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Sample records for kupffer cell symposium

  1. Kupffer Cells in the Liver

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    Dixon, Laura J.; Barnes, Mark; Tang, Hui; Pritchard, Michele T.; Nagy, Laura E.

    2016-01-01

    Kupffer cells are a critical component of the mononuclear phagocytic system and are central to both the hepatic and systemic response to pathogens. Kupffer cells are reemerging as critical mediators of both liver injury and repair. Kupffer cells exhibit a tremendous plasticity; depending on the local metabolic and immune environment, then can express a range of polarized phenotypes, from the proinflammatory M1 phenotype to the alternative/M2 phenotype. Multiple M2 phenotypes can be distinguished, each involved in the resolution of inflammation and wound healing. Here, we have provided an update on recent research that has contributed to the developing delineation of the contribution of Kupffer cells to different types of liver injury, with an emphasis on alcoholic and nonalcoholic liver diseases. These recent advances in our understanding of Kupffer cell function and regulation will likely provide new insights into the potential for therapeutic manipulation of Kupffer cells to promote the resolution of inflammation and enhance wound healing in liver disease. PMID:23720329

  2. Kinetics of liver macrophages (Kupffer cells) in SIV-infected macaques

    International Nuclear Information System (INIS)

    Ahsan, Muhammad H.; Gill, Amy F.; Alvarez, Xavier; Lackner, Andrew A.; Veazey, Ronald S.

    2013-01-01

    Since the liver drains antigens from the intestinal tract, and since the intestinal tract is a major site of viral replication, we examined the dynamics of liver macrophages (Kupffer cells) throughout SIV infection. Absolute numbers of Kupffer cells increased in the livers in acute infection, and in animals with AIDS. Significantly higher percentages of proliferating (BrdU+) Kupffer cells were detected in acute infection and in AIDS with similar trends in blood monocytes. Significantly higher percentages of apoptotic (AC3+) Kupffer cells were also found in acute and AIDS stages. However, productively infected cells were not detected in liver of 41/42 animals examined, despite abundant infected cells in gut and lymph nodes of all animals. Increased rates of Kupffer cell proliferation resulting in an increase in Kupffer cells without productive infection indicate SIV infection affects Kupffer cells, but the liver does not appear to be a major site of productive viral replication. - Highlights: • Kupffer cells increase in the liver of SIV-infected macaques. • Increased proliferation and apoptosis of Kupffer cells occurs in SIV infection. • Productively infected cells are rarely detected in the liver. • The liver is not a major site for SIV replication

  3. Tobacco and e-cigarette products initiate Kupffer cell inflammatory responses.

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    Rubenstein, David A; Hom, Sarah; Ghebrehiwet, Berhane; Yin, Wei

    2015-10-01

    Kupffer cells are liver resident macrophages that are responsible for screening and clearing blood of pathogens and foreign particles. It has recently been shown that Kupffer cells interact with platelets, through an adhesion based mechanism, to aid in pathogen clearance and then these platelets re-enter the general systemic circulation. Thus, a mechanism has been identified that relates liver inflammation to possible changes in the systemic circulation. However, the role that Kupffer cells play in cardiovascular disease initiation/progression has not been elucidated. Thus, our objective was to determine whether or not Kupffer cells are responsive to a classical cardiovascular risk factor and if these changes can be transmitted into the general systemic circulation. If Kupffer cells initiate inflammatory responses after exposure to classical cardiovascular risk factors, then this provides a potential alternative/synergistic pathway for cardiovascular disease initiation. We aimed to elucidate the prevalence of this potential pathway. We hypothesized that Kupffer cells would initiate a robust inflammatory response after exposure to tobacco cigarette or e-cigarette products and that the inflammatory response would have the potential to antagonize other salient cells for cardiovascular disease progression. To test this, Kupffer cells were incubated with tobacco smoke extracts, e-cigarette vapor extracts or pure nicotine. Complement deposition onto Kupffer cells, Kupffer cell complement receptor expression, oxidative stress production, cytokine release and viability and density were assessed after the exposure. We observed a robust inflammatory response, oxidative stress production and cytokine release after Kupffer cells were exposed to tobacco or e-cigarette extracts. We also observed a marginal decrease in cell viability coupled with a significant decrease in cell density. In general, this was not a function of the extract formulation (e.g. tobacco vs. e

  4. Pro-inflammatory activated Kupffer cells by lipids induce hepatic NKT cells deficiency through activation-induced cell death.

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    Tongfang Tang

    Full Text Available BACKGROUND: Dietary lipids play an important role in the progression of non-alcoholic fatty liver disease (NAFLD through alternation of liver innate immune response. AIMS: The present study was to investigate the effect of lipid on Kupffer cells phenotype and function in vivo and in vitro. And further to investigate the impact of lipid on ability of Kupffer cell lipid antigen presentation to activate NKT cells. METHODS: Wild type male C57BL/6 mice were fed either normal or high-fat diet. Hepatic steatosis, Kupffer cell abundance, NKT cell number and cytokine gene expression were evaluated. Antigen presentation assay was performed with Kupffer cells treated with certain fatty acids in vitro and co-cultured with NKT cells. RESULTS: High-fat diet induced hepatosteatosis, significantly increased Kupffer cells and decreased hepatic NKT cells. Lipid treatment in vivo or in vitro induced increase of pro-inflammatory cytokines gene expression and toll-like receptor 4 (TLR4 expression in Kupffer cells. Kupffer cells expressed high levels of CD1d on cell surface and only presented exogenous lipid antigen to activate NKT cells. Ability of Kupffer cells to present antigen and activate NKT cells was enhanced after lipid treatment. In addition, pro-inflammatory activated Kupffer cells by lipid treatment induced hepatic NKT cells activation-induced apoptosis and necrosis. CONCLUSION: High-fat diet increase Kupffer cells number and induce their pro-inflammatory status. Pro-inflammatory activated Kupfffer cells by lipid promote hepatic NKT cell over-activation and cell death, which lead to further hepatic NKT cell deficiency in the development of NAFLD.

  5. Pro-inflammatory activated Kupffer cells by lipids induce hepatic NKT cells deficiency through activation-induced cell death.

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    Tang, Tongfang; Sui, Yongheng; Lian, Min; Li, Zhiping; Hua, Jing

    2013-01-01

    Dietary lipids play an important role in the progression of non-alcoholic fatty liver disease (NAFLD) through alternation of liver innate immune response. The present study was to investigate the effect of lipid on Kupffer cells phenotype and function in vivo and in vitro. And further to investigate the impact of lipid on ability of Kupffer cell lipid antigen presentation to activate NKT cells. Wild type male C57BL/6 mice were fed either normal or high-fat diet. Hepatic steatosis, Kupffer cell abundance, NKT cell number and cytokine gene expression were evaluated. Antigen presentation assay was performed with Kupffer cells treated with certain fatty acids in vitro and co-cultured with NKT cells. High-fat diet induced hepatosteatosis, significantly increased Kupffer cells and decreased hepatic NKT cells. Lipid treatment in vivo or in vitro induced increase of pro-inflammatory cytokines gene expression and toll-like receptor 4 (TLR4) expression in Kupffer cells. Kupffer cells expressed high levels of CD1d on cell surface and only presented exogenous lipid antigen to activate NKT cells. Ability of Kupffer cells to present antigen and activate NKT cells was enhanced after lipid treatment. In addition, pro-inflammatory activated Kupffer cells by lipid treatment induced hepatic NKT cells activation-induced apoptosis and necrosis. High-fat diet increase Kupffer cells number and induce their pro-inflammatory status. Pro-inflammatory activated Kupfffer cells by lipid promote hepatic NKT cell over-activation and cell death, which lead to further hepatic NKT cell deficiency in the development of NAFLD.

  6. Endocytosis of heat-denatured albumin by cultured rat Kupffer cells

    International Nuclear Information System (INIS)

    Brouwer, A.; Knook, D.L.

    1982-01-01

    Purified Kupffer cells were obtained by centrifugal elutriation of sinusoidal cells isolated by pronase treatment of the rat liver. The endocytosis of radioactively labeled heat-aggregated colloidal albumin (CA 125 I) was investigated in maintenance cultures of the purified Kupffer cells. The endocytic capacity of the cells was studied during 4 days of culture. Maximum uptake was observed after 24 hr of culture, with a gradual decline during the following days. When the uptake was measured after incubation with increasing concentrations of CA 125 I, a saturation effect was observed. This finding and the observed high rate of uptake are strong indications that receptor sites on the cell membrane are involved in the mechanism of endocytosis. The uptake of CA 125 I by Kupffer cells was inhibited by the metabolic inhibitors fluoride and antimycin A, indicating that endocytosis of CA 125 I is dependent on energy derived from both glycolysis and mitochondrial respiration. The mechanism of internalization may also require the action of microfilaments as well as intact microtubules, since both cytochalasin B and colchicine inhibited the uptake of CA 125 I. The intracellular degradation of CA 125 I by Kupffer cells was strongly inhibited by chloroquine but not by colchicine. The degradation of ingested CA 125 I occurred within the Kupffer cell lysosomes

  7. Kupffer cell ablation attenuates cyclooxygenase-2 expression after trauma and sepsis.

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    Keller, Steve A; Paxian, Marcus; Lee, Sun M; Clemens, Mark G; Huynh, Toan

    2005-03-01

    Prostaglandins, synthesized by cyclooxygenase (COX), play an important role in the pathophysiology of inflammation. Severe injuries result in immunosuppression, mediated, in part, by maladaptive changes in macrophages. Herein, we assessed Kupffer cell-mediated cyclooxygenase-2 (COX-2) expression on liver function and damage after trauma and sepsis. To ablate Kupffer cells, Sprague Dawley rats were treated with gadolinium chloride (GdCl3) 48 and 24 h before experimentation. Animals then underwent femur fracture (FFx) followed 48 h later by cecal ligation and puncture (CLP). Controls received sham operations. After 24 h, liver samples were obtained, and mRNA and protein expression were determined by PCR, Western blot, and immunohistochemistry. Indocyanine-Green (ICG) clearance and plasma alanine aminotransferase (ALT) levels were determined to assess liver function and damage, respectively. One-way analysis of variance (ANOVA) with Student-Newman-Keuls test was used to assess statistical significance. After CLP alone, FFx+CLP, and GdCl3+FFx+CLP, clearance of ICG decreased. Plasma ALT levels increased in parallel with severity of injury. Kupffer cell depletion attenuated the increased ALT levels after FFx+CLP. Femur fracture alone did not alter COX-2 protein compared with sham. By contrast, COX-2 protein increased after CLP and was potentiated by sequential stress. Again, Kupffer cell depletion abrogated the increase in COX-2 after sequential stress. Immunohistochemical data confirmed COX-2 positive cells to be Kupffer cells. In this study, sequential stress increased hepatic COX-2 protein. Depletion of Kupffer cells reduced COX-2 and attenuated hepatocellular injuries. Our data suggest that Kupffer cell-dependent pathways may contribute to the inflammatory response leading to increased mortality after sequential stress.

  8. Kupffer cell complement receptor clearance function and host defense.

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    Loegering, D J

    1986-01-01

    Kupffer cells are well known to be important for normal host defense function. The development of methods to evaluate the in vivo function of specific receptors on Kupffer cells has made it possible to assess the role of these receptors in host defense. The rationale for studying complement receptors is based on the proposed important role of these receptors in host defense and on the observation that the hereditary deficiency of a complement receptor is associated with recurrent severe bacterial infections. The studies reviewed here demonstrate that forms of injury that are associated with depressed host defense including thermal injury, hemorrhagic shock, trauma, and surgery also cause a decrease in complement receptor clearance function. This decrease in Kupffer cell receptor clearance function was shown not to be the result of depressed hepatic blood flow or depletion of complement components. Complement receptor function was also depressed following the phagocytosis of particulates that are known to depress Kupffer cell host defense function. Endotoxemia and bacteremia also were associated with a depression of complement receptor function. Complement receptor function was experimentally depressed in uninjured animals by the phagocytosis of IgG-coated erythrocytes. There was a close association between the depression of complement receptor clearance function and increased susceptibility to the lethal effects of endotoxin and bacterial infection. These studies support the hypotheses that complement receptors on Kupffer cells are important for normal host defense and that depression of the function of these receptors impairs host defense.

  9. Ferritin expression in rat hepatocytes and Kupffer cells after lead nitrate treatment.

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    Fan, Yang; Yamada, Toshiyuki; Shimizu, Takeshi; Nanashima, Naoki; Akita, Miki; Suto, Kohji; Tsuchida, Shigeki

    2009-02-01

    Lead nitrate induces hepatocyte proliferation and subsequent apoptosis in rat livers. Iron is a constituent of heme and is also required for cell proliferation. In this study, the expression of ferritin light-chain (FTL), the major iron storage protein, was investigated in rat livers after a single intravenous injection of lead nitrate. Western blotting and immunohistochemistry revealed that FTL was increased in hepatocytes around the central veins and strongly expressed in nonparenchymal cells. Some FTL-positive nonparenchymal cells were identified as Kupffer cells that were positive for CD68. FTL-positive Kupffer cells occupied about 60% of CD68-positive cells in the periportal and perivenous areas. The relationships between FTL expression and apoptosis induction or the engulfment of apoptotic cells were examined. TUNEL-positive cells were increased in the treatment group, and enhanced expression of milk fat globule EGF-like 8 was demonstrated in some Kupffer cells and hepatocytes, indicating enhanced apoptosis induction and phagocytosis of apoptotic cells. FTL-positive Kupffer cells were not detected without lead nitrate treatment or in rat livers treated with clofibrate, which induces hepatocyte proliferation but not apoptosis. These results suggest that FTL expression in Kupffer cells after lead treatment is dependent on phagocytosis of apoptotic cells.

  10. Isoferritins in rat Kupffer cells, hepatocytes, and extrahepatic macrophages. Biosynthesis in cell suspensions and cultures in response to iron

    International Nuclear Information System (INIS)

    Doolittle, R.L.; Richter, G.W.

    1981-01-01

    Cultures of Kupffer cells and of hepatocytes, prepared from single rat livers, synthesized ferritin protein equally efficiently. In culture but not in suspension, both sorts of cells responded significantly to stimulation with iron by increased ferritin synthesis. As determined by isoelectric focusing, the isoferritin profiles of newly synthesized 14 -labeled Kupffer cell and hepatocyte ferritin were identical, each having three bands. However, unlabeled ferritin, extracted from nonparenchymal liver cells (mainly Kupffer and endothelial cells) of iron-loaded rats, contained an acidic isoferritin that was not present in hepatocyte ferritin. Investigation of ferritin synthesis in cultured peritoneal and alveolar macrophages yielded similar results. The isofocusing profile of newly synthesized peritoneal macrophage ferritin was indistinguishable from the profile of fresh Kupffer cell or hepatocyte ferritin. Thus, the three isoferritins common to Kupffer cells, hepatocytes, and extrahepatic macrophages are neither cell- nor tissue-specific. However, modifications on intracellular storage may affect the isofocusing properties. The findings, although consistent with the LnH24-n subunit model of ferritin protein, indicate identical restrictive genomic control of the H:L ratios in these sorts of cells. Further, they make it probable that Kupffer cell ferritin iron, originating by endogenous synthesis, is the principal source of Kupffer cell hemosiderin iron

  11. Superoxide produced by Kupffer cells is an essential effector in concanavalin A-induced hepatitis in mice.

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    Nakashima, Hiroyuki; Kinoshita, Manabu; Nakashima, Masahiro; Habu, Yoshiko; Shono, Satoshi; Uchida, Takefumi; Shinomiya, Nariyoshi; Seki, Shuhji

    2008-12-01

    Although concanavalin A (Con-A)-induced experimental hepatitis is thought to be induced by activated T cells, natural killer T (NKT) cells, and cytokines, precise mechanisms are still unknown. In the current study, we investigated the roles of Kupffer cells, NKT cells, FasL, tumor necrosis factor (TNF), and superoxide in Con-A hepatitis in C57BL/6 mice. Removal of Kupffer cells using gadolinium chloride (GdCl(3)) from the liver completely inhibited Con-A hepatitis, whereas increased serum TNF and IFN-gamma levels were not inhibited at all. Unexpectedly, anti-FasL antibody pretreatment did not inhibit Con-A hepatitis, whereas it inhibited hepatic injury induced by a synthetic ligand of NKT cells, alpha-galactosylceramide. Furthermore, GdCl(3) pretreatment changed neither the activation-induced down-regulation of NK1.1 antigens as well as T cell receptors of NKT cells nor the increased expression of the CD69 activation antigen of hepatic T cells. CD68(+) Kupffer cells greatly increased in proportion in the early phase after Con-A injection; this increase was abrogated by GdCl(3) pretreatment. Anti-TNF antibody (Ab) pretreatment did not inhibit the increase of Kupffer cells, but it effectively suppressed superoxide/reactive oxygen production from Kupffer cells and the resulting hepatic injury. Conversely, depletion of NKT cells in mice by NK1.1 Ab pretreatment did suppress both the increase of CD68(+) Kupffer cells and Con-A hepatitis. Consistently, the diminution of oxygen radicals produced by Kupffer cells by use of free radical scavengers greatly inhibited Con-A hepatitis without suppressing cytokine production. However, adoptive transfer experiments also indicate that a close interaction/cooperation of Kupffer cells with NKT cells is essential for Con-A hepatitis. Superoxide produced by Kupffer cells may be the essential effector in Con-A hepatitis, and TNF and NKT cells support their activation and superoxide production.

  12. Cross-activating invariant NKT cells and kupffer cells suppress cholestatic liver injury in a mouse model of biliary obstruction.

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    Caroline C Duwaerts

    Full Text Available Both Kupffer cells and invariant natural killer T (iNKT cells suppress neutrophil-dependent liver injury in a mouse model of biliary obstruction. We hypothesize that these roles are interdependent and require iNKT cell-Kupffer cell cross-activation. Female, wild-type and iNKT cell-deficient C57Bl/6 mice were injected with magnetic beads 3 days prior to bile duct ligation (BDL in order to facilitate subsequent Kupffer cell isolation. On day three post-BDL, the animals were euthanized and the livers dissected. Necrosis was scored; Kupffer cells were isolated and cell surface marker expression (flow cytometry, mRNA expression (qtPCR, nitric oxide (NO (. production (Griess reaction, and protein secretion (cytometric bead-array or ELISAs were determined. To address the potential role of NO (. in suppressing neutrophil accumulation, a group of WT mice received 1400W, a specific inducible nitric oxide synthase (iNOS inhibitor, prior to BDL. To clarify the mechanisms underlying Kupffer cell-iNKT cell cross-activation, WT animals were administered anti-IFN-γ or anti-lymphocyte function-associated antigen (LFA-1 antibody prior to BDL. Compared to their WT counterparts, Kupffer cells obtained from BDL iNKT cell-deficient mice expressed lower iNOS mRNA levels, produced less NO (. , and secreted more neutrophil chemoattractants. Both iNOS inhibition and IFN-γ neutralization increased neutrophil accumulation in the livers of BDL WT mice. Anti-LFA-1 pre-treatment reduced iNKT cell accumulation in these same animals. These data indicate that the LFA-1-dependent cross-activation of iNKT cells and Kupffer cells inhibits neutrophil accumulation and cholestatic liver injury.

  13. Demonstration of glucose-6-phosphate dehydrogenase in rat Kupffer cells by a newly-developed ultrastructural enzyme-cytochemistry

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    S Matsubara

    2009-06-01

    Full Text Available Although various tissue macrophages possess high glucose- 6-phosphate dehydrogenase (G6PD activity, which is reported to be closely associated with their phagocytotic/bactericidal function, the fine subcellular localization of this enzyme in liver resident macrophages (Kupffer cells has not been determined.We have investigated the subcellular localization of G6PD in Kupffer cells in rat liver, using a newly developed enzyme-cytochemical (copper-ferrocyanide method. Electron-dense precipitates indicating G6PD activity were clearly visible in the cytoplasm and on the cytosolic side of the endoplasmic reticulum of Kupffer cells. Cytochemical controls ensured specific detection of the enzymatic activity. Rat Kupffer cells abundantly possessed enzyme-cytochemically detectable G6PD activity. Kupffer cell G6PD may play a role in liver defense by delivering NADPH to NADPH-dependent enzymes. G6PD enzyme-cytochemistry may be a useful tool for the study of Kupffer cell functions.

  14. Isolation of Kupffer Cells and Hepatocytes from a Single Mouse Liver

    DEFF Research Database (Denmark)

    Aparicio-Vergara, Marcela; Tencerova, Michaela; Morgantini, Cecilia

    2017-01-01

    Liver perfusion is a common technique used to isolate parenchymal and non-parenchymal liver cells for in vitro experiments. This method allows hepatic cells to be separated based on their size and weight, by centrifugation using a density gradient. To date, other methods allow the isolation of only...... one viable hepatic cellular fraction from a single mouse; either parenchymal (hepatocytes) or non-parenchymal cells (i.e., Kupffer cells or hepatic stellate cells). Here, we describe a method to isolate both hepatocytes and Kupffer cells from a single mouse liver, thereby providing the unique...... advantage of studying different liver cell types that have been isolated from the same organism....

  15. Influence of Kupffer cell inactivation on cycloheximide-induced hepatic injury

    International Nuclear Information System (INIS)

    Kumagai, Kazuyoshi; Kiyosawa, Naoki; Ito, Kazumi; Yamoto, Takashi; Teranishi, Munehiro; Nakayama, Hiroyuki; Manabe, Sunao

    2007-01-01

    In our previous study, we found that cycloheximide (CHX) induces hepatocellular necrosis as well as hepatocellular apoptosis. This article evaluates the role of Kupffer cells on cycloheximide-induced hepatic injury using gadolinium chloride (GdCl 3 ) for the inhibition of Kupffer cells. One group of rats was treated with CHX (CHX group), and another was treated with GdCl 3 before being treated with the same dose of CHX (GdCl 3 /CHX group). The necrotic change in the GdCl 3 /CHX group was exacerbated under the induction of hepatocellular apoptosis by the CHX treatment. A substantial diminution of the number of ED1- or ED2-positive cells was demonstrated in the GdCl 3 /CHX group compared to the CHX group. In addition, the degree of decrease in ED2-positive cells was more apparent than that in ED1-positive cells. Increases in the mRNA levels of IL-10 and Stat3 were observed in the CHX group, but not in the GdCl 3 /CHX group. On the other hand, the hepatic mRNA levels of chemokines and adhesion molecules such as Ccl20, LOX-1, and E-selectin were significantly increased only in the GdCl 3 /CHX group. Thus, Kupffer cell inactivation by the GdCl 3 treatment leads to a loss of the capacity to produce IL-10, supposedly resulting in the enhancement of pro-inflammatory cytokine activities such as tumor necrosis factor (TNF) signaling. These events are suggested to be a factor of the inflammatory exacerbation in the livers of the GdCl 3 /CHX group. In conclusion, Kupffer cells may play a role in protecting hepatic necroinflammatory changes by releasing anti-inflammatory cytokines following the hepatocellular apoptosis resulting from CHX treatment

  16. Effect of allyl alcohol on hepatic transporter expression: Zonal patterns of expression and role of Kupffer cell function

    International Nuclear Information System (INIS)

    Campion, Sarah N.; Tatis-Rios, Cristina; Augustine, Lisa M.; Goedken, Michael J.; Rooijen, Nico van; Cherrington, Nathan J.; Manautou, Jose E.

    2009-01-01

    During APAP toxicity, activation of Kupffer cells is critical for protection from hepatotoxicity and up-regulation of multidrug resistance-associated protein 4 (Mrp4) in centrilobular hepatocytes. The present study was performed to determine the expression profile of uptake and efflux transporters in mouse liver following treatment with allyl alcohol (AlOH), a periportal hepatotoxicant. This study also investigated the role of Kupffer cells in AlOH hepatotoxicity, and whether changes in transport protein expression by AlOH are dependent on the presence of Kupffer cells. C57BL/6J mice received 0.1 ml clodronate liposomes to deplete Kupffer cells or empty liposomes 48 h prior to dosing with 60 mg/kg AlOH, i.p. Hepatotoxicity was assessed by plasma ALT and histopathology. Hepatic transporter mRNA and protein expression were determined by branched DNA signal amplification assay and Western blotting, respectively. Depletion of Kupffer cells by liposomal clodronate treatment resulted in heightened susceptibility to AlOH toxicity. Exposure to AlOH increased mRNA levels of several Mrp genes, while decreasing organic anion transporting polypeptides (Oatps) mRNA expression. Protein analysis mirrored many of these mRNA changes. The presence of Kupffer cells was not required for the observed changes in uptake and efflux transporters induced by AlOH. Immunofluorescent analysis revealed enhanced Mrp4 staining exclusively in centrilobular hepatocytes of AlOH treated mice. These findings demonstrate that Kupffer cells are protective from AlOH toxicity and that induction of Mrp4 occurs in liver regions away from areas of AlOH damage independent of Kupffer cell function. These results suggest that Kupffer cell mediators do not play a role in mediating centrilobular Mrp4 induction in response to periportal damage by AlOH

  17. Age-related changes in the endocytic capacity of rat liver Kupffer and endothelial cells

    International Nuclear Information System (INIS)

    Brouwer, A.; Barelds, R.J.; Knook, D.L.

    1985-01-01

    There are many indications that the functional capacity of the reticuloendothelial system (RES) declines with age. The aim of this study was to investigate the cellular basis of age-related changes in the clearance function of the RES. The experiments were focused mainly on Kupffer and endothelial cells of the liver which represent a major part of the RES and are primarily responsible for clearance of colloidal material from the circulation. The clearance capacity of the RES was tested clinically and experimentally by intravenous injection of colloids, such as radiolabeled heat-aggregated colloidal albumin. Age-related changes in the endocytosis of 125 I-labeled colloidal albumin (CA) in rats were determined by clearance and organ distribution of different doses of intravenously injected CA, uptake of CA by Kupffer and endothelial liver cells in vivo as determined after isolation of the cells from injected rats and kinetic studies on CA uptake by Kupffer cells in culture. The results show that, at a low dose, the clearance of CA is primarily determined by liver blood flow. At a higher saturating dose, plasma clearance and uptake by the liver are not significantly decreased with age. Endocytosis by endothelial cells, which accounts for about 60% of that of the whole liver, is also unchanged with age. In contrast, a significant decrease in endocytic capacity was observed for Kupffer cells in vivo. This age-related functional decline was also observed in Kupffer cells which were isolated from rats of different ages and maintained in culture

  18. Kupffer cells promote hepatic steatosis via interleukin-1-dependent suppression of peroxisome proliferator-activated receptor activity

    NARCIS (Netherlands)

    Stienstra, R.; Saudale, F.; Duval, C.N.C.; Keshtkar, S.; Groener, C.; Rooijen, van N.; Staels, B.; Kersten, A.H.; Müller, M.R.

    2010-01-01

    Kupffer cells have been implicated in the pathogenesis of various liver diseases. However, their involvement in metabolic disorders of the liver, including fatty liver disease, remains unclear. The present study sought to determine the impact of Kupffer cells on hepatic triglyceride storage and to

  19. Fibronectin and Kupffer cell function in fulminant hepatic failure

    International Nuclear Information System (INIS)

    Imawari, M.; Hughes, R.D.; Gove, C.D.; Williams, R.

    1985-01-01

    The relationship between plasma fibronectin, in vitro plasma opsonic activity, which measures the biological activity of fibronectin, and in vivo Kupffer cell function, as assessed by the systemic clearance of microaggregated [ 125 I]albumin, were determined simultaneously in 15 patients with fulminant hepatic failure and 12 normal subjects. Both the plasma fibronectin and plasma opsonic activity were significantly reduced in patients with fulminant hepatic failure, while the systemic clearance of microaggregated albumin was decreased. There was a significant correlation between plasma fibronectin and the plasma opsonic activity on admission, but no correlation could be detected between either parameter and the clearance of microaggregated albumin. A gelatin-derived plasma expander was shown to block the plasma opsonic activity both in vitro and in vivo. The low plasma fibronectin and decreased clearance of microaggregated albumin in fulminant hepatic failure reflect different aspects of the overall impairment of Kupffer cell function

  20. Hepatocellular proliferation in response to agonists of peroxisome proliferator-activated receptor alpha: a role for kupffer cells?

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    Cunningham Michael

    2006-01-01

    Full Text Available Abstract Background It has been proposed that PPARα agonists stimulate Kupffer cells in rodents which in turn, release mitogenic factors leading to hepatic hyperplasia, and eventually cancer. However, Kupffer cells do not express PPARα receptors, and PPARα agonists stimulate hepatocellular proliferation in both TNFα- and TNFα receptor-null mice, casting doubt on the involvement of Kupffer cells in the mitogenic response to PPARα agonists. This study was therefore designed to investigate whether the PPARα agonist PFOA and the Kupffer cell inhibitor methylpalmitate produce opposing effects on hepatocellular proliferation and Kupffer cell activity in vivo, in a manner that would implicate these cells in the mitogenic effects of PPARα agonists. Methods Male Sprague-Dawley rats were treated intravenously via the tail vein with methylpalmitate 24 hrs prior to perfluorooctanoic acid (PFOA, and were sacrificed 24 hrs later, one hr after an intraperitoneal injection of bromodeoxyuridine (BrdU. Sera were analyzed for TNFα and IL-1β. Liver sections were stained immunohistochemically and quantified for BrdU incorporated into DNA. Results Data show that PFOA remarkably stimulated hepatocellular proliferation in the absence of significant changes in the serum levels of either TNFα or IL-1β. In addition, methylpalmitate did not alter the levels of these mitogens in PFOA-treated animals, despite the fact that it significantly blocked the hepatocellular proliferative effect of PFOA. Correlation between hepatocellular proliferation and serum levels of TNFα or IL-1β was extremely poor. Conclusion It is unlikely that mechanisms involving Kupffer cells play an eminent role in the hepatic hyperplasia, and consequently hepatocarcinogenicity attributed to PPARα agonists. This conclusion is based on the above mentioned published data and the current findings showing animals treated with PFOA alone or in combination with methylpalmitate to have similar

  1. Kupffer cell blockade prevents rejection of human insulinoma cell xenograft in rats

    International Nuclear Information System (INIS)

    Lazar, G. Jr.; Farkas, G.; Lazar, G.

    1998-01-01

    Alloantigens are recognized by T-cells in the context of both class I and class II antigen, but class II antigens predominate in the recognition of xenoantigens. Since class II molecules bind peptides derived from exogenous proteins that have been phagocytized and digested into small fragments by antigen presenting cells, in the present studies the effect of gadolinium chloride (GdCl 3 )-induced Kupffer cell blockade on the survival of discordant insulinoma cell xenografts was investigated. Insulinoma cells isolated by means of collagenase from human insulinoma and cultured were transplanted through the v. portae into the liver of streptozotocin-induced diabetic, male, CFY inbred rats. In the control, streptozotocin-treated rats, the decrease in blood glucose level was only transitory, in contrast with the GdCl 3 -pretreated diabetic rats, which remained normoglycaemic during the 2-week observation period. Histologically, in the liver and lung of rats pre-treated with GdCl 3 , large areas of extensively proliferating insulinoma cells were seen, whereas no insulinoma cells were seen in either the liver or the lung of diabetic-control rats, not-treated with GdCl 3 . These studies suggest that the Kupffer cells play significant roles in the recognition of xenoantigens and the induction of xenograft rejection. (orig.)

  2. Kupffer cells are activated in cirrhotic portal hypertension and not normalised by TIPS

    DEFF Research Database (Denmark)

    Holland-Fischer, Peter; Grønbæk, Henning; Sandahl, Thomas Damgaard

    2011-01-01

    INTRODUCTION: Hepatic macrophages (Kupffer cells) undergo inflammatory activation during the development of portal hypertension in experimental cirrhosis; this activation may play a pathogenic role or be an epiphenomenon. Our objective was to study serum soluble CD163 (sCD163), a sensitive marker...... in the patients (52.2 vs 30.4 μg/l, pportal hypertension. The activation was not alleviated by the mechanical...... reduction of portal hypertension and the decreasing signs of endotoxinaemia. The findings suggest that Kupffer cell activation is a constitutive event that may play a pathogenic role for portal hypertension....

  3. Establishment of c-myc-immortalized Kupffer cell line from a C57BL/6 mouse strain

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    Hiroshi Kitani

    2014-01-01

    Full Text Available We recently demonstrated in several mammalian species, a novel procedure to obtain liver-macrophages (Kupffer cells in sufficient numbers and purity using a mixed primary culture of hepatocytes. In this study, we applied this method to the C57BL/6 mouse liver and established an immortalized Kupffer cell line from this mouse strain. The hepatocytes from the C57BL/6 adult mouse liver were isolated by a two-step collagenase perfusion method and cultured in T25 culture flasks. Similar to our previous studies, the mouse hepatocytes progressively changed their morphology into a fibroblastic appearance after a few days of culture. After 7–10 days of culture, Kupffer-like cells, which were contaminants in the hepatocyte fraction at the start of the culture, actively proliferated on the mixed fibroblastic cell sheet. At this stage, a retroviral vector containing the human c-myc oncogene and neomycin resistance gene was introduced into the mixed culture. Gentle shaking of the culture flask, followed by the transfer and brief incubation of the culture supernatant, resulted in a quick and selective adhesion of Kupffer cells to a plastic dish surface. After selection with G418 and cloning by limiting dilutions, a clonal cell line (KUP5 was established. KUP5 cells displayed typical macrophage morphology and were stably passaged at 4–5 days intervals for more than 5 months, with a population doubling time of 19 h. KUP5 cells are immunocytochemically positive for mouse macrophage markers, such as Mac-1, F4/80. KUP5 cells exhibited substantial phagocytosis of polystyrene microbeads and the release of inflammatory cytokines upon lipopolysaccharide stimulation. Taken together, KUP5 cells provide a useful means to study the function of Kupffer cells in vitro.

  4. Immunomodulation by gadolinium chloride-induced Kupffer cell phagocytosis blockade

    International Nuclear Information System (INIS)

    Lazar, G.; Husztik, E.; Kiss, I.; Szakacs, J.; Olah, J.

    1998-01-01

    Gadolinium chloride (GdCl 3 ), a rare earth metal salt, depresses macrophage activity, and is commonly used to study the physiology of the reticuloendothelial system. In the present work, the effect of GdCl 3 -induced Kupffer cell blockade on the humoral immune response in mice to sheep red blood cells (SRBC) was investigated. Kupffer cell phagocytosis blockade was found to increase both the primary and secondary immune responses to SRBC. The primary immune response was significantly augmented in animals injected intravenously with GdCl 3 2, 3 or 4 days before injection of the cellular antigen, but GdCl 3 injected 7 days before the antigen did not modify the immune response. Increased secondary humoral immune responses were also observed. When GdCl 3 was injected 2 days before the second dose of antigen, the numbers of both IgM and IgG-producing plaque forming cells were augmented. GdCl 3 injected 2 days before the first dose of SRBC did not modify the humoral immune response. Earlier studies with 51 Cr-labelled foreign red blood cells suggested that the augmentation of the humoral immune response in GdCl 3 -pretreated mice is a consequence of the spillover of the antigen from the liver into the spleen and other extrahepatic reticuloendothelial organs. (orig.)

  5. Role of Kupffer Cells in Thioacetamide-Induced Cell Cycle Dysfunction

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    Mirandeli Bautista

    2011-09-01

    Full Text Available It is well known that gadolinium chloride (GD attenuates drug-induced hepatotoxicity by selectively inactivating Kupffer cells. In the present study the effect of GD in reference to cell cycle and postnecrotic liver regeneration induced by thioacetamide (TA in rats was studied. Two months male rats, intraveously pretreated with a single dose of GD (0.1 mmol/Kg, were intraperitoneally injected with TA (6.6 mmol/Kg. Samples of blood and liver were obtained from rats at 0, 12, 24, 48, 72 and 96 h following TA intoxication. Parameters related to liver damage were determined in blood. In order to evaluate the mechanisms involved in the post-necrotic regenerative state, the levels of cyclin D and cyclin E as well as protein p27 and Proliferating Cell Nuclear Antigen (PCNA were determined in liver extracts because of their roles in the control of cell cycle check-points. The results showed that GD significantly reduced the extent of necrosis. Noticeable changes were detected in the levels of cyclin D1, cyclin E, p27 and PCNA when compared to those induced by thioacetamide. Thus GD pre-treatment reduced TA-induced liver injury and accelerated the postnecrotic liver regeneration. These results demonstrate that Kupffer cells are involved in TA-induced liver and also in the postnecrotic proliferative liver states.

  6. Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity

    NARCIS (Netherlands)

    Stienstra, Rinke; Saudale, Fredy; Duval, Caroline; Keshtkar, Shohreh; Groener, Johanna E. M.; van Rooijen, Nico; Staels, Bart; Kersten, Sander; Müller, Michael

    2010-01-01

    Kupffer cells have been implicated in the pathogenesis of various liver diseases. However, their involvement in metabolic disorders of the liver, including fatty liver disease, remains unclear. The present study sought to determine the impact of Kupffer cells on hepatic triglyceride storage and to

  7. Non-invasive imaging of kupffer cell status using radiolabelled mannosylated albumin

    NARCIS (Netherlands)

    Mahajan, V.; Hartimath, S.; Comley, R.; Stefan-Gueldner, M.; Roth, A.; Poelstra, K.; Reker-Smit, C.; Kamps, J.; Dierckx, R.; de Vries, Erik

    2014-01-01

    Background and Aims: Kupffer cells are responsible for maintaining liver homeostasis and have a vital role in chronic hepatotoxicity and various liver diseases. Positron Imaging Tomography (PET) is a non-invasive imaging technique that allows quantification and visualization of biochemical processes

  8. GPBAR1/TGR5 mediates bile acid-induced cytokine expression in murine Kupffer cells.

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    Guiyu Lou

    Full Text Available GPBAR1/TGR5 is a novel plasma membrane-bound G protein-coupled bile acid (BA receptor. BAs are known to induce the expression of inflammatory cytokines in the liver with unknown mechanism. Here we show that without other external stimuli, TGR5 activation alone induced the expression of interleukin 1β (IL-1β and tumor necrosis factor-α (TNF-α in murine macrophage cell line RAW264.7 or murine Kupffer cells. The TGR5-mediated increase of pro-inflammatory cytokine expression was suppressed by JNK inhibition. Moreover, the induced pro-inflammatory cytokine expression in mouse liver by 1% cholic acid (CA diet was blunted in JNK-/- mice. TGR5 activation by its ligands enhanced the phosphorylation levels, DNA-binding and trans-activities of c-Jun and ATF2 transcription factors. Finally, the induced pro-inflammatory cytokine expression in Kupffer cells by TGR5 activation correlated with the suppression of Cholesterol 7α-hydroxylase (Cyp7a1 expression in murine hepatocytes. These results suggest that TGR5 mediates the BA-induced pro-inflammatory cytokine production in murine Kupffer cells through JNK-dependent pathway. This novel role of TGR5 may correlate to the suppression of Cyp7a1 expression in hepatocytes and contribute to the delicate BA feedback regulation.

  9. Fumonisin B1 hepatotoxicity in mice is attenuated by depletion of Kupffer cells by gadolinium chloride

    International Nuclear Information System (INIS)

    He, Quanren; Kim, Jiyoung; Sharma, Raghubir P.

    2005-01-01

    Fumonisin B 1 (FB 1 ) is a toxic and carcinogenic mycotoxin produced by Fusarium verticillioides found on corn worldwide. The biological effects of FB 1 are attributed to sphingolipid metabolism disruption as a result of ceramide synthase inhibition. Tumor necrosis factor α (TNFα) is an important modulator of FB 1 hepatotoxicity. Kupffer cells are major source of cytokine production in liver. In the present study we investigated the effects of Kupffer cell depletion by gadolinium on FB 1 hepatotoxicity in female BALB/c mice. Mice were given saline or 50 mg/kg of gadolinium chloride once via the tail vein; 16 h later they were treated with subcutaneous injections of vehicle or 2.25 mg/kg/day FB 1 in saline for three successive days. Gadolinium significantly attenuated FB 1 -induced increases in the activities of circulating alanine aminotransferase and aspartate aminotransferase and reduced the FB 1 -induced hepatocyte apoptosis and free sphinganine accumulation in liver. Both gadolinium and FB 1 treatments individually increased the expression of selected cell signal factors; e.g., TNFα, TNF receptor 1, TNF-related apoptosis-inducing ligand, lymphotoxin β, interferon γ, and transforming growth factor β1; gadolinium chloride did not alter FB 1 -induced expression of the above genes. Results indicated that Kupffer cells play a role in FB 1 hepatotoxicity. Decreased FB 1 -induced sphinganine accumulation and increased protective TNFα signaling by gadolinium chloride may in part account for its ameliorating effect on FB 1 liver damage

  10. Kupffer cells are activated in cirrhotic portal hypertension and not normalised by TIPS.

    Science.gov (United States)

    Holland-Fischer, Peter; Grønbæk, Henning; Sandahl, Thomas Damgaard; Moestrup, Søren K; Riggio, Oliviero; Ridola, Lorenzo; Aagaard, Niels Kristian; Møller, Holger Jon; Vilstrup, Hendrik

    2011-10-01

    Hepatic macrophages (Kupffer cells) undergo inflammatory activation during the development of portal hypertension in experimental cirrhosis; this activation may play a pathogenic role or be an epiphenomenon. Our objective was to study serum soluble CD163 (sCD163), a sensitive marker of macrophage activation, before and after reduction of portal venous pressure gradient by insertion of a transjugular intrahepatic portosystemic shunt (TIPS) in patients with cirrhosis. sCD163 was measured in 11 controls and 36 patients before and 1, 4 and 26 weeks after TIPS. We used lipopolysaccharide binding protein (LBP) levels as a marker of endotoxinaemia. Liver function and clinical status of the patients were assessed by galactose elimination capacity and Model for End Stage Liver Disease score. The sCD163 concentration was more than threefold higher in the patients than in the controls (median 5.22 mg/l vs 1.45 mg/l, pportal venous pressure gradient (r(2)=0.24, pportal vein (pportal hypertension. The activation was not alleviated by the mechanical reduction of portal hypertension and the decreasing signs of endotoxinaemia. The findings suggest that Kupffer cell activation is a constitutive event that may play a pathogenic role for portal hypertension.

  11. Can technetium-labelled millimicrospheres be used to measure Kupffer-cell function

    International Nuclear Information System (INIS)

    Pearson, H.J.; Chamberlain, J.; Anderson, J.; Bowry, V.; Bell, P.R.F.

    1985-01-01

    It has been suggested that sodium pertechnetate sup(99m)Tc millimicrospheres can be used to measure Kupffercell function. We studied animals and humans to show whether the clearance and catabolism of sup(99m)Tc-labelled millimicrospheres can be used as a measure of Kupffer-cell function. Comparison with albumin 125 I-microaggregates clearance of human serum albumin failed to demonstrate that they can be used for this purpose. We suggest that their blood clearance is mainly an expression of liver blood flow. (orig.)

  12. Fumonisin B{sub 1} hepatotoxicity in mice is attenuated by depletion of Kupffer cells by gadolinium chloride

    Energy Technology Data Exchange (ETDEWEB)

    He, Quanren [Department of Physiology and Pharmacology, College of Veterinary Medicine, The University of Georgia, Athens, GA 30602-7389 (United States); Kim, Jiyoung [Department of Physiology and Pharmacology, College of Veterinary Medicine, The University of Georgia, Athens, GA 30602-7389 (United States); Sharma, Raghubir P [Department of Physiology and Pharmacology, College of Veterinary Medicine, The University of Georgia, Athens, GA 30602-7389 (United States)

    2005-02-01

    Fumonisin B{sub 1} (FB{sub 1}) is a toxic and carcinogenic mycotoxin produced by Fusarium verticillioides found on corn worldwide. The biological effects of FB{sub 1} are attributed to sphingolipid metabolism disruption as a result of ceramide synthase inhibition. Tumor necrosis factor {alpha} (TNF{alpha}) is an important modulator of FB{sub 1} hepatotoxicity. Kupffer cells are major source of cytokine production in liver. In the present study we investigated the effects of Kupffer cell depletion by gadolinium on FB{sub 1} hepatotoxicity in female BALB/c mice. Mice were given saline or 50 mg/kg of gadolinium chloride once via the tail vein; 16 h later they were treated with subcutaneous injections of vehicle or 2.25 mg/kg/day FB{sub 1} in saline for three successive days. Gadolinium significantly attenuated FB{sub 1}-induced increases in the activities of circulating alanine aminotransferase and aspartate aminotransferase and reduced the FB{sub 1}-induced hepatocyte apoptosis and free sphinganine accumulation in liver. Both gadolinium and FB{sub 1} treatments individually increased the expression of selected cell signal factors; e.g., TNF{alpha}, TNF receptor 1, TNF-related apoptosis-inducing ligand, lymphotoxin {beta}, interferon {gamma}, and transforming growth factor {beta}1; gadolinium chloride did not alter FB{sub 1}-induced expression of the above genes. Results indicated that Kupffer cells play a role in FB{sub 1} hepatotoxicity. Decreased FB{sub 1}-induced sphinganine accumulation and increased protective TNF{alpha} signaling by gadolinium chloride may in part account for its ameliorating effect on FB{sub 1} liver damage.

  13. CD205-TLR9-IL-12 axis contributes to CpG-induced oversensitive liver injury in HBsAg transgenic mice by promoting the interaction of NKT cells with Kupffer cells.

    Science.gov (United States)

    Hou, Xin; Hao, Xiaolei; Zheng, Meijuan; Xu, Congfei; Wang, Jun; Zhou, Rongbin; Tian, Zhigang

    2017-08-01

    Gut-derived bacterial products contribute to liver inflammation and injury during chronic hepatitis B virus infection; however, the underlying mechanisms remain obscure. In this study, hepatitis B surface antigen transgenic (HBs-Tg) mice and their wild-type (WT) control C57BL/6 mice were injected with CpG-oligodeoxynucleotides (ODNs) to mimic the translocation of gut microbial products into the systemic circulation. We found that, compared with the WT mice, the HBs-Tg mice were oversensitive to CpG-ODN-induced liver injury, which was dependent on natural killer T (NKT) cells. CpG-ODN injection enhanced the expression of Fas ligand (FasL) on NKT cells. In addition, hepatocytes from the HBs-Tg mice expressed higher levels of Fas than did those from the WT mice, which was further augmented by CpG-ODN. Interaction of Fas and FasL was involved in the cytotoxicity of NKT cells against hepatocytes in the HBs-Tg mice. Moreover, Kupffer cells in the HBs-Tg mice expressed higher levels of CD205 and produced greater amounts of interleukin (IL)-12 than did those in the WT mice. Finally, the depletion of Kupffer cells, neutralization of IL-12 or specific silencing of CD205 on Kupffer cells significantly inhibited CpG-ODN-induced liver injury and NKT activation in the HBs-Tg mice. Our data suggest that CD205-expressing Kupffer cells respond to CpG-ODNs and subsequently release IL-12 to promote NKT cell activation. Activated NKT cells induce liver damage through the Fas signaling pathway in HBs-Tg mice.

  14. Thyroid Hormone-Induced Cytosol-to-Nuclear Translocation of Rat Liver Nrf2 Is Dependent on Kupffer Cell Functioning

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    Luis A. Videla

    2012-01-01

    Full Text Available L-3,3′,5-triiodothyronine (T3 administration upregulates nuclear factor-E2-related factor 2 (Nrf2 in rat liver, which is redox-sensitive transcription factor mediating cytoprotection. In this work, we studied the role of Kupffer cell respiratory burst activity, a process related to reactive oxygen species generation and liver homeostasis, in Nrf2 activation using the macrophage inactivator gadolinium chloride (GdCl3; 10 mg/kg i.v. 72 h before T3 [0.1 mg/kg i.p.] or NADPH oxidase inhibitor apocynin (1.5 mmol/L added to the drinking water for 7 days before T3, and determinations were performed 2 h after T3. T3 increased nuclear/cytosolic Nrf2 content ratio and levels of heme oxygenase 1 (HO-1, catalytic subunit of glutamate cysteine ligase, and thioredoxin (Western blot over control values, proteins whose gene transcription is induced by Nrf2. These changes were suppressed by GdCl3 treatment prior to T3, an agent-eliciting Kupffer-cell depletion, inhibition of colloidal carbon phagocytosis, and the associated respiratory burst activity, with enhancement in nuclear inhibitor of Nrf2 kelch-like ECH-associated protein 1 (Keap1/Nrf2 content ratios suggesting Nrf2 degradation. Under these conditions, T3-induced tumor necrosis factor-α (TNF-α response was eliminated by previous GdCl3 administration. Similar to GdCl3, apocynin given before T3 significantly reduced liver Nrf2 activation and HO-1 expression, a NADPH oxidase inhibitor eliciting abolishment of colloidal carbon-induced respiratory burst activity without altering carbon phagocytosis. It is concluded that Kupffer cell functioning is essential for upregulation of liver Nrf2-signaling pathway by T3. This contention is supported by suppression of the respiratory burst activity of Kupffer cells and the associated reactive oxygen species production by GdCl3 or apocynin given prior to T3, thus hindering Nrf2 activation.

  15. Activation of Kupffer Cells Is Associated with a Specific Dysbiosis Induced by Fructose or High Fat Diet in Mice.

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    Gladys Ferrere

    Full Text Available The increase consumption of fructose in diet is associated with liver inflammation. As a specific fructan substrate, fructose may modify the gut microbiota which is involved in obesity-induced liver disease. Here, we aimed to assess whether fructose-induced liver damage was associated with a specific dysbiosis, especially in mice fed a high fat diet (HFD. To this end, four groups of mice were fed with normal and HFD added or not with fructose. Body weight and glucose sensitivity, liver inflammation, dysbiosis and the phenotype of Kupffer cells were determined after 16 weeks of diet. Food intake was increased in the two groups of mice fed with the HFD. Mice fed with HFD and fructose showed a higher infiltration of lymphocytes into the liver and a lower inflammatory profile of Kupffer cells than mice fed with the HFD without fructose. The dysbiosis associated with diets showed that fructose specifically prevented the decrease of Mouse intestinal bacteria in HFD fed mice and increased Erysipelotrichi in mice fed with fructose, independently of the amount of fat. In conclusion, fructose, used as a sweetener, induced a dysbiosis which is different in presence of fat in the diet. Consequently, the activation of Kupffer cells involved in mice model of HFD-induced liver inflammation was not observed in an HFD/fructose combined diet. These data highlight that the complexity of diet composition could highly impact the development of liver lesions during obesity. Specific dysbiosis associated with the diet could explain that the progressions of liver damage are different.

  16. The cachectic mediator proteolysis inducing factor activates NF-kappaB and STAT3 in human Kupffer cells and monocytes

    NARCIS (Netherlands)

    Watchorn, T.M.; Dowidar, N.; Dejong, C.H.; Waddell, I.D.; Garden, O.J.; Ross, J.A.

    2005-01-01

    A novel proteoglycan, proteolysis inducing factor (PIF), is capable of inducing muscle proteolysis during the process of cancer cachexia, and of inducing an acute phase response in human hepatocytes. We investigated whether PIF is able to activate pro-inflammatory pathways in human Kupffer cells,

  17. Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis.

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    Giovanni Sitia

    2011-06-01

    Full Text Available Kupffer cells (KCs are widely considered important contributors to liver injury during viral hepatitis due to their pro-inflammatory activity. Herein we utilized hepatitis B virus (HBV-replication competent transgenic mice and wild-type mice infected with a hepatotropic adenovirus to demonstrate that KCs do not directly induce hepatocellular injury nor do they affect the pathogenic potential of virus-specific CD8 T cells. Instead, KCs limit the severity of liver immunopathology. Mechanistically, our results are most compatible with the hypothesis that KCs contain liver immunopathology by removing apoptotic hepatocytes in a manner largely dependent on scavenger receptors. Apoptotic hepatocytes not readily removed by KCs become secondarily necrotic and release high-mobility group box 1 (HMGB-1 protein, promoting organ infiltration by inflammatory cells, particularly neutrophils. Overall, these results indicate that KCs resolve rather than worsen liver immunopathology.

  18. Predominance of Th1 response, increase of megakaryocytes and Kupffer cells are related to survival in Trypanosoma cruzi infected mice treated with Lycopodium clavatum.

    Science.gov (United States)

    Falkowski-Temporini, Gislaine Janaina; Lopes, Carina Ribeiro; Massini, Paula Fernanda; Brustolin, Camila Fernanda; Sandri, Patricia Flora; Ferreira, Érika Cristina; Aleixo, Denise Lessa; Pala, Nelson Roberto; de Araújo, Silvana Marques

    2016-12-01

    We investigated the number of megakaryocytes, Kupffer cells and ratios of Th1/Th2 and Th1/Th17 cytokines in survival of mice infected with Y strain of Trypanosoma cruzi and treated with Lycopodium clavatum. In a blind, randomized and controlled assay, Swiss male mice, 8weeks-old, infected with 1400 trypomastigotes (Y strain) were divided into groups and treated with: GLy - Lycopodium clavatum dynamization13c and GCI - alcohol solution 7° GL (vehicle medicine). The treatment was offered two days before infection and on the 2nd, 4th and 6th days after infection, overnight (1mL/100mL) and ad libitum. Parameters assessed were: survival rate, number of megakaryocytes and Kupffer cells, cytokines dosage (TNF-α, IFN-γ, IL-2, IL-4, IL-6, IL-10, IL-17), Th1/Th2 and Th1/Th17 ratios. The increase in megakaryocytes, Kupffer cells, predominance of Th1 response, with increased TNF-α, IL-10, TNF-α/IL-4, TNF-α/IL-17 and decreased IL-6 IL-6/IL-4, are related to increased survival in mice infected with T. cruzi and treated with Lycopodium clavatum 13c. This result demonstrates the possibility of an alternative approach for the treatment of Chagas disease with dynamized drugs. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. Pivotal roles of Kupffer cells in the progression and regression of DDC-induced chronic cholangiopathy.

    Science.gov (United States)

    Jemail, Leila; Miyao, Masashi; Kotani, Hirokazu; Kawai, Chihiro; Minami, Hirozo; Abiru, Hitoshi; Tamaki, Keiji

    2018-04-23

    Kupffer cells (KCs) are key players in maintaining tissue homeostasis and are involved in various liver diseases. However, the roles of KCs in the pathogenesis of cholangiopathy are largely unknown. We aimed to investigate the precise roles of KCs in both the progression and regression phases of the 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC)-induced cholangiopathy model. In the early phase of DDC-induced cholangiopathy, the number of KCs significantly increased over time. Moreover, KCs were associated with abnormal phenotypic changes in other liver cells, such as hepatocytes, biliary epithelial cells, liver sinusoidal endothelial cells, and hepatic stellate cells. In contrast, KC depletion by clodronate administration suppressed the progression of the disease, and maintained the phenotypes of other cells. In the regression phase, the numbers of KCs significantly decreased, and the cells redifferentiated to their quiescent state. In contrast, KC depletion delayed the recovery of cells by maintaining other liver cells in an active state. These findings suggest that KCs play detrimental roles in the progression phase; however, they are beneficial in the regression phase by mediating interactions between other liver cells. Our data provide new insights into the roles of KCs in the pathogenesis of cholangiopathy.

  20. Failure to demonstrate a major role for Kupffer cells and radiosensitive leukocytes in immunoglobulin-mediated elimination of Trypanosoma musculi

    International Nuclear Information System (INIS)

    Kongshavn, P.A.; Shaw, K.; Ghadirian, E.; Ulczak, O.

    1990-01-01

    Previous studies have indicated that elimination of parasitemia in Trypanosoma musculi infection is brought about by immunoglobulin G2a antibodies, C3, and an effector cell. Experiments were designed to identify the putative effector cell by using several approaches. Infected C5-deficient or C5-sufficient mice treated with silica particles or given 900 rads of radiation 3 days earlier effectively eliminated trypanosomes following administration of immune plasma (IP). Silica-treated, noninfected mice given T. musculi preincubated with IP also cleared the parasites. Radiolabeling studies revealed that uptake of the cleared trypanosomes by the liver in normal mice was relatively low and fell only slightly (19%) in silica-treated mice. In contrast, uptake of radiolabeled sheep erythrocytes by the liver was normally much higher and fell drastically (7%) in silica-treated mice. Mice were then immunocompromised by 900 rads of radiation, silica particles, and anti-platelet serum combined before IP-sensitized trypanosomes were given. Leukocyte and platelet counts were both reduced by 95% and sheep erythrocyte uptake by the liver fell from 77 to 5%; however, greater than 99% of the injected trypanosomes were cleared in these mice and uptake of radiolabeled trypanosomes by the liver was similar to that of normal mice. Lastly, in anesthetized mice in which Kupffer cells were excluded surgically from the circulation, greater than 99% of the IP-sensitized trypanosomes disappeared rapidly from the blood. Only 7% of the radiolabel was found in the liver versus 60% in sham-operated mice. The results are interpreted as showing that hepatic Kupffer cells play a minor role in the immune elimination of T. musculi. Likewise, radiosensitive leukocytes and platelets are unlikely to be sole candidates for the putative effector cell that mediates a cure of murine trypanosomiasis

  1. Dynamic imaging of experimental Leishmania donovani-induced hepatic granulomas detects Kupffer cell-restricted antigen presentation to antigen-specific CD8 T cells.

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    Lynette Beattie

    2010-03-01

    Full Text Available Kupffer cells (KCs represent the major phagocytic population within the liver and provide an intracellular niche for the survival of a number of important human pathogens. Although KCs have been extensively studied in vitro, little is known of their in vivo response to infection and their capacity to directly interact with antigen-specific CD8(+ T cells. Here, using a combination of approaches including whole mount and thin section confocal microscopy, adoptive cell transfer and intra-vital 2-photon microscopy, we demonstrate that KCs represent the only detectable population of mononuclear phagocytes within granulomas induced by Leishmania donovani infection that are capable of presenting parasite-derived peptide to effector CD8(+ T cells. This restriction of antigen presentation to KCs within the Leishmania granuloma has important implications for the identification of new candidate vaccine antigens and for the design of novel immuno-therapeutic interventions.

  2. Gold nanoparticles administration induced prominent inflammatory, central vein intima disruption, fatty change and Kupffer cells hyperplasia

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    Abdelhalim Mohamed

    2011-08-01

    Full Text Available Abstract Background Advances in nanotechnology have identified promising candidates for many biological, biomedical and biomedicine applications. They are being increasingly exploited for medical uses and other industrial applications. The aim of the present study was to investigate the effects of administration of gold nanoparticles (GNPs on inflammatory cells infiltration, central vein intima disruption, fatty change, and Kupffer cells hyperplasia in the hepatic tissue in an attempt to cover and understand the toxicity and the potential threat of their therapeutic and diagnostic use. Methods A total of 70 healthy male Wistar-Kyoto rats were exposed to GNPs received 50 or 100 μl of GNPs infusion of 10, 20 and 50 nm GNPs for 3 or 7 days. Animals were randomly divided into groups, 12 GNPs-treated rats groups and one control group (NG. Groups 1, 2 and 3 received infusion of 50 μl GNPs of size 10 nm (3 or 7 days, size 20 nm (3 or 7 days and 50 nm (3 or 7 days, respectively; while groups 4, 5 and 6 received infusion of 100 μl GNPs of size 10 nm, size 20 nm and 50 nm, respectively. Results In comparison with respective control rats, exposure to GNPs doses has produced alterations in the hepatocytes, portal triads and sinusoids. The alterations in the hepatocytes were mainly vacuolar to hydropic degeneration, cytopasmic hyaline vacuolation, polymorphism, binucleation, karyopyknosis, karyolysis, karyorrhexis and necrosis. In addition, inflammatory cell infiltration, Kupffer cells hyperplasia, central veins intima disruption, hepatic strands dilatation and occasional fatty change together with a loss of normal architechiture of hepatic strands were also seen. Conclusions The alterations induced by the administration of GNPs were size-dependent with smaller ones induced more affects and related with time exposure of GNPs. These alterations might be an indication of injured hepatocytes due to GNPs toxicity that became unable to deal with the

  3. Soluble CD163, a marker of Kupffer cell activation, is related to portal hypertension in patients with liver cirrhosis

    DEFF Research Database (Denmark)

    Grønbaek, H; Sandahl, T D; Mortensen, C

    2012-01-01

    BACKGROUND: Activation of Kupffer cells may be involved in the pathogenesis of portal hypertension by release of vasoconstrictive substances and fibrosis due to co-activation of hepatic stellate cells. AIM: To study soluble plasma (s) CD163, a specific marker of activated macrophages......, as a biomarker for portal hypertension in patients with liver cirrhosis. METHODS: We measured sCD163 concentration and the hepatic venous pressure gradient (HVPG) by liver vein catheterisation in 81 cirrhosis patients (Child-Pugh CP-A: n = 26, CP-B: n = 29, CP-C: n = 26) and 22 healthy subjects. We also measured...... for HVPG. These findings support a primary role of macrophage activation in portal hypertension, and may indicate a target for biological intervention....

  4. Amphiphilic core shell nanoparticles containing dense polyethyleneimine shells for efficient delivery of microRNA to Kupffer cells

    Directory of Open Access Journals (Sweden)

    Liu Z

    2016-06-01

    Full Text Available Zuojin Liu,1,* Dechao Niu,2,3,* Junyong Zhang,1 Wenfeng Zhang,1 Yuan Yao,2 Pei Li,2 Jianping Gong1 1Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 2Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, 3Lab of Low-Dimensional Materials Chemistry, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, People’s Republic of China *These authors contributed equally to this work Abstract: Efficient and targeted delivery approach to transfer exogenous genes into macrophages is still a great challenge. Current gene delivery methods often result in low cellular uptake efficiency in vivo in some types of cells, especially for the Kupffer cells (KCs. In this article, we demonstrate that amphiphilic core–shell nanoparticles (NPs consisting of well-defined hydrophobic poly(methyl methacrylate (PMMA cores and branched polyethyleneimine (PEI shells (denoted as PEI@PMMA NPs are efficient nanocarriers to deliver microRNA (miRNA-loaded plasmid to the KCs. Average hydrodynamic diameter of PEI@PMMA NPs was 279 nm with a narrow size distribution. The NPs also possessed positive surface charges up to +30 mV in water, thus enabling effective condensation of negatively charged plasmid DNA. Gel electrophoresis assay showed that the resultant PEI@PMMA NPs were able to completely condense miRNA plasmid at a weight ratio of 25:1 (N/P ratio equal to 45:1. The Cell Counting Kit-8 assay and flow cytometry results showed that the PEI@PMMA/miRNA NPs displayed low cytotoxicity and cell apoptosis activity against the KCs. The maximum cell transfection efficiency reached 34.7% after 48 hours, which is much higher than that obtained by using the commercial Lipofectamine™ 2000 (1.7%. Bio-transmission electron microscope observation revealed that the PEI@PMMA NPs were mainly distributed in

  5. Mesenchymal stem cells improve mouse non-heart-beating liver graft survival by inhibiting Kupffer cell apoptosis via TLR4-ERK1/2-Fas/FasL-caspase3 pathway regulation

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    Yang Tian

    2016-10-01

    Full Text Available Abstract Background Liver transplantation is the optimal treatment option for end-stage liver disease, but organ shortages dramatically restrict its application. Donation after cardiac death (DCD is an alternative approach that may expand the donor pool, but it faces challenges such as graft dysfunction, early graft loss, and cholangiopathy. Moreover, DCD liver grafts are no longer eligible for transplantation after their warm ischaemic time exceeds 30 min. Mesenchymal stem cells (MSCs have been proposed as a promising therapy for treatment of certain liver diseases, but the role of MSCs in DCD liver graft function remains elusive. Methods In this study, we established an arterialized mouse non-heart-beating (NHB liver transplantation model, and compared survival rates, cytokine and chemokine expression, histology, and the results of in vitro co-culture experiments in animals with or without MSC infusion. Results MSCs markedly ameliorated NHB liver graft injury and improved survival post-transplantation. Additionally, MSCs suppressed Kupffer cell apoptosis, Th1/Th17 immune responses, chemokine expression, and inflammatory cell infiltration. In vitro, PGE2 secreted by MSCs inhibited Kupffer cell apoptosis via TLR4-ERK1/2-caspase3 pathway regulation. Conclusion Our study uncovers a protective role for MSCs and elucidates the underlying immunomodulatory mechanism in an NHB liver transplantation model. Our results suggest that MSCs are uniquely positioned for use in future clinical studies owing to their ability to protect DCD liver grafts, particularly in patients for whom DCD organs are not an option according to current criteria.

  6. Time course investigation of PPARα- and Kupffer cell-dependent effects of WY-14,643 in mouse liver using microarray gene expression

    International Nuclear Information System (INIS)

    Woods, Courtney G.; Kosyk, Oksana; Bradford, Blair U.; Ross, Pamela K.; Burns, Amanda M.; Cunningham, Michael L.; Qu Pingping; Ibrahim, Joseph G.; Rusyn, Ivan

    2007-01-01

    Administration of peroxisome proliferators to rodents causes proliferation of peroxisomes, induction of β-oxidation enzymes, hepatocellular hypertrophy and hyperplasia, with chronic exposure ultimately leading to hepatocellular carcinomas. Many responses associated with peroxisome proliferators are nuclear receptor-mediated events involving peroxisome proliferators-activated receptor alpha (PPARα). A role for nuclear receptor-independent events has also been shown, with evidence of Kupffer cell-mediated free radical production, presumably through NAPDH oxidase, induction of redox-sensitive transcription factors involved in cytokine production and cytokine-mediated cell replication following acute treatment with peroxisome proliferators in rodents. Recent studies have demonstrated, by using p47 phox -null mice which are deficient in NADPH oxidase, that this enzyme is not related to the phenotypic events caused by prolonged administration of peroxisome proliferators. In an effort to determine the timing of the transition from Kupffer cell-to PPARα-dependent modulation of peroxisome proliferator effects, gene expression was assessed in liver from Pparα-null, p47 phox -null and corresponding wild-type mice following treatment with 4-chloro-6-(2,3-xylidino)-pyrimidynylthioacetic acid (WY-14,643) for 8 h, 24 h, 72 h, 1 week or 4 weeks. WY-14,643-induced gene expression in p47 phox -null mouse liver differed substantially from wild-type mice at acute doses and striking differences in baseline expression of immune related genes were evident. Pathway mapping of genes that respond to WY-14,643 in a time- and dose-dependent manner demonstrates suppression of immune response, cell death and signal transduction and promotion of lipid metabolism, cell cycle and DNA repair. Furthermore, these pathways were largely dependent on PPARα, not NADPH oxidase demonstrating a temporal shift in response to peroxisome proliferators. Overall, this study shows that NADPH oxidase

  7. Histones activate the NLRP3 Inflammasome in Kupffer Cells during Sterile Inflammatory Liver Injury

    Science.gov (United States)

    Huang, Hai; Chen, Hui-Wei; Evankovich, John; Yan, Wei; Rosborough, Brian R.; Nace, Gary W.; Ding, Qing; Loughran, Patricia; Beer-Stolz, Donna; Billiar, Timothy R.; Esmon, Charles T.; Tsung, Allan

    2013-01-01

    Cellular processes that drive sterile inflammatory injury after hepatic ischemia/reperfusion (I/R) injury are not completely understood. Activation of the inflammasome plays a key role in response to invading intracellular pathogens, but mounting evidence suggests it also plays a role in inflammation driven by endogenous danger-associate molecular pattern (DAMP) molecules released after ischemic injury. The nucleotide-binding domain, leucine-rich repeat containing protein 3 (NLRP3) inflammasome is one such process, and the mechanism by which its activation results in damage and inflammatory responses following liver I/R is unknown. Here we report that both NLRP3 and its downstream target Caspase-1 are activated I/R and are essential for hepatic I/R injury as both NLRP3 and Caspase-1 KO mice are protected from injury. Furthermore, inflammasome-mediated injury is dependent on Caspase-1 expression in liver non-parenchymal cells. While upstream signals that activate the inflammasome during ischemic injury are not well characterized, we show that endogenous extracellular histones activate the NLRP3 inflammasome during liver I/R through Toll-like Receptor-9 (TLR9). This occurs through TLR9-dependent generation of reactive oxygen species. This mechanism is operant in resident liver Kupffer cells, which drive innate immune responses after I/R injury by recruiting additional cell types, including neutrophils and inflammatory monocytes. These novel findings illustrate a new mechanism by which extracellular histones and activation of NLRP3 inflammasome contribute to liver damage and activation of innate immunity during sterile inflammation. PMID:23904166

  8. Klf8 regulates left-right asymmetric patterning through modulation of Kupffer's vesicle morphogenesis and spaw expression.

    Science.gov (United States)

    Lin, Che-Yi; Tsai, Ming-Yuan; Liu, Yu-Hsiu; Lu, Yu-Fen; Chen, Yi-Chung; Lai, Yun-Ren; Liao, Hsin-Chi; Lien, Huang-Wei; Yang, Chung-Hsiang; Huang, Chang-Jen; Hwang, Sheng-Ping L

    2017-07-17

    Although vertebrates are bilaterally symmetric organisms, their internal organs are distributed asymmetrically along a left-right axis. Disruption of left-right axis asymmetric patterning often occurs in human genetic disorders. In zebrafish embryos, Kupffer's vesicle, like the mouse node, breaks symmetry by inducing asymmetric expression of the Nodal-related gene, spaw, in the left lateral plate mesoderm (LPM). Spaw then stimulates transcription of itself and downstream genes, including lft1, lft2, and pitx2, specifically in the left side of the diencephalon, heart and LPM. This developmental step is essential to establish subsequent asymmetric organ positioning. In this study, we evaluated the role of krüppel-like factor 8 (klf8) in regulating left-right asymmetric patterning in zebrafish embryos. Zebrafish klf8 expression was disrupted by both morpholino antisense oligomer-mediated knockdown and a CRISPR-Cas9 system. Whole-mount in situ hybridization was conducted to evaluate gene expression patterns of Nodal signalling components and the positions of heart and visceral organs. Dorsal forerunner cell number was evaluated in Tg(sox17:gfp) embryos and the length and number of cilia in Kupffer's vesicle were analyzed by immunocytochemistry using an acetylated tubulin antibody. Heart jogging, looping and visceral organ positioning were all defective in zebrafish klf8 morphants. At the 18-22 s stages, klf8 morphants showed reduced expression of genes encoding Nodal signalling components (spaw, lft1, lft2, and pitx2) in the left LPM, diencephalon, and heart. Co-injection of klf8 mRNA with klf8 morpholino partially rescued spaw expression. Furthermore, klf8 but not klf8△zf overexpressing embryos showed dysregulated bilateral expression of Nodal signalling components at late somite stages. At the 10s stage, klf8 morphants exhibited reductions in length and number of cilia in Kupffer's vesicle, while at 75% epiboly, fewer dorsal forerunner cells were observed

  9. Exploring Kupffer's Vescicle Through Self Propelled Particle Simulations

    Science.gov (United States)

    Lundy, Kassidy; Dasgupta, Agnik; Amack, Jeff; Manning, M. Lisa

    Early development is an important stage in the formation of functional, relatively healthy organisms. In zebrafish embryos, a transient organ in the tailbud called Kupffer's Vescicle (KV) is responsible for the initial left-right (L-R) asymmetry that results in asymmetric organ and tissue placement in the adult zebrafish. Originating as a collection of symmetrically organized monociliated cells, the KV experiences a shift in cell shapes over time that leaves more cells on the anterior or top side of the KV. This arrangement helps to generate a stronger counter-clockwise fluid flow across the anterior side of the organ, which is required for L-R asymmetry. In seeking to understand the source of the shape changes occurring within the KV, we simulate a Self Propelled Particle (SPP) model that includes parameters for cell polarization and speed. We model the KV as a large particle moving in a straight line with constant velocity to mimic the physical forces of the notochord acting on this organ, and we model the surrounding tailbud cells as smaller, slower active particles with an orientation that changes over time due to rotational noise. Our goal is to calculate the forces exerted on the KV by the surrounding tissue, to see if they are sufficient to explain the shape changes we observe in the KV that lead to L-R asymmetry.

  10. Tattoo Pigments Are Observed in the Kupffer Cells of the Liver Indicating Blood-Borne Distribution of Tattoo Ink

    DEFF Research Database (Denmark)

    Sepehri, Mitra; Steen Sejersen, Tobias; Qvortrup, Klaus

    2017-01-01

    AIM: Tattoo pigments are deposited in the skin and known to distribute to regional lymph nodes. Tattoo pigments are small particles and may be hypothesized to reach the blood stream and become distributed to peripheral organs. This has not been studied in the past. The aim of the study was to trace....... Mice were sacrificed after 1 year. Samples were isolated from tattooed skin, lymph nodes, liver, spleen, kidney, and lung. Samples were examined for deposits of tattoo pigments by light microscopy and transmission electron microscopy (TEM). RESULTS: TEM identified intracellular tattoo pigments...... in the skin and in lymph nodes. TEM in both groups of tattooed mice showed tattoo pigment deposits in the Kupffer cells in the liver, which is a new observation. TEM detected no pigment in other internal organs. Light microscopy showed dense pigment in the skin and in lymph nodes but not in internal organs...

  11. Long live the liver: immunohistochemical and stereological study of hepatocytes, liver sinusoidal endothelial cells, Kupffer cells and hepatic stellate cells of male and female rats throughout ageing.

    Science.gov (United States)

    Marcos, Ricardo; Correia-Gomes, Carla

    2016-12-01

    Male/female differences in enzyme activity and gene expression in the liver are known to be attenuated with ageing. Nevertheless, the effect of ageing on liver structure and quantitative cell morphology remains unknown. Male and female Wistar rats aged 2, 6, 12 and 18 months were examined by means of stereological techniques and immunohistochemical tagging of hepatocytes (HEP), liver sinusoidal endothelial cells (LSEC), Kupffer cells (KC) and hepatic stellate cells (HSC) in order to assess the total number and number per gram of these cells throughout life. The mean cell volume of HEP and HSC, the lobular position and the collagen content of the liver were also evaluated with stereological techniques. The number per gram of HSC was similar for both genders and was maintained throughout ageing. The mean volume of HSC was also conserved but differences in the cell body and lobular location were observed. Statistically significant gender differences in HEP were noted in young rats (females had smaller and more binucleated HEP) but were attenuated with ageing. The same occurred for KC and LSEC, since the higher number per gram in young females disappeared in older animals. Liver collagen increased with ageing but only in males. Thus, the numbers of these four cell types are related throughout ageing, with well-defined cell ratios. The shape and lobular position of HSC change with ageing in both males and females. Gender dimorphism in HEP, KC and LSEC of young rat liver disappears with ageing.

  12. Re-evaluation of thin layer chromatography as an alternative method for the quantification of prostaglandins from rat Kupffer cells.

    Science.gov (United States)

    Pestel, Sabine; Jungermann, Kurt; Schieferdecker, Henrike L

    2005-01-01

    In contrast to conventionally used immunoassays, thin layer chromatography (TLC)--by prelabeling of cells with radioactive arachidonic acid (AA)--allows to differentiate between cellularly built and added prostanoids and thus to investigate feedback effects of prostanoids on their own release. PGD2, TXB2 and PGE2 released from zymosan-stimulated Kupffer cells were separated with distinct RF-values, corresponding to those of the pure substances. Quantification of PGD2 and PGE2 gave comparable results with TLC and immunoassays, but measurement in the presence of added prostanoids was only possible with TLC. Moreover TLC was superior to immunoassays in having a longer linear range while being comparably sensitive. Cellularly built TXB2 in its radioactively labeled form was not detectable by TLC. Inhibition of TXB2 release by externally added AA or technical artifacts were excluded, suggesting that the cellular AA-pools used for prostaglandin and thromboxane synthesis differ in their accessibility for added AA. Thus, TLC is a simple, sensitive and precise method for the quantification of cellularly built prostaglandins but not of thromboxane even in the presence of added prostanoids.

  13. beta-oxidation modulates metabolic competition between eicosapentaenoic acid and arachidonic acid regulating prostaglandin E(2) synthesis in rat hepatocytes-Kupffer cells

    DEFF Research Database (Denmark)

    Du, Zhen-Yu; Ma, Tao; Winterthun, Synnøve

    2010-01-01

    and eicosapentaenoic acid (EPA) for PGE(2) synthesis in a rat hepatocyte-Kupffer cell (HPC/KC) co-culture system when the cellular oxidation capacity was enhanced by exogenous l-carnitine. We demonstrate that in the absence of l-carnitine, 1) beta-oxidation rates of EPA and AA were comparable in HPCs and in KCs; 2) AA...... and not EPA was preferentially incorporated into glycerolipids; and 3) addition of EPA significantly decreased AA-dependent PGE(2) synthesis in HPCs and cyclooxygenase-2 (COX-2) expression in co-cultured HPCs/KCs. However, enhancing the cellular oxidation capacity by the addition of l-carnitine 1...... inhibition of AA-dependent PGE(2) synthesis and COX-2 expression by EPA. Taken together, the results strongly suggest that l-carnitine affects competition between AA and EPA in PG synthesis in liver cells by enhancing oxidation of EPA in HPCs. This implies that the beneficial effects of n-3 PUFA, especially...

  14. Transcriptome atlas of eight liver cell types uncovers effects of ...

    Indian Academy of Sciences (India)

    ... types, and bioinformatic and systems biology approaches were employed to analyse the relationship between above genes and rat liver regeneration. The results showed that the urocanic acid (UA) was degraded from histidine in Kupffer cells, acts on Kupffer cells itself and dendritic cells to generate immune suppression ...

  15. Biofilm-Forming Methicillin-Resistant Staphylococcus aureus Survive in Kupffer Cells and Exhibit High Virulence in Mice

    Directory of Open Access Journals (Sweden)

    Takuto Oyama

    2016-06-01

    Full Text Available Although Staphylococcus aureus is part of the normal body flora, heavy usage of antibiotics has resulted in the emergence of methicillin-resistant strains (MRSA. MRSA can form biofilms and cause indwelling foreign body infections, bacteremia, soft tissue infections, endocarditis, and osteomyelitis. Using an in vitro assay, we screened 173 clinical blood isolates of MRSA and selected 20 high-biofilm formers (H-BF and low-biofilm formers (L-BF. These were intravenously administered to mice and the general condition of mice, the distribution of bacteria, and biofilm in the liver, lung, spleen, and kidney were investigated. MRSA count was the highest in the liver, especially within Kupffer cells, which were positive for acid polysaccharides that are associated with intracellular biofilm. After 24 h, the general condition of the mice worsened significantly in the H-BF group. In the liver, bacterial deposition and aggregation and the biofilm-forming spot number were all significantly greater for H-BF group than for L-BF. CFU analysis revealed that bacteria in the H-BF group survived for long periods in the liver. These results indicate that the biofilm-forming ability of MRSA is a crucial factor for intracellular persistence, which could lead to chronic infections.

  16. Curative Effects of Thiacremonone against Acetaminophen-Induced Acute Hepatic Failure via Inhibition of Proinflammatory Cytokines Production and Infiltration of Cytotoxic Immune Cells and Kupffer Cells

    Directory of Open Access Journals (Sweden)

    Yu Ri Kim

    2013-01-01

    Full Text Available High doses of acetaminophen (APAP; N-acetyl-p-aminophenol cause severe hepatotoxicity after metabolic activation by cytochrome P450 2E1. This study was undertaken to examine the preventive effects of thiacremonone, a compound extracted from garlic, on APAP-induced acute hepatic failure in male C57BL/6J. Mice received with 500 mg/kg APAP after a 7-day pretreatment with thiacremonone (10–50 mg/kg. Thiacremonone inhibited the APAP-induced serum ALT and AST levels in a dose-dependent manner, and markedly reduced the restricted area of necrosis and inflammation by administration of APAP. Thiacremonone also inhibited the APAP-induced depletion of intracellular GSH, induction of nitric oxide, and lipid peroxidation as well as expression of P450 2E1. After APAP injection, the numbers of Kupffer cells, natural killer cells, and cytotoxic T cells were elevated, but the elevated cell numbers in the liver were reduced in thiacremonone pretreated mice. The expression levels of I-309, M-CSF, MIG, MIP-1α, MIP-1β, IL-7, and IL-17 were increased by APAP treatment, which were inhibited in thiacremonone pretreated mice. These data indicate that thiacremonone could be a useful agent for the treatment of drug-induced hepatic failure and that the reduction of cytotoxic immune cells as well as proinflammatory cytokine production may be critical for the prevention of APAP-induced acute liver toxicity.

  17. Kupffer cell depletion attenuates leptin-mediated methoxamine-stimulated portal perfusion pressure and thromboxane A2 release in a rodent model of NASH-cirrhosis.

    Science.gov (United States)

    Yang, Ying-Ying; Huang, Yi-Tsau; Tsai, Tung-Hu; Hou, Ming-Chih; Lee, Fa-Yauh; Lee, Shou-Dong; Lin, Han-Chieh

    2012-12-01

    Cirrhotic portal hypertension is characterized by increased hepatic oxidative stress, AA (arachidonic acid)-derived TXA(2) (thromboxane A(2)) release and exaggerated hepatic response to the α-adrenergic agonist MTX (methoxamine). Besides promoting hepatic fibrosis, the role of hyperleptinaemia in the modulation of vascular response in NASH (non-alcoholic steatohepatitis) rat livers remains unknown. The aim of the present study was to explore the possible links between hyperleptinaemia and the disarrangement in the hepatic microcirculation. NASH-cirrhosis with hyperleptinaemia was induced in lean rats by feeding with an HF/MCD (high-fat/methionine-choline-deficient) diet. Portal haemodynamics, various substances, protein and mRNA expression and PUFA (polyunsaturated fatty acid) composition were measured. Finally, the effects of leptin pre-infusion on TXA(2) release and concentration-PPP (portal perfusion pressure) curves in response to MTX were evaluated by simultaneously pre-treatment with the Kupffer cell inactivators GdCl(3) (gadolinium chloride) or EC (encapsulated clodronate), the TXS (TXA(2) synthase) inhibitor furegrelate, the TP receptor (TXA(2) receptor) antagonist SQ29548 and the dual TXS/TP receptor antagonist BM567. In HF/MCD+leptin-lean rats, cirrhosis-induced PPP and MTX hyper-responsiveness were associated with increased hepatic TXA(2) production, TBARS (thiobarbituric acid-reacting substances) levels and the AA (arachidonic acid)/n-3 PUFA ratio, and up-regulation of hepatic leptin, FAS (fatty acid synthase), NADPH oxidase subunits, TXS, TP receptor, TGFβ(1) (transforming growth factor β(1)) proteins and mRNAs. Pre-infusion of leptin significantly enhanced MTX-stimulated PPP elevation and TXA(2) release, which were attenuated by GdCl(3) and EC pre-treatment. Concomitantly pre-incubation with BM567, but not furegrelate or SQ29548, significantly abolished the leptin-enhanced MTX-stimulated increase in PPP in NASH-cirrhotic rats. Hyperleptinaemia

  18. The Future of Animals, Cells, Models, and Systems in Research, Development, Education, and Testing: Proceedings of a Symposium.

    Science.gov (United States)

    National Academy of Sciences - National Research Council, Washington, DC. Inst. of Lab. Animal Resources.

    This volume contains the prepared papers and discussions of a National Academy of Sciences - National Research Council Symposium on the Future of Animals, Cells, Models, and Systems in Research, Development, Education, and Testing. The purpose of the symposium was to examine the past, present, and future contributions of animals to human health…

  19. The 12th International Symposium on Spermatology

    Science.gov (United States)

    Aitken, R John; Cummins, Jim M; Nixon, Brett

    2015-01-01

    The 12th International Symposium of Spermatology continued the excellent tradition of this meeting since its inception in 1969 when the first Symposium was held in Italy under the Chairmanship of Professor Baccio Baccetti. This unique Symposium is held every 4 years and serves as a beacon for sperm cell biologists from all over the world, regardless of which species, animal or plant, they are working on. This willingness to embrace the fundamental biology of this distinctive cell type without species limitations is one of the hallmarks of this Symposium. For sperm biologists – it is our Olympics. The meeting in Newcastle, NSW brought together around 300 biologists from more than 22 different countries covering North and South America, Africa, Europe, Asia and Australia. Given the considerable distances and high cost involved in travelling to the East Coast of NSW, this was an outstanding outcome. The Symposium featured a series of 31 plenary lectures culminating in the prestigious Thaddeus Mann Memorial Lecture, which was delivered with typical grace and brilliance by Professor Masaru Okabe. PMID:25994646

  20. Sixth BHD Symposium and First International Upstate Kidney Cancer Symposium: latest scientific and clinical discoveries

    OpenAIRE

    Bratslavsky, Gennady; Woodford, Mark R.; Daneshvar, Michael; Mollapour, Mehdi

    2016-01-01

    The Sixth BHD Symposium and First International Upstate Kidney Cancer Symposium concluded in September 2015, in Syracuse, NY, USA. The program highlighted recent findings in a variety of areas, including drug development, therapeutics and surgical management of patients with BHD and multi-focal renal tumors, as well as multidisciplinary approaches for patients with localized, locally advanced and metastatic renal cell carcinoma.

  1. Sixth BHD Symposium and First International Upstate Kidney Cancer Symposium: latest scientific and clinical discoveries.

    Science.gov (United States)

    Bratslavsky, Gennady; Woodford, Mark R; Daneshvar, Michael; Mollapour, Mehdi

    2016-03-29

    The Sixth BHD Symposium and First International Upstate Kidney Cancer Symposium concluded in September 2015, in Syracuse, NY, USA. The program highlighted recent findings in a variety of areas, including drug development, therapeutics and surgical management of patients with BHD and multi-focal renal tumors, as well as multidisciplinary approaches for patients with localized, locally advanced and metastatic renal cell carcinoma.

  2. Subtoxic Concentrations of Hepatotoxic Drugs Lead to Kupffer Cell Activation in a Human In Vitro Liver Model: An Approach to Study DILI

    Directory of Open Access Journals (Sweden)

    Victoria Kegel

    2015-01-01

    Full Text Available Drug induced liver injury (DILI is an idiosyncratic adverse drug reaction leading to severe liver damage. Kupffer cells (KC sense hepatic tissue stress/damage and therefore could be a tool for the estimation of consequent effects associated with DILI. Aim of the present study was to establish a human in vitro liver model for the investigation of immune-mediated signaling in the pathogenesis of DILI. Hepatocytes and KC were isolated from human liver specimens. The isolated KC yield was 1.2±0.9×106 cells/g liver tissue with a purity of >80%. KC activation was investigated by the measurement of reactive oxygen intermediates (ROI, DCF assay and cell activity (XTT assay. The initial KC activation levels showed broad donor variability. Additional activation of KC using supernatants of hepatocytes treated with hepatotoxic drugs increased KC activity and led to donor-dependent changes in the formation of ROI compared to KC incubated with supernatants from untreated hepatocytes. Additionally, a compound- and donor-dependent increase in proinflammatory cytokines or in anti-inflammatory cytokines was detected. In conclusion, KC related immune signaling in hepatotoxicity was successfully determined in a newly established in vitro liver model. KC were able to detect hepatocyte stress/damage and to transmit a donor- and compound-dependent immune response via cytokine production.

  3. Subtoxic Concentrations of Hepatotoxic Drugs Lead to Kupffer Cell Activation in a Human In Vitro Liver Model: An Approach to Study DILI

    Science.gov (United States)

    Kegel, Victoria; Pfeiffer, Elisa; Burkhardt, Britta; Liu, Jia L.; Zeilinger, Katrin; Nüssler, Andreas K.; Seehofer, Daniel; Damm, Georg

    2015-01-01

    Drug induced liver injury (DILI) is an idiosyncratic adverse drug reaction leading to severe liver damage. Kupffer cells (KC) sense hepatic tissue stress/damage and therefore could be a tool for the estimation of consequent effects associated with DILI. Aim of the present study was to establish a human in vitro liver model for the investigation of immune-mediated signaling in the pathogenesis of DILI. Hepatocytes and KC were isolated from human liver specimens. The isolated KC yield was 1.2 ± 0.9 × 106 cells/g liver tissue with a purity of >80%. KC activation was investigated by the measurement of reactive oxygen intermediates (ROI, DCF assay) and cell activity (XTT assay). The initial KC activation levels showed broad donor variability. Additional activation of KC using supernatants of hepatocytes treated with hepatotoxic drugs increased KC activity and led to donor-dependent changes in the formation of ROI compared to KC incubated with supernatants from untreated hepatocytes. Additionally, a compound- and donor-dependent increase in proinflammatory cytokines or in anti-inflammatory cytokines was detected. In conclusion, KC related immune signaling in hepatotoxicity was successfully determined in a newly established in vitro liver model. KC were able to detect hepatocyte stress/damage and to transmit a donor- and compound-dependent immune response via cytokine production. PMID:26491234

  4. Trapping of oxidized LDL in lysosomes of Kupffer cells is a trigger for hepatic inflammation.

    Science.gov (United States)

    Bieghs, Veerle; Walenbergh, Sofie M A; Hendrikx, Tim; van Gorp, Patrick J; Verheyen, Fons; Olde Damink, Steven W; Masclee, Ad A; Koek, Ger H; Hofker, Marten H; Binder, Christoph J; Shiri-Sverdlov, Ronit

    2013-08-01

    Non-alcoholic steatohepatitis (NASH) is characterized by steatosis and inflammation. The transition from steatosis towards NASH represents a key step in pathogenesis, as it will set the stage for further severe liver damage. Under normal conditions, lipoproteins that are endocytosed by Kupffer cells (KCs) are easily transferred from the lysosomes into the cytoplasm. Oxidized LDL (oxLDL) that is taken up by the macrophages in vitro is trapped within the lysosomes, while acetylated LDL (acLDL) is leading to normal lysosomal hydrolysis, resulting in cytoplasmic storage. We have recently demonstrated that hepatic inflammation is correlated with lysosomal trapping of lipids. So far, a link between lysosomal trapping of oxLDL and inflammation was not established. We hypothesized that lysosomal trapping of oxLDL in KCs will lead to hepatic inflammation. Ldlr(-/-) mice were injected with LDL, acLDL and oxLDL and sacrificed after 2, 6 and 24 h. Electron microscopy of KCs demonstrated that after oxLDL injection, small lipid inclusions were present inside the lysosomes after all time points and were mostly pronounced after 6 and 24 h. In contrast, no lipid inclusions were present inside KCs after LDL or acLDL injection. Hepatic expression of several inflammatory genes and scavenger receptors was higher after oxLDL injections compared with LDL or acLDL. These data suggest that trapping of oxLDL inside lysosomes of KCs in vivo is causally linked to increased hepatic inflammatory gene expression. Our novel observations provide new bases for prevention and treatment of NASH. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  5. SYMPOSIUM ON PLANT PROTEIN PHOSPHORYLATION

    Energy Technology Data Exchange (ETDEWEB)

    JOHN C WALKER

    2011-11-01

    Protein phosphorylation and dephosphorylation play key roles in many aspects of plant biology, including control of cell division, pathways of carbon and nitrogen metabolism, pattern formation, hormonal responses, and abiotic and biotic responses to environmental signals. A Symposium on Plant Protein Phosphorylation was hosted on the Columbia campus of the University of Missouri from May 26-28, 2010. The symposium provided an interdisciplinary venue at which scholars studying protein modification, as it relates to a broad range of biological questions and using a variety of plant species, presented their research. It also provided a forum where current international challenges in studies related to protein phosphorylation could be examined. The symposium also stimulated research collaborations through interactions and networking among those in the research community and engaged students and early career investigators in studying issues in plant biology from an interdisciplinary perspective. The proposed symposium, which drew 165 researchers from 13 countries and 21 States, facilitated a rapid dissemination of acquired knowledge and technical expertise regarding protein phosphorylation in plants to a broad range of plant biologists worldwide.

  6. Kupffer cells activation promoted binge drinking-induced fatty liver by activating lipolysis in white adipose tissues.

    Science.gov (United States)

    Zhao, Yu-Ying; Yang, Rui; Xiao, Mo; Guan, Min-Jie; Zhao, Ning; Zeng, Tao

    2017-09-01

    Kupffer cells (KCs) have been suggested to play critical roles in chronic ethanol induced early liver injury, but the role of KCs in binge drinking-induced hepatic steatosis remains unclear. This study was designed to investigate the roles of KCs inhibitor (GdCl 3 ) and TNF-α antagonist (etanercept) on binge drinking-induced liver steatosis and to explore the underlying mechanisms. C57BL/6 mice were exposed to three doses of ethanol (6g/kg body weight) to mimic binge drinking-induced fatty liver. The results showed that both GdCl 3 and etanercept partially but significantly alleviated binge drinking-induced increase of hepatic triglyceride (TG) level, and reduced fat droplets accumulation in mice liver. GdCl 3 but not etanercept significantly blocked binge drinking-induced activation of KCs. However, neither GdCl 3 nor etanercept could affect binge drinking-induced decrease of PPAR-α, ACOX, FAS, ACC and SCD protein levels, or increase of the LC3 II/LC3 I ratio and p62 protein level. Interestingly, both GdCl 3 and etanercept significantly suppressed binge drinking-induced phosphorylation of HSL in epididymal adipose tissues. Results of in vitro studies with cultured epididymal adipose tissues showed that TNF-α could increase the phosphorylation of HSL in adipose tissues and upgrade the secretion of free fatty acid (FFA) in the culture medium. Taken together, KCs inhibitor and TNF-α antagonist could partially attenuate binge drinking-induced liver steatosis, which might be attributed to the suppression of mobilization of white adipose tissues. These results suggest that KCs activation may promote binge drinking-induced fatty liver by TNF-α mediated activation of lipolysis in white adipose tissues. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. Symposium on single cell analysis and genomic approaches, Experimental Biology 2017 Chicago, Illinois, April 23, 2017.

    Science.gov (United States)

    Coller, Hilary A

    2017-09-01

    Emerging technologies for the analysis of genome-wide information in single cells have the potential to transform many fields of biology, including our understanding of cell states, the response of cells to external stimuli, mosaicism, and intratumor heterogeneity. At Experimental Biology 2017 in Chicago, Physiological Genomics hosted a symposium in which five leaders in the field of single cell genomics presented their recent research. The speakers discussed emerging methodologies in single cell analysis and critical issues for the analysis of single cell data. Also discussed were applications of single cell genomics to understanding the different types of cells within an organism or tissue and the basis for cell-to-cell variability in response to stimuli. Copyright © 2017 the American Physiological Society.

  8. Claudin5a is required for proper inflation of Kupffer's vesicle lumen and organ laterality.

    Directory of Open Access Journals (Sweden)

    Jeong-Gyun Kim

    Full Text Available Left-right asymmetric organ development is critical to establish a proper body plan of vertebrates. In zebrafish, the Kupffer's vesicle (KV is a fluid-filled sac which controls asymmetric organ development, and a properly inflated KV lumen by means of fluid influx is a prerequisite for the asymmetric signal transmission. However, little is known about the components that support the paracellular tightness between the KV luminal epithelial cells to sustain hydrostatic pressure during KV lumen expansion. Here, we identified that the claudin5a (cldn5a is highly expressed at the apical surface of KV epithelial cells and tightly seals the KV lumen. Downregulation of cldn5a in zebrafish showed a failure in organ laterality that resulted from malformed KV. In addition, accelerated fluid influx into KV by combined treatment of forskolin and 3-isobutyl-1-methylxanthine failed to expand the partially-formed KV lumen in cldn5a morphants. However, malformed KV lumen and defective heart laterality in cldn5a morphants were significantly rescued by exogenous cldn5a mRNA, suggesting that the tightness between the luminal epithelial cells is important for KV lumen formation. Taken together, these findings suggest that cldn5a is required for KV lumen inflation and left-right asymmetric organ development.

  9. Claudin5a is required for proper inflation of Kupffer's vesicle lumen and organ laterality.

    Science.gov (United States)

    Kim, Jeong-Gyun; Bae, Sung-Jin; Lee, Hye Shin; Park, Ji-Hyeon; Kim, Kyu-Won

    2017-01-01

    Left-right asymmetric organ development is critical to establish a proper body plan of vertebrates. In zebrafish, the Kupffer's vesicle (KV) is a fluid-filled sac which controls asymmetric organ development, and a properly inflated KV lumen by means of fluid influx is a prerequisite for the asymmetric signal transmission. However, little is known about the components that support the paracellular tightness between the KV luminal epithelial cells to sustain hydrostatic pressure during KV lumen expansion. Here, we identified that the claudin5a (cldn5a) is highly expressed at the apical surface of KV epithelial cells and tightly seals the KV lumen. Downregulation of cldn5a in zebrafish showed a failure in organ laterality that resulted from malformed KV. In addition, accelerated fluid influx into KV by combined treatment of forskolin and 3-isobutyl-1-methylxanthine failed to expand the partially-formed KV lumen in cldn5a morphants. However, malformed KV lumen and defective heart laterality in cldn5a morphants were significantly rescued by exogenous cldn5a mRNA, suggesting that the tightness between the luminal epithelial cells is important for KV lumen formation. Taken together, these findings suggest that cldn5a is required for KV lumen inflation and left-right asymmetric organ development.

  10. Tattoo Pigments Are Observed in the Kupffer Cells of the Liver Indicating Blood-Borne Distribution of Tattoo Ink.

    Science.gov (United States)

    Sepehri, Mitra; Sejersen, Tobias; Qvortrup, Klaus; Lerche, Catharina M; Serup, Jørgen

    2017-01-01

    Tattoo pigments are deposited in the skin and known to distribute to regional lymph nodes. Tattoo pigments are small particles and may be hypothesized to reach the blood stream and become distributed to peripheral organs. This has not been studied in the past. The aim of the study was to trace tattoo pigments in internal organs in mice extensively tattooed with 2 different tattoo ink products. Three groups of mice were studied, i.e., 10 tattooed black, 10 tattooed red, and 5 untreated controls. They were tattooed on the entire back with commercial tattoo inks, black and red. Mice were sacrificed after 1 year. Samples were isolated from tattooed skin, lymph nodes, liver, spleen, kidney, and lung. Samples were examined for deposits of tattoo pigments by light microscopy and transmission electron microscopy (TEM). TEM identified intracellular tattoo pigments in the skin and in lymph nodes. TEM in both groups of tattooed mice showed tattoo pigment deposits in the Kupffer cells in the liver, which is a new observation. TEM detected no pigment in other internal organs. Light microscopy showed dense pigment in the skin and in lymph nodes but not in internal organs. The study demonstrated black and red tattoo pigment deposits in the liver; thus, tattoo pigment distributed from the tattooed skin via the blood stream to this important organ of detoxification. The finding adds a new dimension to tattoo pigment distribution in the body, i.e., as observed via the blood in addition to the lymphatic pathway. © 2017 S. Karger AG, Basel.

  11. Honoring the work and life of Leroy C. Stevens. A symposium as part of the International Stem Cell Initiative Workshop.

    Science.gov (United States)

    Graham, Christopher F; Solter, Davor; Gearhart, John D; Nadeau, Joseph H; Knowles, Barbara B

    2016-01-01

    In 2016, a symposium was convened in Leroy C. Stevens' honor, in association with a meeting of the International Stem Cell Initiative (ISCI). ISCI, funded internationally, is composed of a group of ~100 scientists from many countries, under the leadership of Peter Andrews, who have worked together to characterize a significant number of human pluripotent stem cell lines, to monitor their genetic stability and their differentiation into mature cell types and tissues in vitro and in vivo. Those at the ISCI meeting puzzled through one of the thorniest problems in the therapeutic use of the differentiated derivatives of pluripotent stem cells for human therapy; namely, pluripotent stem cells can differentiate into any cell type in the adult organism, but they also have the capacity for unlimited self-renewal, hence if mutated they may have tumorigenic potential. The meeting considered how these cells might become genetically or epigenetically abnormal and how the safety of these cells for human therapeutic uses could be assessed and assured. The symposium was an opportunity to pay tribute to Leroy Stevens and to the basic science origins of this newest aspect of regenerative medicine. It was a time to reflect on the past and on how it can influence the future of our field.

  12. Fuel wood symposium; Symposium Energieholz

    Energy Technology Data Exchange (ETDEWEB)

    Wild, C.; Wauer, A. (comps.)

    2001-07-01

    The Bavarian State Institute of Forestry (LWF) organised a 'Fuel Wood Symposium' in Freising-Weihenstephan on 17.11.2000. The purpose of this specialist conference was to give an overview of the use of biomass, especially wood, as an source of energy. (orig.) [German] Die Bayerische Landesanstalt fuer Wald und Forstwirtschaft richtete am 17.11.2000 in Freising-Weihenstephan das 'Symposium Energieholz' aus. Ziel der Fachtagung war es, einen Ueberblick ueber die energetische Nutzung von Biomasse, insbesondere Holz, zu geben. (orig.)

  13. Army symposium: Electrical energy engineering today; Wehrtechnisches Symposium: Moderne elektrische Energietechnik

    Energy Technology Data Exchange (ETDEWEB)

    Busse, H. (ed.) [Bundesakademie fuer Wehrverwaltung und Wehrtechnik, Mannheim (Germany). Fachgebiet Elektrotechnik und Elektroenergiewesen

    2000-05-01

    This symposium was held in Mannheim on May 20/21, 2000. All aspects of energy engineering were discussed, including electrochemical energy sources like accumulator batteries and fuel cells. The proceedings volume contains 26 papers which reflect the state of the art and current trends in electrical energy engineering in the German army. [German] Das Wehrtechnische Symposium 'Moderne elektrische Energietechnik' wurde von der Lehrabteilung Wehrtechnik der Bundesakademie fuer Wehrverwaltung und Wehrtechnik in Mannheim in der Zeit vom 20.05.-21.05.2000 durchgefuehrt. Das Programm enthaelt die aktuellen Themen der elektrischen Energietechnik. Die elektroschemischen Energiequellen (Batterien und Brennstoffzellen) wurden in das Programm integriert. Dadurch konnte das gesamte Spektrum der Energietechnik vielschichtig dargestellt und in der Diskussion unter z.T. sehr verschiedenen Gesichtspunkten beleuchtet werden. Die im vorliegenden Tagungsband abgedruckten 26 Skripte wurden weder gekuerzt noch ergaenzt. Sie zeigen insgesamt den aktuellen Stand und die erfolgversprechenden Entwicklungstendenzen der elektrischen Energietechnik in der Bundeswehr auf. (orig.)

  14. IUTAM Symposium

    CERN Document Server

    1995-01-01

    The International Union of Theoretical and Applied Mechanics (IUTAM) decided in 1992 to sponsor the fourth Symposium on Laminar-Turbulent Transition, Sendai/Japan, 1994. The objectives of the present Symposium were to deepen the fundamental knowledge of stability and laminar­ turbulent transition in three-dimensional and compressible flows and to contribute to recent developing technologies in the field. This Symposium followed the three previous IUTAM-Symposia (Stuttgart 1979, Novosibirsk 1984 and Toulouse 1989). The Scientific Committee selected two keynote lectures and 62 technical papers. The Symposium was held on the 5th to 9th of September, 1994, at the Sendai International Center in Sendai. The participants were 82 scientists from 10 countries. The keynote lectures have critically reviewed recent development of researches concerning the laminar-to-turbulent transition phenomena from the fundamental and the application aspects. Many papers presented were concerned about the detailed mechanism of the bo...

  15. Proceedings of DAE-BRNS third international symposium on materials chemistry

    International Nuclear Information System (INIS)

    Tyagi, Deepak; Banerjee, Atindra Mohan; Nigam, Sandeep; Varma, Salil; Tripathi, Arvind Kumar; Bharadwaj, Shyamala Rajkumar; Das, Dasarathi

    2010-12-01

    The present volume consists of the proceedings of the DAE-BRNS Third International Symposium on Materials Chemistry. In order to keep pace with the advancements made in the area of materials chemistry, new topics like materials for energy conversion, biomaterials, carbon based materials, soft condensed materials, thin films, surface chemistry, polymer based materials, organic and organometallics, magnetic materials and high purity materials have been included in this symposium while topics like nuclear materials, nanomaterials and clusters, catalysis, chemical sensors, fuel cell materials and computational research in materials chemistry have been continued as important features of the symposium. Papers relevant to INIS are indexed separately

  16. Chronic Ethanol Feeding Modulates Inflammatory Mediators, Activation of Nuclear Factor-κB, and Responsiveness to Endotoxin in Murine Kupffer Cells and Circulating Leukocytes

    Directory of Open Access Journals (Sweden)

    Miriam Maraslioglu

    2014-01-01

    Full Text Available Chronic ethanol abuse is known to increase susceptibility to infections after injury, in part, by modification of macrophage function. Several intracellular signalling mechanisms are involved in the initiation of inflammatory responses, including the nuclear factor-κB (NF-κB pathway. In this study, we investigated the systemic and hepatic effect of chronic ethanol feeding on in vivo activation of NF-κB in NF-κBEGFP reporter gene mice. Specifically, the study focused on Kupffer cell proinflammatory cytokines IL-6 and TNF-α and activation of NF-κB after chronic ethanol feeding followed by in vitro stimulation with lipopolysaccharide (LPS. We found that chronic ethanol upregulated NF-κB activation and increased hepatic and systemic proinflammatory cytokine levels. Similarly, LPS-stimulated IL-1β release from whole blood was significantly enhanced in ethanol-fed mice. However, LPS significantly increased IL-6 and TNF-α levels. These results demonstrate that chronic ethanol feeding can improve the responsiveness of macrophage LPS-stimulated IL-6 and TNF-α production and indicate that this effect may result from ethanol-induced alterations in intracellular signalling through NF-κB. Furthermore, LPS and TNF-α stimulated the gene expression of different inflammatory mediators, in part, in a NF-κB-dependent manner.

  17. The Fourth Nagoya International Blood and Marrow Transplantation Symposium: new horizons in allogeneic hematopoietic cell transplantation--2001 revolution.

    Science.gov (United States)

    Sao, Hiroshi; Morishita, Yoshihisa

    2002-02-01

    In this symposium, we saw new horizons in allogeneic transplantation. Are these truly revolutionary? We do not yet know the answer. However, there is no question about the importance of allogeneic T cells. T cells are much more powerful than any pharmacological drug man has ever generated. The question is, how do we take the most advantage of their potential. Every participant was encouraged to search for good answers to this question until the next meeting.

  18. Loss of lysosomal membrane protein NCU-G1 in mice results in spontaneous liver fibrosis with accumulation of lipofuscin and iron in Kupffer cells

    Directory of Open Access Journals (Sweden)

    Xiang Y. Kong

    2014-03-01

    Full Text Available Human kidney predominant protein, NCU-G1, is a highly conserved protein with an unknown biological function. Initially described as a nuclear protein, it was later shown to be a bona fide lysosomal integral membrane protein. To gain insight into the physiological function of NCU-G1, mice with no detectable expression of this gene were created using a gene-trap strategy, and Ncu-g1gt/gt mice were successfully characterized. Lysosomal disorders are mainly caused by lack of or malfunctioning of proteins in the endosomal-lysosomal pathway. The clinical symptoms vary, but often include liver dysfunction. Persistent liver damage activates fibrogenesis and, if unremedied, eventually leads to liver fibrosis/cirrhosis and death. We demonstrate that the disruption of Ncu-g1 results in spontaneous liver fibrosis in mice as the predominant phenotype. Evidence for an increased rate of hepatic cell death, oxidative stress and active fibrogenesis were detected in Ncu-g1gt/gt liver. In addition to collagen deposition, microscopic examination of liver sections revealed accumulation of autofluorescent lipofuscin and iron in Ncu-g1gt/gt Kupffer cells. Because only a few transgenic mouse models have been identified with chronic liver injury and spontaneous liver fibrosis development, we propose that the Ncu-g1gt/gt mouse could be a valuable new tool in the development of novel treatments for the attenuation of fibrosis due to chronic liver damage.

  19. Proceedings of the 2016 National Toxicology Program Satellite Symposium.

    Science.gov (United States)

    Elmore, Susan A; Chen, Vivian S; Hayes-Bouknight, Schantel; Hoane, Jessica S; Janardhan, Kyathanahalli; Kooistra, Linda H; Nolte, Thomas; Szabo, Kathleen A; Willson, Gabrielle A; Wolf, Jeffrey C; Malarkey, David E

    2017-01-01

    The 2016 annual National Toxicology Program Satellite Symposium, entitled "Pathology Potpourri" was held in San Diego, CA, at the Society of Toxicologic Pathology's (STP) 35th annual meeting. The goal of this symposium was to present and discuss challenging diagnostic pathology and/or nomenclature issues. This article presents summaries of the speakers' talks, along with select images that were used by the audience for voting and discussion. Some lesions and topics covered during the symposium included malignant glioma and histiocytic sarcoma in the rodent brain; a new statistical method designed for histopathology data evaluation; uterine stromal/glandular polyp in a rat; malignant plasma cell tumor in a mouse brain; Schwann cell proliferative lesions in rat hearts; axillary schwannoma in a cat; necrosis and granulomatous inflammation in a rat brain; adenoma/carcinoma in a rat adrenal gland; hepatocyte maturation defect and liver/spleen hematopoietic defects in an embryonic mouse; distinguishing malignant glioma, malignant mixed glioma, and malignant oligodendroglioma in the rat; comparison of mammary gland whole mounts and histopathology from mice; and discussion of the International Harmonization of Nomenclature and Diagnostic Criteria collaborations.

  20. Ocular Stem Cell Research from Basic Science to Clinical Application: A Report from Zhongshan Ophthalmic Center Ocular Stem Cell Symposium

    Directory of Open Access Journals (Sweden)

    Hong Ouyang

    2016-03-01

    Full Text Available Stem cells hold promise for treating a wide variety of diseases, including degenerative disorders of the eye. The eye is an ideal organ for stem cell therapy because of its relative immunological privilege, surgical accessibility, and its being a self-contained system. The eye also has many potential target diseases amenable to stem cell-based treatment, such as corneal limbal stem cell deficiency, glaucoma, age-related macular degeneration (AMD, and retinitis pigmentosa (RP. Among them, AMD and glaucoma are the two most common diseases, affecting over 200 million people worldwide. Recent results on the clinical trial of retinal pigment epithelial (RPE cells from human embryonic stem cells (hESCs and induced pluripotent stem cells (iPSCs in treating dry AMD and Stargardt’s disease in the US, Japan, England, and China have generated great excitement and hope. This marks the beginning of the ocular stem cell therapy era. The recent Zhongshan Ophthalmic Center Ocular Stem Cell Symposium discussed the potential applications of various stem cell types in stem cell-based therapies, drug discoveries and tissue engineering for treating ocular diseases.

  1. 4th Abel Symposium

    CERN Document Server

    Friedlander, Eric; Jahren, Björn; Østvær, Paul

    2009-01-01

    The 2007 Abel Symposium took place at the University of Oslo in August 2007. The goal of the symposium was to bring together mathematicians whose research efforts have led to recent advances in algebraic geometry, algebraic K-theory, algebraic topology, and mathematical physics. A common theme of this symposium was the development of new perspectives and new constructions with a categorical flavor. As the lectures at the symposium and the papers of this volume demonstrate, these perspectives and constructions have enabled a broadening of vistas, a synergy between once-differentiated subjects, and solutions to mathematical problems both old and new.

  2. Cell phone data and travel behavior research: symposium summary report

    Science.gov (United States)

    2014-07-01

    This report summarizes the key themes from a symposium held on February 12, 2014, to discuss opportunities and challenges using cellular location data for national travel behavior analysis. Participants discussed the availability of cellular data and...

  3. Risk of Low Dose/Low Dose Rate Ionizing Radiation to Humans Symposium Annual Meeting of the Environmental Mutagen Society: Agenda and Abstracts

    Energy Technology Data Exchange (ETDEWEB)

    Veigl, Martina L. [Environmental Mutagen Society (EMS), Reston, VA (United States); Case Western Reserve Univ., Cleveland, OH (United States). Case Comprehensive Cancer Center; Morgan, William F. [Univ. of Maryland, College Park, MD (United States); Schwartz, Jeffrey L. [Univ. of Washington, Seattle, WA (United States)

    2009-11-11

    The low dose symposium thoughtfully addressed controversy of risk from low dose radiation exposure, hormesis and radon therapy. The stem cell symposium cogently considered the role of DNA damage and repair in hematopoietic stem cells underlying aging and malignancy and provocatively presented evidence that stem cells may have distinct morphologies and replicative properties, as well as special roles in cancer initiation. In the epigenetics symposium, studies illustrated the long range interaction of epigenetic mechanisms, the roles of CTCF and BORIS in region/specific regulation of epigenetic processes, the impact of DNA damage on epigenetic processes as well as links between epigenetic mechanisms and early nutrition and bystander effects. This report shows the agenda and abstracts for this symposium.

  4. Fourth Tennessee water resources symposium

    International Nuclear Information System (INIS)

    Sale, M.J.; Presley, P.M.

    1991-01-01

    The annual Tennessee Water Resources Symposium was initiated in 1988 as a means to bring together people with common interests in the state's important water-related resources at a technical, professional level. Initially the symposium was sponsored by the American Institute of Hydrology and called the Hydrology Symposium, but the Tennessee Section of the American Water Resources Association (AWRA) has taken on the primary coordination role for the symposium over the last two years and the symposium name was changed in 1990 to water resources to emphasize a more inter-disciplinary theme. This year's symposium carries on the successful tradition of the last three years. Our goal is to promote communication and cooperation among Tennessee's water resources professionals: scientists, engineers, and researchers from federal, state, academic, and private institutions and organizations who have interests and responsibilities for the state's water resources. For these conference proceedings, individual papers are processed separately for the Energy Data Base

  5. Verslag 20th Symposium on Housing and Fiseases of Rabbits, Furprovinding animals and Pet animals

    NARCIS (Netherlands)

    Rommers, J.M.

    2017-01-01

    Op 17 en 18 mei jl. werd in Celle (Duitsland) het Symposium on Housing
    and Diseases of Rabbits, Furproviding animals and Pet animals
    gehouden. Dit symposium wordt eenmaal per twee jaar georganiseerd
    door Duitsland. Er waren circa 60 deelnemers uit 12 verschillende
    landen, waaronder

  6. COST 516 Tribology Symposium

    Energy Technology Data Exchange (ETDEWEB)

    Ronkainen, H.; Holmberg, K. [eds.

    1998-11-01

    Cost 516 Tribology action is the first joint European research action focusing on tribology, which originates in the approval of its Memorandum of understanding in February 1994. The COST 516 Tribology Symposium took place in Espoo, Finland from 14th to 15th May 1998. This was the first Symposium of the COST 516 Tribology action. The large number of research contributions at the Symposium, altogether almost SO, and their scientific and technical level, is an indication of the importance and significance of tribology research. The symposium proceedings contain papers in a wide variety of subjects, covering the three categories of the COST 516 Tribology action, namely Grease lubrication (GRIT), Tribology of renewable environmentally adapted lubricants (REAL) and Coatings and surface treatments (CAST). (orig.)

  7. Seventh International Beaver Symposium

    OpenAIRE

    Yuri A. Gorshkov

    2016-01-01

    The paper presents data on the seventh international Beaver Symposium. Brief historical background about previous Beaver Symposia beaver is shown. Data on the sections of symposium, number of participants and reports are presented.

  8. Symposium Highlights

    International Nuclear Information System (INIS)

    Owen-Whitred, K.

    2015-01-01

    Overview/Highlights: To begin, I'd like to take a moment to highlight some of the novel elements of this Symposium as compared to those that have been held in the past. For the first time ever, this Symposium was organized around five concurrent sessions, covering over 300 papers and presentations. These sessions were complemented by an active series of exhibits put on by vendors, universities, ESARDA, INMM, and Member State Support Programmes. We also had live demonstrations throughout the week on everything from software to destructive analysis to instrumentation, which provided the participants the opportunity to see recent developments that are ready for implementation. I'm sure you all had a chance to observe - and, more importantly, interact with - the electronic Poster, or ePoster format used this past week. This technology was used here for the first time ever by the IAEA, and I'm sure was a first for many of us as well. The ePoster format allowed participants to interact with the subject matter, and the subject matter experts, in a dynamic, engaging way. In addition to the novel technology used here, I have to say that having the posters strategically embedded in the sessions on the same topic, by having each poster author introduce his or her topic to the assembled group in order to lure us to the poster area during the breaks, was also a novel and highly effective technique. A final highlight I'd like to touch on in terms of the Symposium organization is the diversity of participation. This chart shows the breakdown by geographical distribution for the Symposium, in terms of participants. There are no labels, so don't try to read any, I simply wanted to demonstrate that we had great representation in terms of both the Symposium participants in general and the session chairs more specifically-and on that note, I would just mention here that 59 Member States participated in the Symposium. But what I find especially interesting and

  9. Seventh International Beaver Symposium

    Directory of Open Access Journals (Sweden)

    Yuri A. Gorshkov

    2016-05-01

    Full Text Available The paper presents data on the seventh international Beaver Symposium. Brief historical background about previous Beaver Symposia beaver is shown. Data on the sections of symposium, number of participants and reports are presented.

  10. All-In-One: Advanced preparation of Human Parenchymal and Non-Parenchymal Liver Cells.

    Directory of Open Access Journals (Sweden)

    Melanie Werner

    Full Text Available Liver cells are key players in innate immunity. Thus, studying primary isolated liver cells is necessary for determining their role in liver physiology and pathophysiology. In particular, the quantity and quality of isolated cells are crucial to their function. Our aim was to isolate a large quantity of high-quality human parenchymal and non-parenchymal cells from a single liver specimen.Hepatocytes, Kupffer cells, liver sinusoidal endothelial cells, and stellate cells were isolated from liver tissues by collagenase perfusion in combination with low-speed centrifugation, density gradient centrifugation, and magnetic-activated cell sorting. The purity and functionality of cultured cell populations were controlled by determining their morphology, discriminative cell marker expression, and functional activity.Cell preparation yielded the following cell counts per gram of liver tissue: 2.0 ± 0.4 × 10(7 hepatocytes, 1.8 ± 0.5 × 10(6 Kupffer cells, 4.3 ± 1.9 × 10(5 liver sinusoidal endothelial cells, and 3.2 ± 0.5 × 10(5 stellate cells. Hepatocytes were identified by albumin (95.5 ± 1.7% and exhibited time-dependent activity of cytochrome P450 enzymes. Kupffer cells expressed CD68 (94.5 ± 1.2% and exhibited phagocytic activity, as determined with 1 μm latex beads. Endothelial cells were CD146(+ (97.8 ± 1.1% and exhibited efficient uptake of acetylated low-density lipoprotein. Hepatic stellate cells were identified by the expression of α-smooth muscle actin (97.1 ± 1.5%. These cells further exhibited retinol (vitamin A-mediated autofluorescence.Our isolation procedure for primary parenchymal and non-parenchymal liver cells resulted in cell populations of high purity and quality, with retained physiological functionality in vitro. Thus, this system may provide a valuable tool for determining liver function and disease.

  11. IUTAM Symposium

    CERN Document Server

    Whitelaw, James; Wung, T

    1992-01-01

    A Symposium on Aerothermodynamics of Combustors was held at the Institute of Applied Mechanics of the National Taiwan University from 3 to 5 June 1991 and was attended by 130 delegates from eight countries. The topics of the forty formal presentations included measurements and calculations of isothermal simulations and of combusting flows with one and two phases, and with consideration of configurations ranging from simple diffusion to gas-turbine flows. The discussions inside and outside of the Symposium Hall were lively and an open forum session demonstrated the range of opinions currently and strongly held. The International Union of Theoretical and Applied Mechanics initiated the Symposium under the chairmanship of Professor R S L Lee and with the Scientific Committee listed below. It benefited from sponsorship, again as listed below, and from contributors who presented interesting and up-to-date descriptions of their research. Invited lectures were delivered by Professors R Bilger and F Weinberg and set ...

  12. IUTAM Symposium

    CERN Document Server

    Shioiri, Jumpei

    1996-01-01

    The IUTAM Symposium on Constitutive Relation in High/Very High Strain Rates (CRHVHSR) was held October 16 - 19, 1995, at Seminar House, Science University of Tokyo, under the sponsorship of IUTAM, Japan Society for the Promotion of Science, The Commemorative Association for the Japan World Exposition (1970), Inoue Foundation for Science, The Japan Society for Aeronautical and Space Sciences, and Science University of Tokyo. The proposal to hold the symposium was accepted by the General Assembly of IUT AM held in Haifa, Israel, in August 1992, and the scientists mentioned below were appointed by the Bureau of IUTAM to serve as members of the Scientific Committee. The main object of the symposium was to make a general survey of recent developments in the research of constitutive relations in high and very high strain rates and related problems in high velocity solid mechanics, and to explore further new ideas for dealing with unresolved problems of a fundamental nature as well as of practical importance. The su...

  13. Proceedings of the TOUGH Symposium 2009

    Energy Technology Data Exchange (ETDEWEB)

    Moridis, George J.; Doughty, Christine; Finsterle, Stefan; Sonnenthal, Eric

    2009-10-01

    Welcome to the TOUGH Symposium 2009. Within this volume are the Symposium Program for eighty-nine papers to be presented in both oral and poster formats. The full papers are available as pdfs linked from the Symposium Program posted on the TOUGH Symposium 2009 website http://esd.lbl.gov/newsandevents/events/toughsymposium09/program.html Additional updated information including any changes to the Program will also be available at the website. The papers cover a wide range of application areas and reflect the continuing trend toward increased sophistication of the TOUGH codes. A CD containing the proceedings papers will be published immediately following the Symposium and sent to all participants. As in the prior Symposium, selected papers will be invited for submission to a number of journals for inclusion in Special Issues focused on applications and developments of the TOUGH codes. These journals include, Transport in Porous Media, Geothermics, Energy Conversion and Management, Journal of Nuclear Science and Technology, and the Vadose Zone Journal.

  14. Symposium Promotes Technological Literacy through STEM

    Science.gov (United States)

    Havice, Bill; Marshall, Jerry

    2009-01-01

    This article describes a symposium which promotes technological literacy through science, technology, engineering, and mathematics (STEM). The three-day symposium titled, "The Anderson, Oconee, Pickens Symposium on Teaching and Learning STEM Standards for the 21st Century," was held August 4-6, 2008 at the Tri-County Technical College…

  15. Symposium report of Inter-COE international symposium on energy systems

    International Nuclear Information System (INIS)

    2006-10-01

    The symposium of the title aims to discuss a comprehensive possibility of energy system technologies for future society utilizing both specialties of five COEs in energy technology field. The symposium topics include, 'Primary energy production', 'Energy conversion, storage and transportation', 'Energy materials', 'Energy system' by specialists from the COEs. Posters were presented by doctoral course students and others in the COEs, in addition special session 'Energy Research and Human Resources Development'. (J.P.N.)

  16. CLEC4F is an inducible C-type lectin in F4/80-positive cells and is involved in alpha-galactosylceramide presentation in liver.

    Directory of Open Access Journals (Sweden)

    Chih-Ya Yang

    Full Text Available CLEC4F, a member of C-type lectin, was first purified from rat liver extract with high binding affinity to fucose, galactose (Gal, N-acetylgalactosamine (GalNAc, and un-sialylated glucosphingolipids with GalNAc or Gal terminus. However, the biological functions of CLEC4F have not been elucidated. To address this question, we examined the expression and distribution of murine CLEC4F, determined its binding specificity by glycan array, and investigated its function using CLEC4F knockout (Clec4f-/- mice. We found that CLEC4F is a heavily glycosylated membrane protein co-expressed with F4/80 on Kupffer cells. In contrast to F4/80, CLEC4F is detectable in fetal livers at embryonic day 11.5 (E11.5 but not in yolk sac, suggesting the expression of CLEC4F is induced as cells migrate from yolk cells to the liver. Even though CLEC4F is not detectable in tissues outside liver, both residential Kupffer cells and infiltrating mononuclear cells surrounding liver abscesses are CLEC4F-positive upon Listeria monocytogenes (L. monocytogenes infection. While CLEC4F has strong binding to Gal and GalNAc, terminal fucosylation inhibits CLEC4F recognition to several glycans such as Fucosyl GM1, Globo H, Bb3∼4 and other fucosyl-glycans. Moreover, CLEC4F interacts with alpha-galactosylceramide (α-GalCer in a calcium-dependent manner and participates in the presentation of α-GalCer to natural killer T (NKT cells. This suggests that CLEC4F is a C-type lectin with diverse binding specificity expressed on residential Kupffer cells and infiltrating monocytes in the liver, and may play an important role to modulate glycolipids presentation on Kupffer cells.

  17. Crispy Cracks Symposium Explores Crispness and Water Management

    NARCIS (Netherlands)

    Hamer, R.J.; Vliet, van T.

    2008-01-01

    This article provides an overview of the first international symposium on crispness creation and retention. The symposium, entitled, ¿Crispy Cracks Symposium,¿ was organized by Cereals & Europe and TI Food and Nutrition. The symposium contained three sessions: 1) Crispiness¿The Fundamentals; 2)

  18. CONTEXT 2015 Doctorial Symposium

    DEFF Research Database (Denmark)

    Eklund, Peter; wegener, rebekah

    2015-01-01

    What is the CONTEXT 2015 Doctoral Symposium? The CONTEXT 2015 Doctoral Symposium is an opportunity for doctoral researchers to showcase their work and discuss problems, challenges, and ideas in an open and collegial environment with expert feedback. The Doctoral Symposium is a workshop for doctoral...... feedback and general advice in a constructive atmosphere. Doctoral researchers will present and discuss their research in a supportive atmosphere with other doctoral researchers and an international panel of established researchers that provide expert feedback. The workshop will take place on a single full...... day, Monday November 2, 2015, the day prior to the start of the main CONTEXT 2015 conference....

  19. PREFACE: 9th International Fröhlich's Symposium: Electrodynamic Activity of Living Cells (Including Microtubule Coherent Modes and Cancer Cell Physics)

    Science.gov (United States)

    Cifra, Michal; Pokorný, Jirí; Kucera, Ondrej

    2011-12-01

    This volume contains papers presented at the International Fröhlich's Symposium entitled 'Electrodynamic Activity of Living Cells' (1-3 July 2011, Prague, Czech Republic). The Symposium was the 9th meeting devoted to physical processes in living matter organized in Prague since 1987. The hypothesis of oscillation systems in living cells featured by non-linear interaction between elastic and electrical polarization fields, non-linear interactions between the system and the heat bath leading to energy downconversion along the frequency scale, energy condensation in the lowest frequency mode and creation of a coherent state was formulated by H Fröhlich, founder of the theory of dielectric materials. He assumed that biological activity is based not only on biochemical but also on biophysical mechanisms and that their disturbances form basic links along the cancer transformation pathway. Fröhlich outlined general ideas of non-linear physical processes in biological systems. The downconversion and the elastic-polarization interactions should be connected in a unified theory and the solution based on comprehensive non-linear characteristics. Biochemical and genetic research of biological systems are highly developed and have disclosed a variety of cellular and subcellular structures, chemical reactions, molecular information transfer, and genetic code sequences - including their pathological development. Nevertheless, the cancer problem is still a big challenge. Warburg's discovery of suppressed oxidative metabolism in mitochondria in cancer cells suggested the essential role of physical mechanisms (but his discovery has remained without impact on cancer research and on the study of physical properties of biological systems for a long time). Mitochondria, the power plants of the cell, have several areas of activity-oxidative energy production is connected with the formation of a strong static electric field around them, water ordering, and liberation of non

  20. A transgenic rat hepatocyte - Kupffer cell co-culture model for evaluation of direct and macrophage-related effect of poly(amidoamine) dendrimers.

    Science.gov (United States)

    Jemnitz, Katalin; Bátai-Konczos, Attila; Szabó, Mónika; Ioja, Enikő; Kolacsek, Orsolya; Orbán, Tamás I; Török, György; Homolya, László; Kovács, Eszter; Jablonkai, István; Veres, Zsuzsa

    2017-02-01

    Increasing number of papers demonstrate that Kupffer cells (KCs) play a role in the development of drug induced liver injury (DILI). Furthermore, elevated intracellular Ca 2+ level of hepatocytes is considered as a common marker of DILI. Here we applied an in vitro model based on hepatocyte mono- and hepatocyte/KC co-cultures (H/KC) isolated from transgenic rats stably expressing the GCaMP2 fluorescent Ca 2+ sensor protein to investigate the effects of polycationic (G5), polyanionic (G4.5) and polyethylene-glycol coated neutral (G5 Peg) dendrimers known to accumulate in the liver, primarily in KCs. Following dendrimer exposure, hepatocyte homeostasis was measured by MTT cytotoxicity assay and by Ca 2+ imaging, while hepatocyte functions were studied by CYP2B1/2 inducibility, and bilirubin and taurocholate transport. G5 was significantly more cytotoxic than G4.5 for hepatocytes and induced Ca 2+ oscillation and sustained Ca 2+ signals at 1μM and10 μM, respectively both in hepatocytes and KCs. Dendrimer-induced Ca 2+ signals in hepatocytes were attenuated by macrophages. Activation of KCs by lipopolysaccharide and G5 decreased the inducibility of CYP2B1/2, which was restored by depleting the KCs with gadolinium-chloride and pentoxyphylline, suggesting a role of macrophages in the hindrance of CYP2B1/2 induction by G5 and lipopolysaccharide. In the H/KC, but not in the hepatocyte mono-culture, G5 reduced the canalicular efflux of bilirubin and stimulated the uptake and canalicular efflux of taurocholate. In conclusion, H/KC provides a good model for the prediction of hepatotoxic potential of drugs, especially of nanomaterials known to be trapped by macrophages, activation of which presumably contributes to DILI. Copyright © 2016 Elsevier B.V. All rights reserved.

  1. A Real-Time Systems Symposium Preprint.

    Science.gov (United States)

    1983-09-01

    Real - Time Systems Symposium Preprint Interim Tech...estimate of the occurence of the error. Unclassii ledSECUqITY CLASSIF’ICA T" NO MI*IA If’ inDI /’rrd erter for~~ble. ’Corrputnqg A REAL - TIME SYSTEMS SYMPOSIUM...ABSTRACT This technical report contains a preprint of a paper accepted for presentation at the REAL - TIME SYSTEMS SYMPOSIUM, Arlington,

  2. International Symposium on Nuclear Safety

    International Nuclear Information System (INIS)

    2013-03-01

    Nuclear Regulatory Authority of the Slovak Republic and the Embassy of Japan in the Slovak Republic, under the auspices of the Deputy Prime Minister and Minister of Foreign and European Affairs Mr Lajcak organized International Symposium on Nuclear Safety on 14 and 15 March 2013. The symposium took place almost exactly two years after the occurrence of accidents at the Japanese nuclear power plant Fukushima Daichi. The main mission of the symposium was an attempt to contribute to the improvement of nuclear safety by sharing information and lessons presented by Japanese experts with experts from the region, the International Atomic Energy Agency (IAEA) and the European Commission. The aim of the symposium, unlike many other events organized in connection with the events in Fukushima Daichi NPP, was a summary of the results of stress tests and measures update adopted by the international community, especially within Europe. Panel discussion was included to the program of the symposium for this aim was, mainly focused on the current state of implementation of the National Action Plan of the Slovak Republic, the Czech Republic, Poland, Ukraine and Switzerland and the IAEA Action Plan.

  3. XX international {mu}-symposium - Brake conference. Papers; XX Internationales {mu}-Symposium - Bremsen-Fachtagung. Betraege

    Energy Technology Data Exchange (ETDEWEB)

    Breuer, B. [ed.] [Verein Deutscher Ingenieure (VDI), Darmstadt (Germany); Bauer, E. (comp.) [TMD Friction GmbH, Leverkusen (Germany)

    2000-07-01

    This year, more brake experts from the international automotive community than ever will take part in the XXth {mu}-Symposium upon the invitation of TMD Friction and learn about the latest developments in their professional fields, discuss with each other, and listen in the opening speech to the viewpoints of a behavioural scientist on braking as the main focus of {mu}-Symposium and {mu}-Club. The contents of this {mu}-Symposium will be the following: Braking from the behavioural scientist's viewpoint/research on tribological characteristics between Al-MMC brake disc and friction material/SBC - the electro-hydraulic brake system from Mercedes-Benz/total chassis management - heading for the intelligent chassis/TMD Friction - a company profile. (orig./AKF) [German] Bremsenexperten der internationalen Automobilwelt trafen sich im Herbst 2000 zum zwanzigsten Mal auf Einladung von TMD Friction in Bad Neuenahr. Dieser Bericht fasst - jeweils in deutsch und englisch - die Vortraege ueber neueste Entwicklungen aus Industrie und Hochschule zusammen. Im Einfuehrungsvortrag berichtet ein Verhaltenswissenschaftler ueber seine Gedanken zum Bremsen als dem Hauptgegenstand von {mu}-Symposium und {mu}-Club. Ferner gehoeren die Praesentation des elektrohydraulischen Bremssystems ebenso zum Programm des Symposiums wie die Vorstellung von Forschungsergebnissen neuer Reibpaarungen und der Blick auf die Zukunft des Fahrwerks im Verbund mit Fahrzeugregelsystemen. (orig./AKF)

  4. Symposium on neutron scattering

    International Nuclear Information System (INIS)

    Lehmann, M.S.; Saenger, W.; Hildebrandt, G.; Dachs, H.

    1984-01-01

    Extended abstracts of the named symposium are presented. The first part of this report contains the abstracts of the lectures, the second those of the posters. Topics discussed on the symposium include neutron diffraction and neutron scattering studies in magnetism, solid state chemistry and physics, materials research. Some papers discussing instruments and methods are included too. (GSCH)

  5. Proceedings of the second US Department of Energy environmental control symposium. Volume 1. Fossil energy

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-06-01

    These proceedings document the presentations given at the Second Environmental Control Symposium. Symposium presentations highlighted environmental control activities which span the entire DOE. Volume I contains papers relating to coal preparation, oil shales, coal combustion, advanced coal utilization (fluidized bed combustion, MHD generators, OCGT, fuel cells), coal gasification, coal liquefaction, and fossil resource extraction (enhanced recovery). Separate abstracts for individual papers are prepared for inclusion in the Energy Data Base. (DMC)

  6. Lysosomal and endosomal heterogeneity in the liver: A comparison of the intracellular pathways of endocytosis in rat liver cells

    International Nuclear Information System (INIS)

    Kindberg, G.M.; Tolleshaug, H.; Gjoen, T.; Berg, T.

    1991-01-01

    Air-filled albumin microspheres, asialoorosomucoid and formaldehyde-treated serum albumin are selectively taken up by endocytosis in rat liver Kupffer cells, parenchymal cells and endothelial cells, respectively. Intracellular transport and degradation of endocytosed material were studied by subcellular fractionation in sucrose and Nycodenz gradients after intravenous injection of the ligand. By using ligands labeled with 125I-tyramine-cellobiose, the subcellular distribution of labeled degradation products can be studied because they are trapped at the site of formation. The results show that the kinetics of intracellular transport are different in hepatic parenchymal, endothelial and Kupffer cells. In endothelial cells, the ligand is associated with two types of endosomes during the first minutes after internalization and then is transferred rapidly to the lysosomes. In parenchymal cells, 125I-tyramine-cellobiose-asialoorosomucoid was located in a relatively slowly sedimenting vesicle during the first minute after internalization and subsequently in denser endosomes. Degradation of 125I-tyramine-cellobiose-asialoorosomucoid in parenchymal cells started later than that of 125I-tyramine-cellobiose-formaldehyde-treated serum albumin in endothelial cells. Furthermore, the ligand seemed to be transferred relatively slowly from endosomes to lysosomes, and most of the undegraded ligand was in the endosomes. The rate-limiting step of proteolysis in parenchymal cells is probably the transport from endosomes to lysosomes. In Kupffer cells, most 125I-tyramine-cellobiose-microspheres are found as undegraded material in very dense endosomes up to 3 hr after injection. After 20 hr, most of the ligand is degraded in lysosomes distributed at a lower density than the endosomes in Nycodenz and sucrose gradients

  7. Abel Symposium 2015

    CERN Document Server

    Larsen, Nadia; Neshveyev, Sergey; Skau, Christian

    2016-01-01

    Like the first Abel Symposium, held in 2004, the Abel Symposium 2015 focused on operator algebras. It is interesting to see the remarkable advances that have been made in operator algebras over these years, which strikingly illustrate the vitality of the field. A total of 26 talks were given at the symposium on a variety of themes, all highlighting the richness of the subject. The field of operator algebras was created in the 1930s and was motivated by problems of quantum mechanics. It has subsequently developed well beyond its initial intended realm of applications and expanded into such diverse areas of mathematics as representation theory, dynamical systems, differential geometry, number theory and quantum algebra. One branch, known as “noncommutative geometry”, has become a powerful tool for studying phenomena that are beyond the reach of classical analysis. This volume includes research papers that present new results, surveys that discuss the development of a specific line of research, and articles ...

  8. Oslo Epigenetics Symposium 2012. Oslo, Norway, 8-9 November 2012.

    Science.gov (United States)

    Collas, Philippe; Eskeland, Ragnhild

    2013-02-01

    The Oslo Epigenetics Symposium 2012 held in Oslo, Norway, brought together ten speakers from several European countries and the USA for an evening public lecture and a full day of presentations on emerging topics in the field of epigenetics, gene regulation and organization of the cell nucleus.

  9. Radiation-induced DNA damage and repair: Argonne National Laboratory symposium, Argonne, Illinois 60439, 15 April, 1988. Symposium report

    Energy Technology Data Exchange (ETDEWEB)

    Peak, M J; Peak, J G; Blazek, E R

    1988-10-01

    The Argonne National Laboratory Symposium brought together 109 scientists from five countries to discuss the molecular effects of radiation on DNA and the responses of cells to radiation exposure. Six speakers covered three general areas: (1) DNA damages caused by radiations; (2) repair of these damages in prokaryotes and eukaryotes; and (3) aminothiols as radioprotectors. In addition, a round table discussion chaired by J. Ward dealt with alkaline and neutral elution methodology.

  10. Assessment of hepatocyte and kupffer cell function using Tc-99m DISIDA/Tc-99m tin colloid in thioacetamide-induced liver injury

    International Nuclear Information System (INIS)

    Ahn, B. C.; Chun, K. A.; Lee, J.; Lee, K. B.

    1997-01-01

    Toxic liver injury is not unusual in clinical field and liver biopsy is one of the most accurate method to define the severity of liver injury. But occasionally, it is impossible to obtain liver tissue in patients with acute toxic liver injury. The aim of this study is to evaluate the possibility of liver scintigraphy with Tc-99m DISIDA or Tc-99m tin colloid as a non-invasive tool in predicting functional status of hepatocyte and Kupffer cell and severity of liver injury. Intraperitoneal injection of thioacetamide was performed to make acute liver injury in mice and rats, and liver status was assessed by pathologic specimen and scintigraphic methods. Scintigraphic evaluation were performed by biodistribution of Tc-99m DISIDA or Tc-99m tin colloid in thioacetamide-treated mice. Liver time-activity curves were generated. Comparison between histologic data and scintigraphic data was done with SAS program. Thioacetamide-treated mice demonstrated hepatocyte necrosis in histologic examination and low liver/blood uptake ratios in biodistribution studies using both radiotracers. Biodistribution study using Tc-99m tin colloid revealed increased lung radioactivity in thioacetamide-treated mice. Twenty-four hours after thioacetamide administration, thioacetamide-treated rats demonstrated maximal hepatocyte necrosis and inflammation in histologic finding and delayed maximal uptake time (Tmax) and prolonged half time (T 1/2 ) of liver time-activity curve in liver scintigraphy. Histologic results and scintigraphic data were well correlated, and these two scintigraphic parameters (Tmax T 1/2 ) seemed to be good predictors of histologic change of liver. These data showed that liver injury could be assessed by non-invasive scintigraphic study in rat and mouse. This experimental study might be used as a animal model to evaluate the liver protecting drugs, and this scintigraphic study could be applied to acute toxic hepatitis for assessment of liver status in men

  11. XV ESLAB Symposium

    CERN Document Server

    1981-01-01

    The 15th ESLAB symposium was held at the end of June 1981 in Amsterdam with the topic being X-ray astronomy. The aim of this symposium was to bring together the international astrophysical community in order to 1. review the present state of X-ray astronomy in the light of new observations gathered in recent missions and to review data on interesting objects in correlated wavelen8th regions; 2. discuss theoretical models describing the phenomena observed; 3. present ESA's European X-ray Observatory Satellite (EXOSAT) and to discuss future X-ray missions and their associated instrumenta­ tion. These topics seemed to be so interesting for the scientific community that more than 120 contributions were submitted. Of these, 94 were finally accepted and approximately 200 participants attended the 5-day meeting. The symposium was organised in nine sessions covering the whole field. Every main topic was introduced by a review lecture covering the state­ of-the-art. The aim of the meeting was to assess the impact of...

  12. Human Induced Pluripotent Stem Cell-Derived Macrophages Share Ontogeny with MYB-Independent Tissue-Resident Macrophages

    Directory of Open Access Journals (Sweden)

    Julian Buchrieser

    2017-02-01

    Full Text Available Tissue-resident macrophages, such as microglia, Kupffer cells, and Langerhans cells, derive from Myb-independent yolk sac (YS progenitors generated before the emergence of hematopoietic stem cells (HSCs. Myb-independent YS-derived resident macrophages self-renew locally, independently of circulating monocytes and HSCs. In contrast, adult blood monocytes, as well as infiltrating, gut, and dermal macrophages, derive from Myb-dependent HSCs. These findings are derived from the mouse, using gene knockouts and lineage tracing, but their applicability to human development has not been formally demonstrated. Here, we use human induced pluripotent stem cells (iPSCs as a tool to model human hematopoietic development. By using a CRISPR-Cas9 knockout strategy, we show that human iPSC-derived monocytes/macrophages develop in an MYB-independent, RUNX1-, and SPI1 (PU.1-dependent fashion. This result makes human iPSC-derived macrophages developmentally related to and a good model for MYB-independent tissue-resident macrophages, such as alveolar and kidney macrophages, microglia, Kupffer cells, and Langerhans cells.

  13. Spin symposium

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1989-01-15

    The recent 8th International Symposium on High Energy Spin Physics at the University of Minnesota in Minneapolis, Minnesota, opened with a bang when L. Pondrom (Wisconsin), donning a hard hat borrowed from construction workers, ventured that 'spin, the notorious inessential complication of hadronic physics, is finally telling us what real QCD (quantum chromodynamics, the field theory of quarks and gluons) looks like.' He was referring to an animated discussion on the meaning of the recent spin oriented (polarized) scattering results from the European Muon Collaboration (EMC) at CERN and reported at the Symposium by R. Garnet (Liverpool) and P. Schuler (Yale) which show that the proton spin is not simply a reflection of the spins of its constituent quarks.

  14. 43rd Aerospace Mechanisms Symposium

    Science.gov (United States)

    Boesiger, Edward A.

    2016-01-01

    The Aerospace Mechanisms Symposium (AMS) provides a unique forum for those active in the design, production and use of aerospace mechanisms. A major focus is the reporting of problems and solutions associated with the development and flight certification of new mechanisms. Sponsored and organized by the Mechanisms Education Association, responsibility for hosting the AMS is shared by the National Aeronautics and Space Administration and Lockheed Martin Space Systems Company (LMSSC). Now in its 43rd symposium, the AMS continues to be well attended, attracting participants from both the U.S. and abroad. The 43rd AMS was held in Santa Clara, California on May 4, 5 and 6, 2016. During these three days, 42 papers were presented. Topics included payload and positioning mechanisms, components such as hinges and motors, CubeSats, tribology, and mechanism testing. Hardware displays during the supplier exhibit gave attendees an opportunity to meet with developers of current and future mechanism components. The high quality of this symposium is a result of the work of many people, and their efforts are gratefully acknowledged. This extends to the voluntary members of the symposium organizing committee representing the eight NASA field centers, LMSSC, and the European Space Agency. Appreciation is also extended to the session chairs, the authors, and particularly the personnel at ARC responsible for the symposium arrangements and the publication of these proceedings. A sincere thank you also goes to the symposium executive committee who is responsible for the year-to-year management of the AMS, including paper processing and preparation of the program. The use of trade names of manufacturers in this publication does not constitute an official endorsement of such products or manufacturers, either expressed or implied, by the National Aeronautics and Space Administration.

  15. Proceedings of the symposium on networking

    International Nuclear Information System (INIS)

    Karita, Yukio; Abe, Fumio

    1989-06-01

    The first symposium on networking was held on February 6-7, 1989. Due to the increase of the needs of computer networks, several networks which connect among universities and laboratories are going to be constructed in Japan. However, the techniques in networking are not familiar to most people, and the information about these techniques is sometimes difficult to get, especially in multivendor connection. In such situation, an opportunity to hold a symposium on networking at the National Laboratory for High Energy Physics (KEK) was given. More than 200 people took part in this symposium, and the local area networks in institutions, the networks among institutions, the networks for high energy physics, the application of networks, the networks for academic research and so on are reported. The valuable discussion about networks was carried out, including the plans for near future. At the time of this symposium, the construction of the Gakujo-net and the Pacific network project of University of Hawaii were in progress, and many Japanese universities are going to construct their campus LANs, so the symposium seemed to be very timely. (K.I.)

  16. 6th interventional MRI symposium. Abstracts

    International Nuclear Information System (INIS)

    2006-01-01

    The ongoing progress in the field of interventional MRI and the great success of our last symposium 2004 in Boston have stimulated us to organize the 6th Interventional MRI Symposium to be held September 15-16, 2006 in Leipzig. This meeting will highlight ground-breaking research as well as cutting-edge reports from many groups. The symposium also provides a forum to network with leaders and innovators in the field. Session topics are: intraoperative MRI, vascular applications, targeted drug delivery, cryotherapy, thermometry, pulse sequences, LITT, percutaneous procedures, navigation, robotics, focused ultrasound. (uke)

  17. Toward human organ printing: Charleston Bioprinting Symposium.

    Science.gov (United States)

    Mironov, Vladimir

    2006-01-01

    The First Annual Charleston Bioprinting Symposium was organized by the Bioprinting Research Center of the Medical University of South Carolina (MUSC) and convened July 21, 2006, in Charleston, South Carolina. In broad terms, bioprinting is the application of rapid prototyping technology to the biomedical field. More specifically, it is defined as the layer by layer deposition of biologically relevant material. The 2006 Symposium included four sessions: Computer-aided design and Bioprinting, Bioprinting Technologies; Hydrogel for Bioprinting and, finally, a special session devoted to ongoing research projects at the MUSC Bioprinting Research Center. The Symposium highlight was the presentation of the multidisciplinary Charleston Bioengineered Kidney Project. This symposium demonstrated that bioprinting or robotic biofabrication is one of the most exciting and fast-emerging branches in the tissue engineering field. Robotic biofabrication will eventually lead to industrial production of living human organs suitable for clinical transplantation. The symposium demonstrated that although there are still many technological challenges, organ printing is a rapidly evolving feasible technology.

  18. The proceedings of the Tenth Symposium on Lactic Acid Bacteria

    NARCIS (Netherlands)

    Hill, Colin; Kleerebezem, Michiel; Kok, Jan

    2011-01-01

    We were delighted to be asked by Microbial Cell Factories to act as guest editors for the manuscripts in this issue associated with the LAB10 Symposium. The LAB Sympo- sia have been very important benchmarks in the careers of many LAB researchers, charting the development of this field from the very

  19. Summary Report on the SAE 2016 Range Extenders for Electric Vehicles Symposium

    Energy Technology Data Exchange (ETDEWEB)

    Curran, Scott [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Wagner, Robert M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Campbell, Russ [SRA International, Inc., Arlington, VA (United States)

    2017-03-01

    The SAE 2016 Range Extenders for Electric Vehicles Symposium was a 2-day technical meeting focused on the role of advanced internal combustion engines (ICEs) and other novel energy converter technologies for extending the range of electric vehicles (EVs). The first-of-its-kind symposium was notable for focusing solely on the range extender (REx) technologies and not the EVs. The technical program featured presentations from international leaders from industry, government, national laboratories, and academia. The opening keynote presentations covered a broad range of topics including consumer behavior, policy implications, regulatory considerations, and REx architectures as enablers for advanced technologies. The technical sessions focused on an array of REx technologies including conventional ICEs, as well as less conventional or emerging technologies such as microturbines, fuel cells, low-temperature combustion engines, and aluminum-air batteries. The symposium included two panel sessions. The trend toward increasing vehicle electrification and the changing role of ICEs and other auxiliary power unit technologies for use as REx’s is leading to new research and design development needs. The symposium captured the interest of the industry and research communities in exploring the opportunities and challenges associated with REx’s for EVs. This report includes key takeaways, summarized below, and draft notes for each presentation and panel discussion.

  20. 4th International Language Management Symposium

    Czech Academy of Sciences Publication Activity Database

    Prošek, Martin

    2016-01-01

    Roč. 77, č. 3 (2016), s. 233-240 ISSN 0037-7031. [international language management symposium] Institutional support: RVO:68378092 Keywords : language management theory * international language symposium * language management Subject RIV: AI - Linguistics OBOR OECD: Linguistics Impact factor: 0.625, year: 2016

  1. CONFERENCE NOTE: Sixth Symposium on Temperature Scheduled for March 1982

    Science.gov (United States)

    1981-07-01

    The call for papers for the 6th Symposium on Temperature, Its Measurement and Control in Science and Industry has been issued. The Symposium is scheduled to take place in Washington, DC, USA during the week of March 14 18, 1982. Like its predecessors held in the years 1919, 1939, 1954, 1961, and 1971, the 6th Symposium will stress advances in the measurement of thermodynamic values of temperature, in temperature reference points, in temperature sensors and instruments for the control of temperature, and in the development and use of temperature scales. For the first time, an exhibit of thermometry will be a part of the Symposium. Manuscripts to be submitted for inclusion in the Symposium should be sent to the 6th Temperature Symposium Program Chairman, National Bureau of Standards, by September 15, 1981. Those papers accepted for the Symposium will be due in camera-ready form by February 15, 1982. Original papers on all of the topics listed above, as well as reviews of the past decade's progress in thermometry and temperature control, are solicited by the Symposium organizers. The Symposium arrangements and registration are in the care of the Instrument Society of America (represented on the Symposium General Committee by Mr C T Glazer, 67 Alexander Drive, PO Box 12277, Research Triangle Park, North Carolina, 27709, USA). Questions regarding the instrument exhibits should also be addressed to the ISA. The technical program for the Symposium is the responsibility of a committee headed by Dr J F Schooley, Room B-128 Physics Building, National Bureau of Standards, Washington, DC, 20234, USA. The Symposium proceedings will be published by the American Institute of Physics.

  2. Welcome and introduction to symposium

    OpenAIRE

    humanities, Symposium on Information and technology in the arts and; McLaughlin, Jeremy Lee; Matusiak, Krystyna; Hirsh, Sandra

    2015-01-01

    Welcome and introduction slides used for presentation at the Virtual Symposium on Information and Technology in the Arts and Humanities, held April 22 and 23, 2015. The Symposium was co-sponsored by the ASIS&T (Association for Information Science and Technology) Special Interest Group for Arts and Humanities (SIG AH) and the Special Interest Group for Visualization, Images, and Sound (SIG VIS).

  3. A primary study on the phagocytic activity of Kupffer cells with superparamagnetic iron oxide particles enhanced MR imaging in a rat nonalcoholic steatohepatitis model

    International Nuclear Information System (INIS)

    Jiao Zhiyun; Li Cheng; Ma Zhanlong; Chen Wenjuan

    2010-01-01

    Objective: To investigate the feasibility of using superparamgnetic iron oxide (SPIO) as MRI contrast agent to assess rat nonalcoholic steatohepatitis Kupffer cells (KC) function. Methods: Twenty male SD rats were randomly divided into A and B groups, group A (n=10) was the experimental group fed high fat diet, group B (n=10) was the control group fed normal diet. After 8 weeks, plain MR and SPIO enhanced MR were performed in all the rats. Blood lipids were measured, and HE and Perl's blue staining in all livers specimen was done. The related results of the staining were analyzed with t test. Results: Group A TC and TG levels [(6.58 ± 1.25) and (1.53 ± 0.23) mmol/L respectively] were significantly higher than group B[(1.64 ± 0.22) and (0.55 ± 0.14) mmol/L respectively] (t=11.716 and 11.588, P 1 WI, ad statistically significant differences (t=-18.451 and -16.240, P 2 WI, T 2 WI and T 1 WI (t=10.745, 19.800, 39.168 and 92.785, P<0.01). Typical histological hepatic lesions of NASH were observed in group A, Perl's staining-positive particles in group A (2.33 ± 0.50) were fewer than in group B (4) (t=-10.000, P<0.01). Conclusion: The high-fat diet induced model of SD rats was close to the human NASH and was easy to establish. Clinical application of SPIO enhanced MR successfullly assessed the phagocytic activity of KC in the study, and it suggested that the pathogenesis of NASH was related to the decreased phagocytic activity of KC. (authors)

  4. 10th German nuclear law symposium

    International Nuclear Information System (INIS)

    Koch, H.J.; Rossnagel, A.

    2000-01-01

    This 10th symposium on nuclear law in Germany was held eight years after the 9th symposium. Due to the change of government after the last general elections, there had been a turnaround in Germany's energy policy. 'Phasing out nuclear energy' was the major strategy of the new Federal Government. The topics of the papers presented at the symposium therefore focus on: a new time frame for NPP shutdown and termination of operating licences; ensuring the safe operation of nuclear power plants for the remaining operating periods; new concepts for radwaste management and ultimate disposal. (orig./CB) [de

  5. Proceedings of the seventh symposium on laser spectroscopy

    International Nuclear Information System (INIS)

    1999-01-01

    This proceedings contains articles of the 7th symposium on laser spectroscopy and this symposium is held on Nov. 5-6, 1999 by KAERI. Both the laser and laser beams are critically used in many most precise measurements in science and technology. We discussed about the recently developed subjects in detail during the this symposium. This proceedings is composed of two major parts. One is the invitational lectures and the other is the research papers. And we have a number of invited speakers from several advanced countries. Their talks are the highlights of this symposium. (Cho, G. S.)

  6. Proceedings of the eighth symposium on laser spectroscopy

    International Nuclear Information System (INIS)

    2000-01-01

    This proceedings contains articles of the 8th symposium on laser spectroscopy and this symposium is held on Nov. 3-4, 2000 by KAERI. Both the laser and laser beams are critically used in many most precise measurements in science and technology. We discussed about the recently developed subjects in detail during the this symposium. This proceedings is composed of two major parts. One is the invitational lectures and the other is the research papers. And we have a number of invited speakers from several advanced countries. Their talks are the highlights of this symposium. (Yi, J. H.)

  7. International symposium 'Energetics 2004'. Symposium proceedings. Book 1

    International Nuclear Information System (INIS)

    2004-01-01

    The holding of this Symposium was initiated by ZEMAK - Macedonian Energy Association that for the last tens of years established itself in the national and international scientific and professional circles as a competent association of professionals with the main goal to follow, promote and improve the energy sector in the country. Having in mind the fact that the power energy sector as a fundamental sector plays a main role in the development and the improvement of the rest of the industry, and in the same time has a tremendous impact on the sustainable development of the entire economy of a country, power energy sector in fact has the paramount importance in the business environment of our country. Thus, ZEMAK has historically important role as a responsible and permanent driver, promoter and initiator for resolving of all-important questions directly or indirectly interconnected with the power energy sector in the country, and therefore the entire economy in the country as well. Following the past, ZEMAK had and would always have needs of organizing national and international symposiums and workshops as a panel where directly at one place national and international power energy experts could initiate, debate and resolve all up-to-date questions in the present energy sector in Macedonia, could analyze the modern world trends in the energy sector and try to find appropriate models for their application for further development and improvement of the energy sector in our country. This international symposium has the main goal to concentrate on a single place everybody who has power energy as a permanent preoccupation and/or vocation and professional interest. To aggregate on one place various experts, from the Academy and Universities, from the business circles and companies who are preoccupied with power energy directly or indirectly in their everyday life and work. During the Symposium more than 90 scientific and/or professional papers were presented and discussed

  8. International symposium 'Energetics 2004'. Symposium proceedings. Book 2

    International Nuclear Information System (INIS)

    2004-01-01

    The holding of this Symposium was initiated by ZEMAK - Macedonian Energy Association that for the last tens of years established itself in the national and international scientific and professional circles as a competent association of professionals with the main goal to follow, promote and improve the energy sector in the country. Having in mind the fact that the power energy sector as a fundamental sector plays a main role in the development and the improvement of the rest of the industry, and in the same time has a tremendous impact on the sustainable development of the entire economy of a country, power energy sector in fact has the paramount importance in the business environment of our country. Thus, ZEMAK has historically important role as a responsible and permanent driver, promoter and initiator for resolving of all-important questions directly or indirectly interconnected with the power energy sector in the country, and therefore the entire economy in the country as well. Following the past, ZEMAK had and would always have needs of organizing national and international symposiums and workshops as a panel where directly at one place national and international power energy experts could initiate, debate and resolve all up-to-date questions in the present energy sector in Macedonia, could analyze the modern world trends in the energy sector and try to find appropriate models for their application for further development and improvement of the energy sector in our country. This international symposium has the main goal to concentrate on a single place everybody who has power energy as a permanent preoccupation and/or vocation and professional interest. To aggregate on one place various experts, from the Academy and Universities, from the business circles and companies who are preoccupied with power energy directly or indirectly in their everyday life and work. During the Symposium more than 90 scientific and/or professional papers were presented and discussed

  9. LHC Nobel Symposium Proceedings

    Science.gov (United States)

    Ekelöf, Tord

    2013-12-01

    In the summer of 2012, a great discovery emerged at the Large Hadron Collider (LHC) at CERN in Geneva. A plethora of new precision data had already by then been collected by the ATLAS and CMS experiments at LHC, providing further extensive support for the validity of the Standard Model of particle physics. But what now appeared was the first evidence for what was not only the last unverified prediction of the Standard Model, but also perhaps the most decisive one: the prediction made already in 1964 of a unique scalar boson required by the theory of François Englert and Peter Higgs on how fundamental particles acquire mass. At that moment in 2012, it seemed particularly appropriate to start planning a gathering of world experts in particle physics to take stock of the situation and try to answer the challenging question: what next? By May 2013, when the LHC Nobel Symposium was held at the Krusenberg Mansion outside Uppsala in Sweden, the first signs of a great discovery had already turned into fully convincing experimental evidence for the existence of a scalar boson of mass about 125 GeV, having properties compatible with the 50-year-old prediction. And in October 2013, the evidence was deemed so convincing that the Swedish Royal Academy of Sciences awarded the Nobel Prize in Physics to Englert and Higgs for their pioneering work. At the same time the search at the LHC for other particles, beyond those predicted by the Standard Model, with heavier masses up to—and in some cases beyond—1 TeV, had provided no positive result. The triumph of the Standard Model seems resounding, in particular because the mass of the discovered scalar boson is such that, when identified with the Higgs boson, the Standard Model is able to provide predictions at energies as high as the Planck mass, although at the price of accepting that the vacuum would be metastable. However, even if there were some feelings of triumph, the ambience at the LHC Nobel Symposium was more one of

  10. Identification of Adenovirus Serotype 5 Hexon Regions That Interact with Scavenger Receptors

    Energy Technology Data Exchange (ETDEWEB)

    Khare, Reeti; Reddy, Vijay S.; Nemerow, Glen R.; Barry, Michael A. (Scripps); (Mayo)

    2012-05-04

    Most of an intravenous dose of species C adenovirus serotype 5 (Ad5) is destroyed by liver Kupffer cells. In contrast, another species C virus, Ad6, evades these cells to mediate more efficient liver gene delivery. Given that this difference in Kupffer cell interaction is mediated by the hypervariable (HVR) loops of the virus hexon protein, we genetically modified each of the seven HVRs of Ad5 with a cysteine residue to enable conditional blocking of these sites with polyethylene glycol (PEG). We show that these modifications do not affect in vitro virus transduction. In contrast, after intravenous injection, targeted PEGylation at HVRs 1, 2, 5, and 7 increased viral liver transduction up to 20-fold. Elimination or saturation of liver Kupffer cells did not significantly affect this increase in the liver transduction. In vitro, PEGylation blocked uptake of viruses via the Kupffer cell scavenger receptor SRA-II. These data suggest that HVRs 1, 2, 5, and 7 of Ad5 may be involved in Kupffer cell recognition and subsequent destruction. These data also demonstrate that this conditional genetic-chemical mutation strategy is a useful tool for investigating the interactions of viruses with host tissues.

  11. The Abel Symposium 2013

    CERN Document Server

    Irgens, Marius; Wold, Erlend

    2015-01-01

    This book focuses on complex geometry and covers highly active topics centered around geometric problems in several complex variables and complex dynamics, written by some of the world’s leading experts in their respective fields. This book features research and expository contributions from the 2013 Abel Symposium, held at the Norwegian University of Science and Technology Trondheim on July 2-5, 2013. The purpose of the symposium was to present the state of the art on the topics, and to discuss future research directions.

  12. 2016 AMS Mario J. Molina Symposium

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Renyi [Texas A & M Univ., College Station, TX (United States)

    2016-11-29

    A named symposium to honor Dr. Mario J. Molina was held 10–14 January 2016, as part of the 96th American Meteorological Society (AMS) Annual Meeting in New Orleans, Louisiana. Dr. Molina first demonstrated that industrially produced chlorofluorocarbons (CFCs) decompose in the stratosphere and release chlorine atoms, leading to catalytic ozone destruction. His research in stratospheric chemistry was instrumental to the establishment of the 1987 United Nations Montreal Protocol to ban ozone-depleting substances worldwide. Dr. Molina’s contributions to preserving the planet Earth not only save the atmospheric ozone layer, but also protect the climate by reducing the emissions of greenhouse gases. He was awarded the 1995 Nobel Prize in Chemistry for his pioneering research in understanding the stratospheric ozone loss mechanism. In 2013, President Barack Obama announced Dr. Molina as a recipient of the Presidential Medal of Freedom. The 2016 AMS Molina Symposium honored Dr. Molina’s distinguished contributions to research related to atmospheric chemistry. The symposium contained an integrated theme related to atmospheric chemistry, climate, and policy. Dr. Molina delivered a keynote speech at the Symposium. The conference included invited keynote speeches and invited and contributed oral and poster sessions, and a banquet was held on Tuesday January 12, 2016. The symposium covered all aspects of atmospheric chemistry, with topics including (1) Stratospheric chemistry, (2) Tropospheric chemistry, (3) Aerosol nucleation, growth, and transformation, (4) Aerosol properties, (5) Megacity air pollution, and (6) Atmospheric chemistry laboratory, field, and modeling studies. This DOE project supported 14 scientists, including graduate students, post docs, junior research scientists, and non-tenured assistant professors to attend this symposium.

  13. Memorial Symposium for Willibald Jentschke

    CERN Multimedia

    2002-01-01

    Willibald 'Willi' Jentschke, Director General of CERN from 1971 to 1975 and founder of the DESY Laboratory in Hamburg, died last March, just a few months after celebrating his 90th birthday. At that time, the Bulletin dedicated an article to him (Bulletin n°19-20/2002). Now, CERN has organised a Memorial Symposium for next Thursday 31 October, where you are cordially invited. This tribute will include the following speechs: L. Maiani : Welcome E. Lohrmann : Message from DESY H. Schopper : Willi Jentschke M. Veltman and D. Perkins : The Neutral Currents K. Johnsen : The ISR in Jentschke's time K. Winter : Some recollections of Jentschke The Memorial Symposium will take place in the Council Chamber, Thursday 31 October at 15 hrs. Drinks will be served at 17:30 hrs following the symposium.

  14. A Symposium.

    Science.gov (United States)

    Rachal, John R.

    2003-01-01

    Uses the framework of a symposium to present an imagined discussion by historical figures about whether and how knowledge might be acquired. Discussants include Democritus, Protagoras, Heraclitus, Socrates, Jesus, Gorgias, Nietzsche, Buddha, and Kierkegaard. (Contains 40 endnotes.) (SK)

  15. India Symposium

    Indian Academy of Sciences (India)

    JNCASR

    Impact of Women's research in Science and Technology in the new millennium'. The. Symposium will showcase the work done by young Indian Women Scientists in different branches of Science and Engineering, at a wide spectrum of Research ...

  16. Kupffer's vesicle is a ciliated organ of asymmetry in the zebrafish embryo that initiates left-right development of the brain, heart and gut.

    Science.gov (United States)

    Essner, Jeffrey J; Amack, Jeffrey D; Nyholm, Molly K; Harris, Erin B; Yost, H Joseph

    2005-03-01

    Monocilia have been proposed to establish the left-right (LR) body axis in vertebrate embryos by creating a directional fluid flow that triggers asymmetric gene expression. In zebrafish, dorsal forerunner cells (DFCs) express a conserved ciliary dynein gene (left-right dynein-related1, lrdr1) and form a ciliated epithelium inside a fluid-filled organ called Kupffer's vesicle (KV). Here, videomicroscopy demonstrates that cilia inside KV are motile and create a directional fluid flow just prior to the onset of asymmetric gene expression in lateral cells. Laser ablation of DFCs and surgical disruption of KV provide direct evidence that ciliated KV cells are required during early somitogenesis for subsequent LR patterning in the brain, heart and gut. Antisense morpholinos against lrdr1 disrupt KV fluid flow and perturb LR development. Furthermore, lrdr1 morpholinos targeted to DFC/KV cells demonstrate that Lrdr1 functions in these ciliated cells to control LR patterning. This provides the first direct evidence, in any vertebrate, that impairing cilia function in derivatives of the dorsal organizer, and not in other cells that express ciliogenic genes, alters LR development. Finally, genetic analysis reveals novel roles for the T-box transcription factor no tail and the Nodal signaling pathway as upstream regulators of lrdr1 expression and KV morphogenesis. We propose that KV is a transient embryonic 'organ of asymmetry' that directs LR development by establishing a directional fluid flow. These results suggest that cilia are an essential component of a conserved mechanism that controls the transition from bilateral symmetry to LR asymmetry in vertebrates.

  17. 6th International Symposium on Molecular Allergology (ISMA)

    OpenAIRE

    Hilger, Christiane; Swiontek, Kyra; Fischer, J?rg; Hentges, Fran?ois; Lehners, Christiane; Morisset, Martine; Eberlein, Bernadette; Biedermann, Tilo; Ollert, Markus; Wildner, Sabrina; Stemeseder, Teresa; Freier, Regina; Briza, Peter; Lang, Roland; Batanero, Eva

    2016-01-01

    Table of contents ORAL ABSTRACTS Symposium 1: Biochemistry, structure and environment of the allergen: what makes a protein an allergen? O1 Two cell-membrane peptidases carrying galactose-alpha-1,3-galactose are implicated in delayed anaphylactic reactions upon pork kidney ingestion in patients with IgE-antibodies to alpha-Gal Christiane Hilger, Kyra Swiontek, Jörg Fischer, François Hentges, Christiane Lehners, Martine Morisset, Bernadette Eberlein, Tilo Biedermann, Markus Ollert O2 Structure...

  18. 1984 Statistical symposium on national energy issues: proceedings

    International Nuclear Information System (INIS)

    Kinnison, R.; Doctor, P.

    1985-07-01

    The 1984 Statistical Symposium on National Energy Issues was the tenth in a series of annual symposia bringing together statisticians and other interested parties who are actively engaged in the pursuit of solving the nation's energy problems. Initially the symposium was sponsored by US Department of Energy (DOE) and named the DOE Statistical Symposium. The symposium is organized by a steering committee made up of representatives from the national laboratories. The 1984 symposium was hosted by Pacific Northwest Laboratory, and it was organized around four special topical sessions: (1) assessing and assuring high reliability, (2) spatial statistical, (3) quantification of informed opinion, and (4) health effects of energy technologies. These were chosen by the steering committee as topics currently of high importance in energy research and data analysis. Several contributed papers were also presented. Separate abstracts have been prepared for 17 papers for inclusion in the Energy Data Base

  19. International symposium 'Energetics 2006'. Symposium proceedings

    International Nuclear Information System (INIS)

    2006-01-01

    ZEMAK as a civil association, created in the term positive legitimate regulations of our country, presents non party, non political and non profitable association, which primary goal is animation of eperts and other scientific and non scientific workers in the function of permanent following, studying and giving directives for solve the energy problems for a long temporal period. Behind us are fourteen successful years of fertile and wealthy work, which is bringing maimal penetration in domestic as well as foreign scientific field. This successful work of ZEMAK deserves by all members which professional work is in the institutions like: MANU (Macedonian academy of science and art), Technical faculties from the Universities, state and private company from energy field and other civil persons. The main goal of this 9-th International Symposium traditionally is to collect all engineers and eperts from the field of energy, and those which professional life is energy. During this International Symposium will be present, analyze and discuss about 100 incoming papers, prepared by 100th or more authors and coauthors, divided in the following topics: Basic energy and ecology, Renewable energy sources, Energy efficiency and energy saving and Management in energy and regulations.

  20. Space 2000 Symposium

    Science.gov (United States)

    1999-01-01

    The purpose of the Space 2000 Symposium is to present the creativity and achievements of key figures of the 20th century. It offers a retrospective discussion on space exploration. It considers the future of the enterprise, and the legacy that will be left for future generations. The symposium includes panel discussions, smaller session meetings with some panelists, exhibits, and displays. The first session entitled "From Science Fiction to Science Facts" commences after a brief overview of the symposium. The panel discussions include talks on space exploration over many decades, and the missions of the millennium to search for life on Mars. The second session, "Risks and Rewards of Human Space Exploration," focuses on the training and health risks that astronauts face on their exploratory mission to space. Session three, "Messages and Messengers Informing and Inspire Space Exploration and the Public," focuses on the use of TV medium by educators and actors to inform and inspire a wide variety of audiences with adventures of space exploration. Session four, "The Legacy of Carl Sagan," discusses the influences made by Sagan to scientific research and the general public. In session five, "Space Exploration for a new Generation," two student speakers and the NASA Administrator Daniel S. Goldin address the group. Session six, "Destiny or Delusion? -- Humankind's Place in the Cosmos," ends the symposium with issues of space exploration and some thought provoking questions. Some of these issues and questions are: what will be the societal implications if we discover the origin of the universe, stars, or life; what will be the impact if scientists find clear evidence of life outside the domains of the Earth; should there be limits to what humans can or should learn; and what visionary steps should space-faring people take now for future generations.

  1. COMPUTING: International symposium

    International Nuclear Information System (INIS)

    Anon.

    1984-01-01

    Recent Developments in Computing, Processor, and Software Research for High Energy Physics, a four-day international symposium, was held in Guanajuato, Mexico, from 8-11 May, with 112 attendees from nine countries. The symposium was the third in a series of meetings exploring activities in leading-edge computing technology in both processor and software research and their effects on high energy physics. Topics covered included fixed-target on- and off-line reconstruction processors; lattice gauge and general theoretical processors and computing; multiprocessor projects; electron-positron collider on- and offline reconstruction processors; state-of-the-art in university computer science and industry; software research; accelerator processors; and proton-antiproton collider on and off-line reconstruction processors

  2. 6{sup th} interventional MRI symposium. Abstracts

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    The ongoing progress in the field of interventional MRI and the great success of our last symposium 2004 in Boston have stimulated us to organize the 6th Interventional MRI Symposium to be held September 15-16, 2006 in Leipzig. This meeting will highlight ground-breaking research as well as cutting-edge reports from many groups. The symposium also provides a forum to network with leaders and innovators in the field. Session topics are: intraoperative MRI, vascular applications, targeted drug delivery, cryotherapy, thermometry, pulse sequences, LITT, percutaneous procedures, navigation, robotics, focused ultrasound. (uke)

  3. The fifth Finnish national aerosol symposium

    International Nuclear Information System (INIS)

    Mikkanen, P.; Haemeri, K.; Kauppinen, E.

    1993-01-01

    The Fifth Finnish Aerosol Symposium was held June 1-3, 1993. Symposium is jointly organized by FAAR, Aerosol Technology Group of Technical Research Centre of Finland and Helsinki University, Department of Physics. Aerosols, the suspensions of solid and liquid particles and gases, are receiving increasing importance in many areas of science and technology. These include industrial hygiene, ambient and indoor air pollution, pollution control technologies, cloud physics, nuclear safety engineering, combustion science and engineering, clean manufacturing technologies and material processing. The importance of aerosol issues during the development of advanced fuel conversion and material processing technologies can be realized when looking at the numerous papers presented on these topics at the Symposium

  4. IUTAM Symposium

    CERN Document Server

    Stefanou, George

    2014-01-01

    This book contains the proceedings of the IUTAM Symposium on Multiscale Modeling and Uncertainty Quantification of Materials and Structures that was held at Santorini, Greece, September 9 – 11, 2013. It consists of 20 chapters which are divided in five thematic topics: Damage and fracture, homogenization, inverse problems–identification, multiscale stochastic mechanics and stochastic dynamics. Over the last few years, the intense research activity at microscale and nanoscale reflected the need to account for disparate levels of uncertainty from various sources and across scales. As even over-refined deterministic approaches are not able to account for this issue, an efficient blending of stochastic and multiscale methodologies is required to provide a rational framework for the analysis and design of materials and structures. The purpose of this IUTAM Symposium was to promote achievements in uncertainty quantification combined with multiscale modeling and to encourage research and development in this grow...

  5. The 20th Hadron Collider Physics Symposium in Evian

    CERN Multimedia

    Ludwik Dobrzynski and Emmanuel Tsesmelis

    The 20th Hadron Collider Physics Symposium took place in Evian from 16 to 20 November 2009. The Hadron Collider Physics Symposium series has been a major forum for presentations of physics at the Tevatron over the past two decades. The merger of the former Topical Conference on Hadron Collider Physics with the LHC Symposium in 2005 brought together the Tevatron and LHC communities in a single forum. The 20th Hadron Collider Physics Symposium took place in Evian, on the shores of Lake Geneva, from 16-20 November 2009, some 17 years after the historic ECFA-CERN Evian meeting in March 1992 when Expressions of Interest for LHC detectors were presented for the first time. The 2009 event was organized jointly by CERN and the French high-energy physics community (CNRS-IN2P3 and CEA-IRFU). More than 170 people registered for this symposium. This year’s symposium was held at an important time for both the Tevatron and the LHC. It stimulated the completion of analyses for a significant Tevatron data sam...

  6. Coal economics and taxation discussed at symposium

    Energy Technology Data Exchange (ETDEWEB)

    1978-06-01

    Some of the highlights from the Symposium on Coal Economics and Taxation Symposium, Regina Saskatchewan May 7-9, 1978, sponsored by the Coal Association of Canada are presented. Investment, provincial policy, sources of funds, uncertainty, tax policies, and operating costs are discussed.

  7. Oxidative and ER stress-dependent ASK1 activation in steatotic hepatocytes and Kupffer cells sensitizes mice fatty liver to ischemia/reperfusion injury.

    Science.gov (United States)

    Imarisio, Chiara; Alchera, Elisa; Bangalore Revanna, Chandrashekar; Valente, Guido; Follenzi, Antonia; Trisolini, Elena; Boldorini, Renzo; Carini, Rita

    2017-11-01

    Steatosis intensifies hepatic ischemia/reperfusion (I/R) injury increasing hepatocyte damage and hepatic inflammation. This study evaluates if this process is associated to a differential response of steatotic hepatocytes (HP) and Kupffer cells (KC) to I/R injury and investigates the molecular mechanisms involved. Control or steatotic (treated with 50 μmol palmitic acid, PA) mouse HP or KC were exposed to hypoxia/reoxygenation (H/R). C57BL/6 mice fed 9 week with control or High Fat diet underwent to partial hepatic IR. PA increased H/R damage of HP and further activated the ASK1-JNK axis stimulated by ER stress during H/R. PA also induced the production of oxidant species (OS), and OS prevention nullified the capacity of PA to increase H/R damage and ASK1/JNK stimulation. ASK1 inhibition prevented JNK activation and entirely protected HP damage. In KC, PA directly activated ER stress, ASK1 and p38 MAPK and increased H/R damage. However, in contrast to HP, ASK1 inhibition further increased H/R damage by preventing p38 MAPK activation. In mice liver, steatosis induced the expression of activated ASK1 in only KC, whereas I/R exposure of steatotic liver activated ASK1 expression also in HP. "In vivo", ASK1 inhibition prevented ASK1, JNK and p38 MAPK activation and protected I/R damage and expression of inflammatory markers. Lipids-induced ASK1 stimulation differentially affects HP and KC by promoting cytotoxic or protective signals. ASK1 increases H/R damage of HP by stimulating JNK and protects KC activating p38MAPK. These data support the potentiality of the therapeutic employment of ASK1 inhibitors that can antagonize the damaging effects of I/R upon fatty liver surgery by the contextual reduction of HP death and of KC-mediated reactions. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. Symposium on unsaturated flow and transport modeling

    International Nuclear Information System (INIS)

    Arnold, E.M.; Gee, G.W.; Nelson, R.W.

    1982-09-01

    This document records the proceedings of a symposium on flow and transport processes in partially saturated groundwater systems, conducted at the Battelle Seattle Research Center on March 22-24, 1982. The symposium was sponsored by the US Nuclear Regulatory Commission for the purpose of assessing the state-of-the-art of flow and transport modeling for use in licensing low-level nuclear waste repositories in partially saturated zones. The first day of the symposium centered around research in flow through partially saturated systems. Papers were presented with the opportunity for questions following each presentation. In addition, after all the talks, a formal panel discussion was held during which written questions were addressed to the panel of the days speakers. The second day of the Symposium was devoted to solute and contaminant transport in partially saturated media in an identical format. Individual papers are abstracted

  9. Symposium on unsaturated flow and transport modeling

    Energy Technology Data Exchange (ETDEWEB)

    Arnold, E.M.; Gee, G.W.; Nelson, R.W. (eds.)

    1982-09-01

    This document records the proceedings of a symposium on flow and transport processes in partially saturated groundwater systems, conducted at the Battelle Seattle Research Center on March 22-24, 1982. The symposium was sponsored by the US Nuclear Regulatory Commission for the purpose of assessing the state-of-the-art of flow and transport modeling for use in licensing low-level nuclear waste repositories in partially saturated zones. The first day of the symposium centered around research in flow through partially saturated systems. Papers were presented with the opportunity for questions following each presentation. In addition, after all the talks, a formal panel discussion was held during which written questions were addressed to the panel of the days speakers. The second day of the Symposium was devoted to solute and contaminant transport in partially saturated media in an identical format. Individual papers are abstracted.

  10. IAEA symposium on international safeguards

    International Nuclear Information System (INIS)

    1999-01-01

    The eighth IAEA Symposium on International Safeguards was organized by the IAEA in cooperation with the Institute of Nuclear Materials Management and the European Safeguards Research and Development Association. It was attended by over 350 specialists and policy makers in the field of nuclear safeguards and verification from more than 50 countries and organizations. The purpose of the Symposium was to foster a broad exchange of information on concepts and technologies related to important developments in the areas of international safeguards and security. For the first time in the history of the symposia, the IAEA is issuing proceedings free of charge to participants on CD-ROM. The twenty-two plenary, technical, and poster sessions featured topics related to technological and policy aspects from national, regional and global perspectives. The theme of the Symposium: Four Decades of Development - Safeguarding into the New Millennium set the stage for the commemoration of a number of significant events in the annals of safeguards. 1997 marked the Fortieth Anniversary of the IAEA, the Thirtieth Anniversary of the Tlatelolco Treaty, and the Twentieth Anniversary of the Department of Safeguards Member State Support Programmes. There were special events and noted presentations featuring these anniversaries and giving the participants an informative retrospective view of safeguards development over the past four decades. The proceedings of this symposium provide the international community with a comprehensive view of where nuclear safeguards and verification stood in 1997 in terms of the growing demands and expectations. The Symposium offered thoughtful perspectives on where safeguards are headed within the broader context of verification issues. As the world of international nuclear verification looks towards the next millennium, the implementation of the expanding and strengthened safeguards system presents formidable challenges

  11. Proceedings of the sixth symposium on laser spectroscopy

    International Nuclear Information System (INIS)

    1998-11-01

    This proceedings contains articles of the 6th symposium on laser spectroscopy and this symposium is held on Nov. 3-4, 1998 by KAERI. Laser spectroscopy is one of the most important areas in optical science and engineering and we discussed about the recently developed subjects in detail during the this symposium. This proceedings is composed of two major parts. One is the invitational lectures and the other is the research papers. This have a very important and very valuable lecture by Dr. William Phillips who is the 1997 Nobel Laureate in Physics. His special lecture was very wonderful and fruitful. And we have a number of invited speakers from several advanced countries. Their talks are the highlights of this symposium. (Cho, G. S.)

  12. 6th European symposium on uroradiology

    International Nuclear Information System (INIS)

    Bujlov, V.M.

    1999-01-01

    Materials of the 6th European symposium on uroradiology held in Strasbourg (France) in September, 1998. Symposium topics included problems of radiological diagnosis of kidneys, renovascular hypertension, man and woman sterility, pelvis organs of men and women, functional studies of lower urinary tract, pediatric and interventional uroradiology. Great attention is paid to magnetic resonance tomography, ultrasonography and conventional biomedical radiography [ru

  13. 7th International Symposium on Gaseous Dielectrics

    CERN Document Server

    James, David

    1994-01-01

    The Seventh International Symposium on Gaseous Dielectrics was held in Knoxville, Tennessee, U. S. A. , on April 24-28, 1994. The symposium continued the interdisciplinary character and comprehensive approach of the preceding six symposia. Gaseous DielecIries VII is a detailed record of the symposium proceedings. It covers recent advances and developments in a wide range of basic, applied and industrial areas of gaseous dielectrics. It is hoped that Gaseous DielecIries VII will aid future research and development in, and encourage wider industrial use of, gaseous dielectrics. The Organizing Committee of the Seventh International Symposium on Gaseous Dielectrics consisted of G. Addis (U. S. A. ), L. G. Christophorou (U. S. A. ), F. Y. Chu (Canada), A. H. Cookson (U. S. A. ), O. Farish (U. K. ), I. Gallimberti (Italy) , A. Garscadden (U. S. A. ), D. R. James (U. S. A. ), E. Marode (France), T. Nitta (Japan), W. Pfeiffer (Germany), Y. Qiu (China), I. Sauers (U. S. A. ), R. J. Van Brunt (U. S. A. ), and W. Zaengl...

  14. NATO Symposium on Human Detection and Diagnosis of System Failures

    CERN Document Server

    Rouse, William

    1981-01-01

    This book includes all of the papers presented at the NATO Symposium on Human Detection and Diagnosis of System Failures held at Roskilde, Denmark on August 4-8, 1980. The Symposium was sponsored by the Scientific Affairs Division of NATO and the Rise National Laboratory of Denmark. The goal of the Symposium was to continue the tradition initiated by the NATO Symposium on Monitoring Behavior and Supervisory Control held in Berchtesgaden, F .R. Germany in 1976 and the NATO Symposium on Theory and Measurement of Mental Workload held in Mati, Greece in 1977. To this end, a group of 85 psychologists and engineers coming from industry, government, and academia convened to discuss, and to generate a "state-of-the-art" consensus of the problems and solutions associated with the human IS ability to cope with the increasing scale of consequences of failures within complex technical systems. The Introduction of this volume reviews their findings. The Symposium was organized to include brief formal presentations of pape...

  15. Persuasive Writing and the Student-Run Symposium

    Science.gov (United States)

    Mayer, James C.

    2007-01-01

    High school teacher James C. Mayer explains how a student-run symposium can promote "risk-taking and participation" and help students practice effective persuasion skills before demonstrating them in writing. The symposium places students in roles that encourage responsibility and ownership for discussion and learning, shifting the classroom…

  16. Low Dose Radiation-Induced Genome and Epigenome Instability Symposium and Epigenetic Mechanisms, DNA Repair, and Chromatin Symposium at the EMS 2008 Annual Meeting - October 2008

    Energy Technology Data Exchange (ETDEWEB)

    Morgan, William F; Kovalchuk, Olga; Dolinoy, Dana C; Dubrova, Yuri E; Coleman, Matthew A; Schär, Primo; Pogribny, Igor; Hendzel, Michael

    2010-02-19

    The Low Dose Radiation Symposium thoughtfully addressed ionizing radiation non-mutational but transmissable alterations in surviving cells. Deregulation of epigenetic processes has been strongly implicated in carcinogenesis, and there is increasing realization that a significant fraction of non-targeted and adaptive mechanisms in response to ionizing radiation are likely to be epigenetic in nature. Much remains to be learned about how chromatin and epigenetic regulators affect responses to low doses of radiation, and how low dose radiation impacts other epigenetic processes. The Epigenetic Mechanisms Symposium focused on on epigenetic mechanisms and their interplay with DNA repair and chromatin changes. Addressing the fact that the most well understood mediators of epigenetic regulation are histone modifications and DNA methylation. Low levels of radiation can lead to changes in the methylation status of certain gene promoters and the expression of DNA methyltransferases, However, epigenetic regulation can also involve changes in higher order chromosome structure.

  17. Symposium on Differential Geometry and Differential Equations

    CERN Document Server

    Berger, Marcel; Bryant, Robert

    1987-01-01

    The DD6 Symposium was, like its predecessors DD1 to DD5 both a research symposium and a summer seminar and concentrated on differential geometry. This volume contains a selection of the invited papers and some additional contributions. They cover recent advances and principal trends in current research in differential geometry.

  18. Kupffer cells ameliorate hepatic insulin resistance induced by high-fat diet rich in monounsaturated fatty acids: the evidence for the involvement of alternatively activated macrophages

    Directory of Open Access Journals (Sweden)

    Papackova Zuzana

    2012-03-01

    Full Text Available Abstract Background Resident macrophages (Kupffer cells, KCs in the liver can undergo both pro- or anti-inflammatory activation pathway and exert either beneficiary or detrimental effects on liver metabolism. Until now, their role in the metabolically dysfunctional state of steatosis remains enigmatic. Aim of our study was to characterize the role of KCs in relation to the onset of hepatic insulin resistance induced by a high-fat (HF diet rich in monounsaturated fatty acids. Methods Male Wistar rats were fed either standard (SD or high-fat (HF diet for 4 weeks. Half of the animals were subjected to the acute GdCl3 treatment 24 and 72 hrs prior to the end of the experiment in order to induce the reduction of KCs population. We determined the effect of HF diet on activation status of liver macrophages and on the changes in hepatic insulin sensitivity and triacylglycerol metabolism imposed by acute KCs depletion by GdCl3. Results We found that a HF diet rich in MUFA itself triggers an alternative but not the classical activation program in KCs. In a steatotic, but not in normal liver, a reduction of the KCs population was associated with a decrease of alternative activation and with a shift towards the expression of pro-inflammatory activation markers, with the increased autophagy, elevated lysosomal lipolysis, increased formation of DAG, PKCε activation and marked exacerbation of HF diet-induced hepatic insulin resistance. Conclusions We propose that in the presence of a high MUFA content the population of alternatively activated resident liver macrophages may mediate beneficial effects on liver insulin sensitivity and alleviate the metabolic disturbances imposed by HF diet feeding and steatosis. Our data indicate that macrophage polarization towards an alternative state might be a useful strategy for treating type 2 diabetes.

  19. 8th International symposium on transport phenomena in combustion

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    The 8th International Symposium on Transport Phenomena in Combustion will be held in San Francisco, California, U.S.A., July 16-20, 1995, under the auspices of the Pacific Center of Thermal-Fluids Engineering. The purpose of the Symposium is to provide a forum for researchers and practitioners from around the world to present new developments and discuss the state of the art and future directions and priorities in the areas of transport phenomena in combustion. The Symposium is the eighth in a series; previous venues were Honolulu 1985, Tokyo 1987, Taipei 1988, Sydney 1991, Beijing 1992, Seoul 1993 and Acapulco 1994, with emphasis on various aspects of transport phenomena. The current Symposium theme is combustion. The Symposium has assembled a balanced program with topics ranging from fundamental research to contemporary applications of combustion theory. Invited keynote lecturers will provide extensive reviews of topics of great interest in combustion. Colloquia will stress recent advances and innovations in fire spread and suppression, and in low NO{sub x} burners, furnaces, boilers, internal combustion engines, and other practical combustion systems. Finally, numerous papers will contribute to the fundamental understanding of complex processes in combustion. This document contains abstracts of papers to be presented at the Symposium.

  20. Verslag symposium : "M€€r welzijn zonder pijn"

    NARCIS (Netherlands)

    Driesse, M.; Kluivers-Poodt, M.

    2010-01-01

    Op 27 april 2010 hield men in Lelystad het symposium 'Meer welzijn zonder pijn' over het thema welzijn bij landbouwhuisdieren, georganiseerd door Wageningen UR Livestock Research in samenwerking met Boehringer Ingelheim. Hoewel het symposium primair bedoeld was voor rundvee- en varkensdierenartsen,

  1. Highlight: IDRC sponsors Caribbean symposium on impact of ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    12 mai 2015 ... An IDRC-sponsored symposium exploring the impact of the Internet on economic ... Le symposium commandité par le CRDI, qui a eu lieu à Saint Andrew, ... Une nouvelle recherche fait état d'arguments convaincants pour ...

  2. Panoramic view of the Fifth International Symposium on Stem Cell Therapy and Applied Cardiovascular Biotechnology, April 2008, Madrid (Spain).

    Science.gov (United States)

    Villa, Adolfo; Sanz, Ricardo; Fernandez, M Eugenia; Elizaga, Jaime; Ludwig, Indrig; Sanchez, Pedro L; Fernandez-Aviles, Francisco

    2009-03-01

    The Fifth International Symposium on Stem Cell Therapy and Applied Cardiovascular Biotechnology was held on April 24th-25th, 2008, at the Auditorium of the High Council of Scientific Research of Spain (CSIC) in Madrid, as a continuation of a series of yearly meetings, organized in an attempt to encourage translational research in this field and facilitate a positive interaction among experts from several countries, along with industry representatives and journalists. In addition, members of the Task Force of the European Society concerning the clinical investigation of the use of autologous adult stem cells for repair of the heart gathered and discussed an update of the previous consensus, still pending of publication. In this article, we summarize some of the main topics of discussion, the state-of-the-art and latest advances in this field, and new challenges brought up for the near future.

  3. Proceedings of the international nuclear power plant aging symposium

    International Nuclear Information System (INIS)

    Beranek, A.

    1989-03-01

    This report presents the proceedings of the International Nuclear Power Plant Aging Symposium that was held at the Hyatt Regency Hotel in Bethesda, Maryland, on August 30-31 and September 1, 1988. The Symposium was presented in cooperation with the American Nuclear Society, the American Society of Civil Engineers, the American Society of Mechanical Engineers, and the Institute of Electrical and Electronics Engineers. There were approximately 550 participants from 16 countries at the Symposium

  4. Introduction and Overview of the Symposium Anil Kumar (Indian ...

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. Introduction and Overview of the Symposium Anil Kumar (Indian Institute of Science, Bangalore). Symposium on Quantum Computing and Quantum Information. Notes:

  5. Conserving biodiversity on native rangelands: Symposium proceedings

    Science.gov (United States)

    Daniel W. Uresk; Greg L. Schenbeck; James T. O' Rourke

    1997-01-01

    These proceedings are the result of a symposium, "Conserving biodiversity on native rangelands" held on August 17, 1995 in Fort Robinson State Park, NE. The purpose of this symposium was to provide a forum to discuss how elements of rangeland biodiversity are being conserved today. We asked, "How resilient and sustainable are rangeland systems to the...

  6. IUTAM Symposium

    CERN Document Server

    Pedley, Timothy

    2003-01-01

    The IUTAM Symposium on Flow in Collapsible Tubes and Past Other Highly Compliant Boundaries was held on 26-30 March, 2001, at the University of Warwick. As this was the first scientific meeting of its kind we considered it important to mark the occasion by producing a book. Accordingly, at the end of the Symposium the Scientific Committee met to discuss the most appropriate format for the book. We wished to avoid the format of the conventional conference book consisting of a large number of short articles of varying quality. It was agreed that instead we should produce a limited number of rigorously refereed and edited articles by selected participants who would aim to sum up the state of the art in their particular research area. The outcome is the present book. Peter W. Ca rpenter, Warwick Timothy J. Pedley, Cambridge May, 2002. VB SCIENTIFIC COMMITTEE Co-Chair: P.W. Carpenter, Engineering, Warwiek, UK Co-Chair: TJ. Pedley, DAMTP, Cambridge, UK V.V. Babenko, Hydromechanics, Kiev, Ukraine R. Bannasch, Bionik...

  7. Bioinformatics Symposium of the Analytical Division of the American Chemical Society Meeting. Final Technical Report from 03/15/2000 to 03/14/2001 [sample pages of agenda, abstracts, index

    Energy Technology Data Exchange (ETDEWEB)

    Kennedy, Robert T.

    2000-03-28

    Sparked by the Human Genome Project, biological and biomedical research has become an information science. Information tools are now being generated for proteins, cell modeling, and genomics. The opportunity for analytical chemistry in this new environment is profound. New analytical techniques that can provide the information on genes, SNPs, proteins, protein modifications, cells, and cell chemistry are required. In this symposium, we brought together both informatics experts and leading analytical chemists to discuss this interface. Over 200 people attended this highly successful symposium.

  8. 78 FR 10180 - Annual Computational Science Symposium; Conference

    Science.gov (United States)

    2013-02-13

    ...] Annual Computational Science Symposium; Conference AGENCY: Food and Drug Administration, HHS. ACTION... Pharmaceutical Users Software Exchange (PhUSE), is announcing a public conference entitled ``The FDA/PhUSE Annual Computational Science Symposium.'' The purpose of the conference is to help the broader community align and...

  9. Annual symposium on Frontiers in Science

    Energy Technology Data Exchange (ETDEWEB)

    Metzger, N.; Fulton, K.R.

    1998-12-31

    This final report summarizes activities conducted for the National Academy of Sciences' Annual Symposium on Frontiers of Science with support from the US Department of Energy for the period July 1, 1993 through May 31, 1998. During the report period, five Frontiers of Science symposia were held at the Arnold and Mabel Beckman Center of the National Academies of Sciences and Engineering. For each Symposium, an organizing committee appointed by the NAS President selected and planned the eight sessions for the Symposium and identified general participants for invitation by the NAS President. These Symposia accomplished their goal of bringing together outstanding younger (age 45 or less) scientists to hear presentations in disciplines outside their own and to discuss exciting advances and opportunities in their fields in a format that encourages, and allows adequate time for, informal one-on-one discussions among participants. Of the 458 younger scientists who participated, over a quarter (124) were women. Participant lists for all symposia (1993--1997) are attached. The scientific participants were leaders in basic research from academic, industrial, and federal laboratories in such disciplines as astronomy, astrophysics, atmospheric science, biochemistry, cell biology, chemistry, computer science, earth sciences, engineering, genetics, material sciences, mathematics, microbiology, neuroscience, physics, and physiology. For each symposia, the 24 speakers and discussants on the program were urged to focus their presentations on current cutting-edge research in their field for a scientifically sophisticated but non-specialist audience, and to provide a sense of the experimental data--what is actually measured and seen in the various fields. They were also asked to address questions such as: What are the major research problems and unique tools in their field? What are the current limitations on advances as well as the frontiers? Speakers were asked to provide a

  10. 30th International Acoustical Imaging Symposium

    CERN Document Server

    Jones, Joie; Lee, Hua

    2011-01-01

    The International Symposium on Acoustical Imaging is a unique forum for advanced research, covering new technologies, developments, methods and theories in all areas of acoustics. This interdisciplinary Symposium has been taking place every two years since 1968. In the course of the years the proceedings volumes in the Acoustical Imaging Series have become a reference for cutting-edge research in the field. In 2009 the 30th International Symposium on Acoustical Imaging was held in Monterey, CA, USA, March 1-4. Offering both a broad perspective on the state-of-the-art as well as  in-depth research contributions by the specialists in the field, this Volume 30 in the Series contains an excellent collection of forty three papers presented in five major categories: Biomedical Imaging Acoustic Microscopy Non-Destructive Evaluation Systems Analysis Signal Analysis and Image Processing Audience Researchers in medical imaging and biomedical instrumentation experts.

  11. Proceedings of the second ERDA statistical symposium

    Energy Technology Data Exchange (ETDEWEB)

    Tietjen, G.; Campbell, K. (comps.)

    1977-04-01

    The Second ERDA Statistical Symposium, sponsored by the Energy Research and Development Administration, was held at Oak Ridge, Tennessee, October 25-27, 1976. This was the second annual symposium designed to promote interlaboratory communications among ERDA statisticians as well as contacts with statisticians from other institutions. The proceedings of the first symposium, held at Los Alamos in November, 1975, have been published by Batelle Pacific Northwest Laboratories (BNWL-1986). Separate abstracts were prepared for seven of the papers in this proceeding, all going in ERDA Energy Research Abstracts (ERA) and two in Energy Abstracts for Policy Analysis (EAPA). The remaining four have already been cited in ERA and can be found by referring to CONF-761023-- in the report number index. (RWR)

  12. NIFS symposium: toward the research of fusion burning plasmas

    International Nuclear Information System (INIS)

    Itoh, Sanae

    1993-07-01

    NIFS symposium, entitled 'Toward the research of Fusion Burning Plasmas - Present status and Future Strategy' was held at NIFS on July 15th 1992. This NIFS symposium covers various topics related to burning plasma, e.g., JET DT experiment, Plan for DT experiment on TFTR as well as the future trends among researchers. To study the critical issues and trends of future research, a questionnaire was sent to about 100 researchers. This report presents such activities in the NIFS symposium. (author)

  13. Proceedings of the 2012 symposium on nuclear data

    International Nuclear Information System (INIS)

    Nakajima, Ken; Hori, Jun-ichi

    2013-10-01

    The 2012 symposium on nuclear data organized by the Nuclear Data Division of Atomic Energy Society of Japan (AESJ) and Research Reactor Institute, Kyoto University (KURRI) was held at Kumatori, KURRI on Nov. 15th and 16th, 2012 in cooperation with Nuclear Science and Engineering Directorate of Japan Atomic Energy Agency. The symposium was devoted for presentations and discussions on the four topics: 'Nuclear Power after Fukushima Nuclear Plant Accident', 'Application of Nuclear Data', 'How Should We Deal with Covariances of Nuclear Data?' and 'Validation of JENDL-4.0 and Future', as well as poster sessions on various research fields. Tutorials on neutron resonance capture and transmission analysis, international trend of nuclear data research were also given in the symposium. Talks as well as posters presented at the symposium aroused lively discussions among approximately 83 participants. This report consists of total 35 papers including 13 oral presentations and 22 poster presentations. (author)

  14. 3rd International Symposium on Innovative Management, Information and Production

    CERN Document Server

    Xu, Bing; Wu, Berlin

    2014-01-01

    Innovative Management in Information and Production is based on the proceedings of the Third International Symposium on Innovative Managemet, Information and Production. This symposium is held by International Society of Management Engineers. The symposium took place on October 8-10, in Ho Chi Minh City, Vietnam. This book examines recent innovative management of information and productions such as digital collection management and operations planning, scheduling and control.

  15. The 2002 Starting Artificial Intelligence Researchers Symposium

    OpenAIRE

    Vidal, Thierry

    2003-01-01

    During the 2002 European Conference on Artificial Intelligence (ECAI-02) was introduced the Starting Artificial Intelligence Researchers Symposium STAIRS), the first-ever international symposium specifically aimed at Ph.D. students in AI. The outcome was a thorough, high-quality, and successful event, with all the features one usually finds in the best international conferences: large international committees, comprehensive coverage, published proceedings, renowned speakers and panelists, sub...

  16. Welcome and introduction to symposium - Day 2

    OpenAIRE

    humanities, Symposium on Information and technology in the arts and; McLaughlin, Jeremy Lee; Matusiak, Krystyna

    2015-01-01

    Welcome and introduction slides used for presentation at Day 2 of the Virtual Symposium on Information and Technology in the Arts and Humanities, held April 22 and 23, 2015. The Symposium was co-sponsored by the ASIS&T (Association for Information Science and Technology) Special Interest Group for Arts and Humanities (SIG AH) and the Special Interest Group for Visualization, Images, and Sound (SIG VIS).

  17. Nagasaki symposium on Chernobyl: Update and future. Proceedings

    International Nuclear Information System (INIS)

    Nagataki, Shigenobu

    1994-01-01

    This publication contains valuable, up-to-date scientific information on the health effects of the Chernobyl accident, obtained from almost all the leading international and national organizations. The purpose of the Nagasaki symposium on Chernobyl was to present and discuss the available data from all over the world independent of psychological, social, economic, and political bias, and thus to make conclusions that would further medical science. To this end, the symposium consisted of two sessions, 'Chernobyl update' and 'Chernobyl in the future'. Along with the proceedings of these two sessions, the proceedings of the Japan-NIS Chernobyl thyroid symposium, held in December 1993 are included in this book. (orig.)

  18. The ILL millennium symposium and European user meeting

    International Nuclear Information System (INIS)

    Carlile, C.J.; Frick, B.; Radaelli, P.G.; Alba-Simionesco, C.; Chauty, A.; Niss, K.; Casas, F.; Sokolov, A.; Lequeux, F.; Montes, H.; Harrison, A.; Schurtenberger, P.; Dubbers, D.; Frank, A.; Gudel, H.U.; Wagner, R.; Vettier, C.; Gahler, R.; Protassov, K.; Geltenbort, P.; Plonka, C.; Simpson, G.; Pinston, J.A.; Genevey, J.; Urban, W.; Scherillo, A.; Orlandi, R.; Smith, A.G.; Mana, G.; Abele, H.; Van der Grinten, M.; Steuwer, A.; Klotz, S.; Hamel, G.; Strassle, C.Th.; Kervananois, N.; Koza, M.M.; Nishiyama, Y.; Langan, P.; Wada, M.; Sugiyama, J.; Chanzy, H.; Gunter, M.M.; Lerch, M.; Boysen, H.; Korte, C.; Suard, E.; Blanco, J.A.; Fernandez-Rodriguez, J.; Brown, P.J.; Stunault, A.; Katsumata, K.; Lovesey, S.W.; Iga, F.; Michimura, S.; Kremer, R.K.; Banks, M.; Capogna, L.; Enderle, M.; Gibson, B.J.; McIntyre, G.J.; Ouladdiaf, B.; Pujol, S.; Raggazzoni, J.L.; Rheinstadter, M.; Schefer, J.; Boehm, M.; Roessli, B.; Wills, A.S.; Ouladdiaf, B.; Lelievre-Berna, E.; Goff, J.P.; Toader, A.M.; Skoulatos, M.; Enderle, M.; Stewart, J.R.; Murani, A.; Roger, M.; Shannon, N.; Kaul, E.E.; Geibel, C.; Simonet, V.; Lhotel, E.; Paulsen, C.; Ressouche, E.; Staub, U.; Amato, A.; Baines, C.; Petrakovskii, G.A.; Bramwell, S.; Fukuhara, N.; Ebert, J.; Lindner, D.; Dauvergne, M.T.; Hartlein, M.; Timmins, P.; Conti, E.; Svergun, D.; Budayova-Spano, M.; Bonnete, F.; El Hajji, M.; Blakeley, M.P.; Meilleur, F.; Castro, B.; Gabel, F.; Ferrand, M.; Chenal, A.; Forge, V.; Fragneto, G.; Haertlein, M.; Gillet, D.; Haertlein, M.

    2006-01-01

    Five years ago the ILL (Institute Laue-Langevin) convened the first Millennium symposium in order to launch an ambitious modernization program of instruments and infrastructure known as the ILL Millennium Program. After 5 years of activity we have decided to run a second such symposium. The scientific program of this Millennium Symposium will address the following points: -) instrumental and scientific achievements made possible by the Millennium Program, -) trends in science and engineering and the implications for the ILL, -) scenarios for future instrumentation and user support facilities, and -) the scientific priorities of the user community. This document gathers the abstracts of 63 contributions and 73 posters

  19. The ILL millennium symposium and European user meeting

    Energy Technology Data Exchange (ETDEWEB)

    Carlile, C.J.; Frick, B.; Radaelli, P.G.; Alba-Simionesco, C.; Chauty, A.; Niss, K.; Casas, F.; Sokolov, A.; Lequeux, F.; Montes, H.; Harrison, A.; Schurtenberger, P.; Dubbers, D.; Frank, A.; Gudel, H.U.; Wagner, R.; Vettier, C.; Gahler, R.; Protassov, K.; Geltenbort, P.; Plonka, C.; Simpson, G.; Pinston, J.A.; Genevey, J.; Urban, W.; Scherillo, A.; Orlandi, R.; Smith, A.G.; Mana, G.; Abele, H.; Van der Grinten, M.; Steuwer, A.; Klotz, S.; Hamel, G.; Strassle, C.Th.; Kervananois, N.; Koza, M.M.; Nishiyama, Y.; Langan, P.; Wada, M.; Sugiyama, J.; Chanzy, H.; Gunter, M.M.; Lerch, M.; Boysen, H.; Korte, C.; Suard, E.; Blanco, J.A.; Fernandez-Rodriguez, J.; Brown, P.J.; Stunault, A.; Katsumata, K.; Lovesey, S.W.; Iga, F.; Michimura, S.; Kremer, R.K.; Banks, M.; Capogna, L.; Enderle, M.; Gibson, B.J.; McIntyre, G.J.; Ouladdiaf, B.; Pujol, S.; Raggazzoni, J.L.; Rheinstadter, M.; Schefer, J.; Boehm, M.; Roessli, B.; Wills, A.S.; Ouladdiaf, B.; Lelievre-Berna, E.; Goff, J.P.; Toader, A.M.; Skoulatos, M.; Enderle, M.; Stewart, J.R.; Murani, A.; Roger, M.; Shannon, N.; Kaul, E.E.; Geibel, C.; Simonet, V.; Lhotel, E.; Paulsen, C.; Ressouche, E.; Staub, U.; Amato, A.; Baines, C.; Petrakovskii, G.A.; Bramwell, S.; Fukuhara, N.; Ebert, J.; Lindner, D.; Dauvergne, M.T.; Hartlein, M.; Timmins, P.; Conti, E.; Svergun, D.; Budayova-Spano, M.; Bonnete, F.; El Hajji, M.; Blakeley, M.P.; Meilleur, F.; Castro, B.; Gabel, F.; Ferrand, M.; Chenal, A.; Forge, V.; Fragneto, G.; Haertlein, M.; Gillet, D.; Haertlein, M

    2006-07-01

    Five years ago the ILL (Institute Laue-Langevin) convened the first Millennium symposium in order to launch an ambitious modernization program of instruments and infrastructure known as the ILL Millennium Program. After 5 years of activity we have decided to run a second such symposium. The scientific program of this Millennium Symposium will address the following points: -) instrumental and scientific achievements made possible by the Millennium Program, -) trends in science and engineering and the implications for the ILL, -) scenarios for future instrumentation and user support facilities, and -) the scientific priorities of the user community. This document gathers the abstracts of 63 contributions and 73 posters.

  20. Etanercept blocks inflammatory responses orchestrated by TNF-α to promote transplanted cell engraftment and proliferation in rat liver

    Science.gov (United States)

    Viswanathan, Preeti; Kapoor, Sorabh; Kumaran, Vinay; Joseph, Brigid; Gupta, Sanjeev

    2014-01-01

    Engraftment of transplanted cells is critical for liver-directed cell therapy but most transplanted cells are rapidly cleared from liver sinusoids by proinflammatory cytokines/chemokines/receptors after activation of neutrophils or Kupffer cells. To define whether TNF-α served roles in cell-transplantation-induced hepatic inflammation, we used TNF-α antagonist, etanercept, for studies in syngeneic rat hepatocyte transplantation systems. After cell transplantation, multiple cytokines/chemokines/receptors were overexpressed, whereas etanercept prior to cell transplantation essentially normalized these responses. Moreover, ETN downregulated cell transplantation-induced intrahepatic release of secretory cytokines, such as high mobility group box 1. These effects of etanercept decreased cell transplantation-induced activation of neutrophils but not of Kupffer cells. Transplanted cell engraftment improved by several-fold in etanercept-treated animals. These gains in cell engraftment were repeatedly realized after pretreatment of animals with etanercept before multiple cell transplantation sessions. Transplanted cell numbers did not change over time indicating absence of cell proliferation after etanercept alone. By contrast, in animals preconditioned with retrorsine and partial hepatectomy, cell transplantation after etanercept pretreatment significantly accelerated liver repopulation compared with control rats. We concluded that TNF-α played a major role in orchestrating cell transplantation-induced inflammation through regulation of multiple cytokines/chemokines/receptor expression. As TNF-α antagonism by etanercept decreased transplanted cell clearance, improved cell engraftment and accelerated liver repopulation, this pharmacological approach to control hepatic inflammation will help optimize clinical strategies for liver cell therapy. PMID:24844924

  1. 9th International Symposium on Lactic Acid Bacteria

    NARCIS (Netherlands)

    Kuipers, Oscar P.; Poolman, Berend; Hugenholtz, Jeroen

    What’s new in the field of lactic acid bacteria? The 9th International Symposium on Lactic Acid Bacteria (LAB9) will take place 31 August to 4 September 2008 in Egmond aan Zee, The Netherlands. Traditionally, the triannual LAB symposium focuses on the themes of genetics, physiology, and applications

  2. Proceedings of the DAE-BRNS fifth interdisciplinary symposium on materials chemistry

    International Nuclear Information System (INIS)

    Jafar, Mohsin; Tyagi, Adish; Tyagi, Deepak

    2014-12-01

    The focus of the present symposium on materials chemistry was on research areas in materials chemistry like: nuclear materials; high purity materials; nanomaterials and clusters; carbon based materials; fuel cell materials and other electro-ceramics; biomaterials; polymers and soft condensed matter; materials for energy conversion; thin films and surface chemistry; magnetic materials; catalysis; chemical sensors; organic and organometallic compounds; computational material chemistry etc. Papers relevant to INIS are indexed separately

  3. 28th International Acoustical Imaging Symposium

    CERN Document Server

    André, Michael P; Andre, Michael; Arnold, Walter; Bamber, Jeff; Burov, Valentin; Chubachi, Noriyoshi; Erikson, Kenneth; Ermert, Helmut; Fink, Mathias; Gan, Woon S; Granz, Bernd; Greenleaf, James; Hu, Jiankai; Jones, Joie P; Khuri-Yakub, Pierre; Laugier, Pascal; Lee, Hua; Lees, Sidney; Levin, Vadim M; Maev, Roman; Masotti, Leonardo; Nowicki, Andrzej; O’Brien, William; Prasad, Manika; Rafter, Patrick; Rouseff, Daniel; Thijssen, Johan; Tittmann, Bernard; Tortoli, Piero; Steen, Anton; Waag, Robert; Wells, Peter; Acoustical Imaging

    2007-01-01

    The International Acoustical Imaging Symposium has been held continuously since 1968 as a unique forum for advanced research, promoting the sharing of technology, developments, methods and theory among all areas of acoustics. The interdisciplinary nature of the Symposium and the wide international participation are two of its main strengths. Scientists from around the world present their papers in an informal environment conducive to lively discussion and cross-fertilization. The fact that a loyal community of scientists has supported this Series since 1968 is evidence of its impact on the field. The Symposium Series continues to thrive in a busy calendar of scientific meetings without the infrastructure of a professional society. It does so because those who attend and those who rely on the Proceedings as a well-known reference work acknowledge its value. This Volume 28 of the Proceedings likewise contains an excellent collection of papers presented in six major categories, offering both a broad perspective ...

  4. Rapporteurs report of the symposium

    International Nuclear Information System (INIS)

    Myerscough, Dan

    2014-01-01

    The objective of the symposium was to share current practice, experiences and innovations within the management of contaminated metallic radioactive material. The symposium was a forum for: Learning about current practices, Highlight strategic issues related to metals recycling, Exchange of experiences, Discussion of innovative and new techniques and needs for improvements, Developing and maintenance of networks in the area of metals recycling. The aim was to bring together operators, regulators, decision makers, scientists, consultants, contractors and other stakeholders. A short introduction by representatives from Studsvik, IAEA and OECD/NEA started the symposium followed by presentations by invited speakers from international organisations. Seven topical sessions covered issues relating to: 1 - Regulations and recommendations: - International recommendations and national legislation, - Application of regulations, - Regulator views; 2 - Minimising waste amounts: - Experience in minimising the generation of waste in the form of radioactive or potentially radioactive metals, - Activities to minimise the waste volumes for disposal; 3 - Characterisation and categorisation of metals to be recycled; 4 - Decontamination of metals for clearance; 5 - Melting of metals for clearance, reuse or volume reduction; 6 - Best practice in management of metals for clearance and recycling; 7 - Sustainability and public acceptance. Each session contained three to five presentations and group discussions. Each session was concluded with a short analysis of the presentations and the outcome of the group discussions. Conclusions of each session and outcome of the group discussions were presented on a Summing up the third day. The symposium also held a poster session with topics as above. This report provides a short summary of the various presentations and discussions concentrating on the key messages and outcomes of the sessions

  5. Proceedings of DAE-BRNS national symposium on Limnology

    International Nuclear Information System (INIS)

    Venkataramani, B.; Puranik, V.D.; Apte, S.K.; Gour, H.N.; Sharma, S.K.; Sharma, L.L.; Sharma, B.K.; Gupta, H.C.L.; Verma, P.C.

    2007-01-01

    The present symposium NSL addresses both the basic and applied aspects of limnology. The outcome of the symposium will help in the formulation of water policy that will result in the sustained availability of healthy fresh water resources and also benefit the industrial end user. Papers relevant to INIS are indexed separately

  6. International RILEM Symposium

    CERN Document Server

    Birgisson, Björn; Frost, David; Wang, Linbing

    2013-01-01

    The micro- and nano-modification of infrastructure materials and the associated multi-scale characterization and simulation has the potential to open up whole new uses and classes of materials, with wide-ranging implications for society. The use of multi-scale characterization and simulation brings the ability to target changes at the very small scale that predictably effect the bulk behavior of the material and thus allowing for the optimization of material behavior and performance.   The International RILEM Symposium on Multi-Scale Modeling and Characterization of Infrastructure Materials (Stockholm, June 10-12, 2013) brought together key researchers from around the world to present their findings and ongoing research in this field in a focused environment with extended discussion times. From asphalt to concrete, from chemistry to mechanics, from nano- to macro-scale: the collection of topics covered by the Symposium represents the width and depth of the currently ongoing efforts of developing more sustain...

  7. International symposium on the history of mining and metallurgy. Internationales Symposium zur Geschichte des Bergbaus und Huettenwesens

    Energy Technology Data Exchange (ETDEWEB)

    Waechtler, E; Engewald, G R [eds.

    1980-01-01

    The VII. International Symposium took place in Freiberg and Reinsberg, in the German Democratic Republic, from September 4-8, 1978. The Symposium was organized by the Executive Committee of the International Committee on the History of Technology (ICOHTEC) and was attended by 77 participants from 14 countries in Eastern and Western Europe as well as USA and Canada. A total of 51 papers were published and 30 talks were held and analyzed in discussions. The papers dealt with selected topics on the history of the mining and metallurgical industries, primarily from the fifteenth century to the twentieth century. The topics concern the development of science, of new mining and metallurgical equipment and processes, innovation in mines, increase in productivity, improvement in working conditions, economic progress and economic crisis, social aspects of the labor force and trade union movements in major mining countries. An excursion to a brown coal surface mine was organized in conjunction with the Symposium. (In German)

  8. Mining and Reclamation Technology Symposium

    Energy Technology Data Exchange (ETDEWEB)

    None Available

    1999-06-24

    The Mining and Reclamation Technology Symposium was commissioned by the Mountaintop Removal Mining/Valley Fill Environmental Impact Statement (EIS) Interagency Steering Committee as an educational forum for the members of the regulatory community who will participate in the development of the EIS. The Steering Committee sought a balanced audience to ensure the input to the regulatory community reflected the range of perspectives on this complicated and emotional issue. The focus of this symposium is on mining and reclamation technology alternatives, which is one of eleven topics scheduled for review to support development of the EIS. Others include hydrologic, environmental, ecological, and socio-economic issues.

  9. Proceedings of the 3rd NINS symposium on engineering and technology

    International Nuclear Information System (INIS)

    2008-10-01

    The 3rd NINS Symposium on Engineering and Technology was held on 24-25, July 2008 at National Institute for Fusion Science (NIFS), organized by Department of Engineering and Technical Services, NIFS. This Symposium is continuation of an annual series. The 1st one was held on 25-26 July, 2006 organized by National Astronomical Observatory of Japan. The 2nd one was held on 25-26 June, 2007 organized by Institute for Molecular Science. This proceedings is a compilation of papers presented at the symposium. 49 participants from 5 institutes of NINS attended this symposium and 23 papers were presented. (author)

  10. Effects of methyl palmitate on cytokine release, liver injury and survival in mice with sepsis.

    Science.gov (United States)

    Villa, P; Demitri, M T; Meazza, C; Sironi, M; Gnocchi, P; Ghezzi, P

    1996-12-01

    The effects of methyl palmitate (MP), a known inhibitor of Kupffer cells, were studied in a model of polymicrobial sepsis induced in CD-1 mice by cecal ligation and puncture (CLP). The inhibition of Kupffer cells by pretreatment with MP was shown by the reduced phagocytosis, the production of tumor necrosis factor (TNF) and interleukin-6 (IL-6) after lipopolysaccharide (LPS) challenge. The reduced activation of Kupffer cells resulted in lower levels of inflammatory products after CLP. TNF and IL-6 were significantly reduced in serum 2 h and 24 h respectively after CLP, interleukin-1 beta (IL-1 beta) was reduced in liver 4 h after CLP, nitric oxide (NO) and serum amyloid A (SAA) were significantly reduced 8 and 24 h respectively after CLP. Liver toxicity was significantly reduced in MP-treated mice and survival was significantly prolonged at all intervals, reaching 45% after six to ten days compared with 3% in control mice. These findings suggest that Kupffer cells play an important role in liver damage and survival in sepsis.

  11. International Symposium for the Promotion of APEC Environmental Technology Exchange; APEC kankyo gijutsu koryu sokushin symposium

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-11-11

    The International Symposium for the Promotion of APEC Environmental Technology Exchange was held under the theme `The function and role expected of the APEC Virtual Center,` with the objectives of clarifying the need for future intra-regional environmental technological exchange, defining the types of information and personnel exchange, and promoting the use of interactive character of the APEC Virtual Center for Environmental Technology Exchange by encouraging access to and participation in the Virtual Center project. It was held in the period of 11th and 12th, November in 1996, at the venue of Rinku International Convention Center in Osaka. The symposium was attended by 477 persons from nine countries, i.e., Australia, Canada, China, Indonesia, Korea, Philippines, Thailand, the US, and Japan, comprising staff members of intra-regional environment-related organizations. After the keynote speech, `Current status and tasks of environmental technology exchange`, and `Expected roles of the Virtual Center for Environmental Technology Exchange` were discussed. During the plenary session, the chairman summarized the symposium. This summary was carried on the Virtual Center homepage of the Internet

  12. 77 FR 4568 - Annual Computational Science Symposium; Public Conference

    Science.gov (United States)

    2012-01-30

    ...] Annual Computational Science Symposium; Public Conference AGENCY: Food and Drug Administration, HHS... with the Pharmaceutical Users Software Exchange (PhUSE), is announcing a public conference entitled ``The FDA/PhUSE Annual Computational Science Symposium.'' The purpose of the conference is to help the...

  13. International Ocean Symposium (IOS) 1996; Kokusai kaiyo symposium 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-02-18

    This is a proceedings of the International Ocean Symposium 1996. On the first day of the symposium, the following were given with a theme `The Ocean, Can She Save Us`: Underwater research and future of mankind as a commemorative speech; The ocean, can she save us -- trying to discover the true figure of the ocean as a keynote speech. Panel discussion was held on The global environment and the infinite potential of the ocean. On the second day, an approach was made mostly from a cultural aspect with a theme `The Ocean and the Japanese.` The following were given: Human links between east and west as a commemorative speech; The ocean and Japanese culture as a keynote speech; Civilization spanning across oceans as a panel discussion. The Japanese have been developing their individual technologies in shipbuilding, shipping, and ocean development, have been raised by Mother Ocean, and have lived together. Ocean has been supplying humans food, water, oxygen, marine routes, and even dream and hope. The environmental pollution is the result of the human greediness. It is fear and friendship between humans and ocean that can save humans and ocean.

  14. 28th International Symposium on Shock Waves

    CERN Document Server

    2012-01-01

    The University of Manchester hosted the 28th International Symposium on Shock Waves between 17 and 22 July 2011. The International Symposium on Shock Waves first took place in 1957 in Boston and has since become an internationally acclaimed series of meetings for the wider Shock Wave Community. The ISSW28 focused on the following areas: Blast Waves, Chemically Reacting Flows, Dense Gases and Rarefied Flows, Detonation and Combustion, Diagnostics, Facilities, Flow Visualisation, Hypersonic Flow, Ignition, Impact and Compaction, Multiphase Flow, Nozzle Flow, Numerical Methods, Propulsion, Richtmyer-Meshkov, Shockwave Boundary Layer Interaction, Shock Propagation and Reflection, Shock Vortex Interaction, Shockwave Phenomena and Applications, as well as Medical and Biological Applications. The two Volumes contain the papers presented at the symposium and serve as a reference for the participants of the ISSW 28 and individuals interested in these fields.

  15. XXth symposium neuroradiologicum 2014

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2014-09-15

    The volume includes abstracts from lectures and poster presentations during the XXth symposium neuroradiologicum 2014 covering the following issues: Stroke, head and neck, pediatric diagnostic neuroradiology, spine and interventional neuroradiology, adult diagnostic neuroradiology, intravascular interventional neuroradiology.

  16. Proceedings of the sixteenth biennial low-rank fuels symposium

    International Nuclear Information System (INIS)

    1991-01-01

    Low-rank coals represent a major energy resource for the world. The Low-Rank Fuels Symposium, building on the traditions established by the Lignite Symposium, focuses on the key opportunities for this resource. This conference offers a forum for leaders from industry, government, and academia to gather to share current information on the opportunities represented by low-rank coals. In the United States and throughout the world, the utility industry is the primary user of low-rank coals. As such, current experiences and future opportunities for new technologies in this industry were the primary focuses of the symposium

  17. Proceedings of the first internet symposium on nuclear data

    International Nuclear Information System (INIS)

    Fukahori, Tokio; Iwamoto, Osamu; Nakagawa, Tsuneo

    1997-03-01

    The First Internet Symposium on Nuclear Data (ISND-1) was held on the WWW home page of Nuclear Data Center at Tokai Research Establishment, Japan Atomic Energy Research Institute (JAERI), from April 8 to June 15, 1996. This symposium was organized by Japanese Nuclear Data Committee and Nuclear Data Center, JAERI and was the first trial to use 'Internet' for the symposium in a nuclear data field. In ISND-1, presented were 25 papers on various topics of nuclear data. Those presented papers are compiled in this proceedings as well as brief description about management of ISND-1. (author)

  18. Proceedings of the first internet symposium on nuclear data

    Energy Technology Data Exchange (ETDEWEB)

    Fukahori, Tokio; Iwamoto, Osamu; Nakagawa, Tsuneo [eds.] [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1997-03-01

    The First Internet Symposium on Nuclear Data (ISND-1) was held on the WWW home page of Nuclear Data Center at Tokai Research Establishment, Japan Atomic Energy Research Institute (JAERI), from April 8 to June 15, 1996. This symposium was organized by Japanese Nuclear Data Committee and Nuclear Data Center, JAERI and was the first trial to use `Internet` for the symposium in a nuclear data field. In ISND-1, presented were 25 papers on various topics of nuclear data. Those presented papers are compiled in this proceedings as well as brief description about management of ISND-1. (author)

  19. Proceedings of the 3rd Symposium on Engineering Sciences

    International Nuclear Information System (INIS)

    Ahmed, J.; Rizvi, S.Z.H.; Ahmad, R.; Saleem, M.

    2010-01-01

    The 3rd symposium on engineering sciences was held from March 10-12, 2010 in Lahore, Pakistan. More than twenty academic institutions and six industries participated in this conference. The foreign and Pakistani experts delivered their keynotes talk, contributor lectures and poster presentation on the conference topics. In three days of the symposium, Fifty four papers presented on different topics of Engineering Sciences including chemical engineering, energy engineering, metallurgy engineering, material engineering and electrical engineering. This symposium provided an ideal opportunity for exchange of information amongst scientists, engineers and researchers from all over Pakistan and other countries of the world. (A.B)

  20. Proceedings of the sixteenth biennial low-rank fuels symposium

    Energy Technology Data Exchange (ETDEWEB)

    1991-01-01

    Low-rank coals represent a major energy resource for the world. The Low-Rank Fuels Symposium, building on the traditions established by the Lignite Symposium, focuses on the key opportunities for this resource. This conference offers a forum for leaders from industry, government, and academia to gather to share current information on the opportunities represented by low-rank coals. In the United States and throughout the world, the utility industry is the primary user of low-rank coals. As such, current experiences and future opportunities for new technologies in this industry were the primary focuses of the symposium.

  1. PREFACE: XXXV Symposium on Nuclear Physics

    Science.gov (United States)

    Padilla-Rodal, E.; Bijker, R.

    2012-09-01

    Conference logo The XXXV Symposium on Nuclear Physics was held at Hotel Hacienda Cocoyoc, Morelos, Mexico from January 3-6 2012. Conceived in 1978 as a small meeting, over the years and thanks to the efforts of various organizing committees, the symposium has become a well known international conference on nuclear physics. To the best of our knowledge, the Mexican Symposium on Nuclear Physics represents the conference series with longest tradition in Latin America and one of the longest-running annual nuclear physics conferences in the world. The Symposium brings together leading scientists from all around the world, working in the fields of nuclear structure, nuclear reactions, physics with radioactive ion beams, hadronic physics, nuclear astrophysics, neutron physics and relativistic heavy-ion physics. Its main goal is to provide a relaxed environment where the exchange of ideas, discussion of new results and consolidation of scientific collaboration are encouraged. To celebrate the 35th edition of the symposium 53 colleagues attended from diverse countries including: Argentina, Australia, Canada, Japan, Saudi Arabia and USA. We were happy to have the active participation of Eli F Aguilera, Eduardo Andrade, Octavio Castaños, Alfonso Mondragón, Stuart Pittel and Andrés Sandoval who also participated in the first edition of the Symposium back in 1978. We were joined by old friends of Cocoyoc (Stuart Pittel, Osvaldo Civitarese, Piet Van Isacker, Jerry Draayer and Alfredo Galindo-Uribarri) as well as several first time visitors that we hope will come back to this scientific meeting in the forthcoming years. The scientific program consisted of 33 invited talks, proposed by the international advisory committee, which nicely covered the topics of the Symposium giving a balanced perspective between the experimental and the theoretical work that is currently underway in each line of research. Fifteen posters complemented the scientific sessions giving the opportunity

  2. Proceedings of the international symposium on materials testing reactors

    International Nuclear Information System (INIS)

    Ishihara, Masahiro; Kawamura, Hiroshi

    2009-01-01

    This report is the Proceedings of the International Symposium on Materials Testing Reactors hosted by Japan Atomic Energy Agency (JAEA). The symposium was held on July 16 to 17, 2008, at the Oarai Research and Development Center of JAEA. This symposium was also held for the 40th anniversary ceremony of Japan Materials Testing Reactor (JMTR) from achieving its first criticality. The objective of the symposium is to exchange the information on current status, future plan and so on among each testing reactors for the purpose of mutual understanding. There were 138 participants from Argentina, Belgium, France, Indonesia, Kazakhstan, Korea, the Russian Federation, Sweden, the United State, Vietnam and Japan. The symposium was divided into four technical sessions and three topical sessions. Technical sessions addressed the general topics of 'status and future plan of materials testing reactors', 'material development for research and testing reactors', irradiation technology (including PIE technology)' and 'utilization with materials testing reactors', and 21 presentations were made. Also the topical sessions addressed 'establishment of strategic partnership', 'management on re-operation work at reactor trouble' and 'basic technology for neutron irradiation tests in MTRs', and panel discussion was made. The 21 of the presented papers are indexed individually. (J.P.N.)

  3. Reaching the hip-hop generation: Final (symposium proceedings) report

    Energy Technology Data Exchange (ETDEWEB)

    1993-05-01

    The goal of this final (closing) report is to capture the flavor of the symposium held March 1 and 2, 1993 in New York City convened by Motivational Educational Entertainment, Inc. (MEE), a black-owned communications research, consulting, and video production company based in Philadelphia, Pennsylvania. The mission of MEE is to understand, reach, and positively affect inner-city youth. Traditional communication approaches from mainstream sources to at-risk youth often don`t account for the unique way youth communicate among themselves and how they relate to the media. This understanding, however, is crucial. To understand youth communication, the people who create and send both entertaining and educational messages to urban youth must be brought into the dialogue. The meeting in New York was intended to provide an important opportunity for senders to meet and evaluate the appropriateness and effectiveness of their messages. In addition, the MEE symposium provided a forum for the continuing public debate about what needs to be done to reach today`s urban teens. Included in this document is a description of symposium goals/objectives, symposium activities, the reaction to and analysis of the symposium, recommendations for future MEE courses of action, and an appendix containing copies of press articles.

  4. 1st Jagiellonian Symposium on Fundamental and Applied Subatomic Physics

    CERN Document Server

    2016-01-01

    Following the success of two meetings "II Symposium on applied nuclear physics and innovative technologies" and "II Symposium on Positron Emission Tomography" organized in 2014, this event will start a new series of conferences which will bring together scientists from the physics, nuclear medicine and healthcare. One of the main purposes of the symposium is to exchange experience and and expertise gained by various institutions in the field of applied and fundamental nuclear as well as particle physics, medical imaging, radiotherapy and healthcare.

  5. Effects of defibrotide, a novel oligodeoxyribonucleotide, on ischaemia and reperfusion injury of the rat liver.

    Science.gov (United States)

    Kim, Kwang Joon; Shin, Yong Kyoo; Song, Jin Ho; Oh, Byung Kwon; Choi, Myung Sup; Sohn, Uy Dong

    2002-02-01

    1. The purpose of this study was to investigate the protective effects of defibrotide, a single-stranded polydeoxyribonucleotide, on ischaemia-reperfusion injury to the liver using a rat model. 2. Ischaemia of the left and median lobes was created by total inflow occlusion for 30 min followed by 60 min of reperfusion. Hepatic injury was assessed by the release of liver enzymes (alanine transferase, ALT and lactic dehydrogenase, LDH). Hepatic oxidant stress was measured by superoxide production, lipid peroxidation and nitrite/nitrate formation. Leukocyte-endothelium interaction and Kupffer cell mobilization were quantified by measuring hepatic myeloperoxidase (MPO), polymorphonuclear leukocyte adherence to superior mesenteric artery (SMA) and immunostaining of Kupffer cell. 3. Defibrotide treatment resulted in a significant inhibition of postreperfusion superoxide generation, lipid peroxidation, serum ALT activity, serum LDH activity, MPO activity, serum nitrite/nitrate level, leukocyte adherence to SMA, and Kupffer cell mobilization, indicating a significant attenuation of hepatic dysfunction. 4. A significant correlation existed between liver ischaemia/reperfusion and hepatic injury, suggesting that liver ischaemia/reperfusion injury is mediated predominantly by generation of oxygen free radicals and mobilization of Kupffer cells. 5. We conclude that defibrotide significantly protects the liver against liver ischaemia/reperfusion injury by interfering with Kupffer cell mobilization and formation of oxygen free radicals. This study provides strong evidence that defibrotide has important beneficial effects on acute inflammatory tissue injury such as that occurring in the reperfusion of the ischaemic liver.

  6. Highlights from the HIV Cure and Reservoir Symposium, 11-12 September 2017, Ghent, Belgium.

    Science.gov (United States)

    Kint, Sam; Van Hecke, Clarissa; Cole, Basiel; Vandekerckhove, Linos; Sips, Magdalena

    2018-01-01

    For the second time, the HIV Cure Research Center (HCRC) at Ghent University organised the HIV Cure and Reservoir Symposium, in Ghent, Belgium, where in this two-day conference, virologists, molecular biologists, immunologists and clinicians presented the most recent achievements in the field of HIV cure, including data on therapeutic vaccines, HIV remission strategies such as 'shock and kill' or 'block and lock', benefits of early ART and potential of haematopoietic stem cell transplant in achieving cure. Furthermore, methods to characterise and quantify the HIV reservoir were discussed along with HIV reservoir characterisation in different body parts, including the central nervous system. An HIV activist and representative of a patients' agency also presented the patients' perspective on HIV cure. This report is a summary of all topics discussed during this symposium.

  7. INTRODUCTION: Physics of Low-dimensional Systems: Nobel Symposium 73

    Science.gov (United States)

    Lundqvist, Stig

    1989-01-01

    The physics of low-dimensional systems has developed in a remarkable way over the last decade and has accelerated over the last few years, in particular because of the discovery of the new high temperature superconductors. The new developments started more than fifteen years ago with the discovery of the unexpected quasi-one-dimensional character of the TTF-TCNQ. Since then the field of conducting quasi-one-dimensional organic systems have been rapidly growing. Parallel to the experimental work there has been an important theoretical development of great conceptual importance, such as charge density waves, soliton-like excitations, fractional charges, new symmetry properties etc. A new field of fundamental importance was the discovery of the Quantum Hall Effect in 1980. This field is still expanding with new experimental and theoretical discoveries. In 1986, then, came the totally unexpected discovery of high temperature superconductivity which started an explosive development. The three areas just mentioned formed the main themes of the Symposium. They do not in any way exhaust the progress in low-dimensional physics. We should mention the recent important development with both two-dimensional and one-dimensional and even zero-dimensional structures (quantum dots). The physics of mesoscopic systems is another important area where the low dimensionality is a key feature. Because of the small format of this Symposium we could unfortunately not cover these areas. A Nobel Symposium provides an excellent opportunity to bring together a group of prominent scientists for a stimulating exchange of new ideas and results. The Nobel Symposia are very small meetings by invitation only and the number of key international participants is typically in the range 25-40. These Symposia are arranged through a special Nobel Symposium Committee after proposal from individuals. This Symposium was sponsored by the Nobel Foundation through its Nobel Symposium Fund with grants from The

  8. Nuclear science symposium, 26th and symposium on nuclear power systems, 11th, 1979

    International Nuclear Information System (INIS)

    Kerns, C.R.

    1980-01-01

    Proceedings include 163 of the papers presented at the combined meetings, as well as two papers delivered at the plenary session on plant control beyond the 1980's and ionizing radiation dose hazards. One-hundred-and-sixty-two papers are indexed separately. Nuclear Science symposium included calorimeters and specific ionization (17 papers); PWC and Drift Chambers (7 papers); photo/optical detectors (10 papers); semiconductor detectors (11 papers); nuclear circuits and systems (11 papers); space instrumentation (9 papers); medical instrumentation (30 papers); data preprocessing (6 papers); data acquisition (11 papers); environmental instrumentation (15 papers); reactor instrumentation (16 papers). Fifteen Nuclear Systems Symposium papers covered: safety, RFI effects, detectors, monitoring systems, reactor protection, multiplexing of circuits, standard application, emergency planning and preparedness and operator/instrumentation interactions

  9. International Symposium for Thyroid Eye Disease (June 2016, London

    Directory of Open Access Journals (Sweden)

    Natalia Y. Sviridenko

    2017-03-01

    Full Text Available In June 2016, an International Symposium dedicated to the cutting edge research and achievements in Thyroid Eye Disease (TED diagnosis and treatment was held in London. The symposium was organized by the International Thyroid Eye Disease (ITEDs. It was attended EUGOGO, North American Neuro-Ophthalmological Society (NANOS and Orbit Society members. The symposium was attended by leading experts in the field of ophthalmology, orbital surgery and endocrinology: Rebecca S. Bahn, Maarten Mourits, Claudio Marcocci, George Kahaly, Mario Salvi, Antony Weetman, Anja Eckstein, Daniel Rootman, Geoffrey Rose, Robert Goldberg and Susanne Pitz, as well as doctors, specializing in the field of endocrinology, ophthalmology, radiology and other specialties. The symposium program was focused on the discussion of TED pathogenesis, classification and new therapeutic and surgical approaches. TED problems discussed by more than 300 professionals (65% ophthalmologists, 18% ophthalmic surgeons and 17% endocrinologists. North America was represented by 50 delegates. Representation of other continents was not less impressive.

  10. 9th International Frumkin symposium: Electrochemical technologies and materials for 21st century. Abstracts

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    Abstracts of the 9th International Frumkin symposium: Electrochemical technologies and materials for 21st century are presented. The symposium was held 24-29 October 2010 in Moscow. The symposium included the following microsymposiums: Electrical double layer and electrochemical kinetics (from phenomenological to molecular level); New processes, materials and devices for successful electrochemical transformation of energy; Corrosion and protection of materials; General and local corrosion; Electroactive composition materials; Bioelectrochemistry. The Frumkin symposium includes plenary lectures, oral and poster presentations. Official language of the symposium is English

  11. 9th International Frumkin symposium: Electrochemical technologies and materials for 21st century. Abstracts

    International Nuclear Information System (INIS)

    2010-01-01

    Abstracts of the 9th International Frumkin symposium: Electrochemical technologies and materials for 21st century are presented. The symposium was held 24-29 October 2010 in Moscow. The symposium included the following microsymposiums: Electrical double layer and electrochemical kinetics (from phenomenological to molecular level); New processes, materials and devices for successful electrochemical transformation of energy; Corrosion and protection of materials; General and local corrosion; Electroactive composition materials; Bioelectrochemistry. The Frumkin symposium includes plenary lectures, oral and poster presentations. Official language of the symposium is English [ru

  12. Memorial Symposium for Victor Weisskopf

    CERN Multimedia

    2002-01-01

    Victor 'Viki' Weisskopf, former Director General of CERN from 1961 to 1965, passed away five months ago. At that time, the Bulletin dedicated its coverpage to this brilliant physicist (19-20/2002). Now, CERN has organised a Memorial Symposium for next Tuesday 17 September, where you are cordially invited. This tribute will include the following speechs: L. Maiani: Welcome J. D. Jackson: Highlights from the career and scientific works of Victor F. Weisskopf M. Hine and K. Johnsen: Working with Viki at CERN M. Jacob: Knowledge and Wonder A member of Viki's family: Reminiscences. The Memorial Symposium will take place in the Main Auditorium at 15h. Drinks will be served in Pas Perdus at 17h 30.

  13. Proceedings of the 2011 symposium on nuclear data

    International Nuclear Information System (INIS)

    Harada, Hideo; Yokoyama, Kenji; Iwamoto, Nobuyuki; Nakamura, Shoji

    2012-12-01

    The 2011 data symposium on nuclear data, organized by the Nuclear Data Division of Atomic Energy Society of Japan (AESJ) was held at Ricotti, Tokai, on Nov. 16 and 17, 2011 in cooperation with Nuclear Science and Engineering Directorate of JAEA and North-Kanto Branch of AESJ. The symposium was devoted for discussions and presentations of current topics in the field of nuclear data such as nuclear accident and accident analysis code, innovative methods on nuclear data theory and measurements, and nuclear data applications, including 2 tutorial talks, NJOY99 and PHITS. Talks as well as posters presented at the symposium aroused lively discussions among 97 participants. This report contains 34 papers submitted from the oral and poster presenters. (author)

  14. Symposium overview: alterations in cytokine receptors by xenobiotics.

    Science.gov (United States)

    Cohen, M D; Schook, L B; Oppenheim, J J; Freed, B M; Rodgers, K E

    1999-04-01

    A symposium entitled Alterations in Cytokine Receptors by Xenobiotics was held at the 37th Annual Meeting of the Society of Toxicology (SOT) in Seattle, Washington. The symposium was sponsored by the Immunotoxicology Specialty Section of SOT and was designed to present information on the effect of several different classes of xenobiotics on various aspects of receptor function (i.e., post-receptor signal transduction of receptor expression), or the involvement of cytokine receptors in the action of the toxicant under consideration. This symposium brought together scientists in the area of receptor immunobiology whose expertise in receptor modulation encompassed those major signaling agents involved in the normal immune response, i.e., proinflammatory cytokines, chemokines, interleukins, and interferons. The following is a summary of each of the individual presentations.

  15. Symposium 2 of JENAM

    CERN Document Server

    Pasquali, Anna; Environment and the Formation of Galaxies : 30 years later

    2011-01-01

    The publication of the morphology - density relation by Alan Dressler in 1980 brought into the limelight the role played by environment in the formation and evolution of galaxies. The symposium Environment and the Formation of Galaxies: 30 years later, was organised with the purpose of establishing the environmental impact on the evolution of galaxies and its dependence on look-back time. Special emphasis was placed on the physical mechanisms that are responsible for transforming galaxies once they are accreted by a group or a cluster, including the observable imprint left in the galaxy HI distribution. Other major topics of the symposium were the environmental dependence of galaxy properties at z ≥ 1 and the implementation of environmental effects in cosmological models of galaxy formation and evolution. This book presents the edited proceedings of this stimulating meeting.

  16. Proceedings of the 13th international symposium on laser-aided plasma diagnostics

    International Nuclear Information System (INIS)

    Kawahata, Kazuo

    2007-09-01

    The 9th international symposium on LASER-AIDED PLASMA DIAGNOSTICS was held from 18th November to 21st September, 2007 at Takayama, Japan. This symposium was organized by the National Institute for Fusion Science, Toki, Japan. The topics of the symposium include laser diagnostics and diagnostics aided by lasers for fusion plasmas, industrial process plasmas, environmental plasmas as well as for other plasma applications and processes related to plasmas. Hardware development related to laser-aided plasma diagnostics is another topic. Over 80 participants attended this international symposium. 1 Akazaki lecture, 10 general talks, 10 topical talks, 12 short oral talks and 45 posters were presented. This issue is the collection of the papers presented at the title symposium. The 41 of the presented papers are indexed individually. (J.P.N.)

  17. 22nd DAE High Energy Physics Symposium

    CERN Document Server

    2018-01-01

    These proceedings gather invited and contributed talks presented at the XXII DAE-BRNS High Energy Physics (HEP) Symposium, which was held at the University of Delhi, India, on 12–16 December 2016. The contributions cover a variety of topics in particle physics, astroparticle physics, cosmology and related areas from both experimental and theoretical perspectives, namely (1) Neutrino Physics, (2) Standard Model Physics (including Electroweak, Flavour Physics), (3) Beyond Standard Model Physics, (4) Heavy Ion Physics & QCD (Quantum Chromodynamics), (5) Particle Astrophysics & Cosmology, (6) Future Experiments and Detector Development, (7) Formal Theory, and (8) Societal Applications: Medical Physics, Imaging, etc. The DAE-BRNS High Energy Physics Symposium, widely considered to be one of the leading symposiums in the field of Elementary Particle Physics, is held every other year in India and supported by the Board of Research in Nuclear Sciences (BRNS), Department of Atomic Energy (DAE), India. As man...

  18. The Third International Symposium on Space Terahertz Technology: Symposium proceedings

    Science.gov (United States)

    1992-01-01

    Papers from the symposium are presented that are relevant to the generation, detection, and use of the terahertz spectral region for space astronomy and remote sensing of the Earth's upper atmosphere. The program included thirteen sessions covering a wide variety of topics including solid-state oscillators, power-combining techniques, mixers, harmonic multipliers, antennas and antenna arrays, submillimeter receivers, and measurement techniques.

  19. Quality assurance and demolition: 2006 symposium

    International Nuclear Information System (INIS)

    Thierfeldt, S.

    2006-01-01

    The '2006 Symposium: Quality Assurance and Demolition' jointly organized by compra GmbH and Brenk Systemplanung GmbH this year again focused on quality assurance and the demolition of nuclear facilities as its main topics. The papers presented ranged from issues of clearance and disposal to demolition technologies and status reports about specific demolition projects. The sixteen presentations at the '2006 Symposium: Quality Assurance and Demolition' offered an interesting and very topical cross section of decommissioning and demolition of nuclear facilities in Germany. In 2007, the conference about similar main topics will again be held at the Schloss Bensberg Grand Hotel. (orig.)

  20. Fourth symposium on macrocyclic compounds

    International Nuclear Information System (INIS)

    Christensen, J.J.; Izatt, R.M.

    1980-01-01

    Both theoretical and experimental aspects of the properties and behavior of synthetic and naturally occurring macrocyclic compounds are covered in this symposium. This document contains abstracts of the papers

  1. Comparative gut physiology symposium: The microbe-gut-brain axis

    Science.gov (United States)

    The Comparative Gut Physiology Symposium titled “The Microbe-Gut-Brain Axis” was held at the Joint Annual Meeting of the American Society of Animal Science and the American Dairy Science Association on Thursday, July 21, 2016, in Salt Lake City Utah. The goal of the symposium was to present basic r...

  2. Proceedings of the 2010 symposium on nuclear data

    International Nuclear Information System (INIS)

    Watanabe, Yukinobu; Koura, Hiroyuki; Chiba, Satoshi

    2011-09-01

    The 2010 symposium on nuclear data organized by the Nuclear Data Division of Atomic Energy Society of Japan (AESJ) was held at C-CUBE, Chikushi Campus, Kyushu University, on November 25 and 26, 2010, with approximately 60 domestic and foreign participants, in cooperation with Advanced Science Research Center of JAEA and under financial support from the Kyushu Branch of AESJ. The symposium was devoted to presentations and discussions about recent research results in a wide variety of fields associated with nuclear data, such as JENDL-4 related evaluation and benchmark tests, nuclear data measurements and facilities, theoretical model calculations, applications, and so on. A tutorial on nuclear data evaluation for actinide nuclides was given in the symposium. This report consists of total 40 papers including 15 oral presentations and 25 poster presentations. (author)

  3. ACS Symposium on Molecular Tribology

    National Research Council Canada - National Science Library

    Gellman, Andrew

    2002-01-01

    .... The aspects of tribology covered by the symposium were quite broad but included a number of areas of importance to Air Force technologies including vapor phase lubrication, lubrication of MEMS...

  4. 6th International Symposium on Thermal Expansion

    CERN Document Server

    1978-01-01

    This 6th International Symposium on Thermal Expansion, the first outside the USA, was held on August 29-31, 1977 at the Gull Harbour Resort on Hecla Island, Manitoba, Canada. Symposium Chairman was Ian D. Peggs, Atomic Energy of Canada Limited, and our continuing sponsor was CINDAS/Purdue University. We made considerable efforts to broaden the base this year to include more users of expansion data but with little success. We were successful, however, in establishing a session on liquids, an area which is receiving more attention as a logical extension to the high-speed thermophysical property measurements on materials at temperatures close to their melting points. The Symposium had good international representation but the overall attendance was, disappointingly, relatively low. Neverthe­ less, this enhanced the informal atmosphere throughout the meeting with a resultant frank exchange of information and ideas which all attendees appreciated. A totally new item this year was the presentation of a bursary to ...

  5. 6. Kassel symposium on energy system engineering. On-site energy generation using renewable energy sources. Proceedings 2001; 6. Kasseler Symposium: Energie-Systemtechnik. Erneuerbare Energien und rationelle Energieverwendung. Innovative Energiewandler. Tagungsband 2001

    Energy Technology Data Exchange (ETDEWEB)

    Caselitz, P. (comp.)

    2001-07-01

    The sixth Kassel symposium on energy system engineering. On-site energy generation using renewable energy sources focuses on the subject of innovative energy converter. The status and the development of generally known technologies is not only supposed to be reported on but also some conversion methods, which are currently not too well known. The changed frame conditions in the field of energy economy cause some systems, which have already been developed, to appear in a new light. The first talk of this symposium does not really discuss a method of energy conversion compared to the other talks. It rather describes a scenario that focuses on silicium as future energy carrier. Further contributions report on new, innovative concepts for electrical partial systems of wind and water power plants with variable revolution. Modern design methods for water turbines are presented with the example of hydraulic turbo-engines. Three contributions present the current status of technology and perspectives in the field of photovoltaics, thermal photovoltaics as well as new developments in the field of solarthermal systems. Talks about micro gas turbines and fuel cells discuss the use of these systems in dual purpose power plants and in the field of energy supply for houses. Information about modern steam engines and the use of Stirling engines in the field of biomass utilization complete the subject range of this symposium. (orig.) [German] Das 6. Kasseler Symposium zur Nutzung erneuerbarer Energien und rationellen Energieverwendung widmet sich dem Thema Innovative Energiewandler. Dabei soll nicht nur ueber den Stand und die Entwicklung weithin bekannter Technologien berichtet werden. Vorgestellt werden auch einige Konversionsverfahren, deren Bekanntheitsgrad heute noch gering ist. Auch lassen die veraenderten Rahmenbedingungen in der Energiewirtschaft einige im Prinzip entwickelte Systeme moeglicherweise in einem neuen Licht erscheinen. Der erste Beitrag des Symposiums setzt

  6. Organizational Change. Symposium 11. [Concurrent Symposium Session at AHRD Annual Conference, 2000.

    Science.gov (United States)

    2000

    This packet contains three papers from a symposium on organizational change. The first paper, "Kaizen Blitz: Rapid Learning to Facilitate Immediate Organizational Improvements" (Robert B. Gudgel, Fred C. Feitler), describes rapid and dramatic improvement in the organizational performance of a manufacturing firm after use of a series of…

  7. Proceedings of the 1st JAERI symposium on HTGR technologies

    International Nuclear Information System (INIS)

    1990-07-01

    This report was edited as the Proceedings of the 1st JAERI Symposium on HTGR Technologies, - Design, Licensing Requirements and Supporting Technologies -, collecting the 21 papers presented in the Symposium. The 19 of the presented papers are indexed individually. (J.P.N.)

  8. SYMPOSIUM ON REMOTE SENSING IN THE POLAR REGIONS

    Science.gov (United States)

    The Arctic Institute of North America long has been interested in encouraging full and specific attention to applications of remote sensing to polar...research problems. The major purpose of the symposium was to acquaint scientists and technicians concerned with remote sensing with some of the...special problems of the polar areas and, in turn, to acquaint polar scientists with the potential of the use of remote sensing . The Symposium therefore was

  9. Proceedings of the symposium on technology in laboratories

    International Nuclear Information System (INIS)

    1988-10-01

    The Symposium on Technology in Laboratories was held on March 29 and 30, 1988 at Toyota Auditorium in Nagoya University. This symposium was hosted by Institute of Plasma Physics. Participants were about 210 and 54 papers were presented from many of Japanese universities and laboratories. Technical experience and new technics were reported and discussed divided into five sessions; technologies of manufacture, cryogenic, diagonostic and control system, computer and experimental apparatus. (author)

  10. Report on the First International Symposium Science in Judo (ISSJ

    Directory of Open Access Journals (Sweden)

    Félix Mateo-Cubo

    2017-12-01

    Full Text Available This report resumes the First International Symposium Science in Judo (ISSJ, organized by the Department of Health Psychology, Miguel Hernández University, Elche (Spain, and held from October 12 to 14h, 2017. During this symposium some of the most relevant research projects related to judo as a sport were presented. There were a wide variety of topics, including biomechanics of technique, health, psychology, nutrition, sport training, education and future prospects. Five plenary sessions, six mini-sessions, one panel discussion and two workshops on tatami were developed. The symposium was an event where important national and international researchers participated. It was intended for groups related to judo, such as Sports Sciences students, judo coaches and high level judo athletes. More than 70 people participated in the symposium whose main aim was to provide scientific evidence on judo to judo professionals.

  11. Proceedings of the symposium on nitride fuel cycle technology

    International Nuclear Information System (INIS)

    2004-12-01

    This report is the Proceedings of the Symposium of Nitride Fuel Cycle Technology, which was held on July 28, 2004, at the Tokai Research Establishment of the Japan Atomic Energy Research Institute. The purpose of this symposium is to exchange information and views on nitride fuel cycle technology among researchers from foreign and domestic organizations, and to discuss the recent and future research activities. The topics in the symposium are Present State of the Technology Development in the World and Japan, Fabrication Technology, Property Measurement and Pyrochemical Process. The intensive discussion was made among 53 participants. This report consists of 2 papers as invited presentations and 12 papers as contributed papers. (author)

  12. Third Symposium on Macrocyclic Compounds

    International Nuclear Information System (INIS)

    1979-01-01

    At the Third Symposium on Macrocyclic Compounds there were sessions on facilitated transport, analytical applications, organic synthesis and reactions, phase transfer catalysis, and metal complexation. Abstracts of the individual presentations are included

  13. First Ladies' Symposium on Early Childhood in Egypt (Cairo, Egypt, May 21, 2001).

    Science.gov (United States)

    O'Gara, Chloe

    This document is comprised of the papers presented at the First Ladies' Symposium on Early Childhood in Egypt in May 2001. Participating in the symposium were representatives from the World Bank, the Amsterdam Institute for International Development, the Children's Project, and the Academy for Educational Development. The symposium opened with an…

  14. Sanibel Symposium in the Petascale-Exascale Computational Era

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, Hai-Ping [Univ. of Florida, Gainesville, FL (United States)

    2016-12-23

    The 56th Sanibel Symposium was held February 14-19 2016 at the King and Prince Hotel, St. Simons Island, GA. It successfully brought quantum chemists and chemical and condensed matter physicists together in presentations, posters, and informal discussions bridging those two communities. The Symposium has had a significant role in preparing generations of quantum theorists. As computational potency and algorithmic sophistication have grown, the Symposium has evolved to emphasize more heavily computationally oriented method development in chemistry and materials physics, including nanoscience, complex molecular phenomena, and even bio-molecular methods and problems. Given this context, the 56th Sanibel meeting systematically and deliberately had sessions focused on exascale computation. A selection of outstanding theoretical problems that need serious attention was included. Five invited sessions, two contributed sessions (hot topics), and a poster session were organized with the exascale theme. This was a historic milestone in the evolution of the Symposia. Just as years ago linear algebra, perturbation theory, density matrices, and band-structure methods dominated early Sanibel Symposia, the exascale sessions of the 56thmeeting contributed a transformative influence to add structure and strength to the computational physical science community in an unprecedented way. A copy of the full program of the 56th Symposium is attached. The exascale sessions were Linear Scaling, Non-Adabatic Dynamics, Interpretive Theory and Models, Computation, Software, and Algorithms, and Quantum Monte Carlo. The Symposium Proceedings will be published in Molecular Physics (2017). Note that the Sanibel proceedings from 2015 and 2014 were published as Molecular Physics vol. 114, issue 3-4 (2016) and vol. 113, issue 3-4 (2015) respectively.

  15. Anti-inflammatory liposomes have no impact on liver regeneration in rats

    DEFF Research Database (Denmark)

    Jepsen, Betina Norman; Andersen, Kasper Jarlhelt; Knudsen, Anders Riegels

    2015-01-01

    Introduction: Surgical resection is the gold standard in treatment of hepatic malignancies, giving the patient the best chance to be cured. The liver has a unique capacity to regenerate. However, an inflammatory response occurs during resection, in part mediated by Kupffer cells, that influences...... the speed of regeneration. The aim of this study was to investigate the effect of a Kupffer cell targeted anti-inflammatory treatment on liver regeneration in rats. Methods: Two sets of animals, each including four groups of eight rats, were included. Paired groups from each set received treatment......-6. Conclusion: Low dose dexamethasone targeted to Kupffer cells does not affect histological liver cell regeneration after 70% hepatectomy in rats, but reduces the inflammatory response judged by circulating markers of inflammation. (C) 2015 The Authors. Published by Elsevier Ltd on behalf of IJS...

  16. Transport arrangements for the scientific symposium

    CERN Multimedia

    2000-01-01

    Parking in the region of building 180 will be severely restricted during the LEPFest scientific symposium of 10-11 October, and a special bus service will operate to ferry people to and from the event. From 8:00 am, buses will leave the reception at building 33, stop to pickup passengers outside the hostels (buildings 38 and 39), and drop people off at the symposium venue - building 180. At the end of each day’s proceedings, the buses will bring people back, and through out the day a shuttle service will operate around every 15-20 minutes. Attendees are strongly recommended to use the buses.

  17. 11th AG STAB/DGLR Symposium

    CERN Document Server

    Heinemann, Hans-Joachim; Hilbig, Reinhard

    1999-01-01

    This volume contains the papers of the 11th Symposium of the AG STAB (German Aerospace Aerodynamics Association). In this association those scientists and engineers from universities, research-establishments and industry are involved, who are doing research and project work in numerical and experimental fluid mechanics and aerodynamics for aerospace and other applications. Many of the contributions are giving results from the "Luftfahrtforschungsprogramm der Bundesregierung (German Aeronautical Research Programme). Some of the papers report on work sponsored by the Deutsche Forschungsgemeinschaft, DFG, which also was presented at the symposium. The volume gives a broad overview over the ongoing work in this field in Germany.

  18. The 13th Tihany Symposium on Radiation Chemistry

    Science.gov (United States)

    Wojnárovits, László; Takács, Erzsébet

    2016-07-01

    The Symposium was held in Balatonalmádi, a beautiful city by the Lake Balaton, Hungary, between August 29 and September 3, 2015. This time - to meet the expectations of many colleagues and friends - a place close to the village Tihany was selected, where the first Tihany Symposium was organized in 1962. The participants beside the excellent lectures could also enjoy the panorama of the Lake from the rooms and from the terrace of Hotel Ramada. The number of participants was close to 170 from about 33 countries. The highest number of participants arrived from Poland (14), followed by France (11), Turkey (9) and China (9). The Symposium had 6-6 colleagues from Brazil, Israel, and Romania. Beside China, Asia was represented by a few scientists from the Republic of Korea, Malaysia, Thailand, Philippines and from Saudi Arabia.

  19. Proceedings of the 1992 symposium on nuclear data

    Energy Technology Data Exchange (ETDEWEB)

    Baba, Mamoru [ed.; Tohoku Univ., Sendai (Japan); Nakagawa, Tsuneo [ed.; Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1993-03-15

    The 1992 Symposium on Nuclear Data was held at Tokai Research Establishment, Japan Atomic Energy Research Institute (JAERI), on 26th and 27th of November, 1992. The symposium was organized by Japanese Nuclear Data Committee and Nuclear Data Center, JAERI. The program of the symposium is listed below. In the oral session, a total of 15 papers were presented under the sessions of present status of revision work of JENDL-3, adjustment of group constants, nuclear data in medium energy region, nuclear data evaluation methods, integral data analyses and topics. In the poster session, presented were 25 papers concerning experiments, evaluations and benchmark tests of nuclear data. Activities of JNDC working groups were also displayed in the poster session. All of the 40 papers except the reports from JNDC working groups are compiled in this proceedings.

  20. Red blood cells, still vital after all these years: Commentary on Canadian Blood Services' International Symposium 2017.

    Science.gov (United States)

    Qadri, Syed M; Donkor, David A; Yan, Matthew; Ning, Shuoyan; Branch, Donald R; Seghatchian, Jerard; Sheffield, William P

    2018-04-01

    Canadian Blood Services (CBS), Canada's national blood transfusion service, has for many years sponsored an annual conference, for the education and awareness of interested participants, showcasing the latest evidence-based understanding of both basic science and clinical issues in transfusion medicine and science. The 15th iteration of this symposium took place September 9, 2017 and focused on some of the vital aspects of red blood cells (RBC), in line with the" 3Rs" concept, namely the provision of the Right red blood cell (RBC) product to the Right patient at the Right time. Presentations touched upon: the evolution of blood banking in North America; the monocyte monolayer assay as a predictor of post-transfusion hemolysis; hemoglobin-based oxygen carriers; RBC alloimmunization; serological approaches to complex RBC antibody problems; randomized clinical trials related to the age of stored RBC; RBC genotyping; pathophysiology, prevention and treatment of hemolytic disease of the fetus and newborn (HDFN); and testing and timing in perinatal serology. This commentary provides summaries of all speakers' presentations annotated with relevant references. Special thanks are due to all contributors for their praiseworthy approaches in sharing their experiences and knowledge on this interesting scientific/clinical and management theme. Copyright © 2018 Elsevier Ltd. All rights reserved.

  1. Birch symposium proceedings

    Science.gov (United States)

    W.T. Doolittle; P.E. Bruns

    1969-01-01

    This symposium on yellow and paper birch is the third in a series of meetings devoted to discussion of our fine hardwood timber species. The first meeting, held at Carbondale, Illinois, in 1966, dealt with black walnut. The second, held at Houghton, Michigan, in 1968, dealt with sugar maple. The purpose of this third meeting is to bring together our present knowledge...

  2. Proceedings of the international symposium NUCEF 2005

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-08-01

    Japan Atomic Energy Research Institute (JAERI) held the international symposium NUCEF 2005 at Techno Community Square RICOTTI in Tokai-mura on February 9 and 10, 2005. This symposium was co-organized by Japan Nuclear Cycle Development Institute (JNC), and Nuclear Fuel Cycle Safety Research Committee authorized the program. Two hundred thirty-nine participants from 11 countries presented fifty-nine papers, and discussed recent research activities and its outputs on waste disposal safety, fuel cycle facility safety including criticality safety, and separation process development. The presented papers are compiled in the proceedings. (author)

  3. Outcome of UNIDO symposium on biomass energy

    International Nuclear Information System (INIS)

    Nazemi, A.H.

    1997-01-01

    The results of the UNIDO symposium are presented. The symposium covered a variety of subjects, beginning with a comparison of biomass energy production and potential uses in different regions, specific country case studies about the present situation and trends in biomass energy utilisation. Technological aspects discussed included the production of biomass resources, their conversion into energy carriers and technology transfer to developing countries. An analysis of financial resources available and mechanisms for funding biomass projects were given. Environmental effects and some relatively successful biomass projects under development were described. (K.A.)

  4. Eleventh symposium on energy engineering sciences: Proceedings

    International Nuclear Information System (INIS)

    1993-01-01

    The Eleventh Symposium on Energy Engineering Sciences was held on May 3--5, 1993, at the Argonne National Laboratory, Argonne, Illinois. These proceedings include the program, list of participants, and the papers that were presented during the eight technical sessions held at this meeting. This symposium was organized into eight technical sessions: Surfaces and interfaces; thermophysical properties and processes; inelastic behavior; nondestructive characterization; multiphase flow and thermal processes; optical and other measurement systems; stochastic processes; and large systems and control. Individual projects were processed separately for the databases

  5. Symposium on high temperature and materials chemistry

    International Nuclear Information System (INIS)

    1989-10-01

    This volume contains the written proceedings of the Symposium on High Temperature and Materials Chemistry held in Berkeley, California on October 24--25, 1989. The Symposium was sponsored by the Materials and Chemical Sciences Division of Lawrence Berkeley Laboratory and by the College of Chemistry of the University of California at Berkeley to discuss directions, trends, and accomplishments in the field of high temperature and materials chemistry. Its purpose was to provide a snapshot of high temperature and materials chemistry and, in so doing, to define status and directions

  6. Symposium on high temperature and materials chemistry

    Energy Technology Data Exchange (ETDEWEB)

    1989-10-01

    This volume contains the written proceedings of the Symposium on High Temperature and Materials Chemistry held in Berkeley, California on October 24--25, 1989. The Symposium was sponsored by the Materials and Chemical Sciences Division of Lawrence Berkeley Laboratory and by the College of Chemistry of the University of California at Berkeley to discuss directions, trends, and accomplishments in the field of high temperature and materials chemistry. Its purpose was to provide a snapshot of high temperature and materials chemistry and, in so doing, to define status and directions.

  7. Proceedings of the First International Symposium on Robust Design 2014

    DEFF Research Database (Denmark)

    The symposium concerns the topic of robust design from a practical and industry orientated perspective. During the 2 day symposium we will share our understanding of the need of industry with respect to the control of variance, reliability issues and approaches to robust design. The target audience...

  8. Nuclear Structure: Dubna Symposium 1968. Invited Papers from the International Symposium on Nuclear Structure

    International Nuclear Information System (INIS)

    1968-01-01

    Invited papers of a Symposium organized by the Joint Institute for Nuclear Research, Dubna, supported by IUPAP and IAEA, and held in Dubna from 4 to 11 July 1968. The meeting was attended by about 450 scientists from 30 countries. The volume contains the invited papers, all by distinguished scientists, and the discussions and short contributions that followed the presentation of these papers. Contents: I. Nuclear structure at low excitations (15 papers) ; II. Nuclear structure at high excitations (6 papers): III. Open problems in nuclear physics (3 papers); IV. Equilibrium deformations (6 papers); V. General properties of nuclei (6 papers); VI. Closing remarks; List of contributions; List of seminar papers; List of participants; Author index. All papers, discussions and short contributions are in English; the abstracts are in English and Russian, which were the working languages of the Symposium. (author)

  9. International Evoked Potentials Symposium

    CERN Document Server

    1980-01-01

    The past decade has seen great progress in the measurement of evoked potentials in man; a steady increase in our understanding of their charac­ teristics, their origins and their usefulness; and a growing application in the field of clinical diagnosis. The topic is a truly multidisciplinary one. Important research contributions have been made by workers of many different backgrounds and clinical applications span the specialities. This book represents a revised and updated version of the work originally presented at the international evoked potential symposium held in Nottingham 4-6 1978. The Nottingham Symposium provided a forum for a state-of-the-art discussion amongst workers from many different disciplines and from many different countries. For each major topic in the field an expert review set the scene for discussion of current research presentations. This format is retained in the book: the chapters in Part A provide the context in which the research presented in Part B is set. The task of selecting m...

  10. Massive WDM and TDM Soliton Transmission Systems : a ROSC Symposium

    CERN Document Server

    2002-01-01

    This book summarizes the proceedings of the invited talks presented at the “International Symposium on Massive TDM and WDM Optical Soliton Tra- mission Systems” held in Kyoto during November 9–12, 1999. The symposium is the third of the series organized by Research Group for Optical Soliton C- munications (ROSC) chaired by Akira Hasegawa. The research group, ROSC, was established in Japan in April 1995 with a support of the Japanese Ministry of Post and Telecommunications to promote collaboration and information - change among communication service companies, communication industries and academic circles in the theory and application of optical solitons. The symposium attracted enthusiastic response from worldwide researchers in the field of soliton based communications and intensive discussions were made. In the symposium held in 1997, new concept of soliton transmission based on dispersion management of optical fibers were presented. This new soliton is now called the dispersion managed soliton. The p...

  11. Ninth international symposium on radiopharmacology

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    The goal of this Symposium is to provide a forum for those international scientists involved in applying the principles of pharmacology and radiation biology to the development of agents for the diagnosis and treatment of disease. The program will highlight state-of-the-art progress in the development of those agents used in conjunction with some form of radiation such as radiopharmaceuticals, radiopaques, photo- and radiosensitizing drugs, and neutron capture agents. An underlying pharmacokinetic parameter associated with all these agents is the need for site-specific delivery to an organ or tumor. Therefore, a major goal of the symposium will be to address those pharmacologic principles for targeting molecules to specific tissue sites. Accordingly, session themes will include receptor-mediated processes, membrane transporters, antibody interactions, metabolic trapping, and oligonucleotide-antisense mechanisms.

  12. Ninth international symposium on radiopharmacology

    International Nuclear Information System (INIS)

    1995-01-01

    The goal of this Symposium is to provide a forum for those international scientists involved in applying the principles of pharmacology and radiation biology to the development of agents for the diagnosis and treatment of disease. The program will highlight state-of-the-art progress in the development of those agents used in conjunction with some form of radiation such as radiopharmaceuticals, radiopaques, photo- and radiosensitizing drugs, and neutron capture agents. An underlying pharmacokinetic parameter associated with all these agents is the need for site-specific delivery to an organ or tumor. Therefore, a major goal of the symposium will be to address those pharmacologic principles for targeting molecules to specific tissue sites. Accordingly, session themes will include receptor-mediated processes, membrane transporters, antibody interactions, metabolic trapping, and oligonucleotide-antisense mechanisms

  13. 1979 international symposium on lepton and photon interactions at high energies

    Energy Technology Data Exchange (ETDEWEB)

    Kirk, T.B.W.; Abarbanel, H.D.I.

    1979-01-01

    This symposium on Leptons and Photons is ninth in the series of biannual meetings which began at Cambridge, Massachusetts, in 1963. Abstracts of individual items from the symposium were prepared separately for the data base. (GHT)

  14. International symposium on NMR spectroscopy

    International Nuclear Information System (INIS)

    The publication consists of 32 papers and presentations from the field of NMR spectroscopy applications submitted to the International Symposium on NMR Spectroscopy held at Smolenice between 29 Sep and 3 Oct, 1980. (B.S.)

  15. Proceedings of the 5th underground coal conversion symposium

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-05-01

    The 5th underground coal conversion symposium was held at Alexandria, Virginia, June 18--21, 1979. Thirty-three papers have been entered individually into EDB and ERA. Seven papers were also abstracted for Energy Abstracts for Policy Analysis. Seven papers had been entered previously from other sources. The symposium was sponsored by the US Department of Energy, Division of Fossil Fuel Extraction. (LTN)

  16. Nanomaterials for Polymer Electrolyte Membrane Fuel Cells; Materials Challenges Facing Electrical Energy Storate

    Energy Technology Data Exchange (ETDEWEB)

    Gopal Rao, MRS Web-Editor; Yury Gogotsi, Drexel University; Karen Swider-Lyons, Naval Research Laboratory

    2010-08-05

    Symposium T: Nanomaterials for Polymer Electrolyte Membrane Fuel Cells Polymer electrolyte membrane (PEM) fuel cells are under intense investigation worldwide for applications ranging from transportation to portable power. The purpose of this seminar is to focus on the nanomaterials and nanostructures inherent to polymer fuel cells. Symposium topics will range from high-activity cathode and anode catalysts, to theory and new analytical methods. Symposium U: Materials Challenges Facing Electrical Energy Storage Electricity, which can be generated in a variety of ways, offers a great potential for meeting future energy demands as a clean and efficient energy source. However, the use of electricity generated from renewable sources, such as wind or sunlight, requires efficient electrical energy storage. This symposium will cover the latest material developments for batteries, advanced capacitors, and related technologies, with a focus on new or emerging materials science challenges.

  17. Physiology and Endocrinology Symposium. Factors controlling puberty in beef heifers

    Science.gov (United States)

    The Physiology and Endocrinology Symposium on “Factors controlling puberty in beef heifers” was held at the joint annual meeting of the American Dairy Science Association and the American Society of Animal Science in New Orleans, Louisiana, USA, July 10 to 14, 2011. The objective of the symposium w...

  18. Proceedings of the 13th symposium on advanced photon research

    International Nuclear Information System (INIS)

    2013-09-01

    The 13th Symposium on Advanced Photon Research was held at Kansai Photon Science Institute, Japan Atomic Energy Agency (JAEA-KPSI) in Kizugawa-shi, Kyoto on November 15 - 16, 2012. This report consists of invited and contributed papers presented at the oral and poster sessions in the Symposium. (author)

  19. Symposium summary and prognosis

    International Nuclear Information System (INIS)

    Bjorken, J.D.

    1975-11-01

    The summary of the symposium on high energy physics experiments includes phenomena at low energies, the foundations of physics (considered to be mainly gravitation and quantum electrodynamics), standards of reference used for interpretation of experimental data, the new physics, particle proliferation, theoretical development, and a prognosis for the future

  20. Tenth annual underground coal gasification symposium: proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Burwell, E.; Docktor, L.; Martin, J.W. (eds.)

    1984-12-01

    The Tenth Annual Underground Coal Gasification Symposium was cosponsored by the Fossil Energy Division of the US Department of Energy and the Morgantown Energy Technology Center's Laramie Projects Office. The purpose of the symposium was to provide a forum for presenting research results and for determining additional research needs in underground coal gasification. This years' meeting was held in Williamsburg, Virginia, during the week of August 12 through 15, 1984. Approximately 120 attendees representing industry, academia, national laboratories, Government, and eight foreign countries participated in the exchange of ideas, results, and future research plans. International representatives included participants from Belgium, Brazil, France, the Netherlands, New Zealand, Spain, West Germany, and Yugoslavia. During the three-day symposium, sixty papers were presented and discussed in four formal presentation sessions and two informal poster sessions. The papers describe interpretation of field test data, results of environmental research, and evaluations of laboratory, modeling, and economic studies. All papers in this Proceedings have been processed for inclusion in the Energy Data Base.

  1. Collaborative Care Transitions Symposium: Insights from Participants.

    Science.gov (United States)

    Jeffs, Lianne; Saragosa, Marianne; Zahradnik, Michelle; Maione, Maria; Hindle, Aimee; Santiago, Cecilia; Krock, Murray; Stergiopoulos, Vicky; Bulmer, Beverly; Mitchell, Kaleil; McNamee, Colleen; Ramji, Noor

    2017-01-01

    There are promising signs that interprofessional collaborative practice is associated with quality care transitions and improved access to patient-centred healthcare. A one-day symposium was held to increase awareness and capacity to deliver quality collaborative care transitions to interprofessional health disciplines and service users. A mixed methods study was used that included a pre-post survey design and interviews to examine the impact of the symposium on knowledge, attitudes and practice change towards care transitions and collaborative practice with symposium participants. Our survey results revealed a statistically significant increase in only a few of the scores towards care transitions and collaborative practice among post-survey respondents. Three key themes emerged from the qualitative analysis, including: (1) engaging the patient at the heart of interprofessional collaboration and co-design of care transitions; (2) having time to reach out, share and learn from each other; and (3) reflecting, reinforcing and revising practice. Further efforts that engage inter-organizational learning by exchanging knowledge and evaluating these forums are warranted. Copyright © 2017 Longwoods Publishing.

  2. Contemporary Physics: Trieste Symposium 1968. Vol. I. Proceedings of the International Symposium on Contemporary Physics

    International Nuclear Information System (INIS)

    1969-01-01

    In June 1968, the International Centre for Theoretical Physics was privileged to hold an extended symposium on contemporary physics — an event probably unique in that its aim was to range over and review not just one specialized aspect of modern physics but its entire spectrum. The symposium brought together a group of 300 leading specialists in particle physics, theory of condensed matter, astrophysics, relativity, plasma physics, cosmology, nuclear physics, quantum electronics and biophysics; they lived together for three weeks, to deliver, to discuss and to listen to lectures in depth on their various specialities. The intention was to acquire, if possible, a deeper sense of the scope and unified nature of the general subject — physics — by sharing the insights of its fascinatingly diverse disciplines. The present two volumes are a record of the proceedings of the symposium. The first groups papers presented on condensed and plasma matter, on earth and in the universe; the second deals with theory of matter at very small distances and fundamentals of quantum theory. How far did we succeed in achieving the objectives of the symposium? Did we succeed in communicating to those in other disciplines the present situation in our own — the problems, the prospects? Did we emerge, three weeks after, as universal in our outlook and competence as the great physicists of even forty years ago, who could, with felicity, pass from one discipline to another enriching each? How much cross-fertilization was achieved? To what extent were the hierarchy of disciplines and the barriers between generations broken? In retrospect — and particularly in retrospect — the answers to these questions appear positive: we succeeded perhaps partially; but far more than anyone anticipated. There is no doubt that communication is a difficult art. There was so much ground to be covered before the treasures of one's own discipline could be unfolded. We could not easily forget those in

  3. Li-Fraumeni syndrome: Discovery and future challenges - Joseph Fraumeni Symposium

    Science.gov (United States)

    In May 2014, NCI’s Division of Cancer Epidemiology and Genetics (DCEG) hosted Cancer Epidemiology: From Pedigrees to Populations, a scientific symposium honoring 50 years of visionary leadership by Dr. Joseph F. Fraumeni, Jr., the founding Director of DCEG. In this video, Dr. Stephen Chanock of NCI provides opening remarks. Dr. David Schottenfeld of the University of Michigan moderates a session on the search for cancer susceptibility genes. Dr. Louise Strong of University of Texas MD Anderson Cancer Center speaks about the discovery and future challenges of Li-Fraumeni syndrome research. For more information on this symposium, visit http://dceg.cancer.gov/news-events/Fraumeni-symposium-speakers.

  4. 2006 Rare Neuroimmunological Disorders Symposium; Sheraton Inner Harbor, Baltimore, MD, July 20-23, 2006

    DEFF Research Database (Denmark)

    Kerr, DA; Antel, JP; Arnold, DL

    2007-01-01

    On July 20-22nd 2006, the second International Rare Neuroimmunologic Disorders Symposium was held in Baltimore, Maryland. The purpose of this symposium was to bring together diverse groups interested in immune-mediated disorders of the nervous system. The symposium was not disease-specific but at...

  5. Report on the BIAPWS 2009 symposium on power plant chemistry

    Energy Technology Data Exchange (ETDEWEB)

    Bignold, Geoff [GJB Chemistry for Power Ltd., Ashtead, Surrey, (United Kingdom)

    2009-06-15

    The British and Irish Association for the Properties of Water and Steam held a Workshop on Chemical Aspects of Flexible Operation of Plant and a Symposium on Environmental and Operational Issues on 21-22 April 2009 at Beeston, Nottingham. Summaries of the eight papers presented at the symposium are provided. (orig.)

  6. Go Tell Alcibiades: Tragedy, Comedy, and Rhetoric in Plato's "Symposium"

    Science.gov (United States)

    Crick, Nathan; Poulakos, John

    2008-01-01

    Plato's "Symposium" is a significant but neglected part of his elaborate and complex attitude toward rhetoric. Unlike the intellectual discussion of the "Gorgias" or the unscripted conversation of the "Phaedrus," the "Symposium" stages a feast celebrating and driven by the forces of "Eros." A luxuriously stylish performance rather than a rational…

  7. 3rd symposium on tires and chassis; 3. Symposium Reifen und Fahrwerk

    Energy Technology Data Exchange (ETDEWEB)

    Geringer, B.; Stumpf, H. (comps.)

    2005-07-01

    The present volume contains the talks, which were held at the 3rd symposium on ''Tires and chassis'' at the Institute for combustion machines at the Technical University Vienna on 26th September 2005 in cooperation with UAMTTC and Semperit Reifen Ges.m.H. Apart from technical improvements on chassis, tires and carriageway the overall perspective will get more important in the future, which also includes the driver, the neighbour, the environment and the traffic policy. Due to an increasing number of international participants, discussions can be expected, which will take into consideration extraordinary and manifold perspectives. The third symposium on ''Tires and chassis'' discusses the following developments, of which some are evolutionary. (a) Tire engineering; environmental aspects of tires, roll resistance of tires, driving comfort of tires, winter tires for passenger vehicles and trucks. (b) vehicle engineering, engineering of a race car chassis by means of telemetric measuring data acquisition; simulation of steering wheel vibrations on a complete vehicle test stand. (c) Vehicle steering; chassis of tracklaying vehicles; automatic air pressure control. (orig.)

  8. FIP Symposium 1997 (South Africa); FIP Symposium 1997 (Minami Africa) ni sankashite

    Energy Technology Data Exchange (ETDEWEB)

    Niwano, T. [Oriental Construction Co. Ltd., Tokyo (Japan); Shinagawa, K.; Takahashi, T.

    1997-07-31

    FIP (Federation Internationale de la Precontrainte) Symposium was held in Johannesburg, South Africa. Ikeda and others were sent by the Japan Prestressed Concrete Engineering Association to participate the symposium and visit some bridges in Hong Kong and South Africa. As the keynote addresses, the trends of PC in South Africa, Europe, America, East Asia and Australia was reported. Japanese papers among 105 presented papers are as follows: Iwasaki`s `Construction method of the railway PC skew slab bridge, Natori-Gawa bridge`, Toda`s `Construction of the suspended slab bridge longest in the world, Yume Tsuri-bashi`, Iizuka`s `Experiment on earthquake characteristics of precast concrete columns` and Sugita`s `Study on concrete using high-activity rice hull ash`. The group visited Kap Shui Mun bridge (Hong Kong) of 750m long constructed by Japanese JV which is the 5-span continuous complex cable stayed bridge, and featured by PC box girder structure of side spans. The group also visited Gouritz River PC bridge in South Africa. 5 refs., 10 figs.

  9. Proceedings of the symposium on the physics and technology of reactors

    International Nuclear Information System (INIS)

    1993-01-01

    The symposium aimed at providing the opportunity for promoting the subject and for developing the human resources in this important field in the Arab States. The symposium included 32 lectures on the following topics related to research reactors: design and development, training and operation, calculations of reactor parameters, nuclear reactions dynamics and control, reactor physics, neutron pyhsics, neutron activation analysis, in-core reactor radiation protection and shielding calculations. The lectures of the symposium were distributed over 7 sessions. An additional session was held by all participants for open discussion and recommendations

  10. Tenth international symposium on environmental biogeochemistry

    Energy Technology Data Exchange (ETDEWEB)

    Ehrlich, H.L.

    1992-01-01

    The primary task of this Symposium on Environmental Biogeochemistry was to examine our current understanding of GLOBAL CHANGE AND THE BIOGEOCHEMISTRY OF RADIATIVE TRACE GASES. The symposium was divided into 12 non-overlapping sessions: Paleoatmospheres and paleoclimates; Global distributions and atmospheric reactions; Poster presentations on the topics of sessions 1, 2, 4, 5, and 7; Terrestrial systems and land use change - 1; Terrestrial and land use change - 11; Fluxes and cycling in aquatic systems; Metals, organics, and depositional environments; Poster presentations on the topics of sessions 6, 9, 10 and 12; Biological Mechanisms of formation and destruction - 1; Biological mechanisms of formation and destruction - 11; High latitude systems; and Global sources, sinks, and feedbacks.

  11. Proceedings of the DAE-BRNS life sciences symposium on current trends in biology and medicine

    International Nuclear Information System (INIS)

    2010-01-01

    This year's Life Sciences Symposium is focused on Health Sciences. It will provide an interactive platform for deliberations on current developments in basic research on cancer, diabetes, infectious diseases, reproduction, stem cells and degenerative diseases. Several aspects like metabolism, use of biophysical techniques, detection methods, micro RNA based regulation, assisted reproductive technologies etc. are covered. Papers relevant to INIS are indexed separately

  12. European Cosmic Ray Symposium

    CERN Multimedia

    Pattison,B

    1992-01-01

    13me Symposium qui se déroule du 27 au 31 juillet pour la première fois au Cern. Brian Pattison ouvre la cérémonie et donne la parole à Dr.Ugland (qui représente le DG C.Rubbia excusé) et d'autres intervenants

  13. PREFACE: Fourth International Symposium on Atomic Technology

    Science.gov (United States)

    Okada, Shigefumi

    2010-04-01

    The International Symposium on Atomic Technology (ISAT) is held every year. The 4th Symposium (ISAT-4) was held on November 18-19, 2009 at the Seaside Hotel MAIKO VILLA KOBE, Kobe City, Japan presided by the "Atomic Technology Project". The ISAT-4 symposium was intended to offer a forum for the discussion on the latest progress in the atomic technologies. The symposium was attended by 107 delegates. There were 10 invited and 6 oral presentations. The number of poster presentations was 69. From all the contributions, 22 papers selected through review process are contained in this volume. The "Atomic Technology Project" was started in 2006 as a joint project of three institutions; (1) the Center for Atomic and Molecular Technologies, Graduate School of Engineering, Osaka University (CAMT), (2) the Tsukuba Research Center for Interdisciplinary Materials Science, Graduate School of Pure and Applied Sciences, University of Tsukuba (TIMS) and (3) the Polyscale Technology Research Center, Research Institute for Science and Technology, Tokyo University of Science (PTRC), each of which were independently pursuing nano-technologies and was developing atomic scale operation and diagnostics, functional materials, micro processing and device. The project is funded by the Ministry of Education, Culture, Sports, Science and Technology of Japan. The goal of the project is to contribute to the development of atomic-scale science and technologies such as functional molecules, biomaterials, and quantum functions of atomic-scale structures. Shigefumi Okada Conference Chair Center for Atomic and Molecular Technologies, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita-city, Osaka 565-0871, Japan. Conference photograph Kobe photograph

  14. SASP - Symposium on atomic, cluster and surface physics `94

    Energy Technology Data Exchange (ETDEWEB)

    Maerk, T D; Schrittwieser, R; Smith, D

    1994-12-31

    This international symposium (Founding Chairman: W. Lindinger, Innsbruck) is one in a continuing biennial series of conferences which seeks to promote the growth of scientific knowledge and its effective exchange among scientists in the field of atomic, molecular, cluster and surface physics and related areas. The symposium deals in particular with interactions between ions, electrons, photons, atoms, molecules, and clusters and their interactions with surfaces. (author).

  15. 10. Symposium energy and environment - responsibility for the future

    International Nuclear Information System (INIS)

    2003-01-01

    The symposium discussed important aspects relating to the subject of energy and environment. The detailed and well-funded lectures and statements were received with great interest by the 120 attendants. The discussion focused on problems of power generation and consumption, increased shares of renewable energy sources, ethical and theological questions. The symposium received funds from Deutsche Bundesstiftung Umwelt and was well accepted by the press [de

  16. Proceedings Forest & Field Fuels Symposium

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-07-01

    The purpose of the symposium is to examine two specific renewable resources, forest and field fuels, to pinpoint areas where funding of RD&D would be effective in expanding their marketability and use as substitutes for imported oil.

  17. Research symposium proceedings. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1991-12-31

    THE research symposium was organized to present the cutting edge research for PET by individuals from leading institutions throughout the world. The Institute for Clinical PET (ICP) has focused its annual meeting on the clinical applications of PET.

  18. Finding the Motivation: The Evolution of a Faculty Scholarship Symposium

    Science.gov (United States)

    Pifer, Meghan J.; Reisboard, Dana; Staulters, Mimi; Li, Xiaobao; Gozza-Cohen, Mary; McHenry, Nadine; Schaming, Susan; Gilio, Brenda

    2014-01-01

    This article describes the evolution of a faculty scholarship symposium within the school of education at a regional comprehensive university. The article outlines the initial structure and goals of the symposium as well as the development of the model over time. The influence of leadership, culture, and individual goals and backgrounds are…

  19. Functional and Logic Programming - 14th International Symposium (FLOPS 2018)

    DEFF Research Database (Denmark)

    This volume contains the proceedings of the 14th International Symposium on Functional and Logic Programming - FLOPS 2018 - held in Nagoya, Japan, May 9 - 11, 2018......This volume contains the proceedings of the 14th International Symposium on Functional and Logic Programming - FLOPS 2018 - held in Nagoya, Japan, May 9 - 11, 2018...

  20. Symposium in Honour of T.A. Springer

    CERN Document Server

    Hesselink, Wim; Kallen, Wilberd; Strooker, Jan

    1987-01-01

    From 1-4 April 1986 a Symposium on Algebraic Groups was held at the University of Utrecht, The Netherlands, in celebration of the 350th birthday of the University and the 60th of T.A. Springer. Recognized leaders in the field of algebraic groups and related areas gave lectures which covered wide and central areas of mathematics. Though the fourteen papers in this volume are mostly original research contributions, some survey articles are included. Centering on the Symposium subject, such diverse topics are covered as Discrete Subgroups of Lie Groups, Invariant Theory, D-modules, Lie Algebras, Special Functions, Group Actions on Varieties.

  1. Proceedings of the Symposium on Nuclear Energy and Environment

    International Nuclear Information System (INIS)

    1993-01-01

    The symposium was organized and set against the background of the industry is traditional concern for safety and the environment. The purpose of the symposium was to contribute further to the international bank of knowledge by describing recent experience, especially of Latin-America countries, in adopting, adapting and developing the practices of the industry for ensuring safety and compatibility with the environment. In the cause of four days, june 28 to july 1993, thirty five papers were presented, besides fourteen articles were arranged in the following sessions: invited speakers, safety and risk assessment, environmental protection, waste management and disposal emergency planning and public acceptance and health aspects. The Latin American Section of the American Nuclear Society convened the symposium in the city of Rio de Janeiro, Brazil. (B.C.A.)

  2. International Symposium on Optics and its Applications (OPTICS-2011)

    Science.gov (United States)

    Bhattacherjee, Aranya B.; Calvo, Maria L.; Kazaryan, Eduard M.; Papoyan, Aram V.; Sarkisyan, Hayk A.

    2012-03-01

    OPTICS Logo PREFACE The papers selected for this volume were reported at the International Symposium 'Optics and its applications' (OPTICS-2011, Yerevan & Ashtarak, Armenia, September 5-9, 2011), http://www.ipr.sci.am/optics2011/. The Symposium was organized by the SPIE Armenian Student Chapter and major Armenian R&D organizations, universities and industrial companies working in the field of basic and applied optics: Institute for Physical Research of the National Academy of Sciences of Armenia, Yerevan State University, Russian-Armenian (Slavonic) University, and LT-PYRKAL Closed Joint Stock Company. OPTICS-2011 was primarily intended to support and promote the involvement of students and young scientists in various fields of modern optics, giving them the possibility to attend invited talks by prominent scientists and to present and discuss their own results. Furthermore, the Symposium allowed foreign participants from 14 countries to become acquainted with the achievements of optical science and technology in Armenia, which became a full member of the International Commission for Optics (ICO) in 2011. To follow this concept, the Symposium sessions were held in various host institutions. The creative and friendly ambience established at OPTICS-2011 promoted further international collaboration in the field and motivated many students to take up research in optics and photonics as a career. This volume of Journal of Physics: Conference Series covers thematic sections of the Symposium (both oral and poster), which represent the main fields of interest in optics for Armenian scientists: quantum optics & information, laser spectroscopy, optical properties of nanostructures, photonics & fiber optics, and optics of liquid crystals. Such wide coverage is consistent with the general scope of the Symposium, allowing all the students involved in optics to present, discuss and publish their recent results, and for those who are making their first steps in science to choose

  3. VIII international electric vehicle symposium

    Energy Technology Data Exchange (ETDEWEB)

    1986-01-01

    The proceedings from the symposium are presented. Major topics discussed include: battery technology, powertrains; hybrid vehicles, marketing and economics, propulsion, and electric vehicle design and performance. Each paper has been separately indexed for inclusion in the Energy Data Base.

  4. Ethics and Integrity. Symposium 27. [Concurrent Symposium Session at AHRD Annual Conference, 2000.

    Science.gov (United States)

    2000

    This packet contains three papers on ethics and integrity from a symposium on human resource development (HRD). The first paper, "Factors Influencing Ethical Resolution Efficacy: A Model for HRD Practitioners" (Kimberly S. McDonald), proposes a model of ethical resolution efficacy for HRD practitioners. The model suggests that factors related to…

  5. Issues of HRD. Symposium.

    Science.gov (United States)

    2002

    This document contains three papers from a symposium on issues of human resource development (HRD). "The Complex Roots of Human Resource Development" (Monica Lee) discusses the roots of HRD within the framework of the following views of management: (1) classic (the view that managers must be able to create appropriate rules and…

  6. Atlantic white cedar: ecology, restoration, and management: Proceedings of the Arlington Echo symposium

    Science.gov (United States)

    Philip Sheridan

    2005-01-01

    A symposium was held on the globally threatened and coastally restricted tree species, Atlantic white-cedar (Chamaecyparis thyoides (L) B.S.P.) at the Arlington Echo Outdoor Education Center, Millersville, MD, in June 2003. The theme of the symposium was “Uniting Forces for Action,” and participants in the symposium came from throughout the range of this species, from...

  7. PREFACE: 9th National Symposium on Polymeric Materials (NSPM 2009)

    Science.gov (United States)

    Ali, Aidy; Salit, Sapuan

    2010-07-01

    NSPM 2009 is the formal proceedings of the 9th National Symposium on Polymeric Materials held in Residence Hotel Uniten Bangi on 14-16 December 2009. It is also organised with The Plastics and Rubber Institute Malaysia PRIM. The symposium proceedings consists of 94 papers covering a large number of issues on experimental and analytical studies of polymeric materials. The objectives of the symposium are to review the state-of-the art, present and latest findings and exchange ideas among engineers, researchers and practitioners involved in this field. We strongly hope the outcomes of this symposium will stimulate and enhanced the progress of experimental and analytical studies on polymeric materials as well as contribute to the fundamental understanding in related fields. After careful refereeing of all manuscripts, 15 papers were selected for publications in this issue. Another 20 papers were selected for publication in Pertanika Journal of Science and Technology (PJST). The content of the material and its rapid dissemination was considered to be more important than its form. We are grateful to all the authors for their papers and presentations in this symposium. They are also the ones who help make this symposium possible through their hard work in the preparation of the manuscripts. We would also like to offer our sincere thanks to all the invited speakers who came to share their knowledge with us. We would also like to acknowledge the untiring efforts of the reviewers, research assistants and students in meeting deadlines and for their patience and perseverance. We are indeed honoured to associate this event with Department of Mechanical and Manufacturing, and Faculty of Engineering, Universiti Putra Malaysia. Finally, we appreciate the sponsor support provided by Faculty of Engineering, The Plastics and Rubber Institute Malaysia (PRIM) and PETRONAS Malaysia. Thank you all. Editors: Aidy Ali and S M Sapuan

  8. 7th international symposium on internal combustion diagnostics. Proceedings; 7. Internationales Symposium fuer Verbrennungsdiagnostik. Beitraege

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    At one time combustion pressure indicating was the ''trigger'' for this symposium, and today it still serves as the basis for continued investigation of combustion phenomena. It now finds application throughout the development process, as more sophisticated analysis of conventional signals is possible. Understanding of localized combustion phenomena is substantially simplified by means of optical diagnostic methods, the application of which has reached a certain level of standardization. The presentations will cover specific topics including fuel spray analysis, ignition events and information about gas mixtures. The comparison and combination of results from measurement and simulation shed light on the complex processes in the combustion chamber. What's more, the linkage of two complementary methods offers substantial cost savings through reductions in test hardware and shorter development times. Focused application of all of the available tools allows us better to understand combustion processes, recognize the influential parameters and derive control algorithms. The latter are subsequently to be found in engines that fulfill both regulatory requirements and customer expectations. So it is that the symposium captures the current state of the art in combustion diagnostics through a combination of indicating, optical diagnostics and simulation, and offers both the methodology expert and the engine developer the ideal platform for discussion of today's issues - and to form their own opinions on them. Anyone wanting to keep up to date in this continuously developing and ever more complex area of activity certainly can't afford to miss our symposium. (orig.)

  9. Proceedings of the symposium on molecular biology and radiation protection

    International Nuclear Information System (INIS)

    Marko, A.M.

    1996-02-01

    The symposium on molecular biology and radiation protection was organized in sessions with the following titles: Radiation protection and the human genome; Molecular changes in DNA induced by radiation; Incidence of genetic changes - pre-existing, spontaneous and radiation-induced; Research directions and ethical implications. The ten papers in the symposium have been abstracted individually

  10. Proceedings of the symposium on molecular biology and radiation protection

    Energy Technology Data Exchange (ETDEWEB)

    Marko, A M [Atomic Energy Control Board, Ottawa, ON (Canada). Advisory Committee on Radiological Protection; Myers, D K; Atchison, R J [Atomic Energy Control Board, Ottawa, ON (Canada). Advisory Committee on Radiological Protection. Secretariat; Gentner, N E [Atomic Energy of Canada Ltd., Chalk River, ON (Canada)

    1996-02-01

    The symposium on molecular biology and radiation protection was organized in sessions with the following titles: Radiation protection and the human genome; Molecular changes in DNA induced by radiation; Incidence of genetic changes - pre-existing, spontaneous and radiation-induced; Research directions and ethical implications. The ten papers in the symposium have been abstracted individually.

  11. Nuclear fusion: Pursuing the Soft [Symposium on fusion technology] option

    International Nuclear Information System (INIS)

    Kenward, M.

    1991-01-01

    Fusion research has come a long way since the fusion community held the first Symposium on fusion technology (Soft) in Britain 30 years ago. Some of the recent achievements of the Jet project are reported from this year's symposium, the 16th in the series, held in London at the beginning of September. (author)

  12. Report. First international symposium on innovating mining systems

    Energy Technology Data Exchange (ETDEWEB)

    Blackwood, R L

    1985-01-01

    The author presents a summary of proceedings of the First International Symposium on Innovative Mining Systems held at Massachusetts Institute of Technology, USA 4-5 November 1985, together with some comments on the conclusions and discussion throughout. The Symposium agenda included the following (i) Symposium intentions and expectations; (ii) International; (iii) Developments in safety; (iv) Overview of current major research and trends; (v) Panel discussion: Mechanisms for industrial and international collaboration; (vi) Closing remarks; (vii) Review of innovations: university programs; (viii) Review of selected mine operator programs and needs; Review of equipment innovations; capabilities and trends in areas of mining equipment and robotics; Concurrent sessions: operations and manufacturing. A series of workshops was also held, the titles of which were as follows: (i) Establishment of research network; (ii) Entry development-machine excavation; (iii) Sensing, monitoring, diagnostics, artificial intelligence; (iv) Remote control, automation, mining systems; (v) Computer aided design, simulation, system development; (vi) Surface mining; (vii) Rock breakage.

  13. Crafoord Symposium on Magnetospheric Physics : Achievements and Prospects

    CERN Document Server

    Fälthammar, C-G

    1990-01-01

    This book contains the proceedings of the 1989 Crafoord Symposium organized by the Royal Swedish Academy of Sciences. The scientific field for the Crafoord Prize of 1989 was decided in 1988 by the Academy to be Magnetospheric Physics. On September 27,1989 the Academy awarded the 1989 Crafoord Prize to Professor J. A. Van Allen, Iowa City, USA "for his pioneer work in space research, in particular for the discovery of the high energy charged particles that are trapped in the Earth's magnetic field and form the radiation belts -often called the Van Allen belts - around the Earth". The subject for the Crafoord Symposium, which was held on September 28-29 at the Royal Swedish Academy of Sciences in Stockholm, was Magnetospheric Physics, Achievements and Prospects. Some seventy of the world's leading scientists in magnetospheric physics (see list of participants) were invited to the Symposium. The program contained only invited papers. After the ?resentation of the Crafoord Prize Laureate, Prof. J . A. Van Allen, ...

  14. 2nd International Industrial Symposium on the Supercollider

    CERN Document Server

    IISSC; Supercollider 2

    1990-01-01

    The Second International Industrialization Symposium on the Supercollider, IISSC, was held in Miami Beach Florida on March 14-16, 1990. It was an even bigger and more successful meeting than our ftrst in New Orleans in 1989. There were 691 attendees and 75 exhibitors. The enthusiasm shown by both the speakers and the audience was exhilarating for all attendees. The symposium again brought together the physicists and engineers designing the machine, the industrial organizations supporting the design and construction, the education community, and the governmental groups responsible for the funding and management of the SSC project. We believe it is this unique rnix which makes this particular meeting so valuable. The theme of this symposium was "The SSC-Americas Research Partnership" and the varied presentations throughout the meeting high-lighted that theme. The keynote speakers were: Dr. Roy Schwitters, Director of the SSC Mr. Paul F. Orefftce, Chairman of the Board of Dow Chemical Company Honorable W. Hinson...

  15. Proceedings of the High Consequence Operations Safety Symposium

    Energy Technology Data Exchange (ETDEWEB)

    1994-12-01

    Many organizations face high consequence safety situations where unwanted stimuli due to accidents, catastrophes, or inadvertent human actions can cause disasters. In order to improve interaction among such organizations and to build on each others` experience, preventive approaches, and assessment techniques, the High Consequence Operations Safety Symposium was held July 12--14, 1994 at Sandia National Laboratories, Albuquerque, New Mexico. The symposium was conceived by Dick Schwoebel, Director of the SNL Surety Assessment Center. Stan Spray, Manager of the SNL System Studies Department, planned strategy and made many of the decisions necessary to bring the concept to fruition on a short time scale. Angela Campos and about 60 people worked on the nearly limitless implementation and administrative details. The initial symposium (future symposia are planned) was structured around 21 plenary presentations in five methodology-oriented sessions, along with a welcome address, a keynote address, and a banquet address. Poster papers addressing the individual session themes were available before and after the plenary sessions and during breaks.

  16. 44th Aerospace Mechanisms Symposium

    Science.gov (United States)

    Boesiger, Edward A. (Compiler)

    2018-01-01

    The Aerospace Mechanisms Symposium (AMS) provides a unique forum for those active in the design, production and use of aerospace mechanisms. A major focus is the reporting of problems and solutions associated with the development and flight certification of new mechanisms.

  17. X Latin American Symposium on Nuclear Physics and Applications. Book of Abstracts

    International Nuclear Information System (INIS)

    2013-12-01

    The 10th Latin American Symposium on Nuclear Physics and Applications will be held on December 1-6, 2013 in Montevideo, Uruguay. The symposium will be preceded by a School on Medical Physics, on November 29-30, 2013. The symposium is organized by the Universidad de la Repùblica, Montevideo, by the National Superconducting Cyclotron Laboratory, Michigan, USA, and by the Thomas Jefferson National Accelerator Facility, Virginia, USA. This is the tenth event in a series which were previously held in Venezuela, Colombia, Mexico, Brazil, Argentina, Peru, Chile and Ecuador. Traditionally, the purpose of these symposia is the dissemination of major theoretical and experimental advances in nuclear science, with emphasis on research topics carried out by Latin American groups or in collaborations involving institutions from Latin America. The topics of the symposium include: Nuclear and Hadron Structure and Interactions Nuclear Reactions and Phases of Nuclear Matter Nuclear and Particle Astrophysics Tests of Fundamental Symmetries and Properties of Neutrinos Nuclear Applications New Facilities and Instrumentation.The 10th Latin American Symposium on Nuclear Physics and Applications will be held on December 1-6, 2013 in Montevideo, Uruguay. The symposium will be preceded by a School on Medical Physics, on November 29-30, 2013. The symposium is organized by the Universidad de la República, Montevideo, by the National Superconducting Cyclotron Laboratory, Michigan, USA, and by the Thomas Jefferson National Accelerator Facility, Virginia, USA. This is the tenth event in a series which were previously held in Venezuela, Colombia, Mexico, Brazil, Argentina, Peru, Chile and Ecuador. Traditionally, the purpose of these symposia is the dissemination of major theoretical and experimental advances in nuclear science, with emphasis on research topics carried out by Latin American groups or in collaborations involving institutions from Latin America. The topics of the symposium include

  18. 77 FR 4544 - CPSC Symposium on Phthalates Screening and Testing Methods

    Science.gov (United States)

    2012-01-30

    ... Screening and Testing Methods AGENCY: Consumer Product Safety Commission. ACTION: Notice. SUMMARY: The... symposium on phthalates screening and testing methods. The symposium will be held at the CPSC's National... submit comments, identified by Docket No. CPSC-2012-0008, by any of the following methods: Electronic...

  19. Proceedings of the 2009 annual symposium on nuclear data. NDS2009

    International Nuclear Information System (INIS)

    Koura, Hiroyuki; Chiba, Satoshi

    2010-12-01

    The annual nuclear data symposium, organized by the Nuclear Data Division of Atomic Energy Society of Japan (AESJ) was held at Ricotti, Tokai, on Nov. 26 and 27, 2009 in cooperation with Advanced Science Research Center of JAEA and under financial support from North-Kanto Branch of AESJ. The symposium was devoted for discussions and presentations of research results in wide variety of fields related to nuclear data, including 3 tutorial talks. Talks as well as posters presented at the symposium aroused lively discussions among approximately 90 participants. This report contains 17 papers submitted from the talkers and poster presenters. (author)

  20. Proceedings of the 4th international symposium on material testing reactors

    International Nuclear Information System (INIS)

    Ishihara, Masahiro; Suzuki, Masahide

    2012-03-01

    This report is the Proceedings of the fourth International Symposium on Material Testing Reactors hosted by Japan Atomic Energy Agency (JAEA). The first symposium was held on 2008, at the Oarai Research and Development Center of JAEA, the second, 2009, Idaho National Laboratory (INL) of United States and the third 2010, Nuclear Research Institute (NRI) in Czech Republic to exchange information for deep mutual understanding of material testing reactors. The fourth symposium was originally scheduled to be held INVAP in Argentina. However, the aftermath of volcanic explosion at Chili forced the symposium to change place. Total 111 participants attended from Argentina, Belgium, France, Germany, Indonesia, Malasia, Korea, South Africa, Switzerland, the United State and Japan. This symposium addressed the general topics of 'status and future plan of material testing reactors', 'advancement of irradiation technology', 'expansion of industry use(RI)', 'facility, upgrade, aging management', 'new generation MTR', 'advancement of PIE technology', 'development of advanced driver fuel', and 'nuclear human resource development(HRD) for next generation', and 39 presentations were made. Furthermore, three topics, 'Necessity of cooperation for Mo-99 production by (n,gamma) reaction', 'Necessity of standardization of irradiation technology' and 'Conceptual design of next generation materials testing reactor by collaboration', were selected and discussed. (author)

  1. Proceedings of the 4th international symposium on material testing reactors

    Energy Technology Data Exchange (ETDEWEB)

    Ishihara, Masahiro; Suzuki, Masahide [Japan Atomic Energy Agency, Oarai Research and Development Center, Oarai, Ibaraki (Japan)

    2012-03-15

    This report is the Proceedings of the fourth International Symposium on Material Testing Reactors hosted by Japan Atomic Energy Agency (JAEA). The first symposium was held on 2008, at the Oarai Research and Development Center of JAEA, the second, 2009, Idaho National Laboratory (INL) of United States and the third 2010, Nuclear Research Institute (NRI) in Czech Republic to exchange information for deep mutual understanding of material testing reactors. The fourth symposium was originally scheduled to be held INVAP in Argentina. However, the aftermath of volcanic explosion at Chili forced the symposium to change place. Total 111 participants attended from Argentina, Belgium, France, Germany, Indonesia, Malasia, Korea, South Africa, Switzerland, the United State and Japan. This symposium addressed the general topics of 'status and future plan of material testing reactors', 'advancement of irradiation technology', 'expansion of industry use(RI)', 'facility, upgrade, aging management', 'new generation MTR', 'advancement of PIE technology', 'development of advanced driver fuel', and 'nuclear human resource development(HRD) for next generation', and 39 presentations were made. Furthermore, three topics, 'Necessity of cooperation for Mo-99 production by (n,gamma) reaction', 'Necessity of standardization of irradiation technology' and 'Conceptual design of next generation materials testing reactor by collaboration', were selected and discussed. (author)

  2. Proceedings of the 10th symposium on advanced photon research

    International Nuclear Information System (INIS)

    2010-06-01

    The 10th Symposium on Advanced Photon Research was held at Kansai Photon Science Institute, Japan Atomic Energy Agency (JAEA-KPSI) in Kizugawa, Kyoto on October 21 - 22, 2009. This report consists of invited and contributed papers presented at the oral and poster sessions in the Symposium. The 38 of the presented papers are indexed individually. (J.P.N.)

  3. Proceedings of the 11th symposium on advanced photon research

    International Nuclear Information System (INIS)

    2011-03-01

    The 11th Symposium on Advanced Photon Research was held at Kansai Photon Science Institute, Japan Atomic Energy Agency (JAEA-KPSI) in Kizugawa, Kyoto on June 24 - 25, 2010. This report consists of invited and contributed papers presented at the oral and poster sessions in the Symposium. The 29 of the presented papers are indexed individually. (J.P.N.)

  4. Proceedings of the European Symposium on Pressure Equipment - ESOPE 2007

    International Nuclear Information System (INIS)

    2007-01-01

    Every three years, and since thirty years, the AFIAP organizes a symposium where the experts and actors working in the field of pressure equipments, whether fixed or transportable, can meet and exchange on all developments related to their activity. What was at first called the 'National Congress on the technology of pressure components', and later the 'Study Days on pressure components', became since 2001 the 'European Symposium on Pressure Equipment' (ESOPE), so marking an opening to the European and International fields in a context marked by the application of the European Directives applicable to these equipments. The 2001 symposium was more particularly dedicated to the application of the directives harmonizing the construction of equipments, and the 2004 symposium was more particularly centred on the management of equipments in operation. For the ESOPE 2007 Symposium, the organizing committee wished to resume these two subjects under the aspects of the safety, the competitiveness, as well as the innovation. The plenary session of the last day will be completely dedicated to these subjects and will include a Panel discussion, where National and European authorities, representatives of manufacturers and users, as well as experts engaged in developments and new projects will express their views. These exchanges will also permit to answer the questions expressed by the participants. Every symposium has thus a main orientation, but shall also be the place of exchanges on the different subjects wished by the profession. The traditional technical sessions are consequently maintained: - Sessions on Design and Materials, - Sessions on Fabrication, - Sessions on Fitness for Service, and a special session dedicated to the National, European and International Codes is added, the afternoon of the first day. The plenary Opening session is also devoted to this last subject with lectures on the evolutions of European regulations, the orientations retained for pressure

  5. Immunohistochemical characterisation of the hepatic stem cell niche in feline hepatic lipidosis: a preliminary morphological study.

    Science.gov (United States)

    Valtolina, Chiara; Robben, Joris H; Favier, Robert P; Rothuizen, Jan; Grinwis, Guy Cm; Schotanus, Baukje A; Penning, Louis C

    2018-05-01

    Objectives The aim of this study was to describe the cellular and stromal components of the hepatic progenitor cell niche in feline hepatic lipidosis (FHL). Methods Immunohistochemical staining for the progenitor/bile duct marker (K19), activated Kupffer cells (MAC387), myofibroblasts (alpha-smooth muscle actin [α-SMA]) and the extracellular matrix component laminin were used on seven liver biopsies of cats with FHL and three healthy cats. Double immunofluorescence stainings were performed to investigate co-localisation of different cell types in the hepatic progenitor cell (HPC) niche. Results HPCs, Kupffer cells, myofibroblasts and laminin deposition were observed in the liver samples of FHL, although with variability in the expression and positivity of the different immunostainings between different samples. When compared with the unaffected cats where K19 positivity and minimal α-SMA and laminin positivity were seen mainly in the portal area, in the majority of FHL samples K19 and α-SMA-positive cells and laminin positivity were seen also in the periportal and parenchymatous area. MAC387-positive cells were present throughout the parenchyma. Conclusions and relevance This is a preliminary morphological study to describe the activation and co-localisation of components of the HPC niche in FHL. Although the HPC niche in FHL resembles that described in hepatopathies in dogs and in feline lymphocytic cholangitis, the expression of K19, α-SMA, MAC387 and lamin is more variable in FHL, and a common pattern of activation could not be established. Nevertheless, when HPCs were activated, a spatial association between HPCs and their niche could be demonstrated.

  6. Proceedings of the DAE-BRNS fourth interdisciplinary symposium on materials chemistry

    International Nuclear Information System (INIS)

    Tyagi, D.; Banerjee, A.M.; Bhattacharyya, K.; Nigam, S.; Varma, S.; Tripathi, A.K.; Das, D.

    2012-12-01

    This symposium covers almost all the contemporary research areas of materials chemistry like materials for energy conversion, biomaterials, carbon based materials, chemical sensors, fuel cell materials and other electro-ceramics, polymers and soft condensed matters, thin films and surface chemistry, organic and organometallics, high purity materials, nanomaterials and clusters to acquaint ourselves with the advancement made in these emerging areas. Topics like nuclear materials, magnetic materials, catalysis and computational materials chemistry continue to be important facet of ISMC series of symposia. Papers relevant to INIS are indexed separately

  7. Proceedings of the symposium on 'radiation research in life science'

    International Nuclear Information System (INIS)

    Ikushima, Takaji

    1993-06-01

    This report is the collection of the papers presented at the title symposium on radiation research in life science. The themes included in this report are as follows: (1) cellular aging process, (2) senescence gene and cellular immortalization, (3) molecular mechanism of replicative senescence, (4) programmed cell death during differentiation, (5) thymocyte apoptosis, (6) neuronal death, (7) apoptosis by HIV infection, (8) apoptosis and immunology, (9) radiation induced apoptosis, and so on. Separate abstract was prepared for 1 of the papers in this report. The remaining 10 papers were considered outside the subject scope of INIS. (J.P.N.)

  8. NATO Symposium entitled "Symposium on the Study of Motion Perception : Recent Developments and Applications"

    CERN Document Server

    Wagenaar, Willem; Leibowitz, Herschel

    1982-01-01

    From August 24-29, 1980 the international "Symposium on the Study of Motion Perception; Recent Developments and Applications", sponsored by NATO and organized by the editors of this book, was held in Veldhoven, the Netherlands. The meeting was attended by about eighty scholars, including psychologists, neurologists, physicists and other scientists, from fourteen different countries. During the symposium some fifty research papers were presented and a series of tutorial review papers were read and discussed. The research presentations have been published in a special issue of the international journal of psychonomics "Acta Psychologica" (Vol. 48, 1981). The present book is a compilation of the tutorial papers. The tutorials were arranged around early versions of the chapters now appearing in this book. The long discussions at the Veldhoven tutorial sessions resulted in extensive revisions of the texts prior to this publication. Unfortunately this led to a delay in publication, but we feel that this was justifi...

  9. Proceedings of Waseda international symposium on fundamental physics. New perspectives in quantum physics

    International Nuclear Information System (INIS)

    Ohba, Ichiro; Aizawa, Yoji; Daishido, Tsuneaki; Kurihara, Susumu; Maeda, Kei-ichi; Nakazato, Hiromichi; Tasaki, Shuichi; Yuasa, Kazuya

    2003-11-01

    Waseda International Symposium on Fundamental Physics - New Perspectives in Quantum Physics - was held on November 12-15, 2002 at International Conference Hall (IBUKA HALL), Waseda University, Tokyo, Japan. This symposium was organized to provide an opportunity to verify fundamental physics attainments and to discuss new prospectives in quantum physics in the 21st century. These themes of the symposium were reexamined from all aspects in terms of important key words of the symposium, fundamental quantum theory, quantum coherence and decoherence, quantum chaos, time symmetry breaking, Bose-Einstein condensation and quantum information and computation. Separate abstracts were presented for 12 of the papers in this report. The remaining 40 were considered outside the subject scope of INIS. (J.P.N.)

  10. Symposium on engineering with nuclear explosives. Proceedings. Volume 2

    International Nuclear Information System (INIS)

    1970-05-01

    This symposium on 'Engineering with Nuclear Explosives' reports to the Plowshare community, both national and international, the progress achieved since April 1964, the date of the Third Plowshare Symposium. In structuring the technical presentations, contributions of broadest interest were placed at the beginning, thus forming a common base of current information and applied science understanding developed in support of Plowshare technology. Sessions of speciality or pertaining to specific areas of application and engineering follow logically in the program. The Plenary Session reviewed the current status of the Plowshare Program from the technical, government, and industrial points of view. The 112 papers presented at 15 technical sessions covered all technical aspects of the Plowshare Program. The conference summary reviewed principal themes, areas of significant advance, and subjects requiring further attention that emerged during the technical conference. This proceedings is the record of the symposium

  11. Symposium on engineering with nuclear explosives. Proceedings. Vol. 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1970-05-01

    This symposium on 'Engineering with Nuclear Explosives' reports to the Plowshare community, both national and international, the progress achieved since April 1964, the date of the Third Plowshare Symposium. In structuring the technical presentations, contributions of broadest interest were placed at the beginning, thus forming a common base of current information and applied science understanding developed in support of Plowshare technology. Sessions of speciality or pertaining to specific areas of application and engineering follow logically in the program. The Plenary Session reviewed the current status of the Plowshare Program from the technical, government, and industrial points of view. The 112 papers presented at 15 technical sessions covered all technical aspects of the Plowshare Program. The conference summary reviewed principal themes, areas of significant advance, and subjects requiring further attention that emerged during the technical conference. These proceedings are the record of the symposium.

  12. Symposium on engineering with nuclear explosives. Proceedings. Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1970-05-15

    This symposium on 'Engineering with Nuclear Explosives' reports to the Plowshare community, both national and international, the progress achieved since April 1964, the date of the Third Plowshare Symposium. In structuring the technical presentations, contributions of broadest interest were placed at the beginning, thus forming a common base of current information and applied science understanding developed in support of Plowshare technology. Sessions of speciality or pertaining to specific areas of application and engineering follow logically in the program. The Plenary Session reviewed the current status of the Plowshare Program from the technical, government, and industrial points of view. The 112 papers presented at 15 technical sessions covered all technical aspects of the Plowshare Program. The conference summary reviewed principal themes, areas of significant advance, and subjects requiring further attention that emerged during the technical conference. This proceedings is the record of the symposium.

  13. Symposium on engineering with nuclear explosives. Proceedings. Vol. 1

    International Nuclear Information System (INIS)

    1970-05-01

    This symposium on 'Engineering with Nuclear Explosives' reports to the Plowshare community, both national and international, the progress achieved since April 1964, the date of the Third Plowshare Symposium. In structuring the technical presentations, contributions of broadest interest were placed at the beginning, thus forming a common base of current information and applied science understanding developed in support of Plowshare technology. Sessions of speciality or pertaining to specific areas of application and engineering follow logically in the program. The Plenary Session reviewed the current status of the Plowshare Program from the technical, government, and industrial points of view. The 112 papers presented at 15 technical sessions covered all technical aspects of the Plowshare Program. The conference summary reviewed principal themes, areas of significant advance, and subjects requiring further attention that emerged during the technical conference. These proceedings are the record of the symposium

  14. Book Symposium: Duncan Pritchard, Epistemic Angst (Princeton University Press, 2015, xiii + 236 pages

    Directory of Open Access Journals (Sweden)

    Duncan Pritchard

    Full Text Available ABSTRACT This book symposium features three critical pieces dealing with Duncan Pritchard's book, 'Epistemic Angst'; the symposium also contains Pritchard's replies to his critics.

  15. Proceedings of KURRI symposium on criticality safety

    International Nuclear Information System (INIS)

    Nishina, Kojiro; Kanda, Keiji

    1984-01-01

    On August 8, 1984, at the Reactor Application Center of the Research Reactor Institute, Kyoto University, the symposium on criticality safety was held, and 81 participants from various fields of reactor physics, nuclear fuel cycle engineering, reactor chemistry, nuclear chemistry, health physics and so on discussed the problem. The gists of the presentation are collected in this report. The contents are the techniques of evaluating criticality safety in respective fuel facilities, the system of control and its concept, the course and plan of the research on criticality safety in Japan and foreign countries, the techniques of determining multiplication factor and so on, and the review of present status, the pointing-out of problems and the report of new techniques were made. The measures coping with criticality safety have been mostly to meet urgent demand, but its fundamental examination and long term research should be carried out. This symposium was planned as the preparation for such research project, and favorable comment was given by the participants. In the next symposium, it is considered better to limit the themes and to allot more time to respective lectures. (Kako, I.)

  16. Proceedings of the international symposium: Transfer of radionuclides in biosphere. Prediction and assessment

    International Nuclear Information System (INIS)

    Amano, Hikaru

    2003-09-01

    The International Symposium : Transfer of Radionuclides in Biosphere - Prediction and Assessment was held at Mito on the 18th and 19th of December 2002. This International Symposium was organized by the Interchange Committee on Radionuclide Transfer in Soil Ecosphere. This project is the 3rd Phase Crossover Research, which is engaged in cooperation with five organizations: Japan Atomic Energy Research Institute (JAERI), Meteorological Research Institute (MRI), National Institute of Radiological Sciences (NIRS), RIKEN (Institute of Physical and Chemical Research) and Institute for Environmental Sciences (IES). The main objective of this symposium is to discuss and exchange recent findings and ideas in the area of the behavior and transfer of radionuclides in biosphere. One of the important topics in this symposium is to discuss a suitable transfer model and transfer parameters which may be adapted for Southeast Asian countries including Japan, as environmental conditions and foodstuffs in this region are significantly different from those in Europe and North America. It will be hoped that the predictions of the consequences of the release of radionuclides in the terrestrial environment will be improved through exchange of views and new results. The symposium consisted of 12 invited lectures and 44 poster presentations. The 117 participants attended the symposium, including 19 foreigners coming from 12 countries. (author)

  17. CONFERENCE REVIEW:V. International Educational Technology Symposium

    Directory of Open Access Journals (Sweden)

    Reviewed by Mubin KIYICI

    2005-10-01

    Full Text Available 167V. International Educational Technology SymposiumWas held in Sakarya UniversityBetween 21 – 23 September 2005Reviewed by Mubin KIYICISakarya Universitymkiyici@anadolu.edu.trV. International Educational Technology Symposium was held in Sakarya University heldbetween 21 – 23 September 2005 by cooperation with Eastern Mediterranean University,Louisiana State University, Governors State University and Ohio University, and TOJET(The Turkish Online Journal of Educational Technology journal, at Sakarya UniversityCampus. Assoc. Prof. Dr. Aytekin ISMAN who was conference coordinator and Editor inchief of TOJET spoke at the opening ceremony of symposium. His speech was related todiffusion of distance education and diffusion of usage educational technology. And thenProf. Dr. Mehmet DURMAN who is Rector of Sakarya University, talked about aapplications of Distance Education which is applied by Sakarya University and educationaltechnology applications in Tukey. His Speech is here:168Dear GuestsWelcome to the “5th International Educational Technology ConferenceIETC/EGİTEK 2005. It is an international educational activity for academics,teachers and educators. This conference is now a well known educationaltechnology event and the number of paper submissions and attendeesincrease every year.This year, IETC-2005 received 268 applications. The conference academicadvisory board accepted 209 applications.IETC-2005 promotes the development and dissemination of theoreticalknowledge, conceptual research, and professional knowledge throughconference activities, the conference proceeding book, and the TurkishOnline Journal of Educational Technology (TOJET. Its focus is to create anddisseminate knowledge about the use instructional technology for learningand teaching in education.The main theme of IETC-2005 is distance education. Distance education is adelivery system of teaching and learning, when the teacher and the studentare separated by physical distance

  18. WE-NET Hydrogen Energy Symposium proceedings; WE-NET suiso energy symposium koen yokoshu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-02-24

    The research and development of WE-NET (World Energy Network) was started in 1993 as a NEDO (New Energy and Industrial Technology Development Organization) project in the New Sunshine Program of Agency of Industrial Science and Technology, Ministry of International Trade and Industry, and aims to contribute to the improvement of global environment and to ease the difficult energy supply/demand situation. The ultimate goal of WE-NET is the construction of a global-scale clean energy network in which hydrogen will be produced from renewable energies such as water and sunshine for distribution to energy consuming locations. Experts are invited to the Symposium from the United States, Germany, and Canada. Information is collected from the participants on hydrogen energy technology development in the three countries, the result of the Phase I program of WE-NET is presented to hydrogen energy scientists in Japan, and views and opinions on the project are collected from them. Accommodated in the above-named publication are 30 essays and three special lectures delivered at the Symposium. (NEDO)

  19. 1993 Proceedings volume 1--Contamination control; symposium on minienvironments; symposium on biocontamination control

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    Volume 1 contains the proceedings from three symposia. Contamination Control includes the following topics: Atmospheric pressure ionization mass spectroscopy (APIMS) applications; APIMS development; contamination control in cleanroom air; defect reduction in semiconductor processes; contamination control in the aerospace industry; filtration of gases; ultrapure chemical and DI water; filtration of chemicals; wafer cleaning/trace contaminant effects; wafer cleaning techniques; detection of particles in UHP fluids; detection of surface particles; modeling contamination; detection of surface organics; modeling, particle transport, deposition, and removal; and detection of surface metallics. Symposium on Minienvironments includes the following: design of minienvironments; robotics and I/O transport; testing, methods, and standards. The Symposium on Biocontamination Control includes the following: microbial CC facility requirements in pharmaceutical, biological, and medical device manufacture; cleaning and disinfecting methods and devices for bio CC; biocontamination control devices, methodology, and standards, airborne and surface microbial monitoring methods and devices; and regulatory issues in bio CC--present and future. All papers within the scope of the Energy Data Base have been processed separately for inclusion on the data base

  20. 14. European cosmic ray symposium. Symposium program and abstracts

    International Nuclear Information System (INIS)

    1994-08-01

    The abstracts of the 14. European Cosmic Ray Symposium are presented. The papers cover a large variety of topics in cosmic ray physics, both from the theoretical and the experimental point of view. Sun physics, and the effects on the inner heliosphere, the composition, and the properties of the primary and secondary cosmic radiation, galactic acceleration and the results of accelerator physics relevant to cosmic radiation physics, and the description and the results of large detector systems are presented. 63 items are indexed for INIS database. (K.A.)

  1. Coal dust symposium

    Energy Technology Data Exchange (ETDEWEB)

    1981-03-01

    This paper gives a report of the paper presented at the symposium held in Hanover on 9 and 10 February 1981. The topics include: the behaviour of dust and coal dust on combustion and explosion; a report on the accidents which occurred at the Laegerdorf cement works' coal crushing and drying plant; current safety requirements at coal crushing and drying plant; and coal crushing and drying. Four papers are individually abstracted. (In German)

  2. Proceedings of the 9th symposium on advanced photon research

    International Nuclear Information System (INIS)

    2010-03-01

    The 9th Symposium on Advanced Photon Research was held at Kansai Photon Science Institute, Japan Atomic Energy Agency (JAEA-KPSI) in Kizugawa, Kyoto on July 31- August 1, 2008. This report consists of invited and contributed papers presented at the oral and poster sessions in The Symposium. The 25 of the presented papers are indexed individually. (J.P.N.)

  3. Proceedings of the 21. European Cosmic Ray Symposium

    International Nuclear Information System (INIS)

    Kiraly, P.; Kudela, K.; Wolfendale, A. W.

    2008-09-01

    Scientific symposium deals with problems of cosmic ray. The Symposium included the following sessions: (1): Relationship of cosmic rays to the environment; (2) Energetic particles and the magnetosphere of the Earth; (3) Energetic particles in the heliosphere; (4) Solar-terrestrial effects on different time scales; (5) Cosmic rays below the knee; (6) Cosmic rays above the knee (7) High energy interactions; (8) GeV and TeV gamma ray astronomy; (9) European projects related to cosmic rays; Future perspectives. Proceedings contains 122 papers dealing with the scope of INIS.

  4. Proceedings of a symposium about PEARL in Augsburg

    International Nuclear Information System (INIS)

    1977-05-01

    Both, the PDV Project Management of the Gesellschaft fuer Kerforschung mbH, Karlsruhe, and the VDI/VDE-Gesellschaft Mess- und Regelungstechnik, were organizing on March 9, 1977, a public symposium about PEARL, the unified realtime programming language in the Federal Republic of Germany. This report contains papers of speeches given at the symposium about the following topics: 1) The sponsoring of PEARL within the Project PDV (history, status, future, standardization); 2) PEARL as compared with other realtime languages; 3) experience with present PEARL subsets (both in laboratory and industrial environment). (orig.) [de

  5. I Symposium of Elite Performance in Combat Sports

    Directory of Open Access Journals (Sweden)

    Montse C. Ruiz

    2017-07-01

    Full Text Available This report presents a summary of the I Symposium of Elite Performance in Combat Sports held in Madrid, May 27, 2017. The symposium, organized by the Faculty of Sport Sciences-INEF of the Polytechnic University of Madrid, aimed to bring science closer to practice. A panel of highly successful athletes involved in karate, fencing, and taekwondo shared their experiences. The speakers presented crucial topics for an optimal preparation and high level performance such as strength training, sport psychology, brain maturation, sports nutrition, competition planning, sport injuries, and perceptual-decision making training.

  6. Proceedings of the solid state physics symposium. Vol. 34C

    International Nuclear Information System (INIS)

    1991-12-01

    This volume contains the proceedings of the Solid State Physics Symposium held at Varanasi during December 21 to 24, 1991. The topics discussed in the symposium were : (a) Phonon physics, (b) Electron states and electronic properties, (c) Magnetism and magnetic properties, (d) Semiconductor physics, (e) Physics of defects and disordered materials, (f) Transport properties, (g) Superconductivity and superfluidity, (h) Liquid crystals and plastic crystals, (i) Phase transitions and critical phenomena, (j) Surface and interface physics, (k) Non-linear dynamics, instabilities and chaos, (l) Resonance studies and relaxation phenomena, (m) Solid state devices, techniques and instrumentation. Three seminars on topics : (i) High T c superconductors, (ii) Soft matter, and (iii) Physics and technology of interfaces were also held during the symposium. (M.K.V.N.)

  7. Splenic red pulp macrophages are intrinsically superparamagnetic and contaminate magnetic cell isolates.

    Science.gov (United States)

    Franken, Lars; Klein, Marika; Spasova, Marina; Elsukova, Anna; Wiedwald, Ulf; Welz, Meike; Knolle, Percy; Farle, Michael; Limmer, Andreas; Kurts, Christian

    2015-08-11

    A main function of splenic red pulp macrophages is the degradation of damaged or aged erythrocytes. Here we show that these macrophages accumulate ferrimagnetic iron oxides that render them intrinsically superparamagnetic. Consequently, these cells routinely contaminate splenic cell isolates obtained with the use of MCS, a technique that has been widely used in immunological research for decades. These contaminations can profoundly alter experimental results. In mice deficient for the transcription factor SpiC, which lack red pulp macrophages, liver Kupffer cells take over the task of erythrocyte degradation and become superparamagnetic. We describe a simple additional magnetic separation step that avoids this problem and substantially improves purity of magnetic cell isolates from the spleen.

  8. The paediatric cardiac centre for Africa--proceedings of the March 2012 symposium.

    Science.gov (United States)

    Kinsley, Robin H; Edwin, Frank; Entsua-Mensah, Kow

    2013-04-01

    The Pediatric Cardiac Centre for Africa (PCCA) was opened by national patron Mr Nelson Mandela on November 7, 2003. In 2008, the Centre's international pediatric cardiac symposium was introduced as a learning forum for pediatric cardiac surgeons and cardiologists in the continent. The symposium has consistently grown in attendance and attracted distinguished leaders in the field. The 2012 symposium featured Dr. Thomas Spray of Children's Hospital of Philadelphia, Dr. David Barron of Birmingham Children's Hospital, and Dr. John Brown of Indiana University School of Medicine as guest speakers. Experience of the Fontan procedure, the small aortic root, hypoplastic left heart syndrome, right ventricular outflow tract reconstruction, transposition of the great arteries, and interrupted aortic arch were the highlights of the symposium. In the "African Corner," centers in South Africa, Ghana, and Angola presented work done from across the African continent.

  9. Proceedings of the first symposium on science of hadrons under extreme conditions

    Energy Technology Data Exchange (ETDEWEB)

    Chiba, Satoshi; Maruyama, Toshiki [eds.

    1999-08-01

    The first symposium on Science of Hadrons under Extreme Conditions, organized by the Research Group for Hadron Science, Advanced Science Research Center, was held at Tokai Research Establishment of JAERI on March 11 and 12, 1999. The symposium was devoted for discussions and presentations of research results in wide variety of fields such as observation of X-ray pulsars, theoretical studies of nuclear matter, nuclear structure, low- and high-energy nuclear reactions and QCD. Thirty seven papers on these topics presented at the symposium are indexed individually. (J.P.N.)

  10. 'HTA for Crisis': sharing experiences during the 7th EBHC Symposium.

    Science.gov (United States)

    Wladysiuk, Magdalena; Tabor, Anna; Godman, Brian

    2013-02-01

    The Central and Eastern European Society of Technology Assessment in Health Care was founded in Krakow, Poland in 2003. On October 8th and 9th, the 7th symposium took place titled 'HTA for Crisis'. This meeting was attended by over 250 decision makers, evidence-based specialists, healthcare managers, commercial company personnel and experts. The symposium was principally divided into four main themes: insurance in times of crisis; importance of pricing of health services in times of crisis; managing welfare benefits in times of crisis and Health Technology Assessment in crisis-laden countries. The symposium finished by debating potential ways forward for healthcare systems in times of crisis.

  11. International symposium on clusters and nanomaterials (energy and life-sciences applications)

    Energy Technology Data Exchange (ETDEWEB)

    Jena, Purusottam [Virginia Commonwealth Univ., Richmond, VA (United States)

    2017-02-09

    The International Symposium on Clusters and Nanomaterials was held in Richmond, Virginia during October 26-29, 2015. The symposium focused on the roles clusters and nanostructures play in solving outstanding problems in clean and sustainable energy and life sciences applications; two of the most important issues facing science and society. Many of the materials issues in renewable energies, environmental impacts of energy technologies as well as beneficial and toxicity issues of nanoparticles in health are intertwined. Realizing that both fundamental and applied materials issues require a multidisciplinary approach the symposium provided a forum by bringing researchers from physics, chemistry, materials science, and engineering fields to share their ideas and results, identify outstanding problems, and develop new collaborations. Clean and sustainable energy sessions addressed challenges in production, storage, conversion, and efficiency of renewable energies such as solar, wind, bio, thermo-electric, and hydrogen. Environmental issues dealt with air- and water-pollution and conservation, environmental remediation and hydrocarbon processing. Topics in life sciences included therapeutic and diagnostic methods as well as health hazards attributed to nanoparticles. Cross-cutting topics such as reactions, catalysis, electronic, optical, and magnetic properties were also covered. The symposium attracted 132 participants from 24 countries in the world. It featured 39 invited speakers in 14 plenary sessions, in addition to one key-note session. Eighty-five contributed papers were presented in two poster sessions and 14 papers from this list were selected to be presented orally at the end of each session to highlight hot topics. Papers presented at the symposium were reviewed and published in SPIE so that these can reach a wide audience. The symposium was highly interactive with ample time allotted for discussions and making new collaborations. The participants’ response

  12. Symposium "Balans in Duurzaamheid"; 4 juni 2002 Rolzaal, Binnenhof, Den Haag

    NARCIS (Netherlands)

    Duijvenbooden W van; Poolman AM; MNP/Sector 5

    2002-01-01

    The symposium on 'Balance in Sustainability' was organised by the Office for Environmental Assessment (MNP) of the RIVM in The Hague on June 4th 2002. Mr Van Egmond, Director of the MNP started off the symposium with a presentation on the structure and the content of a 'Balance in Sustainability'.

  13. EDITORIAL: Nobel Symposium 148: Graphene and Quantum Matter Nobel Symposium 148: Graphene and Quantum Matter

    Science.gov (United States)

    Niemi, Antti; Wilczek, Frank; Ardonne, Eddy; Hansson, Hans

    2012-01-01

    The 2010 Nobel Symposium on Graphene and Quantum Matter, was held at the Grand Hotel in Saltsjöbaden south of Stockholm on 27-31 May. The main theme of the meeting was graphene, and the symposium turned out to be very timely: two of the participants, Andre Geim and Kanstantin Novoselov returned to Stockholm less then six months later to receive the 2010 Nobel Prize in Physics. In these proceedings leading experts give up-to-date, historical, experimental, theoretical and technological perspectives on the remarkable material graphene, and several papers also make connections to other states of quantum matter. Saltsjöbaden is beautifully situated in the inner archipelago of Stockholm. It provided a pleasant setting for the talks and the ensuing discussions that took place in an enthusiastic and friendly atmosphere. The social programme included a boat trip in the light summer night and a dinner at the renowned Grand Hotel. These proceedings are ordered thematically, starting with historical overviews, followed by first experimental and then theoretical papers on the physics of graphene. Next are several papers addressing more general topics in quantum matter and finally contributions on the technological applications of graphene. We hope that this volume will serve as a source of knowledge and inspiration for any physicist interested in graphene, and at the same time provide a snapshot of a young field of research that is developing at very high speed. We are grateful to Marja Fahlander for excellent administrative support, and to the Nobel Foundation who funded the symposium.

  14. 7th international symposium on internal combustion diagnostics. Proceedings; 7. Internationales Symposium fuer Verbrennungsdiagnostik. Beitraege

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    At one time combustion pressure indicating was the ''trigger'' for this symposium, and today it still serves as the basis for continued investigation of combustion phenomena. It now finds application throughout the development process, as more sophisticated analysis of conventional signals is possible. Understanding of localized combustion phenomena is substantially simplified by means of optical diagnostic methods, the application of which has reached a certain level of standardization. The presentations will cover specific topics including fuel spray analysis, ignition events and information about gas mixtures. The comparison and combination of results from measurement and simulation shed light on the complex processes in the combustion chamber. What's more, the linkage of two complementary methods offers substantial cost savings through reductions in test hardware and shorter development times. Focused application of all of the available tools allows us better to understand combustion processes, recognize the influential parameters and derive control algorithms. The latter are subsequently to be found in engines that fulfill both regulatory requirements and customer expectations. So it is that the symposium captures the current state of the art in combustion diagnostics through a combination of indicating, optical diagnostics and simulation, and offers both the methodology expert and the engine developer the ideal platform for discussion of today's issues - and to form their own opinions on them. Anyone wanting to keep up to date in this continuously developing and ever more complex area of activity certainly can't afford to miss our symposium. (orig.)

  15. PREFACE: XXXIV Symposium on Nuclear Physics

    Science.gov (United States)

    Barrón-Palos, Libertad; Bijker, Roelof

    2011-10-01

    In the present volume of the Journal of Physics: Conference Series we publish the proceedings of the 'XXXIV Symposium on Nuclear Physics', which was held from 4-7 January 2011 at the Hacienda Cocoyoc, Morelos, Mexico. The proceedings consist of 19 contributions that were presented as invited talks at the meeting. The abstracts of all contributions, plenary talks and posters were published in the Conference Handbook. The Symposium on Nuclear Physics has a long and distinguished history. From the beginning it was intended to be a relatively small meeting designed to bring together some of the leading nuclear scientists in the field. Its most distinctive feature is to provide a forum for specialists in different areas of nuclear physics, both theorists and experimentalists, students, postdocs and senior scientists, in a relaxed and informal environment providing them with a unique opportunity to exchange ideas. From the first meeting in Oaxtepec in 1978, the Symposium has been organized every year without interruption, which makes the present Symposium the 34th in a row. The scientific program consisted of 27 invited talks and 17 posters on a wide variety of hot topics in contemporary nuclear physics, ranging from the traditional fields of nuclear structure (Draayer, Pittel, Van Isacker, Fraser, Lerma, Cejnar, Hirsch, Stránský and Rath) and nuclear reactions (Aguilera, Gómez-Camacho, Scheid, Navrátil and Yennello) to radioactive beams (Padilla-Rodal and Galindo-Uribarri), nuclear astrophysics (Aprahamian, Civitarese and Escher), hadronic physics (Bijker, Valcarce and Hess), fundamental symmetries (Liu, Barrón-Palos and Baessler) and LHC physics (Menchaca-Rocha and Paic). The high quality of the talks, the prestige of the speakers and the broad spectrum of subjects covered in the meeting, shows that nuclear physics is a very active area at the frontier of scientific research which establishes bridges between many different disciplines. Libertad Barr

  16. Diversity in the Workplace. Symposium.

    Science.gov (United States)

    2002

    Three papers comprise this symposium on diversity in the workplace. "Factors That Assist and Barriers That Hinder the Success of Diversity Initiatives in Multinational Corporations" (Rose Mary Wentling) reports that factors that assisted in the success were classified under diversity department, human, and work environment; barriers were…

  17. Annual Symposium in Electronics Packaging

    CERN Document Server

    1991-01-01

    Each May, the Continuing Education Division of the T.J.Watson School of Engineering, Applied Science and Technology at the State University of New York at Binghamton sponsors an Annual Symposium in Electronics Packaging in cooperation with local professional societies (IEEE, ASME, SME, IEPS) and UnlPEG (the University-Industry Partnership for Economic Growth.) Each volume of this Electronics Packaging Forum series is based on the the preceding Symposium, with Volume Two based on the 1990 presentations. The Preface to Volume One included a brief definition of the broad scope of the electronics packaging field with some comments on why it has recently assumed such a more prominent priority for research and development. Those remarks will not be repeated here; at this point it is assumed that the reader is a professional in the packaging field, or possibly a student of one of the many academic disciplines which contribute to it. It is worthwhile repeating the series objectives, however, so the reader will be cle...

  18. 2015 International Symposium in Statistics

    CERN Document Server

    2016-01-01

    This proceedings volume contains eight selected papers that were presented in the International Symposium in Statistics (ISS) 2015 On Advances in Parametric and Semi-parametric Analysis of Multivariate, Time Series, Spatial-temporal, and Familial-longitudinal Data, held in St. John’s, Canada from July 6 to 8, 2015. The main objective of the ISS-2015 was the discussion on advances and challenges in parametric and semi-parametric analysis for correlated data in both continuous and discrete setups. Thus, as a reflection of the theme of the symposium, the eight papers of this proceedings volume are presented in four parts. Part I is comprised of papers examining Elliptical t Distribution Theory. In Part II, the papers cover spatial and temporal data analysis. Part III is focused on longitudinal multinomial models in parametric and semi-parametric setups. Finally Part IV concludes with a paper on the inferences for longitudinal data subject to a challenge of important covariates selection from a set of large num...

  19. Summary of Numerical Modeling for Underground Nuclear Test Monitoring Symposium

    International Nuclear Information System (INIS)

    Taylor, S.R.; Kamm, J.R.

    1993-01-01

    This document contains the Proceedings of the Numerical Modeling for Underground Nuclear Test Monitoring Symposium held in Durango, Colorado on March 23-25, 1993. The symposium was sponsored by the Office of Arms Control and Nonproliferation of the United States Department of Energy and hosted by the Source Region Program of Los Alamos National Laboratory. The purpose of the meeting was to discuss state-of-the-art advances in numerical simulations of nuclear explosion phenomenology for the purpose of test ban monitoring. Another goal of the symposium was to promote discussion between seismologists and explosion source-code calculators. Presentation topics include the following: numerical model fits to data, measurement and characterization of material response models, applications of modeling to monitoring problems, explosion source phenomenology, numerical simulations and seismic sources

  20. Stainable hepatic iron in 341 African American adults at coroner/medical examiner autopsy

    Directory of Open Access Journals (Sweden)

    Acton Ronald T

    2005-01-01

    Full Text Available Abstract Background Results of previous autopsy studies indicate that increased hepatic iron stores or hepatic iron overload is common in African Americans dying in hospitals, but there are no reports of hepatic iron content in other cohorts of African Americans. Methods We investigated the prevalence of heavy liver iron deposition in African American adults. Using established histochemical criteria, we graded Perls' acid ferrocyanide-reactive iron in the hepatocytes and Kupffer cells of 341 consecutive African American adults who were autopsied in the coroner/medical examiner office. Heavy staining was defined as grade 3 or 4 hepatocyte iron or grade 3 Kupffer cell iron. Results There were 254 men and 85 women (mean age ± 1 SD: 44 ± 13 y vs. 48 ± 14 y, respectively; p = 0.0255; gender was unstated or unknown in two subjects. Approximately one-third of subjects died of natural causes. Heavy staining was observed in 10.2% of men and 4.7% of women. 23 subjects had heavy hepatocyte staining only, six had heavy Kupffer cell staining only, and one had a mixed pattern of heavy staining. 15 subjects had histories of chronic alcoholism; three had heavy staining confined to hepatocytes. We analyzed the relationships of three continuous variables (age at death in years, hepatocyte iron grade, Kupffer cell iron grade and two categorical variables (sex, cause of death (natural and non-natural causes in all 341 subjects using a correlation matrix with Bonferroni correction. This revealed two positive correlations: hepatocyte with Kupffer cell iron grades (p Conclusions The present results confirm and extend previous observations that heavy liver iron staining is relatively common in African Americans. The pertinence of these observations to genetic and acquired causes of iron overload in African Americans is discussed.

  1. Proceedings of the 3rd international symposium on material chemistry in nuclear environment (MATERIAL CHEMISTRY '02)

    International Nuclear Information System (INIS)

    2003-03-01

    The volume contains all presented papers during the 3rd International Symposium on Material Chemistry in Nuclear Environment: MATERIAL CHEMISTRY 02 (MC'02), held March 13-15, 2002. The purpose of this symposium is to provide an international forum for the discussion of recent progress in the field of materials chemistry in nuclear environments. This symposium intends to build on the success of the previous symposiums held in Tsukuba in 1992 and 1996. The topics discussed in the symposium MC'02 are Chemical Reaction and Thermodynamics, Degradation Phenomena, New Characterization Technology, Fabrication and New Materials, Composite Materials, Surface Modification, and Computational Science. The 61 of the presented papers are indexed individually. (J.P.N.)

  2. Overview of symposium on storage of spent fuel from power reactors

    International Nuclear Information System (INIS)

    Bonne, A.; Crijns, M.J.; Dyck, H.P.

    2001-01-01

    An International Symposium on Storage of Spent Fuel from Power Reactors was held in Vienna from 9-13 November 1998. The Symposium was organized by the International Atomic Energy Agency in co-operation with the OECD Nuclear Energy Agency. Of the one hundred sixty participants registered, one hundred twenty-five (including 3 observers) representing 35 countries and 4 international organizations, attended the Symposium. 20 participants from developing countries received Agency's grants. During 4 main Sessions, 44 oral presentations of papers were made and subsequent discussions held. At a poster session 13 papers were presented. This paper will give an overview of the Symposium. The Symposium gave an opportunity to exchange information on the state of art and prospects of spent fuel storage, to discuss the worldwide situation and the major factors influencing the national policies in this field and to identify the most important directions that national efforts and international co-operation in this area should take. It was obvious from the papers presented and the discussions that the handling and storage of spent fuel is continuously taking place safely. Dominant messages retrieved from the Symposium are that the primary spent fuel management solution for the next decades will be interim storage, the duration time of interim storage becomes longer than earlier anticipated and the storage facilities will have to be designed for receiving also spent fuel from advanced fuel cycle practices (i.e. high burnup and MOX spent fuel). It was noted that the handling and storage of spent fuel is a mature technology and meets the stringent safety requirements applicable in the different countries. The changes in nuclear policy and philosophy across the world, and practical considerations, have made interim storage a real necessity in the nuclear power industry. (author)

  3. NuPEER Dijon 2005 Symposium. Ageing issues in nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Emond, David (ed.) [BCCN, Autorite de Surete Nucleaire, ASN, 6, place du Colonel Bourgoin, 75572 Paris Cedex 12 (France)

    2005-07-01

    The French Nuclear Safety Authority (ASN) organized an international symposium on regulatory aspects of ageing issues for nuclear pressure equipment. The ageing of nuclear pressure equipment is an issue of growing importance for nuclear regulators and material experts worldwide as age-related degradation of major pressure-retaining components challenges the remaining operating life of nuclear power plants. This symposium aimed at providing a forum for technical exchange among the staffs responsible for nuclear pressure equipment within the safety authorities and the associated expertise organisations. The contents of the symposium is as follows: 1. Control and supervision of safety of nuclear pressure equipment in France and abroad; 1.1. Position of the French Nuclear Safety Authority (1 paper); 1.2. Regulatory practices worldwide (4 papers); 1.3. Licence renewal: Field experience (2 papers); 1.4. Role of international organisations (1 paper); 2. Management of equipment and materials: From design to degradation mechanisms; 2.1. Operation and equipment (4 papers); 2. Evolution of materials (4 papers); 2.3. Fatigue degradation mechanisms (3 papers); 2.4. Contribution of research and development (4 papers); 3. In-service inspection: Evolutions, methods and strategies; 3.1. Methods and evolution (1 paper); 3.2. Qualification of methods (2 papers); 3.3. Surveillance strategies (2 papers); 4. Testimonies and points of view of utilities (3 papers); 5. Ageing issues taken into account in non nuclear fields (2 papers). The symposium began with workshops devoted to: Operation and equipment; Behaviour of materials; Fatigue degradations; Contributions of research and development. The symposium continued with plenary session that addressed the following issues: Control and supervision of safety of nuclear pressure equipment; Role of international organisations; In-service inspection: Objectives, methods and strategies; Point of view of utilities; Technical summary and

  4. Proceedings of DAE-BRNS life sciences symposium 2011 on advances in molecular and cell biology of stress response

    International Nuclear Information System (INIS)

    2011-01-01

    This series of symposia in life sciences was initiated for the purpose of facilitating strong interactions among the national research fraternity working in the areas of bio-medical and agricultural sciences of relevance and interest for the Department of Atomic Energy, Government of India. Dedicated research efforts in the Bhabha Atomic Research Centre and other DAE institutions for nearly four decades have not only resulted in the development of technologies and products to improve the quality of human life, but have made impactful contributions in several contemporary areas in basic biological sciences. It is natural that keep visiting certain themes more than once. Biology of stress response is one such theme. The first symposium in the series was devoted to this field. And six years is long enough a time for catching up with the new developments. Stress to a system at equilibrium induces homeostatic mechanisms that ameliorate the stress. Entire living world, from microbes to man, have evolved such response mechanisms. Often a given battery of responsive genes may take care of more than one stresses and there may also be some redundancy in signalling or effector pathways to a response. Oxidative stress in one of the most common stresses that most living systems have to endure. Such a stress could be induced by a wide variety of insults including ionizing radiation, visible light, antibiotics, xenobiotics, metal ions, environmental pollutants, carcinogens, infectious agents etc. It may contribute to some inflammatory and autoimmune diseases. It also plays an important role in killing of intracellular pathogens. In recent years mechanistic details of body's antioxidant defences are being increasingly revealed. Even more interesting are the new findings that suggest that prooxidants may induce an adaptive response to help cells survive against death induced by higher levels of reactive oxygen species (ROS). The role of prosurvival transcription factors like NRF-2

  5. 2016 Gilbert W. Beebe symposium

    Science.gov (United States)

    The National Academies of Sciences, Engineering, and Medicine is hosting the 2016 Gilbert W. Beebe Symposium. Its focus will be on commemorating the 1986 Chernobyl nuclear reactor accident and discussing the achievements of 30 years of studies on the radiation health effects following the accident and future research directions.

  6. Proceedings of the symposium on advanced measurement techniques and instrumentation: abstract book

    International Nuclear Information System (INIS)

    Kale, Y.B.; Kushwaha, M.; Somkuwar, S.P.; Ajayakumar, S.; Sampathkumar, R.

    2011-01-01

    In order to consolidate the existing knowledge base and further to focus on the future directions of the field of advanced measurement techniques and instrumentation, Bhabha Atomic Research Centre has organized a three-day symposium on 'Advanced Measurement Techniques and Instrumentation' at Multi Purpose Hall, Training School Hostel, Anushaktinagar, Mumbai during February 02-04, 2011. The symposium is aimed at providing a forum to discuss the emerging trends and challenges ahead in the important area of measurement science and technology. This is a unique symposium, which brings together scientists and engineers from all disciplines and provides them a platform for close interaction to exchange ideas, methodologies and expertise, which is extremely important for synergic growth of this field. The symposium consists of 27 talks, which include keynote address, plenary and invited talks, and 63 contributory papers. The abstracts of these papers are brought to you in this volume. Readers may observe that the scientific programme of the symposium covers a wide ranging issues including advanced scientific concepts in measurements, instrumentation strategies, mathematical techniques and development of devices for applications in fundamental physics, astrophysics, fusion plasmas, nuclear reactors, accelerators, environment, chemical and biological sciences, and national security. Papers relevant to INIS are indexed separately

  7. Proceedings of the 2002 symposium on nuclear data

    Energy Technology Data Exchange (ETDEWEB)

    Ohsawa, Takaaki [Kinki Univ., Higashi-Osaka, Osaka (Japan); Fukahori, Tokio [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2003-06-01

    The 2002 Symposium on Nuclear Data was held at Tokai Research Establishment, Japan Atomic Energy Research Institute (JAERI), on 21st and 22nd of November 2002. Japanese Nuclear Data Committee and Nuclear Data Center, JAERI organized this symposium. In the oral sessions, presented were 18 papers on topics of release of JENDL-3.3, requests from users, status of FP nuclear data, international activities and other subjects. In the poster session, presented were 33 papers concerning experiments, evaluations, benchmark tests and on-line database on nuclear data. Those presented papers are compiled in the proceedings. (author)

  8. Proceedings of national symposium on computer applications in power plants

    International Nuclear Information System (INIS)

    1992-01-01

    The National Symposium on Computer Applications in Power Plants was organized to help promote exchange of views among scientists and engineers engaged in design, engineering, operation and maintenance of computer based systems in nuclear power plants, conventional power plants, heavy water plants, nuclear fuel cycle facilities and allied industries. About one hundred papers were presented at the Symposium. Those falling within the subject scope of INIS have been processed separately. (author)

  9. Eighth International Symposium on Recent Advances in Environmental Health Research

    Directory of Open Access Journals (Sweden)

    Paul B. Tchounwou

    2012-05-01

    Full Text Available This special issue of International Journal of Environmental Research and Public Health is dedicated to the publication of selected papers presented at the Eighth International Symposium on Recent Advances in Environmental Health Research. The Symposium was organized by Jackson State University (JSU from September 18-21, 2011 at the Marriott Hotel in Jackson, Mississippi. It was built upon the overwhelming success of seven previous symposia hosted by JSU. [...

  10. Proceedings: 19th International Nondestructive Testing and Evaluation of Wood Symposium

    Science.gov (United States)

    Robert J. Ross; Raquel Gonçalves; Xiping Wang

    2015-01-01

    The 19th International Nondestructive Testing and Evaluation of Wood Symposium was hosted by the University of Campinas, College of Agricultural Engineering (FEAGRI/UNICAMP), and the Brazilian Association of Nondestructive Testing and Evaluation (ABENDI) in Rio de Janeiro, Brazil, on September 22–25, 2015. This Symposium was a forum for those involved in nondestructive...

  11. Proceedings of 7th Symposium of the Croatian Radiation Protection Association

    Energy Technology Data Exchange (ETDEWEB)

    Barisic, D; Grahek, Z; Krajcar Bronic, I; Miljanic, S

    2008-07-01

    The 7th symposium of the Croatian Radiation Protection Association discussed the following topics: general topics; radiation dosimetry and instrumentation; biological effects of radiation; radiation protection in medicine; radioecology and radon. For each subject many investigations, experiments, examples and results are presented. International character of this symposium shows importance of these topics not only in region but world wide.

  12. Proceedings of 7th Symposium of the Croatian Radiation Protection Association

    International Nuclear Information System (INIS)

    Barisic, D.; Grahek, Z.; Krajcar Bronic, I.; Miljanic, S.

    2008-01-01

    The 7th symposium of the Croatian Radiation Protection Association discussed the following topics: general topics; radiation dosimetry and instrumentation; biological effects of radiation; radiation protection in medicine; radioecology and radon. For each subject many investigations, experiments, examples and results are presented. International character of this symposium shows importance of these topics not only in region but world wide

  13. NATO Symposium on Women and the World of Work

    CERN Document Server

    1982-01-01

    From August 4 to 8, 1980, the Science Committee of the North Atlantic Treaty Organization (NATO) sponsored the symposium, "Women and the World of Work," which was held at the Hotel Sintra Estoril in the coastal area south of Lisbon, Portugal. This symposium hatl been "in progress" since 1977 when the idea to prepare a proposal for a NATO­ sponsored symposium on the topic of women and the military was first suggested by Dr. Walter Wilkins, then Scientific Director of the Naval Health Research Center, San Diego, California. At that time and during the previous 5 years, increasing numbers of women were being recruited into military service not only in the United States but also in several NATO-allied countries. Few research projects on the utilization of women in the military had been reported in the scientific literature with the exception of work conducted at the University of Chicago and Naval Health Research Center. Several investigators, however, were identified who had recently initiated research in this ...

  14. John B. Little Center Annual Symposium

    International Nuclear Information System (INIS)

    Demple, Bruce F.

    2007-01-01

    The Annual Symposium of the John B. Little Center for Radiation Sciences and Environmental Health at the Harvard School of Public Health seeks to educate radiobiologists and biomedical scientists in related areas on the leading research related to the effects of ionizing radiation and related environmental agents in biological systems. This effort seeks to further the training of individuals in this field, and to foment productive interactions and collaborations among scientists at Harvard and with other institutions. The Symposium attracts world-class scientists as speakers, and a broad cross-section of attendees from academic, government, and industrial research centers, as well as editorial staff from leading scientific publications. In order to maintain this quality, funding to support the travel and local expenses of invited speakers is sought, along with funds to allow use of appropriate conference facilities.

  15. John B. Little Center Annual Symposium

    Energy Technology Data Exchange (ETDEWEB)

    Demple, Bruce F.

    2007-11-02

    The Annual Symposium of the John B. Little Center for Radiation Sciences and Environmental Health at the Harvard School of Public Health seeks to educate radiobiologists and biomedical scientists in related areas on the leading research related to the effects of ionizing radiation and related environmental agents in biological systems. This effort seeks to further the training of individuals in this field, and to foment productive interactions and collaborations among scientists at Harvard and with other institutions. The Symposium attracts world-class scientists as speakers, and a broad cross-section of attendees from academic, government, and industrial research centers, as well as editorial staff from leading scientific publications. In order to maintain this quality, funding to support the travel and local expenses of invited speakers is sought, along with funds to allow use of appropriate conference facilities.

  16. SYMPOSIUM: Rare decays

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1989-04-15

    Late last year, a symposium entitled 'Rare Decays' attracted 115 participants to a hotel in Vancouver, Canada. These participants were particle physicists interested in checking conventional selection rules to look for clues of possible new behaviour outside today's accepted 'Standard Model'. For physicists, 'rare decays' include processes that have so far not been seen, explicitly forbidden by the rules of the Standard Model, or processes highly suppressed because the decay is dominated by an easier route, or includes processes resulting from multiple transitions.

  17. PREFACE: Padjadjaran Earth Dialogues: International Symposium on Geophysical Issues, PEDISGI

    Science.gov (United States)

    Rosandi, Y.; Urbassek, H. M.; Yamanaka, H.

    2016-01-01

    This issue of IOP Conference Series: Earth and Environmental Science contains selected papers presented at the Padjadjaran Earth Dialogues: International Symposium on Geophysical Issues, PEDISGI. The meeting was held from June 8 to 10, 2015, at the Bale-Sawala of Universitas Padjadjaran in Jatinangor, Indonesia. The PEDISGI is a symposium to accommodate communication between researchers, in particular geophysicists and related scientists, and to enable sharing of knowledge and research findings concerning local and global geophysical issues. The symposium was attended by 126 participants and 64 contributors from Indonesian universities and the neighbouring countries in four categories, viz. Theoretical and Computational Geophysics, Environmental Geophysics, Geophysical Explorations, and Geophysical Instrumentations and Methods. The symposium was accompanied by a dialog, discussing a chosen topic regarding environmental and geological problems of relevance for the Indonesian archipelago and the surrounding regions. For this first event the topic was ''The formation of Bandung-Basin between myths and facts: Exemplary cultural, geological and geophysical study on the evolution of the earth surface'', presented by invited speakers and local experts. This activity was aimed at extending our knowledge on this particular subject, which may have global impact. This topic was augmented by theoretical background lectures on the earth's surface formation, presented by the invited speakers of the symposium. The meeting would not have been successful without the assistance of the local organizing committee. We want to specially thank Irwan A. Dharmawan for managing the programme, Anggie Susilawati and Mia U. Hasanah for the conference administration, and Dini Fitriani for financial management. We also thank the National Geographic Indonesia for its support via the Business to Business Collaboration Program. The conference photograph can be viewed in the PDF.

  18. NDIA 2018 IM and EM Technology Symposium: Innovative Insensitive Munition Solutions for Enhanced Warfighter Effectiveness

    Science.gov (United States)

    2018-04-26

    2018 IM & EM TECHNOLOGY SYMPOSIUM INNOVATIVE INSENSITIVE MUNITION SOLUTIONS FOR ENHANCED WARFIGHTER EFFECTIVENESS April 23 – 26, 2018 Doubletree by...IM & EM TECHNOLOGY SYMPOSIUM On behalf of the Insensitive Munitions and Energetic Materials Committee and our MSIAC partner, I would like to...welcome you to the 2018 Insensitive Munitions and Energetic Materials Technology Symposium. This international gathering of the top chemists, system

  19. International Symposium on Disarmament Education: A Report. Proceedings from a World Confederation of Organizations of the Teaching Profession and Japan Teachers Union Symposium (Hiroshima, Japan, October 25-29, 1982).

    Science.gov (United States)

    Japan Teachers Union, Tokyo.

    Proceedings from an international symposium devoted to the cause of disarmament education are presented. Representatives from international and national teacher organizations together with scholars and researchers from 35 countries and all continents attended. The symposium focused on the idea that teachers have a special responsibility to work…

  20. Symposium 1 of JENAM 2010

    CERN Document Server

    Molaro, Paolo; From Varying Couplings to Fundamental Physics

    2011-01-01

    Nature is characterized by a number of physical laws and fundamental dimensionless couplings. These determine the  properties of our physical universe, from the size of atoms, cells and mountains to the ultimate fate of the universe as a whole. Yet it is rather remarkable how little we know about them. The constancy of physical laws is one of the cornerstones of the scientific research method, but for fundamental couplings this is an assumption with no other justification  than a historical assumption. There is no 'theory of constants' describing their role in the underlying theories and how they relate to one another or how many  of them are truly fundamental.  Studying the behaviour of these quantities throughout the history of the universe is an effective way to probe fundamental physics. This explains why the ESA and ESO include varying fundamental constants among their key science drivers for the next generation of facilities. This symposium discussed the state-of-the-art in the field, as well as the...

  1. Proceedings of the symposium on frontier nuclear physics (FRONP99)

    International Nuclear Information System (INIS)

    Chiba, Satoshi

    2000-01-01

    The symposium on Frontier Nuclear Physics (FRONP99), organized by the Research Group for Hadron Science, Advanced Science Research Center, under close cooperation with the Research Center for Nuclear Physics, Osaka University and High Energy Accelerator Research Organization, was held at Tokai Research Establishment of JAERI on August 2 to 4, 1999. The symposium was devoted for discussions and presentations of research results in wide variety of fields such as hyper nuclear physics, lepton nuclear physics, quark nuclear physics, unstable nuclear physics, superheavy elements and heavy-ion physics. Three talks on the joint project between JAERI (Neutron Science Research Center) and KEK (JHF) were presented in a public session. Thirty three talks on these topics presented at the symposium aroused lively discussions among approximately 70 participants. This report contains 26 papers submitted from the lecturers. (author)

  2. Proinflammatory adipokine leptin mediates disinfection byproduct bromodichloromethane-induced early steatohepatitic injury in obesity

    International Nuclear Information System (INIS)

    Das, Suvarthi; Kumar, Ashutosh; Seth, Ratanesh Kumar; Tokar, Erik J.; Kadiiska, Maria B.; Waalkes, Michael P.; Mason, Ronald P.; Chatterjee, Saurabh

    2013-01-01

    Today's developed world faces a major public health challenge in the rise in the obese population and the increased incidence in fatty liver disease. There is a strong association among diet induced obesity, fatty liver disease and development of nonalcoholic steatohepatitis but the environmental link to disease progression remains unclear. Here we demonstrate that in obesity, early steatohepatitic lesions induced by the water disinfection byproduct bromodichloromethane are mediated by increased oxidative stress and leptin which act in synchrony to potentiate disease progression. Low acute exposure to bromodichloromethane (BDCM), in diet-induced obesity produced oxidative stress as shown by increased lipid peroxidation, protein free radical and nitrotyrosine formation and elevated leptin levels. Exposed obese mice showed histopathological signs of early steatohepatitic injury and necrosis. Spontaneous knockout mice for leptin or systemic leptin receptor knockout mice had significantly decreased oxidative stress and TNF-α levels. Co-incubation of leptin and BDCM caused Kupffer cell activation as shown by increased MCP-1 release and NADPH oxidase membrane assembly, a phenomenon that was decreased in Kupffer cells isolated from leptin receptor knockout mice. In obese mice that were BDCM-exposed, livers showed a significant increase in Kupffer cell activation marker CD68 and, increased necrosis as assessed by levels of isocitrate dehydrogenase, events that were decreased in the absence of leptin or its receptor. In conclusion, our results show that exposure to the disinfection byproduct BDCM in diet-induced obesity augments steatohepatitic injury by potentiating the effects of leptin on oxidative stress, Kupffer cell activation and cell death in the liver. - Highlights: ► BDCM acute exposure sensitizes liver to increased free radical stress in obesity. ► BDCM-induced higher leptin contributes to early steatohepatitic lesions. ► Increased leptin mediates protein

  3. Proinflammatory adipokine leptin mediates disinfection byproduct bromodichloromethane-induced early steatohepatitic injury in obesity

    Energy Technology Data Exchange (ETDEWEB)

    Das, Suvarthi [Environmental Health and Disease Laboratory, Department of Environmental Health Sciences, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208 (United States); Kumar, Ashutosh [Free Radical Metabolism Group, Laboratory of Toxicology and Pharmacology, Research Triangle Park, NC 27709 (United States); Seth, Ratanesh Kumar [Environmental Health and Disease Laboratory, Department of Environmental Health Sciences, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208 (United States); Tokar, Erik J. [Inorganic Toxicology Group, National Toxicology Program Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709 (United States); Kadiiska, Maria B. [Free Radical Metabolism Group, Laboratory of Toxicology and Pharmacology, Research Triangle Park, NC 27709 (United States); Waalkes, Michael P. [Inorganic Toxicology Group, National Toxicology Program Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709 (United States); Mason, Ronald P. [Free Radical Metabolism Group, Laboratory of Toxicology and Pharmacology, Research Triangle Park, NC 27709 (United States); Chatterjee, Saurabh, E-mail: schatt@mailbox.sc.edu [Environmental Health and Disease Laboratory, Department of Environmental Health Sciences, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208 (United States)

    2013-06-15

    Today's developed world faces a major public health challenge in the rise in the obese population and the increased incidence in fatty liver disease. There is a strong association among diet induced obesity, fatty liver disease and development of nonalcoholic steatohepatitis but the environmental link to disease progression remains unclear. Here we demonstrate that in obesity, early steatohepatitic lesions induced by the water disinfection byproduct bromodichloromethane are mediated by increased oxidative stress and leptin which act in synchrony to potentiate disease progression. Low acute exposure to bromodichloromethane (BDCM), in diet-induced obesity produced oxidative stress as shown by increased lipid peroxidation, protein free radical and nitrotyrosine formation and elevated leptin levels. Exposed obese mice showed histopathological signs of early steatohepatitic injury and necrosis. Spontaneous knockout mice for leptin or systemic leptin receptor knockout mice had significantly decreased oxidative stress and TNF-α levels. Co-incubation of leptin and BDCM caused Kupffer cell activation as shown by increased MCP-1 release and NADPH oxidase membrane assembly, a phenomenon that was decreased in Kupffer cells isolated from leptin receptor knockout mice. In obese mice that were BDCM-exposed, livers showed a significant increase in Kupffer cell activation marker CD68 and, increased necrosis as assessed by levels of isocitrate dehydrogenase, events that were decreased in the absence of leptin or its receptor. In conclusion, our results show that exposure to the disinfection byproduct BDCM in diet-induced obesity augments steatohepatitic injury by potentiating the effects of leptin on oxidative stress, Kupffer cell activation and cell death in the liver. - Highlights: ► BDCM acute exposure sensitizes liver to increased free radical stress in obesity. ► BDCM-induced higher leptin contributes to early steatohepatitic lesions. ► Increased leptin mediates

  4. Ligand activation of peroxisome proliferator-activated receptor-β/δ suppresses liver tumorigenesis in hepatitis B transgenic mice

    International Nuclear Information System (INIS)

    Balandaram, Gayathri; Kramer, Lance R.; Kang, Boo-Hyon; Murray, Iain A.; Perdew, Gary H.; Gonzalez, Frank J.; Peters, Jeffrey M.

    2016-01-01

    Highlights: • The role of PPARβ/δ in HBV-induced liver cancer was examined. • PPARβ/δ inhibits steatosis, inflammation, tumor multiplicity and promotes apoptosis. • Kupffer cell PPARβ/δ mediates these effects independent of DNA binding. - Abstract: Peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) inhibits steatosis and inflammation, known risk factors for liver cancer. In this study, the effect of ligand activation of PPARβ/δ in modulating liver tumorigenesis in transgenic hepatitis B virus (HBV) mice was examined. Activation of PPARβ/δ in HBV mice reduced steatosis, the average number of liver foci, and tumor multiplicity. Reduced expression of hepatic CYCLIN D1 and c-MYC, tumor necrosis factor alpha (Tnfa) mRNA, serum levels of alanine aminotransaminase, and an increase in apoptotic signaling was also observed following ligand activation of PPARβ/δ in HBV mice compared to controls. Inhibition of Tnfa mRNA expression was not observed in wild-type hepatocytes. Ligand activation of PPARβ/δ inhibited lipopolysaccharide (LPS)-induced mRNA expression of Tnfa in wild-type, but not in Pparβ/δ-null Kupffer cells. Interestingly, LPS-induced expression of Tnfa mRNA was also inhibited in Kupffer cells from a transgenic mouse line that expressed a DNA binding mutant form of PPARβ/δ compared to controls. Combined, these results suggest that ligand activation of PPARβ/δ attenuates hepatic tumorigenesis in HBV transgenic mice by inhibiting steatosis and cell proliferation, enhancing hepatocyte apoptosis, and modulating anti-inflammatory activity in Kupffer cells.

  5. 5th International Symposium on Experimental Mechanics (5-ISEM) and 9th Symposium on Optics in Industry

    CERN Document Server

    Furlong, Cosme; Barrientos, Bernardino; Pryputniewicz, Ryszard

    2017-01-01

    This book contains papers of the 5th International Symposium on Experimental Mechanics (5-ISEM) and the 9th Symposium on Optics in Industry (9-SOI), whose general theme is Emerging Challenges for Experimental Mechanics in Energy and Environmental Applications. These symposia are organized by Centro de Investigaciones en Optica (CIO) and Mexican Academy for Optics (AMO), under the sponsorship of the Society of Experimental Mechanics (SEM) and other national and international Organizations; Symposia are interdisciplinary forums for engineers, technicians, researchers and managers involved in all fields of Optics, Opto-mechatronics, Mechanics and Mechanical Engineering. · Addresses a broad readership including graduate and postgraduate students, researchers, and engineers working in experimental mechanics and in the application of optical methods · Covers a broad spectrum of topics highlighting the use of optical methods in experimental mechanics, energy, and in the environment.

  6. Ninth International Symposium on Recent Advances in Environmental Health Research

    Directory of Open Access Journals (Sweden)

    Paul B. Tchounwou

    2014-01-01

    Full Text Available This special issue of International Journal of Environmental Research and Public Health is dedicated to the publication of selected papers presented at the Eighth International Symposium on Recent Advances in Environmental Health Research. The Symposium was organized by Jackson State University (JSU from 16–19 September, 2012 at the Marriott Hotel in Jackson, Mississippi, USA. It was built upon the overwhelming success of seven previous symposia hosted by JSU.

  7. Symposium proceedings: environmental aspects of fuel conversion technology, IV (April 1979, Hollywood, FL)

    Energy Technology Data Exchange (ETDEWEB)

    Ayer, F.A.; Jones, N.S. (comps.)

    1979-09-01

    The proceedings document presentations made at the symposium on Environmental Aspects of Fuel Conversion Technology are presented. The symposium acted as a colloquium for discussion of environmentally related information on coal gasification and liquefaction. The program included sessions on program approach, environmental assessment, and control technology development. Process developers, process users, research scientists and state and federal government officials participated in this symposium, the fourth to be conducted by IERL-RTP on the subject since 1974. Separate abstracts have been prepared of individual presentations for inclusion in the Energy Data Base.

  8. 4. Danish symposium in analytical chemistry

    International Nuclear Information System (INIS)

    1996-01-01

    At the 4th Danish Symposium of Analytical Chemistry 11 lectures and 32 posters were presented during two session days on the 20 and 21 August 1996. Various analytical techniques were discussed for foodstuff, pesticide, pharmaceutical, industrial and other analyses. (EG)

  9. The Wharton Symposium: Facing the Issues.

    Science.gov (United States)

    Sullivan, David M.

    1982-01-01

    A public relations practitioner reports enthusiastically on his return to the campus for an "intellectually-broadening" public relations symposium. He summarizes critical social and economic issues addressed by distinguished scholars and experienced practitioners. For journal availability, see CS 705 902. (PD)

  10. PREFACE: Fullerene Nano Materials (Symposium of IUMRS-ICA2008)

    Science.gov (United States)

    Miyazawa, Kun'ichi; Fujita, Daisuke; Wakahara, Takatsugu; Kizuka, Tokushi; Matsuishi, Kiyoto; Ochiai, Yuichi; Tachibana, Masaru; Ogata, Hironori; Mashino, Tadahiko; Kumashiro, Ryotaro; Oikawa, Hidetoshi

    2009-07-01

    This volume contains peer-reviewed invited and contributed papers that were presented in Symposium N 'Fullerene Nano Materials' at the IUMRS International Conference in Asia 2008 (IUMRS-ICA 2008), which was held on 9-13 December 2008, at Nagoya Congress Center, Nagoya, Japan. Over twenty years have passed since the discovery of C60 in 1985. The discovery of superconductivity of C60 in 1991 suggested infinite possibilities for fullerenes. On the other hand, a new field of nanocarbon has been developed recently, based on novel functions of the low-dimensional fullerene nanomaterials that include fullerene nanowhiskers, fullerene nanotubes, fullerene nanosheets, chemically modified fullerenes, endohedral fullerenes, thin films of fullerenes and so forth. Electrical, electrochemical, optical, thermal, mechanical and various other properties of fullerene nanomaterials have been investigated and their novel and anomalous nature has been reported. Biological properties of fullerene nanomaterials also have been investigated both in medical applications and toxicity aspects. The recent research developments of fullerene nanomaterials cover a variety of categories owing to their functional diversity. This symposium aimed to review the progress in the state-of-the-art technology based on fullerenes and to offer the forum for active interdisciplinary discussions. 24 oral papers containing 8 invited papers and 22 poster papers were presented at the two-day symposium. Topics on the social acceptance of nanomaterials including fullerene were presented on the first day of the symposium. Biological impacts of nanomaterials and the importance of standardization of nanomaterials characterization were also shown. On the second day, the synthesis, properties, functions and applications of various fullerene nanomaterials were shown in both the oral and poster presentations. We are grateful to all invited speakers and many participants for valuable contributions and active discussions

  11. Roundtable discussion on the Third Global Symposium on Health Systems Research

    DEFF Research Database (Denmark)

    Lazarus, Jeffrey V; Balabanova, Dina; Safreed-Harmon, Kelly

    2015-01-01

    Health systems experts from around the world discuss why they were meeting at the Third Global Symposium on Health Systems Research while people were dying of Ebola in West Africa.......Health systems experts from around the world discuss why they were meeting at the Third Global Symposium on Health Systems Research while people were dying of Ebola in West Africa....

  12. Proceedings of 8th Symposium of the Croatian Radiation Protection Association

    Energy Technology Data Exchange (ETDEWEB)

    Krajcar Bronic, I; Kopjar, N; Milic, M; Branica, G

    2011-07-01

    The 8th symposium of the Croatian Radiation Protection Association discussed the following topics: general topics; radiation dosimetry and instrumentation; public exposure; biological effects of radiation; radiation protection in medicine; radioecology and non-ionizing radiation. For each subject many investigations, experiments, examples and results are presented. International character of this symposium shows importance of these topics not only in region but world wide.

  13. Proceedings of 8th Symposium of the Croatian Radiation Protection Association

    International Nuclear Information System (INIS)

    Krajcar Bronic, I.; Kopjar, N.; Milic, M.; Branica, G.

    2011-01-01

    The 8th symposium of the Croatian Radiation Protection Association discussed the following topics: general topics; radiation dosimetry and instrumentation; public exposure; biological effects of radiation; radiation protection in medicine; radioecology and non-ionizing radiation. For each subject many investigations, experiments, examples and results are presented. International character of this symposium shows importance of these topics not only in region but world wide.

  14. Proceedings of 9th Symposium of the Croatian Radiation Protection Association

    International Nuclear Information System (INIS)

    Knezevic, Z.; Krajcar Bronic, I.; Majer, M.

    2013-01-01

    The 9th symposium of the Croatian Radiation Protection Association discussed the following topics: general topics; radiation dosimetry; public exposure; biological effects of radiation; radiation protection in medicine; radioecology and instrumentation and measuring techniques. For each subject many investigations, experiments, examples and results are presented. International character of this symposium shows importance of these topics not only in region but world wide.

  15. Proceedings of the 1994 nuclear simulation symposium

    Energy Technology Data Exchange (ETDEWEB)

    Laughton, P J [ed.; Atomic Energy of Canada Ltd., Chalk River, ON (Canada). Chalk River Nuclear Labs.

    1994-12-31

    This symposium on nuclear simulation included sessions on reactor physics, on thermalhydraulics, and on fuel and fuel channels of CANDU type reactors. The individual papers have all been abstracted separately.

  16. Indian symposium reviews tsunami response

    Directory of Open Access Journals (Sweden)

    Paula Banerjee

    2005-07-01

    Full Text Available A symposium of academics and human rights activists organised by the Calcutta Research Group assessed the extent to which relief and rehabilitation initiatives in Tamil Nadu and the Andaman and Nicobar islands have recognised the rights of those affected to receive aid without discrimination based on caste, religion or gender.

  17. MEMORIAL SYMPOSIUM:
    Willi Jentschke

    CERN Multimedia

    CERN. Geneva

    2002-01-01

    - Welcome by L. Maiani - Message from DESY by E. Lohrmann - Willi Jentschke by H. Schopper - The Neutral Currents by M. Veltman and D. Perkins - The ISR in Jentschke's time by K. Johnsen - Some recollections of Jentschke by K. WinterNote: Participants are cordially invited to drinks at 17h.30 following the symposium

  18. 12. Kassel symposium of power system engineering - control technology for decentral power supply systems. Proceedings; Zwoelftes Kasseler Symposium Energie-Systemtechnik - Regelungstechnik fuer dezentrale Energiesysteme. Tagungsband

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    The 12. Kassel symposium of power system engineering focused on control technology for decentral power generation systems. It addressed experts of mechanical engineering, electrical engineering, control engineering and related fields. The symposium was to provide a picture of the state of the art of selected control systems and also to illustrate the immportance of control technology for these systems. Most of the papers used the example of large-capacity wind power systems, where the interdependence of mechanical and electrical engineering and the importance of control technology are particularly clear. The selected illustrate the interdisciplinary character of this engineering discipline, which is also the element that makes it so very interesting. The Kassel symposium therefore addressed not only experts but also students of these disciplines who want to find out more about the theory and practice of renewable power systems. (orig.)

  19. Chemical and Thermodynamic Properties at High Temperatures: A Symposium

    Science.gov (United States)

    Walker, Raymond F.

    1961-01-01

    This book contains the program and all available abstracts of the 90' invited and contributed papers to be presented at the TUPAC Symposium on Chemical and Thermodynamic Properties at High Temperatures. The Symposium will be held in conjunction with the XVIIIth IUPAC Congress, Montreal, August 6 - 12, 1961. It has been organized, by the Subcommissions on Condensed States and on Gaseous States of the Commission on High Temperatures and Refractories and by the Subcommission on Experimental Thermodynamics of the Commission on Chemical Thermodynamics, acting in conjunction with the Organizing Committee of the IUPAC Congress. All inquiries concerning participation In the Symposium should be directed to: Secretary, XVIIIth International Congress of Pure and Applied Chemistry, National Research Council, Ottawa, 'Canada. Owing to the limited time and facilities available for the preparation and printing of the book, it has not been possible to refer the proofs of the abstracts to the authors for checking. Furthermore, it has not been possible to subject the manuscripts to a very thorough editorial examination. Some obvious errors in the manuscripts have been corrected; other errors undoubtedly have been introduced. Figures have been redrawn only when such a step was essential for reproduction purposes. Sincere apologies are offered to authors and readers for any errors which remain; however, in the circumstances neither the IUPAC Commissions who organized the Symposium, nor the U. S. Government Agencies who assisted in the preparation of this book can accept responsibility for the errors.

  20. Proceedings of the symposium on leukemia clustering

    Energy Technology Data Exchange (ETDEWEB)

    Elaguppillai, V [Atomic Energy Control Board, Ottawa, ON (Canada); Goyette, J P [Atomic Energy Control Board, Ottawa, ON (Canada). Advisory Committee on Radiological Protection; Hill, G; Krewski, D [Department of National Health and Welfare, Ottawa, ON (Canada); Osborne, R V [Atomic Energy of Canada Ltd., Chalk River, ON (Canada). Chalk River Nuclear Labs.

    1992-07-01

    Clusters of leukemia in populations living in specific locations in various countries have been examined by scientific and medical experts for many years. In general, the reason for the existence of these clusters is unknown. The recent discovery of a small cluster of leukemias among children who were born in the vicinity of a nuclear fuel reprocessing facility in England has stimulated wide interest in the possible occurrence of clusters of leukemia around nuclear facilities. The purpose of this symposium was to present scientific evidence concerning the existence of leukemia clusters in the population, to discuss possible causes for these clusters and to suggest directions for future research. Distinguished speakers from Canada, the United Kingdom, Germany, Italy and the U.S.A. participated in this symposium. (author).

  1. Proceedings of the symposium on leukemia clustering

    International Nuclear Information System (INIS)

    Elaguppillai, V.; Goyette, J.P.; Osborne, R.V.

    1992-07-01

    Clusters of leukemia in populations living in specific locations in various countries have been examined by scientific and medical experts for many years. In general, the reason for the existence of these clusters is unknown. The recent discovery of a small cluster of leukemias among children who were born in the vicinity of a nuclear fuel reprocessing facility in England has stimulated wide interest in the possible occurrence of clusters of leukemia around nuclear facilities. The purpose of this symposium was to present scientific evidence concerning the existence of leukemia clusters in the population, to discuss possible causes for these clusters and to suggest directions for future research. Distinguished speakers from Canada, the United Kingdom, Germany, Italy and the U.S.A. participated in this symposium. (author)

  2. CUBE (Computer Use By Engineers) symposium abstracts

    International Nuclear Information System (INIS)

    Ruminer, J.J.

    1978-07-01

    This report presents the abstracts for the CUBE (Computer Use by Engineers) Symposium, October 4, through 6, 1978. Contributors are from Lawrence Livermore Laboratory, Los Alamos Scientific Laboratory, and Sandia Laboratories

  3. SYMPOSIUM ON TURBULENCE AND COMBUSTION - SPECIAL SYMPOSIUM TO BRING TOGETHER TOP RESEARCHERS IN THE FIELDS OF FLUID TURBULENCE AND COMBUSTION TO PROMOTE ADVANCES IN TURBULENT, REACTING FLOWS

    Energy Technology Data Exchange (ETDEWEB)

    Caughey, David

    2010-10-08

    A Symposium on Turbulence and Combustion was held at Cornell University on August 3-4, 2009. The overall goal of the Symposium was to promote future advances in the study of turbulence and combustion, through an unique forum intended to foster interactions between leading members of these two research communities. The Symposium program consisted of twelve invited lectures given by world-class experts in these fields, two poster sessions consisting of nearly 50 presentations, an open forum, and other informal activities designed to foster discussion. Topics covered in the lectures included turbulent dispersion, wall-bounded flows, mixing, finite-rate chemistry, and others, using experiment, modeling, and computations, and included perspectives from an international community of leading researchers from academia, national laboratories, and industry.

  4. Summary of 2 nd Nordic symposium on digital pathology

    Directory of Open Access Journals (Sweden)

    Claes Lundström

    2015-01-01

    Full Text Available Techniques for digital pathology are envisioned to provide great benefits in clinical practice, but experiences also show that solutions must be carefully crafted. The Nordic countries are far along the path toward the use of whole-slide imaging in clinical routine. The Nordic Symposium on Digital Pathology (NDP was created to promote knowledge exchange in this area, between stakeholders in health care, industry, and academia. This article is a summary of the NDP 2014 symposium, including conclusions from a workshop on clinical adoption of digital pathology among the 144 attendees.

  5. Summary of 2nd Nordic symposium on digital pathology

    Science.gov (United States)

    Lundström, Claes; Thorstenson, Sten; Waltersson, Marie; Persson, Anders; Treanor, Darren

    2015-01-01

    Techniques for digital pathology are envisioned to provide great benefits in clinical practice, but experiences also show that solutions must be carefully crafted. The Nordic countries are far along the path toward the use of whole-slide imaging in clinical routine. The Nordic Symposium on Digital Pathology (NDP) was created to promote knowledge exchange in this area, between stakeholders in health care, industry, and academia. This article is a summary of the NDP 2014 symposium, including conclusions from a workshop on clinical adoption of digital pathology among the 144 attendees. PMID:25774316

  6. Summary of 2(nd) Nordic symposium on digital pathology.

    Science.gov (United States)

    Lundström, Claes; Thorstenson, Sten; Waltersson, Marie; Persson, Anders; Treanor, Darren

    2015-01-01

    Techniques for digital pathology are envisioned to provide great benefits in clinical practice, but experiences also show that solutions must be carefully crafted. The Nordic countries are far along the path toward the use of whole-slide imaging in clinical routine. The Nordic Symposium on Digital Pathology (NDP) was created to promote knowledge exchange in this area, between stakeholders in health care, industry, and academia. This article is a summary of the NDP 2014 symposium, including conclusions from a workshop on clinical adoption of digital pathology among the 144 attendees.

  7. Proceedings of the twelfth Symposium of Atomic Energy Research

    International Nuclear Information System (INIS)

    Vidovszky, Istvan

    2002-11-01

    The present volume contains 45 papers, presented on the twelfth Symposium of Atomic Energy Research, held in Sunny Beach, Bulgaria, 22-28 September 2002. The papers are presented in their original form, i. e. no corrections or modifications were carried out. The content of this volume is divided into thematic groups: Core Monitoring, Surveillance and Testing, Safety Issues, Core Operation and Fuel Management, Spectral and Core Calculation Methods, Spent Fuel Transmutations and Decommissioning, Neutron Kinetics and reactor Dynamics Methods, Poster Session - according to the presentation sequence on the Symposium

  8. Proceedings of the fifteenth Symposium of Atomic Energy Research

    International Nuclear Information System (INIS)

    Vidovszky, I.

    2005-11-01

    The present volume contains 59 papers, presented on the fifteenth Symposium of Atomic Energy Research, held in Znojmo, Czech Republic, 3-7 October 2005. The papers are presented in their original form, i. e. no corrections or modifications were carried out. The content of this volume is divided into thematic groups: Spectral and Core Calculation Methods, Core Design, Operation and Fuel Management, Core Monitoring, Surveillance and Testing, Neutron Kinetics and Reactor Dynamics Methods, Criticality Safety, Spent Fuel, and CFD Codes Application - according to the presentation sequence on the Symposium

  9. Proceedings of the eleventh Symposium of Atomic Energy Research

    International Nuclear Information System (INIS)

    Vidovszky, Istvan

    2001-12-01

    The present volume contains 57 papers, presented on the eleventh Symposium of Atomic Energy Research, held in Csopak, Hungary, 24-28 September 2001. The papers are presented in their original form, i. e. no corrections or modifications were carried out. The content of this volume is divided into thematic groups: Improvement of Neutron Physical Codes and Methods, Reactor Kinetics and Dynamics, Thermal-Hydraulics, Spent Fuel - Criticality Radiation, Fuel Behaviour, Spent Fuel Transmutation, Evaluation of Reactor Physical Measurements, Core Design-Core Calculations-according to the presentation sequence on the Symposium (Author)

  10. Proceedings of the thirteenth Symposium of Atomic Energy Research

    International Nuclear Information System (INIS)

    Vidovszky, Istvan

    2003-11-01

    The present volume contains 58 papers, presented on the thirteenth Symposium of Atomic Energy Research, held in Dresden, Germany, 22-26 September 2003. The papers are presented in their original form, i. e. no corrections or modifications were carried out. The content of this volume is divided into thematic groups: Core Monitoring, Surveillance and Testing, Safety Issues, Spectral and Core Calculation Methods, Core Operation and Fuel Management, Spent Fuel Transmutations and Decommissioning, Neutron Kinetics and reactor Dynamics Methods, Poster Session - according to the presentation sequence on the Symposium

  11. Proceedings of the first symposium on Monte Carlo simulation

    International Nuclear Information System (INIS)

    2001-01-01

    The first symposium on Monte Carlo simulation was held at Mitsubishi Research Institute, Otemachi, Tokyo, on 10th and 11st of September, 1998. This symposium was organized by Nuclear Code Research Committee at Japan Atomic Energy Research Institute. In the sessions, were presented orally 21 papers on code development, parallel calculation, reactor physics, burn-up, criticality, shielding safety, dose evaluation, nuclear fusion reactor, thermonuclear fusion plasma, nuclear transmutation, electromagnetic cascade, fuel cycle facility. Those presented papers are compiled in this proceedings. The 21 of the presented papers are indexed individually. (J.P.N.)

  12. Symposium Summary

    Science.gov (United States)

    Levesque, Emily M.

    2017-11-01

    This proceeding summarizes the highlights of IAU 329, ``The Lives and Death-Throes of Massive Stars'', held in Auckland, NZ from 28 Nov - 2 Dec. I consider the progress that has been made in the field over the course of these ``beach symposia'', outline the overall content of the conference, and discuss how the current subfields in massive stellar astrophysics have evolved in recent years. I summarize some of the new results and innovative approaches that were presented during the symposium, and conclude with a discussion of how current and future resources in astronomy can serve as valuable tools for studying massive stars in the coming years.

  13. Pseudoislets as primary islet replacements for research: report on a symposium at King's College London, London UK.

    Science.gov (United States)

    Persaud, Shanta J; Arden, Catherine; Bergsten, Peter; Bone, Adrian J; Brown, James; Dunmore, Simon; Harrison, Moira; Hauge-Evans, Astrid; Kelly, Catriona; King, Aileen; Maffucci, Tania; Marriott, Claire E; McClenaghan, Neville; Morgan, Noel G; Reers, Christina; Russell, Mark A; Turner, Mark D; Willoughby, Emma; Younis, Mustafa Y G; Zhi, Z L; Jones, Peter M

    2010-01-01

    Laboratory-based research aimed at understanding processes regulating insulin secretion and mechanisms underlying β-cell dysfunction and loss in diabetes often makes use of rodents, as these processes are in many respects similar between rats/mice and humans. Indeed, a rough calculation suggests that islets have been isolated from as many as 150,000 rodents to generate the data contained within papers published in 2009 and the first four months of 2010. Rodent use for islet isolation has been mitigated, to a certain extent, by the availability of a variety of insulin-secreting cell lines that are used by researchers world-wide. However, when maintained as monolayers the cell lines do not replicate the robust, sustained secretory responses of primary islets which limits their usefulness as islet surrogates. On the other hand, there have been several reports that configuration of MIN6 β-cells, derived from a mouse insulinoma, as three-dimensional cell clusters termed ‘pseudoislets’ largely recapitulates the function of primary islet β-cells. The Diabetes Research Group at King’s College London has been using the MIN6 pseudoislet model for over a decade and they hosted a symposium on “Pseudoislets as primary islet replacements for research”, which was funded by the UK National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs), in London on 15th and 16th April 2010. This small, focused meeting was conceived as an opportunity to consolidate information on experiences of working with pseudoislets between different UK labs, and to introduce the theory and practice of pseudoislet culture to laboratories working with islets and/or β-cell lines but who do not currently use pseudoislets. This short review summarizes the background to the development of the cell line-derived pseudoislet model, the key messages arising from the symposium and emerging themes for future pseudoislet research.

  14. Proceedings of the 1999 symposium on nuclear data

    Energy Technology Data Exchange (ETDEWEB)

    Yamano, Naoki; Fukahori, Tokio [eds.

    2000-03-01

    The 1999 Symposium on Nuclear Data was held at Tokai Research Establishment, Japan Atomic Energy Research Institute (JAERI), on 18th and 19th of November 1999. Japanese Nuclear Data Committee and Nuclear Data Center, JAERI organized this symposium. In the oral sessions, presented papers were on keynote address, nuclear data measurement for long-lived RI and in medium energy region, status of JENDL, international session and other topics. In the poster session, presented papers were concerning experiments, evaluations, benchmark tests and on-line database on nuclear data. Those presented papers are compiled in the proceedings. The 64 of the presented papers are indexed individually. (J.P.N.)

  15. Symposium “Mapping the Galaxy and Nearby Galaxies”

    CERN Document Server

    Wada, Keiichi; ASTROPHYSICS AND SPACE SCIENCE PROCEEDINGS

    2008-01-01

    This is a proceedings book of the symposium "Mapping the Galaxy and Nearby Galaxies" held on Ishigaki Island, Okinawa, Japan, on June 25 – 30, 2006. The symposium focused on mapping the interstellar media and other components in galaxies. Latest results of the following main topics are presented in the volume: Our Galaxy -- mass distribution, local ISM, supermassive black holes and their environments Central part of nearby galaxies -- ISM around starbursts, fueling mechanisms Nearby Galaxies -- molecular gas and star formation, gas dynamics Galactic environment and evolution -- formation of our Galaxy, origin of supermassive black holes The nature of the Dark Matter component -- effects on the internal structures of galaxies

  16. The Physics of Beams: The Andrew Sessler Symposium

    International Nuclear Information System (INIS)

    Barletta, W.A.

    1996-01-01

    These proceedings represent papers presented at the Andrew Sessler Symposium held at the Lawrence Berkeley National Laboratory in honor of Andrew Sessler close-quote s over forty years of major scientific contributions to accelerator and beam physics as well as in celebration of his 65th birthday. The symposium was sponsored by the United States Department of Energy. The topics discussed include linear colliders, past history and future speculations, ELOISATRON at 100 TeV beam, manipulating charged particle beams by means of plasma and collective instabilities in accelerator and storage rings. There were 10 papers presented and 8 have been abstracted for the Energy Science and Technology database

  17. Proceedings of the 1998 symposium on nuclear data

    Energy Technology Data Exchange (ETDEWEB)

    Yoshida, Tadashi; Fukahori, Tokio [eds.] [Japanese Nuclear Data Committee, Tokai, Ibaraki (Japan)

    1999-03-01

    The 1998 Symposium on Nuclear Data was held at Tokai Research Establishment, Japan Atomic Energy Research Institute (JAERI), on 19th and 20th of November 1998. Japanese Nuclear Data Committee and Nuclear Data Center, JAERI organized this symposium. In the oral sessions, presented papers were on accelerator facilities, astrophysics and nuclear data, international session, radiation damage study and nuclear data, and integral test of nuclear data. In the poster session, presented papers were concerning experiments, evaluations, benchmark tests and on-line database on nuclear data. Those presented papers are compiled in this proceedings. The 50 of the presented papers are indexed individually. (J.P.N.)

  18. Liver scanning using indium-113m at the University Teaching Hospital, Lusaka, Zambia

    Energy Technology Data Exchange (ETDEWEB)

    Mulaisho, C [Nuclear Medicine Unit, Department of Medicine, University of Zambia, Lusaka, Zambia; Mumba, K N [Radio-isotope Research Unit, National Council for Scientific Research, Lusaka, Zambia

    1981-11-21

    Liver scanning using the radio-isotope indium-113m, can now be routinely perfomed at the University Teaching Hospital, Lusaka, Zambia. The dose used is 1 - 4 mCi. Liver scans have been performed on 48 subjects, including 10 healthy individuals 16 patients with histologically proven hepatocellular carcinoma, 11 with clinical and laboratory evidence of portal hypertension and 11 with miscellaneous illnesses. Seven representative scans are illustrated. The procedure is easy, and gives a fairly accurate functional estimate of Kupffer cell mass. In hepatoma the scan may be either larger than or smaller than normal and reflects more accurately the residual function of the Kupffer cells. In cirrhosis of the liver with portal hypertention, residual Kupffer cell mass is small. Consequently, most of the indium-113m is taken up by the splenic reticulo-endothelial system, resulting in a large spleen scan. This technique, although fraught with major limitations, is a useful additional diagnostic tool in the management of chronic liver disease.

  19. Symposium on international safeguards: Addressing verification challenges. Book of extended synopses

    International Nuclear Information System (INIS)

    2006-01-01

    A safeguards symposium has traditionally been organized by the Safeguards Department approximately every four years. The 2006 symposium addresses challenges to IAEA safeguards that have emerged or grown more serious since 2001. The increase in size and flexibility of uranium enrichment plants, for instance, and the spread of enrichment technology to a wider circle of States, pose challenges to traditional safeguards approaches. The procurement and supply networks discovered in 2004, dealing in sensitive nuclear technology and information, have serious implications for the future effectiveness of IAEA safeguards. The symposium will provide an opportunity for the IAEA and Member States to discuss options for dealing constructively with trade in sensitive nuclear technology. Reflecting developments since 2001, the 2006 symposium will focus on current challenges to the safeguards system, improving collection and analysis of safeguards information (analysis, processing tools, satellite imagery), advances in safeguards techniques and technology (future technology, neutron techniques, spent fuel verification, reprocessing, environmental sampling, containment and surveillance), further strengthening safeguards practices and approaches (safeguards approaches, integrated safeguards, R/SSAC, destructive analysis, non-destructive analysis, enrichment, reprocessing, spent fuel transfer) and future challenges. This publication contains 183 extended synopses, each of them was indexed separately

  20. Symposium on international safeguards: Addressing verification challenges. Book of extended synopses

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    A safeguards symposium has traditionally been organized by the Safeguards Department approximately every four years. The 2006 symposium addresses challenges to IAEA safeguards that have emerged or grown more serious since 2001. The increase in size and flexibility of uranium enrichment plants, for instance, and the spread of enrichment technology to a wider circle of States, pose challenges to traditional safeguards approaches. The procurement and supply networks discovered in 2004, dealing in sensitive nuclear technology and information, have serious implications for the future effectiveness of IAEA safeguards. The symposium will provide an opportunity for the IAEA and Member States to discuss options for dealing constructively with trade in sensitive nuclear technology. Reflecting developments since 2001, the 2006 symposium will focus on current challenges to the safeguards system, improving collection and analysis of safeguards information (analysis, processing tools, satellite imagery), advances in safeguards techniques and technology (future technology, neutron techniques, spent fuel verification, reprocessing, environmental sampling, containment and surveillance), further strengthening safeguards practices and approaches (safeguards approaches, integrated safeguards, R/SSAC, destructive analysis, non-destructive analysis, enrichment, reprocessing, spent fuel transfer) and future challenges. This publication contains 183 extended synopses, each of them was indexed separately.

  1. 6th Asian Physics Symposium

    International Nuclear Information System (INIS)

    2016-01-01

    Preface: The 6th Asian Physics Symposium 2015 (APS 2015) The 6th Asian Physics Symposium 2015 (APS 2015) is organized by the Physics Department, Faculty of Mathematics and Natural Sciences, Bandung Institute of Technology, in collaboration with HFI (Indonesian Physical Society), PAPSI (Physics and Applied Physics Society of Indonesia), HANI (Indonesian Nuclear Scientist Society), HRMI (Indonesian Material Research Society), HAGI (Indonesian Geophysicist Society) - West Java Chapter, and HFMBI (Indonesian Medical Physicist and Biophysicist Society). APS 2015 is aimed at providing a forum of scientific communication and interaction among distinguished scientists working in physics and its related fields. In this scientific event the latest research will be presented, and state-of-the-art developments in the field discussed, to help to guide our future research directions. It is also designed to offer the opportunity for young Indonesian scientists and students to make direct contacts with well-known scientists abroad and thereby foster the existing research collaborations and extend international research networking for the future. The scope of research presented and discussed in this symposium covers theoretical high energy physics, materials sciences and technology, biophysics and medical physics, nuclear science and engineering, earth and planetary sciences, computational physics, instrumentation and measurement, physics education, and interdisciplinary physics. The program of APS 2016 features 6 invited talks and 208 contributed oral presentations, which come from 7 different countries: Japan, South Korea, Singapore, Malaysia, Iraq, Ethiopia, and Indonesia. All papers have been reviewed after they are presented in this event. Selected papers are published in this Institute of Physics (IoP) Conference Series. Finally, I would like to express my sincere appreciation to all of authors for their valuable contributions and also to the members of the committee for

  2. The ninth international veterinary immunology symposium

    Science.gov (United States)

    This Introduction to the special issue of Veterinary Immunology and Immunopathology summarizes the Proceedings of the 9th International Veterinary Immunology Symposium (9th IVIS) held August, 2010, in Tokyo, Japan. Over 340 delegates from 30 countries discussed research progress analyzing the immune...

  3. Abstracts: 2nd interventional MRI symposium

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1997-09-01

    Main topics of the 2nd interventional MRI symposium were: MR compatibility and pulse sequences; MR thermometry, biopsy, musculoskeletal system; laser-induced interstitial thermotherapy, radiofrequency ablations; intraoperative MR; vascular applications, breast, endoscopy; focused ultrasound, cryotherapy, perspectives; poster session with 34 posters described. (AJ)

  4. Abstracts: 2nd interventional MRI symposium

    International Nuclear Information System (INIS)

    Anon.

    1997-01-01

    Main topics of the 2nd interventional MRI symposium were: MR compatibility and pulse sequences; MR thermometry, biopsy, musculoskeletal system; laser-induced interstitial thermotherapy, radiofrequency ablations; intraoperative MR; vascular applications, breast, endoscopy; focused ultrasound, cryotherapy, perspectives; poster session with 34 posters described. (AJ)

  5. 11. European cosmic ray symposium

    International Nuclear Information System (INIS)

    1989-03-01

    The biannual Symposium includes all aspects of cosmic ray research. The scientific programme was organized under three main headings: Cosmic rays in the heliosphere, Cosmic rays in the interstellar and extragalactic space, Properties of high-energy interactions as studied by cosmic rays. Seven invited talks were indexed seprately for the INIS database. (R.P.)

  6. Quality assurance and demolition: 2008 symposium

    International Nuclear Information System (INIS)

    Schartmann, F.; Thierfeldt, S.

    2008-01-01

    The 'Quality Assurance and Demolition Symposium, which has become a tradition established jointly by Applus RTD Deutschland GmbH (formerly compra GmbH) and Brenk Systemplanung GmbH, Aachen, was held also in 2008 with the focus on quality assurance and the demolition of nuclear facilities. The conference began with a series of lectures on knowledge and document management in general, and the use of document management systems in the nuclear field in particular. The evening lecture was presented by Axel Weis (Karlsruhe Research Center) on 'Competence Preservation in Nuclear Technology'. The 24 technical papers presented on the next 2 days of the symposium dealt with non-destructive materials testing and with special problems of radiation protection, demolition, and waste management. In 2009, the meeting will cover similar main topics and will again be held in an interesting environment, perhaps in combination with a tour of a demolition project. (orig.)

  7. 2016 International Symposium on Experimental Robotics

    CERN Document Server

    Nakamura, Yoshihiko; Khatib, Oussama; Venture, Gentiane

    2017-01-01

    Experimental Robotics XV is the collection of papers presented at the International Symposium on Experimental Robotics, Roppongi, Tokyo, Japan on October 3-6, 2016. 73 scientific papers were selected and presented after peer review. The papers span a broad range of sub-fields in robotics including aerial robots, mobile robots, actuation, grasping, manipulation, planning and control and human-robot interaction, but shared cutting-edge approaches and paradigms to experimental robotics. The readers will find a breadth of new directions of experimental robotics. The International Symposium on Experimental Robotics is a series of bi-annual symposia sponsored by the International Foundation of Robotics Research, whose goal is to provide a forum dedicated to experimental robotics research. Robotics has been widening its scientific scope, deepening its methodologies and expanding its applications. However, the significance of experiments remains and will remain at the center of the discipline. The ISER gatherings are...

  8. DOE Grant to organize "International Symposium on Opportunities in Underground Physics", Asilomar, CA, May 24-27, 2013

    Energy Technology Data Exchange (ETDEWEB)

    Babu, Kaladi S. [Oklahoma State Univ., Stillwater, OK (United States)

    2015-03-16

    The International Symposium in Opportunities in Underground Physics (ISOUP) was held in Asilomar, CA during May 24-27, 2013. The Symposium brought together scientists from the US and abroad for an open discussion on science opportunities provided by the possibility of a new generation of large underground detectors associated with long baseline neutrino beams. The Symposium was highly successful. The main focus of the Symposium was the science goals that could be achieved by placing such a detector deep underground.

  9. Kick-off symposium series to help New Ph.D.s is a success

    Science.gov (United States)

    Chernys, Michael; Roughan, Moninya

    The U.S. National Science Foundation (NSF) and the U.S. Office of Naval Research (ONR) recently sponsored the first of what is expected to be many symposia to be held every couple of years to help new scientists begin their research careers. The inaugural dissertation symposium, Physical Oceanography Dissertation Symposium I (PODS I), provided a forum for new Ph.D.s and doctoral candidates soon to receive their degrees in physical oceanography or a related field, to discuss science and forge future professional relationships. The next symposium is expected to be in October 2003, in Hawaii, in concert with the Dissertation Symposium for Chemical Oceanographers (DISCO); information to be posted at http://spars.aibs.org/pods/. Applications from prospective participants were sought internationally, with the sponsoring agencies and coordinators advertising by e-mail, through personal communication with established researchers, and by informing degree-granting institutions in the related fields.

  10. Proceedings of radon and radon progeny measurements in Australia symposium

    International Nuclear Information System (INIS)

    Akber, R.A.; Harris, F.

    1994-01-01

    This publication contain papers presented at a symposium on radon and radon progeny measurements in Australia, held in Canberra on 18 February 1994. The emphasis was on results of measurements in different exposure situations, however information on methodology and techniques was also included. The scope of the symposium expanded through participation by scientists from China, French Polynesia and New Zealand. A list of participants and their organizations is included at the end of the proceedings. refs., tabs., figs

  11. Summary of the 4th Nordic Symposium on Digital Pathology.

    Science.gov (United States)

    Lundström, Claes; Waltersson, Marie; Persson, Anders; Treanor, Darren

    2017-01-01

    The Nordic symposium on digital pathology (NDP) was created to promote knowledge exchange across stakeholders in health care, industry, and academia. In 2016, the 4 th NDP installment took place in Linköping, Sweden, promoting development and collaboration in digital pathology for the benefit of routine care advances. This article summarizes the symposium, gathering 170 attendees from 13 countries. This summary also contains results from a survey on integrated diagnostics aspects, in particular radiology-pathology collaboration.

  12. Proceedings of JAEA-KPSI 8th symposium on advanced photon research

    International Nuclear Information System (INIS)

    2008-08-01

    JAEA-KPSI-APRC 8th Symposium on Advanced Photon Research was held at Kansai Photon Research Institute, Japan Atomic Energy Agency (JAEA-KPSI) in Kizu, Kyoto on June 4th - 5th, 2007. This report consists of contributed papers for the speeches and poster presentations in JAEA-KPSI-APRC 8th Symposium. The 33 of the presented papers are indexed individually. (J.P.N.)

  13. International Symposium on Interfacial Joining and Surface Technology (IJST2013)

    International Nuclear Information System (INIS)

    Takahashi, Yasuo

    2014-01-01

    Interfacial joining (bonding) is a widely accepted welding process and one of the environmentally benign technologies used in industrial production. As the bonding temperature is lower than the melting point of the parent materials, melting of the latter is kept to a minimum. The process can be based on diffusion bonding, pressure welding, friction welding, ultrasonic bonding, or brazing-soldering, all of which offer many advantages over fusion welding. In addition, surface technologies such as surface modification, spraying, coating, plating, and thin-film formation are necessary for advanced manufacturing, fabrication, and electronics packaging. Together, interfacial joining and surface technology (IJST) will continue to be used in various industrial fields because IJST is a very significant form of environmentally conscious materials processing. The international symposium of IJST 2013 was held at Icho Kaikan, Osaka University, Japan from 27–29 November, 2013. A total of 138 participants came from around the world to attend 56 oral presentations and 36 posters presented at the symposium, and to discuss the latest research and developments on interfacial joining and surface technologies. This symposium was also held to commemorate the 30th anniversary of the Technical Commission on Interfacial Joining of the Japan Welding Society. On behalf of the chair of the symposium, it is my great pleasure to present this volume of IOP Conference Series: Materials Science and Engineering (MSE). Among the presentations, 43 papers are published here, and I believe all of the papers have provided the welding community with much useful information. I would like to thank the authors for their enthusiastic and excellent contributions. Finally, I would like to thank all members of the committees, secretariats, participants, and everyone who contributed to this symposium through their support and invaluable effort for the success of IJST 2013. Yasuo Takahashi Chair of IJST 2013

  14. International Symposium on Interfacial Joining and Surface Technology (IJST2013)

    Science.gov (United States)

    Takahashi, Yasuo

    2014-08-01

    Interfacial joining (bonding) is a widely accepted welding process and one of the environmentally benign technologies used in industrial production. As the bonding temperature is lower than the melting point of the parent materials, melting of the latter is kept to a minimum. The process can be based on diffusion bonding, pressure welding, friction welding, ultrasonic bonding, or brazing-soldering, all of which offer many advantages over fusion welding. In addition, surface technologies such as surface modification, spraying, coating, plating, and thin-film formation are necessary for advanced manufacturing, fabrication, and electronics packaging. Together, interfacial joining and surface technology (IJST) will continue to be used in various industrial fields because IJST is a very significant form of environmentally conscious materials processing. The international symposium of IJST 2013 was held at Icho Kaikan, Osaka University, Japan from 27-29 November, 2013. A total of 138 participants came from around the world to attend 56 oral presentations and 36 posters presented at the symposium, and to discuss the latest research and developments on interfacial joining and surface technologies. This symposium was also held to commemorate the 30th anniversary of the Technical Commission on Interfacial Joining of the Japan Welding Society. On behalf of the chair of the symposium, it is my great pleasure to present this volume of IOP Conference Series: Materials Science and Engineering (MSE). Among the presentations, 43 papers are published here, and I believe all of the papers have provided the welding community with much useful information. I would like to thank the authors for their enthusiastic and excellent contributions. Finally, I would like to thank all members of the committees, secretariats, participants, and everyone who contributed to this symposium through their support and invaluable effort for the success of IJST 2013. Yasuo Takahashi Chair of IJST 2013

  15. International symposium 'Energetics 2004'. Symposium proceedings. Book 2; Megjunarodno sovetuvanje 'Energetika 2004'. Zbornik na referati. Kniga 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    The holding of this Symposium was initiated by ZEMAK - Macedonian Energy Association that for the last tens of years established itself in the national and international scientific and professional circles as a competent association of professionals with the main goal to follow, promote and improve the energy sector in the country. Having in mind the fact that the power energy sector as a fundamental sector plays a main role in the development and the improvement of the rest of the industry, and in the same time has a tremendous impact on the sustainable development of the entire economy of a country, power energy sector in fact has the paramount importance in the business environment of our country. Thus, ZEMAK has historically important role as a responsible and permanent driver, promoter and initiator for resolving of all-important questions directly or indirectly interconnected with the power energy sector in the country, and therefore the entire economy in the country as well. Following the past, ZEMAK had and would always have needs of organizing national and international symposiums and workshops as a panel where directly at one place national and international power energy experts could initiate, debate and resolve all up-to-date questions in the present energy sector in Macedonia, could analyze the modern world trends in the energy sector and try to find appropriate models for their application for further development and improvement of the energy sector in our country. This international symposium has the main goal to concentrate on a single place everybody who has power energy as a permanent preoccupation and/or vocation and professional interest. To aggregate on one place various experts, from the Academy and Universities, from the business circles and companies who are preoccupied with power energy directly or indirectly in their everyday life and work. During the Symposium more than 90 scientific and/or professional papers were presented and discussed

  16. International symposium 'Energetics 2004'. Symposium proceedings. Book 1; Megjunarodno sovetuvanje 'Energetika 2004'. Zbornik na referati. Kniga 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    The holding of this Symposium was initiated by ZEMAK - Macedonian Energy Association that for the last tens of years established itself in the national and international scientific and professional circles as a competent association of professionals with the main goal to follow, promote and improve the energy sector in the country. Having in mind the fact that the power energy sector as a fundamental sector plays a main role in the development and the improvement of the rest of the industry, and in the same time has a tremendous impact on the sustainable development of the entire economy of a country, power energy sector in fact has the paramount importance in the business environment of our country. Thus, ZEMAK has historically important role as a responsible and permanent driver, promoter and initiator for resolving of all-important questions directly or indirectly interconnected with the power energy sector in the country, and therefore the entire economy in the country as well. Following the past, ZEMAK had and would always have needs of organizing national and international symposiums and workshops as a panel where directly at one place national and international power energy experts could initiate, debate and resolve all up-to-date questions in the present energy sector in Macedonia, could analyze the modern world trends in the energy sector and try to find appropriate models for their application for further development and improvement of the energy sector in our country. This international symposium has the main goal to concentrate on a single place everybody who has power energy as a permanent preoccupation and/or vocation and professional interest. To aggregate on one place various experts, from the Academy and Universities, from the business circles and companies who are preoccupied with power energy directly or indirectly in their everyday life and work. During the Symposium more than 90 scientific and/or professional papers were presented and discussed

  17. Proceeding of the third symposium of large data management for creative research

    International Nuclear Information System (INIS)

    Ueshima, Yutaka

    2002-06-01

    This report consists of 11 contributed papers of the Third Symposium of Large Data Management for Creative Research, which was held at the JAERI Advanced Photon Research Center in Kyoto on October 29-31. The number of oral presentations was 14. This proceeding includes copies of slides from the first and second symposium. (author)

  18. Lillie Martin in Gottingen. Lillie Martin, Outstanding Scholar and Teacher: A Centennial Symposium.

    Science.gov (United States)

    Adler, Helmut E.

    This article reports on a symposium commemorating Lillien Martin's dissertation, "Analysis of Difference Sensations," by published in 1899. The symposium marked the centenary celebration in acknowledgement of Martin's pioneer efforts for women in the field of psychology. Psychophysics was concerned with the quantitative assessment of…

  19. Proceedings of the first symposium on utilization of research reactors and JMTR

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The first symposium on utilization of research reactors (JRR-2, JRR-3M, JRR-4) and Japan Materials Testing Reactor (JMTR) in JAERI was held from September 29th to 30th, 1997 at Sannomaru Hotel, Mito. The purpose of this symposium is to announce contribution to progress of scientific technology as well as to promote future utilization of the research reactors and JMTR. During the symposium, 16 reports were presented on nuclear fuel and material, neutron beam experiment, medical irradiation, radioisotope production and neutron activation analysis. The present status of the research reactors and JMTR were also reported. The special lecture titled `JRR-2 and Medical Irradiation` was given by Mr. Nakamura, former editorial writer of Yomiuri. Finally, panel discussion was carried on `The Role of Research Reactors and JMTR in Scientific Technology for the future` actively by the participants and experts in every field of research reactor utilization. 250 people participated in this symposium from universities, national research institutes, private corporations and JAERI. This proceedings briefly summarizes 16 reports, the content of panel discussion and so forth. (J.P.N.)

  20. Proceedings of the fourth symposium of large data management for creative research

    International Nuclear Information System (INIS)

    Ueshima, Yutaka

    2004-03-01

    This report consists of 10 contributed papers of the Fourth Symposium of Large Data Management for Creative Research, which was held at the JAERI Advanced Photon Research Center in Kyoto on September 2-4, 2002. The aim of the symposium is for private sector and public research organization researchers to report on the latest research and technology developments and perform information exchange about large data treatment, experiments with visualization and large data management as a support the base for research. The contents of the symposium are speeches, panel-discussions, the laboratory, supercomputer and photon science museum annex tours. There were seven private sector speeches and ten university and research organization speeches. There were seventeen speeches in total. A total of 117 people participated including 95 participants from other than JAERI. The symposium showed the present condition and view of large data management technology which is important for computer science, advanced photon research and became a valuable forum from the stand point as an indicator for future research. The 5 of the presented papers are indexed individually. (J.P.N.)

  1. Symposium: What Is College English?

    Science.gov (United States)

    Bloom, Lynn Z.; White, Edward M.; Enoch, Jessica; Hawk, Byron

    2013-01-01

    This symposium explores the role(s) College English has (or has not) had in the scholarly work of four scholars. Lynn Bloom explores the many ways College English influenced her work and the work of others throughout their scholarly lives. Edward M. White examines four articles he has published in College English and draws connections between…

  2. Proceedings of international symposium on radiation education (ISRE 98)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-09-01

    The International Symposium on Radiation Education, which commemorates the centenary of the discovery of radium by the Curies, was held on December 11-14, 1998 in Kanagawa, Japan. At present, radiation and radioactivity are not indispensable in medical diagnosis and treatment, but also are widely used in scientific research and industrial activities. Nuclear power generation is also playing an important role in saving nonrenewable natural energy resources, and without producing the potentially hazardous carbon dioxide. However, a majority of people has a insufficient knowledge or information about radiation and radioactivity. The symposium intended to generalize the scientific knowledge about radiation and radioactivity and also about various aspects of risks associated with the life in the civilized society, by discussing how to improve education in general and young generations at schools in particular, and by exchanging the newest scientific information relevant to the education. The symposium consisted of 5 sessions with 61 submitted papers, and involved about 170 participants from Australia, Bangladesh, France, Germany, Hungary, Indonesia, Korea, Philippine, Pakistan, Thailand, Turkey, UK and USA. (author)

  3. Proceedings of the fifteenth symposium on energy engineering sciences

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-11-01

    This Proceedings Volume includes the technical papers that were presented during the Fifteenth Symposium on Energy Engineering Sciences on May 14-15, 1997, at Argonne National Laboratory, Argonne, Illinois. The Symposium was organized into eight technical sessions, which included 32 individual presentations followed by discussion and interaction with the audience. The topics of the eight sessions are: multiphase flows 1; multiphase flows 2; mostly optics; fluid mechanics; nonlinear fields; welding and cracks; materials; and controls. The DOE Office of Basic Energy Sciences, of which Engineering Research is a component program, is responsible for the long-term mission-oriented research in the Department. It has the prime responsibility for establishing the basic scientific foundation upon which the Nation`s future energy options will have to be identified, developed, and built. It is committed to the generation of new knowledge necessary for the solution of present and future problems of energy exploration, production, conversion, and utilization, consistent with respect for the environment. Separate abstracts have been indexed into the energy database for contributions to this Symposium.

  4. Overview (this manuscript is an overview of an ASTM symposium. The authors, John Sebroski and Mark Mason, of the overview were the co-chairs of the symposium and co-editors of the manuscripts submitted for ASTM peer review and subsequent publication in the technical proceedings for the symposium)

    Science.gov (United States)

    The Symposium on Developing Consensus Standards for Measuring Chemical Emissions from Spray Polyurethane Foam (SPF) Insulation was held on April 30th and May 1, 2015. Sponsored by ASTM Committee D22 on Air Quality, the symposium was held in Anaheim, CA, in conjunction with the st...

  5. Second invitational well-testing symposium proceedings

    Energy Technology Data Exchange (ETDEWEB)

    1978-01-01

    The symposium dealt with the state of the art of injection of fluids underground, and its application to geothermal systems in particular. Separate abstracts were prepared for fourteen papers and three abstracts of papers were listed by title. Three papers were previously abstracted for EDB.

  6. Proceedings of the 8th Japan-China bilateral symposium on radiation chemistry

    Energy Technology Data Exchange (ETDEWEB)

    Yamaoka, Hitoshi; Hase, Hirotomo; Makuuchi, Keizou [eds.

    2000-03-01

    This issue is the collection of papers presented at The 8th Japan-China Bilateral Symposium on Radiation Chemistry held on October 25-29, 1999 at Kyodai Kaikan in Kyoto. The total number of the contributed papers is 69 which consists of 41 and 28 papers for oral and poster presentations, respectively. The papers presented are classified into five categories: A: Radiation Chemistry - Fundament (21 papers), B: Radiation Chemistry - Polymer (10 papers), C: Radiation Chemistry - Biological System (8 papers), D: Radiation Processing (19 papers), and E: Advanced Radiation Chemistry - Ion Beams and Positron (11 papers). The output of the Symposium and the history of the Bilateral Symposium were compiled in the Closing. (J.P.N.)

  7. SYMPOSIUM: Rare decays

    International Nuclear Information System (INIS)

    Anon.

    1989-01-01

    Late last year, a symposium entitled 'Rare Decays' attracted 115 participants to a hotel in Vancouver, Canada. These participants were particle physicists interested in checking conventional selection rules to look for clues of possible new behaviour outside today's accepted 'Standard Model'. For physicists, 'rare decays' include processes that have so far not been seen, explicitly forbidden by the rules of the Standard Model, or processes highly suppressed because the decay is dominated by an easier route, or includes processes resulting from multiple transitions

  8. Conference Report: 6th Annual International Symposium on Regenerative Rehabilitation.

    Science.gov (United States)

    Loghmani, M Terry; Roche, Joseph A

    2018-04-03

    The 6th International Symposium on Regenerative Rehabilitation, hosted by the Alliance for Regenerative Rehabilitation Research and Training (AR 3 T), included a preconference meeting of institutional representatives of the International Consortium of Regenerative Rehabilitation, keynote talks from distinguished scientists, platform and poster presentations from experts and trainees, panel discussions and postconference workshops. The following priorities were identified: increasing rigor in basic, preclinical and clinical studies, especially the use of better controls; developing better outcome measures for preclinical and clinical trials; focusing on developing more tissue-based interventions versus cell-based interventions; including regenerative rehabilitation in curricula of professional programs like occupational and physical therapy; and developing better instruments to quantify rehabilitative interventions.

  9. Summary of the 4th nordic symposium on digital pathology

    Directory of Open Access Journals (Sweden)

    Claes Lundström

    2017-01-01

    Full Text Available The Nordic symposium on digital pathology (NDP was created to promote knowledge exchange across stakeholders in health care, industry, and academia. In 2016, the 4th NDP installment took place in Linköping, Sweden, promoting development and collaboration in digital pathology for the benefit of routine care advances. This article summarizes the symposium, gathering 170 attendees from 13 countries. This summary also contains results from a survey on integrated diagnostics aspects, in particular radiology-pathology collaboration.

  10. Symposium on risk assessment and adoption of decisions: VALDOR-2001

    International Nuclear Information System (INIS)

    Kovalevich, O.M.

    2001-01-01

    The symposium was held in Stockholm (Sweden), 9 - 15 June 2001. Reports involved following fundamental problems: prospects for radioactive waste management, investigations into risk control, risk control and regulations, bases for risk assessment, the role of mass media and participation of the community in adoption of complex decisions. Much attention at the symposium is given to radioactive wastes, radiation sources, risk of chemical plants and risk assessment in biotechnology. Practically all reports were devoted to relations with the community [ru

  11. 1979 DOE statistical symposium

    International Nuclear Information System (INIS)

    Gardiner, D.A.; Truett, T.

    1980-09-01

    The 1979 DOE Statistical Symposium was the fifth in the series of annual symposia designed to bring together statisticians and other interested parties who are actively engaged in helping to solve the nation's energy problems. The program included presentations of technical papers centered around exploration and disposal of nuclear fuel, general energy-related topics, and health-related issues, and workshops on model evaluation, risk analysis, analysis of large data sets, and resource estimation

  12. 1979 DOE statistical symposium

    Energy Technology Data Exchange (ETDEWEB)

    Gardiner, D.A.; Truett T. (comps. and eds.)

    1980-09-01

    The 1979 DOE Statistical Symposium was the fifth in the series of annual symposia designed to bring together statisticians and other interested parties who are actively engaged in helping to solve the nation's energy problems. The program included presentations of technical papers centered around exploration and disposal of nuclear fuel, general energy-related topics, and health-related issues, and workshops on model evaluation, risk analysis, analysis of large data sets, and resource estimation.

  13. Proceedings of 1. international symposium on applied isotope geochemistry (AIG-1)

    International Nuclear Information System (INIS)

    Aaberg, G.; Joergensen, E.B.

    1993-09-01

    The publication is a compilation of abstracts from the ''1. international symposium on applied isotope geochemistry (AIG-1)'' in Norway. The symposium was the first of its kind taking up different applications of most of the available isotopic systems and thus covered a wide range of topics from: 1) Water resources, hydrology, geomedicine and environmental problems, 2) Petroleum exploration and production, 3) Mineral exploration and 4) Analytical methods

  14. Proceedings of 11th Symposium of the Croatian Radiation Protection Association

    International Nuclear Information System (INIS)

    Radolic, V.; Poje Sovilj, M.; Krajcar Bronic, I.

    2017-01-01

    The 11th symposium of the Croatian Radiation Protection Association discussed the following topics: ethics and culture in radiation protection; general topics; radiation protection and dosimetry in medicine; biological effects of radiation; instrumentation and measuring techniques; radioecology; public exposure; radon; non-ionising radiation. For each subject many investigations, experiments, examples and results are presented. International character of this symposium shows importance of these topics not only in region but world wide.

  15. 3rd International Symposium Mathematical Progress in Expressive Image Synthesis

    CERN Document Server

    Ochiai, Hiroyuki

    2016-01-01

    “Progress in Expressive Image Synthesis” (MEIS2015), was held in Fukuoka, Japan, September 25–27, 2015. The aim of the symposium was to provide a unique venue where various issues in computer graphics (CG) application fields could be discussed by mathematicians, CG researchers, and practitioners. Through the previous symposiums MEIS2013 and MEIS2014, mathematicians as well as CG researchers have recognized that CG is a specific and practical activity derived from mathematical theories. Issues found in CG broaden the field of mathematics and vice versa, and CG visualizes mathematical theories in an aesthetic manner. In this volume, the editors aim to provoke interdisciplinary research projects through the peer-reviewed papers and poster presentations at the this year’s symposium. This book captures interactions among mathematicians, CG researchers, and practitioners sharing important, state-of-the-art issues in graphics and visual perception. The book is suitable for all CG researchers seeking open pro...

  16. Proceedings of the 2000 symposium on nuclear data

    Energy Technology Data Exchange (ETDEWEB)

    Yamano, Naoki [Sumitomo Atomic Energy Industries, Ltd., Tokyo (Japan); Fukahori, Tokio [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2001-03-01

    The 2000 Symposium on Nuclear Data was held at Tokai Research Establishment, Japan Atomic Energy Research Institute (JAERI), on 16th and 17th of November 2000. Japanese Nuclear Data Committee and Nuclear Data Center, JAERI organized this symposium. In the oral sessions, presented were 18 papers on topics of recent experiments, status of JENDL-3.3 and JENDL High Energy File, benchmark tests of JENDL-3.2, international activities and other subjects. In the poster session, presented were 40 papers concerning experiments, evaluations, benchmark tests and on-line database on nuclear data. Those presented papers are compiled in the proceedings. The 58 of the presented papers are indexed individually. (J.P.N.)

  17. Summary of third Nordic symposium on digital pathology.

    Science.gov (United States)

    Lundström, Claes; Waltersson, Marie; Persson, Anders; Treanor, Darren

    2016-01-01

    Cross-disciplinary and cross-sectorial collaboration is a key success factor for turning the promise of digital pathology into actual clinical benefits. The Nordic symposium on digital pathology (NDP) was created to promote knowledge exchange in this area, among stakeholders in health care, industry, and academia. This article is a summary of the third NDP symposium in Linkφping, Sweden. The Nordic experiences, including several hospitals using whole-slide imaging for substantial parts of their primary reviews, formed a fertile base for discussions among the 190 NDP attendees originating from 15 different countries. This summary also contains results from a survey on adoption and validation aspects of clinical digital pathology use.

  18. Summary of third Nordic symposium on digital pathology

    Directory of Open Access Journals (Sweden)

    Claes Lundstrom

    2016-01-01

    Full Text Available Cross-disciplinary and cross-sectorial collaboration is a key success factor for turning the promise of digital pathology into actual clinical benefits. The Nordic symposium on digital pathology (NDP was created to promote knowledge exchange in this area, among stakeholders in health care, industry, and academia. This article is a summary of the third NDP symposium in Linkφping, Sweden. The Nordic experiences, including several hospitals using whole-slide imaging for substantial parts of their primary reviews, formed a fertile base for discussions among the 190 NDP attendees originating from 15 different countries. This summary also contains results from a survey on adoption and validation aspects of clinical digital pathology use.

  19. 12. 'Tihany' symposium on radiation chemistry. Program and abstracts

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    The 12th 'Tihany' symposium on radiation chemistry was held in Zalakaros in the organization of the Hungarian Academy of Sciences, Institute of Isotope and Surface Chemistry. The scientific program of the Symposium will cover all the major disciplines of both basic and applied radiation chemistry. The topics were the fundamental processes in radiation chemistry, the different irradiations ways, radiolysis of inorganic and organic systems, nanoscale and the macromolecular systems. Also could be seen presentations in the subject of the food irradiation, the environmental protection, biomedical materials radiation, about the resistant materials, the radiation sterilization and the dosimetry. (S.I.)

  20. 12. 'Tihany' symposium on radiation chemistry. Program and abstracts

    International Nuclear Information System (INIS)

    2011-01-01

    The 12th 'Tihany' symposium on radiation chemistry was held in Zalakaros in the organization of the Hungarian Academy of Sciences, Institute of Isotope and Surface Chemistry. The scientific program of the Symposium will cover all the major disciplines of both basic and applied radiation chemistry. The topics were the fundamental processes in radiation chemistry, the different irradiations ways, radiolysis of inorganic and organic systems, nanoscale and the macromolecular systems. Also could be seen presentations in the subject of the food irradiation, the environmental protection, biomedical materials radiation, about the resistant materials, the radiation sterilization and the dosimetry. (S.I.)

  1. Proceedings of the eighth Symposium of Atomic Energy Research

    International Nuclear Information System (INIS)

    Vidovszky, I.

    1998-10-01

    These are the remaining 9 papers, presented on the eighth Symposium of Atomic Energy Research, held in Bystrice nad Perstejnem, Czech Republic, 21-25 September 1998. The papers are presented in their original form, i. e. no corrections or modifications were carried out. The content of this volume is divided into thematic groups: Spectral and Core Calculation Methods, Core Design, Operation and Fuel Management, Core Monitoring, Surveillance and Testing, Neutron Kinetics and reactor Dynamics Methods, Safety Issues and Analysis, Rod Drop Reactivity Measurements, Criticality safety, Spent Fuel and Decommissioning, - according to the presentation sequence on the Symposium

  2. Proceedings of the twentieth symposium of atomic energy research

    International Nuclear Information System (INIS)

    Vidovszky, I.

    2010-10-01

    The present volume contains 69 papers, presented on the twentieth symposium of atomic energy research, held in Hanasaari, Espoo, Finland, 20-24 September 2010. The papers are presented in their original form, i. e. no corrections or modifications were carried out. The content of this volume is divided into thematic groups: Fuel Management, Spectral and Core Calculations, Core Surveillance and Monitoring, CFD Analysis, Reactor Dynamics Thermal Hydraulics and Safety Analysis, Physical Problems of Spent Fuel Decommissioning and Radwaste, Actinide Transmutation and Spent Fuel Disposal, Core Operation, Experiments and Code Validation - according to the presentation sequence on the Symposium. (Author)

  3. Proceedings of the 16. Symposium of Atomic Energy Research

    International Nuclear Information System (INIS)

    Vidovszky, Istvan

    2006-10-01

    The present volume contains 56 papers, presented on the sixteenth Symposium of Atomic Energy Research, held in Bratislava, Slovakia, 25-29 September 2006. The papers are presented in their original form, i. e. no corrections or modifications were carried out. The content of this volume is divided into thematic groups: Spectral and Core Calculation, Core Operation Experiments and Code Validation, Fuel Management, Core Surveillance and Monitoring, Reactor Dynamics Thermal Hydraulics and Safety Analysis, Physical Problems of Spent Fuel Decommissioning, and Radwaste, Actinide Transmutation and Spent Fuel Disposal - according to the presentation sequence on the Symposium (Author)

  4. 4th international interdisciplinary chaos symposium

    CERN Document Server

    Banerjee, Santo; Caglar, Suleyman; Ozer, Mehmet; Chaos and complex systems

    2013-01-01

    Complexity Science and Chaos Theory are fascinating areas of scientific research with wide-ranging applications.  The interdisciplinary nature and ubiquity of complexity and chaos are features that provides scientists with a motivation to pursue general theoretical tools and frameworks. Complex systems give rise to emergent behaviors, which in turn produce novel and interesting phenomena in science, engineering, as well as in the socio-economic sciences. The aim of all Symposia on Chaos and Complex Systems (CCS) is to bring together scientists, engineers, economists and social scientists, and to discuss the latest insights and results obtained in the area of corresponding nonlinear-system complex (chaotic) behavior. Especially for the “4th International Interdisciplinary Chaos Symposium on Chaos and Complex Systems,” which took place April 29th to May 2nd, 2012 in Antalya, Turkey, the scope of the symposium had been further enlarged so as to encompass the presentation of work from circuits to econophysic...

  5. Proceedings of symposium on technology in laboratories by department of engineering and technical services

    International Nuclear Information System (INIS)

    1994-07-01

    The Symposium on Technology in Laboratories was held on March 23 and 24 at Ceratopia Toki, and Toki Chamber of Commerce and Industry in Toki city, Gifu Prefecture, Japan. This symposium was hosted by National Institute for Fusion Science (NIFS). There were 273 participants from many Japanese universities and laboratories, from some Japanese industrial world. Seventy eight papers were presented in the symposium. Technical experience and new techniques were reported and discussed being divided into five sessions; technologies of fabrication, cryogenics, diagnostic and control system, computer and experimental apparatus. (author)

  6. Proceedings of symposium on technology in laboratories by department of engineering and technical services

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-06-01

    The Symposium on Technology in Laboratories was held on March 14 and 15 at Ceratopia Toki in Toki City, Gifu Prefecture, Japan. This symposium was hosted by National Institute for Fusion Science (NIFS). There were 407 participants from many Japanese universities, national laboratories, technical colleges and from some Japanese Industrial world. One hundred and thirty one papers were presented in the symposium. Technical experience and new techniques were reported and discussed being divided into five sessions; technology of fabrication, device technology, diagnostic and control system, cryogenics, computer and data processing. (author)

  7. IUTAM Symposium

    CERN Document Server

    Bui, Huy

    1993-01-01

    Inverse problems occur in a wide variey of fields. In general, the inverse problem can be defined as one where one should estimate the cause from the result, while the direct problem is concerned with how to obtain the result from the cause. The aim of this symposium was to gather scientists and researchers in engineering mechanics concerned with inverse problems in order to exchange research result and develop computational and experimentalapproaches to solve inverse problems. The contributions in this volume cover the following subjects: mathematical and computational aspects of inverse problems, parameter or system identification, shape determination, sensitivity analysis, optimization, material property characterization, ultrasonic nondestructive testing, elastodynamic inverse problems, thermal inverse problems, and other miscellaneous engineering applications.

  8. PREFACE: The 8th China International NanoScience and Technology Symposium

    Science.gov (United States)

    Cong, Hailin

    2009-09-01

    The 8th China International NanoScience and Technology Symposium, Xiangtan (2009) - Nano-products Exposition, sponsored by Chinese Society of Miro-nanoTechnology and IEEE Nanotechnology Council, etc will be held on 23-27 October 2009 in Xiangtan, China. This symposium is held in order to promote the technology for the development of micro- and nano-scale, cross-scale integration, to share new micro/nano technologies, to exchange information and knowledge over all fields and promote the industrialization and development of nanotechnology. This is a leading professional and traditional conference with at least 400 participants every year. Famous experts, professors and government officials at home and abroad will give lectures during the symposium, which provides a good platform for delegates to discover the latest developments and dynamics of nanotechnology. Researchers, teachers and students in colleges, and technical personnel in the industrial community are welcome to contribute and actively participate in the symposium. In our last symposium held in 2008, over 600 participants from all over the world attended, and we received over 570 abstract and paper submissions for the proceedings published in different languages in famous professional journals. And this year, we have already received over 400 submissions. After strict peer review, 60 of them are published in this volume of Journal of Physics: Conference Series. We are confident that the event will be even more successful this year. Consequently, the organizing committee and proceedings editorial committee would like to thank our colleagues at the IOP Publishing, the invited speakers, our sponsors and all the delegates for their great contributions in this conference. Hailin Cong Vice Chair of the proceedings editorial committee

  9. 1st International Symposium on Stress-Associated RNA Granules in Human Disease and Viral Infection

    Directory of Open Access Journals (Sweden)

    Bruce W. Banfield

    2014-09-01

    Full Text Available In recent years, important linkages have been made between RNA granules and human disease processes. On June 8-10 of this year, we hosted a new symposium, dubbed the 1st International Symposium on Stress-Associated RNA Granules in Human Disease and Viral Infection. This symposium brought together experts from diverse research disciplines ranging from cancer and neuroscience to infectious disease. This report summarizes speaker presentations and highlights current challenges in the field.

  10. Proceedings of the Fifth Symposium of the Croatian Radiation Protection Association

    International Nuclear Information System (INIS)

    Krajcar Bronic, I.; Miljanic, S.; Obelic, B.

    2003-01-01

    Croatian Radiation Protection Association (CRPA) organised symposium with international participation. Co-organisers (Rudjer Boskovic Institute, Zagreb, Croatia and Institute for Medical Research and Occupational Health, Zagreb, Croatia) show importance of this symposium, which was under the auspices of several ministries (Ministry of Economy, Ministry of Environmental Protection and Physical Planning, Ministry of Health, Ministry of Science and Technology of the Republic of Croatia) and State Office for Standardization and Metrology. All topics are of great interest for Croatia. They present recent researches in Croatia and in other almost same oriented countries in Europe.The distribution of topics at the Fifth symposium shows same parts with articles from radioecology and radon, biological and medical topics, as well as professional and public exposure and dosimetry. Also, non-ionising radiations take its share as very interesting topics at present. (S.P.)

  11. Proceedings of the 2009 IAGT symposium : innovative and reliable energy solutions

    International Nuclear Information System (INIS)

    2009-01-01

    This symposium hosted by the Industrial Application of Gas Turbines (IAGT) Committee, provided a forum to review new developments in the industrial application of gas turbines in Canada. The sectors of industry involved at the symposium included research and development, application, performance, operation, maintenance and user experience. Both technical presentations and expert panel discussions focused on the challenging issues facing industrial gas turbine operations in power generation as well as oil and gas applications. Operational experiences with gas turbines were highlighted with reference to mechanical efficiency, power performance, maintenance and reliability as well as their ability to reduce emissions to the environment. The sessions were entitled: fuel combustion and emissions; cogeneration, gasification and power applications; reliability and applications in the oil sands. The symposium featured 21 presentations, of which 18 have been catalogued separately for inclusion in this database. refs., tabs., figs.

  12. National symposium on food irradiation

    International Nuclear Information System (INIS)

    Beyers, M.; Brodrick, H.T.; Van Niekerk, W.C.A.

    1980-01-01

    This report contains proceedings of papers delivered at the national symposium on food irradiation held in Pretoria. The proceedings have been grouped into the following sections: general background; meat; agricultural products; marketing; and radiation facilities - cost and plant design. Each paper has been submitted separately to INIS. Tables listing irradiated food products cleared for human consumption in different countries are given

  13. AAAI 1993 Fall Symposium Reports

    OpenAIRE

    Levinson, Robert; Epstein, Susan; Terveen, Loren; Bonasso, R. Peter; Miller, David P.; Bowyer, Kevin; Hall, Lawrence

    1994-01-01

    The Association for the Advancement of Artificial Intelligence held its 1993 Fall Symposium Series on October 22-24 in Raleigh, North Carolina. This article contains summaries of the six symposia that were conducted: Automated Deduction in Nonstandard Logics; Games: Planning and Learning; Human-Computer Collaboration: Reconciling Theory, Synthesizing Practice; Instantiating Intelligent Agents; and Machine Learning and Computer Vision: What, Why, and How?

  14. XI International Symposium on Radiation from Relativistic Electrons in Periodic Structures (RREPS2015)

    International Nuclear Information System (INIS)

    2016-01-01

    These Proceedings are published as a recollection of contributions presented at the XI International Symposium on “Radiation from Relativistic Electrons in Periodic Structures” (RREPS-15), which was held in Saint Petersburg, September 6-11, 2015, Russian Federation. RREPS-15 was co-organized by Saint-Petersburg State University, National Research Tomsk Polytechnic University, and National Research Nuclear University (MEPhI). The main goal of the symposium was to bring together the scientists from around the world who work on designs of new radiation sources and their applications. There were 108 participants registered from 12 countries. The website of the symposium is available at http://rreps.tpu.ru/. (paper)

  15. 12th Rencontres du Vietnam: 36th International symposium on Physics in Collision

    CERN Document Server

    2016-01-01

    The XXXVI international symposium on Physics in Collision (PIC) is a conference whose focus is to update key topics in elementary particle physics in which new results have been published within the last year or are reasonably expected to be so before the symposium. The aim of the presentations is to encourage informal discussions of new experimental results and their implications. The topics at the symposium cover a wide range of physics subjects from experimental and theoretical accelerator-based particle physics to astroparticle physics. Specifically, the meeting topics include Electroweak phenomena, neutrino physics, QCD, heavy flavor physics, heavy ion physics, Higgs physics, Searches for BSM physics, and astroparticle physics.

  16. Tritium in the Physical and Biological Sciences. V. 1. Proceedings of a Symposium

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1962-01-15

    The use of tritium for research in physics, chemistry, biology and hydrology has in recent years become increasingly important. It was for this reason that the first international conference to discuss the progress of new developments was organized by the IAEA in conjunction with the Joint Commission on Applied Radioactivity and held from 3-10 May 1961, in Vienna. The first five sessions of the Symposium were devoted to the use of tritium in hydrology, physics and chemistry. Special emphasis was laid on the role of tritium as a tracer in hydrology, especially in the study of water movement. The establishment and improvement of counting and detection techniques to facilitate the application of tritium as a tracer was another aspect discussed in this part of the proceedings. Papers were read on the preparation of tritiated compounds and it was generally agreed that further clarification of the mechanism of various techniques, and of the Wilzbach gas exposure technique in particular, would lead to further developments in the synthesis of a number of tritium compounds important in biology. Other papers were concerned with tritium applications to studies of the mechanism of some chemical reactions together with the effects of tritium isotopes. During the second part of the Symposium the biological applications of tritium and tritiated compounds were discussed. These included general problems connected with the biological uses of tritium and the radiation effects of tritium on living organisms such as viruses, bacteria and cancer cells. The value of tritium in biological studies became apparent because of the ease with which a large number of metabolically active compounds such as hormones, vitamins and other important constituents in the body can be labelled with tritium. Tritium is also a weak beta-emitter and autoradiographie s of tissues and single cells containing tritium-labelled compounds allow an excellent localization of the tracer. The Symposium was attended by

  17. IUTAM Symposium on Surface Effects in the Mechanics of Nanomaterials and Heterostructures : Proceedings of the IUTAM Symposium

    CERN Document Server

    Wang, Jianxiang

    2013-01-01

    This volume constitutes the proceedings of the IUTAM Symposium on Surface Effects in the Mechanics of Nanomaterials and Heterostructures, held in Beijing, 8-12 August, 2010. The symposium brought together the most active scientists working in this area from the fields of solid mechanics, composites, physics, and materials science and summarized the state-of-the-art research results with a view to advancing the frontiers of mechanics and materials physics.         Nanomaterials and heterostructures have a large fraction of their atoms at surfaces and  interfaces. These atoms see a different environment to those in the interior and can have a substantial effect on the overall mechanical and physical behaviour of a material. The last decade has witnessed a growing interest in the study of surfaces and how the surface behaviour couples with that of the bulk to determine the overall system response. The papers in this proceedings cover: extension of continuum mechanics and thermodynamics to the nano-scale; ...

  18. Land Subsidence International Symposium held in Venice

    Science.gov (United States)

    The Third International Symposium on Land Subsidence was held March 18-25, 1984, in Venice, Italy. Sponsors were the Ground-Water Commission of the International Association of Hydrological Sciences (IAHS), the United Nations Educational, Scientific, and Cultural Organization (UNESCO), the Italian National Research Council (CNR), the Italian Regions of Veneto and Emilia-Romagna, the Italian Municipalities of Venice, Ravenna, and Modena, the Venice Province, and the European Research Office. Cosponsors included the International Association of Hydrogeologists (IAH), the International Society for Soil Mechanics and Foundation Engineering (ISSMFE), and the Association of Geoscientists for International Development (AGID).Organized within the framework of UNESCO's International Hydrological Program, the symposium brought together over 200 international interdisciplinary specialists in the problems of land subsidence due to fluid and mineral withdrawal. Because man's continuing heavy development of groundwater, gas, oil, and minerals is changing the natural regime and thus causing more and more subsiding areas in the world, there had been sufficient new land subsidence occurrence, problems, research, and remedial measures since the 1976 Second International Symposium held in Anaheim, California, to develop a most interesting program of nearly 100 papers from about 30 countries. The program consisted of papers covering case histories of fluid and mineral withdrawal, engineering theory and analysis, karst “sink-hole”-type subsidence, subsidence due to dewatering of organic deposits or due to application of water (hydrocompaction), instrumentation, legal, socioeconomic, and environmental effects of land subsidence, and remedial works.

  19. The Symposium of Philo’s Therapeutae: Displaying Jewish Identity in an Increasingly Roman World

    Directory of Open Access Journals (Sweden)

    Maren R. Niehoff

    2010-11-01

    Full Text Available Philo's description of the sober Jewish symposium in De vita contempletiva resembles the attitude of the contemporary elite in Rome and caps a growing disparagement of the traditional Greek symposium that can be traced through his earlier writings.

  20. Self-organization in Complex Systems The Past, Present, and Future of Synergetics : International Symposium

    CERN Document Server

    Pelster, Axel

    2016-01-01

    This proceedings volume contains talks and poster presentations from the International Symposium "Self-Organization in Complex Systems: The Past, Present, and Future of Synergetics", which took place at Hanse-Wissenschaftskolleg, an Institute of Advanced Studies, in Delmenhorst, Germany, during the period November 13 - 16, 2012. The Symposium was organized in honour of Hermann Haken, who celebrated his 85th birthday in 2012. With his fundamental theory of Synergetics he had laid the mathematical-physical basis for describing and analyzing self-organization processes in a diversity of fields of research. The quest for common and universal principles of self-organization in complex systems was clearly covered by the wide range of interdisciplinary topics reported during the Symposium. These extended from complexity in classical systems and quantum systems over self-organisation in neuroscience even to the physics of finance. Moreover, by combining a historical view with a present status report the Symposium con...

  1. Symposium on high spin phenomena in nuclei

    International Nuclear Information System (INIS)

    1979-10-01

    Separate abstracts were prepared for 44 of the papers given at this symposium. Six other papers have already been cited in ERA; these papers can be located by reference to the entry CONF-790323 - in the Report Number Index

  2. Fifth German-American Frontiers of Engineering Symposium

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2002-05-01

    The agenda book for the Fifth German-American Frontiers of Engineering Symposium contains abstracts of the 16 presentations as well as information on the program, bios of the speakers, contact information for all attendees, and background on the activity.

  3. PREFACE: 3rd International Symposium ''Optics and its Applications''

    Science.gov (United States)

    Calvo, M. L.; Dolganova, I. N.; Gevorgyan, N.; Guzman, A.; Papoyan, A.; Sarkisyan, H.; Yurchenko, S.

    2016-01-01

    The SPIE.FOCUS Armenia: 3rd International Symposium ''Optics and its Applications'' (OPTICS-2015) http://rau.am/optics2015/ was held in Yerevan, Armenia, in the period October 1 - 5, 2015. The symposium was organized by the International Society for Optics and Photonics (SPIE), the Armenian SPIE student chapter with collaboration of the Armenian TC of ICO, the Russian-Armenian University (RAU), the Institute for Physical Research of National Academy of Sciences of Armenia (IPR of NAS), the Greek-Armenian industrial company LT-PYRKAL, and the Yerevan State University (YSU). The Symposium was co-organized by the SPIE & OSA student chapters of BMSTU, the Armenian OSA student chapter, and the SPIE student chapters of Lund University and Wroclaw University of Technology. The symposium OPTICS-2015 was dedicated to the International Year of Light and Light-Based Technologies. OPTICS-2015 was devoted to modern topics and optical technologies such as: optical properties of nanostructures, silicon photonics, quantum optics, singular optics & its applications, laser spectroscopy, strong field optics, biomedical optics, nonlinear & ultrafast optics, photonics & fiber optics, and mathematical methods in optics. OPTICS-2015 was attended by 100 scientists and students representing 17 countries: Armenia, China, Czech Republic, France, Georgia, Germany, India, Iran, Italy, Latvia, Mexico, Poland, Russia, Saudi Arabia, Sweden, Ukraine, and USA. Such a broad international community confirmed the important mission of science to be a uniting force between different countries, religions, and nations. We hope that OPTICS-2015 inspired and motivated students and young scientists to work in optics and in science in general. The present volume of Journal of Physics: Conference Series includes proceedings of the symposium covering various aspects of modern problems in optics. We are grateful to all people who were involved in the organization process. We gratefully acknowledge support from

  4. The seventh international symposium on radiopharmacology

    International Nuclear Information System (INIS)

    1991-01-01

    Abstracts are presented from the symposium on radiopharmacology. Sessions included: pharmokinetics of Tc-99m labeled agents; pharmokinetics and tumor imaging; miscellaneous pharmokinetic studies; pharmokinetics of brain/receptor imaging; pharmokinetics of radiolabeled antibodies; pharmokinetics of radiolabeled lipids; pharmokinetics of heart/infection imaging. Individual reports are processed separately for the databases

  5. First symposium accelerated partial breast irradiation

    International Nuclear Information System (INIS)

    2012-01-01

    The First symposium accelerated partial breast irradiation, was organized by the Marie Curie Foundation, between the 14 to 16 june 2012, in the Cordoba city of Argentina. In this event were presented some papers on the following topics: radiotherapy in breast cancer; interaction between systemic treatments and radiotherapy; interstitial brachytherapy.

  6. Culinary Arts Hospitality Symposium Planning Guide.

    Science.gov (United States)

    Borgie, Karen; Wang, Yeimei

    This guide was developed as part of a project to standardize California's statewide culinary arts curriculum based on industry guidelines and standards. It details a process that California community colleges can use to plan a hospitality symposium that will accomplish the following objectives: provide students with a forum to demonstrate their…

  7. EDITORIAL: Proceedings of the 7th International LISA Symposium, Barcelona, Spain, 16-20 June 2008 Proceedings of the 7th International LISA Symposium, Barcelona, Spain, 16-20 June 2008

    Science.gov (United States)

    Lobo, Alberto; Sopuerta, Carlos F.

    2009-05-01

    In June 2006 the LISA International Science Team (LIST) accepted the bid presented by the Institut d'Estudis Espacials de Catalunya (IEEC) to host the 7th International LISA Symposium. This was during its 11th meeting at the University of Maryland, just before the 6th edition of the symposium started at NASA's Goddard Space Flight Center. The 7th International LISA Symposium took place in the city of Barcelona, Spain, 16-20 June, 2008, in the premises of CosmoCaixa, a modern science museum located in the hills near Tibidabo. Almost 240 delegates registered for the event, a record breaking figure compared to previous editions of the symposium. Many of the most renowned world experts in LISA, gravitational wave science, and astronomy, as well as engineers, attended LISA #7 and produced state of the art presentations, while everybody benefited from the opportunity to have live discussions during the week in a friendly environment. The programme included 31 invited plenary lectures in the mornings, and eight parallel sessions in the afternoons. These were classified into seven major areas of research: LISA Technology, LISA PathFinder, LISA PathFinder Data Analysis, LISA Data Analysis, Gravitational Wave Sources, Cosmology and Fundamental Physics with LISA and Other Gravitational Wave Detectors. Abstracts for 138 communications were received, from which a selection was made by the session convenors which would fit time constraints. Up to 63 posters completed the scientific programme. More details on the programme, including some of the talks, can be found at the symposium website:http://www.ice.cat/research/LISA_Symposium. There was, however, a remarkable add-on: Professor Clifford Will delivered a startling presentation to the general public, who completely filled the Auditori—the main conference room, 320 seats—and were invited to ask questions to the speaker who boldly guided them through the daunting world of Black Holes, Waves of Gravity, and other Warped Ideas

  8. EREM 2001 - 3. symposium and status report on electrokinetic remediation

    Energy Technology Data Exchange (ETDEWEB)

    Czurda, C.; Haus, R. (eds.); Hoetzl, H.

    2001-07-01

    Papers have been submitted by authors from around the world, reflecting the worldwide interest in electrokinetic remediation techniques. Therefore the symposium series plays a significant role in the presentation of recent advancements in electrochemical decontamination of polluted sediments on both scientific and technical level. In the field of potential cost-saving, innovative in-situ remediation technologies electrokinetics are already identified throughout the world. The main topics of the symposium are: electrokinetic models, electrokinetic transport processes, technical installation, combination of electroremediation with different remediation methods and the application in various electrokinetic field test demonstrations.

  9. Proceedings of the 1st symposium on advanced science research

    International Nuclear Information System (INIS)

    1995-09-01

    The 1st symposium on advanced science research was held in Tokai-mura, Ibaraki-ken, on 23-24 March, 1995, under the auspices of JAERI. Two hundred and sixty scientists attended the symposium; over 40% of the attendants were from universities and laboratories outside JAERI. This proceedings consists of 6 oral presentations of the research activities in the Advanced Science Research Center, 70 poster presentations on the field of basic science from both the inside and outside of JAERI and 2 panel discussions on the actinide physics and biocrystallography. (author)

  10. 3S'83 Symposium on surface science. Contributions

    International Nuclear Information System (INIS)

    Braun, P.; Betz, G.; Husinsky, W.; Soellner, E.; Stoeri, H.; Varga, P.

    1983-01-01

    This symposium included the topics: electronic structure; ion-surface-interaction; surface structure; adsorption and reactivity; surface analysis; 60 papers were presented, only part of which pertain to INIS. (G.Q.)

  11. Life cycle assessment of products and technologies. LCA Symposium

    Energy Technology Data Exchange (ETDEWEB)

    Koukkari, H.; Nors, M. (eds.)

    2009-12-15

    VTT Technical Research Centre of Finland organised a Symposium 'Life Cycle Assessment of Products and Technologies' on the 6th of October, 2009. The Symposium gave a good overview of methods, tools and applications of Life Cycle Assessment developed and utilised in several technology fields of VTT. The 12 Symposium papers deal with recent LCA studies on products and technologies. The scope ranges from beverage cups to urban planning, from inventory databases to rating systems. Topical issues relating to climate change concern biorefineries and the overall impacts of the utilisation of biomass. The calculation of carbon footprints is also introduced through paper products and magazines. One example of LCA tools developed at VTT addresses cement manufacturing. VTT's transport emission database, LIPASTO, was introduced in detail. The use of LCA methods and life cycle thinking is described in various contexts: product development in relation to precision instruments; selection of materials and work processes in relation to sediment remediation project; and procedures of sustainability rating through VTT's office building Digitalo. The Climate Bonus project presented a demonstrated ICT support that informs about the greenhouse gas emissions and carbon footprints of households. (orig.)

  12. The notochord breaks bilateral symmetry by controlling cell shapes in the zebrafish laterality organ.

    Science.gov (United States)

    Compagnon, Julien; Barone, Vanessa; Rajshekar, Srivarsha; Kottmeier, Rita; Pranjic-Ferscha, Kornelija; Behrndt, Martin; Heisenberg, Carl-Philipp

    2014-12-22

    Kupffer's vesicle (KV) is the zebrafish organ of laterality, patterning the embryo along its left-right (LR) axis. Regional differences in cell shape within the lumen-lining KV epithelium are essential for its LR patterning function. However, the processes by which KV cells acquire their characteristic shapes are largely unknown. Here, we show that the notochord induces regional differences in cell shape within KV by triggering extracellular matrix (ECM) accumulation adjacent to anterior-dorsal (AD) regions of KV. This localized ECM deposition restricts apical expansion of lumen-lining epithelial cells in AD regions of KV during lumen growth. Our study provides mechanistic insight into the processes by which KV translates global embryonic patterning into regional cell shape differences required for its LR symmetry-breaking function. Copyright © 2014 Elsevier Inc. All rights reserved.

  13. Proceedings of the 2006 symposium on nuclear data

    International Nuclear Information System (INIS)

    Hazama, Taira; Fukahori, Tokio

    2008-09-01

    The 2006 Symposium on Nuclear Data was held at RICOTTI at Tokai-mura, Ibaraki-ken, Japan, on 25th and 26th of January 2007, with about 80 participants. Nuclear Data Division of Atomic Energy Society of Japan organized this symposium with cooperation of North Kanto Branch of the society. In the oral sessions, presented were 6 papers on topics of nuclear data needs for the fission reactor developments and non-energy nuclear applications. In the poster session, presented were 16 papers concerning experiments, evaluations, benchmark tests, applications, and so on. Tutorials on nuclear data, which were for uses of covariance data and MVP code, were also done. Major part of those presented papers is compiled in this proceedings. (author)

  14. Gamma-Ray Bursts: 4th Huntsville Symposium. Proceedings

    International Nuclear Information System (INIS)

    Meegan, C.A.; Preece, R.D.; Koshut, T.M.

    1998-01-01

    These proceedings represent papers presented at the Fourth Huntsville Gamma-Ray Bursts Symposium held in September, 1997 in Huntsville, Alabama, USA. This conference occurred at a crucial time in the history of the gamma-ray burst research. In early 1997, 30 years after the detection of the first gamma-ray burst by the Vela satellites, counterparts to bursts were finally detected at optical and radio wavelengths. The symposium attracted about 200 scientists from 16 countries. Some of the topics discussed include gamma-ray burst spectra, x-ray observations, optical observations, radio observations, host galaxies, shocks and afterglows and models of gamma-ray bursts. There were 183 papers presented, out of these, 16 have been abstracted for the Energy Science and Technology database

  15. Proceedings of the 1991 symposium on nuclear data

    Energy Technology Data Exchange (ETDEWEB)

    Baba, Mamoru [Tokyo Univ. (Japan); Nakagawa, Tsuneo [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Japanese Nuclear Data Committee

    1992-03-15

    The 1991 Symposium on Nuclear data was held at Tokai Research Establishment, Japan Atomic Energy Research Institute (JAERI), on 28th and 29th of November 1991. This symposium was organized by Japanese Nuclear Data Committee and Nuclear Data Center, JAERI. In the oral session, presented were 15 papers on nuclear data activities in Thailand, status reviews of JENDL-3 and its special purpose files, OMEGA program and ESNIT promoted by JAERI and related nuclear data, reviews of nuclear theories, nuclear data in the intermediate energy region, topics on knowledge technology and reactor physics. In the poster session, twenty-three papers were presented, which were related to nuclear data measurements, benchmark tests of evaluated data and evaluation. All of the 38 papers are compiled in the proceedings.

  16. Report of the international symposium for ITER. 'Burning plasma science and technology on ITER'

    International Nuclear Information System (INIS)

    2002-10-01

    This report contains the presentations on the International Symposium for ITER, held on Jan. 24, 2002 on the occasion of the ITER Governmental Negotiations in Tokyo. This symposium is organized by Japan Atomic Energy Research Institute with the support of the Ministry of Education, Culture, Sports, Science and Technology (MEXT). The meaningful results were obtained through this symposium especially on new frontiers of science and technology brought by ITER, accelerated road maps towards realizing fusion energy, and portfolio of other fusion configurations from ITER. The 5 of the presented papers are indexed individually (J.P.N.)

  17. NIC symposium 2010. Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Muenster, Gernot [Muenster Univ. (Germany). Inst. fuer Theoretische Physik 1; Wolf, Dietrich [Duisburg-Essen Univ., Duisburg (Germany). Fakultaet fuer Physik; Kremer, Manfred (eds.) [Forschungszentrum Juelich GmbH (DE). Juelich Supercomputing Centre (JSC)

    2012-06-21

    The fifth NIC-Symposium gave an overview of the activities of the John von Neumann Institute for Computing (NIC) and of the results obtained in the last two years by research groups supported by the NIC. The large recent progress in supercomputing is highlighted by the fact that the newly installed Blue Gene/P system in Juelich - with a peak performance of 1 Petaflop/s - currently ranks number four in the TOP500 list. This development opens new dimensions in simulation science for researchers in Germany and Europe. NIC - a joint foundation of Forschungszentrum Juelich, Deutsches Elektronen-Synchrotron (DESY) and Gesellschaft fuer Schwerionenforschung (GSI) - supports with its members' supercomputer facilities about 130 research groups at universities and national labs working on computer simulations in various fields of science. Fifteen invited lectures covered selected topics in the following fields: Astrophysics Biophysics Chemistry Elementary Particle Physics Condensed Matter Materials Science Soft Matter Science Environmental Research Hydrodynamics and turbulence Plasma Physics Computer Science The talks are intended to inform a broad audience of scientists and the interested public about the research activities at NIC. The proceedings of the symposium cover projects that have been supported by the IBM supercomputers JUMP and IBM Blue Gene/P in Juelich and the APE topical computer at DESY-Zeuthen in an even wider range than the lectures.

  18. NIC symposium 2010. Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Muenster, Gernot [Muenster Univ. (Germany). Inst. fuer Theoretische Physik 1; Wolf, Dietrich [Duisburg-Essen Univ., Duisburg (Germany). Fakultaet fuer Physik; Kremer, Manfred [Forschungszentrum Juelich GmbH (DE). Juelich Supercomputing Centre (JSC)

    2012-06-21

    The fifth NIC-Symposium gave an overview of the activities of the John von Neumann Institute for Computing (NIC) and of the results obtained in the last two years by research groups supported by the NIC. The large recent progress in supercomputing is highlighted by the fact that the newly installed Blue Gene/P system in Juelich - with a peak performance of 1 Petaflop/s - currently ranks number four in the TOP500 list. This development opens new dimensions in simulation science for researchers in Germany and Europe. NIC - a joint foundation of Forschungszentrum Juelich, Deutsches Elektronen-Synchrotron (DESY) and Gesellschaft fuer Schwerionenforschung (GSI) - supports with its members' supercomputer facilities about 130 research groups at universities and national labs working on computer simulations in various fields of science. Fifteen invited lectures covered selected topics in the following fields: Astrophysics Biophysics Chemistry Elementary Particle Physics Condensed Matter Materials Science Soft Matter Science Environmental Research Hydrodynamics and turbulence Plasma Physics Computer Science The talks are intended to inform a broad audience of scientists and the interested public about the research activities at NIC. The proceedings of the symposium cover projects that have been supported by the IBM supercomputers JUMP and IBM Blue Gene/P in Juelich and the APE topical computer at DESY-Zeuthen in an even wider range than the lectures.

  19. NIC symposium 2010. Proceedings

    International Nuclear Information System (INIS)

    Muenster, Gernot

    2012-01-01

    The fifth NIC-Symposium gave an overview of the activities of the John von Neumann Institute for Computing (NIC) and of the results obtained in the last two years by research groups supported by the NIC. The large recent progress in supercomputing is highlighted by the fact that the newly installed Blue Gene/P system in Juelich - with a peak performance of 1 Petaflop/s - currently ranks number four in the TOP500 list. This development opens new dimensions in simulation science for researchers in Germany and Europe. NIC - a joint foundation of Forschungszentrum Juelich, Deutsches Elektronen-Synchrotron (DESY) and Gesellschaft fuer Schwerionenforschung (GSI) - supports with its members' supercomputer facilities about 130 research groups at universities and national labs working on computer simulations in various fields of science. Fifteen invited lectures covered selected topics in the following fields: Astrophysics Biophysics Chemistry Elementary Particle Physics Condensed Matter Materials Science Soft Matter Science Environmental Research Hydrodynamics and turbulence Plasma Physics Computer Science The talks are intended to inform a broad audience of scientists and the interested public about the research activities at NIC. The proceedings of the symposium cover projects that have been supported by the IBM supercomputers JUMP and IBM Blue Gene/P in Juelich and the APE topical computer at DESY-Zeuthen in an even wider range than the lectures.

  20. Symposium Gyro Technology 1997

    Energy Technology Data Exchange (ETDEWEB)

    Sorg, H [ed.; Stuttgart Univ. (Germany). Inst. A fuer Mechanik

    1997-10-01

    This volume includes the twenty papers which were presented at the Symposium Gyro Technology 1997. The subjects that have been treated during the symposium were as follows: Performance and design of silicon micromachined gyro; improved rate gyroscope designs designated for fabrication by modern deep silicon etching; micromechanical vibratory rate gyroscopes fabricated in conventional CMOS; error modelling of silicon angular rate sensor; a capacitive accelerometer as an example for surface micromachined inertial sensors; initial production results of a new family of fiber optic gyroscopes; dual-axis multiplexed open loop fiber optic gyroscope; flattely supported vibratory gyro-sensor using a Trident-type tuning fork resonator; innovative mechanizations to optimize inertial sensors for high or low rate operations; design of a planar vibratory gyroscope using electrostatic actuation and electromanetic detection; fiber optic gyro based land navigation system; FOG AHRS and AHRS/GPS navigation system: the low cost solution; GPS/GLONASS/INS-navigation (GLOGINAV); small-sized integrated system of the sea mobile objects attitude and navigation; concepts for hybrid positioning; preliminary results from a large ring laser gyroscope for fundamental physics and geophysics; a `sense of balance` - AHRS with low-cost vibrating-gyroscopes for medical diagnostics; application of strapdown inertial systems of orientation and navigation in intrapipe moving diagnostic apparatus; investigation of a digital readout system for laser gyro; the use of angular rate multiple integrals as input signals for strapdown attitude algorithms. (AKF)

  1. International beta-dosimetry symposium. Program and abstracts

    International Nuclear Information System (INIS)

    1983-02-01

    Abstracts of the presentations at the symposium are contained in this volume. Problems associated with beta dosimetry, beta detectors and dosemeters, and current development programs are described. Each abstract has been indexed separately for inclusion in the Energy Data Base

  2. Proceedings of the sixth Asian symposium on research reactors

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-08-01

    The symposium consisted of 16 sessions with 58 submitted papers. Major fields were: (1) status and future plan of research and testing reactors, (2) operating experiences, (3) design and modification of the facility, and reactor fuels, (4) irradiation studies, (5) irradiation facilities, (6) reactor characteristics and instrumentation, and (7) neutron beam utilization. Panel discussion on the 'New Trends on Application of Research and Test Reactors' was also held at the last of the symposium. About 180 people participated from China, Korea, Indonesia, Thailand, Bangladesh, Vietnam, Chinese Taipei, Belgium, France, USA, Japan and IAEA. The 58 of the presented papers are indexed individually. (J.P.N.)

  3. Proceedings of the sixth Asian symposium on research reactors

    International Nuclear Information System (INIS)

    1999-08-01

    The symposium consisted of 16 sessions with 58 submitted papers. Major fields were: 1) status and future plan of research and testing reactors, 2) operating experiences, 3) design and modification of the facility, and reactor fuels, 4) irradiation studies, 5) irradiation facilities, 6) reactor characteristics and instrumentation, and 7) neutron beam utilization. Panel discussion on the 'New Trends on Application of Research and Test Reactors' was also held at the last of the symposium. About 180 people participated from China, Korea, Indonesia, Thailand, Bangladesh, Vietnam, Chinese Taipei, Belgium, France, USA, Japan and IAEA. The 58 of the presented papers are indexed individually. (J.P.N.)

  4. Proceedings of the FAA-NASA symposium on the continued airworthiness of aircraft structures : part 2

    Science.gov (United States)

    1997-07-01

    This publication contains the fifty-two technical papers presented at the FAA-NASA Symposium on the Continued Airworthiness of Aircraft Structures. The symposium, hosted by the FAA Center of Excellence for Computational Modeling of : Aircraft Structu...

  5. Proceedings of the FAA-NASA symposium on the continued airworthiness of aircraft structures : part 1

    Science.gov (United States)

    1997-07-01

    This publication contains the fifty-two technical papers presented at the FAA-NASA Symposium on the Continued Airworthiness of Aircraft Structures. The symposium, hosted by the FAA Center of Excellence for Computational Modeling of : Aircraft Structu...

  6. *Abstracts - 7th IN-CAM Research Symposium, Evaluating CAM Practices: Effectiveness, Integration, Economics & Safety - November 2012.

    Science.gov (United States)

    Boon, Heather; Verhoef, Marja J

    2012-10-23

    Abstract The following are abstracts of oral and poster presentations given at the 7th IN-CAM Research Symposium - Evaluating CAM Practices: Effectiveness, Integration, Economics & Safety, and the 4th HomeoNet Research Forum, a pre-Symposium event. The IN-CAM Research Symposium was held November 2 to 4, 2012 at the Leslie Dan Faculty of Pharmacy, University of Toronto, in Toronto, Ontario, Canada. For more information, please visit: www.incamresearch.ca.

  7. Sixth underground coal-conversion symposium

    Energy Technology Data Exchange (ETDEWEB)

    1980-01-01

    The sixth annual underground coal conversion symposium was held at Shangri-la near Afton, Oklahoma, July 13 to 17, 1980. Sessions were developed to: Doe Field Programs, Major Industry Activity, Mathematical Modeling, Laboratory Studies, Environmental Studies, Economics, Instruments and Controls, and General Topics. Fifty-two papers from the proceedings have been entered individually into EDB and ERA. Thirteen papers had been entered previously from other sources. (LTN)

  8. ICRP 2015. International symposium on the radiation protection system. Report and reflection on a significant symposium; ICRP 2015. 3. Internationales Symposium zum System des Strahlenschutzes. Bericht und Reflexion ueber ein bedeutsames Symposium

    Energy Technology Data Exchange (ETDEWEB)

    Lorenz, Bernd

    2016-08-01

    The ICRP international symposium on the radiation protection system provides always extensive information on new developments in radiation protection. The ICRP 2105 discussed the following issues: radiation effects of low dose irradiation, dose coefficients for internal and external exposures, radiation protection in nuclear medicine, application of ICRP recommendations, environmental protection, studies on existing exposure situations, medical radiation protection today, science behind radiation doses, new developments in radiation effects, and ethics in radiation protection.

  9. Proceedings of the third symposium on science of hadrons under extreme conditions

    Energy Technology Data Exchange (ETDEWEB)

    Chiba, Satoshi (ed.) [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2001-09-01

    The third symposium on Science of Hadrons under Extreme Conditions, organized by the Research Group for Hadron Science, Advanced Science Research Center, was held at Tokai Research Establishment of JAERI on January 29 to 31, 2001. The symposium was devoted for discussions and presentations of research results in wide variety of hadron physics such as nuclear matter, high-energy nuclear reactions, quantum chromodynamics, neutron stars, supernovae, nucleosynthesis as well as finite nuclei to understand various aspects of hadrons under extreme conditions. Twenty two papers on these topics presented at the symposium, including a special talk on the present status of JAERI-KEK joint project on high-intensity proton accelerator, aroused lively discussions among approximately 40 participants. The 20 of the presented papers are indexed individually. (J.P.N.)

  10. Developments in caries diagnosis and their relationship to treatment decisions and quality of care - ORCA Saturday Afternoon Symposium 1997

    NARCIS (Netherlands)

    Verdonschot, EH; Angmar-Mansson, B; ten Bosch, J.J.; Deery, CH; Huysmans, MCDNJM; Pitts, NB; Waller, E

    1999-01-01

    This symposium report evaluates the achievements made in caries diagnostic research since the previous symposium held in 1992. The symposium aimed at presenting the state of the art of caries diagnostic methods, on presenting the links between caries diagnosis and subsequent treatment decisions and

  11. Restoration of environments with radioactive residues. Papers and discussions. Proceedings of an international symposium

    International Nuclear Information System (INIS)

    2000-01-01

    After the use of radioactive substances or the application of nuclear energy, radioactive residues may remain in the environment and may give rise to radiation exposure of people. Radioactive residues can originate from several sources. They may be remnants following the termination of a practice such as the decommissioning of a nuclear power plant. Occasionally, residues can derive from the accumulation of radionuclides from normal discharges to the environment of radioactive effluents from practices. Most commonly, they are the result of human activities that have been performed in the past without proper regard for the current international radiation protection requirements. They can also be the consequence of accidents that have released radioactive material to the environment. Radioactive residues are also generated by nature, e.g. in natural deposits of radioactive material found in the earth. Spring waters convey these materials. No matter what the cause of radioactive residues may be, there is the question of whether any restoration of the affected environment is required and, if so, to what extent it should be performed. The International Symposium on Restoration of Environments with Radioactive Residues was devoted to discussing these questions and to fostering the exchange of information on this subject. The Symposium explored five main topics: global overview of the problem; restoration principles and criteria; case studies of actual radiological assessments; a critical analysis of the case studies; and the role of public participation in the decision aiding and decision making processes. The Programme Committee of the Symposium accepted a number of contributed papers and posters for consideration at the Symposium, and these were published shortly before the Symposium. In early 2000, the IAEA released as Working Material a draft, unedited compilation of the present Proceedings Series publication. The present publication, which constitutes the record of

  12. Proceedings of the first energy research power supercomputer users symposium

    International Nuclear Information System (INIS)

    1991-01-01

    The Energy Research Power Supercomputer Users Symposium was arranged to showcase the richness of science that has been pursued and accomplished in this program through the use of supercomputers and now high performance parallel computers over the last year: this report is the collection of the presentations given at the Symposium. ''Power users'' were invited by the ER Supercomputer Access Committee to show that the use of these computational tools and the associated data communications network, ESNet, go beyond merely speeding up computations. Today the work often directly contributes to the advancement of the conceptual developments in their fields and the computational and network resources form the very infrastructure of today's science. The Symposium also provided an opportunity, which is rare in this day of network access to computing resources, for the invited users to compare and discuss their techniques and approaches with those used in other ER disciplines. The significance of new parallel architectures was highlighted by the interesting evening talk given by Dr. Stephen Orszag of Princeton University

  13. International Symposium on Dynamics of Ordering Processes in Condensed Matter

    CERN Document Server

    Furukawa, H

    1988-01-01

    The International Symposium on Dynamics of Ordering Processes in Condensed Matter was held at the Kansai Seminar House, Kyoto, for four days, from 27 to 30 August 1987, under the auspices of the Physical Soci­ ety of Japan. The symposium was financially supported by the four orga­ nizations and 45 companies listed on other pages in this volume. We are very grateful to all of them and particularly to the greatest sponsor, the Commemorative Association for the Japan World Exposition 1970. A total Df 22 invited lectures and 48 poster presentations were given and 110 participants attended from seven nations. An objective of the Symposium was to review and extend our present understanding of the dynamics of ordering processes in condensed matters, (for example, alloys, polymers and fluids), that are brought to an un­ stable state by sudden change of such external parameters as temperature and pressure. A second objective, no less important, was to identify new fields of science that might be investigated by sim...

  14. Proceedings of radiation and occupational health Symposium

    International Nuclear Information System (INIS)

    Ng Kwan Hoong

    1995-07-01

    This book compiled the papers presented at this symposium. The were papers on policy of radiation safety regulations, radiation safety measures, radiation in medicine and radiation protection, radiation measurements, radon measurement, radiation in petroleum industry, radiation monitoring and non ionizing radiation safety

  15. 8. European sewage and refuse symposium. Documentation

    International Nuclear Information System (INIS)

    1990-01-01

    The subject of the 8. European Sewage and Refuse Symposium is covered under the following headings: collection and control in sewers, industrial waste water management, pretreatment, combined treatment, special cases, industrial waste water sludges disposal and the European waste business. (orig./BBR)

  16. Highlights of the heavy ion fusion symposium

    International Nuclear Information System (INIS)

    Keefe, D.

    1986-01-01

    The current status and prospects for inertial confinement fusion based on the use of intense beams of heavy ions will be described in the light of results presented at the International Symposium on Heavy Ion Fusion, (Washington, DC, May 27-29, 1986)

  17. Highlights of the heavy ion fusion symposium

    International Nuclear Information System (INIS)

    Keefe, D.

    1986-07-01

    The current status and prospects for inertial confinement fusion based on the use of intense beams of heavy ions will be described in the light of results presented at the International Symposium on Heavy Ion Fusion, (Washington, DC, May 27-29, 1986)

  18. PREFACE: 12th Russia/CIS/Baltic/Japan Symposium on Ferroelectricity and 9th International Conference on Functional Materials and Nanotechnologies (RCBJSF-2014-FM&NT)

    Science.gov (United States)

    Sternberg, Andris; Grinberga, Liga; Sarakovskis, Anatolijs; Rutkis, Martins

    2015-03-01

    The joint International Symposium RCBJSF-2014-FM&NT successfully has united two international events - 12th Russia/CIS/Baltic/Japan Symposium on Ferroelectricity (RCBJSF-12) and 9th International Conference Functional Materials and Nanotechnologies (FM&NT-2014). The RCBJSF symposium is a continuation of series of meetings on ferroelectricity, the first of which took place in Novosibirsk (USSR) in 1976. FM&NT conferences started in 2006 and have been organized by Institute of Solid State Physics, University of Latvia in Riga. In 2012 the International program committee decided to transform this conference into a traveling Baltic State conference and the FM&NT-2013 was organized by the Institute of Physics, University of Tartu, Estonia. In 2014 the joint international symposium RCBJSF-2014-FM&NT was organized by the Institute of Solid State Physics, University of Latvia and was part of Riga - 2014, the European Capital of Culture event. The purpose of the joint Symposium was to bring together scientists, students and high-level experts in solid state physics, materials science, engineering and related disciplines. The number of the registered participants from 26 countries was over 350. During the Symposium 128 high quality scientific talks (5 plenary, 42 invited, 81 oral) and over 215 posters were presented. All presentations were divided into 4 parallel sessions according to 4 main topics of the Symposium: Ferroelectricity, including ferroelectrics and multiferroics, pyroelectrics, piezoelectrics and actuators, integrated ferroelectrics, relaxors, phase transitions and critical phenomena. Multifunctional Materials, including theory, multiscale and multiphenomenal material modeling and simulation, advanced inorganic, organic and hybrid materials. Nanotechnologies, including progressive methods, technologies and design for production, investigation of nano- particles, composites, structures, thin films and coatings. Energy, including perspective materials and

  19. 29th International Symposium on Shock Waves

    CERN Document Server

    Ranjan, Devesh

    2015-01-01

    This proceedings present the results of the 29th International Symposium on Shock Waves (ISSW29) which was held in Madison, Wisconsin, U.S.A., from July 14 to July 19, 2013. It was organized by the Wisconsin Shock Tube Laboratory, which is part of the College of Engineering of the University of Wisconsin-Madison. The ISSW29 focused on the following areas: Blast Waves, Chemically Reactive Flows, Detonation and Combustion,  Facilities, Flow Visualization, Hypersonic Flow, Ignition, Impact and Compaction, Industrial Applications, Magnetohydrodynamics, Medical and Biological Applications, Nozzle Flow, Numerical Methods, Plasmas, Propulsion, Richtmyer-Meshkov Instability, Shock-Boundary Layer Interaction, Shock Propagation and Reflection, Shock Vortex Interaction, Shock Waves in Condensed Matter, Shock Waves in Multiphase Flow, as well as Shock Waves in Rarefield Flow. The two Volumes contain the papers presented at the symposium and serve as a reference for the participants of the ISSW 29 and individuals interes...

  20. 2014 ICSA/KISS Joint Applied Statistics Symposium

    CERN Document Server

    Liu, Mengling; Luo, Xiaolong

    2016-01-01

    The papers in this volume represent the most timely and advanced contributions to the 2014 Joint Applied Statistics Symposium of the International Chinese Statistical Association (ICSA) and the Korean International Statistical Society (KISS), held in Portland, Oregon. The contributions cover new developments in statistical modeling and clinical research: including model development, model checking, and innovative clinical trial design and analysis. Each paper was peer-reviewed by at least two referees and also by an editor. The conference was attended by over 400 participants from academia, industry, and government agencies around the world, including from North America, Asia, and Europe. It offered 3 keynote speeches, 7 short courses, 76 parallel scientific sessions, student paper sessions, and social events. The most timely and advanced contributions from the joint 2014 ICSA/KISS Applied Statistics Symposium All papers feature original, peer-reviewed content Coverage consists of new developments in statisti...