aggregate sense, the model uses three parameters - fraction of lab R&D transferable to industry, transfer efficiency and payback to laboratory missions - to partition fixed R&D resources between technology transfer and core missions. It is a steady-state model in that the transfer process is assumed to work in equilibrium with technology generation. The results presented should be of use to those engaged in managing and overseeing federal laboratory technology transfer activities.

  10. Laboratory Modeling of Aspects of Large Fires,

    Science.gov (United States)

    1984-04-30

    7 -7 g~L AD-A153 152 DNA-TR- 84-18 LABORATORY MODELING OF ASPECTS OF LARGE FIRES G.F. Carrier "URARY F.E. Fendell b DVSO R.D. Fleeter N. Got L.M...I1I TITLE (include Socurty Olassihicarion) LABORATORY MODELING OF ASPECTS OF LARGE FIRES 12. PERSONAL AUrHoR(S G.F. Carrier F.E. Fendell R.D. Fleeter N...Motorbuch Verlag.___ Caidin, M. (1960). A Torch to the Enemy: the Fire Raid on Tokyo. New York, NY: Ballantine. Carrier, G. F., Fendell , F. E., and

  11. ShapeSelectForest: a new r package for modeling landsat time series

    Science.gov (United States)

    Mary Meyer; Xiyue Liao; Gretchen Moisen; Elizabeth. Freeman

    2015-01-01

    We present a new R package called ShapeSelectForest recently posted to the Comprehensive R Archival Network. The package was developed to fit nonparametric shape-restricted regression splines to time series of Landsat imagery for the purpose of modeling, mapping, and monitoring annual forest disturbance dynamics over nearly three decades. For each pixel and spectral...

  12. DMU - A Package for Analyzing Multivariate Mixed Models in quantitative Genetics and Genomics

    DEFF Research Database (Denmark)

    Madsen, Per; Jensen, Just; Labouriau, Rodrigo;

    The DMU-package for Analyzing Multivariate Mixed Models has been developed over a period of more than 25 years. This paper gives an overview of new features and the recent developments around the DMU-package, including: Genomic prediction (SNP-BLUP, G-BLUP and “One-Step”), Genome-wide association...

  13. Advanced parametrical modelling of 24 GHz radar sensor IC packaging components

    Science.gov (United States)

    Kazemzadeh, R.; John, W.; Wellmann, J.; Bala, U. B.; Thiede, A.

    2011-08-01

    This paper deals with the development of an advanced parametrical modelling concept for packaging components of a 24 GHz radar sensor IC used in automotive driver assistance systems. For fast and efficient design of packages for system-in-package modules (SiP), a simplified model for the description of parasitic electromagnetic effects within the package is desirable, as 3-D field computation becomes inefficient due to the high density of conductive elements of the various signal paths in the package. By using lumped element models for the characterization of the conductive components, a fast indication of the design's signal-quality can be gained, but so far does not offer enough flexibility to cover the whole range of geometric arrangements of signal paths in a contemporary package. This work pursues to meet the challenge of developing a flexible and fast package modelling concept by defining parametric lumped-element models for all basic signal path components, e.g. bond wires, vias, strip lines, bumps and balls.

  14. visCOS: An R-package to evaluate model performance of hydrological models

    Science.gov (United States)

    Klotz, Daniel; Herrnegger, Mathew; Wesemann, Johannes; Schulz, Karsten

    2016-04-01

    The evaluation of model performance is a central part of (hydrological) modelling. Much attention has been given to the development of evaluation criteria and diagnostic frameworks. (Klemeš, 1986; Gupta et al., 2008; among many others). Nevertheless, many applications exist for which objective functions do not yet provide satisfying summaries. Thus, the necessity to visualize results arises in order to explore a wider range of model capacities, be it strengths or deficiencies. Visualizations are usually devised for specific projects and these efforts are often not distributed to a broader community (e.g. via open source software packages). Hence, the opportunity to explicitly discuss a state-of-the-art presentation technique is often missed. We therefore present a comprehensive R-package for evaluating model performance by visualizing and exploring different aspects of hydrological time-series. The presented package comprises a set of useful plots and visualization methods, which complement existing packages, such as hydroGOF (Zambrano-Bigiarini et al., 2012). It is derived from practical applications of the hydrological models COSERO and COSEROreg (Kling et al., 2014). visCOS, providing an interface in R, represents an easy-to-use software package for visualizing and assessing model performance and can be implemented in the process of model calibration or model development. The package provides functions to load hydrological data into R, clean the data, process, visualize, explore and finally save the results in a consistent way. Together with an interactive zoom function of the time series, an online calculation of the objective functions for variable time-windows is included. Common hydrological objective functions, such as the Nash-Sutcliffe Efficiency and the Kling-Gupta Efficiency, can also be evaluated and visualized in different ways for defined sub-periods like hydrological years or seasonal sections. Many hydrologists use long-term water-balances as a

  15. Extended Rasch Modeling: The eRm Package for the Application of IRT Models in R

    Directory of Open Access Journals (Sweden)

    Patrick Mair

    2007-02-01

    Full Text Available Item response theory models (IRT are increasingly becoming established in social science research, particularly in the analysis of performance or attitudinal data in psychology, education, medicine, marketing and other fields where testing is relevant. We propose the R package eRm (extended Rasch modeling for computing Rasch models and several extensions. A main characteristic of some IRT models, the Rasch model being the most prominent, concerns the separation of two kinds of parameters, one that describes qualities of the subject under investigation, and the other relates to qualities of the situation under which the response of a subject is observed. Using conditional maximum likelihood (CML estimation both types of parameters may be estimated independently from each other. IRT models are well suited to cope with dichotomous and polytomous responses, where the response categories may be unordered as well as ordered. The incorporation of linear structures allows for modeling the effects of covariates and enables the analysis of repeated categorical measurements. The eRm package fits the following models: the Rasch model, the rating scale model (RSM, and the partial credit model (PCM as well as linear reparameterizations through covariate structures like the linear logistic test model (LLTM, the linear rating scale model (LRSM, and the linear partial credit model (LPCM. We use an unitary, efficient CML approach to estimate the item parameters and their standard errors. Graphical and numeric tools for assessing goodness-of-fit are provided.

  16. Dynamic modelling and PID loop control of an oil-injected screw compressor package

    Science.gov (United States)

    Poli, G. W.; Milligan, W. J.; McKenna, P.

    2017-08-01

    A significant amount of time is spent tuning the PID (Proportional, Integral and Derivative) control loops of a screw compressor package due to the unique characteristics of the system. Common mistakes incurred during the tuning of a PID control loop include improper PID algorithm selection and unsuitable tuning parameters of the system resulting in erratic and inefficient operation. This paper details the design and development of software that aims to dynamically model the operation of a single stage oil injected screw compressor package deployed in upstream oil and gas applications. The developed software will be used to assess and accurately tune PID control loops present on the screw compressor package employed in controlling the oil pressures, temperatures and gas pressures, in a bid to improve control of the operation of the screw compressor package. Other applications of the modelling software will include its use as an evaluation tool that can estimate compressor package performance during start up, shutdown and emergency shutdown processes. The paper first details the study into the fundamental operational characteristics of each of the components present on the API 619 screw compressor package and then discusses the creation of a dynamic screw compressor model within the MATLAB/Simulink software suite. The paper concludes by verifying and assessing the accuracy of the created compressor model using data collected from physical screw compressor packages.

  17. PATRAM '92: 10th international symposium on the packaging and transportation of radioactive materials [Papers presented by Sandia National Laboratories

    Energy Technology Data Exchange (ETDEWEB)

    None

    1992-01-01

    This document provides the papers presented by Sandia Laboratories at PATRAM '92, the tenth International symposium on the Packaging and Transportation of Radioactive Materials held September 13--18, 1992 in Yokohama City, Japan. Individual papers have been cataloged separately. (FL)

  18. truncSP: An R Package for Estimation of Semi-Parametric Truncated Linear Regression Models

    Directory of Open Access Journals (Sweden)

    Maria Karlsson

    2014-05-01

    Full Text Available Problems with truncated data occur in many areas, complicating estimation and inference. Regarding linear regression models, the ordinary least squares estimator is inconsistent and biased for these types of data and is therefore unsuitable for use. Alternative estimators, designed for the estimation of truncated regression models, have been developed. This paper presents the R package truncSP. The package contains functions for the estimation of semi-parametric truncated linear regression models using three different estimators: the symmetrically trimmed least squares, quadratic mode, and left truncated estimators, all of which have been shown to have good asymptotic and ?nite sample properties. The package also provides functions for the analysis of the estimated models. Data from the environmental sciences are used to illustrate the functions in the package.

  19. A critical review of constitutive models for solders in electronic packaging

    National Research Council Canada - National Science Library

    Chen, Gang; Zhao, Xiaochen; Wu, Hao

    2017-01-01

    .... Because the failure of the whole electronic packaging is often induced by the failure of solders, modeling and simulation of solder joint performance are quite important in ensuring the quality...

  20. Use of GEANT4 programme package for radiation technological modeling problems

    CERN Document Server

    Bratchenko, M I

    2001-01-01

    The results of pilot computer experiments directed toward the application of Geant4 package for modeling of gamma radiation dose distributions in homogeneous phantoms are presented. we demonstrate the potential of the package it self and of the developed add-on software modules for the calculations of three-dimensional absorbed dose distributions taking into account the design and geometry of model irradiators and phantoms.

  1. Effects of deceptive packaging and product involvement on purchase intention: an elaboration likelihood model perspective.

    Science.gov (United States)

    Lammers, H B

    2000-04-01

    From an Elaboration Likelihood Model perspective, it was hypothesized that postexposure awareness of deceptive packaging claims would have a greater negative effect on scores for purchase intention by consumers lowly involved rather than highly involved with a product (n = 40). Undergraduates who were classified as either highly or lowly (ns = 20 and 20) involved with M&Ms examined either a deceptive or non-deceptive package design for M&Ms candy and were subsequently informed of the deception employed in the packaging before finally rating their intention to purchase. As anticipated, highly deceived subjects who were low in involvement rated intention to purchase lower than their highly involved peers. Overall, the results attest to the robustness of the model and suggest that the model has implications beyond advertising effects and into packaging effects.

  2. Packaging tomorrow : modelling the material input for European packaging in the 21st century

    NARCIS (Netherlands)

    Hekkert, M.P.; Joosten, L.A.J.; Worrell, E.

    2006-01-01

    This report is a result of the MATTER project (MATerials Technology for CO2 Emission Reduction). The project focuses on CO2 emission reductions that are related to the Western European materials system. The total impact of the reduction options for different scenario's will be modeled in MARKAL (MAR

  3. CML based estimation of extended Rasch models with the eRm package in R

    Directory of Open Access Journals (Sweden)

    PATRICK MAIR

    2007-03-01

    Full Text Available This paper presents an open source tool for computing extended Rasch models. It is realized in R (R Development Core Team, 2006 and available as package eRm. In addition to ordinary Rasch models extended models such as linear logistic test models, (linear rating scale models and (linear partial credit models can be estimated. A striking feature of this package is the implementation of conditional maximum likelihood estimation techniques which relate directly to Rasch's original concept of specific objectivity. The mathematical and epistemological benefits of this estimation method are discussed. Moreover, the capabilities of the eRm routine with respect to structural item response designs are demonstrated.

  4. Model-grid and hydraulic-property data arrays of the MULT package of the Central Valley Hydrologic Model

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This digital dataset defines the model-grid and hydraulic-property data arrays of the Multiplier (MULT) Package used in the transient hydrologic model of the Central...

  5. Laboratory constraints on models of earthquake recurrence

    Science.gov (United States)

    Beeler, Nicholas M.; Tullis, Terry; Junger, Jenni; Kilgore, Brian D.; Goldsby, David L.

    2014-01-01

    In this study, rock friction ‘stick-slip’ experiments are used to develop constraints on models of earthquake recurrence. Constant-rate loading of bare rock surfaces in high quality experiments produces stick-slip recurrence that is periodic at least to second order. When the loading rate is varied, recurrence is approximately inversely proportional to loading rate. These laboratory events initiate due to a slip rate-dependent process that also determines the size of the stress drop [Dieterich, 1979; Ruina, 1983] and as a consequence, stress drop varies weakly but systematically with loading rate [e.g., Gu and Wong, 1991; Karner and Marone, 2000; McLaskey et al., 2012]. This is especially evident in experiments where the loading rate is changed by orders of magnitude, as is thought to be the loading condition of naturally occurring, small repeating earthquakes driven by afterslip, or low-frequency earthquakes loaded by episodic slip. As follows from the previous studies referred to above, experimentally observed stress drops are well described by a logarithmic dependence on recurrence interval that can be cast as a non-linear slip-predictable model. The fault’s rate dependence of strength is the key physical parameter. Additionally, even at constant loading rate the most reproducible laboratory recurrence is not exactly periodic, unlike existing friction recurrence models. We present example laboratory catalogs that document the variance and show that in large catalogs, even at constant loading rate, stress drop and recurrence co-vary systematically. The origin of this covariance is largely consistent with variability of the dependence of fault strength on slip rate. Laboratory catalogs show aspects of both slip and time predictability and successive stress drops are strongly correlated indicating a ‘memory’ of prior slip history that extends over at least one recurrence cycle.

  6. Laboratory animal models for esophageal cancer

    Directory of Open Access Journals (Sweden)

    Dhanya Venugopalan Nair

    2016-11-01

    Full Text Available The incidence of esophageal cancer is rapidly increasing especially in developing countries. The major risk factors include unhealthy lifestyle practices such as alcohol consumption, smoking, and chewing tobacco to name a few. Diagnosis at an advanced stage and poor prognosis make esophageal cancer one of the most lethal diseases. These factors have urged further research in understanding the pathophysiology of the disease. Animal models not only aid in understanding the molecular pathogenesis of esophageal cancer but also help in developing therapeutic interventions for the disease. This review throws light on the various recent laboratory animal models for esophageal cancer.

  7. Pyrolysis of aseptic packages (tetrapak) in a laboratory screw type reactor and secondary thermal/catalytic tar decomposition.

    Science.gov (United States)

    Haydary, J; Susa, D; Dudáš, J

    2013-05-01

    Pyrolysis of aseptic packages (tetrapak cartons) in a laboratory apparatus using a flow screw type reactor and a secondary catalytic reactor for tar cracking was studied. The pyrolysis experiments were realized at temperatures ranging from 650 °C to 850 °C aimed at maximizing of the amount of the gas product and reducing its tar content. Distribution of tetrapak into the product yields at different conditions was obtained. The presence of H2, CO, CH4, CO2 and light hydrocarbons, HCx, in the gas product was observed. The Aluminum foil was easily separated from the solid product. The rest part of char was characterized by proximate and elemental analysis and calorimetric measurements. The total organic carbon in the tar product was estimated by elemental analysis of tars. Two types of catalysts (dolomite and red clay marked AFRC) were used for catalytic thermal tar decomposition. Three series of experiments (without catalyst in a secondary cracking reactor, with dolomite and with AFRC) at temperatures of 650, 700, 750, 800 and 850 °C were carried out. Both types of catalysts have significantly affected the content of tars and other components in pyrolytic gases. The effect of catalyst on the tetrapack distribution into the product yield on the composition of gas and on the total organic carbon in the tar product is presented in this work.

  8. PyXel: A Python Package for Astronomical X-ray Data Modeling

    Science.gov (United States)

    Ogrean, Georgiana

    2016-06-01

    PyXel is an new Python package for modeling astronomical X-ray imaging data. It is built on NumPy, SciPy, matplotlib, and Astropy, and distributed under an open-source license. The package aims to provide a common set of image analysis tools for astronomers working with extended X-ray sources. I will present an overview of its existing and planned features, and analysis examples based on public Chandra data.

  9. Technical Review Report for the Safety Analysis Report for Packaging Model 9977 S-SARP-G-00001 Revision 2

    Energy Technology Data Exchange (ETDEWEB)

    DiSabatino, A; Hafner, R; West, M

    2007-10-04

    This Technical Review Report (TRR) summarizes the review findings for the Safety Analysis Report for Packaging (SARP) for the Model 9977 B(M)F-96 shipping container. The content analyzed for this submittal is Content Envelope C.1, Heat Sources, in assemblies of Radioisotope Thermoelectric Generators or food-pack cans. The SARP under review, i.e., S-SARP-G-00001, Revision 2 (August 2007), was originally referred to as the General Purpose Fissile Material Package. The review presented in this TRR was performed using the methods outlined in Revision 3 of the Department of Energy's (DOE's) Packaging Review Guide (PRG) for Reviewing Safety Analysis Reports for Packages. The format of the SARP follows that specified in Revision 2 of the Nuclear Regulatory Commission's, Regulatory Guide 7.9, i.e., Standard Format and Content of Part 71 Applications for Approval of Packages for Radioactive Material. Although the two documents are similar in their content, they are not identical. Formatting differences have been noted in this TRR, where appropriate. The Model 9977 Package is a 35-gallon drum package design that has evolved from a family of packages designed by DOE contractors at the Savannah River Site. The Model 9977 Package design includes a single, 6-inch diameter, stainless steel pressure vessel containment system (i.e., the 6CV) that was designed and fabricated in accordance with Section III, Subsection NB, of the American Society of Mechanical Engineers Boiler & Pressure Vessel Code. The earlier package designs, i.e., the Model 9965, 9966, 9967 and 9968 Packages, were originally designed and certified in the 1980s. In the 1990s, updated package designs that incorporated design features consistent with new safety requirements, based on International Atomic Energy Agency guidelines, were proposed. The updated package designs were the Model 9972, 9973, 9974 and 9975 Packages, respectively. The Model 9975 Package was certified by the Packaging Certification

  10. Modular modeling system for building distributed hydrologic models with a user-friendly software package

    Science.gov (United States)

    Wi, S.; Ray, P. A.; Brown, C.

    2015-12-01

    A software package developed to facilitate building distributed hydrologic models in a modular modeling system is presented. The software package provides a user-friendly graphical user interface that eases its practical use in water resources-related research and practice. The modular modeling system organizes the options available to users when assembling models according to the stages of hydrological cycle, such as potential evapotranspiration, soil moisture accounting, and snow/glacier melting processes. The software is intended to be a comprehensive tool that simplifies the task of developing, calibrating, validating, and using hydrologic models through the inclusion of intelligent automation to minimize user effort, and reduce opportunities for error. Processes so far automated include the definition of system boundaries (i.e., watershed delineation), climate and geographical input generation, and parameter calibration. Built-in post-processing toolkits greatly improve the functionality of the software as a decision support tool for water resources system management and planning. Example post-processing toolkits enable streamflow simulation at ungauged sites with predefined model parameters, and perform climate change risk assessment by means of the decision scaling approach. The software is validated through application to watersheds representing a variety of hydrologic regimes.

  11. The Langevin Approach: An R Package for Modeling Markov Processes

    Directory of Open Access Journals (Sweden)

    Philip Rinn

    2016-08-01

    Full Text Available We describe an 'R' package developed by the research group 'Turbulence, Wind energy' 'and Stochastics' (TWiSt at the Carl von Ossietzky University of Oldenburg, which extracts the (stochastic evolution equation underlying a set of data or measurements. The method can be directly applied to data sets with one or two stochastic variables. Examples for the one-dimensional and two-dimensional cases are provided. This framework is valid under a small set of conditions which are explicitly presented and which imply simple preliminary test procedures to the data. For Markovian processes involving Gaussian white noise, a stochastic differential equation is derived straightforwardly from the time series and captures the full dynamical properties of the underlying process. Still, even in the case such conditions are not fulfilled, there are alternative versions of this method which we discuss briefly and provide the user with the necessary bibliography.

  12. Modeling sustainable groundwater management: packaging and sequencing of policy interventions.

    Science.gov (United States)

    Esteban, Encarna; Dinar, Ariel

    2013-04-15

    Of the many studies estimating effectiveness of policy reforms most have been considering various types of policy reforms in isolation from each other. Such pattern has also been the case in water resource regulations. In the case of groundwater almost all policy interventions considered in the literature have been implemented individually, without taking into account the possible interactions and impacts among them. In this paper, we focus on two policy instruments: water quota and uniform water tax. The paper demonstrates how packaging and sequencing sets of policy interventions, with possible triggers to initiate their time of implementation, may be more effective in achieving a sustainable groundwater management than single policies when environmental externalities exist. The policy instruments are applied to the Western la Mancha aquifer in Southeast Spain, a major aquifer that is managed by a command and control approach. Copyright © 2013 Elsevier Ltd. All rights reserved.

  13. The Langevin Approach: An R Package for Modeling Markov Processes

    CERN Document Server

    Rinn, Philip; Wächter, Matthias; Peinke, Joachim

    2016-01-01

    We describe an R package developed by the research group Turbulence, Wind energy and Stochastics (TWiSt) at the Carl von Ossietzky University of Oldenburg, which extracts the (stochastic) evolution equation underlying a set of data or measurements. The method can be directly applied to data sets with one or two stochastic variables. Examples for the one-dimensional and two-dimensional cases are provided. This framework is valid under a small set of conditions which are explicitly presented and which imply simple preliminary test procedures to the data. For Markovian processes involving Gaussian white noise, a stochastic differential equation is derived straightforwardly from the time series and captures the full dynamical properties of the underlying process. Still, even in the case such conditions are not fulfilled, there are alternative versions of this method which we discuss briefly and provide the user with the necessary bibliography.

  14. Safety analysis report for packaging, Oak Ridge Y-12 Plant, model DC-1 package with HEU oxide contents. Change pages for Rev.1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-01-18

    This Safety Analysis Report for Packaging for the Oak Ridge Y-12 Plant for the Model DC-1 package with highly enriched uranium (HEU) oxide contents has been prepared in accordance with governing regulations form the Nuclear Regulatory Commission and the Department of Transportation and orders from the Department of energy. The fundamental safety requirements addressed by these regulations and orders pertain to the containment of radioactive material, radiation shielding, and nuclear subcriticality. This report demonstrates how these requirements are met.

  15. A MATLAB Package for Markov Chain Monte Carlo with a Multi-Unidimensional IRT Model

    Directory of Open Access Journals (Sweden)

    Yanyan Sheng

    2008-11-01

    Full Text Available Unidimensional item response theory (IRT models are useful when each item is designed to measure some facet of a unified latent trait. In practical applications, items are not necessarily measuring the same underlying trait, and hence the more general multi-unidimensional model should be considered. This paper provides the requisite information and description of software that implements the Gibbs sampler for such models with two item parameters and a normal ogive form. The software developed is written in the MATLAB package IRTmu2no. The package is flexible enough to allow a user the choice to simulate binary response data with multiple dimensions, set the number of total or burn-in iterations, specify starting values or prior distributions for model parameters, check convergence of the Markov chain, as well as obtain Bayesian fit statistics. Illustrative examples are provided to demonstrate and validate the use of the software package.

  16. Random forest methodology for model-based recursive partitioning: the mobForest package for R

    OpenAIRE

    Garge, Nikhil R; Bobashev, Georgiy; Eggleston, Barry

    2013-01-01

    Background Recursive partitioning is a non-parametric modeling technique, widely used in regression and classification problems. Model-based recursive partitioning is used to identify groups of observations with similar values of parameters of the model of interest. The mob() function in the party package in R implements model-based recursive partitioning method. This method produces predictions based on single tree models. Predictions obtained through single tree models are very sensitive to...

  17. Development and application of compact models of packages based on DELPHI methodology

    CERN Document Server

    Parry, J; Shidore, S

    1997-01-01

    The accurate prediction of the temperatures of critical electronic parts at the package- board- and system-level is seriously hampered by the lack of reliable, standardised input data for the characterisation of the thermal $9 behaviour of these parts. The recently completed collaborative European project, DELPHI has been concerned with the creation and experimental validation of thermal models (both detailed and compact) of a range of electronic parts, $9 including mono-chip packages. This paper demonstrates the reliable performance of thermal compact models in a range of applications, by comparison with the detailed models from which they were derived. (31 refs).

  18. Modeling and simulation for microelectronic packaging assembly manufacturing, reliability and testing

    CERN Document Server

    Liu, Sheng

    2011-01-01

    Although there is increasing need for modeling and simulation in the IC package design phase, most assembly processes and various reliability tests are still based on the time consuming ""test and try out"" method to obtain the best solution. Modeling and simulation can easily ensure virtual Design of Experiments (DoE) to achieve the optimal solution. This has greatly reduced the cost and production time, especially for new product development. Using modeling and simulation will become increasingly necessary for future advances in 3D package development.  In this book, Liu and Liu allow people

  19. ltm: An R Package for Latent Variable Modeling and Item Response Analysis

    Directory of Open Access Journals (Sweden)

    Dimitris Rizopoulos

    2006-11-01

    Full Text Available The R package ltm has been developed for the analysis of multivariate dichotomous and polytomous data using latent variable models, under the Item Response Theory approach. For dichotomous data the Rasch, the Two-Parameter Logistic, and Birnbaum's Three-Parameter models have been implemented, whereas for polytomous data Semejima's Graded Response model is available. Parameter estimates are obtained under marginal maximum likelihood using the Gauss-Hermite quadrature rule. The capabilities and features of the package are illustrated using two real data examples.

  20. [download] (969dlmap: An R Package for Mixed Model QTL and Association Analysis

    Directory of Open Access Journals (Sweden)

    B. Emma Huang

    2012-08-01

    Full Text Available dlmap is a software package capable of mapping quantitative trait loci (QTL in a variety of genetic studies. Unlike most other QTL mapping packages, dlmap is built on a linear mixed model platform, and thus can simultaneously handle multiple sources of genetic and environmental variation. Furthermore, it can accommodate both experimental crosses and association mapping populations within a versatile modeling framework. The software implements a mapping algorithm with separate detection and localization stages in a user-friendly manner. It accepts data in various common formats, has a flexible modeling environment, and summarizes results both graphically and numerically.

  1. The Systems Biology Markup Language (SBML) Level 3 Package: Qualitative Models, Version 1, Release 1.

    Science.gov (United States)

    Chaouiya, Claudine; Keating, Sarah M; Berenguier, Duncan; Naldi, Aurélien; Thieffry, Denis; van Iersel, Martijn P; Le Novère, Nicolas; Helikar, Tomáš

    2015-09-04

    Quantitative methods for modelling biological networks require an in-depth knowledge of the biochemical reactions and their stoichiometric and kinetic parameters. In many practical cases, this knowledge is missing. This has led to the development of several qualitative modelling methods using information such as, for example, gene expression data coming from functional genomic experiments. The SBML Level 3 Version 1 Core specification does not provide a mechanism for explicitly encoding qualitative models, but it does provide a mechanism for SBML packages to extend the Core specification and add additional syntactical constructs. The SBML Qualitative Models package for SBML Level 3 adds features so that qualitative models can be directly and explicitly encoded. The approach taken in this package is essentially based on the definition of regulatory or influence graphs. The SBML Qualitative Models package defines the structure and syntax necessary to describe qualitative models that associate discrete levels of activities with entity pools and the transitions between states that describe the processes involved. This is particularly suited to logical models (Boolean or multi-valued) and some classes of Petri net models can be encoded with the approach.

  2. Software Engineering Laboratory (SEL) cleanroom process model

    Science.gov (United States)

    Green, Scott; Basili, Victor; Godfrey, Sally; Mcgarry, Frank; Pajerski, Rose; Waligora, Sharon

    1991-01-01

    The Software Engineering Laboratory (SEL) cleanroom process model is described. The term 'cleanroom' originates in the integrated circuit (IC) production process, where IC's are assembled in dust free 'clean rooms' to prevent the destructive effects of dust. When applying the clean room methodology to the development of software systems, the primary focus is on software defect prevention rather than defect removal. The model is based on data and analysis from previous cleanroom efforts within the SEL and is tailored to serve as a guideline in applying the methodology to future production software efforts. The phases that are part of the process model life cycle from the delivery of requirements to the start of acceptance testing are described. For each defined phase, a set of specific activities is discussed, and the appropriate data flow is described. Pertinent managerial issues, key similarities and differences between the SEL's cleanroom process model and the standard development approach used on SEL projects, and significant lessons learned from prior cleanroom projects are presented. It is intended that the process model described here will be further tailored as additional SEL cleanroom projects are analyzed.

  3. 'spup' - an R package for uncertainty propagation analysis in spatial environmental modelling

    Science.gov (United States)

    Sawicka, Kasia; Heuvelink, Gerard

    2017-04-01

    Computer models have become a crucial tool in engineering and environmental sciences for simulating the behaviour of complex static and dynamic systems. However, while many models are deterministic, the uncertainty in their predictions needs to be estimated before they are used for decision support. Currently, advances in uncertainty propagation and assessment have been paralleled by a growing number of software tools for uncertainty analysis, but none has gained recognition for a universal applicability and being able to deal with case studies with spatial models and spatial model inputs. Due to the growing popularity and applicability of the open source R programming language we undertook a project to develop an R package that facilitates uncertainty propagation analysis in spatial environmental modelling. In particular, the 'spup' package provides functions for examining the uncertainty propagation starting from input data and model parameters, via the environmental model onto model predictions. The functions include uncertainty model specification, stochastic simulation and propagation of uncertainty using Monte Carlo (MC) techniques, as well as several uncertainty visualization functions. Uncertain environmental variables are represented in the package as objects whose attribute values may be uncertain and described by probability distributions. Both numerical and categorical data types are handled. Spatial auto-correlation within an attribute and cross-correlation between attributes is also accommodated for. For uncertainty propagation the package has implemented the MC approach with efficient sampling algorithms, i.e. stratified random sampling and Latin hypercube sampling. The design includes facilitation of parallel computing to speed up MC computation. The MC realizations may be used as an input to the environmental models called from R, or externally. Selected visualization methods that are understandable by non-experts with limited background in

  4. 'spup' - an R package for uncertainty propagation in spatial environmental modelling

    Science.gov (United States)

    Sawicka, Kasia; Heuvelink, Gerard

    2016-04-01

    Computer models have become a crucial tool in engineering and environmental sciences for simulating the behaviour of complex static and dynamic systems. However, while many models are deterministic, the uncertainty in their predictions needs to be estimated before they are used for decision support. Currently, advances in uncertainty propagation and assessment have been paralleled by a growing number of software tools for uncertainty analysis, but none has gained recognition for a universal applicability, including case studies with spatial models and spatial model inputs. Due to the growing popularity and applicability of the open source R programming language we undertook a project to develop an R package that facilitates uncertainty propagation analysis in spatial environmental modelling. In particular, the 'spup' package provides functions for examining the uncertainty propagation starting from input data and model parameters, via the environmental model onto model predictions. The functions include uncertainty model specification, stochastic simulation and propagation of uncertainty using Monte Carlo (MC) techniques, as well as several uncertainty visualization functions. Uncertain environmental variables are represented in the package as objects whose attribute values may be uncertain and described by probability distributions. Both numerical and categorical data types are handled. Spatial auto-correlation within an attribute and cross-correlation between attributes is also accommodated for. For uncertainty propagation the package has implemented the MC approach with efficient sampling algorithms, i.e. stratified random sampling and Latin hypercube sampling. The design includes facilitation of parallel computing to speed up MC computation. The MC realizations may be used as an input to the environmental models called from R, or externally. Selected static and interactive visualization methods that are understandable by non-experts with limited background in

  5. Independencies Induced from a Graphical Markov Model After Marginalization and Conditioning: The R Package ggm

    Directory of Open Access Journals (Sweden)

    Giovanni M. Marchetti

    2006-02-01

    Full Text Available We describe some functions in the R package ggm to derive from a given Markov model, represented by a directed acyclic graph, different types of graphs induced after marginalizing over and conditioning on some of the variables. The package has a few basic functions that find the essential graph, the induced concentration and covariance graphs, and several types of chain graphs implied by the directed acyclic graph (DAG after grouping and reordering the variables. These functions can be useful to explore the impact of latent variables or of selection effects on a chosen data generating model.

  6. LanHEP - a package for automatic generation of Feynman rules in gauge models

    CERN Document Server

    Semenov, A Yu

    1996-01-01

    We consider the general problem of derivation of the Feynman rules for the matrix elements in momentum representation from the given Lagrangian in coordinate space invariant under the transformation of some gauge group. LanHEP package presented in this paper allows to define in a convenient way the gauge model Lagrangian in canonical form and then to generate automatically the Feynman rules that can be used in the following calculation of the physical processes by means of CompHEP package. The detailed description of LanHEP commands is given and several examples of LanHEP applications (QED, QCD, Standard Model in the t'Hooft-Feynman gauge) are presented.

  7. Safety evaluation for packaging (onsite) for concrete-shielded RHTRU waste drum for the 327 postirradiation testing laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Adkins, H.E.

    1996-10-29

    This safety evaluation for packaging authorizes onsite transport of Type B quantities of radioactive material in the Concrete- Shielded Remote-Handled Transuranic Waste (RH TRU) Drum per WHC-CM-2-14, Hazardous Material Packaging and Shipping. The drum will be used for transport of 327 Building legacy waste from the 300 Area to the Transuranic Waste Storage and Assay Facility in the 200 West Area and on to a Solid Waste Storage Facility, also in the 200 Area.

  8. Drop Test Results for the Combustion Engineering Model No. ABB-2901 Fuel Pellet Package

    Energy Technology Data Exchange (ETDEWEB)

    Hafner, R S; Mok, G C; Hagler, L G

    2004-04-23

    The U.S. Nuclear Regulatory Commission (USNRC) contracted with the Packaging Review Group (PRG) at Lawrence Livermore National Laboratory (LLNL) to conduct a single, 30-ft shallow-angle drop test on the Combustion Engineering ABB-2901 drum-type shipping package. The purpose of the test was to determine if bolted-ring drum closures could fail during shallow-angle drops. The PRG at LLNL planned the test, and Defense Technologies Engineering Division (DTED) personnel from LLNL's Site-300 Test Group executed the plan. The test was conducted in November 2001 using the drop-tower facility at LLNL's Site 300. Two representatives from Westinghouse Electric Company in Columbia, South Carolina (WEC-SC); two USNRC staff members; and three PRG members from LLNL witnessed the preliminary test runs and the final test. The single test clearly demonstrated the vulnerability of the bolted-ring drum closure to shallow-angle drops-the test package's drum closure was easily and totally separated from the drum package. The results of the preliminary test runs and the 30-ft shallow-angle drop test offer valuable qualitative understandings of the shallow-angle impact.

  9. Finite element modelling for the investigation of edge effect in acoustic micro imaging of microelectronic packages

    Science.gov (United States)

    Shen Lee, Chean; Zhang, Guang-Ming; Harvey, David M.; Ma, Hong-Wei; Braden, Derek R.

    2016-02-01

    In acoustic micro imaging of microelectronic packages, edge effect is often presented as artifacts of C-scan images, which may potentially obscure the detection of defects such as cracks and voids in the solder joints. The cause of edge effect is debatable. In this paper, a 2D finite element model is developed on the basis of acoustic micro imaging of a flip-chip package using a 230 MHz focused transducer to investigate acoustic propagation inside the package in attempt to elucidate the fundamental mechanism that causes the edge effect. A virtual transducer is designed in the finite element model to reduce the coupling fluid domain, and its performance is characterised against the physical transducer specification. The numerical results showed that the under bump metallization (UBM) structure inside the package has a significant impact on the edge effect. Simulated wavefields also showed that the edge effect is mainly attributed to the horizontal scatter, which is observed in the interface of silicon die-to-the outer radius of solder bump. The horizontal scatter occurs even for a flip-chip package without the UBM structure.

  10. Release Mathematical Model of Active Agent from Packaging Material into Food

    Directory of Open Access Journals (Sweden)

    Xiuling Huang

    2013-01-01

    Full Text Available Active packaging is an innovative packaging technology by which active compounds are released from the package to enhance the quality and microbial safety for a wide range of foods. The problem of active ingredient release through the bilayer packaging food system is studied from a theoretical viewpoint. A release model is built to provide predictions of concentration and amount of active ingredient. The equations are built based on Fickian diffusion, and numerical solutions are obtained through finite difference. Different diffusion coefficients DP and DC of active ingredient in different packaging layers, partition coefficient kCP at the interface of outer layer and inner layer, partition coefficient kFC at the interface of inner layer and food, and mass transfer coefficient hm at the interface of inner layer and food are considered in the model. The effects of kCP, thicknesses of outer layer and inner layer, CP0, DP, DC, kFC, and hm on the release are discussed. Corresponding conclusions and analysis are given.

  11. Performance of Nonmigratory Iron Chelating Active Packaging Materials in Viscous Model Food Systems.

    Science.gov (United States)

    Roman, Maxine J; Decker, Eric A; Goddard, Julie M

    2015-09-01

    Many packaged food products undergo quality deterioration due to iron promoted oxidative reactions. Recently, we have developed a nonmigratory iron chelating active packaging material that represents a novel approach to inhibit oxidation of foods while addressing consumer demands for "cleanˮ labels. A challenge to the field of nonmigratory active packaging is ensuring that surface-immobilized active agents retain activity in a true food system despite diffusional limitations. Yet, the relationship between food viscosity and nonmigratory active packaging activity retention has never been characterized. The objective of this study was to investigate the influence of food viscosity on iron chelation by a nonmigratory iron chelating active packaging material. Methyl cellulose was added to aqueous buffered iron solutions to yield model systems with viscosities ranging from ∼1 to ∼10(5)  mPa·s, representing viscosities ranging from beverage to mayonnaise. Iron chelation was quantified by material-bound iron content using colorimetry and inductively coupled plasma-optical emission spectrometry (ICP-OES).  Maximum iron chelation was reached in solutions up to viscosity ∼10(2)  mPa·s. In more viscous solutions (up to ∼10(4)  mPa·s), there was a significant decrease in iron chelating capacity (P influence of different food hydrocolloids on the performance of nonmigratory iron chelating active packaging was characterized. Methyl cellulose and carrageenan did not compete with the material for specific iron chelation (P > 0.05). Materials retained 32% to 45% chelating capacity when in contact with competitively chelating hydrocolloids guar gum, locust bean gum, and xanthan gum. This work demonstrates the potential application of nonmigratory iron chelating active packaging in liquid and semi-liquid foods to allow for the removal of synthetic chelators, while maintaining food quality.

  12. Rotating, hydromagnetic laboratory experiment modelling planetary cores

    Science.gov (United States)

    Kelley, Douglas H.

    2009-10-01

    This dissertation describes a series of laboratory experiments motivated by planetary cores and the dynamo effect, the mechanism by which the flow of an electrically conductive fluid can give rise to a spontaneous magnetic field. Our experimental apparatus, meant to be a laboratory model of Earth's core, contains liquid sodium between an inner, solid sphere and an outer, spherical shell. The fluid is driven by the differential rotation of these two boundaries, each of which is connected to a motor. Applying an axial, DC magnetic field, we use a collection of Hall probes to measure the magnetic induction that results from interactions between the applied field and the flowing, conductive fluid. We have observed and identified inertial modes, which are bulk oscillations of the fluid restored by the Coriolis force. Over-reflection at a shear layer is one mechanism capable of exciting such modes, and we have developed predictions of both onset boundaries and mode selection from over-reflection theory which are consistent with our observations. Also, motivated by previous experimental devices that used ferromagnetic boundaries to achieve dynamo action, we have studied the effects of a soft iron (ferromagnetic) inner sphere on our apparatus, again finding inertial waves. We also find that all behaviors are more broadband and generally more nonlinear in the presence of a ferromagnetic boundary. Our results with a soft iron inner sphere have implications for other hydromagnetic experiments with ferromagnetic boundaries, and are appropriate for comparison to numerical simulations as well. From our observations we conclude that inertial modes almost certainly occur in planetary cores and will occur in future rotating experiments. In fact, the predominance of inertial modes in our experiments and in other recent work leads to a new paradigm for rotating turbulence, starkly different from turbulence theories based on assumptions of isotropy and homogeneity, starting instead

  13. An R package for fitting age, period and cohort models

    Directory of Open Access Journals (Sweden)

    Adriano Decarli

    2014-11-01

    Full Text Available In this paper we present the R implementation of a GLIM macro which fits age-period-cohort model following Osmond and Gardner. In addition to the estimates of the corresponding model, owing to the programming capability of R as an object oriented language, methods for printing, plotting and summarizing the results are provided. Furthermore, the researcher has fully access to the output of the main function (apc which returns all the models fitted within the function. It is so possible to critically evaluate the goodness of fit of the resulting model.

  14. Aviation Shipboard Operations Modeling and Simulation (ASOMS) Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Purpose:It is the mission of the Aviation Shipboard Operations Modeling and Simulation (ASOMS) Laboratory to provide a means by which to virtually duplicate products...

  15. Multilevel IRT Modeling in Practice with the Package mlirt

    NARCIS (Netherlands)

    Fox, Jean-Paul

    2007-01-01

    Variance component models are generally accepted for the analysis of hierarchical structured data. A shortcoming is that outcome variables are still treated as measured without an error. Unreliable variables produce biases in the estimates of the other model parameters. The variability of the relati

  16. ergm: A Package to Fit, Simulate and Diagnose Exponential-Family Models for Networks

    Directory of Open Access Journals (Sweden)

    David R. Hunter

    2008-12-01

    Full Text Available We describe some of the capabilities of the ergm package and the statistical theory underlying it. This package contains tools for accomplishing three important, and inter-related, tasks involving exponential-family random graph models (ERGMs: estimation, simulation, and goodness of fit. More precisely, ergm has the capability of approximating a maximum likelihood estimator for an ERGM given a network data set; simulating new network data sets from a fitted ERGM using Markov chain Monte Carlo; and assessing how well a fitted ERGM does at capturing characteristics of a particular network data set.

  17. PyXel: A Python Package for Astronomical X-ray Data Modeling

    Science.gov (United States)

    Ogrean, Georgiana

    2017-01-01

    PyXel is a open-source Python package for modeling astronomical X-ray imaging data. It is primarily built on NumPy, SciPy, Astropy, and emcee. The package aims to provide a common set of image analysis tools for astronomers working with extended X-ray sources. I will present an overview of its features, and analysis examples based on public Chandra data.The code is available for download on GitHub (https://github.com/gogrean/PyXel), and contributions to it are welcome.

  18. airGRteaching: an R-package designed for teaching hydrology with lumped hydrological models

    Science.gov (United States)

    Thirel, Guillaume; Delaigue, Olivier; Coron, Laurent; Andréassian, Vazken; Brigode, Pierre

    2017-04-01

    Lumped hydrological models are useful and convenient tools for research, engineering and educational purposes. They propose catchment-scale representations of the precipitation-discharge relationship. Thanks to their limited data requirements, they can be easily implemented and run. With such models, it is possible to simulate a number of hydrological key processes over the catchment with limited structural and parametric complexity, typically evapotranspiration, runoff, underground losses, etc. The Hydrology Group at Irstea (Antony) has been developing a suite of rainfall-runoff models over the past 30 years. This resulted in a suite of models running at different time steps (from hourly to annual) applicable for various issues including water balance estimation, forecasting, simulation of impacts and scenario testing. Recently, Irstea has developed an easy-to-use R-package (R Core Team, 2016), called airGR (Coron et al., 2016, 2017), to make these models widely available. Although its initial target public was hydrological modellers, the package is already used for educational purposes. Indeed, simple models allow for rapidly visualising the effects of parameterizations and model components on flows hydrographs. In order to avoid the difficulties that students may have when manipulating R and datasets, we developed (Delaigue and Coron, 2016): - Three simplified functions to prepare data, calibrate a model and run a simulation - Simplified and dynamic plot functions - A shiny (Chang et al., 2016) interface that connects this R-package to a browser-based visualisation tool. On this interface, the students can use different hydrological models (including the possibility to use a snow-accounting model), manually modify their parameters and automatically calibrate their parameters with diverse objective functions. One of the visualisation tabs of the interface includes observed precipitation and temperature, simulated snowpack (if any), observed and simulated

  19. Certified reference materials for food packaging specific migration tests: development, validation and modelling

    NARCIS (Netherlands)

    Stoffers, N.H.

    2005-01-01

    Keywords:certified reference materials; diffusion; food contact materials; food packaging; laurolactam; migration modelling; nylon; specific migration This thesis compiles several research topics

  20. Predictive modeling of migration from packaging materials into food products for regulatory purposes

    NARCIS (Netherlands)

    Helmroth, I.E.; Rijk, R.; Dekker, M.; Jongen, W.M.F.

    2002-01-01

    Migration of low-molecular weight compounds is one of the most important problems of packaging plastics and other plastics intended to come into contact with food products. Since migration experiments are time consuming and expensive, predictive modelling has been introduced as a promising alternati

  1. robustlmm: An R Package for Robust Estimation of Linear Mixed-Effects Models

    Directory of Open Access Journals (Sweden)

    Manuel Koller

    2016-12-01

    Full Text Available As any real-life data, data modeled by linear mixed-effects models often contain outliers or other contamination. Even little contamination can drive the classic estimates far away from what they would be without the contamination. At the same time, datasets that require mixed-effects modeling are often complex and large. This makes it difficult to spot contamination. Robust estimation methods aim to solve both problems: to provide estimates where contamination has only little influence and to detect and flag contamination. We introduce an R package, robustlmm, to robustly fit linear mixed-effects models. The package's functions and methods are designed to closely equal those offered by lme4, the R package that implements classic linear mixed-effects model estimation in R. The robust estimation method in robustlmm is based on the random effects contamination model and the central contamination model. Contamination can be detected at all levels of the data. The estimation method does not make any assumption on the data's grouping structure except that the model parameters are estimable. robustlmm supports hierarchical and non-hierarchical (e.g., crossed grouping structures. The robustness of the estimates and their asymptotic efficiency is fully controlled through the function interface. Individual parts (e.g., fixed effects and variance components can be tuned independently. In this tutorial, we show how to fit robust linear mixed-effects models using robustlmm, how to assess the model fit, how to detect outliers, and how to compare different fits.

  2. pyBSM: A Python package for modeling imaging systems

    Science.gov (United States)

    LeMaster, Daniel A.; Eismann, Michael T.

    2017-05-01

    There are components that are common to all electro-optical and infrared imaging system performance models. The purpose of the Python Based Sensor Model (pyBSM) is to provide open source access to these functions for other researchers to build upon. Specifically, pyBSM implements much of the capability found in the ERIM Image Based Sensor Model (IBSM) V2.0 along with some improvements. The paper also includes two use-case examples. First, performance of an airborne imaging system is modeled using the General Image Quality Equation (GIQE). The results are then decomposed into factors affecting noise and resolution. Second, pyBSM is paired with openCV to evaluate performance of an algorithm used to detect objects in an image.

  3. VHDL Models with Usage of the LFSR_PCKG Package

    Directory of Open Access Journals (Sweden)

    J. Mitrych

    2002-04-01

    Full Text Available LFSRs (Linear Feedback Shift Registers are very often used in theBIST (Built-In Self-Test methodology. Implementation of the LFSRs tothe design or application of digital system, which supports BISTtechniques or which only uses these LFSRs, can be done by VHDLlanguage. This paper presents VHDL models of the devices andsubroutines (e.g. test pattern generators, signature analysers. Modelsare based on LFSR structures with usage of the LFSR_PCKG packagedescribed in the (Kovalsky and Vlcek, 2001, which can be usedin the applications supporting BIST techniques. Devices are describedas behavioural and structural models. These models and descriptions canbe used e.g. in the (Kovalsky, 2001. The LFSR_PCKG was modifiedand new approach is presented. Naturally, there are presented somesynthesis conclusions of the VHDL models and applications in thispaper.

  4. A professional development model for medical laboratory scientists working in the microbiology laboratory.

    Science.gov (United States)

    Amerson, Megan H; Pulido, Lila; Garza, Melinda N; Ali, Faheem A; Greenhill, Brandy; Einspahr, Christopher L; Yarsa, Joseph; Sood, Pramilla K; Hu, Peter C

    2012-01-01

    The University of Texas M.D. Anderson Cancer Center, Division of Pathology and Laboratory Medicine is committed to providing the best pathology and medicine through: state-of-the art techniques, progressive ground-breaking research, education and training for the clinical diagnosis and research of cancer and related diseases. After surveying the laboratory staff and other hospital professionals, the Department administrators and Human Resource generalists developed a professional development model for Microbiology to support laboratory skills, behavior, certification, and continual education within its staff. This model sets high standards for the laboratory professionals to allow the labs to work at their fullest potential; it provides organization to training technologists based on complete laboratory needs instead of training technologists in individual areas in which more training is required if the laboratory needs them to work in other areas. This model is a working example for all microbiology based laboratories who want to set high standards and want their staff to be acknowledged for demonstrated excellence and professional development in the laboratory. The PDM model is designed to focus on the needs of the laboratory as well as the laboratory professionals.

  5. Predictive modelling for packaging design: equilibrium modified atmosphere packages of fresh-cut vegetables subjected to a simulated distribution chain.

    Science.gov (United States)

    Jacxsens, L; Devlieghere, F; Debevere, J

    2002-03-01

    The impact of temperature fluctuations in a simulated cold distribution chain, typical of commercial practice, was investigated on both the microbial and sensorial quality of equilibrium modified atmosphere (EMA) packaged minimally processed vegetables. The internal O2 concentration of the designed packages could be predicted for the different steps of the simulated distribution chain by applying an integrated mathematical system. The internal atmosphere in the packages remained in its aerobic range during storage in the chain due to the application of high permeable packaging films for O2 and CO2. Spoilage microorganisms were proliferating fast on minimally processed bell peppers and lettuce. Yeasts showed to be the shelf-life limiting group. Visual properties limited the sensorial shelf-life. Listeria monocytogenes was able to multiply on cucumber slices, survived on minimally processed lettuce and decreased in number on bell peppers due to the combination of low pH and refrigeration. Aeromonas caviae was multiplying on both cucumber slices and mixed lettuce, but was as well inhibited by the low pH of bell peppers. Storage temperature control was found to be of paramount importance for the microbial (spoilage and safety) and sensorial quality evaluation of EMA-packaged minimally processed vegetables.

  6. The total laboratory solution: a new laboratory E-business model based on a vertical laboratory meta-network.

    Science.gov (United States)

    Friedman, B A

    2001-08-01

    Major forces are now reshaping all businesses on a global basis, including the healthcare and clinical laboratory industries. One of the major forces at work is information technology (IT), which now provides the opportunity to create a new economic and business model for the clinical laboratory industry based on the creation of an integrated vertical meta-network, referred to here as the "total laboratory solution" (TLS). Participants at the most basic level of such a network would include a hospital-based laboratory, a reference laboratory, a laboratory information system/application service provider/laboratory portal vendor, an in vitro diagnostic manufacturer, and a pharmaceutical/biotechnology manufacturer. It is suggested that each of these participants would add value to the network primarily in its area of core competency. Subvariants of such a network have evolved over recent years, but a TLS comprising all or most of these participants does not exist at this time. Although the TLS, enabled by IT and closely akin to the various e-businesses that are now taking shape, offers many advantages from a theoretical perspective over the current laboratory business model, its success will depend largely on (a) market forces, (b) how the collaborative networks are organized and managed, and (c) whether the network can offer healthcare organizations higher quality testing services at lower cost. If the concept is successful, new demands will be placed on hospital-based laboratory professionals to shift the range of professional services that they offer toward clinical consulting, integration of laboratory information from multiple sources, and laboratory information management. These information management and integration tasks can only increase in complexity in the future as new genomic and proteomics testing modalities are developed and come on-line in clinical laboratories.

  7. Program package for constructing analytical models of industrial robots

    Energy Technology Data Exchange (ETDEWEB)

    Vukobratovich, M.; Kirchanskiy, N.

    Complex multidimensional nonlinear dynamic systems are controlled with the use of control computers differing in their complexity, from large ones at the level of the modeling of the dynamics of the system and synthesis of the control algorithm to microcomputers directly controlling the system. One of the main decisive problems in controlling an industrial robot is the generation of a dynamic on-line model. For this purpose, a separate microcomputer or several computers operating in the multiprocessor mode are used. The existing methods of robot dynamics simulation which are based on the equations of Newton-Euler, Lagrange and others require a large number of numerical operations and they cannot be realized in real time: the time spent on the construction of a model is several times greater than that acceptable for the computer. This is explained by the following factors: complexity of the mathematical model, the use of a high-level language for programming, the desire to construct an algorithm of a general kind, which leads to high redundancy of numerical operations; the use of recursion relations, which excludes the possibility of performing parallel operations during the realization in a computer. Special characteristics of the construction of a program system which is to a considerable degree free of the above drawbacks is considered below. Instead of directly constructing a model in the numerical form on the basis of one of the approaches of classical mechanics, the concept of constructing a model in symbols is proposed here. It is possible to show that in this way it is possible to obtain a compact mathematical model which requires fewer numerical operations (multiplication, addition) for its realization by two orders in comparison with the methods used earlier. 9 references, 2 tables.

  8. Inferring 3D Articulated Models for Box Packaging Robot

    CERN Document Server

    Yang, Heran; Cong, Matthew; Saxena, Ashutosh

    2011-01-01

    Given a point cloud, we consider inferring kinematic models of 3D articulated objects such as boxes for the purpose of manipulating them. While previous work has shown how to extract a planar kinematic model (often represented as a linear chain), such planar models do not apply to 3D objects that are composed of segments often linked to the other segments in cyclic configurations. We present an approach for building a model that captures the relation between the input point cloud features and the object segment as well as the relation between the neighboring object segments. We use a conditional random field that allows us to model the dependencies between different segments of the object. We test our approach on inferring the kinematic structure from partial and noisy point cloud data for a wide variety of boxes including cake boxes, pizza boxes, and cardboard cartons of several sizes. The inferred structure enables our robot to successfully close these boxes by manipulating the flaps.

  9. bspmma: An R Package for Bayesian Semiparametric Models for Meta-Analysis

    Directory of Open Access Journals (Sweden)

    Deborah Burr

    2012-07-01

    Full Text Available We introduce an R package, bspmma, which implements a Dirichlet-based random effects model specific to meta-analysis. In meta-analysis, when combining effect estimates from several heterogeneous studies, it is common to use a random-effects model. The usual frequentist or Bayesian models specify a normal distribution for the true effects. However, in many situations, the effect distribution is not normal, e.g., it can have thick tails, be skewed, or be multi-modal. A Bayesian nonparametric model based on mixtures of Dirichlet process priors has been proposed in the literature, for the purpose of accommodating the non-normality. We review this model and then describe a competitor, a semiparametric version which has the feature that it allows for a well-defined centrality parameter convenient for determining whether the overall effect is significant. This second Bayesian model is based on a different version of the Dirichlet process prior, and we call it the "conditional Dirichlet model". The package contains functions to carry out analyses based on either the ordinary or the conditional Dirichlet model, functions for calculating certain Bayes factors that provide a check on the appropriateness of the conditional Dirichlet model, and functions that enable an empirical Bayes selection of the precision parameter of the Dirichlet process. We illustrate the use of the package on two examples, and give an interpretation of the results in these two different scenarios.

  10. A modular approach for item response theory modeling with the R package flirt.

    Science.gov (United States)

    Jeon, Minjeong; Rijmen, Frank

    2016-06-01

    The new R package flirt is introduced for flexible item response theory (IRT) modeling of psychological, educational, and behavior assessment data. flirt integrates a generalized linear and nonlinear mixed modeling framework with graphical model theory. The graphical model framework allows for efficient maximum likelihood estimation. The key feature of flirt is its modular approach to facilitate convenient and flexible model specifications. Researchers can construct customized IRT models by simply selecting various modeling modules, such as parametric forms, number of dimensions, item and person covariates, person groups, link functions, etc. In this paper, we describe major features of flirt and provide examples to illustrate how flirt works in practice.

  11. Unified Geostatistical Modeling for Data Fusion and Spatial Heteroskedasticity with R Package ramps

    Directory of Open Access Journals (Sweden)

    Brian J. Smith

    2008-03-01

    Full Text Available This article illustrates usage of the ramps R package, which implements the reparameterized and marginalized posterior sampling (RAMPS algorithm for complex Bayesian geostatistical models. The RAMPS methodology allows joint modeling of areal and point-source data arising from the same underlying spatial process. A reparametrization of variance parameters facilitates slice sampling based on simplexes, which can be useful in general when multiple variances are present. Prediction at arbitrary points can be made, which is critical in applications where maps are needed. Our implementation takes advantage of sparse matrix operations in the Matrix package and can provide substantial savings in computing time for large datasets. A user-friendly interface, similar to the nlme mixed effects models package, enables users to analyze datasets with little programming effort. Support is provided for numerous spatial and spatiotemporal correlation structures, user-defined correlation structures, and non-spatial random effects. The package features are illustrated via a synthetic dataset of spatially correlated observation distributed across the state of Iowa, USA.

  12. A professional development model for medical laboratory scientists working in the immunohematology laboratory.

    Science.gov (United States)

    Garza, Melinda N; Pulido, Lila A; Amerson, Megan; Ali, Faheem A; Greenhill, Brandy A; Griffin, Gary; Alvarez, Enrique; Whatley, Marsha; Hu, Peter C

    2012-01-01

    Transfusion medicine, a section of the Department of Laboratory Medicine at The University of Texas MD Anderson Cancer Center is committed to the education and advancement of its health care professionals. It is our belief that giving medical laboratory professionals a path for advancement leads to excellence and increases overall professionalism in the Immunohematology Laboratory. As a result of this strong commitment to excellence and professionalism, the Immunohematology laboratory has instituted a Professional Development Model (PDM) that aims to create Medical Laboratory Scientists (MLS) that are not only more knowledgeable, but are continually striving for excellence. In addition, these MLS are poised for advancement in their careers. The professional development model consists of four levels: Discovery, Application, Maturation, and Expert. The model was formulated to serve as a detailed path to the mastery of all process and methods in the Immunohematology Laboratory. Each level in the professional development model consists of tasks that optimize the laboratory workflow and allow for concurrent training. Completion of a level in the PDM is rewarded with financial incentive and further advancement in the field. The PDM for Medical Laboratory Scientists in the Immunohematology Laboratory fosters personal development, rewards growth and competency, and sets high standards for all services and skills provided. This model is a vital component of the Immunohematology Laboratory and aims to ensure the highest quality of care and standards in their testing. It is because of the success of this model and the robustness of its content that we hope other medical laboratories aim to reach the same level of excellence and professionalism, and adapt this model into their own environment.

  13. Estimating the Multilevel Rasch Model: With the lme4 Package

    Directory of Open Access Journals (Sweden)

    Harold Doran

    2007-02-01

    Full Text Available Traditional Rasch estimation of the item and student parameters via marginal maximum likelihood, joint maximum likelihood or conditional maximum likelihood, assume individuals in clustered settings are uncorrelated and items within a test that share a grouping structure are also uncorrelated. These assumptions are often violated, particularly in educational testing situations, in which students are grouped into classrooms and many test items share a common grouping structure, such as a content strand or a reading passage. Consequently, one possible approach is to explicitly recognize the clustered nature of the data and directly incorporate random effects to account for the various dependencies. This article demonstrates how the multilevel Rasch model can be estimated using the functions in R for mixed-effects models with crossed or partially crossed random effects. We demonstrate how to model the following hierarchical data structures: a individuals clustered in similar settings (e.g., classrooms, schools, b items nested within a particular group (such as a content strand or a reading passage, and c how to estimate a teacher × content strand interaction.

  14. DEMONSTRATION OF EQUIVALENCY OF CANE AND SOFTWOOD BASED CELOTEX FOR MODEL 9975 SHIPPING PACKAGES

    Energy Technology Data Exchange (ETDEWEB)

    Watkins, R; Jason Varble, J

    2008-05-27

    Cane-based Celotex{trademark} has been used extensively in various Department of Energy (DOE) packages as a thermal insulator and impact absorber. Cane-based Celotex{trademark} fiberboard was only manufactured by Knight-Celotex Fiberboard at their Marrero Plant in Louisiana. However, Knight-Celotex Fiberboard shut down their Marrero Plant in early 2007 due to impacts from hurricane Katrina and other economic factors. Therefore, cane-based Celotex{trademark} fiberboard is no longer available for use in the manufacture of new shipping packages requiring the material as a component. Current consolidation plans for the DOE Complex require the procurement of several thousand new Model 9975 shipping packages requiring cane-based Celotex{trademark} fiberboard. Therefore, an alternative to cane-based Celotex{trademark} fiberboard is needed. Knight-Celotex currently manufactures Celotex{trademark} fiberboard from other cellulosic materials, such as hardwood and softwood. A review of the relevant literature has shown that softwood-based Celotex{trademark} meets all parameters important to the Model 9975 shipping package.

  15. The Computer-Aided Analytic Process Model. Operations Handbook for the APM (Analytic Process Model) Demonstration Package. Appendix

    Science.gov (United States)

    1986-01-01

    The Analytic Process Model for System Design and Measurement: A Computer-Aided Tool for Analyzing Training Systems and Other Human-Machine Systems. A...separate companion volume--The Computer-Aided Analytic Process Model : Operations Handbook for the APM Demonstration Package is also available under

  16. Estimating Population Abundance Using Sightability Models: R SightabilityModel Package

    Directory of Open Access Journals (Sweden)

    John R. Fieberg

    2012-11-01

    Full Text Available Sightability models are binary logistic-regression models used to estimate and adjust for visibility bias in wildlife-population surveys (Steinhorst and Samuel 1989. Estimation proceeds in 2 stages: (1 Sightability trials are conducted with marked individuals, and logistic regression is used to estimate the probability of detection as a function of available covariates (e.g., visual obstruction, group size. (2 The fitted model is used to adjust counts (from future surveys for animals that were not observed. A modified Horvitz-Thompson estimator is used to estimate abundance: counts of observed animal groups are divided by their inclusion probabilites (determined by plot-level sampling probabilities and the detection probabilities estimated from stage 1. We provide a brief historical account of the approach, clarifying and documenting suggested modifications to the variance estimators originally proposed by Steinhorst and Samuel (1989. We then introduce a new R package, SightabilityModel, for estimating abundance using this technique. Lastly, we illustrate the software with a series of examples using data collected from moose (Alces alces in northeastern Minnesota and mountain goats (Oreamnos americanus in Washington State.

  17. A two-dimensional simulation model for the molded underfill process in flip chip packaging

    Energy Technology Data Exchange (ETDEWEB)

    Guo, Xue Ru; Young, Wen Bin [National Cheng Kung University, Tainan (China)

    2015-07-15

    The flip chip process involves the deposition of solder bumps on the chip surface and their subsequent direct attachment and connection to a substrate. Underfilling traditional flip chip packaging is typically performed following a two-step approach. The first step uses capillary force to fill the gap between the chip and the substrate, and the second step uses epoxy molding compound (EMC) to overmold the package. Unlike traditional flip chip packaging, the molded underfill (MUF) concept uses a single-step approach to simultaneously achieve both underfill and overmold. MUF is a simpler and faster process. In this study, a 2D numerical model is developed to simulate the front movement of EMC flow and the void formation for different geometric parameters. The 2D model simplifies the procedures of geometric modeling and reduces the modeling time for the MUF simulation. Experiments are conducted to verify the prediction results of the model. The effect on void formation for different geometric parameters is investigated using a 2D model.

  18. Distributed Lag Linear and Non-Linear Models in R: The Package dlnm

    Directory of Open Access Journals (Sweden)

    Antonio Gasparrini

    2011-08-01

    Full Text Available Distributed lag non-linear models (DLNMs represent a modeling framework to flexibly describe associations showing potentially non-linear and delayed effects in time series data. This methodology rests on the definition of a crossbasis, a bi-dimensional functional space expressed by the combination of two sets of basis functions, which specify the relationships in the dimensions of predictor and lags, respectively. This framework is implemented in the R package dlnm, which provides functions to perform the broad range of models within the DLNM family and then to help interpret the results, with an emphasis on graphical representation. This paper offers an overview of the capabilities of the package, describing the conceptual and practical steps to specify and interpret DLNMs with an example of application to real data.

  19. Introducing COZIGAM: An R Package for Unconstrained and Constrained Zero-Inflated Generalized Additive Model Analysis

    Directory of Open Access Journals (Sweden)

    Hai Liu

    2010-10-01

    Full Text Available Zero-inflation problem is very common in ecological studies as well as other areas. Nonparametric regression with zero-inflated data may be studied via the zero-inflated generalized additive model (ZIGAM, which assumes that the zero-inflated responses come from a probabilistic mixture of zero and a regular component whose distribution belongs to the 1-parameter exponential family. With the further assumption that the probability of non-zero-inflation is some monotonic function of the mean of the regular component, we propose the constrained zero-inflated generalized additive model (COZIGAM for analyzingzero-inflated data. When the hypothesized constraint obtains, the new approach provides a unified framework for modeling zero-inflated data, which is more parsimonious and efficient than the unconstrained ZIGAM. We have developed an R package COZIGAM which contains functions that implement an iterative algorithm for fitting ZIGAMs and COZIGAMs to zero-inflated data basedon the penalized likelihood approach. Other functions included in the package are useful for model prediction and model selection. We demonstrate the use of the COZIGAM package via some simulation studies and a real application.

  20. XCAT/DRASIM: a realistic CT/human-model simulation package

    Science.gov (United States)

    Fung, George S. K.; Stierstorfer, Karl; Segars, W. Paul; Taguchi, Katsuyuki; Flohr, Thomas G.; Tsui, Benjamin M. W.

    2011-03-01

    The aim of this research is to develop a complete CT/human-model simulation package by integrating the 4D eXtended CArdiac-Torso (XCAT) phantom, a computer generated NURBS surface based phantom that provides a realistic model of human anatomy and respiratory and cardiac motions, and the DRASIM (Siemens Healthcare) CT-data simulation program. Unlike other CT simulation tools which are based on simple mathematical primitives or voxelized phantoms, this new simulation package has the advantages of utilizing a realistic model of human anatomy and physiological motions without voxelization and with accurate modeling of the characteristics of clinical Siemens CT systems. First, we incorporated the 4D XCAT anatomy and motion models into DRASIM by implementing a new library which consists of functions to read-in the NURBS surfaces of anatomical objects and their overlapping order and material properties in the XCAT phantom. Second, we incorporated an efficient ray-tracing algorithm for line integral calculation in DRASIM by computing the intersection points of the rays cast from the x-ray source to the detector elements through the NURBS surfaces of the multiple XCAT anatomical objects along the ray paths. Third, we evaluated the integrated simulation package by performing a number of sample simulations of multiple x-ray projections from different views followed by image reconstruction. The initial simulation results were found to be promising by qualitative evaluation. In conclusion, we have developed a unique CT/human-model simulation package which has great potential as a tool in the design and optimization of CT scanners, and the development of scanning protocols and image reconstruction methods for improving CT image quality and reducing radiation dose.

  1. Safety evaluation for packaging (onsite) for the concrete-shielded RH TRU drum for the 327 Postirradiation Testing Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Smith, R.J.

    1998-03-31

    This safety evaluation for packaging authorizes onsite transport of Type B quantities of radioactive material in the Concrete Shielded Remote-Handled Transuranic Waste (RH TRU) Drum per HNF-PRO-154, Responsibilities and Procedures for all Hazardous Material Shipments. The drum will be used for transport of 327 Building legacy waste from the 300 Area to a solid waste storage facility on the Hanford Site.

  2. An Integrated Biochemistry Laboratory, Including Molecular Modeling

    Science.gov (United States)

    Hall, Adele J. Wolfson Mona L.; Branham, Thomas R.

    1996-11-01

    ) experience with methods of protein purification; (iii) incorporation of appropriate controls into experiments; (iv) use of basic statistics in data analysis; (v) writing papers and grant proposals in accepted scientific style; (vi) peer review; (vii) oral presentation of results and proposals; and (viii) introduction to molecular modeling. Figure 1 illustrates the modular nature of the lab curriculum. Elements from each of the exercises can be separated and treated as stand-alone exercises, or combined into short or long projects. We have been able to offer the opportunity to use sophisticated molecular modeling in the final module through funding from an NSF-ILI grant. However, many of the benefits of the research proposal can be achieved with other computer programs, or even by literature survey alone. Figure 1.Design of project-based biochemistry laboratory. Modules (projects, or portions of projects) are indicated as boxes. Each of these can be treated independently, or used as part of a larger project. Solid lines indicate some suggested paths from one module to the next. The skills and knowledge required for protein purification and design are developed in three units: (i) an introduction to critical assays needed to monitor degree of purification, including an evaluation of assay parameters; (ii) partial purification by ion-exchange techniques; and (iii) preparation of a grant proposal on protein design by mutagenesis. Brief descriptions of each of these units follow, with experimental details of each project at the end of this paper. Assays for Lysozyme Activity and Protein Concentration (4 weeks) The assays mastered during the first unit are a necessary tool for determining the purity of the enzyme during the second unit on purification by ion exchange. These assays allow an introduction to the concept of specific activity (units of enzyme activity per milligram of total protein) as a measure of purity. In this first sequence, students learn a turbidimetric assay

  3. Hidden Semi Markov Models for Multiple Observation Sequences: The mhsmm Package for R

    DEFF Research Database (Denmark)

    O'Connell, Jarad Michael; Højsgaard, Søren

    2011-01-01

    This paper describes the R package mhsmm which implements estimation and prediction methods for hidden Markov and semi-Markov models for multiple observation sequences. Such techniques are of interest when observed data is thought to be dependent on some unobserved (or hidden) state. Hidden Markov...... models only allow a geometrically distributed sojourn time in a given state, while hidden semi-Markov models extend this by allowing an arbitrary sojourn distribution. We demonstrate the software with simulation examples and an application involving the modelling of the ovarian cycle of dairy cows...

  4. metaSEM: an R package for meta-analysis using structural equation modeling.

    Science.gov (United States)

    Cheung, Mike W-L

    2014-01-01

    The metaSEM package provides functions to conduct univariate, multivariate, and three-level meta-analyses using a structural equation modeling (SEM) approach via the OpenMx package in the R statistical platform. It also implements the two-stage SEM approach to conducting fixed- and random-effects meta-analytic SEM on correlation or covariance matrices. This paper briefly outlines the theories and their implementations. It provides a summary on how meta-analyses can be formulated as structural equation models. The paper closes with a conclusion on several relevant topics to this SEM-based meta-analysis. Several examples are used to illustrate the procedures in the supplementary material.

  5. Implementing a Simulation Study Using Multiple Software Packages for Structural Equation Modeling

    Directory of Open Access Journals (Sweden)

    Sunbok Lee

    2015-07-01

    Full Text Available A Monte Carlo simulation study is an essential tool for evaluating the behavior of various quantitative methods including structural equation modeling (SEM under various conditions. Typically, a large number of replications are recommended for a Monte Carlo simulation study, and therefore automating a Monte Carlo simulation study is important to get the desired number of replications for a simulation study. This article is intended to provide concrete examples for automating a Monte Carlo simulation study using some standard software packages for SEM: Mplus, LISREL, SAS PROC CALIS, and R package lavaan. Also, the equivalence between the multilevel SEM and hierarchical linear modeling (HLM is discussed, and relevant examples are provided. It is hoped that the codes in this article can provide some building blocks for researchers to write their own code to automate simulation procedures.

  6. Flow Through a Laboratory Sediment Sample by Computer Simulation Modeling

    Science.gov (United States)

    2006-09-07

    Flow through a laboratory sediment sample by computer simulation modeling R.B. Pandeya’b*, Allen H. Reeda, Edward Braithwaitea, Ray Seyfarth0, J.F...through a laboratory sediment sample by computer simulation modeling 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S

  7. An Elastic Plastic Contact Model with Strain Hardening for the LAMMPS Granular Package

    Energy Technology Data Exchange (ETDEWEB)

    Kuhr, Bryan [Virginia Polytechnic Inst. and State Univ. (Virginia Tech), Blacksburg, VA (United States); Brake, Matthew Robert [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Component Science and Mechanics; Lechman, Jeremy B. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Nanoscale and Reactive Processes

    2015-03-01

    The following details the implementation of an analytical elastic plastic contact model with strain hardening for normal im pacts into the LAMMPS granular package. The model assumes that, upon impact, the co llision has a period of elastic loading followed by a period of mixed elastic plas tic loading, with contributions to each mechanism estimated by a hyperbolic seca nt weight function. This function is implemented in the LAMMPS source code as the pair style gran/ep/history. Preliminary tests, simulating the pouring of pure nickel spheres, showed the elastic/plastic model took 1.66x as long as similar runs using gran/hertz/history.

  8. CASE ANALYSIS OF INNOVATION IN THE PACKAGING INDUSTRY USING THE CYCLIC INNOVATION MODEL

    OpenAIRE

    Ford, Nicholas; Trott, Paul; Simms, Chris; Hartmann, Dap

    2014-01-01

    This paper builds upon Berkhout et al.’s (2010) cyclic innovation model (CIM). This model was shown to provide an effective framework for understanding and managing the innovation process and to address many of the shortcomings of previous models. Building on that article we have applied CIM to an in-depth case study featuring a formable paperboard technology within the packaging industry. Using data gathered from 28 interviews conducted over a three year period, CIM, for the first time, is a...

  9. Numerical modeling and validation of squeezed-film damping in vacuum-packaged industrial MEMS

    Science.gov (United States)

    Syed, Wajih U.; Brimmo, Ayoola; Waheed, Owais; Bojesomo, Alabi; Hassan Ali, Mohamed; Ocak, Ilker; Chengliang, Sun; Chatterjee, Aveek; Elfadel, Ibrahim (Abe M.

    2017-07-01

    Several high-performance, industrial micro-electromechanical (MEM) devices, such as gyroscopes, magnetometers, high-Q resonators and piezoelectric energy harvesters, require wafer bonding and packaging under near-vacuum conditions. One very challenging aspect of the design, verification and characterisation of these devices is to predict their performance characteristics in the presence of any residual gases post-packaging. Such gases contribute to the energy losses resulting from device surfaces squeezing or sliding against the gas films within the device cavities. In this paper, we fully expose the modelling assumptions used in commercial FEM tools to estimate the squeezed-film damping (SFD) experienced by MEM devices that are packaged under near-vacuum conditions. We also explain the various meshing options to enable the extraction of the most accurate Q factors under existing SFD assumptions. In addition, we compare the computational results across a variety of commercial FEM codes against measurements obtained under realistic vacuum conditions for an industrial high-Q magnetometer. These measurements suggest that existing computational models may deviate by as much as 25% on Q factor values for gas flow regimes under operating cavity pressures of less than 1 Torr.

  10. Radiative transfer modeling through terrestrial atmosphere and ocean accounting for inelastic processes: Software package SCIATRAN

    Science.gov (United States)

    Rozanov, V. V.; Dinter, T.; Rozanov, A. V.; Wolanin, A.; Bracher, A.; Burrows, J. P.

    2017-06-01

    SCIATRAN is a comprehensive software package which is designed to model radiative transfer processes in the terrestrial atmosphere and ocean in the spectral range from the ultraviolet to the thermal infrared (0.18-40 μm). It accounts for multiple scattering processes, polarization, thermal emission and ocean-atmosphere coupling. The main goal of this paper is to present a recently developed version of SCIATRAN which takes into account accurately inelastic radiative processes in both the atmosphere and the ocean. In the scalar version of the coupled ocean-atmosphere radiative transfer solver presented by Rozanov et al. [61] we have implemented the simulation of the rotational Raman scattering, vibrational Raman scattering, chlorophyll and colored dissolved organic matter fluorescence. In this paper we discuss and explain the numerical methods used in SCIATRAN to solve the scalar radiative transfer equation including trans-spectral processes, and demonstrate how some selected radiative transfer problems are solved using the SCIATRAN package. In addition we present selected comparisons of SCIATRAN simulations with those published benchmark results, independent radiative transfer models, and various measurements from satellite, ground-based, and ship-borne instruments. The extended SCIATRAN software package along with a detailed User's Guide is made available for scientists and students, who are undertaking their own research typically at universities, via the web page of the Institute of Environmental Physics (IUP), University of Bremen: http://www.iup.physik.uni-bremen.de.

  11. strucchange: An R Package for Testing for Structural Change in Linear Regression Models

    Directory of Open Access Journals (Sweden)

    Achim Zeileis

    2002-01-01

    Full Text Available This paper reviews tests for structural change in linear regression models from the generalized fluctuation test framework as well as from the F test (Chow test framework. It introduces a unified approach for implementing these tests and presents how these ideas have been realized in an R package called strucchange. Enhancing the standard significance test approach the package contains methods to fit, plot and test empirical fluctuation processes (like CUSUM, MOSUM and estimates-based processes and to compute, plot and test sequences of F statistics with the supF , aveF and expF test. Thus, it makes powerful tools available to display information about structural changes in regression relationships and to assess their significance. Furthermore, it is described how incoming data can be monitored.

  12. Application of Tube-Packaged FBG Strain Sensor in Vibration Experiment of Submarine Pipeline Model

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Optical fiber sensors have received increasing attention in the fields of aeronautic and civil engineering for their superior ability to stand explosion, immunity to electromagnetic interference and high accuracy, especially fit for measurement applications in harsh environment. In this study, a novel FBG (fiber Bragg grating) strain sensor, which is packaged in a 1.2 mm stainless steel tube with epoxy resin, is developed. Experiments are conducted on the universal material testing machine to calibrate its strain transferring characteristics. The sensor has the advantages of small size, high precision and flexible use, and exhibits promising potentials. Five tube-packaged strain FBG sensors have been applied to the vibration experiment of a submarine pipeline model. The strain measured with the FBG sensor agrees well with that measured with the electric resistance strain sensor.

  13. Groundwater flow and solute transport modelling from within R: Development of the RMODFLOW and RMT3DMS packages.

    Science.gov (United States)

    Rogiers, Bart

    2015-04-01

    Since a few years, an increasing number of contributed R packages is becoming available, in the field of hydrology. Hydrological time series analysis packages, lumped conceptual rainfall-runoff models, distributed hydrological models, weather generators, and different calibration and uncertainty estimation methods are all available. Also a few packages are available for solving partial differential equations. Subsurface hydrological modelling is however still seldomly performed in R, or with codes interfaced with R, despite the fact that excellent geostatistical packages, model calibration/inversion options and state-of-the-art visualization libraries are available. Moreover, other popular scientific programming languages like matlab and python have packages for pre- and post-processing files of MODFLOW (Harbaugh 2005) and MT3DMS (Zheng 2010) models. To fill this gap, we present here the development versions of the RMODFLOW and RMT3DMS packages, which allow pre- and post-processing MODFLOW and MT3DMS input and output files from within R. File reading and writing functions are currently available for different packages, and plotting functions are foreseen making use of the ggplot2 package (plotting system based on the grammar of graphics; Wickham 2009). The S3 generic-function object oriented programming style is used for this. An example is provided, making modifications to an existing model, and visualization of the model output. References Harbaugh, A. (2005). MODFLOW-2005: The US Geological Survey Modular Ground-water Model--the Ground-water Flow Process, U.S. Geological Survey Techniques and Methods 6-A16 (p. 253). Wickham, H. (2009). ggplot2: elegant graphics for data analysis. Springer New York, 2009. Zheng, C. (2010). MT3DMS v5.3, a modular three-dimensional multispecies transport model for simulation of advection, dispersion and chemical reactions of contaminants in groundwater systems. Supplemental User's Guide. (p. 56).

  14. msSurv: An R Package for Nonparametric Estimation of Multistate Models

    Directory of Open Access Journals (Sweden)

    Nicole Ferguson

    2012-09-01

    Full Text Available We present an R package, msSurv, to calculate the marginal (that is, not conditional on any covariates state occupation probabilities, the state entry and exit time distributions, and the marginal integrated transition hazard for a general, possibly non-Markov, multistate system under left-truncation and right censoring. For a Markov model, msSurv also calculates and returns the transition probability matrix between any two states. Dependent censoring is handled via modeling the censoring hazard through observable covariates. Pointwise confidence intervals for the above mentioned quantities are obtained and returned for independent censoring from closed-form variance estimators and for dependent censoring using the bootstrap.

  15. Linear Quantile Mixed Models: The lqmm Package for Laplace Quantile Regression

    Directory of Open Access Journals (Sweden)

    Marco Geraci

    2014-05-01

    Full Text Available Inference in quantile analysis has received considerable attention in the recent years. Linear quantile mixed models (Geraci and Bottai 2014 represent a ?exible statistical tool to analyze data from sampling designs such as multilevel, spatial, panel or longitudinal, which induce some form of clustering. In this paper, I will show how to estimate conditional quantile functions with random e?ects using the R package lqmm. Modeling, estimation and inference are discussed in detail using a real data example. A thorough description of the optimization algorithms is also provided.

  16. ATLAS software packaging

    Science.gov (United States)

    Rybkin, Grigory

    2012-12-01

    Software packaging is indispensable part of build and prerequisite for deployment processes. Full ATLAS software stack consists of TDAQ, HLT, and Offline software. These software groups depend on some 80 external software packages. We present tools, package PackDist, developed and used to package all this software except for TDAQ project. PackDist is based on and driven by CMT, ATLAS software configuration and build tool, and consists of shell and Python scripts. The packaging unit used is CMT project. Each CMT project is packaged as several packages—platform dependent (one per platform available), source code excluding header files, other platform independent files, documentation, and debug information packages (the last two being built optionally). Packaging can be done recursively to package all the dependencies. The whole set of packages for one software release, distribution kit, also includes configuration packages and contains some 120 packages for one platform. Also packaged are physics analysis projects (currently 6) used by particular physics groups on top of the full release. The tools provide an installation test for the full distribution kit. Packaging is done in two formats for use with the Pacman and RPM package managers. The tools are functional on the platforms supported by ATLAS—GNU/Linux and Mac OS X. The packaged software is used for software deployment on all ATLAS computing resources from the detector and trigger computing farms, collaboration laboratories computing centres, grid sites, to physicist laptops, and CERN VMFS and covers the use cases of running all applications as well as of software development.

  17. Modeling of Stress Corrosion Cracking for High Level Radioactive-Waste Packages

    Energy Technology Data Exchange (ETDEWEB)

    Lu, S C; Gordon, G M; Andresen, P L; Herrera, M L

    2003-06-20

    A stress corrosion cracking (SCC) model has been adapted for performance prediction of high level radioactive-waste packages to be emplaced in the proposed Yucca Mountain radioactive-waste repository. SCC is one form of environmentally assisted cracking due to three factors, which must be present simultaneously: metallurgical susceptibility, critical environment, and static (or sustained) tensile stresses. For waste packages of the proposed Yucca Mountain repository, the outer barrier material is Alloy 22, a highly corrosion resistant alloy, the environment is represented by the water film present on the surface of the waste package from dripping or deliquescence of soluble salts present in any surface deposits, and the stress is principally the weld induced residual stress. SCC has historically been separated into ''initiation'' and ''propagation'' phases. Initiation of SCC will not occur on a smooth surface if the surface stress is below a threshold value defined as the threshold stress. Cracks can also initiate at and propagate from flaws (or defects) resulting from manufacturing processes (such as welding). To account for crack propagation, the slip dissolution/film rupture (SDFR) model is adopted to provide mathematical formulas for prediction of the crack growth rate. Once the crack growth rate at an initiated SCC is determined, the time to through-wall penetration for the waste package can be calculated. The SDFR model relates the advance (or propagation) of cracks, subsequent to the crack initiation from bare metal surface, to the metal oxidation transients that occur when the protective film at the crack tip is continually ruptured and repassivated. A crack, however, may reach the ''arrest'' state before it enters the ''propagation'' phase. There exists a threshold stress intensity factor, which provides a criterion for determining if an initiated crack or pre

  18. Performance Evaluation of O-Ring Seals in Model 9975 Packaging Assemblies (U)

    Energy Technology Data Exchange (ETDEWEB)

    Skidmore, Eric

    1998-12-28

    The Materials Consultation Group of SRTC has completed a review of existing literature and data regarding the useable service life of Viton{reg_sign} GLT fluoroelastomer O-rings currently used in the Model 9975 packaging assemblies. Although the shipping and transportation period is normally limited to 2 years, it is anticipated that these packages will be used for longer-term storage of Pu-bearing materials in KAMS (K-Area Materials Storage) prior to processing or disposition in the APSF (Actinide Packaging and Storage Facility). Based on the service conditions and review of available literature, Materials Consultation concludes that there is sufficient existing data to establish the technical basis for storage of Pu-bearing materials using Parker Seals O-ring compound V835-75 (or equivalent) for up to 10 years following the 2-year shipping period. Although significant physical deterioration of the O-rings and release of product is not expected, definite changes in physical properties will occur. However, due to the complex relationship between elastomer formulation, seal properties, and competing degradation mechanisms, the actual degree of property variation and impact upon seal performance is difficult to predict. Therefore, accelerated aging and/or surveillance programs are recommended to validate the assumptions outlined in this report and to assess the long-term performance of O-ring seals under actual service conditions. Such programs could provide a unique opportunity to develop nonexistent long-term performance data, as well as address storage extension issues if necessary.

  19. DBSolve Optimum: a software package for kinetic modeling which allows dynamic visualization of simulation results

    Directory of Open Access Journals (Sweden)

    Gizzatkulov Nail M

    2010-08-01

    Full Text Available Abstract Background Systems biology research and applications require creation, validation, extensive usage of mathematical models and visualization of simulation results by end-users. Our goal is to develop novel method for visualization of simulation results and implement it in simulation software package equipped with the sophisticated mathematical and computational techniques for model development, verification and parameter fitting. Results We present mathematical simulation workbench DBSolve Optimum which is significantly improved and extended successor of well known simulation software DBSolve5. Concept of "dynamic visualization" of simulation results has been developed and implemented in DBSolve Optimum. In framework of the concept graphical objects representing metabolite concentrations and reactions change their volume and shape in accordance to simulation results. This technique is applied to visualize both kinetic response of the model and dependence of its steady state on parameter. The use of the dynamic visualization is illustrated with kinetic model of the Krebs cycle. Conclusion DBSolve Optimum is a user friendly simulation software package that enables to simplify the construction, verification, analysis and visualization of kinetic models. Dynamic visualization tool implemented in the software allows user to animate simulation results and, thereby, present them in more comprehensible mode. DBSolve Optimum and built-in dynamic visualization module is free for both academic and commercial use. It can be downloaded directly from http://www.insysbio.ru.

  20. A new vector radiative transfer model as a part of SCIATRAN 3.0 software package.

    Science.gov (United States)

    Rozanov, Alexei; Rozanov, Vladimir; Burrows, John P.

    The SCIATRAN 3.0 package is a result of further development of the SCIATRAN 2.x software family which, similar to previous versions, comprises a radiative transfer model and a retrieval block. A major improvement was achieved in comparison to previous software versions by adding the vector mode to the radiative transfer model. Thus, the well-established Discrete Ordinate solver can now be run in the vector mode to calculate the scattered solar radiation including polarization, i.e., to simulate all four components of the Stockes vector. Similar to the scalar version, the simulations can be performed for any viewing geometry typical for atmospheric observations in the UV-Vis-NIR spectral range (nadir, limb, off-axis, etc.) as well as for any observer position within or outside the Earth's atmosphere. Similar to the precursor version, the new model is freely available for non-commercial use via the web page of the University of Bremen. In this presentation a short description of the software package, especially of the new vector radiative transfer model will be given, including remarks on the availability for the scientific community. Furthermore, comparisons to other vector models will be shown and some example problems will be considered where the polarization of the observed radiation must be accounted for to obtain high quality results.

  1. An Early Childhood Movement Laboratory Model: Kindergym

    Science.gov (United States)

    Marston, Rip

    2004-01-01

    Early childhood motor activity programs at institutions of higher learning can operate within the tripartite mission of the university while serving a vital function in providing leadership and guidance to educators. This article describes the University of Northern Iowa's Kindergym model. Within this model, curricular areas of games/sports,…

  2. Simulation-based Bayesian inference for latent traits of item response models: Introduction to the ltbayes package for R.

    Science.gov (United States)

    Johnson, Timothy R; Kuhn, Kristine M

    2015-12-01

    This paper introduces the ltbayes package for R. This package includes a suite of functions for investigating the posterior distribution of latent traits of item response models. These include functions for simulating realizations from the posterior distribution, profiling the posterior density or likelihood function, calculation of posterior modes or means, Fisher information functions and observed information, and profile likelihood confidence intervals. Inferences can be based on individual response patterns or sets of response patterns such as sum scores. Functions are included for several common binary and polytomous item response models, but the package can also be used with user-specified models. This paper introduces some background and motivation for the package, and includes several detailed examples of its use.

  3. RHEUMATOID ARTHRITIS: LABORATORY MODELS OF THE DISEASE

    Directory of Open Access Journals (Sweden)

    I. A. Orlovskaya

    2015-01-01

    Full Text Available The  establishment and  application of animal  models  represent effective  tools  for  research  in rheumatoid arthritis (RA pathogenesis. Animal models that replicate various mechanisms reflecting all aspects of RA, including early RA pathology, have provided important insights into studying etiology and pathogenetic mechanisms of RA in humans. This review article was compiled in order to give an introduction to the current state of RA models.  Application of these  experimental disorders  for testing  potential therapeutic approaches will help to make better predictions for drug efficiency in human RA

  4. Environmental and economic benefit of recycling model of packaging waste:a case study on aluminum

    Institute of Scientific and Technical Information of China (English)

    Huang Pingsha

    2004-01-01

    In order to achieve sustainable utilization of natural resources, save energy and protect environment and ecosystem, it is important for a region or a nation to develop and implement a viable waste recycling model from both theoretical and practical point of view. Some packaging recycling models operated in developed countries are introduced in this article. Aluminium can recovery and recycling is emphasized. Cost effective, economic and environmental benefit of different models are compared and analyzed. The result shows that all recycling models have their characteristics due to the initial purpose of recovery and the situation of the implementing country. However, all the models contribute to the reduction of municipal solid waste disposal and resources conservation.

  5. Laboratory models of Hawaiian and Strombolian eruptions

    Science.gov (United States)

    Jaupart, Claude; Vergniolle, Sylvie

    1988-01-01

    Basaltic eruptions are often characterized by cyclic changes of activity. At Hawaii, periods of continuous fountaining alternate with much longer periods of effusive outflow1,2. In Strombolian eruptions, activity proceeds through intermittent discrete bursts2-5. We report laboratory experiments that simulate the degassing process in basaltic eruptions. Gas bubbles are generated at the bottom of a tank filled with viscous liquid and topped by a small open conduit. The bubbles rise and accumulate at the roof in a foam layer whose thickness increases. At a critical thickness the bubbles coalesce and the foam collapses, generating gas pockets whose size depends on liquid viscosity and surface tension. At low viscosity a single large gas pocket is formed, which flows into the conduit. This erupts in an annular flow configuration where a central jet expels the liquid films that wet the conduit walls6. At higher viscosity many smaller pockets are formed, which rise as slugs and burst out intermittently at the vent. The experiments imply that the presence of constrictions in the chamber and conduits plays a major role in determining eruption behaviour.

  6. Modeling human influenza infection in the laboratory

    Directory of Open Access Journals (Sweden)

    Radigan KA

    2015-08-01

    Full Text Available Kathryn A Radigan,1 Alexander V Misharin,2 Monica Chi,1 GR Scott Budinger11Division of Pulmonary and Critical Care Medicine, 2Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USAAbstract: Influenza is the leading cause of death from an infectious cause. Because of its clinical importance, many investigators use animal models to understand the biologic mechanisms of influenza A virus replication, the immune response to the virus, and the efficacy of novel therapies. This review will focus on the biosafety, biosecurity, and ethical concerns that must be considered in pursuing influenza research, in addition to focusing on the two animal models – mice and ferrets – most frequently used by researchers as models of human influenza infection.Keywords: mice, ferret, influenza, animal model, biosafety

  7. Utilizing an Adaptive Grey Model for Short-Term Time Series Forecasting: A Case Study of Wafer-Level Packaging

    Directory of Open Access Journals (Sweden)

    Che-Jung Chang

    2013-01-01

    Full Text Available The wafer-level packaging process is an important technology used in semiconductor manufacturing, and how to effectively control this manufacturing system is thus an important issue for packaging firms. One way to aid in this process is to use a forecasting tool. However, the number of observations collected in the early stages of this process is usually too few to use with traditional forecasting techniques, and thus inaccurate results are obtained. One potential solution to this problem is the use of grey system theory, with its feature of small dataset modeling. This study thus uses the AGM(1,1 grey model to solve the problem of forecasting in the pilot run stage of the packaging process. The experimental results show that the grey approach is an appropriate and effective forecasting tool for use with small datasets and that it can be applied to improve the wafer-level packaging process.

  8. PyMT: A Python package for model-coupling in the Earth sciences

    Science.gov (United States)

    Hutton, E.

    2016-12-01

    The current landscape of Earth-system models is not only broad in scientific scope, but also broad in type. On the one hand, the large variety of models is exciting, as it provides fertile ground for extending or linking models together in novel ways to answer new scientific questions. However, the heterogeneity in model type acts to inhibit model coupling, model development, or even model use. Existing models are written in a variety of programming languages, operate on different grids, use their own file formats (both for input and output), have different user interfaces, have their own time steps, etc. Each of these factors become obstructions to scientists wanting to couple, extend - or simply run - existing models. For scientists whose main focus may not be computer science these barriers become even larger and become significant logistical hurdles. And this is all before the scientific difficulties of coupling or running models are addressed. The CSDMS Python Modeling Toolkit (PyMT) was developed to help non-computer scientists deal with these sorts of modeling logistics. PyMT is the fundamental package the Community Surface Dynamics Modeling System uses for the coupling of models that expose the Basic Modeling Interface (BMI). It contains: Tools necessary for coupling models of disparate time and space scales (including grid mappers) Time-steppers that coordinate the sequencing of coupled models Exchange of data between BMI-enabled models Wrappers that automatically load BMI-enabled models into the PyMT framework Utilities that support open-source interfaces (UGRID, SGRID,CSDMS Standard Names, etc.) A collection of community-submitted models, written in a variety of programminglanguages, from a variety of process domains - but all usable from within the Python programming language A plug-in framework for adding additional BMI-enabled models to the framework In this presentation we intoduce the basics of the PyMT as well as provide an example of coupling

  9. SMOG 2: A Versatile Software Package for Generating Structure-Based Models.

    Science.gov (United States)

    Noel, Jeffrey K; Levi, Mariana; Raghunathan, Mohit; Lammert, Heiko; Hayes, Ryan L; Onuchic, José N; Whitford, Paul C

    2016-03-01

    Molecular dynamics simulations with coarse-grained or simplified Hamiltonians have proven to be an effective means of capturing the functionally important long-time and large-length scale motions of proteins and RNAs. Originally developed in the context of protein folding, structure-based models (SBMs) have since been extended to probe a diverse range of biomolecular processes, spanning from protein and RNA folding to functional transitions in molecular machines. The hallmark feature of a structure-based model is that part, or all, of the potential energy function is defined by a known structure. Within this general class of models, there exist many possible variations in resolution and energetic composition. SMOG 2 is a downloadable software package that reads user-designated structural information and user-defined energy definitions, in order to produce the files necessary to use SBMs with high performance molecular dynamics packages: GROMACS and NAMD. SMOG 2 is bundled with XML-formatted template files that define commonly used SBMs, and it can process template files that are altered according to the needs of each user. This computational infrastructure also allows for experimental or bioinformatics-derived restraints or novel structural features to be included, e.g. novel ligands, prosthetic groups and post-translational/transcriptional modifications. The code and user guide can be downloaded at http://smog-server.org/smog2.

  10. SMOG 2: A Versatile Software Package for Generating Structure-Based Models.

    Directory of Open Access Journals (Sweden)

    Jeffrey K Noel

    2016-03-01

    Full Text Available Molecular dynamics simulations with coarse-grained or simplified Hamiltonians have proven to be an effective means of capturing the functionally important long-time and large-length scale motions of proteins and RNAs. Originally developed in the context of protein folding, structure-based models (SBMs have since been extended to probe a diverse range of biomolecular processes, spanning from protein and RNA folding to functional transitions in molecular machines. The hallmark feature of a structure-based model is that part, or all, of the potential energy function is defined by a known structure. Within this general class of models, there exist many possible variations in resolution and energetic composition. SMOG 2 is a downloadable software package that reads user-designated structural information and user-defined energy definitions, in order to produce the files necessary to use SBMs with high performance molecular dynamics packages: GROMACS and NAMD. SMOG 2 is bundled with XML-formatted template files that define commonly used SBMs, and it can process template files that are altered according to the needs of each user. This computational infrastructure also allows for experimental or bioinformatics-derived restraints or novel structural features to be included, e.g. novel ligands, prosthetic groups and post-translational/transcriptional modifications. The code and user guide can be downloaded at http://smog-server.org/smog2.

  11. Modeling viscoelastic deformation of the earth due to surface loading by commercial finite element package - ABAQUS

    Science.gov (United States)

    Kit Wong, Ching; Wu, Patrick

    2017-04-01

    Wu (2004) developed a transformation scheme to model viscoelatic deformation due to glacial loading by commercial finite element package - ABAQUS. Benchmark tests confirmed that this method works extremely well on incompressible earth model. Bangtsson & Lund (2008),however, showed that the transformation scheme would lead to incorrect results if compressible material parameters are used. Their study implies that Wu's method of stress transformation is inadequate to model the load induced deformation of a compressible earth under the framework of ABAQUS. In light of this, numerical experiments are carried out to find if there exist other methods that serve this purpose. All the tested methods are not satisfying as the results failed to converge through iterations, except at the elastic limit. Those tested methods will be outlined and the results will be presented. Possible reasons of failure will also be discussed. Bängtsson, E., & Lund, B. (2008). A comparison between two solution techniques to solve the equations of glacially induced deformation of an elastic Earth. International journal for numerical methods in engineering, 75(4), 479-502. Wu, P. (2004). Using commercial finite element packages for the study of earth deformations, sea levels and the state of stress. Geophysical Journal International, 158(2), 401-408.

  12. Implementation of the GFS physical package in the GRAPES regional model: single column experiment

    Science.gov (United States)

    Chen, Baode; Huang, Wei; Bao, Jian-wen

    2015-04-01

    There is a growing concern about coupling among physical components in NWP models. The Physics package of the NCEP Global Forecast System (GFS) has been considerably turned and connection among various components is well considered. Thus, the full GFS physical package was implemented into the GRAPES-MESO and its single column version as well. Using the data collected at ARM Southern Great Plain site during the summer 1997 Intensive Observing Period, several experiments of single-column model (SCM) were conducted to test performance of a set of original physical processes of GRAPES(CTL experiment) and the GFS physics package implemented(GFS experiment). Temperature, moisture, radiation, surface heat flux, surface air temperature and precipitation are evaluated. It is found that potential temperature and vapor mixing ratio simulated by GFS experiment is more accurate than that of CTL experiment. Errors of surface downward solar and long-wave radiation simulated by GFS experiment are less than that of CTL experiment and upward latent and sensible heat flux are also better agreeing with observation. The maximum and minimum 2-m air temperatures of the GFS experiment are close to observation compared with that of CTL experiment. Analysis of precipitation simulated shows that both sets of physical processes well reproduce heavy rainfall events. Failure and delay of moderate rainfall events and over predictions of drizzle events are commonly found for two sets of experiments. For the case of three rainfall events, the errors of potential temperature and vapor mixing ratio simulated by GFS experiment were smaller than that of CTL experiment. It is shown that the late occurrences of rainfall are resulted from a more stable temperature profile and lower moisture simulated in boundary layer than those from the observation prior to rainfall. When the simulated rainfall occurs, the simulated temperature and moisture become more favorable to the precipitation than observation.

  13. Packaging fluency

    DEFF Research Database (Denmark)

    Mocanu, Ana; Chrysochou, Polymeros; Bogomolova, Svetlana

    2011-01-01

    Research on packaging stresses the need for packaging design to read easily, presuming fast and accurate processing of product-related information. In this paper we define this property of packaging as “packaging fluency”. Based on the existing marketing and cognitive psychology literature...... on packaging design and processing fluency, our aim is to define and conceptualise packaging fluency. We stress the important role of packaging fluency since it is anticipated that a fluent package would influence the evaluative judgments for a product. We conclude this paper by setting the research agenda...

  14. The production-distribution problem with order acceptance and package delivery: models and algorithm

    Directory of Open Access Journals (Sweden)

    Khalili Majid

    2016-01-01

    Full Text Available The production planning and distribution are among the most important decisions in the supply chain. Classically, in this problem, it is assumed that all orders have to produced and separately delivered; while, in practice, an order may be rejected if the cost that it brings to the supply chain exceeds its revenue. Moreover, orders can be delivered in a batch to reduce the related costs. This paper considers the production planning and distribution problem with order acceptance and package delivery to maximize the profit. At first, a new mathematical model based on mixed integer linear programming is developed. Using commercial optimization software, the model can optimally solve small or even medium sized instances. For large instances, a solution method, based on imperialist competitive algorithms, is also proposed. Using numerical experiments, the proposed model and algorithm are evaluated.

  15. Application of Thermal Network Model to Transient Thermal Analysis of Power Electronic Package Substrate

    Directory of Open Access Journals (Sweden)

    Masaru Ishizuka

    2011-01-01

    Full Text Available In recent years, there is a growing demand to have smaller and lighter electronic circuits which have greater complexity, multifunctionality, and reliability. High-density multichip packaging technology has been used in order to meet these requirements. The higher the density scale is, the larger the power dissipation per unit area becomes. Therefore, in the designing process, it has become very important to carry out the thermal analysis. However, the heat transport model in multichip modules is very complex, and its treatment is tedious and time consuming. This paper describes an application of the thermal network method to the transient thermal analysis of multichip modules and proposes a simple model for the thermal analysis of multichip modules as a preliminary thermal design tool. On the basis of the result of transient thermal analysis, the validity of the thermal network method and the simple thermal analysis model is confirmed.

  16. CFD modeling to improve safe and efficient distribution of chlorine dioxide gas for packaging fresh produce

    Science.gov (United States)

    The efficiency of the packaging system in inactivating food borne pathogens and prolonging the shelf life of fresh-cut produce is influenced by the design of the package apart from material and atmospheric conditions. Three different designs were considered to determine a specific package design ens...

  17. Inference in Graphical Gaussian Models with Edge and Vertex Symmetries with the gRc Package for R

    DEFF Research Database (Denmark)

    Højsgaard, Søren; Lauritzen, Steffen L

    2007-01-01

    In this paper we present the R package gRc for statistical inference in graphical Gaussian models in which symmetry restrictions have been imposed on the concentration or partial correlation matrix. The models are represented by coloured graphs where parameters associated with edges or vertices o...... of same colour are restricted to being identical. We describe algorithms for maximum likelihood estimation and discuss model selection issues. The paper illustrates the practical use of the gRc package......In this paper we present the R package gRc for statistical inference in graphical Gaussian models in which symmetry restrictions have been imposed on the concentration or partial correlation matrix. The models are represented by coloured graphs where parameters associated with edges or vertices...

  18. Nonlinearities and transit times in soil organic matter models: new developments in the SoilR package

    Science.gov (United States)

    Sierra, Carlos; Müller, Markus

    2016-04-01

    SoilR is an R package for implementing diverse models representing soil organic matter dynamics. In previous releases of this package, we presented the implementation of linear first-order models with any number of pools as well as radiocarbon dynamics. We present here new improvements of the package regarding the possibility to implement models with nonlinear interactions among state variables and the possibility to calculate ages and transit times for nonlinear models with time dependencies. We show here examples on how to implement model structures with Michaelis-Menten terms for explicit microbial growth and resource use efficiency, and Langmuir isotherms for representing adsorption of organic matter to mineral surfaces. These nonlinear terms can be implemented for any number of organic matter pools, microbial functional groups, or mineralogy, depending on user's requirements. Through a simple example, we also show how transit times of organic matter in soils are controlled by the time-dependencies of the input terms.

  19. A suite of R packages for web-enabled modeling and analysis of surface waters

    Science.gov (United States)

    Read, J. S.; Winslow, L. A.; Nüst, D.; De Cicco, L.; Walker, J. I.

    2014-12-01

    Researchers often create redundant methods for downloading, manipulating, and analyzing data from online resources. Moreover, the reproducibility of science can be hampered by complicated and voluminous data, lack of time for documentation and long-term maintenance of software, and fear of exposing programming skills. The combination of these factors can encourage unshared one-off programmatic solutions instead of openly provided reusable methods. Federal and academic researchers in the water resources and informatics domains have collaborated to address these issues. The result of this collaboration is a suite of modular R packages that can be used independently or as elements in reproducible analytical workflows. These documented and freely available R packages were designed to fill basic needs for the effective use of water data: the retrieval of time-series and spatial data from web resources (dataRetrieval, geoknife), performing quality assurance and quality control checks of these data with robust statistical methods (sensorQC), the creation of useful data derivatives (including physically- and biologically-relevant indices; GDopp, LakeMetabolizer), and the execution and evaluation of models (glmtools, rLakeAnalyzer). Here, we share details and recommendations for the collaborative coding process, and highlight the benefits of an open-source tool development pattern with a popular programming language in the water resources discipline (such as R). We provide examples of reproducible science driven by large volumes of web-available data using these tools, explore benefits of accessing packages as standardized web processing services (WPS) and present a working platform that allows domain experts to publish scientific algorithms in a service-oriented architecture (WPS4R). We assert that in the era of open data, tools that leverage these data should also be freely shared, transparent, and developed in an open innovation environment.

  20. Clinical laboratory as an economic model for business performance analysis.

    Science.gov (United States)

    Buljanović, Vikica; Patajac, Hrvoje; Petrovecki, Mladen

    2011-08-15

    To perform SWOT (strengths, weaknesses, opportunities, and threats) analysis of a clinical laboratory as an economic model that may be used to improve business performance of laboratories by removing weaknesses, minimizing threats, and using external opportunities and internal strengths. Impact of possible threats to and weaknesses of the Clinical Laboratory at Našice General County Hospital business performance and use of strengths and opportunities to improve operating profit were simulated using models created on the basis of SWOT analysis results. The operating profit as a measure of profitability of the clinical laboratory was defined as total revenue minus total expenses and presented using a profit and loss account. Changes in the input parameters in the profit and loss account for 2008 were determined using opportunities and potential threats, and economic sensitivity analysis was made by using changes in the key parameters. The profit and loss account and economic sensitivity analysis were tools for quantifying the impact of changes in the revenues and expenses on the business operations of clinical laboratory. Results of simulation models showed that operational profit of €470 723 in 2008 could be reduced to only €21 542 if all possible threats became a reality and current weaknesses remained the same. Also, operational gain could be increased to €535 804 if laboratory strengths and opportunities were utilized. If both the opportunities and threats became a reality, the operational profit would decrease by €384 465. The operational profit of the clinical laboratory could be significantly reduced if all threats became a reality and the current weaknesses remained the same. The operational profit could be increased by utilizing strengths and opportunities as much as possible. This type of modeling may be used to monitor business operations of any clinical laboratory and improve its financial situation by implementing changes in the next fiscal

  1. Clinical laboratory as an economic model for business performance analysis

    Science.gov (United States)

    Buljanović, Vikica; Patajac, Hrvoje; Petrovečki, Mladen

    2011-01-01

    Aim To perform SWOT (strengths, weaknesses, opportunities, and threats) analysis of a clinical laboratory as an economic model that may be used to improve business performance of laboratories by removing weaknesses, minimizing threats, and using external opportunities and internal strengths. Methods Impact of possible threats to and weaknesses of the Clinical Laboratory at Našice General County Hospital business performance and use of strengths and opportunities to improve operating profit were simulated using models created on the basis of SWOT analysis results. The operating profit as a measure of profitability of the clinical laboratory was defined as total revenue minus total expenses and presented using a profit and loss account. Changes in the input parameters in the profit and loss account for 2008 were determined using opportunities and potential threats, and economic sensitivity analysis was made by using changes in the key parameters. The profit and loss account and economic sensitivity analysis were tools for quantifying the impact of changes in the revenues and expenses on the business operations of clinical laboratory. Results Results of simulation models showed that operational profit of €470 723 in 2008 could be reduced to only €21 542 if all possible threats became a reality and current weaknesses remained the same. Also, operational gain could be increased to €535 804 if laboratory strengths and opportunities were utilized. If both the opportunities and threats became a reality, the operational profit would decrease by €384 465. Conclusion The operational profit of the clinical laboratory could be significantly reduced if all threats became a reality and the current weaknesses remained the same. The operational profit could be increased by utilizing strengths and opportunities as much as possible. This type of modeling may be used to monitor business operations of any clinical laboratory and improve its financial situation by

  2. Analytic implementation of the GRAAL model: Application to a R7T7-type glass package in a geological disposal environment

    Energy Technology Data Exchange (ETDEWEB)

    Minet, Y., E-mail: yves.minet@cea.f [CEA Marcoule, DTCD/SECM/LCLT, BP 17171, 30207 Bagnols-sur-Ceze Cedex (France); Bonin, B. [CEA Saclay, DEN/DIR/DS, 91191 Gif-sur-Yvette Cedex (France); Gin, S.; Frugier, P. [CEA Marcoule, DTCD/SECM/LCLT, BP 17171, 30207 Bagnols-sur-Ceze Cedex (France)

    2010-09-30

    The Glass Reactivity with Allowance for the Alteration Layer Model (GRAAL) was proposed in 2008 to describe borosilicate nuclear glass alteration based on coupling an affinity law with the formation and dissolution of a passivating reactive interface. It is examined here in a simplified form in which only the affinity with respect to silicon is taken into account with a concentration at saturation C{sub sat}, and the precipitation of neoformed phases is described by an affine relation for silicon above a precipitation threshold C{sub sat}{sup '}. This simplified 'analytical GRAAL' model is capable of predicting the quantities of altered glass and the silicon and boron concentration variations in analytical or semi-analytical form, and thereby identify the main characteristic quantities of the system. The model was tested against a series of laboratory experiments lasting from a few days to a few years; its sensitivity to the parameter values was examined, and the model was validated with respect to SON68 glass alteration in initially pure water. It was then applied to the alteration of a glass package in a repository over periods of up to a million years, by means of exploratory calculations comprising a sensitivity study of the internal model parameters and extrapolation to the temperatures expected in a geological repository in order to identify the parameters and mechanisms having the greatest impact on the residual alteration rate. Alteration is controlled by the precipitation of neoformed phases in every case. The transient conditions are of very limited duration with respect to either silicon or boron (no more than a 100 years, with less than 0.01% alteration of the package). In the precipitation law used in the model, the residual alteration rate and total package lifetime are determined primarily by two parameters: k' (the precipitation kinetics) and {sigma}' (the precipitate surface area per unit volume in the geological barrier

  3. demogR: A Package for the Construction and Analysis of Age-structured Demographic Models in R

    Directory of Open Access Journals (Sweden)

    James Holland Jones

    2007-08-01

    Full Text Available The analysis of matrix population models has become a fundamental tool in ecology, conservation biology, and life history theory. In this paper, I present demogR, a package for analyzing age-structured population models in R. The package includes tools for the construction and analysis of matrix population models. In addition to the standard analyses commonly used in evolutionary demography and conservation biology, demogR contains a variety of tools from classical demography. This includes the construction of period life tables, and the generation of model mortality and fertility schedules for human populations. The tools in demogR are generally applicable to age-structured populations but are particularly useful for analyzing problems in human ecology. I illustrate some of the capabilities of the package by doing an evolutionary demographic analysis of several human populations.

  4. Packaging fluency

    DEFF Research Database (Denmark)

    Mocanu, Ana; Chrysochou, Polymeros; Bogomolova, Svetlana

    2011-01-01

    Research on packaging stresses the need for packaging design to read easily, presuming fast and accurate processing of product-related information. In this paper we define this property of packaging as “packaging fluency”. Based on the existing marketing and cognitive psychology literature on pac...

  5. PROCESS MODELLING OF ROCK SAMPLE HANDLING IN PETROPHYSICAL LABORATORY

    Directory of Open Access Journals (Sweden)

    Adaleta Perković

    2010-12-01

    Full Text Available Everyday procedures carried out in petrophysical laboratory can be defined as a complete cycle of business processes. Sample handling process is one of the most significant and demanding procedures. It starts with sample receiving in laboratory and then subsequently, series of analyses and measurements are carrying out resulting in petrophysical parameters. Sample handling process ends with sample storage and archiving of obtained measurement data. Process model is used for description of repeating activities. Sample handling process is presented by graphical method and use of eEPC diagram (extended Event-Driven Process Chain which describe process based on events. Created process model jointly binds static laboratory resources (measuring instruments, computers and data, speeds up process with increasing the user’s efficiency and with improvements of data and information exchange. Besides flow of activity, model of data sample handling includes information about system components (laboratory equipment and software applications that carry out activities. Described model, with minor modifications and adaptations, can be used in any laboratory that is dealing with samples (the paper is published in Croatian.

  6. The last developments of the airGR R-package, an open source software for rainfall-runoff modelling

    Science.gov (United States)

    Thirel, Guillaume; Delaigue, Olivier; Coron, Laurent; Perrin, Charles; Andréassian, Vazken

    2017-04-01

    Lumped hydrological models are useful and convenient tools for research, engineering and educational purposes. They propose catchment-scale representations of the precipitation-discharge relationship. Thanks to their limited data requirements, they can be easily implemented and run. With such models, it is possible to simulate a number of hydrological key processes over the catchment with limited structural and parametric complexity, typically evapotranspiration, runoff, underground losses, etc. The Hydrology Group at Irstea (Antony) has been developing a suite of rainfall-runoff models over the past 30 years with the main objectives of designing models as efficient as possible in terms of streamflow simulation, applicable to a wide range of catchments and having low data requirements. This resulted in a suite of models running at different time steps (from hourly to annual) applicable for various issues including water balance estimation, forecasting, simulation of impacts and scenario testing. Recently, Irstea has developed an easy-to-use R-package (R Core Team, 2016), called airGR (Coron et al., 2016, 2017), to make these models widely available. It includes: - the water balance annual GR1A model, - the monthly GR2M model, - three versions of the daily model, namely GR4J, GR5J and GR6J, - the hourly GR4H model, - a degree-day snow model CemaNeige. The airGR package has been designed to facilitate the use by non-expert users and allow the addition of evaluation criteria, models or calibration algorithm selected by the end-user. Each model core is coded in FORTRAN to ensure low computational time. The other package functions (i.e. mainly the calibration algorithm and the efficiency criteria) are coded in R. The package is also used for educational purposes. It allows for convenient implementation of model inter-comparisons and large sample hydrology experiments. The airGR package undergoes continuous developments for improving the efficiency, computational time

  7. Realistic modeling of clinical laboratory operation by computer simulation.

    Science.gov (United States)

    Vogt, W; Braun, S L; Hanssmann, F; Liebl, F; Berchtold, G; Blaschke, H; Eckert, M; Hoffmann, G E; Klose, S

    1994-06-01

    An important objective of laboratory management is to adjust the laboratory's capability to the needs of patients' care as well as economy. The consequences of management may be changes in laboratory organization, equipment, or personnel planning. At present only one's individual experience can be used for making such decisions. We have investigated whether the techniques of operations research could be transferred to a clinical laboratory and whether an adequate simulation model of the laboratory could be realized. First we listed and documented the system design and the process flow for each single laboratory request. These input data were linked by the simulation model (programming language SIMSCRIPT II.5). The output data (turnaround times, utilization rates, and analysis of queue length) were validated by comparison with the current performance data obtained by tracking specimen flow. Congruence of the data was excellent (within +/- 4%). In planning experiments we could study the consequences of changes in order entry, staffing, and equipment on turnaround times, utilization, and queue lengths. We conclude that simulation can be a valuable tool for better management decisions.

  8. Dental Biofilm and Laboratory Microbial Culture Models for Cariology Research

    Directory of Open Access Journals (Sweden)

    Ollie Yiru Yu

    2017-06-01

    Full Text Available Dental caries form through a complex interaction over time among dental plaque, fermentable carbohydrate, and host factors (including teeth and saliva. As a key factor, dental plaque or biofilm substantially influence the characteristic of the carious lesions. Laboratory microbial culture models are often used because they provide a controllable and constant environment for cariology research. Moreover, they do not have ethical problems associated with clinical studies. The design of the microbial culture model varies from simple to sophisticated according to the purpose of the investigation. Each model is a compromise between the reality of the oral cavity and the simplification of the model. Researchers, however, can still obtain meaningful and useful results from the models they select. Laboratory microbial culture models can be categorized into a closed system and an open system. Models in the closed system have a finite supply of nutrients, and are also simple and cost-effective. Models in the open system enabled the supply of a fresh culture medium and the removal of metabolites and spent culture liquid simultaneously. They provide better regulation of the biofilm growth rate than the models in the closed system. This review paper gives an overview of the dental plaque biofilm and laboratory microbial culture models used for cariology research.

  9. Application of the Finite Elemental Analysis to Modeling Temperature Change of the Vaccine in an Insulated Packaging Container during Transport.

    Science.gov (United States)

    Ge, Changfeng; Cheng, Yujie; Shen, Yan

    2013-01-01

    This study demonstrated an attempt to predict temperatures of a perishable product such as vaccine inside an insulated packaging container during transport through finite element analysis (FEA) modeling. In order to use the standard FEA software for simulation, an equivalent heat conduction coefficient is proposed and calculated to describe the heat transfer of the air trapped inside the insulated packaging container. The three-dimensional, insulated packaging container is regarded as a combination of six panels, and the heat flow at each side panel is a one-dimension diffusion process. The transit-thermal analysis was applied to simulate the heat transition process from ambient environment to inside the container. Field measurements were carried out to collect the temperature during transport, and the collected data were compared to the FEA simulation results. Insulated packaging containers are used to transport temperature-sensitive products such as vaccine and other pharmaceutical products. The container is usually made of an extruded polystyrene foam filled with gel packs. World Health Organization guidelines recommend that all vaccines except oral polio vaccine be distributed in an environment where the temperature ranges between +2 to +8 °C. The primary areas of concern in designing the packaging for vaccine are how much of the foam thickness and gel packs should be used in order to keep the temperature in a desired range, and how to prevent the vaccine from exposure to freezing temperatures. This study uses numerical simulation to predict temperature change within an insulated packaging container in vaccine cold chain. It is our hope that this simulation will provide the vaccine industries with an alternative engineering tool to validate vaccine packaging and project thermal equilibrium within the insulated packaging container.

  10. Microelectronic packaging

    CERN Document Server

    Datta, M; Schultze, J Walter

    2004-01-01

    Microelectronic Packaging analyzes the massive impact of electrochemical technologies on various levels of microelectronic packaging. Traditionally, interconnections within a chip were considered outside the realm of packaging technologies, but this book emphasizes the importance of chip wiring as a key aspect of microelectronic packaging, and focuses on electrochemical processing as an enabler of advanced chip metallization.Divided into five parts, the book begins by outlining the basics of electrochemical processing, defining the microelectronic packaging hierarchy, and emphasizing the impac

  11. Model Testing - Bringing the Ocean into the Laboratory

    DEFF Research Database (Denmark)

    Aage, Christian

    2000-01-01

    Hydrodynamic model testing, the principle of bringing the ocean into the laboratory to study the behaviour of the ocean itself and the response of man-made structures in the ocean in reduced scale, has been known for centuries. Due to an insufficient understanding of the physics involved, however......, the early model tests often gave incomplete or directly misleading results.This keynote lecture deals with some of the possibilities and problems within the field of hydrodynamic and hydraulic model testing....

  12. TYPE A FISSILE PACKAGING FOR AIR TRANSPORT PROJECT OVERVIEW

    Energy Technology Data Exchange (ETDEWEB)

    Eberl, K.; Blanton, P.

    2013-10-11

    This paper presents the project status of the Model 9980, a new Type A fissile packaging for use in air transport. The Savannah River National Laboratory (SRNL) developed this new packaging to be a light weight (<150-lb), drum-style package and prepared a Safety Analysis for Packaging (SARP) for submission to the DOE/EM. The package design incorporates unique features and engineered materials specifically designed to minimize packaging weight and to be in compliance with 10CFR71 requirements. Prototypes were fabricated and tested to evaluate the design when subjected to Normal Conditions of Transport (NCT) and Hypothetical Accident Conditions (HAC). An overview of the design details, results of the regulatory testing, and lessons learned from the prototype fabrication for the 9980 will be presented.

  13. MuLV packaging systems as models for estimating/measuring retrovirus recombination frequency.

    Science.gov (United States)

    Patience, C; Takeuch, Y; Cosset, F L; Weiss, R A

    2001-01-01

    Interaction of retrovirus vectors and endogenous retroviruses present in packaging cell lines and target cells may result in the formation of recombinant viruses. Using sensitive RT-PCR assays, we have investigated human and murine gene therapy packaging cell lines for the incorporation of endogenous retrovirus transcripts into murine leukaemia virus (MLV) vector particles and whether vector genomes are incorporated into human endogenous retrovirus (HERV) particles. VL30 endogenous retrovirus sequences were packaged in particles produced by the murine AM12 packaging system. For every seven MLV-derived -galactosidase beta-Gal vector genomes present in the particles, one copy of VL30 was also packaged. Although human FLY packaging cells expressed HERV transcripts (HERV-K, HuRT, type C, and RTVL-H), none was detectable in the MLV vector particles released from the cells. Non-specific packaging of the MLV gag-pol expression vector transcripts was detected in the FLY virions at a low level (one in 17,000 sequences). In other experiments, gag proteins produced by HERV-K particles present in human teratocarcinoma cells did not appear to package MLV-based vectors that expressed Gal transcripts. These findings indicate that retrovirus vectors interact with human packaging cells to produce retrovirus particles that are far less contaminated by endogenous viral sequences or other types of extraneous particles than murine packaging cells.

  14. ARM Cloud Radar Simulator Package for Global Climate Models Value-Added Product

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Yuying [North Carolina State Univ., Raleigh, NC (United States); Xie, Shaocheng [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-05-01

    It has been challenging to directly compare U.S. Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) Climate Research Facility ground-based cloud radar measurements with climate model output because of limitations or features of the observing processes and the spatial gap between model and the single-point measurements. To facilitate the use of ARM radar data in numerical models, an ARM cloud radar simulator was developed to converts model data into pseudo-ARM cloud radar observations that mimic the instrument view of a narrow atmospheric column (as compared to a large global climate model [GCM] grid-cell), thus allowing meaningful comparison between model output and ARM cloud observations. The ARM cloud radar simulator value-added product (VAP) was developed based on the CloudSat simulator contained in the community satellite simulator package, the Cloud Feedback Model Intercomparison Project (CFMIP) Observation Simulator Package (COSP) (Bodas-Salcedo et al., 2011), which has been widely used in climate model evaluation with satellite data (Klein et al., 2013, Zhang et al., 2010). The essential part of the CloudSat simulator is the QuickBeam radar simulator that is used to produce CloudSat-like radar reflectivity, but is capable of simulating reflectivity for other radars (Marchand et al., 2009; Haynes et al., 2007). Adapting QuickBeam to the ARM cloud radar simulator within COSP required two primary changes: one was to set the frequency to 35 GHz for the ARM Ka-band cloud radar, as opposed to 94 GHz used for the CloudSat W-band radar, and the second was to invert the view from the ground to space so as to attenuate the beam correctly. In addition, the ARM cloud radar simulator uses a finer vertical resolution (100 m compared to 500 m for CloudSat) to resolve the more detailed structure of clouds captured by the ARM radars. The ARM simulator has been developed following the COSP workflow (Figure 1) and using the capabilities available in COSP

  15. Laboratory simulation and modeling of size, shape distributed interstellar graphite dust analogues: A comparative study

    Science.gov (United States)

    Boruah, Manash J.; Gogoi, Ankur; Ahmed, Gazi A.

    2016-06-01

    The computation of the light scattering properties of size and shape distributed interstellar graphite dust analogues using discrete dipole approximation (DDA) is presented. The light scattering properties of dust particles of arbitrary shapes having sizes ranging from 0.5 to 5.0 μm were computed using DDSCAT 7.3.0 software package and an indigenously developed post-processing tool for size and shape averaging. In order to model realistic samples of graphite dust and compute their light scattering properties using DDA, different target geometries were generated to represent the graphite particle composition in terms of surface smoothness, surface roughness and aggregation or their combination, for using as the target for DDSCAT calculations. A comparison of the theoretical volume scattering function at 543.5 nm and 632.8 nm incident wavelengths with laboratory simulation is also presented in this paper.

  16. A flexible open-source toolbox for robust end-member modelling analysis - The R-package EMMAgeo

    Science.gov (United States)

    Dietze, Michael; Dietze, Elisabeth

    2013-04-01

    Interpreting geomorphological and sedimentological processes from grain-size data in environmental archives typically runs into problems when source- and process-related grain-size distributions become mixed during deposition. A powerful approach to overcome this ambiguity is to statistically "unmix" the samples. Typical algorithms use eigenspace decomposition and techniques of dimension reduction. This contribution presents a package for the free statistical software R. Some of the great advantages of R and R-packages are the open code structure, flexibility and low programming effort. The package contains a series of flexible, ready-to-use functions to perform different tasks of data tests, preparation, modelling and visualisation. The package originated from a recently presented Matlab-based end-member modelling algorithm (Dietze et al., 2012, SedGeol). It supports simple modelling of grain-size end-member loadings and scores (eigenspace extraction, factor rotation, data scaling, non-negative least squares solving) along with several measures of model quality. The package further provides preprocessing tools (e.g. grain-size scale conversions, tests of data structure, weight factor limit inference, determination of minimum, optimum and maximum number of meaningful end-members) and allows to model data sets with artificial or user-defined end-member loadings. EMMAgeo also supports inferring uncertainty estimation from a series of plausible model runs and the determination of robust end-members. The contribution presents important package functions, thereby illustrating how large data sets of artificial and natural grain-size samples from different depositional environments can be analysed to infer quantified process-related proxies.

  17. airGR: a suite of lumped hydrological models in an R-package

    Science.gov (United States)

    Coron, Laurent; Perrin, Charles; Delaigue, Olivier; Andréassian, Vazken; Thirel, Guillaume

    2016-04-01

    Lumped hydrological models are useful and convenient tools for research, engineering and educational purposes. They propose catchment-scale representations of the precipitation-discharge relationship. Thanks to their limited data requirements, they can be easily implemented and run. With such models, it is possible to simulate a number of hydrological key processes over the catchment with limited structural and parametric complexity, typically evapotranspiration, runoff, underground losses, etc. The Hydrology Group at Irstea (Antony) has been developing a suite of rainfall-runoff models over the past 30 years with the main objectives of designing models as efficient as possible in terms of streamflow simulation, applicable to a wide range of catchments and having low data requirements. This resulted in a suite of models running at different time steps (from hourly to annual) applicable for various issues including water balance estimation, forecasting, simulation of impacts and scenario testing. Recently, Irstea has developed an easy-to-use R-package (R Core Team, 2015), called airGR, to make these models widely available. It includes: - the water balance annual GR1A (Mouehli et al., 2006), - the monthly GR2M (Mouehli, 2003) models, - three versions of the daily model, namely GR4J (Perrin et al., 2003), GR5J (Le Moine, 2008) and GR6J (Pushpalatha et al., 2011), - the hourly GR4H model (Mathevet, 2005), - a degree-day snow module CemaNeige (Valéry et al., 2014). The airGR package has been designed to facilitate the use by non-expert users and allow the addition of evaluation criteria, models or calibration algorithms selected by the end-user. Each model core is coded in FORTRAN to ensure low computational time. The other package functions (i.e. mainly the calibration algorithm and the efficiency criteria) are coded in R. The package is already used for educational purposes. The presentation will detail the main functionalities of the package and present a case

  18. Geochemistry Model Abstraction and Sensitivity Studies for the 21 PWR CSNF Waste Package

    Energy Technology Data Exchange (ETDEWEB)

    P. Bernot; S. LeStrange; E. Thomas; K. Zarrabi; S. Arthur

    2002-10-29

    The CSNF geochemistry model abstraction, as directed by the TWP (BSC 2002b), was developed to provide regression analysis of EQ6 cases to obtain abstracted values of pH (and in some cases HCO{sub 3}{sup -} concentration) for use in the Configuration Generator Model. The pH of the system is the controlling factor over U mineralization, CSNF degradation rate, and HCO{sub 3}{sup -} concentration in solution. The abstraction encompasses a large variety of combinations for the degradation rates of materials. The ''base case'' used EQ6 simulations looking at differing steel/alloy corrosion rates, drip rates, and percent fuel exposure. Other values such as the pH/HCO{sub 3}{sup -} dependent fuel corrosion rate and the corrosion rate of A516 were kept constant. Relationships were developed for pH as a function of these differing rates to be used in the calculation of total C and subsequently, the fuel rate. An additional refinement to the abstraction was the addition of abstracted pH values for cases where there was limited O{sub 2} for waste package corrosion and a flushing fluid other than J-13, which has been used in all EQ6 calculation up to this point. These abstractions also used EQ6 simulations with varying combinations of corrosion rates of materials to abstract the pH (and HCO{sub 3}{sup -} in the case of the limiting O{sub 2} cases) as a function of WP materials corrosion rates. The goodness of fit for most of the abstracted values was above an R{sup 2} of 0.9. Those below this value occurred during the time at the very beginning of WP corrosion when large variations in the system pH are observed. However, the significance of F-statistic for all the abstractions showed that the variable relationships are significant. For the abstraction, an analysis of the minerals that may form the ''sludge'' in the waste package was also presented. This analysis indicates that a number a different iron and aluminum minerals may form in

  19. A bunswik lens model of consumer health judgments of packaged foods

    DEFF Research Database (Denmark)

    Orquin, Jacob Lund

    2014-01-01

    representativeness. The study revealed that the objective healthfulness criterion is highly predictable on the basis of cues such as the food category, brand, carbohydrate content, and whether the food is a typical “light” product. However, consumer judgments of food healthfulness are based almost entirely...... criterion was calculated for each product according to its specific nutrition values using a validated nutrition profile. The lens model included explicit cues such as nutrition values, nutrition and health claims, food category, and brand and implicit cues such a packaging design and category...... on the food category and to a lesser extent on the brand and consumer familiarity with the product. The results are in conflict with consumers’ self-reported use of nutrition information but are in accordance with findings from studies using implicit methods....

  20. Optimal Non-Invasive Fault Classification Model for Packaged Ceramic Tile Quality Monitoring Using MMW Imaging

    Science.gov (United States)

    Agarwal, Smriti; Singh, Dharmendra

    2016-04-01

    Millimeter wave (MMW) frequency has emerged as an efficient tool for different stand-off imaging applications. In this paper, we have dealt with a novel MMW imaging application, i.e., non-invasive packaged goods quality estimation for industrial quality monitoring applications. An active MMW imaging radar operating at 60 GHz has been ingeniously designed for concealed fault estimation. Ceramic tiles covered with commonly used packaging cardboard were used as concealed targets for undercover fault classification. A comparison of computer vision-based state-of-the-art feature extraction techniques, viz, discrete Fourier transform (DFT), wavelet transform (WT), principal component analysis (PCA), gray level co-occurrence texture (GLCM), and histogram of oriented gradient (HOG) has been done with respect to their efficient and differentiable feature vector generation capability for undercover target fault classification. An extensive number of experiments were performed with different ceramic tile fault configurations, viz., vertical crack, horizontal crack, random crack, diagonal crack along with the non-faulty tiles. Further, an independent algorithm validation was done demonstrating classification accuracy: 80, 86.67, 73.33, and 93.33 % for DFT, WT, PCA, GLCM, and HOG feature-based artificial neural network (ANN) classifier models, respectively. Classification results show good capability for HOG feature extraction technique towards non-destructive quality inspection with appreciably low false alarm as compared to other techniques. Thereby, a robust and optimal image feature-based neural network classification model has been proposed for non-invasive, automatic fault monitoring for a financially and commercially competent industrial growth.

  1. CARBayes: An R Package for Bayesian Spatial Modeling with Conditional Autoregressive Priors

    Directory of Open Access Journals (Sweden)

    Duncan Lee

    2013-11-01

    Full Text Available Conditional autoregressive models are commonly used to represent spatial autocorrelation in data relating to a set of non-overlapping areal units, which arise in a wide variety of applications including agriculture, education, epidemiology and image analysis. Such models are typically specified in a hierarchical Bayesian framework, with inference based on Markov chain Monte Carlo (MCMC simulation. The most widely used software to fit such models is WinBUGS or OpenBUGS, but in this paper we introduce the R package CARBayes. The main advantage of CARBayes compared with the BUGS software is its ease of use, because: (1 the spatial adjacency information is easy to specify as a binary neighbourhood matrix; and (2 given the neighbourhood matrix the models can be implemented by a single function call in R. This paper outlines the general class of Bayesian hierarchical models that can be implemented in the CARBayes software, describes their implementation via MCMC simulation techniques, and illustrates their use with two worked examples in the fields of house price analysis and disease mapping.

  2. E-laboratories : agent-based modeling of electricity markets.

    Energy Technology Data Exchange (ETDEWEB)

    North, M.; Conzelmann, G.; Koritarov, V.; Macal, C.; Thimmapuram, P.; Veselka, T.

    2002-05-03

    Electricity markets are complex adaptive systems that operate under a wide range of rules that span a variety of time scales. These rules are imposed both from above by society and below by physics. Many electricity markets are undergoing or are about to undergo a transition from centrally regulated systems to decentralized markets. Furthermore, several electricity markets have recently undergone this transition with extremely unsatisfactory results, most notably in California. These high stakes transitions require the introduction of largely untested regulatory structures. Suitable laboratories that can be used to test regulatory structures before they are applied to real systems are needed. Agent-based models can provide such electronic laboratories or ''e-laboratories.'' To better understand the requirements of an electricity market e-laboratory, a live electricity market simulation was created. This experience helped to shape the development of the Electricity Market Complex Adaptive Systems (EMCAS) model. To explore EMCAS' potential as an e-laboratory, several variations of the live simulation were created. These variations probed the possible effects of changing power plant outages and price setting rules on electricity market prices.

  3. Reducing Fear of the Laboratory Rat: A Participant Modeling Approach.

    Science.gov (United States)

    Barber, Nigel

    1994-01-01

    Reports on the use of participant modeling in a study of 56 college-level students to reduce fear of laboratory rats. Discovers that even mild exposure reduced fear significantly. Finds that women were more fearful initially but that their fear reduction was equal to that of men. (CFR)

  4. A Mathematical Model of the Modified Atmosphere Packaging (MAP System for the Gas Transmission Rate of Fruit Produce

    Directory of Open Access Journals (Sweden)

    Li Li

    2010-01-01

    Full Text Available A mathematical model to predict oxygen, carbon dioxide, and water vapour exchanges in non-perforated and micro-perforated modified atmosphere packaging films has successfully been proposed. The transmission rate of gases was measured for films with thickness of 0.03 and 0.05 mm, perforation diameters of 0.5 and 2.0 mm, and temperatures of 0, 10 and 20 °C. Under most conditions, the increase in temperature and perforation diameter increased the transmission rate of oxygen, carbon dioxide, and water vapour, whereas the increase in film thickness decreased the transmission rate of the various gases. Validation of the proposed modified atmosphere packaging model was found to yield good prediction for gas concentrations and percentage losses in the mass of the produce after comparison with the experimental results of modified atmosphere packaging for tomato (Lycopersicon esculentum.

  5. Logistic random effects regression models: a comparison of statistical packages for binary and ordinal outcomes

    Directory of Open Access Journals (Sweden)

    Steyerberg Ewout W

    2011-05-01

    Full Text Available Abstract Background Logistic random effects models are a popular tool to analyze multilevel also called hierarchical data with a binary or ordinal outcome. Here, we aim to compare different statistical software implementations of these models. Methods We used individual patient data from 8509 patients in 231 centers with moderate and severe Traumatic Brain Injury (TBI enrolled in eight Randomized Controlled Trials (RCTs and three observational studies. We fitted logistic random effects regression models with the 5-point Glasgow Outcome Scale (GOS as outcome, both dichotomized as well as ordinal, with center and/or trial as random effects, and as covariates age, motor score, pupil reactivity or trial. We then compared the implementations of frequentist and Bayesian methods to estimate the fixed and random effects. Frequentist approaches included R (lme4, Stata (GLLAMM, SAS (GLIMMIX and NLMIXED, MLwiN ([R]IGLS and MIXOR, Bayesian approaches included WinBUGS, MLwiN (MCMC, R package MCMCglmm and SAS experimental procedure MCMC. Three data sets (the full data set and two sub-datasets were analysed using basically two logistic random effects models with either one random effect for the center or two random effects for center and trial. For the ordinal outcome in the full data set also a proportional odds model with a random center effect was fitted. Results The packages gave similar parameter estimates for both the fixed and random effects and for the binary (and ordinal models for the main study and when based on a relatively large number of level-1 (patient level data compared to the number of level-2 (hospital level data. However, when based on relatively sparse data set, i.e. when the numbers of level-1 and level-2 data units were about the same, the frequentist and Bayesian approaches showed somewhat different results. The software implementations differ considerably in flexibility, computation time, and usability. There are also differences in

  6. BPACK -- A computer model package for boiler reburning/co-firing performance evaluations. User`s manual, Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Wu, K.T.; Li, B.; Payne, R.

    1992-06-01

    This manual presents and describes a package of computer models uniquely developed for boiler thermal performance and emissions evaluations by the Energy and Environmental Research Corporation. The model package permits boiler heat transfer, fuels combustion, and pollutant emissions predictions related to a number of practical boiler operations such as fuel-switching, fuels co-firing, and reburning NO{sub x} reductions. The models are adaptable to most boiler/combustor designs and can handle burner fuels in solid, liquid, gaseous, and slurried forms. The models are also capable of performing predictions for combustion applications involving gaseous-fuel reburning, and co-firing of solid/gas, liquid/gas, gas/gas, slurry/gas fuels. The model package is conveniently named as BPACK (Boiler Package) and consists of six computer codes, of which three of them are main computational codes and the other three are input codes. The three main codes are: (a) a two-dimensional furnace heat-transfer and combustion code: (b) a detailed chemical-kinetics code; and (c) a boiler convective passage code. This user`s manual presents the computer model package in two volumes. Volume 1 describes in detail a number of topics which are of general users` interest, including the physical and chemical basis of the models, a complete description of the model applicability, options, input/output, and the default inputs. Volume 2 contains a detailed record of the worked examples to assist users in applying the models, and to illustrate the versatility of the codes.

  7. Information technologies and software packages for education of specialists in materials science [In Russian

    NARCIS (Netherlands)

    V. Krzhizhanovskaya; S. Ryaboshuk

    2009-01-01

    This paper presents methodological materials, interactive text-books and software packages developed and extensively used for education of specialists in materials science. These virtual laboratories for education and research are equipped with tutorials and software environment for modeling complex

  8. MODEL 9977 B(M)F-96 SAFETY ANALYSIS REPORT FOR PACKAGING

    Energy Technology Data Exchange (ETDEWEB)

    Abramczyk, G; Paul Blanton, P; Kurt Eberl, K

    2006-05-18

    This Safety Analysis Report for Packaging (SARP) documents the analysis and testing performed on and for the 9977 Shipping Package, referred to as the General Purpose Fissile Package (GPFP). The performance evaluation presented in this SARP documents the compliance of the 9977 package with the regulatory safety requirements for Type B packages. Per 10 CFR 71.59, for the 9977 packages evaluated in this SARP, the value of ''N'' is 50, and the Transport Index based on nuclear criticality control is 1.0. The 9977 package is designed with a high degree of single containment. The 9977 complies with 10 CFR 71 (2002), Department of Energy (DOE) Order 460.1B, DOE Order 460.2, and 10 CFR 20 (2003) for As Low As Reasonably Achievable (ALARA) principles. The 9977 also satisfies the requirements of the Regulations for the Safe Transport of Radioactive Material--1996 Edition (Revised)--Requirements. IAEA Safety Standards, Safety Series No. TS-R-1 (ST-1, Rev.), International Atomic Energy Agency, Vienna, Austria (2000). The 9977 package is designed, analyzed and fabricated in accordance with Section III of the American Society of Mechanical Engineers (ASME) Boiler and Pressure Vessel (B&PV) Code, 1992 edition.

  9. A Comparative Study of BDD Packages for Probabilistic Symbolic Model Checking

    NARCIS (Netherlands)

    van Dijk, Tom; Hahn, Ernst Moritz; Jansen, D.N.; Li, Yong; Neele, Thomas; Stoelinga, Mariëlle Ida Antoinette; Turrini, Andrea; Zhang, Lijun

    2015-01-01

    Symbolic data structures using Binary Decision Diagrams (BDDs) have been successfully used in the last decades to analyse large systems. While various BDD and MTBDD packages have been developed in the community, the CUDD package remains the default choice of most of the symbolic (probabilistic)

  10. Code package MAG c user tool for numerical modeling of 1D shock wave and dynamic processes in solids

    Science.gov (United States)

    Rudenko, Vladimir; Shaburov, Michail

    1999-06-01

    Design and theoretical and numerical preparation of shock wave experiments require, as a rule, conduction of a large amount of calculations. Usually preparation of a problem for numerical solution, calculation and processing of the results is done be programmers c mathematicians. The appearance of powerful personal computers and interface tools allows to develop such user-oriented programs that a researcher can handle them without the help of a mathematician, even if he does not have special programming background. Code package MAG for numerical solution of 1D system of equations of hydrodynamics, elastoplastics, heat conduction and magnetic hydrodynamic. A number of modern models of elastoplastics and kinetics of power materials is implemented in it. The package includes libraries of equations of state, thermal physical and electromagnetic properties of substances. The code package is an interactive visual medium providing a user with the following capabilities: ? Input and edit initial data for a problem; ? Calculate separate problems, as well as series of problems with a possibility of automatic variation of parameters; ? View the modeled phenomena dynamically using the means of visualization; ? Control the process of calculation: terminate the calculation, change parameters, make express-processing of the results, continue the calculation etc.; ? Process the numerical results producing final plots and tables; ? Record and store numerical results in databases, including the formats supported by Microsoft Word, Acces, Exel; ? Make dynamic visual comparison of the results of several simultaneous calculations; ? Carry out automatic numerical optimization of a selected experimental scheme. The package is easy in use, allows prompt input and convenient information processing. The validity of numerical results obtained with the package MAG has been proved by numerous hydrodynamic experiments and comparisons with numerical results from similar programs. The package was

  11. Software Package \\Nesvetay-3D" for modeling three-dimensional flows of monatomic rarefied gas

    Directory of Open Access Journals (Sweden)

    V. A. Titarev

    2014-01-01

    Full Text Available Analysis of three-dimensional rarefied gas flowsin microdevices (micropipes, micropumps etc and over re-entry vehicles requires development of methods of computational modelling. One of such methods is the direct numerical solution of the Boltzmann kinetic equation for the velocity distribution function with either exact or approximate (model collision integral. At present, for flows of monatomic rarefied gas the Shakhov model kinetic equation, also called S-model, has gained wide-spread use. The equation can be regarded as a model equation of the incomplete thirdorder approximation. Despite its relative simplicity, the S-model is still a complicated integrodifferential equation of high dimension. The numerical solution of such an equation requires high-accuracy parallel methods.The present work is a review of recent results concerning the development and application of three-dimensional computer package Nesvetay-3D intended for modelling of rarefied gas flows. The package solves Boltzmann kinetic equation with the BGK (Krook and Shakhov model collision integrals using the discrete velocity approach. Calculations are carried out in non-dimensional variables. A finite integration domain and a mesh are introduced in the molecular velocity space. Next, the kinetic equation is re-written as a system of kinetic equations for each of the discrete velocities. The system is solved using an implicit finite-volume method of Godunov type. The steady-state solution is computed by a time marching method. High order of spatial accuracy is achieved by using a piece-wise linear representation of the distribution function in each spatial cell. In general, the coefficients of such an approximation are found using the least-square method. Arbitrary unstructured meshes in the physical space can be used in calculations, which allow considering flows over objects of general geometrical shape. Conservative property of the method with respect to the model collision

  12. MCMC Methods for Multi-Response Generalized Linear Mixed Models: The MCMCglmm R Package

    Directory of Open Access Journals (Sweden)

    Jarrod Had

    2010-02-01

    Full Text Available Generalized linear mixed models provide a flexible framework for modeling a range of data, although with non-Gaussian response variables the likelihood cannot be obtained in closed form. Markov chain Monte Carlo methods solve this problem by sampling from a series of simpler conditional distributions that can be evaluated. The R package MCMCglmm implements such an algorithm for a range of model fitting problems. More than one response variable can be analyzed simultaneously, and these variables are allowed to follow Gaussian, Poisson, multi(binominal, exponential, zero-inflated and censored distributions. A range of variance structures are permitted for the random effects, including interactions with categorical or continuous variables (i.e., random regression, and more complicated variance structures that arise through shared ancestry, either through a pedigree or through a phylogeny. Missing values are permitted in the response variable(s and data can be known up to some level of measurement error as in meta-analysis. All simu- lation is done in C/ C++ using the CSparse library for sparse linear systems.

  13. Laboratory evaluation of a walleye (Sander vitreus) bioenergetics model

    Science.gov (United States)

    Madenjian, C.P.; Wang, C.; O'Brien, T. P.; Holuszko, M.J.; Ogilvie, L.M.; Stickel, R.G.

    2010-01-01

    Walleye (Sander vitreus) is an important game fish throughout much of North America. We evaluated the performance of the Wisconsin bioenergetics model for walleye in the laboratory. Walleyes were fed rainbow smelt (Osmerus mordax) in four laboratory tanks during a 126-day experiment. Based on a statistical comparison of bioenergetics model predictions of monthly consumption with the observed monthly consumption, we concluded that the bioenergetics model significantly underestimated food consumption by walleye in the laboratory. The degree of underestimation appeared to depend on the feeding rate. For the tank with the lowest feeding rate (1.4% of walleye body weight per day), the agreement between the bioenergetics model prediction of cumulative consumption over the entire 126-day experiment and the observed cumulative consumption was remarkably close, as the prediction was within 0.1% of the observed cumulative consumption. Feeding rates in the other three tanks ranged from 1.6% to 1.7% of walleye body weight per day, and bioenergetics model predictions of cumulative consumption over the 126-day experiment ranged between 11 and 15% less than the observed cumulative consumption. ?? 2008 Springer Science+Business Media B.V.

  14. UCVM: An Open Source Software Package for Querying and Visualizing 3D Velocity Models

    Science.gov (United States)

    Gill, D.; Small, P.; Maechling, P. J.; Jordan, T. H.; Shaw, J. H.; Plesch, A.; Chen, P.; Lee, E. J.; Taborda, R.; Olsen, K. B.; Callaghan, S.

    2015-12-01

    Three-dimensional (3D) seismic velocity models provide foundational data for ground motion simulations that calculate the propagation of earthquake waves through the Earth. The Southern California Earthquake Center (SCEC) has developed the Unified Community Velocity Model (UCVM) package for both Linux and OS X. This unique framework provides a cohesive way for querying and visualizing 3D models. UCVM v14.3.0, supports many Southern California velocity models including CVM-S4, CVM-H 11.9.1, and CVM-S4.26. The last model was derived from 26 full-3D tomographic iterations on CVM-S4. Recently, UCVM has been used to deliver a prototype of a new 3D model of central California (CCA) also based on full-3D tomographic inversions. UCVM was used to provide initial plots of this model and will be used to deliver CCA to users when the model is publicly released. Visualizing models is also possible with UCVM. Integrated within the platform are plotting utilities that can generate 2D cross-sections, horizontal slices, and basin depth maps. UCVM can also export models in NetCDF format for easy import into IDV and ParaView. UCVM has also been prototyped to export models that are compatible with IRIS' new Earth Model Collaboration (EMC) visualization utility. This capability allows for user-specified horizontal slices and cross-sections to be plotted in the same 3D Earth space. UCVM was designed to help a wide variety of researchers. It is currently being use to generate velocity meshes for many SCEC wave propagation codes, including AWP-ODC-SGT and Hercules. It is also used to provide the initial input to SCEC's CyberShake platform. For those interested in specific data points, the software framework makes it easy to extract P and S wave propagation speeds and other material properties from 3D velocity models by providing a common interface through which researchers can query earth models for a given location and depth. Also included in the last release was the ability to add small

  15. MEMS packaging

    CERN Document Server

    Hsu , Tai-Ran

    2004-01-01

    MEMS Packaging discusses the prevalent practices and enabling techniques in assembly, packaging and testing of microelectromechanical systems (MEMS). The entire spectrum of assembly, packaging and testing of MEMS and microsystems, from essential enabling technologies to applications in key industries of life sciences, telecommunications and aerospace engineering is covered. Other topics included are bonding and sealing of microcomponents, process flow of MEMS and microsystems packaging, automated microassembly, and testing and design for testing.The Institution of Engineering and Technology is

  16. Development of the CCP-200 mathematical model for Syzran CHPP using the Thermolib software package

    Science.gov (United States)

    Usov, S. V.; Kudinov, A. A.

    2016-04-01

    Simplified cycle diagram of the CCP-200 power generating unit of Syzran CHPP containing two gas turbines PG6111FA with generators, two steam recovery boilers KUP-110/15-8.0/0.7-540/200, and one steam turbine Siemens SST-600 (one-cylinder with two variable heat extraction units of 60/75 MW in heatextraction and condensing modes, accordingly) with S-GEN5-100 generators was presented. Results of experimental guarantee tests of the CCP-200 steam-gas unit are given. Brief description of the Thermolib application for the MatLab Simulink software package is given. Basic equations used in Thermolib for modeling thermo-technical processes are given. Mathematical models of gas-turbine plant, heat-recovery steam generator, steam turbine and integrated plant for power generating unit CCP-200 of Syzran CHPP were developed with the help of MatLab Simulink and Thermolib. The simulation technique at different ambient temperature values was used in order to get characteristics of the developed mathematical model. Graphic comparison of some characteristics of the CCP-200 simulation model (gas temperature behind gas turbine, gas turbine and combined cycle plant capacity, high and low pressure steam consumption and feed water consumption for high and low pressure economizers) with actual characteristics of the steam-gas unit received at experimental (field) guarantee tests at different ambient temperature are shown. It is shown that the chosen degrees of complexity, characteristics of the CCP-200 simulation model, developed by Thermolib, adequately correspond to the actual characteristics of the steam-gas unit received at experimental (field) guarantee tests; this allows considering the developed mathematical model as adequate and acceptable it for further work.

  17. The Laboratory Rat as an Animal Model for Osteoporosis Research

    OpenAIRE

    Lelovas, Pavlos P; Xanthos, Theodoros T.; Thoma, Sofia E; Lyritis, George P; Dontas, Ismene A

    2008-01-01

    Osteoporosis is an important systemic disorder, affecting mainly Caucasian women, with a diverse and multifactorial etiology. A large variety of animal species, including rodents, rabbits, dogs, and primates, have been used as animal models in osteoporosis research. Among these, the laboratory rat is the preferred animal for most researchers. Its skeleton has been studied extensively, and although there are several limitations to its similarity to the human condition, these can be overcome th...

  18. Modeller subjectivity in estimating pesticide parameters for leaching models using the same laboratory data set

    NARCIS (Netherlands)

    Boesten, J.J.T.I.

    2000-01-01

    User-dependent subjectivity in the process of testing pesticide leaching models is relevant because it may result in wrong interpretation of model tests. About 20 modellers used the same data set to test pesticide leaching models (one or two models per modeller). The data set included laboratory stu

  19. Modeller subjectivity in estimating pesticide parameters for leaching models using the same laboratory data set

    NARCIS (Netherlands)

    Boesten, J.J.T.I.

    2000-01-01

    User-dependent subjectivity in the process of testing pesticide leaching models is relevant because it may result in wrong interpretation of model tests. About 20 modellers used the same data set to test pesticide leaching models (one or two models per modeller). The data set included laboratory

  20. hydroPSO: A Versatile Particle Swarm Optimisation R Package for Calibration of Environmental Models

    Science.gov (United States)

    Zambrano-Bigiarini, M.; Rojas, R.

    2012-04-01

    Particle Swarm Optimisation (PSO) is a recent and powerful population-based stochastic optimisation technique inspired by social behaviour of bird flocking, which shares similarities with other evolutionary techniques such as Genetic Algorithms (GA). In PSO, however, each individual of the population, known as particle in PSO terminology, adjusts its flying trajectory on the multi-dimensional search-space according to its own experience (best-known personal position) and the one of its neighbours in the swarm (best-known local position). PSO has recently received a surge of attention given its flexibility, ease of programming, low memory and CPU requirements, and efficiency. Despite these advantages, PSO may still get trapped into sub-optimal solutions, suffer from swarm explosion or premature convergence. Thus, the development of enhancements to the "canonical" PSO is an active area of research. To date, several modifications to the canonical PSO have been proposed in the literature, resulting into a large and dispersed collection of codes and algorithms which might well be used for similar if not identical purposes. In this work we present hydroPSO, a platform-independent R package implementing several enhancements to the canonical PSO that we consider of utmost importance to bring this technique to the attention of a broader community of scientists and practitioners. hydroPSO is model-independent, allowing the user to interface any model code with the calibration engine without having to invest considerable effort in customizing PSO to a new calibration problem. Some of the controlling options to fine-tune hydroPSO are: four alternative topologies, several types of inertia weight, time-variant acceleration coefficients, time-variant maximum velocity, regrouping of particles when premature convergence is detected, different types of boundary conditions and many others. Additionally, hydroPSO implements recent PSO variants such as: Improved Particle Swarm

  1. Fullrmc, a rigid body Reverse Monte Carlo modeling package enabled with machine learning and artificial intelligence.

    Science.gov (United States)

    Aoun, Bachir

    2016-05-01

    A new Reverse Monte Carlo (RMC) package "fullrmc" for atomic or rigid body and molecular, amorphous, or crystalline materials is presented. fullrmc main purpose is to provide a fully modular, fast and flexible software, thoroughly documented, complex molecules enabled, written in a modern programming language (python, cython, C and C++ when performance is needed) and complying to modern programming practices. fullrmc approach in solving an atomic or molecular structure is different from existing RMC algorithms and software. In a nutshell, traditional RMC methods and software randomly adjust atom positions until the whole system has the greatest consistency with a set of experimental data. In contrast, fullrmc applies smart moves endorsed with reinforcement machine learning to groups of atoms. While fullrmc allows running traditional RMC modeling, the uniqueness of this approach resides in its ability to customize grouping atoms in any convenient way with no additional programming efforts and to apply smart and more physically meaningful moves to the defined groups of atoms. In addition, fullrmc provides a unique way with almost no additional computational cost to recur a group's selection, allowing the system to go out of local minimas by refining a group's position or exploring through and beyond not allowed positions and energy barriers the unrestricted three dimensional space around a group.

  2. SPICE Work Package 3: Modelling the Effects of Stratospheric Aerosol Geoengineering

    Science.gov (United States)

    Driscoll, Simon

    2015-04-01

    This talk presents the results of the SPICE Work Package 3. There is an obvious need for methods to verify the accuracy of geoengineering given no observations of a geoengineering programme. Accordingly, model ability in reproducing the observed dynamical response to volcanic eruptions is discussed using analysis of CMIP5 data and different configurations of the HadGEM2 model. With the HadGEM2-L60 model shown to be substantially better in reproducing the observed dynamical response to volcanic eruptions, simulations of GeoMIP's G4 scenario are performed. Simulated impacts of geoengineering are described, and asymmetries between the immediate onset and immediate cessation ('termination') of geoengineering are analysed. Whilst a rapid large increase in stratospheric sulphate aerosols (such as from volcanic eruptions) can cause substantial damage, most volcanic eruptions in general are not catastrophic. One may therefore suspect that an 'equal but opposite' change in radiative forcing from termination may therefore not be catastrophic, if the climatic response is simulated to be symmetric. HadGEM2 simulations reveal a substantially more rapid change in variables such as near-surface temperature and precipitation following termination than the onset, indicating that termination may be substantially more damaging and even catastrophic. Some suggestions for hemispherically asymmetric geoengineering have been proposed as a way to reduce Northern Hemisphere sea ice, for example, with lesser impacts on the rest of the climate. However, HadGEM2 simulations are performed and observations analysed following volcanic eruptions. Both indicate substantial averse consequences from hemispherically asymmetric loading of stratospheric loading on precipitation in the Sahelian region - a vulnerable region where drought has caused hundreds of thousands of deaths and created millions of refugees in the past.

  3. Numerical modeling and experimental validation of the acoustic transmission of aircraft's double-wall structures including sound package

    Science.gov (United States)

    Rhazi, Dilal

    In the field of aeronautics, reducing the harmful effects of acoustics constitutes a major concern at the international level and justifies the call for further research, particularly in Canada where aeronautics is a key economic sector, which operates in a context of global competition. Aircraft sidewall structure is usually of a double wall construction with a curved ribbed metallic skin and a lightweight composite or sandwich trim separated by a cavity filled with a noise control treatment. The latter is of a great importance in the transport industry, and continues to be of interest in many engineering applications. However, the insertion loss noise control treatment depends on the excitation of the supporting structure. In particular, Turbulent Boundary Layer is of interest to several industries. This excitation is difficult to simulate in laboratory conditions, given the prohibiting costs and difficulties associated with wind tunnel and in-flight tests. Numerical simulation is the only practical way to predict the response to such excitations and to analyze effects of design changes to the response to such excitation. Another kinds of excitations encountered in industrial are monopole, rain on the Roof and diffuse acoustic field. Deterministic methods can calculate in each point the spectral response of the system. Most known are numerical methods such as finite elements and boundary elements methods. These methods generally apply to the low frequency where modal behavior of the structure dominates. However, the high limit of calculation in frequency of these methods cannot be defined in a strict way because it is related to the capacity of data processing and to the nature of the studied mechanical system. With these challenges in mind, and with limitations of the main numerical codes on the market, the manufacturers have expressed the need for simple models immediately available as early as the stage of preliminary drafts. This thesis represents an attempt

  4. Flood Water Crossing: Laboratory Model Investigations for Water Velocity Reductions

    Directory of Open Access Journals (Sweden)

    Kasnon N.

    2014-01-01

    Full Text Available The occurrence of floods may give a negative impact towards road traffic in terms of difficulties in mobilizing traffic as well as causing damage to the vehicles, which later cause them to be stuck in the traffic and trigger traffic problems. The high velocity of water flows occur when there is no existence of objects capable of diffusing the water velocity on the road surface. The shape, orientation and size of the object to be placed beside the road as a diffuser are important for the effective flow attenuation of water. In order to investigate the water flow, a laboratory experiment was set up and models were constructed to study the flow velocity reduction. The velocity of water before and after passing through the diffuser objects was investigated. This paper focuses on laboratory experiments to determine the flow velocity of the water using sensors before and after passing through two best diffuser objects chosen from a previous flow pattern experiment.

  5. CYPROS - Cybernetic Program Packages

    Directory of Open Access Journals (Sweden)

    Arne Tyssø

    1980-10-01

    Full Text Available CYPROS is an interactive program system consisting of a number of special purpose packages for simulation, identification, parameter estimation and control system design. The programming language is standard FORTRAN IV and the system is implemented on a medium size computer system (Nord-10. The system is interactive and program control is obtained by the use of numeric terminals. Output is rapidly examined by extensive use of video colour graphics. The subroutines included in the packages are designed and documented according to standardization rules given by the SCL (Scandinavian Control Library organization. This simplifies the exchange of subroutines throughout the SCL system. Also, this makes the packages attractive for implementation by industrial users. In the simulation package, different integration methods are available and it can be easily used for off-line, as well as real time, simulation problems. The identification package consists of programs for single-input/single-output and multivariablc problems. Both transfer function models and state space models can be handled. Optimal test signals can be designed. The control package consists of programs based on multivariable time domain and frequency domain methods for analysis and design. In addition, there is a package for matrix and time series manipulation. CYPROS has been applied successfully to industrial problems of various kinds, and parts of the system have already been implemented on different computers in industry. This paper will, in some detail, describe the use and the contents of the packages and some examples of application will be discussed.

  6. The Marine Virtual Laboratory: enabling efficient ocean model configuration

    Directory of Open Access Journals (Sweden)

    P. R. Oke

    2015-11-01

    Full Text Available The technical steps involved in configuring a regional ocean model are analogous for all community models. All require the generation of a model grid, preparation and interpolation of topography, initial conditions, and forcing fields. Each task in configuring a regional ocean model is straight-forward – but the process of downloading and reformatting data can be time-consuming. For an experienced modeller, the configuration of a new model domain can take as little as a few hours – but for an inexperienced modeller, it can take much longer. In pursuit of technical efficiency, the Australian ocean modelling community has developed the Web-based MARine Virtual Laboratory (WebMARVL. WebMARVL allows a user to quickly and easily configure an ocean general circulation or wave model through a simple interface, reducing the time to configure a regional model to a few minutes. Through WebMARVL, a user is prompted to define the basic options needed for a model configuration, including the: model, run duration, spatial extent, and input data. Once all aspects of the configuration are selected, a series of data extraction, reprocessing, and repackaging services are run, and a "take-away bundle" is prepared for download. Building on the capabilities developed under Australia's Integrated Marine Observing System, WebMARVL also extracts all of the available observations for the chosen time-space domain. The user is able to download the take-away bundle, and use it to run the model of their choice. Models supported by WebMARVL include three community ocean general circulation models, and two community wave models. The model configuration from the take-away bundle is intended to be a starting point for scientific research. The user may subsequently refine the details of the model set-up to improve the model performance for the given application. In this study, WebMARVL is described along with a series of results from test cases comparing Web

  7. Environmental Modeling Packages for the MSTDCL TDP: Review and Recommendations (Trousses de Modelisation Environnementale Pour le PDT DCLTCM: Revue et Recommendations)

    Science.gov (United States)

    2009-09-01

    selection of acoustic model inputs, this can be much less than that required by some of the competing packages. The NUW package was also constructed with...1314, 1980. [5] R. T. Bachman , “Parameterization of Geoacoustic Properties”, San Diego, Cal., Scripps Institution of Oceanography, 1989 [6] E. B

  8. Design and implementation of a generalized laboratory data model

    Directory of Open Access Journals (Sweden)

    Nhan Mike

    2007-09-01

    Full Text Available Abstract Background Investigators in the biological sciences continue to exploit laboratory automation methods and have dramatically increased the rates at which they can generate data. In many environments, the methods themselves also evolve in a rapid and fluid manner. These observations point to the importance of robust information management systems in the modern laboratory. Designing and implementing such systems is non-trivial and it appears that in many cases a database project ultimately proves unserviceable. Results We describe a general modeling framework for laboratory data and its implementation as an information management system. The model utilizes several abstraction techniques, focusing especially on the concepts of inheritance and meta-data. Traditional approaches commingle event-oriented data with regular entity data in ad hoc ways. Instead, we define distinct regular entity and event schemas, but fully integrate these via a standardized interface. The design allows straightforward definition of a "processing pipeline" as a sequence of events, obviating the need for separate workflow management systems. A layer above the event-oriented schema integrates events into a workflow by defining "processing directives", which act as automated project managers of items in the system. Directives can be added or modified in an almost trivial fashion, i.e., without the need for schema modification or re-certification of applications. Association between regular entities and events is managed via simple "many-to-many" relationships. We describe the programming interface, as well as techniques for handling input/output, process control, and state transitions. Conclusion The implementation described here has served as the Washington University Genome Sequencing Center's primary information system for several years. It handles all transactions underlying a throughput rate of about 9 million sequencing reactions of various kinds per month and

  9. Laboratory Plasma Source as an MHD Model for Astrophysical Jets

    Science.gov (United States)

    Mayo, Robert M.

    1997-01-01

    The significance of the work described herein lies in the demonstration of Magnetized Coaxial Plasma Gun (MCG) devices like CPS-1 to produce energetic laboratory magneto-flows with embedded magnetic fields that can be used as a simulation tool to study flow interaction dynamic of jet flows, to demonstrate the magnetic acceleration and collimation of flows with primarily toroidal fields, and study cross field transport in turbulent accreting flows. Since plasma produced in MCG devices have magnetic topology and MHD flow regime similarity to stellar and extragalactic jets, we expect that careful investigation of these flows in the laboratory will reveal fundamental physical mechanisms influencing astrophysical flows. Discussion in the next section (sec.2) focuses on recent results describing collimation, leading flow surface interaction layers, and turbulent accretion. The primary objectives for a new three year effort would involve the development and deployment of novel electrostatic, magnetic, and visible plasma diagnostic techniques to measure plasma and flow parameters of the CPS-1 device in the flow chamber downstream of the plasma source to study, (1) mass ejection, morphology, and collimation and stability of energetic outflows, (2) the effects of external magnetization on collimation and stability, (3) the interaction of such flows with background neutral gas, the generation of visible emission in such interaction, and effect of neutral clouds on jet flow dynamics, and (4) the cross magnetic field transport of turbulent accreting flows. The applicability of existing laboratory plasma facilities to the study of stellar and extragalactic plasma should be exploited to elucidate underlying physical mechanisms that cannot be ascertained though astrophysical observation, and provide baseline to a wide variety of proposed models, MHD and otherwise. The work proposed herin represents a continued effort on a novel approach in relating laboratory experiments to

  10. Evaluation of a laboratory model of human head impact biomechanics.

    Science.gov (United States)

    Hernandez, Fidel; Shull, Peter B; Camarillo, David B

    2015-09-18

    This work describes methodology for evaluating laboratory models of head impact biomechanics. Using this methodology, we investigated: how closely does twin-wire drop testing model head rotation in American football impacts? Head rotation is believed to cause mild traumatic brain injury (mTBI) but helmet safety standards only model head translations believed to cause severe TBI. It is unknown whether laboratory head impact models in safety standards, like twin-wire drop testing, reproduce six degree-of-freedom (6DOF) head impact biomechanics that may cause mTBI. We compared 6DOF measurements of 421 American football head impacts to twin-wire drop tests at impact sites and velocities weighted to represent typical field exposure. The highest rotational velocities produced by drop testing were the 74th percentile of non-injury field impacts. For a given translational acceleration level, drop testing underestimated field rotational acceleration by 46% and rotational velocity by 72%. Primary rotational acceleration frequencies were much larger in drop tests (~100 Hz) than field impacts (~10 Hz). Drop testing was physically unable to produce acceleration directions common in field impacts. Initial conditions of a single field impact were highly resolved in stereo high-speed video and reconstructed in a drop test. Reconstruction results reflected aggregate trends of lower amplitude rotational velocity and higher frequency rotational acceleration in drop testing, apparently due to twin-wire constraints and the absence of a neck. These results suggest twin-wire drop testing is limited in modeling head rotation during impact, and motivate continued evaluation of head impact models to ensure helmets are tested under conditions that may cause mTBI. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. Numerical modelling of channel migration with application to laboratory rivers

    Institute of Scientific and Technical Information of China (English)

    Jian SUN; Bin-liang LIN; Hong-wei KUANG

    2015-01-01

    The paper presents the development of a morphological model and its application to experimental model rivers. The model takes into account the key processes of channel migration, including bed deformation, bank failure and wetting and drying. Secondary flows in bends play an important role in lateral sediment transport, which further affects channel migration. A new formula has been derived to predict the near-bed secondary flow speed, in which the magnitude of the speed is linked to the lateral water level gradient. Since only non-cohesive sediment is considered in the current study, the bank failure is modelled based on the concept of submerged angle of repose. The wetting and drying process is modelled using an existing method. Comparisons between the numerical model predictions and experimental observations for various discharges have been made. It is found that the model predicted channel planform and cross-sectional shapes agree generally well with the laboratory observations. A scenario analysis is also carried out to investigate the impact of secondary flow on the channel migration process. It shows that if the effect of secondary flow is ignored, the channel size in the lateral direction will be seriously underestimated.

  12. Three-dimensional integration and modeling a revolution in RF and wireless packaging

    CERN Document Server

    Lee, Jong-Hoon

    2007-01-01

    This book presents a step-by-step discussion of the 3D integration approach for the development of compact system-on-package (SOP) front-ends.Various examples of fully-integrated passive building blocks (cavity/microstip filters, duplexers, antennas), as well as a multilayer ceramic (LTCC) V-band transceiver front-end midule demonstrate the revolutionary effects of this approach in RF/Wireless packaging and multifunctional miniaturization.Designs covered are based on novel ideas and are presented for the first time for millimeterwave (60GHz) ultrabroadband wireless modules.Table of Contents: I

  13. An Ada Linear-Algebra Software Package Modeled After HAL/S

    Science.gov (United States)

    Klumpp, Allan R.; Lawson, Charles L.

    1990-01-01

    New avionics software written more easily. Software package extends Ada programming language to include linear-algebra capabilities similar to those of HAL/S programming language. Designed for such avionics applications as Space Station flight software. In addition to built-in functions of HAL/S, package incorporates quaternion functions used in Space Shuttle and Galileo projects and routines from LINPAK solving systems of equations involving general square matrices. Contains two generic programs: one for floating-point computations and one for integer computations. Written on IBM/AT personal computer running under PC DOS, v.3.1.

  14. An Ada Linear-Algebra Software Package Modeled After HAL/S

    Science.gov (United States)

    Klumpp, Allan R.; Lawson, Charles L.

    1990-01-01

    New avionics software written more easily. Software package extends Ada programming language to include linear-algebra capabilities similar to those of HAL/S programming language. Designed for such avionics applications as Space Station flight software. In addition to built-in functions of HAL/S, package incorporates quaternion functions used in Space Shuttle and Galileo projects and routines from LINPAK solving systems of equations involving general square matrices. Contains two generic programs: one for floating-point computations and one for integer computations. Written on IBM/AT personal computer running under PC DOS, v.3.1.

  15. A user's guide to the GoldSim/BLT-MS integrated software package:a low-level radioactive waste disposal performance assessment model.

    Energy Technology Data Exchange (ETDEWEB)

    Knowlton, Robert G.; Arnold, Bill Walter; Mattie, Patrick D.

    2007-03-01

    Sandia National Laboratories (Sandia), a U.S. Department of Energy National Laboratory, has over 30 years experience in the assessment of radioactive waste disposal and at the time of this publication is providing assistance internationally in a number of areas relevant to the safety assessment of radioactive waste disposal systems. In countries with small radioactive waste programs, international technology transfer program efforts are often hampered by small budgets, schedule constraints, and a lack of experienced personnel. In an effort to surmount these difficulties, Sandia has developed a system that utilizes a combination of commercially available software codes and existing legacy codes for probabilistic safety assessment modeling that facilitates the technology transfer and maximizes limited available funding. Numerous codes developed and endorsed by the United States Nuclear Regulatory Commission (NRC) and codes developed and maintained by United States Department of Energy are generally available to foreign countries after addressing import/export control and copyright requirements. From a programmatic view, it is easier to utilize existing codes than to develop new codes. From an economic perspective, it is not possible for most countries with small radioactive waste disposal programs to maintain complex software, which meets the rigors of both domestic regulatory requirements and international peer review. Therefore, revitalization of deterministic legacy codes, as well as an adaptation of contemporary deterministic codes, provides a credible and solid computational platform for constructing probabilistic safety assessment models. This document is a reference users guide for the GoldSim/BLT-MS integrated modeling software package developed as part of a cooperative technology transfer project between Sandia National Laboratories and the Institute of Nuclear Energy Research (INER) in Taiwan for the preliminary assessment of several candidate low

  16. Population stochastic modelling (PSM)--an R package for mixed-effects models based on stochastic differential equations.

    Science.gov (United States)

    Klim, Søren; Mortensen, Stig Bousgaard; Kristensen, Niels Rode; Overgaard, Rune Viig; Madsen, Henrik

    2009-06-01

    The extension from ordinary to stochastic differential equations (SDEs) in pharmacokinetic and pharmacodynamic (PK/PD) modelling is an emerging field and has been motivated in a number of articles [N.R. Kristensen, H. Madsen, S.H. Ingwersen, Using stochastic differential equations for PK/PD model development, J. Pharmacokinet. Pharmacodyn. 32 (February(1)) (2005) 109-141; C.W. Tornøe, R.V. Overgaard, H. Agersø, H.A. Nielsen, H. Madsen, E.N. Jonsson, Stochastic differential equations in NONMEM: implementation, application, and comparison with ordinary differential equations, Pharm. Res. 22 (August(8)) (2005) 1247-1258; R.V. Overgaard, N. Jonsson, C.W. Tornøe, H. Madsen, Non-linear mixed-effects models with stochastic differential equations: implementation of an estimation algorithm, J. Pharmacokinet. Pharmacodyn. 32 (February(1)) (2005) 85-107; U. Picchini, S. Ditlevsen, A. De Gaetano, Maximum likelihood estimation of a time-inhomogeneous stochastic differential model of glucose dynamics, Math. Med. Biol. 25 (June(2)) (2008) 141-155]. PK/PD models are traditionally based ordinary differential equations (ODEs) with an observation link that incorporates noise. This state-space formulation only allows for observation noise and not for system noise. Extending to SDEs allows for a Wiener noise component in the system equations. This additional noise component enables handling of autocorrelated residuals originating from natural variation or systematic model error. Autocorrelated residuals are often partly ignored in PK/PD modelling although violating the hypothesis for many standard statistical tests. This article presents a package for the statistical program R that is able to handle SDEs in a mixed-effects setting. The estimation method implemented is the FOCE(1) approximation to the population likelihood which is generated from the individual likelihoods that are approximated using the Extended Kalman Filter's one-step predictions.

  17. Modeling of secondary organic aerosol yields from laboratory chamber data

    Directory of Open Access Journals (Sweden)

    M. N. Chan

    2009-04-01

    Full Text Available A product-specific model for secondary organic aerosol (SOA formation and composition based on equilibrium gas-particle partitioning is evaluated. The model is applied to represent laboratory data on the ozonolysis of α-pinene under dry, dark, and low-NOx conditions in the presence of ammonium sulfate seed aerosol. Using five major identified products, the model is fit to the chamber data. From the optimal fitting, SOA oxygen-to-carbon (O/C and hydrogen-to-carbon (H/C ratios are modeled. The discrepancy between measured H/C ratios and those based on the oxidation products used in the model fitting suggests the potential importance of particle-phase reactions. Data fitting is also carried out using the volatility basis set, wherein oxidation products are parsed into volatility bins. The product-specific model is best used for an SOA precursor for which a substantial fraction of the aerosol-phase oxidation products has been identified.

  18. Radon transport in fractured soil. Laboratory experiments and modelling

    Energy Technology Data Exchange (ETDEWEB)

    Hoff, A.

    1997-10-01

    Radon (Rn-222) transport in fractured soil has been investigated by laboratory experiments and by modelling. Radon transport experiments have been performed with two sand columns (homogeneous and inhomogeneous) and one undisturbed clayey till column containing a net of preferential flow paths (root holes). A numerical model (the finite-element model FRACTRAN) and an analytic model (a pinhole model) have been applied in simulations if soil gas and radon transport in fractured soil. Experiments and model calculations are included in a discussion of radon entry rates into houses placed on fractured soil. The main conclusion is, that fractures does not in general alter transport of internally generated radon out of soil, when the pressure and flow conditions in the soil is comparable to the conditions prevailing under a house. This indicates the important result, that fractures in soil have no impact on radon entry into a house beyond that of an increased gas permeability, but a more thorough investigation of this subject is needed. Only in the case where the soil is exposed to large pressure gradients, relative to gradients induced by a house, may it be possible to observe effects of radon exchange between fractures and matrix. (au) 52 tabs., 60 ill., 5 refs.

  19. airGR: an R-package suitable for large sample hydrology presenting a suite of lumped hydrological models

    Science.gov (United States)

    Thirel, G.; Delaigue, O.; Coron, L.; Perrin, C.; Andreassian, V.

    2016-12-01

    Lumped hydrological models are useful and convenient tools for research, engineering and educational purposes. They propose catchment-scale representations of the precipitation-discharge relationship. Thanks to their limited data requirements, they can be easily implemented and run. With such models, it is possible to simulate a number of hydrological key processes over the catchment with limited structural and parametric complexity, typically evapotranspiration, runoff, underground losses, etc. The Hydrology Group at Irstea (Antony) has been developing a suite of rainfall-runoff models over the past 30 years with the main objectives of designing models as efficient as possible in terms of streamflow simulation, applicable to a wide range of catchments and having low data requirements. This resulted in a suite of models running at different time steps (from hourly to annual) applicable for various issues including water balance estimation, forecasting, simulation of impacts and scenario testing. Recently, Irstea has developed an easy-to-use R-package (R Core Team, 2015; Coron et al., 2016), called airGR, to make these models widely available. It includes: - the water balance annual GR1A (Mouehli et al., 2006), - the monthly GR2M (Mouehli, 2003) models, - three versions of the daily model, namely GR4J (Perrin et al., 2003), GR5J (Le Moine, 2008) and GR6J (Pushpalatha et al., 2011), - the hourly GR4H model (Mathevet, 2005), - a degree-day snow module CemaNeige (Valéry et al., 2014). The airGR package has been designed to facilitate the use by non-expert users and allow the addition of evaluation criteria, models or calibration algorithm selected by the end-user. Each model core is coded in FORTRAN to ensure low computational time. The other package functions (i.e. mainly the calibration algorithm and the efficiency criteria) are coded in R. The package is already used for educational purposes. It allows for convenient implementation of model inter-comparisons and

  20. Laboratory model of inner ear mechano-transduction

    Science.gov (United States)

    Mohammad, Ibrahim; Prodanovic, Srdjan; Laiacona, Danielle; Nam, Jong-Hoon; Kelley, Douglas

    2016-11-01

    A sound wave entering the mammalian ear displaces cochlear fluid, which in turn displaces hair-like organelles called stereocilia that act as acoustic sensors. Their incredible sensitivity is poorly understood, and probably depends on pre-amplification via fluid-structure interaction. In this talk, I will show how our lab uses a laboratory model to simulate this biological system to study the viscous coupling between the vibrating structures, cochlear fluid, and stereocilia. I will present measurements of modeled stereocilia gain and phase difference over a range of frequencies. Recent numerical simulations show that the sensor behaves as a high-pass filter with a gain plateau. However, our results show a peak in the gain. Further, I will show how the length of stereocilia affects gain. This project was supported by NIH NIDCD R01 DC014685.

  1. Characterization of integrated circuit packaging materials

    CERN Document Server

    Moore, Thomas

    1993-01-01

    Chapters in this volume address important characteristics of IC packages. Analytical techniques appropriate for IC package characterization are demonstrated through examples of the measurement of critical performance parameters and the analysis of key technological problems of IC packages. Issues are discussed which affect a variety of package types, including plastic surface-mount packages, hermetic packages, and advanced designs such as flip-chip, chip-on-board and multi-chip models.

  2. A comprehensive waste collection cost model applied to post-consumer plastic packaging waste

    NARCIS (Netherlands)

    Groot, J.J.; Bing, X.; Bos-Brouwers, H.E.J.; Bloemhof, J.M.

    2014-01-01

    Post-consumer plastic packaging waste (PPW) can be collected for recycling via source separation or post-separation. In source separation, households separate plastics from other waste before collection, whereas in post-separation waste is separated at a treatment centre after collection. There are

  3. Modelling of simultaneous two-sided migration into water and olive oil from nylon food packaging

    NARCIS (Netherlands)

    Stoffers, N.H.; Dekker, M.; Linssen, J.P.H.; Störmer, A.; Franz, R.; Boekel, van M.A.J.S.

    2005-01-01

    Nylon 6 and nylon 12 food packaging materials used as sausage casings are typically exposed to fatty food on one side and boiling water on the other during the cooking process. To simulate the migration behaviour under these conditions, a special migration cell was constructed and filled with olive

  4. Modelling of simultaneous two-sided migration into water and olive oil from nylon food packaging

    NARCIS (Netherlands)

    Stoffers, N.H.; Dekker, M.; Linssen, J.P.H.; Störmer, A.; Franz, R.; Boekel, van M.A.J.S.

    2005-01-01

    Nylon 6 and nylon 12 food packaging materials used as sausage casings are typically exposed to fatty food on one side and boiling water on the other during the cooking process. To simulate the migration behaviour under these conditions, a special migration cell was constructed and filled with olive

  5. A comprehensive waste collection cost model applied to post-consumer plastic packaging waste

    NARCIS (Netherlands)

    Groot, J.J.; Bing, X.; Bos-Brouwers, H.E.J.; Bloemhof, J.M.

    2014-01-01

    Post-consumer plastic packaging waste (PPW) can be collected for recycling via source separation or post-separation. In source separation, households separate plastics from other waste before collection, whereas in post-separation waste is separated at a treatment centre after collection. There are

  6. Analysis of mathematical models of Pseudomonas spp. growth in pallet-package pork stored at different temperatures.

    Science.gov (United States)

    Li, Miaoyun; Niu, Huimin; Zhao, Gaiming; Tian, Lu; Huang, Xianqing; Zhang, Jianwei; Tian, Wei; Zhang, Qiuhui

    2013-04-01

    Pseudomonas of pallet-packaged raw pork grown at 0, 5, 10, 15, 20 and 25°C has been studied in this paper. The modified Gompertz, Baranyi and Huang models were used for data fitting. Statistical criteria such as residual sum of squares, mean square error, Akaike's information criterion, and pseudo-R(2) were used to evaluate model performance. Results showed that there was an apparent decline in Pseudomonas growth at initial-storage phase at low temperatures. The modified Gompertz model outperformed the others at 5, 15, and 20°C, while Baranyi model was appropriate for 0 and 25°C. The Huang model was optimal at 10°C. No single model can give a consistently preferable goodness-of-fit for all growth data. The Gompertz model, with the smallest average values of RSS, AIC, MSE and the biggest pseudo-R(2) at all temperatures, is the most appropriate model to describe the growth of Pseudomonas of raw pork under pallet packaging. Copyright © 2012 Elsevier Ltd. All rights reserved.

  7. A simple landslide model at a laboratory scale

    Science.gov (United States)

    Atmajati, Elisabeth Dian; Yuliza, Elfi; Habil, Husni; Sadisun, Imam Ahmad; Munir, Muhammad Miftahul; Khairurrijal

    2017-07-01

    Landslide, which is one of the natural disasters that occurs frequently, often causes very adverse effects. Landslide early warning systems, which are installed at prone areas, measure physical parameters closely related to landslides and give warning signals indicating that landslides would occur. To determine the critical values of the measured physical parameters or test the early warning system itself, a laboratory scale model of a rotational landslide was developed. This rotational landslide model had a size of 250×45×40 cm3 and was equipped with soil moisture sensors, accelerometers, and automated measurement system. The soil moisture sensors were used to determine the water content in soil sample. The accelerometers were employed to detect movements in x-, y-, and z-direction. Therefore, the flow and rotational landslides were expected to be modeled and characterized. The developed landslide model could be used to evaluate the effects of slope, soil type, and water seepage on the incidence of landslides. The present experiment showed that the model can show the occurrence of landslides. The presence of water seepage made the slope crack. As the time went by, the crack became bigger. After evaluating the obtained characteristics, the occurred landslide was the flow type. This landslide occurred when the soil sample was in a saturated condition with water. The soil movements in x-, y-, and z-direction were also observed. Further experiments should be performed to realize the rotational landslide.

  8. Development of tube-packaged FBG strain sensor and application in the vibration experiment of submarine pipeline model

    Science.gov (United States)

    Ren, Liang; Li, Hong-Nan; Sun, Li; Li, Dong-Sheng

    2005-05-01

    Optical fiber sensors have received increasing attention in the fields of aeronautic and civil engineering for their superior ability of explosion proof, immunity to electromagnetic interference and high accuracy, especially fitting for measurement applications in harsh environment. In this paper, a novel FBG (fiber Bragg grating) strain sensor, which was packaged in a 1.2mm stainless steel tube by epoxy resin, was developed. Experiments were conducted on the universal material testing machine to calibrate its strain transferring characteristics. The sensor has the advantages of small size, high precision and flexible use, and demonstrates promising potentials. Ten of tube-packaged strain FBG sensors were applied in the vibration experiment of submarine pipeline model. The strain measured by FBG sensor agrees well with the electric resistance strain sensor.

  9. Verification of the karst flow model under laboratory controlled conditions

    Science.gov (United States)

    Gotovac, Hrvoje; Andric, Ivo; Malenica, Luka; Srzic, Veljko

    2016-04-01

    Karst aquifers are very important groundwater resources around the world as well as in coastal part of Croatia. They consist of extremely complex structure defining by slow and laminar porous medium and small fissures and usually fast turbulent conduits/karst channels. Except simple lumped hydrological models that ignore high karst heterogeneity, full hydraulic (distributive) models have been developed exclusively by conventional finite element and finite volume elements considering complete karst heterogeneity structure that improves our understanding of complex processes in karst. Groundwater flow modeling in complex karst aquifers are faced by many difficulties such as a lack of heterogeneity knowledge (especially conduits), resolution of different spatial/temporal scales, connectivity between matrix and conduits, setting of appropriate boundary conditions and many others. Particular problem of karst flow modeling is verification of distributive models under real aquifer conditions due to lack of above-mentioned information. Therefore, we will show here possibility to verify karst flow models under the laboratory controlled conditions. Special 3-D karst flow model (5.6*2.6*2 m) consists of concrete construction, rainfall platform, 74 piezometers, 2 reservoirs and other supply equipment. Model is filled by fine sand (3-D porous matrix) and drainage plastic pipes (1-D conduits). This model enables knowledge of full heterogeneity structure including position of different sand layers as well as conduits location and geometry. Moreover, we know geometry of conduits perforation that enable analysis of interaction between matrix and conduits. In addition, pressure and precipitation distribution and discharge flow rates from both phases can be measured very accurately. These possibilities are not present in real sites what this model makes much more useful for karst flow modeling. Many experiments were performed under different controlled conditions such as different

  10. Modelled Cost-Effectiveness of a Package Size Cap and a Kilojoule Reduction Intervention to Reduce Energy Intake from Sugar-Sweetened Beverages in Australia.

    Science.gov (United States)

    Crino, Michelle; Herrera, Ana Maria Mantilla; Ananthapavan, Jaithri; Wu, Jason H Y; Neal, Bruce; Lee, Yong Yi; Zheng, Miaobing; Lal, Anita; Sacks, Gary

    2017-09-06

    Interventions targeting portion size and energy density of food and beverage products have been identified as a promising approach for obesity prevention. This study modelled the potential cost-effectiveness of: a package size cap on single-serve sugar sweetened beverages (SSBs) >375 mL ( package size cap ), and product reformulation to reduce energy content of packaged SSBs ( energy reduction ). The cost-effectiveness of each intervention was modelled for the 2010 Australia population using a multi-state life table Markov model with a lifetime time horizon. Long-term health outcomes were modelled from calculated changes in body mass index to their impact on Health-Adjusted Life Years (HALYs). Intervention costs were estimated from a limited societal perspective. Cost and health outcomes were discounted at 3%. Total intervention costs estimated in AUD 2010 were AUD 210 million. Both interventions resulted in reduced mean body weight ( package size cap : 0.12 kg; energy reduction : 0.23 kg); and HALYs gained ( package size cap : 73,883; energy reduction : 144,621). Cost offsets were estimated at AUD 750.8 million ( package size cap ) and AUD 1.4 billion ( energy reduction ). Cost-effectiveness analyses showed that both interventions were "dominant", and likely to result in long term cost savings and health benefits. A package size cap and kJ reduction of SSBs are likely to offer excellent "value for money" as obesity prevention measures in Australia.

  11. Critical head, thickness of fine-grained deposit, and skeletal elastic storage arrays of the SUB package of the Central Valley Hydrologic Model

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This digital dataset defines the SUB package arrays for the model grid, critical head, thickness of fine-grained deposits, and skeletal-elastic-storage used in the...

  12. Demands placed on waste package performance testing and modeling by some general results on reliability analysis

    Energy Technology Data Exchange (ETDEWEB)

    Chesnut, D.A.

    1991-09-01

    Waste packages for a US nuclear waste repository are required to provide reasonable assurance of maintaining substantially complete containment of radionuclides for 300 to 1000 years after closure. The waiting time to failure for complex failure processes affecting engineered or manufactured systems is often found to be an exponentially-distributed random variable. Assuming that this simple distribution can be used to describe the behavior of a hypothetical single barrier waste package, calculations presented in this paper show that the mean time to failure (the only parameter needed to completely specify an exponential distribution) would have to be more than 10{sub 7} years in order to provide reasonable assurance of meeting this requirement. With two independent barriers, each would need to have a mean time to failure of only 10{sup 5} years to provide the same reliability. Other examples illustrate how multiple barriers can provide a strategy for not only achieving but demonstrating regulatory compliance.

  13. lumpR 2.0.0: an R package facilitating landscape discretisation for hillslope-based hydrological models

    Science.gov (United States)

    Pilz, Tobias; Francke, Till; Bronstert, Axel

    2017-08-01

    The characteristics of a landscape pose essential factors for hydrological processes. Therefore, an adequate representation of the landscape of a catchment in hydrological models is vital. However, many of such models exist differing, amongst others, in spatial concept and discretisation. The latter constitutes an essential pre-processing step, for which many different algorithms along with numerous software implementations exist. In that context, existing solutions are often model specific, commercial, or depend on commercial back-end software, and allow only a limited or no workflow automation at all. Consequently, a new package for the scientific software and scripting environment R, called lumpR, was developed. lumpR employs an algorithm for hillslope-based landscape discretisation directed to large-scale application via a hierarchical multi-scale approach. The package addresses existing limitations as it is free and open source, easily extendible to other hydrological models, and the workflow can be fully automated. Moreover, it is user-friendly as the direct coupling to a GIS allows for immediate visual inspection and manual adjustment. Sufficient control is furthermore retained via parameter specification and the option to include expert knowledge. Conversely, completely automatic operation also allows for extensive analysis of aspects related to landscape discretisation. In a case study, the application of the package is presented. A sensitivity analysis of the most important discretisation parameters demonstrates its efficient workflow automation. Considering multiple streamflow metrics, the employed model proved reasonably robust to the discretisation parameters. However, parameters determining the sizes of subbasins and hillslopes proved to be more important than the others, including the number of representative hillslopes, the number of attributes employed for the lumping algorithm, and the number of sub-discretisations of the representative hillslopes.

  14. IN-PACKAGE CHEMISTRY ABSTRACTION

    Energy Technology Data Exchange (ETDEWEB)

    E. Thomas

    2005-07-14

    This report was developed in accordance with the requirements in ''Technical Work Plan for Postclosure Waste Form Modeling'' (BSC 2005 [DIRS 173246]). The purpose of the in-package chemistry model is to predict the bulk chemistry inside of a breached waste package and to provide simplified expressions of that chemistry as a function of time after breach to Total Systems Performance Assessment for the License Application (TSPA-LA). The scope of this report is to describe the development and validation of the in-package chemistry model. The in-package model is a combination of two models, a batch reactor model, which uses the EQ3/6 geochemistry-modeling tool, and a surface complexation model, which is applied to the results of the batch reactor model. The batch reactor model considers chemical interactions of water with the waste package materials, and the waste form for commercial spent nuclear fuel (CSNF) waste packages and codisposed (CDSP) waste packages containing high-level waste glass (HLWG) and DOE spent fuel. The surface complexation model includes the impact of fluid-surface interactions (i.e., surface complexation) on the resulting fluid composition. The model examines two types of water influx: (1) the condensation of water vapor diffusing into the waste package, and (2) seepage water entering the waste package as a liquid from the drift. (1) Vapor-Influx Case: The condensation of vapor onto the waste package internals is simulated as pure H{sub 2}O and enters at a rate determined by the water vapor pressure for representative temperature and relative humidity conditions. (2) Liquid-Influx Case: The water entering a waste package from the drift is simulated as typical groundwater and enters at a rate determined by the amount of seepage available to flow through openings in a breached waste package.

  15. Comparison of Laboratory Experimental Data to XBeach Numerical Model Output

    Science.gov (United States)

    Demirci, Ebru; Baykal, Cuneyt; Guler, Isikhan; Sogut, Erdinc

    2016-04-01

    Coastal zones are living and constantly changing environments where both the natural events and the human-interaction results come into picture regarding to the shoreline behavior. Both the nature of the coastal zone and the human activities shape together the resultants of the interaction with oceans and coasts. Natural extreme events may result in the need of human interference, such as building coastal structures in order to prevent from disasters or any man-made structure throughout a coastline may affect the hydrodynamics and morphology in the nearshore. In order to understand and cope with this cycle of cause and effect relationship, the numerical models developed. XBeach is an open-source, 2DH, depth average numerical model including the hydrodynamic processes of short wave transformation (refraction, shoaling and breaking), long wave (infragravity wave) transformation (generation, propagation and dissipation), wave-induced setup and unsteady currents, as well as overwash and inundation and morphodynamic processes of bed load and suspended sediment transport, dune face avalanching, bed update and breaching (Roelvink et al., 2010). Together with XBeach numerical model, it is possible to both verify and visualize the resultant external effects to the initial shorelines in coastal zones. Recently, Baykal et al. (2015) modelled the long term morphology changes with XBeach near Kızılırmak river mouth consisting of one I-shaped and one Y-shaped groins. In order to investigate the nature of the shoreline and near shore hydrodynamic conditions and morphology, the five laboratory experiments are conducted in the Largescale Sediment Transport Facility at the U.S. Army Engineer Research and Development Center in order to be used to improve longshore sand transport relationships under the combined influence of waves and currents and the enhancement of predictive numerical models of beach morphology evolution. The first series of the experiments were aimed at

  16. Using ProModel as a simulation tools to assist plant layout design and planning: Case study plastic packaging factory

    Directory of Open Access Journals (Sweden)

    Pochamarn Tearwattanarattikal

    2008-01-01

    Full Text Available This study is about the application of a Simulation Model to assist decision making on expanding capacity and plant layout design and planning. The plant layout design concept is performed first to create the physical layouts then the simulation model used to test the capability of plant to meet various demand forecast scena. The study employed ProModel package as a tool, using the model to compare the performances in term of % utilization, characteristics of WIP and ability to meet due date. The verification and validation stages were perform before running the scenarios. The model runs daily production and then the capacity constraint resources defined by % utilization. The expanding capacity policy can be extra shift-working hours or increasing the number of machines. After expanding capacity solutions are found, the physical layout is selected based on the criterion of space available for WIP and easy flow of material.

  17. 工地试验室对于用EDTA滴定法快速测定灰剂量软件的实现%A New Software Package for Rapid Measurement of Lime Dose Using EDTA Titration in Field Laboratory

    Institute of Scientific and Technical Information of China (English)

    辛建丽; 徐桂香

    2012-01-01

    The key for road base construction quality control is to accurately measure and control the doses of cement and lime in cement stabilizer or lime stabilizer. Currently, the lime dose in field laboratory is estimated by human beings based on standard curve generated in EXCEL. Current practice is criticized for its low accuracy and long measurement time. We develop a new software package for rapid measurement of lime dose using EDTA titration. The software package is written in C# language and uses least - square fitting polynomial algorithm. The software package improves measurement accuracy and saves measurement time.%准确检测控制水泥或石灰稳定土中的水泥和石灰的剂量,是路面基层施工质量控制的关键.鉴于当前工地试验室对于灰剂量的现场检测大都是在EXCEL生成的标准曲线基础上采用人工估读得到.通过最小二乘法拟合多项式算法利用C#语言编程开发出适用于工地试验室用的EDTA滴定法快速测定灰剂量的软件.提高了该试验的检测精度并节省了时间.

  18. Subduction and exhumation of continental crust: insights from laboratory models

    Science.gov (United States)

    Bialas, Robert W.; Funiciello, Francesca; Faccenna, Claudio

    2011-01-01

    When slivers of continental crust and sediment overlying oceanic lithosphere enter a subduction zone, they may be scraped off at shallow levels, subducted to depths of up to 100-200 km and then exhumed as high pressure (HP) and ultra-high pressure (UHP) rocks, or subducted and recycled in the mantle. To investigate the factors that influence the behaviour of subducting slivers of continental material, we use 3-D dynamically consistent laboratory models. A laboratory analogue of a slab-upper mantle system is set up with two linearly viscous layers of silicone putty and glucose syrup in a tank. A sliver of continental material, also composed of silicone putty, overlies the subducting lithosphere, separated by a syrup detachment. The density of the sliver, viscosity of the detachment, geometry of the subducting system (attached plate versus free ridge) and dimensions of the sliver are varied in 34 experiments. By varying the density of the sliver and viscosity of the detachment, we can reproduce a range of sliver behaviour, including subduction, subduction and exhumation from various depths and offscraping. Sliver subduction and exhumation requires sufficient sliver buoyancy and a detachment that is strong enough to hold the sliver during initial subduction, but weak enough to allow adequate sliver displacement or detachment for exhumation. Changes to the system geometry alter the slab dip, subduction velocity, pattern of mantle flow and amount of rollback. Shallower slab dips with more trench rollback produce a mantle flow pattern that aids exhumation. Steeper slab dips allow more buoyancy force to be directed in the up-dip direction of the plane of the plate, and aide exhumation of subducted slivers. Slower subduction can also aide exhumation, but if slab dip is too steep or subduction too slow, the sliver will subduct to only shallow levels and not exhume. Smaller slivers are most easily subducted and exhumed and influenced by the mantle flow.

  19. Ground Contact Model for Mars Science Laboratory Mission Simulations

    Science.gov (United States)

    Raiszadeh, Behzad; Way, David

    2012-01-01

    The Program to Optimize Simulated Trajectories II (POST 2) has been successful in simulating the flight of launch vehicles and entry bodies on earth and other planets. POST 2 has been the primary simulation tool for the Entry Descent, and Landing (EDL) phase of numerous Mars lander missions such as Mars Pathfinder in 1997, the twin Mars Exploration Rovers (MER-A and MER-B) in 2004, Mars Phoenix lander in 2007, and it is now the main trajectory simulation tool for Mars Science Laboratory (MSL) in 2012. In all previous missions, the POST 2 simulation ended before ground impact, and a tool other than POST 2 simulated landing dynamics. It would be ideal for one tool to simulate the entire EDL sequence, thus avoiding errors that could be introduced by handing off position, velocity, or other fight parameters from one simulation to the other. The desire to have one continuous end-to-end simulation was the motivation for developing the ground interaction model in POST 2. Rover landing, including the detection of the postlanding state, is a very critical part of the MSL mission, as the EDL landing sequence continues for a few seconds after landing. The method explained in this paper illustrates how a simple ground force interaction model has been added to POST 2, which allows simulation of the entire EDL from atmospheric entry through touchdown.

  20. [Definition of "Safety and Hygiene Packages" as a management model for the Hospital Hygiene Service (HHS)].

    Science.gov (United States)

    Raponi, Matteo; Damiani, Gianfranco; Vincenti, Sara; Wachocka, Malgorzata; Boninti, Federica; Bruno, Stefania; Quaranta, Gianluigi; Moscato, Umberto; Boccia, Stefania; Ficarra, Maria Giovanna; Specchia, Maria Lucia; Posteraro, Brunella; Berloco, Filippo; Celani, Fabrizio; Ricciardi, Walter; Laurenti, Patrizia

    2014-01-01

    The purpose of this research is to identify and formalize the Hospital Hygiene Service activities and products, evaluating them in a cost accounting management view. The ultimate aim, is to evaluate the financial adverse events prevention impact, in an Hospital Hygiene Service management. A three step methodology based on affinity grouping activities, was employed. This methodology led us to identify 4 action areas, with 23 related productive processes, and 86 available safety packages. Owing to this new methodology, we was able to implement a systematic evaluation of the furnished services.

  1. Computer aided simulation for developing a simple model to predict cooling of packaged foods

    DEFF Research Database (Denmark)

    Christensen, Martin Gram; Feyissa, Aberham Hailu; Adler-Nissen, Jens

    A new equation to predict equilibrium temperatures for cooling operations of packaged foods has been deducted from the traditional 1st order solution to Fourier’s heat transfer equations. The equation is analytical in form and only requires measurable parameters, in form of area vs. volume ratio (A...... are too laborious or impossible to conduct. The deducted equation was tested for irregular geometries, unequal heat transfer and headspace restrictions. The new equation predicted equilibrium temperature curves of the simulated cooling with a low error (1.5°C for Fourier numbers below 0.3) and good...

  2. Unraveling topography around subduction zones from laboratory models

    Science.gov (United States)

    Husson, Laurent; Guillaume, Benjamin; Funiciello, Francesca; Faccenna, Claudio; Royden, Leigh H.

    2012-03-01

    The relief around subduction zones results from the interplay of dynamic processes that may locally exceed the (iso)static contributions. The viscous dissipation of the energy in and around subduction zones is capable of generating kilometer scale vertical ground movements. In order to evaluate dynamic topography in a self-consistent subduction system, we carried out a set of laboratory experiments, wherein the lithosphere and mantle are simulated by means of Newtonian viscous materials, namely silicone putty and glucose syrup. Models are kept in their most simple form and are made of negative buoyancy plates, of variable width and thickness, freely plunging into the syrup. The surface of the model and the top of the slab are scanned in three dimensions. A forebulge systematically emerges from the bending of the viscous plate, adjacent to the trench. With a large wavelength, dynamic pressure offsets the foreside and backside of the slab by ~ 500 m on average. The suction, that accompanies the vertical descent of the slab depresses the surface on both sides. At a distance equal to the half-width of the slab, the topographic depression amounts to ~ 500 m on average and becomes negligible at a distance that equals the width of the slab. In order to explore the impact of slab rollback on the topography, the trailing edge of the plates is alternatively fixed to (fixed mode) and freed from (free mode) the end wall of the tank. Both the pressure and suction components of the topography are ~ 30% lower in the free mode, indicating that slab rollback fosters the dynamic subsidence of upper plates. Our models are compatible with first order observations of the topography around the East Scotia, Tonga, Kermadec and Banda subduction zones, which exhibit anomalous depths of nearly 1 km as compared to adjacent sea floor of comparable age.

  3. Green Packaging Development. : A way to efficient, effective and more environmental friendly packaging solutions.

    OpenAIRE

    Mian Muhammad, Masoud

    2011-01-01

    Growing pressure on the packaging design to enhance the environmental and logistics performance of a packaging system stresses the packaging designers to search new design strategies that not only fulfill logistics requirements in the supply chain, but also reduce the CO 2emissions during the packaging life cycle. This thesis focuses on the packaging design process and suggests some improvements by considering its logistics performance and CO 2emissions. A Green packaging development model wa...

  4. Aqueous Corrosion Rates for Waste Package Materials

    Energy Technology Data Exchange (ETDEWEB)

    S. Arthur

    2004-10-08

    The purpose of this analysis, as directed by ''Technical Work Plan for: Regulatory Integration Modeling and Analysis of the Waste Form and Waste Package'' (BSC 2004 [DIRS 171583]), is to compile applicable corrosion data from the literature (journal articles, engineering documents, materials handbooks, or standards, and national laboratory reports), evaluate the quality of these data, and use these to perform statistical analyses and distributions for aqueous corrosion rates of waste package materials. The purpose of this report is not to describe the performance of engineered barriers for the TSPA-LA. Instead, the analysis provides simple statistics on aqueous corrosion rates of steels and alloys. These rates are limited by various aqueous parameters such as temperature (up to 100 C), water type (i.e., fresh versus saline), and pH. Corrosion data of materials at pH extremes (below 4 and above 9) are not included in this analysis, as materials commonly display different corrosion behaviors under these conditions. The exception is highly corrosion-resistant materials (Inconel Alloys) for which rate data from corrosion tests at a pH of approximately 3 were included. The waste package materials investigated are those from the long and short 5-DHLW waste packages, 2-MCO/2-DHLW waste package, and the 21-PWR commercial waste package. This analysis also contains rate data for some of the materials present inside the fuel canisters for the following fuel types: U-Mo (Fermi U-10%Mo), MOX (FFTF), Thorium Carbide and Th/U Carbide (Fort Saint Vrain [FSVR]), Th/U Oxide (Shippingport LWBR), U-metal (N Reactor), Intact U-Oxide (Shippingport PWR, Commercial), aluminum-based, and U-Zr-H (TRIGA). Analysis of corrosion rates for Alloy 22, spent nuclear fuel, defense high level waste (DHLW) glass, and Titanium Grade 7 can be found in other analysis or model reports.

  5. Laboratory and Numerical Modeling of Smoke Characteristics for Superfog Formation

    Science.gov (United States)

    Bartolome, C.; Lu, V.; Tsui, K.; Princevac, M.; Venkatram, A.; Mahalingam, S.; Achtemeier, G.; Weise, D.

    2011-12-01

    Land management techniques in wildland areas include prescribed fires to promote biodiversity and reduce risk of severe wildfires across the United States. Several fatal car pileups have been associated with smoke-related visibility reduction from prescribed burns. Such events have occurred in year 2000 on the interstate highways I-10 and I-95, 2001 on the I-4, 2006 on the I-95, and 2008 on the I-4 causing numerous fatalities, injuries, and damage to property. In some of the cases visibility reduction caused by smoke and fog combinations traveling over roadways have been reported to be less than 3 meters, defined as superfog. Our research focuses on delineating the conditions that lead to formation of the rare phenomena of superfog and creating a tool to enable land managers to effectively plan prescribed burns and prevent tragic events. It is hypothesized that the water vapor from combustion, live fuels, soil moisture, and ambient air condense onto the cloud condensation nuclei (CCN) particles emitted from low intensity smoldering fires. Physical and numerical modeling has been used to investigate these interactions. A physical model in the laboratory has been developed to characterize the properties of smoke resulting from smoldering pine needle litters at the PSW Forest Service in Riverside, CA. Temporal measurements of temperature, relative humidity, sensible heat flux, radiation heat flux, convective heat flux, particulate matter concentrations and visibilities have been measured for specific cases. The size distribution and number concentrations of the fog droplets formed inside the chamber by mixing cool dry and moist warm air masses to produce near superfog visibilities were measured by a Phase Doppler Particle Analyzer. Thermodynamic modeling of smoke and ambient air was conducted to estimate liquid water contents (LWC) available to condense into droplets and form significant reductions in visibility. The results show that LWC of less than 2 g m-3 can be

  6. A model for Bioinformatics training: the marine biological laboratory.

    Science.gov (United States)

    Yamashita, Grant; Miller, Holly; Goddard, Anthony; Norton, Cathy

    2010-11-01

    Many areas of science such as biology, medicine and oceanography are becoming increasingly data-rich and most programs that train scientists do not address informatics techniques or technologies that are necessary for managing and analysing large amounts of data. Educational resources for scientists in informatics are scarce, yet scientists need the skills and knowledge to work with informaticians and manage graduate students and post-docs in informatics projects. The Marine Biological Laboratory houses a world-renowned library and is involved in a number of informatics projects in the sciences. The MBL has been home to the National Library of Medicine's BioMedical Informatics Course for nearly two decades and is committed to educating scientists and other scholars in informatics. In an innovative, immersive learning experience, G.Y., a biologist and post-doc at Arizona State University, visited the Science Informatics Group at the MBL to learn first hand how informatics is done and how informatics teams work. Hands-on work with developers, systems administrators, librarians and other scientists provided an invaluable education in informatics and is a model for future science informatics training.

  7. Dose profile modeling of Idaho National Laboratory's active neutron interrogation laboratory.

    Science.gov (United States)

    Chichester, D L; Seabury, E H; Zabriskie, J M; Wharton, J; Caffrey, A J

    2009-06-01

    A new laboratory has been commissioned at Idaho National Laboratory for performing active neutron interrogation research and development. The facility is designed to provide radiation shielding for deuterium-tritium (DT) fusion (14.1 MeV) neutron generators (2 x 10(8) n/s), deuterium-deuterium (DD) fusion (2.5 MeV) neutron generators (1 x 10(7) n/s), and (252)Cf spontaneous fission neutron sources (6.96 x 10(7) n/s, 30 microg). Shielding at the laboratory is comprised of modular concrete shield blocks 0.76 m thick with tongue-in-groove features to prevent radiation streaming, arranged into one small and one large test vault. The larger vault is designed to allow operation of the DT generator and has walls 3.8m tall, an entrance maze, and a fully integrated electrical interlock system; the smaller test vault is designed for (252)Cf and DD neutron sources and has walls 1.9 m tall and a simple entrance maze. Both analytical calculations and numerical simulations were used in the design process for the building to assess the performance of the shielding walls and to ensure external dose rates are within required facility limits. Dose rate contour plots have been generated for the facility to visualize the effectiveness of the shield walls and entrance mazes and to illustrate the spatial profile of the radiation dose field above the facility and the effects of skyshine around the vaults.

  8. Intellectual package that uses knowledge of an object region and functional models in the planning of computations

    Energy Technology Data Exchange (ETDEWEB)

    Bukhshtab, Yu.A.; Gorlin, A.I.; Kamynin, S.S.; Koryagin, D.A.; Lyubimskiy, E.Z.

    1981-09-01

    Summary form only given, as follows. A method is proposed for constructing a system for filling a package of applied programs. The system is capable of automatic planning of computations, based on the use of knowledge of regarding the object region of the package and regarding the semantics of modules appearing in the functional filling of the package. An experimental package constructed in accordance with proposed principles is described, and an example of work with them is included.

  9. Empirical models for end-use properties prediction of LDPE: application in the flexible plastic packaging industry

    Directory of Open Access Journals (Sweden)

    Maria Carolina Burgos Costa

    2008-03-01

    Full Text Available The objective of this work is to develop empirical models to predict end use properties of low density polyethylene (LDPE resins as functions of two intrinsic properties easily measured in the polymers industry. The most important properties for application in the flexible plastic packaging industry were evaluated experimentally for seven commercial polymer grades. Statistical correlation analysis was performed for all variables and used as the basis for proper choice of inputs to each model output. Intrinsic properties selected for resin characterization are fluidity index (FI, which is essentially an indirect measurement of viscosity and weight average molecular weight (MW, and density. In general, models developed are able to reproduce and predict experimental data within experimental accuracy and show that a significant number of end use properties improve as the MW and density increase. Optical properties are mainly determined by the polymer morphology.

  10. Drop Test Results for the Combustion Engineering Model No. ABB-2901 Fuel Pellet Shipping Package

    Energy Technology Data Exchange (ETDEWEB)

    Mok, G; Hagler, L

    2002-06-01

    Steel cylindrical drums have been used for many years to transport radioactive materials. The radioactive material inserted into the drum cavity for shipping is usually restrained within its own container or containment vessel. For additional protection, the container is surrounded or supported by components made of impact-absorbent and/or thermal-insulation materials. The components are expected to protect the container and its radioactive contents under severe transportation conditions like free drops and fires. Due to its simplicity and convenience, bolted-ring drum closures are commonly used to close many drum packages. Because the structural integrity of the drum and drum closure often play a significant role in determining the package's ability to maintain sub-criticality, shielding, and containment of the radioactive contents, regulations require that the complete drum package be tested for safety performance. The structural integrity of the drum body is relatively simple to understand and analyze, whereas analyzing the integrity of the drum closure is not so simple. In summary, the drop test accomplished its mission. Because the lid and closure device separated from the drum body in the 30-ft 17.5{sup o} shallow-angle drop, the drop test confirmed that the common drum closure with a bolted ring is vulnerable to damage by a shallow-angle drop, even though the closure has been shown to survive much steeper-angle drops. The test program also demonstrated one of the mechanisms by which the shallow-angle drop opens the common bolted-ring drum closure. The separation of the drum lid and closure device from the drum body was initiated by a large outward buckling deformation of the lid and completed with minimal assistance by the round plywood boards behind the lid. The energy spent to complete the separation appeared to be only a small fraction of the total impact energy. Limited to only one test, the present test program could not explore all possible

  11. Lava-substrate heat transfer: Laboratory experiments and thermodynamic modeling

    Science.gov (United States)

    Rumpf, M.; Fagents, S. A.; Hamilton, C. W.; Wright, R.; Crawford, I.

    2012-12-01

    We have performed laboratory experiments and numerical modeling to investigate the heat transfer from a lava flow into various substrate materials, focusing on the effects of the differing thermophysical properties of substrate materials. Initial motivation for this project developed from the desire to understand the loss of solar wind volatiles embedded in lunar regolith deposits that were subsequently covered by a lava flow. The Moon lacks a significant atmosphere and magnetosphere, leaving the surface regolith exposed to bombardment by solar flare and solar wind particles, and by the cosmogenic products of galactic cosmic rays. Preservation of particle-rich regolith deposits may have occurred by the emplacement of an active lava flow on top of the regolith layer, provided the embedded particles survive heating by the lava. During future expeditions to the lunar surface, ancient regolith deposits could be sampled through surface drilling to extract the extra-lunar particles, revealing a history of the solar activity and galactic events not available on the Earth. This project also has important implications for terrestrial lava flows, particularly in the prediction of lava flow hazards. Lava erupted on Earth may be emplaced on various substrates, including solid lava rock, volcanic tephra, sands, soils, etc. The composition, grain size, consolidation, moisture content, etc. of these materials will vary greatly and have different effects on the cooling of the flow. Accounting for specific properties of the substrate could be an important improvement in lava flow models We have performed laboratory experiments in collaboration with the Department of Art and Art History at the University of Hawaii at Manoa in which ~5-6 kg of basalt, collected at Kilauea Volcano, Hawaii, is melted to ~1200 °C. The lava is poured into a device constructed of calcium silicate sheeting that has been filled with a solid or particulate substrate material and embedded with thermocouples

  12. WASTE CONTAINER AND WASTE PACKAGE PERFORMANCE MODELING TO SUPPORT SAFETY ASSESSMENT OF LOW AND INTERMEDIATE-LEVEL RADIOACTIVE WASTE DISPOSAL.

    Energy Technology Data Exchange (ETDEWEB)

    SULLIVAN, T.

    2004-06-30

    Prior to subsurface burial of low- and intermediate-level radioactive wastes, a demonstration that disposal of the wastes can be accomplished while protecting the health and safety of the general population is required. The long-time frames over which public safety must be insured necessitates that this demonstration relies, in part, on computer simulations of events and processes that will occur in the future. This demonstration, known as a Safety Assessment, requires understanding the performance of the disposal facility, waste containers, waste forms, and contaminant transport to locations accessible to humans. The objective of the coordinated research program is to examine the state-of-the-art in testing and evaluation short-lived low- and intermediate-level waste packages (container and waste form) in near surface repository conditions. The link between data collection and long-term predictions is modeling. The objective of this study is to review state-of-the-art modeling approaches for waste package performance. This is accomplished by reviewing the fundamental concepts behind safety assessment and demonstrating how waste package models can be used to support safety assessment. Safety assessment for low- and intermediate-level wastes is a complicated process involving assumptions about the appropriate conceptual model to use and the data required to support these models. Typically due to the lack of long-term data and the uncertainties from lack of understanding and natural variability, the models used in safety assessment are simplistic. However, even though the models are simplistic, waste container and waste form performance are often central to the case for making a safety assessment. An overview of waste container and waste form performance and typical models used in a safety assessment is supplied. As illustrative examples of the role of waste container and waste package performance, three sample test cases are provided. An example of the impacts of

  13. A Model for Designing Adaptive Laboratory Evolution Experiments

    DEFF Research Database (Denmark)

    LaCroix, Ryan A.; Palsson, Bernhard O.; Feist, Adam M.

    2017-01-01

    The occurrence of mutations is a cornerstone of the evolutionary theory of adaptation, capitalizing on the rare chance that a mutation confers a fitness benefit. Natural selection is increasingly being leveraged in laboratory settings for industrial and basic science applications. Despite...... increasing deployment, there are no standardized procedures available for designing and performing adaptive laboratory evolution (ALE) experiments. Thus, there is a need to optimize the experimental design, specifically for determining when to consider an experiment complete and for balancing outcomes...... adaptive laboratory evolution can achieve....

  14. Portobello Packaging

    National Research Council Canada - National Science Library

    Thomas Grose

    2010-01-01

    ...-based foams. Bayer earned dual degrees in mechanical engineering and product design in 2007 and, with classmate Gavin Mclntyre, started the company Ecovative Design to market his creation. EcoCradle, the company's organic packaging material, was named one of the top inventions of 2009 by Popular Science. Its insulation material, Greensulate, got a ...

  15. Repository environmental parameters and models/methodologies relevant to assessing the performance of high-level waste packages in basalt, tuff, and salt

    Energy Technology Data Exchange (ETDEWEB)

    Claiborne, H.C.; Croff, A.G.; Griess, J.C.; Smith, F.J.

    1987-09-01

    This document provides specifications for models/methodologies that could be employed in determining postclosure repository environmental parameters relevant to the performance of high-level waste packages for the Basalt Waste Isolation Project (BWIP) at Richland, Washington, the tuff at Yucca Mountain by the Nevada Test Site, and the bedded salt in Deaf Smith County, Texas. Guidance is provided on the identify of the relevant repository environmental parameters; the models/methodologies employed to determine the parameters, and the input data base for the models/methodologies. Supporting studies included are an analysis of potential waste package failure modes leading to identification of the relevant repository environmental parameters, an evaluation of the credible range of the repository environmental parameters, and a summary of the review of existing models/methodologies currently employed in determining repository environmental parameters relevant to waste package performance. 327 refs., 26 figs., 19 tabs.

  16. Spallation Source Modelling for an ADS Using the MCNPX and GEANT4 Packages for Sensitivity Analysis of Reactivity

    Science.gov (United States)

    Antolin, M. Q.; Marinho, F.; Palma, D. A. P.; Martinez, A. S.

    2014-04-01

    A simulation for the time evolution of the MYRRHA conceptual reactor was developed. The SERPENT code was used to simulate the nuclear fuel depletion and the spallation source which drives the system was simulated using both MCNPX and GEANT4 packages. The obtained results for the neutron energy spectrum from the spallation are coherent with each other and were used as input for the SERPENT code which simulated a constant power operation regime. The obtained results show that the criticality of the system is not sensitive to the spallation models employed and only relative small deviations with respect to the inverse kinetic model coming from the point kinetic equations proposed by Gandini were observed.

  17. Fitting HIV Prevalence 1981 Onwards for Three Indian States Using the Goals Model and the Estimation and Projection Package

    Science.gov (United States)

    Bhatnagar, Tarun; Dutta, Tapati; Stover, John; Godbole, Sheela; Sahu, Damodar; Boopathi, Kangusamy; Bembalkar, Shilpa; Singh, Kh. Jitenkumar; Goyal, Rajat; Pandey, Arvind; Mehendale, Sanjay M.

    2016-01-01

    Models are designed to provide evidence for strategic program planning by examining the impact of different interventions on projected HIV incidence. We employed the Goals Model to fit the HIV epidemic curves in Andhra Pradesh, Maharashtra and Tamil Nadu states of India where HIV epidemic is considered to have matured and in a declining phase. Input data in the Goals Model consisted of demographic, epidemiological, transmission-related and risk group wise behavioral parameters. The HIV prevalence curves generated in the Goals Model for each risk group in the three states were compared with the epidemic curves generated by the Estimation and Projection Package (EPP) that the national program is routinely using. In all the three states, the HIV prevalence trends for high-risk populations simulated by the Goals Model matched well with those derived using state-level HIV surveillance data in the EPP. However, trends for the low- and medium-risk populations differed between the two models. This highlights the need to generate more representative and robust data in these sub-populations and consider some structural changes in the modeling equation and parameters in the Goals Model to effectively use it to assess the impact of future strategies of HIV control in various sub-populations in India at the sub-national level. PMID:27711212

  18. Verification of a laboratory-based dilation model for in situ conditions using continuum models

    Institute of Scientific and Technical Information of China (English)

    G. Walton; M.S. Diederichs; L.R. Alejano; J. Arzúa

    2014-01-01

    With respect to constitutive models for continuum modeling applications, the post-yield domain re-mains the area of greatest uncertainty. Recent studies based on laboratory testing have led to the development of a number of models for brittle rock dilation, which account for both the plastic shear strain and confining stress dependencies of this phenomenon. Although these models are useful in providing an improved understanding of how dilatancy evolves during a compression test, there has been relatively little work performed examining their validity for modeling brittle rock yield in situ. In this study, different constitutive models for rock dilation are reviewed and then tested, in the context of a number of case studies, using a continuum finite-difference approach (FLAC). The uncertainty associated with the modeling of brittle fracture localization is addressed, and the overall ability of mobilized dilation models to replicate in situ deformation measurements and yield patterns is evaluated.

  19. A controllable laboratory stock market for modeling real stock markets

    Science.gov (United States)

    An, Kenan; Li, Xiaohui; Yang, Guang; Huang, Jiping

    2013-10-01

    Based on the different research approaches, econophysics can be divided into three directions: empirical econophysics, computational econophysics, and experimental econophysics. Because empirical econophysics lacks controllability that is needed to study the impacts of different external conditions and computational econophysics has to adopt artificial decision-making processes that are often deviated from those of real humans, experimental econophysics tends to overcome these problems by offering controllability and using real humans in laboratory experiments. However, to our knowledge, the existing laboratory experiments have not convincingly reappeared the stylized facts (say, scaling) that have been revealed for real economic/financial markets by econophysicists. A most important reason is that in these experiments, discrete trading time makes these laboratory markets deviated from real markets where trading time is naturally continuous. Here we attempt to overcome this problem by designing a continuous double-auction stock-trading market and conducting several human experiments in laboratory. As an initial work, the present artificial financial market can reproduce some stylized facts related to clustering and scaling. Also, it predicts some other scaling in human behavior dynamics that is hard to achieve in real markets due to the difficulty in getting the data. Thus, it becomes possible to study real stock markets by conducting controlled experiments on such laboratory stock markets producing high frequency data.

  20. CH Packaging Program Guidance

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2009-06-01

    The purpose of this document is to provide the technical requirements for preparation for use, operation, inspection, and maintenance of a Transuranic Package Transporter Model II (TRUPACT-II), a HalfPACT shipping package, and directly related components. This document complies with the minimum requirements as specified in the TRUPACT-II Safety Analysis Report for Packaging (SARP), HalfPACT SARP, and U.S. Nuclear Regulatory Commission (NRC) Certificates of Compliance (C of C) 9218 and 9279, respectively. In the event of a conflict between this document and the SARP or C of C, the C of C shall govern. The C of Cs state: "each package must be prepared for shipment and operated in accordance with the procedures described in Chapter 7.0, Operating Procedures, of the application." They further state: "each package must be tested and maintained in accordance with the procedures described in Chapter 8.0, Acceptance Tests and Maintenance Program of the Application." Chapter 9.0 of the SARP charges the U.S. Department of Energy (DOE) or the Waste Isolation Pilot Plant (WIPP) management and operating (M&O) contractor with assuring packaging is used in accordance with the requirements of the C of C. Because the packaging is NRC-approved, users need to be familiar with Title 10 Code of Federal Regulations (CFR) §71.8. Any time a user suspects or has indications that the conditions of approval in the C of C were not met, the Carlsbad Field Office (CBFO) shall be notified immediately. The CBFO will evaluate the issue and notify the NRC if required. In accordance with 10 CFR Part 71, certificate holders, packaging users, and contractors or subcontractors who use, design, fabricate, test, maintain, or modify the packaging shall post copies of (1) 10 CFR Part 21 regulations, (2) Section 206 of the Energy Reorganization Act of 1974, and (3) NRC Form 3, Notice to Employees. These documents must be posted in a conspicuous location where the activities subject to these regulations are

  1. CH Packaging Program Guidance

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2008-09-11

    The purpose of this document is to provide the technical requirements for preparation for use, operation, inspection, and maintenance of a Transuranic Package Transporter Model II (TRUPACT-II), a HalfPACT shipping package, and directly related components. This document complies with the minimum requirements as specified in the TRUPACT-II Safety Analysis Report for Packaging (SARP), HalfPACT SARP, and U.S. Nuclear Regulatory Commission (NRC) Certificates of Compliance (C of C) 9218 and 9279, respectively. In the event of a conflict between this document and the SARP or C of C, the C of C shall govern. The C of Cs state: "each package must be prepared for shipment and operated in accordance with the procedures described in Chapter 7.0, Operating Procedures, of the pplication." They further state: "each package must be tested and maintained in accordance with the procedures described in Chapter 8.0, Acceptance Tests and Maintenance Program of the Application." Chapter 9.0 of the SARP charges the U.S. Department of Energy (DOE) or the Waste Isolation Pilot Plant (WIPP) management and operating (M&O) contractor with assuring packaging is used in accordance with the requirements of the C of C. Because the packaging is NRC-approved, users need to be familiar with Title 10 Code of Federal Regulations (CFR) §71.8. Any time a user suspects or has indications that the conditions of approval in the C of C were not met, the Carlsbad Field Office (CBFO) shall be notified immediately. The CBFO will evaluate the issue and notify the NRC if required. In accordance with 10 CFR Part 71, certificate holders, packaging users, and contractors or subcontractors who use, design, fabricate, test, maintain, or modify the packaging shall post copies of (1) 10 CFR Part 21 regulations, (2) Section 206 of the Energy Reorganization Act of 1974, and (3) NRC Form 3, Notice to Employees. These documents must be posted in a conspicuous location where the activities subject to these regulations are

  2. Seafood Packaging

    Science.gov (United States)

    1996-01-01

    NASA's Technology Transfer Office at Stennis Space Center worked with a New Orleans seafood packaging company to develop a container to improve the shipping longevity of seafood, primarily frozen and fresh fish, while preserving the taste. A NASA engineer developed metalized heat resistant polybags with thermal foam liners using an enhanced version of the metalized mylar commonly known as 'space blanket material,' which was produced during the Apollo era.

  3. Modelling growth of Escherichia coli O157:H7 in fresh-cut lettuce submitted to commercial process conditions: chlorine washing and modified atmosphere packaging.

    Science.gov (United States)

    Posada-Izquierdo, Guiomar D; Pérez-Rodríguez, Fernando; López-Gálvez, Francisco; Allende, Ana; Selma, María V; Gil, María I; Zurera, Gonzalo

    2013-04-01

    Fresh-cut iceberg lettuce inoculated with Escherichia coli O157:H7 was submitted to chlorine washing (150 mg/mL) and modified atmosphere packaging on laboratory scale. Populations of E. coli O157:H7 were assessed in fresh-cut lettuce stored at 4, 8, 13 and 16 °C using 6-8 replicates in each analysis point in order to capture experimental variability. The pathogen was able to grow at temperatures ≥8 °C, although at low temperatures, growth data presented a high variability between replicates. Indeed, at 8 °C after 15 days, some replicates did not show growth while other replicates did present an increase. A growth primary model was fitted to the raw growth data to estimate lag time and maximum growth rate. The prediction and confidence bands for the fitted growth models were estimated based on Monte-Carlo method. The estimated maximum growth rates (log cfu/day) corresponded to 0.14 (95% CI: 0.06-0.31), 0.55 (95% CI: 0.17-1.20) and 1.43 (95% CI: 0.82-2.15) for 8, 13 and 16 °C, respectively. A square-root secondary model was satisfactorily derived from the estimated growth rates (R(2) > 0.80; Bf = 0.97; Af = 1.46). Predictive models and data obtained in this study are intended to improve quantitative risk assessment studies for E. coli O157:H7 in leafy green products. Copyright © 2012. Published by Elsevier Ltd.

  4. Use of food and packaging model matrices to investigate the antioxidant properties of biorefinery grass lignins.

    Science.gov (United States)

    Aguié-Béghin, Véronique; Foulon, Laurence; Soto, Paola; Crônier, David; Corti, Elena; Legée, Frédéric; Cézard, Laurent; Chabbert, Brigitte; Maillard, Marie-Noëlle; Huijgen, Wouter J J; Baumberger, Stéphanie

    2015-11-18

    The antioxidant properties of grass lignins recovered from an alkaline industrial process and from different ethanol organosolv pretreatment processes were compared using two types of tests: (i) classical radical 2,2'-diphenyl-1-picrylhydrazyl (DPPH(•)) scavenging tests in dioxane/water or ethanol and (ii) tests involving multiphasic systems (lipid dispersion in water or cellulose film suspended in ethanol). These multiphasic systems were representative of food and packaging matrices in view of high-value applications. All lignins, in solution or in the film, effectively scavenged radicals. Moreover, they were competitive with a food commercial rosemary extract to protect linoleic acid against oxidation. Whereas the DPPH(•) test in dioxane was not discriminant, differences appeared between lignins when the test was performed in ethanol or with the multiphasic systems. Moreover, radical scavenging activity was preserved in the film even after its immersion in ethanol. Structural analysis of lignins revealed that low-molar-mass phenolics, namely p-hydroxycinnamic acids and lignin depolymerization products, governed lignin antioxidant properties in the multiphasic systems.

  5. A laboratory scale model of abrupt ice-shelf disintegration

    Science.gov (United States)

    Macayeal, D. R.; Boghosian, A.; Styron, D. D.; Burton, J. C.; Amundson, J. M.; Cathles, L. M.; Abbot, D. S.

    2010-12-01

    An important mode of Earth’s disappearing cryosphere is the abrupt disintegration of ice shelves along the Peninsula of Antarctica. This disintegration process may be triggered by climate change, however the work needed to produce the spectacular, explosive results witnessed with the Larsen B and Wilkins ice-shelf events of the last decade comes from the large potential energy release associated with iceberg capsize and fragmentation. To gain further insight into the underlying exchanges of energy involved in massed iceberg movements, we have constructed a laboratory-scale model designed to explore the physical and hydrodynamic interactions between icebergs in a confined channel of water. The experimental apparatus consists of a 2-meter water tank that is 30 cm wide. Within the tank, we introduce fresh water and approximately 20-100 rectangular plastic ‘icebergs’ having the appropriate density contrast with water to mimic ice. The blocks are initially deployed in a tight pack, with all blocks arranged in a manner to represent the initial state of an integrated ice shelf or ice tongue. The system is allowed to evolve through time under the driving forces associated with iceberg hydrodynamics. Digitized videography is used to quantify how the system of plastic icebergs evolves between states of quiescence to states of mobilization. Initial experiments show that, after a single ‘agitator’ iceberg begins to capsize, an ‘avalanche’ of capsizing icebergs ensues which drives horizontal expansion of the massed icebergs across the water surface, and which stimulates other icebergs to capsize. A surprise initially evident in the experiments is the fact that the kinetic energy of the expanding mass of icebergs is only a small fraction of the net potential energy released by the rearrangement of mass via capsize. Approximately 85 - 90 % of the energy released by the system goes into water motion modes, including a pervasive, easily observed seich mode of the tank

  6. The Effective Teaching of Packaging Design Based on Laboratory Mode%基于实验室模式的包装设计有效教学初探

    Institute of Scientific and Technical Information of China (English)

    李帅; 周作好

    2011-01-01

    There are many deficiencies in the current packaging design teaching such as student' s psychology, syllabus, shortage of teachers and teaching facilities, contradiction between the outcome of packaging design and the market supply and demand. Therefore, it is necessary to explore the effective teaching modes by the way of starting laboratory mode of teaching, rene-wing teaching ideas, standardizing the design teaching, developing theory and practice synchronously and upgrading the teaching facilities.%现行包装设计专业教学仍存在诸多不足:包装设计专业学生“求学心态”的不健康;教学大纲“面全而不精”;师资力量的薄弱与教学设备的缺乏问题;包装设计教学成果与市场需求的供求矛盾。为此,有目的地启用实验室模式教学,更新教学观念,规范设计教学,确定新的教学目标;完善教学设备,理论与实践同步发展;积极探索有效教学的新模式。

  7. microbiological quality of re-packaged sweets sold in metropolitan ...

    African Journals Online (AJOL)

    DR. AMINU

    simple packaging or re-packaging operations can bring ... into a desiccator for cooling to room temperature. The ... Range of bacterial count (cfu/g). Fungal count. (cfu/g). Range of fungal ..... Cheesbrough, M. (2002): Medical laboratory manual.

  8. Applicability of an Arrhenius Model for the Combined Effect of Temperature and CO2 Packaging on the Spoilage Microflora of Fish

    Science.gov (United States)

    Koutsoumanis, Konstantinos P.; Taoukis, Petros S.; Drosinos, Eleftherios H.; Nychas, George-John E.

    2000-01-01

    The temperature behavior of the natural microflora on the Mediterranean fish red mullet (Mullus barbatus) was examined as a case study. The growth of the spoilage bacteria Pseudomonas spp., Shewanella putrefaciens, Brochothrix thermosphacta, and lactic acid bacteria was modeled as a function of temperature and the concentration of carbon dioxide in modified atmosphere packaging. Combined models were developed and comparatively assessed based on polynomial, Belehradek, and Arrhenius equations. The activation energy parameter of the Arrhenius model, EA, was independent of the packaging atmosphere and ranged from 75 to 85 kJ/mol for the different bacteria, whereas the preexponential constant decreased exponentially with the packaging CO2 concentration. We evaluated the applicability of the models developed by using experimental bacterial growth rates obtained from 42 independent experiments performed with three Mediterranean fish species and growth rates predicted from the models under the same temperature and packaging conditions. The accuracy factor and bias factor were used as statistical tools for evaluation, and the developed Arrhenius model and the Belehradek model were judged satisfactory overall. PMID:10919817

  9. Remaining Sites Verification Package for the 100-F-52, 146-FR Radioecology and Aquatic Biology Laboratory Soil, Waste Site Reclassification Form 2008-022

    Energy Technology Data Exchange (ETDEWEB)

    J. M. Capron

    2008-06-27

    The 100-F-52 waste site consisted of the soil under and around the former 146-FR Radioecology and Aquatic Biology Laboratory. The laboratory was used for studies of the effects of pre-reactor and post-reactor process water on fish eggs, young fish, and other small river creatures of interest. In accordance with this evaluation, the confirmatory sampling results support a reclassification of this site to No Action. The current site conditions achieve the remedial action objectives and the corresponding remedial action goals established in the Remaining Sites ROD. The results of confirmatory sampling show that residual contaminant concentrations do not preclude any future uses and allow for unrestricted use of shallow zone soils. The results also demonstrate that residual contaminant concentrations are protective of groundwater and the Columbia River.

  10. NOx abatement by fuel-lean reburning: Laboratory combustor and pilot-scale package boiler results. Report for June 1995--December 1997

    Energy Technology Data Exchange (ETDEWEB)

    Miller, C.A.; Touati, A.D.; Becker, J.; Wendt, J.O.L.

    1997-12-31

    The paper discusses two experimental studies related to the abatement of nitrogen oxides (NOx) by fuel-lean reburning. First, systematic tests in a 17-kW down-flow laboratory combustor, in which nitric oxide (NO) in the oxidant was destroyed in long, axial, methane/air diffusion flames, showed that substantial reduction of NO was possible under overall fuel-lean conditions.

  11. Antioxidant BHT Modelling Migration from Food Packaging of High Density Polyethylene Plastics into the Food Simulant

    Directory of Open Access Journals (Sweden)

    Chi Haitao

    2015-09-01

    Full Text Available Made of High Density Polyethylene (HDPE films containing antioxidant 2, 6-di-tert-butyl-p-cresol (BHT, film samples were manufactured by plastic extrusion equipment, 95% ethanol aqueous solution simulating liquid was used for stimulant, using High Performance Liquid Chromatography (HPLC for the long-term migration test of 4 kinds of HDPE films containing different concentrations of antioxidant BHT. The migration data were processed by using Weibull model and then the migration model was specific under experimental conditions. Migration model was setup using the migrating data by Weibull model to fitting real experimental data. Using empirical formula reported FDA model formula and the diffusion coefficient constant D, calculated by the FDA model. Two kinds of model numerical after compared according to FDA model transfer numerical literature that is far lower than the actual test migration value. According to the actual test migration value, Weibull model numerical and experimental tests that the migration software fitting values are consistent.

  12. Interview: partnering with the industry: the Olympic laboratory model.

    Science.gov (United States)

    Cowan, David A; Barker, Campbell P

    2012-07-01

    David A Cowan and Campbell P Barker speak to Ryan De Vooght-Johnson at Bioanalysis in May 2012 about the partnership between industry and academia for the setup and running of the doping-control laboratory for the London 2012 Olympic Games. David A Cowan is Director of the London 2012 anti-doping laboratory as well as Director of the King's College London Drug Control Centre, the UK's only WADA-accredited anti-doping laboratory, and Head of the Department of Forensic Science and Drug Monitoring. Cowan co-founded the Drug Control Centre in 1978 and became its Director in 1990. He has published extensively in the field of pharmaceutical analysis, especially as it relates to detecting drug administration in sport, and was awarded a personal chair in pharmaceutical toxicology in 1996. Cowan became Head of the Department of Forensic Science and Drug Monitoring at King's College London in 2002. He has served on a number of national and international committees, including the Council of Europe Working Party Investigating Drug Abuse in Sport that led to the first World Anti-Doping Convention, the Laboratory Representative on the International Olympic Committee's Medical Commission, and WADA's Laboratory Accreditation Subcommittee. He is a member of the Crippen Club for Distinguished Toxicologists. In 1998 he was awarded the IOC Trophy for Sport Ethics by the BOA. He was a founding member of the World Association of Anti-Doping Scientists and became its first President serving on its Executive Board between 2001 and 2004. He was a Visiting Laboratory Director at the Salt Lake City Winter Olympic Games 2002, where the first novel erythropoiesis-stimulating protein (NESP) positive was discovered. He was also a senior advisory scientist at both the Turin Winter Olympic Games in 2006 and the Beijing Olympic Games in 2008. He was also a member of the IOC Medical Commission for the Sydney Olympic Games in 2000 and the Vancouver Winter Olympic Games in 2010. The Drug Control

  13. An Application of the Thermal Network Method to the Thermal Analysis of Multichip Packages (Proposal of a Simple Thermal Analysis Model)

    Science.gov (United States)

    Fukuoka, Yoshitaka; Ishizuka, Masaru

    1989-09-01

    In recent years, electronic circuits have been required to be smaller and lighter and to have greater complexity, more multifunctions and higher reliability. High-density multichip packaging technology has been used in order to meet these requirements. The higher the density scale, the larger the power dissipation per unit area will become. Therefore, thermal analysis becomes one of the most important design factors. However, the multichip package heat transport mode is very complex and its treatment is tedious and time consuming. This paper describes an application of the thermal network method and proposes a simple thermal analysis model for the thermal analysis of multichip packages as a preliminary thermal design tool. As a result, the validity of the thermal network method and the simple thermal analysis model can be confirmed.

  14. CH Packaging Program Guidance

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2007-12-13

    The purpose of this document is to provide the technical requirements for preparation for use, operation, inspection, and maintenance of a Transuranic Package Transporter Model II (TRUPACT-II), a HalfPACT shipping package, and directly related components. This document complies with the minimum requirements as specified in the TRUPACT-II Safety Analysis Report for Packaging (SARP), HalfPACT SARP, and U.S. Nuclear Regulatory Commission (NRC) Certificates of Compliance (C of C) 9218 and 9279, respectively. In the event of a conflict between this document and the SARP or C of C, the C of C shall govern. The C of Cs state: "each package must be prepared for shipment and operated in accordance with the procedures described in Chapter 7.0, Operating Procedures, of the application." They further state: "each package must be tested and maintained in accordance with the procedures described in Chapter 8.0, Acceptance Tests and Maintenance Program of the Application." Chapter 9.0 of the SARP charges the U.S. Department of Energy (DOE) or the Waste Isolation Pilot Plant (WIPP) management and operating (M&O) contractor with assuring packaging is used in accordance with the requirements of the C of C. Because the packaging is NRC-approved, users need to be familiar with Title 10 Code of Federal Regulations (CFR) §71.8. Any time a user suspects or has indications that the conditions of approval in the C of C were not met, the Carlsbad Field Office (CBFO) shall be notified immediately. The CBFO will evaluate the issue and notify the NRC if required.In accordance with 10 CFR Part 71, certificate holders, packaging users, and contractors or subcontractors who use, design, fabricate, test, maintain, or modify the packaging shall post copies of (1) 10 CFR Part 21 regulations, (2) Section 206 of the Energy Reorganization Act of 1974, and (3) NRC Form 3, Notice to Employees. These documents must be posted in a conspicuous location where the activities subject to these regulations are

  15. Hidden Semi Markov Models for Multiple Observation Sequences: The mhsmm Package for R

    DEFF Research Database (Denmark)

    O'Connell, Jarad Michael; Højsgaard, Søren

    2011-01-01

    models only allow a geometrically distributed sojourn time in a given state, while hidden semi-Markov models extend this by allowing an arbitrary sojourn distribution. We demonstrate the software with simulation examples and an application involving the modelling of the ovarian cycle of dairy cows...

  16. Documentation of 'Care-Packages' for Children in OECD's 2003 Tax/Ben Model, December 2006

    DEFF Research Database (Denmark)

    Hansen, Hans

    This working paper contains documentation for the modelling of schemes implemented in OECD's 2003 Tax/Ben model for use in the 'Carearchitecture' project. The documentation also includes schemes already in the model and used in the calculations for the project. The documented schemes include pers...

  17. mizer: an R package for multispecies, trait-based and community size spectrum ecological modelling

    DEFF Research Database (Denmark)

    Scott, Finlay; Blanchard, Julia L.; Andersen, Ken Haste

    2014-01-01

    1. Size spectrum ecological models are representations of a community of individuals which grow and change trophic level. A key emergent feature of these models is the size spectrum; the total abundance of all individuals that scales negatively with size. The models we focus on are designed...

  18. A Model for Designing Adaptive Laboratory Evolution Experiments.

    Science.gov (United States)

    LaCroix, Ryan A; Palsson, Bernhard O; Feist, Adam M

    2017-04-15

    The occurrence of mutations is a cornerstone of the evolutionary theory of adaptation, capitalizing on the rare chance that a mutation confers a fitness benefit. Natural selection is increasingly being leveraged in laboratory settings for industrial and basic science applications. Despite increasing deployment, there are no standardized procedures available for designing and performing adaptive laboratory evolution (ALE) experiments. Thus, there is a need to optimize the experimental design, specifically for determining when to consider an experiment complete and for balancing outcomes with available resources (i.e., laboratory supplies, personnel, and time). To design and to better understand ALE experiments, a simulator, ALEsim, was developed, validated, and applied to the optimization of ALE experiments. The effects of various passage sizes were experimentally determined and subsequently evaluated with ALEsim, to explain differences in experimental outcomes. Furthermore, a beneficial mutation rate of 10(-6.9) to 10(-8.4) mutations per cell division was derived. A retrospective analysis of ALE experiments revealed that passage sizes typically employed in serial passage batch culture ALE experiments led to inefficient production and fixation of beneficial mutations. ALEsim and the results described here will aid in the design of ALE experiments to fit the exact needs of a project while taking into account the resources required and will lower the barriers to entry for this experimental technique.IMPORTANCE ALE is a widely used scientific technique to increase scientific understanding, as well as to create industrially relevant organisms. The manner in which ALE experiments are conducted is highly manual and uniform, with little optimization for efficiency. Such inefficiencies result in suboptimal experiments that can take multiple months to complete. With the availability of automation and computer simulations, we can now perform these experiments in an optimized

  19. Development of New, Low-Head Hydropower Turbine - Modeling & Laboratory Test DE-EE0005426

    Energy Technology Data Exchange (ETDEWEB)

    Krouse, Wayne [Hydro Green Energy, Westmont, IL (United States)

    2014-12-05

    Hydro Green Energy, LLC (HGE) will complete the design, fabrication and laboratory testing of a scaled, vertically stackable, low-head hydropower turbine called the Modular Bulb Turbine (MBT). HGE will also complete a summary report that includes the laboratory testing results and analysis of the tests. Project Goals: Design, model and test modular bulb turbine for installation in numerous HGE low-head hydropower projects at non-powered USACE dams. Project Results: The sub-scale prototype was tested successfully at a leading US hydraulic laboratory. Laboratory data results agreed well with predicted results from numerical modeling.

  20. Underground Test Area Subproject Phase I Data Analysis Task. Volume VII - Tritium Transport Model Documentation Package

    Energy Technology Data Exchange (ETDEWEB)

    None

    1996-12-01

    Volume VII of the documentation for the Phase I Data Analysis Task performed in support of the current Regional Flow Model, Transport Model, and Risk Assessment for the Nevada Test Site Underground Test Area Subproject contains the tritium transport model documentation. Because of the size and complexity of the model area, a considerable quantity of data was collected and analyzed in support of the modeling efforts. The data analysis task was consequently broken into eight subtasks, and descriptions of each subtask's activities are contained in one of the eight volumes that comprise the Phase I Data Analysis Documentation.

  1. Underground Test Area Subproject Phase I Data Analysis Task. Volume VI - Groundwater Flow Model Documentation Package

    Energy Technology Data Exchange (ETDEWEB)

    None

    1996-11-01

    Volume VI of the documentation for the Phase I Data Analysis Task performed in support of the current Regional Flow Model, Transport Model, and Risk Assessment for the Nevada Test Site Underground Test Area Subproject contains the groundwater flow model data. Because of the size and complexity of the model area, a considerable quantity of data was collected and analyzed in support of the modeling efforts. The data analysis task was consequently broken into eight subtasks, and descriptions of each subtask's activities are contained in one of the eight volumes that comprise the Phase I Data Analysis Documentation.

  2. Interstellar dust modelling: Interfacing laboratory, theoretical and observational studies (The THEMIS model)

    CERN Document Server

    Jones, Ant

    2015-01-01

    The construction of viable and physically-realistic interstellar dust models is only possible if the constraints imposed by laboratory data on interstellar dust analogue materials are respected and used within a meaningful theoretical framework. These physical dust models can then be directly compared to observations without the need for any tuning to fit the observations. Such models will generally fail to achieve the excellent fits to observations that empirical models are able to achieve. However, the physically-realistic approach will necessarily lead to a deeper insight and a fuller understanding of the nature and evolution of interstellar dust. The THEMIS modelling approach, based on (hydrogenated) amorphous carbons and amorphous silicates with metallic Fe and/or FeS nano-inclusions appears to be a promising move in this direction.

  3. Automating calibration, sensitivity and uncertainty analysis of complex models using the R package Flexible Modeling Environment (FME): SWAT as an example

    Science.gov (United States)

    Wu, Y.; Liu, S.

    2012-01-01

    Parameter optimization and uncertainty issues are a great challenge for the application of large environmental models like the Soil and Water Assessment Tool (SWAT), which is a physically-based hydrological model for simulating water and nutrient cycles at the watershed scale. In this study, we present a comprehensive modeling environment for SWAT, including automated calibration, and sensitivity and uncertainty analysis capabilities through integration with the R package Flexible Modeling Environment (FME). To address challenges (e.g., calling the model in R and transferring variables between Fortran and R) in developing such a two-language coupling framework, 1) we converted the Fortran-based SWAT model to an R function (R-SWAT) using the RFortran platform, and alternatively 2) we compiled SWAT as a Dynamic Link Library (DLL). We then wrapped SWAT (via R-SWAT) with FME to perform complex applications including parameter identifiability, inverse modeling, and sensitivity and uncertainty analysis in the R environment. The final R-SWAT-FME framework has the following key functionalities: automatic initialization of R, running Fortran-based SWAT and R commands in parallel, transferring parameters and model output between SWAT and R, and inverse modeling with visualization. To examine this framework and demonstrate how it works, a case study simulating streamflow in the Cedar River Basin in Iowa in the United Sates was used, and we compared it with the built-in auto-calibration tool of SWAT in parameter optimization. Results indicate that both methods performed well and similarly in searching a set of optimal parameters. Nonetheless, the R-SWAT-FME is more attractive due to its instant visualization, and potential to take advantage of other R packages (e.g., inverse modeling and statistical graphics). The methods presented in the paper are readily adaptable to other model applications that require capability for automated calibration, and sensitivity and uncertainty

  4. Remaining Sites Verification Package for the 141-C Large Animal Barn and Biology Laboratory (Hog Barn), Waste Site Reclassification Form 2006-027

    Energy Technology Data Exchange (ETDEWEB)

    R. A. Carlson

    2006-05-24

    The 141-C waste site is a former large animal barn and biology laboratory within the 100-F Area experimental animal farm. Strontium-90, arsenic, and multiple polycyclic aromatic hydrocarbons were detected within residual demolition debris at concentrations exceeding cleanup criteria. The site has been remediated by removing approximately 900 bank cubic meters of soil and debris within the former building footprint to the Environmental Restoration Disposal Facility. The results of verification sampling demonstrated that residual contaminant concentrations do not preclude any future uses and allow for unrestricted use of shallow zone soils. The results also showed that residual contaminant concentrations are protective of groundwater and the Columbia River.

  5. Modeling & Simulation Education for the Acquisition and T&E Workforce: FY07 Deliverable Package

    Science.gov (United States)

    2007-12-01

    Malamed . 1998. Modern Simulation and Modeling, John Wiley and Sons, Canada. NPS-SE--08-M01 113 Zeigler, Bernard P., Tag Gon Kim, Herbert Praehofer...Reuven Y., Bemjamin Malamed . 1998. Modern Simulation and Modeling, John Wiley and Sons, Canada. NPS-SE--08-M01 116 Competency Level...and output analysis o simulation measures of effectiveness • Rubinstein, Reuven Y., Bemjamin Malamed . 1998. Modern Simulation and Modeling

  6. Report on first simulation model, that predicts the feasibility of communicative packaging concepts : Deliverable 6.14

    NARCIS (Netherlands)

    Canters, R.A.M.; Wienk, I.M.; Kreft-Pereira Da Silva, F.I.D.G.; Tromp, S.O.

    2005-01-01

    One of the objectives of this part of the SustainPack project (WP 6.3) is to facilitate the implementation process of communicative packaging in the chain of production, storage, distribution and use of packed products. New packaging concepts are more easily implemented if the benefits can be demons

  7. In-Package Chemistry Abstraction

    Energy Technology Data Exchange (ETDEWEB)

    E. Thomas

    2004-11-09

    This report was developed in accordance with the requirements in ''Technical Work Plan for: Regulatory Integration Modeling and Analysis of the Waste Form and Waste Package'' (BSC 2004 [DIRS 171583]). The purpose of the in-package chemistry model is to predict the bulk chemistry inside of a breached waste package and to provide simplified expressions of that chemistry as function of time after breach to Total Systems Performance Assessment for the License Application (TSPA-LA). The scope of this report is to describe the development and validation of the in-package chemistry model. The in-package model is a combination of two models, a batch reactor model that uses the EQ3/6 geochemistry-modeling tool, and a surface complexation model that is applied to the results of the batch reactor model. The batch reactor model considers chemical interactions of water with the waste package materials and the waste form for commercial spent nuclear fuel (CSNF) waste packages and codisposed waste packages that contain both high-level waste glass (HLWG) and DOE spent fuel. The surface complexation model includes the impact of fluid-surface interactions (i.e., surface complexation) on the resulting fluid composition. The model examines two types of water influx: (1) the condensation of water vapor that diffuses into the waste package, and (2) seepage water that enters the waste package from the drift as a liquid. (1) Vapor Influx Case: The condensation of vapor onto the waste package internals is simulated as pure H2O and enters at a rate determined by the water vapor pressure for representative temperature and relative humidity conditions. (2) Water Influx Case: The water entering a waste package from the drift is simulated as typical groundwater and enters at a rate determined by the amount of seepage available to flow through openings in a breached waste package. TSPA-LA uses the vapor influx case for the nominal scenario for simulations where the waste

  8. Application of Thermal Network Model to Transient Thermal Analysis of Power Electronic Package Substrate

    National Research Council Canada - National Science Library

    Ishizuka, Masaru; Hatakeyama, Tomoyuki; Funawatashi, Yuichi; Koizumi, katsuhiro

    2011-01-01

    .... This paper describes an application of the thermal network method to the transient thermal analysis of multichip modules and proposes a simple model for the thermal analysis of multichip modules as a preliminary thermal design tool. On the basis of the result of transient thermal analysis, the validity of the thermal network method and the simple thermal analysis model is confirmed.

  9. Variability in the Effectiveness of a Video Modeling Intervention Package for Children with Autism

    Science.gov (United States)

    Plavnick, Joshua B.; MacFarland, Mari C.; Ferreri, Summer J.

    2015-01-01

    Video modeling is an evidence-based instructional strategy for teaching a variety of skills to individuals with autism. Despite the effectiveness of this strategy, there is some uncertainty regarding the conditions under which video modeling is likely to be effective. The present investigation examined the differential effectiveness of video…

  10. Electromagnetic modeling and optimization of packaged photodetector modules for 100 Gbit/s applications

    DEFF Research Database (Denmark)

    Jiang, Chenhui; Krozer, Viktor; Bach, H-G;

    2008-01-01

    In this paper, we propose an accurate full 3D EM behavioral model of PD chips for the first time. The model, which is meshed at 130 GHz, runs for about 17 minutes on an Intel Core2 Duo CPU@3 GHz PC with 3.5 GB of RAM. The impact of various parameters in wire- bonding transitions for transmission...

  11. Development of animal model for Chandipura virus in laboratory mice

    Institute of Scientific and Technical Information of China (English)

    Raut; CG; Jadi; RS; Chinchwale; AS; Daware; MM

    2005-01-01

    In recent years there was a outbreak of Chandipura virus(CHPV)in Sothern part of India causing encephalitis and acutedeathin children of age group of2.5months to15years withthe mortality rate of55.6%.As this disease is of acutedeath nature in humans no data available on pathogenesis.To understandthe pathogenesis of the disease caused by CHPV,experimental infection in laboratory swiss albino micewas conducted.Animals of age upto one weekfound highlysusceptible to all the routes of inoculation.For further stu...

  12. Strategic mobility modeling at Oak Ridge National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, R.G.; Yow, T.G.

    1990-01-01

    The Oak Ridge National Laboratory (ORNL) has been involved in strategic mobility planning and analysis for the Department of Defense (DOD) for approximately six years. This work is conducted under four interagency agreements between DOD and the Department of Energy (DOE): Air Force/MAC -- Airlift Deployment Analysis System (ADANS), Army/MTMC -- Strategic Deployment System (STRADS) and Integrated Booking System (IBS), Navy/MSC -- Scheduling Algorithm for Improving Lift (SAIL), and USTRANSCOM -- Deployment Analysis Prototype (DAP) and Flow and Analysis System for TRANSCOM (FAST).

  13. The ASTROID Simulator Software Package: Realistic Modelling of High-Precision High-Cadence Space-Based Imaging

    CERN Document Server

    Marcos-Arenal, P; De Ridder, J; Huygen, R; Aerts, C

    2014-01-01

    The preparation of a space-mission that carries out any kind of imaging to detect high-precision low-amplitude variability of its targets requires a robust model for the expected performance of its instruments. This model cannot be derived from simple addition of noise properties due to the complex interaction between the various noise sources. While it is not feasible to build and test a prototype of the imaging device on-ground, realistic numerical simulations in the form of an end-to-end simulator can be used to model the noise propagation in the observations. These simulations not only allow studying the performance of the instrument, its noise source response and its data quality, but also the instrument design verification for different types of configurations, the observing strategy and the scientific feasibility of an observing proposal. In this way, a complete description and assessment of the objectives to expect from the mission can be derived. We present a high-precision simulation software packag...

  14. ATLAS software packaging

    CERN Document Server

    Rybkin, G

    2012-01-01

    Software packaging is indispensable part of build and prerequisite for deployment processes. Full ATLAS software stack consists of TDAQ, HLT, and Offline software. These software groups depend on some 80 external software packages. We present tools, package PackDist, developed and used to package all this software except for TDAQ project. PackDist is based on and driven by CMT, ATLAS software configuration and build tool, and consists of shell and Python scripts. The packaging unit used is CMT project. Each CMT project is packaged as several packages - platform dependent (one per platform available), source code excluding header files, other platform independent files, documentation, and debug information packages (the last two being built optionally). Packaging can be done recursively to package all the dependencies. The whole set of packages for one software release, distribution kit, also includes configuration packages and contains some 120 packages for one platform. Also packaged are physics analysis pro...

  15. Package Equivalent Reactor Networks as Reduced Order Models for Use with CAPE-OPEN Compliant Simulation

    Energy Technology Data Exchange (ETDEWEB)

    Meeks, E.; Chou, C. -P.; Garratt, T.

    2013-03-31

    Engineering simulations of coal gasifiers are typically performed using computational fluid dynamics (CFD) software, where a 3-D representation of the gasifier equipment is used to model the fluid flow in the gasifier and source terms from the coal gasification process are captured using discrete-phase model source terms. Simulations using this approach can be very time consuming, making it difficult to imbed such models into overall system simulations for plant design and optimization. For such system-level designs, process flowsheet software is typically used, such as Aspen Plus® [1], where each component where each component is modeled using a reduced-order model. For advanced power-generation systems, such as integrated gasifier/gas-turbine combined-cycle systems (IGCC), the critical components determining overall process efficiency and emissions are usually the gasifier and combustor. Providing more accurate and more computationally efficient reduced-order models for these components, then, enables much more effective plant-level design optimization and design for control. Based on the CHEMKIN-PRO and ENERGICO software, we have developed an automated methodology for generating an advanced form of reduced-order model for gasifiers and combustors. The reducedorder model offers representation of key unit operations in flowsheet simulations, while allowing simulation that is fast enough to be used in iterative flowsheet calculations. Using high-fidelity fluiddynamics models as input, Reaction Design’s ENERGICO® [2] software can automatically extract equivalent reactor networks (ERNs) from a CFD solution. For the advanced reduced-order concept, we introduce into the ERN a much more detailed kinetics model than can be included practically in the CFD simulation. The state-of-the-art chemistry solver technology within CHEMKIN-PRO allows that to be accomplished while still maintaining a very fast model turn-around time. In this way, the ERN becomes the basis for

  16. Remaining Sites Verification Package for the 331 Life Sciences Laboratory Drain Field Septic System, Waste Site Reclassification Form 2008-020

    Energy Technology Data Exchange (ETDEWEB)

    J. M. Capron

    2008-10-16

    The 331 Life Sciences Laboratory Drain Field (LSLDF) septic system waste site consists of a diversion chamber, two septic tanks, a distribution box, and a drain field. This septic system was designed to receive sanitary waste water, from animal studies conducted in the 331-A and 331-B Buildings, for discharge into the soil column. However, field observations and testing suggest the 331 LSLDF septic system did not receive any discharges. In accordance with this evaluation, the confirmatory sampling results support a reclassification of the 331 LSLDF waste site to No Action. This site does not have a deep zone or other condition that would warrant an institutional control in accordance with the 300-FF-2 ROD under the industrial land use scenario.

  17. The impact of packaging on product competition

    Directory of Open Access Journals (Sweden)

    Maryam Masoumi

    2012-09-01

    Full Text Available The primary objective of this paper is to detect important factors, which are influencing competitive advantage. The proposed model of this paper uses sampling technique to measure characteristics of society. There are eight independent variables for the proposed study of this paper including packaging endurance, easy distribution, customer promotion through packaging, packaging structure, packaging as silent advertiser, diversity of packaging, clean and healthy packaging and innovation in packaging. The proposed study uses structural equation modeling to either accept or reject all hypotheses associated with the proposed study of this paper. The population of this study includes all managers and experts who are involved in packaging products. We used simple sampling technique and chooses 300 from a population of 450 people who are considered as the population of this survey. Cronbach alpha was determined as 0.732, which is above the minimum acceptable level. The results confirm that all mentioned factors influence competitiveness, effectively.

  18. Improvement in Space Food Packaging Methods Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Space Food Systems Laboratory's (SFSL) current Bulk Overwrap Bag (BOB) package, while simple and effective, leaves room for improvement. Currently, BOBs are...

  19. Mars Science Laboratory; A Model for Event-Based EPO

    Science.gov (United States)

    Mayo, Louis; Lewis, E.; Cline, T.; Stephenson, B.; Erickson, K.; Ng, C.

    2012-10-01

    The NASA Mars Science Laboratory (MSL) and its Curiosity Rover, a part of NASA's Mars Exploration Program, represent the most ambitious undertaking to date to explore the red planet. MSL/Curiosity was designed primarily to determine whether Mars ever had an environment capable of supporting microbial life. NASA's MSL education program was designed to take advantage of existing, highly successful event based education programs to communicate Mars science and education themes to worldwide audiences through live webcasts, video interviews with scientists, TV broadcasts, professional development for teachers, and the latest social media frameworks. We report here on the success of the MSL education program and discuss how this methodological framework can be used to enhance other event based education programs.

  20. Precessional states in a laboratory model of the Earth's core

    Science.gov (United States)

    Triana, S. A.; Zimmerman, D. S.; Lathrop, D. P.

    2012-04-01

    A water-filled three-meter diameter spherical shell, geometrically similar to the Earth's core, shows precessionally forced flows. The precessional torque is supplied by the daily rotation of the laboratory by the Earth. We identify the precessionally forced flow to be primarily the spin-over inertial mode, i.e., a uniform vorticity flow whose rotation axis is not aligned with the sphere's rotation axis. A systematic study of the spin-over mode is carried out, showing that the amplitude depends on the ratio of precession to rotation rates (the Poincaré number), in marginal qualitative agreement with Busse's (1968) laminar theory. We find its phase differs significantly though, likely due to topographic effects. At high rotation rates, free shear layers are observed. Comparison with previous computational studies and implications for the Earth's core are discussed.

  1. Developing a Laboratory Model for the Professional Preparation of Future Science Teachers: A Situated Cognition Perspective

    Science.gov (United States)

    Sweeney, Aldrin E.; Paradis, Jeffrey A.

    2004-04-01

    Although laboratory activities are widely acknowledged as being fundamental to the teaching of science, many secondary science school teachers have limited knowledge of how to design and run effective teaching laboratories. Utilising a situated cognition theoretical framework, we discuss our collaborative efforts to develop a laboratory based model for the professional preparation of secondary level science teachers. Findings from the study suggest that the learning which occurs in the laboratory context may be transferred (with appropriate modifications) to the secondary science classroom. Implications also are presented for science teacher preparation, ongoing professional development, and further study.

  2. Model-Based Reasoning in the Physics Laboratory: Framework and Initial Results

    Science.gov (United States)

    Zwickl, Benjamin M.; Hu, Dehui; Finkelstein, Noah; Lewandowski, H. J.

    2015-01-01

    We review and extend existing frameworks on modeling to develop a new framework that describes model-based reasoning in introductory and upper-division physics laboratories. Constructing and using models are core scientific practices that have gained significant attention within K-12 and higher education. Although modeling is a broadly applicable…

  3. RPC Stereo Processor (rsp) - a Software Package for Digital Surface Model and Orthophoto Generation from Satellite Stereo Imagery

    Science.gov (United States)

    Qin, R.

    2016-06-01

    Large-scale Digital Surface Models (DSM) are very useful for many geoscience and urban applications. Recently developed dense image matching methods have popularized the use of image-based very high resolution DSM. Many commercial/public tools that implement matching methods are available for perspective images, but there are rare handy tools for satellite stereo images. In this paper, a software package, RPC (rational polynomial coefficient) stereo processor (RSP), is introduced for this purpose. RSP implements a full pipeline of DSM and orthophoto generation based on RPC modelled satellite imagery (level 1+), including level 2 rectification, geo-referencing, point cloud generation, pan-sharpen, DSM resampling and ortho-rectification. A modified hierarchical semi-global matching method is used as the current matching strategy. Due to its high memory efficiency and optimized implementation, RSP can be used in normal PC to produce large format DSM and orthophotos. This tool was developed for internal use, and may be acquired by researchers for academic and non-commercial purpose to promote the 3D remote sensing applications.

  4. Modeling and Testing of EVs - Preliminary Study and Laboratory Development

    DEFF Research Database (Denmark)

    Yang, Guang-Ya; Marra, Francesco; Nielsen, Arne Hejde

    2010-01-01

    impact at different geographical areas, as well as driving and charging patterns. Electric circuit model is deployed in this work to represent the electrical properties of a lithium-ion battery. This paper reports the preliminary modeling and validation work based on manufacturer data sheet and realistic......Electric vehicles (EVs) are expected to play a key role in the future energy management system to stabilize both supply and consumption with the presence of high penetration of renewable generation. A reasonably accurate model of battery is a key element for the study of EVs behavior and the grid...... tests, followed by the suggestions towards a feasible battery model for further studies....

  5. Modeling and Testing of EVs - Preliminary Study and Laboratory Development

    DEFF Research Database (Denmark)

    Yang, Guang-Ya; Marra, Francesco; Nielsen, Arne Hejde;

    2010-01-01

    Electric vehicles (EVs) are expected to play a key role in the future energy management system to stabilize both supply and consumption with the presence of high penetration of renewable generation. A reasonably accurate model of battery is a key element for the study of EVs behavior and the grid...... tests, followed by the suggestions towards a feasible battery model for further studies....

  6. The performance effect of the Lean package – a survey study using a structural equation model

    DEFF Research Database (Denmark)

    Kristensen, Thomas Borup; Israelsen, Poul

    practices. Furthermore, the paper provides evidence that supports the view that actions of middle management enhance performance in the system-wide approach to Lean. Originality/value - In contrast to previous surveys, our results support case studies describing the multiple interdependencies of Lean......Purpose - Our aim is to test and validate a system-wide approach using mediating relationships in a structural equation model in order to understand how the practices of Lean affect performance. Design/methodology/approach – A cross-sectional survey with 200 responding companies indicating...... that they use Lean. This is analyzed in a structural quation model setting. Findings - Previous quantitative research has shown mixed results for the performance of Lean because they have not addressed the system-wide mediating relations between Lean practices. We find that Companies using a system...

  7. Tracked Vehicle Dynamics Modeling and Simulation Methodology, with Control, using RecurDyn Software Package

    Science.gov (United States)

    2011-09-01

    track segment, with pins connecting each track segment. The modeler must align each segment properly with the track pins with the sprocket teeth and...representative track segment is copied and linked together using a simplified algorithm which assumes each track segment is identical, with force/ torque pairs...simulation, RecurDyn feeds CoLink the desired inputs (error term, speed, direction, etc), CoLink performs the programmed operation (generates torque

  8. Admission Laboratory Results to Enhance Prediction Models of Postdischarge Outcomes in Cardiac Care.

    Science.gov (United States)

    Pine, Michael; Fry, Donald E; Hannan, Edward L; Naessens, James M; Whitman, Kay; Reband, Agnes; Qian, Feng; Schindler, Joseph; Sonneborn, Mark; Roland, Jaclyn; Hyde, Linda; Dennison, Barbara A

    Predictive modeling for postdischarge outcomes of inpatient care has been suboptimal. This study evaluated whether admission numerical laboratory data added to administrative models from New York and Minnesota hospitals would enhance the prediction accuracy for 90-day postdischarge deaths without readmission (PD-90) and 90-day readmissions (RA-90) following inpatient care for cardiac patients. Risk-adjustment models for the prediction of PD-90 and RA-90 were designed for acute myocardial infarction, percutaneous cardiac intervention, coronary artery bypass grafting, and congestive heart failure. Models were derived from hospital claims data and were then enhanced with admission laboratory predictive results. Case-level discrimination, goodness of fit, and calibration were used to compare administrative models (ADM) and laboratory predictive models (LAB). LAB models for the prediction of PD-90 were modestly enhanced over ADM, but negligible benefit was seen for RA-90. A consistent predictor of PD-90 and RA-90 was prolonged length of stay outliers from the index hospitalization.

  9. Yucca Mountain Waste Package Closure System

    Energy Technology Data Exchange (ETDEWEB)

    shelton-davis; Colleen Shelton-Davis; Greg Housley

    2005-10-01

    The current disposal path for high-level waste is to place the material into secure waste packages that are inserted into a repository. The Idaho National Laboratory has been tasked with the development, design, and demonstration of the waste package closure system for the repository project. The closure system design includes welding three lids and a purge port cap, four methods of nondestructive examination, and evacuation and backfill of the waste package, all performed in a remote environment. A demonstration of the closure system will be performed with a full-scale waste package.

  10. Yucca Mountain Waste Package Closure System

    Energy Technology Data Exchange (ETDEWEB)

    Herschel Smartt; Arthur Watkins; David Pace; Rodney Bitsoi; Eric Larsen; Timothy McJunkin; Charles Tolle

    2006-04-01

    The current disposal path for high-level waste is to place the material into secure waste packages that are inserted into a repository. The Idaho National Laboratory has been tasked with the development, design, and demonstration of the waste package closure system for the repository project. The closure system design includes welding three lids and a purge port cap, four methods of nondestructive examination, and evacuation and backfill of the waste package, all performed in a remote environment. A demonstration of the closure system will be performed with a full-scale waste package.

  11. Models for Estimating Research and Development Manpower in Navy Laboratories

    Science.gov (United States)

    1988-10-01

    Mathematics Policy Research, Inc. under subcontract to Mathtech, Inc. of Falls Church, Virginia, under contract N00123-83- D-0520. The contracting officer’s...primary objective of forecasting staffing requirements for the SPAWAR R&D Centers. Besides changing policy variables and projecting the effects on...known values. For NOSC, NSWC, DTNSRDC, NUSC, and NCSC, the models were used to backcast FY83. For NADC, the model was used to backcast FY84. For

  12. Training a Data Scientist: A Multi-year, Multi-Project View from the Trenches of the Regional Climate Model Evaluation System at the Jet Propulsion Laboratory

    Science.gov (United States)

    Whittell, J.

    2013-12-01

    Society and technology growth has lead to an age of voluminous, heterogeneous data that requires timely analysis. There are many instruments, models and experiments that generate large amounts of data in various formats, resolutions and location. The answers to the questions posed are embedded in these big data that require the formidable task of data handling, manipulation, visualization and storage. To navigate this space persons with experience handling these data and also with some (high-level or deeper) knowledge of the science that these data represent are necessary. Persons with this unique set of skills are data scientists. Most data scientists possess a cross-disciplinary approach to their research/work, but few actually possess a true inter-disciplinary background and expertise that is demanded of the profession. This poster outlines a method in which a young person was introduced to data science from an inter-disciplinary perspective within the STEM disciplines. The Regional Climate Model Evaluation System (RCMES, http://rcmes.jpl.nasa.gov) at NASA's Jet Propulsion Laboratory seeks to improve regional climate model evaluation by comparing past model predictions with observation datasets including those originating from Earth-orbiting satellite data. The successful development of the RCMES software package relies on collaboration between climate scientists and computer scientists, as evidenced by the RCMES team's longstanding work with the International Coordinated Regional Downscaling Experiment (CORDEX), a large, multidisciplinary modeling group focused on regional downscaling. Over a total of 17 weeks during the summers of 2011, 2012, and 2013, a high school student, with no formal background in either the earth sciences or computer technology, was immersed (interned) with the RCMES team. This student successfully provided support on both disciplines of the project and developed their 'data scientist toolkit' through learning about the science involved

  13. THE LOS ALAMOS NATIONAL LABORATORY ATMOSPHERIC TRANSPORT AND DIFFUSION MODELS

    Energy Technology Data Exchange (ETDEWEB)

    M. WILLIAMS [and others

    1999-08-01

    The LANL atmospheric transport and diffusion models are composed of two state-of-the-art computer codes. The first is an atmospheric wind model called HOThlAC, Higher Order Turbulence Model for Atmospheric circulations. HOTMAC generates wind and turbulence fields by solving a set of atmospheric dynamic equations. The second is an atmospheric diffusion model called RAPTAD, Random Particle Transport And Diffusion. RAPTAD uses the wind and turbulence output from HOTMAC to compute particle trajectories and concentration at any location downwind from a source. Both of these models, originally developed as research codes on supercomputers, have been modified to run on microcomputers. Because the capability of microcomputers is advancing so rapidly, the expectation is that they will eventually become as good as today's supercomputers. Now both models are run on desktop or deskside computers, such as an IBM PC/AT with an Opus Pm 350-32 bit coprocessor board and a SUN workstation. Codes have also been modified so that high level graphics, NCAR Graphics, of the output from both models are displayed on the desktop computer monitors and plotted on a laser printer. Two programs, HOTPLT and RAPLOT, produce wind vector plots of the output from HOTMAC and particle trajectory plots of the output from RAPTAD, respectively. A third CONPLT provides concentration contour plots. Section II describes step-by-step operational procedures, specifically for a SUN-4 desk side computer, on how to run main programs HOTMAC and RAPTAD, and graphics programs to display the results. Governing equations, boundary conditions and initial values of HOTMAC and RAPTAD are discussed in Section III. Finite-difference representations of the governing equations, numerical solution procedures, and a grid system are given in Section IV.

  14. A cost and technical efficiency analysis of two alternative models for implementing the basic package of health services in Afghanistan.

    Science.gov (United States)

    Blaakman, Aaron Philip; Salehi, Ahmad Shah; Boitard, Romain

    2014-01-01

    Since 2003, the Afghan Ministry of Public Health (MoPH) and international partners have directed a contracting-out model through which non-governmental organisations (NGOs) deliver the Basic Package of Health Services (BPHS) in 31 of the 34 Afghan provinces. The MoPH also managed health service delivery in three provinces under an alternative initiative entitled Strengthening Mechanisms (SM). In 2011, under the authority of the MoPH and Delegation of the European Union to Afghanistan, EPOS Health Management conducted a cost and technical efficiency study of the contracting-out and SM mechanisms in six provinces to examine economic trade-offs in the provision of the BPHS. The study provides analyses of all resource inputs and primary outputs of the BPHS in the six provinces during 2008 and 2009. The authors examined technical efficiency using Data Envelopment Analysis (DEA) at the BPHS facility level. Cost analysis results indicate that the weighted average cost per BPHS outpatient visit totalled $3.41 in the SM provinces and $5.39 in the NGO-led provinces in 2009. Furthermore, the data envelopment analyses (DEAs) indicate that facilities in the three NGO-led provinces scored 0.168 points higher on the DEA scale (0-1) than SM facilities. The authors conclude that an approximate 60% increase in costs yielded a 16.8% increase in technical efficiency in the delivery of the BPHS during 2009 in the six provinces.

  15. Developing a training package.

    Science.gov (United States)

    Minogue, Virginia; Donskoy, Anne-Laure

    2017-06-12

    Purpose The purpose of this paper is to outline the development of a training package for service users and carers with an interest in NHS health and social care research. It demonstrates how the developers used their unique experience and expertise as service users and carers to inform their work. Design/methodology/approach Service users and carers, NHS Research and Development Forum working group members, supported by health professionals, identified a need for research training that was tailored to other service user and carer needs. After reviewing existing provision and drawing on their training and support experience, they developed a training package. Sessions from the training package were piloted, which evaluated positively. In trying to achieve programme accreditation and training roll-out beyond the pilots, the group encountered several challenges. Findings The training package development group formed good working relationships and a co-production model that proved sustainable. However, challenges were difficult to overcome owing to external factors and financial constraints. Practical implications Lessons learnt by the team are useful for other service users and carer groups working with health service professionals. Training for service users and carers should be designed to meet their needs; quality and consistency are also important. The relationships between service user and carer groups, and professionals are important to understanding joint working. Recognising and addressing challenges at the outset can help develop strategies to overcome challenges and ensure project success. Originality/value The training package was developed by service users and carers for other service users and carers. Their unique health research experience underpinned the group's values and training development.

  16. Taenia solium: current understanding of laboratory animal models of taeniosis.

    Science.gov (United States)

    Flisser, A; Avila, G; Maravilla, P; Mendlovic, F; León-Cabrera, S; Cruz-Rivera, M; Garza, A; Gómez, B; Aguilar, L; Terán, N; Velasco, S; Benítez, M; Jimenez-Gonzalez, D E

    2010-03-01

    Neurocysticercosis is a public health problem in many developing countries and is the most frequent parasitic disease of the brain. The human tapeworm carrier is the main risk factor for acquiring neurocysticercosis. Since the parasite lodges only in the human intestine, experimental models of Taenia solium taeniosis have been explored. Macaques, pigs, dogs, cats and rabbits are unsuccessful hosts even in immunodepressed status. By contrast, rodents are adequate hosts since tapeworms with mature, pregravid and, in some cases, gravid proglottids develop after infection. In this review, information that has been generated with experimental models of taeniosis due to T. solium is discussed. Initially, the use of the model for immunodiagnosis of human taeniosis and evaluation of intervention measures is summarized. Next, descriptions of tapeworms and comparison of hamsters, gerbils and other mammals as experimental models are discussed, as well as data on the humoral immune response, the inflammatory reaction and the production of cytokines associated to Th1 and Th2 responses in the intestinal mucosa. Finally, evaluation of protection induced against the development of tapeworms by recombinant T. solium calreticulin in hamsters is summarized and compared to other studies.

  17. Amphibians as animal models for laboratory research in physiology.

    Science.gov (United States)

    Burggren, Warren W; Warburton, Stephen

    2007-01-01

    The concept of animal models is well honored, and amphibians have played a prominent part in the success of using key species to discover new information about all animals. As animal models, amphibians offer several advantages that include a well-understood basic physiology, a taxonomic diversity well suited to comparative studies, tolerance to temperature and oxygen variation, and a greater similarity to humans than many other currently popular animal models. Amphibians now account for approximately 1/4 to 1/3 of lower vertebrate and invertebrate research, and this proportion is especially true in physiological research, as evident from the high profile of amphibians as animal models in Nobel Prize research. Currently, amphibians play prominent roles in research in the physiology of musculoskeletal, cardiovascular, renal, respiratory, reproductive, and sensory systems. Amphibians are also used extensively in physiological studies aimed at generating new insights in evolutionary biology, especially in the investigation of the evolution of air breathing and terrestriality. Environmental physiology also utilizes amphibians, ranging from studies of cryoprotectants for tissue preservation to physiological reactions to hypergravity and space exploration. Amphibians are also playing a key role in studies of environmental endocrine disruptors that are having disproportionately large effects on amphibian populations and where specific species can serve as sentinel species for environmental pollution. Finally, amphibian genera such as Xenopus, a genus relatively well understood metabolically and physiologically, will continue to contribute increasingly in this new era of systems biology and "X-omics."

  18. Laboratory Models of Thermal Convection in Porous Media

    Science.gov (United States)

    Cooper, C. A.; Breitmeyer, R.; Schumer, R.; Voepel, H.; Decker, D.

    2011-12-01

    Experiments have been conducted to measure the length and times scales of thermal plumes in laboratory porous media. A polycarbonate cell 1 m high x 75 cm wide x 2.54 cm deep filled with 3 mm glass beads is heated uniformly from the bottom using electrical heat tape. The heat tape is in direct contact with an aluminum alloy heat exchanger sandwiched between the two vertical plates, and a digital controller is used to maintain constant temperature. The upper boundary is kept at constant temperature by circulating cold water from a constant-temperature refrigerating bath through copper tubes in contact with the upper part of the cell. Flow is visualized by mixing a neutrally buoyant thermochromic liquid tracer in the working fluid (water and glycerin). TLCs are liquid crystals manufactured to change color as a function of temperature. Color change is repeatable and reversible with a response time to temperature change is less than 0.01 s. Image acquisition is done using a CCD camera, and three images are captured nearly simultaneously, each with a red, blue, or green filter over the camera lens. The three images are then combined to make a true color image. At each pixel in the image, hue is extracted and a calibration curve is developed to relate hue to temperature. In one experiment with a 10 degree C temperature difference between the upper and lower boundaries, the onset of convection began within 26 minutes, which is about half the time predicted by a scale analysis. The initial velocity of all plumes is on the order of 15 cm/hr, although some plumes stop moving before reaching the upper boundary of the cell. There are several reasons for plume deceleration: (1) As plumes travel vertically, they alter the initial temperature profile of the fluid such that the temperature field makes constant adjustments, which affects the dimensions, velocities, and interactions of the plumes; (2) adjacent plumes merge, resulting in a single larger plume; and (3) interactions

  19. Laboratory animals as surrogate models of human obesity

    Institute of Scientific and Technical Information of China (English)

    Cecilia NILSSON; Kirsten RAUN; Fei-fei YAN; Marianne O LARSEN; Mads TANG-CHRISTENSEN

    2012-01-01

    Obesity and obesity-related metabolic diseases represent a growing socioeconomic problem throughout the world.Great emphasis has been put on establishing treatments for this condition,including pharmacological intervention.However,there are many obstacles and pitfalls in the development process from pre-clinical research to the pharmacy counter,and there is no certainty that what has been observed pre-clinically will translate into an improvement in human health.Hence,it is important to test potential new drugs in a valid translational model early in their development.In the current mini-review,a number of monogenetic and polygenic models of obesity will be discussed in view of their translational character.

  20. Development of a laboratory animal model for infectious bovine keratoconjunctivitis.

    Science.gov (United States)

    Chandler, R L; Turfrey, B A; Smith, K

    1982-01-01

    Guinea pigs, gerbils, voles, golden hamsters and Chinese hamsters exposed to experimental infection with Moraxella bovis by ocular instillation or associated routes showed transient infections only and no clinical signs. Five strains of mice were of similarly low susceptibility but another, the C57 Bl strain, was relatively susceptible and treatment with corticosteroid before infection regularly produced keratoconjunctivitis. This system therefore offers a promising model for studies on infectious bovine keratoconjunctivitis.

  1. Simulations of Embedded Electromagnetic Particle Velocity Gauge Package Response in Gas-Gun Experiments

    Science.gov (United States)

    Finn, K. L.; James, H. R.; Whitworth, N. J.; Handley, C. A.

    2009-12-01

    In recent years a comprehensive suite of gas-gun particle velocity gauge experiments have been conducted at Los Alamos National Laboratory. Detailed analysis of this data has led to advances in the understanding of the shock to detonation transition in polymer bonded explosives hydrocode simulations of the experiments are frequently used to calibrate reactive-burn models. In these simulations the gauges are modelled using Lagrangian markers with no physical representation of the gauge package. In contrast the experimental gauge package consists of etched aluminium sandwiched between two sheets of FEP Teflon using an urethane-based glue. The gauge package is approximately 60 μm thick is positioned between two wedge-shaped pieces of explosive at an angle of 30 degrees to form a right circular cylinder. This paper investigates with one-dimensional calculations whether there is a need to include an accurate representation of the gauge package within future hydrocode simulations.

  2. DEVELOPMENT OF THE HS99 AIR TRANSPORT TYPE A FISSILE PACKAGE

    Energy Technology Data Exchange (ETDEWEB)

    Blanton, P.; Eberl, K.

    2012-07-10

    An air-transport Type A Fissile radioactive shipping package for the transport of special form uranium sources has been developed by the Savannah River National Laboratory (SRNL) for the Department of Homeland Security. The Package model number is HS99 for Homeland Security Model 99. This paper presents the major design features of the HS99 and highlights engineered materials necessary for meeting the design requirements for this light-weight Type AF packaging. A discussion is provided demonstrating how the HS99 complies with the regulatory safety requirements of the Nuclear Regulatory Commission. The paper summarizes the results of structural testing to specified in 10 CFR 71 for Normal Conditions of Transport and Hypothetical Accident Conditions events. Planned and proposed future missions for this packaging are also addressed.

  3. Elastic laboratory measurements and modeling of saturated basalts

    Science.gov (United States)

    Adam, Ludmila; Otheim, Thomas

    2013-03-01

    Understanding the elastic behavior of basalt is important to seismically monitor volcanoes, subsea basalts, and carbon sequestration in basalt. We estimate the elastic properties of basalt samples from the Snake River Plain, Idaho, at ultrasonic (0.8 MHz) and seismic (2-300 Hz) frequencies. To test the sensitivity of seismic waves to the fluid content in the pore structure, measurements are performed at three saturation conditions: saturated with liquid CO2, water, and dry. When CO2 replaces water, the P-wave velocity drops, on average, by 10%. Vesicles and cracks, observed in the rock microstructure, control the relaxation of pore-fluid pressures in the rock as a wave propagates. The bulk and shear moduli of basalts saturated with liquid CO2 are not frequency dependent, suggesting that fluid pore pressures are in equilibrium between 2 Hz and 0.8 MHz. However, when samples are water saturated, the bulk modulus of the rock is frequency dependent. Modeling with Gassmann's equations predicts the measured saturated rock bulk modulus for all fluids for frequencies below 20 Hz but underpredicts the water-saturated basalt bulk modulus for frequencies greater than 20 Hz. The most likely reason is that the pore-fluid pressures are unrelaxed. Instead, the ultrasonic frequency rock moduli are modeled with high-frequency elastic theories of squirt flow and Kuster-Toksöz (KT). Although KT's model is based on idealized pore shapes, a combination of spheres (vesicles) and penny-shaped cracks (fractures) interpreted and quantified from petrographical data predicts the ultrasonic dry and saturated rock moduli for the measured basalts.

  4. Solid modeling research at Lawrence Livermore National Laboratory: 1982-1985

    Energy Technology Data Exchange (ETDEWEB)

    Kalibjian, J.R.

    1985-09-01

    The Lawrence Livermore National Laboratory has sponsored solid modeling research for the past four years to assess this new technology and to determine its potential benefits to the Nuclear Weapons Complex. We summarize here the results of five projects implemented during our effort. First, we have installed two solid modeler codes, TIPS-1 (Technical Information Processing System-1) and PADL-2 (Part and Assembly Description Language), on the Laboratory's CRAY-1 computers. Further, we have extended the geometric coverage and have enhanced the graphics capabilities of the TIPS-1 modeler. To enhance solid modeler performance on our OCTOPUS computer system, we have also developed a method to permit future use of the Laboratory's network video system to provide high-resolution, shaded images at users' locations. Finally, we have begun to implement code that will link solid-modeler data bases to finite-element meshing codes.

  5. Making animals alcoholic: shifting laboratory models of addiction.

    Science.gov (United States)

    Ramsden, Edmund

    2015-01-01

    The use of animals as experimental organisms has been critical to the development of addiction research from the nineteenth century. They have been used as a means of generating reliable data regarding the processes of addiction that was not available from the study of human subjects. Their use, however, has been far from straightforward. Through focusing on the study of alcoholism, where the nonhuman animal proved a most reluctant collaborator, this paper will analyze the ways in which scientists attempted to deal with its determined sobriety and account for their consistent failure to replicate the volitional consumption of ethanol to the point of physical dependency. In doing so, we will see how the animal model not only served as a means of interrogating a complex pathology, but also came to embody competing definitions of alcoholism as a disease process, and alternative visions for the very structure and purpose of a research field.

  6. Live streaming video for medical education: a laboratory model.

    Science.gov (United States)

    Gandsas, Alejandro; McIntire, Katherine; Palli, Guillermo; Park, Adrian

    2002-10-01

    At the University of Kentucky (UK), we applied streaming video technology to develop a webcast model that will allow institutions to broadcast live and prerecorded surgeries, conferences, and courses in real time over networks (the Internet or an intranet). We successfully broadcast a prerecorded laparoscopic paraesophageal hernia repair to domestic and international clients by using desktop computers equipped with off-the-shelf, streaming-enabled software and standard hardware and operating systems. A web-based user interface made accessing the educational material as simple as a mouse click and allowed clients to participate in the broadcast event via an embedded e-mail/chat module. Three client computers (two connected to the Internet and a third connected to the UK intranet) requested and displayed the surgical film by means of seven common network connection configurations. Significantly, no difference in image resolution was detected with the use of a connection speed faster than 128 kilobytes per second (kbps). At this connection speed, an average bandwidth of 32.7 kbps was used, and although a 15-second delay was experienced from the time of data request to data display, the surgical film streamed continuously from beginning to end at a mean rate of 14.4 frames per second (fps). The clients easily identified all anatomic structures in full color motion, clearly followed all steps of the surgical procedure, and successfully asked questions and made comments by using the e-mail/chat module while viewing the surgery. With minimal financial investment, we have created an interactive virtual classroom with the potential to attract a global audience. Our webcast model represents a simple and practical method for institutions to supplement undergraduate and graduate surgical education and offer continuing medical education credits in a way that is convenient for clients (surgeons, students, residents, others). In the future, physicians may access streaming webcast

  7. The Model Laboratory Animal and the‘Trojan Horse' in Biosecurity

    Institute of Scientific and Technical Information of China (English)

    Stephen Driver

    2003-01-01

    @@ Today's sophisticated biomedical research sometimes requires the use of laboratory animals raised in stable micronen vironments free from the microorganisms that may compromise the success of an experiment. Laboratory rodents can be obtained in one of several categories defined by the degree to which they harbour microflora, whether commensal, potentially pathogenic or pathogenic. It is now possible to specify the different species of organism that are tolerated and those that are not tolerated, In such model laboratory animals it is essential to raise and maintain them in circumstances under which microorganisms that would not be tolerated cannot enter the production system.

  8. Inertial waves in a laboratory model of the Earth's core

    Science.gov (United States)

    Triana, Santiago Andres

    2011-12-01

    A water-filled three-meter diameter spherical shell built as a model of the Earth's core shows evidence of precessionally forced flows and, when spinning the inner sphere differentially, inertial modes are excited. We identified the precessionally forced flow to be primarily the spin-over inertial mode, i.e., a uniform vorticity flow whose rotation axis is not aligned with the container's rotation axis. A systematic study of the spin-over mode is carried out, showing that the amplitude dependence on the Poincare number is in qualitative agreement with Busse's laminar theory while its phase differs significantly, likely due to topographic effects. At high rotation rates free shear layers concentrating most of the kinetic energy of the spin-over mode have been observed. When spinning the inner sphere differentially, a total of 12 inertial modes have been identified, reproducing and extending previous experimental results. The inertial modes excited appear ordered according to their azimuthal drift speed as the Rossby number is varied.

  9. Understanding Dynamics of Information Transmission in Drosophila melanogaster Using a Statistical Modeling Framework for Longitudinal Network Data (the RSiena Package)

    Science.gov (United States)

    Pasquaretta, Cristian; Klenschi, Elizabeth; Pansanel, Jérôme; Battesti, Marine; Mery, Frederic; Sueur, Cédric

    2016-01-01

    Social learning – the transmission of behaviors through observation or interaction with conspecifics – can be viewed as a decision-making process driven by interactions among individuals. Animal group structures change over time and interactions among individuals occur in particular orders that may be repeated following specific patterns, change in their nature, or disappear completely. Here we used a stochastic actor-oriented model built using the RSiena package in R to estimate individual behaviors and their changes through time, by analyzing the dynamic of the interaction network of the fruit fly Drosophila melanogaster during social learning experiments. In particular, we re-analyzed an experimental dataset where uninformed flies, left free to interact with informed ones, acquired and later used information about oviposition site choice obtained by social interactions. We estimated the degree to which the uninformed flies had successfully acquired the information carried by informed individuals using the proportion of eggs laid by uninformed flies on the medium their conspecifics had been trained to favor. Regardless of the degree of information acquisition measured in uninformed individuals, they always received and started interactions more frequently than informed ones did. However, information was efficiently transmitted (i.e., uninformed flies predominantly laid eggs on the same medium informed ones had learn to prefer) only when the difference in contacts sent between the two fly types was small. Interestingly, we found that the degree of reciprocation, the tendency of individuals to form mutual connections between each other, strongly affected oviposition site choice in uninformed flies. This work highlights the great potential of RSiena and its utility in the studies of interaction networks among non-human animals. PMID:27148146

  10. Understanding dynamics of information transmission in Drosophila melanogaster using a statistical modeling framework for longitudinal network data (the RSiena package

    Directory of Open Access Journals (Sweden)

    Cristian ePasquaretta

    2016-04-01

    Full Text Available Social learning – the transmission of behaviors through observation or interaction with conspecifics – can be viewed as a decision-making process driven by interactions among individuals. Animal group structures change over time and interactions among individuals occur in particular orders that may be repeated following specific patterns, change in their nature, or disappear completely. Here we used a stochastic actor-oriented model built using the RSiena package in R to estimate individual behaviors and their changes through time, by analyzing the dynamic of the interaction network of the fruit fly Drosophila melanogaster during social learning experiments. In particular, we re-analyzed an experimental dataset where uninformed flies, left free to interact with informed ones, acquired and later used information about oviposition site choice obtained by social interactions. We estimated the degree to which the uninformed flies had successfully acquired the information carried by informed individuals using the proportion of eggs laid by uninformed flies on the medium their conspecifics had been trained to favor. Regardless of the degree of information acquisition measured in uninformed individuals, they always received and started interactions more frequently than informed ones did. However, information was efficiently transmitted (i.e. uninformed flies predominantly laid eggs on the same medium informed ones had learn to prefer only when the difference in contacts sent between the two fly types was small. Interestingly, we found that the degree of reciprocation, the tendency of individuals to form mutual connections between each other, strongly affected oviposition site choice in uninformed flies. This work highlights the great potential of RSiena and its utility in the studies of interaction networks among non-human animals.

  11. An Integrated Visualization and Basic Molecular Modeling Laboratory for First-Year Undergraduate Medicinal Chemistry

    Science.gov (United States)

    Hayes, Joseph M.

    2014-01-01

    A 3D model visualization and basic molecular modeling laboratory suitable for first-year undergraduates studying introductory medicinal chemistry is presented. The 2 h practical is embedded within a series of lectures on drug design, target-drug interactions, enzymes, receptors, nucleic acids, and basic pharmacokinetics. Serving as a teaching aid…

  12. An Integrated Visualization and Basic Molecular Modeling Laboratory for First-Year Undergraduate Medicinal Chemistry

    Science.gov (United States)

    Hayes, Joseph M.

    2014-01-01

    A 3D model visualization and basic molecular modeling laboratory suitable for first-year undergraduates studying introductory medicinal chemistry is presented. The 2 h practical is embedded within a series of lectures on drug design, target-drug interactions, enzymes, receptors, nucleic acids, and basic pharmacokinetics. Serving as a teaching aid…

  13. Signal processor packaging design

    Science.gov (United States)

    McCarley, Paul L.; Phipps, Mickie A.

    1993-10-01

    The Signal Processor Packaging Design (SPPD) program was a technology development effort to demonstrate that a miniaturized, high throughput programmable processor could be fabricated to meet the stringent environment imposed by high speed kinetic energy guided interceptor and missile applications. This successful program culminated with the delivery of two very small processors, each about the size of a large pin grid array package. Rockwell International's Tactical Systems Division in Anaheim, California developed one of the processors, and the other was developed by Texas Instruments' (TI) Defense Systems and Electronics Group (DSEG) of Dallas, Texas. The SPPD program was sponsored by the Guided Interceptor Technology Branch of the Air Force Wright Laboratory's Armament Directorate (WL/MNSI) at Eglin AFB, Florida and funded by SDIO's Interceptor Technology Directorate (SDIO/TNC). These prototype processors were subjected to rigorous tests of their image processing capabilities, and both successfully demonstrated the ability to process 128 X 128 infrared images at a frame rate of over 100 Hz.

  14. Flow in the Ebro Delta shelf, Numerical models and laboratory simulations

    Science.gov (United States)

    Carrillo, A.; Fraunie, P.; Durand, N.

    2009-04-01

    This work presents the results of two laboratory and numerical experiments. The characteristic induced structures by stationer typical conditions from spring, summer, fall and winter. Laboratory experiences were developed on a five meters turntable (SINTEF facilities) obeys the Froude-Rossby similarities. While, the meso-escale numerical model was developed in the LSEET laboratory. This work evidences complementary results from the vortex sort characteristic by radius from both experimental and model methods. Additionally numerical model has a better representation from the conditions in the first 15km and the laboratory model represent the resolution between the large and the meso scale boundary. Physical variables that describe mixing are compared with experimental laboratory results from a large number of studies of mixing dynamics in environmental fluids to find habitat regimes for primary production. The work relates physical and biological variables, and emphasises the utility of laboratory studies. Several laboratory experiments that focused on turbulent mixing dynamics in stratified shear flows are used to describe (a) mixing in the estuary and (b) induced circulation in the river plume. Mixing descriptors as entrainment, Richardson number and Reynolds number and field data were employed, and advanced techniques of laboratory simulations, image processing and numerical modelling were used to match (a) to (b). Four kinds of experiments were used to describe the dynamics in the whole estuary. Mixing turbulence across a density interface generated by an oscillating grid inside a mixing-box. The horizontal advance of a turbulent front in a stratified system with a lateral current, inside a 1 m x 1 m square box. Induced circulation in the delta del Ebro slope and shelf that were performed with an experimental model in a 2 m x 4 m rectangular tank on a 5-m diameter turntable. Dispersion simulations in the river plume with the OCK3D code. Experiments were

  15. Hydropower computerized reconnaissance package version 2. 0. [HYDRO-CAL, PAPER-ECON, and HYDRO-ECON

    Energy Technology Data Exchange (ETDEWEB)

    Broadus, C.R.

    1981-04-01

    The Hydropower Computerized Reconnaissance (HCR) Package is a computerized preliminary engineering and economic study package for small hydroelectric projects which consists of three programs developed at the Idaho National Engineering Laboratory. One engineering program evaluates the flow characteristics of a site and determines the energy generated for various turbine configurations and two economic programs provide two levels of economic studies depending upon the amount of site-specific information available. An Apple II computer is utilized to provide a quick-turnaround capability. The models and methods used in the HCR package are described, and information is provided on program application, sample run sessions, program outputs, and listings of the main programs.

  16. Population stochastic modelling (PSM)-An R package for mixed-effects models based on stochastic differential equations

    DEFF Research Database (Denmark)

    Klim, Søren; Mortensen, Stig Bousgaard; Kristensen, Niels Rode

    2009-01-01

    likelihood estimation of a time-inhomogeneous stochastic differential model of glucose dynamics, Math. Med. Biol. 25 (June(2)) (2008) 141-155]. PK/PD models are traditionally based ordinary differential equations (ODES) with an observation link that incorporates noise. This state-space formulation only......The extension from ordinary to stochastic differential equations (SDEs) in pharmacokinetic and pharmacodynamic (PK/PD) modelling is an emerging field and has been motivated in a number of articles [N.R. Kristensen, H. Madsen, S.H. Ingwersen, Using stochastic differential equations for PK/PD model...... development, J. Pharmacokinet. Pharmacodyn. 32 (February(l)) (2005) 109-141; C.W. Tornoe, R.V Overgaard, H. Agerso, H.A. Nielsen, H. Madsen, E.N. Jonsson, Stochastic differential equations in NONMEM: implementation, application, and comparison with ordinary differential equations, Pharm. Res. 22 (August(8...

  17. Development of collaborative-creative learning model using virtual laboratory media for instrumental analytical chemistry lectures

    Science.gov (United States)

    Zurweni, Wibawa, Basuki; Erwin, Tuti Nurian

    2017-08-01

    The framework for teaching and learning in the 21st century was prepared with 4Cs criteria. Learning providing opportunity for the development of students' optimal creative skills is by implementing collaborative learning. Learners are challenged to be able to compete, work independently to bring either individual or group excellence and master the learning material. Virtual laboratory is used for the media of Instrumental Analytical Chemistry (Vis, UV-Vis-AAS etc) lectures through simulations computer application and used as a substitution for the laboratory if the equipment and instruments are not available. This research aims to design and develop collaborative-creative learning model using virtual laboratory media for Instrumental Analytical Chemistry lectures, to know the effectiveness of this design model adapting the Dick & Carey's model and Hannafin & Peck's model. The development steps of this model are: needs analyze, design collaborative-creative learning, virtual laboratory media using macromedia flash, formative evaluation and test of learning model effectiveness. While, the development stages of collaborative-creative learning model are: apperception, exploration, collaboration, creation, evaluation, feedback. Development of collaborative-creative learning model using virtual laboratory media can be used to improve the quality learning in the classroom, overcome the limitation of lab instruments for the real instrumental analysis. Formative test results show that the Collaborative-Creative Learning Model developed meets the requirements. The effectiveness test of students' pretest and posttest proves significant at 95% confidence level, t-test higher than t-table. It can be concluded that this learning model is effective to use for Instrumental Analytical Chemistry lectures.

  18. Integrated software packages in the physical laboratory

    Science.gov (United States)

    Bok, J.; Barvík, I.; Praus, P.; Heřman, P.; Čermáková, D.

    1990-11-01

    The automation of a UV-VIS spectrometer and a single-photon counting apparatus by an IBM-AT is described. Software needed for the computer control, data acquisition and processing was developed in the ASYST environment. This enabled us to use its very good graphics, its support of I/O cards, and its other excellent properties. Also we show ways to overcome some minor shortcomings using the multilanguage programming.

  19. A Simple Laboratory Scale Model of Iceberg Dynamics and its Role in Undergraduate Education

    Science.gov (United States)

    Burton, J. C.; MacAyeal, D. R.; Nakamura, N.

    2011-12-01

    Lab-scale models of geophysical phenomena have a long history in research and education. For example, at the University of Chicago, Dave Fultz developed laboratory-scale models of atmospheric flows. The results from his laboratory were so stimulating that similar laboratories were subsequently established at a number of other institutions. Today, the Dave Fultz Memorial Laboratory for Hydrodynamics (http://geosci.uchicago.edu/~nnn/LAB/) teaches general circulation of the atmosphere and oceans to hundreds of students each year. Following this tradition, we have constructed a lab model of iceberg-capsize dynamics for use in the Fultz Laboratory, which focuses on the interface between glaciology and physical oceanography. The experiment consists of a 2.5 meter long wave tank containing water and plastic "icebergs". The motion of the icebergs is tracked using digital video. Movies can be found at: http://geosci.uchicago.edu/research/glaciology_files/tsunamigenesis_research.shtml. We have had 3 successful undergraduate interns with backgrounds in mathematics, engineering, and geosciences perform experiments, analyze data, and interpret results. In addition to iceberg dynamics, the wave-tank has served as a teaching tool in undergraduate classes studying dam-breaking and tsunami run-up. Motivated by the relatively inexpensive cost of our apparatus (~1K-2K dollars) and positive experiences of undergraduate students, we hope to serve as a model for undergraduate research and education that other universities may follow.

  20. DNA packaging by lambda-like bacteriophages: mutations broadening the packaging specificity of terminase, the lambda-packaging enzyme.

    Science.gov (United States)

    Feiss, Michael; Reynolds, Erin; Schrock, Morgan; Sippy, Jean

    2010-01-01

    The DNA-packaging specificities of phages lambda and 21 depend on the specific DNA interactions of the small terminase subunits, which have support helix-turn-recognition helix-wing DNA-binding motifs. lambda-Terminase with the recognition helix of 21 preferentially packages 21 DNA. This chimeric terminase's ability to package lambdaDNA is reduced approximately 20-fold. Phage lambda with the chimeric terminase is unable to form plaques, but pseudorevertants are readily obtained. Some pseudorevertants have trans-acting suppressors that change codons of the recognition helix. Some of these codons appear to remove an unfavorable base-pair contact; others appear to create a novel nonspecific DNA contact. Helper-packaging experiments show that these mutant terminases have lost the ability to discriminate between lambda and 21 during DNA packaging. Two cis-acting suppressors affect cosB, the small subunit's DNA-binding site. Each changes a cosB(lambda)-specific base pair to a cosB(21)-specific base pair. These cosB suppressors cause enhanced DNA packaging by 21-specific terminase and reduce packaging by lambda-terminase. Both the cognate support helix and turn are required for strong packaging discrimination. The wing does not contribute to cosB specificity. Evolution of packaging specificity is discussed, including a model in which lambda- and 21-packaging specificities diverged from a common ancestor phage with broad packaging specificity.

  1. DNA Packaging by λ-Like Bacteriophages: Mutations Broadening the Packaging Specificity of Terminase, the λ-Packaging Enzyme

    Science.gov (United States)

    Feiss, Michael; Reynolds, Erin; Schrock, Morgan; Sippy, Jean

    2010-01-01

    The DNA-packaging specificities of phages λ and 21 depend on the specific DNA interactions of the small terminase subunits, which have support helix-turn-recognition helix-wing DNA-binding motifs. λ-Terminase with the recognition helix of 21 preferentially packages 21 DNA. This chimeric terminase's ability to package λDNA is reduced ∼20-fold. Phage λ with the chimeric terminase is unable to form plaques, but pseudorevertants are readily obtained. Some pseudorevertants have trans-acting suppressors that change codons of the recognition helix. Some of these codons appear to remove an unfavorable base-pair contact; others appear to create a novel nonspecific DNA contact. Helper-packaging experiments show that these mutant terminases have lost the ability to discriminate between λ and 21 during DNA packaging. Two cis-acting suppressors affect cosB, the small subunit's DNA-binding site. Each changes a cosBλ-specific base pair to a cosB21-specific base pair. These cosB suppressors cause enhanced DNA packaging by 21-specific terminase and reduce packaging by λ-terminase. Both the cognate support helix and turn are required for strong packaging discrimination. The wing does not contribute to cosB specificity. Evolution of packaging specificity is discussed, including a model in which λ- and 21-packaging specificities diverged from a common ancestor phage with broad packaging specificity. PMID:19841094

  2. 9977 TYPE B PACKAGING INTERNAL DATA COLLECTION FEASIBILITY TESTING - MAGNETIC FIELD COMMUNICATIONS

    Energy Technology Data Exchange (ETDEWEB)

    Shull, D.

    2012-06-18

    The objective of this report is to document the findings from proof-of-concept testing performed by the Savannah River National Laboratory (SRNL) R&D Engineering and Visible Assets, Inc. for the DOE Packaging Certification Program (PCP) to determine if RuBee (IEEE 1902.1) tags and readers could be used to provide a communication link from within a drum-style DOE certified Type B radioactive materials packaging. A Model 9977 Type B Packaging was used to test the read/write capability and range performance of a RuBee tag and reader. Testing was performed with the RuBee tags placed in various locations inside the packaging including inside the drum on the outside of the lid of the containment vessel and also inside of the containment vessel. This report documents the test methods and results. A path forward will also be recommended.

  3. Aquarius - A Modelling Package for Groundwater Flow and Coupled Heat Transport in the Range 0.1 to 100 MPa and 0.1 to 1000 C

    Science.gov (United States)

    Cook, S. J.

    2009-05-01

    Aquarius is a Windows application that models fluid flow and heat transport under conditions in which fluid buoyancy can significantly impact patterns and magnitudes of fluid flow. The package is designed as a visualization tool through which users can examine flow systems in environments, both low temperature aquifers and regions with elevated PT regimes such as deep sedimentary basins, hydrothermal systems, and contact thermal aureoles. The package includes 4 components: (1) A finite-element mesh generator/assembler capable of representing complex geologic structures. Left-hand, right-hand and alternating linear triangles can be mixed within the mesh. Planer horizontal, planer vertical and cylindrical vertical coordinate sections are supported. (2) A menu-selectable system for setting properties and boundary/initial conditions. The design retains mathematical terminology for all input parameters such as scalars (e.g., porosity), tensors (e.g., permeability), and boundary/initial conditions (e.g., fixed potential). This makes the package an effective instructional aide by linking model requirements with the underlying mathematical concepts of partial differential equations and the solution logic of boundary/initial value problems. (3) Solution algorithms for steady-state and time-transient fluid flow/heat transport problems. For all models, the nonlinear global matrix equations are solved sequentially using over-relaxation techniques. Matrix storage design allows for large (e.g., 20000) element models to run efficiently on a typical PC. (4) A plotting system that supports contouring nodal data (e.g., head), vector plots for flux data (e.g., specific discharge), and colour gradient plots for elemental data (e.g., porosity), water properties (e.g., density), and performance measures (e.g., Peclet numbers). Display graphics can be printed or saved in standard graphic formats (e.g., jpeg). This package was developed from procedural codes in C written originally to

  4. Useful measures and models for analytical quality management in medical laboratories.

    Science.gov (United States)

    Westgard, James O

    2016-02-01

    The 2014 Milan Conference "Defining analytical performance goals 15 years after the Stockholm Conference" initiated a new discussion of issues concerning goals for precision, trueness or bias, total analytical error (TAE), and measurement uncertainty (MU). Goal-setting models are critical for analytical quality management, along with error models, quality-assessment models, quality-planning models, as well as comprehensive models for quality management systems. There are also critical underlying issues, such as an emphasis on MU to the possible exclusion of TAE and a corresponding preference for separate precision and bias goals instead of a combined total error goal. This opinion recommends careful consideration of the differences in the concepts of accuracy and traceability and the appropriateness of different measures, particularly TAE as a measure of accuracy and MU as a measure of traceability. TAE is essential to manage quality within a medical laboratory and MU and trueness are essential to achieve comparability of results across laboratories. With this perspective, laboratory scientists can better understand the many measures and models needed for analytical quality management and assess their usefulness for practical applications in medical laboratories.

  5. CANE FIBERBOARD DEGRADATION WITHIN THE 9975 SHIPPING PACKAGE DURING LONG-TERM STORAGE APPLICATION

    Energy Technology Data Exchange (ETDEWEB)

    Daugherty, W.; Dunn, K.; Hackney, B.

    2013-06-19

    The 9975 shipping package is used as part of the configuration for long-term storage of special nuclear materials in the K Area Complex at the Savannah River Site. The cane fiberboard overpack in the 9975 package provides thermal insulation, impact absorption and criticality control functions relevant to this application. The Savannah River National Laboratory has conducted physical, mechanical and thermal tests on aged fiberboard samples to identify degradation rates and support the development of aging models and service life predictions in a storage environment. This paper reviews the data generated to date, and preliminary models describing degradation rates of cane fiberboard in elevated temperature – elevated humidity environments.

  6. PRIDE Surveillance Projects Data Packaging Project Information Package Specification Version 1.1

    Energy Technology Data Exchange (ETDEWEB)

    Kelleher, D. M.; Shipp, R. L.; Mason, J. D.

    2010-08-31

    Information Package Specification version 1.1 describes an XML document format called an information package that can be used to store information in information management systems and other information archives. An information package consists of package information, the context required to understand and use that information, package metadata that describes the information, and XML signatures that protect the information. The information package described in this specification was designed to store Department of Energy (DOE) and National Nuclear Security Administration (NNSA) information and includes the metadata required for that information: a unique package identifier, information marking that conforms to DOE and NNSA requirements, and access control metadata. It is an implementation of the Open Archival Information System (OAIS) Reference Model archival information package tailored to meet NNSA information storage requirements and designed to be used in the computing environments at the Y-12 National Security Complex and at other NNSA sites.

  7. Challenges in the Packaging of MEMS

    Energy Technology Data Exchange (ETDEWEB)

    Malshe, A.P.; Singh, S.B.; Eaton, W.P.; O' Neal, C.; Brown, W.D.; Miller, W.M.

    1999-03-26

    gross lack of understanding between the package materials, induced stress, and the device performance. The material properties of these packaging materials are not well defined or understood. Modeling of these materials and processes is far from maturity. Current post-package yields are too low for commercial feasibility, and consumer operating environment reliability and compatibility are often difficult to simulate. With further understanding of the materials properties and behavior of the packaging materials, MEMS applications can be fully realized and integrated into countless commercial and military applications.

  8. Challenges in the Packaging of MEMS

    Energy Technology Data Exchange (ETDEWEB)

    Malshe, A.P.; Singh, S.B.; Eaton, W.P.; O' Neal, C.; Brown, W.D.; Miller, W.M.

    1999-03-26

    gross lack of understanding between the package materials, induced stress, and the device performance. The material properties of these packaging materials are not well defined or understood. Modeling of these materials and processes is far from maturity. Current post-package yields are too low for commercial feasibility, and consumer operating environment reliability and compatibility are often difficult to simulate. With further understanding of the materials properties and behavior of the packaging materials, MEMS applications can be fully realized and integrated into countless commercial and military applications.

  9. Long-term behaviour of concrete: development of operational model to predict the evolution of its containment performance. Application to cemented waste packages

    Energy Technology Data Exchange (ETDEWEB)

    Peycelon, H.; Le Bescop, P.; Richet, C. [CEA Saclay, Dept. de Physico-Chimie, DPC, 91 - Gif-sur-Yvette (France); Adenot, F. [CEA Cadarache, 13 - Saint Paul lez Durance (France). Dept. d' Entreposage et de Stockage des Dechets; Blanc, V. [Cogema, 78 - Saint Quentin en Yvelines (France)

    2001-07-01

    In order to describe the main phenomena during different stages of cement waste packages life-time and to predict the long-term behaviour (containment performance) of concrete, coupled experiments and modelling studies are achieved. With respect to logical methodology, improvement of these studies is accomplished. Degradation of concrete in low mineralized, carbonated and sulfated water lead to an evolution of chemical characteristics (dissolution/precipitation of solid phases) and of transport properties which must be included or coupled in retention/transport modelling of radio nuclides to predict containment performance. (author)

  10. Nonparametric Econometrics: The np Package

    Directory of Open Access Journals (Sweden)

    Tristen Hayfield

    2008-07-01

    Full Text Available We describe the R np package via a series of applications that may be of interest to applied econometricians. The np package implements a variety of nonparametric and semiparametric kernel-based estimators that are popular among econometricians. There are also procedures for nonparametric tests of significance and consistent model specification tests for parametric mean regression models and parametric quantile regression models, among others. The np package focuses on kernel methods appropriate for the mix of continuous, discrete, and categorical data often found in applied settings. Data-driven methods of bandwidth selection are emphasized throughout, though we caution the user that data-driven bandwidth selection methods can be computationally demanding.

  11. actuar: An R Package for Actuarial Science

    Directory of Open Access Journals (Sweden)

    Christophe Dutang

    2008-02-01

    Full Text Available actuar is a package providing additional Actuarial Science functionality to the R statistical system. The project was launched in 2005 and the package is available on the Comprehensive R Archive Network since February 2006. The current version of the package contains functions for use in the fields of loss distributions modeling, risk theory (including ruin theory, simulation of compound hierarchical models and credibility theory. This paper presents in detail but with few technical terms the most recent version of the package.

  12. Dissolved carbon dioxide and oxygen concentrations in purge of vacuum-packaged pork chops and the relationship to shelf life and models for estimating microbial populations.

    Science.gov (United States)

    Adams, K R; Niebuhr, S E; Dickson, J S

    2015-12-01

    The objectives of this study were to determine the dissolved CO2 and O2 concentrations in the purge of vacuum-packaged pork chops over a 60 day storage period, and to elucidate the relationship of dissolved CO2 and O2 to the microbial populations and shelf life. As the populations of spoilage bacteria increased, the dissolved CO2 increased and the dissolved O2 decreased in the purge. Lactic acid bacteria dominated the spoilage microflora, followed by Enterobacteriaceae and Brochothrix thermosphacta. The surface pH decreased to 5.4 due to carbonic acid and lactic acid production before rising to 5.7 due to ammonia production. A mathematical model was developed which estimated microbial populations based on dissolved CO2 concentrations. Scanning electron microscope images were also taken of the packaging film to observe the biofilm development. The SEM images revealed a two-layer biofilm on the packaging film that was the result of the tri-phase growth environment. Copyright © 2015 Elsevier Ltd. All rights reserved.

  13. A Laboratory Exercise Using a Physical Model for Demonstrating Countercurrent Heat Exchange

    Science.gov (United States)

    Loudon, Catherine; Davis-Berg, Elizabeth C.; Botz, Jason T.

    2012-01-01

    A physical model was used in a laboratory exercise to teach students about countercurrent exchange mechanisms. Countercurrent exchange is the transport of heat or chemicals between fluids moving in opposite directions separated by a permeable barrier (such as blood within adjacent blood vessels flowing in opposite directions). Greater exchange of…

  14. 3D Printing of Protein Models in an Undergraduate Laboratory: Leucine Zippers

    Science.gov (United States)

    Meyer, Scott C.

    2015-01-01

    An upper-division undergraduate laboratory experiment is described that explores the structure/function relationship of protein domains, namely leucine zippers, through a molecular graphics computer program and physical models fabricated by 3D printing. By generating solvent accessible surfaces and color-coding hydrophobic, basic, and acidic amino…

  15. Implementation of Argument-Driven Inquiry as an Instructional Model in a General Chemistry Laboratory Course

    Science.gov (United States)

    Kadayifci, Hakki; Yalcin-Celik, Ayse

    2016-01-01

    This study examined the effectiveness of Argument-Driven Inquiry (ADI) as an instructional model in a general chemistry laboratory course. The study was conducted over the course of ten experimental sessions with 125 pre-service science teachers. The participants' level of reflective thinking about the ADI activities, changes in their science…

  16. Design and Study of a Low-Cost Laboratory Model Digital Wind Power Meter

    Science.gov (United States)

    Radhakrishnan, Rugmini; Karthika, S.

    2010-01-01

    A vane-type low-cost laboratory model anemometer cum power meter is designed and constructed for measuring low wind energy created from accelerating fluids. The constructed anemometer is a device which records the electrical power obtained by the conversion of wind power using a wind sensor coupled to a DC motor. It is designed for its…

  17. Coupling Molecular Modeling to the Traditional "IR-ID" Exercise in the Introductory Organic Chemistry Laboratory

    Science.gov (United States)

    Stokes-Huby, Heather; Vitale, Dale E.

    2007-01-01

    This exercise integrates the infrared unknown identification ("IR-ID") experiment common to most organic laboratory syllabi with computer molecular modeling. In this modification students are still required to identify unknown compounds from their IR spectra, but must additionally match some of the absorptions with computed frequencies they…

  18. Examination of Bond Properties through Infrared Spectroscopy and Molecular Modeling in the General Chemistry Laboratory

    Science.gov (United States)

    Csizmar, Clifford M.; Force, Dee Ann; Warner, Don L.

    2012-01-01

    A concerted effort has been made to increase the opportunities for undergraduate students to address scientific problems employing the processes used by practicing chemists. As part of this effort, an infrared (IR) spectroscopy and molecular modeling experiment was developed for the first-year general chemistry laboratory course. In the…

  19. Laboratory-based grain-shape models for simulating dust infrared spectra

    NARCIS (Netherlands)

    Mutschke, H.; Min, M.; Tamanai, A.

    2009-01-01

    Context. Analysis of thermal dust emission spectra for dust mineralogy and physical grain properties depends on comparison spectra, which are either laboratory-measured infrared extinction spectra or calculated extinction cross sections based on certain grain models. Often, the agreement between the

  20. A Laboratory Exercise Using a Physical Model for Demonstrating Countercurrent Heat Exchange

    Science.gov (United States)

    Loudon, Catherine; Davis-Berg, Elizabeth C.; Botz, Jason T.

    2012-01-01

    A physical model was used in a laboratory exercise to teach students about countercurrent exchange mechanisms. Countercurrent exchange is the transport of heat or chemicals between fluids moving in opposite directions separated by a permeable barrier (such as blood within adjacent blood vessels flowing in opposite directions). Greater exchange of…

  1. 3D Printing of Protein Models in an Undergraduate Laboratory: Leucine Zippers

    Science.gov (United States)

    Meyer, Scott C.

    2015-01-01

    An upper-division undergraduate laboratory experiment is described that explores the structure/function relationship of protein domains, namely leucine zippers, through a molecular graphics computer program and physical models fabricated by 3D printing. By generating solvent accessible surfaces and color-coding hydrophobic, basic, and acidic amino…

  2. Modeling Soil Organic Carbon at Regional Scale by Combining Multi-Spectral Images with Laboratory Spectra

    DEFF Research Database (Denmark)

    Peng, Yi; Xiong, Xiong; Adhikari, Kabindra

    2015-01-01

    results by separately modeling uplands and wetlands. A total of 328 topsoil samples were collected and analyzed for SOC. Satellite Pour l’Observation de la Terre (SPOT5), Landsat Data Continuity Mission (Landsat 8) images, laboratory Vis-NIR and other ancillary environmental data including terrain...

  3. Design and Study of a Low-Cost Laboratory Model Digital Wind Power Meter

    Science.gov (United States)

    Radhakrishnan, Rugmini; Karthika, S.

    2010-01-01

    A vane-type low-cost laboratory model anemometer cum power meter is designed and constructed for measuring low wind energy created from accelerating fluids. The constructed anemometer is a device which records the electrical power obtained by the conversion of wind power using a wind sensor coupled to a DC motor. It is designed for its…

  4. Examination of Bond Properties through Infrared Spectroscopy and Molecular Modeling in the General Chemistry Laboratory

    Science.gov (United States)

    Csizmar, Clifford M.; Force, Dee Ann; Warner, Don L.

    2012-01-01

    A concerted effort has been made to increase the opportunities for undergraduate students to address scientific problems employing the processes used by practicing chemists. As part of this effort, an infrared (IR) spectroscopy and molecular modeling experiment was developed for the first-year general chemistry laboratory course. In the…

  5. Model-based fuzzy control solutions for a laboratory Antilock Braking System

    DEFF Research Database (Denmark)

    Precup, Radu-Emil; Spataru, Sergiu; Rǎdac, Mircea-Bogdan;

    2010-01-01

    This paper gives two original model-based fuzzy control solutions dedicated to the longitudinal slip control of Antilock Braking System laboratory equipment. The parallel distributed compensation leads to linear matrix inequalities which guarantee the global stability of the fuzzy control systems...

  6. Model-based reasoning in the physics laboratory: Framework and initial results

    Science.gov (United States)

    Zwickl, Benjamin M.; Hu, Dehui; Finkelstein, Noah; Lewandowski, H. J.

    2015-12-01

    [This paper is part of the Focused Collection on Upper Division Physics Courses.] We review and extend existing frameworks on modeling to develop a new framework that describes model-based reasoning in introductory and upper-division physics laboratories. Constructing and using models are core scientific practices that have gained significant attention within K-12 and higher education. Although modeling is a broadly applicable process, within physics education, it has been preferentially applied to the iterative development of broadly applicable principles (e.g., Newton's laws of motion in introductory mechanics). A significant feature of the new framework is that measurement tools (in addition to the physical system being studied) are subjected to the process of modeling. Think-aloud interviews were used to refine the framework and demonstrate its utility by documenting examples of model-based reasoning in the laboratory. When applied to the think-aloud interviews, the framework captures and differentiates students' model-based reasoning and helps identify areas of future research. The interviews showed how students productively applied similar facets of modeling to the physical system and measurement tools: construction, prediction, interpretation of data, identification of model limitations, and revision. Finally, we document students' challenges in explicitly articulating assumptions when constructing models of experimental systems and further challenges in model construction due to students' insufficient prior conceptual understanding. A modeling perspective reframes many of the seemingly arbitrary technical details of measurement tools and apparatus as an opportunity for authentic and engaging scientific sense making.

  7. Release Data Package for Hanford Site Assessments

    Energy Technology Data Exchange (ETDEWEB)

    Riley, Robert G.; Lopresti, Charles A.; Engel, David W.

    2006-07-01

    Beginning in fiscal year (FY) 2003, the U.S. Department of Energy (DOE) Richland Operations Office initiated activities, including the development of data packages, to support a Hanford assessment. This report describes the data compiled in FY 2003 through 2005 to support the Release Module of the System Assessment Capability (SAC) for the updated composite analysis. This work was completed as part of the Characterization of Systems Project, part of the Remediation and Closure Science Project, the Hanford Assessments Project, and the Characterization of Systems Project managed by Pacific Northwest National Laboratory. Related characterization activities and data packages for the vadose zone and groundwater are being developed under the remediation Decision Support Task of the Groundwater Remediation Project managed by Fluor Hanford, Inc. The Release Module applies release models to waste inventory data from the Inventory Module and accounts for site remediation activities as a function of time. The resulting releases to the vadose zone, expressed as time profiles of annual rates, become source terms for the Vadose Zone Module. Radioactive decay is accounted for in all inputs and outputs of the Release Module. The Release Module is implemented as the VADER (Vadose zone Environmental Release) computer code. Key components of the Release Module are numerical models (i.e., liquid, soil-debris, cement, saltcake, and reactor block) that simulate contaminant release from the different waste source types found at the Hanford Site. The Release Module also handles remediation transfers to onsite and offsite repositories.

  8. Training package 1 for slitting data analysis

    Energy Technology Data Exchange (ETDEWEB)

    Prime, Michael Bruce [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-03-23

    This document and accompanying files are intended as a first training package on how to analyze slitting data. The end goal is to have Idaho National Laboratory (INL) personnel trained to analyze future slitting data taken in the INL Hot Cell on clad, Low-Enriched Uranium (LEU) fuel plates. This first data package will cover data analysis for a monolithic material (as compared to a layered material like the clad fuel plates). The additional issues for layered specimens will be covered in a future training package.

  9. Modular optimization code package: MOZAIK

    Science.gov (United States)

    Bekar, Kursat B.

    This dissertation addresses the development of a modular optimization code package, MOZAIK, for geometric shape optimization problems in nuclear engineering applications. MOZAIK's first mission, determining the optimal shape of the D2O moderator tank for the current and new beam tube configurations for the Penn State Breazeale Reactor's (PSBR) beam port facility, is used to demonstrate its capabilities and test its performance. MOZAIK was designed as a modular optimization sequence including three primary independent modules: the initializer, the physics and the optimizer, each having a specific task. By using fixed interface blocks among the modules, the code attains its two most important characteristics: generic form and modularity. The benefit of this modular structure is that the contents of the modules can be switched depending on the requirements of accuracy, computational efficiency, or compatibility with the other modules. Oak Ridge National Laboratory's discrete ordinates transport code TORT was selected as the transport solver in the physics module of MOZAIK, and two different optimizers, Min-max and Genetic Algorithms (GA), were implemented in the optimizer module of the code package. A distributed memory parallelism was also applied to MOZAIK via MPI (Message Passing Interface) to execute the physics module concurrently on a number of processors for various states in the same search. Moreover, dynamic scheduling was enabled to enhance load balance among the processors while running MOZAIK's physics module thus improving the parallel speedup and efficiency. In this way, the total computation time consumed by the physics module is reduced by a factor close to M, where M is the number of processors. This capability also encourages the use of MOZAIK for shape optimization problems in nuclear applications because many traditional codes related to radiation transport do not have parallel execution capability. A set of computational models based on the

  10. Laboratory Experiments on Steady State Seepage-Induced Landslides Using Slope Models and Sensors

    OpenAIRE

    Sandra G. Catane; Mark Albert H. Zarco; Cathleen Joyce N. Cordero; Roy Albert N. Kaimo; Ricarido M. Saturay, Jr.

    2011-01-01

    A thorough understanding of the failure initiation process is crucial in the development of physicallybased early warning system for landslides and slope failures. Laboratory-scale slope models were constructed and subjected to instability through simulated groundwater infiltration. This is done by progressively increasing the water level in the upslope tank and allowing water to infiltrate laterally towards the toe of the slope. Physical changes in the slope models were recorded by tilt sens...

  11. Should hydraulic tomography data be interpreted using geostatistical inverse modeling? A laboratory sandbox investigation

    Science.gov (United States)

    Illman, Walter A.; Berg, Steven J.; Zhao, Zhanfeng

    2015-05-01

    The robust performance of hydraulic tomography (HT) based on geostatistics has been demonstrated through numerous synthetic, laboratory, and field studies. While geostatistical inverse methods offer many advantages, one key disadvantage is its highly parameterized nature, which renders it computationally intensive for large-scale problems. Another issue is that geostatistics-based HT may produce overly smooth images of subsurface heterogeneity when there are few monitoring interval data. Therefore, some may question the utility of the geostatistical inversion approach in certain situations and seek alternative approaches. To investigate these issues, we simultaneously calibrated different groundwater models with varying subsurface conceptualizations and parameter resolutions using a laboratory sandbox aquifer. The compared models included: (1) isotropic and anisotropic effective parameter models; (2) a heterogeneous model that faithfully represents the geological features; and (3) a heterogeneous model based on geostatistical inverse modeling. The performance of these models was assessed by quantitatively examining the results from model calibration and validation. Calibration data consisted of steady state drawdown data from eight pumping tests and validation data consisted of data from 16 separate pumping tests not used in the calibration effort. Results revealed that the geostatistical inversion approach performed the best among the approaches compared, although the geological model that faithfully represented stratigraphy came a close second. In addition, when the number of pumping tests available for inverse modeling was small, the geological modeling approach yielded more robust validation results. This suggests that better knowledge of stratigraphy obtained via geophysics or other means may contribute to improved results for HT.

  12. CH Packaging Operations Manual

    Energy Technology Data Exchange (ETDEWEB)

    Washington TRU Solutions LLC

    2005-06-13

    This procedure provides instructions for assembling the CH Packaging Drum payload assembly, Standard Waste Box (SWB) assembly, Abnormal Operations and ICV and OCV Preshipment Leakage Rate Tests on the packaging seals, using a nondestructive Helium (He) Leak Test.

  13. Dual Use Packaging Project

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA seeks down-weighted packaging compatible with microwave preparation and perhaps high hydrostatic pressure processing. New packaging must satisfy NASA's 3-year...

  14. Merganser Download Package

    Data.gov (United States)

    U.S. Environmental Protection Agency — This data download package contains an Esri 10.0 MXD, file geodatabase and copy of this FGDC metadata record. The data in this package are used in support of the...

  15. Comparative Packaging Study

    Science.gov (United States)

    Perchonok, Michele; Antonini, David

    2008-01-01

    This viewgraph presentation describes a comparative packaging study for use on long duration space missions. The topics include: 1) Purpose; 2) Deliverables; 3) Food Sample Selection; 4) Experimental Design Matrix; 5) Permeation Rate Comparison; and 6) Packaging Material Information.

  16. Directory of certificates of compliance for radioactive materials packages. Summary report of NRC approved packages

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-10-01

    This directory contains a Summary Report of NRC Approved Packages for radioactive material packages effective September 14, 1979. Purpose of this directory is to make available a convenient source of information on packagings which have been approved by the US Nuclear Regulatory Commission. To assist in identifying packaging, an index by Model Number and corresponding Certificate of Compliance number is included at the back of each volume of the directory. The Summary Report includes a listing of all users of each package design prior to the publication date of the directory.

  17. Materials for advanced packaging

    CERN Document Server

    Wong, CP

    2008-01-01

    Significant progress has been made in advanced packaging in recent years. Several new packaging techniques have been developed and new packaging materials have been introduced. This book provides a comprehensive overview of the recent developments in this industry, particularly in the areas of microelectronics, optoelectronics, digital health, and bio-medical applications. The book discusses established techniques, as well as emerging technologies, in order to provide readers with the most up-to-date developments in advanced packaging.

  18. Packaging Printing Today

    OpenAIRE

    Bolanča, Stanislav; Majnarić, Igor; Golubović, Kristijan

    2015-01-01

    Printing packaging covers today about 50% of all the printing products. Among the printing products there are printing on labels, printing on flexible packaging, printing on folding boxes, printing on the boxes of corrugated board, printing on glass packaging, synthetic and metal ones. The mentioned packaging are printed in flexo printing technique, offset printing technique, intaglio halftone process, silk – screen printing, ink ball printing, digital printing and hybrid print...

  19. A Global Remote Laboratory Experimentation Network and the Experiment Service Provider Business Model and Plans

    Directory of Open Access Journals (Sweden)

    Tor Ivar Eikaas

    2003-07-01

    Full Text Available This paper presents results from the IST KAII Trial project ReLAX - Remote LAboratory eXperimentation trial (IST 1999-20827, and contributes with a framework for a global remote laboratory experimentation network supported by a new business model. The paper presents this new Experiment Service Provider business model that aims at bringing physical experimentation back into the learning arena, where remotely operable laboratory experiments used in advanced education and training schemes are made available to a global education and training market in industry and academia. The business model is based on an approach where individual experiment owners offer remote access to their high-quality laboratory facilities to users around the world. The usage can be for research, education, on-the-job training etc. The access to these facilities is offered via an independent operating company - the Experiment Service Provider. The Experiment Service Provider offers eCommerce services like booking, access control, invoicing, dispute resolution, quality control, customer evaluation services and a unified Lab Portal.

  20. Modeling Soil Organic Carbon at Regional Scale by Combining Multi-Spectral Images with Laboratory Spectra.

    Science.gov (United States)

    Peng, Yi; Xiong, Xiong; Adhikari, Kabindra; Knadel, Maria; Grunwald, Sabine; Greve, Mogens Humlekrog

    2015-01-01

    There is a great challenge in combining soil proximal spectra and remote sensing spectra to improve the accuracy of soil organic carbon (SOC) models. This is primarily because mixing of spectral data from different sources and technologies to improve soil models is still in its infancy. The first objective of this study was to integrate information of SOC derived from visible near-infrared reflectance (Vis-NIR) spectra in the laboratory with remote sensing (RS) images to improve predictions of topsoil SOC in the Skjern river catchment, Denmark. The second objective was to improve SOC prediction results by separately modeling uplands and wetlands. A total of 328 topsoil samples were collected and analyzed for SOC. Satellite Pour l'Observation de la Terre (SPOT5), Landsat Data Continuity Mission (Landsat 8) images, laboratory Vis-NIR and other ancillary environmental data including terrain parameters and soil maps were compiled to predict topsoil SOC using Cubist regression and Bayesian kriging. The results showed that the model developed from RS data, ancillary environmental data and laboratory spectral data yielded a lower root mean square error (RMSE) (2.8%) and higher R2 (0.59) than the model developed from only RS data and ancillary environmental data (RMSE: 3.6%, R2: 0.46). Plant-available water (PAW) was the most important predictor for all the models because of its close relationship with soil organic matter content. Moreover, vegetation indices, such as the Normalized Difference Vegetation Index (NDVI) and Enhanced Vegetation Index (EVI), were very important predictors in SOC spatial models. Furthermore, the 'upland model' was able to more accurately predict SOC compared with the 'upland & wetland model'. However, the separately calibrated 'upland and wetland model' did not improve the prediction accuracy for wetland sites, since it was not possible to adequately discriminate the vegetation in the RS summer images. We conclude that laboratory Vis

  1. Central heating: package boilers

    Energy Technology Data Exchange (ETDEWEB)

    Farahan, E.

    1977-05-01

    Performance and cost data for electrical and fossil-fired package boilers currently available from manufacturers are provided. Performance characteristics investigated include: unit efficiency, rated capacity, and average expected lifetime of units. Costs are tabulated for equipment and installation of various package boilers. The information supplied in this report will simplify the process of selecting package boilers required for industrial, commercial, and residential applications.

  2. Display system software for the integration of an ADAGE 3000 programmable display generator into the solid modeling package C.A.D. software

    Science.gov (United States)

    Montoya, R. J.; Lane, H. H., Jr.

    1986-01-01

    A software system that integrates an ADAGE 3000 Programmable Display Generator into a C.A.D. software package known as the Solid Modeling Program is described. The Solid Modeling Program (SMP) is an interactive program that is used to model complex solid object through the composition of primitive geomeentities. In addition, SMP provides extensive facilities for model editing and display. The ADAGE 3000 Programmable Display Generator (PDG) is a color, raster scan, programmable display generator with a 32-bit bit-slice, bipolar microprocessor (BPS). The modularity of the system architecture and the width and speed of the system bus allow for additional co-processors in the system. These co-processors combine to provide efficient operations on and rendering of graphics entities. The resulting software system takes advantage of the graphics capabilities of the PDG in the operation of SMP by distributing its processing modules between the host and the PDG. Initially, the target host computer was a PRIME 850, which was later substituted with a VAX-11/785. Two versions of the software system were developed, a phase 1 and a phase 2. In phase 1, the ADAGE 3000 is used as a frame buffer. In phase II, SMP was functionally partitioned and some of its functions were implemented in the ADAGE 3000 by means of ADAGE's SOLID 3000 software package.

  3. Model-Based Reasoning in the Upper-Division Physics Laboratory: Framework and Initial Results

    CERN Document Server

    Zwickl, Benjamin M; Finkelstein, Noah; Lewandowski, H J

    2014-01-01

    Constructing and using models are core scientific practices that have gained significant attention within K-12 and higher education. Although modeling is a broadly applicable process, within physics education, it has been preferentially applied to the iterative development of broadly applicable principles (e.g., Newton's laws of motion in introductory mechanics). We review and extend existing frameworks on modeling to develop a new framework that more naturally describes model-based reasoning in upper-division physics labs. A significant feature of the new framework is that measurement tools (in addition to the physical system being studied) are subjected to the process of modeling. Think-aloud interviews were used to document examples of model-based reasoning in the laboratory and refine the modeling framework. The interviews showed how students productively applied similar facets of modeling to the physical system and measurement tools: construction, prediction, interpretation of data, identification of mod...

  4. MODFLOW-2000, the U.S. Geological Survey modular ground-water model -- Documentation of the Model-Layer Variable-Direction Horizontal Anisotropy (LVDA) capability of the Hydrogeologic-Unit Flow (HUF) package

    Science.gov (United States)

    Anderman, Evan R.; Kipp, K.L.; Hill, Mary C.; Valstar, Johan; Neupauer, R.M.

    2002-01-01

    This report documents the model-layer variable-direction horizontal anisotropy (LVDA) capability of the Hydrogeologic-Unit Flow (HUF) Package of MODFLOW-2000. The LVDA capability allows the principal directions of horizontal anisotropy to be different than the model-grid row and column directions, and for the directions to vary on a cell-by-cell basis within model layers. The HUF Package calculates effective hydraulic properties for model grid cells based on hydraulic properties of hydrogeologic units with thicknesses defined independently of the model layers. These hydraulic properties include, among other characteristics, hydraulic conductivity and a horizontal anisotropy ratio. Using the LVDA capability, horizontal anisotropy direction is defined for model grid cells within which one or more hydrogeologic units may occur. For each grid cell, the HUF Package calculates the effective horizontal hydraulic conductivity along the primary direction of anisotropy using the hydrogeologic-unit hydraulic conductivities, and calculates the effective horizontal hydraulic conductivity along the orthogonal anisotropy direction using the effective primary direction hydraulic conductivities and horizontal anisotropy ratios. The direction assigned to the model layer effective primary hydraulic conductivity is specified using a new data set defined by the LVDA capability, when active, to calculate coefficients needed to solve the ground-water flow equation. Use of the LVDA capability is illustrated in four simulation examples, which also serve to verify hydraulic heads, advective-travel paths, and sensitivities calculated using the LVDA capability. This version of the LVDA capability defines variable-direction horizontal anisotropy using model layers, not the hydrogeologic units defined by the HUF Package. This difference needs to be taken into account when designing model layers and hydrogeologic units to produce simulations that accurately represent a given field problem. This

  5. Vadose Zone Hydrogeology Data Package for Hanford Assessments

    Energy Technology Data Exchange (ETDEWEB)

    Last, George V.; Freeman, Eugene J.; Cantrell, Kirk J.; Fayer, Michael J.; Gee, Glendon W.; Nichols, William E.; Bjornstad, Bruce N.; Horton, Duane G.

    2006-06-01

    This data package documents the technical basis for selecting physical and geochemical parameters and input values that will be used in vadose zone modeling for Hanford assessments. This work was originally conducted as part of the Characterization of Systems Task of the Groundwater Remediation Project managed by Fluor Hanford, Inc., Richland, Washington, and revised as part of the Characterization of Systems Project managed by the Pacific Northwest National Laboratory (PNNL) for the U.S. Department of Energy, Richland Operations Office (DOE-RL). This data package describes the geologic framework, the physical, hydrologic, and contaminant transport properties of the geologic materials, and deep drainage (i.e., recharge) estimates, and builds on the general framework developed for the initial assessment conducted using the System Assessment Capability (SAC) (Bryce et al. 2002). The general approach for this work was to update and provide incremental improvements over the previous SAC data package completed in 2001. As with the previous SAC data package, much of the data and interpreted information were extracted from existing documents and databases. Every attempt was made to provide traceability to the original source(s) of the data or interpretations.

  6. Simulation and Training Package on Corex Process

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    A software package has been developed for simulation on the Corex process. The simulation and training package on the process of shaft furnace using Corex off gas were introduced. The package consists of three main modules, namely the numerical simulation, the system modeling and optimization, and the training module, which are integrated with graphical interfaces. In addition, the equipment starting and stopping operation and typical trouble-shooting were also included in the package, whereby a practical environment can be established for training of operation and management stuff.

  7. Active Packaging Coatings

    Directory of Open Access Journals (Sweden)

    Luis J. Bastarrachea

    2015-11-01

    Full Text Available Active food packaging involves the packaging of foods with materials that provide an enhanced functionality, such as antimicrobial, antioxidant or biocatalytic functions. This can be achieved through the incorporation of active compounds into the matrix of the commonly used packaging materials, or by the application of coatings with the corresponding functionality through surface modification. The latter option offers the advantage of preserving the packaging materials’ bulk properties nearly intact. Herein, different coating technologies like embedding for controlled release, immobilization, layer-by-layer deposition, and photografting are explained and their potential application for active food packaging is explored and discussed.

  8. PBM: a software package to create, display and manipulate interactively models of small molecules and proteins on IBM-compatible PCs.

    Science.gov (United States)

    Perrakis, A; Constantinides, C; Athanasiades, A; Hamodrakas, S J

    1995-04-01

    The PBM package was developed to create, display and conveniently manipulate protein and small molecule structures on IBM-compatible microcomputers. It consists of four modules: CREATE, SPHERE, RIBBON and CONVERT. CREATE includes commands to create or alter ('mutate') the primary and subsequently the tertiary structure of a given peptide or protein by defining phi and psi angles of residues at will, options to add, delete or alter atoms in a structure, utilities to choose easily between the most common rotamers of amino acid residue sidechains and options to analyse in various ways a protein conformation. SPHERE provides for an interactive manipulation of structures containing up to 2700 atoms which can belong up to six different molecules. All manipulations can be made with the use of an ordinary mouse, by choosing from a variety of pull-down menus. Three types of models can be implemented to display molecules on the computer screen or the plotter: skeletal, solid space-filling and wireframe space-filling models. RIBBON creates ribbon models of proteins and allows for a limited variety of interactive manipulations. CONVERT is a file converter, which is capable of converting files of atom coordinates of literally any format to Brookhaven Data Bank format files. The package produces very good results for protein molecules of reasonable sizes, both in terms of graphics quality and speed of operations, on an 80486 IBM PC-compatible machine equipped with a 1 MByte VGA display card and a colour VGA monitor, which is a recommended configuration.

  9. Active vibration control with model correction on a flexible laboratory grid structure

    Science.gov (United States)

    Schamel, George C., II; Haftka, Raphael T.

    1991-01-01

    This paper presents experimental and computational comparisons of three active damping control laws applied to a complex laboratory structure. Two reduced structural models were used with one model being corrected on the basis of measured mode shapes and frequencies. Three control laws were investigated, a time-invariant linear quadratic regulator with state estimation and two direct rate feedback control laws. Experimental results for all designs were obtained with digital implementation. It was found that model correction improved the agreement between analytical and experimental results. The best agreement was obtained with the simplest direct rate feedback control.

  10. Kinetics Modeling of Hazelnut Quality Change under Nitrogen Packaging%充氮包装下榛子品质变化的动力学建模

    Institute of Scientific and Technical Information of China (English)

    王鹤腾; 董静

    2012-01-01

    The effect of packaging method on hazelnut quality was discussed. The results showed that nitrogen packaging has the best preservative effects. Kinetic models of peroxide value and acid value at different storage time and temperatures were established to predict and control the quality and shelf life of hazelnut during storage. The results showed that the peroxide value and acid value of hazelnut increases with storage time and storage temperature ; however, they increase slower because of good preservative performance of nitrogen packaging; the acid value and peroxide value has high fitting precision with the first order chemical reaction model and the Arrhenius equation.%探索了不同包装方式对榛子品质变化的影响,结果表明充氮包装保鲜效果最好。建立了充氮包装下酸价、过氧化值随贮藏温度和时间变化的动力学模型,以控制榛子在贮藏过程中的品质和货架期。结果表明,随着贮藏时间的延长和贮藏温度的升高,榛子的酸价和过氧化值不断增加,普通包装增加最快,充氮包装由于良好的保鲜性能而增长较慢。酸价、过氧化值对一级化学反应模型和Arrhenius方程具有很高的拟合精度。

  11. Ultrasound data for laboratory calibration of an analytical model to calculate crack depth on asphalt pavements

    Directory of Open Access Journals (Sweden)

    Miguel A. Franesqui

    2017-08-01

    Full Text Available This article outlines the ultrasound data employed to calibrate in the laboratory an analytical model that permits the calculation of the depth of partial-depth surface-initiated cracks on bituminous pavements using this non-destructive technique. This initial calibration is required so that the model provides sufficient precision during practical application. The ultrasonic pulse transit times were measured on beam samples of different asphalt mixtures (semi-dense asphalt concrete AC-S; asphalt concrete for very thin layers BBTM; and porous asphalt PA. The cracks on the laboratory samples were simulated by means of notches of variable depths. With the data of ultrasound transmission time ratios, curve-fittings were carried out on the analytical model, thus determining the regression parameters and their statistical dispersion. The calibrated models obtained from laboratory datasets were subsequently applied to auscultate the evolution of the crack depth after microwaves exposure in the research article entitled “Top-down cracking self-healing of asphalt pavements with steel filler from industrial waste applying microwaves” (Franesqui et al., 2017 [1].

  12. Ultrasound data for laboratory calibration of an analytical model to calculate crack depth on asphalt pavements.

    Science.gov (United States)

    Franesqui, Miguel A; Yepes, Jorge; García-González, Cándida

    2017-08-01

    This article outlines the ultrasound data employed to calibrate in the laboratory an analytical model that permits the calculation of the depth of partial-depth surface-initiated cracks on bituminous pavements using this non-destructive technique. This initial calibration is required so that the model provides sufficient precision during practical application. The ultrasonic pulse transit times were measured on beam samples of different asphalt mixtures (semi-dense asphalt concrete AC-S; asphalt concrete for very thin layers BBTM; and porous asphalt PA). The cracks on the laboratory samples were simulated by means of notches of variable depths. With the data of ultrasound transmission time ratios, curve-fittings were carried out on the analytical model, thus determining the regression parameters and their statistical dispersion. The calibrated models obtained from laboratory datasets were subsequently applied to auscultate the evolution of the crack depth after microwaves exposure in the research article entitled "Top-down cracking self-healing of asphalt pavements with steel filler from industrial waste applying microwaves" (Franesqui et al., 2017) [1].

  13. Edible packaging materials.

    Science.gov (United States)

    Janjarasskul, Theeranun; Krochta, John M

    2010-01-01

    Research groups and the food and pharmaceutical industries recognize edible packaging as a useful alternative or addition to conventional packaging to reduce waste and to create novel applications for improving product stability, quality, safety, variety, and convenience for consumers. Recent studies have explored the ability of biopolymer-based food packaging materials to carry and control-release active compounds. As diverse edible packaging materials derived from various by-products or waste from food industry are being developed, the dry thermoplastic process is advancing rapidly as a feasible commercial edible packaging manufacturing process. The employment of nanocomposite concepts to edible packaging materials promises to improve barrier and mechanical properties and facilitate effective incorporation of bioactive ingredients and other designed functions. In addition to the need for a more fundamental understanding to enable design to desired specifications, edible packaging has to overcome challenges such as regulatory requirements, consumer acceptance, and scaling-up research concepts to commercial applications.

  14. PNNL Technical Support to The Implementation of EMTA and EMTA-NLA Models in Autodesk® Moldflow® Packages

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, Ba Nghiep; Wang, Jin

    2012-12-01

    Under the Predictive Engineering effort, PNNL developed linear and nonlinear property prediction models for long-fiber thermoplastics (LFTs). These models were implemented in PNNL’s EMTA and EMTA-NLA codes. While EMTA is a standalone software for the computation of the composites thermoelastic properties, EMTA-NLA presents a series of nonlinear models implemented in ABAQUS® via user subroutines for structural analyses. In all these models, it is assumed that the fibers are linear elastic while the matrix material can exhibit a linear or typical nonlinear behavior depending on the loading prescribed to the composite. The key idea is to model the constitutive behavior of the matrix material and then to use an Eshelby-Mori-Tanaka approach (EMTA) combined with numerical techniques for fiber length and orientation distributions to determine the behavior of the as-formed composite. The basic property prediction models of EMTA and EMTA-NLA have been subject for implementation in the Autodesk® Moldflow® software packages. These models are the elastic stiffness model accounting for fiber length and orientation distributions, the fiber/matrix interface debonding model, and the elastic-plastic models. The PNNL elastic-plastic models for LFTs describes the composite nonlinear stress-strain response up to failure by an elastic-plastic formulation associated with either a micromechanical criterion to predict failure or a continuum damage mechanics formulation coupling damage to plasticity. All the models account for fiber length and orientation distributions as well as fiber/matrix debonding that can occur at any stage of loading. In an effort to transfer the technologies developed under the Predictive Engineering project to the American automotive and plastics industries, PNNL has obtained the approval of the DOE Office of Vehicle Technologies to provide Autodesk, Inc. with the technical support for the implementation of the basic property prediction models of EMTA and

  15. Microbial dynamics in a High Arctic glacier forefield: a combined field, laboratory, and modelling approach

    Science.gov (United States)

    Bradley, James A.; Arndt, Sandra; Šabacká, Marie; Benning, Liane G.; Barker, Gary L.; Blacker, Joshua J.; Yallop, Marian L.; Wright, Katherine E.; Bellas, Christopher M.; Telling, Jonathan; Tranter, Martyn; Anesio, Alexandre M.

    2016-10-01

    Modelling the development of soils in glacier forefields is necessary in order to assess how microbial and geochemical processes interact and shape soil development in response to glacier retreat. Furthermore, such models can help us predict microbial growth and the fate of Arctic soils in an increasingly ice-free future. Here, for the first time, we combined field sampling with laboratory analyses and numerical modelling to investigate microbial community dynamics in oligotrophic proglacial soils in Svalbard. We measured low bacterial growth rates and growth efficiencies (relative to estimates from Alpine glacier forefields) and high sensitivity of bacterial growth rates to soil temperature (relative to temperate soils). We used these laboratory measurements to inform parameter values in a new numerical model and significantly refined predictions of microbial and biogeochemical dynamics of soil development over a period of roughly 120 years. The model predicted the observed accumulation of autotrophic and heterotrophic biomass. Genomic data indicated that initial microbial communities were dominated by bacteria derived from the glacial environment, whereas older soils hosted a mixed community of autotrophic and heterotrophic bacteria. This finding was simulated by the numerical model, which showed that active microbial communities play key roles in fixing and recycling carbon and nutrients. We also demonstrated the role of allochthonous carbon and microbial necromass in sustaining a pool of organic material, despite high heterotrophic activity in older soils. This combined field, laboratory, and modelling approach demonstrates the value of integrated model-data studies to understand and quantify the functioning of the microbial community in an emerging High Arctic soil ecosystem.

  16. Optimization of Train Trip Package Operation Scheme

    Directory of Open Access Journals (Sweden)

    Lu Tong

    2015-01-01

    Full Text Available Train trip package transportation is an advanced form of railway freight transportation, realized by a specialized train which has fixed stations, fixed time, and fixed path. Train trip package transportation has lots of advantages, such as large volume, long distance, high speed, simple forms of organization, and high margin, so it has become the main way of railway freight transportation. This paper firstly analyzes the related factors of train trip package transportation from its organizational forms and characteristics. Then an optimization model for train trip package transportation is established to provide optimum operation schemes. The proposed model is solved by the genetic algorithm. At last, the paper tests the model on the basis of the data of 8 regions. The results show that the proposed method is feasible for solving operation scheme issues of train trip package.

  17. International on Workshop Advances in Laboratory Testing & Modelling of Soils and Shales

    CERN Document Server

    Laloui, Lyesse

    2017-01-01

    In this spirit, the ATMSS International Workshop “Advances in Laboratory Testing & Modelling of Soils and Shales” (Villars-sur-Ollon, Switzerland; 18-20 January 2017) has been organized to promote the exchange of ideas, experience and state of the art among major experts active in the field of experimental testing and modelling of soils and shales. The Workshop has been organized under the auspices of the Technical Committees TC-101 “Laboratory Testing”, TC-106 “Unsaturated Soils” and TC-308 “Energy Geotechnics” of the International Society of Soil Mechanics and Geotechnical Engineering. This volume contains the invited keynote and feature lectures, as well as the papers that have been presented at the Workshop. The topics of the lectures and papers cover a wide range of theoretical and experimental research, including unsaturated behaviour of soils and shales, multiphysical testing of geomaterials, hydro–mechanical behaviour of shales and stiff clays, the geomechanical behaviour of the ...

  18. Iceberg capsize hydrodynamics: a comparison of laboratory experiments and numerical modeling

    Science.gov (United States)

    Burton, J. C.; Cathles, L. M.; Correa-Legisos, S.; Ellowitz, J.; Darnell, K.; Zhang, W. W.; MacAyeal, D. R.

    2013-12-01

    Large icebergs are often observed to capsize in open water near fjords. During capsize, large amounts of gravitational potential energy are released which can lead to coastal tsunamis, mixing of the water column, and possibly lead to further calving at the glacier terminus. This process is rarely studied; in nature the scale and irregular timing of the events makes observations exceedingly difficult. Here we compare laboratory experiments and numerical modeling of the capsize process to better understand the coupling of the hydrodynamic forces to the solid iceberg. Although the characteristic Reynolds number is much lower for both the laboratory model and the numerical simulations, the comparison provides a starting point to quantify and identify generic features that can be estimated in the field, such as hydrodynamic pressure, water flow velocities, vertical mixing, and elastic stresses on the iceberg itself, which could lead to fracture.

  19. MODFLOW-2000, the U.S. Geological Survey modular ground-water model : user guide to the LMT6 package, the linkage with MT3DMS for multi-species mass transport modeling

    Science.gov (United States)

    Zheng, Chunmiao; Hill, Mary Catherine; Hsieh, Paul A.

    2001-01-01

    MODFLOW-2000, the newest version of MODFLOW, is a computer program that numerically solves the three-dimensional ground-water flow equation for a porous medium using a finite-difference method. MT3DMS, the successor to MT3D, is a computer program for modeling multi-species solute transport in three-dimensional ground-water systems using multiple solution techniques, including the finite-difference method, the method of characteristics (MOC), and the total-variation-diminishing (TVD) method. This report documents a new version of the Link-MT3DMS Package, which enables MODFLOW-2000 to produce the information needed by MT3DMS, and also discusses new visualization software for MT3DMS. Unlike the Link-MT3D Packages that coordinated previous versions of MODFLOW and MT3D, the new Link-MT3DMS Package requires an input file that, among other things, provides enhanced support for additional MODFLOW sink/source packages and allows list-directed (free) format for the flow model produced flow-transport link file. The report contains four parts: (a) documentation of the Link-MT3DMS Package Version 6 for MODFLOW-2000; (b) discussion of several issues related to simulation setup and input data preparation for running MT3DMS with MODFLOW-2000; (c) description of two test example problems, with comparison to results obtained using another MODFLOW-based transport program; and (d) overview of post-simulation visualization and animation using the U.S. Geological Survey?s Model Viewer.

  20. The extended Beer-Lambert theory for ray tracing modeling of LED chip-scaled packaging application with multiple luminescence materials

    Science.gov (United States)

    Yuan, Cadmus C. A.

    2015-12-01

    Optical ray tracing modeling applied Beer-Lambert method in the single luminescence material system to model the white light pattern from blue LED light source. This paper extends such algorithm to a mixed multiple luminescence material system by introducing the equivalent excitation and emission spectrum of individual luminescence materials. The quantum efficiency numbers of individual material and self-absorption of the multiple luminescence material system are considered as well. By this combination, researchers are able to model the luminescence characteristics of LED chip-scaled packaging (CSP), which provides simple process steps and the freedom of the luminescence material geometrical dimension. The method will be first validated by the experimental results. Afterward, a further parametric investigation has been then conducted.

  1. IMAP refid="FN1">©©Copyright Sandia Corporation and Lawrence Livermore National Laboratories, April 1993.: a complete Ion Micro-Analysis Package for the nuclear microprobe

    Science.gov (United States)

    Antolak, A. J.; Bench, G. S.; Morse, D. H.

    1994-03-01

    Microprobe techniques using scanned, focused MeV ions are routinely used in Livermore for materials characterization. Comprehensive data analysis with these techniques is accomplished with the computer software package IMAP, for Ion Micro-Analysis Package. IMAP consists of a set of command language procedures for data processing and quantitative spectral analysis. Deconvolution of the data is achieved by spawning sub-processes within IMAP which execute analysis codes for each specific microprobe technique. IMAP is structured to rapidly analyze individual spectra or multi-dimensional data blocks which classify individual events by the two scanning dimensions, the energy of the detected radiation and, when necessary, one sample rotation dimension. Several examples are presented to demonstrate the utility of the package.

  2. 基于连锁超市的包装废弃物回收模型%Recycling Model of Waste Packaging Materials for Chain Supermarkets

    Institute of Scientific and Technical Information of China (English)

    黄勇; 邱丽艳

    2013-01-01

    阐述了包装废弃物回收的意义,基于资源整合与共享的理论思想,提出连锁超市的回收模式,即基于连锁超市的配送体系,在连锁超市合理选址的基础上,依超市建立回收站点,集中回收可再利用的包装;充分利用配送中心的网络资源,建立以达到降低物流成本,实现资源再利用为目的的模型.最后用模糊综合评价法对其进行了评价.%In this paper, we introduced the significance of the recycling of waste packaging materials and on the basis of the ideas of resource integration and sharing, proposed the recycling model of the chain supermarkets, which, on the basis of the reasonable location of the supermarkets, recycled reusable packaging materials in a centralized way and made full use of the network resource of the distribution centers to reduce logistics cost and realize resource reclamation. At the end, we evaluated the model using fuzzy comprehensive evaluation method.

  3. Hybrid-structure atomic models for HED laboratory plasma diagnostics and simulations

    Science.gov (United States)

    Hansen, Stephanie

    2010-03-01

    While theoretical atomic physics calculations are well developed for isolated atoms and have been thoroughly benchmarked against low-density laboratory sources such as electron beam ion traps and tokamak plasmas, the high energy density (HED) regime offers significant challenges for atomic physics and spectroscopic modeling. High plasma densities lead to collective effects such as continuum lowering, line broadening, and significant populations in multiply excited atomic states. These effects change the plasma equation of state and the character of emission and absorption spectra and must be accounted for in order to accurately simulate radiative transfer in and apply spectroscopic diagnostics to HED plasmas. Modeling complex mid- and high-Z ions in the HED regime is a particular challenge because exponential growth in accessible configuration space overwhelms the reduction of the Rydberg levels through continuum lowering. This talk will discuss one approach to generating a tractable spectroscopic-quality atomic kinetics model and describe its application to HED laboratory plasmas produced on Sandia's Z facility. [4pt] Sandia is a multi-program laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the United States Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000.

  4. Packaging and transportation manual. Chapter on the packaging and transportation of hazardous and radioactive waste

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The purpose of this chapter is to outline the requirements that Los Alamos National Laboratory employees and contractors must follow when they package and ship hazardous and radioactive waste. This chapter is applied to on-site, intra-Laboratory, and off-site transportation of hazardous and radioactive waste. The chapter contains sections on definitions, responsibilities, written procedures, authorized packaging, quality assurance, documentation for waste shipments, loading and tiedown of waste shipments, on-site routing, packaging and transportation assessment and oversight program, nonconformance reporting, training of personnel, emergency response information, and incident and occurrence reporting. Appendices provide additional detail, references, and guidance on packaging for hazardous and radioactive waste, and guidance for the on-site transport of these wastes.

  5. 黄鹤楼品牌个性化卷烟包装形态的造型设计%Modeling Design of Packaging form of Huanghelou Personalized Cigarette

    Institute of Scientific and Technical Information of China (English)

    孙明海; 于琳

    2012-01-01

    通过对黄鹤楼卷烟品牌的个性化包装造型的分析,总结出个性化烟包形态造型的设计法则,并阐述了个性化烟包设计对于消费者产生的心理效应,以此着手设计个性化烟包以达到吸引消费者,促进销售,并为品牌带来广阔市场的设计目的。%Through the analysis of the personalized packaging modeling of Huanghelou cigaretted,it summed up the design rules of personalized cigarette packaging,expounded the psychological effects of personalized cigarette packaging design for consumers,in order to design personalized cigarette packaging to attract consumers,promote the sale and bring the vast market for the brand.

  6. Incorporating learning goals about modeling into an upper-division physics laboratory experiment

    Science.gov (United States)

    Zwickl, Benjamin M.; Finkelstein, Noah; Lewandowski, H. J.

    2014-09-01

    Implementing a laboratory activity involves a complex interplay among learning goals, available resources, feedback about the existing course, best practices for teaching, and an overall philosophy about teaching labs. Building on our previous work, which described a process of transforming an entire lab course, we now turn our attention to how an individual lab activity on the polarization of light was redesigned to include a renewed emphasis on one broad learning goal: modeling. By using this common optics lab as a concrete case study of a broadly applicable approach, we highlight many aspects of the activity development and show how modeling is used to integrate sophisticated conceptual and quantitative reasoning into the experimental process through the various aspects of modeling: constructing models, making predictions, interpreting data, comparing measurements with predictions, and refining models. One significant outcome is a natural way to integrate an analysis and discussion of systematic error into a lab activity.

  7. Survey of biomedical and environental data bases, models, and integrated computer systems at Argonne National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Murarka, I.P.; Bodeau, D.J.; Scott, J.M.; Huebner, R.H.

    1978-08-01

    This document contains an inventory (index) of information resources pertaining to biomedical and environmental projects at Argonne National Laboratory--the information resources include a data base, model, or integrated computer system. Entries are categorized as models, numeric data bases, bibliographic data bases, or integrated hardware/software systems. Descriptions of the Information Coordination Focal Point (ICFP) program, the system for compiling this inventory, and the plans for continuing and expanding it are given, and suggestions for utilizing the services of the ICFP are outlined.

  8. Comparison of truncated shell model calculations in the laboratory and intrinsic systems

    Energy Technology Data Exchange (ETDEWEB)

    Catara, F.; Insolia, A.; Sambataro, M.; Maglione, E.; Vitturi, A.

    1985-08-01

    We perform, in the case of particles moving in a single-j level, shell model calculations in which the angular momentum of the individual pairs is restricted to a maximum value. The comparison with the full calculation shows the need for including at least the G pairs in the model space in order to reproduce the correct moments of inertia and transition rates of the different rotational bands. We also show that a level scheme very close to that obtained in the laboratory system can be alternatively obtained by angular momentum projection starting from intrinsic states evaluated in the intrinsic frame.

  9. Description of a digital computer simulation of an Annular Momentum Control Device (AMCD) laboratory test model

    Science.gov (United States)

    Woolley, C. T.; Groom, N. J.

    1981-01-01

    A description of a digital computer simulation of an Annular Momentum Control Device (AMCD) laboratory model is presented. The AMCD is a momentum exchange device which is under development as an advanced control effector for spacecraft attitude control systems. The digital computer simulation of this device incorporates the following models: six degree of freedom rigid body dynamics; rim warp; controller dynamics; nonlinear distributed element axial bearings; as well as power driver and power supply current limits. An annotated FORTRAN IV source code listing of the computer program is included.

  10. Packaging for Sustainability

    CERN Document Server

    Lewis, Helen; Fitzpatrick, Leanne

    2012-01-01

    The packaging industry is under pressure from regulators, customers and other stakeholders to improve packaging’s sustainability by reducing its environmental and societal impacts. This is a considerable challenge because of the complex interactions between products and their packaging, and the many roles that packaging plays in the supply chain. Packaging for Sustainability is a concise and readable handbook for practitioners who are trying to implement sustainability strategies for packaging. Industry case studies are used throughout the book to illustrate possible applications and scenarios. Packaging for Sustainability draws on the expertise of researchers and industry practitioners to provide information on business benefits, environmental issues and priorities, environmental evaluation tools, design for environment, marketing strategies, and challenges for the future.

  11. Mapping mantle flow during retreating subduction: Laboratory models analyzed by feature tracking

    Science.gov (United States)

    Funiciello, F.; Moroni, M.; Piromallo, C.; Faccenna, C.; Cenedese, A.; Bui, H. A.

    2006-03-01

    Three-dimensional dynamically consistent laboratory models are carried out to model the large-scale mantle circulation induced by subduction of a laterally migrating slab. A laboratory analogue of a slab-upper mantle system is set up with two linearly viscous layers of silicone putty and glucose syrup in a tank. The circulation pattern is continuously monitored and quantitatively estimated using a feature tracking image analysis technique. The effects of plate width and mantle viscosity/density on mantle circulation are systematically considered. The experiments show that rollback subduction generates a complex three-dimensional time-dependent mantle circulation pattern characterized by the presence of two distinct components: the poloidal and the toroidal circulation. The poloidal component is the answer to the viscous coupling between the slab motion and the mantle, while the toroidal one is produced by lateral slab migration. Spatial and temporal features of mantle circulation are carefully analyzed. These models show that (1) poloidal and toroidal mantle circulation are both active since the beginning of the subduction process, (2) mantle circulation is intermittent, (3) plate width affects the velocity and the dimension of subduction induced mantle circulation area, and (4) mantle flow in subduction zones cannot be correctly described by models assuming a two-dimensional steady state process. We show that the intermittent toroidal component of mantle circulation, missed in those models, plays a crucial role in modifying the geometry and the efficiency of the poloidal component.

  12. Cross-flow turbines: progress report on physical and numerical model studies at large laboratory scale

    Science.gov (United States)

    Wosnik, Martin; Bachant, Peter

    2016-11-01

    Cross-flow turbines show potential in marine hydrokinetic (MHK) applications. A research focus is on accurately predicting device performance and wake evolution to improve turbine array layouts for maximizing overall power output, i.e., minimizing wake interference, or taking advantage of constructive wake interaction. Experiments were carried with large laboratory-scale cross-flow turbines D O (1 m) using a turbine test bed in a large cross-section tow tank, designed to achieve sufficiently high Reynolds numbers for the results to be Reynolds number independent with respect to turbine performance and wake statistics, such that they can be reliably extrapolated to full scale and used for model validation. Several turbines of varying solidity were employed, including the UNH Reference Vertical Axis Turbine (RVAT) and a 1:6 scale model of the DOE-Sandia Reference Model 2 (RM2) turbine. To improve parameterization in array simulations, an actuator line model (ALM) was developed to provide a computationally feasible method for simulating full turbine arrays inside Navier-Stokes models. Results are presented for the simulation of performance and wake dynamics of cross-flow turbines and compared with experiments and body-fitted mesh, blade-resolving CFD. Supported by NSF-CBET Grant 1150797, Sandia National Laboratories.

  13. Cryosphere Science Outreach using the Ice Sheet System Model and a Virtual Ice Sheet Laboratory

    Science.gov (United States)

    Cheng, D. L. C.; Halkides, D. J.; Larour, E. Y.

    2015-12-01

    Understanding the role of Cryosphere Science within the larger context of Sea Level Rise is both a technical and educational challenge that needs to be addressed if the public at large is to trulyunderstand the implications and consequences of Climate Change. Within this context, we propose a new approach in which scientific tools are used directly inside a mobile/website platform geared towards Education/Outreach. Here, we apply this approach by using the Ice Sheet System Model, a state of the art Cryosphere model developed at NASA, and integrated within a Virtual Ice Sheet Laboratory, with the goal is to outreach Cryospherescience to K-12 and College level students. The approach mixes laboratory experiments, interactive classes/lessons on a website, and a simplified interface to a full-fledged instance of ISSM to validate the classes/lessons. This novel approach leverages new insights from the Outreach/Educational community and the interest of new generations in web based technologies and simulation tools, all of it delivered in a seamlessly integrated web platform. This work was performed at the California Institute of Technology's Jet Propulsion Laboratory undera contract with the National Aeronautics and Space Administration's Cryosphere Science Program.

  14. Outreach/education interface for Cryosphere models using the Virtual Ice Sheet Laboratory

    Science.gov (United States)

    Larour, E. Y.; Halkides, D. J.; Romero, V.; Cheng, D. L.; Perez, G.

    2014-12-01

    In the past decade, great strides have been made in the development of models capable of projecting the future evolution of glaciers and the polar ice sheets in a changing climate. These models are now capable of replicating some of the trends apparent in satellite observations. However, because this field is just now maturing, very few efforts have been dedicated to adapting these capabilities to education. Technologies that have been used in outreach efforts in Atmospheric and Oceanic sciences still have not been extended to Cryospheric Science. We present a cutting-edge, technologically driven virtual laboratory, geared towards outreach and k-12 education, dedicated to the polar ice sheets on Antarctica and Greenland, and their role as major contributors to sea level rise in coming decades. VISL (Virtual Ice Sheet Laboratory) relies on state-of-the art Web GL rendering of polar ice sheets, Android/iPhone and web portability using Javascript, as well as C++ simulations (back-end) based on the Ice Sheet System Model, the NASA model for simulating the evolution of polar ice sheets. Using VISL, educators and students can have an immersive experience into the world of polar ice sheets, while at the same exercising the capabilities of a state-of-the-art climate model, all of it embedded into an education experience that follows the new STEM standards for education.This work was performed at the California Institute of Technology's Jet Propulsion Laboratory under a contract with the National Aeronautics and Space Administration's Cryosphere Science Program.

  15. Heat Pump Water Heater Technology Assessment Based on Laboratory Research and Energy Simulation Models: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Hudon, K.; Sparn, B.; Christensen, D.; Maguire, J.

    2012-02-01

    This paper explores the laboratory performance of five integrated Heat Pump Water Heaters (HPWHs) across a wide range of operating conditions representative of US climate regions. Laboratory results demonstrate the efficiency of this technology under most of the conditions tested and show that differences in control schemes and design features impact the performance of the individual units. These results were used to understand current model limitations, and then to bracket the energy savings potential for HPWH technology in various US climate regions. Simulation results show that HPWHs are expected to provide significant energy savings in many climate zones when compared to other types of water heaters (up to 64%, including impact on HVAC systems).

  16. The Role of Heterogeneous Chemistry of Volatile ORganic Compounds: A Modeling and Laboratory Study

    Energy Technology Data Exchange (ETDEWEB)

    Gregory R. Carmichael; Vicki H. Grassian

    2007-03-01

    Overview The outputs of this research have been reported annually via the RIMS system. This report serves as an update and final report. The focus of our DOE BES funded project is on the importance of heterogeneous reactions in the troposphere. The primary objectives of our study were to: (i) Evaluate the extent to which heterogeneous chemistry affects the photochemical oxidant cycle, particularly, sources and sinks of tropospheric ozone; and (ii) Conduct laboratory studies on heterogeneous reactions involving NOy, O3 and VOCs on aerosol surfaces. These objectives were pursued through a multidisciplinary approach that combines modeling and laboratory components as discussed in more detail below. In addition, in response to the reconfiguring of the Atmospheric Science Program to focus on aerosol radiative forcing of climate, we also began to investigate the radiative properties of atmospheric aerosol.

  17. Laboratory strains of Escherichia coli: model citizens or deceitful delinquents growing old disgracefully?

    Science.gov (United States)

    Hobman, Jon L; Penn, Charles W; Pallen, Mark J

    2007-05-01

    Escherichia coli stands unchallenged as biology's premier model organism. However, we propose, equipped with insights from the post-genomic era, a contrary view: that microbiology's chief idol has feet of clay. E. coli laboratory strains, particularly E. coli K-12, are far from model citizens, but instead degenerate and deceitful delinquents growing old disgracefully in our scientific institutions. E. coli K-12 is neither archetype nor ancestor. In addition, it has a far from optimal provenance for a model organism, with strong grounds for believing that current versions of the strain are quite distinct from any original wild-type free-living ancestor. In addition, it is usually studied under conditions far removed from its natural habitats and in ignorance of the selective pressures that have shaped its evolution. Fortunately, a flood of information from high-throughput genome sequencing, together with a new 'eco-evo' view of this model organism, promises to help put K-12 better into context.

  18. The seismic cycle at subduction thrusts: 2. Dynamic implications of geodynamic simulations validated with laboratory models

    KAUST Repository

    van Dinther, Y.

    2013-04-01

    The physics governing the seismic cycle at seismically active subduction zones remains poorly understood due to restricted direct observations in time and space. To investigate subduction zone dynamics and associated interplate seismicity, we validate a continuum, visco-elasto-plastic numerical model with a new laboratory approach (Paper 1). The analogous laboratory setup includes a visco-elastic gelatin wedge underthrusted by a rigid plate with defined velocity-weakening and -strengthening regions. Our geodynamic simulation approach includes velocity-weakening friction to spontaneously generate a series of fast frictional instabilities that correspond to analog earthquakes. A match between numerical and laboratory source parameters is obtained when velocity-strengthening is applied in the aseismic regions to stabilize the rupture. Spontaneous evolution of absolute stresses leads to nucleation by coalescence of neighboring patches, mainly occurring at evolving asperities near the seismogenic zone limits. Consequently, a crack-, or occasionally even pulse-like, rupture propagates toward the opposite side of the seismogenic zone by increasing stresses ahead of its rupture front, until it arrests on a barrier. The resulting surface displacements qualitatively agree with geodetic observations and show landward and, from near the downdip limit, upward interseismic motions. These are rebound and reversed coseismically. This slip increases adjacent stresses, which are relaxed postseismically by afterslip and thereby produce persistent seaward motions. The wide range of observed physical phenomena, including back-propagation and repeated slip, and the agreement with laboratory results demonstrate that visco-elasto-plastic geodynamic models with rate-dependent friction form a new tool that can greatly contribute to our understanding of the seismic cycle at subduction zones.

  19. Development Report on the Idaho National Laboratory Sitewide Three-Dimensional Aquifer Model

    Energy Technology Data Exchange (ETDEWEB)

    Thomas R. Wood; Catherine M. Helm-Clark; Hai Huang; Swen Magnuson; Travis McLing; Brennon Orr; Michael J. Rohe; Mitchell A. Plummer; Robert Podgorney; Erik Whitmore; Michael S. Roddy

    2007-09-01

    A sub-regional scale, three-dimensional flow model of the Snake River Plain Aquifer was developed to support remediation decisions for Waste Area Group 10, Operable Unit 10 08 at the Idaho National Laboratory (INL) Site. This model has been calibrated primarily to water levels and secondarily to groundwater velocities interpreted from stable isotope disequilibrium studies and the movement of anthropogenic contaminants in the aquifer from facilities at the INL. The three-dimensional flow model described in this report is one step in the process of constructing a fully three-dimensional groundwater flow and contaminant transport model as prescribed in the Idaho National Engineering and Environmental Laboratory Operable Unit 10-08 Sitewide Groundwater Model Work Plan. An updated three-dimensional hydrogeologic conceptual model is presented along with the geologic basis for the conceptual model. Sediment-dominated three-dimensional volumes were used to represent the geology and constrain groundwater flow as part of the conceptual model. Hydrological, geochemical, and geological data were summarized and evaluated to infer aquifer behavior. A primary observation from development and evaluation of the conceptual model was that relative to flow on a regional scale, the aquifer can be treated with steady-state conditions. Boundary conditions developed for the three-dimensional flow model are presented along with inverse simulations that estimate parameterization of hydraulic conductivity. Inverse simulations were performed using the pilot-point method to estimate permeability distributions. Thermal modeling at the regional aquifer scale and at the sub-regional scale using the inverted permeabilities is presented to corroborate the results of the flow model. The results from the flow model show good agreement with simulated and observed water levels almost always within 1 meter. Simulated velocities show generally good agreement with some discrepancies in an interpreted low

  20. Laboratory cohabitation challenge model for shrimp hepatopancreatic microsporidiosis (HPM) caused by Enterocytozoon hepatopenaei (EHP).

    Science.gov (United States)

    Salachan, Paul Vinu; Jaroenlak, Pattana; Thitamadee, Siripong; Itsathitphaisarn, Ornchuma; Sritunyalucksana, Kallaya

    2017-01-05

    Enterocytozoon hepatopenaei (EHP) causes hepatopancreatic microsporidiosis (HPM) in shrimp. It is probably endemic in Australasia and was first characterized and named from the giant or black tiger shrimp Penaeus monodon from Thailand in 2009. Later, it was also found to infect exotic Penaeus vannamei imported for cultivation in Asia. HPM is not normally associated with shrimp mortality, but information from shrimp farmers indicates that it is associated with significant growth retardation that is not clearly noticeable until 2-3 months of cultivation. In order to study modes of HPM transmission and to test possible control measures, a laboratory challenge model was needed that would mimic the mode of infection in shrimp ponds. We describe successful transmission in a cohabitation model with natural E. hepatopenaei (EHP)-infected shrimp in closed, perforated plastic containers placed in aquaria together with free-swimming, uninfected shrimp. After a period of 14 days all the free-swimming shrimp tested positive by PCR (approximately 60% with heavy infections evident by 1-step PCR positive test results) and gave positive histological and in situ hybridization results for E. hepatopenaei (EHP) in the hepatopancreas. A laboratory cohabitation model for studying E. hepatopenaei (EHP) has been developed and used to confirm that E. hepatopenaei (EHP) can be directly transmitted horizontally among shrimp via water. The model will facilitate studies on methods to prevent the E. hepatopenaei (EHP) transmission.

  1. Application of a learning model in a traditional engineering classroom and laboratory

    Science.gov (United States)

    Brown, Cordelia Magalene

    The purpose of this dissertation research was to develop a learning model. This three-phase learning model involved administering pre-assessment inventories, facilitating collaborative exercises, and evaluating learning experiences. This dissertation explores the potential effects the learning model might have on course performance and overall academic performance. It focuses on potential relationships between course performance and learning style preferences data, demographics, and level of participation in phases of the learning model. It also examines relationships between confidence levels and the performance of course objectives. The first and final phases were applied to an introductory Electrical Engineering course. The second phase was applied to selected sections of the course. In the initial phase, students in all sections of the course were administered the Index of Learning Styles Questionnaire, a Myers-Briggs Type Indicator, and a pre-laboratory evaluation. In the second phase of the learning model, the students in the selected sections participated in weekly learning sessions. The weekly learning sessions provided students with practice problem sets and a structured environment to collaboratively practice problems and discuss course concepts. The final phase of the learning model evaluated the performance of students in both environments. From the application of the learning model, the effects that various instructional methods would have on students' performance in a laboratory type of environment were investigated. Overall, students that participated in the weekly learning sessions earned grades that were comparable or better than non-participants. Participants and non-participants in the weekly learning sessions with the Myers-Briggs Type Indicator (MBTI) Engineering Type (INTJ or ISTJ) earned about the same grade. Participants in the weekly learning sessions with types other than MBTI Engineering Type outperformed their peers of the same MBTI type

  2. Model prediction uncertainty of bromide and pesticides transport in laboratory column

    Science.gov (United States)

    Dusek, Jaromir; Dohnal, Michal; Snehota, Michal; Sobotkova, Martina; Ray, Chittaranjan; Vogel, Tomas

    2016-04-01

    Knowledge of transport parameters of reactive solutes such as pesticides is a prerequisite for reliable predictions of their fate and transport in soil porous systems. Water flow and transport of bromide tracer and five pesticides (atrazine, imazaquin, sulfometuron methyl, S-metolachlor, and imidacloprid) through an undisturbed soil column of tropical Oxisol were analyzed using a one-dimensional numerical model. Laboratory column leaching experiment with three flow interruptions was conducted. The applied numerical model is based on Richards' equation for solving water flow and the advection-dispersion equation for solving solute transport. A global optimization method was used to evaluate the model's sensitivity to transport parameters and the uncertainty of model predictions. Within the Monte Carlo modeling framework, multiple forward simulations searching through the parametric space, were executed to describe the observed breakthrough curves. All pesticides were found to be relatively mobile. Experimental data indicated significant non-conservative behavior of bromide tracer. All pesticides, with the exception of imidacloprid, were found less persistent. Three of the five pesticides (atrazine, sulfometuron methyl, and S-metolachlor) were better described by the linear kinetic sorption model, while the breakthrough curves of imazaquin and imidacloprid were more appropriately approximated using nonlinear instantaneous sorption. Sensitivity analysis suggested that the model is most sensitive to sorption distribution coefficient. The prediction limits contained most of the measured points of the experimental breakthrough curves, indicating adequate model concept and model structure for the description of transport processes in the soil column under study.

  3. Learning Laboratory.

    Science.gov (United States)

    Hay, Lyn; Callison, Daniel

    2000-01-01

    Considers the school library media center as an information learning laboratory. Topics include information literacy; Kuhlthau's Information Search Process model; inquiry theory and approach; discovery learning; process skills of laboratory science; the information scientist; attitudes of media specialists, teachers, and students; displays and Web…

  4. The Marine Virtual Laboratory (version 2.1): enabling efficient ocean model configuration

    Science.gov (United States)

    Oke, Peter R.; Proctor, Roger; Rosebrock, Uwe; Brinkman, Richard; Cahill, Madeleine L.; Coghlan, Ian; Divakaran, Prasanth; Freeman, Justin; Pattiaratchi, Charitha; Roughan, Moninya; Sandery, Paul A.; Schaeffer, Amandine; Wijeratne, Sarath

    2016-09-01

    The technical steps involved in configuring a regional ocean model are analogous for all community models. All require the generation of a model grid, preparation and interpolation of topography, initial conditions, and forcing fields. Each task in configuring a regional ocean model is straightforward - but the process of downloading and reformatting data can be time-consuming. For an experienced modeller, the configuration of a new model domain can take as little as a few hours - but for an inexperienced modeller, it can take much longer. In pursuit of technical efficiency, the Australian ocean modelling community has developed the Web-based MARine Virtual Laboratory (WebMARVL). WebMARVL allows a user to quickly and easily configure an ocean general circulation or wave model through a simple interface, reducing the time to configure a regional model to a few minutes. Through WebMARVL, a user is prompted to define the basic options needed for a model configuration, including the model, run duration, spatial extent, and input data. Once all aspects of the configuration are selected, a series of data extraction, reprocessing, and repackaging services are run, and a "take-away bundle" is prepared for download. Building on the capabilities developed under Australia's Integrated Marine Observing System, WebMARVL also extracts all of the available observations for the chosen time-space domain. The user is able to download the take-away bundle and use it to run the model of his or her choice. Models supported by WebMARVL include three community ocean general circulation models and two community wave models. The model configuration from the take-away bundle is intended to be a starting point for scientific research. The user may subsequently refine the details of the model set-up to improve the model performance for the given application. In this study, WebMARVL is described along with a series of results from test cases comparing WebMARVL-configured models to observations

  5. 9978 AND 9975 TYPE B PACKAGING INTERNAL DATA COLLECTION FEASIBILITY TESTING

    Energy Technology Data Exchange (ETDEWEB)

    Fogle, R.

    2012-05-07

    The objective of this report is to document the findings from a series of proof-of-concept tests performed by Savannah River National Laboratory (SRNL) R and D Engineering, for the DOE Packaging Certification Program to determine if a viable radio link could be established from within the stainless steel confines of several drum-style DOE certified Type B radioactive materials packagings. Two in-hand, off-the-shelf radio systems were tested. The first system was a Wi-Fi Librestream Onsight{trademark} camera with a Fortress ES820 Access Point and the second was the On-Ramp Wireless Ultra-Link Processing{trademark} (ULP) radio system. These radio systems were tested within the Model 9975 and 9978 Type B packagings at the SRNL. This report documents the test methods and results. A path forward will also be recommended.

  6. Evaluation Framework and Analyses for Thermal Energy Storage Integrated with Packaged Air Conditioning

    Energy Technology Data Exchange (ETDEWEB)

    Kung, F.; Deru, M.; Bonnema, E.

    2013-10-01

    Few third-party guidance documents or tools are available for evaluating thermal energy storage (TES) integrated with packaged air conditioning (AC), as this type of TES is relatively new compared to TES integrated with chillers or hot water systems. To address this gap, researchers at the National Renewable Energy Laboratory conducted a project to improve the ability of potential technology adopters to evaluate TES technologies. Major project outcomes included: development of an evaluation framework to describe key metrics, methodologies, and issues to consider when assessing the performance of TES systems integrated with packaged AC; application of multiple concepts from the evaluation framework to analyze performance data from four demonstration sites; and production of a new simulation capability that enables modeling of TES integrated with packaged AC in EnergyPlus. This report includes the evaluation framework and analysis results from the project.

  7. Botany Facility. Thermal Control (TC) subsystem test report on experiment container of laboratory model and breadboard centrifuge

    Science.gov (United States)

    Fischer, W.

    1986-11-01

    The Botany Facility TC (Thermal Control or Thermocouple) subsystem was tested in the environmental laboratory. All data could be generated within the required accuracy and to the required extent. The TC-subsystems of the Laboratory Model and Experiment Container and Centrifuge were successfully tested.

  8. Leveraging the laboratory response network model for the global health security agenda.

    Science.gov (United States)

    Mangal, Chris N; Maryogo-Robinson, Lucy

    2014-01-01

    Promoting global health security as an international priority is a challenge; the US Centers for Disease Control and Prevention (CDC) in its Global Health Security Agenda has articulated the importance of accelerating progress toward a world safe and secure from infectious disease threats. The goals are to (1) prevent and reduce the likelihood of outbreaks-natural, accidental, or intentional; (2) detect threats early to save lives; and (3) respond rapidly and effectively using multisectoral, international coordination and communication. Foundational to this agenda is the World Health Organization (WHO) Revised International Health Regulations (IHR) of 2005, which provide the legal framework for countries to strengthen their health systems in order to be able to respond to any public health emergency of international concern. This article proposes leveraging the distributed structure of the US-managed Laboratory Response Network for Biological Threats Preparedness (LRN-B) to develop the core capacity of laboratory testing and to fulfill the laboratory-strengthening component of the Global Health Security Agenda. The LRN model offers an effective mechanism to detect and respond to public health emergencies of international concern.

  9. Development of a prediction model on the acceptance of electronic laboratory notebooks in academic environments.

    Science.gov (United States)

    Kloeckner, Frederik; Farkas, Robert; Franken, Tobias; Schmitz-Rode, Thomas

    2014-04-01

    Documentation of research data plays a key role in the biomedical engineering innovation processes. It makes an important contribution to the protection of intellectual property, the traceability of results and fulfilling the regulatory requirement. Because of the increasing digitalization in laboratories, an electronic alternative to the commonly-used paper-bound notebooks could contribute to the production of sophisticated documentation. However, compared to in an industrial environment, the use of electronic laboratory notebooks is not widespread in academic laboratories. Little is known about the acceptance of an electronic documentation system and the underlying reasons for this. Thus, this paper aims to establish a prediction model on the potential preference and acceptance of scientists either for paper-based or electronic documentation. The underlying data for the analysis originate from an online survey of 101 scientists in industrial, academic and clinical environments. Various parameters were analyzed to identify crucial factors for the system preference using binary logistic regression. The analysis showed significant dependency between the documentation system preference and the supposed workload associated with the documentation system (pnotebook before implementation.

  10. Labs21 Laboratory Modeling Guidelines using ASHRAE 90.1-1999

    Energy Technology Data Exchange (ETDEWEB)

    Reilly, Susan; Walsh, Michael; Graham, Carl; Maor, Itzhak; Mathew, Paul; Porter, Fred; Sartor, Dale; Van Geet, Otto

    2005-10-01

    The following is a guideline for energy modeling of laboratory spaces in a building in accordance with the Energy Cost Budget method described in ASHRAE 90.1-1999 Energy Standard for Buildings Except Low-Rise Residential Buildings. For the purposes of this document, a laboratory is defined as any space requiring once through ventilation systems (recirculation of air to other spaces in a building is not allowed). To accomplish this, ventilation systems in laboratories typically provide 100% outside air to the occupied space. The guideline is structured similarly to the ASHRAE 90.1-99 standard. Only those sections being clarified or modified are discussed in the guideline; all other sections should be followed as defined in the standard. Specifically, those sections that are affected include the following: (1) 6.3.3.1 - Fan Power Limitation (modification); (2) 6.3.7.2 - Fume Hoods (modification); (3) 11.3.11 - Schedules (modification); (4) 11.4.3 - HVAC Systems (clarification); (5) 11.4.3 (h) Budget Supply-Air-to-Room Air Temperature Difference (modification); (6) 11.4.3(i) - Fan system efficiency (modification); and (7) Table 11.4.3A - Budget System Descriptions (modification). For energy efficiency measures that are not explicitly addressed by the standard, we recommend application of Section 11.5, Exceptional Calculation Methods. This guideline does not cover the details of such calculation methods.

  11. Simulation of the hydraulic performance of highway filter drains through laboratory models and stormwater management tools.

    Science.gov (United States)

    Sañudo-Fontaneda, Luis A; Jato-Espino, Daniel; Lashford, Craig; Coupe, Stephen J

    2017-05-23

    Road drainage is one of the most relevant assets in transport infrastructure due to its inherent influence on traffic management and road safety. Highway filter drains (HFDs), also known as "French Drains", are the main drainage system currently in use in the UK, throughout 7000 km of its strategic road network. Despite being a widespread technique across the whole country, little research has been completed on their design considerations and their subsequent impact on their hydraulic performance, representing a gap in the field. Laboratory experiments have been proven to be a reliable indicator for the simulation of the hydraulic performance of stormwater best management practices (BMPs). In addition to this, stormwater management tools (SMT) have been preferentially chosen as a design tool for BMPs by practitioners from all over the world. In this context, this research aims to investigate the hydraulic performance of HFDs by comparing the results from laboratory simulation and two widely used SMT such as the US EPA's stormwater management model (SWMM) and MicroDrainage®. Statistical analyses were applied to a series of rainfall scenarios simulated, showing a high level of accuracy between the results obtained in laboratory and using SMT as indicated by the high and low values of the Nash-Sutcliffe and R (2) coefficients and root-mean-square error (RMSE) reached, which validated the usefulness of SMT to determine the hydraulic performance of HFDs.

  12. Grooming. Learning Activity Package.

    Science.gov (United States)

    Stark, Pamela

    This learning activity package on grooming for health workers is one of a series of 12 titles developed for use in health occupations education programs. Materials in the package include objectives, a list of materials needed, information sheets, reviews (self evaluations) of portions of the content, and answers to reviews. These topics are…

  13. Packaging issues: avoiding delamination.

    Science.gov (United States)

    Hall, R

    2005-10-01

    Manufacturers can minimise delamination occurrence by applying the appropriate packaging design and process features. The end user can minimise the impact of fibre tear and reduce subsequent delamination by careful package opening. The occasional inconvenient delamination is a small price to pay for the high level of sterility assurance that comes with the use of Tyvek.

  14. WASTE PACKAGE TRANSPORTER DESIGN

    Energy Technology Data Exchange (ETDEWEB)

    D.C. Weddle; R. Novotny; J. Cron

    1998-09-23

    The purpose of this Design Analysis is to develop preliminary design of the waste package transporter used for waste package (WP) transport and related functions in the subsurface repository. This analysis refines the conceptual design that was started in Phase I of the Viability Assessment. This analysis supports the development of a reliable emplacement concept and a retrieval concept for license application design. The scope of this analysis includes the following activities: (1) Assess features of the transporter design and evaluate alternative design solutions for mechanical components. (2) Develop mechanical equipment details for the transporter. (3) Prepare a preliminary structural evaluation for the transporter. (4) Identify and recommend the equipment design for waste package transport and related functions. (5) Investigate transport equipment interface tolerances. This analysis supports the development of the waste package transporter for the transport, emplacement, and retrieval of packaged radioactive waste forms in the subsurface repository. Once the waste containers are closed and accepted, the packaged radioactive waste forms are termed waste packages (WP). This terminology was finalized as this analysis neared completion; therefore, the term disposal container is used in several references (i.e., the System Description Document (SDD)) (Ref. 5.6). In this analysis and the applicable reference documents, the term ''disposal container'' is synonymous with ''waste package''.

  15. User friendly packaging

    DEFF Research Database (Denmark)

    Geert Jensen, Birgitte

    2010-01-01

    Most consumers have experienced occasional problems with opening packaging. Tomato sauce from the tinned mackerel splattered all over the kitchen counter, the unrelenting pickle jar lid, and the package of sliced ham that cannot be opened without a knife or a pair of scissors. The research project...

  16. The Development of Basic Animal Husbandry Learning Package

    OpenAIRE

    Sri Suryaningsih

    2015-01-01

    Pengembangan Paket Pembelajaran Dasar-dasar Peternakan Abstract: The purpose this research is to generate a package of learning development basics animal husbandry in accordance with the characteristics of the students and the subject and test the fea-sibility of the resulting learning package. The development of learning packages using the model of Dick, Carey & Carey (2001). The results of product assessment the package of learning the basics of animal husbandry is included in the quali...

  17. Laboratory and Modeling Evaluations in Support of Field Testing for Desiccation at the Hanford Site

    Energy Technology Data Exchange (ETDEWEB)

    Truex, Michael J.; Oostrom, Martinus; Freedman, Vicky L.; Strickland, Christopher E.; Wietsma, Thomas W.; Tartakovsky, Guzel D.; Ward, Anderson L.

    2011-02-23

    The Deep Vadose Zone Treatability Test Plan for the Hanford Central Plateau includes testing of the desiccation technology as a potential technology to be used in conjunction with surface infiltration control to limit the flux of technetium and other contaminants in the vadose zone to the groundwater. Laboratory and modeling efforts were conducted to investigate technical uncertainties related to the desiccation process and its impact on contaminant transport. This information is intended to support planning, operation, and interpretation of a field test for desiccation in the Hanford Central Plateau.

  18. Magnetic field reversals: the geodynamo, laboratory experiments and models (Lewis Fry Richardson Medal Lecture)

    Science.gov (United States)

    Fauve, S.

    2009-04-01

    I will first compare reversals of Earth's magnetic field known from palaeomagnetic data to the ones observed in a laboratory experiment for the magnetic field generated by a turbulent flow of liquid sodium (VKS experiment). Despite major differences between the flow in Earth's core and in the experiment, both systems display reversals that share a lot of similar properties. I will understand them using a simple model in the framework of low dynamical system theory. Finally, I will discuss what can be learnt from numerical simulations.

  19. A Model Computing Laboratory for University Schools of Nursing: The Michigan Experience

    Science.gov (United States)

    Schultz, Samuel

    1982-01-01

    This paper presents an historical view of a prototype four-phase developmental system for university level instruction in computing and data analysis for nursing curricula. Specific hardware, instrumented classrooms and computing laboratory designs are discussed as they relate to typical program growth. Although the historical view presents a system which spans more than 13 years of growth, the paper concludes with a presentation of the current state-of-the-art microcomputer system and an archetypical four-phase system model potentially useful for other health science computing curricula.

  20. Development of a generic auto-calibration package for regional ecological modeling and application in the Central Plains of the United States

    Science.gov (United States)

    Wu, Yiping; Liu, Shuguang; Li, Zhengpeng; Dahal, Devendra; Young, Claudia J.; Schmidt, Gail L.; Liu, Jinxun; Davis, Brian; Sohl, Terry L.; Werner, Jeremy M.; Oeding, Jennifer

    2014-01-01

    Process-oriented ecological models are frequently used for predicting potential impacts of global changes such as climate and land-cover changes, which can be useful for policy making. It is critical but challenging to automatically derive optimal parameter values at different scales, especially at regional scale, and validate the model performance. In this study, we developed an automatic calibration (auto-calibration) function for a well-established biogeochemical model—the General Ensemble Biogeochemical Modeling System (GEMS)-Erosion Deposition Carbon Model (EDCM)—using data assimilation technique: the Shuffled Complex Evolution algorithm and a model-inversion R package—Flexible Modeling Environment (FME). The new functionality can support multi-parameter and multi-objective auto-calibration of EDCM at the both pixel and regional levels. We also developed a post-processing procedure for GEMS to provide options to save the pixel-based or aggregated county-land cover specific parameter values for subsequent simulations. In our case study, we successfully applied the updated model (EDCM-Auto) for a single crop pixel with a corn–wheat rotation and a large ecological region (Level II)—Central USA Plains. The evaluation results indicate that EDCM-Auto is applicable at multiple scales and is capable to handle land cover changes (e.g., crop rotations). The model also performs well in capturing the spatial pattern of grain yield production for crops and net primary production (NPP) for other ecosystems across the region, which is a good example for implementing calibration and validation of ecological models with readily available survey data (grain yield) and remote sensing data (NPP) at regional and national levels. The developed platform for auto-calibration can be readily expanded to incorporate other model inversion algorithms and potential R packages, and also be applied to other ecological models.

  1. Advanced flip chip packaging

    CERN Document Server

    Lai, Yi-Shao; Wong, CP

    2013-01-01

    Advanced Flip Chip Packaging presents past, present and future advances and trends in areas such as substrate technology, material development, and assembly processes. Flip chip packaging is now in widespread use in computing, communications, consumer and automotive electronics, and the demand for flip chip technology is continuing to grow in order to meet the need for products that offer better performance, are smaller, and are environmentally sustainable. This book also: Offers broad-ranging chapters with a focus on IC-package-system integration Provides viewpoints from leading industry executives and experts Details state-of-the-art achievements in process technologies and scientific research Presents a clear development history and touches on trends in the industry while also discussing up-to-date technology information Advanced Flip Chip Packaging is an ideal book for engineers, researchers, and graduate students interested in the field of flip chip packaging.

  2. Effects of activity and energy budget balancing algorithm on laboratory performance of a fish bioenergetics model

    Science.gov (United States)

    Madenjian, Charles P.; David, Solomon R.; Pothoven, Steven A.

    2012-01-01

    We evaluated the performance of the Wisconsin bioenergetics model for lake trout Salvelinus namaycush that were fed ad libitum in laboratory tanks under regimes of low activity and high activity. In addition, we compared model performance under two different model algorithms: (1) balancing the lake trout energy budget on day t based on lake trout energy density on day t and (2) balancing the lake trout energy budget on day t based on lake trout energy density on day t + 1. Results indicated that the model significantly underestimated consumption for both inactive and active lake trout when algorithm 1 was used and that the degree of underestimation was similar for the two activity levels. In contrast, model performance substantially improved when using algorithm 2, as no detectable bias was found in model predictions of consumption for inactive fish and only a slight degree of overestimation was detected for active fish. The energy budget was accurately balanced by using algorithm 2 but not by using algorithm 1. Based on the results of this study, we recommend the use of algorithm 2 to estimate food consumption by fish in the field. Our study results highlight the importance of accurately accounting for changes in fish energy density when balancing the energy budget; furthermore, these results have implications for the science of evaluating fish bioenergetics model performance and for more accurate estimation of food consumption by fish in the field when fish energy density undergoes relatively rapid changes.

  3. Climate systems modeling on massively parallel processing computers at Lawrence Livermore National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Wehner, W.F.; Mirin, A.A.; Bolstad, J.H. [and others

    1996-09-01

    A comprehensive climate system model is under development at Lawrence Livermore National Laboratory. The basis for this model is a consistent coupling of multiple complex subsystem models, each describing a major component of the Earth`s climate. Among these are general circulation models of the atmosphere and ocean, a dynamic and thermodynamic sea ice model, and models of the chemical processes occurring in the air, sea water, and near-surface land. The computational resources necessary to carry out simulations at adequate spatial resolutions for durations of climatic time scales exceed those currently available. Distributed memory massively parallel processing (MPP) computers promise to affordably scale to the computational rates required by directing large numbers of relatively inexpensive processors onto a single problem. We have developed a suite of routines designed to exploit current generation MPP architectures via domain and functional decomposition strategies. These message passing techniques have been implemented in each of the component models and in their coupling interfaces. Production runs of the atmospheric and oceanic components performed on the National Environmental Supercomputing Center (NESC) Cray T3D are described.

  4. A Wildfire Behavior Modeling System at Los Alamos National Laboratory for Operational Applications

    Energy Technology Data Exchange (ETDEWEB)

    S.W. Koch; R.G.Balice

    2004-11-01

    To support efforts to protect facilities and property at Los Alamos National Laboratory from damages caused by wildfire, we completed a multiyear project to develop a system for modeling the behavior of wildfires in the Los Alamos region. This was accomplished by parameterizing the FARSITE wildfire behavior model with locally gathered data representing topography, fuels, and weather conditions from throughout the Los Alamos region. Detailed parameterization was made possible by an extensive monitoring network of permanent plots, weather towers, and other data collection facilities. We also incorporated a database of lightning strikes that can be used individually as repeatable ignition points or can be used as a group in Monte Carlo simulation exercises and in other randomization procedures. The assembled modeling system was subjected to sensitivity analyses and was validated against documented fires, including the Cerro Grande Fire. The resulting modeling system is a valuable tool for research and management. It also complements knowledge based on professional expertise and information gathered from other modeling technologies. However, the modeling system requires frequent updates of the input data layers to produce currently valid results, to adapt to changes in environmental conditions within the Los Alamos region, and to allow for the quick production of model outputs during emergency operations.

  5. Growth of Microbial Populations. Mathematical Modeling, Laboratory Exercises, and Model-Based Data Analysis

    Science.gov (United States)

    Juska, Alfonsas; Gedminiene, Genovaite; Ivanec, Ruta

    2006-01-01

    This paper has arisen as a result of teaching Models in Biology to undergraduates of Bioengineering at the Gediminas Technical University of Vilnius. The aim is to teach the students to use a fresh approach to the problems they are familiar with, to come up with an articulate verbal model after a mental effort, to express it in rigorous…

  6. Severities of transportation accidents involving large packages

    Energy Technology Data Exchange (ETDEWEB)

    Dennis, A.W.; Foley, J.T. Jr.; Hartman, W.F.; Larson, D.W.

    1978-05-01

    The study was undertaken to define in a quantitative nonjudgmental technical manner the abnormal environments to which a large package (total weight over 2 tons) would be subjected as the result of a transportation accident. Because of this package weight, air shipment was not considered as a normal transportation mode and was not included in the study. The abnormal transportation environments for shipment by motor carrier and train were determined and quantified. In all cases the package was assumed to be transported on an open flat-bed truck or an open flat-bed railcar. In an earlier study, SLA-74-0001, the small-package environments were investigated. A third transportation study, related to the abnormal environment involving waterways transportation, is now under way at Sandia Laboratories and should complete the description of abnormal transportation environments. Five abnormal environments were defined and investigated, i.e., fire, impact, crush, immersion, and puncture. The primary interest of the study was directed toward the type of large package used to transport radioactive materials; however, the findings are not limited to this type of package but can be applied to a much larger class of material shipping containers.

  7. Antimicrobial food packaging: potential and pitfalls

    Science.gov (United States)

    Malhotra, Bhanu; Keshwani, Anu; Kharkwal, Harsha

    2015-01-01

    Nowadays food preservation, quality maintenance, and safety are major growing concerns of the food industry. It is evident that over time consumers’ demand for natural and safe food products with stringent regulations to prevent food-borne infectious diseases. Antimicrobial packaging which is thought to be a subset of active packaging and controlled release packaging is one such promising technology which effectively impregnates the antimicrobial into the food packaging film material and subsequently delivers it over the stipulated period of time to kill the pathogenic microorganisms affecting food products thereby increasing the shelf life to severe folds. This paper presents a picture of the recent research on antimicrobial agents that are aimed at enhancing and improving food quality and safety by reduction of pathogen growth and extension of shelf life, in a form of a comprehensive review. Examination of the available antimicrobial packaging technologies is also presented along with their significant impact on food safety. This article entails various antimicrobial agents for commercial applications, as well as the difference between the use of antimicrobials under laboratory scale and real time applications. Development of resistance amongst microorganisms is considered as a future implication of antimicrobials with an aim to come up with actual efficacies in extension of shelf life as well as reduction in bacterial growth through the upcoming and promising use of antimicrobials in food packaging for the forthcoming research down the line. PMID:26136740

  8. Predictive models for deposition of inhaled diesel exhaust particles in humans and laboratory species

    Energy Technology Data Exchange (ETDEWEB)

    Yu, C.P.; Xu, G.B. (State Univ. of New York at Buffalo, Amherst (USA))

    1987-01-01

    Mathematical and computer models of the respiratory tracts of human beings and of laboratory animals (rats, hamsters, guinea pigs) were used to estimate the deposition patterns of inhaled diesel exhaust particles from automobile emissions. Our goal was to be able to predict the relation between exposure to diesel exhaust particles and the deposition of these particles in the lungs of humans of various ages. Diesel exhaust particles are aggregates with a mass median aerodynamic diameter of approximately 0.2 micron. Their actual size depends on the conditions under which they are generated. Using an appropriate particle model, we derived mathematical expressions that describe the effects of diffusion, sedimentation, impaction, and interception on the deposition of these particles. Because of their small size, we found that most diesel exhaust particles deposited through diffusion, and that the role of the other mechanisms was minor. Anatomical models of the human lung from birth to adulthood, as well as models of the lungs of laboratory species were formulated mathematically using available morphometric data. We used these lung models, together with the corresponding ventilation conditions of each species, to calculate deposition of diesel exhaust particles in the lungs. Under normal breathing conditions, we calculated that 7 to 13 percent (depending on particle size) of inhaled diesel exhaust particles deposit in the alveolar region of the adult human lung. Although the breathing mode (nose or mouth breathing) did not appear to affect alveolar deposition, increasing the minute ventilation increased alveolar deposition significantly. The calculated deposition patterns for diesel exhaust particles in younger humans (under age 25) were similar.

  9. O sistema globalmente harmonizado de classificação e rotulagem de produtos químicos (GHS: uma introdução para sua aplicação em laboratórios de ensino e pesquisa acadêmica The globally harmonised system of classification, labelling and packaging of chemicals (GHS: an introduction to its application in academic teaching and research laboratories

    Directory of Open Access Journals (Sweden)

    Wilhelm Martin Wallau

    2013-01-01

    Full Text Available The present article provides an overview of the Globally Harmonised System of Classification, Labelling and Packaging of Chemicals (GHS and its implementation in Brazil. Although Classification and Packaging is beyond the scope of the responsibility of academic chemists, labelling of chemicals used in academic laboratories will be required by the competent authorities to ensure the safety of students and staff. Therefore, academic teachers and researchers responsible should be familiarised with the GHS principles outlined here and at least be able to label, by applying these principles, mixtures of substances previously classified by the competent authorities.

  10. The development and testing of a 2D laboratory seismic modelling system for heterogeneous structure investigations

    Science.gov (United States)

    Mo, Yike; Greenhalgh, Stewart A.; Robertsson, Johan O. A.; Karaman, Hakki

    2015-05-01

    Lateral velocity variations and low velocity near-surface layers can produce strong scattered and guided waves which interfere with reflections and lead to severe imaging problems in seismic exploration. In order to investigate these specific problems by laboratory seismic modelling, a simple 2D ultrasonic model facility has been recently assembled within the Wave Propagation Lab at ETH Zurich. The simulated geological structures are constructed from 2 mm thick metal and plastic sheets, cut and bonded together. The experiments entail the use of a piezoelectric source driven by a pulse amplifier at ultrasonic frequencies to generate Lamb waves in the plate, which are detected by piezoelectric receivers and recorded digitally on a National Instruments recording system, under LabVIEW software control. The 2D models employed were constructed in-house in full recognition of the similitude relations. The first heterogeneous model features a flat uniform low velocity near-surface layer and deeper dipping and flat interfaces separating different materials. The second model is comparable but also incorporates two rectangular shaped inserts, one of low velocity, the other of high velocity. The third model is identical to the second other than it has an irregular low velocity surface layer of variable thickness. Reflection as well as transmission experiments (crosshole & vertical seismic profiling) were performed on each model. The two dominant Lamb waves recorded are the fundamental symmetric mode (non-dispersive) and the fundamental antisymmetric (flexural) dispersive mode, the latter normally being absent when the source transducer is located on a model edge but dominant when it is on the flat planar surface of the plate. Experimental group and phase velocity dispersion curves were determined and plotted for both modes in a uniform aluminium plate. For the reflection seismic data, various processing techniques were applied, as far as pre-stack Kirchhoff migration. The

  11. Laboratory Activities

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Christopher F.; Serne, R. Jeffrey

    2008-01-17

    This chapter summarizes the laboratory activities performed by PNNL’s Vadose Zone Characterization Project in support of the Tank Farm Vadose Zone Program, led by CH2M HILL Hanford Group, Inc. The results of these studies are contained in numerous reports (Lindenmeier et al. 2002; Serne et al. 2002a, 2002b, 2002c, 2002d, 2002e; Lindenmeier et al. 2003; Serne et al. 2004a, 2004b; Brown et al. 2005, 2006a, 2007; Serne et al. 2007) and have generated much of the data reported in Chapter 22 (Geochemistry-Contaminant Movement), Appendix G (Geochemistry-Contaminant Movement), and Cantrell et al. (2007, SST WMA Geochemistry Data Package – in preparation). Sediment samples and characterization results from PNNL’s Vadose Zone Characterization Project are also shared with other science and technology (S&T) research projects, such as those summarized in Chapter 12 (Associated Science Activities).

  12. Modular Packaging Development: Incorporating a modular perspective in the packaging design process

    OpenAIRE

    Karlsson, John

    2013-01-01

    This report presents the result of a research project conducted in 2012-2013 that aimed to adjust the existing modularity theories so that they could be used in packaging development. The study resulted in a model that can be incorporated into an existing packaging design process, thereby complementing this with aspects of modularity. The research project was conducted in close collaboration with Ericsson.

  13. Packaging Concerns/Techniques for Large Devices

    Science.gov (United States)

    Sampson, Michael J.

    2009-01-01

    This slide presentation reviews packaging challenges and options for electronic parts. The presentation includes information about non-hermetic packages, space challenges for packaging and complex package variations.

  14. Computational Modeling of Laboratory X-ray Emission due to Low-Energy Collisions of H-like and He-like ions with H2

    Science.gov (United States)

    Miller, Ansley; Mullen, Patrick Dean; Cumbee, Renata; Stancil, Phillip C.; Leutenegger, Maurice A.

    2016-06-01

    Charge exchange between highly-charged ions and neutral molecules occurs when the solar wind, or other astrophysical plasmas, collide with cool gas. This process emits observable X-rays with specific line intensities. Recent CX experiments at Lawrence Livermore National Laboratory measured the X-ray hardness ratios of low-energy collisions between hydrogen- and helium-like ions with H2 (Leutenegger et al. 2010). Using our recently developed X-ray modeling package, Kronos_v2 (Mullen et al. 2016), which utilizes multi-channel Landau-Zener charge exchange cross sections, we have computed theoretical hydrogen-like hardness ratios to aid in interpretation of the experimental data. While the computed hardness ratios are somewhat smaller than the experiment, it shows better agreement than earlier classical trajectory predictions. We are also in the process of building Kronos_v3; further enhancing the comprehensive charge exchange database to include helium-like and multielectron ions to allow for comparison with experiments and for models of hot astrophysical environments such as supernova remnants, star-forming galaxies, and galaxy clusters.Leutenegger, M. et al. 2010, Phys. Rev. Lett., 105, 063201Mullen, P. D. et al., 2016, ApJS, in press

  15. Laboratory model of the cardiovascular system for experimental demonstration of pulse wave propagation

    Science.gov (United States)

    Stojadinović, Bojana; Nestorović, Zorica; Djurić, Biljana; Tenne, Tamar; Zikich, Dragoslav; Žikić, Dejan

    2017-03-01

    The velocity by which a disturbance moves through the medium is the wave velocity. Pulse wave velocity is among the key parameters in hemodynamics. Investigation of wave propagation through the fluid-filled elastic tube has a great importance for the proper biophysical understanding of the nature of blood flow through the cardiovascular system. Here, we present a laboratory model of the cardiovascular system. We have designed an experimental setup which can help medical and nursing students to properly learn and understand basic fluid hemodynamic principles, pulse wave and the phenomenon of wave propagation in blood vessels. Demonstration of wave propagation allowed a real time observation of the formation of compression and expansion waves by students, thus enabling them to better understand the difference between the two waves, and also to measure the pulse wave velocity for different fluid viscosities. The laboratory model of the cardiovascular system could be useful as an active learning methodology and a complementary tool for understanding basic principles of hemodynamics.

  16. Assessing pharmacokinetics of different doses of fosfomycin in laboratory rats enables adequate exposure for pharmacodynamic models.

    Science.gov (United States)

    Poeppl, Wolfgang; Lingscheid, Tilman; Bernitzky, Dominik; Donath, Oliver; Reznicek, Gottfried; Zeitlinger, Markus; Burgmann, Heinz

    2014-01-01

    Fosfomycin has been the subject of numerous pharmacodynamic in vivo models in recent years. The present study set out to determine fosfomycin pharmacokinetics in laboratory rats to enable adequate dosing regimens in future rodent models. Fosfomycin was given intraperitoneally as single doses of 75, 200 and 500 mg/kg bodyweight to 4 Sprague-Dawley rats per dose group. Blood samples were collected over 8 h and fosfomycin concentrations were determined by HPLC-mass spectrometry. Fosfomycin showed a dose-proportional pharmacokinetic profile indicated by a correlation of 0.99 for maximum concentration and area under the concentration-time curve (AUC). The mean AUC0-8 after intraperitoneal administration of 75, 200 or 500 mg/kg bodyweight fosfomycin were 109.4, 387.0 and 829.1 µg·h/ml, respectively. In conclusion, a dosing regimen of 200-500 mg/kg 3 times daily is appropriate to obtain serum concentrations in laboratory rats, closely mimicking human serum concentrations over time.

  17. Modeling extreme wave heights from laboratory experiments with the nonlinear Schrödinger equation

    Science.gov (United States)

    Zhang, H. D.; Guedes Soares, C.; Cherneva, Z.; Onorato, M.

    2014-04-01

    Spatial variation of nonlinear wave groups with different initial envelope shapes is theoretically studied first, confirming that the simplest nonlinear theoretical model is capable of describing the evolution of propagating wave packets in deep water. Moreover, three groups of laboratory experiments run in the wave basin of CEHIPAR (Canal de Experiencias Hidrodinámicas de El Pardo, known also as El Pardo Model Basin) was founded in 1928 by the Spanish Navy. are systematically compared with the numerical simulations of the nonlinear Schrödinger equation. Although a little overestimation is detected, especially in the set of experiments characterized by higher initial wave steepness, the numerical simulation still displays a high degree of agreement with the laboratory experiments. Therefore, the nonlinear Schrödinger equation catches the essential characteristics of the extreme waves and provides an important physical insight into their generation. The modulation instability, resulting from the quasi-resonant four-wave interaction in a unidirectional sea state, can be indicated by the coefficient of kurtosis, which shows an appreciable correlation with the extreme wave height and hence is used in the modified Edgeworth-Rayleigh distribution. Finally, some statistical properties on the maximum wave heights in different sea states have been related with the initial Benjamin-Feir index.

  18. Laboratory light scattering from regolith surface and simulation of data by Hapke model

    CERN Document Server

    Deb, S

    2015-01-01

    The small atmosphereless objects of our solar system, such as asteroids, the moon are covered by layer of dust particles known as regolith, formed by meteoritic impact. The light scattering studies of such dust layer by laboratory experiment and numerical simulation are two important tools to investigate their physical properties. In the present work, the light scattered from a layer of dust particles, containing 0.3{\\mu}m Al2O3 at wavelength 632.8 nm is analysed. This work has been performed by using a light scattering instrument 'ellipsometer', at the Department of Physics, Assam Universiy, Silchar, India. Through this experiment, we generated in laboratory the photometric and polarimetric phase curves of light scattered from such a layer. In order to numerically simulate this data, we used Hapke's model combined with Mie's single particle scattering properties. The perpendicular and parallel components of single particle albedo and the phase function were derived from Mie theory. By using the Hapke's model...

  19. Computed tomography study of VAPEX process in laboratory 3D model

    Energy Technology Data Exchange (ETDEWEB)

    Wu, G.Q.; Kantzas, A. [Calgary Univ., AB (Canada). Tomographic Imaging and Porous Media Laboratory; Salama, D. [Nexen Inc., Calgary, AB (Canada)

    2008-07-01

    This paper provided details of a 3-D laboratory model of the VAPEX process that used computerized tomography (CT) to examine vapour chamber expansion behaviour in longitudinal and radial directions. The model was comprised of an aluminum cylinder with 2 slotted tubes installed inside to act as injection and production wells. Propane was used as a solvent with heavy oil. The results of experiments conducted with the model showed that the V shape vapour chamber expansion pattern predicted by the 2-D model was a localized phenomenon. The dominant characteristic of the vapour chamber was an overriding of the injected solvent at the top of the model. The overriding was attributed to gravity segregation. The study also showed that longitudinal expansion was more significant than upwards expansion during the early stages of the VAPEX process. Oil production performance was then examined using different solvent injection rates. An analysis of the CT images was conducted to obtain model porosity, density, and oil saturation profiles. The study demonstrated that pressure cycles caused oil to be produced intermittently. Oil swelling by solvent gas dissolution was an important recovery mechanism. It was concluded that solvent soaking can be used to recover additional residual oil during the VAPEX process. 19 refs., 1 tab., 24 figs.

  20. Comparison of Model Predictions and Laboratory Observations of Transgene Frequencies in Continuously-Breeding Mosquito Populations.

    Science.gov (United States)

    Valerio, Laura; North, Ace; Collins, C Matilda; Mumford, John D; Facchinelli, Luca; Spaccapelo, Roberta; Benedict, Mark Q

    2016-09-22

    The persistence of transgenes in the environment is a consideration in risk assessments of transgenic organisms. Combining mathematical models that predict the frequency of transgenes and experimental demonstrations can validate the model predictions, or can detect significant biological deviations that were neither apparent nor included as model parameters. In order to assess the correlation between predictions and observations, models were constructed to estimate the frequency of a transgene causing male sexual sterility in simulated populations of a malaria mosquito Anopheles gambiae that were seeded with transgenic females at various proportions. Concurrently, overlapping-generation laboratory populations similar to those being modeled were initialized with various starting transgene proportions, and the subsequent proportions of transgenic individuals in populations were determined weekly until the transgene disappeared. The specific transgene being tested contained a homing endonuclease gene expressed in testes, I-PpoI, that cleaves the ribosomal DNA and results in complete male sexual sterility with no effect on female fertility. The transgene was observed to disappear more rapidly than the model predicted in all cases. The period before ovipositions that contained no transgenic progeny ranged from as little as three weeks after cage initiation to as long as 11 weeks.