WorldWideScience

Sample records for kirkilas urges expediency

  1. Kirkilas threatens to quit / Kimberly Kweder

    Index Scriptorium Estoniae

    Kweder, Kimberly

    2007-01-01

    Leedu peaminister Gediminas Kirkilas ähvardas loobuda ametikohast, kui parlament hääletab seaduseeelnõu poolt, mis lubab välja anda sadade miljonite littide väärtuses maksmata pensione, destabiliseerides riigi majandust

  2. Adamkus, Kirkilas take Lithuania's energy case to East European partners

    Index Scriptorium Estoniae

    2008-01-01

    Euroopa tuumaenergia foorumil esinedes palusid Leedu peaminister Gediminas Kirkilas ja president Valdas Adamkus EL-i partneritel taas kaaluda Ignalina tuumajaama lahtiolekuaja pikendamist. Hispaania ja Tšehhi esindaja ning Jose Manuel Barroso arvamused

  3. Kirkilas demands bureaucrats get to bottom of capricious milk market

    Index Scriptorium Estoniae

    2008-01-01

    Leedu peaminister Gediminas Kirkilas nõuab Leedu põllumajandusministeeriumilt ja konkurentsiametilt meetmeid riigi piimaturu stabiliseerimiseks. Piima kokkuostuhind on langenud, samas kui jaemüügihinnad jäid samaks või tõusid

  4. Blast tests of expedient shelters in the DICE THROW event

    International Nuclear Information System (INIS)

    Kearny, C.H.; Chester, C.V.

    1978-03-01

    To determine the worst blast environments that eight types of expedient shelters can withstand, we subjected a total of 18 shelters to the 1-kiloton blast effects of Defense Nuclear Agency's DICE THROW main event. These expedient shelters included two Russian and two Chinese types. The best shelter tested was a Small-Pole Shelter that had a box-like room of Russian design with ORNL-designed expedient blast entries and blast doors added. It was undamaged at the 53-psi peak overpressure range; the pressure rise inside was only 1.5 psi. An unmodified Russian Pole-Covered Trench Shelter was badly damaged at 6.8 psi. A Chinese ''Man'' Shelter, which skillfully uses very small poles to attain protective earth arching, survived 20 psi, undamaged. Two types of expedient shelters built of materials found in and around most American homes gave good protection at overpressures up to about 6 psi. Rug-Covered Trench Shelters were proved unsatisfactory. Water storage pits lined with ordinary plastic trash bags were proven practical at up to 53 psi, as were triangular expedient blast doors made of poles

  5. Expedient

    Directory of Open Access Journals (Sweden)

    Fernando de Assis Rodrigues

    2017-07-01

    Full Text Available Expedient of Volume 3, Issue 1 from the year 2017EDITORIAL STAFFEditorsDiana Vilas Boas Souto AleixoFernando de Assis RodriguesEditorial ComissionDiana Vilas Boas Souto AleixoFernando de Assis RodriguesRicardo César Gonçalves Sant’AnaExecutive ComissionPedro Henrique Santos BisiAd hoc peer reviewersAna Carolina Simionato, Universidade Federal de São Carlos (UFSCarDiana Vilas Boas Souto Aleixo, Universidade Estadual Paulista (UNESPElaine Parra Affonso, Faculdade de Tecnologia de Presidente Prudente (FATEC - Universidade Estadual Paulista (UNESPElvio Gilberto da Silva, Universidade do Sagrado Coração (USCFábio Mosso Moreira, Universidade Estadual Paulista (UNESPThais Batista Zanineli, Universidade Estadual de Londrina (UELText reviewersDiana Vilas Boas Souto Aleixo, Universidade Estadual Paulista (UNESPElizabete Cristina de Souza Aguiar Monteiro (UNESP

  6. Expedient

    Directory of Open Access Journals (Sweden)

    Fernando de Assis Rodrigues

    2018-05-01

    Full Text Available ExpedientElectronic Journal Digital Skills for Family Farming (RECoDAFISSN (electronic – 2448-0452Expedient of Volume 4, Issue 1, January – June of year 2018 EDITORIAL BOARDHead EditorFernando de Assis Rodrigues – São Paulo State University (UNESP, BrazilEditorial BoardAlfredo Bonini Neto, São Paulo State University (UNESP, BrazilAna Carolina Simionato, Federal University of São Carlos (UFSCar, BrazilCristian Berrío-Zapata, Federal University of Pará (UFPA, BrazilElaine Parra Affonso, São Paulo State Technological College (FATEC - São Paulo State University (UNESP, BrazilFernando de Assis Rodrigues, São Paulo State University (UNESP, BrazilMaria Elisabete Catarino, State University of Londrina (UEL, BrazilMaría Laura Foradori, National University of Córdoba (UNC, ArgentinaPascal Aventurier, Institut de Recherche pour le Développement (IRD, FranceRicardo César Gonçalves Sant’Ana, São Paulo State University (UNESP, BrazilExecutive ComissionFábio Mosso Moreira, São Paulo State University (UNESP, BrazilPedro Henrique Santos Bisi, São Paulo State University (UNESP, BrazilAd hoc peer reviewers of this issueAna Carolina Simionato, Federal University of São Carlos (UFSCar, BrazilCristian Berrío-Zapata, Federal University of Pará (UFPA, Brazil Cristiane Hengler Corrêa Bernardo, São Paulo State University (UNESP, BrazilDiana Vilas Boas Souto Aleixo, Faculdade de Filosofia e Ciências, São Paulo State University (UNESP, BrazilElizabete Cristina de Souza de Aguiar Monteiro, Faculdade de Filosofia e Ciências, São Paulo State University (UNESP, Brazil Elvio Gilberto da Silva, Sacred Heart University (USC, BrazilFábio Mosso Moreira, São Paulo State University (UNESP, BrazilJacquelin Teresa Camperos Reyes, São Paulo State University (UNESP, BrazilLarissa Pavarini Luz, São Paulo State Technological College (FATEC, BrazilMaria Elisabete Catarino, State University of Londrina (UEL, BrazilPascal Aventurier, Institut de

  7. Analysis of the Expediency of Switching to Accounting Outsourcing

    Directory of Open Access Journals (Sweden)

    Liakhovych Halyna І.

    2017-12-01

    Full Text Available The aim of the article is to justify the methodology for analysis of the expediency of switching to accounting outsourcing. Based on considering scientific papers, approaches to analyzing the expediency of switching to accounting outsourcing are generalized; special attention is paid to analyzing transaction costs of accounting outsourcing, which under current conditions are one of the defining quantitative criteria for choosing this form of organization of accounting. The choice of the type of accounting outsourcing (full or partial for various groups of enterprises (micro-enterprises, small and medium-sized, large ones is justified. There determined the sequence of analyzing the expediency of switching to accounting outsourcing that implies identification of the areas of accounting for transferring; selection of an outsourcer; assessment of risks associated with reliability of the outsourcer. Prospects for further research are the issue of analyzing the effectiveness of outsourcing as a form of organization of accounting.

  8. Tic disorders and the premonitory urge.

    Science.gov (United States)

    Steinberg, Tamar; Shmuel Baruch, Sharona; Harush, Adva; Dar, Ruvi; Woods, Doug; Piacentini, John; Apter, Alan

    2010-02-01

    The aims of this study were to examine a non-English (Hebrew) version of a scale that measures the premonitory urge in children suffering from tic disorder, as well as examine the correlations of the urge with demographic and clinical aspects of Tourette Syndrome. Forty children and adolescents, suffering from tics participated in this study. They were assessed with the Premonitory Urge for Tics Scale (PUTS); the Yale Global Tic Severity Scale (YGTSS); the Childhood Version of the Yale Brown Obsessive Compulsive Scale (CYBOCS); the ADHD Rating Scale IV (Conners) Scale; the Screen for Child Anxiety Related Emotional Disorders (SCARED); and the Child Depression Inventory (CDI). The mean PUTS score was 20.15 (SD = 5.89). For the entire sample the PUTS was found to be internally consistent at a = 0.79. Youths older than 10 years had higher consistency (a = 0.83) than youths younger than 10 (a = 0.69). Premonitory urge was not correlated with tic severity in the entire sample. In youths older than 10, as opposed to youths younger than 10, premonitory urge did correlate with obsessions, compulsions and depression, but not with anxiety or with ADHD. The premonitory urge can be measured reliably and the PUTS is a useful instrument for measuring this important phenomena. Premonitory urges seems to be related to obsessions, compulsions, and depression in older children and this may have implications for the developmental psychopatholgy of these symptoms.

  9. Urgências reprodutivas na cadela

    OpenAIRE

    Costa, Teresa Isabel Rodrigues da

    2010-01-01

    Dissertação de Mestrado Integrado em Medicina Veterinária As urgências reprodutivas ocorrem com frequência na prática clínica, estando o seu desfecho favorável associado a um diagnóstico e intervenção céleres. Na cadela, consideram-se urgências reprodutivas a distócia, a piómetra, o prolapso uterino, a torção uterina, a tetania puerperal, a metrite e a mastite. Esta dissertação tem por base a análise dos dados referentes à casuística de urgências reprodutivas em cadelas veri...

  10. URG11 Regulates Prostate Cancer Cell Proliferation, Migration, and Invasion

    Directory of Open Access Journals (Sweden)

    Bin Pan

    2018-01-01

    Full Text Available Upregulated gene 11 (URG11, a new gene upregulated by hepatitis B virus X protein, is involved in the development and progression of several tumors, including liver, stomach, lung, and colon cancers. However, the role of URG11 in prostate cancer remains yet to be elucidated. By determined expression in human prostate cancer tissues, URG11 was found significantly upregulated and positively correlated with the severity of prostate cancer, compared with that in benign prostatic hyperplasia tissues. Further, the mRNA and protein levels of URG11 were significantly upregulated in human prostate cancer cell lines (DU145, PC3, and LNCaP, compared with human prostate epithelial cell line (RWPE-1. Moreover, by the application of siRNA against URG11, the proliferation, migration, and invasion of prostate cancer cells were markedly inhibited. Genetic knockdown of URG11 also induced cell cycle arrest at G1/S phase, induced apoptosis, and decreased the expression level of β-catenin in prostate cancer cells. Overexpression of URG11 promoted the expression of β-catenin, the growth, the migration, and invasion ability of prostate cancer cells. Taken together, this study reveals that URG11 is critical for the proliferation, migration, and invasion in prostate cancer cells, providing the evidence of URG11 to be a novel potential therapeutic target of prostate cancer.

  11. Dalton Highway 9 to 11 Mile expedient resistivity permafrost investigation.

    Science.gov (United States)

    2014-01-01

    This project performed capacitive coupled resistivity surveys over a roadway reconstruction project in Interior Alaska, for the determination of permafrost extent. The : objective was to ascertain the ability of an expedient earth resistivity survey ...

  12. Upgrading Basements for Combined Nuclear Weapons Effects: Expedient Options

    Science.gov (United States)

    1976-05-01

    types of expedient ventilation systems are: 1. Construction of manually operated "flap-valve" (Kearny Air Pump) type systems, prefabricated from plywood...members installed side-by-side to close each opening, abutting the T-section web and perhaps sandbagged in place.) F. Materials/Labor Summary This

  13. Reproducible and expedient rice regeneration system using in vitro ...

    African Journals Online (AJOL)

    Inevitable prerequisite for expedient regeneration in rice is the selection of totipotent explant and developing an apposite combination of growth hormones. Here, we reported a reproducible regeneration protocol in which basal segments of the stem of the in vitro grown rice plants were used as ex-plant. Using the protocol ...

  14. Temporal relationship between premonitory urges and tics in Gilles de la Tourette syndrome.

    Science.gov (United States)

    Brandt, Valerie C; Beck, Christian; Sajin, Valeria; Baaske, Magdalena K; Bäumer, Tobias; Beste, Christian; Anders, Silke; Münchau, Alexander

    2016-04-01

    Premonitory urges are a cardinal feature in Tourette syndrome and are commonly viewed as the driving force of tics, building up before and subsiding after the execution of tics. Although the urge-tic interplay is one of the most preeminent features in Tourette syndrome, the temporal relationship between tics and urges has never been examined experimentally, mainly due to the lack of an appropriate assessment tool. We investigated the temporal relationship between urge intensity and tics in 17 Tourette patients and between urge intensity and eye blinks in 16 healthy controls in a free ticcing/blinking condition and a tic/blink suppression condition. For this purpose, an urge assessment tool was developed that allows real-time monitoring and quantification of urge intensity. Compared to free ticcing/blinking, urge intensity was higher during the suppression condition in both Tourette patients and healthy controls, while tics and blinks occurred less frequently. The data show that urge intensity increases prior to tics and decreases after tics in a time window of approximately ±10 sec. Tic suppression had a significant effect on the shape of the urge distribution around tics and led to a decrease in the size of the correlation between urge intensity and tics, indicating that tic suppression led to a de-coupling of tics and urges. In healthy controls, urges to blink were highly associated with eye blink execution, albeit in a narrower time frame (∼±5 sec). Blink suppression had a similar effect on the urge distribution associated with eye blinks as tic suppression had on the urge to tic in Tourette patients. These results corroborate the negative reinforcement model, which proposes that tics are associated with a relief in urges, thereby perpetuating ticcing behaviour. This study also documents similarities and differences between urges to act in healthy controls and urges to tic in Tourette syndrome. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. Investigating Habituation to Premonitory Urges in Behavior Therapy for Tic Disorders.

    Science.gov (United States)

    Houghton, David C; Capriotti, Matthew R; Scahill, Lawrence D; Wilhelm, Sabine; Peterson, Alan L; Walkup, John T; Piacentini, John; Woods, Douglas W

    2017-11-01

    Behavior therapy is effective for Persistent Tic Disorders (PTDs), but behavioral processes facilitating tic reduction are not well understood. One process, habituation, is thought to create tic reduction through decreases in premonitory urge severity. The current study tested whether premonitory urges decreased in youth with PTDs (N = 126) and adults with PTDs (N = 122) who participated in parallel randomized clinical trials comparing behavior therapy to psychoeducation and supportive therapy (PST). Trends in premonitory urges, tic severity, and treatment outcome were analyzed according to the predictions of a habituation model, whereby urge severity would be expected to decrease in those who responded to behavior therapy. Although adults who responded to behavior therapy showed a significant trend of declining premonitory urge severity across treatment, results failed to demonstrate that behavior therapy specifically caused changes in premonitory urge severity. In addition, reductions in premonitory urge severity in those who responded to behavior therapy were significant greater than those who did not respond to behavior therapy but no different than those who responded or did not respond to PST. Children with PTDs failed to show any significant changes in premonitory urges. Reductions in premonitory urge severity did not mediate the relationship between treatment and outcome in either adults or children. These results cast doubt on the notion that habituation is the therapeutic process underlying the effectiveness of behavior therapy, which has immediate implications for the psychoeducation and therapeutic rationale presented in clinical practice. Moreover, there may be important developmental changes in premonitory urges in PTDs, and alternative models of therapeutic change warrant investigation. Copyright © 2017. Published by Elsevier Ltd.

  16. XI Expedição Científica do Departamento de Biologia - Graciosa 2004.

    OpenAIRE

    Tavares, João; Furtado, Duarte

    2005-01-01

    XI Expedição Científica do Departamento de Biologia - Graciosa 2004. A Ilha Graciosa foi escolhida para a realização desta expedição científica por vários motivos e com diferentes objectivos, entre os quais salientamos: a sua situação geográfica; o seu reduzido tamanho; o grandioso e importante número de ilhéus que a rodeiam; os diversificados ecossistemas que a compõem. Neste projecto foi dada prioridade à zona costeira, que é sem dúvida uma verdadeira fronteira entre o mundo terrestre...

  17. Expedient Access to an N -phenylpyrrolidin-2-yl Heterocycle via a ...

    African Journals Online (AJOL)

    Expedient Access to an N -phenylpyrrolidin-2-yl Heterocycle via a Base-Induced Intramolecular aza -Michael Reaction. ... in good overall yield when employing a stoichiometric amount of base to facilitate the intramolecular aza-Michael reaction. Keywords: aza Michael, intramolecular, catalysed, piperidine, pyrrolidine, base ...

  18. Expediency of Study of the Scientists' Biographies in Physics Course

    Science.gov (United States)

    Korsun, Igor

    2017-01-01

    The aim of this article is a justification of the expediency of study of the scientists' biographies in physics course. Study of the biographic materials is one of the ways of motivation of learning and development of morality, humanity, internationalism. The selection criteria of biographic material have been allocated and method of study of the…

  19. A facile and expedient one-pot three-component reaction leading to ...

    Indian Academy of Sciences (India)

    Sci. Vol. 124, No. 5, September 2012, pp. 1007–1012. c Indian Academy of Sciences. A facile and expedient one-pot three-component reaction leading to multifunctionalized stabilized phosphorus ylides. ZAHRA HASSANI. ∗ and ZEINAB ESFANDIARPOUR. Department of New Materials, International Center for Science, ...

  20. Patterned changes in urge ratings with tic suppression in youth with chronic tic disorders.

    Science.gov (United States)

    Brabson, Laurel A; Brown, Jessica L; Capriotti, Matthew R; Ramanujam, Krishnapriya; Himle, Michael B; Nicotra, Cassandra M; Ostrander, Rick; Kelly, Laura M; Grados, Marco A; Walkup, John T; Perry-Parrish, Carisa; Reynolds, Elizabeth K; Hankinson, Jessica C; Specht, Matt W

    2016-03-01

    Premonitory urges are central to emerging behavioral models of chronic tic disorders (CTD). Urge reduction has been proposed as a behavioral explanation for tic maintenance and exacerbation as well as the efficacy of behavioral treatments. Prior investigations have produced inconsistent findings despite common methodologies. The current study evaluated the possibility that data aggregation obscures distinct and meaningful patterns of change in urge ratings when tics are freely expressed versus suppressed. Participants (n = 12) included children with moderate-to-marked tic severity and noticeable premonitory urges. Tic frequencies and urge ratings were obtained at 15 s and 10-s intervals, respectively, across an alternating sequence of 10-min tic freely and 40-min tic suppression conditions. Patterns were established using a two step approach. Five distinct patterns of urge rating change emerged, suggesting data aggregation may obscure meaningful patterns in the urge-tic relationship when tics are completed versus suppressed. Eligibility criteria may have unintentionally excluded younger affected children and included older participants with more severe tic disorders than commonly seen. Additional research with less stringent eligibility criteria and a larger sample size will help validate the results. The relationship between urges and tics is much more complex than previously theorized. Investigations that rely on global assessments of urge and tic severity and/or assume uniformity when aggregating participant data may obscure meaningful differences in the urge-tic relationship. Future investigations should examine the possibility that individual differences and/or developmental considerations modulate the functional urge-tic relationship. Copyright © 2015. Published by Elsevier Ltd.

  1. Relationships between Premonitory Urge and Anxiety in Youth with Chronic Tic Disorders.

    Science.gov (United States)

    Rozenman, Michelle; Johnson, Olivia E; Chang, Susanna W; Woods, Douglas W; Walkup, John T; Wilhelm, Sabine; Peterson, Alan; Scahill, Lawrence; Piacentini, John

    2015-07-01

    Tourette's Disorder and other chronic tic disorders are common neurodevelopmental conditions. One characteristic of tic disorders is the premonitory urge, an aversive or unpleasant sensory phenomenon that may precede tics. Initial examination of premonitory urge in pediatric tic disorders suggests that awareness and experience of sensations preceding tics may be related to anxiety and OCD. However, it may be possible that specific anxiety-related symptoms, such as anxious physiologic arousal, are particularly relevant to the experience of premonitory urge. The current study examines relationships between tic-related premonitory urge and anxiety-related symptom clusters in treatment-seeking youths with a primary diagnoses of Tourette's or other chronic tic disorder. The sample consisted of 124 youth, ages 9 to 17, who participated in the multi-site Comprehensive Behavioral Intervention for Tics randomized controlled trial (CBIT; Piacentini et al., 2010). Specific anxiety-related subtypes, including generalized worry, separation, social, and panic/somatic symptoms, as well as severity of obsessions and compulsions, were assessed as potential correlates of premonitory urge. Findings indicated that age, global tic-related impairment, and specific panic/somatic symptoms accounted for a substantial proportion of variance in youth report of premonitory urge. These findings provide information about the characteristics of premonitory urge in pediatric tic disorders, and have implications for the treatment of pediatric tic syndromes.

  2. Negative Reinforcement and Premonitory Urges in Youth With Tourette Syndrome: An Experimental Evaluation.

    Science.gov (United States)

    Capriotti, Matthew R; Brandt, Bryan C; Turkel, Jennifer E; Lee, Han-Joo; Woods, Douglas W

    2014-03-01

    Tourette syndrome (TS) is marked by the chronic presence of motor and vocal tics that are usually accompanied by aversive sensory experiences called "premonitory urges." Phenomenological accounts suggest that these urges occur before tics and diminish following their occurrence. This has led some to suggest that tics are negatively reinforced by removal of premonitory urges. This hypothesis has proven difficult to test experimentally, however, due in part to challenges in measuring premonitory urge strength. We tested predictions of the negative reinforcement conceptualization of premonitory urges using novel experimental tactics within the context of the "tic detector" paradigm. We compared tic rates and ratings of premonitory urge strength exhibited by youth with TS or chronic tic disorder under free-to-tic baseline (BL), reinforced tic suppression (RTS), and reinforced tic suppression with escape (RTS + E) conditions. Results were consistent with previous research and hypotheses of the present study. Participants rated the strength of their premonitory urges as higher during RTS conditions than during BL conditions. Within RTS + E conditions, tic rates were higher during escape portions when the contingency supporting tic suppression was inactive than during components where the contingency was active, and ratings of urge strength were higher at the onset of break periods than at the offset. All participants engaged in some level of escape from reinforced suppression during the course of the experiment. Results of this study support the notion that tics may be negatively reinforced by removal of aversive premonitory urges. Future directions for basic and clinical research are discussed. © The Author(s) 2014.

  3. Computer Technology for Expediency Consideration of Transformer Switching-Off for Capital Repair

    Directory of Open Access Journals (Sweden)

    E. M. Farkhadzade

    2011-01-01

    Full Text Available The paper considers computer technologies for expediency consideration of worn-out transformer recovery in power systems. Methods for list preparation of transformers to be selected for capital repair, estimation of repair quality, control over execution of contractual obligations are presented in the paper.

  4. Brain activities associated with gaming urge of online gaming addiction.

    Science.gov (United States)

    Ko, Chih-Hung; Liu, Gin-Chung; Hsiao, Sigmund; Yen, Ju-Yu; Yang, Ming-Jen; Lin, Wei-Chen; Yen, Cheng-Fang; Chen, Cheng-Sheng

    2009-04-01

    The aim of this study was to identify the neural substrates of online gaming addiction through evaluation of the brain areas associated with the cue-induced gaming urge. Ten participants with online gaming addiction and 10 control subjects without online gaming addiction were tested. They were presented with gaming pictures and the paired mosaic pictures while undergoing functional magnetic resonance imaging (fMRI) scanning. The contrast in blood-oxygen-level dependent (BOLD) signals when viewing gaming pictures and when viewing mosaic pictures was calculated with the SPM2 software to evaluate the brain activations. Right orbitofrontal cortex, right nucleus accumbens, bilateral anterior cingulate and medial frontal cortex, right dorsolateral prefrontal cortex, and right caudate nucleus were activated in the addicted group in contrast to the control group. The activation of the region-of-interest (ROI) defined by the above brain areas was positively correlated with self-reported gaming urge and recalling of gaming experience provoked by the WOW pictures. The results demonstrate that the neural substrate of cue-induced gaming urge/craving in online gaming addiction is similar to that of the cue-induced craving in substance dependence. The above-mentioned brain regions have been reported to contribute to the craving in substance dependence, and here we show that the same areas were involved in online gaming urge/craving. Thus, the results suggest that the gaming urge/craving in online gaming addiction and craving in substance dependence might share the same neurobiological mechanism.

  5. Premonitory urges and tics in Tourette syndrome: computational mechanisms and neural correlates.

    Science.gov (United States)

    Conceição, Vasco A; Dias, Ângelo; Farinha, Ana C; Maia, Tiago V

    2017-10-01

    Tourette syndrome is characterized by open motor behaviors - tics - but another crucial aspect of the disorder is the presence of premonitory urges: uncomfortable sensations that typically precede tics and are temporarily alleviated by tics. We review the evidence implicating the somatosensory cortices and the insula in premonitory urges and the motor cortico-basal ganglia-thalamo-cortical loop in tics. We consider how these regions interact during tic execution, suggesting that the insula plays an important role as a nexus linking the sensory and emotional character of premonitory urges with their translation into tics. We also consider how these regions interact during tic learning, integrating the neural evidence with a computational perspective on how premonitory-urge alleviation reinforces tics. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Role of the right dorsal anterior insula in the urge to tic in Tourette syndrome.

    Science.gov (United States)

    Tinaz, Sule; Malone, Patrick; Hallett, Mark; Horovitz, Silvina G

    2015-08-01

    The mid-posterior part of the insula is involved in processing bodily sensations and urges and is activated during tic generation in Tourette syndrome. The dorsal anterior part of the insula, however, integrates sensory and emotional information with cognitive valuation and is implicated in interoception. The right dorsal anterior insula also participates in urge suppression in healthy subjects. This study examined the role of the right dorsal anterior insula in the urge to tic in Tourette syndrome. Resting-state functional magnetic resonance imaging was performed in 13 adult Tourette patients and 13 matched controls. The role of the right dorsal anterior insula within the urge-tic network was investigated using graph theory-based neural network analysis. The functional connectivity of the right dorsal anterior insula was also correlated with urge and tic severity. Even though the patients did not exhibit any overt tics, the right dorsal anterior insula demonstrated higher connectivity, especially with the frontostriatal nodes of the urge-tic network in patients compared with controls. The functional connectivity between the right dorsal anterior insula and bilateral supplementary motor area also correlated positively with urge severity in patients. These results suggest that the right dorsal anterior insula is part of the urge-tic network and could influence the urge- and tic-related cortico-striato-thalamic regions even during rest in Tourette syndrome. It might be responsible for heightened awareness of bodily sensations generating premonitory urges in Tourette syndrome. © 2015 International Parkinson and Movement Disorder Society.

  7. The premonitory urge to tic: measurement, characteristics, and correlates in older adolescents and adults.

    Science.gov (United States)

    Reese, Hannah E; Scahill, Lawrence; Peterson, Alan L; Crowe, Katherine; Woods, Douglas W; Piacentini, John; Walkup, John T; Wilhelm, Sabine

    2014-03-01

    In addition to motor and/or vocal tics, many individuals with Tourette syndrome (TS) or chronic tic disorder (CTD) report frequent, uncomfortable sensory phenomena that immediately precede the tics. To date, examination of these premonitory sensations or urges has been limited by inconsistent assessment tools. In this paper, we examine the psychometric properties of a nine-item self-report measure, the Premonitory Urge to Tic Scale (PUTS) and examine the characteristics and correlates of the premonitory urge to tic in a clinical sample of 122 older adolescents and adults with TS or CTD. The PUTS demonstrated adequate internal consistency, temporal stability, and concurrent validity. Premonitory urges were endorsed by the majority of individuals. Most individuals reported some relief from the urges after completing a tic and being able to stop their tics even if only temporarily. Degree of premonitory urges was not significantly correlated with age, and we did not observe any gender differences. Degree of premonitory urges was significantly correlated with estimated IQ and tic severity, but not severity of comorbid obsessive-compulsive disorder or attention-deficit hyperactivity disorder. Also, it was not related to concomitant medication status. These findings represent another step forward in our understanding of the premonitory sensations associated with TS and CTD. © 2013.

  8. Positive and negative affect as predictors of urge to smoke: temporal factors and mediational pathways.

    Science.gov (United States)

    Leventhal, Adam M; Greenberg, Jodie B; Trujillo, Michael A; Ameringer, Katherine J; Lisha, Nadra E; Pang, Raina D; Monterosso, John

    2013-03-01

    Elucidating interrelations between prior affective experience, current affective state, and acute urge to smoke could inform affective models of addiction motivation and smoking cessation treatment development. This study tested the hypothesis that prior levels of positive (PA) and negative (NA) affect predict current smoking urge via a mediational pathway involving current state affect. We also explored if tobacco deprivation moderated affect-urge relations and compared the effects of PA and NA on smoking urge to one another. At a baseline session, smokers reported affect experienced over the preceding few weeks. At a subsequent experimental session, participants were randomly assigned to 12-hr tobacco deprived (n = 51) or nondeprived (n = 69) conditions and reported state affect and current urge. Results revealed a mediational pathway whereby prior NA reported at baseline predicted state NA at the experimental session, which in turn predicted current urge. This mediational pathway was found primarily for an urge subtype indicative of urgent need to smoke and desire to smoke for NA relief, was stronger in the deprived (vs. nondeprived) condition, and remained significant after controlling for PA. Prior PA and current state PA were inversely associated with current urge; however, these associations were eliminated after controlling for NA. These results cohere with negative reinforcement models of addiction and with prior research and suggest that: (a) NA plays a stronger role in smoking motivation than PA; (b) state affect is an important mechanism linking prior affective experience to current urge; and (c) affect management interventions may attenuate smoking urge in individuals with a history of affective disturbance. (PsycINFO Database Record (c) 2013 APA, all rights reserved).

  9. Gender differences in temporal relationships between gambling urge and cognitions in treatment-seeking adults.

    Science.gov (United States)

    Dunsmuir, Phoebe; Smith, David; Fairweather-Schmidt, A Kate; Riley, Ben; Battersby, Malcolm

    2018-04-01

    Many gambling-specific CBT programs seek to target either gambling-related urge or cognitions or both. However, little is known of the influence of one symptom type on another across time and whether these differ for men and women help-seeking problem gamblers. The aim of this study was threefold: to determine presence of measurement invariance for urge and cognition measures over time; to investigate the effect of baseline urge on end-of-treatment gambling-related cognitions - and the reciprocal relationship; and, identify whether these pathways differ across gender. Self-reported gambling urge (GUS), and gambling-related cognitions (GRCS) data from treatment-seeking problem gamblers prior to and post treatment (N = 223; 62% men) were analyzed with cross-lagged panel models, moderated by gender. Conceptualization of urge and cognitions were found to be temporally stable. There was no significant association between baseline GUS scores and post-treatment GRCS scores, nor the reverse relationship. Putatively, this infers that coexisting urge and gambling-related cognition components of problem gambling operate independently over time. Analyses revealed gambling urge had a significantly stronger tracking correlation across time for men than women when adjusting for cognition paths. This investigation provides early evidence for tailoring CBT in response to sub-population gambling-related characteristics, demonstrated across men and women. Copyright © 2018 Elsevier B.V. All rights reserved.

  10. Distinct coping strategies differentially predict urge levels and lapses in a smoking cessation attempt.

    Science.gov (United States)

    Brodbeck, Jeannette; Bachmann, Monica S; Znoj, Hansjörg

    2013-06-01

    This study analysed mechanisms through which stress-coping and temptation-coping strategies were associated with lapses. Furthermore, we explored whether distinct coping strategies differentially predicted reduced lapse risk, lower urge levels, or a weaker association between urge levels and lapses during the first week of an unassisted smoking cessation attempt. Participants were recruited via the internet and mass media in Switzerland. Ecological momentary assessment (EMA) with mobile devices was used to assess urge levels and lapses. Online questionnaires were used to measure smoking behaviours and coping variables at baseline, as well as smoking behaviour at the three-month follow-up. The sample consisted of 243 individuals, aged 20 to 40, who reported 4199 observations. Findings of multilevel regression analyses show that coping was mainly associated with a reduced lapse risk and not with lower urge levels or a weaker association between urge levels and lapses. 'Calming down' and 'commitment to change' predicted a lower lapse risk and also a weaker relation between urge levels and lapses. 'Stimulus control' predicted a lower lapse risk and lower urge levels. Conversely, 'task-orientation' and 'risk assessment' were related to higher lapse risk and 'risk assessment' also to higher urge levels. Disengagement coping i.e. 'eating or shopping', 'distraction', and 'mobilising social support' did not affect lapse risk. Promising coping strategies during the initial stage of smoking cessation attempt are targeted directly at reducing the lapse risk and are characterised by engagement with the stressor or one's reactions towards the stressor and a focus on positive consequences instead of health risks. Copyright © 2013 Elsevier Ltd. All rights reserved.

  11. Classifying smoking urges via machine learning.

    Science.gov (United States)

    Dumortier, Antoine; Beckjord, Ellen; Shiffman, Saul; Sejdić, Ervin

    2016-12-01

    Smoking is the largest preventable cause of death and diseases in the developed world, and advances in modern electronics and machine learning can help us deliver real-time intervention to smokers in novel ways. In this paper, we examine different machine learning approaches to use situational features associated with having or not having urges to smoke during a quit attempt in order to accurately classify high-urge states. To test our machine learning approaches, specifically, Bayes, discriminant analysis and decision tree learning methods, we used a dataset collected from over 300 participants who had initiated a quit attempt. The three classification approaches are evaluated observing sensitivity, specificity, accuracy and precision. The outcome of the analysis showed that algorithms based on feature selection make it possible to obtain high classification rates with only a few features selected from the entire dataset. The classification tree method outperformed the naive Bayes and discriminant analysis methods, with an accuracy of the classifications up to 86%. These numbers suggest that machine learning may be a suitable approach to deal with smoking cessation matters, and to predict smoking urges, outlining a potential use for mobile health applications. In conclusion, machine learning classifiers can help identify smoking situations, and the search for the best features and classifier parameters significantly improves the algorithms' performance. In addition, this study also supports the usefulness of new technologies in improving the effect of smoking cessation interventions, the management of time and patients by therapists, and thus the optimization of available health care resources. Future studies should focus on providing more adaptive and personalized support to people who really need it, in a minimum amount of time by developing novel expert systems capable of delivering real-time interventions. Copyright © 2016 Elsevier Ireland Ltd. All rights

  12. New insights on the functional role of URG7 in the cellular response to ER stress.

    Science.gov (United States)

    Armentano, Maria Francesca; Caterino, Marianna; Miglionico, Rocchina; Ostuni, Angela; Pace, Maria Carmela; Cozzolino, Flora; Monti, Maria; Milella, Luigi; Carmosino, Monica; Pucci, Piero; Bisaccia, Faustino

    2018-04-28

    Up-regulated Gene clone 7 (URG7) is an ER resident protein, whose expression is up-regulated in the presence of hepatitis B virus X antigen (HBxAg) during HBV infection. In virus-infected hepatocytes, URG7 shows an anti-apoptotic activity due to the PI3K/AKT signalling activation, does not seem to have tumorigenic properties, but it appears to promote the development and progression of fibrosis. However, the molecular mechanisms underlying URG7 activity remain largely unknown. To shed light on URG7 activity, we first analysed its interactome in HepG2 transfected cells: this analysis suggests that URG7 could have a role in affecting protein synthesis, folding and promoting proteins degradation. Moreover, keeping into account its subcellular localisation in the ER and that several viral infections give rise to ER stress, a panel of experiments was performed to evaluate a putative role of URG7 in ER stress. Our main results demonstrate that in ER-stressed cells URG7 is able to modulate the expression of Unfolded Protein Response (UPR) markers towards survival outcomes, up-regulating GRP78 protein and down-regulating the pro-apoptotic protein CHOP. Furthermore, URG7 reduces the ER stress by decreasing the amount of unfolded proteins, by increasing both the total protein ubiquitination and the AKT activation and reducing Caspase 3 activation. All together these data suggest that URG7 plays a pivotal role as a reliever of ER stress-induced apoptosis. This is the first characterisation of URG7 activity under ER stress conditions. The results presented here will help to hypothesise new strategies to counteract the antiapoptotic activity of URG7 in the context of the viral infection. © 2018 Société Française des Microscopies and Société de Biologie Cellulaire de France. Published by John Wiley & Sons Ltd.

  13. Apresentação da XI Expedição Científica do Departamento de Biologia : GRACIOSA 2004.

    OpenAIRE

    Tavares, João

    2005-01-01

    XI Expedição Científica do Departamento de Biologia - Graciosa 2004. A Ilha Graciosa foi escolhida para a realização desta expedição científica por vários motivos e com diferentes objectivos, entre os quais salientamos: a sua situação geográfica; o seu reduzido tamanho; o grandioso e importante número de ilhéus que a rodeiam; os diversificados ecossistemas que a compõem. Neste projecto foi dada prioridade à zona costeira, que é sem dúvida uma verdadeira fronteira entre o mundo terrestre...

  14. URG11 mediates hypoxia-induced epithelial-to-mesenchymal transition by modulation of E-cadherin and β-catenin

    International Nuclear Information System (INIS)

    Du, Rui; Huang, Chen; Bi, Qian; Zhai, Ying; Xia, Lin; Liu, Jie; Sun, Shiren; Fan, Daiming

    2010-01-01

    Upregulated gene 11 (URG11), recently identified as a new HBx-upregulated gene that may activate β-catenin and Wnt signaling, was found to be upregulated in a human tubule cell line under low oxygen. Here, we investigated the potential role of URG11 in hypoxia-induced renal tubular epithelial-to-mesenchymal (EMT). Overexpression of URG11 in a human proximal tubule cell line (HK2) promoted a mesenchymal phenotype accompanied by reduced expression of the epithelial marker E-cadherin and increased expression of the mesenchymal markers vimentin and α-SMA, while URG11 knockdown by siRNA effectively reversed hypoxia-induced EMT. URG11 promoted the expression of β-catenin and increased its nuclear accumulation under normoxic conditions through transactivation of the β-catenin promoter. This in turn upregulated β-catenin/T-cell factor (TCF) and its downstream effector genes, vimentin, and α-SMA. In vivo, strong expression of URG11 was observed in the tubular epithelia of 5/6-nephrectomized rats, and a Western blot analysis demonstrated a close correlation between HIF-1α and URG11 protein levels. Altogether, our results indicate that URG11 mediates hypoxia-induced EMT through the suppression of E-cadherin and the activation of the β-catenin/TCF pathway.

  15. A expedição portuguesa ao Brasil em 1501-1502 e Amerigo Vespucci

    Directory of Open Access Journals (Sweden)

    Thomaz Oscar Marcondes de Souza

    1960-07-01

    Full Text Available O único cronista português que dá notícia do envio, pelo rei D. Manuel, de uma expedição exploradora ao litoral brasileiro em 1501 é Antônio Gaivão, na sua obra publicada em Lisboa em 1563 sob o título: Tratado dos Descobrimentos.

  16. Exposure to electronic nicotine delivery systems (ENDS) visual imagery increases smoking urge and desire.

    Science.gov (United States)

    King, Andrea C; Smith, Lia J; Fridberg, Daniel J; Matthews, Alicia K; McNamara, Patrick J; Cao, Dingcai

    2016-02-01

    Use and awareness of electronic nicotine delivery systems (ENDS; also known as electronic cigarettes or e-cigarettes) has increased rapidly in recent years, particularly among young adults. As use of ENDS resembles traditional smoking in both hand-to-mouth movements and inhalation and exhalation behaviors, we determined whether exposure to e-cigarette use via video exposure would act as a cue to elicit urge and desire for a combustible cigarette. Young adult smokers (mean age of 26.3 ± 4.1 years) were randomized to view a brief video montage of advertisements depicting either e-cigarette vaping (n = 38) or bottled water drinking (n = 40). Pre- and postcue exposure assessments were conducted in a controlled laboratory setting without other smoking or vaping cues present or behaviors allowed. Primary outcomes included change from pre-exposure baseline in smoking urge (Brief Questionnaire of Smoking Urges) and desire for a combustible and e-cigarette (visual analogue scales). Results showed that relative to exposure to the bottled water video, exposure to the ENDS video significantly increased smoking urge (p e-cigarette (p < .001). These findings provide preliminary evidence that passive exposure to video imagery of ENDS use may generalize as a condition cue and evoke urges for a combustible cigarette in young adult smokers. It remains to be determined whether such increases in urge and desire correspond to increases in actual smoking behavior. (c) 2016 APA, all rights reserved).

  17. Trait Mindfulness, Problem-Gambling Severity, Altered State of Awareness and Urge to Gamble in Poker-Machine Gamblers.

    Science.gov (United States)

    McKeith, Charles F A; Rock, Adam J; Clark, Gavin I

    2017-06-01

    In Australia, poker-machine gamblers represent a disproportionate number of problem gamblers. To cultivate a greater understanding of the psychological mechanisms involved in poker-machine gambling, a repeated measures cue-reactivity protocol was administered. A community sample of 38 poker-machine gamblers was assessed for problem-gambling severity and trait mindfulness. Participants were also assessed regarding altered state of awareness (ASA) and urge to gamble at baseline, following a neutral cue, and following a gambling cue. Results indicated that: (a) urge to gamble significantly increased from neutral cue to gambling cue, while controlling for baseline urge; (b) cue-reactive ASA did not significantly mediate the relationship between problem-gambling severity and cue-reactive urge (from neutral cue to gambling cue); (c) trait mindfulness was significantly negatively associated with both problem-gambling severity and cue-reactive urge (i.e., from neutral cue to gambling cue, while controlling for baseline urge); and (d) trait mindfulness did not significantly moderate the effect of problem-gambling severity on cue-reactive urge (from neutral cue to gambling cue). This is the first study to demonstrate a negative association between trait mindfulness and cue-reactive urge to gamble in a population of poker-machine gamblers. Thus, this association merits further evaluation both in relation to poker-machine gambling and other gambling modalities.

  18. Relationships between Premonitory Urge and Anxiety in Youth with Chronic Tic Disorders

    OpenAIRE

    Rozenman, Michelle; Johnson, Olivia E.; Chang, Susanna W.; Woods, Douglas W.; Walkup, John T.; Wilhelm, Sabine; Peterson, Alan; Scahill, Lawrence; Piacentini, John

    2014-01-01

    Tourette's Disorder and other chronic tic disorders are common neurodevelopmental conditions. One characteristic of tic disorders is the premonitory urge, an aversive or unpleasant sensory phenomenon that may precede tics. Initial examination of premonitory urge in pediatric tic disorders suggests that awareness and experience of sensations preceding tics may be related to anxiety and OCD. However, it may be possible that specific anxiety-related symptoms, such as anxious physiologic arousal,...

  19. National centers urged to team up, compete

    CERN Multimedia

    König, R

    2001-01-01

    A new report from Germany's scientific evaluatory body states that the national research centers are too insular. It urges the government to foster cooperation and competition between themselves and outside labs. It suggests using a USA style funding model with research programs that cut across many institutions rather than block grants to individual facilities (1 page).

  20. Increased Urge to Gamble Following Near-Miss Outcomes May Drive Purchasing Behaviour in Scratch Card Gambling.

    Science.gov (United States)

    Stange, Madison; Graydon, Candice; Dixon, Mike J

    2017-09-01

    Previous research into scratch card gambling has highlighted the effects of these games on players' arousal and affective states. Specifically, near-miss outcomes in scratch cards (uncovering 2 of 3 needed jackpot symbols) have been associated with high levels of physiological and subjective arousal and negative emotional evaluations, including increased frustration. We sought to extend this research by examining whether near-misses prompted increases in gambling urge, and the subsequent purchasing of additional scratch cards. Participants played two scratch cards with varying outcomes with half of the sample experiencing a near-miss for the jackpot prize, and the other half experiencing a regular loss. Players rated their urge to continue gambling after each game outcome, and following the initial playing phase, were then able to use their winnings to purchase additional cards. Our results indicated that near-misses increased the urge to gamble significantly more than regular losses, and urge to gamble in the near-miss group was significantly correlated with purchasing at least one additional card. Although some players in the loss group purchased another card, there was no correlation between urge to gamble and purchasing in this group. Additionally, participants in the near-miss group who purchased additional cards reported higher levels of urge than those who did not purchase more cards. This was not true for the loss group: participants who experienced solely losing outcomes reported similar levels of urge regardless of whether or not they purchased more scratch cards. Despite near-misses' objective status as monetary losses, the increased urge that follows near-miss outcomes may translate into further scratch card gambling for a subset of individuals .

  1. Examining Cognitive Processes and Drinking Urge in PTSD

    Science.gov (United States)

    Bachrach, Rachel L.; Wardell, Jeffrey D.; Coffey, Scott F.

    2018-01-01

    Despite their centrality to learning theories, strikingly little attention has been paid to the role of cognitions in efforts to understand associations between posttraumatic stress disorder (PTSD) and alcohol drinking. In the present study, we sought to examine information processing pathways for trauma and alcohol information, and the effects of posttraumatic stress and trauma cue exposure on these pathways. Participants were college students (N = 232; 49% female; Mage = 19.56,SD = 1.44) categorized into three diagnostic groups based on current PTSD status determined by structured clinical interview. These students then were exposed to a personalized trauma or neutral cue script, followed by a Stroop task modified to include trauma, alcohol, and contrast words. Indices of mood and urge to drink alcohol were administered throughout the task. Findings revealed that those with PTSD who were exposed to the personalized trauma cue showed a general response slowing across all stimuli types on the Stroop task. Intriguingly, this slowing effect was significantly associated with urge to drink alcohol for only those PTSD participants who were exposed to the trauma cues. In contrast, we did not find support for the hypothesis that trauma cues would lead to attention bias to trauma and alcohol specific Stroop stimuli among participants with PTSD, nor did slower RT for specific word types predict unique variance in urge to drink alcohol. Findings suggest that individual (PTSD) and environmental (cue) circumstances may work conjointly to precipitate changes in cognitive processing - changes that may have implications for drinking motivation. Given the importance of cognition in the etiology of both PTSD and drinking, this is a mechanism that warrants further investigation. PMID:28073047

  2. Researchers urge climate-resilience support for South African maize ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2016-04-20

    Apr 20, 2016 ... Researchers urge climate-resilience support for South African maize farmers ... They found that climate change is likely to hurt livelihoods and food security ... In Burkina Faso, local cultivation and livestock practices are losing ...

  3. Expediency of Study of the Scientists' Biographies in Physics Course

    Directory of Open Access Journals (Sweden)

    Igor Korsun

    2017-04-01

    Full Text Available The aim of this article is a justification of the expediency of study of the scientists' biographies in physics course. Study of the biographic materials is one of the ways of motivation of learning and development of morality, humanity, internationalism. The selection criteria of biographic material have been allocated and method of study of the scientists' biographies has been described. Biographical data, scientific achievements and character traits are the components of “scientist's image”. Results proved that the use of the biographic materials raises the level of emotional component of learners' cognitive activity in physics teaching. Method of study of the scientists' biographies can be used in teaching of other school subjects.

  4. Brussels questions power grid sell-off

    Index Scriptorium Estoniae

    2007-01-01

    Euroopa Komisjon palus Leedu majandusministeeriumilt selgitust Lääne-Leedu elektrivõrgufirma Vakaru Skirstomieji Tinklai erastamise kohta. Peaminister Kirkilas kaitseb otsust ühendada kolm energiakompaniid üheks

  5. Hepatitis Bx Antigen Stimulates Expression of a Novel Cellular Gene, URG4, that Promotes Hepatocellular Growth and Survival

    Directory of Open Access Journals (Sweden)

    N. Lale Satiroglu Tufan

    2002-01-01

    Full Text Available Hepatitis B virus encoded X antigen (HBxAg may contribute to the development of hepatocellular carcinoma (HCC by up-or downregulating the expression of cellular genes that promote cell growth and survival. To test this hypothesis, HBxAg-positive and-negative HepG2 cells were constructed, and the patterns of cellular gene expression compared by polymerase chain reaction select cDNA subtraction. The full-length clone of one of these upregulated genes (URG, URG4, encoded a protein of about 104 kDa. URG4 was strongly expressed in hepatitis 13-infected liver and in HCC cells, where it costained with HBxAg, and was weakly expressed in uninfected liver, suggesting URG4 was an effector of HBxAg in vivo. Overexpression of URG4 in HepG2 cells promoted hepatocellular growth and survival in tissue culture and in soft agar, and accelerated tumor development in nude mice. Hence, URG4 may be a natural effector of HBxAg that contributes importantly to multistep hepatocarcinogenesis.

  6. Expedient pyrrolizidine synthesis by propargylsilane addition to N-acyliminium ions followed by gold-catalyzed α-allenyl amide cyclization

    NARCIS (Netherlands)

    Breman, A.C.; Dijkink, J.; van Maarseveen, J.H.; Kinderman, S.S.; Hiemstra, H.

    2009-01-01

    A reaction sequence, involving the addition of (substituted) propargylsilanes to lactate-derived N-acyliminium ions followed by gold-catalyzed cyclization of the resulting alpha-allenyl amide, is applied in expedient syntheses of pyrrolizidine alkaloids heliotridine and ent-retronecine in five steps

  7. Expedient Syntheses of Neutral and Cationic Au(I)–NHC Complexes

    KAUST Repository

    Veenboer, Richard M. P.

    2017-09-08

    The synthesis and isolation of gold(I) precatalysts often requires the generation of several isolable intermediates as well as numerous purification steps. New protocols for the expedient synthesis of neutral [Au(OH)(NHC)] and [Au(CH2COCH3)(NHC)] species from [AuCl(NHC)] or [AuCl(DMS)] precursors bearing a variety of N-heterocyclic carbene (NHC) ligands are presented. These methods can be employed in a telescoping manner for the synthesis of catalytically relevant [Au(NTf2)(NHC)] and [Au(NHC)(NCCH3)][BF4] complexes. These attractive methods are straightforward and practical leading to various complexes in high isolated yields and purity.

  8. Expedient Syntheses of Neutral and Cationic Au(I)–NHC Complexes

    KAUST Repository

    Veenboer, Richard M. P.; Gasperini, Danila; Nahra, Fady; Cordes, David B.; Slawin, Alexandra M. Z.; Cazin, Catherine S. J.; Nolan, Steven P.

    2017-01-01

    The synthesis and isolation of gold(I) precatalysts often requires the generation of several isolable intermediates as well as numerous purification steps. New protocols for the expedient synthesis of neutral [Au(OH)(NHC)] and [Au(CH2COCH3)(NHC)] species from [AuCl(NHC)] or [AuCl(DMS)] precursors bearing a variety of N-heterocyclic carbene (NHC) ligands are presented. These methods can be employed in a telescoping manner for the synthesis of catalytically relevant [Au(NTf2)(NHC)] and [Au(NHC)(NCCH3)][BF4] complexes. These attractive methods are straightforward and practical leading to various complexes in high isolated yields and purity.

  9. Premonitory urges for tics in adult patients with Tourette syndrome.

    Science.gov (United States)

    Crossley, Eleanor; Seri, Stefano; Stern, Jeremy S; Robertson, Mary M; Cavanna, Andrea E

    2014-01-01

    Patients with Tourette syndrome (TS) often report characteristic sensory experiences, also called premonitory urges (PUs), which precede tic expression and have high diagnostic relevance. This study investigated the usefulness of a scale developed and validated in children and adolescents-the Premonitory Urge for Tics Scale (PUTS, Woods et al., 2005 [13])-for the assessment of PUs in adult patients with TS. Standard statistical methods were applied to test the psychometric properties of the PUTS in 102 adult TS outpatients recruited from two specialist clinics in the United Kingdom. The PUTS showed good acceptability and endorsement rates, with evenly distributed scores and low floor and ceiling effects. Item-total correlations were moderate to strong; PUTS total scores were significantly correlated with quantitative measures of TS severity. The PUTS showed excellent internal consistency reliability (Cronbach's alpha=0.85) and Spearman's correlations demonstrated satisfactory convergent and discriminant validity. Although originally devised to assess urges to tic in young patients with TS, the PUTS demonstrated good psychometric properties in a large sample of adults recruited at specialist TS clinics. This instrument is therefore recommended for use across the life span as a valid and reliable self-report measure of sensory experiences accompanying tic expression. Copyright © 2013 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

  10. Positive smoking outcome expectancies mediate the association between negative affect and smoking urge among women during a quit attempt.

    Science.gov (United States)

    Cano, Miguel Ángel; Lam, Cho Y; Chen, Minxing; Adams, Claire E; Correa-Fernández, Virmarie; Stewart, Diana W; McClure, Jennifer B; Cinciripini, Paul M; Wetter, David W

    2014-08-01

    Ecological momentary assessment was used to examine associations between negative affect, positive smoking outcome expectancies, and smoking urge during the first 7 days of a smoking quit attempt. Participants were 302 female smokers who enrolled in an individually tailored smoking cessation treatment study. Multilevel mediation analysis was used to examine the temporal relationship among the following: (a) the effects of negative affect and positive smoking outcome expectancies at 1 assessment point (e.g., time j) on smoking urge at the subsequent time point (e.g., time j + 1) in Model 1; and, (b) the effects of negative affect and smoking urge at time j on positive smoking outcome expectancies at time j + 1 in Model 2. The results from Model 1 showed a statistically significant effect of negative affect at time j on smoking urge at time j + 1, and this effect was mediated by positive smoking outcome expectancies at time j, both within- and between-participants. In Model 2, the within-participant indirect effect of negative affect at time j on positive smoking outcome expectancies at time j + 1 through smoking urge at time j was nonsignificant. However, a statistically significant indirect between-participants effect was found in Model 2. The findings support the hypothesis that urge and positive smoking outcome expectancies increase as a function of negative affect, and suggest a stronger effect of expectancies on urge as opposed to the effect of urge on expectancies.

  11. Pakistan strong industrial base urged for economic progress

    CERN Multimedia

    2001-01-01

    A conference organized by Pakistan Nuclear Society urged that Pakistan should develop a strong industrial base and capability to export equipment for economic progress. The chairmen of PAEC pointed out that Pakistan is already showing remarkable progress in export of science-related equipment to CERN. He also asked scientists to wage a war against Pakistans inability to acquire indigenous technology (1 page).

  12. Malalties de transmissió sexual a urgències pediàtriques

    OpenAIRE

    Díaz Sabogal, Diana; Curcoy Barcenilla, Ana Isabel; Trenchs Sainz de la Maza, Victoria; Giménez Roca, Clara; Luaces Cubells, Carles

    2014-01-01

    Determinar les característiques dels pacients diag- nosticats de malalties de transmissió sexual (MTS) a urgèn- cies i establir la freqüència en què són degudes a abús sexual. Mètode. Estudi retrospectiu fet entre el gener del 2007 i el desembre del 2011. S'inclouen els pacients menors de 18 anys diagnosticats a urgències d'MTS -infecció per Neisse- ria gonorrhoeae, Chlamydia trachomatis, Treponema palli- dum, , virus d'immunodeficiència humana (VIH), virus del pa- pil loma humà (VPH) i virus...

  13. The impact of harmfulness information on citric acid induced cough and urge-to-cough.

    Science.gov (United States)

    Janssens, Thomas; Brepoels, Sarah; Dupont, Lieven; Van den Bergh, Omer

    2015-04-01

    The cough reflex is an automatic protective reflex, which can be modulated by conscious effort or other forms of top-down control. In this experiment, we investigated whether information about harmfulness of a cough-inducing substance would augment cough reflex sensitivity and associated urge-to-cough. Healthy participants (N = 39) were randomized to receive information that they were to inhale a harmless substance (natural citric acid), or a potentially harmful substance (a potent agro-chemical acid). Using dosimeter-controlled inhalations, the dose of citric acid eliciting at least three coughs (C3) was determined. Next, participants received 4 blocks of randomized presentations of citric acid at the C3 dose, a sub-threshold dose of citric acid and saline control. C3 was reached for 27/39 participants, and C3 thresholds were not influenced by harmfulness information. During repeated citric acid presentations, framing the cough-inducing substance as a potentially harmful chemical resulted in a greater urge-to-cough compared to information framing it as natural citric acid (p < .01). The experimental manipulation did not influence cough frequencies. Our findings show that harmfulness information influences urge-to-cough, corroborating the role of cortical mechanisms in modulating the urge-to-cough and suggesting that cognitive manipulations may contribute to cough treatment. Copyright © 2015 Elsevier Ltd. All rights reserved.

  14. A Prototypical First-Generation Electronic Cigarette Does Not Reduce Reports of Tobacco Urges or Withdrawal Symptoms among Cigarette Smokers

    Directory of Open Access Journals (Sweden)

    Arit M. Harvanko

    2017-01-01

    Full Text Available It is unknown whether first-generation electronic cigarettes reduce smoking urges and withdrawal symptoms following a 24 h deprivation period. This study tested whether a first-generation electronic cigarette reduces smoking urges and withdrawal symptoms in cigarette smokers. Following 24 h of tobacco deprivation, using a within-subjects design, eight nontreatment seeking tobacco cigarette smokers (3 females administered 10 puffs from a conventional cigarette or a first-generation electronic cigarette containing liquid with 0, 8 or 16 mg/ml nicotine. Conventional cigarettes ameliorated smoking urges and electronic cigarettes did not, regardless of nicotine concentration. First-generation electronic cigarettes may not effectively substitute for conventional cigarettes in reducing smoking urges, regardless of nicotine concentration.

  15. The Effect of Social Anxiety on Urge and Craving among Smokers with and without Anxiety Disorders

    Science.gov (United States)

    Kimbrel, Nathan A.; Morissette, Sandra B.; Gulliver, Suzy B.; Langdon, Kirsten J.; Zvolensky, Michael J.

    2014-01-01

    Background Despite the often social nature of smoking, relatively little research has been conducted on the relationship between smoking and social anxiety disorder (SAD). Method Participants (N = 99) included 34 smokers without current mental health disorders, 37 smokers with SAD, and 28 smokers who met criteria for other anxiety disorder diagnoses (e.g., panic disorder or generalized anxiety disorder, but not SAD). Nicotine and placebo patches were administered to participants in a counterbalanced manner across two assessment days. Urge and craving were assessed before and after a 5-hour nicotine absorption/deprivation period. Results Compared to smokers without current mental health disorders, smokers with SAD did not report greater nicotine dependence, but did endorse greater motivation to use nicotine to avoid negative outcomes. In addition, after controlling for demographic variables, smoking characteristics, pre-deprivation urge and craving, and other anxiety/depression symptoms, social anxiety symptoms uniquely predicted urge and craving in the placebo patch condition; however, social anxiety had no influence on urge and craving in the nicotine patch condition. Conclusions These findings suggest that one potential reason that smokers with SAD may have worse cessation outcomes is that they may experience higher levels of craving and urge to smoke during quit attempts. Thus, during a quit attempt, particularly in the absence of nicotine replacement therapy, smokers with SAD are likely to benefit from additional treatment aimed at managing or reducing their social anxiety symptoms. PMID:24331637

  16. Aging deteriorated perception of urge-to-cough without changing cough reflex threshold to citric acid in female never-smokers.

    Science.gov (United States)

    Ebihara, Satoru; Ebihara, Takae; Kanezaki, Masashi; Gui, Peijun; Yamasaki, Miyako; Arai, Hiroyuki; Kohzuki, Masahiro

    2011-06-28

    The effect of aging on the cognitive aspect of cough has not been studied yet. The purpose of this study is to investigate the aging effect on the perception of urge-to-cough in healthy individuals. Fourteen young, female, healthy never-smokers were recruited via public postings. Twelve elderly female healthy never-smokers were recruited from a nursing home residence. The cough reflex threshold and the urge-to-cough were evaluated by inhalation of citric acid. The cough reflex sensitivities were defined as the lowest concentration of citric acid that elicited two or more coughs (C2) and five or more coughs (C5). The urge-to-cough was evaluated using a modified the Borg scale. There was no significant difference in the cough reflex threshold to citric acid between young and elderly subjects. The urge-to-cough scores at the concentration of C2 and C5 were significantly smaller in the elderly than young subjects. The urge-to-cough log-log slope in elderly subjects (0.73 ± 0.71 point · L/g) was significantly gentler than those of young subjects (1.35 ± 0.53 point · L/g, p < 0.01). There were no significant differences in the urge-to-cough threshold estimated between young and elderly subjects. The cough reflex threshold did not differ between young and elderly subjects whereas cognition of urge-to-cough was significantly decreased in elderly subjects in female never-smokers. Objective monitoring of cough might be important in the elderly people.

  17. Viewing alcohol warning advertising reduces urges to drink in young adults: an online experiment.

    Science.gov (United States)

    Stautz, Kaidy; Marteau, Theresa M

    2016-07-08

    Tobacco counter-advertising is effective at promoting smoking cessation. Few studies have evaluated the impact of alcohol warning advertising on alcohol consumption and possible mechanisms of effect. This pilot study aimed to assess whether alcohol warning advertising is effective in reducing urges to drink alcohol, if emotional responses to advertising explain any such effect or perceived effectiveness, and whether effects differ among heavier drinkers. One hundred fifty-two young adult (aged 18-25) alcohol users completed an online experiment in which they were randomly assigned to view one of three sets of six advertisements: (i) alcohol warning; (ii) alcohol promoting; or (iii) advertisements for non-alcohol products. Urges to drink alcohol were self-reported post-exposure. Affective responses (pleasure and arousal) to each advertisement and perceived effectiveness of each advertisement were recorded. Typical level of alcohol consumption was measured as a potential effect modifier. Participants exposed to alcohol warning advertisements reported significantly lower urges to drink alcohol than those who viewed either alcohol promoting or non-alcohol advertisements. This effect was fully mediated by negative affective responses (displeasure) to the alcohol warning advertisements. Perceived effectiveness of alcohol warning advertisements was associated with high arousal responses. Impact of the advertisements was unaffected by typical level of alcohol consumption, although the study was not powered to detect anything other than large effects. In line with findings from the tobacco literature, alcohol warning advertisements that elicit negative affect reduce urges to drink alcohol. Their impact upon actual consumption awaits investigation.

  18. Daily relations among affect, urge, targeted naltrexone, and alcohol use in young adults.

    Science.gov (United States)

    Bold, Krysten W; Fucito, Lisa M; Corbin, William R; DeMartini, Kelly S; Leeman, Robert F; Kranzler, Henry R; O'Malley, Stephanie S

    2016-10-01

    Heavy drinking among young adults is a serious public health problem. Naltrexone, an opioid antagonist, has been shown to reduce drinking in young adults compared to placebo and can be taken on a targeted (i.e., as needed) basis. Understanding risk factors for drinking and naltrexone effects within-person in young adults may help to optimize the use of targeted naltrexone. The current study was a secondary analysis of daily diary data from 127 (n = 40 female) young adults (age 18-25) enrolled in a double-blind clinical trial of daily (25 mg) plus targeted (25 mg) naltrexone versus placebo. Hierarchical linear models were used to examine the effects of daily affect, urge, and taking targeted medication on same-day risk of drinking to intoxication (defined as estimated blood-alcohol-concentration, BAC ≥ .08 g%). Results indicated urge significantly mediated within-person positive affect-drinking relations on a daily level. Specifically, positive affect was associated with greater urge to drink, which in turn was associated with greater odds of BAC ≥ .08 g%. Furthermore, days of greater positive affect and urge were associated with taking a targeted dose of medication, which reduced the likelihood of intoxication by nearly 23% in the naltrexone group compared to placebo. Gender and family history of alcohol dependence were examined as moderators of these daily level effects. These results provide further evidence of naltrexone's ability to reduce alcohol consumption in young adults and identify potential within-person risk processes related to heavy drinking that could inform alcohol-related interventions for this population. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  19. A Comparison of Urge Intensity and the Probability of Tic Completion During Tic Freely and Tic Suppression Conditions.

    Science.gov (United States)

    Specht, Matt W; Nicotra, Cassandra M; Kelly, Laura M; Woods, Douglas W; Ricketts, Emily J; Perry-Parrish, Carisa; Reynolds, Elizabeth; Hankinson, Jessica; Grados, Marco A; Ostrander, Rick S; Walkup, John T

    2014-03-01

    Tic-suppression-based treatments (TSBTs) represent a safe and effective treatment option for Chronic Tic Disorders (CTDs). Prior research has demonstrated that treatment naive youths with CTDs have the capacity to safely and effectively suppress tics for prolonged periods. It remains unclear how tic suppression is achieved. The current study principally examines how effective suppression is achieved and preliminary correlates of the ability to suppress tics. Twelve youths, ages 10 to 17 years, with moderate-to-marked CTDs participated in an alternating sequence of tic freely and reinforced tic suppression conditions during which urge intensity and tic frequency were frequently assessed. Probability of tics occurring was half as likely following high-intensity urges during tic suppression (31%) in contrast to low-intensity urges during tic freely conditions (60%). Age was not associated with ability to suppress. Intelligence indices were associated with or trended toward greater ability to suppress tics. Attention difficulties were not associated with ability to suppress but were associated with tic severity. In contrast to our "selective suppression" hypothesis, we found participants equally capable of suppressing their tics regardless of urge intensity during reinforced tic suppression. Tic suppression was achieved with an "across-the-board" effort to resist urges. Preliminary data suggest that ability to suppress may be associated with general cognitive variables rather than age, tic severity, urge severity, and attention. Treatment naive youths appear to possess a capacity for robust tic suppression. TSBTs may bolster these capacities and/or enable their broader implementation, resulting in symptom improvement. © The Author(s) 2014.

  20. Sacral nerve root neuromodulation: an effective treatment for refractory urge incontinence.

    Science.gov (United States)

    Shaker, H S; Hassouna, M

    1998-05-01

    Sacral foramina implants have been recognized recently as a method for treatment of refractory urinary urge incontinence. We study the outcome of the procedure with in-depth analysis of the results of 18 implanted cases. Patients with urinary urge incontinence were subjected to percutaneous nerve evaluation of the S3 roots as a temporary screening test to determine response to neuromodulation. Satisfactory responders were implanted with permanent sacral root neuroprosthesis. The study design included comprehensive voiding diaries for 4 consecutive days twice as a baseline, 1 with percutaneous nerve evaluation screening, 1 after the percutaneous nerve evaluation, 1 at the 1, 3 and 6 post-implantation visits, and every 6 months thereafter. Uroflowmetry and quality of life questionnaires were performed at the same intervals. Urodynamic study was done as a baseline and 6 months after implantation of the neuroprosthesis. All 18 patients (16 women and 2 men) with refractory urge incontinence received a sacral foramina neuroprosthesis after demonstrating a good response to the percutaneous nerve evaluation. Average patient age at presentation was 42.3+/-3.3 years (range 22 to 67) and duration of urinary symptoms was 6.6+/-1.3 years (range 1.2 to 18.8). Average followup was 18.8 months (range 3 to 83). Neuromodulation in these patients showed a marked reduction in leakage episodes from 6.49 to 1.98 times per 24 hours and in the leakage severity score. Eight patients became completely dry and 4 had average leakage episodes of 1 or less daily. Patients showed as well a decrease in urinary frequency with an increase in functional bladder capacity. Associated pelvic pain improved substantially. Cystometrograms demonstrated increased volume at first sensation by 50% and increased cystometric capacity by 15% with the disappearance of uninhibited contractions in 1 of the 4 patients who presented with it preoperatively. There was also noticeable improvement in the quality of life

  1. Three European ministers visit CERN

    CERN Multimedia

    2007-01-01

    There have been three ministerial visits to CERN this month. Gediminas Kirkilas, Prime Minister of Lithuania, and Robert Aymar, CERN’s Director-General.On 2 July, the Prime Minister of Lithuania, Gediminas Kirkilas, was welcomed by CERN’s Director-General, Robert Aymar, before being taken on a visit of the ATLAS cavern at Point 2 and the LHC tunnel. Michal Sewerynski, Poland’s Minister for Science and Higher Education, and Robert Aymar, CERN’s Director-General.Ten days later, Poland’s Minister for Science and Higher Education, Michal Sewerynski, visited the CMS cavern and assembly hall and the LHC tunnel. He was also given a tour of the LHC Computer Centre and the CERN Control Centre. His visit was rounded off with a presentation of Polish companies involved in CERN’s activities, followed by a meeting with Polish personnel working at CERN. J�...

  2. Viewing alcohol warning advertising reduces urges to drink in young adults: an online experiment

    Directory of Open Access Journals (Sweden)

    Kaidy Stautz

    2016-07-01

    Full Text Available Abstract Background Tobacco counter-advertising is effective at promoting smoking cessation. Few studies have evaluated the impact of alcohol warning advertising on alcohol consumption and possible mechanisms of effect. This pilot study aimed to assess whether alcohol warning advertising is effective in reducing urges to drink alcohol, if emotional responses to advertising explain any such effect or perceived effectiveness, and whether effects differ among heavier drinkers. Methods One hundred fifty-two young adult (aged 18–25 alcohol users completed an online experiment in which they were randomly assigned to view one of three sets of six advertisements: (i alcohol warning; (ii alcohol promoting; or (iii advertisements for non-alcohol products. Urges to drink alcohol were self-reported post-exposure. Affective responses (pleasure and arousal to each advertisement and perceived effectiveness of each advertisement were recorded. Typical level of alcohol consumption was measured as a potential effect modifier. Results Participants exposed to alcohol warning advertisements reported significantly lower urges to drink alcohol than those who viewed either alcohol promoting or non-alcohol advertisements. This effect was fully mediated by negative affective responses (displeasure to the alcohol warning advertisements. Perceived effectiveness of alcohol warning advertisements was associated with high arousal responses. Impact of the advertisements was unaffected by typical level of alcohol consumption, although the study was not powered to detect anything other than large effects. Conclusions In line with findings from the tobacco literature, alcohol warning advertisements that elicit negative affect reduce urges to drink alcohol. Their impact upon actual consumption awaits investigation.

  3. Can't Curb the Urge to Move? Living with Restless Legs Syndrome

    Science.gov (United States)

    ... Special Issues Subscribe October 2012 Print this issue Can’t Curb the Urge to Move? Living With ... for people with restless legs syndrome. The condition can cause throbbing, pulling or creeping sensations in the ...

  4. First- versus second-generation electronic cigarettes: predictors of choice and effects on urge to smoke and withdrawal symptoms.

    Science.gov (United States)

    Dawkins, Lynne; Kimber, Catherine; Puwanesarasa, Yasothani; Soar, Kirstie

    2015-04-01

    To (1) estimate predictors of first- versus second-generation electronic cigarette (e-cigarette) choice; and (2) determine whether a second-generation device was (i) superior for reducing urge to smoke and withdrawal symptoms (WS) and (ii) associated with enhanced positive subjective effects. Mixed-effects experimental design. Phase 1: reason for e-cigarette choice was assessed via questionnaire. Phase 2: participants were allocated randomly to first- or second-generation e-cigarette condition. Urge to smoke and WS were measured before and 10 minutes after taking 10 e-cigarette puffs. University of East London, UK. A total of 97 smokers (mean age 26; standard deviation 8.7; 54% female). Single-item urge to smoke scale to assess craving and the Mood and Physical Symptoms Scale (MPSS) to assess WS. Subjective effects included: satisfaction, hit, 'felt like smoking' and 'would use to stop smoking' (yes versus no response). Equal numbers chose each device, but none of the predictor variables (gender, age, tobacco dependence, previous e-cigarette use) accounted for choice. Only baseline urge to smoke/WS predicted urge to smoke/WS 10 minutes after use (B =0.38; P E-cigarette device was not a significant predictor. Those using the second-generation device were more likely to report satisfaction and use in a quit attempt (χ(2)  = 12.10, P =0.001 and χ(2)  = 5.53, P =0.02). First- and second-generation electronic cigarettes appear to be similarly effective in reducing urges to smoke during abstinence, but second-generation devices appear to be more satisfying to users. © 2014 Society for the Study of Addiction.

  5. Repetitive urges to inflict burns: An unusual presentation of impulse control disorder.

    Science.gov (United States)

    Pal, Arghya; Parmar, Arpit; Pattanayak, Raman Deep

    2016-01-01

    Impulse control disorders (ICDs) are characterized by an inability to resist an intense impulse or drive to perform a particular act that is excessive and/or harmful to self/others. Till date, there is no published report of an ICD presenting with repetitive urges to inflict burns. We describe the case of an adult male in regular follow-up for 6 months who presented with intense, irresistible, and repetitive urges and acts of causing burns on his skin for past 1 year. The phenomenology shared the core qualities described for ICDs and patient showed adequate response to treatment. The case report describes an unusual type of ICD classifiable as not otherwise specified. More clinical and research attention is warranted toward ICDs in general, with implications for ICD-11.

  6. Repetitive urges to inflict burns: An unusual presentation of impulse control disorder

    Directory of Open Access Journals (Sweden)

    Arghya Pal

    2016-01-01

    Full Text Available Impulse control disorders (ICDs are characterized by an inability to resist an intense impulse or drive to perform a particular act that is excessive and/or harmful to self/others. Till date, there is no published report of an ICD presenting with repetitive urges to inflict burns. We describe the case of an adult male in regular follow-up for 6 months who presented with intense, irresistible, and repetitive urges and acts of causing burns on his skin for past 1 year. The phenomenology shared the core qualities described for ICDs and patient showed adequate response to treatment. The case report describes an unusual type of ICD classifiable as not otherwise specified. More clinical and research attention is warranted toward ICDs in general, with implications for ICD-11.

  7. Origin of symbol-using systems: speech, but not sign, without the semantic urge.

    Science.gov (United States)

    Sereno, Martin I

    2014-09-19

    Natural language--spoken and signed--is a multichannel phenomenon, involving facial and body expression, and voice and visual intonation that is often used in the service of a social urge to communicate meaning. Given that iconicity seems easier and less abstract than making arbitrary connections between sound and meaning, iconicity and gesture have often been invoked in the origin of language alongside the urge to convey meaning. To get a fresh perspective, we critically distinguish the origin of a system capable of evolution from the subsequent evolution that system becomes capable of. Human language arose on a substrate of a system already capable of Darwinian evolution; the genetically supported uniquely human ability to learn a language reflects a key contact point between Darwinian evolution and language. Though implemented in brains generated by DNA symbols coding for protein meaning, the second higher-level symbol-using system of language now operates in a world mostly decoupled from Darwinian evolutionary constraints. Examination of Darwinian evolution of vocal learning in other animals suggests that the initial fixation of a key prerequisite to language into the human genome may actually have required initially side-stepping not only iconicity, but the urge to mean itself. If sign languages came later, they would not have faced this constraint.

  8. In e-mail to students, Annan urges communication to build understanding

    CERN Multimedia

    2003-01-01

    "Using the original computer on which the Internet was created, United Nations Secretary-General Kofi Annan today sent an electronic message to young people around the world urging them to keep communicating with each other to build bridges of understanding between cultures and societies" (1 page)

  9. URG4/URGCP enhances the angiogenic capacity of human hepatocellular carcinoma cells in vitro via activation of the NF-κB signaling pathway

    International Nuclear Information System (INIS)

    Xing, Sizhong; Zhang, Bing; Hua, Ruixi; Tai, William Chi-shing; Zeng, Zhirong; Xie, Binhui; Huang, Chenghui; Xue, Jisu; Xiong, Shiqiu; Yang, Jianyong; Liu, Side; Li, Heping

    2015-01-01

    Angiogenesis is essential for tumor growth. Hepatocellular carcinoma (HCC) is characterized by hypervascularity; high levels of angiogenesis are associated with poor prognosis and a highly invasive phenotype in HCC. Up-regulated gene-4 (URG4), also known as upregulator of cell proliferation (URGCP), is overexpressed in multiple tumor types and has been suggested to act as an oncogene. This study aimed to elucidate the effect of URG4/URGCP on the angiogenic capacity of HCC cells in vitro. Expression of URG4/URGCP in HCC cell lines and normal liver epithelial cell lines was examined by Western blotting and quantitative real-time PCR. URG4/URGCP was stably overexpressed or transiently knocked down using a shRNA in two HCC cell lines. The human umbilical vein endothelial cell (HUVEC) tubule formation and Transwell migration assays and chicken chorioallantoic membrane (CAM) assay were used to examine the angiogenic capacity of conditioned media from URG4/URGCP-overexpressing and knockdown cells. A luciferase reporter assay was used to examine the transcriptional activity of nuclear factor kappa – light – chain - enhancer of activated B cells (NF-κB). NF-κB was inhibited by overexpressing degradation-resistant mutant inhibitor of κB (IκB)-α. Expression of vascular endothelial growth factor C (VEGFC), tumor necrosis factor-α (TNFα), interleukin (IL)-6, IL-8 and v-myc avian myelocytomatosis viral oncogene homolog (MYC) were examined by quantitative real-time PCR; VEGFC protein expression was analyzed using an ELISA. URG4/URGCP protein and mRNA expression were significantly upregulated in HCC cell lines. Overexpressing URG4/URGCP enhanced - while silencing URG4/URGCP decreased - the capacity of HCC cell conditioned media to induce HUVEC tubule formation and migration and neovascularization in the CAM assay. Furthermore, overexpressing URG4/URGCP increased - whereas knockdown of URG4/URGCP decreased - VEGFC expression, NF-κB transcriptional activity, the levels

  10. Projecto - IV Expedição Científica do Departamento de Biologia - Flores 1989.

    OpenAIRE

    Martins, António M. de Frias; Furtado, Duarte; Brum, João M. M.; Almeida, Luís Mexia de

    1989-01-01

    IV Expedição Científica do Departamento de Biologia - Flores 1989 (Projecto). A zona costeira açoreana é sem dúvida uma verdadeira fronteira entre o mundo terrestre e marinho, representando um dos ecossistemas mais ricos do arquipélago. Mal descrita e pouco conhecida, esta pequena parcela com cerca de cinco a sete milhões de anos de idade é o meio mais transformado por numerosos factores inerentes a presença do homem. São numerosos os pontos do Arquipélago em que o meio marinho é praticame...

  11. Expedient preparation of nazlinine and a small library of indole alkaloids using flow electrochemistry as an enabling technology.

    Science.gov (United States)

    Kabeshov, Mikhail A; Musio, Biagia; Murray, Philip R D; Browne, Duncan L; Ley, Steven V

    2014-09-05

    An expedient synthesis of the indole alkaloid nazlinine is reported. Judicious choice of flow electrochemistry as an enabling technology has permitted the rapid generation of a small library of unnatural relatives of this biologically active molecule. Furthermore, by conducting the key electrochemical Shono oxidation in a flow cell, the loading of electrolyte can be significantly reduced to 20 mol % while maintaining a stable, broadly applicable process.

  12. A pilot randomised controlled trial of the feasibility of using body scan and isometric exercises for reducing urge to smoke in a smoking cessation clinic

    Directory of Open Access Journals (Sweden)

    Aveyard Paul

    2008-10-01

    Full Text Available Abstract Background The main cause of relapse in smokers attempting to quit is inability to resist urges to smoke. Pharmacotherapy ameliorates but does not entirely prevent urges to smoke when abstinent, so other methods to resist urges to smoke might be helpful. Exercise is effective, but aerobic exercise is often impractical when urges strike. Two techniques, body scan and isometric exercise, have been shown to reduce urge intensity and nicotine withdrawal symptoms in temporarily abstinent smokers. It is unclear whether they would be used or effective in typical smokers attempting to quit. Methods In a pilot trial set in a UK smoking cessation clinic, 20 smokers were randomised to receive emails containing .mp3 files and .pdf illustrations of the instructions for doing the body scan and isometric exercises. Twenty smokers received no other intervention, although all 40 were receiving weekly behavioural support and nicotine replacement therapy. Carbon monoxide confirmed abstinence, nicotine withdrawal symptoms, urges to smoke, and use of the techniques to resist urges were recorded weekly for four weeks after quit day. Results 60–80% of quitters reported using the isometric exercises each week and 40–70% reported using the body scan to deal with urges. On average, these techniques were rated as 'slightly helpful' for controlling the urges. There were no large or significant differences in withdrawal symptoms or urge intensity between the two groups. The risk ratio and 95% confidence interval for exercises compared with controls for prolonged confirmed abstinence at four weeks was 0.82 (0.44–1.53. 81% of quitters intended to continue using isometric exercises and 25% body scan, while 81% and 50% respectively would recommend using these techniques to others trying to stop. Conclusion Isometric exercises, and to a lesser extent body scan, were popular and perceived as somewhat helpful by quitters. The trial showed that these techniques were

  13. Characterization of urge to cough and cough symptoms associated with the common cold: results of a US internet survey.

    Science.gov (United States)

    Eccles, Ron; Dicpinigaitis, Peter; Turner, Ronald B; Druce, Howard M; Adeleke, Maryann; Mann, Ashley L

    2016-06-01

    Our knowledge of cough physiology is limited despite years of study. Even less is known about the sensation of urge to cough. Given that limited clinical data are available about urge to cough and cough attributes during a common cold, we sought to gain insights into experiences and perceptions related to these symptoms. An internet survey consisting of 51 questions was fielded in the United States. Eligible survey participants included men and women aged 18 years and older who had suffered from a cold with cough within the three months preceding the survey. Participants who confirmed suffering from recurrent cough, asthma, chronic bronchitis, chronic obstructive pulmonary disease, cystic fibrosis, or gastrointestinal reflux were excluded. Of 19,530 initial respondents, 8011 had a cold in the past three months. Of these, 6484 (81%) had experienced cough symptoms; 2708 respondents with cough due to cold and no exclusionary condition made up the analysis sample. Most respondents (62%) reported that cough developed one to two days after the onset of cold symptoms, and 45% felt that cough worsened their other cold symptoms. In 69% of respondents, cough outlasted other cold symptoms. Urge to cough was reported by 98% of respondents, and among these respondents, 64% described it as uncontrollable and 65% rated severity as moderate. More than half of respondents (57%) considered the sensation of urge to cough and the act of coughing as equally bothersome. Although urge to cough and inability to control cough were the most bothersome aspects of cough due to cold, few (<20%) respondents asked healthcare providers for treatment recommendations. Symptoms of urge to cough and cough are common and have a significant impact on cold sufferers. Understanding attributes of these symptoms may provide insights for effective management and the development of novel treatment strategies.

  14. Influence of negative affect on selective attention to smoking-related cues and urge to smoke in cigarette smokers.

    Science.gov (United States)

    Bradley, Brendan P; Garner, Matthew; Hudson, Laura; Mogg, Karin

    2007-07-01

    According to recent models of addiction, negative affect plays an important role in maintaining drug dependence. The study investigated the effect of negative mood on attentional biases for smoking-related cues and smoking urge in cigarette smokers. Eye movements to smoking-related and control pictures, and manual response times to probes, were recorded during a visual probe task. Smoking urges and mood were assessed by self-report measures. Negative affect was manipulated experimentally as a within-participants independent variable; that is, each participant received negative and neutral mood induction procedures, in counterbalanced order in separate sessions, before the attentional task. There were two groups of participants: smokers and nonsmokers. Smokers showed (i) a greater tendency to shift gaze initially towards smoking-related cues, and (ii) greater urge to smoke when they were in negative mood compared with neutral mood. Manual response time data suggested that smokers showed a greater tendency than nonsmokers to maintain attention on smoking-related cues, irrespective of mood. The results offer partial support for the view that negative mood increases selective attention to drug cues, and urge to smoke, in smokers. The findings are discussed in relation to an affective processing model of negative reinforcement in drug dependence.

  15. Virtual reality jogging as a novel exposure paradigm for the acute urge to be physically active in patients with eating disorders: Implications for treatment.

    Science.gov (United States)

    Paslakis, Georgios; Fauck, Vanessa; Röder, Kathrin; Rauh, Elisabeth; Rauh, Manfred; Erim, Yesim

    2017-11-01

    The acute urge to be physically active is a relevant clinical phenomenon in patients suffering from eating disorders. In this study with n = 20 female patients with anorexia nervosa and n = 10 female patients with bulimia nervosa, a virtual reality (VR) jogging paradigm was applied as a novel highly immersive 3D exposure paradigm. Patients were asked to rate their acute urge to be physically active during the exposure procedure. A 10-item self-report questionnaire (smQ) was developed to capture the cognitive, emotional, and behavioral aspects of the acute urge to move. We hypothesized that exposure would lead to habituation of the urge to be physically active. We also hypothesized that leptin levels would be associated with the degree of the subjective urge to be physically active, while habituation would be associated with a decrease in stress hormones (α-amylase, cortisol, and cortisone in saliva). A statistically significant change in subjective scores in the smQ from baseline to postexposure was seen. Our novel VR paradigm may serve as a therapeutic tool for exposure and habituation of the urge of acutely engaging in physical activity in patients with eating disorders. © 2017 Wiley Periodicals, Inc.

  16. Categorical Confusion? The Strategic Implications of Recognizing Challenges Either as Irregular or Traditional

    Science.gov (United States)

    2012-02-01

    strategies, and even tactics, were seriously flawed systemically. But the urge to categorize and clarify, after the fashion of Victorian entomologists...strategic think- ing today is a confused jumble of briefly fashionable buzzwords of uncertain authority or merit. This con- 2 fusion of ideas rests and...concep- tual subject permits. 1. Clarity in definition matters greatly. It may be fashionable and expedient to deploy fuzzy blurring descriptors like

  17. Self-relevant disgust and self-harm urges in patients with borderline personality disorder and depression: a pilot study with a newly designed psychological challenge.

    Directory of Open Access Journals (Sweden)

    Sawsan Abdul-Hamid

    Full Text Available Borderline personality disorder (BPD is a common psychiatric condition associated with self-harm. Self-harm is poorly understood and there is currently no treatment for acute presentations with self-harm urges.By using a new task (Self-relevant Task; SRT, to explore emotions related to one's own person (PERSON task and body (BODY task, to study the correlations of these emotions, specifically disgust, with self-harm urge level changes, and to test the task's potential to be developed into an experimental model of self-harming for treatment trials.17 BPD patients, 27 major depressive disorder (MDD patients, and 25 healthy volunteers performed the SRT. Emotion labels were extracted from task narratives and disgust and self-harm urge level changes measured by visual analogue scales. We used validated rating scales to measure symptom severity.The SRT was effective at inducing negative emotions and self-harm urge changes. Self-harm urge changes correlated with borderline symptom severity. Post-task disgust levels on the visual analogue scales were higher in BPD patients than in healthy controls in the PERSON task, and higher than in both control groups in the BODY task. Changes in disgust levels during the task were significantly greater in the patient groups. Post-task disgust levels or changes in disgust were not associated with self-harm urge changes (except the latter in MDD in the PERSON task, but self-harm urge changes and disgust (but no other emotion narrative labels were on a whole sample level.Although associations with the analogue scale measures were not significant, self-disgust reported in the narrative of patients may be associated with a higher probability of self-harm urges. Further research with larger sample sizes is needed to confirm this relationship and to examine whether reducing self-disgust could reduce self-harm urges. The SRT was effective and safe, and could be standardized for experimental studies.

  18. Point-of-Sale Cigarette Marketing, Urge to Buy Cigarettes, and Impulse Purchases of Cigarettes: Results From a Population-Based Survey.

    Science.gov (United States)

    Siahpush, Mohammad; Shaikh, Raees A; Hyland, Andrew; Smith, Danielle; Sikora Kessler, Asia; Meza, Jane; Wan, Neng; Wakefield, Melanie

    2016-05-01

    Our aim was to examine the association of exposure to point-of-sale (POS) cigarette marketing for one's regular brand, as well as any brand of cigarettes, with the urge to buy cigarettes and frequency of impulse purchases of cigarettes. Nine hundred ninety-nine smokers in Omaha, Nebraska were interviewed via telephone. Cigarette marketing was measured by asking respondents questions about noticing pack displays, advertisements, and promotions such as discounts for their regular brand as well as any brand of cigarettes in their neighborhoods stores. We measured urge to buy cigarettes with the question "When you are in a store in your neighborhood that sells tobacco products, how often do you get an urge to buy cigarettes?" We measured frequency of impulse purchases of cigarettes with the question "When you are shopping in a store in your neighborhood for something other than cigarettes, how often do you decide to buy cigarettes?" We estimated ordinary least squares linear regression models to address the study aim. Higher levels of POS marketing for one's regular brand and any brands of cigarettes were associated with more frequent urges to buy (P purchases of cigarettes (P = .01 and P = .013, respectively), after adjusting for covariates. Exposure to POS marketing for one's own brand of cigarette as well as any brand is associated with urges to buy and impulse purchases of cigarettes. Existing studies on the association of POS cigarette marketing with urge to buy and an impulse purchase of cigarettes only focus on cigarette pack displays, not on advertisements and promotions. Also, these studies make no distinction between marketing for the smokers' regular brand and any brand of cigarettes. This study found that Exposure to POS marketing for one's own brand of cigarette as well as any brand is associated with urges to buy and impulse purchases of cigarettes. Our findings can provide part of the evidence-base needed by the Food and Drug Administration or local

  19. Urinary urge seizure semiology localization by intracranial monitoring

    Science.gov (United States)

    Rengarajan, Ronak; Shamim, Sadat

    2018-01-01

    ABSTRACT Seizures may present with many different symptom complexes. Seizure semiologies have localization value when contemplating surgical therapies. Epilepsy presenting as a desire to micturate is exceedingly rare, with only a handful of published cases. We present a patient who had initially unexplained childhood urinary urge that progressed into lapses of memory and confusion that was eventually diagnosed as epilepsy in adulthood. Due to refractoriness to medical management, our patient's epileptic focus was localized through both noninvasive and invasive subdural electrode arrays to the nondominant medial temporal lobe and successfully treated with an amygdalohippocampectomy. Only one other case of ictal urinary urgency seizures has been recorded with intracranial electroencephalogram monitoring in the literature. PMID:29686574

  20. Urinary urge seizure semiology localization by intracranial monitoring.

    Science.gov (United States)

    Rengarajan, Ronak; Shamim, Sadat

    2018-01-01

    Seizures may present with many different symptom complexes. Seizure semiologies have localization value when contemplating surgical therapies. Epilepsy presenting as a desire to micturate is exceedingly rare, with only a handful of published cases. We present a patient who had initially unexplained childhood urinary urge that progressed into lapses of memory and confusion that was eventually diagnosed as epilepsy in adulthood. Due to refractoriness to medical management, our patient's epileptic focus was localized through both noninvasive and invasive subdural electrode arrays to the nondominant medial temporal lobe and successfully treated with an amygdalohippocampectomy. Only one other case of ictal urinary urgency seizures has been recorded with intracranial electroencephalogram monitoring in the literature.

  1. Work and Non-Work Physical Activity Predict Real-Time Smoking Level and Urges in Young Adults.

    Science.gov (United States)

    Nadell, Melanie J; Mermelstein, Robin J; Hedeker, Donald; Marquez, David X

    2015-07-01

    Physical activity (PA) and smoking are inversely related. However, evidence suggests that some types of PA, namely work-related PA, may show an opposite effect. Despite growing knowledge, there remains a paucity of studies examining the context of these behaviors in naturalistic settings or in young adults, a high-risk group for escalation. Participants were 188 young adults (mean age = 21.32; 53.2% female; 91% current smokers) who participated in an electronic diary week to assess daily smoking and urges and a PA recall to examine daily PA. PA was coded into non-work-related and work-related activity to examine differential effects. We considered both participants' weekly average PA and their daily deviations from their average. Mixed-effects regression models revealed that higher weekly average non-work PA was associated with lower smoking level and urges. Daily deviations in non-work PA did not predict urges; however, increased daily non-work PA relative to participants' weekly average was associated with lower smoking for females but higher levels for males. Regarding work PA, only higher weekly average work PA was associated with higher smoking level for both genders; work PA did not predict urges. Results extend previous literature by documenting differential associations between non-work and work PA and young adult smoking and suggest that young adults engaged in work PA should be considered a high-risk group for escalation. Findings provide theoretical and clinical implications for the use of PA in intervention and highlight the necessity of considering PA as a multidimensional construct when examining its links to health behavior. © The Author 2014. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  2. The contribution of hysterectomy to the occurrence of urge and stress urinary incontinence symptoms

    NARCIS (Netherlands)

    van der Vaart, C. H.; van der Bom, J. G.; de Leeuw, J. R. J.; Roovers, J. P. W.; Heintz, A. P. M.

    2002-01-01

    OBJECTIVE: To study the contribution of hysterectomy to the occurrence of urge-or stress urinary incontinence symptoms. DESIGN: A population-based, cross-sectional cohort study conducted in 1999. SETTING: A university medical centre in The Netherlands. POPULATION: Random sample of 2322 women,

  3. Explicit and inferred motives for nonsuicidal self-injurious acts and urges in borderline and avoidant personality disorders.

    Science.gov (United States)

    Snir, Avigal; Rafaeli, Eshkol; Gadassi, Reuma; Berenson, Kathy; Downey, Geraldine

    2015-07-01

    Nonsuicidal self-injury (NSSI) is a perplexing phenomenon that may have differing motives. The present study used experience sampling methods (ESM) which inquired explicitly about the motives for NSSI, but also enabled a temporal examination of the antecedents/consequences of NSSI; these allow us to infer other motives which were not explicitly endorsed. Adults (n = 152, aged 18-65) with borderline personality disorder (BPD), avoidant personality disorder (APD), or no psychopathology participated in a 3-week computerized diary study. We examined 5 classes of explicit motives for engaging in NSSI, finding support primarily for internally directed rather than interpersonally directed ones. We then used multilevel regression to examine changes in affect, cognition, and behavior surrounding moments of NSSI acts/urges compared with control moments (i.e., without NSSI). We examined changes in 5 scales of inferred motives, designed to correspond to the 5 classes of explicit motives. The results highlight differing motives for NSSI among individuals with BPD and APD, with some similarities (mostly in the explicit motives) and some differences (mostly in the inferred motives) between the disorders. Despite their infrequent explicit endorsement, fluctuations in interpersonally oriented scales were found surrounding NSSI acts/urges. This highlights the need to continue attending to interpersonal aspects of NSSI in research and in clinical practice. Additionally, NSSI urges, like acts, were followed by decline in affective/interpersonal distress (although in a delayed manner). Thus, interventions that build distress tolerance and enhance awareness for affective changes, and for antecedent/consequence patterns in NSSI, could help individuals resist the urge to self-injure. (c) 2015 APA, all rights reserved).

  4. Thought suppression, impaired regulation of urges, and Addiction-Stroop predict affect-modulated cue-reactivity among alcohol dependent adults.

    Science.gov (United States)

    Garland, Eric L; Carter, Kristin; Ropes, Katie; Howard, Matthew O

    2012-01-01

    Abstinent alcohol dependent individuals commonly employ thought suppression to cope with stress and intrusive cognitions about alcohol. This strategy may inadvertently bias attention towards alcohol-related stimuli while depleting neurocognitive resources needed to regulate urges, manifested as decreased heart rate variability (HRV) responsivity to alcohol cues. The present study tested the hypothesis that trait and state thought suppression, impaired regulation of urges, and alcohol attentional bias as measured by the Addiction-Stroop would have significant effects on the HRV responsivity of 58 adults in residential treatment for alcohol dependence (mean age=39.6 ± 9.4, 81% female) who participated in an affect-modulated cue-reactivity protocol. Regression analyses controlling for age, level of pre-treatment alcohol consumption, and baseline HRV indicated that higher levels of trait thought suppression, impaired regulation of alcohol urges, and attentional fixation on alcohol cues were associated with lower HRV responsivity during stress-primed alcohol cue-exposure. Moreover, there was a significant state × trait suppression interaction on HRV cue-responsivity, such that alcohol dependent persons reporting high levels of state and trait suppression exhibited less HRV during cue-exposure than persons reporting low levels of state and trait suppression. Results suggest that chronic thought suppression taxes regulatory resources reflected in reduced HRV responsivity, an effect that is particularly evident when high trait suppressors engage in intensive suppression of drinking-related thoughts under conditions of stress. Treatment approaches that offer effective alternatives to the maladaptive strategy of suppressing alcohol urges may be crucial for relapse prevention. Copyright © 2011 Elsevier B.V. All rights reserved.

  5. Relações comerciais e diplomáticas Anglo-africanas durante a expedição ao Níger de 1854

    Directory of Open Access Journals (Sweden)

    Alexsander Lemos de Almeida Gebara

    2016-08-01

    Full Text Available Resumo O artigo procura compreender a expedição britânica nos rios Niger e Benue em 1854 num contexto de transformação nas relações políticas e econômicas da Grã Bretanha com o interior da África Ocidental. Tal empreendimento ficou marcado pela ausência de mortes por febres tropicais e deixou vários registros, dentre eles relatos de viagem e a correspondência entre seus agentes e o Foreign Office e o Colonial Office que compõe o corpo de fontes deste artigo. Especial atenção é dedicada aos termos e formas das trocas comerciais realizadas com os africanos diretamente ao longo da viagem e às condições nas quais estes relacionamentos foram estabelecidos. Assim, procura-se por um lado, compreender a expedição como parte de um de um processo de ampliação da presença europeia no interior e, por outro lado, refletir sobre as estratégias africanas em diálogo com as transformações econômicas na bacia Atlântica em meados do século XIX.

  6. Nicotine delivery, tolerability and reduction of smoking urge in smokers following short-term use of one brand of electronic cigarettes.

    Science.gov (United States)

    D'Ruiz, Carl D; Graff, Donald W; Yan, X Sherwin

    2015-09-30

    This randomized, partially single-blinded, 6-period crossover clinical study of adult smokers compared the nicotine pharmacokinetics, impacts on smoking urge and tolerability of various formulations of one brand of e-cigarettes with that of a tobacco cigarette. Five e-cigarettes with different e-liquid formulations containing 1.6 % and 2.4 % nicotine and a conventional tobacco cigarette were randomized among 24 subjects under two exposure sessions consisting of a 30-min controlled and a one-hour ad lib use period to assess plasma nicotine levels, impacts on smoking urge and adverse events. The 30-min controlled use session comprised an intensive use of the e-cigarettes with a total of 50 puffs taken every 30 s for comparison to a single conventional cigarette having a typical machine-measured nicotine yield (~0.8 mg). Ad lib product use conditions provided insight into more naturalistic product use behaviors and their accompanying smoking urge reductions. Adverse events (AEs) were assessed by the Principal Investigator. Significant (p e-cigarette use and significant (p E-cigarette and cigarette nicotine plasma levels were comparable for up to one hour of use. After both sessions (90 min), nicotine exposure was the highest for the cigarette, with all e-cigarettes showing 23 % to 53 % lower plasma concentrations. During controlled use, peak reduction in smoking urge for e-cigs occurred later than for the cigarette. After completion of both sessions, significant smoking urge reduction persisted for most of the tested e-cigarettes, albeit at levels lower than that provided by the tobacco cigarette. Nicotine content, vehicle differences, and the presence of menthol did not significantly affect smoking urge reduction by the e-cigarettes. No subjects were discontinued due to AEs. The most frequently reported AEs events included cough, throat irritation, headache, and dizziness. Blood plasma nicotine levels obtained from short-term use of e-cigarettes containing 1

  7. Sacral Nerve Stimulation For Urinary Urge Incontinence, Urgency-Frequency, Urinary Retention, and Fecal Incontinence

    Science.gov (United States)

    2005-01-01

    Executive Summary Objective The aim of this review was to assess the effectiveness, safety, and cost of sacral nerve stimulation (SNS) to treat urinary urge incontinence, urgency-frequency, urinary retention, and fecal incontinence. Background: Condition and Target Population Urinary urge incontinence, urgency-frequency, urinary retention, and fecal incontinence are prevalent, yet rarely discussed, conditions. They are rarely discussed because patients may be uncomfortable disclosing their symptoms to a health professional or may be unaware that there are treatment options for these conditions. Briefly, urge incontinence is an involuntary loss of urine upon a sudden urge. Urgency-frequency is an uncontrollable urge to void, which results in frequent, small-volume voids. People with urgency-frequency may or may not also experience chronic pelvic pain. Urinary retention refers to the inability to void despite having the urge to void. It can be caused by a hypocontractile detrusor (weak or no bladder muscle contraction) or obstruction due to urethral overactivity. Fecal incontinence is a loss of voluntary bowel control. The prevalence of urge incontinence, urgency-frequency, and urinary retention in the general population is 3.3% to 8.2%, and the prevalence of fecal incontinence is 1.4% to 1.9%. About three-quarters of these people will be successfully treated by behaviour and/or drug therapy. For those who do not respond to these therapies, the options for treatment are management with diapers or pads, or surgery. The surgical procedures are generally quite invasive, permanent, and are associated with complications. Pads and/or diapers are used throughout the course of treatment as different therapies are tried. Patients who respond successfully to treatment may still require pads or diapers, but to a lesser extent. The Technology Being Reviewed: Sacral Nerve Stimulation Sacral nerve stimulation is a procedure where a small device attached to an electrode is

  8. Does Vaping in E-Cigarette Advertisements Affect Tobacco Smoking Urge, Intentions, and Perceptions in Daily, Intermittent, and Former Smokers?

    Science.gov (United States)

    Maloney, Erin K; Cappella, Joseph N

    2016-01-01

    Visual depictions of vaping in electronic cigarette advertisements may serve as smoking cues to smokers and former smokers, increasing urge to smoke and smoking behavior, and decreasing self-efficacy, attitudes, and intentions to quit or abstain. After assessing baseline urge to smoke, 301 daily smokers, 272 intermittent smokers, and 311 former smokers were randomly assigned to view three e-cigarette commercials with vaping visuals (the cue condition) or without vaping visuals (the no-cue condition), or to answer unrelated media use questions (the no-ad condition). Participants then answered a posttest questionnaire assessing the outcome variables of interest. Relative to other conditions, in the cue condition, daily smokers reported greater urge to smoke a tobacco cigarette and a marginally significantly greater incidence of actually smoking a tobacco cigarette during the experiment. Former smokers in the cue condition reported lower intentions to abstain from smoking than former smokers in other conditions. No significant differences emerged among intermittent smokers across conditions. These data suggest that visual depictions of vaping in e-cigarette commercials increase daily smokers' urge to smoke cigarettes and may lead to more actual smoking behavior. For former smokers, these cues in advertising may undermine abstinence efforts. Intermittent smokers did not appear to be reactive to these cues. A lack of significant differences between participants in the no-cue and no-ad conditions compared to the cue condition suggests that visual depictions of e-cigarettes and vaping function as smoking cues, and cue reactivity is the mechanism through which these effects were obtained.

  9. Refinement of Foam Backfill Technology for Expedient Airfield Damage Repair; Phase 2: Development of Prototype Foam Dispensing Equipment and Improved Tactics, Techniques and Procedures

    Science.gov (United States)

    2017-12-01

    ER D C TR -1 7- 14 U.S. Air Force Rapid Airfield Damage Repair Modernization Program Refinement of Foam Backfill Technology for...Backfill Technology for Expedient Airfield Damage Repair Phase II: Development of Prototype Foam Dispensing Equipment and Improved Tactics...procedures (TTPs) for rapid airfield damage repair (RADR) using foam backfill technology . Three different prototype foam dispensing systems were

  10. Vestibulopatia por lesão endovascular em cateterismo de urgência

    OpenAIRE

    Simoceli, Lucinda; Sguillar, Danilo Anunciatto; Santos, Henrique Mendes Paiva; Caputti, Camilla

    2012-01-01

    OBJETIVO: O objetivo deste relato de caso é descrever uma causa incomum de vestibulopatia periférica associada à perda auditiva unilateral em paciente idoso pós- cateterismo de urgência. RELATO DE CASO: Paciente do gênero masculino, 82 anos, submetido à correção de aneurisma roto de aorta abdominal, no intra-operatório sofreu infarto agudo do miocárdio necessitando de angioplastia primária. Após alta hospitalar refere queixa de hipoacusia acentuada à direita e vertigem incapacitante, sem sina...

  11. Validation of the Brazilian version of Questionnaire of Smoking Urges-Brief

    OpenAIRE

    Araujo, Renata Brasil; Oliveira, Margareth da Silva; Moraes, João Feliz Duarte; Pedroso, Rosemeri Siqueira; Port, Franciny; Castro, Maria da Graça Tanori de

    2007-01-01

    CONTEXTO: A avaliação do craving (ou fissura) é muito importante no tratamento do tabagismo. OBJETIVO: O objetivo desta pesquisa foi validar a versão brasileira do Questionnaire of Smoking Urges-Brief (QSU-B). MÉTODOS: O delineamento foi experimental, e seus participantes foram divididos, aleatoriamente, em grupos de zero, 30 e 60 minutos de abstinência do tabaco. A amostra foi de 201 sujeitos (134 mulheres e 67 homens), entre 18 e 65 anos (M = 38,15), e os instrumentos aplicados, além do QSU...

  12. Transcutaneous stimulation of the posterior tibial nerve for treating refractory urge incontinence of idiopathic and neurogenic origin.

    Science.gov (United States)

    Valles-Antuña, C; Pérez-Haro, M L; González-Ruiz de L, C; Quintás-Blanco, A; Tamargo-Diaz, E M; García-Rodríguez, J; San Martín-Blanco, A; Fernandez-Gomez, J M

    2017-09-01

    To assess the efficacy of treatment with transcutaneous posterior tibial nerve stimulation (TPTNS) in patients with urge urinary incontinence, of neurogenic or nonneurogenic origin, refractory to first-line therapeutic options. We included 65 patients with urge urinary incontinence refractory to medical treatment. A case history review, a urodynamic study and a somatosensory evoked potentials (SEP) study were conducted before the TPTNS, studying the functional urological condition by means of a voiding diary. The treatment consisted of 10 weekly sessions of TPTNS lasting 30minutes. Some 57.7% of the patients showed abnormal tibial SEPs, and 42% showed abnormal pudendal SEPs. A statistically significant symptomatic improvement was observed in all clinical parameters after treatment with TPTNS, and 66% of the patients showed an overall improvement, regardless of sex, the presence of underlying neurological disorders, detrusor hyperactivity in the urodynamic study or SEP disorders. There were no adverse effects during the treatment. TPTNS is an effective and well tolerated treatment in patients with urge incontinence refractory to first-line therapies and should be offered early in the treatment strategy. New studies are needed to identify the optimal parameters of stimulation, the most effective treatment protocols and long-term efficacy, as well as its applicability to patients with a neurogenic substrate. Copyright © 2017 AEU. Publicado por Elsevier España, S.L.U. All rights reserved.

  13. Evaluation and Repair of War-Damaged Port Facilities. Report 3. Concepts for Expedient War-Damage Repair of Pier and Wharf Decking

    Science.gov (United States)

    1987-06-01

    td I CM e «) I <!• I O IS to SB 00 u 0...lööw^^^^^^WC^^I«^,^^^^ rr a-. iT. •’_ ^, rL ••_ »^^ ^’_ ■■_ iT^ . TD $ ii O H m oc so v/ O x O & L < •< 7 li . CM ^ §Q ^ x Z t...INNOVATION SESSION EXPEDIENT PORT REPAIR NAVAL CIVIL ENGINEERING LABORATORY 25 June 1985 ATTENDEES: Duane Davis, NAVCIVENGRLAB L53 Cliff

  14. Viewing alcohol warning advertising reduces urges to drink in young adults: an online experiment

    OpenAIRE

    Stautz, Kaidy; Marteau, Theresa M

    2016-01-01

    Abstract Background Tobacco counter-advertising is effective at promoting smoking cessation. Few studies have evaluated the impact of alcohol warning advertising on alcohol consumption and possible mechanisms of effect. This pilot study aimed to assess whether alcohol warning advertising is effective in reducing urges to drink alcohol, if emotional responses to advertising explain any such effect or perceived effectiveness, and whether e...

  15. The Role of Negative Affect and Self-Concept Clarity in Predicting Self-Injurious Urges in Borderline Personality Disorder Using Ecological Momentary Assessment.

    Science.gov (United States)

    Scala, J Wesley; Levy, Kenneth N; Johnson, Benjamin N; Kivity, Yogev; Ellison, William D; Pincus, Aaron L; Wilson, Stephen J; Newman, Michelle G

    2018-01-01

    Deficits in identity as well as negative affect have been shown to predict self-injurious and suicidal behaviors in individuals with borderline personality disorder (BPD). However, less is known about the interactive effects of these two predictors. We examined the moderating effect of a particular component of identity, self-concept, on the relationship between negative affect and self-injurious urges utilizing ecological momentary assessments. Outpatients diagnosed with either BPD (n = 36) or any anxiety disorder but no BPD (n = 18) completed surveys throughout the day over a 21-day period. Higher levels of momentary negative affect predicted greater subsequent urges to self-injure, but only when self-concept clarity was low (z = -3.60, p < .01). This effect did not differ between diagnostic groups. The results suggest that self-concept clarity has a protective effect against self-injurious urges in light of high negative affect, and that this effect may be transdiagnostic.

  16. LaURGE: Louisiana Undergraduate Recruitment and Geoscience Education

    Science.gov (United States)

    Nunn, J. A.; Agnew, J.

    2009-12-01

    NSF and the Shell Foundation sponsor a program called Louisiana Undergraduate Recruitment and Geoscience Education (LaURGE). Goals of LaURGE are: 1) Interweave geoscience education into the existing curriculum; 2) Provide teachers with lesson plans that promote interest in geoscience, critical thinking by students, and are consistent with current knowledge in geoscience; and 3) Provide teachers with supplies that make these lessons the highlights of the course. Biology workshops were held at LSU in Baton Rouge and Centenary College in Shreveport in July 2009. 25 teachers including 5 African-Americans attended the workshops. Teachers were from public and private schools in seven different parishes. Teacher experience ranged from 3 years to 40 years. Courses impacted are Biology, Honors Biology, AP Biology, and Environmental Science. The workshops began with a field trip to Mississippi to collect fossil shark teeth and create a virtual field trip. After the field trip, teachers do a series of activities on fossil shark teeth to illustrate evolution and introduce basic concepts such as geologic time, superposition, and faunal succession. Teachers were also given a $200 budget from which to select fossils for use in their classrooms. One of our exercises explores the evolution of the megatoothed shark lineage leading to Carcharocles megalodon, the largest predatory shark in history with teeth up to 17 cm long. Megatoothed shark teeth have an excellent fossil record and show continuous transitions in morphology from the Eocene to Pliocene. We take advantage of the curiosity of sharks shared by most people, and allow teachers to explore the variations among different shark teeth and to explain the causes of those variations. Objectives are to have teachers (and their students): 1) sort fossil shark teeth into biologically reasonable species; 2) form hypotheses about evolutionary relationships; and 3) describe and interpret evolutionary trends in the fossil Megatoothed

  17. Democracy and responsibility - a tangential concept for some

    International Nuclear Information System (INIS)

    Grimston, M.C.

    1995-01-01

    The Energy Issues Adviser for the British Nuclear Industry Forum provides a critical analysis of the work of anti-nuclear campaigners such as Friends of the Earth and Greenpeace. Stemming from the recent Channel Islands International Conference on Nuclear Waste, hosted by Guernsey Friends of the Earth, he argues that the anti-nuclear lobby use unscientific and emotive propaganda to influence political decisions. He urges a return to scientific and proven facts as the basis for policy decisions on nuclear waste and other waste issues, rather than political expediency. (UK)

  18. Substantiating the Expediency of Costs on Introduction of the System of Economic Security of Enterprise

    Directory of Open Access Journals (Sweden)

    Melikhova Tetiana O.

    2018-01-01

    Full Text Available The article substantiates expediency of introduction of the system of economic security of enterprise on the basis of money flows. The methods proposed in the long-term period stipulate the use as sources of financing: accumulated conditional economic costs, accumulated conditional gross and net money flow; and as costs: cumulative advanced costs and the advanced value of fixed assets. The article suggests methods for calculation of: gross index of conditional yield; gross conditional income of project; gross conditional profitability; gross conditional profitability of money flow. The managerial decision on introduction of the system of economic security of enterprise in the short-term production period has been substantiated on the basis of calculations of the following indicators: gross profitability of annual depreciation; annual gross economic effect; index of conditional yield of the gross money flow; differences between the conditional gross cash flow and the depreciation deductions associated with the implementation of the enterprise’s economic security system.

  19. Inhibitory effect of cervical trachea and chest wall vibrations on cough reflex sensitivity and perception of urge-to-cough in healthy male never-smokers

    OpenAIRE

    Kashiwazaki, Naohiro; Ebihara, Satoru; Gui, Peijun; Katayama, Norihiro; Ito, Kumiko; Sato, Ryuhei; Oyama, Chika; Ebihara, Takae; Kohzuki, Masahiro

    2013-01-01

    Background Non-pharmacological options for symptomatic management of cough are desired. Although chest wall mechanical vibration is known to ameliorate cough reflex sensitivity, the effect of mechanical vibrations on perceptions of urge-to-cough has not been studied. Therefore, we investigated the effect of mechanical vibration of cervical trachea, chest wall and femoral muscle on cough reflex sensitivity, perceptions of urge-to-cough as well as dyspnea. Methods Twenty-four healthy male never...

  20. Expedient synthesis of C-aryl carbohydrates by consecutive biocatalytic benzoin and aldol reactions.

    Science.gov (United States)

    Hernández, Karel; Parella, Teodor; Joglar, Jesús; Bujons, Jordi; Pohl, Martina; Clapés, Pere

    2015-02-16

    The introduction of aromatic residues connected by a C-C bond into the non-reducing end of carbohydrates is highly significant for the development of innovative structures with improved binding affinity and selectivity (e.g., C-aril-sLex). In this work, an expedient asymmetric "de novo" synthetic route to new aryl carbohydrate derivatives based on two sequential stereoselectively biocatalytic carboligation reactions is presented. First, the benzoin reaction of aromatic aldehydes to dimethoxyacetaldehyde is conducted, catalyzed by benzaldehyde lyase from Pseudomonas fluorescens biovar I. Then, the α-hydroxyketones formed are reduced by using NaBH4 yielding the anti diol. After acetal hydrolysis, the aldol addition of dihydroxyacetone, hydroxyacetone, or glycolaldehyde catalyzed by the stereocomplementary D-fructose-6-phosphate aldolase and L-rhamnulose-1-phosphate aldolase is performed. Both aldolases accept unphosphorylated donor substrates, avoiding the need of handling the phosphate group that the dihydroxyacetone phosphate-dependent aldolases require. In this way, 6-C-aryl-L-sorbose, 6-C-aryl-L-fructose, 6-C-aryl-L-tagatose, and 5-C-aryl-L-xylose derivatives are prepared by using this methodology. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Expedient data mining for nontargeted high-resolution LC-MS profiles of biological samples.

    Science.gov (United States)

    Hnatyshyn, Serhiy; Shipkova, Petia; Sanders, Mark

    2013-05-01

    The application of high-resolution LC-MS metabolomics for drug candidate toxicity screening reflects phenotypic changes of an organism caused by induced chemical interferences. Its success depends not only on the ability to translate the acquired analytical information into biological knowledge, but also on the timely delivery of the results to aid the decision making process in drug discovery and development. Recent improvements in analytical instrumentation have resulted in the ability to acquire extremely information-rich datasets. These new data collection abilities have shifted the bottleneck in the timeline of metabolomic studies to the data analysis step. This paper describes our approach to expedient data analysis of nontargeted high-resolution LC-MS profiles of biological samples. The workflow is illustrated with the example of metabolomics study of time-dependent fasting in male rats. The results from measurement of 220 endogenous metabolites in urine samples illustrate significant biochemical changes induced by fasting. The developed software enables the reporting of relative quantities of annotated components while maintaining practical turnaround times. Each component annotation in the report is validated using both calculated isotopic peaks patterns and experimentally determined retention time data on standards.

  2. Relationship between voided volume and the urge to void among patients with lower urinary tract symptoms.

    Science.gov (United States)

    Blaivas, Jerry G; Tsui, Johnson F; Amirian, Michael; Ranasinghe, Buddima; Weiss, Jeffrey P; Haukka, Jari; Tikkinen, Kari A O

    2014-12-01

    The aim of this study was to explore the relationship between voided volume (VV) and urge to void among patients with lower urinary tract symptoms. Consecutive adult patients (aged 23-90 years) were enrolled, and completed a 24 h bladder diary and the Urgency Perception Scale (UPS). Patients were categorized as urgency or non-urgency based on the Overactive Bladder Symptom Score. The relationship between UPS and VV (based on the bladder diary) was analyzed by Spearman's rho and proportional odds model. In total, 1265 micturitions were evaluated in 117 individuals (41 men, 76 women; 56 individuals in the urgency and 61 in the non-urgency group). The mean (± SD) VV and UPS were 192 ± 127 ml and 2.4 ± 1.2 ml in the urgency group and 173 ± 124 ml and 1.7 ± 1.1 ml in the non-urgency group, respectively. Spearman's rho (between UPS and VV) was 0.21 [95% confidence interval (CI) 0.13-029, p < 0.001] for the urgency group, 0.32 (95% CI 0.25-0.39, p < 0.001) for the non-urgency group, and 0.28 (95% CI 0.23-0.33, p < 0.001) for the total cohort. Urgency patients had higher UPS [odds ratio (OR) 3.1, 95% CI 2.5-3.8]. Overall, each additional 50 ml VV increased the odds of having a higher UPS with OR 1.2 (95% CI 1.2-1.3). The relationship between VV and UPS score was similar in both groups (p = 0.548 for interaction). Although urgency patients void with a higher UPS score, among both urgency and non-urgency patients there is only a weak correlation between VV and the urge to void. This suggests that there are factors other than VV that cause the urge to void.

  3. Colon manometry proves that perception of the urge to defecate is present in children with functional constipation who deny sensation.

    Science.gov (United States)

    Firestone Baum, Carrie; John, Anub; Srinivasan, Kavitha; Harrison, Prince; Kolomensky, Andrew; Monagas, Javier; Cocjin, Jose; Hyman, Paul E

    2013-01-01

    Children with functional constipation often state an inability to sense an urge to defecate and/or inability to feel incontinence. We used colon manometry to assess whether there was a sensory abnormality in patients who denied sensation. A physician observed all of the colon manometries in the preceding 20 years, and included behavioral observations in the procedure reports. We reviewed the charts of these patients. Of 150 subjects with normal manometry and a diagnosis of functional constipation, 56 volunteered that they had no urge to defecate or complained of abdominal pain. For all who denied sensation, the first high-amplitude propagating colonic contraction (HAPC) was associated with retentive posturing and facial grimaces. When queried, all reported they felt nothing. The examiner explained the HAPC was causing pain, and informed the child that the pain would resolve if they defecated. With subsequent HAPCs, every patient acknowledged an urge to defecate and successfully defecated. Most agreed that a similar pain sensation was present daily, but was misinterpreted to be abdominal pain. Colon manometry may be useful not only for objective findings to discriminate neuromuscular disease from functional symptoms but also to understand psychological issues and aid in helping the child and family understand the maladaptive behaviors in functional constipation.

  4. ADVOCACY OF PHARMACIST TOWARDS CONCOMITANT SOCIAL MEDIA: MEETING AN URGE TO PATIENTS NEED & OUTCOME

    OpenAIRE

    Ravi Pratap Pulla* & Veena Rani Inugala

    2017-01-01

    In the modern era, technology has taken a radical avant-garde towards social media. It is presently being used as a stature household need by every mankind. The revolutionary of social media has brought a dynamic impact in networking health information between the professional and patient, irrespective of age group. This laid a “bleeding-heart” platform for pharmacist, escalating the utilization by improving the health outcomes and meeting the urge. There is a vague informative literature aro...

  5. A response to: "NIST experts urge caution in use of courtroom evidence presentation method"

    OpenAIRE

    Morrison, Geoffrey Stewart

    2017-01-01

    A press release from the National Institute of Standards and Technology (NIST)could potentially impede progress toward improving the analysis of forensic evidence and the presentation of forensic analysis results in courts in the United States and around the world. "NIST experts urge caution in use of courtroom evidence presentation method" was released on October 12, 2017, and was picked up by the phys.org news service. It argues that, except in exceptional cases, the results of forensic ana...

  6. The brain activations for both cue-induced gaming urge and smoking craving among subjects comorbid with Internet gaming addiction and nicotine dependence.

    Science.gov (United States)

    Ko, Chih-Hung; Liu, Gin-Chung; Yen, Ju-Yu; Yen, Cheng-Fang; Chen, Cheng-Sheng; Lin, Wei-Chen

    2013-04-01

    Internet gaming addiction (IGA) has been classified as an addictive disorder in the proposed DSM 5 draft. However, whether its underlying addiction mechanism is similar to other substance use disorders has not been confirmed. The present functional magnetic resonance images study is aimed at evaluating the brain correlates of cue-induced gaming urge or smoking craving in subjects with both IGA and nicotine dependence to make a simultaneous comparison of cue induced brain reactivity for gaming and smoking. For this purpose, 16 subjects with both IGA and nicotine dependence (comorbid group) and 16 controls were recruited from the community. All subjects were made to undergo 3-T fMRIs scans while viewing images associated with online games, smoking, and neutral images, which were arranged according to an event-related design. The resultant image data was analyzed with full factorial and conjunction analysis of SPM5. The results demonstrate that anterior cingulate, and parahippocampus activates higher for both cue-induced gaming urge and smoking craving among the comorbid group in comparison to the control group. The conjunction analysis demonstrates that bilateral parahippocampal gyrus activates to a greater degree for both gaming urge and smoking craving among the comorbid group in comparison to the control group. Accordingly, the study demonstrates that both IGA and nicotine dependence share similar mechanisms of cue-induced reactivity over the fronto-limbic network, particularly for the parahippocampus. The results support that the context representation provided by the parahippocampus is a key mechanism for not only cue-induced smoking craving, but also for cue-induced gaming urge. Copyright © 2012 Elsevier Ltd. All rights reserved.

  7. Live-cell topology assessment of URG7, MRP6102 and SP-C using glycosylatable green fluorescent protein in mammalian cells

    International Nuclear Information System (INIS)

    Lee, Hunsang; Lara, Patricia; Ostuni, Angela; Presto, Jenny; Johansson, Janne; Nilsson, IngMarie; Kim, Hyun

    2014-01-01

    Highlights: • Glycosylatable GFP (gGFP) is developed for the use in mammalian cells. • gGFP selectively loses its fluorescence upon N-linked glycosylation in the ER lumen. • Differential fluorescence/glycosylation pattern probes membrane protein topology. • Membrane topology of URG7, MRP6 102 , and SP-C was determined by gGFP tagging in vivo. - Abstract: Experimental tools to determine membrane topology of a protein are rather limited in higher eukaryotic organisms. Here, we report the use of glycosylatable GFP (gGFP) as a sensitive and versatile membrane topology reporter in mammalian cells. gGFP selectively loses its fluorescence upon N-linked glycosylation in the ER lumen. Thus, positive fluorescence signal assigns location of gGFP to the cytosol whereas no fluorescence signal and a glycosylated status of gGFP map the location of gGFP to the ER lumen. By using mammalian gGFP, the membrane topology of disease-associated membrane proteins, URG7, MRP6 102 , SP-C(Val) and SP-C(Leu) was confirmed. URG7 is partially targeted to the ER, and inserted in C in form. MRP6 102 and SP-C(Leu/Val) are inserted into the membrane in C out form. A minor population of untargeted SP-C is removed by proteasome dependent quality control system

  8. Perception of urge-to-cough and dyspnea in healthy smokers with decreased cough reflex sensitivity

    OpenAIRE

    Kanezaki, Masashi; Ebihara, Satoru; Nikkuni, Etsuhiro; Gui, Peijun; Suda, Chihiro; Ebihara, Takae; Yamasaki, Miyako; Kohzuki, Masahiro

    2010-01-01

    Background Although cigarette smoking has been implicated as an important risk factor for the development of respiratory symptoms, the perceptional aspects of two symptoms in smokers have not been fully elucidated. Therefore, we simultaneously evaluated the cough reflex sensitivity, the cognition of urge-to-cough and perception of dyspnea in both healthy smokers and non-smokers. Methods Fourteen male healthy never-smokers and 14 age-matched male healthy current-smokers were recruited via publ...

  9. Migratory urge and gll Na+,K+-ATPase activity of hatchery-reared Atlantic salmon smolts from the Dennys and Penobscot River stocks, Maine

    Science.gov (United States)

    Spencer, Randall C.; Zydlewski, Joseph D.; Zydlewski, Gayle B.

    2010-01-01

    Hatchery-reared Atlantic salmon Salmo salar smolts produced from captive-reared Dennys River and sea-run Penobscot River broodstock are released into their source rivers in Maine. The adult return rate of Dennys smolts is comparatively low, and disparity in smolt quality between stocks resulting from genetic or broodstock rearing effects is plausible. Smolt behavior and physiology were assessed during sequential 14-d trials conducted in seminatural annular tanks with circular flow. “Migratory urge” (downstream movement) was monitored remotely using passive integrated transponder tags, and gill Na+,K+-ATPase activity was measured at the beginning and end of the trials to provide an index of smolt development. The migratory urge of both stocks was low in early April, increased 20-fold through late May, and declined by the end of June. The frequency and seasonal distribution of downstream movement were independent of stock. In March and April, initial gill Na+,K+-ATPase activities of Penobscot River smolts were lower than those of Dennys River smolts. For these trials, however, Penobscot River smolts increased enzyme activity after exposure to the tank, whereas Dennys River smolts did not, resulting in similar activities between stocks at the end of all trials. There was no clear relationship between migratory urge and gill Na+,K+-ATPase activity. Gill Na+,K+-ATPase activity of both stocks increased in advance of migratory urge and then declined while migratory urge was increasing. Maximum movement was observed from 2 h after sunset through 1 h after sunrise but varied seasonally. Dennys River smolts were slightly more nocturnal than Penobscot River smolts. These data suggest that Dennys and Penobscot River stocks are not markedly different in either physiological or behavioral expression of smolting.

  10. Serum estradiol does not differentiate stress, mixed and urge incontinent women around menopause. A report from the Women's Health in the Lund Area (WHILA) study.

    Science.gov (United States)

    Hamer, Maria Andrada; Källén, Karin; Lidfeldt, Jonas; Samsioe, Göran; Teleman, Pia

    2011-11-01

    To outline serum estradiol levels in perimenopausal women with stress, mixed or urge incontinence. We believe the majority of urgency symptoms in perimenopausal women to be caused by a pelvic floor dysfunction and a hypermobility of the bladder neck. If this is the case, there would be no difference in estradiol levels between the groups. University hospital. In the observational Women's Health in the Lund Area study, a subset of 400/2221 women reporting urinary incontinence completed a detailed questionnaire regarding lower urinary tract symptoms and had their serum steroid hormone levels measured. Statistical analyses were made by Chi-square test, nonparametrical tests, ANOVA, multi- and univariate logistic regression analysis. Stress incontinence was reported by 196, mixed incontinence by 153 and urge incontinence by 43 women; in 369, serumestradiol values were available. Serum estradiol did not differ significantly between stress incontinent (median 49.5 pmo/l, range 2.63-875.4), urge incontinent (median 31.6 pmol/l, range 2.63-460.7) or mixed incontinent women (median 35.5 pmol/l, range 2.63-787.9, p=0.62). Logistic regression analysis correcting for age, parity, hormonal status, smoking, hysterectomy and BMI also failed to show any difference in estradiol levels between the groups (p=0.41-0.58). No significant differences in serum estradiol levels between stress, mixed or urge incontinent perimenopausal women could be demonstrated. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  11. Establishing motives for committing crimes: criminalistic possibilities and criminal procedure expediency

    Directory of Open Access Journals (Sweden)

    Kornakova S.V.

    2014-12-01

    Full Text Available The lack of unanimity on the motive understanding by psychologists studying the motivation of goal-oriented behavior and lawyers analyzing the crime causes and mechanisms is stated. The possibility of unconscious motives of criminal behavior is admitted. The practical problems of es-tablishing and proving the motives for specific crimes, which can be judged only presumably, by studying actus reus and perpetrator’s testimony, are shown. Establishing the motive for crime is complicated by the fact that the guilty person is often not aware of it, conceals or distorts it. The authors acknowledge that crime is impossible without a motive (talking about mentally healthy person. Consequently, they state the inevitable difficulties in establishing any motive and the lack of objective need for its establishing to find a person guilty of committing a crime. The expediency of establishing cognition limits of crime psychology by the subject of proof is argued. It’s concluded that the preliminary investigation bodies and courts must fully, comprehensively and objectively investigate the circumstances that determine the conclusion about the presence or absence of guilty motive in perpetrator’s actions. They must justify this conclusion in the indictment and sentence by bringing evidence only in case if this motive is provided by criminal law as element of crime. It’s argued that the list of circumstances to be proved in every criminal case, provided by article 73 of the RF Criminal Procedure Code, can’t be considered satisfactory, if practical possibilities of their establishing aren’t taken into account. It’s proposed to exclude the motives for crime from this list.

  12. Junk food advertising moderates the indirect effect of reward sensitivity and food consumption via the urge to eat.

    Science.gov (United States)

    Kidd, Chloe; Loxton, Natalie J

    2018-05-01

    The current study aimed to identify how underlying individual differences increases vulnerability to television food advertising. In particular, this study examined how reward sensitivity, a biologically-based predisposition to approach rewards (such as appetitive foods) in the environment, influenced participants' vulnerability to television food advertising and subsequent food consumption. Ninety-eight participants were randomly assigned to a cue condition (food cues versus non-food cues) and then viewed a 30 min documentary interrupted by advertising featuring a mix of food and neutral advertising (food cue condition) or only neutral advertising (non-food cue condition). Participants' reward sensitivity, approach motivation measured as urge to eat, and food consumption were recorded. Moderated mediation regression analyses revealed the positive association between reward sensitivity and food consumption was mediated by an increase in urge to eat, but only when participants were exposed to food advertising. These findings suggest heightened reward sensitivity, exposure to appetitive food cues, and approach motivation are key interacting mechanisms that may lead to maladaptive eating behaviours. Copyright © 2018 Elsevier Inc. All rights reserved.

  13. Movie Smoking, Movie Horror, and Urge to Smoke

    Science.gov (United States)

    SARGENT, James D.; MARUSKA, Karin; MORGENSTERN, Matthis; ISENSEE, Barbara; HANEWINKEL, Reiner

    2010-01-01

    It is known that exposure to smoking cues increases urge to smoke (UTS), but little is known about other media factors that might also increase UTS. We hypothesized that horror/thriller movies might also increase UTS by increasing negative affect. We surveyed 536 movie patrons who were smokers aged 18 years or older. Subjects had exited 26 movies, of which 12 contained smoking and two were horror films, one with and one without smoking. We used random effects regression to assess the association between exposure to movie smoking, movie horror, both and UTS, controlling for confounding factors. Median age was 26 years and 52% were female. Mean UTS was 5.9, 6.6, 6.6, and 8.7 for smokers exiting movies without smoking, with smoking, horror without smoking and horror with smoking respectively. Smoking in movies was associated with a significantly higher UTS (0.63 [95% CI 0.31–0.94]). Horror with smoking increased UTS by 2.8 points (95% C.I. 2.3, 3.5); the horror without smoking estimate was 0.88, but not statistically significant. This short report offers preliminary evidence that movie horror as one factor besides visual smoking cues that could increase UTS in a community setting. PMID:20301876

  14. Live-cell topology assessment of URG7, MRP6{sub 102} and SP-C using glycosylatable green fluorescent protein in mammalian cells

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Hunsang [School of Biological Sciences, Seoul National University, Seoul 151-747 (Korea, Republic of); Lara, Patricia [Center for Biomembrane Research, Department of Biochemistry and Biophysics, Stockholm University, SE-106 91 Stockholm (Sweden); Ostuni, Angela [Department of Sciences, University of Basilicata, Viale dell’Ateneo Lucano 10, 85100 Potenza (Italy); Presto, Jenny [Karolinska Institutet, Dept of Neurobiology, Care Sciences and Society, Novum 5th Floor, 141 86 Stockholm (Sweden); Johansson, Janne [Karolinska Institutet, Dept of Neurobiology, Care Sciences and Society, Novum 5th Floor, 141 86 Stockholm (Sweden); Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, The Biomedical Centre, 751 23 Uppsala (Sweden); Institute of Mathematics and Natural Sciences, Tallinn University, Narva mnt 25, 101 20 Tallinn (Estonia); Nilsson, IngMarie [Center for Biomembrane Research, Department of Biochemistry and Biophysics, Stockholm University, SE-106 91 Stockholm (Sweden); Kim, Hyun, E-mail: joy@snu.ac.kr [School of Biological Sciences, Seoul National University, Seoul 151-747 (Korea, Republic of)

    2014-08-08

    Highlights: • Glycosylatable GFP (gGFP) is developed for the use in mammalian cells. • gGFP selectively loses its fluorescence upon N-linked glycosylation in the ER lumen. • Differential fluorescence/glycosylation pattern probes membrane protein topology. • Membrane topology of URG7, MRP6{sub 102}, and SP-C was determined by gGFP tagging in vivo. - Abstract: Experimental tools to determine membrane topology of a protein are rather limited in higher eukaryotic organisms. Here, we report the use of glycosylatable GFP (gGFP) as a sensitive and versatile membrane topology reporter in mammalian cells. gGFP selectively loses its fluorescence upon N-linked glycosylation in the ER lumen. Thus, positive fluorescence signal assigns location of gGFP to the cytosol whereas no fluorescence signal and a glycosylated status of gGFP map the location of gGFP to the ER lumen. By using mammalian gGFP, the membrane topology of disease-associated membrane proteins, URG7, MRP6{sub 102}, SP-C(Val) and SP-C(Leu) was confirmed. URG7 is partially targeted to the ER, and inserted in C{sub in} form. MRP6{sub 102} and SP-C(Leu/Val) are inserted into the membrane in C{sub out} form. A minor population of untargeted SP-C is removed by proteasome dependent quality control system.

  15. India Prime Minister urges more awareness to control HIV.

    Science.gov (United States)

    1999-01-04

    With an estimated 3-4 million people infected with HIV, of whom half are aged 18-40 years, India should consider its HIV/AIDS epidemic as a national problem and address it accordingly. The disease also needs to be treated as a societal issue which affects the productivity of both economic and social sectors. The control of HIV and AIDS figures prominently in a new health policy currently being developed. At a seminar on AIDS, Prime Minister of India Atal Behari Vajpayee asked industry to supplement the government's efforts to spread awareness about AIDS. He stressed that business and industry need to seriously acknowledge the reality of HIV/AIDS and act to increase awareness about AIDS by spreading the message about prevention. Awareness is the key to prevention. Millions of HIV-positive people in India are afraid to seek medical care because of undue guilt and stigmatization. Also, young people should be taught about healthy sexual behavior and its implications. Vajpayee urged the minister of health to explore the possibilities of urgently developing an indigenous vaccine for AIDS in the most cost-effective manner.

  16. Validação da versão brasileira do Questionnaire of Smoking Urges-Brief

    OpenAIRE

    Araujo,Renata Brasil; Oliveira,Margareth da Silva; Moraes,João Feliz Duarte; Pedroso,Rosemeri Siqueira; Port,Franciny; Castro,Maria da Graça Tanori de

    2007-01-01

    CONTEXTO: A avaliação do craving (ou fissura) é muito importante no tratamento do tabagismo. OBJETIVO: O objetivo desta pesquisa foi validar a versão brasileira do Questionnaire of Smoking Urges-Brief (QSU-B). MÉTODOS: O delineamento foi experimental, e seus participantes foram divididos, aleatoriamente, em grupos de zero, 30 e 60 minutos de abstinência do tabaco. A amostra foi de 201 sujeitos (134 mulheres e 67 homens), entre 18 e 65 anos (M = 38,15), e os instrumentos aplicados, além do QSU...

  17. Premonitory Urge for Tics Scale (PUTS): replication and extension of psychometric properties in youth with chronic tic disorders (CTDs).

    Science.gov (United States)

    Raines, Jeremy M; Edwards, Kimberly R; Sherman, Martin F; Higginson, Christopher I; Winnick, Joel B; Navin, Kelly; Gettings, Julie M; Conteh, Fatmata; Bennett, Shannon M; Specht, Matthew W

    2018-04-01

    Individuals with chronic tic disorders (CTDs) frequently describe aversive subjective sensory sensations that precede their tics. The first aim of the present study was to explore the psychometric properties of a standardized self-report measure to assess premonitory urges in CTDs, The Premonitory Urge for Tics Scale (PUTS), by replicating the analyses of Woods et al. (J Dev Behav Pediatr 26:397-403, 2005) using a sample twice the size of theirs. The second aim was to conduct an exploratory factor analysis of the PUTS. Eighty-four youth with CTDs, recruited from a pediatric OCD and tic specialty clinic, completed the PUTS while their caregivers completed The Parent Tic Questionnaire (PTQ) and a demographic measure. Consistent with (Woods et al. J Dev Behav Pediatr 26:397-403, 2005), the PUTS was found to be internally consistent (α = 0.82) and significantly correlated with overall tic severity as measured by the PTQ (r = 0.24, p tics than the frequency or intensity of tics.

  18. Expedient Protocols for the Installation of Pyrimidine Based Privileged Templates on 2-Position of Pyrrolo[2,1-c][1,4]-benzodiazepine Nucleus Linked Through a p-phenoxyl Spacer

    Directory of Open Access Journals (Sweden)

    Anshu Agarwal

    2012-01-01

    Full Text Available Exceedingly facile single step expedient protocols based on the versatility and reactivity of corresponding intermediates : [2-(dimethylaminomethylene ketone] (5 and chalcone (6, derived from 2-(p-acetyl phenoxyl substituted analogue of pyrrolo[2,1-c][1,4]-benzodiazepine (4, have been developed to provide an easy installation of the pyrimidine based privileged templates at 2-position of pyrrolo[2,1-c][1,4]-benzodiazepine through a p-phenoxyl spacer, by utilizing the synthetic strategy depicted in schemes-1 and 2.

  19. Validação da versão brasileira do Questionnaire of Smoking Urges-Brief Validation of the Brazilian version of Questionnaire of Smoking Urges-Brief

    Directory of Open Access Journals (Sweden)

    Renata Brasil Araujo

    2007-01-01

    Full Text Available CONTEXTO: A avaliação do craving (ou fissura é muito importante no tratamento do tabagismo. OBJETIVO: O objetivo desta pesquisa foi validar a versão brasileira do Questionnaire of Smoking Urges-Brief (QSU-B. MÉTODOS: O delineamento foi experimental, e seus participantes foram divididos, aleatoriamente, em grupos de zero, 30 e 60 minutos de abstinência do tabaco. A amostra foi de 201 sujeitos (134 mulheres e 67 homens, entre 18 e 65 anos (M = 38,15, e os instrumentos aplicados, além do QSU-B, foram: Ficha com Dados Sociodemográficos, Escala Analógico-Visual do Craving, Fagerström Test for Nicotine Dependence e Inventários Beck de Ansiedade e de Depressão. RESULTADOS: A análise fatorial com dois fatores teve variância total de 78,46% e a correlação entre esses fatores foi significativa e de alta intensidade (r = 0,636; p BACKGROUND: The evaluation of craving is very important to treatment of tobacco dependence. OBJECTIVE:The objective of this research was to validate the Brazilian version of the Questionnaire of Smoking Urges-Brief (QSU-B. METHOD: Subjects enrolled to this experimental study were randomized into groups of zero, 30 and 60 minutes of tobacco abstinence. The study group was composed by 201 subjects (134 females and 67 males, age range: 18 to 65 (M = 38.15. The assessment instruments were, in addition to the QSU-B: Social and Demographical Data Form, Visual Analogic Scale for Craving, Fagerström Test for Nicotine Dependence and Anxiety and Depression Beck Inventories. RESULTS: The two-factor factorial analysis presented a total variation of 78.46% and the correlation between these factors was significant and of high intensity (r = 0.636; p < 0.001. All Cronbach’s alpha values from QSU-B were above 0.70. We observed a correlation between the QSU-B total score and the Visual Analogic Scale (r = 0.656; p < 0.001, and also with Fagerström’s question 1 (r = 0.201; p = 0.004 and question 2 (r = 0.257; p < 0

  20. Colleges Urged to Instill "Charitable Impulse" in Students, Inspire Them to Reorient Public Policy as Well as Donate Their Time and Money.

    Science.gov (United States)

    McMillen, Liz

    1987-01-01

    The president of the Council on Foundations, James A. Joseph, urges educators to develop volunteers who can eliminate the causes of social problems. Colleges and universities are in a special position to instill a sense of social responsibility in students. (MLW)

  1. Tempo resposta de um serviço de atendimento móvel de urgência

    OpenAIRE

    Rosane Mortari Ciconet

    2015-01-01

    O tempo resposta é um indicador usado para avaliação da qualidade de serviços de atendimento pré-hospitalar (APH). Consiste no intervalo de tempo entre a expressão do pedido de socorro até a chegada da equipe à cena do evento. Assim, o objetivo do estudo foi analisar o tempo resposta de um SAMU, referente aos chamados para atendimentos clínicos e traumáticos demandados à Central de Regulação de Urgências. Os agravos clínicos foram compostos pelas síndromes neurológicas, cardiovasculares e res...

  2. Effects of suppression and acceptance of sadness on the urge for non-suicidal self-injury and self-punishment.

    Science.gov (United States)

    Svaldi, Jennifer; Dorn, Christina; Matthies, Swantje; Philipsen, Alexandra

    2012-12-30

    The present study wanted to test the course of the urge for non-suicidal self-injury (UNSSI) and the urge for self-punishment (USP) when suppressing or accepting upcoming emotions in response to a sadness-inducing film clip in female participants with borderline personality disorder (BPD). Thirty-six women with BPD were allocated either to a condition in which they were asked to engage in expressive suppression or acceptance while watching a sadness-inducing film clip. Ratings of UNSSI, USP, and positive and negative emotions were assessed prior to the clip (baseline), immediately after it (t1) and after a 5min waiting period (t2), during which participants viewed landscape pictures. Additionally, physiological measures were obtained. Main results revealed a significant increase in UNSSI from baseline to t2 in the acceptance, but not in the suppression group. Furthermore, USP scores significantly increased from baseline to t2 in the acceptance, but not in the suppression condition. However, there was no differential impact on the sympathetic and parasympathetic branch depending on strategy. The results are in line with recent literature showing that expressive suppression in BPD may also have an adaptive function. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  3. Expedições científicas, fotografia e intenção documentária: as viagens do Instituto Oswaldo Cruz (1911-1913 Scientific expeditions, photography, and documental intent: the Oswaldo Cruz Institute expeditions (1911-1913

    Directory of Open Access Journals (Sweden)

    Maria Teresa Villela Bandeira de Mello

    2009-07-01

    Full Text Available Analisa as séries fotográficas produzidas pelo Instituto Oswaldo Cruz em expedições científicas ao interior do Brasil, realizadas entre 1911 e 1913. Detém-se na expedição liderada por Arthur Neiva e Belisário Penna e na elaboração do seu discurso documentário. Explicita escolhas e ênfases adotadas na elaboração de cada texto visual, expresso tanto no material produzido durante o percurso quanto na seleção das imagens para publicação. As análises quantitativa e qualitativa das imagens da expedição de Neiva e Penna revelam um percurso narrativo que articula o meio natural, a vida social e as evidências de adoecimento das populações interioranas, para a constituição de um discurso que difunde o movimento pelo saneamento dos sertões.The article analyzes the photographic series produced by the Oswaldo Cruz Institute in reference to scientific expeditions into the interior of Brazil between 1911 and 1913, with a special focus on the one headed by Arthur Neiva and Belisário Penna and on the development of their documentary discourse. It draws out the choices and emphases used in preparing each visual text, expressed both in the material produced during the journeys and in the process of selecting images for publication. The study's quantitative and qualitative analyses of images from the Neiva-Penna expedition uncover a narrative journey that articulates the natural environment, social life, and evidence of the sickly status of residents of the interior to shape a discourse that disseminates the nascent movement to sanitize the sertão regions.

  4. A prática de exercícios físicos é um fator modificável da incontinência urinária de urgência em mulheres idosas The practice of physical exercise is a modifiable factor for urge urinary incontinence in older women

    Directory of Open Access Journals (Sweden)

    Janeisa Franck Virtuoso

    2013-04-01

    Full Text Available INTRODUÇÃO: A literatura aponta que alguns fatores de risco para incontinência urinária podem ser modificados por um estilo de vida saudável; no entanto, pouco se conhece sobre os fatores associados à incontinência urinária de urgência (IUU, cuja prevalência aumenta com a idade. OBJETIVO: Analisar os fatores de risco modificáveis da IUU em mulheres idosas. MÉTODOS: A amostra foi composta por 200 idosas (60 anos ou mais com média de idade de 69,06 ± 6,26 anos. Foram identificadas a presença de IUU e os fatores de risco comportamentais (consumo de café, consumo de bebidas alcoólicas, hábito de fumar e presença de constipação. Também foi aplicado o Domínio 4 do Questionário Internacional de Atividade Física (IPAQ para identificação do nível de atividade física e mensurados Índice de Massa Corporal e Circunferência da Cintura. Os dados foram tratados por meio de estatística descritiva e inferencial, com nível de significância de 5%. RESULTADOS: A prevalência de IUU na amostra foi de 15,5%. Entre os fatores modificáveis, apenas o nível de atividade física associou-se com a ocorrência de IUU, sendo que a prática de exercícios físicos apresentou-se como um fator de proteção entre mulheres muito ativas (OR = 0,288 e pouco ativas (OR = 0,356. CONCLUSÃO: Os sintomas de urgência miccional podem ser amenizados com a prática regular de exercícios físicos. Através de um estilo de vida saudável é possível minimizar uma série de fatores modificáveis na gênese da incontinência urinária de urgência.INTRODUCTION: The literature suggests that some risk factors for urinary incontinence can be modified by a healthy lifestyle; however, little is known about the factors associated with urge urinary incontinence (UUI, whose prevalence increases with age. OBJECTIVE: To examine the modifiable risk factors of UUI in older women. METHOD: The sample consisted of 200 elderly (60 years or older women with mean age of

  5. Riscos de acidentes com materiais perfurocortantes no setor de urgência de um hospital público Risks of accidents with needlestick materials at the urgency sector of a public hospital

    Directory of Open Access Journals (Sweden)

    Francisca Francineide Andrade da Silva

    2016-10-01

    Full Text Available Objetivo: Conhecer os fatores de risco relacionados aos acidentes com material perfurocortante presente no trabalho dos técnicos de enfermagem do setor de atendimento de urgência de um hospital público. Método:Trata-se de um estudo descritivo, de abordagem qualitativa realizado com 14 profissionais. Os dados foram obtidos por meio de entrevistas semi-estruturadas, no período de julho a setembro de 2010 e analisados seguindo a análise temática categorial. Resultados: As categorias emergidas dos discursos dos entrevistados foram: situações de urgências e emergências, adesão aos Equipamentos de Proteção Individual, Descuido e armazenamento inadequado do material perfurocortante. Conclusão: Observou-se que as condições de trabalho no setor de urgência necessitam ser revistas, a fim de oferecer um ambiente adequado para minimizar os riscos ocupacionais durante o desenvolvimento dos procedimentos de enfermagem. Descritores: Saúde do trabalhador, riscos ocupacionais, fatores de risco.

  6. A method for the production and expedient screening of CRISPR/Cas9-mediated non-transgenic mutant plants.

    Science.gov (United States)

    Chen, Longzheng; Li, Wei; Katin-Grazzini, Lorenzo; Ding, Jing; Gu, Xianbin; Li, Yanjun; Gu, Tingting; Wang, Ren; Lin, Xinchun; Deng, Ziniu; McAvoy, Richard J; Gmitter, Frederick G; Deng, Zhanao; Zhao, Yunde; Li, Yi

    2018-01-01

    Developing CRISPR/Cas9-mediated non-transgenic mutants in asexually propagated perennial crop plants is challenging but highly desirable. Here, we report a highly useful method using an Agrobacterium -mediated transient CRISPR/Cas9 gene expression system to create non-transgenic mutant plants without the need for sexual segregation. We have also developed a rapid, cost-effective, and high-throughput mutant screening protocol based on Illumina sequencing followed by high-resolution melting (HRM) analysis. Using tetraploid tobacco as a model species and the phytoene desaturase ( PDS ) gene as a target, we successfully created and expediently identified mutant plants, which were verified as tetra-allelic mutants. We produced pds mutant shoots at a rate of 47.5% from tobacco leaf explants, without the use of antibiotic selection. Among these pds plants, 17.2% were confirmed to be non-transgenic, for an overall non-transgenic mutation rate of 8.2%. Our method is reliable and effective in creating non-transgenic mutant plants without the need to segregate out transgenes through sexual reproduction. This method should be applicable to many economically important, heterozygous, perennial crop species that are more difficult to regenerate.

  7. A preliminary study of the neural correlates of the intensities of self-reported gambling urges and emotions in men with pathological gambling.

    Science.gov (United States)

    Balodis, Iris M; Lacadie, Cheryl M; Potenza, Marc N

    2012-09-01

    Although self-reported gambling urge intensities have clinical utility in the treatment of pathological gambling (PG), prior studies have not investigated their neural correlates. Functional magnetic resonance imaging (fMRI) was conducted while 10 men with PG and 11 control comparison (CON) men viewed videotaped scenarios of gambling, happy or sad content. Participants rated the intensity of their emotions and motivations and reported the qualities of their responses. Relative to the CON group, the PG group reported similar responses to sad and happy scenarios, but stronger emotional responses and gambling urges when viewing the gambling scenarios. Correlations between self-reported responses and brain activations were typically strongest during the period of reported onset of emotional/motivational response and more robust in PG than in CON subjects for all conditions. During this epoch, corresponding with conscious awareness of an emotional/motivational response, subjective ratings of gambling urges in the PG group were negatively correlated with medial prefrontal cortex activation and positively correlated with middle temporal gyrus and temporal pole activations. Sadness ratings in the PG group correlated positively with activation of the medial orbitofrontal cortex, middle temporal gyrus, and retrosplenial cortex, while self-reported happiness during the happy videos demonstrated largely inverse correlations with activations in the temporal poles. Brain areas identified in the PG subjects have been implicated in explicit, self-referential processing and episodic memory. The findings demonstrate different patterns of correlations between subjective measures of emotions and motivations in PG and CON subjects when viewing material of corresponding content, suggesting in PG alterations in the neural correlates underlying experiential aspects of affective processing.

  8. Úlceras em megacólons chagásicos operados na urgência e eletivamente Ulcerations in Chagas' megacolon operated at urgency and electively

    Directory of Open Access Journals (Sweden)

    Augusto Diogo-Filho

    2006-12-01

    Full Text Available RACIONAL: O megacólon é uma doença freqüente no nosso meio e abordado na urgência pelas suas complicações como fecalomas, volvos e perfurações. As úlceras de estases nos megacólons contribuem como prováveis sítios de perfurações OBJETIVO: Comparar as freqüências de úlceras de decúbito em megacólons chagásicos operados na urgência, por volvo e fecaloma, e eletivamente, objetivando melhor conduta cirúrgica na urgência MATERIAL E MÉTODOS: Analisaram-se os laudos de 356 exames anatomopatológicos de ressecções colônicas de pacientes operados por megacólon chagásico na urgência (102 casos; 29% e eletivamente (254 casos; 71%, no período de 1980 a 2000. As indicações cirúrgicas de urgência foram atribuídas a volvo (71 casos; 69,6%, fecaloma (25 casos; 24,5%, abdome agudo perfurativo após sondagem retal ou sigmoidoscopia (6 casos; 5,9%. Compararam-se as freqüências de úlceras nos dois grupos de peças cirúrgicas, com a utilização do teste do qui-quadrado RESULTADOS: Nos laudos das peças cirúrgicas obtidas nas cirurgias de urgência, constatou-se o registro de úlceras em 26 casos (25,5%; nas peças de ressecções eletivas verificaram-se úlceras em 21 casos (8,25%. A diferença observada foi estatisticamente significante. A comparação dos grupos de volvo, fecaloma e volvo com fecaloma, em separado com o grupo das cirurgias eletivas, evidenciou diferenças significantes em relação ao volvo e ao fecaloma CONCLUSÃO: A freqüência muito maior de úlceras nos megas operados em caráter de urgência enfatiza a necessidade da ressecção imediata do cólon sigmóide, ao invés da conduta conservadora de simples colostomia descompressiva, mesmo naquelas laparotomias exploradoras em que o exame macroscópico do sigmóide não mostre sinais de necrose. Desta forma, deve-se prevenir a ocorrência de perfuração do megacólon no pós-operatório mediato, com conseqüências usualmente graves.BACKGROUD: The

  9. Inserção de um hospital de grande porte na Rede de Urgências e Emergências da região Centro-Oeste

    Directory of Open Access Journals (Sweden)

    Emanuelly Paulino Soares

    Full Text Available Em face da exigência de se configurar as redes de cuidados, este estudo qualitativo analisa a inserção de um hospital de grande porte na Rede de Atenção às Urgências e Emergências na região Centro-Oeste do Brasil utilizando dados secundários, análise documental e entrevistas semiestruturadas aplicadas aos gestores e profissionais que atuam no Centro de Trauma. Os resultados sugerem desconhecimento dos profissionais quanto à inserção do Hospital na rede; definição de fluxos e pactos incipiente; boas práticas na regulação pelo Serviço de Atendimento Móvel de Urgências. Conclui-se que a inserção do Hospital acontece de forma lenta e depende da articulação dos vários níveis do Sistema Único de Saúde.

  10. Kirkilas appeals to patriotism of private energy firm

    Index Scriptorium Estoniae

    2007-01-01

    Leedu peaminister kutsub kolme Leedu energeetikaettevõtet ühinema ehitamaks uut tuumaelektrijaama. Valitsus pole rahul ühinevate ettevõtete varade hinnanguga, mille tegi audiitorfirma KPMG Baltics

  11. An Analysis of the Expediency Social Media for Culinary Products Marketing on Micro and Middle Enterprise in Pekanbaru City

    Science.gov (United States)

    Arisandi, Diki; Sukri

    2017-12-01

    Today, there are many culinary business can be found Pekanbaru city. To increase the benefit, the culinary entrepreneurs are using social media such as Facebook, twitter, instagram, whatsapp and others. This research discussed about the expediency of social media analysis for culinary products marketing on micro and middle enterprise in Pekanbaru by using structural equation modeling method. The Variables were used in this research are the selection of social media, updating information, response to costumers, quality and price as variable x to culinary business marketing as variable y. Data retrieval comes from a questionnaire filled by culinary entrepreneurs who are using social media to sell their product to customer in Pekanbaru. The result of this research displayed that the value of validity to the questionnaire was minimum = 0.083 and maximum = 0.547, RMSEA = 0.08, AGFI = 0.705, CMIN / DF = 1.834, TLI = 0.813 and CFI = 0.843. From the results of these measurements can be concluded that six of seven components of the measurement value can be avowed as acceptable, so the final result in this research is all the x variables have a positive influence on y variable.

  12. Problemas de violência ocupacional em um serviço de urgência hospitalar da Cidade de Londrina, Paraná, Brasil

    Directory of Open Access Journals (Sweden)

    Eliene Simões Cezar

    2006-01-01

    Full Text Available A violência no trabalho é um fator atualmente preocupante nos hospitais. Este estudo teve como objetivos caracterizar os problemas de violência ocupacional, detectados pelos trabalhadores da equipe de saúde do serviço de urgência hospitalar. Estudo exploratório e transversal, com abordagem quantitativa dos dados, foi realizado no serviço de urgência de um hospital geral da Cidade de Londrina, Paraná, Brasil. População composta por 33 trabalhadores da equipe de enfermagem e 14 médicos. Dados coletados por meio de entrevistas realizadas com os trabalhadores e com os gestores do serviço médico e de enfermagem, e consulta aos registros de violência dos últimos sete anos. Os resultados mostraram que 100% dos enfermeiros, 88,9% dos técnicos, 88,2% dos auxiliares de enfermagem e 85,7% dos médicos referiram ter sido vítimas de atos de violência no trabalho, embora não registradas. Tipo de violência sofrida: 95,2% agressão verbal; 33,3% por assédio moral e assédio sexual, respectivamente. Medidas preventivas para a violência ocupacional devem ser implementadas.

  13. Expedient Route To Access Rare Deoxy Amino l-Sugar Building Blocks for the Assembly of Bacterial Glycoconjugates.

    Science.gov (United States)

    Sanapala, Someswara Rao; Kulkarni, Suvarn S

    2016-04-13

    Bacterial glycoproteins and oligosaccharides contain several rare deoxy amino l-sugars which are virtually absent in the human cells. This structural difference between the bacterial and host cell surface glycans can be exploited for the development of carbohydrate based vaccines and target specific drugs. However, the unusual deoxy amino l-sugars present in the bacterial glycoconjugates are not available from natural sources. Thus, procurement of orthogonally protected rare l-sugar building blocks through efficient chemical synthesis is a crucial step toward the synthesis of structurally well-defined and homogeneous complex glycans. Herein, we report a general and expedient methodology to access a variety of unusual deoxy amino l-sugars starting from readily available l-rhamnose and l-fucose via highly regioselective, one-pot double serial and double parallel displacements of the corresponding 2,4-bistriflates using azide and nitrite anions as nucleophiles. Alternatively, regioselective monotriflation at O2, O3, and O4 of l-rhamnose/l-fucose allowed selective inversions at respective positions leading to diverse rare sugars. The orthogonally protected deoxy amino l-sugar building blocks could be stereoselectively assembled to obtain biologically relevant bacterial O-glycans, as exemplified by the first total synthesis of the amino linker-attached, conjugation-ready tetrasaccharide of O-PS of Yersinia enterocolitica O:50 strain 3229 and the trisaccharide of Pseudomonas chlororaphis subsp. aureofaciens strain M71.

  14. World AIDS day 1991 observances urge sharing the challenge.

    Science.gov (United States)

    1992-01-01

    The Region of the Americas took part in World AIDS DAy 1991, whose theme, "Sharing the Challenge," urged all sectors of society to support AIDS-related education, services, and advocacy. The day of observance was intended to encourage the participation of public, private, nongovernmental, and religious leaders in promoting AIDS-related activities. Although World AIDS Day took place on December 1, activities in the Region of the Americans began from the last week of November and into the first week of December. Most of these activities were designed to educate the public on how to avoid infection, as well as inform and sensitize audiences on the health and social needs of those infected. These activities took the form of press conferences, exhibitions, lectures, public concerts, television adds, etc. One such activity, sponsored by the Pan American Health Organization (PAHO) and held at its headquarters in Washington, D.C., focused on the AIDS crisis and the need for educational activities. The program opened with a speech by Dr. Carlyle Guerra de Macedo, PAHO's director, who warned against complacency in confronting the disease. US Surgeon General Antonia Novello also spoke at the occasion, addressing the growing threat of AIDS among women. Already, 12% of AIDS victims in the US are women, and heterosexual transmissions of AIDS will likely continued to increase. Pointing out that a vaccine is not expected in the short term, PAHO's Dr. David Brandling-Bennet stressed that the fight against AIDS depends on disseminating information. The PAHO meeting also featured a panel discussion composed of educators and health professionals, who discussed the educational responsibility of television in transmitting the AIDS-prevention message to the public.

  15. Una disciplina-quadro delle libertà di religione: perché, oggi più di prima, urge “provare e riprovare” a mettere al sicuro la pace religiosa

    Directory of Open Access Journals (Sweden)

    Giuseppe Casuscelli

    2017-07-01

    A Framework of Freedom of Religion: for today, it urges "to try and try again" to secure religious peaceABSTRACT: This article analyzes the theme of the continuing lack of a law on religious freedom in Italy, despite the fact that seventy years have passed since the Republican Constitution was approved. According to the Author, the combination of four macro-phenomena (security, economic crisis, immigration, populism nowadays urges the Italian Parliament to start debating how to implement the rights guaranteed under art. 19 Cost. - irrespective of the nationality of the person - and to regulate the procedures for reaching the agreements provided for in the third paragraph of art. 8 Cost. using the well-articulated bill proposed by the Astrid study group. The Author, finally, identifies a number of firm points necessary in his view to ensure respect for religious pluralism, secularism of the state and “religious peace”.

  16. Condição de urgência odontológica e fatores associados em trabalhadores da construção civil: Bahia, 2008

    Directory of Open Access Journals (Sweden)

    Luisa Silva Lima

    Full Text Available INTRODUÇÃO: O ramo da construção civil lidera as taxas de acidentes de trabalho e a sua força produtiva caracteriza-se por empregar, a baixo custo, um número significativo de força de trabalho masculina com reduzido nível de escolaridade. Em relação à saúde bucal, percebe-se que este grupo apresenta problemas bucais relevantes, que podem culminar em urgências odontológicas. OBJETIVO: O objetivo deste trabalho foi verificar a condição de urgência odontológica e os fatores sociodemográficos associados, em trabalhadores da construção civil de empresas de Salvador-BA e região metropolitana, atendidos pelo SESI-BA. MATERIAL E MÉTODO: Conduziu-se um estudo transversal com dados de 1057 trabalhadores, examinados no ano de 2008. Procedeu-se à análise descritiva de indicadores sociodemográficos e indicadores de saúde bucal, e ao teste de associação do qui-quadrado. A análise multivariada foi realizada e todas as variáveis que mostraram significância estatística com um p < 0,15 foram consideradas no modelo saturado da Análise de Regressão de Poisson Robusta. RESULTADO: Observou-se um percentual de 14% de condição de urgência e associação positiva com alta atividade de cárie (RP = 1,98 IC95% 1,32-2,64 p = 0,00 e menor grau de escolaridade (RP = 1,48 IC95% 1,01-1,95 p = 0,04. CONCLUSÃO: Os resultados mostram a necessidade do desenvolvimento de ações para tratamento dos problemas bucais instalados e ações de prevenção e promoção em saúde para melhorar a condição de saúde bucal de trabalhadores da construção civil.

  17. Perfil do Inquérito de Violências e Acidentes em Serviços Sentinela de Urgência e Emergência

    Directory of Open Access Journals (Sweden)

    Marta Maria Alves da Silva

    Full Text Available Resumo O Inquérito de Violências e Acidentes em Serviços Sentinela de Urgência e Emergência (VIVA Inquérito é o componente de vigilância sentinela do Sistema de Vigilância de Violências e Acidentes (VIVA. Sua primeira edição foi realizada em 2006; outras foram realizadas em 2007, 2009, 2011 e 2014. A amostra é composta por vítimas de acidentes e violências atendidas em serviços de urgência e emergência vinculados ao Sistema Único de Saúde (SUS. Os serviços são selecionados de forma intencional, e posteriormente é realizada uma etapa de amostragem probabilística de turnos de 12 horas, por conglomerados em único estágio de seleção. Os dados são coletados por entrevistadores treinados, com formulário padronizado. As variáveis incluem dados sobre o estabelecimento, a vítima, a ocorrência, a lesão e a evolução do caso. O VIVA Inquérito disponibiliza informações fundamentais para a implementação de políticas de enfrentamento das violências e acidentes e promoção da saúde e da paz.

  18. "Expedição portuguesa ao Muatiânvua" como fonte para a história social dos grupos de carregadores africanos do comércio de longa distância na África centro-ocidental

    Directory of Open Access Journals (Sweden)

    Elaine Ribeiro

    2013-12-01

    Full Text Available The objective of this paper is to analyze the spaces and the African agents described in Henrique de Carvalho’s Expedição portuguesa ao Muatiânvua. Considering the civilizational discourse of late nineteenth century, we intend to argue that such descriptions of the expedition routes, because they coincide with the regional trade routes and were performance spaces of different African porters, can be used as a source of social history of long-distance trade of western central Africa.

  19. An Expedient Study on Back-Propagation (BPN) Neural Networks for Modeling Automated Evaluation of the Answers and Progress of Deaf Students' That Possess Basic Knowledge of the English Language and Computer Skills

    Science.gov (United States)

    Vrettaros, John; Vouros, George; Drigas, Athanasios S.

    This article studies the expediency of using neural networks technology and the development of back-propagation networks (BPN) models for modeling automated evaluation of the answers and progress of deaf students' that possess basic knowledge of the English language and computer skills, within a virtual e-learning environment. The performance of the developed neural models is evaluated with the correlation factor between the neural networks' response values and the real value data as well as the percentage measurement of the error between the neural networks' estimate values and the real value data during its training process and afterwards with unknown data that weren't used in the training process.

  20. Premonitory Urges in Patients with Gilles de la Tourette Syndrome: An Italian Translation and a 7-Year Follow-up.

    Science.gov (United States)

    Gulisano, Mariangela; Calì, Paola; Palermo, Filippo; Robertson, Mary; Rizzo, Renata

    2015-12-01

    Premonitory sensations or urges (PUs) are described as characteristic sensory phenomena preceding tics, which are often described as unpleasant. They occur in 90% of patients affected by Gilles de la Tourette Syndrome (GTS). They may be localized (around the area of tic) or generalized (covering a wide area of the body). The PUs can be measured by the Premonitory Urge for Tics Scale (PUTS). In this study we translated the PUTS scale into Italian and then assessed children and adolescents/young people (CYP) with GTS using the scale. GTS patients were assessed at the initial interview and after 7 years to evaluate the PUs, and the correlations of the PUTS scores with tic severity, severity of comorbid disorders (obsessive-compulsive disorder [OCD], attention-deficit/hyperactivity disorder [ADHD]), and a variety of coexisting psychopathologies. A total of 95 patients were studied. We successfully translated the PUTS into Italian, and our results indicated that our translated version had good psychometric properties. Results demonstrated that the CYP had PUs at both interviews, but that older CYP were more consistent in reporting PUs than younger CYP (i.e., PUTS scores increased with age). We found no correlations between PUTS score and tic severity at either interview. We found a statistical significant correlation between PUTS score and obsessive-compulsive symptoms (OCS) at both interviews; Moreover both the PUTS and Children's Yale-Brown Obsessive Compulsive Scale (CY-BOCS) scores increased significantly, whereas the Yale Global Tic Severity Rating Scale (YGTSS) score decreased significantly. We found no relationships between PUTS scores and anxiety, depression, ADHD, and externalizing/internalizing behavioral scores. Our results suggest the the Italian translation of the PUTS has good psychometric properties. Although both younger (10 years of age, the PUs correlated with obsessions and compulsions (CY-BOCS scores).

  1. Nocturnal Polyuria in Older Women with Urge Urinary Incontinence: Role of Sleep Quality, Time in Bed and Medications Used.

    Science.gov (United States)

    Tyagi, Shachi; Perera, Subashan; Clarkson, Becky D; Tadic, Stasa D; Resnick, Neil M

    2017-03-01

    Nocturia is common and bothersome in older adults, especially those who are also incontinent. Since nocturnal polyuria is a major contributor, we examined factors associated with nocturnal polyuria in this population to identify those possibly amenable to intervention. We analyzed baseline data from 2 previously completed studies of urge urinary incontinence. The studies involved 284 women (mean age ± SD 72.9 ± 7.9 years) who also completed 3-day voiding diaries. Participants with a nocturnal polyuria index greater than 33% were categorized as having nocturnal polyuria (nocturnal polyuria index = nocturnal urinary volume per 24-hour urine volume). Associations between nocturnal polyuria and various demographic, clinical and sleep related parameters were determined. Overall 55% of the participants had nocturnal polyuria. Multivariable regression analysis revealed that age, body mass index, use of angiotensin converting enzyme inhibitor/angiotensin receptor blocker, time spent in bed and duration of first uninterrupted sleep were independent correlates of nocturnal polyuria. Participants with a larger nocturnal excretion reported a shorter duration of uninterrupted sleep before first awakening to void and worse sleep quality despite spending similar time in bed. Body mass index, use of angiotensin converting enzyme inhibitor/angiotensin receptor blockers, time in bed and duration of uninterrupted sleep before first awakening to void are independently associated with nocturnal polyuria in older women with urge urinary incontinence, and are potentially modifiable. These findings also confirm the association between sleep and nocturnal polyuria. Further studies should explore whether interventions to reduce nocturnal polyuria and/or increase the duration of uninterrupted sleep before first awakening to void would help to improve sleep quality in this population and thereby reduce or eliminate the need for sedative hypnotics. Copyright © 2017 American Urological

  2. Early pushing urge in labour and midwifery practice: a prospective observational study at an Italian maternity hospital.

    Science.gov (United States)

    Borrelli, Sara E; Locatelli, Anna; Nespoli, Antonella

    2013-08-01

    to investigate the early pushing urge (EPU) incidence in one maternity unit and explore how it is managed by midwives. The relation to some obstetric outcomes was also observed but not analysed in depth. prospective observational study. Italian maternity hospital. 60 women (44 nullips and 16 multips) experiencing EPU during labour. the total EPU incidence percentage was 7.6%. The single midwives' incidences range had a very wide margin, noting an inverse proportion between the number of diagnoses of EPU and midwife's waiting time between urge to push and vaginal examination. Two care policies were adopted in relation to the phenomenon: the stop pushing technique (n=52/60) and the 'let the woman do what she feels' technique (n=8/60). In case of stop pushing techniques, midwives proposed several combined techniques (change of maternal position, blowing breath, vocalisation, use of the bath). The EPU diagnosis at less than 8cm of cervical dilatation was associated with more medical interventions. Maternal and neonatal outcomes were within the range of normal physiology. An association between the dilatation at EPU diagnosis and obstetric outcomes was observed, in particular the modality of childbirth and perineal outcomes. this paper contributes new knowledge to the body of literature around the EPU phenomenon during labour and midwifery practices adopted in response to it. Overall, it could be argued that EPU is a physiologic variation in labour if maternal and fetal conditions are good. Midwives might suggest techniques to woman to help her to stay with the pain, such as change of position, blowing breath, vocalisation and use of the bath. However, the impact of policies, guidelines and culture on midwifery practices of the specific setting are a limitation of the study because it is not representative of other similar maternity units. Thus, a larger scale work should be considered, including different units and settings. The optimal response to the phenomenon

  3. Urgências em traumatismos dentários: classificação, características e procedimentos Dental traumatism urgencies: classification, signs and procedures

    Directory of Open Access Journals (Sweden)

    Mariane Emi Sanabe

    2009-12-01

    Full Text Available OBJETIVO: Discutir os aspectos das urgências odontológicas relacionadas aos traumatismos dentários, disponibilizando mais informações para médicos pediatras ou plantonistas de serviços de atendimento de urgências e emergências. FONTES DE DADOS: O levantamento dos dados foi realizado na base de dados Pubmed e Bireme, selecionando os artigos dos últimos 13 anos. As palavras-chave utilizadas foram: traumatismo dentário, dente decíduo e dente permanente. Os critérios de inclusão utilizados foram: artigos em inglês e português sobre incidência, prevalência e etiologia, guias de procedimentos e casos clínicos apenas de traumatismo dentário, sendo excluídos artigos de clareamento de dentes traumatizados, traumas faciais ósseos e casos clínicos de acompanhamento reduzido. SÍNTESE DOS DADOS: Os dados foram descritos de forma concisa para se tornar um guia de fácil leitura e rápido acesso em relação à conduta, necessidade de atendimento imediato e correta escolha de soluções para armazenagem dos dentes e fragmentos. CONCLUSÕES: O conhecimento sobre o assunto, a agilidade no tratamento de urgência e o correto encaminhamento do paciente proporcionam melhor prognóstico.OBJECTIVE: The aim of this literature review is to discuss the clinical aspects of dental urgencies related to dental traumatisms, providing more information for health professionals who work in emergency units, such as pediatricians or physicians on-call and nurses. DATA SOURCE: The studies were searched and selected in the Pubmed and Bireme databases, from the past 13 years. The keywords were: tooth injuries, deciduous tooth and permanent tooth. The inclusion criteria were: articles written in English and Portuguese related to incidence, prevalence, cause, guidelines and case reports of dental traumatism. Studies about dental bleaching in dental trauma, face bone trauma and reduced post-operative case reports were excluded. DATA SYNTHESIS: The data were

  4. Body weight loss, reduced urge for palatable food and increased release of GLP-1 through daily supplementation with green-plant membranes for three months in overweight women.

    Science.gov (United States)

    Montelius, Caroline; Erlandsson, Daniel; Vitija, Egzona; Stenblom, Eva-Lena; Egecioglu, Emil; Erlanson-Albertsson, Charlotte

    2014-10-01

    The frequency of obesity has risen dramatically in recent years but only few effective and safe drugs are available. We investigated if green-plant membranes, previously shown to reduce subjective hunger and promote satiety signals, could affect body weight when given long-term. 38 women (40-65 years of age, body mass index 25-33 kg/m(2)) were randomized to dietary supplementation with either green-plant membranes (5 g) or placebo, consumed once daily before breakfast for 12 weeks. All individuals were instructed to follow a three-meal paradigm without any snacking between the meals and to increase their physical activity. Body weight change was analysed every third week as was blood glucose and various lipid parameters. On days 1 and 90, following intake of a standardized breakfast, glucose, insulin and glucagon-like peptide 1 (GLP-1) in plasma were measured, as well as subjective ratings of hunger, satiety and urge for different palatable foods, using visual analogue scales. Subjects receiving green-plant membranes lost significantly more body weight than did those on placebo (p weight loss with green-plant extract was 5.0 ± 2.3 kg compared to 3.5 ± 2.3 kg in the control group. Consumption of green-plant membranes also reduced total and LDL-cholesterol (p meal tests performed on day 1 and day 90 demonstrated an increased postprandial release of GLP-1 and decreased urge for sweet and chocolate on both occasions in individuals supplemented with green-plant membranes compared to control. Waist circumference, body fat and leptin decreased in both groups over the course of the study, however there were no differences between the groups. In conclusion, addition of green-plant membranes as a dietary supplement once daily induces weight loss, improves obesity-related risk-factors, and reduces the urge for palatable food. The mechanism may reside in the observed increased release of GLP-1. Copyright © 2014 The Authors. Published by Elsevier Ltd

  5. A gestão da atenção às urgências e o protagonismo federal Management of attention to emergency rooms and the federal role

    Directory of Open Access Journals (Sweden)

    Gisele O'Dwyer

    2010-08-01

    Full Text Available O atendimento às urgências/emergências tem sido alvo de críticas e o Estado brasileiro, a partir de 2002, assume o esforço de normatizar esse nível de atenção. Este estudo objetivou analisar a política de urgência a partir dos documentos e portarias, baseando-se na teoria da estruturação (Giddens, que relaciona a mobilização de recursos alocativos e autoritários como dimensões da estrutura em interação, o que justificaria a legitimação exercida a partir da sanção das normas. A Política Nacional de Urgência (PNAU teve como marcos o financiamento federal, a regionalização, a capacitação dos profissionais, a gestão por comitês de urgência e a expansão da rede. Identifiquei a densidade das propostas documentais como a vertente facilitadora do recurso estrutural, inovadora pelas propostas de regionalização e de responsabilização dos diversos atores e pela pretensa centralidade no usuário. O financiamento do SUS, apesar do seu persistente estado de constrangimento, não teve ação coerciva sobre o investimento tecnológico. Na atual gestão, houve uma vigorosa expansão e estruturação da rede, que só foi possível por um forte aporte de recursos federais. A gestão pelos comitês precisa ser investigada e aponta-se como fragilidade a gestão do trabalho.Attention to the emergency care has been criticized, and since 2002 the Brazilian State has assumed the efforts to standardize the level of attention. It was proposed the analysis of documents and acts based on the Structuration Theory that considers the mobilization of allocative and authoritarian resources as dimensions of structure in interaction, which would justify the legitimacy exercised since the establishment of regulations. The National Emergency Plan (PNAU had as guides: the federal funding, regionalization, professional education, management by urgency committees, and the expansion of the network. It was identified the density of the documental

  6. Perfil do atendimento odontológico no Serviço de Urgência para crianças e adolescentes da Faculdade de Odontologia de Araraquara (FOAr ‒ UNESP

    Directory of Open Access Journals (Sweden)

    Yasmin Etienne ALBUQUERQUE

    Full Text Available Resumo Introdução: Atendimentos de urgência são uma prática comum em Odontopediatria, porém pouco se sabe sobre o perfil desses atendimentos. Objetivo: Avaliar o perfil dos atendimentos de urgência de crianças de 0 a 13 anos de idade realizados na Clínica Infantil da FOAr, no período de 1997 a 2012, a fim de se quantificarem os pacientes e os procedimentos realizados no Serviço, além de identificar os tratamentos mais realizados. Material e método: Neste estudo transversal observacional, os relatórios desse Serviço, fornecidos pelo Sistema Integrado de Clínicas, foram analisados quanto ao número de pacientes, aos atendimentos e ao tipo de procedimentos realizados. Os procedimentos foram classificados em sete categorias: Diagnóstico, Preventivos, Anestesia, Endodônticos, Restauradores, Cirúrgicos e Outros. Esses dados foram tabulados e submetidos a uma análise descritiva. Resultado: De 1997 a 2012, foi atendido um total de 13.849 pacientes e foram realizados 25.786 atendimentos e 86.279 procedimentos. Houve diminuição do número de pacientes atendidos a partir de 2001, mas o número de consultas e de procedimentos não diminuiu na mesma proporção. Observou-se que, durante o período de 2007 a 2012, os procedimentos de diagnóstico foram os mais realizados, seguidos pelos preventivos. Dentre os procedimentos operatórios, o mais realizado foi o restaurador, seguido dos endodônticos. Procedimentos cirúrgicos estão entre os menos realizados. Conclusão: Conclui-se que houve uma mudança no perfil dos atendimentos dentro desse Serviço. Apesar de haver uma redução no número de pacientes atendidos, o número de consultas e a quantidade de procedimentos realizados permaneceram estáveis. Os procedimentos realizados estão de acordo com o perfil do Serviço de Urgência.

  7. Clampe de Ganz no tratamento de urgência em lesões do anel pélvico Ganz clamps to treat emergencies in pelvic ring lesions

    Directory of Open Access Journals (Sweden)

    Gilberto José Cação Pereira

    2008-07-01

    Full Text Available OBJETIVO: Avaliar a eficiência do clampe de Ganz na estabilização e redução dos deslocamentos da pelve, quando utilizado no tratamento de urgência, além de aquilatar eventuais dificuldades e facilidades do método. MÉTODOS: O clampe de Ganz foi utilizado no tratamento de urgência em 31 pacientes com graves lesões do anel pélvico (Tile C associadas a importante instabilidade hemodinâmica. RESULTADO: Entre os pacientes, 27 (87,1% apresentaram evolução favorável, com estabilização, redução dos deslocamentos e compressão da região posterior do anel, além de estabilização hemodinâmica, e quatro (12,9% evoluíram para óbito. CONCLUSÃO: O clampe de Ganz mostrou-se eficiente ferramenta no tratamento de urgência das lesões do anel pélvico, por ser de concepção simples, de rápida colocação, não impedir ou dificultar procedimentos no abdome e, principalmente, por permitir a estabilização da pelve, redução dos deslocamentos e compressão na região posterior do anel, local onde ocorrem os maiores sangramentos, reduzindo-os ou eliminando-os.OBJECTIVE: To evaluate the effectiveness of Ganz clamp to stabilize and reduce pelvic dislocations in emergency situations, and to assess possible difficult and easy aspects of the method. METHOD: Ganz clamp was used in the emergency treatment of 31 patients with severe lesions of the pelvic ring (Tile C associated to major hemodynamic instability. RESULTS: Among the patients, 27 (87.1% presented a favorable evolution, with stabilization, reduction of dislocations, and compression of the posterior portion of the ring, and also hemodynamic stabilization, and 4 (12.9% died. CONCLUSION: The Ganz clamp was found to be an effective tool in the emergency treatment of pelvic ring lesions because it has an uncomplicated conception, allowing for a fast placement, because it does not prevent nor make it difficult for abdominal procedures, and most of all because it allows for the

  8. Masculinidades em jogo na América Portuguesa: a expedição de Pero Coelho de Sousa em 1603

    Directory of Open Access Journals (Sweden)

    Mário Martins Viana Júnior

    2013-12-01

    Full Text Available Neste artigo buscamos investigar algumas das contingências, transformações e invenções acerca dos aspectos de masculinidades envoltos nas trajetórias dos indivíduos que se lançaram nas atividades de conquista e colonização das capitanias do Norte da América portuguesa, durante o final do século XVI e início do século XVII, conferindo atenção especial à capitania do Siará e à expedição do capitão mor Pero Coelho Sousa, iniciada em 1603. Para tanto, analisamos relações, expectativas e comportamentos de alguns dos homens que ocuparam os principais ofícios de Sua Majestade e desenvolveram práticas de governança no Estado do Brasil, principalmente quando deliberaram sobre os avanços pelo Rio Grande, Paraíba, Siará, Piauí e Maranhão. Sob uma matriz teórica dos estudos de gênero e de masculinidades, intentamos analisar a invenção de identidades masculinas para o contexto assinalado, problematizando os elementos de identificação e diferenciação existentes entre os homens. Metodologicamente, procedemos à investigação de fontes oficiais, a exemplo de cartas, decretos e chancelas régias, além de regimentos, autos e certidões salvaguardados tanto em equipamentos brasileiros como em instituições portuguesas. Realizamos ainda a análise de livros de crônicas e memórias de religiosos e de alguns dos próprios sujeitos que se aventuraram nas atividades de conquista.

  9. Effects of smoking cues on caffeine urges in heavy smokers and caffeine consumers with and without schizophrenia.

    Science.gov (United States)

    Adolfo, Amy B; AhnAllen, Christopher G; Tidey, Jennifer W

    2009-02-01

    Cigarette smoking and caffeine use are established and problematic drug-use behaviors in people with schizophrenia. Associative links between drugs of abuse may occur but the relationship between caffeine use and cigarette smoking has received little attention in schizophrenia. In this cross-cue reactivity laboratory study, we examined the effects of neutral and smoking cues on craving for caffeinated beverages in participants with schizophrenia or schizoaffective disorder (SS; n=15) and non-psychiatric controls (CS; n=18) all of whom were heavy smokers and daily caffeine users. Participants were tested under non-abstinent and 5-hour abstinent conditions. SS tended to report greater daily levels of caffeine use than CS. Although this difference was not significant, that may be due to the small sample sizes as the size of this effect was large. Daily caffeine intake was significantly correlated with daily smoking rate in SS but not CS. A significant interaction between group and cue type after controlling for caffeine intake indicated that exposure to smoking cues increased urge for caffeinated beverages in SS but not CS. These results indicate support for associative connections between cigarette smoking cues and craving for caffeine in smokers with schizophrenia.

  10. Characterization of the Hokuyo URG-04LX laser rangefinder for mobile robot obstacle negotiation

    Science.gov (United States)

    Okubo, Yoichi; Ye, Cang; Borenstein, Johann

    2009-05-01

    This paper presents a characterization study of the Hokuyo URG-04LX scanning laser rangefinder (LRF). The Hokuyo LRF is similar in function to the Sick LRF, which has been the de-facto standard range sensor for mobile robot obstacle avoidance and mapping applications for the last decade. Problems with the Sick LRF are its relatively large size, weight, and power consumption, allowing its use only on relatively large mobile robots. The Hokuyo LRF is substantially smaller, lighter, and consumes less power, and is therefore more suitable for small mobile robots. The question is whether it performs just as well as the Sick LRF in typical mobile robot applications. In 2002, two of the authors of the present paper published a characterization study of the Sick LRF. For the present paper we used the exact same test apparatus and test procedures as we did in the 2002 paper, but this time to characterize the Hokuyo LRF. As a result, we are in the unique position of being able to provide not only a detailed characterization study of the Hokuyo LRF, but also to compare the Hokuyo LRF with the Sick LRF under identical test conditions. Among the tested characteristics are sensitivity to a variety of target surface properties and incidence angles, which may potentially affect the sensing performance. We also discuss the performance of the Hokuyo LRF with regard to the mixed pixels problem associated with LRFs. Lastly, the present paper provides a calibration model for improving the accuracy of the Hokuyo LRF.

  11. Caracterização dos acidentes de trânsito assistidos por um serviço de atendimento móvel de urgência Characterization of traffic accidents attended by a mobile urgency care service

    Directory of Open Access Journals (Sweden)

    Andréa Tayse de Lima Gomes

    2016-04-01

    Full Text Available Objetivo: Caracterizar os acidentes de trânsito assistidos pelo serviço de atendimento móvel de urgência do Rio Grande do Norte. Métodos: Pesquisa descritiva, exploratória, com abordagem quantitativa, realizada em um Serviço de Atendimento Móvel de Urgência. Resultados: A amostra foi composta por 1.353 fichas de atendimento de janeiro a junho de 2014. Destacou-se o sexo masculino (78,0%, com idade entre 25 e 34 anos (29,9%. O maior número foi no final de semana (53,9%, à noite (25,9% e o tipo de colisão mais recorrente foi queda de moto (35,8%. As escoriações foram as lesões mais frequentes (28,7% e o politraumatismo ocorreu em 34,1% das vítimas. Conclusão: Ressalta-se a importância da educação permanente dos profissionais de saúde, pois, quanto mais rápido e qualificado for o primeiro atendimento, maiores serão as chances de um bom prognóstico.

  12. Recém-nascido no Serviço de Urgência - casuística do ano 2011 de um Centro Hospitalar

    Directory of Open Access Journals (Sweden)

    Ana Ratola

    2016-02-01

    Full Text Available Introdução: O nascimento de um filho é um desafio para os pais. Assim, no período neonatal, surgem frequentemente dúvidas que motivam a ida ao Serviço de Urgência (SU, muitas vezes sem justificação clínica. Objetivos: Caracterizar as admissões de recém-nascidos (RN no SU num período de 12 meses e avaliar a justificação do atendimento pediátrico urgente. Material e métodos: Análise retrospetiva dos episódios de urgência dos RN que recorreram ao nosso hospital entre Janeiro e Dezembro de 2011. Resultados: No período em estudo, recorreram 394 RN (20% foram observados em mais do que uma ocasião, representando 1,3% das admissões no SU Pediátrico; 20% referenciados por profissionais de saúde. Os principais motivos de recurso foram queixas gastrointestinais (31%, lesões cutâneo-mucosas (18%, icterícia (17% e queixas respiratórias (15%. Foram realizados exames complementares em 44% das admissões, sendo os mais frequentes, bilirrubina transcutânea e análise de urina. Instituiu-se terapêutica em 18% dos casos. Os diagnósticos mais frequentes corresponderam a patologia neonatal benigna e problemas de puericultura em 57% dos casos (n=283. A maioria dos RN (75,6% teve alta para o domicílio. A mediana da idade materna foi de 30 anos e 58,6% eram primíparas. Metade das mães cuja escolaridade foi conhecida tinham concluído o nono ano. Conclusões: A maioria dos recursos ao SU hospitalar no período neonatal corresponde a situações não urgentes que poderiam ser resolvidos nos Cuidados Primários de Saúde. Salienta -se a importância do esclarecimento das mães durante a gravidez e período neonatal. Por outro lado, a inespecificidade de sintomas nesta faixa etária exige um maior nível de alerta para as situações potencialmente graves

  13. Are urge incontinence and aging risk factors of erectile dysfunction in patients with male lower urinary tract symptoms?

    Science.gov (United States)

    Amano, Toshiyasu; Earle, Carolyn; Imao, Tetsuya; Takemae, Katsuro

    2016-01-01

    Several studies have indicated that erectile dysfunction (ED) patients also suffer from lower urinary tract symptoms (LUTS). We investigated a group of men with LUTS and assessed their sexual function with the aim of being able to predict ED risk factors and introduce ED treatments earlier for this patient group. International Prostate Symptom Score (IPSS), Overactive Bladder Symptoms Score (OABSS) and Sexual Health Inventory for Men (SHIM) score were obtained from 236 men with LUTS at their first out-patients visit. Clinical parameters such as body mass index, prostate volume, residual urine volume and prostate specific antigen were also evaluated. The relationship between the SHIM score and other clinical data was analyzed. According to the SHIM score, ED in men with LUTS was severe 15%, moderate 19%, moderate to mild 28%, mild 17%, normal 7% and data was incomplete in 14%. Based on the results of a multivariate analysis, aging (p urinary incontinence was a risk factor for severe and moderate ED (p = 0.005). Aging and OAB (notably urinary urge incontinence) are risk factors for severe and moderate ED in men with LUTS.

  14. Predictors Of Burnout Syndrome In Nurses In The Prehospital Emergency Services [preditores Da Síndrome De Burnout Em Enfermeiros De Serviços De Urgência Pré-hospitalar

    OpenAIRE

    De Souza Franca S.P.; De Martino M.M.F.; Dos Santos Aniceto E.V.; Silva L.L.

    2012-01-01

    OBJETIVO: Analisar os preditores da Síndrome de Burnout apresentados por enfermeiros de serviços de urgência pré-hospitalar móvel. MÉTODOS: Estudo descritivo, exploratório, quantitativo com 38 enfermeiros. Utilizou-se questionário estruturado acrescido do Maslach Burnout Inventory em setembro de 2010. Na análise dos dados, foram usadas técnicas de estatística descritiva e inferencial (teste t-Student e teste F (ANOVA)). A verificação da hipótese de igualdade foi realizada pelo teste F de Leve...

  15. A Interface entre a Atenção Primária e os Serviços Odontológicos de Urgência (SOU no SUS: a interface entre níveis de atenção em saúde bucal

    Directory of Open Access Journals (Sweden)

    Silvia Carréra Austregésilo

    2015-10-01

    Full Text Available ResumoConsiderando que os serviços de urgência odontológica compõem a rede de referência e contrarreferência, interagindo na intersecção do atendimento primário, secundário e terciário, a presente pesquisa visou descrever a interface entre a atenção primária à saúde (APS, particularmente da Estratégia de Saúde da Família, e a atenção secundária em saúde bucal, utilizando-se dos Serviços Odontológicos de Urgência (SOU, no município do Recife. Trata-se de um estudo de caso qualitativo, exploratório e descritivo. A coleta de dados se deu a partir da realização de entrevistas semiestruturadas. Foi utilizada a análise clássica do ALCESTE a partir do Dendograma de Classificação Hierárquica Descendente, permitindo compreender as expressões e cada uma das palavras pronunciadas pelos profissionais de odontologia, analisando-as a partir de seus lugares e inserções sociais. Evidenciamos uma frágil integração e pouca resolutividade entre os níveis de atenção, apresentando uma rede parcialmente desconectada. Indubitavelmente os problemas com a interface entre a atenção primária e os serviços de urgência em saúde bucal são múltiplos e complexos. As soluções individuais possuem baixa efetividade, sendo estas complexas em sua operacionalização.

  16. Evaluation of intra-individual test–re-test variability of uroflowmetry in healthy women and women suffering from stress, urge, and mixed urinary incontinence

    DEFF Research Database (Denmark)

    Lunacek, Libor; Gärtner, Marcel; Krhut, Jan

    2018-01-01

    Introduction and hypothesis: The objective was to evaluate the intra-individual variability of uroflowmetry (UFM) in healthy control subjects and women suffering from stress, urge, and mixed urinary incontinence. Methods: A total of 35 healthy controls (group A) and 105 women suffering from urinary...... incontinence were enrolled in the study. Thirty-five women suffered from stress urinary incontinence (group B), 35 women suffered from mixed urinary incontinence (group C), and 35 women with overactive bladder both dry and wet (group D). All participants were asked to perform UFM measurement three times......-individual difference in any of the recorded parameters was identified among the three UFM recordings in groups A, C, and D. The intra-individual variability of the following parameters reached statistical significance in patients suffering from stress urinary incontinence (group B): Qmax (p = 0.0016), Qave (p = 0...

  17. A composição dos custos de armação e a renda das expedições de pesca da frota pesqueira artesanal da região do Médio rio Madeira, Amazonas, Brasil The composition of cost and income of fishing expedictions of small-scale fishing fleet in the Medium Madeira River region, state of Amazonas, Brazil

    Directory of Open Access Journals (Sweden)

    Renato Soares Cardoso

    2006-12-01

    Full Text Available Estudos buscando identificar as características físicas, operacionais e econômicas da frota pesqueira sediada na Amazônia Central foram efetuados, deixando lacunas sobre as características da frota nas regiões periféricas. Este trabalho teve como objetivo analisar os custos necessários para a entrada de novas embarcações na atividade pesqueira e fornecer informações relativas ao custo das expedições e da renda econômica da atividade. O estudo foi realizado na região do Médio rio Madeira e foram coletadas por intermédio de questionários, informações sobre os custos de manutenção, armação e a renda das viagens de pesca, no período de junho de 2003 a maio de 2004, junto aos proprietários ou encarregados de barcos de pesca e pescadores de canoas motorizadas. O maior investimento dos proprietários de embarcações foi para a aquisição dos apetrechos, sendo os próprios pescadores os principais financiadores. As expedições de pesca das embarcações foram financiadas por seis agentes, sendo os principais financiadores os pescadores e o frigorífico. O combustível foi o principal item dos custos a encarecer as expedições dos barcos e, combustível e gelo, como custo encarecedor para as canoas. Os armadores e encarregados de barcos de pesca ganharam em média 0,6 e 0,5 salário mínimo, respectivamente, por expedição, e os pescadores 0,3 salário mínimo, enquanto pescadores de canoas motorizadas ganharam em média 0,5 salário mínimo.Studies emphasizing the physical, operational and economics characteristics of the fishing fleet were realized, focusing the fleet based in Central Amazon but with gaps about the characteristics in peripheral regions. In this sense the work aimed to analyze the necessary costs to entry of new vessel on activity and to provide information in relation to the costs of fishing expeditions and economic revenue of fishing activity. The study was realized in the Medium Madeira River region

  18. Distúrbios relacionados ao álcool em um setor de urgências psiquiátricas. Ribeirão Preto, Brasil (1988-1990

    Directory of Open Access Journals (Sweden)

    Oliveira Eliene Reis de

    1996-01-01

    Full Text Available Este estudo apresenta o resultado de uma investigação conduzida no setor de urgências psiquiátricas do Hospital das Clínicas de Ribeirão Preto, Universidade de São Paulo (1988-1990, objetivando caracterizar distúrbios pasiquiátricos relacionados ao consumo de álcool. A amostra incluiu um total de 1.082 pacientes diagnosticados durante o período da investigação. Ao todo, 576 casos foram diagnosticados com "síndrome de dependência alcoólica", 379 com "psicose alcoólica" e 127 pacientes com "álcool sem dependência". A maioria dos atendimentos recaiu sobre pacientes do sexo masculino e o grupo de idade mais afetado foi, para ambos os sexos, o de 25-44 anos. O estudo chama atenção para a importância do abuso de álcool como um problema em saúde pública.

  19. Conservative treatment of urge urinary incontinence in women: a systematic review of randomized clinical trials.

    Science.gov (United States)

    Berghmans, L C; Hendriks, H J; De Bie, R A; van Waalwijk van Doorn, E S; Bø, K; van Kerrebroeck, P E

    2000-02-01

    To assess the efficacy of physical therapies for first-line use in the treatment of urge urinary incontinence (UUI) in women, using a systematic review of randomized clinical trials (RCTs). A computer-aided and manual search was carried out for RCTs published between 1980 and 1999 investigating the treatment of UUI defined by the keywords 'physical therapies', e.g. bladder (re)training (including 'behavioural' treatment), pelvic floor muscle (PFM) exercises, with or without biofeedback and/or electrical stimulation. The methodological quality of the included trials was assessed using methodological criteria, based on generally accepted principles of interventional research. Fifteen RCTs were identified; the methodological quality of the studies was moderate, with a median (range) score of 6 (3-8.5) (maximum possible 10). Eight RCTs were considered of sufficient quality, i.e. an internal validity score of >/= 5.5 points on a scale of 0-10, and were included in a further analysis. Based on levels-of-evidence criteria, there is weak evidence to suggest that bladder (re)training is more effective than no treatment (controls), and that bladder (re)training is better than drug therapy. Stimulation types and parameters in the studies of electrical stimulation were heterogeneous. There is insufficient evidence that electrical stimulation is more effective than sham electrical simulation. To date there are too few studies to evaluate effects of PFM exercise with or without biofeedback, and of toilet training for women with UUI. Although almost all studies included reported positive results in favour of physical therapies for the treatment of UUI, more research of high methodological quality is required to evaluate the effects of each method in the range of physical therapies.

  20. Trial Protocol: Randomised controlled trial of the effects of very low calorie diet, modest dietary restriction, and sequential behavioural programme on hunger, urges to smoke, abstinence and weight gain in overweight smokers stopping smoking

    Directory of Open Access Journals (Sweden)

    Hajek Peter

    2010-10-01

    Full Text Available Abstract Background Weight gain accompanies smoking cessation, but dieting during quitting is controversial as hunger may increase urges to smoke. This is a feasibility trial for the investigation of a very low calorie diet (VLCD, individual modest energy restriction, and usual advice on hunger, ketosis, urges to smoke, abstinence and weight gain in overweight smokers trying to quit. Methods This is a 3 armed, unblinded, randomized controlled trial in overweight (BMI > 25 kg/m2, daily smokers (CO > 10 ppm; with at least 30 participants in each group. Each group receives identical behavioural support and NRT patches (25 mg(8 weeks,15 mg(2 weeks,10 mg(2 weeks. The VLCD group receive a 429-559 kcal/day liquid formula beginning 1 week before quitting and continuing for 4 weeks afterwards. The modest energy restricted group (termed individual dietary and activity planning(IDAP engage in goal-setting and receive an energy prescription based on individual basal metabolic rate(BMR aiming for daily reduction of 600 kcal. The control group receive usual dietary advice that accompanies smoking cessation i.e. avoiding feeling hungry but eating healthy snacks. After this, the VLCD participants receive IDAP to provide support for changing eating habits in the longer term; the IDAP group continues receiving this support. The control group receive IDAP 8 weeks after quitting. This allows us to compare IDAP following a successful quit attempt with dieting concurrently during quitting. It also aims to prevent attrition in the unblinded, control group by meeting their need for weight management. Follow-up occurs at 6 and 12 months. Outcome measures include participant acceptability, measured qualitatively by semi-structured interviewing and quantitatively by recruitment and attrition rates. Feasibility of running the trial within primary care is measured by interview and questionnaire of the treatment providers. Adherence to the VLCD is verified by the presence of

  1. Trial Protocol: randomised controlled trial of the effects of very low calorie diet, modest dietary restriction, and sequential behavioural programme on hunger, urges to smoke, abstinence and weight gain in overweight smokers stopping smoking.

    Science.gov (United States)

    Lycett, Deborah; Hajek, Peter; Aveyard, Paul

    2010-10-07

    Weight gain accompanies smoking cessation, but dieting during quitting is controversial as hunger may increase urges to smoke. This is a feasibility trial for the investigation of a very low calorie diet (VLCD), individual modest energy restriction, and usual advice on hunger, ketosis, urges to smoke, abstinence and weight gain in overweight smokers trying to quit. This is a 3 armed, unblinded, randomized controlled trial in overweight (BMI > 25 kg/m2), daily smokers (CO > 10 ppm); with at least 30 participants in each group. Each group receives identical behavioural support and NRT patches (25 mg(8 weeks),15 mg(2 weeks),10 mg(2 weeks)). The VLCD group receive a 429-559 kcal/day liquid formula beginning 1 week before quitting and continuing for 4 weeks afterwards. The modest energy restricted group (termed individual dietary and activity planning(IDAP)) engage in goal-setting and receive an energy prescription based on individual basal metabolic rate(BMR) aiming for daily reduction of 600 kcal. The control group receive usual dietary advice that accompanies smoking cessation i.e. avoiding feeling hungry but eating healthy snacks. After this, the VLCD participants receive IDAP to provide support for changing eating habits in the longer term; the IDAP group continues receiving this support. The control group receive IDAP 8 weeks after quitting. This allows us to compare IDAP following a successful quit attempt with dieting concurrently during quitting. It also aims to prevent attrition in the unblinded, control group by meeting their need for weight management. Follow-up occurs at 6 and 12 months.Outcome measures include participant acceptability, measured qualitatively by semi-structured interviewing and quantitatively by recruitment and attrition rates. Feasibility of running the trial within primary care is measured by interview and questionnaire of the treatment providers. Adherence to the VLCD is verified by the presence of urinary ketones measured weekly. Daily

  2. Jejum inferior a oito horas em cirurgias de urgência e emergência versus complicações

    Directory of Open Access Journals (Sweden)

    Adelita de Jesus Carvalho Martins

    2016-08-01

    Full Text Available RESUMO Objetivo: verificar a ocorrência de complicações intraoperatórias e pós-operatórias em pacientes submetidos a procedimentos cirúrgicos de urgência e emergência entre janeiro e dezembro de 2012, com tempo de jejum inferior a oito horas. Método: conduziu-se um estudo quantitativo, tipo coorte retrospectivo, por meio da análise de prontuários médicos. Resultados: foram incluídos 181 prontuários de pacientes submetidos a procedimentos cirúrgicos com duração média de 59,4 minutos, destacando-se a cirurgia de correção de fraturas em 32% dos casos. Foram observadas complicações em 36 (19,9% dos pacientes, destacando-se o vômito (47,2%; seguido de náuseas (16,7%; necessidade de transfusão sanguínea (13,9%; infecção do sítio cirúrgico (11,1%; e óbito (11,1%. O tempo médio de jejum foi de 133,5 minutos. O tempo de jejum não apresentou correlação estatisticamente significante com as complicações investigadas. Conclusão: as complicações intraoperatórias e pós-operatórias estiveram associadas às condições clínicas dos pacientes e não ao tempo de jejum.

  3. Prevalença i perfil sociodemogràfic del maltractament psíquic, físic i sexual en les pacients d’urgències a la regió de Múrcia

    OpenAIRE

    González Morga, Natalia; García Guillamón, Glória; Brando Asensio, Immaculada

    2014-01-01

    La violència de gènere és un fenomen parcialment visible en la societat del segle XXI. Amb aquest estudi es pretén determinar la prevalença de violència de gènere en dones que van a urgències per altres patologies i relacionar la presència del maltractament psicològic, físic i sexual amb diferents variables sociodemogràfiques per establir el perfil de la dona víctima del maltractament encobert en l’escenari estudiat. Per fer-ho, 151 dones, pacients de l’Hospital General Universitari Morales M...

  4. Fukushima Ministerial Conference Urges Continued Work to Strengthen Nuclear Safety

    International Nuclear Information System (INIS)

    2012-01-01

    Full text: Strengthening nuclear safety is a continuous process that leaves no room for complacency, the Co-Presidents of the Fukushima Ministerial Conference on Nuclear Safety said in a statement today. Koichiro Gemba, Japan's Minister of Foreign Affairs, and Fadillah bin Haji Yusof, Malaysia's Deputy Minister of Science, Technology and Innovation, released the Co-Presidents' Statement at the conclusion of the Conference's Ministerial Plenary, on day one of the three-day event. ''It was stressed that nuclear safety is a prerequisite for the peaceful uses of nuclear energy, that strengthening nuclear safety is a continuous process and that there should be no complacency in safety matters,'' the statement said. The statement recognized progress reported by Japan in the response to the Fukushima Daiichi accident, including the achievement of the present stable status of the nuclear power station and the significant decrease in radioactive releases at the accident site. It stressed the importance of continued transparency in sharing objective information on the progress of decommissioning the plant, remediation and waste management, and encouraged Japan to lead an international effort to obtain data from the damaged reactors. ''The lessons learned from these activities, through their dissemination and related cooperation with the international community, are expected to contribute to enhancing the safety and effectiveness of future decommissioning and remediation activities worldwide,'' it said. The statement emphasized the importance of strengthening the IAEA's central role in international efforts to enhance global nuclear safety, underlining the Agency's Safety Standards and the IAEA Action Plan on Nuclear Safety. It urged IAEA Member States to strengthen efforts to implement the Action Plan fully, including the use of international peer reviews and putting the recommendations of such reviews into practice. It stressed the ''utmost importance of establishing and

  5. Acesso aos serviços de urgência e internação hospitalar por crianças de 0 a 2 anos residentes em Juiz de Fora – MG

    OpenAIRE

    Toledo, Luana Vieira

    2014-01-01

    O acesso aos serviços de saúde tem sido objeto de grande interesse na área da saúde coletiva, na qual diversos autores adotam diferentes conceitos para o tema, envolvendo aspectos relacionados aos serviços, aos usuários e a interação entre eles. Nesta pesquisa, com o objetivo de identificar como ocorre o acesso das crianças menores de 2 anos do município de Juiz de Fora aos serviços de urgência e internação hospitalar, utilizou-se como base a reflexão teórica de Mcintyre, Thiede e Birch (2009...

  6. Urge incontinence

    Science.gov (United States)

    ... and are not able to store much urine. Augmentation cystoplasty is the surgery most often performed for ... Bethesda, MD 20894 U.S. Department of Health and Human Services National Institutes of Health Page last updated: ...

  7. Reductions in biomarkers of exposure, impacts on smoking urge and assessment of product use and tolerability in adult smokers following partial or complete substitution of cigarettes with electronic cigarettes

    Directory of Open Access Journals (Sweden)

    Carl D. D’Ruiz

    2016-07-01

    Full Text Available Abstract Background Electronic cigarettes (e-cigarettes are popular alternatives to conventional cigarettes among adult smokers wishing to reduce their exposure to harmful smoke constituents. However, little information exists on the relative internal exposures resulting from the exclusive or dual use of e-cigarettes. Methods Measurements of product use; adverse events; changes in smoking urge; and blood, urine and exhaled breath biomarkers of exposure (BoE representing toxicants believed to contribute to smoking related diseases were made at baseline and after five days of product use in 105 clinically-confined smokers randomized into groups that partially or completely substituted their usual brand combustible cigarette with commercial e-cigarettes, or discontinued all nicotine and tobacco products. Results Subjects switching to e-cigarettes had significantly lower levels (29 %–95 % of urinary BoEs after 5 days. Nicotine equivalents declined by 25 %–40 %. Dual users who substituted half of their self-reported daily cigarette consumption with e-cigarettes experienced 7 %–38 % reductions, but had increases (1 %–20 % in nicotine equivalents. Blood nicotine biomarker levels were lower in the cessation (75 %–96 % and e-cigarette use groups (11 %–83 %; dual users had no significant reductions. All groups experienced significant decreases in exhaled CO (27 %–89 %. Exhaled NO increases (46 %–63 % were observed in the cessation and e-cigarette use groups; dual users had minimal changes. By Day 5, all groups had greater reductions in smoking urge compared to cessation. However, reductions were larger in the dual use group. No serious adverse events were observed. Conclusions Exposures to harmful smoke toxicants were observed to be lower in smokers who completely or partially replaced their cigarettes with e-cigarettes over five days.

  8. Reductions in biomarkers of exposure, impacts on smoking urge and assessment of product use and tolerability in adult smokers following partial or complete substitution of cigarettes with electronic cigarettes.

    Science.gov (United States)

    D'Ruiz, Carl D; Graff, Donald W; Robinson, Edward

    2016-07-11

    Electronic cigarettes (e-cigarettes) are popular alternatives to conventional cigarettes among adult smokers wishing to reduce their exposure to harmful smoke constituents. However, little information exists on the relative internal exposures resulting from the exclusive or dual use of e-cigarettes. Measurements of product use; adverse events; changes in smoking urge; and blood, urine and exhaled breath biomarkers of exposure (BoE) representing toxicants believed to contribute to smoking related diseases were made at baseline and after five days of product use in 105 clinically-confined smokers randomized into groups that partially or completely substituted their usual brand combustible cigarette with commercial e-cigarettes, or discontinued all nicotine and tobacco products. Subjects switching to e-cigarettes had significantly lower levels (29 %-95 %) of urinary BoEs after 5 days. Nicotine equivalents declined by 25 %-40 %. Dual users who substituted half of their self-reported daily cigarette consumption with e-cigarettes experienced 7 %-38 % reductions, but had increases (1 %-20 %) in nicotine equivalents. Blood nicotine biomarker levels were lower in the cessation (75 %-96 %) and e-cigarette use groups (11 %-83 %); dual users had no significant reductions. All groups experienced significant decreases in exhaled CO (27 %-89 %). Exhaled NO increases (46 %-63 %) were observed in the cessation and e-cigarette use groups; dual users had minimal changes. By Day 5, all groups had greater reductions in smoking urge compared to cessation. However, reductions were larger in the dual use group. No serious adverse events were observed. Exposures to harmful smoke toxicants were observed to be lower in smokers who completely or partially replaced their cigarettes with e-cigarettes over five days.

  9. Preliminary Evidence of Reduced Urge to Cough and Cough Response in Four Individuals following Remote Traumatic Brain Injury with Tracheostomy

    Directory of Open Access Journals (Sweden)

    Erin Silverman

    2016-01-01

    Full Text Available Cough and swallow protect the lungs and are frequently impaired following traumatic brain injury (TBI. This project examined cough response to inhaled capsaicin solution challenge in a cohort of four young adults with a history of TBI within the preceding five years. All participants had a history of tracheostomy with subsequent decannulation and dysphagia after their injuries (resolved for all but one participant. Urge to cough (UTC and cough response were measured and compared to an existing database of normative cough response data obtained from 32 healthy controls (HCs. Participants displayed decreased UTC and cough responses compared to HCs. It is unknown if these preliminary results manifest as a consequence of disrupted sensory (afferent projections, an inability to perceive or discriminate cough stimuli, disrupted motor (efferent response, peripheral weakness, or any combination of these factors. Future work should attempt to clarify if the observed phenomena are borne out in a larger sample of individuals with TBI, determine the relative contributions of central versus peripheral nervous system structures to cough sensory perceptual changes following TBI (should they exist, and formulate recommendations for systematic screening and assessment of cough sensory perception in order to facilitate rehabilitative efforts. This project is identified with the National Clinical Trials NCT02240329.

  10. Emotional eating and routine restraint scores are associated with activity in brain regions involved in urge and self-control.

    Science.gov (United States)

    Wood, Samantha M W; Schembre, Susan M; He, Qinghua; Engelmann, Jeffrey M; Ames, Susan L; Bechara, Antoine

    2016-10-15

    Researchers have proposed a variety of behavioral traits that may lead to weight gain and obesity; however, little is known about the neurocognitive mechanisms underlying these weight-related eating behaviors. In this study, we measured activation of reward circuitry during a task requiring response and inhibition to food stimuli. We assessed participants' emotional eating, external eating, and two subscales of dietary restraint-routine restraint and compensatory restraint-using the Weight-Related Eating Questionnaire. For routine restraint, we found positive associations with activation in the insula, dorsolateral prefrontal cortex, anterior cingulate cortex, orbitofrontal cortex and ventromedial prefrontal cortex in response to high-calorie versus low-calorie foods. For emotional eating, we found positive associations with insula and dorsolateral prefrontal cortex activation in response to high-calorie versus low-calorie foods. We also found positive associations between emotional eating and dorsolateral prefrontal cortex activation in response to approach versus inhibition towards high-calorie foods. Thus, our results demonstrate an increase in activation across brain regions related to self-control and urges in response to high-calorie food associated with both emotional eating and routine restraint. Overall, these results support the construct validity of both emotional eating and routine restraint and provide preliminary evidence that these subscales have similar neural correlates. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Lesões provocadas por armas de fogo atendidas em serviços de urgência e emergência brasileiros

    Directory of Open Access Journals (Sweden)

    Adalgisa Peixoto Ribeiro

    Full Text Available Resumo O artigo objetiva analisar os atendimentos de pessoas lesionadas por armas de fogo, em serviços de urgência e emergência brasileiros, em 2014. Realizou-se um estudo transversal dos atendimentos de pacientes com lesões por arma de fogo, em 24 capitais brasileiras e no Distrito Federal, incluídos no VIVA Inquérito. Foram calculadas frequências simples e relativas das variáveis relacionadas aos pacientes e ao evento e foi ajustado um modelo logístico para amostras complexas tendo como desfecho os atendimentos a pacientes com lesões por arma de fogo. Os resultados mostram que 0,7% dos atendimentos por outros acidentes (exceto os de transporte, 1,5% por lesões autoprovocadas, 15,9% por agressões e 65,1% por intervenção legal foram provocados por arma de fogo. Houve predomínio de atendimentos a pacientes do sexo masculino, de adultos jovens (20 a 39 anos, de cor da pele parda e com baixa escolaridade. Os membros e múltiplos órgãos foram os locais mais atingidos. Conclui-se discutindo sobre os esforços para o controle de armas de fogo em circulação no país e como elas podem potencializar desfechos graves e letais em brigas e conflitos interpessoais.

  12. Anticholinergic versus botulinum toxin A comparison trial for the treatment of bothersome urge urinary incontinence: ABC trial.

    Science.gov (United States)

    Visco, Anthony G; Brubaker, Linda; Richter, Holly E; Nygaard, Ingrid; Paraiso, Marie Fidela; Menefee, Shawn A; Schaffer, Joseph; Wei, John; Chai, Toby; Janz, Nancy; Spino, Cathie; Meikle, Susan

    2012-01-01

    This trial compares the change in urgency urinary incontinence episodes over 6 months, tolerability and cost effectiveness between women receiving daily anticholinergic therapy plus a single intra-detrusor injection of saline versus a single intra-detrusor injection of 100 U of botulinum toxin A plus daily oral placebo tablets. We present the rationale and design of a randomized-controlled trial, Anticholinergic versus Botulinum Toxin, Comparison Trial for the Treatment of Bothersome Urge Urinary Incontinence: ABC trial, conducted by the NICHD-funded Pelvic Floor Disorders Network. We discuss the innovative nature of this trial and the challenges related to choice of patient population, maintaining masking, cost effectiveness, ethical considerations, measuring adherence, and placebo development and testing. Enrollment began in April, 2010. 242 participants will be randomized and primary outcome data analysis is anticipated to begin in mid 2012. Several challenges in the trial design are discussed. Randomization to placebo intra-detrusor injections may limit recruitment, potentially impacting generalizability. Other challenges included the heavy marketing of drugs for overactive bladder which could impact recruitment of drug-naïve women. In addition, anticholinergic medications often cause dry mouth, making masking difficult. Finally, adverse reporting of transient urinary retention is challenging as there is no standardized definition; yet this is the most common adverse event following intra-detrusor botulinum toxin injection. The ABC trial will help women with urgency urinary incontinence balance efficacy, side effects and cost of anticholinergic medication versus botulinum toxin intra-detrusor injection. The results have the potential to fundamentally change the therapeutic approach to this condition. Copyright © 2011 Elsevier Inc. All rights reserved.

  13. Análise epidemiológica das causas externas em unidades de urgência e emergência em Cuiabá/Mato Grosso Epidemiological analysis of external causes at urgency and emergency services in Cuiabá/Mato Grosso

    Directory of Open Access Journals (Sweden)

    Ligia Regina de Oliveira

    2008-09-01

    Full Text Available OBJETIVO: Apesar da importância das causas externas como problema de saúde pública, pouco se conhece sobre a demanda de serviços de urgência e emergência. Este estudo tem como objetivo caracterizar a morbidade por causas externas em unidades de urgência e emergência do município de Cuiabá/MT. MÉTODO: Trata-se de um estudo transversal e descritivo. Foram analisadas 3.786 vítimas de causas externas atendidas pelas cinco unidades de urgência e emergência da Secretaria Municipal de Saúde de Cuiabá/MT, no período de 1 de maio a 30 de junho de 2005. RESULTADOS: Aproximadamente 88% dos atendimentos se referiam a vítimas de acidentes, 9% corresponderam a agressões e 2% a lesões autoprovocadas. Os acidentes de transportes representaram 22% dos atendimentos, sendo os motociclistas as principais vítimas (49%; as quedas foram as causas mais freqüentes no grupo de outras causas externas de traumatismos acidentais. A prevalência em homens superou a de mulheres. A maior parte das vítimas era menor de 40 anos (79%. No entanto, a análise por tipo de causa externa apresenta resultados diferentes segundo sexo e faixa etária. Cerca da metade dos eventos ocorreu em casa e, em sua maioria, as vítimas receberam alta após o atendimento, sendo que a taxa de mortalidade foi baixa (0,4%. CONCLUSÃO: Os resultados revelam a importância da análise sistemática dos dados referentes às vítimas de acidentes e violência atendidas em unidades de urgência e emergência, como complemento às informações sobre mortalidade e morbidade hospitalar visando o monitoramento dessas causas.OBJECTIVE: Despite the importance of external causes as a public health problem, little is known about the demand for emergency services. This study aims to characterize the morbidity due to external causes in emergency units of Cuiabá/MT. METHOD: This is a cross-sectional and descriptive study. We analyzed 3,786 victims of external causes seen at five emergency units

  14. Educação ao ar livre pela aventura: o aprendizado de valores morais em expedições à natureza Education outdoors through adventure: learning moral values in nature expeditions

    Directory of Open Access Journals (Sweden)

    Flavio Theodor Kunreuther

    2012-06-01

    Full Text Available A educação ao ar livre, por meio de cursos no formato expedição, ainda acontece de forma tímida no Brasil. Entende-se por expedição uma experiência educacional contínua, de múltiplos dias, em que alunos e instrutores aventuram-se em um trajeto em área remota da natureza de forma autossuficiente. O presente estudo analisa os cursos desse tipo. Por meio de entrevistas e questionários semiestruturados, investigou-se a aprendizagem dos alunos segundo suas próprias percepções e as dos educadores da instituição, com ênfase no desenvolvimento moral do indivíduo. Como parte do estudo de caso sobre um aluno adolescente participante de um dos cursos, entrevistou-se também uma psicóloga que coordena um abrigo para menores. Os resultados encontrados indicam que os cursos de educação ao ar livre caracterizam-se por experiências que estimulam trabalhos em grupo, debates sobre justiça e solidariedade, e reflexões sobre valores e princípios como coragem, esforço pessoal, disciplina, respeito e superação de limites. Os resultados também indicam que tal proposta educacional aufere experiências sensíveis e de conexão do ser humano com a natureza. Muito embora haja potencial educacional para a educação ao ar livre, a atuação do educador perante seus alunos é fundamental para que as experiências sejam física e psicologicamente seguras, alcancem seus potenciais pedagógicos de desenvolvimento da moralidade e ajudem as pessoas a desenvolverem uma consciência ambiental, manifestada por meio de ações concretas ao retornarem dos cursos para suas comunidades.Open air education through courses organized as expeditions is still incipient in Brazil. We understand an expedition as a continued educational experience taking several days in which students and instructors venture into a remote natural area in a self-sufficient way. The present study analyzes courses of this type. Using interviews and semi-structured questionnaires, it

  15. Probing smoking craving with a multidimensional approach: validation of the 12-item French-language version of the Questionnaire on Smoking Urges

    Directory of Open Access Journals (Sweden)

    Dethier V

    2014-08-01

    Full Text Available Vincent Dethier,1 Alexandre Heeren,1,2 Laurence Galanti,3 Pierre Philippot,1 Joël Billieux1 1Laboratory for Experimental Psychopathology, Psychological Science Research Institute, Université catholique de Louvain, Louvain-la-Neuve, Belgium; 2National Fund for Scientific Research, Brussels, Belgium; 3Department of Clinical Biology, Mont-Godinne University Hospital, Yvoir, Belgium Background: The current study examined the psychometric properties of the 12-item French-language version of the Questionnaire on Smoking Urges (QSU-12, a widely used multidimensional measure of cigarette craving. Methods: Daily smokers (n=230 completed the QSU-12, the Fägerstrom Test for Nicotine Dependence, and items about addiction-related symptoms. Additional participants (n=40 completed the QSU-12 and the Fägerstrom Test for Nicotine Dependence and were assessed for expired carbon monoxide. Results: Consistent with studies validating the English version of the scale, confirmatory factor analyses supported a two-factor solution in the French version of the scale. Good scale and subscales reliabilities were observed, and convergent validity was evidenced through relationships with dependence and addiction-related symptoms. Conclusion: The French-language version of the QSU-12 is an adequate instrument to assess the multidimensional construct of craving in both research and clinical practice. Keywords: tobacco, smoking, nicotine, craving, measurement model, psychometrics, confirmatory factor analyses, carbon monoxide, addiction

  16. Política criminal e Lei Maria da Penha: o deferimento do comparecimento do agressor a programas de recuperação e reeducação como a principal medida protetiva de urgência

    OpenAIRE

    da Silva e Silva, Artenira; Sousa da Silva Barbosa, Gabriella

    2017-01-01

    A Lei Maria da Penha possui natureza marcadamente penal. Ocorre que a punição penal estatal, entendida apenas como a determinação de prisão do agressor, nos casos de violência doméstica não encontra efetiva resposta social quanto à diminuição dos casos albergados pela lei. Busca-se a utilização da previsão legal de comparecimento do agressor a programas de recuperação e reeducação como a principal medida de urgência a ser deferida como mecanismo efetivamente capaz de diminuir a reincidência d...

  17. The URban Greenhouse gas Emissions assessment through inverse modeling (URGE) project: a pilot study in the Oslo area

    Science.gov (United States)

    Pisso, I. J.; Lopez-Aparicio, S.; Schneider, P.; Schmidbauer, N.; Vogt, M.

    2017-12-01

    Norway has set the target of cutting greenhouse gas (GHG) emissions by at least 40% compared to 1990 levels by 2030. This goal will require the implementation of policy measures aiming at strong reductions of GHGs emissions, especially in the urban environment. The implementation of urban policy measures is still a challenging task and it requires control and verification for success. The URGE project aims at assessing the emission flux of GHGs including comprehensive uncertainty estimates based on inverse transport modelling techniques and optimized use of measurements. The final goal is to establish a coherent and consistent GHG urban emission inventory. This will be carried out in a case study in Oslo (Norway), where CO2 will be the priority compound. The overall outcome of the project will provide support in the development of strategies to effectively reduce GHG emissions in the urban environment. The overall goal will be reached through establishing the baseline urban CO2 emission inventory for Oslo; determining the optimal measurement locations based on transport modelling (with flexpart-wrf); designing and carrying out a pilot measurement campaign of the CO2-rich air downwind of the city plume combining state-of-the-art instruments (Picarro) and small sensors; assessing the feasibility of determining the background concentration surrounding the city with satellite measurements (OCO2); and providing optimised estimates of the emissions and their uncertainties via inverse modelling (source-receptor relationship). One of our main interests is the interoperability and exchange of information with similar activities in other urban areas. We will present the overall project and the preliminary results of the network design. We will discuss the data exchange formats, the algorithms and data structures that could be used for results and methodology intercomparisons as well as the suitability to apply the same techniques to other atmospheric compounds.

  18. Comprehensive Assessment of Compliance with Antimuscarinic Drug Treatment in the Case of Urge Urinary Incontinence of Older Patients.

    Science.gov (United States)

    Kosilov, Kirill V; Loparev, Sergey A; Kuzina, Irina G; Shakirova, Olga V; Zhuravskaya, Natalya S; Lobodenko, Alexandra

    2017-01-01

    To investigate the heterogeneous factors affecting the stability of patients older than 60 years in the UI treatment with Antimuscarinics. The prevalence of Urge Incontinence (UI) in older persons reaches 29.3%. The symptoms of urinary incontinence in older people reduce the health related life quality. In 1257 patients over 60 years (857 (68.2%) women - average age 67.8, 400 (31.8%) men - 71.4), who received AM for one year, demographic, socio-economic and health parameters were studied. OABq-SF questionnaires, MOS SF-36, urination diaries, uroflowmetry, income information from the tax offices and outpatient records were used. The compliance to AM treatment within 6 months was retained in 44.2%, and within the year - 26.8% of older patients. At least 40% of the total number of patients refused to continue the treatment for medical reasons. The persons taking Solifenacin (p≤ 0.01), Trospium (p≤ 0.05), or Darifenacin (p≤ 0.05), suffering from severe UI symptoms (p≤ 0.01), and experiencing minor side effects (p≤ 0.01), well-informed about UI treatment methods (p≤ 0.01) prevailed among the treatment compliant patients. At least 20.4% of the patients discontinued their treatment due to economic reasons. The persons with significantly larger annual income (p≤ 0.05) and annual medical cost (p≤ 0.01) prevailed among the treatment compliant patients. About 12.2% of the patients stopped their treatment for reasons related to the social background and psychological status. In this experiment, we found that AM treatment compliance in older patients, in addition to medical parameters and health conditions, is largely affected by the economic as well as social, demographic and psychological factors. The study results can be claimed by practitioners involved in correcting UI symptoms in older people. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  19. Dificultades para la atención en los servicios de urgencias: la espera inhumana Dificuldades para o atendimento nos serviços de urgências: A espera desumana Difficulties for care in the emergency room services: the in- human wait

    Directory of Open Access Journals (Sweden)

    Martha Adiela Lopera Betancur

    2010-03-01

    Full Text Available Objetivo: comprender el proceso de recibir la atención de urgencias para los pacientes y su familia. Metodología: el trabajo fue realizado con personas adultas de ambos sexos que consultaron en servicios de urgencias de la ciudad de Medellín (Colombia. Se utilizó un enfoque cualitativo, con herramientas de la etnografía focalizada, se realizaron 9 entrevistas y 50 horas de observación. El análisis se hizo a partir de los diarios de campo y las entrevistas, se extractaron códigos que luego fueron agrupados en las categorías que mejor representaran el fenómeno estudiado. Resultados: las personas acuden a los servicios de urgencias buscando atención, pero al llegar allí encuentran una serie de barreras que deben sortear para poder ser admitidos, recibir información y poder recibir compañía. En la atención de urgencias hay un desencuentro entre tres miradas: la primera es la de los participantes, que la consideran inhumana; la segunda es la del sistema de salud, que la considera un conjunto de actividades que garantizan una atención oportuna y de calidad; y la tercera es la que muestran otras investigaciones que han encontrado barreras de acceso para ser admitido y para obtener información. Conclusión: hay una serie de barreras para que los pacientes reciban atención en los servicios de urgencias en las instituciones estudiadas.Objetivo: compreender o processo de receber o atendimento de urgências para os pacientes e sua família. Metodologia: o trabalho foi realizado com pessoas adultas de ambos sexos que conferiram em serviços de urgências da cidade de Medellín (Colômbia. Utilizou-se um enfoque qualitativo, com ferramentas da etnografia focalizada, realizaram-se 9 entrevistas e 50 horas de observação. A análise se fez a partir dos diários de campo e as entrevistas, se extraditaram códigos que depois foram agrupados em categorias que melhor representassem o fenômeno estudado. Resultados: as pessoas vão aos servi

  20. Shotcrete for Expedient Structural Repair

    Science.gov (United States)

    1991-12-01

    pp. 29-44. Selmer - Olsen , R., "Examples of the Behavior of Shotcrete Linings Underground," Proceedings, Shotcrete for Ground Support, The Engineering... Selmer - Olsen , R. PAPER TITLE: Examples of the Behavior of Shotcrete Linings Underground DESCRIPTIVE TITLE NOTE: -0- BOOK/REPORT TITLE: Proceedings

  1. Expedient antibiotics production: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Bienkowski, P.R.; Byers, C.H.; Lee, D.D.

    1988-05-01

    The literature on the manufacture, separation and purification, and clinical uses of antibiotics was reviewed, and a bibliography of the pertinent material was completed. Five antimicrobial drugs, penicillin V and G, (and amoxicillin with clavulanic acid), Cephalexin (a cephalosporin), tetracycline and oxytetracycline, Bacitracin (topical), and sulfonamide (chemically produced) were identified for emergency production. Plants that manufacture antibiotics in the continental United States, Mexico, and Puerto Rico have been identified along with potential alternate sites such as those where SCP, enzyme, and fermentation ethanol are produced. Detailed process flow sheets and process descriptions have been derived from the literature and documented. This investigation revealed that a typical antibiotic-manufacturing facility is composed of two main sections: (1) a highly specialized, but generic, fermentation unit and (2) a multistep, complex separation and purification unit which is specific to a particular antibiotic product. The fermentation section requires specialized equipment for operation in a sterile environment which is not usually available in other industries. The emergency production of antibiotics under austere conditions will be feasible only if a substantial reduction in the complexity and degree of separation and purity normally required can be realized. Detailed instructions were developed to assist state and federal officials who would be directing the resumption of antibiotic production after a nuclear attack. 182 refs., 54 figs., 26 tabs.

  2. Síndrome de burnout em profissionais do serviço de atendimento móvel de urgência Burnout Syndrome in urgency mobile service professionals

    Directory of Open Access Journals (Sweden)

    Laiana Maria Luz

    2017-01-01

    Full Text Available Objetivo: analisar a prevalência da Síndrome de Burnout em profissionais do Serviço de Atendimento Móvel de Urgência. Métodos: pesquisa descritiva, transversal e quantitativa, da qual participaram 32 profissionais. Os dados foram coletados por meio do Inventário Maslach de Burnout e analisados no SPSS for Windows. A pesquisa foi aprovada pelo Comitê de Ética em Pesquisa sob CAAE n° 0040.0.045.000-11. Resultados: para a equipe como um todo, houve escores altos para Desgaste Emocional (28,1% Despersonalização (21,9% e Incompetência Profissional (28,1% (escore reverso. Na equipe médica, o Desgaste Emocional e Despersonalização foram maiores quando comparado a equipe de enfermagem; e em Incompetência Profissional os escores foram mais elevados para os técnicos de enfermagem. Conclusão: a produção de maior conhecimento sobre a temática pode contribuir no cotidiano destes profissionais, visto que a síndrome manifestou-se entre os profissionais do presente estudo. Descritores: Saúde do Trabalhador, Esgotamento Profissional, Serviços Médicos de Emergência.

  3. Política criminal e Lei Maria da Penha: o deferimento do comparecimento do agressor a programas de recuperação e reeducação como a principal medida protetiva de urgência

    Directory of Open Access Journals (Sweden)

    Artenira da Silva e Silva

    2017-06-01

    Full Text Available A Lei Maria da Penha possui natureza marcadamente penal. Ocorre que a punição penal estatal, entendida apenas como a determinação de prisão do agressor, nos casos de violência doméstica não encontra efetiva resposta social quanto à diminuição dos casos albergados pela lei. Busca-se a utilização da previsão legal de comparecimento do agressor a programas de recuperação e reeducação como a principal medida de urgência a ser deferida como mecanismo efetivamente capaz de diminuir a reincidência de agressores de violência de gênero.

  4. Society of Behavioral Medicine (SBM) position statement: SBM urges Congress to preserve and increase the financing of federally funded nutrition assistance programs and services.

    Science.gov (United States)

    Behrman, Pamela; Demirci, Jill; Yanez, Betina; Beharie, Nisha; Laroche, Helena

    2018-05-03

    Deep cuts have been proposed to federally funded nutrition assistance programs, including the Supplemental Nutrition Assistance Program (SNAP); the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC); and federally subsidized school breakfast and lunch programs. Yet, these programs help parents afford healthy meals for their families, pregnant and postpartum mothers access supplemental foods and health services for themselves and their infants and young children, and children obtain the nutrition necessary for optimal school performance. Participation in these programs is linked with reductions in perinatal morbidity and mortality, improved childhood growth trajectories, enhanced school performance, and reductions in food insecurity and poverty. Given these compelling health and economic benefits, the Society of Behavioral Medicine urges Congress to protect and increase funding for federally funded nutrition assistance programs, specifically SNAP, WIC, and school breakfast and lunch programs. Per the recent (2017) recommendations of the School Nutrition Association, Congress should also resist any attempts to "block-grant" subsidized school breakfast and lunch programs, which could reduce access to these programs. It is further recommended that Congress improve the scope of implementation- and outcomes-based assessments of these programs. Finally, we recommend efforts to increase awareness of and participation in SNAP, WIC, and federally funded school meal programs for eligible individuals, children, and families.

  5. Development and Alpha Testing of QuitIT: An Interactive Video Game to Enhance Skills for Coping With Smoking Urges.

    Science.gov (United States)

    Krebs, Paul; Burkhalter, Jack E; Snow, Bert; Fiske, Jeff; Ostroff, Jamie S

    2013-09-11

    Despite many efforts at developing relapse prevention interventions, most smokers relapse to tobacco use within a few months after quitting. Interactive games offer a novel strategy for helping people develop the skills required for successful tobacco cessation. The objective of our study was to develop a video game that enables smokers to practice strategies for coping with smoking urges and maintaining smoking abstinence. Our team of game designers and clinical psychologists are creating a video game that integrates the principles of smoking behavior change and relapse prevention. We have reported the results of expert and end-user feedback on an alpha version of the game. The alpha version of the game consisted of a smoking cue scenario often encountered by smokers. We recruited 5 experts in tobacco cessation research and 20 current and former smokers, who each played through the scenario. Mixed methods were used to gather feedback on the relevance of cessation content and usability of the game modality. End-users rated the interface from 3.0 to 4.6/5 in terms of ease of use and from 2.9 to 4.1/5 in terms of helpfulness of cessation content. Qualitative themes showed several user suggestions for improving the user interface, pacing, and diversity of the game characters. In addition, the users confirmed a high degree of game immersion, identification with the characters and situations, and appreciation for the multiple opportunities to practice coping strategies. This study highlights the procedures for translating behavioral principles into a game dynamic and shows that our prototype has a strong potential for engaging smokers. A video game modality exemplifies problem-based learning strategies for tobacco cessation and is an innovative step in behavioral management of tobacco use.

  6. Acidentes envolvendo indígenas brasileiros atendidos em serviços de urgência e emergência do Sistema Único de Saúde

    Directory of Open Access Journals (Sweden)

    Edinilsa Ramos de Souza

    Full Text Available Resumo Foram analisados os acidentes ocorridos com indígenas brasileiros atendidos em serviços de urgência e emergência do Sistema Único de Saúde (SUS. Os dados provêm do Viva Inquérito de 2014, que incluiu 86 serviços de 24 capitais e do Distrito Federal. Caracterizou-se o perfil sociodemográfico dos indígenas, o evento e o atendimento. A maioria dos atendidos era do sexo masculino e tinha entre 20-39 anos. Acidentes de transporte e quedas foram os principais motivos dos atendimentos. O uso de bebida alcoólica foi informado por 5,6% dos atendidos. Nos acidentes de transporte esse uso sobe para 19,1%; 26,1% entre condutores e 22,8% nos motociclistas. Houve diferença estatística entre os sexos em relação à faixa etária, deficiência, local de ocorrência do evento, evento relacionado ao trabalho e condição da vítima no acidente de transporte. Destaca-se a importância de dar visibilidade aos acidentes com indígenas e de envolvê-los na prevenção desses eventos. A fidedignidade desses dados depende do seu adequado preenchimento nos sistemas de informações sobre saúde de indígenas.

  7. Convergent Validity of the PUTS

    Directory of Open Access Journals (Sweden)

    Valerie Cathérine Brandt

    2016-04-01

    Full Text Available Premonitory urges are a cardinal feature in Gilles de la Tourette syndrome. Severity of premonitory urges can be assessed with the Premonitory Urge for Tic Disorders Scale (PUTS. However, convergent validity of the measure has been difficult to assess due to the lack of other urge measures.We investigated the relationship between average real-time urge intensity assessed by an in-house developed real-time urge monitor, measuring urge intensity continuously for 5mins on a visual analogue scale, and general urge intensity assessed by the PUTS in 22 adult Tourette patients (mean age 29.8+/- 10.3; 19 male. Additionally, underlying factors of premonitory urges assessed by the PUTS were investigated in the adult sample using factor analysis and were replicated in 40 children and adolescents diagnosed with Tourette syndrome (mean age 12.05 +/- 2.83 SD, 31 male.Cronbach’s alpha for the PUTS10 was acceptable (α = .79 in the adult sample. Convergent validity between average real-time urge intensity scores (as assessed with the real-time urge monitor and the 10-item version of the PUTS (r = .64 and the 9-item version of the PUTS (r = .66 was good. A factor analysis including the 10 items of the PUTS and average real-time urge intensity scores revealed three factors. One factor included the average real-time urge intensity score and appeared to measure urge intensity, while the other two factors can be assumed to reflect the (sensory quality of urges and subjective control, respectively. The factor structure of the 10 PUTS items alone was replicated in a sample of children and adolescents.The results indicate that convergent validity between the PUTS and the real-time urge assessment monitor is good. Furthermore, the results suggest that the PUTS might assess more than one dimension of urges and it may be worthwhile developing different sub-scales of the PUTS assessing premonitory urges in terms of intensity and quality, as well as subjectively

  8. A Comprehensive Expedient Methods Field Manual.

    Science.gov (United States)

    1984-09-01

    percent. Water will quickly become a killer. As temperatures rise to 120 to 125 degrees farenheit , such as in an armored personnel carrier or other...of 100KW or less unless absolutely necessary, since they are not designed for parallel operation. It is sager to use a single smaller unit for each...facility (3: 12, 13). " ~102 "" ...-. o Derating Generators. Generators are rated under the standard conditions of zero to 2,000 feet above sea level

  9. LINGUISTIC INGENUITY AND POLITICAL EXPEDIENCY: THE ...

    African Journals Online (AJOL)

    This paper investigates the peculiarities in the use of the English language by former military rulers, and most especially, the former Nigerian leader General Ibrahim Babangida in his administration and suggests that Babangida deliberately manipulated language through coinages and unconventional or curious use of ...

  10. Expedient Treatment of a Collodion Baby

    Directory of Open Access Journals (Sweden)

    Michael Chung

    2011-01-01

    Full Text Available Only ~270 cases of collodion babies have been reported in the literature since 1892. As the name suggests, the term “collodion baby” refers to a phenotype that can be characterized by a yellow, shiny, tight parchment-like membrane stretched over the skin. Although the collodion membrane is only an evanescent condition of the newborn, neonatal complications can occur in 45% of all collodion babies, leading to a mortality rate of ~11% in the first few weeks of life. Most children born as collodion babies will spontaneously desquamate within 2 weeks, but may be as long as 3 months. Eventually, these children develop signs of one of several types of ichthyosis, which gives the skin the appearance of “fish scales.” We report a unique case of a Caucasian male that was born as a Collodion baby at the University of Kentucky Children's Hospital in Lexington, Kentucky. Although the impairment of the skin barrier function put the patient at risk for a number of complications, he improved significantly after being treated with emollients and antibiotics. In contrast to previous findings, we found that skin emollients were beneficial and did not increase the risk of infection.

  11. China urges rapid growth

    International Nuclear Information System (INIS)

    Hendry, S.

    1993-01-01

    This time last year China's paramount leader, Deng Xiaoping, launched the country on another bout of fast-paced economic growth and restructuring. After three years of riding out political and economic clampdown, foreign chemical companies were jerked awake by major changes in China's chemical industry. As the state becomes less involved with managing the economy, unleashing 12% gross national product growth, closer involvement with domestic factories has become attractive and essential. MCI officials say government funds will now be channeled toward clearing energy and transport bottlenecks, and chemical enterprises will be given more chance to turn a profit. They will be allowed to issue shares, seek foreign investment partners themselves, and bypass trading companies like China National Import-Export Corp. (Sinochem), the former state monopoly. Foreign analysts question whether China's finances and oil resources can support expansion. Even if they can, Cai estimates that ethylene imports will remain around the present level of 1 million tons. To further guarantee chemical supplies, China has invested in urea and polypropylene plants in the US and polystyrene plant in Hong Kong

  12. Open scientific communication urged

    Science.gov (United States)

    Richman, Barbara T.

    In a report released last week the National Academy of Sciences' Panel on Scientific Communication and National Security concluded that the ‘limited and uncertain benefits’ of controls on the dissemination of scientific and technological research are ‘outweighed by the importance of scientific progress, which open communication accelerates, to the overall welfare of the nation.’ The 18-member panel, chaired by Dale R. Corson, president emeritus of Cornell University, was created last spring (Eos, April 20, 1982, p. 241) to examine the delicate balance between open dissemination of scientific and technical information and the U.S. government's desire to protect scientific and technological achievements from being translated into military advantages for our political adversaries.The panel dealt almost exclusively with the relationship between the United States and the Soviet Union but noted that there are ‘clear problems in scientific communication and national security involving Third World countries.’ Further study of this matter is necessary.

  13. SOCMA study urges flexibility

    International Nuclear Information System (INIS)

    Kirschner, E.

    1993-01-01

    In implementing the 1990 Pollution Prevention Act, regulators and legislators should hold off on cookie-cutter, numerical goal-based requirements to allow for site and process specific programs, says a study sponsored by the Synthetic Organic Chemicals Manufacturers Association (SOCMA; Washington). Companies should have that flexibility to target their resources toward those activities that reduce pollution cost effectively, says SOCMA environmental quality committee chairman Art Gillen, who is also BASF director of environmental regulatory affairs. The study - conducted by Woodward-Clyde Consultants (Denver) - examines four batch and custom chemical manufacturing films. As in the Clean Air Act, the batch processing of SOCMA-member plants should be considered in new regulations, Gillen says. For example, the study found that most wastes are from shutdowns and cleanouts, and there are frequent charges in waste streams and raw materials. Those characteristics do not lend themselves to annual reduction goals. Also, specific goals could have a wide range of costs: measures to reduce stack air emissions run from $18/lb to $1,106/lb. SOCMA says it will present the study to Congress and the Environmental Protection Agency

  14. Laser's calibration of an AOTF-based spectral colorimeter

    Science.gov (United States)

    Emelianov, Sergey P.; Khrustalev, Vladimir N.; Kochin, Leonid B.; Polosin, Lev L.

    2003-06-01

    The paper is devoted to expedients of AOTF spectral colorimeters calibration. The spectrometer method of color values measuring with reference to spectral colorimeters on AOTF surveyed. The theoretical exposition of spectrometer data processing expedients is offered. The justified source of radiation choice, suitable for calibration of spectral colorimeters is carried out. The experimental results for different acousto-optical mediums and modes of interaction are submitted.

  15. Superconducting magnets for accelerators

    International Nuclear Information System (INIS)

    Denisov, Yu.N.

    1979-01-01

    Expediency of usage and possibilities arising in application of superconducting devices in magnetic systems of accelerators and experimental nuclear-physical devices are studied. Parameters of specific devices are given. It is emphasized that at the existing level of technological possibilities, construction and usage of superconducting magnetic systems in experimental nuclear physics should be thought of as possible, from the engineering, and expedient, from the economical viewpoints [ru

  16. Proceedings of the DICE THROW Symposium 21-23 June 1977. Volume 1

    Science.gov (United States)

    1977-07-01

    Engineering Research Facility. 27. BLAST TESTS OF EXPEDIENT SHELTERS IN THE DICE THROW EVENT- C.H. Kearny, Oak Ridge National Laboratory. 28...Agency, 1977. 10. Gaffney , E., Close-in Measurements of Airblast and Ground Shock, POR 6909, Defense Nuclear Aqency, 1977. 11. Meyer, J., Crater and...EXPEDIENT SHELTERS FIELDED BY THE OAK RIDGE NATIONAL LABORATORY; COMMAND CONTROL COMMUNICATIONS SYSTEMS FIELDED BY THE BALLISTIC RESEARCH LABORATORY AND

  17. Clinical evaluation of patients with osteomyelitis after open fractures treated at the Hospital de Urgências de Goiânia, Goiás Avaliação clínica de pacientes com osteomielite crônica após fraturas expostas tratados no Hospital de Urgências de Goiânia, Goiás

    Directory of Open Access Journals (Sweden)

    Pablo Erick Alves Villa

    2013-01-01

    Full Text Available OBJECTIVE: To evaluate clinically patients with chronic osteomyelitis after open fractures, treated in the Hospital of urgencies in Goiania. METHODS: A cross-sectional study, with data collection through questionnaire, from a review of medical records. We collected data on the type of trauma and the clinical characteristics of the patient. The hour of attendance and the injuries on the patients were collected, and then classified according to Gustilo and Anderson (1976. Samples of the lesion during the surgical procedure were collected for culture of pathogenic microorganisms. The analyzes were performed using STATA/SE version 8.0. Descriptive analysis was performed (absolute and relative frequencies and to verify existence of association between variables was performed using thur-square or Fisher's Exact Test. This study was approved by the Research Ethics Committee of the Hospital and Emergency in Goiania. RESULTS: There was predominance of male adult, presenting open fractures with increased involvement of the leg bones or in two or more bones (polytrauma. The majority of patients presented with a lesion type III (high-energy trauma. There was loss of excessive time since the time of the accident until the initial surgical care. We detected the presence of gram-positive cultures of material obtained after the diagnosis of osteomyelitis. CONCLUSIONS: The control of factors such as antibiotics, exposure time, bacterial resistance to the antimicrobial used, extensive tissue damage and location of the fracture are extremely important to the predictive effect of infection in open fractures. OBJETIVO: Avaliar clinicamente pacientes com osteomielite crônica após fraturas expostas, tratados no Hospital de Urgências de Goiânia. MÉTODOS: Estudo do tipo transversal, com coleta de dados mediante questionário, a partir de uma revisão de prontuário. Coletaram-se dados relativos ao tipo de trauma e às características clínicas do paciente. Foram

  18. Want, need and habit as drivers of smoking behaviour: A preliminary analysis.

    Science.gov (United States)

    Wehbe, Luis; Ubhi, Harveen Kaur; West, Robert

    2018-01-01

    Models of tobacco smoking behaviour propose that anticipated pleasure or satisfaction, the need to alleviate a nicotine-induced drive state and a stimulus-driven impulse potentially play an important role. This study aimed to provide a preliminary assessment of how far urges to smoke are reported by smokers and whether the strength of such urges prior to a quit attempt predicts short-term success at quitting. In a prospective study, 566 smokers attending a treatment programme to help smokers quit completed a written questionnaire covering frequency of different types of urge to smoke (automatic impulse - 'automatic urges', anticipated pleasure - 'pleasure urges', and fulfilling a need - 'need urges'). They were asked to rate this for whichever of these urges was dominant for them. The questionnaire also assessed daily cigarette consumption, time to first cigarette of the day, age and gender. Carbon monoxide verified smoking status was recorded at 1 and 4weeks after the target quit date. A total of 47.9% (271) of smokers reported that automatic urges were dominant, 21.7% (123) reported pleasure urges to be dominant, and 30.4% (172) reported need urges to be dominant. The strength of automatic urges predicted abstinence at both 1week (OR=0.74, p=0.005, 95%CI=0.60-0.92) and 4weeks (OR=0.73, p=0.008, 95%CI=0.59-0.92). Associations between other urge types and abstinence were not statistically significant. A substantial proportion of smokers attending a clinic for help with quitting report that their dominant urges to smoke occur without any anticipation of pleasure or relief and the strength of the automatic urges predicts failure to sustain abstinence following a quit attempt. Copyright © 2017. Published by Elsevier Ltd.

  19. Revascularização miocárdica de urgência após complicação de angioplastia transluminal coronária: abordagem cirúrgica atual Emergency myocardial revascularization after complicated percutaneous transluminal coronary angioplasty: actual surgical approach

    Directory of Open Access Journals (Sweden)

    Luís Alberto Dallan

    1990-04-01

    Full Text Available Entre julho de 1981 e fevereiro de 1990, foram realizados no INCOR 3016 angioplastias transluminais coronárias (ATC, em 2431 pacientes portadores de insuficiência coronária em suas diferentes manifestações. A cirurgia de revascularizaçâo do miocárdio de urgência foi necessária em 79 (3,2% desses pacientes, dos quais 32 (40,5% infartaram e 12 (15,2% faleceram. Dos 1530 pacientes submetidos estivamente a ATC por angina estável, 11,9% (7/59 faleceram no intra ou no pós-operatório. Dentre os 112 pacientes em que a ATC foi realizada de urgência devido a angina instável, 18,2% (2/11 evoluíram para óbito operatório. Nos 789 já infartados previamente à ATC, a mortalidade cirúrgica foi de 33,3% (3/9. A análise estatística demonstrou mortalidade mais elevada em pacientes idosos, em pacientes com dissecção do tronco da artéria coronária esquerda ou trombose coronária tardia e, especialmente, naqueles com instabilidade hemodinâmica após a ATC. O tempo decorrido entre a complicação da ATC e a revascularizaçâo do miocárdio também constitui fator agravante no prognóstico. O número de cirurgias de urgência após ATC diminuiu significativamente nos últimos dois anos (10/1351, a despeito do grau progressivo de complexidade das lesões dilatadas. O emprego de balões com extremidade atraumática e, especialmente, de cateter de reperíusão (Stack, que mantém o fluxo coronário mesmo diante do desprendimento da placa ateromatosa, contribuiu, decisivamente, para esses resultados. As modificações introduzidas na sistematização operatória, principalmente o uso de cardioplegia sangüínea com indução normotérmica e administrada por vias anterógrada e retrógrada, também propiciaram melhores resultados cirúrgicos. A associação desses procedimentos vem se mostrando benéfica, não tendo sido observados óbitos nos últimos 14 meses.Between July 1981 and February 1990, 2431 patients underwent attempted percutaneous

  20. Avaliação inicial do Serviço de Atendimento Móvel de Urgência na Cidade de Porto Alegre

    Directory of Open Access Journals (Sweden)

    Gladis Semensato

    2011-03-01

    Full Text Available FUNDAMENTO: Os Serviços de Atendimento Móvel de Urgência (SAMU no Brasil têm resultados imediatos pouco conhecidos. OBJETIVO: Avaliar os preditores clínicos de sobrevida dos pacientes em parada cardiorrespiratória (PCR no ambiente não hospitalar atendidos pelo SAMU de Porto Alegre. MÉTODOS: Estudo observacional e prospectivo. Os desfechos avaliados foram sobrevida em 30 dias e até a alta hospitalar, além de escore do Cerebral Performance Category (CPC I-II. RESULTADOS: De janeiro a outubro de 2008, foram atendidos 593 pacientes em PCR não traumática e foram realizadas 260 tentativas de ressuscitação cardiopulmonar (RCP. Houve sucesso inicial em 52 (20,0% casos, estando 16 pacientes vivos no 30º (6,0% dia, 10 tendo recebido alta hospitalar (3,9%, sendo que 6 (2,3% com escore CPC I-II. A PCR no domicílio associou-se inversamente com a sobrevida no 30º dia (p = 0,001 e na alta hospitalar (p = 0,02. Um ritmo inicial "chocável" (p = 0,008 associou-se à sobrevida aos 30 dias. O intervalo tempo-resposta e tempo colapso até início da RCP foram significativamente menores em sobreviventes aos 30 dias. Em análise multivariada, foram preditores independentes de mortalidade aos 30 dias um ritmo inicial chocável (razão de chance [RC] = 0,28 e intervalo de confiança [IC] de 95,0% = 0,10 - 0,81; p = 0,02 e PCR no domicílio (RC = 3,0 e IC 95,0% = 1,04 - 8,7; p = 0,04. CONCLUSÃO: O atendimento pré-hospitalar da PCR em Porto Alegre tem resultados limitados, porém equiparáveis a outras localidades internacionais. É necessário o reforço de cada elo da corrente da sobrevivência para aperfeiçoar o atendimento pré-hospitalar, visando melhora de resultados clinicamente relevantes.

  1. Perfil dos atendimentos realizados por uma unidade de suporte avançado do serviço de atendimento móvel de urgência (SAMU do Rio Grande do Sul = Profile of attendances made by an advanced support unit from the mobile emergency care service (MECS of Rio Grande do Sul state, Brazil

    Directory of Open Access Journals (Sweden)

    Casagrande, Denise

    2013-01-01

    Conclusões: Os atendimentos realizados pela Unidade de Suporte Avançado do Serviço de Atendimento Móvel de Urgência da cidade de Ijuí incluíram predominantemente homens entre 60 e 79 anos acometidos por doenças crônico-degenerativas. Os procedimentos realizados com maior frequência foram os de suporte básico de vida. Estes resultados devem direcionar a atualização dos profissionais e a organização dos serviços móveis de emergência

  2. Integrated management system: expedience and organizational aspects

    Directory of Open Access Journals (Sweden)

    Trunova Ekaterina Viktorovna

    2011-06-01

    Full Text Available The correctly lined up management system is an important element of intellectual capital of company and promotes growth of its market value. In the article grounded, that realization of strategy is impossible without intercommunication of strategic management and business-process management. Such organizational aspects of administrative activity, as role conception of management, strategic office and process office, are observed.

  3. Sophia: A Expedient UMLS Concept Extraction Annotator.

    Science.gov (United States)

    Divita, Guy; Zeng, Qing T; Gundlapalli, Adi V; Duvall, Scott; Nebeker, Jonathan; Samore, Matthew H

    2014-01-01

    An opportunity exists for meaningful concept extraction and indexing from large corpora of clinical notes in the Veterans Affairs (VA) electronic medical record. Currently available tools such as MetaMap, cTAKES and HITex do not scale up to address this big data need. Sophia, a rapid UMLS concept extraction annotator was developed to fulfill a mandate and address extraction where high throughput is needed while preserving performance. We report on the development, testing and benchmarking of Sophia against MetaMap and cTAKEs. Sophia demonstrated improved performance on recall as compared to cTAKES and MetaMap (0.71 vs 0.66 and 0.38). The overall f-score was similar to cTAKES and an improvement over MetaMap (0.53 vs 0.57 and 0.43). With regard to speed of processing records, we noted Sophia to be several fold faster than cTAKES and the scaled-out MetaMap service. Sophia offers a viable alternative for high-throughput information extraction tasks.

  4. Expedient Gap Definition Using 3D LADAR

    National Research Council Canada - National Science Library

    Edwards, Lulu; Jersey, Sarah R

    2006-01-01

    .... Army Engineer Research and Development Center (ERDC), ASI has developed an algorithm to reduce the 3D point cloud acquired with the LADAR system into sets of 2D profiles that describe the terrain...

  5. Expedient Gap Definition Using 3D LADAR

    Science.gov (United States)

    2006-09-01

    Research and Development Center (ERDC), ASI has developed an algorithm to reduce the 3D point cloud acquired with the LADAR system into sets of 2D...ATO IV.GC.2004.02. The GAP Program is conducted by the U.S. Army Engineer Research and Development Center (ERDC) in conjunction with the U.S. Army...Introduction 1 1 Introduction Background The Battlespace Gap Definition and Defeat ( GAP ) Program is conducted by the U.S. Army Engineer Research and

  6. Expedient Approaches for the Management of Wastes ...

    Science.gov (United States)

    Report The current study sought to determine waste decontamination conditions that would achieve complete kill for all material types. For these tests, more stringent decontamination procedures were evaluated specifically using pAB amended with a surfactant and/or waste submersion procedures involving agitation.

  7. ASAS KEPASTIAN HUKUM, KEADILAN DAN KEMANFAATAN DALAM KAITANNYA DENGAN PUTUSAN KEPAILITAN PENGADILAN NIAGA

    Directory of Open Access Journals (Sweden)

    Tata Wijayanta

    2014-05-01

    Full Text Available The principles of legal assurance, justice and expediency are properly stipulated in the provisions of the Act Number 37 Year 2004.  The legal assurance is seen by the rapidity of the settlement and the expeditious evidentiary procedure. The justice is reflected in equality principle in the proceeding. Then, the expediency is conceived from the imposition of bankruptcy as the last resort (ultimum remidium and the application of open to public-trial. Nevertheless, in certain case laws from the Commercial Court, the principles were not applied harmoniously.  The legal assurance appears to be more emphasized than the other principles. Take for example the bankruptcy case of PT Telekomu-nikasi Phones (District-Commercial Court of Central Jakarta Number: 48/Bankruptcy/2012/PN Nia-ga.Jkt.Pst that has been reviewed and nullified by the Supreme Court Number: 704K/Pdt.Sus/ 2012. Key words:  legal certainty, justice, expediency, bankruptcy decision.

  8. A prática oceanográfica e a coleção iconográfica do rei dom Carlos I

    Directory of Open Access Journals (Sweden)

    Maria Estela Jardim

    2014-09-01

    Full Text Available Após a expedição do Challenger (1872-1878, outras nações começaram a interessar-se pela pesquisa oceanográfica e a organizar suas próprias expedições. Desde 1885 que o príncipe Albert I de Mónaco realizava campanhas oceanográficas, com a colaboração de alguns dos melhores cientistas em biologia marinha e em oceanografia física, inventando técnicas e instrumentos para a realização dos trabalhos oceanográficos. A atividade científica do príncipe Albert certamente contribuiu para estimular o interesse do seu amigo, o rei dom Carlos I de Portugal, pelo estudo dos oceanos e da vida marinha. Ambos compartilhavam a necessidade de usar a fotografia para documentar suas pesquisas. Este artigo analisa o papel da fotografia científica na ciência oceanográfica, particularmente nas expedições realizadas pelo monarca português.

  9. "... Urged by His Wife Jezebel"

    DEFF Research Database (Denmark)

    Holt, Else Kragelund

    1995-01-01

    The narrative 1 Kgs 18 of Elijah's battle on M. Carmel with the Baalpriests can be viewed as yet another OT story of the appointment of the scapegoat. Using R. Girard's methdology it appears that the Baalpriests are held responsible for the drougth, and are slaughtered as a kind of sacrifice. Her...

  10. HUGO urges genetic benefit-sharing.

    Science.gov (United States)

    2000-01-01

    In view of the fact that for-profit enterprise exceeds public expenditures on genetic research and that benefits from the Human Genome Project may accrue only to rich people in rich nations, the HUGO Ethics Committee discussed the necessity of benefit-sharing. Discussions involved case examples ranging from single-gene to multi-factorial disorders and included the difficulties of defining community, especially when multifactorial diseases are involved. The Committee discussed arguments for benefit-sharing, including common heritage, the genome as a common resource, and three types of justice: compensatory, procedural, and distributive. The Committee also discussed the importance of community participation in defining benefit, agreed that companies involved in health have special obligations beyond paying taxes, and recommended they devote 1-3% of net profits to healthcare infrastructure or humanitarian efforts.

  11. New laws on population urged.

    Science.gov (United States)

    1976-12-03

    A workshop on ''Population and the Law'' sponsored by the Family Planning Organization of the Philippines and the International Planned Parenthood Federation recommended the following changes in Philippine law to implement family planning: legalization of abortion for women whose life or health are endangered by pregnancy and those who become pregnant despite contraceptives; delaying age of marriage to 18; extension of family planning incentives and maternity leave to women in government service; allow trained nurses and midwives to dispense contractives; legalize sterilization; include sterilization in medicare benefits; specify by law which contraceptive drugs may be dispensed by nonphysicians and nonpharmacists in rural areas; legalize premarital family planning counseling; declare family planning materials tax exempt; encourage reluctant doctors to practice sterilization through professional regulatory agencies; extend industrial family planning services to women living near the plant; launch massive information drives to advise young people of the hazards of premarital sex; strict enforcement of abortion laws in areas where illegal abortion still exists; grant women equal rights in area of consent for sterilization; and eliminate the stigma of illegitimacy for those born out of wedlock.

  12. Toward bridging the gap between biological, psychobiological and psychosocial models of alcohol craving.

    Science.gov (United States)

    Monti, P M; Rohsenow, D J; Hutchison, K E

    2000-08-01

    Urge to drink ("craving") has been a central focus of many theories and treatments, but some researchers question the importance of urges during recovery. Several studies assessed reactions to the presence of beverage alcohol (cue-reactivity) or to simulated high-risk situations (role plays). Higher urges in response to role plays predicted more drinking during the 6 months after treatment. However, urges in response to beverage cues were inconsistently predictive of outcome while measures of awareness or attention to cues predicted less drinking. Urge to drink might reflect a conflict between motivation to drink and awareness of danger. Whether urges predict increased risk of drinking should be a function of factors that affect motivation to drink, awareness of risk and effectiveness of coping. Cue-reactivity assessment has recently been used to bridge the gap between psychosocial and biomedical approaches in several ways: (1) salivation to cues predicts increased drinking independent of urge or attention, showing the value of including both physiological and psychosocial measures; (2) naltrexone has been shown to decrease cue-elicited urge to drink, illustrating the value of this assessment methodology for medications evaluation and (3) pre-pulse inhibition of startle response is being used to investigate the role of dopaminergic pathways in cue-elicited urge. Thus, this laboratory based program of research has the potential to add to knowledge of both biomedical and psychosocial mechanisms involved in urge and relapse, leading to greater integration of models.

  13. Principais achados de colonoscopias realizadas em caráter de urgência e eletivas Main finding on emergency and electie colonoscopies

    Directory of Open Access Journals (Sweden)

    Carlos Henrique Marques dos Santos

    2009-03-01

    Full Text Available Desde 1960 houve grande avanço tecnológico na observação do aparelho digestivo com o advento dos endoscópios flexíveis, usados inicialmente para o trato digestivo superior e posteriormente também para o inferior, permitindo diagnósticos mais precisos e realização do tratamento em alguns casos. Mesmo em situações de urgência a colonoscopia pode ser utilizada como primeira escolha podendo ser diagnóstica e terapêutica. OBJETIVO: O presente estudo teve por objetivo avaliar quais foram os resultados principais das colonoscopias realizadas no Setor de Endoscopia Digestiva do Hospital Regional de Mato Grosso do Sul. MATERIAIS E MÉTODOS: Foram estudados 290 pacientes submetidos à colonoscopia no Serviço de Endoscopia Digestiva do Hospital Regional do Mato Grosso do Sul, no período de novembro de 2006 a agosto de 2007. Foram analisadas as seguintes variáveis: sexo, idade, caráter de indicação do exame (urgência e eletiva e diagnóstico. RESULTADOS: A idade média foi de 52 anos, variando de 15 a 92 anos. A maioria dos pacientes era do sexo feminino (56,5%. Dos 290 exames realizados no período foram constatados 48,5% (n=141 de colonoscopias com diagnóstico normal. Dentre os anormais houve uma prevalência de doença diverticular dos colos (n=56, seguido de pólipos (n=37, doenças inflamatórias (n=31, neoplasias (n=18 e angiodisplasia (n=7. Os pólipos apresentaram uma maior concentração em colo sigmóide (n=18 seguido pelo colo descendente e reto. As doenças inflamatórias apresentaram como diagnóstico colonoscópio, colite actínica (n=11 seguida por retite actínica (n=7 e retite inespecífica (n=7. Houve um maior número de procedimentos oriundos do ambulatório (73% em contraste com internados (20% e provenientes do Pronto Socorro (7%. CONCLUSÃO: A doença diverticular e os pólipos foram os diagnósticos preponderantes, pois a maior indicação foi a hemorragia digestiva. Uma alta incidência de pólipos em sigm

  14. Psychiatric Diagnosis and Criminal Record Determine the Courts’ Decisions

    DEFF Research Database (Denmark)

    Kørner, Ejnar Alex; Gottlieb, Peter; Gabrielsen, Gorm

    2014-01-01

    Section 69 of the Danish Penal Code implies the possibility of sentencing also non-psychotic offenders to treatment when this is considered expedient. The aim of this study was to analyse which factors influence the courts’ decisions to sentence offenders to psychiatric treatment instead of punis......Section 69 of the Danish Penal Code implies the possibility of sentencing also non-psychotic offenders to treatment when this is considered expedient. The aim of this study was to analyse which factors influence the courts’ decisions to sentence offenders to psychiatric treatment instead...

  15. Economic Efficiency of Establishing Domestic Production of Synthetic Liquid Fuel

    Directory of Open Access Journals (Sweden)

    Kyzym Mykola O.

    2017-06-01

    Full Text Available The article notes a stable tendency to increasing the oil dependence of Ukraine, which creates a threat to the national economic security, and proves an expediency of establishing domestic production of synthetic liquid fuel. The technical, organizational and economic features of establishing synthetic liquid fuel production in Ukraine are presented. There proved a hypothesis on the expediency of organizing the production of synthetic liquid fuels based on steam-plasma coal gasification technology. The forecast resource cycle of the country until 2020 under conditions of developing this technology is modeled.

  16. Violência doméstica e familiar contra a mulher: estudo de casos e controles com vítimas atendidas em serviços de urgência e emergência

    Directory of Open Access Journals (Sweden)

    Leila Posenato Garcia

    2016-01-01

    Full Text Available O objetivo deste estudo foi identificar fatores associados ao atendimento por violência doméstica e familiar entre vítimas atendidas em serviços de urgência e emergência no Brasil. Realizou-se estudo de casos e controles baseado no Sistema de Vigilância de Violências e Acidentes (VIVA, 2011. Foram selecionadas mulheres com 18 anos ou mais de idade, vítimas de violência doméstica e familiar (casos em comparação com aquelas vítimas de acidentes (controles. As razões de chances ajustadas foram estimadas por regressão logística não condicional. Foram incluídos 623 casos e 10.120 controles. Na análise ajustada, foram fatores de risco: idade mais jovem (18-29 anos, baixa escolaridade, não exercer atividade remunerada, consumo de bebida alcoólica, procura de atendimento em outro serviço, ocorrência em final de semana e durante a noite ou madrugada. A violência doméstica e familiar teve o consumo de bebida alcoólica como fator fortemente associado. Os dias e horas de maior ocorrência evidenciam a necessidade de adequação dos serviços de atendimento às vítimas.

  17. LOCATING THE TRAILING EDGE OF THE CIRCUMBINARY RING IN THE KH 15D SYSTEM

    International Nuclear Information System (INIS)

    Capelo, Holly L.; Herbst, William; Leggett, S. K.; Hamilton, Catrina M.; Johnson, John A.

    2012-01-01

    Following two years of complete occultation of both stars in the binary T Tauri star KH 15D by its opaque circumbinary ring, KH 15D has abruptly brightened again during apastron phases, reaching I = 15 mag. Here, we show that the brightening is accompanied by a change in spectral class from K6/K7 (the spectral class of star A) to ∼K1, and a bluing of the system in V – I by about 0.3 mag. A radial velocity measurement confirms that, at apastron, we are now seeing direct light from star B, which is more luminous and of earlier spectral class than star A. Evidently, the trailing edge of the occulting screen has just become tangent to one anse of star B's projected orbit. This confirms a prediction of the precession models, supports the view that the tilted ring is self-gravitating, and ushers in a new era of the system's evolution that should be accompanied by the same kind of dramatic phenomena observed from 1995 to 2009. It also promotes KH 15D from a single-lined to a double-lined eclipsing binary, greatly enhancing its value for testing pre-main-sequence models. The results of our study strengthen the case for truncation of the outer ring at around 4 AU by a sub-stellar object such as an extremely young giant planet. The system is currently at an optimal configuration for detecting the putative planet and we urge expedient follow-up observations.

  18. Acute effects of brisk walking on sugary snack cravings in overweight people, affect and responses to a manipulated stress situation and to a sugary snack cue: a crossover study.

    Science.gov (United States)

    Ledochowski, Larissa; Ruedl, Gerhard; Taylor, Adrian H; Kopp, Martin

    2015-01-01

    Research has shown that acute exercise reduces urges for chocolate in normal weight people. This study aimed to examine the effects of an acute exercise bout on urges to consume sugary snacks, affect as well as 'psychological and physiological responses' to stress and a 'sugary snack cue', in overweight individuals. Following 3 days of chocolate-abstinence, 47 overweight, sugary snack consumers were assessed, in 2 randomly ordered conditions, in a within-subject design: 15-min brisk walk or passive control. Following each, participants completed 2 tasks: Stroop color-word interference task, and handling sugary snacks. Urges for sugary snacks, affective activation and valence were assessed. ANOVAs revealed significant condition x time interaction effects for: urges to consume sugary snacks, affective valence and activation. Obtained data show that exercise reduces urges for sugary snacks and attenuates urges in response to the stress situation and the cue in overweight people.

  19. Acute effects of brisk walking on sugary snack cravings in overweight people, affect and responses to a manipulated stress situation and to a sugary snack cue: a crossover study.

    Directory of Open Access Journals (Sweden)

    Larissa Ledochowski

    Full Text Available Research has shown that acute exercise reduces urges for chocolate in normal weight people. This study aimed to examine the effects of an acute exercise bout on urges to consume sugary snacks, affect as well as 'psychological and physiological responses' to stress and a 'sugary snack cue', in overweight individuals. Following 3 days of chocolate-abstinence, 47 overweight, sugary snack consumers were assessed, in 2 randomly ordered conditions, in a within-subject design: 15-min brisk walk or passive control. Following each, participants completed 2 tasks: Stroop color-word interference task, and handling sugary snacks. Urges for sugary snacks, affective activation and valence were assessed. ANOVAs revealed significant condition x time interaction effects for: urges to consume sugary snacks, affective valence and activation. Obtained data show that exercise reduces urges for sugary snacks and attenuates urges in response to the stress situation and the cue in overweight people.

  20. Nuclear war survival skills

    International Nuclear Information System (INIS)

    Kearny, C.H.

    1982-01-01

    This book brings together field-tested instructions that, if followed by a large fraction of Americans during a crisis that preceded an attack, could save millions of lives. Myths and facts about consequences of a massive nuclear attack are discussed. The main emphasis, however, is on preparations that could be made in the last few days of a worsening crisis. This book includes chapters on psychological preparations, warning and communications, and evacuation. These chapters describe the building of expedient shelters, their ventilation and cooling, the purification and storage of adequate water, the processing and cooking of whole grains and legumes, fallout meters, protection against fires and carbon monoxide, and expedient furnishings for shelters. Other chapters cover sanitation and preventive medicine, medical advice for nuclear survivors lacking the help of doctors, improvised footwear and clothing, and advice on minimum preparations that can be made at low cost and should be made before a crisis arises. One appendix gives detailed, field-tested instructions for building six types of earth-covered expedient fallout shelters, with criteria to guide the choice of which shelter to build. The design features of several types of expedient blast shelters are described in another appendix. Two others contain instructions for making an efficient shelter-ventilating pump and a homemade fallout meter that is accurate and dependable using inexpensive materials found in most households. The report is primarily a compilation and summary of civil defense measures and inventions developed at ORNL over the past 14 years and field-tested in six states, from Florida to Utah, for use by untrained citizens

  1. Human performance evaluation: The procedures of ultimate response guideline for nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Kang-Hung, E-mail: alvinks@iner.gov.tw [Institute of Nuclear Energy Research, Atomic Engery Council, No. 1000, Whenhua Road, Jiaan Village, Longtan Township, Taoyuan County, Taiwan (China); Hwang, Sheue-Ling, E-mail: slhwang@ie.nthu.edu.tw [Department of Industrial Engineering and Engineering Management, National Tsing Hua University, No. 101, Section 2, Kuang-Fu Road, Hsinchu, Taiwan 30013, Taiwan (China)

    2014-07-01

    Highlights: • This study adopts SPAR-H to evaluate HEPs in the URG procedures. • The involvement of URG procedures could reduce CDF significantly. • Upgrading the training level of staff will enhance the reliability effectively. • Aiding the plant manager in making URG decision will enhance the reliability. - Abstract: In the nuclear accident which occurred in Japan on March 11, 2011, several units of Fukushima conventional BWR experienced a total loss of power and water supply triggered by a heavy earthquake and subsequent Tsunami which were outside design models. In the past, when an accident occurred, operators in nuclear power plants (NPP) followed emergency operating procedures (EOPs) or severe accident management guidance (SAMG). However, EOP and SAMG are symptom-based procedures to cope with severe transients and accidents, depending on real-time operational parameters. Ultimate response guidelines (URG), a plant specific interim remedy action plan, was developed to manage accidents caused by compound disasters which exceed design models. The URG guides the plant operators’ conduct of reactor depressurization, core cooling water injection, and containment venting. This study adopts NUREG/CR-6883 (Standardized Plant Analysis Risk Human Reliability Analysis, SPAR-H) to evaluate human error probabilities (HEPs) of action and diagnosis in the current URG procedures. We found the human reliability of URG procedures analyzed by SPAR-H is about 85% (depending on different decision makers). Upgrading the training level of staff or enhancing plant managers ability to decide whether to execute URG will enhance the human reliability of URG procedures.

  2. Atendimentos de jovens vítimas de agressões em serviços públicos de urgência e emergência, 2011: diferenças entre sexos

    Directory of Open Access Journals (Sweden)

    Alice Cristina Medeiros Melo

    Full Text Available Resumo O objetivo deste artigo é descrever as características das agressões entre jovens vítimas de violências atendidos em serviços de urgência e emergência, segundo sexos. Trata-se de estudo descritivo com dados do Sistema de Vigilância de Violências e Acidentes do Ministério da Saúde, realizado em 71 serviços localizados em 24 capitais brasileiras e no Distrito Federal, em 2011. Indivíduos do sexo masculino predominaram entre as vítimas (75,1% e entre os agressores (83,1% e 69,7% dos casos de violência perpetrada contra vítimas do sexo masculino e feminino, respectivamente. Entre vítimas do sexo feminino, predominaram ocorrências no domicílio (43,6%. O agressor era um estranho em 49,7% dos casos entre vítimas dos sexos masculino e 26,8% do sexo feminino, enquanto era um parceiro ou ex-parceiro em 3,9% e 31,5% (p < 0,001. A maior gravidade das lesões entre os homens era consistente com a maior proporção de mortes nas primeiras 24 horas (2,1% em comparação com as mulheres (0,2% (p < 0,001. As características das agressões entre vítimas jovens revelaram-se substancialmente diferentes segundo o sexo. É evidenciada a necessidade da implementação de políticas públicas intersetoriais voltadas para a prevenção da violência, conforme previsto no Estatuto da Juventude.

  3. Acidentes perfurocortantes e medidas preventivas para hepatite B adotadas por profissionais de Enfermagem nos serviços de urgência e emergência de Teresina, Piauí

    Directory of Open Access Journals (Sweden)

    Telma Maria Evangelista de Araújo

    Full Text Available Objetivos analisar a ocorrência de acidentes perfurocortantes e as medidas preventivas associadas à hepatite B entre profissionais de Enfermagem em serviços de urgência e emergência. Métodos estudo transversal analítico com aplicação de questionário a 317 participantes de cinco hospitais públicos de Teresina, PI, em 2010. Resultados 152 (47,9% referiram ter sofrido acidente perfurocortante; entre as categorias, 27,3% dos Enfermeiros, 48,2% dos Auxiliares, 52,6% dos Técnicos de Enfermagem. A chance de um profissional de nível médio (Auxiliar ou Técnico sofrer um acidente perfurocortante é de 2,8 (1,38-5,67 vezes maior que o de nível superior (Enfermeiros. A agulha foi o instrumento causador mais frequente (77,0%. A não notificação do acidente foi expressiva entre Técnicos (67,0%, Auxiliares (70,0% e Enfermeiros (75,0%, assim como a não adoção de medidas profiláticas pós-exposição (84,9%, em média. As três categorias profissionais referiram uso de luvas como o EPI mais utilizado. Os Auxiliares de Enfermagem apresentaram o menor percentual (47,0% de esquema vacinal completo para hepatite B. Discussão um percentual expressivo de profissionais de Enfermagem sofreu acidente perfurocortante no trabalho com baixa adoção de medidas preventivas e profiláticas, reforçando a necessidade de fortalecimento de estratégias que visem à saúde do trabalhador no âmbito hospitalar.

  4. Field Expedient Armor Modifications to US Armored Vehicles

    Science.gov (United States)

    2006-06-01

    Report on US vs. German Armor,” Exhibit 3, p. 42. 37Ibid., Exhibit 2, p. 38. 38Kenneth W. Estes, Marines Under Armor , The Marine Corps and the...Washington, D.C., 1945), 62. 43Estes, Marines Under Armor , 81. 44Ibid. 45Cameron, “Armor Combat Development 1917-1945,” 17. 46Mayo, The Technical...Marines Under Armor , 53. 72William E. Bennett, Charles W. Fletcher, French G. Lewis, Gerald H. Shea, Rufus J. Cleghorn, James F. Beaver and Thomas

  5. Evaluation of Expedient Surfaces for Remote Piloted Aircraft

    Science.gov (United States)

    2017-12-01

    left half-panels. These are identical in dimensions and weight, but the ERDC/GSL TR-17-27 5 locations of the welded aluminum blocks are...to fit a double-arrow locking key that could be inserted once panels were placed next to each other on the ground. The connection along the long edge...surface of panels (b) Locking key (c) Stack of panels as delivered (d) End connector Table 2.3. Items delivered for installing the PSA-FT

  6. A probabilistics safety assessment of ultimate response guidelines of Maanshan Nuclear Power Plant

    Energy Technology Data Exchange (ETDEWEB)

    Wang, P-Y.; Lee, M. [National Tsing Hua Univ., Hsinchu, Taiwan (China); Chao, C-C. [Inst. of Nuclear Energy Research, Taoyuan, Taiwan (China)

    2014-07-01

    Ultimate Response Guidelines (URGs) was proposed to mitigate the so called 'Fukushima type accident' of nuclear power plants (NPPs). As specified in URGs, if it is necessary, operators will depressurize the secondary side of steam generators (SGs) to bring in the low pressure water. The injection damages the economic value of the plant. However, the injection prevents the cladding temperature from rising above 1500 F (1089 K), which is the temperature that release of volatile fission products from gap is initiated. In the present study, the impact of URGs on the Core Damage Frequency (CDF) in a SBO (Station Blackout) accident of a Pressurized Water Reactor (PWR) designed by Westinghouse and adopts large dry containment is quantified. In the Base Case analysis of the study, the actions in the URGs are not considered. The CDF of SBO in the base case calculation is 2.49x10{sup -7} year. The actions specified in URGs can reduce CDF by 62%. The strategies in URGs are very effective in enhancing the reliability of decay heat removal via SG secondary side. Therefore, the implementation of these strategies can reduce the CDF of sequences involving late failure of AFWS. After the incorporation URGs, the dominant sequences of SBO are the sequences with seal failure. (author)

  7. Spatial variations of earthquake occurrence and coseismic deformation in the Upper Rhine Graben, Central Europe

    Science.gov (United States)

    Barth, A.; Ritter, J. R. R.; Wenzel, F.

    2015-05-01

    Seismic activity in the densely populated Upper Rhine Graben (URG) is an aspect in the public, political, and industrial decision making process. The spatial analysis of magnitude-frequency distributions provides valuable information about local seismicity patterns and regional seismic hazard assessment and can be used also as a proxy for coseismic deformation to explore the seismo-tectonic setting of the URG. We combine five instrumental and one historic earthquake bulletins to obtain for the first time a consistent database for events with local magnitudes ML ≥ 2.0 in the whole URG and use it for the determination of magnitude frequencies. The data processing results in a dataset with 274 Poisson distributed instrumentally recorded earthquakes within the URG between 01/1971 and 02/2012 and 34 historic events since the year 1250. Our analysis reveals significant b-value variations along the URG that allow us to differentiate four distinct sections (I-IV) with significant differences in earthquake magnitude distributions: I: Basel region in the Swiss-France-German border region (b = 0.83), II: region between Mulhouse and Freiburg in the southern URG (b = 1.42), III: central URG (b = 0.93), and IV: northern URG (b = 1.06). High b-values and thus a relatively low amount of high magnitude events in the Freiburg section are possibly a consequence of strongly segmented, small-scale structures that are not able to accumulate high stresses. We use the obtained magnitude-frequency distributions and representative source mechanisms for each section to determine coseismic displacement rates. A maximum horizontal displacement rate of 41 μm/a around Basel is found whereas only 8 μm/a are derived for the central and northern URG. A comparison with geodetic and geological constraints implies that the coseismic displacement rates cover less than 10% of the overall displacement rates, suggesting a high amount of aseismic deformation in the URG.

  8. Rimsevics urges state to boost exports

    Index Scriptorium Estoniae

    2008-01-01

    Läti Panga president Ilmars Rimsevics õhutab Läti äriliidreid ja valitsusjuhte restruktureerima investeeringud ning edendama eksporti. Maailmamajanduse langus pole veel mõjutanud nõudmist Läti ekspordile

  9. Baltic PMs urge support for EU

    Index Scriptorium Estoniae

    2003-01-01

    Eesti peaministri Juhan Partsi, Läti peaministri Einars Repshe ja Leedu peaministri Algirdas Brazauskase ühisavaldusest Eestile ning Lätile järgimaks Leedu eeskuju referendumil EL-i poolt hääletamises

  10. Will the urge to merge continue?

    International Nuclear Information System (INIS)

    Gobert, W.A.

    2001-01-01

    A review of oil and gas markets was presented along with mergers and acquisitions activity. The objective of the exercise was to determine if the current trend of mergers within the oil industry will continue. The review of oil and gas markets included a historical look at crude oil and natural gas prices as well as on industry activity as a whole. A series of economic indicator graphs demonstrate that buyers wallets are full, oil and gas prices have beat the estimates, purchase prices have inflated and shareholders continue to sell at a discount. This information has led the author to conclude that the trend to merge will definitely continue. 2 tabs., 18 figs

  11. Ilves urges global unity / Ella Karapetyan

    Index Scriptorium Estoniae

    Karapetyan, Ella

    2010-01-01

    President Toomas Henrik Ilves rääkis ÜRO Peaassambleel New Yorgis 24. septembril 2010 peetud kõnes Eesti abist Afganistanile, inimõigustest, küberkuritegevusest ja kinnitas Eesti toetust Gruusiale. Töövisiit Ameerika Ühendriikidesse 20.-27.09.2010

  12. Revamp urged for Norway's offshore regime

    International Nuclear Information System (INIS)

    Anon.

    1991-01-01

    This paper reports that the Norwegian government has come under renewed pressure from offshore operators to fine tune its licensing procedures and tax regime. The need for change was emphasized at the Advanced Petroleum Conference in Stavanger attended by senior personnel from companies active in the Norwegian and British sectors of the North Sea. Companies have had some success in the tax front, winning changes in proposals from Norway's Ministry of Finance for offshore tax reform. The changes were required to offset a general reduction in the corporate tax to 28% from 50.8%. Norsk Shell has told the government that in view of uncertainty about taxes it will not take part in the normal industry-government discussions about what acreage should be included in the 14th licensing round to be announced next year. This action does not bar Shell from participating in the licensing round when it gets under way. Shell has the if the tax package is not changed sharply in its passage through Storting it is unlikely to bid for new licenses

  13. The ultimate response guideline simulation and analysis by using (TRACE) for Lungmen ABWR nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Hao-Tzu [Atomic Energy Council, Inst. of Nuclear Energy Research, Taoyuan City, Taiwan (China); Yang, Shu-Ming; Chen, Shao-Wen; Wang, Jong-Rong; Shih, Chunkuan [National Tsing Hua Univ., Inst. of Nuclear Engineering and Science, HsinChu, Taiwan (China)

    2015-07-15

    In this research, the TRACE/SNAP model of Lungmen ABWR nuclear power plant (NPP) has been established for the simulation and analysis of ultimate response guideline (URG). The main actions of URG are depressurization and low pressure water injection of reactor and containment venting. This research focuses to assess the URG utility of Lungmen NPP under Fukushima-like conditions. This study consists of three steps. The first step is the establishment of Lungmen NPP TRACE/SNAP model. In order to evaluate the system response of TRACE/SNAP model, FSAR data (MSIV closure and loss of feedwater flow transient) were used to compare with the results of TRACE. The second step is the URG simulation and analysis under Fukushima-like conditions by using Lungmen NPP TRACE/SNAP model. In this step, the no URG case was also performed in order to evaluate the URG effectiveness of Lungmen NPP. In order to confirm the mechanical property and integrity of fuel rods, the final step is FRAPTRAN analysis. According to TRACE analysis results, the URG can keep the peak cladding temperature (PCT) below the criteria 1088.7 K under Fukushima-like conditions which indicates that Lungmen NPP can be controlled in a safe situation. Nevertheless, if Lungmen NPP does not perform the URG under Fukushima-like conditions, the water level may drop lower than TAF after 1100 s which means a safety issue about the fuel rods may be generated. The analysis results of FRAPTRAN also indicate the integrity of fuel rods cannot be kept under the above conditions.

  14. Greener Alternatives to Expedient Synthesis of Heterocycles and Nanomaterial

    Science.gov (United States)

    A brief account of reactions involving microwave (MW) exposure of neat reactants or catalyzed by mineral support surfaces, such as alumina, silica, clay, or their ‘doped’ versions, for the rapid one-pot assembly of heterocyclic compounds [1] from in situ generated reactive interm...

  15. An Expedient Method for the Synthesis of Acylhydrazones under ...

    African Journals Online (AJOL)

    NJD

    important class of heterocyclic compounds with a wide a range of pharmaceutical and biological activities.16–18. Usually, the synthetic method to produce acylhydrazones involves the reaction between acylhydrazides and aldehydes in ethanol at reflux temperature for about 2–3 hours, the solvent is then concentrated, the ...

  16. Evaluation of Expedient Methods for Mitigating Dust on Helipads

    National Research Council Canada - National Science Library

    Tingle, Jeb

    2004-01-01

    ...) and one for sustainment use on roads and other large area applications. The project consisted of the evaluation of various dust palliatives and application equipment under controlled laboratory conditions and during field tests...

  17. Animals in nuclear research: where ethics and expediency meet

    International Nuclear Information System (INIS)

    Newton, P.J.F.

    1988-01-01

    The Australian Nuclear Science and Technology Organisation (ANSTO) has a direct involvement in nuclear medicine, microbiological and environmental studies which utilise animals in the research work. The opposition to experiments on animals is briefly discussed. The Australia codes of practice for the care and use of animals for experimental purposes are outlined

  18. Expediency of wet-mix shotcreting in mines of Vostoktsvetmet

    Science.gov (United States)

    Shaposhnik, YuN

    2018-03-01

    This paper offers a substantiation of the transition from heavy and difficult-to-install steel frame support to the cheaper and simpler reinforced shotcrete lining (at the same bearing-capacity of the support). The process line for the preparation of the shotcrete mix is designed. The author of the paper presents calculation of the material inputs and labor costs of installation of different support types in Kazakhstan Mines. The economic efficiency of the wet-mix shotcrete spraying technology is illustrated in terms of Orlov and Artemevsk Mines.

  19. the case of orphans and vulnerable children in South Africa

    African Journals Online (AJOL)

    2006-08-02

    Aug 2, 2006 ... Policies are often developed without taking into account social science research findings and recommendations, ... information in the increasingly interconnected ... decision-makers of political expediency that results in.

  20. USSR Report, Consumer Goods and Domestic Trade, No. 35

    National Research Council Canada - National Science Library

    1982-01-01

    PARTIAL CONTENTS: CONSUMER GOODS PRODUCTION AND DISTRIBUTION - Deputy Gosplan Chairman Lakhtin on Consumer Demand, Consumer Co-ps and State Trade Urged To Improve Service, Stepped Up Light Industry Construction Urged...

  1. Estimation to cost-performance of the change acting production capital funds of the rail-freight traffic of the Ukraine

    OpenAIRE

    Kravchenko, O.

    2011-01-01

    In the article is considered problems and tendencies of improvement of railway’s basic funds condition and is proposed the method of economic expediency estimation of substitute of functioning basic funds.

  2. TENDENCIES AND PROSPECTS OF APPLICATION OF HYDROSTATIC-MECHANICAL TRANSMISSION IN CAR- AND TRACTORBUILDING

    OpenAIRE

    V. Samorodov; A. Bondarenko

    2012-01-01

    Research of advantages and lacks of hydrostatic-mechanical transmission, application of hydrostatic-mechanical transmission, expedience of the use of hydrostatic-mechanical transmission on motor transport and agricultural machines have been done.

  3. Testing the influence of external and internal cues on smoking motivation using a community sample.

    Science.gov (United States)

    Litvin, Erika B; Brandon, Thomas H

    2010-02-01

    Exposing smokers to either external cues (e.g., pictures of cigarettes) or internal cues (e.g., negative affect induction) can induce urge to smoke and other behavioral and physiological responses. However, little is known about whether the two types of cues interact when presented in close proximity, as is likely the case in the real word. Additionally, potential moderators of cue reactivity have rarely been examined. Finally, few cue-reactivity studies have used representative samples of smokers. In a randomized 2 x 2 crossed factorial between-subjects design, the current study tested the effects of a negative affect cue intended to produce anxiety (speech preparation task) and an external smoking cue on urge and behavioral reactivity in a community sample of adult smokers (N = 175), and whether trait impulsivity moderated the effects. Both types of cues produced main effects on urges to smoke, despite the speech task failing to increase anxiety significantly. The speech task increased smoking urge related to anticipation of negative affect relief, whereas the external smoking cues increased urges related to anticipation of pleasure; however, the cues did not interact. Impulsivity measures predicted urge and other smoking-related variables, but did not moderate cue-reactivity. Results suggest independent rather than synergistic effects of these contributors to smoking motivation. (PsycINFO Database Record (c) 2010 APA, all rights reserved).

  4. TRANSFORMATION OF WAREHOUSING AND LOGISTICS SYSTEMS (FOR EXAMPLE, INFRASTRUCTURE OF THE ARMED FORCES

    Directory of Open Access Journals (Sweden)

    Timur Khusainovich Kurbanov

    2016-04-01

    Practical implications the results obtained it is expedient to apply the military organization of the state and private companies for further development of the system stationary storage of material and technical means.

  5. to view fulltext PDF

    Indian Academy of Sciences (India)

    345 a-alkoxy acid. Design, synthesis and computational validation of novel ... Two expedient 'one-pot' methods for synthesis of ..... Atom transfer radical polymerization (ATRP). Synthesis and ..... Emission and absorption titrations. Synthesis ...

  6. Tax aggressiveness and corporate social responsibility fluidity in ...

    African Journals Online (AJOL)

    Tax aggressiveness and corporate social responsibility fluidity in Nigerian firms. ... the nexus between shareholding and wider-spectrum stake-holding, where key ... to forge mutually expedient cash flow mechanisms for sustainable corporate ...

  7. Suporte básico de vida: capacitação de agentes penitenciários federais para atuação em situações de urgência/emergência / Basic life support: training of federal penitentiary agents for action in situations of emergency

    Directory of Open Access Journals (Sweden)

    Kênnia Stephanie Morais Oliveira

    2018-04-01

    Full Text Available OBJETIVO: Expor a prática de uma atividade de extensão realizada no intuito capacitar os agentes penitenciários da Penitenciária Federal de Mossoró/RN. MÉTODOS: Para aplicação do Suporte Básico de Vida (SBV em situações de urgência/emergência. A atividade aconteceu no período de novembro de 2012 a setembro de 2013, coordenado por um docente, com a participação de 09 discentes da Faculdade de Enfermagem da Universidade do Estado do Rio Grande do Norte. RESULTADOS: A realização deste trabalho permitiu aos agentes penitenciários aperfeiçoar noções prévias acerca da temática, bem como adquirir novos conhecimentos, tendo em vista a possibilidade de aplicá-los no seu cotidiano no âmbito profissional, como também pessoal. CONCLUSÃO: Nesse sentido, os objetivos do projeto foram contemplados na medida em que foram evidenciados os avanços durante as etapas do ensino-aprendizagem.

  8. Urinary Incontinence

    Science.gov (United States)

    ... Why does urinary incontinence affect more women than men? Women have unique health events, such as pregnancy, ... urge incontinence, urine leakage usually happens after a strong, sudden urge to urinate and before you can ...

  9. Marketing Innovations in the Context of Interaction of Enterprises of the Production and Service Sphere on the Basis of Use of Outsourcing

    Directory of Open Access Journals (Sweden)

    Ivanova Anastasiia I.

    2014-02-01

    Full Text Available The goal of the article lies in development of a methodical approach to identification of expediency of transfer of the production enterprise equipment maintenance to outsourcing, which would consider specific features of the servicing production and degree of its influence upon basic production processes. The existing approaches to identification of expediency of transfer of functions and business processes of an enterprise to outsourcing were systemised by the classification feature of the method type, on the basis of which the approach is built and advantages and shortcomings of each of them are marked out. The article establishes that this grouping could be used as a set of alternatives on justification of introduction of outsourcing into the practice. In accordance with the goal of the study the article builds a methodical approach to identification of expediency of transfer of the production enterprise equipment maintenance, which is based on a comparative analysis of integral ratio of efficiency of own maintenance service and efficiency of maintenance service of outsourcing companies and which takes into account main parameters of functioning and degree of influence of the servicing production upon main business processes. The developed methodical approach could be used as a tool of expansion of sales markets of the service sphere enterprises by means of assessment of needs of customers and establishment of the target-oriented market segment.

  10. Nuclear war survival skills

    International Nuclear Information System (INIS)

    Kearney, C.H.

    1979-09-01

    This book includes chapters on psychological preparations, warning and communications, and evacuation. It describes the building of expedient shelters, their ventilation and cooling, the purification and storage of adequate water, the processing and cooking of whole grains and legumes, fallout meters, protection against fires and carbon monoxide, and expedient furnishings for shelters. Other chapters cover sanitation and preventive medicine, medical advice for nuclear survivors lacking the help of doctors, improvised footwear and clothing, and advice on minimum preparations that can be made at low cost and should be made before a crisis arises. One appendix of the handbook gives detailed, field-tested instructions for building six types of earth-covered expedient fallout shelters, with criteria to guide the choice of which shelter to build. Others contain instructions for making an efficient shelter-ventilating pump and a homemade fallout meter that is accurate and dependable with inexpensive materials found in most households. This report is primarily a compilation and summary of civil defense measures and inventions developed at ORNL over the past 14 years and field-tested in six states, from Florida to Utah. It is the first comprehensive handbook of survival information for use by untrained citizens who want to improve their chances of surviving a possible nuclear attack. Sections may be easily excerpted and reproduced for mass distribution through news media

  11. [Surgery of lower third molars and lesions of the lingual nerve].

    Science.gov (United States)

    Chiapasco, M; Pedrinazzi, M; Motta, J; Crescentini, M; Ramundo, G

    1996-11-01

    The authors describe a technical expedient applied during the removal of totally or partially impacted lower third molars, in order to prevent lingual nerve damage. EXPERIMENTAL ASSAY: Retrospective study. The sample includes 1835 extractions of totally or partially impacted lower third molars, performed on 1030 patients, 493 males and 537 females, aging between 12 and 72 years. All the operations were carried out under local anaesthesia with standardization of the surgical protocol. A mucoperiosteal paramarginal flap was used in case of germectomy, whereas a mucoperiosteal marginal flap with mesial releasing incision was used in case of fully mature teeth. Ostectomy and tooth sectioning were performed using a round and fissure bur respectively, assembled on a straight low-speed handpiece and under irrigation with sterile saline. The authors reported only one case of transient lingual nerve paresthesia (0.05%) which occurred in a 19-years old female presenting a totally impacted third molar mesial-lingual inclination. Symptoms disappeared spontaneously one week postoperatively. Therefore the overall incidence of permanent nerve damage was equal to 0%. The data reported in literature show a lingual nerve lesion incidence ranging between 0% and 22%. With this simple surgical expedient the incidence of permanent lingual damage was 0%. Thus, it is the authors' opinion that this simple expedient should be applied in all cases of impacted third molar removal.

  12. Clerics urge ban on altering germline cells.

    Science.gov (United States)

    Norman, C

    1983-06-24

    A resolution calling for a ban on genetic engineering of human reproductive cells has been signed by leaders of almost every major church group in the United States. Some of the religious leaders, while not certain that a total moratorium should be placed on altering germline cells, signed the statement in order to stimulate public debate on the issue. Legislation has recently been introduced in Congress to set up a committee to monitor genetic engineering and its human applications, but author Jeremy Rifkin, the impetus behind the church leaders' resolution, argues that such tampering threatens the gene pool and should be banned altogether.

  13. EPA urges schools to check for radon

    International Nuclear Information System (INIS)

    Anon.

    1989-01-01

    In April recommended that schools test their facilities for radioactive radon gas after examining preliminary test data from 130 schools scattered across the country which indicated that elevated radon levels may be at least as prevalent in schools as in private residences. EPA is recommending that schools test 100 percent of frequently-used rooms on the basement-level and ground-level floors. The agency also recommends that testing be conducted in the cooler months of the year when doors and windows are likely to be closed. As part of a study to gather more information about measuring radon in schools, EPA tested approximately 3000 classrooms in 16 states. The states are widely distributed across the country. Of the total number of rooms, 54 percent had at least one room with a radon level above four picocuries per liter of air pCi/L. Nineteen percent had radon levels above four pCi/L. Three percent of the classrooms measured had radon level over 20 pCi/L. Each of the 16 states had a school with one measurement over four pCi/L, and one school had levels as high as 136 pCi/L

  14. NASA study backs SSTO, urges shuttle phaseout

    Science.gov (United States)

    Asker, James R.

    1994-03-01

    A brief discusion of a Congressionally ordered NASA study on how to meet future US Government space launch needs is presented. Three options were examined: (1) improvement ofthe Space Shuttle; (2) development of expendable launch vehicles (ELVs); and (3) development of a single-stage-to-orbit (SSTO), manned vehicle that is reusable with advanced technology. After examining the three options, it was determined that the most economical approach to space access through the year 2030 would be to develop the SSTO vehicle and phase out Space Shuttle operations within 15 years and ELVs within 20 years. Other aspects of the study's findings are briefly covered.

  15. Regional Power Authority urged for TMI operations

    International Nuclear Information System (INIS)

    Anon.

    1981-01-01

    If the Three Mile Island (TMI) unit 1 returns to service, state ownership with a Regional Power Authority to oversee its operation and complete the cleanup of unit 2 would benefit ratepayers and avoid lengthy lawsuits, according to an Arthur Young and Company report to the New Jersey Board of Utilities. The report rejects continued ownership by General Public Utilities (GPU), merger, divestiture, and other options. It also outlines several conditions necessary for a Regional Power Authority: adequate rate relief, restart of TMI-1, congressional tax exemption, and approval by the GPU board and stockholders. The report recommends that Jersey Central divest itself of GPU to avoid financial disaster if GPU should declare bankruptcy, but it advises maintaining the flexibility to exercise long-term options

  16. Guidelines Urge Exercise for Cancer Patients, Survivors

    Science.gov (United States)

    The benefits of exercise are well documented in a number of cancers. A panel of experts in cancer, fitness, obesity, and exercise training convened by the American College of Sports Medicine is spreading what they believe to be one of the most important messages for cancer patients and survivors: Avoid inactivity.

  17. U.S. Aid Urged for Education's Entrepreneurs

    Science.gov (United States)

    Robelen, Erik W.

    2008-01-01

    With the presidential candidates both underscoring their support for entrepreneurial initiatives in education, policy experts are advancing ideas for helping such efforts flourish. In their October 15 debate at Hofstra University, both Senators John McCain of Arizona and Barack Obama of Illinois used questions on education to talk about school…

  18. Malaysia urges ASEAN to tackle AIDS crisis.

    Science.gov (United States)

    2000-08-07

    Urgent action is needed to fight the alarming spread of HIV/AIDS that infected 1.3 million people in Southeast Asia last year alone, Malaysia's foreign minister said July 24, 2000. Syed Hamid said the Association of Southeast Asian Nations (ASEAN) should tackle at regional and national level an epidemic that was taking its most drastic toll among the region's youth. "HIV/AIDS not only represents a major public health and social problem but is a serious challenge to development as well," Syed Hamid told the opening ceremony of ASEAN's 33rd annual foreign ministers' meeting. The crisis requires commitment at the "highest political level," he said, warning that HIV/AIDS could become a transnational problem within the 10-member group. Foreign ministers have recommended their leaders discuss the crisis later this year at an informal summit in Singapore and hold a summit on HIV/AIDS in conjunction with the 7th ASEAN Summit in Brunei next year. "I think people recognized the importance and the adverse impacts on our social development," Syed Hamid told reporters later. "I think it is a real issue that we cannot run away from." Among ASEAN members, Thailand, Cambodia, and Myanmar have some of the highest infection rates in Asia of HIV, the virus that causes AIDS. full text

  19. Nurses Urged to Prepare for Sex Education.

    Science.gov (United States)

    2017-01-01

    Editors' note: From its first issue in 1900 through to the present day, AJN has unparalleled archives detailing nurses' work and lives over more than a century. These articles not only chronicle nursing's growth as a profession within the context of the events of the day, but they also reveal prevailing societal attitudes about women, health care, and human rights. Today's nursing school curricula rarely include nursing's history, but it's a history worth knowing. To this end, From the AJN Archives highlights articles selected to fit today's topics and times.This month we reprint a brief "Professional Practice" note from the June 1969 issue about what was described as the first family planning conference for nurse educators. Speakers emphasized the need to make this subject a routine part of nursing school curricula (despite debates over the nurse's role in family planning), "so that nurses can counsel out of wisdom and not from piety or ignorance." Speakers included James Lieberman, MD, who years later coauthored with his daughter a teen sex guide, and Alan Guttmacher, MD, then president of Planned Parenthood, whose Center for Family Planning Program Development within that organization was later renamed the Guttmacher Institute in his honor.Nurses today are deeply involved in sexual and reproductive health care. In this issue, public health specialist Diane Santa Maria and colleagues offer ways to advance sexual and reproductive health care for adolescents by devising more friendly, youth-oriented clinical settings.

  20. The urgency of the course «Information and communication technologies in education»

    OpenAIRE

    Екатерина Михайловна Гулидова

    2010-01-01

    In article the expediency of education of students to discipline «Information and communication technologies in formation» is discussed. The comparative analysis of curriculums is resulted. Making maintenances of education are allocated.

  1. Toward Restoring Some "Punch" in Counselling and Therapy Research and Practice: A Response to Martin.

    Science.gov (United States)

    Van Hesteren, Frank

    1995-01-01

    Reacts to Martin's (1995) essay concerning scientism in psychotherapy. Urges placing a moratorium on the "hermeneutic retreat" advocated by Martin, and urges capitalizing on the unique strengths of both positivistic and interpretive modes of inquiry. (JPS)

  2. U.S. War Powers in the 21st Century: Do Post Cold War Conditions Facilitate Abuse of Executive Prerogative in Foreign Affairs?

    National Research Council Canada - National Science Library

    Anders, R

    2001-01-01

    ...: The Legislative Branch declared, or at least authorized and funded, military intervention. The Cold War led directly to an expedient shift of War Powers towards the Executive Branch, during this period to restore balance...

  3. [Orthorexia--a new diagnosis?].

    Science.gov (United States)

    Janas-Kozik, Małgorzata; Zejda, Jan; Stochel, Martyna; Brozek, Grzegorz; Janas, Adam; Jelonek, Ireneusz

    2012-01-01

    Orthorexia nervosa (Greek: ortho--correct, right; orexis--appetite, desire) is a term introduced in 1997 by the American doctor Steven Bratman and is defined as a pathological fixation with righteous and healthy eating. Clear classification criteria oforthorexia have not been developed yet and there has been an on-going discussion whether it belongs to the group of eating disorders or the obsessive-compulsive disorders. The aim of this paper is to summarise briefly the current state of knowledge regarding orthorexia and to point out the difficulties connected with an attempt to classify it in a given disorders group as well as with the attempt to establish the classification criteria. Despite the fact that the problem of orthorexia has been signalled in the Polish media, it has neither been discussed nor published in the Polish medical literature yet. Orthorexia starts when a diet becomes an escape from life--everyday activities are dominated by planning, buying and preparing "proper" meals. Each departure from this regime causes anxiety and guilty conscience and leads to even further tightening of the dietary habits. According to Bratmann, orthorexia is connected with an illusory feeling of safety (preventing from diseases), the urge to exercise a full control over one's life (elimination of the unpredictable), "a hidden conformism" (eating philosophy helps in a subconscious way to achieve a culturally accepted model of a beautiful body), a search for spirituality and identity, and a desire for self-deprivation. The arguments presented in this paper substantiate the expediency of implementing the epidemiological studies which will show the scale of the problem, its prevalence and conditionings. Data obtained in this way should facilitate the verification of classification criteria and will also help to formulate the diagnostic criteria of orthorexia.

  4. The establishment of MELCOR/SNAP model of Chinshan nuclear power plant for Ultimate Response Guideline

    Energy Technology Data Exchange (ETDEWEB)

    Hsu, Wen-Sheng, E-mail: wshsu@ess.nthu.edu.tw [Nuclear Science and Technology Development Center, Institute of Nuclear Engineering and Science, National Tsing Hua University, Nuclear and New Energy Education and Research Foundation, No. 101, Section 2, Kuang Fu Rd., HsinChu 30013, Taiwan, ROC (China); Chiang, Yu, E-mail: s101013702@m101.nthu.edu.tw [Nuclear Science and Technology Development Center, Institute of Nuclear Engineering and Science, National Tsing Hua University, Nuclear and New Energy Education and Research Foundation, No. 101, Section 2, Kuang Fu Rd., HsinChu 30013, Taiwan, ROC (China); Wang, Jong-Rong, E-mail: jongrongwang@gmail.com [Nuclear Science and Technology Development Center, Institute of Nuclear Engineering and Science, National Tsing Hua University, Nuclear and New Energy Education and Research Foundation, No. 101, Section 2, Kuang Fu Rd., HsinChu 30013, Taiwan, ROC (China); Wang, Ting-Yi, E-mail: minired1119@gmail.com [Nuclear Science and Technology Development Center, Institute of Nuclear Engineering and Science, National Tsing Hua University, Nuclear and New Energy Education and Research Foundation, No. 101, Section 2, Kuang Fu Rd., HsinChu 30013, Taiwan, ROC (China); Wang, Te-Chuan, E-mail: tcwang@iner.gov.tw [Institute of Nuclear Energy Research Atomic Energy Council, R.O.C., 1000, Wenhua Road Jiaan Village, Longtan Township, Taoyuan County 32546, Taiwan (China); Teng, Jyh-Tong, E-mail: jyhtong@cycu.edu.tw [Department of Mechanical Engineering, Chung Yuan Christian University, 200, Chung Pei Rd, Chung Li 32023, Taiwan, ROC (China); Chen, Shao-Wen, E-mail: chensw@mx.nthu.edu.tw [Nuclear Science and Technology Development Center, Institute of Nuclear Engineering and Science, National Tsing Hua University, Nuclear and New Energy Education and Research Foundation, No. 101, Section 2, Kuang Fu Rd., HsinChu 30013, Taiwan, ROC (China); and others

    2017-01-15

    Highlights: • The establishment of a MELCOR/SNAP model of Chinshan (BWR/4). • MELCOR/SNAP model was used to estimate the effectiveness of URG for Chinshan. • The MELCOR results were compared to MAAP, TRACE and PCTRAN. • URG is a new method to prevent a Fukushima-like accident. • The low raw water (150 GPM) can make the cladding temperature below 1088.7 K. - Abstract: After Fukushima Daiichi disaster, the safety analysis of severe accidents became one of the safety concerns in Taiwan. The Emergency Operating Procedure (EOP) cannot cope with a multiple system failure situation under a severe accident since it is a “Symptom-basis” procedure. To deal with that, Taiwan Power Company built up a new strategy for Fukushima-like accident called Ultimate Response Guideline (URG). It is a simple strategy with three main conditions: loss of regular motor driven injection system, loss of all AC power and tsunami/earthquake warning. If two of three happen, the operating procedure will change from EOP to URG and start the main works by following the strategy. There are three main works in URG: controlled-depressurization, line up low pressure injection water and prepare containment venting. In this study, MELCOR2.1 was used to calculate the cases of URG and checked the goal of the strategy that prevents the accident or not. There were three steps in this research. First, a model of Chinshan nuclear power plant (NPP) was built. Second, one was the case with URG and the other was not by using the above MELCOR model. The results were compared to MAAP5.0, TRACE and PCTRAN. Finally, some sensitivity studies of depressurization and water injection rate were done.

  5. Passive exposure to electronic cigarette (e-cigarette) use increases desire for combustible and e-cigarettes in young adult smokers.

    Science.gov (United States)

    King, Andrea C; Smith, Lia J; McNamara, Patrick J; Matthews, Alicia K; Fridberg, Daniel J

    2015-09-01

    Passive exposure to combustible cigarette use has been shown to act as a cue to increase smoking urge. Given the resemblance of e-cigarettes and other electronic nicotine delivery systems (ENDS) to combustible cigarettes, we examined whether these devices could also act as a cue to increase smoking desire and urges in those passively exposed. Young adult daily smokers (age 18-35 years; N=60) completed subjective ratings before and after exposure to a study confederate drinking bottled water (control cue) and then smoking either a combustible or e-cigarette (active cue). Smoking desire and urge ratings were measured with visual analogue scale items for desire for a regular and an e-cigarette and the Brief Questionnaire of Smoking Urges. Passive exposure to both the e-cigarette and combustible cigarette cue significantly increased observers' ratings of desire and urge to smoke a regular cigarette (all ps<0.05). Exposure to the e-cigarette cue but not the regular cigarette cue also increased desire to smoke an e-cigarette (p<0.01). The results provide the first evidence in a controlled setting that electronic cigarette exposure may evoke smoking urges in young adult daily smokers. With replication, these findings may have relevance for ENDS regulation and policy. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  6. Enhanced Inhibitory Effect of Ultra-Fine Granules of Red Ginseng on LPS-induced Cytokine Expression in the Monocyte-Derived Macrophage THP-1 Cells

    Directory of Open Access Journals (Sweden)

    Hong-Yeoul Kim

    2008-08-01

    Full Text Available Red ginseng is one of the most popular traditional medicines in Korea because its soluble hot-water extract is known to be very effective on enhancing immunity as well as inhibiting inflammation. Recently, we developed a new technique, called the HACgearshift system, which can pulverize red ginseng into the ultra-fine granules ranging from 0.2 to 7.0 μm in size. In this study, the soluble hot-water extract of those ultra-fine granules of red ginseng (URG was investigated and compared to that of the normal-sized granules of red ginseng (RG. The high pressure liquid chromatographic analyses of the soluble hot-water extracts of both URG and RG revealed that URG had about 2-fold higher amounts of the ginsenosides, the biologically active components in red ginseng, than RG did. Using quantitative RT-PCR, cytokine profiling against the Escherichia coli lipopolysaccharide (LPS in the monocyte-derived macrophage THP-1 cells demonstrated that the URG-treated cells showed a significant reduction in cytokine expression than the RG-treated ones. Transcription expression of the LPS-induced cytokines such as TNF-α, IL-1β, IL-6, IL-8, IL-10, and TGF-β was significantly inhibited by URG compared to RG. These results suggest that some biologically active and soluble components in red ginseng can be more effectively extracted from URG than RG by standard hot-water extraction.

  7. Bothersome Tics in Patients with Chronic Tic Disorders: Characteristics and Individualized Treatment Response to Behavior Therapy

    Science.gov (United States)

    McGuire, Joseph F.; Piacentini, John; Scahill, Lawrence; Woods, Douglas W.; Villarreal, Robert; Wilhelm, Sabine; Walkup, John T.; Peterson, Alan L.

    2015-01-01

    This report examined the most frequently reported bothersome tics among individuals with chronic tic disorders and evaluated the improvement and remission of tics and their associated characteristics. Youths and adults (N = 240) were randomly assigned to receive the comprehensive behavioral intervention for tics (CBIT) or psychoeducation and supportive therapy (PST). At baseline, motor tics and tics with an urge were rated as more bothersome relative to vocal tics and tics without premonitory urges. The five most common bothersome tics included eye blinking, head jerks, sniffing, throat clearing, and other complex motor tics. While CBIT outperformed PST across tic type and urge presence, tics preceded by premonitory urges at baseline had higher severity at posttreatment across treatment condition. Six individual tic types had lower severity at posttreatment following CBIT relative to PST. Baseline urge presence was associated with tic remission for CBIT but not PST. Specific bothersome tics were more likely to remit with CBIT relative to PST. Findings suggest that individual tics respond and remit differently to CBIT relative to PST, with implications highlighting the negative reinforcement hypothesis in tic symptom maintenance. PMID:25988365

  8. Tic-related cognition, sensory phenomena, and anxiety in children and adolescents with Tourette syndrome.

    Science.gov (United States)

    Steinberg, Tamar; Harush, Adva; Barnea, Meirav; Dar, Rueven; Piacentini, John; Woods, Doug; Shmuel-Baruch, Sharona; Apter, Alan

    2013-07-01

    Tourette syndrome is a protoypical example of developmental psychopathology, with the varying expressions of the disorder and its consequences appearing over time. Sensory urges typically appear after age 10 and are often followed by anxiety and depression. To study the associations among tic-related cognitions, premonitory urges, and tic severity in children with Tourette syndrome at different stages of the illness. Fifty-seven consecutive patients referred to a tic disorders clinic. A battery of instruments was completed: Yale Global Tic Severity Scale, Premonitory Urge for Tics Scale, Screen for Child Anxiety Related Emotional Disorders, and Child Depression Inventory. To examine cognitions, a new measure was developed: the Beliefs About Tics Scale. Strong correlations were found between tic-related beliefs and both premonitory urges and tic-related impairments (as measured by the Yale Global Scale). Tic-related beliefs were also strongly correlated with depression in children older than 13 years but not in younger children. The significant correlations between tic-related cognitions, premonitory urges, and tic-related impairments in children emphasize the important role of psychological and sensory factors in the understanding of Tourette syndrome and in its treatment. Copyright © 2013 Elsevier Inc. All rights reserved.

  9. Bothersome tics in patients with chronic tic disorders: Characteristics and individualized treatment response to behavior therapy.

    Science.gov (United States)

    McGuire, Joseph F; Piacentini, John; Scahill, Lawrence; Woods, Douglas W; Villarreal, Robert; Wilhelm, Sabine; Walkup, John T; Peterson, Alan L

    2015-07-01

    This report examined the most frequently reported bothersome tics among individuals with chronic tic disorders and evaluated the improvement and remission of tics and their associated characteristics. Youths and adults (N = 240) were randomly assigned to receive the comprehensive behavioral intervention for tics (CBIT) or psychoeducation and supportive therapy (PST). At baseline, motor tics and tics with an urge were rated as more bothersome relative to vocal tics and tics without premonitory urges. The five most common bothersome tics included eye blinking, head jerks, sniffing, throat clearing, and other complex motor tics. While CBIT outperformed PST across tic type and urge presence, tics preceded by premonitory urges at baseline had higher severity at posttreatment across treatment condition. Six individual tic types had lower severity at posttreatment following CBIT relative to PST. Baseline urge presence was associated with tic remission for CBIT but not PST. Specific bothersome tics were more likely to remit with CBIT relative to PST. Findings suggest that individual tics respond and remit differently to CBIT relative to PST, with implications highlighting the negative reinforcement hypothesis in tic symptom maintenance. CLINICALTRIALS. NCT00218777; NCT00231985. Published by Elsevier Ltd.

  10. Heated Aluminum Tanks Resist Corrosion

    Science.gov (United States)

    Johnson, L. E.

    1983-01-01

    Simple expedient of heating foam-insulated aluminum alloy tanks prevents corrosion by salt-laden moisture. Relatively-small temperature difference between such tank and surrounding air will ensure life of tank is extended by many years.

  11. Pyrazole carboxamides and carboxylic acids as protein kinase inhibitors in aberrant eukaryotic signal transduction

    DEFF Research Database (Denmark)

    Persson, Tobias; Yde, Christina W.; Rasmussen, Jakob Ewald

    2007-01-01

    Densely functionalised pyrazole carboxamides and carboxylic acids were synthesised in an expedient manner through saponification and transamidation, respectively, of ester-functionalised pyrazoles. This synthetic protocol allowed for three diversifying steps in which appendages on the pyrazole...

  12. Speak Up: Help Prevent Errors in Your Care: Laboratory Services

    Science.gov (United States)

    SpeakUP TM Help Prevent Errors in Your Care Laboratory Services To prevent health care errors, patients are urged to... SpeakUP TM ... are more likely to get better faster. To help prevent health care mistakes, patients are urged to “ ...

  13. Serviço de Atendimento Móvel às Urgências Cuiabá: desafios e possibilidades para profissionais de enfermagem Servicio de Atención Móvil a las Urgencias Cuiabá: desafíos y posibilidades para profesionales de enfermería Cuiabá Mobile Emergency Service: challenges and opportunities for nursing professionals

    Directory of Open Access Journals (Sweden)

    Damaris Leonel Brito Figueiredo

    2009-10-01

    Full Text Available O Serviço de Atendimento Móvel às Urgências um dos focos da Política Nacional de Atenção às Urgências que tem sido implantado no território nacional, iniciou em 2004, no município de Cuiabá, Estado de Mato Grosso sendo habilitado apenas em 2007. O estudo relata a experiência de uma das autoras como enfermeira do Atendimento Pré-Hospitalar (APH, participante do processo de implantação do serviço. Até 2004, em Mato Grosso, o atendimento às urgências era realizado exclusivamente pelo Corpo de Bombeiros (CB. A reformulação do APH possibilitou a inserção de profissionais de enfermagem em uma área não conquistada por essa profissão neste município. Tal reestruturação implicou desvinculação do CB, mudança para sede própria e desenvolvimento das atividades relacionadas ao serviço apenas por civis. Conclui-se que a nova possibilidade de atuação para profissionais de enfermagem impulsionou a busca de especializações e desenvolvimento de estudos que subsidiem a atuação prática nesse ambiente.El Servicio de Atención Móvil a las Urgencias, uno de los elementos centrales de la Política Nacional de Atención a las Urgencias que se ha implantado en el territorio nacional, se inició en el 2004, en el municipio de Cuiabá, Estado de Mato Grosso siendo habilitado sólo en el 2007. El estudio relata la experiencia de una de las autoras como enfermera de la Atención Pre Hospitalaria (APH, que participó del proceso de implantación del servicio. Hasta 2004, en Mato Grosso, la atención a las urgencias era realizada exclusivamente por el Cuerpo de Bomberos (CB. La reformulación del APH posibilitó la inserción de profesionales de enfermería en un área no ganada por este gremio en el Municipio de Cuiabá. Tal reestructuración implicó la desvinculación del CB, el traslado a una sede propia y desarrollo de las actividades relacionadas al servicio apenas por civiles. Se concluye que la nueva posibilidad de actuaci

  14. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ′)-diones has been expediently accomplished by a reaction of isatin(s) / cyclic ketone and anthranilamide in ethanol at ambient temprature. Excellent yields of the products in short time duration, operational simplicity, and simple work-up ...

  15. Electronic word of mouth influence on consumer purchase intention ...

    African Journals Online (AJOL)

    This type of e-marketing affects consumer on its purchase intention of product or service. ... influence and how these factors influence the buying decisions of consumers. ... This paper is expedient for marketers in creating effective promotional ...

  16. Broadband antenna for ground penetrating radar application in soil

    Science.gov (United States)

    Shebalkova, LV; Markov, MA; Romodin, VB

    2018-03-01

    The scope of the article embraces the features of design of antennas and arrays for GPR, their type and parameters and the expediency of the application of the antenna arrays in various purpose location systems of GPR.

  17. Empiric reliability of diagnostic and prognostic estimations of physical standards of children, going in for sports.

    Directory of Open Access Journals (Sweden)

    Zaporozhanov V.A.

    2012-12-01

    Full Text Available In the conditions of sporting-pedagogical practices objective estimation of potential possibilities gettings busy already on the initial stages of long-term preparation examined as one of issues of the day. The proper quantitative information allows to individualize preparation of gettings in obedience to requirements to the guided processes busy. Research purpose - logically and metrical to rotin expedience of metrical method of calculations of reliability of results of the control measurings, in-use for diagnostics of psychophysical fitness and prognosis of growth of trade gettings busy in the select type of sport. Material and methods. Analysed the results of the control measurings on four indexes of psychophysical preparedness and estimation of experts of fitness 24th gettings busy composition of children of gymnastic school. The results of initial and final inspection of gymnasts on the same control tests processed the method of mathematical statistics. Expected the metrical estimations of reliability of measurings is stability, co-ordination and informing of control information for current diagnostics and prognosis of sporting possibilities inspected. Results. Expedience of the use in these aims of metrical operations of calculation of complex estimation of the psychophysical state of gettings busy is metrology grounded. Conclusions. Research results confirm expedience of calculation of complex estimation of psychophysical features gettings busy for diagnostics of fitness in the select type of sport and trade prognosis on the subsequent stages of preparation.

  18. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Keywords. -aryl--mercaptoketones; anhydrous potassium carbonate; amberlyst-15; chalcones; thia-Michael addition. Abstract. Two expedient one-pot methods have been developed for synthesis of -aryl--mercaptoketones using acetophenones, benzaldehydes and thiols as starting materials. The methods involve ...

  19. Use of data libraries in dosimetry control systems

    International Nuclear Information System (INIS)

    Babenko, V.V.; Babenko, M.I.; Kazimirov, A.S.

    2002-01-01

    Analysis, prediction and planning of dose loads, adequacy in dose management of personnel, evaluation of expediency and sufficiency of existing radiation protection system can be realized with the help of database system of dosimetry control in 'Ukrytie'-shelter

  20. Experience gained with certification of instruments for the system for nuclear material physical protection, accounting, and control

    International Nuclear Information System (INIS)

    Gus'kov, O.M.; Egorov, V.V.; Morozov, O.S.; Novikov, V.M.

    1999-01-01

    Results of the tests have confirmed the expedience of certification of the equipment, especially imported items. For the use of imported equipment at Russian facilities, it is justified to accommodate the accompanying documents thereto for the Russian standards. Equipment items shipped to Russia should be prepared for the certification tests and/or operation. When taking decision on the certification of imported equipment, it is expedient to preliminarily estimate the instrument's parameters and its operation in Russia. To solve the question whether the imported equipment is usable for Russia and what engineering support and maintenance is needed for its operation, it would be justified to create the Center for engineering support of instruments to be used for nuclear material protection, control and accounting on the basis of one of institutes dealing with the development of instruments for these application [ru

  1. Compulsive carnival song whistling following cardiac arrest: a case study

    NARCIS (Netherlands)

    Polak, A. Rosaura; van der Paardt, Jasper W.; Figee, Martijn; Vulink, Nienke; de Koning, Pelle; Olff, Miranda; Denys, Damiaan

    2012-01-01

    Compulsivity is the repetitive, irresistible urge to perform a behavior, the experience of loss of voluntary control over this intense urge and the tendency to perform repetitive acts in a habitual or stereotyped manner. Compulsivity is part of obsessive-compulsive disorder (OCD), but may

  2. Adult female urinary incontinence and childhood bedwetting

    DEFF Research Database (Denmark)

    Foldspang, Anders; Mommsen, S.

    1994-01-01

    A cross-sectional random population sample of women 30 to 59 years old was sent a questionnaire on urinary incontinence and, among other things, childhood bedwetting. Among 2,613 responders 17.0% reported prevalent urinary incontinence (14.7% stress provoked, 8.3% associated with urge, 6.8% stress...... and urge overlap, 2.2% occurring especially during sleep and 3.9% occurring especially when anxious), and 6.5% reported childhood bedwetting after age 5 years and 3.3% after age 10 years. Childhood bedwetting was associated with prevalent urge urinary incontinence (p ... during sleep (p anxiety (p

  3. Dosimeter charging apparatus

    International Nuclear Information System (INIS)

    Reuter, F.A.; Moorman, Ch.J.

    1985-01-01

    An apparatus for charging a dosimeter which has a capacitor connected between first and second electrodes and a movable electrode in a chamber electrically connected to the first electrode. The movable electrode deflects varying amounts depending upon the charge present on said capacitor. The charger apparatus includes first and second charger electrodes couplable to the first and second dosimeter electrodes. To charge the dosimeter, it is urged downwardly into a charging socket on the charger apparatus. The second dosimeter electrode, which is the dosimeter housing, is electrically coupled to the second charger electrode through a conductive ring which is urged upwardly by a spring. As the dosimeter is urged into the socket, the ring moves downwardly, in contact with the second charger electrode. As the dosimeter is further urged downwardly, the first dosimeter electrode and first charger electrode contact one another, and an insulator post carrying the first and second charger electrodes is urged downwardly. Downward movement of the post effects the application of a charging potential between the first and second charger electrodes. After the charging potential has been applied, the dosimeter is moved further into the charging socket against the force of a relatively heavy biasing spring until the dosimeter reaches a mechanical stop in the charging socket

  4. Detection of a prosthetic aortic valvular abscess with indium-111-labeled leukocytes

    Energy Technology Data Exchange (ETDEWEB)

    Oates, E.; Sarno, R.C.

    1988-10-01

    An unsuspected annular abscess at the base of a prosthetic aortic valve in a patient with endocarditis was identified by indium-111-labeled leukocyte scintigraphy alone. This highly sensitive and specific technique expediently demonstrated the surgically proven inflammatory focus.

  5. MOLECULAR DIAGNOSTICS - ANOTHER PIECE IN THE ENVIRONMENTAL PUZZLE

    Science.gov (United States)

    Molecular biology offers sensitive and expedient tools for the detection of exposure to environmental stressors. Molecular approaches provide the means for detection of the "first cellular event(s)" in response to environmental changes-specifically, immediate changes in gene expr...

  6. Electrica.l Insta.lla.tions in Multi-storey Buildings

    African Journals Online (AJOL)

    different diversity factors of the individual sections. However .... auxiliary drives for the heating system and ventila- tion, as well as ... For multi-storey buildings preference is generally given to ... Group p. f correction is expedient if large banks of.

  7. Detection of a prosthetic aortic valvular abscess with indium-111-labeled leukocytes

    International Nuclear Information System (INIS)

    Oates, E.; Sarno, R.C.

    1988-01-01

    An unsuspected annular abscess at the base of a prosthetic aortic valve in a patient with endocarditis was identified by indium-111-labeled leukocyte scintigraphy alone. This highly sensitive and specific technique expediently demonstrated the surgically proven inflammatory focus

  8. Teaching Fairness in Journalism: A Challenging Task

    Science.gov (United States)

    Weber, Joseph

    2016-01-01

    Objectivity has long been contentious in American journalism. Many practitioners call it essential to a news organization's credibility. Critics, however, hold objectivity is impossible and urge reporters simply to reveal their biases. For educators, teaching objectivity is challenging. Some, seeking a middle ground, instead urge fairness and…

  9. Estimation of small surface displacements in the Upper Rhine Graben area from a combined analysis of PS-InSAR, levelling and GNSS data

    NARCIS (Netherlands)

    Fuhrmann, T.; Caro Cuenca, M.; Knöpfler, A.; Leijen, F.J. van; Mayer, M.; Westerhaus, M.; Hanssen, R.F.; Heck, B.

    2015-01-01

    The intra-plate deformation of the Upper Rhine Graben (URG) located in Central Europe is investigated using geodetic measurement techniques. We present a new approach to calculate a combined velocity field from InSAR, levelling and GNSS measurements. As the expected tectonic movements in the URG

  10. Compulsivity in obsessive-compulsive disorder and addictions

    NARCIS (Netherlands)

    Figee, Martijn; Pattij, Tommy; Willuhn, Ingo; Luigjes, Judy; van den Brink, Wim; Goudriaan, Anneke; Potenza, Marc N; Robbins, Trevor W; Denys, D.

    2016-01-01

    Compulsive behaviors are driven by repetitive urges and typically involve the experience of limited voluntary control over these urges, a diminished ability to delay or inhibit these behaviors, and a tendency to perform repetitive acts in a habitual or stereotyped manner. Compulsivity is not only a

  11. The Brussels Declaration

    DEFF Research Database (Denmark)

    Holgate, S; Bisgaard, H; Bjermer, L

    2008-01-01

    on Asthma, sponsored by The Asthma, Allergy and Inflammation Research Charity, was developed to call attention to the shortfalls in asthma management and to urge European policy makers to recognise that asthma is a public health problem that should be a political priority. The Declaration urges recognition...

  12. Aripiprazole Injection

    Science.gov (United States)

    ... for them, such as increased sexual urges or behaviors, excessive shopping, and binge eating. Call your doctor if you have intense urges to shop, eat, have sex, or gamble, or if you are unable to control your behavior. Tell your family members about this risk so ...

  13. Common Virtual Path and Its Expedience for VBR Video Traffic

    Directory of Open Access Journals (Sweden)

    E. Chromy

    2008-04-01

    Full Text Available The paper deals with utilization of common Virtual Path (VP for variable bit rate (VBR video service. Video service is one of the main services for broadband networks. Research is oriented to statistical properties of common and separate VPs. Separate VP means that for each VBR traffic source one VP will be allocated. Common VP means that for multiple VBR sources one common VP is allocated. VBR video traffic source is modeled by discrete Markov chain.

  14. Obsessive-compulsive symptoms and negative affect during tobacco withdrawal in a non-clinical sample of African American smokers.

    Science.gov (United States)

    Bello, Mariel S; Pang, Raina D; Chasson, Gregory S; Ray, Lara A; Leventhal, Adam M

    2017-05-01

    The association between obsessive-compulsive (OC) symptomatology and smoking is poorly understood, particularly in African Americans-a group subject to smoking- and OC-related health disparities. In a non-clinical sample of 253 African American smokers, we tested the negative reinforcement model of OC-smoking comorbidity, purporting that smokers with higher OC symptoms experience greater negative affect (NA) and urge to smoke for NA suppression upon acute tobacco abstinence. Following a baseline visit involving OC assessment, participants completed two counterbalanced experimental visits (non-abstinent vs. 16-h tobacco abstinence) involving affect, smoking urge, and nicotine withdrawal assessment. OC symptom severity predicted larger abstinence-provoked increases in overall NA, anger, anxiety, depression, fatigue, urge to smoke to suppress NA, and composite nicotine withdrawal symptom index. African American smokers with elevated OC symptoms appear to be vulnerable to negative reinforcement-mediated smoking motivation and may benefit from cessation treatments that diminish NA or the urge to quell NA via smoking. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. Incidence and remission of lower urinary tract symptoms during 12 years after the first delivery: A cohort study

    DEFF Research Database (Denmark)

    Viktrup, L.; Lose, G.

    2008-01-01

    Purpose: We estimated the incidence and remission of lower urinary tract symptoms during the 12 years following the first pregnancy and delivery. Materials and Methods: In a cohort study 242 primiparae were questioned about lower urinary tract symptoms 3 months, 5 years and 12 years after the first...... of stress urinary incontinence, urge urinary incontinence, urgency, diurnal frequency and nocturia during the same period occurred in 1 of 11 cases (9.1%), 2 of 5 (40%), 2 of 5 (40%), 4 of 7 (57.1%) and I of 1 (100%), respectively. From 5 to 12 years after the first delivery the incidence of stress urinary...... urge urinary incontinence and 15 (24.2%) had mixed urinary incontinence 12 years later. Of 13 women with pure urge urinary incontinence during the first pregnancy and puerperium 3 (23.1%) had pure urge urinary incontinence, 2 (15.4%) had pure stress urinary incontinence and 3 (23.1%) had mixed urinary...

  16. Running with technology: Where are we heading?

    DEFF Research Database (Denmark)

    Jensen, Mads Møller; Mueller, Florian 'Floyd'

    2014-01-01

    technique- related information in run-training interfaces. From that finding, this paper presents three questions to be addressed by designers of future run-training interfaces. We believe that addressing these questions will support creation of expedient interfaces that improve runners’ technique...

  17. Pavement, bridge, and safety cost evaluation tool for overweight truck corridors serving coastal port regions and border ports of entry

    Science.gov (United States)

    2017-08-01

    To address the need for a rational but fast method to determine costs and a proposed permit fee, the research team developed the Stage 1 Expedient Analysis Method. The method was used to evaluate potential oversize/overweight (OS/OW) freight corridor...

  18. Features of the Ussr State Information Policy Around the Chernobyl NPP in the First Weeks after the Disaster

    Directory of Open Access Journals (Sweden)

    O. Makhno

    2016-02-01

    Full Text Available The article analyzes the Soviet information policy regarding the Chernobyl accident in the first weeks after the disaster. Grounded conclusion of concealment and manipulation of information by public authorities and manipulating it, the principle of political expediency.

  19. Tobacco withdrawal symptoms mediate motivation to reinstate smoking during abstinence.

    Science.gov (United States)

    Aguirre, Claudia G; Madrid, Jillian; Leventhal, Adam M

    2015-08-01

    Withdrawal-based theories of addiction hypothesize that motivation to reinstate drug use following acute abstinence is mediated by withdrawal symptoms. Experimental tests of this hypothesis in the tobacco literature are scant and may be subject to methodological limitations. This study utilized a robust within-subject laboratory experimental design to investigate the extent to which composite tobacco withdrawal symptomatology level and 3 unique withdrawal components (i.e., low positive affect, negative affect, and urge to smoke) mediated the effect of smoking abstinence on motivation to reinstate smoking. Smokers (≥10 cigarettes per day; N = 286) attended 2 counterbalanced sessions at which abstinence duration was differentially manipulated (1 hr vs. 17 hr). At both sessions, participants reported current withdrawal symptoms and subsequently completed a task in which they were monetarily rewarded proportional to the length of time they delayed initiating smoking, with shorter latency reflecting stronger motivation to reinstate smoking. Abstinence reduced latency to smoking initiation and positive affect and increased composite withdrawal symptom level, urge, and negative affect. Abstinence-induced reductions in latency to initiating smoking were mediated by each withdrawal component, with stronger effects operating through urge. Combined analyses suggested that urge, negative affect, and low positive affect operate through empirically unique mediational pathways. Secondary analyses suggested similar effects on smoking quantity, few differences among specific urge and affect subtypes, and that dependence amplifies some abstinence effects. This study provides the first experimental evidence that within-person variation in abstinence impacts motivation to reinstate drug use through withdrawal. Urge, negative affect, and low positive affect may reflect unique withdrawal-mediated mechanisms underlying tobacco addiction. (c) 2015 APA, all rights reserved).

  20. Learning Science, Learning about Science, Doing Science: Different Goals Demand Different Learning Methods

    Science.gov (United States)

    Hodson, Derek

    2014-01-01

    This opinion piece paper urges teachers and teacher educators to draw careful distinctions among four basic learning goals: learning science, learning about science, doing science and learning to address socio-scientific issues. In elaboration, the author urges that careful attention is paid to the selection of teaching/learning methods that…

  1. INTEGRATION OF ECONOMIC AND COMPUTER SKILLS AT IMPLEMENTATION OF STUDENTS PROJECT «BUSINESS PLAN PRODUCING IN MICROSOFT WORD»

    Directory of Open Access Journals (Sweden)

    Y.B. Samchinska

    2012-07-01

    Full Text Available In the article expedience at implementation of economic specialities by complex students project on Informatics and Computer Sciences is grounded on creation of business plan by modern information technologies, and also methodical recommendations are presented on implementation of this project.

  2. Cartographic Communication and Information Policy.

    Science.gov (United States)

    van de Waal, E. Hans

    Trends in information policy are discussed as they impact on cartographic information, stressing particularly the relationships between cartographic communication, documentation, and policy making. Distinction is made between cartographic communication as a subject for information policy and cartographic communication as an expedient in public…

  3. Rapid and convenient semi-automated microwave-assisted solid-phase synthesis of arylopeptoids

    DEFF Research Database (Denmark)

    Rasmussen, Jakob Ewald; Boccia, Marcello Massimo; Nielsen, John

    2014-01-01

    A facile and expedient route to the synthesis of arylopeptoid oligomers (N-alkylated aminomethyl benz-amides) using semi-automated microwave-assisted solid-phase synthesis is presented. The synthesis was optimized for the incorporation of side chains derived from sterically hindered or unreactive...

  4. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Synthesis of 2-(oxadiazolo, pyrimido, imidazolo, and benzimidazolo) substituted analogues of 1,4-benzodiazepin-5-carboxamides linked through a phenoxyl bridge ... Exceedingly facile single-step expedient protocols based on the versatility and reactivity of corresponding intermediates amidine and imidate (8 and 9), ...

  5. Fuel Application Efficiency in Ideal Cycle of Gas Turbine Plant with Isobaric Heat Supply

    Directory of Open Access Journals (Sweden)

    A. P. Nesenchuk

    2013-01-01

    Full Text Available The paper reveals expediency to use in prospect fuels with maximum value  Qнр∑Vi and minimum theoretical burning temperature in order to obtain maximum efficiency of the ideal cycle in GTP with isobaric heat supply.

  6. Understanding the Drivers Behind Software Acquisition Program Performance: Enabling Mission Success through Improved Software Decision-Making

    Science.gov (United States)

    2013-04-10

    2013 Carnegie Mellon University Systems Archetypes Systems Archetypes -2 Shifting the Burden (" Addiction ") • An expedient solution temporarily...scrambles signals to exclude those who don’t pay • Example: Tollways Formalize ownership rights • Example: Buffalo, whales neared extinction because they

  7. Application of ICT-based Learning Resources for University Inorganic Chemistry Course Training

    Directory of Open Access Journals (Sweden)

    Tatyana M. Derkach

    2013-01-01

    Full Text Available The article studies expediency and efficiency of various ICT-based learning resources use in university inorganic chemistry course training, detects difference of attitudes toward electronic resources between students and faculty members, which create the background for their efficiency loss

  8. Tax incentives for the economic activity of small businesses

    Directory of Open Access Journals (Sweden)

    Imanshapieva Mazika Musabekovna

    2012-08-01

    Full Text Available In article it is shown that the developed structure of the Russian small business doesn't answer problems of modernization of economy, taking into account features of subjects of small business necessity of strengthening of a role of a tax policy for regulation of their activity is given reason. The expediency of introduction in the Tax code of the Russian Federation of concepts «subjects of small business», «the small innovative enterprise» is proved. Necessity of specification of conditions and signs of reference of the organizations to subjects of small-scale business is revealed at application of the simplified system of the taxation. The expediency of change of existing approaches to formation of tax base at application of the general system of the taxation is established and recommendations about tax stimulation of economic activity of subjects of small business are offered.

  9. The Outsourcing as a Means to Organize the Marketing Analysi

    Directory of Open Access Journals (Sweden)

    Ivanenko Valentyna O.

    2017-08-01

    Full Text Available The article is aimed at substantiating expediency of the use of outsourcing as a means to organize the marketing analysis. The article is concerned with the theoretical-methodical foundations of using the outsourcing marketing analysis, in particular: approaches to interpretation of outsourcing have been considered and the key aspects that characterize it have been allocated; benefits of using the outsourcing marketing analysis have been proven; the main tasks of marketing analysis, which would be expedient to use for outsourcing, have been allocated; the basic criteria for choosing the external professionals when using the outsourcing of marketing analysis have been defined; stages of marketing analysis in terms of using the outsourcing have been proposed, as well as indicators for qualitative and quantitative evaluation of the efficiency of outsourcing of marketing analysis; a scale for the proposed coefficient of efficiency of the outsourcing of marketing analysis has been substantiated.

  10. RESEARCH OF THE MAIN FORMS OF REFINANCING OF RECEIVABLES OF THE ENTERPRISES AT THE PRESENT STAGE

    Directory of Open Access Journals (Sweden)

    I. V. Sukhomlin

    2014-04-01

    Full Text Available In article modern forms of refinancing of receivables for management of enterprise mutual settlements are investigated, namely: factoring, the accounting of the bills issued by buyers of production, forfeyting, the commercial credit. Advantages of the enterprises are defined at application of factoring operations. Characteristic signs of a forfeyting are defined, its advantages are analysed. Expediency of introduction of the commercial credit on the basis of circulation of bills is analysed.Purpose. To investigate modern forms of refinancing of receivables and to consider possibility of their use at the enterprise. To analyse influence of factoring operations on activity of the enterprises. To define expediency of introduction of the commercial credit on the basis of circulation of bills.Method or methodology of carrying out work. Work is performed by results of research of modern domestic and foreign views on advantages of use of the main forms of refinancing of receivables of the enterprises as means of increase of solvency at the present stage.Results. The main forms of refinancing of receivables, including such as are investigated: factoring, forfeyting, commercial credit. Advantages of the enterprises are defined at application of factoring operations. Characteristic signs of a forfeyting are considered, its advantages are analysed. Expediency of introduction of the commercial credit on the basis of circulation of bills is defined.Scope of results. The recommendations offered in article can be used by the enterprises of Ukraine of all forms of ownership for solvency increase at the present stage.Purchase on Elibrary.ru > Buy now

  11. Academics urge Europe to suspend funds for Israel

    CERN Multimedia

    2002-01-01

    A total of 125 academics have demanded that Israel should be prevented from receiving funds from European research organizations until it opens peace negotiations with the Palestinians (4 paragraphs).

  12. Orbach urges renewed commitment to nuclear physics work

    CERN Multimedia

    Jones, D

    2002-01-01

    According to US Office of Science director Raymond Orbach, the Energy Department plans to issue a background paper in the coming months that will make the case for supporting the department's accelerator program for nuclear physics research (1 page).

  13. Conference urges States to ratify nuclear test ban

    International Nuclear Information System (INIS)

    2007-12-01

    Article XIV of the CTBT deals with the treaty's entry into force. The article foresees a mechanism of regular conferences to promote the treaty's entry into force, if this has not taken place three years after its opening for signature. The first such Conference took place in Vienna in 1999. Subsequent Conferences were held in new y ork in 2001 and in 2005, and in Vienna in 2003 and in 2007. The Secretary-general of the United nations convenes the conference at the request of States that have ratified the treaty. Representatives of ratifying States are invited to participate in the deliberations. Signatory States, non-signatory States, international organizations and non-governmental organizations are invited to attend as observers.

  14. Managers urged to care more for their staff.

    Science.gov (United States)

    1990-09-19

    National Health Service staffing problems will never be solved unless management philosophy radically changes co enable nurses to cherish their work, RCN Policy and Research Director Derek Dean warned.

  15. Urging Affordable Access to High-Value Cancer Drugs

    Science.gov (United States)

    This infographic highlights some of the main messages from the President’s Cancer Panel report Promoting Value, Affordability, and Innovation in Cancer Drug Treatment. The graphic includes the panel’s recommendations to maximize the value and affordability of cancer drug treatment.

  16. ATD-1 ATM Technology Demonstration-1 and Integrated Scheduling

    Science.gov (United States)

    Quon, Leighton

    2014-01-01

    Enabling efficient arrivals for the NextGen Air Traffic Management System and developing a set of integrated decision support tools to reduce the high cognitive workload so that controllers are able to simultaneously achieve safe, efficient, and expedient operations at high traffic demand levels.

  17. Substantive Transparency Requirements in International Investment Law

    NARCIS (Netherlands)

    Pohl, Jens Hillebrand

    2017-01-01

    Few concepts in public governance evoke a more positive sentiment than transparency. Whether ultimately grounded in expediency or morality, transparency has emerged out of its municipal origins and been received at the international plane. This article examines the current state of evolution of the

  18. Africa Insight - Vol 39, No 4 (2010)

    African Journals Online (AJOL)

    Political expediency and the rule of law in Africa: A focus on selected cases · EMAIL FULL TEXT EMAIL FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. F Ikome, D Kode. http://dx.doi.org/10.4314/ai.v39i4.54655 ...

  19. An Approach to Ethical Practice in Management and Trainer Training.

    Science.gov (United States)

    Johnston, Rita

    1992-01-01

    Concern with ethics has given rise to two educational approaches, one derived from philosophical principles of social ethics, the other based on case studies of practical issues. A combination of these is necessary to ensure situational applicability and to avoid moral relativism and expediency. (SK)

  20. Concise Synthesis of Thapsigargin from Nortrilobolide

    DEFF Research Database (Denmark)

    Crestey, François; Toma, Maddalena; Christensen, Søren Brøgger

    2015-01-01

    Herein, we wish to describe for the first time an expedient synthesis of the hexaoxygenated guaianolide thapsigargin (1), a potent inhibitor of the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA), from the natural product nortrilobolide (2). This innovative protocol involves three key steps: a on...

  1. On extraction reagents for hydrometallurgy

    International Nuclear Information System (INIS)

    Zolotov, Yu.A.

    1975-01-01

    Fundamental requirements to the extractants are considered. Ways of obtaining selective extractants are discussed in particular on the basis of coordination chemistry achivements. Attention is drawn to expediency of study (as extractants) of flotation reagents, additions to the oil, pesticides, accelerators of caoutchouc vulcanization

  2. Personality Characteristics and Self-Concept of Preservice Teachers Related to Their Pupil Control Orientation.

    Science.gov (United States)

    Halpin, Glennelle; And Others

    1982-01-01

    In a study of teacher trainees' personality characteristics related to pupil control, humanistically oriented educators tended to be emotionally stable, expedient, positive, imaginative, venturesome, relaxed and had high self-concepts. Authoritarian educators were more affected by feelings, conscientious, sober, practical, shy, reserved, tense and…

  3. Estimation of free-flowingmicro hydroelectric power stations in Krasnoyarsk region

    OpenAIRE

    Kachina, E.; Botcharova, E.

    2010-01-01

    The external factors defining expediency of using micro hydroelectric power stations are considered. Exploration of areas of Krasnoyarsk region, which are suitable for usage of micro hydroelectric power stations is carried out. The market of primary real small hydroelectric engineering in Krasnoyarsk region is defined.

  4. Het verband tussen natuurlijke en anthropogene landschapsvormen, bezien vanuit de betrekkingen in grensmilieu’s

    NARCIS (Netherlands)

    Leeuwen, van Chr.G.

    1965-01-01

    The isomorphy of natural and anthropogeneous landscapes with regard to the environmental conditions in border areas The contact in space between opposite situations constitutes two main types of boundaries. The distinction of these two types offers a useful expedient in ecology. It may also clarify

  5. The prospect of the DOE - CNPP bilateral contracts at the decommissioning stage

    International Nuclear Information System (INIS)

    Neretin, Yu.A.

    2002-01-01

    Obviously, the priority is the effective and purposeful consumption of the state accounts and foreign partners' funds at the CNPP decommissioning. Thereupon, it is expedient to use DOE and CNPP bilateral contracts experience in order to provide the decommissioning task performance at the schedule date

  6. PECULIARITIES OF THE TECHNOLOGY OF CONTINUOUS CASTING OF SLUGS OF MACHINE- AND MACHINE-TOOL-BUILDING

    OpenAIRE

    E. B. Demchenko; E. I. Marukovich

    2006-01-01

    The peculiarities of technology of continuous casting of ingots of machine- and machine tool building are shown. At development of technology it is necessary to subject the nomenclature of ingots to analysis in order to reveal expediency of their production by means of continuous casting.

  7. Smoking cue reactivity across massed extinction trials: negative affect and gender effects.

    Science.gov (United States)

    Collins, Bradley N; Nair, Uma S; Komaroff, Eugene

    2011-04-01

    Designing and implementing cue exposure procedures to treat nicotine dependence remains a challenge. This study tested the hypothesis that gender and negative affect (NA) influence changes in smoking urge over time using data from a pilot project testing the feasibility of massed extinction procedures. Forty-three smokers and ex-smokers completed the behavioral laboratory procedures. All participants were over 17 years old, smoked at least 10 cigarettes daily over the last year (or the year prior to quitting) and had expired CO below 10 ppm at the beginning of the ~4-hour session. After informed consent, participants completed 45 min of baseline assessments, and then completed a series of 12 identical, 5-minute exposure trials with inter-trial breaks. Smoking cues included visual, tactile, and olfactory cues with a lit cigarette, in addition to smoking-related motor behaviors without smoking. After each trial, participants reported urge and negative affect (NA). Logistic growth curve models supported the hypothesis that across trials, participants would demonstrate an initial linear increase followed by a decrease in smoking urge (quadratic effect). Data supported hypothesized gender, NA, and gender×NA effects. Significant linear increases in urge were observed among high and low NA males, but not among females in either NA subgroup. A differential quadratic effect showed a significant decrease in urge for the low NA subgroup, but a non-significant decrease in urge in the high NA group. This is the first study to demonstrate gender differences and the effects of NA on the extinction process using a smoking cue exposure paradigm. Results could guide future cue reactivity research and exposure interventions for nicotine dependence. Copyright © 2010 Elsevier B.V. All rights reserved.

  8. Upregulated Expression of a Unique Gene by Hepatitis B x Antigen Promotes Hepatocellular Growth and Tumorigenesis

    Directory of Open Access Journals (Sweden)

    Zhaorui Lian

    2003-05-01

    Full Text Available Hepatitis B x antigen (HBxAg is a trans-activating protein that may be involved in hepatocarcinogenesis, although few natural effectors of HBxAg that participate in this process have been identified. To identify additional effectors, whole cell RNA isolated from HBxAg-positive and HBxAg-negative HepG2 cells were compared by polymerase chain reaction select cDNA subtraction, and one clone, upregulated gene, clone 11 (URG11, was chosen for further characterization. Elevated levels of URG11 mRNA and protein were observed in HBxAg-positive compared to HBxAg-negative HepG2 cells. Costaining was observed in infected liver (P<.01. URG11 stimulated cell growth in culture (P<.01, anchorage-independent growth in soft agar (P<.001, and accelerated tumor formation (P<.01, and yielded larger tumors (P<.02 in SCID mice injected subcutaneously with HepG2 cells. These data suggest that URG11 is a natural effector of HBxAg that may promote the development of hepatocellular carcinoma.

  9. Does Repeated Ticking Maintain Tic Behavior? An Experimental Study of Eye Blinking in Healthy Individuals

    Directory of Open Access Journals (Sweden)

    Daniel J. V. Beetsma

    2013-01-01

    Full Text Available Tics in Tourette Syndrome (TS are often preceded by 'premonitory urges': annoying feelings or bodily sensations. We hypothesized that, by reducing annoyance of premonitory urges, tic behaviour may be reinforced. In a 2X2 experimental design in healthy participants, we studied the effects of premonitory urges (operationalized as air puffs on the eye and tic behaviour (deliberate eye blinking after a puff or a sound on changes in subjective evaluation of air puffs, and EMG responses on the m. orbicularis oculi. The experimental group with air puffs+ blinking experienced a decrease in subjective annoyance of the air puff, but habituation of the EMG response was blocked and length of EMG response increased. In the control groups (air puffs without instruction to blink, no air puffs, these effects were absent. When extrapolating to the situation in TS patients, these findings suggest that performance of tics is reinforced by reducing the subjective annoyance of premonitory urges, while simultaneously preventing habituation or even inducing sensitisation of the physiological motor response.

  10. Benefits of immediate EMDR vs. eclectic therapy intervention for victims of physical violence and accidents at the workplace: a pilot study.

    Science.gov (United States)

    Brennstuhl, Marie-Jo; Tarquinio, Cyril; Strub, Lionel; Montel, Sebastien; Rydberg, Jenny Ann; Kapoula, Zoi

    2013-06-01

    This study focuses on 34 victims of aggression at the workplace, less than 48 hours following the incident of aggression. We compared victims who received an EMDR emergency protocol (URG-EMDR; n = 19) that we developed with those who received a method of intervention called eclectic therapy (n = 15). The results show that URG-EMDR therapy, provided within 48 hours, resulted in a greater decrease in perceived stress and a lower PCL-S score than eclectic therapy did. The scores were lower in both groups after 24 hours, and after 3 months, the drop was significantly greater among the victims treated with the URG-EMDR protocol; none of the EMDR-treated patients exhibited symptoms of posttraumatic stress.

  11. Introducing "Cool School": Where Peace Rules and Conflict Resolution Can Be Fun

    Science.gov (United States)

    Young, Mark; Killen, Melanie; Lee-Kim, Jennie; Park, Yoonjung

    2012-01-01

    The need to play is primeval in human beings, at least as strong as the urge to fight. While the larger gaming community has traditionally focused on the fairly lucrative potential of exploiting the urge to fight in the form of violent and destructive war games, the "Serious Games" segment has become aware of the power of applying this…

  12. Second Generation Electronic Nicotine Delivery System Vape Pen Exposure Generalizes as a Smoking Cue.

    Science.gov (United States)

    King, Andrea C; Smith, Lia J; McNamara, Patrick J; Cao, Dingcai

    2018-01-05

    Second generation electronic nicotine delivery systems (ENDS; also known as e-cigarettes, vaporizers or vape pens) are designed for a customized nicotine delivery experience and have less resemblance to regular cigarettes than first generation "cigalikes." The present study examined whether they generalize as a conditioned cue and evoke smoking urges or behavior in persons exposed to their use. Data were analyzed in N = 108 young adult smokers (≥5 cigarettes per week) randomized to either a traditional combustible cigarette smoking cue or a second generation ENDS vaping cue in a controlled laboratory setting. Cigarette and e-cigarette urge and desire were assessed pre- and post-cue exposure. Smoking behavior was also explored in a subsample undergoing a smoking latency phase after cue exposure (N = 26). The ENDS vape pen cue evoked both urge and desire for a regular cigarette to a similar extent as that produced by the combustible cigarette cue. Both cues produced similar time to initiate smoking during the smoking latency phase. The ENDS vape pen cue elicited smoking urge and desire regardless of ENDS use history, that is, across ENDS naїve, lifetime or current users. Inclusion of past ENDS or cigarette use as covariates did not significantly alter the results. These findings demonstrate that observation of vape pen ENDS use generalizes as a conditioned cue to produce smoking urge, desire, and behavior in young adult smokers. As the popularity of these devices may eventually overtake those of first generation ENDS cigalikes, exposure effects will be of increasing importance. This study shows that passive exposure to a second generation ENDS vape pen cue evoked smoking urge, desire, and behavior across a range of daily and non-daily young adult smokers. Smoking urge and desire increases after vape pen exposure were similar to those produced by exposure to a first generation ENDS cigalike and a combustible cigarette, a known potent cue. Given the increasing

  13. Spatial b-value variations in the Upper Rhine Graben

    Science.gov (United States)

    Barth, A.

    2012-04-01

    The natural seismicity of the Upper Rhine Graben (URG) is of growing interest for science and society, since the management of deep geothermal power plants requires local hazard assessment. The availability of new bulletin data and the combination of catalogues from Germany, France and Switzerland allows us to analyse the spatial changes in the magnitude-frequency distribution along the Graben axis in detail. We derive magnitude conversions between the different bulletins to obtain a uniform earthquake catalogue and decluster the data to extract fore- and aftershocks resulting in a Poissonian event distribution. Since the density of monitoring seismometers has improved over time, we determine several intervals of magnitude completeness. Generally, our catalogue is complete for magnitudes ML ≥ 2.0 since 1982 for the entire URG. To incorporate high magnitude events it is essential to use historic earthquake data. Those magnitudes are estimated by their macroseismic intensity distribution, and thus, they have a high uncertainty compared to instrumental magnitudes. We show that historic earthquake magnitudes are overestimated by 0.4 magnitude units in the URG. We apply a spatial window on the final dataset and move it along the Graben axis. For each set of 50 events we determine local variations of the magnitude frequency distribution after Gutenberg-Richter by a maximum likelihood estimation. The seismicity rate for ML ≥ 2.0 varies between 2 per year per 1000 km2 in the southern URG and 0.2 per year per 1000 km2 in the northern URG. The b-values vary between 0.8 and 1.4 with the highest values around Freiburg, showing a high variability of the magnitude distribution in the URG. Additionally, we examine the hypocentral depth distribution along the Graben, which results in a seismically active upper and lower crust in the southern and northern parts, separated by the central part with missing seismicity in the lower crust. According to the spatial distribution of b

  14. Implementation of a High-Performance Cardiopulmonary Resuscitation Protocol at a Collegiate Emergency Medical Services Program

    Science.gov (United States)

    Stefos, Kathryn A.; Nable, Jose V.

    2016-01-01

    Out-of-hospital cardiac arrest (OHCA) is a significant public health issue. Although OHCA occurs relatively infrequently in the collegiate environment, educational institutions with on-campus emergency medical services (EMS) agencies are uniquely positioned to provide high-quality resuscitation care in an expedient fashion. Georgetown University's…

  15. Terminological problems in radiation diagnosis

    International Nuclear Information System (INIS)

    Rozenfel'd, L.G.

    1991-01-01

    It was noted the necessity of regulation of medical termonilogy. The introduction of terms radiation diagnosis, radiation therapy was justified, usage of terms xeroroentgenography, reconstructive tomography was recommended. In author's opinion it was expedient to exclude from utilization the terms diagnostic radiology, skiagraphy, electroroentgenography, computerized tomography

  16. IMPROVING OF THE ORGANIZATION OF INNOVATION MANAGEMENT OF THE BUILDING ENTERPRISE

    Directory of Open Access Journals (Sweden)

    A. G. Magomedov

    2015-01-01

    Full Text Available The article is devoted to improving the organization of innovative activity management of construction enterprises. Proposed a sequence of actions for improving the management of innovation, substantiated expediency of the use of such institutional innovation management as intrapreneurship and centers of subcontracting. 

  17. Support system of electronic health cards

    Directory of Open Access Journals (Sweden)

    Yu. L. Nechiporenko

    2013-02-01

    Full Text Available Made the survey online sources regarding the specification of functions of systems support electronic medical records. Given the tendency to attract mobile devices to conduct an array of medical data expedient development of EHR, which can be installed on a personal mobile device.

  18. Het opportuniteitsbeginsel en het recht van de Europese Unie : een onderzoek naar de betekenis van strafvorderlijke beleidsvrijheid in de geëuropeaniseerde rechtsorde

    NARCIS (Netherlands)

    Geelhoed, Willem

    2013-01-01

    The law of the European Union requires effective enforcement of EU policy, for which criminal law can, and sometimes must be used. This means that the scope of policy freedom that criminal law authorities can utilize, varies dependent on the applicable legal context. The principle of expediency,

  19. Development and Evaluation of HawkLearn: A Next Generation Learning Management System

    Science.gov (United States)

    Round, Kimberlee L.

    2013-01-01

    Cloud-based computing in higher education has the potential to impact institutions on a myriad of fronts, including technology governance, flexibility, financial, and intellectual property. As the demand for blended and online education increases, institutions are considering expedient approaches to implementing learning management systems (LMSs).…

  20. Eliciting the challenges and opportunities organizations face when delivering open online education: A group-concept mapping study

    NARCIS (Netherlands)

    Schophuizen, Martine; Kreijns, Karel; Stoyanov, Slavi; Kalz, Marco

    2017-01-01

    The global attention for open online education (OOE) caused a situation in which higher education institutions (HEIs) reconsider the way they deliver education to the population. With a funding policy, the Dutch Government aims to stimulate OOE in HEIs. The goal is to create more expedient,

  1. Kansen en uitdagingen voor open online onderwijs en implicaties voor de organisatorische inrichting van Nederlandse hoger onderwijs instellingen

    NARCIS (Netherlands)

    Schophuizen, Martine; Kreijns, Karel; Stoyanov, Slavi; Kalz, Marco

    2017-01-01

    The global attention for open online education (OOE) caused a situation in which higher education institutions (HEIs) reconsider the way they deliver education to the population. With a funding policy, the Dutch Government aims to stimulate OOE in HEIs. The goal is to create more expedient,

  2. Organizational challenges and opportunities for Open Online Education: Results of a group-concept mapping study

    NARCIS (Netherlands)

    Schophuizen, Martine; Kreijns, Karel; Stoyanov, Slavi; Kalz, Marco

    2017-01-01

    The global attention for open online education (OOE) caused a situation in which higher education institutions (HEIs) reconsider the way they deliver education to the population. With a funding policy, the Dutch Government aims to stimulate OOE in HEIs. The goal is to create more expedient,

  3. Quantification of Salmonella Survival and Infection in an In vitro Model of the Human Intestinal Tract as Proxy for Foodborne Pathogens.

    NARCIS (Netherlands)

    Wijnands, Lucas M; Teunis, Peter F M; Kuijpers, Angelina F A; Delfgou-Van Asch, Ellen H M; Pielaat, Annemarie

    2017-01-01

    Different techniques are available for assessing differences in virulence of bacterial foodborne pathogens. The use of animal models or human volunteers is not expedient for various reasons; the use of epidemiological data is often hampered by lack of crucial data. In this paper, we describe a

  4. How moral disagreement may ground principled moral compromise

    DEFF Research Database (Denmark)

    Kappel, Klemens

    2018-01-01

    In an influential article, Simon C. May forcefully argued that, properly understood, there can never be principled reasons for moral compromise (May, 2005). While there may be pragmatic reasons for compromising that involve, for instance, concern for political expediency or for stability, there a......In an influential article, Simon C. May forcefully argued that, properly understood, there can never be principled reasons for moral compromise (May, 2005). While there may be pragmatic reasons for compromising that involve, for instance, concern for political expediency or for stability......, there are properly speaking no principled reasons to compromise. My aim in the article is to show how principled moral compromise in the context of moral disagreements over policy options is possible. I argue that when we disagree, principled reasons favoring compromises or compromising can assume a more significant...... part of what makes a position all things considered best, and in this way disagreement can ground moral compromise....

  5. Ampliando o conhecimento sobre a flora fanerogâmica do Ceará

    Directory of Open Access Journals (Sweden)

    Iracema Bezerra Loiola

    2014-10-01

    Full Text Available A pesquisa teve como objetivo geral conhecer, descrever e atualizar a distribuição geográfica dos representantes de Cactaceae, Capparaceae, Combretaceae e Erythroxylaceae ocorrentes no estado do Ceará. Para a coleta de amostras botânicas foram realizadas, no período de 2011 a 2013, quatro expedições de campo em 24 municípios pré-selecionados. Cada expedição teve duração de cinco dias e a participação de cinco componentes. As coleções foram depositadas no herbário EAC e duplicatas distribuídas a herbários nacionais. Os principais resultados obtidos foram: ampliação do número de coleções georreferenciadas e identificadas corretamente; produção de artigos sobre a flora cearense e descrição de uma nova espécie de Erythroxylum (Erythroxylaceae.

  6. Camouflage, Concealment, and Decoys

    Science.gov (United States)

    2010-11-26

    otherwise dull Note. Use canned milk or powdered eggs to increase the binding properties of field-expedient paints. RADAR-ABSORBING MATERIAL 3-72. RAM... falsification of evidence, inducing him to react in a manner prejudicial to his interests. decoy An imitation in any sense of a person, an object

  7. Capital Punishment: An International Perspective.

    Science.gov (United States)

    Kaufman, Edy

    1983-01-01

    The debate over the death penalty in the United States has implications beyond our borders. Because of the lack of universal standards governing its use, only those countries which have abolished capital punishment may, with any moral authority, denounce its exploitation as an instrument of political expediency. (IS)

  8. Adaptation of Rural and Foreign Workers to Industry, International Joint Seminar (Wiesbaden, December 10-13, 1963). Final Report. International Seminars 1963-4.

    Science.gov (United States)

    Organisation for Economic Cooperation and Development, Paris (France). Social Affairs Div.

    The major purpose of a seminar held in Wiesbaden, Germany, was to exchange experiences and views on the methods of expediating adjustment of rural and foreign workers to industry. Major presentations for discussion were "Internal Migration" by Magda Talamo, and "International Migration" by Elie Dimitras. Some conclusions were:…

  9. Comparative Analysis of Pedagogical Technologies in the Context of Future Agrarians' Multicultural Education in the USA

    Science.gov (United States)

    Kravets, Ruslan

    2015-01-01

    In the article the comparative analysis of pedagogical technologies in the USA has been carried out in the context of future agrarians' multicultural education. The essence of traditional and innovative pedagogical technologies and the peculiarities of their realization at higher educational establishments have been viewed. The expediency of…

  10. Candlestick and Faces: Aspects of Lifelong Learning.

    Science.gov (United States)

    Hunt, Cheryl

    1999-01-01

    Government policies view lifelong learning in terms of economic development. A SWOT (strengths, weaknesses, opportunities, threats) analysis of the environment of British community education councils revealed other views of lifelong learning: it takes time and political expediency and national policy can adversely affect what and how people learn.…

  11. Decolonizing the curriculum

    DEFF Research Database (Denmark)

    Lassen, Inger Marie; Jensen, Iben

    2018-01-01

    This article presents a case-based study in which we explore how experience with PBL in Danish universities seems to work in a Ugandan context and whether it is expedient and possible to translate pedagogical approaches from one context to another? Funded by the Danish Development Agency, Danida,...

  12. Некоторые вопросы эколого социальной обстановки в Тамбове и области. 2002 год

    OpenAIRE

    Вигдорович, В.; Пантелеев, О.

    2003-01-01

    The official data on the ecological situation in Tambov City and Region is critically analysed in the article. It contains an account of the authors` own point of view and their own experimental results. The evaluation of the expediency of some ecological steps including ecological situation of the population.

  13. Recirculator "SALO" - A basis for creation of a model of sub-critical reactor controlled by the accelerator

    NARCIS (Netherlands)

    Gann, V.V.; Guk, I.S.; Dovbnya, A.N.; Kononenko, S.G.; Kostromin, A.S.; Peev, F.A.; Prochorets, I.M.; Soldatov, C.A.; Tarasenko, A.S.; Wiel, van der M.J.; Botman, J.I.M.

    2006-01-01

    Recently opportunities of creation test facility with sub-crit. reactors controlled by accelerators of particles are actively discussed. At an initial stage of these researches it is the most expedient to use electron accelerators as cost of such facility will be much less, than at use of proton

  14. The Role of Vegetative Dysfunction and Its Correction in Gastroesophageal Reflux Disease

    Directory of Open Access Journals (Sweden)

    G.V. Osyodlo

    2014-04-01

    Full Text Available The article analyzes the findings regarding the effect of vegetative dysfunction on the course of gastroesophageal reflux disease, the expediency of autonomic imbalance correction by phenibut on the background of antisecretory therapy with pantoprazole is shown, it helps to improve the immediate and long-term results.

  15. Psychological and pedagogical grounds for applying communicative method of teaching foreign languages in higher school with the purpose of realization of students professional orientation

    OpenAIRE

    Yavoruk, O.; Gridneva, S.

    2010-01-01

    The article deals with the notion of “professional orientation”, its components and levels. The principles of communicative method of teaching foreign languages are analyzed from psychological and pedagogical point of view. Expediency of applying the given method with the purpose of realization of students’ professional orientation is substantiated.

  16. Flood-Fighting Structures Demonstration and Evaluation Program: Laboratory and Field Testing in Vicksburg, Mississippi

    Science.gov (United States)

    2007-07-01

    then it should be disposed of by recycling or land-filling. This material should not be burned due to the formation of carbon dioxide and carbon...and 2-192). A top spreader bar Chapter 2 Laboratory Testing and Evaluation of Expedient Flood-fighting Barriers 135 Figure 2-189

  17. Information needs: Perceived and real for state decisionmakers

    Science.gov (United States)

    Schwartz, A. R.; Spirou, C.; Kier, W.; Tetley, M.

    1975-01-01

    Remote sensing techniques provide important information for land and water use planning organizations in order to assess coastal developments and their impact on water resources, sediment transport, erosion, and marine biology. Political expediency requires pertinent data acquisition and data dissemination to local populations for coastal zone management decision making.

  18. The Decision to Form the Kangan Committee--A Case Study in the Educational Policy Process.

    Science.gov (United States)

    Ford, John

    1983-01-01

    The postsecondary education policymaking process in Australia, rather than being goal-oriented and rational, is a series of adjustments to existing policy dictated by political expediency, often over many years and changes of government and leading to decisions reflecting unstable origins. This committee's broad influences illustrate this process.…

  19. O processo comunicativo no serviço de atendimento móvel de urgência (SAMU-192 Proceso de comunicación en el servicio de emergencia móvil (SAMU/192 Communicative process in the mobile emergency service (SAMU/192

    Directory of Open Access Journals (Sweden)

    Maria Claudia dos Santos

    2012-03-01

    Full Text Available Este trabalho objetiva caracterizar o processo comunicativo entre os auxiliares de enfermagem das viaturas de Suporte Básico de Vida do Serviço de Atendimento Móvel de Urgência, a coordenação deste serviço e a Central Única de Regulação Médica de um município do Estado de São Paulo. Trata-se de uma pesquisa descritivo-qualitativa que utilizou a análise temática de conteúdo para a análise dos dados. Usou-se entrevista semi-estruturada para a coleta de dados que foi realizada em janeiro de 2010. Os resultados obtidos mostram dificuldades de comunicação tanto com a Central de Regulação Médica quanto com a coordenação. Os aspectos que mais se destacaram foram as falhas durante a transmissão via rádio, falta de capacitação dos operadores de rádio, acesso à coordenação dificultado e ausência da supervisão dos enfermeiros. No entanto, foi possível detectar soluções que visam à melhoria da comunicação e, consequentemente, do atendimento ofertado pelo Serviço de Atendimento Móvel de Urgência.Este estudio objetivó caracterizar la comunicación entre los auxiliares de enfermería que trabajan en los vehículos de Soporte Básico de Vida del Servicio de Emergencia Móvil, la coordinación del servicio y la Central Única de Reglamento Médico en un municipio de São Paulo, Brasil. Este estudio descriptivo-cualitativo utilizó el análisis temático de contenido para el análisis de datos. Se utilizaron entrevistas semi-estructuradas para recopilar los datos que se realizaron en enero de 2010. Los resultados muestran las dificultades en la comunicación tanto con la Central de Reglamento Médico como con la coordinación. Entre los aspectos que más se destacaron están los errores durante la transmisión de radio, falta de capacitación de los peradores de radio, acceso dificultado a la coordinación y falta de supervisión de los enfermeros. Sin embargo, fue posible detectar soluciones que tienen como objetivo

  20. Drive for thinness, affect regulation and physical activity in eating disorders: a daily life study.

    Science.gov (United States)

    Vansteelandt, Kristof; Rijmen, Frank; Pieters, Guido; Probst, Michel; Vanderlinden, Johan

    2007-08-01

    Using Ecological Momentary Assessment, the within patient associations between drive for thinness, emotional states, momentary urge to be physically active and physical activity were studied in 32 inpatients with an eating disorder. Participants received an electronic device and had to indicate at nine random times a day during 1 week their momentary drive for thinness, positive and negative emotional states and their urge to be physically active and physical activity. Multilevel analyses indicated that patients with higher mean levels for urge to be physically active were characterized by lower body mass index (BMI) and chronically negative affect whereas patients with higher mean levels for physical activity were characterized by lower BMI and higher dispositions for drive for thinness. In addition, within patient relations between drive for thinness and urge to be physically active were moderated by BMI and chronically negative affect whereas within patient relations between drive for thinness and physical activity were moderated by BMI. Finally, also positive emotional states were significantly associated with physical activity within patients. By using a daily process design, characteristics of physical activity were revealed that have not been identified with assessment methods that have a lower time resolution.

  1. Augmentation with naltrexone to treat compulsive sexual behavior: a case series.

    Science.gov (United States)

    Raymond, Nancy C; Grant, Jon E; Coleman, Eli

    2010-02-01

    Compulsive sexual behavior (CSB) is generally characterized by recurrent and intense sexually arousing fantasies, sexual urges, and behaviors, which cause individuals distress or impair daily functioning. Descriptive studies of individuals with paraphilic and nonparaphilic CSB indicate that they experience urges to engage in problematic sexual behavior. The opiate antagonist naltrexone has been successfully used to treat a number of disorders in which urges to engage in problematic behavior are a central feature, such as alcoholism. We hypothesized that naltrexone would reduce the urges and behaviors associated with CSB. Records of 19 male patients with CSB who were treated with naltrexone at an outpatient adult sexual health clinic were retrospectively reviewed. Nearly all patients were already taking other psychotropic medications when naltrexone was initiated. Seventeen (89%) of the 19 patients reported a reduction in CSB symptoms when taking naltrexone for a period ranging from 2 months to 2.3 years, as judged by Clinical Global Impression scores of 1 or 2, indicating "very much improved" or "much improved." Five (26%) of the 19 patients chose to discontinue the medication. Naltrexone may be a useful adjunctive treatment for CSB.

  2. Tourette Syndrome: Update.

    Science.gov (United States)

    Hallett, Mark

    2015-08-01

    Tourette Syndrome is a disorder characterized by tics. It typically begins in childhood and often improves in adult life. Tics are best described as voluntary movements made automatically so that volition is not ordinarily appreciated. There is frequently an urge, sometimes in the form of a specific sensory feeling (sensory tic), that precedes the tic. Patients say that they make the tic in order to reduce the urge, although shortly after the tic, the urge recurs. The sensory feeling may arise due to defective sensory habituation. Since tics relieve the urge, this can be considered rewarding, and repetition of this behavior may perpetuate the tic as a habit. Tourette Syndrome affects boys more than girls and is associated with attention deficit hyperactivity disorder and obsessive compulsive disorder. Although Tourette Syndrome often appears to be autosomal recessive in inheritance, it has been difficult to find any abnormal genes. There is a loss of inhibition in these patients and recent studies show abnormalities in brain GABA. Certainly there is also an abnormality in dopamine function and dopamine blocking agents are effective therapy. In severe drug-refractory patients, deep brain stimulation can be effective. Published by Elsevier B.V.

  3. Expedient Method for Samarium(II) Iodide Preparation Utilizing a Flow Approach

    Czech Academy of Sciences Publication Activity Database

    Voltrová, Svatava; Šrogl, Jiří

    2013-01-01

    Roč. 24, č. 3 (2013), s. 394-396 ISSN 0936-5214 R&D Projects: GA MŠk LH12013 Institutional support: RVO:61388963 Keywords : flow * samarium * iodide * reduction Subject RIV: CC - Organic Chemistry Impact factor: 2.463, year: 2013

  4. EDITORIAL: Ongoing climatic change in Northern Eurasia: justification for expedient research

    Science.gov (United States)

    Groisman, Pavel; Soja, Amber J.

    2009-12-01

    A brief overview of the ongoing climatic and environmental changes in Northern Eurasia serves as an editorial introduction to this, the second, special Northern Eurasia Earth Science Partnership Initiative (NEESPI) focus issue of Environmental Research Letters. Climatic changes in Northern Eurasia over the last hundred years are reflected in numerous atmospheric and terrestrial variables. Many of these are noticeably significant above the confidence level for 'weather' or other (fire regime, ecosystem change) noise and thus should be further investigated in order to adapt to their impacts. In this focus issue, we introduce assorted studies of different aspects of contemporary change in Northern Eurasia. Most of these have been presented at one of the NEESPI workshops (for more information see neespi.org) and/or American Geophysical Union and European Geosciences Union NEESPI open sessions during the past year. These studies are diverse, representing the diversity of climates and ecosystems across Northern Eurasia. Some of these are focused on smaller spatial scales and/or address only specific aspects of the global change implications across the subcontinent. But the feeling (and observational evidence) that these changes have already been quite rapid and can have global implications inspires us to bring this suite of papers to the readers' attention. See the PDF for the full text of the editorial. Focus on Climatic and Environmental Change in Northern Eurasia Contents Preface Northern Eurasia Earth Science Partnership Initiative Pavel Groisman and Amber J Soja Editorial Siberia integrated regional study: Multidisciplinary investigations of interrelation between Siberia environment dynamics and global climate change E P Gordov and E A Vaganov Studies of the energy and water cycles in Northern Eurasia Comparison and evaluation of gridded radiation products across northern Eurasia T J Troy and E F Wood Reanalysis data underestimate significant changes in growing season weather in Kazakhstan C K Wright, K M de Beurs, Z K Akhmadieva, P Y Groisman and G M Henebry Climate change in Inner Mongolia from 1955 to 2005—trends at regional, biome and local scales N Lu, B Wilske, J Ni, R John and J Chen Application of the Snowmelt Runoff model in the Kuban river basin using MODIS satellite images M V Georgievsky Record Russian river discharge in 2007 and the limits of analysis A I Shiklomanov and R B Lammers Paleoclimatic reconstructions for the south of Valdai Hills (European Russia) as paleo-analogs of possible regional vegetation changes under global warming E Novenko, A Olchev, O Desherevskaya and I Zuganova Diagnosis of the record discharge of Arctic-draining Eurasian rivers in 2007 Michael A Rawlins, Mark C Serreze, Ronny Schroeder, Xiangdong Zhang and Kyle C McDonald Studies of the cryosphere in Northern Eurasia Groundwater storage changes in arctic permafrost watersheds from GRACE and in situ measurements Reginald R Muskett and Vladimir E Romanovsky Changes in snow cover over Northern Eurasia in the last few decades O N Bulygina, V N Razuvaev and N N Korshunova Modeling sub-sea permafrost in the East Siberian Arctic Shelf: the Dmitry Laptev Strait D Nicolsky and N Shakhova Snow cover basal ice layer changes over Northern Eurasia since 1966 Olga N Bulygina, Pavel Ya Groisman, Vyacheslav N Razuvaev and Vladimir F Radionov Snow cover and permafrost evolution in Siberia as simulated by the MGO regional climate model in the 20th and 21st centuries I M Shkolnik, E D Nadyozhina, T V Pavlova, E K Molkentin and A A Semioshina Studies of the biosphere in Northern Eurasia The influence of regional surface soil moisture anomalies on forest fires in Siberia observed from satellites A Bartsch, H Balzter and C George Change and persistence in land surface phenologies of the Don and Dnieper river basins V Kovalskyy and G M Henebry Effects of climatic changes on carbon dioxide and water vapor fluxes in boreal forest ecosystems of European part of Russia A Olchev, E Novenko, O Desherevskaya, K Krasnorutskaya and J Kurbatova The effects of climate, permafrost and fire on vegetation change in Siberia in a changing climate N M Tchebakova, E Parfenova and A J Soja An image-based inventory of the spatial structure of West Siberian wetlands A Peregon, S Maksyutov and Y Yamagata Modeling of the carbon dioxide fluxes in European Russia peat bogs J Kurbatova, C Li, F Tatarinov, A Varlagin, N Shalukhina and A Olchev Feedbacks of windthrow for Norway spruce and Scots pine stands under changing climate O Panferov, C Doering, E Rauch, A Sogachev and B Ahrends Reconstruction and prediction of climate and vegetation change in the Holocene in the Altai-Sayan mountains, Central Asia N M Tchebakova, T A Blyakharchuk and E I Parfenova Simulating the effects of soil organic nitrogen and grazing on arctic tundra vegetation dynamics on the Yamal Peninsula, Russia Qin Yu, Howard Epstein and Donald Walker Possible decline of the carbon sink in the Mongolian Plateau during the 21st century Y Lu, Q Zhuang, G Zhou, A Sirin, J Melillo and D Kicklighter The frequency of forest fires in Scots pine stands of Tuva, Russia G A Ivanova, V A Ivanov, E A Kukavskaya and A J Soja Lateral extension in Sphagnum mires along the southern margin of the boreal region, Western Siberia A Peregon, M Uchida and Y Yamagata Evaluating the sensitivity of Eurasian forest biomass to climate change using a dynamic vegetation model J K Shuman and H H Shugart Studies of socioeconomic processes in Northern Eurasia Comparing patterns of ecosystem service consumption and perceptions of range management between ethnic herders in Inner Mongolia and Mongolia L Zhen, B Ochirbat, Y Lv, Y J Wei, X L Liu, J Q Chen, Z J Yao and F Li Land cover/land use change in semi-arid Inner Mongolia: 1992-2004 Ranjeet John, Jiquan Chen, Nan Lu and Burkhard Wilske Spatial and temporal patterns of greenness on the Yamal Peninsula, Russia: interactions of ecological and social factors affecting the Arctic normalized difference vegetation index D A Walker, M O Leibman, H E Epstein, B C Forbes, U S Bhatt, M K Raynolds, J C Comiso, A A Gubarkov, A V Khomutov, G J Jia, E Kaarlejarvi, J O Kaplan, T Kumpula, P Kuss, G Matyshak, N G Moskalenko, P Orekhov, V E Romanovsky, N G Ukraientseva and Q Yu Methods of surface monitoring from space A bio-optical algorithm for the remote estimation of the chlorophyll-a concentration in case 2 waters Anatoly A Gitelson, Daniela Gurlin, Wesley J Moses and Tadd Barrow Estimation of chlorophyll-a concentration in case II waters using MODIS and MERIS data—successes and challenges W J Moses, A A Gitelson, S Berdnikov and V Povazhnyy Dual scale trend analysis for evaluating climatic and anthropogenic effects on the vegetated land surface in Russia and Kazakhstan K M de Beurs, C K Wright and G M Henebry Satellite microwave remote sensing of North Eurasian inundation dynamics: development of coarse-resolution products and comparison with high-resolution synthetic aperture radar data R Schroeder, M A Rawlins, K C McDonald, E Podest, R Zimmermann and M Kueppers

  5. Evaluation of Expedient Decontamination Options with Activated Peroxide-based Liquid Sporicides

    Science.gov (United States)

    2013-02-05

    Figure 2-1) that are typical of the materials found in residential dwellings and meet industry standards or specifications for indoor use. Documented...Anthrax inhalation and lethal human infection. Lancet, 2002. 359(9307): p. 710-1. 14. Glassman, H.N., Industrial inhalation anthrax. Bacteriol. Rev...Begin by donning PPE (gloves, lab coat, and protective eyewear ). 2. Clean the workspace by wiping with pAB, next with DI water , and lastly with a 70

  6. Anti-coal export strategy. Expedient in terms of global climate protection?

    International Nuclear Information System (INIS)

    Umbach, Frank

    2016-01-01

    The German Environment Ministry had joined in the summer of 2014 the European and American trend, to stop in future the total financial support for the technology export of coal power plants. This disinvestment movement considerable face the opposition especially in developing countries, which are offered alternatives mainly on Chinese investment. In addition to the resulting far-reaching economic implications for Western companies, this development has an increasing expiry of the geopolitical influence of Europe and the United States to follow. Furthermore speak climate policy reasons against the end of the export credit financing. Overall, this development, prevents to achieve the widely shared climate policy goals because a lot of new and existing capacities can not be realized on the latest state of the art. [de

  7. Expedient Access to an N-phenylpyrrolidin-2-yl Heterocycle via a ...

    African Journals Online (AJOL)

    NICO

    Milder bases were employed catalytically for the 1,4-conjugate addition of ... using 2-bromoaniline given that it was available in our labora- tory and ... Scheme 3. Base-catalysed intramolecular aza-Michael reaction of indoles containing pendant-conjugated esters. Scheme 4. Synthesis of pyran-2-ol. Scheme 5. Synthesis of ...

  8. A facile and expedient one-pot three-component reaction leading to ...

    Indian Academy of Sciences (India)

    A three-component reaction between triphenylphosphine, a dialkyl acetylenedicarboxylate and phthalazin-1(2H)-ones that affords novel organic phosphorane derivatives in good to excellent yields is reported. FTIR, 1H, 13C and 31P NMR and elemental analyses have been utilized to characterize the synthesized ...

  9. INTERNAL CONTROL OF INVESTMENT PROJECTS

    Directory of Open Access Journals (Sweden)

    Yu. N. Yudenkov

    2010-01-01

    Full Text Available Estimation and technics of the account of expenses, efficiency, financial result should enter into the list of regular checks from service of internal control that demands corresponding vocational training of internal controlers which should own methods of an estimation of expediency of acquisition of long-term actives.

  10. Proposing an Evaluation Framework for Interventions: Focusing on Students' Behaviours in Interactive Science Exhibitions

    Science.gov (United States)

    Hauan, Nils Petter; DeWitt, Jennifer; Kolstø, Stein Dankert

    2017-01-01

    Materials designed for self-guided experiences such as worksheets and digital applications are widely used as tools to enable interactive science exhibitions to support students' progress towards conceptual understanding. However, there is a need to find expedient ways to evaluate the quality of educational experiences resulting from the use of…

  11. KTA nuclear safety rules, or the love for service according to the rules

    International Nuclear Information System (INIS)

    Sauer, G.W.

    1993-01-01

    This paper presents some critical comments on the question as to what extent the KTA rules really support the safety-oriented and in this sense purposeful implementation of the Atomic Energy Act. The authors review some specific KTA rules for their expediency, not with holding disapproval in some cases. (HP) [de

  12. 40 CFR 261.151 - Wording of the instruments.

    Science.gov (United States)

    2010-07-01

    ..., Therefore, the Grantor and the Trustee agree as follows: Section 1. Definitions. As used in this Agreement... the validity or expediency of any such sale or other disposition; (b) To make, execute, acknowledge..., and the amount of insurance for all facilities covered, which must total the face amount shown below...

  13. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Role of vanadium and pyridine in heteropolycompounds for selective oxidation of ... in the selective oxidation of aromatic methyl group to aldehyde without mediators .... ion recognition studies of lower rim 1,3-di{rhodamine} conjugate of calix[4]arene ... Two expedient one-pot methods have been developed for synthesis of ...

  14. WOLFRAMALPHA use when training in the solution of tasks with parameters

    Directory of Open Access Journals (Sweden)

    Дмитрий Анатольевич Власов

    2014-12-01

    Full Text Available In the center of attention of this article WolframAlpha — quality of mathematical and methodical preparation of future mathematics teacher and informatics in bachelor degree and magistracy system is essential to raise the new mathematical online-processor allowing on condition of methodically expedient use in educational process.

  15. Versions of tubes combining for ionization `spaghetti`-calorimeter; Varianty ob``edineniya trubok ionizatsionnogo `spagetti`-kalorimetra

    Energy Technology Data Exchange (ETDEWEB)

    Misyura, S P; Smol` , A V

    1994-12-31

    The theoretical analysis of some electrical schemes of tubes combining intended for ionization `spaghetti`-calorimeter is presented. The expediency of the parallel tubes connection is shown for all schemes being considered. The restrictions for the parameters of scheme elements (blocking capacitors, matching transformer etc.) have been deduced. 10 refs., 23 figs.

  16. Information Technologies of the Distributed Applications Design

    Directory of Open Access Journals (Sweden)

    Safwan Al SALAIMEH

    2007-01-01

    Full Text Available The questions of distributed systems development based on Java RMI, EJB and J2EE technologies and tools are rated. Here is brought the comparative analysis, which determines the domain of an expedient demand of the considered information technologies as applied to the concrete distributed applications requirements.

  17. Usage of patriotic motives in promotion of products in markets

    Directory of Open Access Journals (Sweden)

    Bozhkova Viktoriia Viktorivna

    2015-12-01

    Full Text Available In the article the patriotic motives essence in the appeals of manufacturers has been analyzed; the classification of means, which can be used in the appeals with patriotic implication, has been proposed; the directions of justification of expediency of patriotic motives usage for manufacturers have been defined.

  18. The inherent contradictions in data protection law

    DEFF Research Database (Denmark)

    Blume, Peter Erik

    2012-01-01

    . • Transparency is seen as important and through an information policy, real transparency may be achieved. • Another issue concerns whether it is expedient that the same data protection rules apply to the private and to the public sector. Having separate rules should be considered, as this would give the rules...

  19. School-Based Decision-Making: The Canadian Perspective.

    Science.gov (United States)

    Peters, Frank

    1997-01-01

    In Canada, school-based decision making is a political expedient to co-opt public support for public education at the same time as financial resources to schools are being curtailed. School councils are advisory in nature and have no statutory position in either school or school-system decisions. (17 references) (MLF)

  20. An Evaluation of UNESCO Publications on Mathematics Education: From 1989 to 2013

    Science.gov (United States)

    Yaman, Hakan; Dündar, Sefa; Ayvaz, Ülkü

    2015-01-01

    The word "UNESCO" was created by being taken the initials of "United Nations Educational, Scientific and Cultural Organization". UNESCO has undertaken two main objectives as it can be understood from the name of the organization. This organization is an international organization that works for the expedience of the world in…

  1. Electro-spark machining of cadmium antimonide

    International Nuclear Information System (INIS)

    Ivanovskij, V.N.; Stepakhina, K.A.

    1975-01-01

    Experimental data on electrical erosion of the semiconductor material (cadmium antimonide) alloyed with tellurium are given. The potentialisies and expediency of using the electric-spark method of cutting cadmium antimonide ingots with the resistivity of 1 ohm is discussed. Cutting has been carried out in distilled water and in the air

  2. Evaluation of Imidacloprid-Treated Traps as an Attract and Kill System for Filth Flies During Contingency Settings

    Science.gov (United States)

    2013-04-01

    the metallic green histerid beetle (Saprinus sp.), which was likely attracted to the fermenting combina- tion of attractant and fl ies inside the...stable fl ies on dairy farms. J Agric Entomol. 1993;10:9-19. Geden CJ, Szumlas DE, Walker TW. Evaluation 6. of commercial and fi eld-expedient baited

  3. Screening for diabetes mellitus in a Nigerian family practice population

    African Journals Online (AJOL)

    Background Diabetes mellitus is a non-communicable disease with a rising prevalence worldwide. Most of the increase in prevalence is projected to be in the developing countries. As it is recognised that the onset of the disease and its complications predate the symptoms, it is expedient that screening procedures are ...

  4. Adaptive guard channel allocation scheme with buffer for mobile ...

    African Journals Online (AJOL)

    The devastating effect congestion has on the quality of service delivery and overall network performance demands an utmost attention. This certainly calls for taking some expedient measures to deal with congestion so as to salvage the network from total collapse. In this paper, an adaptive guard channel allocation scheme ...

  5. English Language Teaching and the Promotion of Academic Ethics

    Science.gov (United States)

    Ntombela, Berrington

    2011-01-01

    Institutions of higher learning carry a burden of inculcating a culture of academic ethical behaviour among students as part of their responsibility to produce citizens of high calibre. In fact, this burden is more expedient and pronounced because of aberrant behaviours such as cheating that can potentially affect institutions' credibility. This…

  6. Development of a Virtual Reality Coping Skills Game to Prevent Post-Hospitalization Smoking Relapse in Tobacco Dependent Cancer Patients.

    Science.gov (United States)

    Krebs, Paul; Burkhalter, Jack; Lewis, Shireen; Hendrickson, Tinesha; Chiu, Ophelia; Fearn, Paul; Perchick, Wendy; Ostroff, Jamie

    2009-08-01

    Many hospitalized smokers return to smoking after hospital discharge even though continued smoking can compromise treatment effectiveness, reduce survival, increase risk of disease recurrence, and impair quality of life. After leaving a smoke-free hospital, patients encounter smoking cues at home, such as family members who smoke or emotional triggers such as stress, which can elicit powerful urges to smoke and lead to smoking relapse. Enabling smokers to experience such urges in a controlled setting while providing the ability to practice coping skills may be a useful strategy for building quitting self-efficacy. We are developing a virtual reality coping skills (VRCS) game to help hospitalized smokers practice coping strategies to manage these triggers in preparation for returning home after hospitalization. Our multidisciplinary team developed a prototype VRCS game using Second Life, a platform that allowed rapid construction of a virtual reality environment. The prototype contains virtual home spaces (e.g., living room, kitchen) populated with common triggers to smoke and a "toolkit" with scripted actions that enable the avatar to rehearse various coping strategies. Since eliciting and managing urges to smoke is essential to the game's utility as an intervention, we assessed the ability of the prototype virtual environment to engage former smokers in these scenarios. We recruited eight former smokers with a recent history of hospitalization and guided each through a VRCS scenario during which we asked the patient to evaluate the strength of smoking urges and usefulness of coping strategies. Initial data indicate that patients report high urges to smoke (mean = 8.8 on a 10 point scale) when their avatar confronted virtual triggers such as drinking coffee. Patients rated virtual practice of coping strategies, such as drinking water or watching TV, as very helpful (mean = 8.4 on a 10 point scale) in reducing these urges. With further development, this VRCS game

  7. A multi-dimensional analysis of the upper Rio Grande-San Luis Valley social-ecological system

    Science.gov (United States)

    Mix, Ken

    The Upper Rio Grande (URG), located in the San Luis Valley (SLV) of southern Colorado, is the primary contributor to streamflow to the Rio Grande Basin, upstream of the confluence of the Rio Conchos at Presidio, TX. The URG-SLV includes a complex irrigation-dependent agricultural social-ecological system (SES), which began development in 1852, and today generates more than 30% of the SLV revenue. The diversions of Rio Grande water for irrigation in the SLV have had a disproportionate impact on the downstream portion of the river. These diversions caused the flow to cease at Ciudad Juarez, Mexico in the late 1880s, creating international conflict. Similarly, low flows in New Mexico and Texas led to interstate conflict. Understanding changes in the URG-SLV that led to this event and the interactions among various drivers of change in the URG-SLV is a difficult task. One reason is that complex social-ecological systems are adaptive, contain feedbacks, emergent properties, cross-scale linkages, large-scale dynamics and non-linearities. Further, most analyses of SES to date have been qualitative, utilizing conceptual models to understand driver interactions. This study utilizes both qualitative and quantitative techniques to develop an innovative approach for analyzing driver interactions in the URG-SLV. Five drivers were identified for the URG-SLV social-ecological system: water (streamflow), water rights, climate, agriculture, and internal and external water policy. The drivers contained several longitudes (data aspect) relevant to the system, except water policy, for which only discreet events were present. Change point and statistical analyses were applied to the longitudes to identify quantifiable changes, to allow detection of cross-scale linkages between drivers, and presence of feedback cycles. Agricultural was identified as the driver signal. Change points for agricultural expansion defined four distinct periods: 1852--1923, 1924--1948, 1949--1978 and 1979

  8. Broadening Participation in the Society for Integrative and Comparative Biology.

    Science.gov (United States)

    Wilga, Cheryl A D; Nishiguchi, Michele; Tsukimura, Brian

    2017-07-01

    The goal of the Society for Integrative and Comparative Biology's Broadening Participation Committee (SICB BPC) is to increase the number of underrepresented group (URG) members within the society and to expand their capabilities as future researchers and leaders within SICB. Our short-term 10-year goal was to increase the recruitment and retention of URG members in the society by 10%. Our long-term 25-year goal is to increase the membership of URG in the society through recruitment and retention until the membership demographic mirrors that of the US Census. Our plans to accomplish this included establishment of a formal standing committee, establishment of a moderate budget to support BPC activities, hosting professional development workshops, hosting diversity and mentor socials, and obtaining grant funds to supplement our budget. This paper documents broadening participation activities in the society, discusses the effectiveness of these activities, and evaluates BPC goals after 5 years of targeted funded activities. Over the past 5 years, the number of URG members rose by 5.2% to a total of 16.2%, members who report ethnicity and gender increased by 25.2% and 18%, respectively, and the number of members attending BPC activities has increased to 33% by 2016. SICB has made significant advances in broadening participation, not only through increased expenditures, but also with a commitment by its members and leadership to increase diversity. Most members realize that increasing diversity will both improve the Society's ability to develop different approaches to tackling problems within integrative biology, and help solve larger global issues that are evident throughout science and technology fields. In addition, having URG members as part of the executive committee would provide other URG members role models within the society, as well as have a voice in the leadership that represents diversity and inclusion for all scientists. © The Author 2017. Published by

  9. Provision of Effectiveness of University Education on the Market Economy

    Science.gov (United States)

    Kuznetsov, Nikolai; Usenko, Lyudmila; Ivanova, Olga; Kostoglodova, Elena

    2017-01-01

    Purpose: The purpose of this paper is to evaluate and determine the effectiveness of university education on the economy of various countries. Design/methodology/approach: To determine the necessity and expedience of making provision for the effectiveness of university education on the market economy, this work uses the method of regression and…

  10. 12 CFR 709.4 - Powers and duties of liquidating agent.

    Science.gov (United States)

    2010-01-01

    ... liquidating agent discovers the name of a creditor whose name does not appear on the credit union's books, a... discovery of the name and address. (c) General. The liquidating agent shall collect all obligations and... desirable or expedient in its discretion to wind up the affairs of the credit union including, but not...

  11. 40 CFR 144.70 - Wording of the instruments.

    Science.gov (United States)

    2010-07-01

    ...: Section 1. Definitions. As used in this Agreement: (a) The term “Grantor” means the owner or operator who... application of the purchase money or to inquire into the validity or expediency of any such sale or other... all injection wells covered must total the face amount shown below).] Face Amount: Policy Number...

  12. Использование продукции Autodesk и Dynamo в тоннелестроении

    OpenAIRE

    Мусиенко, Ю. А.

    2017-01-01

    In this article the speech about expediency of application of BIM of modeling will go to tunneling. We will review a concrete example of modeling of a tunnel with application of a linking of Revit and Dynamo. I will tell you about benefits on economic indicators and you will be pleasantly surprised.

  13. JPRS Report, Soviet Union, Kommunist, No. 14, September 1987.

    Science.gov (United States)

    1988-01-06

    archaeology , ethnography, and others. During his lifetime Vavilov collected with his expedi- tions a truly unique wealth: 160,000 live samples of... Maya 1987 Goda. Dokumenty i Materialy" [Visit to the Soviet Union by Vietnamese Communist Party 9. Vityuk, V.V and Efirov, S.A. "’Levyy’ Terrorizm na

  14. China Report, Economic Affairs, No. 369

    Science.gov (United States)

    1983-08-03

    Transportation Capacity Urged (SHIJIE JINGJI DAOBAO, 9 May 83) .. h2 Briefs Shandong Containerized Traffic ^ GENERAL Function of 󈧎-Year Patent" During...forum on economic work attended by responsible comrades of all prefectures and cities, Vice Governor Zhu Kui put forward five views on the question...TRANSPORTATION GREAT INCREASE IN TRANSPORTATION CAPACITY URGED Shanghai SHIJIE JINGJI DAOBAO in Chinese 9 May 83 P 1 [Article: "Disseminate Widely Used New

  15. La Riabilitazione del pavimento pelvico nella patologia uroginecologica

    OpenAIRE

    Demurtas, Pietro

    2009-01-01

    Pelvic floor muscle training is the most commonly recommended physical therapy treatment for women with urogynecological disorders. Pelvic floor muscle training is commonly recommended during pregnancy and after birth both for prevention and treatment of incontinence. OBJECTIVES: To determine the effects of pelvic floor muscle training for women with diagnoses of stress, urge and mixed incontinence. MATERIALS AND METHOD: 35 women with urodynamic diagnoses of stress, urge or mixed incon...

  16. These Days, Colleges Urge Young Alumni to Give... Posthumously

    Science.gov (United States)

    Love, Julia

    2012-01-01

    For college fund raisers, one bright spot in the economic doldrums is that it is easier to talk with potential donors about their deaths. As donors worry about outliving their assets, fund raisers find success--and often bigger donations--in asking them for bequests. Many college fund raisers have raised the subject of bequests more actively with…

  17. INTO CLEANNESS LEAPING : THE VERTIGINOUS URGE TO COMMIT HISTORY

    NARCIS (Netherlands)

    Runia, E.H.

    Surely one of the key issues in historiography is how to account for those mind-boggling and sometimes extremely bloody events in which we enter something really, sublimely new. In this essay my point of departure is that retrospectively it is almost impossible even for the historical actors

  18. Researchers urge climate-resilience support for South African maize ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    20 avr. 2016 ... Maize yields in parts of South Africa could decline by up to 20% by the 2050s as a result of climate change, research has shown. This could have a dramatic impact on subsistence farmers, with the poorest likely to be hardest hit. South Africa's Financial and Fiscal Commission tabled the findings for ...

  19. Foreign Minister urges EU unity on Russia / Matt Withers

    Index Scriptorium Estoniae

    Withers, Matt

    2008-01-01

    Välisminister Urmas Paet rõhutas Euroopa Liidu Üldasjade ja Välissuhete Nõukogu liikmete kohtumisel, et Euroopa Liit peab enne EL-i ja Venemaa vahelist tippkohtumist kujundama ühise arvamuse Venemaa-Gruusia konflikti suhtes

  20. Peer pressure, psychological distress and the urge to smoke.

    Science.gov (United States)

    Tsai, Yi-Wen; Wen, Yu-Wen; Tsai, Chia-Rung; Tsai, Tzu-I

    2009-06-01

    Psychology and addiction research have found that cigarette smokers react with subjective and automatic responses to stimuli associated with smoking. This study examines the association between the number of cigarettes smokers consume per month and their response to cues derived from peer and psychological distress. We studied 1,220 adult past and current smokers drawn from a national face-to-face interview survey administered in 2004. We defined two types of cues possibly triggering a smoker to have a cigarette: peer cues and psychological cues. We used ordinary least square linear regressions to analyze smoking amount and response to peer and psychological distress cues. We found a positive association between amount smoked and cue response: peer cues (1.06, 95%CI: 0.74-1.38) and psychological cues (0.44, 95%CI = 0.17-0.70). Response to psychological cues was lower among male smokers (-1.62, 95%CI = -2.26-(-)0.98), but response to psychological cues were higher among those who had senior high school level education (0.96, 95%CI = 0.40-1.53) and who began smoking as a response to their moods (1.25, 95%CI = 0.68-1.82). These results suggest that both peer cues and psychological cues increase the possibility of contingent smoking, and should, therefore, be addressed by anti-smoking policies and anti-smoking programs. More specifically, special attention can be paid to help smokers avoid or counter social pressure to smoke and to help smokers resist the use of cigarettes to relieve distress.

  1. Ilves urges closer ties while in Austria / Ella Karapetyan

    Index Scriptorium Estoniae

    Karapetyan, Ella

    2010-01-01

    President Toomas Hendrik Ilvese ametlik visiit Austria Vabariiki 22.11.2010 - 24.11.2010. Eesti riigipea pidas kõne Austria Majanduskojas Eesti-Austria majandusfoorumil, kohtus Alam-Austria Liidumaa parlamendi presidendi Hanz Penz'i ning Austria presidendi Heinz Fischeriga. Presidentide kohtumisel räägiti EL-i laienemispoliitikast, energiajulgeoleku probleemidest, Euroopa naabruspoliitikast ja idapartnerlusest

  2. Tourette Syndrome and Consciousness of Action

    Directory of Open Access Journals (Sweden)

    Andrea E. Cavanna

    2013-09-01

    Full Text Available Background: Tourette syndrome (TS is a neuropsychiatric disorder characterized by the chronic presence of multiple motor tics and at least one vocal/phonic tic since childhood. Tics typically change and vary in both intensity and severity over time, with remission and exacerbation common. In the vast majority of patients, tic expression is characteristically accompanied by discomforting bodily sensations, known as sensory phenomena or premonitory urges.Methods: We reviewed the existing literature on premonitory urges associated with the sense of voluntariness of action in TS.Results: Although the wish to move is perceived by the patient as involuntary, the decision to release the tic is often perceived by the patient as a voluntary capitulation to the subjective urge. Most patients with TS can exert a degree of control over the urge and constantly try to inhibit the movement. Based on these features, it has been suggested that tics performed in response to an urge to move should be classified as ‘unvoluntary’, as opposed to voluntary or involuntary acts. However, recent experimental data suggest that the brain areas involved in the generation of the wish to act show considerable overlap between healthy subjects and patients with TS.Discussion: The simultaneous presence of both voluntary and involuntary aspects in the expression of tic symptoms by patients with TS is consistent with the hypothesis that tics can have the same neurophysiologic substrate as voluntary acts, even though they are misperceived as being involuntary. This reinforces the view of TS as a hyperkinetic movement disorder primarily affecting the conscious experience of action.

  3. Preliminary standard review guide for Environmental Restoration/Decontamination and Decommissioning safety analyses

    International Nuclear Information System (INIS)

    Ellingson, D.R.

    1993-06-01

    The review guide is based on the shared experiences, approaches, and philosophies of the Environmental Restoration/Decontamination and Decommissioning (ER/D ampersand D) subgroup members. It is presented in the form of a review guide to maximize the benefit to both the safety analyses practitioner and reviewer. The guide focuses on those challenges that tend to be unique to ER/D ampersand D cleanup activities. Some of these experiences, approaches, and philosophies may find application or be beneficial to a broader spectrum of activities such as terminal cleanout or even new operations. Challenges unique to ER/D ampersand D activities include (1) consent agreements requiring activity startup on designated dates; (2) the increased uncertainty of specific hazards; and (3) the highly variable activities covered under the broad category of ER/D ampersand D. These unique challenges are in addition to the challenges encountered in all activities; e.g., new and changing requirements and multiple interpretations. The experiences in approaches, methods, and solutions to the challenges are documented from the practitioner and reviewer's perspective, thereby providing the viewpoints on why a direction was taken and the concerns expressed. Site cleanup consent agreements with predetermined dates for restoration activity startup add the dimension of imposed punitive actions for failure to meet the date. Approval of the safety analysis is a prerequisite to startup. Actions that increase expediency are (1) assuring activity safety; (2) documenting that assurance; and (3) acquiring the necessary approvals. These actions increase the timeliness of startup and decrease the potential for punitive action. Improvement in expediency has been achieved by using safety analysis techniques to provide input to the line management decision process rather than as a review of line management decisions. Expediency is also improved by sharing the safety input and resultant decisions with

  4. A Pharmaco-Economic Analyzis of Treating Severe Uncontrolled Child Asthma with Omalizumab — Actual Russian Clinical Practice Data

    Directory of Open Access Journals (Sweden)

    A. S. Kolbin

    2016-01-01

    Full Text Available Background: Omalizumab is the first and yet the only biopreparation for asthma which combines high efficiency and high cost. The clinical-economic expediency of using omalizumab in asthmatic children has not been previously studied in Russia.Objective: Our aim was to evaluate the clinical and economic expediency of using omalizumab as additive treatment (to basic or supporting therapy in children with severe uncontrolled atopic asthma under the Russian economic conditions.Methods: We conducted a mathematical simulation of asthma treatment in children with an increased frequency of hospitalization (9 times per year with an average monthly omalizumab requirement of 558 mg. The model is based on the Markov chain. The model includes direct and non-direct costs. The planning horizons were 2 and 5 years. We analyzed the efficiency and utility of the costs and their influence on the budget. The stability of received data is proven by sensitivity analyzis.Results: Over a 5-year planning horizon the cost of an additional year of quality life (due to using omalizumab was 1,259,185 roubles, while the “society’s solvency” is 1 341 308 roubles (cost utility analizis. It takes 39,820 rubles to prevent one hospitalization with omalizumab over a 5-year planning horizon (cost efficiency analizis, which is comparable to the cost of hospitalization (43,141 rubles. Total costs for treating 100 children with asthma, 7 of which would be treated with omalizumab, were equal to the amount of money which is enough to treat 105 children without omalizumab (analysis of budgetary influence.Conclusion: The analyses of cost efficiency and utility have shown that the strategy of using omalizumab together with standard treatment is economically expedient. Budgetary influence analysis has not detected a significant burden on the budget.

  5. PARALLEL IMPORT: REALITY FOR RUSSIA

    Directory of Open Access Journals (Sweden)

    Т. А. Сухопарова

    2014-01-01

    Full Text Available Problem of parallel import is urgent question at now. Parallel import legalization in Russia is expedient. Such statement based on opposite experts opinion analysis. At the same time it’s necessary to negative consequences consider of this decision and to apply remedies to its minimization.Purchase on Elibrary.ru > Buy now

  6. Factors contributing to morbidity and mortality among preterm ...

    African Journals Online (AJOL)

    Objective: Prematurity is one of the highest global health challenges of the 21st century and has been named the first killer of young children. In Rwanda, it is the leading cause of death in neonates. It is expedient to explore the factors contributing to the observed high morbidity and mortality to plan appropriate interventions.

  7. Nuclear power in an age of reason

    International Nuclear Information System (INIS)

    Fells, I.

    1980-01-01

    An overview is given of many questions raised by the use of nuclear power. Problems considered include; energy demands and policies, economics, political expediency, the anti-nuclear lobby, problems of communication, confrontation between workers and management, training of reactor personnel, education of the public, and methods of improving the credibility of the industry. (U.K.)

  8. The neural basis of the imitation drive.

    Science.gov (United States)

    Hanawa, Sugiko; Sugiura, Motoaki; Nozawa, Takayuki; Kotozaki, Yuka; Yomogida, Yukihito; Ihara, Mizuki; Akimoto, Yoritaka; Thyreau, Benjamin; Izumi, Shinichi; Kawashima, Ryuta

    2016-01-01

    Spontaneous imitation is assumed to underlie the acquisition of important skills by infants, including language and social interaction. In this study, functional magnetic resonance imaging (fMRI) was used to examine the neural basis of 'spontaneously' driven imitation, which has not yet been fully investigated. Healthy participants were presented with movie clips of meaningless bimanual actions and instructed to observe and imitate them during an fMRI scan. The participants were subsequently shown the movie clips again and asked to evaluate the strength of their 'urge to imitate' (Urge) for each action. We searched for cortical areas where the degree of activation positively correlated with Urge scores; significant positive correlations were observed in the right supplementary motor area (SMA) and bilateral midcingulate cortex (MCC) under the imitation condition. These areas were not explained by explicit reasons for imitation or the kinematic characteristics of the actions. Previous studies performed in monkeys and humans have implicated the SMA and MCC/caudal cingulate zone in voluntary actions. This study also confirmed the functional connectivity between Urge and imitation performance using a psychophysiological interaction analysis. Thus, our findings reveal the critical neural components that underlie spontaneous imitation and provide possible reasons why infants imitate spontaneously. © The Author (2015). Published by Oxford University Press.

  9. Responsivity to food cues in bulimic women and controls.

    Science.gov (United States)

    Staiger, P; Dawe, S; McCarthy, R

    2000-08-01

    The current study investigated responsivity to individualized food cues consisting of binge/favourite foods in 17 women with bulimic nervosa (BN) and 17 women with no history or current symptoms of eating disorders (C). The hypothesis that increasing cue salience would be associated with an increase in responsivity was tested by comparison of self reported urges, affective responses and salivation to the sight and smell (SS) and the sight, smell and taste (SST) of a binge/favourite food compared to a neutral stimulus (lettuce leaf). As predicted, the BN group reported a greater urge to binge and higher levels of stress/arousal to selected binge/favourite food cues compared to the C group. The BN group also reported lower confidence to resist the urge to binge and control over food intake compared to the C group. Further, a series of planned comparisons in the BN group found that the urge to binge, stress, and loss of control were greater when participants were exposed to the SST cue than to the SS cue. There was no difference between the groups in salivary responsivity to food cues. These results are discussed in terms of a conditioning model of cue reactivity. Copyright 2000 Academic Press.

  10. Cystitis as a correlate of female urinary incontinence

    DEFF Research Database (Denmark)

    Mommsen, S.; Foldspang, Anders; Elving, Lisbeth Bach

    1994-01-01

    of episodes of cystitis and UI related to cystitis in adult life, and prevalence of relative risks, as indicated by odds ratio (OR), of UI conditional on cystitis experience. Results indicated that the 1987 period prevalences of UI provoked by physical stress and UI associated with a feeling of urge were 15......-reported data based on postal questionnaires. The sample consisted of 3114 women, out of whom 2613 (84%) delivered the information requested. The main outcome measures were period prevalence in 1987 of episodes of UI provoked by physical stress and UI associated with a feeling of urge, prevalence of experience......% and 9%, respectively. Forty-five per cent reported a history of cystitis and 10% of UI during episodes of cystitis. Both UI provoked by stress and UI associated with a feeling of urge were significantly correlated to cystitis (OR 2.1, P

  11. Role of the ecological audit in information support of the domestic market of eco-textile

    Directory of Open Access Journals (Sweden)

    Semak Bohdan B.

    2014-01-01

    Full Text Available The goal of the article is the study of the place and role of the ecological audit in the system of ecological management of textile enterprises of Ukraine, ecologisation of technologies of textile manufacture, formation of the range and quality and ensuring ecological safety of products of textile enterprises. In the result of the study the article specifies the role and place of the ecological audit in formation of the system of ecological management of enterprises of the domestic textile industry. Special attention is paid to the role of the ecological audit in information support to participants of the domestic eco-textile market. The article justifies expediency of the use of results of ecological audit of textile products with the aim of increasing its competitiveness in the market. It is expedient to conduct further studies in the directions of development of mechanisms of introduction of the ecological audit at textile enterprises of Ukraine and study of influence of ecological audit of products of domestic textile enterprises upon satisfaction of growing ecological needs of consumers of these products in Ukraine.

  12. Model study of an automatic controller of the IBR-2 pulsed reactor

    International Nuclear Information System (INIS)

    Pepelyshev, Yu.N.; Popov, A.K.

    2007-01-01

    For calculation of power transients in the IBR-2 reactor a special mathematical model of dynamics taking into account the discontinuous jump of reactivity by an automatic controller with the step motor is created. In the model the nonlinear dependence of the energy of power pulse on the reactivity and the influence of warming up of the reactor on the reactivity by means of introduction of a nonlinear feedback 'power-pulse energy - reactivity' are taken into account. With the help of the model the transients of relative deviation of power-pulse energy are calculated at various (random, mixed and regular) reactivity disturbances at the reactor mean power 1.475 MW. It is shown that to improve the quality of processes the choice of such regular values of parameters of the automatic controller is expedient, at which the least effect of smoothing of a signal acting on an automatic controller and the least speed of an automatic controller are provided, and the reduction of efficiency of one step of the automatic controller and introduction of a five-percent dead space are also expedient

  13. Computerizing clinical practice guidelines

    DEFF Research Database (Denmark)

    Lyng, Karen Marie

    It is well described that hospitals have problems with sustaining high quality of care and expedient introduction of new medical knowledge. Clinical practice guidelines (CPGs) have been promoted as a remedy to deal with these problems. It is, however, also well described that application and comp......It is well described that hospitals have problems with sustaining high quality of care and expedient introduction of new medical knowledge. Clinical practice guidelines (CPGs) have been promoted as a remedy to deal with these problems. It is, however, also well described that application...... is comprised by fieldwork in three oncology departments and a case study of advanced life support. Although close to all patients within oncology are treated according to a CPG, I found limited application of physical CPGs and web-based CPG portals. However, I found comprehensive application of activity...... of the business strategic aims, and 3) analysis and formalization of CPGs. This will imply orchestration of design teams with competencies from a wide array of disciplines such as health practice, business management, knowledge management and information systems....

  14. Integrated doses calculation in evacuation scenarios of the neutron generator facility at Missouri S&T

    Energy Technology Data Exchange (ETDEWEB)

    Sharma, Manish K.; Alajo, Ayodeji B., E-mail: alajoa@mst.edu

    2016-08-11

    Any source of ionizing radiations could lead to considerable dose acquisition to individuals in a nuclear facility. Evacuation may be required when elevated levels of radiation is detected within a facility. In this situation, individuals are more likely to take the closest exit. This may not be the most expedient decision as it may lead to higher dose acquisition. The strategy followed in preventing large dose acquisitions should be predicated on the path that offers least dose acquisition. In this work, the neutron generator facility at Missouri University of Science and Technology was analyzed. The Monte Carlo N-Particle (MCNP) radiation transport code was used to model the entire floor of the generator's building. The simulated dose rates in the hallways were used to estimate the integrated doses for different paths leading to exits. It was shown that shortest path did not always lead to minimum dose acquisition and the approach was successful in predicting the expedient path as opposed to the approach of taking the nearest exit.

  15. Neural correlates of moral judgment in pedophilia

    OpenAIRE

    Massau, Claudia; Kärgel, Christian; Weiß, Simone; Walter, Martin; Ponseti, Jorge; HC Krueger, Tillmann; Walter, Henrik; Schiffer, Boris

    2017-01-01

    Abstract Pedophilia is a sexual preference that is often associated with child sex offending (CSO). Sexual urges towards prepubescent children and specifically acting upon those urges are universally regarded as immoral. However, up until now, it is completely unknown whether moral processing of sexual offenses is altered in pedophiles. A total of 31 pedophilic men and 19 healthy controls were assessed by using functional magnetic resonance imaging (fMRI) in combination with a moral judgment ...

  16. Condutas de enfermagem diante das vítimas de ferimentos por armas de fogo em serviço de atendimento móvel de urgência

    Directory of Open Access Journals (Sweden)

    Jobson Henrique Silveira Alves

    2016-10-01

    Full Text Available O atendimento pré-hospitalar é fundamental para pacientes vítimas de ferimento por arma de fogo, pois é essencial na redução das sequelas decorrentes da mesma, assim como para melhores condições de sobrevida das vítimas. As lesões provenientes por disparos de arma de fogo são uma das mais incidentes formas de violência atualmente, representando um problema de saúde pública pela frequência com que ocorre; devido a fatores como este, vê-se a importância da assistência de enfermagem qualificada ainda na cena da ocorrência. O estudo objetiva descrever as condutas do enfermeiro atuante no Serviço de Atendimento Móvel de Urgência (SAMU frente às ocorrências com vítimas Ferimentos por Armas de Fogo (FAF. O estudo é do tipo descritivo, exploratório, com abordagem quantiqualitativa, com participação de nove enfermeiras mediante assinatura do Termo de Consentimento Livre e Esclarecido, através de um questionário contendo perguntas objetivas e subjetivas. Os resultados mostram 56% dos entrevistados revelam não enfrentar dificuldades na assistência as vítimas de FAF, porém os relatados foram em relação a segurança da equipe e a falta de auxílio para conter os cidadãos que acompanham o atendimento com curiosidade; 100% da amostra participaram de cursos de treinamento. Em relato todas as enfermeiras entrevistadas já prestaram conduta a vítima de FAF e a consideram a assistência de enfermagem prestada no atendimento pré-hospitalar (APH como resolutiva. Nursing conducts front of victims injured by firearms in emergency mobile care serviceAbstract: The prehospital care is critical to patient injury victims by firearms, it is essential to reduce the consequences resulting from it, as well as better conditions of survival of the victims. Injuries from firearm shots are one of the incidents forms of violence currently representing a public health problem by the frequency with which it occurs; due to factors like this, we

  17. Synthesis of 2-(oxadiazolo, pyrimido, imidazolo, and benzimidazolo ...

    Indian Academy of Sciences (India)

    Abstract. Exceedingly facile single-step expedient protocols based on the versatility and reactivity of corre- ..... a solid to a solution of compound 12 (0.0015 mol) in. DMSO (1mL) and ... Following extraction with EtOAc (15 mL), the organic phase was ... the literature as the most active pharmacophores in drug design and ...

  18. [Application of magnetic therapy in acute paraproctitis].

    Science.gov (United States)

    Kondratenko, P G; Elin, F E; Avraimov, S L; Sobolev, D V

    2003-09-01

    There were studied the possibilities and perspectives of application of the magnetically liquefied layer as an instrument for better purulent and putrefactive wounds clearance after intervention for an acute paraproctitis. Together with clinical signs the results of bacteriological investigation were controlled as well. There was established high efficacy of the method proposed and expedience of its application.

  19. Social Media Integration into State-Operated Fusion Centers and Local Law Enforcement: Potential Uses and Challenges

    Science.gov (United States)

    2010-12-01

    NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS Approved for public release; distribution is unlimited SOCIAL MEDIA...DATE December 2010 3. REPORT TYPE AND DATES COVERED Master’s Thesis 4. TITLE AND SUBTITLE Social Media Integration into State-Operated Fusion...technologies, particularly social media, within fusion centers and local law enforcement entities could enable a more expedient exchange of information among

  20. Use of abundance of one species as a surrogate for abundance of others

    Science.gov (United States)

    Samuel A. Cushman; Kevin S. McKelvey; Barry R. Noon; Kevin McGarigal

    2010-01-01

    Indicator species concepts have a long history in conservation biology. Arguments in favor of these approaches generally stress expediency and assume efficacy. We tested the premise that the abundance patterns of one species can be used to infer those of other species. Our data consisted of 72,495 bird observations on 55 species across 1046 plots distributed across 30...

  1. Efficiency Evaluation of Construction of Steam-Turbine Power Plants at Industrial Enterprises

    Directory of Open Access Journals (Sweden)

    A. L. Starzhinsky

    2007-01-01

    Full Text Available It is shown that application of own power stations at an industrial enterprise is considered as an expedient one if there is an availability of thermal power sources because value of an optimization criterion exceeds corresponding optimization criterion by 2.1-4.6 fold when an enterprise is supplied with power only from power system networks.

  2. Architecture and prototype of human-machine interface with mobile robotic device

    International Nuclear Information System (INIS)

    Dyumin, A.A.; Sorokoumov, P.S.; Chepin, E.V.; Urvanov, G.A.

    2013-01-01

    The possibility of controlling mobile robotic (MRD) device is analyzed and a prototype control system is described. It is established that, for controlling MRD, it is expedient to use a brain-computer interface. A system of interpretation of information obtained from the operator brain has been developed and used in the proposed prototype control system [ru

  3. Dewatering a gasification zone in the Dnieper region for underground coal gasification

    Energy Technology Data Exchange (ETDEWEB)

    Sedenko, M V

    1957-01-01

    The processes for draining brown coal open-pit mines are described. Experience with water inflow in open-pit mines of the Dnieper region and stratigraphic cross section and hydrogeological conditions in the area of the planned gasification installation are discussed. Expedient draining by boreholes is described, and arrangement of boreholes and filters is shown. Cost data are presented.

  4. Neuroprotective action of magneto-lasertherapy during the acute period of ischemic insult

    International Nuclear Information System (INIS)

    Samosyuk, N.I.; Ehkshi Il'ker

    2001-01-01

    New methods of ischemic insult treatment, in particular use of magneto-lasertherapy are described. Patients with different forms of ischemic insult were treated during acute period of it. Restoration of functions was registered in 80% of them. Clinical studies show considerable morphoprotective effect of this method and the expediency of its introduction in intensive ischemic insult therapy

  5. Educational topics for school from the perspective of professionals in the Mobile Emergency Service.

    Science.gov (United States)

    Mota, Larissa Larie; Andrade, Selma Regina de

    2016-06-01

    To systematize, with professionals from the Mobile Emergency Care Service of Santa Catarina municipality, the main issues for the development of an educational tool of attention to the emergency room, dedicated to the school-age population. Qualitative study, conducted through meetings in the focus group format, with 19 professionals who develop their activities in the city Emergency Mobile Emergency Service. Data were categorized and analyzed using thematic analysis technique. The contents discussed at the meetings were grouped into four thematic categories: The Mobile Emergency Service and the school: education and health promotion for children; As the Mobile Emergency Care Service works: What is important to know ?; Something's wrong, what now? and; We are nearly finished, give your opinion. The specific issues arising from the meetings contributed to the production of an educational tool on the activities of the Mobile Emergency Service, which may be used by the School Health Program to promote health education in the care area to the emergency room with the population schoolchildren. Sistematizar, junto aos profissionais do Serviço de Atendimento Móvel de Urgência de um município catarinense, os principais temas para a elaboração de um instrumento educativo sobre atenção às urgências, dedicado à população em idade escolar. Estudo qualitativo, realizado por meio de encontros no formato de grupo focal, com 19 profissionais que desenvolvem suas atividades no Serviço de Atendimento Móvel de Urgência municipal. Os dados foram categorizados e analisados com a técnica de análise temática. Os conteúdos debatidos nos encontros foram agrupados em quatro categorias temáticas: O Serviço de Atendimento Móvel de Urgência e a escola: educação e promoção da saúde para as crianças; Como o Serviço de Atendimento Móvel de Urgência funciona: o que é importante saber?; Tem algo errado, e agora? e; Estamos quase concluindo, dê sua opinião. Os

  6. Managing an evolution: Deregulation of the electric utility industry

    Energy Technology Data Exchange (ETDEWEB)

    Skinner, S.K.

    1994-12-31

    The author discusses the emerging competitive situation in the electric power industry as deregulation of electric utilities looms on the horizon. The paper supports this change, and the competition it will bring, but urges caution as changes are instituted, and the regulatory bodies decide how and how much to free, and at what rates. The reason for his urge for caution comes from historical experience of other industries, which were smaller and had less direct impact on every American.

  7. Engine restart aid

    Science.gov (United States)

    Fedewa, Andrew

    2018-01-09

    A system is disclosed comprising an engine having coolant passages defined therethrough, a first coolant pump, and a first radiator. The system additionally comprises a second coolant pump, a second radiator, and a liquid-to-air heat exchanger configured to condition the temperature of intake air to the engine. The system further includes a coolant valve means. For a first configuration of the coolant valve means the first coolant pump is configured to urge coolant through the coolant passages in the engine and through the first radiator, and the second coolant pump is configured to urge coolant through the liquid-to-air heat exchanger and through the second radiator. For a second configuration of the coolant valve means the second coolant pump is configured to urge coolant through the coolant passages in the engine and through the liquid-to-air heat exchanger. A method for controlling the system is also disclosed.

  8. Post-stroke urinary incontinence with impaired awareness of the need to void: clinical and urodynamic features.

    Science.gov (United States)

    Pettersen, Renate; Stien, Ragnar; Wyller, Torgeir B

    2007-05-01

    To describe a clinical subtype of urinary incontinence (UI) after a stroke, i.e. with impaired awareness of the need to void (IA-UI), and to compare it to urge UI after a stroke for the risk factors and medium-term outcome. In a consecutive sample of 315 hospitalized stroke patients who were clinically stable and able to communicate, 65 with UI were identified (27 urge UI, 38 IA-UI). All had a comprehensive clinical assessment and cerebral computed tomography (CT). Cysto-urethrometry was performed in seven patients with IA-UI. Of the 38 patients with IA-UI, 16 were partially aware of leakage, but not of bladder fullness; the remaining 22 denied leakage. Patients with IA-UI were more functionally impaired (P=0.001), had more visible new CT lesions (24 of 38 vs 10 of 27, P=0.04) and less frontal lobe involvement (seven of 24 vs seven of 10, P=0.05) than those with urge UI. Ten of 12 patients with parietal lobe involvement denied leakage; no particular lesion pattern was found in those with partial awareness. Two patients had normal cysto-urethrometry, four showed terminal detrusor overactivity, and one had an incompetent urethral closure mechanism. In all, bladder sensation was reduced or absent. Only two of the surviving patients had regained continence after 1 year, whereas half of those with urge UI had become continent. IA-UI after a stroke differs from urge UI in clinical and prognostic respects, and probably reflects greater brain damage. It might explain the prognostic importance of stroke-related UI. There are various urodynamic patterns. Patients with better preserved insight might benefit from early awareness training and even from additional medical treatment if bladder overactivity is present; this needs further investigation.

  9. Does gender moderate the subjective measurement and structural paths in behavioural and cognitive aspects of gambling disorder in treatment-seeking adults?

    Science.gov (United States)

    Smith, David; Battersby, Malcolm; Harvey, Peter

    2015-09-01

    Gender differences have been observed in the pathogenesis of gambling disorder and gambling related urge and cognitions are predictive of relapse to problem gambling. A better understanding of these mechanisms concurrently may help in the development of more directed therapies. We evaluated gender effects on behavioural and cognitive paths to gambling disorder from self-report data. Participants (N=454) were treatment-seeking problem gamblers on first presentation to a gambling therapy service between January 2012 and December 2014. We firstly investigated if aspects of gambling related urge, cognitions (interpretive bias and gambling expectancies) and gambling severity were more central to men than women. Subsequently, a full structural equation model tested if gender moderated behavioural and cognitive paths to gambling severity. Men (n=280, mean age=37.4years, SD=11.4) were significantly younger than women (n=174, mean age=48.7years, SD=12.9) (pgambling severity, gambling related urge, interpretive bias and gambling expectancies. The paths for urge to gambling severity and interpretive bias to gambling severity were stronger for men than women and statistically significant (pgambling expectancies to gambling severity were insignificant for both men and women. This study detected an important signal in terms of theoretical mechanisms to explaining gambling disorder and gender differences. It has implications for treatment development including relapse prevention. Copyright © 2014 Elsevier Ltd. All rights reserved.

  10. Hard Times, Expedient Measures: Women Teachers in Queensland Rural Schools, 1920-50.

    Science.gov (United States)

    Meadmore, Peter

    1999-01-01

    Examines women teachers who taught in one-teacher schools in Queensland, Australia, from 1920-50. Discusses the research and provides a historical context. Focuses on topics such as teaching as a career, women teachers and marriage, unequal pay, and living conditions of women teachers. (CMK)

  11. [Helping as a matter of expedience? Ethical objections against prioritization in medicine].

    Science.gov (United States)

    Maio, G

    2012-04-01

    The paper discusses the question whether it could be ethically appropriate to "resolve" the problem of scarce resources in health care via priority lists. It is argued that such a schematical priority list could only be undisputed in ethical respects if it represented a broad consensus on the question what a good life would be. Priority lists are always implicit decisions about specific concepts of the good life. Using a priority list only in consideration of a mere cost-benefit ratio means to accept a mere utilitarian way of defining good life. Such a definition goes with neglect of the interests of people with chronic diseases, of patients with incurable diseases, of patients with a limited life expectancy. To neglect the interests of these patients means to abandon the core of medical identity, because medicine has the mission to help those above all who are most in need and those who cannot help themselves. And so we have to realize that for medicine there are some values which are more important than economic considerations. The physician is a person who gives a promise, the promise to be there for the patient. If the physician now is becoming a businessman, this promise is no longer valid. The businessman doesn't give any other promise than not to act against the contract. But the main need of the patient, his longing for a human person whom he can trust, cannot become part of a contract. Especially in our time medicine has to fight for the core of its identity. © Georg Thieme Verlag KG Stuttgart · New York.

  12. Arms Control Verification: ’Bridge’ Theories and the Politics of Expediency.

    Science.gov (United States)

    1983-04-01

    follow that the two States define deterrence and detente differently as well. For the U.S., deterrence has long been the fundemental objective of...between 1970 and 1979 including ’military investment " (procurement, military construction, RDT&E) but excluding operating costs on both sides; The...Pentagon’s PY 1982 Posture Statement to Congress: $270 billion between 1968 and 1979 (by including 1968 and 1969 when American investment was slightly higher

  13. Environmental Restoration - Expedient Methods and Technologies: A User Guide with Case Studies

    Science.gov (United States)

    1998-03-01

    Tarradella, Joseph, Gabriel Bitton, and Dominique Rossel. Soil Ecotoxicology . Lewis Publishers, Boca Raton, Florida, 1997. Testa, Stephen M. The Reuse...to the first lift to adjust the nutrients in the soil. No nutrient adjustments were made to the second lift. Each lift was cultivated once or twice a...Technology Transfer Committee, Second Edition, October 1994. Tarradella, Joseph, Gabriel Bitton, and Dominique Rossel. Soil Ecotoxicology . Lewis

  14. Overview of naturally permeable fractured reservoirs in the central and southern Upper Rhine Graben: Insights from geothermal wells

    OpenAIRE

    Vidal , Jeanne; Genter , Albert

    2018-01-01

    International audience; Since the 1980′s, more than 15 geothermal wells have been drilled in the Upper Rhine Graben (URG), representing more than 60 km of drill length. Although some early concepts were related to purely matrix-porosity reservoirs or Hot Dry Rock systems, most projects in the URG are currently exploiting the geothermal resources that are trapped in fracture networks at the base of the sedimentary cover and in the granitic basement. Lessons-learnt from the European EGS referen...

  15. Flowering to bloom of PeV scale supersymmetric left–right ...

    Indian Academy of Sciences (India)

    foreseeable future, and hence deserve the name just beyond the Standard Model (JBSM)?. Left–right symmetric model [1,2] needs a supersymmetric extension as an expedient for avoiding the hierarchy problem. The minimal set of Higgs superfields required, with their SU(3) ⊗ SU(2)L ⊗ SU(2)R ⊗ U(1)B−L is, i = (1, 2, 2, 0),.

  16. Possible distortion of autoradiographic results

    Energy Technology Data Exchange (ETDEWEB)

    Kozlov, A.A.; Tumanushvili, G.D. (AN Gruzinskoj SSR, Tbilisi. Inst. Ehksperimental' noj Morfologii)

    1980-01-01

    The effect of radioactive labelling (H/sup 3/-thymidine) on the infusorian division is studied. The presented results show that introduction of labelled compounds results in accelerating infusorian cell division v. Thorough investigation of labelled compound effect with low activity on the parameters of cell division and the search of methods to eliminate distortions able to appear in autoradiographic experiments is expedient.

  17. The possible distortion of autoradiographic results

    International Nuclear Information System (INIS)

    Kozlov, A.A.; Tumanushvili, G.D.

    1980-01-01

    The effect of radioactive labelling (H 3 -thymidine) on the infusorian division is studied. The presented results show that introduction of labelled compounds results in accelerating infusorian cell division v. Thorough inestigation of labelled compound effect with low activity on the parameters of cell division and the search of methods to eliminate distortions able to appear in autoradiographic experiments is expedient [ru

  18. Aging in the United States: Opportunities and Challenges for Otolaryngology-Head and Neck Surgery.

    Science.gov (United States)

    Chiu, Brandon L; Pinto, Jayant M

    2018-05-17

    The number of Americans over the age of 65 has been growing much faster than the overall population's growth rate. These changes can be largely attributed to the improvement in life expectancy. This demographic shift yields a unique and exciting opportunity to provide both expedient and cost-efficient care to a growing patient population. Copyright © 2018 Elsevier Inc. All rights reserved.

  19. Body mass index and adult female urinary incontinence

    DEFF Research Database (Denmark)

    Mommsen, Søren; Foldspang, Anders

    1994-01-01

    rate of response was 85%, and the present analysis comprises 2,589 women who supplied information about their body weight and height. The period prevalence of all UI, stress UI, urge UI, and mixed stress and urge UI was 17%, 15%, 9%, and 7%, respectively. The mean body mass index (BMI) was 22.7 kg/m2......The aim of the present investigation was to study the possible role of obesity in the etiology of adult female urinary incontinence (UI). A random population sample of 3,114 women aged 30–59 years were mailed a questionnaire concerning UI and, among other things, body weight and height. The overall....... Irrespective of other risk indicators, BMI was positively associated with UI prevalence (OR, 1.07/BMI unit; Pstress UI prevalence, with cystitis in predicting urge UI, and with both in predicting mixed UI. Stress UI proved to be the UI type most closely...

  20. The establishment and analysis of TRACE model for ultimate response guideline of Chinshan nuclear power plant - 15448

    International Nuclear Information System (INIS)

    Huang, J.J.; Wang, J.R.; Shih, C.; Chen, S.W.; Liao, L.Y.; Lin, H.T.

    2015-01-01

    The purpose of this research is to use TRACE code to perform a simulation that executes the procedures of URG (Ultimate Response Guidelines) to deal with Fukushima-like accidents. TRACE is an advanced thermal hydraulic code that has been developed by the United States Nuclear Regulatory Commission for NPP safety analysis. In this work TRACE has been used to analyze the thermal hydraulic model for the URG of the Chinshan nuclear power plant that is composed of 2 BWR-type reactors. URG includes 2-stage depressurization, alternative water injection and removing decay heat through the ejection from containment. The 2-stage depressurization strategy includes controlled depressurization and emergency depressurization to replace traditional one-stage depressurization. Results show that by comparing with one-stage depressurization strategy, 2-stage depressurization strategy is able to reduce peak cladding temperature (PCT) effectively and needs much less minimum flow rate of alternative water injection in the accident

  1. Prevalence of burnout syndrome among nurses in urgency and emergency hospital system

    OpenAIRE

    Dantas, Tatiana Rodrigues da Silva; Carreiro, Bruno Oliveira; Pascoal, Francilene Figueirêdo da Silva; Moraes, Marina Nascimento de; Cordeiro, Renata Cavalcanti; Filha, Maria de Oliveira Ferreira

    2014-01-01

    Objetivo: investigar a prevalência de Burnout entre enfermeiros de hospitais de urgência e emergência no Estado da Paraíba. Método: trata-se de uma pesquisa descritiva, transversal, quantitativa realizada em seis hospitais especializados no atendimento às urgências e emergências no estado. A amostra foi constituída por 110 enfermeiros. Utilizou-se como instrumento o Maslach Burnout Inventory. Os dados foram analisados com o auxílio do SPSS-Statistical Package for the Social Sciences na versão...

  2. Caracterização das vítimas de ferimentos por arma de fogo, atendidas pelo Serviço de Atendimento Móvel de Urgência em Campo Grande-MS Characterization of victims injured by firearms assisted by the Mobile Emergency Care Service in Campo Grande-MS

    Directory of Open Access Journals (Sweden)

    Simone Sanches

    2009-03-01

    Full Text Available A violência, em todas as suas apresentações, tem crescido de forma avassaladora no país, elevando os indicadores de morbidade e mortalidade por causas externas. O uso das armas de fogo, muitas vezes, faz vítimas fatais ou que podem permanecer sequeladas. Tal fato tem aumentado o ônus do estado com internações hospitalares e acréscimo dos anos de vida perdidos da população jovem, que constitui a grande maioria dessas vítimas. Nesse sentido, o presente estudo objetivou fazer um levantamento das vítimas de ferimentos por arma de fogo, atendidas pelo Serviço de Atendimento Móvel de Urgência no município de Campo Grande-MS, no período de abril de 2005 a abril de 2007, nos dois primeiros anos de funcionamento, desde a implantação desse serviço na capital do Estado de Mato Grosso do Sul. Realizou-se estudo descritivo, baseado em análise documental do sistema de informação do SAMU do município de Campo Grande-MS. Foram descritos 233 atendimentos. Os resultados evidenciaram 213 vítimas do sexo masculino, a faixa etária mais acometida foi dos 20 aos 24 anos de idade, a cabeça e o pescoço foram as partes do corpo mais atingidas e a região Sul do município de Campo Grande foi a que concentrou maior número de atendimentos. Conclui-se que a violência por arma de fogo em Campo Grande-MS atinge a camada economicamente ativa da população e provém de regiões de bolsões de pobreza e desigualdade social, justificando a implantação de um serviço como o SAMU.Violence has grown in an overwhelming way in Brazil, raising the indicators of morbidity and mortality by external causes. Many times, the use of firearms makes fatal victims or victims who may remain disabled. This fact has increased the State's onus regarding hospital costs and also the number of life years that the young population loses, as it forms the majority of the victims. The present study aimed to survey the victims of injuries caused by firearms, assisted by

  3. Occupational stress of nurses in emergency care: an integrative review of the literature Estrés laboral de los enfermeros de urgencia y emergencia: revisión integradora de literatura Estresse ocupacional dos enfermeiros de urgência e emergência: Revisão Integrativa da Literatura

    Directory of Open Access Journals (Sweden)

    Francimar Nipo Bezerra

    2012-01-01

    competitividad y distanciamiento entre teoría y práctica. CONCLUSIÓN: El sentido del trabajo para los profesionales contribuye para su protección contra el sufrimiento y el estrés ocupacional.OBJETIVO: Analisar a produção científica relacionada ao modo como o estresse ocupacional está presente na vida do enfermeiro que atua no cenário da urgência e emergência. MÉTODOS: Foi realizada uma revisão integrativa da literatura nas bases de dados Bdenf, Lilacs, Medline, Pubmed e no repositório Scielo. Os critérios de inclusão para a seleção da amostra foram: artigos publicados em português e inglês que retratassem a temática em estudo, publicados e indexados nas referidas bases nos últimos 10 anos. RESULTADOS: Foram selecionados oito artigos. Os resultados apontaram que o estresse ocupacional dos enfermeiros de urgência e emergência está relacionado à escassez de recursos humanos e à carga horária de trabalho, instalações físicas e recursos materiais inadequados, além de plantões noturnos, interface trabalho-lar, relacionamentos interpessoais, trabalho em clima de competitividade e distanciamento entre teoria e prática. CONCLUSÃO: O sentido do trabalho para os profissionais contribui para sua proteção contra o sofrimento e o estresse ocupacional.

  4. NSAID-GASTRODUODENOPATHIES IN PATIENTS WITH OSTEOARTHRITIS: PECULIARITIES OF DIAGNOSTICS, PREVENTION AND TREATMENT

    Directory of Open Access Journals (Sweden)

    A. S. Svintzitzky

    2002-01-01

    Full Text Available Objective. To improve both prophylaxis and treatment of NSA ID-associated gastroduodenopathies in osteoar- thritic patients. Material and methods. The study included 155 osieoarthritic pts., NSAID-therapy included ibuprofen, meloxi- cam or different forms of diclofenac. Endoscopy before investigation, on the 4-5"' day and on the 3 ,J week (with gastrobiopsy in 37 was performed, as well as basal intragastric pH study (in 57, basal cortisolemia level - immunoassay (in 124. Diagnosis of Helicobacter pylori (in 88 by ELISA and biochemical methods. Results. Taking into account both NSAID-therapy duration and its methods used, the risk-factors presented, patients’ Helicobacter pylori-status and their adrenal glands’ cortisol-productive function, it has been described the frequency of the revealed erosive-and-ulcerous lesions, as well as their clinical and endoscopic peculiarities. The efficacy of ulcers monotherapy with misoprostol has been evaluated. Conclusion. It is expedient first local, then prostaglandin-dependent gastroprotection while taking NSAID, both in Hp-negative and positive pts. Concomitant Helicobacter pylori-infection does not worsen 3-week NSAID- therapy gastric tolerability, but hypercortisolemia does so. Misoprostol proved to be expedient in ulserous gas- troduodcnopathy .

  5. ASSESSING AND FORECASTING, BY PLAY, NATURAL GAS ULTIMATE RECOVERY GROWTH AND QUANTIFYING THE ROLE OF TECHNOLOGY ADVANCEMENTS IN THE TEXAS GULF COAST BASIN AND EAST TEXAS

    Energy Technology Data Exchange (ETDEWEB)

    William L. Fisher; Eugene M. Kim

    2000-12-01

    A detailed natural gas ultimate recovery growth (URG) analysis of the Texas Gulf Coast Basin and East Texas has been undertaken. The key to such analysis was determined to be the disaggregation of the resource base to the play level. A play is defined as a conceptual geologic unit having one or more reservoirs that can be genetically related on the basis of depositional origin of the reservoir, structural or trap style, source rocks and hydrocarbon generation, migration mechanism, seals for entrapment, and type of hydrocarbon produced. Plays are the geologically homogeneous subdivision of the universe of petroleum pools within a basin. Therefore, individual plays have unique geological features that can be used as a conceptual model that incorporates geologic processes and depositional environments to explain the distribution of petroleum. Play disaggregation revealed important URG trends for the major natural gas fields in the Texas Gulf Coast Basin and East Texas. Although significant growth and future potential were observed for the major fields, important URG trends were masked by total, aggregated analysis based on a broad geological province. When disaggregated by plays, significant growth and future potential were displayed for plays that were associated with relatively recently discovered fields, deeper reservoir depths, high structural complexities due to fault compartmentalization, reservoirs designated as tight gas/low-permeability, and high initial reservoir pressures. Continued technology applications and advancements are crucial in achieving URG potential in these plays.

  6. EXERCÍCIO DA LIDERANÇA DO ENFERMEIRO EM UM SERVIÇO DE URGÊNCIA E EMERGÊNCIA

    Directory of Open Access Journals (Sweden)

    Simone Coelho Amestoy

    2016-01-01

    Full Text Available Este estudo objetivou conhecer o exercício da liderança de enfermeiros que trabalham em um serviço de urgência e emergência. Trata-se de estudo qualitativo, descritivo e exploratório. Participaram dez enfermeiros que trabalham em um serviço de urgência e emergência. As informações foram obtidas por meio de entrevistas semiestruturadas e analisadas pela proposta operativa de Minayo, emergindo dois temas: liderança do enfermeiro na urgência e emergência e estratégias para o exercício da liderança na urgência e emergência, como conversa/diálogo, trabalho em equipe e escuta. Identificou-se que os enfermeiros optam por utilizar um estilo participativo e dialógico, mesmo sendo um serviço muito dinâmico e corrido. Evidenciou-se, também, a carência e a necessidade da instituição de ter um profissional especializado na área da saúde psíquica, para realizações de dinâmicas em grupo, tornando o ambiente de trabalho mais agradável e confortável para o trabalhador. A liderança dialógica poderá auxiliar o enfermeiro no gerenciamento do cuidado e da equipe de enfermagem, por meio do estabelecimento de relações horizontalizadas que promovam a coparticipação de todos os envolvidos.

  7. MIMI: Multimodality, Multiresource, Information Integration Environment for Biomedical Core Facilities

    OpenAIRE

    Szymanski, Jacek; Wilson, David L.; Zhang, Guo-Qiang

    2007-01-01

    The rapid expansion of biomedical research has brought substantial scientific and administrative data management challenges to modern core facilities. Scientifically, a core facility must be able to manage experimental workflow and the corresponding set of large and complex scientific data. It must also disseminate experimental data to relevant researchers in a secure and expedient manner that facilitates collaboration and provides support for data interpretation and analysis. Administrativel...

  8. Rehabilitation of patients with laryngeal and lung cancer after radiotherapy

    International Nuclear Information System (INIS)

    Strashinin, A.I.; Gerasimyak, V.G.; Vladimirova, V.A.; Ivanova, L.V.

    1980-01-01

    The ways of medical and social-occupational rehabilitation after a course of radiotherapy in patients with respiratory system cancer have been determined. Medical rehabilitation in patients with lung cancer comprises expedient planning of radiotherapy by means of systematic medicamental treatment. It is shown that it is necessary to place the patients in special rehabilitation departments after radiotherapy of carry out the treatment of pneumonities

  9. Top-Level Software for VVER-1000 In-core Monitoring System under Implementation of Expanded Nuclear Fuel Diversification Program in Ukraine

    International Nuclear Information System (INIS)

    Khalimonchuk, V.A.

    2015-01-01

    The paper considers the possibility and expediency of developing mathematical software for VVER-1000 ICMS in Ukraine. This mathematical software is among the most important conditions for implementation of the expanded nuclear fuel diversification program. The top-level software is to be developed based on SSTC own studies in the development of codes for power distribution recovery, which were successfully used previously for RBMK-1000 safety analysis

  10. The office surgical suite: pros and cons.

    Science.gov (United States)

    Simons, R L

    1980-05-01

    Today interest and enthusiasm regarding facial plastic surgery is burgeoning. Office surgery provides a new, more expedient, comfortable method of delivery of health care while directly responding to the growing concern among the public and government for improved cost containment of medical services. Awareness of improved surgical techniques and facilities will help to ensure tomorrow's continued growth and satisfaction for both the surgeon and his patient.

  11. Increase of Bio-Gas Power Potential

    OpenAIRE

    V. A. Sednin; О. F. Kraetskaya; I. N. Prokoрenia

    2012-01-01

    The paper presents a review of industrial technologies for obtaining gas-synthesis which is applicable for bio-gas enrichment process. Comparative characteristics are given in the paper. The paper thoroughly considers a technology of dry methane conversion as the most expedient variant recommended for the application in this case. The bio-gas enrichment carried out during its production expands possibilities and efficiency of its application.

  12. Experimental investigation of a small-sized betatron with superposed magnetization

    International Nuclear Information System (INIS)

    Kas'yanov, V.A.; Rychkov, M.V.; Filimonov, A.A.; Furman, Eh.G.; Chakhlov, V.L.; Chertov, A.S.; Shtejn, M.M.

    2001-01-01

    The aim of the paper is to study possibilities of small-sized betatrons (SSB) with direct current superposed magnetization (DSM). It is shown that DSM permits to decrease the SSB weight and cost of the electromagnet and capacitor storage and to shape the prolonged beam dump. It is noted that the DSM realization has the most expediency in SSB operating in a short-time mode [ru

  13. INTRODUCTION OF TAX TOBINA AT THE FINANCIAL AND CREDIT MARKET IN THE CONDITIONS OF CRISIS OF TRUST TO BANKING SYSTEM OF EUROAREA AND GROWTH OF DEFICIT OF STATE FINANCES

    Directory of Open Access Journals (Sweden)

    T. Kolyada

    2013-07-01

    Full Text Available In the article arguments are analysed in relation to determination of expedience of introduction of Tobin’s tax at the financial and credit market in the conditions of crisis of trust to the banking system of Eurozone and growth of volumes of deficit of state finances, and prognoses are done for adaptation of the Ukrainian banking system to the new operating conditions.

  14. Neuroradiology in psychiatry

    International Nuclear Information System (INIS)

    Decker, K.

    1981-01-01

    The various radiological problems in psychiatric hospitals are discussed. The patients in whom positive radiological findings are to be expected are described. The frequency of unexpected radiological findings which can be demonstrated in psychiatric patients with organic brain disease are emphasized. The equipment of radiology departments in psychiatric and regional hospitals is studied with regard to expediency and appropriate recommendations are made. (orig.) [de

  15. Climb Every Mountain: Graduates Urged To Seek Basic Human Values.

    Science.gov (United States)

    Jelinek, James John

    College graduates face the contradictory and inconsistent beliefs of a society that seems to be struggling between a desire to either degrade or enhance the dignity of man. Amid all the current mechanical marvels there exists social ills of nightmare proportions. In the turmoil to find solutions to the many problems many have lost sight of the…

  16. Domestic energy sources urged as Middle East situation heats up

    International Nuclear Information System (INIS)

    Rodgers, L.M.

    1990-01-01

    This article discusses the alternatives to foreign oil as an energy source for the US in the light of the invasion of Kuwait by Iraq. Topics addressed include the responses of organizations representing various energy sources, the public response of the Department of Energy, the response of conservation advocates, and the Administration's reaction

  17. Setting Sail for that Country: The Utopian Urge behind Inclusion

    Science.gov (United States)

    McMaster, Christopher

    2013-01-01

    The vision for the future embedded in inclusive values has fuelled educational reform. This paper will explore the utopian drive behind inclusion. The contributions of thinkers as diverse as John Dewey, Antonio Gramsci, and Paulo Freire give impetus to efforts to create a better tomorrow. They, and those who have previously struggled for…

  18. Urging medical students to publish: Advantages, disadvantages and new challenges.

    Science.gov (United States)

    Rached, Gaëlle; Hobeika, Charbel; Karam, Elias; Kourié, Hampig Raphael; Kattan, Joseph

    2018-06-01

    As soon as they get accepted into medical school, students find themselves facing numerous expectations: coping with tremendous study burden, competing with others for the best rank, completing internships and participating in the race for publishing are only to name a few. This big juggle makes it hard for the medical student to focus on research. It is often easier to postpone publication and involvement in research to "later". In fact there are many advantages to publishing in the current publication system but there are many disadvantages as well. With the widespread of social media and open access systems, new challenges have arisen. The aim of this paper is to discuss the advantages and disadvantages of publishing in the current system while highlighting the new challenges that the students might need to overcome. Its aim is to provide medical students with information to enhance their understanding of the current publication system and thus most importantly, probe their desire to publish. Copyright © 2018 Société Française du Cancer. Published by Elsevier Masson SAS. All rights reserved.

  19. Urges use of renewable energy sources to generate electric power

    International Nuclear Information System (INIS)

    Santizo, Rodolfo

    2001-01-01

    The article discusses the following issues of generation of electric power through renewable energy sources like geothermal and wind energy. The author that is the actual Deputy Minister of Energy and Mines explains the needs of Guatemala in the sector of energy in promoting the renewable energy sources such as wind and geothermal energy because Guatemala has a potential generation by this sources

  20. O Doente Idoso no Serviço de Urgência

    Directory of Open Access Journals (Sweden)

    Pedro Oliveira

    2017-03-01

    Older patients presents higher LOS in the ED, require more immediate attention and required to be admitted in hospital ward more often. With ageing population ED will require to be adapted to their special needs.

  1. The Late Variscan control on the location and asymmetry of the Upper Rhine Graben

    Science.gov (United States)

    Grimmer, J. C.; Ritter, J. R. R.; Eisbacher, G. H.; Fielitz, W.

    2017-04-01

    The NNE-trending Upper Rhine Graben (URG) of the European Cenozoic Rift System developed from c. 47 Ma onwards in response to changing lithospheric stresses in the northwestern foreland of the Alps. The composite graben structure consists of three segments, each c. 100 km long and 30-40 km wide, but flares to c. 60 km near its southern and to c. 80 km near its northern termination. Normal faulting induced a total extension of 5-8 km of the 1-2 km thick Mesozoic sedimentary Franconian platform and underlying Variscan basement rocks. However, distribution of an up to 3.5 km thick sedimentary graben fill and cumulative displacements near Eastern and Western Main Border fault systems suggest that subsidence of the graben floor and shoulder uplift created strong cross-sectional asymmetries. Cumulative W-down displacements >3 km along strongly segmented transfer faults in the east contrast with E-down displacements emergence of the platform above sea level in late Mesozoic times, the deep-reaching W-dipping "extensional defects" of the East Rhine Detachment exerted a primary lithospheric scale control on both location and cross-sectional asymmetry of the Cenozoic graben structure. NE- and NW-striking, strongly altered and more shallow rooted Permocarboniferous or Mesozoic faults exerted secondary upper crustal controls on transfer faults and the accommodation zones near the terminations and segment boundaries of the URG. Deep crustal to upper lithospheric asymmetries continue to influence the neotectonic setting of the URG, such as westward rising earthquake hypocentres. Seismic activity along the URG appears to be part of a >600 km long zone that delimits the trailing edge of a SW-moving lithospheric block. In the URG area, NE-SW-oriented seismic anisotropy at sublithospheric depths of c. 60-80 km suggest active mantle flow in this direction as a possible driving force for the reactivation of pre-graben lithospheric shear zones.

  2. Thermal maturity and petroleum kitchen areas of Liassic Black Shales (Lower Jurassic) in the central Upper Rhine Graben, Germany

    Science.gov (United States)

    Böcker, Johannes; Littke, Ralf

    2016-03-01

    In the central Upper Rhine Graben (URG), several major oil fields have been sourced by Liassic Black Shales. In particular, the Posidonia Shale (Lias ɛ, Lower Toarcian) acts as excellent and most prominent source rock in the central URG. This study is the first comprehensive synthesis of Liassic maturity data in the URG area and SW Germany. The thermal maturity of the Liassic Black Shales has been analysed by vitrinite reflectance (VRr) measurements, which have been verified with T max and spore coloration index (SCI) data. In outcrops and shallow wells (oil window (ca. 0.50-0.60 % VRr). This maturity is found in Liassic outcrops and shallow wells in the entire URG area and surrounding Swabian Jura Mountains. Maximum temperatures of the Posidonia Shale before graben formation are in the order of 80-90 °C. These values were likely reached during Late Cretaceous times due to significant Upper Jurassic and minor Cretaceous deposition and influenced by higher heat flows of the beginning rift event at about 70 Ma. In this regard, the consistent regional maturity data (VRr, T max, SCI) of 0.5-0.6 % VRr for the Posidonia Shale close to surface suggest a major burial-controlled maturation before graben formation. These consistent maturity data for Liassic outcrops and shallow wells imply no significant oil generation and expulsion from the Posidonia Shale before formation of the URG. A detailed VRr map has been created using VRr values of 31 wells and outcrops with a structure map of the Posidonia Shale as reference map for a depth-dependent gridding operation. Highest maturity levels occur in the area of the Rastatt Trough (ca. 1.5 % VRr) and along the graben axis with partly very high VRr gradients (e.g. well Scheibenhardt 2). In these deep graben areas, the maximum temperatures which were reached during upper Oligocene to Miocene times greatly exceed those during the Cretaceous.

  3. Accidentes de tránsito y el consumo de alcohol en una unidad de urgencia de La Paz, Bolivia Acidentes de trânsito e o consumo de álcool em unidade de urgência de La Paz, Bolívia Traffic accidents and alcohol consumption in an emergency unit of La Paz, Bolivia

    Directory of Open Access Journals (Sweden)

    Inês Magali Pelaez Mariscal

    2010-06-01

    Full Text Available Estudio de tipo cuantitativo, descriptivo, observacional y transversal. El objetivo del estudio fue conocer la distribución y características de los accidentes de tránsito relacionados con el consumo de alcohol en una unidad de urgencias de un hospital de clínicas de La Paz, en Bolivia. La muestra estuvo conformada por 62 personas, choferes y peatones, mayores de 15 años, que estuvieron involucrados en accidentes de tránsito por estado de ebriedad, los cuales acudieron a la Unidad de Urgencias. Fue aplicado una encuesta elaborado por los investigadores para recolectar datos sociodemográficos y de morbilidad de las víctimas y datos que evalúan el consumo de alcohol del conductor responsable del accidente. Los resultados evidenciaron que 71% de los accidentados eran hombres; 32,3% presentaban edades entre 21 y 30 años; 29% eran estudiantes y 25.8% eran choferes. El estudio permitió la caracterización de las personas accidentadas, del consumo de alcohol e del accidente.Este é um estudo tipo quantitativo, descritivo, observacional, transversal. O objetivo foi conhecer a distribuição e as características dos acidentes de trânsito relacionados ao consumo de álcool em unidade de urgência de um hospital de clínicas de La Paz, Bolívia. A amostra foi constituída por 62 pessoas, motoristas e pedestres, maiores de 15 anos, envolvidos em acidentes de trânsito por estado de embriaguez, atendidos na unidade de urgência. Foi aplicado um questionário, elaborado pelos pesquisadores, para coletar dados sociodemográficos e de morbidade da vítima, e dados que avaliam o consumo de álcool do condutor responsável pelo acidente. Os resultados evidenciaram que 71% dos acidentados eram homens, 32,3% apresentavam idade entre 21 e 30 anos, 29% eram estudantes e 25,8% eram motoristas. O estudo permitiu a caracterização das pessoas acidentadas, do consumo de álcool e do acidente.The aim of this quantitative, descriptive, observational, cross

  4. The effects of familiarity on thought--action fusion.

    Science.gov (United States)

    Berman, Noah C; Wheaton, Michael G; Fabricant, Laura E; Jacobson, Spenser R; Abramowitz, Jonathan S

    2011-10-01

    The present study examined whether beliefs about the importance of thoughts (i.e., thought--action fusion; TAF) are related to the target subject of the negative thought. One hundred and seven undergraduate students were randomly assigned to imagine either a beloved relative or a stranger being diagnosed with cancer and provided in vivo ratings of anxiety, likelihood, moral wrongness, urge to neutralize, and how upsetting the event would be if it occurred. Results indicated that thinking of a relative being diagnosed with cancer provoked more distress, urges to neutralize, and higher estimates of likelihood, as well greater use of mental neutralizing behaviors, compared to thinking of a stranger. Contrary to our prediction, the groups did not differ in their ratings of the moral wrongness. These findings broadly support the assertion that the more personally significant a negative intrusive thought, the more it will provoke distress and urges to neutralize. Results are discussed in terms of the cognitive model of obsessions and clinical implications are addressed. Copyright © 2011 Elsevier Ltd. All rights reserved.

  5. A double-blind, placebo-controlled study of the opiate antagonist, naltrexone, in the treatment of kleptomania.

    Science.gov (United States)

    Grant, Jon E; Kim, Suck Won; Odlaug, Brian L

    2009-04-01

    Kleptomania is a rare psychiatric disorder characterized by recurrent stealing and for which there exists no empirically validated treatments. This study examined the efficacy and tolerability of the opioid antagonist naltrexone in adults with kleptomania who have urges to steal. An 8-week, double-blind, placebo-controlled trial was conducted to evaluate the safety and efficacy of oral naltrexone for kleptomania. Twenty-five individuals with DSM-IV kleptomania were randomized to naltrexone (dosing ranging from 50 mg/day to 150 mg/day) or placebo. Twenty-three subjects (92%) completed the study. Subjects were assessed every 2 weeks with the Yale Brown Obsessive Compulsive Scale Modified for Kleptomania (K-YBOCS), the urge and behavior subscales of the K-YBOCS, the Kleptomania Symptom Assessment Scale (K-SAS), the Clinical Global Impressions Scale (CGI), and measures of depression, anxiety, and psychosocial functioning. Subjects assigned to naltrexone had significantly greater reductions in K-YBOCS total scores (p = .001), stealing urges (p = .032), and stealing behavior (p kleptomania severity (reflected in the CGI scores) (p kleptomania. Naltrexone was well tolerated.

  6. Resolving the velocity and strain fields in the Upper Rhine Graben Area from a Combination of Levelling, GNSS and InSAR

    Science.gov (United States)

    Westerhaus, Malte; Fuhrmann, Thomas; Mayer, Michael; Zippelt, Karl; Heck, Bernhard

    2016-04-01

    The Upper Rhine Graben (URG), located in the tri-national region between Germany, France and Switzerland is the most prominent segment of the European Cenozoic rift system. In recent times, the URG area is characterised by small tectonic movements (less than 1 mm/a) and moderate seismicity up to M=5. Historically, earthquake magnitudes exceeding M=6 have been reported showing that the seismic hazard is quite high. The contemporary tectonic surface deformations are superimposed by displacements caused by anthropogenic activities in various locations in the area, such as coal and potash mining, groundwater usage, oil extraction, geothermal energy and CO2 storage. We use data sets from levelling campaigns, InSAR and permanent GNSS sites to raise an inventory of the current 3D surface displacements and strain rates in the URG with high precision and high spatial resolution. Precise levellings carried out by the surveying authorities of Germany, France and Switzerland since the end of the 19th century have been combined to form a network of levelling lines. A kinematic network adjustment is applied on the levelling data, providing an accurate solution for vertical displacement rates at the levelling benchmarks. InSAR is used to fill gaps in the interior of the levelling loops and to significantly increase the number of points. All the available ERS-1/2 and Envisat scenes from two acquisition geometries covering a period from 1992 to 2000 and 2002 to 2010, resp., are processed according to the Persistent-Scatterer approach. In addition, coordinate time series of 76 permanent sites of the GNSS URG Network are used to support the derivation of the horizontal velocity field of the region. Daily GPS-solutions obtained in differential mode are available since 2004. In a first step, estimates of the surface displacement rates are derived from each technique starting from the raw data. Subsequently, the single-technique deformation estimates are mathematically combined to a 3D

  7. Direct Aldehyde C-H Arylation and Alkylation via the Combination of Nickel, Hydrogen Atom Transfer, and Photoredox Catalysis.

    Science.gov (United States)

    Zhang, Xiaheng; MacMillan, David W C

    2017-08-23

    A mechanism that enables direct aldehyde C-H functionalization has been achieved via the synergistic merger of photoredox, nickel, and hydrogen atom transfer catalysis. This mild, operationally simple protocol transforms a wide variety of commercially available aldehydes, along with aryl or alkyl bromides, into the corresponding ketones in excellent yield. This C-H abstraction coupling technology has been successfully applied to the expedient synthesis of the medicinal agent haloperidol.

  8. Emergency Protection from Aerosols

    Energy Technology Data Exchange (ETDEWEB)

    Cristy, G.A.

    2001-11-13

    Expedient methods were developed that could be used by an average person, using only materials readily available, to protect himself and his family from injury by toxic (e.g., radioactive) aerosols. The most effective means of protection was the use of a household vacuum cleaner to maintain a small positive pressure on a closed house during passage of the aerosol cloud. Protection factors of 800 and above were achieved.

  9. Unity of Mission: Civilian-Military Teams in War and Peace

    Science.gov (United States)

    2016-04-01

    cancel extreme scores, the process reduced subjective bias . We used the mean as a proxy for the team’s consensus on Anbar’s quarterly progress...Afghanistan have demonstrated, the custom- ary US bias toward hard power in general, albeit expedient and more 196 │ HOLSHEK manageable and measurable...even if he does want to help, possibly cannot even communicate to a superior to get a decision. Again, headquarters consciously or subconsciously

  10. Economic Experience in Creation and Operation of Commercial Propulsion Nuclear Plants. Annex VII

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-12-15

    This annex considers the reduction of capital costs in commercial nuclear power by employing commercial scale production and common technologies of equipment design and fabrication, based on the vast production and operation experience of Russian Federation nuclear propulsion plants. The performed consideration proves the expediency of adopting the most effective engineering solutions and approaches used for production of propulsion nuclear plants in the production of commercial nuclear power plants.

  11. Update heat exchanger designing principles

    International Nuclear Information System (INIS)

    Lipets, A.U.; Yampol'skij, A.E.

    1985-01-01

    Update heat exchanger design principles are analysed. Different coolant pattern in a heat exchanger are considered. It is suggested to rationally organize flow rates irregularity in it. Applying on heat exchanger designing measures on using really existing temperature and flow rate irregularities will permit to improve heat exchanger efficiency. It is expedient in some cases to artificially produce irregularities. In this connection some heat exchanger design principles must be reviewed now

  12. The Governor's Challenge: "Building a Stronger Virginia Today": Transportation Visions and Solutions

    Science.gov (United States)

    Baker, Susan

    2008-01-01

    Using STM(Science, Technology, Engineering, Math) education, this emerging workforce will have the chance to creatively solve one of Virginia's biggest challenges: TRANSPORTATION. - Students will be asked to develop alternative transportation systems for the state. This competition will enable teams to work with business mentors to design creative solutions for regional gridlocks and develop other transportation systems to more easily and expediently reach all parts of the Commonwealth.

  13. The use of socio-communication technologies in the process of popularization of sports practices

    Directory of Open Access Journals (Sweden)

    A. N. Batuk

    2014-04-01

    For successful implementation of the tasks used not one, but several information collection methods. The question on expediency of one or the other method depends The implementation of each of the offered directions requires development (adaptation of a specific socio­technological approaches (methods and on the basis of a Toolkit for the successful implementation of specific social technologists on the specific characteristics of the object of research.

  14. RESEARCH OF HEAT-RESISTANT CONCRETE ON THE BASIS OF BASALT FILLER FOR CONCRETING OF METAL DESIGNS

    Directory of Open Access Journals (Sweden)

    R. M. Curbanov

    2013-01-01

    Full Text Available Expediency of use of heat-resistant concrete locates in article on the basis of a basalt filler. It is thin a ground additive promotes increase in power of internal friction between material particles. With increase in power of internal friction between particles viscosity knitting increases and as a result ryazmyagcheniye temperature under loading increases and fire resistance of a material increases

  15. High-power condensation turbine application to district heating

    International Nuclear Information System (INIS)

    Virchenko, M.A.; Arkad'ev, B.A.; Ioffe, V.Yu.

    1982-01-01

    In general outline the role of condensation turbines in NPP district heating is considered. The expediency of expansion of central heating loading of turbines of operating as well as newly designed condensation power plants on the basis of the WWER-1000-type reactors is shown. The principle heat flowsheet of the 1000 MW power turbine is given. An advantage in using turbines with uncontrolled steam bleeding is pointed out [ru

  16. Use orotic acid in the treatment of pathological conditions associated with hyperuricemia

    Directory of Open Access Journals (Sweden)

    D.D. Ivanov

    2014-10-01

    Full Text Available Hyperuricemia - a condition characterized by elevated relative to normal ranges, levels of uric acid in the blood. Among the diseases caused by hyperuricemia, most noteworthy are gout, urate nephropathy, and urolithiasis. The topic of this article is devoted to the comparative characteristics of drugs used to correct hyperuricemia. The main part of the article is an analysis of pharmacodynamics, efficacy, safety and expediency of using orotic acid agents.

  17. Emergency protection from aerosols

    International Nuclear Information System (INIS)

    Cristy, G.A.; Chester, C.V.

    1981-07-01

    Expedient methods were developed that could be used by an average person, using only materials readily available, to protect himself and his family from injury by toxic (e.g., radioactive) aerosols. The most effective means of protection was the use of a household vacuum cleaner to maintain a small positive pressure on a closed house during passage of the aerosol cloud. Protection factors of 800 and above were achieved

  18. What does a study of nonsteroidal anti-inflammatory drug sales statistics give the Russian Federation?

    Directory of Open Access Journals (Sweden)

    Viktoriya Georgievna Barskova

    2011-01-01

    Full Text Available The paper analyzes the data obtained by Pharmexpert on the sales of nonsteroidal anti-inflammatory drugs in the Russian Federation. Ibuprofen, ketorolac, diclofenac, and nimesulide are sales leaders. Possible reasons for the popularity of a number of medications and whether it is expedient to use intramuscular formulations are considered. The WHO data on indi-cations for and contraindications to the use of injectable dosage form are given.

  19. Optimizing Security of Cloud Computing within the DoD

    Science.gov (United States)

    2010-12-01

    expediency in new service roll out, availability (a loss of one component will not disconnect all components), and mobility (the ability to telecommute ).30...practices as well as oversight of administrative privileges and access.129  Scarce federal security guidance/procurement strategy. Comprehensive...systems; the intent of the program is to provide oversight without duplication of effort.258 The CCAC president is calling FedRAMP a “unified, risk

  20. “Situação difícil aquele tempo”: Mundos dos trabalhadores e movimentos da memória, Fernandópolis (1946-1964

    Directory of Open Access Journals (Sweden)

    Vagner José Moreira

    2010-06-01

    Full Text Available The article discusses the workers' worlds and the history of the production of memoirs on the social movements in the country, expressed in the social experience, in Fernandópolis-SP, from 1946 to 1964. The production of social memory in this politically disqualify the struggles of workers in the present and in the past, using various expedients, such as the criminalization of the workers' social movements.

  1. Implementation of the Quality Management System in the telecommunications companies

    OpenAIRE

    Menshikova Ekaterina; Khazanov Oleg; Styazhkin Mark

    2016-01-01

    This article describes the advantages of the implementing of the quality management system based on ISO 9001 in the telecommunications companies. The stages of the implementation of the quality management system in the telecommunications companies are discussed. The map of the main process and criteria of processes is developed. The expediency of implementing the quality management system based on the requirements of ISO 9001 in Telecommunications is showed.

  2. CALCULATION PECULIARITIES OF RE-PROCESSED ROAD COVERING UNIT COST

    Directory of Open Access Journals (Sweden)

    Dilyara Kyazymovna Izmaylova

    2017-09-01

    Full Text Available In the article there are considered questions of economic expediency of non-waste technology application for road covering repair and restoration. Determined the conditions of asphalt-concrete processing at plants. Carried out cost changing analysis of asphalt granulate considering the conditions of transportation and preproduction processing. Given an example of expense calculation of one conventional unit of asphalt-concrete mixture volume preparation with and without processing.

  3. Increase of Bio-Gas Power Potential

    Directory of Open Access Journals (Sweden)

    V. A. Sednin

    2012-01-01

    Full Text Available The paper presents a review of industrial technologies for obtaining gas-synthesis which is applicable for bio-gas enrichment process. Comparative characteristics are given in the paper. The paper thoroughly considers a technology of dry methane conversion as the most expedient variant recommended for the application in this case. The bio-gas enrichment carried out during its production expands possibilities and efficiency of its application.

  4. Differentiated Learning. Teaching English to Mixed-Ability Classes

    Directory of Open Access Journals (Sweden)

    Lăcrimioara Năsui

    2015-06-01

    Full Text Available The present article is dedicated to one of the most important aspects of teaching nowadays- differentiated teaching and instruction for English language learners. Differentiation means directing teaching towards the interests and capacities of all pupils in a class. It is not a simple expedient for keeping pupils busy – although that may prove important – it is a consideration for overcoming any latent barriers to learning.

  5. Synthesis and Characterization of Stimuli-Responsive Poly(2-dimethylamino-ethylmethacrylate)-Grafted Chitosan Microcapsule for Controlled Pyraclostrobin Release

    OpenAIRE

    Chunli Xu; Lidong Cao; Pengyue Zhao; Zhaolu Zhou; Chong Cao; Feng Zhu; Fengmin Li; Qiliang Huang

    2018-01-01

    Controllable pesticide release in response to environmental stimuli is highly desirable for better efficacy and fewer adverse effects. Combining the merits of natural and synthetic polymers, pH and temperature dual-responsive chitosan copolymer (CS-g-PDMAEMA) was facilely prepared through free radical graft copolymerization with 2-(dimethylamino) ethyl 2-methacrylate (DMAEMA) as the vinyl monomer. An emulsion chemical cross-linking method was used to expediently fabricate pyraclostrobin micro...

  6. Some aspects of fast reactor economics

    International Nuclear Information System (INIS)

    Kazachkovskij, O.D.

    1996-01-01

    Expedient approach to evaluation of economic efficiency of fast reactors is discussed. It is concluded that determination of electric power generation cost should be based on the fact, that plutonium cost is dictated only by expenses for its extraction from the spent fuel. The cost of the first critical load is not included into capital investments, and investment charges should be sufficiently lower, than standard ones. 5 refs

  7. Quantitation of anticonvulsant drugs in serum by gas-chromatography on the stationary phase SP-2510.

    Science.gov (United States)

    Godolphin, W; Thoma, J

    1978-03-01

    A new column packing, SP-2510 DA (Supelco, Inc., Bellefonte, Pa. 16823), is an excellent stationary phase for the determination of a wide variety of anticonvulsant drugs by gas--liquid chromatography without derivatization. However, when uncomplicated extraction procedures are used, serum cholesterol interferes with the determination of primidone. By the simple expedient of adding a short "pre-column" containing another phase (SP-2250 DA) the problem is overcome.

  8. [Endoscopic sclerotherapy in the combined treatment of portal hypertension in children].

    Science.gov (United States)

    Ul'rikh, E V; Korolev, M P; Kupatadze, F D; Sevriugov, B L; Nabokov, V V

    1992-01-01

    The authors have performed 28 sessions of endoscopic sclerotherapy of dilated esophagus veins in children. The 70% ethyl alcohol was used. Six sessions were carried out in patients with gastroesophageal hemorrhage. In 22 patients the sclerotherapy was carried on according to plan. The fiber gastroscope with a standard injector was used. A conclusion is made of expediency of using endoscopic sclerotherapy in complex treatment of portal hypertension in children.

  9. The Use of Virtual Reality to Facilitate Mindfulness Skills Training in Dialectical Behavioral Therapy for Borderline Personality Disorder: A Case Study

    Science.gov (United States)

    Nararro-Haro, Maria V.; Hoffman, Hunter G.; Garcia-Palacios, Azucena; Sampaio, Mariana; Alhalabi, Wadee; Hall, Karyn; Linehan, Marsha

    2016-01-01

    Borderline personality disorder (BPD) is a severe mental disorder characterized by a dysfunctional pattern of affective instability, impulsivity, and disturbed interpersonal relationships. Dialectical Behavior Therapy (DBT®) is the most effective treatment for Borderline Personality Disorder, but demand for DBT® far exceeds existing clinical resources. Most patients with BPD never receive DBT®. Incorporating computer technology into the DBT® could help increase dissemination. Immersive Virtual Reality technology (VR) is becoming widely available to mainstream consumers. This case study explored the feasibility/clinical potential of using immersive virtual reality technology to enhance DBT® mindfulness skills training of a 32 year old female diagnosed with BPD. Prior to using VR, the patient experienced difficulty practicing DBT® mindfulness due to her emotional reactivity, and difficulty concentrating. To help the patient focus her attention, and to facilitate DBT® mindfulness skills learning, the patient looked into virtual reality goggles, and had the illusion of slowly “floating down” a 3D computer-generated river while listening to DBT® mindfulness training audios. Urges to commit suicide, urges to self harm, urges to quit therapy, urges to use substances, and negative emotions were all reduced after each VR mindfulness session and VR mindfulness was well accepted/liked by the patient. Although case studies are scientifically inconclusive by nature, results from this feasibility study were encouraging. Future controlled studies are needed to quantify whether VR-enhanced mindfulness training has long term benefits e.g., increasing patient acceptance and/or improving therapeutic outcome. Computerizing some of the DBT® skills treatment modules would reduce cost and increase dissemination. PMID:27853437

  10. The Nature of Evolution: A Study on the Philosophy of A.M. Iqbal

    Directory of Open Access Journals (Sweden)

    Imam Bahroni

    2012-06-01

    Full Text Available The nature of human being evolution in the philosophy of AllamaMuhammad Iqbal is different from the conception of other modernphilosophers. This natural evolution basically springs from the real Love whichflourishes in the inner being of an individual.Love as described by Iqbal is not physical, sexual or biological principle.It is the inward drive of all life to attain to its full maturity and development. Itis a primal urge to live, to progress and bring out all the inner wealth andresources of being. Every phenomenon and activity that is not related to thisprimal urge and does not subserve its purposes, leads to stagnation and decay.He voices strong condemnation of scientific reason, arts and religion whenthey carve out for themselves autonomous fields of action or set themselvesup as independent forces. According to Iqbal, all specialized activity, whether itis intellectual, artistic or religious, is a differentiation of the primal urge whichhe calls Love and apart from it has no title to independent, autonomous existence.Iqbal further explains that a philosophy which does not spring from thedepth of life is so much empty trash; and thought which is not inspired by loveor the will to progress, construct, create and beautify the world is dreadening.Similarly a religion without the flame of love of the urge to advance, improveand enrich life is only lifeless ritualism. Disbelief and atheism are as good asIslam, if inflamed by love, while Islam is no better than paganism if it is devoid of Love.

  11. The Use of Virtual Reality to Facilitate Mindfulness Skills Training in Dialectical Behavioral Therapy for Borderline Personality Disorder: A Case Study.

    Science.gov (United States)

    Nararro-Haro, Maria V; Hoffman, Hunter G; Garcia-Palacios, Azucena; Sampaio, Mariana; Alhalabi, Wadee; Hall, Karyn; Linehan, Marsha

    2016-01-01

    Borderline personality disorder (BPD) is a severe mental disorder characterized by a dysfunctional pattern of affective instability, impulsivity, and disturbed interpersonal relationships. Dialectical Behavior Therapy (DBT®) is the most effective treatment for Borderline Personality Disorder, but demand for DBT® far exceeds existing clinical resources. Most patients with BPD never receive DBT®. Incorporating computer technology into the DBT® could help increase dissemination. Immersive Virtual Reality technology (VR) is becoming widely available to mainstream consumers. This case study explored the feasibility/clinical potential of using immersive virtual reality technology to enhance DBT® mindfulness skills training of a 32 year old female diagnosed with BPD. Prior to using VR, the patient experienced difficulty practicing DBT® mindfulness due to her emotional reactivity, and difficulty concentrating. To help the patient focus her attention, and to facilitate DBT® mindfulness skills learning, the patient looked into virtual reality goggles, and had the illusion of slowly "floating down" a 3D computer-generated river while listening to DBT® mindfulness training audios. Urges to commit suicide, urges to self harm, urges to quit therapy, urges to use substances, and negative emotions were all reduced after each VR mindfulness session and VR mindfulness was well accepted/liked by the patient. Although case studies are scientifically inconclusive by nature, results from this feasibility study were encouraging. Future controlled studies are needed to quantify whether VR-enhanced mindfulness training has long term benefits e.g., increasing patient acceptance and/or improving therapeutic outcome. Computerizing some of the DBT® skills treatment modules would reduce cost and increase dissemination.

  12. The role of interpersonal conflict and perceived social support in nonsuicidal self-injury in daily life.

    Science.gov (United States)

    Turner, Brianna J; Cobb, Rebecca J; Gratz, Kim L; Chapman, Alexander L

    2016-05-01

    Although accumulating microlongitudinal research has examined emotion regulatory models of nonsuicidal self-injury (NSSI), few studies have examined how interpersonal contingencies influence daily NSSI behavior. Participants with repeated NSSI (N = 60) provided daily ratings of perceived social support, interpersonal conflict, and NSSI urges and behaviors for 14 days. Consistent with interpersonal models of NSSI, we hypothesized that participants would be more likely to engage in NSSI on days when they experienced high levels of interpersonal conflict, that NSSI acts that were revealed to others would be followed by desirable interpersonal changes (i.e., greater support, less conflict), and that these interpersonal changes would, in turn, predict stronger NSSI urges and more frequent NSSI behavior. Consistent with hypotheses, daily conflict was associated with stronger same-day NSSI urges and greater likelihood of NSSI acts. Perceived support increased following NSSI acts that had been revealed to others, but not unrevealed NSSI acts. This perceived support was, in turn, associated with a stronger NSSI urges and greater likelihood of engaging in NSSI on the following day. Moreover, participants whose NSSI was revealed to others engaged in more total NSSI acts during the diary period than those whose NSSI was not revealed to others. Inconsistent with hypotheses, interpersonal conflict did not decrease following NSSI, regardless of whether or not these acts were revealed to others. Together, these results provide preliminary support for interpersonal reinforcement models of NSSI and highlight the importance of expanding research in this area to include interpersonal contingencies that may influence this behavior. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  13. An Expedient but Fascinating Geophysical Chimera: The Pinyon Flat Seismic Strain Point Array

    Science.gov (United States)

    Langston, C. A.

    2016-12-01

    The combination of a borehole Gladwin Tensor Strain Meter (GTSM) and a co-located three component broadband seismometer (BB) can theoretically be used to determine the propagation attributes of P-SV waves in vertically inhomogeneous media such as horizontal phase velocity and azimuth of propagation through application of wave gradiometry. A major requirement for this to be successful is to have well-calibrated strain and seismic sensors to be able to rely on using absolute wave amplitude from both systems. A "point" seismic array is constructed using the PBO GTSM station B084 and co-located BB seismic stations from an open array experiment deployed by UCSD as well as PFO station at the Pinyon Flat facility. Site amplitude statics for all three ground motion components are found for the 14-element (13 PY stations + PFO), small aperture seismic array using data from 47 teleseisms recorded from 2014 until present. Precision of amplitude measurement at each site is better than 0.2% for vertical components, 0.5% for EW components, and 1% for NS components. Relative amplitudes among sites of the array are often better than 1% attesting to the high quality of the instrumentation and installation. The wavefield and related horizontal strains are computed for the location of B084 using a second order Taylor's expansion of observed waveforms from moderate ( M4) regional events. The computed seismic array areal, differential, and shear strains show excellent correlation in both phase and amplitude with those recorded by B084 when using the calibration matrix previously determined using teleseismic strains from the entire ANZA seismic network. Use of the GTSM-BB "point" array significantly extends the bandwidth of gradiometry calculations over the small-aperture seismic array by nearly two orders of magnitude from 0.5 Hz to 0.01 Hz. In principle, a seismic strain point array could be constructed from every PBO GTSM with a co-located seismometer to help serve earthquake early warning for large regional events on North America's west coast.

  14. Estimating fine-scale land use change dynamics using an expedient photointerpretation-based method

    Science.gov (United States)

    Tonya Lister; Andrew Lister; Eunice Alexander

    2009-01-01

    Population growth and urban expansion have resulted in the loss of forest land. With growing concerns about this loss and its implications for global processes and carbon budgets, there is a great need for detailed and reliable land use change data. Currently, the Northern Research Station uses an Annual Inventory design whereby all plots are revisited every 5 years...

  15. Iridium-Catalyzed Dynamic Kinetic Isomerization: Expedient Synthesis of Carbohydrates from Achmatowicz Rearrangement Products.

    Science.gov (United States)

    Wang, Hao-Yuan; Yang, Ka; Bennett, Scott R; Guo, Sheng-rong; Tang, Weiping

    2015-07-20

    A highly stereoselective dynamic kinetic isomerization of Achmatowicz rearrangement products was discovered. This new internal redox isomerization provided ready access to key intermediates for the enantio- and diastereoselective synthesis of a series of naturally occurring sugars. The nature of the de novo synthesis also enables the preparation of both enantiomers. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. Preparation of fluconazole buccal tablet and influence of formulation expedients on its properties.

    Science.gov (United States)

    Mohamed, Saifulla P; Muzzammil, Shariff; Pramod, Kumar T M

    2011-04-01

    The aim of present study was to prepare buccal tablets of fluconazole for oral candidiasis. The dosage forms were designed to release the drug above the minimum inhibitory concentration for prolonged period of time so as to reduce the frequency of administration and to overcome the side effects of systemic treatment. The buccal tablets were prepared by using Carbopol 71G and Noveon AA-1 by direct compression method. Microcrystalline cellulose was used as the filler and its effect was also studied. The prepared dosage forms were evaluated for physicochemical properties, in vitro release studies and mucoadhesive properties using sheep buccal mucosa as a model tissue. Tablets containing 50% of polymers (Carbopol & Noveon) were found to be the best with moderate swelling along with favorable bioadhesion force, residence time and in vitro drug release. The in vitro drug release studies revealed that drug released for 8 h, which in turn may reduce dosing frequency and improved patient compliance in oral candidiasis patients.

  17. Fiberglass-Reinforced Rigid Polyurethane Expedient Pavement Subject to Simulated F-4 Aircraft Traffic.

    Science.gov (United States)

    1980-05-01

    34 4,. * ., Table B-I. CPR-739 Rigid Polyurethane Foam Component Characteristics [ Cream Time, 120 sec; Rise Time, 13 sec; Cure Time, 24 hr at 750F...INC. E Colic Soil Tech Dept. Pennsauken. NJ SANDIA LABORATORIES Library Div., Livermore CA SCHUPACK ASSOC SO. NORWALK. CT (SCHUPACK) SHELL OIL CO

  18. Laboratory Evaluation of Expedient Low-Temperature Admixtures for Runway Craters in Cold Weather

    Science.gov (United States)

    2014-10-01

    it consists of a pre- blend of Type III Portland cement (calcium sulfoaluminate [CSA] cement with some small amount of admixtures for workability...more information on similar crater repair methods, equipment, and materials used by the U.S. Ar- my, see Center for Army Lessons Learned (2011). ERDC...all measurements with a TA Instrument TAM Air isothermal calorimeter operated at 23°C. To capture the initial wetting of the cement and early-age

  19. Political expediency and the rule of law in Africa: A focus on selected ...

    African Journals Online (AJOL)

    Beginning in the late 1980s and due to a confl uence of domestic and international forces, Africa's political realities began changing, resulting in good governance, including the rule of law taking centre stage in both the discourse and practice of post-Cold War African politics. However, in some cases the continent's ...

  20. Spreading depression analysis of contact behaviour of rats.

    Science.gov (United States)

    Tikal, K

    1977-08-01

    Social contact behaviour induced by spreading cortical depression was studied in rats. The controls looked for and remained in contact, whereas between the rats with spreading cortical depression and their other partners there was no contact. This phenomenon is due mainly to the absence of an active urge for contact. The contact behaviour of rats is evidently controlled by the cerebral cortex or by subcortical areas of the brain which are inhibited after the elicitation of spreading depression. The experiments show that the contact behaviour of rats has at least two components - an active urge for contact and passive tolerance of contact.