Combining the Suicide Intent Scale and the Karolinska Interpersonal Violence Scale in suicide risk assessments.

Science.gov (United States)

Stefansson, J; Nordström, P; Runeson, B; Åsberg, M; Jokinen, J

2015-09-23

High suicide intent, childhood trauma, and violent behavior are risk factors for suicide in suicide attempters. The aim of this study was to investigate whether the combined assessment of suicide intent and interpersonal violence would provide a better prediction of suicide risk than an assessment of only suicide intent or interpersonal violence. This is a cohort study involving 81 suicide attempters included in the study between 1993 and 1998. Patients were assessed with both the Suicide Intent Scale (SIS) and the Karolinska Interpersonal Violence Scale (KIVS). Through the unique personal identification number in Sweden, patients were linked to the Cause of Death Register maintained by the Swedish National Board of Health and Welfare. Suicides were ascertained from the death certificates. Seven of 14 patients who had died before April 2013 had committed suicide. The positive predictive value for the Suicide Intent Scale alone was 16.7 %, with a specificity of 52 % and an area under the curve of 0.74. A combined assessment with the KIVS gave higher specificity (63 %) and a positive predictive value of 18.8 % with an AUC of 0.83. Combined use of SIS and KIVS expressed interpersonal violence as an adult subscale gave a sensitivity of 83.3 %, a specificity of 80.3 %, and a positive predictive value of 26 % with an AUC of 0.85. The correlation between KIVS and SIS scores was not significant. Using both the the SIS and the KIVS combined may be better for predicting completed suicide than using them separately. The nonsignificant correlation between the scales indicates that they measure different components of suicide risk.

The Potency of Bixa orellana Seedcouts Extract’s as Antiimflamation Drug

Directory of Open Access Journals (Sweden)

Atina Hussaana

2012-12-01

Design and Method: This study was post test only control group design. Twenty four mice is selected randomly then divided into four groups, KI (extract 0.09 mg, K.II (extract 0.18 mg dose, K.III (aspirin 90 mg, and K.IV (CMCNa 0.125%. Oedema volume was measured before injection karagenin 1%, two, 2.5, three and four hours after injection karagenin. The mean reduction in inflammation were tested by one way anova and pos hoc LSD. Result: Greatest reduction in inflammation indicated by K.III (0.100 ml, then in K.II (0.067 ml, KI (0.072 ml, and lowest in K.IV (-0.017 ml. Differences in the reduction of inflammation significantly different between KI and K.II K.IV; and K.III whereas no significant difference was found between KI and K.III K.II. Conclusion: The extract of the outer seed coats of annatto (Bixa orellana L. have antiimflamantory activity in mice that was induced by karagenin 1% (Sains Medika, 4(2:134-141.

Standard test method for plane-strain (Chevron-Notch) fracture toughness of metallic materials

CERN Document Server

American Society for Testing and Materials. Philadelphia

1997-01-01

1.1 This test method covers the determination of plane-strain (chevron-notch) fracture toughnesses, KIv or KIvM, of metallic materials. Fracture toughness by this method is relative to a slowly advancing steady state crack initiated at a chevron-shaped notch, and propagating in a chevron-shaped ligament (Fig. 1). Some metallic materials, when tested by this method, exhibit a sporadic crack growth in which the crack front remains nearly stationary until a critical load is reached. The crack then becomes unstable and suddenly advances at high speed to the next arrest point. For these materials, this test method covers the determination of the plane-strain fracture toughness, KIvj or KIvM, relative to the crack at the points of instability. Note 1—One difference between this test method and Test Method E 399 (which measures KIc) is that Test Method E 399 centers attention on the start of crack extension from a fatigue precrack. This test method makes use of either a steady state slowly propagating crack, or a...

Linear Logistic Test Modeling with R

Science.gov (United States)

Baghaei, Purya; Kubinger, Klaus D.

2015-01-01

The present paper gives a general introduction to the linear logistic test model (Fischer, 1973), an extension of the Rasch model with linear constraints on item parameters, along with eRm (an R package to estimate different types of Rasch models; Mair, Hatzinger, & Mair, 2014) functions to estimate the model and interpret its parameters. The…

Book Review: Commemoration as Conflict: Space, Memory and Identity in Peace Processes

DEFF Research Database (Denmark)

McQuaid, Sara Dybris

2016-01-01

Book rewiew: Commemoration as Conflict: Space, Memory and Identity in Peace Processes / Sara McDowell and Maire Braniff Palgrave Macmillan, 2014, 224pp., ISBN 978-0-230-27375-7......Book rewiew: Commemoration as Conflict: Space, Memory and Identity in Peace Processes / Sara McDowell and Maire Braniff Palgrave Macmillan, 2014, 224pp., ISBN 978-0-230-27375-7...

Antidepressive and BDNF effects of enriched environment treatment across ages in mice lacking BDNF expression through promoter IV

Science.gov (United States)

Jha, S; Dong, B E; Xue, Y; Delotterie, D F; Vail, M G; Sakata, K

2016-01-01

Reduced promoter IV-driven expression of brain-derived neurotrophic factor (BDNF) is implicated in stress and major depression. We previously reported that defective promoter IV (KIV) caused depression-like behavior in young adult mice, which was reversed more effectively by enriched environment treatment (EET) than antidepressants. The effects of promoter IV-BDNF deficiency and EET over the life stages remain unknown. Since early-life development (ED) involves dynamic epigenetic processes, we hypothesized that EET during ED would provide maximum antidepressive effects that would persist later in life due to enhanced, long-lasting BDNF induction. We tested this hypothesis by determining EET effects across three life stages: ED (0–2 months), young adult (2–4 months), and old adult (12–14 months). KIV mice at all life stages showed depression-like behavior in the open-field and tail-suspension tests compared with wild-type mice. Two months of EET reduced depression-like behavior in ED and young adult, but not old adult mice, with the largest effect in ED KIV mice. This effect lasted for 1 month after discontinuance of EET only in ED mice. BDNF protein induction by EET in the hippocampus and frontal cortex was also the largest in ED mice and persisted only in the hippocampus of ED KIV mice after discontinuance of EET. No gender-specific effects were observed. The results suggest that defective promoter IV causes depression-like behavior, regardless of age and gender, and that EET during ED is particularly beneficial to individuals with promoter IV-BDNF deficiency, while additional treatment may be needed for older adults. PMID:27648918

Presidendi paljurääkiv vaikimine / Vello Helk

Index Scriptorium Estoniae

Helk, Vello, 1923-2014

2005-01-01

Artikli autori arvates ei ole Eesti riigikaitse seisukohalt õige, et president Arnold Rüütel ei soovi avalikustada Boris Jeltsini poolt augustiputshi ajal avaldatud Eesti jaoks planeeritud nukuvalitsuse juhti. Ilmunud ka Eesti Päevaleht = Estniska Dagbladet, 2005/Sep/15, lk. 4

Determinants of Social Entrepreneurial Intentions

DEFF Research Database (Denmark)

Hockerts, Kai

This paper tests the model proposed by Mair and Noboa (2006) who identify four antecedents which they suggest predict social entrepreneurial intentions and behavior. This study tests the Mair and Noboa model and extends it by including prior experience with social problems as an additional variable...... entrepreneurial behavior of master students such as evidenced in the number of electives selected which have a social entrepreneurial profile....

Devising an indicator to detect mid-term abortions in dairy cattle: a first step towards syndromic surveillance of abortive diseases.

Directory of Open Access Journals (Sweden)

Anne Bronner

Full Text Available Bovine abortion surveillance is essential for human and animal health because it plays an important role in the early warning of several diseases. Due to the limited sensitivity of traditional surveillance systems, there is a growing interest for the development of syndromic surveillance. Our objective was to assess whether, routinely collected, artificial insemination (AI data could be used, as part of a syndromic surveillance system, to devise an indicator of mid-term abortions in dairy cattle herds in France. A mid-term abortion incidence rate (MAIR was computed as the ratio of the number of mid-term abortions to the number of female-weeks at risk. A mid-term abortion was defined as a return-to-service (i.e., a new AI taking place 90 to 180 days after the previous AI. Weekly variations in the MAIR in heifers and parous cows were modeled with a time-dependent Poisson model at the département level (French administrative division during the period of 2004 to 2010. The usefulness of monitoring this indicator to detect a disease-related increase in mid-term abortions was evaluated using data from the 2007-2008 episode of bluetongue serotype 8 (BT8 in France. An increase in the MAIR was identified in heifers and parous cows in 47% (n = 24 and 71% (n = 39 of the departements. On average, the weekly MAIR among heifers increased by 3.8% (min-max: 0.02-57.9% when the mean number of BT8 cases that occurred in the previous 8 to 13 weeks increased by one. The weekly MAIR among parous cows increased by 1.4% (0.01-8.5% when the mean number of BT8 cases occurring in the previous 6 to 12 weeks increased by one. These results underline the potential of the MAIR to identify an increase in mid-term abortions and suggest that it is a good candidate for the implementation of a syndromic surveillance system for bovine abortions.

Devising an indicator to detect mid-term abortions in dairy cattle: a first step towards syndromic surveillance of abortive diseases.

Science.gov (United States)

Bronner, Anne; Morignat, Eric; Hénaux, Viviane; Madouasse, Aurélien; Gay, Emilie; Calavas, Didier

2015-01-01

Bovine abortion surveillance is essential for human and animal health because it plays an important role in the early warning of several diseases. Due to the limited sensitivity of traditional surveillance systems, there is a growing interest for the development of syndromic surveillance. Our objective was to assess whether, routinely collected, artificial insemination (AI) data could be used, as part of a syndromic surveillance system, to devise an indicator of mid-term abortions in dairy cattle herds in France. A mid-term abortion incidence rate (MAIR) was computed as the ratio of the number of mid-term abortions to the number of female-weeks at risk. A mid-term abortion was defined as a return-to-service (i.e., a new AI) taking place 90 to 180 days after the previous AI. Weekly variations in the MAIR in heifers and parous cows were modeled with a time-dependent Poisson model at the département level (French administrative division) during the period of 2004 to 2010. The usefulness of monitoring this indicator to detect a disease-related increase in mid-term abortions was evaluated using data from the 2007-2008 episode of bluetongue serotype 8 (BT8) in France. An increase in the MAIR was identified in heifers and parous cows in 47% (n = 24) and 71% (n = 39) of the departements. On average, the weekly MAIR among heifers increased by 3.8% (min-max: 0.02-57.9%) when the mean number of BT8 cases that occurred in the previous 8 to 13 weeks increased by one. The weekly MAIR among parous cows increased by 1.4% (0.01-8.5%) when the mean number of BT8 cases occurring in the previous 6 to 12 weeks increased by one. These results underline the potential of the MAIR to identify an increase in mid-term abortions and suggest that it is a good candidate for the implementation of a syndromic surveillance system for bovine abortions.

Diagnosis of diabetes diseases using an Artificial Immune Recognition System2 (AIRS2) with fuzzy K-nearest neighbor.

Science.gov (United States)

Chikh, Mohamed Amine; Saidi, Meryem; Settouti, Nesma

2012-10-01

The use of expert systems and artificial intelligence techniques in disease diagnosis has been increasing gradually. Artificial Immune Recognition System (AIRS) is one of the methods used in medical classification problems. AIRS2 is a more efficient version of the AIRS algorithm. In this paper, we used a modified AIRS2 called MAIRS2 where we replace the K- nearest neighbors algorithm with the fuzzy K-nearest neighbors to improve the diagnostic accuracy of diabetes diseases. The diabetes disease dataset used in our work is retrieved from UCI machine learning repository. The performances of the AIRS2 and MAIRS2 are evaluated regarding classification accuracy, sensitivity and specificity values. The highest classification accuracy obtained when applying the AIRS2 and MAIRS2 using 10-fold cross-validation was, respectively 82.69% and 89.10%.

Articulações intrapartidárias e desempenho eleitoral no Brasil

Directory of Open Access Journals (Sweden)

George Avelino

2012-12-01

Full Text Available Les partis politiques brésiliens sont-ils importants sur le plan électoral? Cet article se consacre à ce problème en analysant si l'élection d'un maire influence les résultats électoraux de son parti dans la même commune. Un Modèle de Régression Discontinue (RDD est utilisé pour identifier l'influence des maires sur les résultats électoraux de leur parti lors de l'élection de députés tant au niveau fédéral que de l'État. Les résultats obtenus suggèrent que l'élection d'un maire (même lorsque sa victoire n'est due qu'à 1% de différence devra augmenter les scores du même parti aux élections législatives, que ce soit sur le plan fédéral ou de l'état. Ce résultat est interprété comme une évidence de l'articulation interne des partis, les maires agissant systématiquement en faveur des candidats au poste de député fédéral de leur propre parti.

Farvel til partierne, goddag til nødvendigheden

DEFF Research Database (Denmark)

Celik, Tim Holst

2015-01-01

Teknokrati Peter Mair kortlægger i sin bog 'Ruling the Void' undermineringen af det vestlige partidemokrati. Gennem en opsummering af den empiriske forskning beskriver bogen fremkomsten og udviklingen af ' nødvendighedens politik' på det partipolitiske plan......Teknokrati Peter Mair kortlægger i sin bog 'Ruling the Void' undermineringen af det vestlige partidemokrati. Gennem en opsummering af den empiriske forskning beskriver bogen fremkomsten og udviklingen af ' nødvendighedens politik' på det partipolitiske plan...

Determinants of Social Entrepreneurial Intentions

DEFF Research Database (Denmark)

Hockerts, Kai

2017-01-01

This article tests the model proposed by Mair and Noboa (2006) who identify four antecedents which they suggest predict social entrepreneurial intentions. The study extends the model by including prior experience with social problems as an additional variable. Findings show that prior experience ...... social entrepreneurship electives students enroll in is predicted by social entrepreneurial intentions.......This article tests the model proposed by Mair and Noboa (2006) who identify four antecedents which they suggest predict social entrepreneurial intentions. The study extends the model by including prior experience with social problems as an additional variable. Findings show that prior experience...... predicts social entrepreneurial intentions. This effect is mediated by the antecedents suggested by Mair and Noboa. Social entrepreneurial self-efficacy has both the largest impact on intentions as well as being itself most responsive to prior experience. Lastly, the study shows that the amount of optional...

Tapa sõdurid aitasid Läti kamraade

Index Scriptorium Estoniae

2014-01-01

Lätis õppusel Summer Shield 2014 viibivad suurtükiväepataljoni ajateenijad korraldasid heategevusliku toetusjooksu, et koguda raha, toetamaks välisoperatsioonidel langenud Läti sõduritele monumendi püstitamist

Lack of promoter IV-driven BDNF transcription results in depression-like behavior.

Science.gov (United States)

Sakata, K; Jin, L; Jha, S

2010-10-01

Transcription of Bdnf is controlled by multiple promoters, in which promoter IV contributes significantly to activity-dependent Bdnf transcription. We have generated promoter IV mutant mice [brain-derived neurotrophic factor (BDNF)-KIV] in which promoter IV-driven expression of BDNF is selectively disrupted by inserting a green fluorescent protein (GFP)-STOP cassette within the Bdnf exon IV locus. BDNF-KIV animals exhibited depression-like behavior as shown by the tail suspension test (TST), sucrose preference test (SPT) and learned helplessness test (LHT). In addition, BDNF-KIV mice showed reduced activity in the open field test (OFT) and reduced food intake in the novelty-suppressed feeding test (NSFT). The mutant mice did not display anxiety-like behavior in the light and dark box test and elevated plus maze tests. Interestingly, the mutant mice showed defective response inhibition in the passive avoidance test (PAT) even though their learning ability was intact when measured with the active avoidance test (AAT). These results suggest that promoter IV-dependent BDNF expression plays a critical role in the control of mood-related behaviors. This is the first study that directly addressed the effects of endogenous promoter-driven expression of BDNF in depression-like behavior. © 2010 The Authors. Genes, Brain and Behavior © 2010 Blackwell Publishing Ltd and International Behavioural and Neural Genetics Society.

Antecedents of Social Entrepreneurial Intentions

DEFF Research Database (Denmark)

Hockerts, Kai

2013-01-01

This paper is a contribution towards Mair and Noboa ‘s (2006) model of the antecedents of social entrepreneurial intentions. The Mair/Noboa model builds on Krueger’s (1993) proposal of a theory of planned behavior for entrepreneurial intention formation by suggesting that social entrepreneurial...... intentions are driven by an individual’s perceived desirability and perceived feasibility of starting a social venture. This article proposes and validates measures of the antecedents of social entrepreneurial behavior with a sample of nascent social entrepreneurs. The measures developed adapt constructs...

Perspectieven in de robotica : Overzicht van samenwerkende disciplines

NARCIS (Netherlands)

Horne, C.; De Wolf, S.; Abd El Ghany, M.; Dumay, A.

1986-01-01

Symposium gehouden op 20 juni 1986 in het gebouw van de afdeling der Elektrotechniek, Technische Hogeschool Delft, georganiseerd door de IEEE Student Branch Delft, in samenwerking met IEEE Benelux Section NERG en KIvI

Tekstiil maalis / Maire Toom

Index Scriptorium Estoniae

Toom, Maire

1998-01-01

Tekstiili kujutamisest maalikunstis ja kunstnike - Jan Vermeer, Rembrandt, Jan van Eyck, Diego Vel{u00E1zquez, Raffael, Peter Paul Rubens, Tizian, Frans Hals, Eugène Delacroix, Henri Matisse, Pablo Picasso, Jaan Koort - loomingus.

1er mars 2017 - Signature du livre d'or, visite du tunnel du LHC au Point 5 et de la caverne expériementale de CMS par le Secrétaire d’Etat français aux Affaires européennes auprès du ministre des Affaires étrangères et du Développement international H. Désir.

CERN Multimedia

Bennett, Sophia Elizabeth

2017-01-01

Entourent le Secrétaire d'Etat pendant la signature du livre d'or: Le Préfet de l’Ain A. Cochet; le Directeur des accélérateurs et de la technologie F. Bordry; Ambassadeur, Représentant permanent de la France auprès de l’Office des Nations Unies à Genève et des Organisations internationales en Suisse E. Laurin; la Directrice générale du CERN F. Gianotti et la Directrice des relations internationales C. Warakaulle. Sont également présents: H. Bertrand, Maire de Saint-Genis-Pouilly; C. Bouvier, Maire de Cessy; G. Rousseau, Secrétaire Général de la sous-préfecture de Gex; Y. Mecibah, Directrice de Cabinet du Maire de Saint-Genis-Pouilly; F. Croquette, Ambassadeur pour les droits de l’homme, chargé de la dimension internationale de la Shoah, des spoliations et du devoir de mémoire; S. Bonbayl, Conseillère technique, Cabinet du Secrétaire d’Etat chargé des Affaires Européennes au MAEDI; F. Cormon-Veyssière, Sous-Directrice des droits de l’Homme et des Affaires humanitaires au MAEDI...

Hydroclimate of the Last Glacial Maximum and deglaciation in southern Australia's arid margin interpreted from speleothem records (23–15 ka

Directory of Open Access Journals (Sweden)

P. C. Treble

2017-06-01

Full Text Available Terrestrial data spanning the Last Glacial Maximum (LGM and deglaciation from the southern Australian region are sparse and limited to discontinuous sedimentological and geomorphological records with relatively large chronological uncertainties. This dearth of records has hindered a critical assessment of the role of the Southern Hemisphere mid-latitude westerly winds on the region's climate during this time period. In this study, two precisely dated speleothem records for Mairs Cave, Flinders Ranges, are presented, providing for the first time a detailed terrestrial hydroclimatic record for the southern Australian drylands during 23–15 ka. Recharge to Mairs Cave is interpreted from the speleothem record by the activation of growth, physical flood layering, and δ18O and δ13C minima. Periods of lowered recharge are indicated by 18O and 13C enrichment, primarily affecting δ18O, argued to be driven by evaporation of shallow soil/epikarst water in this water-limited environment. A hydrological driver is supported by calcite fabric changes. These include the presence of laminae, visible organic colloids, and occasional dissolution features, related to recharge, as well as the presence of sediment bands representing cave floor flooding. A shift to slower-growing, more compact calcite and an absence of lamination is interpreted to represent reduced recharge. The Mairs Cave record indicates that the Flinders Ranges were relatively wet during the LGM and early deglaciation, particularly over the interval 18.9–15.8 ka. This wetter phase ended abruptly with a shift to drier conditions at 15.8 ka. These findings are in agreement with the geomorphic archives for this region, as well as the timing of events in records from the broader Australasian region. The recharge phases identified in the Mairs Cave record are correlated with, but antiphase to, the position of the westerly winds interpreted from marine core MD03-2611, located 550 km south

Nõukogude anneksioon 1940. aasta Eesti ajakirjanduse kõverpeeglis / Meelis Saueauk

Index Scriptorium Estoniae

Saueauk, Meelis, 1971-

2010-01-01

Artikkel keskendub Nõukogude anneksiooni esimesele faasile, trükiväljaannete ülevõtmisega kaasnenud muutustele, sellele, kuidas ja kes manipuleerisid Eesti massikommunikatsioonivahenditega. Juunisündmustest Leedus ja Lätis. Vaikivast ajastust pärit traditsioonid kergendasid ajakirjanduse ümberkujundamist. Eesti valitsus oli enda kujundatud rahustamispoliitika kammitsais

Regulation of valine and. alpha. -ketoisocaproate metabolism in rat kidney mitochondria

Energy Technology Data Exchange (ETDEWEB)

Miller, R.H.; Harper, A.E. (Univ. of Wisconsin, Madison (USA))

1988-10-01

Activities of branched-chain amino acid (BCAA) aminotransferase (BCAT) and {alpha}-keto acid dehydrogenase (BCKD) were assayed in mitochondria isolated from kidneys of rats. Rates of transamination of valine and oxidation of keto acids {alpha}-ketoisocaproate (KIC) or {alpha}-ketoisovalerate (KIV) were estimated using radioactive tracers of the appropriate substrate from amounts of {sup 14}C-labeled products formed. Because of the high mitochondrial BCAT activity, an amino acceptor for BCAT, {alpha}-ketoglutarate ({alpha}-KG) or KIC, was added to the assay medium when valine was the substrate. Rates of valine transamination and subsequent oxidation of the KIV formed were determined with 0.5 mM {alpha}-KG as the amino acceptor; these rates were 5- to 50-fold those without added {alpha}-KG. Rates of CO{sub 2} evolution from valine also increased when KIC was present; however, with KIC concentrations above 0.2 mM, rates of CO{sub 2} evolution from valine declined although rates of transamination continued to rise. When 0.05 mM KIC was added to the assay medium, oxidation of KIC was suppressed by inclusion of valine or glutamate in the medium. When valine was present KIC was not oxidized preferentially, presumably because it was also serving as an amino acceptor for BCAT. These results indicate that as the supply of amino acceptor, {alpha}-KG or KIC, is increased in mitochondria not only is the rate of valine transamination stimulated but also the rate of oxidation of the KIV formed from valine. Thus the rate of oxidation of BCAA can be controlled by factors that influence the rate and direction of BCAA transamination and, thereby, the supply of substrate for BCKD.

Regulation of valine and α-ketoisocaproate metabolism in rat kidney mitochondria

International Nuclear Information System (INIS)

Miller, R.H.; Harper, A.E.

1988-01-01

Activities of branched-chain amino acid (BCAA) aminotransferase (BCAT) and α-keto acid dehydrogenase (BCKD) were assayed in mitochondria isolated from kidneys of rats. Rates of transamination of valine and oxidation of keto acids α-ketoisocaproate (KIC) or α-ketoisovalerate (KIV) were estimated using radioactive tracers of the appropriate substrate from amounts of 14 C-labeled products formed. Because of the high mitochondrial BCAT activity, an amino acceptor for BCAT, α-ketoglutarate (α-KG) or KIC, was added to the assay medium when valine was the substrate. Rates of valine transamination and subsequent oxidation of the KIV formed were determined with 0.5 mM α-KG as the amino acceptor; these rates were 5- to 50-fold those without added α-KG. Rates of CO 2 evolution from valine also increased when KIC was present; however, with KIC concentrations above 0.2 mM, rates of CO 2 evolution from valine declined although rates of transamination continued to rise. When 0.05 mM KIC was added to the assay medium, oxidation of KIC was suppressed by inclusion of valine or glutamate in the medium. When valine was present KIC was not oxidized preferentially, presumably because it was also serving as an amino acceptor for BCAT. These results indicate that as the supply of amino acceptor, α-KG or KIC, is increased in mitochondria not only is the rate of valine transamination stimulated but also the rate of oxidation of the KIV formed from valine. Thus the rate of oxidation of BCAA can be controlled by factors that influence the rate and direction of BCAA transamination and, thereby, the supply of substrate for BCKD

Kunstisild Lätti / Juta Kivimäe

Index Scriptorium Estoniae

Kivimäe, Juta, 1952-

2000-01-01

Riia Linna Kunstikoolis õppinud eesti kunstnike näitus "Kontakt - kontakts." Eesti Kunstimuuseumis. Koostaja Maire Toom. Eestlaste kunstikoolis õppimise ajal direktoriks Vilhelms Purvitis. Õpetajaid - Janis Rozentals, Janis Roberts Tilbergs

Hypothalamic pituitary thyroid axis and exposure to interpersonal violence in childhood among women with borderline personality disorder

Directory of Open Access Journals (Sweden)

Cave Sinai

2014-05-01

Full Text Available Background: A relationship between exposure to sexual violence and thyroid hormone alterations has been observed among women with posttraumatic stress disorder (PTSD. Women with borderline personality disorder (BPD report a high estimate of childhood trauma. Objective: The aim of the present study was to assess relationships between thyroid hormone measures and exposure to violence in childhood in women with BPD. Method: A total of 92 clinically euthyroid women with BPD (53% with comorbid PTSD diagnosis and at least two prior suicide attempts were assessed with the Karolinska Interpersonal Violence Scales (KIVS. The KIVS contains four subscales with concrete examples of exposure to violence and expressed violent behavior in childhood (aged 6–14 years and during adult life (15 years or older. Baseline thyroid function was evaluated by measuring plasma free and bound triiodothyronine (FT3 and T3, thyroxine (FT4 and T4, and thyroid-stimulating hormone (TSH with immunoassays. The FT3/FT4 ratio was used to estimate peripheral deiodination. Plasma cortisol was also assessed. Results: Sixty-seven percent of patients reported medium high or high level of exposure to interpersonal violence as a child. The FT3/FT4 ratio showed a significant negative correlation with exposure to violence as a child. Patients with PTSD had significantly higher plasma cortisol levels. An ad hoc analysis revealed that the correlation between KIVS exposure to interpersonal violence as a child and FT3/FT4 ratio was significant only in patients with comorbid PTSD. Altered thyroid activity, especially FT3/FT4, levels was associated with exposure to violence in childhood in women with BPD. Conclusion: Severe childhood trauma-related stress may promote lasting altered thyroid levels and/or contribute to the development of psychopathology associated with BPD traits or PTSD.

Paneeldiskussioon [veebipõhisest õpikeskkonnast] / Mart Laanpere

Index Scriptorium Estoniae

Laanpere, Mart

2003-01-01

Maire Salundi (projekt Learning for Sharing) juhtimisel läbi viidud paneeldiskussioon, milles osalesid Mart Laanepere, Kerttu Lõhmus (AS Trainator Training), Mall Maasik (Audentes Ariko AS) ja Anne Villems (Tartu Ülikool)

Shear Wave Generation from Overdriven Cavities in Rock

National Research Council Canada - National Science Library

Liu, Charles

2000-01-01

.... Maire carried out this work as part of his Phd) research. During the award period we began to explore ways to simplify the structure-based modeling so that it could be used in repetitive engineering calculations...

Structure-Based Turbulence Model

National Research Council Canada - National Science Library

Reynolds, W

2000-01-01

.... Maire carried out this work as part of his Phi) research. During the award period we began to explore ways to simplify the structure-based modeling so that it could be used in repetitive engineering calculations...

Pühaderoad terviseks / Eva Mere

Index Scriptorium Estoniae

Mere, Eva

1999-01-01

Kuidas peavad jõulupühi need, kes teistele söögitegemist õpetavad. Ajakirjade köögitoimetajad : Maire Suitsu Eesti Naisest, Kaie Mei Stiilist ja Tervisest, Angeelika Kang Kodukirjast, Lia Virkus Perest ja Kodust

Prishla pora otdat Viiraltu dolg / Rein Raamat ; interv. Nikolai Hrustaljov

Index Scriptorium Estoniae

Raamat, Rein, 1931-

2000-01-01

Endine joonisfilmide looja, praegune tõsielufilmide produtsent ja režissöör oma tööst, eriti kahest viimasest portreefilmist "Inimene, kes oskab olla õnnelik" ja "Maire Männik, 54 rue du Montparnasse"

Pallaslitaania : ka traditsioonilist skulptuuri tuleb aktiivselt eksponeerida / Eero Kangor

Index Scriptorium Estoniae

Kangor, Eero, 1982-

2006-01-01

Näitus "Pallase skulptuur" Tartu Kivisilla galeriis kuni 24. IX, kuraator Ahti Seppet. Enn Roosi, Maire-Helve Männiku, Ernst Jõesaare, Irmgard Luha, Eduard Wiiralti, Ferdi Sannamehe, Johannes Hirve ja August Vommi töödest

Baltika Moetänav = Baltika Fashion Street

Index Scriptorium Estoniae

2010-01-01

Tallinnas Veerenni 24 asuvast Baltika Moetänava sisearhitektuursest lahendusest. Autorid: Maire Milder, Ott Kangur, Ülo-Tarmo Stöör, Maris Kerge, Kaur-Lembit Stöör, Pärtel Eelma, Pekka Porkanen, Lauri Eltermaa

Mõtteid raamatust / Koost. Heigi Aaviste

Index Scriptorium Estoniae

1995-01-01

Aut.: Maire Liivamets, Paul Luhtein, Paul-Eerik Rummo, Maksim Gorki, Johannes Semper, R.Descartes, Valmar Adams, Lilli Promet, Paul Rummo, Cicero, Honoré de Balzac, Aleksandr Pushkin, Epikuros, Debora Vaarandi, Arvi Siig, Helene Johani, Juhan Smuul, Friedebert Tuglas

Social innovation and deliberative democracy

DEFF Research Database (Denmark)

Hulgård, Lars; Eschweiler, Jennifer

In much current literature on social entrepreneurship the entire focus is on the innovation and on the social value (the outcome) generated by the innovation. Social innovation is defined as “new and better ways to create social value” (Dees, 1998; 2002), or “social entrepreneurship seeks tipping...... points for innovation and change” (Light, 2008). In contrast to definitions that tentatively put the entire focus on the social value or end result without observing the process, Mair argues that the nature of social entrepreneurship “cannot be discussed without taking into consideration the complex set...... of institutional, social, economic and political factors” that make up the context of the social innovation (Mair, 2010: 26). Social innovation in its essence is a multidisciplinary phenomenon. Processes, practices and perceptions of social innovation tend to challenge not only the perception of state, market...

Absurd on igihaljas / Vaapo Vaher

Index Scriptorium Estoniae

Vaher, Vaapo, 1945-

2006-01-01

Tutvustus: Camus, Albert. Õnnelik surm / tõlkinud Tanel Lepsoo. Tallinn : Varrak, 2005 ; Metsanurk, Mait. Kreeps / koost. Maire Liivamets. Tallinn : Eesti Raamat, 2005. (Eesti novellivara). Järg: 23. veebr., lk. 27, sisaldab Aivar Kulli kriitikakogu "Kulli pilk" (Ilmamaa, 2005) tutvustust

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Directory of Open Access Journals (Sweden)

Redazione Reti Medievali (a cura di

2010-12-01

Full Text Available Peer reviewed by Renato Bordone, Filippo Burgarella, Sandro Carocci, Alexandra Chavarria Arnau, Simone Collavini, Salvatore Cosentino, Cristina La Rocca, Lech Leciejewicz, Jean-Claude Maire Vigueur, Marc Mayer, Eduardo Manzano Moreno, Fabio Saggioro, Chris Wickham, Enrico Zanini, Luca Zavagno.

Resonance – Journal of Science Education | Indian Academy of ...

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 14; Issue 8. Differential Scanning Calorimetry: Fundamental Overview. Kevin Lukas Peter K LeMaire. Classroom Volume 14 Issue 8 August 2009 pp 807-817. Fulltext. Click here to view fulltext PDF. Permanent link:

Extrathalamic Modulation of Cortical Responsiveness

Science.gov (United States)

1994-08-01

1988). McEntee, W. J. & Mair, R. G. (1990). The Korsakoff syndrome : a Clonidine improves memory function in schizophrenia indepen- neurochemical...cognition and putati% e neurotransmitters on neuronal activity in monkey auditory rCBF in Korsakoffs psychosis. Psychological Medicine (in the cortw. Brain

CineClub

CERN Multimedia

CineClub

2014-01-01

  In partnership with FIFOG, le Festival International du Film Oriental de Genève   Wednesday 16 April 2014 at 20:00 CERN Council Chamber Où est l’amour dans la palmeraie?        Directed by Jérome le Maire (Belgium, 2006) 87 minutes   Jérôme Le Maire quitte la Belgique avec sa famille et s’installe dans une palmeraie au Maroc. Dans cet univers traditionnel musulman, il tente de comprendre comment s’exprime l’amour et ce qu’il veut dire pour des villageois imperméables aux conceptions des Européens «libérés». Original version French/Arabic; English subtitles     Thursday 24 April 2014 at 20:00 CERN Council Chamber   4 Months, 3 Weeks and 2 Days   Directed by Cristian Mungiu (Romania, 2007) 113 minutes   Romania...

Jesus Cristo senhor e salvador da cidade: imaginário crente e utopia política

Directory of Open Access Journals (Sweden)

Clara Mafra

2006-01-01

Full Text Available Dans cet article, on retrouve un décret présenté par un maire obscur d'une ville de Rondônia (Brésil qui déclare Jésus Christ comme seul Seigneur et Sauveur de la ville, pour expliquer quelques tensions vécues dans un pays républicain qui vit un élargissement de sa vie démocratique. On prétend que le maire, ainsi que d'autres concitoyens, lorsqu'ils se servent des instruments d'exercice du pouvoir républicain, n'ont pas connaissance de la logique interne ni du développement historique de ces instruments. D'autre part, les néophytes s'approprient des instruments républicains animés par des sentiments flous et indéterminés, qui se traduisent par une imagination travaillée selon des aptitudes infuses.

Measuring the orbital angular momentum density for a superposition of Bessel beams

CSIR Research Space (South Africa)

Dudley, Angela L

2012-01-01

Full Text Available and amplitude gratings,? Opt. Commun. 284(1), 48?51 (2011). [8] Mair, A., Vaziri, A., Weihs, G., and Zeilinger, A., ?Entanglement of the orbital angular momentum states of photons,? Nature 412(6844), 313?316 (2001). [9] Gibson, G., Courtial, J., Padgett, M...

An FMRI Study of Olfactory Cues to Perception of Conspecific Stress

Science.gov (United States)

2010-04-01

Petrovic P, Ingvar M, Stone-Elander S, Petersson KM, Hansson P (1999) A PET activation study of dynamic mechanical allodynia in patients with...state on olfactory sensitivity suggest odor specificity. Biol Psychol 71: 244-247. 67. Mair RG, Bouffard JA, Engen T, Morton TH (1978) Olfactory

Oscaritel andsid tooni inimhinge süngete tungide filmid / Tiit Tuumalu

Index Scriptorium Estoniae

Tuumalu, Tiit, 1971-

2008-01-01

80. Oscarite galast. Joel ja Ethan Coeni mängufilm "Ei ole maad vanadele meestele" ("No Country for Old Men") võitis neli auhinda (parim film, režii, stsenaarium, meeskõrvalosa). Lisatud arvamused Timo Dienerilt,Tristan Priimägilt, Maire Aunastelt ja võitjate nimekiri

"Oskara" davali za filmõ o mratshnoi dushe / Tiit Tuumalu

Index Scriptorium Estoniae

Tuumalu, Tiit, 1971-

2008-01-01

80. Oscarite galast. Joel ja Ethan Coeni mängufilm "Ei ole maad vanadele meestele" ("No Country for Old Men") võitis neli auhinda (parim film, režii, stsenaarium, meeskõrvalosa). Lisatud arvamused Timo Dienerilt, Tristan Priimägilt, Maire Aunastelt ja võitjate nimekiri

The Importance of Loosely Systematized Game Phases in Sports: The Case of Attack Coverage Systems in High-Level Women’s Volleyball

Directory of Open Access Journals (Sweden)

Lorenzo Laporta

2015-03-01

Full Text Available Change is ubiquitous, but its degree and rate often affords detection of emerging patterns and establishing behavioral dynamics based on expected regularities. Match analysis capitalizes on such regularities, capturing information relevant for enhancing structure and reducing improvisation to a minimum. However, what if a game phase is only loosely regular, defying pattern systematization? Is it still possible to unfold principles of behavior capable of abstracting over-arching patterns? Our research focused on analysis of complex IV (KIV or attack coverage in volleyball. Fourteen matches from the 2013 Volleyball Women’s World Grand Champions Cup were analyzed. Results showed the occurrence of KIV corresponded to fewer than 5% of the total number of actions, and plays where a team successfully conquered a point after attack coverage was circa 1%, meaning this game complex will only make a difference in balanced matches. Overall, twenty-nine attack coverage structures emerged, denoting very high organizational variability. Attack coverage therefore provides an example of principle-based and not structured-based game phase. Associative analysis showed that quick attack tempos constrain the emergence of more complex attack coverage structures. The search for principle-based instead of structure-based game phases may provide useful insights for comprehension of game dynamics and for informing training processes.

Effect of Water Environment on Subcritical Crack Growth of Machinable Ceramics; Kaisakusei seramikkusu no kiretsu shinten tokusei ni oyobosu mizu kankyo no eikyo

Energy Technology Data Exchange (ETDEWEB)

Ikeda, K.; Kaizu, K.; Inotani, T. [Miyazaki Univ., Miyazaki (Japan); Yoshikawa, A.; Adachi, K.; Igaki, H. [Osaka Sangyo Univ., Osaka (Japan)

1997-06-15

The fatigue behavior of ceramics has been discussed on the basis of the relation between stress intensity facter (KI) and crack velocity (V). In this paper, the effect of environment on the relation between KI and V was studied on machinable ceramics (mica glass ceramics) and two kinds of glass ceramics with different grain sizes. The double torsion (DT) technique was used for the determination of the KI-V characteristics under different environments of air and ion-exchanged water. The characteristics of acoustic emission (AE) during stress corrosion cracking of mica glass ceramics was also examined. In water environment, the region II in the KI-V curve, in which crack velocity varies slowly with KI, disappeared. From this experimental fact, it was considered that at high KI, the crack velocity is encouraged by diffusion of the corrosive species to the crack and thus depended on the amount of water. SEM farc tography revealed that mica single crystals in the material caused crack arrest and deflection to occur. It is also found that AE event rate is quantitatively related to the crack velocity. AE measurement can be used in studying the crack propagation behavior of mica glass ceramics. 11 refs., 12 figs., 3 tabs.

See lihtne ja keeruline naivism / Maire Toom

Index Scriptorium Estoniae

Toom, Maire

2003-01-01

Kondase Keskusest, mille juhatajaks on Mari Vallikivi. Avanäitusel esitati Paul Kondase, Jaan Oadi, Venera Malinovskaja, Osvald Raba, Maks Raudsepa ja Boris Pau maale ning Joann Sõstra puunikerdusi. 7. maist näeb soome naivisti Kaija-Riitta Iivoneni töid

Lootuse festivalil osalesid lauljad Raplamaalt / Maire Kõrver

Index Scriptorium Estoniae

Kõrver, Maire, 1961-

2009-01-01

Tallinnas Saku Suurhallis 29.-31. maini toimunud evangeelsest üritusest - Lootuse festivalist, kus esinesid teiste seas lauljad Rapla Maarja- Magdaleena koguduse segakoorist, Hageri koguduse kammerkoorist Lambertus, Kohila babtistikoguduse segakoorist ja Märjamaa Maarja koguduse segakoorist Mariema

Raamatukogud kujundavad suhtumist / Maire Killar ; Priit Kasepalu

Index Scriptorium Estoniae

Killar, Maire

2009-01-01

Pimedate punktkirja looja Louis Braille 200. sünniaastapäeva tähistati ka Eestis. Eesti Pimedate Raamatukogus oli 26. septembrist 31. oktoobrini avatud näitus "Raamatud sõrmedele ja kõrvadele", Viljandi Linnaraamatukogus toimus 7. oktoobril nägemispuudega lugejate konverents

Alvar Aalto - 100 / Leila Pärtelpoeg

Index Scriptorium Estoniae

Pärtelpoeg, Leila, 1927-

1998-01-01

Villa Mairea'st, mis valmis 1939. a. ja mille A. Aalto projekteeris oma mõttekaaslastele ja sõpradele Harry ja Maire Gullichsenidele. Loetletud A. Aalto juubelit tähistavad rahvusvahelised näitused. Tallinna Kunstihoone galeriis 10.-11. 03 1998 näitus "Aalto mööbel"

Anneteparaad III / Karin Paulus

Index Scriptorium Estoniae

Paulus, Karin, 1975-

2008-01-01

Tutvustatakse Tartu Kõrgema Kunstikooli diplomandide lõputöid: 1. Diana Hints "Ba-Rokk", 2. Maire Rebina "Alleshoitud naeratused", 3. Liis Pihlik "Unistused ehk hingele pai", 4. Ille Agu "Pitsiring - pruudipesu kollektsioon", 5. Ingwald Koser "Chaise Longue", 6. Kaisa Paluoja installatsioon "/....../", 7. Kaidi Ploomipuu arvutiga juhitavatel telgedel kootud sisustuskangas

Strong anisotropy in the low temperature Compton profiles of ...

Indian Academy of Sciences (India)

Compton profiles of momentum distribution of conduction electrons in the orthorhombic phase of -Ga metal at low temperature are calculated in the band model for the three crystallographic directions (100), (010), and (001). Unlike the results at room temperature, previously reported by Lengeler, Lasser and Mair, the ...

Raua taltsutajad / Heigo Jelle ; interv. Anneliis Aunapuu

Index Scriptorium Estoniae

Jelle, Heigo, 1963-

1998-01-01

Unustatud sepatöö taas elluärkamisest. H. Jelle kaasaja sepa tööst, tellimustest, raua rollist ajaloos, heast maitsest sepatöös (Eesti sepatöö parimate näidetena toodud Maire Morgen-Hääle sepised), arhitektuuriga seotud ja iseseisvatest sepistest, materjali markidest, oma töödest.

77 FR 60731 - Notice of Applications for Deregistration Under Section 8(f) of the Investment Company Act of 1940

Science.gov (United States)

2012-10-04

.... [File No. 811-802]; Mairs & Power Balanced Fund Inc. [File No. 811-1048] Summary: Each applicant seeks... Parkway, Wilmington, DE 19809. ASGI Mesirow Insight TEI Fund I, LLC [File No. 811-22219]; ASGI Mesirow Insight Fund I, LLC [File No. 811-22220]; ASGI Mesirow Insight Fund A, LLC [File No. 811-22418]; ASGI...

Supporting Command and Control (C2) of an Embarked Commander: Tunneling SIPRNet Data Across an UNCLAS Wireless LAN

Science.gov (United States)

2011-09-01

that you did to help me through this process. Your efforts and guidance truly made this a success. To SPAWAR SCTD expert Stephanie Koontz , your...ty%20and%20Safety%20Services/05– 500%20Security%20Services/5510.36A.pdf [accessed June 19, 2011]. [28] S. Koontz . “Secret client tunneling...devices - KOV-26 talon user procedures.” Unpublished survey, SPAWAR, Point Loma, CA. [29] S. Koontz . “Secret client tunneling devices - KIV-54 user

Navy Network Dependability: Models, Metrics, and Tools

Science.gov (United States)

2010-01-01

surveillance; TCDL = Tactical Common Data Link; UHF = ultra high frequency; UFO = ultra-high-frequency follow-on; WGS = Wideband Gapfiller Satellite. RAND...VOICE (DMR VALUES) UFO OE-82 UHF LOS VOICE (DMR VALUES) UHF SATCOM VOICE DMR UHF LOS VOICE DMR TVs ADMS KIV-7 COMSEC ADNS SW ADNS II HW ISNS SW ISNS HW...Data Link; UHF = ultra high frequency; UFO = ultra-high-frequency follow-on; WGS = Wideband Gapfiller Satellite. RAND MG1003-1.1 4 Navy Network

Eesti esimesed naisskulptorid

Index Scriptorium Estoniae

2004-01-01

15. aprillist Adamson-Ericu muuseumis Juta Kivimäe koostatud näitus "Eesti esimesi naisskulptoreid". Näeb režissöör Rein Raamatu portreefilmi "Maire Männik, 54 Rue du Montparnasse" (2000). 12. V teabepäeval esinevad J. Kivimäe, Isabel Aaso, Mari-Liis Tammi, Reet Varblane, Rein Raamat

Leucopaxillus lepistoides, a new steppe fungus in Poland

Directory of Open Access Journals (Sweden)

Janusz Łuszczyński

2013-12-01

Full Text Available The paper presents information on Leucopaxillus lepistoides (Maire Singer, a new species for Poland. This fungus was found in two localities: the neighbourhood of Busko Zdrój and Chęciny (Little Polish Upland, S-Poland. Both localities were in the xerothermic grasslands belonging to the Cirsio-Brachypodion Order, Festuco-Brometea Class.

Taaskinnitati Raplamaa kui turvaliste paikkonna staatus / Maire Kõrver

Index Scriptorium Estoniae

Kõrver, Maire, 1961-

2009-01-01

Rapla maakond kuulub aastast 2004 ainsana Eestis rahvusvahelisse Safe Community ehk turvalise kodupaiga võrgustikku. Ülevaade Raplas toimunud Eesti II Safe Community konverentsist, kus tervitusega Riigikogust ja tunnustussõnadega Rapla maakonna tervisedendajatele esines parlamendi sotsiaalkomisjoni esimees Urmas Reinsalu

Teenuse ait-kuivati vajab kiiret tegutsemist / Maire Kõrver

Index Scriptorium Estoniae

Kõrver, Maire, 1961-

2009-01-01

Märjamaa vallale kuuluva arhitektuurimälestsena kaitse all oleva Teenuse mõisa ait-kuivati renoveerimise seisust. Hoone sai uued katuse aluskonstruktsioonid, kuid on katuseta. Taastamine on takerdunud seoses projektide rahastamisega

Läti avangardist Adamson-Ericu muuseumis / Maire Toom

Index Scriptorium Estoniae

Toom, Maire

2003-01-01

Läti kunstniku Ludolfs Libertsi (1895-1959) näitus "Maal ja teatrikunst" (17 maali, 7 teatrialast tööd) Adamson-Ericu muuseumis kuni 18. I 2004. 1937. a. Parisi maailmanäitusel pälvisid L. Libertsi lavakujundused grand prix' ja kuldmedali

Maakonnas tähistati advendiaja algust / Maire Kõrver

Index Scriptorium Estoniae

Kõrver, Maire, 1961-

2009-01-01

Advendiaja alguse tähistamisest Raplas, Märjamaal, Kuimetsas ja Kaius. Rapla kirikusse olid kogunenud advendituld süütama Rapla kihelkonna valdade esindajad. Kontserdi andsid Rapla Muusikakooli õpilased. Kuimetsas ja Kaius laulis kogunenud rahvale Margus Mikomägi

Täiskuu tervitas luulefestivali / Inge Põlma, Maire Kõrver

Index Scriptorium Estoniae

Põlma, Inge

2008-01-01

Ülevaade Täiskuu luulefestivalist, kus esinesid Kristiina Ehin, Andres Ehin, Ly Ehin, Contra, Sujata Bhatt, Ban'ya Natsuishi, Meelika Hainsoo, Lise Sinclair, Jaak Johanson, Lauri Õunapuu, Maria Peterson, Siiri Sisask, Kauksi Ülle, Sayumi Kamakura

184 Estimation des changements de la ligne de rivage de la zone ...

African Journals Online (AJOL)

youness

Estimation des changements de la ligne de rivage de la zone côtière sablonneuse de Kénitra au Maroc. Mohamed AHIZOUN1*, Eric MAIRE2, Souad HAIDA1,. José DARROZES2 et Jean-Luc PROBST3. 1 Laboratoire géophysique, mécanique des fluides, environnement et ingénierie mathématique - Equipe de recherche ...

Agrocybe putaminum (Agaricales, Basidiomycota, New for Poland

Directory of Open Access Journals (Sweden)

Halama Marek

2016-12-01

Full Text Available Agrocybe putaminum (Maire Singer, a species hitherto unknown in Poland, is reported from two localities in the southwestern part of the country, with descriptions and illustrations of the morphological characters of the newly collected basidiomata. The delimitation of A. putaminum is briefly discussed, and information on the ecology of the fungus and its world distribution is provided.

Jan Dullaert of Ghent on the Foundations of Propositional Logic

Czech Academy of Sciences Publication Activity Database

Hanke, Miroslav

2017-01-01

Roč. 55, č. 4 (2017), s. 273-306 ISSN 0042-7543 R&D Projects: GA ČR GB14-37038G Institutional support: RVO:67985955 Keywords : Jan Dullaert of Ghent * the circle of John Mair * scholastic logic * propositional logic * Bradwardine’s principle * infinite expressions Subject RIV: AA - Philosophy ; Religion OBOR OECD: Philosophy, History and Philosophy of science and technology

Determination of viscous pressure losssand resistance upstream from the choke point from breathing gases of different physical properties

DEFF Research Database (Denmark)

Pedersen, O.F.

2007-01-01

/mair)2- a  (JAP 48:313-319,1980), where r is gas  density and  m  is viscosity. a is an exponent  = 1 for laminar flow and  2 for turbulent flow MATERIAL AND METHOD: Nine healthy males , mean age (sd) = 32 (10) years examined in a pressure corrected flow body-plethysmograph, with measurement of maximum...

CSF 5-HIAA and exposure to and expression of interpersonal violence in suicide attempters.

Science.gov (United States)

Moberg, T; Nordström, P; Forslund, K; Kristiansson, M; Asberg, M; Jokinen, J

2011-07-01

Serotonin is implicated in impaired impulse control, aggression and suicidal behaviour. Low cerebrospinal fluid (CSF) concentrations of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA) have been found in violent suicide attempters, suicide victims and in violent offenders. CSF 5-HIAA concentrations have both genetic and environmental determinants. Childhood trauma may have an effect on central monoamine function as an adult. The aim of this study was to assess the relationship of CSF 5-HIAA and the exposure to and the expression of violence in childhood and during adult life measured with the Karolinska Interpersonal Violence Scale (KIVS). 42 medication free suicide attempters underwent lumbar puncture and were assessed with the Karolinska Interpersonal Violence Scale (KIVS) to assess history of childhood exposure to violence and lifetime expressed violent behaviour. In women, but not in men, CSF 5-HIAA showed a significant negative correlation to exposure to violence during childhood. Furthermore, suicide attempters with low CSF 5-HIAA were more prone to commit violent acts as an adult if exposed to violence as a child compared to suicide attempters with high CSF 5-HIAA. In the non-traumatized group, CSF 5-HIAA showed a significant negative correlation to expressed violent behaviour in childhood. Although central serotonergic function has important genetic determinants, exposure to childhood trauma may also affect serotonergic function. Low serotonergic function may facilitate impaired aggression control in traumatized suicide attempters. Copyright © 2011 Elsevier B.V. All rights reserved.

Elevated lipoprotein(a) and risk of aortic valve stenosis in the general population

DEFF Research Database (Denmark)

Kamstrup, Pia R; Tybjærg-Hansen, Anne; Nordestgaard, Børge G

2014-01-01

OBJECTIVES: The purpose of this study was to determine whether elevated lipoprotein(a) levels and corresponding LPA risk genotypes (rs10455872, rs3798220, kringle IV type 2 repeat polymorphism) prospectively associate with increased risk of aortic valve stenosis (AVS). BACKGROUND: The etiologic...... to 90 mg/dl), and 2.9 (95% CI: 1.8 to 4.9) for levels greater than 95th percentile (>90 mg/dl), versus levels less than the 22nd percentile (rs3798220 minor alleles, and of low number of KIV-2 repeats (trend, all p...

Air & Space Power Journal. Volume 27, Number 4, July-August 2013

Science.gov (United States)

2013-08-01

P-51 serves as an archetype of this era. With advances in sen - sors, beyond-visual-range combat grew in importance, and the critical skill set became...and Frances Mair, “Telesurgery versus Telemedicine in Surgery—an Overview,” Surgical Technology International 12 (February 2004): 68–72. 23. Amartya ... Sen , Commodities and Capabilities (Oxford, UK: Oxford University Press, 1999). 24. David A. Mindell, Between Human and Machine: Feedback, Control, and

Kaks kodu ühe katuse all / Ado Eigi

Index Scriptorium Estoniae

Eigi, Ado, 1938-2008

1998-01-01

Arhitekt Maire Annuse projekteeritud, 1997. a. valminud kahekorruseline kellerdatud kaksikelamu, mille keskel on kaht poolt siduva lülina avatud trepihallid. Kummagi elamupoole keskele on projekteeritud kolme korrust läbiv santehniliste ruumide blokk. Avarast kaminaga elutoast avaneb pääs terrassile ja aeda. Keldrikorrusel on puhkeruum, saun, väike bassein. Teisel korrusel on tütarde ja vanemate toad. Tütarde tubade kardinate autor - Kati Sihver

The Impact of Anti-Immigration Parties on Mainstream Parties' Immigration Positions in the Netherlands, Flanders and the UK 1987-2010: Divided electorates, left-right politics and the pull towards restrictionism

OpenAIRE

DAVIS, Amber

2012-01-01

Defence date: 20 April 2012; Examining Board: Professor Rainer Bauböck, EUI, for Professor Peter Mair (†), EUI (supervisor); Professor Virginie Guiraudon, National Center for Scientific Research, Paris; Professor Meindert Fennema, Universiteit van Amsterdam; Professor Dirk Jacobs, Université Libre de Bruxelles The rise of anti-immigration parties across Western Europe has put enormous pressure on mainstream parties to adapt their competitive strategies. This thesis tests the hypothesis tha...

Baltika kvartal = Baltika Quarter / Maris Kerge, Kadri Kerge

Index Scriptorium Estoniae

Kerge, Maris

2010-01-01

Rekonstrueeritud Baltika tööstushoonest: Moetänavast ja AS Baltika büroodest. Projekteerija, sisearhitektuur büroode osas: Studio 3 (4 arhitekti), büroo Kolm Pluss Üks (9 arhitekti). Sisearhitektuur Moetänava osas: Pekka Porkanen, Maris Kerge, Ott Kangur, Maire Milder, Lembit-Kaur Stöör, Ülo-Tarmo Stöör, Lauri Eltermaa, Pärtel Eelma. Projekt: 2007-2009, valmis: 2009

Perioperative epidural or intravenous ketamine does not improve the effectiveness of thoracic epidural analgesia for acute and chronic pain after thoracotomy.

Science.gov (United States)

Tena, Beatriz; Gomar, Carmen; Rios, Jose

2014-06-01

Persistent postsurgical pain (PPP) after thoracotomy effect 50% to 80%. Nerve damage and central sensitization involving NDMDAr activation may play an important role. This study evaluates the efficacy of adding intravenous (IV) or epidural ketamine to thoracic epidural analgesia (TEA) after thoracotomy. Double-blind randomized study on patients undergoing thoracotomy allocated to one of the following: group Kiv (IV racemic ketamine 0.5 mg/kg preincisional +0.25 mg/kg/h for 48 h), group Kep (epidural racemic ketamine 0.5 mg/kg preincisional +0.25 mg/kg/h for 48 h), or group S (saline). Postoperative analgesia was ensured by TEA with ropivacaine and fentanyl. Pain visual analog scales (VAS), Neuropathic Pain Symptom Inventory, Catastrophizing Scale, and Quantitative Sensory Testing, measuring both the peri-incisional and distant hyperalgesia area, were conducted preoperatively and postoperatively until 6 months. Plasma ketamine levels and stability of the analgesic solutions were analyzed. A total of 104 patients were included. PPP incidence was 20% at 6 months. Pain scores on coughing were significantly lower in Kiv and Kep than in S at 24 and 72 hours, but there were no differences afterwards. There were no significant differences in pain at rest, Neuropathic Pain Symptom Inventory, and Catastrophizing Scale, or in the area of mechanical allodynia at any time. Adverse effects were mild. Plasma ketamine levels did not differ significantly between groups. Analgesic solutions were stable. Adding epidural or IV racemic ketamine to TEA after thoracotomy did not lead to any reduction in PPP or allodynia. Epidural administration produced similar plasma ketamine levels to the IV route.

30 July 2012 - Prime Minister of France, Mr. Jean-Marc Ayrault, visits CERN

CERN Multimedia

Maximillien Brice

2012-01-01

Ligne d'accueil: Directeur général, R. Heuer présente: Directeur S. Myers, Chef des Relations internationales F. Pauss et Chefs de Département P. Bloch et A.-S. Catherin ; Représentants du CEA et du CNRS des 4 experiences LHC : J.-L. Faure, L. Fayard, C. Guyot, M.-H. Schune, Y. Schutz, Y. Sirois, Protocole CERN S. Molinari. Les autorités locales saluent le Premier ministre: M. Christophe Bouvier, maire de Cessy, M. Rachel Mazuir, sénateur de l'Ain, président du CG01, M. Etienne Blanc, député de l'Ain, maire de Divonne les Bains, et Mme Yvette Brachet, conseillère régionale représentant M. Jean-Jack Queyranne, président du CR Rhône Alpes. CERN-GE-1207163 32: dans le tunnel du LHC au Point 5: R. Garoby, Chef adjoint du département Faisceaux P. Lebrunm, Attaché à la Direction P. Bloch, Chef du département Physique J. Bertrand, (représente Alain Fuchs),CNRS Y. Sirois, Collaboration CMS, Responsable pour la France, Directeur de Recherche au CNRS, LLR Ecole Polytechnique J.-Y. Le Deaut, Dépu...

ÉTUDE DE CAS — Sénégal : Des données au service de la ...

International Development Research Centre (IDRC) Digital Library (Canada)

20 déc. 2010 ... Mais depuis, les enquêtes menées dans la commune, l'adoption d'un système de suivi communautaire de la pauvreté et la création d'un observatoire des conditions de vie ont changé la donne, et les citoyens en bénéficient. Apportez votre clé USB si vous avez rendez-vous avec El Hadj Malick Diop, maire ...

Diagnosis of Diabetes Diseases Using an Artificial Immune Recognition System2 (AIRS2) with Fuzzy K-nearest Neighbor

OpenAIRE

CHIKH, Mohamed Amine; SAIDI, Meryem; SETTOUTI, Nesma

2012-01-01

The use of expert systems and artificial intelligence techniques in disease diagnosis has been increasing gradually. Artificial Immune Recognition System (AIRS) is one of the methods used in medical classification problems. AIRS2 is a more efficient version of the AIRS algorithm. In this paper, we used a modified AIRS2 called MAIRS2 where we replace the K- nearest neighbors algorithm with the fuzzy K-nearest neighbors to improve the diagnostic accuracy of diabetes diseases. The diabetes disea...

Social entrepreneurship and social networks

OpenAIRE

Dufays, Frédéric

2013-01-01

In this presentation, we argue that the sociology of social networks may provide interesting insights with regard to the emergence of social entrepreneurship both at micro and macro levels. There have already been several calls for research on social networks in the context of social entrepreneurship (Certo & Miller 2008; Gedajlovic, et al. 2013; Haugh 2007; Mair & Marti 2006; Short, et al. 2009). These calls often address the differences in structure and effects of social networks in a socia...

Intoxication with natural sources

International Nuclear Information System (INIS)

Toropilova, D.; Toropila, M.; Tomko, M.; Takac, L.; Fric, M.

2015-01-01

The authors of this article deal with intoxication of the organism with natural resources. As objects of our interest we chose some interchangeable types of fungi which cause severe intoxication of gastrointestinal tract: Scleroderma citrinum, Boletus luridus var. rubriceps (Maire) Dermek, Boletus satanas, Agaricus xanthodermus and poisonous plants affect mainly digestive tract such as Sambucus nigra L. (elderberry). Sambucus ebulus L. (European dwarf elder), Viburnum lantana L. (wayfaring tree), Viburnum opulus (guelder-rose), Rhamnus cathartica (purging buckthorn).

Thermal Mapper (TMAP) concept to study volcanism on Io

OpenAIRE

Maturilli, A.; Helbert, J.; Walter, Ingo; Peter, Gisbert

2016-01-01

Thermal Mapper (TMAP) is part of the payload of the proposed Discovery mission IVO. TMAP will provide near-global coverage at 0.1–20 km/pixel to map heat flow and monitor volcanism. It is a high spatial- resolution thermal imaging system optimized for observing Io with heritage from the ESA AIDA mission’s Minaturized Asteroid infrared Imager (MAIR) and Radiometer instrument and the Bepi-Colombo mission’s MErcury Radiometer and Thermal Infrared Spectrometer (MERTIS). Minor modifications of the...

Magnesium Aluminum Borides as Explosive Materials

Science.gov (United States)

2011-12-20

pestle and screened -325 mesh to remove the filter paper. However, some of the filter paper remained in this powder. Table 13 Compositions of...Property of Si-B System Ceramics,” J. Japan Soc. Pow. and Pow. Met., 41[11] 1299-1303 (1994). 53. H. Nakamura, K. Murata, T. Anan, and Y. Hara...Oxidation of Zirconium Borides,” J. Japan Explosives Society, 55[4] 142-146 (1994). 54. M. Woerle, R.Nesper, G. Mair, M. Schwarz, and H. G. von Schnering

Physical current assets - accounting and reporting / Heidi Soe, Maire Nurmet

Index Scriptorium Estoniae

Soe, Heidi, 1941-

2003-01-01

Põllumajandusettevõtte majandustegevuses ja raamatupidamisarvestuses on oluline tähtsus käibevaral, sh materiaalsel käibevaral. Kasutatavast varade hindamise meetodist sõltub oluliselt nende mõju tootmishinnale ja kasumi kujunemisele. Tabelid

Õigusabi vähekindlustatuile / Mari Kasela ; kommenteerinud Maire Arm

Index Scriptorium Estoniae

Kasela, Mari

2011-01-01

Tasuta õigusabi majandus- ja makseraskustesse sattunud peredele pakub Eesti Juristide Liidu õigusportaal, esmase õigusabi teenust pakuvad Eesti Juristide Liit, sihtasutus Õigusteenuste Büroo Tallinnas, Üliõpilaste Õigusbüroo Tallinnas, Eesti Advokatuuri ja Lastekaitse Liidu koostööprojekt "Hea nõu lastega peredele"

Maydellide järeltulija teeb filmi oma juurtest / Maire Kõrver

Index Scriptorium Estoniae

Kõrver, Maire, 1961-

2009-01-01

Eestis, sh Raplamaal viibis Hollandis Haarlemi ülikoolis teletööd õppiv Maydellide järeltulija Sarah Albert, kes teeb koolitööna dokumentaalfilmi oma juurtest. Külaskäigust vanas mõisahoones asuvasse Maidla lastekodusse, Teenuse mõisa, Kullamaa kirikusse ja kalmistule ning Päri mõisa

Finantsinstrumendid ja nende arvestus Eesti hea raamatupidamistava alusel / Maire Otsus

Index Scriptorium Estoniae

Otsus-Carpenter, Maire, 1961-

2008-01-01

Finantsinstrumentide mõistest, sisust ja arvestuse põhimõtetest raamatupidamise seaduse ja Raamatupidamise Toimkonna juhendite põhjal. Lisatud: tuletisinstrumendid: forward, optsioon, swap, võlakiri ; näide 1: forwardleping ; näide 2: optsioon

Brain-derived neurotrophic factor signaling and subgenual anterior cingulate cortex dysfunction in major depressive disorder.

Science.gov (United States)

Tripp, Adam; Oh, Hyunjung; Guilloux, Jean-Philippe; Martinowich, Keri; Lewis, David A; Sibille, Etienne

2012-11-01

The subgenual anterior cingulate cortex is implicated in the pathology and treatment response of major depressive disorder. Low levels of brain-derived neurotrophic factor (BDNF) and reduced markers for GABA function, including in the amygdala, are reported in major depression, but their contribution to subgenual anterior cingulate cortex dysfunction is not known. Using polymerase chain reaction, we first assessed the degree to which BDNF controls mRNA expression (defined as BDNF dependency) of 15 genes relating to GABA and neuropeptide functions in the cingulate cortex of mice with reduced BDNF function (BDNF-heterozygous [Bdnf(+/-)] mice and BDNF exon-IV knockout [Bdnf(KIV)] mice). Gene expression was then quantified in the subgenual anterior cingulate cortex of 51 postmortem subjects with major depressive disorder and comparison subjects (total subjects, N=102; 49% were women) and compared with previous amygdala results. Based on the results in Bdnf(+/-) and Bdnf(KIV) mice, genes were sorted into high, intermediate, and no BDNF dependency sets. In postmortem human subjects with major depression, BDNF receptor (TRKB) expression, but not BDNF, was reduced. Postmortem depressed subjects exhibited down-regulation in genes with high and intermediate BDNF dependency, including markers of dendritic targeting interneurons (SST, NPY, and CORT) and a GABA synthesizing enzyme (GAD2). Changes extended to BDNF-independent genes (PVALB and GAD1). Changes were greater in men (potentially because of low baseline expression in women), displayed notable differences from prior amygdala results, and were not explained by demographic or clinical factors other than sex. These parallel human/mouse analyses provide direct (low TRKB) and indirect (low expression of BDNF-dependent genes) evidence in support of decreased BDNF signaling in the subgenual anterior cingulate cortex in individuals with major depressive disorder, implicate dendritic targeting GABA neurons and GABA synthesis

Growth of hatchery raised banana shrimp Penaeus merguiensis (de Man) (Crustacea: Decapoda) juveniles under different salinity

Digital Repository Service at National Institute of Oceanography (India)

Saldanha, C.M.; Achuthankutty, C.T.

relationships of estuaries to the fisheries of the Gulf of Mexico, in Estuaries, edited by Lauff G H (Amer Ass Adv Sci Publ, Washington D C) 1967, pp. 621-638. 3 Mair J McD, Salinity and water-type preference of four species of postlarval shrimp (Penaeus) from... west Mexico, J Exp Mar Biol Ecol, 45(1980)69-82. 4 Achuthankutty C T & Parulekar A H, Biology of commercially important penaeid prawns of Goa waters, Indian J Mar Sci, 15 (1986)171-173. 5 Achuthankutty C T & Parulekar A H, Distribution of penaeid...

Catholicisme et bourgeoisie. Retour sur les Origines de l'esprit bourgeois en France de Bernard Groethuysen

OpenAIRE

Maire, Catherine; Hours, Bernard

2008-01-01

Dans le cadre du GDR 2342 « l'esprit moderne en religion (xvie-xxe siècle) », le Centre d'anthropologie religieuse européenne (CARE) avec Catherine Maire et l'Institut d'histoire du christianisme avec Bernard Hours, ont organisé à Lyon, dans les locaux de l'université Jean-Moulin, une table ronde autour du livre de Bernard Groethuysen, Origines de l'esprit bourgeois en France (1927), avec la participation de Philippe Boutry, Louis Châtellier, François Chaubet, Marcel Gauchet, Alain Guéry, Ber...

Environmental issues and the common agricultural policy / Maire Nurmet, Heidi Soe

Index Scriptorium Estoniae

Nurmet, Maire, 1972-

2003-01-01

Keskkonnaprobleemid muutuvad üha aktuaalsemaks nii üldises plaanis kui ka maaelu arengu seisukohalt. Kuigi Eestis hetkel ei ole põllumajandusliku tegevuse tagajärjel tekkiv saastatus veel probleemiks, tuleks senisest rohkem tähelepanu pöörata keskkonna puhtuse säilitamisele

Tiina Gilli võluvad nii Ameerika kui ka Eesti / Maire Kõrvel

Index Scriptorium Estoniae

Kõrver, Maire, 1961-

2009-01-01

Fotograaf Tiina Gillist ja tema lennundusinstruktorist abikaasast James Frederick Gillist, kes elasid USA-s Seattle`is ning 2006. aastast elavad Märjamaa lähedal Rangu külas. James tegeleb maalimisega. Tiina on teinud looduse-, linna- ja lillepilte, vähem portreesid

Combining Task Execution and Background Knowledge for the Verification of Medical Guidelines

Science.gov (United States)

Hommersom, Arjen; Groot, Perry; Lucas, Peter; Balser, Michael; Schmitt, Jonathan

The use of a medical guideline can be seen as the execution of computational tasks, sequentially or in parallel, in the face of patient data. It has been shown that many of such guidelines can be represented as a 'network of tasks', i.e., as a number of steps that have a specific function or goal. To investigate the quality of such guidelines we propose a formalization of criteria for good practice medicine a guideline should comply to. We use this theory in conjunction with medical background knowledge to verify the quality of a guideline dealing with diabetes mellitus type 2 using the interactive theorem prover KIV. Verification using task execution and background knowledge is a novel approach to quality checking of medical guidelines.

Création d’un territoire olympique.

Directory of Open Access Journals (Sweden)

Benoît Montabone

2009-02-01

Full Text Available Carte extraite du site officiel de la candidature Pelvoux Écrins 2018. Le 23 septembre 2008, le milieu sportif français rigole : la ville de Gap n’est pas candidate pour accueillir les Jeux d’hiver « Gap 2018 ». A l’origine de cet imbroglio, un changement de municipalité au mois de mars précédent, et des conflits entre les acteurs principaux du projet, le maire de Gap et le promoteur d’une candidature « Alpes du Sud » pour accueillir les Jeux olympiques d’hiver en ...

Pique-nique à la plage.

Directory of Open Access Journals (Sweden)

Erwan Le Goff

2010-02-01

Full Text Available La plage, domaine public maritime placé sous l’autorité du maire est, a priori, un espace de liberté et d’égalité. Le pouvoir réglementaire de la commune peut cependant agir sur certaines pratiques spatiales, au cœur d’enjeux sociaux et politiques. La plage n’échappe pas à cette réglementation. L’estivant en quête d’un lieu agréable pour pique-niquer à Cabourg se dirigera volontiers vers la plage. La municipalité en a décidé autrement, comme le montre le panneau ...

L’apprentissage de la coopération intercommunale : modalités et instruments

OpenAIRE

Loubet, Lilian

2012-01-01

Le développement de l’intercommunalité donne lieu à des recompositions territoriales et gouvernementales majeures. Les élus se confrontent alors à l’exercice complexe de la coopération et à la définition d’un projet territorial. Il s’agira d’étudier la coopération intercommunale au regard des apprentissages (techniques, politiques et territoriaux) opérés par les maires et de concentrer l’analyse sur les « instruments » de ce processus. Ce propos est illustré par l’étude de l’agglomération tou...

National campaign - 100 collectivities connected to the green electric power

International Nuclear Information System (INIS)

2004-01-01

Since july 2004, the local collectivities, the little and medium enterprises and the craft workers can choose their electric power supplier. This offer can be a chance for the renewable energy. The association ''eco maires'' with the help of the WWF began a campaign to obtain the involvement of 100 collectivities interested by the green electric power. The project is presented. The authors presents also the new European Network on the green electric power, Eugene (European Green Electricity Network), which aims to harmonize criteria on the green electric power and to deliver certificates of quality. (A.L.B.)

The heuristic value of redundancy models of aging.

Science.gov (United States)

Boonekamp, Jelle J; Briga, Michael; Verhulst, Simon

2015-11-01

Molecular studies of aging aim to unravel the cause(s) of aging bottom-up, but linking these mechanisms to organismal level processes remains a challenge. We propose that complementary top-down data-directed modelling of organismal level empirical findings may contribute to developing these links. To this end, we explore the heuristic value of redundancy models of aging to develop a deeper insight into the mechanisms causing variation in senescence and lifespan. We start by showing (i) how different redundancy model parameters affect projected aging and mortality, and (ii) how variation in redundancy model parameters relates to variation in parameters of the Gompertz equation. Lifestyle changes or medical interventions during life can modify mortality rate, and we investigate (iii) how interventions that change specific redundancy parameters within the model affect subsequent mortality and actuarial senescence. Lastly, as an example of data-directed modelling and the insights that can be gained from this, (iv) we fit a redundancy model to mortality patterns observed by Mair et al. (2003; Science 301: 1731-1733) in Drosophila that were subjected to dietary restriction and temperature manipulations. Mair et al. found that dietary restriction instantaneously reduced mortality rate without affecting aging, while temperature manipulations had more transient effects on mortality rate and did affect aging. We show that after adjusting model parameters the redundancy model describes both effects well, and a comparison of the parameter values yields a deeper insight in the mechanisms causing these contrasting effects. We see replacement of the redundancy model parameters by more detailed sub-models of these parameters as a next step in linking demographic patterns to underlying molecular mechanisms. Copyright © 2015 Elsevier Inc. All rights reserved.

Tuuleenergia prognoosi täpsuse uuring / Teolan Tomson, Maire Hansen, Raimo Pirksaar

Index Scriptorium Estoniae

Tomson, Teolan, 1932-

2004-01-01

Esimene ekspluatatsioonikogemus näitas, et kohalikes oludes töötavad tuulikud (Virtsus) suhteliselt hästi. Väikesevõimsuselised tuulepargid ei mõjuta Eesti elektrivõrgu tööd, pigem vastupidi. Graafikud. Skeemid. Tabelid. Diagrammid

Theme and variations: The development of differences in Polynesian socio-political organizations

Directory of Open Access Journals (Sweden)

Martin A. van Bakel

2008-12-01

Full Text Available This article discusses the development of differences in the socio-political organization on the various Polynesian islands. Such differences were observed by early European visitors. Most of their descriptions date from the last quarter of the eighteenth century, but a few sources date back to the early seventeenth century, including the journals of the Dutch voyagers Schouten and Le Maire, Tasman, and somewhat later Roggeveen. The voyagers’ logs and journals often contain lengthy and detailed descriptions of the Polynesian peoples and cultures they encountered. And, though they often did not understand what they observed, they carefully described what they saw — or what they thought they saw.

éphémérides ou biographie sommaire de Savinien de Cyrano de Bergerac

Directory of Open Access Journals (Sweden)

Madeleine Alcover

2010-02-01

Full Text Available Biographie15519 avril : mariage, à Paris, des grands-parents paternels de l’écrivain, Savinien I de Cyrano et Anne Le Maire : celle-ci est la petite-fille d’Étienne Cardon, marchand parisien. À ce jour, l’origine du grand-père paternel n’est pas résolue (sarde ? descendant d’un marchand bourrelier de Sens ?.1555Le couple signe une donation entre vifs qui, en cas de décès, fait du survivant son légataire universel. Quatre enfants leur survivront : Abel, Samuel, Pierre et Anne.1555-1560Savinie...

La réservation de sièges dans les corps élus en Inde Reservation of Seats in Elected Bodies in India

Directory of Open Access Journals (Sweden)

David Annoussamy

2009-03-01

Full Text Available La Constitution de 1950 a prévu la réservation des sièges à la chambre basse fédérale et dans les assemblées législatives des Etats fédérés en faveur des castes répertoriées (anciens intouchables et des tribus répertoriées, proportionnellement à leur effectif dans la population totale. Ce procédé a eu pour effet d'éveiller et de développer la conscience politique de ces catégories qui ont maintenant des partis politiques à eux. Cependant la réservation qui avait été conçue comme une mesure provisoire devant durer 10 ans a été renouvelée tous les 10 ans, aucun parti politique n'osant s'y opposer de peur de perdre les voix de ces catégories de population.Cette réservation a été étendue aux sièges des conseils municipaux et aux postes de maires par une révision constitutionnelle de 1992. Mais son application a  soulevé des protestations sur le terrain, les gens de caste élevée ne voulant pas accepter comme maire un ancien intouchable.La même révision a réservé aux femmes 1/3 de postes de maires et de sièges dans les conseils municipaux. Pour l'instant les élues sont des prête-noms pour leur mari, père ou frère. Cela ne tire pas à conséquence dans les conseils mais les femmes sans aucune idée de l'administration catapultées au rôle de maire éprouvent des difficultés.Un projet de révision constitutionnelle  accordant la même réservation aux femmes à la chambre basse fédérale et dans les assemblées des Etats, élaborée en 1996 sur la recommandation  de Nations unies n'arrive pas à recueillir l'adhésion des partis politiques dominés par les hommes.The Constitution of India which came into force in 1950 provides for the reservation of seats in the lower house of the Union and the legislative assemblies of States in favour of Scheduled castes (ex -intouchables and Scheduled tribes proportionately to their number in the total population. That measure had the effect of arousing and

Le système de sûreté lyonnais selon les arrêtés du 6 décembre 1833

Directory of Open Access Journals (Sweden)

Amos Frappa

2010-01-01

Full Text Available Le 6 décembre 1833, le maire de Lyon Gabriel Prunelle adopte trois arrêtés instaurant un service de sûreté. Il s’agit de la seconde ville française à se doter d’un groupe de policiers spécialisé dans la recherche et l’arrestation des malfaiteurs. Un an plus tôt, le préfet de police Gisquet met à profit l’expérience de «  la Rousse », surnom donné à la brigade de l’ancien bagnard Vidocq, pour équiper la capitale d’une telle structure. Le premier des textes du 6 décembre 1833 fixe les attributi...

Formulation of the endophytic fungus Cladosporium oxysporum Berk.

Directory of Open Access Journals (Sweden)

Bensaci Oussama Ali

2015-01-01

Full Text Available Two formulations containing culture filtrates and conidial suspensions of the endophytic fungus Cladosporium oxysporum Berk. & M.A. Curtis, isolated previously from stems of Euphorbia bupleuroides subsp. luteola (Kralik Maire, were experimentally tested for their aphicid activity against the black bean aphid Aphis fabae Scop. found in Algeria. It was shown that invert emulsions are more effective against aphids, than using aqueous suspensions. This was especially true for formulations containing culture filtrates. The relatively insignificant mortalities obtained by formulations containing conidial suspensions indicated a low infectious potential towards the aphids. The proteolytic activity seemed to be more important than the chitinolytic activity of the fungus against the black bean aphid A. fabae

Les présidents chinois et suisse visitent le CERN

CERN Multimedia

CERN Press Office. Geneva

1999-01-01

Le vendredi 26 mars 1999, Jiang Zemin, Président de la République populaire de Chine, et Ruth Dreifuss, Présidente de la Confédération suisse, ont visité le Laboratoire européen pour la physique des particules, le CERN . Ils ont été accueillis par le Directeur général, Luciano Maiani, sur les lieux de l'expérience L3. En 1985, Jiang Zemin, alors maire de Shanghai, avait contribué à organiser la production de cristaux de BGO à l'Institut de céramique de Shanghai, cristaux qui jouent aujourd'hui un rôle essentiel dans l'expérience L3

Travaux et publications

OpenAIRE

M. Deville

2010-01-01

Ouvrages L'Oratoire à Angers aux xviie et xviiie siècles, Paris, 1975, 251 p. Le pouvoir municipal à Angers de 1657 à 1789, 2 vol., Angers, 1984, 293 et 348 p. Articles « La mission du père Honoré de Cannes à Angers en 1684 », Annales de Bretagne et des Pays de l'ouest (en abrégé ABPO dans les articles suivants), 1974, p. 501-516. « L'élection des maires d'Angers au xviiie siècle », Travaux sur le xviiie siècle, Angers, 1978, p 4-18. « Les messagers de l'université d'Angers dans la seconde mo...

Major histocompatibility complex (MHC) class III genetics in two Amerindian tribes from southern Brazil: the Kaingang and the Guarani.

Science.gov (United States)

Weg-Remers, S; Brenden, M; Schwarz, E; Witzel, K; Schneider, P M; Guerra, L K; Rehfeldt, I R; Lima, M T; Hartmann, D; Petzl-Erler, M L; de Messias, I J; Mauff, G

1997-10-01

Population genetic studies of the major histocompatibility complex (MHC) class III region, comprising C2, BF and C4 phenotypes, and molecular genetic data are rarely available for populations other than Caucasoids. We have investigated three Amerindian populations from Southern Brazil: 131 Kaingang from Ivaí (KIV), 111 Kaingang (KRC) and 100 Guarani (GRC) from Rio das Cobras. Extended MHC haplotypes were derived after standard C2, BF, C4 phenotyping and restriction fragment length polymorphism (RFLP) analysis with TaqI, together with HLA data published previously by segregation analysis. C2 and BF frequencies corresponded to other Amerindian populations. C4B*Q0 frequency was high in the GRC (0.429) but low in the Kaingang. Unusual C4 alleles were found, viz. C4A*58, A*55 and C4B*22 (presumably non-Amerindian) and aberrant C4A*3 of Amerindian origin occurring with a frequency of 0.223 in the GRC. C4A*3 bands of homo- and heterozygous individuals carrying this variant were Rodgers 1 positive and Chido 1,3 positive, showed a C4A specific lysis type and a C4A like alpha-chain. Polymerase chain reaction studies and sequencing showed that this is based on a C4A*3 duplication with a regular C4A*3 and a partially converted C4A*0304 carrying the C4B specific epitopes Ch 6 and Ch 1,3. Associations of class III haplotypes with particular RFLP patterns were similar to those reported for Caucasoids. The previously described association between combined C4A and CYP21P deletions and the 6.4 kb TaqI fragment was not seen in these Amerindians. This fragment occurred within a regular two locus gene structure in the Kaingang, representing a "short" gene at C4 locus I. C4 and CYP21 duplications were frequently observed. The distribution of extended MHC haplotypes provides evidence for a close relationship between the KIV and KRC and a larger genetic distance between the two Kaingang groups and the GRC.

Andres Ehin tähistas sünnipäeva raamatuesitlusega / Maire Kõrver

Index Scriptorium Estoniae

Kõrver, Maire, 1961-

2006-01-01

Andres Ehin esitles oma luulekogu "Põdrapõrnikapääsukene" ja selle ingliskeelset tõlget "Moose Beetle Swallow" oma sünnipäeval Iiri suursaadiku residentsis, kus oli kohal ka luulekogu tõlkija, Iiri luuletaja Patrick Cotter

RADIO ASTROMETRY OF THE CLOSE ACTIVE BINARY HR 5110

Energy Technology Data Exchange (ETDEWEB)

Abbuhl, E.; Mutel, R. L.; Lynch, C. [Department of Physics and Astronomy, University of Iowa, Van Allen Hall, Iowa City, Iowa 52242 (United States); Güedel, M. [Department of Astronomy, University of Vienna, Vienna (Austria)

2015-09-20

The close active binary HR 5110 was observed at six epochs over 26 days using a global very long baseline interferometry array at 15.4 GHz. We used phase referencing to determine the position of the radio centroid at each epoch with an uncertainty significantly smaller than the component separation. After correcting for proper motion and parallax, we find that the centroid locations of all six epochs have barycenter separations consistent with an emission source located on the KIV secondary, and not in an interaction region between the stars or on the F primary. We used a homogeneous power-law gyrosynchrotron emission model to reproduce the observed flux densities and fractional circular polarization. The resulting ranges of mean magnetic field strength and relativistic electron densities are of the order of 10 G and 10{sup 5} cm{sup −3}, respectively, in the source region.

Savoir lire les centres historiques comme clé pour construire la ville de demain

Directory of Open Access Journals (Sweden)

Alexis Sierra

2010-05-01

Full Text Available Yves Dauge est sénateur d’Indre et Loire (membre de la commission de la culture, de l'éducation et de la communication, membre du groupe d'études sur le patrimoine architectural. Inspecteur général de l’équipement, ancien maire de Chinon, il a été délégué interministériel à la ville et au développement social urbain de 1988 à 1991. Il a conduit la délégation française au Vème Forum Urbain Mondial à Rio. Il anime avec les services du Ministère des Affaires Etrangères et Européennes, le nouvea...

VizieR Online Data Catalog: JCMT Gould Belt Survey: Southern Orion A (Mairs+, 2016)

Science.gov (United States)

Mairs, S.; Johnstone, D.; Kirk, H.; Buckle, J.; Berry, D. S.; Broekhoven-Fiene, H.; Currie, M. J.; Fich, M.; Graves, S.; Hatchell, J.; Jenness, T.; Mottram, J. C.; Nutter, D.; Pattle, K.; Pineda, J. E.; Salji, C.; di, Francesco J.; Hogerheijde, M. R.; Ward-Thompson, D.; Bastien, P.; Bresnahan, D.; Butner, H.; Chen, M.; Chrysostomou, A.; Coude, S.; Davis, C. J.; Drabek-Maunder, E.; Duarte-Cabral, A.; Fiege, J.; Friberg, P.; Friesen, R.; Fuller, G. A.; Greaves, J.; Gregson, J.; Holland, W.; Joncas, G.; Kirk, J. M.; Knee, L. B. G.; Marsh, K.; Matthews, B. C.; Moriarty-Schieven, G.; Mowat, C.; Rawlings, J.; Richer, J.; Robertson, D.; Rosolowsky, E.; Rumble, D.; Sadavoy, S.; Thomas, H.; Tothill, N.; Viti, S.; White, G. J.; Wouterloot, J.; Yates, J.; Zhu, M.

2017-11-01

The observations presented throughout this paper were performed using the SCUBA-2 instrument (Holland et al., 2013MNRAS.430.2513H) as part of the JCMT Gould Belt Survey (Ward-Thompson et al., 2007PASP..119..855W). This instrument has provided continuum coverage at both 850um and 450um simultaneously at effective beam sizes of 14.1-arcsec and 9.6-arcsec, respectively (Dempsey et al., 2013MNRAS.430.2534D). In this work, we present Southern Orion A in both wavelengths, but focus mainly on the 850um data for analysis. All of the observations were taken in the PONG1800 mapping mode, yielding circular maps ('PONGs') of 0.5° in diameter. There are 17 0.5° subregions across the Orion A Molecular Cloud, 13 of which cover Southern Orion A. These locations were individually observed four to six times throughout 2012 February to 2015 January, and were then co-added (once co-added, these structures are referred to as 'tiles') and mosaicked to form the final map. (3 data files).

Climate Change Studies over Bangalore using Multi-source Remote Sensing Data and GIS

Science.gov (United States)

B, S.; Gouda, K. C.; Laxmikantha, B. P.; Bhat, N.

2014-12-01

Urbanization is a form of metropolitan growth that is a response to often bewildering sets of economic, social, and political forces and to the physical geography of an area. Some of the causes of the sprawl include - population growth, economy, patterns of infrastructure initiatives like the construction of roads and the provision of infrastructure using public money encouraging development. The direct implication of such urban sprawl is the change in land use and land cover of the region. In this study the long term climate data from multiple sources like NCEP reanalysis, IMD observations and various satellite derived products from MAIRS, IMD, ERSL and TRMM are considered and analyzed using the developed algorithms for the better understanding of the variability in the climate parameters over Bangalore. These products are further mathematically analyzed to arrive at desired results by extracting land surface temperature (LST), Potential evapo-transmission (PET), Rainfall, Humidity etc. Various satellites products are derived from NASA (National Aeronautics Space Agency), Indian meteorological satellites and global satellites are helpful in massive study of urban issues at global and regional scale. Climate change analysis is well studied by using either single source data such as Temperature or Rainfall from IMD (Indian Meteorological Department) or combined data products available as in case of MAIRS (Monsoon Asia Integrated Regional Scale) program to get rainfall at regional scale. Finally all the above said parameters are normalized and analyzed with the help of various open source available software's for pre and post processing our requirements to obtain desired results. A sample of analysis i.e. the Inter annual variability of annual averaged Temperature over Bangalore is presented in figure 1, which clearly shows the rising trend of the temperature (0.06oC/year). Also the Land use and land cover (LULC) analysis over Bangalore, Day light hours from

The Social Entrepreneurial Antecedents Scale (SEAS)

DEFF Research Database (Denmark)

Hockerts, Kai

2015-01-01

as to identify possibly issues with cross-loadings. Next confirmatory factor analysis was used on the second sample to verify the goodness of fit for the model. Finally, nomological validity was confirmed. Findings – First, this article develops and refines measures of empathy, moral obligation, self......Purpose – This paper aims to develop and validate measures of four constructs that have often been identified as antecedents of social entrepreneurial behavior: empathy with marginalized people, a feeling of moral obligation to help these, a high level of self-efficacy concerning the ability...... to effect social change and perceived availability of social support. Nomological validity is demonstrated by showing that, as specified by Mair and Noboa (2006), empathy and moral obligation are positively Associated with perceived desirability and self-efficacy and social support with perceived...

Breast manifestations of systemic diseases

Directory of Open Access Journals (Sweden)

Dilaveri CA

2012-02-01

Full Text Available Christina A Dilaveri, Maire Brid Mac Bride, Nicole P Sandhu, Lonzetta Neal, Karthik Ghosh, Dietlind L Wahner-RoedlerDivision of General Internal Medicine, Mayo Clinic, Rochester, MN, USAAbstract: Although much emphasis has been placed on the primary presentations of breast cancer, little focus has been placed on how systemic illnesses may affect the breast. In this article, we discuss systemic illnesses that can manifest in the breast. We summarize the clinical features, imaging, histopathology, and treatment recommendations for endocrine, vascular, systemic inflammatory, infectious, and hematologic diseases, as well as for the extramammary malignancies that can present in the breast. Despite the rarity of these manifestations of systemic disease, knowledge of these conditions is critical to the appropriate evaluation and treatment of patients presenting with breast symptoms.Keywords: breast, endocrine, hematologic, infectious, vascular

Efficacy of Submucosal Sodium Tetradecyl Sulfate in the Soft Palate as a Treatment of the Mild Obstructive Sleep Apnea Syndrome: A Pilot Study

Directory of Open Access Journals (Sweden)

Alberto Labra

2012-01-01

Full Text Available Background. As described by Mair et al. in 2001, snoreplasty, the application of sclerosant agents in the palate is a promising and cheap alternative to treat snoring. We decided to try this kind of therapy for the management of mild sleep apnea. Study Design. Experimental, longitudinal, prospective, nonrandomized, self-controlled pilot study. Methods. 11 patients were included, all of them with a polysomnographic study showing an Apnea-Hypopnea Index (AHI from 5 to 20, and with a Müller maneuver showing only retropalatal collapse. Results. We found significant decrease in the number of apneas hypopneas and oxygen desaturation as well as in the snoring index (<0.05, although no differences were found in the number of arousals. Conclusion. Sclerosant agents might become a relevant part in the treatment of sleep apnea, in very well-selected patients.

Surface proton transport of fully protonated poly(aspartic acid) thin films on quartz substrates

Science.gov (United States)

Nagao, Yuki; Kubo, Takahiro

2014-12-01

Thin film structure and the proton transport property of fully protonated poly(aspartic acid) (P-Asp100) have been investigated. An earlier study assessed partially protonated poly(aspartic acid), highly oriented thin film structure and enhancement of the internal proton transport. In this study of P-Asp100, IR p-polarized multiple-angle incidence resolution (P-MAIR) spectra were measured to investigate the thin film structure. The obtained thin films, with thicknesses of 120-670 nm, had no oriented structure. Relative humidity dependence of the resistance, proton conductivity, and normalized resistance were examined to ascertain the proton transport property of P-Asp100 thin films. The obtained data showed that the proton transport of P-Asp100 thin films might occur on the surface, not inside of the thin film. This phenomenon might be related with the proton transport of the biological system.

Strive toward data harmony of multi sensor aerosol data - Tribute to Dr. Gregory Leptoukh

Science.gov (United States)

Wei, J. C.; Lynnes, C.; Kempler, S. J.; Shen, S.

2012-12-01

The Goddard Earth Sciences Data and Information Services Center (GES DISC) has been involved with aerosol data synergy activities and projects over recent years, led by Dr. Gregory Leptoukh. His particular interests centered on issues related to comparison and harmonization of several aspects of aerosol data, such as data quality, bias adjustment, and data provenance. A thorough understanding of these issues is needed to guide multi-sensor data usage and avoid apples-to-oranges inter-comparison and data fusion. In this talk, I will highlight these activities/projects. These would include the tools developed, but also the projects that address specific user needs and innovative services, such as GIOVANNI-MAPSS, AeroStat, NEESPI, MAIRS, ATDD, MDSA, LTA-SWDB, etc. I will also discuss preliminary results from new projects and future goals that build on the ground breaking work, left by Dr. Leptoukh.

Krooniliste reumatoloogiliste haigete sotsiaalne toimetulek / Virve-Ines Laidmäe, Maire-Liis Hääl

Index Scriptorium Estoniae

Laidmäe, Virve-Ines, 1941-

2007-01-01

Krooniliste reumatoloogiliste haigete terviseseisundist, ravi kättesaadavusest ning toimetulekust haiguse ja igapäevaeluga. Uurimuse aluseks on rahvastikuküsitluse "Eesti 2003" ja küsitluse "Kroonilised reumatoloogilised haiged 2006" materjalid

Suicide Risk Associated with Experience of Violence and Impulsivity in Alcohol Dependent Patients.

Science.gov (United States)

Khemiri, Lotfi; Jokinen, Jussi; Runeson, Bo; Jayaram-Lindström, Nitya

2016-01-19

Alcohol dependence (AD) and aggression-impulsivity are both associated with increased suicide risk. There is a need to evaluate clinical tools in order to improve suicide risk assessment of AD patients. The present study consisted of 95 individuals with a diagnosis of AD, consecutively admitted for addiction treatment, compared with 95 healthy controls. Suicidal risk was assessed together with exposure of violence and impulsivity. AD patients reported significantly higher rates of exposure to violence in childhood, as measured by the Karolinska Interpersonal Violence Scale (KIVS), compared to HC. Within the AD group, individuals with history of suicidal ideation and suicidal behavior reported higher levels of violence experience compared to AD individuals without such history. AD patients with previous suicidal ideation scored higher on self-reported impulsivity as assessed by the Barratt Impulsivity Scale (BIS). Our main finding was that experience of trauma and expression of violent behavior, coupled with increased impulsivity are associated with an elevated suicide risk in AD patients. Future longitudinal studies assessing these traits are needed to evaluate their potential role in identifying AD patients at risk of future suicide.

Short outlines of books by Estonian authors / Brita Melts, Rutt Hinrikus, Maire Iro and Maret Vaher

Index Scriptorium Estoniae

2013-01-01

Arvustus: Pärtna, Maarja. Läved ja tüved. Tallinn : Eesti Keele Sihtasutus, 2013 ; Sauter, Peeter. Ära jäta mind rahule. Tallinn : P. Sauter, 2012 ; Viiding, Elo. Teised. Tallinn : Tuum, 2012 ; Mathura. Kumalasepäev. Lelle : Allikaäärne, 2012 ; Kadastik, Mart. Kevad saabub sügisel. Tallinn : Varrak, 2013 ; Mutt, Mihkel. Kooparahvas läheb ajalukku. Tallinn : Fabian, 2012 ; Hargla, Indrek. Apteeker Melchior ja Pirita kägistaja. Tallinn : Varrak, 2013 ; Raud, Rein. Rekonstruktsioon. Tallinn : Mustvalge Kirjastus, 2012 ; Toona, Elin. Into exile : a life story of war and peace. Woodsville (N.H.) : Lakeshore Press, 2013 ; Berg, Maimu. Moemaja. Tartu : Petrone Print, 2012 ; Kareva, Doris, Rooste, Jürgen. Elutants. Tallinn : Verb, 2013 ; Ehin, Kristiina. Paleontoloogi päevaraamat. Tartu : Petrone Print, 2013 ; Maria Lee. Stereomeetria. Tallinn : Verb, 2012

CineClub

CERN Multimedia

CineClub

2014-01-01

  On the occasion of CERN’s 60th anniversary the CERN CinéClub will be showing films from all CERN member states   Thursday 8 May 2014 at 20:00 CERN Council Chamber Tabu   Directed by Miguel Gomes (Portugal, 2012) 118 minutes      Directed by Jérome le Maire (Belgium, 2006) 87 minutes   TABU is a diptych starting off in present day Lisbon with Pilar, a woman concerned about her neighbour Aurora’s eccentricities.  Pilar meets Gian Luca, a man from Aurora’s past.  He starts his story and the film jumps back in time to colonial Africa, where he and Aurora had a passionate love affair. The second part is made of a quasi-silent film, with no dialogue, just music and voice-over. With a soundtrack that ranges from Lisztian piano music to cover versions of Phil Spector, TABU is just a delight.  Not to mention the sad and melancholy crocodile.. Original version P...

Modelling of IPO Underpricing in Bangladesh

Directory of Open Access Journals (Sweden)

Faysal Ahmad Khan

2017-07-01

Full Text Available This study shows the degree of underpricing in initial public offering in Bangladesh and the relationship of underpricing with some company specific and issue specific variables. To measure the degree of underpricing both initial return (IR and market adjusted initial returns (MAIR have been used. The study reveals 284% average initial return and 266% average market adjusted return for the first listing day of the IPOs for the period 2007 to 2016. Regression analysis is used to find the relationship between various predictor variables and underpricing. The regression analysis depicts that issue price, oversubscription, market return and size of the firm have significant effect on initial return. Similarly, market adjusted initial return is also influenced by issue price, oversubscription and size of the firm have significant effect over. The study found that issue size, age of the firm, floating percentage of share has very little relationship with underpricing in Bangladesh.

Política e Espetáculo: O Papel do Rádio nas Eleições de Uberlândia em 1958

Directory of Open Access Journals (Sweden)

Regma Maria dos Santos

2005-01-01

Full Text Available On prétend, dans ce text, construire quelques réflexions sur les relations entre les apparats techniques de la modernité, en special la radio, e la formation de personages politiques, comme le candidat à Maire, à la ville de Uberlândia, em 1958, Geraldo Ladeira. Interesse à nous comprendre le discours de ce candidat concilie par la radio et la pratique politique par lui implémentées dans son gouvernement. / Pretendemos, neste texto, construir algumas reflexões sobre a relação entre os aparatos técnicos da modernidade, em especial o rádio, e a formação de personagens políticos, como o candidato a prefeito, na cidade de Uberlândia, em 1958, Geraldo Ladeira. Interessa-nos compreender o discurso desse candidato, mediado pelo rádio e pela prática política por ele implementada em seu governo.

Cinnamic acid amides from Tribulus terrestris displaying uncompetitive α-glucosidase inhibition.

Science.gov (United States)

Song, Yeong Hun; Kim, Dae Wook; Curtis-Long, Marcus J; Park, Chanin; Son, Minky; Kim, Jeong Yoon; Yuk, Heung Joo; Lee, Keun Woo; Park, Ki Hun

2016-05-23

The α-glucosidase inhibitory potential of Tribulus terrestris extracts has been reported but as yet the active ingredients are unknown. This study attempted to isolate the responsible metabolites and elucidate their inhibition mechanism of α-glucosidase. By fractionating T. terristris extracts, three cinnamic acid amide derivatives (1-3) were ascertained to be active components against α-glucosidase. The lead structure, N-trans-coumaroyltyramine 1, showed significant inhibition of α-glucosidase (IC50 = 0.42 μM). Moreover, all active compounds displayed uncompetitive inhibition mechanisms that have rarely been reported for α-glucosidase inhibitors. This kinetic behavior was fully demonstrated by showing a decrease of both Km and Vmax, and Kik/Kiv ratio ranging between 1.029 and 1.053. We progressed to study how chemical modifications to the lead structure 1 may impact inhibition. An α, β-unsaturation carbonyl group and hydroxyl group in A-ring of cinnamic acid amide emerged to be critical functionalities for α-glucosidase inhibition. The molecular modeling study revealed that the inhibitory activities are tightly related to π-π interaction as well as hydrogen bond interaction between enzyme and inhibitors. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

An Admiralty for Asia: Isaac le Maire and conflicting conceptions about the corporate governance of the VOC

NARCIS (Netherlands)

O. Gelderblom (Oscar); A. de Jong (Abe); J. Jonker (Joost)

2010-01-01

textabstractThe Dutch East India Company or VOC in 1602 showed many characteristics of modern corporations, including limited liability, freely transferable shares, and well-defined managerial functions. However, we challenge the notion of the VOC as the precursor of modern corporations to argue

A robust method to screen detergents for membrane protein stabilization, revisited.

Science.gov (United States)

Champeil, Philippe; Orlowski, Stéphane; Babin, Simon; Lund, Sten; le Maire, Marc; Møller, Jesper; Lenoir, Guillaume; Montigny, Cédric

2016-10-15

This report is a follow up of our previous paper (Lund, Orlowski, de Foresta, Champeil, le Maire and Møller (1989), J Biol Chem 264:4907-4915) showing that solubilization in detergent of a membrane protein may interfere with its long-term stability, and proposing a protocol to reveal the kinetics of such irreversible inactivation. We here clarify the fact that when various detergents are tested for their effects, special attention has of course to be paid to their critical micelle concentration. We also investigate the effects of a few more detergents, some of which have been recently advertised in the literature, and emphasize the role of lipids together with detergents. Among these detergents, lauryl maltose neopentyl glycol (LMNG) exerts a remarkable ability, even higher than that of β-dodecylmaltoside (DDM), to protect our test enzyme, the paradigmatic P-type ATPase SERCA1a from sarcoplasmic reticulum. Performing such experiments for one's favourite protein probably remains useful in pre-screening assays testing various detergents. Copyright © 2016 Elsevier Inc. All rights reserved.

OUTREACH

CERN Multimedia

D. Barney

The CMS public web site is taking shape, with priority being given to a user-friendly interface to multimedia (photos, movies, podcasts). We expect that this part of the web-site will be fully operational by the end of the year. As we all know, 2008 will be a very special year for LHC and CMS. Not only will everything start to be commissioned, but underground visits to CMS and the other LHC installations will cease. Reflecting this, the CERN DG has decided to hold an "Open Weekend" in early April 2008, to give visitors a final opportunity to go underground. Saturday 5th April will be reserved for people who work at CERN and their families. Sunday 6th will be for the public, with priority being given to local residents. Preparations are already underway at Point 5 to cope with the thousands of visitors expected on those days, including a recent meeting with the Maire of Cessy. In addition to point 5, there will also be CMS visit sites at Meyrin building 40, CMS analysis centre, crystal la...

Antiviral activity of some Tunisian medicinal plants against Herpes simplex virus type 1.

Science.gov (United States)

Sassi, A Ben; Harzallah-Skhiri, F; Bourgougnon, N; Aouni, M

2008-01-10

Fifteen species of Tunisian traditional medicinal plants, belonging to 10 families, were selected for this study. They were Inula viscosa (L.) Ait and Reichardia tingitana (L.) Roth ssp. discolor (Pom.) Batt. (Asteraceae), Mesembryanthemum cristallinum L. and M. nodiflorum L. (Aizoaceae), Arthrocnemum indicum (Willd.) Moq., Atriplex inflata Muell., A. parvifolia Lowe var. ifiniensis (Caball) Maire, and Salicornia fruticosa L. (Chenopodiaceae), Cistus monspeliensis L. (Cistaceae), Juniperus phoenicea L. (Cupressaceae), Erica multiflora L. (Ericaceae), Frankenia pulverulenta L. (Frankeniaceae), Hypericum crispum L. (Hypericaceae), Plantago coronopus L. ssp. eu-coronopus Pilger var. vulgaris G.G. (Plantaginaceae) and Zygophyllum album L. (Zygophyllaceae). Fifty extracts prepared from those plants were screened in order to assay their antiviral activity against Herpes simplex virus type 1 (HSV-1), using neutral red incorporation. Extracts from eight plants among these 15 showed some degree of antiviral activity, while the methanolic extract of E. multiflora was highly active with EC(50) of 132.6 microg mL(-1). These results corroborate that medicinal plants from Tunisia can be a rich source of potential antiviral compounds.

Writing from the Margins of Myself

Directory of Open Access Journals (Sweden)

Luci Gorell Barnes

2014-02-01

Full Text Available In my doctoral studies at the University of Bristol, I took part in an experimental process of free writing, and my paper begins with the short story that emerged from this. During the taught unit we discussed ethical dilemmas that might arise from writing as inquiry, and in the commentary that follows my story, I reflect on how this practice requires an awareness of care for self and others. I describe my process, and discuss how it allowed me to transcend my dominant voice and restructure some of my ideas about what I study. I propose that by writing fiction I was able to consider complex issues in a way that opened up multiple meanings for me, and offered different views into social experience. I was guided by my practice as a visual artist and inspired by the writings of Ursula Le Guin (2004, Miller Mair (1989, and Ronald Pelias (2004, who encouraged me to listen in an empathic way, and write from the heart.

Essential oils of Pinus nigra J.F. Arnold subsp. laricio Maire: Chemical composition and study of their herbicidal potential

Directory of Open Access Journals (Sweden)

Ismail Amri

2017-05-01

Full Text Available The chemical composition of essential oils isolated by hydrodistillation from the needles of Tunisian Pinus nigra L. subsp. laricio was analyzed by GC and GC/MS. 27 compounds were identified, representing 97.9% of total oil, which was found to be rich in oxygenated diterpenes (38.5% particularly manool oxide (38% and sesquiterpene hydrocarbons (41.4% that included germacrene D (16.7%, δ-cadinene (9% and (E-caryophyllene (8.9%. Results of the herbicidal effects of the oil when tested on Phalaris canariensis L., Trifolium campestre Schreb. and Sinapis arvensis L., indicated that the oil completely inhibited germination and seedling growth at a high concentration (5 μL/mL−1, while at low doses the oil acted by decreasing germination and partially inhibiting seedling growth of all tested weeds.

Essential oils of Pinus nigra J.F. Arnold subsp. laricio Maire: Chemical composition and study of their herbicidal potential

OpenAIRE

Ismail Amri; Mohsen Hanana; Bassem Jamoussi; Lamia Hamrouni

2017-01-01

The chemical composition of essential oils isolated by hydrodistillation from the needles of Tunisian Pinus nigra L. subsp. laricio was analyzed by GC and GC/MS. 27 compounds were identified, representing 97.9% of total oil, which was found to be rich in oxygenated diterpenes (38.5%) particularly manool oxide (38%) and sesquiterpene hydrocarbons (41.4%) that included germacrene D (16.7%), δ-cadinene (9%) and (E)-caryophyllene (8.9%). Results of the herbicidal effects of the oil when tested on...

De Novo Biosynthesis of Glutarate via α-Keto Acid Carbon Chain Extension and Decarboxylation Pathway in Escherichia coli.

Science.gov (United States)

Wang, Jian; Wu, Yifei; Sun, Xinxiao; Yuan, Qipeng; Yan, Yajun

2017-10-20

Microbial based bioplastics are promising alternatives to petroleum based synthetic plastics due to their renewability and economic feasibility. Glutarate is one of the most potential building blocks for bioplastics. The recent biosynthetic routes for glutarate were mostly based on the l-lysine degradation pathway from Pseudomonas putida that required lysine either by feeding or lysine overproduction via genetic manipulations. Herein, we established a novel glutarate biosynthetic pathway by incorporation of a "+1" carbon chain extension pathway from α-ketoglutarate (α-KG) in combination with α-keto acid decarboxylation pathway in Escherichia coli. Introduction of homocitrate synthase (HCS), homoaconitase (HA) and homoisocitrate dehydrogenase (HICDH) from Saccharomyces cerevisiae into E. coli enabled "+1" carbon extension from α-KG to α-ketoadipate (α-KA), which was subsequently converted into glutarate by a promiscuous α-keto acid decarboxylase (KivD) and a succinate semialdehyde dehydrogenase (GabD). The recombinant E. coli coexpressing all five genes produced 0.3 g/L glutarate from glucose. To further improve the titers, α-KG was rechanneled into carbon chain extension pathway via the clustered regularly interspersed palindromic repeats system mediated interference (CRISPRi) of essential genes sucA and sucB in tricarboxylic acid (TCA) cycle. The final strain could produce 0.42 g/L glutarate, which was increased by 40% compared with the parental strain.

The 16th Werner Brandt Workshop on charged particle penetration phenomena

International Nuclear Information System (INIS)

1996-05-01

This report contains viewgraphs on the following topics: impact parameter dependence of charge transfer and energy loss; nonlinear dynamical response of the electron gas: comparison of some simple theories; stopping of ultrarelativistic ions in solids (33.2-TeV 108 Pb); collective excitation in reduced dimensionality; collective states in atoms and cluster; plasmon coupling with external probes; atomic collisions with antiprotons; layer-number scaling in ultra-thin film stopping and energetics; atom-surface scattering under classical conditions; nonlinear effect of sweeping-out electrons in stopping power and electron emission in cluster impacts; electron emission from fast grazing collisions of ions with silicon surfaces; electron emission from ultra-thin carbon foils by kiV ions; Auger rates for highly charged ions in metals; Auger and plasmon assisted neutralization at surfaces; low energy ( + and F - ions transmission through condensed layers of water: enhancement and attenuation processes; charge transfer for H interacting with Al: atomic levels and linewidths; scattered projectile angular and charge state distributions for grazing collisions of multicharged ions with metal and insulator single crystal targets; the prolate hyperboloidat model in scanning probe microscopy; scanning probe microscopy of large biomolecules; microcantilever sensors; solution of the Fokker-Planck equation for electron transport using analytic spatial moments; and effective charge parametrization for z = 3-17 projectiles in composite targets

Surface proton transport of fully protonated poly(aspartic acid) thin films on quartz substrates

Energy Technology Data Exchange (ETDEWEB)

Nagao, Yuki, E-mail: ynagao@jaist.ac.jp; Kubo, Takahiro

2014-12-30

Graphical abstract: - Highlights: • Proton transport of fully protonated poly(aspartic acid) thin film was investigated. • The thin film structure differed greatly from the partially protonated one. • Proton transport occurs on the surface, not inside of the thin film. • This result contributes to biological transport systems such as bacteriorhodopsin. - Abstract: Thin film structure and the proton transport property of fully protonated poly(aspartic acid) (P-Asp100) have been investigated. An earlier study assessed partially protonated poly(aspartic acid), highly oriented thin film structure and enhancement of the internal proton transport. In this study of P-Asp100, IR p-polarized multiple-angle incidence resolution (P-MAIR) spectra were measured to investigate the thin film structure. The obtained thin films, with thicknesses of 120–670 nm, had no oriented structure. Relative humidity dependence of the resistance, proton conductivity, and normalized resistance were examined to ascertain the proton transport property of P-Asp100 thin films. The obtained data showed that the proton transport of P-Asp100 thin films might occur on the surface, not inside of the thin film. This phenomenon might be related with the proton transport of the biological system.

In memoriam 2003

Index Scriptorium Estoniae

2004-01-01

Maailmas: Lynn Chadwick (24. XI 1914-25. IV), Eila Hiltunen (22. XI 1922-10. X), Leni Riefenstahl (22. VIII 1902-8. IX); Eesti: Paul Allik (23. XII 1946-14. XII), Tiiu Aru (14. X 1938-4. XII), Olga Bruns (19. III 1929-21. XII), Paula Delacherie-Ilves (7. IV 1903-2. IX), Tamara Ditman (9. VIII 1945-4. VIII), Ole Ehelaid (1. V 1913-2. IX), Mart-Ivo Eller (24. VII 1936-18. XI), Ene Falkenberg (2. XI 1914-10. III), Valve Janov (31. I 1921-18. IX), Aino Järvesoo (23. IX 1910-2. II), Lea Jürisson (31. X 1927-30. VIII), Ella Külv (1. XI 1921-31. VII), Tõnis Liik (1. XI 1923-25. I), Ella Loodma (27. II 1926-9. VI), Külli Muna (17. I 1960-8. I), Maire Männik (1. IV 1922-5. IX), Aleksei Paivel (30. III 1929-15. IX), Aino Põldra (1. VIII 1923-5. III), Made Põlluaas (13. VI 1929-15. X), Aleksander Suuman (25. IV 1927-19. VI), Walter Zapp (4. IX 1905-17. VII), Andres Tambek (7. VII 1952-12. V), Isi Trapido (27. IX 1921-28. XI), Ants Erik Vomm (4. VI 1931-11. VIII)

Surface proton transport of fully protonated poly(aspartic acid) thin films on quartz substrates

International Nuclear Information System (INIS)

Nagao, Yuki; Kubo, Takahiro

2014-01-01

Graphical abstract: - Highlights: • Proton transport of fully protonated poly(aspartic acid) thin film was investigated. • The thin film structure differed greatly from the partially protonated one. • Proton transport occurs on the surface, not inside of the thin film. • This result contributes to biological transport systems such as bacteriorhodopsin. - Abstract: Thin film structure and the proton transport property of fully protonated poly(aspartic acid) (P-Asp100) have been investigated. An earlier study assessed partially protonated poly(aspartic acid), highly oriented thin film structure and enhancement of the internal proton transport. In this study of P-Asp100, IR p-polarized multiple-angle incidence resolution (P-MAIR) spectra were measured to investigate the thin film structure. The obtained thin films, with thicknesses of 120–670 nm, had no oriented structure. Relative humidity dependence of the resistance, proton conductivity, and normalized resistance were examined to ascertain the proton transport property of P-Asp100 thin films. The obtained data showed that the proton transport of P-Asp100 thin films might occur on the surface, not inside of the thin film. This phenomenon might be related with the proton transport of the biological system

Les maires confrontés à l'apprentissage de l'intercommunalité : l'exemple de l'agglomération toulousaine

OpenAIRE

Loubet , Lilian

2011-01-01

The development of the inter-municipal cooperation gives rise to some major territorial and governmental reorganization. The elected in charge are then confronted to the complex exercise of the inter-municipal cooperation and the definition of a territorial project. It will be a question of studying the inter-municipal cooperation towards the technical, political and territorial apprenticeships operated by the mayors. That is illustrated by the study of the Toulouse city région, which is spli...

Family history of suicide and exposure to interpersonal violence in childhood predict suicide in male suicide attempters.

Science.gov (United States)

Rajalin, Mia; Hirvikoski, Tatja; Jokinen, Jussi

2013-05-15

Family studies, including twin and adoption designs, have shown familial transmission of suicidal behaviors. Early environmental risk factors have an important role in the etiology of suicidal behavior. The aim of the present study was to assess the impact of family history of suicide and childhood trauma on suicide risk and on severity of suicide attempt in suicide attempters. A total of 181 suicide attempters were included. Family history of suicide was assessed with the Karolinska Suicide History Interview or through patient records. Childhood trauma was assessed with the Karolinska Interpersonal Violence Scale (KIVS) measuring exposure to violence and expressed violent behavior in childhood (between 6 and 14 years of age) and during adult life (15 years or older). Suicide intent was measured with the Freeman scale. Male suicide attempters with a positive family history of suicide made more serious and well planned suicide attempts and had a significantly higher suicide risk. In logistic regression, family history of suicide and exposure to interpersonal violence as a child were independent predictors of suicide in male suicide attempters. The information about family history of suicide and exposure to interpersonal violence as a child derives from the patients only. In the first part of the inclusion period the information was collected from patient records. The results of this study imply that suicides among those at biological risk might be prevented with the early recognition of environmental risks. Copyright © 2012 Elsevier B.V. All rights reserved.

Not only size matters: achene morphology affects time of seedling emergence in three heterocarpic species of Anacyclus (Anthemideae, Asteraceae

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Torices, Rubén

2013-06-01

Full Text Available The production of two or more distinct fruit types by an individual, i.e. heterocarpy, is considered as a mixed dispersal strategy in which a proportion of the offspring is able to colonize new sites, whilst others remain near the maternal location. Here, we aimed to explore the effects of achene morphology (winged vs. unwinged achenes and achene size –measured here as achene mass– on post-dispersal life-history traits (probability and time of seedling emergence in three heterocarpic Anacyclus species (Anthemideae, Asteraceae. Morphology, size and germination performance were studied in achenes from six populations of Anacyclus clavatus (Desf. Pers., A. homogamos (Maire Humphries, and A. valentinus L. Our results show that achene morphology and size were related to their position within the capitulum, such that outer, winged achenes were significantly heavier than the inner, unwinged ones. Additionally, winged achenes germinated faster than unwinged ones. This pattern may be related to the sequential achene time of release displayed by these species. Finally, our findings cast doubt on the role of wings as structures that favor dispersal by wind in these three species of Anacyclus.La producción de dos o más tipos de frutos diferentes por un mismo individuo, i.e. heterocarpia, es considerada como una estrategia mixta de dispersión en la que una parte de la descendencia es capaz de colonizar nuevos sitios, mientras que la otra permanece cerca de la planta madre. En este trabajo, nuestro objetivo fue explorar los efectos de la morfología del aquenio (aquenios alados vs. no alados y de su tamaño –medido aquí como masa del aquenio– en la etapa del ciclo de vida siguiente a la dispersión (probabilidad de germinación y tiempo de emergencia de las plántulas de tres especies heterocárpicas del género Anacyclus (Anthemideae, Asteraceae. Se estudió la morfología, el tamaño y la germinación en aquenios de seis poblaciones de Anacyclus

Paradoxical sleep deprivation changes testicular malondialdehyde and caspase-3 expression in male rats

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Fitranto Arjadi

2015-08-01

Full Text Available BACKGROUND Sleep deprivation is a significant problem among adult men and is considered as a risk factor for several diseases. Paradoxical sleep deprivation (PSD induces Leydig cell apoptosis through elevation of corticosterone, with testicular malondialdehyde (MDA and Leydig cell caspase-3 expression as parameters. The aim of this study was to observe testicular MDA level and caspase-3 expression treated with paradoxical sleep deprivation (PSD, immobilization, and footshock stress and to determine the stress model with a significant effect in white male rats (Rattus norvegicus . METHODS This experimental randomized study of posttest only with control group design was conducted on 24 white male Wistar strain rats, randomly allocated into four treatment groups, i.e. control (K1 without any stress treatment, PSD (KII, immobilization (KIII, and footshock stress (KIV. Treatments were given for 25 days to produce chronic stress. Testicular MDA concentration was examined by the ELISA method while caspase-3 was examined by the TUNEL method. RESULTS Mean testicular MDA concentration with one-way ANOVA test showed differences in means between the groups (p=0.000 and post hoc Tukey-HSD test showed significant results between PSD stress group versus control, immobilization and footshock stress groups. One-way ANOVA test showed a significant difference in caspase-3 expression in at least two treatment groups (p=0.008 and post-hoc Tuckey-LSD test showed significant differences between controls and all stress groups. CONCLUSION Sleep deprivation is a type of stress inducing changes in testicular MDA concentration and caspase-3 expression in male rat testes.

Comparison between Fenugreek and Lovastatin in restoration of endothelial function in an experimental old rat model

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"Pipelzadeh MH

2003-06-01

Full Text Available The aim of this study was to compare the effectiveness of Fenugreek (Trigonella foenum-graecum with that of lovastatin in restoration of endothelia function in the aorta taken form aged N-Mair rats. For this purpose, 4 groups of old N-Mari rats were used (n=6, normal saline treated control group, lovastatin (10 mg/kg, orally and fengreek seed powder in normal saline suspension (100 or 500 mg/kg were administered orally daily for 8 weeks. The rate of relaxation of ephedrine- precontracted aorta to acetycholine, the lipid profiles, and histological examinations of the aorta were compared between these two groups and with a control non-treated normal saline treated group. The results showed that treatment with lovastatin and fenugreek produced significant reduction in IDL, VLDL triglyceride and total cholesterol, while HDL was increased as compared to control non-treated group. Lovastatin induced an increase in contraction/mg tissue weight. However, improvement in endothelial function was significantly increased in all treatment groups. The histological findings showed significant reduction in thickness and lipid deposits in the aorta in all treatment groups. The improvement in the epithelial function was correlated with LDL-cholesterol lowering and partly with the reduction in the thickness of the aortic intimal layer. This study demonstrated that fenugreek is as effective as lovastatin in reducing the features associated with atherosclerosis.

Midline thalamic reuniens lesions improve executive behaviors.

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Prasad, J A; Abela, A R; Chudasama, Y

2017-03-14

The role of the thalamus in complex cognitive behavior is a topic of increasing interest. Here we demonstrate that lesions of the nucleus reuniens (NRe), a midline thalamic nucleus interconnected with both hippocampal and prefrontal circuitry, lead to enhancement of executive behaviors typically associated with the prefrontal cortex. Rats were tested on four behavioral tasks: (1) the combined attention-memory (CAM) task, which simultaneously assessed attention to a visual target and memory for that target over a variable delay; (2) spatial memory using a radial arm maze, (3) discrimination and reversal learning using a touchscreen operant platform, and (4) decision-making with delayed outcomes. Following NRe lesions, the animals became more efficient in their performance, responding with shorter reaction times but also less impulsively than controls. This change, combined with a decrease in perseverative responses, led to focused attention in the CAM task and accelerated learning in the visual discrimination task. There were no observed changes in tasks involving either spatial memory or value-based decision making. These data complement ongoing efforts to understand the role of midline thalamic structures in human cognition, including the development of thalamic stimulation as a therapeutic strategy for acquired cognitive disabilities (Schiff, 2008; Mair et al., 2011), and point to the NRe as a potential target for clinical intervention. Published by Elsevier Ltd.

What Does It Mean to be Central? A Botanical Geography of Paris 1830-1848.

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Hoquet, Thierry

2016-02-01

This paper focuses on the geography of the botanical community in Paris, under the July Monarchy (1830-1848). At that time, the Muséum d'Histoire naturelle (MHN) was at its institutional acme and, under the impulse of François Guizot, its budget was increasing dramatically. However, closer attention to manuscript sources (correspondence, travel diaries) reveals that the botanists of the time favoured other private institutions, located both on the Right and Left Banks of the Seine. The MHN was prestigious for its collections and professors but it was relatively remote from the centre of Paris, and its plant samples were sometimes difficult to access. Several other first-class private herbaria granted liberal access to botanists: those of Jacques Gay, Phillip Barker Webb, and Benjamin Delessert. Thanks to their wealth, these plant amateurs had ownership of historical herbaria consisting of species types alongside rich botanical libraries. Botanists visiting Paris from foreign countries or other provinces of France also spent some time studying less general plant collections, like those of Count Jaubert, or specialized collections, like Montagne's or Léveillé's on cryptogams. Other botanists also enjoyed renown at the time, although they published little, if anything (like Maire). Living in crammed apartments, literally in the middle of their plant samples, these botanists were key nodes in botanical networks, although they had no relation with the prestigious MHN.

Mechanical properties of carving wax with various Ca-bentolite filter composition

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Widjijono Widjijono

2009-09-01

Full Text Available Background: The carving wax is used as a medium in dental anatomy study. This wax composes of many waxes and sometimes a filler is added. Carving wax is not sold in Indonesian market. Whereas the gradients of carving wax such as beeswax, paraffin and bentonite are abundant in Indonesia. Based on that fact, to make high quality and standard,the exact composition if this carving wax should be known. Purpose: The aim of this study was to investigate the effect of carving wax composition with Ca-bentonite filler on the melting point, hardness, and thermal expansion. Methods: Five carving wax compositions were made with paraffin, Ca-bentonite, carnauba wax, and beeswax in ratio (% weight: 50:20:25:5 (KI, 55:15:25:5 (KII, 60:10:25:5 (KIII, 65:5:25:5 (KIV, 70:0:25:5(KV. All components were melted, then poured into the melting point, hardness, and thermal expansion moulds (n = 5. Three carving wax properties were tested: melting point by melting point apparatus; hardness by penetrometer; thermal expansion by digital sliding caliper. The data were analyzed statistically using One-Way ANOVA and LSD0.05. Result: The Ca-bentonite addition influenced the melting point and thermal expansion of carving wax with significant differences between KI and other groups (p < 0.05. Ca-bentonite addition influenced the carving wax hardness and the mean differences among the groups were significant (p < 0.05. Conclusion: Ca-bentonite filler addition on the composition of carving wax influenced the physical and mechanical properties. The carving wax with high Ca-bentonite concentration had high melting point and hardness, but low thermal expansion.

A Higgs-bozon

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Dezso, Horvath

2017-01-01

A részecskefizika általánosan elfogadott és az elmúlt 40 év alatt sokszorosan igazolt elmélete, a standard modell valamennyi alkatrészét sikerült megfigyelni és tanulmányozni a Higgs-bozon kivételével. A CERN nagy hadronütköztetője (LHC), a világ legnagyobb részecskegyorsítója is elsősorban a Higgs-részecske kimutatására épült. 2012 közepére az LHC két óriási mérőberendezése, a sok ezer fizikus részvételével épült CMS és ATLAS megfigyelt egy - a Higgs-bozon elméletileg megjósolt tulajdonságaival rendelkező - új részecskét. A könyv áttekinti a standard modell elméletét és a Higgs-részecske feltételezett tulajdonságait, majd összefoglalja az LHC Higgs-keresési eredményeit és a hozzájuk vezető utat. Függelékben ismerteti a könyvben előforduló fizikusok életrajzát és bizonyos fizikai fogalmak részletesebb leírását. A 2013-as fizikai Nobel-díjat Peter Higgs és François Englert kapták megosztva a Higgs-mechanizmus és a Higgs-bozon elmé...

The correlation between Salter's criteria for avascular necrosis of the femoral head and Kalamchi's prognostic classification following the treatment of developmental dysplasia of the hip.

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Tsukagoshi, Y; Kamegaya, M; Kamada, H; Saisu, T; Morita, M; Kakizaki, J; Tomaru, Y; Yamazaki, M

2017-08-01

The aim of this study was to evaluate the correlation between Salter's criteria and Kalamchi's classification of avascular necrosis in patients treated for developmental dysphasia of the hip (DDH). The study involved a retrospective analysis of 123 patients (123 hips) with DDH treated by operative and non-operative reduction before the age of two years, with a minimum follow-up of ten years. Salter's criteria (S1 to S4) were determined from radiographs obtained at one to two years post-reduction, whilst the Kalamchi grade was determined from radiographs obtained at ten or more years of age. Early post-reduction radiographs were also used to evaluate the centre-head distance discrepancy (CHDD) and the occurrence of a dome-shaped deformity of the proximal femoral metaphysis (D-shaped metaphysis). The prognosis was described as good (Kalamchi grade K0 or KI), fair (Kalamchi grade KII) or poor (Kalamchi grade KIII or KIV) for analysis and correlation with the early Salter criteria, CHDD and D-shaped metaphysis. S1 and S2 criteria were predictive of a poor prognosis. The outcome following S3, S4 and S3 + S4 varied; 18 (40%) had a good prognosis, 17 (38%) a fair prognosis and ten (22%) a poor prognosis. A CHDD ≥ 10% and a D-shaped metaphysis were also predictive of a poor prognosis. The Salter criteria were predictive of the Kalamchi grade of avascular necrosis in patients with DDH aged ten or more years after reduction of the hip. Cite this article: Bone Joint J 2017;99-B:1115-20. ©2017 The British Editorial Society of Bone & Joint Surgery.

Absence of an association of human polyomavirus and papillomavirus infection with lung cancer in China: a nested case–control study

International Nuclear Information System (INIS)

Colombara, Danny V.; Manhart, Lisa E.; Carter, Joseph J.; Hawes, Stephen E.; Weiss, Noel S.; Hughes, James P.; Qiao, You-Lin; Taylor, Philip R.; Smith, Jennifer S.; Galloway, Denise A.

2016-01-01

Studies of human polyomavirus (HPyV) infection and lung cancer are limited and those regarding the association of human papillomavirus (HPV) infection and lung cancer have produced inconsistent results. We conducted a nested case–control study to assess the association between incident lung cancer of various histologies and evidence of prior infection with HPyVs and HPVs. We selected serum from 183 cases and 217 frequency matched controls from the Yunnan Tin Miner’s Cohort study, which was designed to identify biomarkers for early detection of lung cancer. Using multiplex liquid bead microarray (LBMA) antibody assays, we tested for antibodies to the VP1 structural protein and small T antigen (ST-Ag) of Merkel cell, KI, and WU HPyVs. We also tested for antibodies against HPV L1 structural proteins (high-risk types 16, 18, 31, 33, 52, and 58 and low-risk types 6 and 11) and E6 and E7 oncoproteins (high risk types 16 and 18). Measures of antibody reactivity were log transformed and analyzed using logistic regression. We found no association between KIV, WUV, and MCV antibody levels and incident lung cancer (P-corrected for multiple comparisons >0.10 for all trend tests). We also found no association with HPV-16, 18, 31, 33, 52, and 58 seropositivity (P-corrected for multiple comparisons >0.05 for all). Future studies of infectious etiologies of lung cancer should look beyond HPyVs and HPVs as candidate infectious agents. The online version of this article (doi:10.1186/s12885-016-2381-3) contains supplementary material, which is available to authorized users

NASA Land Cover and Land Use Change (LCLUC): an interdisciplinary research program.

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Justice, Chris; Gutman, Garik; Vadrevu, Krishna Prasad

2015-01-15

Understanding Land Cover/Land Use Change (LCLUC) in diverse regions of the world and at varied spatial scales is one of the important challenges in global change research. In this article, we provide a brief overview of the NASA LCLUC program, its focus areas, and the importance of satellite remote sensing observations in LCLUC research including future directions. The LCLUC Program was designed to be a cross-cutting theme within NASA's Earth Science program. The program aims to develop and use remote sensing technologies to improve understanding of human interactions with the environment. Since 1997, the NASA LCLUC program has supported nearly 280 research projects on diverse topics such as forest loss and carbon, urban expansion, land abandonment, wetland loss, agricultural land use change and land use change in mountain systems. The NASA LCLUC program emphasizes studies where land-use changes are rapid or where there are significant regional or global LCLUC implications. Over a period of years, the LCLUC program has contributed to large regional science programs such as Land Biosphere-Atmosphere (LBA), the Northern Eurasia Earth Science Partnership Initiative (NEESPI), and the Monsoon Area Integrated Regional Study (MAIRS). The primary emphasis of the program will remain on using remote sensing datasets for LCLUC research. The program will continue to emphasize integration of physical and social sciences to address regional to global scale issues of LCLUC for the benefit of society. Copyright © 2014. Published by Elsevier Ltd.

Assessment of urban heat Island for Craiova from satellite-based LST

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Udristioiu, Mihaela Tinca; Velea, Liliana; Bojariu, Roxana; Sararu, Silviu Constantin

2017-12-01

The urban heat island is defined as an excess of heating in urban areas compared with surrounding rural zones which is illustrated by higher surface and air temperatures in the inner part of the cities. The aim of this study is to identify the UHI effect for Craiova - the largest city in the South-Western part of Romania - and to assess its intensity during summer. To this end, MODIS Land surface temperature (LST) for day and night for summer months (June, July, August), in the interval 2002-2017, as well as yearly Land Cover Type (LCT) data also from MODIS were employed. Furthermore, measurements of air and soil temperature from meteorological station Craiova, available from the National Meteorological Administration database, were used to investigate their relation with LST. The analysis shows that in the urban area of Craiova the long-term summer mean LST is about 4 °C (2 °C), higher than in the rural area during daytime (nighttime). During high temperatures episodes, the mean daytime LST reaches 45-47 °C in the city, while the difference from the rural surrounding area is of 2-3 °C. A high correlation (0.77-0.83) is found between LST and air temperature for all land-use types in the area considered. Both LST and 2m-air temperature time-series manifest an increasing linear tendency over the period considered, being more pronounced during the day.

Development of a 3D cell-centered Lagrangian scheme for the numerical modeling of the gas dynamics and hyper-elasticity systems

International Nuclear Information System (INIS)

Georges, Gabriel

2016-01-01

High Energy Density Physics (HEDP) flows are multi-material flows characterized by strong shock waves and large changes in the domain shape due to rare faction waves. Numerical schemes based on the Lagrangian formalism are good candidates to model this kind of flows since the computational grid follows the fluid motion. This provides accurate results around the shocks as well as a natural tracking of multi-material interfaces and free-surfaces. In particular, cell-centered Finite Volume Lagrangian schemes such as GLACE (Godunov-type Lagrangian scheme Conservative for total Energy) and EUCCLHYD (Explicit Unstructured Cell-Centered Lagrangian Hydrodynamics) provide good results on both the modeling of gas dynamics and elastic-plastic equations. The work produced during this PhD thesis is in continuity with the work of Maire and Nkonga [JCP, 2009] for the hydrodynamic part and the work of Kluth and Despres [JCP, 2010] for the hyper elasticity part. More precisely, the aim of this thesis is to develop robust and accurate methods for the 3D extension of the EUCCLHYD scheme with a second-order extension based on MUSCL (Monotonic Upstream-centered Scheme for Conservation Laws) and GRP (Generalized Riemann Problem) procedures. A particular care is taken on the preservation of symmetries and the monotonicity of the solutions. The scheme robustness and accuracy are assessed on numerous Lagrangian test cases for which the 3D extensions are very challenging. (author) [fr

Desenvolvimento de coleções: origem dos fundamentos contemporâneos

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Simone da Rocha Weitzel

Full Text Available O artigo apresenta o resultado de uma pesquisa cujo objetivo foi identificar as correspondências entre os fundamentos da área hoje denominada de desenvolvimento de coleções e aqueles estabelecidos no século XIX, a fim de reconstruir os principais conceitos, métodos e práticas da área. Propõe um estudo exploratório para viabilizar essa correspondência a partir de oito obras escolhidas de autores europeus do século XIX, a maioria bibliófilos reconhecidos, a saber: Peignot (1823, Namur (1834, Hesse (1841, Rouveyre (1878, Richard (1883, Gräsel (1893, Petzholdt (1894 e Maire (1896. Essas obras serão analisadas a partir de três categorias contemporâneas da área: desenvolvimento de coleções, seleção e aquisição, por meio do método de revisão de literatura. Conclui-se, por fim, que o fenômeno da explosão da informação afeta o processo de desenvolvimento de coleções como um todo desde o século XVIII. Os autores do século XIX selecionados para o estudo apresentaram várias soluções - as quais fortaleceram o que hoje é denominado de abordagem baseada no acesso à informação - para lidar com a complexidade gerada pelo fenômeno da explosão da informação.

Aqueous benzene-diols react with an organic triplet excited state and hydroxyl radical to form secondary organic aerosol.

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Smith, Jeremy D; Kinney, Haley; Anastasio, Cort

2015-04-21

Chemical processing in atmospheric aqueous phases, such as cloud and fog drops, can play a significant role in the production and evolution of secondary organic aerosol (SOA). In this work we examine aqueous SOA production via the oxidation of benzene-diols (dihydroxy-benzenes) by the triplet excited state of 3,4-dimethoxybenzaldehyde, (3)DMB*, and by hydroxyl radical, ˙OH. Reactions of the three benzene-diols (catechol (CAT), resorcinol (RES) and hydroquinone (HQ)) with (3)DMB* or ˙OH proceed rapidly, with rate constants near diffusion-controlled values. The two oxidants exhibit different behaviors with pH, with rate constants for (3)DMB* increasing as pH decreases from pH 5 to 2, while rate constants with ˙OH decrease in more acidic solutions. Mass yields of SOA were near 100% for all three benzene-diols with both oxidants. We also examined the reactivity of atmospherically relevant mixtures of phenols and benzene-diols in the presence of (3)DMB*. We find that the kinetics of phenol and benzene-diol loss, and the production of SOA mass, in mixtures are generally consistent with rate constants determined in experiments containing a single phenol or benzene-diol. Combining our aqueous kinetic and SOA mass yield data with previously published gas-phase data, we estimate a total SOA production rate from benzene-diol oxidation in a foggy area with significant wood combustion to be nearly 0.6 μg mair(-3) h(-1), with approximately half from the aqueous oxidation of resorcinol and hydroquinone, and half from the gas-phase oxidation of catechol.

Online Time Series Analysis of Land Products over Asia Monsoon Region via Giovanni

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Shen, Suhung; Leptoukh, Gregory G.; Gerasimov, Irina

2011-01-01

Time series analysis is critical to the study of land cover/land use changes and climate. Time series studies at local-to-regional scales require higher spatial resolution, such as 1km or less, data. MODIS land products of 250m to 1km resolution enable such studies. However, such MODIS land data files are distributed in 10ox10o tiles, due to large data volumes. Conducting a time series study requires downloading all tiles that include the study area for the time period of interest, and mosaicking the tiles spatially. This can be an extremely time-consuming process. In support of the Monsoon Asia Integrated Regional Study (MAIRS) program, NASA GES DISC (Goddard Earth Sciences Data and Information Services Center) has processed MODIS land products at 1 km resolution over the Asia monsoon region (0o-60oN, 60o-150oE) with a common data structure and format. The processed data have been integrated into the Giovanni system (Goddard Interactive Online Visualization ANd aNalysis Infrastructure) that enables users to explore, analyze, and download data over an area and time period of interest easily. Currently, the following regional MODIS land products are available in Giovanni: 8-day 1km land surface temperature and active fire, monthly 1km vegetation index, and yearly 0.05o, 500m land cover types. More data will be added in the near future. By combining atmospheric and oceanic data products in the Giovanni system, it is possible to do further analyses of environmental and climate changes associated with the land, ocean, and atmosphere. This presentation demonstrates exploring land products in the Giovanni system with sample case scenarios.

Impact of hypoglycemia on daily life of type 2 diabetes patients in Ukraine

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Mandrik O

2013-07-01

Full Text Available Olena Mandrik,1–3 Johan L Severens,1 Olena Doroshenko,4 Vladymir Pan'kiv,5 Nonna Kravchun,6 Maryna Vlasenko,7 Mykola Hulchiy,8 Maryna Baljuk,9 Yuliia Komisarenko,10 Eugene Martsynik,11 Liubov Sokolova,12 Olga Zalis'ka,2 Boris Mankovsky131Erasmus University Rotterdam, Rotterdam, the Netherlands; 2Danylo Halytsky Lviv National Medical University, Lviv, 3MSD Ukraine, 4Ukrainian Institute for Strategic Research, 5Ukrainian Scientific Centre of Endocrine Surgery, 6Institute of Problems of Endocrine Pathology na VY Danylevskogo, Ukrainian Academy of Medical Sciences, Kyiv, 7Vinnitsa National Medical University named after MI Pyrogov, Vinnytsia, 8Kyiv City Teaching Endocrinological Center, Kyiv, 9Danilevsky Institute of Endocrine Pathology Problems, Ukrainian Academy of Medical Sciences, Kharkov, 10OO Bogomolets National Medical University, Kyiv, 11Medical Academy of Dnepropetrovsk, Dnepropetrovsk, 12Institute of Endocrinology and Metabolism after V.P. Komissarenko, National Academy of Medical Sciences of Ukraine, Kyiv, 13PL Shupik National Medical Academy of Postgraduate Education, Kyiv, UkraineAbstract: This study evaluates the impact of hypoglycemia on the lives of Ukrainian patients with type 2 diabetes mellitus. The secondary objective was to explore patient–physician relationships and the attitudes of patients towards various informational resources on diabetes management. Three focus groups with 26 patients were conducted. Qualitative information was evaluated using content analysis. The results show that patients with type 2 diabetes mellitus in Ukraine are adapting to potential attacks of hypoglycemia; however, they still experience periodic manifestations of hypoglycemia that significantly affect their psychological well-being. This result is similar to observations made in other countries. Ukrainian patients >40 years old mainly receive information on disease management from endocrinologists, and rarely use internet resources on diabetes

Determination of branched chain amino acids, methionine, phenylalanine, tyrosine and alpha-keto acids in plasma and dried blood samples using HPLC with fluorescence detection.

Science.gov (United States)

Kand'ár, Roman; Záková, Pavla; Jirosová, Jana; Sladká, Michaela

2009-01-01

The determination of branched chain amino acids [BCAA; valine (Val), leucine (Leu), isoleucine (Ile)], alpha-keto acids derived from BCAA [BCKA; alpha-ketoisovaleric acid (KIV), alpha-ketoisocaproic acid (KIC), alpha-ketomethylvaleric acid (KMV)], methionine (Met), phenylalanine (Phe) and tyrosine (Tyr) is currently the most reliable approach for the diagnosis of maple syrup urine disease (MSUD), hypermethioninemia, phenylketonuria (PKU) and tyrosinemia. The aim of this study was to develop rapid and simple HPLC methods for measurement of BCAA, Met, Phe, Tyr and BCKA in plasma and dried blood samples. Samples of peripheral venous blood with EDTA as anticoagulant were obtained from a group of healthy blood donors (n=70, 35 females, 27-41 years of age and 35 males, 28-43 years of age). Blood-spot samples from a group of newborns (n=80, 40 girls and 40 boys 3-5 days of age) were collected onto #903 Specimen Collection Paper and allowed to dry for at least 24 h before analysis. Prior to separation, the amino acids (AA) were derivatized with o-phthaldialdehyde (OPA) and BCKA with o-phenylenediamine (OPD). Reverse phase column chromatography (LiChroCart 125-4 Purospher RP-18e, 5 microm) was used for separation and fluorescence detection used to monitoring of effluent. For AA analysis, 25 mmol/L sodium hydrogenphosphate-methanol (90:10, v/v), pH 6.5+/-0.1 was used as mobile phase A and 100% methanol was used as mobile phase B. Measurement of BCKA used a mixture of methanol and deionized water (55:45, v/v) as mobile phase A and mobile phase B consisted of 100% methanol. Analytical performance of these methods was satisfactory for the determination of all AA and BCKA. The intra-assay and inter-assay coefficients of variation were below 10% and recovery ranged from 90%-110%. We have developed simple, rapid and selective HPLC methods with fluorescence detection for the determination of BCAA, Met, Phe, Tyr and BCKA in plasma and dried blood samples.

Genetic variants in FBN-1 and risk for thoracic aortic aneurysm and dissection.

Science.gov (United States)

Iakoubova, Olga A; Tong, Carmen H; Rowland, Charles M; Luke, May M; Garcia, Veronica E; Catanese, Joseph J; Moomiaie, Remo M; Sotonyi, Peter; Ascady, Gyorgy; Nikas, Demitrios; Dedelias, Panagiotis; Tranquilli, Maryann; Elefteriades, John A

2014-01-01

A recent genome wide association study (GWAS) by LeMaire et al. found that two single nucleotide polymorphisms (SNPs), rs2118181 and rs10519177 in the FBN-1 gene (encoding Fibrillin-1), were associated with thoracic aortic dissection (TAD), non-dissecting thoracic aortic aneurysm (TAA), and thoracic aortic aneurysm or dissection (TAAD); the largest effect was observed for the association of rs2118181 with TAD. We investigated whether rs2118181 and rs10519177 were associated with TAD, TAA, and TAAD in the Yale study. The genotypes of rs2118181 and rs10519177 were determined for participants in the Yale study: 637 TAAD cases (140 TAD, 497 TAA) and 275 controls from the United States, Hungary, and Greece. The association of the genotypes with TAD, TAA and TAAD were assessed using logistic regression models adjusted for sex, age, study center and hypertension. In the Yale study, rs2118181 was associated with TAD: compared with non-carriers, carriers of the risk allele had an unadjusted odds ratio for TAD of 1.80 (95% CI 1.15-2.80) and they had odds ratio for TAD of 1.87 (95% CI 1.09-3.20) after adjusting for sex, age, study center and hypertension. We did not find significant differences in aortic size, a potential confounder for TAD, between rs2118181 risk variant carriers and non-carriers: mean aortic size was 5.56 (95% CI: 5.37-5.73) for risk variant carriers (CC+CT) and was 5.48 (95% CI: 5.36-5.61) for noncarriers (TT) (p = 0.56). rs2118181 was not associated with TAA or TAAD. rs10519177 was not associated with TAD, TAA, or TAAD in the Yale study. Thus, the Yale study provided further support for the association of the FBN-1 rs2118181SNP with TAD.

A shock tube study of C4–C6 straight chain alkenes + OH reactions

KAUST Repository

Khaled, Fathi

2016-06-28

Alkenes are known to be good octane boosters and they are major components of commercial fuels. Detailed theoretical calculations and direct kinetic measurements of elementary reactions of alkenes with combustion radicals are scarce for C4 alkenes and they are practically absent for C5 and larger alkenes. The overall rate coefficients for the reaction of OH radical with 1-butene (CH CHCH CH, k ), 1-pentene (CH CHCH CH-CH, k ), cis/trans 2-pentene (CH CHCHCH CH, k and k ), 1-hexene (CH CHCH CH CH CH, k ) and cis/trans 2-hexene (CH CHCHCH CH CH, k and k ) were measured behind reflected shock waves over the temperature range of 833-1377K and pressures near 1.5atm. The reaction progress was followed by measuring mole fraction of OH radicals near 306.7nm using UV laser absorption technique. It is found that the rate coefficients of OH+trans-2-alkenes are larger than those of OH+cis-2-alkenes, followed by OH+1-alkenes. The derived Arrhenius expressions for the overall rate coefficients (in cm.mol.s) are:. kI=(4.83±0.03)104.T2.72±0.01.exp(940.8±2.9cal/molRT)(946K-1256K) + kII=(5.66±0.54)10-1.T4.14±0.80.exp(4334±227cal/molRT)(875K-1379K) + kIII=(3.25±0.12)104.T2.76±0.5.exp(1962±83cal/molRT)(877K-1336K) + kIV=(3.42±0.09)104.T2.76±0.5.exp(1995±59cal/molRT)(833K-1265K) + kV=(7.65±0.58)10-4.T5±1.exp(5840±175cal/molRT)(836K-1387K) + kVI=(2.58±0.06)106.T2.17±0.37.exp(1461±55cal/molRT)(891K-1357K) + kVII=(3.08±0.05)106.T2.18±0.37.exp(1317±38cal/molRT)(881K-1377K) +

A shock tube study of C4–C6 straight chain alkenes + OH reactions

KAUST Repository

Khaled, Fathi; Badra, Jihad; Farooq, Aamir

2016-01-01

Alkenes are known to be good octane boosters and they are major components of commercial fuels. Detailed theoretical calculations and direct kinetic measurements of elementary reactions of alkenes with combustion radicals are scarce for C4 alkenes and they are practically absent for C5 and larger alkenes. The overall rate coefficients for the reaction of OH radical with 1-butene (CH CHCH CH, k ), 1-pentene (CH CHCH CH-CH, k ), cis/trans 2-pentene (CH CHCHCH CH, k and k ), 1-hexene (CH CHCH CH CH CH, k ) and cis/trans 2-hexene (CH CHCHCH CH CH, k and k ) were measured behind reflected shock waves over the temperature range of 833-1377K and pressures near 1.5atm. The reaction progress was followed by measuring mole fraction of OH radicals near 306.7nm using UV laser absorption technique. It is found that the rate coefficients of OH+trans-2-alkenes are larger than those of OH+cis-2-alkenes, followed by OH+1-alkenes. The derived Arrhenius expressions for the overall rate coefficients (in cm.mol.s) are:. kI=(4.83±0.03)104.T2.72±0.01.exp(940.8±2.9cal/molRT)(946K-1256K) + kII=(5.66±0.54)10-1.T4.14±0.80.exp(4334±227cal/molRT)(875K-1379K) + kIII=(3.25±0.12)104.T2.76±0.5.exp(1962±83cal/molRT)(877K-1336K) + kIV=(3.42±0.09)104.T2.76±0.5.exp(1995±59cal/molRT)(833K-1265K) + kV=(7.65±0.58)10-4.T5±1.exp(5840±175cal/molRT)(836K-1387K) + kVI=(2.58±0.06)106.T2.17±0.37.exp(1461±55cal/molRT)(891K-1357K) + kVII=(3.08±0.05)106.T2.18±0.37.exp(1317±38cal/molRT)(881K-1377K) +

Trichome morphology in Teucrium L. (Labiatae. A taxonomic review

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Navarro, Teresa

1999-12-01

Full Text Available The micromorphology of trichomes of 56 Teucrium L. species belonging to the 9 sections of the genus in the Mediterranean área was surveyed by scanning electrón microscopy (SEM of leaves, calyx, corolla and nutlets. 25 trichome types are described, 12 of them are new. Thin walled hairs are the exclusive type found in the corolla and are the most widespread type on the abaxial side of the leaves. Subsessile glandular hairs, 2-4-celled, are found on the nutlet and leaves of the semi-shrubby and paleoendemic species. The presence of short or elongated, generally adpressed simple thick-walled slighüy conical hairs provides an additional character to clarify the boundaries between sect. Chamedrys (Mill. Schreb, and sect. Polium (Mill. Schreb. Branched non-glandular hairs are confined to sect. Polium subsect Polium, except for the rare branched hair conical and thick-walled type found in Teucrium barbarum Jahand. & Maire (sect. Chamaedrys and T. heterophyllum L`Hér. from sect. Teucrium. This last section is well defined by the absence of simple slighüy conical thick-walled hairs and the glandular hairs in the corolla. Sect. Teucriopsis Benth, is of particular interest for the exclusive presence of branched and peltate glandular hairs on the nutlets surface. Sect. Chamedrys is a homogeneous group, distinguished from the other sections by an indumentum formed only by trichomes types evolved from the simple slighüy conical thick-walled hairs. This section overlaps, in the presence of glandular sub-sessile hair on the nutlets surface, with sects. Isotriodon Boiss, and sect. Polium subsect. Rotundifolia Cohén ex Valdés Berm. & Sánchez Crespo. The trichomes type of the calyx teeth, abaxial side of the leaf and latero-posterior corolla lobes can be used as a distinctive taxonomic character at specific and infra-specific level. This study supports Bentham's delimitaüon of sections with the addiüons subequently made by Boissier.La micromorfología de

The Effect of Fracture Filler Composition on the Parameters of Shear Deformation Regime

Science.gov (United States)

Pavlov, D.; Ostapchuk, A.; Batuhtin, I.

2015-12-01

RFBR (grant no. 13-05-00780). 1. Mair, K., K. M. Frye, and C. Marone (2002), J.Geophys.Res., 107(B10), 2219. 2. G.G. Kocharyan, V.K. Markov, A.A. Ostapchuk, and D.V. Pavlov (2014), Phys.Mes, 17(2), 123-133.

Ville et prostitution : rivales ou riveraines ? City and Prostitution: Rivals or Neighbours?

Directory of Open Access Journals (Sweden)

Catherine Deschamps

2008-04-01

Full Text Available Sous l’égide de l’Association des maires des grandes villes de France s’est tenue à Nantes, en juin 2003, la “Première rencontre française et internationale des professionnels de la ville” intitulée Les politiques urbaines face à la prosti­tution. Mobilisation des villes pour la répression de la traite aux fins d’exploi­tation sexuelle, la prévention et l’aide aux victimes. À partir des “actes” de cette rencontre, d’une enquête de terrain, d’une revue de la littérature et de la presse quotidienne française pour l’année 2003, cet article questionne la généa­logie contemporaine de l’association de la prostitution aux villes et les raisons qui, à tort ou à raison, motivent cette association. Parmi ces raisons, se cache une instrumentalisation des plus ambiguës de la “jeune prostituée étrangère”, associée à son corps défendant à l’image d’une traite mondiale, donc tenta­culaire. La rencontre nantaise est alors, à l’échelle de la ville, l’illustration, ou la répétition, de mécanismes plus généraux.Under the aegis of the Association of mayors of major French cities, the “First French and international meeting of city professionals” was held at Nantes, in June 2003, entitled Urban policies in dealing with prostitution. The mobilization of cities in the repression of slavery for purposes of sexual exploitation, prevention and aid to victims. Based on the “acts” of this meeting, a field survey, a review of the literature and the daily French press for the year 2003, this article questions the contemporary genealogy of the association of prostitution and cities, and the reasons which, rightly or wrongly, motivate that association. Among these reasons, is hidden a most ambiguous instrumentalization of the “young foreign prostitute”, associated despite herself with the image of a worldwide, and hence tentacular, slave trade. Thus the Nantes meeting is, on a city scale, the

Новые таксоны в роде Clinopodium L. (Lamiaceae. 2

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D. G. Melnikov

2016-06-01

Full Text Available В статье приводится описание пяти новых секций (sect. Umbraria, sect. Stellatocapillus, sect. Chortoranus, sect. Thymidulum, sect. Ellementha, пяти подсекций (subsect. Chinomelissa, subsect. Nepetoides, subsect. Baetica, subsect. Ascendentia, subsect. Menthofoliastrum и трех новых видов рода Clinopodium L. (C. krupkinae, C. gilanicum, C. syriacum, а также обнародование комбинаций: C. × alboviride, C. bulgaricum, C. largiflorum, C. nepetoides, C. spruneri, C. thessalum и заменяющего названия C. jordanii. Осуществлена лектотипификация Calamintha ascendens Jord., Calamintha chinensis Benth., Calamintha thessala Hausskn., Hedeoma micrantha Regel, Melissa candidissima Munby, Melissa umbrosa M. Bieb., Micromeria capitellata Benth., Satureja × alboviridis Faure et Maire.Ключевые слова: лектотипификация, номенклатурная комбинация, систематика, таксономия, новая секция, новый вид, Labiatae, Кавказ, Турция, Иран, Сирия.

Szaknyelvi nyelvhasználat és kommentelés Egy internetes szakmai honlap cikkeinek és fórumszövegeinek szemantikai-pragmatikai jellemzői

Directory of Open Access Journals (Sweden)

Sólyom, Réka

2015-10-01

Full Text Available Terminological language use and commenting: Semantic-Pragmatic features of a professional online website's articles and forum texts *** The paper analyses the semantic-pragmatic features of articles and related comments in a professional website called Menedzsment Fórum ('Management Forum', http://mfor.hu in a functional-cognitive framework. The goal of the analyses is to reveal those organising principles of meaning and understanding that prevail in articles and comments related to different topics of the website. With the help of some arbitrarily chosen examples, the present analysis shows that the occurrence of conceptual metaphors and metonymies, schemas, and conceptual integration, can foster understanding processes up to a great extent. During the analyses, semantic-pragmatic features of single-scope networks, double-scope networks will be studied, and a more complex expression considered as a multiple-scope network (digital Stone Age will be analysed and represented graphically within the framework of conceptual integration. *** A tanulmány egy internetes szakmai honlap, a Menedzsment Fórum (http://mfor.hu néhány cikkének és a cikkekhez kapcsolódó fórumszöveg-bejegyzéseknek szemantikai-pragmatikai jellemzőit elemzi funkcionális-kognitív keretben. Az elemzések célja azoknak a jelentés- és megértésszervező elveknek a feltárása, amelyek a különféle témájú cikkekben és kommentekben érvényesülnek. Jelen vizsgálat néhány önkényesen kiválasztott idézet elemzésével bemutatja, hogy a fogalmi metaforák és metonímiák, alakzatok, illetve a fogalmi integráció megjelenése a szövegekben nagymértékben segíti a megértési, befogadási folyamatokat. Az elemzések során sor kerül egy- és kétoldalú hálózatként megjelenő szavak, kifejezések elemzésére, valamint egy többoldalú hálózatként megjeleníthető, bonyolultabb felépítésű kifejezés (digitális kőkorszak szemantikai

Thermal and pressure stability of myrosinase enzymes from black mustard (Brassica nigra L. W.D.J Koch. var. nigra), brown mustard (Brassica juncea L. Czern. var. juncea) and yellow mustard (Sinapsis alba L. Subsp Maire) seeds

OpenAIRE

Okunade, O. A.; Ghawi, S. K.; Methven, Lisa; Niranjan, Keshavan

2015-01-01

This study investigates the effects of temperature and pressure on inactivation of myrosinase extracted from black, brown and yellow mustard seeds. Brown mustard had higher myrosinase activity (2.75 un/mL) than black (1.50 un/mL) and yellow mustard (0.63 un/mL). The extent of enzyme inactivation increased with pressure (600-800 MPa) and temperature (30-70 °C) for all the mustard seeds. However, at combinations of lower pressures (200-400 MPa) and high temperatures (60-80 °C), there was less i...

From field evaporation to focused ion beams

International Nuclear Information System (INIS)

Forbes, R.G.

2004-01-01

emission current, and the need in principle for modifications to Mair's theory of current/voltage characteristics. Recent (limited) progress in modelling the electrohydrodynamics of the LMIS, including the recognition that the equations for the time-dependent development of the conventional Taylor cone are self-similar. (author)

Evaluación de la producción de cuerpos fructíferos de cepas guatemaltecas del hongo comestible Rukoxil Tunay Che’ (Agrocybe cylindracea (DC.: Fr. Maire en diferentes sustratosEvaluation of the production of fruiting bodies of the

Directory of Open Access Journals (Sweden)

María del Carmen Bran

2014-10-01

Full Text Available En el presente estudio se determinó la producción de cuerpos fructíferos de cinco cepas nativas de Agrocybe cylindracea sobre tres sustratos y dos tratamientos térmicos, a través del porcentaje de eficiencia biológica y la medición del diámetro de los píleos. Se encontró que el mayor porcentaje de eficiencia biológica de las cepas en los sustratos evaluados fue 115.84 %, que correspondió al sustrato constituido por 29% paja de trigo mas 1% de harina de soya pasteurizado y obtenido por la cepa 58.01, la cual también produjo las mayores eficiencias biológicas en todos los sustratos evaluados. Al confrontar el porcentaje de eficiencia biológica en los diferentes sustratos, todas las cepas presentaron valores altos en el sustrato compuesto por 28% de paja de trigo, 1% harina de soya y CaCO3. Con respecto al diámetro de los cuerpos fructíferos, las cepas 58.01, 59.01, 60.01 y 638.08 produjeron píleos menores de 2 cm, entre 2-4 cm y mayores a 4.0 cm en los diferentes sustratos y tratamientos, excepto la cepa 59.01 que en el sustrato formulado con 29% de paja de trigo y 1% de harina de soya, solo produjo cuerpos fructíferos con píleos menores a 2 cm y entre 2-4 cm. En el análisis proximal de los basidiomas de las cepas evaluadas se obtuvo un alto porcentaje de proteínas, fibra cruda y carbohidratos, así como bajo porcentaje de grasas. Se recomienda que en futuras investigaciones o transferencia de tecnología a comunidades o entidades interesadas en el cultivo de este hongo, utilizar paja de trigo suplementada con harina de soya y como regulador de pH CaCO3, ya que en dicho sustrato se obtuvieron los mayores porcentajes de eficiencia biológica para la producción de cuerpos fructíferos de A. cylindracea.

Unusual isotopic composition of C-CO2 from sterilized soil microcosms: a new way to separate intracellular from extracellular respiratory metabolisms.

Science.gov (United States)

Kéraval, Benoit; Alvarez, Gaël; Lehours, Anne Catherine; Amblard, Christian; Fontaine, Sebastien

2015-04-01

The mineralization of organic C requires two main steps. First, microorganisms secrete exoenzymes in soil in order to depolymerize plant and microbial cell walls and release soluble substrates for microbial assimilation. The second step of mineralization, during which C is released as CO2, implies the absorption and utilization of solubilized substrates by microbial cells with the aim to produce energy (ATP). In cells, soluble substrates are carried out by a cascade of respiratory enzymes, along which protons and electrons are transferred from a substrate to oxygen. Given the complexity of this oxidative metabolism and the typical fragility of respiratory enzymes, it is traditionally considered that respiration (second step of C mineralization process) is strictly an intracellular metabolism process. The recurrent observations of substantial CO2 emissions in soil microcosms where microbial cells have been reduced to extremely low levels challenges this paradigm. In a recent study where some respiratory enzymes have shown to function in an extracellular context in soils, Maire et al. (2013) suggested that an extracellular oxidative metabolism (EXOMET) substantially contributes to CO2 emission from soils. This idea is supported by the recent publication of Blankinship et al., 2014 who showed the presence of active enzymes involved in the Krebs cycle on soil particles. Many controversies subsist in the scientific community due to the presence of non-proliferating but morphologically intact cells after irradiation that could substantially contribute to those soil CO2 emissions. To test whether a purely extracellular oxidative metabolism contribute to soil CO2 emissions, we combined high doses of gamma irradiations to different time of soil autoclaving. The presence of active and non-active cells in soil was checked by DNA and RNA extraction and by electronic microscopy. None active cells (RNA-containing cells) were detectable after irradiation, but some morphological

Readiness for Delivering Digital Health at Scale: Lessons From a Longitudinal Qualitative Evaluation of a National Digital Health Innovation Program in the United Kingdom.

Science.gov (United States)

Lennon, Marilyn R; Bouamrane, Matt-Mouley; Devlin, Alison M; O'Connor, Siobhan; O'Donnell, Catherine; Chetty, Ula; Agbakoba, Ruth; Bikker, Annemieke; Grieve, Eleanor; Finch, Tracy; Watson, Nicholas; Wyke, Sally; Mair, Frances S

2017-02-16

, barriers to mainstreaming remain. Our findings suggest greater investment in national and local infrastructure, implementation of guidelines for the safe and transparent use and assessment of digital health, incentivization of interoperability, and investment in upskilling of professionals and the public would help support the normalization of digital health. These findings will enable researchers, health care practitioners, and policy makers to understand the current landscape and the actions required in order to prepare the market and accelerate uptake, and use of digital health and wellness services in context and at scale. ©Marilyn R Lennon, Matt-Mouley Bouamrane, Alison M Devlin, Siobhan O'Connor, Catherine O'Donnell, Ula Chetty, Ruth Agbakoba, Annemieke Bikker, Eleanor Grieve, Tracy Finch, Nicholas Watson, Sally Wyke, Frances S Mair. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 16.02.2017.

A javítási műveletek jelöltségi hipotézise

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Zsuzsanna Németh

2014-12-01

Full Text Available The markedness hypothesis of repair operations In this paper, using conversation analysis, I propose a model describing the technology of four repair operations, namely, recycling, replacement, insertion, and aborting relative to each other on the basis that they inherently halt the progressivity of the current turn-at-talk. As violating the preference for progressivity is a marked usage, interpreting the property of halting progressivity as a system of binary features in the case of the four repair operations enables us to apply the theory of markedness to describe the technology of the repair operations relative to each other. Testing the model has been possible only in an indirect way by setting up a sub-hypothesis. I have argued that not only their functions but also their degree of markedness plays a role in the selection of repair operations employed in carrying out the same action. I have tested the sub-hypothesis on a Hungarian corpus. The results support the hypothesis. A tanulmány a konverzációelemzés elméleti keretében négy javítási művelet, az ismétlés, a beszúrás, a csere és a törlés technológiáját hasonlítja össze kísérletet téve egy olyan modell létrehozására, amely a javítási műveletek jelöltségét feltételezi. Ennek alapja, hogy a spontán társalgások során alkalmazott javítási jelenségek felfüggesztik a folyamatban levő forduló, és ezáltal a folyamatban levő cselekvés előrehaladását. Mivel a progresszivitás fenntartása általános preferencia a társalgásban, megszakítása jelölt nyelvhasználatot eredményez, amelyet a négy művelet esetében három bináris jegy rendszereként értelmezhetünk (retrospektivitás, redundancia, nem megfelelő szegmentum. A modell tesztelése egy magyar nyelvű korpuszon történt egy szub-hipotézis segítségével, amelynek lényege, hogy az egyazon cselekvés során alkalmazott javítási műveletek kiválasztásában funkcióik mellett

Ultra-Pure Water and Extremophilic Bacteria interactions with Germanium Surfaces

Science.gov (United States)

Sah, Vasu R.

Supported by a consortium of semiconductor industry sponsors, an international "TIE" project among 5 National Science Foundation (NSF) Industry/university Cooperative Research Centers discovered that a particular extremophilic microbe, Pseudomonas syzygii, persists in the UltraPure Water (UPW) supplies of chip fabrication facilities (FABs) and can bio-corrode germanium wafers to produce microbe-encased optically transparent crystals. Considered as potentially functional "biochips", this investigation explored mechanisms for the efficient and deliberate production of such microbe-germania adducts as a step toward later testing of their properties as sensors or switches in bioelectronic or biophotonic circuits. Recirculating UPW (Ultra-Pure Water) and other purified water, laminar-flow loops were developed across 50X20x1mm germanium (Ge) prisms, followed by subsequent examination of the prism surfaces using Multiple Attenuated Internal Reflection InfraRed (MAIR-IR) spectroscopy, Contact Potential measurements, Differential Interference Contrast Light Microscopy (DICLM), Scanning Electron Microscopy (SEM), Energy Dispersive X-Ray Analysis (EDS), and Electron Spectroscopy for Chemical Analysis (ESCA; XPS). P. syzygii cultures originally obtained from a working FAB at University of Arizona were successfully grown on R2A minimal nutrient media. They were found to be identical to the microbes in stored UPW from the same facility, such microbes routinely capable of nucleation and entrapment within GeO2 crystals on the Ge flow surfaces. Optimum flow rates and exposure times were 1 ml/minute (3.2 s-1 shear rate) for 4 days at room temperature, producing densest crystal arrays at the prism central zones 2-3 cm from the flow inlets. Other flow rates and exposure times have higher shear rate which induces a different nucleation mechanism and saturation of crystal formation. Nucleation events began with square and circular oxide deposits surrounding active attached bacteria

Digital Support Interventions for the Self-Management of Low Back Pain: A Systematic Review.

Science.gov (United States)

Nicholl, Barbara I; Sandal, Louise F; Stochkendahl, Mette J; McCallum, Marianne; Suresh, Nithya; Vasseljen, Ottar; Hartvigsen, Jan; Mork, Paul J; Kjaer, Per; Søgaard, Karen; Mair, Frances S

2017-05-21

-1343 participants per study) and varied considerably in the nature and delivery of the interventions, the duration/definition of LBP, the outcomes measured, and the effectiveness of the interventions. Participants were generally white, middle aged, and in 5 of 6 RCT reports, the majority were female and most reported educational level as time at college or higher. Only one study reported between-group differences in favor of the digital intervention. There was considerable variation in the extent of reporting the characteristics, components, and theories underpinning each intervention. None of the studies showed evidence of harm. The literature is extremely heterogeneous, making it difficult to understand what might work best, for whom, and in what circumstances. Participants were predominantly female, white, well educated, and middle aged, and thus the wider applicability of digital self-management interventions remains uncertain. No information on cost-effectiveness was reported. The evidence base for interactive digital interventions to support patient self-management of LBP remains weak. ©Barbara I Nicholl, Louise F Sandal, Mette J Stochkendahl, Marianne McCallum, Nithya Suresh, Ottar Vasseljen, Jan Hartvigsen, Paul J Mork, Per Kjaer, Karen Søgaard, Frances S Mair. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 21.05.2017.

Rising CO2 widens the transpiration-photosynthesis optimality space

Science.gov (United States)

de Boer, Hugo J.; Eppinga, Maarten B.; Dekker, Stefan C.

2016-04-01

). Measurements of gs and V cmax were obtained with a portable photosynthesis system. Our empirical results support the prediction that the V cmax:gs-ratio increases with higher CO2 in both Solanum genotypes. The 'dry' genotype revealed a significantly higher Huber value and lower V cmax than the 'wet' genotype at each CO2 growth level. Moreover, we found that the down-regulation of V cmax under higher CO2 was stronger in the 'dry' genotype than in the 'wet' genotype, whereas no change in the Huber value was observed between CO2 levels. Consistent with the theoretical trade-off between the resulting costs of transpiration and photosynthesis, we found that the CO2-induced increase in the V cmax:gs-ratio was stronger in the 'wet' genotype than in the 'dry' genotype. Given the divergence of V cmax:gs relationships observed, we conclude that rising atmospheric CO2 may widen the V cmax - gs optimality space available for plants to achieve an optimal trade-off between photosynthesis and transpiration. References Prentice, I. C., Dong, N., Gleason, S. M., Maire, V. and Wright, I. J.: Balancing the costs of carbon gain and water transport: testing a new theoretical framework for plant functional ecology, Ecol. Lett., 17(1), 82-91, 2014.

How established companies can master disruptive innovation like startups? Achieving innovation excellence and disruptive ability = Miként tudnak az érett vállalatok startupok módjára megszakító innovációkat létrehozni? Út az innovációs kiválóság és a diszrupciós képesség felé

OpenAIRE

Kristóf, Péter

2016-01-01

Emerging exponential technologies empower entrepreneurs to create a world of abundance. For established companies it implicates that if they are not the ones creating this abundance, somebody else will, by disrupting their technology and market. In order to keep pace they have to learn how to pick up and apply exponential mindset and master disruptive innovation like startups – even within their established organizations.

Proceedings of the 2011 hydrocarbon annual days - Innovation, technological and human challenges

International Nuclear Information System (INIS)

2011-01-01

This document gathers the available presentations (slides) given at the 2011 issue of the annual hydrocarbon days. The conference comprises 14 workshops and 5 plenary sessions dealing with: - Plenary 1 - oil and gas and the evolution of the world energy landscape: The new geopolitical energy landscape (Lesourne, J.); Macondo and Fukushima: what challenges for the industry and for Total? (Mosconi, J.J.); Natural gas: energy of the 21. century? (Bensasson, B.); - Workshop 1 - innovation in modeling, computer science and calculations: Tools at the engineering service - 3D visualisation mock-ups (Hoffert, J.L.; Bouget, F.); Basins modelling (Facon, J.); 'OCEAN' computer platform and calculation modules development (Dury, V.); - Workshop 2 - source rock hydrocarbons: Exploration-production (B. Courme); Aquifers monitoring technology (Lallier, S.); Hydraulic fracturing of schists (Faucompret, N.); - Workshop 3 - research, universities and industries, the innovating process: presentation of ANCRE actions - situation of research (Goffe, B.); Artificial photosynthesis - using solar energy for hydrogen and fuels production (Artero, V.); Partnership and competitiveness (Valadier, L.); - workshop 4 - marine innovations, new ships: new building ships for ultra-deep offshore and big pipelines (Ardavanis, K.); The Seven Borealis, a World-Class Strategic Enabler (Bost, F.); Application of innovation utilizing the Skandi Arctic through the use of the Pipeline Repair System (PRS) and the Personal Diving Equipment (PDE) (Grosjean, P.); - Workshop 5 - innovative Subsea equipments: Subsea: Way to Future - Fully Autonomous Plant (Riviere, L.); The 2. Generation DC All-Electric Subsea Production Control System (Van der Akker, J.); The power distribution module: an essential component in the submarine production chain (Eschbach, J.L.); Reeled installation of EHTF - Electrically Heat Traced Pipe-in-Pipe (Mair, J.); - Workshop 6 - seismic imaging: Towed streamer seismic strategies for sub

Ferdinand Buisson (1841-1932 educador e pacifista: as influências libertárias de James Guillaume e Paul Rodin

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Martine Brunet

2012-07-01

dans le domaine religieux, politique et pédagogique; ces trois domaines se sont interpénétrés tout au long de sa vie. Très tôt il entre dans la vie publique et il se fait remarquer par des prises de positions radicales contre la guerre en participant aux premiers congres de Ia Ligue de la Paix et de la Liberté en Suisse. Des Ia chute de l'Empire, il participe à Ia vie poli tique du 17° arrondissement de Paris, dont l' adjoint au maire est l'anarchiste Benoit Malon. Il s'engage dans Ia Garde Nationale, il participe activement aux initiatives politiques et sociales de Ia municipalité, il est cofondateur d'un journal anarchiste Lu République des Travailleurs avec Aristide Rey, les freres Reclus et Benoit Malon. C'est dans Ia tourmente de la guerre, d'un Siege de Paris qu'il crée un orphelinat. Cet établissement lai'que reçoit des subsides de l'Internationale et donne une éducation intégrale issue des idées de I'anarchiste Paul Robin. Apres Ia défaite de la Commune, l'orphelinat est transféré à Cempuis dans l’Oise. En 1879, Ferdinand Buisson nommé directeur de l'enseignement primaire fait appel à Paul Robin pour diriger l'orphelinat selon ses méthodes libertaires. L'établissement et son directeur sont pris violemment à partis par les catholiques réactionnaires. l'expérience de Cempuis est finie en 1894. Mots-clé: éducation libertaire, liberté, internationale. 

Trace element mobility at the slab-mantle interface: constraints from "hybrid

Science.gov (United States)

Marocchi, M.; Tropper, P.; Mair, V.; Bargossi, G. M.; Hermann, J.

2009-04-01

the phlogopite-rich zone suggests that the trace element signature of subduction zone fluids may be fractionated in this zone. The progressive depletion in some trace elements (LREE and LILE) and enrichment in Li from the gneiss towards the peridotite suggests a strong influence of bulk composition on the trace element budget of hydrous minerals. Since these metasomatic zones can be representative of the processes occurring at the slab-mantle interface, we can infer that metasomatic reactions between slab-derived fluids and ultramafic mantle wedge will follow a specific series of reactions and create mineral zones similar to those observed in this study. Despite the mobility of many elements, in the trace element profiles for amphibole and phlogopite across the different zones, we observe a rapid decrease even of the "fluid mobile" element contents within the reaction zone. With the exception of Li, we assist to an abrupt decrease of most of trace element concentrations going towards the peridotite side contact. Thus, according to the present study, it is not likely that the "crustal trace element signature" (i.e. LILE and LREE-enriched) could be able to travel far into the mantle. Our results further favour the evidence that the primary composition of subduction zone fluids reaching the source region of arc magmas is substantially modified by metasomatic reactions occurring in the mantle wedge. Furthermore, we underline that metasomatic rocks such as those observed at Mt. Hochwart are potentially able to transport H2O and other trace elements to greater depths in subduction zones. References: Marocchi M, Hermann J, Morten L (2007)-Lithos 99: 85-104. Marocchi M, Mair V, Tropper P, Bargossi GM (2009)-Mineral Petrol, in press Miller DP, Marschall RH, Schumacher JC (2009)- Lithos 107: 53-67. Scambelluri M, Hermann J, Morten L, Rampone E (2006)- Contrib Mineral Petrol 151:372-394. Spandler CJ, Hermann J, Faure K, Mavrogenes JA, Arculus RJ (2008)- Contrib Mineral Petrol

Influence of elastomeric seal plate surface chemistry on interface integrity in biofouling-prone systems: Evaluation of a hydrophobic "easy-release" silicone-epoxy coating for maintaining water seal integrity of a sliding neoprene/steel interface

Science.gov (United States)

Andolina, Vincent L.

Attenuated Internal Reflection (MAIR-IR) and Microscopic Infrared Spectroscopy for organic surface compositional details, light microscopy for wear area quantification, and profilometry for surface roughness estimation and wear depth quantification. Pin-on-disc dynamic Coefficient of Friction (CoF) measurements provided data relevant to forecasts of seal integrity in dry, wet and biofouling-influenced sliding contact. Actual wear of neoprene seal material against uncoated and coated steel surfaces, wet and dry, was monitored after both rotary and linear cyclic wear testing, demonstrating significant reductions in elastomer wear areas and depths (and resultant volumes) when the coating was present. Coating the steel eliminated a 270% increase in neoprene surface area wear and an 11-fold increase in seal abrasive volume loss associated with underwater rusting in rotary experiments. Linear testing results confirm coating efficacy by reducing wear area in both loading regimes by about half. No coating delamination was observed, apparently due to a differential distribution of silicone and epoxy ingredients at the air-exposed vs. steel-bonded interfaces demonstrated by IR and EDS methods. Frictional testing revealed higher Coefficients of Friction (CoF) associated with the low-speed sliding of Neoprene over coated rather than uncoated steel surfaces in a wet environment, indicating better potential seal adhesion between the hydrophobic elastomer and coating than between the elastomer and intrinsically hydrophilic uncoated steel. When zebra mussel biofouling debris was present in the articulating joints, CoF was reduced as a result of a water channel path produced between the articulating surfaces by the retained biological matter. Easier release of the biofouling from the low-CST coated surfaces restored the seal integrity more rapidly with further water rinsing. Rapid sliding diminished these biofouling-related differences, but revealed a significant advantage in reducing the Co

Villes indiennes sous tutelle ? Une réflexion sur les échelles de gouvernance à partir des cas de Mumbai et Hyderabad

Directory of Open Access Journals (Sweden)

Loraine Kennedy

2011-11-01

Full Text Available De manière croissante, les décideurs politiques en Inde perçoivent le rôle crucial des villes dans l’économie nationale et les politiques actuelles menées par les États régionaux reflètent cette prise de conscience. Basée sur les cas proches, sans être entièrement comparables, d’Hyderabad et de Mumbai, cette recherche montre que les gouvernements des États ont adopté des stratégies de croissance centrée sur la ville, à l’instar des tendances internationales. Cela soulève la question du rééchelonnage des instances décisionnelles et de l’essor de l’émergence politique des régions métropolitaines. Après l'examen détaillé des stratégies de développement économique et urbain adoptées à Mumbai et à Hyderabad, cet article défend l’idée que les grandes villes indiennes n’ont pas une position suffisamment solide pour revendiquer un poids politique vis-à-vis de leur gouvernement régional et ne sont pas armées pour s'engager sérieusement dans la construction d’une action collective à l’échelle métropolitaine. Il convient de souligner cette déconnexion paroxystique entre les fonctions politiques et économiques, dans la mesure où cela marque une différence de degré avec l’expérience européenne récente. La subordination politique des collectivités locales urbaines en Inde est aggravée par le caractère traditionnellement centralisateur des institutions politiques, la faiblesse relative des institutions locales de gouvernance (en termes de mandat et de ressources fiscales, l'absence de maires puissants et la quasi-inexistence de statut politique de la plupart des régions métropolitaines. En outre, échafauder un plan stratégique qui tienne compte de la croissance économique, de la justice sociale et de l’environnement est une tâche herculéenne, particulièrement dans une société plurielle. Ainsi, dans les deux villes les processus en cours sont conflictuels et empreints de

Mathematical and numerical aspects of low mach number flows

Energy Technology Data Exchange (ETDEWEB)

Schochet, St.; Bresch, D.; Grenier, E.; Alazard, T.; Gordner, A.; Sankaran, V.; Massot, M.; Sery, R.; Pebay, P.; Lunch, O.; Mazhorova, O.; Turkel, O.E.; Faille, I.; Danchin, R.; Allain, O.; Birken, P.; Lafitte, O.; Kloczko, T.; Frick, W.; Bui, T.; Dellacherie, S.; Klein, R.; Roe, Ph.; Accary, G.; Braack, M.; Picano, F.; Cadiou, A.; Dinescu, C.; Lesage, A.C.; Wesseling, P.; Heuveline, V.; Jobelin, M.; Weisman, C.; Merkle, C.

2004-07-01

diphasic system (S. DELLACHERIE); a preconditioning technique for biphasic flows with interfaces (C. DINESCU, B. LEONARD, C. HIRSCH); two models for the simulation of multiphase flows in oil and gas pipelines (I. FAILLE); physics and insects require compressible low Mach number flow (W. FRICK); multigrid for low mach number flows including acoustic modes (A. GORDNER); adaptive finite element method for low mach number flows (V. HEUVELINE); using multiple scales asymptotics in the construction of low Mach number numerics (R. KLEIN); a matrix-free implicit method for flows at all speeds (T. KLOCZKO, A. BECCANTINI, C. CORRE); linear growth rate for the quasi-isobaric ablation front model of Kull-Anisimov (O. LAFITTE); augmented projection methods for incompressible and dilatable flows (J. CLATCHE, M. JOBELIN, C. LAPUERTA, P. ANGOT, B. PIAR); a numerical accuracy study for level set formulations (A.C. LESAGE, O. ALLAIN, A. DERVIEUX) 3D computer simulation of convective instability in the multicomponent solution (O. MAZHOROVA, V. KOLMYCHKOV, Y. POPOV, P. BONTOUX, M. El GANAOUI); multicomponent reactive flows: symmetrization and the low Mach number limit (M. MASSOT, V. GIOVANGIGLI); computation of low mach number flows with a generalized Gibbs relation (C.L. MERKLE, V. SANKARAN, D. LI); a Mach-uniform pressure correction algorithm (K. NERINCK, J. VIERENDEELS, E. DICK); application of Turkel preconditioning method in external free convection and incompressible flows (T.H. NGUYEN-BUI, B. DUBROCA, P.H. MAIRE); a half-explicit, non-split projection method for low mach number flows (P.P. PEBAY, H. N. NAJIM, J. POUSIN); combustion in low Mach number isotropic turbulence (F. PICANO, P. GUALTIERI, B. FAVINI); calculation of low Mach number acoustics: a comparison of MPV, EIF and linearized Euler equations (S. ROLLER, T. SCHWARTKOFF, M. DUMBSER, C.D. MUNZ) comparison of pressure-based and density-based methods for low Mach number CFD computations (V. SANKARAN, C. MERKLE); the

Integración y desarrollo de la región fronteriza peruano ecuatoriana: entre el discurso y la realidad, una visión local

Directory of Open Access Journals (Sweden)

2002-01-01

Full Text Available INTÉGRATION ET DÉVELOPPEMENT DE LA RÉGION FRONTALIÈRE PÉRUANO-ÉQUATORIENNE: ENTRE LE DISCOURS ET LA RÉALITÉ, UNE VISION LOCALE Dans la première partie de cet article nous analyserons les textes des accords de paix, signés entre le Pérou et l’Équateur en 1998, pour indiquer comment ces documents tendent, en reconnaissant la frontière, à la rendre perméable pour qu’elle ne constitue pas un obstacle à l’actuel processus de globalisation. Dans la seconde partie, dans une perspective historique de quelques trente cinq ans, nous indiquerons les fractures, les différences et les complémentarités, naturelles et sociales, qui rendent compte d’une complexité régionale que ces documents ne reconnaissent pas. Dans la troisième partie nous décrirons la situation qui peut être observée aux trois nouveaux passages frontaliers, en prêtant attention à l’environnement, à la production, aux voies de communication et aux échanges, dans le but de mettre en évidence, à l’échelle locale, les impacts du Plan Binational de Développement de la Région Frontalière. Finalement dans la quatrième partie, sur la base d’entrevues avec des maires et leurs administrés, nous essayerons de comparer le discours officiel avec la réalité qui se perçoit et se vit localement, à fin de formuler quelques questions en rapport avec les problèmes et les possibilités d’intégration et de développement régional. En la primera parte de este artículo analizaremos los textos de los acuerdos de paz firmados entre Perú y Ecuador en 1998, para indicar de qué manera estos documentos tienden, reconociendo la frontera, a volverla permeable para que no constituya un obstáculo al actual proceso de globalización. En la segunda parte, con una perspectiva histórica de unos treinta y cinco años, indicaremos las fracturas, diferencias y complementariedades, naturales y sociales, que rinden cuenta de una complejidad regional que desconocen estos

Foreword

Science.gov (United States)

Boutron, Claude; Ferrari, Christophe

2003-05-01

Informatique, Biologie et Médecine, et Sciences de la Terre et de l'Univers. Il y a deux grandes Universités Scientifiques de renommée internationale: l'Université Joseph Fourier (UJF) et l'Institut National Polytechnique de Grenoble (INPG). Il y a aussi d'importants laboratoires de différents organismes publics français et européen comme le Commissariat à l'Énergie Atomique (CEA), le Centre National de la Recherche Scientifique (CNRS), l'Institut Laue Langevin (ILL), l'European Synchrotron Radiation Facility (ESRF) et l'Institut de Radio-Astronomie Millimètrique (IRAM). C'est aussi le lieu d'implantation de nombreuses sociétés de haute technologie comme Hewlett Packard, ST Microelectronics, Schneider Electric and SGS-Thomson. Il a à Grenoble une longue tradition de recherches dans le domaine des métaux lourds dans l'environnement, notamment au Laboratoire de Glaciologie et Géophysique de l'Environnement et au Laboratoire de Géophysique Interne et Tectonophysique. Ces deux volumes regroupent les articles issus de communication présentées aussi bien au cours des sessions orales que des sessions posters. Ces articles sont classés selon l'ordre alphabétique du nom de famille du premier auteur. Nous remercions vivement les auteurs pour l'excellente qualité de ces articles. Nous remercions aussi tout particulièrement Isabelle Houlbert et Laurence Castagné pour leur collaboration. Nous aimerions aussi remercier les membres du comité d'organisation ainsi que Jerome Nriagu (organisateur de la 11e conférence) pour l'aide apportée à l'organisation de cette conférence. Nous remercions aussi tout spécialement Christine Echevet qui n'a pas ménagé ses efforts pour faire de cette conférence un succés, ainsi que de nombreux collègues du Laboratoire de Glaciologie et Géophysique de l'Environnement, en particulier Jocelyne Roquemora. Nous tenons également à remercier le Président de Grenoble Alpes Métropole et le Maire de la Ville de Grenoble pour leur

Greenland plays a large role in the gloomy picture painted of probable future sea-level rise

Science.gov (United States)

Hanna, Edward

2012-12-01

very coarse at 5.625° latitude/longitude resolution. There appears to be a cancelling out of errors in LOVECLIM, where its climate sensitivity seems quite low (in comparison with other models) but the simulated enhanced high-latitude warming—often termed Arctic amplification and evident in observed climate data for the last 30 years—is quite high. It would be good to include precipitation as well as temperature changes when modelling the future response of glaciers, even though the former is likely to be less important. I do not agree that uncertainties in climate sensitivity can be adequately accounted for by varying boundary and initial conditions in ensembles of models, as all of the model simulations may be systematically biased due to some physical effect that is improperly considered—or unrepresented—by all of the models, but this is a widely used technique and probably the best that can be done here. Despite these caveats, Goelzer et al 's (2012) results will undoubtedly prove useful for the Intergovernmental Panel on Climate Change (IPCC)'s upcoming Fifth Assessment Report due to be released in 2014. The key challenge remains to further improve the individual components of the Earth system model, especially those concerning ice-sheet dynamics. Acknowledgments EH thanks Ben Brock, Amy Jowett and Andrew Sole for useful editorial suggestions to the text. References Barletta V R, Sørensen L S and Forsberg R 2012 Variability of mass changes at basin scale for Greenland and Antarctica Cryosp. Discuss. 6 3397-446 Bartholomew I, Nienow P, Sole A, Mair D, Cowton T and King M A 2011 Seasonal variations in Greenland ice sheet motion: inland extent and behaviour at higher elevations Earth Planet. Sci. Lett. 307 271-8 Goelzer H, Huybrechts P, Raper S C B, Loutre M -F, Goosse H and Fichefet T 2012 Millennial total sea-level commitments projected with the Earth system model of intermediate complexity LOVECLIM Environ. Res. Lett. 7 045401 Hanna E, Huybrechts P

An Integrated Biochemistry Laboratory, Including Molecular Modeling

Science.gov (United States)

Hall, Adele J. Wolfson Mona L.; Branham, Thomas R.

1996-11-01

' work; point out any problems in organization or grammar; and suggest the steps necessary to complete the paper. They then go over the peer review form with the writer, referring any questions or disagreements to the instructor. It is most helpful if the instructor can also read and comment on the draft. General comments on the level of detail included and any problems with the reasoning come more appropriately from the instructor than from peers. The paper is then revised and handed in on the following week. The final draft is accompanied by a summary of revisions and copies of all peer reviews. Students are graded on peer reviews and summaries of revisions and cover letters, as well as on the final paper. Acknowledgments The molecular modeling workstations and associated software were purchased with funding from NSF, Instrumentation and Laboratory Improvement program, grant DUE-9350843 to AJW, with matching funds from Wellesley College. Some of the equipment for protein purification was funded by a grant from the Howard Hughes Medical Institute to Wellesley College. The authors are grateful to Paul Reisberg for helpful discussions in the early stages of this project and to Margaret Merritt for a critical review of the manuscript. Literature Cited 1. Blake, C. C. F.; Jonhson, L. N.; Mair, G. A.; North, A. C. T.; Phillips. D. C.; Sarma, V. R. Proc. Roy. Soc. London Ser. B 1967, 167, 378 - 388. 2. Hendrickson, H. S.; Giannini, J. L.; Bergstrom, J. P.; Johnson, S. N.; Leland, P. A. Biochem. Educ. 1995, 23, 14 - 17. 3. Miranker, A., Robinson, C. V.; Radford, S. E.; Aplin, R. T.; Dobson, C. M. Science 1993, 262, 896 - 900. 4. Turner, M. A.; Howell, P. L. Prot. Sci. 1995, 4, 442 - 449. 5. Radmacher, M.; Fritz, M.; Hansma, H. G.; Hansma, P. Science 1994, 265, 1577 - 1579. 6. Shugar, D. Biochim. Biophys. Acta 1952, 8, 302 - 309. 7. Bradford, M. M. Anal. Biochem. 1976, 72, 248 - 254. 8. Strang, R. H. C. In Practical Biochemistry for Colleges; Wood, E. J., Ed.; Pergamon: Oxford