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Sample records for key design features

  1. Overall Design Features and Key Technology Development for KJRR

    Energy Technology Data Exchange (ETDEWEB)

    Park, C.; Lee, B. C.; Ryu, J. S.; Kim, Y. K. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    The KJRR (Ki-Jang Research Reactor) project was launched on Apr., 2012; 1) to make up the advanced technology related to RRs, 2) to provide the self-sufficiency in terms of medical and industrial radioisotope (RI) supply, and 3) to enlarge the NTD silicon doping services for growing the power device industry. The major facilities to be built through the KJRR project are, • 15 MW Research Reactor and Reactor building • Radioisotopes Production Facility (RIPF) and related R and D Facility • Fission Mo Production Facility (FMPF) with LEU Target • Radio-waste Treatment Facility (RTF) • Neutron Irradiation Facility such as PTS and HTS. This paper describes the overall design features of the KJRR and the key technology development for RRs during the project. The overall design features of the KJRR and RR technology under development have been overviewd. The design of the KJRR will comply with the Korean Nuclear Law, regulatory requirements and guidelines as well as international standards and guidelines. The KJRR is expected to be put into operation in the middle of 2019.

  2. Key enabling design features of the ITER HNB Duct Liner

    Energy Technology Data Exchange (ETDEWEB)

    Chuilon, Ben, E-mail: ben.chuilon@ccfe.ac.uk; Mistry, Sanjay; Andrews, Rodney; Verhoeven, Roel; Xue, Yongkuan

    2015-10-15

    Highlights: • Key engineering design details of the ITER HND Duct Liner are presented. • A standardised CuCrZr water cooled panel that can be remotely handled is detailed. • Bolts are protected from beam power by means of a tungsten cap to radiate heat away. • Water connections placed coaxially are protected from beam power by a tungsten ring. • Explosion-bonded CuCrZr-316L panels result in a tenfold disruption torque reduction. - Abstract: The Duct Liner (DL) for the ITER Heating Neutral Beam (HNB) is a key component in the beam transport system. Duct Liners installed into equatorial ports 4 and 5 of the Vacuum Vessel (VV) will protect the port extension from power deposition due to re-ionisation and direct interception of the HNB. Furthermore, the DL contributes towards the shielding of the VV and superconducting coils from plasma photons and neutrons. The DL incorporates a 316L(N)-IG, deep-drilled and water cooled Neutron Shield (NS) whose internal walls are lined with actively cooled CuCrZr Duct Liner Modules (DLMs). These Remote Handling Class 2 and 3 panels provide protection from neutral beam power. This paper provides an overview of the preliminary design for the ITER HNB DL and focusses on critical features that ensure compatibility with: high heat flux requirements, remote maintenance procedures, and transient magnetic fields arising from major plasma disruptions. The power deposited on a single DLM can reach 300 kW with a peak power density of 2.4 MW/m{sup 2}. Feeding coolant to the DLMs is accomplished via welded connections to the internal coolant network of the NS. These are placed coaxially to allow for thermal expansion of the DLMs without the use of deformable connections. Critically, the remote maintenance of individual DLMs necessitates access to water connections and bolts from the beam facing surface, thus subjecting them to high heat flux loads. This design challenge will become more prevalent as fusion devices become more powerful

  3. Preliminary safety analysis for key design features of KALIMER

    Energy Technology Data Exchange (ETDEWEB)

    Hahn, D. H.; Kwon, Y. M.; Chang, W. P.; Suk, S. D.; Lee, S. O.; Lee, Y. B.; Jeong, K. S

    2000-07-01

    KAERI is currently developing the conceptual design of a liquid metal reactor, KALIMER(Korea Advanced Liquid Metal Reactor) under the long-term nuclear R and D program. In this report, descriptions of the KALIMER safety design features and safety analyses results for selected ATWS accidents are presented. First, the basic approach to achieve the safety goal is introduced in chapter 1, and the safety evaluation procedure for the KALIMER design is described in chapter 2. It includes event selection, event categorization, description of design basis events, and beyond design basis events. In chapter 3, results of inherent safety evaluations for the KALIMER conceptual design are presented. The KALIMER core and plant system are designed to assure design performance during a selected set of events without either reactor control or protection system intervention. Safety analyses for the postulated anticipated transient without scram(ATWS) have been performed to investigate the KALIMER system response to the events. They are categorized as bounding events(BEs) because of their low probability of occurrence. In chapter 4, the design of the KALIMER containment dome and the results of its performance analysis are presented. The designs of the existing LMR containment and the KALIMER containment dome have been compared in this chapter. Procedure of the containment performance analysis and the analysis results are described along with the accident scenario and source terms. Finally, a simple methodology is introduced to investigate the core kinetics and hydraulic behavior during HCDA in chapter 5. Mathematical formulations have been developed in the framework of the modified bethe-tait method, and scoping analyses have been performed for the KALIMER core behavior during super-prompt critical excursions.

  4. Safety analysis for key design features of KALIMER-600 design concept

    International Nuclear Information System (INIS)

    Lee, Yong-Bum; Kwon, Y. M.; Kim, E. K.; Suk, S. D.; Chang, W. P.; Joeng, H. Y.; Ha, K. S.; Heo, S.

    2005-03-01

    KAERI is developing the conceptual design of a Liquid Metal Reactor, KALIMER-600 (Korea Advanced LIquid MEtal Reactor) under the Long-term Nuclear R and D Program. KALIMER-600 addresses key issues regarding future nuclear power plants such as plant safety, economics, proliferation, and waste. In this report, key safety design features are described and safety analyses results for typical ATWS accidents, containment design basis accidents, and flow blockages in the KALIMER design are presented. First, the basic approach to achieve the safety goal and main design features of KALIMER-600 are introduced in Chapter 1, and the event categorization and acceptance criteria for the KALIMER-600 safety analysis are described in Chapter 2, In Chapter 3, results of inherent safety evaluations for the KALIMER-600 conceptual design are presented. The KALIMER-600 core and plant system are designed to assure benign performance during a selected set of events without either reactor control or protection system intervention. Safety analyses for the postulated anticipated transient without scram (ATWS) have been performed using the SSC-K code to investigate the KALIMER-600 system response to the events. The objectives of Chapter 4, are to assess the response of KALIMER-600 containment to the design basis accidents and to evaluate whether the consequences are acceptable or not in the aspect of structural integrity and the exposure dose rate. In Chapter 5, the analysis of flow blockage for KALIMER-600 with the MATRA-LMR-FB code, which has been developed for the internal flow blockage in a LMR subassembly, are described. The cases with a blockage of 6-subchannel, 24-subchannel, and 54-subchannel are analyzed

  5. Safety Analysis for Key Design Features of KALIMER-600 Design Concept

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Yong Bum; Kwon, Y. M.; Kim, E. K.; Suk, S. D.; Chang, W. P.; Jeong, H. Y.; Ha, K. S

    2007-02-15

    This report contains the safety analyses of the KALIMER-600 conceptual design which KAERI has been developing under the Long-term Nuclear R and D Program. The analyses have been performed reflecting the design developments during the second year of the 4th design phase in the program. The specific presentations are the key design features with the safety principles for achieving the safety objectives, the event categorization and safety criteria, and results on the safety analyses for the DBAs and ATWS events, the containment performance, and the channel blockages. The safety analyses for both the DBAs and ATWS events have been performed using SSC-K version 1.3., and the results have shown the fulfillment of the safety criteria for DBAs with conservative assumptions. The safety margins as well as the inherent safety also have been confirmed for the ATWS events. For the containment performance analysis, ORIGEN-2.1 and CONTAIN-LMR have been used. In results, the structural integrity has been acceptable and the evaluated exposure dose rate has been complied with 10 CFR 100 and PAG limits. The analysis results for flow blockages of 6-subchannels, 24-subchannels, and 54- subchannels with the MATRA-LMR-FB code, have assured the integrity of subassemblies.

  6. The key design features of the Indian advanced heavy water reactor

    International Nuclear Information System (INIS)

    Sinha, R.K.; Kakodkar, A.; Anand, A.K.; Venkat Raj, V.; Balakrishnan, K.

    1999-01-01

    The 235 MWe Indian Advanced Heavy Water Reactor (AHWR) is a vertical, pressure tube type, boiling light water cooled reactor. The three key specific features of design of the AHWR, having a large impact on its viability, safety and economics, relate to its reactor physics, coolant channel, and passive safety features. The reactor physics design is tuned for maximising use of thorium based fuel, and achieving a slightly negative void coefficient of reactivity. The fulfilment of these requirements has been possible through use of PuO 2 -ThO 2 MOX, and ThO 2 -U 233 O 2 MOX in different pins of the same fuel cluster, and use of a heterogeneous moderator consisting of pyrolytic carbon and heavy water in 80%-20% volume ratio. The coolant channels of AHWR are designed for easy replaceability of pressure tubes, during normal maintenance shutdowns. The removal of pressure tube along with bottom end-fitting, using rolled joint detachment technology, can be done in AHWR coolant channels without disturbing the top end-fitting, tail pipe and feeder connections, and all other appendages of the coolant channel. The AHWR incorporates several passive safety features. These include core heat removal through natural circulation, direct injection of Emergency Core Coolant System (ECCS) water in fuel, passive systems for containment cooling and isolation, and availability of a large inventory of borated water in overhead Gravity Driven Water Pool (GDWP) to facilitate sustenance of core decay heat removal, ECCS injection, and containment cooling for three days without invoking any active systems or operator action. Incorporation of these features has been done together with considerable design simplifications, and elimination of several reactor grade equipment. A rigorous evaluation of feasibility of AHWR design concept has been completed. The economy enhancing aspects of its key design features are expected to compensate for relative complexity of the thorium fuel cycle activities

  7. Preliminary safety analysis for key design features of KALIMER with breakeven core

    Energy Technology Data Exchange (ETDEWEB)

    Hahn, Do Hee; Kwon, Y. M.; Chang, W. P.; Suk, S. D.; Lee, Y. B.; Jeong, K. S

    2001-06-01

    KAERI is currently developing the conceptual design of a Liquid Metal Reactor, KALIMER (Korea Advanced Liquid MEtal Reactor) under the Long-term Nuclear R and D Program. KALIMER addresses key issues regarding future nuclear power plants such as plant safety, economics, proliferation, and waste. In this report, descriptions of safety design features and safety analyses results for selected ATWS accidents for the breakeven core KALIMER are presented. First, the basic approach to achieve the safety goal is introduced in Chapter 1, and the safety evaluation procedure for the KALIMER design is described in Chapter 2. It includes event selection, event categorization, description of design basis events, and beyond design basis events.In Chapter 3, results of inherent safety evaluations for the KALIMER conceptual design are presented. The KALIMER core and plant system are designed to assure benign performance during a selected set of events without either reactor control or protection system intervention. Safety analyses for the postulated anticipated transient without scram (ATWS) have been performed to investigate the KALIMER system response to the events. In Chapter 4, the design of the KALIMER containment dome and the results of its performance analyses are presented. The design of the existing containment and the KALIMER containment dome are compared in this chapter. Procedure of the containment performance analysis and the analysis results are described along with the accident scenario and source terms. Finally, a simple methodology is introduced to investigate the core energetics behavior during HCDA in Chapter 5. Sensitivity analyses have been performed for the KALIMER core behavior during super-prompt critical excursions, using mathematical formulations developed in the framework of the Modified Bethe-Tait method. Work energy potential was then calculated based on the isentropic fuel expansion model.

  8. Key features of MIR.1200 (AES-2006) design and current stage of Leningrad NPP-2 construction

    International Nuclear Information System (INIS)

    Ivkov, Igor

    2010-01-01

    MIR.1200/AES-2006 is an abbreviated name of the evolving NPP design developed on the basis of the VVER-1000 Russian design with gross operation life of 480 reactor-years. This design is being implemented in four Units of Leningrad NPP-2 (LNPP-2. The AES-91/99 was used as reference during development of the AES-2006 design for LNPP-2; this design was implemented in two Units of Tianwan NPP (China). The main technical features of the MIR.1200/AES-2006 design include a double containment, four trains of active safety systems (4x100%, 4x50%), and special engineering measures for BDBA management (core catcher, H2 PARs, PHRS) based mainly on passive principles. The containment is described in detail, the main features in comparison with the reference NPP are outlined, the design layout principles are highlighted, the safety system structure and parameters are described. Attention is paid to the BDBA management system, hydrogen removal system, core catcher, and PHRS-SG and C-PHRS. (P.A.)

  9. Key design features of a new smokefree law to help achieve the Smokefree Aotearoa.

    Science.gov (United States)

    Delany, Louise; Thomson, George; Wilson, Nick; Edwards, Richard

    2016-08-05

    To design new tobacco control legislation to achieve the New Zealand Government's 2025 smokefree goal. An original analysis of the legislative options for New Zealand tobacco control. 'Business as usual' is most unlikely to achieve smoking prevalence that is less than 5% by 2025. Key components of a new Act would ideally include plans and targets with teeth, a focus on the industry, a focus on the product, reduction of supply, and a whole-of-society approach to promote consistency in policy implementation through: i) a public duty on government agencies to act consistently with smokefree law; ii) a general duty on those associated with the tobacco/nicotine industry in relation to tobacco control objectives; and iii) a principle requiring international treaties to be interpreted consistently with tobacco control objectives. Strategies such as those identified in this Viewpoint should be explored further as part of urgently needed planning to achieve the New Zealand Government's goal for Smokefree Aotearoa by 2025.

  10. Key design features of multi-vacuum glazing for windows: A review

    Directory of Open Access Journals (Sweden)

    Ali Hassan

    2017-01-01

    Full Text Available The use of vacuum glazed windows is increasing due to their application in mod-ern building design. Among various types of vacuum glazed windows reported in literature, thermal transmittance of single glass sheet (conventional window i. e 6 W/m2k is reduced by 66 and 77% using air filled double glazed and air filled triple glazed windows, respectively. Using low emittance coatings thermal transmittance of double glazed windows is reduced by 53%, however it offsets the visibility by reduc-ing light transmittance by 5%. Stresses due to temperature/pressure gradients if not eliminated may lead to reduction in service life of vacuum glazed windows. Vacuum created between the glass sheets is used to reduce conductive heat transfer. Degrada-tion in the vacuum is caused by number of factors such as, permeation of gaseous molecules through glass sheets, leakage through sealing, thermal/optical desorption, and photo-fragmentation of organic species have been critically reviewed and future trends are outlined.

  11. Thermal enhancement cartridge heater modified tritium hydride bed development, Part 2 - Experimental validation of key conceptual design features

    Energy Technology Data Exchange (ETDEWEB)

    Heroux, K.J.; Morgan, G.A. [Savannah River Laboratory, Aiken, SC (United States)

    2015-03-15

    The Thermal Enhancement Cartridge Heater Modified (TECH Mod) tritium hydride bed is an interim replacement for the first generation (Gen1) process hydride beds currently in service in the Savannah River Site (SRS) Tritium Facilities. 3 new features are implemented in the TECH Mod hydride bed prototype: internal electric cartridge heaters, porous divider plates, and copper foam discs. These modifications will enhance bed performance and reduce costs by improving bed activation and installation processes, in-bed accountability measurements, end-of-life bed removal, and He-3 recovery. A full-scale hydride bed test station was constructed at the Savannah River National Laboratory (SRNL) in order to evaluate the performance of the prototype TECH Mod hydride bed. Controlled hydrogen (H{sub 2}) absorption/ desorption experiments were conducted to validate that the conceptual design changes have no adverse effects on the gas transfer kinetics or H{sub 2} storage/release properties compared to those of the Gen1 bed. Inert gas expansions before, during, and after H{sub 2} flow tests were used to monitor changes in gas transfer rates with repeated hydriding/de-hydriding of the hydride material. The gas flow rates significantly decreased after initial hydriding of the material; however, minimal changes were observed after repeated cycling. The data presented herein confirm that the TECH Mod hydride bed would be a suitable replacement for the Gen1 bed with the added enhancements expected from the advanced design features. (authors)

  12. Review of research in feature based design

    NARCIS (Netherlands)

    Salomons, O.W.; van Houten, Frederikus J.A.M.; Kals, H.J.J.

    1993-01-01

    Research in feature-based design is reviewed. Feature-based design is regarded as a key factor towards CAD/CAPP integration from a process planning point of view. From a design point of view, feature-based design offers possibilities for supporting the design process better than current CAD systems

  13. Iris recognition based on key image feature extraction.

    Science.gov (United States)

    Ren, X; Tian, Q; Zhang, J; Wu, S; Zeng, Y

    2008-01-01

    In iris recognition, feature extraction can be influenced by factors such as illumination and contrast, and thus the features extracted may be unreliable, which can cause a high rate of false results in iris pattern recognition. In order to obtain stable features, an algorithm was proposed in this paper to extract key features of a pattern from multiple images. The proposed algorithm built an iris feature template by extracting key features and performed iris identity enrolment. Simulation results showed that the selected key features have high recognition accuracy on the CASIA Iris Set, where both contrast and illumination variance exist.

  14. Features interior design offices

    OpenAIRE

    Novikov, A. S.; National Aviation University, Ukraine

    2014-01-01

    The article examines the laws and the formation of office space inthe current conditions and investigate the application of the latest technical tools aesthetics to improve the quality of design solutions.

  15. Key Features of the Manufacturing Vision Development Process

    DEFF Research Database (Denmark)

    Dukovska-Popovska, Iskra; Riis, Jens Ove; Boer, Harry

    2005-01-01

    of action research. The methodology recommends wide participation of people from different hierarchical and functional positions, who engage in a relatively short, playful and creative process and come up with a vision (concept) for the future manufacturing system in the company. Based on three case studies......This paper discusses the key features of the process of Manufacturing Vision Development, a process that enables companies to develop their future manufacturing concept. The basis for the process is a generic five-phase methodology (Riis and Johansen 2003) developed as a result of ten years...... of companies going through the initial phases of the methodology, this research identified the key features of the Manufacturing Vision Development process. The paper elaborates the key features by defining them, discussing how and when they can appear, and how they influence the process....

  16. Overview of KJRR design features

    International Nuclear Information System (INIS)

    Park, C.; Kim, Y.K.; Lee, B.C.; Ryu, J.S.; Kwon, Y.S.

    2015-01-01

    A new research reactor construction project (hereafter, “KJRR project”) is being conducted in order to secure the supply of key medical and industrial radioisotopes and to develop the core technologies of research reactors such as U-Mo fuel and a reactor bottom mounted control rod drive mechanism. The KJRR project aims to establish a RR with 15 MW and related utilization facilities for RI production and neutron transmutation doping (NTD) services, and the relevant research and development at Kijang-Gun, Busan City in Korea. A preliminary safety analysis report was submitted to the regulatory body for a construction permit in the end of 2014. The KJRR is under a detailed design and is expected to be put into operation in 2019. (author)

  17. Key features and progress of the KSTAR tokamak engineering

    International Nuclear Information System (INIS)

    Bak, J.S.; Choi, C.H.; Oh, Y.K.

    2003-01-01

    Substantial progress of the KSTAR tokamak engineering has been made on major tokamak structures, superconducting magnets, in-vessel components, diagnostic system, heating system, and power supplies. The engineering design has been elaborated to the extent necessary to allow a realistic assessment of its feasibility, performance, and cost. The prototype fabrication has been carried out to establish the reliable fabrication technologies and to confirm the validation of analyses employed for the KSTAR design. The completion of experimental building with beneficial occupancy for machine assembly was accomplished in Sep. 2002. The construction of special utility such as cryo-plant, de-ionized water-cooling system, and main power station will begin upon completion of building construction. The commissioning, construction, fabrication, and assembly of the whole facility will be going on by the end of 2005. This paper describes the main design features and engineering progress of the KSTAR tokamak, and elaborates the work currently underway. (author)

  18. Key clinical features to identify girls with CDKL5 mutations.

    Science.gov (United States)

    Bahi-Buisson, Nadia; Nectoux, Juliette; Rosas-Vargas, Haydeé; Milh, Mathieu; Boddaert, Nathalie; Girard, Benoit; Cances, Claude; Ville, Dorothée; Afenjar, Alexandra; Rio, Marlène; Héron, Delphine; N'guyen Morel, Marie Ange; Arzimanoglou, Alexis; Philippe, Christophe; Jonveaux, Philippe; Chelly, Jamel; Bienvenu, Thierry

    2008-10-01

    Mutations in the human X-linked cyclin-dependent kinase-like 5 (CDKL5) gene have been shown to cause infantile spasms as well as Rett syndrome (RTT)-like phenotype. To date, less than 25 different mutations have been reported. So far, there are still little data on the key clinical diagnosis criteria and on the natural history of CDKL5-associated encephalopathy. We screened the entire coding region of CDKL5 for mutations in 183 females with encephalopathy with early seizures by denaturing high liquid performance chromatography and direct sequencing, and we identified in 20 unrelated girls, 18 different mutations including 7 novel mutations. These mutations were identified in eight patients with encephalopathy with RTT-like features, five with infantile spasms and seven with encephalopathy with refractory epilepsy. Early epilepsy with normal interictal EEG and severe hypotonia are the key clinical features in identifying patients likely to have CDKL5 mutations. Our study also indicates that these patients clearly exhibit some RTT features such as deceleration of head growth, stereotypies and hand apraxia and that these RTT features become more evident in older and ambulatory patients. However, some RTT signs are clearly absent such as the so called RTT disease profile (period of nearly normal development followed by regression with loss of acquired fine finger skill in early childhood and characteristic intensive eye communication) and the characteristic evolution of the RTT electroencephalogram. Interestingly, in addition to the overall stereotypical symptomatology (age of onset and evolution of the disease) resulting from CDKL5 mutations, atypical forms of CDKL5-related conditions have also been observed. Our data suggest that phenotypic heterogeneity does not correlate with the nature or the position of the mutations or with the pattern of X-chromosome inactivation, but most probably with the functional transcriptional and/or translational consequences of CDKL5

  19. Identifying Key Features of Student Performance in Educational Video Games and Simulations through Cluster Analysis

    Science.gov (United States)

    Kerr, Deirdre; Chung, Gregory K. W. K.

    2012-01-01

    The assessment cycle of "evidence-centered design" (ECD) provides a framework for treating an educational video game or simulation as an assessment. One of the main steps in the assessment cycle of ECD is the identification of the key features of student performance. While this process is relatively simple for multiple choice tests, when…

  20. Cycling hypoxia: A key feature of the tumor microenvironment.

    Science.gov (United States)

    Michiels, Carine; Tellier, Céline; Feron, Olivier

    2016-08-01

    A compelling body of evidence indicates that most human solid tumors contain hypoxic areas. Hypoxia is the consequence not only of the chaotic proliferation of cancer cells that places them at distance from the nearest capillary but also of the abnormal structure of the new vasculature network resulting in transient blood flow. Hence two types of hypoxia are observed in tumors: chronic and cycling (intermittent) hypoxia. Most of the current work aims at understanding the role of chronic hypoxia in tumor growth, response to treatment and metastasis. Only recently, cycling hypoxia, with spatial and temporal fluctuations in oxygen levels, has emerged as another key feature of the tumor environment that triggers different responses in comparison to chronic hypoxia. Either type of hypoxia is associated with distinct effects not only in cancer cells but also in stromal cells. In particular, cycling hypoxia has been demonstrated to favor, to a higher extent than chronic hypoxia, angiogenesis, resistance to anti-cancer treatments, intratumoral inflammation and tumor metastasis. These review details these effects as well as the signaling pathway it triggers to switch on specific transcriptomic programs. Understanding the signaling pathways through which cycling hypoxia induces these processes that support the development of an aggressive cancer could convey to the emergence of promising new cancer treatments. Copyright © 2016 Elsevier B.V. All rights reserved.

  1. Key developments of the EP1000 design

    International Nuclear Information System (INIS)

    Noviello, L.

    1999-01-01

    In 1994, a group of European utilities initiated, together with Westinghouse and its industrial partner GENESI (an Italian consortium including ANSALDO and FIAT), a program designated EPP (European Passive Plant) to evaluate Westinghouse passive nuclear plant technology for application in Europe. The Phase I of the European Passive Plant program involved the evaluation of the Westinghouse 600 MWe AP600 and 1000 MWe Simplified Pressurized Water Reactor (SPWR) designs against the European Utility Requirements (EUR), and when necessary, the investigation of possible modifications to achieve compliance with the EUR. In Phase 1 of the program, which has been completed in 1996, the following major tasks were accomplished: The impacts of the European Utility Requirements (EUR) on the Westinghouse nuclear island design were evaluated. A 1000 MWe passive plant reference design (EP1000) was developed which conforms to the EUR and is expected to be licensable in Europe. With respect to the NSSS and containment, the EP1000 reference design closely follows those of the Westinghouse SPWR design, while the AP600 design has been taken as the basis for the design of the auxiliary systems. Extensive design and testing efforts have been made for the AP600 and SPWR during the respective multi-year programs. While the results of these programs have been and will continue to be utilised, at the maximum extent, to minimise the work to be performed on the EP1000 design, the compliance with EUR is a key design requirement for the EP1000 The ultimate objective of Phase 2 of the program is to develop design details and perform supporting analyses to produce a Safety Case Report (SCR) for submittal to European Safety Authorities. The first part of Phase 2, hereafter referred as Phase 2A, started at the beginning of 1997 and will be completed at the end of 1998. Scope of this phase of the program is to develop the design modifications of important systems and structures so to comply with the

  2. Engineering features of the INTOR conceptual design

    International Nuclear Information System (INIS)

    Shannon, T.E.

    1981-01-01

    The INTOR engineering design has been strongly influenced by considerations for assembly and maintenance. A maintenance philosophy was established at the outset of the conceptual design to insure that the tokamak configuration would be developed to accommodate maintenance requirements. The main features of the INTOR design are summarized in this paper with primary emphasis on the impact of maintenance considerations

  3. Residential neighbourhoods in Kathmandu: Key design guidelines

    Directory of Open Access Journals (Sweden)

    Bijaya K. Shrestha

    2013-01-01

    Full Text Available Residential neighbourhoods developed using various techniques in Kathmandu by both the public and private sectors have not only provided a poor urban setting and failed to address socio-cultural needs, but are also poor at building a community and creating links to the built environment, with the result that the planned areas lack a sense of place and the inhabitants lack a feeling of home. Although traditional neighbourhoods in the historic core area had many features of a good residential neighbourhood in the past, they are currently undergoing rapid destruction. The residents of these neighbourhoods have little awareness of these issues. The existing legal and institutional frameworks are inadequate and ineffective and cannot address these problems, and so the formulation of design guidelines, their strict implementation, and enhancement of socio-cultural events including social networking are recommended for future residential neighbourhood development.

  4. World Key Information Service System Designed For EPCOT Center

    Science.gov (United States)

    Kelsey, J. A.

    1984-03-01

    An advanced Bell Laboratories and Western Electric designed electronic information retrieval system utilizing the latest Information Age technologies, and a fiber optic transmission system is featured at the Walt Disney World Resort's newest theme park - The Experimental Prototype Community of Tomorrow (EPCOT Center). The project is an interactive audio, video and text information system that is deployed at key locations within the park. The touch sensitive terminals utilizing the ARIEL (Automatic Retrieval of Information Electronically) System is interconnected by a Western Electric designed and manufactured lightwave transmission system.

  5. Design features to reduce occupational exposure

    International Nuclear Information System (INIS)

    Adam, J.A.; DiSabatino, A.A. Jr.; Vanasse, R.E.

    1975-01-01

    Some of the design principles which are important considerations in the evolution of a nuclear power plant design to ensure that occupational radiation exposures can be minimized are discussed. Emphasis is placed on the design features affecting the basic layout and equipment locations within the plant. Examples are provided showing how these design objectives are realized in the Stone and Webster Reference Nuclear Power Plant Design, with particular emphasis on the Annulus Building portion of the reference plant. Design features which are useful in reducing occupational exposure during normal operation are discussed initially, followed by those that chiefly affect exposures during maintenance activity. Finally, those provisions in the design which assist in preventing the spread of radioactive contamination are presented

  6. Key Clinical Features to Identify Girls with "CDKL5" Mutations

    Science.gov (United States)

    Bahi-Buisson, Nadia; Nectoux, Juliette; Rosas-Vargas, Haydee; Milh, Mathieu; Boddaert, Nathalie; Girard, Benoit; Cances, Claude; Ville, Dorothee; Afenjar, Alexandra; Rio, Marlene; Heron, Delphine; Morel, Marie Ange N'Guyen; Arzimanoglou, Alexis; Philippe, Christophe; Jonveaux, Philippe; Chelly, Jamel; Bienvenu, Thierry

    2008-01-01

    Mutations in the human X-linked cyclin-dependent kinase-like 5 ("CDKL5") gene have been shown to cause infantile spasms as well as Rett syndrome (RTT)-like phenotype. To date, less than 25 different mutations have been reported. So far, there are still little data on the key clinical diagnosis criteria and on the natural history of…

  7. Fabled IBM Tank nears launch without key features

    CERN Multimedia

    2003-01-01

    "IBM is preparing to roll out the TotalStorage SAN File System, the ballyhooed, renamed, much delayed Storage Tank the company's been working on for ages, although it now appears some of its key capabilities won't appear until next year in a later version" (1 page).

  8. Designing organizational structures: Key thoughts for development.

    Science.gov (United States)

    Killingsworth, Patricia; Eschenbacher, Lynn

    2018-04-01

    Current strategies and concepts to consider in developing a system-level organizational structure for the pharmacy enterprise are discussed. There are many different ways to design an organizational structure for the pharmacy enterprise within a health system. The size of the organization, the number of states in which it operates, and the geographic spread and complexity of the pharmacy business lines should be among the key considerations in determining the optimal organizational and decision-making structures for the pharmacy enterprise. The structure needs to support incorporation of the pharmacy leadership (both system-level executives and local leaders) into all strategic planning and discussions at the hospital and health-system levels so that they can directly represent the pharmacy enterprise instead of relying on others to develop strategy on their behalf. It is important that leaders of all aspects of the pharmacy enterprise report through the system's top pharmacy executive, who should be a pharmacist and have a title consistent with those of other leaders reporting at the same organizational level (e.g., chief pharmacy officer). Pharmacy leaders need to be well positioned within an organization to advocate for the pharmacy enterprise and use all resources to the best of their ability. As the scope and complexity of pharmacy services grow, it is critical to ensure that leadership of the pharmacy enterprise is unified under a single pharmacy executive team. Copyright © 2018 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

  9. The idiopathic interstitial pneumonias: understanding key radiological features

    Energy Technology Data Exchange (ETDEWEB)

    Dixon, S. [Department of Radiology, Churchill Hospital, Old Road, Oxford OX3 7LJ (United Kingdom); Benamore, R., E-mail: Rachel.Benamore@orh.nhs.u [Department of Radiology, Churchill Hospital, Old Road, Oxford OX3 7LJ (United Kingdom)

    2010-10-15

    Many radiologists find it challenging to distinguish between the different interstitial idiopathic pneumonias (IIPs). The British Thoracic Society guidelines on interstitial lung disease (2008) recommend the formation of multidisciplinary meetings, with diagnoses made by combined radiological, pathological, and clinical findings. This review focuses on understanding typical and atypical radiological features on high-resolution computed tomography between the different IIPs, to help the radiologist determine when a confident diagnosis can be made and how to deal with uncertainty.

  10. The idiopathic interstitial pneumonias: understanding key radiological features

    International Nuclear Information System (INIS)

    Dixon, S.; Benamore, R.

    2010-01-01

    Many radiologists find it challenging to distinguish between the different interstitial idiopathic pneumonias (IIPs). The British Thoracic Society guidelines on interstitial lung disease (2008) recommend the formation of multidisciplinary meetings, with diagnoses made by combined radiological, pathological, and clinical findings. This review focuses on understanding typical and atypical radiological features on high-resolution computed tomography between the different IIPs, to help the radiologist determine when a confident diagnosis can be made and how to deal with uncertainty.

  11. Main engineering features driving design concept and engineering design constraints

    International Nuclear Information System (INIS)

    Saito, Ryusei; Kobayashi, Takeshi; Yamada, Masao

    1987-09-01

    Major engineering design philosophies are described, which are essential bases for an engineering design and may have significant impacts on a reactor design concept. Those design philosophies are classified into two groups, engineering design drivers and engineering design constraints. The design drivers are featured by the fact that a designer is free to choose and the choice may be guided by his opinion, such as coil system, a mechanical configuration, a tritium breeding scenario, etc.. The design constraints may follow a natural law or engineering limit, such as material strength, coil current density, and so on. (author)

  12. Main physics features driving design concept and physics design constraints

    International Nuclear Information System (INIS)

    Fujisawa, Noboru; Sugihara, Masayoshi; Yamamoto, Shin

    1987-07-01

    Major physics design philosophies are described, which are essential bases for a plasma design and may have significant impacts on a reactor design concept. Those design philosophies are classified into two groups, physics design drivers and physics design constraints. The design drivers are featured by the fact that a designer is free to choose and the choice may be guided by his opinion, such as ignition, a pulse length, an operation scenario, etc.. The design constraints may follow a physical law, such as plasma confinement, β-limit, density limit, and so on. (author)

  13. Safety design features of the IRIS

    International Nuclear Information System (INIS)

    2009-01-01

    The International Reactor Innovative and Secure (IRIS) is an advanced, integral, light water cooled reactor of medium generating capacity (335 MW(e)), that features an integral reactor vessel containing all the reactor primary system components, including steam generators, coolant pumps, pressurizer and heaters, and control rod drive mechanisms; in addition to the typical core, internals, control rods and neutron reflector. This integral configuration allows for the use of a small, high design pressure, spherical steel containment which results in a significant reduction in the size of the nuclear island. Other IRIS innovations include a simplified passive safety system concept and equipment features that derive from the 'safety-by-design' philosophy. This design approach allows for elimination of certain accident initiators at the design stage, or when outright elimination is not possible, decreases accident consequences and/or their probability of occurrence. Major design characteristics of the IRIS are given. As part of the IRIS pre-application licensing review by the U.S. Nuclear Regulatory Commission (NRC), the IRIS design team has developed a test plan that will provide the necessary data for safety analysis computer model verification, as well as for verifying the manufacturing feasibility, operability, and durability of new component designs

  14. Key variables of organisation design in servitization

    DEFF Research Database (Denmark)

    Kreye, Melanie; Jensen, Per Langaa

    2014-01-01

    Manufacturing companies offering additional service with their products need to change their organisation design to accommodate for the service business. Using the star model, this paper investigates organisation design in terms of strategy, structure, processes, rewards and people as a response ...

  15. Mechanical Design Features of PGSFR NSSS

    International Nuclear Information System (INIS)

    Park, Chang-Gyu; Koo, Gyeong-Hoi; Cho, Jae-Hun; Kim, Sung-Kyun

    2016-01-01

    The NSSS(Nuclear Steam Supply System) is composed of PHTS(Primary Heat Transport System), IHTS (Intermediate Heat Transport System), and SGS(Steam Generation System). And, DHRS(Decay Heat Removal System) adopts both the active and passive systems for diversity. The structures including components and piping should be designed to ensure the structural integrity for their design life against mechanical and operational loads. In this study, the mechanical design features for the structures and components that make up PGSFR NSSS are described. The mechanical design features of structures and components for a PGSFR NSSS are described. The structures are being designed to maintain the structural integrity for their design lifetime by considering the high temperature operating condition. The decay heat removal system(DHRS) removes all reactor decay heat in two ways; active type(ADHRS) and passive type(PDHRS). ADHRS consists of DHX, blower, FHX, circulation pump, and expansion tank. But PDHRS consists of DHX, AHX, and expansion tank. FHX is a finned-tube-type sodium-to-air heat exchanger whereas AHX is a helical-type sodium-to-air heat exchanger

  16. Mechanical Design Features of PGSFR NSSS

    Energy Technology Data Exchange (ETDEWEB)

    Park, Chang-Gyu; Koo, Gyeong-Hoi; Cho, Jae-Hun; Kim, Sung-Kyun [KAERI, Daejeon (Korea, Republic of)

    2016-05-15

    The NSSS(Nuclear Steam Supply System) is composed of PHTS(Primary Heat Transport System), IHTS (Intermediate Heat Transport System), and SGS(Steam Generation System). And, DHRS(Decay Heat Removal System) adopts both the active and passive systems for diversity. The structures including components and piping should be designed to ensure the structural integrity for their design life against mechanical and operational loads. In this study, the mechanical design features for the structures and components that make up PGSFR NSSS are described. The mechanical design features of structures and components for a PGSFR NSSS are described. The structures are being designed to maintain the structural integrity for their design lifetime by considering the high temperature operating condition. The decay heat removal system(DHRS) removes all reactor decay heat in two ways; active type(ADHRS) and passive type(PDHRS). ADHRS consists of DHX, blower, FHX, circulation pump, and expansion tank. But PDHRS consists of DHX, AHX, and expansion tank. FHX is a finned-tube-type sodium-to-air heat exchanger whereas AHX is a helical-type sodium-to-air heat exchanger.

  17. SUCCESS KEY IN DESIGNING A NEW PRODUCT

    OpenAIRE

    Liliana LUCA; Constanţa RĂDULESCU

    2017-01-01

    In this paper we use a quality management instrument called a tree diagram, based on undigital data, in order to show what the solutions are in order to solve an analyzed problem. The problem proposed to be analyzed is: identifying specific objects and corresponding measures to successfully design a new product. The proposed solutions are grouped into three specific objectives: Top management commitment; Beneficiary need analysis; Designing process quality. The tree diagram for th...

  18. HANARO cooling features: design and experience

    International Nuclear Information System (INIS)

    Park, Cheol; Chae, Hee-Taek; Han, Gee-Yang; Jun, Byung-Jin; Ahn, Guk-Hoon

    1999-01-01

    In order to achieve the safe core cooling during normal operation and upset conditions, HANARO adopted an upward forced convection cooling system with dual containment arrangements instead of the forced downward flow system popularly used in the majority of forced convection cooling research reactors. This kind of upward flow system was selected by comparing the relative merits of upward and downward flow systems from various points of view such as safety, performance, maintenance. However, several operational matters which were not regarded as serious at design come out during operation. In this paper are presented the design and operational experiences on the unique cooling features of HANARO. (author)

  19. New features in the design code TLIE

    International Nuclear Information System (INIS)

    van Zeijts, J.

    1993-01-01

    We present features recently installed in the arbitrary-order accelerator design code TLIE. The code uses the MAD input language, and implements programmable extensions modeled after the C language that make it a powerful tool in a wide range of applications: from basic beamline design to high precision-high order design and even control room applications. The basic quantities important in accelerator design are easily accessible from inside the control language. Entities like parameters in elements (strength, current), transfer maps (either in Taylor series or in Lie algebraic form), lines, and beams (either as sets of particles or as distributions) are among the type of variables available. These variables can be set, used as arguments in subroutines, or just typed out. The code is easily extensible with new datatypes

  20. Key issues in european reactor seismic design

    International Nuclear Information System (INIS)

    Cicognani, G.; Martelli, A.

    1984-01-01

    The paper focuses on the main problems which have arisen in FBR design in Europe due to seismic conditions. Its first part, derived from the final report of a CEC-Belgonucleaire study contract, clarifies how ''real'' is the seismic problem for each site. Then, the second and main part deals with the studies carried out in the european countries on the relevant subjects, typical of FBRs or related to specific needs of single FBRs: these studies, for which contributions were provided by ENEA, CEA, NNC and INTERATOM, concern mainly the numerical and experimental analysis of the core, the reactor vessel, the shut-down system and the reactor building of FBRs under construction or in advanced design phase. Attention is also paid to the studies started for future purposes, the feed-backs on the design due to seismic conditions, and the instructions for future reactors

  1. Key Design Properties for Shipping Information Pipeline

    DEFF Research Database (Denmark)

    Jensen, Thomas; Tan, Yao-Hua

    2015-01-01

    on paper, e-mail, phone and text message, and far too costly. This paper explores the design properties for a shared information infrastructure to exchange information between all parties in the supply chain, commercial parties as well as authorities, which is called a Shipping Information Pipeline...

  2. Design Features of Modern Mechanical Ventilators.

    Science.gov (United States)

    MacIntyre, Neil

    2016-12-01

    A positive-pressure breath ideally should provide a V T that is adequate for gas exchange and appropriate muscle unloading while minimizing any risk for injury or discomfort. The latest generation of ventilators uses sophisticated feedback systems to sculpt positive-pressure breaths according to patient effort and respiratory system mechanics. Currently, however, these new control strategies are not totally closed-loop systems. This is because the automatic input variables remain limited, some clinician settings are still required, and the specific features of the perfect breath design still are not entirely clear. Despite these limitations, there are some rationale for many of these newer feedback features. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. Design alternatives, components key to optimum flares

    International Nuclear Information System (INIS)

    Cunha-Leite, O.

    1992-01-01

    A properly designed flare works as an emissions control system with greater than 98% combustion efficiency. The appropriate use of steam, natural gas, and air-assisted flare tips can result in smokeless combustion. Ground flare, otherwise the elevated flare is commonly chosen because it handles larger flow releases more economically. Flaring has become more complicated than just lighting up waste gas. Companies are increasingly concerned about efficiency. In addition, U.S. Occupational Safety and Health Administration (OSHA) and U.S. Environmental Protection Agency (EPA) have become more active, resulting in tighter regulations on both safety and emissions control. These regulations have resulted in higher levels of concern and involvement in safety and emissions matters, not to mention smoke, noise, glare, and odor. This first to two articles on flare design and components looks at elevated flares, flare tips, incinerator-type flares, flare pilots, and gas seals. Part 2 will examine knockout drums, liquid-seal drums, ignition systems, ground flares, vapor recovery systems, and flare noise

  4. Design features of APWR in Japan

    International Nuclear Information System (INIS)

    Yamaguchi, H.; Aeba, Y.; Weiss, E.H.

    1999-01-01

    Development of the Advanced Pressurized Water Reactor (APWR) was executed in the Improvement and Standardization Program which was organized by the Ministry of International Trade and Industry, Japanese utilities (Hokkaido, Kansai, Shikoku, Kyushu Electric Power Companies and the Japan Atomic Power Company) and manufacturers (Mitsubishi Heavy Industries and Westinghouse Electric). Improvements in terms of safety, reliability, operability, maintainability and economy have been incorporated based on comprehensive evaluations of both the advanced technologies available today, and the experience associated with construction and operation of current PWR plants. The main design improvement features applied in APWR include a core design that contributes to effective use of uranium resource, safety enhancement in the engineered safeguard system, and reliability enhancement in the reactor internal structures. This paper briefly describes the main features of the APWR design focusing on the following two items: the radial reflector, which enhances reliability of the reactor internal structures as well as neutron economy in the core region; and an advanced accumulator, which enhances Emergency Core Cooling System (ECCS) reliability and contributes to system simplification due to passive low pressure injection function. (author)

  5. Innovative features and fuel design approach in the iris reactor

    International Nuclear Information System (INIS)

    Petrovic, B.; Carelli, M.; Greenspan, E.; Matsumoto, H.; Padovani, E.; Ganda, F.

    2002-01-01

    The International Reactor Innovative and Secure (IRIS) is being developed by an international consortium of industry, laboratory, university and utility establishments, led by Westinghouse. The IRIS design addresses key requirements associated with advanced reactors, including improved safety, enhanced proliferation resistance, competitive electricity production cost, and improved waste management. IRIS is a modular, small/medium size (335 MWe) PWR with an integral vessel configuration. The objective has been to base its design on proven LWR technology, so that no new technology development is needed and near-term deployment is possible, yet at the same time to introduce innovative features making it attractive when compared to present PWRs. These opposing requirements resulted in an evolutionary approach to fuel and core design, balancing new features against the need to avoid extensive testing and demonstration programmes. (author)

  6. The Impact Of Website Design Features On Behavioral Intentions

    Directory of Open Access Journals (Sweden)

    Chun-Chin Chiu

    2015-08-01

    Full Text Available The design of a website interface plays an important role in online purchasing and customers are more likely to visit and buy from better-designed websites. However previous studies have not provided consistent information about the features a website should provide. Based on Hausman and Siekpes 2009 comprehensive model this study aims to empirically verify whether the model can be applied in e-service markets to predict and explain website users behavioral intentions trade intentions and revisit intentions. Based on the data from a survey of 303 Internet users the results indicate that computer factors and human factors the key website design features are significantly related to website users experiences perceived usefulness perceived entertainment value and perceived informativeness in turn significantly affect the intermediary outcomes of attitude toward the site and ultimately influence users behavioral intentions.

  7. Design Feature 7: Continuous Preclosure Ventilation

    International Nuclear Information System (INIS)

    A.T. Watkins

    1999-01-01

    This design feature (DF) is intended to evaluate the effects of continuous ventilation in the emplacement drifts during preclosure and how the effects, if any, compare to the Viability Assessment (VA) reference design for postclosure long term performance. This DF will be evaluated against a set of criteria provided by the License Application Design Selection (LADS) group. The VA reference design included a continuous ventilation airflow quantity of 0.1 m 3 /s in the emplacement drifts in the design of the repository subsurface facilities. The effects of this continuous ventilation during the preclosure was considered to have a negligible effect on postclosure performance and therefore is not included during postclosure in the assessment of the long term performance. This DF discusses the effects of continuous ventilation on the emplacement drift environment and surrounding rock conditions during preclosure for three increased airflow quantities. The three cases of continuous ventilation systems are: System A, 1.0 m 3 /s (Section 8), System B, 5.0 m 3 /s (Section 9), and System C, 10.0 m 3 /s (Section 10) in each emplacement drift split. An emplacement drift split is half total length of emplacement drift going from the east or west main to the exhaust main. The difference in each system is the quantity of airflow in the emplacement drifts

  8. Key-Feature-Probleme zum Prüfen von prozeduralem Wissen: Ein Praxisleitfaden [Key Feature Problems for the assessment of procedural knowledge: a practical guide

    Directory of Open Access Journals (Sweden)

    Kopp, Veronika

    2006-08-01

    Full Text Available [english] After assigning the different examination formats to the diverse terms of Miller's pyramide of knowledge, this paper provides a short presentation of the key feature approach by giving the definition and an example for clarification. Afterwards, a practical guide to writing key feature problems is given consisting of the following steps: define the domain, choose a clinical situation, define the key features, develop a test case scenario, write questions, select a preferred response format, define the scoring key, and validation. Finally, we present the evaluation results of this practical guide. In sum, the participants were very pleased with it. The differences between the estimations of their knowledge before and after the workshop concerning key features were significant. The key feature approach is an innovative tool for assessing clinical decision-making skills, also for electronical examinations. Substituting the write-in format for the long-menu format allows an automatic data analysis. [german] Im vorliegenden Beitrag wird - nach der Zuordnung unterschiedlicher Prüfungsformen zu den verschiedenen Wissensarten der Wissenspyramide von Miller - der Key-Feature (KF Ansatz vorgestellt. Nachdem anhand der Definition und einem Beispiel erklärt wurde, was ein KF ist, wird im Anschluss eine Anleitung für die Erstellung eines KF-Problems gegeben. Diese besteht aus folgenden Schritten: Definition des Kontextes, Wahl der klinischen Situation, Identifikation der KFs des klinischen Problems, Schreiben des klinischen Szenarios (Fallvignette, Schreiben der einzelnen KF-Fragen, Auswahl des Antwortformates, Bewertungsverfahren und Inhaltsvalidierung. Am Ende werden die Ergebnisse einer Evaluation dieser Anleitung, die im Rahmen eines KF-Workshops gewonnen wurden, präsentiert. Die Teilnehmer waren mit dieser Workshopeinheit sehr zufrieden und gaben an, sehr viel gelernt zu haben. Die subjektive Einschätzung ihres Wissensstands vor und nach

  9. Designing key-dependent chaotic S-box with larger key space

    International Nuclear Information System (INIS)

    Yin Ruming; Yuan Jian; Wang Jian; Shan Xiuming; Wang Xiqin

    2009-01-01

    The construction of cryptographically strong substitution boxes (S-boxes) is an important concern in designing secure cryptosystems. The key-dependent S-boxes designed using chaotic maps have received increasing attention in recent years. However, the key space of such S-boxes does not seem to be sufficiently large due to the limited parameter range of discretized chaotic maps. In this paper, we propose a new key-dependent S-box based on the iteration of continuous chaotic maps. We explore the continuous-valued state space of chaotic systems, and devise the discrete mapping between the input and the output of the S-box. A key-dependent S-box is constructed with the logistic map in this paper. We show that its key space could be much larger than the current key-dependent chaotic S-boxes.

  10. Important conventional island design features: generators

    International Nuclear Information System (INIS)

    Fritsch, Th.

    1985-01-01

    To-day, maximum reactor capacity is setting a provisional limit to the MW race. The latest nuclear generators in manufacturing are rated 1530 MW - 1710 MVA and are doubtless the most powerful ones in the world. The target to be aimed at in designing large turbogenerators may be defined by the following points: 1) meeting the rated load conditions without overpassing maximum admissible temperatures in any part of the machine; 2) keeping losses as small as possible; 3) keeping overall size small enough to allow rail transportation from the works to the site; 4) choosing well experienced solutions in order to set a highly reliable machine with maximum maintenance. In this report the main features of nuclear generators in the 1000-2000 MVA range are described. (Auth.)

  11. Safety features of the MAPLE-X10 reactor design

    International Nuclear Information System (INIS)

    Lee, A.G.; Bishop, W.E.; Heeds, W.

    1990-09-01

    The MAPLE-X10 reactor is a D 2 0-reflected, H 2 0-cooled and -moderated pool-type reactor under construction at the Chalk River Nuclear Laboratories. This 10-MW reactor will produce key medical and industrial radio-isotopes such as 99 Mo, 125 I, and 192 Ir. As the prototype for the MAPLE research reactor concept, the reactor incorporates diverse safety features both inherent in the design and in the added engineered systems. The safety requirements are analogous to those of the Canadian CANDU power reactor since standards for the licensing of new research reactors have not been developed yet by the licensing authority in Canada

  12. Safety features of the MAPLE-X10 reactor design

    International Nuclear Information System (INIS)

    Lee, A.G.; Bishop, W.E.; Heeds, W.

    1990-01-01

    This paper reports on the MAPLE-X10 reactor D 2 O-reflected, H 2 O-cooled and -moderated pool- type reactor, under construction at the Chalk River Nuclear Laboratories. This 10-MW will produce key medical and industrial radioisotopes such as 99 Mo, 125 I, and 192 Ir. The prototype for the MAPLE research reactor concept, the reactor incorporates diverse safety features both inherent in the design and in the added engineered systems. The safety requirements are analogous to those of the Canadian CANDU power reactor as standards for the licensing of new research reactors have not been developed by the licensing authority in Canada

  13. Richards Barrier LA Reference Design Feature Evaluation

    International Nuclear Information System (INIS)

    N.E. Kramer

    1999-01-01

    The Richards Barrier is one of the design features of the repository to be considered for the License Application (LA), Richards was a soil scientist who first described the diversion of moisture between two materials with different hydrologic properties. In this report, a Richards Barrier is a special type of backfill with a fine-grained material (such as sand) overlaying a coarse-grained material (such as gravel). Water that enters an emplacement drift will first encounter the fine-grained material and be transported around the coarse-grained material covering the waste package, thus protecting the waste package from contact with most of the groundwater. The objective of this report is to discuss the benefits and liabilities to the repository by the inclusion of a Richards Barrier type backfill in emplacement drifts. The Richards Barrier can act as a barrier to water flow, can reduce the waste package material dissolution rate, limit mobilization of the radionuclides, and can provide structural protection for the waste package. The scope of this report is to: (1) Analyze the behavior of barrier materials following the intrusion of groundwater for influxes of 1 to 300 mm per year. The report will demonstrate diversion of groundwater intrusions into the barrier over an extended time period when seismic activity and consolidation may cause the potential for liquefaction and settlement of the Richards Barrier. (2) Review the thermal effects of the Richards Barrier on material behavior. (3) Analyze the effect of rockfall on the performance of the Richards Barrier and the depth of the barrier required to protect waste packages under the barrier. (4) Review radiological and heating conditions on placement of multiple layers of the barrier. Subsurface Nuclear Safety personnel will perform calculations to determine the radiation reduction-time relationship and shielding capacity of the barrier. (5) Evaluate the effects of ventilation on cooling of emplacement drifts and

  14. Recent Development of the Two-Stroke Engine. II - Design Features. 2; Design Features

    Science.gov (United States)

    Zeman, J.

    1945-01-01

    Completing the first paper dealing with charging methods and arrangements, the present paper discusses the design forms of two-stroke engines. Features which largely influence piston running are: (a) The shape and surface condition of the sliding parts. (b) The cylinder and piston materials. (c) Heat conditions in the piston, and lubrication. There is little essential difference between four-stroke and two-stroke engines with ordinary pistons. In large engines, for example, are always found separately cast or welded frames in which the stresses are taken up by tie rods. Twin piston and timing piston engines often differ from this design. Examples can be found in many engines of German or foreign make. Their methods of operation will be dealt with in the third part of the present paper, which also includes the bibliography. The development of two-stroke engine design is, of course, mainly concerned with such features as are inherently difficult to master; that is, the piston barrel and the design of the gudgeon pin bearing. Designers of four-stroke engines now-a-days experience approximately the same difficulties, since heat stresses have increased to the point of influencing conditions in the piston barrel. Features which notably affect this are: (a) The material. (b) Prevailing heat conditions.

  15. Design Features of the SMART Water Chemistry

    International Nuclear Information System (INIS)

    Byung Seon Choi; Seong Hoon Kim; Juhyeon Yoon; Doo Jeong Lee; Yoon Yeong Bae; Sung Kyun Zee

    2004-01-01

    The design features for the primary water chemistry for the SMART are introduced from the viewpoint of the system characteristics and the chemical design concept. The most essential differences in water chemistry between the commercially operating PWRs and SMART are characterized by the presence of boron in the water and the operating mode of the purification system. SMART is a soluble boron free reactor, and the ammonia is used as a pH reagent. The material for SMART steam generator is also different from the standard material of the commercially operating PWRs: titanium alloy for the steam generator tubes. In SMART hydrogen gas which suppresses a generation of oxidizing species by the radiolysis processes in the reactors is not added to the primary coolant, but is normally generated from the radiolysis of the ammonia as the coolant passes through the core. Ammonia is added once per shift because SMART reactor has no letdown and charging system during power operation. Because of these competing processes, the concentrations of hydrogen, nitrogen and ammonia in the primary coolant are in equilibrium, which depend on the decomposition and/or combination rate of the ammonia. The level of permissible oxygen concentration in the primary coolant can be ensured by both suppression of the water radiolysis through maintaining a high enough hydrogen concentration in the primary coolant and by a restriction of the oxygen ingress into the primary coolant with the makeup water. The ammonia chemistry in SMART reactor eliminates the need for hydrogen injection for the control of the dissolved oxygen in the primary coolant because of spontaneous generation of hydrogen and nitrogen produced by the reaction of the ammonia decomposition. (authors)

  16. Communicating Emotion through Haptic Design: A Study Using Physical Keys

    DEFF Research Database (Denmark)

    Kjellerup, Marie Kjær; Larsen, Anne Cathrine; Maier, Anja

    2014-01-01

    This paper explores how designers may communicate with the users of their products through haptic design. More specifically, how tactile properties of materials evoke emotions such as satisfaction, joy, or disgust. A research through design approach has been followed; mood- and material boards...... and prototypes of four ‘haptically enhanced’ (physical) keys were created. Types of keys selected include home, bicycle, hobby, and basement. An experiment with ten participants was conducted, using word association and a software to elicit product emotions (PrEmo). Results show a mapping between the designer...

  17. Salient Key Features of Actual English Instructional Practices in Saudi Arabia

    Science.gov (United States)

    Al-Seghayer, Khalid

    2015-01-01

    This is a comprehensive review of the salient key features of the actual English instructional practices in Saudi Arabia. The goal of this work is to gain insights into the practices and pedagogic approaches to English as a foreign language (EFL) teaching currently employed in this country. In particular, we identify the following central features…

  18. Toward Designing a Quantum Key Distribution Network Simulation Model

    OpenAIRE

    Miralem Mehic; Peppino Fazio; Miroslav Voznak; Erik Chromy

    2016-01-01

    As research in quantum key distribution network technologies grows larger and more complex, the need for highly accurate and scalable simulation technologies becomes important to assess the practical feasibility and foresee difficulties in the practical implementation of theoretical achievements. In this paper, we described the design of simplified simulation environment of the quantum key distribution network with multiple links and nodes. In such simulation environment, we analyzed several ...

  19. Identifying Key Features of Effective Active Learning: The Effects of Writing and Peer Discussion

    Science.gov (United States)

    Pangle, Wiline M.; Wyatt, Kevin H.; Powell, Karli N.; Sherwood, Rachel E.

    2014-01-01

    We investigated some of the key features of effective active learning by comparing the outcomes of three different methods of implementing active-learning exercises in a majors introductory biology course. Students completed activities in one of three treatments: discussion, writing, and discussion + writing. Treatments were rotated weekly between three sections taught by three different instructors in a full factorial design. The data set was analyzed by generalized linear mixed-effect models with three independent variables: student aptitude, treatment, and instructor, and three dependent (assessment) variables: change in score on pre- and postactivity clicker questions, and coding scores on in-class writing and exam essays. All independent variables had significant effects on student performance for at least one of the dependent variables. Students with higher aptitude scored higher on all assessments. Student scores were higher on exam essay questions when the activity was implemented with a writing component compared with peer discussion only. There was a significant effect of instructor, with instructors showing different degrees of effectiveness with active-learning techniques. We suggest that individual writing should be implemented as part of active learning whenever possible and that instructors may need training and practice to become effective with active learning. PMID:25185230

  20. License Application Design Selection Feature Report: Waste Package Self Shielding Design Feature 13

    International Nuclear Information System (INIS)

    Tang, J.S.

    2000-01-01

    In the Viability Assessment (VA) reference design, handling of waste packages (WPs) in the emplacement drifts is performed remotely, and human access to the drifts is precluded when WPs are present. This report will investigate the feasibility of using a self-shielded WP design to reduce the radiation levels in the emplacement drifts to a point that, when coupled with ventilation, will create an acceptable environment for human access. This provides the benefit of allowing human entry to emplacement drifts to perform maintenance on ground support and instrumentation, and carry out performance confirmation activities. More direct human control of WP handling and emplacement operations would also be possible. However, these potential benefits must be weighed against the cost of implementation, and potential impacts on pre- and post-closure performance of the repository and WPs. The first section of this report will provide background information on previous investigations of the self-shielded WP design feature, summarize the objective and scope of this document, and provide quality assurance and software information. A shielding performance and cost study that includes several candidate shield materials will then be performed in the subsequent section to allow selection of two self-shielded WP design options for further evaluation. Finally, the remaining sections will evaluate the impacts of the two WP self-shielding options on the repository design, operations, safety, cost, and long-term performance of the WPs with respect to the VA reference design

  1. Seaworthy Quantum Key Distribution Design and Validation (SEAKEY)

    Science.gov (United States)

    2015-11-12

    polarization control and the CV state and the LO state are separated at a polarizing beam splitter . The CV state is delayed relative to the LO state, and... splitter or loss imperfections. We have identified a number of risks associated with implementing this design . The two most critical risks are: • The...Contractor Address: 10 Moulton Street, Cambridge, MA 02138 Title of the Project: Seaworthy Quantum Key Distribution Design and Validation (SEAKEY

  2. Design features impacting mobile phone upgrading frequency

    NARCIS (Netherlands)

    Saaksjarvi, M.C.; Hellen, K.; Tuunanen, T.

    2014-01-01

    This study examines the impact of design on customer upgrading frequency, and differentiates between functional and aesthetic aspects of design. For the empirical study, we conducted an intercept survey in Beijing and Shanghai with Chinese consumers (n=170) in a retail mall setting. The survey’s

  3. Key Features of Political Advertising as an Independent Type of Advertising Communication

    Directory of Open Access Journals (Sweden)

    Svetlana Anatolyevna Chubay

    2015-09-01

    Full Text Available To obtain the most complete understanding of the features of political advertising, the author characterizes its specific features allocated by modern researchers. The problem of defining the notion of political advertising is studied in detail. The analysis of definitions available in professional literature has allowed the author to identify a number of key features that characterize political advertising as an independent type of promotional activity. These features include belonging to the forms of mass communication, implemented through different communication channels; the presence of characteristics typical of any advertising as a form of mass communication (strategies and concepts promoting the program, ideas; an integrated approach to the selection of communication channels, means and the methods of informing the addressers that focus on the audience; the formation of psychological attitude to voting; the image nature; the manipulative potential. It is shown that the influence is the primary function of political advertising – it determines the key characteristics common to this type of advertising. Political advertising, reflecting the essence of the political platform of certain political forces, setting up voters for their support, forming and introducing into the mass consciousness a definite idea of the character of these political forces, creates the desired psychological attitude to the voting. The analysis of definitions available in professional literature has allowed the author to formulate an operational definition of political advertising, which allowed to include the features that distinguish political advertising from other forms of political communication such as political PR which is traditionally mixed with political advertising.

  4. Key Features of Electric Vehicle Diffusion and Its Impact on the Korean Power Market

    Directory of Open Access Journals (Sweden)

    Dongnyok Shim

    2018-06-01

    Full Text Available The market share of electric vehicles is growing and the interest in these vehicles is rapidly increasing in industrialized countries. In the light of these circumstances, this study provides an integrated policy-making package, which includes key features for electric vehicle diffusion and its impact on the Korean power market. This research is based on a quantitative analysis with the following steps: (1 it analyzes drivers’ preferences for electric or traditional internal combustion engine (ICE vehicles with respect to key automobile attributes and these key attributes indicate what policy makers should focus on; (2 it forecasts the achievable level of market share of electric vehicles in relation to improvements in their key attributes; and (3 it evaluates the impact of electric vehicle diffusion on the Korean power market based on an achievable level of market share with different charging demand profiles. Our results reveal the market share of electric vehicles can increase to around 40% of the total market share if the key features of electric vehicles reach a similar level to those of traditional vehicles. In this estimation, an increase in the power market’s system generation costs will reach around 10% of the cost in the baseline scenario, which differs slightly depending on charging demand profiles.

  5. Design features of fans, blowers, and compressors

    Science.gov (United States)

    Cheremisinoff, N. P.; Cheremisinoff, P. N.

    Fan engineering and compression machines are discussed. Basic aspects of fan performance and design are reviewed, and the design and performance characteristics of radial-flow fans, axial-flow fans, and controllable pitch fans are examined in detail. Air-conditioning systems are discussed, and noise, vibration, and mechanical considerations in fans are extensively examined. The thermodynamic principles governing compression machines are reviewed, and piston compressors, rotary compressors, blowers, and centrifugal compressors are discussed.

  6. An object-oriented feature-based design system face-based detection of feature interactions

    International Nuclear Information System (INIS)

    Ariffin Abdul Razak

    1999-01-01

    This paper presents an object-oriented, feature-based design system which supports the integration of design and manufacture by ensuring that part descriptions fully account for any feature interactions. Manufacturing information is extracted from the feature descriptions in the form of volumes and Tool Access Directions, TADs. When features interact, both volumes and TADs are updated. This methodology has been demonstrated by developing a prototype system in which ACIS attributes are used to record feature information within the data structure of the solid model. The system implemented in the C++ programming language and embedded in a menu-driven X-windows user interface to the ACIS 3D Toolkit. (author)

  7. Stego Keys Performance on Feature Based Coding Method in Text Domain

    Directory of Open Access Journals (Sweden)

    Din Roshidi

    2017-01-01

    Full Text Available A main critical factor on embedding process in any text steganography method is a key used known as stego key. This factor will be influenced the success of the embedding process of text steganography method to hide a message from third party or any adversary. One of the important aspects on embedding process in text steganography method is the fitness performance of the stego key. Three parameters of the fitness performance of the stego key have been identified such as capacity ratio, embedded fitness ratio and saving space ratio. It is because a better as capacity ratio, embedded fitness ratio and saving space ratio offers of any stego key; a more message can be hidden. Therefore, main objective of this paper is to analyze three features coding based namely CALP, VERT and QUAD of stego keys in text steganography on their capacity ratio, embedded fitness ratio and saving space ratio. It is found that CALP method give a good effort performance compared to VERT and QUAD methods.

  8. Identifying key features of effective active learning: the effects of writing and peer discussion.

    Science.gov (United States)

    Linton, Debra L; Pangle, Wiline M; Wyatt, Kevin H; Powell, Karli N; Sherwood, Rachel E

    2014-01-01

    We investigated some of the key features of effective active learning by comparing the outcomes of three different methods of implementing active-learning exercises in a majors introductory biology course. Students completed activities in one of three treatments: discussion, writing, and discussion + writing. Treatments were rotated weekly between three sections taught by three different instructors in a full factorial design. The data set was analyzed by generalized linear mixed-effect models with three independent variables: student aptitude, treatment, and instructor, and three dependent (assessment) variables: change in score on pre- and postactivity clicker questions, and coding scores on in-class writing and exam essays. All independent variables had significant effects on student performance for at least one of the dependent variables. Students with higher aptitude scored higher on all assessments. Student scores were higher on exam essay questions when the activity was implemented with a writing component compared with peer discussion only. There was a significant effect of instructor, with instructors showing different degrees of effectiveness with active-learning techniques. We suggest that individual writing should be implemented as part of active learning whenever possible and that instructors may need training and practice to become effective with active learning. © 2014 D. L. Linton et al. CBE—Life Sciences Education © 2014 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

  9. Toward Designing a Quantum Key Distribution Network Simulation Model

    Directory of Open Access Journals (Sweden)

    Miralem Mehic

    2016-01-01

    Full Text Available As research in quantum key distribution network technologies grows larger and more complex, the need for highly accurate and scalable simulation technologies becomes important to assess the practical feasibility and foresee difficulties in the practical implementation of theoretical achievements. In this paper, we described the design of simplified simulation environment of the quantum key distribution network with multiple links and nodes. In such simulation environment, we analyzed several routing protocols in terms of the number of sent routing packets, goodput and Packet Delivery Ratio of data traffic flow using NS-3 simulator.

  10. Cemento-osseous dysplasia of the jaw bones: key radiographic features.

    Science.gov (United States)

    Alsufyani, N A; Lam, E W N

    2011-03-01

    The purpose of this study is to assess possible diagnostic differences between general dentists (GPs) and oral and maxillofacial radiologists (RGs) in the identification of pathognomonic radiographic features of cemento-osseous dysplasia (COD) and its interpretation. Using a systematic objective survey instrument, 3 RGs and 3 GPs reviewed 50 image sets of COD and similarly appearing entities (dense bone island, cementoblastoma, cemento-ossifying fibroma, fibrous dysplasia, complex odontoma and sclerosing osteitis). Participants were asked to identify the presence or absence of radiographic features and then to make an interpretation of the images. RGs identified a well-defined border (odds ratio (OR) 6.67, P < 0.05); radiolucent periphery (OR 8.28, P < 0.005); bilateral occurrence (OR 10.23, P < 0.01); mixed radiolucent/radiopaque internal structure (OR 10.53, P < 0.01); the absence of non-concentric bony expansion (OR 7.63, P < 0.05); and the association with anterior and posterior teeth (OR 4.43, P < 0.05) as key features of COD. Consequently, RGs were able to correctly interpret 79.3% of COD cases. In contrast, GPs identified the absence of root resorption (OR 4.52, P < 0.05) and the association with anterior and posterior teeth (OR 3.22, P = 0.005) as the only key features of COD and were able to correctly interpret 38.7% of COD cases. There are statistically significant differences between RGs and GPs in the identification and interpretation of the radiographic features associated with COD (P < 0.001). We conclude that COD is radiographically discernable from other similarly appearing entities only if the characteristic radiographic features are correctly identified and then correctly interpreted.

  11. Designing attractive gamification features for collaborative storytelling websites.

    Science.gov (United States)

    Hsu, Shang Hwa; Chang, Jen-Wei; Lee, Chun-Chia

    2013-06-01

    Gamification design is considered as the predictor of collaborative storytelling websites' success. Although aforementioned studies have mentioned a broad range of factors that may influence gamification, they neither depicted the actual design features nor relative attractiveness among them. This study aims to identify attractive gamification features for collaborative storytelling websites. We first constructed a hierarchical system structure of gamification design of collaborative storytelling websites and conducted a focus group interview with eighteen frequent users to identify 35gamification features. After that, this study determined the relative attractiveness of these gamification features by administrating an online survey to 6333 collaborative storytelling websites users. The results indicated that the top 10 most attractive gamification features could account for more than 50% of attractiveness among these 35 gamification features. The feature of unpredictable time pressure is important to website users, yet not revealed in previous relevant studies. Implications of the findings were discussed.

  12. Key issues on safety design basis selection and safety assessment

    International Nuclear Information System (INIS)

    An, S.; Togo, Y.

    1976-01-01

    In current fast reactor design in Japan, four design accident conditions and four design seismic conditions are adopted as the design base classifications. These are classified by the considerations on both likelihood of occurrence and the severeness of the consequences. There are several major problem areas in safety design consideration such as core accident problems which include fuel sodium interaction, fuel failure propagation and residual decay heat removal, and decay heat removal systems problems which is more or less the problem of selection of appropriate system and of assurance of high reliability of the system. In view of licensing, two kinds of accidents are postulated in evaluating the adequacy of a reactor site. The one is the ''major accident'' which is the accident to give most severe radiation hazard to the public from technical point of view. The other is the ''hypothetical accident'', induced public accident of which is severer than that of major accident. While the concept of the former is rather unique to Japanese licensing, the latter is almost equivalent to design base hypothetical accident of the US practice. In this paper, design bases selections, key safety issues and some of the licensing considerations in Japan are described

  13. A Distributed Feature-based Environment for Collaborative Design

    Directory of Open Access Journals (Sweden)

    Wei-Dong Li

    2003-02-01

    Full Text Available This paper presents a client/server design environment based on 3D feature-based modelling and Java technologies to enable design information to be shared efficiently among members within a design team. In this environment, design tasks and clients are organised through working sessions generated and maintained by a collaborative server. The information from an individual design client during a design process is updated and broadcast to other clients in the same session through an event-driven and call-back mechanism. The downstream manufacturing analysis modules can be wrapped as agents and plugged into the open environment to support the design activities. At the server side, a feature-feature relationship is established and maintained to filter the varied information of a working part, so as to facilitate efficient information update during the design process.

  14. Multiple Information Fusion Face Recognition Using Key Feature Points

    Directory of Open Access Journals (Sweden)

    LIN Kezheng

    2017-06-01

    Full Text Available After years of face recognition research,due to the effect of illumination,noise and other conditions have led to the recognition rate is relatively low,2 d face recognition technology has couldn’t keep up with the pace of The Times the forefront,Although 3 d face recognition technology is developing step by step,but it has a higher complexity. In order to solve this problem,based on the traditional depth information positioning method and local characteristic analysis methods LFA,puts forward an improved 3 d face key feature points localization algorithm, and on the basis of the trained sample which obtained by complete cluster,further put forward the global and local feature extraction algorithm of weighted fusion. Through FRGC and BU-3DFE experiment data comparison and analysis of the two face library,the method in terms of 3 d face recognition effect has a higher robustness.

  15. The ACR: Advanced design features for a short construction schedule

    International Nuclear Information System (INIS)

    Elgohary, M.; Fairclough, N.

    2003-01-01

    Building on the successful CANDU construction at Qinshan, the ACR-700 is designed with constructability considerations as a major requirement during all project phases from the concept design stage to the detail design stage. A project schedule of 48 months has been developed for the nth ACR unit with a 36 months construction period from First Concrete to Fuel Load. This paper describes some of the advanced design features implemented in the reactor building design in order to achieve this short construction period. These features include large volume concrete pours, prefabricated rebar, composite structures, prefabricated permanent formwork and significant modularization and prefabrication

  16. License Application Design Selection Feature Report: Aging and Blending

    International Nuclear Information System (INIS)

    Coltoni, B.; Anderson, M.J.

    1999-01-01

    The purpose of this document is to evaluate the concepts of Aging and Blending for waste sent to the Monitored Geologic Repository (MGR). These design features are based on pre-emplacement treatment of the waste stream. The envelope of the analysis has been performed under the direction of the License Application Design Selection Team (LADST), which advocated utilizing the Viability Assessment (VA) repository design (DOE 1998c) as the basis. Therefore, this evaluation attempts to modify the VA design only to the extent that Aging and Blending can be accomplished. This modified VA design will be contrasted to the VA Design and the difference in design, costs, and performance will be presented

  17. LMFBR plant design features for sodium spill and fire protection

    International Nuclear Information System (INIS)

    Palm, R.E.

    1982-01-01

    Design features have been developed for an LMFBR plant to protect the concrete structures from potential liquid spills and fires and prevent sodium-concrete reactions. The inclusion of these features in the plant design reduces the severity of design basis accident conditions imposed on containment and other critical plant structures. Steel liners are provided in cells containing radioactive sodium systems, and catch pans are located in non-radioactive sodium system cells. The design requirements and descriptions of each of these protective features are presented. The loading conditions, analytical approach and numerical results are also included. Design of concrete cell structures that are subject to high temperature effects from sodium spills is discussed. The structural design considers the influence of high temperature on design properties of concrete and carbon steel materials based on results of a comprehensive test program. The development of these design features and high temperature design considerations for the Clinch River Breeder Reactor Plant (CRBRP) are presented in this paper

  18. Major NSSS design features of the Korean next generation reactor

    International Nuclear Information System (INIS)

    Kim, Insk; Kim, Dong-Su

    1999-01-01

    In order to meet national needs for increasing electric power generation in the Republic of Korea in the 2000s, the Korean nuclear development group (KNDG) is developing a standardized evolutionary advanced light water reactor (ALWR), the Korean Next Generation Reactor (KNGR). It is an advanced version of the successful Korean Standard Nuclear Power Plant (KSNP) design, which meets utility needs for safety enhancement, performance improvement and ease of operation and maintenance. The KNGR design starts fro the proven design concept of the currently operating KSNPs with uprated power and advanced design features required by the utility. The KNGR design is currently in the final stage of the basic design, and the paper describes the major nuclear steam supply system (NSSS) design features of the KNGR together with introduction of the KNGR development program. (author)

  19. Key-feature questions for assessment of clinical reasoning: a literature review.

    Science.gov (United States)

    Hrynchak, Patricia; Takahashi, Susan Glover; Nayer, Marla

    2014-09-01

    Key-feature questions (KFQs) have been developed to assess clinical reasoning skills. The purpose of this paper is to review the published evidence on the reliability and validity of KFQs to assess clinical reasoning. A literature review was conducted by searching MEDLINE (1946-2012) and EMBASE (1980-2012) via OVID and ERIC. The following search terms were used: key feature; question or test or tests or testing or tested or exam; assess or evaluation, and case-based or case-specific. Articles not in English were eliminated. The literature search resulted in 560 articles. Duplicates were eliminated, as were articles that were not relevant; nine articles that contained reliability or validity data remained. A review of the references and of citations of these articles resulted in an additional 12 articles to give a total of 21 for this review. Format, language and scoring of KFQ examinations have been studied and modified to maximise reliability. Internal consistency reliability has been reported as being between 0.49 and 0.95. Face and content validity have been shown to be moderate to high. Construct validity has been shown to be good using vector thinking processes and novice versus expert paradigms, and to discriminate between teaching methods. The very modest correlations between KFQ examinations and more general knowledge-based examinations point to differing roles for each. Importantly, the results of KFQ examinations have been shown to successfully predict future physician performance, including patient outcomes. Although it is inaccurate to conclude that any testing format is universally reliable or valid, published research supports the use of examinations using KFQs to assess clinical reasoning. The review identifies areas of further study, including all categories of evidence. Investigation into how examinations using KFQs integrate with other methods in a system of assessment is needed. © 2014 John Wiley & Sons Ltd.

  20. Key Success Factors and Guidance for International Collaborative Design Projects

    Directory of Open Access Journals (Sweden)

    Robby Soetanto

    2015-11-01

    Full Text Available In the built environment (BE sector, the co-creation process of design demands understanding of requirements (as viewed by parties involved, mobilisation of tacit knowledge, negotiation, and complex exchange of information. The need to collaborate over distance has further exacerbated the complexity of the process, and, in itself, represents a significant challenge for BE professionals who are increasingly expected to undertake this process within globally distributed virtual teams. The research aims to identify key success factors and develop guidance for international collaborative design projects, via the implementation of collaborative design courses in UK and Canadian universities over three academic years. Questionnaire surveys, focus groups, observation of online meetings, personal reflections provided data for the analysis. The findings reveal the significance of the perceived risk of collaboration and a difference in preferred communication mode between architects and civil/structural engineers. These findings suggest the impact of training in the subject discipline, and that the opportunity for co-located working has helped the development of trust. The guidance is aimed at BE educators who wish to implement this activity in their courses.

  1. Qualitative research methods: key features and insights gained from use in infection prevention research.

    Science.gov (United States)

    Forman, Jane; Creswell, John W; Damschroder, Laura; Kowalski, Christine P; Krein, Sarah L

    2008-12-01

    Infection control professionals and hospital epidemiologists are accustomed to using quantitative research. Although quantitative studies are extremely important in the field of infection control and prevention, often they cannot help us explain why certain factors affect the use of infection control practices and identify the underlying mechanisms through which they do so. Qualitative research methods, which use open-ended techniques, such as interviews, to collect data and nonstatistical techniques to analyze it, provide detailed, diverse insights of individuals, useful quotes that bring a realism to applied research, and information about how different health care settings operate. Qualitative research can illuminate the processes underlying statistical correlations, inform the development of interventions, and show how interventions work to produce observed outcomes. This article describes the key features of qualitative research and the advantages that such features add to existing quantitative research approaches in the study of infection control. We address the goal of qualitative research, the nature of the research process, sampling, data collection and analysis, validity, generalizability of findings, and presentation of findings. Health services researchers are increasingly using qualitative methods to address practical problems by uncovering interacting influences in complex health care environments. Qualitative research methods, applied with expertise and rigor, can contribute important insights to infection prevention efforts.

  2. Exciting Action Photos, Feature Articles, Spread Designs Equal Exciting Sports Coverage.

    Science.gov (United States)

    Konkle, Bruce E.

    1996-01-01

    Discusses what a high school yearbook sports staff should deliver to their peers in overall sports coverage. Suggests that keys to good sports coverage are quality action photos that entice readers, "featurized" sports articles, attention to the overall design of the spreads, team photos that which show faces clearly, and a scoreboard on…

  3. Mechanical design features and challenges for the ITER ICRH antenna

    Energy Technology Data Exchange (ETDEWEB)

    Borthwick, A. [UKAEA/Euratom Fusion Association, Culham Science Centre, Abingdon, Oxon OX14 3DB (United Kingdom)], E-mail: andy.borthwick@yahoo.co.uk; Agarici, G. [Fusion for Energy, Barcelona (Spain); Davis, A. [UKAEA/Euratom Fusion Association, Culham Science Centre, Abingdon, Oxon OX14 3DB (United Kingdom); Dumortier, P.; Durodie, F. [LPP-ERM-KMS, Association EURATOM-Belgian State, Brussels (Belgium); Fanthome, J.; Hamlyn-Harris, C.; Hancock, A.D.; Lockley, D. [UKAEA/Euratom Fusion Association, Culham Science Centre, Abingdon, Oxon OX14 3DB (United Kingdom); Mitteau, R. [Euratom-CEA Association, DSM/IRFM, CEA-Cadarache, 13108 St Paul lez Durance (France); Nightingale, M. [UKAEA/Euratom Fusion Association, Culham Science Centre, Abingdon, Oxon OX14 3DB (United Kingdom); Sartori, R. [Fusion for Energy, Barcelona (Spain); Vulliez, K. [Euratom-CEA Association, DSM/IRFM, CEA-Cadarache, 13108 St Paul lez Durance (France)

    2009-06-15

    The ITER Ion Cyclotron Resonant Heating (ICRH) antenna provides plasma heating at a power of 20 MW. Operation in the ITER environment imposes significant thermal power handling capability, structural integrity, shielding and operations requirements. The design will require a step change over any predecessor in terms of power, scale and complexity. This paper reports the main mechanical design features that address the challenges and often conflicting requirements during the conceptual design phase.

  4. Design features of ACR in severe accident mitigation

    International Nuclear Information System (INIS)

    Shapiro, H.; Krishnan, V.S.; Santamaura, P.; Lekakh, B.; Blahnik, C.

    2007-01-01

    New reactor designs require the evaluation of design alternatives to reduce the radiological risk by preventing severe accidents or by limiting releases from the plant in the event of such accidents. The Advanced CANDU Reactor TM (ACR TM ) design has provisions to prevent and mitigate severe accidents. This paper describes key ACR design features for severe accident mitigation. It provides a high-level overview of the findings to date. Several design provisions have not yet been finalized or decided, but the designers are keenly aware of the SAM concepts and their requirements. The active heat sinks for 'vessels' (i.e., the fuel channels, the calandria vessel, the calandria end-shields and the calandria vault) are all amply capable of dissipating the severe accident heat loads. These heat sinks are designed to be operable under severe accident environmental conditions; however, their operability is yet to be confirmed by assessments. The active heat sinks for the various process vessels are 'backed up' by passive heat sinks (i.e., steaming plus water make-up from the RWS). The supply side of passive heat sinks is simple, rugged, and not vulnerable to failures of plant systems. The importance of the steam relief side is recognized, and the adequate relief capacity will be provided. The passive heat sinks will give the SAM more than 1 day (likely several days) to diagnose the accident and to establish the ultimate heat sinks. The spray system for containment pressure suppression is designed for high reliability and has ample capacity to ensure low containment leakage without external intervention, after which time alternative supply to the sprays can be brought on line manually. The sprays are backed up by the LACs which are assessed for operability following a severe accident. The strong ACR containment will provide a long time of completely passive protection for any severe accident at decay power. Its characteristics are not prone to catastrophic failures. The

  5. Improved design features of KSNP+ BOP Fluid System

    International Nuclear Information System (INIS)

    Park, Heung Gyu; Yoon, Kyung Sup

    2002-01-01

    KOPEC (Korea Power Engineering Co.) in conjunction with the client KHNP (Korea Hydro and Nuclear Power Co.) has been developing the KSNP + (Improved Korean Standard Nuclear Power Plants) design concept since 1998. The main objective of the KSNP + is to enhance safety and economy of KSNP. The design concepts of the KSNP + will be implemented in Shin-Kori Units 1 and 2 Shin-Wolsung Units 1 and 2. This paper provides on an introduction to the improved design features of the KSNP + BOP fluid system consisting of 45 design improvement items. The design improvement concepts of the BOP fluid system have been developed as follows: optimization of system configuration and capacity, simplification of system, and adoption of advanced design features. Improved design features of the BOP fluid system allow additional benefits due to making a contribution to the optimization of plant arrangement and the reduction of operating costs during the plant life time. In conclusion, design improvement to the BOP fluid system have contributed to the KSNP + design concept being more reliable, safe and economically competitive

  6. Design data and safety features of commerical nuclear power plant

    International Nuclear Information System (INIS)

    Heddleson, F.A.

    1976-06-01

    Design data, safety features, and site characteristics are summarized for 34 nuclear power units in 17 power stations in the United States. Six pages of data are presented for each plant, consisting of thermal-hydraulic and nuclear factors, containment features, emergency-core-cooling systems, site features, circulating water system data, and miscellaneous factors. An aerial perspective is also presented for each plant. This volume covers Light Water Reactors (LWRs) with dockets 50-508 through 50-549, four HTGRs--50-171, 50-267, 50-450/451, 50-463/464, the Atlantic Floating Station 50-477/478, and the Clinch River Breeder 50-537

  7. Feature-based component model for design of embedded systems

    Science.gov (United States)

    Zha, Xuan Fang; Sriram, Ram D.

    2004-11-01

    An embedded system is a hybrid of hardware and software, which combines software's flexibility and hardware real-time performance. Embedded systems can be considered as assemblies of hardware and software components. An Open Embedded System Model (OESM) is currently being developed at NIST to provide a standard representation and exchange protocol for embedded systems and system-level design, simulation, and testing information. This paper proposes an approach to representing an embedded system feature-based model in OESM, i.e., Open Embedded System Feature Model (OESFM), addressing models of embedded system artifacts, embedded system components, embedded system features, and embedded system configuration/assembly. The approach provides an object-oriented UML (Unified Modeling Language) representation for the embedded system feature model and defines an extension to the NIST Core Product Model. The model provides a feature-based component framework allowing the designer to develop a virtual embedded system prototype through assembling virtual components. The framework not only provides a formal precise model of the embedded system prototype but also offers the possibility of designing variation of prototypes whose members are derived by changing certain virtual components with different features. A case study example is discussed to illustrate the embedded system model.

  8. Structural health monitoring feature design by genetic programming

    International Nuclear Information System (INIS)

    Harvey, Dustin Y; Todd, Michael D

    2014-01-01

    Structural health monitoring (SHM) systems provide real-time damage and performance information for civil, aerospace, and other high-capital or life-safety critical structures. Conventional data processing involves pre-processing and extraction of low-dimensional features from in situ time series measurements. The features are then input to a statistical pattern recognition algorithm to perform the relevant classification or regression task necessary to facilitate decisions by the SHM system. Traditional design of signal processing and feature extraction algorithms can be an expensive and time-consuming process requiring extensive system knowledge and domain expertise. Genetic programming, a heuristic program search method from evolutionary computation, was recently adapted by the authors to perform automated, data-driven design of signal processing and feature extraction algorithms for statistical pattern recognition applications. The proposed method, called Autofead, is particularly suitable to handle the challenges inherent in algorithm design for SHM problems where the manifestation of damage in structural response measurements is often unclear or unknown. Autofead mines a training database of response measurements to discover information-rich features specific to the problem at hand. This study provides experimental validation on three SHM applications including ultrasonic damage detection, bearing damage classification for rotating machinery, and vibration-based structural health monitoring. Performance comparisons with common feature choices for each problem area are provided demonstrating the versatility of Autofead to produce significant algorithm improvements on a wide range of problems. (paper)

  9. System 80+ design features for severe accident prevention and mitigation

    International Nuclear Information System (INIS)

    Jacob, M.C.; Schneider, R.E.; Finnicum, D.J.

    1993-01-01

    ABB-CE, in cooperation with the US Department of Energy, is working to develop and certify the System 80+ design, which is ABB-CE's standardized evolutionary Advanced Light Water Reactor (ALWR) design. It incorporates design enhancements based on Probabilistic Risk Assessment (PRA) insights, guidance from the EPRI's Utility Requirements Document, and US NRC's Severe Accident Policy. Major severe accident prevention and mitigation design features of the system is discussed along with its conformance to EPRI URD guidance, as applicable. Computer simulation of a best estimate severe accident scenario is presented to illustrate the acceptable containment performance of the design. It is concluded that by considering severe accident prevention and mitigation early in the design process, the System 80+ design represents a robust plant design that has low core damage frequencies, low containment conditional failure probabilities, and acceptable deterministic containment performance under severe accident conditions

  10. Transverse beam splitting made operational: Key features of the multiturn extraction at the CERN Proton Synchrotron

    Directory of Open Access Journals (Sweden)

    A. Huschauer

    2017-06-01

    Full Text Available Following a successful commissioning period, the multiturn extraction (MTE at the CERN Proton Synchrotron (PS has been applied for the fixed-target physics programme at the Super Proton Synchrotron (SPS since September 2015. This exceptional extraction technique was proposed to replace the long-serving continuous transfer (CT extraction, which has the drawback of inducing high activation in the ring. MTE exploits the principles of nonlinear beam dynamics to perform loss-free beam splitting in the horizontal phase space. Over multiple turns, the resulting beamlets are then transferred to the downstream accelerator. The operational deployment of MTE was rendered possible by the full understanding and mitigation of different hardware limitations and by redesigning the extraction trajectories and nonlinear optics, which was required due to the installation of a dummy septum to reduce the activation of the magnetic extraction septum. This paper focuses on these key features including the use of the transverse damper and the septum shadowing, which allowed a transition from the MTE study to a mature operational extraction scheme.

  11. Some key features in the evolution of self psychology and psychoanalysis.

    Science.gov (United States)

    Fosshage, James L

    2009-04-01

    Psychoanalysis, as every science and its application, has continued to evolve over the past century, especially accelerating over the last 30 years. Self psychology has played a constitutive role in that evolution and has continued to change itself. These movements have been supported and augmented by a wide range of emergent research and theory, especially that of cognitive psychology, infant and attachment research, rapid eye movement and dream research, psychotherapy research, and neuroscience. I present schematically some of what I consider to be the key features of the evolution of self psychology and their interconnection with that of psychoanalysis at large, including the revolutionary paradigm changes, the new epistemology, listening/experiencing perspectives, from narcissism to the development of the self, the new organization model of transference, the new organization model of dreams, and the implicit and explicit dimensions of analytic work. I conclude with a focus on the radical ongoing extension of the analyst's participation in the analytic relationship, using, as an example, the co-creation of analytic love, and providing several brief clinical illustrations. The leading edge question guiding my discussion is "How does analytic change occur?"

  12. Bile Routing Modification Reproduces Key Features of Gastric Bypass in Rat.

    Science.gov (United States)

    Goncalves, Daisy; Barataud, Aude; De Vadder, Filipe; Vinera, Jennifer; Zitoun, Carine; Duchampt, Adeline; Mithieux, Gilles

    2015-12-01

    To evaluate the role of bile routing modification on the beneficial effects of gastric bypass surgery on glucose and energy metabolism. Gastric bypass surgery (GBP) promotes early improvements in glucose and energy homeostasis in obese diabetic patients. A suggested mechanism associates a decrease in hepatic glucose production to an enhanced intestinal gluconeogenesis. Moreover, plasma bile acids are elevated after GBP and bile acids are inhibitors of gluconeogenesis. In male Sprague-Dawley rats, we performed bile diversions from the bile duct to the midjejunum or the mid-ileum to match the modified bile delivery in the gut occurring in GBP. Body weight, food intake, glucose tolerance, insulin sensitivity, and food preference were analyzed. The expression of gluconeogenesis genes was evaluated in both the liver and the intestine. Bile diversions mimicking GBP promote an increase in plasma bile acids and a marked improvement in glucose control. Bile bioavailability modification is causal because a bile acid sequestrant suppresses the beneficial effects of bile diversions on glucose control. In agreement with the inhibitory role of bile acids on gluconeogenesis, bile diversions promote a blunting in hepatic glucose production, whereas intestinal gluconeogenesis is increased in the gut segments devoid of bile. In rats fed a high-fat-high-sucrose diet, bile diversions improve glucose control and dramatically decrease food intake because of an acquired disinterest in fatty food. This study shows that bile routing modification is a key mechanistic feature in the beneficial outcomes of GBP.

  13. Design features of an automated entry control system

    International Nuclear Information System (INIS)

    Reynolds, D.A.

    1978-01-01

    Features of an entry control system designed to automatically control access to nuclear facilities is described. Control independent of variable human factors is stressed, but security force action is required for assessment and response as a result of an alarm. A design based on a distributed processing capability is utilized. Flexibility and generality are emphasized in an effort to maximize applicability to the entry-control problem faced by nuclear facilities upgrading security as a result of the Safeguards Program

  14. Design features to facilitate IAEA safeguards at light water reactors

    International Nuclear Information System (INIS)

    Pasternak, T.; Glancy, J.; Goldman, L.; Swartz, J.

    1981-01-01

    Several studies have been performed recently to identify and analyze light water reactor (LWR) features that, if incorporated into the facility design, would facilitate the implementation of International Atomic Energy Agency (IAEA) safeguards. This paper presents results and conclusions of these studies. 2 refs

  15. Key Features of Academic Detailing: Development of an Expert Consensus Using the Delphi Method.

    Science.gov (United States)

    Yeh, James S; Van Hoof, Thomas J; Fischer, Michael A

    2016-02-01

    Academic detailing is an outreach education technique that combines the direct social marketing traditionally used by pharmaceutical representatives with unbiased content summarizing the best evidence for a given clinical issue. Academic detailing is conducted with clinicians to encourage evidence-based practice in order to improve the quality of care and patient outcomes. The adoption of academic detailing has increased substantially since the original studies in the 1980s. However, the lack of standard agreement on its implementation makes the evaluation of academic detailing outcomes challenging. To identify consensus on the key elements of academic detailing among a group of experts with varying experiences in academic detailing. This study is based on an online survey of 20 experts with experience in academic detailing. We used the Delphi process, an iterative and systematic method of developing consensus within a group. We conducted 3 rounds of online surveys, which addressed 72 individual items derived from a previous literature review of 5 features of academic detailing, including (1) content, (2) communication process, (3) clinicians targeted, (4) change agents delivering intervention, and (5) context for intervention. Nonrespondents were removed from later rounds of the surveys. For most questions, a 4-point ordinal scale was used for responses. We defined consensus agreement as 70% of respondents for a single rating category or 80% for dichotomized ratings. The overall survey response rate was 95% (54 of 57 surveys) and nearly 92% consensus agreement on the survey items (66 of 72 items) by the end of the Delphi exercise. The experts' responses suggested that (1) focused clinician education offering support for clinical decision-making is a key component of academic detailing, (2) detailing messages need to be tailored and provide feasible strategies and solutions to challenging cases, and (3) academic detailers need to develop specific skill sets

  16. Evaluating public awareness of new currency design features

    Science.gov (United States)

    DiNunzio, Lisa; Church, Sara E.

    2002-04-01

    One of the goals of the 1996 series design was to integrate highly recognizable features that enable the general public to more easily distinguish counterfeit from genuine notes, thereby reducing the chance of counterfeit notes being passed. The purpose of this study is to evaluate how knowledgeable the public is concerning the new currency, to identify the channels through which the public learns about new currency design, and to assess the usefulness of the new currency's authentication features. Also, the study will serve as a baseline measurement for future design studies and in comparative analysis with other countries. The results of the qualitative research will be described in the following sections of this paper. The quantitative research is scheduled to begin in February 2002, at the same time as the Netherlands' opinion poll of the Euro and NLG-notes in an effort to compare results.

  17. Interactive Universal Design Kiosks: Explanations About Social Inclusion Features in Architectural Design.

    Science.gov (United States)

    Guimarães, Marcelo Pinto; Picceli, Angélica Fátima Baldin; Sabino, Paulo Roberto

    2016-01-01

    This paper details a set of self-supporting and illuminated panels that work together but independently in order to emphasize the explanation of building features and activities that are based on Universal Design guidelines. The exhibition is based on two structures that are arranged in semi-circles (A and B). They are integrated to form a carpeted path where the visitor will be gradually exposed to the concepts related to the principles of Universal Design. Following the sequence of three-dimensional objects and swivelling box elements that support the tactile information on the subject, it is expected that visitors become familiar with each of the principles being demonstrated. Operated by a control system consisting of keys with colour signage, textures and high relief, the panel on the control table allows the user to choose information about paired relationships between some of seven principles contained in printed images about the architectural design on the set of panels. The effectiveness of the composition can be verified by the time people remain enough to hear, see and touch the kiosks for all the information, or by successive visits users make to the setting.

  18. License application design selection feature report: Additive and fillers design feature 19

    International Nuclear Information System (INIS)

    Massari, J.R.

    1999-01-01

    The estimated additional total system life-cycle cost for each of the filler options in 1999 dollars is as follows: $923.4 million for the iron oxide option, $42.4 million to $966.4 million (depending on the extent of surface facility involvement required) for the partial iron shot fill option, $1,012 million for the complete iron shot fill option, and $134.7 million for the integral filler option (Appendix A). All of the filler options evaluated showed improvements in some aspects of pre- and post-closure waste package and repository performance. However, all of the options, except for the integral filler option, negatively impacted other areas of performance, required modification to surface facility design and operations, and invoked additional uncertainty. The iron oxide filler option will require further testing to measure thermal conductivity to ensure that peak cladding temperatures will not exceed the 350 C limit. The complete iron shot fill option may require structural improvements to the waste package design (use of partial shot fill may eliminate this concern). Both the iron shot and iron oxide options will also require further testing to confirm that the conceptual loading strategy will efficiently load a waste package in a timely manner. In addition, both shot and oxide options will require further testing to develop models for their potential to provide resistance to water flow, and, in the case of iron shot, act as an oxygen getter. Finally, uncertainty also exists as to whether the iron shot option will damage the cladding if sufficient corrosion of the shot occurs. Based on the results presented in this evaluation, the integral filler option appears to be the simplest and most cost efficient method for achieving modest improvements in pre- and post-closure performance. Since unqualified inputs were used in the development of this evaluation, they should be considered TBV (to be verified). This document will not directly support any construction

  19. EPR design features to mitigate severe accident challenges

    International Nuclear Information System (INIS)

    Mazurkiewicz, S.M.; Fischer, M.; Bittermann, D.

    2005-01-01

    The EPR, an evolutionary pressurized water reactor (PWR), is a 4300-4500 MWth that incorporates proven technology within an optimized configuration to enhance safety. EPR was originally developed through a joint effort between Framatome ANP and Siemens by incorporating the best technological features from the French and German nuclear reactor fleets into a cost-competitive product. Commercial EPR units are currently being built in Finland at the Olkiluoto site, and planned for France at the Flamanville site. In recent months, Framatome ANP announced their intention to market the EPR units to China in response to a request for vendor bids as well as their intent to pursue design certification in the United States under 10CFR52. The EPR safety philosophy is based on a deterministic consideration of defense-in-depth complemented by probabilistic analyses. Not only is the EPR designed to prevent and mitigate design basis accidents (DBAs), it employs an extra level of safety associated with severe accident response. Therefore, as a design objective, features are included to ensure that radiological consequences are limited such that the need for stringent counter measures, such as evacuation and relocation of the nearby population, can be reasonably excluded. This paper discusses some of the innovative features of the EPR to address severe accident challenges. (author)

  20. Simple Public Key Infrastructure Protocol Analysis and Design

    National Research Council Canada - National Science Library

    Vidergar, Alexander G

    2005-01-01

    ...). This thesis aims at proving the applicability of the Simple Public Key Infrastructure (SPKI) as a means of PKC. The strand space approach of Guttman and Thayer is used to provide an appropriate model for analysis...

  1. EC6 design features and pre-project licensing review

    Energy Technology Data Exchange (ETDEWEB)

    Yu, S.; Lee, A.G.; Dinh, N.B.; Soulard, M. [CANDU Energy Inc., Mississauga, Ontario, (Canada)

    2013-07-01

    The Enhanced CANDU 6 (EC6) is the new Generation III CANDU reactor design that meets the most up to date Canadian regulatory requirements and customer expectations. Candu Energy Inc. is finalizing development of the EC6 which incorporates the CANDU 6's well-proven features, and adds enhancements that strengthened reactor safety margin and improved operability. The EC6 builds on the proven high performance design and the defence-in-depth features of CANDU 6 units, and has incorporated extensive operational feedback including lessons learned from Fukushima. This paper will provide status of the engineering program including progress on the pre-licensing review of the EC6 design by the Canadian Regulator, CNSC, and will also highlight the design and safety enhancements incorporated in the EC6 product. Safety enhancements to meet safety goals and to improve robustness of systems to respond to design basis accidents and beyond design basis accidents include: new severe accident recovery and heat removal system; improved emergency heat removal system; faster shutoff rods with improved safety margins; mechanical guaranteed shutdown rods; daily load cycling capability; robust containment with containment filter venting system; and improved backed-up electrical supply and cooling services. (author)

  2. Design and physical features of inductive coaxial copper vapor lasers

    Energy Technology Data Exchange (ETDEWEB)

    Batenin, V. M. [Russian Academy of Sciences, Joint Institute for High Temperatures (Russian Federation); Kazaryan, M. A. [Russian Academy of Sciences, Lebedev Physical Institute (Russian Federation); Karpukhin, V. T. [Russian Academy of Sciences, Joint Institute for High Temperatures (Russian Federation); Lyabin, N. A. [Istok Research and Production Corporation (Russian Federation); Malikov, M. M., E-mail: mmalikov@oivtran.ru [Russian Academy of Sciences, Joint Institute for High Temperatures (Russian Federation)

    2016-11-15

    A physical model of a copper vapor laser pumped by a pulse-periodic inductive (electrodeless) discharge is considered. The feasibility of efficient laser pumping by an inductive discharge and reaching high output parameters comparable to those of conventional copper vapor lasers pumped by a longitudinal electrode discharge is demonstrated. The design and physical features of an inductive copper vapor laser with an annular working volume are discussed.

  3. Designing for Communication: The Key to Successful Desktop Publishing.

    Science.gov (United States)

    McCain, Ted D. E.

    Written for those who are new to design and page layout, this book focuses on providing novice desktop publishers with an understanding of communication, graphic design, typography, page layout, and page layout techniques. The book also discusses how people read, design as a consequence of understanding, and the principles of page layout. Chapters…

  4. A key design to prolong lifetime of wireless sensor network

    International Nuclear Information System (INIS)

    Qiu, Bo; Chen, XiQiu; Wu, Qi

    2016-01-01

    In order to solve the contradiction between the connectivity of the wireless sensor network and the key storage consumption, under the premise of reducing network storage consumption, the key pre-distribution management scheme with higher connectivity rate is proposed using the hexagonal network deployment information, which adopts the idea of the matrix space for the square deployment information strategy to reduce the burden of the network storage. Ability against the capture attack is improved obviously. The results show that contradiction between the network connectivity rate and the energy consumption has a better solution, and the proposed algorithm is suitable for the wireless sensor networks of energy limited.

  5. Key points for the design of Mox facilities

    International Nuclear Information System (INIS)

    Ducroux, R.; Gaiffe, L.; Dumond, S.; Cret, L.

    1998-01-01

    The design of a MOX fuel fabrication facility involves specific technical difficulties: - Process aspects: for example, its is necessary to meet the stringent requirements on the end products, while handling large quantities of powders and pellets; - Safety aspects: for example, containment of radioactive materials requires to use gloveboxes, to design process equipment so as to limit dispersion to the gloveboxes and to use systems for dust collection. - Technological aspects: for example, it is necessary to take into account maintenance early in the design, in order to lower the operation costs and lower the dose to the personnel. - Quality control and information systems: for example, it is necessary to be able to trace all the different products (powder lots, pellets, rods, assemblies). The design methods and organization set-up by COGEMA enables to master these technical difficulties during the different design steps and to obtain a MOX fabrication facility at the best performance versus cost compromise. These design methods rely mainly on: - taking into account all the different above mentioned constraints from the very beginning of the design process (by using the know-how resulting from experience feed-back, and also specific design tools developed by COGEMA and SGN); - launching a technical development and testing program at the beginning of the project and incorporating its results in the course of the design. (author)

  6. The design and safety features of the IRIS reactor

    International Nuclear Information System (INIS)

    Carelli, Mario D.; Conway, L.E.; Oriani, L.; Petrovic, B.; Lombardi, C.V.; Ricotti, M.E.; Barroso, A.C.O.; Collado, J.M.; Cinotti, L.; Todreas, N.E.; Grgic, D.; Moraes, M.M.; Boroughs, R.D.; Ninokata, H.; Ingersoll, D.T.; Oriolo, F.

    2004-01-01

    Salient features of the International Reactor Innovative and Secure (IRIS) are presented here. IRIS, an integral, modular, medium size (335 MWe) PWR, has been under development since the turn of the century by an international consortium led by Westinghouse and including over 20 organizations from nine countries. Described here are the features of the integral design which includes steam generators, pumps and pressurizer inside the vessel, together with the core, control rods, and neutron reflector/shield. A brief summary is provided of the IRIS approach to extended maintenance over a 48-month schedule. The unique IRIS safety-by-design approach is discussed, which, by eliminating accidents, at the design stage, or decreasing their consequences/probabilities when outright elimination is not possible, provides a very powerful first level of defense in depth. The safety-by-design allows a significant reduction and simplification of the passive safety systems, which are presented here, together with an assessment of the IRIS response to transients and postulated accidents

  7. An ontology design pattern for surface water features

    Science.gov (United States)

    Sinha, Gaurav; Mark, David; Kolas, Dave; Varanka, Dalia; Romero, Boleslo E.; Feng, Chen-Chieh; Usery, E. Lynn; Liebermann, Joshua; Sorokine, Alexandre

    2014-01-01

    Surface water is a primary concept of human experience but concepts are captured in cultures and languages in many different ways. Still, many commonalities exist due to the physical basis of many of the properties and categories. An abstract ontology of surface water features based only on those physical properties of landscape features has the best potential for serving as a foundational domain ontology for other more context-dependent ontologies. The Surface Water ontology design pattern was developed both for domain knowledge distillation and to serve as a conceptual building-block for more complex or specialized surface water ontologies. A fundamental distinction is made in this ontology between landscape features that act as containers (e.g., stream channels, basins) and the bodies of water (e.g., rivers, lakes) that occupy those containers. Concave (container) landforms semantics are specified in a Dry module and the semantics of contained bodies of water in a Wet module. The pattern is implemented in OWL, but Description Logic axioms and a detailed explanation is provided in this paper. The OWL ontology will be an important contribution to Semantic Web vocabulary for annotating surface water feature datasets. Also provided is a discussion of why there is a need to complement the pattern with other ontologies, especially the previously developed Surface Network pattern. Finally, the practical value of the pattern in semantic querying of surface water datasets is illustrated through an annotated geospatial dataset and sample queries using the classes of the Surface Water pattern.

  8. Design features of SMART for barge mounted application

    International Nuclear Information System (INIS)

    Doo-Jeong Lee; Ju-Hyeon Yoon; Ju-Pyung Kim; Jong-In Kim; Moon-Hee Chang

    2000-01-01

    SMART is an integral reactor of 330 MWt capacity with passive safety features being developed for a wide range of applications including the barge mounted co-generation plant. Its design strives to combine the firmly-established commercial reactor design with new advanced technologies. Thus the use of the industry proven KOFA (Korea Optimized Fuel Assembly) based nuclear fuels is pursued while such radically new technologies as self-pressurizing pressurizer, helical once-through steam generators, and advanced control concepts are being developed. The safety of SMART centers around enhancing the inherent safety characteristics of the reactor and salient features include low core power density, integral arrangement to eliminate large break loss of coolant accident, etc. The progression of emergency situations into accidents is prevented with a number of advanced engineered safety features such as Passive Residual Heat Removal System, Passive Emergency Core Cooling System, Safeguard Vessel, Passive Containment Over-pressure Protection. This paper presents the status of current SMART development, characteristics of SMART safety systems and the possibility of SMART application to barge mounted environment. (author)

  9. Design as Key to Unlock the Wicked Problem of Sustainability

    DEFF Research Database (Denmark)

    Skjold, Else; Ræbild, Ulla; Hasling, Karen Marie

    2017-01-01

    How might we as researchers within the design community reach out and create new knowledge and value in close collaboration with a company, and at the same time contribute to a sustainable development? In this paper, we address the question of How and with whom do we re-do, by proposing multiple...... case on which the paper builds and account for the applied multiple perspectives research design. Lastly, we discuss how the construct has supported a less compartmentalised understanding of sustainability within the company, and furthered insights on how design can be a driver for sustainability...... perspectives research as a way to unlock the potential of design thinking as a fundamentally integrative discipline. Hence, the aim of the paper is to show and discuss the ways in which a research design constructed by several perspectives can enable an actual impact. We will present the company collaboration...

  10. Design, construction and operation features of high-rise structures

    Science.gov (United States)

    Mylnik, Alexey; Mylnik, Vladimir; Zubeeva, Elena; Mukhamedzhanova, Olga

    2018-03-01

    The article considers design, construction and operation features of high-rise facilities. The analysis of various situations, that come from improper designing, construction and operation of unique facilities, is carried out. The integrated approach is suggested, when the problems of choosing acceptable constructional solutions related to the functional purpose, architectural solutions, methods of manufacturing and installation, operating conditions for unique buildings and structures are being tackled. A number of main causes for the emergency destruction of objects under construction and operation is considered. A number of measures are proposed on the basis of factor classification in order to efficiently prevent the situations, when various negative options of design loads and emergency impacts occur.

  11. Improving Latino Children's Early Language and Literacy Development: Key Features of Early Childhood Education within Family Literacy Programmes

    Science.gov (United States)

    Jung, Youngok; Zuniga, Stephen; Howes, Carollee; Jeon, Hyun-Joo; Parrish, Deborah; Quick, Heather; Manship, Karen; Hauser, Alison

    2016-01-01

    Noting the lack of research on how early childhood education (ECE) programmes within family literacy programmes influence Latino children's early language and literacy development, this study examined key features of ECE programmes, specifically teacher-child interactions and child engagement in language and literacy activities and how these…

  12. Seismic design features of the ACR Nuclear Power Plant

    International Nuclear Information System (INIS)

    Elgohary, M.; Saudy, A.; Aziz, T.

    2003-01-01

    features including the design soil/rock foundation profiles and input GRS that are used in the seismic design and qualification of the ACR are presented. It is concluded that the selected seismic design input parameters for the ACR plant meet current international technical and regulatory requirements. (author)

  13. Design features of Advanced Power Reactor (APR) 1400 steam generator

    International Nuclear Information System (INIS)

    Park, Tae-Jung; Park, Jun-Soo; Kim, Moo-Yong

    2004-01-01

    Advanced Power Reactor 1400 (APR 1400) which is to achieve the improvement of the safety and economical efficiency has been developed by Korea Hydro and Nuclear Power Co., Ltd. (KHNP) with the support from industries and research institutes. The steam generator for APR 1400 is an evolutionary type from System 80 + , which is the recirculating U-tube heat exchanger with integral economizer. Compared to the System 80 + steam generator, it is focused on the improved design features, operating and design conditions of APR 1400 steam generator. Especially, from the operation experience of Korean Standard Nuclear Power Plant (KSNP) steam generator, the lessons-learned measures are incorporated to prevent the tube wear caused by flow-induced vibration (FIV). The concepts for the preventive design features against FIV are categorized to two fields; flow distribution and dynamic response characteristics. From the standpoint of flow distribution characteristics, the egg-crate flow distribution plate (EFDP) is installed to prevent the local excessive flow loaded on the most susceptible tube to wear. The parametric study is performed to select the optimum design with the efficient mitigation of local excessive flow. ATHOS3 Mod-01 is used and partly modified to analyze the flow field of the APR 1400 steam generator. In addition, the upper tube bundle support is designed to eliminate the presence of tube with a low natural frequency. Based on the improved upper tube bundle support, the modal analysis is performed and compared with that of System 80 + . Using the results of flow distribution and modal analysis, the two mechanisms of flow-induced vibration are investigated; fluid-elastic instability (FEI) and random turbulence excitation (RTE). (authors)

  14. Design features and operating characteristics of the MC-50 cyclotron

    International Nuclear Information System (INIS)

    Bak, Hae Ill; Bak, Joo Shik

    1989-01-01

    The MC-50 cyclotron at Korean Cancer Center Hospital is now operational for neutron therapy and medical radioisotope production. Design features, mechanical structures and operating characteristics of the MC-50 are described in this paper. Optimum operating condition for this cyclotron has been determined by the repetitive running, and the performances of the internal beam have been investigated through the measurements of intensity and spatial distribution of the internal beam as a function of the radius of the cyclotron. Routinely, the 40 μA of 50 MeV protons have been obtained at first Faraday cup with a extraction efficiency of 61%. (Author)

  15. Space Station services and design features for users

    Science.gov (United States)

    Kurzhals, Peter R.; Mckinney, Royce L.

    1987-01-01

    The operational design features and services planned for the NASA Space Station will furnish, in addition to novel opportunities and facilities, lower costs through interface standardization and automation and faster access by means of computer-aided integration and control processes. By furnishing a basis for large-scale space exploitation, the Space Station will possess industrial production and operational services capabilities that may be used by the private sector for commercial ventures; it could also ultimately support lunar and planetary exploration spacecraft assembly and launch facilities.

  16. Westinghouse AP1000 advanced passive plant: design features and benefits

    International Nuclear Information System (INIS)

    Walls, S.J.; Cummins, W.E.

    2003-01-01

    The Westinghouse AP1000 Program is aimed at implementing the AP1000 plant to provide a further major improvement in plant economics while maintaining the passive safety advantages established by the AP600. An objective is to retain to the maximum extent possible the plant design of the AP600 so as to retain the licensing basis, cost estimate, construction schedule, modularization scheme, and the detailed design from the AP600 program. Westinghouse and the US Nuclear Regulatory Commission staff have embarked on a program to complete Design Certification for the AP1000 by 2004. A pre-certification review phase was completed in March 2002 and was successful in establishing the applicability of the AP600 test program and AP600 safety analysis codes to the AP1000 Design Certification. On March 28, 2002, Westinghouse submitted to US NRC the AP1000 Design Control Document and Probabilistic Risk Assessment, thereby initiating the formal design certification review process. The results presented in these documents verify the safety performance of the API 000 and conformance with US NRC licensing requirements. Plans are being developed for implementation of a series of AP1000 plants in the US. Key factors in this planning are the economics of AP1000, and the associated business model for licensing, constructing and operating these new plants. Similarly plans are being developed to get the AP1000 design reviewed for use in the UK. Part of this planning has been to examine the AP1000 design relative to anticipated UK safety and licensing issues. (author)

  17. The cue is key : design for real-life remembering

    NARCIS (Netherlands)

    Hoven, van den E.A.W.H.; Eggen, J.H.

    2014-01-01

    This paper aims to put the memory cue in the spotlight. We will show how memory cues are incorporated in the area of interaction design. The focus will be on external memory cues: cues that exist outside the human mind but have an internal effect on memory reconstruction. Examples of external cues

  18. Process understanding and cooperative design. Keys to high quality automation

    International Nuclear Information System (INIS)

    Tommila, T.; Heinonen, R.

    1995-01-01

    A systematic approach to the specification of process control systems, and four practical methods supporting user participation and interdisciplinary co-operation are described. The main steps of the design approach are: (1) hierarchical decomposition of the plant to process items of different types; (2) analysis and definition of requirements and control strategies associated with each process item; (3) definition of automation degree; and (4) functional specification of the control system and its user interface. The specification language used for this step is a combination of principles found in object oriented design, structured analysis as well as new language standards for programmable controllers and open information systems. The design review methods presented include structured control strategy meetings, safety analysis of sequential controls, review of graphic displays, and a usability questionnaire for existing plants. These methods can be used to elicit users' needs and operational experience, to gain a common understanding of the process functionality, or to detect errors in design specifications or in existing systems. (8 refs., 9 figs.)

  19. Design features of HTMR-Hybrid Toroidal Magnet Tokamak Reactor

    International Nuclear Information System (INIS)

    Rosatelli, F.; Avanzini, P.G.; Brunelli, B.; Derchi, D.; Magnasco, M.; Grattarola, M.; Peluffo, M.; Raia, G.; Zampaglione, V.

    1985-01-01

    The HTMR (Hybrid Toroidal Magnet Tokamak Reactor) conceptual design is aimed to demonstrate the feasibility of a Tokamak reactor which could fulfill the scientific and technological objectives expected from next generation devices (e.g. INTOR-NET) with size and costs as small as possible. An hybrid toroidal field magnet, made up by copper and superconducting coils, seems to be a promising solution, allowing a considerable flexibility in machine performances, so as to gain useful margins in front of the uncertainties in confinement time scaling laws and beta and plasma density limits. In this paper the authors describe the optimization procedure for the hybrid magnet configuration, the main design features of HTMR and the preliminary mechanical calculations of the superconducting toroidal coils

  20. Design features of HTMR-hybrid toroidal magnet tokamak reactor

    International Nuclear Information System (INIS)

    Rosatelli, F.; Avanzini, P.G.; Derchi, D.; Magnasco, M.; Grattarola, M.; Peluffo, M.; Raia, G.; Brunelli, B.; Zampaglione, V.

    1984-01-01

    The HTMR (Hybrid Toroidal Magnet Tokamak Reactor) conceptual design is aimed to demonstrate the feasibility of a Tokamak reactor which could fulfil the scientific and technological objectives expected from next generation devices with size and costs as small as possible. A hybrid toroidal field magnet, made up by copper and superconducting coils, seems to be a promising solution, allowing a considerable flexibility in machine performances, so as to gain useful margins in front of the uncertainties in confinement time scaling laws and beta and plasma density limits. The optimization procedure for the hybrid magnet, configuration, the main design features of HTMR and the preliminary mechanical calculations of the superconducting toroidal coils are described. (author)

  1. Hypertension Is a Key Feature of the Metabolic Syndrome in Subjects Aging with HIV

    DEFF Research Database (Denmark)

    Martin-Iguacel, Raquel; Negredo, Eugènia; Peck, Robert

    2016-01-01

    to predispose to these metabolic complications and to the excess risk of CVD observed in the HIV population. The metabolic syndrome (MS) represents a clustering of RF for CVD that includes abdominal obesity, hypertension, dyslipidemia and insulin resistance. Hypertension is a prevalent feature of the MS in HIV...

  2. Software features and applications in process design, integration and operation

    Energy Technology Data Exchange (ETDEWEB)

    Dhole, V. [Aspen Tech Limited, Warrington (United Kingdom)

    1999-02-01

    Process engineering technologies and tools have evolved rapidly over the last twenty years. Process simulation/modeling, advanced process control, on-line optimisation, production planning and supply chain management are some of the examples of technologies that have rapidly matured from early commercial prototypes and concepts to established tools with significant impact on profitability of process industry today. Process Synthesis or Process Integration (PI) in comparison is yet to create its impact and still remains largely in the domain of few expert users. One of the key reasons as to why PI has not taken off is because the PI tools have not become integral components of the standard process engineering environments. On the last 15 years AspenTech has grown from a small process simulation tool provider to a large multinational company providing a complete suite of process engineering technologies and services covering process design, operation, planning and supply chain management. Throughout this period, AspenTech has acquired experience in rapidly evolving technologies from their early prototype stage to mature products and services. The paper outlines AspenTech`s strategy of integrating PI with other more established process design and operational improvement technologies. The paper illustrates the key elements of AspenTech`s strategy via examples of software development initiatives and services projects. The paper also outlines AspenTech`s future vision of the role of PI in process engineering. (au)

  3. An Ontology Design Pattern for Surface Water Features

    Energy Technology Data Exchange (ETDEWEB)

    Sinha, Gaurav [Ohio University; Mark, David [University at Buffalo (SUNY); Kolas, Dave [Raytheon BBN Technologies; Varanka, Dalia [U.S. Geological Survey, Rolla, MO; Romero, Boleslo E [University of California, Santa Barbara; Feng, Chen-Chieh [National University of Singapore; Usery, Lynn [U.S. Geological Survey, Rolla, MO; Liebermann, Joshua [Tumbling Walls, LLC; Sorokine, Alexandre [ORNL

    2014-01-01

    Surface water is a primary concept of human experience but concepts are captured in cultures and languages in many different ways. Still, many commonalities can be found due to the physical basis of many of the properties and categories. An abstract ontology of surface water features based only on those physical properties of landscape features has the best potential for serving as a foundational domain ontology. It can then be used to systematically incor-porate concepts that are specific to a culture, language, or scientific domain. The Surface Water ontology design pattern was developed both for domain knowledge distillation and to serve as a conceptual building-block for more complex surface water ontologies. A fundamental distinction is made in this on-tology between landscape features that act as containers (e.g., stream channels, basins) and the bodies of water (e.g., rivers, lakes) that occupy those containers. Concave (container) landforms semantics are specified in a Dry module and the semantics of contained bodies of water in a Wet module. The pattern is imple-mented in OWL, but Description Logic axioms and a detailed explanation is provided. The OWL ontology will be an important contribution to Semantic Web vocabulary for annotating surface water feature datasets. A discussion about why there is a need to complement the pattern with other ontologies, es-pecially the previously developed Surface Network pattern is also provided. Fi-nally, the practical value of the pattern in semantic querying of surface water datasets is illustrated through a few queries and annotated geospatial datasets.

  4. Composite smile designs: the key to dental artistry.

    Science.gov (United States)

    Portalier, L

    1997-01-01

    Patients seeking to improve the appearance of their smiles have driven the profession toward more challenges in esthetic dentistry to answer their needs. Better smiles are being equated with better living. Direct composite veneering has gained tremendous popularity over the past few years because the procedure can be done in one single appointment for a reasonable fee with acceptable results. Materials recently put on the market require stratification build-up techniques to allow for the best natural results. In addition, the procedure gives patients the freedom of live communication and dentists the emotive artistic recreation of a smile composition in which anterior teeth can be designed and redesigned through freehand craftmanship, until both patient and dentist are pleased with the results. This review highlights the benefits of direct composite veneering, a very unique process to investigate more about tooth and smile designs, and suggests more effective communication between patient and dentist in order to achieve predictable results.

  5. Key elements for designing a strategy to generate social and ...

    African Journals Online (AJOL)

    For example, with the growth of social media (O'Brien, 2011), the number ... three tourism journals for the past 20 years. This goes .... The festival. Vision, mission, motivation of the festival .... designer of Boom, the festival is “a space for an experience” to “gather ... as expected: e.g. an app to support car-sharing. In spite of ...

  6. 'Practicality' as a key constraint to HLW repository design

    International Nuclear Information System (INIS)

    Kitayama, Kazumi; Sakabe, Yasushi; Ishiguro, Katsuhiko

    2007-01-01

    Designs of repositories in Japan for HLW have focused very much on demonstration of post-closure safety. Safety can be assured using very simple assessment techniques, which make many conservative simplifications. Such a situation is reasonable for the early stages of generic concept demonstration, but becomes less appropriate as NUMO moves towards siting, where a number of issues involved with construction and operation of a repository - generally grouped together as 'practicality'. The engineering logistics and conventional safety of repository construction and operation have been relatively little studied and present major challenges. Current designs emphasise a minimum of infrastructure in the emplacement tunnels and remote-handled operation. This would be difficult enough, but such operations need to be carried out to strict quality limits and need to be robust in the event of equipment failure or disruptive events. The paper will first examine how designs can be modified from the viewpoint of logistics. The implications of such modifications on operational robustness and associated safety in case of perturbation scenarios are then considered. (author)

  7. Key issues in theoretical and functional pneumatic design

    Science.gov (United States)

    Xu, Z. G.; Yang, D. Y.; Liu, W. M.; Liu, T. T.

    2017-10-01

    This paper studies the energy release of the pneumatic engine in different thermodynamic processes, the isothermal process is the highest power output process, while adiabatic process is the lowest energy output process, and the energy release of the pneumatic engine is a multi-state thermodynamic process between them. Therefore heat exchanging should be increased between the pneumatic engine and the outer space, the gas expansion process in the cylinder should be as close as possible to the isothermal process. Heat exchange should be increased between the cylinder and the external spaces. Secondly, the fin structure is studied to increase the heat exchanging between the cylinder body and the outside space. The upper part has fin structures and the lower cylinder has no fin structure, this structure improved the working efficiency of pneumatic engine. Finally the cam and the hydraulic bottle of pneumatic engines are designed. Simulation and theoretical calculation are used to the analysis of the whole structure, which lay the foundation for the manufacturing and design of the pneumatic engines.

  8. Evaluation of design feature No.20 -- Ground support options

    International Nuclear Information System (INIS)

    Duan, F.

    2000-01-01

    Ground support options are primarily evaluated for emplacement drifts while ground support systems for non-emplacement openings such as access mains and ventilation drifts are not evaluated against LADS evaluation criteria in this report. Considerations include functional requirements for ground support, the use of a steel-lined system, and the feasibility of using an unlined ground support system principally with grouted rock bolts for permanent ground support. The feature evaluation also emphasizes the postclosure effects of ground support materials on waste isolation and the preclosure aspects such as durability, maintainability, constructibility, safety, engineering acceptability, and cost. This evaluation is to: (A) Review the existing analyses, reports, and studies regarding this design feature, and compile relevant information on performance characteristics. (B) Develop an appropriate evaluation approach for evaluating ground support options against evaluation criteria provided by the LADS team. (C) Evaluate ground support options not only for their preclosure performance in terms of drift stability, material durability, maintenance, constructibility, and cost, but also for their postclosure performance in terms of chemical effects of ground support materials (i.e., concrete, steel) on waste isolation and radionuclide transport. Specifically, the scope for ground support options evaluation include: (1) all steel-lined drifts (no cementitious materials), (2) unlined drifts with minimum cementitious materials (e.g., grout for rockbolts), and (3) concrete-lined drifts, with the focus on the postclosure acceptability evaluation. In addition, unlined drifts with zero cementitious materials (e.g., use of frictional bolts such as split sets, Swellex bolts) are briefly discussed. (D) Identify candidate ground support systems that have the potential to enhance the repository performance based on the feature evaluation. and (E) Provide conclusions and recommendations

  9. Key Design Requirements for Long-Reach Manipulators

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, D.S.

    2001-01-01

    Long-reach manipulators differ from industrial robots and teleoperators typically used in the nuclear industry in that the aspect ratio (length to diameter) of links is much greater and link flexibility, as well as joint or drive train flexibility, is likely to be significant. Long-reach manipulators will be required for a variety of applications in the Environmental Restoration and Waste Management Program. While each application will present specific functional, kinematic, and performance requirements, an approach for determining the kinematic applicability and performance characteristics is presented, with a focus on waste storage tank remediation. Requirements are identified, kinematic configurations are considered, and a parametric study of link design parameters and their effects on performance characteristics is presented.

  10. Key design requirements for long-reach manipulators

    International Nuclear Information System (INIS)

    Kwon, D.S.; March-Leuba, S.; Babcock, S.M.; Hamel, W.R.

    1993-09-01

    Long-reach manipulators differ from industrial robots and teleoperators typically used in the nuclear industry in that the aspect ratio (length to diameter) of links is much greater and link flexibility, as well as joint or drive train flexibility, is likely to be significant. Long-reach manipulators will be required for a variety of applications in the Environmental Restoration and Waste Management Program. While each application will present specific functional kinematic, and performance requirements an approach for determining the kinematic applicability and performance characteristics is presented, with a focus on waste storage tank remediation. Requirements are identified, kinematic configurations are considered, and a parametric study of link design parameters and their effects on performance characteristics is presented

  11. Key Design Requirements for Long-Reach Manipulators

    International Nuclear Information System (INIS)

    Kwon, D.S.

    2001-01-01

    Long-reach manipulators differ from industrial robots and teleoperators typically used in the nuclear industry in that the aspect ratio (length to diameter) of links is much greater and link flexibility, as well as joint or drive train flexibility, is likely to be significant. Long-reach manipulators will be required for a variety of applications in the Environmental Restoration and Waste Management Program. While each application will present specific functional, kinematic, and performance requirements, an approach for determining the kinematic applicability and performance characteristics is presented, with a focus on waste storage tank remediation. Requirements are identified, kinematic configurations are considered, and a parametric study of link design parameters and their effects on performance characteristics is presented

  12. Design Features of Hardening Turners with Outstripping Plastic Deformation

    Directory of Open Access Journals (Sweden)

    V. M. Yaroslavtsev

    2014-01-01

    Full Text Available An efficiency of the cutting method with outstripping plastic deformation (OPD in lathe works is defined in many respects by design features of the add-on devices for mechanical hardening of a cut-off layer material in the course of cutting. Applied on lathes, deforming OPD devices can have differing dimensions, placement on the lathe, drive type (manual, electric, hydraulic, pneumatic, pneumohydraulic, electromagnetic, and autonomy degree towards the metalcutting equipment and industrial equipment.At the same time there are a number of inherent design features of work-hardening devices the modernized lathes with OPD use for machining. Now the OPD standard devices implement two principle construction options: loading device is placed on the machine or on the OPD slide support separate of the tool, or it is structurally aligned with the cutting tool. In the latter case the OPD device for turning is called a tool mandrel, which is mounted in a tool post of the machine or, at large dimensions, such a mandrel is mounted on the machine instead of the tool mandrel.When designing the OPD devices, is important to take into consideration production requirements and recommendations for the technological equipment, developed in the course of creation, working off and introduction of such installations for mechanical hardening of material. In compliance with it, OPD devices, their placement on the machine, and working displacements shouldn't limit technological capabilities of the applied metal-cutting equipment. OPD stresses have to be smoothly regulated, with maximum loads being limited to admissible values for the machine model to be modernized. It is necessary to ensure synchronized longitudinal and cross displacements of the cutting tool and OPD hardener with respect to the axis of billet rotation to enable regulation and readjustment of the hardener and tool placement. It ought to foresee the increased mobile components rigidity and manufacturing

  13. Key structural features of nonsteroidal ligands for binding and activation of the androgen receptor.

    Science.gov (United States)

    Yin, Donghua; He, Yali; Perera, Minoli A; Hong, Seoung Soo; Marhefka, Craig; Stourman, Nina; Kirkovsky, Leonid; Miller, Duane D; Dalton, James T

    2003-01-01

    The purposes of the present studies were to examine the androgen receptor (AR) binding ability and in vitro functional activity of multiple series of nonsteroidal compounds derived from known antiandrogen pharmacophores and to investigate the structure-activity relationships (SARs) of these nonsteroidal compounds. The AR binding properties of sixty-five nonsteroidal compounds were assessed by a radioligand competitive binding assay with the use of cytosolic AR prepared from rat prostates. The AR agonist and antagonist activities of high-affinity ligands were determined by the ability of the ligand to regulate AR-mediated transcriptional activation in cultured CV-1 cells, using a cotransfection assay. Nonsteroidal compounds with diverse structural features demonstrated a wide range of binding affinity for the AR. Ten compounds, mainly from the bicalutamide-related series, showed a binding affinity superior to the structural pharmacophore from which they were derived. Several SARs regarding nonsteroidal AR binding were revealed from the binding data, including stereoisomeric conformation, steric effect, and electronic effect. The functional activity of high-affinity ligands ranged from antagonist to full agonist for the AR. Several structural features were found to be determinative of agonist and antagonist activities. The nonsteroidal AR agonists identified from the present studies provided a pool of candidates for further development of selective androgen receptor modulators (SARMs) for androgen therapy. Also, these studies uncovered or confirmed numerous important SARs governing AR binding and functional properties by nonsteroidal molecules, which would be valuable in the future structural optimization of SARMs.

  14. Neuroticism in Young Women with Fibromyalgia Links to Key Clinical Features

    Directory of Open Access Journals (Sweden)

    Katrina Malin

    2012-01-01

    Full Text Available Objective. We examined personality traits in young women with FM, in order to seek associations with key psychological processes and clinical symptoms. Methods. Twenty-seven women with FM and 29 age-matched female healthy controls [HC] completed a series of questionnaires examining FM symptoms, personality and psychological variables. Results. Significant differences between characteristic FM symptoms (sleep, pain, fatigue, and confusion as well as for the psychological variables of depression, anxiety, and stress were found between FM and HC (P<0.001. Neuroticism was the only subscale of the Big Five Inventory that showed a significant difference between the FM group and HC group [P<0.05]. Within the FM group, there was a significant association between the level of the neuroticism and each of pain, sleep, fatigue, and confusion, depression, anxiety, and stress (P<0.05–0.01. The association between the level of neuroticism and the level of stress was the strongest of all variables tested (P<0.001. Conclusion. The personality trait of neuroticism significantly associates with the key FM characteristics of pain, sleep, fatigue and confusion as well as the common co-morbidities of depression, anxiety and stress. Personality appears to be an important modulator of FM clinical symptoms.

  15. CANDU with supercritical water coolant: conceptual design features

    International Nuclear Information System (INIS)

    Spinks, N.

    1997-01-01

    An advanced CANDU reactor, with supercritical water as coolant, has many attractive design features. The pressure exceeds 22 MPa but coolant temperatures in excess of 370 degrees C can be reached without encountering the two-phase region with its associated fuel-dry-out and flow-instability problems. Increased coolant temperature leads to increased plant thermodynamic efficiency reducing unit energy cost through reduced specific capital cost and reduced fueling cost. Increased coolant temperature leads to reduced void reactivity via reduced coolant in-core density. Light water becomes a coolant option. To preserve neutron economy, an advanced fuel channel is needed and is described below. A supercritical-water-cooled CANDU can evolve as fuel capabilities evolve to withstand increasing coolant temperatures. (author)

  16. The Progressive BSSG Rat Model of Parkinson's: Recapitulating Multiple Key Features of the Human Disease.

    Directory of Open Access Journals (Sweden)

    Jackalina M Van Kampen

    Full Text Available The development of effective neuroprotective therapies for Parkinson's disease (PD has been severely hindered by the notable lack of an appropriate animal model for preclinical screening. Indeed, most models currently available are either acute in nature or fail to recapitulate all characteristic features of the disease. Here, we present a novel progressive model of PD, with behavioural and cellular features that closely approximate those observed in patients. Chronic exposure to dietary phytosterol glucosides has been found to be neurotoxic. When fed to rats, β-sitosterol β-d-glucoside (BSSG triggers the progressive development of parkinsonism, with clinical signs and histopathology beginning to appear following cessation of exposure to the neurotoxic insult and continuing to develop over several months. Here, we characterize the progressive nature of this model, its non-motor features, the anatomical spread of synucleinopathy, and response to levodopa administration. In Sprague Dawley rats, chronic BSSG feeding for 4 months triggered the progressive development of a parkinsonian phenotype and pathological events that evolved slowly over time, with neuronal loss beginning only after toxin exposure was terminated. At approximately 3 months following initiation of BSSG exposure, animals displayed the early emergence of an olfactory deficit, in the absence of significant dopaminergic nigral cell loss or locomotor deficits. Locomotor deficits developed gradually over time, initially appearing as locomotor asymmetry and developing into akinesia/bradykinesia, which was reversed by levodopa treatment. Late-stage cognitive impairment was observed in the form of spatial working memory deficits, as assessed by the radial arm maze. In addition to the progressive loss of TH+ cells in the substantia nigra, the appearance of proteinase K-resistant intracellular α-synuclein aggregates was also observed to develop progressively, appearing first in the

  17. The emergent demand chain management: key features and illustration from the beef business

    NARCIS (Netherlands)

    Canever, M.D.; Trijp, van J.C.M.; Beers, G.

    2008-01-01

    Abstract Purpose - The paper seeks to delineate the emergence of demand chain management (DCM) from a theoretical perspective and to illustrate its occurrence in practice. Design/methodology/approach ¿ The DCM concept is examined empirically through a case study with retailers involved in the beef

  18. Good the bad and the ugly: perception as a key feature in road safety

    CSIR Research Space (South Africa)

    Venter, Karien

    2009-07-01

    Full Text Available psycho-social and behavioural context. Only when root causes are understood can the information be used to inform, design and implement the use of “visible” approaches, such as traffic calming, enforcement strategies and education or mass media campaigns....

  19. Housing Stakeholder Preferences for the "Soft" Features of Sustainable and Healthy Housing Design in the UK.

    Science.gov (United States)

    Prochorskaite, Agne; Couch, Chris; Malys, Naglis; Maliene, Vida

    2016-01-07

    It is widely recognised that the quantity and sustainability of new homes in the UK need to increase. However, it is important that sustainable housing is regarded holistically, and not merely in environmental terms, and incorporates elements that enhance the quality of life, health and well-being of its users. This paper focuses on the "soft" features of sustainable housing, that is, the non-technological components of sustainable housing and neighbourhood design that can impact occupants' health and well-being. Aims of the study are to ascertain the relative level of importance that key housing stakeholders attach to these features and to investigate whether the opinions of housing users and housing providers are aligned with regards to their importance. An online survey was carried out to gauge the level of importance that the key stakeholders, such as housing users, local authorities, housing associations, and developers (n = 235), attach to these features. Results revealed that while suitable indoor space was the feature regarded as most important by all stakeholders, there were also a number of disparities in opinion between housing users and housing providers (and among the different types of providers). This implies a scope for initiatives to achieve a better alignment between housing users and providers.

  20. Interactive Spacecraft Trajectory Design Strategies Featuring Poincare Map Topology

    Science.gov (United States)

    Schlei, Wayne R.

    Space exploration efforts are shifting towards inexpensive and more agile vehicles. Versatility regarding spacecraft trajectories refers to the agility to correct deviations from an intended path or even the ability to adapt the future path to a new destination--all with limited spaceflight resources (i.e., small DeltaV budgets). Trajectory design methods for such nimble vehicles incorporate equally versatile procedures that allow for rapid and interactive decision making while attempting to reduce Delta V budgets, leading to a versatile trajectory design platform. A versatile design paradigm requires the exploitation of Poincare map topology , or the interconnected web of dynamical structures, existing within the chaotic dynamics of multi-body gravitational models to outline low-Delta V transfer options residing nearby to a current path. This investigation details an autonomous procedure to extract the periodic orbits (topology nodes) and correlated asymptotic flow structures (or the invariant manifolds representing topology links). The autonomous process summarized in this investigation (termed PMATE) overcomes discontinuities on the Poincare section that arise in the applied multi-body model (the planar circular restricted three-body problem) and detects a wide variety of novel periodic orbits. New interactive capabilities deliver a visual analytics foundation for versatile spaceflight design, especially for initial guess generation and manipulation. Such interactive strategies include the selection of states and arcs from Poincare section visualizations and the capabilities to draw and drag trajectories to remove dependency on initial state input. Furthermore, immersive selection is expanded to cull invariant manifold structures, yielding low-DeltaV or even DeltaV-free transfers between periodic orbits. The application of interactive design strategies featuring a dense extraction of Poincare map topology is demonstrated for agile spaceflight with a simple

  1. Design features of the KSTAR in-vessel control coils

    Energy Technology Data Exchange (ETDEWEB)

    Kim, H.K. [National Fusion Research Institute (NFRI), 52 Yeoeun-dong, Yusung-ku, Daejeon, 305-333 (Korea, Republic of)], E-mail: hkkim@nfri.re.kr; Yang, H.L.; Kim, G.H.; Kim, Jin-Yong; Jhang, Hogun; Bak, J.S.; Lee, G.S. [National Fusion Research Institute (NFRI), 52 Yeoeun-dong, Yusung-ku, Daejeon, 305-333 (Korea, Republic of)

    2009-06-15

    In-vessel control coils (IVCCs) are to be used for the fast plasma position control, field error correction (FEC), and resistive wall mode (RWM) stabilization for the Korea Superconducting Tokamak Advanced Research (KSTAR) device. The IVCC system comprises 16 segments to be unified into a single set to achieve following remarkable engineering advantages; (1) enhancement of the coil system reliability with no welding or brazing works inside the vacuum vessel, (2) simplification in fabrication and installation owing to coils being fabricated outside the vacuum vessel and installed after device assembly, and (3) easy repair and maintenance of the coil system. Each segment is designed in 8 turns coil of 32 mm x 15 mm rectangular oxygen free high conductive copper with a 7 mm diameter internal coolant hole. The conductors are enclosed in 2 mm thick Inconel 625 rectangular welded vacuum jacket with epoxy/glass insulation. Structural analyses were implemented to evaluate structural safety against electromagnetic loads acting on the IVCC for the various operation scenarios using finite element analysis. This paper describes the design features and structural analysis results of the KSTAR in-vessel control coils.

  2. Improved safety features in the design of Alto Lazio NPP

    International Nuclear Information System (INIS)

    Bava, G.; Cianciolo, T.; Del Nero, G.

    1988-01-01

    The ALTO LAZIO Nuclear Power Plant, two 1000Mwe units, is a BWR 6/MARK III located about 100 km north of Rome, on the Tyrrhenian Sea Coasts. The construction of the plant started in 1978, but it has recently been stopped by a Government decision following a national referendum, when the units were about 70% completed. This paper is mainly intended to illustrate the major safety features which have been implemented as result of specific requirements issued by the safety authority (ENEA DISP) during the construction permit stage or the subsequent licensing process. One of the tools used to identify the need for design modifications has been a comprehensive reliability analysis of safety system: in the paper the methods used and the major results obtained by this study are briefly presented. Also, the approach used in the investigation of severe accidents and major applications in the area of plant design and emergency procedures are briefly discussed; furthermore the trend toward a simpler mitigation concept is described

  3. E-referral Solutions: Successful Experiences, Key Features and Challenges- a Systematic Review.

    Science.gov (United States)

    Naseriasl, Mansour; Adham, Davoud; Janati, Ali

    2015-06-01

    around the world health systems constantly face increasing pressures which arise from many factors, such as an ageing population, patients and providers demands for equipment's and services. In order to respond these challenges and reduction of health system's transactional costs, referral solutions are considered as a key factor. This study was carried out to identify referral solutions that have had successes. relevant studies identified using keywords of referrals, consultation, referral system, referral model, referral project, electronic referral, electronic booking, health system, healthcare, health service and medical care. These searches were conducted using PubMed, ProQuest, Google Scholar, Scopus, Emerald, Web of Knowledge, Springer, Science direct, Mosby's index, SID, Medlib and Iran Doc data bases. 4306 initial articles were obtained and refined step by step. Finally, 27 articles met the inclusion criteria. we identified seventeen e-referral systems developed in UK, Norway, Finland, Netherlands, Denmark, Scotland, New Zealand, Canada, Australia, and U.S. Implemented solutions had variant degrees of successes such as improved access to specialist care, reduced wait times, timeliness and quality of referral communication, accurate health information transfer and integration of health centers and services. each one of referral solutions has both positive and changeable aspects that should be addressed according to sociotechnical conditions. These solutions are mainly formed in a small and localized manner.

  4. Charge Segregation and Low Hydrophobicity Are Key Features of Ribosomal Proteins from Different Organisms*

    Science.gov (United States)

    Fedyukina, Daria V.; Jennaro, Theodore S.; Cavagnero, Silvia

    2014-01-01

    Ribosomes are large and highly charged macromolecular complexes consisting of RNA and proteins. Here, we address the electrostatic and nonpolar properties of ribosomal proteins that are important for ribosome assembly and interaction with other cellular components and may influence protein folding on the ribosome. We examined 50 S ribosomal subunits from 10 species and found a clear distinction between the net charge of ribosomal proteins from halophilic and non-halophilic organisms. We found that ∼67% ribosomal proteins from halophiles are negatively charged, whereas only up to ∼15% of ribosomal proteins from non-halophiles share this property. Conversely, hydrophobicity tends to be lower for ribosomal proteins from halophiles than for the corresponding proteins from non-halophiles. Importantly, the surface electrostatic potential of ribosomal proteins from all organisms, especially halophiles, has distinct positive and negative regions across all the examined species. Positively and negatively charged residues of ribosomal proteins tend to be clustered in buried and solvent-exposed regions, respectively. Hence, the majority of ribosomal proteins is characterized by a significant degree of intramolecular charge segregation, regardless of the organism of origin. This key property enables the ribosome to accommodate proteins within its complex scaffold regardless of their overall net charge. PMID:24398678

  5. KEY FEATURES OF THE INTRAGRAFT MICROENVIRONMENT THAT DETERMINE LONG-TERM SURVIVAL FOLLOWING TRANSPLANTATION

    Directory of Open Access Journals (Sweden)

    Sarah eBruneau

    2012-04-01

    Full Text Available In this review, we discuss how changes in the intragraft microenvironment serve to promote or sustain the development of chronic allograft rejection. We propose two key elements within the microenvironment that contribute to the rejection process. The first is endothelial cell proliferation and angiogenesis that serve to create abnormal microvascular blood flow patterns as well as local tissue hypoxia, and precedes endothelial-to-mesenchymal transition (EndMT. The second is the overexpression of local cytokines and growth factors that serve to sustain inflammation and, in turn, function to promote a leukocyte-induced angiogenesis reaction. Central to both events is overexpression of vascular endothelial growth factor (VEGF, which is both pro-inflammatory and pro-angiogenic, and thus drives progression of the chronic rejection microenvironment. In our discussion, we focus on how inflammation results in angiogenesis and how leukocyte-induced angiogenesis is pathological. We also discuss how VEGF is a master control factor that fosters the development of the chronic rejection microenvironment. Overall, this review provides insight into the intragraft microenvironment as an important paradigm for future direction in the field.

  6. Key Features of the Intragraft Microenvironment that Determine Long-Term Survival Following Transplantation

    Science.gov (United States)

    Bruneau, Sarah; Woda, Craig Bryan; Daly, Kevin Patrick; Boneschansker, Leonard; Jain, Namrata Gargee; Kochupurakkal, Nora; Contreras, Alan Gabriel; Seto, Tatsuichiro; Briscoe, David Michael

    2012-01-01

    In this review, we discuss how changes in the intragraft microenvironment serve to promote or sustain the development of chronic allograft rejection. We propose two key elements within the microenvironment that contribute to the rejection process. The first is endothelial cell proliferation and angiogenesis that serve to create abnormal microvascular blood flow patterns as well as local tissue hypoxia, and precedes endothelial-to-mesenchymal transition. The second is the overexpression of local cytokines and growth factors that serve to sustain inflammation and, in turn, function to promote a leukocyte-induced angiogenesis reaction. Central to both events is overexpression of vascular endothelial growth factor (VEGF), which is both pro-inflammatory and pro-angiogenic, and thus drives progression of the chronic rejection microenvironment. In our discussion, we focus on how inflammation results in angiogenesis and how leukocyte-induced angiogenesis is pathological. We also discuss how VEGF is a master control factor that fosters the development of the chronic rejection microenvironment. Overall, this review provides insight into the intragraft microenvironment as an important paradigm for future direction in the field. PMID:22566935

  7. DESIGNING FEATURES OF POWER OPTICAL UNITS FOR TECHNOLOGICAL EQUIPMENT

    Directory of Open Access Journals (Sweden)

    M. Y. Afanasiev

    2016-03-01

    Full Text Available This paper considers the question of an optical unit designing for transmitting power laser radiation through an optical fiber. The aim of this work is designing a simple construction unit with minimized reflection losses. The source of radiation in the optical unit described below is an ultraviolet laser with diode pumping. We present the general functioning scheme and designing features for the three main parts: laser beam deflecting system, laser beam dump and optical unit control system. The described laser beam deflection system is composed of a moving flat mirror and a spherical scattering mirror. Comparative analysis of the production technology for such mirrors was carried out, and, as a result, the decision was made to produce both mirrors of 99.99 % pure molybdenum without coating. A moving mirror deflects laser emission from a source through a fiber or deflects it on a spherical mirror and into the laser beam dump, moreover, switching from one position to another occurs almost immediately. It is shown that a scattering mirror is necessary, otherwise, the absorbing surface of the beam dump is being worn out irregularly. The laser beam dump is an open conical cavity, in which the conical element with its spire turned to the emission source is placed. Special microgeometry of the internal surface of the beam dump is suggested for the better absorption effect. An optical unit control system consists of a laser beam deflection system, laser temperature sensor, deflection system solenoid temperature sensor, and deflection mirror position sensor. The signal processing algorithm for signals coming from the sensors to the controller is described. The optical unit will be used in special technological equipment.

  8. An Axiomatic Design Approach of Nanofluid-Engineered Nuclear Safety Features for Generation III+ React

    International Nuclear Information System (INIS)

    Bang, In Cheol; Heo, Gyun Young; Jeong, Yong Hoon; Heo, Sun

    2009-01-01

    A variety of Generation III/III+ reactor designs featuring enhanced safety and improved economics are being proposed by nuclear power industries around the world to solve the future energy supply shortfall. Nanofluid coolants showing an improved thermal performance are being considered as a new key technology to secure nuclear safety and economics. However, it should be noted that there is a lack of comprehensible design works to apply nanofluids to Generation III+ reactor designs. In this work, the review of accident scenarios that consider expected nanofluid mechanisms is carried out to seek detailed application spots. The Axiomatic Design (AD) theory is then applied to systemize the design of nanofluid-engineered nuclear safety systems such as Emergency Core Cooling System (ECCS) and External Reactor Vessel Cooling System (ERVCS). The various couplings between Gen-III/III+ nuclear safety features and nanofluids are investigated and they try to be reduced from the perspective of the AD in terms of prevention/mitigation of severe accidents. This study contributes to the establishment of a standard communication protocol in the design of nanofluid-engineered nuclear safety systems

  9. Origin and spread of photosynthesis based upon conserved sequence features in key bacteriochlorophyll biosynthesis proteins.

    Science.gov (United States)

    Gupta, Radhey S

    2012-11-01

    The origin of photosynthesis and how this capability has spread to other bacterial phyla remain important unresolved questions. I describe here a number of conserved signature indels (CSIs) in key proteins involved in bacteriochlorophyll (Bchl) biosynthesis that provide important insights in these regards. The proteins BchL and BchX, which are essential for Bchl biosynthesis, are derived by gene duplication in a common ancestor of all phototrophs. More ancient gene duplication gave rise to the BchX-BchL proteins and the NifH protein of the nitrogenase complex. The sequence alignment of NifH-BchX-BchL proteins contain two CSIs that are uniquely shared by all NifH and BchX homologs, but not by any BchL homologs. These CSIs and phylogenetic analysis of NifH-BchX-BchL protein sequences strongly suggest that the BchX homologs are ancestral to BchL and that the Bchl-based anoxygenic photosynthesis originated prior to the chlorophyll (Chl)-based photosynthesis in cyanobacteria. Another CSI in the BchX-BchL sequence alignment that is uniquely shared by all BchX homologs and the BchL sequences from Heliobacteriaceae, but absent in all other BchL homologs, suggests that the BchL homologs from Heliobacteriaceae are primitive in comparison to all other photosynthetic lineages. Several other identified CSIs in the BchN homologs are commonly shared by all proteobacterial homologs and a clade consisting of the marine unicellular Cyanobacteria (Clade C). These CSIs in conjunction with the results of phylogenetic analyses and pair-wise sequence similarity on the BchL, BchN, and BchB proteins, where the homologs from Clade C Cyanobacteria and Proteobacteria exhibited close relationship, provide strong evidence that these two groups have incurred lateral gene transfers. Additionally, phylogenetic analyses and several CSIs in the BchL-N-B proteins that are uniquely shared by all Chlorobi and Chloroflexi homologs provide evidence that the genes for these proteins have also been

  10. Lobbying and Social Participation – Key Features for an Effective Public Administration in Romania

    Directory of Open Access Journals (Sweden)

    Laura Maria IRIMIEȘ

    2017-12-01

    Full Text Available Lobbying is one of the main structural elements of democratic governance and sustainable development and is essential to achieving competitive and effi cient administrative and decisional processes in local governance. Successfully implementing lobbying regulations and techniques is of extreme importance for any public system, where social participation in the decision-making process can strongly contribute to social, political and economic / fi nancial effi - ciency. Over the last 15 years, several legislative initiatives have tried to design a coherent framework for lobby, but they are still unapplied either due to insuffi cient public understanding of the concept, or due to more or less justifi ed uncertainties and fears. The necessity of regulating lobbying in Romania is placed in a context where an important number of anticorruption international and domestic recommendations and state reliability statistics, added to a certain lack of effectiveness in time and public money management, show that the public administration system needs to be reformed. And lobbying is, as the following article shows, a must for any public reform of public administration in Romania. The case of multilingual entrance signs / labels in Cluj-Napoca is an unquestionable and unbeatable example that the simple existence of legal frameworks of lobbying could turn into real time, energy and money savers.

  11. Dhruva: Main design features, operational experience and utilization

    Energy Technology Data Exchange (ETDEWEB)

    Agarwal, S.K. [Reactor Group, BARC, Trombay, Mumbai 400085 (India)]. E-mail: swarajagarwal2000@yahoo.com; Karhadkar, C.G. [Reactor Group, BARC, Trombay, Mumbai 400085 (India); Zope, A.K. [Reactor Group, BARC, Trombay, Mumbai 400085 (India); Singh, Kanchhi [Reactor Group, BARC, Trombay, Mumbai 400085 (India)

    2006-04-15

    Dhruva is a product of technological initiatives taken during mid seventies when a need was felt for another research reactor having a high neutron flux to meet the growing demands of research and development in the frontier areas of science and engineering. In addition production of radioisotopes of high specific activity and the diverse requirements of a broad based user community had to be synthesized into a viable system, which could be engineered within the limited means available in the country. This high neutron flux reactor was designed, constructed and commissioned entirely by Indian scientists and engineers and it reflects the country's resolve to achieve self-reliance in the nuclear reactor technology. Dhruva is a 100 MW (thermal) research reactor with metallic natural uranium as fuel, heavy water as moderator, coolant and reflector, giving a maximum thermal neutron flux of 1.8 x 10{sup 14} n/cm{sup 2}/s. Since its first criticality on 8th August 1985, a number of experimental facilities have been added which have proven to be highly attractive for universities and industrial researchers for their scientific merits in various fields. One of the major utilization areas has been the neutron beam research using several neutron spectrometers, all of which were built in-house. A guide tube facility comprising of two neutron guides and another experimental set-up with a multi-instrument beam line have enabled further enhancement of the utilization of this National Facility by the academic institutions in the country. Production of radioisotopes of high specific activity and in increased quantity has fulfilled growing demands for many applications. The write-up provides an overview of the reactor covering its design; layout, safety features, utilization and operating experience along with description of some of the specific experimental facilities.

  12. SCW Pressure-Channel Nuclear Reactor Some Design Features

    Science.gov (United States)

    Pioro, Igor L.; Khan, Mosin; Hopps, Victory; Jacobs, Chris; Patkunam, Ruban; Gopaul, Sandeep; Bakan, Kurtulus

    Concepts of nuclear reactors cooled with water at supercritical pressures were studied as early as the 1950s and 1960s in the USA and Russia. After a 30-year break, the idea of developing nuclear reactors cooled with SuperCritical Water (SCW) became attractive again as the ultimate development path for water cooling. The main objectives of using SCW in nuclear reactors are: 1) to increase the thermal efficiency of modern Nuclear Power Plants (NPPs) from 30-35% to about 45-48%, and 2) to decrease capital and operational costs and hence decrease electrical energy costs (˜1000 US/kW or even less). SCW NPPs will have much higher operating parameters compared to modern NPPs (pressure about 25 MPa and outlet temperature up to 625°C), and a simplified flow circuit, in which steam generators, steam dryers, steam separators, etc., can be eliminated. Also, higher SCW temperatures allow direct thermo-chemical production of hydrogen at low cost, due to increased reaction rates. Pressure-tube or pressure-channel SCW nuclear reactor concepts are being developed in Canada and Russia for some time. Some design features of the Canadian concept related to fuel channels are discussed in this paper. The main conclusion is that the development of SCW pressure-tube nuclear reactors is feasible and significant benefits can be expected over other thermal-energy systems.

  13. Key developments in the advanced NPP with WWER-640/V-407 reactor plant design

    International Nuclear Information System (INIS)

    Dragunov, Yu.G.; Mokhov, V.A.; Nikitenko, M.P.; Afrov, A.M.

    1999-01-01

    The report covers the main design features of advanced NPP equipped with WWER-640 reactor, that take into account the up-to-date approaches in the process of forming safety concepts. An approach to accident management has been analysed, beyond design-basis accidents included. A description of principal safety systems has been presented as well as the interrelation of their operation. The principal features of the systems design have been shown. (author)

  14. Engineering design of the IFMIF EVEDA reference test cell and key components

    Energy Technology Data Exchange (ETDEWEB)

    Tian, Kuo, E-mail: kuo.tian@kit.edu [Institute for Neutron Physics and Reactor Technology, Karlsruhe Institute of Technology, Karlsruhe (Germany); Arbeiter, Frederik; Chen, Yuming; Heinzel, Volker; Kondo, Keitaro [Institute for Neutron Physics and Reactor Technology, Karlsruhe Institute of Technology, Karlsruhe (Germany); Mittwollen, Martin [Institute for Material Handling and Logistics, Karlsruhe Institute of Technology, Karlsruhe (Germany)

    2014-10-15

    The latest design updates of the IFMIF-EVEDA reference test cell (TC) are described with emphasis on the following key components: active cooling pipes for concrete biological shielding walls and stainless steel liner, TC gas leak tight boundary, and piping and cabling inside TC and between TC and the access cell (AC). Water cooling is adopted for concrete shielding walls and the liner. Buried pipes are selected for active cooling of the TC surrounding shielding walls; directly welded pipes on the liner are used to remove nuclear heat of the liner. Technical features and layout of the cooling pipes are preliminary defined. The TC vacuum boundary, which includes the TC liner, an independent TC cover plate, a rubber based sealing gasket, and welding seams between interface shielding plugs and TC liner, is described. Engineering design of the piping and cabling plugs as well as the arrangement of pipes and cables under the TC covering plate and the AC floor are updated. Pipes and cable tunnels inside the shielding plugs are arranged with several bends for minimizing neutron streaming from inside to outside of the TC. Pipes, cables, and the corresponding penetrations between the TC and the AC are carefully arranged for convenient access and maintenances.

  15. Soft sensor design by multivariate fusion of image features and process measurements

    DEFF Research Database (Denmark)

    Lin, Bao; Jørgensen, Sten Bay

    2011-01-01

    This paper presents a multivariate data fusion procedure for design of dynamic soft sensors where suitably selected image features are combined with traditional process measurements to enhance the performance of data-driven soft sensors. A key issue of fusing multiple sensor data, i.e. to determine...... with a multivariate analysis technique from RGB pictures. The color information is also transformed to hue, saturation and intensity components. Both sets of image features are combined with traditional process measurements to obtain an inferential model by partial least squares (PLS) regression. A dynamic PLS model...... oxides (NOx) emission of cement kilns. On-site tests demonstrate improved performance over soft sensors based on conventional process measurements only....

  16. Key engineering features of the ITER-FEAT magnet system and implications for the R and D programme

    International Nuclear Information System (INIS)

    Huguet, M.

    2001-01-01

    The magnet design of the new ITER-FEAT machine comprises 18 Toroidal Field (TF) coils, a Central Solenoid (CS), 6 Poloidal Field (PF) coils and Correction Coils (CCs). A key driver of this new design is the requirement to generate and control plasmas with a relatively high elongation (k 95 =1.7) and a relatively high triangularity (δ 95 =0.35). This has lead to a design where the CS is vertically segmented and self-standing and the TF coils are wedged along their inboard legs. Another important design driver is to achieve a high operational reliability of the magnets, and this has resulted in several unconventional designs, and in particular, the use of conductors supported in radial plates for the winding pack of the TF coils. A key mechanical issue is the cyclic loading of the TF coil cases due to the out-of-plane loads which result from the interaction of the TF coil current and the poloidal field. These loads are resisted by a combination of shear keys and 'pre-compression' rings able to provide a centripetal preload at assembly. The fatigue life of the CS conductor jacket is another issue as it determines the CS performance in terms of the flux generation. Two jacket materials and designs are under study. Since 1993, the ITER magnet R and D programme has been focussed on the manufacture and testing of a CS and a TF model coil. During its testing, the CS model coil has successfully achieved all its performance targets in DC and AC operations. The manufacture of the TF model coil is complete. The manufacture of segments of the full scale TF coil case is another important and successful part of this programme and is near completion. New R and D effort is now being initiated to cover specific aspects of the ITER-FEAT design. (author)

  17. Key Design Characteristics for Developing Usable E-Commerce Websites in the Arab World

    Directory of Open Access Journals (Sweden)

    Layla Hasan

    2016-09-01

    Full Text Available This research aims to suggest key design characteristics that are necessary for developing usable e-commerce websites in the Arab world. A comprehensive usability evaluation of four leading Arab e-commerce websites was conducted using the heuristic evaluation method. The results identified major and minor usability problems and major and minor good design characteristics on the selected websites. Based on the results, 51 key design characteristics were suggested. The recommended key design characteristics comprised two levels according to their priority: level one which includes mandatory key design characteristics and level two which includes supplementary design characteristics. The key design characteristics in each level were categorized under specific pages and areas that can be found on any e-commerce website. Such categorizations could direct website evaluators and designers to important pages and areas that should be considered to improve the overall usability of e-commerce websites. The results of this research are particularly important to developing countries which are still facing challenges that may affect the design and accessibility of usable and useful websites. These relate to low speed of accessing the Internet and a lack of website designers who have experience in customers’ needs and websites’ usable design characteristics.

  18. Main design and safety features of a 200MW nuclear heating reactor

    International Nuclear Information System (INIS)

    Zheng, Wenxiang; Gao, Zuying; Wang, Dazhong

    1992-01-01

    Inept has been in charge of the development of a nuclear heating reactor since 1980s, which is one of the national key R and D Programs in China. A 5MWt experimental NCR was completed at Inept in 1989 and has operated successfully for space heating since then. In order to realize the commercialization of the NCR, it has been decided to construct a 200MW demonstration NCR in 1993. A number of advanced features, including natural circulation, integrated arrangement, self-pressurized performance, dual vessel structure, hydraulic control rod drive and passive safety systems, have been incorporated into the NCR-200 to achieve its safety goal and economic viability. This makes the NCR safe, simple, reliable, easy-constructed and maintained. At present, the design work of the NCR-200 have shown that its safety characteristics are excellent. The NCR could play an important role in resolving future energy and environmental problems in China. The paper will mainly cover the key design considerations, main technical features and safety analysis results of the NCR-200

  19. Key features of human episodic recollection in the cross-episode retrieval of rat hippocampus representations of space.

    Directory of Open Access Journals (Sweden)

    Eduard Kelemen

    2013-07-01

    Full Text Available Neurophysiological studies focus on memory retrieval as a reproduction of what was experienced and have established that neural discharge is replayed to express memory. However, cognitive psychology has established that recollection is not a verbatim replay of stored information. Recollection is constructive, the product of memory retrieval cues, the information stored in memory, and the subject's state of mind. We discovered key features of constructive recollection embedded in the rat CA1 ensemble discharge during an active avoidance task. Rats learned two task variants, one with the arena stable, the other with it rotating; each variant defined a distinct behavioral episode. During the rotating episode, the ensemble discharge of CA1 principal neurons was dynamically organized to concurrently represent space in two distinct codes. The code for spatial reference frame switched rapidly between representing the rat's current location in either the stationary spatial frame of the room or the rotating frame of the arena. The code for task variant switched less frequently between a representation of the current rotating episode and the stable episode from the rat's past. The characteristics and interplay of these two hippocampal codes revealed three key properties of constructive recollection. (1 Although the ensemble representations of the stable and rotating episodes were distinct, ensemble discharge during rotation occasionally resembled the stable condition, demonstrating cross-episode retrieval of the representation of the remote, stable episode. (2 This cross-episode retrieval at the level of the code for task variant was more likely when the rotating arena was about to match its orientation in the stable episode. (3 The likelihood of cross-episode retrieval was influenced by preretrieval information that was signaled at the level of the code for spatial reference frame. Thus key features of episodic recollection manifest in rat hippocampal

  20. Left ventricular assist device (lvad design features: literature review

    Directory of Open Access Journals (Sweden)

    Yu. V. Bogdanova

    2014-01-01

    long-term systems of artificial circulatory support is guided by German Heart Center in Berlin (DHZB [3].The well-known VAD commercial models were created by Berlin Heart (Germany, HeartWare Int. (USA, Thoratec (USA, Abiomed Inc. (USA etc.Works devoted to VAD systems can be classified in field of research, according to the above subsystems. Concerning the blood pump - a large number of works is devoted to the study of blood behavior in the pump chamber: to modeling questions [6-24], with an emphasis on red blood cells damage - hemolysis [10, 20, 23, 27-32]. Much less works are devoted to the research of rotor (impeller dynamics of the blood pump [33-36]. Application of magnetic bearings in VAD and magnetic levitation control tasks of are addressed in [33-39]. Biomedical part of design, associated with the selection and development of biocompatible materials is considered in [26, 32, 40-43]. Features of power supply systems and control of VAD mode work are given in works [26, 44-50].The integrated approach to VAD development with an emphasis on design phases is presented in the works [7, 51]. In [2] the problem of artificial heart creation in Russia on 2006 is clearly reflected. The most comprehensive systematic review of existing VAD systems with description of specifications is given in the work [54], as well as in [24, 26, 55-57]. Brief review of existing methodologies and approaches to the design of artificial heart (AH and circulatory support system (CSS are presented in the works [58, 59]. The problem of creation of mechatronic modules of AH and CSS systems is studied in [60, 61].With the purpose of further research in the development of VAD system, this work is the study of up to date problem state. The main part of the work consists of three sections. The first section is devoted to the study of blood pump. The second and the third sections are devoted to power supply system and control system respectively. Based on this analysis, the requirements to VAD

  1. Work plan for special design features and crack sealing maintenance.

    Science.gov (United States)

    2013-09-01

    The Alaska DOT&PF wants to construct and maintain asphalt concrete (AC) paved highways in a way that minimizes roadway lifecycle costs while preserving acceptable : performance. Thermal cracking is a natural feature of most paved Alaska roadways that...

  2. Designing basin-customized combined drought indices via feature extraction

    Science.gov (United States)

    Zaniolo, Marta; Giuliani, Matteo; Castelletti, Andrea

    2017-04-01

    The socio-economic costs of drought are progressively increasing worldwide due to the undergoing alteration of hydro-meteorological regimes induced by climate change. Although drought management is largely studied in the literature, most of the traditional drought indexes fail in detecting critical events in highly regulated systems, which generally rely on ad-hoc formulations and cannot be generalized to different context. In this study, we contribute a novel framework for the design of a basin-customized drought index. This index represents a surrogate of the state of the basin and is computed by combining the available information about the water available in the system to reproduce a representative target variable for the drought condition of the basin (e.g., water deficit). To select the relevant variables and how to combine them, we use an advanced feature extraction algorithm called Wrapper for Quasi Equally Informative Subset Selection (W-QEISS). The W-QEISS algorithm relies on a multi-objective evolutionary algorithm to find Pareto-efficient subsets of variables by maximizing the wrapper accuracy, minimizing the number of selected variables (cardinality) and optimizing relevance and redundancy of the subset. The accuracy objective is evaluated trough the calibration of a pre-defined model (i.e., an extreme learning machine) of the water deficit for each candidate subset of variables, with the index selected from the resulting solutions identifying a suitable compromise between accuracy, cardinality, relevance, and redundancy. The proposed methodology is tested in the case study of Lake Como in northern Italy, a regulated lake mainly operated for irrigation supply to four downstream agricultural districts. In the absence of an institutional drought monitoring system, we constructed the combined index using all the hydrological variables from the existing monitoring system as well as the most common drought indicators at multiple time aggregations. The soil

  3. A Research Review on the Key Technologies of Intelligent Design for Customized Products

    Directory of Open Access Journals (Sweden)

    Shuyou Zhang

    2017-10-01

    Full Text Available The development of technologies such as big data and cyber-physical systems (CPSs has increased the demand for product design. Product digital design involves completing the product design process using advanced digital technologies such as geometry modeling, kinematic and dynamic simulation, multi-disciplinary coupling, virtual assembly, virtual reality (VR, multi-objective optimization (MOO, and human-computer interaction. The key technologies of intelligent design for customized products include: a description and analysis of customer requirements (CRs, product family design (PFD for the customer base, configuration and modular design for customized products, variant design for customized products, and a knowledge push for product intelligent design. The development trends in intelligent design for customized products include big-data-driven intelligent design technology for customized products and customized design tools and applications. The proposed method is verified by the design of precision computer numerical control (CNC machine tools.

  4. Do Particular Design Features Assist People with Aphasia to Comprehend Text? An Exploratory Study

    Science.gov (United States)

    Wilson, Lucy; Read, Jennifer

    2016-01-01

    Background: Much of the evidence underlying guidelines for producing accessible information for people with aphasia focuses on client preference for particular design features. There is limited evidence regarding the effects of these features on comprehension. Aims: To examine the effects of specific design features on text comprehension. It was…

  5. A VR-User Interface for Design by Features

    NARCIS (Netherlands)

    Coomans, M.K.D.; Timmermans, H.J.P.

    1998-01-01

    We present the design of a Virtual Reality based user interface (VR-UI). It is the interface for the VR-DIS system, a design application for the Building and Construction industry (VRDIS stands for Virtual Reality - Design Information System). The interface is characterised by a mixed representation

  6. The Design of High-Q Sallen-Key Biquads with Unity-Gain Buffer Amplifiers

    DEFF Research Database (Denmark)

    Gaunholt, Hans; Guldbrandsen, Birthe

    1997-01-01

    In the design of active biquads with negative feedback frequently referred to as Sallen-Key networks the assumption of a low quality- or Q-factor is recommended in order to keep the active sensitivities at a reasonable low value. In this paper it will be shown that it is possible to design and to...

  7. The Design Co-ordination Framework: key elements for effective product development

    DEFF Research Database (Denmark)

    Andreasen, Mogens Myrup; Bowen, J.; Storm, T.

    1997-01-01

    This paper proposes a Design Co-ordination Framework (DCF) i.e. a concept for an ideal DC system with the abilities to support co-ordination of various complex aspects of product development. A set of frames, modelling key elements of co-ordination, which reflect the states of design, plans, orga...

  8. License Application Design Selection Feature Report Canistered Assemblies

    International Nuclear Information System (INIS)

    Bennett, Scott M.

    1999-01-01

    The objective of the Modified Waste Emplacement Mode Design Alternative Report is to identify, describe, and evaluate waste package emplacement modes against a specified set of evaluation criteria. This evaluation of the design alternative will be used as input to the decision-making process used to identify the EDAs. The EDAs will, in turn, be evaluated against a set of evaluation criteria, and their evaluations will be used as the basis for an M and O recommendation on the LA design

  9. Design features of the SSC [Superconducting Super Collider] dipole magnet

    International Nuclear Information System (INIS)

    Willen, E.; Cottingham, J.; Ganetis, G.

    1989-01-01

    The main ring dipole for the SSC is specified as a high performance magnet that is required to provide a uniform, 6.6 T field in a 4 cm aperture at minimum cost. These design requirements have been addressed in an R ampersand D program in which the coil design, coil mechanical support, yoke and shell structure, trim coil and beam tube design, and a variety of new instrumentation, have been developed. The design of the magnet resulting from this intensive R ampersand D program, including various measurements from both 1.8 m and 17 m long models, is reviewed. 7 refs., 3 figs

  10. Unique features of creative designing at the preschool age

    Directory of Open Access Journals (Sweden)

    Bilа Iryna Mykolayivna

    2017-04-01

    Full Text Available The research is devoted to studying the specificity of creative designing at the preschool age. The author identifies the systematic approach on the design work and creative designing, knowledge adjustment, as well as the assessment criteria and performance indicators of creative designing by children at the preschool age. The article considers the psychological structure of the design activity, clarifies its characteristics and defines the role of each component of creative designing process at the preschool age. As a result of the empirical study it was proved that in the process of understanding the challenges pre-schoolers’s mind makes mental acts of comparison predominant. Their creative intention is determined by the focus on the structural and structural-functional characteristics of the subjects. The whole structure of the pre-schooler’s solution in the process of working with creative tasks on designing is integrated with the individual and regulatory aspect of creative designing that appears in the subjective mental actions, trends, and practice.

  11. The Alternative Design Features for Safety Enhancement in Shutdown Operation

    International Nuclear Information System (INIS)

    Oh, Hae Cheol; Kim, Myung Ki; Chung, Bag Soon; Seo, Mi Ro

    2009-01-01

    PSA can be used to confirm that the new plant design is complied with the applicable safety goals, and to select among the alternate design options. A shutdown PSA provides insight for outage planning schedule, outage management practices, and design modifications. Considering the results of both LPSD PSA studies and operating experiences for low power and shutdown, the improvements can be proposed to reduce the high risk contribution. The improvements/enhancements during shutdown operation may be divided into categories such as hardware, administrative management, and operational procedure. This paper presents on an example how the risk related to an accidental situation can be reduced, focusing the hardware design changes for the newly designed NPPs

  12. Automated Feature Design for Time Series Classification by Genetic Programming

    OpenAIRE

    Harvey, Dustin Yewell

    2014-01-01

    Time series classification (TSC) methods discover and exploit patterns in time series and other one-dimensional signals. Although many accurate, robust classifiers exist for multivariate feature sets, general approaches are needed to extend machine learning techniques to make use of signal inputs. Numerous applications of TSC can be found in structural engineering, especially in the areas of structural health monitoring and non-destructive evaluation. Additionally, the fields of process contr...

  13. Key features for more successful place-based sustainability research on social-ecological systems: a Programme on Ecosystem Change and Society (PECS perspective

    Directory of Open Access Journals (Sweden)

    Patricia Balvanera

    2017-03-01

    Full Text Available The emerging discipline of sustainability science is focused explicitly on the dynamic interactions between nature and society and is committed to research that spans multiple scales and can support transitions toward greater sustainability. Because a growing body of place-based social-ecological sustainability research (PBSESR has emerged in recent decades, there is a growing need to understand better how to maximize the effectiveness of this work. The Programme on Ecosystem Change and Society (PECS provides a unique opportunity for synthesizing insights gained from this research community on key features that may contribute to the relative success of PBSESR. We surveyed the leaders of PECS-affiliated projects using a combination of open, closed, and semistructured questions to identify which features of a research project are perceived to contribute to successful research design and implementation. We assessed six types of research features: problem orientation, research team, and contextual, conceptual, methodological, and evaluative features. We examined the desirable and undesirable aspects of each feature, the enabling factors and obstacles associated with project implementation, and asked respondents to assess the performance of their own projects in relation to these features. Responses were obtained from 25 projects working in 42 social-ecological study cases within 25 countries. Factors that contribute to the overall success of PBSESR included: explicitly addressing integrated social-ecological systems; a focus on solution- and transformation-oriented research; adaptation of studies to their local context; trusted, long-term, and frequent engagement with stakeholders and partners; and an early definition of the purpose and scope of research. Factors that hindered the success of PBSESR included: the complexities inherent to social-ecological systems, the imposition of particular epistemologies and methods on the wider research group

  14. Design features and cost reduction potential of JSFR

    International Nuclear Information System (INIS)

    Katoh, Atsushi; Hayafune, Hiroki; Kotake, Shoji

    2014-01-01

    Highlights: • Japan Sodium Cooled Fast Reactor (JSFR) is designed to reduce plant commodity. • Cost reduction effectiveness by innovative designs is estimated by bottom up method. • JSFR achieves 76% construction cost reduction compared with Monju by design effort. • Commercial JSFR construction cost could be less than that of conventional LWR. - Abstract: To improve the economic competitiveness of the Japan Sodium-cooled Fast Reactor (JSFR), several innovative designs have been introduced, e.g. reduction of number of main cooling loop, shorter pipe arrangement by adopting thermally durable material, in fact high chromium ferrite steel, a compact reactor vessel (RV), integration of a primary pump and an intermediate heat exchanger (IHX). Since they had not been introduced in the past and existing reactors, a new approach for construction cost estimation has been introduced to handle innovative technologies, for example, concerning different kinds of material, fabrication processes of equipment etc. As results of JSFR construction cost estimations based on the new method and the latest conceptual JSFR design, economic goals of Generation IV nuclear energy systems can be achieved by expecting the following cost reduction effects: commodity reduction by adopting innovative design, an economy of scale by power generation increase, learning effect etc. It is well analyzed quantitatively that feasibility of innovative designs is essential for economic competitiveness of JSFR

  15. Design features and cost reduction potential of JSFR

    Energy Technology Data Exchange (ETDEWEB)

    Katoh, Atsushi, E-mail: kato.atsushi@jaea.go.jp [Japan Atomic Energy Agency, 4002 Narita, Oarai-machi, Higashi-ibaraki-gun, Ibaraki-ken 311-1393 (Japan); Hayafune, Hiroki [Japan Atomic Energy Agency, 4002 Narita, Oarai-machi, Higashi-ibaraki-gun, Ibaraki-ken 311-1393 (Japan); Kotake, Shoji [The Japan Atomic Power Company, 1-1 Kanda-midoricyo, Chiyoda-ku, Tokyo-to 101-0053 (Japan)

    2014-12-15

    Highlights: • Japan Sodium Cooled Fast Reactor (JSFR) is designed to reduce plant commodity. • Cost reduction effectiveness by innovative designs is estimated by bottom up method. • JSFR achieves 76% construction cost reduction compared with Monju by design effort. • Commercial JSFR construction cost could be less than that of conventional LWR. - Abstract: To improve the economic competitiveness of the Japan Sodium-cooled Fast Reactor (JSFR), several innovative designs have been introduced, e.g. reduction of number of main cooling loop, shorter pipe arrangement by adopting thermally durable material, in fact high chromium ferrite steel, a compact reactor vessel (RV), integration of a primary pump and an intermediate heat exchanger (IHX). Since they had not been introduced in the past and existing reactors, a new approach for construction cost estimation has been introduced to handle innovative technologies, for example, concerning different kinds of material, fabrication processes of equipment etc. As results of JSFR construction cost estimations based on the new method and the latest conceptual JSFR design, economic goals of Generation IV nuclear energy systems can be achieved by expecting the following cost reduction effects: commodity reduction by adopting innovative design, an economy of scale by power generation increase, learning effect etc. It is well analyzed quantitatively that feasibility of innovative designs is essential for economic competitiveness of JSFR.

  16. Audio Key Finding: Considerations in System Design and Case Studies on Chopin's 24 Preludes

    Directory of Open Access Journals (Sweden)

    Elaine Chew

    2007-01-01

    Full Text Available We systematically analyze audio key finding to determine factors important to system design, and the selection and evaluation of solutions. First, we present a basic system, fuzzy analysis spiral array center of effect generator algorithm, with three key determination policies: nearest-neighbor (NN, relative distance (RD, and average distance (AD. AD achieved a 79% accuracy rate in an evaluation on 410 classical pieces, more than 8% higher RD and NN. We show why audio key finding sometimes outperforms symbolic key finding. We next propose three extensions to the basic key finding system—the modified spiral array (mSA, fundamental frequency identification (F0, and post-weight balancing (PWB—to improve performance, with evaluations using Chopin's Preludes (Romantic repertoire was the most challenging. F0 provided the greatest improvement in the first 8 seconds, while mSA gave the best performance after 8 seconds. Case studies examine when all systems were correct, or all incorrect.

  17. Design of a fast runback feature for PRISM control

    International Nuclear Information System (INIS)

    Wagner, W.K.; Rhow, S.K.; Daniel, W.R.; Dayal, Y.; Gaubatz, D.C.

    1988-01-01

    The nine power reactor inherently safe modules (PRISM) are controlled and their operation coordinated by a hierarchical, distributed, digital plant control system (PCS). This paper describes the fast runback features of the PCS. Fast runback consists of PCS directed reactor module shutdown with accompanying reductions of coolant flows. Analyses have shown that the PCS fast runback adequately terminates duty cycle events initiated in the balance of plant and the steam generating system, results in lower thermal shock to the reactor than scram, and reduces the number of scrams by approximately a factor of five

  18. Enhancing Critical Infrastructure and Key Resources (CIKR) Level-0 Physical Process Security Using Field Device Distinct Native Attribute Features

    Energy Technology Data Exchange (ETDEWEB)

    Lopez, Juan [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Liefer, Nathan C. [Wright-Patterson AFB, Dayton, OH (United States); Busho, Colin R. [Wright-Patterson AFB, Dayton, OH (United States); Temple, Michael A. [Wright-Patterson AFB, Dayton, OH (United States)

    2017-12-04

    Here, the need for improved Critical Infrastructure and Key Resource (CIKR) security is unquestioned and there has been minimal emphasis on Level-0 (PHY Process) improvements. Wired Signal Distinct Native Attribute (WS-DNA) Fingerprinting is investigated here as a non-intrusive PHY-based security augmentation to support an envisioned layered security strategy. Results are based on experimental response collections from Highway Addressable Remote Transducer (HART) Differential Pressure Transmitter (DPT) devices from three manufacturers (Yokogawa, Honeywell, Endress+Hauer) installed in an automated process control system. Device discrimination is assessed using Time Domain (TD) and Slope-Based FSK (SB-FSK) fingerprints input to Multiple Discriminant Analysis, Maximum Likelihood (MDA/ML) and Random Forest (RndF) classifiers. For 12 different classes (two devices per manufacturer at two distinct set points), both classifiers performed reliably and achieved an arbitrary performance benchmark of average cross-class percent correct of %C > 90%. The least challenging cross-manufacturer results included near-perfect %C ≈ 100%, while the more challenging like-model (serial number) discrimination results included 90%< %C < 100%, with TD Fingerprinting marginally outperforming SB-FSK Fingerprinting; SB-FSK benefits from having less stringent response alignment and registration requirements. The RndF classifier was most beneficial and enabled reliable selection of dimensionally reduced fingerprint subsets that minimize data storage and computational requirements. The RndF selected feature sets contained 15% of the full-dimensional feature sets and only suffered a worst case %CΔ = 3% to 4% performance degradation.

  19. Diamonds in the rough: key performance indicators for reticles and design sets

    Science.gov (United States)

    Ackmann, Paul

    2008-10-01

    The discussion on reticle cost continues to raise questions by many in the semiconductor industry. The diamond industry developed a method to judge and grade diamonds. [1, 11] The diamond-marketing tool of "The 4Cs of Diamonds" and other slogans help explain the multiple, complex variables that determine the value of a particular stone. Understanding the critical factors of Carat, Clarity, Color, and Cut allows all customers to choose a gem that matches their unique desires. I apply the same principles of "The 4Cs of Diamonds" to develop an analogous method for rating and tracking reticle performance. I introduced the first 3Cs of reticle manufacturing during my BACUS presentation panel at SPIE in February 2008. [2] To these first 3Cs (Capital, Complexity, and Content), I now add a fourth, Cycle time. I will look at how our use of reticles changes by node and use "The 4Cs of Reticles" to develop the key performance indicators (KPI) that will help our industry set standards for evaluating reticle technology. Capital includes both cost and utilization. This includes tools, people, facilities, and support systems required for building the most critical reticles. Tools have highest value in the first two years of use, and each new technology node will likely increase the Capital cost of reticles. New technologies, specifications, and materials drive Complexity for reticles, including smaller feature size, increased optical proximity correction (OPC), and more levels at sub-wavelength. The large data files needed to create finer features require the use of the newest tools for writing, inspection, and repair. Content encompasses the customer's specifications and requirements, which the mask shop must meet. The specifications are critical because they drive wafer yield. A clear increase of the number of masking levels has occurred since the 90 nm node. Cycle time starts when the design is finished and lasts until the mask house ships the reticle to the fab. Depending on

  20. Diffusive Barrier and Getter Under Waste Packages VA Reference Design Feature Evaluations

    International Nuclear Information System (INIS)

    MacNeil, K.

    1999-01-01

    This technical document evaluates those aspects of the diffusive barrier and getter features which have the potential for enhancing the performance of the Viability Assessment Reference Design and are also directly related to the key attributes for the repository safety strategy of that design. The effects of advection, hydrodynamic dispersion, and diffusion on the radionuclide migration rates through the diffusive barrier were determined through the application of the one-dimensional, advection/dispersion/diffusion equation. The results showed that because advective flow described by the advection-dispersion equation dominates, the diffusive barrier feature alone would not be effective in retarding migration of radiocuclides. However, if the diffusive barrier were combined with one or more features that reduced the potential for advection, then transport of radionuclides would be dominated by diffusion and their migration from the EBS would be impeded. Apatite was chosen as the getter material used for this report. Two getter configurations were developed, Case 1 and Case 2. As in the evaluation of the diffusive barrier, the effects of advection, hydrodynamic dispersion, and diffusion on the migration of radionuclides through the getter are evaluated. However, in addition to these mechanisms, the one-dimensional advection/dispersion/diffusion model is modified to include the effect of sorption on radionuclide migration rates through the sorptive medium (getter). As a result of sorption, the longitudinal dispersion coefficient, and the average linear velocity are effectively reduced by the retardation factor. The retardation factor is a function of the getter material's dry bulk density, sorption coefficient and moisture content. The results of the evaluation showed that a significant delay in breakthrough through the getter can be achieved if the thickness of the getter barrier is increased

  1. Development of Draft Regulatory Guide on Accident Analysis for Nuclear Power Plants with New Safety Design Features

    Energy Technology Data Exchange (ETDEWEB)

    Bang, Young Seok; Woo, Sweng Woong; Hwang, Tae Suk [KINS, Daejeon (Korea, Republic of); Sim, Suk K; Hwang, Min Jeong [Environment and Energy Technology, Daejeon (Korea, Republic of)

    2016-05-15

    The present paper discusses the development process of the draft version of regulatory guide (DRG) on accident analysis of the NPP having the NSFD and its result. Based on the consideration on the lesson learned from the previous licensing review, a draft regulatory guide (DRG) on accident analysis for NPP with new safety design features (NSDF) was developed. New safety design features (NSDF) have been introduced to the new constructing nuclear power plants (NPP) since the early 2000 and the issuance of construction permit of SKN Units 3 and 4. Typical examples of the new safety features includes Fluidic Device (FD) within Safety Injection Tanks (SIT), Passive Auxiliary Feedwater System (PAFS), ECCS Core Barrel Duct (ECBD) which were adopted in APR1400 design and/or APR+ design to improve the safety margin of the plants for the postulated accidents of interest. Also several studies of new concept of the safety system such as Hybrid ECCS design have been reported. General and/or specific guideline of accident analysis considering the NSDF has been requested. Realistic evaluation of the impact of NSDF on accident with uncertainty and separated accident analysis accounting the NSDF impact were specified in the DRG. Per the developmental process, identification of key issues, demonstration of the DRG with specific accident with specific NSDF, and improvement of DGR for the key issues and their resolution will be conducted.

  2. Confirming the key role of Ar+ ion bombardment in the growth feature of nanostructured carbon materials by PECVD.

    Science.gov (United States)

    Liu, Yulin; Lin, Jinghuang; Jia, Henan; Chen, Shulin; Qi, Junlei; Qu, Chaoqun; Cao, Jian; Feng, Jicai; Fei, Weidong

    2017-11-24

    In order to confirm the key role of Ar + ion bombardment in the growth feature of nanostructured carbon materials (NCMs), here we report a novel strategy to create different Ar + ion states in situ in plasma enhanced chemical vapor deposition (PECVD) by separating catalyst film from the substrate. Different bombardment environments on either side of the catalyst film were created simultaneously to achieve multi-layered structural NCMs. Results showed that Ar + ion bombardment is crucial and complex for the growth of NCMs. Firstly, Ar + ion bombardment has both positive and negative effects on carbon nanotubes (CNTs). On one hand, Ar + ions can break up the graphic structure of CNTs and suppress thin CNT nucleation and growth. On the other hand, Ar + ion bombardment can remove redundant carbon layers on the surface of large catalyst particles which is essential for thick CNTs. As a result, the diameter of the CNTs depends on the Ar + ion state. As for vertically oriented few-layer graphene (VFG), Ar + ions are essential and can even convert the CNTs into VFG. Therefore, by combining with the catalyst separation method, specific or multi-layered structural NCMs can be obtained by PECVD only by changing the intensity of Ar + ion bombardment, and these special NCMs are promising in many fields.

  3. Confirming the key role of Ar+ ion bombardment in the growth feature of nanostructured carbon materials by PECVD

    Science.gov (United States)

    Liu, Yulin; Lin, Jinghuang; Jia, Henan; Chen, Shulin; Qi, Junlei; Qu, Chaoqun; Cao, Jian; Feng, Jicai; Fei, Weidong

    2017-11-01

    In order to confirm the key role of Ar+ ion bombardment in the growth feature of nanostructured carbon materials (NCMs), here we report a novel strategy to create different Ar+ ion states in situ in plasma enhanced chemical vapor deposition (PECVD) by separating catalyst film from the substrate. Different bombardment environments on either side of the catalyst film were created simultaneously to achieve multi-layered structural NCMs. Results showed that Ar+ ion bombardment is crucial and complex for the growth of NCMs. Firstly, Ar+ ion bombardment has both positive and negative effects on carbon nanotubes (CNTs). On one hand, Ar+ ions can break up the graphic structure of CNTs and suppress thin CNT nucleation and growth. On the other hand, Ar+ ion bombardment can remove redundant carbon layers on the surface of large catalyst particles which is essential for thick CNTs. As a result, the diameter of the CNTs depends on the Ar+ ion state. As for vertically oriented few-layer graphene (VFG), Ar+ ions are essential and can even convert the CNTs into VFG. Therefore, by combining with the catalyst separation method, specific or multi-layered structural NCMs can be obtained by PECVD only by changing the intensity of Ar+ ion bombardment, and these special NCMs are promising in many fields.

  4. ICF reactor economics: identifying the high leverage design features

    International Nuclear Information System (INIS)

    Meier, W.R.; Hogan, W.J.

    1985-01-01

    Parametric studies were carried out for a heavy ion beam (HIB) fusion electric power plant to investigate the effects on the cost of electricity (COE) of variations in several design parameters. In particular, we examined the effects of maximum achievable chamber pulse rate, driver cost, target gain, electric conversion efficiency, and net electric power. We find that with a combination of improvements over our base case, HIB fusion can be economically competitive with other future power sources

  5. The design features of integrated modular water reactor (IMR)

    International Nuclear Information System (INIS)

    Kanagawa, T.; Goto, M.; Usui, S.; Suzuta, T.; Serizawa, A.; Kunugi, T.; Yamauchi, T.; Itoh, G.; Matsumura, T.

    2004-01-01

    Small-to-medium-sized (300-600 MWe) reactors are required for the electric power market in the near future (2010-2030). The main theme in the development of small-to-medium-sized reactor is how to realize competitive cost against other energy sources. As measures to this disadvantage, greatly simplified and small-scale design is needed. From such point of view, Integrated Modular Water Reactor (IMR), whose electric output power is 350 MWe, adopts integrated and high temperature two-phase natural circulation system for the primary system. In this design, main coolant pipes, a pressurizer, and reactor coolant pumps are not needed, and the sizes of the reactor vessel and steam generators are minimized. Additionally, to enhance the economy of the whole plant, fluid systems, and Instrumentation and Control systems of IMR have also been reviewed to make them simplest and smallest taking the advantage of the IMR concept and the state of the art technologies. For example, the integrated primary system and the stand-alone direct heat removal system make the safety system very simple, i.e., no injection, no containment spray, no emergency AC power, etc. The chemical and volume control system is also simplified by eliminating the boron control system and the seal water system of reactor coolant pumps. In this paper, the status of the IMR development and the outline of the IMR design efforts to achieve the simplest and smallest plant are presented. (authors)

  6. Research on Key Technologies of Unit-Based CNC Machine Tool Assembly Design

    OpenAIRE

    Zhongqi Sheng; Lei Zhang; Hualong Xie; Changchun Liu

    2014-01-01

    Assembly is the part that produces the maximum workload and consumed time during product design and manufacturing process. CNC machine tool is the key basic equipment in manufacturing industry and research on assembly design technologies of CNC machine tool has theoretical significance and practical value. This study established a simplified ASRG for CNC machine tool. The connection between parts, semantic information of transmission, and geometric constraint information were quantified to as...

  7. Melding Service Learning and Leadership Skills Development: Keys to Effective Course Design

    Science.gov (United States)

    Lester, Scott W.

    2015-01-01

    The author presents keys to designing a class that successfully melds service learning and student leadership development. These prescriptions are based on the lessons learned over 8 years of teaching a class titled "Community Leadership." This class emphasizes experiential learning and revolves around service learning projects. The…

  8. Fabrication of small mock-ups reflecting the design features of the ITER semi-prototype

    International Nuclear Information System (INIS)

    Jung, Yang-Il; Choi, Byoung-Kwon; Park, Jeong-Yong; Kim, Suk-Kwon; Lee, Dong Won; Kim, Byoung Yoon

    2012-01-01

    The ITER semi-prototype was designed to qualify the manufacturing technology for the ITER blanket first wall. However, its fabrication is expected to face great difficulty due to a design complexity. Even though joining technology for different materials such as beryllium, CuCrZr, and stainless steel (SS) was developed during the first stage of qualification, the joining is still a key issue for the fabrication of the semi-prototype. In this study, small mock-ups (SMU) were fabricated to realize and verify the manufacturing of the semi-prototype reflecting the described design features. The joining of multiple beryllium tiles on the angled CuCrZr surface was confirmed with SMU no. 1. Six beryllium tiles were joined using hot isostatic pressing (HIP), and slitting was then performed to form multiple tiles. In SMU no. 2, HIP was performed two times in order to facilitate the cooling channels at the CuCrZr/SS interface, and to join the beryllium tiles on CuCrZr/SS. The method used to form a pressure boundary for the complex cooling channels was also developed by fabricating the SMU no. 3. The SMUs confirmed the applicability of the HIP for the manufacturing of the semi-prototype.

  9. General features of the neutronics design code EQUICYCLE

    International Nuclear Information System (INIS)

    Jirlow, K.

    1978-10-01

    The neutronics code EQUICYCLE has been developed and improved over a long period of time. It is expecially adapted to survey type design calculations of large fast power reactors with particular emphasis on the nuclear parameters for a realistic equilibrium fuel cycle. Thus the code is used to evaluate the breeding performance, the power distributions and the uranium and plutonium mass balance for realistic refuelling schemes. In addition reactivity coefficients can be calculated and the influence of burnup could be assessed. The code is two-dimensional and treats the reactor core in R-Z geometry. The basic ideas of the calculating scheme are successive iterative improvement of cross-section sets and flux spectra and use of the mid-cycle flux for burning the fuel according to a specified refuelling scheme. Normally given peak burn-ups and maximum power densities are used as boundary conditions. The code is capable of handling the unconventional, so called heterogeneous cores. (author)

  10. Some Key Features and Possible Origin of the Metamorphic Rock-Hosted Gold Mineralization in Buru Island, Indonesia

    Directory of Open Access Journals (Sweden)

    Arifudin Idrus

    2014-07-01

    Full Text Available DOI: 10.17014/ijog.v1i1.172This paper discusses characteristics of some key features of the primary Buru gold deposit as a tool for a better understanding of the deposit genesis. Currently, about 105,000 artisanal and small-scale gold miners (ASGM are operating in two main localities, i.e. Gogorea and Gunung Botak by digging pits/shafts following gold-bearing quartz vein orientation. The gold extraction uses mercury (amalgamation and cyanide processing. The field study identifies two types/generations of quartz veins namely (1 Early quartz veins which are segmented, sigmoidal, dis­continous, and parallel to the foliation of host rock. The quartz vein is lack of sulfides, weak mineralized, crystalline, relatively clear, and maybe poor in gold, and (2 Quartz veins occurred within a ‘mineralized zone’ of about 100 m in width and ~1,000 m in length. The gold mineralization is strongly overprinted by an argillic alteration zone. The mineralization-alteration zone is probably parallel to the mica schist foliation and strongly controlled by N-S or NE-SW-trending structures. The gold-bearing quartz veins are characterized by banded texture particularly colloform following host rock foliation and sulphide banding, brecciated, and rare bladed-like texture. The alteration types consist of propylitic (chlorite, calcite, sericite, argillic, and carbonation represented by graphite banding and carbon flakes. The ore mineralization is characterized by pyrite, native gold, pyrrhotite, and arsenopyrite. Cinnabar, stibnite, chalcopyrite, galena, and sphalerite are rare or maybe absent. In general, sulphide minerals are rare (<3%. Fifteen rock samples were collected in Wamsaid area for geochemical assaying for Au, Ag, As, Sb, Hg, Cu, Pb, and Zn. Eleven of fifteen samples yielded more than 1.00 g/t Au, in which six of them are in excess of 3.00 g/t Au. It can be noted that all high-grade samples are originally or containing limonitic materials, that suggest

  11. Key skills by design: adapting a central Web resource to departmental contexts

    Directory of Open Access Journals (Sweden)

    Claire McAvinia

    2002-12-01

    Full Text Available Web-based delivery of support materials for students has proved to be a popular way of helping small teams to implement key skills policies within universities. The development of 'key' or 'transferable' skills is now encouraged throughout education, but resources (both in terms of staffing and budget tend to be limited. It is difficult for key skills teams to see learners face to face, and not feasible to print or distribute large amounts of paper-based material. Web-based delivery presents a means of overcoming these problems but it can result in generic study skills material simply being published online without due consideration of the needs of different groups of learners within different subject disciplines. Therefore, although a centralized Website for skills provision can overcome logistical problems, it may be perceived as irrelevant or unusable by the student population. This paper presents a model for Web-based delivery of support for key skills which incorporates two separate approaches to the design of these resources. The model was implemented as part of a wider key skills pilot project at University College London, over a period of one year. It includes a 'core' Website, containing information and resources for staff and students. These can also be accessed via customized, departmental key skills homepages. This paper presents the basis for the design choices made in preparing these materials, and the evaluation of some of the pilot departments using them. It then draws some wider conclusions about the effectiveness of this design for supporting skills development.

  12. Academic Primer Series: Five Key Papers about Study Designs in Medical Education.

    Science.gov (United States)

    Gottlieb, Michael; Chan, Teresa M; Fredette, Jenna; Messman, Anne; Robinson, Daniel W; Cooney, Robert; Boysen-Osborn, Megan; Sherbino, Jonathan

    2017-06-01

    A proper understanding of study design is essential to creating successful studies. This is also important when reading or peer reviewing publications. In this article, we aimed to identify and summarize key papers that would be helpful for faculty members interested in learning more about study design in medical education research. The online discussions of the 2016-2017 Academic Life in Emergency Medicine Faculty Incubator program included a robust and vigorous discussion about education study design, which highlighted a number of papers on that topic. We augmented this list of papers with further suggestions by expert mentors. Via this process, we created a list of 29 papers in total on the topic of medical education study design. After gathering these papers, our authorship group engaged in a modified Delphi approach to build consensus on the papers that were most valuable for the understanding of proper study design in medical education. We selected the top five most highly rated papers on the topic domain of study design as determined by our study group. We subsequently summarized these papers with respect to their relevance to junior faculty members and to faculty developers. This article summarizes five key papers addressing study design in medical education with discussions and applications for junior faculty members and faculty developers. These papers provide a basis upon which junior faculty members might build for developing and analyzing studies.

  13. SIMPL Systems, or: Can We Design Cryptographic Hardware without Secret Key Information?

    Science.gov (United States)

    Rührmair, Ulrich

    This paper discusses a new cryptographic primitive termed SIMPL system. Roughly speaking, a SIMPL system is a special type of Physical Unclonable Function (PUF) which possesses a binary description that allows its (slow) public simulation and prediction. Besides this public key like functionality, SIMPL systems have another advantage: No secret information is, or needs to be, contained in SIMPL systems in order to enable cryptographic protocols - neither in the form of a standard binary key, nor as secret information hidden in random, analog features, as it is the case for PUFs. The cryptographic security of SIMPLs instead rests on (i) a physical assumption on their unclonability, and (ii) a computational assumption regarding the complexity of simulating their output. This novel property makes SIMPL systems potentially immune against many known hardware and software attacks, including malware, side channel, invasive, or modeling attacks.

  14. Pill testing or drug checking in Australia: Acceptability of service design features.

    Science.gov (United States)

    Barratt, Monica J; Bruno, Raimondo; Ezard, Nadine; Ritter, Alison

    2018-02-01

    This study aimed to determine design features of a drug-checking service that would be feasible, attractive and likely to be used by Australian festival and nightlife attendees. Web survey of 851 Australians reporting use of psychostimulants and/or hallucinogens and attendance at licensed venues past midnight and/or festivals in the past year (70% male; median age 23 years). A drug-checking service located at festivals or clubs would be used by 94%; a fixed-site service external to such events by 85%. Most (80%) were willing to wait an hour for their result. Almost all (94%) would not use a service if there was a possibility of arrest, and a majority (64%) would not use a service that did not provide individual feedback of results. Drug-checking results were only slightly more attractive if they provided comprehensive quantitative results compared with qualitative results of key ingredients. Most (93%) were willing to pay up to $5, and 68% up to $10, per test. One-third (33%) reported willingness to donate a whole dose for testing: they were more likely to be male, younger, less experienced, use drugs more frequently and attend venues/festivals less frequently. In this sample, festival- or club-based drug-checking services with low wait times and low cost appear broadly attractive under conditions of legal amnesty and individualised feedback. Quantitative analysis of ecstasy pills requiring surrender of a whole pill may appeal to a minority in Australia where pills are more expensive than elsewhere. [Barratt MJ, Bruno R, Ezard N, Ritter A. Pill testing or drug checking in Australia: Acceptability of service design features. Drug Alcohol Rev 2017;00:000-000]. © 2017 Australasian Professional Society on Alcohol and other Drugs.

  15. Comparative effectiveness of instructional design features in simulation-based education: systematic review and meta-analysis.

    Science.gov (United States)

    Cook, David A; Hamstra, Stanley J; Brydges, Ryan; Zendejas, Benjamin; Szostek, Jason H; Wang, Amy T; Erwin, Patricia J; Hatala, Rose

    2013-01-01

    Although technology-enhanced simulation is increasingly used in health professions education, features of effective simulation-based instructional design remain uncertain. Evaluate the effectiveness of instructional design features through a systematic review of studies comparing different simulation-based interventions. We systematically searched MEDLINE, EMBASE, CINAHL, ERIC, PsycINFO, Scopus, key journals, and previous review bibliographies through May 2011. We included original research studies that compared one simulation intervention with another and involved health professions learners. Working in duplicate, we evaluated study quality and abstracted information on learners, outcomes, and instructional design features. We pooled results using random effects meta-analysis. From a pool of 10,903 articles we identified 289 eligible studies enrolling 18,971 trainees, including 208 randomized trials. Inconsistency was usually large (I2 > 50%). For skills outcomes, pooled effect sizes (positive numbers favoring the instructional design feature) were 0.68 for range of difficulty (20 studies; p simulation-based education.

  16. Design features to achieve defence-in-depth in small and medium sized reactors

    International Nuclear Information System (INIS)

    Kuznetsov, Vladimir

    2009-01-01

    Broader incorporation of inherent and passive safety design features has become a 'trademark' of many advanced reactor concepts, including several evolutionary designs and nearly all innovative small and medium sized design concepts. Ensuring adequate defence-in-depth is important for reactors of smaller output because many of them are being designed to allow more proximity to the user, specifically, when non-electrical energy products are targeted. Based on the activities recently performed by the International Atomic Energy Agency, the paper provides a summary description of the design features used to achieve defence in depth in the eleven representative concepts of small and medium sized reactors. (author)

  17. Research on and design of key circuits in RFID tag chip for container management

    Directory of Open Access Journals (Sweden)

    Wang Wenjie

    2016-01-01

    Full Text Available This paper introduces the design of semi-passive RFID tag chip capable of monitoring container safety. A system framework complying with requirements by ISO/IEC 18000-6C is firstly presented, and then differences from the key units of common passive chip, such as switch-state monitoring circuit, power management unit and anti-shake design in baseband processor, are elaborated. The main function of such a chip is to record the container opening frequency during transportation. Finally, the realizations of each unit’s function are simulated.

  18. Research on key technology of planning and design for AC/DC hybrid distribution network

    Science.gov (United States)

    Shen, Yu; Wu, Guilian; Zheng, Huan; Deng, Junpeng; Shi, Pengjia

    2018-04-01

    With the increasing demand of DC generation and DC load, the development of DC technology, AC and DC distribution network integrating will become an important form of future distribution network. In this paper, the key technology of planning and design for AC/DC hybrid distribution network is proposed, including the selection of AC and DC voltage series, the design of typical grid structure and the comprehensive evaluation method of planning scheme. The research results provide some ideas and directions for the future development of AC/DC hybrid distribution network.

  19. [Principles and methodology for ecological rehabilitation and security pattern design in key project construction].

    Science.gov (United States)

    Chen, Li-Ding; Lu, Yi-He; Tian, Hui-Ying; Shi, Qian

    2007-03-01

    Global ecological security becomes increasingly important with the intensive human activities. The function of ecological security is influenced by human activities, and in return, the efficiency of human activities will also be affected by the patterns of regional ecological security. Since the 1990s, China has initiated the construction of key projects "Yangtze Three Gorges Dam", "Qinghai-Tibet Railway", "West-to-East Gas Pipeline", "West-to-East Electricity Transmission" and "South-to-North Water Transfer" , etc. The interaction between these projects and regional ecological security has particularly attracted the attention of Chinese government. It is not only important for the regional environmental protection, but also of significance for the smoothly implementation of various projects aimed to develop an ecological rehabilitation system and to design a regional ecological security pattern. This paper made a systematic analysis on the types and characteristics of key project construction and their effects on the environment, and on the basis of this, brought forward the basic principles and methodology for ecological rehabilitation and security pattern design in this construction. It was considered that the following issues should be addressed in the implementation of a key project: 1) analysis and evaluation of current regional ecological environment, 2) evaluation of anthropogenic disturbances and their ecological risk, 3) regional ecological rehabilitation and security pattern design, 4) scenario analysis of environmental benefits of regional ecological security pattern, 5) re-optimization of regional ecological system framework, and 6) establishment of regional ecosystem management plan.

  20. Key technological issues in LMFBR high-temperature structural design - the US perspective

    International Nuclear Information System (INIS)

    Corum, J.M.

    1984-01-01

    The purpose of this paper is: (1) to review the key technological issues in LMFBR high-temperature structural design, particularly as they relate to cost reduction; and (2) to provide an overview of activities sponsored by the US Department of Energy to resolve the issues and to establish stable, standardized, and defensible structural design methods and criteria. Specific areas of discussion include: weldments, structural validation tests, simplified design analysis procedures, design procedures for piping, validation of the methodology for notch-like geometries, improved life assessment procedures, thermal striping, extension of the methodology to new materials, and ASME high-temperature Code reform needs. The perceived problems and needs in each area are discussed, and the current status of related US activities is given

  1. A Web-Based Data Collection Platform for Multisite Randomized Behavioral Intervention Trials: Development, Key Software Features, and Results of a User Survey.

    Science.gov (United States)

    Modi, Riddhi A; Mugavero, Michael J; Amico, Rivet K; Keruly, Jeanne; Quinlivan, Evelyn Byrd; Crane, Heidi M; Guzman, Alfredo; Zinski, Anne; Montue, Solange; Roytburd, Katya; Church, Anna; Willig, James H

    2017-06-16

    Meticulous tracking of study data must begin early in the study recruitment phase and must account for regulatory compliance, minimize missing data, and provide high information integrity and/or reduction of errors. In behavioral intervention trials, participants typically complete several study procedures at different time points. Among HIV-infected patients, behavioral interventions can favorably affect health outcomes. In order to empower newly diagnosed HIV positive individuals to learn skills to enhance retention in HIV care, we developed the behavioral health intervention Integrating ENGagement and Adherence Goals upon Entry (iENGAGE) funded by the National Institute of Allergy and Infectious Diseases (NIAID), where we deployed an in-clinic behavioral health intervention in 4 urban HIV outpatient clinics in the United States. To scale our intervention strategy homogenously across sites, we developed software that would function as a behavioral sciences research platform. This manuscript aimed to: (1) describe the design and implementation of a Web-based software application to facilitate deployment of a multisite behavioral science intervention; and (2) report on results of a survey to capture end-user perspectives of the impact of this platform on the conduct of a behavioral intervention trial. In order to support the implementation of the NIAID-funded trial iENGAGE, we developed software to deploy a 4-site behavioral intervention for new clinic patients with HIV/AIDS. We integrated the study coordinator into the informatics team to participate in the software development process. Here, we report the key software features and the results of the 25-item survey to evaluate user perspectives on research and intervention activities specific to the iENGAGE trial (N=13). The key features addressed are study enrollment, participant randomization, real-time data collection, facilitation of longitudinal workflow, reporting, and reusability. We found 100% user

  2. Cigarette Design Features: Effects on Emission Levels, User Perception, and Behavior.

    NARCIS (Netherlands)

    Talhout, Reinskje; Richter, Patricia A; Stepanov, Irina; Watson, Christina V; Watson, Clifford H

    This paper describes the effects of non-tobacco, physical cigarette design features on smoke emissions, product appeal, and smoking behaviors - 3 factors that determine smoker's exposure and related health risks.

  3. Comparing infants' use of featural and spatiotemporal information when individuating objects in an event monitoring design

    DEFF Research Database (Denmark)

    Krøjgaard, Peter

    . The results obtained using this design reveal that infants are more successful using spatiotemporal object information than when using featural information. However, recent studies using the less cognitively demanding event monitoring design have revealed that even younger infants are capable of object...... in the present series of experiments in which infants' use of spatiotemporal and featural information is compared directly using the less demanding event monitoring design. The results are discussed in relation to existing empirical evidence......., to what extent infants rely on spatiotemporal or featural object information when individuating objects is currently under debate. Hitherto, infants' use of spatiotemporal and featural object information has only been compared directly using the rather cognitively demanding event mapping design...

  4. Nutrition warnings as front-of-pack labels: influence of design features on healthfulness perception and attentional capture.

    Science.gov (United States)

    Cabrera, Manuel; Machín, Leandro; Arrúa, Alejandra; Antúnez, Lucía; Curutchet, María Rosa; Giménez, Ana; Ares, Gastón

    2017-12-01

    Warnings are a new directive front-of-pack (FOP) nutrition labelling scheme that highlights products with high content of key nutrients. The design of warnings influences their ability to catch consumers' attention and to clearly communicate their intended meaning, which are key determinants of their effectiveness. The aim of the present work was to evaluate the influence of design features of warnings as a FOP nutrition labelling scheme on perceived healthfulness and attentional capture. Five studies with a total of 496 people were carried out. In the first study, the association of colour and perceived healthfulness was evaluated in an online survey in which participants had to rate their perceived healthfulness of eight colours. In the second study, the influence of colour, shape and textual information on perceived healthfulness was evaluated using choice-conjoint analysis. The third study focused on implicit associations between two design features (shape and colour) on perceived healthfulness. The fourth and fifth studies used visual search to evaluate the influence of colour, size and position of the warnings on attentional capture. Perceived healthfulness was significantly influenced by shape, colour and textual information. Colour was the variable with the largest contribution to perceived healthfulness. Colour, size and position of the warnings on the labels affected attentional capture. Results from the experiments provide recommendations for the design of warnings to identify products with unfavourable nutrient profile.

  5. Design features for enhancing international safeguards of AFR dry storage for spent LWR fuel

    International Nuclear Information System (INIS)

    Roberts, F.P.; Harms, N.L.

    1985-05-01

    The Pacific Northwest Laboratory has performed a study for the Nuclear Regulatory Commission to identify and analyze design features that can facilitate the implementation of IAEA safeguards at facilities for dry storage of light water reactor spent fuels. Specific design features are identified that can enhance nuclear material flow and inventory verification. These are assessed from the viewpoint of safeguards effectiveness and possible impacts on the IAEA and the operator of the AFR facility. 11 refs., 3 figs., 2 tabs

  6. Key Aspects of Nucleic Acid Library Design for in Vitro Selection

    Science.gov (United States)

    Vorobyeva, Maria A.; Davydova, Anna S.; Vorobjev, Pavel E.; Pyshnyi, Dmitrii V.; Venyaminova, Alya G.

    2018-01-01

    Nucleic acid aptamers capable of selectively recognizing their target molecules have nowadays been established as powerful and tunable tools for biospecific applications, be it therapeutics, drug delivery systems or biosensors. It is now generally acknowledged that in vitro selection enables one to generate aptamers to almost any target of interest. However, the success of selection and the affinity of the resulting aptamers depend to a large extent on the nature and design of an initial random nucleic acid library. In this review, we summarize and discuss the most important features of the design of nucleic acid libraries for in vitro selection such as the nature of the library (DNA, RNA or modified nucleotides), the length of a randomized region and the presence of fixed sequences. We also compare and contrast different randomization strategies and consider computer methods of library design and some other aspects. PMID:29401748

  7. Housing Stakeholder Preferences for the “Soft” Features of Sustainable and Healthy Housing Design in the UK

    Science.gov (United States)

    Prochorskaite, Agne; Couch, Chris; Malys, Naglis; Maliene, Vida

    2016-01-01

    It is widely recognised that the quantity and sustainability of new homes in the UK need to increase. However, it is important that sustainable housing is regarded holistically, and not merely in environmental terms, and incorporates elements that enhance the quality of life, health and well-being of its users. This paper focuses on the “soft” features of sustainable housing, that is, the non-technological components of sustainable housing and neighbourhood design that can impact occupants’ health and well-being. Aims of the study are to ascertain the relative level of importance that key housing stakeholders attach to these features and to investigate whether the opinions of housing users and housing providers are aligned with regards to their importance. An online survey was carried out to gauge the level of importance that the key stakeholders, such as housing users, local authorities, housing associations, and developers (n = 235), attach to these features. Results revealed that while suitable indoor space was the feature regarded as most important by all stakeholders, there were also a number of disparities in opinion between housing users and housing providers (and among the different types of providers). This implies a scope for initiatives to achieve a better alignment between housing users and providers. PMID:26751465

  8. Electronic assessment of clinical reasoning in clerkships: A mixed-methods comparison of long-menu key-feature problems with context-rich single best answer questions

    NARCIS (Netherlands)

    Huwendiek, S.; Reichert, F.; Duncker, C.; Leng, B.A. De; Vleuten, C.P.M. van der; Muijtjens, A.M.; Bosse, H.M.; Haag, M.; Hoffmann, G.F.; Tonshoff, B.; Dolmans, D.

    2017-01-01

    BACKGROUND: It remains unclear which item format would best suit the assessment of clinical reasoning: context-rich single best answer questions (crSBAs) or key-feature problems (KFPs). This study compared KFPs and crSBAs with respect to students' acceptance, their educational impact, and

  9. Design for manufacturing and assembly key performance indicators to support high-speed product development

    DEFF Research Database (Denmark)

    Thompson, Mary Kathryn; Juel Jespersen, Ida Kirstine; Kjærgaard, Thomas

    2018-01-01

    Design for Manufacturing and Assembly (DfMA) has great potential for minimizing late engineering changes (ECs) that impede high-speed product development and delay time-to-profit. However, our understanding of DfMA and its implementation in industry is still incomplete. This paper presents...... an industrial case study on late ECs in high-speed product development and compares the results to other examples from the literature. It then proposes a framework with sets of key performance indicators (KPIs) to measure and improve producability and product quality throughout the product development process....

  10. Design features of Beijing Shijingshan 3 x 200 MW cogeneration plant

    International Nuclear Information System (INIS)

    Li, T.X.; Ou, Y.Z.

    1991-01-01

    This paper describes the design feature of Beijing Shijingshan 3 x 200 MW Cogeneration Plant. The design optimized the scheme and system of 200 MW units for heating. The cogeneration plant has achieved comprehensive economic benefit in energy saving and environmental pollution reduction

  11. Accommodation of unprotected accidents by inherent safety design features in metallic and oxide-fueled LMFBRs

    International Nuclear Information System (INIS)

    Cahalan, J.E.; Sevy, R.H.; Su, S.F.

    1985-01-01

    This paper presents the results of a study of the effectivness of intrinsic design features to mitigate the consequences of unprotected accidents in metallic and oxide-fueled LMFBRs. The accidents analyzed belong to the class generally considered to lead to core disruption; unprotected loss-of-flow (LOF) and transient over-power (TOP). Results of the study demonstrate the potential for design features to meliorate accident consequences, and in some cases to render them benign. Emphasis is placed on the relative performance of metallic and oxide-fueled core designs

  12. A new design of pulsed laser diode driver system for multistate quantum key distribution

    Science.gov (United States)

    Abdullah, M. S.; Jamaludin, M. Z.; Witjaksono, G.; Mokhtar, M. H. H.

    2011-07-01

    In this paper, we describe a new design of laser diode driver system based on MOSFET current mirror and digital signal controller (DSC). The system is designed to emit stream pairs of photons from three semiconductor laser diodes. The DSC is able to switch between the three laser diodes at constant rate. The duty cycle is maintained at 1% in order to reduce its thermal effect and thus prolong the laser diodes' life cycles. The MOSFET current mirror circuits are capable of delivering constant modulation current with peak current up to 58 mA to each laser diode. This laser driver system will allow the generating biphotons automatically with qubit rate around 8-13% for μ less than or equal to 1, thus making it practical for six-states quantum key distribution implementation.

  13. A regression-based Kansei engineering system based on form feature lines for product form design

    Directory of Open Access Journals (Sweden)

    Yan Xiong

    2016-06-01

    Full Text Available When developing new products, it is important for a designer to understand users’ perceptions and develop product form with the corresponding perceptions. In order to establish the mapping between users’ perceptions and product design features effectively, in this study, we presented a regression-based Kansei engineering system based on form feature lines for product form design. First according to the characteristics of design concept representation, product form features–product form feature lines were defined. Second, Kansei words were chosen to describe image perceptions toward product samples. Then, multiple linear regression and support vector regression were used to construct the models, respectively, that predicted users’ image perceptions. Using mobile phones as experimental samples, Kansei prediction models were established based on the front view form feature lines of the samples. From the experimental results, these two predict models were of good adaptability. But in contrast to multiple linear regression, the predict performance of support vector regression model was better, and support vector regression is more suitable for form regression prediction. The results of the case showed that the proposed method provided an effective means for designers to manipulate product features as a whole, and it can optimize Kansei model and improve practical values.

  14. Examining the design features of a communication-rich, problem-centred mathematics professional development

    Science.gov (United States)

    de Araujo, Zandra; Orrill, Chandra Hawley; Jacobson, Erik

    2018-04-01

    While there is considerable scholarship describing principles for effective professional development, there have been few attempts to examine these principles in practice. In this paper, we identify and examine the particular design features of a mathematics professional development experience provided for middle grades teachers over 14 weeks. The professional development was grounded in a set of mathematical tasks that each had one right answer, but multiple solution paths. The facilitator engaged participants in problem solving and encouraged participants to work collaboratively to explore different solution paths. Through analysis of this collaborative learning environment, we identified five design features for supporting teacher learning of important mathematics and pedagogy in a problem-solving setting. We discuss these design features in depth and illustrate them by presenting an elaborated example from the professional development. This study extends the existing guidance for the design of professional development by examining and operationalizing the relationships among research-based features of effective professional development and the enacted features of a particular design.

  15. Sensitivity of Key Parameters in Aerodynamic Wind Turbine Rotor Design on Power and Energy Performance

    International Nuclear Information System (INIS)

    Bak, Christian

    2007-01-01

    In this paper the influence of different key parameters in aerodynamic wind turbine rotor design on the power efficiency, C p , and energy production has been investigated. The work was divided into an analysis of 2D airfoils/blade sections and of entire rotors. In the analysis of the 2D airfoils it was seen that there was a maximum of the local C p for airfoils with finite maximum C l /C d values. The local speed ratio should be between 2.4 and 3.8 for airfoils with maximum c l /c d between 50 and 200, respectively, to obtain maximum local C p . Also, the investigation showed that Re had a significant impact on CP and especially for Re p for rotors was made with three blades and showed that with the assumption of constant maximum c l /c d along the entire blade, the design tip speed ratio changed from X=6 to X=12 for c l /cd=50 and c l /c d =200, respectively, with corresponding values of maximum c p of 0.46 and 0.525. An analysis of existing rotors re-designed with new airfoils but maintaining the absolute thickness distribution to maintain the stiffness showed that big rotors are more aerodynamic efficient than small rotors caused by higher Re. It also showed that the design tip speed ratio was very dependent on the rotor size and on the assumptions of the airfoil flow being fully turbulent (contaminated airfoil) or free transitional (clean airfoil). The investigations showed that rotors with diameter D=1.75m, should be designed for X around 5.5, whereas rotors with diameter D=126m, should be designed for Xbetween 6.5 and 8.5, depending on the airfoil performance

  16. Phase information of time-frequency transforms as a key feature for classification of atrial fibrillation episodes

    International Nuclear Information System (INIS)

    Ortigosa, Nuria; Fernández, Carmen; Galbis, Antonio; Cano, Óscar

    2015-01-01

    Patients suffering from atrial fibrillation can be classified into different subtypes, according to the temporal pattern of the arrhythmia and its recurrence. Nowadays, clinicians cannot differentiate a priori between the different subtypes, and patient classification is done afterwards, when its clinical course is available. In this paper we present a comparison of classification performances when differentiating paroxysmal and persistent atrial fibrillation episodes by means of support vector machines. We analyze short surface electrocardiogram recordings by extracting modulus and phase features from several time-frequency transforms: short-time Fourier transform, Wigner–Ville, Choi–Williams, Stockwell transform, and general Fourier-family transform. Overall, accuracy higher than 81% is obtained when classifying phase information features of real test ECGs from a heterogeneous cohort of patients (in terms of progression of the arrhythmia and antiarrhythmic treatment) recorded in a tertiary center. Therefore, phase features can facilitate the clinicians’ choice of the most appropriate treatment for each patient by means of a non-invasive technique (the surface ECG). (paper)

  17. The design features and safety concepts of the nuclear heating reactor developed in China

    International Nuclear Information System (INIS)

    Zheng Wenxiang; Wang Dazhong

    1995-01-01

    Based on the specific conditions of the nuclear heat applications and the development objectives of the advanced reactors, the nuclear heating reactor (NHR) exploited in China has adhered to the new safety concepts and been designed with a number of advanced features, including the integrated arrangement, full power natural circulation capacity, self-pressurized performance, dynamically-hydraulic control rod drive and passive safety systems, so that higher standard of safety as well as simplification in the plant systems and improvement in economic viability has been achieved. This paper describes the special consideration in the design as well as the main design features and safety concepts of the NHR. Some experimental and analytical results are also presented to demonstrate the NHR safety features

  18. Plant modeling as a key tool for nuclear I and C design and V and V

    International Nuclear Information System (INIS)

    Krasnov, V.; Sokolov, O.; Symkin, B.

    2006-01-01

    This paper summarizes an intensive experience of LvivORGRES in the design and implementation of the digital control systems at VVER-1000 and VVER-440 nuclear power plants in Ukraine and Bulgaria. This experience is applicable to the digital I and C upgrade projects for other types of reactor equipment as well as to the design and testing of new I and C systems for new constructions. LvivORGRES was recently involved in several modernization projects as a functional designer and, also, provided technical support and supervision during the factory and site acceptance testing. It is widely accepted and proved by the industry's practice that a level and quality of system validation at all design and implementation phases are key to the successful future operation of I and C systems. The plant control systems have some additional validation requirements in comparing with the information and monitoring systems. According to the Ukrainian nuclear regulation standards, the scope of the control system projects should include the close loop stability analysis at all unit modes of operation. Besides the control system algorithms verification and validation, it was necessary to determine the tuning parameters for the system and use them initially during the system commissioning. LvivORGRES has developed the Adaptive Plant Modeling process that was used as a key tool in all design stages of control system upgrade projects: Software engineering tests, Integrated system validation tests, Factory acceptance tests. The Plant Model was developed on a modular basis which allowed the testing of all primary and secondary side regulators for all unit modes of operation including transients and unit start-up and shutdown. The Plant Model has been adapted to each project's requirements. The use of the plant simulation provided technical bases for important project decisions and documents including among others: system test strategy, initial tuning parameters, training plan, etc. The Plant

  19. Key Design Considerations When Calculating Cost Savings for Population Health Management Programs in an Observational Setting.

    Science.gov (United States)

    Murphy, Shannon M E; Hough, Douglas E; Sylvia, Martha L; Dunbar, Linda J; Frick, Kevin D

    2018-02-08

    To illustrate the impact of key quasi-experimental design elements on cost savings measurement for population health management (PHM) programs. Population health management program records and Medicaid claims and enrollment data from December 2011 through March 2016. The study uses a difference-in-difference design to compare changes in cost and utilization outcomes between program participants and propensity score-matched nonparticipants. Comparisons of measured savings are made based on (1) stable versus dynamic population enrollment and (2) all eligible versus enrolled-only participant definitions. Options for the operationalization of time are also discussed. Individual-level Medicaid administrative and claims data and PHM program records are used to match study groups on baseline risk factors and assess changes in costs and utilization. Savings estimates are statistically similar but smaller in magnitude when eliminating variability based on duration of population enrollment and when evaluating program impact on the entire target population. Measurement in calendar time, when possible, simplifies interpretability. Program evaluation design elements, including population stability and participant definitions, can influence the estimated magnitude of program savings for the payer and should be considered carefully. Time specifications can also affect interpretability and usefulness. © Health Research and Educational Trust.

  20. Design and test performance of the ATLAS Feature Extractor trigger boards for the Phase-1 Upgrade

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00222228; The ATLAS collaboration

    2017-01-01

    In Run 3, the ATLAS Level-1 Calorimeter Trigger will be augmented by an Electron Feature Extractor (eFEX), to identify isolated e/g and particles, and a Jet Feature Extractor (jFEX), to identify energetic jets and calculate various local energy sums. Each module accommodates more than 450 differential signals that can operate at up to 12.8 Gb/s, some of which are routed over 30 cm between FPGAs. Presented here are the module designs, the processes that have been adopted to meet the challenges associated with multi-Gb/s PCB design, and the results of tests that characterize the performance of these modules.

  1. Content and Design Features of Academic Health Sciences Libraries' Home Pages.

    Science.gov (United States)

    McConnaughy, Rozalynd P; Wilson, Steven P

    2018-01-01

    The goal of this content analysis was to identify commonly used content and design features of academic health sciences library home pages. After developing a checklist, data were collected from 135 academic health sciences library home pages. The core components of these library home pages included a contact phone number, a contact email address, an Ask-a-Librarian feature, the physical address listed, a feedback/suggestions link, subject guides, a discovery tool or database-specific search box, multimedia, social media, a site search option, a responsive web design, and a copyright year or update date.

  2. Defining key features of the broad autism phenotype: a comparison across parents of multiple- and single-incidence autism families.

    Science.gov (United States)

    Losh, Molly; Childress, Debra; Lam, Kristen; Piven, Joseph

    2008-06-05

    This study examined the frequency of personality, language, and social-behavioral characteristics believed to comprise the broad autism phenotype (BAP), across families differing in genetic liability to autism. We hypothesized that within this unique sample comprised of multiple-incidence autism families (MIAF), single-incidence autism families (SIAF), and control Down syndrome families (DWNS), a graded expression would be observed for the principal characteristics conferring genetic susceptibility to autism, in which such features would express most profoundly among parents from MIAFs, less strongly among SIAFs, and least of all among comparison parents from DWNS families, who should display population base rates. Analyses detected linear expression of traits in line with hypotheses, and further suggested differential intrafamilial expression across family types. In the vast majority of MIAFs both parents displayed BAP characteristics, whereas within SIAFs, it was equally likely that one, both, or neither parent show BAP features. The significance of these findings is discussed in relation to etiologic mechanisms in autism and relevance to molecular genetic studies. (c) 2007 Wiley-Liss, Inc.

  3. A study on HCI design strategy using emergent features and response time

    International Nuclear Information System (INIS)

    Lee, Sung Jin; Chang, Soon Heung; Park, Jin Gyun

    2001-01-01

    Existing design process of user interface has some weak point that there is no feedback information and no quantitative information between each sub process. If they're such information in design process, the design time cycle will be decreased and the contentment of HCI in the aspect of user will be more easily archived. In this study, new design process with feedback information and quantitative information was proposed using emergent features and user response time. The proposed methodology was put together with three main parts. First part is to calculate distinctiveness of a user interface or expanded user interface with consideration of emergent features. Second part is to expand a prototype user interface with design option for purpose of design requirement using directed structure graph (or nodal graph) theory. Last part is to convert non-realized value, distinctiveness, into realized value, response time, by response time database or response time correlation in the form of Hick-Hyman law equation. From the present validations, the usefulness of the proposed methodology was obtained by simple validation testing. It was found that emergent features should be improved for high reflection of real user interface. For the reliability of response time database, lots of end-user experiment is necessary. Expansion algorithm and representation technique of qualitative information should be somewhat improved for more efficient design process

  4. Features of CRISPR-Cas Regulation Key to Highly Efficient and Temporally-Specific crRNA Production

    Directory of Open Access Journals (Sweden)

    Andjela Rodic

    2017-11-01

    Full Text Available Bacterial immune systems, such as CRISPR-Cas or restriction-modification (R-M systems, affect bacterial pathogenicity and antibiotic resistance by modulating horizontal gene flow. A model system for CRISPR-Cas regulation, the Type I-E system from Escherichia coli, is silent under standard laboratory conditions and experimentally observing the dynamics of CRISPR-Cas activation is challenging. Two characteristic features of CRISPR-Cas regulation in E. coli are cooperative transcription repression of cas gene and CRISPR array promoters, and fast non-specific degradation of full length CRISPR transcripts (pre-crRNA. In this work, we use computational modeling to understand how these features affect the system expression dynamics. Signaling which leads to CRISPR-Cas activation is currently unknown, so to bypass this step, we here propose a conceptual setup for cas expression activation, where cas genes are put under transcription control typical for a restriction-modification (R-M system and then introduced into a cell. Known transcription regulation of an R-M system is used as a proxy for currently unknown CRISPR-Cas transcription control, as both systems are characterized by high cooperativity, which is likely related to similar dynamical constraints of their function. We find that the two characteristic CRISPR-Cas control features are responsible for its temporally-specific dynamical response, so that the system makes a steep (switch-like transition from OFF to ON state with a time-delay controlled by pre-crRNA degradation rate. We furthermore find that cooperative transcription regulation qualitatively leads to a cross-over to a regime where, at higher pre-crRNA processing rates, crRNA generation approaches the limit of an infinitely abrupt system induction. We propose that these dynamical properties are associated with rapid expression of CRISPR-Cas components and efficient protection of bacterial cells against foreign DNA. In terms of synthetic

  5. Multi-objective optimization of generalized reliability design problems using feature models-A concept for early design stages

    International Nuclear Information System (INIS)

    Limbourg, Philipp; Kochs, Hans-Dieter

    2008-01-01

    Reliability optimization problems such as the redundancy allocation problem (RAP) have been of considerable interest in the past. However, due to the restrictions of the design space formulation, they may not be applicable in all practical design problems. A method with high modelling freedom for rapid design screening is desirable, especially in early design stages. This work presents a novel approach to reliability optimization. Feature modelling, a specification method originating from software engineering, is applied for the fast specification and enumeration of complex design spaces. It is shown how feature models can not only describe arbitrary RAPs but also much more complex design problems. The design screening is accomplished by a multi-objective evolutionary algorithm for probabilistic objectives. Comparing averages or medians may hide the true characteristics of this distributions. Therefore the algorithm uses solely the probability of a system dominating another to achieve the Pareto optimal set. We illustrate the approach by specifying a RAP and a more complex design space and screening them with the evolutionary algorithm

  6. Assessing Key Epistemic Features of Didactic-Mathematical Knowledge of Prospective Teachers: The Case of The Derivative

    Science.gov (United States)

    Pino-Fan, Luis R.; Godino, Juan D.; Font, Vicenç

    2018-01-01

    In recent years, there has been a growing interest in studying the knowledge that mathematics teachers require in order for their teaching to be effective. However, only a few studies have focused on the design and application of instruments that are capable of exploring different aspects of teachers' didactic-mathematical knowledge about specific…

  7. Joint Feature Extraction and Classifier Design for ECG-Based Biometric Recognition.

    Science.gov (United States)

    Gutta, Sandeep; Cheng, Qi

    2016-03-01

    Traditional biometric recognition systems often utilize physiological traits such as fingerprint, face, iris, etc. Recent years have seen a growing interest in electrocardiogram (ECG)-based biometric recognition techniques, especially in the field of clinical medicine. In existing ECG-based biometric recognition methods, feature extraction and classifier design are usually performed separately. In this paper, a multitask learning approach is proposed, in which feature extraction and classifier design are carried out simultaneously. Weights are assigned to the features within the kernel of each task. We decompose the matrix consisting of all the feature weights into sparse and low-rank components. The sparse component determines the features that are relevant to identify each individual, and the low-rank component determines the common feature subspace that is relevant to identify all the subjects. A fast optimization algorithm is developed, which requires only the first-order information. The performance of the proposed approach is demonstrated through experiments using the MIT-BIH Normal Sinus Rhythm database.

  8. Design and safety features of commercial nuclear power plants in Japan, 1976 edition

    International Nuclear Information System (INIS)

    Izumi, Fumio; Harayama, Yasuo

    1976-10-01

    The December 1975 edition (JAERI-M 5959) contained design particulars and safety features of 20 commercial nuclear power plants in Japan as of December 1974. Subsequently new plants have been put into operation and some plants under construction have undergone design modifications. The present edition presents similar data of the commercial nuclear power plants in Japan up to June 1976, compiled by computer processing. (auth.)

  9. Structural and compositional features of high-rise buildings: experimental design in Yekaterinburg

    Science.gov (United States)

    Yankovskaya, Yulia; Lobanov, Yuriy; Temnov, Vladimir

    2018-03-01

    The study looks at the specifics of high-rise development in Yekaterinburg. High-rise buildings are considered in the context of their historical development, structural features, compositional and imaginative design techniques. Experience of Yekaterinburg architects in experimental design is considered and analyzed. Main issues and prospects of high-rise development within the Yekaterinburg structure are studied. The most interesting and significant conceptual approaches to the structural and compositional arrangement of high-rise buildings are discussed.

  10. Research on Key Technologies of Unit-Based CNC Machine Tool Assembly Design

    Directory of Open Access Journals (Sweden)

    Zhongqi Sheng

    2014-01-01

    Full Text Available Assembly is the part that produces the maximum workload and consumed time during product design and manufacturing process. CNC machine tool is the key basic equipment in manufacturing industry and research on assembly design technologies of CNC machine tool has theoretical significance and practical value. This study established a simplified ASRG for CNC machine tool. The connection between parts, semantic information of transmission, and geometric constraint information were quantified to assembly connection strength to depict the assembling difficulty level. The transmissibility based on trust relationship was applied on the assembly connection strength. Assembly unit partition based on assembly connection strength was conducted, and interferential assembly units were identified and revised. The assembly sequence planning and optimization of parts in each assembly unit and between assembly units was conducted using genetic algorithm. With certain type of high speed CNC turning center, as an example, this paper explored into the assembly modeling, assembly unit partition, and assembly sequence planning and optimization and realized the optimized assembly sequence of headstock of CNC machine tool.

  11. Comparability and Usability: Key issues in the design of internet forms for New Zealand’s 2006 Census of Populations and Dwellings

    Directory of Open Access Journals (Sweden)

    Lyn Potaka

    2008-03-01

    Full Text Available Designing internet questionnaires to collect data that will ultimately be comparable with the data collected from paper questionnaires can present a number of challenges for developers. This paper discusses the design and development of internet forms for use in a mixed-mode Census in New Zealand in 2006. Using experiences from the design and testing of prototype forms, it describes design features intended to take full advantage of the capabilities of the internet mode, while preserving the qualities of paper based responding to help prevent mode effects. The discussion also highlights the role of usability testing as a key tool in evaluating the success of those design strategies and ensuring that the forms would be simple and easy to use.

  12. Design Features and Technology Uncertainties for the Next Generation Nuclear Plant

    Energy Technology Data Exchange (ETDEWEB)

    John M. Ryskamp; Phil Hildebrandt; Osamu Baba; Ron Ballinger; Robert Brodsky; Hans-Wolfgang Chi; Dennis Crutchfield; Herb Estrada; Jeane-Claude Garnier; Gerald Gordon; Richard Hobbins; Dan Keuter; Marilyn Kray; Philippe Martin; Steve Melancon; Christian Simon; Henry Stone; Robert Varrin; Werner von Lensa

    2004-06-01

    This report presents the conclusions, observations, and recommendations of the Independent Technology Review Group (ITRG) regarding design features and important technology uncertainties associated with very-high-temperature nuclear system concepts for the Next Generation Nuclear Plant (NGNP). The ITRG performed its reviews during the period November 2003 through April 2004.

  13. The pit ventilation features and the design principle of ventilation system in trackless mining uranium mine

    International Nuclear Information System (INIS)

    Deng Wenhui; Zhou Xinghuo; Li Xianjie

    2001-01-01

    According to the pit arrangement features of trackless mining uranium mine, based on the fundamental of radon permeation and control, and analysis of radon pollution characteristics and radon education, the design principle of ventilation system in trackless mining uranium mine has been raised

  14. Gender Differences in Figural Matrices: The Moderating Role of Item Design Features

    Science.gov (United States)

    Arendasy, Martin E.; Sommer, Markus

    2012-01-01

    There is a heated debate on whether observed gender differences in some figural matrices in adults can be attributed to gender differences in inductive reasoning/G[subscript f] or differential item functioning and/or test bias. Based on previous studies we hypothesized that three specific item design features moderate the effect size of the gender…

  15. Examining the Design Features of a Communication-Rich, Problem-Centred Mathematics Professional Development

    Science.gov (United States)

    de Araujo, Zandra; Orrill, Chandra Hawley; Jacobson, Erik

    2018-01-01

    While there is considerable scholarship describing principles for effective professional development, there have been few attempts to examine these principles in practice. In this paper, we identify and examine the particular design features of a mathematics professional development experience provided for middle grades teachers over 14 weeks. The…

  16. Low cost, small form factor, and integration as the key features for the optical component industry takeoff

    Science.gov (United States)

    Schiattone, Francesco; Bonino, Stefano; Gobbi, Luigi; Groppi, Angelamaria; Marazzi, Marco; Musio, Maurizio

    2003-04-01

    In the past the optical component market has been mainly driven by performances. Today, as the number of competitors has drastically increased, the system integrators have a wide range of possible suppliers and solutions giving them the possibility to be more focused on cost and also on footprint reduction. So, if performances are still essential, low cost and Small Form Factor issues are becoming more and more crucial in selecting components. Another evolution in the market is the current request of the optical system companies to simplify the supply chain in order to reduce the assembling and testing steps at system level. This corresponds to a growing demand in providing subassemblies, modules or hybrid integrated components: that means also Integration will be an issue in which all the optical component companies will compete to gain market shares. As we can see looking several examples offered by electronic market, to combine low cost and SFF is a very challenging task but Integration can help in achieving both features. In this work we present how these issues could be approached giving examples of some advanced solutions applied to LiNbO3 modulators. In particular we describe the progress made on automation, new materials and low cost fabrication methods for the parts. We also introduce an approach in integrating optical and electrical functionality on LiNbO3 modulators including RF driver, bias control loop, attenuator and photodiode integrated in a single device.

  17. A review of the surface features and properties, surfactant adsorption and floatability of four key minerals of diasporic bauxite resources.

    Science.gov (United States)

    Zhang, Ningning; Nguyen, Anh V; Zhou, Changchun

    2018-04-01

    Diasporic bauxite represents one of the major aluminum resources. Its upgrading for further processing involves a separation of diaspore (the valuable mineral) from aluminosilicates (the gangue minerals) such as kaolinite, illite, and pyrophyllite. Flotation is one of the most effective ways to realize the upgrading. Since flotation is a physicochemical process based on the difference in the surface hydrophobicity of different components, determining the adsorption characteristics of various flotation surfactants on the mineral surfaces is critical. The surfactant adsorption properties of the minerals, in turn, are controlled by the surface chemistry of the minerals, while the latter is related to the mineral crystal structures. In this paper, we first discuss the crystal structures of the four key minerals of diaspore, kaolinite, illite, and pyrophyllite as well as the broken bonds on their exposed surfaces after grinding. Next, we summarize the surface chemistry properties such as surface wettability and surface electrical properties of the four minerals, and the differences in these properties are explained from the perspective of mineral crystal structures. Then we review the adsorption mechanism and adsorption characteristics of surfactants such as collectors (cationic, anionic, and mixed surfactants), depressants (inorganic and organic), dispersants, and flocculants on these mineral surfaces. The separation of diaspore and aluminosilicates by direct flotation and reverse flotation are reviewed, and the collecting properties of different types of collectors are compared. Furthermore, the abnormal behavior of the cationic flotation of kaolinite is also explained in this section. This review provides a strong theoretical support for the optimization of the upgrading of diaspore bauxite ore by flotation and the early industrialization of the reverse flotation process. Copyright © 2018 Elsevier B.V. All rights reserved.

  18. Where's the Noise? Key Features of Spontaneous Activity and Neural Variability Arise through Learning in a Deterministic Network.

    Directory of Open Access Journals (Sweden)

    Christoph Hartmann

    2015-12-01

    Full Text Available Even in the absence of sensory stimulation the brain is spontaneously active. This background "noise" seems to be the dominant cause of the notoriously high trial-to-trial variability of neural recordings. Recent experimental observations have extended our knowledge of trial-to-trial variability and spontaneous activity in several directions: 1. Trial-to-trial variability systematically decreases following the onset of a sensory stimulus or the start of a motor act. 2. Spontaneous activity states in sensory cortex outline the region of evoked sensory responses. 3. Across development, spontaneous activity aligns itself with typical evoked activity patterns. 4. The spontaneous brain activity prior to the presentation of an ambiguous stimulus predicts how the stimulus will be interpreted. At present it is unclear how these observations relate to each other and how they arise in cortical circuits. Here we demonstrate that all of these phenomena can be accounted for by a deterministic self-organizing recurrent neural network model (SORN, which learns a predictive model of its sensory environment. The SORN comprises recurrently coupled populations of excitatory and inhibitory threshold units and learns via a combination of spike-timing dependent plasticity (STDP and homeostatic plasticity mechanisms. Similar to balanced network architectures, units in the network show irregular activity and variable responses to inputs. Additionally, however, the SORN exhibits sequence learning abilities matching recent findings from visual cortex and the network's spontaneous activity reproduces the experimental findings mentioned above. Intriguingly, the network's behaviour is reminiscent of sampling-based probabilistic inference, suggesting that correlates of sampling-based inference can develop from the interaction of STDP and homeostasis in deterministic networks. We conclude that key observations on spontaneous brain activity and the variability of neural

  19. Design of the Control System for Engineered Safety Features of KIJANG Research Reactor

    International Nuclear Information System (INIS)

    Kim, Hagtae; Kim, Jun-Yeon; Chae, Hee-Taek

    2015-01-01

    The purpose of this paper is to design an effective control system for the Engineered Safety Features (ESF) of KJRR such as the Safety Residual Heat Removal System (SRHRS) pumps and Siphon Break Valve (SBV) without an Engineered Safety Features-Component Control System (ESF-CCS). This control system is called a 'local motor starter', because this system controls motors in the SRHRS pumps and SBVs by receiving the signal from Reactor Protection System (RPS) and Alternate Protection System (APS) when the differential pressure or pool level reach the set points. In this paper, the design concepts and requirements of the local motor starter based on the design features of KJRR is proposed. An ESF is a safety system that mitigates consequences of the Anticipated Operational Occurrence (AOO) and Design Basis Accident (DBA). The results of this paper are able to be used for the development of control systems for research reactors similar to KJRR. The precondition for such application is to have a few ESFs and conduct simple logic. The proposed control system called a local motor starter is being designed, and a manufacture of the actual systems is expected in the foreseeable future

  20. Multiple approaches to valuation of conservation design and low-impact development features in residential subdivisions.

    Science.gov (United States)

    Bowman, Troy; Tyndall, John C; Thompson, Janette; Kliebenstein, James; Colletti, Joe P

    2012-08-15

    Residents, developers and civic officials are often faced with difficult decisions about appropriate land uses in and around metropolitan boundaries. Urban expansion brings with it the potential for negative environmental impacts, but there are alternatives, such as conservation subdivision design (CSD) or low-impact development (LID), which offer the possibility of mitigating some of these effects at the development site. Many urban planning jurisdictions across the Midwest do not currently have any examples of these designs and lack information to identify public support or barriers to use of these methods. This is a case study examining consumer value for conservation and low-impact design features in one housing market by using four different valuation techniques to estimate residents' willingness to pay for CSD and LID features in residential subdivisions. A contingent valuation survey of 1804 residents in Ames, IA assessed familiarity with and perceptions of subdivision development and used an ordered value approach to estimate willingness to pay for CSD and LID features. A majority of residents were not familiar with CSD or LID practices. Residents indicated a willingness to pay for most CSD and LID features with the exception of clustered housing. Gender, age, income, familiarity with LID practices, perceptions of attractiveness of features and the perceived effect of CSD and LID features on ease of future home sales were important factors influencing residents' willingness to pay. A hypothetical referendum measured willingness to pay for tax-funded conservation land purchases and estimated that a property tax of around $50 would be the maximum increase that would pass. Twenty-seven survey respondents participated in a subsequent series of experimental real estate negotiations that used an experimental auction mechanism to estimate willingness to pay for CSD and LID features. Participants indicated that clustered housing (with interspersed preserved forest

  1. Accommodation of unprotected accidents by inherent safety design features in metallic and oxide-fueled LMFBRs

    International Nuclear Information System (INIS)

    Su, S.F.; Cahalan, J.E.; Sevy, R.H.

    1985-01-01

    This paper presents the results of a systematic study of the effectiveness of intrinsic design features to mitigate the consequences of unprotected accidents in metallic and oxide-fueled LMFBRs. The accidents analyzed belong to the class generally considered to lead to core disruption; unprotected loss-of-flow (LOF) and transient over-power (TOP). The results of the study demonstrate the potential for design features to meliorate accident consequences, and in some cases to render them benign. Emphasis is placed on the relative performance of metallic and oxide-fueled core designs, and safety margins are quantified in sensitivity studies. All analyses were carried out using the SASSYS LMFBR systems analysis code (1)

  2. The Main Shear Zone in Sør Rondane: A key feature for reconstructing the geodynamic evolution of East Antarctica

    Science.gov (United States)

    Ruppel, Antonia; Läufer, Andreas; Lisker, Frank; Jacobs, Joachim; Elburg, Marlina; Damaske, Detlef; Lucka, Nicole

    2013-04-01

    Structural investigations were carried out along the Main Shear Zone (MSZ) of western Sør Rondane (22°-25°E, 71.5°-72.5°S) to gain new information about the position of the East-/West-Gondwana suture and the ancient plate tectonic configuration during Gondwana amalgamation. The WSW-ENE striking MSZ divides south-western Sør Rondane in a northern amphibolite-facies terrane and a southern tonalite-trondhjemite-granodiorite (TTG) terrane. The structure can be traced over a distance of ca. 100 km and reaches several hundred meters in width. It is characterized by a right-lateral sense of movement and marked by a transpressional and also transtensional regime. Ductilely deformed granitoids (ca. 560 Ma: SHRIMP U-Pb of zircon) and ductile - brittle structures, which evolved in a transitional ductile to brittle regime in an undeformed syenite (ca. 499-459 Ma, Ar-Ar mica), provide a late Proterozoic/ early Paleozoic time limit for the activity of the shear zone (Shiraishi et al., 2008; Shiraishi et al., 1997). Documentation of ductile and brittle deformation allows reconstructing up to eight deformation stages. Cross-cutting relationships of structural features mapped in the field complemented by published kinematic data reveal the following relative age succession: [i] Dn+1 - formation of the main foliation during peak metamorphism, [ii] Dn+2 - isoclinal, intrafolial folding of the main foliation, mostly foliation-parallel mylonitic shear zones (1-2 meter thick), [iii] Dn+3 - formation of tight to closed folds, [iv] Dn+4 - formation of relatively upright, large-scale open folds, [v] Dn+5 - granitoid intrusion (e.g. Vengen granite), [vi] Dn+6 - dextral shearing between amphibolite and TTG terranes, formation of the MSZ, [vii] Dn+7 - intrusion of late- to post-tectonic granitoids, first stage of brittle deformation (late shearing along MSZ), intrusion of post-kinematic mafic dykes, [viii] Dn+8 - second stage of brittle deformation including formation of conjugate fault

  3. Multiple-Robot Systems for USAR: Key Design Attributes and Deployment Issues

    Directory of Open Access Journals (Sweden)

    Choon Yue Wong

    2011-03-01

    Full Text Available The interaction between humans and robots is undergoing an evolution. Progress in this evolution means that humans are close to robustly deploying multiple robots. Urban search and rescue (USAR can benefit greatly from such capability. The review shows that with state of the art artificial intelligence, robots can work autonomously but still require human supervision. It also shows that multiple robot deployment (MRD is more economical, shortens mission durations, adds reliability as well as addresses missions impossible with one robot and payload constraints. By combining robot autonomy and human supervision, the benefits of MRD can be applied to USAR while at the same time minimizing human exposure to danger. This is achieved with a single-human multiple-robot system (SHMRS. However, designers of the SHMRS must consider key attributes such as the size, composition and organizational structure of the robot collective. Variations in these attributes also induce fluctuations in issues within SHMRS deployment such as robot communication and computational load as well as human cognitive workload and situation awareness (SA. Research is essential to determine how the attributes can be manipulated to mitigate these issues while meeting the requirements of the USAR mission.

  4. Multiple-Robot Systems for USAR: Key Design Attributes and Deployment Issues

    Directory of Open Access Journals (Sweden)

    Choon Yue Wong

    2011-03-01

    Full Text Available The interaction between humans and robots is undergoing an evolution. Progress in this evolution means that humans are close to robustly deploying multiple robots. Urban search and rescue (USAR can benefit greatly from such capability. The review shows that with state of the art artificial intelligence, robots can work autonomously but still require human supervision. It also shows that multiple robot deployment (MRD is more economical, shortens mission durations, adds reliability as well as addresses missions impossible with one robot and payload constraints. By combining robot autonomy and human supervision, the benefits of MRD can be applied to USAR while at the same time minimizing human exposure to danger. This is achieved with a single-human multiple-robot system (SHMRS. However, designers of the SHMRS must consider key attributes such as the size, composition and organizational structure of the robot collective. Variations in these attributes also induce fluctuations in issues within SHMRS deployment such as robot communication and computational load as well as human cognitive workload and situation awareness (SA.Research is essential to determine how the attributes can be manipulated to mitigate these issues while meeting the requirements of the USAR mission.

  5. ALWR safety approaches and trends. Implementation of passive safety features in the design

    International Nuclear Information System (INIS)

    Ignatiev, V.

    1995-11-01

    Reactor vendors world-wide are examining various advanced light water reactors (ALWR) options to reach utility goals. The amount of information available about each design varies essentially depending on its maturity. Some advanced reactor designs are the evolutionary results of combining old structures, systems and components in new ways, others use innovative solutions. A summary review is given for better understanding of new ALWR design trends and approaches in different countries and subsequent R and D activities. An attempt was made to describe and assess specific innovative and passive features implemented in the leading ALWR designs for further plant design safety improvements. The advantages and disadvantages of these innovations in obtaining reliable systems have been considered. Also, this report indicates the importance of uncertainties remaining and identifies the additional work needed. 51 refs, 27 figs, 7 tabs

  6. ALWR safety approaches and trends. Implementation of passive safety features in the design

    Energy Technology Data Exchange (ETDEWEB)

    Ignatiev, V

    1995-11-01

    Reactor vendors world-wide are examining various advanced light water reactors (ALWR) options to reach utility goals. The amount of information available about each design varies essentially depending on its maturity. Some advanced reactor designs are the evolutionary results of combining old structures, systems and components in new ways, others use innovative solutions. A summary review is given for better understanding of new ALWR design trends and approaches in different countries and subsequent R and D activities. An attempt was made to describe and assess specific innovative and passive features implemented in the leading ALWR designs for further plant design safety improvements. The advantages and disadvantages of these innovations in obtaining reliable systems have been considered. Also, this report indicates the importance of uncertainties remaining and identifies the additional work needed. 51 refs, 27 figs, 7 tabs.

  7. Vibration isolation analysis of new design OEM damper for malaysia vehicle suspension system featuring MR fluid

    Science.gov (United States)

    Unuh, M. H.; Muhamad, P.; Norfazrina, H. M. Y.; Ismail, M. A.; Tanasta, Z.

    2018-01-01

    The applications of semi-active damper employing magnetorheological (MR) fluids keep increasing in fulfilling the demand to control undesired vibration effect. The aim of this study is to introduce the new design of damper for Malaysian vehicle model as well to evaluate its effectiveness in promoting comfort. The vibration isolation performance of the OEM damper featuring MR fluid was analysed physically under real road profile excitation experimentally. An experiment using quarter car rig suspension and LMS SCADAS Mobile was conducted to demonstrate the influence of current in controlling the characteristics of MR fluid in alter the damping behaviour under 5 cm bump impact. Subsequently, the displacement values were measured with respect to time. The new design OEM damper featuring MR fluid was validated by comparing the data with original equipment manufacturer (OEM) passive damper results under the same approach of testing. Comparison of numerical data of the new design OEM damper shown that it can reduce the excitation amplitude up to 40% compared to those obtained by OEM passive damper. Finally, the new design OEM damper featuring MR fluid has effectively isolated the disturbance from the road profile and control the output force.

  8. Design features of the radioactive Liquid-Fed Ceramic Melter system

    International Nuclear Information System (INIS)

    Holton, L.K. Jr.

    1985-06-01

    During 1983, the Pacific Northwest Laboratory (PNL), at the request of the Department of Energy (DOE), undertook a program with the principal objective of testing the Liquid-Fed Ceramic Melter (LFCM) process in actual radioactive operations. This activity, termed the Radioactive LFCM (RLFCM) Operations is being conducted in existing shielded hot-cell facilities in B-Cell of the 324 Building, 300 Area, located at Hanford, Washington. This report summarizes the design features of the RLFCM system. These features include: a waste preparation and feed system which uses pulse-agitated waste preparation tanks for waste slurry agitation and an air displacement slurry pump for transferring waste slurries to the LFCM; a waste vitrification system (LFCM) - the design features, design approach, and reasoning for the design of the LFCM are described; a canister-handling turntable for positioning canisters underneath the RLFCM discharge port; a gamma source positioning and detection system for monitoring the glass fill level of the product canisters; and a primary off-gas treatment system for removing the majority of the radionuclide contamination from the RLFCM off gas. 8 refs., 48 figs., 6 tabs

  9. Effectiveness of Runoff Control Legislation and Active, Beautiful, Clean (ABC Waters Design Features in Singapore

    Directory of Open Access Journals (Sweden)

    Xue Ping Goh

    2017-08-01

    Full Text Available Storm water management in Singapore has always been a challenge due to intense rainfall in a flat, low-lying and urbanised catchment. PUB’s (Singapore’s National Water Agency recent runoff control regulation limits the runoff coefficient to 0.55 for developments larger than or equal to 0.2 ha. The use of Active, Beautiful, Clean (ABC Waters design features are encouraged to attain peak runoff reduction. Hence the paper focuses on (i determining the actual hydrological response regime of Singapore using the relationship between runoff coefficient (C, land use and slope; and (ii investigating the effectiveness of ABC Waters design features in delaying and reducing peak runoff using a modelling approach. Based on a Storm Water Management Model (SWMM model and using elevation, land use and soil data as inputs, the peak C-values were obtained for 50 m × 50 m grid cells. The results show that for the same land use, the one with steeper slope resulted in a higher runoff coefficient. Simulations were carried out in two study areas, Green Walk District and Tengah Subcatchment, where ABC Waters design features (such as porous pavements, green roofs, rain gardens and detention tanks were incorporated to reduce C-values. Results showed that peak C-values can be reduced to less than 0.55 after increasing the green areas and constructing detention facilities. Reduction in peak discharge (22% to 63% and a delay in peak discharge by up to 30 min were also observed. Hence, it is recommended to consider the relationship between slope and land use while determining runoff coefficients; and to incorporate ABC Waters design features in urban design to reduce the peak flow and runoff coefficient (C.

  10. Mutagenicity of smoke condensates from Canadian cigarettes with different design features.

    Science.gov (United States)

    Mladjenovic, Nemanja; Maertens, Rebecca M; White, Paul A; Soo, Evelyn C

    2014-01-01

    There is currently limited knowledge regarding the impact of different cigarette designs on the toxicological properties of cigarette smoke condensate (CSC). This study used the Salmonella Mutagenicity Assay to examine the mutagenic activity of mainstream CSCs from 11 commercial Canadian cigarette brands with different design features or tobacco blend. The brands were selected to include design features that are common for cigarettes sold in the Canadian market, as well as cigarettes with alternate filters (charcoal or MicroBlue™), the super slim design, and cigarettes containing mixed blends of different tobacco types. CSCs were obtained using the International Organization for Standardization (ISO) and Health Canada Intense (HCI) smoking regimes, and mutagenic activity was assessed using Salmonella strains TA98, YG1041 and YG5185. Comparisons of the commercial brands to the Kentucky 3R4F, the Canadian Monitor 8 reference and a Canadian best seller revealed no significant reduction in CSC mutagenicity for cigarettes with alternate filters. However, the super slim design did afford some reduction in mutagenic potency. Nevertheless, since the study did not attempt to evaluate the impact of the cigarette designs on human health at the individual or population level, the super slim cigarettes cannot be considered 'reduced-harm' cigarettes.

  11. Emergent features and perceptual objects: re-examining fundamental principles in analogical display design.

    Science.gov (United States)

    Holt, Jerred; Bennett, Kevin B; Flach, John M

    2015-01-01

    Two sets of design principles for analogical visual displays, based on the concepts of emergent features and perceptual objects, are described. An interpretation of previous empirical findings for three displays (bar graph, polar graphic, alphanumeric) is provided from both perspectives. A fourth display (configural coordinate) was designed using principles of ecological interface design (i.e. direct perception). An experiment was conducted to evaluate performance (accuracy and latency of state identification) with these four displays. Numerous significant effects were obtained and a clear rank ordering of performance emerged (from best to worst): configural coordinate, bar graph, alphanumeric and polar graphic. These findings are consistent with principles of design based on emergent features; they are inconsistent with principles based on perceptual objects. Some limitations of the configural coordinate display are discussed and a redesign is provided. Practitioner Summary: Principles of ecological interface design, which emphasise the quality of very specific mappings between domain, display and observer constraints, are described; these principles are applicable to the design of all analogical graphical displays.

  12. A new design concept for offshore nuclear power plants with enhanced safety features

    International Nuclear Information System (INIS)

    Lee, Kihwan; Lee, Kang-Heon; Lee, Jeong Ik; Jeong, Yong Hoon; Lee, Phill-Seung

    2013-01-01

    Highlights: ► A new design concept for offshore nuclear power plants is proposed. ► The total general arrangement for the concept is suggested. ► A new emergency passive containment cooling system (EPCCS) is proposed. ► A new emergency passive reactor-vessel cooling system (EPRVCS) is proposed. ► Safety features against earthquakes, tsunamis, and storms are discussed. - Abstract: In this paper, we present a new concept for offshore nuclear power plants (ONPP) with enhanced safety features. The design concept of a nuclear power plant (NPP) mounted on gravity-based structures (GBSs), which are widely used offshore structures, is proposed first. To demonstrate the feasibility of the concept, a large-scale land-based nuclear power plant model APR1400, which is the most recent NPP model in the Republic of Korea, is mounted on a GBS while minimizing modification to the original features of APR1400. A new total general arrangement (GA) and basic design principles are proposed and can be directly applied to any existing land based large scale NPPs. The proposed concept will enhance the safety of a NPP due to several aspects. A new emergency passive containment cooling system (EPCCS) and emergency passive reactor-vessel cooling system (EPRVCS) are proposed; their features of using seawater as coolant and safety features against earthquakes, Tsunamis, storms, and marine collisions are also described. We believe that the proposed offshore nuclear power plant is more robust than conventional land-based nuclear power plants and it has strong potential to provide great opportunities in nuclear power industries by decoupling the site of construction and that of installation.

  13. Developing a new dental implant design and comparing its biomechanical features with four designs

    Directory of Open Access Journals (Sweden)

    Mansour Rismanchian

    2010-01-01

    Full Text Available Background: As various implant geometries present different biomechanical behaviors, the purpose of this work was to study stress distribution around tapered and cylindrical threaded implant geometries using three-dimensional finite element stress analysis. Methods : Seven implant models were constructed using Computer Assisted Designing system. After digitized models of mandibular section, the crowns were created. They were combined with implant models, which were previously imported into CATIA software. The combined solid model was transferred to ABAQOUS to create a finite element meshed model which was later analyzed regarding the highest maximum and minimum principal stresses of bone. Results: For all models, the highest stresses of cortical bone were located at the crestal cortical bone around the implant. Threaded implants, triangular thread form and taper body form showed a higher peak of tensile and compressive stress than non-threaded implants, square thread form and straight body form, respectively. A taper implant with triangular threads, which is doubled in the cervical portion of the body, had a significantly lower peak of tensile and compressive stress in the cortical bone than straight/taper triangular or square threaded implant forms. Conclusion: For the investigation of bone implant interfacial stress, the non-bonded state should be studied too. Confirmative clinical and biological studies are required in order to benefit from the results of this study.

  14. Fatigue and fail-safe design features of the DC-10 airplane

    Science.gov (United States)

    Stone, M. E.

    1972-01-01

    The philosophy and methods used in the design of the DC-10 aircraft to assure structural reliability against cracks under repeated service loads are described in detail. The approach consists of three complementary parts: (1) the structure is designed to be fatigue resistant for a crack-free life of 60,000 flight hours; (2) inasmuch as small undetected cracks could develop from other sources, such as material flaws and manufacturing preloads, the structure also is designed to arrest and control cracks within a reasonable service-inspection interval; and (3) a meaningful service-inspection program has been defined on the basis of analysis and test experience from the design development program. This service-inspection program closes the loop to assure the structural integrity of the DC-10 airframe. Selected materials, fasteners, and structural arrangements are used to achieve these design features with minimum structural weight and with economy in manufacturing and maintenance. Extensive analyses and testing were performed to develop and verify the design. The basic design considerations for fatigue-resistant structure are illustrated in terms of material selection, design loads spectra, methods for accurate stress and fatigue damage analysis, and proven concepts for efficient detail design.

  15. PIPEX - A model of a design concept for reprocessing plants with improved containment and surveillance features

    International Nuclear Information System (INIS)

    1979-03-01

    This paper explains that the PIPEX concept is essentially a reprocessing plant using the PUREX process but with in-built improved containment and surveillance features resulting in increased health protection and environmental safety as well as higher resistance to diversion of fissile material. The paper gives a general description of the design and operating philosophy of such a plant and goes on to examine the safeguards and safety principles and implications

  16. Specialists' meeting on design features affecting a dynamic behaviour of fast reactor cores. Summary report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1982-01-01

    The purpose of the meeting was to review and discuss the effects induced by changes in some design characteristics on overall performances and transient behaviour of fast reactor cores. The main topics discussed in the four technical sessions were: National Review Presentations. Identification of the key issues to be considered in the following sessions; Effects of design changes on performance characteristics. Kinetics models and codes; Evaluation and interpretation of reactivity coefficients. Kinetics calculations for restrained and free-standing cores; Comparison of the dynamic behaviour of homogeneous and heterogeneous cores.

  17. Specialists' meeting on design features affecting a dynamic behaviour of fast reactor cores. Summary report

    International Nuclear Information System (INIS)

    1982-01-01

    The purpose of the meeting was to review and discuss the effects induced by changes in some design characteristics on overall performances and transient behaviour of fast reactor cores. The main topics discussed in the four technical sessions were: National Review Presentations. Identification of the key issues to be considered in the following sessions; Effects of design changes on performance characteristics. Kinetics models and codes; Evaluation and interpretation of reactivity coefficients. Kinetics calculations for restrained and free-standing cores; Comparison of the dynamic behaviour of homogeneous and heterogeneous cores

  18. Design Features in Games for Health: Disciplinary and Interdisciplinary Expert Perspectives.

    Science.gov (United States)

    Kelley, Christina; Wilcox, Lauren; Ng, Wendy; Schiffer, Jade; Hammer, Jessica

    2017-06-01

    Games for health (G4H) aim to improve health outcomes and encourage behavior change. While existing theoretical frameworks describe features of both games and health interventions, there has been limited systematic investigation into how disciplinary and interdisciplinary stakeholders understand design features in G4H. We recruited 18 experts from the fields of game design, behavioral health, and games for health, and prompted them with 16 sample games. Applying methods including open card sorting and triading, we elicited themes and features (e.g., real-world interaction, game mechanics) around G4H. We found evidence of conceptual differences suggesting that a G4H perspective is not simply the sum of game and health perspectives. At the same time, we found evidence of convergence in stakeholder views, including areas where game experts provided insights about health and vice versa. We discuss how this work can be applied to provide conceptual tools, improve the G4H design process, and guide approaches to encoding G4H-related data for large-scale empirical analysis.

  19. Cigarette Design Features: Effects on Emission Levels, User Perception, and Behavior.

    Science.gov (United States)

    Talhout, Reinskje; Richter, Patricia A; Stepanov, Irina; Watson, Christina V; Watson, Clifford H

    2018-01-01

    This paper describes the effects of non-tobacco, physical cigarette design features on smoke emissions, product appeal, and smoking behaviors - 3 factors that determine smoker's exposure and related health risks. We reviewed available evidence for the impact of filter ventilation, new filter types, and cigarettes dimensions on toxic emissions, smoker's perceptions, and behavior. For evidence sources we used scientific literature and websites providing product characteristics and marketing information. Whereas filter ventilation results in lower machine-generated emissions, it also leads to perceptions of lighter taste and relative safety in smokers who can unwittingly employ more intense smoking behavior to obtain the desired amount of nicotine and sensory appeal. Filter additives that modify smoke emissions can also modify sensory cues, resulting in changes in smoking behavior. Flavor capsules increase the cigarette's appeal and novelty, and lead to misperceptions of reduced harm. Slim cigarettes have lower yields of some smoke emissions, but smoking behavior can be more intense than with standard cigarettes. Physical design features significantly impact machine-measured emission yields in cigarette smoke, product appeal, smoking behaviors, and exposures in smokers. The influence of current and emerging design features is important in understanding the effectiveness of regulatory actions to reduce smoking-related harm.

  20. Exploring Socio-Technical Features of Green Interior Design of Residential Buildings: Indicators, Interdependence and Embeddedness

    Directory of Open Access Journals (Sweden)

    Yan Ning

    2016-12-01

    Full Text Available This research aims to develop indicators for assessing green interior design of new residential buildings in China, grounded in the socio-technical systems approach. The research was carried out through a critical literature review and two focus group studies. The results show that the boundaries of green interior design were identified with respect to three dimensions, namely performance, methodology and stakeholders. The socio-technical systems approach argues for the recognition of the interdependence between the systems elements and the feature of embeddedness. The interdependence of the systems elements exists within each of these three dimensions and across them. It is also found that the socio-technical systems of green interior design are embedded in the social, regulatory and geographic context. Taking interior design of residential buildings as the empirical setting, this study contributes to the literature of green building assessment by presenting a socio-technical systems approach.

  1. Development of quantitative goals for inherent safety feature design and licensing

    International Nuclear Information System (INIS)

    Kastenberg, W.E.; Apostolakis, G.; Dhir, V.K.; Okrent, D.

    1987-01-01

    There is now considerable interest in the development of advanced fast reactors whose major focus is inherent safety. The achievement of inherent safety can be viewed from several aspects. In the Integral Fast Reactor Concept the approach is to utilize the intrinsic characteristics of pool-type liquid metal fast breeder reactors (LMFBRs) and the properties of metal fuels to integrate a high degree of inherent safety into the design. The PRISM and SAFR concepts focus on other inherent safety features. The reactors discussed above represent a radical departure from existing LWR designs as well as previous LMFBR designs (e.g., CRBRP) which are based, for the most part, on the General Design Criteria found in 10CFR50 Appendix. In view of these parallel developments (advanced reactors exploiting inherent safety and the use of quantitative goals to augment licensing), there appears to be a need to perform research on the development of methods for designing, assessing, and licensing inherent safety features in advanced reactors. The objectives of such research are outlined

  2. The SSB-positive/SSA-negative antibody profile is not associated with key phenotypic features of Sjögren's syndrome

    DEFF Research Database (Denmark)

    Baer, Alan N; McAdams DeMarco, Mara; Shiboski, Stephen C

    2015-01-01

    phenotypic features. Among SICCA participants classified with SS on the basis of the American-European Consensus Group or American College of Rheumatology criteria, only 2% required the anti-SSB-alone test result to meet these criteria. CONCLUSIONS: The presence of anti-SSB, without anti-SSA antibodies, had...... participants, 2061 (63%) had negative anti-SSA/anti-SSB, 1162 (35%) had anti-SSA with or without anti-SSB, and 74 (2%) anti-SSB alone. Key SS phenotypic features were more prevalent and had measures indicative of greater disease activity in those participants with anti-SSA, either alone or with anti-SSB, than...... in those with anti-SSB alone or negative SSA/SSB serology. These between-group differences were highly significant and not explained by confounding by age, race/ethnicity or gender. Participants with anti-SSB alone were comparable to those with negative SSA/SSB serology in their association with these key...

  3. Key features of wave energy.

    Science.gov (United States)

    Rainey, R C T

    2012-01-28

    For a weak point source or dipole, or a small body operating as either, we show that the power from a wave energy converter (WEC) is the product of the particle velocity in the waves, and the wave force (suitably defined). There is a thus a strong analogy with a wind or tidal turbine, where the power is the product of the fluid velocity through the turbine, and the force on it. As a first approximation, the cost of a structure is controlled by the force it has to carry, which governs its strength, and the distance it has to be carried, which governs its size. Thus, WECs are at a disadvantage compared with wind and tidal turbines because the fluid velocities are lower, and hence the forces are higher. On the other hand, the distances involved are lower. As with turbines, the implication is also that a WEC must make the most of its force-carrying ability-ideally, to carry its maximum force all the time, the '100% sweating WEC'. It must be able to limit the wave force on it in larger waves, ultimately becoming near-transparent to them in the survival condition-just like a turbine in extreme conditions, which can stop and feather its blades. A turbine of any force rating can achieve its maximum force in low wind speeds, if its diameter is sufficiently large. This is not possible with a simple monopole or dipole WEC, however, because of the 'nλ/2π' capture width limits. To achieve reasonable 'sweating' in typical wave climates, the force is limited to about 1 MN for a monopole device, or 2 MN for a dipole. The conclusion is that the future of wave energy is in devices that are not simple monopoles or dipoles, but multi-body devices or other shapes equivalent to arrays.

  4. Development of advanced design features for KNGR reactor vessel and internals

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jong Kyun; Ru, Bong; Lee, Jae Han; Lee, Hyung Yeon; Kim, Jong Bum; Ku, Kyung Heoy; Lee, Ki Young; Lee, Jun; Kim, Young In [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1995-12-01

    Developments of KNGR design require to enhance the design to implement the design requirements, such as plant life time from 40 years to 60 years, safety, performance and structure and components design. The designs used for existing nuclear power plants should be modified or improved to meet the requirements in KNGR design. The purpose of the task is to develop the Advanced Design Features (ADF) related to mechanical and structural design for KNGR reactor vessel and reactor internals. The structural integrity for the System 80+ reactor vessel, of which design life is 60 years, was reviewed. EPRI-URD, CESSAR-DC, and the present design status and characteristics of System 80+ reactor vessel were comparatively studied and the improvement of reactor vessel surveillance program was investigated. The performance and aseismic characteristics of the CE-type CEDM, which will be used in System 80+, are investigated. The driving cycles of CEDM are evaluated for the load follow operation(LFO), of which Mode K is being developed by KAERI. The position of the USNRC, EPRI, ABB-CE, and industries on the elimination of OBE are reviewed, and especially ABB-CE System 80+ FSER is reviewed in detail. For the pre-stage of the verification of the OBE elimination from the design, the review of the seismic responses, i.e.. shear forces and moments, of YGN 3/4 RI was performed and the ratio of OBE response to SSE response was analysed. The screening criteria were reviewed to evaluate the integrity against pressurized thermal shock (PTS) for RV belt-line of System 80+. The evaluation methods for fracture integrity when screening criteria are not met were reviewed. The structural characteristics of IRWST spargers of System 80+ were investigated and the effect of hydrodynamic loads on NSSS was reviewed. 18 figs., 9 tabs., 40 refs. (Author) .new.

  5. Development of advanced design features for KNGR reactor vessel and internals

    International Nuclear Information System (INIS)

    Park, Jong Kyun; Ru, Bong; Lee, Jae Han; Lee, Hyung Yeon; Kim, Jong Bum; Ku, Kyung Heoy; Lee, Ki Young; Lee, Jun; Kim, Young In

    1995-12-01

    Developments of KNGR design require to enhance the design to implement the design requirements, such as plant life time from 40 years to 60 years, safety, performance and structure and components design. The designs used for existing nuclear power plants should be modified or improved to meet the requirements in KNGR design. The purpose of the task is to develop the Advanced Design Features (ADF) related to mechanical and structural design for KNGR reactor vessel and reactor internals. The structural integrity for the System 80+ reactor vessel, of which design life is 60 years, was reviewed. EPRI-URD, CESSAR-DC, and the present design status and characteristics of System 80+ reactor vessel were comparatively studied and the improvement of reactor vessel surveillance program was investigated. The performance and aseismic characteristics of the CE-type CEDM, which will be used in System 80+, are investigated. The driving cycles of CEDM are evaluated for the load follow operation(LFO), of which Mode K is being developed by KAERI. The position of the USNRC, EPRI, ABB-CE, and industries on the elimination of OBE are reviewed, and especially ABB-CE System 80+ FSER is reviewed in detail. For the pre-stage of the verification of the OBE elimination from the design, the review of the seismic responses, i.e.. shear forces and moments, of YGN 3/4 RI was performed and the ratio of OBE response to SSE response was analysed. The screening criteria were reviewed to evaluate the integrity against pressurized thermal shock (PTS) for RV belt-line of System 80+. The evaluation methods for fracture integrity when screening criteria are not met were reviewed. The structural characteristics of IRWST spargers of System 80+ were investigated and the effect of hydrodynamic loads on NSSS was reviewed. 18 figs., 9 tabs., 40 refs. (Author) .new

  6. Influence of design features on decommissioning of a large fast breeder reactor

    International Nuclear Information System (INIS)

    Fournie, J.-L.; Alary, C.; Maire, D.; Seroux, N. de; Peyrard, G.

    1990-01-01

    The evolution of FBR design in Europe shows that pool-type design will become the reference design for future FBR and the projected European Fast Reactor (EFR) is based on this concept. The identification of design features shows that the main contributors of the sodium and structures activity are the Co60 for gamma radiation source and low decay, Ni63, Nb94 and Ni59 for long time decay. So, the technical benefits of a Co content reduction are interesting for the high activated structures and for diagrid thimbles coating and we made proposals to lower Co content in steels or alloys and to substitute coatings. We identify measures which must facilitate both the sodium draining and the reactor block and internal cleaning: all which improve the gravity draining and the downing of the sodium flow make easier the penetration of cleaning products. The features, connected with the dismantling of the very activated internal structures, of the roof and of the lay-out, are mentioned. (author)

  7. Green Infrastructure Design Based on Spatial Conservation Prioritization and Modeling of Biodiversity Features and Ecosystem Services.

    Science.gov (United States)

    Snäll, Tord; Lehtomäki, Joona; Arponen, Anni; Elith, Jane; Moilanen, Atte

    2016-02-01

    There is high-level political support for the use of green infrastructure (GI) across Europe, to maintain viable populations and to provide ecosystem services (ES). Even though GI is inherently a spatial concept, the modern tools for spatial planning have not been recognized, such as in the recent European Environment Agency (EEA) report. We outline a toolbox of methods useful for GI design that explicitly accounts for biodiversity and ES. Data on species occurrence, habitats, and environmental variables are increasingly available via open-access internet platforms. Such data can be synthesized by statistical species distribution modeling, producing maps of biodiversity features. These, together with maps of ES, can form the basis for GI design. We argue that spatial conservation prioritization (SCP) methods are effective tools for GI design, as the overall SCP goal is cost-effective allocation of conservation efforts. Corridors are currently promoted by the EEA as the means for implementing GI design, but they typically target the needs of only a subset of the regional species pool. SCP methods would help to ensure that GI provides a balanced solution for the requirements of many biodiversity features (e.g., species, habitat types) and ES simultaneously in a cost-effective manner. Such tools are necessary to make GI into an operational concept for combating biodiversity loss and promoting ES.

  8. Some novel design features of the LBL metal vapor vacuum arc ion sources

    International Nuclear Information System (INIS)

    MacGill, R.A.; Brown, I.G.; Galvin, J.E.

    1990-01-01

    The family of MEVVA (metal vapor vacuum arc) high current metal ion sources developed at LBL over the past several years has grown to include a number of different source versions with a wide range of some of the design and operational parameters. The MicroMEVVA source is a particularly compact version, about 2 cm diam and 10 cm long, while the MEVVA IV weighs some 30 kG. MEVVAs IV and V incorporate multiple cathode assemblies (16 and 18 separate cathodes, respectively), and the operating cathode can be switched rapidly and without downtime. The new MEVVA V embodiment is quite compact considering its broad beam (10 cm), high voltage (100 kV), and multiple cathode features. The large-area extractor grids used in MEVVA V were fabricated using a particularly simple technique, and they are clamped into position and can thus be changed simply and quickly. The electrical system used to drive the arc is particularly simple and incorporates several attractive features. In this article we review and describe a number of the mechanical and electrical design features that have been developed for these sources

  9. Acoustical features of two Mayan monuments at Chichen Itza: Accident or design?

    Science.gov (United States)

    Lubman, David

    2002-11-01

    Chichen Itza dominated the early postclassic Maya world, ca. 900-1200 C.E. Two of its colossal monuments, the Great Ball Court and the temple of Kukulkan, reflect the sophisticated, hybrid culture of a Mexicanized Maya civilization. The architecture seems intended for ceremony and ritual drama. Deducing ritual practices will advance the understanding of a lost civilization, but what took place there is largely unknown. Perhaps acoustical science can add value. Unexpected and unusual acoustical features can be interpreted as intriguing clues or irrelevant accidents. Acoustical advocates believe that, when combined with an understanding of the Maya worldview, acoustical features can provide unique insights into how the Maya designed and used theater spaces. At Chichen Itza's monuments, sound reinforcement features improve rulers and priests ability to address large crowds, and Ball Court whispering galleries permit speech communication over unexpectedly large distances. Handclaps at Kukulkan stimulate chirps that mimic a revered bird (''Kukul''), thus reinforcing cultic beliefs. A ball striking playing field wall stimulates flutter echoes at the Great Ball Court; their strength and duration arguably had dramatic, mythic, and practical significance. Interpretations of the possible mythic, magic, and political significance of sound phenomena at these Maya monuments strongly suggests intentional design.

  10. Dental Implant Macro-Design Features Can Impact the Dynamics of Osseointegration.

    Science.gov (United States)

    Vivan Cardoso, Marcio; Vandamme, Katleen; Chaudhari, Amol; De Rycker, Judith; Van Meerbeek, Bart; Naert, Ignace; Duyck, Joke

    2015-08-01

    The purpose of this study was to compare the clinical performance of two dental implant types possessing a different macro-design in the in vivo pig model. Titanium Aadva(TM) implants (GC, Tokyo, Japan) were compared with OsseoSpeed(TM) implants (Astra, Mölndal, Sweden), with the Aadva implant displaying significant larger inter-thread dimensions than the OsseoSpeed implant. Implants were installed in the parietal bone of 12 domestic pigs and left for healing for either 1 or 3 months. Implant osseointegration was evaluated by quantitative histology (bone volume relative to the tissue volume [BV/TV]; bone-to-implant contact [BIC]) for distinct implant regions (collar, body, total implant length) with specific implant thread features. The Wilcoxon-Mann-Whitney nonparametric test with α = 0.05 was performed. An inferior amount of bone enveloping the Aadva implant compared with the OsseoSpeed implant was observed, in particular at the implant body part with its considerable inter-thread gaps (p macro-design negatively affected the amount of bone in direct contact with the implant for this specific implant part (p implant osseointegration at the initial healing stage (total implant length; 1-month healing; p implant displayed a clinically acceptable level of osseointegration, the findings demonstrate that implant macro-design features can impact the dynamics of implant osseointegration. Consideration of specific implant macro-design features should be made relative to the biological and mechanical microenvironment. © 2013 Wiley Periodicals, Inc.

  11. Cost reduction and safety design features of ABWR-II. Annex 5

    International Nuclear Information System (INIS)

    Koh, F.; Moriya, K.; Anegawa, T.

    2002-01-01

    The ABWR-II, which is aimed to be the next generation reactor following the latest BWR: Advanced Boiling Reactor (ABWR), is now under development jointly by the Japanese BWR utilities, General Electric Company, Hitachi Limited, and Toshiba Corporation. The key objectives of ABWR-II development include improvement in economics and further sophistication in safety for commercialization in the late 2010's and after. This paper summarizes the current status of ABWR-II development focusing on economics and safety. Plant power rating, fuel size, CRD rationalization and outage period are discussed from a cost reduction perspective. In terms of safety, the features such as diversification in emergency power sources and passive system application against severe accidents are being introduced. (author)

  12. Upgradation of design features of primary coolant pumps of Indian 220 MWe PHWR

    International Nuclear Information System (INIS)

    Sharma, S.S.; Mhetre, S.G.; Manna, M.M.

    1994-01-01

    Evolution in the design features of Primary Coolant Pump (PCP) had started in fifties for catering to stringent specification requirements of reactor coolant systems of larger capacity reactors of various kinds. Primary coolant pumps of PWR and PHWR are employed for circulating radioactive, pressurized hot water in a circuit consisting of reactor (heat source) and steam generator (heat sink). As primary coolant pump capacity decides the station capacity, larger capacity primary coolant pumps have been evolved. Since primary coolant pump pressure containing parts are part of Primary Heat Transport system envelope, the parts are designed, manufactured, inspected and tested in accordance with the applicable system guidelines. Flywheel is mounted on the motor shaft for increasing mass moment of inertia of pump motor rotor to meet the coast down requirements of reactor cooling system under Class-IV electrical power supply failure. Due to limited accessibility of the PCP (PCP installed in shut down accessible area), quick maintenance, condition monitoring, reliable shaft seal system/bearing system aspects have been of great concern to reactor owners and pump manufacturers. In this paper upgradation of design features of RAPS, MAPS and NAPS primary coolant pumps have been covered. (author). 4 figs., 1 tab

  13. Design-Based Comparison of Spine Surgery Simulators: Optimizing Educational Features of Surgical Simulators.

    Science.gov (United States)

    Ryu, Won Hyung A; Mostafa, Ahmed E; Dharampal, Navjit; Sharlin, Ehud; Kopp, Gail; Jacobs, W Bradley; Hurlbert, R John; Chan, Sonny; Sutherland, Garnette R

    2017-10-01

    Simulation-based education has made its entry into surgical residency training, particularly as an adjunct to hands-on clinical experience. However, one of the ongoing challenges to wide adoption is the capacity of simulators to incorporate educational features required for effective learning. The aim of this study was to identify strengths and limitations of spine simulators to characterize design elements that are essential in enhancing resident education. We performed a mixed qualitative and quantitative cohort study with a focused survey and interviews of stakeholders in spine surgery pertaining to their experiences on 3 spine simulators. Ten participants were recruited spanning all levels of training and expertise until qualitative analysis reached saturation of themes. Participants were asked to perform lumbar pedicle screw insertion on 3 simulators. Afterward, a 10-item survey was administrated and a focused interview was conducted to explore topics pertaining to the design features of the simulators. Overall impressions of the simulators were positive with regards to their educational benefit, but our qualitative analysis revealed differing strengths and limitations. Main design strengths of the computer-based simulators were incorporation of procedural guidance and provision of performance feedback. The synthetic model excelled in achieving more realistic haptic feedback and incorporating use of actual surgical tools. Stakeholders from trainees to experts acknowledge the growing role of simulation-based education in spine surgery. However, different simulation modalities have varying design elements that augment learning in distinct ways. Characterization of these design characteristics will allow for standardization of simulation curricula in spinal surgery, optimizing educational benefit. Copyright © 2017 Elsevier Inc. All rights reserved.

  14. Deep nets vs expert designed features in medical physics: An IMRT QA case study.

    Science.gov (United States)

    Interian, Yannet; Rideout, Vincent; Kearney, Vasant P; Gennatas, Efstathios; Morin, Olivier; Cheung, Joey; Solberg, Timothy; Valdes, Gilmer

    2018-03-30

    The purpose of this study was to compare the performance of Deep Neural Networks against a technique designed by domain experts in the prediction of gamma passing rates for Intensity Modulated Radiation Therapy Quality Assurance (IMRT QA). A total of 498 IMRT plans across all treatment sites were planned in Eclipse version 11 and delivered using a dynamic sliding window technique on Clinac iX or TrueBeam Linacs. Measurements were performed using a commercial 2D diode array, and passing rates for 3%/3 mm local dose/distance-to-agreement (DTA) were recorded. Separately, fluence maps calculated for each plan were used as inputs to a convolution neural network (CNN). The CNNs were trained to predict IMRT QA gamma passing rates using TensorFlow and Keras. A set of model architectures, inspired by the convolutional blocks of the VGG-16 ImageNet model, were constructed and implemented. Synthetic data, created by rotating and translating the fluence maps during training, was created to boost the performance of the CNNs. Dropout, batch normalization, and data augmentation were utilized to help train the model. The performance of the CNNs was compared to a generalized Poisson regression model, previously developed for this application, which used 78 expert designed features. Deep Neural Networks without domain knowledge achieved comparable performance to a baseline system designed by domain experts in the prediction of 3%/3 mm Local gamma passing rates. An ensemble of neural nets resulted in a mean absolute error (MAE) of 0.70 ± 0.05 and the domain expert model resulted in a 0.74 ± 0.06. Convolutional neural networks (CNNs) with transfer learning can predict IMRT QA passing rates by automatically designing features from the fluence maps without human expert supervision. Predictions from CNNs are comparable to a system carefully designed by physicist experts. © 2018 American Association of Physicists in Medicine.

  15. Key influences in the design and implementation of mental health information systems in Ghana and South Africa.

    Science.gov (United States)

    Ahuja, S; Mirzoev, T; Lund, C; Ofori-Atta, A; Skeen, S; Kufuor, A

    2016-01-01

    Strengthening of mental health information systems (MHIS) is essential to monitor and evaluate mental health services in low and middle-income countries. While research exists assessing wider health management information systems, there is limited published evidence exploring the design and implementation of MHIS in these settings. This paper aims to identify and assess the key factors affecting the design and implementation of MHIS, as perceived by the key stakeholders in Ghana and South Africa. We report findings from the Mental Health and Poverty Project, a 5-year research programme implemented within four African countries. The MHIS strengthening in South Africa and Ghana included two related components: intervention and research. The intervention component aimed to strengthen MHIS in the two countries, and the research component aimed to document interventions in each country, including the key influences. Data were collected using semi structured interviews with key stakeholders and reviews of key documents and secondary data from the improved MHIS. We analyzed the qualitative data using a framework approach. Key components of the MHIS intervention involved the introduction of a redesigned patient registration form, entry into computers for analysis every 2 months by clinical managerial staff, and utilization of data in hospital management meetings in three psychiatric hospitals in Ghana; and the introduction of a new set of mental health indicators and related forms and tally sheets at primary care clinics and district hospitals in five districts in the KwaZulu-Natal and Northern Cape provinces in South Africa. Overall, the key stakeholders perceived the MHIS strengthening as an effective intervention in both countries with an enhanced set of indicators in South Africa and introduction of a computerized system in Ghana. Influences on the design and implementation of MHIS interventions in Ghana and South Africa relate to resources, working approaches

  16. Design Features and Capabilities of the First Materials Science Research Rack

    Science.gov (United States)

    Pettigrew, P. J.; Lehoczky, S. L.; Cobb, S. D.; Holloway, T.; Kitchens, L.

    2003-01-01

    The First Materials Science Research Rack (MSRR-1) aboard the International Space Station (ISS) will offer many unique capabilities and design features to facilitate a wide range of materials science investigations. The initial configuration of MSRR-1 will accommodate two independent Experiment Modules (EMS) and provide the capability for simultaneous on-orbit processing. The facility will provide the common subsystems and interfaces required for the operation of experiment hardware and accommodate telescience capabilities. MSRR1 will utilize an International Standard Payload Rack (ISPR) equipped with an Active Rack Isolation System (ARIS) for vibration isolation of the facility.

  17. Design features and operating experiences of neutron measurement system for HANARO

    International Nuclear Information System (INIS)

    Kim, Young Ki; Choi, Young San

    1999-02-01

    This paper discusses unique mechanical and electrical design features of neutron measurement system for HANARO and its operating experiences. Some unexpected problems and misbehaviors during installation and commissioning are briefly introduced. Engineering approaches and procedures in order to solve the problems we are described in priority. It has been proved, through years of operation that the wide range neutron measurement system for HANARO has a good capability of providing the stable and reliable neutron flux signal for reactor control and reactor protection. I hopefully expect that the engineering solutions suggested in this report could be a good reference to the other applications. (Author). 12 refs., 6 tabs., 23 figs

  18. Design features of isotope production facility at Inshas cyclotron complex. Vol. 1

    Energy Technology Data Exchange (ETDEWEB)

    Comsan, M N [Nuclear Research Center, Atomic Energy Aurhority, Cairo, (Egypt)

    1996-03-01

    The nuclear research center, AEA, Egypt is erecting at its Inshas campus cyclotron complex for multidisciplinary use for research and application. The complex is to utilize a russian made AVF cyclotron accelerator of the type MGC-20 with MeV protons. Among its applications, the accelerator will be used for the production of short lived cyclotron isotopes. This article presents a concise description of the design features of isotope production facility to be annexed to the complex layout, schemes for radio waste, ventilation, and air conditioning systems. 2 figs., 2 tabs.

  19. Cryptographic analysis on the key space of optical phase encryption algorithm based on the design of discrete random phase mask

    Science.gov (United States)

    Lin, Chao; Shen, Xueju; Li, Zengyan

    2013-07-01

    The key space of phase encryption algorithm using discrete random phase mask is investigated by numerical simulation in this paper. Random phase mask with finite and discrete phase levels is considered as the core component in most practical optical encryption architectures. The key space analysis is based on the design criteria of discrete random phase mask. The role of random amplitude mask and random phase mask in optical encryption system is identified from the perspective of confusion and diffusion. The properties of discrete random phase mask in a practical double random phase encoding scheme working in both amplitude encoding (AE) and phase encoding (PE) modes are comparably analyzed. The key space of random phase encryption algorithm is evaluated considering both the encryption quality and the brute-force attack resistibility. A method for enlarging the key space of phase encryption algorithm is also proposed to enhance the security of optical phase encryption techniques.

  20. Virtual communities, research groups and projects on IMS Learning Design. State of the art, key factors and forthcoming challenges

    NARCIS (Netherlands)

    Burgos, Daniel; Koper, Rob

    2005-01-01

    Burgos, D., Koper, R. (2005) Virtual communities, research groups and projects on IMS Learning Design. State of the art, key factors and forthcoming challenges. In E-Journal of Educational Research, Assessment and Evaluation, vol. 11, issue 2 [www.uv.es/RELIEVE]. Available at

  1. The Sanford Science Education Center: Addressing Key Design Challenges in Sharing Complex Science with Diverse Audiences

    Science.gov (United States)

    Inverness Research, 2016

    2016-01-01

    In facilities throughout the United States and abroad, communities of scientists share infrastructure, instrumentation, and equipment to conduct scientific research. In these large facilities--laboratories, accelerators, telescope arrays, and research vessels--scientists are researching key questions that have the potential to make a significant…

  2. Design of free patterns of nanocrystals with ad hoc features via templated dewetting

    Energy Technology Data Exchange (ETDEWEB)

    Aouassa, M.; Berbezier, I.; Favre, L.; Ronda, A. [IM2NP, CNRS, AMU, Marseille (France); Bollani, M.; Sordan, R. [LNES, Como (Italy); Delobbe, A.; Sudraud, P. [Orsay Physics, Fuveau (France)

    2012-07-02

    Design of monodisperse ultra-small nanocrystals (NCs) into large scale patterns with ad hoc features is demonstrated. The process makes use of solid state dewetting of a thin film templated through alloy liquid metal ion source focused ion beam (LMIS-FIB) nanopatterning. The solid state dewetting initiated at the edges of the patterns controllably creates the ordering of NCs with ad hoc placement and periodicity. The NC size is tuned by varying the nominal thickness of the film while their position results from the association of film retraction from the edges of the lay out and Rayleigh-like instability. The use of ultra-high resolution LMIS-FIB enables to produce monocrystalline NCs with size, periodicity, and placement tunable as well. It provides routes for the free design of nanostructures for generic applications in nanoelectronics.

  3. DEVELOPMENT OF EDUCATION AND INFORMATION PORTAL OF PHYSICS ACADEMIC COURSE: WEB DESIGN FEATURES

    Directory of Open Access Journals (Sweden)

    Іryna A. Slipukhina

    2018-04-01

    Full Text Available The purpose of this article is to present the main components and features of designing an educational and informational portal for students. Selection of personal trajectory is realized through the use of personal account, which includes electronic laboratory reports, information materials on studying progress, means of communication with a teacher, etc. The created portal allows the administrator to easily monitor and check laboratory reports, keep an e-journal with grades. To develop the website design, functional modules and components, the Adobe Photoshop ™ environment was used, as well as the HTML and CSS layout of the web portal. The modern Bootstrap technology was applied to adapt the web page interface. The didactic opportunities of using this portal as a part of personalization process in teaching physics were considered.

  4. New design of engineered safety features-component control system to improve performance and reliability

    International Nuclear Information System (INIS)

    Kim, S.T.; Jung, H.W.; Lee, S.J.; Cho, C.H.; Kim, D.H.; Kim, H.

    2006-01-01

    Full text: Full text: The Engineered Safety Features-Component Control System (ESF-CCS) controls the engineered safety features of a Nuclear Power Plant such as Solenoid Operated Valves (SOV), Motor Operated Valves (MOV), pumps, dampers, etc. to mitigate the effects of a Design Basis Accident (DBA) or an abnormal operation. ESF-CCS serves as an interface system between the Plant Protection System (PPS) and remote actuation devices. ESF-CCS is composed of fault tolerant Group Controllers GC, Loop Controllers (LC), ESF-CCS Test and Interface Processor (ETIP) and Cabinet Operator Module (COM) and Control Channel Gateway (CCG) etc. GCs in each division are designed to be fully independent triple configuration, which perform system level NSSS and BOP ESFAS logic (2-out-of-4 logic and l-out-of-2 logic, respectively) making it possible to test each GC individually during normal operation. In the existing configuration, the safety-related plant component control is part of the Plant Control System (PCS) non-safety system. For increased safety and reliability, this design change incorporates this part into the LCs, and is therefore designed according to the safety-critical system procedures. The test and diagnosis capabilities of ETIP and COM are reinforced. By means of an automatic periodic test for all main functions of the system, it is possible to quickly determine an abnormal status of the system, and to decrease the elapsed time for tests, thus effectively increasing availability. ESF-CCS consists of four independent divisions (A, B, C, and D) in the Advanced Power Reactor 1400 (APR1400). One prototype division is being manufactured and will be tested

  5. Design and marketing features influencing choice of e-cigarettes and tobacco in the EU.

    Science.gov (United States)

    Laverty, Anthony A; Vardavas, Constantine I; Filippidis, Filippos T

    2016-10-01

    Data were analysed from the 2014 Special Eurobarometer for Tobacco survey. We estimated self-rated importance of various factors in the choice of both tobacco and electronic cigarettes (e-cigarettes) among tobacco smokers who had ever used an e-cigarette. Among ever users of tobacco and e-cigarettes (N = 2430), taste (39.4%), price (39.2%) and amount of nicotine (27.3%) were the most commonly cited reasons for choosing their brand of e-cigarettes. Those aged 15-24 were more likely to cite external packaging [adjusted prevalence ratio (aPR = 2.06, 95% CI 1.00-4.23)] and design features (aPR = 1.99, 1.20-3.29) as important. As further legislation is debated and enacted enhanced regulation of price, design and marketing features of e-cigarettes may help to reduce the appeal of e-cigarettes. © The Author 2016. Published by Oxford University Press on behalf of the European Public Health Association.

  6. Language Evolution: Why Hockett's Design Features are a Non-Starter.

    Science.gov (United States)

    Wacewicz, Sławomir; Żywiczyński, Przemysław

    The set of design features developed by Charles Hockett in the 1950s and 1960s remains probably the most influential means of juxtaposing animal communication with human language. However, the general theoretical perspective of Hockett is largely incompatible with that of modern language evolution research. Consequently, we argue that his classificatory system-while useful for some descriptive purposes-is of very limited use as a theoretical framework for evolutionary linguistics. We see this incompatibility as related to the ontology of language, i.e. deriving from Hockett's interest in language as a product rather than a suite of sensorimotor, cognitive and social abilities that enable the use but also acquisition of language by biological creatures (the faculty of language ). After a reconstruction of Hockett's views on design features, we raise two criticisms: focus on the means at the expense of content and focus on the code itself rather than the cognitive abilities of its users . Finally, referring to empirical data, we illustrate some of the problems resulting from Hockett's approach by addressing three specific points-namely arbitrariness and semanticity , cultural transmission , and displacement -and show how the change of perspective allows to overcome those difficulties.

  7. Creativity as a Key Driver for Designing Context Sensitive Health Informatics.

    Science.gov (United States)

    Zhou, Chunfang; Nøhr, Christian

    2017-01-01

    In order to face the increasing challenges of complexity and uncertainty in practice of health care, this paper aims to discuss how creativity can contribute to design new technologies in health informatics systems. It will firstly introduce the background highlighting creativity as a missing element in recent studies on context sensitive health informatics. Secondly, the concept of creativity and its relationship with activities of technology design will be discussed from a socio-culture perspective. This will be thirdly followed by understanding the roles of creativity in designing new health informatics technologies for meeting needs of high context sensitivity. Finally, a series of potential strategies will be suggested to improve creativity among technology designers working in healthcare industries. Briefly, this paper innovatively bridges two areas studies on creativity and context sensitive health informatics by issues of technology design that also indicates its important significances for future research.

  8. Westinghouse integrated protection system. An overview of the software design and maintenance features

    International Nuclear Information System (INIS)

    Gibson, R.J.

    1995-01-01

    The Westinghouse Integrated Protection System was designed with the goal of providing a system which can be easily verified, validated, and maintained. The software design and structure promote the ease of translation from functional requirements to applications function software while also improving the ability to verify and maintain the applications function software. The use of independent, reusable, common functions software modules focuses the design, verification, and validation of the software and reduces the likelihood of errors occurring during the application and maintenance of the software. The simple continuous loop method of operation used throughout the IPS provides a standard deterministic method of operation. The IPS design also incorporates the use of embedded self-diagnostics to perform continuous hardware oriented tests of the system and the use of an independent subsystem to automatically perform a functional test of the system. Maintenance interfaces also exist to readily identify and locate faults as well as providing other maintenance capabilities. These testing and maintenance features enhance the overall reliability and availability of the system. (orig.) (2 refs., 2 figs.)

  9. Noble metals-compatible melter features development Phase 1: Establishing functional and design criteria and design concepts

    International Nuclear Information System (INIS)

    Elmore, M.R.; Siemens, D.H.; Chapman, C.C.

    1996-03-01

    Premature failures have occurred in melters at Japan's Tokai Mockup Facility and at the Federal Republic of Germany (FRG) PAMELA plant during processing of feeds with high levels of noble metals. Melter failure was due to the accumulation of an electrically conductive, noble metals-containing precipitates in the glass, that then resulted in short circuiting of the electrodes. A comparison was made of the anticipated Hanford Waste Vitrification Plant (HWVP) feed with the feeds processed in the FRG and Japanese melters. The evaluation showed that comparable levels of noble metals and other potential precipitate-forming components (e.g. Cr/Fe/Ni-spinels) exist in the HWVP feed. As a result, the HWVP project made a decision to modify the present reference melter design to include features to prevent the precipitation and accumulation or otherwise accommodate precipitated phases on a routine basis without loss of production capacity

  10. Three-Dimensional Elastomeric Scaffolds Designed with Cardiac-Mimetic Structural and Mechanical Features

    Science.gov (United States)

    Neal, Rebekah A.; Jean, Aurélie; Park, Hyoungshin; Wu, Patrick B.; Hsiao, James; Engelmayr, George C.; Langer, Robert

    2013-01-01

    Tissue-engineered constructs, at the interface of material science, biology, engineering, and medicine, have the capacity to improve outcomes for cardiac patients by providing living cells and degradable biomaterials that can regenerate the native myocardium. With an ultimate goal of both delivering cells and providing mechanical support to the healing heart, we designed three-dimensional (3D) elastomeric scaffolds with (1) stiffnesses and anisotropy mimicking explanted myocardial specimens as predicted by finite-element (FE) modeling, (2) systematically varied combinations of rectangular pore pattern, pore aspect ratio, and strut width, and (3) structural features approaching tissue scale. Based on predicted mechanical properties, three scaffold designs were selected from eight candidates for fabrication from poly(glycerol sebacate) by micromolding from silicon wafers. Large 20×20 mm scaffolds with high aspect ratio features (5:1 strut height:strut width) were reproducibly cast, cured, and demolded at a relatively high throughput. Empirically measured mechanical properties demonstrated that scaffolds were cardiac mimetic and validated FE model predictions. Two-layered scaffolds providing fully interconnected pore networks were fabricated by layer-by-layer assembly. C2C12 myoblasts cultured on one-layered scaffolds exhibited specific patterns of cell elongation and interconnectivity that appeared to be guided by the scaffold pore pattern. Neonatal rat heart cells cultured on two-layered scaffolds for 1 week were contractile, both spontaneously and in response to electrical stimulation, and expressed sarcomeric α-actinin, a cardiac biomarker. This work not only demonstrated several scaffold designs that promoted functional assembly of rat heart cells, but also provided the foundation for further computational and empirical investigations of 3D elastomeric scaffolds for cardiac tissue engineering. PMID:23190320

  11. Investigating the key factors in designing a communication skills program for medical students: A qualitative study

    OpenAIRE

    Mahdi Hazavehei, Seyyed M.; Moonaghi, Hossein Karimi; Moeini, Babak; Moghimbeigi, Abbas; Emadzadeh, Ali

    2015-01-01

    Introduction Medical students have a serious need to acquire communication skills with others. In many medical schools, special curriculums are developed to improve such skills. Effective training of communication skills requires expert curriculum design. The aim of this study was to explore the experiences and views of experts and stakeholders in order to design a suitable training program in communication skills for medical students. Methods The content analysis approach was used in this qu...

  12. Main circulator design features for HTR 100, HTR 500 and space heating plants

    International Nuclear Information System (INIS)

    Engel, J.; Glass, D.

    1988-01-01

    All design alternatives for modern high-temperature reactors have a common circulator concept: It is based on a vertical shaft design with a flying impeller. The circulators are equipped with active magnetic bearings and are driven by induction motors connected to variable-speed static converters. Due to their multiple functions during normal reactor operation and under accident conditions, extremely high requirements are made to safety-relevant circulators, since with the reactor pressurized as well as under depressurized conditions specified delivery heads and flow rates have to be ensured. The use of active magnetic bearings permits to obtain maintenance-free operation and functional safety to an extent which had not been achieved before. Magnetic bearings are therefore provided for the total range including primary gas circulators of a drive power of several MW as well as circulators for helium loops of reactor auxiliary systems. The essential feature for using active magnetic bearings is the retainer bearing technology, preventing contact between rotor and static circulator parts upon unintended deenergisation of the magnets. Results of current experiments are reported. Another aspect to be considered for reliable long-term operation for several decades is the effect of rotor dynamics. The various natural frequencies resulting from torsion and bending modes in view of a drive by a frequency-controlled induction motor have to be considered as well as the specific characteristics of the active magnetic bearings. Special attention has to be directed to the internal cooling loop so as to ensure that reactor temperature excursions in the event of deviation from normal operation can be overcome without damage. For circulator components exposed to temperature fields the design characteristics are determined by combining experimental and analytical methods. The coordination of all component parts is currently being optimized on a prototype circulator whose detailed

  13. Designing Biodiversity Friendly Communities. Liveable Cities Forum: Key outcomes and findings

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-10-15

    The Liveable Cities Forum, held 21-22 August in Montreal Canada, created a platform to share best practices on biodiversity management and application at the local level. The Forum also highlighted the importance of partnership building and presented instruments (such as the Singapore Index on Cities' Biodiversity) that help to move the biodiversity agenda forward. A findings report on the Forum has recently been released, offering panel and workshop summaries, key outcomes, and a scope of future opportunities for local governments. Some of the key outcomes are as follows: Biodiversity protection is at its core a local issue, and in order to mitigate biodiversity loss in cities, there is an undeniable need for local governments to come together and work through solutions collectively; Urban centers influence local, regional and global biodiversity. Therefore, it is important that cities con-serve their local biodiversity through the sustainable use of resources beyond their borders; It is important for municipalities to engage and partner with local residents, academic institutions, and organizations, not only to have a finger on the pulse, but also to have local allies and secure long-term support; and Integrated policies help drive action. To effectively mainstream biodiversity at the local level, it is important to incorporate biodiversity considerations into multiple departments, plans and programs.

  14. Key issues in the thermal design of spaceborne cryogenic infrared instruments

    Science.gov (United States)

    Schember, Helene R.; Rapp, Donald

    1992-12-01

    Thermal design and analysis play an integral role in the development of spaceborne cryogenic infrared (IR) instruments. From conceptual sketches to final testing, both direct and derived thermal requirements place significant constraints on the instrument design. Although in practice these thermal requirements are interdependent, the sources of most thermal constraints may be grouped into six distinct categories. These are: (1) Detector temperatures, (2) Optics temperatures, (3) Pointing or alignment stability, (4) Mission lifetime, (5) Orbit, and (6) Test and Integration. In this paper, we discuss these six sources of thermal requirements with particular regard to development of instrument packages for low background infrared astronomical observatories. In the end, the thermal performance of these instruments must meet a set of thermal requirements. The development of these requirements is typically an ongoing and interactive process, however, and the thermal design must maintain flexibility and robustness throughout the process. The thermal (or cryogenic) engineer must understand the constraints imposed by the science requirements, the specific hardware, the observing environment, the mission design, and the testing program. By balancing these often competing factors, the system-oriented thermal engineer can work together with the experiment team to produce an effective overall design of the instrument.

  15. Design features of offshore oil production platforms influence their susceptibility to biocorrosion.

    Science.gov (United States)

    Duncan, Kathleen E; Davidova, Irene A; Nunn, Heather S; Stamps, Blake W; Stevenson, Bradley S; Souquet, Pierre J; Suflita, Joseph M

    2017-08-01

    Offshore oil-producing platforms are designed for efficient and cost-effective separation of oil from water. However, design features and operating practices may create conditions that promote the proliferation and spread of biocorrosive microorganisms. The microbial communities and their potential for metal corrosion were characterized for three oil production platforms that varied in their oil-water separation processes, fluid recycling practices, and history of microbially influenced corrosion (MIC). Microbial diversity was evaluated by 16S rRNA gene sequencing, and numbers of total bacteria, archaea, and sulfate-reducing bacteria (SRB) were estimated by qPCR. The rates of 35 S sulfate reduction assay (SRA) were measured as a proxy for metal biocorrosion potential. A variety of microorganisms common to oil production facilities were found, but distinct communities were associated with the design of the platform and varied with different locations in the processing stream. Stagnant, lower temperature (production platforms can be used to identify operational practices that inadvertently promote the proliferation, distribution, and activity of biocorrosive microorganisms.

  16. Design and simulation of a new bidirectional actuator for haptic systems featuring MR fluid

    Science.gov (United States)

    Hung, Nguyen Quoc; Tri, Diep Bao; Cuong, Vo Van; Choi, Seung-Bok

    2017-04-01

    In this research, a new configuration of bidirectional actuator featuring MR fluid (BMRA) is proposed for haptic application. The proposed BMRA consists of a driving disc, a driving housing and a driven disc. The driving disc is placed inside the driving housing and rotates counter to each other by a servo DC motor and a bevel gear system. The driven shaft is also placed inside the housing and next to the driving disc. The gap between the two disc and the gap between the discs and the housing are filled with MR fluid. On the driven disc, two mutual magnetic coils are placed. By applying currents to the two coils mutually, the torque at the output shaft, which is fixed to the driven disc, can be controlled with positive, zero or negative value. This make the actuator be suitable for haptic application. After a review of MR fluid and its application, configuration of the proposed BMRA is presented. The modeling of the actuator is then derived based on Bingham rheological model of MRF and magnetic finite element analysis (FEA). The optimal design of the actuator is then performed to minimize the mass of the BMRA. From the optimal design result, performance characteristics of the actuator is simulated and detailed design of a prototype actuator is conducted.

  17. Optimal design of a new 3D haptic gripper for telemanipulation, featuring magnetorheological fluid brakes

    International Nuclear Information System (INIS)

    Nguyen, Q H; Choi, S B; Lee, Y S; Han, M S

    2013-01-01

    In this research work, a new configuration of a 3D haptic gripper for telemanipulation is proposed and optimally designed. The proposed haptic gripper, featuring three magnetorheological fluid brakes (MRBs), reflects the rolling torque, the grasping force and the approach force from the slave manipulator to the master operator. After describing the operational principle of the haptic gripper, an optimal design of the MRBs for the gripper is performed. The purpose of the optimization problem is to find the most compact MRB that can provide a required braking torque/force to the master operator while the off-state torque/force is kept as small as possible. In the optimal design, different types of MRBs and different MR fluids (MRFs) are considered. In order to obtain the optimal solution of the MRBs, an optimization approach based on finite element analysis (FEA) integrated with an optimization tool is used. The optimal solutions of the MRBs are then obtained and the optimized MRBs for the haptic gripper are identified. In addition, discussions on the optimal solutions and performance of the optimized MRBs are given. (paper)

  18. Specific features of designs of superconducting magnets for high-energy synchrotrons

    International Nuclear Information System (INIS)

    Monoszon, N.A.

    1979-01-01

    Distinctive features of designs of synchrotron superconducting magnetic systems (SMS) are considered. Some results of testing the prototypes of the ISABELLE storage ring magnets, the DABLER energy doubler and the accelerating-storage complex project are presented. Designs of di.ooles and quadrupoles are described. It is shown that the design of the DABLER SMS considerably differs from the ISABELLE SMS. The DABLER uses nonsaturated magnetic screens which provide lesser distortions of the magnetic field distribution. For the ISABELLE project a dipole with a two-layer winding has been developed which produced a field of 6.2 T. Magnetization curves as well as training and field distribution curves for a number of DABLER dipoles are presented. To prevent local overheating provision is made for using a heater enclosed in a winding. A 1 m dipole model with a sector winding of the DABLER type has been manufactured and tested in the IHEP. During tests a short-sample current and a total value of calculated field equal to 4.45 T in the chamber centre amd 5.3 T in the winding have been achieved

  19. Design basis and design features of WWER-440 model 213 nuclear power plants. Reference plant: Bohunice V2 (Slovakia)

    International Nuclear Information System (INIS)

    1994-05-01

    The prime objective of the IAEA Technical Co-operation Project on Evaluation of Safety Aspects of WWER-440 model 213 NPPs is to co-ordinate and to integrate assistance to national organizations in studying selected aspects of safety for the same type of reactors. Consequently, the study integrated the results generated by national activities carried out in the Czech Republic, Hungary, Slovakia and Ukraine and co-ordinated through the IAEA. Valuable assistance in carrying out the tasks was also provided by Bulgaria and Poland. A set of publications is being prepared to present the results of the project. The publications are intended to facilitate the review and utilization of the results of the project. They are also providing assistance in further refinement and/or extension of plant specific safety evaluation of model 213 NPPs. This Technical Document addressing the design basis and safety related design features of WWER-440 model 213 plants is the first of the series to be published. It is hoped that this document will be useful to anyone working in the field of WWER safety, and in particular to experts planning, executing or reviewing studies related to the subject. Refs, 36 figs, tabs

  20. Design data and safety features of commercial nuclear power plants. Vol. IV. Dockets 50-452 through 50-503

    International Nuclear Information System (INIS)

    Heddleson, F.A.

    1975-03-01

    Design data, safety features, and site characteristics are summarized for 36 nuclear power units in 18 power stations in the United States. Six pages of data are presented for each plant consisting of thermal-hydraulic and nuclear factors, containment features, emergency-core-cooling systems, site features, circulating water system data, and miscellaneous factors. An aerial perspective is also presented for each plant. The volume covers reactors with dockets 50-452 through 50-503. (U.S.)

  1. Flexible displays as key for high-value and unique automotive design

    Science.gov (United States)

    Isele, Robert

    2011-03-01

    Within the last few years' car industry changed very fast. Information and Communication became more important and displays are now standard in nearly every car. But this is not the only trend which could be recognized in this industry. CO2 emission, fuel price as well as the increasing traffic inside the Mega Cities initialized a big change in the behavior of the customers. The big battle for the car industry will enter the interior extremely fast, and the premium cars need ore innovative design icons. Flexible Displays are one big step that enables totally different designs and a new value of the driver experience.

  2. Design and implementation of a contactless multiple hand feature acquisition system

    Science.gov (United States)

    Zhao, Qiushi; Bu, Wei; Wu, Xiangqian; Zhang, David

    2012-06-01

    In this work, an integrated contactless multiple hand feature acquisition system is designed. The system can capture palmprint, palm vein, and palm dorsal vein images simultaneously. Moreover, the images are captured in a contactless manner, that is, users need not to touch any part of the device when capturing. Palmprint is imaged under visible illumination while palm vein and palm dorsal vein are imaged under near infrared (NIR) illumination. The capturing is controlled by computer and the whole process is less than 1 second, which is sufficient for online biometric systems. Based on this device, this paper also implements a contactless hand-based multimodal biometric system. Palmprint, palm vein, palm dorsal vein, finger vein, and hand geometry features are extracted from the captured images. After similarity measure, the matching scores are fused using weighted sum fusion rule. Experimental results show that although the verification accuracy of each uni-modality is not as high as that of state-of-the-art, the fusion result is superior to most of the existing hand-based biometric systems. This result indicates that the proposed device is competent in the application of contactless multimodal hand-based biometrics.

  3. Design features which mitigate severe accident challenges in the GE ABWR and SBWR

    International Nuclear Information System (INIS)

    Buchholz, Carol E.

    2004-01-01

    A reduction of the requirements for the emergency planning zone (EPZ) is a goal of advanced light water reactors. The technical basis for reducing the EPZ requirements is based on a very low frequency of a severe accident and high confidence that the offsite dose would be low even if a severe accident was to occur. Design features have been included in both the ABWR and SBWR to ensure that both of these goals are achieved. Probabilistic Risk Assessments (PRAs) have been performed for both plants. The PRAs indicate a core damage frequency on the order of IE-7 for both plants. The PRAs also show that the containments will not fail even if a severe accident should occur. The potential offsite is extremely low. (author)

  4. Digging deeper into platform game level design: session size and sequential features

    DEFF Research Database (Denmark)

    Shaker, Noor; Yannakakis, Georgios N.; Togelius, Julian

    2012-01-01

    A recent trend within computational intelligence and games research is to investigate how to affect video game players’ in-game experience by designing and/or modifying aspects of game content. Analysing the relationship between game content, player behaviour and self-reported affective states...... constitutes an important step towards understanding game experience and constructing effective game adaptation mechanisms. This papers reports on further refinement of a method to understand this relationship by analysing data collected from players, building models that predict player experience...... and analysing what features of game and player data predict player affect best. We analyse data from players playing 780 pairs of short game sessions of the platform game Super Mario Bros, investigate the impact of the session size and what part of the level that has the major affect on player experience...

  5. Spherical phantom for research of radiation situation in outer space. Design-structural special features

    International Nuclear Information System (INIS)

    Kartsev, I.S.; Eremenko, V.G.; Petrov, V.I.; Polenov, B.V.; Yudin, V.N.; Akatov, Yu.A.; Petrov, V.M.; Shurshakov, V.A.

    2005-01-01

    The design-structural features of the updated spherical phantom applied within the frameworks of the space experiment Matreshka-R at the Russian segment of International space station during ISS-8 and ISS-9 expeditions are described. The replacement of 48 polyethylene containers with TLD and STD assemblies by 16 cases installed from external side of the phantom and 4 tissue-equivalent caps of the central disk by 4 cases with detector assemblies is carried out. The updated tissue-equivalent phantom contains the active dosemeter based on 5 MOS detectors. The phantom cover is made from the non-flammable material NT-7. The basic characteristics of the flight specimen of the phantom are presented. The results of its on-Earth testing and real space flights are analyzed [ru

  6. Improvement of operation efficiency for WWER-440 and WWER-1000 for TRIGON fuel assembly design features

    Energy Technology Data Exchange (ETDEWEB)

    Silberstein, A [European WWER Fuels GmbH, Lyon (France)

    1994-12-31

    TRIGON 440 and TRIGON 1000 fuel assemblies and their assembly matching counterparts are described. Their role in increasing the efficiency of WWER reactors is stressed. Special attention is paid to their design features as well as calibrated means of predicting behaviour under irradiation from light water reactor core operation. They reduce the fuel cycle cost as a result of the reduced need for natural uranium which have to be enriched and of the smaller number of fuel assemblies which have to be fabricated, stored or reprocessed. The improved control assemblies bring comfort to the plant operator due to intrinsic progress in safety with respect to accidental situation, trouble-free behaviour and long time utilization in the reactor. 14 figs.

  7. Key Feature of the Catalytic Cycle of TNF-α Converting Enzyme Involves Communication Between Distal Protein Sites and the Enzyme Catalytic Core

    International Nuclear Information System (INIS)

    Solomon, A.; Akabayov, B.; Frenkel, A.; Millas, M.; Sagi, I.

    2007-01-01

    Despite their key roles in many normal and pathological processes, the molecular details by which zinc-dependent proteases hydrolyze their physiological substrates remain elusive. Advanced theoretical analyses have suggested reaction models for which there is limited and controversial experimental evidence. Here we report the structure, chemistry and lifetime of transient metal-protein reaction intermediates evolving during the substrate turnover reaction of a metalloproteinase, the tumor necrosis factor-α converting enzyme (TACE). TACE controls multiple signal transduction pathways through the proteolytic release of the extracellular domain of a host of membrane-bound factors and receptors. Using stopped-flow x-ray spectroscopy methods together with transient kinetic analyses, we demonstrate that TACE's catalytic zinc ion undergoes dynamic charge transitions before substrate binding to the metal ion. This indicates previously undescribed communication pathways taking place between distal protein sites and the enzyme catalytic core. The observed charge transitions are synchronized with distinct phases in the reaction kinetics and changes in metal coordination chemistry mediated by the binding of the peptide substrate to the catalytic metal ion and product release. Here we report key local charge transitions critical for proteolysis as well as long sought evidence for the proposed reaction model of peptide hydrolysis. This study provides a general approach for gaining critical insights into the molecular basis of substrate recognition and turnover by zinc metalloproteinases that may be used for drug design

  8. Insight, innovation, and the big picture in system design : application of FunKey architecting

    NARCIS (Netherlands)

    Bonnema, Gerrit Maarten

    2010-01-01

    Systems architecting is the design phase where the top-level functions and performance of a system are distributed over the system's parts, its environment, and its users. Up till now, system architects had to largely learn the required skills in practice. Some courses exist that teach the right

  9. Simulation as a key to success in power supply design and development

    Energy Technology Data Exchange (ETDEWEB)

    Suur-Askola, S.; Laasonen, M.; Maeki, J. [Efore Muuntolaite Oy, Vantaa (Finland)

    1997-12-31

    This paper describes the design and development process of a power supply by using simulation methods. The simulation principles and results of a 40W power supply are provided including EMI, voltage and current rating verification as well as power loss approximation. (orig.) 8 refs.

  10. Conceptual design activities and key issues on LHD-type reactor FFHR

    International Nuclear Information System (INIS)

    Sagara, A.; Mitarai, O.; Imagawa, S.; Morisaki, T.; Tanaka, T.; Mizuguchi, N.; Dolan, T.; Miyazawa, J.; Takahata, K.; Chikaraishi, H.; Yamada, S.; Seo, K.; Sakamoto, R.; Masuzaki, S.; Muroga, T.; Yamada, H.; Fukada, S.; Hashizume, H.; Yamazaki, K.; Mito, T.; Kaneko, O.; Mutoh, T.; Ohyabu, N.; Noda, N.; Komori, A.; Sudo, S.; Motojima, O.

    2006-01-01

    An overview of conceptual design activities on the LHD-type helical reactor FFHR is presented, mainly focusing on optimization studies on the reactor size and the proposal of a long-life blanket. A major radius of around 15 m is the present candidate under the constraints of the energy confinement achieved in LHD, a maximum magnetic field around 13 T with a current density around 30 A/mm 2 and a neutron wall loading around 1.5 MW/m 2 . R and D on super-conducting magnet systems of large scale, high field and high current-density are new challenging targets based on the LHD. The development of new design tools has been started aiming at establishing a virtual power plant (VPP) and a virtual reality system for 3D design assisting. Next design issues are mainly on engineering optimization of the first wall thickness, the detailed 3D blanket system, and unscheduled replacements of breeder blankets

  11. A key and a hero : An essay on the current state of urban design

    NARCIS (Netherlands)

    Calabrese, L.M.

    2011-01-01

    This issue of Atlantis highlights the ‘old question’ of urban form and the role of Urban Design within it. This is not without reason. In the past decades remarkably negative opinions were voiced on the urban condition and particularly on public space. In the 1990s Michael Sorkin’s well known

  12. Comparison of patellofemoral outcomes after TKA using two prostheses with different patellofemoral design features.

    Science.gov (United States)

    Bae, Dae Kyung; Baek, Jong Hun; Yoon, Kyung Tack; Son, Hyuck Sung; Song, Sang Jun

    2017-12-01

    The purpose of the present study was to compare the clinical and radiographic results after TKA using two prostheses with different sagittal patellofemoral design features, including outcomes related to compatibility of the patellofemoral joint. The clinical and radiographic results of 81 patients (100 knees) who underwent TKA using the specific prosthesis (group A) were compared with those in a control group who underwent TKA using the other prosthesis (group B). The presence of anterior knee joint pain, patellar crepitation, and patellar clunk syndrome was also checked. The function score and maximum flexion angle at the last follow-up were slightly better in group A than those in group B (92.0 ± 2.3 vs. 90.6 ± 4.2) (133.6° ± 8.4° vs. 129.6° ± 11.4°). Anterior knee pain was observed in 6 knees and patellar crepitation in four knees in group A. In group B, these symptoms were observed in 22 knees and 18 knees, respectively. There was no patellar clunk syndrome in either group. The alignment was corrected with satisfactory positioning of components. The patellar height remained unchanged after TKA in the two groups. The differences between preoperative and postoperative patellar tilt angle and patellar translation were small. When comparing the clinical and radiographic results after TKA using two prostheses with different sagittal patellofemoral design features, TKA using the specific prosthesis provided satisfactory results with less clinical symptoms related to the patellofemoral kinematics with TKA using the other prosthesis. III.

  13. SOME FEATURES OF THE DESIGN AND CONSTRUCTION OF UNDERGROUND PUBLIC AND SHOPPING CENTRE WITH PARKING IN MINSK

    Directory of Open Access Journals (Sweden)

    V. H. Pastushkov

    2010-03-01

    Full Text Available In the article some features of designing and construction, experimental-and-theoretical researches of structures of the multifunctional underground complex (public shopping center with parking on theIndependencesq. in Minsk are considered.

  14. Accessing microfluidics through feature-based design software for 3D printing

    Science.gov (United States)

    Shankles, Peter G.; Millet, Larry J.; Aufrecht, Jayde A.

    2018-01-01

    Additive manufacturing has been a cornerstone of the product development pipeline for decades, playing an essential role in the creation of both functional and cosmetic prototypes. In recent years, the prospects for distributed and open source manufacturing have grown tremendously. This growth has been enabled by an expanding library of printable materials, low-cost printers, and communities dedicated to platform development. The microfluidics community has embraced this opportunity to integrate 3D printing into the suite of manufacturing strategies used to create novel fluidic architectures. The rapid turnaround time and low cost to implement these strategies in the lab makes 3D printing an attractive alternative to conventional micro- and nanofabrication techniques. In this work, the production of multiple microfluidic architectures using a hybrid 3D printing-soft lithography approach is demonstrated and shown to enable rapid device fabrication with channel dimensions that take advantage of laminar flow characteristics. The fabrication process outlined here is underpinned by the implementation of custom design software with an integrated slicer program that replaces less intuitive computer aided design and slicer software tools. Devices are designed in the program by assembling parameterized microfluidic building blocks. The fabrication process and flow control within 3D printed devices were demonstrated with a gradient generator and two droplet generator designs. Precise control over the printing process allowed 3D microfluidics to be printed in a single step by extruding bridge structures to ‘jump-over’ channels in the same plane. This strategy was shown to integrate with conventional nanofabrication strategies to simplify the operation of a platform that incorporates both nanoscale features and 3D printed microfluidics. PMID:29596418

  15. Accessing microfluidics through feature-based design software for 3D printing.

    Science.gov (United States)

    Shankles, Peter G; Millet, Larry J; Aufrecht, Jayde A; Retterer, Scott T

    2018-01-01

    Additive manufacturing has been a cornerstone of the product development pipeline for decades, playing an essential role in the creation of both functional and cosmetic prototypes. In recent years, the prospects for distributed and open source manufacturing have grown tremendously. This growth has been enabled by an expanding library of printable materials, low-cost printers, and communities dedicated to platform development. The microfluidics community has embraced this opportunity to integrate 3D printing into the suite of manufacturing strategies used to create novel fluidic architectures. The rapid turnaround time and low cost to implement these strategies in the lab makes 3D printing an attractive alternative to conventional micro- and nanofabrication techniques. In this work, the production of multiple microfluidic architectures using a hybrid 3D printing-soft lithography approach is demonstrated and shown to enable rapid device fabrication with channel dimensions that take advantage of laminar flow characteristics. The fabrication process outlined here is underpinned by the implementation of custom design software with an integrated slicer program that replaces less intuitive computer aided design and slicer software tools. Devices are designed in the program by assembling parameterized microfluidic building blocks. The fabrication process and flow control within 3D printed devices were demonstrated with a gradient generator and two droplet generator designs. Precise control over the printing process allowed 3D microfluidics to be printed in a single step by extruding bridge structures to 'jump-over' channels in the same plane. This strategy was shown to integrate with conventional nanofabrication strategies to simplify the operation of a platform that incorporates both nanoscale features and 3D printed microfluidics.

  16. Sensitivity Analysis of Wind Plant Performance to Key Turbine Design Parameters: A Systems Engineering Approach; Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Dykes, K.; Ning, A.; King, R.; Graf, P.; Scott, G.; Veers, P.

    2014-02-01

    This paper introduces the development of a new software framework for research, design, and development of wind energy systems which is meant to 1) represent a full wind plant including all physical and nonphysical assets and associated costs up to the point of grid interconnection, 2) allow use of interchangeable models of varying fidelity for different aspects of the system, and 3) support system level multidisciplinary analyses and optimizations. This paper describes the design of the overall software capability and applies it to a global sensitivity analysis of wind turbine and plant performance and cost. The analysis was performed using three different model configurations involving different levels of fidelity, which illustrate how increasing fidelity can preserve important system interactions that build up to overall system performance and cost. Analyses were performed for a reference wind plant based on the National Renewable Energy Laboratory's 5-MW reference turbine at a mid-Atlantic offshore location within the United States.

  17. Investigating the key factors in designing a communication skills program for medical students: A qualitative study

    Science.gov (United States)

    Mahdi Hazavehei, Seyyed M.; Moonaghi, Hossein Karimi; Moeini, Babak; Moghimbeigi, Abbas; Emadzadeh, Ali

    2015-01-01

    Introduction Medical students have a serious need to acquire communication skills with others. In many medical schools, special curriculums are developed to improve such skills. Effective training of communication skills requires expert curriculum design. The aim of this study was to explore the experiences and views of experts and stakeholders in order to design a suitable training program in communication skills for medical students. Methods The content analysis approach was used in this qualitative study. Forty-three participants were selected from the faculty, nurses, physicians, residents, and medical students at Mashhad University of Medical Sciences using purposive sampling. The data were collected through focus group discussions and semi-structured interviews. To ensure the accuracy of the data, the criteria of credibility, transferability, dependability, and conformability were met. The data were analyzed by MAXQDA software using the Graneheim & Lundman model. Results The findings of this study consisted of two main themes, i.e., “The vast nature of the present communication skills training” and “administrative requirements of the training program regarding communication skills.” The first theme included the educational needs of students, the problems associated with training people to have good communication skills, the importance of good communication skills in performing professional duties, communication skills and job requirements, the learning environment of communication skills, and the status of existing training programs for communication skills. Strategies and suitable methods for teaching communication skills and methods of evaluating the students in this regard also were obtained. Conclusion The findings of this study were the elements required to design a proper and local model to teach communication skills to medical students through analyzing the concepts of effective communication. The results of this study can be useful for medical

  18. Investigating the key factors in designing a communication skills program for medical students: A qualitative study.

    Science.gov (United States)

    Mahdi Hazavehei, Seyyed M; Karimi Moonaghi, Hossein; Moeini, Babak; Moghimbeigi, Abbas; Emadzadeh, Ali

    2015-11-01

    Medical students have a serious need to acquire communication skills with others. In many medical schools, special curriculums are developed to improve such skills. Effective training of communication skills requires expert curriculum design. The aim of this study was to explore the experiences and views of experts and stakeholders in order to design a suitable training program in communication skills for medical students. The content analysis approach was used in this qualitative study. Forty-three participants were selected from the faculty, nurses, physicians, residents, and medical students at Mashhad University of Medical Sciences using purposive sampling. The data were collected through focus group discussions and semi-structured interviews. To ensure the accuracy of the data, the criteria of credibility, transferability, dependability, and conformability were met. The data were analyzed by MAXQDA software using the Graneheim & Lundman model. The findings of this study consisted of two main themes, i.e., "The vast nature of the present communication skills training" and "administrative requirements of the training program regarding communication skills." The first theme included the educational needs of students, the problems associated with training people to have good communication skills, the importance of good communication skills in performing professional duties, communication skills and job requirements, the learning environment of communication skills, and the status of existing training programs for communication skills. Strategies and suitable methods for teaching communication skills and methods of evaluating the students in this regard also were obtained. The findings of this study were the elements required to design a proper and local model to teach communication skills to medical students through analyzing the concepts of effective communication. The results of this study can be useful for medical faculties in designing a proper program for

  19. Investigation of process parameters influence on flash formation in injection moulding of polymer micro features through design of experiments

    DEFF Research Database (Denmark)

    Eladl, Abdelkhalik; Tosello, Guido; Mostafa, Rania

    Micro injection moulding is one of the key technologies for micro manufacture due to its mass-production capability and relatively low component cost. Flash defects are among the most critical issues in the replication of micro features and constitute a manufacturing constrain in applying injecti...

  20. On-off keying transmitter design for navigation by visible light communication

    Science.gov (United States)

    Louro, P.; Vieira, M.; Costa, J.; Vieira, M. A.

    2018-02-01

    White LEDS revolutionized the field of illumination technology mainly due to the energy saving effects. Besides lighting purposes LEDs can also be used in wireless communication systems when integrated in Visible Light Communication (VLC) systems. Indoor positioning for navigation in large buildings is currently under research to overcome the difficulties associated with the use of GPS in such environments. The motivation for this application is also supported by the possibility of taking advantage of an existing lighting and WiFi infrastructure. In this work it is proposed an indoor navigation system based on the use of VLC technology. The proposed system includes trichromatic white LEDs with the red and blue chips modulated at different frequencies and a pinpin photodetector with selective spectral sensitivity. Optoelectronic features of both optical sources and photodetector device are analyzed. The photodetector device consists two pin structures based on a-SiC:H and a-Si:H with geometrical configuration optimized for the detection of short and large wavelengths in the visible range. Its sensitivity is externally tuned by steady state optical bias. The localization algorithm makes use of the Fourier transform to identify the frequencies present in the photocurrent signal and the wavelength filtering properties of the sensor under front and back optical bias to detect the existing red and blue signals. The viability of the system was demonstrated through the implementation of an automatic algorithm to infer the photodetector cardinal direction. A capacitive optoelectronic model supports the experimental results and explains the device operation.

  1. Design of IP Camera Access Control Protocol by Utilizing Hierarchical Group Key

    Directory of Open Access Journals (Sweden)

    Jungho Kang

    2015-08-01

    Full Text Available Unlike CCTV, security video surveillance devices, which we have generally known about, IP cameras which are connected to a network either with or without wire, provide monitoring services through a built-in web-server. Due to the fact that IP cameras can use a network such as the Internet, multiple IP cameras can be installed at a long distance and each IP camera can utilize the function of a web server individually. Even though IP cameras have this kind of advantage, it has difficulties in access control management and weakness in user certification, too. Particularly, because the market of IP cameras did not begin to be realized a long while ago, systems which are systematized from the perspective of security have not been built up yet. Additionally, it contains severe weaknesses in terms of access authority to the IP camera web server, certification of users, and certification of IP cameras which are newly installed within a network, etc. This research grouped IP cameras hierarchically to manage them systematically, and provided access control and data confidentiality between groups by utilizing group keys. In addition, IP cameras and users are certified by using PKI-based certification, and weak points of security such as confidentiality and integrity, etc., are improved by encrypting passwords. Thus, this research presents specific protocols of the entire process and proved through experiments that this method can be actually applied.

  2. Design and construction features of steam generators at a nuclear power station

    International Nuclear Information System (INIS)

    Chakrabarti, A.K.; Gupta, K.N.; Bapat, C.N.; Sharma, V.K.

    1996-01-01

    The Indian nuclear power programme is based on Pressurised Heavy Water Reactors (PHWRs) using natural uranium as fuel and heavy water as reactor coolant as well as moderator. The nuclear heat is generated in the fuel located in the pressure tubes. Pressurised heavy water in the primary heat transport (PHT) system is circulated through the tubes which picks up the heat from the fuel and transfers it to ordinary water in steam generators (SGs) to produce steam. The steam is used for providing power to the turbine. The steam generator is a critical equipment in the nuclear steam supply system (NSSS) of a nuclear reactor. SG tube surface area constitute about 80% of total primary circuit surface area. A typical value in a 220 MWe reactor is 9000 m 2 which can release considerable amount of corrosion products unless very low corrosion rates are achieved by proper design, material selection and water chemistry control. Design and construction features of SGs are given. 1 tab

  3. Features of a time domain simulation tool for rigid riser design

    Energy Technology Data Exchange (ETDEWEB)

    Morooka, Celso K.; Brandt, Dustin M. [Universidade Estadual de Campinas (UNICAMP), SP (Brazil). Faculdade de Engenharia Mecanica. Dept. de Engenharia de Petroleo; Matt, Cyntia G.C.; Franciss, Ricardo [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil). Centro de Pesquisas

    2008-07-01

    This paper present a number of numerical implementations designed for the analysis of rigid riser's static and dynamic behavior that includes the effects of vortex induced vibrations (VIV) and marine hydrodynamic loads in time domain. Features include the ability to consider pipe with a free-span utilizing a soil/riser interaction model. An implementation of a numerical coupling scheme to couple the vertical riser and platform dynamics was developed to allow prediction of the sub sea Blow-Out Preventer (BOP) re-entry into a sub sea petroleum well when drilling different phases of deep and ultra-deep wells. The developments contains support for the consideration of the Self Standing Hybrid Riser (SSHR) configuration which has been shown to be a promising riser configuration in deep and ultra-deep waters. A graphical interface was also created to better grasp the results and aid in the modeling, processing and to help analyze the numerical simulations, contributing to enhance agility and quality of the riser design and analysis processes. (author)

  4. Power/Energy Estimator for Designing WSN Nodes with Ambient Energy Harvesting Feature

    Directory of Open Access Journals (Sweden)

    Jutel Dominique

    2011-01-01

    Full Text Available Abstract Wireless Sensor Networks (WSNs consist of spatially distributed autonomous sensors to cooperatively monitor physical conditions. Thus, the node battery autonomy is critical. To outperform it, most WSNs rely on the harvesting capability. As nodes can recharge whenever energy is available, the problem is to determine at design time the node autonomy. For our project, we solve it by creating a power/energy estimator that simulates business scenarios to predict node autonomy; the estimation concerns both power and energy features. Based on node architecture configuration, its Dynamic Power Management (DPM policy, and environmental conditions, we present a simulator that helps identify power consumption hot spots and make critical choices during the system design. It also helps to scale the energy storage system as well as the energy harvesters correctly. The hardware part is modelled using the FLPA methodology to develop different node component models with a variable accuracy. For the logical part, we developped a specific DPM by integrating meteorology and weather forecast behaviours. The novelty comes from the ability to simulate the WSN harvesting capability and to estimate at runtime the remaining duration of each service.

  5. Design and control of a hybrid mount featuring a magnetorheological fluid and a piezostack

    International Nuclear Information System (INIS)

    Han, Young-Min; Choi, Sang-Min; Choi, Seung-Bok; Lee, Ho-Guen

    2011-01-01

    In this study, a hybrid mount featuring a magnetorheological (MR) fluid and a piezostack is devised to reduce vibrations occuring in dynamic systems which are operated in a wide frequency range. An MR fluid is adopted to improve isolation performance at resonant low frequencies, whereas a piezostack actuator is adopted for performance improvement at non-resonant high frequencies. As a first step, a passive rubber part is manufactured and its dynamic characteristics are experimentally evaluated. By adopting the MR fluid and the piezostack, semi-active and active actuating mechanisms are devised and their mathematical models are derived. In particular, the magnetic circuit for MR operation is optimally designed via finite element analysis. After evaluating the dynamic characteristics of the manufactured MR device and inertial piezostack actuator, the proposed hybrid mount is then established by integrating them with the rubber part. Subsequently, a vibration control system is constructed using the proposed hybrid mount, and a sliding mode controller (SMC) is designed to attenuate the vibrations transmitted from the base excitation. Control performances of the proposed mount are experimentally evaluated in time and frequency domains

  6. Cigarette Design Features in Low-, Middle-, and High-Income Countries

    Directory of Open Access Journals (Sweden)

    Rosalie V. Caruso

    2012-01-01

    Full Text Available Previous studies have shown that country income grouping is correlated with cigarette engineering. Cigarettes (=111 brands were purchased during 2008–2010 from 11 low-, middle-, and high-income countries to assess physical dimensions and an array of cigarette design features. Mean ventilation varied significantly across low- (7.5%, middle- (15.3%, and high-income (26.2% countries (≤0.001. Differences across income groups were also seen in cigarette length (=0.001, length of the tipping paper (=0.01, filter weight (=0.017, number of vent rows (=0.003, per-cigarette tobacco weight (=0.04, and paper porosity (=0.008. Stepwise linear regression showed ventilation and tobacco length as major predictors of ISO tar yields in low-income countries (=0.909, 0.047, while tipping paper (<0.001, filter length (<0.001, number of vent rows (=0.014, and per-cigarette weight (=0.015 were predictors of tar yields in middle-income countries. Ventilation (<0.001, number of vent rows (=0.009, per-cigarette weight (<0.001, and filter diameter (=0.004 predicted tar yields in high-income countries. Health officials must be cognizant of cigarette design issues to provide effective regulation of tobacco products.

  7. Design features of the Light Water Breeder Reactor (LWBR) which improve fuel utilization in light water reactors (LWBR development program)

    International Nuclear Information System (INIS)

    Hecker, H.C.; Freeman, L.B.

    1981-08-01

    This report surveys reactor core design features of the Light Water Breeder Reactor which make possible improved fuel utilization in light water reactor systems and breeding with the uranium-thorium fuel cycle. The impact of developing the uranium-thorium fuel cycle on utilization of nuclear fuel resources is discussed. The specific core design features related to improved fuel utilization and breeding which have been implemented in the Shippingport LWBR core are presented. These design features include a seed-blanket module with movable fuel for reactivity control, radial and axial reflcetor regions, low hafnium Zircaloy for fuel element cladding and structurals, and a closely spaced fuel rod lattice. Also included is a discussion of several design modifications which could further improve fuel utilization in future light water reactor systems. These include further development of movable fuel control, use of Zircaloy fuel rod support grids, and fuel element design modifications

  8. Flexibility and adaptability - key elements of end-user participation in living space designing

    Directory of Open Access Journals (Sweden)

    Jakšić Željko

    2017-01-01

    Full Text Available An end-user has the main role in the creation of space where spends most of its lifetime (home, workplace. That is why important that a designer (he first recognizes what requests of the end-user are. In the reference literature and researches that deal with the spatial organisations and designing of living area, the role of an end-user is essential. However, what does the end user participation mean, actually? At what level an end-user makes a final decision? Is it a choice among several alternative solutions provided by an architect or end-user himself? This article precisely deals with that subject - where begins and where ends participation of the end-user when the theme is the final spatial solution and under what circumstances. In this case, habitation represents the much more sensitive area than any other area for human needs or activities. In technical terms, an end-user could be someone who either knows nothing or knows a lot but not enough about both the spatial and functional organisations. His role should be reduced to choice of one from the group of high-quality solutions and, in a technical sense, logical solutions made by an expert. No more than that.

  9. Designing ecological climate change impact assessments to reflect key climatic drivers.

    Science.gov (United States)

    Sofaer, Helen R; Barsugli, Joseph J; Jarnevich, Catherine S; Abatzoglou, John T; Talbert, Marian K; Miller, Brian W; Morisette, Jeffrey T

    2017-07-01

    Identifying the climatic drivers of an ecological system is a key step in assessing its vulnerability to climate change. The climatic dimensions to which a species or system is most sensitive - such as means or extremes - can guide methodological decisions for projections of ecological impacts and vulnerabilities. However, scientific workflows for combining climate projections with ecological models have received little explicit attention. We review Global Climate Model (GCM) performance along different dimensions of change and compare frameworks for integrating GCM output into ecological models. In systems sensitive to climatological means, it is straightforward to base ecological impact assessments on mean projected changes from several GCMs. Ecological systems sensitive to climatic extremes may benefit from what we term the 'model space' approach: a comparison of ecological projections based on simulated climate from historical and future time periods. This approach leverages the experimental framework used in climate modeling, in which historical climate simulations serve as controls for future projections. Moreover, it can capture projected changes in the intensity and frequency of climatic extremes, rather than assuming that future means will determine future extremes. Given the recent emphasis on the ecological impacts of climatic extremes, the strategies we describe will be applicable across species and systems. We also highlight practical considerations for the selection of climate models and data products, emphasizing that the spatial resolution of the climate change signal is generally coarser than the grid cell size of downscaled climate model output. Our review illustrates how an understanding of how climate model outputs are derived and downscaled can improve the selection and application of climatic data used in ecological modeling. © 2017 John Wiley & Sons Ltd.

  10. Design Feature and Prototype Testing Methodology of DHIC's Nuclear I and C System

    International Nuclear Information System (INIS)

    Kim, K.H.; Baeg, S.Y.; Kim, S.A.; Lee, S.J.; Yoon, S.P.; Park, C.Y.

    2011-01-01

    The DHIC has developed an I and C system for a nuclear power plant through a Korean Government R and D project since 2001. This I and C system was designed and implemented to be applied for the new 1400MW nuclear power plant of KHNP. This system's design is based on the class-1E PLC platform and the non-class1E DCS platform. The PPS, the ESF-CCS, the RCOPS, the QIAS-P/N, the PCS, the NPCS, the P-CCS and the NIMS were designed, implemented and tested. The R and D project has been developed under a systematic and guided QA plan, but it is not easy to be applied for a new NPP such as Shin-Ulchin 1 and 2. To resolve problems of the first-application concerns, a new idea of integrated performance testing was adopted. A main control room for a verification test facility was constructed and it has features of a compact, video-based man-machine interface. The MCR includes five operation consoles, a Large Display Panel. A test system for a verification test facility is implemented as similar as a control and protection system of SUN 1 and 2. Integration level tests such as a system test, an interface test, a MMI test, a system function/performance test, a failure mode test, a response time test, a network load test, an alarm test, a reactor power cutback system test, an unit load transient test and a scenario test were performed using the prototype test facilities. These kinds of testing can verify and pre-validate the integrated I and C system's performance and flexibility. It could offer an implementation training before construction and also minimize trial errors to be found in the site. (author)

  11. Comparison of design features and mechanical properties of commercially available Veress needles.

    Science.gov (United States)

    Schramel, Johannes P; Kindslehner, Angelika; Bockstahler, Barbara A; Dupré, Gilles P

    2017-10-01

    To compare design features and mechanical properties of 13 commercially available Veress needles (VN). In vitro biomechanical study. Veress needles from 9 manufacturers (6 reusable, 6 disposable, and 1 with a reusable stylet combined with a disposable cannula) were included in the study. Veress needles are designed with a spring-loaded stylet to protect the tip of the cannula following insertion into the abdomen. Stylet forces were measured with a scale in a test jig by moving the stylet in 0.5 mm steps into the hollow cannula. Forces and spring rates were derived from force-displacement plots. Mass, mechanical dimensions, and the bevel angle and geometry were assessed. Differences between VN models were analyzed with a univariate analysis of variance. Results are reported as mean ± SD or median (range). Physical and mechanical parameters differed between models. The exposed stylet length was 3.5 mm (2-7). Three bevel geometries (bias, lancet type, and back-cut) with angles between 20° and 40° were identified. Reusable VN weigh more (24.9 ± 2.2 g) than disposable designs (6.0 ± 2.3 g). The mean values for the spring rate and the residual stylet force were 0.23 ± 0.08 Nmm -1 and 0.94 ± 0.28 N, respectively. The mean force required to move the stylet to the cannula tip was 1.81 ± 0.29 N and 2.77 ± 0.54 N to move to the proximal end of the bevel. Commercially available VN use diverse bevel geometries and have different mechanical characteristics. Studies investigating laparoscopic entry complications should explicitly report the type of VN model used. © 2017 The American College of Veterinary Surgeons.

  12. Steam generator thermal hydraulic design & functional architecture features and related operational and reliability issues requiring consideration

    International Nuclear Information System (INIS)

    Klarner, R.G.

    2012-01-01

    Proper thermal hydraulic design and functional architecture are critical to successful steam generator operation and long term reliability. The evolution of steam generators has been a gradual learning process that has benefited from continuous industry operational experience (OPEX). Inadequate thermal hydraulic design can lead to numerous degradation mechanisms such as excessive deposition, corrosion, flow and level instabilities, fluid-elastic instabilities and tube wear. The functional architecture determines the health of the tube bundle and the other internals during manufacturing, handling and operation. It also determines thermal performance as well as establishing global thermal-hydraulic characteristics such as water level shrink and swell response. This paper discusses the range of operational and reliability issues and relates them to the thermal hydraulic attributes and functional architecture of steam generators (many SG reliability issues are further discussed in other presentations at this conference). In pursuing such issues, the paper focuses on the four major features of the equipment, identifying in each case the goals and requirements such features must meet. Typical approaches and the means by which such requirements are addressed in current equipment are discussed. The four features are: 1. Tubing Material and Tube Bundle Heat Transfer Performance; a. Two materials are in current use – Alloy 690 TT and Alloy 800. Both are good materials with excellent performance records which serve their owners very well (the reliability attributes of Alloy 800 and 690 are discussed in other papers at this conference). Caution is advised in the supply of any material: – material quality is only assured by what is specified to material suppliers in procurement specifications – i.e. - all the knowledge and research in the world assures nothing if its findings are not reflected in procurement requirements. b. Heat transfer performance in addition to being

  13. The cognitive impact of interactive design features for learning complex materials in medical education.

    Science.gov (United States)

    Song, Hyuksoon S; Pusic, Martin; Nick, Michael W; Sarpel, Umut; Plass, Jan L; Kalet, Adina L

    2014-02-01

    To identify the most effective way for medical students to interact with a browser-based learning module on the symptoms and neurological underpinnings of stroke syndromes, this study manipulated the way in which subjects interacted with a graphical model of the brain and examined the impact of functional changes on learning outcomes. It was hypothesized that behavioral interactions that were behaviorally more engaging and which required deeper consideration of the model would result in heightened cognitive interaction and better learning than those whose manipulation required less deliberate behavioral and cognitive processing. One hundred forty four students were randomly assigned to four conditions whose model controls incorporated features that required different levels of behavioral and cognitive interaction: Movie (low behavioral/low cognitive, n = 40), Slider (high behavioral/low cognitive, n = 36), Click (low behavioral/high cognitive, n = 30), and Drag (high behavioral/high cognitive, n = 38). Analysis of Covariates (ANCOVA) showed that students who received the treatments associated with lower cognitive interactivity (Movie and Slider) performed better on a transfer task than those receiving the module associated with high cognitive interactivity (Click and Drag, partial eta squared = .03). In addition, the students in the high cognitive interactivity conditions spent significantly more time on the stroke locator activity than other conditions (partial eta squared = .36). The results suggest that interaction with controls that were tightly coupled with the model and whose manipulation required deliberate consideration of the model's features may have overtaxed subjects' cognitive resources. Cognitive effort that facilitated manipulation of content, though directed at the model, may have resulted in extraneous cognitive load, impeding subjects in recognizing the deeper, global relationships in the materials. Instructional designers must, therefore, keep in

  14. Designkey element of creative industries in Romania and its role in Romanian export

    Directory of Open Access Journals (Sweden)

    Costin LIANU

    2012-06-01

    Full Text Available Creative industries are now considered a solution for sustainable development. EU 2020 strategy is considering these industries crucial for the future industrial policy of EU. In recent years, while some European countries or even  regions and cities, such as the UK, Scandinavian countries cities like  Barcelona, Tallinn, Copenhagen or Amsterdam to name a few, have been good at tapping into the extraordinary potential of the cultural and creative sectors as a way to promote socioeconomic development and progressively developed ad hoc strategies, others are only just starting. Present papers is aiming at evaluating potential of these industries in Romania, with focus on design, and their possible place in the future export development of the country. Where strategies have emerged, they tend to focus on the strengthening of these sectors and not yet on stimulating partnerships and spill-overs with other sectors.

  15. Advancement of Systems Designs and Key Engineering Technologies for Materials Based Hydrogen Storage

    Energy Technology Data Exchange (ETDEWEB)

    van Hassel, Bart A. [United Technologies Research Center, East Hartford, CT (United States)

    2015-09-18

    UTRC lead the development of the Simulink Framework model that enables a comparison of different hydrogen storage systems on a common basis. The Simulink Framework model was disseminated on the www.HSECoE.org website that is hosted by NREL. UTRC contributed to a better understanding of the safety aspects of the proposed hydrogen storage systems. UTRC also participated in the Failure Mode and Effect Analysis of both the chemical- and the adsorbent-based hydrogen storage system during Phase 2 of the Hydrogen Storage Engineering Center of Excellence. UTRC designed a hydrogen storage system with a reversible metal hydride material in a compacted form for light-duty vehicles with a 5.6 kg H2 storage capacity, giving it a 300 miles range. It contains a heat exchanger that enables efficient cooling of the metal hydride material during hydrogen absorption in order to meet the 3.3 minute refueling time target. It has been shown through computation that the kinetics of hydrogen absorption of Ti-catalyzed NaAlH4 was ultimately limiting the rate of hydrogen absorption to 85% of the material capacity in 3.3 minutes. An inverse analysis was performed in order to determine the material property requirements in order for a metal hydride based hydrogen storage system to meet the DOE targets. Work on metal hydride storage systems was halted after the Phase 1 to Phase 2 review due to the lack of metal hydride materials with the required material properties. UTRC contributed to the design of a chemical hydrogen storage system by developing an adsorbent for removing the impurity ammonia from the hydrogen gas, by developing a system to meter the transport of Ammonia Borane (AB) powder to a thermolysis reactor, and by developing a gas-liquid-separator (GLS) for the separation of hydrogen gas from AB slurry in silicone oil. Stripping impurities from hydrogen gas is essential for a long life of the fuel cell system on board of a vehicle. Work on solid transport of AB was halted after the

  16. Security of Color Image Data Designed by Public-Key Cryptosystem Associated with 2D-DWT

    Science.gov (United States)

    Mishra, D. C.; Sharma, R. K.; Kumar, Manish; Kumar, Kuldeep

    2014-08-01

    In present times the security of image data is a major issue. So, we have proposed a novel technique for security of color image data by public-key cryptosystem or asymmetric cryptosystem. In this technique, we have developed security of color image data using RSA (Rivest-Shamir-Adleman) cryptosystem with two-dimensional discrete wavelet transform (2D-DWT). Earlier proposed schemes for security of color images designed on the basis of keys, but this approach provides security of color images with the help of keys and correct arrangement of RSA parameters. If the attacker knows about exact keys, but has no information of exact arrangement of RSA parameters, then the original information cannot be recovered from the encrypted data. Computer simulation based on standard example is critically examining the behavior of the proposed technique. Security analysis and a detailed comparison between earlier developed schemes for security of color images and proposed technique are also mentioned for the robustness of the cryptosystem.

  17. Alternative practices in curriculum design. Participation as a key factor and speaking out as right

    Directory of Open Access Journals (Sweden)

    Susana Barco

    2012-06-01

    Full Text Available During the 1990s, in the context of neo-liberal policies, curricular changes ocurred in Latin América which gave a leading role to technicians and experts in education, in the process of writing the curricular documents. Beyond the critiques these policies can receive, it is necessary to find alternative ways of elaborating curricular documents, based on democratic idea of teacher's real participation.In an action-research within the scope of a university and two experiences referred to in this work, different participative styles emerged, according to their particular circumstances. This work referred to these processes and its theoretical foundations, reporting alternative ways of curricular design based on teacher's participation and its different forms. The aim is to enhance how teachers as a social subject can 'stand up for themselves'and 'speak out' in the specific practice of writing curricular documents. Taking into account that teaching practices rewrite curricular documents, different dynamics in curricular change are possible, allowing adjusting and adapting realities in each institution, and propelling collaborative work.

  18. Nanomaterials towards fabrication of cholesterol biosensors: Key roles and design approaches.

    Science.gov (United States)

    Saxena, Urmila; Das, Asim Bikas

    2016-01-15

    Importance of cholesterol biosensors is already recognized in the clinical diagnosis of cardiac and brain vascular diseases as discernible from the enormous amount of research in this field. Nevertheless, the practical application of a majority of the fabricated cholesterol biosensors is ordinarily limited by their inadequate performance in terms of one or more analytical parameters including stability, sensitivity and detection limit. Nanoscale materials offer distinctive size tunable electronic, catalytic and optical properties which opened new opportunities for designing highly efficient biosensor devices. Incorporation of nanomaterials in biosensing devices has found to improve the electroactive surface, electronic conductivity and biocompatibility of the electrode surfaces which then improves the analytical performance of the biosensors. Here we have reviewed recent advances in nanomaterial-based cholesterol biosensors. Foremost, the diverse roles of nanomaterials in these sensor systems have been discussed. Later, we have exhaustively explored the strategies used for engineering cholesterol biosensors with nanotubes, nanoparticles and nanocomposites. Finally, this review concludes with future outlook signifying some challenges of these nanoengineered cholesterol sensors. Copyright © 2015 Elsevier B.V. All rights reserved.

  19. Trench angle: a key design factor for a deep trench superjunction MOSFET

    International Nuclear Information System (INIS)

    Kang, Hyemin; Lee, Jaegil; Lee, Kwangwon; Choi, Youngchul

    2015-01-01

    Why is the development of a deep trench superjunction (SJ) MOSFET above 600 V and under 8.0 mohm · cm 2 difficult? A deep trench SJ MOSFET is expected to have a low turn-on resistance because the post thermal process after the epitaxial process, which is normally used in a multi-step epitaxy structure, is unnecessary. When designing a deep trench SJ MOSFET, the trench angle is the most important factor because this determines the breakdown voltage (BV) and BV variations. In this paper, we investigated how the trench angle affects the BV and BV window as a condition of the possible thermal process. By employing a physical concept, ΔCharge, we explained why the maximum BV is decreased and the BV window is increased as the trench angle decreases. Also, we systematically scrutinized the transition of the vertical electric field by varying the trench angle. Furthermore, in a real case, the principle of the trench angle which contributes to the deviation of the charge imbalance and specific resistance of SJ is described. Finally, we discuss the challenge of SJ MOSFET development in the industry. (paper)

  20. Design Review Report for formal review of safety class features of exhauster system for rotary mode core sampling

    International Nuclear Information System (INIS)

    JANICEK, G.P.

    2000-01-01

    Report documenting Formal Design Review conducted on portable exhausters used to support rotary mode core sampling of Hanford underground radioactive waste tanks with focus on Safety Class design features and control requirements for flammable gas environment operation and air discharge permitting compliance

  1. Design Review Report for formal review of safety class features of exhauster system for rotary mode core sampling

    Energy Technology Data Exchange (ETDEWEB)

    JANICEK, G.P.

    2000-06-08

    Report documenting Formal Design Review conducted on portable exhausters used to support rotary mode core sampling of Hanford underground radioactive waste tanks with focus on Safety Class design features and control requirements for flammable gas environment operation and air discharge permitting compliance.

  2. Study of In-Pile test facility for fast reactor safety research: performance requirements and design features

    Energy Technology Data Exchange (ETDEWEB)

    Nonaka, N.; Kawatta, N.; Niwa, H.; Kondo, S.; Maeda, K

    1996-12-31

    This paper describes a program and the main design features of a new in-pile safety facility SERAPH planned for future fast reactor safety research. The current status of R and D on technical developments in relation to the research objectives and performance requirements to the facility design is given.

  3. Design and Fabrication Technique of the Key Components for Very High Temperature Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Ho Jin; Song, Ki Nam; Kim, Yong Wan

    2006-12-15

    The gas outlet temperature of Very High Temperature Reactor (VHTR) may be beyond the capability of conventional metallic materials. The requirement of the gas outlet temperature of 950 .deg. C will result in operating temperatures for metallic core components that will approach very high temperature on some cases. The materials that are capable of withstanding this temperature should be prepared, or nonmetallic materials will be required for limited components. The Ni-base alloys such as Alloy 617, Hastelloy X, XR, Incoloy 800H, and Haynes 230 are being investigated to apply them on components operated in high temperature. Currently available national and international codes and procedures are needed reviewed to design the components for HTGR/VHTR. Seven codes and procedures, including five ASME Codes and Code cases, one French code (RCC-MR), and on British Procedure (R5) were reviewed. The scope of the code and code cases needs to be expanded to include the materials with allowable temperatures of 950 .deg. C and higher. The selection of compact heat exchangers technology depends on the operating conditions such as pressure, flow rates, temperature, but also on other parameters such as fouling, corrosion, compactness, weight, maintenance and reliability. Welding, brazing, and diffusion bonding are considered proper joining processes for the heat exchanger operating in the high temperature and high pressure conditions without leakage. Because VHTRs require high temperature operations, various controlled materials, thick vessels, dissimilar metal joints, and precise controls of microstructure in weldment, the more advanced joining processes are needed than PWRs. The improved solid joining techniques are considered for the IHX fabrication. The weldability for Alloy 617 and Haynes 230 using GTAW and SMAW processes was investigated by CEA.

  4. Design and Fabrication Technique of the Key Components for Very High Temperature Reactor

    International Nuclear Information System (INIS)

    Lee, Ho Jin; Song, Ki Nam; Kim, Yong Wan

    2006-12-01

    The gas outlet temperature of Very High Temperature Reactor (VHTR) may be beyond the capability of conventional metallic materials. The requirement of the gas outlet temperature of 950 .deg. C will result in operating temperatures for metallic core components that will approach very high temperature on some cases. The materials that are capable of withstanding this temperature should be prepared, or nonmetallic materials will be required for limited components. The Ni-base alloys such as Alloy 617, Hastelloy X, XR, Incoloy 800H, and Haynes 230 are being investigated to apply them on components operated in high temperature. Currently available national and international codes and procedures are needed reviewed to design the components for HTGR/VHTR. Seven codes and procedures, including five ASME Codes and Code cases, one French code (RCC-MR), and on British Procedure (R5) were reviewed. The scope of the code and code cases needs to be expanded to include the materials with allowable temperatures of 950 .deg. C and higher. The selection of compact heat exchangers technology depends on the operating conditions such as pressure, flow rates, temperature, but also on other parameters such as fouling, corrosion, compactness, weight, maintenance and reliability. Welding, brazing, and diffusion bonding are considered proper joining processes for the heat exchanger operating in the high temperature and high pressure conditions without leakage. Because VHTRs require high temperature operations, various controlled materials, thick vessels, dissimilar metal joints, and precise controls of microstructure in weldment, the more advanced joining processes are needed than PWRs. The improved solid joining techniques are considered for the IHX fabrication. The weldability for Alloy 617 and Haynes 230 using GTAW and SMAW processes was investigated by CEA

  5. Evaluating the Operational Features of an Unconventional Dual-Bay U-Turn Design for Intersections.

    Directory of Open Access Journals (Sweden)

    Yun Xiang

    Full Text Available Median U-turn intersection treatment (MUTIT has been considered an alternative measure to reduce congestion and traffic conflict at intersection areas. The MUTIT is sometimes difficult to implement in the field because it requires wide median on arterials for U-turn vehicles. The objective of this study is to introduce an unconventional U-turn treatment (UUT for intersections which requires less median space but is also effective. The UUT has a dual-bay design with different turning radiuses for small and large vehicles. The VISSIM simulation model was developed to evaluate the operational features of the UUT. The model was calibrated using data collected from intersections in China. The capacity, delay and number of stops were evaluated and compared with the direct-left-turn (DLT for the same intersections. The results showed that the UUT significantly improved the operations at intersection areas, especially when volume/capacity ratio is small, and ratio of left-turn to through traffic is small. With the UUT, the capacity is increased by 9.81% to 10.38%, vehicle delay is decreased by 18.5% to 40.1%, and number of stops is decreased by 23.19% to 36.62%, when volume/capacity ratio is less than 0.50. The study also found that traffic efficiency could be further improved when the UUT is designed in conjunction with signal control. In the case, the UUT plus signalized control increases the capacity by 25% to 26.02%, decreases vehicle delay by 50.5% to 55.8%, and reduces number of stops by 69.5%, compared with the traditional DLT.

  6. Evaluating the Operational Features of an Unconventional Dual-Bay U-Turn Design for Intersections.

    Science.gov (United States)

    Xiang, Yun; Li, Zhibin; Wang, Wei; Chen, Jingxu; Wang, Hao; Li, Ye

    2016-01-01

    Median U-turn intersection treatment (MUTIT) has been considered an alternative measure to reduce congestion and traffic conflict at intersection areas. The MUTIT is sometimes difficult to implement in the field because it requires wide median on arterials for U-turn vehicles. The objective of this study is to introduce an unconventional U-turn treatment (UUT) for intersections which requires less median space but is also effective. The UUT has a dual-bay design with different turning radiuses for small and large vehicles. The VISSIM simulation model was developed to evaluate the operational features of the UUT. The model was calibrated using data collected from intersections in China. The capacity, delay and number of stops were evaluated and compared with the direct-left-turn (DLT) for the same intersections. The results showed that the UUT significantly improved the operations at intersection areas, especially when volume/capacity ratio is small, and ratio of left-turn to through traffic is small. With the UUT, the capacity is increased by 9.81% to 10.38%, vehicle delay is decreased by 18.5% to 40.1%, and number of stops is decreased by 23.19% to 36.62%, when volume/capacity ratio is less than 0.50. The study also found that traffic efficiency could be further improved when the UUT is designed in conjunction with signal control. In the case, the UUT plus signalized control increases the capacity by 25% to 26.02%, decreases vehicle delay by 50.5% to 55.8%, and reduces number of stops by 69.5%, compared with the traditional DLT.

  7. Stamp design effect on 100 nm feature size for 8 inch NanoImprint lithography

    International Nuclear Information System (INIS)

    Landis, S; Chaix, N; Gourgon, C; Perret, C; Leveder, T

    2006-01-01

    Sub-100 nm resolution on a 200 mm silicon stamp has been hot embossed into commercial Sumitomo NEB 22 resist. A single pattern, exposed with electron beam lithography, has been considered to define the stamp and thus make it possible to point out the impact of stamp design on the printing. These results may be considered as a first attempt to define rules to solve the proximity printing effects (PPEs). Moreover, a large range of initial resist thickness, from 56 to 506 nm, has been spin coated to assess the effect of polymer flow properties for the stamp cavity filling and the printed defects. A detailed analysis of the printed resist in dense hole patterns showed that the application volume conservation is enough to calculate the residual layer thickness as the height of the printed resist feature. Good accordance has been obtained between the theoretical approach and experimental results. Moreover, the impact of the pattern symmetry breakdown on mould deformation is clearly shown in this paper in the printed areas as well as in the unprinted areas

  8. The Design Features of the Double-Banked AMBIDEXTER Utilizing DUPIC Fuel

    Energy Technology Data Exchange (ETDEWEB)

    Ham, Tae Kyu [KHNP Central Research Institute, Daejeon (Korea, Republic of); Lee, Young Joon; Hong, Sung Taek [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Seo, Myung Hwan [Korea Radioactive Waste Agency, Daejeon (Korea, Republic of); Kwon, Tae An [KHNP, Daejeon (Korea, Republic of); Oh, Se Kee [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

    2016-10-15

    Since the on-site spent fuel storage capabilities at reactors in Korea are expected to be saturated in a few years, the government has been pressed to find a solution for the spent nuclear fuel. So far one of workable means for reducing the load would be utilizing DUPIC fuel cycle technology. The technology was developed through Korea-Canada-U.S. collaboration to utilize the LWR spent fuel for the CANDU reactor. However, by various sociopolitical reasons, the DUPIC technology has not been yet commercialized. As the other alternatives to use the DUPIC technology, Gen-IV reactors would be pertinent. In the following session, the design features of a molten salt reactor system that can burn DUPIC fuel are explained. The followings are derived as conclusions after considering all the factors; The AMDEC, compared to ORIGEN2 simulations, can calculate the nuclides concentration changes within 1% deviation in various core zones and reactor system components by using different library sets which are weighted with each neutron spectrum; Fuel-flow effects coupled with nuclear reactions is well reflected in the AMDEC.

  9. SCW Pressure-Channel Nuclear Reactors: Some Design Features and Concepts

    International Nuclear Information System (INIS)

    Duffey, R.B.; Pioro, I.L.; Gabaraev, B.A.; Kuznetsov, Yu. N.

    2006-01-01

    Concepts of nuclear reactors cooled with water at supercritical pressures were studied as early as the 1950's and 1960's in the USA and Russia. After a 30-year break, the idea of developing nuclear reactors cooled with supercritical water (SCW) became attractive again as the ultimate development path for water-cooling. The main objectives of using SCW in nuclear reactors are 1) to increase the thermal efficiency of modern nuclear power plants (NPPs) from 33 -- 35% to about 40 -- 45%, and 2) to decrease capital and operational costs and hence decrease electrical energy costs (∼$ 1000 US/kW). SCW NPPs will have much higher operating parameters compared to modern NPPs (pressure about 25 MPa and outlet temperature up to 625 deg. C), and a simplified flow circuit, in which steam generators, steam dryers, steam separators, etc., can be eliminated. Also, higher SCW temperatures allow direct thermo-chemical production of hydrogen at low cost, due to increased reaction rates. Pressure-channel SCW nuclear reactor concepts are being developed in Canada and Russia. Design features related to both channels and fuel bundles are discussed in this paper. Also, Russian experience with operating supercritical steam heaters at NPP is presented. The main conclusion is that development of SCW pressure-channel nuclear reactors is feasible and significant benefits can be expected over other thermal energy systems. (authors)

  10. Understanding the selection of core head design features to match precisely challenging well applications

    Energy Technology Data Exchange (ETDEWEB)

    Zambrana, Roberto; Sousa, J. Tadeu V. de; Antunes, Ricardo [Halliburton Servicos Ltda., Rio de Janeiro, RJ (Brazil)

    2008-07-01

    Reliable rock mechanical information is very important for optimum reservoir development. This information can help specialists to accurately estimate reserves, reservoir compaction, sand production, stress field orientation, etc. In all cases, the solutions to problems involving rock mechanics lead to significant cost savings. Consequently, it is important that the decisions be based on the most accurate information possible. For the describing rock mechanics, cores represent the major source of data and therefore should be of good quality. However, there are several well conditions that cause coring and core recovery to be difficult, for example: unconsolidated formations; laminated and fractured rocks; critical mud losses, etc. The problem becomes even worse in high-inclination wells with long horizontal sections. In such situations, the optimum selections of core heads become critical. This paper will discuss the most important design features that enable core heads to be matched precisely to various challenging applications. Cases histories will be used to illustrate the superior performance of selected core heads. They include coring in horizontal wells and in harsh well conditions with critical mud losses. (author)

  11. Design features and performance of the LAMPF high-intensity beam area

    International Nuclear Information System (INIS)

    Agnew, L.; Grisham, D.; Macek, R.J.; Sommer, W.F.; Werbeck, R.D.

    1983-01-01

    LAMPF is a multi-purpose high-intensity meson factory capable of producing a 1 mA beam of 800-MeV protons. The three target cells and the beam stop facilities in the high intensity area have many special design features that are required for operation in the presence of high heat loads and intense radiation fields where accessibility is extremely limited. Reliable targets, beam windows, beam stops, beam transport and diagnostic components, vacuum enclosures, and auxiliary systems have been developed. Sophisticated remote-handling systems are employed for maintenance. Complex protection systems have been developed to guard against damage caused by errant beam. Beam availability approaching 90% has been achieved at currents of 600 to 700 μA. A new facility for direct proton and neutron radiation effects studies will be installed in 1985. The new facility will provide an integrated spallation neutron flux of up to 5 x 10 17 m -2 s -1 and will anable proton irradiation studies in the primary beam

  12. How do the design features of health hackathons contribute to participatory medicine?

    Directory of Open Access Journals (Sweden)

    Karen Day

    2017-03-01

    Full Text Available The Hackathon concept is attracting interest as a vehicle for participatory development in both Health and Information systems. Publically available datasets, cloud based data storage, and increasingly sophisticated analytical methods, combined with user friendly development tools for mobile devices are inspiring innovation in the participatory medicine space. This has the potential to disrupt traditional methods and deliver solutions more rapidly, and in a form more likely to meet requirements. In health applications this involves putting the patient and their supports at the centre of design. This work contributes to solving the challenges involved in bringing a diverse cohort of designers, developers, problem owners, healthcare providers, patients, and citizens together to solve user-driven self-care problems using technology. We use a descriptive case study approach focussing on two weekend-long hackathons dubbed “Health Hackathon: Solving Self-care”. We gather thick data from multiple sources according to the process defined by Geertz (1994 first, to provide a rich picture of the role of hackathons in participatory medicine and second, to contribute evidence to the practise of running a hackathon. Some key originalities of our work include seeking more candid responses via self-serve interviews. Through this, controversially, we noted a marked emphasis on the creative process over concerns for privacy and ethics around the personal data cloud created by hackathon products. We build on existing theories of participatory medicine and emerging methodologies for conducting hackathons to provide evidence of the efficacy of the hacking approach both in terms of outcome and team dynamics. Through interviews, observation, twitter feeds and a pre-survey, we identify a number of success factors including (1 group size, (2 maturity of the idea, (3 level of involvement of a mentor, and (4 involvement of students. In addition we identify five skills

  13. Automatic feature design for optical character recognition using an evolutionary search procedure.

    Science.gov (United States)

    Stentiford, F W

    1985-03-01

    An automatic evolutionary search is applied to the problem of feature extraction in an OCR application. A performance measure based on feature independence is used to generate features which do not appear to suffer from peaking effects [17]. Features are extracted from a training set of 30 600 machine printed 34 class alphanumeric characters derived from British mail. Classification results on the training set and a test set of 10 200 characters are reported for an increasing number of features. A 1.01 percent forced decision error rate is obtained on the test data using 316 features. The hardware implementation should be cheap and fast to operate. The performance compares favorably with current low cost OCR page readers.

  14. Modelling Feature Interaction Patterns in Nokia Mobile Phones using Coloured Petri Nets and Design/CPN

    DEFF Research Database (Denmark)

    Lorentsen, Louise; Tuovinen, Antti-Pekka; Xu, Jianli

    2002-01-01

    ), WAP browsing, games, etc. All these features are packaged into a handset with a small screen and a special purpose keypad. The limited user interface and the seamless intertwining of logically separate features cause many problems in the software development of the user interface of mobile phones...

  15. Design and Realization of Music Retrieval System Based on Feature Content

    Directory of Open Access Journals (Sweden)

    Li Lei

    2015-01-01

    Full Text Available As computer technology develops rapidly, retrieval systems have also undergone great changes. People are no longer contented with singular retrieval means, but are trying many other ways to retrieve feature content. When it comes to music, however, the complexity of sound is still preventing its retrieval from moving further forward. To solve this problem, systematic analysis and study is carried out on music retrieval system based on feature content. A music retrieval system model based on feature content consisting of technical approaches for processing and retrieving of extraction symbols of music feature content is built and realized. An SML model is proposed and tested on two different types of song sets. The result shows good performance of the system. Besides, the shortfalls of the model are also noted and the future prospects of the music retrieval system based on feature content are outlined.

  16. Experimental Study and Computational Simulations of Key Pebble Bed Thermo-mechanics Issues for Design and Safety

    Energy Technology Data Exchange (ETDEWEB)

    Tokuhiro, Akira; Potirniche, Gabriel; Cogliati, Joshua; Ougouag, Abderrafi

    2014-07-08

    An experimental and computational study, consisting of modeling and simulation (M&S), of key thermal-mechanical issues affecting the design and safety of pebble-bed (PB) reactors was conducted. The objective was to broaden understanding and experimentally validate thermal-mechanic phenomena of nuclear grade graphite, specifically, spheres in frictional contact as anticipated in the bed under reactor relevant pressures and temperatures. The contact generates graphite dust particulates that can subsequently be transported into the flowing gaseous coolent. Under postulated depressurization transients and with the potential for leaked fission products to be adsorbed onto graphite 'dust', there is the potential for fission products to escape from the primary volume. This is a design safety concern. Furthermore, earlier safety assessment identified the distinct possibility for the dispersed dust to combust in contact with air if sufficient conditions are met. Both of these phenomena were noted as important to design review and containing uncertainty to warrant study. The team designed and conducted two separate effects tests to study and benchmark the potential dust-generation rate, as well as study the conditions under which a dust explosion may occure in a standardized, instrumented explosion chamber.

  17. Design and test performance of the ATLAS Feature Extractor trigger boards for the Phase-I Upgrade

    CERN Document Server

    Qian, Weiming; The ATLAS collaboration

    2016-01-01

    In Run 3, the ATLAS Level-1 Calorimeter Trigger will be augmented by an Electron Feature Extractor (eFEX), to identify isolated e/g and t particles, and a Jet Feature Extractor (jFEX), to identify energetic jets and calculate various local energy sums. Each module accommodates more than 420 differential signals that can operate at up to 12.8 Gb/s, some routed over 20 cm between FPGAs. Presented here are the module designs, the processes that have been adopted to meet the challenges associated with multi-Gb/s PCB design, and the results of tests that characterise the performance of these modules.

  18. Usability as the Key Factor to the Design of a Web Server for the CReF Protein Structure Predictor: The wCReF

    Directory of Open Access Journals (Sweden)

    Vanessa Stangherlin Machado Paixão-Cortes

    2018-01-01

    Full Text Available Protein structure prediction servers use various computational methods to predict the three-dimensional structure of proteins from their amino acid sequence. Predicted models are used to infer protein function and guide experimental efforts. This can contribute to solving the problem of predicting tertiary protein structures, one of the main unsolved problems in bioinformatics. The challenge is to understand the relationship between the amino acid sequence of a protein and its three-dimensional structure, which is related to the function of these macromolecules. This article is an extended version of the article wCReF: The Web Server for the Central Residue Fragment-based Method (CReF Protein Structure Predictor, published in the 14th International Conference on Information Technology: New Generations. In the first version, we presented the wCReF, a protein structure prediction server for the central residue fragment-based method. The wCReF interface was developed with a focus on usability and user interaction. With this tool, users can enter the amino acid sequence of their target protein and obtain its approximate 3D structure without the need to install all the multitude of necessary tools. In this extended version, we present the design process of the prediction server in detail, which includes: (A identification of user needs: aiming at understanding the features of a protein structure prediction server, the end user profiles and the commonly-performed tasks; (B server usability inspection: in order to define wCReF’s requirements and features, we have used heuristic evaluation guided by experts in both the human-computer interaction and bioinformatics domain areas, applied to the protein structure prediction servers I-TASSER, QUARK and Robetta; as a result, changes were found in all heuristics resulting in 89 usability problems; (C software requirements document and prototype: assessment results guiding the key features that wCReF must

  19. Feature Extraction

    CERN Document Server

    CERN. Geneva

    2015-01-01

    Feature selection and reduction are key to robust multivariate analyses. In this talk I will focus on pros and cons of various variable selection methods and focus on those that are most relevant in the context of HEP.

  20. Special features of the safety concept and design requirements applied for Angra-2 and 3

    International Nuclear Information System (INIS)

    Anon.

    1980-01-01

    The special features and requirements which have been applied by NUCLEN (Nuclebras Engenharia S/A) for Angra 2 and Angra 3 and which depart somewhat from the KWU (Kraftwerk Union) standard plant, are presented. (E.G.) [pt

  1. Assessment of severe accident prevention and mitigation features: PWR, large dry containment design

    International Nuclear Information System (INIS)

    Perkins, K.R.; Hsu, C.J.; Lehner, J.R.; Luckas, W.J.; Cho, N.; Fitzpatrick, R.G.; Pratt, W.T.; Eltawila, F.; Maly, J.A.

    1988-07-01

    Plant features and operator actions which have been found to be important in either preventing or mitigating severe accidents in PWRs with large dry containments have been identified. These features and actions were developed from insights derived from reviews of risk assessments performed specifically for the Zion plant and from assessments of other relevant studies. Accident sequences that dominate the core-damage frequency and those accident sequences that are of potentially high consequence were identified. Vulnerabilities of the large dry containment to severe accident containment loads were also identified. In addition, those features of a PWR with a large dry containment, which are important for preventing core damage and are available for mitigating fission-product release to the environment were identified. The report is issued to provide focus to the analyst examining an individual plant. The report calls attention to plant features and operator actions and provides a list of deterministic tributes for assessing those features and actions found to be helpful in reducing the overall risk for Zion and other PWRs with large dry containments. Thus, the guidance is offered as a resource in examining the subject plant to determine if the same, or similar, plant features and operator actions will be of value in reducing overall plant risk. This report is intended to serve solely as guidance

  2. Assessment of severe accident prevention and mitigation features: PWR, ice-condenser containment design

    International Nuclear Information System (INIS)

    Hsu, C.J.; Perkins, K.R.; Luckas, W.J.; Fitzpatrick, R.G.; Cho, N.; Lehner, J.R.; Pratt, W.T.; Eltawila, F.; Maly, J.A.

    1988-07-01

    Plant features and operator actions which have been found to be important in either preventing and mitigating severe accidents in PWRs with ice-condenser containments have been identified. Thus features and actions were developed from insights derived from reviews of risk assessments performed specifically for the Sequoyah plant and from assessments of other relevant studies. Accident sequences that dominate the core-damage frequency and those accident sequences that are of potentially high consequence were identified. Vulnerabilities of the ice-condenser containment to sever accident containment loads were also identified. In addition, those features of a PWR with an ice-condenser containment, which are important for preventing core damage and are available for mitigating fission-product release to the environment were identified. This report is issued to provide focus to an analyst examining an individual plant. The report calls attention to plant features and operator actions and provides a list of deterministic attributes for assessing those features and actions found to be helpful in reducing the overall risk for Sequoyah and other PWRs with ice-condenser containments. Thus, the guidance is offered as a resource in examining the subject plant to determine if the same, or similar, plant features and operator actions will be of value in reducing overall plant risk. This report is intended to serve solely as guidance. 14 tabs

  3. Assessment of severe accident prevention and mitigation features: BWR, Mark II containment design

    International Nuclear Information System (INIS)

    Lehner, J.R.; Hsu, C.J.; Eltawila, F.; Perkins, K.R.; Luckas, W.J.; Fitzpatrick, R.G.; Pratt, W.T.

    1988-07-01

    Plant features and operator actions, which have been found to be important in either preventing or mitigating severe accidents in BWRs with Mark II containments (BWR Mark II's) have been identified. These features and actions were developed from insights derived from reviews of in-depth risk assessments performed specifically for the Limerick and Shoreham plants and from other relevant studies. Accident sequences that dominate the core-damage frequency and those accident sequences that are of potentially high consequence were identified. Vulnerabilities of the BWR Mark II to severe-accident containment loads were also noted. In addition, those features of a BWR Mark II, which are important for preventing core damage and are available for mitigating fission-product release to the environment were also identified. This report is issued to provide focus to an analyst examining an individual plant. This report calls attention to plant features and operator actions and provides a list of deterministic attributes for assessing those features and actions found to be helpful in reducing the overall risk for Mark II plants. Thus, the guidance is offered as a resource in examining the subject plant to determine if the same, or similar, plant features and operator actions will be of value in reducing overall plant risk. This report is intended to serve solely as guidance

  4. Data-driven technology for engineering systems health management design approach, feature construction, fault diagnosis, prognosis, fusion and decisions

    CERN Document Server

    Niu, Gang

    2017-01-01

    This book introduces condition-based maintenance (CBM)/data-driven prognostics and health management (PHM) in detail, first explaining the PHM design approach from a systems engineering perspective, then summarizing and elaborating on the data-driven methodology for feature construction, as well as feature-based fault diagnosis and prognosis. The book includes a wealth of illustrations and tables to help explain the algorithms, as well as practical examples showing how to use this tool to solve situations for which analytic solutions are poorly suited. It equips readers to apply the concepts discussed in order to analyze and solve a variety of problems in PHM system design, feature construction, fault diagnosis and prognosis.

  5. How do different cigarette design features influence the standard tar yields of popular cigarette brands sold in different countries?

    Science.gov (United States)

    O'Connor, R J; Hammond, D; McNeill, A; King, B; Kozlowski, L T; Giovino, G A; Cummings, K M

    2008-09-01

    To examine the associations among cigarette design features and tar yields of leading cigarette brands sold in the United States, Canada, Australia and the United Kingdom. Government reports and numbers listed on packs were used to obtain data on International Organization for Standardization (ISO)/Federal Trade Commission (FTC) yields for the tar of 172 cigarette varieties sold in the United States, Canada, Australia and the United Kingdom. We used standardised methods to measure the following 11 cigarette design parameters: filter ventilation, cigarette pressure drop, filter pressure drop, tobacco rod length, filter length, cigarette diameter, tipping paper length, tobacco weight, filter weight, rod density and filter density. Filter ventilation was found to be the predominant design feature accounting for the variations between brands in ISO/FTC tar yields in each of the four countries. After accounting for filter ventilation, design parameters such as overwrap length, tobacco weight and rod density played comparatively minor roles in determining tar yields. Variation in ISO/FTC tar yields are predicted by a limited set of cigarette design features, especially filter ventilation, suggesting that governments should consider mandatory disclosure of cigarette design parameters as part of comprehensive tobacco product regulations.

  6. A novel edge based embedding in medical images based on unique key generated using sudoku puzzle design.

    Science.gov (United States)

    Santhi, B; Dheeptha, B

    2016-01-01

    The field of telemedicine has gained immense momentum, owing to the need for transmitting patients' information securely. This paper puts forth a unique method for embedding data in medical images. It is based on edge based embedding and XOR coding. The algorithm proposes a novel key generation technique by utilizing the design of a sudoku puzzle to enhance the security of the transmitted message. The edge blocks of the cover image alone, are utilized to embed the payloads. The least significant bit of the pixel values are changed by XOR coding depending on the data to be embedded and the key generated. Hence the distortion in the stego image is minimized and the information is retrieved accurately. Data is embedded in the RGB planes of the cover image, thus increasing its embedding capacity. Several measures including peak signal noise ratio (PSNR), mean square error (MSE), universal image quality index (UIQI) and correlation coefficient (R) are the image quality measures that have been used to analyze the quality of the stego image. It is evident from the results that the proposed technique outperforms the former methodologies.

  7. The Pedagogical, Linguistic, and Content Features of Popular English Language Learning Websites in China: A Framework for Analysis and Design

    Science.gov (United States)

    Kettle, Margaret; Yuan, Yifeng; Luke, Allan; Ewing, Robyn; Shen, Huizhong

    2012-01-01

    As increasing numbers of Chinese language learners choose to learn English online, there is a need to investigate popular websites and their language learning designs. This paper reports on the first stage of a study that analyzed the pedagogical, linguistic, and content features of 25 Chinese English Language Learning (ELL) websites ranked…

  8. Recommendations for sex/gender neuroimaging research: key principles and implications for research design, analysis, and interpretation

    Science.gov (United States)

    Rippon, Gina; Jordan-Young, Rebecca; Kaiser, Anelis; Fine, Cordelia

    2014-01-01

    Neuroimaging (NI) technologies are having increasing impact in the study of complex cognitive and social processes. In this emerging field of social cognitive neuroscience, a central goal should be to increase the understanding of the interaction between the neurobiology of the individual and the environment in which humans develop and function. The study of sex/gender is often a focus for NI research, and may be motivated by a desire to better understand general developmental principles, mental health problems that show female-male disparities, and gendered differences in society. In order to ensure the maximum possible contribution of NI research to these goals, we draw attention to four key principles—overlap, mosaicism, contingency and entanglement—that have emerged from sex/gender research and that should inform NI research design, analysis and interpretation. We discuss the implications of these principles in the form of constructive guidelines and suggestions for researchers, editors, reviewers and science communicators. PMID:25221493

  9. An overview of some basic design features of Koeberg Nuclear Power Station highlighting how regulatory requirements can influence design

    International Nuclear Information System (INIS)

    Morrison, A.R.

    1985-01-01

    The paper attempts to show that licensing requirements significantly influence the design of nuclear power plants. The French designed Pressurised Water Reactor system adopted by Escom at Koeberg has its origins in the General Design Criteria set out in the American Code of Federal Regulations document 10CFR50. Three of the General Design Criteria have been selected for illustrating how the requirements have influenced Koeberg in terms of design, both from a hardware and software view point. The requirements of the criteria on quality standard and records are to a certain extent reflected in the Licensing Branch Guide developed by the Atomic Energy Corporation to address quality assurance. The criterion on containment design sets requirements in respect of containment design which are incorporated in the Koeberg design. The criterion on electric power systems sets many of the basic design requirements for the electrical power supply systems inside and outside the station. The existence of the criterion led Escom to introduce changes in the transmission network to meet the requirements in respect of the independent criteria for the grid connections

  10. Design reuse in product shape modeling : A study of freeform feature reuse by signal processing techniques

    NARCIS (Netherlands)

    Wang, C.

    2005-01-01

    Lack of facilities in supporting design reuse is a serious problem in product shape modeling, especially in computer-aided design systems. This becomes a bottleneck of fast shape conceptualization and creation in consumer product design, which consequently prohibits creativity and innovation. In the

  11. Recriticality, a Key Phenomenon to Investigate in Core Disruptive Accident Scenarios of Current and Future Fast Reactor Designs

    International Nuclear Information System (INIS)

    Maschek, W.; Rineiski, A.; Flad, M.; Kriventsev, V.; Gabrielli, F.; Morita, K.

    2012-01-01

    Final comments and conclusions: • Modern plants, should have performed better under Fukushima type event. • In future fast reactor systems significantly higher active and passive safety features are installed, which should cope with events like Fukushima. • One important lesson: put a focus on rare initiators, accident routes and consequences that are neither expected nor have been observed, events that are categorized under ‘black swans’. • Importance of severe accident research demonstrated - both analytically and experimentally for assessing and interpreting accident scenarios and developments. Precondition for developing preventive & mitigative safety measures. Passive safety measures are in the focus of advanced design options and must work under conditions of multiple loads and aggravating events. • Fast reactor systems behavior as the SFR under severe accident conditions: – In fast spectrum systems as the SFR the core is not in its neutronically most reactive configuration and SFRs may be loaded with MAs for waste management; – Recriticalities have a high probability because of the higher enrichment levels; – Short time scales have to be envisioned for core melt-down; – Decay heat levels might be significantly higher, if MA bearing fuel is involved. • Improve design by measures for prevention and/or mitigation of recriticalities; – High reliability of simulations required for proof; • Assessment of fuel relocated on peripheral structures; • Preventive/mitigating measures should not replace containment measures

  12. Design of a hybrid reconfigurable Software Defined Radio transceiver based on frequency shift keying using multiple encoding schemes

    Directory of Open Access Journals (Sweden)

    Nikhil Marriwala

    2016-03-01

    The aim of this paper was to analyze Frequency Shift Keying (FSK Transceiver built using Laboratory Virtual Instrumentation Engineering Workbench (LabVIEW and to measure the reduction in data errors in the presence of Forward Error Correction (FEC channel coding algorithms namely the Convolution and the Turbo Codes. Through this design a graphical representation of Bit Error Rate (BER vs Eb/N0 where (Eb is Energy per bit and (N0 is Spectral noise density has been given in the presence of Additive White Gaussian Noise (AWGN introduced in the channel. FSK is widely used for data transmission over band pass channels; hence, we have chosen FSK for the implementation of SDR. The SDR transceiver module designed has been fully implemented and has the ability to navigate over a wide range of frequencies with programmable channel bandwidth and modulation characteristics. We are able to build an interactive FSK based SDR transceiver in a shorter time with the use of LabVIEW. The outputs achieved show a low BER for very high data rates in the presence of AWGN noise.

  13. Benefit-feature segmentation: A tool for the design of a supply-chain strategy

    NARCIS (Netherlands)

    Canever, M.D.; Trijp, van J.C.M.; Lans, van der I.A.

    2007-01-01

    Abstract: Purpose ¿ This paper aims to assess the effectiveness of different segmentation schemes as the basis of marketing strategy, with particular respect to supply-chain decisions, and to propose a new procedure capable of combining benefits sought and features available.

  14. The Multi-Feature Hypothesis: Connectionist Guidelines for L2 Task Design

    Science.gov (United States)

    Moonen, Machteld; de Graaff, Rick; Westhoff, Gerard; Brekelmans, Mieke

    2014-01-01

    This study focuses on the effects of task type on the retention and ease of activation of second language (L2) vocabulary, based on the multi-feature hypothesis (Moonen, De Graaff, & Westhoff, 2006). Two tasks were compared: a writing task and a list-learning task. It was hypothesized that performing the writing task would yield higher…

  15. Perception Of "Features" And "Objects": Applications To The Design Of Instrument Panel Displays

    Science.gov (United States)

    Poynter, Douglas; Czarnomski, Alan J.

    1988-10-01

    An experiment was conducted to determine whether socalled feature displays allow for faster and more accurate processing compared to object displays. Previous psychological studies indicate that features can be processed in parallel across the visual field, whereas objects must be processed one at a time with the aid of attentional focus. Numbers and letters are examples of objects; line orientation and color are examples of features. In this experiment, subjects were asked to search displays composed of up to 16 elements for the presence of specific elements. The ability to detect, localize, and identify targets was influenced by display format. Digital errors increased with the number of elements, the number of targets, and the distance of the target from the fixation point. Line orientation errors increased only with the number of targets. Several other display types were evaluated, and each produced a pattern of errors similar to either digital or line orientation format. Results of the study were discussed in terms of Feature Integration Theory, which distinguishes between elements that are processed with parallel versus serial mechanisms.

  16. Metamorphic rock-hosted orogenic gold deposit style at Bombana (Southeast Sulawesi and Buru Island (Maluku: Their key features and significances for gold exploration in Eastern Indonesia

    Directory of Open Access Journals (Sweden)

    Arifudin Idrus

    2017-06-01

    are identified. Early quartz veins are segmented, sigmoidal discontinuous and parallel to the foliation of the host rock. This generation of quartz veins is characterized by crystalline relatively clear quartz, and weakly mineralized with low sulfide and gold contents. The second type of quartz veins occurs within the ‘mineralized zone’ of about 100 m in width and ~1,000 m in length. Gold mineralization is intensely overprinted by argillic alteration. The mineralization-alteration zone is probably parallel to the mica schist foliation and strongly controlled by N-S or NE-SW-trending structures. Gold-bearing quartz veins are characterized by banded texture particularly following host rock foliation and sulphide banding, brecciated and rare bladed-like texture. Alteration types consist of propylitic (chlorite, calcite, sericite, argillic and carbonation represented by graphite banding and carbon flakes. Ore mineral comprises pyrite, native gold, pyrrhotite, and arsenopyrite. Cinnabar and stibnite are present in association with gold. Ore chemistry indicates that 11 out of 15 samples yielded more than 1 g/t Au, in which 6 of them graded in excess of 3 g/t Au. All high-grade samples are composed of limonite or partly contain limonitic material. This suggests the process of supergene enrichment. Interestingly, most of the high-grade samples contain also high concentrations of As (up to 991ppm, Sb (up to 885ppm, and Hg (up to 75ppm. Fluid inclusions in both quartz vein types consist of 4 phases including L-rich, V-rich, L-V-rich and L1-L2-V (CO2-rich phases. The mineralizing hydrothermal fluid typically is CO2-rich, of moderate temperature (300-400 ºC, and low salinity (0.36 to 0.54 wt.% NaCl eq. Based on those key features, gold mineralization in Bombana and Buru Island tends to meet the characteristics of orogenic, mesothermal types of gold deposit. Metamorphic rock-hosted gold deposits could represent the new targets for gold exploration particularly in Eastern

  17. A study on the fusion reactor - A study on the design feature of fusion reactor divertor

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Kyung Jin [Chosun University, Kwangju (Korea, Republic of); Paek, Won Pil; Jang, Soon Hong [Korea Advanced Institute of Science and Technology, Taejon (Korea, Republic of); Sim, Young Jae [Kyungsang University, Jinju (Korea, Republic of)

    1996-09-01

    The contents and scope of the project can be summarized as, - study on the trend of divertor design - study on characteristics of coolant materials - study on characteristics of divertor materials - study on the thermal analysis method of divertor design. 36 refs., 12 tabs., 16 figs. (author)

  18. Design Models as Emergent Features: An Empirical Study in Communication and Shared Mental Models in Instructional

    Science.gov (United States)

    Botturi, Luca

    2006-01-01

    This paper reports the results of an empirical study that investigated the instructional design process of three teams involved in the development of an e-­learning unit. The teams declared they were using the same fast-­prototyping design and development model, and were composed of the same roles (although with a different number of SMEs).…

  19. Characteristic features of the core design of high-temperature reactors

    International Nuclear Information System (INIS)

    Brandes, S.; Lohnert, G.

    1975-01-01

    Following a survey on the possible applications of the HTGR depending on the height of the gas exiting temperatures, the core design for both of the fuel element concepts 'sphere' and 'block' is dealt with. The particularities arising from the multiple refueling and the one-way fueling in the design for spherical fuel elements are discussed. (UA/LH) [de

  20. REPOSITORY LAYOUT SUPPORTING DESIGN FEATURE NO.13 - WASTE PACKAGE SELF SHIELDING

    International Nuclear Information System (INIS)

    Owen, J.

    1999-01-01

    The objective of this analysis is to develop a repository layout, for Feature No. 13, that will accommodate self-shielding waste packages (WP) with an areal mass loading of 25 metric tons of uranium per acre (MTU/acre). The scope of this analysis includes determination of the number of emplacement drifts, amount of emplacement drift excavation required, and a preliminary layout for illustrative purposes

  1. Concept design and alternate arrangements of orbiter mid-deck habitability features

    Science.gov (United States)

    Church, R. A.; Ciciora, J. A.; Porter, K. L.; Stevenson, G. E.

    1976-01-01

    The evaluations and recommendations for habitability features in the space shuttle orbiter mid-deck are summarized. The orbiter mission plans, the mid-deck dimensions and baseline arrangements along with crew compliments and typical activities were defined. Female and male anthropometric data based on zero-g operations were also defined. Evaluations of baseline and alternate feasible concepts provided several recommendations which are discussed.

  2. A study of design features of civil works of nuclear installations facilitating their eventual refurbishing, renewal, dismantling or demolition

    International Nuclear Information System (INIS)

    Paton, A.A.; Benwell, P.; Irwin, T.F.; Hunter, I.

    1984-03-01

    This report describes a study that has been carried out to identify civil engineering features which could be incorporated in future gas cooled and light water cooled nuclear power plants to facilitate their decommissioning. The report reviews the problems likely to be met in decommissioning present day nuclear power plants and concludes that there is a number of such features which could be introduced in future designs to overcome or eliminate the problems. The report identifies and describes these features and recommends that further work be carried out to confirm their feasibility. The study briefly considered the possibility of refurbishing nuclear plants and concluded that this is not a realistic option in present circumstances. (author)

  3. Design data and safety features of commercial nuclear power plants including cumulative index for Volumes I--VI

    International Nuclear Information System (INIS)

    Heddleson, F.A.

    1977-01-01

    Design data, safety features, and site characteristics are summarized for 12 nuclear power units in 6 power stations in the United States. Six pages of data are presented for each station, consisting of thermal-hydraulic and nuclear factors, containment features, emergency-core-cooling systems, site features, circulating water system data, and miscellaneous factors. In addition, an aerial perspective is presented for each plant. This volume covers plants with docket numbers 50-553 through 50-569 (Phipps Bend, Black Fox, Yellow Creek, and NEP) and two earlier plants not previously reported--Hope Creek (50-354, 50-355) and WPPSS 1 and 4 (50-460, 50-513). Indexes for this volume and the five earlier volumes are presented in three forms--by docket number, by plant name, and by participating utility

  4. [The morphological features of skin wounds inflicted by joinery hand saws designed for different types of sawing].

    Science.gov (United States)

    Sarkisian, B A; Azarov, P A

    2014-01-01

    The objective of the present work was to study the morphological features of skin wounds inflicted by joinery hand saws designed for longitudinal, transverse, and mixed sawing. A total of 60 injuries to the thigh skin inflicted by the recurring and reciprocating saw movements were simulated. The hand saws had 5 mm high "sharp" and "blunt"-tipped teeth. The analysis of the morphological features of the wounds revealed differences in their length and depth, shape of edge cuts and defects, and the relief of the walls depending on the sawtooth sharpness and the mode of sawing. It is concluded that morphological features of the wounds may be used to determine the type of the saw, the sharpness of its teeth, the direction and frequency of its movements.

  5. Conceptual Design of Hybrid Safety Features for NPP by Utilizing Solar Updraft Tower

    Energy Technology Data Exchange (ETDEWEB)

    Song, Sub Lee [Handong Global University, Pohang (Korea, Republic of); Choi, Young Jae; Kim, Yong Jin [KAIST, Daejeon (Korea, Republic of); Park, Hyo Chan; Park, Youn Won [BEES, Daejeon (Korea, Republic of)

    2016-05-15

    In this study, hybrid safety features for NPP with solar updraft tower (SUT) is conceptually suggested to cope with loss of ultimate heat sink accident. The hybrid safety features utilizing SUT target NPPs in seashore of Arabian Gulf. Usually NPPs are constructed near seashore to utilize sea water as an ultimate heat sink. Residual heat or decay heat of nuclear reactor will diffuse into the ocean through the condenser. NPPs in Middle East are expected to be placed in seashore of Arabian Gulf. The NPP site of Barakah is an actual example. For NPPs in seashore of Arabian Gulf, an additional safety concern should be considered. Arabian Gulf is the largest oil transporting route in the world. The oil spill risk in Arabian Gulf will be the largest simultaneously. Unfortunately, not like other oceans, Arabian Gulf is a kind of closed ocean which does not have strong ocean currents connected to out of the gulf. If once oil spill is occurred, its influence can be propagated more than our expectation. The spilled oil also can affect to NPPs in seashore by covering surfaces of condenser. It will directly cause loss of ultimate heat sink. The hybrid safety features of SUT system are expected to aid normal operation of safety system and mitigate consequence of severe accident. Detail analysis and technology development is ongoing now.

  6. Conceptual Design of Hybrid Safety Features for NPP by Utilizing Solar Updraft Tower

    International Nuclear Information System (INIS)

    Song, Sub Lee; Choi, Young Jae; Kim, Yong Jin; Park, Hyo Chan; Park, Youn Won

    2016-01-01

    In this study, hybrid safety features for NPP with solar updraft tower (SUT) is conceptually suggested to cope with loss of ultimate heat sink accident. The hybrid safety features utilizing SUT target NPPs in seashore of Arabian Gulf. Usually NPPs are constructed near seashore to utilize sea water as an ultimate heat sink. Residual heat or decay heat of nuclear reactor will diffuse into the ocean through the condenser. NPPs in Middle East are expected to be placed in seashore of Arabian Gulf. The NPP site of Barakah is an actual example. For NPPs in seashore of Arabian Gulf, an additional safety concern should be considered. Arabian Gulf is the largest oil transporting route in the world. The oil spill risk in Arabian Gulf will be the largest simultaneously. Unfortunately, not like other oceans, Arabian Gulf is a kind of closed ocean which does not have strong ocean currents connected to out of the gulf. If once oil spill is occurred, its influence can be propagated more than our expectation. The spilled oil also can affect to NPPs in seashore by covering surfaces of condenser. It will directly cause loss of ultimate heat sink. The hybrid safety features of SUT system are expected to aid normal operation of safety system and mitigate consequence of severe accident. Detail analysis and technology development is ongoing now

  7. Man-machine interface in a submarine command and weapon control system: features and design experience

    Directory of Open Access Journals (Sweden)

    Johan H. Aas

    1989-01-01

    Full Text Available Important man-machine interface (MMI issues concerning a submarine command and weapon control system (CWCS such as crew organization, automation level and decision support are discussed in this paper. Generic submarine CWCS functions and operating conditions are outlined. Detailed, dynamic and real-time prototypes were used to support the MMI design. The prototypes are described and experience with detailed prototyping is discussed. Some of the main interaction principles are summarized and a restricted example of the resulting design is given. Our design experience and current work have been used to outline future perspectives of MMI design in naval CWCSs. The need for both formal and experimental approaches is emphasized.

  8. IAEA Technical Meeting on Innovative Fast Reactor Designs with Enhanced Negative Reactivity Feedback Features. Working Material

    International Nuclear Information System (INIS)

    2012-01-01

    The objective of the TM was to review and discuss the safety characteristics and the performances of the core of innovative fast reactor concepts, as well as to present the ongoing R&D activities in the area of core design and advanced simulation tools and methods for fast reactor core physics analysis. The focus was on fast spectrum cores optimized for actinide utilization and transmutation and, in particular, on core designs with enhanced negative reactivity feedback effects

  9. Effects of stick design features on perceptions of characteristics of cigarettes.

    Science.gov (United States)

    Borland, Ron; Savvas, Steven

    2013-09-01

    To examine the extent (if any) that cigarette stick dimension, tipping paper design and other decorative design/branding have on Australian smokers' perceptions of those cigarettes. An internet survey of 160 young Australian adult ever-smokers who were shown computer images of three sets of cigarette sticks--five sticks of different lengths and diameters (set A), five sticks with different tipping paper design (set B) and four sticks of different decorative design (set C). Branding was a between-subjects randomised condition for set C. For each set, respondents ranked sticks on most and least attractive, highest and lowest quality and strongest and weakest taste. Cigarette sticks were perceived as different on attractiveness, quality and strength of taste. Standard stick length/diameter was perceived as the most attractive and highest quality stick, with men more inclined to rate a slim stick as less attractive. A stick with a cork-patterned tipping paper and a gold band was seen as most attractive, of highest quality and strongest in taste compared to other tipping designs. Branded sticks were seen as more attractive, higher in quality and stronger tasting than non-branded designs, regardless of brand, although the effects were stronger for a prestige compared with a budget brand. Characteristics of the cigarette stick affect smokers' perceptions of the attributes of those cigarettes and thus are a potential means by which product differentiation can occur. A comprehensive policy to eliminate promotional aspects of cigarette design and packaging needs to include rules about stick design.

  10. IAEA Technical Meeting on Innovative Fast Reactor Designs with Enhanced Negative Reactivity Feedback Features. Presentations

    International Nuclear Information System (INIS)

    2012-01-01

    The objective of the TM is to review and discuss the safety characteristics and the performances of the core of innovative fast reactor concepts, as well as to present the ongoing R&D activities in the area of core design and advanced simulation tools and methods for fast reactor core physics analysis. The focus is on fast spectrum cores optimized for actinide utilization and transmutation and, in particular, on core designs with enhanced negative reactivity feedback effects

  11. EDUCATIONAL NETWORK RESOURCES IN JOURNALISM AND PUBLISHING: FEATURES OF THE SITES' CONTENT AND DESIGN

    Directory of Open Access Journals (Sweden)

    Hanna A. Zenzina

    2012-12-01

    Full Text Available The article deals with the concept of electronic educational resource, its importance for the orientation of students in cyberspace, the basic requirements for the design and content of educational resources eligibility criteria standards. Filed benefits of having their own educational resource for high school. Singled out the importance of the interaction of educational resources with social networks. Detected differences and similarities of design and content of educational resources of Kyiv Universities in journalism and publishing.

  12. Special Features of Using Secondary Materials in the Interior Design of Public Dining Establishments

    Science.gov (United States)

    Kuznetsova, Irina; Hapchuk, Olena; Lukinov, Vitaly

    2017-10-01

    This article analyses the latest publications studying the use and practical application of secondary resources as raw materials in design. This analysis is based on the list of secondary resources and their applications in interior decoration. In particular, the interiors of public catering enterprises were analysed. Restaurants with different functional purposes that were classified into several categories with specific peculiarities of interior design were identified. This article presents and describes different types of public catering enterprises based on those categories. The interior design of a public catering enterprise is regarded as a considerably complex system. Different types of secondary materials were reviewed to identify the most frequently used materials for interior space design. This article describes the main peculiarities of the use of secondary materials and presents examples of their practical application. The function of secondary materials in the interior design of public catering enterprises were detected and reviewed. On the basis of the analysis, several directions for the practical application of our results in the field of public catering enterprise design were suggested.

  13. A 5.2/5.8 GHz Dual Band On-Off Keying Transmitter Design for Bio-Signal Transmission

    Science.gov (United States)

    Wu, Chang-Hsi; You, Hong-Cheng; Huang, Shun-Zhao

    2018-02-01

    An architecture of 5.2/5.8-GHz dual-band on-off keying (DBOOK) modulated transmitter is designed in a 0.18-μm CMOS technology. The proposed DBOOK transmitter is used in the biosignal transmission system with high power efficiency and small area. To reduce power consumption and enhance output swing, two pairs of center-tapped transformers are used as both LC tank and source grounding choke for the designed voltage controlled oscillator (VCO). Switching capacitances are used to achieve dual band operations, and a complemented power combiner is used to merge the differential output power of VCO to a single-ended output. Besides, the linearizer circuits are used in the proposed power amplifier with wideband output matching to improve the linearity both at 5.2/5.8-GHz bands. The designed DBOOK transmitter is implemented by dividing it into two chips. One chip implements the dual-band switching VCO and power combiner, and the other chip implements a linear power amplifier including dual-band operation. The first chip drives an output power of 2.2mW with consuming power of 5.13 mW from 1.1 V supply voltage. With the chip size including pad of 0.61 × 0.91 m2, the measured data rate and transmission efficiency attained are 100 Mb/s and 51 pJ/bit, respectively. The second chip, for power enhanced mode, exhibits P1 dB of -9 dBm, IIP3 of 1 dBm, the output power 1 dB compression point of 12.42 dBm, OIP3 of about 21 dBm, maximum output power of 17.02/16.18 dBm, and power added efficiency of 17.13/16.95% for 5.2/ 5.8 GHz. The chip size including pads is 0:693 × 1:084mm2.

  14. Design of Nonwoven Carpets to Upgrade Sound Isolation Features in Automobiles

    Directory of Open Access Journals (Sweden)

    Atakan Raziye

    2014-12-01

    Full Text Available With the increases of the expected properties of textile products, better and advanced new designs are being created. Textiles used in vehicles are increasing, and the current performance of the expectations bar is determined by automobile manufacturers. While meeting the expectations of users in the vehicle mechanically, but also disturbing the user during operation of the mechanical properties of this ratio should be minimized. This study was intended to minimize sound transmission of nonwoven textile components, which are used in cars as silencer parts. For that purpose, four different models were developed in this study. First model consists of three designs for baggage carpets. Second model has six designs for floor coverings. Third model comprises two designs inner dash felt and finally fourth model includes two designs of hood liners. The acoustical absorption coefficients and transmission loss of these carpets were tested and evaluated in the frequency range of 16-6300 Hz. The measurements demonstrated that nonwoven layer is a very significant and effective part of a carpet due to its contribution in the sound isolation. With this study, it has been determined which layer has better performance on sound absorption and transmission loss among different carpet types. A combination of heavy layer and nonwoven layer carpets is found to be benefit for noise and sound insulation.

  15. Safety design features for current UK advanced gas-cooled reactors

    Energy Technology Data Exchange (ETDEWEB)

    Yellowlees, J. M.; Cobb, E. C. [Nuclear Power Co. (Risley) Ltd. (UK)

    1981-01-15

    The nuclear power stations planned for Heysham II and Torness will each have twin 660 MW(e) Advanced Gas-cooled Reactors (AGR) based on the design of those which have been operating at Hinkley Point 'B' and Hunterston 'B' since 1976. This paper has described the way in which the shutdown and cooling systems for the Heysham II and Torness AGRs have been selected in order to meet current UK safety requirements. Fault tree analyses have been used to identify the credible fault sequences, the probabilities of which have been calculated. By this means the relative importance of the various protective systems has been established and redundancy and reliability requirements identified. This systematic approach has led to a balanced design giving protection over the complete spectrum of fault sequences. Current safety requirements for thermal reactors in the UK and particular requirements in the design of the Heysham II and Torness reactors are discussed.

  16. Safety design features for current UK advanced gas-cooled reactors

    International Nuclear Information System (INIS)

    Yellowlees, J.M.; Cobb, E.C.

    1981-01-01

    The nuclear power stations planned for Heysham II and Torness will each have twin 660 MW(e) Advanced Gas-cooled Reactors (AGR) based on the design of those which have been operating at Hinkley Point 'B' and Hunterston 'B' since 1976. This paper has described the way in which the shutdown and cooling systems for the Heysham II and Torness AGRs have been selected in order to meet current UK safety requirements. Fault tree analyses have been used to identify the credible fault sequences, the probabilities of which have been calculated. By this means the relative importance of the various protective systems has been established and redundancy and reliability requirements identified. This systematic approach has led to a balanced design giving protection over the complete spectrum of fault sequences. Current safety requirements for thermal reactors in the UK and particular requirements in the design of the Heysham II and Torness reactors are discussed

  17. Design features of a full-scale high-level waste vitrification system

    International Nuclear Information System (INIS)

    Siemens, D.H.; Bonner, W.F.

    1976-08-01

    A system has been designed and is currently under construction for vitrification of commercial high-level waste. The process consists of a spray calciner coupled to an in-can melter. Due to the high radiation levels expected, this equipment is designed for totally remote operation and maintenance. The in-cell arrangement of this equipment has been developed cooperatively with a nuclear fuel reprocessor. The system will be demonstrated both full scale with nonradioactive simulated waste and pilot scale with actual high-level waste

  18. Successful Bullying Prevention Programs: Influence of Research Design, Implementation Features, and Program Components

    Directory of Open Access Journals (Sweden)

    Bryanna Hahn Fox

    2012-12-01

    Full Text Available Bullying prevention programs have been shown to be generally effective in reducing bullying and victimization. However, the effects are relatively small in randomized experiments and greater in quasi-experimental and age-cohort designs. Programs that are more intensive and of longer duration (for both children and teachers are more effective, as are programs containing more components. Several program components are associated with large effect sizes, including parent training or meetings and teacher training. These results should inform the design and evaluation of anti-bullying programs in the future, and a system ofaccreditation of effective programs.

  19. Mechanical Design Features of the KALIMER-600 Sodium-Cooled Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jae Han; Park, Chang Gyu; Kim, Jong Bum [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    2005-07-01

    KALIMER-600 is a sodium cooled reactor with a fast spectrum neutron reactor core. The NSSS design has three heat transport systems of a PHTS (Primary Heat Transport System), a IHTS (Intermediate Heat Transport System) and a SGS (Steam Generation System). PHTS is a pool type and has a large amount of sodium in the pool. The mechanical design targets are maintaining the enough structural integrity for a seismic load of SSE 0.3g and the thermal and mechanical loads by the high temperature environments and an economical competitiveness when compared with other reactor types.

  20. Mechanical Design Features of the KALIMER-600 Sodium-Cooled Reactor

    International Nuclear Information System (INIS)

    Lee, Jae Han; Park, Chang Gyu; Kim, Jong Bum

    2005-01-01

    KALIMER-600 is a sodium cooled reactor with a fast spectrum neutron reactor core. The NSSS design has three heat transport systems of a PHTS (Primary Heat Transport System), a IHTS (Intermediate Heat Transport System) and a SGS (Steam Generation System). PHTS is a pool type and has a large amount of sodium in the pool. The mechanical design targets are maintaining the enough structural integrity for a seismic load of SSE 0.3g and the thermal and mechanical loads by the high temperature environments and an economical competitiveness when compared with other reactor types

  1. Design features in Korean next generation reactor focused on performance and economic viability

    International Nuclear Information System (INIS)

    Lee, J.S.; Chung, M.S.; Na, J.H.; Kim, M.C.; Choi, Y.S.

    2001-01-01

    As of the end of Dec. 1999, Korea's total nuclear power capacity reached 13,716 MWe with 16 units in operation and 4 units under construction. In addition, as part of the national long-term R and D programme launched in 1992, the Korean Next Generation Reactor (KNGR) is being developed to meet the electricity demands in the years to come and is expected to be safer and more economically competitive than any other conventional electric power sources in Korea. The KNGR project has successfully completed its second phase and is now on the third phase. In Phase III of the KNGR design development project, KNGR aims at reinforcing the economic competitiveness while maintaining safety goals. To achieve these objectives, the design options studied and the design requirements set up in the first phase are pursued while the second phase are being reviewed. This paper summarizes such efforts for design improvement in terms of performance and economic viability along with the status of nuclear power generation in Korea, focusing on KNGR currently. (author)

  2. Essential Features of Serious Games Design in Higher Education: Linking Learning Attributes to Game Mechanics

    Science.gov (United States)

    Lameras, Petros; Arnab, Sylvester; Dunwell, Ian; Stewart, Craig; Clarke, Samantha; Petridis, Panagiotis

    2017-01-01

    This paper consolidates evidence and material from a range of specialist and disciplinary fields to provide an evidence-based review and synthesis on the design and use of serious games in higher education. Search terms identified 165 papers reporting conceptual and empirical evidence on how learning attributes and game mechanics may be planned,…

  3. Book featuring Grand Egyptian Museum design proposals by Ahmed Ali published

    OpenAIRE

    Chadwick, Heather Riley

    2009-01-01

    "Silence, Darkness and Light," a new book by Ahmed K. Ali, adjunct professor of architecture in the School of Architecture + Design and program leader for study abroad in Egypt for Virginia Tech's College of Architecture and Urban Studies, has been published by VDM Verlag in Saarbrucken, Germany.

  4. The Key Lake project

    International Nuclear Information System (INIS)

    1991-01-01

    Key Lake is located in the Athabasca sand stone basin, 640 kilometers north of Saskatoon, Saskatchewan, Canada. The three sources of ore at Key Lake contain 70 100 tonnes of uranium. Features of the Key Lake Project were described under the key headings: work force, mining, mill process, tailings storage, permanent camp, environmental features, worker health and safety, and economic benefits. Appendices covering the historical background, construction projects, comparisons of western world mines, mining statistics, Northern Saskatchewan surface lease, and Key Lake development and regulatory agencies were included

  5. The Specific Features of design and process engineering in branch of industrial enterprise

    Science.gov (United States)

    Sosedko, V. V.; Yanishevskaya, A. G.

    2017-06-01

    Production output of industrial enterprise is organized in debugged working mechanisms at each stage of product’s life cycle from initial design documentation to product and finishing it with utilization. The topic of article is mathematical model of the system design and process engineering in branch of the industrial enterprise, statistical processing of estimated implementation results of developed mathematical model in branch, and demonstration of advantages at application at this enterprise. During the creation of model a data flow about driving of information, orders, details and modules in branch of enterprise groups of divisions were classified. Proceeding from the analysis of divisions activity, a data flow, details and documents the state graph of design and process engineering was constructed, transitions were described and coefficients are appropriated. To each condition of system of the constructed state graph the corresponding limiting state probabilities were defined, and also Kolmogorov’s equations are worked out. When integration of sets of equations of Kolmogorov the state probability of system activity the specified divisions and production as function of time in each instant is defined. On the basis of developed mathematical model of uniform system of designing and process engineering and manufacture, and a state graph by authors statistical processing the application of mathematical model results was carried out, and also advantage at application at this enterprise is shown. Researches on studying of loading services probability of branch and third-party contractors (the orders received from branch within a month) were conducted. The developed mathematical model of system design and process engineering and manufacture can be applied to definition of activity state probability of divisions and manufacture as function of time in each instant that will allow to keep account of loading of performance of work in branches of the enterprise.

  6. FEATURES OF DESIGN OF TIED-ARCH BRIDGES WITH FLEXIBLE INCLINED SUSPENSION HANGERS

    Directory of Open Access Journals (Sweden)

    V. O. Samosvat

    2017-10-01

    Full Text Available Purpose. Investigation and analysis of the hanger arrangement and the structural stability of a Network arch bridge – a tied-arch bridge with inclined hangers that cross each other at least twice. It is also necessary to make a comparative analysis with other types of hanger arrangements. Methodology. The authors in their research investigated a large number of parameters to determine their influence in the force distribution in the arch. Eventually they determined optimal values for all parameters. These optimal values allowed developing a design guide that leads to optimal arch design. When solving this problem, the authors used three-dimensional finite element models and the objective was to determine the most suitable solution for a road bridge, with a span of 100 meters, consisting of two inclined steel arches, located on a road with two traffic lanes, subjected to medium traffic. The virtual prototype of the model is performed by finite element simulator Midas Civil. Findings. In this study, for the bridge deck, a concrete tie appears to be the best solution considering the structural behavior of network arches, but economic advantages caused by easier erection may lead to steel or a composite bridge deck as better alternatives. Design requirements and local conditions of each particular bridge project will decide the most economic deck design.Originality. To ensure passenger comfort and the stability and continuity of the track, deformations of bridges are constricted. A network arch is a stiff structure with small deflections and therefore suitable to comply with such demands even for high speed railway traffic.
A network arch bridge with a concrete tie usually saves more than half the steel required for tied arches with vertical hangers and concrete ties. Practical value. Following the study design advice given in this article leads to savings of about 60 % of structural steel compared with conventional tied arch bridges with

  7. Simultaneous inhibition of key growth pathways in melanoma cells and tumor regression by a designed bidentate constrained helical peptide.

    Science.gov (United States)

    Dhar, Amlanjyoti; Mallick, Shampa; Ghosh, Piya; Maiti, Atanu; Ahmed, Israr; Bhattacharya, Seemana; Mandal, Tapashi; Manna, Asit; Roy, Koushik; Singh, Sandeep; Nayak, Dipak Kumar; Wilder, Paul T; Markowitz, Joseph; Weber, David; Ghosh, Mrinal K; Chattopadhyay, Samit; Guha, Rajdeep; Konar, Aditya; Bandyopadhyay, Santu; Roy, Siddhartha

    2014-07-01

    Protein-protein interactions are part of a large number of signaling networks and potential targets for drug development. However, discovering molecules that can specifically inhibit such interactions is a major challenge. S100B, a calcium-regulated protein, plays a crucial role in the proliferation of melanoma cells through protein-protein interactions. In this article, we report the design and development of a bidentate conformationally constrained peptide against dimeric S100B based on a natural tight-binding peptide, TRTK-12. The helical conformation of the peptide was constrained by the substitution of α-amino isobutyric acid--an amino acid having high helical propensity--in positions which do not interact with S100B. A branched bidentate version of the peptide was bound to S100B tightly with a dissociation constant of 8 nM. When conjugated to a cell-penetrating peptide, it caused growth inhibition and rapid apoptosis in melanoma cells. The molecule exerts antiproliferative action through simultaneous inhibition of key growth pathways, including reactivation of wild-type p53 and inhibition of Akt and STAT3 phosphorylation. The apoptosis induced by the bidentate constrained helix is caused by direct migration of p53 to mitochondria. At moderate intravenous dose, the peptide completely inhibits melanoma growth in a mouse model without any significant observable toxicity. The specificity was shown by lack of ability of a double mutant peptide to cause tumor regression at the same dose level. The methodology described here for direct protein-protein interaction inhibition may be effective for rapid development of inhibitors against relatively weak protein-protein interactions for de novo drug development. © 2014 Wiley Periodicals, Inc.

  8. Toward Meaningful Manufacturing Variation Data in Design - Feature Based Description of Variation in Manufacturing Processes

    DEFF Research Database (Denmark)

    Eifler, Tobias; Boorla, Srinivasa Murthy; Howard, Thomas J.

    2016-01-01

    The need to mitigate the effects of manufacturing variation already in design is nowadays commonly acknowledged and has led to a wide use of predictive modeling techniques, tolerancing approaches, etc. in industry. The trustworthiness of corresponding variation analyses is, however, not ensured...... by the availability of sophisticated methods and tools alone, but does evidently also depend on the accuracy of the input information used. As existing approaches for the description of manufacturing variation focus however, almost exclusively, on monitoring and controlling production processes, there is frequently...... a lack of objective variation data in design. As a result, variation analyses and tolerancing activities rely on numerous assumptions made to fill the gaps of missing or incomplete data. To overcome this hidden subjectivity, a schema for a consistent and standardised description of manufacturing...

  9. Design features of a seven-cell high-gradient superconducting cavity

    International Nuclear Information System (INIS)

    Liska, D.J.; Ledford, J.; Black, S.; Spalek, G.; DiMarco, J.N.

    1992-01-01

    A cavity development program is in place at Los Alamos National Laboratory to evaluate structures that could be used to accelerate pions. The work is being guided by the conceptual design of PILAC, a high-gradient superconducting linac for raising the energy of rapidly decaying intense pion beams generated by Los Alamos Meson Physics Facility (LAMPF) to 1 GeV. The specification requires a cavity gradient of 12.5 MV/m at 805 MHz. The design of a seven-cell prototype cavity to achieve these high gradients has been completed by the Accelerator Technology division. The cavity is presently under procurement for high power testing a 2.0 K in 1993

  10. Linking fuel design features ampersand plant management to uranium, SWU savings

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    This article, contributed by Scott Garrett, Manager of Planning and Uranium Operations for Siemens Power Corporation in Bellevue, Washington, explores the impact of advances in fuel design and fuel management strategies on uranium utilization in the United States. Nuclear plant operators are deriving substantial benefits from these changes, including longer fuel cycle lengths, increased burnup, and added capacity - and experiencing cost savings in both uranium and enrichment services at the same time

  11. Salient design features of secondary containment structure of Narora Atomic Power Project

    International Nuclear Information System (INIS)

    Rahalkar, B.D.

    1975-01-01

    Design of the secondary containment structure for Narora Atomic Power Project is an improvement over the two earlier structures at of Rajasthan and Kalpakkam wherein Candu-type of reactors are involved. The major improvements envisaged are : to limit the leakage through the double containment envelope to 0.1% of volume of the building per day as against 0.1% per hour achieved for earlier stations; to separate heavy water atmosphere from that of light water for effective heavy water recovery; and better man-rem budgetting by limiting inner containment structure upto boiler room floor level and making boiler room area accessible during normal operation for servicing of light water system equipment. Narora Atomic Power Station is located in the Indo-Gangetic alluvial plains in seismically active zone IV. Comprehensive soil investigation, including dynamic properties of soil is required to be undertaken as the foundation level of the containment structure is 17 M below the ground level. The salient results of this investigation relevant to the foundations as well as type of foundation proposed are presented in brief. Double containment concept similar to that adopted for Kalpakkam station is provided for this station also. However, necessary changes in design to withstand large earthquake forces are required to be made. These design problems are discussed in brief. (author)

  12. Experimental and design experience with passive safety features of liquid metal reactors

    International Nuclear Information System (INIS)

    Lucoff, D.M.; Waltar, A.E.; Sackett, J.I.; Salvatores, M.; Aizawa, K.

    1992-10-01

    Liquid metal cooled reactors (LMRs) have already been demonstrated to be robust machines. Many reactor designers now believe that it is possible to include in this technology sufficient passive safety that LMRs would be able to survive loss of flow, loss of heat sink, and transient overpower events, even if the plant protective system fails completely and do so without damage to the core. Early whole-core testing in Rapsodie, EBR-II. and FFTF indicate such designs may be possible. The operational safety testing program in EBR-II is demonstrating benign response of the reactor to a full range of controls failures. But additional testing is needed if transient core structural response under major accident conditions is to be properly understood. The proposed international Phase IIB passive safety tests in FFTF, being designed with a particular emphasis on providing, data to understand core bowing extremes, and further tests planned in EBR-11 with processed IFR fuel should provide a substantial and unique database for validating the computer codes being used to simulate postulated accident conditions

  13. Conceptual design of wearpack with physiology detector feature based on wearable instrumentation

    Science.gov (United States)

    Sukirman, Melani; Laksono, Pringgo Widyo; Priadythama, Ilham; Susmartini, Susy; Suhardi, Bambang

    2017-11-01

    Every company in Indonesia is responsible for their worker health and safety condition as mentioned in UU No I year 1970. In manufacturing industries, there are many manual tasks dealing with high work load and risk, so that they require excellent concentration and physical condition. There is no ideal way to guarantee worker safety without a real time physiological monitoring. This paper reports our ongoing study in conceptual design development of worker's clothing which is equipped with a wearable instrumentation system. The system is designed to detect and measure body temperature and pulse in real time. Some electrical components such as, LCD (liquid crystal display), LEDs (light emitting diode), batteries, and physiological sensors were assembled. All components are controlled by a wearable on board controller. LEDs is used as alert which can indicate abnormal physical conditions. The LCD was added to provide more detail information. TMP 36 and XD-58C were selected as the physiological sensors. Finally, an Arduino Lilypad was chosen for the controller. This instrumentation system was verified by accurately detected and inform physiological condition of 3 subjects. Further we are going to attach the system to a worker's clothing which was specifically designed to simplify and comfortable usage.

  14. A-Well defined raw material specifications of product and its components, a key of successful new product design. A critical evaluation by case study

    OpenAIRE

    Vidyadhar Malhar Dandge; Heramb Vidyadhar Dandge

    2015-01-01

    New product design and development indeed needs long termvision for better product life and hence to have better product features the design team has to take into consideration various techno-commercial aspects todesign and develop most adequate new product. Normally in case of new product design all related activities are initiated by the team of technicians under the directive jointly given by top and marketing management of the concerned organization. Due to global competition ...

  15. SWR 1000: the main design features of the advanced boiling water reactor with passive safety systems

    International Nuclear Information System (INIS)

    Carsten, Pasler

    2007-01-01

    The SWR-1000 (1000 MW) is a boiling water reactor whose economic efficiency in comparison with large-capacity designs is achieved by deploying very simple passive safety equipment, simplified systems for plant operation, and a very simple plant configuration in which systems engineering is optimized and dependence on electrical and instrumentation and control systems is reduced. In addition, systems and components that require protection against natural and external man-made hazards are accommodated in such a way that as few buildings as possible have to be designed to withstand the loads from such events. The fuel assemblies have been enlarged from a 10*10 rod array to a 12*12 array. This reduces the total number of fuel assemblies in the core and thus also the number of control rods and control rod drives, as well as in-core neutron flux monitors. The design owes its competitiveness to the fact that investment costs, maintenance costs and fuel cycle costs are all lower. In addition, refueling outages are shorter, thanks to the reduced scope of outage activities. The larger fuel assemblies have been extensively and successfully tested, as have all of the other new components and systems incorporated into the plant design. As in existing plants, the forced coolant circulation method is deployed, ensuring problem-free startup, and enabling plant operators to adjust power rapidly in the high power range (70%-100%) without moving the control rods, as well as allowing spectral-shift and stretch-out operation. The plant safety concept is based on a combination of passive safety systems and a reduced number of active safety systems. All postulated accidents can be controlled using passive systems alone. Control of a postulated core melt accident is assured with considerable safety margins thanks to passive flooding of the containment for in-vessel melt retention. The SWR-1000 is compliant with international nuclear codes and standards, and is also designed to withstand

  16. Immunological Features of Respiratory Syncytial Virus-Caused Pneumonia—Implications for Vaccine Design

    Directory of Open Access Journals (Sweden)

    Emma Rey-Jurado

    2017-03-01

    Full Text Available The human respiratory syncytial virus (hRSV is the causative agent for high rates of hospitalizations due to viral bronchiolitis and pneumonia worldwide. Such a disease is characterized by an infection of epithelial cells of the distal airways that leads to inflammation and subsequently to respiratory failure. Upon infection, different pattern recognition receptors recognize the virus and trigger the innate immune response against the hRSV. Further, T cell immunity plays an important role for virus clearance. Based on animal studies, it is thought that the host immune response to hRSV is based on a biased T helper (Th-2 and Th17 T cell responses with the recruitment of T cells, neutrophils and eosinophils to the lung, causing inflammation and tissue damage. In contrast, human immunity against RSV has been shown to be more complex with no definitive T cell polarization profile. Nowadays, only a humanized monoclonal antibody, known as palivizumab, is available to protect against hRSV infection in high-risk infants. However, such treatment involves several injections at a significantly high cost. For these reasons, intense research has been focused on finding novel vaccines or therapies to prevent hRSV infection in the population. Here, we comprehensively review the recent literature relative to the immunological features during hRSV infection, as well as the new insights into preventing the disease caused by this virus.

  17. A Novel Approach in Quantifying the Effect of Urban Design Features on Local-Scale Air Pollution in Central Urban Areas.

    Science.gov (United States)

    Miskell, Georgia; Salmond, Jennifer; Longley, Ian; Dirks, Kim N

    2015-08-04

    Differences in urban design features may affect emission and dispersion patterns of air pollution at local-scales within cities. However, the complexity of urban forms, interdependence of variables, and temporal and spatial variability of processes make it difficult to quantify determinants of local-scale air pollution. This paper uses a combination of dense measurements and a novel approach to land-use regression (LUR) modeling to identify key controls on concentrations of ambient nitrogen dioxide (NO2) at a local-scale within a central business district (CBD). Sixty-two locations were measured over 44 days in Auckland, New Zealand at high density (study area 0.15 km(2)). A local-scale LUR model was developed, with seven variables identified as determinants based on standard model criteria. A novel method for improving standard LUR design was developed using two independent data sets (at local and "city" scales) to generate improved accuracy in predictions and greater confidence in results. This revised multiscale LUR model identified three urban design variables (intersection, proximity to a bus stop, and street width) as having the more significant determination on local-scale air quality, and had improved adaptability between data sets.

  18. Designing a Web Spam Classifier Based on Feature Fusion in the Layered Multi-Population Genetic Programming Framework

    Directory of Open Access Journals (Sweden)

    Amir Hosein KEYHANIPOUR

    2013-11-01

    Full Text Available Nowadays, Web spam pages are a critical challenge for Web retrieval systems which have drastic influence on the performance of such systems. Although these systems try to combat the impact of spam pages on their final results list, spammers increasingly use more sophisticated techniques to increase the number of views for their intended pages in order to have more commercial success. This paper employs the recently proposed Layered Multi-population Genetic Programming model for Web spam detection task as well application of correlation coefficient analysis for feature space reduction. Based on our tentative results, the designed classifier, which is based on a combination of easy to compute features, has a very reasonable performance in comparison with similar methods.

  19. Five features of value-based insurance design plans were associated with higher rates of medication adherence.

    Science.gov (United States)

    Choudhry, Niteesh K; Fischer, Michael A; Smith, Benjamin F; Brill, Gregory; Girdish, Charmaine; Matlin, Olga S; Brennan, Troyen A; Avorn, Jerry; Shrank, William H

    2014-03-01

    Value-based insurance design (VBID) plans selectively lower cost sharing to increase medication adherence. Existing plans have been structured in a variety of ways, and these variations could influence the effectiveness of VBID plans. We evaluated seventy-six plans introduced by a large pharmacy benefit manager during 2007-10. We found that after we adjusted for the other features and baseline trends, VBID plans that were more generous, targeted high-risk patients, offered wellness programs, did not offer disease management programs, and made the benefit available only for medication ordered by mail had a significantly greater impact on adherence than plans without these features. The effects were as large as 4-5 percentage points. These findings can provide guidance for the structure of future VBID plans.

  20. Cost reduction and safety design features of new nuclear power plants in India. Annex 13

    International Nuclear Information System (INIS)

    Sharma, V.K.

    2002-01-01

    Indian Nuclear Power Programme is designed to exploit limited reserves of uranium and extensive resource of thorium. Pressurised heavy water reactors are found most suitable and form the main stay of the first stage of the programme. Thorium utilisation is achieved in the second and third stages. Today India has total installed capacity of 2720 MWe of PHWRs which are operating with high plant load factors of over 80%. Rich experience of construction and operation of over 150 reactor years is being utilised in effecting cost reduction and safety improvements. Standardisation and reduction in gestation period by preproject activities, advance procurement and work packages of engineer, procure, construct and commission are some of the techniques being adopted for cost reduction in the new projects. But the cost of safety is rising. Design basis event of double ended guillotine rupture of primary pressure boundary needs a relook based on current knowledge of material behaviour. This event appears improbable. Similarly some of the safety related systems like closed loop cooling water operating at low temperature and pressure, and low usage factors may be designed as per standard codes without invoking special nuclear requirements. The paper will address these issues and highlight the possible areas for cost reduction both in operating and safety systems. Modern construction and project management techniques are being employed. Gestation period of 5 years and cost of less than US $1400 per KWe are the present targets. In Indian environment nuclear power is found to be competitive with thermal power plants at distances of about 800 Kms from the coal mines. (author)

  1. Analysis of mobile phone design features affecting radiofrequency power absorbed in a human head phantom.

    Science.gov (United States)

    Kuehn, Sven; Kelsh, Michael A; Kuster, Niels; Sheppard, Asher R; Shum, Mona

    2013-09-01

    The US FCC mandates the testing of all mobile phones to demonstrate compliance with the rule requiring that the peak spatial SAR does not exceed the limit of 1.6 W/kg averaged over any 1 g of tissue. These test data, measured in phantoms with mobile phones operating at maximum antenna input power, permitted us to evaluate the variation in SARs across mobile phone design factors such as shape and antenna design, communication technology, and test date (over a 7-year period). Descriptive statistical summaries calculated for 850 MHz and 1900 MHz phones and ANOVA were used to evaluate the influence of the foregoing factors on SARs. Service technology accounted for the greatest variability in compliance test SARs that ranged from AMPS (highest) to CDMA, iDEN, TDMA, and GSM (lowest). However, the dominant factor for SARs during use is the time-averaged antenna input power, which may be much less than the maximum power used in testing. This factor is largely defined by the communication system; e.g., the GSM phone average output can be higher than CDMA by a factor of 100. Phone shape, antenna type, and orientation of a phone were found to be significant but only on the order of up to a factor of 2 (3 dB). The SAR in the tilt position was significantly smaller than for touch. The side of the head did not affect SAR levels significantly. Among the remaining factors, external antennae produced greater SARs than internal ones, and brick and clamshell phones produced greater SARs than slide phones. Assuming phone design and usage patterns do not change significantly over time, we have developed a normalization procedure and formula that permits reliable prediction of the relative SAR between various communication systems. This approach can be applied to improve exposure assessment in epidemiological research. Copyright © 2013 Wiley Periodicals, Inc.

  2. Proposal for a market design featuring privatised capacity coverage; Vorschlag fuer ein Marktdesign der privatisierten Leistungsversorgung

    Energy Technology Data Exchange (ETDEWEB)

    Cremer, Clemens [EnBW Trading GmbH, Karlsruhe (Germany)

    2013-01-15

    An intensive discussion is currently waging in Germany about the necessity and possible designs of capacity mechanisms. Price-inelastic demand increases the risk of market failure, as does the policy of managing capacity coverage as if it were a public good. By privatising capacity management it becomes possible to solve problems of security of supply by market means. This involves charging the supplier with the ultimate responsibility of providing its customers with just the capacity they need at any given moment in time.

  3. Identifying heavy-ion-beam fusion design and system features with high economic leverage

    International Nuclear Information System (INIS)

    Meier, W.R.; Hogan, W.J.

    1985-01-01

    We have conducted parametric economic studies for heavy-ion-beam fusion electric power plants. We examined the effects on the cost of electricity of several design parameters: maximum achievable chamber pulse rate, driver cost, target gain, and electric conversion efficiency, and net electric power. We found with reasonable assumptions on driver cost, target gain, and electric conversion efficiency, a 2 to 3 GWe heavy-ion-beam fusion power plant, with a chamber pulse rate of 5 to 10 Hz, can be competitive with nuclear and coal power plants

  4. Design features and operational characteristics of the PEP beam-transport and injection system

    International Nuclear Information System (INIS)

    Peterson, J.M.; Brown, K.L.; Truher, J.B.

    1981-03-01

    The PEP beam-transport system was designed to transmit 4-to-15 GeV electron and positron beams from the SLAC linac within a +- 0.8% momentum band, to have flexible tuning of the betatron and off-momentum functions for matching into the PEP storage ring, and to have convenient operating characteristics. The transport lines were brought into operation quickly and have operated well. Electron injection has been consistent and efficient and relatively easy to accomplish. Positron injection also has been satisfactory but is variable and more sensitive to ring conditions

  5. Design of a New 4-DOF Haptic Master Featuring Magnetorheological Fluid

    Directory of Open Access Journals (Sweden)

    Byung-Keun Song

    2014-08-01

    Full Text Available This work presents a novel 4-degree-of-freedom (4-DOF haptic master using magnetorheological (MR fluid which is applicable to a robot-assisted minimally invasive surgery (RMIS system. By using MR fluid, the proposed haptic device can easily generate bidirectional repulsive torque along the directions of the required motions. The proposed master consists of two actuators: an MR bidirectional clutch associated with a planetary gear system and an MR clutch with a bevel gear system. After demonstrating the configuration, the torque models of MR actuators are mathematically derived based on the field-dependent Bingham model. An optimal design that accounts for spatial-limitation and the desired torque constraint is then undertaken. An optimization procedure based on finite element analysis is proposed to determine optimal geometric dimensions. Based on the design procedure, MR haptic master with the optimal parameters has been manufactured. In order to demonstrate the practical feasibility of the proposed haptic master, the field-dependent generating repulsive force is measured. In addition, a proportional-integral-derivative (PID controller is empirically implemented to accomplish the desired torque trajectories. It has been shown that the proposed haptic master can track the desired torque trajectory without a significant error.

  6. Status review of large fast reactor core designs and their dynamics related features

    International Nuclear Information System (INIS)

    Spenke, H.; Kiefhaber, E.

    1982-01-01

    Since several years conventional and unconventional concepts of large fast reactor cores have been investigated in the Federal Republic of Germany at INTERATOM and Kernforschungszentrum Karlsruhe. The work was performed jointly with Belgonucleaire (Belgium). Basically, the studies were aimed at the determination of the performance potential of different core concepts for large fast reactors. Thus the following points were considered: power distribution, neutron fluence and residence time, doubling time, uranium ore consumption, dynamics and safety related features, economics, cooling strategy, core element bowing behaviour. In this paper, the state of the analysis will be presented with emphasis on those points relevant for this meeting. However, we have to make clear, that dynamic and accident studies are still under way and that we are not yet able to cover these aspects in a quantitative manner. This is due to the fact, that the efforts in the DeBeNe-countries have been concentrated on the work necessary for being granted the different licenses for SNR 300, fast breeder prototype reactor near Kalkar. As we expect to obtain these important licenses at the beginning of 1982, an increased man power can be devoted to studies of dynamic and safety problems of large fast cores from that time on. These studies have to fit into the planning recently announced by the utility ESK who will be ordering SNR 2, the first demonstration breeder reactor of Germany, Belgium, Netherlands and France. The planning calls for concept decisions in 1983, leading to an engineering contract for SNR 2 in 1983/1984. Accordingly we shall have to complete and evaluate the ongoing core concept Investigations till 1983 resulting in a subsequent final choice

  7. A preclinical orthotopic model for glioblastoma recapitulates key features of human tumors and demonstrates sensitivity to a combination of MEK and PI3K pathway inhibitors.

    Science.gov (United States)

    El Meskini, Rajaa; Iacovelli, Anthony J; Kulaga, Alan; Gumprecht, Michelle; Martin, Philip L; Baran, Maureen; Householder, Deborah B; Van Dyke, Terry; Weaver Ohler, Zoë

    2015-01-01

    Current therapies for glioblastoma multiforme (GBM), the highest grade malignant brain tumor, are mostly ineffective, and better preclinical model systems are needed to increase the successful translation of drug discovery efforts into the clinic. Previous work describes a genetically engineered mouse (GEM) model that contains perturbations in the most frequently dysregulated networks in GBM (driven by RB, KRAS and/or PI3K signaling and PTEN) that induce development of Grade IV astrocytoma with properties of the human disease. Here, we developed and characterized an orthotopic mouse model derived from the GEM that retains the features of the GEM model in an immunocompetent background; however, this model is also tractable and efficient for preclinical evaluation of candidate therapeutic regimens. Orthotopic brain tumors are highly proliferative, invasive and vascular, and express histology markers characteristic of human GBM. Primary tumor cells were examined for sensitivity to chemotherapeutics and targeted drugs. PI3K and MAPK pathway inhibitors, when used as single agents, inhibited cell proliferation but did not result in significant apoptosis. However, in combination, these inhibitors resulted in a substantial increase in cell death. Moreover, these findings translated into the in vivo orthotopic model: PI3K or MAPK inhibitor treatment regimens resulted in incomplete pathway suppression and feedback loops, whereas dual treatment delayed tumor growth through increased apoptosis and decreased tumor cell proliferation. Analysis of downstream pathway components revealed a cooperative effect on target downregulation. These concordant results, together with the morphologic similarities to the human GBM disease characteristics of the model, validate it as a new platform for the evaluation of GBM treatment. © 2015. Published by The Company of Biologists Ltd.

  8. A preclinical orthotopic model for glioblastoma recapitulates key features of human tumors and demonstrates sensitivity to a combination of MEK and PI3K pathway inhibitors

    Directory of Open Access Journals (Sweden)

    Rajaa El Meskini

    2015-01-01

    Full Text Available Current therapies for glioblastoma multiforme (GBM, the highest grade malignant brain tumor, are mostly ineffective, and better preclinical model systems are needed to increase the successful translation of drug discovery efforts into the clinic. Previous work describes a genetically engineered mouse (GEM model that contains perturbations in the most frequently dysregulated networks in GBM (driven by RB, KRAS and/or PI3K signaling and PTEN that induce development of Grade IV astrocytoma with properties of the human disease. Here, we developed and characterized an orthotopic mouse model derived from the GEM that retains the features of the GEM model in an immunocompetent background; however, this model is also tractable and efficient for preclinical evaluation of candidate therapeutic regimens. Orthotopic brain tumors are highly proliferative, invasive and vascular, and express histology markers characteristic of human GBM. Primary tumor cells were examined for sensitivity to chemotherapeutics and targeted drugs. PI3K and MAPK pathway inhibitors, when used as single agents, inhibited cell proliferation but did not result in significant apoptosis. However, in combination, these inhibitors resulted in a substantial increase in cell death. Moreover, these findings translated into the in vivo orthotopic model: PI3K or MAPK inhibitor treatment regimens resulted in incomplete pathway suppression and feedback loops, whereas dual treatment delayed tumor growth through increased apoptosis and decreased tumor cell proliferation. Analysis of downstream pathway components revealed a cooperative effect on target downregulation. These concordant results, together with the morphologic similarities to the human GBM disease characteristics of the model, validate it as a new platform for the evaluation of GBM treatment.

  9. Identifying Key Features, Cutting Edge Cloud Resources, and Artificial Intelligence Tools to Achieve User-Friendly Water Science in the Cloud

    Science.gov (United States)

    Pierce, S. A.

    2017-12-01

    Decision making for groundwater systems is becoming increasingly important, as shifting water demands increasingly impact aquifers. As buffer systems, aquifers provide room for resilient responses and augment the actual timeframe for hydrological response. Yet the pace impacts, climate shifts, and degradation of water resources is accelerating. To meet these new drivers, groundwater science is transitioning toward the emerging field of Integrated Water Resources Management, or IWRM. IWRM incorporates a broad array of dimensions, methods, and tools to address problems that tend to be complex. Computational tools and accessible cyberinfrastructure (CI) are needed to cross the chasm between science and society. Fortunately cloud computing environments, such as the new Jetstream system, are evolving rapidly. While still targeting scientific user groups systems such as, Jetstream, offer configurable cyberinfrastructure to enable interactive computing and data analysis resources on demand. The web-based interfaces allow researchers to rapidly customize virtual machines, modify computing architecture and increase the usability and access for broader audiences to advanced compute environments. The result enables dexterous configurations and opening up opportunities for IWRM modelers to expand the reach of analyses, number of case studies, and quality of engagement with stakeholders and decision makers. The acute need to identify improved IWRM solutions paired with advanced computational resources refocuses the attention of IWRM researchers on applications, workflows, and intelligent systems that are capable of accelerating progress. IWRM must address key drivers of community concern, implement transdisciplinary methodologies, adapt and apply decision support tools in order to effectively support decisions about groundwater resource management. This presentation will provide an overview of advanced computing services in the cloud using integrated groundwater management case

  10. Silver nanoparticles as a key feature of a plasma polymer composite layer in mitigation of charge injection into polyethylene under dc stress

    International Nuclear Information System (INIS)

    Milliere, L; Makasheva, K; Laurent, C; Despax, B; Boudou, L; Teyssedre, G

    2016-01-01

    The aim of this work is to limit charge injection from a semi-conducting electrode into low density polyethylene (LDPE) under dc field by tailoring the polymer surface using a silver nanoparticles-containing layer. The layer is composed of a plane of silver nanoparticles embedded in a semi-insulating organosilicon matrix deposited on the polyethylene surface by a plasma process. Size, density and surface coverage of the nanoparticles are controlled through the plasma process. Space charge distribution in 300 μm thick LDPE samples is measured by the pulsed-electroacoustic technique following a short term (step-wise voltage increase up to 50 kV mm −1 , 20 min in duration each, followed by a polarity inversion) and a longer term (up to 12 h under 40 kV mm −1 ) protocols for voltage application. A comparative study of space charge distribution between a reference polyethylene sample and the tailored samples is presented. It is shown that the barrier effect depends on the size distribution and the surface area covered by the nanoparticles: 15 nm (average size) silver nanoparticles with a high surface density but still not percolating form an efficient barrier layer that suppress charge injection. It is worthy to note that charge injection is detected for samples tailored with (i) percolating nanoparticles embedded in organosilicon layer; (ii) with organosilicon layer only, without nanoparticles and (iii) with smaller size silver particles (<10 nm) embedded in organosilicon layer. The amount of injected charges in the tailored samples increases gradually in the samples ranking given above. The mechanism of charge injection mitigation is discussed on the basis of complementary experiments carried out on the nanocomposite layer such as surface potential measurements. The ability of silver clusters to stabilize electrical charges close to the electrode thereby counterbalancing the applied field appears to be a key factor in explaining the charge injection

  11. Design features of a reverse osmosis demonstration plant for treatment of low level radioactive waste

    International Nuclear Information System (INIS)

    Shekhar, P.; Sudesh Nath; Gandhi, P.M.; Mishra, S.D.

    1994-01-01

    Reverse osmosis, a novel process in the field of nuclear waste management, is under evaluation globally. Its application is basically considered for the treatment of low level waste; yet references are found for its possible use to treat specific intermediate level waste streams, if segregated at source. The process of reverse osmosis (RO) is proposed for use in conjunction with other conventional processes like chemical treatment, ion exchange and evaporation. Flow sheets have been developed wherein RO can come as a replacement of one of these processes or is used as a pre or post treatment stage. The emphasis is on reducing the secondary wastes so as to realize an optimum levelised cost of treatment. This paper outlines the design basis for an RO plant for treating low level radioactive wastes based on the studies carried out on laboratory as well as bench scale. (author)

  12. Design features of a reverse osmosis demonstration plant for treatment of low level radioactive waste

    Energy Technology Data Exchange (ETDEWEB)

    Shekhar, P; Nath, Sudesh; Gandhi, P M; Mishra, S D [Waste Management Projects Division, Bhabha Atomic Research Centre, Mumbai (India)

    1994-06-01

    Reverse osmosis, a novel process in the field of nuclear waste management, is under evaluation globally. Its application is basically considered for the treatment of low level waste; yet references are found for its possible use to treat specific intermediate level waste streams, if segregated at source. The process of reverse osmosis (RO) is proposed for use in conjunction with other conventional processes like chemical treatment, ion exchange and evaporation. Flow sheets have been developed wherein RO can come as a replacement of one of these processes or is used as a pre or post treatment stage. The emphasis is on reducing the secondary wastes so as to realize an optimum levelised cost of treatment. This paper outlines the design basis for an RO plant for treating low level radioactive wastes based on the studies carried out on laboratory as well as bench scale. (author). 3 figs., 3 tabs.

  13. Design features of the solenoid magnets for the central cell of the MFTF-B

    International Nuclear Information System (INIS)

    Wohlwend, J.W.; Tatro, R.E.; Ring, D.S.

    1981-01-01

    The 14 superconducting solenoid magnets which form the central cell of the MFTF-B are being designed and fabricated by General Dynamics for the Lawrence Livermore National Laboratory. Each solenoid coil has a mean diameter of five meters and contains 600 turns of a proven conductor type. Structural loading resulting from credible fault events, cooldown and warmup requirements, and manufacturing processes consistent with other MFTF-B magnets have been considered in the selection of 304 LN as the structural material for the magnet. The solenoid magnets are connected by 24 intercoil beams and 20 solid struts which resist the longitudinal seismic and electromagnetic attractive forces and by 24 hanger/side supports which react magnet dead weight and seismic loads. A modular arrangement of two solenoid coils within a vacuum vessel segment allow for sequential checkout and installation

  14. Genetically engineered rat gliomas: PDGF-driven tumor initiation and progression in tv-a transgenic rats recreate key features of human brain cancer.

    Directory of Open Access Journals (Sweden)

    Nina P Connolly

    Full Text Available Previously rodent preclinical research in gliomas frequently involved implantation of cell lines such as C6 and 9L into the rat brain. More recently, mouse models have taken over, the genetic manipulability of the mouse allowing the creation of genetically accurate models outweighed the disadvantage of its smaller brain size that limited time allowed for tumor progression. Here we illustrate a method that allows glioma formation in the rat using the replication competent avian-like sarcoma (RCAS virus / tumor virus receptor-A (tv-a transgenic system of post-natal cell type-specific gene transfer. The RCAS/tv-a model has emerged as a particularly versatile and accurate modeling technology by enabling spatial, temporal, and cell type-specific control of individual gene transformations and providing de novo formed glial tumors with distinct molecular subtypes mirroring human GBM. Nestin promoter-driven tv-a (Ntv-a transgenic Sprague-Dawley rat founder lines were created and RCAS PDGFA and p53 shRNA constructs were used to initiate intracranial brain tumor formation. Tumor formation and progression were confirmed and visualized by magnetic resonance imaging (MRI and spectroscopy. The tumors were analyzed using histopathological and immunofluorescent techniques. All experimental animals developed large, heterogeneous brain tumors that closely resembled human GBM. Median survival was 92 days from tumor initiation and 62 days from the first point of tumor visualization on MRI. Each tumor-bearing animal showed time dependent evidence of malignant progression to high-grade glioma by MRI and neurological examination. Post-mortem tumor analysis demonstrated the presence of several key characteristics of human GBM, including high levels of tumor cell proliferation, pseudopalisading necrosis, microvascular proliferation, invasion of tumor cells into surrounding tissues, peri-tumoral reactive astrogliosis, lymphocyte infiltration, presence of numerous tumor

  15. Design of the control room of the N4-type PWR: main features and feedback operating experience

    International Nuclear Information System (INIS)

    Peyrouton, J.M.; Guillas, J.; Nougaret, Ch.

    2004-01-01

    This article presents the design, specificities and innovating features of the control room of the N4-type PWR. A brief description of control rooms of previous 900 MW and 1300 MW -type PWR allows us to assess the change. The design of the first control room dates back to 1972, at that time 2 considerations were taken into account: first the design has to be similar to that of control rooms for thermal plants because plant operators were satisfied with it and secondly the normal operating situation has to be privileged to the prejudice of accidental situations just as it was in a thermal plant. The turning point was the TMI accident that showed the weight of human factor in accidental situations in terms of pilot team, training, procedures and the ergonomics of the work station. The impact of TMI can be seen in the design of 1300 MW-type PWR. In the beginning of the eighties EDF decided to launch a study for a complete overhaul of the control room concept, the aim was to continue reducing the human factor risk and to provide a better quality of piloting the plant in any situation. The result is the control room of the N4-type PWR. Today the cumulated feedback experience of N4 control rooms represents more than 20 years over a wide range of situations from normal to incidental, a survey shows that the N4 design has fulfilled its aims. (A.C.)

  16. Design and operating features of the high-level waste vitrification system for the West Valley demonstration project

    International Nuclear Information System (INIS)

    Siemens, D.H.; Beary, M.M.; Barnes, S.M.; Berger, D.N.; Brouns, R.A.; Chapman, C.C.; Jones, R.M.; Peters, R.D.; Peterson, M.E.

    1986-03-01

    A liquid-fed joule-heated ceramic melter system is the reference process for immobilization of the high-level liquid waste in the US and several foreign countries. This system has been under development for over ten years at Pacific Northwest Laboratory and other national laboratories operated for the US Department of Energy. Pacific Northwest Laboratory contributed to this research through its Nuclear Waste Treatment Program and used applicable data to design and test melters and related systems using remote handling of simulated radioactive wastes. This report describes the equipment designed in support of the high-level waste vitrification program at West Valley, New York. Pacific Northwest Laboratory worked closely with West Valley Nuclear Services Company to design a liquid-fed ceramic melter, a liquid waste preparation and feed tank and pump, an off-gas treatment scrubber, and an enclosed turntable for positioning the waste canisters. Details of these designs are presented including the rationale for the design features and the alternatives considered

  17. Evidence-Based Design Features Improve Sleep Quality Among Psychiatric Inpatients.

    Science.gov (United States)

    Pyrke, Ryan J L; McKinnon, Margaret C; McNeely, Heather E; Ahern, Catherine; Langstaff, Karen L; Bieling, Peter J

    2017-10-01

    The primary aim of the present study was to compare sleep characteristics pre- and post-move into a state-of-the-art mental health facility, which offered private sleeping quarters. Significant evidence points toward sleep disruption among psychiatric inpatients. It is unclear, however, how environmental factors (e.g., dorm-style rooms) impact sleep quality in this population. To assess sleep quality, a novel objective technology, actigraphy, was used before and after a facility move. Subjective daily interviews were also administered, along with the Horne-Ostberg Morningness-Eveningness Questionnaire and the Pittsburgh Sleep Quality Index. Actigraphy revealed significant improvements in objective sleep quality following the facility move. Interestingly, subjective report of sleep quality did not correlate with the objective measures. Circadian sleep type appeared to play a role in influencing subjective attitudes toward sleep quality. Built environment has a significant effect on the sleep quality of psychiatric inpatients. Given well-documented disruptions in sleep quality present among psychiatric patients undergoing hospitalization, design elements like single patient bedrooms are highly desirable.

  18. User oriented design features of Korea Multi-purpose Research Reactor and its utilization plan

    International Nuclear Information System (INIS)

    Kim, Byungkoo; Jun, Byungjin

    1994-01-01

    Construction of a 30 MW class Korea Multi-purpose Research Reactor (KMRR) is near its completion and expected to reach initial criticality by the end of 1994 at KAERI Taejon site. As Korea will become one of developed countries during the lifetime of this reactor and many worldwide high performance research reactors of the first generation are reaching end of life, it is believed that KMRR will meet the increasing domestic needs to utilize high performance research reactor and its worldwide role will be important as well. In reactor design, effort has been focused on optimization which can satisfy various future utilization demands as much as possible with enhanced safety as a basic requirement. Light water cooled and heavy water reflected compact core using low enriched and high uranium loaded fuel, computer controlled operation, etc. are expected to provide truly multi-purpose user environments with stable high quality neutron flux. High level experimental facilities and equipment for reactor fuel and material test, various studies using neutron beam, radioisotope production, semiconductor doping, neutron activation analysis, etc., will be completed in parallel with the reactor or gradually depending on users' needs. When KMRR becomes fully operational, it will not only serve the domestic users but also be a valuable tool for a worldwide research community using a research reactor

  19. Design of Radioiodinated Pharmaceuticals: Structural Features Affecting Metabolic Stability towards in Vivo Deiodination

    Science.gov (United States)

    van der Born, Dion; Klaren, Peter H. M.; Boerman, Otto C.; Rutjes, Floris P. J. T.

    2017-01-01

    Radioiodinated pharmaceuticals are convenient tracers for clinical and research investigations because of the relatively long half‐lives of radioactive iodine isotopes (i.e., 123I, 124I, and 131I) and the ease of their chemical insertion. Their application in radionuclide imaging and therapy may, however, be hampered by poor in vivo stability of the C–I bond. After an overview of the use of iodine in biology and nuclear medicine, we present here a survey of the catabolic pathways for iodinated xenobiotics, including their biodistribution, accumulation, and biostability. We summarize successful rational improvements in the biostability and conclude with general guidelines for the design of stable radioiodinated pharmaceuticals. It appears to be necessary to consider the whole molecule, rather than the radioiodinated fragment alone. Iodine radionuclides are generally retained in vivo on sp2 carbon atoms in iodoarenes and iodovinyl moieties, but not in iodinated heterocycles or on sp3 carbon atoms. Iodoarene substituents also have an influence, with increased in vivo deiodination in the cases of iodophenols and iodoanilines, whereas methoxylation and difluorination improve biostability. PMID:28736501

  20. Identifying heavy-ion-beam fusion design and system features with high economic leverage

    International Nuclear Information System (INIS)

    Meier, W.R.; Hogan, W.J.

    1985-01-01

    In this article the authors consider a heavy-ion-beam (HIB) fusion power plant that consists of a driver, a target factory, and one or more power units. A power unit is defined as all the buildings and equipment needed to generate electric power, provided the target and beams are delivered to the reaction chamber. Because the maximum achievable pulse rate in a single chamber is limited, more than one reaction chamber may be required to achieve the desired output of a single power unit. They distinguish between multiple power units and multiple reaction chambers so that they can examine separately the effects of increasing the number of reaction chambers at a constant net power and of increasing the power level by driving more power units with a single driver. The authors conducted studies to investigate the effects on the cost of electricity (COE) of variations in several design parameters. In particular, they examined the effects of maximum achievable chamber pulse rate, driver cost, target gain, electric conversion efficiency, and net electric power. They found that with a combination of improvements over their base case, HIB fusion can be economically competitive with present and future power sources

  1. Design features of the A-cell and transition coils of MFTF-B

    International Nuclear Information System (INIS)

    Tatro, R.E.; Wohlwend, J.W.; Ring, D.S.

    1981-01-01

    The MFTF-B transition coil and A-cell magnet designs use variations of the copper-stabilized NbTi conductor developed by LLNL for the MFTF Yin-Yang magnets. This conductor will be wound on the one inch thick (12.7 mm) stainless steel coil forms using a two-axis winding machine similar to the existing LLNL Yin-Yang winding machine. After winding, covers will be placed over the coil and welded to the coil form to form a helium-tight jacket around the conductor. These jacketed coils are then enclosed in thick structural cases that react the large Lorentz forces on the magnets. The space between the coil jacket and case will be filled by a stainless steel bladder that will be injected with urethane. The injection bladder will provide cooling passages during cooldown as well as transmitting the Lorentz forces between the jacket and the case. The large self-equilibrating lobe-spreading forces on the magnets (29.10 6 lb, 127.0 MN) for the A-cell are reacted primarily through the thick 304 LN case into the external superstructure. The net Lorentz forces and the inertial forces on the magnet are reacted through support systems into the LLNL vacuum vessel structure

  2. Cellphone with Dial and Call Feature Design Prototype for Children with Autism Spectrum Disorder (ASD

    Directory of Open Access Journals (Sweden)

    Bayu D. Wicaksono

    2012-09-01

    Full Text Available Autism Spectrum Disorder (ASD is a term that used to explain neurological problems which affect mind, perception and concentration. The unfortunate condition of children with ASD lead more difficult to do long-distance communication, not only because of the lack of device that can be used exclusively by children with ASD (the physical as well as its interface, but also because of their general habits tends to destroy something in this case is a commercial cellphone. Identification of ASD children’s habit will be conducted by distributing questionnaires and interviews of the parties which are well acquainted with their daily activities such as parents and school teachers. To validate the questionnaire, has also been conducted ethnographic video capture. The design of cell phone’s prototype and dial & call software/application interface in it is done using the Quality Function Deployment (QFD method as the results have been obtained from the collection of data on the habits of ASD children. In addition, there is also made a sound maker app.

  3. Towards mastering CRISPR-induced gene knock-in in plants: Survey of key features and focus on the model Physcomitrella patens.

    Science.gov (United States)

    Collonnier, Cécile; Guyon-Debast, Anouchka; Maclot, François; Mara, Kostlend; Charlot, Florence; Nogué, Fabien

    2017-05-15

    Beyond its predominant role in human and animal therapy, the CRISPR-Cas9 system has also become an essential tool for plant research and plant breeding. Agronomic applications rely on the mastery of gene inactivation and gene modification. However, if the knock-out of genes by non-homologous end-joining (NHEJ)-mediated repair of the targeted double-strand breaks (DSBs) induced by the CRISPR-Cas9 system is rather well mastered, the knock-in of genes by homology-driven repair or end-joining remains difficult to perform efficiently in higher plants. In this review, we describe the different approaches that can be tested to improve the efficiency of CRISPR-induced gene modification in plants, which include the use of optimal transformation and regeneration protocols, the design of appropriate guide RNAs and donor templates and the choice of nucleases and means of delivery. We also present what can be done to orient DNA repair pathways in the target cells, and we show how the moss Physcomitrella patens can be used as a model plant to better understand what DNA repair mechanisms are involved, and how this knowledge could eventually be used to define more performant strategies of CRISPR-induced gene knock-in. Copyright © 2017 Elsevier Inc. All rights reserved.

  4. Design Features of the Neutral Particle Diagnostic System for the ITER Tokamak

    Science.gov (United States)

    Petrov, S. Ya.; Afanasyev, V. I.; Melnik, A. D.; Mironov, M. I.; Navolotsky, A. S.; Nesenevich, V. G.; Petrov, M. P.; Chernyshev, F. V.; Kedrov, I. V.; Kuzmin, E. G.; Lyublin, B. V.; Kozlovski, S. S.; Mokeev, A. N.

    2017-12-01

    The control of the deuterium-tritium (DT) fuel isotopic ratio has to ensure the best performance of the ITER thermonuclear fusion reactor. The diagnostic system described in this paper allows the measurement of this ratio analyzing the hydrogen isotope fluxes (performing neutral particle analysis (NPA)). The development and supply of the NPA diagnostics for ITER was delegated to the Russian Federation. The diagnostics is being developed at the Ioffe Institute. The system consists of two analyzers, viz., LENPA (Low Energy Neutral Particle Analyzer) with 10-200 keV energy range and HENPA (High Energy Neutral Particle Analyzer) with 0.1-4.0MeV energy range. Simultaneous operation of both analyzers in different energy ranges enables researchers to measure the DT fuel ratio both in the central burning plasma (thermonuclear burn zone) and at the edge as well. When developing the diagnostic complex, it was necessary to account for the impact of several factors: high levels of neutron and gamma radiation, the direct vacuum connection to the ITER vessel, implying high tritium containment, strict requirements on reliability of all units and mechanisms, and the limited space available for accommodation of the diagnostic hardware at the ITER tokamak. The paper describes the design of the diagnostic complex and the engineering solutions that make it possible to conduct measurements under tokamak reactor conditions. The proposed engineering solutions provide a safe—with respect to thermal and mechanical loads—common vacuum channel for hydrogen isotope atoms to pass to the analyzers; ensure efficient shielding of the analyzers from the ITER stray magnetic field (up to 1 kG); provide the remote control of the NPA diagnostic complex, in particular, connection/disconnection of the NPA vacuum beamline from the ITER vessel; meet the ITER radiation safety requirements; and ensure measurements of the fuel isotopic ratio under high levels of neutron and gamma radiation.

  5. Feature of extradosed PC bridge and its design; Daihenshin keburu PC kyo no tokucho to sono sekkei

    Energy Technology Data Exchange (ETDEWEB)

    Komiya, M. [Japan Bridge and Structure Institute Inc., Tokyo (Japan)

    1997-03-31

    A PC bridge with the eccentricity of the external cable increased by protruding the deviated member to the outside of the beam for more effective use of the external cable is called a `PC bridge with tendons of large eccentricity.` The extradosed bridge of main beam/cable joint type is a PC bridge with the external cable arranged via a tower-shaped eccentric member provided at the intermediate support, and resembles morphologically a cable stayed bridge having a very low tower. There are two types of extradosed bridges, i.e. a type with concrete coated external cable (cable stayed slab bridge) and the other with non-coated external cable (external cable stayed bridge). Features, structural planning and designing of the general external cable stayed bridge are shown. The features are the possession of intermediate characteristics of those of the PC beam bridge and the PC cable stayed bridge from the viewpoints of structural property, workability, economic efficiency, and scenic property. Outline of the plan, selection of structural data, design of the external cable, and structural characteristics in the ultimate state are discussed. 19 refs., 18 figs., 15 tabs.

  6. State-of-the-art of wind turbine design codes: main features overview for cost-effective generation

    Energy Technology Data Exchange (ETDEWEB)

    Molenaar, D-P.; Dijkstra, S. [Delft University of Technology (Netherlands). Mechanical Engineering Systems and Control Group

    1999-07-01

    For successful large-scale application of wind energy, the price of electricity generated by wind turbines should decrease. Model-based control can be important since it has the potential to reduce fatigue loads, while simultaneously maintaining a desired amount of energy production. The controller synthesis, however, requires a mathematical model describing the most important dynamics of the complete wind turbine. In the wind energy community there is a wide variety in codes used to model a wind turbine's dynamic behaviour or to carry out design calculations. In this paper, the main features of the state-of-the-art wind turbine design codes have been investigated in order to judge the appropriateness of using one of these for the modeling, identification and control of flexible, variable speed wind turbines. It can be concluded that, although the sophistication of the design codes has increased enormously over the last two decades, they are, in general, not suitable for the design, and easy implementation of optimal operating strategies.

  7. Quantum key management

    Energy Technology Data Exchange (ETDEWEB)

    Hughes, Richard John; Thrasher, James Thomas; Nordholt, Jane Elizabeth

    2016-11-29

    Innovations for quantum key management harness quantum communications to form a cryptography system within a public key infrastructure framework. In example implementations, the quantum key management innovations combine quantum key distribution and a quantum identification protocol with a Merkle signature scheme (using Winternitz one-time digital signatures or other one-time digital signatures, and Merkle hash trees) to constitute a cryptography system. More generally, the quantum key management innovations combine quantum key distribution and a quantum identification protocol with a hash-based signature scheme. This provides a secure way to identify, authenticate, verify, and exchange secret cryptographic keys. Features of the quantum key management innovations further include secure enrollment of users with a registration authority, as well as credential checking and revocation with a certificate authority, where the registration authority and/or certificate authority can be part of the same system as a trusted authority for quantum key distribution.

  8. Designing healthy communities: creating evidence on metrics for built environment features associated with walkable neighbourhood activity centres.

    Science.gov (United States)

    Gunn, Lucy Dubrelle; Mavoa, Suzanne; Boulangé, Claire; Hooper, Paula; Kavanagh, Anne; Giles-Corti, Billie

    2017-12-04

    requirement that residents live within 1km of a local supermarket. Built environment features surrounding NACs must reach certain levels to encourage walking and deliver walkable communities. Research and metrics about the type and quantity of built environment features around both walking trip origins and destinations is needed to inform urban planning policies and urban design guidelines.

  9. Design and synthesis of polycyclic sulfones via Diels-Alder reaction and ring-rearrangement metathesis as key steps.

    Science.gov (United States)

    Kotha, Sambasivarao; Gunta, Rama

    2015-01-01

    Here, we describe a new and simple synthetic strategy to various polycyclic sulfones via Diels-Alder reaction and ring-rearrangement metathesis (RRM) as the key steps. This approach delivers tri- and tetracyclic sulfones with six (n = 1), seven (n = 2) or eight-membered (n = 3) fused-ring systems containing trans-ring junctions unlike the conventional all cis-ring junctions generally obtained during the RRM sequence. Interestingly the starting materials used are simple and commercially available.

  10. Optimal design of high damping force engine mount featuring MR valve structure with both annular and radial flow paths

    International Nuclear Information System (INIS)

    Nguyen, Q H; Choi, S B; Lee, Y S; Han, M S

    2013-01-01

    This paper focuses on the optimal design of a compact and high damping force engine mount featuring magnetorheological fluid (MRF). In the mount, a MR valve structure with both annular and radial flows is employed to generate a high damping force. First, the configuration and working principle of the proposed MR mount is introduced. The MRF flows in the mount are then analyzed and the governing equations of the MR mount are derived based on the Bingham plastic behavior of the MRF. An optimal design of the MR mount is then performed to find the optimal structure of the MR valve to generate a maximum damping force with certain design constraints. In addition, the gap size of MRF ducts is empirically chosen considering the ‘lockup’ problem of the mount at high frequency. Performance of the optimized MR mount is then evaluated based on finite element analysis and discussions on performance results of the optimized MR mount are given. The effectiveness of the proposed MR engine mount is demonstrated via computer simulation by presenting damping force and power consumption. (paper)

  11. Optimal design of high damping force engine mount featuring MR valve structure with both annular and radial flow paths

    Science.gov (United States)

    Nguyen, Q. H.; Choi, S. B.; Lee, Y. S.; Han, M. S.

    2013-11-01

    This paper focuses on the optimal design of a compact and high damping force engine mount featuring magnetorheological fluid (MRF). In the mount, a MR valve structure with both annular and radial flows is employed to generate a high damping force. First, the configuration and working principle of the proposed MR mount is introduced. The MRF flows in the mount are then analyzed and the governing equations of the MR mount are derived based on the Bingham plastic behavior of the MRF. An optimal design of the MR mount is then performed to find the optimal structure of the MR valve to generate a maximum damping force with certain design constraints. In addition, the gap size of MRF ducts is empirically chosen considering the ‘lockup’ problem of the mount at high frequency. Performance of the optimized MR mount is then evaluated based on finite element analysis and discussions on performance results of the optimized MR mount are given. The effectiveness of the proposed MR engine mount is demonstrated via computer simulation by presenting damping force and power consumption.

  12. Design of a Closed-Loop, Bidirectional Brain Machine Interface System With Energy Efficient Neural Feature Extraction and PID Control.

    Science.gov (United States)

    Liu, Xilin; Zhang, Milin; Richardson, Andrew G; Lucas, Timothy H; Van der Spiegel, Jan

    2017-08-01

    This paper presents a bidirectional brain machine interface (BMI) microsystem designed for closed-loop neuroscience research, especially experiments in freely behaving animals. The system-on-chip (SoC) consists of 16-channel neural recording front-ends, neural feature extraction units, 16-channel programmable neural stimulator back-ends, in-channel programmable closed-loop controllers, global analog-digital converters (ADC), and peripheral circuits. The proposed neural feature extraction units includes 1) an ultra low-power neural energy extraction unit enabling a 64-step natural logarithmic domain frequency tuning, and 2) a current-mode action potential (AP) detection unit with time-amplitude window discriminator. A programmable proportional-integral-derivative (PID) controller has been integrated in each channel enabling a various of closed-loop operations. The implemented ADCs include a 10-bit voltage-mode successive approximation register (SAR) ADC for the digitization of the neural feature outputs and/or local field potential (LFP) outputs, and an 8-bit current-mode SAR ADC for the digitization of the action potential outputs. The multi-mode stimulator can be programmed to perform monopolar or bipolar, symmetrical or asymmetrical charge balanced stimulation with a maximum current of 4 mA in an arbitrary channel configuration. The chip has been fabricated in 0.18 μ m CMOS technology, occupying a silicon area of 3.7 mm 2 . The chip dissipates 56 μW/ch on average. General purpose low-power microcontroller with Bluetooth module are integrated in the system to provide wireless link and SoC configuration. Methods, circuit techniques and system topology proposed in this work can be used in a wide range of relevant neurophysiology research, especially closed-loop BMI experiments.

  13. Key Features in Knowledge-Driven Companies

    Directory of Open Access Journals (Sweden)

    Dana NICULESCU

    2015-03-01

    Full Text Available In today’s Romanian business environment, an increasing attention should be laid on clarifying the organizational strategy, structures and systems within the corporate governance, and moreover a critical eye must be focused on the organizational culture, leadership, and alignment to ethical values. Organizational transparency makes sense rationally and ethically, therefore the business leaders and the top management must learn how to effectively build trust, communicate, and foster true values in a transparent manner. This paper proposes an introspective view over a Romanian entrepreneurial organization within the SME sector, where many and sudden changes at governance level took place in a relative short span of time, changes that influenced over time many critical aspects of human capital, including aspect of knowledge management. In our case, short-term gains prevailed over long-term interest and people were not prepared for these changes. By analyzing the effect of lack of transparency, communication and alignment over the employees’ engagement and involvement, the article draws on insights from different employees’ point of view, demonstrating that culture is capable of altering strategy and structure. The role of a leader of an organization is no longer simply to run the business on a daily basis, but to create the right culture based on ethics and values. It becomes essential to cultivate such a framework, based on leadership processes, toward achieving business objectives and related growth, profit, and return goals, outlining the future of corporate governance and what’s needed for continued effectiveness in a framework where knowledge is continually enhanced.

  14. Schizotypy: Key feature of Klinefelter's syndrome?

    NARCIS (Netherlands)

    Verhoeven, W.M.A.; Egger, J.I.M.

    2011-01-01

    Klinefelter's syndrome (KS; karyotype 47,XXY) is associated with specific neurocognitive impairments, especially delayed language development and impaired socioemotional evolution. There is an increased risk for psychiatric disturbances, particularly schizophrenia and affective spectrum disorders. A

  15. Toxicological features of maleilated polyflavonoids from Pinus radiata (D. Don.) as potential functional additives for biomaterials design.

    Science.gov (United States)

    García, Danny E; Medina, Paulina A; Zúñiga, Valentina I

    2017-11-01

    Polyflavonoids from Pinus radiata (D. Don.) are an abundant natural oligomers highly desirable as renewable chemicals. However, structural modification of polyflavonoids is a viable strategy in order to use such polyphenols as macrobuilding-blocks for biomaterial design. Polyflavonoids were esterified with three five-member cyclic anhydrides (maleic, itaconic, and citraconic) at 20 °C during 24 h in order to diversify physicochemical-, and biological-properties for agricultural, and food-packaging applications. In addition, the influence of the chemical modification, as well as the chemical structure of the grafting on toxicological features was evaluated. Structural features of derivatives were analyzed by spectroscopy (FT-IR and 1 H-NMR), and the degree of substitution was calculated. Toxicological profile was assessed by using three target species in a wide range of concentration (0.01-100 mgL - 1 ). Effect of polyflavonoids on the growth rate (Selenastrum capricornutum), mortality (Daphnia magna), and germination and radicle length (Lactuca sativa) was determined. Chemical modification affects the toxicological profile on the derivatives in a high extent. Results described remarkable differences in function of the target specie. The bioassays indicate differences of the polyflavonoids toxicological profile associated to the chemical structure of the grafting. Results allowed conclude that polyflavonoids from pine bark show slight toxic properties. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. The Identification, Implementation, and Evaluation of Critical User Interface Design Features of Computer-Assisted Instruction Programs in Mathematics for Students with Learning Disabilities

    Science.gov (United States)

    Seo, You-Jin; Woo, Honguk

    2010-01-01

    Critical user interface design features of computer-assisted instruction programs in mathematics for students with learning disabilities and corresponding implementation guidelines were identified in this study. Based on the identified features and guidelines, a multimedia computer-assisted instruction program, "Math Explorer", which delivers…

  17. Study design and the estimation of the size of key populations at risk of HIV: lessons from Viet Nam.

    Science.gov (United States)

    Safarnejad, Ali; Groot, Wim; Pavlova, Milena

    2018-01-30

    Estimation of the size of populations at risk of HIV is a key activity in the surveillance of the HIV epidemic. The existing framework for considering future research needs may provide decision-makers with a basis for a fair process of deciding on the methods of the estimation of the size of key populations at risk of HIV. This study explores the extent to which stakeholders involved with population size estimation agree with this framework, and thus, the study updates the framework. We conducted 16 in-depth interviews with key informants from city and provincial governments, NGOs, research institutes, and the community of people at risk of HIV. Transcripts were analyzed and reviewed for significant statements pertaining to criteria. Variations and agreement around criteria were analyzed, and emerging criteria were validated against the existing framework. Eleven themes emerged which are relevant to the estimation of the size of populations at risk of HIV in Viet Nam. Findings on missing criteria, inclusive participation, community perspectives and conflicting weight and direction of criteria provide insights for an improved framework for the prioritization of population size estimation methods. The findings suggest that the exclusion of community members from decision-making on population size estimation methods in Viet Nam may affect the validity, use, and efficiency of the evidence generated. However, a wider group of decision-makers, including community members among others, may introduce diverse definitions, weight and direction of criteria. Although findings here may not apply to every country with a transitioning economy or to every emerging epidemic, the principles of fair decision-making, value of community participation in decision-making and the expected challenges faced, merit consideration in every situation.

  18. The effects of the 'key' molar mass on the design of a cascade handling a multi-isotopic mixture

    International Nuclear Information System (INIS)

    Raichura, R.C.; Al-Janabi, M.A.M.

    1991-01-01

    The parameters required for describing the characteristics of separating units and cascades handling a multi-isotope mixture are first reviewed from previous work and then expressed in terms of a newly defined parameter called the 'Key' molar mass. The effects of the latter on the operating and economic parameters of a gas centrifuge cascade handling a multi-isotopic mixture are studied. Only cascades of the 'primitive' type, i.e. those in which the feed of a stage is made up of the light and heavy fractions of neighbouring stages, are considered. The costs incurred in obtaining outputs with specified concentrations are then discussed. (author)

  19. Design of a Secure Authentication and Key Agreement Scheme Preserving User Privacy Usable in Telecare Medicine Information Systems.

    Science.gov (United States)

    Arshad, Hamed; Rasoolzadegan, Abbas

    2016-11-01

    Authentication and key agreement schemes play a very important role in enhancing the level of security of telecare medicine information systems (TMISs). Recently, Amin and Biswas demonstrated that the authentication scheme proposed by Giri et al. is vulnerable to off-line password guessing attacks and privileged insider attacks and also does not provide user anonymity. They also proposed an improved authentication scheme, claiming that it resists various security attacks. However, this paper demonstrates that Amin and Biswas's scheme is defenseless against off-line password guessing attacks and replay attacks and also does not provide perfect forward secrecy. This paper also shows that Giri et al.'s scheme not only suffers from the weaknesses pointed out by Amin and Biswas, but it also is vulnerable to replay attacks and does not provide perfect forward secrecy. Moreover, this paper proposes a novel authentication and key agreement scheme to overcome the mentioned weaknesses. Security and performance analyses show that the proposed scheme not only overcomes the mentioned security weaknesses, but also is more efficient than the previous schemes.

  20. Wellness partners: design and evaluation of a web-based physical activity diary with social gaming features for adults.

    Science.gov (United States)

    Gotsis, Marientina; Wang, Hua; Spruijt-Metz, Donna; Jordan-Marsh, Maryalice; Valente, Thomas William

    2013-02-01

    The United States is currently in an age of obesity and inactivity despite increasing public awareness and scientific knowledge of detrimental long-term health effects of this lifestyle. Behavior-tracking diaries offer an effective strategy for physical activity adherence and weight management. Furthermore, Web-based physical activity diaries can engage meaningful partners in people's social networks through fun online gaming interactions and generate motivational mechanisms for effective behavioral change and positive health outcomes. Wellness Partners (WP) is a Web-based intervention in the form of a physical activity diary with social networking and game features. Two versions were designed and developed for the purpose of this study-"Diary" only and "Diary+Game". The objectives of this study included pilot testing the research process of this intervention design, implementation, evaluation, and exploring the effectiveness of social gaming features on adult participants' physical activity and anthropometric measures. We conducted a field experiment with randomized crossover design. Assessments occurred at baseline, first follow-up (FU, 5-8 weeks after using one version of WP), and second FU (5-8 weeks of using the other version of WP). In the control condition, participants started with the "Diary" version of WP while in the experimental condition, participants started with the "Diary+Game" version of WP. A total of 54 adults (egos) ages 44-88, and their family and friends (alters) ages 17-69 participated in the study in ego-network groups. Both egos and their alters completed online surveys about their exercise habits. In addition, egos completed anthropometric measurements of BMI, fat percentage, and fat mass by bioimpedance. From October 2009 to May 2010, flyers, emails, and Web advertisements yielded 335 volunteers who were screened. Rolling recruitment resulted in enrollment of 142 qualified participants in 54 ego-network groups, which were randomly

  1. Design and synthesis of fused polycycles via Diels-Alder reaction and ring-rearrangement metathesis as key steps.

    Science.gov (United States)

    Kotha, Sambasivarao; Ravikumar, Ongolu

    2015-01-01

    Atom efficient processes such as the Diels-Alder reaction (DA) and the ring-rearrangement metathesis (RRM) have been used to design new polycycles. In this regard, ruthenium alkylidene catalysts are effective in realizing the RRM of bis-norbornene derivatives prepared by DA reaction and Grignard addition. Here, fused polycycles are assembled which are difficult to produce by conventional synthetic routes.

  2. Modular Connector Keying Concept

    Science.gov (United States)

    Ishman, Scott; Dukes, Scott; Warnica, Gary; Conrad, Guy; Senigla, Steven

    2013-01-01

    For panel-mount-type connectors, keying is usually "built-in" to the connector body, necessitating different part numbers for each key arrangement. This is costly for jobs that require small quantities. This invention was driven to provide a cost savings and to reduce documentation of individual parts. The keys are removable and configurable in up to 16 combinations. Since the key parts are separate from the connector body, a common design can be used for the plug, receptacle, and key parts. The keying can then be set at the next higher assembly.

  3. Design and synthesis of fused polycycles via Diels–Alder reaction and ring-rearrangement metathesis as key steps

    Directory of Open Access Journals (Sweden)

    Sambasivarao Kotha

    2015-07-01

    Full Text Available Atom efficient processes such as the Diels–Alder reaction (DA and the ring-rearrangement metathesis (RRM have been used to design new polycycles. In this regard, ruthenium alkylidene catalysts are effective in realizing the RRM of bis-norbornene derivatives prepared by DA reaction and Grignard addition. Here, fused polycycles are assembled which are difficult to produce by conventional synthetic routes.

  4. Designing Integrated Approaches to Support People with Multimorbidity: Key Messages from Systematic Reviews, Health System Leaders and Citizens.

    Science.gov (United States)

    Wilson, Michael G; Lavis, John N; Gauvin, Francois-Pierre

    2016-11-01

    Living with multiple chronic conditions (multimorbidity) - and facing complex, uncoordinated and fragmented care - is part of the daily life of a growing number of Canadians. We undertook: a knowledge synthesis; a "gap analysis" of existing systematic reviews; an issue brief that synthesized the available evidence about the problem, three options for addressing it and implementation considerations; a stakeholder dialogue involving key health-system leaders; and a citizen panel. We identified several recommendations for actions that can be taken, including: developing evidence-based guidance that providers can use to help achieve goals set by patients; embracing approaches to supporting self-management; supporting greater communication and collaboration across healthcare providers as well as between healthcare providers and patients; and investing more efforts in health promotion and disease prevention. Our results point to the need for health system decision-makers to support bottom-up, person-centred approaches to developing models of care that are tailored for people with multimorbidity and support a research agenda to address the identified priorities. Copyright © 2016 Longwoods Publishing.

  5. [Key points for esthetic rehabilitation of anterior teeth using chair-side computer aided design and computer aided manufacture technique].

    Science.gov (United States)

    Yang, J; Feng, H L

    2018-04-09

    With the rapid development of the chair-side computer aided design and computer aided manufacture (CAD/CAM) technology, its accuracy and operability of have been greatly improved in recent years. Chair-side CAD/CAM system may produce all kinds of indirect restorations, and has the advantages of rapid, accurate and stable production. It has become the future development direction of Stomatology. This paper describes the clinical application of the chair-side CAD/CAM technology for anterior aesthetic restorations from the aspects of shade and shape.

  6. An analytic Study of the Key Factors In uencing the Design and Routing Techniques of a Wireless Sensor Network

    Directory of Open Access Journals (Sweden)

    Yogita Bahuguna

    2017-03-01

    Full Text Available A wireless sensor network contains various nodes having certain sensing, processing and communication capabilities. Actually they are multifunctional battery operated nodes called motes. These motes are small in size and battery constrained. They are operated by a power source. A wireless sensor network consists of a huge number of tiny sensor nodes which are deployed either randomly or according to some predefined distribution. The sensors nodes in a sensor network are cooperative among themselves having self-organizing ability. This ensures that a wireless network serves a wide variety of applications. Few of them are weather monitoring, health, security and military etc. As their applications are wide, this requires that sensors in a sensor network must play their role very efficiently. But, as discussed above, the sensor nodes have energy limitation. This limitation leads failure of nodes after certain round of communication. So, a sensor network suffers with sensors having energy limitations. Beside this, sensor nodes in a sensor network must fulfill connectivity and coverage requirements. In this paper, we have discussed various issues affecting the design of a wireless sensor network. This provides the readers various research issues in designing a wireless sensor network.

  7. Just-in-Time Adaptive Interventions (JITAIs) in Mobile Health: Key Components and Design Principles for Ongoing Health Behavior Support.

    Science.gov (United States)

    Nahum-Shani, Inbal; Smith, Shawna N; Spring, Bonnie J; Collins, Linda M; Witkiewitz, Katie; Tewari, Ambuj; Murphy, Susan A

    2018-05-18

    The just-in-time adaptive intervention (JITAI) is an intervention design aiming to provide the right type/amount of support, at the right time, by adapting to an individual's changing internal and contextual state. The availability of increasingly powerful mobile and sensing technologies underpins the use of JITAIs to support health behavior, as in such a setting an individual's state can change rapidly, unexpectedly, and in his/her natural environment. Despite the increasing use and appeal of JITAIs, a major gap exists between the growing technological capabilities for delivering JITAIs and research on the development and evaluation of these interventions. Many JITAIs have been developed with minimal use of empirical evidence, theory, or accepted treatment guidelines. Here, we take an essential first step towards bridging this gap. Building on health behavior theories and the extant literature on JITAIs, we clarify the scientific motivation for JITAIs, define their fundamental components, and highlight design principles related to these components. Examples of JITAIs from various domains of health behavior research are used for illustration. As we enter a new era of technological capacity for delivering JITAIs, it is critical that researchers develop sophisticated and nuanced health behavior theories capable of guiding the construction of such interventions. Particular attention has to be given to better understanding the implications of providing timely and ecologically sound support for intervention adherence and retention.

  8. Integrating valve-inspired design features into poly(ethylene glycol) hydrogel scaffolds for heart valve tissue engineering.

    Science.gov (United States)

    Zhang, Xing; Xu, Bin; Puperi, Daniel S; Yonezawa, Aline L; Wu, Yan; Tseng, Hubert; Cuchiara, Maude L; West, Jennifer L; Grande-Allen, K Jane

    2015-03-01

    The development of advanced scaffolds that recapitulate the anisotropic mechanical behavior and biological functions of the extracellular matrix in leaflets would be transformative for heart valve tissue engineering. In this study, anisotropic mechanical properties were established in poly(ethylene glycol) (PEG) hydrogels by crosslinking stripes of 3.4 kDa PEG diacrylate (PEGDA) within 20 kDa PEGDA base hydrogels using a photolithographic patterning method. Varying the stripe width and spacing resulted in a tensile elastic modulus parallel to the stripes that was 4.1-6.8 times greater than that in the perpendicular direction, comparable to the degree of anisotropy between the circumferential and radial orientations in native valve leaflets. Biomimetic PEG-peptide hydrogels were prepared by tethering the cell-adhesive peptide RGDS and incorporating the collagenase-degradable peptide PQ (GGGPQG↓IWGQGK) into the polymer network. The specific amounts of RGDS and PEG-PQ within the resulting hydrogels influenced the elongation, de novo extracellular matrix deposition and hydrogel degradation behavior of encapsulated valvular interstitial cells (VICs). In addition, the morphology and activation of VICs grown atop PEG hydrogels could be modulated by controlling the concentration or micro-patterning profile of PEG-RGDS. These results are promising for the fabrication of PEG-based hydrogels using anatomically and biologically inspired scaffold design features for heart valve tissue engineering. Copyright © 2014 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

  9. The Design Features of Complex Vessels of Malyshev Neolithic Culture of Lower Priamurye (case study: Malyshevo 1 Settlement

    Directory of Open Access Journals (Sweden)

    Inga V. Filatova

    2015-03-01

    Full Text Available According to the author’s opinion, the solution for cultural genesis issues can be tackled through the analysis of structural peculiarities of hollow bodies of vessels of different ceramic complexes. The ceramics of the Malyshev Culture of the Lower Amur is no exception. The article traces the evolution of researchers’ views in regard to Neolithic culture in inner periodization of the region as well as cultural relevance of early complex ceramics by a well known Soviet archeologist academic A.P. Okladnykov – stage of Lower Amur Neolithic culture. Case study: visualization of ceramic collection of one-layer Neolithic settlement Malyshevo-1 (“At the craftsmen”. Here we identify two vessel groups, which differ through their morphological and decorative features. On the ground of technological assessments of manufacturing techniques by I. G. Glushkov (1996, including methodological developments by A. A. Bobrinsky (1978, the program of hollow body design is researched. The manufacturing techniques are identified (methods of fixing, build-up, straps oiling, types of molding, filling program, cutting and bottom fixing. The mixed programs of hollow body vessels are identified and locations of two pottery traditions are found. A competitive analysis for identifying the peculiarities of Malyshev ceramics and Neolithic materials of the Lower Amur and bordering seaside territories. There are similarities are drawn out between ceramic complexes of Osipov culture of early Neolithic (Lower Amur and Rudninsky culture (Rudninsky type, Sergeev type of early Neolithic (seaside territories.

  10. Exergetic optimization of a key design parameter in heat pump systems with economizer coupled with scroll compressor

    International Nuclear Information System (INIS)

    Ma, Guoyuan; Li, Xianguo

    2007-01-01

    The heat pump system with economizer coupled with scroll compressor can extend effectively its operating ranges and provide a technological method to enable the heat pump to run steadily and efficiently in severe weather conditions. The intermediate pressure, namely the working pressure of the refrigerant in the economizer, is an essential design parameter and affects crucially the performances of the heat pump system. According to the exergetic model setup for the heat pump system based on the second law of thermodynamics, the influences of the intermediate pressure on the performances are comprehensively analyzed using experimental data of the heat pump prototype. It is found that the optimal relative intermediate pressure (RIP) is between 1.1 and 1.3

  11. Recommendations for sex/gender neuroimaging research: Key principles and implications for research design, analysis and interpretation

    Directory of Open Access Journals (Sweden)

    Gina eRippon

    2014-08-01

    Full Text Available For over a decade, neuroimaging (NI technologies have had an increasing impact in the study of complex cognitive and social processes. In this emerging field of social cognitive neuroscience, a central goal should be to increase the understanding of the interaction between the neurobiology of the individual and the environment in which s/he develops and functions. The study of the relationship between sex and gender could offer a valuable example of such research. We identify here four main principles that should inform NI research. First, the principle of overlap, arising from evidence of significant overlap of female/male distributions on measures of many gendered behaviours. Second, the principle of mosaicism, arising from evidence that for both behaviour and brain, each individual manifests a complex and idiosyncratic combination of feminine and masculine characteristics. Third, the principle of contingency, arising from evidence that female/male behavioural differences are contingent on time, place, social group and context. Fourth, the principle of entanglement, arising from an awareness that the neural phenotypes that NI techniques measure are a function of the interactive and reciprocal influence of biology and environment. These important principles have emerged and become well-established over the past few decades, but their implications are often not reflected in the design and interpretation of NI sex/gender research. We therefore offer a set of guidelines for researchers to ensure that NI sex/gender research is appropriately designed and interpreted. We hope this ‘toolkit’ will also be of use to editorial boards and journal reviewers, as well as those who view, communicate and interpret such research.

  12. Submersible Aircraft Concept Design Study - Amendment 1. Additional Assessment of Design Risks & Sensitivities within the Original Study, and an Initial Assessment of Key Control Aspects

    Science.gov (United States)

    2011-02-01

    http://www.redhammer.se/tornado/index.html (3) Aircraft Design: A Conceptual Approach, Daniel P. Raymer , AIAA, 1992 (4) (5) Moran, J., Computational...Fluid Dynamics, Wiley & Sons, 1984. Notes on the Stability and Control of Tailless Airplanes, Robert T. Jones, NACA Technical Note No.837, December

  13. Mathematical Modeling Analysis and Optimization of Key Design Parameters of Proton-Conductive Solid Oxide Fuel Cells

    Directory of Open Access Journals (Sweden)

    Hong Liu

    2014-01-01

    Full Text Available A proton-conductive solid oxide fuel cell (H-SOFC has the advantage of operating at higher temperatures than a PEM fuel cell, but at lower temperatures than a SOFC. This study proposes a mathematical model for an H-SOFC in order to simulate the performance and optimize the flow channel designs. The model analyzes the average mass transfer and species’ concentrations in flow channels, which allows the determination of an average concentration polarization in anode and cathode gas channels, the proton conductivity of electrolyte membranes, as well as the activation polarization. An electrical circuit for the current and proton conduction is applied to analyze the ohmic losses from an anode current collector to a cathode current collector. The model uses relatively less amount of computational time to find the V-I curve of the fuel cell, and thus it can be applied to compute a large amount of cases with different flow channel dimensions and operating parameters for optimization. The modeling simulation results agreed satisfactorily with the experimental results from literature. Simulation results showed that a relatively small total width of flow channel and rib, together with a small ratio of the rib’s width versus the total width, are preferable for obtaining high power densities and thus high efficiency.

  14. Testing Map Features Designed to Convey the Uncertainty of Cancer Risk: Insights Gained From Assessing Judgments of Information Adequacy and Communication Goals.

    Science.gov (United States)

    Severtson, Dolores J

    2015-02-01

    Barriers to communicating the uncertainty of environmental health risks include preferences for certain information and low numeracy. Map features designed to communicate the magnitude and uncertainty of estimated cancer risk from air pollution were tested among 826 participants to assess how map features influenced judgments of adequacy and the intended communication goals. An uncertain versus certain visual feature was judged as less adequate but met both communication goals and addressed numeracy barriers. Expressing relative risk using words communicated uncertainty and addressed numeracy barriers but was judged as highly inadequate. Risk communication and visual cognition concepts were applied to explain findings.

  15. Cross-sector surveys assessing perceptions of key stakeholders towards barriers, concerns and facilitators to the appropriate use of adaptive designs in confirmatory trials.

    Science.gov (United States)

    Dimairo, Munyaradzi; Julious, Steven A; Todd, Susan; Nicholl, Jonathan P; Boote, Jonathan

    2015-12-23

    Appropriately conducted adaptive designs (ADs) offer many potential advantages over conventional trials. They make better use of accruing data, potentially saving time, trial participants, and limited resources compared to conventional, fixed sample size designs. However, one can argue that ADs are not implemented as often as they should be, particularly in publicly funded confirmatory trials. This study explored barriers, concerns, and potential facilitators to the appropriate use of ADs in confirmatory trials among key stakeholders. We conducted three cross-sectional, online parallel surveys between November 2014 and January 2015. The surveys were based upon findings drawn from in-depth interviews of key research stakeholders, predominantly in the UK, and targeted Clinical Trials Units (CTUs), public funders, and private sector organisations. Response rates were as follows: 30(55 %) UK CTUs, 17(68 %) private sector, and 86(41 %) public funders. A Rating Scale Model was used to rank barriers and concerns in order of perceived importance for prioritisation. Top-ranked barriers included the lack of bridge funding accessible to UK CTUs to support the design of ADs, limited practical implementation knowledge, preference for traditional mainstream designs, difficulties in marketing ADs to key stakeholders, time constraints to support ADs relative to competing priorities, lack of applied training, and insufficient access to case studies of undertaken ADs to facilitate practical learning and successful implementation. Associated practical complexities and inadequate data management infrastructure to support ADs were reported as more pronounced in the private sector. For funders of public research, the inadequate description of the rationale, scope, and decision-making criteria to guide the planned AD in grant proposals by researchers were all viewed as major obstacles. There are still persistent and important perceptions of individual and organisational obstacles

  16. Effect of Inquiry-Based Computer Simulation Modeling on Pre-Service Teachers' Understanding of Homeostasis and Their Perceptions of Design Features

    Science.gov (United States)

    Chabalengula, Vivien; Fateen, Rasheta; Mumba, Frackson; Ochs, Laura Kathryn

    2016-01-01

    This study investigated the effect of an inquiry-based computer simulation modeling (ICoSM) instructional approach on pre-service science teachers' understanding of homeostasis and its related concepts, and their perceived design features of the ICoSM and simulation that enhanced their conceptual understanding of these concepts. Fifty pre-service…

  17. The Tobacco Pack Surveillance System: A Protocol for Assessing Health Warning Compliance, Design Features, and Appeals of Tobacco Packs Sold in Low- and Middle-Income Countries.

    Science.gov (United States)

    Smith, Katherine; Washington, Carmen; Brown, Jennifer; Vadnais, Alison; Kroart, Laura; Ferguson, Jacqueline; Cohen, Joanna

    2015-01-01

    Tobacco remains the world's leading preventable cause of death, with the majority of tobacco-caused deaths occurring in low- and middle-income countries. The first global health treaty, the Framework Convention on Tobacco Control (FCTC), outlines a set of policy initiatives that have been demonstrated as effective in reducing tobacco use. Article 11 of the FCTC focuses on using the tobacco package to communicate tobacco-caused harms; it also seeks to restrict the delivery of misleading information about the product on the pack. The objective of this study was to establish a surveillance system for tobacco packs in the 14 low- and middle-income countries with the greatest number of smokers. The Tobacco Pack Surveillance System (TPackSS) monitors whether required health warnings on tobacco packages are being implemented as intended, and identifies pack designs and appeals that might violate or detract from the communication of harm-related information and undermine the impact of a country's tobacco packaging laws. The protocol outlined is intended to be applicable or adaptable for surveillance efforts in other countries. Tobacco packs were collected in 14 countries during 2013. The intention was, to the extent possible, to construct a census of "unique" pack presentations available for purchase in each country. The TPackSS team partnered with in-country field staff to implement a standardized protocol for acquiring packs from 36 diverse neighborhoods across three cities in each country. At the time of purchase, data on price and place of acquisition of each pack was recorded. The field staff, according to a standardized protocol, then photographed packs before they were shipped to the United States for coding and archiving. Each pack was coded for compliance with the country-specific health warning label laws, as well as for key design features of the pack and appeals of the branding elements. The coding protocols were developed based upon prior research, expert

  18. Key Recovery Attacks on Recent Authenticated Ciphers

    DEFF Research Database (Denmark)

    Bogdanov, Andrey; Dobraunig, Christoph; Eichlseder, Maria

    2014-01-01

    In this paper, we cryptanalyze three authenticated ciphers: AVALANCHE, Calico, and RBS. While the former two are contestants in the ongoing international CAESAR competition for authenticated encryption schemes, the latter has recently been proposed for lightweight applications such as RFID systems...... and wireless networks. All these schemes use well-established and secure components such as the AES, Grain-like NFSRs, ChaCha and SipHash as their building blocks. However, we discover key recovery attacks for all three designs, featuring square-root complexities. Using a key collision technique, we can...

  19. Design considerations of high-performance InGaAs/InP single-photon avalanche diodes for quantum key distribution.

    Science.gov (United States)

    Ma, Jian; Bai, Bing; Wang, Liu-Jun; Tong, Cun-Zhu; Jin, Ge; Zhang, Jun; Pan, Jian-Wei

    2016-09-20

    InGaAs/InP single-photon avalanche diodes (SPADs) are widely used in practical applications requiring near-infrared photon counting such as quantum key distribution (QKD). Photon detection efficiency and dark count rate are the intrinsic parameters of InGaAs/InP SPADs, due to the fact that their performances cannot be improved using different quenching electronics given the same operation conditions. After modeling these parameters and developing a simulation platform for InGaAs/InP SPADs, we investigate the semiconductor structure design and optimization. The parameters of photon detection efficiency and dark count rate highly depend on the variables of absorption layer thickness, multiplication layer thickness, excess bias voltage, and temperature. By evaluating the decoy-state QKD performance, the variables for SPAD design and operation can be globally optimized. Such optimization from the perspective of specific applications can provide an effective approach to design high-performance InGaAs/InP SPADs.

  20. Gridded Surface Subsurface Hydrologic Analysis Modeling for Analysis of Flood Design Features at the Picayune Strand Restoration Project

    Science.gov (United States)

    2016-08-01

    restore its predrainage hydrology and ecological function for beneficial effects on flora and fauna in the project area and surrounding public lands. The...partnership with South Florida Water Management District (SFWMD), is constructing these features. Engineering support is required for hydrologic and...simulation accuracy and related resource requirements. Spatial data products such as digital elevation models, surveyed channel cross sections, soil

  1. Review of Marmasoma White with lectotype designation of M. sumptuosum White and an identification key to the Australasian/Oceanian genera of Ecliminae (Diptera, Bombyliidae).

    Science.gov (United States)

    Rodrigues, Paula Fernanda Motta; McAlister, Erica; Lamas, Carlos José Einicker

    2017-02-15

    The bombyliid genus Marmasoma White is restricted to Australia. Marmasoma sumptuosum White, the only known species of the genus, is studied and a lectotype and paralectotypes are designated. Based on the type series and on additional material, a redescription of the species is presented and the main characters of the external morphology of adults are illustrated and photographed, including male and female genitalia. In addition, the remarkable aedeagus of M. sumptuosum, unique among all Ecliminae species by the presence of serrated projections on its apical portion, is described and photographed in detail for the first time. An identification key to the Australasian/Oceanian genera of Ecliminae and a distribution map with the known geographic records of Marmasoma are also included.

  2. Specific features of organizng the computer-aided design of radio-electronic equipment for electrophysical facilities

    International Nuclear Information System (INIS)

    Mozin, I.V.; Vasil'ev, M.P.

    1985-01-01

    Problems of developing systems for computer-aided design (CAD) of radioelectronic equipment for large electrophysical facilities such as charged particle accelerators of new generation are discussed. The PLATA subsystem representing a part of CAD and used for printed circuit design is described. The subsystem PLATA is utilized to design, on the average, up to 150 types of circuits a year, 100-120 of which belong to circuits of increased complexity. In this case labour productivity of a designer at documentation increases almost two times

  3. The use of engineering features and schematic solutions of propulsion nuclear steam supply systems for floating nuclear power plant design

    International Nuclear Information System (INIS)

    Achkasov, A.N.; Grechko, G.I.; Pepa, V.N.; Shishkin, V.A.

    2000-01-01

    In recent years many countries and the international community represented by the IAEA have shown a notable interest in designing small and medium size nuclear power plants intended for electricity and heat generation for remote areas. These power plants can be also used for desalination purposes. As these nuclear plants are planned for use in areas without a well-developed power grid, the design shall account for their transportation to the site in complete preparedness for operation. Since the late 80s, the Research and Development Institute of Power Engineering (RDIPE) has carried out active efforts in designing reactor facilities for floating nuclear power plants. This work relies on the long-term experience of RDIPE engineers in designing the propulsion NSSS. Advantages can be gained from the specific engineering solutions that are already applied in the design of propulsion Nuclear Steam Supply System (NSSS) or from development of new designs based on the proven technologies. Successful implementation of the experience has been made easier owing to rather similar design requirements prescribed to ship-mounted NSSS and floating NPP. The common design targets are, in particular, minimization of mass and dimensions, resistance to such external impacts as rolling, heel and trim, operability in case of running aground or collision with other ships, etc. (author)

  4. Concepts, features, and design of a sixteen-to-four beam combiner for ILSE [Induction Linac Systems Experiment

    International Nuclear Information System (INIS)

    Judd, D.L.; Celata, C.; Close, E.; Faltens, A.; Hahn, K.; La Mon, K.; Lee, E.P.; Smith, L.; Thur, W.

    1989-03-01

    Sixteen intense parallel ion beams are to be transversely combined into four by dispersionless double bends. Emittance growth due to electrostatic energy redistribution and to the geometry is evaluated. Most bending elements are electric, and alternate with AG electrostatic quadrupoles similar to those upstream. The final elements are magnetic, combining focusing and ''unbending''. Electrode shapes and pulsed-current arrays (having very small clearances), and mechanical and electric features of the combiner, and described. 1 ref., 7 figs

  5. A combined Fisher and Laplacian score for feature selection in QSAR based drug design using compounds with known and unknown activities.

    Science.gov (United States)

    Valizade Hasanloei, Mohammad Amin; Sheikhpour, Razieh; Sarram, Mehdi Agha; Sheikhpour, Elnaz; Sharifi, Hamdollah

    2018-02-01

    Quantitative structure-activity relationship (QSAR) is an effective computational technique for drug design that relates the chemical structures of compounds to their biological activities. Feature selection is an important step in QSAR based drug design to select the most relevant descriptors. One of the most popular feature selection methods for classification problems is Fisher score which aim is to minimize the within-class distance and maximize the between-class distance. In this study, the properties of Fisher criterion were extended for QSAR models to define the new distance metrics based on the continuous activity values of compounds with known activities. Then, a semi-supervised feature selection method was proposed based on the combination of Fisher and Laplacian criteria which exploits both compounds with known and unknown activities to select the relevant descriptors. To demonstrate the efficiency of the proposed semi-supervised feature selection method in selecting the relevant descriptors, we applied the method and other feature selection methods on three QSAR data sets such as serine/threonine-protein kinase PLK3 inhibitors, ROCK inhibitors and phenol compounds. The results demonstrated that the QSAR models built on the selected descriptors by the proposed semi-supervised method have better performance than other models. This indicates the efficiency of the proposed method in selecting the relevant descriptors using the compounds with known and unknown activities. The results of this study showed that the compounds with known and unknown activities can be helpful to improve the performance of the combined Fisher and Laplacian based feature selection methods.

  6. Design and development of a MLS based compact active suspension system, featuring air spring and energy harvesting capabilities

    DEFF Research Database (Denmark)

    Berg, Nick Ilsø; Holm, Rasmus Koldborg; Rasmussen, Peter Omand

    2016-01-01

    This paper describes the design and development of an novel Magnetic Lead Screw based active suspension system for passenger vehicles, using a new MLS topology. The design is based on performance specifications found from ISO road profiles, with a maximum harvested energy approach. By integrating...... the PMSM motor with the MLS, it possible to construct a very compact design with an integrated air spring. The prototype is build and frictional losses and efficiency for the MLS damper unit are measured. Additional the stall force and stall torque are measured for the build prototype to validate...

  7. Review of Current State of the Art and Key Design Issues With Potential Solutions for Liquid Hydrogen Cryogenic Storage Tank Structures for Aircraft Applications

    Science.gov (United States)

    Mital, Subodh K.; Gyekenyesi, John Z.; Arnold, Steven M.; Sullivan, Roy M.; Manderscheid, Jane M.; Murthy, Pappu L. N.

    2006-01-01

    Due to its high specific energy content, liquid hydrogen (LH2) is emerging as an alternative fuel for future aircraft. As a result, there is a need for hydrogen tank storage systems, for these aircraft applications, that are expected to provide sufficient capacity for flight durations ranging from a few minutes to several days. It is understood that the development of a large, lightweight, reusable cryogenic liquid storage tank is crucial to meet the goals of and supply power to hydrogen-fueled aircraft, especially for long flight durations. This report provides an annotated review (including the results of an extensive literature review) of the current state of the art of cryogenic tank materials, structural designs, and insulation systems along with the identification of key challenges with the intent of developing a lightweight and long-term storage system for LH2. The broad classes of insulation systems reviewed include foams (including advanced aerogels) and multilayer insulation (MLI) systems with vacuum. The MLI systems show promise for long-term applications. Structural configurations evaluated include single- and double-wall constructions, including sandwich construction. Potential wall material candidates are monolithic metals as well as polymer matrix composites and discontinuously reinforced metal matrix composites. For short-duration flight applications, simple tank designs may suffice. Alternatively, for longer duration flight applications, a double-wall construction with a vacuum-based insulation system appears to be the most optimum design. The current trends in liner material development are reviewed in the case that a liner is required to minimize or eliminate the loss of hydrogen fuel through permeation.

  8. Proposal to negotiate extensions to four collaboration agreements for the design of key components of the beam-delivery and linac systems for the Compact Linear Collider (CLIC) for a duration of two years

    CERN Document Server

    2017-01-01

    Proposal to negotiate extensions to four collaboration agreements for the design of key components of the beam-delivery and linac systems for the Compact Linear Collider (CLIC) for a duration of two years

  9. Designing and evaluating symbols for electronic displays of navigation information : symbol stereotypes and symbol-feature rules

    Science.gov (United States)

    2005-09-30

    There is currently no common symbology standard for the electronic display of navigation information. The wide range of display technology and the different functions these displays support makes it difficult to design symbols that are easily recogni...

  10. Dissecting the functional role of key residues in triheme cytochrome PpcA: a path to rational design of G. sulfurreducens strains with enhanced electron transfer capabilities.

    Directory of Open Access Journals (Sweden)

    Leonor Morgado

    Full Text Available PpcA is the most abundant member of a family of five triheme cytochromes c7 in the bacterium Geobacter sulfurreducens (Gs and is the most likely carrier of electrons destined for outer surface during respiration on solid metal oxides, a process that requires extracellular electron transfer. This cytochrome has the highest content of lysine residues (24% among the family, and it was suggested to be involved in e-/H(+ energy transduction processes. In the present work, we investigated the functional role of lysine residues strategically located in the vicinity of each heme group. Each lysine was replaced by glutamine or glutamic acid to evaluate the effects of a neutral or negatively charged residue in each position. The results showed that replacing Lys9 (located near heme IV, Lys18 (near heme I or Lys22 (between hemes I and III has essentially no effect on the redox properties of the heme groups and are probably involved in redox partner recognition. On the other hand, Lys43 (near heme IV, Lys52 (between hemes III and IV and Lys60 (near heme III are crucial in the regulation of the functional mechanism of PpcA, namely in the selection of microstates that allow the protein to establish preferential e-/H(+ transfer pathways. The results showed that the preferred e-/H(+ transfer pathways are only established when heme III is the last heme to oxidize, a feature reinforced by a higher difference between its reduction potential and that of its predecessor in the order of oxidation. We also showed that K43 and K52 mutants keep the mechanistic features of PpcA by establishing preferential e-/H+ transfer pathways at lower reduction potential values than the wild-type protein, a property that can enable rational design of Gs strains with optimized extracellular electron transfer capabilities.

  11. Features of Designing the Criterion-Based Rehabilitation Program for Patients after Arthroscopic Reconstruction of the Anterior Cruciate Ligament

    Directory of Open Access Journals (Sweden)

    I.V. Roy

    2016-04-01

    Full Text Available The article presents an innovative criterion-based rehabilitation program for patients, who underwent arthroscopic reconstruction of the anterior cruciate ligament. The features of the program are described, methodological foundations to perform permissible exercises are presented for each periods of the program, which correspond to a specific motor mode. The degree of preparedness of the patient is determined by the criterion of performance of the test exercises that will permit him to the loads of a new, higher level of trainings. The effectiveness of the developed program is confirmed clinically.

  12. Key thrusts in next generation CANDU. Annex 10

    International Nuclear Information System (INIS)

    Shalaby, B.A.; Torgerson, D.F.; Duffey, R.B.

    2002-01-01

    Current electricity markets and the competitiveness of other generation options such as CCGT have influenced the directions of future nuclear generation. The next generation CANDU has used its key characteristics as the basis to leap frog into a new design featuring improved economics, enhanced passive safety, enhanced operability and demonstrated fuel cycle flexibility. Many enabling technologies spinning of current CANDU design features are used in the next generation design. Some of these technologies have been developed in support of existing plants and near term designs while others will need to be developed and tested. This paper will discuss the key principles driving the next generation CANDU design and the fuel cycle flexibility of the CANDU system which provide synergism with the PWR fuel cycle. (author)

  13. A discussion of key values to inform the design and delivery of services for HIV-affected women and couples attempting pregnancy in resource-constrained settings.

    Science.gov (United States)

    Heffron, Renee; Davies, Natasha; Cooke, Ian; Kaida, Angela; Mergler, Reid; van der Poel, Sheryl; Cohen, Craig R; Mmeje, Okeoma

    2015-01-01

    HIV-affected women and couples often desire children and many accept HIV risk in order to attempt pregnancy and satisfy goals for a family. Risk reduction strategies to mitigate sexual and perinatal HIV transmission include biomedical and behavioural approaches. Current efforts to integrate HIV and reproductive health services offer prime opportunities to incorporate strategies for HIV risk reduction during pregnancy attempts. Key client and provider values about services to optimize pregnancy in the context of HIV risk provide insights for the design and implementation of large-scale "safer conception" programmes. Through our collective experience and discussions at a multi-disciplinary international World Health Organization-convened workshop to initiate the development of guidelines and an algorithm of care to support the delivery of services for HIV-affected women and couples attempting pregnancy, we identified four values that are key to the implementation of these programmes: (1) understanding fertility care and an ability to identify potential fertility problems; (2) providing equity of access to resources enabling informed decision-making about reproductive choices; (3) creating enabling environments that reduce stigma associated with HIV and infertility; and (4) creating enabling environments that encourage disclosure of HIV status and fertility status to partners. Based on these values, recommendations for programmes serving HIV-affected women and couples attempting pregnancy include the following: incorporation of comprehensive reproductive health counselling; training to support the transfer and exchange of knowledge between providers and clients; care environments that reduce the stigma of childbearing among HIV-affected women and couples; support for safe and voluntary disclosure of HIV and fertility status; and increased efforts to engage men in reproductive decision-making at times that align with women's desires. Programmes, policies and guidelines

  14. Design features of BREST reactors. Experimental work to advance the concept of BREST reactors. Results and plans

    International Nuclear Information System (INIS)

    Filin, A.I.; Orlov, V.V.; Leonov, V.N.; Sila-Novitskij, A.G.; Smirnov, V.S.; Tsikunov, V.S.

    2001-01-01

    Principle designs of 300 MW(th) and 1200 MW(th) lead-cooled fast reactors are presented. Reactors of various output are shown to be built using the same principles. In conjunction with increased output and to implement inherent safety concept in BREST-1200 reactor design a number of new solutions, which may be used in BREST-300 concept too, has been taken including: pool-type reactor design not requiring metal vessel, hence, not limiting reactor power; new handling system allowing to reduce central hall and building dimensions as a whole; emergency cooling system using Field pipes, immersed directly in lead, which may be used to cool down reactor under normal conditions; by-pass line incorporated in coolant loop allowing to refuse the actively actuating valve initiated in pumps shut down. (author)

  15. Design Features for Linguistically-Mediated Meaning Construction: The Relative Roles of the Linguistic and Conceptual Systems in Subserving the Ideational Function of Language.

    Science.gov (United States)

    Evans, Vyvyan

    2016-01-01

    Recent research in language and cognitive science proposes that the linguistic system evolved to provide an "executive" control system on the evolutionarily more ancient conceptual system (e.g., Barsalou et al., 2008; Evans, 2009, 2015a,b; Bergen, 2012). In short, the claim is that embodied representations in the linguistic system interface with non-linguistic representations in the conceptual system, facilitating rich meanings, or simulations, enabling linguistically mediated communication. In this paper I build on these proposals by examining the nature of what I identify as design features for this control system. In particular, I address how the ideational function of language-our ability to deploy linguistic symbols to convey meanings of great complexity-is facilitated. The central proposal of this paper is as follows. The linguistic system of any given language user, of any given linguistic system-spoken or signed-facilitates access to knowledge representation-concepts-in the conceptual system, which subserves this ideational function. In the most general terms, the human meaning-making capacity is underpinned by two distinct, although tightly coupled representational systems: the conceptual system and the linguistic system. Each system contributes to meaning construction in qualitatively distinct ways. This leads to the first design feature: given that the two systems are representational-they are populated by semantic representations-the nature and function of the representations are qualitatively different. This proposed design feature I term the bifurcation in semantic representation. After all, it stands to reason that if a linguistic system has a different function, vis-à-vis the conceptual system, which is of far greater evolutionary antiquity, then the semantic representations will be complementary, and as such, qualitatively different, reflecting the functional distinctions of the two systems, in collectively giving rise to meaning. I consider the

  16. Identifying Effective Design Features of Technology-Infused Inquiry Learning Modules: A Two-Year Study of Students' Inquiry Abilities

    Science.gov (United States)

    Hsu, Ying-Shao; Fang, Su-Chi; Zhang, Wen-Xin; Hsin-Kai, Wu; Wu, Pai-Hsing; Hwang, Fu-Kwun

    2016-01-01

    The two-year study aimed to explore how students' development of different inquiry abilities actually benefited from the design of technology-infused learning modules. Three learning modules on the topics of seasons, environmental issues and air pollution were developed to facilitate students' inquiry abilities: questioning, planning, analyzing,…

  17. Validation of newly developed and redesigned key indicator methods for assessment of different working conditions with physical workloads based on mixed-methods design: a study protocol.

    Science.gov (United States)

    Klussmann, Andre; Liebers, Falk; Brandstädt, Felix; Schust, Marianne; Serafin, Patrick; Schäfer, Andreas; Gebhardt, Hansjürgen; Hartmann, Bernd; Steinberg, Ulf

    2017-08-21

    The impact of work-related musculoskeletal disorders is considerable. The assessment of work tasks with physical workloads is crucial to estimate the work-related health risks of exposed employees. Three key indicator methods are available for risk assessment regarding manual lifting, holding and carrying of loads; manual pulling and pushing of loads; and manual handling operations. Three further KIMs for risk assessment regarding whole-body forces, awkward body postures and body movement have been developed de novo. In addition, the development of a newly drafted combined method for mixed exposures is planned. All methods will be validated regarding face validity, reliability, convergent validity, criterion validity and further aspects of utility under practical conditions. As part of the joint project MEGAPHYS (multilevel risk assessment of physical workloads), a mixed-methods study is being designed for the validation of KIMs and conducted in companies of different sizes and branches in Germany. Workplaces are documented and analysed by observations, applying KIMs, interviews and assessment of environmental conditions. Furthermore, a survey among the employees at the respective workplaces takes place with standardised questionnaires, interviews and physical examinations. It is intended to include 1200 employees at 120 different workplaces. For analysis of the quality criteria, recommendations of the COSMIN checklist (COnsensus-based Standards for the selection of health Measurement INstruments) will be taken into account. The study was planned and conducted in accordance with the German Medical Professional Code and the Declaration of Helsinki as well as the German Federal Data Protection Act. The design of the study was approved by ethics committees. We intend to publish the validated KIMs in 2018. Results will be published in peer-reviewed journals, presented at international meetings and disseminated to actual users for practical application. © Article

  18. Uptake of a Dashboard Designed to Give Realtime Feedback to a Sentinel Network About Key Data Required for Influenza Vaccine Effectiveness Studies.

    Science.gov (United States)

    Pathirannehelage, Sameera; Kumarapeli, Pushpa; Byford, Rachel; Yonova, Ivelina; Ferreira, Filipa; de Lusignan, Simon

    2018-01-01

    Dashboards are technologies that bringing together a range of data sources for observational or analytical purposes. We have created a customised dashboard that includes all the key data elements required for monitoring flu vaccine effectiveness (FVE). This delivers a unique dashboard for each primary care provider (general practice) providing data to the Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC), one of the oldest European surveillance systems. These FVE studies use a test negative case control (TNCC) design. TNCC requires knowledge of practice denominator; vaccine exposure, and results of influenza virology swabs carried out to identify in an influenza-like-illness (ILI), a clinical diagnosis, really is influenza. The dashboard displays the denominator uploaded each week into the surveillance system, compared with the nationally known practice size (providing face-validity for the denominator); it identifies those exposed to the vaccine (by age group and risk category) and virology specimens taken and missed opportunities for surveillance (again by category). All sentinel practices can access in near real time (4 working days in areas) their rates of vaccine exposure and swabs conducted. Initial feedback is positive; 80% (32/40) practices responded positively.

  19. Key issues

    International Nuclear Information System (INIS)

    Cook, N.G.W.

    1980-01-01

    Successful modeling of the thermo-mechanical and hydrochemical behavior of radioactive waste repositories in hard rock is possible in principle. Because such predictions lie outside the realm of experience, their adequacy depends entirely upon a thorough understanding of three fundamental questions: an understanding of the chemical and physical processess that determine the behavior of rock and all its complexities; accurate and realistic numerical models of the geologic media within which a repository may be built; and sufficient in-situ data covering the entire geologic region affected by, or effecting the behavior of a repository. At present sufficient is known to be able to identify most of those areas which require further attention. These areas extend all the way from a complete understanding of the chemical and physical processes determining the behavior of rock through to the exploration mapping and testing that must be done during the development of any potential repository. Many of the techniques, laboratory equipment, field instrumentation, and numerical methods needed to accomplish this do not exist at present. Therefore it is necessary to accept that a major investment in scientific research is required to generate this information over the next few years. The spectrum of scientific and engineering activities is wide extending from laboratory measurements through the development of numerical models to the measurement of data in-situ, but there is every prospect that sufficient can be done to resolve these key issues. However, to do so requires overt recognition of the many gaps which exist in our knowledge and abilities today, and of the need to bridge these gaps and of the significant costs involved in doing so

  20. Design criteria for the electrical system in advanced passive reactors. Special features of the AP-600 Reactor

    International Nuclear Information System (INIS)

    Moraleda Lopez, A.

    1997-01-01

    The design of the electrical system of an Passive Advanced Reactor is determined by the concept of passive actuation of safety systems, simplification of process systems and optimisation of equipment performance. The system that results from these criteria is very different to those designed for present plants. The main differences are: No class 1E alternating current systems No emergency diesel generators Fewer safety and non-safety class electricity consumers System for continuous monitoring of battery status Use of electronic speed regulators for reactor feedwater pump motors Outsite battery backup safety power supply Motor-operated valves are the only safety electrical actuators Portable power supply for post 72 hour equipment This paper develops these concepts and applies them to the AP-600 project and describes the electrical system of this type of plant. (Author)