WorldWideScience

Sample records for kommenteerinud ene rebane

  1. Kuidas suhtute erakooli? / Andrus Kuusmann, Rein Rebane, Tiiu Kuurme ... [jt.

    2012-01-01

    Küsimusele vastavad Tartu erakooli nõukogu esimees Andrus Kuusmann, Rocca al Mare Kooli AS-i juhataja Rein Rebane, TLÜ õppejõud Tiiu Kuurme, Viljandi Waldorfkooli õpetaja Sulev Ojap ja TLÜ õppejõud Tõnu Ploompuu

  2. Pilk uuele "Põhjamaade romaani" sarjale / Hilve Rebane

    Rebane, Hilve, 1938-2012

    1999-01-01

    Bengtson, Frans G. Orm Punane / tlk. Anu Saluäär. Tallinn : Eesti Raamat, 1997 ; Wassmo, Herbjırg. Dina raamat / tlk. Elvi Lumet. Tallinn : Eesti Raamat, 1997 ; Tunström, Göran. Varas / tlk. Ene Mäe. Tallinn : Eesti Raamat, 1999

  3. Nava tiigi ääres seiklevad Hunt ja Rebane / Liisi Seil ; kommenteerinud Pille Põllumäe

    Seil, Liisi, 1971-

    2009-01-01

    17.-19. juulini Lilli külas Nava talus toimuvast 4. Nava lava festivalist. 19. 07 mängib Karksi valla kultuurikeskuse noorteteater "O" lasteetendust "Hundi ja Rebase lend lõunanabale", mille on Nava talu peremehe Jaak Kõdari raamatu "Kriimureinulised lood. 3, Argonaudid" põhjal kirjutanud ja lavastanud Silvia Soro. Kostüümid tegi Thea Ilusmets. 17., 18. ja 19. 07 mängitakse Jaak Kõdari mulgikeelset külanäitemängu "Kõik läheb mööda, kõik tuleb jälle. 1912-1918", lavastaja Silvia Soro

  4. Kuidas kommenteerite hoolekogu rolli enda koolis? / Mihkel Rebane, Margus Leek, Hannes Astok ... [jt.

    2011-01-01

    Küsimusele vastavad Kiili gümnaasiumi direktor Mihkel Rebane, Mart Reiniku gümnaasiumi hoolekogu vilistlaste esindaja Margus Leek, riigikogulane, HTG hoolekogu liige Hannes Astok, Puurmani gümnaasium õpilasesinduse president Kertu Vahtra ja Saku gümnaasiumi hoolekogu esimees Aare Järvelaid

  5. Microbial synthesis of alka(enes

    Weihua eWang

    2013-10-01

    Full Text Available Alka(enes are the predominant constituents of gasoline, diesel, and jet fuels. They can be produced naturally by a wide range of microorganisms. Bio- alka(enes can be used as drop-in biofuels. To date, five microbial pathways that convert free fatty acids or fatty acid derivatives into alka(enes have been identified or reconstituted. The discoveries open a door to achieve microbial production of alka(enes with high efficiency. The modules derived from these alka(ene biosynthetic pathways can be assembled as biological parts and synthetic biology strategies can be employed to optimize the metabolic pathways and improve alka(ene production.

  6. Ene Sepp esitles esikteost "Medaljon" / Heli Talinurm

    Talinurm, Heli

    2009-01-01

    Ene Sepp esitles 19. veebruaril Rapla Keskraamatukogus oma raamatut, mis pälvis kolmanda koha Eesti Lastekirjanduse Teabekeskuse ja kirjastuse Tänapäev 2008. aasta noorsooromaani võistlusel. Ly Ehini mõtteid, mida Ene Sepa raamat temas tekitas

  7. Söötmisega disainitud piim tagab tervisliku toidukraami / Ene Tammsaar ; intervjueerinud Ain Alvela ; kommenteerinud Üllas Jaaska

    Tammsaar, Ene, 1952-

    2014-01-01

    Et farmidest tööstusse minevast toorpiimast saaks toota maitsvaid ja tervislikke tooteid, peab toorpiim olema kõrgeima võimaliku kvaliteediga. Selle tagamiseks on piimatööstused koostöös teadlastega ette võtnud piima koostise disainimise

  8. ENES the European Network for Earth System modelling and its infrastructure projects IS-ENES

    Guglielmo, Francesca; Joussaume, Sylvie; Parinet, Marie

    2016-04-01

    The scientific community working on climate modelling is organized within the European Network for Earth System modelling (ENES). In the past decade, several European university departments, research centres, meteorological services, computer centres, and industrial partners engaged in the creation of ENES with the purpose of working together and cooperating towards the further development of the network, by signing a Memorandum of Understanding. As of 2015, the consortium counts 47 partners. The climate modelling community, and thus ENES, faces challenges which are both science-driven, i.e. analysing of the full complexity of the Earth System to improve our understanding and prediction of climate changes, and have multi-faceted societal implications, as a better representation of climate change on regional scales leads to improved understanding and prediction of impacts and to the development and provision of climate services. ENES, promoting and endorsing projects and initiatives, helps in developing and evaluating of state-of-the-art climate and Earth system models, facilitates model inter-comparison studies, encourages exchanges of software and model results, and fosters the use of high performance computing facilities dedicated to high-resolution multi-model experiments. ENES brings together public and private partners, integrates countries underrepresented in climate modelling studies, and reaches out to different user communities, thus enhancing European expertise and competitiveness. In this need of sophisticated models, world-class, high-performance computers, and state-of-the-art software solutions to make efficient use of models, data and hardware, a key role is played by the constitution and maintenance of a solid infrastructure, developing and providing services to the different user communities. ENES has investigated the infrastructural needs and has received funding from the EU FP7 program for the IS-ENES (InfraStructure for ENES) phase I and II

  9. Kandidaadid : Ene Ergma versus Toomas Hendrik Ilves

    2006-01-01

    Artiklis vastatakse küsimustele, kes oleksid Kadriorus Ene Ergma ja Toomas Hendrik Ilvese nõunikud, millist sõnumit kannaks nende esimene iseseisvuspäeva kõne, kuidas nad tähistaksid oma võitu presidendivalimistel, kellele nad annaksid Maarjamaa Risti, kuhu nad teeksid oma esimese välisvisiidi

  10. Pronkssõduri teisaldamise ainsaks eelduseks on referendum / Kalev Rebane, Roman Zharov, Aleksandr Korobov...[jt.] ; interv. Peeter Ernits, Jüri Aarma, Annika Poldre

    2006-01-01

    Oma seisukohtadest Tallinnas Tõnismäel asuva Teise maailmasõja mälestusmärgi suhtes räägivad isamaaliitlane Kalev Rebane ja vene noorteühenduse Notshnoi Dozor juhid Roman Zharov, Aleksandr Korobov, Oleg Filippov ja Igor Rogo

  11. Aisopose lood / Aisopos ; tõlkinud ja kommenteerinud Kaarina Rein (96, 27, 119, 126, 143, 303) ja Janika Päll (72)

    Aisopos, 6.saj. e.Kr.

    2006-01-01

    Sissejuhatus lk. 395, kommentaarid lk. 587-588. - Sisu: 96: Reetor Demades ; 27: Kalur, kes vett peksis ; 72: Härjakarjus ja Herakles : [luuletus] ; 119: Zeus ja rebane ; 126: Kohtumõistja Zeus ; 143: Pilliroog ja õlipuu ; 303: Kaks nahkpauna

  12. Ene Käpp ali optimizem

    Dušana Findeisen

    1998-12-01

    Full Text Available Na »Konferenci o vlogi in organizaciji izobraževanja odraslih v času prehoda«, ki je bila novembra lani v Tallinnu, glavnem mestu Estonije, smo srečevali nekaj razsvetljenih obrazov organizatorjev. Med njimi je bila Ene Kapp, kratko pristriženih las, živahnega videza in prodornega glasu. Ene Kapp je neprestano bedela nad nami. Tisti, ki so povezani z estonskim izobraževanjem odraslih, jo poznajo že dolgo. Srečujejo se z njo na ANDRAS-u, estonskem združenju za izobraževanje odraslih.

  13. IS-ENES project management - lessons learnt

    Parinet, Marie; Guglielmo, Francesca; Joussaume, Sylvie

    2017-04-01

    IS-ENES is the distributed e-infrastructure of models, model data and metadata of the European Network for Earth System Modelling (ENES). It has benefitted from two EC FP7 grants and aims towards further European and national funding to achieve sustainability. We highlight here several challenges related to project management that have risen in the course of these two project-phases spanning 8 years. Some challenges are related to the heterogeneity of the activities within IS-ENES, with different groups working on very diverse activities, not necessarily strictly interdependent. An immediate consequence is the need of implementing and setting up in early phases of the project efficient collection and circulation of information to preserve and reinforce the systemic view of the infrastructure as a whole and the pursuit of common goals, including coordinated provision of services. Toward and beyond such common goals, managing IS-ENES, covering both scientific and more strictly management-related aspects, implies a double-paced approach: besides setting up efficient project workflow, there is the need of setting up longer term objectives. This implies, within the project lifetime, to elaborate and implement a coherent organizational (consistent with scientific goals, funding schemes, research and technology landscape) strategy to pursue these goals beyond the project itself. Furthermore, a series of more generic project management challenges will also be listed and can be gathered around 3 main objectives: ease the internal processes in order to optimize the work, anticipate delays and budget issues, and motivate the project teams by ensuring an efficient internal and external communication.

  14. Hydroxylative activity of Aspergillus niger towards androst-4-ene and androst-5-ene steroids.

    Świzdor, Alina; Panek, Anna; Milecka-Tronina, Natalia

    2017-10-01

    Aspergillus niger, one of fungal species most frequently used for experimental and industrial-scale biotransformations of various organic compounds, is generally known to transform steroids at 16β position. In this work, application of the strain A. niger KCH910 to bioconversion of dehydroepiandrosterone (DHEA), androstenediol and testosterone is described, with emphasis on the metabolic steps leading to the products. Evidence from this study indicated that incubated 5-ene steroids underwent bioconversion within two metabolic pathways: oxidation by the action of 3β-HSD (3β-hydroxysteroid dehydrogenase) to 4-ene steroids, and minor allylic hydroxylation to epimeric 7-alcohols. Further transformation of the 3-oxo-4-ene metabolites resulted in non-selective 16-hydroxylation. It is the first report on an A. niger strain able to introduce not only 16β- but also 16α-hydroxyl function into steroids. Copyright © 2017. Published by Elsevier Inc.

  15. Hybrid Organic/Inorganic Thiol-ene-Based Photopolymerized Networks

    Schreck, Kathleen M.; Leung, Diana; Bowman, Christopher N.

    2011-01-01

    The thiol-ene reaction serves as a more oxygen tolerant alternative to traditional (meth)acrylate chemistry for forming photopolymerized networks with numerous desirable attributes including energy absorption, optical clarity, and reduced shrinkage stress. However, when utilizing commercially available monomers, many thiol-ene networks also exhibit decreases in properties such as glass transition temperature (Tg) and crosslink density. In this study, hybrid organic/inorganic thiol-ene resins ...

  16. Sa uurisid ekspressionismi 1960ndatel ja 70ndatel... / Ene Lamp

    Lamp, Ene

    2005-01-01

    2004. a. ilmunud raamatu "Ekspressionism" eest Eesti Kultuurkapitali suure kunstipreemia (100000 kr.) saanud Ene Lamp ekspressionismi tähenduse muutumiset, ekspressionismi rollist eesti kunstis, oma tulevikuplaanidest

  17. Synthesis of some 16,17-secoandrost-5-ene derivatives

    Gaković Andrea R.

    2010-01-01

    Full Text Available Starting from 3β-acetoxy-17-oxo-16,17-secoandrost-5-ene-16-nitrile (1, 3β-acetoxy-16,17-secoandrost-5-ene-16-nitrile (4 was synthesized by a three-stage procedure. First, the formyl group of compound 1 was reduced, to yield the alcohol 2. Compound 2 was further transformed to the mesyloxy derivative 3, whose reduction with NaBH3CN gave compound 4. Apart from compound 4 as the main reaction product, two additional products were obtained, for which the GC/MS analysis suggested that they are 8(14 and 14 derivatives of compound 4. Compound 4 was transformed into 3β-hydroxy-16,17-sesoandrost-5-ene-16-nitrile (7, the Oppenauer oxidation of which afforded 3-oxo-16,17-secoandrost-4-ene-16-nitrile (8.

  18. An academic with ambition / Ene Ergma ; interv. Kadri Kukk

    Ergma, Ene, 1944-

    2006-01-01

    Intervjuus Riigikogu asespiikriga käsitletakse kõrghariduse korraldust, professorite rohkust kõrgkoolides, võimalikku kandideerimist Tartu ülikooli rektori kohale, omandatud poliitilisi kogemusi ning ajude äravoolu Eestist. Ene Ergma CV

  19. Tandem Wittig-ene reaction approach to kainic acid

    Majik, M.S.; Parameswaran, P.S.; Tilve, S.G.

    The first example of a tandem Wittig-intramolecular ene reaction approach and its application toward the synthesis of kainic acid is reported. The synthetic pathway involves conversion of prenyl bromide into phosphorane 3, followed by one-pot Wittig...

  20. 5-Ene-4-thiazolidinones - An efficient tool in medicinal chemistry.

    Kaminskyy, Danylo; Kryshchyshyn, Anna; Lesyk, Roman

    2017-11-10

    The presented review is an attempt to summarize a huge volume of data on 5-ene-4-thiazolidinones being a widely studied class of small molecules used in modern organic and medicinal chemistry. The manuscript covers approaches to the synthesis of 5-ene-4-thiazolidinone derivatives: modification of the C5 position of the basic core; synthesis of the target compounds in the one-pot or multistage reactions or transformation of other related heterocycles. The most prominent pharmacological profiles of 5-ene derivatives of different 4-thiazolidinone subtypes belonging to hit-, lead-compounds, drug-candidates and drugs as well as the most studied targets have been discussed. Currently target compounds (especially 5-en-rhodanines) are assigned as frequent hitters or pan-assay interference compounds (PAINS) within high-throughput screening campaigns. Nevertheless, the crucial impact of the presence/nature of C5 substituent (namely 5-ene) on the pharmacological effects of 5-ene-4-thiazolidinones was confirmed by the numerous listed findings from the original articles. The main directions for active 5-ene-4-thiazolidinones optimization have been shown: i) complication of the fragment in the C5 position; ii) introduction of the substituents in the N3 position (especially fragments with carboxylic group or its derivatives); iii) annealing in complex heterocyclic systems; iv) combination with other pharmacologically attractive fragments within hybrid pharmacophore approach. Moreover, the utilization of 5-ene-4-thiazolidinones in the synthesis of complex compounds with potent pharmacological application is described. The chemical transformations cover mainly the reactions which involve the exocyclic double bond in C5 position of the main core and correspond to the abovementioned direction of the 5-ene-4-thiazolidinone modification. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  1. Fabrication and bonding of thiol-ene-based microfluidic devices

    Sikanen, Tiina M; Lafleur, Josiane P.; Moilanen, Maria-Elisa

    2013-01-01

    In this work, the bonding strength of microchips fabricated by thiol-ene free-radical polymerization was characterized in detail by varying the monomeric thiol/allyl composition from the stoichiometric ratio (1:1) up to 100% excess of thiol (2:1) or allyl (1:2) functional groups. Four different...... properties for each application. Here, a capillary electrophoresis separation is performed to demonstrate the attractive properties of stoichiometric thiol-ene microchips....

  2. Highly tailorable thiol-ene based emulsion-templated monoliths

    Lafleur, J. P.; Kutter, J. P.

    2014-01-01

    The attractive surface properties of thiol-ene polymers combined with their ease of processing make them ideal substrates in many bioanalytical applications. We report the synthesis of highly tailorable emulsion-templated porous polymers and beads in microfluidic devices based on off-stoichiometr......The attractive surface properties of thiol-ene polymers combined with their ease of processing make them ideal substrates in many bioanalytical applications. We report the synthesis of highly tailorable emulsion-templated porous polymers and beads in microfluidic devices based on off......-stoichiometry thiolene chemistry. The method allows monolith synthesis and anchoring inside thiol-ene microchannels in a single step. Variations in the monomer stoichiometric ratios and/or amount of porogen used allow for the creation of extremely varied polymer morphologies, from foam-like materials to dense networks...

  3. Thiol-ene/methacrylate systems for mechanical damping

    McNair, Olivia; Senyurt, Askim; Wei, Huanyu; Gould, Trent; Piland, Scott; Hoyle, Charles; Savin, Daniel

    2010-03-01

    Ternary thiol-ene-methacrylate (TEMA) networks as materials for mechanical energy damping are unique to the sports world. Using a photoinitiation process, TEMA systems are formed via an initial thiol-ene step-growth mechanism along with traditional radical polymerization of acrylate and ene monomers. Final networks have two-part morphologies: acrylate homopolymer sectors imbedded in a multi-component mesh. Several (TEMA) systems have been synthesized and analyzed via thermal and mechanical probing. Initial studies on these ternary systems have shown excellent properties compared to traditional ethylene vinyl alcohol (EVA) copolymers. For example, PEMA networks exhibit glass transition temperatures 33 K higher than EVA, resulting in improved damping at room temperature. This research will help develop relationships between tan delta, glass transition and their effects on mechanical energy damping for ternary (TEMA) systems.

  4. Surface functionalized thiol-ene waveguides for fluorescence biosensing in microfluidic devices

    Feidenhans'l, Nikolaj Agentoft; Lafleur, Josiane P.; Jensen, Thomas Glasdam

    2013-01-01

    -ene waveguides were fabricated from 40% excess thiol thiol-ene to ensure the presence of thiol functional groups at the surface of the waveguide. Biotin alkyne was photografted at specific locations using a photomask, directly at the interface between the microfluidic channel and the thiol-ene waveguide prior...

  5. Proof of a conjecture of Colliot-Th\\'el\\`ene

    Denef, Jan

    2011-01-01

    We prove a conjecture of Colliot-Th\\'el\\`ene that implies the Ax-Kochen Theorem on p-adic forms. We obtain it as an easy consequence of a diophantine excision theorem whose proof forms the body of the present paper.

  6. preparation of bicyclic lactones using lewis acids catalyzed ene

    Administrator

    The synthesis of the cis-fused bicyclic lactones relies extensively on the Lewis acid ... having an allylic hydrogen (an"ene") and a compound containing an electron .... observed that the lithium enolate obtained from 3-methyl-2(5H)- furanone ...

  7. Ene ja Tõnis Kask pole valikuga rahul / Tiit Tuumalu

    Tuumalu, Tiit, 1971-

    2003-01-01

    Eesti Filmiajakirjanike Ühing andis auhinna Aasta film 2002 mängufilmile "Agent Sinikael" : režissöör Marko Raat. Viimane sai preemiaks 12 000 krooni. Auhinna rahastajad omanimelise fondi kaudu Eesti Rahvuskultuuri Fondi juures Ene ja Tõnis Kask peavad "Nimed marmortahvlil" väljajätmist isegi nominentide hulgast shokeerivaks

  8. Hybrid Organic/Inorganic Thiol-ene-Based Photopolymerized Networks.

    Schreck, Kathleen M; Leung, Diana; Bowman, Christopher N

    2011-09-15

    The thiol-ene reaction serves as a more oxygen tolerant alternative to traditional (meth)acrylate chemistry for forming photopolymerized networks with numerous desirable attributes including energy absorption, optical clarity, and reduced shrinkage stress. However, when utilizing commercially available monomers, many thiol-ene networks also exhibit decreases in properties such as glass transition temperature (T(g)) and crosslink density. In this study, hybrid organic/inorganic thiol-ene resins incorporating silsesquioxane (SSQ) species into the photopolymerized networks were investigated as a route to improve these properties. Thiol- and ene-functionalized SSQs (SH-SSQ and allyl-SSQ, respectively) were synthesized via alkoxysilane hydrolysis/condensation chemistry, using a photopolymerizable monomer [either pentaerythriol tetrakis(3-mercaptopropionate) (PETMP) or 1,3,5-triallyl-1,3,5-triazine-2,4,6(1H,3H,5H)-trione (TATATO)] as the reaction solvent. The resulting SSQ-containing solutions (SSQ-PETMP and SSQ-TATATO) were characterized, and their incorporation into photopolymerized networks was evaluated.

  9. Fabrication and bonding of thiol-ene-based microfluidic devices

    Sikanen, Tiina M; Moilanen, Maria-Elisa; Lafleur, Josiane P; Zhuang, Guisheng; Jensen, Thomas G; Kutter, Jörg P

    2013-01-01

    In this work, the bonding strength of microchips fabricated by thiol-ene free-radical polymerization was characterized in detail by varying the monomeric thiol/allyl composition from the stoichiometric ratio (1:1) up to 100% excess of thiol (2:1) or allyl (1:2) functional groups. Four different thiol-ene to thiol-ene bonding combinations were tested by bonding: (i) two stoichiometric layers, (ii) two layers bearing complementary excess of thiols and allyls, (iii) two layers both bearing excess of thiols, or (iv) two layers both bearing excess of allyls. The results showed that the stiffness of the cross-linked polymer plays the most crucial role regarding the bonding strength. The most rigid polymer layers were obtained by using the stoichiometric composition or an excess of allyls, and thus, the bonding combinations (i) and (iv) withstood the highest pressures (up to the cut-off value of 6 bar). On the other hand, excess of thiol monomers yielded more elastic polymer layers and thus decreased the pressure tolerance for bonding combinations (ii) and (iii). By using monomers with more thiol groups (e.g. tetrathiol versus trithiol), a higher cross-linking ratio, and thus, greater stiffness was obtained. Surface characterization by infrared spectroscopy confirmed that the changes in the monomeric thiol/allyl composition were also reflected in the surface chemistry. The flexibility of being able to bond different types of thiol-enes together allows for tuning of the surface chemistry to yield the desired properties for each application. Here, a capillary electrophoresis separation is performed to demonstrate the attractive properties of stoichiometric thiol-ene microchips. (technical note)

  10. 5 küsimust Ene Läkile / Ene Läkk ; interv. Ell-Maaja Randküla

    Läkk, Ene, 1957-

    2006-01-01

    Ene Läkist, kes on alates 2005. aastast interjööri-, disaini- ja arhitektuuriajakirja "Ruum" peatoimetaja. Ene Läkk, Eesti Sisearhitektide Liidu 2005. a. aastapreemia nominent ajakirjandusliku tegevuse eest, ajakirjast "Ruum". Ill.: 6 värv. vaadet, foto ajakirjanikust

  11. Ene-Liiz Semper. Anton Litvin. Bogdan Mamonov

    2005-01-01

    Veebruaris Madridis toimunud Euroopa kunstilaada ARCO jaoks Vene saatkonna galerii poolt koostatud kunstinäitus TRINITY toimub nüüd Tallinnas Vene saatkonna galeriis. Kuraatorid Masha ja Andrei Melnikovid. Osalevad Ene-Liis Semper videoga ArtVideo, vene kunstnik Bogdan Mamonov maaliseeriaga "Ma kanoniseerisin oma sõpru" ja vene kunstnik Anton Litvin fotoprojektiga "Punktuatsioon". Madridis näitas Semper videot "Nimetu"

  12. Multi-chamber and multi-layer thiol-ene microchip for cell culture

    Tan, H. Y.; Hemmingsen, Mette; Lafleur, Josiane P.

    2014-01-01

    We present a multi-layer and multi-chamber microfluidic chip fabricated using two different thiol-ene mixtures. Sandwiched between the thiol-ene chip layers is a commercially available membrane whose morphology has been altered with coatings of thiol-ene mixtures. Experiments have been conducted ...... with the microchip and shown that the fabricated microchip is suitable for long term cell culture....

  13. ENE-Mates - A public information program for women

    Nagashima, Kyoko

    1995-01-01

    Japan depends on import for more than 80 percent of its total energy supply. Nuclear energy is one of the most promising alternatives to oil. It plays a significant role for energy supply in terms of reliability, economic viability and reduction of CO 2 emissions. In order to secure needed capacity, the Government concentrates its efforts on acquiring public acceptance of nuclear power as well as ensuring the safety of plants and improving plant capability and reliability. An opinion poll, done by the Japanese Government in Sep. of 1990, showed that 73.3 percent of man and 57.4 percent of women think that nuclear power is necessary to secure energy supply. Nuclear Power Engineering Corporation (NUPEC) employs various methods for information services arid, in particular, electric power generation including nuclear with an assignment from the Japanese Government. Public information activities by the Nuclear Power Engineering Corporation (NUPEC) are as follows: a) Telephone QA service to respond to public inquiries; b) Publishing the 'Nuclear Newsletter' monthly and various brochures; c) Information service by personal computer network Atomnet concerning energy in general, and operation/trouble informations of nuclear plants; d) Distribution and service of personal computers to local governments offices/museums, etc., for users ranging from children to adults to gather nuclear related information; e) Organization of female monitors 'ENE-MATES' to have lecture meetings and site tours. ENE-MATES - A Public Information Program For Women. As a 1990 opinion poll shows, women's feelings about nuclear energy differ from that of men. Women are more sensitive and anxious than men on nuclear energy issues. To improve this situation several programs for women have been planned and implemented.'ENE-MATES' program is one of these cases. It's purpose is to encourage women, centering around house wives, to have unbiased understanding of energy-related issues

  14. On the reaction of the nitroso group with olefins. Mechanisms of ene reactions

    Seymour, C.A.; Greene, F.D.

    1982-01-01

    Intra- and intermolecular isotope effects point to a two-step process for the reaction of pentafluoronitrosobenzene with tetramethylethylene to afford the ene product, rate-determining formation of an intermediate (for which the arizidine N-oxide is suggested) followed by C-H (or C-D) cleavage to the ene product

  15. Novel Thiol-Ene Hybrid Coating for Metal Protection

    Mona Taghavikish

    2016-04-01

    Full Text Available A novel hybrid anticorrosion coating with dual network of inorganic (Si–O–Si and organic bonds (C–S–C was prepared on metal through an in situ sol-gel and thiol-ene click reaction. This novel interfacial thin film coating incorporates (3-mercaptopropyl trimethoxysilane (MPTS and 1,4-di(vinylimidazolium butane bisbromide based polymerizable ionic liquid (PIL to form a thiol-ene based photo-polymerized film, which on subsequent sol-gel reaction forms a thin hybrid interfacial layer on metal surface. On top of this PIL hybrid film, a self-assembled nanophase particle (SNAP coating was employed to prepare a multilayer thin film coating for better corrosion protection and barrier performance. The novel PIL hybrid film was characterised for structure and properties using Fourier transform infrared spectroscopy (FTIR, differential scanning calorimetry (DSC, and thermogravimetric analysis (TGA. The corrosion protection performance of the multilayer coating was examined using potentiodynamic polarization and electrochemical impedance spectroscopy (EIS. The results reveal that this novel double layer coating on metal offers excellent protection against corrosion and has remarkably improved the barrier effect of the coating.

  16. Continuous Flow Science in an Undergraduate Teaching Laboratory: Photocatalytic Thiol-Ene Reaction Using Visible Light

    Santandrea, Jeffrey; Kairouz, Vanessa; Collins, Shawn K.

    2018-01-01

    An undergraduate teaching laboratory experiment involving a continuous flow, photocatalytic thiol-ene reaction using visible-light irradiation is described that allows students to explore concepts of green chemistry, photochemistry, photocatalysis, and continuous flow chemistry.

  17. Investigations of thiol-modified phenol derivatives for the use in thiol–ene photopolymerizations

    Sebastian Reinelt; Monir Tabatabai; Urs Karl Fischer; Norbert Moszner; Andreas Utterodt; Helmut Ritter

    2014-01-01

    Summary Thiol–ene photopolymerizations gain a growing interest in academic research. Coatings and dental restoratives are interesting applications for thiol–ene photopolymerizations due to their unique features. In most studies the relative flexible and hydrophilic ester derivative, namely pentaerythritoltetra(3-mercaptopropionate) (PETMP), is investigated as the thiol component. Thus, in the present study we are encouraged to investigate the performance of more hydrophobic ester-free thiol-m...

  18. Draama 2007. Töörahu / Ene Paaver

    Paaver, Ene, 1963-

    2008-01-01

    Ülevaade 2007. aasta eesti draamast. Pikemalt käsitletakse järgmisi autoreid ja nende näidendeid: Mart Kivastik "Tõnu võitlused", Mart Kivastik "Eesti asi", Mart Kivastik "Sõdur", Mart Kivastik "Kuninga viimane lahing ja ülikooli algus", Mart Kivastik, "Nokia 3310", Andrus Kivirähk "Voldemar", Andrus Kivirähk "Uljas neitsi", Hendrik Toompere "Kommunisti surm", Andres Ehin "Saatuslik kihlvedu ehk Volquin Varbola all", Jan Rahman "Jõujaam", Jaak Kõdar "Muinassaar", Karl Berg "Teekond valguse riiki", Angela Randmets "Lembelood vanas linnas", Toomas Kall "Tähtede sadu", Lauri Vahtre "Muna EÜE", Urmas Espenberg "Kestvad kiiduavaldused", Kalju Saaber "Koduvõõrad", Indrek Hirv "Pauluse kiriku kellad", Katrin Saukas "Võlg", Heidi Sarapuu "Austatud Riigikogu liikmed!", Heidi Sarapuu "Helisev viis", Heidi Sarapuu "Ankur hiivata", Jakob Karu "Vanaema juures", Jim Ashilevi "Nagu poisid vihma käes", Jim Ashilevi "Portselansuits", Eva Koff "Mirr", Jaak Prints "Karaoke", Kati Murutar "Mina, naine!", Ott Aardam "Börs ja Börsitar", Andrus Kivirähk, Jan Rahman, Contra "Kõrts", Mart Kase "Perekond", Villu Tamme "Haned võlgu"; Tiit Ojasoo ja Ene-Liis Semperi "GEP ehk Gorjatshije estonskije parni"

  19. Simple preparation of thiol-ene particles in glycerol and surface functionalization by thiol-ene chemistry (TEC) and surface chain transfer free radical polymerization (SCT-FRP)

    Hoffmann, Christian; Chiaula, Valeria; Yu, Liyun

    2018-01-01

    functionalization of excess thiol groups via photochemical thiol-ene chemistry (TEC) resulting in a functional monolayer. In addition, surface chain transfer free radical polymerization (SCT-FRP) was used for the first time to introduce a thicker polymer layer on the particle surface. The application potential...

  20. Ene-Liis Semper : hindan päeva, kui teen ühte asja / Ene-Liis Semper ; interv. Jaanus Kulli

    Semper, Ene-Liis, 1969-

    2008-01-01

    Teatri- ja videokunstnik Ene-Liis Semper oma elust ja tööst. Lisaks repliik "Parim päev on tööst prii päev" ja peagi Teater NO99s esietenduvast William Shakespeare'i lavastusest "Muinasjutuline "Perikles"

  1. Preparation and Preliminary Dielectric Characterization of Structured C60-Thiol-Ene Polymer Nanocomposites Assembled Using the Thiol-Ene Click Reaction

    Hanaa M. Ahmed

    2015-11-01

    Full Text Available Fullerene-containing materials have the ability to store and release electrical energy. Therefore, fullerenes may ultimately find use in high-voltage equipment devices or as super capacitors for high electric energy storage due to this ease of manipulating their excellent dielectric properties and their high volume resistivity. A series of structured fullerene (C60 polymer nanocomposites were assembled using the thiol-ene click reaction, between alkyl thiols and allyl functionalized C60 derivatives. The resulting high-density C60-urethane-thiol-ene (C60-Thiol-Ene networks possessed excellent mechanical properties. These novel networks were characterized using standard techniques, including infrared spectroscopy (FTIR, differential scanning calorimetry (DSC, dynamic mechanical analysis (DMA, and thermal gravimetric analysis (TGA. The dielectric spectra for the prepared samples were determined over a broad frequency range at room temperature using a broadband dielectric spectrometer and a semiconductor characterization system. The changes in thermo-mechanical and electrical properties of these novel fullerene-thiol-ene composite films were measured as a function of the C60 content, and samples characterized by high dielectric permittivity and low dielectric loss were produced. In this process, variations in chemical composition of the networks were correlated to performance characteristics.

  2. Rapid and simple preparation of thiol-ene emulsion-templated monoliths and their application as enzymatic microreactors

    Lafleur, Josiane P; Senkbeil, Silja; Novotny, Jakub

    2015-01-01

    A novel, rapid and simple method for the preparation of emulsion-templated monoliths in microfluidic channels based on thiol-ene chemistry is presented. The method allows monolith synthesis and anchoring inside thiol-ene microchannels in a single photoinitiated step. Characterization by scanning...... electron microscopy showed that the methanol-based emulsion templating process resulted in a network of highly interconnected and regular thiol-ene beads anchored solidly inside thiol-ene microchannels. Surface area measurements indicate that the monoliths are macroporous, with no or little micro...

  3. Aasta betoonehitise žürii kommentaarid võistlustöödele ja võitjaile / Eva Kiisler, Maritta Koivisto, Angel Andla...[jt.] ; intervjueerinud Mari Sarv ; kommenteerinud Mart Riikoja

    2009-01-01

    Konkursile "Aasta Betoonehitis 2008" annavad hinnangu Eva Kiisler (ajakirja "Ehitaja" peatoimetaja), Maritta Koivisto (Soome ajakirja "Betoni" peatoimetaja"), Angel Andla (Eesti Ehitusettevõtjate Liit), Heiki Meos (Eesti Ehitusinseneride Liit), Siim Sultson ("Äripäeva" ehitusvaldkonna toimetaja), Toomas Laur (Eesti Betooniühing), Ike Volkov (Eesti Arhitektide Liidu esimees), Mauno Inkinen (Eesti Projektbüroode Liit), Enno Rebane (Eesti Ehitusmaterjalide Tootjate Liidu tegevdirektor). Mart Riikoja žürii tööst

  4. Investigations of thiol-modified phenol derivatives for the use in thiol-ene photopolymerizations.

    Reinelt, Sebastian; Tabatabai, Monir; Fischer, Urs Karl; Moszner, Norbert; Utterodt, Andreas; Ritter, Helmut

    2014-01-01

    Thiol-ene photopolymerizations gain a growing interest in academic research. Coatings and dental restoratives are interesting applications for thiol-ene photopolymerizations due to their unique features. In most studies the relative flexible and hydrophilic ester derivative, namely pentaerythritoltetra(3-mercaptopropionate) (PETMP), is investigated as the thiol component. Thus, in the present study we are encouraged to investigate the performance of more hydrophobic ester-free thiol-modified bis- and trisphenol derivatives in thiol-ene photopolymerizations. For this, six different thiol-modified bis- and trisphenol derivatives exhibiting four to six thiol groups are synthesized via the radical addition of thioacetic acid to suitable allyl-modified precursors and subsequent hydrolysis. Compared to PETMP better flexural strength and modulus of elasticity are achievable in thiol-ene photopolymerizations employing 1,3,5-triallyl-1,3,5-triazine-2,4,6-trione (TATATO) as the ene derivative. Especially, after storage in water, the flexural strength and modulus of elasticity is twice as high compared to the PETMP reference system.

  5. Investigations of thiol-modified phenol derivatives for the use in thiol–ene photopolymerizations

    Reinelt, Sebastian; Tabatabai, Monir; Fischer, Urs Karl; Moszner, Norbert; Utterodt, Andreas

    2014-01-01

    Summary Thiol–ene photopolymerizations gain a growing interest in academic research. Coatings and dental restoratives are interesting applications for thiol–ene photopolymerizations due to their unique features. In most studies the relative flexible and hydrophilic ester derivative, namely pentaerythritoltetra(3-mercaptopropionate) (PETMP), is investigated as the thiol component. Thus, in the present study we are encouraged to investigate the performance of more hydrophobic ester-free thiol-modified bis- and trisphenol derivatives in thiol–ene photopolymerizations. For this, six different thiol-modified bis- and trisphenol derivatives exhibiting four to six thiol groups are synthesized via the radical addition of thioacetic acid to suitable allyl-modified precursors and subsequent hydrolysis. Compared to PETMP better flexural strength and modulus of elasticity are achievable in thiol–ene photopolymerizations employing 1,3,5-triallyl-1,3,5-triazine-2,4,6-trione (TATATO) as the ene derivative. Especially, after storage in water, the flexural strength and modulus of elasticity is twice as high compared to the PETMP reference system. PMID:25161731

  6. Investigations of thiol-modified phenol derivatives for the use in thiol–ene photopolymerizations

    Sebastian Reinelt

    2014-07-01

    Full Text Available Thiol–ene photopolymerizations gain a growing interest in academic research. Coatings and dental restoratives are interesting applications for thiol–ene photopolymerizations due to their unique features. In most studies the relative flexible and hydrophilic ester derivative, namely pentaerythritoltetra(3-mercaptopropionate (PETMP, is investigated as the thiol component. Thus, in the present study we are encouraged to investigate the performance of more hydrophobic ester-free thiol-modified bis- and trisphenol derivatives in thiol–ene photopolymerizations. For this, six different thiol-modified bis- and trisphenol derivatives exhibiting four to six thiol groups are synthesized via the radical addition of thioacetic acid to suitable allyl-modified precursors and subsequent hydrolysis. Compared to PETMP better flexural strength and modulus of elasticity are achievable in thiol–ene photopolymerizations employing 1,3,5-triallyl-1,3,5-triazine-2,4,6-trione (TATATO as the ene derivative. Especially, after storage in water, the flexural strength and modulus of elasticity is twice as high compared to the PETMP reference system.

  7. Surface modification of cyclomatrix polyphosphazene microsphere by thiol-ene chemistry and lectin recognition

    Chen, Chen; Zhu, Xue-yan; Gao, Qiao-ling; Fang, Fei; Huang, Xiao-jun

    2016-01-01

    Graphical abstract: A new synthetic route leading to polyphosphazene cyclomatrix microsphere with various functional groups has achieved via thiol-ene click modification. Herein, hexacholorocyclophosphazene (HCCP) crosslinked with bisphenol-S and 4,4′-diallyl bisphenol-S to generate broadly dispersed microspheres. Thiol-ene modification under UV irradiation not only presented high efficiency and flexibility for post-functionalization, but also imposed no harm on global morphology and crosslinked skeleton of such microspheres. - Highlights: • Functional polyphosphazene microspheres with high chemical flexibility were synthesized by thiol-ene modification. • Polyphosphazene microspheres possessed high thermal stability. • Glycosylated polyphosphazene microspheres showed affinity to lectin Con-A, which inferred potential application in biomedicine. - Abstract: A new synthetic route leading to functional polyphosphazene cyclomatrix microsphere has been developed via thiol-ene click modification. Hexacholorocyclophosphazene (HCCP) was crosslinked with both bisphenol-S and 4,4′-diallyl bisphenol-S to obtain vinyl polyphosphazene microspheres (VPZM) in order to ensure high crosslinking degree and introduce vinyl moieties. Compared to the microspheres obtained by HCCP and bisphenol-S, the size of VPZM was broadly dispersed from 400 nm to 1.40 μm. Thiol-ene click reactions were carried out to attach functional groups, such as glucosyl, carboxyl, ester and dodecyl groups onto polyphosphazene microspheres, which demonstrated no change in morphology and size after modification. Solid state NMR (SSNMR) and Fourier transform infrared spectoscopy (FT-IR) results showed that the vinyl moieties were introduced in the period of crosslinking and functionalization was also successful via click reactions. Moreover, the microspheres presented a little difference in thermal properties after modification. Concanavalin A (Con-A) fluorescent adsorption was also observed for

  8. Surface modification of cyclomatrix polyphosphazene microsphere by thiol-ene chemistry and lectin recognition

    Chen, Chen; Zhu, Xue-yan; Gao, Qiao-ling; Fang, Fei; Huang, Xiao-jun, E-mail: hxjzxh@zju.edu.cn

    2016-11-30

    Graphical abstract: A new synthetic route leading to polyphosphazene cyclomatrix microsphere with various functional groups has achieved via thiol-ene click modification. Herein, hexacholorocyclophosphazene (HCCP) crosslinked with bisphenol-S and 4,4′-diallyl bisphenol-S to generate broadly dispersed microspheres. Thiol-ene modification under UV irradiation not only presented high efficiency and flexibility for post-functionalization, but also imposed no harm on global morphology and crosslinked skeleton of such microspheres. - Highlights: • Functional polyphosphazene microspheres with high chemical flexibility were synthesized by thiol-ene modification. • Polyphosphazene microspheres possessed high thermal stability. • Glycosylated polyphosphazene microspheres showed affinity to lectin Con-A, which inferred potential application in biomedicine. - Abstract: A new synthetic route leading to functional polyphosphazene cyclomatrix microsphere has been developed via thiol-ene click modification. Hexacholorocyclophosphazene (HCCP) was crosslinked with both bisphenol-S and 4,4′-diallyl bisphenol-S to obtain vinyl polyphosphazene microspheres (VPZM) in order to ensure high crosslinking degree and introduce vinyl moieties. Compared to the microspheres obtained by HCCP and bisphenol-S, the size of VPZM was broadly dispersed from 400 nm to 1.40 μm. Thiol-ene click reactions were carried out to attach functional groups, such as glucosyl, carboxyl, ester and dodecyl groups onto polyphosphazene microspheres, which demonstrated no change in morphology and size after modification. Solid state NMR (SSNMR) and Fourier transform infrared spectoscopy (FT-IR) results showed that the vinyl moieties were introduced in the period of crosslinking and functionalization was also successful via click reactions. Moreover, the microspheres presented a little difference in thermal properties after modification. Concanavalin A (Con-A) fluorescent adsorption was also observed for

  9. Evaluation and Control of Thiol-ene/Thiol-epoxy Hybrid Networks

    Carioscia, Jacquelyn A.; Stansbury, Jeffrey W.; Bowman, Christopher N.

    2007-01-01

    The development of thiol-ene/thiol-epoxy hybrid networks offers the advantage of tailorable polymerization kinetics while producing a highly crosslinked, high Tg polymer that has significantly reduced shrinkage stress. Stoichiometric mixtures of pentaerythritol tetra(3-mercaptopropionate) (PETMP)/triallyl-1,3,5-triazine-2,4,6-trione (TATATO) (thiol-ene, mixture 1) and PETMP/bisphenol a diglycidyl ether (BADGE) (thiol-epoxy, mixture 2) were prepared and hybrid mixtures of 75/25, 50/50, 25/75, ...

  10. Fabrication of Biomolecule Microarrays Using Rapid Photochemical Surface Patterning in Thiol-Ene-Based Microfluidic Devices.

    Jönsson, Alexander; Lafleur, Josiane P

    2018-01-01

    In many biochip applications, it is advantageous to be able to immobilize biomolecules at specific locations on the surface of solid supports. In this protocol, we describe a photochemical surface patterning procedure based on thiol-ene/yne photochemistry which allows for the simple and rapid selective patterning of biomolecules on thiol-ene solid supports. We describe the preparation of solid supports which are required for the immobilization, including porous monoliths, as well as two different immobilization schemes based on biotin-streptavidin interactions and covalent linkage via free amino groups respectively.

  11. Preparation and Characterization of Fluorinated Hydrophobic UV-Crosslinkable Thiol-Ene Polyurethane Coatings

    Wenjing Xia

    2017-08-01

    Full Text Available The polyurethane prepolymer terminated with a double bond was synthesized using isophorone diisocyanate (IPDI, hydroxyl terminated polybutadiene (HTPB, 1,4-butanediol (BDO, and 2-hydroxyethyl acrylate (HEA. Then, a series of innovative UV-curable polyurethane coatings were prepared by blending ene-terminated polyurethane, fluoroacrylate monomer, and multifunctional thiol crosslinker upon UV exposure. The incorporation of fluoroacrylate monomer and multifunctional thiols into polyurethane coatings significantly enhanced the hydrophobic property, mechanical property, pencil hardness, and glossiness of the polyurethane coatings. This method of preparing UV crosslinkable, hydrophobic polyurethane coatings based on thiol-ene chemistry exhibited numerous advantages over other UV photocuring systems.

  12. Episodic nature of the delta 4-ene and delta 5-ene steroidogenic pathways and their relationship to the adreno-gonadal axis in stallions.

    Ganjam, V K

    1979-01-01

    Changes in the daily secretory patterns of testosterone and other 17 beta-hydroxyandrogen, total oestrogens and total corticoids were investigated in 7 stallions. Pulsatile fluctuations in plasma hormone levels were found in the serial blood samples collected hourly for 24 h in all animals. The plasma profiles indicated that corticoids, oestrogens and androgens were secreted episodically at all times in stallions. A significant correlation was observed between the precursor and products of delta 4-ene and delta 5-ene pathways and in inverse correlation (r = -0.68; P less than 0.01) was observed between total androgens and total corticoids. The significance of these episodic fluctuations of the major steroid hormones are discussed.

  13. Patterned Hydrophilization of Nanoporous 1,2‐PB by Thiol‐ene Photochemistry

    Berthold, Anton; Sagar, Kaushal Shashikant; Ndoni, Sokol

    2011-01-01

    is monitored by FT‐IR, UV–Vis, contact angle, and gravimetry. Overall quantum yields are calculated for the two thiol‐ene “click” reactions in nano‐confinement, neatly revealing their chain‐like nature. Top–down photolithographic patterning is demonstrated, realizing hydrophilic nanoporous “corridors...

  14. DFT Investigation of the Palladium-Catalyzed Ene-Yne Coupling

    Henriksen, Signe Teuber; Tanner, David Ackland; Skrydstrup, T.

    2010-01-01

    ). Concerning chemoselectivity, the calculations also clarify why the ene-yne coupling is able to dominate over plausible alternative reaction pathways such as alkene homocoupiing and alkyne polymerization. The role of the phosphine ligand at various stages of the catalytic cycle has also been delineated....

  15. Evaluation and Control of Thiol-ene/Thiol-epoxy Hybrid Networks.

    Carioscia, Jacquelyn A; Stansbury, Jeffrey W; Bowman, Christopher N

    2007-03-08

    The development of thiol-ene/thiol-epoxy hybrid networks offers the advantage of tailorable polymerization kinetics while producing a highly crosslinked, high T(g) polymer that has significantly reduced shrinkage stress. Stoichiometric mixtures of pentaerythritol tetra(3-mercaptopropionate) (PETMP)/triallyl-1,3,5-triazine-2,4,6-trione (TATATO) (thiol-ene, mixture 1) and PETMP/bisphenol a diglycidyl ether (BADGE) (thiol-epoxy, mixture 2) were prepared and hybrid mixtures of 75/25, 50/50, 25/75, and 10/90 w/w of mixtures 1 and 2 were polymerized using a combination of both radical and anionic initiation. The light exposure timing and the relative initiation conditions of the two types were used to control the order and relative rates of the radical and anionic polymerizations. The 50/50 w/w thiol-ene/thiol-epoxy hybrid material exhibited a final stress of only 0.2 MPa, which is 90 % lower than the stress developed in a control dimethacrylate resin. Kinetic analysis indicates composition affects network development in thiol-ene/thiol-epoxy hybrid networks and produces materials with robust mechanical properties.

  16. Efforts toward rapid construction of the cortistatin A carbocyclic core via enyne-ene metathesis

    Baumgartner, Corinne

    2010-01-01

    Our efforts toward the construction of the carbocylic core of cortistatin A via an enyne-ene metathesis are disclosed. Interestingly, an attempted S N2 inversion of a secondary mesylate in our five-membered D-ring piece gave a product with retention of stereochemistry. © 2010 The Royal Society of Chemistry.

  17. Preparation of Biomolecule Microstructures and Microarrays by Thiol–ene Photoimmobilization

    Weinrich, Dirk; Köhn, Maja; Jonkheijm, Pascal; Westerlind, Ulrika; Dehmelt, Leif; Engelkamp, Hans; Christianen, Peter C.M.; Kuhlmann, Jürgen; Maan, Jan C.; Nüsse, Dirk; Schröder, Hendrik; Wacker, Ron; Voges, Edgar; Breinbauer, Rolf; Kunz, Horst; Niemeyer, Christof M.; Waldmann, Herbert

    2010-01-01

    A mild, fast and flexible method for photoimmobilization of biomolecules based on the light-initiated thiol–ene reaction has been developed. After investigation and optimization of various surface materials, surface chemistries and reaction parameters, microstructures and microarrays of biotin,

  18. Rapid photochemical surface patterning of proteins in thiol-ene based microfluidic devices

    Lafleur, Josiane P.; Kwapiszewski, Radoslaw; Jensen, Thomas Glasdam

    2013-01-01

    ! 17 SH nm"2. Biotin alkyne was patterned directly inside thiol–ene microchannels prior to conjugation with fluorescently labelled streptavidin. The surface bound conjugates were detected by evanescent waveinduced fluorescence (EWIF), demonstrating the success of the grafting procedure and its...

  19. Rapid photochemical surface patterning of proteins in thiol-ene based microfluidic devices

    Lafleur, Josiane P.; Kwapiszewski, Radoslaw; Jensen, Thomas Glasdam

    2012-01-01

    ” and “ene” monomers present in the microfluidic chip bulk material provides a simple and efficient way of tuning the chip’s surface chemistry. Here, thiol-ene chips displaying an excess of functional thiol groups at their surfaces are functionalized with biotin and streptavidin in a controlled fashion using...

  20. Orented immobilization of farnesylated proteins by the thiol-ene reaction

    Weinrich, Dirk; Lin, Po-Chiao; Jonkheijm, Pascal; Nguyen, Uyen T.T.; Schröder, Hendrik; Niemeyer, Christof M.; Alexandrov, Kirill; Goody, Roger; Waldmann, Herbert

    2010-01-01

    Anchoring the protein: Proteins were immobilized rapidly under mild conditions by thiol-ene photocoupling between S-farnesyl groups attached to a genetically encodable “CAAX-box” tetrapeptide sequence (A is aliphatic) at the C terminus of the protein and surface-exposed thiols (see scheme). This

  1. Efforts toward rapid construction of the cortistatin A carbocyclic core via enyne-ene metathesis

    Baumgartner, Corinne; Ma, Sandy; Liu, Qi; Stoltz, Brian M.

    2010-01-01

    Our efforts toward the construction of the carbocylic core of cortistatin A via an enyne-ene metathesis are disclosed. Interestingly, an attempted S N2 inversion of a secondary mesylate in our five-membered D-ring piece gave a product with retention

  2. Heat- and light-induced thiol-ene oligomerization of soybean oil-based polymercaptan

    Polymercaptanized soybean oil (PMSO), the product of a thiol-ene reaction between soybean oil and hydrogen sulfide, is a material of interest as a lubricant additive and polymer precursor. We investigated with gel permeation chromatography, nuclear magnetic resonance (one-dimensional and two-dimensi...

  3. Functionalization of embedded thiol-ene waveguides for evanescent wave induced fluorescence detection in a microfluidic device

    Feidenhans'l, Nikolaj Agentoft; Jensen, Thomas Glasdam; Lafleur, Josiane P.

    2013-01-01

    We demonstrate the use of functional surface groups inherently present on off-stoichiometric thiol−ene polymers, for site-specific immobilization of biomolecules and detection by evanescent wave-induced fluorescence. An optofluidic chip featuring an embedded thiol−ene waveguide was selectively...... functionalized with biotin using photografting. The biotin was used for immobilization of fluorescently labelled streptavidin, and experiments revealed a linear correlation between streptavidin concentration and fluorescent intensity. To further demonstrate the attractiveness of using thiol−ene for optofluidic...

  4. A Study of Functional Polymer Colloids Prepared Using Thiol-Ene/Yne Click Chemistry

    Durham, Olivia Z.

    This project demonstrates the first instance of thiol-ene chemistry as the polymerization method for the production of polymer colloids in two-phase heterogeneous suspensions, miniemulsions, and emulsions. This work was also expanded to thiol-yne chemistry for the production of polymer particles containing increased crosslinking density. The utility of thiol-ene and thiol-yne chemistries for polymerization and polymer modification is well established in bulk systems. These reactions are considered 'click' reactions, which can be defined as processes that are both facile and simple, offering high yields with nearly 100% conversion, no side products, easy product separation, compatibility with a diverse variety of commercially available starting materials, and orthogonality with other chemistries. In addition, thiol-ene and thiol-yne chemistry follow a step-growth mechanism for the development of highly uniform polymer networks, where polymer growth is dependent on the coupling of functional groups. These step-growth polymerization systems are in stark contrast to the chain-growth mechanisms of acrylic and styrenic monomers that have dominated the field of conventional heterogeneous polymerizations. Preliminary studies evaluated the mechanism of particle production in suspension and miniemulsion systems. Monomer droplets were compared to the final polymer particles to confirm that particle growth occurred through the polymerization of monomer droplets. Additional parameters examined include homogenization energy (mechanical mixing), diluent species and concentration, and monomer content. These reactions were conducted using photoinitiation to yield particles in a matter of minutes with diameters in the size range of several microns to hundreds of microns in suspensions or submicron particles in miniemulsions. Improved control over the particle size and size distribution was examined through variation of reaction parameters. In addition, a method of seeded suspension

  5. Superhydrophobic hybrid inorganic-organic thiol-ene surfaces fabricated via spray-deposition and photopolymerization.

    Sparks, Bradley J; Hoff, Ethan F T; Xiong, Li; Goetz, James T; Patton, Derek L

    2013-03-13

    We report a simple and versatile method for the fabrication of superhydrophobic inorganic-organic thiol-ene coatings via sequential spray-deposition and photopolymerization under ambient conditions. The coatings are obtained by spray-deposition of UV-curable hybrid inorganic-organic thiol-ene resins consisting of pentaerythritol tetra(3-mercaptopropionate) (PETMP), triallyl isocyanurate (TTT), 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane (TMTVSi), and hydrophobic fumed silica nanoparticles. The spray-deposition process and nanoparticle agglomeration/dispersion provide surfaces with hierarchical morphologies exhibiting both micro- and nanoscale roughness. The wetting behavior, dependent on the concentration of TMTVSi and hydrophobic silica nanoparticles, can be varied over a broad range to ultimately provide coatings with high static water contact angles (>150°), low contact angle hysteresis, and low roll off angles (spray-deposition and UV-cure process on a variety of substrate surfaces including glass, paper, stone, and cotton fabric.

  6. Ene-Liis Semper : Kohalolu piiritsoonis = Presence in the border zone / Anu Allas

    Allas, Anu, 1977-

    2007-01-01

    Teatri- ja videokunstnik Ene-Liis Semperi peamiselt 1990-ndate aastate videotest, mis on valdavalt rõhutatult lavastuslikud, paisutatult sümbolistlikud või kus on esitatud piirsituatsioone, ahistust ning selle teadlikku eksponeerimist väljakutsena publikule. Iseennast paljastades, alandades ja ohtu seades jääb kunstnik enamasti jahedalt distantseerituks, publikule jääb aga arusaamatuks, kas tegemist on ohvri, kangelanna või osava mänguriga

  7. Heterofunctional Glycopolypeptides by Combination of Thiol-Ene Chemistry and NCA Polymerization.

    Krannig, Kai-Steffen; Schlaad, Helmut

    2016-01-01

    Glycopolypeptides are prepared either by the polymerization of glycosylated amino acid N-carboxyanhydrides (NCAs) or by the post-polymerization functionalization of polypeptides with suitable functional groups. Here we present a method for the in-situ functionalization and (co-) polymerization of allylglycine N-carboxyanhydride in a facile one-pot procedure, combining radical thiol-ene photochemistry and nucleophilic ring-opening polymerization techniques, to yield well-defined heterofunctional glycopolypeptides.

  8. Preparation and Characterization of Fluorinated Hydrophobic UV-Crosslinkable Thiol-Ene Polyurethane Coatings

    Wenjing Xia; Nianqing Zhu; Rongjie Hou; Wengui Zhong; Mingqing Chen

    2017-01-01

    The polyurethane prepolymer terminated with a double bond was synthesized using isophorone diisocyanate (IPDI), hydroxyl terminated polybutadiene (HTPB), 1,4-butanediol (BDO), and 2-hydroxyethyl acrylate (HEA). Then, a series of innovative UV-curable polyurethane coatings were prepared by blending ene-terminated polyurethane, fluoroacrylate monomer, and multifunctional thiol crosslinker upon UV exposure. The incorporation of fluoroacrylate monomer and multifunctional thiols into polyurethane ...

  9. Thiol-ene reaction as tool for crosslinking of polynorbornene micelles in the nanoscale

    Rupp, Barbara; Bauer, Thomas; Slugovc, Christian

    2009-08-01

    The thiol-ene reaction is a established photoreaction of multifunctional thiols and enes. Virtually any type of ene will participate in a free radical polymerisation process with a thiol. An advantage over many other photochemical reactions is that the reaction proceeds almost as rapidly in ambient conditions as in inert atmosphere. In this work we introduce the UV-crosslinking of polynorbornenes made by ring opening metathesis polymerization making use of the residual double bond in the polymer backbone. The crosslinking experiments were done in thin films and were followed by FTIR measurements, to proof the accessibility of double-bonds in the polymers for the addition of the thiols. As a result of these pre-experiments we created flexible and light transmitting films. To further increase the scope of this reaction, amphiphilic block copolymers were prepared and used to form block copolymer micelles in a selective solvent, which were subsequently crosslinked with pentaerythritol tetra(3-mercaptopropionate) (PETMP). FT-IR, DLS and SEM-measurements were used to prove the successful crosslinking and thus nanoparticle formation.

  10. Antibiofouling hybrid dendritic Boltorn/star PEG thiol-ene cross-linked networks.

    Bartels, Jeremy W; Imbesi, Philip M; Finlay, John A; Fidge, Christopher; Ma, Jun; Seppala, Jonathan E; Nystrom, Andreas M; Mackay, Michael E; Callow, James A; Callow, Maureen E; Wooley, Karen L

    2011-06-01

    A series of thiol-ene generated amphiphilic cross-linked networks was prepared by reaction of alkene-modified Boltorn polyesters (Boltorn-ene) with varying weight percent of 4-armed poly(ethylene glycol) (PEG) tetrathiol (0-25 wt%) and varying equivalents of pentaerythritol tetrakis(3-mercaptopropionate) (PETMP) (0-64 wt%). These materials were designed to present complex surface topographies and morphologies, with heterogeneity of surface composition and properties and robust mechanical properties, to serve as nontoxic antibiofouling coatings that are amenable to large-scale production for application in the marine environment. Therefore, a two-dimensional matrix of materials compositions was prepared to study the physical and mechanical properties, over which the compositions spanned from 0 to 25 wt% PEG tetrathiol and 0-64 wt% PETMP (the overall thiol/alkene (SH/ene) ratios ranged from 0.00 to 1.00 equiv), with both cross-linker weight percentages calculated with respect to the weight of Boltorn-ene. The Boltorn-ene components were prepared through the esterification of commercially available Boltorn H30 with 3-butenoic acid. The subsequent cross-linking of the Boltorn-PEG-PETMP films was monitored using IR spectroscopy, where it was found that near-complete consumption of both thiol and alkene groups occurred when the stoichiometry was ca. 48 wt% PETMP (0.75 equiv SH/ene, independent of PEG amount). The thermal properties of the films showed an increase in T(g) with an increase in 4-armed PEG-tetrathiol wt%, regardless of the PETMP concentration. Investigation of the bulk mechanical properties in dry and wet states found that the Young's modulus was the greatest at 48 wt% PETMP (0.75 equiv of SH/ene). The ultimate tensile strength increased when PETMP was constant and the PEG concentration was increased. The Young's modulus was slightly lower for wet films at constant PEG or constant PETMP amounts, than for the dry samples. The nanoscopic surface features were

  11. Advantages and drawbacks of Thiol-ene based resins for 3D-printing

    Leonards, Holger; Engelhardt, Sascha; Hoffmann, Andreas; Pongratz, Ludwig; Schriever, Sascha; Bläsius, Jana; Wehner, Martin; Gillner, Arnold

    2015-03-01

    The technology of 3D printing is conquering the world and awakens the interest of many users in the most varying of applications. New formulation approaches for photo-sensitive thiol-ene resins in combination with various printing technologies, like stereolithography (SLA), projection based printing/digital light processing (DLP) or two-photon polymerization (TPP) are presented. Thiol-ene polymerizations are known for its fast and quantitative reaction and to form highly homogeneous polymer networks. As the resins are locally and temporally photo-curable the polymerization type is very promising for 3D-printing. By using suitable wavelengths, photoinitiator-free fabrication is feasible for single- and two photon induced polymerization. In this paper divinyl ethers of polyethylene glycols in combination with star-shaped tetrathiols were used to design a simple test-system for photo-curable thiol-ene resins. In order to control and improve curing depth and lateral resolution in 3D-polymerization processes, either additives in chemical formulation or process parameters can be changed. The achieved curing depth and resolution limits depend on the applied fabrication method. While two-/multiphoton induced lithography offers the possibility of micron- to sub-micron resolution it lacks in built-up speed. Hence single-photon polymerization is a fast alternative with optimization potential in sub-10-micron resolution. Absorber- and initiator free compositions were developed in order to avoid aging, yellowing and toxicity of resulting products. They can be cured with UV-laser radiation below 300 nm. The development at Fraunhofer ILT is focusing on new applications in the field of medical products and implants, technical products with respect to mechanical properties or optical properties of 3D-printed objects. Recent process results with model system (polyethylene glycol divinylether/ Pentaerithrytol tetrakis (3-mercaptopropionat), Raman measurements of polymer conversion

  12. Investigations of step-growth thiol-ene polymerizations for novel dental restoratives.

    Lu, Hui; Carioscia, Jacquelyn A; Stansbury, Jeffery W; Bowman, Christopher N

    2005-12-01

    The goal of this work was to investigate the feasibility of formulating novel dental restorative materials that utilize a step-growth thiol-ene photopolymerization. Particularly, we are aiming to significantly reduce the polymerization shrinkage and shrinkage stress while retaining adequate physical properties as compared to current dimethacrylatre-based systems. The thiol-ene system is composed of a 4:3 molar mixture of triallyl-1,3,5-triazine-2,4,6-trione (TATATO) and pentaerythritol tetramercaptopropionate (PETMP). The simultaneous measurement of shrinkage stress and functional group conversion was performed. Solvent extraction of unreacted monomers and dynamic mechanical analysis on the polymer networks that were formed were also studied. Flexural strength was measured for both filled and unfilled PETMP/TATATO and Bis-GMA/TEGDMA systems. Photopolymerization of PETMP/TATATO occurs at a much higher rate, with the maximum polymerization rate six times faster, than Bis-GMA/TEGDMA cured under the identical conditions. The results from the simultaneous measurement of shrinkage stress and conversion showed that the onset of shrinkage stress coincides with the delayed gel point conversion, which is predicted to be 41% for the 3:4 stoichiometric PETMP/TATATO resin composition. The maximum shrinkage stress developed for PETMP/TATATO was about 0.4 MPa, which was only approximately 14% of the maximum shrinkage stress of the Bis-GMA/TEGDMA system. Adequate flexural strength and flexural modulus values were obtained for both filled and unfilled PETMP/TATATO systems. The dramatically reduced shrinkage stress, increased polymerization rate, significance increased functional group conversion, and decreased leachable species are all benefits for the use-of thiol-ene systems as potential dental restorative materials.

  13. Aasta betoonehitis 2002 / Enno Rebane

    Rebane, Enno, 1964-

    2003-01-01

    Betoonehitis 2002 - Tartu vangla, Kalle Rõõmuse Arhitektuuribüroo (projekteerija EstKONSULT, ehitaja AS Skanska EMV). Eriauhinnad: arhitektuurse lahenduse eest - Erki Valdre, Tuvi t. 12 korterelamud Tallinnas; projekteerijale - Eesti Projekt, Linnamäe hüdroelektrijaama taastamine (arhitekt Raine Karp); ehitusmaterjalitootjale - E-Betoonelement, STT katuseelement (Nefab Eesti AS pakenditehas, arhitektuurne lahendus - Tõnis Tarbe Arhitektuuribüroo)

  14. Peer Gynti tagasitulek / Hilve Rebane

    Rebane, Hilve, 1938-2012

    1999-01-01

    Arvustus: Ibsen, Henrik. Peer Gynt / tõlkinud Marie Under. 2. tr. Tallinn : Eesti Raamat, 1998. Ka "Peer Gynti" mõjutusi eesti kirjanduses: August Gailiti, Marie Underi, A. H. Tammsaare ja eriti Karl Ristikivi loomingus

  15. Seisuslikud kohtud : talurahvakohtud / Ilmar Rebane

    Rebane, Ilmar, 1907-2001

    1982-01-01

    Mõisniku kohus ja kodukari, adra- ehk haagikohus, sillakohus, mõisakohus, asehalduskord, alam-maakohus, alam- ja ülemkorrakohus, vallakohus, kihelkonnakohus, kihelkonna politseikohus, mõisapolitsei, kogukonnapolitsei, kreisikohus, ülem-talurahvakohus. Lisatud väljavõtteid regulatiivist "Iggaüks"

  16. Lastekasvatuseks parim riik / Marit Rebane

    Rebane, Marit

    2016-01-01

    2016. aasta aprillis avaldatud UNICEFi ettekandes võrreldakse laste heaolu 41 Euroopa Liidu ja OECD riigis. Kokku on võetud laste heaolu neljas valdkonnas: sissetulekud, hariduslik ja tervislik ebavõrdsus ning ebavõrdsus eluga rahulolus

  17. Korruptsiooni bioloogilised juured / Jaak Rebane

    Rebane, Jaak

    1999-01-01

    Kuritarvitusele aitavad viia inimese teatud omadused, nagu egoism, piiratus, ahnus, jultumus, tarbimismentaliteet, tõusiklikkus. Korrumptantsaab varumistungi ajel ebaeetilisest käitumisest hoopis positiivse emotsiooni

  18. Synergistic Diazo-OH Insertion/Conia-Ene Cascade Catalysis for the Stereoselective Synthesis of γ-Butyrolactones and Tetrahydrofurans.

    Hunter, Arianne C; Schlitzer, Steven C; Sharma, Indrajeet

    2016-11-02

    A novel and highly efficient diazo-OH insertion/Conia-ene cascade reaction of readily available homopropargylic acids and alcohols with diazo carbonyl compounds is described. The cascade reaction involves a synergistic Rh/Ag/Au catalyst cocktail and proceeds instantly with a variety of substituted diazo compounds and acids/alcohols to provide functionalized γ-butyrolactones and tetrahydrofurans with complete regio- and stereoselectivity. The unprecedented rate-enhancement, complete stereoselectivity, and the enabling of new Conia-ene cyclizations suggest a concerted [4+1]-cycloaddition reaction pathway under synergistic (Rh/Ag/Au)-catalysis conditions. © 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  19. Synthesis and characterization of thiol-ene functionalized siloxanes and evaluation of their polymerization kinetics, network properties, and dental applications

    Cole, Megan A.

    We explored formation-structure-property relationships in thiol-ene functionalized oligosiloxanes to create crosslinked networks. Specifically, nine oligomers were synthesized, three with thiol-functional silane repeats and three with allyl-functional silane repeats. Structural variations in each oligomer were systematically induced through the incorporation of non-reactive repeats bearing either diphenyl or di-n-octyl moieties, and the oligomer molecular weight was limited by the presence of monofunctional silane condensation species. The molecular weights and chain compositions of all oligomers were ascertained and subsequently used in the evaluation of network properties formed upon photopolymerization of thiol- and ene-functional reactants. Polymerization kinetics of the thiol-ene functionalized siloxanes were also investigated using photoinitiation owing to the spatial and temporal control afforded by this technique. In particular, the effects of the viscosity of the ene-functionalized oligomer and the degree of thiol functionalization on the observed polymerization rate were determined. Results showed that the speed of polymerization varied with changes to the rate-limiting step, which was heavily influenced by neighboring non-reactive functionalities. Moreover, the thiol-ene reaction was found to exhibity unimolecular termination exclusively in siloxane-based systems. Proposed use of the thiol-ene functionalized siloxane system as a dental impression material necessitated the development of a redox initiation scheme. Evaluation of the benzoylperoxide/dimethyl-p-toluidine redox pair in traditional systems showed bulk thiol-ene polymerizations comparable to photoinitiation with the added advantage of uninhibited depth control, as also demonstrated in small molecule thiol-ene coupling reactions initiated by this same redox system. Application of the redox pair to the siloxane system allowed for the viscoelastic properties as well as the feature replication

  20. Photocured thiol-ene based optical fluorescence sensor for determination of gold(III)

    Çubuk, Soner, E-mail: sonercubuk@marmara.edu.tr; Kahraman, Memet Vezir; Yetimoğlu, Ece Kök; Kenan, Sibel

    2014-02-17

    Graphical abstract: -- Highlights: •Photopolymerized fluorescence sensor for Au(III) analysis has been developed. •Preparation of polymeric sensor is simple and quick. •Fluorescence sensor used for analysis of Au(III) in real samples. -- Abstract: This study describes the preparation and the characterization of a new thiol-ene based polymeric fluorescence sensor by photo initiated polymerization of trimethylolpropane tris(3-mercaptopropionate), 2-hydroxyethylacrylate, and 2,4,6-triallyloxy-1,3,5-triazine which are used as monomers and also a photo initiator (2,2-dimethoxy-2-phenylacetophenone) for its usage as optical sensor for gold ions. The thiol-ene based polymeric membrane sensor was characterized by using attenuated total reflectance-fourier transform infrared spectroscopy (ATR-FTIR) and scanning electron microscopy (SEM). The response characteristics of the sensors including dynamic range, pH effect, response time, and the effect of foreign ions were investigated. Fluorescence spectra showed that the excitation/emission maxima of the membrane were at 379/425 nm, respectively.

  1. Preliminary Engineering Report contaminated groundwater seeps 317/319/ENE area

    1996-01-01

    When the Resource Conservation and Recovery Act Facility Investigation (RFI) in the 317/319/ENE Area of Argonne National Laboratory-East (ANL-E) was being completed, groundwater was discovered moving to the surface through a series of seeps. The seeps are located approximately 600 ft south of the ANL fence line in Waterfall Glen Forest Preserve. Samples of this water were collected and analyzed for selected parameters. Two of five seeps sampled were found to contain detectable levels of organic contaminants. Three chemical species were identified: chloroform (14-25 μg/L), carbon tetrachloride (56-340 μg/L), and tetrachloroethylene (3-6 μg/L). The other seeps did not contain detectable levels of volatile organic compounds (VOCs). The water issuing from these two contaminated seeps flows into a narrow ravine, where it is visible as a trickle of water flowing through sand and gravel deposits on the floor of the ravine. Approximately 100-ft downstream of the seep area, the contaminated water is no longer visible, having drained back into the soil in the bed of the ravine. Figure 1 shows the location of the 317/319/ENE Area in relation to the ANL-E site and the Waterfall Glen Forest Preserve

  2. Photocured thiol-ene based optical fluorescence sensor for determination of gold(III)

    Çubuk, Soner; Kahraman, Memet Vezir; Yetimoğlu, Ece Kök; Kenan, Sibel

    2014-01-01

    Graphical abstract: -- Highlights: •Photopolymerized fluorescence sensor for Au(III) analysis has been developed. •Preparation of polymeric sensor is simple and quick. •Fluorescence sensor used for analysis of Au(III) in real samples. -- Abstract: This study describes the preparation and the characterization of a new thiol-ene based polymeric fluorescence sensor by photo initiated polymerization of trimethylolpropane tris(3-mercaptopropionate), 2-hydroxyethylacrylate, and 2,4,6-triallyloxy-1,3,5-triazine which are used as monomers and also a photo initiator (2,2-dimethoxy-2-phenylacetophenone) for its usage as optical sensor for gold ions. The thiol-ene based polymeric membrane sensor was characterized by using attenuated total reflectance-fourier transform infrared spectroscopy (ATR-FTIR) and scanning electron microscopy (SEM). The response characteristics of the sensors including dynamic range, pH effect, response time, and the effect of foreign ions were investigated. Fluorescence spectra showed that the excitation/emission maxima of the membrane were at 379/425 nm, respectively

  3. Rapid and simple preparation of thiol–ene emulsion-templated monoliths and their application as enzymatic microreactors

    Lafleur, J. P.; Senkbeil, S.; Novotný, Jakub; Nys, G.; Bøgelund, N.; Rand, K. D.; Foret, František; Kutter, J. P.

    2015-01-01

    Roč. 15, č. 10 (2015), s. 2162-2172 ISSN 1473-0197 R&D Projects: GA ČR(CZ) GBP206/12/G014 Institutional support: RVO:68081715 Keywords : thiol-enes * mictoreactor * monolith * fabrication * proteins Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 5.586, year: 2015

  4. Kas erivajadustega lapsed saavad õigel ajal abi? / Ene Mägi, Urve Raudsepp-Alt, Ale Sprenk, Peeter Aas

    2009-01-01

    Küsimusele vastavad: Tallinna Ülikooli Kasvatusteaduste Instituudi eri- ja sotsiaalpedagoogika osakonna juhataja Ene Mägi, Tallinna Haridusameti üldhariduse osakonna peaspetsialist Urve Raudsepp-Alt, Krabi põhikooli direktor Ale Sprenk, Põlva Maavalitsuse haridus-, kultuuri- ja sotsiaalosakonna juhataja Peeter Aas

  5. Koolirõõmuta kool on lapsele kui sunnitöö / Ene-Silvia Sarv ; intervjueerinud Karin Klaus

    Sarv, Ene-Silvia, 1945-

    2013-01-01

    Intervjuu Pärnus hariduskonverentsil "Õnnelik õpilane, õnnelik õpetaja" esinenud Tallinna ülikooli lektori Ene-Silvia Sarvega, kes rääkis oma ettekandes, milline paistab tänapäeva kool õpilaste silme läbi ja mis mõjutab koolikliimat kõige enam

  6. Poly(ethylene glycol)-based thiol-ene hydrogel coatings: curing chemistry, aqueous stability, and potential marine antifouling applications

    Lundberg, P.; Bruin, A.; Klijnstra, J.W.; Nyström, A.M.; Johansson, M.; Malkoch, M.; Hult, A.

    2010-01-01

    Photocured thiol-ene hydrogel coatings based on poly(ethylene glycol) (PEG) were investigated for marine antifouling purposes. By varying the PEG length, vinylic end-group, and thiol cross-linker, a library of hydrogel coatings with different structural composition was efficiently accomplished, with

  7. High performance thiol-ene thermosets based on fully bio-based poly(limonene carbonate)s

    Li, C.; Johansson, M.; Sablong, R.J.; Koning, C.E.

    2017-01-01

    High glass transition temperature (Tg) thiol-ene networks (TENs) based on poly(limonene carbonate)s (PLCs), derived from orange oils and of potential degradability are described here. PLCs with moderate molecular weight were prepared by copolymerization of limonene oxide with CO2 and subsequent

  8. A Convergent Enantioselective Total Synthesis of (-)-Perhydrohistrionicotoxin with an Intramolecular Imino Ene-type Reaction as a Key Step

    Tanner, David Ackland; Hagberg, Lars

    1998-01-01

    A convergent enantioselective total synthesis of the neurotoxic spirocyclic alkaloid (-)-perhydrohistrionicotoxin (2) is described. A Lewis acid-mediated intramolecular imine ene-type reaction was used for the key spirocyclisation step (14 to 3, with 3 being obtained as a single diastereoisomer...

  9. Mida teie oma tervise heaks teete? / Ly Jagor, Ülle Mihhailova, Ene Pill, Katrin Käbin...[jt.

    2008-01-01

    Küsimusele vastavad Pärnu Õppenõustamiskeskuse psühholoog Ly Jagor, Maasika lasteaia juhataja asetäitja Ülle Mihhailova, Tallinna Perekeskuse ja Tähetorni lastekeskuse psühholoog Ene Pill, Tallinna Nõmme Noortemaja väikelaste ringijuht Katrin Käbin, Tääksi Põhikooli õpetaja Silva Kolk

  10. 1-Methoxy-3-o-tolylbicyclo[2.2.2]oct-5-ene-2,2-dicarbonitrile

    Orhan Büyükgüngör

    2009-09-01

    Full Text Available In the title compound, C18H18N2O, the cyclohexene and cyclohexane rings of the bicyclo[2.2.2]oct-5-ene unit adopt distorted boat conformations. In the crystal, molecules exist as C—H...N hydrogen-bonded centrosymmetric R22(14 dimers, which are further linked by C—H...π interactions.

  11. Thermal decomposition of lanthanides (III) and yttrium (III) solid complexes from ethyl ene diamine tetraacetic acid

    Mercadante, A.

    1991-01-01

    Solid state compounds of lanthanides (III) and yttrium derived from ethyl ene diamine tetraacetic acid were prepared from respective basic carbonates, that were neutralized with EDTA stoichiometry quantities. Complexometry with EDTA, thermogravimetry (TG), differential thermal analysis (DTA) and X-ray diffraction have been used in the study of these compounds. The results of complexometry with EDTA as well as TG and DTA curves bed to the stoichiometry of these compounds the following general formula is obeyed: H[Ln(EDTA]. n H 2 O. X-ray powder patterns of these compounds permitted to establish two isomorphous series. The DTA ant TG curves allowed us to study the dehydration process, the thermal stability and thermal decomposition of these compounds. (C.G.C.)

  12. 3-(2-Benzofuranyl)quinuclidin-2-ene derivatives: novel muscarinic antagonists.

    Nordvall, G; Sundquist, S; Johansson, G; Glas, G; Nilvebrant, L; Hacksell, U

    1996-08-16

    A series of 26 derivatives of the novel muscarinic antagonist 3-(2-benzofuranyl)quinuclidin-2-ene (1) has been synthesized and evaluated for muscarinic and antimuscarinic properties. The affinity of the compounds was determined by competition experiments in homogenates of cerebral cortex, heart, parotid gland, and urinary bladder from guinea pigs using (-)-[3H]-3-quinuclidinyl benzilate as the radioligand, and the antimuscarinic-potency was determined in a functional assay on isolated guinea pig urinary bladder using carbachol as the agonist. The 5-fluorobenzofuranyl derivative was slightly more potent than 1. The 7-bromo-substituted 8 displayed a 14-fold tissue selectivity ratio for muscarinic receptors in the cortex versus the parotid gland. Comparative molecular field analysis and quantitative structure-activity relationship models were developed for this series of substituted benzofuranyl derivatives.

  13. Inorganic-Organic Thiol-ene Coated Mesh for Oil/Water Separation.

    Chen, Qiyi; de Leon, Al; Advincula, Rigoberto C

    2015-08-26

    A highly efficient mesh for oil/water separation was fabricated by using a superhydrophobic and superoleophilic coating of thiol-ene hybrid, consisting of pentaerythritol tetra(3-mercaptopropionate) (PETMP), 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane (TMTVSi), and hydrophobic fumed silica nanoparticles, via a simple two-step fabrication process. Spray deposition and UV curing photopolymerization were sequentially performed, during which solvent evaporation provides microscale roughness while nanoparticle aggregation forms nanoscale roughness. The hierarchical morphologies were stabilized after UV curing photopolymerization. High contact angle (>150°) and low roll-off angle (<5°) were achieved due to the multiscale roughness structure of the hierarchical morphologies. These coatings also have excellent chemical resistance, as well as temperature and pH stability, after curing.

  14. Development of a thiol-ene based screening platform for enzyme immobilization demonstrated using horseradish peroxidase

    Hoffmann, Christian; Pinelo, Manuel; Woodley, John

    2017-01-01

    Efficient immobilization of enzymes on support surfaces requires an exact match between the surface chemistry and the specific enzyme. A successful match would normally be identified through time consuming screening of conventional resins in multiple experiments testing individual immobilization...... strategies. In this study we present a versatile strategy that largely expands the number of possible surface functionalities for enzyme immobilization in a single, generic platform. The combination of many individual surface chemistries and thus immobilization methods in one modular system permits faster...... functionalization by thiol-ene chemistry (TEC) resulted in the formation of a functional monolayer in each well, whereas, polymer surface grafts were introduced through surface chain transfer free radical polymerization (SCT-FRP). Enzyme immobilization on the modified surfaces was evaluated by using a rhodamine...

  15. Amino acid-incorporated polymer network by thiol-ene polymerization

    R. Yokose

    2015-08-01

    Full Text Available Triallyl L-alanine (A3A and triallyl L-phenylalanine (A3F were synthesized by reactions of L-alanine and L-phenylalanine with allyl bromide in the presence of sodium hydroxide, respectively. Thiol-ene thermal polymerization of A3A or A3F with pentaerythritol-based primary tetrathiol (pS4P or pentaerythritol-based secondary tetrathiol (S4P at allyl/SH 1/1 in the presence of 2,2'-azobis(isobutyronitrile produced an amino acid-incorporated polymer network (A3ApS4P, A3A-S4P or A3F-S4P. Although the thermally cured resins were homogeneous and flat films, the corresponding thiol-ene photopolymerization did not give a successful result. Degree of swelling for each thermally cured film in N,Ndimethylformamide was much higher than that in water. The glass transition and 5% weight loss temperatures (Tg and T5 of A3F-pS4P and A3F-S4P were higher than those of A3A-pS4P and A3A-S4P, respectively. Also, A3F-pS4P and A3F-S4P exhibited much higher tensile strengths and moduli than A3A-pS4P and A3A-S4P did, respectively. Consequently, A3FpS4P displayed the highest Tg (38.7°C, T5 (282.0°C, tensile strength (9.5 MPa and modulus (406 MPa among all the thermally cured resins.

  16. Hydrophobic thiol-ene surfaces fabricated via plasma activation and photo polymerization

    Champathet, P.; Ervithayasuporn, V.; Osotchan, T.; Dangtip, S.

    2017-09-01

    Alumina, such as glazed alumina for electrical insulator, operated in an open field subjects to a very harsh condition; resulting in lifetime shortening. Coating hydrophobic layer on alumina surface can help prolonging its lifetime. In this study, 25 ×25 mm alumina sheets were used as substrates. The hydrophobic composite polymers were prepared from (3-mercaptopropyl)trimethoxysilane(MPTMS), 2,4,6,8-tetramethyl-2,4,6,8tetravinylcyclotetra siloxane(TMTVSi), pentaerythritoltetra(3-mercaptopropionate)(PETMP), 2,2-dimethoxy-2-phe nylaceto phenone(photoinitiator) and heptadecafluorodecylmethacrylate(HEFDMA) via the thiol-ene reaction. The alumina sheets were first activated by dielectric-barrier discharge plasma to improve its adhesion. All the polymers were found to optimize at the ratio of (MPTMS:TMTVSi:PETMP:HDFDMA) to 4:2:1:2 for coating on the alumina substrate. To enhance polymerization, 2,2-dimethoxy-2-phenylaceto phenome was also used as a photoinitiator A proper mixing sequence in the thiol-ene reaction results in film with excellent surface retention after prolong soaking in solvent such as acetone. FTIR shows that S-H and C=C functional groups have significantly changed after photopolymerization and thermally cured. The static contact angle increase from mere 53.0°±1.5° of the uncoated substrate to 120.0°±1.2° after coating. SEM shows the film with clear appearance of a few-micron thick. Under AFM, the coated surface roughness was about 9.3 nm with evenly distributed spikes of a few nanometer in height. The cross-cut test also confirmed the film was very smooth and none of the square of the films detached.

  17. Hydrophobic Coatings by Thiol-Ene Click Functionalization of Silsesquioxanes with Tunable Architecture.

    Dirè, Sandra; Bottone, Davide; Callone, Emanuela; Maniglio, Devid; Génois, Isabelle; Ribot, François

    2017-08-08

    The hydrolysis-condensation of trialkoxysilanes under strictly controlled conditions allows the production of silsesquioxanes (SSQs) with tunable size and architecture ranging from ladder to cage-like structures. These nano-objects can serve as building blocks for the preparation of hybrid organic/inorganic materials with selected properties. The SSQs growth can be tuned by simply controlling the reaction duration in the in situ water production route (ISWP), where the kinetics of the esterification reaction between carboxylic acids and alcohols rules out the extent of organosilane hydrolysis-condensation. Tunable SSQs with thiol functionalities (SH-NBBs) are suitable for further modification by exploiting the simple thiol-ene click reaction, thus allowing for modifying the wettability properties of derived coatings. In this paper, coatings were prepared from SH-NBBs with different architecture onto cotton fabrics and paper, and further functionalized with long alkyl chains by means of initiator-free UV-induced thiol-ene coupling with 1-decene (C10) and 1-tetradecene (C14). The coatings appeared to homogeneously cover the natural fibers and imparted a multi-scale roughness that was not affected by the click functionalization step. The two-step functionalization of cotton and paper warrants a stable highly hydrophobic character to the surface of natural materials that, in perspective, suggests a possible application in filtration devices for oil-water separation. Furthermore, the purification of SH-NBBs from ISWP by-products was possible during the coating process, and this step allowed for the fast, initiator-free, click-coupling of purified NBBs with C10 and C14 in solution with a nearly quantitative yield. Therefore, this approach is an alternative route to get sol-gel-derived, ladder-like, and cage-like SSQs functionalized with long alkyl chains.

  18. Fabrication of antibody-loaded microgels using microfluidics and thiol-ene photoclick chemistry.

    Gregoritza, Manuel; Abstiens, Kathrin; Graf, Moritz; Goepferich, Achim M

    2018-06-01

    Reducing burst effects, providing controlled release, and safeguarding biologics against degradation are a few of several highly attractive applications for microgels in the field of controlled release. However, the incorporation of proteins into microgels without impairing stability is highly challenging. In this proof of concept study, the combination of microfluidics and thiol-ene photoclick chemistry was evaluated for the fabrication of antibody-loaded microgels with narrow size distribution. Norbornene-modified eight-armed poly(ethylene glycol) with an average molecular mass of 10,000 Da, 20,000 Da, or 40,000 Da were prepared as macromonomers for microgel formation. For functionalization, either hydrolytically cleavable ester or stable amide bonds were used. A microfluidic system was employed to generate precursor solution droplets containing macromonomers, the cross-linker dithiothreitol and the initiator Eosin-Y. Irradiation with visible light was used to trigger thiol-ene reactions which covalently cross-linked the droplets. For all bond-types, molecular masses, and concentrations gelation was very rapid (<20 s) and a plateau for the complex shear modulus was reached after only 5 min. The generated microgels had a rod-like shape and did not show considerable cellular toxicity. Stress conditions during the fabrication process were simulated and it could be shown that fabrication did not impair the activity of the model proteins lysozyme and bevacizumab. It was confirmed that the average hydrogel network mesh size was similar or smaller than the hydrodynamic diameter of bevacizumab which is a crucial factor for restricting diffusion and delaying release. Finally, microgels were loaded with bevacizumab and a sustained release over a period of 30 ± 4 and 47 ± 7 days could be achieved in vitro. Copyright © 2018 Elsevier B.V. All rights reserved.

  19. Ene-yne Cross-Metathesis for the Preparation of 2,3-Diaryl-1,3-dienes

    Meriem K. Abderrezak

    2017-11-01

    Full Text Available Ene-yne cross-metathesis from alkynes and ethylene is a useful method to produce substituted conjugated butadiene derivatives. If this method has been used with aliphatic alkynes, it has however never been used starting from diarylacetylenes as internal alkynes. We show that the ene-yne cross-metathesis catalyzed by the second generation Hoveyda ruthenium catalyst provides the 2,3-diarylbuta-1,3-dienes under 3 atm of ethylene at 100 °C. The scope and limitations of the reaction have been evaluated starting from unsymmetrical functionalized diarylacetylene derivatives hence leading to unsymmetrical 2,3-diarylbuta-1,3-dienes in a straightforward and environmentally acceptable manner.

  20. Emplazamiento hacia el ENE del manto de Los Reales (Alpujarrides occidentales: criterios estructurales y de petrofábrica

    Tubía, J. M.

    1984-08-01

    Full Text Available Los Reales nappe rests over Ojén nappe to the North of Sierra Alpujata. The nappe contact zone shows a intense plastic deformation with mylonitic rocks, The deformation decreases progressively going away from the contacto The structural study of footwall and hangingwall roen permits to attribute this deformation to the Los Reales nappe emplacement over that of Ojén. The foliation and stretching lineation distributions show a WSW-ENE shear direction. The mylonite microstructural characteristics and the enstatite crystalline preferred orientations in the basal peridotites give a mear sense in according that, Los Reales nappe is displaced, in their present position, from the WSW towards the ENE.

    El manto de Los Reales descansa sobre el manto de Ojén, al norte de Sierra Alpujata. La zona de contacto entre mantos exhibe una intensa deformación plástica con rocas miloníticas; la deformación disminuye progresivamente al alejarse del contacto. El estudio estructural de las rocas infra y suprayacentes al contacto permite atribuir esta deformación al emplazamiento del manto de Los Reales sobre el de Ojén. , Las distribuciones de la foliación y de la lineación, de estiramiento indican una dirección de cizallamiento WSW-ENE. Las características microestructurales de las milonitas y las orientaciones preferentes cristalinas de la enstatita en las peridotitas basales proporcionan un sentido de cizallamiento tal que el manto de Los Reales se ha desplazado, en su posición actual, desde el WSW hacia el ENE.

  1. ENED-GEM: A Conceptual Framework Model for Psychological Enjoyment Factors and Learning Mechanisms in Educational Games about the Environment

    Fjællingsdal, Kristoffer S.; Klöckner, Christian A.

    2017-01-01

    Based on a thorough review of psychological literature, this article seeks to develop a model of game enjoyment and environmental learning (ENvironmental EDucational Game Enjoyment Model, ENED-GEM) and delineate psychological processes that might facilitate learning and inspire behavioral change from educational games about the environment. A critically acclaimed digital educational game about environmental issues (Fate of the World by Red Redemption/Soothsayer Games) was used as a case study. Two hundred forty-nine reviews of the game from the popular gaming and reviewing platform known as Steam were analyzed by means of a thematic content analysis in order to identify key player enjoyment factors believed to be relevant to the process of learning from games, as well as to gain an understanding of positive and negative impressions about the game’s general content. The end results of the thematic analysis were measured up to the suggested ENED-GEM framework. Initial results generally support the main elements of the ENED-GEM, and future research into the importance of these individual core factors is outlined. PMID:28701988

  2. ENED-GEM: A Conceptual Framework Model for Psychological Enjoyment Factors and Learning Mechanisms in Educational Games about the Environment

    Kristoffer S. Fjællingsdal

    2017-06-01

    Full Text Available Based on a thorough review of psychological literature, this article seeks to develop a model of game enjoyment and environmental learning (ENvironmental EDucational Game Enjoyment Model, ENED-GEM and delineate psychological processes that might facilitate learning and inspire behavioral change from educational games about the environment. A critically acclaimed digital educational game about environmental issues (Fate of the World by Red Redemption/Soothsayer Games was used as a case study. Two hundred forty-nine reviews of the game from the popular gaming and reviewing platform known as Steam were analyzed by means of a thematic content analysis in order to identify key player enjoyment factors believed to be relevant to the process of learning from games, as well as to gain an understanding of positive and negative impressions about the game’s general content. The end results of the thematic analysis were measured up to the suggested ENED-GEM framework. Initial results generally support the main elements of the ENED-GEM, and future research into the importance of these individual core factors is outlined.

  3. ENED-GEM: A Conceptual Framework Model for Psychological Enjoyment Factors and Learning Mechanisms in Educational Games about the Environment.

    Fjællingsdal, Kristoffer S; Klöckner, Christian A

    2017-01-01

    Based on a thorough review of psychological literature, this article seeks to develop a model of game enjoyment and environmental learning (ENvironmental EDucational Game Enjoyment Model, ENED-GEM) and delineate psychological processes that might facilitate learning and inspire behavioral change from educational games about the environment. A critically acclaimed digital educational game about environmental issues (Fate of the World by Red Redemption/Soothsayer Games) was used as a case study. Two hundred forty-nine reviews of the game from the popular gaming and reviewing platform known as Steam were analyzed by means of a thematic content analysis in order to identify key player enjoyment factors believed to be relevant to the process of learning from games, as well as to gain an understanding of positive and negative impressions about the game's general content. The end results of the thematic analysis were measured up to the suggested ENED-GEM framework. Initial results generally support the main elements of the ENED-GEM, and future research into the importance of these individual core factors is outlined.

  4. Spray-deposition and photopolymerization of organic-inorganic thiol-ene resins for fabrication of superamphiphobic surfaces.

    Xiong, Li; Kendrick, Laken L; Heusser, Hannele; Webb, Jamie C; Sparks, Bradley J; Goetz, James T; Guo, Wei; Stafford, Christopher M; Blanton, Michael D; Nazarenko, Sergei; Patton, Derek L

    2014-07-09

    Superamphiphobic surfaces, exhibiting high contact angles and low contact angle hysteresis to both water and low surface tension liquids, have attracted a great deal attention in recent years because of the potential of these materials in practical applications such as liquid-resistant textiles, self-cleaning surfaces, and antifouling/anticorrosion coatings. In this work, we present a simple strategy for fabricating of superamphiphobic coatings based on photopolymerization of hybrid thiol-ene resins. Spray-deposition and UV photopolymerization of thiol-ene resins containing hydrophobic silica nanoparticles and perfluorinated thiols provide a multiscale topography and low-energy surface that endows the surface with superamphiphobicity. The wettability and chemical composition of the surfaces were characterized by contact-angle goniometry and X-ray photoelectron spectroscopy, respectively. The hierarchical roughness features of the thiol-ene surfaces were investigated with field-emission scanning electron microscopy. Droplet impact and sandpaper abrasion tests indicate the coatings respectively possess a robust antiwetting behavior and good mechanical durability.

  5. Iron complexes of tetramine ligands catalyse allylic hydroxyamination via a nitroso–ene mechanism

    David Porter

    2015-12-01

    Full Text Available Iron(II complexes of the tetradentate amines tris(2-pyridylmethylamine (TPA and N,N′-bis(2-pyridylmethyl-N,N′-dimethylethane-1,2-diamine (BPMEN are established catalysts of C–O bond formation, oxidising hydrocarbon substrates via hydroxylation, epoxidation and dihydroxylation pathways. Herein we report the capacity of these catalysts to promote C–N bond formation, via allylic amination of alkenes. The combination of N-Boc-hydroxylamine with either FeTPA (1 mol % or FeBPMEN (10 mol % converts cyclohexene to the allylic hydroxylamine (tert-butyl cyclohex-2-en-1-yl(hydroxycarbamate in moderate yields. Spectroscopic studies and trapping experiments suggest the reaction proceeds via a nitroso–ene mechanism, with involvement of a free N-Boc-nitroso intermediate. Asymmetric induction is not observed using the chiral tetramine ligand (+-(2R,2′R-1,1′-bis(2-pyridylmethyl-2,2′-bipyrrolidine ((R,R′-PDP.

  6. Inspection and monitoring plan, contaminated groundwater seeps 317/319/ENE Area, Argonne National Laboratory

    1996-01-01

    During the course of completing the Resource Conservation and Recovery Act (RCRA) Facility Investigation (RFI) in the 317/319/East-Northeast (ENE) Area of Argonne National Laboratory-East (ANL-E), groundwater was discovered moving to the surface through a series of groundwater seeps. The seeps are located in a ravine approximately 600 ft south of the ANL-E fence line in Waterfall Glen Forest Preserve. Samples of the seep water were collected and analyzed for selected parameters. Two of the five seeps sampled were found to contain detectable levels of organic contaminants. Three chemical species were identified: chloroform (14--25 microg/L), carbon tetrachloride (56--340 microg/L), and tetrachloroethylene (3--6 microg/L). The other seeps did not contain detectable levels of volatile organics. The nature of the contaminants in the seeps will also be monitored on a regular basis. Samples of surface water flowing through the bottom of the ravine and groundwater emanating from the seeps will be collected and analyzed for chemical and radioactive constituents. The results of the routine sampling will be compared with the concentrations used in the risk assessment. If the concentrations exceed those used in the risk assessment, the risk calculations will be revised by using the higher numbers. This revised analysis will determine if additional actions are warranted

  7. Photolithographic fabrication of solid–liquid core waveguides by thiol-ene chemistry

    Sagar, Kaushal; Gopalakrishnan, Nimi; Christiansen, Mads Brøkner; Kristensen, Anders; Ndoni, Sokol

    2011-01-01

    In this work we demonstrate an efficient and cleanroom compatible method for the fabrication of solid–liquid core waveguides based on nanoporous polymers. We have used thiol-ene photo-grafting to tune and pattern the hydrophilicity of an originally hydrophobic nanoporous 1, 2-polybutadiene. The generated refractive index contrast between the patterned water-filled volume and the surrounding empty hydrophobic porous polymer allows for light confinement within the water-filled volume—the solid–liquid core. The presented fabrication process is simple and fast. It allows a high degree of flexibility on the type and grade of surface chemistry imparted to the large nanoporous area depending upon the application. The fabrication does not need demanding chemical reaction conditions. Thus, it can be readily used on a standard silicon lithography bench. The propagation loss values reported in this work are comparable with literature values for state-of-the-art liquid-core waveguide devices. The demonstrated waveguide function added to the nanoporous polymer with a very high internal surface area makes the system interesting for many applications in different areas, such as diagnostics and bio-chemical sensing

  8. Superhydrophobic and Slippery Lubricant-Infused Flexible Transparent Nanocellulose Films by Photoinduced Thiol-Ene Functionalization.

    Guo, Jiaqi; Fang, Wenwen; Welle, Alexander; Feng, Wenqian; Filpponen, Ilari; Rojas, Orlando J; Levkin, Pavel A

    2016-12-14

    Films comprising nanofibrillated cellulose (NFC) are suitable substrates for flexible devices in analytical, sensor, diagnostic, and display technologies. However, some major challenges in such developments include their high moisture sensitivity and the complexity of current methods available for functionalization and patterning. In this work, we present a facile process for tailoring the surface wettability and functionality of NFC films by a fast and versatile approach. First, the NFC films were coated with a layer of reactive nanoporous silicone nanofilament by polycondensation of trichlorovinylsilane (TCVS). The TCVS afforded reactive vinyl groups, thereby enabling simple UV-induced functionalization of NFC films with various thiol-containing molecules via the photo "click" thiol-ene reaction. Modification with perfluoroalkyl thiols resulted in robust superhydrophobic surfaces, which could then be further transformed into transparent slippery lubricant-infused NFC films that displayed repellency against both aqueous and organic liquids with surface tensions as low as 18 mN·m -1 . Finally, transparent and flexible NFC films incorporated hydrophilic micropatterns by modification with OH, NH 2 , or COOH surface groups, enabling space-resolved superhydrophobic-hydrophilic domains. Flexibility, transparency, patternability, and perfect superhydrophobicity of the produced nanocellulose substrates warrants their application in biosensing, display protection, and biomedical and diagnostics devices.

  9. Polysiloxane-based luminescent elastomers prepared by thiol-ene "click" chemistry.

    Zuo, Yujing; Lu, Haifeng; Xue, Lei; Wang, Xianming; Wu, Lianfeng; Feng, Shengyu

    2014-09-26

    Side-chain vinyl poly(dimethylsiloxane) has been modified with mercaptopropionic acid, methyl 3-mercaptopropionate, and mercaptosuccinic acid. Coordinative bonding of Eu(III) to the functionalized polysiloxanes was then carried out and crosslinked silicone elastomers were prepared by thiol-ene curing reactions of these composites. All these europium complexes could be cast to form transparent, uniform, thin elastomers with good flexibility and thermal stability. The networks were characterized by FTIR, NMR, UV/Vis, and luminescence spectroscopy as well as by scanning electron microscopy, thermogravimetric analysis, and X-ray photoelectron spectroscopy. The europium elastomer luminophores exhibited intense red light at 617 nm under UV excitation at room temperature due to the (5)D0 →(7)F2 transition in Eu(III) ions. The newly synthesized luminescent materials offer many advantages, including the desired mechanical flexibility. They cannot be dissolved or fused, and so they have potential for use in optical and electronic applications. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. Chalcogenidobis(ene-1,2-dithiolate)molybdenum(IV) complexes (chalcogenide E = O, S, Se): probing Mo≡E and ene-1,2-dithiolate substituent effects on geometric and electronic structure.

    Sugimoto, Hideki; Tano, Hiroyuki; Suyama, Koichiro; Kobayashi, Tomoya; Miyake, Hiroyuki; Itoh, Shinobu; Mtei, Regina P; Kirk, Martin L

    2011-02-07

    New square-pyramidal bis(ene-1,2-dithiolate)MoSe complexes, [Mo(IV)Se(L)(2)](2-), have been synthesised along with their terminal sulfido analogues, [Mo(IV)S(L)(2)](2-), using alkyl (L(C(4)H(8))), phenyl (L(Ph)) and methyl carboxylate (L(COOMe)) substituted dithiolene ligands (L). These complexes now complete three sets of Mo(IV)O, Mo(IV)S and Mo(IV)Se species that are coordinated with identical ene-1,2-dithiolate ligands. The [alkyl substituted Mo(S/Se)(L(C(4)H(8)))(2)](2-) complexes were reported in prior investigations (H. Sugimoto, T. Sakurai, H. Miyake, K. Tanaka and H. Tsukube, Inorg. Chem. 2005, 44, 6927, H. Tano, R. Tajima, H. Miyake, S. Itoh and H. Sugimoto, Inorg. Chem. 2008, 47, 7465). The new series of complexes enable a systematic investigation of terminal chalcogenido and supporting ene-1,2-dithiolate ligand effects on geometric structure, electronic structure, and spectroscopic properties. X-ray crystallographic analysis of these (Et(4)N)(2)[MoEL(2)] (E = terminal chalocogenide) complexes reveals an isostructural Mo centre that adopts a distorted square pyramidal geometry. The M≡E bond distances observed in the crystal structures and the ν(M≡E) vibrational frequencies indicate that these bonds are weakened with an increase in L→Mo electron donation (L(COOMe) < L(Ph) < L(C(4)H(8))), and this order is confirmed by an electrochemical study of the complexes. The (77)Se NMR resonances in MoSeL complexes appear at lower magnetic fields as the selenido ion became less basic from MoSeL(C(4)H(8)), MoSeL(Ph) and MoSeL(COOMe). Electronic absorption and resonance Raman spectroscopies have been used to assign key ligand-field, MLCT, LMCT and intraligand CT bands in complexes that possess the L(COOMe) ligand. The presence of low-energy intraligand CT transition in these MoEL(COOMe) compounds directly probes the electron withdrawing nature of the -COOMe substituents, and this underscores the complex electronic structure of square pyramidal bis(ene-1

  11. Synthesis and Transformations of di-endo-3-Aminobicyclo-[2.2.2]oct-5-ene-2-carboxylic Acid Derivatives

    Márta Palkó

    2011-09-01

    Full Text Available all-endo-3-amino-5-hydroxybicyclo[2.2.2]octane-2-carboxylic acid (13 and all-endo-5-amino-6-(hydroxymethylbicyclo[2.2.2]octan-2-ol (10 were prepared via dihydro-1,3-oxazine or g-lactone intermediates by the stereoselective functionalization of an N-protected derivative of endo-3-aminobicyclo[2.2.2]oct-5-ene-2-carboxylic acid (2. Ring closure of b-amino ester 4 resulted in tricyclic pyrimidinones 15 and 16. The structures, stereochemistry and relative configurations of the synthesized compounds were determined by IR and NMR.

  12. Vabariigi presidendi, riigikogu esimehe ja peaministri ühisavaldus 8. mail 2007 / Toomas Hendrik Ilves, Ene Ergma, Andrus Ansip

    Ilves, Toomas Hendrik, 1953-

    2007-01-01

    President Toomas Hendrik Ilvese, Riigikogu spiikri Ene Ergma ja peaminister Andrus Ansipi avaldus Teise maailmasõja lõpu 62. aastapäeva puhul. Ilmunud ka: Severnoje Poberežje 9. mai 2007, lk. 2; Eesti Elu 11. mai 2007, lk. 2, pealk.: Riigijuhtide ühisavaldus Teise maailmasõja mälestuspäeval, ingl. k. lk. 11, pealk.: Joint statement May 8, 2007; ingl. k. Vaba Eesti Sõna 10. mai 2007, lk. 12, pealk.: Joint statement of the President, Speaker of the Parliament and Prime Minister of the Republic of Estonia

  13. Selective fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene by nucleotides.

    Marquez, Cesar; Pischel, Uwe; Nau, Werner M

    2003-10-16

    [reaction: see text] The fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) by nucleotides has been studied. The quenching mechanism was analyzed on the basis of deuterium isotope effects, tendencies for exciplex formation, and the quenching efficiency in the presence of a molecular container (cucurbit[7]uril). Exciplex-induced quenching appears to prevail for adenosine, cytidine, and uridine, while hydrogen abstraction becomes competitive for thymidine and guanosine. Compared to other fluorescent probes, DBO responds very selectively to the type of nucleotide.

  14. Stereoselectivity in ene reactions with 1O2: matrix effects in polymer supports, photo-oxygenation of organic salts and asymmetric synthesis.

    Griesbeck, Axel G; Bartoschek, Anna; Neudörfl, Jörg; Miara, Claus

    2006-01-01

    The ene reaction of chiral allylic alcohols is applied as a tool for the investigation of intrapolymer effects by means of the stereoselectivity of the singlet-oxygen addition. The diastereo selectivity strongly depends on the structure of the polymer, the substrate loading degree and also on the degree of conversion demonstrating additional supramolecular effects evolving during the reaction. The efficiency and the stability of polymer-bound sensitizers were evaluated by the ene reaction of singlet oxygen with citronellol. The ene reaction with chiral ammonium salts of tiglic acid was conducted under solution phase conditions or in polystyrene beads under chiral contact ion-pair conditions. The products thus obtained precipitate during the photoreaction as ammonium salts. Moderate asymmetric induction was observed for this procedure for the first time.

  15. Evaluation of fracture toughness and mechanical properties of ternary thiol-ene-methacrylate systems as resin matrix for dental restorative composites.

    Beigi, Saeed; Yeganeh, Hamid; Atai, Mohammad

    2013-07-01

    Study and evaluation of fracture toughness, flexural and dynamic mechanical properties, and crosslink density of ternary thiol-ene-methacrylate systems and comparison with corresponding conventional methacrylate system were considered in the present study. Urethane tetra allyl ether monomer (UTAE) was synthesized as ene monomer. Different formulations were prepared based on combination of UTAE, BisGMA/TEGDMA and a tetrathiol monomer (PETMP). The photocuring reaction was conducted under visible light using BD/CQ combination as photoinitiator system. Mechanical properties were evaluated via measuring flexural strength, flexural modulus and fracture toughness. Scanning electron microscopy (SEM) was utilized to study the morphology of the fractured specimen's cross section. Viscoelastic properties of the samples were also determined by dynamic mechanical thermal analysis (DMTA). The same study was performed on a conventional methacrylate system. The data were analyzed and compared by ANOVA and Tukey HSD tests (significance level=0.05). The results showed improvement in fracture toughness of the specimens containing thiol-ene moieties. DMTA revealed a lower glass transition temperature and more homogenous structure for thiol-ene containing specimens in comparison to the system containing merely methacrylate monomer. The flexural modulus and flexural strength of the specimens with higher thiol-ene content were lower than the neat methacrylate system. The SEM micrographs of the fractured surface of specimens with higher methacrylate content were smooth and mirror-like (shiny) which represent brittle fracture. The thiol-ene-methacrylate system can be used as resin matrix of dental composites with enhanced fracture toughness in comparison to the methacrylate analogous. Copyright © 2013 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  16. Thiol-ene and photo-cleavage chemistry for controlled presentation of biomolecules in hydrogels.

    Grim, Joseph C; Marozas, Ian A; Anseth, Kristi S

    2015-12-10

    photochemical methods have led to important advances in the tissue regeneration community, namely the thiol-ene photo-click reaction for bioconjugation and photocleavage reactions that allow for the removal of protecting groups. Specific examples will be highlighted where these methodologies have been used to engineer hydrogels that control and direct cell function with the aim of inspiring their use in regenerative medicine. Copyright © 2015 Elsevier B.V. All rights reserved.

  17. Stavovi medicinskih sestara u Hrvatskoj o primarnom oživljavanju prijevremeno rođene novorođenčadi

    Bilić, Iva; Prpić, Igor; Radić, Jelena; Vukelić, Petar; Petrović, Ana; Juretić, Emilija; Furlan, Ivanka

    2008-01-01

    CILJ: Cilj istraživanja bilo je ispitati stavove medicinskih sestara u Hrvatskoj o primarnom oživljavanju prijevremeno rođene djece. METODE: Pisanom anketom ispitivana je dob, roditeljstvo, radno iskustvo i mjesto rada te stavovi medicinskih sestara iz Hrvatske o primarnom oživljavanju prijevremeno rođene djece. Anketirano je 174 medicinskih sestara; 49 zaposlenih u rađaonici ili na mjestima rada sa trudnicama (Rađ/Tr), 79 u pedijatrijskim/ neonatološkim jedinicama intenzivnog liječenja (...

  18. Investigation of curing rates of bio-based thiol-ene films from diallyl 2,5-furandicaboxylate

    Larsen, Daniel Bo; Sønderbæk-Jørgensen, Rene; Duus, Jens Ø.

    2018-01-01

    The bio-based monomer, 2,5-furandicarboxylic acid, has been adapted to classic thiol-ene chemistry by derivatization of the acid with allyl alcohol. This new monomer has allowed for the synthesis of new thermoset systems, capable of forming green, sustainable materials through UV-crosslinking. In......The bio-based monomer, 2,5-furandicarboxylic acid, has been adapted to classic thiol-ene chemistry by derivatization of the acid with allyl alcohol. This new monomer has allowed for the synthesis of new thermoset systems, capable of forming green, sustainable materials through UV......-crosslinking. In this study, the synthesis of the new monomer along with thorough kinetic studies of the new thermoset systems are presented. In order to determine kinetic values for the systems, all reactions have been followed by real-time FT-IR. Initially, a study of three different photoinitiators is performed...... on a classic TEMPIC-TATATO system, in order to determine the superior initiator for the new systems. The new monomer is crosslinked with five different thiol compounds in both stoichiometric and off-stoichiometric ratios, yielding an array of bio-based thermosets. The properties of these systems are determined...

  19. Thiol-ene click chemistry derived cationic cyclodextrin chiral stationary phase and its enhanced separation performance in liquid chromatography.

    Yao, Xiaobin; Tan, Timothy Thatt Yang; Wang, Yong

    2014-01-24

    This work is the first demonstration of a simple thiol-ene click chemistry to anchor vinyl imidazolium β-CD onto thiol silica to form a novel cationic native cyclodextrin (CD) chiral stationary phase (CSP). The CSP afforded high enantioseparation ability towards dansyl (Dns) amino acids, carboxylic aryl compounds and flavonoids in chiral HPLC. The current CSP demonstrates the highest resolving ability (selectivity >1.1, resolution >1.5) towards Dns amino acids in a mobile phase buffered at pH=6.5, with the resolution of Dns-dl-leucine as high as 6.97. 2,4-dichloride propionic acid (2,4-ClPOPA) was well resolved with the selectivity and resolution of 1.37 and 4.88, respectively. Compared to a previously reported native CD-CSP based on a triazole linkage, the current cationic CD-CSP shows a stronger retention and higher resolution towards acidic chiral compounds, ascribed to the propitious strong electrostatic attraction. Stability evaluation results indicated that thiol-ene reaction can provide a facile and robust approach for the preparation of positively charged CD CSPs. Copyright © 2013 Elsevier B.V. All rights reserved.

  20. Functional characterization and stability improvement of a ‘thermophilic-like’ ene-reductase from Rhodococcus opacus 1CP

    Anika eRiedel

    2015-10-01

    Full Text Available Ene-reductases are widely applied for the asymmetric synthesis of relevant industrial chemicals. A novel ene-reductase OYERo2 was found within a set of 14 putative Old Yellow Enzymes (OYEs obtained by genome mining of the actinobacterium Rhodococcus opacus 1CP. Multiple sequence alignment suggested that the enzyme belongs to the group of ‘thermophilic-like’ OYEs. OYERo2 was produced in Escherichia coli and biochemically characterized. The enzyme is strongly NADPH dependent and uses non-covalently bound FMNH2 for the reduction of activated α,β-unsaturated alkenes. In the active form OYERo2 is a dimer. Optimal catalysis occurs at pH 7.3 and 37 °C. OYERo2 showed highest specific activities (4550 U mg-1 on maleimides, which are efficiently converted to the corresponding succinimides. The OYERo2-mediated reduction of prochiral alkenes afforded the (R-products with excellent optical purity (ee > 99%. OYERo2 is not as thermo-resistant as related OYEs. Introduction of a characteristic intermolecular salt bridge by site-specific mutagenesis raised the half-life of enzyme inactivation at 32 °C from 28 min to 87 min and improved the tolerance towards organic co-solvents. The suitability of OYERo2 for application in industrial biocatalysis is discussed.

  1. Biocatalysis with thermostable enzymes: structure and properties of a thermophilic 'ene'-reductase related to old yellow enzyme.

    Adalbjörnsson, Björn V; Toogood, Helen S; Fryszkowska, Anna; Pudney, Christopher R; Jowitt, Thomas A; Leys, David; Scrutton, Nigel S

    2010-01-25

    We report the crystal structure of a thermophilic "ene" reductase (TOYE) isolated from Thermoanaerobacter pseudethanolicus E39. The crystal structure reveals a tetrameric enzyme and an active site that is relatively large compared to most other structurally determined and related Old Yellow Enzymes. The enzyme adopts higher order oligomeric states (octamers and dodecamers) in solution, as revealed by sedimentation velocity and multiangle laser light scattering. Bead modelling indicates that the solution structure is consistent with the basic tetrameric structure observed in crystallographic studies and electron microscopy. TOYE is stable at high temperatures (T(m)>70 degrees C) and shows increased resistance to denaturation in water-miscible organic solvents compared to the mesophilic Old Yellow Enzyme family member, pentaerythritol tetranitrate reductase. TOYE has typical ene-reductase properties of the Old Yellow Enzyme family. There is currently major interest in using Old Yellow Enzyme family members in the preparative biocatalysis of a number of activated alkenes. The increased stability of TOYE in organic solvents is advantageous for biotransformations in which water-miscible organic solvents and biphasic reaction conditions are required to both deliver novel substrates and minimize product racemisation.

  2. (E-2-((4R,5R-5-((Benzyloxymethyl-2,2-dimethyl-1,3-dioxolan-4-ylbut-2-ene-1,4-diol

    Carlos R. Carreras

    2010-04-01

    Full Text Available The synthesis of (E-2-((4R,5R-5-((benzyloxymethyl-2,2-dimethyl-1,3-dioxolan-4-ylbut-2-ene-1,4-diol by a one-step reduction of the appropriate 2-substituted butenolide is reported. Product characterization was carried out by IR, 1H NMR, 13C NMR, MS, elemental analysis and optical rotation.

  3. Kui oluliseks isikuandmete kaitsmist kooli oludes peate ja millest seda tehes lähtute? / Harri Kõo, Ene Tannberg, Kalle Niinas, Maria Tiro...[jt.

    2008-01-01

    Küsimusele vastavad Tabasalu Ühisgümnaasiumi direktor Harri Kõo, Tartu Miina Härma Gümnaasiumi direktor Ene Tannberg, Jakob Westholmi Gümnaasiumi direktor Kalle Niinas, Jüri Gümnaasiumi direktor Maria Tiro ja Viimsi Keskkooli direktor Leelo Tiisvelt

  4. Katkenud õpingute teise kõrgkooli "kolimine" nõuab visadust / Agne Narusk, Ene Küüner, Heli Mattisen, Kadri Osula

    Narusk, Agne

    2007-01-01

    Pooleli jäänud ülikooliõpingute lõpetamisest. Varasemate õpingute ja töökogemuse arvestamise tingimusi õpingute jätkamisel selgitavad Tartu Ülikooli avatud ülikooli tasemeõppe koordinaator Ene Küüner, Tallinna Ülikooli akadeemiline prorektor Heli Mattisen ja Estonian Business Schoolì õppeosakonna juhataja Kadri Osula

  5. Ene-Liis Semper: selle aasta puhkepäevad võib ühe käe sõrmedel kokku lugeda

    Semper, Ene-Liis, 1969-

    2011-01-01

    Tallinna kultuuripealinna projekti panustanud Ene-Liis Semper võtab 2011. aasta sündmused kokku ja selgitab, kuidas jõudsid publiku ette suurlavastused "The Rise and Fall of Estonia", "Three Kingdoms", Põhuteater ning isikunäitus Kumus

  6. Joint statement of the President, Speaker of the Riigikogu and Prime Minister of the Republic of Estonia / Toomas Hendrik Ilves, Ene Ergma, Andrus Ansip

    Ilves, Toomas Hendrik, 1953-

    2008-01-01

    President Toomas Hendrik Ilvese, Riigikogu spiikri Ene Ergma ja peaminister Andrus Ansipi ühisavaldus Teise maailmasõja lõpu 62. aastapäeva puhul 8. mail 2007, milles kinnitatakse, et hoolimata Teise maailmasõja ajaloolistest tõlgendustest on kõik Eestis elavad inimesed vabad ning jagavad ühist tulevikku

  7. One-step fabrication of PEGylated fluorescent nanodiamonds through the thiol-ene click reaction and their potential for biological imaging

    Huang, Hongye; Liu, Meiying; Tuo, Xun; Chen, Junyu; Mao, Liucheng; Wen, Yuanqing; Tian, Jianwen; Zhou, Naigen; Zhang, Xiaoyong; Wei, Yen

    2018-05-01

    Over the past years, fluorescent carbon nanoparticles have got growing interest for biological imaging. Fluorescent nanodiamonds (FNDs) are novel fluorescent carbon nanoparticles with multitudinous useful properties, including remarkable fluorescence properties, extremely low toxicity and high refractive index. However, facile preparation of FNDs with designable properties and functions from non-fluorescent detonation nanodiamonds (DNDs) has demonstrated to be challengeable. In this work, we reported for the first time that preparation of Polyethylene glycol (PEG) functionalized FNDs through a one-step thiol-ene click reaction using thiol containing PEG (PEG-SH) as the coating agent. Based on the characterization results, we demonstrated that PEG-SH could be efficiently introduced on DNDs to obtain FNDs through the thiol-ene click chemistry. The resultant FND-PEG composites showed high water dispersibility, strong fluorescence and low cytotoxicity. Moreover, FND-PEG composites could be internalized by cells and displayed good cell dyeing performance. All of these features implied that FND-PEG composites are of great potential for biological imaging. Taken together, a facile one-step strategy based on the one-step thiol-ene click reaction has been developed for efficient preparation of FND-PEG composites from non-fluorescent DNDs. The strategy should be also useful for fabrication of many other functional FNDs via using different thiol containing compounds for the universality of thiol-ene click reaction.

  8. A neutral polyacrylate copolymer coating for surface modification of thiol-ene microchannels for improved performance of protein separation by microchip electrophoresis

    Mesbah, Kiarach; Mai, T.D.; Jensen, Thomas Glasdam

    2016-01-01

    We have investigated the behavior of thiol-ene substrates that is a class of promising materials for lab-on-a-chip electrophoresis applications. Two polymeric materials were prepared by copolymerization of N, N-dimethylacrylamide (DMA), (3-(methacryloyl-oxy)propyl)trimethoxysilane (PMA) and 3-tri...

  9. Stereochemistry of 16a-Hydroxyfriedelin and 3-Oxo-16-methylfriedel-16-ene Established by 2D NMR Spectroscopy

    Vagner Fernandes Knupp

    2009-02-01

    Full Text Available Friedelin (1, 3b-friedelinol (2, 28-hydroxyfriedelin (3, 16a-hydroxyfriedelin (4, 30-hydroxyfriedelin (5 and 16a,28-dihydroxyfriedelin (6 were isolated through fractionation of the hexane extract obtained from branches of Salacia elliptica. After a week in CDCl3 solution, 16a-hydroxyfriedelin (4 reacted turning into 3-oxo-16-methylfriedel-16-ene (7. This is the first report of a dehydration followed by a Nametkin rearrangement of a pentacyclic triterpene in CDCl3 solution occurring in the NMR tube. These seven pentacyclic triterpenes was identified through NMR spectroscopy and the stereochemistry of compound 4 and 7 was established by 2D NMR (NOESY spectroscopy and mass spectrometry (GC-MS. It is also the first time that all the 13C-NMR and 2D NMR spectral data are reported for compounds 4 and 7.

  10. Modifying surface resistivity and liquid moisture management property of keratin fibers through thiol-ene click reactions.

    Yu, Dan; Cai, Jackie Y; Church, Jeffrey S; Wang, Lijing

    2014-01-22

    This paper reports on a new method for improving the antistatic and liquid moisture management properties of keratinous materials. The method involves the generation of thiols by controlled reduction of cystine disulfide bonds in keratin with tris(2-carboxyethyl) phosphine hydrochloride and subsequent grafting of hydrophilic groups onto the reduced keratin by reaction with an acrylate sulfonate or acrylamide sulfonate through thiol-ene click chemistry. The modified substrates were characterized with Raman spectroscopy and scanning electron microscopy and evaluated for their performance changes in liquid moisture management, surface resistivity, and wet burst strength. The results have revealed that the thiol-acrylate reaction is more efficient than the thiol-acrylamide reaction, and the keratinous substrate modified with an acrylate sulfonate salt exhibits significantly improved antistatic and liquid moisture management properties.

  11. Facile preparation of organic-silica hybrid monolith for capillary hydrophilic liquid chromatography based on "thiol-ene" click chemistry.

    Chen, Ming-Luan; Zhang, Jun; Zhang, Zheng; Yuan, Bi-Feng; Yu, Qiong-Wei; Feng, Yu-Qi

    2013-04-05

    In this work, a one-step approach to facile preparation of organic-inorganic hybrid monoliths was successfully developed. After vinyl-end organic monomers and azobisisobutyronitrile (AIBN) were mixed with hydrolyzed tetramethoxysilane (TMOS) and 3-mercaptopropyltrimethoxysilane (MPTMS), the homogeneous mixture was introduced into a fused-silica capillary for simultaneous polycondensation and "thiol-ene" click reaction to form the organic-silica hybrid monoliths. By employing this strategy, two types of organic-silica hybrid monoliths with positively charged quaternary ammonium and amide groups were prepared, respectively. The functional groups were successfully introduced onto the monoliths during the sol-gel process with "thiol-ene" click reaction, which was demonstrated by ζ-potential assessment, energy dispersive X-ray spectroscopy (EDX), and Fourier transform infrared (FT-IR) spectroscopy. The porous structure of the prepared monolithic columns was examined by scanning electron microscopy (SEM), nitrogen adsorption-desorption measurement, and mercury intrusion porosimetry. These results indicate the prepared organic-silica hybrid monoliths possess homogeneous column bed, large specific surface area, good mechanical stability, and excellent permeability. The prepared monolithic columns were then applied for anion-exchange/hydrophilic interaction liquid chromatography. Different types of analytes, including benzoic acids, inorganic ions, nucleosides, and nucleotides, were well separated with high column efficiency around 80,000-130,000 plates/m. Taken together, we present a facile and universal strategy to prepare organic-silica hybrid monoliths with a variety of organic monomers using one-step approach. Copyright © 2013 Elsevier B.V. All rights reserved.

  12. Kingipaanika, ai, ai, ai! / Mari Rebane

    Rebane, Mari

    2003-01-01

    Jõulukingituseks sobilike raamatute ja heliplaatide tutvustus. Heliplaadid: Urmas Alender "Kohtumine Albertiga", Tõnu Tepandi "Kõlakoda", Pet Shop Boys "Pop Art", Erasure "Very Best Of", Depeche Mode "101", Kylie Minogue "Body Language", Korn "Take a Look in the Mirror", "Once Upon a time in Mexico"

  13. Bon appetite! / Mari-Liis Rebane

    Rebane, Mari-Liis

    2009-01-01

    Pimedate Ööde 13. filmifestivali alafestivali Animated Dreams täispikki animafilme: Austraalia "Mary ja Max" (režissöör Elliot, Adam), Rootsi-Taani-Norra "Metropia" (režissöör Tarik Saleh), Iisraeli-Austraalia "9,99 dollarit" (režissöör Tatia Rosenthal)

  14. Neokontshennaja voina Alfonsa Rebane / Ilja Nikiforov

    Nikiforov, Ilja

    1999-01-01

    Vt. ka Narvskaja Gazeta 1. juuli, lk. 4. Saksa sõjaväe Eesti Julgestusgrupi 181 ülema, esimese eestlasest Rüütliristi kavaleri kolonel Alfons Rebase (1908-1976) põrm toodi kodumaale ja maeti 26. juunil Metsakalmistule

  15. Tihii omut / Peeter Rebane ; interv. Aleksandra Manukjan

    Rebane, Peeter, 1973-

    2004-01-01

    Uuest kohvikust ja gei-klubist "Angel" Tallinnas. Stiilse atmosfääri loomisel olid abiks stilist Gerly Tinn, graafikadisainer Rain Pikand ja reklaamifirma Division. Sisekujunduse tegi disainer John Gregg Suurbritanniast

  16. Soodusrenoveerimine kogub hoogu / Selene-Rete Rebane

    Rebane, Selene-Rete

    2002-01-01

    Tallinna kultuuriväärtuste ameti poolt koos erafirmadega käivitatud projekti "Vana maja korda" raames restaureeritakse puitmajde uksi ning väljastatkse värvipasse, mille alusel saab soodushinnaga fassaadivärve osta

  17. Puitpitsvilla meenutab kunagisi hiilgeaegu / Mari Rebane

    Rebane, Mari

    2004-01-01

    2003. a. Tartus väljaantud arhitektuuriraamat "Puitpitsvilla" eksponeerib Narva-Jõesuu puitvillasid. Pildid on Tartu Kõrgema Kunstikooli lõpetanud fotograafidelt Liisi Siibakult ja Aili Paadilt, saatesõna Tartu Ülikooli doktorandilt arhitektuuriajaloolaselt Epi Tohvrilt

  18. Eesti kirjandusse saabusid esimesed "blaamatud" / Mari Rebane

    Rebane, Mari

    2007-01-01

    Petrone, Epp. Minu Ameerika : reportaaže ja pihtimusi 2003-2006. 1. osa. Tartu : Petrone Print, 2007 ; Petrone, Epp ; Reintam, Dagmar. Õun ära süüa? : [SL Õhtulehe populaarne suvejutt koos epiloogidega ja lisadega. Tallinn] : Pegasus, 2007 ; Reintam, Dagmar. daki.elab.siin. Tartu : Petrone Print, 2007

  19. Õnnelik Cecilia / Peeter Rebane

    Rebane, Peeter, 1973-

    2005-01-01

    Pärnu 19. dokumentaal- ja antropoloogiafilmide festivalil nähtavatest dokumentaalfilmidest jõuab teleekraanile seitse filmi armastusest ja abielust. Filme arvustavad Eesti kultuuri- ja ühiskonnategelased. Dokumentaalfilm "Isainstinkt", režissöör Murray Nossel

  20. Turismikampaania hillitses oma reklaamiklippe / Mari Rebane

    Rebane, Mari

    2005-01-01

    Turismikampaaniaks valmistatud videoklippi muudeti Eestist saadud negatiivse tagasiside tõttu. Turismikampaania teostaja OÜ Brilliant Marketing Communication partner Aivar Laan selgitab videoklippide eemaldamist kampaania kodulehelt

  1. Sajandi õudseimad horror-filmid / Mari Rebane

    Rebane, Mari

    2004-01-01

    Meelelahutusajakirja "Entertainment Weekly" valis läheneva halloweeni puhuks välja parimad ja õudsemad õudusfilmid. Kõrgeima kunstilise tasemega õudusfilmiks tunnistati Stanley Kubricku "The Shining" (1980)

  2. The IS-ENES climate4impact portal: bridging the CMIP5 and CORDEX data to impact users

    Som de Cerff, Wim; Plieger, Maarten; Page, Christian; Tatarinova, Natalia; Hutjes, Ronald; de Jong, Fokke; Bärring, Lars; Sjökvist, Elin; Vega Saldarriaga, Manuel; Santiago Cofiño Gonzalez, Antonio

    2015-04-01

    The aim of climate4impact (climate4impact.eu) is to enhance the use of Climate Research Data and to enhance the interaction with climate effect/impact communities. The portal is based on 17 impact use cases from 5 different European countries, and is evaluated by a user panel consisting of use case owners. It has been developed within the IS-ENES European project and is currently operated and further developed in the IS ENES2 project. As the climate impact community is very broad, the focus is mainly on the scientific impact community. Climate4impact is connected to the Earth System Grid Federation (ESGF) nodes containing global climate model data (GCM data) from the fifth phase of the Coupled Model Intercomparison Project (CMIP5) and regional climate model data (RCM) data from the Coordinated Regional Climate Downscaling Experiment (CORDEX). This global network of climate model data centers offers services for data description, discovery and download. The climate4impact portal connects to these services using OpenID, and offers a user interface for searching, visualizing and downloading global climate model data and more. A challenging task is to describe the available model data and how it can be used. The portal informs users about possible caveats when using climate model data. All impact use cases are described in the documentation section, using highlighted keywords pointing to detailed information in the glossary. Climate4impact currently has two main objectives. The first one is to work on a web interface which automatically generates a graphical user interface on WPS endpoints. The WPS calculates climate indices and subset data using OpenClimateGIS/icclim on data stored in ESGF data nodes. Data is then transmitted from ESGF nodes over secured OpenDAP and becomes available in a new, per user, secured OpenDAP server. The results can then be visualized again using ADAGUC WMS. Dedicated wizards for processing of climate indices will be developed in close

  3. Thiol-ene thermosets exploiting surface reactivity for layer-by-layer structures and control of penetration depth for selective surface reactivity

    Daugaard, Anders Egede; Westh, Andreas; Pereira Rosinha Grundtvig, Ines

    Thiol-ene thermosets have been shown to be an efficient platform for preparation of functional polymer surfaces. Especially the effectiveness and versatility of the system has enabled a large variety of network properties to be obtained in a simple and straight-forward way. Due to its selectivity......, various thiols and allyl or other vinyl reactants can be used to obtain either soft and flexible1 or more rigid functional thermosets 2. The methodology permits use of etiher thermal or photochemical conditions both for matrix preparation as well as for surface functionalization. Due to excess reactive...... groups in thµe surface of thiol-ene thermosets, it is possible to prepare surface functional thermosets or to exploit the reactive groups for modular construction and subsequent chemical bonding. Here a different approach preparing monolithic layer-by-layer structures with controlled mechanical...

  4. Facile synthesis of linear-dendritic cholesteryl-poly(epsilon-caprolactone)-b-(L-lysine)(G2) by thiol-ene and azide-alkyne "click" reactions

    Javakhishvili, Irakli; Binder, W.H.; Tanner, S.

    2010-01-01

    The construction of a linear-dendritic block copolymer consisting of terminal cholesteryl moiety, poly(epsilon-caprolactone), and a second generation L-lysine dendron has been accomplished by the combination of copper(I) catalyzed azide-alkyne and UV-triggered thiol-ene "click" reactions. Ring-op...... and thiocholesterol. Near to quantitative functionalization of the intermediate and final products has been attained as confirmed by NMR spectroscopy and MALDI-TOF spectrometry....

  5. Cyclohex-1-ene carboxylic acids: synthesis and biological evaluation of novel inhibitors of human 5 alpha reductase.

    Baston, Eckhard; Salem, Ola I A; Hartmann, Rolf W

    2003-03-01

    In search of novel nonsteroidal mimics of steroidal inhibitors of 5 alpha reductase, 4-(2-phenylethyl)cyclohex-1-ene carboxylic acids 1-5 were synthesized with different substituents in para position of the phenyl ring (1: N, N-diisopropylcarbamoyl, 2: phenyl, 3: phenoxy, 4: benzoyl, and 5: benzyl). The principal synthetic approach for the desired compounds consisted of a Wittig olefination between 1, 4-dioxaspiro [4.5]-decane-8-carbaldehyde (4g and the appropriate phosphonium salts. The compounds were tested for inhibition of human 5 alpha reductase isozymes 1 and 2 using DU 145 cells and preparations from prostatic tissue, respectively. They turned out to be good inhibitors of the prostatic isozyme 2 with compound 1 being the most potent one (IC(50) = 760 nM). Isozyme 1 was only slightly inhibited. It is concluded that the novel structures are appropriate for being further optimized, aiming at the development of a novel drug for the treatment of benign prostatic hyperplasia.

  6. Olean-18-ene triterpenoids from Celastraceae species inhibit HIV replication targeting NF-kB and Sp1 dependent transcription.

    Osorio, Alex A; Muñóz, Alejandro; Torres-Romero, David; Bedoya, Luis M; Perestelo, Nayra R; Jiménez, Ignacio A; Alcamí, José; Bazzocchi, Isabel L

    2012-06-01

    In the present study we report the isolation of nine new olean-18-ene triterpenes (1-9), along with three known ones (10-12), from Cassine xylocarpa and Maytenus jelskii. Their stereostructures have been elucidated on the basis of spectroscopic analysis, including 1D and 2D NMR techniques (COSY, ROESY, HSQC and HMBC), and spectrometric methods. The natural compounds and derivatives 13-15 have been tested for their potential as inhibitors of human immunodeficiency virus type 1 replication. Five compounds from this series displayed potent antiviral activity with IC(50)s in the micromolar range (1, 3, 4, 7 and 8) being 1 and 8 the most active compounds. The target of these compounds was different from antiretroviral drugs currently licensed as they act as inhibitors of enhancer-dependent transcription. The structure-activity relationships were established based on the regiosubstitution and oxidation degree of the triterpene scaffold, revealing that these aspects were able to modulate the selectivity and intensity of HIV inhibition. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

  7. Investigations on the fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene by certain flavonoids.

    Anbazhagan, V; Kalaiselvan, A; Jaccob, M; Venuvanalingam, P; Renganathan, R

    2008-05-29

    The fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) by seven flavonoids namely flavone, flavanone, quercetin, rutin, genistein, diadzein and chrysin has been investigated in acetonitrile and dichloromethane solvents. The bimolecular quenching rate constants lie in the range of 0.09-5.75 x 10(9)M(-1)s(-1) and are explained in terms of structure of the flavonoids studied. The reactivity of flavonoids are in the order: quercetin>rutin>genistein>diadzein>chrysin>flavone>flavanone. The quenching rate constants (k(q)) increase with increase in the number of -OH groups. The endergonic thermodynamic values of DeltaG(et) reveal that electron transfer quenching mechanism can be ruled out. Bond dissociation enthalpy calculations reveal that the position of -OH is important. Further in vitro-antioxidant activities of flavonoids were evaluated with rat liver catalase by gel electrophoresis. The deuterium isotope effect thus observed in this work provides evidence for hydrogen abstraction involved in the quenching process of singlet excited DBO by flavonoids. The data suggest the involvement of direct hydrogen atom transfer (radical scavenging) in the fluorescence quenching of DBO. Bond dissociation enthalpy calculation performed at B3LYP/6-31G(p')//B3LYP/3-21G level are in excellent agreement with the above observations and further reveal that the number OH groups and position of them decide the quenching ability of the flavonoids.

  8. Theoretical study on the photolysis mechanism of 2,3-diazabicyclo[2.2.2]oct-2-ene.

    Chen, Hui; Li, Shuhua

    2005-09-28

    A CASPT2/CASSCF study has been carried out to investigate the mechanism of the photolysis of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) under direct and triplet-sensitized irradiation. By exploring the detailed potential energy surfaces including intermediates, transition states, conical intersections, and singlet/triplet crossing points, for the first excited singlet (S(1)) and the low-lying triplet states (T(1), T(2), and T(3)), we provide satisfactory explanations of many experimental findings associated with the photophysical and photochemical processes of DBO. A key finding of this work is the existence of a significantly twisted S(1) minimum, which can satisfactorily explain the envelope of the broad emission band of DBO. It is demonstrated that the S(1) (n-pi*) intermediate can decay to the T(1) (n-pi*) state by undergoing intersystem crossing (rather inefficient) to the T(2) (pi-pi*) state followed by internal conversion to the T(1) state. The high fluorescence yield and the extraordinarily long lifetime of the singlet excited DBO are due to the presence of relatively high barriers, both for intersystem crossing and for C-N cleavage. The short lifetime of the triplet DBO is caused by fast radiationless decay to the ground state.

  9. Thiol-Ene Photo-Click Collagen-PEG Hydrogels: Impact of Water-Soluble Photoinitiators on Cell Viability, Gelation Kinetics and Rheological Properties

    Róisín Holmes

    2017-06-01

    Full Text Available Thiol-ene photo-click hydrogels were prepared via step-growth polymerisation using thiol-functionalised type-I collagen and 8-arm poly(ethylene glycol norbornene-terminated (PEG-NB, as a potential injectable regenerative device. Type-I collagen was thiol-functionalised by a ring opening reaction with 2-iminothiolane (2IT, whereby up to 80 Abs.% functionalisation and 90 RPN% triple helical preservation were recorded via 2,4,6-Trinitrobenzenesulfonic acid (TNBS colorimetric assay and circular dichroism (CD. Type, i.e., either 2-Hydroxy-1-[4-(2-hydroxyethoxy phenyl]-2-methyl-1-propanone (I2959 or lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP, and concentration of photoinitiator were varied to ensure minimal photoinitiator-induced cytotoxicity and to enable thiol-ene network formation of collagen-PEG mixtures. The viability of G292 cells following 24 h culture in photoinitiator-supplemented media was largely affected by the photoinitiator concentration, with I2959-supplemented media observed to induce higher toxic response (0.1 → 0.5% (w/v I2959, cell survival: 62 → 2 Abs.% compared to LAP-supplemented media (cell survival: 86 → 8 Abs.%. In line with the in vitro study, selected photoinitiator concentrations were used to prepare thiol-ene photo-click hydrogels. Gelation kinetics proved to be largely affected by the specific photoinitiator, with LAP-containing thiol-ene mixtures leading to significantly reduced complete gelation time (τ: 187 s with respect to I2959-containing mixtures (τ: 1683 s. Other than the specific photoinitiator, the photoinitiator concentration was key to adjusting the hydrogel storage modulus (G’, whereby 15-fold G’ increase (232 → 3360 Pa was observed in samples prepared with 0.5% (w/v compared to 0.1% (w/v LAP. Further thiol-ene formulations with 0.5% (w/v LAP and varied content of PEG-NB were tested to prepare photo-click hydrogels with porous architecture, as well as tunable storage modulus (G

  10. Regulation of a putative corticosteroid, 17, 21-dihydroxypregn-4-ene, 3, 20-one, in sea lamprey, Petromyzon marinus.

    Roberts, Brent W.; Didier, Wes; Satbir, Rai; Johnson, Nicholas S.; Libants, Scot V.; Sang-Seon, Yun; Close, David

    2013-01-01

    In higher vertebrates, in response to stress, the hypothalamus produces corticotropin-releasing hormone (CRH), which stimulates cells in the anterior pituitary to produce adrenocorticotropic hormone (ACTH), which in turn stimulates production of either cortisol (F) or corticosterone (B) by the adrenal tissues. In lampreys, however, neither of these steroids is present. Instead, it has been proposed that the stress steroid is actually 17,21-dihydroxypregn-4-ene-3,20-dione (11-deoxycortisol; S). However, there have been no studies yet to determine its mechanism of regulation or site of production. Here we demonstrate that (1) intraperitoneal injections of lamprey-CRH increase plasma S in a dose dependent manner, (2) intraperitoneal injections of four lamprey-specific ACTH peptides at 100 lg/kg, did not induce changes in plasma S concentrations in either males or females; (3) two lamprey-specific gonadotropin-releasing hormones (GnRH I and III) and arginine-vasotocin (AVT), all at single doses, stimulated S production as well as, or to an even greater extent than CRH; (4) sea lamprey mesonephric kidneys, in vitro, converted tritiated 17a-hydroxyprogesterone (17a-P) into a steroid that had the same chromatographic properties (on HPLC and TLC) as S; (5) kidney tissues released significantly more immunoassayable S into the incubation medium than gill, liver or gonad tissues. One interpretation of these results is that the corticosteroid production of the sea lamprey, one of the oldest extant vertebrates, is regulated through multiple pathways rather than the classical HPI-axis. However, the responsiveness of this steroid to the GnRH peptides means that a reproductive rather than a stress role for this steroid cannot yet be ruled out.

  11. Design and fabrication of uniquely shaped thiol-ene microfibers using a two-stage hydrodynamic focusing design.

    Boyd, Darryl A; Shields, Adam R; Howell, Peter B; Ligler, Frances S

    2013-08-07

    Microfluidic systems have advantages that are just starting to be realized for materials fabrication. In addition to the more common use for fabrication of particles, hydrodynamic focusing has been used to fabricate continuous polymer fibers. We have previously described such a microfluidics system which has the ability to generate fibers with controlled cross-sectional shapes locked in place by in situ photopolymerization. The previous fiber fabrication studies produced relatively simple round or ribbon shapes, demonstrated the use of a variety of polymers, and described the interaction between sheath-core flow-rate ratios used to control the fiber diameter and the impact on possible shapes. These papers documented the fact that no matter what the intended shape, higher flow-rate ratios produced rounder fibers, even in the absence of interfacial tension between the core and sheath fluids. This work describes how to fabricate the next generation of fibers predesigned to have a much more complex geometry, as exemplified by the "double anchor" shape. Critical to production of the pre-specified fibers with complex features was independent control over both the shape and the size of the fabricated microfibers using a two-stage hydrodynamic focusing system. Design and optimization of the channels was performed using finite element simulations and confocal imaging to characterize each of the two stages theoretically and experimentally. The resulting device design was then used to generate thiol-ene fibers with a unique double anchor shape. Finally, proof-of-principle functional experiments demonstrated the ability of the fibers to transport fluids and to interlock laterally.

  12. Ära söö kiles saia ehk kas poliitilist kunsti on võimalik mõista? = Do not eat white bread in plastic, or is it possible to understand political art? / Ene-Liis Semper, Eero Epner

    Semper, Ene-Liis, 1969-

    2006-01-01

    Poliitillisest teatrist. NO99 lavastusest "Nafta" (lavastajad, autorid: Tiit Ojasoo, Ene-Liis Semper, kunstnik Ene-Liis Semper). Ettekanne Kaasaegse Kunsti Eesti Keskuse 4. ettekannete päeval "Kunstnike moraalsed valikud kultuurikonfliktides" Tallinna Kunstihoones 27.04.2006. Bibliograafia lk. 112

  13. Assessment of the role of in situ generated (E)-2,4-diene-valproic acid in the toxicity of valproic acid and (E)-2-ene-valproic acid in sandwich-cultured rat hepatocytes

    Surendradoss, Jayakumar; Chang, Thomas K.H.; Abbott, Frank S., E-mail: frank.abbott@ubc.ca

    2012-11-01

    Valproic acid (VPA) undergoes cytochrome P450-mediated desaturation to form 4-ene-VPA, which subsequently yields (E)-2,4-diene-VPA by β-oxidation. Another biotransformation pathway involves β-oxidation of VPA to form (E)-2-ene-VPA, which also generates (E)-2,4-diene-VPA by cytochrome P450-mediated desaturation. Although the synthetic form of (E)-2,4-diene-VPA is more hepatotoxic than VPA as shown in various experimental models, there is no conclusive evidence to implicate the in situ generated (E)-2,4-diene-VPA in VPA hepatotoxicity. The present study investigated the effects of modulating the in situ formation of (E)-2,4-diene-VPA on markers of oxidative stress (formation of 2′,7′-dichlorofluorescein; DCF), steatosis (accumulation of BODIPY 558/568 C{sub 12}), necrosis (release of lactate dehydrogenase; LDH), and on cellular total glutathione (GSH) levels in sandwich-cultured rat hepatocytes treated with VPA or (E)-2-ene-VPA. Treatment with either of these chemicals alone increased each of the toxicity endpoints. In VPA-treated hepatocytes, (E)-2,4-diene-VPA was detected only at trace levels, even after phenobarbital (PB) pretreatment and there was no effect on the toxicity of VPA. Furthermore, pretreatment with a cytochrome P450 enzyme inhibitor, 1-aminobenzotriazole (1-ABT), did not influence the extent of VPA toxicity in both PB-pretreated and vehicle-pretreated hepatocytes. However, in (E)-2-ene-VPA-treated hepatocytes, PB pretreatment greatly enhanced the levels of (E)-2,4-diene-VPA and this was accompanied by a further enhancement of the effects of (E)-2-ene-VPA on DCF formation, BODIPY accumulation, LDH release, and GSH depletion. Pretreatment with 1-ABT reduced the concentrations of (E)-2,4-diene-VPA and the extent of (E)-2-ene-VPA toxicity; however, this occurred in PB-pretreated hepatocytes, but not in control hepatocytes. In conclusion, in situ generated (E)-2,4-diene-VPA is not responsible for the hepatocyte toxicity of VPA, whereas it

  14. Novel Anti-Biofouling Soft Contact Lens: l-Cysteine Conjugated Amphiphilic Conetworks via RAFT and Thiol-Ene Click Chemistry.

    Zhang, Chengfeng; Liu, Ziyuan; Wang, Haiye; Feng, Xiaofeng; He, Chunju

    2017-07-01

    A unique l-cysteine conjugated antifouling amphiphilic conetwork (APCN) is synthesized through end-crosslinking of well-defined triblock copolymers poly(allyl methacrylate)-b-poly(ethylene glycol)-b-poly(allyl methacrylate) via a combination of reversible addition-fragmentation chain transfer (RAFT) polymerization and thiol-ene "click" chemistry. The synthesized poly(ethylene glycol) macro-RAFT agent initiates the polymerization of allyl methacrylate in a controlled manner. The vinyl pendant groups of the precursor partially conjugate with l-cysteine and the rest fully crosslink with mercaptopropyl-containing siloxane via thiol-ene click chemistry under UV irradiation into APCNs, which show distinguished properties, that is, excellent biocompatibility, more than 39.6% water content, 101 barrers oxygen permeability, optimized mechanical properties, and more than 93% visible light transmittance. What's more, the resultant APCNs exhibit eminent resistance to protein adsorption, where the bovine serum albumin and lysozyme adsorption are decreased to 12 and 21 µg cm -2 , respectively. The outstanding properties of APCNs depend on the RAFT controlled method, which precisely designs the hydrophilic/hydrophobic segments and eventually greatly improves the crosslinking efficiency and homogeneity. Meantime, the l-cysteine monolayer can effectively reduce the surface hydrophobicity and prevent protein adsorption, which exhibits the viability for antifouling surface over and under ophthalmic devices, suggesting a promising soft contact lens. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  15. Synthesis of Upconverting Hydrogel Nanocomposites Using Thiol-Ene Click Chemistry: Template for the Formation of Dendrimer-Like Gold Nanoparticle Assemblies.

    Meesaragandla, Brahmaiah; Mahalingam, Venkataramanan

    2015-11-16

    The synthesis of upconverting hydrogel nanocomposites by base-catalyzed thiol-ene click reaction between 10-undecenoic acid capped Yb(3+)/Er(3+)-doped NaYF4 nanoparticles and pentaerythritol tetrakis(3-mercaptopropionate) (PETMP) as tetrathiol monomer is reported. This synthetic strategy for nanocomposite gels is quite different from works where usually the preformed gels are mixed with the nanoparticles. Developing nanocomposites by surface modification of capping ligands would allow tuning and controlling of the separation of the nanoparticles inside the gel network. The hydrogel nanocomposites prepared by thiol-ene click reaction show strong enhancement in luminescence intensity compared to 10-undecenoic acid-capped Yb(3+)/Er(3+)-doped NaYF4 nanoparticles through the upconversion process (under 980 nm laser excitation). The hydrogel nanocomposites display strong swelling characteristics in water resulting in porous structures. Interestingly, the resulting nanocomposite gels act as templates for the synthesis of dendrimer-like Au nanostructures when HAuCl4 is reduced in the presence of the nanocomposite gels. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. Pyriculins A and B, two monosubstituted hex-4-ene-2,3-diols and other phytotoxic metabolites produced by Pyricularia grisea isolated from buffelgrass (Cenchrus ciliaris).

    Masi, Marco; Meyer, Susan; Górecki, Marcin; Mandoli, Alessandro; Di Bari, Lorenzo; Pescitelli, Gennaro; Cimmino, Alessio; Cristofaro, Massimo; Clement, Suzette; Evidente, Antonio

    2017-11-01

    Pyricularia grisea has been identified as a foliar pathogen on buffelgrass (Cenchrus ciliaris) in North America and was studied as a potential source of phytotoxins for buffelgrass control. Two monosubstituted hex-4-ene-2,3-diols, named pyriculins A and B, were isolated from its culture filtrate organic extract together with (10S,11S)-(-)-epipyriculol, trans-3,4-dihydro-3,4,8-trihydroxy-1(2H)-napthalenone, and (4S)-(+)-isosclerone. Pyriculins A and B were characterized by spectroscopic (essentially nuclear magnetic resonance [NMR], High-resolution electrospray ionization mass spectrometry [HRESIMS]) and chemical methods such as (4E)-1-(4-hydroxy-1,3-dihydroisobenzofuran-1-yl)hex-4-ene-2,3-diols. The relative and absolute configuration of these compounds was determined by a combination of spectroscopic (NMR, electronic circular dichroism [ECD]) and computational tools. When bioassayed in a buffelgrass coleoptile and radicle elongation test, (10S,11S)-(-)-epipyriculol proved to be the most toxic compound. Seed germination was much reduced and slowed with respect to the control and radicles failed to elongate. All five compounds delayed germination, but only (10S,11S)-(-)-epipyriculol was able to prevent radicle development of buffelgrass seedlings. It had no effect on coleoptile elongation, while the other four compounds caused significantly increased coleoptile development relative to the control. © 2017 Wiley Periodicals, Inc.

  17. Grunge kodukujunduses / Ene Vool

    Vool, Ene, 1948-

    2004-01-01

    Low-tech, campi ja grunge ehitus- ja sisustusstiilidest meil ja mujal - kommenteerivad Andro Kööp ja Ain Nurmela. Tutvustatakse ka Mari-Mira projekti Pariisis, mis kujutab endast nn. mutant-küla, putka- ja onnikultuuri koketeriid. Artikli lõpus kommenteerib kunstiteadlane Karin Paulus grungestiili muusikas, riietuses ja sisekujunduses.

  18. Taevo Gans / Ene Ammer

    Ammer, Ene

    1998-01-01

    Sisearhitekt Taevo Gansist. Tudengipõlvest, selle aja projektidest, sõpruskonnast, tandemist Summatavet & Gans, Venemaa tellimustest, kaastöölistest. Üksinda Hommilkumaal vene tarbekunsti näitusega 1974. a. 1988. a. loodud perefirmast "GaDis" (omanikud Taevo, Helle Gans, Riia Oja), mis nõustab ka "Wermot" mööbli osas. "GaDise" sisekujundusprojektidest, millega Taevo ja Helle Gans tegelevad üheskoos

  19. Repliik / Ene Pajula

    Pajula, Ene, 1950-

    2008-01-01

    Õpilaskodude foorumist ja õpilaskodudest, mis on loodud kodanikualgatuse korras ja nende inimeste tunnustamise vajadusest, tänu kellele meil on kakskümmend kaheksa õpilaskodu, kus elule tagasi võidetud saab nii mõnigi laps

  20. Whats 'App-ening'

    Ankersen, Dorit V; Weimers, Petra; Burisch, Johan

    2017-01-01

    in number. ehealth helps patients in coping with their disease by promoting self-management, which increases adherence to medical treatment and diets, and leads to an improved quality of life. For irritable bowel syndrome (IBS), there are multiple applications that provide dietary advice, for example, a low...

  1. Limitations of the Neurological Evolutional Exam (ENE as a motor assessment for first graders Limitações do Exame Neurológico Evolutivo (ENE como um instrumento de avaliação motora para crianças da primeira série

    Priscila M. Caçola

    2010-10-01

    Full Text Available BACKGROUND: Many clinicians and researchers in Brazil consider the Neurological Developmental Exam (NDE, a valid and reliable assessment for Brazilian school-aged children. However, since its inception, several tests have emerged that, according to some researchers, provide more in-depth evaluation of motor ability and go beyond the detection of general motor status (soft neurological signs. OBJECTIVES: To highlight the limitations of the NDE as a motor skill assessment for first graders. METHODS: Thirty-five children were compared on seven selected items of the NDE, seven of the Bruininks-Oseretsky Test (BOT, and seven of the Visual-Motor Integration test (VMI. Participants received a "pass" or "fail" score for each item, as prescribed by the respective test manual. RESULTS: Chi-square and ANOVA results indicated that the vast majority of children (74% passed the NDE items, whereas values for the other tests were 29% (BOT and 20% (VMI. Analysis of specific categories (e.g. visual, fine, and gross motor coordination revealed a similar outcome. CONCLUSIONS: Our data suggest that while the NDE may be a valid and reliable test for the detection of general motor status, its use as a diagnostic/remedial tool for identifying motor ability is questionable. One of our recommendations is the consideration of a revised NDE in light of the current needs of clinicians and researchers.CONTEXTUALIZAÇÃO: Muitos clínicos e pesquisadores brasileiros consideram o Exame Neurológico Evolutivo (ENE, um instrumento válido e confiável para crianças brasileiras em idade escolar. Entretanto, desde a sua criação, surgiram outros testes para uma avaliação mais profunda de habilidade motora, os quais vão além de detectar status motor geral em forma de sinais neurológicos leves. OBJETIVOS: Demonstrar os pontos fracos do ENE como teste de avaliação de habilidade motora para crianças de primeira série. MÉTODOS: Trinta e cinco crianças realizaram 7 itens

  2. The photochemical reaction of 1,1-dicyano-3-phenylbut-1-ene. Simultaneous occurrence of p-methane and di-p-methane rearrangements

    Silva Francisco A. da

    1999-01-01

    Full Text Available The direct photolysis of 1,1-dicyano-3-phenylbut-1-ene (3-MDCN was investigated at room temperature in solvents of different polarities (hexane, dichloromethane and acetonitrile. Cyclopropanes arising from both the di-pi-methane and pi-methane (1,2-H migration processes were obtained as photoproducts. The structures of the products were elucidated by ¹H-NMR, GC/MS, IR and chromatography. Relative quantum yield determination and GC analysis of sequential irradiations gave evidence that: i no secondary reactions occur, even at high conversions; ii the di-pi-methane rearrangement is significantly more affected by the solvent variation than the pi-methane reaction. Photosensitization with acetophenone or acetone did not yield any observable products. The existence of the simultaneous mechanisms and the observed effects were considered as evidence of a possible differentiation between localized and delocalized excitation on the excited state surface.

  3. Enantioselective synthesis of possible diastereomers of heptadeca-1-ene-4,6-diyne-3,8,9,10-tetrol; putative structure of a conjugated diyne natural product isolated from Hydrocotyle leucocephala.

    Prasad, Kavirayani R; Swain, Bandita

    2011-04-01

    Enantioselective synthesis of possible diastereomers of heptadeca-1-ene-4,6-diyne-3,8,9,10-tetrol, a structure proposed for the natural product isolated from Hydrocotyle leucocephala is accomplished. The reported spectral data of the natural product did not match those of any of the isomers that were synthesized and established that the structure proposed for the natural product is not correct and requires revision.

  4. IN0523 (Urs-12-ene-3α,24β-diol) a plant based derivative of boswellic acid protect Cisplatin induced urogenital toxicity

    Singh, Amarinder; Arvinda, S; Singh, Surjeet; Suri, Jyotsna; Koul, Surinder; Mondhe, Dilip M.; Singh, Gurdarshan; Vishwakarma, Ram

    2017-01-01

    The limiting factor for the use of Cisplatin in the treatment of different type of cancers is its toxicity and more specifically urogenital toxicity. Oxidative stress is a well-known phenomenon associated with Cisplatin toxicity. However, in Cisplatin treated group, abnormal animal behavior, decreased body weight, cellular and sub-cellular changes in the kidney and sperm abnormality were observed. Our investigation revealed that Cisplatin when administered in combination with a natural product derivative (Urs-12-ene-3α,24β-diol, labeled as IN0523) resulted in significant restoration of body weight and protection against the pathological alteration caused by Cisplatin to kidney and testis. Sperm count and motility were significantly restored near to normal. Cisplatin caused depletion of defense system i.e. glutathione peroxidase, catalase and superoxide dismutase, which were restored close to normal by treatment of IN0523. Reduction in excessive lipid peroxidation induced by Cisplatin was also found by treatment with IN0523. The result suggests that IN0523 is a potential candidate for ameliorating Cisplatin induced toxicity in the kidney and testes at a dose of 100 mg/kg p.o. via inhibiting the oxidative stress/redox status imbalance and may be improving the efflux mechanism. - Highlights: • Synthesis of a novel boswellic acid derivative (IN0523) • Counter oxidative stress induced due to Cisplatin • Protect against urogenital toxicity induced by Cisplatin

  5. Occurrence of (Z)-3,4-Dideoxyglucoson-3-ene in Different Types of Beer and Malt Beer as a Result of 3-Deoxyhexosone Interconversion.

    Hellwig, Michael; Nobis, Arndt; Witte, Sophia; Henle, Thomas

    2016-04-06

    In beer, 3-deoxyglucosone (3-DG) and 3-deoxygalactosone (3-DGal) are important sugar degradation products, but little is known about the relevance of the interconversion reaction between these compounds in different types of beer. In the present study, 3-DG was quantitated at concentrations of 12.9-52.7 mg/L and 3-DGal at concentrations of 6.0-26.4 mg/L in different types of beer (pilsner, wheat, bock, dark, and alcohol-free beers). The concentrations in malt beer tended to be higher. Largely overlapping concentration ranges precluded a classification of beers by their 3-deoxyglycosone contents. 3,4-Dideoxyglucoson-3-ene (3,4-DGE) was identified as an important intermediate and quantitated in beer and malt beer for the first time. The E and Z isomers of the corresponding quinoxaline were synthesized by a new synthetic approach and isolated by semipreparative HPLC. An assay was developed for quantitation of (E)- and (Z)-3,4-DGE by HPLC-MS/MS, and the Z isomer was determined at concentrations of 0.3-1.7 mg/L in beer and 0.5-4.8 mg/L in malt beer samples. The E isomer was shown to be of little importance. Concentrations of 5-hydroxymethylfurfural (HMF) were twice as high as those of (Z)-3,4-DGE in beer samples (0.4-3.7 mg/L) but much higher in malt beer samples (1.6-336 mg/L).

  6. The synthesis of weak acidic type hybrid monolith via thiol-ene click chemistry and its application in hydrophilic interaction chromatography.

    Zeng, Jiao; Liu, Shengquan; Wang, Menglin; Yao, Shouzhuo; Chen, Yingzhuang

    2017-05-01

    In this work, a porous structure and good permeability monolithic column was polymerized in UV transparent fused-silica capillaries via photo-initiated thiol-ene click polymerization of 2,4,6,8-tetravinyl-2,4,6,8-tetramethylcyclotetrasiloxane (TMTVS), pentaerythritol tetra(3-mercaptopropionate)(PETMP), itaconic acid, respectively, in the presence of porogenic solvents (tetrahydrofuranand methanol) and an initiator (2,2-dimethoxy-2-phenylacetophenone) (DMPA) within 30 min. The physical properties of this monolith were characterized by scanning electron microscopy (SEM), Fourier transform infrared (FT-IR) spectroscopy and nitrogen adsorption/desorption measurements. For an overall evaluation of the monolith in chromatographic application, separations of polycyclic aromatic hydrocarbons (PAHs), phenols, amides and bases were carried out. The column efficiency of this monolith could be as high as 112 560 N/m. It also possesses a potential application in fabrication of monoliths with high efficiency for c-LC. In addition, the resulting monolithic column demonstrated the potential use in analysis of environment waters. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. Thiol-ene immobilisation of carbohydrates onto glass slides as a simple alternative to gold-thiol monolayers, amines or lipid binding.

    Biggs, Caroline I; Edmondson, Steve; Gibson, Matthew I

    2015-01-01

    Carbohydrate arrays are a vital tool in studying infection, probing the mechanisms of bacterial, viral and toxin adhesion and the development of new treatments, by mimicking the structure of the glycocalyx. Current methods rely on the formation of monolayers of carbohydrates that have been chemically modified with a linker to enable interaction with a functionalised surface. This includes amines, biotin, lipids or thiols. Thiol-addition to gold to form self-assembled monolayers is perhaps the simplest method for immobilisation as thiolated glycans are readily accessible from reducing carbohydrates in a single step, but are limited to gold surfaces. Here we have developed a quick and versatile methodology which enables the use of thiolated carbohydrates to be immobilised as monolayers directly onto acrylate-functional glass slides via a 'thiol-ene'/Michael-type reaction. By combining the ease of thiol chemistry with glass slides, which are compatible with microarray scanners this offers a cost effective, but also useful method to assemble arrays.

  8. Poly(allyl methacrylate) functionalized hydroxyapatite nanocrystals via the combination of surface-initiated RAFT polymerization and thiol-ene protocol: a potential anticancer drug nanocarrier.

    Bach, Long Giang; Islam, Md Rafiqul; Vo, Thanh-Sang; Kim, Se-Kwon; Lim, Kwon Taek

    2013-03-15

    Hydroxyapatite nanocrystals (HAP NCs) were encapsulated by poly(allyl methacrylate) (PolyAMA) employing controlled surface-initiated reversible addition-fragmentation chain transfer (SI-RAFT) polymerization of allyl methacrylate to afford HAP-PolyAMA nanohybrids. The subsequent thiol-ene coupling of nanohybrids with 2-mercaptosuccinic acid resulted HAP-Poly(AMA-COOH) possessing multicarboxyl group. The formation of the nanohybrids was confirmed by FT-IR and EDS analyses. The TGA and FE-SEM investigation were further suggested the grafting of PolyAMA onto HAP NCs. The utility of the HAP-PolyAMA nanohybrid as drug carrier was also explored. The pendant carboxyl groups on the external layers of nanohybrids were conjugated with anticancer drug cisplatin to afford HAP-Poly(AMA-COOH)/Pt complex. The formation of the complex was confirmed by FT-IR, XPS, and FE-SEM. In vitro evaluation of the synthesized complex as nanomedicine revealed its potential chemotherapeutic efficacy against cancer cell lines. Copyright © 2012 Elsevier Inc. All rights reserved.

  9. Synthesis of Pyridine and Spiropyridine Derivatives Derived from 2-aminoprop- 1-ene-1,1,3-tricarbonitrile Together with their c-Met Kinase and Antiproliferative Evaluations.

    Mohareb, Rafat M; Abouzied, Amr S; Abbas, Nermeen S

    2018-02-07

    Among a wide range of pyridines, 3-cyanopyridines acquired a special attention due to their wide range of pharmacological activities especially the therapeutic activities. Many pharmacological drugs containing the pyridine nucleus were known in the market. The aim of this work was to synthesize target molecules not only possess anti-tumor activities but also kinase inhibitors. To achieve this goal, our strategy was to synthesize a series of 3-cyanopyridine derivatives using 2-aminoprop-1-ene-1,1,3-tricarbonitrile (1) as the key starting material for many heterocyclization reactions. Muticoponent reactions were adopted using compound 1 to get different pyridine derivatives that were capable for different heterocyclization reactions. Antiproliferative evaluations and c-Met kinase, Pim-1 kinse inhibitions were perform where some compounds gave high activities. Compounds that showed high antiprolifeative activity were tested gor c-Met-independent and the results showed that compounds 5c, 5e, 5f, 7c, 7f and 16d were more active than foretinib. The Pim-1 kinase inhibition activity of some selected compounds showed that compounds 5e and 16c were high potent to inhibit Pim-1 activity. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  10. Properties of solid electrolyte interphase formed by prop-1-ene-1,3-sultone on graphite anode of Li-ion batteries

    Li, Bin; Xu, Mengqing; Li, Benzhen; Liu, Yanlin; Yang, Liang; Li, Weishan; Hu, Shejun

    2013-01-01

    Highlights: • SEI formed by PES on NG was characterized with charge/discharge test, SEM, FTIR, and XPS. • NG in PC-based electrolyte can be well protected using PES. • Sulfur-containing species is the main component of the SEI formed by PES. • Preferable reduction of PES results in the formation of protective SEI on NG. -- Abstract: The physical and chemical properties of the solid electrolyte interphase (SEI) formed by prop-1-ene-1,3-sultone (PES) on graphite anode in propylene carbonate (PC) based electrolyte for lithium ion battery were investigated by charge–discharge test, scanning electron spectroscopy with energy dispersive X-ray spectroscopy (SEM–EDS), Fourier transform infrared spectroscopy (FTIR), and X-ray photoelectron spectroscopy (XPS). It is found that the charge–discharge performance of the cell LiCoO 2 /natural graphite (NG) using PC-based electrolyte containing 3 wt% PES is superior to that containing 6 wt% propane sultone (PS), an SEI formation additive that has the similar molecular structure to PES but is reduced not as easily as PES. The results from SEM–EDS, FTIR and XPS show that the structure of graphite has been protected and some S-containing species are proven to be components of the SEI, suggesting that the preferable reduction of PES plays an important role in the formation of a protective SEI on NG

  11. IN0523 (Urs-12-ene-3α,24β-diol) a plant based derivative of boswellic acid protect Cisplatin induced urogenital toxicity

    Singh, Amarinder [Academy of Scientific & Innovative Research (AcSIR), New Delhi (India); PK-PD-Toxicology and Formulation Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, J& K (India); Arvinda, S [Deptt. of Pathology, Govt. Medical College, Jammu 180001, J& K (India); Singh, Surjeet [PK-PD-Toxicology and Formulation Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, J& K (India); Suri, Jyotsna [Deptt. of Pathology, Govt. Medical College, Jammu 180001, J& K (India); Koul, Surinder [Bio-Organic Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, J& K (India); Mondhe, Dilip M. [Cancer Pharmacology Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, J& K (India); Singh, Gurdarshan, E-mail: singh_gd@iiim.ac.in [PK-PD-Toxicology and Formulation Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, J& K (India); Vishwakarma, Ram [Bio-Organic Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, J& K (India)

    2017-03-01

    The limiting factor for the use of Cisplatin in the treatment of different type of cancers is its toxicity and more specifically urogenital toxicity. Oxidative stress is a well-known phenomenon associated with Cisplatin toxicity. However, in Cisplatin treated group, abnormal animal behavior, decreased body weight, cellular and sub-cellular changes in the kidney and sperm abnormality were observed. Our investigation revealed that Cisplatin when administered in combination with a natural product derivative (Urs-12-ene-3α,24β-diol, labeled as IN0523) resulted in significant restoration of body weight and protection against the pathological alteration caused by Cisplatin to kidney and testis. Sperm count and motility were significantly restored near to normal. Cisplatin caused depletion of defense system i.e. glutathione peroxidase, catalase and superoxide dismutase, which were restored close to normal by treatment of IN0523. Reduction in excessive lipid peroxidation induced by Cisplatin was also found by treatment with IN0523. The result suggests that IN0523 is a potential candidate for ameliorating Cisplatin induced toxicity in the kidney and testes at a dose of 100 mg/kg p.o. via inhibiting the oxidative stress/redox status imbalance and may be improving the efflux mechanism. - Highlights: • Synthesis of a novel boswellic acid derivative (IN0523) • Counter oxidative stress induced due to Cisplatin • Protect against urogenital toxicity induced by Cisplatin.

  12. IN0523 (Urs-12-ene-3α,24β-diol) a plant based derivative of boswellic acid protect Cisplatin induced urogenital toxicity.

    Singh, Amarinder; Arvinda, S; Singh, Surjeet; Suri, Jyotsna; Koul, Surinder; Mondhe, Dilip M; Singh, Gurdarshan; Vishwakarma, Ram

    2017-03-01

    The limiting factor for the use of Cisplatin in the treatment of different type of cancers is its toxicity and more specifically urogenital toxicity. Oxidative stress is a well-known phenomenon associated with Cisplatin toxicity. However, in Cisplatin treated group, abnormal animal behavior, decreased body weight, cellular and sub-cellular changes in the kidney and sperm abnormality were observed. Our investigation revealed that Cisplatin when administered in combination with a natural product derivative (Urs-12-ene-3α,24β-diol, labeled as IN0523) resulted in significant restoration of body weight and protection against the pathological alteration caused by Cisplatin to kidney and testis. Sperm count and motility were significantly restored near to normal. Cisplatin caused depletion of defense system i.e. glutathione peroxidase, catalase and superoxide dismutase, which were restored close to normal by treatment of IN0523. Reduction in excessive lipid peroxidation induced by Cisplatin was also found by treatment with IN0523. The result suggests that IN0523 is a potential candidate for ameliorating Cisplatin induced toxicity in the kidney and testes at a dose of 100mg/kg p.o. via inhibiting the oxidative stress/redox status imbalance and may be improving the efflux mechanism. Copyright © 2017 Elsevier Inc. All rights reserved.

  13. Critical Parameters and Critical-Region (p,ρ ,T) Data of trans-1,1,1,3-Tetrafluorobut-2-ene [HFO-1354mzy(E)

    Kimura, Takeru; Kayukawa, Yohei; Miyamoto, Hiroyuki; Saito, Kiyoshi

    2017-08-01

    This study presents the experimental measurement of the pρ T properties and critical parameters of a low GWP type refrigerant, trans-1,1,1,3-Tetrafluorobut-2-ene (HFO-1354mzy(E)). The sample purity of the substance was 99 area %. p ρ T property measurements and visual observations of the meniscus of HFO-1354mzy(E) were carried out using a metal-bellows volumometer with an optical cell. The critical temperature was determined by observation of the critical opalescence. The critical pressure and critical density were determined as the inflection point of the isothermal p ρ T property data at the critical temperature. For more precise clarification of the thermodynamic surface in the vicinity of the critical point, additional p ρ T property measurements were carried out on three isotherms in the supercritical region. The expanded uncertainties (k = 2) in the temperature, pressure, and density measurements were estimated to be less than 3 mK, 1.2 kPa, and 0.32 \\hbox {kg} \\cdot \\hbox {m}^{-3}, respectively. The expanded uncertainties of the critical parameters were estimated to be less than 13 mK, 1.4 kPa, and 2.3 \\hbox {kg} \\cdot \\hbox {m}^{-3}, respectively. These values are the first reported for HFO-1354mzy(E) and are necessary for the development of its equation of state in the near future.

  14. Reaction of singlet-excited 2,3-diazabicyclo[2.2.2]oct-2-ene and tert-butoxyl radicals with aryl-substituted benzofuranones.

    Lundgren, Cecilia Vannesjö; Koner, Apurba L; Tinkl, Michael; Pischel, Uwe; Nau, Werner M

    2006-03-03

    5,7-Di-tert-butyl-3-aryl-3H-benzofuran-2-ones are lactones with potential antioxidant activity, owing to their abstractable benzylic C-H hydrogens. The fluorescence quenching of the azoalkane 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO), an established probe for the hydrogen-donor propensity of chain-breaking antioxidants, was investigated for 16 aryl-substituted benzofuranone derivatives [m,m-(CF3)2, p-CN, m-CN, p-CF3, p-COOCH3, m-CF3, p-Cl, p-F, H, m-CH3, p-CH3, m,p-(CH3)2, p-OCH3, o-CH3, o-CF3, o,m-(CH3)2]. Analysis of the rate data in terms of a linear free energy relationship yielded a reaction constant of rho = +0.35. This implies that n,pi*-excited DBO acts as nucleophilic species. In contrast, hydrogen abstraction of tert-butoxyl radicals from the benzofuranones was accelerated by electron-donating substituents (rho = -0.23), in conformity with the electrophilic character of oxygen-centered alkoxyl radicals. Possible implications for the optimization of the hydrogen-donor propensity of antioxidants through structural variation are discussed.

  15. Investigation of the fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) by certain substituted uracils

    Anbazhagan, V. [School of Chemistry, Bharathidasan University, Tiruchirappalli 620024, Tamil Nadu (India); Renganathan, R. [School of Chemistry, Bharathidasan University, Tiruchirappalli 620024, Tamil Nadu (India)], E-mail: rrengas@yahoo.com

    2009-04-15

    The fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) by a series of uracils has been studied in water and acetonitrile solvents using steady-state and time-resolved fluorescence techniques. The steady-state fluorescence quenching technique has been performed in three different pHs (i.e. 4, 8 and 12). The bimolecular quenching rate constant (k{sub q}) increases with increase in pH of uracils. In acidic pH, a pure hydrogen atom abstraction is proposed as the quenching mechanism. This is supported by a pronounced solvent deuterium isotope effect. Electron transfer from the anionic form of uracil to the excited state of DBO is proposed as a mechanism for quenching in basic pH on the basis of highly exergonic thermodynamics obtained from the Rehm-Weller equation. The variation of k{sub q} is explained on the basis of the electronic effect of substitution in uracils as well.

  16. Investigation of the fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) by certain substituted uracils

    Anbazhagan, V.; Renganathan, R.

    2009-01-01

    The fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) by a series of uracils has been studied in water and acetonitrile solvents using steady-state and time-resolved fluorescence techniques. The steady-state fluorescence quenching technique has been performed in three different pHs (i.e. 4, 8 and 12). The bimolecular quenching rate constant (k q ) increases with increase in pH of uracils. In acidic pH, a pure hydrogen atom abstraction is proposed as the quenching mechanism. This is supported by a pronounced solvent deuterium isotope effect. Electron transfer from the anionic form of uracil to the excited state of DBO is proposed as a mechanism for quenching in basic pH on the basis of highly exergonic thermodynamics obtained from the Rehm-Weller equation. The variation of k q is explained on the basis of the electronic effect of substitution in uracils as well

  17. Crystal and Molecular Structure Studies of Ethyl 4-(4-Hydroxyphenyl-6-(6-methoxy-2-naphthyl-2-oxocyclohex-3-ene-1-carboxylate and Ethyl 4-(3-Bromophenyl-6-(6-methoxy-2-naphthyl-2-oxocyclohex-3-ene-1-carboxylate

    Badiadka Narayana

    2012-08-01

    Full Text Available The crystal and molecular structures of the title compounds, ethyl 4-(4-hydroxyphenyl-6-(6-methoxy-2-naphthyl-2-oxocyclohex-3-ene-1-carboxylate (I and ethyl 4-(3-bromophenyl-6-(6-methoxy-2-naphthyl-2-oxocyclohex-3-ene-1-carboxylate (II, are reported and confirmed by single crystal X-ray diffraction data. Compound (I, C26H24O5, crystallizes from a methanol solution in the monoclinic C2/c space group with eight molecules in the unit cell. The unit cell parameters are: a = 25.4114(5 Å, b = 8.47440(10 Å, c = 20.6921(4 Å, β = 108.328(2° and V = 4229.92(13 Å3. Disorder is observed throughout the entire molecule with an occupancy ratio 0.690(2:0.310(2. Compound (II, C26H23O4Br, crystallizes from an ethyl acetate solution in the monoclinic P21/c spacegroup with four molecules in the unit cell. The unit cell parameters are a = 17.8991(9 Å, b = 11.4369(6 Å, c = 10.8507(5 Å, β = 92.428(4° and V = 2219.25(19 Å3. Disorder is observed in the cyclohexenone ring and the carboxylate group with an occupancy ratio 0.830(6:0.170(6. Weak O–H...O (I or C–H...O (II intermolecular interactions are observed which influence crystal packing stability. These chalcone derivative types of molecules are important in their ability to act as activated unsaturated systems in conjugated addition reactions of carbanions in the presence of basic catalysts which exhibit a multitude of biological activities.

  18. C60 and Sc3N@C80(TMB-PPO derivatives as constituents of singlet oxygen generating, thiol-ene polymer nanocomposites

    Ashli R. Toles

    2016-07-01

    Full Text Available Numerous functionalization methods have been employed to increase the solubility, and therefore, the processability of fullerenes in composite structures, and of these radical addition reactions continue to be an important methodology. C60 and Sc3N@C80 derivatives were prepared via radical addition of the photodecomposition products from the commercial photoinitiator TMB-PPO, yielding C60(TMB-PPO5 and Sc3N@C80(TMB-PPO3 as preferred soluble derivatives obtained in high yields. Characterization of the mixture of isomers using standard techniques suggests an overall 1PPO:6TMB ratio of addends, reflecting the increased reactivity of the carbon radical. Although, a higher percentage of PPO is observed in the Sc3N@C80(TMB-PPO3 population, perhaps due to reverse electronic requirements of the substrate. Visually dispersed thiol-ene nanocomposites with low extractables were prepared using two monomer compositions (PETMP:TTT and TMPMP:TMPDE with increasing fullerene derivative loading to probe network structure-property relationships. Thermal stability of the derivatives and the resulting networks decreased with increased functionality and at high fullerene loadings, respectively. TMPMP:TMPDE composite networks show well-dispersed derivatives via TEM imaging, and increasing Tg’s with fullerene loading, as expected for the incorporation of a more rigid network component. PETMP:TTT composites show phase separation in TEM, which is supported by the observed Tg’s. Singlet oxygen generation of the derivatives decreases with increased functionality; however, this is compensated for by the tremendous increase in solubility in organic solvents and miscibility with monomers. Most importantly, singlet oxygen generation from the composites increased with fullerene derivative loading, with good photostability of the networks.

  19. Spectral behavior and photophysical parameters of (2Z)-3-[4-(dimethylamino) phenyl]-2-(4-fluorophenyl) prop-2-ene-nitrile (DPF) in different media

    Pannipara, Mehboobali [Department of Chemistry, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589 (Saudi Arabia); Asiri, Abdullah M. [Department of Chemistry, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589 (Saudi Arabia); Center of Excellence for Advanced Materials Research, King Abdulaziz University, Jeddah 21589, P.O. Box 80203 (Saudi Arabia); Alamry, Khalid A. [Department of Chemistry, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589 (Saudi Arabia); Salem, Ibrahim A. [Department of Chemistry, Faculty of Science, Tanta University, 31527 Tanta (Egypt); El-Daly, Samy A., E-mail: samyeldaly@yahoo.com [Department of Chemistry, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589 (Saudi Arabia); Department of Chemistry, Faculty of Science, Tanta University, 31527 Tanta (Egypt)

    2015-01-15

    A new fluorophore, (2Z)-3-[4-(dimethylamino) phenyl]-2-(4-fluorophenyl) prop-2-ene-nitrile (DPF), was synthesized by knoevenagel condensation of 4-(dimethylamino) benzaldehyde and 4-fluorobenzyl cyanide in ethanol using NaOH as base. The electronic absorption and emission characteristic of DPF were studied in different solvents. The X-ray crystallographic structure of DPF was also investigated. DPF exhibits a red-shift in its emission spectrum as solvent polarity increases, indicating a large change in the dipole moment of dye molecule upon excitation due to intramolecular charge transfer in excited DPF{sup ⁎}. The fluorescence quantum yield depends strongly on the properties of the solvents, which was attributed to positive and negative solvatokinetic effects. A crystalline solid of DPF gives a strong yellow emission at about 532 nm; these phenomena are important for the application of DPF dye in organic photoemitting diode. The photochemical quantum yield of cis–trans isomerization of DPF was also determined in different solvents. The DPF dye displays solubilization in both cationic (CTAB) and anionic (SDS) micelle and may be used as a probe to determine the critical micelle concentration (CMC) of SDS and CTAB. - Highlights: • Organic pi conjugated molecule with a donor acceptor group was studied. • Crystalline solid of the molecule shows strong and intense yellow emission. • The dye displays solubilization in cationic micelle with abrupt change in emission intensity at CMC. • This work gives an insight into the application of organic luminescent material in various fields.

  20. Design of peptide substrates for nanosecond time-resolved fluorescence assays of proteases: 2,3-diazabicyclo[2.2.2]oct-2-ene as a noninvasive fluorophore.

    Hennig, Andreas; Florea, Mara; Roth, Doris; Enderle, Thilo; Nau, Werner M

    2007-01-15

    Fluorescence protease assays were investigated with peptide substrates containing a 2,3-diazabicyclo[2.2.2]oct-2-ene-labeled asparagine (Dbo) as a fluorescent amino acid. The special characteristic of the fluorophore Dbo is its exceedingly long fluorescence lifetime (ca. 300 ns in water under air), which allows the use of nanosecond time-resolved fluorescence (Nano-TRF) detection to efficiently suppress shorter-lived background emission. In addition, the natural amino acids tryptophan and tyrosine can be employed as intramolecular fluorescence quenchers, which facilitates substrate design. Fourteen synthetic peptide substrates (composed of 2-19 amino acids) and five enzymes (trypsin, pepsin, carboxypeptidase A, leucine aminopeptidase, and chymotrypsin) were investigated and, in all 28 examined combinations, enzymatic activity was detected by monitoring the increase in steady state fluorescence with time and determining the reaction rates as kcat/Km values, which ranged from 0.2 to 80x10(6) M-1 min-1. The results suggest an excellent compatibility of the very small and hydrophilic fluorescent probe Dbo with solid-phase peptide synthesis and the investigated proteases. For all 14 peptides the fluorescence lifetimes before and after enzymatic cleavage were measured and Nano-TRF measurements were performed in 384-well microplates. The fluorescence lifetimes of the different peptides provide the basis for the rational design of Dbo-based fluorescent substrates for protease assays. Measurements in Nano-TRF mode revealed, in addition to efficient suppression of background fluorescence, an increased differentiation between cleaved and uncleaved substrate. The Dbo-based assays can be adapted for high-throughput screening.

  1. Refractive index effects on the oscillator strength and radiative decay rate of 2,3-diazabicyclo[2.2.2]oct-2-ene.

    Mohanty, Jyotirmayee; Nau, Werner M

    2004-01-01

    The photophysical properties of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) were determined in 15 solvents, two supramolecular hosts (cucurbit[7]uril and beta-cyclodextrin) as well as in the gas phase. The oscillator strength and radiative decay rate of DBO as a function of refractive index i.e. polarizability have been analyzed. The oscillator strength increases by a factor of 10 upon going from the gas phase to the most polarizable carbon disulfide, while the corresponding radiative decay rates increase by a factor of 40. There is a good empirical correlation between the oscillator strength of the weakly allowed n,pi* transition of DBO and the reciprocal bulk polarizability, which can be employed to assess the polarizability of unknown microheterogeneous environments. A satisfactory correlation between the radiative decay rate and the square of the refractive index is also found, as previously documented for chromophores with allowed transitions. However, the correlation improves significantly when the oscillator strength is included in the correlation, which demonstrates the importance of this factor in the Strickler-Berg equation for chromophores with forbidden or weakly allowed transitions, for which the oscillator strength may be strongly solvent dependent. The radiative decay rate of DBO in two supramolecular assemblies has been determined, confirming the very low polarizability inside the cucurbituril cavity, in between perfluorohexane and the gas phase. The fluorescence quantum yield of DBO in the gas phase has been remeasured (5.1 +/- 0.5%) and was found to fall one full order of magnitude below a previously reported value.

  2. Aasta Betoonehitis 2003 - elamu mere kaldal / Enno Rebane

    Rebane, Enno, 1964-

    2004-01-01

    2003. a. parim betoonehitis - arhitekt Emil Urbeli kavandatud eramu (projekteerija TA Konsult OÜ, betoonitööde teostaja Mapri Projekt OÜ). Eriauhinna arhitektuurse lahenduse eest sai Siiri Vallneri, Hanno Grossschmidti ja Tomomi Hayashi kavandatud Lasnamäe spordihoone (projekteerija TA Konsult OÜ, ehitasid Eesti Ehitus OÜ, AS E-Betoonelement - ka betoonisegu tarnija) ja betoonitehnoloogia eest AS E-Betoonelement Ekseko seafarmi sõnnikuhoidla eest Viljandimaal. IV betoonipäevast

  3. Tallinnas möllas 2208 tantsijat / Eveli Rebane

    Rebane, Eveli

    2007-01-01

    Kalevi spordihallis 14.-15. aprillil toimunud rahvusvahelised tantsuvõistlused "Estonian Open Cup" ja "Baltic Cup". Võistlusi korraldab IDO (International Dance Organisation) Eesti haru. "Baltic Cupi" võitjaks tuli Kuressaare tantsutrupp Semiir

  4. Kas "Hirmu faktor" paneb võistleja surmaohtu? / Selene Rebane

    Rebane, Selene

    2004-01-01

    Rahvusvaheline teleprojekt, mille võtted toimuvad Lõuna-Aafrikas. Eesti ainus kaskadöör Enar Tarmo hindab USAs tehtud seriaali pealtnäha kõige eluohtlikumaid trikke turvalisuse seisukohalt. Lisaks tutvustus "Tõsieluseriaal "Hirmu faktor""

  5. Eesti Päevaleht korjas kolm pressipreemiat / Mari Rebane

    Rebane, Mari

    2006-01-01

    Eile jagas Eesti Ajalehtede Liit 2005. aasta ajakirjandussaavutuste eest preemiaid. Eesti Päevaleht sai kujundusauhinna esikaane ja uudiskülgede eest ning arvamusloo preemia. Esikülje kujundusauhinna sai "Eesti Päevalehe" peakunstnik Merike Pinn. Parimateks uudisfoto autoriteks tunnistati Andras Kralla "Äripäevast" ja Margus Ansu "Tartu Postimehest", parimateks olemusfoto autoriteks Raul Mee "Äripäevast" ja Sille Annuk "Tartu Postimehest"

  6. Eesti Raudtee kasvatab läbilaskevõimet / Kirti Rebane

    Rebane, Kirti

    2005-01-01

    Eesti Raudtee investeeringutest, kasumist, kaubaveo mahtudest, majandusnäitajatest, mis annavad head eeldused börsileminekuks, mille üheks plussiks oleks ettevõtte avatumaks muutumine. Tabelid: Eesti Raudtee rahavood (mln kr); Majandusnäitajad. Diagrammid: Eesti Raudtee investeeringud (mln kr); Eesti Raudtee töötajate arv

  7. Michael Moore kaevati kohtusse pettuse eest / Mari Rebane

    Rebane, Mari

    2006-01-01

    Dokumentaalfilm "9/11 Fahrenheiti" ("Fahrenheit 9/11") : režissöör Michael Moore : USA 2004. Iraagi sõja invaliidistunud veteran andis režissööri kohtusse teda kujutavate flmikaadrite loata ja tenentsliku kasutamise pärast

  8. Simpsonite film alustas võimsalt / Mari Rebane, Mart Niineste

    Rebane, Mari

    2007-01-01

    Matt Groeningi loodud tegelaskujudega täispikk animafilm "Simpsonite film" ("The Simpsons Movie") : režissöör David Silverman : Ameerika Ühendriigid 2007. Eestis käis avanädalavahetusel seda vaatamas 13 698 inimest

  9. Krest Alfonsa Rebane / Toomas Virkus ; interv. Maksim Rogalski

    Virkus, Toomas

    1999-01-01

    Saksa sõjaväe Eesti Julgestusgrupi 181 ülema, esimese eestlasest Rüütliristi kavaleri kolonel Alfons Rebase (1908-1976) põrm tuuakse kodumaale ja maetakse 26. juunil Metsakalmistule. Intervjuu A. Rebase ristipoja Toomas Virkusega

  10. New generation in Estonian animation / Mari-Liis Rebane

    Rebane, Mari-Liis, 1988-

    2010-01-01

    Eesti animafilmide loojate uuest põlvkonnast, animafilmide tegemise võimalustest, uute animafilmide tasemest. Martinus Daane Klemeti animafilmidest "Furry Flurry" (2006) ja "Light My Fire" (2007) ning joonisfilmist "Õhus" (Eesti Joonisfilm, 2009, kunstnik Gerda Märtens)

  11. Plaadid / Mari Rebane, Heidi Purga, Tiiu Laks...[jt.

    2008-01-01

    Uutest heliplaatidest Sigur Ros "Heim/Hvart", Jay-Z "American Gangster", Bob Marley and The Wailers "Roots, Rock, Remixed", Ghostface killah "The Big doe Rehab", Backstreet Boys "Unbreakable", Matchbox Twenty "Exile on Mainstream", "Just" Hits 6"

  12. Narnia lood pakuvad naudingut just lastele / Mari Rebane

    Rebane, Mari

    2005-01-01

    Walden Media tootis koos Walt Disney Pictures'iga ekraniseeringu C.S. Lewise 1950.a. ilmunud romaanist "Narnia lood : Lõvi, nõid ja riidekapp" (Chronicles of Narnia : The Lion, the Witch and the Wardrobe")

  13. Huvi või sundus - meie valik / Rein Rebane

    Rebane, Rein

    2011-01-01

    Eesti õpilaste tulemused rahvusvaheliste PISA ja TIMSS-i testide põhjal on olnud head. Samadest uuringutest on aga selgunud, et nii Eesti õpilaste kui ka õpetajate rahulolu kooliga on üks madalamaid maailmas

  14. Rakvere Teater alustab veebruaris uue projektiga / Triin Rebane

    Rebane, Triin

    2010-01-01

    Teatriprojektist "Rakvere Teater esitleb", mille raames jõuavad kord kuus lavale kaasaegse teatri tavapäratumad lavastused, sarja idee autor on teatrijuht Joonas Tartu. 1. veebruaril Alissa Šnaideri, Päär Pärensoni, Renzo van Steenbergeni "Tavaj"

  15. Tehases Polymer valmistatakse kummilelude asemel kultuuri / Mari Rebane

    Rebane, Mari

    2005-01-01

    Tallinna Kristiine linnaosas tegutsevast loovinimeste koondumispaigast kultuuritehasest Polymer. Kultuuritehases töötavad maalikunstnik Alice Kask, skulptor Neeme Külm, teatrikunstnik Mae Kivilo, filmikunstnik Mare Raidma. Vaata ka www.kultuuritehas.ee

  16. Suve kauge trummipõrin kutsub festivalidele / Mari Rebane

    Rebane, Mari

    2004-01-01

    Euroopas suvel toimuvatest popmuusika festivalidest Provinssirock, Pori Jazz Festival, Midtfyns Rockfestival, Roskilde Festival, Glastonbury Festival, V Festivals, Rock Am Ring, Pepsi Sziget. Olulisematest festivalidest Eestis

  17. Oskar Lutsu päevikutest / Hilve Rebane

    Rebane, Hilve, 1938-2012

    1997-01-01

    Arvustus: Oskar Lutsu päevikud aastaist 1915-1916 (I) ja 1917-1919 (II). Tartu : Vanemuise Seltsi Kirjastus, 1996. (Litteraria; 7); Luts, Oskar. Viimane päevik (1944-1952). Tartu : Virgela, 1996. (Litteraria; 9)

  18. 1,4a-Dimethyl-6-methyl-ene-5-(5,5,6,6-tetra-cyano-2-methyl-cyclo-hex-2-enylmeth-yl)deca-hydro-naphthalene-1-carboxylic acid: a trans-communic acid derivative.

    Rejouani, Nezha; Auhmani, Aziz; Ait Itto, My Youssef; Benharref, Ahmed; Daran, Jean-Claude

    2008-01-18

    In the search for cancer chemopreventive agents, we have studied the Diels-Alder reaction of trans-communic acid with tetra-cyano-ethyl-ene in the presence of SiO(2) as catalyst. The title cycloadduct, C(26)H(30)N(4)O(2), was obtained in 75% yield. The mol-ecules are arranged in pairs through O-H⋯O hydrogen bonds, forming an R(2) (2)(8) ring motif. Both the fused cyclohexyl rings adopt a chair conformation, whereas the nonfused ring adopts a half-chair conformation.

  19. Villa Draiver / Mihkel Karu ; kommenteerinud Terje Truumaa

    Karu, Mihkel, 1983-

    2009-01-01

    Villa Draiver (160 m2) Kuressaares Kotkapoja tänaval. Arhitekt ja sisearhitekt Terje Truumaa. Ehitaja: AS Kuressaare Ehitus. Valmis: 2008. Valdavas osas laia püstise helebeeži laudisega kaetud monoliitbetoonist hoone on mõeldud väljaüürimiseks golfihuvilistele

  20. Roostetav legomaja / Karen Jagodin ; kommenteerinud Laila Põdra

    Jagodin, Karen, 1982-

    2009-01-01

    Betoonelementidest eramu (267 m²) Tabasalus. Arhitekt Laila Põdra, insener Indrek Laul. Sisekujundus: Laila Põdra koos omanikega. Projekt: 2005-2007, valmis: 2008. Betoon on viimistluspinnaks ka interjööris. Läbivaks tooniks sise- ja välisviimistluses on roostepunane, teiseks põhitooniks on valge. Konkursil "Aasta Betoonehitis 2008" pälvis tellija eripreemia

  1. Karakteriga kodu / Karen Jagodin ; kommenteerinud Enn Rajasaar

    Jagodin, Karen, 1982-

    2009-01-01

    2008. aastal valminud 2-korruseline eramu Mähel. Arhitekt Enn Rajasaar. Sisearhitekt Aet Seire. Välisviimistluses on kombineeritud tumedat tellist ja heledat krohvi. Sisekujundust läbivad värvid punane ja must. Osa mööbliesemeid (raamatukapid, söögitoa laud) valmisid sisearhitekti erilahendusena

  2. Malchiki malchiki! / Ahto Sooaru ; kommenteerinud Antti Parve

    Sooaru, Ahto

    2009-01-01

    Antti Parve fotonäitusest "Malchiki malchiki". Fotosid sõdurpoistest on eksponeeritud erineval viisil Tapa väljaõppekeskuse õppehoones, Tallinna Loomaaias, Ambulartooriumi galeriis Kasepääl ja Vanemuise kontserdimaja fuajees. Fotograaf meenutab ajateenistust Eesti Kaitseväes

  3. Estimación del impacto económico de los museos a través de las nuevas tecnologías de la información: el caso del museo Ene.Térmica

    Vicente COLL-SERRANO

    Full Text Available Cada vez es más necesario poner de relieve el potencial de la cultura como motor del desarrollo económico y su capacidad para generar ingresos y crear empleo. Por este motivo, en este trabajo se evalúa el impacto económico del museo Ene.Térmica sobre el territorio en el que se ubica, Ponferrada (Comunidad de Castilla y León, España. Para lograr este objetivo, la estimación de los distintos tipos de efectos necesarios para determinar el impacto de las actividades económicas vinculas a la existencia de Ene.Térmica se realiza, en base a la metodología de las Tablas Input-Output, mediante la herramienta Impactrimonio, una aplicación implementada sobre una plataforma web. Los resultados obtenidos indican que entre las actividades del museo y los flujos de demanda desplegados por el efecto arrastre de los visitantes se generó, entre los años 2011 y 2012, un incremento de la producción de más de 15 millones de euros, un incremento de las rentas de la población de casi 10 millones de euros y un aumento de la ocupación de 327 empleos.

  4. Kadriorust leiate pargiraamatukogu / Ene Tamsalu

    Tamsalu, Ene

    2009-01-01

    2006. aastal avati Kadrioru Pargi raamatukogu, mille kogu aluseks on soome maastikuarhitektuuri professori Tuula Maria Merivuori pärandatud erialaraamatukogu, kus leiab kirjandust maastiku-, pargi- ja aiaarhitektuurist, linna- ja regionaalplaneerimisest, botaanikast ja aiandusest

  5. LEADER-tegevusest / Ene Sarapuu

    Sarapuu, Ene

    2009-01-01

    Läänemaa LEADER-tegevusgrupi eesmärk on maakonna kui terviku ühtne areng, et kogu Läänemaa oleks vajalike teenustega kaetud ning ettevõtjad julgeks ning suudaks uute teenuste ja toodetega turule tulla

  6. Messiuudised : Maison & Objet / Ene Jakobi

    Jakobi, Ene

    2008-01-01

    Uusi trende kõige suuremalt disainimessilt Maison & Objet Prantsusmaal - Jean-Charles de Castelbajaci joonistatud toolid, Jean-Christophe Bernardi pleksiklaasist tool ja laud, Joseph Licciardi ja Paul Coheni-Philipp Veenendaali etanoolil põlevad kaminad, Philippe Lebru kellad, Vincenzo Antonuccio vaasid ja Anna Siedlecka ning Radek Achramoviczi täispuhutavad valgustid

  7. Armastus esimesest pilgust / Ene Vool

    Vool, Ene, 1948-

    2005-01-01

    Annika Tederi jaapani stiilis aiast kui tähtsast osast eluruumis, mille kujundamisel on abiks olnud Liina Rehepapp. Jaapani aedadest, jaapanlaste suhtumisest aiakunsti ja lisaks artikkel "Eriilmelised ja -otstarbelised jaapani aiad"

  8. Comment on "An unexpected formation of the novel 7-oxa-2-azabicyclo[2.2.1]hept-5-ene skeleton during the reaction of furfurylamine with maleimides and their bioprospection using a zebrafish embryo model" by C. E. Puerto Galvis and V. V. Kouznetsov, Org. Biomol. Chem., 2013, 11, 407.

    Zubkov, F I; Kvyatkovskaya, E A; Nikitina, E V; Amoyaw, P N-A; Kouznetsov, V V; Lazarenko, V A; Khrustalev, V N

    2017-08-02

    It has been proved that the reaction between furfuryl amines and N-R-maleimides leads to the formation of aza-Michael addition products - 3-(furylmethylamino)-N-R-pyrrolidine-2,5-diones, instead of 7-oxa-2-azabicyclo[2.2.1]hept-5-enes, as this journal reported previously.

  9. Synthesis and Evaluation of in Vitro Biological Activity of 4-Substituted Arylpiperazine Derivatives of 1,7,8,9-Tetrachloro-10,10-dimethoxy-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione

    David Collu

    2009-12-01

    Full Text Available A series of twenty arylpiperazine derivatives of 1,7,8,9-tetrachloro-10,10-dimethoxy-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione have been prepared. These derivatives were tested in vitro with the aim of identifying novel lead compounds active against emergent and re-emergent human and cattle infectious diseases (AIDS, hepatitis B and C, tuberculosis, bovine viral diarrhea. In particular, these compounds were evaluated in vitro against representatives of different virus classes, such as a HIV-1 (Retrovirus, a HBV (Hepadnavirus and the single-stranded RNA+ viruses Yellow fever virus (YFV and Bovine viral diarrhea virus (BVDV, both belonging to the Flaviridae. Compounds 2c, 2g and 3d showed a modest activity against CVB-2. The molecular structures of the starting imide 1 and one of propyl-piperazine derivatives, 3b, have been determined by an X-ray crystallography study.

  10. Clinical efficacy of implementing Bio Immune(G)ene MEDicine in the treatment of chronic asthma with the objective of reducing or removing effectively corticosteroid therapy: A novel approach and promising results.

    Glady, Gilbert

    2018-06-01

    Asthma is one of the diseases that demonstrates a wide range of variation in its clinical expression, in addition to an important heterogeneity in the pathophysiological mechanisms present in each case. The ever-increasing knowledge of the molecular signalling routes and the development of the Bio Immune(G)ene Medicine [BI(G)MED] therapy in line with this knowledge has revealed a whole novel potential set of self-regulation biological molecules, that may be used to promote the physiological immunogenic self-regulation mechanisms and re-establish the homeostatic balance at a genomic, proteomic and cellular level. The aim of the present study is to demonstrate that the sublingual use of a therapeutic protocol based on BI(G)MED regulatory BIMUREGs in the treatment of chronic asthma may reduce or suppress corticosteroid therapy and avoid its harmful side effects which some patients suffer when using this treatment on a long-term basis. The clinical efficacy of BI(G)MED for chronic asthma was evaluated through a multi-centre study carried out in 2016 implementing a 6-month BI(G)MED treatment protocol for Bronchial Asthma. A total of 61 patients from private medical centres and of European countries including Germany, Austria, France, Belgium and Spain participated. The manuscript describes in detail the clinical efficacy of Bio Immune(G)ene regulatory BI(G)MED treatment protocol that allows the reduction or total removal of the corticosteroid dose in patients with chronic asthma. No adverse reactions were observed. The BI(G)MED regulatory therapy brings novel therapeutic possibilities as an effective and safe treatment of chronic asthma. BI(G)MED was demonstrated to significantly reduce asthma severity when parameter compositions were all analysed by categorical outcomes. Therefore, it is considered a good therapeutic alternative for patients who respond poorly to steroids.

  11. Rhodium-catalyzed [5 + 2 + 1] cycloaddition of ene-vinylcyclopropanes and CO: reaction design, development, application in natural product synthesis, and inspiration for developing new reactions for synthesis of eight-membered carbocycles.

    Wang, Yi; Yu, Zhi-Xiang

    2015-08-18

    Practical syntheses of natural products and their analogues with eight-membered carbocyclic skeletons are important for medicinal and biological investigations. However, methods and strategies to construct the eight-membered carbocycles are limited. Therefore, developing new methods to synthesize the eight-membered carbocycles is highly desired. In this Account, we describe our development of three rhodium-catalyzed cycloadditions for the construction of the eight-membered carbocycles, which have great potential in addressing the challenges in the synthesis of medium-sized ring systems. The first reaction described in this Account is our computationally designed rhodium-catalyzed two-component [5 + 2 + 1] cycloaddition of ene-vinylcyclopropanes (ene-VCPs) and CO for the diastereoselective construction of bi- and tricyclic cyclooctenones. The design of this reaction is based on the hypothesis that the C(sp(3))-C(sp(3)) reductive elimination of the eight-membered rhodacycle intermediate generated from the rhodium-catalyzed cyclopropane cleavage and alkene insertion, giving Wender's [5 + 2] cycloadduct, is not easy. Under CO atmosphere, CO insertion may occur rapidly, converting the eight-membered rhodacycle into a nine-membered rhodacycle, which then undergoes an easy C(sp(2))-C(sp(3)) reductive elimination process and furnishes the [5 + 2 + 1] product. This hypothesis was supported by our preliminary DFT studies and also served as inspiration for the development of two [7 + 1] cycloadditions: the [7 + 1] cycloaddition of buta-1,3-dienylcyclopropanes (BDCPs) and CO for the construction of cyclooctadienones, and the benzo/[7 + 1] cycloaddition of cyclopropyl-benzocyclobutenes (CP-BCBs) and CO to synthesize the benzocyclooctenones. The efficiency of these rhodium-catalyzed cycloadditions can be revealed by the application in natural product synthesis. Two eight-membered ring-containing natural products, (±)-asterisca-3(15),6-diene and (+)-asteriscanolide, have been

  12. N-O chemistry for antibiotics: discovery of N-alkyl-N-(pyridin-2-yl)hydroxylamine scaffolds as selective antibacterial agents using nitroso Diels-Alder and ene chemistry.

    Wencewicz, Timothy A; Yang, Baiyuan; Rudloff, James R; Oliver, Allen G; Miller, Marvin J

    2011-10-13

    The discovery, syntheses, and structure-activity relationships (SAR) of a new family of heterocyclic antibacterial compounds based on N-alkyl-N-(pyridin-2-yl)hydroxylamine scaffolds are described. A structurally diverse library of ∼100 heterocyclic molecules generated from Lewis acid-mediated nucleophilic ring-opening reactions with nitroso Diels-Alder cycloadducts and nitroso ene reactions with substituted alkenes was evaluated in whole cell antibacterial assays. Compounds containing the N-alkyl-N-(pyridin-2-yl)hydroxylamine structure demonstrated selective and potent antibacterial activity against the Gram-positive bacterium Micrococcus luteus ATCC 10240 (MIC(90) = 2.0 μM or 0.41 μg/mL) and moderate activity against other Gram-positive strains including antibiotic resistant strains of Staphylococcus aureus (MRSA) and Enterococcus faecalis (VRE). A new synthetic route to the active core was developed using palladium-catalyzed Buchwald-Hartwig amination reactions of N-alkyl-O-(4-methoxybenzyl)hydroxylamines with 2-halo-pyridines that facilitated SAR studies and revealed the simplest active structural fragment. This work shows the value of using a combination of diversity-oriented synthesis (DOS) and parallel synthesis for identifying new antibacterial scaffolds.

  13. Zinc(II PVC-based membrane sensor based on 5,6-benzo-4,7,13,16,21,24- hexaoxa-1,10-diazabicyclo[8,8,8]hexacos-5-ene

    Zamani Hassan Ali

    2006-01-01

    Full Text Available The 5,6-benzo-4,7,13,16,21,24-hexaoxa-1,10-diazabicyclo[8,8,8]hexacos-5-ene (BHDE was used as an excellent ionophore in construction of a Zn(II PVC-based membrane sensor. The best performance was obtained with a membrane composition of 30% poly(vinyl chloride, 64.5% nitrobenzen (NB, 2.5% BHDE and 3% sodium tetraphenylborate (NaTPB. This sensor shows very good selectivity and sensitivity towards zinc ion over a wide variety of cations, including alkali, alkaline earth, transition and heavy metal ions. The sensor revealed a great enhancement in selectivity coefficients for zinc ions, in comparison to the previously reported zinc sensors. The proposed sensor exhibits a Nernstian behavior (with slope of 29.1 ? 0.4 mV per decade over a wide concentration range (1.0 10-6-1.0 10-1 mol L-1 with a detection limit of 6.3 x10-7 mol L-1 (41.2 ng mL-1. It shows relatively fast response time, in the whole concentration range (< 10s, and can be used for at least 10 weeks in a pH range of 2.8-7.3. The proposed sensor was successfully used in direct determination of zinc ions in wastewater of industrial zinc electroplating companies, and also as an indicator electrode in titration with EDTA.

  14. New optically active and thermally stable poly(amide-imide)s containing N,N'-(Bicyclo[2,2,2]oct-7-ene-2,3,5,6-tetracarboxylic)-bis-L-alanine and aromatic diamines: synthesis and characterization

    Faghihi, Khalil; Absalar, Morteza; Hajibeygi, Mohsen [Arak University (Iran, Islamic Republic of). Faculty of Science. Organic Polymer Chemistry Research Lab.

    2009-07-01

    Five new optically active poly(amide-imide)s (PAIs) 6a-e were prepared by direct polycondensation reaction of the newly synthesized N,N'-(bicyclo[2,2,2]oct-7-ene-2,3,5,6-tetra carboxylic)-bis-L-alanine 4 with various aromatic diamines 5a-e using polar aprotic solvents such as N-methyl-2-pyrrolidone (NMP). In this technique triphenyl phosphite (TPP) and pyridine were used as condensing agents to form poly(amide-imide)s through the N-phosphonium salts of pyridine. All of the polymers were obtained in quantitative yields with inherent viscosities between 0.29-0.46 dL g{sup -1} and were highly soluble in polar aprotic solvents such as N,N-dimethyl acetamide (DMAc), N,N-dimethyl formamide (DMF), dimethyl sulfoxide (DMSO), N-methyl- 2-pyrrolidone (NMP) and solvents such as sulfuric acid. They were fully characterized by means of {sup 1}H NMR, FTIR spectroscopy, elemental analyses, inherent viscosity, solubility test, specific rotation and thermal properties of these polymers were investigated using thermogravimetric analysis techniques (TGA and DTG). (author)

  15. New optically active and thermally stable poly(amide-imide)s containing N,N'-(Bicyclo[2,2,2]oct-7-ene-2,3,5,6-tetracarboxylic)-bis-L-alanine and aromatic diamines: synthesis and characterization

    Faghihi, Khalil; Absalar, Morteza; Hajibeygi, Mohsen

    2009-01-01

    Five new optically active poly(amide-imide)s (PAIs) 6a-e were prepared by direct polycondensation reaction of the newly synthesized N,N'-(bicyclo[2,2,2]oct-7-ene-2,3,5,6-tetra carboxylic)-bis-L-alanine 4 with various aromatic diamines 5a-e using polar aprotic solvents such as N-methyl-2-pyrrolidone (NMP). In this technique triphenyl phosphite (TPP) and pyridine were used as condensing agents to form poly(amide-imide)s through the N-phosphonium salts of pyridine. All of the polymers were obtained in quantitative yields with inherent viscosities between 0.29-0.46 dL g -1 and were highly soluble in polar aprotic solvents such as N,N-dimethyl acetamide (DMAc), N,N-dimethyl formamide (DMF), dimethyl sulfoxide (DMSO), N-methyl- 2-pyrrolidone (NMP) and solvents such as sulfuric acid. They were fully characterized by means of 1 H NMR, FTIR spectroscopy, elemental analyses, inherent viscosity, solubility test, specific rotation and thermal properties of these polymers were investigated using thermogravimetric analysis techniques (TGA and DTG). (author)

  16. Ring opening of 2-aza-3-borabicyclo[2.2.0]hex-5-ene, the Dewar form of 1,2-dihydro-1,2-azaborine: stepwise versus concerted mechanisms

    Holger F. Bettinger

    2013-04-01

    Full Text Available The ring opening of the Dewar form of 1,2-dihydro-1,2-azaborine, 2-aza-3-borabicyclo[2.2.0]hex-5-ene (3 is investigated by theoretical methods by using multiconfiguration SCF (CASSCF and coupled cluster theory [CCSD(T] with basis sets up to polarised quadruple-zeta quality. The title compound was previously reported to form photochemically in cryogenic noble gas matrices from 1,2-dihydro-1,2-azaborine (4. Four reaction paths for the thermal ring opening of 3 to 4 could be identified. These are the conventional disrotatory and conrotatory electrocyclic ring-opening pathways where the BN unit is only a bystander. Two more favourable paths are stepwise and involve 1,3-boron–carbon interactions. The lowest energy barrier for the isomerisation reaction, 22 kcal mol−1, should be high enough for an experimental observation in solution. However, in solution the dimerisation of 3 is computed to have a very low barrier (3 kcal mol−1, and thus 3 is expected to be a short-lived reactive intermediate.

  17. The traditional medicine Spilanthes acmella, and the alkylamides spilanthol and undeca-2E-ene-8,10-diynoic acid isobutylamide, demonstrate in vitro and in vivo anti-malarial activity

    Spelman, Kevin; Depoix, Delphine; McCray, Megan; Mouray, Elisabeth; Grellier, Philippe

    2010-01-01

    Spilanthes spp. are used as traditional herbal medicines in Africa and India to treat malaria. Yet, to date, there is no data on active constituents or most effective extraction methods for this indication. The isolated alkylamides, spilanthol and undeca-2E-ene-8,10-diynoic acid isobutylamide, found in S. acmella Murr., were shown to have IC50s of 16.5 μg/mL and 41.4 μg/mL on Plasmodium falciparum strain PFB and IC50s of 5.8 μg/mL and 16.3 μg/mL for the chloroquine resistant P. falciparum K1 strain, respectively. Further investigations revealed that at relatively low concentrations, spilanthol and the water extract of S. acmella reduced the parasitemia 59% and 53% in mice infected with P. yoelii yoelii 17XNL at 5 mg/kg and 50 mg/kg, respectively. Unexpectedly, the 95% ethanol extract of S. acmella was less effective (36% reduction in parasitemia) at 50 mg/kg. These results provide the first evidence supporting S. acmella against malaria and demonstrating active constituents in S. acmella against P. falciparum. PMID:22692989

  18. Kohustus kannatada, et näha ja mõista. Ene Mihkelsoni ja Ingeborg Bachmanni kirjanikunägemus. The Writer’s Duty to Suffer in Order to See and Understand: The Literary Vision of Ene Mihkelson and Ingeborg Bachmann

    Aija Sakova

    2012-04-01

    Full Text Available In an interview from 1971 the Austrian poet and author Ingeborg Bachmann (b 1923 said that there are phenomena that science and scientific language cannot explain. According to her these are the phenomena that belong to the realm of writers and literature. In the same year Ene Mihkelson (b 1946, who had not yet published a single book of poetry or a novel because of censorship, pondered on the role of the author within society: “The author digs under the surface and the author’s responsibility to society lies in his/her persistence, in his/her duty to suffer, to endure stress, which the people in the midst of their busy, daily lives are unable to fully grasp.” Responsibility to society and the duty to suffer and explore the deepest layers below the surface are common to both Mihkelson and Bachmann. Both writers were born and grew up in the shadow of war, violence and totalitarianism. Mihkelson was brought up in a guerrilla family in Soviet Estonia; Bachmann spent her childhood years growing up in the Nationalist-Socialist Austria and in her youth she witnessed the Second World War and its catastrophic consequences. So both of them understand that as writers they cannot overlook the events that they had, either directly or indirectly, witnessed. In an interview from 2009 Mihkelson said that the fact that she remained alive while many did not, that she was not deported to Siberia although it could have happened, has obligated her to write and reflect on what had happened. No consensus has been reached in Europe to condemn Communism as a crime against humanity, but for Estonians Communism and the 50 years of Soviet regime signify a lengthy experience of a totalitarian regime and, in spite of a possible opposition from German-speaking cultures, Communism very often equals Nazism in Estonia. According to Mihkelson, in order to understand and reflect this experience it is not sufficient to rely only on the archives, biographies and books of

  19. Androgen and Progesterone Receptors Are Targets for Bisphenol A (BPA, 4-Methyl-2,4-bis-(P-HydroxyphenylPent-1-Ene--A Potent Metabolite of BPA, and 4-Tert-Octylphenol: A Computational Insight.

    Mohd Rehan

    Full Text Available Exposure to toxic industrial chemicals that have capacity to disrupt the endocrine system, also known as endocrine disrupting chemicals (EDCs, has been increasingly associated with reproductive problems in human population. Bisphenol A (BPA; 4,4'-(propane-2,2-diyldiphenol and 4-tert-octylphenol (OP; 4-(1,1,3,3-tetramethylbutylphenol are among the most common environmental contaminants possessing endocrine disruption properties and are present in plastics, epoxy resins, detergents and other commercial products of common personal and industrial use. A metabolite of BPA, 4-Methyl-2,4-bis(4-hydroxyphenylpent-1-ene (MBP is about 1000 times more biologically active compared to BPA. Epidemiological, clinical, and experimental studies have shown association of BPA and OP with adverse effects on male and female reproductive system in human and animals. The endocrine disruption activity can occur through multiple pathways including binding to steroid receptors. Androgen receptor (AR and progesterone receptor (PR are critical for reproductive tract growth and function. Structural binding characterization of BPA, MBP, and OP with AR and PR using molecular docking simulation approaches revealed novel interactions of BPA with PR, and MBP and OP with AR and PR. For BPA, MBP, and OP, five AR interacting residues Leu-701, Leu-704, Asn-705, Met-742, and Phe-764 overlapped with those of native AR ligand testosterone, and four PR interacting residues Leu-715, Leu-718, Met-756, and Met-759 overlapped with those of PR co-complex ligand, norethindrone. For both the receptors the binding strength of MBP was maximum among the three compounds. Thus, these compounds have the potential to block or interfere in the binding of the endogenous native AR and PR ligands and, hence, resulting in dysfunction. The knowledge of the key interactions and the important amino-acid residues also allows better prediction of potential of xenobiotic molecules for disrupting AR- and PR

  20. Situación de riesgo y salud de los adolescentes en el valle de los ríos Apurímac, Ene y Mantaro en Perú

    Fabiola Yeckting Vilela

    Full Text Available Se presenta el diagnóstico de las condiciones de vida de los adolescentes varones y mujeres en la zona del valle de los ríos Apurímac, Ene y Mantaro (VRAEM, quienes atraviesan situaciones de riesgo y vulnerabilidad social y sexual debido a los altos niveles de producción de la hoja de coca y el contexto del narcotráfico, que crean la ilusión del rápido ascenso social. A partir de ello, es necesario preguntarse ¿cuáles son las condiciones de vida y situaciones de riesgo de los adolescentes en el VRAEM? y ¿cuáles son las alternativas para una mejora de su situación desde el acceso a la educación y los programas de atención de su salud? Esta situación de riesgo es el resultado de las relaciones desiguales de género, violencia sexual, deserción escolar, embarazo adolescente, consumo de alcohol y drogas, así como de la falta de oportunidades como consecuencia de la participación en la economía de la coca y el narcotráfico entre los adolescentes en el VRAEM. Finalmente, se presentan los resultados de la atención de profesionales de los centros de salud para favorecer la consejería en salud sexual y reproductiva y el acceso a los servicios de salud del Programa Vida Adolescente, como oportunidad de vincular los contenidos del currículo de educación y las metas de cumplimiento de este sector, visibilizando la necesidad de un enfoque de interculturalidad e igualdad de género en el acceso a la salud y la educación de los adolescentes.

  1. Effect of tibolone and its principal metabolites (3α- and 3β-hydroxy, 3α-sulfate, and 4-ene derivatives) on estrone sulfatase activity in normal and cancerous human breast tissue.

    Chetrite, Gérard S; Cortes-Prieto, Joaquin; Pasqualini, Jorge R

    2011-12-01

    Tibolone (Org-OD14) is the active substance of Livial®, a synthetic steroid with the structure 7α,17α-17-hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3-one, possessing weak tissue-specific estrogenic, progestogenic, and androgenic properties, used to treat menopausal complaints. After oral administration, tibolone is extensively metabolized into the 3α-(Org-4904) and 3β-(Org-30126) hydroxy derivatives with estrogenic properties, its 4-ene (Org-OM38) isomer with progestogenic/androgenic activities, and the 3α-sulfate (Org-34322) derivative, a major biologically inactive circulating form. We compared the dose response of tibolone and its metabolites on estrone sulfatase activity [conversion of estrone sulfate (E1S) to estrone (E1)] in normal and cancerous human breast tissues. Tissue minces were incubated with physiological concentrations of [3H]-E1S (5×10-9M) alone or in the presence of tibolone and its metabolites (concentration range: 5×10-7to 5×10-5M) for 4 h. Tritiated E1, estradiol (E2), and E1S were separated and evaluated quantitatively by thin-layer chromatography. The sulfatase activity was significantly higher in cancerous breast but strongly inhibited by tibolone and the different metabolites, whereas 3α- and 3β-hydroxy derivatives were the most potent inhibitors. This very significant inhibitory effect of tibolone and its principal metabolites on the enzyme involved in E2biosynthesis in the human breast provides interesting perspectives to study the biological responses of these compounds in trials with breast cancer patients.

  2. Crystal structures of three anhydrous salts of the Lewis base 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU with the ring-substituted benzoic acid analogues 4-aminobenzoic acid, 3,5-dinitrobenzoic acid and 3,5-dinitrosalicylic acid

    Graham Smith

    2016-03-01

    Full Text Available The anhydrous salts of the Lewis base 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU with 4-aminobenzoic acid [1-aza-8-azoniabicyclo[5.4.0]undec-7-ene 4-aminobenzoate, C9H17N2+·C7H6NO2− (I], 3,5-dinitrobenzoic acid [1-aza-8-azoniabicyclo[5.4.0]undec-7-ene 3,5-dinitrobenzoate, C9H17N2+·C7H3N2O6−, (II] and 3,5-dinitrosalicylic acid (DNSA [1-aza-8-azoniabicyclo[5.4.0]undec-7-ene 2-hydroxy-3,5-dinitrobenzoate, C9H17N2+·C7H3N2O7−, (III] have been determined and their hydrogen-bonded structures are described. In both (II and (III, the DBU cations have a common disorder in three of the C atoms of the six-membered ring moieties [site-occupancy factors (SOF = 0.735 (3/0.265 (3 and 0.686 (4/0.314 (4, respectively], while in (III, there is additional rotational disorder in the DNSA anion, giving two sites (SOF = 0.72/0.28, values fixed for the phenol group. In the crystals of (I and (III, the cation–anion pairs are linked through a primary N—H...Ocarboxyl hydrogen bond [2.665 (2 and 2.869 (3 Å, respectively]. In (II, the ion pairs are linked through an asymmetric three-centre R12(4, N—H...O,O′ chelate association. In (I, structure extension is through amine N—H...Ocarboxyl hydrogen bonds between the PABA anions, giving a three-dimensional structure. The crystal structures of (II and (III are very similar, the cation–anion pairs being associated only through weak C—H...O hydrogen bonds, giving in both overall two-dimensional layered structures lying parallel to (001. No π–π ring associations are present in any of the structures.

  3. 7-{[2-(4-Hydroxyphenylmethylidene]amino}-1,3-thiazol-4-yl-2-(methoxyiminoacetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-ylsulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid

    Ghulam Fareed

    2012-05-01

    Full Text Available Novel 7-{[2-(4-hydroxyphenylmethylidene]amino}-1,3-thiazol-4-yl-2-(methoxyiminoacetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-ylsulfanyl]methyl}-8-oxo-5-thia-1azabicyclo [4.2.0]oct-2-ene-2-carboxylic acid was prepared by condensation of ceftriaxone disodium (1 with 4-hydroxybenzaldehyde (2 in ethanol under reflux conditions for 3–4 h. The structure of synthesized compound was elucidated using LCMS, 1H-NMR, and CHN techniques.

  4. 6-Oxocyclohex-1-ene-1-carbonyl-coenzyme A hydrolases from obligately anaerobic bacteria: characterization and identification of its gene as a functional marker for aromatic compounds degrading anaerobes.

    Kuntze, Kevin; Shinoda, Yoshifumi; Moutakki, Housna; McInerney, Michael J; Vogt, Carsten; Richnow, Hans-Hermann; Boll, Matthias

    2008-06-01

    In anaerobic bacteria, most aromatic growth substrates are channelled into the benzoyl-coenzyme A (CoA) degradation pathway where the aromatic ring is dearomatized and cleaved into an aliphatic thiol ester. The initial step of this pathway is catalysed by dearomatizing benzoyl-CoA reductases yielding the two electron-reduction product, cyclohexa-1,5-diene-1-carbonyl-CoA, to which water is subsequently added by a hydratase. The next two steps have so far only been studied in facultative anaerobes and comprise the oxidation of the 6-hydroxyl-group to 6-oxocyclohex-1-ene-1-carbonyl-CoA (6-OCH-CoA), the addition of water and hydrolytic ring cleavage yielding 3-hydroxypimelyl-CoA. In this work, two benzoate-induced genes from the obligately anaerobic bacteria, Geobacter metallireducens (bamA(Geo)) and Syntrophus aciditrophicus (bamA(Syn)), were heterologously expressed in Escherichia coli, purified and characterized as 6-OCH-CoA hydrolases. Both enzymes consisted of a single 43 kDa subunit. Some properties of the enzymes are presented and compared with homologues from facultative anaerobes. An alignment of the nucleotide sequences of bamA(Geo) and bamA(Syn) with the corresponding genes from facultative anaerobes identified highly conserved DNA regions, which enabled the discrimination of genes coding for 6-OCH-CoA hydrolases from those coding for related enzymes. A degenerate oligonucleotide primer pair was deduced from conserved regions and applied in polymerase chain reaction reactions. Using these primers, the expected DNA fragment of the 6-OCH-CoA hydrolase genes was specifically amplified from the DNA of nearly all known facultative and obligate anaerobes that use aromatic growth substrates. The only exception was the aromatic compound-degrading Rhodopseudomonas palustris, which uniquely uses a modified benzoyl-CoA degradation pathway. Using the oligonucleotide primers, the expected DNA fragment was also amplified in a toluene-degrading and a m

  5. Modernne kastmaja Nõmmel / Ene Läkk

    Läkk, Ene, 1957-

    1999-01-01

    Projekteerija: arhitektuuribüroo Mark & Tamm. Konstruktiivne osa: inseneribüroo Randväli Karema. Arhitektid Ülar Mark, Kalle Komissarov. Kahekorruseline maja Vabaduse pst. ääres on mahutatud puude vahele kitsale alale. Kommenteerib Ü. Mark.

  6. Professor Pekka Puska loengud / Ene Indermitte

    Indermitte, Ene, 1967-

    2004-01-01

    Soome Rahvatervishoiu Instituudi direktor, Põhja-Karjala projekti juht prof Pekka Puska peab Tartu ülikoolis loengu "The North Karelia Projekt in Finland and lessons for global chronic disease prevention"

  7. Maia Laul / Maia Laul ; interv. Ene Ammer

    Laul, Maia, 1921-2009

    1998-01-01

    Maia Laul eriala omandamisest, õppejõududest. Lõpetas 1949. a. Tallinna Riikliku Tarbekunsti Instituudi. Alar Kotli käealusena "Estonia" teatri taastamisprojekti juures. Peeter Tarvase ja August Volbergiga ENSV paviljponi kujundamas Moskvas VDNHs. Töötamisest ARSis. Sisearhitektuur ja monumentaalkunst (koostöö Eva Jänesega). Esinemistest näitustel "Ruum ja vorm". Ühiskondlike hoonete sisekujundustest. Vanaturu apteek (klaasigraafika Tiit Jürna)

  8. Riik arhitektuuritellijana / Ene Läkk

    Läkk, Ene, 1957-

    2010-01-01

    Näidete varal Riigi Kinnisvara AS-i korraldatud projekteerimise hangetest, mil välja valiti odavaim pakkumine. Valminud Rakvere politseihoonest ning Jõgeva kohtu- ja politseihoonest. Mudelprojekteerimise (BIM) nõudest. Riigihankest kui salastatud protsessist. Sunnist loobuda autoriõigusest. Riigihankega ühendatud arhitektuurikonkursist

  9. Küberjulgeolekule teed rajades / Ene Ergma

    Ergma, Ene, 1944-

    2007-01-01

    Riigikogu esimees analüüsib aprillisündmustega kaasnenud küberrünnakute kui ühe terrorismi erivormi tagamaid, toob välja vajaduse kujundada küberrünnakute suhtes Euroopa Liidus ja NATO-s ühtne poliitika

  10. Juugendit armastav 21. sajandi kodu / Ene Vool

    Vool, Ene, 1948-

    2006-01-01

    Kaunisse ümbrusse ehitatud stiilne maja, mille projekteeris Margit Kõrts. Sisustus, valgustid ja mööbel on juugendstiilis ja Kadri Tarbe-Pärtelpoeg projekteeris sobiva trepivõre ning trafarettmaalingu tegi Ruth Tuvike, kopeerides Alphonse Maria Mucha seinamaalingut. Mirjam Peili kommentaar

  11. Tagasivaade elule ja ajale / Ene Liivik

    Liivik, Ene, 1933-

    2010-01-01

    Artikkel põhineb kahel käsikirjal "Tagasi waade möödunud elule ja ajale. Utškuju-Tarhani küla aja lugu. 50ne aastane juubel" ja "Lahtised lehed", mille autoriks on Helmi Koolmann. Käsikirjas meenutavad Helmi ja tema abikaasa Rein Koolmann Krimmis elatud aastaid

  12. Uus eesti disain / Ene Läkk

    Läkk, Ene, 1957-

    2009-01-01

    2009. a. disainiöö raames toimunud Eesti Disainerite Liidu algatatud konkursi "Eesti disain ja elukeskond 2009" disainikategooria kümne finalisti tööde tutvustus. 1. koha sai moodulrattahoidja "Rohi" (disain: Keha3), 2. koha vurr-tool "Kiirendi" (disain: Jaanus Orgusaar), 3. koha lastemööbel "Smart kid" (disain: Pavel Sidorenko, Heiki Must)

  13. ŽENE U ZNANOSTI: STAKLENI STROP

    PRIJIĆ-SAMARŽIJA, Snježana; AVELINI HOLJEVAC, Ivanka; TURK, Marko

    2009-01-01

    Temeljni cilj članka jest propitivanje postojanja "staklenoga stropa" ili podzastupljenosti žena na rukovodećim položajima u ustanovama znanosti i visokog obrazovanja kakvo je Sveučilište u Rijeci, uključivo i mehanizama koji ga uzrokuju. Prvi dio članka sadrži kratak pregled i analizu empirijskih rezultata istraživanja provedenog na Sveučilištu u Rijeci, koji nedvojbeno upućuju na prisutnost efekta "staklenoga stropa" i, shodno tome, na postojanje prikrivene primarne i s...

  14. Mida lugeja raamatukogult tegelikult ootab / Ene Riet

    Riet, Ene, 1954-

    2011-01-01

    4. teadus- ja erialaraamatukogude päev toimus 21. oktoobril 2011 Eesti Muusika- ja Teatriakadeemias. Teadusraamatukogu aasta teo auhinna pälvis Urmas Sinisalu tulemusliku ja innovaatilise töö eest raamatukogude infosüsteemi ESTER arendamisel. Erialaraamatukogu aasta teo auhinna sai TÜ ajakirjanduse ja kommunikatsiooni instituudi raamatukoguhoidja Maio Vaniko raamatukogundust arendava tegevuse eest

  15. Tohuvabohu kodukujunduses / Ene Läkk

    Läkk, Ene, 1957-

    2000-01-01

    Tänapäeva Eesti kodukujundusest. Illustratsiooniks 90ndate kolm eramut : neomodernistlik Sinine Maja neominimalistliku interjööriga (Kolm Pluss Üks Arhitektid, arhitekt M. Kaasik), modernistlik villa Sumberg - (Urbel & Peil, arhitekt E. Urbel, sisekujundaja T. Mähar), ökosugemetega modernistlik villa Koger (arhitekt V. Sova, sisearhitektid A. Teigar, M. Press). Kommenteerivad Mart Kalm, Toivo Raidmets. Terminite selgitus.

  16. Ametlikke annetusi 2005. aastal / Ene Riet

    Riet, Ene, 1954-

    2005-01-01

    Saksamaa suursaadik Julius Bobinger kinkis 50 saksakeelset "Kalevipoega" Eesti Kultuuriministeeriumile, kes edastas need maakonnaraamatukogudele, teadusraamatukogudele ja Kreutzwaldi muuseumile Võrus

  17. Vaesusriski muutused Eestis / Ene-Margit Tiit

    Tiit, Ene-Margit, 1934-

    2006-01-01

    Seoses Eesti majanduse kiire arenguga tellis sotsiaalministeerium 2005. aastal uue tarbimiskaalude hinnangu, mille aluseks olid leibkonna eelarvehinnangu andmed aastaist 2000-2004 ning hinnati erineva struktuuriga leibkondade tarbimiskulutusi. Diagrammid. Graafikud

  18. Eesti Etnograafia Ring Kanadas / Ene Runge

    Runge, Ene, 1919-1999

    1993-01-01

    Etnograafia Ring looodi 1971.a ja on pidevalt õpetanud käsitööd, pidanud loenguid eesti ja inglise keeles, korraldanud näitusi ja loonud eesti sektsiooni Royal Ontario Museumi ja Canadian National Museumi juurde kultuurivara säilitamiseks. Seltsi 20. aastapäevaks oli välja antud 61 õppekirja, lisaks õpetused ajakirjas "Triinu" ja õppefilmid, fotod ja diapositiivid, abi on antud samasugustele ringidele Rootsis ja Austraalias, ERM-ile saadeti 1991. a üle 200 rahvakultuuri eseme

  19. Cultural Trauma and Life Stories / Ene Kõresaar

    Kõresaar, Ene

    2007-01-01

    Aili Aarelaid-Tarti 15-aastase uuringu tulemused raamatus "Cultural Trauma and Life Stories", Hesinki, Kikimora Publications, 2006. Uuritud on kolme suurt rahvusgruppi 1940-test tingitud trauma kontekstis: eestlased kodumaal, eestlased eksiilis ja venekeelne rahvusgrupp Eestis postsovetlikus diskursuses

  20. Seadusemuudatused, mis teevad elu paremaks / Ene Kaups

    Kaups, Ene, 1963-

    2008-01-01

    2008. aastal jõustuvatest seadusemuudatustest. Ilmunud ka Koit 7. veeb. 2008, lk. 6 ; Lääne Elu 7. veeb. 2008, lk. 2 ; Hiiu Leht 8. veeb. 2008, lk. 2 ; Järva Teataja 9. veeb. 2008, lk. 2 ; Türi Rahvaleht 8. veeb. 2008, lk. 4, pealkiri kujul: Seadusemuudatustest ; Meie Maa 15. veeb. 2008, lk. 2 ; Sakala 15. veeb. 2008, lk. 2, pealkiri kujul: Käesolev aasta toob hulga olulisi muudatusi ; Sõnumitooja 27. veeb. 2008, lk. 2 ; Valgamaalane 26. veeb. 2008, lk. 2

  1. Pantvangide pered loodavad valitsuse pingutustele / Anneli Ammas ; kommenteerinud Alan Fraser

    Ammas, Anneli, 1962-

    2011-01-01

    Liibanonis röövitud eestlaste lähedaste kommentaare pantvangide uue videopöördumise kohta. President Toomas Hendrik Ilves algatas pantvangide toetuseks kollase lindi kandmise kampaania. Vt. ka juhtkiri lk. 2: Lootuse lindid

  2. Keisri madrusest impeeriumi esivedurijuhiks / Lui Pikkov ; kommenteerinud Hans Treimann

    Pikkov, Lui, 1935-2008

    2009-01-01

    Lui Pikkov oma onust Otto Piksarist (Pikkov), kes sündis Raplamaal Saunakülas, oli madruseks Nikolai II jahtlaeval Poljarnaja Zvezda, töötas vedurijuhina Eestis, oli Eesti NSV Ülemnõukogu saadik

  3. Saaremaalt saab heinaseemet igale maitsele / Jana Rand ; kommenteerinud Hindrek Older

    Rand, Jana, 1963-

    2016-01-01

    Saaremaal Laadjala külas tegutsev OÜ Saaremaa Seeme on Eesti suurim heinaseemne kasvataja, aga mitte erakordselt head looduslikud tingimused pole ettevõtte edu taganud, vaid aastakümnetega omandatud kogemused ja terve Sauna pere pühendunud töö. Vestlusest Arli Saunaga

  4. Energia avastuskeskus = Energy discovery center / Margit Aule ; kommenteerinud Kristiina Raid

    Aule, Margit, 1981-

    2015-01-01

    Energia avastuskeskuse (Põhja pst 29/31, Tallinn) interjöörist ja ekspositsiooni kujundusest. Autor Margit Argus (KAOS Arhitektid); ekspositsiooni kujundus Margit Argus, Margit Aule; arhitektid Sander Aas, Margit Aule, Pelle Sten Viiburg (KAOS Arhitektid). Eesti Sisearhitektide Liidu aastapreemia 2014/2015 parima ajaloolise interjööri eest

  5. Linnalood / Andri Ksenofontov ; kommenteerinud R[eet] V[arblane

    Ksenofontov, Andri, 1962-

    2010-01-01

    Erki Kasemetsa näitus "Kohad/Cities Revealed" ja Liina Siibi näitus "Gimme Danger" sarjast "Cityscape" Tallinna Linnagaleriis. Näitus "Jüri Kaarma lugemistuba" Vabaduse Galeriis. Rühmituse Johnson&Johnson näitus "Nothing Left to Save" Draakoni galeriis. Karel Koplimetsa, Sigrid Viiri ja Taaniel Raudsepa kunstiprojekt "OÜ Visible Solutions" Hobusepea galeriis. Inglise kunstniku Pamela June Crooki isikunäitus galeriis Vaal. Peeter Lauritsa fotonäitus "Trickster's Office" ArtDepoo galeriis

  6. Eisma sadamahoone = Eisma port building / Mari Kurismaa ; kommenteerinud Krista Aren

    Kurismaa, Mari, 1956-

    2015-01-01

    Eluruumid Eisma sadamahoones (Eisma küla, Vihula vald, Lääne-Virumaa). Sisekujunduse autorid Mari Kurismaa, Indrek Allmann; arhitekt Indrek Allmann (AB Pluss). Eesti Sisearhitektide Liidu aastapreemia 2014/2015 parima kodu eest. Lühidalt Mari Kurismaast ja Indrek Allmannist

  7. GDA sinu abimees pakendil / Piret Jaaks ; kommenteerinud Elena Burm

    Jaaks, Piret, 1980-

    2010-01-01

    Euroopa Komisjoni kokku kutsutud toitumisteadlaste komisjoni Eurodiet poolt koostatud GDA toitumisjuhist toiduainepakenditel, mis aitab jälgida toote- või joogiportsjoni osatähtsust päevasest soovitatavast kalorite ning olulisemate toitainete kogusest

  8. Kohtuveskid jahvatavad / Kaija Uuskam; kommenteerinud Maario Laas, Ute Wohlrab

    2014-01-01

    Eesti Hobusekasvatajate Seltsi ja Vana-Tori Hobuse Ühingu vahelisest kohtuvaidlusest tori hobuse tõuraamatu pidamise õiguste üle. Veterinaar ja Toiduameti seisukohti antud küsimuses tutvustab Veterinaar- ja Toiduameti põllumajandusloomade aretuse ja turukorralduse osakonna juhataja Kaija Uuskam

  9. Seadusega garanteeritud rahajõgi / Koit Brinkmann ; kommenteerinud Heido Vitsur

    Brinkmann, Koit

    2010-01-01

    Elering prognoosib, et sel aastal maksab tõhusa koostootmise ja taastuvenergia toetusteks ligi miljard krooni. Tuulejaamadest suuremad toetused lähevad koostootmisjaamadele. Tuuleparkide rajaja OÜ Nelja Energia on saanud kahe töös oleva tuulepargi peale kokku 150 mln. krooni puhaskasumit, sellest 24,3 mln. krooni määrati omanikele dividendideks. Lisa: Kiire ja korraliku lobitöö musternäide

  10. Paper Library = Paper Library / Tomomi Hayashi ; kommenteerinud Una Meiberga

    Hayashi, Tomomi, 1971-

    2015-01-01

    Tomomi Hayashi (HG Arhitektuur) paberist väliinstallatsioon Riias toimunud paberobjektide festivalil. Raamatukogu fassaad ümbritseti volditud valge papiga. Lühidalt Tomomi Hayashist ja büroost HG Arhitektuur

  11. Kas usud seda? / Loore Ehrlich ; kommenteerinud Remo Savisaar

    Ehrlich, Loore

    2013-01-01

    Müüdid: Talvituvad herilased kaitsevad pesa raevukalt; Karu tõuseb enne ründamist tagajalgadele; Kõik ämblikud on ohtlikult mürgised; Puuk kukutab end puude-põõsaste okstelt inimesele; Kõrvahark ronib kõrva ja sealt edasi ajju; Rästik jälitab inimest eesmärgiga rünnata; Nahkhiir on verdihkav vampiir; Ilves ründab inimest puuvõrast turja karates; Näljased hundid murravad inimesi; Sosnovski karuputk kõrvetab; Seen mis ussitab on söögi seen

  12. Valge villa / Karen Jagodin ; kommenteerinud Krista Aren, Emil Urbel

    Jagodin, Karen, 1982-

    2009-01-01

    Villa (623 m² + kelder) Merirahu elamurajoonis Tallinnas. Arhitektid: Emil Urbel, Andrus Mark (AB Emil Urbel OÜ). Sisearhitektid: Krista Aren, Mati Veermets. Inseneriosad: AS Meistri Projekt. Haljastaja: Piret Kukk. Projekt: 2005-2008, valmis: 2009. Villa madalamat osa katab murtud pinnaga graniit, kõrgemat valge krohv

  13. Kolmanda aastatuhande piraadid / kommenteerinud Peter Chalk ja Gordan Van Hook

    2009-01-01

    Piraatlusest Somaalia piirkonnas ja rahvusvahelistest dokumentidest piraatluse vastu võitlemiseks 21. sajandil. Kommenteerivad uurimiskeskuse RAND Corporation vanempoliitanalüütik Peter Chalk ja transpordikompanii Maersk Line innovatsiooni ja arenduse vanemdirektor Gordan Van Hook

  14. LHV kinnitab Soome laenuturul kanda / Silvia Kruusmaa ; kommenteerinud Raul Malmstein

    Kruusmaa, Silvia

    2010-01-01

    LHV sai Soome finantsinspektsioonilt loa hakata osutama piiriüleseid teenuseid Soomes, pank sõlmis Luottotalo Fenno Oy-ga laenuportfelli ostulepingu, omandades ligikaudu 12 500 eraisiku laenulepingud

  15. Klaasis on pinget / Reet Varblane ; kommenteerinud Kati Kerstna, Kairi Orgusaar

    Varblane, Reet, 1952-

    2009-01-01

    Klaasi kui (kunsti)materjali kasutamisest, mitmete erialade sümbioosist. Laura Mattioli Rossi, Rosa Barovier Mentasti ja Adriano Berengo kureeritud näitusest "Glass Stress" ("Klaasipinge") tänavusel Veneetsia biennaalil. Eesti klaasikunstist, Kai Koppeli eestvedamisel toimunud Haapsalu klaasipäevadest "Kasuta päeva"

  16. Vahetuspere isa osutus seksuaalseks ahistajaks / Merje Pors ; kommenteerinud Oliver Kontram

    Pors, Merje

    2011-01-01

    Vahetusõpilase ahistamise juhtumist Argentiinas, kus vahetuspere isa kuritarvitas seksuaalselt vahetusõpilast. Vahetusprogrammide kaudu välismaale õppima minejate arvu vähenemisest, mistõttu on programmid sunnitud ümber orienteeruma ja rohkem välisõpilasi Eestisse tooma

  17. Tudengid tulid appi / Kaupo Kala ; kommenteerinud Heikki Zoova

    Kala, Kaupo

    2010-01-01

    Koristustarvikuid ja -vahendeid tootval ettevõttel KH Teh Production OÜ valmisid koostöös Eesti Kunstiakadeemia tootedisaini osakonnaga ettevõtte tootearendusprojekt, disaini juhtimise kava, uus pakendisüsteem, stiiliraamat, arendati uusi tooteid. Töörühma, kuhu kuulusid neli üliõpilast ja kaks firma töötajat, juhtis EKA tootedisaini osakonna juhataja Heikki Zoova

  18. Arhitekti pilguga betoonist / Madis Eek ; kommenteerinud Maritta Koivisto

    Eek, Madis, 1966-

    2011-01-01

    Žürii liige konkursist "Aasta Betoonehitis 2010". Eramu Pirital Vahtramäe tee 9 - peaauhind, arhitekt Andres Lember. Eesti Maanteemuuseumi välialad - eriauhind tervikliku arhitektuurse lahenduse eest: AB Salto, graafilise betooni idee eest: Laika, Belka & Strelka. Tehvandi spordikeskuse suusastaadion - eriauhind betoonitöö eest: OÜ Savekate (arhitekt Raine Karp). Must maja Nõmmel - terviklahenduse ja betoonitöö eriauhind: arhitekt Martin Aunin, Nordecon Betoon OÜ

  19. Eestlased läti kirjanduses / Contra ; kommenteerinud Hannes Korjus

    Contra, pseud., 1974-

    2011-01-01

    Artikkel põhineb tõlkija ja ajakirjaniku Hannes Korjuse uurimustel ja käsitleb Gunars Janovskise, Märt Lapi (alias Mārtiņš Lapas), Augusts Deglavsi, Zigmunds Skujiņši, Auseklise (Miķelis Krogzemis) loomingut

  20. Jutustamine kui kunst / Tuula Hyyrö ; kommenteerinud Meeli Pandis

    Hyyrö, Tuula

    2009-01-01

    Suulised rahvatraditsioonid ei ole tänapäevalgi oma tähtsust minetanud, vaid on muutunud kunstiharuks, mida saab ülikoolis valikainena õppida. Juttude jutustamisest, muinasjuttude rääkimisest. Kommenteerib Eesti Lugemisühingu juhatuse liige Meeli Pandis

  1. Kuressaare 2008. aasta parimad ehitised selgunud / kommenteerinud Hannes Koppel

    2009-01-01

    Parim terviklahendus golfiala (golfiväljaku projekteerija soome arhitekt Lassi Pekka Tilander, klubihoone projekteeris arhitektuuristuudio Siim & Kreis arhitekt Andres Siim). Parim uusehitis eramu Merikotka 45 (projekteerija Ösel Plan arhitekt Terje Truumaa) ja parim renoveeritud ehitis vana pritsumaja (Kuressaare Kommunaalprojekt projekteerija Galina Kanemägi)

  2. Osobnjak na beregu morja - lutshsheje betonnoje strojenije 2003 goda / Enno Rebane

    Rebane, Enno, 1964-

    2004-01-01

    2003. a. parim betoonehitis - arhitekt Emil Urbeli kavandatud eramu (projekteerija TA Konsult OÜ, betoonitööde teostaja Mapri Projekt OÜ). Eriauhinna arhitektuurse lahenduse eest sai Siiri Vallneri, Hanno Grossschmidti ja Tomomi Hayashi kavandatud Lasnamäe spordihoone (projekteerija TA Konsult OÜ, ehitasid Eesti Ehitus OÜ, AS E-Betoonelement - ka betoonisegu tarnija) ja betoonitehnoloogia eest AS E-Betoonelement Ekseko seafarmi sõnnikuhoidla eest Viljandimaal. IV betoonipäevast

  3. Foorumteater pakub võimalust teisiti mõelda / Mari Rebane

    Rebane, Mari

    2005-01-01

    VAT Teatri foorumgrupp ja MTÜ Caritas loovuskooli teatriringi noored etendavad Sõle gümnaasiumis üht osa VAT Teatri foorumgrupi koolivägivalla ennetamise projektist "ValikuVabadus" (projektijuht M.-L. Velberg), mis hõlmab kuut Tallinna kooli. Ka lühidalt foorumteatri ajaloost

  4. VAT-teatris mõtiskletakse allasurutud pingete üle / Mari Rebane

    Rebane, Mari

    2006-01-01

    13. apr. esietendus VAT Teatris Amélie Nothombi "Vaenlase kosmeetika", tõlkija, lavastaja ja muusikaline kujundaja Peeter Raudsepp, kunstnik Hardi Volmer. Tükki mängitakse rahvusraamatukogu teatrisaalis

  5. Tants ei küsi vanust / Ille Grün-Ots, Siiri Rebane

    Grün-Ots, Ille, 1960-2016

    2007-01-01

    Kanal 2 menusaate "Tantsud tähtedega" järellainetuses vesteldakse artiklis seltskonnatantsust Revalia tantsukooli juhataja Merle Klandorfiga, bailatinost Dance Act direktori Georg Kodusaarega, kõhutantsust tantsuõpetaja Diana Otsinguga ja flamenkost Claudia Shevsthenkoga

  6. Eesti teeb koos soomlaste ja hiinlastega kung-fu filmi / Mari Rebane

    Rebane, Mari

    2005-01-01

    Soome ja Hiina mütoloogiat ühendava fantaasiafilmi "Armuvalus sõdalane" (eelarve 39 milj. krooni) tootjad on Soome, Holland, Hiina ja Eesti (3,9 milj. krooni). Kaasa teeb ka Elle Kull, lavastab debütant AJ Annila

  7. Eksperimendid animatsioonis ja liikuvad pildid = Experiments in Animation and Moving Pictures / Mari-Liis Rebane

    Rebane, Mari-Liis, 1988-

    2011-01-01

    Tallinna XV graafikatriennaal "Armastuse, mitte raha pärast" Kumu Kunstimuuseumis. Triennaalil eksponeeritud animafilmidest, autorid Edmunds Jansons, Stacey Steers, Wojciech Bakowski, Urte Budinaite, Martin Arnold)

  8. "Troonide mäng" toob fantaasia usutavalt teleekraanile / Mari Rebane

    Rebane, Mari

    2011-01-01

    USA telekanali HBO telesarjast "Troonide mäng", George R. R. Martini "Jää ja tule laulu" sarja esimese raamatu "Troonide mäng" teleekraniseeringust. Sarja esimene osa esilinastus USA-s 17. aprillil. Osades Sean Bean jt.

  9. Hansapnk pani ilma loata Meri ja Rüütli oma reklaami / Mari Rebane, Sergo Selder

    Rebane, Mari

    2005-01-01

    Kuna Hansapnga kodulaenureklaamis nimeliselt president Merile ega Rüütlile ei viidata ning visuaalis nende õigeid fotosid ei kasutata, ei ole Tarbijakaitseameti avalike suhete osakonna juhataja Kristina Vaksmaa sõnul tegemist seaduserikkumisega. Lisa: Reklaamiseadus. Kommenteerib Tartu Ülikooli ajakirjandusosakonna juhataja Halliki Harro. Vt. samas lühiintervjuud Hansapanga turundusdirektori Toomas Tiiveliga

  10. Hansapank pani ilma loata Meri ja Rüütli oma reklaami / Mari Rebane, Sergo Selder

    Rebane, Mari

    2005-01-01

    Kuna Hansapanga kodulaenureklaamis nimeliselt president Merile ega Rüütlile ei viidata ning visuaalis nende õigeid fotosid ei kasutata, ei ole Tarbijakaitseameti avalike suhete osakonna juhataja Kristina Vaksmaa sõnul tegemist seaduserikkumisega. Lisa: Reklaamiseadus. Kommenteerib Tartu Ülikooli ajakirjandusosakonna juhataja Halliki Harro. Vt. samas lühiintervjuud Hansapanga turundusdirektori Toomas Tiiveliga

  11. Eesti animafilm külvab uusi seemneid / Mari-Liis Rebane

    Rebane, Mari-Liis

    2009-01-01

    PÖFFi alafestivalil Animated Dreams linastunud neljast uuest filmist: Olga ja Priit Pärna "Tuukrid vihmas", Kaspar Jancise "Krokodill", Martinus Daane Klemeti "Õhus" ja Girlin Bassovskaja (Jelena Girlin, Mari-Liis Bassovskaja) "Oranus"

  12. Nora Särak: kõige suurem katsumus on iseenda usaldamine / intervjueerinud Katariina Rebane

    Särak, Nora

    2016-01-01

    Kevadel Balti filmi- ja meediakooli magistriõppe lõpetanud Nora Säraku lõputööna valminud lühidokumentaalfilm "Valguseks/Valguseni/Valgusena" Petseris elavatest eestlastest pälvis Eesti Kultuurkapitali Audiovisuaalse kunsti sihtkapitali aastapreemia ning film valiti aasta dokumentaalfilmiks. Intervjuu Nora Särakuga

  13. Mae Hansen, girl who got herself a life / Mae Rebane ; intervjueerinud Kristina Traks

    Hansen, Mae

    2011-01-01

    Ameerikas ärihariduse omandanud, pärast seda Eestis Sampo Pangas töötanud ja nüüd Taanis Danske Grupis töötav eestlanna oma tööst, töökorralduslikest erinevustest Eestis ja Taanis, eesmärkidest ja eraelust

  14. Uus raamat tõstis Potteri-palaviku haripunkti / Mari Rebane

    Rebane, Mari

    2007-01-01

    Eestis esilinastus 20. juulil Harry Potteri viies film "Harry Potter ja Fööniksi ordu" ("Harry Potter and the Order of the Phoenix"), režissöör David Yates : Ameerika Ühendriigid-Suurbritannia 2007. Alates 21. juulist saab osta seitsmendat ja ühtlasi viimast J. K. Rowlingu Potteri-sarja raamatut "Harry Potter and the Deathly Hallows"

  15. Samal teemal : kas karistus või võimalused? / Epp Rebane

    Rebane, Epp, 1954-

    2003-01-01

    Vastukaja art.: Kala, Mairoos and Veskioja, Andrus. Klassist klassi määruse abil ... // Õpetajate Leht (2003) 30. mai.1996/1997. õa kehtima hakanud HM-i määrus nr 26 13. novembrist lubab klassikursuse kordajaid kas või kõigis ainetes puudulike hinnetega järgmisse klassi üle viia (kolmandaks aastaks samasse klassi jätta ei tohi). Selle tagajärjel suureneb iga aastaga klassikursuse kordajate ja järgmisse klassi üle viidavate õpilaste arv

  16. Koolid saavad tagasi algusaegade väärikuse / Mari Rebane

    Rebane, Mari

    2003-01-01

    Artur Perna projekteeritud Tallinna 21. keskkooli hoone renoveerimisprojekti autor on Raul Järg, sisekujundaja Toomas Korb, lühtrite disainer Tõnis Vellama. Edgar Johan Kuusiku projekteeritud Lenderi tütarlastegümnaasiumi (Tallinna kesklinna vene gümnaasium) renoveerimisprojekti autor on Andres Põime, sisekujundaja Tiiu Truus

  17. Mereröövlid saabusid suvist letargiat maha raputama / Mari Rebane

    Rebane, Mari

    2006-01-01

    Esilinastus Gore Verbinski piraaditriloogia teine film "Kariibi mere piraadid : Surnud mehe aardekirst" : Ameerika Ühendriigid 2006. Lisaks lühendatud artikkel Los Angeles Times 10. juuli Josh Friedman "Piraadid püstitasid kassarekordi" ja katke ajalehele Guardian antud intervjuust Johnny Deppiga "Kapten Jack Sparrow laseb Deppil pingeid maandada"

  18. Potter 3 ja Shrek 2 teevad puhta töö / Mari Rebane

    Rebane, Mari

    2004-01-01

    J.K. Rowling'u Harry Potteri lugude kolmas film "Harry Potter ja Azkabani vang" ("Harry Potter and the Prisoner of Azkaban") : režissöör Alfonso Cuaron ja animafilm "Shrek 2" on suure kassaeduga maailmas võidukäigul ning tulevad ekraanile ka Eestis, animafilm seejuures eesti keelde dubleerituna

  19. Potteri-raamatut esitletakse teemakohaste üritustega / Mari Rebane, Helen Uldrich

    Rebane, Mari

    2005-01-01

    26. nov. korraldavad suuremad raamatukauplused Tallinnas, Tartus ja Pärnus Potteri teemalisi üritusi seoses Joanne Kathleen Rowling'i "Harry Potter ja segavereline prints" ilmumisega eesti keeles (tlk. Krista ja Kaisa Kaer). Vt. ka Postimees, 24. nov., lk. 18, SL Õhtuleht, 24. nov., lk. 14

  20. Sügiskaamose puhul tõttavad appi kolmed moepäevad / Mari Rebane

    Rebane, Mari

    2007-01-01

    4.10.2007 alanud Tallinna moenädal Tallinn Fashion Week Estonia teatri kammersaalis toob vaatajateni kodumaiste moedisainerite loomingut. Moenädala raames toimub Viru keskuses ka sügisene FIBIT ning Montoni kauplustes Tallinnas ja Tartus antakse tasuta stiilinõuandeid

  1. PÖFF-i festivalid pakuvad aina paremat programmi / Margit Rebane

    Rebane, Margit

    2004-01-01

    VIII Pimedate Ööde filmifestivali alafestivalid : tudengifilmifestival Sleepwalkers, laste- ja noortefilmide festival Just Film, animafilmifestival Animated Dreams (korraldajad Katrin Rajasaare, Elen Lotman, Heilika Võsu). Lisa : Kus toimub? Palju maksab?

  2. Lidar - nesbõvshajasja estonskaja "nokia" / Karl Rebane ; interv. Julia Rodina

    Rebane, Karl, 1926-2007

    2006-01-01

    Eesti NSV teadlaste poolt välja töötatud laserseade lidar, seadme ehitamisest, töötamise põhimõttest ja kasutusvaldkonnast. Akadeemik Karl Rebase sõnul ei oleks sellise ulatusega Läänemere saastamist juhtunud, kui Eestil oleks normaalne ökoloogilise kontrolli süsteem. Poliitikute suhtumisest kodumaise teaduse arengusse

  3. Sadama ala planeering = Harbour area master plan / Ivan Sergejev, Helen Rebane, Karina Niinepuu

    Sergejev, Ivan, 1987-

    2010-01-01

    EKA arhitektuuri ja linnaplaneerimise osakonna IV kursuse 2009-2010 õppeaastal erialase projekteerimise raames kavandatud planeeringu eesmärgiks on tihendada Tallinna sadama ala ning arendada sellest välja mitmekesine ja efektiivne linnaruum

  4. Ene-ene-yne Reactions: Activation Strain Analysis and Role of Aromaticity

    Fernandez, I.; Bickelhaupt, F.M.; Cossío, F.P.

    2014-01-01

    The trend in reactivity of the thermal cycloisomerization reactions of 1,3-hexadien-5-ynes, A=B-C=D-E≡F, were explored and analyzed by using density functional theory at the M06-2X/def2-TZVPP level. These reactions proceed through formally aromatic transition states to form a bent-allene

  5. Martin Veinmann : eks televaataja tahab seebisarjas näha õnnelikku armastust / Martin Veinmann ; interv. Eveli Rebane

    Veinmann, Martin

    2008-01-01

    TV3 draamaseriaali "Kodu keset linna" hooaja lõpp. Seriaalis üht peategelast Hannest kehastav Martin Veinmann endast ja oma rollitegelase suhetest. Lisaks "Hooaeg lõpeb lapserööviga" ja "Olulisemad süzheekäigud"

  6. Tuul väljal / Ene-Reet Soovik

    Soovik, Ene-Reet

    1997-01-01

    Arvustus: Woolf, Virginia. Esseed/ inglise k. tlk. Malle Talvet, Jaak Rähesoo. Tallinn : Hortus Litterarum, 1997; Woolf, Virginia. Orlando : elulugu / inglise k. tlk. Riina Jesmin. Tallinn : Perioodika, 1997. (Loomingu Raamatukogu; 31-34)

  7. ŽENE I SPORT U CRNOJ GORI

    Cheryl Cooky; Marko Begović; Don Sabo; Carole Oglesby; Marj Snyder

    2011-01-01

    This paper is part of a larger study that identifies who plays sport in Montenegro, and the factors (family, education, economic, religious, cultural stereotypes, and so on) that contribute to girls and women’s participation in sport or that limit girls and women’s participation in sport. This study is the first evidencebased research assessing the current status of girls and women’s sport participation in Montenegro, at all institutional levels. Using mixed-methodologies (quantitative assess...

  8. Schone Handen: als de ene hand de andere wast

    C.H.J. van Eijck (Casper)

    2010-01-01

    textabstractRede, in verkorte vorm uitgesproken ter gelegenheid van het aanvaarden van het ambt van bijzonder hoogleraar met als leeropdracht Chirurgie met specifieke aandacht voor het pancreas, aan het Erasmus MC, faculteit van de Erasmus Universiteit Rotterdam op 25 juni 2010

  9. Ülikool ja haridus postajastul / Ene Grauberg

    Grauberg, Ene, 1944-

    2006-01-01

    Informatsiooni kesksest rollist postindustriaalses ühiskonnas, ülikooli ja rakenduskõrgkooli teisenenud funktsioonidest, kõrghariduse uutest trendidest, õppejõu ja üliõpilase suhete muutumisest Pransuse filosoofi Jean-Francois Lyotardi interpreteeringuga

  10. ŽENE I SPORT U CRNOJ GORI

    Cheryl Cooky

    2011-08-01

    Full Text Available This paper is part of a larger study that identifies who plays sport in Montenegro, and the factors (family, education, economic, religious, cultural stereotypes, and so on that contribute to girls and women’s participation in sport or that limit girls and women’s participation in sport. This study is the first evidencebased research assessing the current status of girls and women’s sport participation in Montenegro, at all institutional levels. Using mixed-methodologies (quantitative assessment, survey data and qualitative focus group interviews this study will determine the numbers of girls and women participating in sport, as compared to boys and men in similar demographic categories, and to examine why girls and women do or do not participate in sport and what are their experiences in sport. Initial findings from the demographic assessment of sport in Montenegro illustrate overall gender disparities in sport participation in the 7 most popular sports; the majority of athletes, coaches, managers and decision-makers, medical staff, referees and sport delegates were men. We found the greatest gender imbalance in soccer and basketball, which were overwhelmingly male-dominated, and the greatest gender parity in handball and volleyball- and in some cases there were more female participants than male participants in these sports. We also examined overall trends in gender and sport participation across the different geographical regions, which were similar. However, there were differences in the types of sports men and women played in the different regions, which may indicate that some sports were more popular, or accepted, or easier to access for women in the central part of the country while other sports were more popular, or accepted or easier to access for women in the northern and southern regions. The project is a collaborative partnership with US- and Montenegro based scholars, the International Olympic Committee, the Montenegrin Olympic Committee, the United Nations Development Program, the Office for Gender Equality of the Ministry for Human and Minority Right of Montenegro, and NGO Inovativnost. Reflections and insights on multi-institutional partnerships in the study gender and sport participation will be offered.

  11. Eesti sugemetega jaapani aed / Ene Läkk

    Läkk, Ene, 1957-

    1999-01-01

    Ülle Grishakovi kujundatud aed Kose-Lükatil Pirita jõe käärus endise prügimäe kohal. Kahe hektari suurusel alal on esindatud jaapani aed, dekoratiiv-tarbeaed, inglise stiilis vanaema aed. 7 illustratsiooni.

  12. Lapse ülalpidamise hind / Ene-Margit Tiit

    Tiit, Ene-Margit, 1934-

    2005-01-01

    Tutvustav artikkel sotsiaalministeeriumi tellimusel läbiviidud uuringust, mille eesmärgiks oli välja töötada lapse kõikidest vajadustest lähtuv ühtne metoodika lapse ülalpidamiskulude arvutamiseks ühes kuus. Tabelid. Diagrammid. Vt. ka lk. 15-16: Kaplan, Signe. Metoodika kasutamisvõimalusi

  13. 500-tonniste muldseintega elamu / Ene Läkk, Helen Urbanik

    Läkk, Ene, 1957-

    2000-01-01

    Arhitekt Rick Joy projekteeritud arst John Palmeri villa USAs Arizona osariigis, Santa Catalina mäestiku jalamil. Hoone ühes osas asuvad perekonna eluruumid, teine on avatud ruum. Pressitud muldseinad ja liblikatiiva kujulised terasest katusesiilud jäljendavad ümbritseva maastiku vorme. Suuri seina- ja aknapindu katab raamimata klaas.

  14. Otsused andmekandjate kohta kriminaalmenetluses: proportsionaalsusnõudega arvestamine / Eneli Laurits

    Laurits, Eneli

    2016-01-01

    Riigikohtu lahendist nr. 3-1-1-57-12, proportsionaalsuse nõude rakendamisest asitõendi (andmekandja) täieliku hävitamise korral alamaastmete kohtute praktikas. Sisaldab 2013-2015 aastate asjakohast kohtupraktikat

  15. Tööjuhendid loovuse arendajana / Ene Lind

    Lind, Ene

    2001-01-01

    Loovuse arendamine tööõpetuse ja käsitöö tunnis. Katsest Tallinna koolide 2. ja 4. klasside õpilaste seas, milles katsetati kaht töö raskusastme ning kasutatavate materjalide ja töövahendite poolest erinevat tööjuhendit. Katse järel viidi läbi küsitlus, kus lapsed andsid hinnangu ja kommenteerisid tööjuhendi järgi iseseisvalt töötamist tööõpetuse tunnis

  16. Phytochemical Screening and Characterization of Olean-18-ene ...

    http://dx.doi.org/10.4314/star.v4i1.15 · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact AJOL · News. OTHER RESOURCES... for Researchers · for Journals · for Authors · for Policy Makers ...

  17. Den eneste ene - hvordan etniske minoritetsunge i Danmark danner par

    Singla, Rashmi

    Rapporten handler om etniske unges måde at danne par på. Rapporten er baseret på en større empirisk undersøgelse gennemført af forfatteren i 2003 og er desuden inspireret af forfatterens egen ph.d.-afhandling: "Ungdom, etnicitet og psychosocial intervention" (2000, Københavns Universitet). Rappor...

  18. Episteemilise loogika mõningad aspektid / Ene Grauberg

    Grauberg, Ene, 1944-

    2004-01-01

    Episteemiline loogika on modaalse loogika alasüsteemi loogika teooria, mis kasutab episteemilise operaatoreid ...teab,et..., ...eeldab,et.... Tema aineks on neid operaatoreid sisaldavate otsustuste õige organiseerimise reeglid ja tingimused. Varem ilmunud: Metod modelirovanija i nekotorõje filosofskije problemõ istorii i metodologii jestestvoznanija. Tallinn, 1975.

  19. Põllumajandussaaduste turg : [1994-2003 Eestis] / Ene Maadvere

    Maadvere, Ene, 1948-

    2004-01-01

    Ilmunud ka: Agriculture and rural development : overview 2003/2004. - Tallinn, 2004, lk. 124-132. Põllumajandussaaduste ekspordimaht vähenes 2003. a. eelmise aasta sama perioodiga võrreldes 0,4%, importmaht aga suurenes 7%. Tabelid. Diagrammid. Graafikud

  20. Videomuinasjutt algastme eesti keele tundi : miks ka mitte? / Ene Peterson

    Peterson, Ene

    2002-01-01

    Rets. : Tungal, Leelo. Videomuinasjutt "Printsess Mari ja konn Konrad" [Videosalvestis] = A fairytale on video "Princess Mari and frog Konrad". - Tallinn : Elav Teadus, 1993. - 1 videokassett (VHS) (120 min) + 1 raamat (32 lk.)

  1. Põllumajandussaaduste eksport ja import Eestis 1995. aastal / Ene Maadvere

    Maadvere, Ene, 1948-

    1996-01-01

    Tabelid: Kaupade eksport ja import Eestis; Põhiliste kaubagruppide osatähtsuse muutumine toidukaupade ekspordis; Hinnad; Mõnede toidukaupade eksport 1995.a. võrreldes 1994.a.; Imporditud toidukaupade struktuur võrreldes 1995.a.; Nisuhind Chicago börsil. Diagrammid: Liha-piima tootmine, tarbimine, eksport ja tonnides; Põllumajandussaaduste eksport 1995.a. riikide lõikes

  2. Saarlased võitsid karaokevõistluse / Ene Kallas

    Kallas, Ene

    2009-01-01

    15. veebruaril Tallinna restoranis Kännu Kõrts krooniti Annika Väälma ja Iivo Miil Eesti karaokekuningannaks ja -kuningaks, mõlemad saarlased osalevad ka 28. veebruaril Tallinnas Sokos Hotell Viru restoranis Merineitsi karaoke rahvusvahelisel võistulaulmisel "Finbaltic Karaoke King and Queen"

  3. Mentor - mis see veel on? / Ene-Silvia Sarv

    Sarv, Ene-Silvia

    2001-01-01

    Mentori rollist praktikantide, kutseaastat sooritavate ja uute õpetajate juhendajana, klassijuhatajate ja aineõpetajate nõustajana, kontaktisikuna noorte õpetajate ettevalmistamisel ülikoolis. TPÜ magistrantide mentorirühma projektseminaril "Mentori roll lähituleviku Eesti koolis" ja TÜ mentorirühma õppustel olid teoreetilise põhikursuse kõrval arutusel mentorite praktilise rakendamise võimalused. Analüüsi põhjal tuletati mentorluse neli võimalikku stsenaariumi

  4. Puhtus ja kord majas ning mõtetes / Ene Vool

    Vool, Ene, 1948-

    2007-01-01

    Kalle Rõõmuse projekteeritud inimese bioenergiast lähtuvast eramust, kus raudse järjekindlusega kasutati energeetilisest seisukohast ülimalt inimsõbralikke loodusmaterjale - mida vähem materjale, seda vähem väljamõjusid. Sisearhitekt oli Terje Kivist. Kalle Rõõmuse kommentaar

  5. Amphiphilic silicone architectures via anaerobic thiol-ene chemistry.

    Keddie, Daniel J; Grande, John B; Gonzaga, Ferdinand; Brook, Michael A; Dargaville, Tim R

    2011-11-18

    Despite broad application, few silicone-based surfactants of known structure or, therefore, surfactancy have been prepared because of an absence of selective routes and instability of silicones to acid and base. Herein the synthesis of a library of explicit silicone-poly(ethylene glycol) (PEG) materials is reported. Pure silicone fragments were generated by the B(C(6)F(5))(3)-catalyzed condensation of alkoxysilanes and vinyl-functionalized hydrosilanes. The resulting pure products were coupled to thiol-terminated PEG materials using photogenerated radicals under anaerobic conditions.

  6. Hüdra aastasada / Ene-Reet Soovik

    Soovik, Ene-Reet

    1997-01-01

    Arvustus: Galsworthy, John. Peatüki lõpp : Üle jõe / tlk. Jüri ja Liisi Ojamaa. Tallinn : Eesti Raamat, 1997; Amis, Kingsley. qnneseen Jim / tlk. Urve Hanko. Tallinn : Eesti Raadio, 1997; Boyd, William. Sinine pärastlõuna / tlk. Virve Krimm. Tallinn : Varrak, 1997. Briti XX saj. kirjanduse ülevaade

  7. Palkmaja mõisahäärberiks / Ene Pajula

    Pajula, Ene, 1950-

    2003-01-01

    Riguldi (Rickholtzi) mõisa ajaloost, omanikest, klassitsistlikust häärberist, kõrvalhoonetest. 1967. aastast kuulub Riguldi Tallinna 1. internaatkoolile. Vana kuivati on Taubede järeltulijad tagasi ostnud ja suvemajaks ümber ehitanud. Kommentaarid Lääne maakonna arhitektilt Tõnis Padult. 10 ill

  8. Kooli tehnoloogiaõpetus tuleb atraktiivseks muuta / Ene Lind

    Lind, Ene, 1954-

    2010-01-01

    Üleeuroopalisest tehnoloogiaõppe edendamise projektist "Understanding and Providing a Developmental Approach to Technology Education" - UPDATE ("Tehnoloogiaõpetuse arenguvõimaluste mõistmine ning rakendamine"). Jyväskylä Ülikooli juhtimisel tegid koostööd 16 Euroopa haridus- ja teadusasutust, Eestit esindas Tallinna Ülikooli tööõpetuse osakond koos Eesti Tehnoloogiakasvatuse Liiduga

  9. Sotsiaal-majanduslik staatus tervise tausttegurina / Margo Kikas, Ene Lausvee

    Kikas, Margo

    2008-01-01

    Uuringust seoste kohta Eesti inimeste tunnetatud tervise ning sotsiaal-majandusliku ja psühhosotsiaalse seisundi vahel. Uuring tugineb Tallinna Ülikooli sotsiaaltöö eriala üliõpilaste poolt aastatel 2001-2002 tehtud anonüümsel ankeetküsitlusel põhiliselt toimetulekuraskuste, krooniliste haiguste, puudega või riskikäitumisega isikute seas

  10. People in Ida-Virumaa : between two cultures / Ene Must

    Must, Ene

    2002-01-01

    Peamistest probleemidest Ida-Virumaal, Sillamäel ja Narvas. Kohalike elanike seas läbi viidud Eesti sotsioloogide, Eesti integratsioonifondi ja Saar Polli uuringufirma uurimusest, kus uuriti nende sidemeid naaberriikidega, majanduslikku olukorda ning nende võimalikku elukoha muutust seoses majandusliku olukorraga Eestis ja liitumisega EL-iga. Kokkuvõtted uuringu tulemustest. Diagrammid

  11. Ainenõukogu tähelepanekuid / Ene Laanes

    Laanes, Ene

    2003-01-01

    Üleriigiline kehalise kasvatuse ainenõukogu peab vajalikuks juhtida haridusametnike, koolijuhtide ja kooli omanike tähelepanu kehalise kasvatuse ainekava läbiviimisel üles kerkinud probleemidele: meditsiinilisse erigruppi kuuluvate õpilaste hindamine kehalise kasvatuse aines, kehalise kasvatuse tunniks vajalikud harjutuspaigad ja vahendid, nädalatundide arv

  12. Fluoriidid Eesti elanike joogivees / Astrid Saava, Ene Indermitte

    Saava, Astrid, 1938-

    2007-01-01

    Eesti elanike joogivee-uuringust, mis tehti 2004. aastal Eesti Stomatoloogia Seltsi tellimisel. Lisad: Eesti elanike joogivee fluoriidisisalduse kaart. Elanike jaotus tarbitava joogivee fluoriidisisalduse alusel maakonniti

  13. Võrumaa mitmekesisuse võlu / Ere Raag ; intervjueerinud Ene Riet

    Raag, Ere

    2015-01-01

    Võrumaa Keskraamatukogu pearaamatukoguhoidja räägib, kuidas ja miks valis ta oma erialaks raamatukogunduse, kus ja kellena ta on töötanud ning mida on raamatukogundus talle andnud. Arutletakse ka raamatukogunduse ning raamatukoguhoidja tuleviku üle

  14. Preparation of Novel Hydrolyzing Urethane Modified Thiol-Ene Networks

    2011-10-25

    Desmodur® 3600 were obtained from Ciba Specialty Chemicals and Bayer Material Science, respectively. Chloroform and toluene were obtained from Fischer...2,2,3,3,-tetrafluro propyl tris(2-vinyloxy) ethyl orthosilicate. Ethylene glycol vinyl ether was combined with tetraethyl orthosilicate and 2,2,3,3... propyl tris(2-vinyloxy) ethyl orthosilicate was obtained as a viscous liquid in 88% yield determined by NMR and used without further purification

  15. Läänemeri vs Nord Stream / Ene Kaups

    Kaups, Ene, 1963-

    2009-01-01

    Riigikogu võttis vastu avalduse Läänemerre kavandatava gaasijuhtmega seotud keskkonnariskidest, kus avaldatakse muret, et Nord Stream AG poolt algatatud gaasijuhtme projekti rahvusvahelise keskkonnamõju hinnangutes ei ole piisavalt arvestatud kõigi seonduvate keskkonnariskidega

  16. Uus raadiojaam tuleb venekeelne / Rasmus Rekand ; kommenteerinud Peeter Sookruus ja Ilmar Kompus

    Rekand, Rasmus

    2010-01-01

    Tartu raadiosageduse 101,2 MHz ringhäälinguluba anti AS-le Taevaraadio, kes hakkab edastama venekeelset raadioprogrammi. Kommentaarid kultuuriministeeriumi esindajalt Peeter Sookruusilt ja Sky Media juhatajalt Ilmar Kompuselt

  17. Mis motiveerib Eesti, Soome ja Tšehhi õpetajaid? / Ave Abroi ; kommenteerinud Kertu Laanesoo

    Abroi, Ave

    2009-01-01

    Artikkel on ilmunud Ave Abroi Tartu Ülikooli Euroopa Kolledžis 2008. aastal kaitstud magistritöö "Õpetajate motiveerimise võimalused Euroopa Liidus Eesti, Tšehhi ja Soome näitel" põhjal. Kommenteerib Audentese erakooli inglise keele õpetaja Kertu Laanesoo

  18. Viking Line pakub mugavat reisimisvõimalust / kommenteerinud Inno Borodenko, Piret Pääsik

    2009-01-01

    1. juunil 2009 täitus 50 aastat laevakompanii Viking Line asutamisest ja 15 aastat Viking Line tulekust Eestisse. Viking Line Eesti OÜ tegevjuht Inno Borodenko ja turundusjuht Piret Pääsik tutvustavad laevafirma saamislugu, eesmärke ning tegevust.

  19. "IT-planeet" - kontakt tulnukatega TV 3s / Annely Adermann ; kommenteerinud Tarmo Randel

    Adermann, Annely, 1974-

    2011-01-01

    Uuest hariduslikust teleseriaalist "IT-planeet", mille eesmärk on vaatajale selgitada arvutite ja turvalisusega seotud teemasid. Režissöör Margus Paju, stsenarist Rasmus Merivoo. Seriaali näeb TV 3-s alates 16. märtsist

  20. Euroopa päeva pidustused juurviljahelide saatel / Kerttu Kongas ; kommenteerinud Urmas Kruuse

    Kongas, Kerttu

    2009-01-01

    Euroopa päeval, 9. mail esineb Tartu Raekoja platsil omavalmistatud köögiviljainstrumentidel rahvusvahelise tuntusega Juurviljaorkester Viinist (The Vegetable Orchestra ehk Das Erste Wiener Gemüseorchester). Euroopa Liidu teemanädala üritused

  1. Eesti koolid ei jaksa enam Microsoftilt tarkvara osta / Teele Tammeorg ; kommenteerinud Rain Laane

    Tammeorg, Teele

    2013-01-01

    Eesti koolide arvutid on nii vananenud, et ei saa kasutada uuemaid operatsioonisüsteeme, Windowsi operatsioonisüsteem ja MS Office'i kasutamine aga kallineb vähemalt kümme korda. Arvamust avaldab ka Tallinna ülikooli haridustehnoloogia keskuse juht Mart Laanpere

  2. Väärt vara linnas ning maal / Ain Alvela ; kommenteerinud Mart Saa

    Alvela, Ain, 1967-

    2010-01-01

    Uus Maa Kinnisvarabüroo tegevjuhi Mika Sucksdorffi hinnangul on Tallinnas kinnisvara üks arengusuundi Kalamaja-Kopli-Paljassaare piirkond. A&A Kinnisvara tegevjuhi Aivar Villemsoni hinnangul hakkavad kinnisvarahinnad tõusma esmalt pealinna keskmes, Rocca al Mare ja Pirita kandis

  3. Koda = Koda / Ülar Mark, Kariina Kristiina Kaufmann, Kadri Tonto ; kommenteerinud Katrin Koov

    Mark, Ülar, 1968-

    2016-01-01

    Minimalistliku vormiga eramu KODA Tallinnas, Järvekalda tee 33. Autorid Ülar Mark, Taavi Jakobson, Hannes Tamjärv, Kalev Ramjalg, Marek Strandberg. Arhitektid Ülar Mark, Kariina Kristiina Kaufmann, Kadri Tonto, Hannes Praks

  4. Ostukoha valikul pole hind ainus ja tähtsaim argument / Sirje Niitra ; kommenteerinud Tiina Hiob

    Niitra, Sirje, 1948-

    2015-01-01

    Uue kaubakeskuse avamisega sai Viimsi asula keskne ristmik endale kokku viis suurt ostukohta. Artiklis selgub, mille järgi selle kandi inimesed ostukoha valiku teevad. Valiku tegemisel mängivad suurt rolli ka psühholoogilised tegurid, vahel eelistatakse just kõrgemaid hindu, sest olulised on maine ja staatus

  5. Tallinna idee / Andres Alver, Ott Alver, Marten Kaevats ; intervjueerinud Margit Mutso ; kommenteerinud Douglas Gordon

    Alver, Andres, 1953-

    2011-01-01

    17. veebruaril esitleti raamatut "Tallinna idee", mis on koostatud Eesti Kunstiakadeemia 4. kursuse arhitektuuritudengite kursuseprojektide põhjal. Tallinna teemal vestlevad tudengid Ott Alver ja Marten Kaevats ning nende juhendaja professor Andres Alver

  6. Projekt EUth, platvorm OPIN ja noorte e-osalemine / Teo Gregov, Kerstin Franzi ; kommenteerinud Ivo Visak

    Gregov, Teo

    2016-01-01

    Projekti EUth eesmärk on suurendada noorte huvi ja aktiivset osalemist nii kohalikes kui ka Euroopa poliitilistes institutsioonides ja organisatsioonides. Projekti tulemusena valmis veebiplatvorm OPIN (www.opin.me), mis aitab projekte kavandada ja hallata

  7. "Ekspeditsioon Wunderlich" = "Expedition Wunderlich" / Carl-Dag Lige, Hannes Praks ; kommenteerinud Triin Ojari

    Lige, Carl-Dag, 1982-

    2016-01-01

    Näitus "Ekspeditsioon Wunderlich" Eesti Arhitektuurimuuseumis. Autorid Katrin Talvik, Merilin Tee, Sabine Suuster, Martin Saar, Karl Taul, Alden Jõgisuu, Tõnu Lensment, Aadam Kaarma, Cael-Dag Lige, Hannes Praks. Näitus on Eesti Kunstiakadeemia ja Eesti Arhitektuurimuuseumi ühisprojekt

  8. Abikäsi miljardite liigutajatele / Kadri Jakobson ; kommenteerinud Paavo Põld, Juhan Parts

    Jakobson, Kadri, 1970-

    2010-01-01

    Varahaldusettevõtted Limestone Investment Management, Redgate Asset Management ja Avaron Asset Management on saanud EAS-ilt eksporditoetusi kokku 5,4 mln. krooni, kuid pole teada, millele täpselt raha kulub. EAS-i selgitusi

  9. Swiss Property kontor = Offices of Swiss Property / kommenteerinud Tõnis Sõõrumaa

    2015-01-01

    Swiss Property kontoriruumid Tallinnas Rotermanni 8. Sisekujunduse autorid Kätlin Ölluk, Tiina Kesküla, Katy Seppel, Aet Kiivet, Liina Rohtlaan, Marita Mätas, Lilian Esing, Kristin Boginski (Swiss Property); arhitektid Yoko Azukawa, Hanno Grossschmidt, Tomomi Hayashi

  10. Kuldne poolkaar embab Pärnut / Silvia Paluoja ; kommenteerinud Eeri Tammik ja Maia-Liisa Kasvandik

    Paluoja, Silvia, 1956-

    2010-01-01

    Pärnu ja Pärnut ümbritsevate piirkondade võrgustikke siduva teemaplaneeringu koostamisest. Lisatud Pärnumaa Omavalitsuste Liidu esimehe Eeri Tammiku ja Tahkuranna valla planeeringunõuniku Maia-Liisa Kasvandiku kommentaarid

  11. 21. sajandi õpetajast ikka veel tulevikuvaates / Sirje Pärismaa ; kommenteerinud Margit Timakov ja Kristi Mikiver

    Pärismaa, Sirje, 1958-

    2015-01-01

    Maailma parima haridusega riikide viiendal tippkohtumisel Kanadas Banffis jõuti kõnelustega 21. sajandi klassiruumi: arutleti õpetajate liidrirolli, koostöö ja innovatsiooni üle ning küsiti, mida teha teisiti, et ühiskond õpetajat senisest rohkem väärtustaks

  12. Tarmo Kriis: Eesti majandus kukkus tagasi aastasse 2007 / Lemmi Kann ; kommenteerinud Ain Seppik

    Kann, Lemmi

    2009-01-01

    Tööandjate keskliidu juht Tarmo Kriis esitles eelarve kokkuhoiukava tutvustamisel tööandjate prognoosi, mille järgi on Eesti majandus tagasi aastas 2007 ning maksimumtase kulude osas saabki olla sama, mis 2007. aastal

  13. Riigikohus arutleb autode üle / Ranno Tingas, Lemmi Kann ; kommenteerinud Jüri Allikalt

    Tingas, Ranno, 1976-

    2009-01-01

    Riigikohtu lahenditest 3-3-1-93-08, 3-3-1-44-00, Tallinna Ringkonnakohtu lahendist 2-3-143/2002 sõiduautode erisoodustuse küsimuses. Kommenteerib Maksukonsultandi UÜ jurist, Eesti Maksumaksjate Liidu (EML) juhatuse liige Jüri Allikalt. Lisa: Maksuamet: sõidupäevikud ei kao kuhugi / Lemmi Kann (ÄP Online, 05.03.2009) ; MTA pressiteade ; EML teabenõue ; MTA vastus

  14. Rohelise joonega kodu / Piret Veigel ; kommenteerinud Anu Hännikäinen

    Veigel, Piret, 1961-

    2012-01-01

    Perekond Rüüsaki modernselt funktsionaalne kodu pälvis konkursil "Kodu kauniks 2011" stiilseima kodu preemia. Maja projekteeris Andri Kirsima, sisearhitekt oli Pille Tael, kes koostöös skulptor Kalle Pruudeniga projekteerisid ja teostasid eritellimusel valgustid

  15. Ilu võitlus koleduse välja vastu / Rebekka Lotman ; kommenteerinud Mart Anderson

    Lotman, Rebekka, 1978-

    2009-01-01

    Konkursside "25 kauneimat Eesti raamatut" ja "Viis kauneimat Eesti lasteraamatut" võidutööde näitus Eesti Rahvusraamatukogus. Võidutööde valikut kommenteerib žürii esimees Mart Anderson. Loetletud 2008. aasta 25 kaunimat raamatut. Nimekiri: 2008. aasta 25 kauneimat raamatut

  16. Ka suured ettevõtted suudavad kasvada / Koit Brinkmann ; kommenteerinud Mart Brauer, Jaak Kivisild

    Brinkmann, Koit

    2010-01-01

    Gasellide ehk kõige kiiremini kasvanud ettevõtete edetabelit juhtivast Tartu logistikafirmast Transring Tartu OÜ, ettevõtetest Baltic International Trading OÜ, Olerex AS, Viimsi Keevitus AS. Tabel

  17. Uus Ansip on Pentus, uus Savisaar Ratas või Simson / Argo Ideon ; kommenteerinud Andrus Ansip

    Ideon, Argo, 1966-

    2011-01-01

    USA Tallinna saatkonna Wikileaksi kaudu avalikuks saanud dokumentides analüüsitakse Eesti sisepoliitikat ja riigijuhtide tausta. Peaminister Andrus Ansipist. President Toomas Hendrik Ilvese hinnanguid peaministri kohta üheski Postimehe käsutuses olevas USA Tallinna saatkonna ettekandes ei esitata

  18. Taani viib õpilaste testimise Internetti / Jacob Wandall ; intervjueerinud Raivo Juurak ; kommenteerinud Anti Teepere

    Wandall, Jacob

    2009-01-01

    Ülevaade adaptiivtestidest ja nende rakendamise kavadest Taani põhikoolis. Vestlus Taani haridusministeeriumi koolivalitsuse peaspetsialist Jacob Wandalliga, kommenteerib REKK-i üldhariduse õppekavade ja eksamite osakonna peaspetsialist Anti Teepere

  19. Peaprokurör: kaevake kartellide peale! / Kadri Paas ; kommenteerinud Norman Aas ; Indrek, Kaju

    Paas, Kadri, 1982-

    2009-01-01

    Seaduseelnõust, mille kohaselt salajasest kartellileppest esimesena võimudele teatanud ettevõte pääseb vastutasuks karistusest. Kommenteerivad peaprokurör Norman Aas ning Neste Eesti peadirektor Indrek Kaju

  20. Siim Kallas seab Lumani argumendid kahtluse alla / Kadri Paas ; kommenteerinud Norman Aas, Juhan Põldroos

    Paas, Kadri, 1982-

    2009-01-01

    Seaduseelnõust, mille eesmärgiks on tõhustada võitlust kartellidega ja muude raskete konkurentsiõiguse rikkumistega nn leebusprogrammi abil. Kommenteerivad peaprokurör Norman Aas ja Juhan Põldroos

  1. Pagari 1 kortermaja = Apartment building at Pagari 1 / Reio Raudsepp ; kommenteerinud Reet Roos

    Raudsepp, Reio

    2015-01-01

    Pagari 1 kortermaja (Tallinn, vanalinn) renoveerimisest. Hoone arhitekt Hans Schmidt, valmimisaasta 1911. Renoveerimise autorid Reio Raudsepp, Rasmus Tamme, Jaanus Saarepera; projekteerija ARS Projekt

  2. Toetuse saab äpardujalt tagasi nõuda / Kairi Oja ; kommenteerinud Lea Orro

    Oja, Kairi

    2011-01-01

    PRIA peadirektor Jaan Kallas, SA Archimedes struktuuriüksuste juhataja Alice Liblik, Keskkonnainvesteeringute Keskuse kommunikatsioonijuht Kristiina Pennar, SA Innove juhatuse liige Lea Orro ning Kredexi juhataja Andrus Treier eurotoetuste tagasinõudmise põhjustest

  3. Ärikultuur 15 aastat tagasi / Urve Vilk ; kommenteerinud Aku Sorainen

    Vilk, Urve

    2011-01-01

    Krediidipanga juhatuse esimehe Andrus Kluge hinnangul oli ärikeskkond Eestis 15 aastat tagasi mitteformaalsem, naiivsem ja spontaansem kui praegu, kõik tegelesid kõigega. Margus Alviste hinnangul on 15 aastaga muutunud tavad ja kombed, rohkem on variserlikkust, eestlaste ettevõtlikkus on vähenenud

  4. "Riik malelaual" = "Country on a Chessboard" / Tarmo Piirmets ; kommenteerinud Laura Kipper

    Piirmets, Tarmo, 1974-

    2015-01-01

    Eesti Ajaloomuuseumi näitus "Riik malelaual. Saksa okupatsioon Eestis 1941-1944" Maarjamäe suvemõisa tallihoones, kuraator Olev Liivik. 19. sajandist pärit tallihoone renoveerimisest. Autor Tarmo Piirmets (Pink); arhitektid Jaak Huimerind, AB Studio Paralleel

  5. Valjala pastoraadis küpsetatakse piparkooke / Rita Loel ; kommenteerinud Hannes Nelis

    Loel, Rita, 1966-2012

    2009-01-01

    EELK Valjala Martini kogudus ja Valjala vallavalitsus korraldavad kaheksandat aastat esimesel advendipühapäeval kontserdi "Laulud jõulude ootuses", kus kuulutatakse välja jõulurahu ning pakutakse Valjala pastoraadis küpsetatud piparkooke

  6. Õigeksmõistev otsus vallandas publiku tormilise aplausi / Tiiu Põld ; kommenteerinud David Vseviov ; Marju Lauristin

    Põld, Tiiu, 1945-

    2009-01-01

    Harju maakohtu õigeksmõistvast otsusest aprillirahutuste korraldamises süüdistatavate Dmitri Linteri, Maksim Reva, Dimitri Klenski ja Mark Sirõki kohta. Kommenteerivad David Vseviov ja Marju Lauristin

  7. Teaduspargist võrsub eriti agar gasell / Ain Alvela ; kommenteerinud Seren Eilmann

    Alvela, Ain, 1967-

    2010-01-01

    Tallinna tehnoloogiapargi Tehnopol ja Tartu teaduspargi ettevõtlusinkubaatorid pakuvad ettevõtluskeskkonda kiiret arengut taotlevatele ettevõtetele. Tehnopolis on gaselli staatuse saanud 22 firmat, Tartu teaduspargis 13 firmat. AS-ist Proekspert, OÜ-st Interfire. Tabel

  8. Kas minna õppekogunemisele ja lasta kodutalu põhja? / Rein Raudvere ; kommenteerinud Kaul Nurm

    Raudvere, Rein, 1955-

    2011-01-01

    Vajadusest muuta kaitseväeteenistuse seadust, et põllumehi ebasobival ajal kordusõppustele ei kutsutaks. Varem vabastas taluseadus põllumeestest reservväelased õppekogunemistest, kuid 2 aastat tagasi tunnistati vastav säte kehtetuks

  9. Laos ja tootmises piirid paika. Selge markeering tagab korra / Jaana Pikalev ; kommenteerinud OIiver Licht

    Pikalev, Jaana

    2011-01-01

    Inglismaa ekspertide hinnangul peaksid Eesti firmad oluliselt parandama tööohutust ning tootmishooneid ja töötingimusi. Lao- ja tootmispindu tuleks markeerida. Kalevi kommivabriku laokoordinaatori Siim Simsi hinnangul võiksid Eestis olla markeerimisstandardid

  10. Võhiklikuse kokkupõrge : [art.] / Edward Said ; inglise keelest tõlkinud ja kommenteerinud: Udo Uibo

    Said, Edward

    2001-01-01

    Samuel Huntingtoni artiklist "Tsivilisatsioonide kokkupõrge" (Akadeemia, 1995, nr. 6, lk. 1205-1233).Artikkel on ilmunud erinevate pealkirjade all ajalehtedes "Al-Ahram" (11. - 17. okt. 2001) ja "The Nation" (22. okt. 2001)

  11. Kas lähisuguluspaaritus vähendab viljakust? / Marja Hietakorpi ; kommenteerinud Ulrika Tuppits

    Hietakorpi, Marja

    2010-01-01

    Soome teadlaste uuringust inbriidingu mõjust hobuse tiinestuvusele, mille uuringumaterjaliks oli 33 679 soojaverelise traavli ja 32731 soome tõugu hobuse seemendusandmed Soome Hobusekasvatajate Seltsi Hippos registris aastatel 1991-2005

  12. Positiivsust saab õppida / Mare Pork ; intervjueerinud Signe Rummo ; kommenteerinud Toivo Aavik

    Pork, Mare, 1950-

    2014-01-01

    Intervjuu Tallinna Ülikooli psühholoogiaprofessor Mare Porkiga positiivsest psühholoogiast ja raamatust Boniwell, Ilona. Positiivne psühholoogia : tõhusa toimimise põhitõed. Tallinn : Äripäev, 2014.

  13. Kaubavedaja vastutab lasti kilo eest 150 krooniga / Siim Sultson ; kommenteerinud Renee Mahl

    Sultson, Siim

    2010-01-01

    Eestis ja Euroopa Liidus piirdub vedaja vastutus veose eest kindla summaga, ülejäänu jääb kliendi kindlustada. Vääramatu õnnetuse korral ei vastuta vedaja millegi eest. Riigisisese ja rahvusvahelise vastutuse võrdlus

  14. Portreefotograafia Oscarid. Kuidas neid küll jagada? / Annika Haas ; kommenteerinud Birgit Püve

    Haas, Annika, 1974-

    2016-01-01

    Londoni rahvusliku portreegalerii (National Portrait Gallery) poolt 2003. aastal algatatud portreefotokonkursist Taylor Wessing Photographic Portrait Prize (TWPPP). 2015. aasta võidutöö: David Stewart "Viis tüdrukut"

  15. Keemiatööstus maadleb üüratu maksukoormaga / Hallar Meybaum ; kommenteerinud Ruth Oltjer

    Meybaum, Hallar

    2009-01-01

    Eesti keemiatööstuses on palju tehtud tootmisharu efektiivseks ja tootmissõbralikuks muutmiseks. Vaatamata sellele vajab keemiatööstus senisest rohkem finantskapitali, oskuslikku tööjõudu ja tõhusat tootearendust. Diagramm

  16. Kremli org - Venemaa ehitab oma Silicon Valley analoogi / Jaanus Piirsalu ; kommenteerinud Jaanus Piirsalu

    Piirsalu, Jaanus, 1973-

    2010-01-01

    Venemaale kavatsetakse rajada tehnoloogia arendamise ja innovatsiooni piirkond, mille eest vastutab presidendi administratsioni asejuht Vladislav Surkov. Linnakesele on pandud tinglik nimi - Innograd. Diagrammid

  17. Playtechi büroo = Offices of Playtech / Jan Skolimowski, Maie Raud ; kommenteerinud Ivo Lasn

    Skolimowski, Jan, 1977-

    2016-01-01

    IT-arendusettevõtte Playtech Tallinna osakonna bürooruumid Ülemiste City uues hoones Lõõtsa tn. 5. Arhitektid Jan Skolimowski, Maie Raud (KAMP Arhitektid). Logo ja viidagraafika Martin Eelma (Tuumik)

  18. Eesti Tervishoiu Muuseum = Estonian Health Care Museum / Raili Paling, Liis Lindvere, Kadri Kaldam ; kommenteerinud Kadri Liimal

    Paling, Raili

    2016-01-01

    Eesti Tervishoiu Muuseumi (Tallinn, Lai tn. 30) renoveeritud interjöör ja püsiekspositsioon. Autorid Jelena Altmäe, Kadri Kaldam, Andrus Kõresaar, Indrek Mikk, Jaanus Männik, Lea Laidra, Liis Lindvere, Raili Paling; kuraator Ülle Kask

  19. Twilio Eesti büroo = Offices of Twilio Estonia / Katrin Kaevats ; kommenteerinud Ann Koljang

    Kaevats, Katrin, 1980-

    2016-01-01

    Rahvusvahelise ettevõtte Twilio Eesti büroo Tallinnas, Veerenni tn. 24. Sisekujunduse autorid Katrin Kaevats, Jaan Port, Markus Nimik, Neeme Tiimus, Anna Nikland. Büroohoone projekteerisid PIN Arhitektid

  20. "Boob teab" / Kalju Komissarov ja Rait Avestik ; kommenteerinud ja toimetanud Anneli Saro

    Komissarov, Kalju, 1946-2017

    2010-01-01

    Teatriseminar sarjast "Eesti algupärandid Eesti teatris" toimus Tartu Kirjanduse Maja krüptis 28. märtsil 2005, seminari juhtis Anneli Saro. Urmas Lennuki näidendi kolmest lavastusest: Tallinna Linnateatris (esietendus 28. veebruaril 2004, lavastas Jaanus Rohumaa), Rakvere Teatris (esietendus 10. septembril 2004, lavastas Kalju Komissarov) ja Vikerraadios (esietendus 4. septembril 2004, lavastas Tamur Tohver)

  1. Talutoidu tootjad tahavad varjusurmas "Eesti toidu" programmi ellu äratada / Heli Raamets ; kommenteerinud Karina Loi

    Raamets, Heli, 1975-

    2011-01-01

    Talutootjad leidsid seminaril "Kohalik toit tarbijani 2020 - kuidas?", et nende toodangu paremaks tarbijani jõudmiseks on vaja teha koostööd ning kohaliku toidu strateegia ja tegevuskava oleks vaja kajastada uues maaelu arengukavas

  2. Kapo nuusib moslemiperesid / Kattri Ezzoubi ; intervjueerinud Tiina Jõgeda ; kommenteerinud Andres Kahar

    Ezzoubi, Kattri, 1969-2011

    2010-01-01

    Kaitsepolitsega koostööd teinud araabia keele ja islamimaade kultuuri õpetaja sõnul ei hoia kaitsepolitsei Eestisse abielu kaudu jõudnud moslemitel mitte ainult silma peal, vaid kutsub neid ka vestlusele kaitsepolitseiametisse. Tema hinnangul on kaitsepolitsei huviorbiidis kindlasti need, kellel on olnud pikemaajalisem kokkupuude mõne araabia riigiga

  3. Kaks kuud Kalev SPA-s / kommenteerinud Julia Kurbat, Natalia Nazarenko-Kiivikas, Margit Lipstuhl

    2012-01-01

    Kahe spordiharrastaja Kaur Sau ja Kadri Sõggeli seatud eesmärkidest 2012. aastal ja kehalisest arengust treenides kaks kuud mõnes Tallinna spordiklubis. Treeningutest Kalev Spa Hotel & Water Park'i nimekandvas spordi- ja vabaajakeskuses

  4. Matsalu festival - aina parem / Ingmar Muusikus ; kommenteerinud Ulvar Käärt

    Muusikus, Ingmar, 1971-

    2011-01-01

    Lihulas toimunud 9. Matsalu loodusfilmide festivali fotoprogrammist. Remo Savisaare näitusest "Imelised linnud". Tiit Leito näitusest "Minevikumälestused". Mark Soosaare näitusest "Kihnukielsed ljõnnud". Jarek Jõepera ja Jaan Künnapi näitustest. Näitusest "Meil on elu keset metsa" (Veiko Belials jt.). Ulvar Käärt peapreemia saanud Oliver Götzli filmist "Skandinaavia loodus - Soome" (Saksamaa)

  5. Maagiline Matrix - muutuste võti / Marika Makarova ; kommenteerinud Ainar Leppik

    Makarova, Marika

    2010-01-01

    USA kiropraktiku Richard Bartletti loodud Matrix Energetics tehnikate alusl Ainar Leppiku poolt loodud Maagilise Maatriksi meetodist, mis õpetab muutuste toomist oma ellu. Vestlustest Maagilise Maatriksi õpetajatega

  6. Uut Kristjan Palusalu põgenemisloos / Kristjan Palusalu ; kommenteerinud Paavo Kivine

    Palusalu, Kristjan, 1908-1987

    2015-01-01

    Palusalu ülekuulamisprotokoll. Protokollis on juttu Eesti oludest bolševiseerimise aegadel, metsavennasalkadest, mobiliseerimisest, teekonnast läbi Põhja-Venemaa, nn troika kohtust, bolševike-aegsetest vanglaoludest, rahva meelsusest bolševike võimu ajal, spordioludest

  7. Puitmaterjali hinnatõus sirutab tiibu. Ees ootamas toorme nappus / Tea Taruste ; kommenteerinud Marti Rehemaa

    Taruste, Tea

    2011-01-01

    Firmajuhtide prognoose puiduhinna kohta. Puukeskuse müügimaht kasvas 2010. aastal 2009. aastaga võrreldes 10%, 2011.a. jaanuaris 30%. Puitkarkass-, element- ja moodulmaju tootev RPM Grupp ostab suuremõõdulisi prusse Venemaalt või Lätist, palkmaju tootval Hobbiton OÜ-l on toorme saamiseks leping RMK-ga

  8. Puhkus moodsas kalurikülas / Karen Jagodin ; kommenteerinud Indrek Mikk, Raivo Kotov

    Jagodin, Karen, 1982-

    2009-01-01

    GoSpa residentsid Kuressaares. Arhitektid: Indrek Mikk, Raivo Kotov (KOKO Arhitektid). Sisearhitekt: Kätlin Ölluk. Projekt: 2007, valmis: 2009. Suvitajatele mõeldud viiest kahekorruselisest hoonest koosnev ansambel on liigendatud mahtude ja lehisepuidust-betoonist fassaadidega. Terrassid ja rõdud avanevad peamiselt suunaga merele. Kortereid saab endale osta või üürida

  9. Sarnaneme ja eristume vormirõiva abiga / Britt Samoson ; kommenteerinud Katrin Kuldma

    Samoson, Britt, 1982-

    2010-01-01

    Jaana Varkki ja Erkki Engso disainitud EXPO Shanghai 2010 maailmanäituse Eesti Paviljoni tiimitöötajate vormirõivastest. Rahvusooper Estonia ning Nokia kontserdimaja teenindajate rõivaid tutvustab nende looja Katrin Kuldma

  10. Reformierakonna varjatud arved / Kadri Jakobson, Kadrin Karner, Koit Brinkmann ; kommenteerinud Carol Merzin

    Jakobson, Kadri, 1970-

    2009-01-01

    Riigiprokuratuur leidis, et Jaanus Rahumägi ja Robert Antropov rahastasid oma valimiskampaaniat ise ning tegu ei olnud Reformierakonna kampaaniga. Tabel: Reformierakonna riigikogu valimiskampaaniaga seotud kulud, mida erakond pole deklareerinud

  11. Teatrikunstnik Iir Hermeliin - maagiline realist / Iir Hermeliin ; intervjueerinud Tiina Kolk, kommenteerinud Dmitri Demjanov, Evelin Kattai

    Iir Hermeliin, pseud., 1973-

    2010-01-01

    Iir Hermeliini (Hille Ermel) teatritööst, talle olulistest paikadest Eestimaal, elust Kalamajas, välisreisidest, huvist kokanduse vastu, kunstiõpingutest, inspiratsiooniallikatest. Loetletud saadud autasud, valik lavastusi

  12. "Parlament 95" = "Parliament 95" / Ionel Lehari, Janno Roos ; kommenteerinud Illi Ong

    Lehari, Ionel, 1967-

    2015-01-01

    Rändnäitus "Parlament 95" Eesti suuremate linnade kaubanduskeskustes. Autorid Janno Roos, Andres Labi (Ruumilabor), Ionel Lehari, Maret Põldre (Identity), Taavi Rull. Eesti Sisearhitektide Liidu aastapreemia 2014/2015 parima installatsiooni eest

  13. Äpardunud sambameistrid said viimaks hundipassi / Urmas Jaagant, Tuuli Aug ; kommenteerinud Rainer Sternfeld

    Jaagant, Urmas

    2009-01-01

    Tšehhi firma Sans Souci ei suutnud Vabadussõja võidusamba ristiosa valgustust rahuldaval määral tööle saada. Uue valguslahenduse leidmiseks on kaitseminister Jaak Aaviksoo palunud algatada riigihanke. Vabadussamba autori Rainer Sternfeldi arvamus tšehhide kehva töö kohta

  14. Minimalism, sooja südamega / Malle Pajula, Eva Toome ; kommenteerinud Riina Harik

    Pajula, Malle, 1971-

    2009-01-01

    Perekond Kremmi napi ja läbimõeldud kujunduse ning tervikliku valguslahenduse ja välibasseiniga eramust Tiskres, mis pälvis konkursil "Kaunis Kodu 2008" sisekujundaja kaasabil loodud kauneima kodu tiitli

  15. Priitahtlik pension pürgib palgalisaks / Kadri Paas ; kommenteerinud Erki Kilu

    Paas, Kadri, 1982-

    2010-01-01

    Kogumispensioni seaduse eelnõust, mis näeb ette, et ettevõtjatele võimaldatakse teha oma töötajate eest sissemakseid vabatahtlikku pensionifondi või täiendava kogumispensioni kindlustuslepingusse kohustuseta tasuda erisoodustuse tulumaksu. Kommenteerib Erki Kilu

  16. Uma Pido - kohalike laulupidude võrukeelne majakas / Kristel Kossar ; kommenteerinud LaineJänes

    Kossar, Kristel

    2010-01-01

    29. mail 2010. aastal Intsikurmus toimuvast võrukeelsest laulupeost "Uma Pido". Laulupeo projektijuht Triinu Ojari ja laulukirjutaja Aapo Ilvesega eelseisvast peost. Kommentaar kultuuriminister Laine Jäneselt

  17. Elisa Studio showroom = Elisa Studio showroom / Jan Joonas Graps ; kommenteerinud Tiina Kuusisto

    Graps, Jan Joonas, 1972-

    2015-01-01

    Elisa Studio showroom Helsingis Lasiplatsi, Mannerheimintie 22-24. Sisekujunduse autorid Jan Joonas Graps, Ken-Kristjan Ruut, Anne Määrmann (JanKen Wisespace). Lühidalt loovstuudiost JanKen Wisespace

  18. Rate.ee asutaja tuleb turule sotsiaalse aktsiafondiga / Katre Pilvinski ; kommenteerinud Sven Kunsing

    Pilvinski, Katre

    2010-01-01

    Rate.ee asutaja Andrei Korobeinik toob turule sotsiaalse aktsiafondi cutefund.com, mille puhul otsustavad investorid ise milliseid aktsiaid osta ja müüa. Ettevõtete inkubaator The Difference Engine pakkus Korobeinikule võimaluse osaleda oma mentorlusprogrammis

  19. Ülemiste kaubanduskeskus = Ülemiste shopping center / Priit Põldme ; kommenteerinud Linda Madalik

    Põldme, Priit, 1971-

    2015-01-01

    Ülemiste kaubanduskeskus Tallinnas Suur-Sõjamäe 4. Sisekujunduse autorid Priit Põldme, Reet Sepp (sisearhitektuuribüroo Joonprojekt); arhitektid Einar Aakeroy (AMB Arkitekter), Lauri Laisaar, Ingel Sirkel-Suviste, Jaanika Oks, Katrin Kõlu (Novarc Group AS). Lühidalt Priit Põldmest ja Reet Sepast

  20. Kaidar Kivistik õpetab inglise keelt kultuuri kaudu / intervjueerinud Tiina Vapper ; kommenteerinud Margarita Eero

    Kivistik, Kaidar

    2016-01-01

    Tallinna Kanutiaia noortemajas on võimalik osa saada koolidele mõeldud rahvusvahelisest haridusprogrammist „Learning Without Borders” (piirideta õpe), mille eesmärk on tutvustada kultuuripõhist inglise keelt. Intervjuu ühe töötubade ja etenduste läbiviija Kaidar Kivistikuga

  1. Rootsi soovitab pangad maksustada / Kadri Bank ; kommenteerinud Tanel Ross, Ivari Padar

    Bank, Kadri

    2010-01-01

    Rootsi rahandusminister Andres Borg tegi Euroopa Liidu liikmesriikide rahandusministritele ettepaneku järgida Rootsi eeskuju ning maksustada pangad, ettepaneku jõustumisel peaksid Eesti pangad maksma loodavasse stabiliseerimisfondi umbes 50 miljonit krooni aastas

  2. Saksa Trakeeni Liidu külaskäik Peroni juurde / Maario Laas ; kommenteerinud Peeter Viiard

    Laas, Maario

    2014-01-01

    14.-17. veebruarini külastasid Eestit Saksamaa Trakeeni Liidu turundus ja spordijuht Andre Hahn ning Andreas Loebnitz omanimelisest trakeenikasvandusest, eesmärgiga tutvuda Eestis kasvatatavate trakeenidega ja teha kaupa Trakehner Hengstmarketil ning Neumünsteri galashowl sakslastele silma jäänud Peroni asjus

  3. Indrek Kasela, Hamlet ärimaailmas / Indrek Kasela ; intervjueerinud Priit Pullerits ; kommenteerinud Maarja Neilvelt

    Kasela, Indrek, 1971-

    2010-01-01

    Ettevõtja, kino Sõprus taasavaja ning Premia börsile viija Indrek Kasela oma tegevusest fondihaldurina, New Yorgi ülikoolis saadud kogemustest, Eesti ühiskonnakorralduses vaja minevatest muutustest

  4. Juhtimisülesanne : ja kalad saavad ka kinga / Ergo Metsla ; kommenteerinud Algis Perens, Liis Luuk

    Metsla, Ergo, 1968-

    2010-01-01

    Juhtimisülesanne, kus ettevõte on pärast turu kokkulanemist sattunud majanduslikesse raskustesse ning ettevõtte juhid on valiku ees, kas lõhkuda aastaid koos töötanud meeskond ja koondada töötajaid või leida firma püsimajäämiseks mõni muu variant. Lahendust otsivad konsultantsioonifirma Helvetia Balti Partnerid juhatuse esimees Algis Perens ja Kalev SPA Veekeskuse müügi- ja turundusassistent Liis Luuk

  5. Õigusabi vähekindlustatuile / Mari Kasela ; kommenteerinud Maire Arm

    Kasela, Mari

    2011-01-01

    Tasuta õigusabi majandus- ja makseraskustesse sattunud peredele pakub Eesti Juristide Liidu õigusportaal, esmase õigusabi teenust pakuvad Eesti Juristide Liit, sihtasutus Õigusteenuste Büroo Tallinnas, Üliõpilaste Õigusbüroo Tallinnas, Eesti Advokatuuri ja Lastekaitse Liidu koostööprojekt "Hea nõu lastega peredele"

  6. Teletorn muutub magnetiks / Oliver Õunmaa ; kommenteerinud Aare Siimon, Raili Paling

    Õunmaa, Oliver

    2010-01-01

    Aprillis algab aasta aega kestev Tallinna teletorni remont, mille käigus tehtavate muudatuste kohta jagavad selgitusi torni haldava ettevõtte Levira finantsdirektor Aare Siimon ja Arhitektuuribüroo Koko arhitekt Raili Paling

  7. Vaprad lucky loser'id / Jüri Aarma ; kommenteerinud Tanja Muravskaja

    Aarma, Jüri, 1951-

    2009-01-01

    Tanja Muravskaja isikunäitus "Lucky Losers" Tallinna Linnagaleriis. Eksponeeritud videoportreed vene rahvusest Eesti kodanikest Dimitri Klenskist, Adolf Käisist, Anna Levandist, Tatjana Muravjovast, Mihhail Stalnuhhinist, Eduard Tomanist ja Boris Tuchist

  8. Tere tähed! : tähejooga õpetab lugema / Krista Kivisalu ; kommenteerinud Kristel Paimla

    Kivisalu, Krista, 1968-

    2016-01-01

    Vestlusest MTÜ Hooling lugemisnõustaja, koolitaja ja Eesti Lugemisühingu juhatuse liikme Maili Liineviga. Lugemisjooga on uus mänguline meetod, mis ühendab Kundalini lastejooga ja lugemise algõppe

  9. Imevaip kui majanduse šanss / Sulev Oll ; kommenteerinud Ants Reinumägi

    Oll, Sulev, 1964-

    2010-01-01

    Ekspordiks tootvad Eesti ettevõtted on uuel tõuslainel - teenivad kasumit ja värbavad uusi töötajaid. Vaibatootja Narma LV, metallkonstruktsioonide valmistaja OÜ Contractor, elektrimootorite komponentide tootja AS Kolmeks

  10. Kino Kosmos Imax = Kosmos Imax cinema / Pille Lausmäe ; kommenteerinud Karen Jagodin

    Lausmäe, Pille, 1958-

    2015-01-01

    Kino Kosmos Imax Tallinnas Pärnu mnt 45. 1964. aastal valminud hoone arhitekt Ilmar Laasi. Renoveeritud interjööri autorid Pille Lausmäe, Kerli Lepp (Pille Lausmäe Sisearhitektuuri büroo). Projekti autorid Urmas Lõoke, Riina Poopuu (Urmas Lõokese Arhitektibüroo)

  11. Raginal rannavormi / kommenteerinud Reet Puks, Merily Lehis, Helle Nurmsalu, Galina Sepp

    2010-01-01

    Ilusalongides pakutavatest salendavatest kehahooldusprotseduuridest aparaatidega - LPG edermoloogiline massaaž, Universal Contour Wrap, ULTRATONE intensiivne tselluliidiravi ja mittekirurgiline facelift, Shockmaster AWT meetod (akustilise laine ravi)

  12. Hollandlaste dramaatiline lähenemine teadusele / Eero Loonurm ; kommenteerinud Reimo Rehkli, Mathis Bogens

    Loonurm, Eero

    2016-01-01

    Hollandi teaduspõhine ettevõte Royal DSM võitis 2016. a. Euroopa parima ettevõtte kommunikatsioonimeeskonna auhinna kampaaniaga "Teadus võib muuta maailma". Brändikampaaniaga sooviti näidata oma tõelist pühendumist, juhtida tähelepanu teaduse kasutegurile ühiskonnas, inspireerida avalikkust lühikese videoklipiga teadlaste argipäevast ning tugevdada sidet ettevõtte töötajatega

  13. Sõjaraamatu hävitamisel on seos Eestiga / Hendrik Vosman, Tuuli Koch ; kommenteerinud Jaak Aaviksoo

    Vosman, Hendrik

    2011-01-01

    Suurbritannia ajakirjaniku Toby Harndeni Afganistani sõda käsitlevast raamatust "Dead Men Risen: The Welsh Guards and the Real Story of Britain's War in Afganistan" ("Ülestõusnud surnud: Walesi kaardivägi ja tegelik lugu brittide sõjast Afganistanis"). Briti kaitseministeerium lükkab ümber Harndeni väite raamatu ümber puhkenud skandaali poliitilisest tagamaast, autori arvates kartis kaitseministeerium, et raamatus leiduv info võiks Eestit ärritada

  14. Kahtlejate osakaal on kasvanud 44 protsendile / Kärt Anvelt ; kommenteerinud Kalev Petti

    Anvelt, Kärt, 1973-

    2011-01-01

    Autor käsitleb viimaseid valimiste-eelseid küsitlusuuringuid ning märgib, et kahtlejaid on enim endiste Reformierakonna toetajate seas ning valimiste tulemuse seisukohalt näib olevat võtmeküsimus, kas Reformierakonna valija taastab oma eelistuse ja tuleb valima või mitte. Diagrammid, graafikud

  15. Eesti saab kaasaegse veiste kogumise keskuse / Lii Sammler ; kommenteerinud Aldo Vaan

    Sammler, Lii, 1963-

    2016-01-01

    Oktoobris avab Eesti Tõuloomakasvatajate Ühistu Harjumaal Kaunissaares loomade kogumiskeskuse. See annab võimaluse loomad enne eksporti kokku koondada ja vajalikud uuringud teha. Vestlusest Eesti Tõuloomakasvatajate Ühistu juhatuse esimehe Tanel Bulitkoga

  16. Oktoober oli kasumiteenimise kuu / Fredy-Edwin Esse ; kommenteerinud Kristjan Hänni

    Esse, Fredy-Edwin

    2010-01-01

    Nii Tallinna kui ka Vilniuse börs kuulusid oktoobris maailma kümne enim tõusnud aktsiaturu hulka, Tallinna börs on viimase nelja kuu jooksul kasvanud 26,9%. Kõige rohkem tõusis oktoobris Shanghai börs. Kallinemisest toorainete turul

  17. Arendajad asuvad julgelt uute projektide kallale / Tea Taruste ; kommenteerinud Andres Teder

    Taruste, Tea

    2010-01-01

    Arco Vara ehitab kortermaju Tallinnas Kodukolde elurajooni ning on alustanud Kodukolde uue etapi korterite müüki, NCC alustas Vana-Kuuli III etapi ehitust ning jätkab Pärnaõue elamuprojekti arendust

  18. IT-ettevõtted edust üllatunud / Katre Pilvinski ; kommenteerinud Linnar Viik

    Pilvinski, Katre

    2010-01-01

    Äripäeva kiiresti kasvavate ettevõtete ehk gasellide edetabeli edukaimatest IT-ettevõtetest Sportradar OÜ, Sona Systems ja Hansson, Leego & Partner juhid ning maailma parimatest IT-gasellidest Research In Motion ja Sigma Designs. Ettevõtete juhtide kommentaare

  19. Veebipõhised õppematerjalid ja ühistöö / Sirle Budris ; kommenteerinud Kadri Kaska

    Budris, Sirle

    2009-01-01

    Teoste tsiteerimisest, refereerimisest ja kasutamisest õppetöös vastavalt autoriõiguse seadusele. Teoste varalistest õigustest, õppematerjalide muutmisest ja avaldamisest veebis, litsentside kasutamisest ja õppematerjalide koostamisest. Joonised

  20. Pangad nopivad odava kinnisvara / Birjo Must ; kommenteerinud Hannes Kuhlbach, Meelis Šokman

    Must, Birjo

    2010-01-01

    Võrreldes 2010. a. algusega on SEB makseraskustes klientidelt ostetud kinnisvara mahu neljakordistanud, Swedbank on mahu enam kui kahekordistanud. Kommenteerivad SEB kinnisvarahaldusfirma Estectus OÜ juht Hannes Kuhlbach ja Swedbanki Eesti kinnisvarahalduse ettevõtte Ektornet Residential Estonia OÜ juht Meelis Šokman

  1. Suurõppus valmistas linlastele peavalu / Mari Mets ; kommenteerinud Margus Kotter

    Mets, Mari

    2011-01-01

    17. mail toimus Tartus suur kriisiõppus EU CREMEX 2011, mille stsenaariumi järgi sattus õnnetusse ohtlikke kemikaale vedanud vagun ja tekkis radioaktiivsuse oht. Õppuse käigus evakueeriti ligi 500 Tähtvere elanikku

  2. Ühe saarma lugu / Silja Kana ; kommenteerinud Val Rajasaar, Teet Koitjärv

    Kana, Silja

    2012-01-01

    Mida teha kui juhtute otsa sõitma jahiulukile, I või II kategooria kaitsealusele liigile. Lugu saarmast, kes hukkus kokkupõrkel autoga, kuid kellest tänu teadlikele inimestele valmib topis-õppevahend Keskkonnaameti tellitud komplektis Valgamaale

  3. Mets ja marutaud / Merje Ottson ; kommenteerinud Kalev Männiste, Kaja Kübar, Enel Niin

    Ottson, Merje

    2011-01-01

    Marutõvest ja marutaudist. Rebaste ja kährikute marutaudi vastase vaktsineerimise mõjust loomade arvukuse kasvutegurina ning nende põhjustatud ohust lindude, peamiselt metsislaste, ja näriliste arvukusele ning jahimeeste osast rebaste ja kährikute arvukuse piirajana.

  4. Õhuloss ehk tuletorni juurde / Tiina Käesel ; kommenteerinud Tamara Luuk

    Käesel, Tiina, 1943-

    2011-01-01

    Ehtekunstinäitus "Õhuloss" Tallinna Põhjatuletornis 25. septembrini 2011. Näitusega kaasneb raamat "Castle in the Air - Jewellery from Estonia - Õhuloss", koostajad Kadri Mälk ja Tanel Veenre. Rühmitusse "õhuLoss" kuuluvad Kadri Mälk, Piret Hirv, Eve Margus-Villems, Kristiina Laurits, Villu Plink, Tanel Veenre, Katrin Sipelgas

  5. Reform andnuks kirevama riigikogu / Alo Raun ; kommenteerinud Martin Mölder

    Raun, Alo, 1981-

    2011-01-01

    Juhul kui Riigikogu oleks kokku pandud üleriigiliste nimekirjadeta, oleks sinna pääsenud nelja asemel kuus erakonda, lisaks kaks üksikkandidaati, Reformierakonna ja IRLi koalitsioon oleks kahanenud 52 mandaadile

  6. Ekspert: poerohkus ajab Eesti hinnad kõrgeks / Katre Pilvinski ; kommenteerinud Raul Puusepp

    Pilvinski, Katre

    2010-01-01

    Kanada Guelphi ülikooli turundus- ja kaubandusprofessor Brent McKenzie leiab, et Eesti jaekaubandusturul on liiga palju erinevaid super- ja hüpermarketeid ning seetõttu pole jaemüüjatel suurt mõju varustajatele

  7. Nia - rõõm liikumisest / Monica Raud ; kommenteerinud Sirje Sinisoo

    Raud, Monica, 1981-

    2014-01-01

    1983. aastal Debbie ja Carlos Rosaśide poolt üheksast liikumistehnikast - taekwondo, aikido, taiji, dšässtants, moderntants, Isadora Duncani tants, Feldenkraisi meetod, Aleksanderi tehnika ja jooga - sünteeritud liikumisõpetusest

  8. Esileedi Evelin Ilves läheb Kaleviga kommisõtta / Priit Pullerits ; kommenteerinud Monika Heinrand

    Pullerits, Priit, 1965-

    2009-01-01

    Liikuvat eluviisi ja tervislikku toitumist propageeriv proua Evelin Ilves on otsustanud alustada võitlust transrasvhappeid sisaldavate toiduainete vastu. Proua E. Ilves koostas nimekirja maiustustetootja Kalevi kommidest, mis märgistuse järgi sisaldavad transrasvu. Arvamust avaldavad Kalevi turundus- ja müügidirektor Monika Heinrand, kirjanik Andrus Kivirähk, koduperenaine Kadi Tarand, Tallinna Tehnikaülikooli toiduainete instituudi direktor professor Raivo Vokk. Vastukajad artiklile vt. Postimees 30. sept. 2009, lk. 15: Petrone, Epp. Poes tuleb tähelepanelik olla; Tuiksoo, Ester. Hoidkem Eesti toitu ja toiduainetetööstust; Õhtuleht 3. okt. 2009, lk. 7: Kerge, Rainer. Mahetomat tapab!; Eesti Päevaleht 5. okt. 2009, lk. 2: Teemägi, Tiina. Aasta turundustegu; Pehme, Sirli. Transrasvu tuleb vältida; Õhtuleht 5. okt. 2009, lk. 8: Kummardus Evelinile!; Rulluisud ja transrasvad; Terviseleht 6. okt. 2009, lk. 2: Laane, Aleksander. Solaariumid ja transrasvad; Postimees 13. okt. 2009, lk. 12-13: Strider, Roy. Kellele on transrasvad kasulikud?; Kambek, Liis. Transrasvhapped on üleilmne probleem; Postimees 17. okt. 2009, lk. 14: Kuusk, Hendrik. Toidupoes ei müüda mürgikokteile; Õhtuleht 24. okt. 2009, lk. 9: Levin, Adik. Igaühel on õigus toituda tervislikult; Eesti Päevaleht 27. okt. 2009, lk. 3: Trisberg, Aet. Luubiga poodi; Postimees : AK 5. dets. 2009, lk. 12 karikatuur transrasvade teemal

  9. Nord Stream tuleb Venemaa gaasihiiule raskel ajal / Jaanus Piirsalu ; kommenteerinud Mihhail Kortšemkin

    Piirsalu, Jaanus, 1973-

    2010-01-01

    Gazpromi tähtsus "energeetikarelvana" on hakanud kahanema - Euroopas on gaasi tarbimine vähenenud, mitmed gaasitootjad pakuvad Euroopale Vene gaasiga hinna poolest edukalt konkureerivat vedelgaasi, USA-s toodetakse üha enam kildagaasi

  10. Mida teha Lätiga? / Mari Kooskora ; kommenteerinud Marta Piigli, Endel Hango

    Kooskora, Mari, 1969-

    2009-01-01

    Juhtimisülesanne, kus rahvusvahelises ettevõttes töötav regiooni direktor peab lahendama oma alluvuses olevas tütarettevõttes tekkinud vastuolud. Lahendust otsivad Vendor Eesti OÜ turundusjuht Marta Piigli ja SELF II koolitaja Endel Hango

  11. Info- ja kommunikatsioonitehnoloogia arenguseire järeldused ja soovitused = Information and communication technologies foresight: conclusions and policy recommendations / Kristjan Rebane

    Rebane, Kristjan

    2010-01-01

    Eesti Arengufondi arenguseirest, mille eesmärgiks oli kindlaks teha, millised valdkonnad suudavad järgmise 10. aastaga info- ja kommunikatsioonitehnoloogia abiga Eesti majanduse ja ühiskonna arengusse enim panustada. Joonised

  12. Gümnasistid kipuvad kooli kõrvalt tööle / Kaarel Kotkas, Mariliis Kaul, Helis Toiger, Elar Toomsalu ; küsitlenud Madde Rebane

    2007-01-01

    Intervjuu Pärnu gümnaasiumiõpilaste Kaarel Kotkasega Hansagümnaasiumist, Mariliis Kauliga Koidula Gümnaasiumist, Helis Toigeriga Ülejõe Gümnaasiumist ja Elar Toomsaluga Sütevaka Humanitaargümnaasiumist

  13. Aino Kalda päevikud : Valgus ja varjud ; Valguse ja varju segu ; Hingesillad ; Rikas, kuhjaga täis / Hilve Rebane

    Rebane, Hilve, 1938-2012

    2003-01-01

    Arvustus: Kallas, Aino. Pärjapunuja. Päevaraamat aastaist 1897-1900. Tallinn : Eesti Raamat, 1994 ; Kallas, Aino. Jäätunud šampanja. Päevaraamat aastaist 1907-1915. Tallinn : Eesti Raamat, 1994 ; Kallas, Aino. Hingesild. Päevikulehti aastaist 1916-1921. Tallinn : Eesti Raamat, 1993 ; Kallas, Aino. Suurlinnade udus ja säras. Päevaraamat aastaist 1922-1926. Tallinn : Eesti Raamat, 1996 ; Kallas, Aino. Pööripäevad. Päevaraamat aastaist 1927-1931

  14. Kuld ja pruun, kuld ja purpur : Uusaegsest köitekunstist Kaspar Meuseri raamatuköite näitel / Liia Rebane

    Rebane, Liia

    2010-01-01

    Soome Rahvusraamatukogust leitud rariteetsest raamatuköitest, mis atribueeritud Kaspar Meuserile ja on täienduseks varasematele Krause-Meuseri ning renessanssköidete uurimustele. Ka saksa raamatuköite ajaloost üldisemalt, eriti 16. sajandil

  15. Valme / Aisopos ; tlk. Kaarina Krull

    Aisopos, 6.saj. e.Kr.

    1999-01-01

    Sisu : Rebane ja leopard; Rebane ja koomiline mask; Pime; Inimesed ja Zeus; Inimene ja saatür; Vanamees ja surm; Rändur Diogenes; Zeus ja inimesed; Zeus, Prometheus, Athena ja Momos; Herakles ja Plutos; Mees kes kitaara saatel laulis

  16. Estonian mills are going to live again : there are twice as many mills in Estonia as there are manors, but most of them are in ruins / Urmas Vahe

    Vahe, Urmas

    2002-01-01

    Veskite ja hüdroelektrijaamade rajamise ajaloost, taastamisest ning kasutamisest tänapäeval. Alternatiivsed elektrijaamad kui keskkonna osa. Tabel: Eesti hüdroelektrijaamad, 2002. Kommenteerinud Inge Roos

  17. Kolmekesi ühest Peipsi-äärsest asjast / Tiit Lepp

    Lepp, Tiit

    2007-01-01

    Annika Haasi, Birgit Püve ja Age Petersoni fotonäitus "Prichudie, Revisited" Peipsiääre valla inimestest ja elust-olust kunstikeskuses AmbulARToorium Tartumaaal. Kommenteerinud Annika Haas, Birgit Püve, Age Peterson

  18. Raamat sõja seadustest / Linnart Mäll

    Mäll, Linnart

    2001-01-01

    Vana-Hiina sõjateoreetikute Sun Zi ja Sun Bini raamatust: Sun, Zi ; Sun, Bin. Sõja seadused / klassikalisest hiina keelest tõlkinud ja kommenteerinud Märt Läänemets. Tln. : Eesti Keele Sihtasutus, 2001. (Sõjandusvaramu. Klassika)

  19. Kodud mitme mere ääres / Viivi Variksaar

    Variksaar, Viivi, 1948-

    2001-01-01

    Ameerikas Hilton Headis elavatest väliseestlastest Erle ja Elmo H. Sergost, nende korterist Tallinnas Poska tänaval. Seintel olevad pildid on maalinud ja kodu kujundanud Erle Sergo. Kommenteerinud Elmo H. Sergo, Erle Sergo. 8 ill

  20. Natura 2000 sai tuule tiibadesse Raplamaal / Ain Aivela

    Aivela, Ain

    2004-01-01

    Natura 2000 idee jõudis Eestisse 2000. aastal, mil pilootprojekti raames ning Taani riigi rahalisel toel alustati Natura-võrgustiku eelvalikualade mahamärkimist Lääne- ja Raplamaal. Kommenteerinud Aleksei Lotman

  1. Maagiliste momentide mütoloogia : intervjuu Peter Cook'iga / Peter Cook ; interv. Vilen Künnapu

    Cook, Peter

    2002-01-01

    5. Põhja- ja Baltimaade Arhitektuuritriennaalil esinenud inglise arhitekt P. Cook endast, oma loomingust, rühmitusest Archigram, mis pälvis 2002. a. RIBA (Royal Institute of British Architects) kuldmedali, Tallinnast jm. Kommenteerinud Triin Ojari

  2. Kihnu kultuur pälvis koos laulupeoga tunnustuse / Neeme Korv

    Korv, Neeme, 1974-

    2003-01-01

    Kihnu kultuuriruumi ja Balti riikide laulu- ja tantsupidude traditsiooni kandmisest UNESCO maailma vaimse ja suulise pärandi nimekirja, materjal aadressli www.unesco.ee/kihnu.pdf. Kommenteerinud Mark Soosaar

  3. [Raamat] / Kaja Tiisel

    Tiisel, Kaja

    2007-01-01

    Rets. rmt.: Jõelähtme kirik ja kogudus 18. sajandi esimesel poolel. Pastor Heinrich Christopher Wrede ja tema ametijärglaste kroonikamärkmed. Transkribeerinud, tõlkinud ja kommenteerinud Tiina Kala. Tallinn : Muinsuskaitseamet, 2006. 420 lk.

  4. Kolmesaja aasta tagune kroonika sai raamatuks / Meeli Pärtelpoeg

    Pärtelpoeg, Meeli, 1965-

    2006-01-01

    Rmt.: Jõelähtme kirik ja kogudus 18. sajandi esimesel poolel. Pastor Heinrich Christopher Wrede ja tema ametijärglaste kroonikamärkmed / transkribeerinud, tõlkinud ja kommenteerinud Tiina Kala. Tallinn : Muinsuskaitseamet, 2006

  5. Ene Üleoja: "Kreeki ei ületa praegu keegi" / Ene Üleoja ; intervjueerinud T[iina] M[attisen

    Üleoja, Ene, 1937-

    2010-01-01

    Heliloojate Liidu ja Pirita kloostri poolt välja kuulutatud heliloominguvõistluse "Taaveti laul" tulemustest žürii liikme E. Üleojaga. Konkursi lõppkontsert toimus 10. veebr. Pirita kloostris, esines Voces Musicales Endrik Üksvärava juhatusel

  6. Eesti keelenõuded kohati Venemaa omadest leebemad / Jaanus Piirsalu ; kommenteerinud Mart Rannut, Mart Nutt, Valeria Jakobson

    Piirsalu, Jaanus, 1973-

    2011-01-01

    Eesti välisministeerium tüdines Moskva pidevast kriitikast keelepoliitika karmuse kohta ning lasi teha Eesti ja Venemaa keelenõuete võrdleva analüüsi, mille tulemuste järgi on Venemaa nõuded kohati isegi karmimad

  7. Andres Tolts 60 : omanäoliste vaikelude imeline maailm / Andres Tolts ; intervjueerinud Tiina Kolk ; kommenteerinud Jaan Elken

    Tolts, Andres, 1949-2014

    2009-01-01

    Andres Toltsi näitused "Asjad" Hobusepea galeriis 12. oktoobrini, "Näitus" Tallinna Kunstihoones 25. oktoobrini, "Varane Tolts" Haus galeriis 13. novembrini. Pikemalt näitusest "Näitus", kuraator Harry Liivrand

  8. Doktorant lahendab juustulehma valemit : Tartu noorte teadlaste artikkel tõusis poodiumile / Martin Pau ; kommenteerinud Ursel Soomets

    Pau, Martin, 1975-

    2012-01-01

    Teadusajakirja Journal of Dairy Science oktoobrinumbri artikli «Piimalehmade piima ja vere metaboloomi muutused esimeste laktatsioonikuude jooksul» kaasautori, maaülikooli doktorandi Hedi Harzia uurimistööst

  9. Just nagu mustkunst: võlgades firmad haihtusid politseinike ja maksuametnike silme all / Marta Jaakson ; kommenteerinud Marie Rosin

    Jaakson, Marta

    2017-01-01

    Maksuvõlgadega firmad Lõuna Ehitus OÜ, EBG OÜ, Lõuna Ehitus Grupp OÜ, Joy Grupp OÜ, Caramira Pet Trade OÜ, Väike-Ameerika 2 OÜ, Legal & Business Solutions OÜ ühinesid Verones OÜ-ga ning kustutati äriregistrist ja võlad jäävad likvideerijate mureks

  10. TÜ Loodusmuuseum = University of Tartu Natural History Museum / Raili Paling, Liis Lindvere, Kadri Kaldam ; kommenteerinud Jana Lass

    Paling, Raili

    2016-01-01

    Tartu Ülikooli Loodusmuuseumi (Tartu, Vanemuise tn. 46) interjöör ja ekspositsioon. Autorid Jelena Altmäe, Kadri Kaldam, Raivo Kotov, Andrus Kõresaar, Lea Laidra, Liis Lindvere, Indrek Mikk, Jaanus Männik, Raili Paling; projektijuht Reet Mägi; kuraatorid Kaie Kotov, Riste Keskpaik

  11. Arvo Pärt jagab preemia koolidele / Rebekka Lotman, Eva Kübar ; kommenteerinud Arvo Pärt

    Lotman, Rebekka, 1978-

    2009-01-01

    Kultuuriministeerium tegi ettepaneku anda Arvo Pärdile elutööpreemia, millega kaasneva rahasumma lubas Pärt kinkida Rakvere ja Paide muusikakoolile. Elutööpreemiad saavad veel Ellen Niit ja Aarne Üksküla

  12. Oskusest konflikti sekkuda on töös tuge / Sirje Pärismaa ; kommenteerinud Airiin Demir

    Pärismaa, Sirje, 1958-

    2016-01-01

    Projekti „Tõenduspõhine uus lähenemine - uus koolikultuur Eestis (TULUKE)“ üheks alategevuseks on pädevuste arendamine tõenduspõhiste sekkumisprogrammide kasutuselevõtuks. Maarjamaa hariduskolleegiumi Emajõe õppekeskuse (endine Kaagvere erikool) töötajad on õppinud maailmas tunnustatud sekkumisprogrammide nippe

  13. Õppetoetuste semantikast / Eleene Sammler ; kommenteerinud Siim Kanne, Kerstin Kruusmaa, Maarja Mälberg, Mihkel Tedremaa

    Sammler, Eleene

    2009-01-01

    Õppetoetuste jagamisest suuremates Eesti ülikoolides. Kommenteerivad Tartu Ülikooli füüsika 1. kursuse üliõpilane Siim Kanne, EMÜ maastikuarhitektuuri 1. kursuse üliõpilane Kerstin Kruusmaa, Tallinna Ülikooli riigiteaduste eriala 2. kursuse üliõpilane Maarja Mälberg ja TTÜ mehhatroonika 1. kursuse üliõpilane Mihkel Tedremaa

  14. Uuendusi vangistusest tingimisi ennetähtaegsel vabastamisel / Anne Rannaveski-Poola, Anne Kruusement ; kommenteerinud Kadri Kelder, ... [jt.

    Rannaveski-Poola, Anne

    2007-01-01

    Alates 1. jaan. 2007 hakatakse ennetähtaegselt vanglast vabastamisel kasutama elektroonilist valvet. Lisatud: mida toovad muudatused kinnipeetavate ennetähtaegsel vabastamisel kaasa kriminaalhooldajale? Küsimusele vastavad Tartu Maakohtu kriminaalhooldusosakonna juhataja Kadri Kelder, Harju Maakohtu kriminaalhooldusosakonna juhataja Kersti Kask, käitumiskontrolli II talituse juhataja Livia Silvet ja Viru Maakohtu kriminaalhooldusosakonna kriminaahooldusametnikud Gaidi Kasu ja Anton Gontsharov

  15. Tõlkemeistrite 141 selli / Triinu Tamm ; intervjueerinud Pille-Riin Larm ; kommenteerinud Heli Allik, Doris Kareva, Aare Pilv, Alari Allik

    Tamm, Triinu

    2017-01-01

    Eesti Kirjanike Liidu tõlkijate sektsiooni noortele, gümnasistidele ja tudengitele suunatud ilukirjanduse tõlkevõistlusest ja koolitusest. Koos Tallinna ülikooli ja Postimehega käima lükatud uuel tõlkevõistlusel tõlgiti proosatekste vene, prantsuse, inglise ja jaapani keelest. Kommenteerivad tõlkevõistluse žüriide esindajad. Kõige rohkem töid oli Tartu ülikooli üliõpilastelt - 50, Tallinna ülikooli tudengeilt 25, gümnasistide töid oli 59

  16. Teadlased mõõtsid prootoni käitumist / Tiit Kändler ; kommenteerinud Endel Lippmaa

    Kändler, Tiit, 1948-

    2012-01-01

    Eesti liitus Euroopa tuumauuringute keskuse CERN LHC- (ehk suure hadronite põrguti) eksperimendiga 1991. aastal, mil akadeemik Endel Lippmaa eestvõttel hakati koostööd tegema prootonite ehitust uuriva rühmaga TOTEM. Tänaseks on kindlaks tehtud, kuidas prootonile antud energia mõjutab tema vastastikmõju teiste prootonitega

  17. Kamahouse'i asutamise pöörane lugu / Kadri Jakobson ; vahendanud Ursula Zimmermann ; kommenteerinud William Piper

    Jakobson, Kadri, 1970-

    2012-01-01

    Kunsti ja äri ühendamisest: kobarärist Koplis, kuhu kuuluvad Kamahouse Galerii, Eero Kotli Tellisstuudio, Unique Home Art, William Piper konsultatsioonibüroo, Meeskonnakoolituse ja Arenduse OÜ, kauplus-stuudio Õnneküpsis, kohvik Kamahouse'i Köök

  18. Vene noorte jaoks valmib põhjalik Eestit tutvustav patriootlik portaal / Tiina Rekand ; kommenteerinud Roman Fokin, David Vseviov

    Rekand, Tiina, 1985-

    2011-01-01

    Vene noortele luuakse veebileht www.patriot.ee, kus avaldatakse kirjalikke, foto- ja videomaterjale Eesti sümboolikast, venekeelseid artikleid Eesti ajaloolistest tegelastest, ajaloolisi tekste ning Eesti presidentide jt. riigitegelaste parimaid patriootlikke kõnesid

  19. Börs nutab taga Eesti Energia loobumist / Jaana Pikalev ; kommenteerinud Jürgen Ligi, Sandor Liive

    Pikalev, Jaana

    2010-01-01

    SEB privaatpanganduse osakonna strateeg Peeter Koppel, LHV Panga analüütik Sten Pisang, investor Stefan Andresson avaldavad arvamust seoses otsusega Eesti Energia veel mitte börsile viia. Majandus- ja kommunikatsiooniminister Juhan Partsi arvamus

  20. Maksuameti võimatu missioon / Lemmi Kann ; kommenteerinud Lasse Lehis, Rait Kaarma, Taavi Veskimägi

    Kann, Lemmi

    2009-01-01

    Väljavõte artiklist: Maksude optimeerijad tõmmatakse liistule / Lemmi Kann (aripaev.ee, 17.03.2009). Kommenteerivad Eesti Maksumaksjate Liidu juhatuse esimees Lasse Lehis, Alvin, Rödl & Partner Advokaadibüroo OÜ advokaat Rait Kaarma ja Riigikogu liige Taavi Veskimägi

  1. Säästumarketi reklaam pahandab Selverit. Kas halvustab konkurenti või mitte? / Erik Prozes ; kommenteerinud Jana Koppel

    Prozes, Erik, 1970-

    2011-01-01

    Selveri juht Andres Heinver on seisukohal, et Säästumarketi reklaam on tehtud seaduse piirimail. Tarbijakaitseameti esmasel hinnangul on Säästumarketi kaubamärgireklaam kooskõlas reklaamiseaduse põhinõuetega

  2. Camp of Hip-Hop - kõigile kohustuslik / Mari Hiiemäe ; kommenteerinud Joel Juht

    Hiiemäe, Mari

    2012-01-01

    Üheksandat korda toimuvast rahvusvahelisest tantsulaagrist ja tänavakultuuri tutvustavast noortelaagrist Camp of Hip-Hop, mis toimub Lääne Virumaal Käsmus. 28. juunil toimub kõigile huvilistele meelelahutusüritus Camp of Hip-Hop Championships, kus näitavad oma tantsuoskusi laagris osalejad ja maailmas tunnustatud koreograafid

  3. Uni = elu / Lea Noormets ; kommenteerinud Jean-François Bouvet, Marlit Veldi, Tiiu Väinsaar

    Noormets, Lea

    2012-01-01

    Und mõjutavatest teguritest ja unehäirete, s.h ajavahestressi leevendamisest ning ravist homöopaatia, toiduravi, taimravi e fütoteraapia, energeetilise meditsiini või valgusteraapiaga. Artikkel tugineb Gerard Pacaud' raamatule Le Sommeil, c'est vital

  4. Reet Aus, ausa moe nääpsuke saadik / Reet Aus ; intrvjueerinud Britt Rosen ; kommenteerinud Peeter Jalakas

    Aus, Reet, 1974-

    2010-01-01

    Moekunstnik Reet Ausi eluloolisi andmeid, loomingust, karjäärist, edust välismaal. Keskkonnasäästlikust elustiilist ja moest, disainrõivaste tootmisest ja toote hinna kujunemisest. Loetletud teatri- ja filmitööd, võidetud auhinnad, valik näitusi

  5. Sisearhitekt annab panuse : hea disaini mõõdupuuks ratsionaalsus ja omapära / Tea Taruste ; kommenteerinud Loreida Hein

    Taruste, Tea

    2011-01-01

    Tomomi Hayashi, Ahti Grünbergi ja Kerli Valgu projekteeritud ADM Interactive'i bürooruumidest. Sisearhitekt Priit Põldme nõuandeid bürooruumide ümberkujundamiseks. Loreida Heina kommentaar "Bürood uuendades pole mõtet kogu mööblit välja vahetada"

  6. Maailma arhitektuurifestival = World Architecture Festival / Ingrid Ruudi ; kommenteerinud Maarja Kask, Karli Luik, Ralf Lõoke, Indrek Allmann, Martin Aunin

    Ruudi, Ingrid, 1978-

    2011-01-01

    Barcelonas 2.-4. nov. 2011 toimunud 4. Maailma arhitektuurifestivalist (WAF). Muljeid jagavad II vooru pääsenud eesti arhitektid Maarja Kask, Karli Luik ja Ralf Lõoke AB-st Salto (Põhuteater, Sõmeru keskus), Martin Aunin (Must maja Nõmmel), Indrek Allmann AB-st Pluss (poolautonoomne saun). Üldvõitja - Media-ICT Barcelonas (Cloud 9 / Enric Ruiz-Geli)

  7. Gurmaanlus ruulib / Marika Makarova ; kommenteerinud Anu Tali, René Uusmees, Tõnis Siigur, Hannes Võrno, Dimitri Demjanov

    Makarova, Marika

    2010-01-01

    Tulevikutoidu konverentsil Tallinnas esinenud kuulsate kokkade Albert Adria, Fergus Hendersoni ja Claus Meyeri kokakunsti lähtekohtadest ja mõistet gurmaanlus mõtestavad lahti tuntud Eesti inimesed ja kokad

  8. Läbimurre: Enn Kunila saadab oma maalikogu Soome näitusele / Andres Eilart ; kommenteerinud Harry Liivrand

    Eilart, Andres

    2010-01-01

    Helsingi Taidehallis avatakse oktoobri keskel ülevaatenäitus "Viron värit - 150 vuatta virolaista maalaustaidetta Enn Kunilan kokoelmasta" ("Eesti värvid - 150 aastat eesti maalikunsti Enn Kunila kollektsioonist"). Näituse kuraator Harry Liivrand, kujundaja Olev Subbi. Mitmekeelse kunstialbumi koostajaks on kunstiteadlane Eero Epner

  9. Harju maakohus saab Herman Simmi "nimelise" istungitesaali / Holger Roonemaa ; intervjueerinud Jan Jõgis-Laats ; kommenteerinud Andrus Ansip

    Roonemaa, Holger

    2009-01-01

    Tingimustest turvaalale, kus töödeldakse riigisaladusi ja Harju maakohtu istungisaali vastavusest nendele Herman Simmi kohtuasja arutamiseks. Vt. samas lühiinterv.: Ansip: Simm pole meie James Bond

  10. Jõgevamaa Kodukandi Ühendus loob koostöövõrgustikku / Helve Laasik ; kommenteerinud Karina Kaarepere

    Laasik, Helve, 1958-

    2009-01-01

    Jõgevamaa Kodukandi Ühenduse projektist "Koostöö teeb tugevaks", mille käigus luuakse koostöövõrgustik ühenduse ja külaseltside ning kohalike omavalitsuste vahel. Vabaühenduste Fondi toetustest

  11. Eesti tööjõuturg: paindlik või turvaline ? / Mikk Salu ; kommenteerinud Katrin Jaaksoo

    Salu, Mikk, 1975-

    2010-01-01

    Tartu Ülikooli sotsiaalteaduslike rakendusuuringute keskuse RAKE (töögrupi juht Raul Eamets) ja Poliitikauuringute Keskuse Praxis (töögrupi juht Andres Võrk) poolt läbi viidud tööjõu turvalise paindlikkuse (ingl. k. flexicurity) uuringust. Taani mudel

  12. Tähelepanu! Valmis olla! Jääme vanaks... / Luule Sakkeus ; kommenteerinud Bianca Mikovitš

    Sakkeus, Luule, 1956-

    2015-01-01

    Eestis algab kolmas SHARE uuring (Survey of Health, Ageing and Retirement in Europe), mille käigus saadakse ülevaade 50-aastaste ja vanemate elanike tervislikust seisundist ja toimetulekust. Intervjuu TLÜ Eesti demograafia instituudi direktori ja Eesti 50+ elanikkonna eluoluküsitluse teaduskoordinaatori Luule Sakkeusega eakate olukorrast Eestis

  13. Tallinn sõdib kahanevate tulude vastu uute maksude kehtestamisega / Urmas Tooming, Urmas Seaver ; kommenteerinud Indrek Raudne, Remo Holsmer

    Tooming, Urmas, 1954-

    2009-01-01

    Kahanevate tuludega toimetulekuks kavatseb Tallinna linnavõim kehtestada 1. juulist müügimaksu ja paadimaksu, tõsta ühistranspordi piletihindu mittetallinlastele ning kaotada mitmed linna poolt makstavad toetused. Vt. samas: Paadimaks; Müügimaks

  14. Jüri Pihl usub, et sotsid suudavad Tallinna juhtimist muuta / Urmas Seaver ; kommenteerinud Remo Holsmer ja Indrek Raudne

    Seaver, Urmas, 1973-

    2009-01-01

    Sotsiaaldemokraatide juht Jüri Pihl ja Keskerakonna liider Edgar Savisaar allkirjastasid Tallinna juhtimise koalitsioonileppe. Vt. samas: Mõned olulisemad lubadused koalitsioonileppest Tallinna juhtimiseks 2009-2013

  15. Kas seadus tõesti seljatab terve talupojamõistuse? / Aive Sarjas ; kommenteerinud Karina Loi, Andres Heinver

    Sarjas, Aive

    2009-01-01

    Kuusalu vallas toimuvad kord nädalas kaubavahetuspäevad "Otse tootjalt tarbijale", millega on rahul nii tootjad kui ka ostjad. Veterinaar- ja Toiduamet peab seda aga seadusevastaseks, kui müüjad pole maksnud riigilõivu ja taotlenud vastavat tunnustust

  16. Aasta vabatahtlik Kaija Kõiv pühendub noortele / Marge Väikenurm ; kommenteerinud Kaidi Helleng, Merle Tombak

    Väikenurm, Marge

    2009-01-01

    Tallinnas Õpetajate majas 6. detsembril 2009 toimunud vabatahtlike tunnustamisüritusel andis president Toomas Hendrik Ilves tänukirja ja vabatahtliku märgi 17-le aasta vabatahtlikule. Nende seas oli ka Kaija Kõiv, kes on Keeni avatud noortekeskuse juht ning õpib Tallinna Ülikoolis kunstiteraapiat. Kaija Kõiv viibis vabatahtlikuna Austrias Esperanzas, kus tegeles 13-17aastaste riskinoortega

  17. Ilona Gurjanova: Pooldan mõtteviisi learning by doing / Ilona Gurjanova ; intervjueerinud Kirke Kuld ; kommenteerinud Meelis Joost

    Gurjanova, Ilona, 1958-

    2016-01-01

    Intervjuu Design Management OÜ disaineri ja juhataja, Eesti Disainerite Liidu esimehe, Eesti Disaini Maja endise juhi ja Disainiöö peakorraldaja Ilona Gurjanovaga universaalsest disainist ja selle näidetest

  18. Eestlane tahab tasuta kvaliteetset arstiabi, järjekorras ootamata / Risto Sverdlik ; kommenteerinud Ain Aaviksoo, Eiki Nestor

    Sverdlik, Risto

    2009-01-01

    Autori hinnangul on Eesti tervishoiusüsteem sotsialistlik ning suhteliselt sarnase tervishoiusüsteemiga riikides on samad probleemid: ravijärjekorrad ja kulude kasv. Singapuri tervishoiumudelist. Autor leiab, et keskse planeerimisega tervishoiusüsteemi puhul kannatavad kõige rohkem vaesed, turumajanduslikus süsteemis aga ravihinnad järjest väheneksid

  19. Salapärased tarkusetabletid pole võõrad ka Eesti kooliõpilastele / Siiri Erala ; kommenteerinud Vince Cakic

    Erala, Siiri

    2009-01-01

    Akadeemilist võimekust parandavate ravimite kasutamisest USA kõrgkoolide õppurite seas. Meditsiiniajakiri British Medical Journal avaldas austraalia teadlase Vince Cakici artikli akadeemilisest dopingust. Tallinna Ülikooli terviseteaduste ja spordi instituudi direktori Kristjan Pordi teemakohased kommentaarid

  20. Laurentiuse kirik päästab Saueri oreli osi niiskuse käest / Andres Sepp ; kommenteerinud Anti Toplaan

    Sepp, Andres, 1976-

    2009-01-01

    Kuressaare Laurentiuse kiriku kogudus otsib võimalusi viia 1881. a. Wilhelm Saueri firmas valminud vanima Eestis säilinud oreli puidust ja metallist osad kuivemasse kohta. Praegu seisavad need kiriku garaažis

  1. Noorte suitsidaalne käitumine - ennetus, märkamine ja sekkumine / Merike Sisask ; kommenteerinud Anita Rõbkina

    Sisask, Merike, 1968-

    2015-01-01

    Kommentaaris Anita Rõbkina Tallinna Ülikooli Pedagoogilise Seminari noorsootöö eriala lõputööst, mille üks eesmärk oli uurida nootsootöötajate teadlikkust ja hinnanguid noorte suitsidaalse käitumise ennetamise võimalustest

  2. Tootest olulisemaks saab ärimudel. Kandiline arbuus tavalisest 30 korda kallim / Ain Alvela ; kommenteerinud Janek Kalvi

    Alvela, Ain, 1967-

    2011-01-01

    Eesti Arengufondi juhatuse esimehe Ott Pärna, ASi Kalev Chocolate Factory juhataja Kaido Kaare ja ASi Balsnack International Holding juhatuse esimehe Elmar Rusingu ettekannetest toiduainetööstuse aastakonverentsil "Uue tõusu ootuses". Graafik

  3. Ründo Mülts: "Vanemad on suunanud mind rahvuskultuuri austamise vaimus" / Raivo Raigna ; kommenteerinud Hanno Tamm, Priit Adler

    Raigna, Raivo

    2011-01-01

    Päinurme koduloomuuseumist, mille rajaja ja omanik on Ründo Mülts. Sel suvel valminud Ründo Mültsi filmist "Võhmuta mõis ja asundus aegade tuules". Tallinna Ülikooli ajalootudengina asus ta uurimisöö raames uurima antud piirkonna minevikku ning otsustas jäädvustada nähtu-kuuldu ka filmilindile

  4. Water Seri raskused partnerite kanda. Tõehetk sel nädalal / Alyona Stadnik ; kommenteerinud Tõnis Kurrik, Enno Heringson

    Stadnik, Alyona

    2011-01-01

    Sindi Vesi muutis kuu pärast riigihanke väljakuulutamist linna vee- ja kanalisatsioonitorustike hanke tingimust, täitmistagatise garantii tuleb esitada 28 päeva jooksul pärast lepingule allakirjutamist. Töid alustanud Water Ser Lääne-Eesti pole siiani garantiid esitanud. Vt. ka: Stadnik, Alyona. Water Ser esitas Sindi projektile garantiipaberi. Äripäev 26. mai, lk. 9

  5. SEB võis päästa oma raha investorite arvel / Piret Reiljan ; kommenteerinud Ahti Asmann

    Reiljan, Piret, 1983-

    2009-01-01

    SEB otsus maksta Toomas Rüütmanni TR Majade võlakirjainvestoritele hüvitist võib olla põhjustatud asjaolust, et SEB päästis Rüütmannile kuulunud Kommest Autost oma laenude katteks kümneid miljoneid kroone, mistõttu venitas TR Majade probleemidest teatamisega investoritele

  6. III sammas kiratseb edasi. Inimesed ei soovi sinna lisaraha panna / Katariina Krjutškova ; kommenteerinud Raivo Sormunen, Romet Kreek

    Krjutškova, Katariina

    2011-01-01

    III pensionisammaste mahud on võrreldes 2010. aastaga küll kasvanud, aga seda tänu fondide tootluse kasvule. SEB Varahalduse juhatuse liikme Sven Kunsingu, Swedbank Investeerimisfondide AS-i juhatuse esimehe Agnes Maki kommentaare

  7. Ehitame sotsiaalmaad täis elamuid, siis tulevad põlluelanikud linna? / Triin Talk ; kommenteerinud Endrik Mänd

    Talk, Triin

    2011-01-01

    Tallinna hipodroomi ala detailplaneeringust, millega tahetakse ala muuta korruselamute alaks. Tallinna üldplaneeringus on hipodroomi ala määratud ühiskondlike ja puhkeehitiste alaks, koostatavas rohealade teemaplaneeringus eriotstarbeliseks rohealaks

  8. Unustage töö ja eraelu tasakaal - seda pole olemas / Karen Schmidt ; kommenteerinud Adrian Furnham, Milvi Tepp

    Schmidt, Karen

    2014-01-01

    Viimaste uuringute kohaselt ei eksisteeri tänapäeva maailmas tasakaalu töö ja eraelu vahel, töö ja eraelu on põimunud - töööajal aetakse isiklikke asju, vaba aega kasutatakse töö tegemiseks. Üle-euroopalisest Samsungi töötajate uuringust

  9. Gild Bankersi töötajad tegid uue nõustamisfirma / Kadri Bank ; kommenteerinud Heikki Källu

    Bank, Kadri

    2010-01-01

    Gild Bankersi ettevõtete rahandusega tegelenud meeskond asutas grupivälise uue ettevõtte Gild IB OÜ. Seni sellega tegelev Gild Financial Advisory Services AS (Gild FAS) on esitanud finantsinspektsioonile investeerimisühingu tegevusloast loobumise taotluse

  10. Tubakamüüja süüdistab riiki kahju tekitamises / Kadrin Karner ; kommenteerinud Hille Reinhold

    Karner, Kadrin

    2010-01-01

    British American Tobacco Estonia ja Eesti Kaupmeeste Liit taotlesid riigilt vana maksumärgiga tubakatoodete müümistähtaja pikendamist kolmelt kuult kuuele. Kuna valitsus ettepanekut ei toetanud, leiab firma, et riik tekitas neile kahju 6,6 miljonit krooni

  11. Premia Foods avab börsil uue kasvutsükli / Kadri Jakobson, Kadri Bank ; kommenteerinud Andrus Alber

    Jakobson, Kadri, 1970-

    2010-01-01

    Premia Foods kavatseb oma aktsiad noteerida Tallinna börsil aprillis või mais, firma eesmärk on saada Baltimaade, Skandinaavia ja Loode-Venemaa juhtivaks sügavkülmutatud ja jahutatud toidukaupade tootmise ja müügiga tegelevaks ettevõtteks. Skeem: AS Premia Foods

  12. Uued CO₂ kasukad vanadele majadele / Elari Udam ; intervjueerinud Margit Mutso ; kommenteerinud Peeter Pere, Oliver Orro, Jaak Huimerind

    Udam, Elari, 1968-

    2011-01-01

    Vabade CO₂ kvootide müügist laekunud raha eest renoveeritakse energiatõhusaks 480 Eesti hoonet. Projekti juhib Riigi Kinnisvara AS. Teemat selgitab RKASi juhatuse liige ja haldusdirektor Elari Udam, kommenteerivad Eesti Arhitektide Liidu esimees Peeter Pere, aseesimees Jaak Huimerind ja arhitektuuriajaloolane Oliver Orro

  13. Austria uuringu tõlgendus: Eesti on eurotsooni must majandus / Kaja Koovit ; kommenteerinud Maria Alajõe

    Koovit, Kaja, 1968-

    2011-01-01

    Austrias asuva Linzi ülikooli uuringu kohaselt moodustab varimajandus Eesti majandusest kolmandiku. SSE Riga ehk Stockholmi majanduskooli Riias Balti varimajanduse uuringu põhjal võib varimajanduse osakaal Eestis olla 19,4 protsenti. Varimajanduse alal maailma juhtivaks eksperdiks peetava Friedrich Schneideri uuringust. Marje Josingu ja Juhan Partsi hinnanguid. Tabel: Varimajandus

  14. Aitab jumalateenistust paremini korraldada / Tiiu Pikkur ; kommenteerinud Tiit Salumäe, Jaak Salumäe, Arne Hiob

    Pikkur, Tiiu, 1947-

    2009-01-01

    17. märtsil peeti Tallinna Piiskoplikus Toomkirikus tänujumalateenistus, kus esitleti Eesti luterliku rahvakiriku esimese Eestimaal koostatud ja trükitud liturgiakäsiraamatu - neljaköitelise kirikukäsiraamatu kaht esimest osa: "Jumalateenistuste käsiraamatut" ja "Talituste käsiraamatut"

  15. Sanãtana dharma / René Guénon ; tõlkinud ja kommenteerinud Haljand Udam

    Guénon, René

    2004-01-01

    René Guénoni essee "Sanãtana dharma" ilmus 1949. a. ja uuesti 1989. a. raamatus "Études sur ľhindouisme" lk. 105-116 ja käsitleb mõiste "sanãtana dharma" ja "philosophia perennis" tõlgendusi ja tähendust. Esseele on lisatud põhjalik tõlkijapoolne kommentaar

  16. 800 ettevõtlusõpilast ootab rahvusvaheline eksam / Elbe Metsatalu ; kommenteerinud Marge Käis, Maris Lutsar

    Metsatalu, Elbe

    2016-01-01

    Õpilasfirmades ettevõtlusteadmisi ja -kogemusi omandavad õpilased saavad sooritada rahvusvahelise ettevõtluseksami. Edukalt läbinuile väljastab Junior Achievement Europe rahvusvahelise ettevõtlusteadmiste tunnistuse - Entrepreneurial Skill Pass’i

  17. Rein Ratase allkiri paneb rattad käima ; kommenteerinud Rein Ratas, Neeme Reinap, Vilmar Rei...[jt.

    Jakobson, Kadri, 1970-

    2010-01-01

    Riigikogu keskkonnakomisjoni liige Rein Ratas surub läbi firma EcoPro, mille üks omanik on Ratase hea tuttav, arendust Saaremaal Ruhve poolsaarel, mis asub kaitsealal ja ehituskeeluvööndis. Rein Ratas on tuludeklaratsioonis jätnud märkimata firmast Adepte Ekspert saadava tulu

  18. Thulema võlausaldajad kohtu armul / Anne Oja, Katariina Krjutškova ; kommenteerinud Jüri Ross

    Oja, Anne, 1970-

    2010-01-01

    Thulema ei suutnud saneerimiskava täita, firma endise juhi Tarmo Priki hinnangul oleks kavaga välja vedanud, kui uued omanikud poleks müügipersonali rohkem kui poole võrra vähendanud. Firma võlakohustused on 30. aprilli seisuga 40,2 mln., varade väärtus 38,9 mln. krooni

  19. Küttimine võib septembris peatuda. Maaomanikud vs. jahimehed / Ain Alvela ; kommenteerinud Heiki Hepner, Val Rajasaar

    Alvela, Ain, 1967-

    2011-01-01

    Maksumaksjad ja maaomanikud toetavad Eesti jahindust sisuliselt viie miljoni euroga aastas, kuigi keskkonnaspetsialistide hinnangul võiks asi olla vastupidi. Kehtiv jahiseadus ei aita kaasa metsa väärtuse parandamisele. Tabelid

  20. Mis tüüpi kodanikud on Eesti noored? / Veronika Kalmus, Mai Beilmann ; kommenteerinud Ilona-Evelyn Rannala

    Kalmus, Veronika, 1973-

    2017-01-01

    Eesti noorte ühiskondliku aktiivsuse tüpoloogiast. Kasutatud on projekti CATCH-EyoU raames 2016. a. lõpus korraldatud veebiküsitlusele vastanud 15-30aastaste noorte andmeid. Tallinna Ülikooli noorsootöö lektori Ilona-Evelyn Rannala kommentaar artikli kohta noorsootöö seisukohast

  1. Kas eestlastel on põhjust Bushi taga igatsema jääda? / Heiki Suurkask ; kommenteerinud Liisa Past

    Suurkask, Heiki, 1972-

    2009-01-01

    Hinnangutest USA presidendi George W. Bushi ametiajale. Autor leiab, et G. W. Bush ei ole olnud hiilgav, kuid ta pole olnud ka päris vilets riigipea. Aja jooksul on mõne USA presidendi maine paranenud. Kommenteerib Liisa Past

  2. Leis: aasta algus toob hinnatõusu. Balti turg kosub kriisist / Raivo Sormunen, Fredy-Edwin Esse ; kommenteerinud Kristo Oidermaa

    Sormunen, Raivo, 1976-

    2011-01-01

    Toorainehindade tõusu tõttu vähenes IV kvartalis Premia Foodsi kasumlikkus ning kallinevad I kvartalis toodete hinnad. Premia Foodsi 2010. a. brutokasumist andis 54% jäätis, ülejäänu jagunes külmkauba- ja kalasegmendi vahel

  3. Piimandus: laenukarid, ikaldused ja hinnaralli tõid kriisi / Ain Alvela ; kommenteerinud Tiit Tuuleveski, Urmas Põlluaas ja Tõnu Post

    Alvela, Ain, 1967-

    2009-01-01

    Kuigi piimatootmisega tegelevad ettevõtted vajaksid tegevuse arendamiseks hädasti investeeringuid, jäävad enamiku rahastamisplaanid paremaid aegu ootama. Diagramm. Kommenteerivad Tiit Tuuleveski, Urmas Põlluaas ja Tõnu Post

  4. Tootedisaineri töö peenmehaanika ja olemise jaatus / Ene Läkk

    Läkk, Ene, 1957-

    2011-01-01

    Tootjate ja riskikapitalistide huvist tootedisaineri teenuse vastu. Eesti disainibüroodest MaDis-Stuudio (Matti Õunapuu), Ten Twelve (asutaja: Jukka Halttunen), Keha3 (Margus Triibmann, Tarmo Luisk, Pavel Sidorenko, juht: Ville Jehe) ja Iseasi (Martin Pärn, Sven Sõrmus, Edina Dufala-Pärn, Pent Talvet, Kaspar Torn), pakutavatest teenustest ja töödest

  5. Eesti keele sõnavara afektikalduvus ja mis sellega peale hakata / Ene Vainik

    Vainik, Ene, 1964-

    2012-01-01

    Praktilisest vajadusest väljakasvanud probleemist muuta eestikeelne sünteeskõne loomulikumaks ja emotsionaalselt usutavamaks. Artiklis keskendutakse leksikaalsele tasandile, arutletakse selle üle, millised sõnaklassid on enim emotsioonidega seotud

  6. Otsusta Eesti Tulevik / Arnold Rüütel, Ene Ergma, Juhan Parts

    Rüütel, Arnold

    2003-01-01

    Ilmunud ka Valgamaalane (2003/Jun/28) lk. 2 ; Sakala (2003/Jun/27) lk. 2 ; Koit (2003/Jun/26) lk. 7 ; Maaleht (2003/Jun/26) lk. 4 ; Põhjarannik (2003/Jun/26) lk. 2 ; Severnoje Poberezhje (2003/Jun/26) lk. 2 ; Vooremaa (2003/Jun/26) lk. 1 ; Vaba Eesti Sõna (2003/Jul/2) lk. 3 ; Tribüün : Euroopa Liidu rahvahääletuse eri (2003/Aug/15) lk. 3. Vabariigi Presidendi, Riigikogu esimehe ja peaministri ühisavalduse tekst

  7. Kuressaare kultuurikeskus täitus eile leivalõhnaga / Ene Kallas

    Kallas, Ene

    2009-01-01

    Kuressaare kultuurikeskuse näituse "Leib on talu peremees" avamisel viisid Eesti Põllumajandusmuuseumi töötajad läbi leivaprogrammi. Näituse koostas Mare Viiralt, kunstnikutöö tegi Maarika Tang

  8. Learning Organizations. Studiu exploratoriu asupra Consiliilor Judeţene din România

    Diana GHIURA

    2012-12-01

    Full Text Available This article is the result of an ample study centered on the concept of learning organizations, more precisely on the degree in which Romanian County Councils are learning organizations. In order to analyze this, a research instrument has been sent to every County Council. This tool has been developed by three Harvard professors: David A. Garvin, Amy C. Edmondson and Francesca Gino who also published, in 2008, an article in Harvard Business Review ‘Is Yours A Learning Organization?’. Their article is fundamental for this study. Approximately 26 out of 41 County Councils participated to the study and the findings are summarized in this article. The results were really interesting and according to them, Romanian County Councils are learning organizations only in terms of leadership that encourages learning. Regarding the other two blocks – learning environment and learning processes, the findings revealed that the County Councils act like learning organizations in a very small degree. As a consequence, the organizations that participated to the study still have many things to improve in order to become learning organizations.

  9. Riigipeade kokad - Chefs des Chefs / Sirkka Ruottinen, Indrek Kivisalu ; interv. Ene Ojaveski

    Ruottinen, Sirkka

    2006-01-01

    Soome presidendi Tarja Haloneni ja Eesti presidendi Arnold Rüütli peakokad räägivad oma karjäärist presidendi peakoka ametini, kirjeldavad tavalist tööpäeva ja töökeskkonda presidendi köögis, iseloomustavad Soome ja Eesti toidukultuuri ning meenutavad huvitavaid seiku oma ametiajast. Vt. samas: Sirkka Ruottinen vastab küsimustele, mis puudutavad Riigipeade Peakokkade Klubi (Club des Chefs des Chefs) tegevust

  10. Emotsioonid eesti keele käeväljendites / Ene Vainik

    Vainik, Ene, 1964-

    2010-01-01

    Analüüsitakse eesti keele kõnelejate konventsionaalseid teadmisi ja ettekujutusi suhtlusprotsessist, uurides lähemalt leksikaalseid väljendeid, mille üheks komponendiks on viide käele (või selle osale)

  11. Tööjuhendid algklassi tööõpetuse tundides / Ene Lind

    Lind, Ene

    2001-01-01

    Tekstiga tööst tööõpetuse tunnis, kirjalikust ja suulisest juhendamisest. Tallinna Pedagoogikaülikooli üliõpilaste poolt läbi viidud küsitlusest, milles osalesid 22 klassiõpetajat Tallinnast ja 15 mujalt vabariigist. Kõik pedagoogid andsid oma klassis ka tööõpetuse või käsitöö tunde. Küsitlusega selgitati, milline on tööjuhendite abil korraldatava iseseisva individuaalse töö osatähtsus noorema kooliastme tööõpetuse ja eri õppeainete tundides

  12. How newness enters a country : reception of the "postcolonial" in Estonia / Ene-Reet Soovik

    Soovik, Ene-Reet, 1968-

    2006-01-01

    Postkolonialistliku tõlkekirjanduse retseptsiooni Eestis vaadeldakse kolme romaani põhjal: Arundhati Roy "Väikeste Asjade Jumal" (eesti k. 1997 ja 2004), Salman Rushdie "Mauri viimane ohe" (eesti k. 2001 ja 2008), Ben Okri "Näljutatud tee" (eesti k. 1998)

  13. Courants du Monde'i programmi toel Prantsusmaal / Asko Tamme ; intervjueerinud Ene Riet

    Tamme, Asko

    2010-01-01

    Intervjuu Tartu Linnaraamatukogu direktori Asko Tammega, kes käis tutvumas Prantsusmaa raamatukogudega, sh Pompidou keskuse raamatukoguga, Rennes'i keskraamatukoguga ning Raamatu ja Lugemise Bretagne'i keskusega (Livre et Lecture en Bretagne)

  14. Maakondliku Liivide etluskonkursi võitis gümnasist Marian Heinat / Ene Kallas

    Kallas, Ene

    2008-01-01

    Maakondliku Juhan ja Jakob Liivi etluskonkursi žüriisse kuulusid Ott Aardam, Käthe Pihlak, Piret Rauk, Vaido Luks ja Marili Pärtel. Grand prix' võitis Marian Heimat, laureaatideks tulid Liisa Saaremäel, Maria Pihlak ja Laura Oolup. Eripreemiad said Marii Metsmaa, Ermo Loik, Sander Aavik, Kaimar Nuut ja Priidu Aardam

  15. Tammsaare, Kangro ja Vanapagan / Ilse Lehiste ; inglise k. tlk. Ene-Reet Soovik

    Lehiste, Ilse, 1922-2010

    2000-01-01

    Orig.: Tammsaare, Kangro and the Devil. Varem ilmunud: Baltic Literature and Linguistics. Ohio : Association for the Advancement of Baltic Studies, 1973. A. H. Tammsaare romaanist "Põrgupõhja uus Vanapagan" (1939) ning Bernard Kangro romaanist "Taeva võtmed" (1956)

  16. Õpetaja haridus, kooliharidus ja ühiskond / Ene-Silvia Sarv

    Sarv, Ene-Silvia, 1945-

    1999-01-01

    Rahvusvahelise Haridusentsüklopeedia tekstist ja Eesti õpetajakoolituse uuendamise kavadest inspireeritud mõtisklus. Teoreetilised teadmised, võimed, eeldused, mida peetakse õpetajale vajalikuks, on seotud haridusele omastatavate eesmärkidega

  17. Leila Pärtelpoeg / Leila Pärtelpoeg ; interv. Ene Ammer

    Pärtelpoeg, Leila, 1927-

    1998-01-01

    Leila pärtelpoeg oma elust, arengust ja loomingust. Õpingutest Tallinna Riiklikus Tarbekunstiinstituudis, õppejõududest. Stazheerimisest Ermitaazhis NSVL mööblitundja Tatjana Mihhailovna Sokolova juures

  18. Solvent Effects in Asymmetric Hetero Diels-Alder and Ene Reactions

    Johannsen, Mogens; Jørgensen, Karl Anker

    1996-01-01

    The use of polar solvents such as nitromethane or 2-nitropropane leads to a significant improvement of the catalytic properties of a cationic copper-Lewis acid in the hetero Diels-Alder reaction of alkyl glyoxylates with dienes; The scope of a newly developed copper(II)-bisoxazoline catalyst...... for the hetero Diels-Alder reaction is demonstrated by the reaction of different dienes with alkyl glyoxylates in nitroalkane solvents with the formation of the hetero Diels-Alder adduct in high enantiomeric excess as the major product. The synthetic application of the reaction is exemplified by an improved...

  19. Me suudame ajaga kaasas käia / interv. Ene Riet

    2003-01-01

    Eesti raamatukoguhoidjate VIII kongressi (9.-10. juuni 2002) delegaatitelt küsiti arvamust Eesti raamatukogunduse kohta, vastasid: Kalli Kuhi, Sirje Okapuu, Toomas Liivamägi, Sirje Lauring-Vaska, Helve Sreiberg, Irina Kruusla, Ädu Neemre, Tiit Margna, Valentina Brovina, Asko Tamme, Meeli Veskus

  20. Kütiorus on kõrvuti pronksiaeg ja postmodernism / Ene Läkk

    Läkk, Ene, 1957-

    2000-01-01

    Külaskäik Kütioru Avatud Ateljeesse. Peeter ja Leelo Lauritsa tegemistest ja plaanidest seoses ateljeega. Valminud on ateljeemaja ümberehitamise makett. Ehitusmaterjaliks savi. Nõustavad Tartu ökoinsenerid. Sügisel 1999 viibisid Kütiorus Vogue'i ajakirjanikud ja Londoni fotograaf Zanna, et teha Casa Vogue'ile illustreeritud Kütioru Avatud Ateljeed tutvustav lugu. 5 värvilist illustratsiooni