Wilson, Sigismond Ayodele
Using an actor-oriented approach to political ecology integrated with theory on the social production of scale, this dissertation examines the extent to which diamond exploitation constitutes a resource curse in Sierra Leone, with Kono District as a case-study. It uses social survey methods and remote sensing analysis of Landsat images to (1) evaluate the role of Sierra Leone's diamonds in economic development from a historical lens, (2) examine the extent to which a weak regulatory state apparatus makes a rich diamond endowment more of a curse than a blessing, (3) determine whether geographically diffuse and remotely-located diamonds are more a liability than an asset, and (4) assess whether environmental conditions are worse in diamond than in non-diamond chiefdoms. Results of the study showed that the contribution of diamonds to national economic growth declined precipitously following the politicization of diamonds and growing informalization of mining under the leadership of Siaka Stevens. Growing disenchantment combined with grievances over access to diamond resources and rights, culminating in a civil war fuelled by conflict diamonds. Findings indicated that actors capitalized on a weak regulatory state to fulfill their agendas. Illicit diamond exploitation was mainly driven by corruption, economic constraints and perverse economic incentives. Preferential land allocation to industrial mining following World Bank Group-directed national mining policy reforms and the weakness of the state in ensuring companies' adherence to mining clauses precipitated corporation-community conflicts. Study findings showed that the resource curse was acute on diggers who received less than 1 a day unlike their South American counterparts who made at least 7 daily. Results from the study demonstrate that the spatiality of diamonds also contributed to the resource curse. Illicit diamond mining was more acute in remotely located mining sites than in extractive sites closer to
Full Text Available Abstract Background During December 2014–February 2015, an Ebola outbreak in a village in Kono district, Sierra Leone, began following unsafe funeral practices after the death of a person later confirmed to be infected with Ebola virus. In response, disease surveillance officers and community health workers, in collaboration with local leadership and international partners, conducted 1 day of active surveillance and health education for all households in the village followed by ongoing outreach. This study investigated the impact of these interventions on the outbreak. Methods Fifty confirmed Ebola cases were identified in the village between December 1, 2014 and February 28, 2015. Data from case investigations, treatment facility and laboratory records were analyzed to characterize the outbreak. The reproduction number (R was estimated by fitting to the observed distribution of secondary cases. The impact of the active surveillance and health education was evaluated by comparing two outcomes before and after the day of the interventions: 1 the number of days from symptom onset to case-patient isolation or death and 2 a reported epidemiologic link to a prior Ebola case. Results The case fatality ratio among the 50 confirmed Ebola cases was 64.0 %. Twenty-three cases occurred among females (46.0 %; the mean age was 39 years (median: 37 years; range: 5 months to 75 years. Forty-three (87.8 % cases were linked to the index case; 30 (61.2 % were either at the funeral of Patient 1 or had contact with him while he was ill. R was 0.93 (95 % CI: 0.15–2.3; excluding the funeral, R was 0.29 (95 % CI: 0.11–0.53. The mean number of days in the community after onset of Ebola symptoms decreased from 4.0 days (median: 3 days; 95 % CI: 3.2–4.7 before the interventions to 2.9 days (median: 2 days; 95 % CI: 1.6–4.3 afterward. An epidemiologic link was reported in 47.6 % of case investigations prior to and 100 % after the interventions
Subrahmanyam, C.; Gireesh, R.; Chand, S.; KameshRaju, K.A.; Rao, D.G.
] N. Furus, Y. Kono, Slab residual gravity anomaly: gravity reduction due to subducting plates beneath the Japanese Islands, J. Geodyn. 36 (2003) 497-514. 19  S Dasgupta, M. Mukhopadhyay, A. Bhattacharya, T. K. Jana, The geometry...
Full Text Available Josef Finsterer,1 Sinda Zarrouk-Mahjoub21Krankenanstalt Rudolfstiftung, Vienna, Austria; 2Genomics Platform, Pasteur Institute of Tunis, Tunis, Tunisia We read with great interest the article, by Kono et al, about a 32-year-old male with Duchenne muscular dystrophy (DMD, who was admitted for dilated cardiomyopathy manifesting as heart failure, left bundle branch block, Mobitz-II block, bradycardia, and arterial hypotension. He profited from implantation of a cardiac resynchronization therapy-D system with a defibrillator and beta-blocker treatment. View original article by Kono et al.
Visser, Benjamin Jelle
Podoconiosis or "endemic non-filarial elephantiasis" is a tropical disease caused by prolonged exposure of bare feet to irritant alkaline clay soils of volcanic origin . The name of the disease is derived from the Greek words for foot: podos, and dust: konos. Small mineral particles from irritant
The 2008 Nobel Prize for Physics goes to three physicists who have worked on broken symmetries in particle physics. The announcement of the 2008 Nobel Prize for physics was transmitted to the Globe of Science and Innovation via webcast on the occasion of the preview of the Nobel Accelerator exhibition.On 7 October it was announced that the Royal Swedish Academy of Sciences had awarded the 2008 Nobel Prize for physics to three particle physicists for their fundamental work on the mechanisms of broken symmetries. Half the prize was awarded to Yoichiro Nambu of Fermilab for "the discovery of the mechanism of spontaneous broken symmetry in subatomic physics". The other half is shared by Makato Kobayashi of Japan’s KEK Institute and Toshihide Maskawa of the Yukawa Institute at the University of Kyoto "for the discovery of the origin of the broken symmetry which predicts the existence of at least three families of quarks in Nature". At th...
Van Zeebroeck, M.; Tijskens, E.; Van Liedekerke, P.; Deli, V.; De Baerdemaeker, J.; Ramon, H.
A pendulum device has been developed to measure contact force, displacement and displacement rate of an impactor during its impact on the sample. Displacement, classically measured by double integration of an accelerometer, was determined in an alternative way using a more accurate incremental optical encoder. The parameters of the Kuwabara-Kono contact force model for impact of spheres have been estimated using an optimization method, taking the experimentally measured displacement, displacement rate and contact force into account. The accuracy of the method was verified using a rubber ball. Contact force parameters for the Kuwabara-Kono model have been estimated with success for three biological materials, i.e., apples, tomatoes and potatoes. The variability in the parameter estimations for the biological materials was quite high and can be explained by geometric differences (radius of curvature) and by biological variation of mechanical tissue properties.
Morales, Juan; Goguitchaichvili, Avto; Alva-Valdivia, Luis M.; Urrutia-Fucugauchi, Jaime
Twenty years after Tanaka and Kono's pioneering contribution (Tanaka and Kono, 1984), we give some new details on the effect of applied field strength during Thellier paleointensity experiments. Special attention is paid to the relation of magnitude of laboratory field and Coe's quality factors (Coe et al., 1978). Full thermoremanent magnetizations were imparted on natural samples containing low-Ti titanomagnetites of pseudo-single domain structure in a 40-μT magnetic field from 600 °C to room temperature. The samples were subjected to the routine Thellier procedure using a wide range of applied laboratory fields. Results indicate that values of laboratory fields may be accurately reproduced within 2% of standard error. The quality factors, however, decrease when the magnitude of 'ancient' field does not match to applied laboratory fields. To cite this article: J. Morales et al., C. R. Geoscience 338 (2006).
range from 43-49 km. Kono  examined the Bouguer gravity in eastern Nepal and found that the crust under the Himalayas is much thinner than...December 13, 1982 Yemen earthquake is of considerable interest because it is historically the first earthquake in the southwestern Arabian Peninsula...southwest boundary of the Arabian Peninsula, which is relatively seismically inactive, has been characterized by Ambraseys and Meiville (1983) as couple
8603171, 1586. Muroki, Kono, Nagao, A., " Mazda Rotary Engine Technology Combustion Characteristics," Mazda Motor Corporation, IECEC 869086, 1986...Muroki, T., Miyata J., "Material Technology Development Applied to Rotary Engine at Mazda ," SAE 8605601, 1986. 84 Laa .fn tr) l a l ~ l lf n S l l ff...system for starting and control power as described in the PD. The cranking system consists of a cranking motor ; start solenoid; batteries; battery
Mokhtar, T. A., R. B. Herrmann, and D. R. Russell (1988). Seismic velocity and Q model for the shallow structure of the Arabian shield from short...edge of the Tibetan plateau and have thicknesses that range from 43-49 km. Kono (1974) examined the Bouguer gravity in eastern Nepal and found that the...8217.-.- -- - .~~ ~ ~ .. ..... . 37 7 30L iD7. 115 37 30 0 500G 10000 15000 20000 16 7 METERS PRWVf )F MCPLj.NV BOUGUER ORRVITY 12000 KG/1i,31 Figure 1. The Bouguer
Bjørkhaug, I; Hatløy, A
This article describes the implementation of respondent driven sampling (RDS) in a study conducted in Kono District, Sierra Leone. RDS was used to identify children, under the age of 18 years old, working in the diamond sector of Sierra Leone. This includes children working directly as diamond miners as well as children working in the informal sector connected to the diamond field. The article seeks to postulate that RDS is a suitable method for a rapid approach to a population that is unidentified in size and demonstrate how RDS can reach a study population within a limited period.
Lee, S D; Kim, J H
In Korea, the Organ Transplantation Act came into effect in 2000, establishing the Korean Network for Organ Sharing (KONOS) with centralized authority for organ procurement as well as for approval of donors and recipients to ensure fair organ allocation. However, the number of brain-dead donors decreased sharply, and the organ allocation system proved inefficient. The government revised the Organ Transplantation Act in August 2002, introducing an incentive system. If a transplantation hospital formed a Committee for Brain Death Evaluation and a Hospital Organ Procurement Organization, it could receive a kidney from a brain dead-donor as an incentive to foster organ procurement regardless of the KONOS wait list. The government also launched a pilot brain-dead donor registry program to strengthen Hospital Organ Procurement Organization activity. If local hospitals collaborated with specialized hospitals in organ procurement, local hospitals obtained financial incentives. But because the organ shortage problem has not been resolved, the government has proposed four initiatives: first, broadening the incentive system, which makes it possible to give each specialized hospital a choice of one of eight organs from each donor as an incentive; second, development of an Independent Organ Procurement Organization; third introduction of an opt-out system; and last, improvement of the Committee for Brain Death Evaluation system. It is uncertain which initiatives will be adopted, but changes in organ procurement systems are nonetheless considered a key to solve the organ shortage problem in Korea.
Full Text Available Takanori Mizoguchi,1 Shiro Nishigaki,2 Tomoki Sato,3 Harumi Wakiyama,4 Nobuchika Ogino2 1Mizoguchi Eye Clinic, Ophthalmology, Sasebo, 2Nishigaki Eye Clinic, Ophthalmology, Nagoya, 3Sato Eye Clinic, Ophthalmology, Arao, 4Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Japan Background: The purpose of this study was to determine outcomes when using Trabectome surgery and to evaluate factors associated with its effects in primary open-angle glaucoma (POAG and exfoliation glaucoma (EXG. Methods: This was a prospective, non-randomized, observational, comparative cohort study in which Trabectome surgery was used alone in patients with POAG or EXG. Trabectome surgery was considered to have failed when at least one of the following three criteria was fulfilled: intraocular pressure (IOP ≥21 mmHg and a <20% reduction below the baseline IOP on two consecutive follow-up visits 3 months or more after surgery; need for additional glaucoma surgery; and an increase in number of medications compared with baseline. Results: The subjects were 32 males (34 eyes and 46 females (48 eyes. POAG was observed in 43 eyes and EXG in 39 eyes. IOP after Trabectome surgery decreased significantly from 22.3±6.8 mmHg at baseline to 14.0±3.9 mmHg (23.0% reduction at month 24 in all cases (P<0.0000. The success rate at 2 years was 51.2% for all cases (POAG, 50.9%; EXG, 49.2%. There was no significant difference in success rate between POAG and EXG (P=0.91. Preoperative IOP (P=0.033 and number of medications (P=0.041 were significant factors for surgical success/failure in multivariate logistic regression. No serious complications were observed. Conclusion: Trabectome surgery achieved favorable IOP control and was equally effective in patients with POAG and those with EXG. Its effects were influenced by preoperative IOP and number of preoperative medications. Keywords: Trabectome, primary open-angle glaucoma, exfoliation glaucoma, success rate, risk factors
Koroma Joseph B
Full Text Available Abstract Background National mapping of lymphatic filariasis (LF was conducted using Immunochromatographic tests (ICT in 2005 to determine endemicity and geographic spread of the disease. A baseline microfilaria survey was then conducted to determine LF prevalence and microfilaria intensity. Methods In 2005 1,982 persons of 15 years and over from 14 health districts were selected and fingertip blood samples were tested with ICT cards. In 2007-8 blood samples were taken between 10 p.m. and 2 a.m. and examined for microfilaria (mf from 9,288 persons from 16 sentinel sites representing each district and 2 additional sites for districts with populations over 500,000 (Bo and Kenema. Results The overall LF prevalence by ICT cards was 21% (males 28%, females 15%. All districts had a prevalence of Wuchereria bancrofti antigen > 1%. Distribution of LF prevalence showed a strong spatial correlation pattern with high prevalence in a large area in the northeast gradually decreasing to a relatively low prevalence in the southwest coast. High prevalence was found in the northeast, Bombali (52%, Koinadugu (46%, Tonkolili (37% and Kono (30%. Low prevalence was found in the southwest, Bonthe (3% and Pujehun (4%. The mf prevalence was higher in the northeast: Bombali, 6.7%, Koinadugu 5.7%, Port Loko 4.4% and Kono 2.4%. Overall there was a significant difference in mf prevalence by gender: males 2.9%, females 1.8% (p = 0.0002 and within districts in Kailahun, Kono, Port Loko, Moyamba and Koinadugu (all p 20 years (2.5% than in people ≤ 20 years (1.7% (p = 0.043. The overall arithmetic mean mf density was 50.30 mf/ml among mf-positive individuals and 1.19 mf/ml in the population examined which varied significantly between districts. Conclusions The ICT results showed that LF was endemic nationwide and that preventive chemotherapy (PCT was justified across the country. Both the ICT and microfilaraemia surveys found that prevalence was greater in males than females
Audiffren, M.; Traimond, P.; Bardon, J.; Drechsler, M.
Nishigaki and Nakamura have observed zigzag chains on the central (011) face of tungsten after field evaporation at T > 140 K. In this paper, a study of the formation, disappearance and structure of such chains is described. Tungsten tips of small radii down to 60 A were used. Chains of 3 to 9 spots, that are clearly visible, are found even at 90 K. Four different structure models of the zigzag chains are discussed, including the multibranch model proposed by the japanese authors. The interpretation of the experimental results shows fairly clearly that the real zigzag chain structure is a special non-dense structure. It must be formed by a local displacement of the tungsten adatoms in the field. Without the field, a zigzag chain is transformed into a two-dimensional cluster of the nearest neighbour atom by a small increase in temperature. If the field is reintroduced, the cluster can revert to the initial zigzag structure. The zigzag structure is interpreted as being caused by forces of repulsion between the atom dipoles. (Auth.)
Skoric, Milos M.
This material has been prepared and partly delivered in a series of lectures given at NIFS to Doctor course students of the SOKENDAI (Graduate University of Advanced Studies, Japan) in academic 2007/08 year. Special gratitude is due to colleagues for fruitful collaboration: Profs. K. Mima, Lj. Hadzievski, S. Ishiguro, A. Maluckov, M. Rajkovic and Dr Li Baiwen and Dr Lj. Nikolic, in particular, and to Prof. Mitsuo Kono for motivating the work on this text. I wish to pay unique tribute to close friends and longtime collaborators, Prof. Dik ter Haar and Prof. Moma Jovanovic who are no longer with us. This report contains Chapter 1 (Strong Langmur Turbulence), Chapter 2 (Wave Collapse in Plasmas), Chapter 3 (Spatiotemporal Complexity in Plasmas), Chapter 4 (Relativistic Plasma Interactions) and Chapter 5 (Ponderomotive Potential and Magnetization). (J.P.N.)
Benjamin Jelle Visser
Full Text Available Podoconiosis or “endemic non-filarial elephantiasis” is a tropical disease caused by prolonged exposure of bare feet to irritant alkaline clay soils of volcanic origin . The name of the disease is derived from the Greek words for foot: podos, and dust: konos. Small mineral particles from irritant soils penetrate the skin and provoke an inflammatory response leading to fibrosis and blockage of lymphatic vessels, causing lymphoedema . Patients suffer from disabling physical effects, but also stigma . The disease can simply be prevented by avoiding contact with irritant soils (wearing shoes but this is still an unaffordable “luxury” for many people. Podoconiosis is unique because it is a completely preventable non-communicable tropical disease . In the past few years, podoconiosis has received increased advocacy and is now step by step appearing on the agenda of medical researchers as well as politicians. [...
Full Text Available Abstract Background The literature on health care seeking behaviour in sub-Saharan Africa for children suffering from malaria is quite extensive. This literature, however, is predominately quantitative and, inevitably, fails to explore how the local concepts of illness may affect people's choices. Understanding local concepts of illness and their influence on health care-seeking behaviour can complement existing knowledge and lead to the development of more effective malaria control interventions. Methods In a rural area of Burkina Faso, four local concepts of illness resembling the biomedical picture of malaria were described according to symptoms, aetiology, and treatment. Data were collected through eight focus group discussions, 17 semi-structured interviews with key informants, and through the analysis of 100 verbal autopsy questionnaires of children under-five diagnosed with malaria. Results Sumaya, dusukun yelema, kono, and djoliban were identified as the four main local illness concepts resembling respectively uncomplicated malaria, respiratory distress syndrome, cerebral malaria, and severe anaemia. The local disease categorization was found to affect both treatment and provider choice. While sumaya is usually treated by a mix of traditional and modern methods, dusukun yelema and kono are preferably treated by traditional healers, and djoliban is preferably treated in modern health facilities. Besides the conceptualization of illness, poverty was found to be another important influencing factor of health care-seeking behaviour. Conclusion The findings complement previous evidence on health care-seeking behaviour, by showing how local concepts of illness strongly influence treatment and choice of provider. Local concepts of illness need to be considered when developing specific malaria control programmes.
Full Text Available Kazuyuki Kumagai,1 Mariko Furukawa,1 Tetsuyuki Suetsugu,1 Nobuchika Ogino2 1Department of Ophthalmology, Kami-iida Daiichi General Hospital, 2Department of Ophthalmology, Nishigaki Eye Clinic, Aichi, Japan Purpose: To report the findings in three cases in which the average foveal thickness was increased after a thin epiretinal membrane (ERM was removed by vitrectomy with internal limiting membrane (ILM peeling.Methods: The foveal contour was normal preoperatively in all eyes. All cases underwent successful phacovitrectomy with ILM peeling for a thin ERM. The optical coherence tomography (OCT images were examined before and after the surgery. The changes in the average foveal (1 mm thickness and the foveal areas within 500 µm from the foveal center were measured. The postoperative changes in the inner and outer retinal areas determined from the cross-sectional OCT images were analyzed.Results: The average foveal thickness and the inner and outer foveal areas increased significantly after the surgery in each of the three cases. The percentage increase in the average foveal thickness relative to the baseline thickness was 26% in Case 1, 29% in Case 2, and 31% in Case 3. The percentage increase in the foveal inner retinal area was 71% in Case 1, 113% in Case 2, and 110% in Case 3, and the percentage increase in foveal outer retinal area was 8% in Case 1, 13% in Case 2, and 18% in Case 3.Conclusion: The increase in the average foveal thickness and the inner and outer foveal areas suggests that a centripetal movement of the inner and outer retinal layers toward the foveal center probably occurred due to the ILM peeling. Keywords: internal limiting membrane, optical coherence tomography, average foveal thickness, epiretinal membrane, vitrectomy
Koroma, Joseph B.; Peterson, Jen; Gbakima, Aiah A.; Nylander, Francis E.; Sahr, Foday; Soares Magalhães, Ricardo J.; Zhang, Yaobi; Hodges, Mary H.
Background A national baseline mapping of schistosomiasis and soil-transmitted helminthiasis (STH) was performed in Sierra Leone. The aim was to provide necessary tools for the Ministry of Health and Sanitation to plan the intervention strategies in the national integrated control program on neglected tropical diseases according to the World Health Organization (WHO) guidelines for preventative chemotherapy (PCT) and for future monitoring and evaluation. Methodology/Principal Findings 53 primary schools were randomly selected through a two-staged random sampling throughout the country. Approximately one hundred children aged 5–16 years of age were systematically selected from each school and their stool samples examined in a field laboratory. A total of 5,651 samples were examined. Data were analyzed with multivariable logistic regression models using model-based geostatistics. Spatial analysis predicted that S. mansoni infection was positively associated with population density and elevation and that there was a large cluster of high risk of S. mansoni infection (prevalence >70%) in the north and most of the eastern areas of the country, in line with the observed prevalence in Kono (63.8–78.3%), Koinadugu (21.6–82.1%), Kailahun (43.5–52.6%), Kenema (6.1–68.9%) and Tonkolili (0–57.3%). Hookworm infection was negatively associated with population density and land surface temperature, and was high across Sierra Leone with a large cluster of high infection risk (prevalence >70%) in the north-eastern part of the country. Remarkably low prevalence of Ascaris lumbricoides (7.2%) and Trichuris trichiura (3.3%) was recorded when compared with results published in the 1990s. Conclusions/Significance Results justify PCT for schistosomiasis for school age children and at-risk adults every year in high-risk communities in five districts and every two years in moderate-risk communities in one more district. The high prevalence of STH, particularly hookworm, coupled
Background Schistosomiasis and soil-transmitted helminthiasis (STH) are endemic in Sierra Leone confirmed by national mapping in 2008. To better inform planning of preventive chemotherapy strategy, another survey was conducted before mass drug administration (MDA) in seven districts according to the mapping results or local knowledge. Fifty-nine chiefdoms and one school in every chiefdom were selected. Thirty school children aged 9-14 years from each school (total: 1760) were examined by parasitological methods for infection with Schistosoma mansoni and STHs. Results The overall prevalence of S. mansoni was 40.2% (95% confidence interval (CI): 37.9-42.5%), particularly in Kailahun (63.3%), Kenema (46.7%), Koinadugu (41.9%) and Kono (71.7%). The results demonstrated the focal distribution of S. mansoni in Bo, Tonkolili and Bombali districts with prevalence ranging from 0.0-63.3%, 3.3-90.0% and 0.0-67.9% respectively. The arithmetic mean intensity of S. mansoni infection was 95.4 epg (95% CI: 61.4-129.5 epg), Heavy mean intensity of infection was found in Kailahun (120.2 epg), Kenema (104.5 epg), Koinadugu (112.3 epg) and Kono (250.3 epg). Heavy or moderate infection with S. mansoni occurred in 20.7% of children examined. Hookworm prevalence was moderate: 31.2% (95% CI: 29.1-33.4%), but high in Bo (50.0%) and Tonkolili (56.7%). Hookworm intensity of infection was light with a mean epg of 53.0 (95% CI: 38.4-67.7 epg). Prevalence and intensity of Ascaris lumbricoides (1.5%, 17.8 epg) and Trichuris trichiura (2.5%, 20.3 epg) was low. Conclusions The prediction by previous spatial analysis that S. mansoni was highly endemic across north-eastern Sierra Leone was confirmed with a significant proportion of children heavily or moderately infected. The distribution of S. mansoni in Bo, Tonkolili and Bombali districts ranged widely, highlighting the importance of considering the nature of focal transmission in national mapping exercises. These results were used to refine the
Hodges, Mary; Dada, Nsa; Wamsley, Anna; Paye, Jusufu; Nyorkor, Emanuel; Sonnie, Mustapha; Barnish, Guy; Bockarie, Moses; Zhang, Yaobi
Schistosomiasis and soil-transmitted helminthiasis (STH) are endemic in Sierra Leone confirmed by national mapping in 2008. To better inform planning of preventive chemotherapy strategy, another survey was conducted before mass drug administration (MDA) in seven districts according to the mapping results or local knowledge. Fifty-nine chiefdoms and one school in every chiefdom were selected. Thirty school children aged 9-14 years from each school (total: 1760) were examined by parasitological methods for infection with Schistosoma mansoni and STHs. The overall prevalence of S. mansoni was 40.2% (95% confidence interval (CI): 37.9-42.5%), particularly in Kailahun (63.3%), Kenema (46.7%), Koinadugu (41.9%) and Kono (71.7%). The results demonstrated the focal distribution of S. mansoni in Bo, Tonkolili and Bombali districts with prevalence ranging from 0.0-63.3%, 3.3-90.0% and 0.0-67.9% respectively. The arithmetic mean intensity of S. mansoni infection was 95.4 epg (95% CI: 61.4-129.5 epg), Heavy mean intensity of infection was found in Kailahun (120.2 epg), Kenema (104.5 epg), Koinadugu (112.3 epg) and Kono (250.3 epg). Heavy or moderate infection with S. mansoni occurred in 20.7% of children examined. Hookworm prevalence was moderate: 31.2% (95% CI: 29.1-33.4%), but high in Bo (50.0%) and Tonkolili (56.7%). Hookworm intensity of infection was light with a mean epg of 53.0 (95% CI: 38.4-67.7 epg). Prevalence and intensity of Ascaris lumbricoides (1.5%, 17.8 epg) and Trichuris trichiura (2.5%, 20.3 epg) was low. The prediction by previous spatial analysis that S. mansoni was highly endemic across north-eastern Sierra Leone was confirmed with a significant proportion of children heavily or moderately infected. The distribution of S. mansoni in Bo, Tonkolili and Bombali districts ranged widely, highlighting the importance of considering the nature of focal transmission in national mapping exercises. These results were used to refine the MDA for schistosomiasis control
Koroma, Joseph B; Peterson, Jen; Gbakima, Aiah A; Nylander, Francis E; Sahr, Foday; Soares Magalhães, Ricardo J; Zhang, Yaobi; Hodges, Mary H
A national baseline mapping of schistosomiasis and soil-transmitted helminthiasis (STH) was performed in Sierra Leone. The aim was to provide necessary tools for the Ministry of Health and Sanitation to plan the intervention strategies in the national integrated control program on neglected tropical diseases according to the World Health Organization (WHO) guidelines for preventative chemotherapy (PCT) and for future monitoring and evaluation. 53 primary schools were randomly selected through a two-staged random sampling throughout the country. Approximately one hundred children aged 5-16 years of age were systematically selected from each school and their stool samples examined in a field laboratory. A total of 5,651 samples were examined. Data were analyzed with multivariable logistic regression models using model-based geostatistics. Spatial analysis predicted that S. mansoni infection was positively associated with population density and elevation and that there was a large cluster of high risk of S. mansoni infection (prevalence >70%) in the north and most of the eastern areas of the country, in line with the observed prevalence in Kono (63.8-78.3%), Koinadugu (21.6-82.1%), Kailahun (43.5-52.6%), Kenema (6.1-68.9%) and Tonkolili (0-57.3%). Hookworm infection was negatively associated with population density and land surface temperature, and was high across Sierra Leone with a large cluster of high infection risk (prevalence >70%) in the north-eastern part of the country. Remarkably low prevalence of Ascaris lumbricoides (7.2%) and Trichuris trichiura (3.3%) was recorded when compared with results published in the 1990s. Results justify PCT for schistosomiasis for school age children and at-risk adults every year in high-risk communities in five districts and every two years in moderate-risk communities in one more district. The high prevalence of STH, particularly hookworm, coupled with widespread anemia according to a national report in Sierra Leone, suggests
Pieterse, Pieternella; Lodge, Tom
Sierra Leone is one of three countries recently affected by Ebola. In debates surrounding the circumstances that contributed to the initial failure to contain the outbreak, the word 'trust' is often used: In December 2014, WHO director Margret Chan used 'lack of trust in governments'; The Lancet's Editor-in-Chief, wrote how Ebola has exposed the '… breakdown of trust between communities and their governments.' This article explores the lack of trust in public healthcare providers in Sierra Leone, predating the Ebola outbreak, apparently linked to widespread petty corruption in primary healthcare facilities. It compares four NGO-supported accountability interventions targeting Sierra Leone's primary health sector. Field research was conducted in Kailahun, Kono and Tonkolili Districts, based on interviews with health workers and focus group discussions with primary healthcare users. Field research showed that in most clinics, women and children entitled to free care routinely paid for health services. A lack of accountability in Sierra Leone's health sector appears pervasive at all levels. Petty corruption is rife. Understaffing leads to charging for free care in order to pay clinic-based 'volunteers' who function as vaccinators, health workers and birth attendants. Accountability interventions were found to have little impact on healthworker (mis)behaviour. © The Author 2015. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: email@example.com.
Liu, Jia-Hang; Shan, Xin-Jian; Yin, Jing-Yuan
In the high-resolution images, the undamaged buildings generally show a natural textural feature, while the damaged or semi-damaged buildings always exhibit some low-grayscale blocks because of their coarsely damaged sections. If we use a proper threshold to classify the grayscale of image, some independent holes will appear in the damaged regions. By using such statistical information as the number of holes in every region, or the ratio between the area of holes and that of the region, etc, the damaged buildings can be separated from the undamaged, thus automatic detection of damaged buildings can be realized. Based on these characteristics, a new method to automatically detect the damage buildings by using regional structure and statistical information of texture is presented in the paper. In order to test its validity, 1-m-resolution iKonos merged image of the 2001 Bhuj earthquake and grayscale aerial photos of the 1976 Tangshan earthquake are selected as two examples to automatically detect the damaged buildings. Satisfied results are obtained.
Low, Van Lun; Adler, Peter H; Sofian-Azirun, Mohd; Srisuka, Wichai; Saeung, Atiporn; Huang, Yao-Te; Hadi, Upik Kesumawati; Da Pham, Xuan; Takaoka, Hiroyuki
Allopatric populations present challenges for biologists working with vectors. We suggest that conspecificity can be concluded in these cases when data from four character sets-chromosomal, ecological, molecular, and morphological-express variation no greater between the allopatric populations than between corresponding sympatric populations. We use this approach to test the conspecificity of Simulium nodosum Puri on the mainland of Southeast Asia and Simulium shirakii Kono & Takahasi in Taiwan. The validity of these two putative species has long been disputed given that they are morphologically indistinguishable. The mitochondria-encoded cytochrome c oxidase subunit I (COI), 12S rRNA, and 16S rRNA genes and the nuclear-encoded 28S rRNA gene support the conspecific status of S. nodosum from Myanmar, Thailand, and Vietnam and S. shirakii from Taiwan; 0 to 0.19 % genetic differences between the two taxa suggest intraspecific polymorphism. The banding patterns of the polytene chromosomes of the insular Taiwanese population of S. shirakii and mainland populations of S. nodosum are congruent. The overlapping ranges of habitat characteristics and hosts of S. nodosum and S. shirakii corroborate the chromosomal, molecular, and morphological data. Four independent sources of evidence (chromosomes, DNA, ecology, and morphology) support the conspecificity of S. nodosum and S. shirakii. We, therefore, synonymize S. shirakii with S. nodosum. This study provides a guide for applying the procedure of testing conspecificity to other sets of allopatric vectors.
Full Text Available This article contains two-dimensional (2D NMR experimental data, obtained by the Bruker BioSpin 500Â MHz NMR spectrometer (Germany which can used for the determination of primary structures of schizophyllan from Schizophyllum commune (SPG and a water-soluble Î²-(1â3, 1â6-glucan from Aureobasidium pullulans. Data include analyzed the 2D NMR spectra of these Î²-glucans, which are related to the subject of an article in Carbohydrate Polymers, entitled âNMR spectroscopic structural characterization of a water-soluble Î²-(1â3, 1â6-glucan from A. pullulansâ (Kono et al., 2017 . Data can help to assign the 1H and 13C chemical shifts of the structurally complex polysaccharides. Keywords: NMR, Î²-(1â3, 1â6-glucan, Aureobasidium pullulans, Schizophyllan, Spectral data
Full Text Available This article is concerned with redefining the notion of information from a perspective of systems theory. In recent years, the notion of information, which was closely related to the framework of old cybernetics, has been refined in parallel with the emergence of new cybernetics, especially second-order cybernetics and autopoiesis. The systemic view of new cybernetics provides us with the notion of “informationally closed system.” This notion is congruent with the epistemological implications of radical constructivism. In order to help understand this argument, we aim at highlighting the development of autopoietic systems theory in Japan. Autopoiesis has often been considered as a thoroughly closed system in Japan, where the relationships between autopoiesis and radical constructivism have frequently been overlooked. This is mainly because the importance which autopoietic systems theory originally attaches to the notion of observer and observation has been inadequately discussed, and autopoietic systems theory is regarded as distinct from second-order cybernetics and radical constructivism. However, they must be dealt with together, and Humberto Maturana should be given credit for his ontology of observing. Since the publication of his paper “Biology of Cognition,” Maturana has been attempting to explain the notion of observation as a biological phenomenon in his own way. Likewise, by taking into consideration the notion of observation, we can build a unified theory of information. Fundamental Informatics, which is being developed by Toru Nishigaki, outlines a unified approach to information by putting human observers at the center of his theory. Social and mechanical information is generated only when human observers conduct observations on the basis of biological information, and this mechanism of generation of information is discussed through the notion of “hierarchical autonomous system.” For an autopoietic organi- zation to be
Journal of Physics: Condensed Matter staff for their help, patience and professionalism. Since this is a fast-moving field, there is absolutely no way of presenting definitive answers to all open questions, but we hope that this special section will provide an overview of the current state of knowledge regarding this topic. Furthermore, we hope that the exciting science and technology described in this section will attract and inspire other researchers and students working in related fields to enter into the study of ultrafast and nonlinear optical phenomena in carbon-based nanostructures. Ultrafast and nonlinear optics in carbon nanomaterials contents Ultrafast and nonlinear optics in carbon nanomaterialsJunichiro Kono The impact of pump fluence on carrier relaxation dynamics in optically excited grapheneT Winzer and E Malic Time-resolved spectroscopy on epitaxial graphene in the infrared spectral range: relaxation dynamics and saturation behaviorS Winnerl, F Göttfert, M Mittendorff, H Schneider, M Helm, T Winzer, E Malic, A Knorr, M Orlita, M Potemski, M Sprinkle, C Berger and W A de Heer Nonlinear optics of graphene in a strong magnetic fieldXianghan Yao and Alexey Belyanin Theory of coherent phonons in carbon nanotubes and graphene nanoribbonsG D Sanders, A R T Nugraha, K Sato, J-H Kim3, J Kono3, R Saito and C J Stanton Non-perturbative effects of laser illumination on the electrical properties of graphene nanoribbons Hernán L Calvo, Pablo M Perez-Piskunow, Horacio M Pastawski, Stephan Roche and Luis E F Foa Torres Transient absorption microscopy studies of energy relaxation in graphene oxide thin film Sean Murphy and Libai Huang Femtosecond dynamics of exciton localization: self-trapping from the small to the large polaron limit F X Morrissey, J G Mance, A D Van Pelt and S L Dexheimer
Mary H Hodges
Full Text Available BACKGROUND: A national mapping of Schistosoma haematobium was conducted in Sierra Leone before the mass drug administration (MDA with praziquantel. Together with the separate mapping of S. mansoni and soil-transmitted helminths, the national control programme was able to plan the MDA strategies according to the World Health Organization guidelines for preventive chemotherapy for these diseases. METHODOLOGY/PRINCIPAL FINDINGS: A total of 52 sites/schools were selected according to prior knowledge of S. haematobium endemicity taking into account a good spatial coverage within each district, and a total of 2293 children aged 9-14 years were examined. Spatial analysis showed that S. haematobium is heterogeneously distributed in the country with significant spatial clustering in the central and eastern regions of the country, most prevalent in Bo (24.6% and 8.79 eggs/10 ml, Koinadugu (20.4% and 3.53 eggs/10 ml and Kono (25.3% and 7.91 eggs/10 ml districts. By combining this map with the previously reported maps on intestinal schistosomiasis using a simple probabilistic model, the combined schistosomiasis prevalence map highlights the presence of high-risk communities in an extensive area in the northeastern half of the country. By further combining the hookworm prevalence map, the at-risk population of school-age children requiring integrated schistosomiasis/soil-transmitted helminth treatment regimens according to the coendemicity was estimated. CONCLUSIONS/SIGNIFICANCE: The first comprehensive national mapping of urogenital schistosomiasis in Sierra Leone was conducted. Using a new method for calculating the combined prevalence of schistosomiasis using estimates from two separate surveys, we provided a robust coendemicity mapping for overall urogenital and intestinal schistosomiasis. We also produced a coendemicity map of schistosomiasis and hookworm. These coendemicity maps can be used to guide the decision making for MDA strategies in combination
The International Atomic Energy Agency (IAEA) and the Government of Japan signed an agreement today aimed at enhancing nuclear security measures for the summer Olympic Games and Paralympic Games in Tokyo in 2020. The agreement follows previous IAEA support to major public events, including the 2016 Olympic Games in Rio de Janeiro and the 2012 European soccer championship in Poland and Ukraine. IAEA Director General Yukiya Amano and Japanese Foreign Minister Taro Kono presided over the signing ceremony at the Agency’s headquarters in Vienna. Practical Arrangements outlining the planned cooperation were signed by IAEA Deputy Director General Juan Carlos Lentijo, head of the Department of Nuclear Safety and Security, and H.E. Mitsuru Kitano, Japan’s Ambassador to the International Organizations in Vienna. “The IAEA has extensive experience in supporting Member States on nuclear security for major public events,” Amano said at the ceremony. “The Agency welcomes the cooperation to support the Olympic and Paralympic Games in Tokyo, and is already cooperating with Japan by sharing the experiences of Member States which previously hosted the Olympics.” The details of the cooperation will be decided in due course, but the possible areas of cooperation include the IAEA offering Japanese authorities training courses, workshops, technical visits and exercises related to nuclear security, hosting preparatory technical meetings and lending supplementary radiation detection equipment. The IAEA and Japan may also exchange information related to nuclear security events as appropriate and through the cooperation, the IAEA will also benefit from Japan’s good practices on nuclear security.
Hodges, Mary H; Soares Magalhães, Ricardo J; Paye, Jusufu; Koroma, Joseph B; Sonnie, Mustapha; Clements, Archie; Zhang, Yaobi
A national mapping of Schistosoma haematobium was conducted in Sierra Leone before the mass drug administration (MDA) with praziquantel. Together with the separate mapping of S. mansoni and soil-transmitted helminths, the national control programme was able to plan the MDA strategies according to the World Health Organization guidelines for preventive chemotherapy for these diseases. A total of 52 sites/schools were selected according to prior knowledge of S. haematobium endemicity taking into account a good spatial coverage within each district, and a total of 2293 children aged 9-14 years were examined. Spatial analysis showed that S. haematobium is heterogeneously distributed in the country with significant spatial clustering in the central and eastern regions of the country, most prevalent in Bo (24.6% and 8.79 eggs/10 ml), Koinadugu (20.4% and 3.53 eggs/10 ml) and Kono (25.3% and 7.91 eggs/10 ml) districts. By combining this map with the previously reported maps on intestinal schistosomiasis using a simple probabilistic model, the combined schistosomiasis prevalence map highlights the presence of high-risk communities in an extensive area in the northeastern half of the country. By further combining the hookworm prevalence map, the at-risk population of school-age children requiring integrated schistosomiasis/soil-transmitted helminth treatment regimens according to the coendemicity was estimated. The first comprehensive national mapping of urogenital schistosomiasis in Sierra Leone was conducted. Using a new method for calculating the combined prevalence of schistosomiasis using estimates from two separate surveys, we provided a robust coendemicity mapping for overall urogenital and intestinal schistosomiasis. We also produced a coendemicity map of schistosomiasis and hookworm. These coendemicity maps can be used to guide the decision making for MDA strategies in combination with the local knowledge and programme needs.
Li Shenjiang; Xiao Xiangsheng; Li Huimin; Liu Shiyuan; Li Chengzhou; Zhang Chenshi; Tao Zhiwei
Objective: To evaluate the feasibility on the investigation of bronchogenic adenocarcinoma angiogenesis with dynamic multi-slice spiral computed tomography (MSCT) . Methods: 27 patients with bronchogenic adenocarcinomas (diameter ≤4 cm) underwent multi-location dynamic contrast material-enhanced (90 ml, 4 ml/s) serial CT. These dynamic images were processed with the 'time lapse' software and the 'functional CT' software. Peak heights of bronchogenic adenocarcinoma and the aorta, perfusion and mean transit time (MTT) were measured. Ratio of peak height of the bronchogenic adenocarcinoma to that of the aorta was calculated. Perfusion and mean transit time images were obtained. Results: Peak height of bronchogenic adenocarcinoma was (36.66 ± 13.53) HU. No statistically significant difference in the peak height was found between our results and the results of Ukihide et al (mean peak height 34.1 HU) (t =0.981, P = 0.335). Bronchogenic adenocarcinoma-to-aorta ratio was (15.72±4.66 )%. The difference in bronchogenic adenocarcinoma -to-aorta ratio between our results and the results of Zhang and Kono (mean malignant SPN-to-aorta ratio 14.6%) did not reach statistical significance (t=1.244, P=0.225). The mean perfusion value (3.278 ml·min - · kg -1 ) was in the range of that (1.36-2.98 ml·min -1 ·kg -1 ) measured with a single photon emission CT (SPECT). Mean transit time was (17.60 ± 4.52) s. Conclusion: It is feasible to investigate bronchogenic adenocarcinoma angiogenesis with dynamic MSCT
Full Text Available Yasushi Kono,1 Shota Fukuda,1 Akihisa Hanatani,2 Koki Nakanishi,2 Kenichiro Otsuka,2 Haruyuki Taguchi,1 Kenei Shimada2 1Department of Medicine, Osaka Ekisaikai Hospital, Osaka, Japan; 2Department of Internal Medicine and Cardiology, Osaka City University School of Medicine, Osaka, Japan Background: Remote ischemic conditioning (RIC is a treatment modality that suppresses inflammation and improves endothelial function, which are factors involved in the pathogenesis of heart failure (HF with reduced left ventricular ejection fraction. Coronary flow reserve (CFR is a physiological index of coronary microcirculation and is noninvasively measured by transthoracic Doppler echocardiography (TTDE. This study aimed to investigate the effects of RIC on CFR in healthy subjects and patients with HF, through the assessment by TTDE. Methods: Ten patients with HF with left ventricular ejection fraction of less than 40%, and ten healthy volunteers were enrolled in this study. RIC treatment was performed twice a day for 1 week. Our custom-made RIC device was programmed to automatically conduct 4 cycles of 5 minutes inflation and 5 minutes deflation of a blood pressure cuff to create intermittent arm ischemia. CFR measurements and laboratory tests were examined before, and after 1 week of RIC treatment. Results: One week of RIC treatment was well tolerated in both groups. RIC treatment increased CFR from 4.0±0.9 to 4.6±1.3 (mean ± standard deviation in healthy subjects (P=0.02, and from 1.9±0.4 to 2.3±0.7 in patients with HF (P=0.03, respectively. Systolic blood pressure in healthy subjects, and heart rate in HF patients decreased after RIC treatment (both P<0.01. Conclusion: This study demonstrated that a 1 week course of RIC treatment improved coronary microcirculation in healthy subjects and patients with HF associated with reduced left ventricular ejection fraction. Keyword: echocardiography, coronary flow reserve, heart failure, preconditioning
Cerdà, Artemi; Bagarello, Vincenzo; Iovino, Massimo; Ferro, Vito; Keesstra, Saskia; Rodrigo-Comino, Jesús; García Diaz, Andrés; di Prima, Simone
Infiltration is the key component of the hydrological cycle (Cerdà, 1999; Bagarello et al.,, 2014; Zema et al., 2016). Infiltration determines the partitioning of rainfall into runoff and subsurface flow (Cerdà, 1996; Bagarello et al., 2006; Wang et al., 2016). In the Mediterranean, agriculture resulted in the degradation of the soil structure, reduction of the organic matter and increase in the soil losses (Cerdà et al., 2009; Laudicina et al., 2015; Iovino et al., 2016; Willaarts et al., 2016). There is an urgent need to restore the agriculture soils to avoid floods, reduce the carbon emissions and avoid reservoir siltation (Aksakal et al., 2016; Ben Slimane et al., 2016; Yagüe et al., 2016). Catch Crops are widespread used due to their impact on the soil fertility (Mwango et al., 2016; Nishigaki et al., 2016 ; Nawaz et al., 2016). Catch crops also increase the amount of organic matter but little is known about the effect on soil infiltration. Two paired plots were selected in Les Alcusses (Moixent municipality) in Eastern Iberian Peninsula to compare the infiltration rates between a 8-years catch crop (Vicia sp) with a control (plough) soil. The measurements were carried out by means of ring infiltrometer in August 2014 and December 2014 under dry and wet conditions (Cerdà, 2001; Di Prima et al., 2016). The results show that the steady-state infiltration rates were 1.8 higher during the summer period, and that the catch crops did not increase the infiltration rates. Acknowledgements The research leading to these results has received funding from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement n 603498 (RECARE project) and the CGL2013- 47862-C2-1-R and CGL2016-75178-C2-2-R national research projects. References Aksakal, E. L., Sari, S., & Angin, I. (2016). Effects of vermicompost application on soil aggregation and certain physical properties. Land Degradation and Development, 27(4), 983-995. doi:10.1002/ldr.2350
Keesstra, Saskia; Jordán, Antonio; Novara, Agata; Taguas, Tani; Pereira, Paulo; Brevik, Eric C.; Cerdà, Artemi
Soil erosion in orchards and vineyards has been found non-sustainable due to bare soils due to the use of herbicides and tillage (Novara et al., 2011; Taguas et al., 2015; Ochoa et al., 2016; Rodrigo Comino et al., 2016a; 2016b; 2016c). Citrus plantations in sloping terrains are also non-sustainable from the soil erosion point of view due high erosion rates and the damage caused on infra-structures (Cerdà et al., 2009; 2009b; Cerdà et al., 2011; Pereira et al., 2015). This is not uncommon in Mediterranean type Ecosystems (Cerdà et al., 2010) but there is a need to reduce the soil and water losses to achieve sustainability (Brevik et al., 2015; Keesstra et al., 2016). The use of mulches, geotextiles, catch crops, and vegetation was found to be very successful as a sustainable strategy to reduce the soil losses (Giménez Morera et al., 2010; Mwango et al., 2016; Nawaz et al., 2016; Nishigaki et al., 2016; Prosdocimi et al., 2016). Nowadays, chipped branches are applied in orchards and vineyards because of European subsidies; however little scientific data is available on the impact of the chipped branches mulch on soil erosion. In an orange plantation in Eastern Valencia, at the L'Alcoleja experimental station the impact of these chipped branches was tested under 45 mm h-1 rainfall simulations on laboratory plots of 0.5 m2 under with different covers of chipped branches. The results show that with a cover of 20 % with chipped branches soil erosion reduces by 78 %. Acknowledgements The research leading to these results has received funding from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement 603498 (RECARE project) and the CGL2013- 47862-C2-1-R and CGL2016-75178-C2-2-R national research projects. References Brevik, E. C., Cerdà, A., Mataix-Solera, J., Pereg, L., Quinton, J. N., Six, J., and Van Oost, K. 2015. The interdisciplinary nature of SOIL, SOIL, 1, 117-129, doi:10.5194/soil-1-117-2015, Cerdà, A. and M. F. Jurgensen
Eugene T Richardson
Full Text Available Evidence for minimally symptomatic Ebola virus (EBOV infection is limited. During the 2013-16 outbreak in West Africa, it was not considered epidemiologically relevant to published models or projections of intervention effects. In order to improve our understanding of the transmission dynamics of EBOV in humans, we investigated the occurrence of minimally symptomatic EBOV infection in quarantined contacts of reported Ebola virus disease cases in a recognized 'hotspot.'We conducted a cross-sectional serosurvey in Sukudu, Kono District, Sierra Leone, from October 2015 to January 2016. A blood sample was collected from 187 study participants, 132 negative controls (individuals with a low likelihood of previous exposure to Ebola virus, and 30 positive controls (Ebola virus disease survivors. IgG responses to Ebola glycoprotein and nucleoprotein were measured using Alpha Diagnostic International ELISA kits with plasma diluted at 1:200. Optical density was read at 450 nm (subtracting OD at 630nm to normalize well background on a ChroMate 4300 microplate reader. A cutoff of 4.7 U/mL for the anti-GP ELISA yielded 96.7% sensitivity and 97.7% specificity in distinguishing positive and negative controls. We identified 14 seropositive individuals not known to have had Ebola virus disease. Two of the 14 seropositive individuals reported only fever during quarantine while the remaining 12 denied any signs or symptoms during quarantine.By using ELISA to measure Zaire Ebola virus antibody concentrations, we identified a significant number of individuals with previously undetected EBOV infection in a 'hotspot' village in Sierra Leone, approximately one year after the village outbreak. The findings provide further evidence that Ebola, like many other viral infections, presents with a spectrum of clinical manifestations, including minimally symptomatic infection. These data also suggest that a significant portion of Ebola transmission events may have gone
Vesel, Linda; Waller, Kathryn; Dowden, Justine; Fotso, Jean Christophe
In low- and middle-income countries, a shortage of properly trained, supervised, motivated and equitably distributed health workers often hinder the delivery of lifesaving interventions. Various health workforce bottlenecks can be addressed by tackling well-being and interpersonal relationships of health workers with their colleagues and clients. This paper uses data from the Helping Health Workers Cope (HHWC) project in a rural district of Sierra Leone to achieve three objectives. First, we describe the effect of counseling and psychosocial training on coping skills, stress levels, and provider-provider and provider-client relationships. Second, we examine whether a change in coping skills is associated with a change in relationships. Finally, we qualitatively identify key ways through which the uptake of coping skills is linked to a change in relationships. The HHWC project was implemented from February 2012 to June 2013 in Kono district in the Eastern province of Sierra Leone, with the neighboring district of Tonkolili selected as the control site. The evaluation followed a mixed-methods approach, which included a quantitative survey, in-depth interviews and focus group discussions with health workers and clients. Mean values of the variables of interest were compared across sub-populations, and correlation analyses were performed between changes in coping skills, stress levels, and changes in relationships. Overall, the results demonstrate that the HHWC intervention had a positive effect on coping skills, stress levels and provider-provider and provider-client relationships. Furthermore, associations were observed between changes in coping skills and changes in relationships as well as changes in stress management skills and changes in relationships. Psychosocial education can have major impacts on health worker well-being and the quality of health care delivery. Integrating psychosocial counseling and training interventions into health worker pre-service and
Frederico Aisc Carvalho
Full Text Available Este artigo aborda a construção do conhecimento segundo a perspectiva de duas ciências: a Psicologia do desenvolvimento e a Ciência da Informação. A abordagem da Psicologia privilegia os estudos dos construtivistas, especialmente Jean Piaget e Vygotsky, que analisaram como se desenvolve o raciocínio lógico desde os primeiros anos da criança até a maturidade alcançada ao final da adolescência. A abordagem da Ciência da Informação privilegiou os estudos relacionados à Gestão do Conhecimento, principalmente a ótica de Nonaka e Kono sobre as transformações do conhecimento tácito em explícito e vice-versa, em um processo de construção de conhecimento que passa pelo indivíduo, por grupos e organizações. Para ilustrar esse processo, especialmente nas crianças, integra o artigo uma pesquisa desenvolvida por Carvalho (2011, que procurou identificar a influência da propaganda sobre a construção do conhecimento das crianças na faixa de 5 a 9 anos, período em que está se estruturando o estágio de desenvolvimento denominado operatório-concreto. Os resultados apontaram que a mídia influencia significativamente as crianças e é responsável pelo conhecimento que elas adquirem da realidade, levando-as a preferirem comprar a brincar, preferirem ir a shoppings a parques e a identificar produtos de tecnologia avançada e a desejá-los como presentes. Como conclusão, o artigo realça a importância dos meios de comunicação para a construção do conhecimento e alerta para a necessidade de se adotarem situações que despertem a criança para a formulação de respostas que exijam raciocínio superior, além de chamar a atenção para a necessidade de uma ética na veiculação da informação que se destina a crianças e adolescentes.
Cerdà, Artemi; Nadal-Romero, Estela; Brevik, Eric C.; Pulido, Manuel; Maestre, Fermando T.; Taguas, Tani; Novara, Agata; Keesstra, Saskia; Cammeraat, Erik; Parras-Alcantara, Luis
The main factor controlling soil erosion is vegetation cover (Cerdà and Doerr, 2005; Van Eck et al., 2016; van Hall et al., 2017). However, due to the removal of the vegetation in agricultural fields and the increase in soil erosion rates other factors arise as keys to control soil erosion rates and mechanisms (Ochoa-Cueva et al., 2016; Rodrigo Comino et al., 2016). Soil erosion rates in olive plantations are high due to the lack of vegetation cover as a consequence of intensive tillage and herbicides abuse (Taguas et al., 2015; Parras-Alcantara et al., 2016; Zema et al., 2016). This is also found in vineyards and other orchards around the world (Prosdocimi et al., 2016; Rodrígo Comino et al., 2016), and the reason to look for sustainable management techniques such as geotextiles, mulches or catch crops that will stop the accelerated soil erosion (Giménez Morera et al., 2010; Mwango et al., 2016; Nawaz et al., 2016a; 2016b; Nishigaki et al., 2016). All these management techniques are difficult to apply and have high costs. Natural solutions such as weeds to provide cover are very efficient and have no cost (Cerdà et al., 2016; Keesstra et al., 2016) and they can be adapted to the management of the farmers. In olive orchards under herbicide treatment there is a natural growth of mosses and the development of a litter layer composed of olive leaves. There is also burrowing by wild boars that "ploughs" the soil. This research evaluates the impact of the three items above on soil erosion. The measurements were carried out using simulated rainfall experiments over an area of 0.25 m2 at a rainfall rate of 55 mm h-1 during one hour (Cerdà, 1996; Prosdocimi et al., 2017) on 15 plots of mosses, 15 wild boar burrowed surfaces and 15 leaf covered surfaces during the winter of 2015. The soil erosion rates were 34 times greater in the wild boar burrowed soils, meanwhile the litter and mosses covered soils showed similar erosional responses and the soil erosion rates were
Oncology. JMAJ 54(1: 44–46, 20114.Hildebrandt B, Wust P, Ahlers O, et al. The cellular and molecular basis of hyperthermia. Critical Reviews in Oncology/Hematology 2002; 43(1:33–56.5.Levin WP, Kooy H, Loeffler JS, DeLaney TF. Proton beam therapy. Br J Cancer.2005; 93(8:849-54. 6.Widakowich C, de Castro G Jr, de Azambuja E, Dinh P, Awada A. Review: side effects of approved molecular targeted therapies in solid cancers. Oncologist. 2007; 12(12:1443-55.7.Egawa K. Immuno-cell therapy of cancer in Japan. Anticancer Res. 2004;24(5C:3321-6. 8.Takayama T, Sekine T, Makuuchi M, Yamasaki S, Kosuge T, Yamamoto J, Shimada K, Sakamoto M, Hirohashi S, Ohashi Y, Kakizoe T. Adoptive immunotherapy to lower postsurgical recurrence rates of hepatocellular carcinoma: a randomised trial. Lancet. 2000; 356(9232:802-7. 9.Kimura H, Yamaguchi Y. A phase III randomized study of interleukin-2 lymphokine-activated killer cell immunotherapy combined with chemotherapy or radiotherapy after curative or noncurative resection of primary lung carcinoma. Cancer. 1997;80(1:42-9. 10.Kono K, Takahashi A, Ichihara F, Amemiya H, Iizuka H, Fujii H, Sekikawa T, Matsumoto Y: Prognostic significance of adoptive immunotherapy with tumor-associated lymphocytes in patients with advanced gastric cancer: a randomized trial. Clin Cancer Res. 2002; 8: 1767-71. 11.Fujita K, Ikarashi H, Takakuwa K, Kodama S, Tokunaga A, Takahashi T, Tanaka K. Prolonged disease-free period in patients with advanced epithelial ovarian cancer after adoptive transfer of tumor-infiltrating lymphocytes. Clin Cancer Res. 1995; 1(5:501-7.12.Goto S, Shirotani N, Hatakeyama M, Tagami C, Arakawa H, Kuwata E, Noguchi K, Egawa K. Clinical benefit of non-toxic therapy in patients with advanced cancer (opinion. Anticancer Res. 2002; 22(4:2461-4.
Full Text Available ŽMOGŲ APIBŪDINANTYS LIETUVIŠKI SKOLINIAI LIETUVOS LENKŲ TARMĖSE. SEMANTINIS IR ETNOLINGVISTINIS ASPEKTASSantraukaLietuvos lenkų tarmėse į žmogaus semantinį lauką patenkantys lituanizmai sudaro apie 24 procentus skolinių iš lietuvių kalbos. Ypač gausūs emocionalizmai ir ekspresyvizmai, pasitelkiami žmogui įvertinti tais atvejais, kai šis neatitinka tam tikroje socialinėje grupėje įsigalėjusių normų ir grožio kanono.Kai kurie tirti leksikos vienetai yra bendri tarminei ir šnekamajai lenkų kalbai bei lietuvių kalbai, (pvz., dryblas „aukštas žmogus“, tarmėse dar ir „žioplys“, liet. dribla, driblia; kurdupel, kurdupelek „žemo ūgio žmogus“, liet. kurdupelis, kartupelis „bulvė; neūžauga, susitraukęs žmogus“; taip pat rasta labai išplitusių žodžių, vartojamų lenkų kalbos tarmėse Lietuvoje ir baltarusių bei rusų tarmėse (pvz., kurstać ir iš šio žodžio sudarytos priešdėlių pod-, wy- (pa-, iš- formos, kurių reikšmė „raginti, skatinti“, balt. крстаць iš liet. kurstyti „dėti į ugnį kuro“, prk. „raginti, skatinti, žadinti, įkalbinėti, siundyti“. Šie lituanizmai yra prigiję slavų kalbose ir labai praverčia įvairių žmogaus išvaizdos ir psichikos aspektų konceptualizavimui.Aptariamas žodyno sluoksnis semantiškai gana įvairus. Čia randama stilistiškai konotuotų žodžių, kuriais žmogus priskiriamas tam tikrai kategorijai pagal jo kūno ypatumus: a nuo normos nukrypstantį ūgį ir akivaizdžius kūno defektus (pvz., kliszawy „šleivas, šleivakojis“, kupraty „kuprotas“; b vaikščiojimo būdą (tupotać / tupiniać (tupenti „eiti smulkiais žingsneliais, bidzenti“; c aplaidžią išvaizdą (murziak, liet. murzius „išsitepęs, nešvarus (apie vaiką“, sutra, liet. sutra, „netvarkinga, nevalyva moteris“ ir kt. Išskirtini ir žmogaus proto gebėjimus pagal jo elgesio racionalumą vertinantys žodžiai (kiemny
A team of radio astronomers has used the National Science Foundation's Very Long Baseline Array (VLBA) to make the most accurate measurement ever made of the distance to a faraway galaxy. Their direct measurement calls into question the precision of distance determinations made by other techniques, including those announced last week by a team using the Hubble Space Telescope. The radio astronomers measured a distance of 23.5 million light-years to a galaxy called NGC 4258 in Ursa Major. "Ours is a direct measurement, using geometry, and is independent of all other methods of determining cosmic distances," said Jim Herrnstein, of the National Radio Astronomy Observatory (NRAO) in Socorro, NM. The team says their measurement is accurate to within less than a million light-years, or four percent. The galaxy is also known as Messier 106 and is visible with amateur telescopes. Herrnstein, along with James Moran and Lincoln Greenhill of the Harvard- Smithsonian Center for Astrophysics; Phillip Diamond, of the Merlin radio telescope facility at Jodrell Bank and the University of Manchester in England; Makato Inoue and Naomasa Nakai of Japan's Nobeyama Radio Observatory; Mikato Miyoshi of Japan's National Astronomical Observatory; Christian Henkel of Germany's Max Planck Institute for Radio Astronomy; and Adam Riess of the University of California at Berkeley, announced their findings at the American Astronomical Society's meeting in Chicago. "This is an incredible achievement to measure the distance to another galaxy with this precision," said Miller Goss, NRAO's Director of VLA/VLBA Operations. "This is the first time such a great distance has been measured this accurately. It took painstaking work on the part of the observing team, and it took a radio telescope the size of the Earth -- the VLBA -- to make it possible," Goss said. "Astronomers have sought to determine the Hubble Constant, the rate of expansion of the universe, for decades. This will in turn lead to an
Ishioka, Sachio; Fujikawa, Kazuo
.]. Coalescence and rearrangement of vortices in mesoscopic superconductors / A. Kanda ... [et al.]. Superconductivity in topologically nontrivial spaces / M. Hayashi ... [et al.]. DC-SQUID ratchet using atomic point contact / Y. Ootuka, H. Miyazaki, A. Kanda. Superconducting wire network under spatially modulated magnetic field / H. Sano ... [et al.]. Simple and stable control of mechanical break junction for the study of superconducting atomic point contact / H. Miyazaki ... [et al.]. Critical currents in quasiperiodic pinning arrays: one-dimensional chains and Penrose lattices / V. R. Misko, S. Savel'ev, F. Nori. Macroscopic quantum tunneling in high-Tc superconductor Josephson junctions / S. Kawabata -- Novel properties of carbon nanotubes. Carbon nanotubes and unique transport properties: importance of symmetry and channel number / T. Ando. Optical processes in single-walled carbon nanotubes threaded by a magnetic flux / J. Kono ... [et al.]. Non-equilibrium transport through a single-walled carbon nanotube with highly transparent coupling to reservoirs / P. Recher, N. Y. Kim, Y. Yamamoto -- Novel properties of nano-systems. Transport properties in low dimensional artificial lattice of gold nano-particles / S. Saito ... [et al.]. First principles study of dihydride-chain structures on H-terminated Si(100) surface / Y. Suwa ... [et al.]. Electrical property of Ag nanowires fabricated on hydrogen-terminated Si(100) surface / M. Fujimori, S. Heike, T. Hashizume. Effect of environment on ionization of excited atoms embedded in a solid-state cavity / M. Ando ... [et al.]. Development of universal virtual spectroscope for optoelectronics research: first principles software replacing dielectric constant measurements / T. Hamada ... [et al.]. Quantum Nernst effect / H Nakamura, N. Hatano, R. Shirasaki -- Precise measurements. Quantum phenomena visualized using electron waves / A. Tonomura. An optical lattice clock: ultrastable atomic clock with engineered perturbation / H. Katori
experienced. An increase in awareness about this least toxic method of Cancer treatment among physicians and the public for an early referral is necessary. Further studies on prevention of cancer using in vitro expanded autologous immune cells are underway. References: 1.Takayama T, Sekine T, Makuuchi M, Yamasaki S, Kosuge T, Yamamoto J, Shimada K, Sakamoto M, Hirohashi S, Ohashi Y, Kakizoe T. Adoptive immunotherapy to lower postsurgical recurrence rates of hepatocellular carcinoma: a randomised trial. Lancet. 2000 ;356(9232:802-7. 2.Kimura H, Yamaguchi Y. A phase III randomized study of interleukin-2 lymphokine-activated killer cell immunotherapy combined with chemotherapy or radiotherapy after curative or noncurative resection of primary lung carcinoma. Cancer. 1997;80(1:42-9. 3.Kono K, Takahashi A, Ichihara F, Amemiya H, Iizuka H, Fujii H, Sekikawa T, Matsumoto Y: Prognostic significance of adoptive immunotherapy with tumor-associated lymphocytes in patients with advanced gastric cancer: a randomized trial. Clin Cancer Res. 2002; 8 : 1767-71. 4.Fujita K, Ikarashi H, Takakuwa K, Kodama S, Tokunaga A, Takahashi T, Tanaka K. Prolonged disease-free period in patients with advanced epithelial ovarian cancer after adoptive transfer of tumor-infiltrating lymphocytes. Clin Cancer Res. 1995;1(5:501-7.5.Sivaraman G, Pandian A, Baskar S, Senthil KR, Senthilnagarajan R, Dedeepiya V, Abraham S. Autologous Immune Enhancement therapy for advanced carcinoma of pancreas a case report. PASRM 2008-004. J Stem Cells Regen Med. 2008; 4(1:136.Damodar S, Terunuma H , Sheriff AK , Farzana L , Manjunath S , Senthilkumar R , Shastikumar G , Abraham S , Wang FS. Autologous Immune Enhancement Therapy (AIET for a Case of Acute Myeloid Leukemia (AML - Our Experience. PASRM 2006-001. J Stem Cells Regen Med. 2006, 1(1: 40-417.Takada M, Terunuma H, Deng X, Dewan MZ, Saji S, Kuroi K, Yamamoto N, Toi M. Refractory lung metastasis from breast cancer treated with multidisciplinary therapy including an