Určování a diagnostika beta-hemolytických streptokoků v klinické mikrobiologii

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VOŘÍŠKOVÁ, Martina

2008-01-01

The genus of Streptococcus includes gram-positive catalase of negative coccus, which rank into pairs and chains and their colonies are also sometimes very small in enriched soils. Most of species are selectively anaerobic. This genus includes a large number of species with different significance for people ´s disorders, and also the species significant for veterinary medicine. Beta-hemolytic or pyogenic Streptococci important in human medicine include first of all streptococci of A and B grou...

Diagnostika psychosociálního klimatu porodnice – konstrukce a psychometrická evaluace dotazníku KLI-P

Czech Academy of Sciences Publication Activity Database

Takács, L.; Smolík, Filip; Sněhotová, J.; Horáková Hoskovcová, S.

2013-01-01

Roč. 57, č. 1 (2013), s. 73-91 ISSN 0009-062X Institutional research plan: CEZ:AV0Z7025918 Institutional support: RVO:68081740 Keywords : psychosocial climate * maternity hospital * evaluation of health care Subject RIV: AN - Psychology Impact factor: 0.292, year: 2013

Diagnostika rané slovní zásoby rodičovskými dotazníky: přehled a pilotní studie

Czech Academy of Sciences Publication Activity Database

Votavová, K.; Smolík, Filip

2010-01-01

Roč. 54, č. 3 (2010), s. 301-313 ISSN 0009-062X R&D Projects: GA AV ČR KJB700250801 Institutional research plan: CEZ:AV0Z70250504 Keywords : language acquisition * lexical development * parent report Subject RIV: AN - Psychology Impact factor: 0.230, year: 2010

Differential phenotyping of Brucella species using a newly developed semi-automated metabolic system

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Appel Bernd

2010-10-01

Full Text Available Abstract Background A commercial biotyping system (Taxa Profile™, Merlin Diagnostika testing the metabolization of various substrates by bacteria was used to determine if a set of phenotypic features will allow the identification of members of the genus Brucella and their differentiation into species and biovars. Results A total of 191 different amines, amides, amino acids, other organic acids and heterocyclic and aromatic substrates (Taxa Profile™ A, 191 different mono-, di-, tri- and polysaccharides and sugar derivates (Taxa Profile™ C and 95 amino peptidase- and protease-reactions, 76 glycosidase-, phosphatase- and other esterase-reactions, and 17 classic reactions (Taxa Profile™ E were tested with the 23 reference strains representing the currently known species and biovars of Brucella and a collection of 60 field isolates. Based on specific and stable reactions a 96-well "Brucella identification and typing" plate (Micronaut™ was designed and re-tested in 113 Brucella isolates and a couple of closely related bacteria. Brucella species and biovars revealed characteristic metabolic profiles and each strain showed an individual pattern. Due to their typical metabolic profiles a differentiation of Brucella isolates to the species level could be achieved. The separation of B. canis from B. suis bv 3, however, failed. At the biovar level, B. abortus bv 4, 5, 7 and B. suis bv 1-5 could be discriminated with a specificity of 100%. B. melitensis isolates clustered in a very homogenous group and could not be resolved according to their assigned biovars. Conclusions The comprehensive testing of metabolic activity allows cluster analysis within the genus Brucella. The biotyping system developed for the identification of Brucella and differentiation of its species and biovars may replace or at least complement time-consuming tube testing especially in case of atypical strains. An easy to handle identification software facilitates the

All-union symposium on radiodiagnosis and radiotherapy of malignant neoplasms in children; Luchevaya diagnostika i luchevaya terapiya zlokachestvennykh novoobrazovanij u detej. Materialy Vsesoyuznogo simposiuma

Energy Technology Data Exchange (ETDEWEB)

Tsyb, A F; Durnov, L A [eds.

1990-07-01

This volume contains the proceedings of the All-Union Symposium on Radcodiagnosis and Radiotherapy of Malignant Neoplasms in Children held in Obnisk, Russian SFSR May 10-11, 1990. Individual papers were prepared for the database.

Prenatal diagnostics of congenital malformations, the most efficient way to decrease genetic consequences of Chernobyl accident; Perinatal'naya diagnostika vrozhdennykh porokov razvitiya - naibolee ehffektivnyj metod minimizatsii geneticheskikh posledstvij Chernobyl'skoj katastrofy

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Lazjuk, G I; Zatsepin, I O; Kravchuk, Zn P; Khmel, R D

2003-04-01

Long-term study of the prevalence of congenital malformations (CM) in the population of Belarus, carried out by Belarus Institute for Hereditary Diseases, showed considerably increased, from 5.6% in 1980-1985 to 7.2% in 1986-1996, frequency of the anomalies found in embryos, increased number of malformations in induced abortuses and also the growth of CM in newborns, from 5 in 1983-1985 to 7.2 in 2001, in post-Chernobyl period. The highest raise was registered in the mostly contaminated with Cs-137 areas in the first post-Chernobyl years. There are various reasons for the observed increase, but they are still not clearly understood. Nutrition imbalance (deficit of vitamins, essential amino acids and soluble selenium), physoemotional stress, hormone imbalance, alcoholism and increased level of mutations due to additional exposure of the gonads of the residents of contaminated areas of the Republic can have some impact. Positive prevalence trend of multifactorial anomalies evidences multifactorial origin of the increased prevalence of embryonal anomalies. Both, increased prevalence of CM with great contribution of dominant mutations and the peak of Down's syndrome cases, recorded in January, 1987 with maximum in Gomel region, suggest mutation component. At present, the most efficient measures to prevent the birth of malformed children are prenatal diagnostics and vitamin supplement of the couples, who plan their pregnancy, and pregnant women in the first trimester. According to the conclusion, made by WHO experts, vitamin intake can considerably reduce many CM with multifactorial origin. Positive results can be achieved only if the problem is solved by the government, when vitamins are added to flour, cereals and bread. Prenatal diagnostics with subsequent termination of pregnancy, where incurable anomalies are found, contributes greatly to the reduction of the proportion of malformed newborns, irrespective of the factors, which caused the anomalies. Thus, in Belarus in the last 5 years about 500 pregnancies were terminated annually for genetic reasons. Over 100 pregnancies were terminated in Gomel region, which considerably reduced (by 1-3%) perinatal mortality, children's morbidity and disability. The number of children, born with the anomalies of the central nervous system, renal polycystosis and agenesis, omphalocele, reduction limb defects, is decreasing most considerably. The potentialities of prenatal diagnostics of CM are far from being used adequately in the Republic. With sufficient financing, present-day techniques allow prenatal diagnosing of 1000 cases instead of 600 diagnosed each year. The program will be productive, if prenatal biochemical screening and invasive prenatal procedures are financed regularly and interregional centres for prenatal diagnostics are created. These measures will not only reduce the proportion of children, born with congenital malformations, but increase the birth rate in Belarus, since the future mothers will not be scared to give birth to a malformed child, which is especially essential for the population exposed to radiation due to Chernobyl accident (authors)

Diagnostika stavu nosné konstrukce a následná sanační opatření při opravách dřevěných krytých mostů a lávek

Czech Academy of Sciences Publication Activity Database

Bláha, Jiří; Hunková, V.; Kloiber, Michal

2008-01-01

Roč. 4, č. 7 (2008), s. 66-69 ISSN 1336-7617 Grant - others:GA ČR(CZ) GA103/07/1091 Program:GA Institutional research plan: CEZ:AV0Z20710524 Keywords : Footbridges * bridges * diagnostics * wood Subject RIV: JN - Civil Engineering

Diagnosis of Massive Pulmonary Embolism in Man by Radioisotope Scanning; Diagnostic par Scintigraphy de l'Embolie Pulmonaire Massive chez l'Homme; Diagnostika massivnoj legochnoj ehmbolii u cheloveka s pomoshch'yu radioizotopnogo skennirovaniya; Diagnostico de la Embolia Pulmonar Masiva en el Hombre por Exploracion Radioisotopica

Energy Technology Data Exchange (ETDEWEB)

Wagner, Jr., H. N.; Sabiston, Jr., D. C.; Iio, M.; Langan, J. K. [Departments of Medicine, Surgery and Radiology, Johns Hopkins University School of Medicine, Baltimore, MD (United States)

1964-10-15

Macroaggregated human-serum albumin particles labelled with either I{sup 131} or chromium-51 have been utilized to determine regional blood flow to the lungs in dogs and man. Following intravenous injection, the particles accumulated in the lung, permitting clear delineation of the lung fields by scintillation scanning. In patients with lung abscess, pneumonia, atelectasis, tumours and thromboembolic disease of the lung, there was a decreased accumulation of the radioactivity in the regions of the lungs involved. The technique was found to be clinically useful in the diagnosis of massive pulmonary emboli in man and in the demonstration of vascular occlusion in certain patients with cor pulmonale. Studies in dogs made possible the determination of the rate at which revascularization occurred following experimental pulmonary emboli. Scintillation scanning was carried out at various times after the removal of the experimental emboli. The circulation was restored through the lungs within a period of several weeks after the removal of chronic pulmonary emboli in dogs. Although aggregated human-serum albumin retained its antigenicity in rabbits, guinea pigs and dogs, extensive studies failed to reveal any antigenicity of the particles to man. Because of the rapid metabolism of the macroaggregated albumin particles, the radiation to the patient was well within permissible levels. The use of albumin of high specific activity permitted injections of small chemical quantities; consequently no cardiovascular effects, such as increases in pulmonary artery pressure, changes in electrocardiogram or respiratory rate, were noted. (author) [French] Pour determiner chez le chien et chez l'homme le flux sanguin vers les poumons, on a utilise des macroparticules d'albumine de serum humain marquee avec {sup 131}I ou {sup 51}Cr. A la suite d'une injection intraveineuse, les particules s'accumulaient dans les poumons, permettant ainsi de delimiter nettement les regions pulmonaires par scintigraphie. Chez les sujets atteints d'abces pulmonaires, de pneumonie, d'atelectasie, de tumeurs ou dethrombo- embolie des poumons, on observait une accumulation moins intense de la radioactivite dans les regions pulmonaires affectees. Du point de vue clinique, cette methode s'est revelee utile pour le diagnostic des embolies pulmonaires massives chez l'homme et pour la mise en evidence d'une occlusion vasculaire chez certains sujets atteints de coeur pulmonaire. Les etudes sur des chiens ont permis de determiner le rythme auquel une vascularisation nouvelle se produisait a la suite d'embolies pulmonaires induites. On a fait des scintigraphies a diverses reprises apres embolectomie. Chez les chiens, la circulation dans les poumons etait retablie dans les quelques semaines qui suivaient l'embolectomie. Si les macroparticules d'albumine de serum humain gardaient leur caractere antigene chez les lapins, les cobayes et les chiens, des etudes tres poussees n'ont pu deceler un tel caractere chez l'homme. Par suite du metabolisme rapide des macroparticules d'albumine, la dose de radioactivite recue par les sujets restait bien en deca des niveaux admissibles. L'emploi d'albumine a forte activite specifique permettait de faire des injections de petites quantites de produit chimique; de ce fait, on n'a pas releve d'effets cardio-vasculaires, tels que des augmentations de la tension dans l'artere pulmonaire, des modifications de l'electro-cardiogramme ou du rythme respiratoire, etc. (author) [Spanish] Los autores utilizaron macroagregados de particulas de seroalbumina humana marcada con {sup 131}I o con {sup 51}Cr para determinar el caudal sanguineo regional que afluye a los pulmones en el perro y en el hombre. Inyectadas por via intravenosa, las particulas se acumulan en el pulmon y permiten delinear claramente los campos pulmonares por exploracion centelleografica. En pacientes con absceso del pulmon, neumonia, atelectasia, tumores y tromboembolias pulmonares, se observo una acumulacion disminuida de radiactividad en las regiones afectadas. Se comprobo la utilidad clinica de esta tecnica para diagnosticar embolias pulmonares masivas en el hombre y para descubrir oclusiones vasculares en ciertos pacientes afectados de cor pulmonale. Los estudios en perros permitieron determinar la rapidez con que progresa la revascularizacion despues de una embolia pulmonar experimental. Se efectuaron varias exploraciones centelleograficas una vez retirados los embolos experimentales. La circulacion se restablecio en todo el pulmon algunas semanas despues de haber eliminado los embolos pulmonares cronicos en los perros. Los agregados de seroalbumina humana han conservado su poder antigenico en los conejos, los cobayos y los perros, pero los estudios realizados no han permitido comprobar que las particulas tengan poder antigenico alguno en el hombre. Gracias al rapido metabolismo de los macroagregados, la dosis de radiacion recibida por el paciente se mantiene bastante inferior a los valores admisibles. El empleo de albuminas de elevada actividad especifica permite limitar considerablemente las cantidades inyectadas; no se observan, por lo tanto, efectos cardiovasculares tales como aumentos de presion en la arteria pulmonar, ni alteraciones del electrocardiograma o del ritmo respiratorio. (author) [Russian] Krupnye chasticy al'bumina syvorotki cheloveka, mechennye jodom-131 ili hromom-51, ispol'zovalis' dlja opredelenija regional'nogo toka krovi v legkih u sobak i cheloveka. Posle vnutrivennogo vvedenija chasticy, nakaplivajushhiesja v legkih, dajut chetkoe izobrazhenie konturov legkih pri scintilljacionnom skenniro- vanii. U pacientov s legochnymi abscessami, pnevmoniej, atelektazom, rakom legkih i trombojembolicheskoj bolezn'ju legkih nabljudalos' ponizhenie nakoplenija radioaktivnosti v porazhennyh uchastkah. Byl najden metod, kotoryj budet prigoden v klinike dlja diagnostiki massivnoj legochnoj jembolii u cheloveka i demonstracii zakuporki sosudov u nekotoryh pacientov s ''cor pulmonale''. Issledovanija na sobakah sdelali vozmozhnym opredelenie skorosti revaskuljarizacii posle jeksperimental'noj legochnoj jembolii. Scintilljacionnoe skennirovanie provodilos' v razlichnye periody vremeni posle udalenija jeksperimental'nogo jembola. Cirkuljacija krovi v legkih u sobak vosstanavlivalas' v techenie neskol'kih nedel' posle udalenija hronicheskogo legochnogo jembola. Hotja krupnye chasticy al'bumina syvorotki cheloveka sohranjali svoi antigennye svojstva dlja krolikov, morskih svinok i sobak, shirokie issledovanija ne priveli k obnaruzheniju kakih-libo antigennyh svojstv jetih chastic dlja cheloveka. Vvidu bystrogo metabolizma krupnyh chastic al'bumina doza obluchenija pacienta nahodilas' v predelah dopustimyh doz. Ispol'zovanie al'bumina s vysokoj udel'noj aktivnost'ju pozvoljalo vvodit' nebol'shie himicheskie kolichestva; vposledstvii ne otmecheno kakih-libo izmenenij so storony serdechno-sosudistoj sistemy, kak povyshenija davlenija v legochnoj arterii, izmenenija jelektrokardiogrammy ili chastoty dyhanija.

Bone mineral density and accelerometer-determined habitual physical activity and inactivity in postmenopausal women [Kostní denzita a habituální pohybová aktivita a inaktivita u postmenopauzálních žen

Directory of Open Access Journals (Sweden)

Ondřej Kapuš

2011-09-01

ální femorální denzitou a ženami s osteopenií. METODIKA: Z 92 žen, jejichž výsledky byly zahrnuty do této studie, bylo v pásmu normálních hodnot T-skóre proximálního femuru 72,8 % žen a u 27,2 % žen dosahovaly hodnoty T-skóre osteopenie. Denzitometrické vyšetření proximálního femuru, stejně tak diagnostika vybraných tělesných složek, byla uskutečněna metodou duální rentgenové absorpciometrie (DXA. Sedmidenní pohybová aktivita byla monitorována pomocí přístroje ActiGraph GT1M. Údaje o denních aktivitách a inaktivitách a času, kdy byl přístroj nošen, byly probandy zapisovány do speciálních záznamových archů. VÝSLEDKY: Ženy s normální femorální denzitou byly celkově pohybově aktivnější než ženy s osteopenií, avšak ženy s osteopenií strávily signifikantně více času aktivitou spojenou s domácností. Z analýzy pohybové inaktivity vyplynulo, že ženy s osteopenií strávily sezením (při čtení, luštění křížovek apod. signifikantně více času ne�� ženy s normální kostní denzitou. ZÁVĚRY: Výsledky této studie prokázaly rozdíly v pohybové aktivitě a inaktivitě mezi ženami s rozdílnou femorální denzitou.

Rozbor morfologie nohy u chlapců a dívek ve věku Infans 2 a Juvenis Analysis of morphology of foot in Moravian male and female students in the age Infans 2 and Juvenis

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Michaela Peštuková

2005-02-01

Full Text Available U 106 studentů a 162 studentek z Gymnázia ve Šternberku a Střední integrované školy v Ostravě ve věku 12–18 let byl sledován morfologický typ nohy, index nohy pro hodnocení podélné klenby nožní, vyosení palce a malíku, úhel paty a stav svalstva dolních končetin. U chlapců i dívek byla nalezena výrazně vyšší frekvence výskytu nohy egyptské (71,69 % a 70,99 %. Noha kvadratická se vyskytovala u chlapců ve velmi nízkém procentu (2,83 % s určitou individuální asymetrií, u dívek nalezena nebyla. Diagnostika plochonoží metodou Chippauxe–Šmiřáka poskytla velmi příznivé výsledky (4,94–10,38 % výskytu ploché nohy, metoda podle Szritera–Godunova naopak nález podstatně horší (38,2–43,21 % výskytu ploché nohy. S nulovým stavem vyosení palce jsme se setkali u necelé čtvrtiny souborů. U souboru chlapců byla četnost projevu valgozity a varozity palce téměř vyrovnána, věcně převažovalo varózní postavení palce vpravo. U souboru dívek dominovalo signifikantně valgózní postavení. Průměrné hodnoty se pohybovaly v rozmezí 4 až 7 stupňů. Průměrná hodnota úhlu malíku, charakterizující vbočený malík, byla vysoká (17,73 až 21,90 stupně. Průměrný úhel paty byl diagnostikován v rozmezí 15 až 18 stupňů. Při hodnocení vztahů mezi zkrácením svalů dolní končetiny a poruchami funkčního stavu klenby nožní (pouze u mužů jsme nalezli potvrzení statistické významnosti závislosti u vyosení paty a zkrácení m. triceps surae sin. a signifikantní závislost mezi úhlem paty a zkrácením flexorů kolen sin. Morphological foot type, foot index for longitudinal foot vault, misalignment of the big and little toes, heel angle and lower limb muscles condition were monitored in 106 male students and 162 female students from the Gymnasium school in Šternberk and the Integrated secondary school in Ostrava ranging in age from 12 to 18 years. A considerably

Development and Experimental Study of Phantoms for Mapping Skin Chromophores

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Silapetere A.

2014-06-01

Full Text Available Mūsdienās multispektrālās attēlošanas iekārtas izmanto ādas parametru un fizioloģisko procesu aprakstīšanai gan pētniecības, gan diagnostikas nolūkiem. Iekārtu darbības uzlabošanai ir nepieciešams labāk saprast gaismas mijiedarbību ar audiem, kā arī veikt šo iekārtu kalibrēšanu ar ādas maketu. Redzamā un tuvā infrasarkanā optiskā diapazona spektroskopijā ir svarīgi ādas maketi, kas simulē audu slāņaino struktūru un ķīmiskās īpašības, kā arī maketi, kas ir bioloģiski līdzvērtīgi. Šajā pētījumā tika izveidots ādas makets no bioloģiskām un ķīmiski sintezētām struktūrām. Ādas maketa izveidei tika izmantota fibrīna matrica ar dermālo un epidermālo šūnu piejaukumu, lai imitētu ādas slāņaino struktūru. Fibrīna matrica tiek veidota no 0,47 ml asins plazmas, 0,4 ml fizioloģiskā šķīduma, 0,8 μl treneksāmskābes un 89,4 μl kalcija glukanāta. Izveidoto matricu ievieto šūnu inkubatorā, lai tā polimerizētos. Nākošais slānis tiek veidots ar dermālo šūnu piejaukumu (180-270 šūnas, un pēdējais fibrīna matriksa slānis tiek veidots ar epidermālo šūnu piejaukumu (270 šūnas un šūnu augšanu veicinošu serumu (FBS. Šūnu kultivēšanai nepieciešamas vismaz divas nedēļas. Šajā slāņainajā struktūrā ir iespējams pievienot ādas hromoforu simulējošus iekļāvumus. Optiskajā diapazonā no 450-900 nm ādas hromoforas, kurām ir visizteiktākais spektrs, ir bilirubīns, melanīns un hemoglobīns. Lai simulētu ādas hromoforu spektrālās īpašības, tika izmantots sintezēts bilirubīns, eritrocītu masa un nigrozīns. Lai izpētītu šī maketa iekārtu kalibrēšanas potenciālu, tika izveidoti 76 paraugi, kur katros 24 paraugos bija pievienots viens no absorbentiem ar dažādām koncentrācijām. Pilna ādas maketa audzēšanai nepieciešamas divas nedēļas, lai ātrāk tiktu iegūti pirmie rezultāti tika veidoti maketi bez dermālo un epiderm

Metabolism of fission products in man: Marshallese experience; Metabolisme des produits de fission radioactifs chez l'homme: donnees recueillies aux iles Marshall; Metabolizm radioaktivnykh produktov deleniya v organizme cheloveka. (dannye obsledovaniya zhite- lej marshal'skikh ostrovov); Metabolismo de productos de fision radiactivos en el hombre: datos obtenidos en los habitantes de las islas Marshall

Energy Technology Data Exchange (ETDEWEB)

Cohn, S. H. [Brookhaven National Laboratory, Upton, Long Island, NY (United States)

1963-02-15

gracias a estos estudios. Presenta los resultados de un tratamiento con la sal calcico-disodica del EDTA, que se efectuo poco despues de la contaminacion con el proposito de modificar la velocidad de eliminacion de las mezclas de productos de fision en los habitantes de las islas Marshall. Tambien discute el metabolismo de los radionuclidos y su relacion con la radiactividad ambiente en aquella zona. (author) [Russian] Meditsinskoe'obsledovanie zhitelej Marshal'skikh ostrovov, sluchajno podvergshikhsya dejstviyu mestnykh radioaktivnykh osadkov v 1954 godu, yavlyaetsya unikal'nym v tom smysle, chto ono, naryadu s obsledovaniem yaponskikh rybakov, daet vozmozhnost' poluchit' edinstvennye v ehtoj oblasti dannye po metabolizmu smeshannykh produktov deleniya v organizmakh lyudej. Rannyaya diagnostika vnutrennego radioaktivnogo zarazheniya osushchestvlyalas' s pomoshch'yu radiokhimicheskogo analiza vydelenij obluchennykh lyudej i metodami radiokhimicheskogo analiza tkanej zhivotnykh obluchennykh odno-vremenno. Na nachal'noj stadii bol'shuyu chast' vnutrennej dozy radiatsii sostavlyali strontsij-89, barij-140, jod-131, ikh bolee korotkozhivushchie dochernie produkty i ryad redkozemel'nykh ehlementov. Cherez god osnovnymi radioizotopami byli strontsij-90, tsezij-137 i tsink-65. Pozdnee periodi- cheski izmeryalas' aktivnost' ehtikh radioizotopov, a eshche pozdnee i kobal'ta-60. Nachinaya s 1958 goda gamma-spektry u zhitelej Marshal'skikh ostrovov poluchayut s pomoshch'yu portativnogo schetchika dlya izmereniya aktivnosti vsego tela. V doklade obsuzhdayutsya dannye ehtikh issledovanij za prshedshie vosem' let. Privodyatsya rezul'taty rannikh popytok izmenit' skorost' udaleniya smeshannykh produktov deleniya iz organizma s pomoshch'yu dvunatrievogo kal'tsiya EDTA. Obsuzhdaetsya takzhe metabolizm radioizotopov i svyaz'ikh s urovnyami v okruzhayushchej srede. (author)

Results of Positron Scanning in 1200 Cases for Diagnosis of Intracranial Lesions; Diagnostic de 1200 Cas de Lesions Intracraniennes par Scintigraphy au Moyen de Positons; Rezul'taty 1200 sluchaev pozitronnogo skennirovaniya llya ustanovleniya diagnoza vnutricherepnykh zabolevanij; Exploracion Positronica para el Diagnostico de Lesiones Intracraneanas: Resultados de 1200 Casos

Energy Technology Data Exchange (ETDEWEB)

Wilcke, O. [Neurochirurgische Universitaetsklinik, Cologne, Federal Republic of Germany (Germany)

1964-10-15

. Jeto osobenno spravedlivo v otnoshenii medi-64 (period poluraspada 12,8 chasov), kotoraja mozhet primenjat'sja dlja issledovanija ambulatornyh bol'nyh. Vid opuholi mozhet byt' opredelen po koncentracii v nej radioaktivnogo veshhestva. Eshhe luchshe razrabotana diagnostika tipa opuholi v kombinacii s antogra- fiej sosudov golovnogo mozga, chto ochen' vazhno pri opredelenii pokazanij k operacii. V dannom issledovanii tochnost' diagnoza sostavljala 75 -80% vseh sluchaev opuholej golovnogo mozga. K zabolevanijam, kotorye legche vsego raspoznajutsja vsledstvie ih vysokoj sposobnosti koncentrirovat' ukazannye izotopy, otnosjatsja meningiomy, abscessy i glioblastomy, togda kak oligodendrogliomy i astrocitomy v men'shej stepeni sposobny koncentrirovat' radioaktivnye veshhestva i pojetomu raspoznajutsja trudnee. Gruppa astrocitom i pochti vse jepidermoidnye opuholi ne sposobny koncentrirovat' radioaktivnye veshhestva i v jetih sluchajah kombinacija s antografiej sosudov golovnogo mozga imeet vazhnoe znachenie dlja ustanovlenija diagnoza. Metod pozitronnogo skennirovanija okazalsja ochen' cennym pri iskljuchenii diagnoza opuholi v sluchajah predpolagaemoj simptomaticheskoj jepilepsii; tochnost' diagnoza sostavljaet zdes'jao 90%. Pri kombinacii jelektrojencefalografii so skenniro- vaniem obnaruzhena odinakovaja tochnost' kak pri ustanovlenii, tak i pri iskljuchenii diagnoza opuholi, chto pozvolit obojtis' bez arteriografii i/ili gospitalizacii vo vseh sluchajah, kogda poluchena kombinacija otricatel'nyh dannyh i otsutstvujut simptomy bolezni. Jeto podtverzhdaet cennost' metoda pri obsledovanii ambulatornyh bol'nyh. (author)