Surface functionalized thiol-ene waveguides for fluorescence biosensing in microfluidic devices

DEFF Research Database (Denmark)

Feidenhans'l, Nikolaj Agentoft; Lafleur, Josiane P.; Jensen, Thomas Glasdam

2013-01-01

-ene waveguides were fabricated from 40% excess thiol thiol-ene to ensure the presence of thiol functional groups at the surface of the waveguide. Biotin alkyne was photografted at specific locations using a photomask, directly at the interface between the microfluidic channel and the thiol-ene waveguide prior...

Fabrication and bonding of thiol-ene-based microfluidic devices

DEFF Research Database (Denmark)

Sikanen, Tiina M; Lafleur, Josiane P.; Moilanen, Maria-Elisa

2013-01-01

In this work, the bonding strength of microchips fabricated by thiol-ene free-radical polymerization was characterized in detail by varying the monomeric thiol/allyl composition from the stoichiometric ratio (1:1) up to 100% excess of thiol (2:1) or allyl (1:2) functional groups. Four different...... properties for each application. Here, a capillary electrophoresis separation is performed to demonstrate the attractive properties of stoichiometric thiol-ene microchips....

Evaluation and Control of Thiol-ene/Thiol-epoxy Hybrid Networks.

Science.gov (United States)

Carioscia, Jacquelyn A; Stansbury, Jeffrey W; Bowman, Christopher N

2007-03-08

The development of thiol-ene/thiol-epoxy hybrid networks offers the advantage of tailorable polymerization kinetics while producing a highly crosslinked, high T(g) polymer that has significantly reduced shrinkage stress. Stoichiometric mixtures of pentaerythritol tetra(3-mercaptopropionate) (PETMP)/triallyl-1,3,5-triazine-2,4,6-trione (TATATO) (thiol-ene, mixture 1) and PETMP/bisphenol a diglycidyl ether (BADGE) (thiol-epoxy, mixture 2) were prepared and hybrid mixtures of 75/25, 50/50, 25/75, and 10/90 w/w of mixtures 1 and 2 were polymerized using a combination of both radical and anionic initiation. The light exposure timing and the relative initiation conditions of the two types were used to control the order and relative rates of the radical and anionic polymerizations. The 50/50 w/w thiol-ene/thiol-epoxy hybrid material exhibited a final stress of only 0.2 MPa, which is 90 % lower than the stress developed in a control dimethacrylate resin. Kinetic analysis indicates composition affects network development in thiol-ene/thiol-epoxy hybrid networks and produces materials with robust mechanical properties.

Fabrication and bonding of thiol-ene-based microfluidic devices

International Nuclear Information System (INIS)

Sikanen, Tiina M; Moilanen, Maria-Elisa; Lafleur, Josiane P; Zhuang, Guisheng; Jensen, Thomas G; Kutter, Jörg P

2013-01-01

In this work, the bonding strength of microchips fabricated by thiol-ene free-radical polymerization was characterized in detail by varying the monomeric thiol/allyl composition from the stoichiometric ratio (1:1) up to 100% excess of thiol (2:1) or allyl (1:2) functional groups. Four different thiol-ene to thiol-ene bonding combinations were tested by bonding: (i) two stoichiometric layers, (ii) two layers bearing complementary excess of thiols and allyls, (iii) two layers both bearing excess of thiols, or (iv) two layers both bearing excess of allyls. The results showed that the stiffness of the cross-linked polymer plays the most crucial role regarding the bonding strength. The most rigid polymer layers were obtained by using the stoichiometric composition or an excess of allyls, and thus, the bonding combinations (i) and (iv) withstood the highest pressures (up to the cut-off value of 6 bar). On the other hand, excess of thiol monomers yielded more elastic polymer layers and thus decreased the pressure tolerance for bonding combinations (ii) and (iii). By using monomers with more thiol groups (e.g. tetrathiol versus trithiol), a higher cross-linking ratio, and thus, greater stiffness was obtained. Surface characterization by infrared spectroscopy confirmed that the changes in the monomeric thiol/allyl composition were also reflected in the surface chemistry. The flexibility of being able to bond different types of thiol-enes together allows for tuning of the surface chemistry to yield the desired properties for each application. Here, a capillary electrophoresis separation is performed to demonstrate the attractive properties of stoichiometric thiol-ene microchips. (technical note)

Investigations of thiol-modified phenol derivatives for the use in thiol-ene photopolymerizations.

Science.gov (United States)

Reinelt, Sebastian; Tabatabai, Monir; Fischer, Urs Karl; Moszner, Norbert; Utterodt, Andreas; Ritter, Helmut

2014-01-01

Thiol-ene photopolymerizations gain a growing interest in academic research. Coatings and dental restoratives are interesting applications for thiol-ene photopolymerizations due to their unique features. In most studies the relative flexible and hydrophilic ester derivative, namely pentaerythritoltetra(3-mercaptopropionate) (PETMP), is investigated as the thiol component. Thus, in the present study we are encouraged to investigate the performance of more hydrophobic ester-free thiol-modified bis- and trisphenol derivatives in thiol-ene photopolymerizations. For this, six different thiol-modified bis- and trisphenol derivatives exhibiting four to six thiol groups are synthesized via the radical addition of thioacetic acid to suitable allyl-modified precursors and subsequent hydrolysis. Compared to PETMP better flexural strength and modulus of elasticity are achievable in thiol-ene photopolymerizations employing 1,3,5-triallyl-1,3,5-triazine-2,4,6-trione (TATATO) as the ene derivative. Especially, after storage in water, the flexural strength and modulus of elasticity is twice as high compared to the PETMP reference system.

Investigations of thiol-modified phenol derivatives for the use in thiol–ene photopolymerizations

Science.gov (United States)

Reinelt, Sebastian; Tabatabai, Monir; Fischer, Urs Karl; Moszner, Norbert; Utterodt, Andreas

2014-01-01

Summary Thiol–ene photopolymerizations gain a growing interest in academic research. Coatings and dental restoratives are interesting applications for thiol–ene photopolymerizations due to their unique features. In most studies the relative flexible and hydrophilic ester derivative, namely pentaerythritoltetra(3-mercaptopropionate) (PETMP), is investigated as the thiol component. Thus, in the present study we are encouraged to investigate the performance of more hydrophobic ester-free thiol-modified bis- and trisphenol derivatives in thiol–ene photopolymerizations. For this, six different thiol-modified bis- and trisphenol derivatives exhibiting four to six thiol groups are synthesized via the radical addition of thioacetic acid to suitable allyl-modified precursors and subsequent hydrolysis. Compared to PETMP better flexural strength and modulus of elasticity are achievable in thiol–ene photopolymerizations employing 1,3,5-triallyl-1,3,5-triazine-2,4,6-trione (TATATO) as the ene derivative. Especially, after storage in water, the flexural strength and modulus of elasticity is twice as high compared to the PETMP reference system. PMID:25161731

Investigations of thiol-modified phenol derivatives for the use in thiol–ene photopolymerizations

Directory of Open Access Journals (Sweden)

Sebastian Reinelt

2014-07-01

Full Text Available Thiol–ene photopolymerizations gain a growing interest in academic research. Coatings and dental restoratives are interesting applications for thiol–ene photopolymerizations due to their unique features. In most studies the relative flexible and hydrophilic ester derivative, namely pentaerythritoltetra(3-mercaptopropionate (PETMP, is investigated as the thiol component. Thus, in the present study we are encouraged to investigate the performance of more hydrophobic ester-free thiol-modified bis- and trisphenol derivatives in thiol–ene photopolymerizations. For this, six different thiol-modified bis- and trisphenol derivatives exhibiting four to six thiol groups are synthesized via the radical addition of thioacetic acid to suitable allyl-modified precursors and subsequent hydrolysis. Compared to PETMP better flexural strength and modulus of elasticity are achievable in thiol–ene photopolymerizations employing 1,3,5-triallyl-1,3,5-triazine-2,4,6-trione (TATATO as the ene derivative. Especially, after storage in water, the flexural strength and modulus of elasticity is twice as high compared to the PETMP reference system.

Evaluation and Control of Thiol-ene/Thiol-epoxy Hybrid Networks

OpenAIRE

Carioscia, Jacquelyn A.; Stansbury, Jeffrey W.; Bowman, Christopher N.

2007-01-01

The development of thiol-ene/thiol-epoxy hybrid networks offers the advantage of tailorable polymerization kinetics while producing a highly crosslinked, high Tg polymer that has significantly reduced shrinkage stress. Stoichiometric mixtures of pentaerythritol tetra(3-mercaptopropionate) (PETMP)/triallyl-1,3,5-triazine-2,4,6-trione (TATATO) (thiol-ene, mixture 1) and PETMP/bisphenol a diglycidyl ether (BADGE) (thiol-epoxy, mixture 2) were prepared and hybrid mixtures of 75/25, 50/50, 25/75, ...

Rapid and simple preparation of thiol-ene emulsion-templated monoliths and their application as enzymatic microreactors

DEFF Research Database (Denmark)

Lafleur, Josiane P; Senkbeil, Silja; Novotny, Jakub

2015-01-01

A novel, rapid and simple method for the preparation of emulsion-templated monoliths in microfluidic channels based on thiol-ene chemistry is presented. The method allows monolith synthesis and anchoring inside thiol-ene microchannels in a single photoinitiated step. Characterization by scanning...... electron microscopy showed that the methanol-based emulsion templating process resulted in a network of highly interconnected and regular thiol-ene beads anchored solidly inside thiol-ene microchannels. Surface area measurements indicate that the monoliths are macroporous, with no or little micro...

Ene-Liis Semper : hindan päeva, kui teen ühte asja / Ene-Liis Semper ; interv. Jaanus Kulli

Index Scriptorium Estoniae

Semper, Ene-Liis, 1969-

2008-01-01

Teatri- ja videokunstnik Ene-Liis Semper oma elust ja tööst. Lisaks repliik "Parim päev on tööst prii päev" ja peagi Teater NO99s esietenduvast William Shakespeare'i lavastusest "Muinasjutuline "Perikles"

Aasta betoonehitise žürii kommentaarid võistlustöödele ja võitjaile / Eva Kiisler, Maritta Koivisto, Angel Andla...[jt.] ; intervjueerinud Mari Sarv ; kommenteerinud Mart Riikoja

Index Scriptorium Estoniae

2009-01-01

Konkursile "Aasta Betoonehitis 2008" annavad hinnangu Eva Kiisler (ajakirja "Ehitaja" peatoimetaja), Maritta Koivisto (Soome ajakirja "Betoni" peatoimetaja"), Angel Andla (Eesti Ehitusettevõtjate Liit), Heiki Meos (Eesti Ehitusinseneride Liit), Siim Sultson ("Äripäeva" ehitusvaldkonna toimetaja), Toomas Laur (Eesti Betooniühing), Ike Volkov (Eesti Arhitektide Liidu esimees), Mauno Inkinen (Eesti Projektbüroode Liit), Enno Rebane (Eesti Ehitusmaterjalide Tootjate Liidu tegevdirektor). Mart Riikoja žürii tööst

On the reaction of the nitroso group with olefins. Mechanisms of ene reactions

International Nuclear Information System (INIS)

Seymour, C.A.; Greene, F.D.

1982-01-01

Intra- and intermolecular isotope effects point to a two-step process for the reaction of pentafluoronitrosobenzene with tetramethylethylene to afford the ene product, rate-determining formation of an intermediate (for which the arizidine N-oxide is suggested) followed by C-H (or C-D) cleavage to the ene product

Antibiofouling hybrid dendritic Boltorn/star PEG thiol-ene cross-linked networks.

Science.gov (United States)

Bartels, Jeremy W; Imbesi, Philip M; Finlay, John A; Fidge, Christopher; Ma, Jun; Seppala, Jonathan E; Nystrom, Andreas M; Mackay, Michael E; Callow, James A; Callow, Maureen E; Wooley, Karen L

2011-06-01

A series of thiol-ene generated amphiphilic cross-linked networks was prepared by reaction of alkene-modified Boltorn polyesters (Boltorn-ene) with varying weight percent of 4-armed poly(ethylene glycol) (PEG) tetrathiol (0-25 wt%) and varying equivalents of pentaerythritol tetrakis(3-mercaptopropionate) (PETMP) (0-64 wt%). These materials were designed to present complex surface topographies and morphologies, with heterogeneity of surface composition and properties and robust mechanical properties, to serve as nontoxic antibiofouling coatings that are amenable to large-scale production for application in the marine environment. Therefore, a two-dimensional matrix of materials compositions was prepared to study the physical and mechanical properties, over which the compositions spanned from 0 to 25 wt% PEG tetrathiol and 0-64 wt% PETMP (the overall thiol/alkene (SH/ene) ratios ranged from 0.00 to 1.00 equiv), with both cross-linker weight percentages calculated with respect to the weight of Boltorn-ene. The Boltorn-ene components were prepared through the esterification of commercially available Boltorn H30 with 3-butenoic acid. The subsequent cross-linking of the Boltorn-PEG-PETMP films was monitored using IR spectroscopy, where it was found that near-complete consumption of both thiol and alkene groups occurred when the stoichiometry was ca. 48 wt% PETMP (0.75 equiv SH/ene, independent of PEG amount). The thermal properties of the films showed an increase in T(g) with an increase in 4-armed PEG-tetrathiol wt%, regardless of the PETMP concentration. Investigation of the bulk mechanical properties in dry and wet states found that the Young's modulus was the greatest at 48 wt% PETMP (0.75 equiv of SH/ene). The ultimate tensile strength increased when PETMP was constant and the PEG concentration was increased. The Young's modulus was slightly lower for wet films at constant PEG or constant PETMP amounts, than for the dry samples. The nanoscopic surface features were

A Study of Functional Polymer Colloids Prepared Using Thiol-Ene/Yne Click Chemistry

Science.gov (United States)

Durham, Olivia Z.

This project demonstrates the first instance of thiol-ene chemistry as the polymerization method for the production of polymer colloids in two-phase heterogeneous suspensions, miniemulsions, and emulsions. This work was also expanded to thiol-yne chemistry for the production of polymer particles containing increased crosslinking density. The utility of thiol-ene and thiol-yne chemistries for polymerization and polymer modification is well established in bulk systems. These reactions are considered 'click' reactions, which can be defined as processes that are both facile and simple, offering high yields with nearly 100% conversion, no side products, easy product separation, compatibility with a diverse variety of commercially available starting materials, and orthogonality with other chemistries. In addition, thiol-ene and thiol-yne chemistry follow a step-growth mechanism for the development of highly uniform polymer networks, where polymer growth is dependent on the coupling of functional groups. These step-growth polymerization systems are in stark contrast to the chain-growth mechanisms of acrylic and styrenic monomers that have dominated the field of conventional heterogeneous polymerizations. Preliminary studies evaluated the mechanism of particle production in suspension and miniemulsion systems. Monomer droplets were compared to the final polymer particles to confirm that particle growth occurred through the polymerization of monomer droplets. Additional parameters examined include homogenization energy (mechanical mixing), diluent species and concentration, and monomer content. These reactions were conducted using photoinitiation to yield particles in a matter of minutes with diameters in the size range of several microns to hundreds of microns in suspensions or submicron particles in miniemulsions. Improved control over the particle size and size distribution was examined through variation of reaction parameters. In addition, a method of seeded suspension

Surface modification of cyclomatrix polyphosphazene microsphere by thiol-ene chemistry and lectin recognition

International Nuclear Information System (INIS)

Chen, Chen; Zhu, Xue-yan; Gao, Qiao-ling; Fang, Fei; Huang, Xiao-jun

2016-01-01

Graphical abstract: A new synthetic route leading to polyphosphazene cyclomatrix microsphere with various functional groups has achieved via thiol-ene click modification. Herein, hexacholorocyclophosphazene (HCCP) crosslinked with bisphenol-S and 4,4′-diallyl bisphenol-S to generate broadly dispersed microspheres. Thiol-ene modification under UV irradiation not only presented high efficiency and flexibility for post-functionalization, but also imposed no harm on global morphology and crosslinked skeleton of such microspheres. - Highlights: • Functional polyphosphazene microspheres with high chemical flexibility were synthesized by thiol-ene modification. • Polyphosphazene microspheres possessed high thermal stability. • Glycosylated polyphosphazene microspheres showed affinity to lectin Con-A, which inferred potential application in biomedicine. - Abstract: A new synthetic route leading to functional polyphosphazene cyclomatrix microsphere has been developed via thiol-ene click modification. Hexacholorocyclophosphazene (HCCP) was crosslinked with both bisphenol-S and 4,4′-diallyl bisphenol-S to obtain vinyl polyphosphazene microspheres (VPZM) in order to ensure high crosslinking degree and introduce vinyl moieties. Compared to the microspheres obtained by HCCP and bisphenol-S, the size of VPZM was broadly dispersed from 400 nm to 1.40 μm. Thiol-ene click reactions were carried out to attach functional groups, such as glucosyl, carboxyl, ester and dodecyl groups onto polyphosphazene microspheres, which demonstrated no change in morphology and size after modification. Solid state NMR (SSNMR) and Fourier transform infrared spectoscopy (FT-IR) results showed that the vinyl moieties were introduced in the period of crosslinking and functionalization was also successful via click reactions. Moreover, the microspheres presented a little difference in thermal properties after modification. Concanavalin A (Con-A) fluorescent adsorption was also observed for

Surface modification of cyclomatrix polyphosphazene microsphere by thiol-ene chemistry and lectin recognition

Energy Technology Data Exchange (ETDEWEB)

Chen, Chen; Zhu, Xue-yan; Gao, Qiao-ling; Fang, Fei; Huang, Xiao-jun, E-mail: hxjzxh@zju.edu.cn

2016-11-30

Graphical abstract: A new synthetic route leading to polyphosphazene cyclomatrix microsphere with various functional groups has achieved via thiol-ene click modification. Herein, hexacholorocyclophosphazene (HCCP) crosslinked with bisphenol-S and 4,4′-diallyl bisphenol-S to generate broadly dispersed microspheres. Thiol-ene modification under UV irradiation not only presented high efficiency and flexibility for post-functionalization, but also imposed no harm on global morphology and crosslinked skeleton of such microspheres. - Highlights: • Functional polyphosphazene microspheres with high chemical flexibility were synthesized by thiol-ene modification. • Polyphosphazene microspheres possessed high thermal stability. • Glycosylated polyphosphazene microspheres showed affinity to lectin Con-A, which inferred potential application in biomedicine. - Abstract: A new synthetic route leading to functional polyphosphazene cyclomatrix microsphere has been developed via thiol-ene click modification. Hexacholorocyclophosphazene (HCCP) was crosslinked with both bisphenol-S and 4,4′-diallyl bisphenol-S to obtain vinyl polyphosphazene microspheres (VPZM) in order to ensure high crosslinking degree and introduce vinyl moieties. Compared to the microspheres obtained by HCCP and bisphenol-S, the size of VPZM was broadly dispersed from 400 nm to 1.40 μm. Thiol-ene click reactions were carried out to attach functional groups, such as glucosyl, carboxyl, ester and dodecyl groups onto polyphosphazene microspheres, which demonstrated no change in morphology and size after modification. Solid state NMR (SSNMR) and Fourier transform infrared spectoscopy (FT-IR) results showed that the vinyl moieties were introduced in the period of crosslinking and functionalization was also successful via click reactions. Moreover, the microspheres presented a little difference in thermal properties after modification. Concanavalin A (Con-A) fluorescent adsorption was also observed for

Episodic nature of the delta 4-ene and delta 5-ene steroidogenic pathways and their relationship to the adreno-gonadal axis in stallions.

Science.gov (United States)

Ganjam, V K

1979-01-01

Changes in the daily secretory patterns of testosterone and other 17 beta-hydroxyandrogen, total oestrogens and total corticoids were investigated in 7 stallions. Pulsatile fluctuations in plasma hormone levels were found in the serial blood samples collected hourly for 24 h in all animals. The plasma profiles indicated that corticoids, oestrogens and androgens were secreted episodically at all times in stallions. A significant correlation was observed between the precursor and products of delta 4-ene and delta 5-ene pathways and in inverse correlation (r = -0.68; P less than 0.01) was observed between total androgens and total corticoids. The significance of these episodic fluctuations of the major steroid hormones are discussed.

Kandidaadid : Ene Ergma versus Toomas Hendrik Ilves

Index Scriptorium Estoniae

2006-01-01

Artiklis vastatakse küsimustele, kes oleksid Kadriorus Ene Ergma ja Toomas Hendrik Ilvese nõunikud, millist sõnumit kannaks nende esimene iseseisvuspäeva kõne, kuidas nad tähistaksid oma võitu presidendivalimistel, kellele nad annaksid Maarjamaa Risti, kuhu nad teeksid oma esimese välisvisiidi

Tandem Wittig-ene reaction approach to kainic acid

Digital Repository Service at National Institute of Oceanography (India)

Majik, M.S.; Parameswaran, P.S.; Tilve, S.G.

The first example of a tandem Wittig-intramolecular ene reaction approach and its application toward the synthesis of kainic acid is reported. The synthetic pathway involves conversion of prenyl bromide into phosphorane 3, followed by one-pot Wittig...

Functionalization of embedded thiol-ene waveguides for evanescent wave induced fluorescence detection in a microfluidic device

DEFF Research Database (Denmark)

Feidenhans'l, Nikolaj Agentoft; Jensen, Thomas Glasdam; Lafleur, Josiane P.

2013-01-01

We demonstrate the use of functional surface groups inherently present on off-stoichiometric thiol−ene polymers, for site-specific immobilization of biomolecules and detection by evanescent wave-induced fluorescence. An optofluidic chip featuring an embedded thiol−ene waveguide was selectively...... functionalized with biotin using photografting. The biotin was used for immobilization of fluorescently labelled streptavidin, and experiments revealed a linear correlation between streptavidin concentration and fluorescent intensity. To further demonstrate the attractiveness of using thiol−ene for optofluidic...

Investigations of thiol-modified phenol derivatives for the use in thiol–ene photopolymerizations

OpenAIRE

Sebastian Reinelt; Monir Tabatabai; Urs Karl Fischer; Norbert Moszner; Andreas Utterodt; Helmut Ritter

2014-01-01

Summary Thiol–ene photopolymerizations gain a growing interest in academic research. Coatings and dental restoratives are interesting applications for thiol–ene photopolymerizations due to their unique features. In most studies the relative flexible and hydrophilic ester derivative, namely pentaerythritoltetra(3-mercaptopropionate) (PETMP), is investigated as the thiol component. Thus, in the present study we are encouraged to investigate the performance of more hydrophobic ester-free thiol-m...

An academic with ambition / Ene Ergma ; interv. Kadri Kukk

Index Scriptorium Estoniae

Ergma, Ene, 1944-

2006-01-01

Intervjuus Riigikogu asespiikriga käsitletakse kõrghariduse korraldust, professorite rohkust kõrgkoolides, võimalikku kandideerimist Tartu ülikooli rektori kohale, omandatud poliitilisi kogemusi ning ajude äravoolu Eestist. Ene Ergma CV

Sa uurisid ekspressionismi 1960ndatel ja 70ndatel... / Ene Lamp

Index Scriptorium Estoniae

Lamp, Ene

2005-01-01

2004. a. ilmunud raamatu "Ekspressionism" eest Eesti Kultuurkapitali suure kunstipreemia (100000 kr.) saanud Ene Lamp ekspressionismi tähenduse muutumiset, ekspressionismi rollist eesti kunstis, oma tulevikuplaanidest

Ene-Liiz Semper. Anton Litvin. Bogdan Mamonov

Index Scriptorium Estoniae

2005-01-01

Veebruaris Madridis toimunud Euroopa kunstilaada ARCO jaoks Vene saatkonna galerii poolt koostatud kunstinäitus TRINITY toimub nüüd Tallinnas Vene saatkonna galeriis. Kuraatorid Masha ja Andrei Melnikovid. Osalevad Ene-Liis Semper videoga ArtVideo, vene kunstnik Bogdan Mamonov maaliseeriaga "Ma kanoniseerisin oma sõpru" ja vene kunstnik Anton Litvin fotoprojektiga "Punktuatsioon". Madridis näitas Semper videot "Nimetu"

Proof of a conjecture of Colliot-Th\\'el\\`ene

OpenAIRE

Denef, Jan

2011-01-01

We prove a conjecture of Colliot-Th\\'el\\`ene that implies the Ax-Kochen Theorem on p-adic forms. We obtain it as an easy consequence of a diophantine excision theorem whose proof forms the body of the present paper.

preparation of bicyclic lactones using lewis acids catalyzed ene

African Journals Online (AJOL)

Administrator

The synthesis of the cis-fused bicyclic lactones relies extensively on the Lewis acid ... having an allylic hydrogen (an"ene") and a compound containing an electron .... observed that the lithium enolate obtained from 3-methyl-2(5H)- furanone ...

Preparation and Characterization of Fluorinated Hydrophobic UV-Crosslinkable Thiol-Ene Polyurethane Coatings

Directory of Open Access Journals (Sweden)

Wenjing Xia

2017-08-01

Full Text Available The polyurethane prepolymer terminated with a double bond was synthesized using isophorone diisocyanate (IPDI, hydroxyl terminated polybutadiene (HTPB, 1,4-butanediol (BDO, and 2-hydroxyethyl acrylate (HEA. Then, a series of innovative UV-curable polyurethane coatings were prepared by blending ene-terminated polyurethane, fluoroacrylate monomer, and multifunctional thiol crosslinker upon UV exposure. The incorporation of fluoroacrylate monomer and multifunctional thiols into polyurethane coatings significantly enhanced the hydrophobic property, mechanical property, pencil hardness, and glossiness of the polyurethane coatings. This method of preparing UV crosslinkable, hydrophobic polyurethane coatings based on thiol-ene chemistry exhibited numerous advantages over other UV photocuring systems.

ENE-Mates - A public information program for women

International Nuclear Information System (INIS)

Nagashima, Kyoko

1995-01-01

Japan depends on import for more than 80 percent of its total energy supply. Nuclear energy is one of the most promising alternatives to oil. It plays a significant role for energy supply in terms of reliability, economic viability and reduction of CO 2 emissions. In order to secure needed capacity, the Government concentrates its efforts on acquiring public acceptance of nuclear power as well as ensuring the safety of plants and improving plant capability and reliability. An opinion poll, done by the Japanese Government in Sep. of 1990, showed that 73.3 percent of man and 57.4 percent of women think that nuclear power is necessary to secure energy supply. Nuclear Power Engineering Corporation (NUPEC) employs various methods for information services arid, in particular, electric power generation including nuclear with an assignment from the Japanese Government. Public information activities by the Nuclear Power Engineering Corporation (NUPEC) are as follows: a) Telephone QA service to respond to public inquiries; b) Publishing the 'Nuclear Newsletter' monthly and various brochures; c) Information service by personal computer network Atomnet concerning energy in general, and operation/trouble informations of nuclear plants; d) Distribution and service of personal computers to local governments offices/museums, etc., for users ranging from children to adults to gather nuclear related information; e) Organization of female monitors 'ENE-MATES' to have lecture meetings and site tours. ENE-MATES - A Public Information Program For Women. As a 1990 opinion poll shows, women's feelings about nuclear energy differ from that of men. Women are more sensitive and anxious than men on nuclear energy issues. To improve this situation several programs for women have been planned and implemented.'ENE-MATES' program is one of these cases. It's purpose is to encourage women, centering around house wives, to have unbiased understanding of energy-related issues

Novel Thiol-Ene Hybrid Coating for Metal Protection

Directory of Open Access Journals (Sweden)

Mona Taghavikish

2016-04-01

Full Text Available A novel hybrid anticorrosion coating with dual network of inorganic (Si–O–Si and organic bonds (C–S–C was prepared on metal through an in situ sol-gel and thiol-ene click reaction. This novel interfacial thin film coating incorporates (3-mercaptopropyl trimethoxysilane (MPTS and 1,4-di(vinylimidazolium butane bisbromide based polymerizable ionic liquid (PIL to form a thiol-ene based photo-polymerized film, which on subsequent sol-gel reaction forms a thin hybrid interfacial layer on metal surface. On top of this PIL hybrid film, a self-assembled nanophase particle (SNAP coating was employed to prepare a multilayer thin film coating for better corrosion protection and barrier performance. The novel PIL hybrid film was characterised for structure and properties using Fourier transform infrared spectroscopy (FTIR, differential scanning calorimetry (DSC, and thermogravimetric analysis (TGA. The corrosion protection performance of the multilayer coating was examined using potentiodynamic polarization and electrochemical impedance spectroscopy (EIS. The results reveal that this novel double layer coating on metal offers excellent protection against corrosion and has remarkably improved the barrier effect of the coating.

DFT Investigation of the Palladium-Catalyzed Ene-Yne Coupling

DEFF Research Database (Denmark)

Henriksen, Signe Teuber; Tanner, David Ackland; Skrydstrup, T.

2010-01-01

). Concerning chemoselectivity, the calculations also clarify why the ene-yne coupling is able to dominate over plausible alternative reaction pathways such as alkene homocoupiing and alkyne polymerization. The role of the phosphine ligand at various stages of the catalytic cycle has also been delineated....

Synthesis and characterization of thiol-ene functionalized siloxanes and evaluation of their polymerization kinetics, network properties, and dental applications

Science.gov (United States)

Cole, Megan A.

We explored formation-structure-property relationships in thiol-ene functionalized oligosiloxanes to create crosslinked networks. Specifically, nine oligomers were synthesized, three with thiol-functional silane repeats and three with allyl-functional silane repeats. Structural variations in each oligomer were systematically induced through the incorporation of non-reactive repeats bearing either diphenyl or di-n-octyl moieties, and the oligomer molecular weight was limited by the presence of monofunctional silane condensation species. The molecular weights and chain compositions of all oligomers were ascertained and subsequently used in the evaluation of network properties formed upon photopolymerization of thiol- and ene-functional reactants. Polymerization kinetics of the thiol-ene functionalized siloxanes were also investigated using photoinitiation owing to the spatial and temporal control afforded by this technique. In particular, the effects of the viscosity of the ene-functionalized oligomer and the degree of thiol functionalization on the observed polymerization rate were determined. Results showed that the speed of polymerization varied with changes to the rate-limiting step, which was heavily influenced by neighboring non-reactive functionalities. Moreover, the thiol-ene reaction was found to exhibity unimolecular termination exclusively in siloxane-based systems. Proposed use of the thiol-ene functionalized siloxane system as a dental impression material necessitated the development of a redox initiation scheme. Evaluation of the benzoylperoxide/dimethyl-p-toluidine redox pair in traditional systems showed bulk thiol-ene polymerizations comparable to photoinitiation with the added advantage of uninhibited depth control, as also demonstrated in small molecule thiol-ene coupling reactions initiated by this same redox system. Application of the redox pair to the siloxane system allowed for the viscoelastic properties as well as the feature replication

Preparation of Biomolecule Microstructures and Microarrays by Thiol–ene Photoimmobilization

NARCIS (Netherlands)

Weinrich, Dirk; Köhn, Maja; Jonkheijm, Pascal; Westerlind, Ulrika; Dehmelt, Leif; Engelkamp, Hans; Christianen, Peter C.M.; Kuhlmann, Jürgen; Maan, Jan C.; Nüsse, Dirk; Schröder, Hendrik; Wacker, Ron; Voges, Edgar; Breinbauer, Rolf; Kunz, Horst; Niemeyer, Christof M.; Waldmann, Herbert

2010-01-01

A mild, fast and flexible method for photoimmobilization of biomolecules based on the light-initiated thiol–ene reaction has been developed. After investigation and optimization of various surface materials, surface chemistries and reaction parameters, microstructures and microarrays of biotin,

Thiol-ene reaction as tool for crosslinking of polynorbornene micelles in the nanoscale

Science.gov (United States)

Rupp, Barbara; Bauer, Thomas; Slugovc, Christian

2009-08-01

The thiol-ene reaction is a established photoreaction of multifunctional thiols and enes. Virtually any type of ene will participate in a free radical polymerisation process with a thiol. An advantage over many other photochemical reactions is that the reaction proceeds almost as rapidly in ambient conditions as in inert atmosphere. In this work we introduce the UV-crosslinking of polynorbornenes made by ring opening metathesis polymerization making use of the residual double bond in the polymer backbone. The crosslinking experiments were done in thin films and were followed by FTIR measurements, to proof the accessibility of double-bonds in the polymers for the addition of the thiols. As a result of these pre-experiments we created flexible and light transmitting films. To further increase the scope of this reaction, amphiphilic block copolymers were prepared and used to form block copolymer micelles in a selective solvent, which were subsequently crosslinked with pentaerythritol tetra(3-mercaptopropionate) (PETMP). FT-IR, DLS and SEM-measurements were used to prove the successful crosslinking and thus nanoparticle formation.

Ene ja Tõnis Kask pole valikuga rahul / Tiit Tuumalu

Index Scriptorium Estoniae

Tuumalu, Tiit, 1971-

2003-01-01

Eesti Filmiajakirjanike Ühing andis auhinna Aasta film 2002 mängufilmile "Agent Sinikael" : režissöör Marko Raat. Viimane sai preemiaks 12 000 krooni. Auhinna rahastajad omanimelise fondi kaudu Eesti Rahvuskultuuri Fondi juures Ene ja Tõnis Kask peavad "Nimed marmortahvlil" väljajätmist isegi nominentide hulgast shokeerivaks

Orented immobilization of farnesylated proteins by the thiol-ene reaction

NARCIS (Netherlands)

Weinrich, Dirk; Lin, Po-Chiao; Jonkheijm, Pascal; Nguyen, Uyen T.T.; Schröder, Hendrik; Niemeyer, Christof M.; Alexandrov, Kirill; Goody, Roger; Waldmann, Herbert

2010-01-01

Anchoring the protein: Proteins were immobilized rapidly under mild conditions by thiol-ene photocoupling between S-farnesyl groups attached to a genetically encodable “CAAX-box” tetrapeptide sequence (A is aliphatic) at the C terminus of the protein and surface-exposed thiols (see scheme). This

Simple preparation of thiol-ene particles in glycerol and surface functionalization by thiol-ene chemistry (TEC) and surface chain transfer free radical polymerization (SCT-FRP)

DEFF Research Database (Denmark)

Hoffmann, Christian; Chiaula, Valeria; Yu, Liyun

2018-01-01

functionalization of excess thiol groups via photochemical thiol-ene chemistry (TEC) resulting in a functional monolayer. In addition, surface chain transfer free radical polymerization (SCT-FRP) was used for the first time to introduce a thicker polymer layer on the particle surface. The application potential...

Spray-deposition and photopolymerization of organic-inorganic thiol-ene resins for fabrication of superamphiphobic surfaces.

Science.gov (United States)

Xiong, Li; Kendrick, Laken L; Heusser, Hannele; Webb, Jamie C; Sparks, Bradley J; Goetz, James T; Guo, Wei; Stafford, Christopher M; Blanton, Michael D; Nazarenko, Sergei; Patton, Derek L

2014-07-09

Superamphiphobic surfaces, exhibiting high contact angles and low contact angle hysteresis to both water and low surface tension liquids, have attracted a great deal attention in recent years because of the potential of these materials in practical applications such as liquid-resistant textiles, self-cleaning surfaces, and antifouling/anticorrosion coatings. In this work, we present a simple strategy for fabricating of superamphiphobic coatings based on photopolymerization of hybrid thiol-ene resins. Spray-deposition and UV photopolymerization of thiol-ene resins containing hydrophobic silica nanoparticles and perfluorinated thiols provide a multiscale topography and low-energy surface that endows the surface with superamphiphobicity. The wettability and chemical composition of the surfaces were characterized by contact-angle goniometry and X-ray photoelectron spectroscopy, respectively. The hierarchical roughness features of the thiol-ene surfaces were investigated with field-emission scanning electron microscopy. Droplet impact and sandpaper abrasion tests indicate the coatings respectively possess a robust antiwetting behavior and good mechanical durability.

Fabrication of Biomolecule Microarrays Using Rapid Photochemical Surface Patterning in Thiol-Ene-Based Microfluidic Devices.

Science.gov (United States)

Jönsson, Alexander; Lafleur, Josiane P

2018-01-01

In many biochip applications, it is advantageous to be able to immobilize biomolecules at specific locations on the surface of solid supports. In this protocol, we describe a photochemical surface patterning procedure based on thiol-ene/yne photochemistry which allows for the simple and rapid selective patterning of biomolecules on thiol-ene solid supports. We describe the preparation of solid supports which are required for the immobilization, including porous monoliths, as well as two different immobilization schemes based on biotin-streptavidin interactions and covalent linkage via free amino groups respectively.

Vares ja kana : [valmid] / Ivan Krõlov ; tlk. Eduard Kansa, Mart Raud, Timotheos Kuusik, Johannes Semper, G. Õis, Arnold Tulik, Oskar Urgart, Jaan Kärner, Jakob Tamm, Erni Hiir

Index Scriptorium Estoniae

Krõlov, Ivan, 1768(1769)-1844

2006-01-01

Sisu: Vares ja Kana ; Moosekandid ; Vares ja Rebane ; Konn ja Härg ; Pirtsakas Näitsik ; Oraakel ; Rukkilill ; Tuli ja Metsatukk ; Hunt ja Talleke ; Pärdik ja Prillid ; Ahvid ; Tihane ; Eesel ; Kotkas ja Kanad ; Võimumees ja Mõttetark ; Koerte sõprus ; Kasujaotus ; Vaat ; Kvartett ; Teekäijad ja Koerad ; Hunt penilas ; Oja ; Rebane ja Mäger ; Rohutirts ja Sipelgas ; Luiskaja ; Kukk ja Pärlitera ; Jänes jahil ; Hunt ja Kägu ; Haug ja Kass ; Peremees ja Sulane ; Voor ; Elevant maavalitsejaks ; Eesel ja Ööbik ; Külamehe kimbatus ; Elevant ja Mops ; Hunt ja tema Kutsikas ; Kass ja Kokk ; Lõvi ja Sääsk ; Aednik ja Filosoof ; Haned ; Siga ; Vanamees ja kolm noorukit ; Kotkas ja Ämblik ; Lehed ja Juured ; Hunt ja Rebane ; Lohe ; Rästas ; Mehhaanik ; Trishka satter ; Tiik ja Jõgi ; Luik, Haug ja Vähk ; Erak ja Karu ; Mesilane ja Kärbsed ; Lõvi jahisaak ; Talupojad ja Jõgi ; Lilled ; Uudishimulik ; Kaastundlik Rebane ; Kogukonna koosolek ; Demjani kalasupp ; Tihane ja Tuvi ; Hiir ja Rott ; Peegel ja Ahv ; Sääsk ja Karjane ; Talupoeg ja Surm ; Hunt ja Karjased ; Lõvi ja Rebane ; Kamm ; Hunt ja Kurg ; Pilv ; Poiss ja Siug ; Maamees ja Siug ; Kägu ja Tuvike ; Kaks Vaati ; Töökas Karu ; Rebane ja Viinamarjad ; Karu võrgus ; Kirjamees ja Röövel ; Mölder ; Siga Tamme all ; Kärbes ja Mesilane ; Ämblik ja Mesilane ; Rebane ja Eesel ; Siug ja Talleke ; Ööbikud ; Peremes ja Lammas ; Kaks Külameest ; Kaks Koera ; Kass ja Ööbik ; Kalade tants ; Haug ; Habemenoad ; Hiired ; Hunt ja Kass ; Karjane ; Orav ; Damaskuse mõõk ; Koer ja Hobune ; Rebane ; Hundid ja Lambad ; Kägu ja Kukk

Ene-yne Cross-Metathesis for the Preparation of 2,3-Diaryl-1,3-dienes

Directory of Open Access Journals (Sweden)

Meriem K. Abderrezak

2017-11-01

Full Text Available Ene-yne cross-metathesis from alkynes and ethylene is a useful method to produce substituted conjugated butadiene derivatives. If this method has been used with aliphatic alkynes, it has however never been used starting from diarylacetylenes as internal alkynes. We show that the ene-yne cross-metathesis catalyzed by the second generation Hoveyda ruthenium catalyst provides the 2,3-diarylbuta-1,3-dienes under 3 atm of ethylene at 100 °C. The scope and limitations of the reaction have been evaluated starting from unsymmetrical functionalized diarylacetylene derivatives hence leading to unsymmetrical 2,3-diarylbuta-1,3-dienes in a straightforward and environmentally acceptable manner.

Evaluation of fracture toughness and mechanical properties of ternary thiol-ene-methacrylate systems as resin matrix for dental restorative composites.

Science.gov (United States)

Beigi, Saeed; Yeganeh, Hamid; Atai, Mohammad

2013-07-01

Study and evaluation of fracture toughness, flexural and dynamic mechanical properties, and crosslink density of ternary thiol-ene-methacrylate systems and comparison with corresponding conventional methacrylate system were considered in the present study. Urethane tetra allyl ether monomer (UTAE) was synthesized as ene monomer. Different formulations were prepared based on combination of UTAE, BisGMA/TEGDMA and a tetrathiol monomer (PETMP). The photocuring reaction was conducted under visible light using BD/CQ combination as photoinitiator system. Mechanical properties were evaluated via measuring flexural strength, flexural modulus and fracture toughness. Scanning electron microscopy (SEM) was utilized to study the morphology of the fractured specimen's cross section. Viscoelastic properties of the samples were also determined by dynamic mechanical thermal analysis (DMTA). The same study was performed on a conventional methacrylate system. The data were analyzed and compared by ANOVA and Tukey HSD tests (significance level=0.05). The results showed improvement in fracture toughness of the specimens containing thiol-ene moieties. DMTA revealed a lower glass transition temperature and more homogenous structure for thiol-ene containing specimens in comparison to the system containing merely methacrylate monomer. The flexural modulus and flexural strength of the specimens with higher thiol-ene content were lower than the neat methacrylate system. The SEM micrographs of the fractured surface of specimens with higher methacrylate content were smooth and mirror-like (shiny) which represent brittle fracture. The thiol-ene-methacrylate system can be used as resin matrix of dental composites with enhanced fracture toughness in comparison to the methacrylate analogous. Copyright © 2013 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

Chalcogenidobis(ene-1,2-dithiolate)molybdenum(IV) complexes (chalcogenide E = O, S, Se): probing Mo≡E and ene-1,2-dithiolate substituent effects on geometric and electronic structure.

Science.gov (United States)

Sugimoto, Hideki; Tano, Hiroyuki; Suyama, Koichiro; Kobayashi, Tomoya; Miyake, Hiroyuki; Itoh, Shinobu; Mtei, Regina P; Kirk, Martin L

2011-02-07

New square-pyramidal bis(ene-1,2-dithiolate)MoSe complexes, [Mo(IV)Se(L)(2)](2-), have been synthesised along with their terminal sulfido analogues, [Mo(IV)S(L)(2)](2-), using alkyl (L(C(4)H(8))), phenyl (L(Ph)) and methyl carboxylate (L(COOMe)) substituted dithiolene ligands (L). These complexes now complete three sets of Mo(IV)O, Mo(IV)S and Mo(IV)Se species that are coordinated with identical ene-1,2-dithiolate ligands. The [alkyl substituted Mo(S/Se)(L(C(4)H(8)))(2)](2-) complexes were reported in prior investigations (H. Sugimoto, T. Sakurai, H. Miyake, K. Tanaka and H. Tsukube, Inorg. Chem. 2005, 44, 6927, H. Tano, R. Tajima, H. Miyake, S. Itoh and H. Sugimoto, Inorg. Chem. 2008, 47, 7465). The new series of complexes enable a systematic investigation of terminal chalcogenido and supporting ene-1,2-dithiolate ligand effects on geometric structure, electronic structure, and spectroscopic properties. X-ray crystallographic analysis of these (Et(4)N)(2)[MoEL(2)] (E = terminal chalocogenide) complexes reveals an isostructural Mo centre that adopts a distorted square pyramidal geometry. The M≡E bond distances observed in the crystal structures and the ν(M≡E) vibrational frequencies indicate that these bonds are weakened with an increase in L→Mo electron donation (L(COOMe) < L(Ph) < L(C(4)H(8))), and this order is confirmed by an electrochemical study of the complexes. The (77)Se NMR resonances in MoSeL complexes appear at lower magnetic fields as the selenido ion became less basic from MoSeL(C(4)H(8)), MoSeL(Ph) and MoSeL(COOMe). Electronic absorption and resonance Raman spectroscopies have been used to assign key ligand-field, MLCT, LMCT and intraligand CT bands in complexes that possess the L(COOMe) ligand. The presence of low-energy intraligand CT transition in these MoEL(COOMe) compounds directly probes the electron withdrawing nature of the -COOMe substituents, and this underscores the complex electronic structure of square pyramidal bis(ene-1

Rapid photochemical surface patterning of proteins in thiol-ene based microfluidic devices

DEFF Research Database (Denmark)

Lafleur, Josiane P.; Kwapiszewski, Radoslaw; Jensen, Thomas Glasdam

2013-01-01

! 17 SH nm"2. Biotin alkyne was patterned directly inside thiol–ene microchannels prior to conjugation with fluorescently labelled streptavidin. The surface bound conjugates were detected by evanescent waveinduced fluorescence (EWIF), demonstrating the success of the grafting procedure and its...

Investigations of step-growth thiol-ene polymerizations for novel dental restoratives.

Science.gov (United States)

Lu, Hui; Carioscia, Jacquelyn A; Stansbury, Jeffery W; Bowman, Christopher N

2005-12-01

The goal of this work was to investigate the feasibility of formulating novel dental restorative materials that utilize a step-growth thiol-ene photopolymerization. Particularly, we are aiming to significantly reduce the polymerization shrinkage and shrinkage stress while retaining adequate physical properties as compared to current dimethacrylatre-based systems. The thiol-ene system is composed of a 4:3 molar mixture of triallyl-1,3,5-triazine-2,4,6-trione (TATATO) and pentaerythritol tetramercaptopropionate (PETMP). The simultaneous measurement of shrinkage stress and functional group conversion was performed. Solvent extraction of unreacted monomers and dynamic mechanical analysis on the polymer networks that were formed were also studied. Flexural strength was measured for both filled and unfilled PETMP/TATATO and Bis-GMA/TEGDMA systems. Photopolymerization of PETMP/TATATO occurs at a much higher rate, with the maximum polymerization rate six times faster, than Bis-GMA/TEGDMA cured under the identical conditions. The results from the simultaneous measurement of shrinkage stress and conversion showed that the onset of shrinkage stress coincides with the delayed gel point conversion, which is predicted to be 41% for the 3:4 stoichiometric PETMP/TATATO resin composition. The maximum shrinkage stress developed for PETMP/TATATO was about 0.4 MPa, which was only approximately 14% of the maximum shrinkage stress of the Bis-GMA/TEGDMA system. Adequate flexural strength and flexural modulus values were obtained for both filled and unfilled PETMP/TATATO systems. The dramatically reduced shrinkage stress, increased polymerization rate, significance increased functional group conversion, and decreased leachable species are all benefits for the use-of thiol-ene systems as potential dental restorative materials.

Heat- and light-induced thiol-ene oligomerization of soybean oil-based polymercaptan

Science.gov (United States)

Polymercaptanized soybean oil (PMSO), the product of a thiol-ene reaction between soybean oil and hydrogen sulfide, is a material of interest as a lubricant additive and polymer precursor. We investigated with gel permeation chromatography, nuclear magnetic resonance (one-dimensional and two-dimensi...

Patterned Hydrophilization of Nanoporous 1,2‐PB by Thiol‐ene Photochemistry

DEFF Research Database (Denmark)

Berthold, Anton; Sagar, Kaushal Shashikant; Ndoni, Sokol

2011-01-01

is monitored by FT‐IR, UV–Vis, contact angle, and gravimetry. Overall quantum yields are calculated for the two thiol‐ene “click” reactions in nano‐confinement, neatly revealing their chain‐like nature. Top–down photolithographic patterning is demonstrated, realizing hydrophilic nanoporous “corridors...

Photocured thiol-ene based optical fluorescence sensor for determination of gold(III)

Energy Technology Data Exchange (ETDEWEB)

Çubuk, Soner, E-mail: sonercubuk@marmara.edu.tr; Kahraman, Memet Vezir; Yetimoğlu, Ece Kök; Kenan, Sibel

2014-02-17

Graphical abstract: -- Highlights: •Photopolymerized fluorescence sensor for Au(III) analysis has been developed. •Preparation of polymeric sensor is simple and quick. •Fluorescence sensor used for analysis of Au(III) in real samples. -- Abstract: This study describes the preparation and the characterization of a new thiol-ene based polymeric fluorescence sensor by photo initiated polymerization of trimethylolpropane tris(3-mercaptopropionate), 2-hydroxyethylacrylate, and 2,4,6-triallyloxy-1,3,5-triazine which are used as monomers and also a photo initiator (2,2-dimethoxy-2-phenylacetophenone) for its usage as optical sensor for gold ions. The thiol-ene based polymeric membrane sensor was characterized by using attenuated total reflectance-fourier transform infrared spectroscopy (ATR-FTIR) and scanning electron microscopy (SEM). The response characteristics of the sensors including dynamic range, pH effect, response time, and the effect of foreign ions were investigated. Fluorescence spectra showed that the excitation/emission maxima of the membrane were at 379/425 nm, respectively.

Photocured thiol-ene based optical fluorescence sensor for determination of gold(III)

International Nuclear Information System (INIS)

Çubuk, Soner; Kahraman, Memet Vezir; Yetimoğlu, Ece Kök; Kenan, Sibel

2014-01-01

Graphical abstract: -- Highlights: •Photopolymerized fluorescence sensor for Au(III) analysis has been developed. •Preparation of polymeric sensor is simple and quick. •Fluorescence sensor used for analysis of Au(III) in real samples. -- Abstract: This study describes the preparation and the characterization of a new thiol-ene based polymeric fluorescence sensor by photo initiated polymerization of trimethylolpropane tris(3-mercaptopropionate), 2-hydroxyethylacrylate, and 2,4,6-triallyloxy-1,3,5-triazine which are used as monomers and also a photo initiator (2,2-dimethoxy-2-phenylacetophenone) for its usage as optical sensor for gold ions. The thiol-ene based polymeric membrane sensor was characterized by using attenuated total reflectance-fourier transform infrared spectroscopy (ATR-FTIR) and scanning electron microscopy (SEM). The response characteristics of the sensors including dynamic range, pH effect, response time, and the effect of foreign ions were investigated. Fluorescence spectra showed that the excitation/emission maxima of the membrane were at 379/425 nm, respectively

Rapid photochemical surface patterning of proteins in thiol-ene based microfluidic devices

DEFF Research Database (Denmark)

Lafleur, Josiane P.; Kwapiszewski, Radoslaw; Jensen, Thomas Glasdam

2012-01-01

” and “ene” monomers present in the microfluidic chip bulk material provides a simple and efficient way of tuning the chip’s surface chemistry. Here, thiol-ene chips displaying an excess of functional thiol groups at their surfaces are functionalized with biotin and streptavidin in a controlled fashion using...

Superhydrophobic hybrid inorganic-organic thiol-ene surfaces fabricated via spray-deposition and photopolymerization.

Science.gov (United States)

Sparks, Bradley J; Hoff, Ethan F T; Xiong, Li; Goetz, James T; Patton, Derek L

2013-03-13

We report a simple and versatile method for the fabrication of superhydrophobic inorganic-organic thiol-ene coatings via sequential spray-deposition and photopolymerization under ambient conditions. The coatings are obtained by spray-deposition of UV-curable hybrid inorganic-organic thiol-ene resins consisting of pentaerythritol tetra(3-mercaptopropionate) (PETMP), triallyl isocyanurate (TTT), 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane (TMTVSi), and hydrophobic fumed silica nanoparticles. The spray-deposition process and nanoparticle agglomeration/dispersion provide surfaces with hierarchical morphologies exhibiting both micro- and nanoscale roughness. The wetting behavior, dependent on the concentration of TMTVSi and hydrophobic silica nanoparticles, can be varied over a broad range to ultimately provide coatings with high static water contact angles (>150°), low contact angle hysteresis, and low roll off angles (spray-deposition and UV-cure process on a variety of substrate surfaces including glass, paper, stone, and cotton fabric.

Preliminary Engineering Report contaminated groundwater seeps 317/319/ENE area

International Nuclear Information System (INIS)

1996-01-01

When the Resource Conservation and Recovery Act Facility Investigation (RFI) in the 317/319/ENE Area of Argonne National Laboratory-East (ANL-E) was being completed, groundwater was discovered moving to the surface through a series of seeps. The seeps are located approximately 600 ft south of the ANL fence line in Waterfall Glen Forest Preserve. Samples of this water were collected and analyzed for selected parameters. Two of five seeps sampled were found to contain detectable levels of organic contaminants. Three chemical species were identified: chloroform (14-25 μg/L), carbon tetrachloride (56-340 μg/L), and tetrachloroethylene (3-6 μg/L). The other seeps did not contain detectable levels of volatile organic compounds (VOCs). The water issuing from these two contaminated seeps flows into a narrow ravine, where it is visible as a trickle of water flowing through sand and gravel deposits on the floor of the ravine. Approximately 100-ft downstream of the seep area, the contaminated water is no longer visible, having drained back into the soil in the bed of the ravine. Figure 1 shows the location of the 317/319/ENE Area in relation to the ANL-E site and the Waterfall Glen Forest Preserve

Stereoselectivity in ene reactions with 1O2: matrix effects in polymer supports, photo-oxygenation of organic salts and asymmetric synthesis.

Science.gov (United States)

Griesbeck, Axel G; Bartoschek, Anna; Neudörfl, Jörg; Miara, Claus

2006-01-01

The ene reaction of chiral allylic alcohols is applied as a tool for the investigation of intrapolymer effects by means of the stereoselectivity of the singlet-oxygen addition. The diastereo selectivity strongly depends on the structure of the polymer, the substrate loading degree and also on the degree of conversion demonstrating additional supramolecular effects evolving during the reaction. The efficiency and the stability of polymer-bound sensitizers were evaluated by the ene reaction of singlet oxygen with citronellol. The ene reaction with chiral ammonium salts of tiglic acid was conducted under solution phase conditions or in polystyrene beads under chiral contact ion-pair conditions. The products thus obtained precipitate during the photoreaction as ammonium salts. Moderate asymmetric induction was observed for this procedure for the first time.

Synergistic Diazo-OH Insertion/Conia-Ene Cascade Catalysis for the Stereoselective Synthesis of γ-Butyrolactones and Tetrahydrofurans.

Science.gov (United States)

Hunter, Arianne C; Schlitzer, Steven C; Sharma, Indrajeet

2016-11-02

A novel and highly efficient diazo-OH insertion/Conia-ene cascade reaction of readily available homopropargylic acids and alcohols with diazo carbonyl compounds is described. The cascade reaction involves a synergistic Rh/Ag/Au catalyst cocktail and proceeds instantly with a variety of substituted diazo compounds and acids/alcohols to provide functionalized γ-butyrolactones and tetrahydrofurans with complete regio- and stereoselectivity. The unprecedented rate-enhancement, complete stereoselectivity, and the enabling of new Conia-ene cyclizations suggest a concerted [4+1]-cycloaddition reaction pathway under synergistic (Rh/Ag/Au)-catalysis conditions. © 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

One-step fabrication of PEGylated fluorescent nanodiamonds through the thiol-ene click reaction and their potential for biological imaging

Science.gov (United States)

Huang, Hongye; Liu, Meiying; Tuo, Xun; Chen, Junyu; Mao, Liucheng; Wen, Yuanqing; Tian, Jianwen; Zhou, Naigen; Zhang, Xiaoyong; Wei, Yen

2018-05-01

Over the past years, fluorescent carbon nanoparticles have got growing interest for biological imaging. Fluorescent nanodiamonds (FNDs) are novel fluorescent carbon nanoparticles with multitudinous useful properties, including remarkable fluorescence properties, extremely low toxicity and high refractive index. However, facile preparation of FNDs with designable properties and functions from non-fluorescent detonation nanodiamonds (DNDs) has demonstrated to be challengeable. In this work, we reported for the first time that preparation of Polyethylene glycol (PEG) functionalized FNDs through a one-step thiol-ene click reaction using thiol containing PEG (PEG-SH) as the coating agent. Based on the characterization results, we demonstrated that PEG-SH could be efficiently introduced on DNDs to obtain FNDs through the thiol-ene click chemistry. The resultant FND-PEG composites showed high water dispersibility, strong fluorescence and low cytotoxicity. Moreover, FND-PEG composites could be internalized by cells and displayed good cell dyeing performance. All of these features implied that FND-PEG composites are of great potential for biological imaging. Taken together, a facile one-step strategy based on the one-step thiol-ene click reaction has been developed for efficient preparation of FND-PEG composites from non-fluorescent DNDs. The strategy should be also useful for fabrication of many other functional FNDs via using different thiol containing compounds for the universality of thiol-ene click reaction.

Stavovi medicinskih sestara u Hrvatskoj o primarnom oživljavanju prijevremeno rođene novorođenčadi

OpenAIRE

Bilić, Iva; Prpić, Igor; Radić, Jelena; Vukelić, Petar; Petrović, Ana; Juretić, Emilija; Furlan, Ivanka

2008-01-01

CILJ: Cilj istraživanja bilo je ispitati stavove medicinskih sestara u Hrvatskoj o primarnom oživljavanju prijevremeno rođene djece. METODE: Pisanom anketom ispitivana je dob, roditeljstvo, radno iskustvo i mjesto rada te stavovi medicinskih sestara iz Hrvatske o primarnom oživljavanju prijevremeno rođene djece. Anketirano je 174 medicinskih sestara; 49 zaposlenih u rađaonici ili na mjestima rada sa trudnicama (Rađ/Tr), 79 u pedijatrijskim/ neonatološkim jedinicama intenzivnog liječenja (...

Advantages and drawbacks of Thiol-ene based resins for 3D-printing

Science.gov (United States)

Leonards, Holger; Engelhardt, Sascha; Hoffmann, Andreas; Pongratz, Ludwig; Schriever, Sascha; Bläsius, Jana; Wehner, Martin; Gillner, Arnold

2015-03-01

The technology of 3D printing is conquering the world and awakens the interest of many users in the most varying of applications. New formulation approaches for photo-sensitive thiol-ene resins in combination with various printing technologies, like stereolithography (SLA), projection based printing/digital light processing (DLP) or two-photon polymerization (TPP) are presented. Thiol-ene polymerizations are known for its fast and quantitative reaction and to form highly homogeneous polymer networks. As the resins are locally and temporally photo-curable the polymerization type is very promising for 3D-printing. By using suitable wavelengths, photoinitiator-free fabrication is feasible for single- and two photon induced polymerization. In this paper divinyl ethers of polyethylene glycols in combination with star-shaped tetrathiols were used to design a simple test-system for photo-curable thiol-ene resins. In order to control and improve curing depth and lateral resolution in 3D-polymerization processes, either additives in chemical formulation or process parameters can be changed. The achieved curing depth and resolution limits depend on the applied fabrication method. While two-/multiphoton induced lithography offers the possibility of micron- to sub-micron resolution it lacks in built-up speed. Hence single-photon polymerization is a fast alternative with optimization potential in sub-10-micron resolution. Absorber- and initiator free compositions were developed in order to avoid aging, yellowing and toxicity of resulting products. They can be cured with UV-laser radiation below 300 nm. The development at Fraunhofer ILT is focusing on new applications in the field of medical products and implants, technical products with respect to mechanical properties or optical properties of 3D-printed objects. Recent process results with model system (polyethylene glycol divinylether/ Pentaerithrytol tetrakis (3-mercaptopropionat), Raman measurements of polymer conversion

Heterofunctional Glycopolypeptides by Combination of Thiol-Ene Chemistry and NCA Polymerization.

Science.gov (United States)

Krannig, Kai-Steffen; Schlaad, Helmut

2016-01-01

Glycopolypeptides are prepared either by the polymerization of glycosylated amino acid N-carboxyanhydrides (NCAs) or by the post-polymerization functionalization of polypeptides with suitable functional groups. Here we present a method for the in-situ functionalization and (co-) polymerization of allylglycine N-carboxyanhydride in a facile one-pot procedure, combining radical thiol-ene photochemistry and nucleophilic ring-opening polymerization techniques, to yield well-defined heterofunctional glycopolypeptides.

Valme / Aisopos ; tlk. Kaarina Krull

Index Scriptorium Estoniae

Aisopos, 6.saj. e.Kr.

1999-01-01

Sisu : Rebane ja leopard; Rebane ja koomiline mask; Pime; Inimesed ja Zeus; Inimene ja saatür; Vanamees ja surm; Rändur Diogenes; Zeus ja inimesed; Zeus, Prometheus, Athena ja Momos; Herakles ja Plutos; Mees kes kitaara saatel laulis

Continuous Flow Science in an Undergraduate Teaching Laboratory: Photocatalytic Thiol-Ene Reaction Using Visible Light

Science.gov (United States)

Santandrea, Jeffrey; Kairouz, Vanessa; Collins, Shawn K.

2018-01-01

An undergraduate teaching laboratory experiment involving a continuous flow, photocatalytic thiol-ene reaction using visible-light irradiation is described that allows students to explore concepts of green chemistry, photochemistry, photocatalysis, and continuous flow chemistry.

Emplazamiento hacia el ENE del manto de Los Reales (Alpujarrides occidentales: criterios estructurales y de petrofábrica

Directory of Open Access Journals (Sweden)

Tubía, J. M.

1984-08-01

Full Text Available Los Reales nappe rests over Ojén nappe to the North of Sierra Alpujata. The nappe contact zone shows a intense plastic deformation with mylonitic rocks, The deformation decreases progressively going away from the contacto The structural study of footwall and hangingwall roen permits to attribute this deformation to the Los Reales nappe emplacement over that of Ojén. The foliation and stretching lineation distributions show a WSW-ENE shear direction. The mylonite microstructural characteristics and the enstatite crystalline preferred orientations in the basal peridotites give a mear sense in according that, Los Reales nappe is displaced, in their present position, from the WSW towards the ENE.

El manto de Los Reales descansa sobre el manto de Ojén, al norte de Sierra Alpujata. La zona de contacto entre mantos exhibe una intensa deformación plástica con rocas miloníticas; la deformación disminuye progresivamente al alejarse del contacto. El estudio estructural de las rocas infra y suprayacentes al contacto permite atribuir esta deformación al emplazamiento del manto de Los Reales sobre el de Ojén. , Las distribuciones de la foliación y de la lineación, de estiramiento indican una dirección de cizallamiento WSW-ENE. Las características microestructurales de las milonitas y las orientaciones preferentes cristalinas de la enstatita en las peridotitas basales proporcionan un sentido de cizallamiento tal que el manto de Los Reales se ha desplazado, en su posición actual, desde el WSW hacia el ENE.

Efforts toward rapid construction of the cortistatin A carbocyclic core via enyne-ene metathesis

KAUST Repository

Baumgartner, Corinne; Ma, Sandy; Liu, Qi; Stoltz, Brian M.

2010-01-01

Our efforts toward the construction of the carbocylic core of cortistatin A via an enyne-ene metathesis are disclosed. Interestingly, an attempted S N2 inversion of a secondary mesylate in our five-membered D-ring piece gave a product with retention

Preparation and Characterization of Fluorinated Hydrophobic UV-Crosslinkable Thiol-Ene Polyurethane Coatings

OpenAIRE

Wenjing Xia; Nianqing Zhu; Rongjie Hou; Wengui Zhong; Mingqing Chen

2017-01-01

The polyurethane prepolymer terminated with a double bond was synthesized using isophorone diisocyanate (IPDI), hydroxyl terminated polybutadiene (HTPB), 1,4-butanediol (BDO), and 2-hydroxyethyl acrylate (HEA). Then, a series of innovative UV-curable polyurethane coatings were prepared by blending ene-terminated polyurethane, fluoroacrylate monomer, and multifunctional thiol crosslinker upon UV exposure. The incorporation of fluoroacrylate monomer and multifunctional thiols into polyurethane ...

High performance thiol-ene thermosets based on fully bio-based poly(limonene carbonate)s

NARCIS (Netherlands)

Li, C.; Johansson, M.; Sablong, R.J.; Koning, C.E.

2017-01-01

High glass transition temperature (Tg) thiol-ene networks (TENs) based on poly(limonene carbonate)s (PLCs), derived from orange oils and of potential degradability are described here. PLCs with moderate molecular weight were prepared by copolymerization of limonene oxide with CO2 and subsequent

Nava tiigi ääres seiklevad Hunt ja Rebane / Liisi Seil ; kommenteerinud Pille Põllumäe

Index Scriptorium Estoniae

Seil, Liisi, 1971-

2009-01-01

17.-19. juulini Lilli külas Nava talus toimuvast 4. Nava lava festivalist. 19. 07 mängib Karksi valla kultuurikeskuse noorteteater "O" lasteetendust "Hundi ja Rebase lend lõunanabale", mille on Nava talu peremehe Jaak Kõdari raamatu "Kriimureinulised lood. 3, Argonaudid" põhjal kirjutanud ja lavastanud Silvia Soro. Kostüümid tegi Thea Ilusmets. 17., 18. ja 19. 07 mängitakse Jaak Kõdari mulgikeelset külanäitemängu "Kõik läheb mööda, kõik tuleb jälle. 1912-1918", lavastaja Silvia Soro

ENED-GEM: A Conceptual Framework Model for Psychological Enjoyment Factors and Learning Mechanisms in Educational Games about the Environment

Science.gov (United States)

Fjællingsdal, Kristoffer S.; Klöckner, Christian A.

2017-01-01

Based on a thorough review of psychological literature, this article seeks to develop a model of game enjoyment and environmental learning (ENvironmental EDucational Game Enjoyment Model, ENED-GEM) and delineate psychological processes that might facilitate learning and inspire behavioral change from educational games about the environment. A critically acclaimed digital educational game about environmental issues (Fate of the World by Red Redemption/Soothsayer Games) was used as a case study. Two hundred forty-nine reviews of the game from the popular gaming and reviewing platform known as Steam were analyzed by means of a thematic content analysis in order to identify key player enjoyment factors believed to be relevant to the process of learning from games, as well as to gain an understanding of positive and negative impressions about the game’s general content. The end results of the thematic analysis were measured up to the suggested ENED-GEM framework. Initial results generally support the main elements of the ENED-GEM, and future research into the importance of these individual core factors is outlined. PMID:28701988

ENED-GEM: A Conceptual Framework Model for Psychological Enjoyment Factors and Learning Mechanisms in Educational Games about the Environment

Directory of Open Access Journals (Sweden)

Kristoffer S. Fjællingsdal

2017-06-01

Full Text Available Based on a thorough review of psychological literature, this article seeks to develop a model of game enjoyment and environmental learning (ENvironmental EDucational Game Enjoyment Model, ENED-GEM and delineate psychological processes that might facilitate learning and inspire behavioral change from educational games about the environment. A critically acclaimed digital educational game about environmental issues (Fate of the World by Red Redemption/Soothsayer Games was used as a case study. Two hundred forty-nine reviews of the game from the popular gaming and reviewing platform known as Steam were analyzed by means of a thematic content analysis in order to identify key player enjoyment factors believed to be relevant to the process of learning from games, as well as to gain an understanding of positive and negative impressions about the game’s general content. The end results of the thematic analysis were measured up to the suggested ENED-GEM framework. Initial results generally support the main elements of the ENED-GEM, and future research into the importance of these individual core factors is outlined.

ENED-GEM: A Conceptual Framework Model for Psychological Enjoyment Factors and Learning Mechanisms in Educational Games about the Environment.

Science.gov (United States)

Fjællingsdal, Kristoffer S; Klöckner, Christian A

2017-01-01

Based on a thorough review of psychological literature, this article seeks to develop a model of game enjoyment and environmental learning (ENvironmental EDucational Game Enjoyment Model, ENED-GEM) and delineate psychological processes that might facilitate learning and inspire behavioral change from educational games about the environment. A critically acclaimed digital educational game about environmental issues (Fate of the World by Red Redemption/Soothsayer Games) was used as a case study. Two hundred forty-nine reviews of the game from the popular gaming and reviewing platform known as Steam were analyzed by means of a thematic content analysis in order to identify key player enjoyment factors believed to be relevant to the process of learning from games, as well as to gain an understanding of positive and negative impressions about the game's general content. The end results of the thematic analysis were measured up to the suggested ENED-GEM framework. Initial results generally support the main elements of the ENED-GEM, and future research into the importance of these individual core factors is outlined.

Efforts toward rapid construction of the cortistatin A carbocyclic core via enyne-ene metathesis

KAUST Repository

Baumgartner, Corinne

2010-01-01

Our efforts toward the construction of the carbocylic core of cortistatin A via an enyne-ene metathesis are disclosed. Interestingly, an attempted S N2 inversion of a secondary mesylate in our five-membered D-ring piece gave a product with retention of stereochemistry. © 2010 The Royal Society of Chemistry.

Amino acid-incorporated polymer network by thiol-ene polymerization

Directory of Open Access Journals (Sweden)

R. Yokose

2015-08-01

Full Text Available Triallyl L-alanine (A3A and triallyl L-phenylalanine (A3F were synthesized by reactions of L-alanine and L-phenylalanine with allyl bromide in the presence of sodium hydroxide, respectively. Thiol-ene thermal polymerization of A3A or A3F with pentaerythritol-based primary tetrathiol (pS4P or pentaerythritol-based secondary tetrathiol (S4P at allyl/SH 1/1 in the presence of 2,2'-azobis(isobutyronitrile produced an amino acid-incorporated polymer network (A3ApS4P, A3A-S4P or A3F-S4P. Although the thermally cured resins were homogeneous and flat films, the corresponding thiol-ene photopolymerization did not give a successful result. Degree of swelling for each thermally cured film in N,Ndimethylformamide was much higher than that in water. The glass transition and 5% weight loss temperatures (Tg and T5 of A3F-pS4P and A3F-S4P were higher than those of A3A-pS4P and A3A-S4P, respectively. Also, A3F-pS4P and A3F-S4P exhibited much higher tensile strengths and moduli than A3A-pS4P and A3A-S4P did, respectively. Consequently, A3FpS4P displayed the highest Tg (38.7°C, T5 (282.0°C, tensile strength (9.5 MPa and modulus (406 MPa among all the thermally cured resins.

Ene-Liis Semper : Kohalolu piiritsoonis = Presence in the border zone / Anu Allas

Index Scriptorium Estoniae

Allas, Anu, 1977-

2007-01-01

Teatri- ja videokunstnik Ene-Liis Semperi peamiselt 1990-ndate aastate videotest, mis on valdavalt rõhutatult lavastuslikud, paisutatult sümbolistlikud või kus on esitatud piirsituatsioone, ahistust ning selle teadlikku eksponeerimist väljakutsena publikule. Iseennast paljastades, alandades ja ohtu seades jääb kunstnik enamasti jahedalt distantseerituks, publikule jääb aga arusaamatuks, kas tegemist on ohvri, kangelanna või osava mänguriga

1-Methoxy-3-o-tolylbicyclo[2.2.2]oct-5-ene-2,2-dicarbonitrile

Directory of Open Access Journals (Sweden)

Orhan Büyükgüngör

2009-09-01

Full Text Available In the title compound, C18H18N2O, the cyclohexene and cyclohexane rings of the bicyclo[2.2.2]oct-5-ene unit adopt distorted boat conformations. In the crystal, molecules exist as C—H...N hydrogen-bonded centrosymmetric R22(14 dimers, which are further linked by C—H...π interactions.

Thiol-Ene Photo-Click Collagen-PEG Hydrogels: Impact of Water-Soluble Photoinitiators on Cell Viability, Gelation Kinetics and Rheological Properties

Directory of Open Access Journals (Sweden)

Róisín Holmes

2017-06-01

Full Text Available Thiol-ene photo-click hydrogels were prepared via step-growth polymerisation using thiol-functionalised type-I collagen and 8-arm poly(ethylene glycol norbornene-terminated (PEG-NB, as a potential injectable regenerative device. Type-I collagen was thiol-functionalised by a ring opening reaction with 2-iminothiolane (2IT, whereby up to 80 Abs.% functionalisation and 90 RPN% triple helical preservation were recorded via 2,4,6-Trinitrobenzenesulfonic acid (TNBS colorimetric assay and circular dichroism (CD. Type, i.e., either 2-Hydroxy-1-[4-(2-hydroxyethoxy phenyl]-2-methyl-1-propanone (I2959 or lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP, and concentration of photoinitiator were varied to ensure minimal photoinitiator-induced cytotoxicity and to enable thiol-ene network formation of collagen-PEG mixtures. The viability of G292 cells following 24 h culture in photoinitiator-supplemented media was largely affected by the photoinitiator concentration, with I2959-supplemented media observed to induce higher toxic response (0.1 → 0.5% (w/v I2959, cell survival: 62 → 2 Abs.% compared to LAP-supplemented media (cell survival: 86 → 8 Abs.%. In line with the in vitro study, selected photoinitiator concentrations were used to prepare thiol-ene photo-click hydrogels. Gelation kinetics proved to be largely affected by the specific photoinitiator, with LAP-containing thiol-ene mixtures leading to significantly reduced complete gelation time (τ: 187 s with respect to I2959-containing mixtures (τ: 1683 s. Other than the specific photoinitiator, the photoinitiator concentration was key to adjusting the hydrogel storage modulus (G’, whereby 15-fold G’ increase (232 → 3360 Pa was observed in samples prepared with 0.5% (w/v compared to 0.1% (w/v LAP. Further thiol-ene formulations with 0.5% (w/v LAP and varied content of PEG-NB were tested to prepare photo-click hydrogels with porous architecture, as well as tunable storage modulus (G�

Koolirõõmuta kool on lapsele kui sunnitöö / Ene-Silvia Sarv ; intervjueerinud Karin Klaus

Index Scriptorium Estoniae

Sarv, Ene-Silvia, 1945-

2013-01-01

Intervjuu Pärnus hariduskonverentsil "Õnnelik õpilane, õnnelik õpetaja" esinenud Tallinna ülikooli lektori Ene-Silvia Sarvega, kes rääkis oma ettekandes, milline paistab tänapäeva kool õpilaste silme läbi ja mis mõjutab koolikliimat kõige enam

Rapid and simple preparation of thiol–ene emulsion-templated monoliths and their application as enzymatic microreactors

Czech Academy of Sciences Publication Activity Database

Lafleur, J. P.; Senkbeil, S.; Novotný, Jakub; Nys, G.; Bøgelund, N.; Rand, K. D.; Foret, František; Kutter, J. P.

2015-01-01

Roč. 15, č. 10 (2015), s. 2162-2172 ISSN 1473-0197 R&D Projects: GA ČR(CZ) GBP206/12/G014 Institutional support: RVO:68081715 Keywords : thiol-enes * mictoreactor * monolith * fabrication * proteins Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 5.586, year: 2015

Kas erivajadustega lapsed saavad õigel ajal abi? / Ene Mägi, Urve Raudsepp-Alt, Ale Sprenk, Peeter Aas

Index Scriptorium Estoniae

2009-01-01

Küsimusele vastavad: Tallinna Ülikooli Kasvatusteaduste Instituudi eri- ja sotsiaalpedagoogika osakonna juhataja Ene Mägi, Tallinna Haridusameti üldhariduse osakonna peaspetsialist Urve Raudsepp-Alt, Krabi põhikooli direktor Ale Sprenk, Põlva Maavalitsuse haridus-, kultuuri- ja sotsiaalosakonna juhataja Peeter Aas

Poly(ethylene glycol)-based thiol-ene hydrogel coatings: curing chemistry, aqueous stability, and potential marine antifouling applications

NARCIS (Netherlands)

Lundberg, P.; Bruin, A.; Klijnstra, J.W.; Nyström, A.M.; Johansson, M.; Malkoch, M.; Hult, A.

2010-01-01

Photocured thiol-ene hydrogel coatings based on poly(ethylene glycol) (PEG) were investigated for marine antifouling purposes. By varying the PEG length, vinylic end-group, and thiol cross-linker, a library of hydrogel coatings with different structural composition was efficiently accomplished, with

Limitations of the Neurological Evolutional Exam (ENE as a motor assessment for first graders Limitações do Exame Neurológico Evolutivo (ENE como um instrumento de avaliação motora para crianças da primeira série

Directory of Open Access Journals (Sweden)

Priscila M. Caçola

2010-10-01

Full Text Available BACKGROUND: Many clinicians and researchers in Brazil consider the Neurological Developmental Exam (NDE, a valid and reliable assessment for Brazilian school-aged children. However, since its inception, several tests have emerged that, according to some researchers, provide more in-depth evaluation of motor ability and go beyond the detection of general motor status (soft neurological signs. OBJECTIVES: To highlight the limitations of the NDE as a motor skill assessment for first graders. METHODS: Thirty-five children were compared on seven selected items of the NDE, seven of the Bruininks-Oseretsky Test (BOT, and seven of the Visual-Motor Integration test (VMI. Participants received a "pass" or "fail" score for each item, as prescribed by the respective test manual. RESULTS: Chi-square and ANOVA results indicated that the vast majority of children (74% passed the NDE items, whereas values for the other tests were 29% (BOT and 20% (VMI. Analysis of specific categories (e.g. visual, fine, and gross motor coordination revealed a similar outcome. CONCLUSIONS: Our data suggest that while the NDE may be a valid and reliable test for the detection of general motor status, its use as a diagnostic/remedial tool for identifying motor ability is questionable. One of our recommendations is the consideration of a revised NDE in light of the current needs of clinicians and researchers.CONTEXTUALIZAÇÃO: Muitos clínicos e pesquisadores brasileiros consideram o Exame Neurológico Evolutivo (ENE, um instrumento válido e confiável para crianças brasileiras em idade escolar. Entretanto, desde a sua criação, surgiram outros testes para uma avaliação mais profunda de habilidade motora, os quais vão além de detectar status motor geral em forma de sinais neurológicos leves. OBJETIVOS: Demonstrar os pontos fracos do ENE como teste de avaliação de habilidade motora para crianças de primeira série. MÉTODOS: Trinta e cinco crianças realizaram 7 itens

A Convergent Enantioselective Total Synthesis of (-)-Perhydrohistrionicotoxin with an Intramolecular Imino Ene-type Reaction as a Key Step

DEFF Research Database (Denmark)

Tanner, David Ackland; Hagberg, Lars

1998-01-01

A convergent enantioselective total synthesis of the neurotoxic spirocyclic alkaloid (-)-perhydrohistrionicotoxin (2) is described. A Lewis acid-mediated intramolecular imine ene-type reaction was used for the key spirocyclisation step (14 to 3, with 3 being obtained as a single diastereoisomer...

Draama 2007. Töörahu / Ene Paaver

Index Scriptorium Estoniae

Paaver, Ene, 1963-

2008-01-01

Ülevaade 2007. aasta eesti draamast. Pikemalt käsitletakse järgmisi autoreid ja nende näidendeid: Mart Kivastik "Tõnu võitlused", Mart Kivastik "Eesti asi", Mart Kivastik "Sõdur", Mart Kivastik "Kuninga viimane lahing ja ülikooli algus", Mart Kivastik, "Nokia 3310", Andrus Kivirähk "Voldemar", Andrus Kivirähk "Uljas neitsi", Hendrik Toompere "Kommunisti surm", Andres Ehin "Saatuslik kihlvedu ehk Volquin Varbola all", Jan Rahman "Jõujaam", Jaak Kõdar "Muinassaar", Karl Berg "Teekond valguse riiki", Angela Randmets "Lembelood vanas linnas", Toomas Kall "Tähtede sadu", Lauri Vahtre "Muna EÜE", Urmas Espenberg "Kestvad kiiduavaldused", Kalju Saaber "Koduvõõrad", Indrek Hirv "Pauluse kiriku kellad", Katrin Saukas "Võlg", Heidi Sarapuu "Austatud Riigikogu liikmed!", Heidi Sarapuu "Helisev viis", Heidi Sarapuu "Ankur hiivata", Jakob Karu "Vanaema juures", Jim Ashilevi "Nagu poisid vihma käes", Jim Ashilevi "Portselansuits", Eva Koff "Mirr", Jaak Prints "Karaoke", Kati Murutar "Mina, naine!", Ott Aardam "Börs ja Börsitar", Andrus Kivirähk, Jan Rahman, Contra "Kõrts", Mart Kase "Perekond", Villu Tamme "Haned võlgu"; Tiit Ojasoo ja Ene-Liis Semperi "GEP ehk Gorjatshije estonskije parni"

Investigation of curing rates of bio-based thiol-ene films from diallyl 2,5-furandicaboxylate

DEFF Research Database (Denmark)

Larsen, Daniel Bo; Sønderbæk-Jørgensen, Rene; Duus, Jens Ø.

2018-01-01

The bio-based monomer, 2,5-furandicarboxylic acid, has been adapted to classic thiol-ene chemistry by derivatization of the acid with allyl alcohol. This new monomer has allowed for the synthesis of new thermoset systems, capable of forming green, sustainable materials through UV-crosslinking. In......The bio-based monomer, 2,5-furandicarboxylic acid, has been adapted to classic thiol-ene chemistry by derivatization of the acid with allyl alcohol. This new monomer has allowed for the synthesis of new thermoset systems, capable of forming green, sustainable materials through UV......-crosslinking. In this study, the synthesis of the new monomer along with thorough kinetic studies of the new thermoset systems are presented. In order to determine kinetic values for the systems, all reactions have been followed by real-time FT-IR. Initially, a study of three different photoinitiators is performed...... on a classic TEMPIC-TATATO system, in order to determine the superior initiator for the new systems. The new monomer is crosslinked with five different thiol compounds in both stoichiometric and off-stoichiometric ratios, yielding an array of bio-based thermosets. The properties of these systems are determined...

Assessment of the role of in situ generated (E)-2,4-diene-valproic acid in the toxicity of valproic acid and (E)-2-ene-valproic acid in sandwich-cultured rat hepatocytes

Energy Technology Data Exchange (ETDEWEB)

Surendradoss, Jayakumar; Chang, Thomas K.H.; Abbott, Frank S., E-mail: frank.abbott@ubc.ca

2012-11-01

Valproic acid (VPA) undergoes cytochrome P450-mediated desaturation to form 4-ene-VPA, which subsequently yields (E)-2,4-diene-VPA by β-oxidation. Another biotransformation pathway involves β-oxidation of VPA to form (E)-2-ene-VPA, which also generates (E)-2,4-diene-VPA by cytochrome P450-mediated desaturation. Although the synthetic form of (E)-2,4-diene-VPA is more hepatotoxic than VPA as shown in various experimental models, there is no conclusive evidence to implicate the in situ generated (E)-2,4-diene-VPA in VPA hepatotoxicity. The present study investigated the effects of modulating the in situ formation of (E)-2,4-diene-VPA on markers of oxidative stress (formation of 2′,7′-dichlorofluorescein; DCF), steatosis (accumulation of BODIPY 558/568 C{sub 12}), necrosis (release of lactate dehydrogenase; LDH), and on cellular total glutathione (GSH) levels in sandwich-cultured rat hepatocytes treated with VPA or (E)-2-ene-VPA. Treatment with either of these chemicals alone increased each of the toxicity endpoints. In VPA-treated hepatocytes, (E)-2,4-diene-VPA was detected only at trace levels, even after phenobarbital (PB) pretreatment and there was no effect on the toxicity of VPA. Furthermore, pretreatment with a cytochrome P450 enzyme inhibitor, 1-aminobenzotriazole (1-ABT), did not influence the extent of VPA toxicity in both PB-pretreated and vehicle-pretreated hepatocytes. However, in (E)-2-ene-VPA-treated hepatocytes, PB pretreatment greatly enhanced the levels of (E)-2,4-diene-VPA and this was accompanied by a further enhancement of the effects of (E)-2-ene-VPA on DCF formation, BODIPY accumulation, LDH release, and GSH depletion. Pretreatment with 1-ABT reduced the concentrations of (E)-2,4-diene-VPA and the extent of (E)-2-ene-VPA toxicity; however, this occurred in PB-pretreated hepatocytes, but not in control hepatocytes. In conclusion, in situ generated (E)-2,4-diene-VPA is not responsible for the hepatocyte toxicity of VPA, whereas it

Ene-Liis Semper: selle aasta puhkepäevad võib ühe käe sõrmedel kokku lugeda

Index Scriptorium Estoniae

Semper, Ene-Liis, 1969-

2011-01-01

Tallinna kultuuripealinna projekti panustanud Ene-Liis Semper võtab 2011. aasta sündmused kokku ja selgitab, kuidas jõudsid publiku ette suurlavastused "The Rise and Fall of Estonia", "Three Kingdoms", Põhuteater ning isikunäitus Kumus

Hydrophobic thiol-ene surfaces fabricated via plasma activation and photo polymerization

Science.gov (United States)

Champathet, P.; Ervithayasuporn, V.; Osotchan, T.; Dangtip, S.

2017-09-01

Alumina, such as glazed alumina for electrical insulator, operated in an open field subjects to a very harsh condition; resulting in lifetime shortening. Coating hydrophobic layer on alumina surface can help prolonging its lifetime. In this study, 25 ×25 mm alumina sheets were used as substrates. The hydrophobic composite polymers were prepared from (3-mercaptopropyl)trimethoxysilane(MPTMS), 2,4,6,8-tetramethyl-2,4,6,8tetravinylcyclotetra siloxane(TMTVSi), pentaerythritoltetra(3-mercaptopropionate)(PETMP), 2,2-dimethoxy-2-phe nylaceto phenone(photoinitiator) and heptadecafluorodecylmethacrylate(HEFDMA) via the thiol-ene reaction. The alumina sheets were first activated by dielectric-barrier discharge plasma to improve its adhesion. All the polymers were found to optimize at the ratio of (MPTMS:TMTVSi:PETMP:HDFDMA) to 4:2:1:2 for coating on the alumina substrate. To enhance polymerization, 2,2-dimethoxy-2-phenylaceto phenome was also used as a photoinitiator A proper mixing sequence in the thiol-ene reaction results in film with excellent surface retention after prolong soaking in solvent such as acetone. FTIR shows that S-H and C=C functional groups have significantly changed after photopolymerization and thermally cured. The static contact angle increase from mere 53.0°±1.5° of the uncoated substrate to 120.0°±1.2° after coating. SEM shows the film with clear appearance of a few-micron thick. Under AFM, the coated surface roughness was about 9.3 nm with evenly distributed spikes of a few nanometer in height. The cross-cut test also confirmed the film was very smooth and none of the square of the films detached.

Mida teie oma tervise heaks teete? / Ly Jagor, Ülle Mihhailova, Ene Pill, Katrin Käbin...[jt.

Index Scriptorium Estoniae

2008-01-01

Küsimusele vastavad Pärnu Õppenõustamiskeskuse psühholoog Ly Jagor, Maasika lasteaia juhataja asetäitja Ülle Mihhailova, Tallinna Perekeskuse ja Tähetorni lastekeskuse psühholoog Ene Pill, Tallinna Nõmme Noortemaja väikelaste ringijuht Katrin Käbin, Tääksi Põhikooli õpetaja Silva Kolk

Inorganic-Organic Thiol-ene Coated Mesh for Oil/Water Separation.

Science.gov (United States)

Chen, Qiyi; de Leon, Al; Advincula, Rigoberto C

2015-08-26

A highly efficient mesh for oil/water separation was fabricated by using a superhydrophobic and superoleophilic coating of thiol-ene hybrid, consisting of pentaerythritol tetra(3-mercaptopropionate) (PETMP), 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane (TMTVSi), and hydrophobic fumed silica nanoparticles, via a simple two-step fabrication process. Spray deposition and UV curing photopolymerization were sequentially performed, during which solvent evaporation provides microscale roughness while nanoparticle aggregation forms nanoscale roughness. The hierarchical morphologies were stabilized after UV curing photopolymerization. High contact angle (>150°) and low roll-off angle (<5°) were achieved due to the multiscale roughness structure of the hierarchical morphologies. These coatings also have excellent chemical resistance, as well as temperature and pH stability, after curing.

Thiol-ene thermosets exploiting surface reactivity for layer-by-layer structures and control of penetration depth for selective surface reactivity

DEFF Research Database (Denmark)

Daugaard, Anders Egede; Westh, Andreas; Pereira Rosinha Grundtvig, Ines

Thiol-ene thermosets have been shown to be an efficient platform for preparation of functional polymer surfaces. Especially the effectiveness and versatility of the system has enabled a large variety of network properties to be obtained in a simple and straight-forward way. Due to its selectivity......, various thiols and allyl or other vinyl reactants can be used to obtain either soft and flexible1 or more rigid functional thermosets 2. The methodology permits use of etiher thermal or photochemical conditions both for matrix preparation as well as for surface functionalization. Due to excess reactive...... groups in thµe surface of thiol-ene thermosets, it is possible to prepare surface functional thermosets or to exploit the reactive groups for modular construction and subsequent chemical bonding. Here a different approach preparing monolithic layer-by-layer structures with controlled mechanical...

Ära söö kiles saia ehk kas poliitilist kunsti on võimalik mõista? = Do not eat white bread in plastic, or is it possible to understand political art? / Ene-Liis Semper, Eero Epner

Index Scriptorium Estoniae

Semper, Ene-Liis, 1969-

2006-01-01

Poliitillisest teatrist. NO99 lavastusest "Nafta" (lavastajad, autorid: Tiit Ojasoo, Ene-Liis Semper, kunstnik Ene-Liis Semper). Ettekanne Kaasaegse Kunsti Eesti Keskuse 4. ettekannete päeval "Kunstnike moraalsed valikud kultuurikonfliktides" Tallinna Kunstihoones 27.04.2006. Bibliograafia lk. 112

3-(2-Benzofuranyl)quinuclidin-2-ene derivatives: novel muscarinic antagonists.

Science.gov (United States)

Nordvall, G; Sundquist, S; Johansson, G; Glas, G; Nilvebrant, L; Hacksell, U

1996-08-16

A series of 26 derivatives of the novel muscarinic antagonist 3-(2-benzofuranyl)quinuclidin-2-ene (1) has been synthesized and evaluated for muscarinic and antimuscarinic properties. The affinity of the compounds was determined by competition experiments in homogenates of cerebral cortex, heart, parotid gland, and urinary bladder from guinea pigs using (-)-[3H]-3-quinuclidinyl benzilate as the radioligand, and the antimuscarinic-potency was determined in a functional assay on isolated guinea pig urinary bladder using carbachol as the agonist. The 5-fluorobenzofuranyl derivative was slightly more potent than 1. The 7-bromo-substituted 8 displayed a 14-fold tissue selectivity ratio for muscarinic receptors in the cortex versus the parotid gland. Comparative molecular field analysis and quantitative structure-activity relationship models were developed for this series of substituted benzofuranyl derivatives.

Biocatalysis with thermostable enzymes: structure and properties of a thermophilic 'ene'-reductase related to old yellow enzyme.

Science.gov (United States)

Adalbjörnsson, Björn V; Toogood, Helen S; Fryszkowska, Anna; Pudney, Christopher R; Jowitt, Thomas A; Leys, David; Scrutton, Nigel S

2010-01-25

We report the crystal structure of a thermophilic "ene" reductase (TOYE) isolated from Thermoanaerobacter pseudethanolicus E39. The crystal structure reveals a tetrameric enzyme and an active site that is relatively large compared to most other structurally determined and related Old Yellow Enzymes. The enzyme adopts higher order oligomeric states (octamers and dodecamers) in solution, as revealed by sedimentation velocity and multiangle laser light scattering. Bead modelling indicates that the solution structure is consistent with the basic tetrameric structure observed in crystallographic studies and electron microscopy. TOYE is stable at high temperatures (T(m)>70 degrees C) and shows increased resistance to denaturation in water-miscible organic solvents compared to the mesophilic Old Yellow Enzyme family member, pentaerythritol tetranitrate reductase. TOYE has typical ene-reductase properties of the Old Yellow Enzyme family. There is currently major interest in using Old Yellow Enzyme family members in the preparative biocatalysis of a number of activated alkenes. The increased stability of TOYE in organic solvents is advantageous for biotransformations in which water-miscible organic solvents and biphasic reaction conditions are required to both deliver novel substrates and minimize product racemisation.

Hydrophobic Coatings by Thiol-Ene Click Functionalization of Silsesquioxanes with Tunable Architecture.

Science.gov (United States)

Dirè, Sandra; Bottone, Davide; Callone, Emanuela; Maniglio, Devid; Génois, Isabelle; Ribot, François

2017-08-08

The hydrolysis-condensation of trialkoxysilanes under strictly controlled conditions allows the production of silsesquioxanes (SSQs) with tunable size and architecture ranging from ladder to cage-like structures. These nano-objects can serve as building blocks for the preparation of hybrid organic/inorganic materials with selected properties. The SSQs growth can be tuned by simply controlling the reaction duration in the in situ water production route (ISWP), where the kinetics of the esterification reaction between carboxylic acids and alcohols rules out the extent of organosilane hydrolysis-condensation. Tunable SSQs with thiol functionalities (SH-NBBs) are suitable for further modification by exploiting the simple thiol-ene click reaction, thus allowing for modifying the wettability properties of derived coatings. In this paper, coatings were prepared from SH-NBBs with different architecture onto cotton fabrics and paper, and further functionalized with long alkyl chains by means of initiator-free UV-induced thiol-ene coupling with 1-decene (C10) and 1-tetradecene (C14). The coatings appeared to homogeneously cover the natural fibers and imparted a multi-scale roughness that was not affected by the click functionalization step. The two-step functionalization of cotton and paper warrants a stable highly hydrophobic character to the surface of natural materials that, in perspective, suggests a possible application in filtration devices for oil-water separation. Furthermore, the purification of SH-NBBs from ISWP by-products was possible during the coating process, and this step allowed for the fast, initiator-free, click-coupling of purified NBBs with C10 and C14 in solution with a nearly quantitative yield. Therefore, this approach is an alternative route to get sol-gel-derived, ladder-like, and cage-like SSQs functionalized with long alkyl chains.

Fabrication of antibody-loaded microgels using microfluidics and thiol-ene photoclick chemistry.

Science.gov (United States)

Gregoritza, Manuel; Abstiens, Kathrin; Graf, Moritz; Goepferich, Achim M

2018-06-01

Reducing burst effects, providing controlled release, and safeguarding biologics against degradation are a few of several highly attractive applications for microgels in the field of controlled release. However, the incorporation of proteins into microgels without impairing stability is highly challenging. In this proof of concept study, the combination of microfluidics and thiol-ene photoclick chemistry was evaluated for the fabrication of antibody-loaded microgels with narrow size distribution. Norbornene-modified eight-armed poly(ethylene glycol) with an average molecular mass of 10,000 Da, 20,000 Da, or 40,000 Da were prepared as macromonomers for microgel formation. For functionalization, either hydrolytically cleavable ester or stable amide bonds were used. A microfluidic system was employed to generate precursor solution droplets containing macromonomers, the cross-linker dithiothreitol and the initiator Eosin-Y. Irradiation with visible light was used to trigger thiol-ene reactions which covalently cross-linked the droplets. For all bond-types, molecular masses, and concentrations gelation was very rapid (<20 s) and a plateau for the complex shear modulus was reached after only 5 min. The generated microgels had a rod-like shape and did not show considerable cellular toxicity. Stress conditions during the fabrication process were simulated and it could be shown that fabrication did not impair the activity of the model proteins lysozyme and bevacizumab. It was confirmed that the average hydrogel network mesh size was similar or smaller than the hydrodynamic diameter of bevacizumab which is a crucial factor for restricting diffusion and delaying release. Finally, microgels were loaded with bevacizumab and a sustained release over a period of 30 ± 4 and 47 ± 7 days could be achieved in vitro. Copyright © 2018 Elsevier B.V. All rights reserved.

Katkenud õpingute teise kõrgkooli "kolimine" nõuab visadust / Agne Narusk, Ene Küüner, Heli Mattisen, Kadri Osula

Index Scriptorium Estoniae

Narusk, Agne

2007-01-01

Pooleli jäänud ülikooliõpingute lõpetamisest. Varasemate õpingute ja töökogemuse arvestamise tingimusi õpingute jätkamisel selgitavad Tartu Ülikooli avatud ülikooli tasemeõppe koordinaator Ene Küüner, Tallinna Ülikooli akadeemiline prorektor Heli Mattisen ja Estonian Business Schoolì õppeosakonna juhataja Kadri Osula

A neutral polyacrylate copolymer coating for surface modification of thiol-ene microchannels for improved performance of protein separation by microchip electrophoresis

DEFF Research Database (Denmark)

Mesbah, Kiarach; Mai, T.D.; Jensen, Thomas Glasdam

2016-01-01

We have investigated the behavior of thiol-ene substrates that is a class of promising materials for lab-on-a-chip electrophoresis applications. Two polymeric materials were prepared by copolymerization of N, N-dimethylacrylamide (DMA), (3-(methacryloyl-oxy)propyl)trimethoxysilane (PMA) and 3-tri...

Selective fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene by nucleotides.

Science.gov (United States)

Marquez, Cesar; Pischel, Uwe; Nau, Werner M

2003-10-16

[reaction: see text] The fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) by nucleotides has been studied. The quenching mechanism was analyzed on the basis of deuterium isotope effects, tendencies for exciplex formation, and the quenching efficiency in the presence of a molecular container (cucurbit[7]uril). Exciplex-induced quenching appears to prevail for adenosine, cytidine, and uridine, while hydrogen abstraction becomes competitive for thymidine and guanosine. Compared to other fluorescent probes, DBO responds very selectively to the type of nucleotide.

Estonian mills are going to live again : there are twice as many mills in Estonia as there are manors, but most of them are in ruins / Urmas Vahe

Index Scriptorium Estoniae

Vahe, Urmas

2002-01-01

Veskite ja hüdroelektrijaamade rajamise ajaloost, taastamisest ning kasutamisest tänapäeval. Alternatiivsed elektrijaamad kui keskkonna osa. Tabel: Eesti hüdroelektrijaamad, 2002. Kommenteerinud Inge Roos

Kihnu kultuur pälvis koos laulupeoga tunnustuse / Neeme Korv

Index Scriptorium Estoniae

Korv, Neeme, 1974-

2003-01-01

Kihnu kultuuriruumi ja Balti riikide laulu- ja tantsupidude traditsiooni kandmisest UNESCO maailma vaimse ja suulise pärandi nimekirja, materjal aadressli www.unesco.ee/kihnu.pdf. Kommenteerinud Mark Soosaar

Thiol-ene click chemistry derived cationic cyclodextrin chiral stationary phase and its enhanced separation performance in liquid chromatography.

Science.gov (United States)

Yao, Xiaobin; Tan, Timothy Thatt Yang; Wang, Yong

2014-01-24

This work is the first demonstration of a simple thiol-ene click chemistry to anchor vinyl imidazolium β-CD onto thiol silica to form a novel cationic native cyclodextrin (CD) chiral stationary phase (CSP). The CSP afforded high enantioseparation ability towards dansyl (Dns) amino acids, carboxylic aryl compounds and flavonoids in chiral HPLC. The current CSP demonstrates the highest resolving ability (selectivity >1.1, resolution >1.5) towards Dns amino acids in a mobile phase buffered at pH=6.5, with the resolution of Dns-dl-leucine as high as 6.97. 2,4-dichloride propionic acid (2,4-ClPOPA) was well resolved with the selectivity and resolution of 1.37 and 4.88, respectively. Compared to a previously reported native CD-CSP based on a triazole linkage, the current cationic CD-CSP shows a stronger retention and higher resolution towards acidic chiral compounds, ascribed to the propitious strong electrostatic attraction. Stability evaluation results indicated that thiol-ene reaction can provide a facile and robust approach for the preparation of positively charged CD CSPs. Copyright © 2013 Elsevier B.V. All rights reserved.

Functional characterization and stability improvement of a ‘thermophilic-like’ ene-reductase from Rhodococcus opacus 1CP

Directory of Open Access Journals (Sweden)

Anika eRiedel

2015-10-01

Full Text Available Ene-reductases are widely applied for the asymmetric synthesis of relevant industrial chemicals. A novel ene-reductase OYERo2 was found within a set of 14 putative Old Yellow Enzymes (OYEs obtained by genome mining of the actinobacterium Rhodococcus opacus 1CP. Multiple sequence alignment suggested that the enzyme belongs to the group of ‘thermophilic-like’ OYEs. OYERo2 was produced in Escherichia coli and biochemically characterized. The enzyme is strongly NADPH dependent and uses non-covalently bound FMNH2 for the reduction of activated α,β-unsaturated alkenes. In the active form OYERo2 is a dimer. Optimal catalysis occurs at pH 7.3 and 37 °C. OYERo2 showed highest specific activities (4550 U mg-1 on maleimides, which are efficiently converted to the corresponding succinimides. The OYERo2-mediated reduction of prochiral alkenes afforded the (R-products with excellent optical purity (ee > 99%. OYERo2 is not as thermo-resistant as related OYEs. Introduction of a characteristic intermolecular salt bridge by site-specific mutagenesis raised the half-life of enzyme inactivation at 32 °C from 28 min to 87 min and improved the tolerance towards organic co-solvents. The suitability of OYERo2 for application in industrial biocatalysis is discussed.

Polysiloxane-based luminescent elastomers prepared by thiol-ene "click" chemistry.

Science.gov (United States)

Zuo, Yujing; Lu, Haifeng; Xue, Lei; Wang, Xianming; Wu, Lianfeng; Feng, Shengyu

2014-09-26

Side-chain vinyl poly(dimethylsiloxane) has been modified with mercaptopropionic acid, methyl 3-mercaptopropionate, and mercaptosuccinic acid. Coordinative bonding of Eu(III) to the functionalized polysiloxanes was then carried out and crosslinked silicone elastomers were prepared by thiol-ene curing reactions of these composites. All these europium complexes could be cast to form transparent, uniform, thin elastomers with good flexibility and thermal stability. The networks were characterized by FTIR, NMR, UV/Vis, and luminescence spectroscopy as well as by scanning electron microscopy, thermogravimetric analysis, and X-ray photoelectron spectroscopy. The europium elastomer luminophores exhibited intense red light at 617 nm under UV excitation at room temperature due to the (5)D0 →(7)F2 transition in Eu(III) ions. The newly synthesized luminescent materials offer many advantages, including the desired mechanical flexibility. They cannot be dissolved or fused, and so they have potential for use in optical and electronic applications. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Synthesis of Upconverting Hydrogel Nanocomposites Using Thiol-Ene Click Chemistry: Template for the Formation of Dendrimer-Like Gold Nanoparticle Assemblies.

Science.gov (United States)

Meesaragandla, Brahmaiah; Mahalingam, Venkataramanan

2015-11-16

The synthesis of upconverting hydrogel nanocomposites by base-catalyzed thiol-ene click reaction between 10-undecenoic acid capped Yb(3+)/Er(3+)-doped NaYF4 nanoparticles and pentaerythritol tetrakis(3-mercaptopropionate) (PETMP) as tetrathiol monomer is reported. This synthetic strategy for nanocomposite gels is quite different from works where usually the preformed gels are mixed with the nanoparticles. Developing nanocomposites by surface modification of capping ligands would allow tuning and controlling of the separation of the nanoparticles inside the gel network. The hydrogel nanocomposites prepared by thiol-ene click reaction show strong enhancement in luminescence intensity compared to 10-undecenoic acid-capped Yb(3+)/Er(3+)-doped NaYF4 nanoparticles through the upconversion process (under 980 nm laser excitation). The hydrogel nanocomposites display strong swelling characteristics in water resulting in porous structures. Interestingly, the resulting nanocomposite gels act as templates for the synthesis of dendrimer-like Au nanostructures when HAuCl4 is reduced in the presence of the nanocomposite gels. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Kui oluliseks isikuandmete kaitsmist kooli oludes peate ja millest seda tehes lähtute? / Harri Kõo, Ene Tannberg, Kalle Niinas, Maria Tiro...[jt.

Index Scriptorium Estoniae

2008-01-01

Küsimusele vastavad Tabasalu Ühisgümnaasiumi direktor Harri Kõo, Tartu Miina Härma Gümnaasiumi direktor Ene Tannberg, Jakob Westholmi Gümnaasiumi direktor Kalle Niinas, Jüri Gümnaasiumi direktor Maria Tiro ja Viimsi Keskkooli direktor Leelo Tiisvelt

Natura 2000 sai tuule tiibadesse Raplamaal / Ain Aivela

Index Scriptorium Estoniae

Aivela, Ain

2004-01-01

Natura 2000 idee jõudis Eestisse 2000. aastal, mil pilootprojekti raames ning Taani riigi rahalisel toel alustati Natura-võrgustiku eelvalikualade mahamärkimist Lääne- ja Raplamaal. Kommenteerinud Aleksei Lotman

Kolmesaja aasta tagune kroonika sai raamatuks / Meeli Pärtelpoeg

Index Scriptorium Estoniae

Pärtelpoeg, Meeli, 1965-

2006-01-01

Rmt.: Jõelähtme kirik ja kogudus 18. sajandi esimesel poolel. Pastor Heinrich Christopher Wrede ja tema ametijärglaste kroonikamärkmed / transkribeerinud, tõlkinud ja kommenteerinud Tiina Kala. Tallinn : Muinsuskaitseamet, 2006

Kolmekesi ühest Peipsi-äärsest asjast / Tiit Lepp

Index Scriptorium Estoniae

Lepp, Tiit

2007-01-01

Annika Haasi, Birgit Püve ja Age Petersoni fotonäitus "Prichudie, Revisited" Peipsiääre valla inimestest ja elust-olust kunstikeskuses AmbulARToorium Tartumaaal. Kommenteerinud Annika Haas, Birgit Püve, Age Peterson

Linn nopib arhitektuurikonkursist häid ideid / Anu Saare

Index Scriptorium Estoniae

Saare, Anu, 1964-

2004-01-01

Rahvusvahelise arhitektuurikonkursi Europan 7 võidutöö Pärnu rannapiirkonna planeerimiseks on Rumeenia arhitektilt Oana-Maria Bogdanilt. Parematest töödest näitus Muuseumiaidas. Kommenteerinud Pärnu linnaarhitekt Ülar Saar

Raamat sõja seadustest / Linnart Mäll

Index Scriptorium Estoniae

Mäll, Linnart

2001-01-01

Vana-Hiina sõjateoreetikute Sun Zi ja Sun Bini raamatust: Sun, Zi ; Sun, Bin. Sõja seadused / klassikalisest hiina keelest tõlkinud ja kommenteerinud Märt Läänemets. Tln. : Eesti Keele Sihtasutus, 2001. (Sõjandusvaramu. Klassika)

Maagiliste momentide mütoloogia : intervjuu Peter Cook'iga / Peter Cook ; interv. Vilen Künnapu

Index Scriptorium Estoniae

Cook, Peter

2002-01-01

5. Põhja- ja Baltimaade Arhitektuuritriennaalil esinenud inglise arhitekt P. Cook endast, oma loomingust, rühmitusest Archigram, mis pälvis 2002. a. RIBA (Royal Institute of British Architects) kuldmedali, Tallinnast jm. Kommenteerinud Triin Ojari

(E-2-((4R,5R-5-((Benzyloxymethyl-2,2-dimethyl-1,3-dioxolan-4-ylbut-2-ene-1,4-diol

Directory of Open Access Journals (Sweden)

Carlos R. Carreras

2010-04-01

Full Text Available The synthesis of (E-2-((4R,5R-5-((benzyloxymethyl-2,2-dimethyl-1,3-dioxolan-4-ylbut-2-ene-1,4-diol by a one-step reduction of the appropriate 2-substituted butenolide is reported. Product characterization was carried out by IR, 1H NMR, 13C NMR, MS, elemental analysis and optical rotation.

[Raamat] / Kaja Tiisel

Index Scriptorium Estoniae

Tiisel, Kaja

2007-01-01

Rets. rmt.: Jõelähtme kirik ja kogudus 18. sajandi esimesel poolel. Pastor Heinrich Christopher Wrede ja tema ametijärglaste kroonikamärkmed. Transkribeerinud, tõlkinud ja kommenteerinud Tiina Kala. Tallinn : Muinsuskaitseamet, 2006. 420 lk.

Novel Anti-Biofouling Soft Contact Lens: l-Cysteine Conjugated Amphiphilic Conetworks via RAFT and Thiol-Ene Click Chemistry.

Science.gov (United States)

Zhang, Chengfeng; Liu, Ziyuan; Wang, Haiye; Feng, Xiaofeng; He, Chunju

2017-07-01

A unique l-cysteine conjugated antifouling amphiphilic conetwork (APCN) is synthesized through end-crosslinking of well-defined triblock copolymers poly(allyl methacrylate)-b-poly(ethylene glycol)-b-poly(allyl methacrylate) via a combination of reversible addition-fragmentation chain transfer (RAFT) polymerization and thiol-ene "click" chemistry. The synthesized poly(ethylene glycol) macro-RAFT agent initiates the polymerization of allyl methacrylate in a controlled manner. The vinyl pendant groups of the precursor partially conjugate with l-cysteine and the rest fully crosslink with mercaptopropyl-containing siloxane via thiol-ene click chemistry under UV irradiation into APCNs, which show distinguished properties, that is, excellent biocompatibility, more than 39.6% water content, 101 barrers oxygen permeability, optimized mechanical properties, and more than 93% visible light transmittance. What's more, the resultant APCNs exhibit eminent resistance to protein adsorption, where the bovine serum albumin and lysozyme adsorption are decreased to 12 and 21 µg cm -2 , respectively. The outstanding properties of APCNs depend on the RAFT controlled method, which precisely designs the hydrophilic/hydrophobic segments and eventually greatly improves the crosslinking efficiency and homogeneity. Meantime, the l-cysteine monolayer can effectively reduce the surface hydrophobicity and prevent protein adsorption, which exhibits the viability for antifouling surface over and under ophthalmic devices, suggesting a promising soft contact lens. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Kodud mitme mere ääres / Viivi Variksaar

Index Scriptorium Estoniae

Variksaar, Viivi, 1948-

2001-01-01

Ameerikas Hilton Headis elavatest väliseestlastest Erle ja Elmo H. Sergost, nende korterist Tallinnas Poska tänaval. Seintel olevad pildid on maalinud ja kodu kujundanud Erle Sergo. Kommenteerinud Elmo H. Sergo, Erle Sergo. 8 ill

Joint statement of the President, Speaker of the Riigikogu and Prime Minister of the Republic of Estonia / Toomas Hendrik Ilves, Ene Ergma, Andrus Ansip

Index Scriptorium Estoniae

Ilves, Toomas Hendrik, 1953-

2008-01-01

President Toomas Hendrik Ilvese, Riigikogu spiikri Ene Ergma ja peaminister Andrus Ansipi ühisavaldus Teise maailmasõja lõpu 62. aastapäeva puhul 8. mail 2007, milles kinnitatakse, et hoolimata Teise maailmasõja ajaloolistest tõlgendustest on kõik Eestis elavad inimesed vabad ning jagavad ühist tulevikku

Toetuseta jäämine šokeeris mainekat kultuuriajakirja / Ott Raun, Laine Jänes ; interv. Rebekka Lotman ; komment. Marek Tamm

Index Scriptorium Estoniae

Raun, Ott, 1940-

2009-01-01

Eesti Kultuurkapitalinõukogu otsusel jääb ajalookultuuri ajakiri "Tuna" alates 2009. aastast püsitoetusest ilma. Sellega seotud küsimustele vastavad "Tuna" peatoimetaja Ott Raun ja Eesti Kultuurkapitali nõukogu esimees Laine Jänes, kommenteerinud ajaloolane Marek Tamm

Facile preparation of organic-silica hybrid monolith for capillary hydrophilic liquid chromatography based on "thiol-ene" click chemistry.

Science.gov (United States)

Chen, Ming-Luan; Zhang, Jun; Zhang, Zheng; Yuan, Bi-Feng; Yu, Qiong-Wei; Feng, Yu-Qi

2013-04-05

In this work, a one-step approach to facile preparation of organic-inorganic hybrid monoliths was successfully developed. After vinyl-end organic monomers and azobisisobutyronitrile (AIBN) were mixed with hydrolyzed tetramethoxysilane (TMOS) and 3-mercaptopropyltrimethoxysilane (MPTMS), the homogeneous mixture was introduced into a fused-silica capillary for simultaneous polycondensation and "thiol-ene" click reaction to form the organic-silica hybrid monoliths. By employing this strategy, two types of organic-silica hybrid monoliths with positively charged quaternary ammonium and amide groups were prepared, respectively. The functional groups were successfully introduced onto the monoliths during the sol-gel process with "thiol-ene" click reaction, which was demonstrated by ζ-potential assessment, energy dispersive X-ray spectroscopy (EDX), and Fourier transform infrared (FT-IR) spectroscopy. The porous structure of the prepared monolithic columns was examined by scanning electron microscopy (SEM), nitrogen adsorption-desorption measurement, and mercury intrusion porosimetry. These results indicate the prepared organic-silica hybrid monoliths possess homogeneous column bed, large specific surface area, good mechanical stability, and excellent permeability. The prepared monolithic columns were then applied for anion-exchange/hydrophilic interaction liquid chromatography. Different types of analytes, including benzoic acids, inorganic ions, nucleosides, and nucleotides, were well separated with high column efficiency around 80,000-130,000 plates/m. Taken together, we present a facile and universal strategy to prepare organic-silica hybrid monoliths with a variety of organic monomers using one-step approach. Copyright © 2013 Elsevier B.V. All rights reserved.

Crystal and Molecular Structure Studies of Ethyl 4-(4-Hydroxyphenyl-6-(6-methoxy-2-naphthyl-2-oxocyclohex-3-ene-1-carboxylate and Ethyl 4-(3-Bromophenyl-6-(6-methoxy-2-naphthyl-2-oxocyclohex-3-ene-1-carboxylate

Directory of Open Access Journals (Sweden)

Badiadka Narayana

2012-08-01

Full Text Available The crystal and molecular structures of the title compounds, ethyl 4-(4-hydroxyphenyl-6-(6-methoxy-2-naphthyl-2-oxocyclohex-3-ene-1-carboxylate (I and ethyl 4-(3-bromophenyl-6-(6-methoxy-2-naphthyl-2-oxocyclohex-3-ene-1-carboxylate (II, are reported and confirmed by single crystal X-ray diffraction data. Compound (I, C26H24O5, crystallizes from a methanol solution in the monoclinic C2/c space group with eight molecules in the unit cell. The unit cell parameters are: a = 25.4114(5 Å, b = 8.47440(10 Å, c = 20.6921(4 Å, β = 108.328(2° and V = 4229.92(13 Å3. Disorder is observed throughout the entire molecule with an occupancy ratio 0.690(2:0.310(2. Compound (II, C26H23O4Br, crystallizes from an ethyl acetate solution in the monoclinic P21/c spacegroup with four molecules in the unit cell. The unit cell parameters are a = 17.8991(9 Å, b = 11.4369(6 Å, c = 10.8507(5 Å, β = 92.428(4° and V = 2219.25(19 Å3. Disorder is observed in the cyclohexenone ring and the carboxylate group with an occupancy ratio 0.830(6:0.170(6. Weak O–H...O (I or C–H...O (II intermolecular interactions are observed which influence crystal packing stability. These chalcone derivative types of molecules are important in their ability to act as activated unsaturated systems in conjugated addition reactions of carbanions in the presence of basic catalysts which exhibit a multitude of biological activities.

Synthesis and Transformations of di-endo-3-Aminobicyclo-[2.2.2]oct-5-ene-2-carboxylic Acid Derivatives

Directory of Open Access Journals (Sweden)

Márta Palkó

2011-09-01

Full Text Available all-endo-3-amino-5-hydroxybicyclo[2.2.2]octane-2-carboxylic acid (13 and all-endo-5-amino-6-(hydroxymethylbicyclo[2.2.2]octan-2-ol (10 were prepared via dihydro-1,3-oxazine or g-lactone intermediates by the stereoselective functionalization of an N-protected derivative of endo-3-aminobicyclo[2.2.2]oct-5-ene-2-carboxylic acid (2. Ring closure of b-amino ester 4 resulted in tricyclic pyrimidinones 15 and 16. The structures, stereochemistry and relative configurations of the synthesized compounds were determined by IR and NMR.

Vabariigi presidendi, riigikogu esimehe ja peaministri ühisavaldus 8. mail 2007 / Toomas Hendrik Ilves, Ene Ergma, Andrus Ansip

Index Scriptorium Estoniae

Ilves, Toomas Hendrik, 1953-

2007-01-01

President Toomas Hendrik Ilvese, Riigikogu spiikri Ene Ergma ja peaminister Andrus Ansipi avaldus Teise maailmasõja lõpu 62. aastapäeva puhul. Ilmunud ka: Severnoje Poberežje 9. mai 2007, lk. 2; Eesti Elu 11. mai 2007, lk. 2, pealk.: Riigijuhtide ühisavaldus Teise maailmasõja mälestuspäeval, ingl. k. lk. 11, pealk.: Joint statement May 8, 2007; ingl. k. Vaba Eesti Sõna 10. mai 2007, lk. 12, pealk.: Joint statement of the President, Speaker of the Parliament and Prime Minister of the Republic of Estonia

"Tallinna moodul" pakub linnale ühtset vormi / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2004-01-01

Rahvusvahelise ideekonkursi võitis "Fold", autorid Clayton Welham ja Martin Yong Londonist. II koht tööle "Drunken Style", autorid Samson Adjei, Harry Dobbs Ja Greg Epps Londonist. III koht itaalia disaineritele, ergutuspreemiad Argentiinasse ja New Yorki. Kommenteerinud linnadisainer Aavo Ermel

Iron complexes of tetramine ligands catalyse allylic hydroxyamination via a nitroso–ene mechanism

Directory of Open Access Journals (Sweden)

David Porter

2015-12-01

Full Text Available Iron(II complexes of the tetradentate amines tris(2-pyridylmethylamine (TPA and N,N′-bis(2-pyridylmethyl-N,N′-dimethylethane-1,2-diamine (BPMEN are established catalysts of C–O bond formation, oxidising hydrocarbon substrates via hydroxylation, epoxidation and dihydroxylation pathways. Herein we report the capacity of these catalysts to promote C–N bond formation, via allylic amination of alkenes. The combination of N-Boc-hydroxylamine with either FeTPA (1 mol % or FeBPMEN (10 mol % converts cyclohexene to the allylic hydroxylamine (tert-butyl cyclohex-2-en-1-yl(hydroxycarbamate in moderate yields. Spectroscopic studies and trapping experiments suggest the reaction proceeds via a nitroso–ene mechanism, with involvement of a free N-Boc-nitroso intermediate. Asymmetric induction is not observed using the chiral tetramine ligand (+-(2R,2′R-1,1′-bis(2-pyridylmethyl-2,2′-bipyrrolidine ((R,R′-PDP.

Söötmisega disainitud piim tagab tervisliku toidukraami / Ene Tammsaar ; intervjueerinud Ain Alvela ; kommenteerinud Üllas Jaaska

Index Scriptorium Estoniae

Tammsaar, Ene, 1952-

2014-01-01

Et farmidest tööstusse minevast toorpiimast saaks toota maitsvaid ja tervislikke tooteid, peab toorpiim olema kõrgeima võimaliku kvaliteediga. Selle tagamiseks on piimatööstused koostöös teadlastega ette võtnud piima koostise disainimise

Development of a thiol-ene based screening platform for enzyme immobilization demonstrated using horseradish peroxidase

DEFF Research Database (Denmark)

Hoffmann, Christian; Pinelo, Manuel; Woodley, John

2017-01-01

Efficient immobilization of enzymes on support surfaces requires an exact match between the surface chemistry and the specific enzyme. A successful match would normally be identified through time consuming screening of conventional resins in multiple experiments testing individual immobilization...... strategies. In this study we present a versatile strategy that largely expands the number of possible surface functionalities for enzyme immobilization in a single, generic platform. The combination of many individual surface chemistries and thus immobilization methods in one modular system permits faster...... functionalization by thiol-ene chemistry (TEC) resulted in the formation of a functional monolayer in each well, whereas, polymer surface grafts were introduced through surface chain transfer free radical polymerization (SCT-FRP). Enzyme immobilization on the modified surfaces was evaluated by using a rhodamine...

Facile synthesis of linear-dendritic cholesteryl-poly(epsilon-caprolactone)-b-(L-lysine)(G2) by thiol-ene and azide-alkyne "click" reactions

DEFF Research Database (Denmark)

Javakhishvili, Irakli; Binder, W.H.; Tanner, S.

2010-01-01

The construction of a linear-dendritic block copolymer consisting of terminal cholesteryl moiety, poly(epsilon-caprolactone), and a second generation L-lysine dendron has been accomplished by the combination of copper(I) catalyzed azide-alkyne and UV-triggered thiol-ene "click" reactions. Ring-op...... and thiocholesterol. Near to quantitative functionalization of the intermediate and final products has been attained as confirmed by NMR spectroscopy and MALDI-TOF spectrometry....

Ruumieksperiment nimega Arhitektuurikatel = A spatial experiment called Arhitektuurikatel (Architecture Hub) / Artur Ümar, Tõnu Laigu

Index Scriptorium Estoniae

Ümar, Artur

2014-01-01

Arhitektuurikatel Tallinnas Põhja puiesteel. Arhitektuur: Tõnu Laigu, Koit Ojaliiv (QP Arhitektid), võistlusel osalesid ka Helen Rebane ja Triinu Silla. Sisearhitektuur: Andres Labi, Janno Roos (Ruumilabor). Valmimisaasta: 2013

Photolithographic fabrication of solid–liquid core waveguides by thiol-ene chemistry

International Nuclear Information System (INIS)

Sagar, Kaushal; Gopalakrishnan, Nimi; Christiansen, Mads Brøkner; Kristensen, Anders; Ndoni, Sokol

2011-01-01

In this work we demonstrate an efficient and cleanroom compatible method for the fabrication of solid–liquid core waveguides based on nanoporous polymers. We have used thiol-ene photo-grafting to tune and pattern the hydrophilicity of an originally hydrophobic nanoporous 1, 2-polybutadiene. The generated refractive index contrast between the patterned water-filled volume and the surrounding empty hydrophobic porous polymer allows for light confinement within the water-filled volume—the solid–liquid core. The presented fabrication process is simple and fast. It allows a high degree of flexibility on the type and grade of surface chemistry imparted to the large nanoporous area depending upon the application. The fabrication does not need demanding chemical reaction conditions. Thus, it can be readily used on a standard silicon lithography bench. The propagation loss values reported in this work are comparable with literature values for state-of-the-art liquid-core waveguide devices. The demonstrated waveguide function added to the nanoporous polymer with a very high internal surface area makes the system interesting for many applications in different areas, such as diagnostics and bio-chemical sensing

Haapsalu - Põhjamaade Veneetsia / Viivi Variksaar, Lea Arme

Index Scriptorium Estoniae

Variksaar, Viivi, 1948-

2001-01-01

ARS Interjöörprojekti kujundatud hotellist 'Kongo', hotelli restoranist. Reet Siimeri algatusel puuetega ja töötute inimeste toetamiseks loodud 'Värkstoast', kus õpetatakse käsitööd ja müüakse käsitööesemeid. Kommenteerinud Liina Aavik

Muusikale meeldib olla kõikjal / Louis Andriessen ; interv. Harry Liivrand

Index Scriptorium Estoniae

Andriessen, Louis

2000-01-01

Hollandi heliloojast Louis Andriessenist ja tema loomingust. 19. ja 20. sajandi ooperi erinevusest. Ka 1999. a. Amsterdamis esietendunud Louis Andriesseni ja Peter Greenaway ooperist "Writing to Vermeer", mis on pühendatud Jan Vermeer van Delfti ühele elulõigule 1672. a. Kommenteerinud Harry Liivrand, Olari Elts

Vananemise vastu otsitakse abi noorte verest

Index Scriptorium Estoniae

2016-01-01

Füüsik Jesse Karmazin koos endise vaktsiiniuurija Craig Wrightiga panid aluse uuringule (katses osaleks 600 vähemalt 35-aastast inimest, kellele kantakse üle kuni 25-aastaste verest pärit plasma), et uurida vereplasma kui võimaliku noorendava eliksiiri toimet. Kommenteerinud Toivo Maimets

Cinamon kui uus nähtus kinomaastikul / Dagmar Reinolt

Index Scriptorium Estoniae

Reinolt, Dagmar

2009-01-01

Cinamoni kinoketi perspektiividest Eestis. Cinamoni nõukogu esimees Peeter Rebane, Tallinnfilmi juht Margit Vremmert ja kinoketi Forum Cinemas levijuht Lauri Kaare esitavad oma vaateid kinode ja filmilevi kohta Eestis

Siidii / Kreete Reval

Index Scriptorium Estoniae

Reval, Kreete

2003-01-01

Heliplaatidest: Velvet Legion "Velvet Legion", Lou Reed "The Raven", Forgotten Sunrise "Please Disconnect Me", Ry Cooder & Manuel Galban "Mambo Sinuendo", Robert Jürjendal & Henn Rebane "Eesti Asi", Melanie C "Reason"

Thermal decomposition of lanthanides (III) and yttrium (III) solid complexes from ethyl ene diamine tetraacetic acid

International Nuclear Information System (INIS)

Mercadante, A.

1991-01-01

Solid state compounds of lanthanides (III) and yttrium derived from ethyl ene diamine tetraacetic acid were prepared from respective basic carbonates, that were neutralized with EDTA stoichiometry quantities. Complexometry with EDTA, thermogravimetry (TG), differential thermal analysis (DTA) and X-ray diffraction have been used in the study of these compounds. The results of complexometry with EDTA as well as TG and DTA curves bed to the stoichiometry of these compounds the following general formula is obeyed: H[Ln(EDTA]. n H 2 O. X-ray powder patterns of these compounds permitted to establish two isomorphous series. The DTA ant TG curves allowed us to study the dehydration process, the thermal stability and thermal decomposition of these compounds. (C.G.C.)

August toob Vainupeale kontserte

Index Scriptorium Estoniae

2006-01-01

Kontsertidest Vainupeal: Kunda suvekooli noored saksofonistid 10. aug., Jaan Arder ja Henn Rebane 15. aug., kunstinäituse "Blended X" sulgemiskontsert 19. aug., Silvi Vrait ja Jaak Jürisson 26. augustil

Lavater ja Goethe / Linnar Priimägi

Index Scriptorium Estoniae

Priimägi, Linnar, 1954-

2016-01-01

Arvustus: Lavateri näoraamat : valgustusajastu pilk inimesele ja kunstile : toetudes Johann Caspar Lavateri menuteosele "Füsiognoomilisi fragmente inimesetundmise ja ligimesearmastuse edendamiseks" (1775-1778) / koostanud, kommenteerinud ja toimetanud Anu Allikvee ja Tiina-Mall Kreem ; fragmentide tõlge: Katrin Kaugver. Tallinn : Eesti Kunstimuuseum, Mikkeli Muuseum ; Tallinna Ülikool, Akadeemiline Raamatukogu. 2015

Modifying surface resistivity and liquid moisture management property of keratin fibers through thiol-ene click reactions.

Science.gov (United States)

Yu, Dan; Cai, Jackie Y; Church, Jeffrey S; Wang, Lijing

2014-01-22

This paper reports on a new method for improving the antistatic and liquid moisture management properties of keratinous materials. The method involves the generation of thiols by controlled reduction of cystine disulfide bonds in keratin with tris(2-carboxyethyl) phosphine hydrochloride and subsequent grafting of hydrophilic groups onto the reduced keratin by reaction with an acrylate sulfonate or acrylamide sulfonate through thiol-ene click chemistry. The modified substrates were characterized with Raman spectroscopy and scanning electron microscopy and evaluated for their performance changes in liquid moisture management, surface resistivity, and wet burst strength. The results have revealed that the thiol-acrylate reaction is more efficient than the thiol-acrylamide reaction, and the keratinous substrate modified with an acrylate sulfonate salt exhibits significantly improved antistatic and liquid moisture management properties.

Globaalarhitekti uus manifest / Karin Hallas-Murula

Index Scriptorium Estoniae

Hallas-Murula, Karin, 1957-

2004-01-01

Hollandi arhitekt Rem Koolhaas'ist, kelle näitus "Content" Rotterdami Kunstihallis ning näitus "Start" Rotterdami Hollandi Arhitektuuriinstituudis on avatud 31. maini. Näituse "Content" kataloogist. 2000. a. sai R. Koolhaas Pritzkeri preemia, 2003. a. Praemium Imperiale, 2004. a. veebruaris RIBA kuldmedali. Kommenteerinud Andres Alver, Hanno Grossschmidt ja Inga Raukas

Loodame luua pingevaba ja konstruktiivse õhkkonna / Jevgeni Ossinovski ; intervjueerinud Raivo Juurak

Index Scriptorium Estoniae

Ossinovski, Jevgeni, 1986-

2014-01-01

Intervjuu haridusminister Jevgeni Ossinovskiga eelseisvatest ülesannetest hariduse vallas. Küsimusele koalitsioonileppe kohta vastavad Audentese erakooli õpetaja Enn Kirsman, Rocca al Mare kooli aktsiaseltsi juhataja Rein Rebane ja Sakala eragümnaasiumi direktor Jekaterina Gridneva

New Estonian CDs / Igor Garshnek

Index Scriptorium Estoniae

Garšnek, Igor, 1958-

2001-01-01

Uutest heliplaatidest "Eesti portreed", Lepo Sumera. Film Music by Lepo Sumera, Urmas Sisask "Starry Sky Cycle", "Poeme d'amour", "Tango King Astor Piazolla", "Eduard Tubin. Complete Symphonies vol. 2", Henn Rebane "Arabesque", Eino Tamberg "Nocturne"

Jüriöö võit Saue Tammedele / Arvo Saal

Index Scriptorium Estoniae

Saal, Arvo

2008-01-01

Padisel toimunud 49. Jüriöö jooksul võitsid peaauhinna, Kalevipoja kuju kuuendat korda Saue Tammede spordiklubi esimese võistkonna orienteerujad Jürgen Einpalu, Kirti Rebane, Peeter Pihl, Viivi-Anne Soots ja Erkki Aadli

Lasnamäe linnaosavanem laenu tagasimaksega hädas / Eve Heinla

Index Scriptorium Estoniae

Heinla, Eve, 1966-

2005-01-01

Lasnamäe linnaosavanem Oleg Rebane käendas oma firmale Truck & Bus Sales võetud 2,3 miljoni krooni suurust laenu Rahvusvaheliste autovedajate assotsiatsioonist, kuid ei suuda seda nüüd tagasi maksta

Kes kaitseks Eesti ohvitsere NKVD-KGB laimu eest? / Peep Varju

Index Scriptorium Estoniae

Varju, Peep

2008-01-01

Autor polemiseerib Eesti Ekspressis ilmunud artiklitega Eesti endiste ohvitseride kohta, kus käsitletakse nende väidetavat koostööd KGBga. Vaatluse all on ohvitserid Ain Mere, Harald Nugiseks, Alfons Rebane ja Harald Riipalu

Uudised : New Order keerab grungeks. Kaheksas Haapsalu Vanamuusikafestival tulekul. Kaljuste lindistus saab kiita. Janaceki edu flaami ooperis / Harry Liivrand

Index Scriptorium Estoniae

Liivrand, Harry, 1961-

2001-01-01

B. Corgan on ans. New Order uus kitarrist. 4.-8. juulini toimuvast Haapsalu Vanamuusikafestivalist. T. Kaljuste ja Madalamaade Kammerkoori poolt salvestatud S. Tanejevi "The twelve choruses" sai hollandis positiivse vastukaja. L. Janaceki ooperi "Kaval rebane" lavastusest Flaami Ooperis

Kartinõ pribõli v Moskvu taikom / Vahur Koorits

Index Scriptorium Estoniae

Koorits, Vahur, 1981-

2008-01-01

9. detsembril avati Moskvas Zurab Tsereteli galeriis eesti kunstnike näitus ±Paradise is not lost¬. Kuraator Eha Komissarov. Vene tolliametnikud ei lubanud üle piiri Raul Meele ja Villem Jahu teoseid, sest pidasid neid poliitiliselt sobimatuks. Kunstnikud viisid oma tööd Moskvasse isikliku pagasi hulgas. Kommenteerinud Ksenia Repson "Moskvitshi poznakomjatsja s estonskimi hudozhnikami"

Suur kera väikese sees / Kalju Kruusa

Index Scriptorium Estoniae

Kruusa, Kalju, pseud., 1973-

2010-01-01

Tutvustus: Hullunud pilv / Ikkyū Sōjun ; klassikalisest hiina keelest tõlkinud ja kommenteerinud Rein Raud. Tallinn : TLU Press, 2010 ; Lind tulemäe kohal : valik XX sajandi teise poole türgi luulet / tõlkinud Andres Ehin ja Ly Seppel. Tallinn : Kultuurileht, 2010 ; Narain, Kunwar. See ainuke maailm : valitud luuletused. Lelle : Allikaääre, 2010

Käibe kasvu TOP 100

Index Scriptorium Estoniae

2003-01-01

Käibe kasvu TOP 100. 2002. a. netokäibe kasvust Eesti Ehitus OÜ, Russian Estonian Railway Services OÜ, Baltic Pulp & Paper AS-i ja Water Ser AS-i näitel. Diagrammid. Kommenteerivad Selene Rebane ja Rivo Sarapik

Kas ja millistel tingimustel on õpetaja füüsiline sekkumine koolis õigustatud? / Hendrik Agur, Urve Krause, Kairit Seenmaa ... [jt.

Index Scriptorium Estoniae

2009-01-01

Küsimusele vastavad: Gustav Adolfi Gümnaasiumi direktor Hendrik Agur, Pärnu Kuninga tänava Põhikooli direktor Urve Krause, Tallinna Ristiku Põhikooli õppealajuhataja Kairit Seenmaa, Kiili Gümnaasiumi direktor Mihkel Rebane ja Eesti Lastevanemate Liidu juhatuse liige Valdek Rohtma

Avati Deco Galerii Boutique

Index Scriptorium Estoniae

2000-01-01

Eragalerii Deco asutajad Epp ja Tiit Rebane avasid Vana-Posti 2 Deco Galerii Boutique, kus pakutakse vaadata ja müüa minimaali, -graafikat ja vitraaže (loetletud kunstnikke). Kadriorus asunud Deco lõpetas tegevuse rendilepingu lõppemise tõttu

Kuidas sai kirjanik Mart Raud endale kirjanik Albert Kivikase maja? : [Tallinn, Vaarika 3] / Stepan Karja

Index Scriptorium Estoniae

Karja, Stepan

1995-01-01

Vastukaja : Raud, Valda; Raud, Anu. Vastuseks Stepan Karja artiklile 'Kuidas sai kirjanik Mart Raud endale kirjanik Albert Kivikase maja' // Postimees, 1995, 18.apr., lk.7 ; Rebane, Ilme. Alati on raske loobuda armsaks saanud elupaigast // Postimees, 1995, 25.mai, lk.6

Pyriculins A and B, two monosubstituted hex-4-ene-2,3-diols and other phytotoxic metabolites produced by Pyricularia grisea isolated from buffelgrass (Cenchrus ciliaris).

Science.gov (United States)

Masi, Marco; Meyer, Susan; Górecki, Marcin; Mandoli, Alessandro; Di Bari, Lorenzo; Pescitelli, Gennaro; Cimmino, Alessio; Cristofaro, Massimo; Clement, Suzette; Evidente, Antonio

2017-11-01

Pyricularia grisea has been identified as a foliar pathogen on buffelgrass (Cenchrus ciliaris) in North America and was studied as a potential source of phytotoxins for buffelgrass control. Two monosubstituted hex-4-ene-2,3-diols, named pyriculins A and B, were isolated from its culture filtrate organic extract together with (10S,11S)-(-)-epipyriculol, trans-3,4-dihydro-3,4,8-trihydroxy-1(2H)-napthalenone, and (4S)-(+)-isosclerone. Pyriculins A and B were characterized by spectroscopic (essentially nuclear magnetic resonance [NMR], High-resolution electrospray ionization mass spectrometry [HRESIMS]) and chemical methods such as (4E)-1-(4-hydroxy-1,3-dihydroisobenzofuran-1-yl)hex-4-ene-2,3-diols. The relative and absolute configuration of these compounds was determined by a combination of spectroscopic (NMR, electronic circular dichroism [ECD]) and computational tools. When bioassayed in a buffelgrass coleoptile and radicle elongation test, (10S,11S)-(-)-epipyriculol proved to be the most toxic compound. Seed germination was much reduced and slowed with respect to the control and radicles failed to elongate. All five compounds delayed germination, but only (10S,11S)-(-)-epipyriculol was able to prevent radicle development of buffelgrass seedlings. It had no effect on coleoptile elongation, while the other four compounds caused significantly increased coleoptile development relative to the control. © 2017 Wiley Periodicals, Inc.

The IS-ENES climate4impact portal: bridging the CMIP5 and CORDEX data to impact users

Science.gov (United States)

Som de Cerff, Wim; Plieger, Maarten; Page, Christian; Tatarinova, Natalia; Hutjes, Ronald; de Jong, Fokke; Bärring, Lars; Sjökvist, Elin; Vega Saldarriaga, Manuel; Santiago Cofiño Gonzalez, Antonio

2015-04-01

The aim of climate4impact (climate4impact.eu) is to enhance the use of Climate Research Data and to enhance the interaction with climate effect/impact communities. The portal is based on 17 impact use cases from 5 different European countries, and is evaluated by a user panel consisting of use case owners. It has been developed within the IS-ENES European project and is currently operated and further developed in the IS ENES2 project. As the climate impact community is very broad, the focus is mainly on the scientific impact community. Climate4impact is connected to the Earth System Grid Federation (ESGF) nodes containing global climate model data (GCM data) from the fifth phase of the Coupled Model Intercomparison Project (CMIP5) and regional climate model data (RCM) data from the Coordinated Regional Climate Downscaling Experiment (CORDEX). This global network of climate model data centers offers services for data description, discovery and download. The climate4impact portal connects to these services using OpenID, and offers a user interface for searching, visualizing and downloading global climate model data and more. A challenging task is to describe the available model data and how it can be used. The portal informs users about possible caveats when using climate model data. All impact use cases are described in the documentation section, using highlighted keywords pointing to detailed information in the glossary. Climate4impact currently has two main objectives. The first one is to work on a web interface which automatically generates a graphical user interface on WPS endpoints. The WPS calculates climate indices and subset data using OpenClimateGIS/icclim on data stored in ESGF data nodes. Data is then transmitted from ESGF nodes over secured OpenDAP and becomes available in a new, per user, secured OpenDAP server. The results can then be visualized again using ADAGUC WMS. Dedicated wizards for processing of climate indices will be developed in close

Crystal structures of three anhydrous salts of the Lewis base 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU with the ring-substituted benzoic acid analogues 4-aminobenzoic acid, 3,5-dinitrobenzoic acid and 3,5-dinitrosalicylic acid

Directory of Open Access Journals (Sweden)

Graham Smith

2016-03-01

Full Text Available The anhydrous salts of the Lewis base 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU with 4-aminobenzoic acid [1-aza-8-azoniabicyclo[5.4.0]undec-7-ene 4-aminobenzoate, C9H17N2+·C7H6NO2− (I], 3,5-dinitrobenzoic acid [1-aza-8-azoniabicyclo[5.4.0]undec-7-ene 3,5-dinitrobenzoate, C9H17N2+·C7H3N2O6−, (II] and 3,5-dinitrosalicylic acid (DNSA [1-aza-8-azoniabicyclo[5.4.0]undec-7-ene 2-hydroxy-3,5-dinitrobenzoate, C9H17N2+·C7H3N2O7−, (III] have been determined and their hydrogen-bonded structures are described. In both (II and (III, the DBU cations have a common disorder in three of the C atoms of the six-membered ring moieties [site-occupancy factors (SOF = 0.735 (3/0.265 (3 and 0.686 (4/0.314 (4, respectively], while in (III, there is additional rotational disorder in the DNSA anion, giving two sites (SOF = 0.72/0.28, values fixed for the phenol group. In the crystals of (I and (III, the cation–anion pairs are linked through a primary N—H...Ocarboxyl hydrogen bond [2.665 (2 and 2.869 (3 Å, respectively]. In (II, the ion pairs are linked through an asymmetric three-centre R12(4, N—H...O,O′ chelate association. In (I, structure extension is through amine N—H...Ocarboxyl hydrogen bonds between the PABA anions, giving a three-dimensional structure. The crystal structures of (II and (III are very similar, the cation–anion pairs being associated only through weak C—H...O hydrogen bonds, giving in both overall two-dimensional layered structures lying parallel to (001. No π–π ring associations are present in any of the structures.

Enantioselective synthesis of possible diastereomers of heptadeca-1-ene-4,6-diyne-3,8,9,10-tetrol; putative structure of a conjugated diyne natural product isolated from Hydrocotyle leucocephala.

Science.gov (United States)

Prasad, Kavirayani R; Swain, Bandita

2011-04-01

Enantioselective synthesis of possible diastereomers of heptadeca-1-ene-4,6-diyne-3,8,9,10-tetrol, a structure proposed for the natural product isolated from Hydrocotyle leucocephala is accomplished. The reported spectral data of the natural product did not match those of any of the isomers that were synthesized and established that the structure proposed for the natural product is not correct and requires revision.

Imetabane väljapanek toob Kumu saali kogu maailma looduse kirevuse / Rein Maran

Index Scriptorium Estoniae

Maran, Rein, 1931-

2006-01-01

Rahvusvahelise fotokonkursi näitusest "Loodusfoto 2005" Kumu suures saalis. Briti Loodusloomuuseumi ja ajakirja BBC Wildlife Magazine korraldatud fotokonkursist. Lähemalt võidutöödest: Alexander Mustard (Suurbritannia) "Riffahvenate parv", Manuel Presti (Itaalia) "Taevane jaht", Bence Mate (Ungari) "Haigutav rebane", Thorsten Milse (Saksamaa) "Polaarretk"

Agar pronkssõduriga võitleja sai kanepisuitsetamise eest trahvi / Katrin Rohtla, Siim Randla

Index Scriptorium Estoniae

Rohtla, Katrin, 1966-

2006-01-01

Aktiivse pronkssõduri vastasena tuntust kogunud Isamaaliidu liige Kalev Rebane sai Läänemaal Peraküla rannas kanepi suitsetamise eest politseilt 9000 krooni trahvi. Isamaa ja Res Publica Liidu liikmed on teinud ettepaneku noormees erakonnast välja arvata. Lisa: Mille eest koostati protokoll?

Stereochemistry of 16a-Hydroxyfriedelin and 3-Oxo-16-methylfriedel-16-ene Established by 2D NMR Spectroscopy

Directory of Open Access Journals (Sweden)

Vagner Fernandes Knupp

2009-02-01

Full Text Available Friedelin (1, 3b-friedelinol (2, 28-hydroxyfriedelin (3, 16a-hydroxyfriedelin (4, 30-hydroxyfriedelin (5 and 16a,28-dihydroxyfriedelin (6 were isolated through fractionation of the hexane extract obtained from branches of Salacia elliptica. After a week in CDCl3 solution, 16a-hydroxyfriedelin (4 reacted turning into 3-oxo-16-methylfriedel-16-ene (7. This is the first report of a dehydration followed by a Nametkin rearrangement of a pentacyclic triterpene in CDCl3 solution occurring in the NMR tube. These seven pentacyclic triterpenes was identified through NMR spectroscopy and the stereochemistry of compound 4 and 7 was established by 2D NMR (NOESY spectroscopy and mass spectrometry (GC-MS. It is also the first time that all the 13C-NMR and 2D NMR spectral data are reported for compounds 4 and 7.

Cyclohex-1-ene carboxylic acids: synthesis and biological evaluation of novel inhibitors of human 5 alpha reductase.

Science.gov (United States)

Baston, Eckhard; Salem, Ola I A; Hartmann, Rolf W

2003-03-01

In search of novel nonsteroidal mimics of steroidal inhibitors of 5 alpha reductase, 4-(2-phenylethyl)cyclohex-1-ene carboxylic acids 1-5 were synthesized with different substituents in para position of the phenyl ring (1: N, N-diisopropylcarbamoyl, 2: phenyl, 3: phenoxy, 4: benzoyl, and 5: benzyl). The principal synthetic approach for the desired compounds consisted of a Wittig olefination between 1, 4-dioxaspiro [4.5]-decane-8-carbaldehyde (4g and the appropriate phosphonium salts. The compounds were tested for inhibition of human 5 alpha reductase isozymes 1 and 2 using DU 145 cells and preparations from prostatic tissue, respectively. They turned out to be good inhibitors of the prostatic isozyme 2 with compound 1 being the most potent one (IC(50) = 760 nM). Isozyme 1 was only slightly inhibited. It is concluded that the novel structures are appropriate for being further optimized, aiming at the development of a novel drug for the treatment of benign prostatic hyperplasia.

Res Publica viskab Oleg Rebase välja

Index Scriptorium Estoniae

2006-01-01

Res Publica Tallinna piirkonna juhatus leidis, et Oleg Rebane läks Keskerakonna provokatsiooniga kaasa minnes vastuollu Res Publica põhimõtetega. Tallinna linnapea Jüri Ratase suhtes algatatud umbusaldushääletuse põhjustest. Sven Sester vastab küsimusele, mis seotud Oleg Rebase ja Tõnis Bittmani juhtumiga

Superhydrophobic and Slippery Lubricant-Infused Flexible Transparent Nanocellulose Films by Photoinduced Thiol-Ene Functionalization.

Science.gov (United States)

Guo, Jiaqi; Fang, Wenwen; Welle, Alexander; Feng, Wenqian; Filpponen, Ilari; Rojas, Orlando J; Levkin, Pavel A

2016-12-14

Films comprising nanofibrillated cellulose (NFC) are suitable substrates for flexible devices in analytical, sensor, diagnostic, and display technologies. However, some major challenges in such developments include their high moisture sensitivity and the complexity of current methods available for functionalization and patterning. In this work, we present a facile process for tailoring the surface wettability and functionality of NFC films by a fast and versatile approach. First, the NFC films were coated with a layer of reactive nanoporous silicone nanofilament by polycondensation of trichlorovinylsilane (TCVS). The TCVS afforded reactive vinyl groups, thereby enabling simple UV-induced functionalization of NFC films with various thiol-containing molecules via the photo "click" thiol-ene reaction. Modification with perfluoroalkyl thiols resulted in robust superhydrophobic surfaces, which could then be further transformed into transparent slippery lubricant-infused NFC films that displayed repellency against both aqueous and organic liquids with surface tensions as low as 18 mN·m -1 . Finally, transparent and flexible NFC films incorporated hydrophilic micropatterns by modification with OH, NH 2 , or COOH surface groups, enabling space-resolved superhydrophobic-hydrophilic domains. Flexibility, transparency, patternability, and perfect superhydrophobicity of the produced nanocellulose substrates warrants their application in biosensing, display protection, and biomedical and diagnostics devices.

Mõned mõtted "suvelugemisest" ja suvelugemisest / Peeter Helme

Index Scriptorium Estoniae

Helme, Peeter, 1978-

2009-01-01

Tutvustatakse ja soovitatakse raamatuid: Aleksejev, Tiit. Palveränd : lugu Esimesest ristisõjast. Tallinn : Varrak, 2008 ; Rebane, Kristi. Minu oma. Tallinn : Tänapäev, 2009 ; Kaints, Holger. Lennukivaatleja. Tallinn : Kultuurileht, 2009 ; Kehlmann, Daniel. Maailma mõõtmine. Tartu : Atlex, c2008 ; Zafón, Carlos Ruiz. Tuule vari. Tallinn : Varrak, 2008

Inspection and monitoring plan, contaminated groundwater seeps 317/319/ENE Area, Argonne National Laboratory

International Nuclear Information System (INIS)

1996-01-01

During the course of completing the Resource Conservation and Recovery Act (RCRA) Facility Investigation (RFI) in the 317/319/East-Northeast (ENE) Area of Argonne National Laboratory-East (ANL-E), groundwater was discovered moving to the surface through a series of groundwater seeps. The seeps are located in a ravine approximately 600 ft south of the ANL-E fence line in Waterfall Glen Forest Preserve. Samples of the seep water were collected and analyzed for selected parameters. Two of the five seeps sampled were found to contain detectable levels of organic contaminants. Three chemical species were identified: chloroform (14--25 microg/L), carbon tetrachloride (56--340 microg/L), and tetrachloroethylene (3--6 microg/L). The other seeps did not contain detectable levels of volatile organics. The nature of the contaminants in the seeps will also be monitored on a regular basis. Samples of surface water flowing through the bottom of the ravine and groundwater emanating from the seeps will be collected and analyzed for chemical and radioactive constituents. The results of the routine sampling will be compared with the concentrations used in the risk assessment. If the concentrations exceed those used in the risk assessment, the risk calculations will be revised by using the higher numbers. This revised analysis will determine if additional actions are warranted

Estimación del impacto económico de los museos a través de las nuevas tecnologías de la información: el caso del museo Ene.Térmica

Directory of Open Access Journals (Sweden)

Vicente COLL-SERRANO

Full Text Available Cada vez es más necesario poner de relieve el potencial de la cultura como motor del desarrollo económico y su capacidad para generar ingresos y crear empleo. Por este motivo, en este trabajo se evalúa el impacto económico del museo Ene.Térmica sobre el territorio en el que se ubica, Ponferrada (Comunidad de Castilla y León, España. Para lograr este objetivo, la estimación de los distintos tipos de efectos necesarios para determinar el impacto de las actividades económicas vinculas a la existencia de Ene.Térmica se realiza, en base a la metodología de las Tablas Input-Output, mediante la herramienta Impactrimonio, una aplicación implementada sobre una plataforma web. Los resultados obtenidos indican que entre las actividades del museo y los flujos de demanda desplegados por el efecto arrastre de los visitantes se generó, entre los años 2011 y 2012, un incremento de la producción de más de 15 millones de euros, un incremento de las rentas de la población de casi 10 millones de euros y un aumento de la ocupación de 327 empleos.

Mazda6 lennutas Mazda-müüjad esiridadesse / Tõnu Tramm

Index Scriptorium Estoniae

Tramm, Tõnu, 1968-

2003-01-01

Sõidukimüüjate TOP 40 3. koht. Vilojett AS-i juhatuse esimees Ahti Rebane ja tegevdirektor Kalle Kaldjärv nimetavad edu põhjustena turunduskampaaniat, automudeli Mazda6 müügirekordit ja Tallinnas valminud kasutatud autode müügisalongi. Lühiülevaade tegevusplaanist ja olulisematest sündmustest 1996-2003. Diagramm: Vilojett tõusuteel

Theoretical study on the photolysis mechanism of 2,3-diazabicyclo[2.2.2]oct-2-ene.

Science.gov (United States)

Chen, Hui; Li, Shuhua

2005-09-28

A CASPT2/CASSCF study has been carried out to investigate the mechanism of the photolysis of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) under direct and triplet-sensitized irradiation. By exploring the detailed potential energy surfaces including intermediates, transition states, conical intersections, and singlet/triplet crossing points, for the first excited singlet (S(1)) and the low-lying triplet states (T(1), T(2), and T(3)), we provide satisfactory explanations of many experimental findings associated with the photophysical and photochemical processes of DBO. A key finding of this work is the existence of a significantly twisted S(1) minimum, which can satisfactorily explain the envelope of the broad emission band of DBO. It is demonstrated that the S(1) (n-pi*) intermediate can decay to the T(1) (n-pi*) state by undergoing intersystem crossing (rather inefficient) to the T(2) (pi-pi*) state followed by internal conversion to the T(1) state. The high fluorescence yield and the extraordinarily long lifetime of the singlet excited DBO are due to the presence of relatively high barriers, both for intersystem crossing and for C-N cleavage. The short lifetime of the triplet DBO is caused by fast radiationless decay to the ground state.

Thiol-ene immobilisation of carbohydrates onto glass slides as a simple alternative to gold-thiol monolayers, amines or lipid binding.

Science.gov (United States)

Biggs, Caroline I; Edmondson, Steve; Gibson, Matthew I

2015-01-01

Carbohydrate arrays are a vital tool in studying infection, probing the mechanisms of bacterial, viral and toxin adhesion and the development of new treatments, by mimicking the structure of the glycocalyx. Current methods rely on the formation of monolayers of carbohydrates that have been chemically modified with a linker to enable interaction with a functionalised surface. This includes amines, biotin, lipids or thiols. Thiol-addition to gold to form self-assembled monolayers is perhaps the simplest method for immobilisation as thiolated glycans are readily accessible from reducing carbohydrates in a single step, but are limited to gold surfaces. Here we have developed a quick and versatile methodology which enables the use of thiolated carbohydrates to be immobilised as monolayers directly onto acrylate-functional glass slides via a 'thiol-ene'/Michael-type reaction. By combining the ease of thiol chemistry with glass slides, which are compatible with microarray scanners this offers a cost effective, but also useful method to assemble arrays.

Investigation of the fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) by certain substituted uracils

Energy Technology Data Exchange (ETDEWEB)

Anbazhagan, V. [School of Chemistry, Bharathidasan University, Tiruchirappalli 620024, Tamil Nadu (India); Renganathan, R. [School of Chemistry, Bharathidasan University, Tiruchirappalli 620024, Tamil Nadu (India)], E-mail: rrengas@yahoo.com

2009-04-15

The fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) by a series of uracils has been studied in water and acetonitrile solvents using steady-state and time-resolved fluorescence techniques. The steady-state fluorescence quenching technique has been performed in three different pHs (i.e. 4, 8 and 12). The bimolecular quenching rate constant (k{sub q}) increases with increase in pH of uracils. In acidic pH, a pure hydrogen atom abstraction is proposed as the quenching mechanism. This is supported by a pronounced solvent deuterium isotope effect. Electron transfer from the anionic form of uracil to the excited state of DBO is proposed as a mechanism for quenching in basic pH on the basis of highly exergonic thermodynamics obtained from the Rehm-Weller equation. The variation of k{sub q} is explained on the basis of the electronic effect of substitution in uracils as well.

Investigation of the fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) by certain substituted uracils

International Nuclear Information System (INIS)

Anbazhagan, V.; Renganathan, R.

2009-01-01

The fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) by a series of uracils has been studied in water and acetonitrile solvents using steady-state and time-resolved fluorescence techniques. The steady-state fluorescence quenching technique has been performed in three different pHs (i.e. 4, 8 and 12). The bimolecular quenching rate constant (k q ) increases with increase in pH of uracils. In acidic pH, a pure hydrogen atom abstraction is proposed as the quenching mechanism. This is supported by a pronounced solvent deuterium isotope effect. Electron transfer from the anionic form of uracil to the excited state of DBO is proposed as a mechanism for quenching in basic pH on the basis of highly exergonic thermodynamics obtained from the Rehm-Weller equation. The variation of k q is explained on the basis of the electronic effect of substitution in uracils as well

The photochemical reaction of 1,1-dicyano-3-phenylbut-1-ene. Simultaneous occurrence of p-methane and di-p-methane rearrangements

Directory of Open Access Journals (Sweden)

Silva Francisco A. da

1999-01-01

Full Text Available The direct photolysis of 1,1-dicyano-3-phenylbut-1-ene (3-MDCN was investigated at room temperature in solvents of different polarities (hexane, dichloromethane and acetonitrile. Cyclopropanes arising from both the di-pi-methane and pi-methane (1,2-H migration processes were obtained as photoproducts. The structures of the products were elucidated by ¹H-NMR, GC/MS, IR and chromatography. Relative quantum yield determination and GC analysis of sequential irradiations gave evidence that: i no secondary reactions occur, even at high conversions; ii the di-pi-methane rearrangement is significantly more affected by the solvent variation than the pi-methane reaction. Photosensitization with acetophenone or acetone did not yield any observable products. The existence of the simultaneous mechanisms and the observed effects were considered as evidence of a possible differentiation between localized and delocalized excitation on the excited state surface.

Pärnu Keskkonnahariduskeskus = Pärnu Environmental Education Centre

Index Scriptorium Estoniae

2015-01-01

Pärnu Keskkonnahariduskeskus A.H. Tammsaare puiestee 57, valminud 2013. Arhitektuurivõistlus 2006, jagatud III koht. Võistlustöö autorid Maarja Kask, Karli Luik, Ralf Lõoke (Salto Arhitektuuribüroo). Arhitektid Maarja Kask, Karli Luik, Ralf Lõoke, Helin Kukk, Andro Mänd, Helen Rebane, Margus Tamm. Pärnumaa püsinäituse kujundus Malle Jürgenson, Krista Lepland (Laika, Belka & Strelka)

Vabadusvõitluse veteran soovitab igale noorele aastakese Siberit / Villu Päärt

Index Scriptorium Estoniae

Päärt, Villu, 1972-

2004-01-01

Vt. ka Infopress, 27.02.2004, lk. 34, 131. Muuseumi "KGB kongid" loojast ja õpilasvabadusvõitlejast Päivu Kullist, kes vangistati 1950. aastal ning saadeti asumisele Siberisse. Lisatud sõnum "President autasustab Eesti iseseisvuspäeva puhul seitset ammust vabadusvõitlejat", kus ordeni saajatena on loetletud Aime Espenberg, Valev Kaska, Päivu Kull, Juhan Lumiste, Mango Daniel, Johannes Kivimäe, Lea Rebane

Olean-18-ene triterpenoids from Celastraceae species inhibit HIV replication targeting NF-kB and Sp1 dependent transcription.

Science.gov (United States)

Osorio, Alex A; Muñóz, Alejandro; Torres-Romero, David; Bedoya, Luis M; Perestelo, Nayra R; Jiménez, Ignacio A; Alcamí, José; Bazzocchi, Isabel L

2012-06-01

In the present study we report the isolation of nine new olean-18-ene triterpenes (1-9), along with three known ones (10-12), from Cassine xylocarpa and Maytenus jelskii. Their stereostructures have been elucidated on the basis of spectroscopic analysis, including 1D and 2D NMR techniques (COSY, ROESY, HSQC and HMBC), and spectrometric methods. The natural compounds and derivatives 13-15 have been tested for their potential as inhibitors of human immunodeficiency virus type 1 replication. Five compounds from this series displayed potent antiviral activity with IC(50)s in the micromolar range (1, 3, 4, 7 and 8) being 1 and 8 the most active compounds. The target of these compounds was different from antiretroviral drugs currently licensed as they act as inhibitors of enhancer-dependent transcription. The structure-activity relationships were established based on the regiosubstitution and oxidation degree of the triterpene scaffold, revealing that these aspects were able to modulate the selectivity and intensity of HIV inhibition. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

1,4a-Dimethyl-6-methyl-ene-5-(5,5,6,6-tetra-cyano-2-methyl-cyclo-hex-2-enylmeth-yl)deca-hydro-naphthalene-1-carboxylic acid: a trans-communic acid derivative.

Science.gov (United States)

Rejouani, Nezha; Auhmani, Aziz; Ait Itto, My Youssef; Benharref, Ahmed; Daran, Jean-Claude

2008-01-18

In the search for cancer chemopreventive agents, we have studied the Diels-Alder reaction of trans-communic acid with tetra-cyano-ethyl-ene in the presence of SiO(2) as catalyst. The title cycloadduct, C(26)H(30)N(4)O(2), was obtained in 75% yield. The mol-ecules are arranged in pairs through O-H⋯O hydrogen bonds, forming an R(2) (2)(8) ring motif. Both the fused cyclohexyl rings adopt a chair conformation, whereas the nonfused ring adopts a half-chair conformation.

President Ilves sattus YouTube'i tarkust jagama / Tõnu Lilleorg

Index Scriptorium Estoniae

Lilleorg, Tõnu

2008-01-01

President Toomas Hendrik Ilvese majandusteemalisest videoläkitusest portaalis YouTube. Arvamust avaldavad Balti meedia- ja filmikooli õppedirektor Hagi Šein, Riigikogu liige Vilja Savisaar ja kommunikatsioonikonsultant Raul Rebane. Vt. ka juhtkiri lk. 12: Kes tegi? Ilves ise tegi! Õhtulehe arvates vastutab majanduskriisi eest ka president ise. Lisatud karikatuur. Juhtkiri ilmunud ka: Molodjož Estonii 11. dets. 2008, lk. 4, pealk.: Kto vinovat?

Näitused / Mari Sobolev

Index Scriptorium Estoniae

Sobolev, Mari, 1968-

1998-01-01

Kunstihoone ja Rotermanni soolaladu: "Kujundid, objektid, stseenid - vaatenurki prantsuse kunstile alates 1978. aastast"; Sammas-galerii: Tiiu Rebane ja Karl Nagel "Tänapäeva müüt"; Raatuse galerii: Elo Järv "Saavad uuteks liblikateks" (nahakunst); Tammsaare muuseum: "Mis jääb mällu" (sissevaade Saksamaa ajalukku ajavahemikul 1933-1949); Hotell "Olümpia" Forte saal: Gabor Dienesi personaalnäitus (maalid)

Kiikuv maja / Anu Arm

Index Scriptorium Estoniae

Arm, Anu

2006-01-01

Eesti Kunstiakadeemia esimese kursuse arhitektuuriüliõpilaste II semestri töö. Juhendaja arhitekt Andres Alver, ehitamise Pedaspeale organiseeris suvepraktika juhendaja arhitekt Jaan Tiidemann. Autor Anu Arm, kaasa töötasid ja valmis ehitasid: Ott Alver, Maarja Elm, Mari Hunt, Alvin Järving, Marten Kaevats, Riho Kerge, Reedik Poopuu, Anu Põime, Helen Rebane, Kaisa Saarva, Martin Tago, Reet Volt. Valmis: 19. VIII 2006

Maailma loodusfoto Kumus

Index Scriptorium Estoniae

2006-01-01

18.10-12.11 Kumu Kunstimuuseumis avatud 80 loodusfoto näitus, mille korraldajad olid Briti Loodusloomuuseum ja ajakiri BBC Wildlife Magazine. Illustratsioonidena "Loodusfoto 2005" üldvõitja Manuel Presti "Taevane jaht", loomaportreede kategooria võitja Alexander Mustard'i "Riffahvenate parv", imetajate käitumise kategooria II koht Thorsten Milse "Polaarretk" ja noortele fotograafidele mõeldud Eric Hoskingi kategooria võitja Bence Maté "Haigutav rebane"

The synthesis of weak acidic type hybrid monolith via thiol-ene click chemistry and its application in hydrophilic interaction chromatography.

Science.gov (United States)

Zeng, Jiao; Liu, Shengquan; Wang, Menglin; Yao, Shouzhuo; Chen, Yingzhuang

2017-05-01

In this work, a porous structure and good permeability monolithic column was polymerized in UV transparent fused-silica capillaries via photo-initiated thiol-ene click polymerization of 2,4,6,8-tetravinyl-2,4,6,8-tetramethylcyclotetrasiloxane (TMTVS), pentaerythritol tetra(3-mercaptopropionate)(PETMP), itaconic acid, respectively, in the presence of porogenic solvents (tetrahydrofuranand methanol) and an initiator (2,2-dimethoxy-2-phenylacetophenone) (DMPA) within 30 min. The physical properties of this monolith were characterized by scanning electron microscopy (SEM), Fourier transform infrared (FT-IR) spectroscopy and nitrogen adsorption/desorption measurements. For an overall evaluation of the monolith in chromatographic application, separations of polycyclic aromatic hydrocarbons (PAHs), phenols, amides and bases were carried out. The column efficiency of this monolith could be as high as 112 560 N/m. It also possesses a potential application in fabrication of monoliths with high efficiency for c-LC. In addition, the resulting monolithic column demonstrated the potential use in analysis of environment waters. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Comment on "An unexpected formation of the novel 7-oxa-2-azabicyclo[2.2.1]hept-5-ene skeleton during the reaction of furfurylamine with maleimides and their bioprospection using a zebrafish embryo model" by C. E. Puerto Galvis and V. V. Kouznetsov, Org. Biomol. Chem., 2013, 11, 407.

Science.gov (United States)

Zubkov, F I; Kvyatkovskaya, E A; Nikitina, E V; Amoyaw, P N-A; Kouznetsov, V V; Lazarenko, V A; Khrustalev, V N

2017-08-02

It has been proved that the reaction between furfuryl amines and N-R-maleimides leads to the formation of aza-Michael addition products - 3-(furylmethylamino)-N-R-pyrrolidine-2,5-diones, instead of 7-oxa-2-azabicyclo[2.2.1]hept-5-enes, as this journal reported previously.

EK(b)P Keskkomitee VIII pleenumi stenogramm / tõlk. Mart Arold, tõlk. Jaan Isotamm

Index Scriptorium Estoniae

1999-01-01

EK(b)P Keskkomitee VIII pleenum, 21.-23. märts 1950. Sõnavõtud: N. Karotamm, P. Ponomarenko, I. Käbin, V. Kuusik, A. Jaanus, V. Hiznjakov, E. Ristimägi, I. Suija, H. Ajo, A. Meri, G. Abels, M. Assin, G. Latõshov, Rumjantsev, Müürisepp. Kommenteerinud Viktor Niitsoo. Algus: Akadeemia (1998) nr. 12, lk. 2655-2683 ; Järg nr.2;3;4;5;6;7;8;9;10 lk.415-446;639-670;863-894;1087-1118;1310-1342;1534-1566;1759-1790;2017-2048;2220-2256

Вышел первый том переписки Лотмана с Егоровым

Index Scriptorium Estoniae

2012-01-01

Tutvustus: Лотман, Юрий Михайлович ; Минц, Зара Гиршевна ; Егоров, Борис Федорович. Переписка 1954-1965 / teksti on ette valmistanud ja kommenteerinud Boriss Jegorov, Tatjana Kuzovkina, Nikolai Poseljagin, eessõna Boriss Jegorov. Tallinn : Tallinna Ülikooli Kirjastus, 2012. (Bibliotheca Lotmaniana)

Poly(allyl methacrylate) functionalized hydroxyapatite nanocrystals via the combination of surface-initiated RAFT polymerization and thiol-ene protocol: a potential anticancer drug nanocarrier.

Science.gov (United States)

Bach, Long Giang; Islam, Md Rafiqul; Vo, Thanh-Sang; Kim, Se-Kwon; Lim, Kwon Taek

2013-03-15

Hydroxyapatite nanocrystals (HAP NCs) were encapsulated by poly(allyl methacrylate) (PolyAMA) employing controlled surface-initiated reversible addition-fragmentation chain transfer (SI-RAFT) polymerization of allyl methacrylate to afford HAP-PolyAMA nanohybrids. The subsequent thiol-ene coupling of nanohybrids with 2-mercaptosuccinic acid resulted HAP-Poly(AMA-COOH) possessing multicarboxyl group. The formation of the nanohybrids was confirmed by FT-IR and EDS analyses. The TGA and FE-SEM investigation were further suggested the grafting of PolyAMA onto HAP NCs. The utility of the HAP-PolyAMA nanohybrid as drug carrier was also explored. The pendant carboxyl groups on the external layers of nanohybrids were conjugated with anticancer drug cisplatin to afford HAP-Poly(AMA-COOH)/Pt complex. The formation of the complex was confirmed by FT-IR, XPS, and FE-SEM. In vitro evaluation of the synthesized complex as nanomedicine revealed its potential chemotherapeutic efficacy against cancer cell lines. Copyright © 2012 Elsevier Inc. All rights reserved.

Design and fabrication of uniquely shaped thiol-ene microfibers using a two-stage hydrodynamic focusing design.

Science.gov (United States)

Boyd, Darryl A; Shields, Adam R; Howell, Peter B; Ligler, Frances S

2013-08-07

Microfluidic systems have advantages that are just starting to be realized for materials fabrication. In addition to the more common use for fabrication of particles, hydrodynamic focusing has been used to fabricate continuous polymer fibers. We have previously described such a microfluidics system which has the ability to generate fibers with controlled cross-sectional shapes locked in place by in situ photopolymerization. The previous fiber fabrication studies produced relatively simple round or ribbon shapes, demonstrated the use of a variety of polymers, and described the interaction between sheath-core flow-rate ratios used to control the fiber diameter and the impact on possible shapes. These papers documented the fact that no matter what the intended shape, higher flow-rate ratios produced rounder fibers, even in the absence of interfacial tension between the core and sheath fluids. This work describes how to fabricate the next generation of fibers predesigned to have a much more complex geometry, as exemplified by the "double anchor" shape. Critical to production of the pre-specified fibers with complex features was independent control over both the shape and the size of the fabricated microfibers using a two-stage hydrodynamic focusing system. Design and optimization of the channels was performed using finite element simulations and confocal imaging to characterize each of the two stages theoretically and experimentally. The resulting device design was then used to generate thiol-ene fibers with a unique double anchor shape. Finally, proof-of-principle functional experiments demonstrated the ability of the fibers to transport fluids and to interlock laterally.

Bon appetite! / Mari-Liis Rebane

Index Scriptorium Estoniae

Rebane, Mari-Liis

2009-01-01

Pimedate Ööde 13. filmifestivali alafestivali Animated Dreams täispikki animafilme: Austraalia "Mary ja Max" (režissöör Elliot, Adam), Rootsi-Taani-Norra "Metropia" (režissöör Tarik Saleh), Iisraeli-Austraalia "9,99 dollarit" (režissöör Tatia Rosenthal)

Aasta betoonehitis 2002 / Enno Rebane

Index Scriptorium Estoniae

Rebane, Enno, 1964-

2003-01-01

Betoonehitis 2002 - Tartu vangla, Kalle Rõõmuse Arhitektuuribüroo (projekteerija EstKONSULT, ehitaja AS Skanska EMV). Eriauhinnad: arhitektuurse lahenduse eest - Erki Valdre, Tuvi t. 12 korterelamud Tallinnas; projekteerijale - Eesti Projekt, Linnamäe hüdroelektrijaama taastamine (arhitekt Raine Karp); ehitusmaterjalitootjale - E-Betoonelement, STT katuseelement (Nefab Eesti AS pakenditehas, arhitektuurne lahendus - Tõnis Tarbe Arhitektuuribüroo)

Peer Gynti tagasitulek / Hilve Rebane

Index Scriptorium Estoniae

Rebane, Hilve, 1938-2012

1999-01-01

Arvustus: Ibsen, Henrik. Peer Gynt / tõlkinud Marie Under. 2. tr. Tallinn : Eesti Raamat, 1998. Ka "Peer Gynti" mõjutusi eesti kirjanduses: August Gailiti, Marie Underi, A. H. Tammsaare ja eriti Karl Ristikivi loomingus

Õnnelik Cecilia / Peeter Rebane

Index Scriptorium Estoniae

Rebane, Peeter, 1973-

2005-01-01

Pärnu 19. dokumentaal- ja antropoloogiafilmide festivalil nähtavatest dokumentaalfilmidest jõuab teleekraanile seitse filmi armastusest ja abielust. Filme arvustavad Eesti kultuuri- ja ühiskonnategelased. Dokumentaalfilm "Isainstinkt", režissöör Murray Nossel

Seisuslikud kohtud : talurahvakohtud / Ilmar Rebane

Index Scriptorium Estoniae

Rebane, Ilmar, 1907-2001

1982-01-01

Mõisniku kohus ja kodukari, adra- ehk haagikohus, sillakohus, mõisakohus, asehalduskord, alam-maakohus, alam- ja ülemkorrakohus, vallakohus, kihelkonnakohus, kihelkonna politseikohus, mõisapolitsei, kogukonnapolitsei, kreisikohus, ülem-talurahvakohus. Lisatud väljavõtteid regulatiivist "Iggaüks"

Lastekasvatuseks parim riik / Marit Rebane

Index Scriptorium Estoniae

Rebane, Marit

2016-01-01

2016. aasta aprillis avaldatud UNICEFi ettekandes võrreldakse laste heaolu 41 Euroopa Liidu ja OECD riigis. Kokku on võetud laste heaolu neljas valdkonnas: sissetulekud, hariduslik ja tervislik ebavõrdsus ning ebavõrdsus eluga rahulolus

Korruptsiooni bioloogilised juured / Jaak Rebane

Index Scriptorium Estoniae

Rebane, Jaak

1999-01-01

Kuritarvitusele aitavad viia inimese teatud omadused, nagu egoism, piiratus, ahnus, jultumus, tarbimismentaliteet, tõusiklikkus. Korrumptantsaab varumistungi ajel ebaeetilisest käitumisest hoopis positiivse emotsiooni

Clinical efficacy of implementing Bio Immune(G)ene MEDicine in the treatment of chronic asthma with the objective of reducing or removing effectively corticosteroid therapy: A novel approach and promising results.

Science.gov (United States)

Glady, Gilbert

2018-06-01

Asthma is one of the diseases that demonstrates a wide range of variation in its clinical expression, in addition to an important heterogeneity in the pathophysiological mechanisms present in each case. The ever-increasing knowledge of the molecular signalling routes and the development of the Bio Immune(G)ene Medicine [BI(G)MED] therapy in line with this knowledge has revealed a whole novel potential set of self-regulation biological molecules, that may be used to promote the physiological immunogenic self-regulation mechanisms and re-establish the homeostatic balance at a genomic, proteomic and cellular level. The aim of the present study is to demonstrate that the sublingual use of a therapeutic protocol based on BI(G)MED regulatory BIMUREGs in the treatment of chronic asthma may reduce or suppress corticosteroid therapy and avoid its harmful side effects which some patients suffer when using this treatment on a long-term basis. The clinical efficacy of BI(G)MED for chronic asthma was evaluated through a multi-centre study carried out in 2016 implementing a 6-month BI(G)MED treatment protocol for Bronchial Asthma. A total of 61 patients from private medical centres and of European countries including Germany, Austria, France, Belgium and Spain participated. The manuscript describes in detail the clinical efficacy of Bio Immune(G)ene regulatory BI(G)MED treatment protocol that allows the reduction or total removal of the corticosteroid dose in patients with chronic asthma. No adverse reactions were observed. The BI(G)MED regulatory therapy brings novel therapeutic possibilities as an effective and safe treatment of chronic asthma. BI(G)MED was demonstrated to significantly reduce asthma severity when parameter compositions were all analysed by categorical outcomes. Therefore, it is considered a good therapeutic alternative for patients who respond poorly to steroids.

Reaction of singlet-excited 2,3-diazabicyclo[2.2.2]oct-2-ene and tert-butoxyl radicals with aryl-substituted benzofuranones.

Science.gov (United States)

Lundgren, Cecilia Vannesjö; Koner, Apurba L; Tinkl, Michael; Pischel, Uwe; Nau, Werner M

2006-03-03

5,7-Di-tert-butyl-3-aryl-3H-benzofuran-2-ones are lactones with potential antioxidant activity, owing to their abstractable benzylic C-H hydrogens. The fluorescence quenching of the azoalkane 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO), an established probe for the hydrogen-donor propensity of chain-breaking antioxidants, was investigated for 16 aryl-substituted benzofuranone derivatives [m,m-(CF3)2, p-CN, m-CN, p-CF3, p-COOCH3, m-CF3, p-Cl, p-F, H, m-CH3, p-CH3, m,p-(CH3)2, p-OCH3, o-CH3, o-CF3, o,m-(CH3)2]. Analysis of the rate data in terms of a linear free energy relationship yielded a reaction constant of rho = +0.35. This implies that n,pi*-excited DBO acts as nucleophilic species. In contrast, hydrogen abstraction of tert-butoxyl radicals from the benzofuranones was accelerated by electron-donating substituents (rho = -0.23), in conformity with the electrophilic character of oxygen-centered alkoxyl radicals. Possible implications for the optimization of the hydrogen-donor propensity of antioxidants through structural variation are discussed.

Gailit protesteerib : [August Gailiti kiri Valev Uibopuule 14. okt. 1956] / August Gailit

Index Scriptorium Estoniae

Gailit, August, 1891-1960

1998-01-01

Leonid Treti mälestuste käsikirjast 'A. H. Tammsaare, nagu teda tundsin'. Vastukajad: Siimisker, Leenu. Kultuuri, enam tekstikriitilist kultuuri // Sirp (1998) 13. märts, lk. 18-19 ; Treier, Elem. Klassiku teenimise kibe leib // Sirp (1998) 17. apr., lk. 14 ; Rebane, Hilve. Isikuloolisi lisandusi A. H. Tammsaare tundmisesse // Keel ja Kirjandus (1998) nr. 5, lk. 343-345 ; Kronberg, Janika. Kaanonid ja apokrüüfid // Keel ja Kirjandus (1998) nr. 8, lk. 563-564

Investigations on the fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene by certain flavonoids.

Science.gov (United States)

Anbazhagan, V; Kalaiselvan, A; Jaccob, M; Venuvanalingam, P; Renganathan, R

2008-05-29

The fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) by seven flavonoids namely flavone, flavanone, quercetin, rutin, genistein, diadzein and chrysin has been investigated in acetonitrile and dichloromethane solvents. The bimolecular quenching rate constants lie in the range of 0.09-5.75 x 10(9)M(-1)s(-1) and are explained in terms of structure of the flavonoids studied. The reactivity of flavonoids are in the order: quercetin>rutin>genistein>diadzein>chrysin>flavone>flavanone. The quenching rate constants (k(q)) increase with increase in the number of -OH groups. The endergonic thermodynamic values of DeltaG(et) reveal that electron transfer quenching mechanism can be ruled out. Bond dissociation enthalpy calculations reveal that the position of -OH is important. Further in vitro-antioxidant activities of flavonoids were evaluated with rat liver catalase by gel electrophoresis. The deuterium isotope effect thus observed in this work provides evidence for hydrogen abstraction involved in the quenching process of singlet excited DBO by flavonoids. The data suggest the involvement of direct hydrogen atom transfer (radical scavenging) in the fluorescence quenching of DBO. Bond dissociation enthalpy calculation performed at B3LYP/6-31G(p')//B3LYP/3-21G level are in excellent agreement with the above observations and further reveal that the number OH groups and position of them decide the quenching ability of the flavonoids.

Thiol-ene and photo-cleavage chemistry for controlled presentation of biomolecules in hydrogels.

Science.gov (United States)

Grim, Joseph C; Marozas, Ian A; Anseth, Kristi S

2015-12-10

photochemical methods have led to important advances in the tissue regeneration community, namely the thiol-ene photo-click reaction for bioconjugation and photocleavage reactions that allow for the removal of protecting groups. Specific examples will be highlighted where these methodologies have been used to engineer hydrogels that control and direct cell function with the aim of inspiring their use in regenerative medicine. Copyright © 2015 Elsevier B.V. All rights reserved.

Properties of solid electrolyte interphase formed by prop-1-ene-1,3-sultone on graphite anode of Li-ion batteries

International Nuclear Information System (INIS)

Li, Bin; Xu, Mengqing; Li, Benzhen; Liu, Yanlin; Yang, Liang; Li, Weishan; Hu, Shejun

2013-01-01

Highlights: • SEI formed by PES on NG was characterized with charge/discharge test, SEM, FTIR, and XPS. • NG in PC-based electrolyte can be well protected using PES. • Sulfur-containing species is the main component of the SEI formed by PES. • Preferable reduction of PES results in the formation of protective SEI on NG. -- Abstract: The physical and chemical properties of the solid electrolyte interphase (SEI) formed by prop-1-ene-1,3-sultone (PES) on graphite anode in propylene carbonate (PC) based electrolyte for lithium ion battery were investigated by charge–discharge test, scanning electron spectroscopy with energy dispersive X-ray spectroscopy (SEM–EDS), Fourier transform infrared spectroscopy (FTIR), and X-ray photoelectron spectroscopy (XPS). It is found that the charge–discharge performance of the cell LiCoO 2 /natural graphite (NG) using PC-based electrolyte containing 3 wt% PES is superior to that containing 6 wt% propane sultone (PS), an SEI formation additive that has the similar molecular structure to PES but is reduced not as easily as PES. The results from SEM–EDS, FTIR and XPS show that the structure of graphite has been protected and some S-containing species are proven to be components of the SEI, suggesting that the preferable reduction of PES plays an important role in the formation of a protective SEI on NG

IN0523 (Urs-12-ene-3α,24β-diol) a plant based derivative of boswellic acid protect Cisplatin induced urogenital toxicity.

Science.gov (United States)

Singh, Amarinder; Arvinda, S; Singh, Surjeet; Suri, Jyotsna; Koul, Surinder; Mondhe, Dilip M; Singh, Gurdarshan; Vishwakarma, Ram

2017-03-01

The limiting factor for the use of Cisplatin in the treatment of different type of cancers is its toxicity and more specifically urogenital toxicity. Oxidative stress is a well-known phenomenon associated with Cisplatin toxicity. However, in Cisplatin treated group, abnormal animal behavior, decreased body weight, cellular and sub-cellular changes in the kidney and sperm abnormality were observed. Our investigation revealed that Cisplatin when administered in combination with a natural product derivative (Urs-12-ene-3α,24β-diol, labeled as IN0523) resulted in significant restoration of body weight and protection against the pathological alteration caused by Cisplatin to kidney and testis. Sperm count and motility were significantly restored near to normal. Cisplatin caused depletion of defense system i.e. glutathione peroxidase, catalase and superoxide dismutase, which were restored close to normal by treatment of IN0523. Reduction in excessive lipid peroxidation induced by Cisplatin was also found by treatment with IN0523. The result suggests that IN0523 is a potential candidate for ameliorating Cisplatin induced toxicity in the kidney and testes at a dose of 100mg/kg p.o. via inhibiting the oxidative stress/redox status imbalance and may be improving the efflux mechanism. Copyright © 2017 Elsevier Inc. All rights reserved.

Neokontshennaja voina Alfonsa Rebane / Ilja Nikiforov

Index Scriptorium Estoniae

Nikiforov, Ilja

1999-01-01

Vt. ka Narvskaja Gazeta 1. juuli, lk. 4. Saksa sõjaväe Eesti Julgestusgrupi 181 ülema, esimese eestlasest Rüütliristi kavaleri kolonel Alfons Rebase (1908-1976) põrm toodi kodumaale ja maeti 26. juunil Metsakalmistule

Kingipaanika, ai, ai, ai! / Mari Rebane

Index Scriptorium Estoniae

Rebane, Mari

2003-01-01

Jõulukingituseks sobilike raamatute ja heliplaatide tutvustus. Heliplaadid: Urmas Alender "Kohtumine Albertiga", Tõnu Tepandi "Kõlakoda", Pet Shop Boys "Pop Art", Erasure "Very Best Of", Depeche Mode "101", Kylie Minogue "Body Language", Korn "Take a Look in the Mirror", "Once Upon a time in Mexico"

Turismikampaania hillitses oma reklaamiklippe / Mari Rebane

Index Scriptorium Estoniae

Rebane, Mari

2005-01-01

Turismikampaaniaks valmistatud videoklippi muudeti Eestist saadud negatiivse tagasiside tõttu. Turismikampaania teostaja OÜ Brilliant Marketing Communication partner Aivar Laan selgitab videoklippide eemaldamist kampaania kodulehelt

Puitpitsvilla meenutab kunagisi hiilgeaegu / Mari Rebane

Index Scriptorium Estoniae

Rebane, Mari

2004-01-01

2003. a. Tartus väljaantud arhitektuuriraamat "Puitpitsvilla" eksponeerib Narva-Jõesuu puitvillasid. Pildid on Tartu Kõrgema Kunstikooli lõpetanud fotograafidelt Liisi Siibakult ja Aili Paadilt, saatesõna Tartu Ülikooli doktorandilt arhitektuuriajaloolaselt Epi Tohvrilt

Soodusrenoveerimine kogub hoogu / Selene-Rete Rebane

Index Scriptorium Estoniae

Rebane, Selene-Rete

2002-01-01

Tallinna kultuuriväärtuste ameti poolt koos erafirmadega käivitatud projekti "Vana maja korda" raames restaureeritakse puitmajde uksi ning väljastatkse värvipasse, mille alusel saab soodushinnaga fassaadivärve osta

Sajandi õudseimad horror-filmid / Mari Rebane

Index Scriptorium Estoniae

Rebane, Mari

2004-01-01

Meelelahutusajakirja "Entertainment Weekly" valis läheneva halloweeni puhuks välja parimad ja õudsemad õudusfilmid. Kõrgeima kunstilise tasemega õudusfilmiks tunnistati Stanley Kubricku "The Shining" (1980)

Regulation of a putative corticosteroid, 17, 21-dihydroxypregn-4-ene, 3, 20-one, in sea lamprey, Petromyzon marinus.

Science.gov (United States)

Roberts, Brent W.; Didier, Wes; Satbir, Rai; Johnson, Nicholas S.; Libants, Scot V.; Sang-Seon, Yun; Close, David

2013-01-01

In higher vertebrates, in response to stress, the hypothalamus produces corticotropin-releasing hormone (CRH), which stimulates cells in the anterior pituitary to produce adrenocorticotropic hormone (ACTH), which in turn stimulates production of either cortisol (F) or corticosterone (B) by the adrenal tissues. In lampreys, however, neither of these steroids is present. Instead, it has been proposed that the stress steroid is actually 17,21-dihydroxypregn-4-ene-3,20-dione (11-deoxycortisol; S). However, there have been no studies yet to determine its mechanism of regulation or site of production. Here we demonstrate that (1) intraperitoneal injections of lamprey-CRH increase plasma S in a dose dependent manner, (2) intraperitoneal injections of four lamprey-specific ACTH peptides at 100 lg/kg, did not induce changes in plasma S concentrations in either males or females; (3) two lamprey-specific gonadotropin-releasing hormones (GnRH I and III) and arginine-vasotocin (AVT), all at single doses, stimulated S production as well as, or to an even greater extent than CRH; (4) sea lamprey mesonephric kidneys, in vitro, converted tritiated 17a-hydroxyprogesterone (17a-P) into a steroid that had the same chromatographic properties (on HPLC and TLC) as S; (5) kidney tissues released significantly more immunoassayable S into the incubation medium than gill, liver or gonad tissues. One interpretation of these results is that the corticosteroid production of the sea lamprey, one of the oldest extant vertebrates, is regulated through multiple pathways rather than the classical HPI-axis. However, the responsiveness of this steroid to the GnRH peptides means that a reproductive rather than a stress role for this steroid cannot yet be ruled out.

[Määramised

Index Scriptorium Estoniae

2010-01-01

Ametisse määramised: Kaitseväe peainspektor (alates 18.09.2010) kolonel Jüri Järveläinen ; Meditsiiniteenistuse ülem, kaitseväe peaarst (alates 01.09.2009) kolonelleitnant Kersti Lea ; 1. jalaväebrigaadi staabiülem (alates 18.09.2010) kolonelleitnant Toomas Möls ; Kuperjanovi jalaväepataljoni ülem (alates 01.07.2010) major Maidu Allikas ; Mereväe Miinilaevade Divisjoni ülem (alates 06.08.2010) kaptenmajor Johan-Elias Seljamaa ; Lääne Kaitseringkonna ülem (alates 18.09.2010) major Margus Rebane

Ring opening of 2-aza-3-borabicyclo[2.2.0]hex-5-ene, the Dewar form of 1,2-dihydro-1,2-azaborine: stepwise versus concerted mechanisms

Directory of Open Access Journals (Sweden)

Holger F. Bettinger

2013-04-01

Full Text Available The ring opening of the Dewar form of 1,2-dihydro-1,2-azaborine, 2-aza-3-borabicyclo[2.2.0]hex-5-ene (3 is investigated by theoretical methods by using multiconfiguration SCF (CASSCF and coupled cluster theory [CCSD(T] with basis sets up to polarised quadruple-zeta quality. The title compound was previously reported to form photochemically in cryogenic noble gas matrices from 1,2-dihydro-1,2-azaborine (4. Four reaction paths for the thermal ring opening of 3 to 4 could be identified. These are the conventional disrotatory and conrotatory electrocyclic ring-opening pathways where the BN unit is only a bystander. Two more favourable paths are stepwise and involve 1,3-boron–carbon interactions. The lowest energy barrier for the isomerisation reaction, 22 kcal mol−1, should be high enough for an experimental observation in solution. However, in solution the dimerisation of 3 is computed to have a very low barrier (3 kcal mol−1, and thus 3 is expected to be a short-lived reactive intermediate.

IN0523 (Urs-12-ene-3α,24β-diol) a plant based derivative of boswellic acid protect Cisplatin induced urogenital toxicity

International Nuclear Information System (INIS)

Singh, Amarinder; Arvinda, S; Singh, Surjeet; Suri, Jyotsna; Koul, Surinder; Mondhe, Dilip M.; Singh, Gurdarshan; Vishwakarma, Ram

2017-01-01

The limiting factor for the use of Cisplatin in the treatment of different type of cancers is its toxicity and more specifically urogenital toxicity. Oxidative stress is a well-known phenomenon associated with Cisplatin toxicity. However, in Cisplatin treated group, abnormal animal behavior, decreased body weight, cellular and sub-cellular changes in the kidney and sperm abnormality were observed. Our investigation revealed that Cisplatin when administered in combination with a natural product derivative (Urs-12-ene-3α,24β-diol, labeled as IN0523) resulted in significant restoration of body weight and protection against the pathological alteration caused by Cisplatin to kidney and testis. Sperm count and motility were significantly restored near to normal. Cisplatin caused depletion of defense system i.e. glutathione peroxidase, catalase and superoxide dismutase, which were restored close to normal by treatment of IN0523. Reduction in excessive lipid peroxidation induced by Cisplatin was also found by treatment with IN0523. The result suggests that IN0523 is a potential candidate for ameliorating Cisplatin induced toxicity in the kidney and testes at a dose of 100 mg/kg p.o. via inhibiting the oxidative stress/redox status imbalance and may be improving the efflux mechanism. - Highlights: • Synthesis of a novel boswellic acid derivative (IN0523) • Counter oxidative stress induced due to Cisplatin • Protect against urogenital toxicity induced by Cisplatin

IN0523 (Urs-12-ene-3α,24β-diol) a plant based derivative of boswellic acid protect Cisplatin induced urogenital toxicity

Energy Technology Data Exchange (ETDEWEB)

Singh, Amarinder [Academy of Scientific & Innovative Research (AcSIR), New Delhi (India); PK-PD-Toxicology and Formulation Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, J& K (India); Arvinda, S [Deptt. of Pathology, Govt. Medical College, Jammu 180001, J& K (India); Singh, Surjeet [PK-PD-Toxicology and Formulation Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, J& K (India); Suri, Jyotsna [Deptt. of Pathology, Govt. Medical College, Jammu 180001, J& K (India); Koul, Surinder [Bio-Organic Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, J& K (India); Mondhe, Dilip M. [Cancer Pharmacology Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, J& K (India); Singh, Gurdarshan, E-mail: singh_gd@iiim.ac.in [PK-PD-Toxicology and Formulation Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, J& K (India); Vishwakarma, Ram [Bio-Organic Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, J& K (India)

2017-03-01

The limiting factor for the use of Cisplatin in the treatment of different type of cancers is its toxicity and more specifically urogenital toxicity. Oxidative stress is a well-known phenomenon associated with Cisplatin toxicity. However, in Cisplatin treated group, abnormal animal behavior, decreased body weight, cellular and sub-cellular changes in the kidney and sperm abnormality were observed. Our investigation revealed that Cisplatin when administered in combination with a natural product derivative (Urs-12-ene-3α,24β-diol, labeled as IN0523) resulted in significant restoration of body weight and protection against the pathological alteration caused by Cisplatin to kidney and testis. Sperm count and motility were significantly restored near to normal. Cisplatin caused depletion of defense system i.e. glutathione peroxidase, catalase and superoxide dismutase, which were restored close to normal by treatment of IN0523. Reduction in excessive lipid peroxidation induced by Cisplatin was also found by treatment with IN0523. The result suggests that IN0523 is a potential candidate for ameliorating Cisplatin induced toxicity in the kidney and testes at a dose of 100 mg/kg p.o. via inhibiting the oxidative stress/redox status imbalance and may be improving the efflux mechanism. - Highlights: • Synthesis of a novel boswellic acid derivative (IN0523) • Counter oxidative stress induced due to Cisplatin • Protect against urogenital toxicity induced by Cisplatin.

Critical Parameters and Critical-Region (p,ρ ,T) Data of trans-1,1,1,3-Tetrafluorobut-2-ene [HFO-1354mzy(E)

Science.gov (United States)

Kimura, Takeru; Kayukawa, Yohei; Miyamoto, Hiroyuki; Saito, Kiyoshi

2017-08-01

This study presents the experimental measurement of the pρ T properties and critical parameters of a low GWP type refrigerant, trans-1,1,1,3-Tetrafluorobut-2-ene (HFO-1354mzy(E)). The sample purity of the substance was 99 area %. p ρ T property measurements and visual observations of the meniscus of HFO-1354mzy(E) were carried out using a metal-bellows volumometer with an optical cell. The critical temperature was determined by observation of the critical opalescence. The critical pressure and critical density were determined as the inflection point of the isothermal p ρ T property data at the critical temperature. For more precise clarification of the thermodynamic surface in the vicinity of the critical point, additional p ρ T property measurements were carried out on three isotherms in the supercritical region. The expanded uncertainties (k = 2) in the temperature, pressure, and density measurements were estimated to be less than 3 mK, 1.2 kPa, and 0.32 \\hbox {kg} \\cdot \\hbox {m}^{-3}, respectively. The expanded uncertainties of the critical parameters were estimated to be less than 13 mK, 1.4 kPa, and 2.3 \\hbox {kg} \\cdot \\hbox {m}^{-3}, respectively. These values are the first reported for HFO-1354mzy(E) and are necessary for the development of its equation of state in the near future.

7-{[2-(4-Hydroxyphenylmethylidene]amino}-1,3-thiazol-4-yl-2-(methoxyiminoacetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-ylsulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid

Directory of Open Access Journals (Sweden)

Ghulam Fareed

2012-05-01

Full Text Available Novel 7-{[2-(4-hydroxyphenylmethylidene]amino}-1,3-thiazol-4-yl-2-(methoxyiminoacetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-ylsulfanyl]methyl}-8-oxo-5-thia-1azabicyclo [4.2.0]oct-2-ene-2-carboxylic acid was prepared by condensation of ceftriaxone disodium (1 with 4-hydroxybenzaldehyde (2 in ethanol under reflux conditions for 3–4 h. The structure of synthesized compound was elucidated using LCMS, ¹H-NMR, and CHN techniques.

N-O chemistry for antibiotics: discovery of N-alkyl-N-(pyridin-2-yl)hydroxylamine scaffolds as selective antibacterial agents using nitroso Diels-Alder and ene chemistry.

Science.gov (United States)

Wencewicz, Timothy A; Yang, Baiyuan; Rudloff, James R; Oliver, Allen G; Miller, Marvin J

2011-10-13

The discovery, syntheses, and structure-activity relationships (SAR) of a new family of heterocyclic antibacterial compounds based on N-alkyl-N-(pyridin-2-yl)hydroxylamine scaffolds are described. A structurally diverse library of ∼100 heterocyclic molecules generated from Lewis acid-mediated nucleophilic ring-opening reactions with nitroso Diels-Alder cycloadducts and nitroso ene reactions with substituted alkenes was evaluated in whole cell antibacterial assays. Compounds containing the N-alkyl-N-(pyridin-2-yl)hydroxylamine structure demonstrated selective and potent antibacterial activity against the Gram-positive bacterium Micrococcus luteus ATCC 10240 (MIC(90) = 2.0 μM or 0.41 μg/mL) and moderate activity against other Gram-positive strains including antibiotic resistant strains of Staphylococcus aureus (MRSA) and Enterococcus faecalis (VRE). A new synthetic route to the active core was developed using palladium-catalyzed Buchwald-Hartwig amination reactions of N-alkyl-O-(4-methoxybenzyl)hydroxylamines with 2-halo-pyridines that facilitated SAR studies and revealed the simplest active structural fragment. This work shows the value of using a combination of diversity-oriented synthesis (DOS) and parallel synthesis for identifying new antibacterial scaffolds.

Synthesis of Pyridine and Spiropyridine Derivatives Derived from 2-aminoprop- 1-ene-1,1,3-tricarbonitrile Together with their c-Met Kinase and Antiproliferative Evaluations.

Science.gov (United States)

Mohareb, Rafat M; Abouzied, Amr S; Abbas, Nermeen S

2018-02-07

Among a wide range of pyridines, 3-cyanopyridines acquired a special attention due to their wide range of pharmacological activities especially the therapeutic activities. Many pharmacological drugs containing the pyridine nucleus were known in the market. The aim of this work was to synthesize target molecules not only possess anti-tumor activities but also kinase inhibitors. To achieve this goal, our strategy was to synthesize a series of 3-cyanopyridine derivatives using 2-aminoprop-1-ene-1,1,3-tricarbonitrile (1) as the key starting material for many heterocyclization reactions. Muticoponent reactions were adopted using compound 1 to get different pyridine derivatives that were capable for different heterocyclization reactions. Antiproliferative evaluations and c-Met kinase, Pim-1 kinse inhibitions were perform where some compounds gave high activities. Compounds that showed high antiprolifeative activity were tested gor c-Met-independent and the results showed that compounds 5c, 5e, 5f, 7c, 7f and 16d were more active than foretinib. The Pim-1 kinase inhibition activity of some selected compounds showed that compounds 5e and 16c were high potent to inhibit Pim-1 activity. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Refractive index effects on the oscillator strength and radiative decay rate of 2,3-diazabicyclo[2.2.2]oct-2-ene.

Science.gov (United States)

Mohanty, Jyotirmayee; Nau, Werner M

2004-01-01

The photophysical properties of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) were determined in 15 solvents, two supramolecular hosts (cucurbit[7]uril and beta-cyclodextrin) as well as in the gas phase. The oscillator strength and radiative decay rate of DBO as a function of refractive index i.e. polarizability have been analyzed. The oscillator strength increases by a factor of 10 upon going from the gas phase to the most polarizable carbon disulfide, while the corresponding radiative decay rates increase by a factor of 40. There is a good empirical correlation between the oscillator strength of the weakly allowed n,pi* transition of DBO and the reciprocal bulk polarizability, which can be employed to assess the polarizability of unknown microheterogeneous environments. A satisfactory correlation between the radiative decay rate and the square of the refractive index is also found, as previously documented for chromophores with allowed transitions. However, the correlation improves significantly when the oscillator strength is included in the correlation, which demonstrates the importance of this factor in the Strickler-Berg equation for chromophores with forbidden or weakly allowed transitions, for which the oscillator strength may be strongly solvent dependent. The radiative decay rate of DBO in two supramolecular assemblies has been determined, confirming the very low polarizability inside the cucurbituril cavity, in between perfluorohexane and the gas phase. The fluorescence quantum yield of DBO in the gas phase has been remeasured (5.1 +/- 0.5%) and was found to fall one full order of magnitude below a previously reported value.

Eesti kirjandusse saabusid esimesed "blaamatud" / Mari Rebane

Index Scriptorium Estoniae

Rebane, Mari

2007-01-01

Petrone, Epp. Minu Ameerika : reportaaže ja pihtimusi 2003-2006. 1. osa. Tartu : Petrone Print, 2007 ; Petrone, Epp ; Reintam, Dagmar. Õun ära süüa? : [SL Õhtulehe populaarne suvejutt koos epiloogidega ja lisadega. Tallinn] : Pegasus, 2007 ; Reintam, Dagmar. daki.elab.siin. Tartu : Petrone Print, 2007

Tihii omut / Peeter Rebane ; interv. Aleksandra Manukjan

Index Scriptorium Estoniae

Rebane, Peeter, 1973-

2004-01-01

Uuest kohvikust ja gei-klubist "Angel" Tallinnas. Stiilse atmosfääri loomisel olid abiks stilist Gerly Tinn, graafikadisainer Rain Pikand ja reklaamifirma Division. Sisekujunduse tegi disainer John Gregg Suurbritanniast

Oskar Lutsu päevikutest / Hilve Rebane

Index Scriptorium Estoniae

Rebane, Hilve, 1938-2012

1997-01-01

Arvustus: Oskar Lutsu päevikud aastaist 1915-1916 (I) ja 1917-1919 (II). Tartu : Vanemuise Seltsi Kirjastus, 1996. (Litteraria; 7); Luts, Oskar. Viimane päevik (1944-1952). Tartu : Virgela, 1996. (Litteraria; 9)

Rhodium-catalyzed [5 + 2 + 1] cycloaddition of ene-vinylcyclopropanes and CO: reaction design, development, application in natural product synthesis, and inspiration for developing new reactions for synthesis of eight-membered carbocycles.

Science.gov (United States)

Wang, Yi; Yu, Zhi-Xiang

2015-08-18

Practical syntheses of natural products and their analogues with eight-membered carbocyclic skeletons are important for medicinal and biological investigations. However, methods and strategies to construct the eight-membered carbocycles are limited. Therefore, developing new methods to synthesize the eight-membered carbocycles is highly desired. In this Account, we describe our development of three rhodium-catalyzed cycloadditions for the construction of the eight-membered carbocycles, which have great potential in addressing the challenges in the synthesis of medium-sized ring systems. The first reaction described in this Account is our computationally designed rhodium-catalyzed two-component [5 + 2 + 1] cycloaddition of ene-vinylcyclopropanes (ene-VCPs) and CO for the diastereoselective construction of bi- and tricyclic cyclooctenones. The design of this reaction is based on the hypothesis that the C(sp(3))-C(sp(3)) reductive elimination of the eight-membered rhodacycle intermediate generated from the rhodium-catalyzed cyclopropane cleavage and alkene insertion, giving Wender's [5 + 2] cycloadduct, is not easy. Under CO atmosphere, CO insertion may occur rapidly, converting the eight-membered rhodacycle into a nine-membered rhodacycle, which then undergoes an easy C(sp(2))-C(sp(3)) reductive elimination process and furnishes the [5 + 2 + 1] product. This hypothesis was supported by our preliminary DFT studies and also served as inspiration for the development of two [7 + 1] cycloadditions: the [7 + 1] cycloaddition of buta-1,3-dienylcyclopropanes (BDCPs) and CO for the construction of cyclooctadienones, and the benzo/[7 + 1] cycloaddition of cyclopropyl-benzocyclobutenes (CP-BCBs) and CO to synthesize the benzocyclooctenones. The efficiency of these rhodium-catalyzed cycloadditions can be revealed by the application in natural product synthesis. Two eight-membered ring-containing natural products, (±)-asterisca-3(15),6-diene and (+)-asteriscanolide, have been

Occurrence of (Z)-3,4-Dideoxyglucoson-3-ene in Different Types of Beer and Malt Beer as a Result of 3-Deoxyhexosone Interconversion.

Science.gov (United States)

Hellwig, Michael; Nobis, Arndt; Witte, Sophia; Henle, Thomas

2016-04-06

In beer, 3-deoxyglucosone (3-DG) and 3-deoxygalactosone (3-DGal) are important sugar degradation products, but little is known about the relevance of the interconversion reaction between these compounds in different types of beer. In the present study, 3-DG was quantitated at concentrations of 12.9-52.7 mg/L and 3-DGal at concentrations of 6.0-26.4 mg/L in different types of beer (pilsner, wheat, bock, dark, and alcohol-free beers). The concentrations in malt beer tended to be higher. Largely overlapping concentration ranges precluded a classification of beers by their 3-deoxyglycosone contents. 3,4-Dideoxyglucoson-3-ene (3,4-DGE) was identified as an important intermediate and quantitated in beer and malt beer for the first time. The E and Z isomers of the corresponding quinoxaline were synthesized by a new synthetic approach and isolated by semipreparative HPLC. An assay was developed for quantitation of (E)- and (Z)-3,4-DGE by HPLC-MS/MS, and the Z isomer was determined at concentrations of 0.3-1.7 mg/L in beer and 0.5-4.8 mg/L in malt beer samples. The E isomer was shown to be of little importance. Concentrations of 5-hydroxymethylfurfural (HMF) were twice as high as those of (Z)-3,4-DGE in beer samples (0.4-3.7 mg/L) but much higher in malt beer samples (1.6-336 mg/L).

Photo-initiated polymerisation of 1,8-octanedithiol and styrene

International Nuclear Information System (INIS)

Ang, J.B.; Hill, D.J.T.; Pomery, P.J.; Whittaker, A.K.

1998-01-01

Full text: Photo-initiated polymerisation of the thiol-ene system has been well investigated. Its applications include adhesives, coatings and opthalmic lenses. It is unlike the usual UV curable polymeric systems which are predominantly based on acrylates. Typically, acrylate systems are not strictly stoichiometric reactions. The thiol-ene process is a reactive composition based on the stoichiometric reaction of olefins (enes, acrylates) and thiols (mercaptans), which polymerise on exposure to UV light. A unique feature of the thiol-ene system is that the reaction is not inhibited by dissolved or ambient oxygen within the system, thereby eliminating the termination reaction which occurs in acrylate systems. The mechanism of the thiol-ene reaction is a step growth addition process which propagates by a free radical chain mechanism to yield the anti-Markovnikov product scheme. The majority of thiol-ene systems investigated focus on multifunctional moieties of thiol and olefin to produce highly cross-linked networks. This discussion will focus on kinetic information obtained from a linear system comprised of a disfunctional thiol (1,8-octanedithiol) and styrene initiated by a UV light source

The traditional medicine Spilanthes acmella, and the alkylamides spilanthol and undeca-2E-ene-8,10-diynoic acid isobutylamide, demonstrate in vitro and in vivo anti-malarial activity

Science.gov (United States)

Spelman, Kevin; Depoix, Delphine; McCray, Megan; Mouray, Elisabeth; Grellier, Philippe

2010-01-01

Spilanthes spp. are used as traditional herbal medicines in Africa and India to treat malaria. Yet, to date, there is no data on active constituents or most effective extraction methods for this indication. The isolated alkylamides, spilanthol and undeca-2E-ene-8,10-diynoic acid isobutylamide, found in S. acmella Murr., were shown to have IC50s of 16.5 μg/mL and 41.4 μg/mL on Plasmodium falciparum strain PFB and IC50s of 5.8 μg/mL and 16.3 μg/mL for the chloroquine resistant P. falciparum K1 strain, respectively. Further investigations revealed that at relatively low concentrations, spilanthol and the water extract of S. acmella reduced the parasitemia 59% and 53% in mice infected with P. yoelii yoelii 17XNL at 5 mg/kg and 50 mg/kg, respectively. Unexpectedly, the 95% ethanol extract of S. acmella was less effective (36% reduction in parasitemia) at 50 mg/kg. These results provide the first evidence supporting S. acmella against malaria and demonstrating active constituents in S. acmella against P. falciparum. PMID:22692989

C60 and Sc3N@C80(TMB-PPO derivatives as constituents of singlet oxygen generating, thiol-ene polymer nanocomposites

Directory of Open Access Journals (Sweden)

Ashli R. Toles

2016-07-01

Full Text Available Numerous functionalization methods have been employed to increase the solubility, and therefore, the processability of fullerenes in composite structures, and of these radical addition reactions continue to be an important methodology. C60 and Sc3N@C80 derivatives were prepared via radical addition of the photodecomposition products from the commercial photoinitiator TMB-PPO, yielding C60(TMB-PPO5 and Sc3N@C80(TMB-PPO3 as preferred soluble derivatives obtained in high yields. Characterization of the mixture of isomers using standard techniques suggests an overall 1PPO:6TMB ratio of addends, reflecting the increased reactivity of the carbon radical. Although, a higher percentage of PPO is observed in the Sc3N@C80(TMB-PPO3 population, perhaps due to reverse electronic requirements of the substrate. Visually dispersed thiol-ene nanocomposites with low extractables were prepared using two monomer compositions (PETMP:TTT and TMPMP:TMPDE with increasing fullerene derivative loading to probe network structure-property relationships. Thermal stability of the derivatives and the resulting networks decreased with increased functionality and at high fullerene loadings, respectively. TMPMP:TMPDE composite networks show well-dispersed derivatives via TEM imaging, and increasing Tg’s with fullerene loading, as expected for the incorporation of a more rigid network component. PETMP:TTT composites show phase separation in TEM, which is supported by the observed Tg’s. Singlet oxygen generation of the derivatives decreases with increased functionality; however, this is compensated for by the tremendous increase in solubility in organic solvents and miscibility with monomers. Most importantly, singlet oxygen generation from the composites increased with fullerene derivative loading, with good photostability of the networks.

Spectral behavior and photophysical parameters of (2Z)-3-[4-(dimethylamino) phenyl]-2-(4-fluorophenyl) prop-2-ene-nitrile (DPF) in different media

Energy Technology Data Exchange (ETDEWEB)

Pannipara, Mehboobali [Department of Chemistry, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589 (Saudi Arabia); Asiri, Abdullah M. [Department of Chemistry, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589 (Saudi Arabia); Center of Excellence for Advanced Materials Research, King Abdulaziz University, Jeddah 21589, P.O. Box 80203 (Saudi Arabia); Alamry, Khalid A. [Department of Chemistry, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589 (Saudi Arabia); Salem, Ibrahim A. [Department of Chemistry, Faculty of Science, Tanta University, 31527 Tanta (Egypt); El-Daly, Samy A., E-mail: samyeldaly@yahoo.com [Department of Chemistry, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589 (Saudi Arabia); Department of Chemistry, Faculty of Science, Tanta University, 31527 Tanta (Egypt)

2015-01-15

A new fluorophore, (2Z)-3-[4-(dimethylamino) phenyl]-2-(4-fluorophenyl) prop-2-ene-nitrile (DPF), was synthesized by knoevenagel condensation of 4-(dimethylamino) benzaldehyde and 4-fluorobenzyl cyanide in ethanol using NaOH as base. The electronic absorption and emission characteristic of DPF were studied in different solvents. The X-ray crystallographic structure of DPF was also investigated. DPF exhibits a red-shift in its emission spectrum as solvent polarity increases, indicating a large change in the dipole moment of dye molecule upon excitation due to intramolecular charge transfer in excited DPF{sup ⁎}. The fluorescence quantum yield depends strongly on the properties of the solvents, which was attributed to positive and negative solvatokinetic effects. A crystalline solid of DPF gives a strong yellow emission at about 532 nm; these phenomena are important for the application of DPF dye in organic photoemitting diode. The photochemical quantum yield of cis–trans isomerization of DPF was also determined in different solvents. The DPF dye displays solubilization in both cationic (CTAB) and anionic (SDS) micelle and may be used as a probe to determine the critical micelle concentration (CMC) of SDS and CTAB. - Highlights: • Organic pi conjugated molecule with a donor acceptor group was studied. • Crystalline solid of the molecule shows strong and intense yellow emission. • The dye displays solubilization in cationic micelle with abrupt change in emission intensity at CMC. • This work gives an insight into the application of organic luminescent material in various fields.

Extra-nodal extension is a significant prognostic factor in lymph node positive breast cancer.

Directory of Open Access Journals (Sweden)

Sura Aziz

Full Text Available Presence of lymph node (LN metastasis is a strong prognostic factor in breast cancer, whereas the importance of extra-nodal extension and other nodal tumor features have not yet been fully recognized. Here, we examined microscopic features of lymph node metastases and their prognostic value in a population-based cohort of node positive breast cancer (n = 218, as part of the prospective Norwegian Breast Cancer Screening Program NBCSP (1996-2009. Sections were reviewed for the largest metastatic tumor diameter (TD-MET, nodal afferent and efferent vascular invasion (AVI and EVI, extra-nodal extension (ENE, number of ENE foci, as well as circumferential (CD-ENE and perpendicular (PD-ENE diameter of extra-nodal growth. Number of positive lymph nodes, EVI, and PD-ENE were significantly increased with larger primary tumor (PT diameter. Univariate survival analysis showed that several features of nodal metastases were associated with disease-free (DFS or breast cancer specific survival (BCSS. Multivariate analysis demonstrated an independent prognostic value of PD-ENE (with 3 mm as cut-off value in predicting DFS and BCSS, along with number of positive nodes and histologic grade of the primary tumor (for DFS: P = 0.01, P = 0.02, P = 0.01, respectively; for BCSS: P = 0.02, P = 0.008, P = 0.02, respectively. To conclude, the extent of ENE by its perpendicular diameter was independently prognostic and should be considered in line with nodal tumor burden in treatment decisions of node positive breast cancer.

Synthesis and Evaluation of in Vitro Biological Activity of 4-Substituted Arylpiperazine Derivatives of 1,7,8,9-Tetrachloro-10,10-dimethoxy-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione

Directory of Open Access Journals (Sweden)

David Collu

2009-12-01

Full Text Available A series of twenty arylpiperazine derivatives of 1,7,8,9-tetrachloro-10,10-dimethoxy-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione have been prepared. These derivatives were tested in vitro with the aim of identifying novel lead compounds active against emergent and re-emergent human and cattle infectious diseases (AIDS, hepatitis B and C, tuberculosis, bovine viral diarrhea. In particular, these compounds were evaluated in vitro against representatives of different virus classes, such as a HIV-1 (Retrovirus, a HBV (Hepadnavirus and the single-stranded RNA+ viruses Yellow fever virus (YFV and Bovine viral diarrhea virus (BVDV, both belonging to the Flaviridae. Compounds 2c, 2g and 3d showed a modest activity against CVB-2. The molecular structures of the starting imide 1 and one of propyl-piperazine derivatives, 3b, have been determined by an X-ray crystallography study.

Zinc(II PVC-based membrane sensor based on 5,6-benzo-4,7,13,16,21,24- hexaoxa-1,10-diazabicyclo[8,8,8]hexacos-5-ene

Directory of Open Access Journals (Sweden)

Zamani Hassan Ali

2006-01-01

Full Text Available The 5,6-benzo-4,7,13,16,21,24-hexaoxa-1,10-diazabicyclo[8,8,8]hexacos-5-ene (BHDE was used as an excellent ionophore in construction of a Zn(II PVC-based membrane sensor. The best performance was obtained with a membrane composition of 30% poly(vinyl chloride, 64.5% nitrobenzen (NB, 2.5% BHDE and 3% sodium tetraphenylborate (NaTPB. This sensor shows very good selectivity and sensitivity towards zinc ion over a wide variety of cations, including alkali, alkaline earth, transition and heavy metal ions. The sensor revealed a great enhancement in selectivity coefficients for zinc ions, in comparison to the previously reported zinc sensors. The proposed sensor exhibits a Nernstian behavior (with slope of 29.1 ? 0.4 mV per decade over a wide concentration range (1.0 10-6-1.0 10-1 mol L-1 with a detection limit of 6.3 x10-7 mol L-1 (41.2 ng mL-1. It shows relatively fast response time, in the whole concentration range (< 10s, and can be used for at least 10 weeks in a pH range of 2.8-7.3. The proposed sensor was successfully used in direct determination of zinc ions in wastewater of industrial zinc electroplating companies, and also as an indicator electrode in titration with EDTA.

Krest Alfonsa Rebane / Toomas Virkus ; interv. Maksim Rogalski

Index Scriptorium Estoniae

Virkus, Toomas

1999-01-01

Saksa sõjaväe Eesti Julgestusgrupi 181 ülema, esimese eestlasest Rüütliristi kavaleri kolonel Alfons Rebase (1908-1976) põrm tuuakse kodumaale ja maetakse 26. juunil Metsakalmistule. Intervjuu A. Rebase ristipoja Toomas Virkusega

Michael Moore kaevati kohtusse pettuse eest / Mari Rebane

Index Scriptorium Estoniae

Rebane, Mari

2006-01-01

Dokumentaalfilm "9/11 Fahrenheiti" ("Fahrenheit 9/11") : režissöör Michael Moore : USA 2004. Iraagi sõja invaliidistunud veteran andis režissööri kohtusse teda kujutavate flmikaadrite loata ja tenentsliku kasutamise pärast

Aasta Betoonehitis 2003 - elamu mere kaldal / Enno Rebane

Index Scriptorium Estoniae

Rebane, Enno, 1964-

2004-01-01

2003. a. parim betoonehitis - arhitekt Emil Urbeli kavandatud eramu (projekteerija TA Konsult OÜ, betoonitööde teostaja Mapri Projekt OÜ). Eriauhinna arhitektuurse lahenduse eest sai Siiri Vallneri, Hanno Grossschmidti ja Tomomi Hayashi kavandatud Lasnamäe spordihoone (projekteerija TA Konsult OÜ, ehitasid Eesti Ehitus OÜ, AS E-Betoonelement - ka betoonisegu tarnija) ja betoonitehnoloogia eest AS E-Betoonelement Ekseko seafarmi sõnnikuhoidla eest Viljandimaal. IV betoonipäevast

Tallinnas möllas 2208 tantsijat / Eveli Rebane

Index Scriptorium Estoniae

Rebane, Eveli

2007-01-01

Kalevi spordihallis 14.-15. aprillil toimunud rahvusvahelised tantsuvõistlused "Estonian Open Cup" ja "Baltic Cup". Võistlusi korraldab IDO (International Dance Organisation) Eesti haru. "Baltic Cupi" võitjaks tuli Kuressaare tantsutrupp Semiir

Huvi või sundus - meie valik / Rein Rebane

Index Scriptorium Estoniae

Rebane, Rein

2011-01-01

Eesti õpilaste tulemused rahvusvaheliste PISA ja TIMSS-i testide põhjal on olnud head. Samadest uuringutest on aga selgunud, et nii Eesti õpilaste kui ka õpetajate rahulolu kooliga on üks madalamaid maailmas

Narnia lood pakuvad naudingut just lastele / Mari Rebane

Index Scriptorium Estoniae

Rebane, Mari

2005-01-01

Walden Media tootis koos Walt Disney Pictures'iga ekraniseeringu C.S. Lewise 1950.a. ilmunud romaanist "Narnia lood : Lõvi, nõid ja riidekapp" (Chronicles of Narnia : The Lion, the Witch and the Wardrobe")

Rakvere Teater alustab veebruaris uue projektiga / Triin Rebane

Index Scriptorium Estoniae

Rebane, Triin

2010-01-01

Teatriprojektist "Rakvere Teater esitleb", mille raames jõuavad kord kuus lavale kaasaegse teatri tavapäratumad lavastused, sarja idee autor on teatrijuht Joonas Tartu. 1. veebruaril Alissa Šnaideri, Päär Pärensoni, Renzo van Steenbergeni "Tavaj"

New generation in Estonian animation / Mari-Liis Rebane

Index Scriptorium Estoniae

Rebane, Mari-Liis, 1988-

2010-01-01

Eesti animafilmide loojate uuest põlvkonnast, animafilmide tegemise võimalustest, uute animafilmide tasemest. Martinus Daane Klemeti animafilmidest "Furry Flurry" (2006) ja "Light My Fire" (2007) ning joonisfilmist "Õhus" (Eesti Joonisfilm, 2009, kunstnik Gerda Märtens)

Plaadid / Mari Rebane, Heidi Purga, Tiiu Laks...[jt.

Index Scriptorium Estoniae

2008-01-01

Uutest heliplaatidest Sigur Ros "Heim/Hvart", Jay-Z "American Gangster", Bob Marley and The Wailers "Roots, Rock, Remixed", Ghostface killah "The Big doe Rehab", Backstreet Boys "Unbreakable", Matchbox Twenty "Exile on Mainstream", "Just" Hits 6"

Eesti Päevaleht korjas kolm pressipreemiat / Mari Rebane

Index Scriptorium Estoniae

Rebane, Mari

2006-01-01

Eile jagas Eesti Ajalehtede Liit 2005. aasta ajakirjandussaavutuste eest preemiaid. Eesti Päevaleht sai kujundusauhinna esikaane ja uudiskülgede eest ning arvamusloo preemia. Esikülje kujundusauhinna sai "Eesti Päevalehe" peakunstnik Merike Pinn. Parimateks uudisfoto autoriteks tunnistati Andras Kralla "Äripäevast" ja Margus Ansu "Tartu Postimehest", parimateks olemusfoto autoriteks Raul Mee "Äripäevast" ja Sille Annuk "Tartu Postimehest"

Tehases Polymer valmistatakse kummilelude asemel kultuuri / Mari Rebane

Index Scriptorium Estoniae

Rebane, Mari

2005-01-01

Tallinna Kristiine linnaosas tegutsevast loovinimeste koondumispaigast kultuuritehasest Polymer. Kultuuritehases töötavad maalikunstnik Alice Kask, skulptor Neeme Külm, teatrikunstnik Mae Kivilo, filmikunstnik Mare Raidma. Vaata ka www.kultuuritehas.ee

Suve kauge trummipõrin kutsub festivalidele / Mari Rebane

Index Scriptorium Estoniae

Rebane, Mari

2004-01-01

Euroopas suvel toimuvatest popmuusika festivalidest Provinssirock, Pori Jazz Festival, Midtfyns Rockfestival, Roskilde Festival, Glastonbury Festival, V Festivals, Rock Am Ring, Pepsi Sziget. Olulisematest festivalidest Eestis

New optically active and thermally stable poly(amide-imide)s containing N,N'-(Bicyclo[2,2,2]oct-7-ene-2,3,5,6-tetracarboxylic)-bis-L-alanine and aromatic diamines: synthesis and characterization

International Nuclear Information System (INIS)

Faghihi, Khalil; Absalar, Morteza; Hajibeygi, Mohsen

2009-01-01

Five new optically active poly(amide-imide)s (PAIs) 6a-e were prepared by direct polycondensation reaction of the newly synthesized N,N'-(bicyclo[2,2,2]oct-7-ene-2,3,5,6-tetra carboxylic)-bis-L-alanine 4 with various aromatic diamines 5a-e using polar aprotic solvents such as N-methyl-2-pyrrolidone (NMP). In this technique triphenyl phosphite (TPP) and pyridine were used as condensing agents to form poly(amide-imide)s through the N-phosphonium salts of pyridine. All of the polymers were obtained in quantitative yields with inherent viscosities between 0.29-0.46 dL g -1 and were highly soluble in polar aprotic solvents such as N,N-dimethyl acetamide (DMAc), N,N-dimethyl formamide (DMF), dimethyl sulfoxide (DMSO), N-methyl- 2-pyrrolidone (NMP) and solvents such as sulfuric acid. They were fully characterized by means of 1 H NMR, FTIR spectroscopy, elemental analyses, inherent viscosity, solubility test, specific rotation and thermal properties of these polymers were investigated using thermogravimetric analysis techniques (TGA and DTG). (author)

Riigi teaduspreemiate 2003 kandidaadid / Villi Ehatamm

Index Scriptorium Estoniae

Ehatamm, Villi

2003-01-01

2003. a. teaduspreemia kandidaadid: J. Einasto, A.-E. Kaasik, R. Hagelberg, H. Rätsep, R. Pullat, M. Kilp, V. Laan, P. Normak, S. Keevallik, V. Hižnjakov, M. Selg, T. Pehk, T. Rang, M. Mihkla, A. Eek, E. Meister, H.-J. Kaalep, J. Harro, A. Metspalu, T. Jürimäe, J. Haberman, A. Miidel, T. Nõges, E. Pihu, A. Raukas, R. Gross, T. Paaver, A. Valdmann, Ü. Tamm, M. Mandre, K. Ots, H. Pärn, J. Klõseiko, T. Rajasalu, V. Vensel, E. Berg, J. Reiljan, U. Varblane, K. Katus, A. Puur, A. Põldma, K. Rebane, M. Hallik, M. Must, A. Univere, E. Juhkam, I. Käsi, V. Lonn, E. Niit, K. Kirme

New labdane diterpenes from Solidago canadensis.

Science.gov (United States)

Wangensteen, Helle; Phan, Thi T; Rise, Frode; Halvorsen, Trine G; Malterud, Karl E

2012-01-01

The ethanol extract of roots of Solidago canadensis yielded eight labdane-type diterpenes. Five of those were new natural compounds (9,13,15,16-bisepoxy-labdane-7-ene-6,15-dione (3a), 13-epi-9,13,15,16-bisepoxy-labdane-7-ene-6,15-dione (3b), 15,16-epoxy-labdane-7,13-diene-6,16-dione (5), 15-ethoxy-9,13,15,16-bisepoxy-labdane-7-ene-6-one (6a) and 13-epi-15-ethoxy-9,13,15,16-bisepoxy-labdane-7-ene-6-one (6b). The known labdane diterpenes deoxysolidagenone (1), solidagenone (2) and 15,16-epoxy-labdane-7,13-diene-6,15-dione (4) were also isolated. Chemical structures were determined using 1D and 2D NMR techniques and MS analysis.

Design of peptide substrates for nanosecond time-resolved fluorescence assays of proteases: 2,3-diazabicyclo[2.2.2]oct-2-ene as a noninvasive fluorophore.

Science.gov (United States)

Hennig, Andreas; Florea, Mara; Roth, Doris; Enderle, Thilo; Nau, Werner M

2007-01-15

Fluorescence protease assays were investigated with peptide substrates containing a 2,3-diazabicyclo[2.2.2]oct-2-ene-labeled asparagine (Dbo) as a fluorescent amino acid. The special characteristic of the fluorophore Dbo is its exceedingly long fluorescence lifetime (ca. 300 ns in water under air), which allows the use of nanosecond time-resolved fluorescence (Nano-TRF) detection to efficiently suppress shorter-lived background emission. In addition, the natural amino acids tryptophan and tyrosine can be employed as intramolecular fluorescence quenchers, which facilitates substrate design. Fourteen synthetic peptide substrates (composed of 2-19 amino acids) and five enzymes (trypsin, pepsin, carboxypeptidase A, leucine aminopeptidase, and chymotrypsin) were investigated and, in all 28 examined combinations, enzymatic activity was detected by monitoring the increase in steady state fluorescence with time and determining the reaction rates as kcat/Km values, which ranged from 0.2 to 80x10(6) M-1 min-1. The results suggest an excellent compatibility of the very small and hydrophilic fluorescent probe Dbo with solid-phase peptide synthesis and the investigated proteases. For all 14 peptides the fluorescence lifetimes before and after enzymatic cleavage were measured and Nano-TRF measurements were performed in 384-well microplates. The fluorescence lifetimes of the different peptides provide the basis for the rational design of Dbo-based fluorescent substrates for protease assays. Measurements in Nano-TRF mode revealed, in addition to efficient suppression of background fluorescence, an increased differentiation between cleaved and uncleaved substrate. The Dbo-based assays can be adapted for high-throughput screening.

New optically active and thermally stable poly(amide-imide)s containing N,N'-(Bicyclo[2,2,2]oct-7-ene-2,3,5,6-tetracarboxylic)-bis-L-alanine and aromatic diamines: synthesis and characterization

Energy Technology Data Exchange (ETDEWEB)

Faghihi, Khalil; Absalar, Morteza; Hajibeygi, Mohsen [Arak University (Iran, Islamic Republic of). Faculty of Science. Organic Polymer Chemistry Research Lab.

2009-07-01

Five new optically active poly(amide-imide)s (PAIs) 6a-e were prepared by direct polycondensation reaction of the newly synthesized N,N'-(bicyclo[2,2,2]oct-7-ene-2,3,5,6-tetra carboxylic)-bis-L-alanine 4 with various aromatic diamines 5a-e using polar aprotic solvents such as N-methyl-2-pyrrolidone (NMP). In this technique triphenyl phosphite (TPP) and pyridine were used as condensing agents to form poly(amide-imide)s through the N-phosphonium salts of pyridine. All of the polymers were obtained in quantitative yields with inherent viscosities between 0.29-0.46 dL g{sup -1} and were highly soluble in polar aprotic solvents such as N,N-dimethyl acetamide (DMAc), N,N-dimethyl formamide (DMF), dimethyl sulfoxide (DMSO), N-methyl- 2-pyrrolidone (NMP) and solvents such as sulfuric acid. They were fully characterized by means of {sup 1}H NMR, FTIR spectroscopy, elemental analyses, inherent viscosity, solubility test, specific rotation and thermal properties of these polymers were investigated using thermogravimetric analysis techniques (TGA and DTG). (author)

Whats 'App-ening'

DEFF Research Database (Denmark)

Ankersen, Dorit V; Weimers, Petra; Burisch, Johan

2017-01-01

in number. ehealth helps patients in coping with their disease by promoting self-management, which increases adherence to medical treatment and diets, and leads to an improved quality of life. For irritable bowel syndrome (IBS), there are multiple applications that provide dietary advice, for example, a low...

Repliik / Ene Pajula

Index Scriptorium Estoniae

Pajula, Ene, 1950-

2008-01-01

Õpilaskodude foorumist ja õpilaskodudest, mis on loodud kodanikualgatuse korras ja nende inimeste tunnustamise vajadusest, tänu kellele meil on kakskümmend kaheksa õpilaskodu, kus elule tagasi võidetud saab nii mõnigi laps

Ene-ene-yne Reactions: Activation Strain Analysis and Role of Aromaticity

NARCIS (Netherlands)

Fernandez, I.; Bickelhaupt, F.M.; Cossío, F.P.

2014-01-01

The trend in reactivity of the thermal cycloisomerization reactions of 1,3-hexadien-5-ynes, A=B-C=D-E≡F, were explored and analyzed by using density functional theory at the M06-2X/def2-TZVPP level. These reactions proceed through formally aromatic transition states to form a bent-allene

Inert Reassessment Document for Poly(oxyethylene) adducts of mixed phytosterols

Science.gov (United States)

Poly(oxyethy1ene) adducts of mixed phytosterols is uncategorized as to list classification status. Based upon the reasonable certainty of no harm safety finding, the List 4B classification for poly(oxyethy1ene) adducts of mixed phytosterols is affirmed.

Kuressaarest kaks laureaaditiitlit / Riina Mägi

Index Scriptorium Estoniae

Mägi, Riina, 1957-

2008-01-01

Maakondlikust etlejate konkursist. Žüriisse kuulusid Maret Oomer, Asta Leiten ja Kalle Piiskoppel. 5.-7. klasside arvestuses I koht: Marleen Petersell. Äramärkimist leidsid: Kristian Käresk, Maarja-Liis Mölder ja Anita Tuula. 7.-9. klasside arvestuses I koht: Oliver Taul. Esile tõsteti: Rauno Reinas, Riko Osila, Linda Maisväli ja Piia Puuraid. 10.-12. klasside arvestuses I koht: Karl Sakrits. Ära märgiti: Elin Küti, Virgo Ernits, Maria Orb. Kommenteerisid Asta Leiten, Liann Saage-Vahur. Ka Kuressaares toimunud vabariiklikust etlejate konkursist, kommentaare jagasid Merle Rekaya, Rita Ilves. Zhürisse kuulusid Aare Toikka, Tiina Rebane, Hans Kaldoja, Kristiina Omer ja Keete Viira. Peapreemia nooremas vanuseastmes Markkus Pulgale, keskmises vanuseastmes Anna Talvile ja vanemas vanuseastmes Doris Täkkerile.

GC-MS study of Nigella sativa (seeds fatty oil

Directory of Open Access Journals (Sweden)

Mehta, B. K.

2002-06-01

Full Text Available The GC-MS study of N. sativa (seeds fatty oil revealed the presence of 26 compounds which were identified as methyl hept-6-enoate,1-phenylhepta-2,4-dione, pentadecane, hexadec-1-ene, 1-phenyldecan-2-one, octadec-1-ene, octadecane, methyl pentadecanoate, bis(3-chlorophenyl ketone, diethyl phthalate, ethyl octadec-7-enoate, methyl octadecanoate, tricos-9-ene, octadeca-9,12-dienoic acid, hexadecanoic acid, methyl hexadecanoate, methyl octadec-15-enoate, henicosan-10-one, 2-methyl octadecanoic acid, docos-1-ene, ethyl octadecanoate, methyl octadecanoate, pentacos-5-ene,12-methyltricosane, dibutyl phthalate and 2-methyltetracosane.El estudio por GC-MS del aceite de la semilla de Nigella sativa reveló la presencia de 26 compuestos los cuales fueron identificados como: hept-6-enoato de metilo, 1-fenilhepta-2,4-diona, pentadecano, hexadec-1-eno, 1-fenildecan-2-ona, octadec-1-eno, octadecano, pentadecanoato de metilo, bis(3-clorofenil cetona, ftalato de dietilo, octadec-7-enoato de etilo, octadecanoato de metilo, tricos-9-eno, ácido octadeca-9,12-dienoico, ácido hexadecanoico, hexadecanoato de metilo, octadec-15-enoato de metilo, henicosan-10-ona, ácido 2-metil octadecanoico, docos-1-eno, octadecanoato de etilo, octadecanoato de metilo, pentacos-5-eno, 12-metiltricosano, ftalato de dibutilo y 2-metiltetracosano.

Direct Aminolysis of Ethoxycarbonylmethyl 1,4-Dihydropyridine-3-carboxylates

Directory of Open Access Journals (Sweden)

Brigita Vigante

2015-11-01

Full Text Available The ethoxycarbonylmethyl esters of 1,4-dihydropyridines were directly converted into carbamoylmethyl esters in the presence of 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD in good to excellent yields under mild conditions. The use of TBD is crucial for the successful aminolysis of ethoxycarbonylmethyl ester of 1,4-dihydropyridines with secondary amines as without it the reaction does not proceed at all. The aminolysis reaction proceeded regioselectively, as the alkyl ester conjugated with the 1,4-dihydropyridine cycle was not involved in the reaction. Screening of other N-containing bases, such as triethylamine (TEA, pyridine, 4-(N,N-dimethylaminopyridine (DMAP, 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU, 1,5-diazabicyclo[4.3.0]non-5-ene (DBN, imidazole, tetramethyl guanidine (TMG and 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene (MTBD as catalysts revealed no activity in the studied reaction.

Simpsonite film alustas võimsalt / Mari Rebane, Mart Niineste

Index Scriptorium Estoniae

Rebane, Mari

2007-01-01

Matt Groeningi loodud tegelaskujudega täispikk animafilm "Simpsonite film" ("The Simpsons Movie") : režissöör David Silverman : Ameerika Ühendriigid 2007. Eestis käis avanädalavahetusel seda vaatamas 13 698 inimest

Eesti Raudtee kasvatab läbilaskevõimet / Kirti Rebane

Index Scriptorium Estoniae

Rebane, Kirti

2005-01-01

Eesti Raudtee investeeringutest, kasumist, kaubaveo mahtudest, majandusnäitajatest, mis annavad head eeldused börsileminekuks, mille üheks plussiks oleks ettevõtte avatumaks muutumine. Tabelid: Eesti Raudtee rahavood (mln kr); Majandusnäitajad. Diagrammid: Eesti Raudtee investeeringud (mln kr); Eesti Raudtee töötajate arv

Kas "Hirmu faktor" paneb võistleja surmaohtu? / Selene Rebane

Index Scriptorium Estoniae

Rebane, Selene

2004-01-01

Rahvusvaheline teleprojekt, mille võtted toimuvad Lõuna-Aafrikas. Eesti ainus kaskadöör Enar Tarmo hindab USAs tehtud seriaali pealtnäha kõige eluohtlikumaid trikke turvalisuse seisukohalt. Lisaks tutvustus "Tõsieluseriaal "Hirmu faktor""

Foorumteater pakub võimalust teisiti mõelda / Mari Rebane

Index Scriptorium Estoniae

Rebane, Mari

2005-01-01

VAT Teatri foorumgrupp ja MTÜ Caritas loovuskooli teatriringi noored etendavad Sõle gümnaasiumis üht osa VAT Teatri foorumgrupi koolivägivalla ennetamise projektist "ValikuVabadus" (projektijuht M.-L. Velberg), mis hõlmab kuut Tallinna kooli. Ka lühidalt foorumteatri ajaloost

Uus raamat tõstis Potteri-palaviku haripunkti / Mari Rebane

Index Scriptorium Estoniae

Rebane, Mari

2007-01-01

Eestis esilinastus 20. juulil Harry Potteri viies film "Harry Potter ja Fööniksi ordu" ("Harry Potter and the Order of the Phoenix"), režissöör David Yates : Ameerika Ühendriigid-Suurbritannia 2007. Alates 21. juulist saab osta seitsmendat ja ühtlasi viimast J. K. Rowlingu Potteri-sarja raamatut "Harry Potter and the Deathly Hallows"

Kontserdisari kutsub "Klavessiinisalongi"

Index Scriptorium Estoniae

2008-01-01

Rakvere Kaurikooli saalis toimuvatest kontsertidest: 7. dets."iViva Espagna!" (esinevad klavessiiniduo Ene Nael - Kristiina Are ja näitleja Tarmo Song), 15. veebr. "Häälemeelne" (laulja Kelli Pärnaste ja kitarrist Tiit Korsar, klavessinist Ene Nael) ja 26. apr. "Fiori musicali" (Tallinna Vanalinna Hariduskolleegiumi, Tallinna Muusikakeskkooli ja Rakvere Kaurikooli klavessiiniõpilased)

Nasha "Russkaja galereja" v Madride

Index Scriptorium Estoniae

2005-01-01

Kaasaegse kunsti laat ARCO Madridis. Osaleb "Vene galerii" Tallinnast näitusega TRINITY. Galerist Masha Melnikova. Osalevad Ene-Liis Semper ja Moskva kunstnikud Anton Litvin ning Bogdan Mamonov. Ene-Liis Semper näitab videokunsti, Anton Litvin fotoprojekti ja Bogdan Mamonov realistlikke portreid. Näitus märtsis Vene saatkonna galeriis Tallinnas

Chemical constituents from Aspidosperma illustre (Apocynaceae)

International Nuclear Information System (INIS)

Barbosa, Lara F.; Mathias, Leda; Braz-Filho, Raimundo; Vieira, Ivo J. Curcino

2010-01-01

A new natural product oleanane-type triterpene, olean-12-ene-11α-methoxy-3β-acetate (10) was isolated from Aspidosperma illustre, together with β-amyrin (3), lupeol (4), β-amyrin acetate (5), lupeol acetate (6), olean-12-ene-28-hydroxy-3α-tetradecanoate (7), olean-12-ene-28-carboxy-3α-hexadecanoate (8), ursolic acid (9) triterpenes, and two monoterpenic indole alkaloids, b-yoimbine (1) and 1,2-dehydroaspidospermidine (2). These compounds were characterized on their spectral data basis, mainly one- ( 1 H, 13 C, APT) and two-dimensional ( 1 H- 1 H-COSY, 1 H- 1 HNOESY, HMQC and HMBC) NMR, and mass spectra, involving also comparison with data from the literature. (author)

Three new triterpene esters from pumpkin (Cucurbita maxima) seeds.

Science.gov (United States)

Kikuchi, Takashi; Ueda, Shinsuke; Kanazawa, Jokaku; Naoe, Hiroki; Yamada, Takeshi; Tanaka, Reiko

2014-04-16

Three new multiflorane-type triterpene esters, i.e. 7α-hydroxymultiflor-8-ene-3α,29-diol 3-acetate-29-benzoate (1), 7α-methoxymultiflor-8-ene-3α,29-diol 3,29-dibenzoate (2), and 7β-methoxymultiflor-8-ene-3α,29-diol 3,29-dibenzoate (3), were isolated from seeds of Cucurbita maxima, along with the known compound, multiflora-7,9(11)-diene-3α,29-diol 3,29-dibenzoate (4). Compound 1 exhibited melanogenesis inhibitory activities comparable with those of arbutin. In cytotoxicity assays, compounds 1 and 3 exhibited weak cytotoxicity, with IC50 values of 34.5-93.7 μM against HL-60 and P388 cells.

Three New Triterpene Esters from Pumpkin (Cucurbita maxima Seeds

Directory of Open Access Journals (Sweden)

Takashi Kikuchi

2014-04-01

Full Text Available Three new multiflorane-type triterpene esters, i.e. 7α-hydroxymultiflor-8-ene-3α,29-diol 3-acetate-29-benzoate (1, 7α-methoxymultiflor-8-ene-3α,29-diol 3,29-dibenzoate (2, and 7β-methoxymultiflor-8-ene-3α,29-diol 3,29-dibenzoate (3, were isolated from seeds of Cucurbita maxima, along with the known compound, multiflora-7,9(11-diene-3α,29-diol 3,29-dibenzoate (4. Compound 1 exhibited melanogenesis inhibitory activities comparable with those of arbutin. In cytotoxicity assays, compounds 1 and 3 exhibited weak cytotoxicity, with IC50 values of 34.5–93.7 μM against HL-60 and P388 cells.

Taevo Gans / Ene Ammer

Index Scriptorium Estoniae

Ammer, Ene

1998-01-01

Sisearhitekt Taevo Gansist. Tudengipõlvest, selle aja projektidest, sõpruskonnast, tandemist Summatavet & Gans, Venemaa tellimustest, kaastöölistest. Üksinda Hommilkumaal vene tarbekunsti näitusega 1974. a. 1988. a. loodud perefirmast "GaDis" (omanikud Taevo, Helle Gans, Riia Oja), mis nõustab ka "Wermot" mööbli osas. "GaDise" sisekujundusprojektidest, millega Taevo ja Helle Gans tegelevad üheskoos

Grunge kodukujunduses / Ene Vool

Index Scriptorium Estoniae

Vool, Ene, 1948-

2004-01-01

Low-tech, campi ja grunge ehitus- ja sisustusstiilidest meil ja mujal - kommenteerivad Andro Kööp ja Ain Nurmela. Tutvustatakse ka Mari-Mira projekti Pariisis, mis kujutab endast nn. mutant-küla, putka- ja onnikultuuri koketeriid. Artikli lõpus kommenteerib kunstiteadlane Karin Paulus grungestiili muusikas, riietuses ja sisekujunduses.

LEADER-tegevusest / Ene Sarapuu

Index Scriptorium Estoniae

Sarapuu, Ene

2009-01-01

Läänemaa LEADER-tegevusgrupi eesmärk on maakonna kui terviku ühtne areng, et kogu Läänemaa oleks vajalike teenustega kaetud ning ettevõtjad julgeks ning suudaks uute teenuste ja toodetega turule tulla

Chemical Constituents from Bombacopsis glabra (Pasq. A. Robyns: Complete 1H and 13C NMR Assignments and X Ray Structure of 5-Hydroxy-3,6,7,8,4'-pentamethoxyflavone

Directory of Open Access Journals (Sweden)

Paula Vanderlúcia F.

2002-01-01

Full Text Available The flavone 5-hydroxy-3,6,7,8,4'-pentamethoxyflavone (1 and the triterpenes lupenone, 9,19-cyclolanost-23-ene-3beta,25-diol (2, (24R-9,19-cyclolanost-25-ene-3beta,24-diol (3 and (24S-9,19-cyclolanost-25-ene-3beta,24-diol (4 were isolated from the hexane extract of the stem bark of Bombacopsis glabra (Bombacaceae. The structures were determined by 13C and ¹H NMR (1D and 2D and mass spectrometry, and by comparison with literature data for triterpenes. The structure of the flavone 1 was unambiguously confirmed by a X-ray diffraction study. The five substances were isolated for the first time from Bombacaceae species.

Situación de riesgo y salud de los adolescentes en el valle de los ríos Apurímac, Ene y Mantaro en Perú

Directory of Open Access Journals (Sweden)

Fabiola Yeckting Vilela

Full Text Available Se presenta el diagnóstico de las condiciones de vida de los adolescentes varones y mujeres en la zona del valle de los ríos Apurímac, Ene y Mantaro (VRAEM, quienes atraviesan situaciones de riesgo y vulnerabilidad social y sexual debido a los altos niveles de producción de la hoja de coca y el contexto del narcotráfico, que crean la ilusión del rápido ascenso social. A partir de ello, es necesario preguntarse ¿cuáles son las condiciones de vida y situaciones de riesgo de los adolescentes en el VRAEM? y ¿cuáles son las alternativas para una mejora de su situación desde el acceso a la educación y los programas de atención de su salud? Esta situación de riesgo es el resultado de las relaciones desiguales de género, violencia sexual, deserción escolar, embarazo adolescente, consumo de alcohol y drogas, así como de la falta de oportunidades como consecuencia de la participación en la economía de la coca y el narcotráfico entre los adolescentes en el VRAEM. Finalmente, se presentan los resultados de la atención de profesionales de los centros de salud para favorecer la consejería en salud sexual y reproductiva y el acceso a los servicios de salud del Programa Vida Adolescente, como oportunidad de vincular los contenidos del currículo de educación y las metas de cumplimiento de este sector, visibilizando la necesidad de un enfoque de interculturalidad e igualdad de género en el acceso a la salud y la educación de los adolescentes.

Senior High School English National Examination and Thinking Skills

Directory of Open Access Journals (Sweden)

Ummu Lathifah Ahmad

2016-12-01

Full Text Available When English National Examination (abbreviated into ENE as a norm-referenced test is designed for instructional purposes, to evaluate the result of national curriculum, it is very significant to conduct item test evaluation since it gives a clear portrait of the quality of the items and of the test as a whole. The purpose of this study was to analyze which levels of the Barrett taxonomy were more reflected in ENE items of 2013/2014 academic year and whether the proportions of items among the twenty test packages in the ENE assessing students’ Lower Order Thinking Skills (LOTS and Higher Order Thinking Skills (HOTS are consistent. The researcher adopted the qualitative descriptive approach using a content analysis card to codify the ENE items. To ensure the reliability of the study, three inter-raters analyzed a sample of the test packages. The results indicated that questions asking LOTS still prevailed in ENE items. Of all the twenty test packages, the items categorized into literal level represented around 68.6% of the total number of the questions. Meanwhile, the questions belonging to reorganization came to occupy a percentage of 20.8 and the questions asking the students’ inferential level only reached 10.3%. Also, the tests were not enriched sufficiently with the evaluation comprehension since they only comprised 0.3%. The results also showed the complete absence of “Appreciation” – the highest level of thinking in the mentioned taxonomy. It is obvious that there is a shortage of items questioning students’ HOTS in the exam and they are not well-treated. Accordingly, this finding reveals that there is still much room for ENE to be the driving force in the effort to make learners critical thinkers. In the light of these data, this study recommends modifying the English National Exam by providing them with more question items that include HOTS.

Eesti animafilm külvab uusi seemneid / Mari-Liis Rebane

Index Scriptorium Estoniae

Rebane, Mari-Liis

2009-01-01

PÖFFi alafestivalil Animated Dreams linastunud neljast uuest filmist: Olga ja Priit Pärna "Tuukrid vihmas", Kaspar Jancise "Krokodill", Martinus Daane Klemeti "Õhus" ja Girlin Bassovskaja (Jelena Girlin, Mari-Liis Bassovskaja) "Oranus"

"Troonide mäng" toob fantaasia usutavalt teleekraanile / Mari Rebane

Index Scriptorium Estoniae

Rebane, Mari

2011-01-01

USA telekanali HBO telesarjast "Troonide mäng", George R. R. Martini "Jää ja tule laulu" sarja esimese raamatu "Troonide mäng" teleekraniseeringust. Sarja esimene osa esilinastus USA-s 17. aprillil. Osades Sean Bean jt.

VAT-teatris mõtiskletakse allasurutud pingete üle / Mari Rebane

Index Scriptorium Estoniae

Rebane, Mari

2006-01-01

13. apr. esietendus VAT Teatris Amélie Nothombi "Vaenlase kosmeetika", tõlkija, lavastaja ja muusikaline kujundaja Peeter Raudsepp, kunstnik Hardi Volmer. Tükki mängitakse rahvusraamatukogu teatrisaalis

Koolid saavad tagasi algusaegade väärikuse / Mari Rebane

Index Scriptorium Estoniae

Rebane, Mari

2003-01-01

Artur Perna projekteeritud Tallinna 21. keskkooli hoone renoveerimisprojekti autor on Raul Järg, sisekujundaja Toomas Korb, lühtrite disainer Tõnis Vellama. Edgar Johan Kuusiku projekteeritud Lenderi tütarlastegümnaasiumi (Tallinna kesklinna vene gümnaasium) renoveerimisprojekti autor on Andres Põime, sisekujundaja Tiiu Truus

Potteri-raamatut esitletakse teemakohaste üritustega / Mari Rebane, Helen Uldrich

Index Scriptorium Estoniae

Rebane, Mari

2005-01-01

26. nov. korraldavad suuremad raamatukauplused Tallinnas, Tartus ja Pärnus Potteri teemalisi üritusi seoses Joanne Kathleen Rowling'i "Harry Potter ja segavereline prints" ilmumisega eesti keeles (tlk. Krista ja Kaisa Kaer). Vt. ka Postimees, 24. nov., lk. 18, SL Õhtuleht, 24. nov., lk. 14

PÖFF-i festivalid pakuvad aina paremat programmi / Margit Rebane

Index Scriptorium Estoniae

Rebane, Margit

2004-01-01

VIII Pimedate Ööde filmifestivali alafestivalid : tudengifilmifestival Sleepwalkers, laste- ja noortefilmide festival Just Film, animafilmifestival Animated Dreams (korraldajad Katrin Rajasaare, Elen Lotman, Heilika Võsu). Lisa : Kus toimub? Palju maksab?

Samal teemal : kas karistus või võimalused? / Epp Rebane

Index Scriptorium Estoniae

Rebane, Epp, 1954-

2003-01-01

Vastukaja art.: Kala, Mairoos and Veskioja, Andrus. Klassist klassi määruse abil ... // Õpetajate Leht (2003) 30. mai.1996/1997. õa kehtima hakanud HM-i määrus nr 26 13. novembrist lubab klassikursuse kordajaid kas või kõigis ainetes puudulike hinnetega järgmisse klassi üle viia (kolmandaks aastaks samasse klassi jätta ei tohi). Selle tagajärjel suureneb iga aastaga klassikursuse kordajate ja järgmisse klassi üle viidavate õpilaste arv

Lidar - nesbõvshajasja estonskaja "nokia" / Karl Rebane ; interv. Julia Rodina

Index Scriptorium Estoniae

Rebane, Karl, 1926-2007

2006-01-01

Eesti NSV teadlaste poolt välja töötatud laserseade lidar, seadme ehitamisest, töötamise põhimõttest ja kasutusvaldkonnast. Akadeemik Karl Rebase sõnul ei oleks sellise ulatusega Läänemere saastamist juhtunud, kui Eestil oleks normaalne ökoloogilise kontrolli süsteem. Poliitikute suhtumisest kodumaise teaduse arengusse

Synthesis, characterization and anticancer studies of new steroidal oxadiazole, pyrrole and pyrazole derivatives

Directory of Open Access Journals (Sweden)

Shamsuzzaman

2015-07-01

Full Text Available In the present study steroidal derivatives, 3β-[5′-mercapto-1′,3′,4′-oxadiazole-2-yl]methoxy cholest-5-ene 2, 3β-[2′,5′-dimethylpyrrole-1-yl]aminocarbonylmethoxycholest-5-ene 3 and 3β-[3′,5′-dimethyl pyrazole-1-yl]carbonylmethoxycholest-5-ene 4 have been synthesized from cholest-5-en-3β-O-acetyl hydrazide 1 using CS2/KOH, acetonyl acetone and acetyl acetone, respectively as reagents and are characterized by IR, 1H NMR,13C NMR, MS and elemental analysis. Compounds 2–4 were also evaluated for anticancer activity against human leukemia cell line (HL-60 by MTT assay and compound 4 displayed the promising behavior by showing better anticancer activity.

Effect of tibolone and its principal metabolites (3α- and 3β-hydroxy, 3α-sulfate, and 4-ene derivatives) on estrone sulfatase activity in normal and cancerous human breast tissue.

Science.gov (United States)

Chetrite, Gérard S; Cortes-Prieto, Joaquin; Pasqualini, Jorge R

2011-12-01

Tibolone (Org-OD14) is the active substance of Livial®, a synthetic steroid with the structure 7α,17α-17-hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3-one, possessing weak tissue-specific estrogenic, progestogenic, and androgenic properties, used to treat menopausal complaints. After oral administration, tibolone is extensively metabolized into the 3α-(Org-4904) and 3β-(Org-30126) hydroxy derivatives with estrogenic properties, its 4-ene (Org-OM38) isomer with progestogenic/androgenic activities, and the 3α-sulfate (Org-34322) derivative, a major biologically inactive circulating form. We compared the dose response of tibolone and its metabolites on estrone sulfatase activity [conversion of estrone sulfate (E1S) to estrone (E1)] in normal and cancerous human breast tissues. Tissue minces were incubated with physiological concentrations of [3H]-E1S (5×10-9M) alone or in the presence of tibolone and its metabolites (concentration range: 5×10-7to 5×10-5M) for 4 h. Tritiated E1, estradiol (E2), and E1S were separated and evaluated quantitatively by thin-layer chromatography. The sulfatase activity was significantly higher in cancerous breast but strongly inhibited by tibolone and the different metabolites, whereas 3α- and 3β-hydroxy derivatives were the most potent inhibitors. This very significant inhibitory effect of tibolone and its principal metabolites on the enzyme involved in E2biosynthesis in the human breast provides interesting perspectives to study the biological responses of these compounds in trials with breast cancer patients.

Proof of the Structure of the Stemodia chilensis Tetracyclic Diterpenoid (+)-19-Acetoxystemodan-12-ol by Synthesis from (+)-Podocarpic Acid: X-ray Structure Determination of a Key Intermediate.

Science.gov (United States)

Leonelli, Francesca; Mostarda, Azzurra; De Angelis, Luca; Lamba, Doriano; Demitri, Nicola; La Bella, Angela; Ceccacci, Francesca; Migneco, Luisa M; Marini Bettolo, Rinaldo

2016-04-22

The first synthesis of (+)-19-acetoxystemodan-12-ol (1), a stemodane diterpenoid isolated from Stemodia chilensis, is described. The structure was supported by an X-ray crystallographic analysis of intermediate (+)-9a, which confirmed the proposed structure and excluded the structure of (-)-19-hydroxystemod-12-ene as a possible candidate for the Chilean Calceolaria diterpenoid to which the (-)-19-hydroxystemar-13-ene structure (9b) had been erroneously assigned.

Villa Draiver / Mihkel Karu ; kommenteerinud Terje Truumaa

Index Scriptorium Estoniae

Karu, Mihkel, 1983-

2009-01-01

Villa Draiver (160 m2) Kuressaares Kotkapoja tänaval. Arhitekt ja sisearhitekt Terje Truumaa. Ehitaja: AS Kuressaare Ehitus. Valmis: 2008. Valdavas osas laia püstise helebeeži laudisega kaetud monoliitbetoonist hoone on mõeldud väljaüürimiseks golfihuvilistele

Roostetav legomaja / Karen Jagodin ; kommenteerinud Laila Põdra

Index Scriptorium Estoniae

Jagodin, Karen, 1982-

2009-01-01

Betoonelementidest eramu (267 m²) Tabasalus. Arhitekt Laila Põdra, insener Indrek Laul. Sisekujundus: Laila Põdra koos omanikega. Projekt: 2005-2007, valmis: 2008. Betoon on viimistluspinnaks ka interjööris. Läbivaks tooniks sise- ja välisviimistluses on roostepunane, teiseks põhitooniks on valge. Konkursil "Aasta Betoonehitis 2008" pälvis tellija eripreemia

Karakteriga kodu / Karen Jagodin ; kommenteerinud Enn Rajasaar

Index Scriptorium Estoniae

Jagodin, Karen, 1982-

2009-01-01

2008. aastal valminud 2-korruseline eramu Mähel. Arhitekt Enn Rajasaar. Sisearhitekt Aet Seire. Välisviimistluses on kombineeritud tumedat tellist ja heledat krohvi. Sisekujundust läbivad värvid punane ja must. Osa mööbliesemeid (raamatukapid, söögitoa laud) valmisid sisearhitekti erilahendusena

Malchiki malchiki! / Ahto Sooaru ; kommenteerinud Antti Parve

Index Scriptorium Estoniae

Sooaru, Ahto

2009-01-01

Antti Parve fotonäitusest "Malchiki malchiki". Fotosid sõdurpoistest on eksponeeritud erineval viisil Tapa väljaõppekeskuse õppehoones, Tallinna Loomaaias, Ambulartooriumi galeriis Kasepääl ja Vanemuise kontserdimaja fuajees. Fotograaf meenutab ajateenistust Eesti Kaitseväes

The in vitro biosynthesis of epitestosterone and testosterone from C19 steroid precursors in the testis of the lizard Tiliqua rugosa

International Nuclear Information System (INIS)

Huf, P.A.; Bourne, A.R.; Watson, T.G.

1989-01-01

The metabolism of androgens in the testis of the lizard Tiliqua rugosa has been studied in vitro by incubating cellular homogenates with radiolabeled C19-steroid substrates. The identification 17 beta-oxidoreductase and 3 beta-hydroxysteroid dehydrogenase/isomerase activities. Aromatase, 5 alpha-reductase, and 17 alpha/beta-epimerase activities were not detected. The 17 alpha-oxidoreductase activity was temperature dependent (maximal at 32 degrees), while the 17 beta-oxidoreductase activity was temperature independent. Time yield and dual-label studies indicated that testosterone biosynthesis mainly involves the 4-ene pathway (via androstenedione), whereas the formation of epitestosterone uses both the 4-ene and 5-ene (via 5-androstene-3 beta, 17 alpha-diol) pathways. The function of alternative pathways in androgen biosynthesis is discussed, as is the role of temperature in the intratesticular regulation of androgen production

Transformations in the field of college education

DEFF Research Database (Denmark)

Bøje, Jakob Ditlev

Paperet er kort version af den ene af mine analyser i ph.d.-projektet. Det drejer sig om en historisk diskursanalyse af transformationer af lærer- og pædagoguddnnnelse fra 60'erne til i dag.......Paperet er kort version af den ene af mine analyser i ph.d.-projektet. Det drejer sig om en historisk diskursanalyse af transformationer af lærer- og pædagoguddnnnelse fra 60'erne til i dag....

Project Lifespan-based Nonstationary Hydrologic Design Methods for Changing Environment

Science.gov (United States)

Xiong, L.

2017-12-01

Under changing environment, we must associate design floods with the design life period of projects to ensure the hydrologic design is really relevant to the operation of the hydrologic projects, because the design value for a given exceedance probability over the project life period would be significantly different from that over other time periods of the same length due to the nonstationarity of probability distributions. Several hydrologic design methods that take the design life period of projects into account have been proposed in recent years, i.e. the expected number of exceedances (ENE), design life level (DLL), equivalent reliability (ER), and average design life level (ADLL). Among the four methods to be compared, both the ENE and ER methods are return period-based methods, while DLL and ADLL are risk/reliability- based methods which estimate design values for given probability values of risk or reliability. However, the four methods can be unified together under a general framework through a relationship transforming the so-called representative reliability (RRE) into the return period, i.e. m=1/1(1-RRE), in which we compute the return period m using the representative reliability RRE.The results of nonstationary design quantiles and associated confidence intervals calculated by ENE, ER and ADLL were very similar, since ENE or ER was a special case or had a similar expression form with respect to ADLL. In particular, the design quantiles calculated by ENE and ADLL were the same when return period was equal to the length of the design life. In addition, DLL can yield similar design values if the relationship between DLL and ER/ADLL return periods is considered. Furthermore, ENE, ER and ADLL had good adaptability to either an increasing or decreasing situation, yielding not too large or too small design quantiles. This is important for applications of nonstationary hydrologic design methods in actual practice because of the concern of choosing the emerging

Uloga radnog terapeuta u rehabilitaciji oboljelih od šizofrenije

OpenAIRE

Radić, Saša; Škrbina, Dijana

2011-01-01

Mentalno zdravlje je esencijalni čimbenik za aktivno i neovisno funkcioniranje u svim aspektima života. Poremećaji mentalnog zdravlja značajno narušavaju svakodnevno življenje, te uzrokuju disbalans u tri područja čovjekovih aktivnosti: samozbrinjavanju, produktivnosti i slobodnom vremenu. Odabir, organiziranje i aktivna participacija u produktivnim aktivnostima pojedinca narušenog mentalnoga zdravlja značajno su ograničene i/ili onemogućene zbog smanjene motivacije, nemogućnosti zadovo...

POTENCIJALI PRIMJENE INTEGRIRANIH SUSTAVA UPRAVLJANJA U NAFTNOJ INDUSTRIJI

OpenAIRE

Lulić, Lukša

2014-01-01

S obzirom na svoje posebnosti, određene industrije i sektori moraju posjedovati specifične i rigorozne sustave upravljanja te su u skladu s takvim zahtjevima razvile industrijski specifične zahtjeve i standarde. Razlozi takvih aktivnosti uključuju upravljanje rizicima, spoznaju specifičnih zahtjeva određene industrije, sukladnost sa zakonskim i regulatornim zahtjevima te jačanje povjerenja u proizvode i procese dobavljača. Nafta je polivalentni energent, a naftna industrija podrazumijeva m...

Kadriorust leiate pargiraamatukogu / Ene Tamsalu

Index Scriptorium Estoniae

Tamsalu, Ene

2009-01-01

2006. aastal avati Kadrioru Pargi raamatukogu, mille kogu aluseks on soome maastikuarhitektuuri professori Tuula Maria Merivuori pärandatud erialaraamatukogu, kus leiab kirjandust maastiku-, pargi- ja aiaarhitektuurist, linna- ja regionaalplaneerimisest, botaanikast ja aiandusest

Riik arhitektuuritellijana / Ene Läkk

Index Scriptorium Estoniae

Läkk, Ene, 1957-

2010-01-01

Näidete varal Riigi Kinnisvara AS-i korraldatud projekteerimise hangetest, mil välja valiti odavaim pakkumine. Valminud Rakvere politseihoonest ning Jõgeva kohtu- ja politseihoonest. Mudelprojekteerimise (BIM) nõudest. Riigihankest kui salastatud protsessist. Sunnist loobuda autoriõigusest. Riigihankega ühendatud arhitektuurikonkursist

Tohuvabohu kodukujunduses / Ene Läkk

Index Scriptorium Estoniae

Läkk, Ene, 1957-

2000-01-01

Tänapäeva Eesti kodukujundusest. Illustratsiooniks 90ndate kolm eramut : neomodernistlik Sinine Maja neominimalistliku interjööriga (Kolm Pluss Üks Arhitektid, arhitekt M. Kaasik), modernistlik villa Sumberg - (Urbel & Peil, arhitekt E. Urbel, sisekujundaja T. Mähar), ökosugemetega modernistlik villa Koger (arhitekt V. Sova, sisearhitektid A. Teigar, M. Press). Kommenteerivad Mart Kalm, Toivo Raidmets. Terminite selgitus.

Armastus esimesest pilgust / Ene Vool

Index Scriptorium Estoniae

Vool, Ene, 1948-

2005-01-01

Annika Tederi jaapani stiilis aiast kui tähtsast osast eluruumis, mille kujundamisel on abiks olnud Liina Rehepapp. Jaapani aedadest, jaapanlaste suhtumisest aiakunsti ja lisaks artikkel "Eriilmelised ja -otstarbelised jaapani aiad"

Messiuudised : Maison & Objet / Ene Jakobi

Index Scriptorium Estoniae

Jakobi, Ene

2008-01-01

Uusi trende kõige suuremalt disainimessilt Maison & Objet Prantsusmaal - Jean-Charles de Castelbajaci joonistatud toolid, Jean-Christophe Bernardi pleksiklaasist tool ja laud, Joseph Licciardi ja Paul Coheni-Philipp Veenendaali etanoolil põlevad kaminad, Philippe Lebru kellad, Vincenzo Antonuccio vaasid ja Anna Siedlecka ning Radek Achramoviczi täispuhutavad valgustid

Maytenus distichophylla and Salacia crassifolia: source of products with potential acetylcholinesterase inhibition

Directory of Open Access Journals (Sweden)

Fernanda L. Ferreira

Full Text Available ABSTRACT The phytochemical study of the extract leaves from Maytenus distichophylla Mart. and Salacia crassifolia (Mart. ex Schult. G. Don, Celastraceae, resulted in the isolation of 3-oxofriedelane, 3β-hydroxyfriedelane, 3β,24-dihydroxyfriedelane, 3-oxo-28,29-dihydroxyfriedelane, two mixtures of pentacyclic triterpenes (α-amyrin with β-amyrin and 3β-stearyloxy-urs-12-ene with 3β-stearyloxy-olean-12-ene, 3β-palmityloxy-urs-12-ene, the steroid β-sitosterol and its glycosylated derivative β-glucosyl-β-sitosterol, tritriacontanoic acid and the natural polymer gutta percha. The chemical structures of these constituents were established by IR, 1H and 13C NMR spectral data. Crude extracts, the mixtures of triterpenes and the isolated constituents were subjected to in vitro acetylcholinesterase inhibitory evaluation. Acetylcholinesterase inhibitory effect was observed for crude chloroform extract leaves from M. distichophylla (100% and S. crassifolia (97.93 ± 5.63% and for the triterpenes 3β,24-dihydroxyfriedelane (99.05 ± 1.12%, 3-oxo-28,29-dihydroxyfriedelane (90.59 ± 3.76% and 3β-palmityloxy-urs-12-ene (97.93 ± 1.47%. The percent inhibitions induced by these natural products were very similar to those produced by physostigmine (93.94 ± 2.10% a standard acetylcholinesterase inhibitor. Therefore, these results open perspectives for the use of these species as source of compounds with similar physostigmine pharmacological effect.

Estudo fitoquímico da madeira de Guarea macrophylla (Meliaceae Phytochemical study of the wood from Guarea macrophylla (Meliaceae

Directory of Open Access Journals (Sweden)

João Henrique G. Lago

2009-01-01

Full Text Available In the present work, the crude ethanol extract from wood of G. macrophylla was submitted to liquid/liquid partition between hexane, CH2Cl2, EtOAc and n-BuOH. Each phase was individually chromatographed over silica gel, Sephadex LH-20 or Amberlite XAD-2 to give eight terpene derivatives, such as five sesquiterpenoids (caryophyllene oxide, guai-6-en-10β-ol, spathulenol, aromadendrane-4β,10α-diol and aloaromadendrane-4α,10β-diol as well as three triterpenoids (cicloart-24-ene-3β,23(R*-diol, cicloart-24-ene-3β,23(S*-diol, and cicloart-23E-ene-3β,25-diol. Additionally, were isolated three fatty acids (linolenic, linoleic and stearic, two steroids (sitosterol and stigmasterol and sacarose. The structures of all these compounds were characterized by spectrometric analysis, mainly mass spectrometry and NMR and comparison of these data described in the literature.

Osobnjak na beregu morja - lutshsheje betonnoje strojenije 2003 goda / Enno Rebane

Index Scriptorium Estoniae

Rebane, Enno, 1964-

2004-01-01

2003. a. parim betoonehitis - arhitekt Emil Urbeli kavandatud eramu (projekteerija TA Konsult OÜ, betoonitööde teostaja Mapri Projekt OÜ). Eriauhinna arhitektuurse lahenduse eest sai Siiri Vallneri, Hanno Grossschmidti ja Tomomi Hayashi kavandatud Lasnamäe spordihoone (projekteerija TA Konsult OÜ, ehitasid Eesti Ehitus OÜ, AS E-Betoonelement - ka betoonisegu tarnija) ja betoonitehnoloogia eest AS E-Betoonelement Ekseko seafarmi sõnnikuhoidla eest Viljandimaal. IV betoonipäevast

Eesti teeb koos soomlaste ja hiinlastega kung-fu filmi / Mari Rebane

Index Scriptorium Estoniae

Rebane, Mari

2005-01-01

Soome ja Hiina mütoloogiat ühendava fantaasiafilmi "Armuvalus sõdalane" (eelarve 39 milj. krooni) tootjad on Soome, Holland, Hiina ja Eesti (3,9 milj. krooni). Kaasa teeb ka Elle Kull, lavastab debütant AJ Annila

Mereröövlid saabusid suvist letargiat maha raputama / Mari Rebane

Index Scriptorium Estoniae

Rebane, Mari

2006-01-01

Esilinastus Gore Verbinski piraaditriloogia teine film "Kariibi mere piraadid : Surnud mehe aardekirst" : Ameerika Ühendriigid 2006. Lisaks lühendatud artikkel Los Angeles Times 10. juuli Josh Friedman "Piraadid püstitasid kassarekordi" ja katke ajalehele Guardian antud intervjuust Johnny Deppiga "Kapten Jack Sparrow laseb Deppil pingeid maandada"

EEG POLISOMNOGRAFIJA KAO ZNAČAJNA DIJAGNOSTIČKA I PROGNOSTIČKA METODA ZA PROCJENU OŠTEĆENJA MOZGA U NOVOROĐENČADI I DOJENČADI

OpenAIRE

Paškov Dugandžija, Gordana

2008-01-01

EEG polisomnografija je značajna metoda za dijagnozu i prognozu oštećenja mozga u nedonošene i donošene novorođenčadi i dojenčadi. Sadrži slijedeće elemente: EEG(elektroencefalografija), EOG( elektrookulografija) , EMG( elektromiografija), EKG (elektrokardiografija), respiracija i video monitoriranje. Primjenjujemo polisomnografsku montažu. To je specifično modificiran način postavljanja elektroda. Koristimo posrebrene pločaste elektrode sa 1 metar savitljivim silikonskim odvodima u šest razl...

Teatri aastaauhindade nominendid

Index Scriptorium Estoniae

2006-01-01

Lavastajaauhind : Merle Karusoo, Elmo Nüganen, Tiit Ojasoo, Ene-Liis Semper, Kristian Smeds, Hendrik Toompere jun, Ingomar Vihmar ; kunstnikuauhind : Iir Hermeliin, Liina Keevallik, Ene-Liis Semper, Aime Unt, Ervin Õunapuu ; naisnäitleja auhind : Ülle Kaljuste, Kaie Mihkelson, Harriet Toompere, Marika Vaarik, Liina Vahtrik ; meesnäitleja auhind : Ain Lutsepp, Rein Oja, Rain Simmul, Tarvo Sõmer, Tambet Tuisk, Aarne Üksküla ; Balleti- ja tantsuteater : Marina Tshirkova, Seki Hirotaka, Mari Savitski, Oksana Titova, Taavet Jansen, Sasha Pepeljajev, Katrin Essenson ja Tantsuteater Fine 5

Teatri aastaauhindadele kandideerijad selgunud

Index Scriptorium Estoniae

2006-01-01

Lavastajaauhind : Merle Karusoo, Elmo Nüganen, Tiit Ojasoo, Ene-Liis Semper, Kristian Smeds, Hendrik Toompere jun, Ingomar Vihmar ; kunstnikuauhind : Iir Hermeliin, Liina Keevallik, Ene-Liis Semper, Aime Unt, Ervin Õunapuu ; naisnäitleja auhind : Ülle Kaljuste, Kaie Mihkelson, Harriet Toompere, Marika Vaarik, Liina Vahtrik ; meesnäitleja auhind : Ain Lutsepp, Rein Oja, Rain Simmul, Tarvo Sõmer, Tambet Tuisk, Aarne Üksküla ; Balleti- ja tantsuteater : Marina Tshirkova, Seki Hirotaka, Mari Savitski, Oksana Titova, Taavet Jansen, Sasha Pepeljajev, Katrin Essenson ja Tantsuteater Fine 5

On rates and mechanisms of OH and O3 reactions with isoprene-derived hydroxy nitrates.

Science.gov (United States)

Lee, Lance; Teng, Alex P; Wennberg, Paul O; Crounse, John D; Cohen, Ronald C

2014-03-06

Eight distinct hydroxy nitrates are stable products of the first step in the atmospheric oxidation of isoprene by OH. The subsequent chemical fate of these molecules affects global and regional production of ozone and aerosol as well as the location of nitrogen deposition. We synthesized and purified 3 of the 8 isoprene hydroxy nitrate isomers: (E/Z)-2-methyl-4-nitrooxybut-2-ene-1-ol and 3-methyl-2-nitrooxybut-3-ene-1-ol. Oxidation of these molecules by OH and ozone was studied using both chemical ionization mass spectrometry and thermo-dissociation laser induced fluorescence. The OH reaction rate constants at 300 K measured relative to propene at 745 Torr are (1.1 ± 0.2) × 10(-10) cm(3) molecule(-1) s(-1) for both the E and Z isomers and (4.2 ± 0.7) × 10(-11) cm(3) molecule(-1) s(-1) for the third isomer. The ozone reaction rate constants for (E/Z)-2-methyl-4-nitrooxybut-2-ene-1-ol are (2.7 ± 0.5) × 10(-17) and (2.9 ± 0.5) × 10(-17) cm(3) molecule(-1) s(-1), respectively. 3-Methyl-2-nitrooxybut-3-ene-1-ol reacts with ozone very slowly, within the range of (2.5-5) × 10(-19) cm(3) molecule(-1) s(-1). Reaction pathways, product yields, and implications for atmospheric chemistry are discussed. A condensed mechanism suitable for use in atmospheric chemistry models is presented.

Olefins transformation catalysis by zirconium and tungsten complexes in organic and non-aqueous ionic media; Catalyse de transformation des olefines par les complexes du zirconium et du tungstene en milieux organique et ionique non aqueux

Energy Technology Data Exchange (ETDEWEB)

Laurent-Gerot, P

1997-06-30

Molten salts are suitable solvents for biphasic catalysis: melting butyl-1 methyl-3 imidazolium chloride and aluminium chloride gives a polar and aprotic ionic liquid which is not miscible with hydrocarbons but dissolves organometallic complexes. Two types of complexes have been tested in molten salts with ethyl-aluminium dichloride: zirconium complexes to synthesize light {alpha} olefins from ethene; mono-imido complexes of tungsten VI (Cl{sub 4}W = NAr) to dimerize ethene in but-1 ene and propene in dimethyl-2,3-but-1-ene. For both of these complexes, biphasic catalysis principle is always respected: the active species is present only in the ionic phase and not in the organic phase. The first complexes, biphasic principle is always respected: the active species is present only in the ionic phase and not in the organic phase. The first complexes oligomerize ethene in molten salts with low activity and the {alpha} olefins selectivity is weak. Mono-imido complexes of tungsten VI are proved to be equivalent to the systems composed with WCl{sub 6} and aniline, and they dimerize ethene in but-1 ene and propene in dimethyl-2,3-but-1 ene more efficiently in organic medium than in ionic liquid. The characterization of the active species of the system Cl{sub 4}W=NAr / EtAlCl{sub 2} shows that it is the corresponding mono-imido complex of tungsten 4. (author) 129 refs.

Agripinin portret u odnosu prema rimskim ženskim portretima s pulskog i nezakcijskog agera

OpenAIRE

Girardi Jurkić, Vesna; Džin, Kristina

2006-01-01

Za vrijeme zaštitnog arheološkog istraživanja (1987.-1988.) na forumu u Puli (Colonia Pola)otkrivena je mramorna ženska glava za koju se pretpostavlja da je portret Agripine Mlađe, ženecara Klaudija i majke cara Nerona. Skulptura je originalno vjerojatno bila postavljena na zidanojbazi u sjeveroistočnom zidu luksuzne prostorije popločene mramorom i ukrašene štukaturama nazidu kojega je baza bila ukrašena mramorom i štukom. Tri natpisa otkrivena u blizini tzv. Agripininekuće spominju careve Kl...

Role of unsaturated derivatives of spermidine as substrates for spermine synthase and in supporting growth of SV-3T3 cells.

OpenAIRE

Pegg, A E; Nagarajan, S; Naficy, S; Ganem, B

1991-01-01

Synthetic unsaturated analogues of the natural polyamine were examined as possible substrates for spermine synthase and as replacements for spermidine in supporting the growth of SV-3T3 cells. It was found that N-(3-aminopropyl)-1,4-diamino-cis-but-2-ene [the cis isomer of the alkene analogue of spermidine] was a good substrate for spermine synthase, but that the trans isomer [N-(3-aminopropyl)-1,4-diamino-trans-but-2-ene] and the alkene analogue [N-(3-aminopropyl)-1,4-diaminobut-2-yne] were ...

Thermal rearrangement of 7-methylbicyclo

Science.gov (United States)

Bender; Leber; Lirio; Smith

2000-08-25

The gas-phase thermal rearrangement of exo-7-methylbicyclo[3.2.0]hept-2-ene yields almost exclusively 5-methylnorbornene products. Inversion (i) of configuration dominates this [1,3] sigmatropic shift although some retention (r) is also observed. Because the [1,3] migration can only occur suprafacially (s) in this geometrically constrained system, the si/sr ratio of 7 observed for the migration of C7 in exo-7-methylbicyclo[3.2.0]hept-2-ene indicates that the orbital symmetry rules are somewhat permissive for the [1,3] sigmatropic migration of carbon.

Antiproliferative Compounds of Cyphostemma greveana from a Madagascar Dry Forest[1

OpenAIRE

Cao, Shugeng; Hou, Yanpeng; Brodie, Peggy; Miller, James S.; Randrianaivo, Richard; Rakotobe, Etienne; Rasamison, Vincent E.; Kingston, David G. I.

2011-01-01

Bioassay-guided fractionation of the EtOH extracts obtained from a plant identified as Cyphostemma greveana Desc. (Vitaceae) led to the identification of one macrolide, lasiodiplodin (1), three sesquiterpenoids, 12-hydroxy-15-oxo-selina-4,1l-diene (2), 1β,6α-dihydroxyeudesm-4(15)-ene (3), and (7R*)-opposit-4(15)-ene-1β,7-diol (5), and the new diterpenoid, 16,18-dihydroxykolavenic acid lactone (4). All the isolates were tested against the A2780 human ovarian cancer cell line, and compound 4 an...

Terpenoid constituents from leaves of Guarea kunthiana

International Nuclear Information System (INIS)

Garcez, Fernanda R.; Garcez, Walmir S.; Bazzo, Rita de Cassia; Silva, Ana Francisca G. da; Resende, Ubirazilda M.

2004-01-01

From leaves of Guarea kunthiana one new kaurene diterpene (ent-kaur-16-en-2-one) was isolated along with eight known diterpenes (ent-kaur-16-ene, ent-3α- and 3β-hydroxykaur-16-ene, kolavelool, kolavenol, kolavenal, ent-13-epi-manoyloxide and (-)-nephthenol), four sesquiterpenes (alismol, alismoxide, spathulenol and 4β,10α-aromadendranediol), polyprenol-12 and α- and δ-tocopherols. Kolavenal is reported for the first time as a natural product, as well as the occurrence of cembrane- and ent-kaurane-type diterpenes in the Meliaceae. (author)

Linnalood / Andri Ksenofontov ; kommenteerinud R[eet] V[arblane

Index Scriptorium Estoniae

Ksenofontov, Andri, 1962-

2010-01-01

Erki Kasemetsa näitus "Kohad/Cities Revealed" ja Liina Siibi näitus "Gimme Danger" sarjast "Cityscape" Tallinna Linnagaleriis. Näitus "Jüri Kaarma lugemistuba" Vabaduse Galeriis. Rühmituse Johnson&Johnson näitus "Nothing Left to Save" Draakoni galeriis. Karel Koplimetsa, Sigrid Viiri ja Taaniel Raudsepa kunstiprojekt "OÜ Visible Solutions" Hobusepea galeriis. Inglise kunstniku Pamela June Crooki isikunäitus galeriis Vaal. Peeter Lauritsa fotonäitus "Trickster's Office" ArtDepoo galeriis

Kas usud seda? / Loore Ehrlich ; kommenteerinud Remo Savisaar

Index Scriptorium Estoniae

Ehrlich, Loore

2013-01-01

Müüdid: Talvituvad herilased kaitsevad pesa raevukalt; Karu tõuseb enne ründamist tagajalgadele; Kõik ämblikud on ohtlikult mürgised; Puuk kukutab end puude-põõsaste okstelt inimesele; Kõrvahark ronib kõrva ja sealt edasi ajju; Rästik jälitab inimest eesmärgiga rünnata; Nahkhiir on verdihkav vampiir; Ilves ründab inimest puuvõrast turja karates; Näljased hundid murravad inimesi; Sosnovski karuputk kõrvetab; Seen mis ussitab on söögi seen

Tudengid tulid appi / Kaupo Kala ; kommenteerinud Heikki Zoova

Index Scriptorium Estoniae

Kala, Kaupo

2010-01-01

Koristustarvikuid ja -vahendeid tootval ettevõttel KH Teh Production OÜ valmisid koostöös Eesti Kunstiakadeemia tootedisaini osakonnaga ettevõtte tootearendusprojekt, disaini juhtimise kava, uus pakendisüsteem, stiiliraamat, arendati uusi tooteid. Töörühma, kuhu kuulusid neli üliõpilast ja kaks firma töötajat, juhtis EKA tootedisaini osakonna juhataja Heikki Zoova

Arhitekti pilguga betoonist / Madis Eek ; kommenteerinud Maritta Koivisto

Index Scriptorium Estoniae

Eek, Madis, 1966-

2011-01-01

Žürii liige konkursist "Aasta Betoonehitis 2010". Eramu Pirital Vahtramäe tee 9 - peaauhind, arhitekt Andres Lember. Eesti Maanteemuuseumi välialad - eriauhind tervikliku arhitektuurse lahenduse eest: AB Salto, graafilise betooni idee eest: Laika, Belka & Strelka. Tehvandi spordikeskuse suusastaadion - eriauhind betoonitöö eest: OÜ Savekate (arhitekt Raine Karp). Must maja Nõmmel - terviklahenduse ja betoonitöö eriauhind: arhitekt Martin Aunin, Nordecon Betoon OÜ

Hydrolysis of strained bridgehead bicyclic vinyl ethers and sulfides

International Nuclear Information System (INIS)

Chwang, W.K.; Kresge, A.J.; Wiseman, J.R.

1979-01-01

Rates of hydrolysis of the bridgehead bicyclic vinyl ether 9-oxabicyclo[3.3.1]non-1-ene(6) and its vinyl sulfide counterpart 9-thiabicyclo[3.3.1]non-1-ene(7), catalyzed by the hydronium ion, were measured in H 2 O and in D 2 O solution. These data give isotope effects, k/sub H//k/sub D/ = 2.4 and 1.9 respectively, which show that these reactions occur by the normal, rate-determining carbon protonation, mechanism. The vinyl ether 6 is less reactive than its olefin analogue, bicyclo[3.3.1]non-1-ene (relative rate 1:1/1400), as may have been expected for a constrained bicyclic system such as this, where stabilization of the bridgehead carbocation intermediate by conjugation with oxygen is severely impaired. The vinyl sulfide 7, however, is even less reactive than the vinyl ether (relative rates 1:1/140); this is a remarkable result in view of the fact that conjugation between the sulfur atom and the cationic center is presumably also strongly inhibited. 1 figure, 3 tables

Hollow Nanospheres Array Fabrication via Nano-Conglutination Technology.

Science.gov (United States)

Zhang, Man; Deng, Qiling; Xia, Liangping; Shi, Lifang; Cao, Axiu; Pang, Hui; Hu, Song

2015-09-01

Hollow nanospheres array is a special nanostructure with great applications in photonics, electronics and biochemistry. The nanofabrication technique with high resolution is crucial to nanosciences and nano-technology. This paper presents a novel nonconventional nano-conglutination technology combining polystyrenes spheres (PSs) self-assembly, conglutination and a lift-off process to fabricate the hollow nanospheres array with nanoholes. A self-assembly monolayer of PSs was stuck off from the quartz wafer by the thiol-ene adhesive material, and then the PSs was removed via a lift-off process and the hollow nanospheres embedded into the thiol-ene substrate was obtained. Thiolene polymer is a UV-curable material via "click chemistry" reaction at ambient conditions without the oxygen inhibition, which has excellent chemical and physical properties to be attractive as the adhesive material in nano-conglutination technology. Using the technique, a hollow nanospheres array with the nanoholes at the diameter of 200 nm embedded into the rigid thiol-ene substrate was fabricated, which has great potential to serve as a reaction container, catalyst and surface enhanced Raman scattering substrate.

Cytochrome P-450-catalyzed desaturation of valproic acid in vitro. Species differences, induction effects, and mechanistic studies

International Nuclear Information System (INIS)

Rettie, A.E.; Boberg, M.; Rettenmeier, A.W.; Baillie, T.A.

1988-01-01

The cytochrome P-450-mediated desaturation of valproic acid (VPA) to its hepatotoxic metabolite, 2-n-propyl-4-pentenoic acid (4-ene-VPA), was examined in liver microsomes from rats, mice, rabbits and humans. The highest substrate turnover was found with microsomes from rabbits (44.2 +/- 2.7 pmol of product/nmol P-450/15 min), while lower activities were observed in preparations from human, mouse, and rat liver, in that order. Pretreatment of animals with phenobarbital led to enhanced rates of formation of 4-ene-VPA in vitro and yielded induction ratios for desaturation ranging from 2.5 to 8.4, depending upon the species. Comparative studies in the rat showed that phenobarbital is a more potent inducer of olefin formation than either phenytoin or carbamazepine. The mechanism of the desaturation reaction was studied by inter- and intramolecular deuterium isotope effect experiments, which demonstrated that removal of a hydrogen atom from the subterminal C-4 position of VPA is rate limiting in the formation of both 4-ene- and 4-hydroxy-VPA. Hydroxylation at the neighboring C-5 position, on the other hand, was highly sensitive to deuterium substitution at that site, but not to deuteration at C-4. Based on these findings, it is proposed that 4-ene- and 4-hydroxy-VPA are products of a common P-450-dependent metabolic pathway, in which a carbon-centered free radical at C-4 serves as the key intermediate. 5-Hydroxy-VPA, in contrast, derives from an independent hydroxylation reaction

6-Oxocyclohex-1-ene-1-carbonyl-coenzyme A hydrolases from obligately anaerobic bacteria: characterization and identification of its gene as a functional marker for aromatic compounds degrading anaerobes.

Science.gov (United States)

Kuntze, Kevin; Shinoda, Yoshifumi; Moutakki, Housna; McInerney, Michael J; Vogt, Carsten; Richnow, Hans-Hermann; Boll, Matthias

2008-06-01

In anaerobic bacteria, most aromatic growth substrates are channelled into the benzoyl-coenzyme A (CoA) degradation pathway where the aromatic ring is dearomatized and cleaved into an aliphatic thiol ester. The initial step of this pathway is catalysed by dearomatizing benzoyl-CoA reductases yielding the two electron-reduction product, cyclohexa-1,5-diene-1-carbonyl-CoA, to which water is subsequently added by a hydratase. The next two steps have so far only been studied in facultative anaerobes and comprise the oxidation of the 6-hydroxyl-group to 6-oxocyclohex-1-ene-1-carbonyl-CoA (6-OCH-CoA), the addition of water and hydrolytic ring cleavage yielding 3-hydroxypimelyl-CoA. In this work, two benzoate-induced genes from the obligately anaerobic bacteria, Geobacter metallireducens (bamA(Geo)) and Syntrophus aciditrophicus (bamA(Syn)), were heterologously expressed in Escherichia coli, purified and characterized as 6-OCH-CoA hydrolases. Both enzymes consisted of a single 43 kDa subunit. Some properties of the enzymes are presented and compared with homologues from facultative anaerobes. An alignment of the nucleotide sequences of bamA(Geo) and bamA(Syn) with the corresponding genes from facultative anaerobes identified highly conserved DNA regions, which enabled the discrimination of genes coding for 6-OCH-CoA hydrolases from those coding for related enzymes. A degenerate oligonucleotide primer pair was deduced from conserved regions and applied in polymerase chain reaction reactions. Using these primers, the expected DNA fragment of the 6-OCH-CoA hydrolase genes was specifically amplified from the DNA of nearly all known facultative and obligate anaerobes that use aromatic growth substrates. The only exception was the aromatic compound-degrading Rhodopseudomonas palustris, which uniquely uses a modified benzoyl-CoA degradation pathway. Using the oligonucleotide primers, the expected DNA fragment was also amplified in a toluene-degrading and a m

Stomatološki pregledi tijekom trudnoće

OpenAIRE

Polašek, Antonia

2017-01-01

Trudnoća je jedinstveno vrijeme u životu žene, popraćeno raznovrsnim fiziološkim, anatomskim i hormonskim promjenama koje mogu utjecati na pružanje oralne zdravstvene zaštite. Razumijevanje tih uobičajenih promjena nužno je za pružanje kvalitetne njege trudnica. Međutim, trudnice kao pacijenti nisu medicinski ugrožene i ne bi trebalo odgađati provođenje potrebnog dentalnog tretmana. U trudnoći se javljaju pojedine promjene stanja zubi i okolnog tkiva usne šupljine, ali se one većinom mogu...

Modification of the estrogenic properties of diphenols by the incorporation of ferrocene. Generation of antiproliferative effects in vitro.

Science.gov (United States)

Vessières, Anne; Top, Siden; Pigeon, Pascal; Hillard, Elizabeth; Boubeker, Leila; Spera, Daniela; Jaouen, Gérard

2005-06-16

We report here the synthesis and the strong and unexpected antiproliferative effect of the organometallic diphenolic compound 1,1-bis(4'-hydroxyphenyl)-2-ferrocenyl-but-1-ene (4) on both hormone-dependent (MCF7) and -independent (MDA-MB231) breast cancer cells (IC(50) = 0.7 and 0.6 microM). Surprisingly, 6 [1,2-bis(4'-hydroxyphenyl)-2-ferrocenyl-but-1-ene], the regioisomer of 4, shows only a modest effect on these cell lines. This pertinent organometallic modification seems to trigger an intracellular oxidation of the structurally favorable compound 4, leading to the generation of a potent cytotoxic compound.

Synthesis, antimicrobial and cytotoxicity evaluation of new cholesterol congeners

Directory of Open Access Journals (Sweden)

Mohamed Ramadan El Sayed Aly

2015-10-01

Full Text Available 3β-Azidocholest-5-ene (3 and (3β-3-(prop-2-yn-1-yloxycholest-5-ene (10 were prepared as substrates to synthesize a variety of three-motif pharmacophoric conjugates through CuAAC. Basically, these conjugates included cholesterol and 1,2,3-triazole moieties, while the third, the pharmacophore, was either a chalcone, a lipophilic residue or a carbohydrate tag. These compounds were successfully prepared in good yields and characterized by NMR, MS and IR spectroscopic techniques. Chalcone conjugate 6c showed the best antimicrobial activity, while the lactoside conjugate 27 showed the best cytotoxic effect in vitro.

Three New Multiflorane-Type Triterpenes from Pumpkin (Cucurbita maxima Seeds

Directory of Open Access Journals (Sweden)

Reiko Tanaka

2013-05-01

Full Text Available Three new multiflorane-type triterpenes; 7a-methoxymultiflor-8-ene-3a,29-diol 3-acetate-29-benzoate (1, 7-oxomultiflor-8-ene-3a,29-diol 3-acetate-29-benzoate (2, and multiflora-7,9(11-diene-3a,29-diol 3-p-hydroxybenzoate-29-benzoate (3, were isolated from seeds of Cucurbita maxima, along with three known compounds. Compound 3 and multiflora-7,9(11-diene-3a-29-diol 3-benzoate (5 exhibited potent inhibitory effects on melanogenesis, with low cytotoxicities, and 2 exhibited single-digit micromolar cytotoxicity against HL-60 and P388 cells.

Three new multiflorane-type triterpenes from pumpkin (Cucurbita maxima) seeds.

Science.gov (United States)

Kikuchi, Takashi; Takebayashi, Mika; Shinto, Mayumi; Yamada, Takeshi; Tanaka, Reiko

2013-05-14

Three new multiflorane-type triterpenes; 7a-methoxymultiflor-8-ene-3a,29-diol 3-acetate-29-benzoate (1), 7-oxomultiflor-8-ene-3a,29-diol 3-acetate-29-benzoate (2), and multiflora-7,9(11)-diene-3a,29-diol 3-p-hydroxybenzoate-29-benzoate (3), were isolated from seeds of Cucurbita maxima, along with three known compounds. Compound 3 and multiflora-7,9(11)-diene-3a-29-diol 3-benzoate (5) exhibited potent inhibitory effects on melanogenesis, with low cytotoxicities, and 2 exhibited single-digit micromolar cytotoxicity against HL-60 and P388 cells.

Gender stereotypes analysis in cartoons broadcasted on Croatian televisions

OpenAIRE

Rudančić, Vlatka

2015-01-01

Rodni stereotipi postoje od kada postoje muškarci i žene, njihovo značenje roda i spola. Od samih početaka razvoja pismenosti (od doba Aristotela) muškarci su bili oni koji su išli u lov i čije se mišljenje uvažavalo, dok su žene ostajale doma, rađale djecu i brinule se o njima. Istraživanje se temelji na osamdeset analiziranih crtanih filmova koji se prikazuju na hrvatskim nacionalnim TV postajama te prikazuju postojanje rodnih stereotipa u svim pregledanim materijalima. Metoda koja se koris...

Two new cucurbitane triterpenoids from the seeds of Momordica charantia.

Science.gov (United States)

Ma, Lin; Yu, Ai-Hua; Sun, Li-Li; Gao, Wan; Zhang, Meng-Meng; Su, Ya-Lun; Liu, Hua; Ji, Teng-Fei; Li, Di-Zao

2014-01-01

Two new cucurbitane triterpenoids 1 and 2 were isolated, together with six known compounds, from the seeds of Momordica charantia L. The structures of new compounds were determined to be 3-O-{[β-d-galactopyranosyl(1 → 6)]-O-β-d-galactopyranosyl}-23(R), 24(R), 25-trihydroxycucur-bit-5-ene (1), 3-O-[β-d-galactopyranosyl]-25-O-β-d-galactopyranosyl-7(R), 22(S), 23(R), 24(R), 25-pentahydroxycucurbit-5-ene (2), respectively. Their structures were elucidated by the combination of mass spectrometry, one- and two-dimensional NMR experiments and chemical reactions.

Uus eesti disain / Ene Läkk

Index Scriptorium Estoniae

Läkk, Ene, 1957-

2009-01-01

2009. a. disainiöö raames toimunud Eesti Disainerite Liidu algatatud konkursi "Eesti disain ja elukeskond 2009" disainikategooria kümne finalisti tööde tutvustus. 1. koha sai moodulrattahoidja "Rohi" (disain: Keha3), 2. koha vurr-tool "Kiirendi" (disain: Jaanus Orgusaar), 3. koha lastemööbel "Smart kid" (disain: Pavel Sidorenko, Heiki Must)

Modernne kastmaja Nõmmel / Ene Läkk

Index Scriptorium Estoniae

Läkk, Ene, 1957-

1999-01-01

Projekteerija: arhitektuuribüroo Mark & Tamm. Konstruktiivne osa: inseneribüroo Randväli Karema. Arhitektid Ülar Mark, Kalle Komissarov. Kahekorruseline maja Vabaduse pst. ääres on mahutatud puude vahele kitsale alale. Kommenteerib Ü. Mark.

Ametlikke annetusi 2005. aastal / Ene Riet

Index Scriptorium Estoniae

Riet, Ene, 1954-

2005-01-01

Saksamaa suursaadik Julius Bobinger kinkis 50 saksakeelset "Kalevipoega" Eesti Kultuuriministeeriumile, kes edastas need maakonnaraamatukogudele, teadusraamatukogudele ja Kreutzwaldi muuseumile Võrus

Professor Pekka Puska loengud / Ene Indermitte

Index Scriptorium Estoniae

Indermitte, Ene, 1967-

2004-01-01

Soome Rahvatervishoiu Instituudi direktor, Põhja-Karjala projekti juht prof Pekka Puska peab Tartu ülikoolis loengu "The North Karelia Projekt in Finland and lessons for global chronic disease prevention"

Tagasivaade elule ja ajale / Ene Liivik

Index Scriptorium Estoniae

Liivik, Ene, 1933-

2010-01-01

Artikkel põhineb kahel käsikirjal "Tagasi waade möödunud elule ja ajale. Utškuju-Tarhani küla aja lugu. 50ne aastane juubel" ja "Lahtised lehed", mille autoriks on Helmi Koolmann. Käsikirjas meenutavad Helmi ja tema abikaasa Rein Koolmann Krimmis elatud aastaid

Hüdra aastasada / Ene-Reet Soovik

Index Scriptorium Estoniae

Soovik, Ene-Reet

1997-01-01

Arvustus: Galsworthy, John. Peatüki lõpp : Üle jõe / tlk. Jüri ja Liisi Ojamaa. Tallinn : Eesti Raamat, 1997; Amis, Kingsley. qnneseen Jim / tlk. Urve Hanko. Tallinn : Eesti Raadio, 1997; Boyd, William. Sinine pärastlõuna / tlk. Virve Krimm. Tallinn : Varrak, 1997. Briti XX saj. kirjanduse ülevaade

Vaesusriski muutused Eestis / Ene-Margit Tiit

Index Scriptorium Estoniae

Tiit, Ene-Margit, 1934-

2006-01-01

Seoses Eesti majanduse kiire arenguga tellis sotsiaalministeerium 2005. aastal uue tarbimiskaalude hinnangu, mille aluseks olid leibkonna eelarvehinnangu andmed aastaist 2000-2004 ning hinnati erineva struktuuriga leibkondade tarbimiskulutusi. Diagrammid. Graafikud

Küberjulgeolekule teed rajades / Ene Ergma

Index Scriptorium Estoniae

Ergma, Ene, 1944-

2007-01-01

Riigikogu esimees analüüsib aprillisündmustega kaasnenud küberrünnakute kui ühe terrorismi erivormi tagamaid, toob välja vajaduse kujundada küberrünnakute suhtes Euroopa Liidus ja NATO-s ühtne poliitika

Eesti Etnograafia Ring Kanadas / Ene Runge

Index Scriptorium Estoniae

Runge, Ene, 1919-1999

1993-01-01

Etnograafia Ring looodi 1971.a ja on pidevalt õpetanud käsitööd, pidanud loenguid eesti ja inglise keeles, korraldanud näitusi ja loonud eesti sektsiooni Royal Ontario Museumi ja Canadian National Museumi juurde kultuurivara säilitamiseks. Seltsi 20. aastapäevaks oli välja antud 61 õppekirja, lisaks õpetused ajakirjas "Triinu" ja õppefilmid, fotod ja diapositiivid, abi on antud samasugustele ringidele Rootsis ja Austraalias, ERM-ile saadeti 1991. a üle 200 rahvakultuuri eseme

ŽENE U ZNANOSTI: STAKLENI STROP

OpenAIRE

PRIJIĆ-SAMARŽIJA, Snježana; AVELINI HOLJEVAC, Ivanka; TURK, Marko

2009-01-01

Temeljni cilj članka jest propitivanje postojanja "staklenoga stropa" ili podzastupljenosti žena na rukovodećim položajima u ustanovama znanosti i visokog obrazovanja kakvo je Sveučilište u Rijeci, uključivo i mehanizama koji ga uzrokuju. Prvi dio članka sadrži kratak pregled i analizu empirijskih rezultata istraživanja provedenog na Sveučilištu u Rijeci, koji nedvojbeno upućuju na prisutnost efekta "staklenoga stropa" i, shodno tome, na postojanje prikrivene primarne i s...

Potter 3 ja Shrek 2 teevad puhta töö / Mari Rebane

Index Scriptorium Estoniae

Rebane, Mari

2004-01-01

J.K. Rowling'u Harry Potteri lugude kolmas film "Harry Potter ja Azkabani vang" ("Harry Potter and the Prisoner of Azkaban") : režissöör Alfonso Cuaron ja animafilm "Shrek 2" on suure kassaeduga maailmas võidukäigul ning tulevad ekraanile ka Eestis, animafilm seejuures eesti keelde dubleerituna

Sügiskaamose puhul tõttavad appi kolmed moepäevad / Mari Rebane

Index Scriptorium Estoniae

Rebane, Mari

2007-01-01

4.10.2007 alanud Tallinna moenädal Tallinn Fashion Week Estonia teatri kammersaalis toob vaatajateni kodumaiste moedisainerite loomingut. Moenädala raames toimub Viru keskuses ka sügisene FIBIT ning Montoni kauplustes Tallinnas ja Tartus antakse tasuta stiilinõuandeid

Ene Üleoja: "Kreeki ei ületa praegu keegi" / Ene Üleoja ; intervjueerinud T[iina] M[attisen

Index Scriptorium Estoniae

Üleoja, Ene, 1937-

2010-01-01

Heliloojate Liidu ja Pirita kloostri poolt välja kuulutatud heliloominguvõistluse "Taaveti laul" tulemustest žürii liikme E. Üleojaga. Konkursi lõppkontsert toimus 10. veebr. Pirita kloostris, esines Voces Musicales Endrik Üksvärava juhatusel

Mechanical Characterization of Polydopamine-Assisted Silver Deposition on Polymer Substrates

Science.gov (United States)

Cordes, Amanda Laurence

Inspired by the adhesive proteins in marine mussels, polydopamine has become a popular adhesive ad-layer for surface functionalization of a variety of substrates. Based on the chemistry of the dopamine monomer, amine and thiol functional groups are hypothesized to increase adhesion between polymer substrates and polydopamine thin films. This hypothesis was the central motivation for development of a tailorable thiol-ene system in order to study the effects of substrate chemistry on polydopamine adhesion. While polydopamine-adhered silver has been studied on a variety of substrates, no in depth mechanical characterization has been performed and to date, no research has been published on thiol-enes coated in polydopamine-adhered silver. The purpose of this study was to characterize the mechanical durability and adhesion properties of a polydopamine-adhered silver film on commercial substrates and a tailorable thiol-ene system. Polydopamine and silver coatings were deposited on a variety of polymer substrates through a simple dip-coat process. The polydopamine forms a thin uniform adhesive layer and the silver deposits in a discontinuous manner with a nanoparticle sized base layer covering the full surface and micron-sized clusters adhered sporadically on top. Mechanical tensile testing was performed to characterize the durability of the silver coating on commercial polymers. Coated nylon and HDPE showed no signs of degradation or delamination of the polydopamine-adhered silver coating up to 30% strain although both substrates showed large plastic deformation. Peel tests were performed on both commercial polymers as well as a tailorable thiol-ene system. Results support the hypothesis that polydopamine adhesion is increased with the presence of functional groups. Parts of the HDPE sample were cleanly peeled, but silver patches were left sporadically across the surface pointing to weaker adhesion between polyethylene and polydopamine. A high adhesive strength tape was

National Energy Strategy 2012-2026; Estrategia Nacional de Energia 2012-2026

Energy Technology Data Exchange (ETDEWEB)

Direccion General de Planeacion Estrategica, Secretaria de Energia, Mexico, D.F. (Mexico)

2012-02-15

In compliance with the provisions of the Congress, the National Energy Strategy 2012-2026 (NES) outlines the direction of the Mexican energy sector with a horizon of 15 years. Its vision is supported by a comprehensive planning exercise that collects information from each of the parastatals and decentralized administrative bodies that make up the sector. This ensures the accuracy and relevance of information presented throughout the document and integrates the perspectives of all public bodies involved. From that interagency and interdisciplinary approach, the NES provides energy policy guidelines that are essential to realize this vision. In turn, these serve to construct detailed criteria of public policy. Finally, the NES raises specific targets for 2026, which can be achieved based on the implementation of actions considered within the planning guidelines. The NES is a prospective tool and indicative that stands as a useful tool for any plan or program. To serve as an instrument of dialogue between institutions and authorities, NES is a document with a solid vision and a planned role in Mexico's energy policy. [Spanish] En cumplimiento por lo establecido por el Congreso de la Union, la Estrategia Nacional de Energia 2012-2026 (ENE) delinea el rumbo del sector energetico mexicano con un horizonte de 15 anos. Su vision esta sustentada en un ejercicio integral de planeacion que recaba informacion de cada una de las entidades paraestatales y organos administrativos desconcentrados que conforman el sector. Esto garantiza la precision y pertinencia de la informacion presentada a lo largo del documento e integra las perspectivas de todos los entes publicos involucrados. A partir de ese enfoque interinstitucional e interdisciplinario, la ENE establece los lineamientos de politica energetica que son indispensables para materializar esta vision. A su vez, estos sirven para construir criterios detallados de politica publica. Finalmente, la ENE plantea metas concretas

Exposure to volatile organic compounds in an ethanol and gasoline service station.

Science.gov (United States)

de Oliveira, K M P G; Martins, E M; Arbilla, G; Gatti, L V

2007-08-01

The present study was conducted to determine the VOCs concentrations in a service station located in a residential and commercial area in the city of Rio de Janeiro. This is, to our knowledge, the first published determination in Brazil, where both ethanol and ethanol-blended gasoline are used. Electro polished, stainless steel, evacuated canisters were used for sampling. The analysis was performed by gaschromatography with flame ionization detection (CG-FID) and by gas chromatography-mass spectrometry (CG-MS). A total of 80 and 56 compounds were determined in samples collected at the service station and control location, respectively. The most abundant compounds at the service station were in order of decreasing concentration (units: microg m(-3)): 2-methylbutane (1,715.7), 2-methylbut-1-ene (1,043.2), isobutene (758.8), 2-methylprop-1-ene (703.7), 2-methylpentane (492.1), pentadi-1,3-ene (189.7), toluene (157.0), benzene (144.5), but-2-ene (126.3) and m,p-xylene (123.2). A mean concentration of 144.5 microg m(-3) was determined for benzene, this value is about ten times the concentration determined in the control location in this work and about 70 times the value determined in other locations of Rio de Janeiro using charcoal cartridges for the sampling. The mean benzene/toluene ratios are 0.92 and 0.31 in the service station and control location, respectively. Since in Brazil service station workers are employed to fill customer's cars (self-service is not commonly used) the possible risk of cancer of these workers should be evaluated in a future study.

FY 2001 report on the results of the survey of the environmentally friendly type energy community project. Feasibility survey of the commercialization of the gasification melting system use heat supply business using container packing waste plastic and other waste as raw materials; 2001 nendo kankyo chowa gata energy komyuniti jigyo. Gaska yoyu system wo mochiita yoki hoso kei hai purasuchikku oyobi sonota no haikibutsu wo genryo to suru netsu kyokyu jigyo no jigyoka F/S chosa chosa hokokusho

Energy Technology Data Exchange (ETDEWEB)

NONE

2002-03-01

As to gasification melting facilities (Eco-Ene center) using container packing waste plastic and other waste as raw materials in 'the Eco-town Kochi City - Business Project,' study/evaluation of environmental conservation and business profitability were conducted. In Eco-Ene Center, power generation (power supply to users: 1,295 kW) and heat supply (27 GJ/h at maximum) are conducted using the gas product obtained from the combustion of waste. The environmental effect of introduction of Eco-Ene Center is as follows: energy conservation: 51,350-113,594 GJ/y, environmental pollution gas reduction: 1,128-4,987 t-CO2, 1,441-6,691 kg-NOx, 2,965-6,447 kg-SOx, 27,309 {mu}g-TEQ/m{sup 3} dioxin. As a result of the study of economical efficiency, the following was found out: In securing the ending cash balance such as personnel expenses, land lease cost and transportation cost, the subject is the acceptance price of container packing plastic from which a half of the profit can get, and it is necessary to receive subsidy for 1/2 of the price and reduce operating expenses. (NEDO)

Four new neolignans isolated from Eleutherococcus senticosus and their protein tyrosine phosphatase 1B inhibitory activity (PTP1B).

Science.gov (United States)

Zhang, Le; Li, Ban-Ban; Li, Hao-Ze; Meng, Xiao; Lin, Xin; Jiang, Yi-Yu; Ahn, Jong-Seog; Cui, Long

2017-09-01

Four new compounds, erythro-7'E-4-hydroxy-3,3'-dimethoxy-8,5'-oxyneoligna-7'-ene-7,9-diol-9'-al (1), (7S,8S)-4-hydroxy-3,1',3'-trimethoxy-4',7-epoxy-8,5'-neolign-9-ol (5), (7S,8S,7'E)-5-hydroxy-3,3'-dimethoxy-4',7-epoxy-8,5'-neolign-7'-ene-9,9'-diol (6) and (7S,8S,7'E)-5-hydroxy-3,3',9'-trimethoxy-4'-7-epoxy-8,5'-neolign-7'-ene-9-ol (7). Along with four known compounds (2-4, 8) were isolated from the EtOAc-soluble extract of Eleutherococcus senticosus. Their structures were elucidated on the basis of spectroscopic and physicochemical analyses. All the compounds were evaluated for in vitro inhibitory activity against PTP1B, VHR and PP1. Among them, compounds 1-4 and 6-8 were found to exhibit selective inhibitory activity on PTP1B with IC 50 values ranging from 17.2±1.6 to 32.7±1.2μM. Copyright © 2017 Elsevier B.V. All rights reserved.

Androgen and Progesterone Receptors Are Targets for Bisphenol A (BPA, 4-Methyl-2,4-bis-(P-HydroxyphenylPent-1-Ene--A Potent Metabolite of BPA, and 4-Tert-Octylphenol: A Computational Insight.

Directory of Open Access Journals (Sweden)

Mohd Rehan

Full Text Available Exposure to toxic industrial chemicals that have capacity to disrupt the endocrine system, also known as endocrine disrupting chemicals (EDCs, has been increasingly associated with reproductive problems in human population. Bisphenol A (BPA; 4,4'-(propane-2,2-diyldiphenol and 4-tert-octylphenol (OP; 4-(1,1,3,3-tetramethylbutylphenol are among the most common environmental contaminants possessing endocrine disruption properties and are present in plastics, epoxy resins, detergents and other commercial products of common personal and industrial use. A metabolite of BPA, 4-Methyl-2,4-bis(4-hydroxyphenylpent-1-ene (MBP is about 1000 times more biologically active compared to BPA. Epidemiological, clinical, and experimental studies have shown association of BPA and OP with adverse effects on male and female reproductive system in human and animals. The endocrine disruption activity can occur through multiple pathways including binding to steroid receptors. Androgen receptor (AR and progesterone receptor (PR are critical for reproductive tract growth and function. Structural binding characterization of BPA, MBP, and OP with AR and PR using molecular docking simulation approaches revealed novel interactions of BPA with PR, and MBP and OP with AR and PR. For BPA, MBP, and OP, five AR interacting residues Leu-701, Leu-704, Asn-705, Met-742, and Phe-764 overlapped with those of native AR ligand testosterone, and four PR interacting residues Leu-715, Leu-718, Met-756, and Met-759 overlapped with those of PR co-complex ligand, norethindrone. For both the receptors the binding strength of MBP was maximum among the three compounds. Thus, these compounds have the potential to block or interfere in the binding of the endogenous native AR and PR ligands and, hence, resulting in dysfunction. The knowledge of the key interactions and the important amino-acid residues also allows better prediction of potential of xenobiotic molecules for disrupting AR- and PR

Skønhed og rædsel i den nye Pharma Science Building

DEFF Research Database (Denmark)

Reeh, Henrik

2016-01-01

Reportage fra et fælles besøg i den nyligt indviede PharmaScience Building, Københavns Universitet, juni 2016. Teksten om mødet mellem journalist og forsker på den ene side og bygningen og dens brugere på den anden side. Journalist Christoffer Zieler henviser til Henrik Reehs separat offentliggjo......Reportage fra et fælles besøg i den nyligt indviede PharmaScience Building, Københavns Universitet, juni 2016. Teksten om mødet mellem journalist og forsker på den ene side og bygningen og dens brugere på den anden side. Journalist Christoffer Zieler henviser til Henrik Reehs separat...

Lipid constituents of the red alga Acantophora spicifera

Digital Repository Service at National Institute of Oceanography (India)

Wahidullah, S.; DeSouza, L.; Govenkar, M.B.

to report another novel steroid cholest-4-ene-3:~, 6/3- diol (4), cholest-4-ene-3-one (1), lauric acid or dode- canoic acid (3) and o-phthalic acid bis-(2 ethyl nonyl)- ester (2). RESULTS AND DISCUSSIONS Compound 1 had tH NMR (CDC13) spectrum....p. 46 C and the formula of Ct2H2402 was assigned on the basis of its mass spectrum which showed peaks at m/z 183 (M+-I7) and m/z 155 (M+-45) with a weak molecular ion peak at m/z 200. The ~ H NM R spectrum 200 MHz (CDC13) showed a triplet at 6 0.9 (3...

Obveznopravni odnosi u prijevozu živih životinja morem

Directory of Open Access Journals (Sweden)

Ivo Grabovac

2006-08-01

Full Text Available Prijevoz živih životinja morem spada u tzv. posebne prijevoze. Žive životinje su tijekom prijevoza izložene posebnim, samo njima kao živim bićima svojstvenim rizicima. Mjerodavne međunarodne konvencije i domaći propisi imaju neka posebna rješenja u prijevozu ove vrste robe, kojima je zapravo svrha omogućiti pogodniji pravni položaj prijevoznika. Autor u ovom radu ističe određene osobitosti u sadržaju prava i obveza ugovaratelja iz prijevoza živih životinja morem, a na temelju međunarodnih konvencija i nacionalnih propisa, osobito Pomorskog zakonika Republike Hrvatske.

Paper Library = Paper Library / Tomomi Hayashi ; kommenteerinud Una Meiberga

Index Scriptorium Estoniae

Hayashi, Tomomi, 1971-

2015-01-01

Tomomi Hayashi (HG Arhitektuur) paberist väliinstallatsioon Riias toimunud paberobjektide festivalil. Raamatukogu fassaad ümbritseti volditud valge papiga. Lühidalt Tomomi Hayashist ja büroost HG Arhitektuur

Keisri madrusest impeeriumi esivedurijuhiks / Lui Pikkov ; kommenteerinud Hans Treimann

Index Scriptorium Estoniae

Pikkov, Lui, 1935-2008

2009-01-01

Lui Pikkov oma onust Otto Piksarist (Pikkov), kes sündis Raplamaal Saunakülas, oli madruseks Nikolai II jahtlaeval Poljarnaja Zvezda, töötas vedurijuhina Eestis, oli Eesti NSV Ülemnõukogu saadik

GDA sinu abimees pakendil / Piret Jaaks ; kommenteerinud Elena Burm

Index Scriptorium Estoniae

Jaaks, Piret, 1980-

2010-01-01

Euroopa Komisjoni kokku kutsutud toitumisteadlaste komisjoni Eurodiet poolt koostatud GDA toitumisjuhist toiduainepakenditel, mis aitab jälgida toote- või joogiportsjoni osatähtsust päevasest soovitatavast kalorite ning olulisemate toitainete kogusest

Seadusega garanteeritud rahajõgi / Koit Brinkmann ; kommenteerinud Heido Vitsur

Index Scriptorium Estoniae

Brinkmann, Koit

2010-01-01

Elering prognoosib, et sel aastal maksab tõhusa koostootmise ja taastuvenergia toetusteks ligi miljard krooni. Tuulejaamadest suuremad toetused lähevad koostootmisjaamadele. Tuuleparkide rajaja OÜ Nelja Energia on saanud kahe töös oleva tuulepargi peale kokku 150 mln. krooni puhaskasumit, sellest 24,3 mln. krooni määrati omanikele dividendideks. Lisa: Kiire ja korraliku lobitöö musternäide

Kohtuveskid jahvatavad / Kaija Uuskam; kommenteerinud Maario Laas, Ute Wohlrab

Index Scriptorium Estoniae

2014-01-01

Eesti Hobusekasvatajate Seltsi ja Vana-Tori Hobuse Ühingu vahelisest kohtuvaidlusest tori hobuse tõuraamatu pidamise õiguste üle. Veterinaar ja Toiduameti seisukohti antud küsimuses tutvustab Veterinaar- ja Toiduameti põllumajandusloomade aretuse ja turukorralduse osakonna juhataja Kaija Uuskam

Valge villa / Karen Jagodin ; kommenteerinud Krista Aren, Emil Urbel

Index Scriptorium Estoniae

Jagodin, Karen, 1982-

2009-01-01

Villa (623 m² + kelder) Merirahu elamurajoonis Tallinnas. Arhitektid: Emil Urbel, Andrus Mark (AB Emil Urbel OÜ). Sisearhitektid: Krista Aren, Mati Veermets. Inseneriosad: AS Meistri Projekt. Haljastaja: Piret Kukk. Projekt: 2005-2008, valmis: 2009. Villa madalamat osa katab murtud pinnaga graniit, kõrgemat valge krohv

Eestlased läti kirjanduses / Contra ; kommenteerinud Hannes Korjus

Index Scriptorium Estoniae

Contra, pseud., 1974-

2011-01-01

Artikkel põhineb tõlkija ja ajakirjaniku Hannes Korjuse uurimustel ja käsitleb Gunars Janovskise, Märt Lapi (alias Mārtiņš Lapas), Augusts Deglavsi, Zigmunds Skujiņši, Auseklise (Miķelis Krogzemis) loomingut

Jutustamine kui kunst / Tuula Hyyrö ; kommenteerinud Meeli Pandis

Index Scriptorium Estoniae

Hyyrö, Tuula

2009-01-01

Suulised rahvatraditsioonid ei ole tänapäevalgi oma tähtsust minetanud, vaid on muutunud kunstiharuks, mida saab ülikoolis valikainena õppida. Juttude jutustamisest, muinasjuttude rääkimisest. Kommenteerib Eesti Lugemisühingu juhatuse liige Meeli Pandis

Kuressaare 2008. aasta parimad ehitised selgunud / kommenteerinud Hannes Koppel

Index Scriptorium Estoniae

2009-01-01

Parim terviklahendus golfiala (golfiväljaku projekteerija soome arhitekt Lassi Pekka Tilander, klubihoone projekteeris arhitektuuristuudio Siim & Kreis arhitekt Andres Siim). Parim uusehitis eramu Merikotka 45 (projekteerija Ösel Plan arhitekt Terje Truumaa) ja parim renoveeritud ehitis vana pritsumaja (Kuressaare Kommunaalprojekt projekteerija Galina Kanemägi)

Prague quadrennial 14.06-20.06/2007. Short play: crisis of forties flood after rain/ Vladimir Anshon

Index Scriptorium Estoniae

Anšon, Vladimir, 1963-

2010-01-01

XI rahvusvahelisest Praha lavastuskunstnike kvadriennaalist (Prague Quadrennial). Eesti rahvuslikust väljapanekust, kuraator Ene-Liis Semper ja Eesti Kunstiakadeemia väljapanekust, kuraator Lilja Blumenfeld

Agenda kultuuripealinna ArtGendast / Reet Varblane

Index Scriptorium Estoniae

Varblane, Reet, 1952-

1998-01-01

24. maini Stockholmi Kulturhusetis avatud Balti mere maade noortebiennaalist 'ArtGenda'. Peakorraldaja Beate Sydhoff. Eestlaste - Ene-Liis Semper, Martin Pedanik, Andrus Kõresaar, Marko Laimre - esinemisest.

Metabolism of 19-methyl-substituted steroids by human placental aromatase

International Nuclear Information System (INIS)

Beusen, D.D.; Carrell, H.L.; Covey, D.F.

1987-01-01

The 19-methyl analogues of androstenedione and its aromatization intermediates (19-hydroxyandrostenedione and 19-oxoandrostenedione) were evaluated as substrates of microsomal aromatase in order to determine the effect of a 19-alkyl substituent on the enzyme's regiospecificity. Neither the androstenedione analog [10-ethylestr-4-ene-3,17-dione (1c) nor the 19-oxoandrostenedione analog [10-acetylestr-4-ene-3,17-dione (3c)] was converted to estrogens or oxygenated metabolites by placental microsomes. In contrast, both analogues of 19-hydroxyandrostenedione [10-[(1S)-1-hydroxyethyl] extr-4-ene-3,17-dione (2c) and 10-[(1R)-1-hydroxyethyl]estr-4-ene-3,17-dione (2e)] were converted to the intermediate analog 3c in a process requiring O 2 and either NADH or NADPH. No change in enzyme regiospecificity was detected. The absolute configuration of 2e was determined by X-ray crystallography. Experiments with 18 O 2 established that 3c generated from 2c retained little 18 O ( 18 O (≅ 70%). All four 19-methyl steroids elicited type I difference spectra from placental microsomes in addition to acting as competitive inhibitors of aromatase. Pretreatment of microsomes with 4-hydroxyandrostenedione (a suicide inactivator of aromatase) abolished the metabolism of 2c and 2e to 3c, as well as the type I difference spectrum elicited by 2c and 2e. The failure of 2c, 2e, and 3c to undergo aromatization was rationalized in the context of a mechanistic proposal for the third oxygenation of aromatase requiring hydrogen abstraction at C 1 of 19,19-dihydroxyandrostenedione, homolytic cleavage of the C 10 -C 19 bond, and oxygen rebound at C 19

Aportaciones al conocimiento de la compresión tardía en la Cordillera Ibérica centro-oriental: la cuenca neógena inferior del Mijares (Teruel-Castellón

Directory of Open Access Journals (Sweden)

Paricio Cardona, J.

1986-10-01

Full Text Available The lower Neogene deposits of the Mijares valley (mainly fluvial facies are filling three paralell• grabens controlled by synsedimentary ENE normal faults. This structural pattern is created during a moderate compression phase with an ENE horizontal σ₁ axis which sometimes can be permuted with the vertical σ₂. Afterwards. a second SSE to S compression affects these deposits. The age of the basin can be established in the Upper Aragonian-Lower Vallesian bested on the Micromamal fauna found in two localities. Other sites in the cetral-oriental lberian Chain also show compressive deformations in well-dated deposits of Agenian and Aragonian ages. The compression still continues in this region during the Lower and Middle Miocene, the passage to the extension regime talking place in the Vanesian.

Las facies esencialmente fluviales que integran la unidad interior~ del valle medio del Mijares se depositan en tres grabens paralelos controlados por fallas sinsedimentarias ENE de componente normal. Este dispositivo estructural se crea en el curso de una etapa. compresiva de intensidad moderada, con un σ₁ según ENE, que eventualmente se intercambia con σ₂ vertical. Una segunda etapa de compresión SSE a S afecta posteriormente a esta unidad, datada en el Astaranciense-Vallesiense gracias a la fauna de micromamíferos proporcionada por dos yacimientos. Otras localidades de la Cadena Ibérica centro-oriental registran asimismo deformaciones compresivas en depósitos bien datados entre el Ageniense y el Aragoniense. Aunque sin producir apenas pliegues, el régimen compresivo perdura aún claramente en este sector de la cadena durante toda la primera mitad del Mioceno, siendo en el Vallesiense cuando se produce el tránsito definitivo a la distensión.

Jan Gehli teose "Linnad inimestele" ilmumine = Publication of an Estonian-language Edition of Jan Gehl's Cities for People / Yoko Alender, Liina Teder, Neeme Lopp

Index Scriptorium Estoniae

Alender, Yoko, 1979-

2016-01-01

Taani arhitektist Jan Gehlist ja tema raamatust "Linnad inimestele". Eestikeelse väljaande toimkond: Yoko Alender, Neeme Lopp, Liina Teder, Eneli Rohtla. Maastikuarhitektuuri aastapreemia nominent 2016

GORLİN - GOLTZ SENDROMU OLGU BİLDİRİSİ-GORLIN-GOLTZ SYNDROME (CASE REPORT)

OpenAIRE

Timoçin, Necla; Doğan, Özen

2013-01-01

ÖZETGorlin-Goltz sendromu, multipl çene kistleri, bazal hücreli tıevus, bazal hücreli karsînom, iskeletsel anomaliler ve bazı yumuşak doku lezyonlan ile karakterize bir hastalıktır. Sendromun bugüne kadar 40'a yakın bulguları bildirilmiştir. Bu makalede multipl çene kistleri ve tipik yüz görünümlerinden yola çıkılarak incelemeye alınıp,sendroma ait bazı iskeletsel anomalilerin saptanması üzerine Gor-Hn-Goltz Sendromu tanısı konan iki olgu bildirilmektedir.Anahtar sözcükler : Gorlin-Goltz...

PROUČAVANJE RECEPCIJE I POVIJEST ČITANJA (Premda se pojavljuje u 2016., ovaj rad – zapravo pisana verzija izlaganja održanog sredinom 2015. – predstavlja kronološki raniji stadij obrade teme kojom se opsežnije i po mnogo čemu drugačije bavi IX. poglavlje u međuvremenu objavljenoj knjizi David Šporer: Uvod u povijest knjige. Temelji pristupa (Leykam international, Zagreb, 2015.)

OpenAIRE

Šporer, David

2016-01-01

Članak nudi usporedbu povijesti čitanja i dosadašnjih modela proučavanja recepcije u književnosti, osobito njemačke „estetike recepcije“. Dok se, naime, u domaćim književnoznanstvenim krugovima o njemačkoj „estetici recepcije“ dosta znalo već početkom 1970-ih, to se ne može reći za povijest čitanja koja privlači sve više pažnje posljednjih desetljeća. U radu su zbog toga naznačene određene teme i perspektive karakteristične za povijest čitanja, koje bi mogle biti korisne i u proučavanju knjiž...

Spirocyclopropane-type sesquiterpene hydrocarbons from Schinus terebinthifolius Raddi.

Science.gov (United States)

Richter, Rita; von Reuss, Stephan H; König, Wilfried A

2010-08-01

The essential oil of Schinus terebinthifolius fruits was reinvestigated using GC and GC-MS techniques. Apart from several known compounds three sesquiterpene hydrocarbons with a carbon skeleton exhibiting the rare spiro(cyclopropane) moiety could be isolated by a combination of column chromatography and GLC. Structure assignments were carried out by NMR spectroscopy. These natural products are 9-spiro(cyclopropa)-4,4,8-trimethyl-2-methylenbicyclo[4.3.0]non-1(6)-ene (terebanene), 9-spiro(cyclopropa)-2,4,4,8-tetramethylbicyclo[4.3.0]nona-1,5-diene (teredenene), and (6R*,8R*)-9-spiro(cyclopropa)-2,4,4,8-tetramethylbicyclo[4.3.0]non-1-ene (terebinthene). Copyright 2010 Elsevier Ltd. All rights reserved.

Ostame maja! / Kersti Pikk, Aet Piel, Piret Tali

Index Scriptorium Estoniae

Pikk, Kersti

2007-01-01

Võrreldakse kolme eramut - Pirital, Viimsis (Arhitektuuriagentuur OÜ - arhitektid Inga Raukas, Toomas Tammis, Karli Luik ja Renee Puusepp) ja Harku vallas Vatslas. Lk. Oberhausi kinnisvaraspetsialisti Ene Arro kommentaar

Eesti keel eestlaste emotsioonidest / Haldur Õim

Index Scriptorium Estoniae

Õim, Haldur, 1942-

2004-01-01

Arvustus: Vainik, Ene. Lexical knowledge of emotions: the structure, variability and semantics of the Estonian emotion vocabulary. Tartu : Tartu University Press, 2004. (Dissertationes linguisticae Universitatis Tartuensis ; 5)

Statistical analysis of fragmentation patterns of electron ionization mass spectra of enolized-trimethylsilylated anabolic androgenic steroids

Science.gov (United States)

Fragkaki, A. G.; Angelis, Y. S.; Tsantili-Kakoulidou, A.; Koupparis, M.; Georgakopoulos, C.

2009-08-01

Anabolic androgenic steroids (AAS) are included in the List of prohibited substances of the World Anti-Doping Agency (WADA) as substances abused to enhance athletic performance. Gas chromatography coupled to mass spectrometry (GC-MS) plays an important role in doping control analyses identifying AAS as their enolized-trimethylsilyl (TMS)-derivatives using the electron ionization (EI) mode. This paper explores the suitability of complementary GC-MS mass spectra and statistical analysis (principal component analysis, PCA and partial least squares-discriminant analysis, PLS-DA) to differentiate AAS as a function of their structural and conformational features expressed by their fragment ions. The results obtained showed that the application of PCA yielded a classification among the AAS molecules which became more apparent after applying PLS-DA to the dataset. The application of PLS-DA yielded a clear separation among the AAS molecules which were, thus, classified as: 1-ene-3-keto, 3-hydroxyl with saturated A-ring, 1-ene-3-hydroxyl, 4-ene-3-keto, 1,4-diene-3-keto and 3-keto with saturated A-ring anabolic steroids. The study of this paper also presents structurally diagnostic fragment ions and dissociation routes providing evidence for the presence of unknown AAS or chemically modified molecules known as designer steroids.

PERSPECTIVAS CURRICULARES SOBRE A FORMAÇÃO DO PEDAGOGO PARA A EDUCAÇÃO NÃO ESCOLAR

Directory of Open Access Journals (Sweden)

José Leonardo Rolim de Lima Severo

2018-03-01

Full Text Available RESUMO: O artigo apresenta reflexões derivadas de um estudo curricular pautado pelo objetivo de mapear elementos demonstrativos do quadro atual de formação de pedagogos para atuação profissional em contextos de Educação Não Escolar (ENE. O estudo curricular abrangeu Projetos Pedagógicos de Cursos de Pedagogia de 20 universidades públicas brasileiras e os procedimentos analíticos se estruturaram a partir do uso da técnica de análise categorial de conteúdo. O referencial subjacente às análises baseia-se na discussão sobre o caráter epistemológico da Pedagogia e da ENE, bem como na abordagem crítica em torno dos enfoques curriculares que formam tradições do curso de Pedagogia no Brasil. Em vista dos resultados analíticos, se destacam a pouca expressividade de saberes específicos relativos à ENE na configuração curricular dos cursos de Pedagogia e, em consequência, os desafios da estruturação de percursos formativos que dialoguem melhor com demandas de novos âmbitos de inserção profissional do pedagogo.

Nora Särak: kõige suurem katsumus on iseenda usaldamine / intervjueerinud Katariina Rebane

Index Scriptorium Estoniae

Särak, Nora

2016-01-01

Kevadel Balti filmi- ja meediakooli magistriõppe lõpetanud Nora Säraku lõputööna valminud lühidokumentaalfilm "Valguseks/Valguseni/Valgusena" Petseris elavatest eestlastest pälvis Eesti Kultuurkapitali Audiovisuaalse kunsti sihtkapitali aastapreemia ning film valiti aasta dokumentaalfilmiks. Intervjuu Nora Särakuga

Tants ei küsi vanust / Ille Grün-Ots, Siiri Rebane

Index Scriptorium Estoniae

Grün-Ots, Ille, 1960-2016

2007-01-01

Kanal 2 menusaate "Tantsud tähtedega" järellainetuses vesteldakse artiklis seltskonnatantsust Revalia tantsukooli juhataja Merle Klandorfiga, bailatinost Dance Act direktori Georg Kodusaarega, kõhutantsust tantsuõpetaja Diana Otsinguga ja flamenkost Claudia Shevsthenkoga

Mae Hansen, girl who got herself a life / Mae Rebane ; intervjueerinud Kristina Traks

Index Scriptorium Estoniae

Hansen, Mae

2011-01-01

Ameerikas ärihariduse omandanud, pärast seda Eestis Sampo Pangas töötanud ja nüüd Taanis Danske Grupis töötav eestlanna oma tööst, töökorralduslikest erinevustest Eestis ja Taanis, eesmärkidest ja eraelust

Sadama ala planeering = Harbour area master plan / Ivan Sergejev, Helen Rebane, Karina Niinepuu

Index Scriptorium Estoniae

Sergejev, Ivan, 1987-

2010-01-01

EKA arhitektuuri ja linnaplaneerimise osakonna IV kursuse 2009-2010 õppeaastal erialase projekteerimise raames kavandatud planeeringu eesmärgiks on tihendada Tallinna sadama ala ning arendada sellest välja mitmekesine ja efektiivne linnaruum

2008. aastal keskenduti e-teenuste arendamisele : [2008. aasta rahvaraamatukogudes keskraamatukogude aruannete põhjal, tulevikuplaanides] / Meeli Veskus

Index Scriptorium Estoniae

Veskus, Meeli, 1953-

2009-01-01

Sisaldab ka: Raamatukogude kasutamine, lugejad ja kogud / Margit Jõgi. Lisa: Lugejateenindus ja kogud üldkasutatavates rahvaraamatukogudes 2008 : [joonised] / Margit Jõgi. Milline oli olukord rahvaraamatukogudes 2009. aasta algul? / Ene Riet.

Detailed Characterization of Nuclear Recoil Pulse Shape Discrimination in the DarkSide-50 Direct Dark Matter Experiment

Energy Technology Data Exchange (ETDEWEB)

Edkins, Erin Elisabeth [Univ. of Hawaii, Honolulu, HI (United States)

2017-05-01

While evidence of non-baryonic dark matter has been accumulating for decades, its exact nature continues to remain a mystery. Weakly Interacting Massive Particles (WIMPs) are a well motivated candidate which appear in certain extensions of the Standard Model, independently of dark matter theory. If such particles exist, they should occasionally interact with particles of normal matter, producing a signal which may be detected. The DarkSide-50 direct dark matter experiment aims to detect the energy of recoiling argon atoms due to the elastic scattering of postulated WIMPs. In order to make such a discovery, a clear understanding of both the background and signal region is essential. This understanding requires a careful study of the detector's response to radioactive sources, which in turn requires such sources may be safely introduced into or near the detector volume and reliably removed. The CALibration Insertaion System (CALIS) was designed and built for this purpose in a j oint effort between Fermi National Laboratory and the University of Hawaii. This work describes the design and testing of CALIS, its installation and commissioning at the Laboratori Nazionali del Gran Sasso (LNGS) and the multiple calibration campaigns which have successfully employed it. As nuclear recoils produced by WIMPs are indistinguishable from those produced by neutrons, radiogenic neutrons are both the most dangerous class of background and a vital calibration source for the study of the potential WIMP signal. Prior to the calibration of DarkSide-50 with radioactive neutron sources, the acceptance region was determined by the extrapolation of nuclear recoil data from a separate, dedicated experiment, ScENE, which measured the distribution of the pulse shape discrimination parameter, $f_{90}$, for nuclear recoils of known energies. This work demonstrates the validity of the extrapolation of ScENE values to DarkSide-50, by direct comparison of the $f_{90}$ distributio n of nuclear

Stolitsa baltiskoi modõ / Vladimir Stroi

Index Scriptorium Estoniae

Stroi, Vladimir

2005-01-01

Riias toimunud Balti moenädalast (Baltic Fashion Week) ja seal näidatud kollektsioonidest. Eestit esindasid Ene (?Evelin) Lill kollektsiooniga "Puudutus" ja Kätlin Kängsepp "Muudatuste uued tuuled"

Halonen arrives for State visit / Ella Karapetyan

Index Scriptorium Estoniae

Karapetyan, Ella

2010-01-01

Eestis riigivisiidil viibinud Soome president Tarja Halonen kohtus peaminister Andrus Ansipi ja Riigikogu spiikri Ene Ergmaga. Presidendiga visiidil kaasas olnud Soome haridusminister Henna Virkkunen kohtus haridus- ja teadusminister Tõnis Lukasega

ŽENE I SPORT U CRNOJ GORI

OpenAIRE

Cheryl Cooky; Marko Begović; Don Sabo; Carole Oglesby; Marj Snyder

2011-01-01

This paper is part of a larger study that identifies who plays sport in Montenegro, and the factors (family, education, economic, religious, cultural stereotypes, and so on) that contribute to girls and women’s participation in sport or that limit girls and women’s participation in sport. This study is the first evidencebased research assessing the current status of girls and women’s sport participation in Montenegro, at all institutional levels. Using mixed-methodologies (quantitative assess...

Ülikool ja haridus postajastul / Ene Grauberg

Index Scriptorium Estoniae

Grauberg, Ene, 1944-

2006-01-01

Informatsiooni kesksest rollist postindustriaalses ühiskonnas, ülikooli ja rakenduskõrgkooli teisenenud funktsioonidest, kõrghariduse uutest trendidest, õppejõu ja üliõpilase suhete muutumisest Pransuse filosoofi Jean-Francois Lyotardi interpreteeringuga

ŽENE I SPORT U CRNOJ GORI

Directory of Open Access Journals (Sweden)

Cheryl Cooky

2011-08-01

Full Text Available This paper is part of a larger study that identifies who plays sport in Montenegro, and the factors (family, education, economic, religious, cultural stereotypes, and so on that contribute to girls and women’s participation in sport or that limit girls and women’s participation in sport. This study is the first evidencebased research assessing the current status of girls and women’s sport participation in Montenegro, at all institutional levels. Using mixed-methodologies (quantitative assessment, survey data and qualitative focus group interviews this study will determine the numbers of girls and women participating in sport, as compared to boys and men in similar demographic categories, and to examine why girls and women do or do not participate in sport and what are their experiences in sport. Initial findings from the demographic assessment of sport in Montenegro illustrate overall gender disparities in sport participation in the 7 most popular sports; the majority of athletes, coaches, managers and decision-makers, medical staff, referees and sport delegates were men. We found the greatest gender imbalance in soccer and basketball, which were overwhelmingly male-dominated, and the greatest gender parity in handball and volleyball- and in some cases there were more female participants than male participants in these sports. We also examined overall trends in gender and sport participation across the different geographical regions, which were similar. However, there were differences in the types of sports men and women played in the different regions, which may indicate that some sports were more popular, or accepted, or easier to access for women in the central part of the country while other sports were more popular, or accepted or easier to access for women in the northern and southern regions. The project is a collaborative partnership with US- and Montenegro based scholars, the International Olympic Committee, the Montenegrin Olympic Committee, the United Nations Development Program, the Office for Gender Equality of the Ministry for Human and Minority Right of Montenegro, and NGO Inovativnost. Reflections and insights on multi-institutional partnerships in the study gender and sport participation will be offered.

Tööjuhendid loovuse arendajana / Ene Lind

Index Scriptorium Estoniae

Lind, Ene

2001-01-01

Loovuse arendamine tööõpetuse ja käsitöö tunnis. Katsest Tallinna koolide 2. ja 4. klasside õpilaste seas, milles katsetati kaht töö raskusastme ning kasutatavate materjalide ja töövahendite poolest erinevat tööjuhendit. Katse järel viidi läbi küsitlus, kus lapsed andsid hinnangu ja kommenteerisid tööjuhendi järgi iseseisvalt töötamist tööõpetuse tunnis

Eesti sugemetega jaapani aed / Ene Läkk

Index Scriptorium Estoniae

Läkk, Ene, 1957-

1999-01-01

Ülle Grishakovi kujundatud aed Kose-Lükatil Pirita jõe käärus endise prügimäe kohal. Kahe hektari suurusel alal on esindatud jaapani aed, dekoratiiv-tarbeaed, inglise stiilis vanaema aed. 7 illustratsiooni.

Lapse ülalpidamise hind / Ene-Margit Tiit

Index Scriptorium Estoniae

Tiit, Ene-Margit, 1934-

2005-01-01

Tutvustav artikkel sotsiaalministeeriumi tellimusel läbiviidud uuringust, mille eesmärgiks oli välja töötada lapse kõikidest vajadustest lähtuv ühtne metoodika lapse ülalpidamiskulude arvutamiseks ühes kuus. Tabelid. Diagrammid. Vt. ka lk. 15-16: Kaplan, Signe. Metoodika kasutamisvõimalusi

Tuul väljal / Ene-Reet Soovik

Index Scriptorium Estoniae

Soovik, Ene-Reet

1997-01-01

Arvustus: Woolf, Virginia. Esseed/ inglise k. tlk. Malle Talvet, Jaak Rähesoo. Tallinn : Hortus Litterarum, 1997; Woolf, Virginia. Orlando : elulugu / inglise k. tlk. Riina Jesmin. Tallinn : Perioodika, 1997. (Loomingu Raamatukogu; 31-34)

Juugendit armastav 21. sajandi kodu / Ene Vool

Index Scriptorium Estoniae

Vool, Ene, 1948-

2006-01-01

Kaunisse ümbrusse ehitatud stiilne maja, mille projekteeris Margit Kõrts. Sisustus, valgustid ja mööbel on juugendstiilis ja Kadri Tarbe-Pärtelpoeg projekteeris sobiva trepivõre ning trafarettmaalingu tegi Ruth Tuvike, kopeerides Alphonse Maria Mucha seinamaalingut. Mirjam Peili kommentaar

Saarlased võitsid karaokevõistluse / Ene Kallas

Index Scriptorium Estoniae

Kallas, Ene

2009-01-01

15. veebruaril Tallinna restoranis Kännu Kõrts krooniti Annika Väälma ja Iivo Miil Eesti karaokekuningannaks ja -kuningaks, mõlemad saarlased osalevad ka 28. veebruaril Tallinnas Sokos Hotell Viru restoranis Merineitsi karaoke rahvusvahelisel võistulaulmisel "Finbaltic Karaoke King and Queen"

Maia Laul / Maia Laul ; interv. Ene Ammer

Index Scriptorium Estoniae

Laul, Maia, 1921-2009

1998-01-01

Maia Laul eriala omandamisest, õppejõududest. Lõpetas 1949. a. Tallinna Riikliku Tarbekunsti Instituudi. Alar Kotli käealusena "Estonia" teatri taastamisprojekti juures. Peeter Tarvase ja August Volbergiga ENSV paviljponi kujundamas Moskvas VDNHs. Töötamisest ARSis. Sisearhitektuur ja monumentaalkunst (koostöö Eva Jänesega). Esinemistest näitustel "Ruum ja vorm". Ühiskondlike hoonete sisekujundustest. Vanaturu apteek (klaasigraafika Tiit Jürna)

Põllumajandussaaduste turg : [1994-2003 Eestis] / Ene Maadvere

Index Scriptorium Estoniae

Maadvere, Ene, 1948-

2004-01-01

Ilmunud ka: Agriculture and rural development : overview 2003/2004. - Tallinn, 2004, lk. 124-132. Põllumajandussaaduste ekspordimaht vähenes 2003. a. eelmise aasta sama perioodiga võrreldes 0,4%, importmaht aga suurenes 7%. Tabelid. Diagrammid. Graafikud

Mida lugeja raamatukogult tegelikult ootab / Ene Riet

Index Scriptorium Estoniae

Riet, Ene, 1954-

2011-01-01

4. teadus- ja erialaraamatukogude päev toimus 21. oktoobril 2011 Eesti Muusika- ja Teatriakadeemias. Teadusraamatukogu aasta teo auhinna pälvis Urmas Sinisalu tulemusliku ja innovaatilise töö eest raamatukogude infosüsteemi ESTER arendamisel. Erialaraamatukogu aasta teo auhinna sai TÜ ajakirjanduse ja kommunikatsiooni instituudi raamatukoguhoidja Maio Vaniko raamatukogundust arendava tegevuse eest

Episteemilise loogika mõningad aspektid / Ene Grauberg

Index Scriptorium Estoniae

Grauberg, Ene, 1944-

2004-01-01

Episteemiline loogika on modaalse loogika alasüsteemi loogika teooria, mis kasutab episteemilise operaatoreid ...teab,et..., ...eeldab,et.... Tema aineks on neid operaatoreid sisaldavate otsustuste õige organiseerimise reeglid ja tingimused. Varem ilmunud: Metod modelirovanija i nekotorõje filosofskije problemõ istorii i metodologii jestestvoznanija. Tallinn, 1975.

Ainenõukogu tähelepanekuid / Ene Laanes

Index Scriptorium Estoniae

Laanes, Ene

2003-01-01

Üleriigiline kehalise kasvatuse ainenõukogu peab vajalikuks juhtida haridusametnike, koolijuhtide ja kooli omanike tähelepanu kehalise kasvatuse ainekava läbiviimisel üles kerkinud probleemidele: meditsiinilisse erigruppi kuuluvate õpilaste hindamine kehalise kasvatuse aines, kehalise kasvatuse tunniks vajalikud harjutuspaigad ja vahendid, nädalatundide arv

Cultural Trauma and Life Stories / Ene Kõresaar

Index Scriptorium Estoniae

Kõresaar, Ene

2007-01-01

Aili Aarelaid-Tarti 15-aastase uuringu tulemused raamatus "Cultural Trauma and Life Stories", Hesinki, Kikimora Publications, 2006. Uuritud on kolme suurt rahvusgruppi 1940-test tingitud trauma kontekstis: eestlased kodumaal, eestlased eksiilis ja venekeelne rahvusgrupp Eestis postsovetlikus diskursuses

Seadusemuudatused, mis teevad elu paremaks / Ene Kaups

Index Scriptorium Estoniae

Kaups, Ene, 1963-

2008-01-01

2008. aastal jõustuvatest seadusemuudatustest. Ilmunud ka Koit 7. veeb. 2008, lk. 6 ; Lääne Elu 7. veeb. 2008, lk. 2 ; Hiiu Leht 8. veeb. 2008, lk. 2 ; Järva Teataja 9. veeb. 2008, lk. 2 ; Türi Rahvaleht 8. veeb. 2008, lk. 4, pealkiri kujul: Seadusemuudatustest ; Meie Maa 15. veeb. 2008, lk. 2 ; Sakala 15. veeb. 2008, lk. 2, pealkiri kujul: Käesolev aasta toob hulga olulisi muudatusi ; Sõnumitooja 27. veeb. 2008, lk. 2 ; Valgamaalane 26. veeb. 2008, lk. 2

16,17-Seco- and 2,3:16,17-di-seco-pregnanes from Guarea guidonia

Energy Technology Data Exchange (ETDEWEB)

Garcez, Walmir Silvan; Garcez, Fernanda Rodrigues [Universidade Federal de Mato Grosso do Sul (UFMS), Campo Grande, MS (Brazil). Dept. de Quimica]. E-mail: wgarcez@nin.ufms.br; Soares, Luzinatia Ramos [Universidade Federal de Mato Grosso do Sul (UFMS), Campo Grande, MS (Brazil). Dept. de Quimica; Universidade Estadual de Mato Grosso do Sul, Campo Grande, MS (Brazil)

2008-07-01

Two new seco- and di-seco-pregnanes, 2{alpha},3{beta}-dihydroxy-16,17-seco-pregn-17-ene-16-oic acid methyl ester 2{beta},19-hemiketal (1) and 2,3:16,17-di-seco-pregn-17-ene-3-oic acid-16-oic acid methyl ester-19-hydroxy-2-carboxylic acid-2,19-lactone (2), have been obtained from the trunk bark of Guarea guidonia. Their structures have been established by a combination of 1D- and 2D-NMR spectroscopic techniques and MS data. The unique seco- and di-seco-pregnane carbocyclic skeletal types as found in compounds 1 and 2 are being reported in the Meliaceae for the first time as well as the occurrence of pregnanes in the genus Guarea. (author)

New steroidal glycosides from Tribulus terrestris L.

Science.gov (United States)

Chen, Gang; Liu, Tao; Lu, Xuan; Wang, Hai-Feng; Hua, Hui-Ming; Pei, Yue-Hu

2012-01-01

Two new steroidal glycosides were isolated from Tribulus terrestris L. Their structures were elucidated as 26-O-β-D-glucopyranosyl-5α-furostan-12-one-20(22)-ene-3β,23,26-triol-3-O-β-D-xylopyranosyl-(1 → 2)-[β-D-xylopyranosyl-(1 → 3)]-β-D-glucopyranosyl-(1 → 4)-[α-L-rhamnopyranosyl-(1 → 2)]-β-D-galactopyranoside (1) and 26-O-β-D-glucopyranosyl-5α-furostan-20(22)-ene-3β,23,26-triol-3-O-β-D-xylopyranosyl-(1 → 2)-[β-D-xylopyranosyl-(1 → 3)]-β-D-glucopyranosyl-(1 → 4)-[α-L-rhamnopyranosyl-(1 → 2)]-β-D-galactopyranoside (2) by spectroscopic methods including 1D and 2D NMR experiments.

Experimental and computational evaluation of area selectively immobilized horseradish peroxidase in a microfluidic device

DEFF Research Database (Denmark)

Hoffmann, Christian; Pereira Rosinha Grundtvig, Ines; Thrane, Joachim

2017-01-01

experimentally and by computational fluid dynamics (CFD) simulations. Ultimately, such a correlation would lead to faster development through computational pre-screening and optimized experimental design.In this proof-of-concept study, microreactors were prepared in a 2-step curing process of an off......-stoichiometric thiol-ene-epoxy (OSTE+) mixture employing both a thiol-ene (TEC) and a thiol-epoxy curing reaction. Subsequent surface functionalization of the remaining thiol groups on the reactor surface through stenciled photoinitiated TEC enabled the preparation of specific surface patterns in the reactor. Patterns...... as obtained from experimental determination. This good agreement between the obtained experimental and computational results confirmed the high potential of CFD models for predicting and optimizing the biocatalytic performance of such a reactor....

Estraadi comeback. Ojasoo - Semperi "Nafta!" kui XXI sajandi estraadilavastus / Ott Karulin

Index Scriptorium Estoniae

Karulin, Ott, 1980-

2006-01-01

Estraadi sugemetega etendustest ja estraaditeatrist Eestis. Pikemalt peatutakse Ene-Liis Semperi ja Tiit Ojasoo lavastustel "Nafta", "No More Tears", "Julia" (aut. W. Shakespeare - T. Ojasoo) ja "Kuningas Ubu" (aut. A. Jarry)

Vaata inimest. Näe elu / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2011-01-01

Teater NO99 lavastusest "The Rise and Fall of Estonia" Nokia Kontserdimajas. Idee, kontseptsioon ja lavastus Tiit Ojasoo ja Ene-Liis Semper. Viktor Pelevini "Kollane nool" Ugala teatris, lavastaja Mart Koldits

Raamatututvustus: lugemine kui mäng / Külliki Kask

Index Scriptorium Estoniae

Kask, Külliki, 1949-

2009-01-01

Tutvustus: Eco, Umberto. Kuus jalutuskäiku kirjandusmetsades / inglise keelest tõlkinud Ene-Reet Soovik. Tallinn : Varrak, 2009 ; Martin, George R. R. Windhaven / tõlkinud Jaana Talja. [Tartu] : Fantaasia, c2009

Pariis kui uus peatus inimese teekonnal / Katre Talviste

Index Scriptorium Estoniae

Talviste, Katre

2003-01-01

Karl Ristikivi "Inimese teekonna" tõlkest prantsuse keelde ("Chemin terrestre", tõlkija Tarah Montbélialtz, pseud, kirj. La Guillotine, Pariis, 2002). Ka Claude Merlini ja Ene Rämmeldi lavastusest "Inimese teekond"

Hoolimisega uimastite vastu

Index Scriptorium Estoniae

2011-01-01

Vilniuses 15. aprillil 2011 toimunud heategevuskontserdist ja oksjonist rahvusvahelise uimastivastase ennetustööga tegeleva sihtasutuse Mentor Foundation toetuseks. Enampakkumisele pandi ka president Toomas Hendrik Ilvese ja Riigikogu spiikri Ene Ergma kirjutusvahendid

Otsustava teo päev / Tiit Maksim

Index Scriptorium Estoniae

Maksim, Tiit, 1941-

2005-01-01

Tallinnas Harjumäe nõlval avati Vabaduse monumendi alge - Võrumaalt Urvaste vallast toodud põllukivi, millesse on raiutud "Siia rajatakse vabaduse monument. 29. X 2005", osales ka parlamendiliige, spiiker Ene Ergma

Alleviation of osmotic stress of water and salt in germination and ...

African Journals Online (AJOL)

STORAGESEVER

2008-07-04

Jul 4, 2008 ... ening, osmoconditioning, osmohardening, and hormonal priming have ... germination, emergence and plant growth of wheat (Das and Choudhury .... In the present study, a significant three way interaction. (osmotic agents ...

Kunstiteaduslik doktoritöö EKA-s kaitstud / Ingrid Ruudi

Index Scriptorium Estoniae

Ruudi, Ingrid

2005-01-01

Heie Treier "Kohalik modernsus kunstis. Eesti varamodernistliku kunsti teoreetiline ja ajalooline kontseptualiseerimine ning Karl Pärsimägi paradigmaleidmise perioodil". Juhendaja Thomas McEvilley, eelretsensent Katrin Kivimaa ja Ene Lamp. Oponent Jaak Kangilaski

Extra Strong Super Light / Magdalena Lewoc

Index Scriptorium Estoniae

Lewoc, Magdalena

2003-01-01

2003. a. Szczecini Rahvusmuuseumis toimunud 5. rahvusvahelisest kunstinäitusest võtsid osa poola, saksa, rootsi, soome, leedu, läti, ukraina ja eesti kunstnikud. Pikemalt Ene-Liis Semperi ja Jaan Toomiku loomingust

Reference: 84 [Arabidopsis Phenome Database[Archive

Lifescience Database Archive (English)

Full Text Available enes in developing anthers was confirmed by RT-PCR and was consistent with a male... of an HMA2-green fluorescent protein fusion by confocal microscopy. These observations are consistent

Peaminister Juhan Parts ei plaani ametit maha panna / Juhan Parts ; interv. Toomas Sildam

Index Scriptorium Estoniae

Parts, Juhan, 1966-

2004-01-01

Peaminister Juhan Parts pooldab paremerakondade ühinemist, ei kavatse ametist lahkuda ning peab valitsuse üheks ülesandeks rahvaarutelu algatamist vabaduse samba üle. Lisa: Ene Ergma kõnest Riigikogus (13.09.2004)

The influence of matrix properties on growth and morphogenesis of human pancreatic ductal epithelial cells in 3D

Science.gov (United States)

Raza, Asad; Ki, Chang Seok; Lin, Chien-Chi

2013-01-01

A highly tunable synthetic biomimetic hydrogel platform was developed to study the growth and morphogenesis of pancreatic ductal epithelial cells (PDEC) under the influence of a myriad of instructive cues. A PDEC line, PANC-1, was used as a model system to illustrate the importance of matrix compositions on cell fate determination. PANC-1 is an immortalized ductal epithelial cell line widely used in the study of pancreatic tumor cell behaviors. PANC-1 cells are also increasingly explored as a potential cell source for endocrine differentiation. Thus far, most studies related to PANC-1, among other PDEC lines, are performed on 2D culture surfaces. Here, we evaluated the effect of matrix compositions on PANC-1 cell growth and morphogenesis in 3D. Specifically, PANC-1 cells were encapsulated in PEG-based hydrogels prepared by step-growth thiol-ene photopolymerization. It was found that thiol-ene hydrogels provided a cytocompatible environment for encapsulation and 3D culture of PANC-1 cells. In contrast to a monolayer morphology on 2D culture surfaces, PANC-1 cells formed clusters in 3D thiol-ene hydrogels within 4 days of culture. After culturing for 10 days, however, the growth and structures of these clusters were significantly impacted by gel matrix properties, including sensitivity of the matrix to proteases, stiffness of the matrix, and ECM-mimetic motifs. The use of matrix metalloproteinase (MMP) sensitive linker or the immobilization of fibronectin-derived RGDS ligand in the matrix promoted PANC-1 cell growth and encouraged them to adopt ductal cyst-like structures. On the other hand, the encapsulated cells formed smaller and more compact aggregates in non-MMP responsive gels. The incorporation of laminin-derived YIGSR peptide did not enhance cell growth and caused the cells to form compact aggregates. Immobilized YIGSR also enhanced the expression of epithelial cell markers including β-catenin and E-cadherin. These studies have established PEG

Evolutional neurologic evaluation of seven year-old children born prematurely Avaliação neurológica evolutiva aos sete anos de idade de crianças nascidas prematuras

Directory of Open Access Journals (Sweden)

Lygia Ohiweiler

1996-09-01

Full Text Available A sample of 51 children aged 7 with a history of prematurity was compared to 44 age-matched children who were born at term at the HCPA. The premature children had had gestational ages up to 37 weeks and 6 days and were born weighing less than 2500g. The control group consisted of children born with gestational age between 38 and 42 weeks and weights above 2S00g. The evaluation criteria were clinical examination, neurological examination and the evolutional neurological evaluation (ENE. The results pointed out that impulsiveness, aggressiveness, disorganization and enuresis were prevalent symptoms of developmental disturbances in the sample of prematures. Alterations at neurological examination did not discriminate between the two groups, although cerebral palsy occurred only in the proup of prematures. The ENE functions which differentiated the two groups studied were dynamic balance, appendicular and trunk-limb coordination and motor persistence.Para estudar o desenvolvimento neuropsicomotor em amostra de prematuros aos 7 anos de idade, foram avaliadas 51 crianças prematuras e comparadas com 44 a termo. O grupo de prematuros tinha idade gestacional de até 37 semanas e 6 dias e peso de nascimento até 2500g. O grupo controle foi constituído de crianças com idade gestacional entre 38 e 42 semanas e acima de 2500g. Os instrumentos de avaliação utilizados foram os exames clinico, neurológico e neurológico evolutivo (ENE. Os resultados mostraram que impulsividade, agressividade, desorganização e enurese foram sintomas prevalentes nos prematuros. As alterações no exame neurológico não discriminaram os grupos, embora paralisia cerebral só tenha ocorrido nos prematuros. As funções do ENE que distinguiram os grupos foram equilíbrio dinâmico, coordenação tronco-membros e persistência motora, constituindo-se esta no comprometimento dominante nos prematuros e as alterações na coordenação tronco-membros em achado peculiar neste

Energia avastuskeskus = Energy discovery center / Margit Aule ; kommenteerinud Kristiina Raid

Index Scriptorium Estoniae

Aule, Margit, 1981-

2015-01-01

Energia avastuskeskuse (Põhja pst 29/31, Tallinn) interjöörist ja ekspositsiooni kujundusest. Autor Margit Argus (KAOS Arhitektid); ekspositsiooni kujundus Margit Argus, Margit Aule; arhitektid Sander Aas, Margit Aule, Pelle Sten Viiburg (KAOS Arhitektid). Eesti Sisearhitektide Liidu aastapreemia 2014/2015 parima ajaloolise interjööri eest

Eisma sadamahoone = Eisma port building / Mari Kurismaa ; kommenteerinud Krista Aren

Index Scriptorium Estoniae

Kurismaa, Mari, 1956-

2015-01-01

Eluruumid Eisma sadamahoones (Eisma küla, Vihula vald, Lääne-Virumaa). Sisekujunduse autorid Mari Kurismaa, Indrek Allmann; arhitekt Indrek Allmann (AB Pluss). Eesti Sisearhitektide Liidu aastapreemia 2014/2015 parima kodu eest. Lühidalt Mari Kurismaast ja Indrek Allmannist

Pantvangide pered loodavad valitsuse pingutustele / Anneli Ammas ; kommenteerinud Alan Fraser

Index Scriptorium Estoniae

Ammas, Anneli, 1962-

2011-01-01

Liibanonis röövitud eestlaste lähedaste kommentaare pantvangide uue videopöördumise kohta. President Toomas Hendrik Ilves algatas pantvangide toetuseks kollase lindi kandmise kampaania. Vt. ka juhtkiri lk. 2: Lootuse lindid

Saaremaalt saab heinaseemet igale maitsele / Jana Rand ; kommenteerinud Hindrek Older

Index Scriptorium Estoniae

Rand, Jana, 1963-

2016-01-01

Saaremaal Laadjala külas tegutsev OÜ Saaremaa Seeme on Eesti suurim heinaseemne kasvataja, aga mitte erakordselt head looduslikud tingimused pole ettevõtte edu taganud, vaid aastakümnetega omandatud kogemused ja terve Sauna pere pühendunud töö. Vestlusest Arli Saunaga

Maagiline Matrix - muutuste võti / Marika Makarova ; kommenteerinud Ainar Leppik

Index Scriptorium Estoniae

Makarova, Marika

2010-01-01

USA kiropraktiku Richard Bartletti loodud Matrix Energetics tehnikate alusl Ainar Leppiku poolt loodud Maagilise Maatriksi meetodist, mis õpetab muutuste toomist oma ellu. Vestlustest Maagilise Maatriksi õpetajatega

Ärikultuur 15 aastat tagasi / Urve Vilk ; kommenteerinud Aku Sorainen

Index Scriptorium Estoniae

Vilk, Urve

2011-01-01

Krediidipanga juhatuse esimehe Andrus Kluge hinnangul oli ärikeskkond Eestis 15 aastat tagasi mitteformaalsem, naiivsem ja spontaansem kui praegu, kõik tegelesid kõigega. Margus Alviste hinnangul on 15 aastaga muutunud tavad ja kombed, rohkem on variserlikkust, eestlaste ettevõtlikkus on vähenenud

Õigusabi vähekindlustatuile / Mari Kasela ; kommenteerinud Maire Arm

Index Scriptorium Estoniae

Kasela, Mari

2011-01-01

Tasuta õigusabi majandus- ja makseraskustesse sattunud peredele pakub Eesti Juristide Liidu õigusportaal, esmase õigusabi teenust pakuvad Eesti Juristide Liit, sihtasutus Õigusteenuste Büroo Tallinnas, Üliõpilaste Õigusbüroo Tallinnas, Eesti Advokatuuri ja Lastekaitse Liidu koostööprojekt "Hea nõu lastega peredele"

Vaprad lucky loser'id / Jüri Aarma ; kommenteerinud Tanja Muravskaja

Index Scriptorium Estoniae

Aarma, Jüri, 1951-

2009-01-01

Tanja Muravskaja isikunäitus "Lucky Losers" Tallinna Linnagaleriis. Eksponeeritud videoportreed vene rahvusest Eesti kodanikest Dimitri Klenskist, Adolf Käisist, Anna Levandist, Tatjana Muravjovast, Mihhail Stalnuhhinist, Eduard Tomanist ja Boris Tuchist

Klaasis on pinget / Reet Varblane ; kommenteerinud Kati Kerstna, Kairi Orgusaar

Index Scriptorium Estoniae

Varblane, Reet, 1952-

2009-01-01

Klaasi kui (kunsti)materjali kasutamisest, mitmete erialade sümbioosist. Laura Mattioli Rossi, Rosa Barovier Mentasti ja Adriano Berengo kureeritud näitusest "Glass Stress" ("Klaasipinge") tänavusel Veneetsia biennaalil. Eesti klaasikunstist, Kai Koppeli eestvedamisel toimunud Haapsalu klaasipäevadest "Kasuta päeva"

LHV kinnitab Soome laenuturul kanda / Silvia Kruusmaa ; kommenteerinud Raul Malmstein

Index Scriptorium Estoniae

Kruusmaa, Silvia

2010-01-01

LHV sai Soome finantsinspektsioonilt loa hakata osutama piiriüleseid teenuseid Soomes, pank sõlmis Luottotalo Fenno Oy-ga laenuportfelli ostulepingu, omandades ligikaudu 12 500 eraisiku laenulepingud

Uut Kristjan Palusalu põgenemisloos / Kristjan Palusalu ; kommenteerinud Paavo Kivine

Index Scriptorium Estoniae

Palusalu, Kristjan, 1908-1987

2015-01-01

Palusalu ülekuulamisprotokoll. Protokollis on juttu Eesti oludest bolševiseerimise aegadel, metsavennasalkadest, mobiliseerimisest, teekonnast läbi Põhja-Venemaa, nn troika kohtust, bolševike-aegsetest vanglaoludest, rahva meelsusest bolševike võimu ajal, spordioludest

Kolmanda aastatuhande piraadid / kommenteerinud Peter Chalk ja Gordan Van Hook

Index Scriptorium Estoniae

2009-01-01

Piraatlusest Somaalia piirkonnas ja rahvusvahelistest dokumentidest piraatluse vastu võitlemiseks 21. sajandil. Kommenteerivad uurimiskeskuse RAND Corporation vanempoliitanalüütik Peter Chalk ja transpordikompanii Maersk Line innovatsiooni ja arenduse vanemdirektor Gordan Van Hook

Vahetuspere isa osutus seksuaalseks ahistajaks / Merje Pors ; kommenteerinud Oliver Kontram

Index Scriptorium Estoniae

Pors, Merje

2011-01-01

Vahetusõpilase ahistamise juhtumist Argentiinas, kus vahetuspere isa kuritarvitas seksuaalselt vahetusõpilast. Vahetusprogrammide kaudu välismaale õppima minejate arvu vähenemisest, mistõttu on programmid sunnitud ümber orienteeruma ja rohkem välisõpilasi Eestisse tooma

Suurõppus valmistas linlastele peavalu / Mari Mets ; kommenteerinud Margus Kotter

Index Scriptorium Estoniae

Mets, Mari

2011-01-01

17. mail toimus Tartus suur kriisiõppus EU CREMEX 2011, mille stsenaariumi järgi sattus õnnetusse ohtlikke kemikaale vedanud vagun ja tekkis radioaktiivsuse oht. Õppuse käigus evakueeriti ligi 500 Tähtvere elanikku

Reform andnuks kirevama riigikogu / Alo Raun ; kommenteerinud Martin Mölder

Index Scriptorium Estoniae

Raun, Alo, 1981-

2011-01-01

Juhul kui Riigikogu oleks kokku pandud üleriigiliste nimekirjadeta, oleks sinna pääsenud nelja asemel kuus erakonda, lisaks kaks üksikkandidaati, Reformierakonna ja IRLi koalitsioon oleks kahanenud 52 mandaadile

Nia - rõõm liikumisest / Monica Raud ; kommenteerinud Sirje Sinisoo

Index Scriptorium Estoniae

Raud, Monica, 1981-

2014-01-01

1983. aastal Debbie ja Carlos Rosaśide poolt üheksast liikumistehnikast - taekwondo, aikido, taiji, dšässtants, moderntants, Isadora Duncani tants, Feldenkraisi meetod, Aleksanderi tehnika ja jooga - sünteeritud liikumisõpetusest

Reference: 83 [Arabidopsis Phenome Database[Archive

Lifescience Database Archive (English)

Full Text Available ene cause hypersensitivity to exogenous ethylene and its precursor 1-aminocyclopr...ed EIN3 levels, even in the absence of exogenous ethylene. Collectively, our results show that the SCF(EBF1/

Naised, kes ei oska võidelda / Tiina Tauraite

Index Scriptorium Estoniae

Tauraite, Tiina, 1976-

2011-01-01

Toimetuse intervjuu näitleja Tiina Tauraitega Sulev Keeduse filmist "Kirjad Inglile" (Eesti-Soome 2011), stsenaristid Madis Kõiv ja Sulev Keedus, produtsent Kaie-Ene Rääk. Tiina Tauraite - arhivaar Edda osatäitja

Functional bio-based polyesters by enzymatic polymerization

DEFF Research Database (Denmark)

Daugaard, Anders Egede; Hoffmann, Christian; Andersen, Christian

During recent years enzymatic polymerization has become increasingly popular as an alternative to classical polyesterification processes. The high regioselectivity observed for lipases permits preparation of novel polyesters with a high number of functional groups.1 This is particularly interesting...... polymerization was applied to prepare functional water soluble polyesters based on dimethyl itaconate and poly(ethyleneglycol).2 The monomer permits postfunctionalization using thiol-ene chemistry or aza-michael additions, which was used to illustrate the possibilites of preparing functional hydrogels. Hydrogels...... based on the polyesters were shown to be degradable and could be prepared either from the pure polyester or from prefunctionalized polyesters, though the thiol-ene reactions were found to be less effective. Since then a new monomer, trans-2,5-dihydroxy-3-pentenoic acid methyl ester (DPM) has been...

Merosesquiterpene Congeners from the Australian Sponge Hyrtios digitatus as Potential Drug Leads for Atherosclerosis Disease

Directory of Open Access Journals (Sweden)

Huda A. Wahab

2016-12-01

Full Text Available A study of the chemical constituents from the Australian Sponge Hyrtios digitatus has provided a perspective on the connection between the chemistry and biology of the puupehenones, a unique and unusual class of merosesquiterpenes. In this study, a new tetracyclic merosesquiterpene, 19-methoxy-9,15-ene-puupehenol (1 was isolated from the marine sponge Hyrtios digitatus along with the known 20-methoxy-9,15-ene-puupehenol (2. Their structures were elucidated on the basis of spectroscopic data (1H and 13C NMR in combination with experimental electronic circular dichroism (ECD data. Compounds 1 and 2 are active at 1.78 μM and 3.05 μM, respectively, on Scavenger Receptor-Class B Type 1 HepG2 (SR-B1 HepG2 stable cell lines, targeting atherosclerosis disease.

Ester-free Thiol-X Resins: New Materials with Enhanced Mechanical Behavior and Solvent Resistance.

Science.gov (United States)

Podgórski, Maciej; Becka, Eftalda; Chatani, Shunsuke; Claudino, Mauro; Bowman, Christopher N

A series of thiol-Michael and radical thiol-ene network polymers were successfully prepared from ester-free as well as ester-containing monomer formulations. Polymerization reaction rates, dynamic mechanical analysis, and solvent resistance experiments were performed and compared between compositions with varied ester loading. The incorporation of ester-free alkyl thiol, vinyl sulfone and allylic monomers significantly improved the mechanical properties when compared with commercial, mercaptopropionate-based thiol-ene or thiol-Michael networks. For polymers with no hydrolytically degradable esters, glass transition temperatures (T g 's) as high as 100 °C were achieved. Importantly, solvent resistance tests demonstrated enhanced stability of ester-free formulations over PETMP-based polymers, especially in concentrated basic solutions. Kinetic analysis showed that glassy step-growth polymers are readily formed at ambient conditions with conversions reaching 80% and higher.

Detailed Characterization of Nuclear Recoil Pulse Shape Discrimination in the Darkside-50 Direct Dark Matter Experiment

Science.gov (United States)

Ludert, Erin Edkins

While evidence of non-baryonic dark matter has been accumulating for decades, its exact nature continues to remain a mystery. Weakly Interacting Massive Particles (WIMPs) are a well motivated candidate which appear in certain extensions of the Standard Model, independently of dark matter theory. If such particles exist, they should occasionally interact with particles of normal matter, producing a signal which may be detected. The DarkSide-50 direct dark matter experiment aims to detect the energy of recoiling argon atoms due to the elastic scattering of postulated WIMPs. In order to make such a discovery, a clear understanding of both the background and signal region is essential. This understanding requires a careful study of the detector's response to radioactive sources, which in turn requires such sources may be safely introduced into or near the detector volume and reliably removed. The CALibration Insertaion System (CALIS) was designed and built for this purpose in a joint effort between Fermi National Laboratory and the University of Hawaii. This work describes the design and testing of CALIS, its installation and commissioning at the Laboratori Nazionali del Gran Sasso (LNGS) and the multiple calibration campaigns which have successfully employed it. As nuclear recoils produced by WIMPs are indistinguishable from those produced by neutrons, radiogenic neutrons are both the most dangerous class of background and a vital calibration source for the study of the potential WIMP signal. Prior to the calibration of DarkSide-50 with radioactive neutron sources, the acceptance region was determined by the extrapolation of nuclear recoil data from a separate, dedicated experiment, ScENE, which measured the distribution of the pulse shape discrimination parameter, f 90, for nuclear recoils of known energies. This work demonstrates the validity of the extrapolation of ScENE values to DarkSide-50, by direct comparison of the f90 distribution of nuclear recoils from ScENE

Kak prodat "Babushku" / Maria Melnikova ; interv. Galina Balashova

Index Scriptorium Estoniae

Melnikova, Maria

2005-01-01

Eesti Vene saatkonna "Vene galerii" osalemisest Madridis kunstilaadal ARCO-2005. Galerii esitles Ene-Liis Semperi videofilmi "Nimetu" ja vene kunstnike Bogdan Mamonovi ning Anton Litvini töid. Semperi ja Mamonovi töödest

Experiment list: ERX144535 [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available ene piRNA promoters in mammals Organism=Mus musculus || Sex=male || OrganismPart=testis || StrainOrLine=C57B...,4.7,550 Illumina Genome Analyzer II sequencing; Ricochet transcription of pachyt

Experiment list: ERX144534 [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available ene piRNA promoters in mammals Organism=Mus musculus || Sex=male || OrganismPart=testis || StrainOrLine=C57B...,9.7,783 Illumina Genome Analyzer II sequencing; Ricochet transcription of pachyt

Experiment list: ERX144518 [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available ene piRNA promoters in mammals Organism=Mus musculus || Sex=male || OrganismPart=testis || StrainOrLine=C57B...,9.5,922 Illumina Genome Analyzer II sequencing; Ricochet transcription of pachyt

Experiment list: ERX144532 [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available ene piRNA promoters in mammals Organism=Mus musculus || Sex=male || OrganismPart=testis || StrainOrLine=C57B...,5.0,146 Illumina Genome Analyzer II sequencing; Ricochet transcription of pachyt

President viidi erilennukiga lennukikandjat uudistama / Katrin Rohtla

Index Scriptorium Estoniae

Rohtla, Katrin, 1966-

2007-01-01

President Toomas Hendrik Ilves lendas ameeriklaste organiseeritud lennuga Sitsiiliasse, et sealt sõita erilennuki pardal USA lennukikandjale USS Enterprise. Koos presidendiga käisid lennukikandjat uurimas Riigikogu esimees Ene Ergma ja Riigikogu liige Mati Raidma

Manifestically correct / Harry Liivrand

Index Scriptorium Estoniae

Liivrand, Harry, 1961-

2000-01-01

Euroopa kaasaegse kunsti biennaal Manifesta 3 Ljubljanas deviisi all "Piirijoone sündroom. Kaitsmise energiad". Eestit esindab Ene-Liis Semper videoinstallatsiooniga "FF / Rew". Aleksandr Breneri aktsioonist. Bosnia-Hersegoviina kunstniku Sejla Kamerici tööst jm

Claisen, Cope and Related Rearrangements in the Synthesis of Flavour and Fragrance Compounds

Directory of Open Access Journals (Sweden)

Janusz Nowicki

2000-08-01

Full Text Available A review of the use of the Claisen, Cope and related [3,3]-sigmatropic rearrangements, sequential ("tandem" sigmatropic rearrangements and the "ene" reaction in the syntheses of flavour and fragrance compounds is presented.

Kas hakkas hirm võõrale maale ära kaduda? / Mööna Tilder

Index Scriptorium Estoniae

Tilder, Mööna

2010-01-01

Eike Ülevainu, Jaak Sapase ning Eneli Meresmaa lavastus "Estonia Meets Africa ehk Vaade eemalt", mis kannab tinglikult dokumentaallavastuse nime ja esitatakse nüüdistantsu ja -teatri vormis. Esietendus 9. dets. Tallinna Meistrite Hoovi teatrisaalis

Tantsuline vaade kodusele Eestimaale Aafrikast / Tiiu Laks

Index Scriptorium Estoniae

Laks, Tiiu, 1984-

2009-01-01

9. dets. esietendub Tallinna Meistrite Hoovi teatrisaalis Eike Ülevainu, Jaak Sapase ning Eneli Meresmaa lavastus "Estonia Meets Africa ehk Vaade eemalt", mis kannab tinglikult dokumentaallavastuse nime ja esitatakse nüüdistantsu ja -teatri vormis

Regional tectonic trends on the inner continental shelf off Konkan and central west coast of India

Digital Repository Service at National Institute of Oceanography (India)

Ramana, M.V.

Satellite imagery and offshore magnetic data were analysed to correlate regional tectonic elements on the inner continental shelf off Konkan and the adjacent Deccan plateau. Three statistically important lineament trends N-S, WNW-ESE and ENE...

NIR–FT Raman, FT–IR and surface-enhanced Raman scattering ...

Indian Academy of Sciences (India)

Administrator

Single crystals of (S)-phenylsuccinic acid (SPSA) were grown by the slow evaporation tech- nique and vibrational ... the shift of Raman frequencies, enhancing or weak- ening of .... Harmonic vibrational wave numbers were cal- culated using ...

Research on Leadership, Motivation and Quality of Life in the Air Force Missile and Tanker Units

Science.gov (United States)

1977-06-01

studying directly the results of applying different management principles in leading organizations. Enlight - ened management had demonstrated In... technologies for handling individual differences are fairly simple and straightforward. The demands placed upon analyses involving relationships and

Milleks on vaja (koledat) kirjandust? / Kurt, pseud Moor, pseud.

Index Scriptorium Estoniae

Moor, Kurt, pseud

2004-01-01

Sari "Moodne aeg" kirjanduslike kolmapäevade raames (toimus 27. okt. 2004). Tutvustati Bret Easton Ellise "Ameerika psühhopaati" (Jaanus Adamson), Ian McEwani "Tsementaeda" (Ene-Reet Soovik) ja Martin Amise loomingut (Valle-Sten Maiste)

Kohtunik taandas end Korbi süüasjast

Index Scriptorium Estoniae

2003-01-01

Ida-Viru maakohtu kohtunik Loretta Pikma taandas end objektiivsuse huvides võltsimises ja riisumises süüdistatava Kohtla-Järve keskerakondlasest linnapea Valeri Korbi ja linnasekretär Ene Erro süüasja arutamisest

Eksperimendid animatsioonis ja liikuvad pildid = Experiments in Animation and Moving Pictures / Mari-Liis Rebane

Index Scriptorium Estoniae

Rebane, Mari-Liis, 1988-

2011-01-01

Tallinna XV graafikatriennaal "Armastuse, mitte raha pärast" Kumu Kunstimuuseumis. Triennaalil eksponeeritud animafilmidest, autorid Edmunds Jansons, Stacey Steers, Wojciech Bakowski, Urte Budinaite, Martin Arnold)

Enneolematud ja pärasttulematud indiviidid / Tiiu Leis

Index Scriptorium Estoniae

Leis, Tiiu

1998-01-01

Chaplini kunstikeskuses ja Pärnu mudaravilas avatud autopotreede näitusest 'Ma tunnen end paremini', lähemalt Ene-Liis Semperi videointallatsioonist 'Edasi-tagasi', John Coplansi, Pedro da Cruzi ja Kärt Putki töödest

Süütust näpates : Tanel Veenre fotoseeria teatrikostüümidest Draamateatri laval / Tanel Veenre, Hanna Tiidus, Margit Soosaar...[jt.

Index Scriptorium Estoniae

2007-01-01

Stilist: Hanna Tiidus. Naine: Merle Palmiste. Poiss: Joonas (MJ-Models). Kostüümid etendustest "Rohuvoodi" (Aime Unt), "Rehepapp", "Tõeline inspektor koer" (Ene-Liis Semper), "Liilia" (Lilja Blumenfeld), "Mort" (Kersti Varrak), "Potilaadale" (Reet Aus), "Amadeus" (Krista Tool)

Miks, kuidas ja kellele? / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2009-01-01

Tiit Ojasoo ja Ene-Liis Semperi "Kuidas seletada pilte surnud jänesele" teatris NO99, Priit Võigemasti "Hecuba pärast" Tallinna Linnateatris ja koreograaf-esitaja Mart Kangro "Can't Get No Satisfaction" Kanuti Gildi saalis

Kovjor-samoljot bez opozhavatelnõh zhakov / Vitali Andrejev

Index Scriptorium Estoniae

Andrejev, Vitali

2005-01-01

Kunstinäitus TRINITY Tallinna Vene saatkonna galeriis. Näitusel demonstreeritud Ene-Liis Semperi tööst "ArtVideo", Moskva fotograafi Anton Litvini projektist "Punktuatsioon" ja Moskva kunstniku Bogdan Mamonov maaliseeriast "Ma kanoniseerisin oma sõbrad"

Kohtunikud asusid end Korbi süüasja arutamiselt taandama / Erik Kalda

Index Scriptorium Estoniae

Kalda, Erik, 1969-

2003-01-01

Ilmunud ka: Severnoje Poberezhje 14. märts lk. 1. Ida-Viru maakohtu kohtunik Loretta Pikma taandas end Kohtla-Järve linnapea Valeri Korbi ja linnasekretär Ene Erro kriminaalasja arutamisest. Vt. samas: Korbi-Erro kohtusaaga

Jointing patterns and tectonic evolution of the Maciço Calcário Estremenho, Lusitanian Basin, Portugal

Science.gov (United States)

Carvalho, Jorge M. F.

2018-05-01

The Maciço Calcário Estremenho (MCE) is an uplifted Jurassic limestone massif unit of the Lusitanian Basin, Portugal, where five main joint sets trending NNE-SSW, WSW-ENE, WNW-ESE, NW-SE, and NNW-SSE are recognized. Except for the NNW-SSE set, all the other sets host calcite veins and barren joints, evidencing a multistage development by several deformation episodes, including shear reactivation. Orthogonal patterns defined by the NNE-SSW/WNW-ESE and NNW-SSE/WSW-ENE systems are characteristic of some tectonostratigraphic units of the MCE, but the sets of each one of the systems are genetically independent. They result from specific deformation episodes undergone by the studied area in the course of its Meso-Cenozoic evolution. NNE-SSW calcite veins were the first to form during Middle Jurassic fault-controlled subsidence. A renewal of this set as barren joints took place during the Eocene Pyrenean compressive phase. The WSW-ENE and WNW-ESE sets have a restricted spatial distribution and relate to transient compressive episodes of the Middle - Late Jurassic and Jurassic - Cretaceous transitions, respectively. The NW-SE set, also characteristic of a specific region, formed during the Late Jurassic rifting and is related to local NE-SW tension dependent on block tilting towards a major NW-SE fault. The Miocene Betic compressive phase is responsible for the formation of the NNW-SSE set, which is widespread throughout the MCE.

Zaštita računarskih mreža / Protection of computer networks

Directory of Open Access Journals (Sweden)

Milojko Jevtović

2005-09-01

Full Text Available U radu su obrađene metode napada, oblici ugrožavanja i vrste pretnji kojima su izložene računarske mreže, kao i moguće metode i tehnička rešenja za zaštitu mreža. Analizirani su efekti pretnji kojima mogu biti izložene računarske mreže i informacije koje se preko njih prenose. Opisana su određena tehnička rešenja koja obezbeđuju potreban nivo zaštite računarskih mreža, kao i mere za zaštitu informacija koje se preko njih prenose. Navedeni su standardi koji se odnose na metode i procedure kriptozaštite informacija u računarskim mrežama. U radu je naveden primer zaštite jedne lokalne računarske mreže. / In this paper different methods of attacks, threats and different forms of dangers to the computer networks are described. The possible models and technical solutions for networks protection are also given. The effects of threats directed to the computer networks and their information are analyzed certain technical solutions that provide necessary protection level of the computer networks as well as measures for information protection are also described. The standards for methods and security procedure for the information in computer networks are enlisted. There is also an example of protecting one local data network (in this paper.

Ajatu Ita Ever pühendab end jäägitult teatrile / Rein Veidemann

Index Scriptorium Estoniae

Veidemann, Rein, 1946-

2006-01-01

Näitleja Ita Everi 75. sünnipäeva puhul. Arvamust tema kohta avaldavad ka näitlejad Aleksander Eelmaa, Rasmus Kaljujärv, Tiit Sukk, teatrikunstnikud Ene-Liis Semper ja Aime Unt, teatrinõunik Tõnu Lensment

stakeholders' perceptions of cocoa extension constraints in ghana

African Journals Online (AJOL)

User

The key findings were that all concurred that productivity should be boosted to improve the lot of farmers and ... coa trees infected with the deadly swollen shoot virus disease. .... ence in decision-making processes are strength- ened. District.

Tectonic reactivation in the Indian Ocean: Evidences from seamount morphology and manganese nodule characteristics

Digital Repository Service at National Institute of Oceanography (India)

Mukhopadhyay, R.; Khadge, N.H.

The Central Indian Ocean Basin (CIOB) was subjected to tectonic reactivation in geological past which is unusual for a basin occurring on an apparently single tectonic plate. ENE-WSW trending latitude parallel zone of reactivation across the central...

Алексий II 1929-2008

Index Scriptorium Estoniae

2008-01-01

Aleksius II meenutavad: Kornelius, Tallinna ja kogu Eesti metropoliit ; Karin Jaani ; Marina Kaljurand ; Dmitri Medvedev, Venemaa president ; Helene Kamzol, Aleksius II sugulane ; Ain Seppik ; Vladimir Illjashevitsh ; Edgar Savisaar ; Jevgeni Tomberg ; Ene Ergma ; Toomas Hendrik Ilves, Eesti Vabariigi president

Депутат получит компенсаций более 1000 евро / Ханнели Руди, Аннели Аммас

Index Scriptorium Estoniae

Руди, Ханнели

2011-01-01

Riigikogulaste kuluhüvitis ja eluasemekompensatsioon suurenesid tänavu kevadel, neid tõstetakse veelgi 2012. aastal. Üür, kütte, elektri- ja prügiveokulud. Jaanus Rahumägi, Erki Noole, Ene Ergma kommentaare. Diagramm

Eesti kunst Pariisis

Index Scriptorium Estoniae

2008-01-01

Eesti, läti ja leedu kaasaegse kunsti näitus Pariisis Cite Internationale des Arts galeriis. Eesti osa kuraator on Aili Vahtrapuu. Eksponeeritakse Ene-Liis Semperi, Anu Põdra, Peeter Alliku, Anu Kalmu, Virge Jõekalda jt. kunstnike loomingut

Uus video, uus Euroopa / Kiwa

Index Scriptorium Estoniae

Kiwa, pseud., 1975-

2006-01-01

New Yorgi kunstikeskuses The Kitchen avatud endiste idablokimaade videokunstnike tööde näitusest. Eestlastest eksponeeritud Kiwa, Ene-Liis Semperi, Killu Sukmiti, Mari Laanemetsa, Tiia Johannsoni ja Kai Kaljo tööd. Kuraator Hamza Walker

New lupane triterpenoids from Solidago canadensis that inhibit the lyase activity of DNA polymerase beta.

Science.gov (United States)

Chaturvedula, V S Prakash; Zhou, Bing-Nan; Gao, Zhijie; Thomas, Shannon J; Hecht, Sidney M; Kingston, David G I

2004-12-01

Bioassay-directed fractionation of a methyl ethyl ketone extract of Solidago canadensis L. (Asteraceae), using an assay to detect the lyase activity of DNA polymerase beta, resulted in the isolation of the four new lupane triterpenoids 1-4 and the seven known compounds lupeol, lupeyl acetate, ursolic acid, cycloartenol, cycloartenyl palmitate, alpha-amyrin acetate, and stigmasterol. The structures of the new compounds were established as 3beta-(3R-acetoxyhexadecanoyloxy)-lup-20(29)-ene (1), 3beta-(3-ketohexadecanoyloxy)-lup-20(29)-ene (2), 3beta-(3R-acetoxyhexadecanoyloxy)-29-nor-lupan-20-one (3), and 3beta-(3-hetohexadecanoyloxy)-29-nor-lupan-20-one (4), respectively, on the basis of extensive 1D and 2D NMR spectroscopic interpretation and chemical modification studies. All 11 compounds were inhibitory to the lyase activity of DNA polymerase beta.

Selective distribution of enzymes in a microfluidic reactor

DEFF Research Database (Denmark)

Daugaard, Anders Egede; Pereira Rosinha Grundtvig, Ines; Krühne, Ulrich

Off stoichiometric thiol-ene mixtures are well suited for preparation of microfluidic devices with highly functional surfaces. Here a two stage process employing first thiol-ene chemistry (TEC) to prepare two opposite parts of a microfluidic system with a 30x30 mm reactor and subsequently a thiol......-epoxy bonding was used to prepare a fully sealed microfluidic system. The reactor was surface functionalized in-situ with allyl glycidyl ether in different patterns (half-reactor, full-reactor, checkerboard structures) on the surface to provide a controlled distribution of epoxides. The method additionally...... enables the selective immobilization on either top-side or bottom-side or both sides of the reactor. Thereafter horseradish peroxidase was immobilized on the surface and activity tests illustrated how this distribution of the enzyme on the surface could be used to optimize the activity of the enzyme...

Kohustus kannatada, et näha ja mõista. Ene Mihkelsoni ja Ingeborg Bachmanni kirjanikunägemus. The Writer’s Duty to Suffer in Order to See and Understand: The Literary Vision of Ene Mihkelson and Ingeborg Bachmann

Directory of Open Access Journals (Sweden)

Aija Sakova

2012-04-01

Full Text Available In an interview from 1971 the Austrian poet and author Ingeborg Bachmann (b 1923 said that there are phenomena that science and scientific language cannot explain. According to her these are the phenomena that belong to the realm of writers and literature. In the same year Ene Mihkelson (b 1946, who had not yet published a single book of poetry or a novel because of censorship, pondered on the role of the author within society: “The author digs under the surface and the author’s responsibility to society lies in his/her persistence, in his/her duty to suffer, to endure stress, which the people in the midst of their busy, daily lives are unable to fully grasp.” Responsibility to society and the duty to suffer and explore the deepest layers below the surface are common to both Mihkelson and Bachmann. Both writers were born and grew up in the shadow of war, violence and totalitarianism. Mihkelson was brought up in a guerrilla family in Soviet Estonia; Bachmann spent her childhood years growing up in the Nationalist-Socialist Austria and in her youth she witnessed the Second World War and its catastrophic consequences. So both of them understand that as writers they cannot overlook the events that they had, either directly or indirectly, witnessed. In an interview from 2009 Mihkelson said that the fact that she remained alive while many did not, that she was not deported to Siberia although it could have happened, has obligated her to write and reflect on what had happened. No consensus has been reached in Europe to condemn Communism as a crime against humanity, but for Estonians Communism and the 50 years of Soviet regime signify a lengthy experience of a totalitarian regime and, in spite of a possible opposition from German-speaking cultures, Communism very often equals Nazism in Estonia. According to Mihkelson, in order to understand and reflect this experience it is not sufficient to rely only on the archives, biographies and books of

Application of microwave irradiation to organic liquid phase reactions

International Nuclear Information System (INIS)

Huang Kun; Liu Hua; Ji Xuelin

1994-01-01

Microwave irradiation has been used in organic liquid phase reactions to significantly reduce the reaction time and improve the yield. The proposed mechanism, the development of techniques and reactions, such as Diels-Alder, ene, rearrangement reactions etc., are discussed

OLD AND SAD — DEPRESSION IN LATER LIFE

African Journals Online (AJOL)

Enrique

of elderly citizens as the AIDS epidemic plateaus. Increased life expectancy will be due to improved health and social conditions. Hence clinicians .... ive social network. Studies have ... spread, and one outcome is the damp- ening down of an ...

Ettevaatust, ohtlik elektrishokirelv! / Gunnar Press

Index Scriptorium Estoniae

Press, Gunnar, 1957-

2008-01-01

Elektrishokirelva kasutuselevõtu arutelust seoses politseiseaduse ja sellega seonduvate seaduste muutmise eelnõuga. USA ajakirjanik Christopher Bollyn elektrishokirelvast. Lisatud: kas pooldate elektrishokirelva kasutuselevõttu? : vastavad justiitsminister Rein Lang, siseminister Jüri Pihl ja Riigikogu esimees Ene Ergma ; õiguskomisjoni piirangud

chama et al

African Journals Online (AJOL)

PUBLICATIONS1

electrical equipment (EEE) globally has in- creased its obsolescence ... which is about 5% of municipal waste (OECD, ... a result of extensive pollution, the river is virtu- ally dead. ... ene bags and transported in an ice cooler. A ... Quality control.

12. VI avati Salzburgi maineka Kunstiühingu (Salzburger Kunstverein) peasaalis...

Index Scriptorium Estoniae

2003-01-01

Ene-Liis Semperi videonäitus. Eksponeeritakse 1998. a. valminud töid, mis käsitlevad elu ja surma piirsituatsiooni. Austria päevalehe Die Presse kultuurilisa nimetab E.-L. Semperit viimase Veneetsia biennaali Eesti shooting-star'iks

Steroids from marine sponges Suberites vestigium and Chrotella australiensis

Digital Repository Service at National Institute of Oceanography (India)

Mishra, P.D; Wahidullah, S.; De; Kamat, S.Y.

The sponges Suberites vestigium and Chrotella australiensis have been examined for steriods. Both the sponges contain C sub(27-29) mono and diunsaturated sterols, in addition sponge C. australiensis contains cholest-4-ene-3-one and 24-ethyl cholest...

Eesti foto Berliinis

Index Scriptorium Estoniae

2003-01-01

Berliinis Giedre Bartelti galeriis kaheksa eesti kunstniku fotonäitus "(Un)Dressed Body in the Baltic Photo Art vol. 2 : Estonia" - Ene-Liis Semper, Peeter Laurits, Mark Raidpere, Liina Siib, Ly Lestberg, Mare Tralla, Margot Kask ja Tanel Veenre

Jah, proua president / Aune Past

Index Scriptorium Estoniae

Past, Aune, 1954-

2006-01-01

Autor analüüsib, kes Eesti lugupeetud naistest võiks asuda presidenditoolile, pakkudes kandidaatideks Marju Lauristini, Siiri Oviiri, Ingrid Rüütli, Ene Ergma; Mari-Ann Kelami, Vilja Savisaare ja Maimu Bergi. Kommenteerivad Valve Raudnask ja Barbi Pilvre

Muinasjutt, mis ootas pool sajandit / Sirje Maasikamäe

Index Scriptorium Estoniae

Maasikamäe, Sirje, 1963-

1995-01-01

Lavastaja Grigori Kromanov. Mälestused, artiklid, kirjad, päevikud / koost. Irena Veisaite-Kromanova; Panso, Voldemar. Töö ja talent näitleja loomingus; Sinine vöö : Valik muinasjutte / Kkoost., tlk. ja lastele jutustanud Ene ja Paul Ambur

Rein Raua kuraatoridebüüt

Index Scriptorium Estoniae

2001-01-01

Hausi galeriis Rein Raua kureeritud rahvusvaheline kunstinäitus "KevadSuviSügisTalv. Murdumispunkt". Esinevad Eve Kask, Peeter Laurits, Dainius Lickevicius, Rehka Menon, Mall Nukke, Herkki Merila, Jorma Puranen, Rosita Raud, Ene-Liis Semper, Liina Siib, S. ja P. Stanikas

Mõis Padaoru nõlvadel / Jana Rand

Index Scriptorium Estoniae

Rand, Jana, 1963-

2013-01-01

Pada mõisa kõrvalhoonetest on osa renoveeritud: viljaait, viinavabrik, meierei. Suursugune härrastemaja (arhitekt Jean Baptiste Vallin de la Mothe) seisab aga juba pea sajand varemeis. Vestlusest kõrvalhoonete praeguste omanike Urve Eriksoni, Ene Ehrenpreisi ja Michel Poulain'iga

Phytochemical analysis of Cyrtanthus obliquus bulbs from the ...

African Journals Online (AJOL)

Proff.Adewunmi

dihydroxy-lanosta-8-ene was also isolated from the bulbs. The ... Fresh bulbs from C. obliquus were purchased at the Berea market in Durban and identified by a curator from the School of Biological and. Conservation Sciences, UKZN, Westville ...

Protein tetrazinylation via diazonium coupling for covalent and catalyst-free bioconjugation.

Science.gov (United States)

Zhang, Jie; Men, Yuwen; Lv, Shanshan; Yi, Long; Chen, Jian-Feng

2015-12-21

An efficient and bench-stable reagent was synthesized for direct and covalent introduction of tetrazines onto target protein or virus surfaces, which can be further modified based on tetrazine-ene ligation to achieve fluorescence labelling or PEGylation under mild conditions.

Kõik on kunst, kunst on kõikjal / Tiiu Leis

Index Scriptorium Estoniae

Leis, Tiiu

1998-01-01

25. juulil toimus Pärnus raehoovis kehamaalimise üritus, mille kuraatoriks Ene-Liis Semper, kunstnikud Marko Laimre, Kiwa, Jasper Zoova, Tarrvi Laamann ning mis toimus Barclay sigarettide reklaamikampaania 'Art is Everywhwere' (eestipoolne korraldaja Per Li ehk Pear Väli) raames.

Ingmar Muusikuse foto Flash Artis

Index Scriptorium Estoniae

1999-01-01

Flash Arti 1999. a. oktoobrinumbris virtuaalse näituse rubriigis Ando Keskküla artikkel radikaalsemast eesti kunstist ja kunstielust postsotsialistlikul ajastul. Illustratsiooniks Liina Siibi fotokompositsioonid, Ingmar Muusikuse foto Raoul Kurvitza, Ene-Liis Semperi ja Kiwa Eesti Panga performance'ist

Kui suur on maailmakirjandus? / Cornelius Hasselblatt

Index Scriptorium Estoniae

Hasselblatt, Cornelius, 1960-

2015-01-01

Arvustus: Aija Sakova-Merivee. Ausgraben und Erinnern. Denkbilder des Erinnerns und der moralischen Zeugenschaft im Werk von Ene Mihkelson und Christa Wolf. Tartu : University of Tartu Press, c2014. (Dissertationes litterarum et contemplationis comparativae Universitatis Tartuensis, 1406-913X ; 13)

A new synthesis of Entacapone and report on related studies

Indian Academy of Sciences (India)

demethylation since the methoxyl oxygen atom is not conjugating with the .... The energy minimization was also carried out for ... the energy minimized structures of 1 and 2, as shown ... ened singlet at 3.52 ppm (instead of the usual quar- tet).

Igor Gräzin predlagajet suditsja s glavoi PASE

Index Scriptorium Estoniae

2007-01-01

Riigikogu liige Igor Gräzin arvab, et Eesti võiks kaaluda võimalust anda kohtusse ENPA president Rene van der Linden, kes on laimanud Eesti riiki. Riigikogu esimehe Ene Ergma kirjast ENPA presidendile Rene van Lindenile ja tema vastusest

Jõgeval kuulutati jõulurahu kogu Eestile / Ardi Kivimets

Index Scriptorium Estoniae

Kivimets, Ardi, 1947-

2008-01-01

7. detsembril kuulutas peapiiskop Andres Põder Jõgeval välja ülemaalise jõulurahu ning süütas koos riigikogu esimehe Ene Ergma ja Jõgeva linnapea Viktor Svjatõ̧eviga linna jõulukuusel teise advendiküünla

Reiljan, Savisaar show who's in charge / Joel Alas

Index Scriptorium Estoniae

Alas, Joel

2006-01-01

Eestimaa Rahvaliidu esimees Villu Reiljan ja Eesti Keskerakonna esimees Edgar Savisaar otsustavad uue presidendi üle. Villu Reiljan toetab Arnold Rüütlit. Edgar Savisaare, Ene Ergma, Toomas Hendrik Ilvese ja Riigikogu liikme Ain Seppiku väljaütlemised

Journal of Earth System Science | Indian Academy of Sciences

Indian Academy of Sciences (India)

sectional geometry normal to the regional strike (ENE –WSW),with the thickest part occurring to the south,and is divisible into four groups:Semri,Kaimur,Rewa and Bhander,from bottom to top.The boundary between the Semri and Kaimur ...

Analysis of efflorescence on surface of beeswax seals

Czech Academy of Sciences Publication Activity Database

Bartl, B.; Trejbal, J.; Ďurovič, M.; Vašíčková, Soňa; Valterová, Irena

2012-01-01

Roč. 13, č. 3 (2012), s. 275-284 ISSN 1296-2074 Institutional research plan: CEZ:AV0Z40550506 Keywords : beeswax bloom * (Z)-tritriacont-10-ene * efflorescence * unsaturated hydrocarbons Subject RIV: CC - Organic Chemistry Impact factor: 1.176, year: 2012

The Combat-System/Ship-System Interface,

Science.gov (United States)

1982-02-01

sequence initiated by removal of the load shed signal. Re-eneAgize capabitiLty. Provide remotely controlled reclosable power control devices to...signal from the electrical plant control equipment. The power controllers would replace existing circuit breakers and incorporate reclose capability

Woody Alleni komöödia Rakveres / Peeter Raudsepp

Index Scriptorium Estoniae

Raudsepp, Peeter, 1974-

1999-01-01

Rakvere Teatris esietendub 15. okt "Suveöö seksikomöödia", Woody Alleni filmistsenaariumi on näidendiks kirjutanud Jürgen Fischer, lavastab külalisena Rednar Annus, kunstnikud on Ene -Liis Semper ja Raoul Kurvitz, muusikaline kujundaja Tamur Tohver.

Videokunsti parimad stiilinäited Kumus

Index Scriptorium Estoniae

2010-01-01

Kumu Kunstimuuseumis avatakse 28. oktoobril 2010 rahvusvaheline videokunsti näitus "Kõik saab korda". Osalevad Marina Abramović (Serbia/USA), Eija-Liisa Ahtila (Soome), Kai Kaljo, Mike Marshall (Inglismaa), Ene-Liis Semper, Santeri Tuori (Soome), Guido van der Werve (Holland)

Well-defined triblock copolymers of polyethylene with polycaprolactone or polystyrene using a novel difunctional polyhomologation initiator

KAUST Repository

Hadjichristidis, Nikolaos; Alshumrani , Reem

2017-01-01

α,ω-Dihydroxy polyethylene was synthesized by polyhomologation of dimethylsulfoxonium methylide with 9-thexyl-9-BBN (9-BNN: 9-Borabicyclo[3.3.1]nonane), a novel difunctional initiator produced from 9-BBN and 2,3-dimethylbut-2-ene, with two active