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Sample records for karnofsky performance status

  1. The Zubrod performance status and the Karnofsky index in quality of life evaluation of children with cancer

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    Larissa Helena Vitoriano Polo

    2009-09-01

    Full Text Available Objective: To describe the epidemiologic profile of children undergoingchemotherapy and/or radiotherapy and to assess the quality of lifeduring treatments, by means of the ECOG scale and the Karnofskyindex. Methods: A descriptive exploratory study, with quantitativeapproach. The sample consisted of children with cancer undergoingchemotherapy or radiotherapy. Results: Twenty-four children, mostmales (67%, were interviewed; chemotherapy was the primarytreatment in 56% of them. The most frequent condition was acutelymphoid leukemia in both sexes. Chemotherapy was the treatmentmodality interfering most with the quality of life, altering aspectssuch as: socialization, behavior, nutrition, sleep and rest, performanceof activities. Regarding the ECOG scale, 75% of the patients whoscored 1 were symptomatic, and only 25% of patients scored 0 andwere asymptomatic. As to the Karnofsky index, 25% of patients wereasymptomatic and performed their daily activities, whereas 71%presented with mild symptoms of the disease, yet performed theirdaily activities. Conclusion: A chronic disease, like cancer, changessome aspects in the daily routine of the children and their family.However, individual characteristics must be respected aiming at thechild’s quality of life.

  2. Effectiveness of maximal safe resection for glioblastoma including elderly and low karnofsky performance status patients. Retrospective review at a single institute

    International Nuclear Information System (INIS)

    Uzuka, Takeo; Takahashi, Hideaki; Aoki, Hiroshi; Natsumeda, Manabu; Fujii, Yukihiko

    2012-01-01

    Elderly and low Karnofsky performance status (KPS) patients have been excluded from most prospective trials. This retrospective study investigated glioblastoma treatment outcomes, including those of elderly and low KPS patients, and analyzed the prognostic factors using the medical records of 107 consecutive patients, 59 men and 48 women aged from 21 to 85 years (median 65 years), with newly diagnosed glioblastoma treated at our institute. There were 71 high-risk patients with age >70 years and/or KPS 6 -methylguanine-deoxyribonucleic acid methyltransferase-negative (p=0.027), and more than subtotal removal (p=0.003) were significant prognostic factors. The median postoperative KPS score tended to be better than the preoperative score, even in the high-risk group. We recommend maximal safe resection for glioblastoma patients, even those with advanced age and/or with low KPS scores. (author)

  3. Karnofsky Performance Status and Lactate Dehydrogenase Predict the Benefit of Palliative Whole-Brain Irradiation in Patients With Advanced Intra- and Extracranial Metastases From Malignant Melanoma

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    Partl, Richard, E-mail: richard.partl@medunigraz.at [Department of Therapeutic Radiology and Oncology, Medical University of Graz, Graz (Austria); Richtig, Erika [Department of Dermatology, Medical University of Graz, Graz (Austria); Avian, Alexander; Berghold, Andrea [Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz (Austria); Kapp, Karin S. [Department of Therapeutic Radiology and Oncology, Medical University of Graz, Graz (Austria)

    2013-03-01

    Purpose: To determine prognostic factors that allow the selection of melanoma patients with advanced intra- and extracerebral metastatic disease for palliative whole-brain radiation therapy (WBRT) or best supportive care. Methods and Materials: This was a retrospective study of 87 patients who underwent palliative WBRT between 1988 and 2009 for progressive or multiple cerebral metastases at presentation. Uni- and multivariate analysis took into account the following patient- and tumor-associated factors: gender and age, Karnofsky performance status (KPS), neurologic symptoms, serum lactate dehydrogenase (LDH) level, number of intracranial metastases, previous resection or stereotactic radiosurgery of brain metastases, number of extracranial metastasis sites, and local recurrences as well as regional lymph node metastases at the time of WBRT. Results: In univariate analysis, KPS, LDH, number of intracranial metastases, and neurologic symptoms had a significant influence on overall survival. In multivariate survival analysis, KPS and LDH remained as significant prognostic factors, with hazard ratios of 3.3 (95% confidence interval [CI] 1.6-6.5) and 2.8 (95% CI 1.6-4.9), respectively. Patients with KPS ≥70 and LDH ≤240 U/L had a median survival of 191 days; patients with KPS ≥70 and LDH >240 U/L, 96 days; patients with KPS <70 and LDH ≤240 U/L, 47 days; and patients with KPS <70 and LDH >240 U/L, only 34 days. Conclusions: Karnofsky performance status and serum LDH values indicate whether patients with advanced intra- and extracranial tumor manifestations are candidates for palliative WBRT or best supportive care.

  4. Assessment of peri- and postoperative complications and Karnofsky-performance status in head and neck cancer patients after radiation or chemoradiation that underwent surgery with regional or free-flap reconstruction for salvage, palliation, or to improve function

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    Sertel Serkan

    2011-09-01

    Full Text Available Abstract Background Surgery after (chemoradiation (RCTX/RTX is felt to be plagued with a high incidence of wound healing complications reported to be as high as 70%. The additional use of vascularized flaps may help to decrease this high rate of complications. Therefore, we examined within a retrospective single-institutional study the peri--and postoperative complications in patients who underwent surgery for salvage, palliation or functional rehabilitation after (chemoradiation with regional and free flaps. As a second study end point the Karnofsky performance status (KPS was determined preoperatively and 3 months postoperatively to assess the impact of such extensive procedures on the overall performance status of this heavily pretreated patient population. Findings 21 patients were treated between 2005 and 2010 in a single institution (17 male, 4 female for salvage (10/21, palliation (4/21, or functional rehabilitation (7/21. Overall 23 flaps were performed of which 8 were free flaps. Major recipient site complications were observed in only 4 pts. (19% (1 postoperative haemorrhage, 1 partial flap loss, 2 fistulas and major donor site complications in 1 pt (wound dehiscence. Also 2 minor donor site complications were observed. The overall complication rate was 33%. There was no free flap loss. Assessment of pre- and postoperative KPS revealed improvement in 13 out of 21 patients (62%. A decline of KPS was noted in only one patient. Conclusions We conclude that within this (chemoradiated patient population surgical interventions for salvage, palliation or improve function can be safely performed once vascularised grafts are used.

  5. Outcome After Radiosurgery for Brain Metastases in Patients With Low Karnofsky Performance Scale (KPS) Scores

    International Nuclear Information System (INIS)

    Chernov, Mikhail F.; Nakaya, Kotaro; Izawa, Masahiro; Hayashi, Motohiro; Usuba, Yuki; Kato, Koichi; Muragaki, Yoshihiro; Iseki, Hiroshi; Hori, Tomokatsu; Takakura, Kintomo

    2007-01-01

    Purpose: The objective of this retrospective study was evaluation of the outcome after stereotactic radiosurgery (SRS) in patients with intracranial metastases and poor performance status. Methods and Materials: Forty consecutive patients with metastatic brain tumors and Karnofsky performance scale (KPS) scores ≤50 (mean, 43 ± 8; median, 40) treated with SRS were analyzed. Poor performance status was caused by presence of intracranial metastases in 28 cases (70%) and resulted from uncontrolled extracerebral disease in 12 (30%). Results: Survival after SRS varied from 3 days to 11.5 months (mean, 3.8 ± 2.9 months; median, 3.3 months). Survival probability constituted 0.50 ± 0.07 at 3 months and 0.20 ± 0.05 at 6 months posttreatment. Cause of low KPS score (p = 0.0173) and presence of distant metastases beside the brain (p = 0.0308) showed statistically significant associations with overall survival in multivariate Cox proportional hazards regression analysis. Median survival was 6.0 months if low KPS score was caused by cerebral disease and distant metastases in regions beyond the brain were absent, 3.3 months if low KPS score was caused by cerebral disease and distant metastases in regions beyond the brain were present, and 1.0 month if poor performance status resulted from extracerebral disease. Conclusions: Identification of the cause of low KPS score (cerebral vs. extracerebral) in patients with metastatic brain tumor(s) may be important for prediction of the outcome after radiosurgical treatment. If poor patient performance status without surgical indications is caused by intracranial tumor(s), SRS may be a reasonable treatment option

  6. Stereotactic Radiosurgery for Poor Performance Status Patients

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    Kubicek, Gregory J., E-mail: kubicek-gregory@cooperhealth.edu [Department of Radiation Oncology, Cooper University Hospital, Camden, New Jersey (United States); Turtz, Alan [Department of Neurological Surgery, Cooper University Hospital, Camden, New Jersey (United States); Xue, Jinyu; Patel, Ashish; Richards, Gregory; LaCouture, Tamara [Department of Radiation Oncology, Cooper University Hospital, Camden, New Jersey (United States); Cappelli, Louis; Diestelkamp, Tim [Rowan Graduate School, Camden, New Jersey (United States); Saraiya, Piya [Department of Diagnostic Radiology, Cooper University Hospital, Camden, New Jersey (United States); Bexon, Anne [Department of Neurological Surgery, Cooper University Hospital, Camden, New Jersey (United States); Lerman, Nati [Department of Medical Oncology, Cooper University Hospital, Camden, New Jersey (United States); Goldman, Howard Warren [Department of Neurological Surgery, Cooper University Hospital, Camden, New Jersey (United States)

    2016-07-01

    Purpose: Patients with poor performance status (PS), usually defined as a Karnofsky Performance Status of 60 or less, were not eligible for randomized stereotactic radiosurgery (SRS) studies, and many guidelines suggest that whole-brain radiation therapy (WBRT) is the most appropriate treatment for poor PS patients. Methods and Materials: In this retrospective review of our SRS database, we identified 36 patients with PS of 60 or less treated with SRS for central nervous system (CNS) metastatic disease. PS, as defined by the Karnofsky Performance Status, was 60 (27 patients), 50 (8 patients), or 40 (1 patient). The median number of CNS lesions treated was 3. Results: Median overall survival (OS) was 7.2 months (range, 0.73-25.6 months). Fifteen patients (41%) were alive at 6 months, and 6 patients (16.6%) were alive at 1 year. There was no difference in OS in patients who underwent previous WBRT. There were no local failures or cases of radiation toxicity. Distant CNS failures were seen in 9 patients (25%). Conclusions: Our patients with poor PS had reasonable median OS and relatively low distant CNS failure rates. Patients in this patient population may be ideal candidates for SRS compared with WBRT given the low incidence of distant failure over their remaining lives and the favorable logistics of single-fraction treatment for these patients with debility and their caregivers.

  7. A phase I/II study of hypofractionated whole abdominal radiation therapy in patients with chemoresistant ovarian carcinoma: Karnofsky score determines treatment outcome

    International Nuclear Information System (INIS)

    Faul, Clare; Gerszten, Kristina; Edwards, Robert; Land, Stephanie; D'Angelo, Gina M.S.; Kelley, Joseph; Price, Fredric

    2000-01-01

    Purpose: Radiation therapy can provide useful palliation in chemorefractory ovarian cancer patients. The purpose of this study was to prospectively study the palliative effect of a hypofractionated radiation treatment regimen. Change in quality-of-life scores (Functional Assessment of Cancer Therapy [FACT], Karnofsky scale), pain score, and tolerance to therapy were also assessed. Methods and Materials: A single-institution Phase I/II trial was initiated in patients with chemoresistant recurrent or progressive ovarian cancer. All patients had symptomatic and measurable intra-abdominal disease. Patients were treated with a single radiation fraction (700 cGy) or two fractions (300 cGy twice a day) to the whole abdomen over 1 day. Quality-of-life scale (FACT G version 2) was assessed at baseline and 1 and 3 months following treatment. Karnofsky scale and pain score were also evaluated in the same time frame. Results: Sixteen patients were prospectively entered into this protocol between February 1996 and September 1998. Twelve patients received a single 700 cGy fraction and four 300 cGy twice a day. All were heavily pretreated and 9 (56%) had a poor performance status prior to treatment. Symptoms needing palliation included pain (14), ascites (10), and bleeding (2). Symptomatic improvement occurred in all patients with pain (5 complete response [CR] and 7 partial response [PR], all patients with bleeding (CR 2), and two (20%) with ascites. Five patients (31%) had a reduction in lesion size documented radiologically in three. The mean duration of response was 22 weeks in patients with a Karnofsky score >70. Thirteen patients developed transient nausea and vomiting which resolved in 48 hours in all. All patients developed a transient lymphopenia. Thirteen patients completed a follow-up quality-of-life scale. There was an improvement in the physical and functional components of the scale in patients with Karnofsky score of 90-100. There was no improvement in quality of

  8. Hypogammaglobulinemia and Poor Performance Status are Predisposing Factors for Vancomycin-Resistant Enterococcus Colonization in Patients with Hematological Malignancies

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    Elif Gülsüm Ümit

    2017-03-01

    Full Text Available Objective: Vancomycin-resistant enterococci (VRE are common pathogens of hospital-acquired infection. Long hospitalization periods, use of broadspectrum antibiotics, and immunosuppression are major risks for VRE colonization. We aimed to evaluate patients’ characteristics and factors that may contribute to VRE colonization. Materials and Methods: Data of 66 patients with colonization and 112 patients without colonization who were hospitalized in the hematology clinic were collected. Hematological malignancies, preexisting gastrointestinal complaints, the presence of hypogammaglobulinemia at the time of diagnosis, complications like neutropenic enterocolitis (NEC, and Eastern Cooperative Oncology Group (ECOG and Karnofsky performance statuses were recorded. Results: Ages of the patients ranged between 19 and 95 years (mean: 55.99. Karnofsky and ECOG scores were statistically related to VRE colonization (p7 days may also be accepted as a risk factor, independent of diagnosis or antibiotic use. Performance status is also an important factor for colonization, which may be related to poorer hygiene and increased external help.

  9. What effects performance status of patients with hepatocellular carcinoma: stage of tumor versus underlying liver status

    International Nuclear Information System (INIS)

    Sarwar, S.; Tarique, S.

    2015-01-01

    Objective: To identify variables associated with poor performance status of hepatocellular carcinoma (HCC) patients and to compare impact of stage of liver disease and that of hepatoma on functional status of patient. Patients and Methods: We included 254 confirmed cases of liver cancer in a crosssectional analytical study carried out at Doctors Hospital Lahore. Patient's clinical, biochemical and radiological variables were correlated with Karnofsky's performance status (KPS) using pearson correlation. Model for End stage Liver Disease (MELD) and Cancer of Liver Italian Program (CLIP) were evaluated for predicting performance status using Receiver Operating Characteristic (ROC) curve. Results: Mean age of patients was 56.69 (±10.34) and male to female ratio was 2.47: 1 (181/73). On KPS evaluation 84 (33.1%) patients scored between 80-100, 147 (57.9%) had score of 50-70 while in 23 (9.1%) KPS score was between 0-40. Variables associated with poor performance status were bilirubin> 3mg/dl (p value 0.00), albumin< 2.5 g/dl (p value 0.00), creatinine > 1.2mg/dl (p 0.00), prothrombin time> 16seconds (p value 0.00), size of tumor >7cm (p value 0.02), tumor involving > 50% of liver mass (p value 0.00) and vascular invasion (p value 0.00). Both stage of liver disease as determined by MELD and stage of liver cancer as per CLIP scores had strong correlation (p value 0.00) with poor performance status of patient. Area under ROC curve was 0.764 for MELD score and 0.785 for CLIP score. Conclusion: Performance status of liver cancer patients is affected by both stage of liver disease and that of liver tumor. Patients with MELD score above 16 and CLIP score above 4 have poor performance status. (author)

  10. Coping style and performance status in a group of oncological inpatients

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    Cecilia Chau Pérez-Aranibar

    2002-06-01

    Full Text Available The associations between coping styles, measured by COPE Test, dispositional version (Carver,Scheier and Weintraub, 1989, and Health Status inferred through a performance status, measured by Karnofsky's Index of Behavioral Performance are examined. The study focuses upon 28 oncological in patients. Positive moderate Pearson's correlations were found between these two variables in this correlational-descriptive study. These were interpreted in the following sense: the larger use of the style, the less health status among the scales suppression of competent activities, procrastination of coping, instrumental social support, focusing and releasing of emotions and behavioral disengagement. The active coping scale presented a negative correlationwith regard to Performance Status as a health measure.

  11. 'Just give me the best quality of life questionnaire': the Karnofsky scale and the history of quality of life measurements in cancer trials.

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    Timmermann, Carsten

    2013-09-01

    To use the history of the Karnofsky Performance Scale as a case study illustrating the emergence of interest in the measurement and standardisation of quality of life; to understand the origins of current-day practices. Articles referring to the Karnofsky scale and quality of life measurements published from the 1940s to the 1990s were identified by searching databases and screening journals, and analysed using close-reading techniques. Secondary literature was consulted to understand the context in which articles were written. The Karnofsky scale was devised for a different purpose than measuring quality of life: as a standardisation device that helped quantify effects of chemotherapeutic agents less easily measurable than survival time. Interest in measuring quality of life only emerged around 1970. When quality of life measurements were increasingly widely discussed in the medical press from the late 1970s onwards, a consensus emerged that the Karnofsky scale was not a very good tool. More sophisticated approaches were developed, but Karnofsky continued to be used. I argue that the scale provided a quick and simple, approximate assessment of the 'soft' effects of treatment by physicians, overlapping but not identical with quality of life.

  12. ‘Just give me the best quality of life questionnaire’: the Karnofsky scale and the history of quality of life measurements in cancer trials

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    Timmermann, Carsten

    2013-01-01

    Objectives: To use the history of the Karnofsky Performance Scale as a case study illustrating the emergence of interest in the measurement and standardisation of quality of life; to understand the origins of current-day practices. Methods: Articles referring to the Karnofsky scale and quality of life measurements published from the 1940s to the 1990s were identified by searching databases and screening journals, and analysed using close-reading techniques. Secondary literature was consulted to understand the context in which articles were written. Results: The Karnofsky scale was devised for a different purpose than measuring quality of life: as a standardisation device that helped quantify effects of chemotherapeutic agents less easily measurable than survival time. Interest in measuring quality of life only emerged around 1970. Discussion: When quality of life measurements were increasingly widely discussed in the medical press from the late 1970s onwards, a consensus emerged that the Karnofsky scale was not a very good tool. More sophisticated approaches were developed, but Karnofsky continued to be used. I argue that the scale provided a quick and simple, approximate assessment of the ‘soft’ effects of treatment by physicians, overlapping but not identical with quality of life. PMID:23239756

  13. Expert status and performance.

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    Mark A Burgman

    Full Text Available Expert judgements are essential when time and resources are stretched or we face novel dilemmas requiring fast solutions. Good advice can save lives and large sums of money. Typically, experts are defined by their qualifications, track record and experience. The social expectation hypothesis argues that more highly regarded and more experienced experts will give better advice. We asked experts to predict how they will perform, and how their peers will perform, on sets of questions. The results indicate that the way experts regard each other is consistent, but unfortunately, ranks are a poor guide to actual performance. Expert advice will be more accurate if technical decisions routinely use broadly-defined expert groups, structured question protocols and feedback.

  14. Effects of preventive versus "on-demand" nutritional support on paid labour productivity, physical exercise and performance status during PEG-interferon-containing treatment for hepatitis C.

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    Huisman, Ellen J; van Meer, Suzanne; van Hoek, Bart; van Soest, Hanneke; van Nieuwkerk, Karin M J; Arends, Joop E; Siersema, Peter D; van Erpecum, Karel J

    2016-04-01

    Deterioration of nutritional status during PEG-interferon containing therapy for chronic hepatitis C can be ameliorated by preventive nutritional support. We aimed to explore whether such support also affects paid labour productivity, physical exercise and performance status. In this prospective randomized controlled trial (J Hepatol 2012;57:1069-75), 53 patients with chronic hepatitis C had been allocated to "on demand" support (n=26: nutritional intervention if weight loss>5%) or preventive support (n=27: regular dietary advice plus energy- and protein-rich evening snack) during PEG-interferon-containing therapy. Paid labour productivity, physical exercise and performance status were evaluated at baseline, after 24 and (if applicable) after 48 weeks of treatment. At baseline, 46% of patients performed paid labour and 62% performed some kind of physical exercise. Furthermore, most patients were able to carry out normal activity with only minor symptoms of disease (mean Karnofsky performance score: 94). Decreases of paid labour productivity (-21% vs. -70%, P=0.003), physical exercise activity (-43% vs. -87%, P=0.005) and Karnofsky performance scores (-12% vs. -24%, Plabour productivity, physical exercise and performance status during PEG-interferon-containing treatment for chronic hepatitis C. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  15. Simple prognostic model for patients with advanced cancer based on performance status.

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    Jang, Raymond W; Caraiscos, Valerie B; Swami, Nadia; Banerjee, Subrata; Mak, Ernie; Kaya, Ebru; Rodin, Gary; Bryson, John; Ridley, Julia Z; Le, Lisa W; Zimmermann, Camilla

    2014-09-01

    Providing survival estimates is important for decision making in oncology care. The purpose of this study was to provide survival estimates for outpatients with advanced cancer, using the Eastern Cooperative Oncology Group (ECOG), Palliative Performance Scale (PPS), and Karnofsky Performance Status (KPS) scales, and to compare their ability to predict survival. ECOG, PPS, and KPS were completed by physicians for each new patient attending the Princess Margaret Cancer Centre outpatient Oncology Palliative Care Clinic (OPCC) from April 2007 to February 2010. Survival analysis was performed using the Kaplan-Meier method. The log-rank test for trend was employed to test for differences in survival curves for each level of performance status (PS), and the concordance index (C-statistic) was used to test the predictive discriminatory ability of each PS measure. Measures were completed for 1,655 patients. PS delineated survival well for all three scales according to the log-rank test for trend (P statistic was similar for all three scales and ranged from 0.63 to 0.64. We present a simple tool that uses PS alone to prognosticate in advanced cancer, and has similar discriminatory ability to more complex models. Copyright © 2014 by American Society of Clinical Oncology.

  16. Quality of life and performance status in patients with pancreatic and periampullary tumors

    International Nuclear Information System (INIS)

    Velanovich, V.; Wollner, I.

    2011-01-01

    The background of this study was to determine if pretreatment quality of life is associated with performance status in patients with pancreatic and periampullary tumors. Eighty consecutive patients evaluated for surgical treatment of pancreatic or periampullary tumors completed the social functioning SF-36, a generic quality of life instrument. This instrument measures 8 domains of quality of life: physical functioning (PF), role-physical (RP), role-emotional, bodily pain, vitality, mental health, social functioning, and general health (GH). The best possible score is 100 and the worst possible score is 0. Each patient was then assigned a Karnofsky performance score (KPS), with the best possible score of 100 (normal, no complaints, no evidence of disease) and worst score of 0 (dead). Data recorded included age, gender, pathology, stage, resection, use of chemotherapy, and radiation therapy. Statistical analysis was done using single and multiple linear regression analysis, correlation coefficients (r) and coefficient of determination (r 2 ). KPS was significantly associated with all domains of the SF-36 by single linear regression. By multiple linear regression, KPS was significantly associated with the PF domain (p 2 values) suggest that there are additional factors determining both quality of life and performance status in patients with pancreatic and periampullary tumors. (author)

  17. Avaliação da capacidade física e do estado nutricional em candidatos ao transplante hepático Evaluation of the nutritional status and physical performance in candidates to liver transplantation

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    Ana V. A. Leitão

    2003-01-01

    found in 32% of the patients. Impaired balance and coordination were detected in 34.8% and 15.6% of the patients. Low physical performance was found in 72.5% of the patients (6min walk test: 31.6% severely; 40.9% moderately impaired and 43.8% required considerable assistance when the Karnofsky index was applied. Malnutrition was found in 62.5% of the patients (34.37% moderately and severely malnourished and 28.13% mildly malnourished. Chi-square analysis showed no association between Child-Pugh classification and nutritional status, the 6min walk test and Karnofsky index. The association between the two functional tests was statistically significant (p<0.001. CONCLUSION: The results show that physical impairment and nutritional deficit were highly prevalent in the patients studied, independent of the degree of hepatic dysfunction evaluated by the traditional Child-Pugh classification.

  18. Status and performance of PF injector linac

    International Nuclear Information System (INIS)

    Sato, Isamu

    1994-01-01

    PF injector linac has been improved on a buncher section for accelerating of intense electron beam, and reinforced a focusing system of the positron generator linac for the expansion of phase space. In this presentation, I shall report present status and performance of PF injector linac, and discuss its upgrade program for B-factory project. (author)

  19. Mild Cognitive Impairment Status and Mobility Performance

    DEFF Research Database (Denmark)

    Pedersen, Mette; Holt, Nicole E; Grande, Laura

    2014-01-01

    : An analysis was conducted on baseline data from the Boston Rehabilitative Impairment Study in the Elderly study, a cohort study of 430 primary care patients aged 65 or older. Neuropsychological tests identified participants with MCI and further subclassified those with impairment in memory domains (a......BACKGROUND: The prevalence of mild cognitive impairment (MCI) and mobility limitations is high among older adults. The aim of this study was to investigate the association between MCI status and both performance-based and self-report measures of mobility in community-dwelling older adults. METHODS...

  20. Improvement in performance status after erythropoietin treatment in lung cancer patients undergoing concurrent chemoradiotherapy

    International Nuclear Information System (INIS)

    Casas, Francesc; Vinolas, Nuria; Ferrer, Ferran; Farrus, Blanca; Gimferrer, Josep Maria; Agusti, Carles; Belda, Josep; Luburich, Patricio

    2003-01-01

    Purpose: A prospective Phase II trial was carried out to evaluate the effectiveness of erythropoietin in improving or maintaining performance status as determined by the Karnofsky performance status (KPS) score and hemoglobin (Hb) levels in lung cancer patients treated with concurrent chemoradiation (CH-RT). Methods and Materials: A total of 51 patients with lung cancer (11 with small-cell, limited stage and 40 with non-small-cell disease, 17 with Stage IIIA and 23 with Stage IIIB), who underwent three different concurrent CH-RT protocols were enrolled. Baseline Hb and KPS values were recorded, as were the nadir Hb and KPS values before concurrent CH-RT. The final Hb and KPS values were recorded the last week of concurrent CH-RT. An Hb level of ≤11 g/dL before concurrent CH-RT was required before receiving erythropoietin. Prognostic factors for KPS improvement and survival were assessed by univariate and multivariate studies. Results: Of the 51 patients, 47 (92.3%) were men (mean age 63.6 years, range 40-75). The median baseline KPS score was 80, and the mean baseline Hb was 12.2 ± 1.76 g/dL (range 9-16.9). The mean nadir and final Hb value was 9.98±0.67 g/dL (range 8.6-11) and 11.33±1.59 g/dL (range 6.9-14.4), respectively. A significant increase was seen in the Hb and KPS score (p<0.05) in the final measurements. Differences were found between the final and nadir Hb in the predictive value for differences in performance status (p=0.001). On univariate study, pathologic findings (p=0.0234), weight loss (p=0.0049), baseline Hb (p=0.0057), and final Hb improvement (p=0.0237) were prognostic factors for survival. Nadir Hb (p=0.027), final Hb improvement (p=0.0069), pathologic findings (p = 0.0006), and weight loss (p=0.0001) had significant prognostic value for survival in multivariate analysis. Conclusion: In this study, erythropoietin appears to have a significant, beneficial impact on the KPS and Hb of patients undergoing concurrent CH-RT

  1. Block Storage Service: Status and Performance

    CERN Document Server

    Van der Ster, Daniel

    2014-01-01

    This memo summarizes the current status of the Ceph block storage service as it is used for OpenStack Cinder Volumes and Glance Images as of May 2014. We present the block storage activity on the current cluster, measuring IOPS and latencies, and present a cost/benefit analysis of using SSDs to optimize the cost and performance efficiency of the service. During tests in collaboration with IT-CF, we have concluded that by adding SSDs as the synchronous write journals (used to guarantee data durability), we are able increase the IOPS capacity by 4-5 times, at a cost of decreasing the available volume by 20%. Further, the testing has shown that the Ceph implementation is able to operate at the limit of the hardware performance; software-induced performance limitations were not yet observed in either the spinning disk or SSD configurations. In addition, we believe that increasing small write performance with SSDs is applicable only to the block storage use-case; high-bandwidth use-cases such as physics data stora...

  2. ACCESS: Thermal Mechanical Design, Performance, and Status

    Science.gov (United States)

    Kaiser, Mary Elizabeth; Morris, M. J.; McCandliss, S. R.; Rauscher, B. J.; Kimble, R. A.; Kruk, J. W.; Wright, E. L.; Bohlin, R.; Kurucz, R. L.; Riess, A. G.; Pelton, R.; Deustua, S. E.; Dixon, W. V.; Sahnow, D. J.; Benford, D. J.; Gardner, J. P.; Feldman, P. D.; Moos, H. W.; Lampton, M.; Perlmutter, S.; Woodgate, B. E.

    2014-01-01

    Systematic errors associated with astrophysical data used to probe fundamental astrophysical questions, such as SNeIa observations used to constrain dark energy theories, are now rivaling and exceeding the statistical errors associated with these measurements. ACCESS: Absolute Color Calibration Experiment for Standard Stars is a series of rocket-borne sub-orbital missions and ground-based experiments designed to enable improvements in the precision of the astrophysical flux scale through the transfer of absolute laboratory detector standards from the National Institute of Standards and Technology (NIST) to a network of stellar standards with a calibration accuracy of 1% and a spectral resolving power of 500 across the 0.35 - 1.7μm bandpass. Achieving this level of accuracy requires characterization and stability of the instrument and detector including a thermal background that contributes less than 1% to the flux per resolution element in the NIR. We will present the instrument and calibration status with a focus on the thermal mechanical design and associated performance data. The detector control and performance will be presented in a companion poster (Morris, et al). NASA APRA sounding rocket grant NNX08AI65G supports this work.

  3. Status and Performance of University Librarians in Uganda ...

    African Journals Online (AJOL)

    It was also found that the status of university librarians is a significant predictor of their performance. Therefore, the paper urges university administrators in the country to re-examine the status accorded to their librarians because it is an important ingredient in their performance. Keywords: Library management; Performance ...

  4. Nutritional status of cancer patients admitted for chemotherapy at the National Kidney and Transplant Institute.

    Science.gov (United States)

    Montoya, J E; Domingo, F; Luna, C A; Berroya, R M; Catli, C A; Ginete, J K; Sanchez, O S; Juat, N J; Tiangco, B J; Jamias, J D

    2010-11-01

    Malnutrition is common among cancer patients. This study aimed to determine the overall prevalence of malnutrition among patients undergoing chemotherapy and to determine the predictors of malnutrition among cancer patients. A cross-sectional study was conducted on 88 cancer patients admitted for chemotherapy at the National Kidney and Transplant Institute, Philippines, from October to November 2009. Subjective Global Assessment (SGA), anthropometric data and demographic variables were obtained. Descriptive statistics, ANOVA and logistic regression analysis were performed between the outcome and variables. A total of 88 cancer patients were included in the study. The mean age of the patients was 55.7 +/- 14.8 years. The mean duration of illness was 9.7 +/- 8.7 months and the mean body mass index (BMI) was 22.9 kg/m2. The mean Karnofsky performance status was 79.3. 29.55 percent of the patients had breast cancer as the aetiology of their illness. 38 patients (43.2 percent) had SGA B and four (4.5 percent) had SGA C, giving a total malnutrition prevalence of 47.7 percent. The patients were statistically different with regard to their cancer stage (p is less than 0.001), weight (p is 0.01), BMI (p is 0.004), haemoglobin level (p is 0.001) and performance status by Karnofsky score (p is less than 0.001), as evaluated by ANOVA. Logistic regression analysis showed that cancer stage and Karnofsky performance score were predictors of malnutrition. About 47.7 percent of cancer patients suffer from malnutrition, as classified by SGA. Only cancer stage and Karnofsky performance status scoring were predictive of malnutrition in this select group of patients.

  5. Trajectories of Symptom Clusters, Performance Status, and Quality of Life During Concurrent Chemoradiotherapy in Patients With High-Grade Brain Cancers.

    Science.gov (United States)

    Kim, Sang-Hee; Byun, Youngsoon

    Symptom clusters must be identified in patients with high-grade brain cancers for effective symptom management during cancer-related therapy. The aims of this study were to identify symptom clusters in patients with high-grade brain cancers and to determine the relationship of each cluster with the performance status and quality of life (QOL) during concurrent chemoradiotherapy (CCRT). Symptoms were assessed using the Memorial Symptom Assessment Scale, and the performance status was evaluated using the Karnofsky Performance Scale. Quality of life was assessed using the Functional Assessment of Cancer Therapy-General. This prospective longitudinal survey was conducted before CCRT and at 2 to 3 weeks and 4 to 6 weeks after the initiation of CCRT. A total of 51 patients with newly diagnosed primary malignant brain cancer were included. Six symptom clusters were identified, and 2 symptom clusters were present at each time point (ie, "negative emotion" and "neurocognitive" clusters before CCRT, "negative emotion and decreased vitality" and "gastrointestinal and decreased sensory" clusters at 2-3 weeks, and "body image and decreased vitality" and "gastrointestinal" clusters at 4-6 weeks). The symptom clusters at each time point demonstrated a significant relationship with the performance status or QOL. Differences were observed in symptom clusters in patients with high-grade brain cancers during CCRT. In addition, the symptom clusters were correlated with the performance status and QOL of patients, and these effects could change during CCRT. The results of this study will provide suggestions for interventions to treat or prevent symptom clusters in patients with high-grade brain cancer during CCRT.

  6. Cassini radar: Instrument description and performance status

    Science.gov (United States)

    Johnson, W. T. K.; Im, E.; Borgarelli, L.; ZampoliniFaustini, E.

    1995-01-01

    The spacecraft of the Cassini mission is planned to be launched towards Saturn in October 1997. The mission is designed to study the physical structure and chemical composition of Titan. The results of the tests performed on the Cassini radar engineering qualification model (EQM) are summarized. The approach followed in the verification and evaluation of the performance of the radio frequency subsystem EQM is presented. The results show that the instrument satisfies the most relevant mission requirements.

  7. Nuclear power plant performance. Status and trends

    International Nuclear Information System (INIS)

    Glorian, D.

    1995-01-01

    The performance of nuclear power plants can be assessed in several different fields: operating costs, safety, reliability of electricity generation, impact on the environment and personnel protection (industrial safety, radiation protection, etc.). Comparing national and international performance levels involves the use of performance indicators, together with a terminology, precise definitions and computerized data collection and processing facilities. The paper gives a brief review of the different actions undertaken during the last ten years to achieve international harmonization in the use of indicators. The main international indicators in use today by virtually all nuclear operators around the world are examined. Figures are given for each of these main indicators. In particularly, the levels of 'excellence' achieved throughout the world are discussed, together with the difficulties encountered in trying to match them or indeed maintain them. Future prospects regarding both the efforts made towards achieving international harmonization and the optimum use of this system of international performance indicators are examined, in order to achieve mutual enhancement through this approach to feedback of experience. Considering the overall performance indicators in use, it must be clearly recognized that, over the last ten years, the nuclear industry has made a tremendous effort to improve performance; the challenge for the future is to maintain a very high level of quality in the area of safety by keeping the operating costs (and investment costs for future plants) within a reasonable range

  8. The national ignition facility performance status

    Energy Technology Data Exchange (ETDEWEB)

    Haynam, C.; Auerbach, J.; Bowers, M.; Di-Nicola, J.M.; Dixit, S.; Erbert, G.; Heestand, G.; Henesian, M.; Jancaitis, K.; Manes, K.; Marshall, C.; Mehta, N.; Nostrand, M.; Orth, C.; Sacks, R.; Shaw, M.; Sutton, S.; Wegner, P.; Williams, W.; Widmayer, C.; White, R.; Yang, S.; Van Wonterghem, B. [Lawrence Livermore National Laboratory, Livermore, CA (United States)

    2006-06-15

    The National Ignition Facility (NIF) laser has been designed to support high energy density science, including the demonstration of fusion ignition through Inertial Confinement. NIF operated a single 'quad' of 4 beams from December 2002 through October 2004 in order to gain laser operations experience, support target experiments, and demonstrate laser performance consistent with NIF's design requirement. During this two-year period, over 400 Main Laser shots were delivered at 1{omega} to calorimeters for diagnostic calibration purposes, at 3{omega} to the Target Chamber, and at 1{omega}, 2{omega}, and 3{omega} to the precision diagnostic system (PDS). The PDS includes its own independent single beam transport system, NIF design frequency conversion hardware and optics, and laser sampling optics that deliver light to a broad range of laser diagnostics. Highlights of NIF laser performance will be discussed including the results of high energy 2{omega} and 3{omega} experiments, the use of multiple focal spot beam conditioning techniques, the reproducibility of laser performance on multiple shots, the generation on a single beam of a 3{omega} temporally shaped ignition pulse at full energy and power, and recent results on full bundle (8 beamline) performance. NIF's first quad laser performance meets or exceeds NIF's design requirements. (authors)

  9. The National Ignition Facility Performance Status

    Energy Technology Data Exchange (ETDEWEB)

    Haynam, C; Auerbach, J; Nicola, J D; Dixit, S; Heestand, G; Henesian, M; Jancaitis, K; Manes, K; Marshall, C; Mehta, N; Nostrand, M; Orth, C; Sacks, R; Shaw, M; Sutton, S; Wegner, P; Williams, W; Widmayer, C; White, R; Yang, S; Van Wonterghem, B

    2005-08-30

    The National Ignition Facility (NIF) laser has been designed to support high energy density science (HEDS), including the demonstration of fusion ignition through Inertial Confinement. NIF operated a single ''quad'' of 4 beams from December 2002 through October 2004 in order to gain laser operations experience, support target experiments, and demonstrate laser performance consistent with NIF's design requirement. During this two-year period, over 400 Main Laser shots were delivered at 1{omega} to calorimeters for diagnostic calibration purposes, at 3{omega} to the Target Chamber, and at 1{omega}, 2{omega}, and 3{omega} to the Precision Diagnostics System (PDS). The PDS includes its own independent single beam transport system, NIF design frequency conversion hardware and optics, and laser sampling optics that deliver light to a broad range of laser diagnostics. Highlights of NIF laser performance will be discussed including the results of high energy 2{omega} and 3{omega} experiments, the use of multiple focal spot beam conditioning techniques, the reproducibility of laser performance on multiple shots, the generation on a single beam of a 3{omega} temporally shaped ignition pulse at full energy and power, and recent results on full bundle (8 beamline) performance. NIF's first quad laser performance meets or exceeds NIF's design requirements.

  10. The status of performance demonstration in Taiwan

    International Nuclear Information System (INIS)

    Shyu, H.F.; Shong, W.J.

    2004-01-01

    The nuclear authority in Taiwan adopts the ASME Code Section XI, Appendix VIII as a mandatory requirement for the in-service inspection of importance nuclear components. To fulfill this requirement, the ultrasonic testing (UT) Level II of nuclear power plants have to go abroad for the qualification of performance demonstration (PD) hosted by the EPRI, USA. It is time consuming and costs much money. In order to set up domestic PD capability, this project planned and purchased test pieces, prepared qualification procedures and arranged examination site. A prototype PD system for carbon steel piping weld and stainless steel piping weld manual UT has been established from 2002. Until January 2004, five PD qualification sections have been held. The detection accuracy and uncertainty of flaw length sizing of UT were calculated according to the data provided by the examinees. Based on the available data, the flaw detection accuracy was about 89% for both stainless steel and carbon steel. However, the uncertainty of flaw length sizing varied with test piece material and flaw orientation. This analysis can be a reference for related organizations to gain more insight information of UT results. (author)

  11. Growth performance, immune status and organ morphometry in ...

    African Journals Online (AJOL)

    Growth performance, immune status and organ morphometry in broilers fed Bacillus subtilis -supplemented diet. ... In conclusion, B. subtilis-type probiotics contributed positively to better growth performance, improved immune system and modulated morphology of lymphoid organs and gut mucosa in broilers. Keywords: ...

  12. Effects of nutritional and psychological status of the patients with advanced stomach cancer on physical performance status.

    Science.gov (United States)

    Tian, Jun; Chen, Zhen-chun; Hang, Li-Fang

    2009-10-01

    The aim of this study was to assess the associations between coping mode, nutritional status, and psychological status and performance status of the patients with advanced stomach cancer. An epidemiological survey was conducted among 233 patients with advanced stomach cancer in Fujian, China. In-person interviews were performed for the participants with respect to information of psychological status prior to chemotherapy, nutritional status during chemotherapy, and physical performance status after chemotherapy. Multivariate logistic regression analyses showed that the level of hemoglobin (HB), level of daily calorie intake, score of Depression Status Inventory (DSI), and score of confrontation subscale of Medical Coping Modes Questionnaire had a significant influence on performance status (P or =40 versus DSI score confrontation versus high score of confrontation, respectively. Depression, low score of "Confrontation", low levels of HB, and low level of daily calorie intake may be the risk factors of poor performance status of the patients with advanced stomach cancer.

  13. the relationship of birth status and early reproductive performance ...

    African Journals Online (AJOL)

    The effectiveness of selection for improvement in reproductive performance of sheep depends on measure- ment at any early age. For this reason selection of rams and ewes on their birth status, (single or twin), (Kennedy,. 1967; Turner, Hayman, Triffitt and Prunster, 1969), and ewes having multiple births during their first or ...

  14. Nutritional Status and Cognitive Performance among Children Aged ...

    African Journals Online (AJOL)

    Without adequate nutrition, children cannot develop to their full physical and mental potentials. The nutritional status and the cognitive performance of 500 school children aged 5-12 years from urban and rural areas of Enugu State, Nigeria were evaluated. Anthropometric measurements of heights and weights were ...

  15. Changes in performance status of elderly patients after radiotherapy

    International Nuclear Information System (INIS)

    Yamazaki, Hideya; Inoue, Takehiro; Yoshida, Ken

    2001-01-01

    The purpose of this study was to examine the feasibility of external radiation therapy for patients 80 years old and older. We analyzed changes in the performance status (PS) of 1353 patients by external radiotherapy at Osaka Teishin Hospital. In addition, factors influencing PS change and interruption of treatment were assessed in patients undergoing radical and palliative radiotherapy. Among elderly patients aged 80 years or more (n=67), two patients showed deterioration in PS (3%), whereas 128 (10%) did so among those 79 years old or younger. The rate of treatment completion was 90% (60/67) for patients aged 80 years and over compared with 89% (1146/1286) for younger patients. Changes in PS were more frequent for palliative treatment (improvement 83/683, 12%; deterioration 77/683, 11%) than for radical treatment (improvement 12/305, 4%:, deterioration 21/305, 7%) because patients with better performance status and early disease stages underwent radical treatment. For radical radiotherapy, patients with advanced disease (stages III and IV) showed more changes (improvement 4/108, 4%; deterioration 17/108, 16%) than those with early ones (stages I and II) (improvement 7/132, 5%; deterioration 3/132, 2%) (p<0.01). Better treatment results showed a higher treatment completion rate (CR 99%, PR 86%) than poor treatment results (NC 75%, PD 50%) (p<0.01). For palliative therapy, better performance status (PS 0-2) showed a better correlation with completion of treatment (403/451 or 89%) than did poor performance status (PS 3-4) (174/232, 75%) (p<0.01). Age is not a limiting factor for external radiation therapy. Poor performance status is a significant predisposing factor for interruption of palliative radiotherapy. (author)

  16. Nutritional status assessment in colorectal cancer patients qualified to systemic treatment

    Directory of Open Access Journals (Sweden)

    Monika Ziętarska

    2017-06-01

    Full Text Available Aim of the study . Cancer is usually associated with impaired nutritional status, which is one of the factors contributing to the deterioration of the results of surgery, chemotherapy, or radiotherapy. The aim of this study was the assessment of the nutritional status of patients with CRC qualified to chemotherapy. Material and methods : Seventy-five persons aged 40–86 years with colorectal cancer were examined. To evaluate the nutritional status NRS 2002, SGA, SCRINIO Working Group classification, VAS scale for appetite, and FAACT questionnaire were used. The health status of patients was evaluated based on the Karnofsky Performance Scale. Anthropometric measurements were made. Results : The results indicate that 75% of patients present pre-cachexia status based on SCRINIO Working Group classification. According to both NRS-2002 and SGA, 73.3% of patients were moderately malnourished and 2.7% were severely malnourished. 37.0% of patients had moderate appetite and 6.0% (n = 5 had poor appetite. The Karnofsky score indicates the state of normal activity, and minor signs and symptoms of the disease among most of the patients. A statistically significant positive correlation was found between the VAS and the Karnofsky score (R = 0,4; p < 0.05. The FACCT average score (78.5 indicates a reduction in the quality of life of the patients in all aspects of functioning. Conclusions : Evaluation of the baseline nutritional status of patients with CRC should be a part of routine clinical practice. Because of the high incidence of confirmed pre-cachexia, this group of patients also requires early adequate nutrition intervention.

  17. STATUS OF THE ATLAS LIQUID ARGON CALORIMETER AND ITS PERFORMANCE

    CERN Document Server

    Berillari, T; The ATLAS collaboration

    2011-01-01

    The liquid argon (LAr) calorimeters are used in ATLAS for all electromagnetic and for hadron calorimetry. The LAr calorimeter system consists of an electromagnetic barrel calorimeter and two endcaps with electromagnetic, hadronic and forward calorimeters. The latest status of the detector as well as problems and solutions addressed during the last years will be presented. Aspects of operation of a large detector over a long time period will be summarized and selected topics showing the performance of the detector will be shown.

  18. Delivery strategies to optimize resource utilization and performance status for patients with advanced life-limiting illness: results from the "palliative care trial" [ISRCTN 81117481].

    Science.gov (United States)

    Abernethy, Amy P; Currow, David C; Shelby-James, Tania; Rowett, Debra; May, Frank; Samsa, Gregory P; Hunt, Roger; Williams, Helena; Esterman, Adrian; Phillips, Paddy A

    2013-03-01

    Evidence-based approaches are needed to improve the delivery of specialized palliative care. The aim of this trial was to improve on current models of service provision. This 2×2×2 factorial cluster randomized controlled trial was conducted at an Australian community-based palliative care service, allowing three simultaneous comparative effectiveness studies. Participating patients were newly referred adults, experiencing pain, and who were expected to live >48 hours. Patients enrolled with their general practitioners (GPs) and were randomized three times: 1) individualized interdisciplinary case conference including their GP vs. control, 2) educational outreach visiting for GPs about pain management vs. control, and 3) structured educational visiting for patients/caregivers about pain management vs. control. The control condition was current palliative care. Outcomes included Australia-modified Karnofsky Performance Status (AKPS) and pain from 60 days after randomization and hospitalizations. There were 461 participants: mean age 71 years, 50% male, 91% with cancer, median survival 179 days, and median baseline AKPS 60. Only 47% of individuals randomized to the case conferencing intervention received it; based on a priori-defined analyses, 32% of participants were included in final analyses. Case conferencing reduced hospitalizations by 26% (least squares means hospitalizations per patient: case conference 1.26 [SE 0.10] vs. control 1.70 [SE 0.13], P=0.0069) and better maintained performance status (AKPS case conferences 57.3 [SE 1.5] vs. control 51.7 [SE 2.3], P=0.0368). Among patients with declining function (AKPS performance status (AKPS case conferences 55.0 [SE 2.1] vs. control 46.5 [SE 2.9], P=0.0143; patient/caregiver education 54.7 [SE 2.8] vs. control 46.8 [SE 2.1], P=0.0206). Pain was unchanged. GP education did not change outcomes. A single case conference added to current specialized community-based palliative care reduced hospitalizations and better

  19. Comorbidity and performance status in acute myeloid leukemia patients

    DEFF Research Database (Denmark)

    Ostgård, L S G; Nørgaard, J M; Sengeløv, H

    2015-01-01

    As the world population ages, the comorbidity burden in acute myeloid leukemia (AML) patients increases. Evidence on how to integrate comorbidity measures into clinical decision-making is sparse. We determined the prognostic impact of comorbidity and World Health Organization Performance Status (PS...... with an increased short- and long-term mortality (adjusted 90 day MR, PS⩾2=3.43 (95%CI=2.30-5.13); adjusted 91 day-3 year MR=1.35 (95%CI=1.06-1.74)). We propose that more patients with comorbidity may benefit from intensive chemotherapy.Leukemia advance online publication, 2 September 2014; doi:10.1038/leu.2014.234....

  20. Status, performance and scientific highlights from the MAGIC telescope system

    Energy Technology Data Exchange (ETDEWEB)

    Doert, Marlene [Technische Universitaet Dortmund (Germany); Ruhr-Universitaet Bochum (Germany); Collaboration: MAGIC-Collaboration

    2015-07-01

    The MAGIC telescopes are a system of two 17 m Imaging Air Cherenkov Telescopes, which are located at 2200 m above sea level at the Roque de Los Muchachos Observatory on the Canary Island of La Palma. In this presentation, we report on recent scientific highlights gained from MAGIC observations in the galactic and the extragalactic regime. We also present the current status and performance of the MAGIC system after major hardware upgrades in the years 2011 to 2014 and give an overview of future plans.

  1. The ATLAS liquid argon calorimeter--status and expected performance

    International Nuclear Information System (INIS)

    Schacht, Peter

    2004-01-01

    For the ATLAS detector at the LHC, the liquid argon technique is exploited for the electromagnetic calorimetry in the central part and for the electromagnetic and hadronic calorimetry in the forward and backward regions. The construction of the calorimeter is well advanced with full cold tests of the barrel calorimeter and first endcap calorimeter only months away. The status of the project is discussed as well as the related results from beam test studies of the various calorimeter subdetectors. The results show that the expected performance meets the ATLAS requirements as specified in the ATLAS Technical Design Report

  2. Physical performance in relation to menopause status and physical activity.

    Science.gov (United States)

    Bondarev, Dmitriy; Laakkonen, Eija K; Finni, Taija; Kokko, Katja; Kujala, Urho M; Aukee, Pauliina; Kovanen, Vuokko; Sipilä, Sarianna

    2018-05-21

    The aim of this study was to examine differences in physical performance (muscle power, muscle strength, aerobic capacity, and walking speed) across menopausal stages and potential of leisure physical activity (PA) to modify the impact of menopause on physical performance. In this cross-sectional study, women aged 47 to 55 were randomly selected from the Finnish National Registry and categorized as premenopausal (n = 233), perimenopausal (n = 381), or postmenopausal (n = 299) based on serum concentrations of follicle-stimulating hormone and bleeding diary. Physical performance was measured by knee extension force, handgrip force, vertical jumping height, maximal walking speed, and 6-minute walking distance. PA level was assessed by self-report and categorized as low, moderate, or high. Multivariate linear regression modeling was used for data analysis. After including fat mass, height, PA, and education in the model, the postmenopausal women showed 12.0 N weaker (P women. There was no significant interaction between menopausal stage and PA on physical performance. The peri- and postmenopausal women with a high PA, however, showed better performance in the maximal knee extension strength and 6-minute walking test, and showed greater lower body muscle power than those with a low PA. Menopause status is associated with muscle strength and power, whereas the association between menopause status and mobility/walking is clearly weaker. A high leisure PA level provides more capacity to counteract the potential negative influence of menopausal factors on muscle function.This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0.

  3. Evaluation of Performance Status and Hematopoietic Cell Transplantation Specific Comorbidity Index on Unplanned Admission Rates in Patients with Multiple Myeloma Undergoing Outpatient Autologous Stem Cell Transplantation.

    Science.gov (United States)

    Obiozor, Cynthia; Subramaniam, Dipti P; Divine, Clint; Shune, Leyla; Singh, Anurag K; Lin, Tara L; Abhyankar, Sunil; Chen, G John; McGuirk, Joseph; Ganguly, Siddhartha

    2017-10-01

    Although outpatient autologous stem cell transplantation (ASCT) is safe and feasible in most instances, some patients undergoing planned outpatient transplantation for multiple myeloma (MM) will need inpatient admission for transplantation-related complications. We aim to evaluate the difference, if any, between outpatient and inpatient ASCT cohorts of MM patients in terms of admission rate, transplantation outcome, and overall survival. We also plan to assess whether the Hematopoietic Cell Transplantation Comorbidity Index (HCT-CI) and Karnofsky Performance Status (KPS) can predict unplanned admissions after adjusting for confounding factors. Patients with MM (n = 448) who underwent transplantation at our institution between 2009 and 2014 were included in this retrospective analysis. Patients were grouped into 3 cohorts: cohort A, planned inpatient ASCT (n = 216); cohort B, unplanned inpatient admissions (n = 57); and cohort C, planned outpatient SCT (n = 175). The statistical approach included descriptive, bivariate, and survival analyses. There were no differences among the 3 cohorts in terms of type of myeloma, stage at diagnosis, time from diagnosis to transplantation, CD34 cell dose, engraftment kinetics, and 100-day response rates. Serum creatinine was higher and patients were relatively older in both the planned inpatient (median age, 62 years; range, 33 to 80 years) and unplanned (median age, 59 years; range, 44 to 69 years) admission cohorts compared with the outpatient-only cohort (median age, 57 years; range, 40 to 70 years) (P Performance status (cohort A: median, 90%; range, 60% to 100%; cohort B: 80%, 50% to 100%; cohort C: 80%, 60% to 100%) was lower (P performance status (KPS 2 also appeared to be associated with worse outcomes compared with HCT-CI 0 to 1, the the difference did not reach statistical significance (hazard ratio, 1.41l 95% confidence interval, 0.72 to 2.76). Only 1 patient out of 448 died from a transplantation

  4. Advanced fuel technology and performance: Current status and trends

    International Nuclear Information System (INIS)

    1990-11-01

    During the last years the Nuclear Fuel Cycle and Waste Management Division of the IAEA has been giving great attention to the collection, analysis and exchange of information in the field of reactor fuel technology. Most of these activities are being conducted in the framework of the International Working Group on Water Reactor Fuel Performance and Technology (IWGFPT). The purpose of this Advisory Group Meeting on Advanced Fuel Technology and Performance was to update and to continue the previous work, and to review the experience of advanced fuel technology, its performance with regard to all types of reactors and to outline the future trends on the basis of national experience and discussions during the meeting. As a result of the meeting a Summary Report was prepared which reflected the status of the advanced nuclear fuel technology up to 1990. The 10 papers presented by participants of this meeting are also published here. A separate abstract was prepared for each of these papers. Refs, figs and tabs

  5. The National Ignition Facility 2007 laser performance status

    Energy Technology Data Exchange (ETDEWEB)

    Haynam, C A; Sacks, R A; Wegner, P J; Bowers, M W; Dixit, S N; Erbert, G V; Heestand, G M; Henesian, M A; Hermann, M R; Jancaitis, K S; Manes, K R; Marshall, C D; Mehta, N C; Menapace, J; Nostrand, M C; Orth, C D; Shaw, M J; Sutton, S B; Williams, W H; Widmayer, C C [Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore, CA, 94550 (United States)], E-mail: haynam1@llnl.gov (and others)

    2008-05-15

    The National Ignition Facility (NIF) at Lawrence Livermore National Laboratory contains a 192-beam 3.6 MJ neodymium glass laser that is frequency converted to 351nm light. It has been designed to support high energy density science (HEDS), including the demonstration of fusion ignition through Inertial Confinement. To meet this goal, laser design criteria include the ability to generate pulses of up to 1.8-MJ total energy at 351nm, with peak power of 500 TW and precisely-controlled temporal pulse shapes spanning two orders of magnitude. The focal spot fluence distribution of these pulses is conditioned, through a combination of special optics in the 1{omega} (1053 nm) portion of the laser (continuous phase plates), smoothing by spectral dispersion (SSD), and the overlapping of multiple beams with orthogonal polarization (polarization smoothing). In 2006 and 2007, a series of measurements were performed on the NIF laser, at both 1{omega} and 3{omega} (351 nm). When scaled to full 192-beam operation, these results lend confidence to the claim that NIF will meet its laser performance design criteria and that it will be able to simultaneously deliver the temporal pulse shaping, focal spot conditioning, peak power, shot-to-shot reproducibility, and power balance requirements of indirect-drive fusion ignition campaigns. We discuss the plans and status of NIF's commissioning, and the nature and results of these measurement campaigns.

  6. The SSG Wave Energy Converter: Performance, Status and Recent Developments

    Directory of Open Access Journals (Sweden)

    Mariano Buccino

    2012-01-01

    Full Text Available The Sea-wave Slot-cone Generator (SSG is a Wave Energy Converter based on the wave overtopping principle; it employs several reservoirs placed on top of each other, in which the energy of incoming waves is stored as potential energy. Then, the captured water runs through turbines for electricity production. The system works under a wide spectrum of different wave conditions, giving a high overall efficiency. It can be suitable for shoreline and breakwater applications and presents particular advantages, such as sharing structure costs, availability of grid connection and recirculation of water inside the harbor, as the outlet of the turbines is on the rear part of the system. Recently, plans for the SSG pilot installations are in progress at the Svaaheia site (Norway, the port of Hanstholm (Denmark and the port of Garibaldi (Oregon, USA. In the last-mentioned two projects, the Sea-wave Slot-cone Generator technology is integrated into the outer harbor breakwater and jetty reconstruction projects. In the last years extensive studies have been performed on the hydraulic and the structural response of this converter, with the aim of optimizing the design process. The investigations have been conducted by physical model tests and numerical simulations and many results have been published on both conference proceedings and journals. The main scope of this paper is reviewing the most significant findings, to provide the reader with an organic overview on the present status of knowledge.

  7. Sentinel-5 instrument: status of design, performance, and development

    Science.gov (United States)

    Gühne, T.; Keim, C.; Bartsch, P.; Weiß, S.; Melf, M.; Seefelder, W.

    2017-09-01

    The Sentinel-5 instrument is currently under development by a consortium led by Airbus Defence and Space in the frame of the European Union Copernicus program. It is a customer furnished item to the MetOp Second Generation satellite platform, which will provide operational meteorological data for the coming decades. Mission objective of the Sentinel-5 is to monitor the composition of the Earth atmosphere for Copernicus Atmosphere Services by taking measurements of trace gases and aerosols impacting air quality and climate with high resolution and daily global coverage. Therefore the Sentinel-5 provides five dispersive spectrometers covering the UV-VIS (270…500 nm), NIR (685 …773 nm) and SWIR (1590…1675 and 2305…2385 nm) spectral bands with resolutions <=1nm. Spatially the Sentinel-5 provides a 108° field of view with a ground sampling of 7.5 x 7 km2 at Nadir. The development program is post PDR and the build-up of the industrial team is finalised. We report on the instrument architecture and design derived from the driving requirements, the predicted instrument performance, and the general status of the program.

  8. Reproductive performance and nutritional status of Holstein cows in Brazil

    International Nuclear Information System (INIS)

    Meirelles, C.F.; Vitti, D.M.S.S.; Abdalla, A.L.

    1990-01-01

    Reproductive performance and nutritional status were assessed in Holstein cows from two dairy herds in Sao Paulo State, Brazil. In the first herd (good management, G), concentrate was fed individually to cows, complete records were kept, veterinary services were provided as necessary and the standard of husbandry practices was good. In the second herd (fair management, F), veterinary services were used only occasionally, the concentrate fed was divided equally among lactating cows and the standard of husbandry practices was only fair. Haemoglobin, haematocrit, glucose, total protein and phosphorus were measured in blood collected at various times after calving. There were no statistical differences between the blood parameters in the two herds except for inorganic phosphorus which differed significantly between farms (P < 0.01). Only plasma glucose had a significant (P < 0.01) effect on the time required by the animals to initiate post-partum ovarian activity. The proportion of cows ovulating by day 60 was 75% in herd G versus 53% in herd F (P < 0.01); by day 100 the values were 82% in herd G and 70% in herd F (P < 0.01). Calving intervals were 12.7 and 13.2 months for herds G and F respectively, suggesting comparable reproductive efficiency. However, only 1 of the 28 cows in herd G was open more than 365 days after calving, as opposed to 5 of the 30 cows in herd F. When a value of 365 open days was given for these non-pregnant cows, the average days open for the herds were then 123 and 154 days for herds G and F respectively, indicating a decided production advantage in favour of the better managed herd. (author). 16 refs, 1 fig., 2 tabs

  9. Fail or flourish? Cognitive appraisal moderates the effect of solo status on performance.

    Science.gov (United States)

    White, Judith B

    2008-09-01

    When everyone in a group shares a common social identity except one individual, the one who is different from the majority has solo status. Solo status increases one's visibility and performance pressure, which may result in stress. Stress has divergent effects on performance, and individuals' response to stressful situations is predicted by their cognitive appraisal (challenge or threat) of the situation. Two experiments test the hypothesis that cognitive appraisal moderates the effect of solo status on performance. Experiment 1 finds that at relatively high appraisal levels (resources exceed demands), solo status improves men's and women's performance; at relatively low appraisal levels, solo status hurts performance. Experiment 2 replicates this effect for solo status based on minimal group assignment. Results suggest that for individuals who feel challenged and not threatened by their work, it may help to be a solo.

  10. DAΦNE Control System status and performance

    International Nuclear Information System (INIS)

    Di Pirro, G.; Drago, A.; Mazzitelli, G.; Milardi, C.; Sannibale, F.; Stecchi, A.; Stella, A.

    1998-01-01

    The DAΦNE Control System allowed the step by step commissioning of the major subsystems as they were installed, proving to be modular and extensible. Recently the guidelines of the Control System evolution concerned the development of machine operational procedures and the integration of diagnostic tools. Particular attention has been reserved to the problem of saving and restoring element data sts as well as to the DAΦNE general data handling. A system overview including installation status, features, and operation results is presented

  11. Hierarchy stability moderates the effect of status on stress and performance in humans.

    Science.gov (United States)

    Knight, Erik L; Mehta, Pranjal H

    2017-01-03

    High social status reduces stress responses in numerous species, but the stress-buffering effect of status may dissipate or even reverse during times of hierarchical instability. In an experimental test of this hypothesis, 118 participants (57.3% female) were randomly assigned to a high- or low-status position in a stable or unstable hierarchy and were then exposed to a social-evaluative stressor (a mock job interview). High status in a stable hierarchy buffered stress responses and improved interview performance, but high status in an unstable hierarchy boosted stress responses and did not lead to better performance. This general pattern of effects was observed across endocrine (cortisol and testosterone), psychological (feeling in control), and behavioral (competence, dominance, and warmth) responses to the stressor. The joint influence of status and hierarchy stability on interview performance was explained by feelings of control and testosterone reactivity. Greater feelings of control predicted enhanced interview performance, whereas increased testosterone reactivity predicted worse performance. These results provide direct causal evidence that high status confers adaptive benefits for stress reduction and performance only when the social hierarchy is stable. When the hierarchy is unstable, high status actually exacerbates stress responses.

  12. Iron nutrition and premenopausal women: effects of poor iron status on physical and neuropsychological performance.

    Science.gov (United States)

    McClung, James P; Murray-Kolb, Laura E

    2013-01-01

    Iron is a nutritionally essential trace element that functions through incorporation into proteins and enzymes, many of which contribute to physical and neuropsychological performance. Poor iron status, including iron deficiency (ID; diminished iron stores) and iron deficiency anemia (IDA; poor iron stores and diminished hemoglobin), affects billions of people worldwide. This review focuses on physical and neuropsychological outcomes associated with ID and IDA in premenopausal women, as the prevalence of ID and IDA is often greater in premenopausal women than other population demographics. Recent studies addressing the physiological effects of poor iron status on physical performance, including work productivity, voluntary activity, and athletic performance, are addressed. Similarly, the effects of iron status on neurological performance, including cognition, affect, and behavior, are summarized. Nutritional countermeasures for the prevention of poor iron status and the restoration of decrements in performance outcomes are described.

  13. Estimates of Job Performance for Applicants Differing in Gender, Marital and Parental Status.

    Science.gov (United States)

    Borges, Marilyn A.; Clothier, Tamara A.

    Women and men tend to be defined by their marital and parental status; thus, these factors may be crucial in understanding societal attitudes toward working men and women. The influence of marital and parental status on perceived job performance was investigated with a college undergraduate sample (N=128). From paragraph descriptions that varied…

  14. MSFC Turbine Performance Optimization (TPO) Technology Verification Status

    Science.gov (United States)

    Griffin, Lisa W.; Dorney, Daniel J.; Snellgrove, Lauren M.; Zoladz, Thomas F.; Stroud, Richard T.; Turner, James E. (Technical Monitor)

    2002-01-01

    Capability to optimize for turbine performance and accurately predict unsteady loads will allow for increased reliability, Isp, and thrust-to-weight. The development of a fast, accurate, validated aerodynamic design, analysis, and optimization system is required.

  15. Cassini Radar EQM Model: Instrument Description and Performance Status

    Science.gov (United States)

    Borgarelli, L.; Faustini, E. Zampolini; Im, E.; Johnson, W. T. K.

    1996-01-01

    The spaeccraft of the Cassini Mission is planned to be launched towards Saturn in October 1997. The mission is designed to study the physical structure and chemical composition of Titan. The results of the tests performed on the Cassini radar engineering qualification model (EQM) are summarized. The approach followed in the verification and evaluation of the performance of the radio frequency subsystem EQM is presented. The results show that the instrument satisfies the relevant mission requirements.

  16. NASA Soil Moisture Active Passive Mission Status and Science Performance

    Science.gov (United States)

    Yueh, Simon H.; Entekhabi, Dara; O'Neill, Peggy; Njoku, Eni; Entin, Jared K.

    2016-01-01

    The Soil Moisture Active Passive (SMAP) observatory was launched January 31, 2015, and its L-band radiometer and radar instruments became operational since mid-April 2015. The SMAP radiometer has been operating flawlessly, but the radar transmitter ceased operation on July 7. This paper provides a status summary of the calibration and validation of the SMAP instruments and the quality assessment of its soil moisture and freeze/thaw products. Since the loss of the radar in July, the SMAP project has been conducting two parallel activities to enhance the resolution of soil moisture products. One of them explores the Backus Gilbert optimum interpolation and de-convolution techniques based on the oversampling characteristics of the SMAP radiometer. The other investigates the disaggregation of the SMAP radiometer data using the European Space Agency's Sentinel-1 C-band synthetic radar data to obtain soil moisture products at about 1 to 3 kilometers resolution. In addition, SMAP's L-band data have found many new applications, including vegetation opacity, ocean surface salinity and hurricane ocean surface wind mapping. Highlights of these new applications will be provided.

  17. Multidimensional Monitoring of Recovery Status and Implications for Performance.

    Science.gov (United States)

    Heidari, Jahan; Beckmann, Jürgen; Bertollo, Maurizio; Brink, Michel; Kallus, Wolfgang; Robazza, Claudio; Kellmann, Michael

    2018-03-15

    Monitoring of recovery in the context of athletic performance has gained significant importance during recent years. As a systematic process of data collection and evaluation, the monitoring of recovery can be implemented for various purposes. It may aid to prevent negative outcomes of training or competition, such as underrecovery, overtraining, or injuries. Further, it aims at establishing routines and strategies necessary to guarantee athletes' readiness for performance by restoring their depleted resources. Comprehensive monitoring of recovery ideally encompasses a multidimensional approach, thereby considering biological, psychological, and social monitoring methods. From a biological perspective, physiological (e.g., cardiac parameters), biochemical (e.g., creatine kinase), hormonal (e.g., salivary cortisol) and immunological (e.g., immunoglobulin A) markers can be taken into account to operationalize training loads and recovery needs. Psychological approaches suggest the application of validated and reliable psychometric questionnaires (e.g., Recovery-Stress Questionnaire for Athletes) to measure a subjective perception of recovery as well as the subjective degree of training- or competition-induced fatigue. Social aspects also play a role in performance monitoring and may hence provide essential performance-related information. The implementation of a monitoring routine within athletic environments represents a continuous process which functions as an effective addition to training and depends on a range of conditions (e.g., organizational regulations, commitment of athletes). Current research in the field of monitoring aims at establishing individualized monitoring regimes that are referring to intraindividual reference values with the help of innovative technological devices.

  18. Growth performance and immunity status of starter broiler birds ...

    African Journals Online (AJOL)

    This study was conducted to investigate the effects of feeding diets containing Neem Leaf Meal (NLM), Garlic Meal (GM) and their combinations (NLM + GM) on growth performance and serum parameters of starter broiler birds. A total of 180 day-old Cobb broiler chickens were divided into twelve groups of fifteen chicks with ...

  19. Effects of ownership and financial status on corporate environmental performance

    Czech Academy of Sciences Publication Activity Database

    Earnhart, D.; Lízal, Lubomír

    2002-01-01

    Roč. 13, č. 4-5 (2002), s. 67-68 ISSN 1020-5470 Institutional research plan: CEZ:AV0Z7085904 Keywords : ownership structures * privatization * financial performance Subject RIV: AH - Economics http://go.worldbank.org/JL12RVXEW0

  20. Status of development and irradiation performance of advanced proliferation resistant MTR fuel at NUKEM

    International Nuclear Information System (INIS)

    Hrovat, M.; Hassel, H.-W.; Wehner, E.

    1985-01-01

    This paper describes the current status of development and irradiation performance of fuel elements for Material Test and Research (MTR) Reactors with Medium Enriched Uranium (MEU, ≤ 45 % 235-U) and Low Enriched Uranium (LEU, ≤ 20 % 235-U). (author)

  1. Socioeconomic Status and Performance in the US Army and US Marine Corps

    National Research Council Canada - National Science Library

    Booth, Stefan

    1998-01-01

    The purpose or this study was to examine socioeconomic status (SES) of recruits in the Army and Marine Corps and to analyze the relationship between a recruit's SES background and his or her performance in the military over time...

  2. Performance analysis of spectrum sensing with multiple status changes in primary user traffic

    KAUST Repository

    Tang, Liang; Chen, Yunfei; Hines, Evor L.; Alouini, Mohamed-Slim

    2012-01-01

    In this letter, the impact of primary user traffic with multiple status changes on the spectrum sensing performance is analyzed. Closed-form expressions for the probabilities of false alarm and detection are derived. Numerical results show

  3. Methodology of the Integrated Analysis of Company's Financial Status and Its Performance Results

    OpenAIRE

    Mackevičius, Jonas; Valkauskas, Romualdas

    2010-01-01

    Information about company's financial status and its performance results is very important for the objective evaluation of company's position in the market and competitive possibilities in the future. Such information is provided in the financial statement. It is important to apply and investigate this information properly. The methodology of company's financial status and performance results integrated analysis is recommended in this article. This methodology consists of these three elements...

  4. The SSG Wave Energy Converter: Performance, Status and Recent Developments

    DEFF Research Database (Denmark)

    Vicinanza, Diego; Margheritini, Lucia; Kofoed, Jens Peter

    2012-01-01

    through turbines for electricity production. The system utilizes a wide spectrum of different wave conditions by means of multiple reservoirs, located at different levels above the still water level. Thereby, it obtains a high overall efficiency and it can be suitable for shoreline and breakwater...... applications, presenting particular advantages such as: sharing structure costs, availability of grid connection and infrastructures, recirculation of water inside the harbor, as the outlet of the turbines is on the rear part of the system. Recently, plans for the SSG pilot installation were in progress...... on wave loadings and on hydraulic performances (overtopping and reflection) in order to optimize the structure design. This paper addresses the influence of various parameters (geometry, wave characteristics) on overtopping, reflection and wave loading and it draws conclusions on performances...

  5. The relationship between school absence, academic performance, and asthma status.

    Science.gov (United States)

    Moonie, Sheniz; Sterling, David A; Figgs, Larry W; Castro, Mario

    2008-03-01

    Children with asthma experience more absenteeism from school compared with their nonasthma peers. Excessive absenteeism is related to lower student grades, psychological, social, and educational adjustment. Less is known about the relationship between the presence of asthma and the academic achievement in school-aged children. Since students with asthma miss more days from school, this may negatively impact their academic achievement. The goal of this study was to investigate the relationships between absenteeism, presence of asthma, and asthma severity level with standardized test level performance in a predominantly African American urban school district. A cross-sectional analysis was conducted of 3812 students (aged 8-17 years) who took the Missouri Assessment Program (MAP) standardized test during the 2002-2003 academic year. After adjustment for covariates, a significant inverse relationship was found between absenteeism and test level performance on the MAP standardized test in all children (F = 203.9, p achievement between those with and without asthma (p = .12). Though not statistically different, those with persistent asthma showed a modestly increased likelihood of scoring below Nearing Proficient compared with those with mild intermittent asthma (adjusted odds ratio = 1.93, 95% confidence intervals = 0.93-4.01, p = .08). A negative impact of absenteeism on standardized test level achievement was demonstrated in children from an urban African American school district. Children with asthma perform the same academically as their nonasthma peers. However, those with persistent asthma show a trend of performing worse on MAP standardized test scores and have more absence days compared with other students. More research is warranted on the effects of persistent asthma on academic achievement.

  6. Present Status and Extensions of the Monte Carlo Performance Benchmark

    Science.gov (United States)

    Hoogenboom, J. Eduard; Petrovic, Bojan; Martin, William R.

    2014-06-01

    The NEA Monte Carlo Performance benchmark started in 2011 aiming to monitor over the years the abilities to perform a full-size Monte Carlo reactor core calculation with a detailed power production for each fuel pin with axial distribution. This paper gives an overview of the contributed results thus far. It shows that reaching a statistical accuracy of 1 % for most of the small fuel zones requires about 100 billion neutron histories. The efficiency of parallel execution of Monte Carlo codes on a large number of processor cores shows clear limitations for computer clusters with common type computer nodes. However, using true supercomputers the speedup of parallel calculations is increasing up to large numbers of processor cores. More experience is needed from calculations on true supercomputers using large numbers of processors in order to predict if the requested calculations can be done in a short time. As the specifications of the reactor geometry for this benchmark test are well suited for further investigations of full-core Monte Carlo calculations and a need is felt for testing other issues than its computational performance, proposals are presented for extending the benchmark to a suite of benchmark problems for evaluating fission source convergence for a system with a high dominance ratio, for coupling with thermal-hydraulics calculations to evaluate the use of different temperatures and coolant densities and to study the correctness and effectiveness of burnup calculations. Moreover, other contemporary proposals for a full-core calculation with realistic geometry and material composition will be discussed.

  7. Present status and extensions of the Monte Carlo performance benchmark

    International Nuclear Information System (INIS)

    Hoogenboom, J.E.; Petrovic, B.; Martin, W.R.

    2013-01-01

    The NEA Monte Carlo Performance benchmark started in 2011 aiming to monitor over the years the abilities to perform a full-size Monte Carlo reactor core calculation with a detailed power production for each fuel pin with axial distribution. This paper gives an overview of the contributed results thus far. It shows that reaching a statistical accuracy of 1 % for most of the small fuel zones requires about 100 billion neutron histories. The efficiency of parallel execution of Monte Carlo codes on a large number of processor cores shows clear limitations for computer clusters with common type computer nodes. However, using true supercomputers the speedup of parallel calculations is increasing up to large numbers of processor cores. More experience is needed from calculations on true supercomputers using large numbers of processors in order to predict if the requested calculations can be done in a short time. As the specifications of the reactor geometry for this benchmark test are well suited for further investigations of full-core Monte Carlo calculations and a need is felt for testing other issues than its computational performance, proposals are presented for extending the benchmark to a suite of benchmark problems for evaluating fission source convergence for a system with a high dominance ratio, for coupling with thermal-hydraulics calculations to evaluate the use of different temperatures and coolant densities and to study the correctness and effectiveness of burnup calculations. Moreover, other contemporary proposals for a full-core calculation with realistic geometry and material composition will be discussed. (authors)

  8. The WIYN One Degree Imager - Status and Performance

    Science.gov (United States)

    Boroson, Todd A.

    2013-06-01

    A preliminary version of the WIYN One Degree Imager (ODI) has been commissioned and put into scientific operation. ODI was designed to take advantage of the excellent image quality and wide field of view of the WIYN 3.5m telescope. It will do this by covering a one square degree focal plane with orthogonal transfer array (OTA) detectors, which have the capability to correct for image motion during the exposure in regions approximately the size of the isokinetic patch. The partial ODI (pODI) differs from the complete ODI in two ways - only 13 of the 64 OTAs populate the focal plane, and only coherent image motion correction is enabled. However, this implementation has allowed the commissioning of the instrument with all subsystems except the additional detectors in place. The 13 OTAs are configured as a 24 X 24 arcminute “science field”, plus 4 outer OTAs, allowing the sampling of all radii within the one square degree field. pODI is now in use for science observations as we prepare to upgrade the focal plane. The performance of pODI is excellent. Image quality is site seeing limited, and, on good seeing nights, we can achieve images around 0.4 arcsec FWHM over the entire field. The guide signal, from selected regions in the outer OTAs, can be passed to the telescope exclusively, or the high frequency component can be applied as a global shift to the OTAs. We are still in the process of characterizing the gains from this coherent correction, but the detectors perform well in this mode. Data are immediately transferred to an archive at Indiana University, where they are pipeline-processed to remove instrumental signature. The OTA detectors perform adequately in terms of read noise, full well, sensitivity, and dark current. They show 2 anomalies: (1) regions in the circuitry outside the imaging area glow under certain circumstances, and (2) a low level degradation of charge transfer efficiency is present between the imaging area and the serial registers. We have

  9. Improved iodine status is associated with improved mental performance of schoolchildren in Benin.

    Science.gov (United States)

    van den Briel, T; West, C E; Bleichrodt, N; van de Vijver, F J; Ategbo, E A; Hautvast, J G

    2000-11-01

    An adequate iodine supply in utero and shortly after birth is known to be crucial to an individual's physical and mental development. The question of whether iodine supplementation later in life can exert a favorable influence on the mental performance of iodine-deficient populations was addressed in various studies, but with contradictory results. The aim of this study was to examine the effect of an improvement in iodine status on mental and psychomotor performance of schoolchildren (7-11 y) who were moderately to severely iodine deficient. The study, which was originally planned as a double-blind, randomized, placebo-controlled intervention, was carried out in an iodine-deficient population of schoolchildren (n = 196) in northern Benin. As the population began to have access to iodized salt during the 1-y intervention period, the study population was split post hoc-on the basis of urinary iodine concentrations-into a group with improved iodine status and a group with unchanged iodine status. Changes in mental and psychomotor performance over the intervention period were compared. Children with increased urinary iodine concentrations had a significantly greater increase in performance on the combination of mental tests than did the group with no change in urinary iodine concentrations. An improvement in iodine status, rather than iodine status itself, determined mental performance in this population, which was initially iodine deficient. These findings suggest a "catch-up" effect in terms of mental performance.

  10. The association of iron status with educational performance and intelligence among adolescents.

    Science.gov (United States)

    Dissanayake, D S; Kumarasiri, P V R; Nugegoda, D B; Dissanayake, D M

    2009-09-01

    The aim was to identify the association of iron status with educational performance and intelligence of adolescents. This was a cross sectional comparative study among adolescents aged 13-15 years. Each iron deficient student was matched with an iron sufficient student from the same school, class and sex. Iron status was based on haemoglobin and serum ferritin levels. The marks for mathematics, science, Sinhala language and social science were considered to assess educational performance. Intelligence was measured by Raven's Standard progressive matrices. All the possible confounders and effect modifiers were considered. Home visits to a sub-sample checked the quality of data. The final analysis included 188 students (94 matched pairs). Neither educational performance nor intelligence showed significant associations with the iron status. The severity of the iron deficiency did not relate to these cognitive variables either. Twenty-three and 8 co-variables showed statistically significant associations with educational performance and intelligence respectively. Following a multiple regression analysis intelligence, the enthusiasm of the student towards learning, occupational ambition, household possession, problems at home and private tuition for mathematics were key factors predicting educational performance. Stunting and educational level of the mother were important factors influencing intelligence. Iron status does not play a major role in educational performance and intelligence of school going adolescents. Several factors affect educational performance and intelligence. This study highlights the difficulty in extrapolating the findings of similar studies to different ecological settings.

  11. [ASSOCIATION BETWEEN FITNESS, NUTRITIONAL STATUS AND ACADEMIC PERFORMANCE IN PHYSICAL EDUCATION STUDENTS].

    Science.gov (United States)

    Godoy Cumillaf, Andrés; Valdés Badilla, Pablo; Fariña Herrera, Custodio; Cárcamo Mora, Francisco; Medina Herrera, Bernice; Meneses Sandoval, Elías; Gedda Muñoz, Relmu; Durán Agüero, Samuel

    2015-10-01

    several studies demonstrated that regular physical exercise would impact positively on the academic performance of students. to determine the association between physical fitness, nutritional status and academic performance of students of Pedagogy in Physical Education from Temuco, Chile. the sample was selected on a non-probabilistic approach, which included 208 subjects (n = 153 women and n = 55 women). The variables studied were physical fitness (short Abs, long jump with feet together, forward trunk flexion, elbow flexion and extension and "course navette" test), nutritional status (BMI) and academic performance (classified as up and down the academic average). 87.5% of students have a satisfactory fitness and a BMI of 23.8 ± 2.9 kg/m2. The students with the best academic performance were those with the higher proportion of satisfactory physical condition (92.5 %). No association between academic performance and nutritional status was determined, but it was observed between low fitness and a great risk of low academic performance (OR = 2.8, 95% CI 1.0 to 8 1; p academic achievement and physical fitness among students is observed, but no for the nutritional status and the academic performance. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  12. Taking the reins: the effects of new leader status and leadership style on team performance.

    Science.gov (United States)

    Sauer, Stephen J

    2011-05-01

    New leaders face a challenging task when they take charge of their teams. They have to determine how best to guide the work process, and they must understand how their behaviors will affect the members of their team. This research examines how a newly assigned team leader's status moderates subordinates' reactions to different leadership styles to affect assessments of the leader's self-confidence and effectiveness, and how this impacts team performance. Across 2 experimental studies, results demonstrate that low-status leaders are rated as more effective when they use a directive style, whereas high-status leaders are viewed as more effective when they use a participative style, and this relationship is mediated by perceptions of self-confidence. In addition, teams whose leaders are viewed more favorably perform better on a complex group task. These findings imply that low-status individuals are able to enhance their level of personal power by drawing on whatever positional power they hold, whereas high-status individuals are better off relying solely on their personal power to influence others. This research also provides a clear demonstration that assessments of new leaders' behaviors are subject to an appraisal that is clouded by observers' status perceptions and attributions.

  13. STATUS BERKELANJUTAN KOTA TANGERANG SELATAN-BANTEN DENGAN MENGGUNAKAN KEY PERFORMANCE INDICATORS (Sustainable Status of South Tangerang City-Banten Using Key Performance Indicators

    Directory of Open Access Journals (Sweden)

    Heri Apriyanto

    2015-07-01

    Full Text Available ABSTRAK Pembangunan kota yang tidak terkendali akan mengakibatkan tekanan terhadap lingkungan dan beban masyarakat meningkat, sebaliknya degradasi lingkungan akan mengakibatkan pembatasan pengembangan ekonomi dan penurunan kualitas hidup. Guna mencegah terjadinya dampak-dampak negatif, maka diperlukan prinsip-prinsip pembangunan kota yang berkelanjutan. Evaluasi terhadap pelaksanan pembangunan kota yang berkelanjutan perlu dilakukan untuk mengetahui apakah pembangunan suatu kota sudah atau belum/tidak berkelanjutan. Penelitian ini bertujuan untuk menyusun Key Performance Indicators (KPI guna menilai status pembangunan kota berkelanjutan. Perumusan KPI ini dilakukan dengan pendekatan Analytic Hierarchy Process (AHP. KPI yang dihasilkan terdiri dari 21 indikator dan 9 elemen dari 3 pilar pembangunan berkelanjutan (ekonomi, sosial, dan lingkungan. Implementasi KPI dilakukan untuk pengukuran status keberlanjutan Kota Tangerang Selatan. Hasil pengukuran menunjukkan bahwa kota ini termasuk dalam tahap awal pembangunan berkelanjutan. Secara umum perkembangan ekonomi dan sosial relatif cukup baik, namun tidak demikian dengan kondisi lingkungannya. ABSTRACT Uncontrolled urban development will result in pressure on the environment and the burden of the people. On the contrary, environmental degradation will lead to restricted economic development and decreased quality of life. In order to prevent negative impacts, it is necessary to implement the principles of sustainable city development. Evaluation of the implementation of sustainable city development is needed to determine whether the development of a city is sustainable or not. This study aimed to develop Key Performance Indicators (KPI to assess the status of sustainable city development. The formulation of KPI is done with Analytic Hierarchy Process (AHP. KPI generated consists of 21 indicators and 9 elements of the 3 pillars of sustainable development (economic, social, and environmental

  14. Cardiorespiratory fitness and academic performance association is mediated by weight status in adolescents: DADOS study.

    Science.gov (United States)

    Beltran-Valls, María Reyes; Adelantado-Renau, Mireia; Castro-Piñero, Jose; Sánchez-López, Mairena; Moliner-Urdiales, Diego

    2018-04-28

    The aim of our study was to examine the mediation effect of weight status on the association between cardiorespiratory fitness (CRF) and academic performance (AP). Two hundred sixty-nine adolescents (140 boys) aged 13.9 ± 0.3 years old from the DADOS study were included in this cross-sectional analysis. CRF was assessed by the 20-m shuttle run test and estimated maximum oxygen uptake was used in the analysis. AP was assessed through the final academic grades and the Science Research Associates Test of Educational Abilities for assessing reasoning, verbal, and numeric abilities. Weight status was assessed by body mass index (kg/m 2 ). Boot-strapped mediation procedures were performed and indirect effects (IE) with confidence intervals (CI) not including zero were considered statistically significant. Mediation analysis revealed that weight status acted as a mediator of the relationship of CRF with reasoning ability (IE = 0.039; CI = 0.001; 0.091) and the final grades in Math (IE = 0.011; CI = 0.002; 0.025), Language (IE = 0.013; CI = 0.004; 0.027), and GPA (IE = 0.011; CI = 0.003; 0.023). Our data show that the influence of CRF on academic performance is mediated by weight status in adolescents. We suggest that our data could be considered by educators, families, and policy makers, so that active lifestyles might be promoted when designing programs aimed to improve AP among adolescents. What is Known: • Academic performance is associated with both, cardiorespiratory fitness and weight status. • The role of weight status in the association between cardiorespiratory fitness and academic performance is poorly understood. What is New: • We support the scarce research investigating the mediating role of weight status as mechanism in the association between fitness and academic performance in youth. • Previous knowledge is expanded by suggesting that cardiorespiratory fitness is related to weight status which in turn may

  15. The Variable and Changing Status of Performance Art Relics and Artifacts in Museum Collections

    DEFF Research Database (Denmark)

    Cone, Louise

    2017-01-01

    The status of an artwork in a museum collection is variable and contingent upon factors and parameters that are specific not only to the logic of the museum world but also to factors extrinsic to the museum. In particular older performance art 'relics' are subject to contextual interpretations...

  16. From Social Class to Self-Efficacy: Internalization of Low Social Status Pupils' School Performance

    Science.gov (United States)

    Wiederkehr, Virginie; Darnon, Céline; Chazal, Sébastien; Guimond, Serge; Martinot, Delphine

    2015-01-01

    Previous research has largely documented that socioeconomic status (SES) is a strong and consistent predictor of pupils' school performance in several countries. In this research, we argue that children internalize the SES achievement gap in the form of a lower/higher sense of school self-efficacy. In two studies, teenaged students' (Study 1) and…

  17. Contextual Influences on Children's Mental Health and School Performance: The Moderating Effects of Family Immigrant Status

    Science.gov (United States)

    Georgiades, Katholiki; Boyle, Michael H.; Duku, Eric

    2007-01-01

    Data from a nationally representative sample of 13,470 children aged 4-11 years were used to study contextual influences on children's mental health and school performance, the moderating effects of family immigrant status and underlying family processes that might explain these relationships. Despite greater socioeconomic disadvantage, children…

  18. Student Performance and Family Socioeconomic Status: Results from a Survey of Compulsory Education in Western China

    Science.gov (United States)

    Liu, Xiaofei; Lu, Ke

    2008-01-01

    This study used fifteen-year-old ninth-grade students from rural areas of five provinces in western China as samples to carry out research on the relationship between the socioeconomic status of Chinese families and student academic performance. Based on parents' educational background, occupation, family economic conditions, and other factors,…

  19. Does Socioeconomic Status Explain the Relationship between Admissions Tests and Post-Secondary Academic Performance?

    Science.gov (United States)

    Sackett, Paul R.; Kuncel, Nathan R.; Arneson, Justin J.; Cooper, Sara R.; Waters, Shonna D.

    2009-01-01

    Critics of educational admissions tests assert that tests measure nothing more than socioeconomic status (SES) and that their apparent validity in predicting academic performance is an artifact of SES. The authors examined multiple large data sets containing data on admissions and related tests, SES, and grades showing that (a) SES is related to…

  20. Academic performance of Korean children is associated with dietary behaviours and physical status.

    Science.gov (United States)

    Kim, Hye-Young P; Frongillo, Edward A; Han, Sung-Sook; Oh, Se-Young; Kim, Woo-Kyung; Jang, Young-Ai; Won, Hye-Sook; Lee, Hyun-Sook; Kim, Sook-He

    2003-01-01

    The purpose of this study was to obtain a fuller understanding of the association of dietary behaviours, physical status and socio-economic status with academic performance in Korean teenagers. The subjects in this study were 6,463 boys and girls, in grade 5, 8, and 11 in Korea. A self-administered questionnaire and the food-frequency form were used. Grade point average (GPA), height, weight, and physical fitness score for the year were recorded from the school record. The academic performance of students was strongly associated with dietary behaviours, especially with regularity of three meals even after control for parent's education level. Regular breakfast and lunch were more important in grades 5 and 8, while regular dinner was more related with academic performance in grade 11. Small, positive associations of height and physical fitness to academic performance were also found. The relative importance of regularity of meals was greater than that of socio-economic status and physical status in older teenagers. The results of this study suggest that accommodation of better dietary environment and nutrition education for three regular meals is recommended.

  1. Does performance status influence the outcome of Nd:YAG laser therapy of proximal esophageal tumors?

    NARCIS (Netherlands)

    Alexander, G. L.; Wang, K. K.; Ahlquist, D. A.; Viggiano, T. R.; Gostout, C. J.; Balm, R.

    1994-01-01

    The value of endoscopic palliative therapy for malignant obstruction in the proximal esophagus has been questioned. To assess the importance of pre-treatment performance status on treatment outcome, we reviewed the records of patients with tumors of the proximal esophagus undergoing endoscopic laser

  2. Influence of thermally peroxidized soybean oil on growth performance and oxidative status in growing pigs

    Science.gov (United States)

    The objective of this study was to evaluate the effect of feeding peroxidized soybean oil (SO) on growth performance and oxidative status in growing pigs. Fifty-six barrows (25.3 ± 3.3 kg initial BW) were randomly assigned to one of four diets containing either 10% fresh SO (22.5 C) or SO exposed to...

  3. A longitudinal study of childhood obesity, weight status change, and subsequent academic performance in Taiwanese children.

    Science.gov (United States)

    Chen, Li-Jung; Fox, Kenneth R; Ku, Po-Wen; Wang, Ching-Hui

    2012-09-01

    This study examined the association among childhood obesity, weight status change, and subsequent academic performance at 6-year follow-up. First-grade students from one elementary school district in Taichung City, Taiwan were followed for 6 years (N = 409). Academic performance was extracted from the school records at the end of each grade. Weight and height were measured at the beginning of each grade. A weight change variable was created based on each child's weight status difference at grades 1 and 6. A multivariate linear regression model for predicting academic performance at grade 6 was developed with adjustment for individual characteristics and family factors. A latent growth curve (LGC) showed the association between changes in body mass index (BMI) and in academic performance across a 6-year period. BMI in children increased significantly across 6 years. The rate of increase in BMI over 6 years was higher for children with higher baseline BMIs than it was for children with lower baseline BMIs. However, BMI changes were not significantly associated with changes of academic performance. There was no significant relationship between initial obesity or change in weight status and subsequent academic performance. It appears that either being or becoming overweight/obese did not impact academic achievement for these Taiwanese children. © 2012, American School Health Association.

  4. The effects of individual status and group performance on network ties among teammates in the National Basketball Association.

    Directory of Open Access Journals (Sweden)

    Jeremy Koster

    Full Text Available For individuals, status is derived both from their personal attributes and the groups with whom they are affiliated. Depending on the performance of their groups, the status of individuals may benefit or suffer from identifying closely with the group. When the group excels, high-status members potentially receive much of the credit and increased status. Conversely, high-status members of underperforming groups potentially suffer disproportionate declines in their status relative to the low-status group members. We therefore predict an interaction between group performance and individual status on the willingness to associate with the group and its members. We test our prediction by examining social media ties among teammates in the National Basketball Association. Specifically, we investigate the "following" ties of teammates on Twitter at the end of the 2014-2015 season. Elections to All-Star games are used to measure the status of players, and team performance is measured by recent success in the postseason playoffs. The results show that compared to high-status players on successful teams, high-status players on underperforming teams are less likely to follow their teammates. This result aligns with research on status inconsistency, suggesting that individuals deemphasize their group affiliation when it jeopardizes their individual status. An additional contribution is the advancement of the probit Social Relations Model for the analysis of binary ties in social networks.

  5. The effects of individual status and group performance on network ties among teammates in the National Basketball Association.

    Science.gov (United States)

    Koster, Jeremy; Aven, Brandy

    2018-01-01

    For individuals, status is derived both from their personal attributes and the groups with whom they are affiliated. Depending on the performance of their groups, the status of individuals may benefit or suffer from identifying closely with the group. When the group excels, high-status members potentially receive much of the credit and increased status. Conversely, high-status members of underperforming groups potentially suffer disproportionate declines in their status relative to the low-status group members. We therefore predict an interaction between group performance and individual status on the willingness to associate with the group and its members. We test our prediction by examining social media ties among teammates in the National Basketball Association. Specifically, we investigate the "following" ties of teammates on Twitter at the end of the 2014-2015 season. Elections to All-Star games are used to measure the status of players, and team performance is measured by recent success in the postseason playoffs. The results show that compared to high-status players on successful teams, high-status players on underperforming teams are less likely to follow their teammates. This result aligns with research on status inconsistency, suggesting that individuals deemphasize their group affiliation when it jeopardizes their individual status. An additional contribution is the advancement of the probit Social Relations Model for the analysis of binary ties in social networks.

  6. The Effects of Solo Status on Women's and Men's Success: The Moderating Role of the Performance Context

    Science.gov (United States)

    Viallon, Marie-Laure; Martinot, Delphine

    2009-01-01

    A considerable body of research has shown that being the only representative of one's gender group (solo status) when performing an activity affects women more than men. The aim of our two experiments was to show that the performance context can moderate the effects of numerical status (majority vs. solo) on performance and that men can also be…

  7. Adolescent Weight Status and Self-Reported School Performance in South Korea

    Directory of Open Access Journals (Sweden)

    Young Kyung Do

    2011-01-01

    Full Text Available Using a nationally representative sample of 142 783 middle school (13–15 years old and high school (16–18 years old students in South Korea, this study examined whether (1 overweight and obesity are more likely to be associated with lower self-reported school performance; (2 overweight and obese students are more likely to enrol in a vocational high school as opposed to a general high school; (3 the association between obesity and poorer self-reported school performance is mediated through body image stress and health status. We found that excess weight was negatively associated with self-reported school performance among middle and general high school students, and that obese students had a higher probability of being enrolled in a vocational over a general high school. We did not find strong evidence on the mediating role of body image stress and health status.

  8. Performance analysis of spectrum sensing with multiple status changes in primary user traffic

    KAUST Repository

    Tang, Liang

    2012-06-01

    In this letter, the impact of primary user traffic with multiple status changes on the spectrum sensing performance is analyzed. Closed-form expressions for the probabilities of false alarm and detection are derived. Numerical results show that the multiple status changes of the primary user cause considerable degradation in the sensing performance. This degradation depends on the number of changes, the primary user traffic model, the primary user traffic intensity and the signal-to-noise ratio of the received signal. Numerical results also show that the amount of degradation decreases when the number of changes increases, and converges to a minimum sensing performance due to the limited sensing period and primary holding time. © 2012 IEEE.

  9. Watertrak, a computerized liquid waste treatment system status and performance monitoring program

    International Nuclear Information System (INIS)

    Vance, J.N.; Tafazzoli, M.M.

    1984-01-01

    Because of continuing problems in the radwaste system operations of a large number of plants currently operating, there is an increasing need to provide greater quantities of radwaste system information to plant operators and managers. Current and more complete information is required to enhance the operation and performance of the radwaste treatment systems, to assess the current system status, to plan for changing plant conditions and to diagnose actual or impending problems. The information needs include: real-time system status monitoring, equipment performance monitoring, report generation for operators and plant management, and training information. The nature and quantity of information required makes this program well-suited for a computer-aided engineering application

  10. The effect of breed type and lactation status on reproductive performance in Awassi ewes

    OpenAIRE

    Kridli, R.T.; Abdullah, A.Y.; Husein, M.Q.

    2009-01-01

    This study was conducted to evaluate the effect of breed types and lactation status on reproductive performance of hormonally-treated Awassi ewes. A total of 282 ewes were treated with intravaginal progestagen sponges and equine chorionic gonadotropin. Ewes were mated with fertile rams following sponge removal. Lambing rate was similar between brown-and black-faced ewes, while the percentage of multiple births, fecundity and prolificacy were greater in black-faced ewes. Lambing rate and the p...

  11. ATLAS Physics Objects Status and Performance at 13 TeV

    CERN Document Server

    Riu, Imma; The ATLAS collaboration

    2015-01-01

    Important for physics analyses is the understanding and commissioning of physics objects. A first look at the 13 TeV data has proved a reasonably good Monte Carlo modelling of the objects and they have been used for first physics measurements and searches beyond the Standard Model. This talk is to be given at the Top Workshop and provides an overview of the status and performance of the physics objects with the early 13 TeV data taken in summer 2015.

  12. CDC's Prevention Status Reports: Monitoring the Status of Public Health Policies and Practices for Improved Performance and Accountability.

    Science.gov (United States)

    Young, Andrea C; Lowry, Garry; Mumford, Karen; Graaf, Christine

    Increasing the adoption and implementation of evidence-based policies and practices is a key strategy for improving public health. Although there is widespread agreement about the importance of implementing evidence-based public health policies and practices, there are gaps between what has been shown to be effective and what is implemented at the state level. The Centers for Disease Control and Prevention (CDC) developed the Prevention Status Reports (PSRs), a performance measurement system, to highlight evidence-based public health policies and practices and catalyze state performance and quality improvement efforts across the nation. CDC selected a set of 10 topics representing some of the most important public health challenges in the nation. Stakeholders, including state health departments and other partners, helped conceptualize the PSRs and informed the development of the PSR framework, which provides an organizational structure for the system. CDC subject matter experts developed criteria for selecting policies and practices, indicators for each policy and practice, and a criteria-based rating system for each indicator. The PSRs were developed for all 50 states and the District of Columbia. The PSRs were developed and serve as a performance measurement system for monitoring the adoption, reach, and implementation fidelity of evidence-based public health policies and practices nationwide. The PSRs include 33 policy and practice indicators across the 10 health topics. They use a simple 3-level rating system-green, yellow, and red-to report the extent to which each state (and the District of Columbia) has implemented the policy or practice in accordance with supporting evidence or expert recommendations. Results from aggregate analyses show positive change or improvement. The PSRs are a unique part of CDC's work to improve the performance and accountability of the public health system, serving as both a monitoring tool and a call to action to improve health

  13. Food provisioning and parental status in songbirds: can occupancy models be used to estimate nesting performance?

    Directory of Open Access Journals (Sweden)

    Aude Catherine Corbani

    Full Text Available Indirect methods to estimate parental status, such as the observation of parental provisioning, have been problematic due to potential biases associated with imperfect detection. We developed a method to evaluate parental status based on a novel combination of parental provisioning observations and hierarchical modeling. In the summers of 2009 to 2011, we surveyed 393 sites, each on three to four consecutive days at Forêt Montmorency, Québec, Canada. We assessed parental status of 2331 adult songbirds based on parental food provisioning. To account for imperfect detection of parental status, we applied MacKenzie et al.'s (2002 two-state hierarchical model to obtain unbiased estimates of the proportion of sites with successfully nesting birds, and the proportion of adults with offspring. To obtain an independent evaluation of detection probability, we monitored 16 active nests in 2010 and conducted parental provisioning observations away from them. The probability of detecting food provisioning was 0.31 when using nest monitoring, a value within the 0.11 to 0.38 range that was estimated by two-state models. The proportion of adults or sites with broods approached 0.90 and varied depending on date during the sampling season and year, exemplifying the role of eastern boreal forests as highly productive nesting grounds for songbirds. This study offers a simple and effective sampling design for studying avian reproductive performance that could be implemented in national surveys such as breeding bird atlases.

  14. Effect of iodine status and other nutritional factors on psychomotor and cognitive performance of Filipino schoolchildren.

    Science.gov (United States)

    Amarra, Ma Sofia V; Bongga, Demetria C; Peñano-Ho, Leticia; Cruz, Federico B; Solis, José S; Barrios, Erniel B

    2007-03-01

    Until 1998, iodine deficiency was a public health problem in the Philippines. A law entitled "An Act Promoting Salt Iodization Nationwide" (ASIN) has been passed and implemented by the government to eliminate iodine deficiency. The contribution of salt iodization, as well as dietary, health, and environmental factors, to improving the intellectual performance of Filipino schoolchildren remains to be determined. The objectives of the study were to determine the relationship between iodine status and levels of psychomotor and cognitive performance in first-grade children aged 6 to 10 years, and to examine the extent to which dietary, biochemical, health, and environmental factors contribute to children's mental performance. Two hundred ninety children in six classroom sections from a public school in Manila were examined by measurement of urinary iodine excretion (UIE) and thyroid palpation. The median UIE level for each section was determined. Sixty-five children classified as iodine deficient (UIE 100 microg/L without goiter, n = 31) were given psychomotor and cognitive function tests (Bender-Gestalt and Raven's Colored Progressive Matrices). Scores from the two tests were used to determine each child's general ability percentile rank. Other variables examined were dietary intake (% RDA of nutrients ingested based on two nonconsecutive 24-hour recalls); deficiencies in iron, vitamin A, and selenium; parasitic infection; coliform contamination of drinking water; household use of iodized salt; illness in the past 2 weeks; and wasting and stunting. Children whose general ability scores were at or above the 50th percentile had higher UIE levels, but the relationship was not significant. Children from sections with higher median UIE levels had higher percentile ranks for general ability (p = .002). Backward logistic regression showed that the variance in deficient and adequate mental performance was explained by dietary intakes that met > or = 80% of the RDA for energy

  15. Effect of dietary antioxidants, training, and performance correlates on antioxidant status in competitive rowers.

    Science.gov (United States)

    Braakhuis, Andrea J; Hopkins, Will G; Lowe, Timothy E

    2013-09-01

    The beneficial effects of exercise and a healthy diet are well documented in the general population but poorly understood in elite athletes. Previous research in subelite athletes suggests that regular training and an antioxidant-rich diet enhance antioxidant defenses but not performance. To investigate whether habitual diet and/or exercise (training status or performance) affect antioxidant status in elite athletes. Antioxidant blood biomarkers were assessed before and after a 30-min ergometer time trial in 28 male and 34 female rowers. The antioxidant blood biomarkers included ascorbic acid, uric acid, total antioxidant capacity (TAC), erythrocyte- superoxide dismutase, glutathione peroxidase (GPx), and catalase. Rowers completed a 7-d food diary and an antioxidant-intake questionnaire. Effects of diet, training, and performance on resting biomarkers were assessed with Pearson correlations, and their effect on exercise-induced changes in blood biomarkers was assessed by a method of standardization. With the exception of GPx, there were small to moderate increases with exercise for all markers. Blood resting TAC had a small correlation with total antioxidant intake (correlation .29; 90% confidence limits, ±.27), and the exercise-induced change in TAC had a trivial to small association with dietary antioxidant intake from vitamin C (standardized effect .19; ±.22), vegetables (.20; ±.23), and vitamin A (.25; ±.27). Most other dietary intakes had trivial associations with antioxidant biomarkers. Years of training had a small inverse correlation with TAC (-.32; ±.19) and a small association with the exercise-induced change in TAC (.27; ±.24). Training status correlates more strongly with antioxidant status than diet does.

  16. Upper gastrointestinal symptoms in patients with advanced cancer: relationship to nutritional and performance status.

    Science.gov (United States)

    Bovio, G; Montagna, G; Bariani, C; Baiardi, P

    2009-10-01

    The goals of the study were to determine the relationship of upper gastrointestinal symptoms with nutritional status and to assess their association with performance status in patients with advanced cancer. We studied 143 patients (50 F, 93 M, mean age 68 +/- 11 years, mean body mass index 22.39 +/- 4.3 kg/m(2)). Assessed symptoms were the following: anorexia, nausea, vomiting, dysphagia for solids, dysphagia for liquids, xerostomia, hypogeusia, dysgeusia, hiccup and chewing disturbances. We determined anthropometric parameters, daily energy intake and serum albumin, prealbumin and transferrin. The most common upper gastrointestinal symptoms were xerostomia (73%), anorexia (49%) and chewing disturbances (40%). Fifty-four percent of patients had weight loss greater than 10%. Seventy-three patients (51%) had daily energy intake lower than their resting energy expenditure. Mean serum prealbumin, albumin and transferrin were below normal range. Mean Eastern Cooperative Oncology Group performance status scale was 3.1 +/- 0.49. Symptoms were often strongly correlated, and usually, patients experienced at least three upper gastrointestinal symptoms at the same time. Anorexia, nausea and vomiting were the symptoms mostly correlated with other symptoms. A correlation was found between vomiting and hiccup. Energy intake (EI) was the nutritional parameter mostly affected by upper gastrointestinal symptoms; moreover, EI is the most predictive factor of upper gastrointestinal symptoms, particularly xerostomia, anorexia and dysphagia for solids. Upper gastrointestinal symptoms are linked to nutritional parameters: In particular, energy intake represents the most predictive variable of symptom occurrence. The performance status is not affected by upper gastrointestinal symptoms. A rigorous nutritional assessment and the managing of upper gastrointestinal symptoms are crucial in patients with advanced cancer.

  17. Second-line Treatment of Stage III/IV Non-Small-Cell Lung Cancer (NSCLC with pemetrexed in routine clinical practice: Evaluation of performance status and health-related quality of life

    Directory of Open Access Journals (Sweden)

    Schuette Wolfgang

    2012-01-01

    Full Text Available Abstract Background Second-line treatment of advanced non-small-cell lung cancer (NSCLC improves overall survival. There is a lack of data regarding the impact on patients' overall health condition. This prospective, non-interventional study evaluated performance status (PS and health-related quality of life (HR-QoL during second-line pemetrexed treatment in routine clinical practice. Methods Stage III/IV NSCLC patients who initiated second-line pemetrexed (standard vitamin and dexamethasone supplementation were observed for a maximum of 9 treatment cycles. The primary objective was to evaluate the proportion of patients achieving improvement of Karnofsky Index (KI of ≥ 10% (absolute or maintaining KI ≥ 80% after the second treatment cycle ("KI benefit response". HR-QoL was self-rated using the EuroQoL-5D questionnaire (EQ-5D. Factors potentially associated with KI benefit response were evaluated using logistic regression models. Results Of 521 eligible patients (73.5% Stage IV, median age 66.3 yrs, 36.1% ≥ 70 yrs, 62.0% with KI ≥ 80%, 471 (90.4% completed at least 2 treatment cycles. 58.0% (95%CI 53.6%;62.2% achieved KI benefit response after the second cycle. Patients with baseline KI ≥ 80%, no Grade 3/4 toxicities during the first 2 cycles, or combination regimen as prior first-line therapy were more likely to achieve a KI benefit response. EQ-5D scores improved over time. Grade 3/4 toxicities were reported in 23.8% of patients (mainly fatigue/asthenia 15.9%, neutropenia 8.7%. Conclusions In this large prospective, non-interventional study of second-line pemetrexed treatment in patients with advanced NSCLC, including 36% elderly patients ( ≥ 70 years, physician-rated PS and self-rated HR-QoL were maintained or improved in the majority of patients. Trial registration Registered on ClinicalTrials.gov (NCT00540241 on October 4, 2007

  18. The development and status of performance assessment in radioactive waste disposal

    International Nuclear Information System (INIS)

    McCombie, C.; Papp, T.; Coplan, S.

    1990-01-01

    The development of formal performance assessment in radioactive waste disposal has been in progress for around 10-15 years now. The time is particularly opportune for a review of the state-of-the-art because of current changes in the status of repository planning and implementation worldwide. Several major feasibility-type studies have been completed, the first full site-specific safety analyses are being performed for engineered underground disposal facilities for L/ILW, and - for HLW - the die are now being cast by implementers and regulatory determining how the safety analyses for licensing are to be performed and assessed. The article reviews the development of performance assessment and attempts to identify some key issues occupying safety analysts and regulatory reviewers involved in waste disposal today. (author) 7 figs

  19. Hospital nurse job attitudes and performance: the impact of employment status.

    Science.gov (United States)

    Chu, Cheng-I; Hsu, Yao-Feng

    2011-03-01

    According to the 2007 Taiwan Labor Front Human Resources Report, as much as 47.6% of nurses at some public hospitals were contracted rather than full time. Furthermore, turnover rates for contract nurses were found to be as high as five to eight times of those for full-time nurses. Because high turnover rates are likely to induce negative impacts on the stability of care provided in the absence of staffing continuity, the association between nursing employment arrangement and nursing care quality is attracting greater attention. This study was designed to investigate the work status of contract versus full-time nurses at a public hospital in Taiwan and to examine the impact of such on work-related attitudes, organizational citizenship behavior, and job performance. Samples were recruited from a public hospital in Taiwan. In addition to self-rated items, researchers used supervisor-rated structured questionnaires for job performance to attenuate the possible effect of common method bias. The study investigated the impact of hospital nurse employment status on work-related attitudes, organizational citizenship behavior, and job performance using a regression model that included the critical work-related attitudes variables of job satisfaction and organizational commitment. Study findings included the following: (a) organizational commitment, job satisfaction, organizational citizenship behavior, and job performance correlate positively with one another. (b) No significant difference between contract and full-time nurses was found in terms of organizational commitment, job satisfaction, organizational citizenship behavior, and self-rated job performance. However, when rated by supervisors, reported job performance levels for full-time nurses were significantly higher than those of contract nurses. (c) Organizational citizenship behavior exhibited a mediating effect between job satisfaction, organizational commitment, and job performance. In this study, supervisors

  20. Effects of nutritional status on academic performance of Malaysian primary school children.

    Science.gov (United States)

    Zaini, M Z Anuar; Lim, C T; Low, W Y; Harun, F

    2005-01-01

    Numerous factors are known to affect the academic performance of students. These include prenatal conditions, birth conditions, postnatal events, nutritional, socio-economic factors and environmental factors. This paper examines the nutritional status and its relationship with academic performance of 9-10 years old primary school children recruited randomly in Selangor, Malaysia. A standard self-administered questionnaire was utilized to obtain pertinent information and a face-to-face interview was also conducted with the parents. Results of the academic performances were extracted from the students' report cards. The intellectual performance was assessed using Raven's Coloured Progressive Matrices. Physical examination was also conducted on these students by doctors. Overall 1,405 students and 1,317 parents responded to the survey. Of these 83.6% were Malays, 11.6% Indians, and 4.2% Chinese. The majority of them (82.9%) were from urban areas. The female: male ratio was 51:49; mean age was 9.71 years. The mean height and weight were 32.3 kg and 135.2 cm respectively. Their mean BMI was 17.42 kg/cm2, with 0.9% underweight, 76.3% normal BMI, 16.3% overweight, and 6.3% obese. Academic performance was significantly correlated with breast feeding, income and educational level of their parents, BMI, and whether they have been taking breakfast. There was a weak correlation between presence of anaemia and intellectual performance. Improving the socio-economic status of the parents will lend a helping hand in the academic performance of the students. Since breast feeding is associated with better academic and intellectual performance it must be emphasized, particularly to expectant mothers in the antenatal clinics.

  1. HEALTH INDICATORS IN SCHOOL: ASSESSMENT OF NUTRITIONAL STATUS AND MOTOR PERFORMANCE

    Directory of Open Access Journals (Sweden)

    Andressa Ribeiro Contreira

    2013-11-01

    Full Text Available Objective: This study aimed to investigate the relationship among motor performance and nutritional status in students. Methods: Attended by 27 adolescents of both sexes, aged between 11-13 years (average 11.74 ± 0.70 years from a private school in Florianópolis/SC. The motor performance was assessed using the MABC-2. For assess the nutritional status was used the BMI calculus. Results: Among 27 participants, 6 had a risk / indicative of motor difficulties and 9 had overweight. The vast majority of participants had adequate height for age. There was negative significant statistically correlation, but moderate, among BMI and total performance in the MABC-2, indicating that as higher the BMI, worse is the motor performance. Conclusion: Based on these results and the literature, it is suggested that in addition to the identification of children with overweight and motor difficulties, programs targeted physical activity and motor interventions are implemented, especially in the school environment, aiming to maintain the health conditions.

  2. Relationship Between the Functional Status Scale and the Pediatric Overall Performance Category and Pediatric Cerebral Performance Category Scales FREE

    Science.gov (United States)

    Pollack, Murray M.; Holubkov, Richard; Funai, Tomohiko; Clark, Amy; Moler, Frank; Shanley, Thomas; Meert, Kathy; Newth, Christopher J. L.; Carcillo, Joseph; Berger, John T.; Doctor, Allan; Berg, Robert A.; Dalton, Heidi; Wessel, David L.; Harrison, Rick E.; Dean, J. Michael; Jenkins, Tammara L.

    2015-01-01

    Importance Functional status assessment methods are important as outcome measures for pediatric critical care studies. Objective To investigate the relationships between the 2 functional status assessment methods appropriate for large-sample studies, the Functional Status Scale (FSS) and the Pediatric Overall Performance Category and Pediatric Cerebral Performance Category (POPC/PCPC) scales. Design, Setting, and Participants Prospective cohort study with random patient selection at 7 sites and 8 children’s hospitals with general/medical and cardiac/cardiovascular pediatric intensive care units (PICUs) in the Collaborative Pediatric Critical Care Research Network. Participants included all PICU patients younger than 18 years. Main Outcomes and Measures Functional Status Scale and POPC/PCPC scores determined at PICU admission (baseline) and PICU discharge. We investigated the association between the baseline and PICU discharge POPC/PCPC scores and the baseline and PICU discharge FSS scores, the dispersion of FSS scores within each of the POPC/PCPC ratings, and the relationship between the FSS neurologic components (FSS-CNS) and the PCPC. Results We included 5017 patients. We found a significant (P < .001) difference between FSS scores in each POPC or PCPC interval, with an FSS score increase with each worsening POPC/PCPC rating. The FSS scores for the good and mild disability POPC/PCPC ratings were similar and increased by 2 to 3 points for the POPC/PCPC change from mild to moderate disability, 5 to 6 points for moderate to severe disability, and 8 to 9 points for severe disability to vegetative state or coma. The dispersion of FSS scores within each POPC and PCPC rating was substantial and increased with worsening POPC and PCPC scores. We also found a significant (P < .001) difference between the FSS-CNS scores between each of the PCPC ratings with increases in the FSS-CNS score for each higher PCPC rating. Conclusions and Relevance The FSS and POPC/PCPC system

  3. Insights into Sexism: Male Status and Performance Moderates Female-Directed Hostile and Amicable Behaviour.

    Directory of Open Access Journals (Sweden)

    Michael M Kasumovic

    Full Text Available Gender inequality and sexist behaviour is prevalent in almost all workplaces and rampant in online environments. Although there is much research dedicated to understanding sexist behaviour, we have almost no insight into what triggers this behaviour and the individuals that initiate it. Although social constructionist theory argues that sexism is a response towards women entering a male dominated arena, this perspective doesn't explain why only a subset of males behave in this way. We argue that a clearer understanding of sexist behaviour can be gained through an evolutionary perspective that considers evolved differences in intra-sexual competition. We hypothesised that female-initiated disruption of a male hierarchy incites hostile behaviour from poor performing males who stand to lose the most status. To test this hypothesis, we used an online first-person shooter video game that removes signals of dominance but provides information on gender, individual performance, and skill. We show that lower-skilled players were more hostile towards a female-voiced teammate, especially when performing poorly. In contrast, lower-skilled players behaved submissively towards a male-voiced player in the identical scenario. This difference in gender-directed behaviour became more extreme with poorer focal-player performance. We suggest that low-status males increase female-directed hostility to minimize the loss of status as a consequence of hierarchical reconfiguration resulting from the entrance of a woman into the competitive arena. Higher-skilled players, in contrast, were more positive towards a female relative to a male teammate. As higher-skilled players have less to fear from hierarchical reorganization, we argue that these males behave more positively in an attempt to support and garner a female player's attention. Our results provide the clearest picture of inter-sexual competition to date, highlighting the importance of considering an evolutionary

  4. Insights into Sexism: Male Status and Performance Moderates Female-Directed Hostile and Amicable Behaviour.

    Science.gov (United States)

    Kasumovic, Michael M; Kuznekoff, Jeffrey H

    2015-01-01

    Gender inequality and sexist behaviour is prevalent in almost all workplaces and rampant in online environments. Although there is much research dedicated to understanding sexist behaviour, we have almost no insight into what triggers this behaviour and the individuals that initiate it. Although social constructionist theory argues that sexism is a response towards women entering a male dominated arena, this perspective doesn't explain why only a subset of males behave in this way. We argue that a clearer understanding of sexist behaviour can be gained through an evolutionary perspective that considers evolved differences in intra-sexual competition. We hypothesised that female-initiated disruption of a male hierarchy incites hostile behaviour from poor performing males who stand to lose the most status. To test this hypothesis, we used an online first-person shooter video game that removes signals of dominance but provides information on gender, individual performance, and skill. We show that lower-skilled players were more hostile towards a female-voiced teammate, especially when performing poorly. In contrast, lower-skilled players behaved submissively towards a male-voiced player in the identical scenario. This difference in gender-directed behaviour became more extreme with poorer focal-player performance. We suggest that low-status males increase female-directed hostility to minimize the loss of status as a consequence of hierarchical reconfiguration resulting from the entrance of a woman into the competitive arena. Higher-skilled players, in contrast, were more positive towards a female relative to a male teammate. As higher-skilled players have less to fear from hierarchical reorganization, we argue that these males behave more positively in an attempt to support and garner a female player's attention. Our results provide the clearest picture of inter-sexual competition to date, highlighting the importance of considering an evolutionary perspective when

  5. Is the technical performance of young soccer players influenced by hormonal status, sexual maturity, anthropometric profile, and physical performance?

    Science.gov (United States)

    Moreira, Alexandre; Massa, Marcelo; Thiengo, Carlos R; Rodrigues Lopes, Rafael Alan; Lima, Marcelo R; Vaeyens, Roel; Barbosa, Wesley P; Aoki, Marcelo S

    2017-12-01

    The aim of this study was to examine the influence of hormonal status, anthropometric profile, sexual maturity level, and physical performance on the technical abilities of 40 young male soccer players during small-sided games (SSGs). Anthropometric profiling, saliva sampling, sexual maturity assessment (Tanner scale), and physical performance tests (Yo-Yo and vertical jumps) were conducted two weeks prior to the SSGs. Salivary testosterone was determined by the enzyme-linked immunosorbent assay method. Technical performance was determined by the frequency of actions during SSGs. Principal component analyses identified four technical actions of importance: total number of passes, effectiveness, goal attempts, and total tackles. A multivariate canonical correlation analysis was then employed to verify the prediction of a multiple dependent variables set (composed of four technical actions) from an independent set of variables, composed of testosterone concentration, stage of pubic hair and genitalia development, vertical jumps and Yo-Yo performance. A moderate-to-large relationship between the technical performance set and the independent set was observed. The canonical correlation was 0.75 with a canonical R 2 of 0.45. The highest structure coefficient in the technical performance set was observed for tackles (0.77), while testosterone presented the highest structure coefficient (0.75) for the variables of the independent set. The current data suggest that the selected independent set of variables might be useful in predicting SSG performance in young soccer players. Coaches should be aware that physical development plays a key role in technical performance to avoid decision-making mistakes during the selection of young players.

  6. Predicting the outcomes of performance error indicators on accreditation status in the nuclear power industry

    International Nuclear Information System (INIS)

    Wilson, P.A.

    1986-01-01

    The null hypothesis for this study suggested that there was no significant difference in the types of performance error indicators between accredited and non-accredited programs on the following types of indicators: (1) number of significant event reports per unit, (2) number of forced outages per unit, (3) number of unplanned automatic scrams per unit, and (4) amount of equivalent availability per unit. A sample of 90 nuclear power plants was selected for this study. Data were summarized from two data bases maintained by the Institute of Nuclear Power Operations. Results of this study did not support the research hypothesis. There was no significant difference between the accredited and non-accredited programs on any of the four performance error indicators. The primary conclusions of this include the following: (1) The four selected performance error indicators cannot be used individually or collectively to predict accreditation status in the nuclear power industry. (2) Annual performance error indicator ratings cannot be used to determine the effects of performance-based training on plant performance. (3) The four selected performance error indicators cannot be used to measure the effect of operator job performance on plant effectiveness

  7. Status of Breast Self-Examination Performance among Women Referring to Health Centers of Tabriz, Iran

    Directory of Open Access Journals (Sweden)

    Farshbaf-Khalili Azizeh

    2014-07-01

    Full Text Available Objective: Breast cancer is the most common type of cancer and the second principal cause of deaths from cancer in women. Breast self-examination (BSE is an inexpensive screening method and is carried out by women themselves. The purpose of this study was to examine the status of breast self-examination performance among women referring to health centers of Tabriz, Iran. Materials and Methods: This study was a descriptive/ cross-sectional research carried out on 400 women aged 20-50 years. The samples were recruited randomly from among female clients of health centers in Tabriz. A questionnaire and an observational checklist were used to elicit socio-demographic information and status of BSE performance among women. Content validity was used for validation and Cronbach’s alpha was calculated (0.80 for reliability of instrument. Descriptive and inferential statistics were used to analyze data through SPSS software. Results: The findings of this research showed that only 18.8% of women performed BSE. Among them, 46.67% performed BSE monthly, and 40% at the end of menstruation. The initiation age of BSE in 77% was between 21-30 years of age. It is considerable that 54.7% of them had received no advice on BSE from physicians and midwives. The majority of women did not perform the various steps of BSE. The quality of this screening was very desirable in 2 (0.5 %, desirable in 5 (1.3%, average in 19 (4.8%, undesirable in 36 (9%, and very undesirable in 338 (84.5% women. Chi-square test showed a significant relationship between the quality of BSE performance and level of education, employment, breastfeeding quality, and family history of breast cancer (P < 0.05. Conclusion: The findings showed that the status of BSE performance was very poor. Therefore, to encourage women to use BSE correctly and regularly, education programs should be performed through various media including television, radio, and leaflets. The role of Health personnel in this

  8. Variations in Oncologist Recommendations for Chemotherapy for Stage IV Lung Cancer: What Is the Role of Performance Status?

    Science.gov (United States)

    Tisnado, Diana; Malin, Jennifer; Kahn, Katherine; Landrum, Mary Beth; Fletcher, Robert; Klabunde, Carrie; Clauser, Steven; Rogers, Selwyn O; Keating, Nancy L

    2016-07-01

    Chemotherapy prolongs survival in patients with advanced non-small-cell lung cancer. However, few studies have included patients with poor performance status. This study examined rates of oncologists' recommendations for chemotherapy by patient performance status and symptoms and how physician characteristics influence chemotherapy recommendations. We surveyed medical oncologists involved in the care of a population-based cohort of patients with lung cancer from the CanCORS (Cancer Care Outcomes Research and Surveillance) study. Physicians were queried about their likelihood to recommend chemotherapy to patients with stage IV lung cancer with varying performance status (Eastern Cooperative Oncology Group performance status 0 [good] v 3 [poor]) and presence or absence of tumor-related pain. Repeated measures logistic regression was used to estimate the independent associations of patients' performance status and symptoms and physicians' demographic and practice characteristics with chemotherapy recommendations. Nearly all physicians (adjusted rate, 97% to 99%) recommended chemotherapy for patients with good performance status, and approximately half (adjusted rate, 38% to 53%) recommended chemotherapy for patients with poor performance status (P factors, physician and practice characteristics were less strongly associated with chemotherapy recommendations in adjusted analyses. Strong consensus among oncologists exists for chemotherapy in patients with advanced non-small-cell lung cancer and good performance status. However, the relatively high rate of chemotherapy recommendations for patients with poor performance status despite the unfavorable risk-benefit profile highlights the need for ongoing work to define high-value care in oncology and to implement and evaluate strategies to align incentives for such care. Copyright © 2016 by American Society of Clinical Oncology.

  9. The Radiosurgical Treatment of Arteriovenous Malformations: Obliteration, Morbidities, and Performance Status

    International Nuclear Information System (INIS)

    Sun, Daniel Q.; Carson, Kathryn A.; Raza, Shaan M.; Batra, Sachin; Kleinberg, Lawrence R.; Lim, Michael; Huang, Judy; Rigamonti, Daniele

    2011-01-01

    Objective: This study examined the single-center treatment outcomes of arteriovenous malformations (AVMs) of the brain using stereotactic radiosurgery, with regard to obliteration, predictive factors, morbidities, and patient performance status. Patients and Methods: 127 patients were treated between 1990 and 2008 by use of linear accelerator or Gamma Knife. Their median age was 37 years, the median AVM volume was 7.3 cc (range, 0.014-113.13 cc), and the median follow-up duration was 42 months (range, 6-209 months). Forty-two percent of patients presented with intracranial hemorrhage, 31% received embolization, and 8% underwent prior resection. Thirty-one percent of patients received more than one round of radiosurgery. Results: 64% of patients had complete obliteration confirmed by magnetic resonance imaging or angiography. Positive predictors of obliteration included pretreatment hemorrhage (p = 0.042), smaller AVM volume (odds ratio = 1.25; 95% CI, 1.03-1.52), and larger marginal dose (odds ratio = 0.292; 95% CI, 0.100-0.820), whereas embolization (p < 0.001) was a negative predictor . The annual risk of hemorrhage after radiosurgery was 2.2%, and the risk of death as a result of hemorrhage was 0.6-1.3%. Eleven percent of patients reported new or worsened neurologic symptoms. Radiosurgery was effective in treating AVM-related headaches (p < 0.001) but did not improve the performance status of patients. Conclusions: Stereotactic radiosurgery is an effective tool in the treatment of AVMs and amelioration of AVM-related headaches, but it did not affect the patients' performance status. Factors affecting obliteration include prior hemorrhage, marginal dose, prior embolization, and AVM volume. Risk of hemorrhage persists in the latency period after radiosurgery, and it remains finite even after complete obliteration.

  10. Differences in eating behaviors and masticatory performances by gender and obesity status.

    Science.gov (United States)

    Park, Soojin; Shin, Weon-Sun

    2015-01-01

    This study aimed to determine whether there might be differences in masticatory performance and eating behaviors by gender and obesity status. Forty eight (24 males; 24 females) non-obese and pre-obese young adults were matched for age, gender, and dental health. Eating behaviors were assessed using the Three-Factor Eating Questionnaire (TFEQ), and chewing performance while eating 152g of boiled rice was measured using electromyography (EMG). Compared with non-obese participants, pre-obese participants had significantly higher levels of disinhibition according to the TFEQ (Pdifferent by gender but not by obesity status. Males had a greater bite size (Pobese) and chewing power (r=-0.581, Pobese and r=-0.446, Pobese) were negatively associated with disinhibition score. Results suggest that the effects of gender and, in part, obesity on eating responses may be explained as chewing performance. Therefore, gender-specific interventions and counseling aimed at slowing the rate of ingestion could be promising behavioral treatments for obese persons. Copyright © 2014 Elsevier Inc. All rights reserved.

  11. Annual Status Report (FY2016) Performance Assessment for the Environmental Restoration Disposal Facility

    Energy Technology Data Exchange (ETDEWEB)

    Casbon, M. A. [CH2M HILL Plateau Remediation Company, Richland, WA (United States); Nichols, W. E. [CH2M HILL Plateau Remediation Company, Richland, WA (United States)

    2017-03-15

    DOE O 435.1, Radioactive Waste Management, and DOE M 435.1-1, Radioactive Waste Management Manual, require that a determination of continued adequacy of the performance assessment (PA), composite analysis (CA), and disposal authorization statement (DAS) be made on an annual basis, and it must consider the results of data collection and analysis from research, field studies, and monitoring. Annual summaries of low-level waste (LLW) disposal operations must be prepared with respect to the conclusions and recommendations of the PA and CA, and a determination of the need to revise the PA or CA must be made. The annual summary requirement provides a structured approach for demonstrating the continued adequacy of the PA and CA in demonstrating a reasonable expectation that the performance objectives will be met. This annual summary addresses only the status of the Environmental Restoration Disposal Facility (ERDF) PA (CP-60089, Performance Assessment for the Environmental Restoration Disposal Facility, Hanford Site, Washington, formerly WCH-520 Rev. 1)1. The CA for ERDF is supported by DOE/RL-2016-62, Annual Status Report (FY 2016): Composite Analysis of Low Level Waste Disposal in the Central Plateau at the Hanford Site. The ERDF PA portion of the CA document is found in Section 3.1.4, and the ERDF operations portion is found in Section 3.3.3.2 of that document.

  12. Smoking status and cognitive performance among vocational school students in Beijing, China.

    Science.gov (United States)

    Hu, Pengjuan; Huang, Lili; Zhou, Shuang; Shi, Qiang; Xiao, Dan; Wang, Chen

    2018-02-01

    In countries where smoking is associated with lower socioeconomic status, smokers tend to perform worse on cognitive tasks than non-smokers. China is now undergoing a similar process with a recent study showing that there is a reduced cognitive performance in middle aged but not in elderly smokers. We examined the links between smoking status and cognitive functioning among vocational school students in Beijing, China. A total of 213 students aged 16-20 (98 smokers and 115 non-smokers) were recruited from three vocational schools in Beijing. Participants completed three subtests of Wechsler Adult Intelligence Scale (WAIS) (information, arithmetic, digit span) and Dysexecutive Questionnaire (DEX). Smokers also completed a cigarette smoking questionnaire and Fagerstrom Test of Nicotine Dependence (FTND). Smokers performed worse than non-smokers in tests of arithmetic and digit span forward (t = 4.25, 2.05, both P < .05). Scores on digit span backward did not differentiate smokers and non-smokers, but among smokers, the performance on this subtest was related to the age of starting smoking (r = 0.26, p < .001). Cognitive performance in smokers was not related to tobacco dependence or intensity of smoking. Compared to non-smokers, smokers had a higher total DEX score and higher scores on three of its five subscales (Inhibition, Knowing-doing dissociation and Social regulation, all p < .05). Another subscale, In-resistance, did not differentiate smokers and non-smokers, but differentiated smokers with lower and higher levels of nicotine dependence (t = -2.12, p < .05). Smokers performed worse on some cognitive tasks than non-smokers and scored higher on a questionnaire assessing executive dysfunction. Copyright © 2017. Published by Elsevier Ltd.

  13. Influence of socioeconomic status on trauma center performance evaluations in a Canadian trauma system.

    Science.gov (United States)

    Moore, Lynne; Turgeon, Alexis F; Sirois, Marie-Josée; Murat, Valérie; Lavoie, André

    2011-09-01

    Trauma center performance evaluations generally include adjustment for injury severity, age, and comorbidity. However, disparities across trauma centers may be due to other differences in source populations that are not accounted for, such as socioeconomic status (SES). We aimed to evaluate whether SES influences trauma center performance evaluations in an inclusive trauma system with universal access to health care. The study was based on data collected between 1999 and 2006 in a Canadian trauma system. Patient SES was quantified using an ecologic index of social and material deprivation. Performance evaluations were based on mortality adjusted using the Trauma Risk Adjustment Model. Agreement between performance results with and without additional adjustment for SES was evaluated with correlation coefficients. The study sample comprised a total of 71,784 patients from 48 trauma centers, including 3,828 deaths within 30 days (4.5%) and 5,549 deaths within 6 months (7.7%). The proportion of patients in the highest quintile of social and material deprivation varied from 3% to 43% and from 11% to 90% across hospitals, respectively. The correlation between performance results with or without adjustment for SES was almost perfect (r = 0.997; 95% CI 0.995-0.998) and the same hospital outliers were identified. We observed an important variation in SES across trauma centers but no change in risk-adjusted mortality estimates when SES was added to adjustment models. Results suggest that after adjustment for injury severity, age, comorbidity, and transfer status, disparities in SES across trauma center source populations do not influence trauma center performance evaluations in a system offering universal health coverage. Copyright © 2011 American College of Surgeons. Published by Elsevier Inc. All rights reserved.

  14. The influence of learning styles, enrollment status and gender on academic performance of optometry undergraduates.

    Science.gov (United States)

    Prajapati, Bhavna; Dunne, Mark; Bartlett, Hannah; Cubbidge, Robert

    2011-01-01

    This cross-sectional study was designed to determine whether the academic performance of optometry undergraduates is influenced by enrollment status, learning style or gender. Three hundred and sixty undergraduates in all 3 years of the optometry degree course at Aston University during 2008-2009 were asked for their informed consent to participate in this study. Enrollment status was known from admissions records. An Index of Learning Styles (http://www4.nscu.edu/unity/lockers/users/f/felder/public/Learning-Styles.html) determined learning style preference with respect to four different learning style axes; active-reflective, sensing-intuitive, visual-verbal and sequential-global. The influence of these factors on academic performance was investigated. Two hundred and seventy students agreed to take part (75% of the cohort). 63% of the sample was female. There were 213 home non-graduates (entrants from the UK or European Union without a bachelor's degree or higher), 14 home graduates (entrants from the UK or European Union with a bachelor's degree or higher), 28 international non-graduates (entrants from outside the UK or European Union without a bachelor's degree or higher) and 15 international graduates (entrants from outside the UK or European Union with a bachelor's degree or higher). The majority of students were balanced learners (between 48% and 64% across four learning style axes). Any preferences were towards active, sensing, visual and sequential learning styles. Of the factors investigated in this study, learning styles were influenced by gender; females expressed a disproportionate preference for the reflective and visual learning styles. Academic performance was influenced by enrollment status; international graduates (95% confidence limits: 64-72%) outperformed all other student groups (home non graduates, 60-62%; international non graduates, 55-63%) apart from home graduates (57-69%). Our research has shown that the majority of optometry students

  15. Reactivity Insertion Accident (RIA) Capability Status in the BISON Fuel Performance Code

    Energy Technology Data Exchange (ETDEWEB)

    Williamson, Richard L. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Folsom, Charles Pearson [Idaho National Lab. (INL), Idaho Falls, ID (United States); Pastore, Giovanni [Idaho National Lab. (INL), Idaho Falls, ID (United States); Veeraraghavan, Swetha [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-05-01

    One of the Challenge Problems being considered within CASL relates to modelling and simulation of Light Water Reactor LWR) fuel under Reactivity Insertion Accident (RIA) conditions. BISON is the fuel performance code used within CASL for LWR fuel under both normal operating and accident conditions, and thus must be capable of addressing the RIA challenge problem. This report outlines required BISON capabilities for RIAs and describes the current status of the code. Information on recent accident capability enhancements, application of BISON to a RIA benchmark exercise, and plans for validation to RIA behavior are included.

  16. Primary central nervous system lymphoma: age and performance status are more important than treatment modality

    International Nuclear Information System (INIS)

    Corry, June; Smith, Jennifer G.; Wirth, Andrew; Quong, George; Liew, Kuen Hoe

    1998-01-01

    Purpose: To assess prognostic factors and treatment modalities of patients with primary central nervous system lymphoma (PCNSL) in terms of response rates, patterns of failure and overall survival. Methods and Materials: Sixty-two patients presenting with PCNSL between 1982 and 1994 at Peter MacCallum Cancer Institute with no evidence of human immunodeficiency virus infection were included in the study. Their median age was 60 years; World Health Organisation (WHO) performance status was ≥2 in 85%. All patients were planned to receive whole brain irradiation; 7 also received spinal irradiation. The median planned dose to the target volume was 50.4 Gy. Twenty patients were planned to receive chemotherapy as well. Patients were followed up to June 20, 1995, giving a median follow-up for 14 surviving patients of 5.4 years, range 0.3 to 10.2 years. Results: The clinical response rate to treatment was 77% [95% confidence interval (CI) 65 to 87%]. The estimated median overall survival was 20.6 months (CI 12.4 to 33.4 months). On univariate analysis male gender, age <60 years, WHO performance status ≤1, treatment to the target volume ≥45 Gy, and treatment with additional chemotherapy, were associated with a significantly better overall survival (p < 0.05). On multivariate analysis only age and performance status remained significant prognostic variables. Relapse involved the central nervous system or cerebrospinal fluid (CSF) in all patients with known sites of relapse except three who had ocular relapse only. There was a low incidence of relapse in the initial brain site (23% of known cases) and a high incidence (50%) of CSF/spinal cord relapse. Of 48 deaths, 15 were related to initial or subsequent treatment. Conclusions: Patient outcome is strongly influenced by age and performance status. Studies suggesting better survival for patients treated with chemoradiation may reflect patient selection rather than treatment variables. Optimal management remains to be

  17. Health status and productive performance of somatic cell cloned cattle and their offspring produced in Japan.

    Science.gov (United States)

    Watanabe, Shinya; Nagai, Takashi

    2008-02-01

    Since the first somatic cell cloned calves were born in Japan in 1998, more than 500 cloned cattle have been produced by somatic cell nuclear transfer and many studies concerning cloned cattle and their offspring have been conducted in this country. However, most of the results have been published in Japanese; thus, the data produced in this country is not well utilized by researchers throughout the world. This article reviews the 65 reports produced by Japanese researchers (62 written in Japanese and 3 written in English), which employed 171 clones and 32 offspring, and categorizes them according to the following 7 categories: (1) genetic similarities and muzzle prints, (2) hematology and clinical chemistry findings, (3) pathology, (4) growth performance, (5) reproductive performance, (6) meat production performance and (7) milk production performance. No remarkable differences in health status or reproductive performance were found among conventionally bred cattle, somatic cell cloned cattle surviving to adulthood and offspring of somatic cell cloned cattle. Similarities in growth performance and meat quality were observed between nuclear donor cattle and their clones. The growth curves of the offspring resembled those of their full siblings.

  18. Cloud service performance evaluation: status, challenges, and opportunities – a survey from the system modeling perspective

    Directory of Open Access Journals (Sweden)

    Qiang Duan

    2017-05-01

    Full Text Available With rapid advancement of Cloud computing and networking technologies, a wide spectrum of Cloud services have been developed by various providers and utilized by numerous organizations as indispensable ingredients of their information systems. Cloud service performance has a significant impact on performance of the future information infrastructure. Thorough evaluation on Cloud service performance is crucial and beneficial to both service providers and consumers; thus forming an active research area. Some key technologies for Cloud computing, such as virtualization and the Service-Oriented Architecture (SOA, bring in special challenges to service performance evaluation. A tremendous amount of effort has been put by the research community to address these challenges and exciting progress has been made. Among the work on Cloud performance analysis, evaluation approaches developed with a system modeling perspective play an important role. However, related works have been reported in different sections of the literature; thus lacking a big picture that shows the latest status of this area. The objectives of this article is to present a survey that reflects the state of the art of Cloud service performance evaluation from the system modeling perspective. This articles also examines open issues and challenges to the surveyed evaluation approaches and identifies possible opportunities for future research in this important field.

  19. Comparing cognition, mealtime performance, and nutritional status in people with dementia with or without ideational apraxia.

    Science.gov (United States)

    Wu, Hua-Shan; Lin, Li-Chan

    2015-03-01

    To describe the prevalence rate of ideational apraxia (IA) affecting self-feeding in people with dementia, confirm the stage of dementia at which IA most commonly occurs, and compare mealtime performance and nutritional status between people with dementia (PWD) with and without IA. A cross-sectional design with between-subject comparison was used. Among the 395 potential participants recruited from dementia special care units at nine long-term care facilities in central and northern Taiwan, 98 met the operational definition of IA and were included in the PWD with IA group. From the remaining pool, 98 participants, matched for age and sex with the PWD with IA group, were randomly allocated to the PWD without IA group. Eating Behavior Scale (EBS) scores, food intake, total eating time, meal assistance, body mass index, Mini-Nutritional Assessment (MNA), and Mini-Mental State Examination scores were collected. The prevalence rate of IA affecting self-feeding in our study population of PWD was 24.8%. PWD with IA had significantly lower EBS scores, had more food intake (p performance and nutritional status. For PWD with IA, reassigning staff at mealtimes based on eating ability and providing memory training are recommended. © The Author(s) 2014.

  20. Removal of Endobronchial Malignant Mass by Cryotherapy Improved Performance Status to Receive Chemotherapy

    Science.gov (United States)

    Hsieh, Meng-Heng; Wang, Tsai-Yu; Yu, Chih-Teng; Chou, Chun-Liang; Lin, Shu-Min; Kuo, Chih-Hsi; Chung, Fu-Tsai

    2014-01-01

    Although malignant endobronchial mass (MEM) has poor prognosis, cryotherapy is reportedly a palliative treatment. Clinical data on postcryotherapy MEM patients in a university-affiliated hospital between 2007 and 2011 were evaluated. Survival curve with or without postcryotherapy chemotherapy and performance status (PS) improvement of these subjects were analyzed using the Kaplan-Meier method. There were 59 patients (42 males), with median age of 64 years (range, 51–76, and median performance status of 2 (interquartile range [IQR], 2-3). Postcryotherapy complications included minor bleeding (n = 12) and need for multiple procedures (n = 10), while outcomes were relief of symptoms (n = 51), improved PS (n = 45), and ability to receive chemotherapy (n = 40). The survival of patients with chemotherapy postcryotherapy was longer than that of patients without such chemotherapy (median, 534 versus 106 days; log-rank test, P = 0.007; hazard ratio, 0.25; 95% confidence interval, 0.10–0.69). The survival of patients with PS improvement postcryotherapy was longer than that of patients without PS improvement (median, 406 versus 106 days; log-rank test, P = 0.02; hazard ratio, 0.28; 95% confidence interval, 0.10–0.81). Cryotherapy is a feasible treatment for MEM. With better PS after cryotherapy, further chemotherapy becomes possible for patients to improve survival when MEM caused dyspnea and poor PS. PMID:25383370

  1. Doing better (or worse) than one's parents: Social status, mobility, and performance-avoidance goals.

    Science.gov (United States)

    Jury, Mickaël; Bruno, Alisée; Darnon, Céline

    2018-01-11

    Previous research has shown that, when succeeding in higher education, first-generation (FG) students endorse more performance-avoidance goals (i.e., the fear of performing poorly) than continuing-generation (CG) students. In this study, individual mobility is examined as a predictor of performance-avoidance goal endorsement. It is argued that FG students endorse more these goals than CG students because in higher education, the former (but not the latter) experience upward mobility. In addition, CG can also be at risk of endorsing these goals when they are confronted with downward mobility. Two studies were conducted with psychology students (N = 143 in Study 1; N = 176 in Study 2). In Study 1, FG and CG students' perceived upward mobility was measured. In Study 2, FG and CG students were provided with a feedback that suggested either upward or downward mobility. In both studies, participants reported their level of performance-avoidance goal endorsement. Results from Study 1 supported an indirect effect of status on performance-avoidance goals via a higher perception of upward mobility. Results from Study 2 supported that psychology students who face mobility (i.e., FG students who received better feedback than their usual level of performance, CG students who received worse feedback than their usual level of performance) increased their performance-avoidance goals the most. Taken together, the results of these studies support that one's actual social position and, even more, the social position one is about to reach are reliable predictors of performance-avoidance goals. © 2018 The British Psychological Society.

  2. The development and status of performance assessment in radioactive waste disposal

    International Nuclear Information System (INIS)

    McCombie, C.; Papp, T.; Coplan, S.

    1990-01-01

    The development of formal performance assessment in radioactive waste disposal has been in progress for around 10-15 years now. The time is particularly opportune for a review of the state-of-the-art because of current changes in the status of repository planning and implementation world-wide. Several major feasibility-type studies have been completed, the first full site-specific safety analyses are being performed for engineered underground disposal facilities for L/ILW, and - for HLW - the die are now being cast by implementers and regulators determining how the safety analyses for licensing are to be performed and assessed. This introductory paper reviews the development of performance assessment, including a reiteration of the aims and a recapitulation of the technical progress and achievements to date. The most important purpose, however, is to identify some key issues occupying safety analysts and regulatory reviewers involved in waste disposal today. The objective is to present the generally accepted consensus on the state of the art in performance assessment. 40 refs., 2 figs

  3. Children with minimal sensorineural hearing loss: prevalence, educational performance, and functional status.

    Science.gov (United States)

    Bess, F H; Dodd-Murphy, J; Parker, R A

    1998-10-01

    This study was designed to determine the prevalence of minimal sensorineural hearing loss (MSHL) in school-age children and to assess the relationship of MSHL to educational performance and functional status. To determine prevalence, a single-staged sampling frame of all schools in the district was created for 3rd, 6th, and 9th grades. Schools were selected with probability proportional to size in each grade group. The final study sample was 1218 children. To assess the association of MSHL with educational performance, children identified with MSHL were assigned as cases into a subsequent case-control study. Scores of the Comprehensive Test of Basic Skills (4th Edition) (CTBS/4) then were compared between children with MSHL and children with normal hearing. School teachers completed the Screening Instrument for Targeting Education Risk (SIFTER) and the Revised Behavior Problem Checklist for a subsample of children with MSHL and their normally hearing counterparts. Finally, data on grade retention for a sample of children with MSHL were obtained from school records and compared with school district norm data. To assess the relationship between MSHL and functional status, test scores of all children with MSHL and all children with normal hearing in grades 6 and 9 were compared on the COOP Adolescent Chart Method (COOP), a screening tool for functional status. MSHL was exhibited by 5.4% of the study sample. The prevalence of all types of hearing impairment was 11.3%. Third grade children with MSHL exhibited significantly lower scores than normally hearing controls on a series of subtests of the CTBS/4; however, no differences were noted at the 6th and 9th grade levels. The SIFTER results revealed that children with MSHL scored poorer on the communication subtest than normal-hearing controls. Thirty-seven percent of the children with MSHL failed at least one grade. Finally, children with MSHL exhibited significantly greater dysfunction than children with normal hearing

  4. Modalities for assessing the nutritional status in patients with diabetes and cancer.

    Science.gov (United States)

    Clemente, G; Gallo, M; Giorgini, M

    2018-05-30

    Epidemiological data have shown that an increased body mass index (BMI) is associated with a higher risk of various cancers, especially in obese diabetic patients. However, oncologic patients often present nutritional alterations that can worsen their prognosis. The aim of this review is to propose the use of cheaper and easy to use tools to assess the nutritional status of patients with cancer with altered glucose metabolism. Based on a literature review, we propose anthropometric measures to classify the degree of malnutrition. Moreover, the Karnofsky Performance Status (KPS) and the Eastern Cooperative Oncology Group's performance index (ECOG) are useful to assess the functional status of the body; the achievement of nutritional needs can be analysed with the PG-SGA questionnaire, while the quality of life can be investigated using the DTSQ, SF36, EQ-5D questionnaires and the Edmonton Symptom Assessment System. Pre-albumin dosage and lymphocyte count are proposed as nutritional parameters. The degree of hydration can be evaluated through the Bio-Impedance Test (BIA), and energy intake through the dairy food diary, which considers the type of nutrition and the consistency of the meals. It is possible to use a score for each tool used, which is useful to plan an adequate nutritional intervention. Copyright © 2018 Elsevier B.V. All rights reserved.

  5. Work status as a predictor of academic performance in the field of distance higher education

    Directory of Open Access Journals (Sweden)

    J. C. Welman

    2003-10-01

    Full Text Available This article reports on the academic success of 13 590 Technikon SA students and the importance of their "work status" (employed/unemployed in light of the co-operative education philosophy of technikons. The data was collected by means of the students’ registration records, and analysed using a CHAID-analysis. The results indicated that the variable "work status" features second last on the list of nine successful variables for predicting academic performance. Generally, it would appear that the employment practice for technikon students is not as important a requirement for academic success as the co-operative education philosophy would like it to be. Opsomming Hierdie artikel lewer verslag oor die akademiese sukses van 13 590 Technikon SA studente en die belangrikheid van hul “werkstatus” (werkend/werkloos in die lig van die koöperatiewe onderwysfilosofie van technikons. Die inligting wat deur middel van die studente se registrasierekords ingesamel is, is ontleed met ‘n CHAID-ontleding. Die resultate toon dat die veranderlike “werkstatus” tweede laaste op die lys van nege veranderlikes voorkom wat akademiese verrigting voorspel. Oor die algemeen blyk dit dat die indiensnemingpraktyk van technikonstudente nie so ‘n belangrike vereiste vir akademiese sukses is as wat die koöperatiewe onderwysfilosofie dit sou wou hê nie.

  6. Change in weight status and academic performance among senior high school students in Taiwan.

    Science.gov (United States)

    Liao, Pei-An; Chang, Hung-Hao; Wang, Jiun-Hao; Wu, Min-Chen

    2015-01-01

    This study examines how the changes in weight status across the spectrum of a senior high school study are associated with academic performance measured by the university entrance exam scores. A unique dataset which compiles a national health examination profile and the General Scholastic Ability Test data bank in Taiwan was constructed. The final sample comprised 149,240 senior high school students of which 70,662 were males and 78,578 were female students. The school-level fixed effect models were estimated. Students who were either (a) not overweight in the first year but overweight in the third year of senior high school, (b) overweight in both the first and third year, or (c) overweight in the first year but not overweight in the third year, were more likely to score lower on the university entrance exam, compared with their never-overweight counterparts. The findings differ by gender and test subjects. The change in weight status during senior high school period is associated with subsequent university entrance exam outcome. Students who start senior high school being overweight should be paid attention. School-based programs and practices need to be implemented to reduce the prevalence of overweight among students.

  7. Field performance assessment of synthetic liners for uranium tailings ponds: a status report

    International Nuclear Information System (INIS)

    Mitchell, D.H.; Spanner, G.E.

    1984-03-01

    The objective of this study is to provide a database to support US Nuclear Regulatory Commission (NRC) licensing of uranium tailings leachate isolation impoundments. This objective is being accomplished by determining the effectiveness of design, installation, and quality assurance practices associated with uranium mill tailings impoundments with flexible membrane liners. The program includes testing of chemical resistance and physical performance of liners, leak detection systems, and seam inspection techniques. This report presents the status of the program through September 1983. The report addresses impoundment design, installation, and inspection techniques used by the uranium milling industry. To determine the relative successes of these techniques, information has been collected from consultants, mill operators, and the synthetic liner industry. Progress in experimental tasks on chemical resistance of liners, physical properties of liners, and nondestructive examination of seams is reported. 25 references, 9 figures, 13 tables

  8. Treatment outcome in performance status 2 advanced NSCLC patients administered platinum-based combination chemotherapy

    DEFF Research Database (Denmark)

    Helbekkmo, Nina; Aasebø, Ulf; Sundstrøm, Stein H

    2008-01-01

    BACKGROUND: There is no consensus regarding chemotherapy to patients with advanced NSCLC (ANSCLC) and performance status (PS) 2. Using data from a national multicenter study comparing two third-generation carboplatin-based regimens in ANSCLC patients, we evaluated the outcome of PS 2 patients....... PATIENTS AND METHODS: The 123 PS 2 patients were compared to 309 PS 0/1 patients regarding survival, quality of life (QOL) and treatment toxicity. RESULTS: PS 2 patients had lower haemoglobin, lower global QOL and more pain, nausea/vomiting and dyspnea at inclusion. 68% of PS 2 patients received three...... chemotherapy courses vs. 85% in the PS 0/1 group (PPS 2 group, 4.5 vs. 8.9 months and 10% vs. 37% (PPS 2 patients needed blood transfusions (P=0.03) and hospitalization (PPS 2 patients had better relief of pain and dyspnea...

  9. Growth performance and oxidative status in piglets supplemented with verbascoside and teupolioside

    Directory of Open Access Journals (Sweden)

    G. Pastorelli

    2010-04-01

    Full Text Available Two hundred forty piglets, half female and half barrows, 8.1 ± 1.40 kg LW, were divided into 6 experimental groups and fed ad libitum with a diet supplemented with the following levels of antioxidants: 0 (CON + = positive control added with 100 mg lincomicine/kg, 5 (LT = low teupolioside or LV = low verbascoside, 10 (HT = high teupolioside; HV = high verbascoside; LT+LV mg/kg of diet for 56 days. Body weight and feed intake were recorded on d0, 14 and 56 of the trial. Ten piglets from each group were selected and blood collected by anterior vena cava puncture at 0, 14 and 56 d for reactive oxygen metabolite (ROMs determination. HV showed final weight higher than the other groups (P<0.05, and oxidative stability was improved by both integrations of verbascoside. These results support the view that Verbascoside influences the growth performances and oxidative status of piglets.

  10. Size ratio performance in detecting cerebral aneurysm rupture status is insensitive to small vessel removal.

    Science.gov (United States)

    Lauric, Alexandra; Baharoglu, Merih I; Malek, Adel M

    2013-04-01

    The variable definition of size ratio (SR) for sidewall (SW) vs bifurcation (BIF) aneurysms raises confusion for lesions harboring small branches, such as carotid ophthalmic or posterior communicating locations. These aneurysms are considered SW by many clinicians, but SR methodology classifies them as BIF. To evaluate the effect of ignoring small vessels and SW vs stringent BIF labeling on SR ruptured aneurysm detection performance in borderline aneurysms with small branches, and to reconcile SR-based labeling with clinical SW/BIF classification. Catheter rotational angiographic datasets of 134 consecutive aneurysms (60 ruptured) were automatically measured in 3-dimensional. Stringent BIF labeling was applied to clinically labeled aneurysms, with 21 aneurysms switching label from SW to BIF. Parent vessel size was evaluated both taking into account, and ignoring, small vessels. SR was defined accordingly as the ratio between aneurysm and parent vessel sizes. Univariate and multivariate statistics identified significant features. The square of the correlation coefficient (R(2)) was reported for bivariate analysis of alternative SR calculations. Regardless of SW/BIF labeling method, SR was equally significant in discriminating aneurysm ruptured status (P analysis of alternative SR had a high correlation of R(2) = 0.94 on the whole dataset, and R = 0.98 on the 21 borderline aneurysms. Ignoring small branches from SR calculation maintains rupture status detection performance, while reducing postprocessing complexity and removing labeling ambiguity. Aneurysms adjacent to these vessels can be considered SW for morphometric analysis. It is reasonable to use the clinical SW/BIF labeling when using SR for rupture risk evaluation.

  11. Records of performance and sanitary status from a dairy cattle herd in southern Brazil

    Directory of Open Access Journals (Sweden)

    Cláudio E. F. Cruz

    2011-01-01

    Full Text Available Over the last decades, the emphasis on the health of dairy cows has changed from an individual to a herd level. In this scenario, the role played by the recording system and its interpretation by veterinarians has gained primordial importance. The records of productive and reproductive performance and of sanitary status from a southern Brazilian dairy cattle herd have been presented and discussed. The period of study was 2000-2009. Mean values per lactation period were 349D 8436M 290F 275P 201SCS (D: days in lactation, M: kg of milk yield, F: kg of fat, P: kg of protein and SCS: somatic cell score in 1000 cells/ml of milk. Major indexes of reproductive efficiency included age at first calving (31 months, services per conception (2.1, intercalving interval (428 days, calving to conception interval (146 days, mean annual rates of parturitions (76.2%, fetal losses (9.8-19.0%, and stillbirths (3.6%, apart of voluntary waiting period (94 days. Main information on sanitary status of the herd was associated with the mean prevalence of common disorders of dairy cattle such as anaplasmosis (29.8%, mastitis (27.8%, digital diseases (26.3%, ovarian cysts (21.3%, placental retention (19.7%, postpartum uterine infections (10.6%, and calf diarrhea (23.7% and pneumonia (16.8%, among others. In addition, culling reasons (low reproductive performance [56.3%] and udder/mastitis problems [33.6%], causes of cattle deaths (anaplasmosis [16.4%] and leukosis [11.4], and the impact of cattle diseases such as tuberculosis, leukosis, and neosporosis on the herd have also been presented and succinctly discussed. Numbers between brackets represent rates accumulated in the 10-year period.

  12. Jump test performance and sarcopenia status in men and women, 55 to 75 years of age.

    Science.gov (United States)

    Singh, Harshvardhan; Kim, Daeyeol; Kim, Eonho; Bemben, Michael G; Anderson, Mark; Seo, Dong-Il; Bemben, Debra A

    2014-01-01

    Jumping mechanography uses maximal countermovement jumps to test obtain such as jump power (JPow). Recently, it has been shown to be a safe method for assessing muscle function in older adults; however, little is known about the relationships between JPow, muscle strength, and sarcopenia status. The purpose of this study was to examine jump performance, muscle strength, and sarcopenia status in older adults. This was a cross-sectional study that included men (n = 27) and women (n = 33) (55-75 years) recruited from the general community. Participants completed health status and physical activity questionnaires. Body composition, including appendicular skeletal muscle mass (ASM), bone free lean body mass, and relative skeletal muscle mass index, were assessed by total body dual-energy x-ray absorptiometry scans. The criteria for sarcopenia were relative skeletal muscle mass index values less than 7.26 kg/m2 for men and less than 5.45 kg/m2 for women. Three vertical jumps on a jump mat were performed to assess JPow, jump velocity (JVel), and jump height (JHt). Muscle strength was measured by 1RM testing for leg press (LP) and right and left hip abduction isotonic resistance exercises. Sarcopenia was found in 20% (12/60) of the participants. Jump power was significantly lower (P = .001) in the sarcopenia group than in the normal group, 651.1 (41.7) W versus 851.0 (27.4) W, respectively. Jump power and JHt were significantly (P mass. Significant (P muscle strength (LP, right and left hip abduction). The jump test protocol was conducted safely with no injuries or balance issues. Our finding of lower JPow in sarcopenic individuals adds new information to the existing literature on age-related declines in muscle power. Community-dwelling individuals classified as sarcopenic had significantly lower JPow but not muscle strength compared with their counterparts with normal amounts of muscle mass. Jump test variables were positively correlated with lean tissue and lower body

  13. Schoolteachers' awareness about scholastic performance and nutritional status of Egyptian schoolchildren.

    Science.gov (United States)

    Galal, Osman M; Ismail, Ibrahim; Gohar, Azza S; Foster, Zoë

    2005-06-01

    Malnutrition disorders affect more than 30% of schoolchildren in Egypt. This problem appears to be largely attributable to poor dietary quality and micronutrient deficiencies, such as iron and vitamin A. Inadequate nutrition intake has important implications because malnutrition has been shown to negatively affect the cognitive development of primary schoolchildren. This study assesses the awareness of schoolteachers about the impact of malnutrition on the scholastic performance of primary schoolchildren living in Egypt. Two focus group discussions were conducted with Egyptian schoolteachers from the Quena and Kharbia Governorates. The study indicates that schoolteachers consider low body weight and thinness as the primary signs of malnutrition. They do not prioritize malnutrition as a factor for poor scholastic performance. They also suggest that unhealthful eating habits, especially a lack of breakfast, negatively affect children's interaction with schoolteachers and their ability to excel in their studies. Schoolteachers endorse a more reliable and nutritionally valuable school-feeding program as a way to increase the scholastic performance of their students. The teachers advocate developing integrated programs between the Ministry of Education, the Ministry of Health and Population, teachers, children, and parents that provide nutrition education. A lack of awareness among teachers about the relationship of nutrition and cognitive function can lead to the misdiagnosis or delayed management of malnourished and scholastically challenged schoolchildren. This paper suggests that proper school-feeding programs and nutrition education programs, which integrate government ministries, teachers, children and parents, should be developed to improve the physical and cognitive health status of Egyptian schoolchildren.

  14. GRAPE EXTRACT IMPROVES ANTIOXIDANT STATUS AND PHYSICAL PERFORMANCE IN ELITE MALE ATHLETES

    Directory of Open Access Journals (Sweden)

    Sophie Lafay

    2009-09-01

    Full Text Available Excessive physical exercise overproduces reactive oxygen species. Even if elite sportsmen increase their antioxidant status by regular physical training, during the competition period, this improvement is not sufficient to limit free radical production which could be detrimental to the body. The aim of this randomized, double-blind, placebo controlled, and crossover study on 20 elite sportsmen (handball = 10, basketball = 5, sprint = 4, and volleyball = 1 during the competition period was to determine if the consumption of a grape extract (GE; Vitis vinifera L. was able to improve the parameters related to (i anti-oxidative status and oxidative stress and (ii physical performance. Specific biomarkers of antioxidant capacity, oxidative stress, skeletal cell muscle damage, and other general biomarkers were determined in plasma and urine before (D0 and after one month (D30 of placebo or GE supplementation (400mg·d-1. Effort tests were conducted using the Optojump® system, which allows determining the total physical performance (EnRJ45, explosive power (RJ110, and fatigue (RJL5. The plasma ORAC value was not modified in the placebo group; however, GE increased the ORAC value compared to the placebo at D30 (14 966+/-335 vs 14 242+/-339 µmol Teq·L-1; p < 0.05. The plasma FRAP value was significantly reduced in the placebo group, but not in the GE group. Therefore, GE limited the reduction of FRAP compared to the placebo at D30 (1 053.7+/-31.5 vs 993.7+/-26.7 µmol Teq·L-1; p < 0.05. Urinary isoprostane values were increased in the placebo group, but were not modified in the GE group. Consequently, GE limited the production of isoprostanes compared to the placebo at D30 (1.24+/-0.12 vs 1.26+/-0.13 ng·mg-1 creatinine; p < 0.05. GE administration, compared to the placebo at D30, reduced the plasmatic creatine phosphokinase concentration (CPK, 695.7+/-177.0 vs 480.0+/-81.1 IU·L-1, p = 0.1 and increased hemoglobin levels (Hb, 14.5+/-0.2 vs 14

  15. Direct and indirect relationships of physical fitness, weight status, and learning duration to academic performance in Japanese schoolchildren.

    Science.gov (United States)

    Ishihara, Toru; Morita, Noriteru; Nakajima, Toshihiro; Okita, Koichi; Yamatsu, Koji; Sagawa, Masato

    2018-03-01

    The purpose of this study was to determine, using structural equation modelling (SEM), the direct and indirect influence of daily behaviours (i.e. exercise/learning durations), weight status, and physical fitness on academic performance among seventh-grade schoolchildren, after controlling for socioeconomic status. We analysed cross-sectional data from 274 schoolchildren (159 males and 115 females; 12-13 years old). Academic performance was assessed using the total grade points in eight academic subjects. Physical fitness was evaluated using the total score of eight physical fitness tests and weight status using body mass index. The daily behaviours and socioeconomic status were assessed by the questionnaire. The SEM showed an adequate fit to the data (χ 2  = 0.684, p = .710, RMSEA = .000). Physical fitness and learning durations had direct effects on academic performance (β = .301, p academic performance via physical fitness. These findings suggest that, independent of socioeconomic status and learning durations, exercise habits and maintaining healthy weight status may indirectly contribute to academic success via better physical fitness in children.

  16. Early-1990 status of performance assessment for the Waste Isolation Pilot Plant disposal system

    Energy Technology Data Exchange (ETDEWEB)

    Bertram-Howery, S G [Sandia National Laboratories, Albuquerque, NM (United States); Swift, P N [Tech Reps Inc., Albuquerque, NM (United States)

    1991-07-15

    This paper summarizes the early-1990 status of the performance-assessment work being done to evaluate compliance of the Waste Isolation Pilot Plant with the U.S. Environmental Protection Agency regulation 40 CFR Part 191, Subpart B. This regulation sets environmental standards for radioactive waste disposal (Environmental Radiation Protection Standards for Management and Disposal of Spent Nuclear Fuel, High-Level and Transuranic Radioactive Wastes). As required by Subpart B, evaluations of compliance will include probabilistic numerical simulations of repository performance and qualitative judgments. Compliance appears uncertain only in the event of human intrusion into the repository after decommissioning. Issues affecting compliance following intrusion include properties of the plugs used to seal the intruding borehole, permeability and porosity of the waste, and possible pressurization of the repository by gas generated from the organic decomposition and corrosion of the waste and containers. Research is in progress to determine the probability of intrusion and to quantify parameter uncertainties needed to include these factors in simulations of repository performance. The Department of Energy (DOE) is following two strategies to assure compliance. First, passive marker systems will be designed and implemented to reduce the likelihood of intrusion and increase the likelihood that intruders will properly reseal the repository. Second, modifications to the form of the waste and the design of the repository to achieve acceptable performance if the intruding borehole is not adequately sealed will be designed. Goals include reductions in gas generation and waste permeability and porosity. Numerous modifications are technically possible. Work in progress will evaluate proposed modifications and recommend the most promising for further testing. The DOE is confident that compliance with Subpart B of 40 CFR 191 can be established using a combination of the two strategies

  17. Early-1990 status of performance assessment for the Waste Isolation Pilot Plant disposal system

    International Nuclear Information System (INIS)

    Bertram-Howery, S.G.; Swift, P.N.

    1991-07-01

    This paper summarizes the early-1990 status of the performance-assessment work being done to evaluate compliance of the Waste Isolation Pilot Plant with the U.S. Environmental Protection Agency regulation 40 CFR Part 191, Subpart B. This regulation sets environmental standards for radioactive waste disposal (Environmental Radiation Protection Standards for Management and Disposal of Spent Nuclear Fuel, High-Level and Transuranic Radioactive Wastes). As required by Subpart B, evaluations of compliance will include probabilistic numerical simulations of repository performance and qualitative judgments. Compliance appears uncertain only in the event of human intrusion into the repository after decommissioning. Issues affecting compliance following intrusion include properties of the plugs used to seal the intruding borehole, permeability and porosity of the waste, and possible pressurization of the repository by gas generated from the organic decomposition and corrosion of the waste and containers. Research is in progress to determine the probability of intrusion and to quantify parameter uncertainties needed to include these factors in simulations of repository performance. The Department of Energy (DOE) is following two strategies to assure compliance. First, passive marker systems will be designed and implemented to reduce the likelihood of intrusion and increase the likelihood that intruders will properly reseal the repository. Second, modifications to the form of the waste and the design of the repository to achieve acceptable performance if the intruding borehole is not adequately sealed will be designed. Goals include reductions in gas generation and waste permeability and porosity. Numerous modifications are technically possible. Work in progress will evaluate proposed modifications and recommend the most promising for further testing. The DOE is confident that compliance with Subpart B of 40 CFR 191 can be established using a combination of the two strategies

  18. Low vitamin D status is associated with reduced muscle mass and impaired physical performance in frail elderly people.

    Science.gov (United States)

    Tieland, M; Brouwer-Brolsma, E M; Nienaber-Rousseau, C; van Loon, L J C; De Groot, L C P G M

    2013-10-01

    Serum 25-hydroxyvitamin D (25(OH)D) status has been associated with muscle mass, strength and physical performance in healthy elderly people. Yet, in pre-frail and frail elderly people this association has not been studied. The objective of this study was to explore the association between vitamin D intake and serum 25(OH)D status with muscle mass, strength and physical performance in a pre-frail and frail elderly population. This cross-sectional study included 127 pre-frail and frail elderly people in The Netherlands. Whole body and appendicular lean mass (ALM) (dual energy X-ray absorptiometry), leg strength (one repetition maximum), handgrip strength and physical performance (short physical performance battery) were measured, and blood samples were collected for the assessment of serum 25(OH)D status (liquid chromatography-tandem mass spectrometry). In addition, habitual dietary intake (3-day food records) and physical activity data (accelerometers) were collected. In total, 53% of the participants had a serum 25(OH)D level below 50  nmol/l. After adjustment for confounding factors, 25(OH)D status was associated with ALM (β=0.012, P=0.05) and with physical performance (β=0.020, PVitamin D intake was associated with physical performance (β=0.18, P0.05). In this frail elderly population, 25(OH)D status is low and suggests a modest association with reduced ALM and impaired physical performance. In addition, vitamin D intake tended to be associated with impaired physical performance. Our findings highlight the need for well-designed intervention trials to assess the impact of vitamin D supplementation on 25(OH)D status, muscle mass and physical performance in pre-frail and frail elderly people.

  19. Solo status and self-construal: being distinctive influences racial self-construal and performance apprehension in African American women.

    Science.gov (United States)

    Sekaquaptewa, Denise; Waldman, Andrew; Thompson, Mischa

    2007-10-01

    A preliminary study and main experiment tested the hypothesis that racial solo status (being the only member of one's race in a group) increases racial self-construal among African Americans. The preliminary study showed that African American men and women reported greater collectivist (i.e., group-based) over individualist self-construal under solo compared to nonsolo status, whereas Whites did not. The main experiment showed that the increased collectivism among African American solo women appears to be strongly reflected in racial identity becoming a salient aspect of self-construal. African American participants were also more likely than Whites to perceive that their anticipated performance would be generalized to their race, to feel like representatives of their race, and to show greater performance apprehension (indirectly evidenced by increased self-handicapping) when in racial solo status. The implications of solo status for African Americans in evaluative situations (such as academic testing sessions) are discussed. 2007 APA

  20. Role of medicinal plants on growth performance and immune status in fish.

    Science.gov (United States)

    Awad, Elham; Awaad, Amani

    2017-08-01

    Disease outbreaks increase proportionally with increases in intensive aquaculture. Natural products including medicinal plants have been known from thousands of years for treating some human diseases. It is well known that many active compounds are responsible for potential bio-activities. For that reason, there has been considerable interest in the use of medicinal plants in aquaculture with a view to providing safe and eco-friendly compounds for replacing antibiotics and chemical compounds as well as to enhance immune status and control fish diseases. This article describes a wide range of medicinal plants such as herbs, seeds, and spices with different forms such as crude, extracts, mixed and active compounds, used as immunostimulants and resulting in a marked enhancement in the immune system of fish to prevent and control microbial diseases. Moreover, different activity was recorded from plant parts like seeds, roots, flowers and leaves. The mode of action of medicinal plants was stimulation of the cellular and humoral immune response which was monitored through elevation in immune parameters. Various levels of immune stimulation have been shown by medicinal plants at different concentrations through injection or immersion or oral administration. However, it is critically important to determine the optimal dose to enhance the immune system of fish and avoid the risk of immunosuppression. Some medicinal plants have been used to replace the protein in fishmeal as a cheap source of protein and proved to be efficient in this respect. Medicinal plants can act as a growth promoter and immunomodulator at the same time. Further investigations should be carried out to examine the influence of those plants on fish health (including physiological and histological parameters) as a preliminary step for use in large scale in aquaculture. The current review describes the role of medicinal plants and their derivatives on innate and adaptive immune status as well as growth

  1. Nutritional status and cognitive performance of mother-child pairs in Sidama, Southern Ethiopia.

    Science.gov (United States)

    Bogale, Alemtsehay; Stoecker, Barbara J; Kennedy, Tay; Hubbs-Tait, Laura; Thomas, David; Abebe, Yewelsew; Hambidge, K Michael

    2013-04-01

    The purpose of this study was to assess the nutritional status and cognitive performance of women and their 5-year-old children using a cross-sectional design. Cognitive performance of mothers and children was assessed with Raven's Colored Progressive Matrices (CPM) and Kaufman Assessment Battery for Children-II (KABC-II). Demographic characteristics, food consumption patterns and anthropometry were also measured. Four rural districts in Sidama, southern Ethiopia served as the setting for this study. Subjects were one hundred women and their 5-year-old children. Mean ± standard deviation age of the mothers was 29 ± 6 years and family size was 7.0 ± 2.6. Maternal body mass index (BMI) ranged from 15.3 to 29.0 with 14% of the mothers having BMI children revealed 29% to be stunted (height-for-age z-score education significantly contributed to prediction of both mothers' and children's cognitive test scores. There were significant differences in mean cognitive test scores between stunted and non-stunted, and between underweight and normal-weight children. Height-for-age z-scores were correlated with scores for short-term memory (r = 0.42, P children with growth deficits suggesting that efficient and cost effective methods to alleviate malnutrition and food insecurity would impact not only child health but also cognitive function. © 2011 Blackwell Publishing Ltd.

  2. Impact of Multi-Micronutrient-Fortified Rice on Micronutrient Status, Health, and Cognitive Performance in Schoolchildren in Cambodia

    DEFF Research Database (Denmark)

    Khov, Kuong

    ferritin concentrations nutritional status of school-age children as well as the reasons of iron deficiency. Food fortification...... with multiple micronutrients has the potential to improve micronutrient status, growth and cognitive performance, and reduce morbidity incidence in developing countries. In Cambodia, rice is a staple food, and therefore fortified rice with multiple micronutrients could be a promising strategy to reduce...... the prevalence of micronutrient deficiencies. However, few studies have investigated the impact of fortified rice on micronutrient status, health and cognitive development in school-age children. Therefore, the aim of this PhD study is to evaluate the impact of fortified rice on nutritional status, health...

  3. Evaluation of mid- and long-term consequences, clinical and social performance in Chernobyl acute radiation syndrome patients in a multi-centre clinical follow-up study

    International Nuclear Information System (INIS)

    Weiss, M.; Fischer, B.; Fliedner, T.M.; Bebeshko, V.G.; Belyi, D.A.; Kovalenko, A.N.; Nadejina, N.M.; Galstian, I.A.

    1996-01-01

    Since the Chernobyl accident in 1986 nearly all survivors (n=199) of 237 patients with suspected acute radiation syndrome (ARS) underwent regular follow-up investigations in the scientific centres in Kiev and in Moscow. In a close collaboration with these centres we investigate the health status of this population in a five step approach. An integral part of this approach to patient evaluation and analysis of the mid- and long-term consequences of the Chernobyl accident is a 'Questionnaire for clinical, laboratory and functional follow-up of radiation-exposed persons', developed with these centres. Beyond this project we report as an interim some results of analyses performed by the scientific centers in Kiev and in Moscow about disorders of the cardiovascular system and the digestive tract, formation of cataract, generalized and local skin injuries and/or disorders as well as for a subpopulation (n=89) the Karnofsky performance score and working ability

  4. Status and performance of the CALorimetric Electron Telescope (CALET) on the International Space Station

    Energy Technology Data Exchange (ETDEWEB)

    Adriani, O. [University of Florence, IFAC (CNR) and INFN (Italy); Akaike, Y. [ICRR, University of Tokyo (Japan); Asaoka, Y. [Waseda University (Japan); Asano, K. [Tokyo Institute of Technology (Japan); Bagliesi, M.G.; Bigongiari, G. [University of Siena and INFN (Italy); Binns, W.R. [Washington University-St. Louis (United States); Bongi, M. [University of Florence, IFAC (CNR) and INFN (Italy); Buckley, J.H. [Washington University-St. Louis (United States); Cassese, A.; Castellini, G. [University of Florence, IFAC (CNR) and INFN (Italy); Cherry, M.L. [Louisiana State University (United States); Collazuol, G. [University of Padova and INFN (Italy); Ebisawa, K. [JAXA/ISAS (Japan); Di Felice, V. [University of Rome Tor Vergata and INFN (Italy); Fuke, H. [JAXA/ISAS (Japan); Guzik, T.G. [Louisiana State University (United States); Hams, T. [CRESST/NASA/GSFC and University of Maryland (United States); Hasebe, N. [Waseda University (Japan); Hareyama, M. [St. Marianna University School of Medicine (Japan); and others

    2014-11-15

    The CALorimetric Electron Telescope (CALET) space experiment, currently under development by Japan in collaboration with Italy and the United States, will measure the flux of cosmic-ray electrons (including positrons) to 20 TeV, gamma rays to 10 TeV and nuclei with Z=1 to 40 up to 1,000 TeV during a two-year mission on the International Space Station (ISS), extendable to five years. These measurements are essential to search for dark matter signatures, investigate the mechanism of cosmic-ray acceleration and propagation in the Galaxy and discover possible astrophysical sources of high-energy electrons nearby the Earth. The instrument consists of two layers of segmented plastic scintillators for the cosmic-ray charge identification (CHD), a 3 radiation length thick tungsten-scintillating fiber imaging calorimeter (IMC) and a 27 radiation length thick lead-tungstate calorimeter (TASC). CALET has sufficient depth, imaging capabilities and excellent energy resolution to allow for a clear separation between hadrons and electrons and between charged particles and gamma rays. The instrument will be launched to the ISS within 2014 Japanese Fiscal Year (by the end of March 2015) and installed on the Japanese Experiment Module-Exposed Facility (JEM-EF). In this paper, we will review the status and main science goals of the mission and describe the instrument configuration and performance.

  5. Patients who die during palliative radiotherapy. Status survey

    International Nuclear Information System (INIS)

    Berger, B.; Ankele, H.; Bamberg, M.; Zips, D.

    2014-01-01

    Palliative radiotherapy (RT) is routinely used in end of life care of patients with advanced malignancies; however, unnecessarily burdensome treatment shortly before death should be avoided. There is little knowledge on incidence and causes of intercurrent deaths during palliative RT. In this study death events among inpatients receiving palliative RT between January 2009 and December 2011 at this department were retrospectively analyzed. Among epidemiological factors, treatment schedule and chronology, latency and duration of treatment in relation to the actual survival were identified. In this study 52 patients died during or shortly after palliative RT. Symptomatic bone metastases and brain metastases represented the most common RT indications. The general health status was poor with a median Karnofsky performance score of 50 %, RT was realized with a median single dose of 2.5 Gy to a median total dose of 30.5 Gy and was stopped prematurely in 73 % of patients. On average 53 % of the remaining lifetime was occupied by latency to starting RT. Once RT was begun the treatment duration required a median 64 % of the still remaining lifetime. The majority of patients who died had explicitly adverse pre-existing factors and rarely completed RT as scheduled. Latency to RT and RT duration occupied more than half of the remaining lifetime. (orig.) [de

  6. The Prognostic Roles of Gender and O6-Methylguanine-DNA Methyltransferase Methylation Status in Glioblastoma Patients: The Female Power.

    Science.gov (United States)

    Franceschi, Enrico; Tosoni, Alicia; Minichillo, Santino; Depenni, Roberta; Paccapelo, Alexandro; Bartolini, Stefania; Michiara, Maria; Pavesi, Giacomo; Urbini, Benedetta; Crisi, Girolamo; Cavallo, Michele A; Tosatto, Luigino; Dazzi, Claudio; Biasini, Claudia; Pasini, Giuseppe; Balestrini, Damiano; Zanelli, Francesca; Ramponi, Vania; Fioravanti, Antonio; Giombelli, Ermanno; De Biase, Dario; Baruzzi, Agostino; Brandes, Alba A

    2018-04-01

    Clinical and molecular factors are essential to define the prognosis in patients with glioblastoma (GBM). O6-methylguanine-DNA methyltransferase (MGMT) methylation status, age, Karnofsky Performance Status (KPS), and extent of surgical resection are the most relevant prognostic factors. Our investigation of the role of gender in predicting prognosis shows a slight survival advantage for female patients. We performed a prospective evaluation of the Project of Emilia Romagna on Neuro-Oncology (PERNO) registry to identify prognostic factors in patients with GBM who received standard treatment. A total of 169 patients (99 males [58.6%] and 70 females [41.4%]) were evaluated prospectively. MGMT methylation was evaluable in 140 patients. Among the male patients, 36 were MGMT methylated (25.7%) and 47 were unmethylated (33.6%); among the female patients, 32 were methylated (22.9%) and 25 were unmethylated (17.9%). Survival was longer in the methylated females compared with the methylated males (P = 0.028) but was not significantly different between the unmethylated females and the unmethylated males (P = 0.395). In multivariate analysis, gender and MGMT methylation status considered together (methylated females vs. methylated males; hazard ratio [HR], 0.459; 95% confidence interval [CI], 0.242-0.827; P = 0.017), age (HR, 1.025; 95% CI, 1.002-1.049; P = 0.032), and KPS (HR, 0.965; 95% CI, 0.948-0.982; P factor. Copyright © 2018 Elsevier Inc. All rights reserved.

  7. Effects of chestnut tannins on performance and antioxidative status of transition dairy cows.

    Science.gov (United States)

    Liu, H W; Zhou, D W; Li, K

    2013-09-01

    This study was conducted to evaluate the effects of chestnut tannins (CT) on performance and antioxidative status of transition dairy cows. Twenty multiparous Chinese Holstein cows in late gestation were paired according to expected calving date and randomly assigned either to a diet supplemented with CT (CNT, 10 g of CT/kg of diet, dry matter basis) or to an unsupplemented control (CON) diet from 3 wk prepartum to 3 wk postpartum. Blood samples were taken on d -21, 1, 7, and 21 relative to calving for analysis of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), total antioxidant capacity (T-AOC), and malondialdehyde (MDA). Liver samples were taken by puncture biopsy on d 1 and 21 relative to calving for analysis of SOD, GSH-Px, and MDA. Data were analyzed for a completely randomized block design with repeated measures. The addition of CT had no significant effects on dry matter intake, body weight, body condition score, milk yield, 3.5% fat-corrected milk yield, and milk composition but did decrease milk MDA and somatic cell score in transition dairy cows. Dry matter intake decreased from d -21 to 0 and increased from d 1 to 21 relative to calving across treatments. During the experimental period, body weight and body condition score decreased, whereas milk MDA and somatic cell score increased across treatments. A time effect was also observed for plasma MDA, which peaked on d 1 relative to calving and remained higher than that on d -21 relative to calving across treatments. Addition of CT decreased MDA concentrations in plasma and liver. Neither time nor CT × time effects were observed for SOD and T-AOC in plasma and SOD and GSH-Px in liver; a time effect was observed for plasma GSH-Px, which peaked on d 1 relative to calving and remained higher than those on d -21 relative to calving across treatments. Addition of CT increased SOD, GSH-Px, and T-AOC activities in plasma and SOD and GSH-Px activities in liver. In conclusion, addition of CT might

  8. Survival of patients with head and neck cancer. Impact of physical status and comorbidities

    Energy Technology Data Exchange (ETDEWEB)

    Sadat, F. [Friedrich Alexander Univ., Erlangen (Germany). Clinic of Radiotherapy; Wienke, A. [Martin Luther Univ. Halle-Wittenberg, Halle/Saale (Germany). Inst. of Medical Epidemiology; Dunst, J. [Schleswig-Holstein Univ., Luebeck (Germany). Clinic of Radiotherapy; Kuhnt, T. [Rostock Univ. (Germany). Dept. of Radiation Oncology

    2012-01-15

    Prognostic factors (e.g., gender, tumor stage, and hypoxia) have an impact on survival in patients with head and neck cancer. Thus, the impact of physical status and comorbidities on treatment decision and survival were evaluated. Patients and methods A total of 169 primary, inoperable patients with squamous cell cancer of the head and neck were retrospectively investigated. Patients were treated with hyperfractionated accelerated radio(chemo)therapy (HARcT) or hypofractionated radio(chemo)therapy (HypoRcT). Depending on the individual patient's situation (Karnofsky Performance Index, KPI), treatment for patients with a KPI of 80-100% was generally radiochemotherapy and for patients with a KPI {<=} 70% treatment was radiotherapy alone. In addition, all comorbidities were evaluated. Uni- and multivariate proportional hazards model were used, and overall survival (OS) was estimated by the Kaplan-Meier method. Results Treatment consisted of HARcT for 76 patients (45%), HART for 28 patients (17%), HypoRcT for 14 patients(8%), and HypoRT for 51 patients (30%). Of the patients, 107 patients (63%) presented with a KPI of 80-100%. OS (20%) was significantly better for patients with a KPI of 80-100%, while the OS for patients with a KPI {<=} 70% was 8% (p < 0.001). Good KPI, total irradiation dose (> 70 Gy), and chemotherapy were significant prognostic factors for better OS. Conclusion Our retrospective analysis shows that performance status with dependency on comorbidities was an independent risk factor for OS. (orig.)

  9. Survival of patients with head and neck cancer. Impact of physical status and comorbidities

    International Nuclear Information System (INIS)

    Sadat, F.; Wienke, A.; Dunst, J.; Kuhnt, T.

    2012-01-01

    Prognostic factors (e.g., gender, tumor stage, and hypoxia) have an impact on survival in patients with head and neck cancer. Thus, the impact of physical status and comorbidities on treatment decision and survival were evaluated. Patients and methods A total of 169 primary, inoperable patients with squamous cell cancer of the head and neck were retrospectively investigated. Patients were treated with hyperfractionated accelerated radio(chemo)therapy (HARcT) or hypofractionated radio(chemo)therapy (HypoRcT). Depending on the individual patient's situation (Karnofsky Performance Index, KPI), treatment for patients with a KPI of 80-100% was generally radiochemotherapy and for patients with a KPI ≤ 70% treatment was radiotherapy alone. In addition, all comorbidities were evaluated. Uni- and multivariate proportional hazards model were used, and overall survival (OS) was estimated by the Kaplan-Meier method. Results Treatment consisted of HARcT for 76 patients (45%), HART for 28 patients (17%), HypoRcT for 14 patients(8%), and HypoRT for 51 patients (30%). Of the patients, 107 patients (63%) presented with a KPI of 80-100%. OS (20%) was significantly better for patients with a KPI of 80-100%, while the OS for patients with a KPI ≤ 70% was 8% (p 70 Gy), and chemotherapy were significant prognostic factors for better OS. Conclusion Our retrospective analysis shows that performance status with dependency on comorbidities was an independent risk factor for OS. (orig.)

  10. Patients who die during palliative radiotherapy. Status survey

    Energy Technology Data Exchange (ETDEWEB)

    Berger, B.; Ankele, H.; Bamberg, M.; Zips, D. [University of Tuebingen, Department of Radiation Oncology, Tuebingen (Germany)

    2014-02-15

    Palliative radiotherapy (RT) is routinely used in end of life care of patients with advanced malignancies; however, unnecessarily burdensome treatment shortly before death should be avoided. There is little knowledge on incidence and causes of intercurrent deaths during palliative RT. In this study death events among inpatients receiving palliative RT between January 2009 and December 2011 at this department were retrospectively analyzed. Among epidemiological factors, treatment schedule and chronology, latency and duration of treatment in relation to the actual survival were identified. In this study 52 patients died during or shortly after palliative RT. Symptomatic bone metastases and brain metastases represented the most common RT indications. The general health status was poor with a median Karnofsky performance score of 50 %, RT was realized with a median single dose of 2.5 Gy to a median total dose of 30.5 Gy and was stopped prematurely in 73 % of patients. On average 53 % of the remaining lifetime was occupied by latency to starting RT. Once RT was begun the treatment duration required a median 64 % of the still remaining lifetime. The majority of patients who died had explicitly adverse pre-existing factors and rarely completed RT as scheduled. Latency to RT and RT duration occupied more than half of the remaining lifetime. (orig.) [German] Die palliative Radiotherapie (RT) hat einen hohen Stellenwert in der Symptomenkontrolle terminal erkrankter Tumorpatienten. Unnoetig belastende Therapien kurz vor Lebensende sollten jedoch vermieden werden. Bislang gibt es kaum strukturierte Daten ueber Sterbefaelle unter palliativer RT. Im Rahmen der vorgestellten Studie wurden die Sterbefaelle unter stationaer palliativ bestrahlten Patienten der eigenen Abteilung zwischen Januar 2009 und Dezember 2011 analysiert. Ausgewertet wurden epidemiologische Faktoren, Behandlungskonzept und -verlauf. Zeit bis zum RT-Beginn und RT-Dauer wurden ins Verhaeltnis zur tatsaechlichen

  11. Low vitamin D status is associated with reduced muscle mass and impaired physical performance in frail elderly people

    NARCIS (Netherlands)

    Tieland, C.A.B.; Brouwer, E.M.; Nienaber-Rousseau, C.; Loon, van L.J.C.; Groot, de C.P.G.M.

    2013-01-01

    Background/Objectives: Serum 25-hydroxyvitamin D (25(OH)D) status has been associated with muscle mass, strength and physical performance in healthy elderly people. Yet, in pre-frail and frail elderly people this association has not been studied. The objective of this study was to explore the

  12. The impact of physical performance and cognitive status on subsequent ADL disability in low-functioning older adults

    NARCIS (Netherlands)

    Kempen, GIJM; Ormel, J

    Objectives. The purpose of this study was to examine the independent contributions of physical performance and cognitive status to subsequent levels of ADL disability in low-functioning non-institutionalized older adults. Methods. A prospective cohort study included 416 women and 141 men 57 years of

  13. Clinical performance of two visual scoring systems in detecting and assessing activity status of occlusal caries in primary teeth

    DEFF Research Database (Denmark)

    Braga, M M; Ekstrand, K R; Martignon, S

    2010-01-01

    This study aimed to compare the clinical performance of two sets of visual scoring criteria for detecting caries severity and assessing caries activity status in occlusal surfaces. Two visual scoring systems--the Nyvad criteria (NY) and the ICDAS-II including an adjunct system for lesion activity...

  14. Performed and perceived walking ability in relation to the Expanded Disability Status Scale in persons with multiple sclerosis

    DEFF Research Database (Denmark)

    Langeskov-Christensen, D; Feys, P; Baert, I

    2017-01-01

    BACKGROUND: The severity of walking impairment in persons with multiple sclerosis (pwMS) at different levels on the expanded disability status scale (EDSS) is unclear. Furthermore, it is unclear if the EDSS is differently related to performed- and perceived walking capacity tests. AIMS: To quantify...

  15. Factoring socioeconomic status into cardiac performance profiling for hospitals: does it matter?

    Science.gov (United States)

    Alter, David A; Austin, Peter C; Naylor, C David; Tu, Jack V

    2002-01-01

    Critics of "scorecard medicine" often highlight the incompleteness of risk-adjustment methods used when accounting for baseline patient differences. Although socioeconomic status is a highly important determinant of adverse outcome for patients admitted to the hospital with acute myocardial infarction, it has not been used in most risk-adjustment models for cardiovascular report cards. To determine the incremental impact of socioeconomic status adjustments on age, sex, and illness severity for hospital-specific 30-day mortality rates after acute myocardial infarction. The authors compared the absolute and relative hospital-specific 30-day acute myocardial infarction mortality rates in 169 hospitals throughout Ontario between April 1, 1994 and March 31, 1997. Patient socioeconomic status was characterized by median neighborhood income using postal codes and 1996 Canadian census data. They examined two risk-adjustment models: the first adjusted for age, sex, and illness severity (standard), whereas the second adjusted for age, sex, illness severity, and median neighborhood income level (socioeconomic status). There was an extremely strong correlation between 'standard' and 'socioeconomic status' risk-adjusted mortality rates (r = 0.99). Absolute differences in 30-day risk-adjusted mortality rates between the socioeconomic status and standard risk-adjustment models were small (median, 0.1%; 25th-75th percentile, 0.1-0.2). The agreement in the quintile rankings of hospitals between the socioeconomic status and standard risk-adjustment models was high (weighted kappa = 0.93). Despite its importance as a determinant of patient outcomes, the effect of socioeconomic status on hospital-specific mortality rates over and above standard risk-adjustment methods for acute myocardial infarction hospital profiling in Ontario was negligible.

  16. Performance of Comorbidity, Risk Adjustment, and Functional Status Measures in Expenditure Prediction for Patients With Diabetes

    OpenAIRE

    Maciejewski, Matthew L.; Liu, Chuan-Fen; Fihn, Stephan D.

    2009-01-01

    OBJECTIVE?To compare the ability of generic comorbidity and risk adjustment measures, a diabetes-specific measure, and a self-reported functional status measure to explain variation in health care expenditures for individuals with diabetes. RESEARCH DESIGN AND METHODS?This study included a retrospective cohort of 3,092 diabetic veterans participating in a multisite trial. Two comorbidity measures, four risk adjusters, a functional status measure, a diabetes complication count, and baseline ex...

  17. Upper urinary tract stone disease in patients with poor performance status: active stone removal or conservative management?

    Science.gov (United States)

    Yamashita, Shimpei; Kohjimoto, Yasuo; Hirabayashi, Yasuo; Iguchi, Takashi; Iba, Akinori; Higuchi, Masatoshi; Koike, Hiroyuki; Wakamiya, Takahito; Nishizawa, Satoshi; Hara, Isao

    2017-11-16

    It remains controversial as to whether active stone removal should be performed in patients with poor performance status because of their short life expectancy and perioperative risks. Our objectives were to evaluate treatment outcomes of active stone removal in patients with poor performance status and to compare life prognosis with those managed conservatively. We retrospectively reviewed 74 patients with Eastern Cooperative Oncology Group performance status 3 or 4 treated for upper urinary tract calculi at our four hospitals between January 2009 and March 2016. Patients were classified into either surgical treatment group or conservative management group based on the presence of active stone removal. Stone-free rate and perioperative complications in surgical treatment group were reviewed. In addition, we compared overall survival and stone-specific survival between the two groups. Cox proportional hazards analysis was performed to investigate predictors of overall survival and stone-specific survival. Fifty-two patients (70.3%) underwent active stone removal (surgical treatment group) by extracorporeal shock wave lithotripsy (n = 6), ureteroscopy (n = 39), percutaneous nephrolithotomy (n = 6) or nephrectomy (n = 1). The overall stone-free rate was 78.8% and perioperative complication was observed in nine patients (17.3%). Conservative treatment was undergone by 22 patients (29.7%) (conservative management group). Two-year overall survival rates in surgical treatment and conservative management groups were 88.0% and 38.4%, respectively (p performance status could be performed safely and effectively. Compared to conservative management, surgical stone treatment achieved longer overall survival and stone-specific survival.

  18. 198Au grain implantation for early tongue cancer in patients of advanced age or poor performance status

    International Nuclear Information System (INIS)

    Ryu, Yoshiharu; Shibuya, Hitoshi; Hayashi, Keiji

    2013-01-01

    Brachytherapy using 198 Au grains is minimally invasive and the only curative treatment for early tongue cancer in patients of advanced age or poor performance status available in our institution. From March 1993 to February 2008, 198 Au grains were used to treat a group of 96 Stage I–II tongue cancer patients who could not undergo surgery or brachytherapy using 192 Ir pins because of an advanced age (≥75 years) or poor performance status (≥2). The patients were followed for 3.9 ± 3.3 years, and the cause-specific survival and local control rates were determined. Survival analyses were performed using the Kaplan-Meier method, and univariate and multivariate analyses were performed using the Cox proportional hazard model. The results were compared with those for a group of 193 early tongue-cancer patients who underwent treatment using iridium pins. The 5-year cause-specific survival and local control rates of the 198 Au grains group were 71% and 68%, respectively, both of which were 16% lower than the corresponding rates for the 192 Ir pins group. Our study demonstrated that as the last curative treatment available, 198 Au grain implantation could be used to achieve moderate treatment results for early tongue cancer in patients of advanced age or poor performance status

  19. The effect of pre-exercise ingestion of corinthian currant on endurance performance and blood redox status.

    Science.gov (United States)

    Deli, Chariklia K; Poulios, Athanasios; Georgakouli, Kalliopi; Papanikolaou, Konstantinos; Papoutsis, Alexandros; Selemekou, Maria; Karathanos, Vaios T; Draganidis, Dimitris; Tsiokanos, Athanasios; Koutedakis, Yiannis; Fatouros, Ioannis G; Jamurtas, Athanasios Z

    2018-02-22

    The present study investigated the effect of Corinthian currant pre-exercise supplementation on metabolism, performance and blood redox status during, and after prolonged exercise. Eleven healthy participants (21-45y) performed a 90-min constant-intensity (60-70% VO 2max ) submaximal-trial, plus a time-trial (TT) to exhaustion (95% VO 2max ) after consuming an isocaloric (1.5g CHO/kg BM) amount of randomly assigned Corinthian currant or glucose-drink, or water (control). Blood was drawn at baseline, pre-exercise, 30min, 60min, 90min of submaximal-trial, post-TT, and 1h post-TT. Post-ingestion blood glucose (GLU) under Corinthian currant was higher compared with water, and similar compared with glucose-drink throughout the study. Respiratory quotient under Corinthian currant was similar with glucose-drink and higher than water throughout the submaximal trial. Accordingly, higher CHO and lower fat oxidation were observed under Corinthian currant compared with water. The TT performance was similar between Corinthian currant, glucose-drink and water. Redox status were similar under all three conditions. Reduced glutathione (GSH) declined while total antioxidant capacity (TAC) and uric acid increased during exercise. GSH and TAC returned to baseline, while uric acid remained increased the following 1h. Corinthian currant, although did not alter exercise-mediated redox status changes and performance, was equally effective to a glucose-drink in maintaining GLU levels during prolonged cycling.

  20. Application status and performance analysis of robot in nuclear power plants

    International Nuclear Information System (INIS)

    Liu Chengze; Yan Zhi; Deng Jingshan

    2012-01-01

    Application status of robot in nuclear power plants in some countries is summarized. The related robots include accident response robot, dismantling and cleaning robot, in-service inspection robot, special-purpose robot and so on. Finally, some key technologies such as the radiation-tolerance and reliability of the robot systems are analyzed in details. (authors)

  1. The association of self-reported sleep, weight status, and academic performance in fifth-grade students.

    Science.gov (United States)

    Stroebele, Nanette; McNally, Janise; Plog, Amy; Siegfried, Scott; Hill, James O

    2013-02-01

    To improve support and justification for health promotion efforts in schools, it is helpful to understand how students' health behaviors affect academic performance. Fifth-grade students completed an online school-administered health survey with questions regarding their eating behavior, physical activity, academic performance, and sleep patterns. Differences in health behaviors were examined by sex, self-reported weight status, and sufficient (≥9 hours) versus insufficient sleep. Logistic regression was used to determine the relationship between academic performance and the health behaviors. One third of the sample did not get the recommended amount of physical activity and more than half of the students watched television ≥ 2 hours/day. Self-reported overweight status was related to lower self-reported academic performance, fewer lunch and breakfast occasions, less physical activity, not meeting the recommendations for vegetable and soda consumption as well as hours of television watching. Sufficient sleep (≥9 hours/night) was associated with better grades, meeting the recommended hours of daily television watching and video game playing, being more physically active and increased breakfast and lunch frequency. Percentage of serving free/reduced lunch, soda consumption, breakfast frequency, amount of physical activity, and television watching were associated with academic performance. More positive health behaviors generally were associated with better academic performance. Promoting healthy behaviors in schools might improve not only students' health academic performance as well. © 2013, American School Health Association.

  2. Update of super-speed ground transportation technology development status and performance capabilities. CIGGT report No. 89-16

    Energy Technology Data Exchange (ETDEWEB)

    Hayes, W F

    1990-01-01

    This report presents an update of the Phase II assessment of development status and performance capabilities for four candidate super-speed ground transportation system alternatives for the Las Vegas-Southern California corridor. The four alternatives considered are the TGV wheel-on-rail technology, the Transrapid TR- 07 long-stator Electromagnetic Maglev (EMS) technology, the Japan Railways MLU Electrodynamic Maglev (EDS) technology, and the HSST Corp. HSST-400 short-stator Electromagnetic Maglev technology.

  3. Effect of Cocoa Butter and Sunflower Oil Supplementation on Performance, Immunoglobulin, and Antioxidant Vitamin Status of Rats

    OpenAIRE

    Ebru Yıldırım; Miyase Çınar; İlkay Yalçınkaya; Hüsamettin Ekici; Nurgül Atmaca; Enes Güncüm

    2014-01-01

    This study investigated the effects of cocoa butter and sunflower oil alone and in combination on performance, some biochemical parameters, immunoglobulin, and antioxidant vitamin status in Wistar rats. Forty-eight male rats were assigned to four groups, consisting of 12 rats with 3 replicates. Control received balanced rat diet without oil, cocoa butter group received 3.5% cocoa butter, sunflower oil group received 3.5% sunflower oil, the last group received 1.75% sunflower oil + 1.75% cocoa...

  4. The Quadratic Relationship between Socioeconomic Status and Learning Performance in China by Multilevel Analysis: Implications for Policies to Foster Education Equity

    Science.gov (United States)

    Zhao, Ningning; Valcke, Martin; Desoete, Annemie; Verhaeghe, JeanPierre

    2012-01-01

    The purpose of the present study is to explore the relationship between family socioeconomic status and mathematics performance on the base of a multi-level analysis involving a large sample of Chinese primary school students. A weak relationship is found between socioeconomic status and performance in the Chinese context. The relationship does…

  5. Status of compost usage and its performance on vegetable production in Monga areas of Bangladesh

    OpenAIRE

    G.K.M.M. Rahman

    2014-01-01

    The present study was carried out to assess the existing status of compost usage on vegetable production and determine the overall effect of household waste compost (HWC) on growth and yield of vegetables and enhancement of soil fertility in the monga areas of Bangladesh. A field survey was conducted on 152 sampled farmers during 2010 to 2011. Questionnaire containing both closed and open-ended questions were used to assess existing production practices of vegetables using compost in both hom...

  6. Prediction of 90 Day and Overall Survival after Chemoradiotherapy for Lung Cancer: Role of Performance Status and Body Composition.

    Science.gov (United States)

    Bowden, J C S; Williams, L J; Simms, A; Price, A; Campbell, S; Fallon, M T; Fearon, K C H

    2017-09-01

    If appropriate patients are to be selected for lung cancer treatment, an understanding of who is most at risk of adverse outcomes after treatment is needed. The aim of the present study was to identify predictive factors for 30 and 90 day mortality after chemoradiotherapy (CRT), and factors that were prognostic for overall survival. A retrospective cohort study of 194 patients with lung cancer who had undergone CRT in South East Scotland from 2008 to 2010 was undertaken. Gender, age, cancer characteristics, weight loss, body mass index (BMI), performance status (Eastern Cooperative Oncology Group; ECOG) and computed tomography-derived body composition variables were examined for prognostic significance using Cox's proportional hazards model and logistic regression. The median overall survival was 19 months (95% confidence interval 16.3, 21.7). Four of 194 patients died within 30 days of treatment completion, for which there were no independent predictive variables; 22/194 (11%) died within 90 days of treatment completion. BMI < 20 and ECOG performance status ≥2 were independent predictors of death within 90 days of treatment completion (P = 0.001 and P = 0.004, respectively). Patients with either BMI < 20 or ECOG performance status ≥ 2 had an odds ratio of death within 90 days of 5.97 (95% confidence interval 2.20, 16.19), rising to an odds ratio of 13.27 (1.70, 103.47) for patients with both BMI < 20 and ECOG performance status ≥ 2. Patients with low muscle attenuation had significantly reduced overall survival (P = 0.004); individuals with low muscle attenuation had a median survival of 15.2 months (95% confidence interval 12.7, 17.7) compared with 23.0 months (95% confidence interval 18.3, 27.8) for those with high muscle attenuation, equating to a hazard ratio of death of 1.62 (95% confidence interval 1.17, 2.23, P = 0.003). Poor performance status, low BMI and low muscle attenuation identify patients at increased risk of premature death after

  7. Effects of polymannuronate on performance, antioxidant capacity, immune status, cecal microflora, and volatile fatty acids in broiler chickens.

    Science.gov (United States)

    Zhu, Wenhui; Li, Defa; Wang, Jianhong; Wu, Hui; Xia, Xuan; Bi, Wanghua; Guan, Huashi; Zhang, Liying

    2015-03-01

    The aim of this study was to assess the effects of purified polymannuronate (PM) obtained from marine brown algae on the performance, antioxidant capacity, immune status, and cecal fermentation profile of broiler chickens. In a 42 d experiment, 540 (average BW 43.77±1.29 g) 1-d-old Arbor Acres male broilers were randomly divided into 5 treatments with 6 replicates of 18 chicks and fed a corn and soybean meal (SBM)-based diet supplemented with 0, 1, 2, 3, or 4 g/kg polymannuronate. Adding polymannuronate to the broiler chickens' diets resulted in a significantly increased ADG and improved feed conversion compared with the control treatment. From d 1 to 42, the ADG of broilers fed 1, 2, 3, or 4 g/kg of polymannuronate was increased by 2.58, 4.33, 4.20, and 3.47%, respectively. Furthermore, parameters related to immune status, antioxidant capacity, and composition of the cecal microflora in broiler chickens fed the polymannuronate-containing diets were altered compared with broiler chickens fed a diet without polymannuronate. Supplementation with polymannuronate significantly increased the concentrations of lactic acid and acetic acid in the cecum compared with the control group. The results indicate that polymannuronate has the potential to improve broiler chicken immune status, antioxidant capacity, and performance. © 2015 Poultry Science Association Inc.

  8. Use of radioimmunoassay techniques to study the effects of nutritional status and breed on reproductive performance of goats

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez, N; Carmenate, C; Pedroso, R; Perez, L O; Alvarez, T R; Gonzalez, N; Felipe, N; Bravo, M [Centro de Investigaciones para el Mejoramiento Animal, Havana (Cuba)

    1996-05-01

    Goats from 2-5 years old in 15 herds of four breeds, (Saanen, Nubian, Toggenburg and Alpine), were used in three experiments to determine reproductive behaviour (Experiment 1), metabolic profile (Experiment 2) and fertility of induced and synchronized oestrus (Experiment 3). Season, breed and physiological status were significant factors affecting reproductive behaviour and metabolic status (P<0.05). The principal causes of infertility in induced oestrus were failures in conception, early embryonic mortality and anovulatory oestrus. The herds had long intervals from birth to first insemination (306-458 days) and to first pregnancy (471-511 days), and low fertility (14-31%). The breeding patter was similar to breeds in temperate zones. Energy and mineral imbalances were found. Further research is necessary to improve reproductive performance of these breeds under tropical conditions. (author). 25 refs, 3 figs, 4 tabs.

  9. Beyond adoption status: Post-adoptive parental involvement and children's reading and math performance from kindergarten to first grade.

    Science.gov (United States)

    Tan, Tony Xing; Kim, Eun Sook; Baggerly, Jennifer; Mahoney, E Emily; Rice, Jessica

    2017-01-01

    In this study, we went beyond adoption status to examine the associations between postadoption parental involvement and children's reading and math performance from kindergarten to first grade. Secondary data on a sample of adopted children and nonadopted children were drawn from the Early Childhood Longitudinal Study-Kindergarten Class of 1998 to 1999 (ECLS-K). Weighted data on the children's reading performance were available for 13,900 children (181 were adopted); weighted data on the children's math performance were available for 14,128 children (184 were adopted). Descriptive data showed no group difference in reading scores at all 3 Waves but adopted children scored lower than nonadopted children in math at Wave 2 (Spring of kindergarten) and Wave 3 (Spring of first grade). However, controlling for 6 covariates, latent growth modeling showed that adoption status was unrelated to Wave 1 reading and math scores or subsequent growth rate. Rather, parents' beliefs on skills needed to succeed in kindergarten were a significant predictor of reading and math performance at Wave 1 and subsequent growth rates, and parents' educational expectation was a significant predictor of growth rate in reading and math. Our findings highlight the importance of parental involvement in adopted children's learning. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  10. Correlation between nutritional status and comprehensive physical performance measures among older adults with undernourishment in residential institutions

    Directory of Open Access Journals (Sweden)

    Singh DKA

    2014-08-01

    Full Text Available Devinder KA Singh,1 Zahara A Manaf,2 Noor Aini M Yusoff,3 Nur A Muhammad,2 Mei Fang Phan,1 Suzana Shahar2 1Physiotherapy Program, School of Rehabilitation Sciences, 2Nutrition and Dietetics Program, School of Health Care Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, 3ASIA Metropolitan University, Cheras, Malaysia Purpose: The consequences of combined undernourishment and decreased physical ­performance in older adults are debilitating and increases cost of care. To date, the information regarding the association between nutritional status and physical performance does not provide a complete picture. Most studies used limited or self-reported measures to evaluate physical performance. The objective of this study was to examine the correlation between nutritional status and comprehensive physical performance measures among undernourished older adults who reside in residential institutions.Methods: Forty-seven older adults (26 males, 21 females aged ≥60 (69.23±8.63 years who were identified as undernourished from two residential institutions participated in this study. A battery of physical performance tests (10 m gait speed test, dominant hand grip strength test, timed five-repetition sit-to-stand test, ten step test, arm curl test, scratch test, and respiratory muscle strength test, biochemical profiles (serum albumin, hemoglobin, serum ferritin, and prealbumin levels, and falls risk using the short-form Physiological Profile Approach were performed. The Functional Ability Questionnaire and Geriatric Depression Scale were also administered.Results: The results demonstrated that generally older adults with undernourishment scored poorly on the physical performance tests, had depression, and a high risk of falls. Biochemical results demonstrated that 10.9% of the participants were anemic, 63% had hypoalbuminemia (<3.5 g/dL, and 21.7% were at risk of protein energy malnutrition with prealbumin level (100–170 mg/L. A significant

  11. THE EFFECTS OF INCOME, GENDER, AGE, EDUCATION, WORKING PERIOD, INSURANCE, TRAINING, AND WORKER STATUS ON OUTSOURCED AND WORKERS PERFORMANCE IN SOUTH SUMATERA IN MANUFACTURING COMPANIES

    OpenAIRE

    Ratna Juwita; Nurlina Tarmizi; Didik Susetyo; Bambang Bemby Soebyakto

    2017-01-01

    This research investigated the effects of income, gender, age, education, working period, insurance, training and workers’ status (outsourcing or permanent) on performance. The result showed that gender, education, insurance, training and status had positive and significant effect on performace. Income had significant and negative effect on performance, the increased income would decrease performance. Age had positive but not significant effect, the increased age would decrease...

  12. The Mirror Fusion Test Facility cryogenic system: Performance, management approach, and present equipment status

    International Nuclear Information System (INIS)

    Slack, D.S.; Chronis, W.C.

    1987-01-01

    The cryogenic system for the Mirror Fusion Test Facility (MFTF) is a 14-kW, 4.35-K helium refrigeration system that proved to be highly successful and cost-effective. All operating objectives were met, while remaining within a few percent of initial cost and schedule plans. The management approach used in MFTF allowed decisions to be made quickly and effectively, and it helped keep costs down. Manpower levels, extent and type of industrial participation, key aspects of subcontractor specifications, and subcontractor interactions are reviewed, as well as highlights of the system tests, operation, and present equipment status. Organizations planning large, high-technology systems may benefit from this experience with the MFTF cryogenic system

  13. Kalpakkam multigroup cross section set for fast reactor applications - status and performance

    International Nuclear Information System (INIS)

    Ramanadhan, M.M.; Gopalakrishnan, M.M.

    1986-01-01

    This report documents the status of the presently created set of multigroup constants at Kalpakkam. The list of nuclides processed and the details of multigroup structure are given. Also included are the particulars of dilutions and temperatures for each nuclide in the multigroup cross section set for which self shielding factors have been calculated. Using this new multigroup cross section set, measured integral quantities such as K-eff, central reaction rate ratios, central reactivity worths etc. were calculated for a few fast critical benchmark assemblies and the calculated values of neutronic parameters obtained were compared with those obtained using the available Cadarache cross section library and those published in literature for ENDF/B-IV based set and Japanese evaluated nuclear data library (JENDL). The details of analyses are documented along with the conclusions. (author). 17 refs., 12 tabs

  14. Performance Status and Change--Measuring Education System Effectiveness with Data from PISA 2000-2009

    Science.gov (United States)

    Lenkeit, Jenny; Caro, Daniel H.

    2014-01-01

    Reports of international large-scale assessments tend to evaluate and compare education system performance based on absolute scores. And policymakers refer to high-performing and economically prosperous education systems to enhance their own systemic features. But socioeconomic differences between systems compromise the plausibility of those…

  15. Current Status and Performance Tests of Korea Heat Load Test Facility KoHLT-EB

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sukkwon; Jin, Hyunggon; Shin, Kyuin; Choi, Boguen; Lee, Eohwak; Yoon, Jaesung; Lee, Dongwon [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Kim, Duckhoi; Cho, Seungyon [National Fusion Research Institute, Daejeon (Korea, Republic of)

    2013-05-15

    A commissioning test has been scheduled to establish the installation and preliminary performance experiments of the copper hypervapotron mockups. And a qualification test will be performed to evaluate the CuCrZr duct liner in the ITER neutral beam injection facility and the ITER first wall small-scale mockups of the semi-prototype, at up to 1.5 and 5 MW/m{sup 2} high heat flux. Also, this system will be used to test other PFCs for ITER and materials for tokamak reactors. Korean high heat flux test facility(KoHLT-EB; Korea Heat Load Test facility - Electron Beam) by using an electron beam system has been constructed in KAERI to perform the qualification test for ITER blanket FW semi-prototype mockups, hypervapotron cooling devices in fusion devices, and other ITER plasma facing components. The commissioning and performance tests with the supplier of e-gun system have been performed on November 2012. The high heat flux test for hypervapotron cooling device and calorimetry were performed to measure the surface heat flux, the temperature profile and cooling performance. Korean high heat flux test facility for the plasma facing components of nuclear fusion machines will be constructed to evaluate the performance of each component. This facility for the plasma facing materials will be equipped with an electron beam system with a 60 kV acceleration gun.

  16. Cognitive performance and iron status are negatively associated with hookworm infection in Cambodian schoolchildren

    DEFF Research Database (Denmark)

    Khov, Kuong; Fiorentino, Marion; Perignon, Marlene

    2016-01-01

    Soil-transmitted helminth (STH) infection has been associated with lower cognitive performance of schoolchildren. To identify pathways through which STH infection might affect school performance, baseline data from a large rice-fortification trial in Cambodian schoolchildren were used to investig...

  17. Effect of citric acid, avilamycin, and their combination on the performance, tibia ash, and immune status of broilers.

    Science.gov (United States)

    Chowdhury, R; Islam, K M S; Khan, M J; Karim, M R; Haque, M N; Khatun, M; Pesti, G M

    2009-08-01

    The aim of this study was to determine the effect of the supplementation of an organic acid (citric acid), antibiotic growth promoter (avilamycin), and their combination for a period of 35 d on the growth, feed efficiency, carcass yield, tibia ash, and immune status of broilers. One hundred sixty 1-d-old broiler chicks (Hubbard Classic) were randomly distributed into 4 groups with 4 replicate cages having 10 birds in each. A corn-soybean-based diet was used as the basal diet (control). The basal diet was supplemented with an organic acid (citric acid, 0.5%), an antibiotic growth promoter (avilamycin, 0.001%), and their combination in other groups. The highest BW was attained in citric acid-fed chicks (1,318 g), which was significantly (P 0.05). Total feed intake was higher in citric acid-fed chicks compared with antibiotic-supplemented chicks. The addition of citric acid improved feed conversion efficiency (g of weight gain/ kg of feed intake) significantly (P ash percentage significantly (P ash, and immune status of broilers. Therefore, citric acid might be a useful additive instead of antibiotic growth promoters such as avilamycin, considering performance and health status of broilers.

  18. Oral health status and academic performance among Ohio third-graders, 2009-2010.

    Science.gov (United States)

    Detty, Amber M R; Oza-Frank, Reena

    2014-01-01

    Although recent literature indicated an association between dental caries and poor academic performance, previous work relied on self-reported measures. This analysis sought to determine the association between academic performance and untreated dental caries (tooth decay) using objective measures, controlling for school-level characteristics. School-level untreated caries prevalence was estimated from a 2009-2010 oral health survey of Ohio third-graders. Prevalence estimates were combined with school-level academic performance and other school characteristics obtained from the Ohio Department of Education. Linear regression models were developed as a result of bivariate testing, and final models were stratified based upon the presence of a school-based dental sealant program (SBSP). Preliminary bivariate analysis indicated a significant relationship between untreated caries and academic performance, which was more pronounced at schools with an SBSP. After controlling for other school characteristics, the prevalence of untreated caries was found to be a significant predictor of academic performance at schools without an SBSP (P=0.001) but not at schools with an SBSP (P=0.833). The results suggest the association between untreated caries and academic performance may be affected by the presence of a school-based oral health program. Further research focused on oral health and academic performance should consider the presence and/or availability of these programs. © 2014 American Association of Public Health Dentistry.

  19. THE EFFECTS OF INCOME, GENDER, AGE, EDUCATION, WORKING PERIOD, INSURANCE, TRAINING, AND WORKER STATUS ON OUTSOURCED AND WORKERS PERFORMANCE IN SOUTH SUMATERA IN MANUFACTURING COMPANIES

    Directory of Open Access Journals (Sweden)

    Ratna Juwita

    2017-06-01

    Full Text Available This research investigated the effects of income, gender, age, education, working period, insurance, training and workers’ status (outsourcing or permanent on performance. The result showed that gender, education, insurance, training and status had positive and significant effect on performace. Income had significant and negative effect on performance, the increased income would decrease performance. Age had positive but not significant effect, the increased age would decrease performance. Working period had negative but not significsnt effect on performance, the short working period would decrease performance.

  20. Current status of the tasks performed by the Nuclear Fuel Department for the CAREM project

    International Nuclear Information System (INIS)

    Kaufmann, Federico; Perez, Lidia E.; Perez, Aaldo; Marchi, Daniel E.

    2009-01-01

    CAREM Project required to the Nuclear Fuels Department to perform the necessary tasks to define the powder characteristics and natural UO 2 -Gd 2 O 3 , UO 2 -1.8 and 3.1 % enrichment fuel pellets manufacturing and control parameters. To start with these tasks it was necessary to hire and train staff, begin the licensing process of the facilities, update infrastructure works and equipment of existing facilities. A brief description of the tasks performed is shown. (author)

  1. International experience and status of fuel element performance and modelling for water reactors

    International Nuclear Information System (INIS)

    Gittus, J.H.

    1982-04-01

    Current knowledge concerning water reactor fuel performance and technology is reviewed (212 references). The emphasis is on aspects of in-reactor performance including behaviour in accidents. Computer models for predicting fuel behaviour during the ordinary running of the reactor and during accidents are described. These codes include COMETHE, HOTROD, SLEUTH-SEER and FRAPCON. Their agreement with experimental data is examined. (U.K.)

  2. Physical performance measures that predict faller status in community-dwelling older adults.

    Science.gov (United States)

    Macrae, P G; Lacourse, M; Moldavon, R

    1992-01-01

    Falls are a leading cause of fatal and nonfatal injuries among the elderly. Accurate determination of risk factors associated with falls in older adults is necessary, not only for individual patient management, but also for the development of fall prevention programs. The purpose of this study was to evaluate the effectiveness of clinical measures, such as the one-legged stance test (OLST), sit-to-stand test (STST), manual muscle tests (MMT), and response speed in predicting faller status in community-dwelling older adults (N = 94, age 60-89 years). The variables assessed were single-leg standing (as measured by OLST), STST, and MMT of 12 different muscle groups (hip flexors, hip abductors, hip adductors, knee flexors, knee extensors, ankle dorsiflexors, ankle plantarflexors, shoulder flexors, shoulder abductors, elbow flexors, elbow extensors, and finger flexors), and speed of response (as measured by a visual hand reaction and movement time task). Of the 94 older adults assessed, 28 (29.7%) reported at least one fall within the previous year. The discriminant analysis revealed that there were six variables that significantly discriminated between fallers and nonfallers. These variables included MMT of the ankle dorsiflexors, knee flexors, hip abductors, and knee extensors, as well as time on the OLST and the STST. The results indicate that simple clinical measures of musculoskeletal function can discriminate fallers from nonfallers in community-dwelling older adults. J Orthop Sports Phys Ther 1992;16(3):123-128.

  3. Current status of the transient integral fuel element performance code URANUS

    International Nuclear Information System (INIS)

    Preusser, T.; Lassmann, K.

    1983-01-01

    To investigate the behavior of fuel pins during normal and off-normal operation, the integral fuel rod code URANUS has been extended to include a transient version. The paper describes the current status of the program system including a presentation of newly developed models for hypothetical accident investigation. The main objective of current development work is to improve the modelling of fuel and clad material behavior during fast transients. URANUS allows detailed analysis of experiments until the onset of strong material transport phenomena. Transient fission gas analysis is carried out due to the coupling with a special version of the LANGZEIT-KURZZEIT-code (KfK). Fuel restructuring and grain growth kinetics models have been improved recently to better characterize pre-experimental steady-state operation; transient models are under development. Extensive verification of the new version has been carried out by comparison with analytical solutions, experimental evidence, and code-to-code evaluation studies. URANUS, with all these improvements, has been successfully applied to difficult fast breeder fuel rod analysis including TOP, LOF, TUCOP, local coolant blockage and specific carbide fuel experiments. Objective of further studies is the description of transient PCMI. It is expected that the results of these developments will contribute significantly to the understanding of fuel element structural behavior during severe transients. (orig.)

  4. ATLAS SemiConductor Tracker and Pixel Detector: Status and Performance

    CERN Document Server

    Reeves, K; The ATLAS collaboration

    2012-01-01

    The Semi-Conductor Tracker (SCT) and the Pixel Detector are the key precision tracking devices in the Inner Detector of the ATLAS experiment at CERN LHC. The SCT is a silicon strip detector and is constructed of 4088 silicon detector modules for a total of 6.3 million strips. Each module is designed, constructed and tested to operate as a stand-alone unit, mechanically, electrically, optically and thermally. The SCT silicon micro-strip sensors are processed in the planar p-in-n technology. The signals from the strips are processed in the front-end ASICS ABCD3TA, working in the binary readout mode. The Pixel Detector consists of approximately 80 million pixels that are individually read out via chips bump-bonded to 1744 n-in-n silicon substrates. In the talk the current status of the SCT and Pixel Detector will be reviewed. We will report on the operation of the detectors including an overview of the issues we encountered and the observation of significant increases in leakage currents (as expected) from bulk ...

  5. Associations Between Balance and Muscle Strength, Power Performance in Male Youth Athletes of Different Maturity Status.

    Science.gov (United States)

    Hammami, Raouf; Chaouachi, Anis; Makhlouf, Issam; Granacher, Urs; Behm, David G

    2016-11-01

    Balance, strength and power relationships may contain important information at various maturational stages to determine training priorities. The objective was to examine maturity-specific relationships of static/dynamic balance with strength and power measures in young male athletes. Soccer players (N = 130) aged 10-16 were assessed with the Stork and Y balance (YBT) tests. Strength/power measures included back extensor muscle strength, standing long jump (SLJ), countermovement jump (CMJ), and 3-hop jump tests. Associations between balance with strength/power variables were calculated according to peak-height-velocity (PHV). There were significant medium-large sized correlations between all balance measures with back extensor strength (r = .486-.791) and large associations with power (r = .511-.827). These correlation coefficients were significantly different between pre-PHV and circa PHV as well as pre-PHV and post-PHV with larger associations in the more mature groups. Irrespective of maturity-status, SLJ was the best strength/power predictor with the highest proportion of variance (12-47%) for balance (i.e., Stork eyes opened) and the YBT was the best balance predictor with the highest proportion of variance (43-78%) for all strength/power variables. The associations between balance and muscle strength/power measures in youth athletes that increase with maturity may imply transfer effects from balance to strength/power training and vice versa in youth athletes.

  6. Image quality validation of Sentinel 2 Level-1 products: performance status at the beginning of the constellation routine phase

    Science.gov (United States)

    Francesconi, Benjamin; Neveu-VanMalle, Marion; Espesset, Aude; Alhammoud, Bahjat; Bouzinac, Catherine; Clerc, Sébastien; Gascon, Ferran

    2017-09-01

    Sentinel-2 is an Earth Observation mission developed by the European Space Agency (ESA) in the frame of the Copernicus program of the European Commission. The mission is based on a constellation of 2-satellites: Sentinel-2A launched in June 2015 and Sentinel-2B launched in March 2017. It offers an unprecedented combination of systematic global coverage of land and coastal areas, a high revisit of five days at the equator and 2 days at mid-latitudes under the same viewing conditions, high spatial resolution, and a wide field of view for multispectral observations from 13 bands in the visible, near infrared and short wave infrared range of the electromagnetic spectrum. The mission performances are routinely and closely monitored by the S2 Mission Performance Centre (MPC), including a consortium of Expert Support Laboratories (ESL). This publication focuses on the Sentinel-2 Level-1 product quality validation activities performed by the MPC. It presents an up-to-date status of the Level-1 mission performances at the beginning of the constellation routine phase. Level-1 performance validations routinely performed cover Level-1 Radiometric Validation (Equalisation Validation, Absolute Radiometry Vicarious Validation, Absolute Radiometry Cross-Mission Validation, Multi-temporal Relative Radiometry Vicarious Validation and SNR Validation), and Level-1 Geometric Validation (Geolocation Uncertainty Validation, Multi-spectral Registration Uncertainty Validation and Multi-temporal Registration Uncertainty Validation). Overall, the Sentinel-2 mission is proving very successful in terms of product quality thereby fulfilling the promises of the Copernicus program.

  7. Chronic choline supplementation improves cognitive and motor performance via modulating oxidative and neurochemical status in rats.

    Science.gov (United States)

    Tabassum, Saiqa; Haider, Saida; Ahmad, Saara; Madiha, Syeda; Parveen, Tahira

    2017-08-01

    Choline, an essential nutrient, accounts for multiple functions in the body and brain. While its beneficial effects on healthy adults are not clear, choline supplementation is important during pregnancy for brain development, in elderly patients for support of cognitive performance and in patients with neurological disorders to reduce memory deficits. Thus, the aim of this study is to investigate whether choline administration in healthy adult rats beneficially impacts cognitive and locomotor performance, and associated oxidative and neurochemical outcomes. Two groups, control and choline, received tap water and choline bitartrate, respectively at the dose equivalent to adequate intake for five weeks. Food intake and body weight were monitored daily. Behavioral analysis comprising assessment of cognitive performance (by novel object recognition, passive avoidance and Morris Water Maze test) and locomotor performance (by Open field, Kondziela's inverted screen and beam walking test) were performed. Following testing, rats were decapitated and brain samples were collected for estimation of acetylcholine, redox profile and monoamine measurements. The results showed that chronic choline administration significantly improves cognitive and locomotor performance accompanied by a reduction in oxidative stress, enhanced cholinergic neurotransmission and monoamine levels in the brain of healthy adult rats. Hence, chronic choline intake was found to improve behavioral, oxidative and neurochemical outcomes in the normal population, so it can be suggested that choline tablets can be used as a safe and effective supplement for improving the neurological health of normal individuals and that they might also be beneficial in preventing cognitive and motor disorders later in life. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. Adolescent Weight Status and Self-Reported School Performance in South Korea

    OpenAIRE

    Do, Young Kyung; Finkelstein, Eric Andrew

    2011-01-01

    Using a nationally representative sample of 142 783 middle school (13–15 years old) and high school (16–18 years old) students in South Korea, this study examined whether (1) overweight and obesity are more likely to be associated with lower self-reported school performance; (2) overweight and obese students are more likely to enrol in a vocational high school as opposed to a general high school; (3) the association between obesity and poorer self-reported school performance is mediated throu...

  9. Effect of changes in the nutritional status on the performances of growing Creole kids during an established nematode parasite infection.

    Science.gov (United States)

    Ceï, W; Archimède, H; Arquet, R; Félicité, Y; Feuillet, D; Nepos, A; Mulciba, P; Etienne, T; Alexandre, G; Bambou, J C

    2017-04-01

    In this study, we evaluated the effect of changes in the nutritional status on the performances of growing Creole kids during an established experimental gastrointestinal nematode (GIN) infection. Eighteen 6-month-old Creole kids were distributed in two main groups infected (I) and non-infected (NI) and were placed for a period of 4 weeks on each of three diets differing in their nutritional values: (1) fresh grass (FG, 6.7 MJ/kg dry matter (DM) and 7.9% crude protein (CP)) non-supplemented, (2) FG supplemented with a commercial concentrate (CC, 12.2 MJ/kg DM and 20.6% of CP), and (3) FG supplemented with dried banana (Ban, 11.1 MJ/kg DM and 4.3% CP). The experiment was designed as a split-plot with experimental infection (I and NI) as the main plot and the diets (FG, CC, and Ban) as the subplots with three replicates. We showed a significant effect of the diet changes on the fecal egg counts. A higher dry matter intake, digestibility, and growth rate were observed with the CC diet but together with a slight but significant increase of the intensity of the GIN infection. These data suggest that the improvement of the protein nutritional status during an establish GIN infection would improve the animal performance at the expense of the mechanism involved in the control of the infection.

  10. Prognostic factors in patients with malignant pleural effusion: Is it possible to predict mortality in patients with good performance status?

    Science.gov (United States)

    Abrao, Fernando Conrado; Peixoto, Renata D'Alpino; de Abreu, Igor Renato Louro Bruno; Janini, Maria Cláudia; Viana, Geisa Garcia; de Oliveira, Mariana Campello; Younes, Riad Naim

    2016-04-01

    The aim of this study was to identify predictors of mortality only in patients with malignant pleural effusion (MPE) showing good performance status which required pleural palliative procedures. All patients with MPE submitted to pleural palliative procedure were enrolled in a prospective study between 2013 and 2014. Patients with Eastern cooperative oncology group (ECOG) score zero, one, and two were considered with good performance status. The possible prognostic factors were tested for significance using the log-rank test (Kaplan-Meier method) and those with significance on univariate analysis were entered into a multivariable Cox model. A total of 64 patients were included in the analysis. Median follow-up time for surviving patients was 263 days. Median survival for the entire cohort was not reached yet. In the multivariate analysis, gastrointestinal primary site (P = 0.006), low albumin concentration in the pleural fluid (P = 0.017), and high serum NLR (P = 0.007) were associated with mortality. In our cohort of ECOG 0-2 patients with MPE submitted to pleural palliative procedures, gastrointestinal malignancy compared to other sites, low pleural fluid albumin and high NLR were significantly associated with mortality. The identification of these prognostic factors may assist the choice of the optimal palliative technique. J. Surg. Oncol. 2016;113:570-574. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  11. Outcomes in 24 selected patients with stage IVB cervical cancer and excellent performance status treated with radiotherapy and chemotherapy

    International Nuclear Information System (INIS)

    Zighelboim, Israel; Taylor, Nicholas P.; Powell, Matthew A.; Gibb, Randall K.; Rader, Janet S.; Mutch, David G.; Grigsby, Perry W.

    2006-01-01

    We sought to review outcomes in patients with stage IVB carcinoma of the cervix treated with irradiation in combination with chemotherapy. We report outcomes of 24 consecutive patients with good performance status treated from 1998 to 2005. Most of these patients underwent concurrent irradiation with platinum-based chemotherapy. Some patients received subsequent systemic chemotherapy. All patients underwent external beam radiotherapy; 7 patients (29%) had additional high-dose-rate and 12 (50%) low-dose-rate brachytherapy. Two patients (8%) received an intensity modulated radiation therapy (IMRT) boost instead of brachytherapy. The mean dose to point A was variable (73.9±19.2 Gy). Twenty patients (83%) received radio-sensitizing platinum-based chemotherapy, and the remaining had radiotherapy alone. Seven patients (29%) had further combination chemotherapy. Therapy was well tolerated. The overall survival was 44% at 36 months and 22% at 5 years. Patients with stage IVB cervical cancer have mostly been treated with palliative intent. With the advent of concurrent chemoradiation, we have treated many of these cases with aggressive combination therapy. In this series, the use of radiotherapy and multiagent chemotherapy in patients with stage IVB cervical carcinoma and good performance status was well tolerated and resulted in higher survival rates than previously reported. (author)

  12. Landsat 9 OLI 2 focal plane subsystem: design, performance, and status

    Science.gov (United States)

    Malone, Kevin J.; Schrein, Ronald J.; Bradley, M. Scott; Irwin, Ronda; Berdanier, Barry; Donley, Eric

    2017-09-01

    The Landsat 9 mission will continue the legacy of Earth remote sensing that started in 1972. The Operational Land Imager 2 (OLI 2) is one of two instruments on the Landsat 9 satellite. The OLI 2 instrument is essentially a copy of the OLI instrument flying on Landsat 8. A key element of the OLI 2 instrument is the focal plane subsystem, or FPS, which consists of the focal plane array (FPA), the focal plane electronics (FPE) box, and low-thermal conductivity cables. This paper presents design details of the OLI 2 FPS. The FPA contains 14 critically-aligned focal plane modules (FPM). Each module contains 6 visible/near-IR (VNIR) detector arrays and three short-wave infrared (SWIR) arrays. A complex multi-spectral optical filter is contained in each module. Redundant pixels for each array provide exceptional operability. Spare detector modules from OLI were recharacterized after six years of storage. Radiometric test results are presented and compared with data recorded in 2010. Thermal, optical, mechanical and structural features of the FPA will be described. Special attention is paid to the thermal design of the FPA since thermal stability is crucial to ensuring low-noise and low-drift operation of the detectors which operate at -63°C. The OLI 2 FPE provides power, timing, and control to the focal plane modules. It also digitizes the video data and formats it for the solid-state recorder. Design improvements to the FPA-FPE cables will be discussed and characterization data will be presented. The paper will conclude with the status of the flight hardware assembly and testing.

  13. Status of radionuclide sorption-desorption studies performed by the WRIT program

    International Nuclear Information System (INIS)

    Serne, R.J.; Relyea, J.F.

    1981-01-01

    This paper focuses on interactions between dissolved radionuclides in groundwater and rocks and sediments away from the nearfield repository. Two approaches were used to study the primary mechanism, adsorption-desorption. Empirical studies rely on distribution coefficient measurements, and mechanism studies strive to identify, differentiate, and quantify the processes that control nuclide retardation. The status of sorption mechanism studies is discussed, with emphasis on delineating the usefulness of ideal ion-exchange, site-binding electrical double-layer, and redox-controlled sorption constructs. Since studies to date show greater potential for site-binding electrical double-layer models, future efforts will concentrate on this construct. Laboratory studies are discussed which corroborate the importance of redox reactions in causing nuclide retardation for multivalent elements, such as Tc, Np, Pu, and U. Results suggest that both solution-mediated reduction, such as the Fe(II)-Fe(III) couple, and solid-solution heterogeneous reduction reactions, such as reduction of solution Pu(VI) at the mineral surface by structural Fe(II), occur. Coupled microscopy, microprobe, and autoradiography studies have determined actual sorption sites for radionuclides on polymineralic rocks. The studies show that it is possible for minor phases to completely dominate the mass of radionuclides adsorbed. The most active minerals are typically alternation products (clays and zeolites). Several exercises are discussed which rank radionuclides according to their potential dose hazards. In each of the analyses discussed, the top four radionuclides are I, Tc, Np, and Ra. Other elements that rank high in potential hazards are Pu, U, Am, Th, Pb, Sn, Pd, and Se

  14. A national cohort study of parental socioeconomic status and non-fatal suicidal behaviour-the mediating role of school performance

    Directory of Open Access Journals (Sweden)

    Jablonska Beata

    2012-01-01

    Full Text Available Abstract Background A link between low parental socioeconomic status and mental health problems in offspring is well established in previous research. The mechanisms that explain this link are largely unknown. The present study investigated whether school performance was a mediating and/or moderating factor in the path between parental socioeconomic status and the risk of hospital admission for non-fatal suicidal behaviour. Methods A national cohort of 447 929 children born during 1973-1977 was followed prospectively in the National Patient Discharge Register from the end of their ninth and final year of compulsory school until 2001. Multivariate Cox proportional hazards and linear regression analyses were performed to test whether the association between parental socioeconomic status and non-fatal suicidal behaviour was mediated or moderated by school performance. Results The results of a series of multiple regression analyses, adjusted for demographic variables, revealed that school performance was as an important mediator in the relationship between parental socioeconomic status and risk of non-fatal suicidal behaviour, accounting for 60% of the variance. The hypothesized moderation of parental socioeconomic status-non-fatal suicidal behaviour relationship by school performance was not supported. Conclusions School performance is an important mediator through which parental socioeconomic status translates into a risk for non-fatal suicidal behaviour. Prevention efforts aimed to reduce socioeconomic inequalities in non-fatal suicidal behaviour among young people will need to consider socioeconomic inequalities in school performance.

  15. Status of the ATLAS Pixel Detector at the LHC and its performance after three years of operation

    CERN Document Server

    Andreazza, A; The ATLAS collaboration

    2012-01-01

    The ATLAS Pixel Detector is the innermost detector of the ATLAS experiment at the Large Hadron Collider at CERN, providing high-resolution measurements of charged particle tracks in the high radiation environment close to the collision region. This capability is vital for the identification and measurement of proper decay times of long-lived particles such as b-hadrons, and thus vital for the ATLAS physics program. The detector provides hermetic coverage with three cylindrical layers and three layers of forward and backward pixel detectors. It consists of approximately 80 million pixels that are individually read out via chips bump-bonded to 1744 n-in-n silicon substrates. In this talk, results from the successful operation of the Pixel Detector at the LHC and its status after three years of operation will be presented, including monitoring, calibration procedures, timing optimization and detector performance. The detector performance is excellent: ~96 % of the pixels are operational, noise occupancy and hit ...

  16. RHIC PC CNI POLARIMETER:STATUS AND PERFORMANCE from THE FIRST COLLIDER RUN

    International Nuclear Information System (INIS)

    JINNOUCHI, O.; ALEKSEEV, I.G.; BLAND, L.C.; BRAVAR, A.; BUNCE, G.; CADMAN, R.; DESHPANDE, A.D.; HAWAN, S.; FIELDS, D.E.; HUANG, H.; HUGHES, V.; IGO, G.; IMAI, K.; KANAVETS, V.P.; KIRYLUK, J.; KURITA, K.; LI, Z.; LOZOWSKI, W.; MACKAY, W.W.; MAKDISI, Y.; OGAWA, A.; RESCIA, S.; ROSER, T.; SAITO, N.; SPINKA, H.; SURROW, B.; SVIRIDA, D.N.; TOJO, J.; UNDERWOOD, D.; WOOD, J.

    2002-01-01

    Polarimeters using the proton carbon elastic scattering process in Coulomb Nuclear Interference (CNI) region were installed in two RHIC rings. Polarization measurements were successfully carried out with the high energy polarized proton beams for the first polarized pp collision run. The physics principles, performance, and polarization measurements are presented

  17. RHIC pC CNI Polarimeter: Status and Performance from the First Collider Run

    International Nuclear Information System (INIS)

    Jinnouchi, O.; Tojo, J.; Alekseev, I.G.; Kanavets, V.P.; Svirida, D.N.; Bland, L.C.; Bravar, A.; Huang, H.; Li, Z.; MacKay, W.W.; Makdisi, Y.; Ogawa, A.; Rescia, S.; Roser, T.; Surrow, B.; Bunce, G.; Cadman, R.; Spinka, H.; Underwood, D.; Deshpande, A.

    2003-01-01

    Polarimeters using the proton carbon elastic scattering process in Coulomb Nuclear Interference (CNI) region were installed in two RHIC rings. Polarization measurements were successfully carried out with the high energy polarized proton beams for the first polarized pp collision run. The physics principles, performance, and polarization measurements are presented

  18. Annual Status Report (FY2014) 200 West and 200 East Performance Assessments

    Energy Technology Data Exchange (ETDEWEB)

    Nichols, W. E. [CH2M Hill Plateau Remediation Company, Richland, WA (United States); Khaleel, R. [INTERA, Inc., Austin, TX (United States); Mehta, S. [CH2M Hill Plateau Remediation Company, Richland, WA (United States)

    2015-03-24

    This annual review provides the projected dose estimates of radionuclide inventories disposed in the active Low-Level Waste Burial Grounds (LLBGs) since September 26, 1988. These estimates are calculated using the original does methodology developed in the performance assessment analyses.

  19. High-Performance, Space-Storable, Bi-Propellant Program Status

    Science.gov (United States)

    Schneider, Steven J.

    2002-01-01

    Bipropellant propulsion systems currently represent the largest bus subsystem for many missions. These missions range from low Earth orbit satellite to geosynchronous communications and planetary exploration. The payoff of high performance bipropellant systems is illustrated by the fact that Aerojet Redmond has qualified a commercial NTO/MMH engine based on the high Isp technology recently delivered by this program. They are now qualifying a NTO/hydrazine version of this engine. The advanced rhenium thrust chambers recently provided by this program have raised the performance of earth storable propellants from 315 sec to 328 sec of specific impulse. The recently introduced rhenium technology is the first new technology introduced to satellite propulsion in 30 years. Typically, the lead time required to develop and qualify new chemical thruster technology is not compatible with program development schedules. These technology development programs must be supported by a long term, Base R&T Program, if the technology s to be matured. This technology program then addresses the need for high performance, storable, on-board chemical propulsion for planetary rendezvous and descent/ascent. The primary NASA customer for this technology is Space Science, which identifies this need for such programs as Mars Surface Return, Titan Explorer, Neptune Orbiter, and Europa Lander. High performance (390 sec) chemical propulsion is estimated to add 105% payload to the Mars Sample Return mission or alternatively reduce the launch mass by 33%. In many cases, the use of existing (flight heritage) propellant technology is accommodated by reducing mission objectives and/or increasing enroute travel times sacrificing the science value per unit cost of the program. Therefore, a high performance storable thruster utilizing fluorinated oxidizers with hydrazine is being developed.

  20. Performance and Fabrication Status of TREAT LEU Conversion Conceptual Design Concepts

    Energy Technology Data Exchange (ETDEWEB)

    IJ van Rooyen; SR Morrell; AE Wright; E. P Luther; K Jamison; AL Crawford; HT III Hartman

    2014-10-01

    Resumption of transient testing at the TREAT facility was approved in February 2014 to meet U.S. Department of Energy (DOE) objectives. The National Nuclear Security Administration’s Global Threat Reduction Initiative Convert Program is evaluating conversion of TREAT from its existing highly enriched uranium (HEU) core to a new core containing low enriched uranium (LEU). This paper describes briefly the initial pre-conceptual designs screening decisions with more detailed discussions on current feasibility, qualification and fabrication approaches. Feasible fabrication will be shown for a LEU fuel element assembly that can meet TREAT design, performance, and safety requirements. The statement of feasibility recognizes that further development, analysis, and testing must be completed to refine the conceptual design. Engineering challenges such as cladding oxidation, high temperature material properties, and fuel block fabrication along with neutronics performance, will be highlighted. Preliminary engineering and supply chain evaluation provided confidence that the conceptual designs can be achieved.

  1. Comparison of Performance, Meat Lipids and Oxidative Status of Pigs from Commercial Breed and Organic Crossbreed

    Directory of Open Access Journals (Sweden)

    Giuseppe Martino

    2014-06-01

    Full Text Available The aim of this research was to determine the effect of rearing systems for pig production, as concerns performance, meat lipid content, the fatty acid profile, histidinic antioxidants, coenzyme Q10, and TBARs. One hundred pigs were assigned to one of three treatments: intensively reared commercial hybrid pig (I, free range commercial hybrid pig (FR or organically reared crossbred pig (O, according to organic EU Regulations. I pigs showed the best productive performance, but FR and O increased: C20:1n9, Δ9-desaturase (C18 and thioesterase indices in meat. Lipid, dipeptides and CoQ10 appeared correlated to glycolytic and oxidative metabolic pathways. We can conclude that all studied parameters were influenced by the rearing system used, and that differences were particularly evident in the O system, which produced leaner meat with higher oxidative stability. In this respect, the organic pig rearing system promotes and enhances biodiversity, environmental sustainability and food quality.

  2. Status of compost usage and its performance on vegetable production in Monga areas of Bangladesh

    Directory of Open Access Journals (Sweden)

    G.K.M.M. Rahman

    2014-12-01

    Full Text Available The present study was carried out to assess the existing status of compost usage on vegetable production and determine the overall effect of household waste compost (HWC on growth and yield of vegetables and enhancement of soil fertility in the monga areas of Bangladesh. A field survey was conducted on 152 sampled farmers during 2010 to 2011. Questionnaire containing both closed and open-ended questions were used to assess existing production practices of vegetables using compost in both homestead and field conditions. Three field trials at Badargonj and Kawnia upazilas of Rangpur district were conducted taking four treatments i.e. control, recommended doses (RD of fertilizers, HWC at the rate of 10 tha-1, and HWC 10 t ha-1 plus RD as IPNS based with Lal shak, Palong shak, Pui shak and Tomato. Base line survey results indicated inadequate knowledge of the farmers on use and preparation of the household waste compost. Yield data of all vegetables i.e. Tomato, Lal shak, Palong shak and Pui shak indicated that the combined application of nutrients using organic and inorganic sources were significantly better than that of solitary application of inorganic fertilizers. The potential of household waste compost applied @ 10 t ha-1 along with inorganic fertilizers applied was found highly satisfactory in producing Tomato, where yield was recorded 75 t ha-1 in the study area. The fresh yield of Palong shak was found 16 t ha-1 when recommended doses of inorganic fertilizers were applied, but it was about 19 t ha-1 under combined application of HWC @ 10 t ha-1 and inorganic fertilizers following IPNS concept. The fresh yield of Pui shak was found about 49 t ha-1 under combined application of organic and inorganic nutrients. Considering the availability and costs of different composts, it is evinced that HWC contained good amount of NPK which indicates its potentiality to be used as a soil amendment, improving soil fertility and crop productivity. It can be

  3. Managing Inclusiveness and Diversity in Teams: How Leader Inclusiveness Affects Performance through Status and Team Identity

    OpenAIRE

    Mitchell, Rebecca; Boyle, Brendan; Parker, Vicki; Giles, Michelle; Chiang, Vico; Joyce, Pauline

    2015-01-01

    While there is increasing pressure to work collaboratively in interprofessional teams, health professionals often continue to operate in uni-professional silos. Leader inclusiveness is directed toward encouraging and valuing the different viewpoints of diverse members within team interactions, and has significant potential to overcome barriers to interprofessional team performance. In order to better understand the influence of leader inclusiveness, we develop and investigate a model of its e...

  4. The CMS electromagnetic calorimeter: status, performance with cosmic and first LHC data

    CERN Document Server

    Biino, Cristina

    2009-01-01

    The design goal for ECAL is the potential to discover a neutral Higgs boson in the low mass region by measuring the decay into two photons. For a low mass Higgs the intrinsic decay width is very small, therefore the measured width precition is dominated by the ECAL energy resolution. This has led to a target energy resolution of 0.5% for electrons and photons above 100 GeV. The design and performance o...

  5. Implementation status of performance demonstration program for steam generator tubing analysts in Korea

    International Nuclear Information System (INIS)

    Cho, Chan Hee; Lee, Hee Jong; Yoo, Hyun Ju; Nam, Min Woo; Hong, Sung Yull

    2013-01-01

    Some essential components in nuclear power plants are periodically inspected using non destructive examinations, for example ultrasonic, eddy current and radiographic examinations, in order to determine their integrity. These components include nuclear power plant items such as vessels, containments, piping systems, pumps, valves, tubes and core support structure. Steam generator tubes have an important safety role because they constitute one of the primary barriers between the radioactive and non radioactive sides of the nuclear power plant. There is potential that if a tube bursts while a plant is operating, radioactivity from the primary coolant system could escape directly to the atmosphere. Therefore, in service inspections are critical in maintaining steam generator tube integrity. In general, the eddy current testing is widely used for the inspection of steam generator tubes due tube integrity. In general, the eddy current testing is widely used for the inspection of steam generator tubes due to its high inspection speed and flaw detectability on non magnetic tubes. However, it is not easy to analyze correctly eddy current signals because they are influenced by many factors. Therefore, the performance of eddy current data analysts for steam generator tubing should be demonstrated comprehensively. In Korea, the performance of steam generator tubing analysts has been demonstrated using the Qualified Data Analyst program. This paper describes the performance demonstration program for steam generator tubing analysts and its implementation results in Korea. The pass rate of domestic analysts for this program was 71.4%

  6. Effect of selenium supplementation on pigeon reproductive performance, selenium concentration and antioxidant status.

    Science.gov (United States)

    Wang, Y; Yang, H M; Cao, W; Li, Y B

    2017-09-01

    The effects of dietary supplementation of sodium selenite (SS) on the reproductive performance and the concentration of selenium, glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), and malondialdehyde (MDA) were determined, and expression of glutathione peroxidase 4 (GPx4) and bone morphogenic protein 15 (BMP15) was evaluated. Paired pigeons (n = 864) were fed: T1 received no SS, while T2, T3, and T4 received 0.5, 1.0, and 1.5 mg of SS/kg of dry matter (DM), respectively. Treatments were performed in triplicate with 72 pairs in each replicate. The results showed that selenium supplementation significantly affected pigeon reproductive performance. Birds fed 1.0 mg of SS/kg displayed higher egg production (P > 0.05), higher birth rate, and lower dead sperm rate than the control group (P Selenium and biochemical analyses revealed a higher selenium concentration in the 1.5 mg of SS/kg group than in the control group (P  0.05); however, in plasma, MDA was lower in the control group (P  0.05), while in ovary, BMP15 was down-regulated in the 1.5 mg of SS/kg group (P selenium concentration, and 0.5 mg of SS/kg up-regulated GSH-Px activity. © 2017 Poultry Science Association Inc.

  7. Status report on the R and D studies performed in Italy for fast reactor seismic analysis

    International Nuclear Information System (INIS)

    Martelli, A.; Cecchini, F.; Forni, M.

    1988-01-01

    After some notes on the high levels of the design earthquakes adopted for PEC and the important features of this reactor (making it particularly sensitive to seismic excitation), this paper presents the fundamentals of the numerical and experimental studies that were carried out by ENEA in co-operation with ANSALDO, ISMES and AGIP for the PEC seismic verification. More precisely, the paper focuses on the wide-ranging research and development programme that has been performed (and recently completed) on the reactor building, the reactor-block, the main vessel, the core and the shutdown system. The needs of these detailed studies are stressed and the feed-back on the PEC design, necessary to satisfy the seismic safety requirements, are recalled. The general validity of the analyses in the framework of the research and development activities for fast reactors is also pointed out. Some notes on piping studies and LMFBR component analysis performed in Italy are also contained: in this framework, seismic tests performed on a SPX-1 primary pump shaft in the CPV-1 test rig at the ENEA Center of Brasimone are recalled. (author). 20 refs, 17 figs

  8. Implementation status of performance demonstration program for steam generator tubing analysts in Korea

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Chan Hee; Lee, Hee Jong; Yoo, Hyun Ju; Nam, Min Woo [KHNP Central Research Institute, Daejeon (Korea, Republic of); Hong, Sung Yull [Yeungnam Univ., Gyeongsan (Korea, Republic of)

    2013-02-15

    Some essential components in nuclear power plants are periodically inspected using non destructive examinations, for example ultrasonic, eddy current and radiographic examinations, in order to determine their integrity. These components include nuclear power plant items such as vessels, containments, piping systems, pumps, valves, tubes and core support structure. Steam generator tubes have an important safety role because they constitute one of the primary barriers between the radioactive and non radioactive sides of the nuclear power plant. There is potential that if a tube bursts while a plant is operating, radioactivity from the primary coolant system could escape directly to the atmosphere. Therefore, in service inspections are critical in maintaining steam generator tube integrity. In general, the eddy current testing is widely used for the inspection of steam generator tubes due tube integrity. In general, the eddy current testing is widely used for the inspection of steam generator tubes due to its high inspection speed and flaw detectability on non magnetic tubes. However, it is not easy to analyze correctly eddy current signals because they are influenced by many factors. Therefore, the performance of eddy current data analysts for steam generator tubing should be demonstrated comprehensively. In Korea, the performance of steam generator tubing analysts has been demonstrated using the Qualified Data Analyst program. This paper describes the performance demonstration program for steam generator tubing analysts and its implementation results in Korea. The pass rate of domestic analysts for this program was 71.4%.

  9. Distinguishing Playing Status Through a Functionally Relevant Performance Measure in Female Division I Collegiate Soccer Athletes.

    Science.gov (United States)

    Magrini, Mitchel A; Colquhoun, Ryan J; Sellers, John H; Conchola, Eric C; Hester, Garrett M; Thiele, Ryan M; Pope, Zach K; Smith, Doug B

    2017-06-08

    Although soccer is predominately an endurance sport, high velocity movements may be an important indicator of athletic success. The purpose of this investigation was to establish whether squat jumps (SJ) can differentiate starters from non-starters with a female collegiate division I soccer team. Eighteen female division I soccer athletes were separated into two groups: 9 starters (age: 19.5 ± 1.0; mass = 64.8 ± 11.5 kg; height = 167.5 ± 7.7 cm; games started = 18.2 ± 4.7; minutes played = 1633.8 ± 478.2 min) and 9 non-starters (age: 19.4 ± 1.4 years; mass = 63.3 ± 4.2 kg; height = 164.7 ± 6.8 cm; games started 0.7 ± 1.3; minutes played 158.2 ± 269.3). Each athlete performed 3 maximal SJs at a starting knee angle of 110° without arm swing. Each participant's SJ height, mean power (MP), peak power (PP), mean velocity (MV), and peak velocity (PV) were measured during each attempt by a linear position transducer (LPT). No statistically significant differences (p ≥ 0.05) in MP and PP between the starters and non-starters were observed. However, starters performed significantly better than non-starters in SJ height (p = 0.002), MV (p = 0.025), and PV (p = 0.015). Additionally, SJ height was strongly correlated with MV (r = 0.628) and PV (r = 0.647). These findings suggest that SJ height, MV and PV, may be important variables for discriminating differences between starters and non-starters in division I female soccer athletes and a strong indicator of explosive performance.

  10. Voluntary fluid intake, hydration status, and aerobic performance of adolescent athletes in the heat.

    Science.gov (United States)

    Wilk, Boguslaw; Timmons, Brian W; Bar-Or, Oded

    2010-12-01

    We determined whether beverage flavoring and composition would stimulate voluntary drink intake, prevent dehydration, and maintain exercise performance in heat-acclimated adolescent males running in the heat. Eight adolescent (age, 13.7 ± 1.1 years) runners (peak oxygen uptake, 59.5 ± 4.0 mL·kg-1·min-1) underwent at least four 80-min exercise heat-acclimation sessions before completing 3 experimental sessions. All sessions were performed at 30 °C and 60%-65% relative humidity. Each experimental session consisted of five 15-min treadmill runs at a speed eliciting 65% peak oxygen uptake, with a 5 min rest prior to each run. Ten minutes after the final run, a time to exhaustion test was performed at a speed eliciting 90% peak oxygen uptake. Counterbalanced experimental sessions were identical, except for fluid intake, which consisted of tap water (W), flavored water (FW), and FW with 6% carbohydrate and 18 mmol·L-1 NaCl (CNa) consumed ad libitum. Fluid intake and body weight were monitored to calculate dehydration. Voluntary fluid intake was similar to fluid losses in W (1032 ± 130 vs. 1340 ± 246 g), FW (1086 ± 86 vs. 1451 ± 253 g), and CNa (1259 ± 119 vs. 1358 ± 234 g). As a result, significant dehydration was avoided in all trials (-0.45% ± 0.68% body weight in W, -0.66% ± 0.50% body weight in FW, and -0.13% ± 0.71% body weight in CNa). Core temperature increased by ~1 °C during exercise, but was not different between trials. Time to exhaustion was not different between trials and averaged 8.8 ± 1.7 min. Under exercise conditions more closely reflecting real-life situations, heat-acclimatized adolescent male runners can appropriately gauge fluid intake regardless of the type of beverage made available, resulting in consistency in exercise performance.

  11. Status, performance, and first results of the IceTop array

    Energy Technology Data Exchange (ETDEWEB)

    Stanev, Todor [Bartol Research Institute, Department of Physics and Astronomy, University of Delaware, Newark, DE 19716 (United States)

    2009-12-15

    We describe the design and performance of IceTop, the air shower array on top of the IceCube neutrino detector. After the 2008/09 antarctic summer season both detectors are deployed at almost 3/4 of their design size. With the current IceTop 59 stations we can start the study of showers of energy well above 10{sup 17}eV. The paper also describes the first results from IceTop and our plans to study the cosmic ray composition using several different types of analysis.

  12. The status of ANSI N13.11 - The dosimeter performance test standard

    International Nuclear Information System (INIS)

    Sims, C.S.

    1991-01-01

    The standard designated ANSI N13.11 was issued in 1983 and is the basis for the dosimeter performance test associated with the National Voluntary Laboratory Accreditation Program (NVLAP). The standard is important because the Nuclear Regulatory Commission requires that all licensees use personnel dosimeters processed by NVLAP-accredited processors. The standard has undergone review and modifications have been recommended. Historical information concerning the development and utilization of the present standard, ANSI N13.11-1983, is presented. Details associated with the review of the standard (e.g., policy, group selection) are then given. Finally, the modifications recommended by the review group are discussed

  13. Chemotherapy-Related Toxicity, Nutritional Status and Quality of Life in Precachectic Oncologic Patients with, or without, High Protein Nutritional Support. A Prospective, Randomized Study.

    Science.gov (United States)

    Ziętarska, Monika; Krawczyk-Lipiec, Joanna; Kraj, Leszek; Zaucha, Renata; Małgorzewicz, Sylwia

    2017-10-11

    Cancer disease is usually associated with impaired nutritional status, which is one of the factors contributing to deterioration of the results of surgery, chemotherapy or radiotherapy. The aim of the study was to determine whether nutritional support with high protein (ONS) in adult oncologic patients in the first step of cancer cachexia-asymptomatic precachexia, has an influence on the toxicity of systemic therapy. However, secondary endpoints were established: to determine whether high protein ONS influences the nutritional status, the quality of life, and the performance status. A total of 114 persons aged 40-84 years old with colorectal cancer were examined. Based on the randomization, 47 patients were qualified to the interventional group (ONS group) and 48 to Control group. To evaluate the nutritional status NRS-2002 (Nutritional Risk Screening), SGA (Subjective Global Assessment), SCRINIO (SCReenIng the Nutritional status In Oncology) Working Group classification, VAS (Visual Analog Scale) for appetite was used. FAACT (Functional Assessment of Anorexia/Cachexia Therapy) questionnaire was used for assessment of the quality of life. The health status of patients was evaluated based on the Karnofsky Performance Scale. Anthropometric measurements were done. Severe complications of chemotherapy, which caused the end of treatment, a slight complication of the gastrointestinal tract such as diarrhea grade 2 according to ECOG (Eastern Cooperative Oncology Group) score regardless of the studied group, were observed. There were no statistical differences in the number and severity of the observed complications, i.e., neutropenia, leucopenia, thrombocytopenia, anemia, abdominal pain, nausea and vomiting, and diarrhea. During the follow-up the significant changes of SGA, VAS, albumin and prealbumin were observed between groups. In the ONS group an improvement in nutritional status was noticed (increased appetite VAS, p = 0.05; increased points in SGA, p = 0.015, and

  14. Chemotherapy-Related Toxicity, Nutritional Status and Quality of Life in Precachectic Oncologic Patients with, or without, High Protein Nutritional Support. A Prospective, Randomized Study

    Directory of Open Access Journals (Sweden)

    Monika Ziętarska

    2017-10-01

    Full Text Available Background: Cancer disease is usually associated with impaired nutritional status, which is one of the factors contributing to deterioration of the results of surgery, chemotherapy or radiotherapy. Objectives: The aim of the study was to determine whether nutritional support with high protein (ONS in adult oncologic patients in the first step of cancer cachexia—asymptomatic precachexia, has an influence on the toxicity of systemic therapy. However, secondary endpoints were established: to determine whether high protein ONS influences the nutritional status, the quality of life, and the performance status. Materials and Methods: A total of 114 persons aged 40–84 years old with colorectal cancer were examined. Based on the randomization, 47 patients were qualified to the interventional group (ONS group and 48 to Control group. To evaluate the nutritional status NRS-2002 (Nutritional Risk Screening, SGA (Subjective Global Assessment, SCRINIO (SCReenIng the Nutritional status In Oncology Working Group classification, VAS (Visual Analog Scale for appetite was used. FAACT (Functional Assessment of Anorexia/Cachexia Therapy questionnaire was used for assessment of the quality of life. The health status of patients was evaluated based on the Karnofsky Performance Scale. Anthropometric measurements were done. Results: Severe complications of chemotherapy, which caused the end of treatment, a slight complication of the gastrointestinal tract such as diarrhea grade 2 according to ECOG (Eastern Cooperative Oncology Group score regardless of the studied group, were observed. There were no statistical differences in the number and severity of the observed complications, i.e., neutropenia, leucopenia, thrombocytopenia, anemia, abdominal pain, nausea and vomiting, and diarrhea. During the follow-up the significant changes of SGA, VAS, albumin and prealbumin were observed between groups. In the ONS group an improvement in nutritional status was noticed

  15. The LHCb RICH system: current detector performance and status of the upgrade program

    CERN Document Server

    Fiorini, Massimiliano

    2016-01-01

    LHCb is a precision experiment devoted to the study of CP violation and rare decays of b and c quarks, and to the search for new physics beyond the Standard Model at the Large Hadron Collider (LHC) at CERN. The Ring-Imaging Cherenkov (RICH) system is a key component of the LHCb experiment: it consists of two RICH detectors that provide charged particle identification over a wide momentum range (2-100 GeV/c) and angular acceptance (15-300 mrad). The LHCb RICH system has been performing extremely well during Run 1 and is providing the LHCb experiment also in Run 2 with a robust, reliable and precise particle identification system. Performance of the RICH detectors measured from data will be presented, with special reference to its dependence on calibration parameters and event multiplicities. The LHCb experiment is preparing for an upgrade during the second LHC long shutdown (2019-2020) in order to fully exploit the LHC flavour physics potential. A five-fold increase in instantaneous luminosity is foreseen reac...

  16. Eleventh interim status report: Model 9975 O-Ring fixture long-term leak performance

    Energy Technology Data Exchange (ETDEWEB)

    Daugherty, W. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-08-01

    A series of experiments to monitor the aging performance of Viton® GLT O-rings used in the Model 9975 package has been ongoing since 2004 at the Savannah River National Laboratory. One approach has been to periodically evaluate the leak performance of O-rings being aged in mock-up 9975 Primary Containment Vessels (PCVs) at elevated temperature. Other methods such as compression-stress relaxation (CSR) tests and field surveillance are also on-going to evaluate O-ring behavior. Seventy tests using PCV mock-ups were assembled and heated to temperatures ranging from 200 to 450 ºF. They were leak-tested initially and have been tested periodically to determine if they continue to meet the leak-tightness criterion defined in ANSI standard N14.5-97. Due to material substitution, fourteen additional tests were initiated in 2008 with GLT-S O-rings heated to temperatures ranging from 200 to 400 ºF.

  17. Time of Day and Training Status Both Impact the Efficacy of Caffeine for Short Duration Cycling Performance

    Directory of Open Access Journals (Sweden)

    James C. Boyett

    2016-10-01

    Full Text Available This project was designed to assess the effects of time of day and training status on the benefits of caffeine supplementation for cycling performance. Twenty male subjects (Age, 25 years; Peak oxygen consumption, 57 mL·kg−1·min−1 were divided into tertiles based on training levels, with top and bottom tertiles designated as ‘trained’ (n = 7 and ‘untrained’ (n = 7. Subjects completed two familiarization trials and four experimental trials consisting of a computer-simulated 3-km cycling time trial (TT. The trials were performed in randomized order for each combination of time of day (morning and evening and treatment (6mg/kg of caffeine or placebo. Magnitude-based inferences were used to evaluate all treatment effects. For all subjects, caffeine enhanced TT performance in the morning (2.3% ± 1.7%, ‘very likely’ and evening (1.4% ± 1.1%, ‘likely’. Both untrained and trained subjects improved performance with caffeine supplementation in the morning (5.5% ± 4.3%, ‘likely’; 1.0% ± 1.7%, ‘likely’, respectively, but only untrained subjects rode faster in the evening (2.9% ± 2.6%, ‘likely’. Altogether, our observations indicate that trained athletes are more likely to derive ergogenic effects from caffeine in the morning than the evening. Further, untrained individuals appear to receive larger gains from caffeine in the evening than their trained counterparts.

  18. Time of Day and Training Status Both Impact the Efficacy of Caffeine for Short Duration Cycling Performance.

    Science.gov (United States)

    Boyett, James C; Giersch, Gabrielle E W; Womack, Christopher J; Saunders, Michael J; Hughey, Christine A; Daley, Hannah M; Luden, Nicholas D

    2016-10-14

    This project was designed to assess the effects of time of day and training status on the benefits of caffeine supplementation for cycling performance. Twenty male subjects (Age, 25 years; Peak oxygen consumption, 57 mL·kg -1 ·min -1 ) were divided into tertiles based on training levels, with top and bottom tertiles designated as 'trained' ( n = 7) and 'untrained' ( n = 7). Subjects completed two familiarization trials and four experimental trials consisting of a computer-simulated 3-km cycling time trial (TT). The trials were performed in randomized order for each combination of time of day (morning and evening) and treatment (6mg/kg of caffeine or placebo). Magnitude-based inferences were used to evaluate all treatment effects. For all subjects, caffeine enhanced TT performance in the morning (2.3% ± 1.7%, 'very likely') and evening (1.4% ± 1.1%, 'likely'). Both untrained and trained subjects improved performance with caffeine supplementation in the morning (5.5% ± 4.3%, 'likely'; 1.0% ± 1.7%, 'likely', respectively), but only untrained subjects rode faster in the evening (2.9% ± 2.6%, 'likely'). Altogether, our observations indicate that trained athletes are more likely to derive ergogenic effects from caffeine in the morning than the evening. Further, untrained individuals appear to receive larger gains from caffeine in the evening than their trained counterparts.

  19. Personality characteristics and affective status related to cognitive test performance and gender in patients with memory complaints.

    Science.gov (United States)

    Vestberg, Susanna; Passant, Ulla; Risberg, Jarl; Elfgren, Christina

    2007-11-01

    The aims are to study personality characteristics of patients with memory complaints and to assess the presence of objective (OMI) versus subjective (SMI) memory impairment, the affective status, as well as potential gender differences. The patients were assessed by means of a neuropsychiatric examination and a neuropsychological test-battery. The Swedish version of the revised NEO Personality Inventory (NEO PI-R) and the Hospital Anxiety and Depression Scale (HADS) were used. The 57 patients (38 women, 19 men, mean age 56.9) differed from the Swedish normative group in three of the five personality factors: neuroticism, extraversion and agreeableness. This was mainly because of the scores of the female patients. Approximately half of the patients had OMI. No differences regarding personality factors or affective status were found between OMI and SMI patients. The female patients scored significantly higher than the male patients on symptoms of anxiety and depression. Neuroticism and symptoms of depression interacted with memory performance and gender. Our findings demonstrate the importance of applying an objective assessment of memory functions and a gender perspective when studying patients with memory complaints.

  20. Weight Status and Differences in Mobility Performance, Pain Symptoms, and Physical Activity in Older, Knee Osteoarthritis Patients

    Directory of Open Access Journals (Sweden)

    Matthew J. Garver

    2014-01-01

    Full Text Available Knee osteoarthritis (OA is a leading cause of functional disability among American adults. Obesity is a strong independent risk factor for OA. While research emphasizes the role of obesity in the OA-physical function relationship, the extent to which weight status impacts salient physical, health, and pain measures in older, knee OA patients is not well delineated. The primary aim of this study was to assess differences in mobility performance (stair climb and 400-meter walk, mobility-related self-efficacy, pain symptoms (WOMAC, and measures of accelerometer-determined physical activity (PA as a function of weight status. Analysis of covariance was conducted to examine differences on the dependent variables. Obese class III patients were outperformed by their counterparts on nearly every measure of mobility, mobility-related self-efficacy, and the assessment of pain symptoms. These outcomes did not differ among other weight comparisons. Normal weight subjects outperformed classes I, II, and III counterparts on most measures of PA (engagement in moderate or greater PA and total weekly steps. Additionally, overweight participants outperformed obese class II participants and obese class I participants outperformed obese classes II and III participants on total weekly steps. Collectively, these findings underscore the meaningful differences observed in relevant OA outcomes as a function of increasing levels of body weight.

  1. Cognitively-Impaired-Not-Demented Status Moderates the Time-Varying Association between Finger Tapping Inconsistency and Executive Performance.

    Science.gov (United States)

    Halliday, Drew W R; Stawski, Robert S; MacDonald, Stuart W S

    2017-02-01

    Response time inconsistency (RTI) in cognitive performance predicts deleterious health outcomes in late-life; however, RTI estimates are often confounded by additional influences (e.g., individual differences in learning). Finger tapping is a basic sensorimotor measure largely independent of higher-order cognition that may circumvent such confounds of RTI estimates. We examined the within-person coupling of finger-tapping mean and RTI on working memory, and the moderation of these associations by cognitive status. A total of 262 older adults were recruited and classified as controls, cognitively-impaired-not-demented (CIND) unstable or CIND stable. Participants completed finger-tapping and working-memory tasks during multiple weekly assessments, repeated annually for 4 years. Within-person coupling estimates from multilevel models indicated that on occasions when RTI was greater, working-memory response latency was slower for the CIND-stable, but not for the CIND-unstable or control individuals. The finger-tapping task shows potential for minimizing confounds on RTI estimates, and for yielding RTI estimates sensitive to central nervous system function and cognitive status. © The Author 2016. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  2. Performance comparison of machine learning methods for prognosis of hormone receptor status in breast cancer tissue samples.

    Science.gov (United States)

    Kalinli, Adem; Sarikoc, Fatih; Akgun, Hulya; Ozturk, Figen

    2013-06-01

    We examined the classification and prognostic scoring performances of several computer methods on different feature sets to obtain objective and reproducible analysis of estrogen receptor status in breast cancer tissue samples. Radial basis function network, k-nearest neighborhood search, support vector machines, naive bayes, functional trees, and k-means clustering algorithm were applied to the test datasets. Several features were employed and the classification accuracies of each method for these features were examined. The assessment results of the methods on test images were also experimentally compared with those of two experts. According to the results of our experimental work, a combination of functional trees and the naive bayes classifier gave the best prognostic scores indicating very good kappa agreement values (κ=0.899 and κ=0.949, p<0.001) with the experts. This combination also gave the best dichotomization rate (96.3%) for assessment of estrogen receptor status. Wavelet color features provided better classification accuracy than Laws texture energy and co-occurrence matrix features. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  3. Status of the ATLAS Pixel Detector and its performance after three years of operation

    CERN Document Server

    Favareto, A; The ATLAS collaboration

    2012-01-01

    The ATLAS Pixel Detector is the innermost detector of the ATLAS experiment at the Large Hadron Collider at CERN, providing high-resolution measurements of charged particle tracks in the high radiation environment close to the collision region. This capability is very important for the identification and measurement of proper decay times of long-lived particles such as b-hadrons, and thus vital for the ATLAS physics program. The detector provides hermetic coverage with three cylindrical layers and three layers of forward and backward pixel detectors. It consists of approximately 80 million pixels that are individually read out via chips bump-bonded to 1744 n-in-n silicon substrates. The detector performance is excellent: ~96 % of the pixels are operational, noise occupancy and hit efficiency exceed the design specification, and a good alignment allows high quality track resolution

  4. Status of the ATLAS Pixel Detector and its performance after three years of operation

    CERN Document Server

    Favareto, A; The ATLAS collaboration

    2012-01-01

    The ATLAS Pixel Detector is the innermost detector of the ATLAS experiment at the Large Hadron Collider at CERN, providing high-resolution measurements of charged particle tracks in the high radiation environment close to the collision region. This capability is very important for the identification and measurement of proper decay times of long-lived particles such as b-hadrons, and thus vital for the ATLAS physics program. The detector provides hermetic coverage with three cylindrical layers and three layers of forward and backward pixel detectors. It consists of approximately 80 million pixels that are individually read out via chips bump-bonded to 1744 n-in-n silicon substrates. The detector performance is excellent: ~96% of the pixels are operational, noise occupancy and hit efficiency exceed the design specification, and a good alignment allows high quality track resolution.

  5. Status of assessment tools on the performance guarantee contents of backfill, bulkhead, tunnel and pit

    International Nuclear Information System (INIS)

    Kawakami, Susumu; Fujita, Tomoo; Yui, Mikazu

    2006-03-01

    In order to contribute to the safety standards and guidelines which a regulator will decide, a state-of-the-art assessment method is investigated and summarized in tables about performance guarantee contents of backfill, bulkhead, tunnel (access, main, connecting, disposal) and disposal pit. In addition, examples of assessment tools are described. In this report, summary of (1) basic properties of bentonite, including swelling, mechanical and hydraulic properties, (2) long-term behavior of bentonite, including extrusion/erosion into host rock, and alteration, (3) effect of high pH plume from cementitious material and (4) mechanical stability of the near-field is described. Check points, assessment methods for (based on the data obtained from the experimental results, the estimation value obtained from empirical equations and database, and the modeling calculations) and latest results of these R and D programs were also summarized. (author)

  6. THE EFFECT OF DIETARY SUPPLEMENTATION OF HERBAL EXTRACTS ON GROWTH PERFORMANCE AND HEALTH STATUS OF RABBITS

    Directory of Open Access Journals (Sweden)

    Mária Chrenková

    2013-02-01

    Full Text Available Seventy two rabbits (Hycole, (♂+♀ 5 weeks old were divided into 2 experimental (EG and one control (CG group. The feed mixture A in control (CG did not contain any coccidiostat. In the first experimental group (EG1 was tested a complete granulated mixture B enriched with 30 g dry extract Eleutherococcus senticosus per 100 kg mixture. The animals were fed mixture B in combination with probiotic strain Enterococcus faecium EF AL 41 applied orally at a dose (10 9 CFU. ml-1 500 μl per animal in drinking water during 21 days. In the second group (EG2 was tested complete granulated mixture B. The experiment lasted 42 days. Body weight and feed consumption were registered weekly. Samples of faeces were taken at days 1, 21 and 42 to monitor the counts and effect of natural substances. Blood samples were also taken to check biochemical parameters using commercial kits. The samples for microbiological analyses were treated by the standard microbiological method according to ISO with appropriate media. Results presented in this study introduce different mechanisms of action for different classes of feed additives and how these may influence the observed live performance benefits. Application of Eleutherococcus extract in combination with EF AL 41 strain in rabbits was beneficial for performance. Additives reduced counts of S. aureus and Clostridium-like sp in faeces. Bioactive substances can be beneficial for animal health as was repeatedly confirmed by our results (mortality in EG1- 12%, EG2 - 8% compared to CG- 17%.

  7. Effect of a multiple-micronutrient-fortified fruit powder beverage on the nutrition status, physical fitness, and cognitive performance of schoolchildren in the Philippines.

    Science.gov (United States)

    Solon, Florentino S; Sarol, Jesus N; Bernardo, Allan B I; Solon, Juan Antonio A; Mehansho, Haile; Sanchez-Fermin, Liza E; Wambangco, Lorena S; Juhlin, Kenton D

    2003-12-01

    This study aimed to determine the effect of a multiple-micronutrient-fortified beverage on the micronutrient status, physical fitness, and cognitive performance of schoolchildren. The study was a randomized, double-blind, placebo-controlled trial of schoolchildren assigned to receive either the fortified or nonfortified beverage with or without anthelmintic therapy. Data on hemoglobin level, urinary iodine excretion (UIE) level, physical fitness, and cognitive performance were collected at baseline and at 16 weeks post-intervention. The fortified beverage significantly improved iron status among the subjects that had hemoglobin levels performance (nonverbal mental ability score). The study showed that consumption of a multiple-micronutrient-fortified beverage for 16 weeks had significant effects on iron status, iodine status, physical fitness, and cognitive performance among iron- and/or iodine-deficient Filipino schoolchildren. Anthelmintic therapy improved iron status of anemic children and iodine status of the iron-adequate children at baseline but it had no effect on physical fitness and cognitive performance. The results from the clinical study showed that a multiple-micronutrient-fortified beverage could play an important role in preventing and controlling micronutrient deficiencies.

  8. Fifth Interim Status Report: Model 9975 PCV O-Ring Fixture Long-Term Leak Performance

    International Nuclear Information System (INIS)

    Daugherty, W.; Hoffman, E.

    2010-01-01

    A series of experiments to monitor the aging performance of Viton reg. GLT O-rings used in the Model 9975 package has been ongoing for six years at the Savannah River National Laboratory. Sixty-seven mock-ups of 9975 Primary Containment Vessels (PCVs) were assembled and heated to temperatures ranging from 200 to 450 F. They were leak-tested initially and have been tested at nominal six month intervals to determine if they meet the criterion of leaktightness defined in ANSI standard N14.5-97. Fourteen additional tests were initiated in 2008 with GLT-S O-rings heated to temperatures ranging from 200 to 400 F. High temperature aging continues for 36 GLT O-ring fixtures at 200--350 F. Room temperature leak test failures have been experienced in 5 of the GLT O-ring fixtures aging at 300 and 350 F, and in all 3 of the GLT O-ring fixtures aging at higher temperatures. No failures have yet been observed in GLT O-ring fixtures aging at 200 F for 30--48 months, which is still bounding to O-ring temperatures during storage in KAMS. High temperature aging continues for 6 GLT-S O-ring fixtures at 200--300 F. Room temperature leak test failures have been experienced in all 8 of the GLT-S O-ring fixtures aging at 350 and 400 F. No failures have yet been observed in GLT-S O-ring fixtures aging at 200 or 300 F for 19 months. For O-ring fixtures that have failed the room temperature leak test and been disassembled, the O-rings displayed a compression set ranging from 51--95%. This is significantly greater than seen to date for packages inspected during KAMS field surveillance (23% average). For GLT O-rings, service life based on the room temperature leak rate criterion is comparable to that predicted by compression stress relaxation (CSR) data at higher temperatures (350--400 F). While there are no comparable failure data yet at aging temperatures below 300 F, extrapolations of the data for GLT O-rings suggests that CSR model predictions provide a conservative prediction of service

  9. Fundamental motor skills, nutritional status, perceived competence, and school performance of Brazilian children in social vulnerability: Gender comparison.

    Science.gov (United States)

    Nobre, Glauber Carvalho; Valentini, Nadia Cristina; Nobre, Francisco Salviano Sales

    2018-06-01

    Being at risk or in social vulnerability situations can affect important aspects of child development. The aim of this study was to investigate fundamental motor skills (locomotor and object control) and school (writing, arithmetic, reading) performances, the perceived competence and the nutritional status of girls and boys living in social vulnerability in the poorest regions of Brazil. Two hundred eleven (211) children (87 girls, 41%), 7-10-year-old (M = 8.3, SD = 0.9), from public schools in Ceará (Brazil), living in social vulnerability, participated in the study. Children were assessed using the Test of Gross Motor Development - 2, the Body Mass Index (BMI), the Self-Perception Profile for Children, and the School Performance Test. Multivariate analysis of covariance (MANCOVA), adjusted for age, did not show any significant effect for locomotion. There was an effect of gender on the object control. Boys showed higher scores in striking, kicking, throwing, and rolling a ball. Quade's nonparametric analysis showed no difference in BMI between the genders. Most children presented healthy weight. The MANCOVA showed no effect of gender on children's scores on perceived competence on the subscales; moderate scores were found for most children. There were no gender effects on school performance; both boys and girls demonstrated inferior performance. Boys and girls in social vulnerability showed inferior performance in most motor skills, moderate perceived competence and inferior school performance. These results reveal that the appropriate development of these children is at risk and that intervention strategies should be implemented to compensate the difficulties presented. Copyright © 2018 Elsevier Ltd. All rights reserved.

  10. The Effects of Two Different Cleaning and Disinfection Programs on Broiler Performance and Microbiological Status of Broiler Houses

    Directory of Open Access Journals (Sweden)

    MFC Burbarelli

    2015-12-01

    Full Text Available ABSTRACT The objective of this study was to investigate the influence of two cleaning and disinfection programs on broiler performance and on the microbiological status of the facilities. This trial was an observational study of comparative character. Two experiments were conducted, with 960 birds each. Both experiments were carried out in a positive-pressure broiler house. Broilers were distributed in pens equipped with a bell drinker and a tube feeder each. In the first experiment, new wood shavings were used as litter material, and in the second, reused wood shavings were used. Two treatments with16 replicates of 30 birds each were evaluated. The regular treatment consisted of dry and wet organic matter removal, followed by washing. The European treatment consisted of dry organic matter removal, humidification, washing with water under high pressure, detergent application, rinsing, and application of two combined disinfectants: glutaraldehyde 250g/L + formaldehyde 185g/L; p-chlor-m-cresol 210 g/L. Biosecurity measures were adopted during daily management tasks to prevent cross contamination between treatments. The effectiveness of the treatments was evaluated by microbiological analysis performed before and after treatment applications, as well as by broiler performance results. Live performance results were similar between both treatments when broilers were reared on new litter. When reused word-shavings were used as litter material, the European treatment promoted better broiler performance. The European treatment was more effective than the regular treatment in reducing total microbial counts in the facilities when reused wood shavings were used as litter material, and positively influenced broiler performance.

  11. Breakfast habits, nutritional status, body weight, and academic performance in children and adolescents.

    Science.gov (United States)

    Rampersaud, Gail C; Pereira, Mark A; Girard, Beverly L; Adams, Judi; Metzl, Jordan D

    2005-05-01

    Breakfast has been labeled the most important meal of the day, but are there data to support this claim? We summarized the results of 47 studies examining the association of breakfast consumption with nutritional adequacy (nine studies), body weight (16 studies), and academic performance (22 studies) in children and adolescents. Breakfast skipping is highly prevalent in the United States and Europe (10% to 30%), depending on age group, population, and definition. Although the quality of breakfast was variable within and between studies, children who reported eating breakfast on a consistent basis tended to have superior nutritional profiles than their breakfast-skipping peers. Breakfast eaters generally consumed more daily calories yet were less likely to be overweight, although not all studies associated breakfast skipping with overweight. Evidence suggests that breakfast consumption may improve cognitive function related to memory, test grades, and school attendance. Breakfast as part of a healthful diet and lifestyle can positively impact children's health and well-being. Parents should be encouraged to provide breakfast for their children or explore the availability of a school breakfast program. We advocate consumption of a healthful breakfast on a daily basis consisting of a variety of foods, especially high-fiber and nutrient-rich whole grains, fruits, and dairy products.

  12. Status report on performance of radioisotope thermoelectric generators using silicon germanium thermoelectric elements

    International Nuclear Information System (INIS)

    Bennett, G.L.; Campbell, R.W.; Putnam, L.R.; Hemler, R.J.

    1994-01-01

    Three general-purpose heat source radioisotope thermoelectric generators (GPHS-RTGs) are currently in use in space: two on board the Galileo spacecraft on its way to Jupiter and one on the Ulysses spacecraft exploring the polar regions of the Sun. The GPHS-RTG was designed to provide at least 285 W(e) at the beginning of mission (BOM) within a mass constraint of 56 kg and an overall size envelope of 42.2 cm in diameter and 114 cm in length. The Galileo spacecraft, which as already sent back exciting scientific information on Venus, Earth, and the asteroids Gaspra and Ida, carries two GPHS-RTGs which operate at 30 V. The Ulysses spacecraft, which has already successfully swung past Jupiter on its way to the southern polar regions of the Sun, carries one GPHS-RTG which operates at 28 V. The analyses presented in the paper show that both Galileo and Ulysses will have sufficient power for the baseline missions and analyses are under way to determine the power available for an extended Ulysses mission out to the year 2002. Ten other silicon-germanium-based RTGs on the LES 8/9 and Voyager 1/2 spacecraft have completed their prime missions and are now successfully performing extended missions

  13. Equipment performance and radiation protection status in X-ray fluoroscopy units in Sudan

    International Nuclear Information System (INIS)

    Ahmed, N. A.; Nayl, A. I.; Suliman, I. I.

    2012-01-01

    The number of fluoroscopy and fluoroscopically guided procedures has been substantially growing in developing countries at the same time advanced and sophisticated equipment are used in some hospitals. However, radiation protection requirements are not necessarily well adopted. In this study nine fluoroscopy X-ray units in Sudan were examined for compliance with international standards. The tests included: beam quality, entrance surface air kerma, image quality and radiation field measurements. Staff radiation protection tools such as lead aprons and eye glasses were also visually examined to find out whether international recommendations were fulfilled and to determine the level of staff awareness. The measured peak tube voltage deviation exceeded the recommended tolerance level in 30 % of the measurements. The results of patient doses measurements exceeded the recommended reference dose levels in 43 % of the measurements; however image quality and radiation field generally fulfilled the requirements for most units. The study revealed that a considerable number of fluoroscopy units were not performing according to the international standards and highlights the need of optimisation of radiation protection. (authors)

  14. Status and performance of the CMS muon system in Run2

    CERN Document Server

    Cabrera Mora, Andres Leonardo

    2016-01-01

    The CMS muon system has played a key role for many physics results obtained from the LHC Run1 and Run2 data. During the Long Shutdown (2013-2014), as well as during the last year-end technical stop (2015-2016), significant consolidation and upgrades have been carried out on the muon detectors and on the Level-1 (L1) muon trigger. The algorithms for muon reconstruction and identification have also been improved for both the High-Level Trigger (HLT) and the offline reconstruction. Results of the performance of muon detectors, reconstruction and trigger, obtained using data collected at 13 TeV center-of-mass energy during the 2015 and 2016 LHC runs, are presented. Comparison of simulation with experimental data is also discussed where relevant. The system's state of the art is also shown, as well the improvements foreseen to achieve excellent overall quality of muon reconstruction in the high-luminosity conditions expected during Run2.

  15. The Effect of Sensory Room Intervention on Perceptual-Cognitive Performance and Psychiatric Status of People with Schizophrenia

    Directory of Open Access Journals (Sweden)

    Ara Shahgholi

    2012-10-01

    Full Text Available Objectives: Individuals with schizophrenia show perceptual-cognitive abnormalities. Besides, depression and anxiety is an integral part of the disease most of the times. People with mental diseases, while under institutional care, experience lack of control and choice in their daily lives. Sensory room is an environment in which individuals can choose, control and explore the stimuli around them. So, they can organize their responses to their environment and restore and develop their skills, interacting through it. Methods: 48 people met the study criteria, who were evaluated with Lowenstein Occupational Therapy Cognitive Assessment, Mini Mental State examination, and Positive and Negative Syndrome Scale. Then they were randomly and equally assigned to intervention and comparison groups. Intervention group received sensory room intervention and comparison group had their traditional therapies. After 32 treatment sessions, 14 participants in intervention group and 7 participants in comparison group were excluded from the study and the tests were repeated for the remaining ones. Results: Findings did not show a significant effect of sensory room intervention on perceptual-cognitive performance and psychiatric status of people with schizophrenia (P>0.05. In reminding domain, however, results indicated maintenance of the skill in intervention group (P>0.05. and exacerbating of that in comparison group (P<0.05. Discussion: No significant change in perceptual-cognitive performance and psychiatric status for individuals with schizophrenia during 3 month period of sensory room intervention was found, except for reminding which did not changed significantly in intervention group, but regressed in comparison group after the intervention period.

  16. FY2017 status report: Model 9975 O-ring fixture long-term leak performance

    Energy Technology Data Exchange (ETDEWEB)

    Daugherty, W. L. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-07-27

    A series of experiments to monitor the aging performance of Viton® GLT and GLT-S O-rings used in the Model 9975 shipping package has been ongoing since 2004 at the Savannah River National Laboratory. One approach has been to periodically evaluate the leak performance of O-rings being aged in mock-up 9975 Primary Containment Vessels (PCVs) at elevated temperature. Other methods such as compression-stress relaxation (CSR) tests and field surveillance are also on-going to evaluate O-ring behavior. Seventy tests using PCV mock-ups with GLT O-rings were assembled and heated to temperatures ranging from 200 to 450 ºF. They were leak-tested initially and have been tested periodically to determine if they continue to meet the leak-tightness criterion defined in ANSI standard N14.5-97. Due to material substitution, a smaller test matrix with fourteen additional tests was initiated in 2008 with GLT-S O-rings heated to temperatures ranging from 200 to 400 ºF. Leak test failures have been experienced in all of the GLT O-ring fixtures aging at 350 ºF and higher temperatures, and in 8 fixtures aging at 300 ºF. The 300 °F GLT O-ring fixtures failed after 2.8 to 5.7 years at temperature. The remaining GLT O-ring fixtures aging at 300 ºF were retired from testing following more than 5 years at temperature without failure. No failures have yet been observed in GLT O-ring fixtures aging at 200 ºF for 9 to 10.5 years, or in GLT O-ring fixtures aging at 270 ºF for 5.7 years. These aging temperatures bound O-ring temperatures anticipated during normal storage in K-Area Complex (KAC). Leak test failures have been experienced in all of the GLT-S O-ring fixtures aging at 300 ºF and above. No failures have yet been observed in GLT-S O-ring fixtures aging at 200 and 250 ºF for 6.9 to 7.5 years. Data from the O-ring fixtures are generally consistent with results from compression stress relaxation testing, and provide confidence in the predictive models based on those results

  17. Artificial insemination of cattle in Sri Lanka: Status, performance and problems

    International Nuclear Information System (INIS)

    Abeygunawardena, H.; Alexander, P.A.B.D.; Abeygunawardena, I.S.

    2001-01-01

    Artificial insemination (AI) has been accepted as the primary breeding tool in genetic upgrading programmes of cattle in Sri Lanka. Three studies were conducted, to determine the coverage and performance of AI at national, provincial and district levels (Study 1), the success rate and factors affecting success rate of AI in wet zone mid-country smallholder farms (Study 2) and in wet zone up-country large multiplier farms (Study 3). The objective was to design, implement remedial measures and/or determine future studies necessary to improve the efficiency of AI services. Study 1 revealed that at national level the AI service reached less than 15% of the breedable cattle and accounted for less than 6% of estimated annual calvings. The coverage reached above 50% of the breedable cattle only in the wet zone while in the intermediate and dry zone areas it was negligible. Study 2 revealed that the mean calving to first service interval (CFSI) in cattle of the wet zone mid-country small holdings was 183 ± 87.1 days (n=211) and the calving to conception interval (CCI) was 194 ± 93.9 days (n=143). The first service conception rate (FSCR) was 45% and the overall conception rate (OCR) was 50.2%, with an average of 1.99 services per conception (S/C). Study 3 showed that the mean CFSI and CCI in wet zone upcountry multiplier farmers were 111.2 ± 74.2 days (n=133) and 156 ± 92.7 days (n=170) respectively. The average FSCR and OCR were 50.4% and 53.6% respectively and the average S/C was 1.9. Study 1 showed that the AI coverage of the island is very low and the proportion of calvings from AI is too low to have a significant impact on genetic composition of the national cow population. Studies 2 and 3 showed that the success rate of the AI service in the more favourable and extensively covered wet zone areas was also low. These studies revealed that factors associated with the chain of events from farmer, cow, semen to the technician contributed to poor fertility. (author)

  18. The SEIS Experiment for the InSight mission: status and performance expectations

    Science.gov (United States)

    Mimoun, David; Lognonne, Philippe; Banerdt, W. Bruce; Laudet, Philippe; De Raucourt, Sébastien; IJpelaan, Frans; Kerjean, Laurent; Perez, Rene; Pont, Gabriel; Sylvestre-Baron, Annick; verdier, Nicolas; Denise, Robert; Feldman, Jason; Hurst, Ken; Klein, Kerry; Giardini, Domenico; Zweifel, Peter; Pike, W. Tom; Calcutt, Simon; Bramanti, Christina

    2015-04-01

    discussion will be presented, on how to understand the seismometer performance figure in a changing environment, and how to secure the mission science goals in the challenging environment of the Mars surface.

  19. Nutritional Status and Performance in Test of Verbal and Non-Verbal Intelligence in 6-Year- Old Children

    Science.gov (United States)

    Arija, Victoria; Esparo, Griselda; Fernandez-Ballart, Joan; Murphy, Michelle M.; Biarnes, Elisabeth; Canals, Josefa

    2006-01-01

    The relationship between nutritional status and intellectual capacity in 6-year-old children was investigated in 83 subjects of medium-high socio-economic status, without any apparent risk of malnutrition and normal or high intellectual capacity. Nutritional status was evaluated by measuring food consumption, anthropometrical measurements and…

  20. Biomonitoring of physiological status and cognitive performance of underway submariners undergoing a novel watch-standing schedule

    Science.gov (United States)

    Duplessis, C. A.; Cullum, M. E.; Crepeau, L. J.

    2005-05-01

    Submarine watch-standers adhere to a 6 hour-on, 12 hour-off (6/12) watch-standing schedule, yoking them to an 18-hr day, engendering circadian desynchronization and chronic sleep deprivation. Moreover, the chronic social crowding, shift work, and confinement of submarine life provide additional stressors known to correlate with elevated secretory immunoglobulin A (sIgA) and cortisol levels, reduced performance, immunologic dysfunction, malignancies, infections, gastrointestinal illness, coronary disease, anxiety, and depression. We evaluated an alternative, compressed, fixed work schedule designed to enhance circadian rhythm entrainment, sleep hygiene, performance, and health on 10 underway submariners, who followed the alternative and 6/12 schedules for approximately 2 weeks each. We measured subjects" sleep, cognitive performance, and salivary biomarker levels. Pilot analysis of the salivary data on one subject utilizing ELISA suggests elevated biomarker levels of stress. Average PM cortisol levels were 0.2 μg/L (normal range: nondetectable - 0.15 μg/L), and mean sIgA levels were 562 μg/ml (normal range: 100-500 μg/ml). Future research exploiting real-time salivary bioassays, via fluorescent polarimetry technology, identified by the Office of Naval Research (ONR) as a future Naval requirement, allows researchers to address correlations between stress-induced elaboration of salivary biomarkers with physiological and performance decrements, thereby fostering insight into the underway submariner"s psychoimmunological status. This may help identify strategies that enhance resilience to stressors. Specifically, empirically-based modeling can identify optimal watch-standing schedules and stress-mitigating procedures -- within the operational constraints of the submarine milieu and the mission --that foster improved circadian entrainment and reduced stress reactivity, enhancing physiological health, operational performance, safety, and job satisfaction.

  1. Employment status of patients receiving maintenance dialysis – peritoneal and hemodialysis: A cross-sectional study

    Directory of Open Access Journals (Sweden)

    B S Lakshmi

    2017-01-01

    Full Text Available The long-term dialysis therapy for end-stage renal disease takes a heavy toll of quality of life of the patient. Several factors such as fatigue and decreased physical capability, impaired social and mental functioning, contribute to this forlorn state. To meld maintenance dialysis treatment with a regular employment can be a serious test. A cross-sectional study of employment of patients on hemodialysis and peritoneal dialysis in a state government tertiary institute in South India was performed between June 2015 and December 2015. Patients who completed 3 months of regular dialysis were only included in the study. The number of patients on hemodialysis was 157 and on peritoneal dialysis was 69. The employment status before the initiation of dialysis was 60% (93 out of 155 and 63.7% (44 out of 69 in hemodialysis and peritoneal dialysis, respectively. After initiation, the loss of employment was observed in 44% (41 out of 93 in hemodialysis and 51.2% (26 out of 44 in peritoneal dialysis (P = 0.2604. Even though there was fall of absolute number of job holders in both the blue and white collar jobs, the proportion of jobholders in the white collar job holders improved. On univariate analysis, the factors which influenced the loss of employment were males, age between 50 and 60 years, number of comorbidities >2, illiteracy and blue collar versus white collar job before the initiation of dialysis. The majority of patients had the scores above 80 on Karnofsky performance scale and the majority belonged upper and middle classes than lower classes on modified Kuppuswamy's socioeconomic status scale; however, the loss of employment was also disproportionately high. There appeared a substantial difference in the attitude of the patients toward the employment. There was no difference between hemodialysis and peritoneal dialysis in the loss of employment of our patients.

  2. Survival of patients with head and neck cancer. Impact of physical status and comorbidities.

    Science.gov (United States)

    Sadat, F; Wienke, A; Dunst, J; Kuhnt, T

    2012-01-01

    Prognostic factors (e.g., gender, tumor stage, and hypoxia) have an impact on survival in patients with head and neck cancer. Thus, the impact of physical status and comorbidities on treatment decision and survival were evaluated. A total of 169 primary, inoperable patients with squamous cell cancer of the head and neck were retrospectively investigated. Patients were treated with hyperfractionated accelerated radio(chemo)therapy (HARcT) or hypofractionated radio(chemo)therapy (HypoRcT). Depending on the individual patient's situation (Karnofsky Performance Index, KPI), treatment for patients with a KPI of 80-100% was generally radiochemotherapy and for patients with a KPI ≤ 70% treatment was radiotherapy alone. In addition, all comorbidities were evaluated. Uni- and multivariate proportional hazards model were used, and overall survival (OS) was estimated by the Kaplan-Meier method. Treatment consisted of HARcT for 76 patients (45%), HART for 28 patients (17%), HypoRcT for 14 patients(8%), and HypoRT for 51 patients (30%). Of the patients, 107 patients (63%) presented with a KPI of 80-100%. OS (20%) was significantly better for patients with a KPI of 80-100%, while the OS for patients with a KPI ≤ 70% was 8% (p KPI, total irradiation dose (> 70 Gy), and chemotherapy were significant prognostic factors for better OS. Our retrospective analysis shows that performance status with dependency on comorbidities was an independent risk factor for OS.

  3. Differences in mathematics and science performance by economic status, gender, and ethnicity/race: A multiyear Texas statewide study

    Science.gov (United States)

    Anderson, Pamela Bennett

    Purpose. The purpose of the first study was to ascertain the extent to which differences were present in the STAAR Mathematics and Science test scores by Grade 5 and Grade 8 student economic status. The purpose of the second study was to examine differences in Grade 5 STAAR Mathematics and Science test performance by gender and by ethnicity/race (i.e., Asian, Black, Hispanic, and White). Finally, with respect to the third study in this journal-ready dissertation, the purpose was to investigate the STAAR Mathematics and Science test scores of Grade 8 students by gender and by ethnicity/race (i.e., Asian, Black, Hispanic, and White). Method. For this journal-ready dissertation, a non-experimental, causal-comparative research design (Creswell, 2009) was used in all three studies. Grade 5 and Grade 8 STAAR Mathematics and Science test data were analyzed for the 2011-2012 through the 2014-2015 school years. The dependent variables were the STAAR Mathematics and Science test scores for Grade 5 and Grade 8. The independent variables analyzed in these studies were student economic status, gender, and ethnicity/race. Findings. Regarding the first study, statistically significant differences were present in Grade 5 and Grade 8 STAAR Mathematics and Science test scores by student economic status for each year. Moderate effect sizes (Cohen's d) were present for each year of the study for the Grade 5 STAAR Mathematics and Science exams, Grade 8 Science exams, and the 2014-2015 Grade 8 STAAR Mathematics exam. However, a small effect size was present for the 2011-2012 through 2013-2014 Grade 8 STAAR Mathematics exam. Regarding the second and third study, statistically significant differences were revealed for Grade 5 and Grade 8 STAAR Mathematics and Science test scores based on gender, with trivial effect sizes. Furthermore, statistically significant differences were present in these test scores by ethnicity/race, with moderate effects for each year of the study. With regard to

  4. The age-gender-status profile of high performing athletes in the UK taking nutritional supplements: Lessons for the future

    Directory of Open Access Journals (Sweden)

    Naughton Declan P

    2008-01-01

    Full Text Available Abstract Background Owing to the mechanics of anti-doping regulation via the World Anti-Doping Agency's Prohibited List, nutritional supplement use received little attention in comparison to the prevalence of doping. The aims of this study were to investigate supplement use, identify groups of athletes with high levels of supplement use and the prevalence of concomitant use of supplements. Methods Survey data from 847 high-performing athletes in the UK were analysed using descriptive statistics. The survey, conducted by UK Sport, consisted of questions regarding knowledge of the prohibited substances, testing procedure, nutritional supplement use and perceptions of the doping problem. The proportion of supplement users and the relative use of each supplement were compared by age, gender and professional status. Results Among 874 high-performing athletes in the UK sample, 58.8% of them reported the use of at least one nutritional supplement. Among supplement users, 82.6% used more than one and 11.5% reported use of more than five nutritional supplements. Of the 9 supplements listed, multivitamins (72.6% and vitamin C (70.7% were used most, followed by creatine (36.1%, whey protein (31.7%, echinacea (30.9%, iron (29.9% and caffeine (23.7%. Less than 11% reported the use of magnesium or ginseng. Creatine use was typically associated with males regardless of status and across all ages, whereas iron was characteristically used by females. A 'typical' supplement user is male, between 24 and 29 years of age, involved in professional sport and using a combination of supplements. Male professional players between age 30 and 34 years, and female non-professional athletes between 24 and 29 years of age also represented a considerable proportion of supplement users. Athletes older than 40 years of age were practically non-users. Concomitant use of supplements is characteristic of male users more than females. Conclusion As supplement use has been previously

  5. Undernutrition, fatty acid and micronutrient status in relation to cognitive performance in Indian school children: a cross-sectional study.

    Science.gov (United States)

    Eilander, Ans; Muthayya, Sumithra; van der Knaap, Henk; Srinivasan, Krishnamachari; Thomas, Tinku; Kok, Frans J; Kurpad, Anura V; Osendarp, Saskia J M

    2010-04-01

    While undernutrition and anaemia have previously been linked to poor development of children, relatively little is known about the role of B-vitamins and fatty acids on cognition. The present study aims to explore the associations between indicators of body size, fatty acid and micronutrient status on cognitive performance in 598 Indian school children aged 6-10 years. Baseline data of a clinical study were used to assess these associations by analyses of variance adjusting for age, sex, school, maternal education and cognitive tester. The Kaufman Assessment Battery for Children II was used to measure four cognitive domains, including fluid reasoning, short-term memory, retrieval ability and cognitive speediness. Scores were combined into an overall measure, named mental processing index (MPI). Body size indicators and Hb concentrations were significantly positively related to cognitive domains and MPI, such that increases of 1 sd in height-for-age and weight-for-age z-scores would each translate into a 0.09 sd increase in MPI, P = 0.0006 and 0.002, respectively. A 10 g/l increase in Hb concentrations would translate into a 0.08 sd increase in MPI, P = 0.0008. Log-transformed vitamin B12 concentrations were significantly inversely associated with short-term memory, retrieval ability and MPI (beta (95 % CI) = - 0.124 (- 0.224, - 0.023), P = 0.02). Other indicators of Fe, iodine, folate and fatty acid status were not significantly related to cognition. Our findings for body size, fatty acids and micronutrients were in agreement with previous observational studies. The inverse association of vitamin B12 with mental development was unexpected and needed further study.

  6. Physical fitness as an indicator of health status and its relationship to academic performance during the prepubertal period.

    Science.gov (United States)

    Fonseca Del Pozo, Francisco Javier; Alonso, Joaquín Valle; Álvarez, Manuel Vaquero; Orr, Siobhan; Cantarero, Francisco Jesús Llorente

    2017-01-01

    Background: Physical activity (PA) is considered one of the most important determinants of the health status in children, and predictor of morbidity/mortality in adults. The aim is to examine the relationship between physical fitness (PF), PA, obesity and academic performance (AP) in primary school children. Methods: Cross-sectional studies including 91 primary school students, aged 9 to 12 years, from the province of Córdoba. Data was collected from April to June 2014. We measured PF using part of the EUROFIT fitness testing battery. The level of PA was measured as low or high PF and the level of obesity was measured using body mass index, waist circumference, percentage of fat mass, lean body mass, percentage of lean mass and basal metabolism. AP by scores on the second quarter was based on the total average of scores of basic subjects and other subjects, including physical education. Cognitive performance was assessed by the Spanish overall and factorial intelligence test. Results: The results of AP were positively related to levels of PF. Students who achieve better PF score better in Maths, (P=0.019), Natural Sciences (P=0.024), Religion (P=0.018) and Physical Education (Plevels of fitness. Therefore, the education system should consider implementing curriculum strategies favouring the improvement of the PF, and therefore the health and AP of students.

  7. Sedentary behavior during school-time: Sociodemographic, weight status, physical education class, and school performance correlates in Brazilian schoolchildren.

    Science.gov (United States)

    da Costa, Bruno G G; da Silva, Kelly S; George, Amanda M; de Assis, Maria Alice A

    2017-01-01

    To investigate whether sedentary behavior during school-time is associated with gender, age, mother's education, having physical education classes, weight status, and academic performance. Cross-sectional study. A sample of 571 children (7-12 years old) from five elementary schools in Florianopolis, South Brazil had their height and weight measured, and wore accelerometers during class time. Teachers completed a form to evaluate children's reading and writing skills. Parents provided sociodemographic and educational information. Data was analyzed using multilevel linear regression analyses. Children spent an average of 132min in sedentary behavior during school-time (64% of total school-time). Girls (137.5min), obese children (138.1min), older children (144.2min), and those who did not have physical education classes (140.2min) spent more time engaged in sedentary activities than their peers. Academic performance and mother's education were not associated with sedentary behaviors. Children spent most of their school-time in sedentary activities, with girls, older students, and obese students being even more sedentary than their peers. Physical education classes were a protective factor against excessive sedentary behavior in school. Interventions for reducing sedentary behavior during school-time could employ additional strategies to benefit the at risk groups. In addition, encouraging student's participation in physical education classes could minimize the time spent in sedentary behavior during school hours. Copyright © 2016 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  8. Physical fitness as an indicator of health status and its relationship to academic performance during the prepubertal period

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    Francisco Javier Fonseca del Pozo

    2017-09-01

    Full Text Available Background: Physical activity (PA is considered one of the most important determinants of the health status in children, and predictor of morbidity/mortality in adults. The aim is to examine the relationship between physical fitness (PF, PA, obesity and academic performance (AP in primary school children Methods: Cross-sectional studies including 91 primary school students, aged 9 to 12 years, from the province of Córdoba. Data was collected from April to June 2014. We measured PF using part of the EUROFIT fitness testing battery. The level of PA was measured as low or high PF and the level of obesity was measured using body mass index, waist circumference, percentage offal mass, lean body mass, percentage of lean mass and basal metabolism. AP by scores on the second quarter was based on the total average of scores of basic subjects and other subjects, including physical education. Cognitive performance was assessed by the Spanish overall and factorial intelligence test.Results: The results of AP were positively related to levels of PF. Students who achieve better PF score better in Maths, (P=0.019, Natural Sciences (P=0.024, Religion (P=0.018 and Physical Education (P<0.001. A direct association between maximal aerobic capacity with Mathematics (r=0.325, P=0.02, AP (r=0.349, P=0.001 and cognitive performance (CP(r=0.312, P=0.003 was observed. There was also a direct association of better jump tests with higher AP (r=0.328, P=0.002.Conclusion: The AP is associated with higher levels of fitness. Therefore, the education system should consider implementing curriculum strategies favouring the improvement of the PF, and therefore the health and AP of students.

  9. Prevalence of upper gastrointestinal symptoms and their influence on nutritional state and performance status in patients with different primary tumors receiving palliative care.

    Science.gov (United States)

    Bovio, Giacomo; Fonte, Maria Luisa; Baiardi, Paola

    2014-02-01

    The aim of this study was to investigate the relationship between gastrointestinal symptoms, nutritional balance, and performance status in patients receiving palliative care for advanced cancers originating in different sites. We studied a total of 105 patients. Upper gastrointestinal symptoms, Eastern Cooperative Oncology Group Performance Status score (ECOG-PS), dietary intakes, anthropometric measures, and some serum proteins were determined. Unintentional weight loss, alterations in anthropometric measures, and highest number of symptoms were greater in patients with lung and stomach cancer. No differences were found in ECOG-PS according to cancer site. Patients with gastric or lung cancer have most evidence of protein-calorie malnutrition and a higher prevalence of upper gastrointestinal symptoms. The performance status is not affected by tumor site. Early nutritional support should be planned for all patients with cancer, especially for patients with gastric or lung cancer.

  10. Effect of 12-Week Vitamin D Supplementation on 25[OH]D Status and Performance in Athletes with a Spinal Cord Injury

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    Joelle Leonie Flueck

    2016-09-01

    Full Text Available (1 Background: studies with able-bodied athletes showed that performance might possibly be influenced by vitamin D status. Vitamin D seems to have a direct impact on neuromuscular function by docking on vitamin D receptors in the muscle tissue. Additionally, a high prevalence of vitamin D deficiency was shown not only in infants and in the elderly but also in healthy adults and spinal cord injured individuals. Therefore, the aim of our study was to investigate whether a vitamin D dose of 6000 IU daily over 12 weeks would be sufficient to increase vitamin D status in indoor wheelchair athletes to a normal or optimal vitamin D level and whether vitamin D deficiency is associated with an impairment in muscle performance in these individuals; (2 Methods: vitamin D status was assessed in indoor elite wheelchair athletes in order to have a baseline measurement. If vitamin D status was below 75 nmol/L, athletes were supplemented with 6000 IU of vitamin D daily over 12 weeks. A vitamin D status over 75 nmol/L was supplemented with a placebo supplement. Vitamin D status, as well as a Wingate test and an isokinetic dynamometer test, were performed at baseline and after six and 12 weeks; (3 Results: 20 indoor elite wheelchair athletes participated in this double-blind study. All of these athletes showed an insufficient vitamin D status at baseline and were, therefore, supplemented with vitamin D. All athletes increased vitamin D status significantly over 12 weeks and reached an optimal level. Wingate performance was not significantly increased. Isokinetic dynamometer strength was significantly increased but only in the non-dominant arm in isometric and concentric elbow flexion; (4 Conclusion: a dose of 6000 IU of vitamin D daily over a duration of 12 weeks seems to be sufficient to increase vitamin D status to an optimal level in indoor wheelchair athletes. It remains unclear, whether upper body performance or muscle strength and vitamin D status are

  11. STATUS KESEHATAN GIGI, PERFORMED TREATMENT INDEX DAN REQUIRED TREATMENT INDEX ANAK SEKOLAH DASAR DI KABUPATEN CIANJUR, KARAWANG DAN SERANG

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    Magdarina D. Agtini

    2012-10-01

    Full Text Available Community dental health status for permanent teeth in determined by the DMF-T (Decayed Misssing and Filled Teeth. The DMF-T in a number of industrialized nations shows a tendency to drop while the trend in developing nations is increasing. In Indonesia dental caries is still the foremost problem in oral and dental diseases, Prevalence of dental caries is around 85%-99%. The DMF-T is varied, reflect geographic and ages variations. In three decade's the intensity of dental caries is increasing with each decade, 0,70 DMF-T in 1970 to be 2,30 DMF-T in 1980 and 2,70 DMF-Tin 1990. Goal of dental caries control for 2010 is DMF-T ≤ 1 for 12 years age group. Baseline study is therefore necessary to ascertain DMF-T, PTI (Performed Treatment Index and RTI (Required Treatment Index. The study was implemented in the districts of Cianjur, Karawang and Serang in West Java for two years. The study design was cohort. The respondents  were 1200 pupils aged 8 years, randomly selected with a signifzcantcy grade of p < 0,05 and power of 0,20. The study results showed average of DMF-T at the beginning was 1,52 ± 1,21, and after two years the DMF-T was 2.45 ± 1.51 comprise only of the decayed component, and There was significant different (p=0,000. The DMF-T was low WHO criteria, nevertheless the PTI (1,2% was very low and the RTI (98% was very high. The DMF_T average shows a tendency to increase, with D as the largest component and F (Filling the smallest one. The control of dental caries faces several problems, like the limited number of manpower and facilities, and limited supply of water and electricity incertain areas. Therefore treatment of dental caries with GIC fillings using the ART method should be taken into consideration receive the necessary attention.   Key words:  Status kesehatan gigi, Karies, Performed treatment Index (PTI,  Required Treatment  Index (RTI

  12. Effects of Wine by-Products on Growth Performance, Complete Blood Count and Total Antioxidant Status in Broilers

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    SM Pascariu

    Full Text Available ABSTRACT This study aimed to investigate the effect of whole grape pomace (GP, grape seed (GS and grape pomace polyphenolic extract (GPEP on growth performance, total antioxidant status (TAS and complete blood count (CBC of 40-day-old chicks (hybrid Cobb 500. A total of 432 unsexed one-day-old chicks were divided into six groups: control (CON and five experimental groups, 10 g/kg GP, 20 g/kg GP, 5 g/kg GS, 10 g/kg GS and 15 mL/L GPEP. The results showed a higher increase in growing rate in 5 g/kg GS group, from the first week of the chicks’ life throughout their growth, the average body weight of the chicks being significantly higher (p0.05 at 40 days of age. As a conclusion, the amount of 5 g/kg seeds, 10 g/kg and 20 g/kg pomace, can be added to the diet of the broilers, the dose of 5 g/kg seeds in the diet offering advantages in growing rate and feed valorization in weight gain.

  13. Effect of Cocoa Butter and Sunflower Oil Supplementation on Performance, Immunoglobulin, and Antioxidant Vitamin Status of Rats

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    Ebru Yıldırım

    2014-01-01

    Full Text Available This study investigated the effects of cocoa butter and sunflower oil alone and in combination on performance, some biochemical parameters, immunoglobulin, and antioxidant vitamin status in Wistar rats. Forty-eight male rats were assigned to four groups, consisting of 12 rats with 3 replicates. Control received balanced rat diet without oil, cocoa butter group received 3.5% cocoa butter, sunflower oil group received 3.5% sunflower oil, the last group received 1.75% sunflower oil + 1.75% cocoa butter supplementation in the rat diet for 8 weeks. The total feed consumption in sunflower oil group was statistically lower than in the other groups. The serum creatinine level was decreased in cocoa butter group compared to control. Triglyceride and VLDL cholesterol levels were decreased in only sunflower oil and only cocoa butter groups as compared to control. The level of Ig M was statistically lower in cocoa butter and cocoa butter + sunflower oil groups than in control and sunflower oil groups. There were no statistically important difference in vitamin concentrations among trial groups. It was concluded that the supplementation of cocoa butter in diet decreased Ig M level, while the supplementation of cocoa butter and sunflower oil alone decreased the triglyceride and VLDL cholesterol levels.

  14. Effect of dietary polyunsaturated fatty acids and Vitamin E on serum oxidative status in horses performing very light exercise

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    Liviana Prola

    2010-01-01

    Full Text Available In sporting horses the use of dietary polyunsaturated fatty acids (PUFAs could enhance performance because these fatty acids are very important in membrane permeability, and in particular they seem to increase the possibility of long chain fatty acids entering mythochondria to be burnt. The composition of cellular membranes and lipoprotein fatty acids com- position is strictly related to dietary fat quality; percentages of polyunsaturated fatty acids and amount of antioxidants also affect tissue susceptibility to lipid peroxidation. Six horses were used in a latin square design in which three homogeneous groups were subsequently assigned three dif- ferent dietary treatments for one month each: Control group (C: basic diet; Oil group (O: Basic diet + 200g/day oil rich in PUFAs (Crossential GLA TG20, Croda ®; Vitamin E group (O+E: basic diet + 200 g/day oil rich in PUFAs (Crossential GLA TG20, Croda ® + 5 g/day α-toco- pheryl-acetate (Egon-E, Acme ®. At the end of each experimental period blood samples were taken by jugular vein puncture. Serum oxidative status was evaluated by TBARs and d-ROMs assessment. Oxidative markers showed the high- est mean values for the oil group, even if no statistically significant differences were found.

  15. Effect of immobilization and performance status on intrafraction motion for stereotactic lung radiotherapy: analysis of 133 patients.

    Science.gov (United States)

    Li, Winnie; Purdie, Thomas G; Taremi, Mojgan; Fung, Sharon; Brade, Anthony; Cho, B C John; Hope, Andrew; Sun, Alexander; Jaffray, David A; Bezjak, Andrea; Bissonnette, Jean-Pierre

    2011-12-01

    To assess intrafractional geometric accuracy of lung stereotactic body radiation therapy (SBRT) patients treated with volumetric image guidance. Treatment setup accuracy was analyzed in 133 SBRT patients treated via research ethics board-approved protocols. For each fraction, a localization cone-beam computed tomography (CBCT) scan was acquired for soft-tissue registration to the internal target volume, followed by a couch adjustment for positional discrepancies greater than 3 mm, verified with a second CBCT scan. CBCT scans were also performed at intrafraction and end fraction. Patient positioning data from 2047 CBCT scans were recorded to determine systematic (Σ) and random (σ) uncertainties, as well as planning target volume margins. Data were further stratified and analyzed by immobilization method (evacuated cushion [n=75], evacuated cushion plus abdominal compression [n=33], or chest board [n=25]) and by patients' Eastern Cooperative Oncology Group performance status (PS): 0 (n=31), 1 (n=70), or 2 (n=32). Using CBCT internal target volume was matched within ±3 mm in 16% of all fractions at localization, 89% at verification, 72% during treatment, and 69% after treatment. Planning target volume margins required to encompass residual setup errors after couch corrections (verification CBCT scans) were 4 mm, and they increased to 5 mm with target intrafraction motion (post-treatment CBCT scans). Small differences (position were observed between the immobilization cohorts in the localization, verification, intrafraction, and post-treatment CBCT scans (pPositional drift varied according to patient PS, with the PS 1 and 2 cohorts drifting out of position by mid treatment more than the PS 0 cohort in the cranial-caudal direction (p=0.04). Image guidance ensures high geometric accuracy for lung SBRT irrespective of immobilization method or PS. A 5-mm setup margin suffices to address intrafraction motion. This setup margin may be further reduced by strategies such as

  16. R&D status and the performance of domestic firms in China's coal mining industry

    International Nuclear Information System (INIS)

    Sun, Sizhong; Anwar, Sajid

    2015-01-01

    Coal use accounts for a very large proportion of electricity production in China. Using a recently developed coarsened exact matching (CEM) technique, this paper examines the impact of research and development (R&D) activities on the performance of firms in China's coal mining industry. Our empirical results reveal that firms in China's coal industry that conduct R&D are more productive and their sales are higher. However, as far as the firm profitability and market shares are concerned, whether or not a firm in China's coal industry conducts R&D makes no difference. We find that foreign direct investment in China's coal mining industry leads to a significant decrease in the market share of domestic firms and its impact on productivity, sales and profitability of domestic firms is insignificant. The empirical results presented in this paper suggest that policies that encourage domestic firms in China's coal mining industries to conduct R&D can increase domestic production thereby reducing reliance on imports. Furthermore, productivity gains arising from R&D activities can also help Chinese mining firms to improve their competitive position in the international market. However, there is a need for restricting foreign direct investment in China's coal mining industry. - Highlights: • R&D status affects firm performance in China's coal mining industry. • Coal mining firms that conduct R&D are, on average, 0.2717% more productive. • Coal mining firms that conduct R&D experience an increase in sales. • Increase in foreign investment decreases the market share of coal mining firms

  17. Effects of feeding lutein on production performance, antioxidative status, and milk quality of high-yielding dairy cows.

    Science.gov (United States)

    Xu, C Z; Wang, H F; Yang, J Y; Wang, J H; Duan, Z Y; Wang, C; Liu, J X; Lao, Y

    2014-11-01

    performance and health status of dairy cows. Copyright © 2014 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  18. So Young and Already Victims of Stereotype Threat: Socio-Economic Status and Performance of 6 to 9 Years Old Children on Raven's Progressive Matrices

    Science.gov (United States)

    Desert, Michel; Preaux, Marie; Jund, Robin

    2009-01-01

    The aim of this study was to verify whether children from low socio-economic status (SES) are victims of stereotype threat. Children in first grade (6 to 7 years old) and third grade (8 to 9 years old) performed Raven's progressive matrices, an intellectual ability test commonly used by psychologists. The test was presented either with the…

  19. Parental Socio-Economic Status, Self-Concept and Gender Differences on Students' Academic Performance in Borno State Colleges of Education: Implications for Counselling

    Science.gov (United States)

    Goni, Umar; Bello, S.

    2016-01-01

    This is a survey study, designed to determine gender differences and socio-economic status, self-concept on students' academic performance in Colleges of Education, Borno State: Implications for counselling. The study set two research objectives, answered two research questions and tested two research hypotheses. The target population of this…

  20. Analysis of English language learner performance on the biology Massachusetts comprehensive assessment system: The impact of english proficiency, first language characteristics, and late-entry ELL status

    Science.gov (United States)

    Mitchell, Mary A.

    This study analyzed English language learner (ELL) performance on the June 2012 Biology MCAS, namely on item attributes of domain, cognitive skill, and linguistic complexity. It examined the impact of English proficiency, Latinate first language, first language orthography, and late-entry ELL status. The results indicated that English proficiency was a strong predictor of performance and that ELLs at higher levels of English proficiency overwhelmingly passed. The results further indicated that English proficiency introduced a construct-irrelevant variance on the Biology MCAS and raised validity issues for using this assessment at lower levels of English proficiency. This study also found that ELLs with a Latinate first language consistently had statistically significant lower performance. Late-entry ELL status did not predict Biology MCAS performance.

  1. Impact of early castration and health status on the performance of Holstein-Friesian and beef crossbred calves

    Directory of Open Access Journals (Sweden)

    Wielgosz-Groth Zofia

    2016-06-01

    Full Text Available Introduction: This article presents the analysis of the correlation between the category and health status of calves and the results of their rearing and levels of selected blood parameters.

  2. Anemia and performance status as prognostic markers in acute hypercapnic respiratory failure due to chronic obstructive pulmonary disease

    Directory of Open Access Journals (Sweden)

    Haja Mydin H

    2013-03-01

    Full Text Available Helmy Haja Mydin, Stephen Murphy, Howell Clague, Kishore Sridharan, Ian K TaylorDepartment of Respiratory Medicine, Sunderland Royal Infirmary, Sunderland, United KingdomBackground: In patients with acute hypercapnic respiratory failure (AHRF during exacerbations of COPD, mortality can be high despite noninvasive ventilation (NIV. For some, AHRF is terminal and NIV is inappropriate. However there is no definitive method of identifying patients who are unlikely to survive. The aim of this study was to identify factors associated with inpatient mortality from AHRF with respiratory acidosis due to COPD.Methods: COPD patients presenting with AHRF and who were treated with NIV were studied prospectively. The forced expiratory volume in 1 second (FEV1, World Health Organization performance status (WHO-PS, clinical observations, a composite physiological score (Early Warning Score, routine hematology and biochemistry, and arterial blood gases prior to commencing NIV, were recorded.Results: In total, 65 patients were included for study, 29 males and 36 females, with a mean age of 71 ± 10.5 years. Inpatient mortality in the group was 33.8%. Mortality at 30 days and 12 months after admission were 38.5% and 58.5%, respectively. On univariate analysis, the variables associated with inpatient death were: WHO-PS ≥ 3, long-term oxygen therapy, anemia, diastolic blood pressure < 70 mmHg, Early Warning Score ≥ 3, severe acidosis (pH < 7.20, and serum albumin < 35 g/L. On multivariate analysis, only anemia and WHO-PS ≥ 3 were significant. The presence of both predicted 68% of inpatient deaths, with a specificity of 98%.Conclusion: WHO-PS ≥ 3 and anemia are prognostic factors in AHRF with respiratory acidosis due to COPD. A combination of the two provides a simple method of identifying patients unlikely to benefit from NIV.Keywords: acute exacerbations of COPD, noninvasive ventilation, emphysema, prognostic markers

  3. Feeding time can alleviate negative effects of heat stress on performance, meat quality and health status of turkey.

    Science.gov (United States)

    Farghly, M F A; Alagawany, M; Abd El-Hack, M E

    2018-04-01

    1. A total of 180 one-day-old turkeys were randomly assigned to 6 equal groups to investigate the effect of feeding time on growth performance, carcass characteristics, meat quality, leg problems and physiological responses of growing turkeys under the high temperature conditions of summer. 2. Birds of the first group were ad libitum fed and were considered as the controls (C). The second group (T1) was given 80% of diet in the morning and 20% of diet in the afternoon, the third group (T2) was given 60% of diet in the morning and 40% of diet in the afternoon, the fourth group (T3) was given 40% of diet in the morning and 60% of diet in the afternoon, the fifth group (T4) was given 20% of diet in the morning and 80% of diet in the afternoon and the sixth group (T5) was given 100% of diet in the afternoon. 3. Body weight, body weight gain and feed conversion ratio were improved with T2, T3, T4 and T5 in comparison to control or T1 under heat stress conditions. No significant impacts on carcass traits and meat quality due to changing the time of feeding were seen, except for tenderness and juiciness. 4. Feeding in the afternoon (100%) decreased body temperature and tonic immobility test score, which were positively related with the health condition of the birds. 5. The incidence of leg problems, plumage condition and breast blisters were not significantly different among the experimental groups. 6. It is concluded that feeding turkeys mainly or totally in the afternoon (T4 and T5, birds were fed with 80% or 100% of the diet in the afternoon) can be used as a strategy and a managerial tool for improving growth rate, feed utilisation, carcass and meat quality, as well as health status of growing turkeys reared under hot climate conditions.

  4. Quality of Life in Patients With Advanced Cancer: Differential Association With Performance Status and Systemic Inflammatory Response.

    Science.gov (United States)

    Laird, Barry J A; Fallon, Marie; Hjermstad, Marianne J; Tuck, Sharon; Kaasa, Stein; Klepstad, Pål; McMillan, Donald C

    2016-08-10

    Quality of life is a key component of cancer care; however, the factors that determine quality of life are not well understood. The aim of this study was to examine the relationship between quality of life parameters, performance status (PS), and the systemic inflammatory response in patients with advanced cancer. An international biobank of patients with advanced cancer was analyzed. Quality of life was assessed at a single time point by using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire C-30 (EORTC QLQ-C30). PS was assessed by using the Eastern Cooperative Oncology Group (ECOG) classification. Systemic inflammation was assessed by using the modified Glasgow Prognostic Score (mGPS), which combines C-reactive protein and albumin. The relationship between quality of life parameters, ECOG PS, and the mGPS was examined. Data were available for 2,520 patients, and the most common cancers were GI (585 patients [22.2%]) and pulmonary (443 patients [17.6%]). The median survival was 4.25 months (interquartile range, 1.36 to 12.9 months). Increasing mGPS (systemic inflammation) and deteriorating PS were associated with deterioration in quality-of-life parameters (P quality-of-life parameters independent of PS. Systemic inflammation was associated with quality-of-life parameters independent of PS in patients with advanced cancer. Further investigation of these relationships in longitudinal studies and investigations of possible effects of attenuating systemic inflammation are now warranted. © 2016 by American Society of Clinical Oncology.

  5. Effect of Immobilization and Performance Status on Intrafraction Motion for Stereotactic Lung Radiotherapy: Analysis of 133 Patients

    International Nuclear Information System (INIS)

    Li, Winnie; Purdie, Thomas G.; Taremi, Mojgan; Fung, Sharon; Brade, Anthony; Cho, B.C. John; Hope, Andrew; Sun, Alexander; Jaffray, David A.; Bezjak, Andrea; Bissonnette, Jean-Pierre

    2011-01-01

    Purpose: To assess intrafractional geometric accuracy of lung stereotactic body radiation therapy (SBRT) patients treated with volumetric image guidance. Methods and Materials: Treatment setup accuracy was analyzed in 133 SBRT patients treated via research ethics board–approved protocols. For each fraction, a localization cone-beam computed tomography (CBCT) scan was acquired for soft-tissue registration to the internal target volume, followed by a couch adjustment for positional discrepancies greater than 3 mm, verified with a second CBCT scan. CBCT scans were also performed at intrafraction and end fraction. Patient positioning data from 2047 CBCT scans were recorded to determine systematic (Σ) and random (σ) uncertainties, as well as planning target volume margins. Data were further stratified and analyzed by immobilization method (evacuated cushion [n = 75], evacuated cushion plus abdominal compression [n = 33], or chest board [n = 25]) and by patients’ Eastern Cooperative Oncology Group performance status (PS): 0 (n = 31), 1 (n = 70), or 2 (n = 32). Results: Using CBCT internal target volume was matched within ±3 mm in 16% of all fractions at localization, 89% at verification, 72% during treatment, and 69% after treatment. Planning target volume margins required to encompass residual setup errors after couch corrections (verification CBCT scans) were 4 mm, and they increased to 5 mm with target intrafraction motion (post-treatment CBCT scans). Small differences (<1 mm) in the cranial–caudal direction of target position were observed between the immobilization cohorts in the localization, verification, intrafraction, and post-treatment CBCT scans (p < 0.01). Positional drift varied according to patient PS, with the PS 1 and 2 cohorts drifting out of position by mid treatment more than the PS 0 cohort in the cranial-caudal direction (p = 0.04). Conclusions: Image guidance ensures high geometric accuracy for lung SBRT irrespective of immobilization

  6. Relationship between the degree of insulin resistance during late gestation and postpartum performance in dairy cows and factors that affect growth and metabolic status of their calves.

    Science.gov (United States)

    Kawashima, Chiho; Munakata, Megumi; Shimizu, Takashi; Miyamoto, Akio; Kida, Katsuya; Matsui, Motozumi

    2016-06-01

    This study aimed to investigate the effects of insulin resistance (IR) during the close-up dry period on the metabolic status and performance of dairy cows as well as to determine the effects on body weight (BW) and metabolic status of their calves. An insulin tolerance test (ITT) was conducted by administering 0.05 IU/kg BW of insulin to 34 multiparous Holstein cows at 3 weeks prepartum. Blood samples were collected at 0, 30, 45 and 60 min after insulin injection, and cows were divided into two groups based on the time required for glucose to reach the minimum levels [non-IR (NIR), 45 min (n=28); and IR, 60 min (n=6)]. Blood or milk sampling and body condition score (BCS) estimation were performed twice weekly during the experimental period. Blood samples from calves were collected immediately after birth. Cows with IR showed lower BCS (Pinsulin-like growth factor-I concentration (Pinsulin concentration (Pdairy cows is related to postpartum metabolic status and performance along with growth and metabolic status of their calves.

  7. Delirium in advanced age and dementia: A prolonged refractory course of delirium and lower functional status

    Science.gov (United States)

    BOETTGER, SOENKE; JENEWEIN, JOSEF; BREITBART, WILLIAM

    2017-01-01

    Objective The factors associated with persistent delirium, in contrast to resolved delirium, have not been studied well. The aim of our present study was to identify the factors associated with delirium resolution as measured by the Memorial Delirium Assessment Scale (MDAS) and functional improvement as measured by the Karnofsky Performance Status (KPS) scale. Method All subjects were recruited from psychiatric referrals at the Memorial Sloan Kettering Cancer Center (MSKCC). The two study instruments were performed at baseline (T1), at 2–3 days (T2), and at 4–7 days (T3). Subjects with persistent delirium were compared to those with resolved delirium in respect to sociodemographic and medical variables. Results Overall, 26 out of 111 patients had persistent delirium. These patients were older, predominantly male, and had more frequently preexisting comorbid dementia. Among cancer diagnoses and stage of illness, brain cancer and terminal illness contributed to persistent delirium or late response, whereas gastrointestinal cancer was associated with resolved delirium. Among etiologies, infection responded late to delirium management, usually at one week. Furthermore, delirium was more severe in patients with persistent delirium from baseline through one week. At baseline, MDAS scores were 20.1 in persistent delirium compared to 17 to 18.8 in resolved delirium (T2 and T3), and at one week of management (T3), MDAS scores were 15.2 and 4.7 to 7.4, respectively. At one week of management, persistent delirium manifested in more severe impairment in the domains of consciousness, cognition, organization, perception, psychomotor behavior, and sleep–wake cycle. In addition, persistent delirium caused more severe functional impairment. Significance of results In this delirium sample, advanced age and preexisting dementia, as well as brain cancer, terminal illness, infection, and delirium severity contributed to persistent delirium or late response, indicating a prolonged

  8. Effect of a Dietary Herbal Mixture Supplement on the Growth Performance, Egg Production and Health Status in Chickens

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    Vasko GERZILOV

    2015-06-01

    Full Text Available The experiment was carried out with dual-purpose fowls developed for rural backyard farming – indigenous Katunitsa chicken (line “AN”, in a free range management system from hatching to 52 weeks of age. The purpose of the investigation was to establish the influence of a blend of herbs as a dietary supplement on some serum biochemical parameters (alanine aminotransferase, aspartate aminotransferase, total cholesterol, gamma-glutamyl transferase, triglycerides and creatinine, growth performance, egg production, egg fatty acid composition, and health status. The composition of this blend of herbs included: 0.05% garlic powder (Allium sativum, 0.3% cinnamon powder (Cinnamomum verum and 0.03% of each of the following dried herbs: yarrow (Achillea millefolium, rosemary (Rosmarinus officinalis, thyme (Thymus serpyllum, basil (Ocimum basilicum and oregano (Origanum vulgare. The birds were divided into two groups – control (n=60 without supplemental mixture to the diet and experimental (n=700 with supplemental mixture to the diet from the first day of age to the end of the experiment. The results showed that the herbal mixture supplement decreased significantly the blood serum cholesterol and triglyceride levels – at 7 (P0.05. Over the entire investigation period the chickens from the experimental group had a better feed conversion ratio (with 3.37% and a higher egg laying capacity (with 1.79%. At the end of experiment (52 weeks of age, hens from the control group exhibited generalised fatty degeneration of liver parenchyma, while these in experimental group, the major part of hepatocytes had no fat droplets in their cytoplasm. The death rate from 0 to 7, from 8 to 21 and from 22 to 52 weeks of age was 18.33%, 0% and 8.57% in the control group and 1.00%, 0.26% and 2.62% in the experimental group, respectively. Therefore in conclusion, it can be affirmed that the use of this blend of herbs had a beneficial effect in the treated fowls and

  9. Stunting, poor iron status and parasite infection are significant risk factors for lower cognitive performance in Cambodian school-aged children.

    Directory of Open Access Journals (Sweden)

    Marlene Perignon

    Full Text Available BACKGROUND: Nutrition is one of many factors affecting the cognitive development of children. In Cambodia, 55% of children <5 y were anemic and 40% stunted in 2010. Currently, no data exists on the nutritional status of Cambodian school-aged children, or on how malnutrition potentially affects their cognitive development. OBJECTIVE: To assess the anthropometric and micronutrient status (iron, vitamin A, zinc, iodine of Cambodian schoolchildren and their associations with cognitive performance. METHODS: School children aged 6-16 y (n = 2443 from 20 primary schools in Cambodia were recruited. Anthropometry, hemoglobin, serum ferritin, transferrin receptors, retinol-binding protein and zinc concentrations, inflammation status, urinary iodine concentration and parasite infection were measured. Socio-economic data were collected in a sub-group of children (n = 616. Cognitive performance was assessed using Raven's Colored Progressive Matrices (RCPM and block design and picture completion, two standardized tests from the Wechsler Intelligence Scale for Children (WISC-III. RESULTS: The prevalence of anemia, iron, zinc, iodine and vitamin A deficiency were 15.7%; 51.2%, 92.8%, 17.3% and 0.7% respectively. The prevalence of stunting was 40.0%, including 10.9% of severe stunting. Stunted children scored significantly lower than non-stunted children on all tests. In RCPM test, boys with iron-deficiency anemia had lower scores than boys with normal iron status (-1.46, p<0.05. In picture completion test, children with normal iron status tended to score higher than iron-deficient children with anemia (-0.81; p = 0.067 or without anemia (-0.49; p = 0.064. Parasite infection was associated with an increase in risk of scoring below the median value in block design test (OR = 1.62; p<0.05, and with lower scores in other tests, for girls only (both p<0.05. CONCLUSION: Poor cognitive performance of Cambodian school-children was multifactorial and

  10. Clinical Neuropathology practice news 1-2014: Pyrosequencing meets clinical and analytical performance criteria for routine testing of MGMT promoter methylation status in glioblastoma

    Science.gov (United States)

    Preusser, Matthias; Berghoff, Anna S.; Manzl, Claudia; Filipits, Martin; Weinhäusel, Andreas; Pulverer, Walter; Dieckmann, Karin; Widhalm, Georg; Wöhrer, Adelheid; Knosp, Engelbert; Marosi, Christine; Hainfellner, Johannes A.

    2014-01-01

    Testing of the MGMT promoter methylation status in glioblastoma is relevant for clinical decision making and research applications. Two recent and independent phase III therapy trials confirmed a prognostic and predictive value of the MGMT promoter methylation status in elderly glioblastoma patients. Several methods for MGMT promoter methylation testing have been proposed, but seem to be of limited test reliability. Therefore, and also due to feasibility reasons, translation of MGMT methylation testing into routine use has been protracted so far. Pyrosequencing after prior DNA bisulfite modification has emerged as a reliable, accurate, fast and easy-to-use method for MGMT promoter methylation testing in tumor tissues (including formalin-fixed and paraffin-embedded samples). We performed an intra- and inter-laboratory ring trial which demonstrates a high analytical performance of this technique. Thus, pyrosequencing-based assessment of MGMT promoter methylation status in glioblastoma meets the criteria of high analytical test performance and can be recommended for clinical application, provided that strict quality control is performed. Our article summarizes clinical indications, practical instructions and open issues for MGMT promoter methylation testing in glioblastoma using pyrosequencing. PMID:24359605

  11. School Performance, Status Relations, and the Structure of Sentiment: Bringing the Teacher Back In. Report No. 9.

    Science.gov (United States)

    Alexander, Karl L.; And Others

    Previous research has failed to support the widely held assumption that the academic difficulties experienced by many minority and low socioeconomic status youth are due to their "outsider" standing vis-a-vis the middle class culture thought to govern the social relations of schooling. This analysis suggests that this proposition errs in…

  12. Undernutrition, fatty acid and micronutrient status in relation to cognitive performance in Indian school children: a cross-sectional study

    NARCIS (Netherlands)

    Eilander, A.; Muthayya, S.; Knaap, van der H.; Srinivasan, K.; Thomas, T.; Kok, F.J.; Kurpad, A.V.; Osendarp, S.J.M.

    2010-01-01

    While undernutrition and anaemia have previously been linked to poor development of children, relatively little is known about the role of B-vitamins and fatty acids on cognition. The present study aims to explore the associations between indicators of body size, fatty acid and micronutrient status

  13. Radioactive waste isolation in salt: special advisory report on the status of the Office of Nuclear Waste Isolation's plans for repository performance assessment

    International Nuclear Information System (INIS)

    Ditmars, J.D.; Walbridge, E.W.; Rote, D.M.; Harrison, W.; Herzenberg, C.L.

    1983-10-01

    Repository performance assessment is analysis that identifies events and processes that might affect a repository system for isolation of radioactive waste, examines their effects on barriers to waste migration, and estimates the probabilities of their occurrence and their consequences. In 1983 Battelle Memorial Institute's Office of Nuclear Waste Isolation (ONWI) prepared two plans - one for performance assessment for a waste repository in salt and one for verification and validation of performance assessment technology. At the request of the US Department of Energy's Salt Repository Project Office (SRPO), Argonne National Laboratory reviewed those plans and prepared this report to advise SRPO of specific areas where ONWI's plans for performance assessment might be improved. This report presents a framework for repository performance assessment that clearly identifies the relationships among the disposal problems, the processes underlying the problems, the tools for assessment (computer codes), and the data. In particular, the relationships among important processes and 26 model codes available to ONWI are indicated. A common suggestion for computer code verification and validation is the need for specific and unambiguous documentation of the results of performance assessment activities. A major portion of this report consists of status summaries of 27 model codes indicated as potentially useful by ONWI. The code summaries focus on three main areas: (1) the code's purpose, capabilities, and limitations; (2) status of the elements of documentation and review essential for code verification and validation; and (3) proposed application of the code for performance assessment of salt repository systems. 15 references, 6 figures, 4 tables

  14. Importance of Extracranial Disease Status and Tumor Subtype for Patients Undergoing Radiosurgery for Breast Cancer Brain Metastases

    Energy Technology Data Exchange (ETDEWEB)

    Dyer, Michael A.; Kelly, Paul J. [Department of Radiation Oncology, Dana-Farber/Brigham and Women' s Cancer Center, Boston, MA (United States); Harvard Medical School, Boston, MA (United States); Chen, Yu-Hui [Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA (United States); Pinnell, Nancy E. [Department of Radiation Oncology, Dana-Farber/Brigham and Women' s Cancer Center, Boston, MA (United States); Claus, Elizabeth B. [Harvard Medical School, Boston, MA (United States); Department of Neurosurgery, Brigham and Women' s Hospital, Boston, MA (United States); Yale University School of Medicine, New Haven, CT (United States); Lee, Eudocia Q. [Harvard Medical School, Boston, MA (United States); Center for Neuro-Oncology, Dana-Farber/Brigham and Women' s Center, Boston, MA (United States); Weiss, Stephanie E. [Department of Radiation Oncology, Dana-Farber/Brigham and Women' s Cancer Center, Boston, MA (United States); Harvard Medical School, Boston, MA (United States); Arvold, Nils D. [Harvard Radiation Oncology Program, Boston, MA (United States); Lin, Nancy U. [Harvard Medical School, Boston, MA (United States); Department of Medical Oncology, Dana-Farber/Brigham and Women' s Cancer Center, Boston, MA (United States); Alexander, Brian M., E-mail: bmalexander@lroc.harvard.edu [Department of Radiation Oncology, Dana-Farber/Brigham and Women' s Cancer Center, Boston, MA (United States); Harvard Medical School, Boston, MA (United States)

    2012-07-15

    Purpose: In this retrospective study, we report on outcomes and prognostic factors for patients treated with stereotactic radiosurgery (SRS) for breast cancer brain metastases. Methods and Materials: We identified 132 consecutive patients with breast cancer who were treated with SRS for brain metastases from January 2000 through June 2010. We retrospectively reviewed records of the 51 patients with adequate follow-up data who received SRS as part of the initial management of their brain metastases. Overall survival (OS) and time to central nervous system (CNS) progression from the date of SRS were calculated using the Kaplan-Meier method. Prognostic factors were evaluated using the Cox proportional hazards model. Results: Triple negative subtype was associated with CNS progression on univariate analysis (hazard ratio [HR] = 5.0, p = 0.008). On multivariate analysis, triple negative subtype (HR = 8.6, p = 0.001), Luminal B subtype (HR = 4.3, p = 0.03), and omission of whole-brain radiation therapy (HR = 3.7, p = 0.02) were associated with CNS progression. With respect to OS, Karnofsky Performance Status (KPS) {<=} 80% (HR = 2.0, p = 0.04) and progressive extracranial disease (HR = 3.1, p = 0.002) were significant on univariate analysis; KPS {<=} 80% (HR = 4.1, p = 0.0004), progressive extracranial disease (HR = 6.4, p < 0.0001), and triple negative subtype (HR = 2.9, p = 0.04) were significant on multivariate analysis. Although median survival times were consistent with those predicted by the breast cancer-specific Graded Prognostic Assessment (Breast-GPA) score, the addition of extracranial disease status further separated patient outcomes. Conclusions: Tumor subtype is associated with risk of CNS progression after SRS for breast cancer brain metastases. In addition to tumor subtype and KPS, which are incorporated into the Breast-GPA, progressive extracranial disease may be an important prognostic factor for OS.

  15. Intraindividual variability in cognitive performance in three groups of older adults: cross-domain links to physical status and self-perceived affect and beliefs.

    Science.gov (United States)

    Strauss, Esther; MacDonald, Stuart W S; Hunter, Michael; Moll, Alex; Hultsch, David F

    2002-11-01

    Intraindividual variability of physical status and affect/beliefs as well as their relations with cognition were examined in 3 groups of older adults: healthy elderly, individuals with a nonneurological health-related disturbance (arthritis) and people with neurological compromise (dementia). The findings showed that greater inconsistency in physical performance was observed in groups characterized by central nervous system dysfunction. By contrast, fluctuations in affect appeared to reflect other more transient sources, such as pain. In general, increased inconsistency in non-cognitive domains was associated with poorer cognitive function. There were cross-domain links between inconsistency in physical functioning and fluctuations in cognitive performance, although the nature of the links depended largely upon the neurological status of the individuals. Considered together, the result indicated that measures of cognitive as well as physical variability are important behavioral markers of neurological integrity.

  16. Practice status of specialized agencies for occupational health management of small- to medium-size enterprises and the factors improving their performance: a cross-sectional survey study.

    Science.gov (United States)

    Lee, Saerom; Myong, Jun-Pyo; Kim, Eun-A; Eom, Huisu; Choi, Bowha; Kang, Young Joong

    2017-01-01

    We examined the current status of specialized agencies for occupational health management (SAs) and their workforce. Furthermore, we aimed to clarify the current practice status of SA healthcare professionals and factors that influence their performance. To examine the current SA workforce, we analyzed data from the 2014 Survey of Current Status of SA and their Workforce from the Ministry of Employment and Labor (MOEL). Furthermore, we mailed out an original questionnaire to SA professionals to determine their current health management status and factors that affect their performance. Data from the respondents ( N  = 384) were analyzed. In 2014, the workforce performing health management in SAs comprised 232 physicians, 507 nurses, and 312 occupational hygienists, with no significant regional differences in the distribution of physicians and nurses. According to the findings of the questionnaire, the average daily number of worker consultations by physicians and nurses was 22.8, while the average time taken for health management ranged from 74.3 to 104.3 min, depending on the size of the firm. Most of the respondents (41.5%) answered that they were following-up on more than 80% of individuals with illnesses. Among health management tasks, performance scores of "consultations for general diseases" and "consultations for lifestyle habits" were relatively high, whereas health promotion activities at workplaces were relatively low. There was a significant correlation between the utilization of general and special health examination results and task performance. Among health management tasks, follow-up management of individuals with illnesses and consultations for disease/lifestyle habits were relatively well performed, whereas health promotion activities at workplaces were not performed well. Among factors that positively influenced SA performance at workplaces, only the utilization of health examination results had significant effects. Therefore, to accomplish

  17. Adolescent Work Intensity, School Performance, and Substance Use: Links Vary by Race/Ethnicity and Socioeconomic Status

    OpenAIRE

    Bachman, Jerald G.; Patrick, Jeremy Staff; O’Malley, M.; Freedman-Doan, Peter

    2013-01-01

    High school students who spend long hours in paid employment during the school year are at increased risk of lower grades and higher substance use, although questions remain about whether these linkages reflect causation or prior differences (selection effects). Questions also remain about whether such associations vary by socioeconomic status (SES) and race/ethnicity. This study examines those questions using nationally representative data from two decades (1991–2010) of annual Monitoring th...

  18. Physical activity and cohabitation status moderate the link between diabetes mellitus and cognitive performance in a community-dwelling elderly population in Germany

    Science.gov (United States)

    Buchmann, Nikolaus; Tegeler, Christina; Steinhagen-Thiessen, Elisabeth

    2017-01-01

    Aims/Hypothesis The increasing number of people with dementia and cognitive impairments makes it essential to detect and prevent modifiable risk factors of dementia. This study focuses on type 2 diabetes mellitus, especially on undiagnosed cases and their increased risk of cognitive impairment. Furthermore, the potential of physical activity and social integration to moderate the relation between diabetes and cognitive impairment is assessed. Methods We used cross-sectional data from 1299 participants of the Berlin Aging Study II (BASE-II) aged between 60 to 84 years and performed logistic regression models to analyze the association of diabetes status, physical activity, and cohabitation status with poor cognitive performance. Cognitive performance was measured with the Consortium to Establish a Registry for Alzheimer's Disease (CERAD)-Plus test battery. Results Undiagnosed diabetes (odds ratio (OR) = 2.12, p = 0.031), physical inactivity (OR = 1.43, p = 0.008) and non-cohabiting (OR = 1.58, p = 0.002) were associated with an increased likelihood of poor cognitive performance. The highest odds were observed in participants who suffered from undiagnosed or insulin-dependent diabetes and, in addition, were inactive (undiagnosed diabetes: OR = 3.44, p = 0.003; insulin-dependent diabetes: OR = 6.19, p = 0.019) or lived alone (undiagnosed diabetes: OR = 4.46, p = 0.006; insulin-dependent diabetes: OR = 6.46 p = 0.052). Physical activity and cohabiting appeared to be beneficial. Conclusions/Interpretation Physical activity and cohabitation status moderate the link between diabetes mellitus and cognitive performance. Special attention should be paid to undiagnosed and insulin-dependent diabetes cases, which have a particularly high risk of poor cognitive performance. PMID:29073237

  19. General Health Status, Music Performance Anxiety, and Coping Methods of Musicians Working in Turkish State Symphony Orchestras: A Cross-Sectional Study.

    Science.gov (United States)

    Topoğlu, Onur; Karagülle, Derya; Keskin, Tuba U; Abacigil, Filiz; Okyay, Pinar

    2018-06-01

    This study assessed the general health, music performance anxiety (MPA), and coping methods of musicians working in six state orchestras in Turkey. All musicians working in the state symphony orchestras (n=384) were invited to participate in the study. In face-to-face interviews, the authors administered a questionnaire, which consisted of five sections: sociodemographic information, history of musical performance, health status, general health questionnaire-12 (GHQ-12), and MPA scale. Mann-Whitney U-test, Student's t-test, and Spearman's correlation test were used to analyze the questionnaire data. The 220 musicians who participated included 121 (55%) males and 99 (45%) females, with a mean age of 42.4±11.3 yrs. For musculoskeletal symptoms, 87.6% reported at least one symptom with the most common being pain. For general health status, the GHQ-12 showed 64% of musicians were at low risk, 18.7% at moderate risk, and 17.3% at high risk in terms of mental health. The prevalence of MPA before or during performance was 81.8%, and 60% of musicians stated that performance anxiety negatively affected their performances. Results indicate that musicians working in Turkish state symphony orchestras encounter numerous health problems (tinnitus, hearing loss, musculoskeletal symptoms, etc.) due to their profession. No specific health support is provided, especially education and health service provision.

  20. A global, cross cultural study examining the relationship between employee health risk status and work performance metrics.

    Science.gov (United States)

    Howarth, Ana; Quesada, Jose; Mills, Peter R

    2017-01-01

    Health risk assessments (HRA) are used by many organisations as a basis for developing relevant and targeted employee health and well-being interventions. However, many HRA's have a western-centric focus and therefore it is unclear whether the results can be directly extrapolated to those from non-western countries. More information regarding the differences in the associations between country status and health risks is needed along with a more global perspective of employee health risk factors and well-being overall. Therefore we aimed to i) quantify and compare associations for a number of health risk factors based on country status, and then ii) explore which characteristics can aid better prediction of well-being levels and in turn workplace productivity globally. Online employee HRA data collected from 254 multi-national companies, for the years 2013 through 2016 was analysed (n = 117,274). Multiple linear regression models were fitted, adjusting for age and gender, to quantify associations between country status and health risk factors. Separate regression models were used to assess the prediction of well-being measures related to productivity. On average, the developing countries were comprised of younger individuals with lower obesity rates and markedly higher job satisfaction compared to their developed country counterparts. However, they also reported higher levels of anxiety and depression, a greater number of health risks and lower job effectiveness. Assessment of key factors related to productivity found that region of residency was the biggest predictor of presenteeism and poor pain management was the biggest predictor of absenteeism. Clear differences in health risks exist between employees from developed and developing countries and these should be considered when addressing well-being and productivity in the global workforce.

  1. Effects of Visual Communication Tool and Separable Status Display on Team Performance and Subjective Workload in Air Battle Management

    National Research Council Canada - National Science Library

    Schwartz, Daniel; Knott, Benjamin A; Galster, Scott M

    2008-01-01

    ... ambient cabin noise while performing several visual and manual tasks. The purpose of this study is to compare team performance and subjective workload on a simulated AWACS scenario, for two conditions of communication...

  2. Survival analysis in patients with metastatic spinal disease: the influence of surgery, histology, clinical and neurologic status

    Directory of Open Access Journals (Sweden)

    Matheus Fernandes de Oliveira

    2015-04-01

    Full Text Available Spine is the most common site for skeletal metastasis in patients with malignancy. Vertebral involvement quantification, neurological status, general health status and primary tumor histology are factors to set surgical planning and therapeutic targets. We evaluated the impact of general clinical and neurological status, histologic type and surgery in survival. Method : The study sample consisted of consecutive patients admitted from July 2010 to January 2013 for treatment. Results : Sixty eight patients were evaluated. 23 were female and 45 were male. Main primary neoplasic sites were: breast, prostate, lung/pleura and linfoproliferative. Thirty three out of 68 received surgical treatment, 2 received percutaneous biopsy and 33 had nonsurgical treatment. Survival : Log Rank curves revealed no statistical significant difference according to histological type, surgical approach and Frankel Score. Karnofsky Score was statistically different. Conclusion : Histological type and clinical status were statistically associated with life expectancy in vertebral metastatic disease.

  3. Making the middle classes on shifting ground? Residential status, performativity and middle-class subjectivities in contemporary London.

    Science.gov (United States)

    Benson, Michaela; Jackson, Emma

    2017-06-01

    This paper argues that shifts in access to housing - both in relation to rental and ownership - disrupt middle-class reproduction in ways that fundamentally influence class formation. While property ownership has had a long association with middle-class identities, status and distinction, an increasingly competitive rental market alongside inflated property prices has impacted on expectations and anxieties over housing futures. In this paper, we consider two key questions: (1) What happens to middle-class identities under the conditions of this wider structural change? (2) How do the middle classes variously manoeuvre within this? Drawing on empirical research conducted in London, we demonstrate that becoming an owner-occupier may be fractured along lines of class but also along the axes of age, wealth and timing, particularly as this relates to the housing market. It builds on understandings of residential status and place as central to the formation of class, orienting this around the recognition of both people and place as mutable, emphasizing that changing economic and social processes generate new class positionalities and strategies for class reproduction. We argue that these processes are writ large in practices of belonging and claims to place, with wider repercussions within the urban landscape. © London School of Economics and Political Science 2017.

  4. Does inclusion of education and marital status improve SCORE performance in central and eastern europe and former soviet union? findings from MONICA and HAPIEE cohorts.

    Directory of Open Access Journals (Sweden)

    Olga Vikhireva

    Full Text Available The SCORE scale predicts the 10-year risk of fatal atherosclerotic cardiovascular disease (CVD, based on conventional risk factors. The high-risk version of SCORE is recommended for Central and Eastern Europe and former Soviet Union (CEE/FSU, due to high CVD mortality rates in these countries. Given the pronounced social gradient in cardiovascular mortality in the region, it is important to consider social factors in the CVD risk prediction. We investigated whether adding education and marital status to SCORE benefits its prognostic performance in two sets of population-based CEE/FSU cohorts.The WHO MONICA (MONItoring of trends and determinants in CArdiovascular disease cohorts from the Czech Republic, Poland (Warsaw and Tarnobrzeg, Lithuania (Kaunas, and Russia (Novosibirsk were followed from the mid-1980s (577 atherosclerotic CVD deaths among 14,969 participants with non-missing data. The HAPIEE (Health, Alcohol, and Psychosocial factors In Eastern Europe study follows Czech, Polish (Krakow, and Russian (Novosibirsk cohorts from 2002-05 (395 atherosclerotic CVD deaths in 19,900 individuals with non-missing data.In MONICA and HAPIEE, the high-risk SCORE ≥5% at baseline strongly and significantly predicted fatal CVD both before and after adjustment for education and marital status. After controlling for SCORE, lower education and non-married status were significantly associated with CVD mortality in some samples. SCORE extension by these additional risk factors only slightly improved indices of calibration and discrimination (integrated discrimination improvement <5% in men and ≤1% in women.Extending SCORE by education and marital status failed to substantially improve its prognostic performance in population-based CEE/FSU cohorts.

  5. The effects of fatty fish intake on adolescents' nutritional status and associations with attention performance: results from the FINS-TEENS randomized controlled trial.

    Science.gov (United States)

    Handeland, Katina; Skotheim, Siv; Baste, Valborg; Graff, Ingvild E; Frøyland, Livar; Lie, Øyvind; Kjellevold, Marian; Markhus, Maria W; Stormark, Kjell M; Øyen, Jannike; Dahl, Lisbeth

    2018-02-23

    Adolescence involves changes in dietary habits that may induce imbalances in the intake of different nutrients. Fish is an important dietary source of omega-3 (n-3) long-chain polyunsaturated fatty acids (LCPUFAs), vitamin D, several minerals and high-quality protein. By using secondary outcomes and exploratory analyses, the aims of this paper were to evaluate if nutritional biomarkers (red blood cell fatty acids, serum (s)-25(OH)D, s-ferritin and urinary iodine concentration (UIC)) were altered during a dietary intervention, and if they mediated previously reported changes in attention performance. In addition, to examine the status of the biomarkers and explore associations between dietary pattern, biomarkers and attention performance cross-sectionally at baseline. The Fish Intervention Studies-TEENS (FINS-TEENS) was a three-armed intervention trial, including adolescents from eight secondary schools (n = 415; age: 14-15y) in Bergen, Norway. Participants were individually randomized to receive either fish meals, meat meals or n-3 LCPUFA supplements, three times a week for a total of 12 weeks. Blood and urine samples were collected pre and post intervention and attention performance was assessed with the d2 test of attention. Analyses of covariance (ANCOVA) assessed differences between groups in changes of biomarkers and linear mixed models were applied in analyses of attention performance and biomarkers. The trial is registered in ClinicalTrials.gov (NCT02350322). At baseline, the mean omega-3 index was 5.8 ± 1.3% and deficient status were identified for s-25(OH)D (54%), s-ferritin (10%) and UIC (40%). The intervention resulted in an increase in DHA and the omega-3 index which was larger in the supplement group compared to the fish and meat group (P < 0.01), and in the fish group compared to the meat group (P < 0.01). No differences between the groups were observed for changes in 25(OH)D, s-ferritin or UIC. None of the biomarkers mediated

  6. The Association of Self-Reported Sleep, Weight Status, and Academic Performance in Fifth-Grade Students

    Science.gov (United States)

    Stroebele, Nanette; McNally, Janise; Plog, Amy; Siegfried, Scott; Hill, James O.

    2013-01-01

    Background: To improve support and justi?cation for health promotion efforts in schools, it is helpful to understand how students' health behaviors affect academic performance. Methods: Fifth-grade students completed an online school-administered health survey with questions regarding their eating behavior, physical activity, academic performance,…

  7. A Review on the Role of Chromium Supplementation in Ruminant Nutrition-Effects on Productive Performance, Blood Metabolites, Antioxidant Status, and Immunocompetence

    DEFF Research Database (Denmark)

    Lashkari, Saman; Habibian, Mahmood; Jensen, Søren Krogh

    2018-01-01

    , Cr supplementation improved dry matter intake, milk production, and milk composition of dairy cows in the early, mid, or late stage of lactation. Also, in some studies, performance of growing animal, immune response, and some blood parameters responded positively to Cr supplementation. In conclusion...... microminerals is important. Chromium (Cr) is one of the important micronutrients which plays an important role in metabolism of ruminants. Experimental studies have found that Cr could change performance, immune responses, glucose and fatty acid metabolism, and antioxidant status in dairy cows. In some studies......, the effects of Cr supplementation on performance of ruminants are inconsistent; however, its long-term effects on health, productivity, immune system, and antioxidant activity of ruminants still need to be investigated....

  8. Regulation of carnitine status in ruminants and efficacy of carnitine supplementation on performance and health aspects of ruminant livestock: a review.

    Science.gov (United States)

    Ringseis, Robert; Keller, Janine; Eder, Klaus

    2018-02-01

    Carnitine has long been known to play a critical role for energy metabolism. Due to this, a large number of studies have been carried out to investigate the potential of supplemental carnitine in improving performance of livestock animals including ruminants, with however largely inconsistent results. An important issue that has to be considered when using carnitine as a feed additive is that the efficacy of supplemental carnitine is probably dependent on the animal's carnitine status, which is affected by endogenous carnitine synthesis, carnitine uptake from the gastrointestinal tract and carnitine excretion. The present review aims to summarise the current knowledge of the regulation of carnitine status and carnitine homeostasis in ruminants, and comprehensively evaluate the efficacy of carnitine supplementation on performance and/or health in ruminant livestock by comparing the outcomes of studies with carnitine supplementation in dairy cattle, growing and finishing cattle and sheep. While most of the studies show that supplemental carnitine, even in ruminally unprotected form, is bioavailable in ruminants, its effect on either milk or growth performance is largely disappointing. However, supplemental carnitine appears to be a useful strategy to offer protection against ammonia toxicity caused by consumption of high levels of non-protein N or forages with high levels of soluble N both, in cattle and sheep.

  9. Extended, continuous measures of functional status in community dwelling persons with Alzheimer's and related dementia: Infrastructure, performance, tradeoffs, preliminary data, and promise.

    Science.gov (United States)

    Zylstra, Bradley; Netscher, George; Jacquemot, Julien; Schaffer, Michael; Shen, Galen; Bowhay, Angela D; Braley, Tamara L; Possin, Katherine L; Miller, Bruce L; Bayen, Alexandre M; Bonasera, Stephen J; Schenk, A Katrin

    2018-04-15

    The past decades have seen phenomenal growth in the availability of inexpensive and powerful personal computing devices. Efforts to leverage these devices to improve health care outcomes promise to remake many aspects of healthcare delivery, but remain in their infancy. We describe the development of a mobile health platform designed for daily measures of functional status in ambulatory, community dwelling subjects, including those who have Alzheimer's disease or related neurodegenerative disorders. Using Smartwatches and Smartphones we measure subject overall activity and outdoor location (to derive their lifespace). These clinically-relevant measures allow us to track a subject's functional status in their natural environment over prolonged periods of time without repeated visits to healthcare providers. Functional status metrics are integrated with medical information and caregiver reports, which are used by a caregiving team to guide referrals for physician/APRN/NP care. COMPARISON: with Existing Methods We describe the design tradeoffs involved in all aspects of our current system architecture, focusing on decisions with significant impact on system cost, performance, scalability, and user-adherence. We provide real-world data from current subject enrollees demonstrating system accuracy and reliability. We document real-world feasibility in a group of men and women with dementia that Smartwatches/Smartphones can provide long-term, relevant clinical data regarding individual functional status. We describe the underlying considerations of this system so that interested organizations can adapt and scale our approach to their needs. Finally, we provide a potential agenda to guide development of future systems. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. Concordance of Barthel Index, ECOG-PS, and Palliative Performance Scale in the assessment of functional status in patients with advanced medical diseases.

    Science.gov (United States)

    Hernández-Quiles, C; Bernabeu-Wittel, M; Pérez-Belmonte, L M; Macías-Mir, P; Camacho-González, D; Massa, B; Maiz-Jiménez, M; Ollero-Baturone, M

    2017-09-01

    Analysing most relevant clinical features and concordance between different functional scales in patients with advanced medical diseases (PAMD). Cross-sectional multicentre study that included PAMD (heart, lung, kidney, liver, and neurological diseases) in hospital settings from February 2009 to October 2010. We analysed clinical, biological and functional features in performing activities of daily living (ADL) by medians of Barthel Index (BI); additionally we assessed their performance status by medians of Eastern Cooperative Oncology Group-Performance Status (ECOG-PS) and Palliative Performance Scale (PPS) scores. We evaluated the concordance of these instruments in assessing functional impairment by κ and intraclass correlation coefficient tests. 1847 patients were included (average age 79 years, 50.1% men). Most common symptoms were dyspnoea (62.31%), asthenia (23%) and delirium (20.14%). Functional assessment showed a high prevalence of severe or total impairment in performing basic ADL by medians of used instruments (BI median=35 (IQR=70), and 52.1% of patients with severe-total impairment; ECOG-PS median=2 (IQR 30), and 44% of patients with severe-total impairment; and PPS median=50 (IQR 30), and 32% of patients with severe-total impairment). Concordance among these instruments was acceptably good ( κ indexes ranging from 0.653 to 0.745 (pmanagement. Assessment of functional ability in this population by BI, ECOG-PS, and PPS showed good concordance. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  11. Effects of Dietary Calcium Levels on Productive Performance, Eggshell Quality and Overall Calcium Status in Aged Laying Hens

    Directory of Open Access Journals (Sweden)

    S. H. An

    2016-10-01

    Full Text Available This study was conducted to investigate the effects of diets with varying levels of calcium on egg production, shell quality and overall calcium status in aged laying hens. A total of five hundred 70-wk-old Hy-Line Brown layers were divided five groups and fed one of the five experimental diets with 3.5%, 3.8%, 4.1%, 4.4%, or 4.7% Ca, for 10 weeks. There were no significant differences in feed intake, egg production and egg weight among groups. The cracked eggs were linearly reduced as dietary Ca levels increased to 4.7% (p<0.01. A significant linear improvement for eggshell strength and thickness were determined with increasing dietary Ca levels (p<0.01. The contents of serum Ca and phosphorus were not affected by dietary Ca levels. With increase in dietary Ca levels, the tibial breaking strength slightly increased. There were no significant differences in the tibial contents of ash, Ca and phosphorus among groups. In conclusion, eggshell quality, as measured by appearance, strength and thickness of eggshell, were influenced by dietary Ca content as expected (p<0.05. These results suggested that aged laying hens require relatively higher level of Ca than required levels from current Korean feeding standards for poultry.

  12. Effect of pad-fan cooling and dietary organic acid supplementation during late gestation and lactation on reproductive performance and antioxidant status of multiparous sows in hot weather.

    Science.gov (United States)

    Chen, Jun; Guo, Ji; Guan, Wu-Tai; Song, Jun-Jie; Deng, Zi-Xiao; Cheng, Lin; Deng, Yue-Lin; Chen, Fang; Zhang, Shi-Hai; Zhang, Yin-Zi; Yang, Fei; Ren, Chun-Xiao; Wang, Chao-Xian

    2018-06-01

    A 2 × 2 factorial arrangement (rearing room with or without pad-fan cooling × diet with or without 2.5 kg/t organic acid) was used to evaluate the effect of pad-fan cooling and dietary organic acid supplementation during perinatal period on reproductive performance and antioxidant status of sows in hot weather. This study was conducted in a subtropical city in Guangdong Province in South China between August and October, 2015. At day 85 of gestation, a total of 112 sows were randomly assigned to the four treatments with 28 sows per treatment, and maintained until day 21 of lactation, and the feeding trial lasted for 51 days. During the experimental period, room temperature and humidity were recorded hourly. The lactation feed intake of sows (P = 0.109) and stillbirths (P fan cooling against the room without pad-fan cooling. The number of weak newborns per litter and the malondialdehyde content in days 14 and 21 milk decreased (P fan cooling in rearing room improved the lactation feed intake of sows, and dietary organic acid supplementation improved reproductive performance and milk antioxidant status of sows. Pad-fan cooling is recommended in farrowing room, but not in gestating room.

  13. Comparison of an inflammation-based prognostic score (GPS) with performance status (ECOG-ps) in patients receiving palliative chemotherapy for gastroesophageal cancer.

    Science.gov (United States)

    Crumley, Andrew B C; Stuart, Robert C; McKernan, Margaret; McDonald, Alexander C; McMillan, Donald C

    2008-08-01

    The aim of the present study was to compare an inflammation-based prognostic score (Glasgow Prognostic Score, GPS) with performance status (ECOG-ps) in patients receiving platinum-based chemotherapy for palliation of gastroesophageal cancer. Sixty-five patients presenting with gastroesophageal carcinoma to the Royal Infirmary, Glasgow between January 1999 and December 2005 and who received palliative chemotherapy or chemo-radiotherapy were studied. ECOG-ps, C-reactive protein, and albumin were recorded at diagnosis. Patients with both an elevated C-reactive protein (>10 mg/L) and hypoalbuminemia (L) were allocated a GPS of 2. Patients in whom only one of these biochemical abnormalities was present were allocated a GPS of 1 and patients with a normal C-reactive protein and albumin were allocated a score of 0. Toxicity was recorded using the Common Toxicity Criteria. The minimum follow up was 14 months. During the follow-up period, 59 (91%) of the patients died. On univariate and multivariate survival analysis, only the GPS (hazard ratios 1.65, 95% CI 1.10-2.47, P GPS of 0, those patients with a GPS of 1 or 2 required more frequent chemotherapy dose reduction (P GPS, appears to be superior to the subjective assessment of performance status (ECOG-ps) in predicting the response to platinum-based chemotherapy in patients with advanced gastroesophageal cancer.

  14. Adolescent work intensity, school performance, and substance use: links vary by race/ethnicity and socioeconomic status.

    Science.gov (United States)

    Bachman, Jerald G; Staff, Jeremy; O'Malley, Patrick M; Freedman-Doan, Peter

    2013-11-01

    High school students who spend long hours in paid employment during the school year are at increased risk of lower grades and higher substance use, although questions remain about whether these linkages reflect causation or prior differences (selection effects). Questions also remain about whether such associations vary by socioeconomic status (SES) and race/ethnicity. This study examines those questions using nationally representative data from two decades (1991-2010) of annual Monitoring the Future surveys involving about 600,000 students in 10th and 12th grades. White students are consistently more likely than minority students to hold paid employment during the school year. Among White and Asian American students, paid work intensity is negatively related to parental education and grade point averages (GPA) and is positively related to substance use. Also among Whites and Asian Americans, students with the most highly educated parents show the strongest negative relations between work intensity and GPA, whereas the links are weaker for those with less educated parents (i.e., lower SES levels). All of these relations are less evident for Hispanic students and still less evident for African American students. It thus appears that any costs possibly attributable to long hours of student work are most severe for those who are most advantaged--White or Asian American students with highly educated parents. Working long hours is linked with fewer disadvantages among Hispanic students and especially among African American students. Youth employment dropped in 2008-2010, but the relations described above have shown little change over two decades.

  15. Influence of Age and Nutritional Status on Flight Performance of the Asian Tiger Mosquito Aedes albopictus (Diptera: Culicidae

    Directory of Open Access Journals (Sweden)

    Lauren F. Collins

    2013-07-01

    Full Text Available The Asian tiger mosquito, Aedes albopictus, is a competent vector for arboviruses and recently was implicated as the vector of the first autochthonous cases of dengue and chikungunya in southern Europe. The objective of this study was to analyze the flight performance of female Ae. albopictus of different ages that were starved, sugar-fed, or sugar-fed and blood-fed, using flight mills. After three days of starvation post emergence, females flew an average distance of 0.7 ± 0.5 km in 1.9 ± 1.5 h during a 16 h trial period, whereas sugar- or sugar- and blood-fed females of this age covered a significantly higher distance of around 3 km with a mean total flight time of around 6 h. The age of females (up to four weeks had no effect on performance. The average of maximal continuous flight segments of sugar-fed (2.14 ± 0.69 h and blood-fed (3.17 ± 0.82 h females was distinctly higher than of starved females (0.38 ± 0.15 h of which most flyers (83% performed maximal flight segments that lasted no longer than 0.5 h. Overall, the results for the laboratory monitored flight performance of Ae. albopictus confirm their ability to disperse a few kilometres between breeding site and host.

  16. Status of Job Motivation and Job Performance of Field Level Extension Agents in Ogun State: Implications for Agricultural Development

    Science.gov (United States)

    Fabusoro, E.; Awotunde, J. A.; Sodiya, C. I.; Alarima, C. I.

    2008-01-01

    The field level extension agents (FLEAs) are the lifeline of the agricultural extension system in Nigeria. Their motivation and job performance are therefore important to achieving faster agricultural development in Nigeria. The study identified the factors motivating the FLEAs working with Ogun State Agricultural development programme (OGADEP)…

  17. Correlation of hospital magnet status with the quality of physicians performing neurosurgical procedures in New York State.

    Science.gov (United States)

    Bekelis, Kimon; Missios, Symeon; MacKenzie, Todd A

    2018-01-24

    The quality of physicians practicing in hospitals recognized for nursing excellence by the American Nurses Credentialing Center has not been studied before. We investigated whether Magnet hospital recognition is associated with higher quality of physicians performing neurosurgical procedures. We performed a cohort study of patients undergoing neurosurgical procedures from 2009-2013, who were registered in the New York Statewide Planning and Research Cooperative System (SPARCS) database. Propensity score adjusted multivariable regression models were used to adjust for known confounders, with mixed effects methods to control for clustering at the facility level. An instrumental variable analysis was used to control for unmeasured confounding and simulate the effect of a randomized trial. During the study period, 185,277 patients underwent neurosurgical procedures, and met the inclusion criteria. Of these, 66,607 (35.6%) were hospitalized in Magnet hospitals, and 118,670 (64.4%) in non-Magnet institutions. Instrumental variable analysis demonstrated that undergoing neurosurgical operations in Magnet hospitals was associated with a 13.6% higher chance of being treated by a physician with superior performance in terms of mortality (95% CI, 13.2% to 14.1%), and a 4.3% higher chance of being treated by a physician with superior performance in terms of length-of-stay (LOS) (95% CI, 3.8% to 4.7%) in comparison to non-Magnet institutions. The same associations were present in propensity score adjusted mixed effects models. Using a comprehensive all-payer cohort of neurosurgical patients in New York State we identified an association of Magnet hospital recognition with superior physician performance.

  18. Quality of life, symptom status and physical performance in patients with advanced non-small cell lung cancer undergoing chemotherapy: an exploratory analysis of secondary data.

    Science.gov (United States)

    Shallwani, Shirin M; Simmonds, Maureen J; Kasymjanova, Goulnar; Spahija, Jadranka

    2016-09-01

    Our objectives were: (a) to identify predictors of change in health-related quality of life (HRQOL) in patients with advanced non-small cell lung cancer (NSCLC) undergoing chemotherapy; and (b) to characterize symptom status, nutritional status, physical performance and HRQOL in this population and to estimate the extent to which these variables change following two cycles of chemotherapy. A secondary analysis of a longitudinal observational study of 47 patients (24 men and 23 women) with newly diagnosed advanced NSCLC receiving two cycles of first-line chemotherapy was performed. Primary outcomes were changes in HRQOL (physical and mental component summaries (PCS and MCS) of the 36-item Short-Form Health Survey (SF-36)). Predictors in the models included pre-chemotherapy patient-reported symptoms (Schwartz Cancer Fatigue Scale (SCFS) and Lung Cancer Subscale), nutritional screening (Patient-Generated Subjective Global Assessment) and physical performance measures (6-min Walk Test (6MWT), one-minute chair rise test and grip strength). Mean SF-36 PCS score, 6MWT distance and grip strength declined following two cycles of chemotherapy (pmental component of HRQOL accounting for 13% and 9% of the variance, respectively. No significant predictors were found for change in the physical component of HRQOL. Pre-chemotherapy 6MWT distance and fatigue severity predicted change in the mental component of HRQOL in patients with advanced NSCLC undergoing chemotherapy, while physical performance declined during treatment. Clinical management of these factors may be useful for HRQOL optimization in this population. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  19. Performance testing of dosimetry processors, status of NRC rulemaking for improved personnel dosimetry processing, and some beta dosimetry and instrumentation problems observed by NRC regional inspectors

    International Nuclear Information System (INIS)

    Dennis, N.A.; Kinneman, J.D.; Costello, F.M.; White, J.R.; Nimitz, R.L.

    1983-01-01

    Early dosimetry processor performance studies conducted between 1967 and 1979 by several different investigators indicated that a significant percentage of personnel dosimetry processors may not be performing with a reasonable degree of accuracy. Results of voluntary performance testing of US personnel dosimetry processors against the final Health Physics Society Standard, Criteria for Testing Personnel Dosimetry Performance by the University of Michigan for the Nuclear Regulatory Commission (NRC) will be summarized with emphasis on processor performance in radiation categories involving beta particles and beta particles and photon mixtures. The current status of the NRC's regulatory program for improved personnel dosimetry processing will be reviewed. The NRC is proposing amendments to its regulations, 10 CFR Part 20, that would require its licensees to utilize specified personnel dosimetry services from processors accredited by the National Voluntary Laboratory Accreditation Program of the National Bureau of Standards. Details of the development and schedule for implementation of the program will be highlighted. Finally, selected beta dosimetry and beta instrumentation problems observed by NRC Regional Staff during inspections of NRC licensed facilities will be discussed

  20. The ICESat-2 mission: design, status, applications and pre-launch performance assessments for monitoring cryopsheric changes

    Science.gov (United States)

    Neumann, T.; Markus, T.; Csatho, B. M.; Martino, A. J.

    2013-12-01

    use changes and ocean surface topography and more. This presentation will provide an overview and status of the ICESat-2 mission, elaborate on its expected elevation precision and accuracy, and present simulated ICESat-2 data based on an airborne ICESat-2 simulator - the Multiple Altimeter Beam Experimental Lidar (MABEL).

  1. Current status and trends in performance-based risk-sharing arrangements between healthcare payers and medical product manufacturers.

    Science.gov (United States)

    Carlson, Josh J; Gries, Katharine S; Yeung, Kai; Sullivan, Sean D; Garrison, Louis P

    2014-06-01

    Our objective was to identify and characterize publicly available cases and related trends for performance-based risk-sharing arrangements (PBRSAs). We performed a review of PBRSAs over the past 20 years (1993-2013) using available databases and reports from colleagues and healthcare experts. These were categorized according to a previously published taxonomy of scheme types and assessed in terms of the underlying product and market attributes for each scheme. Macro-level trends were identified related to the timing of scheme adoption, countries involved, types of arrangements, and product and market factors. Our search yielded 148 arrangements. From this set, 65 arrangements included a coverage with an evidence development component, 20 included a conditional treatment continuation component, 54 included a performance-linked reimbursement component, and 42 included a financial utilization component. Each type of scheme addresses fundamental uncertainties that exist when products enter the market. The pace of adoption appears to be slowing, but new countries continue to implement PBRSAs. Over this 20-year period, there has been a consistent movement toward arrangements that minimize administrative burden. In conclusion, the pace of PBRSA adoption appears to be slowing but still has traction in many health systems. These remain a viable coverage and reimbursement mechanism for a wide range of medical products. The long-term viability and growth of these arrangements will rest in the ability of the parties to develop mutually beneficial arrangements that entail minimal administrative burden in their development and implementation.

  2. Effects of feed supplemented with fermented pine needles (Pinus ponderosa) on growth performance and antioxidant status in broilers.

    Science.gov (United States)

    Wu, Q J; Wang, Z B; Wang, G Y; Li, Y X; Qi, Y X

    2015-06-01

    The objective of this study was to compare the effects of Aspergillus niger-fermented pine needles and nonfermented pine needles on growth performance and antioxidant capacity in broiler chicks. In total, 300 1-day-old broiler chicks were randomly allocated to 5 dietary treatments, which were then denoted as the control treatment (basal diet); the nonfermented treatment (containing 0.3% and 0.6% nonfermented treatment, respectively, in the starter and grower phase); or the fermented 1, fermented 2, or fermented 3 treatments. The fermented 1, fermented 2, and fermented 3 treatments contained 0.1, 0.3, and 0.5% fermented treatment, respectively, in the starter phase and 0.2, 0.6, and 1.0% fermented treatment, respectively, in the growth phase for 42 d. The results showed that fermentation treated supplementation had no adverse effect on the growth performance of broilers at 42 d of age. The activity of total nitric oxide synthase was significantly (P<0.05) decreased in the fermented treatment compared with the control and nonfermented treatments in broilers at 21 d of age. Compared with the control, broilers had higher (P<0.05) total superoxide dismutase activities and total antioxidant capacity when they were provided with either the fermented 2 or fermented 3 diet. The malondialdehyde content was significantly (P<0.05) decreased in the fermented 2 and fermented 3 treatments compared with the control and nonfermented treatments. It was concluded that the addition of fermented treatment to the diet could improve antioxidant capacity in broilers, as evidenced by the decrease in malondialdehyde and the increase in total superoxide dismutase activities; however, the effect of fermentation treatment on growth performance was negligible. © 2015 Poultry Science Association Inc.

  3. No influence of smoking status on the performance of urine markers for the detection of bladder cancer.

    Science.gov (United States)

    Deininger, Susanne; Hennenlotter, J; Rausch, S; Docktor, K; Neumann, E; da Costa, I A; Bedke, J; Stenzl, A; Todenhöfer, T

    2018-04-19

    The performance of urinary markers for detecting bladder cancer (BC) is influenced by various factors. The aim of the present study was to evaluate the influence of smoking habits on the performance of four commonly used urine markers. Urine samples of 723 patients with suspected BC were analysed using urine cytology, fluorescence in situ hybridization (FISH), immunocytology (uCyt+ test), and quantitative nuclear matrix protein 22 (NMP22) immunoassay. The smoking habits of all patients were recorded and a cystoscopy performed within 2 weeks after urinary marker testing. Rates of false negative and false positive results were compared between non-smokers, former smokers, and current smokers by contingency analyses. We included 723 patients in this study, 431 (59.6%) of which were non-smokers, 215 former smokers (29.7%), and 77 (10.7%) current smokers. 148 patients (20.5%) had a tumour at the time of urinary marker testing. Respective rates of false positive test results among non-smokers, former smokers, and current smokers were: 16.3, 19.1, and 11.5% (p = 0.81) for urine cytology; 36.8, 42.0, and 32.7% for the uCyt+ test (p = 0.88); 18.0, 19.1, and 13.5% for FISH (p = 0.66); and 69.5, 71.6, and 71.2% for NMP22 (p = 0.67). Respective rates of false negatives among non-smokers, former smokers, and current smokers were: 31.4, 15.1, and 28.0% for cytology (p = 0.34); 21.4, 22.6, and 16.0% for uCyt+ test (p = 0.67); 24.3, 13.2, and 28.0% for FISH (p = 0.88); and 10.0, 18.9, and 8.0% for NMP22 (p = 0.80). Our results strongly suggest that smoking habits do not affect performance characteristics of urinary markers in the diagnostics of BC.

  4. Slow recovery of blood glucose in the insulin tolerance test during the prepartum transition period negatively impacts the nutritional status and reproductive performance postpartum of dairy cows.

    Science.gov (United States)

    Lee, Hsu-Hsun; Kida, Katsuya; Miura, Ryotaro; Inokuma, Hisashi; Miyamoto, Akio; Kawashima, Chiho; Haneda, Shingo; Miyake, Yoh-Ichi; Matsui, Motozumi

    2012-04-01

    In peripartum dairy cows, insulin resistance (IR) increases to adjust the direction of energy to lactation after calving. To investigate the effect of prepartum IR on postpartum reproductive performance, the insulin tolerance test (ITT) was applied to 15 cows at 3 weeks (Pre21) and 10 days (Pre10) before the predicted calving date. Blood glucose area under the curve (AUC(glu)) within 120 min after administration of 0.05 IU/kg-BW insulin was calculated. The occurrence of first ovulation, days to first artificial insemination (AI) and first AI conception rate were recorded. Nutritional status postpartum was evaluated by blood chemical analysis. Based on AUC(glu) changes from Pre21 to Pre10, cows were classified into either the AUC-up group (AUC(glu) increase, n=5) or the AUC-down group (AUC(glu) decrease, n=10). There was no difference in the decrease in blood glucose at 30 min after insulin injection between groups, although glucose recovery from 30 to 60 min during the ITT was slow at Pre10 in the AUC-up group. The AUC-up group had a higher number of days to first AI and high glucose, total protein, globulin, γ-glutamyltransferase, triacylglycerol levels and a low albumin-globulin ratio at the 14th day postpartum. The present study infers that prepartum slow glucose recovery rather than insulin sensitivity might increase the potential for subclinical health problems postpartum and thus suppress reproductive performance. During the prepartum transition period, glucose dynamics in the ITT can be considered as a new indicator for the postpartum metabolic status and reproductive performance of dairy cows.

  5. Effects of dietary organic chromium and vitamin C supplementation on performance, immune responses, blood metabolites, and stress status of laying hens subjected to high stocking density.

    Science.gov (United States)

    Mirfendereski, E; Jahanian, R

    2015-02-01

    The present study was carried out to investigate the effects of dietary supplementation of chromium-methionine (CrMet) and vitamin C (VC) on performance, immune response, and stress status of laying hens subjected to high stocking density. A total of 360 Hy-Line W-36 leghorn hens (at 26 wk old) were used in a 2×3×2 factorial arrangement that had 2 cage densities (5 and 7 hens per cage), 3 Cr levels (0, 500, and 1,000 ppb as CrMet), and 2 dietary VC levels (0 and 500 ppm as L-ascorbic acid). The trial lasted for 12 wk. The first 2 wk were for adaptation (26 to 28 wk of age), and the remaining 10 wk served as the main recording period. In addition to performance, immune response to Newcastle disease virus (NDV) was assessed at d 7 and 14 postvaccination. Also, the birds' stress status was evaluated by analyzing appropriate plasma metabolites. The results showed that hens in cages with higher stocking density had lower hen-day egg production, egg mass, and feed intake compared with those in normal density cages (Pfeed conversion efficiency (Pfeed conversion ratio in VC-unsupplemented diets. Although plasma concentrations of triglycerides and high-density lipoproteins were not influenced by dietary treatments, supplemental CrMet decreased plasma cholesterol levels (Phens kept at a density of 7 hens/cage were significantly higher than those of hens in normal cage density (Phens. While high stocking density caused a marked increase in plasma corticosterone (Phens. The high stocking density challenge suppressed NDV antibody response (Phens kept at a density of 7 hens/cage (P<0.01). From the present observations, it can be concluded that CrMet can improve laying performance largely because it alleviates harmful responses to stressful conditions. © 2015 Poultry Science Association Inc.

  6. Dietary acid load and renal function have varying effects on blood acid-base status and exercise performance across age and sex.

    Science.gov (United States)

    Hietavala, Enni-Maria; Stout, Jeffrey R; Frassetto, Lynda A; Puurtinen, Risto; Pitkänen, Hannu; Selänne, Harri; Suominen, Harri; Mero, Antti A

    2017-12-01

    Diet composition influences acid-base status of the body. This may become more relevant as renal functional capacity declines with aging. We examined the effects of low (LD) versus high dietary acid load (HD) on blood acid-base status and exercise performance. Participants included 22 adolescents, 33 young adults (YA), and 33 elderly (EL), who followed a 7-day LD and HD in a randomized order. At the end of both diet periods the subjects performed a cycle ergometer test (3 × 10 min at 35%, 55%, 75%, and (except EL) until exhaustion at 100% of maximal oxygen uptake). At the beginning of and after the diet periods, blood samples were collected at rest and after all workloads. Oxygen uptake, respiratory exchange ratio (RER), and heart rate (HR) were monitored during cycling. In YA and EL, bicarbonate (HCO 3 - ) and base excess (BE) decreased over the HD period, and HCO 3 - , BE, and pH were lower at rest after HD compared with LD. In YA and EL women, HCO 3 - and BE were lower at submaximal workloads after HD compared with LD. In YA women, the maximal workload was 19% shorter and maximal oxygen uptake, RER, and HR were lower after HD compared with LD. Our data uniquely suggests that better renal function is associated with higher availability of bases, which may diminish exercise-induced acidosis and improve maximal aerobic performance. Differences in glomerular filtration rate between the subject groups likely explains the larger effects of dietary acid load in the elderly compared with younger subjects and in women compared with men.

  7. FY16 Status of Immersion Phased Array Ultrasonic Probe Development and Performance Demonstration Results for Under Sodium Viewing

    International Nuclear Information System (INIS)

    Diaz, Aaron A.; Chamberlin, Clyde E.; Edwards, Matthew K.; Hagge, Tobias J.; Hughes, Michael S.; Larche, Michael R.; Mathews, Royce A.; Neill, Kevin J.; Prowant, Matthew S.

    2016-01-01

    This section of the Joint summary technical letter report (TLR) describes work conducted at the Pacific Northwest National Laboratory (PNNL) during FY 2016 (FY16) on the under-sodium viewing (USV) PNNL project 58745, work package AT-16PN230102. This section of the TLR satisfies PNNL's M3AT-16PN2301025 milestone and is focused on summarizing the design, development, and evaluation of two different phased-array ultrasonic testing (PA-UT) probe designs - a two-dimensional (2D) matrix phased-array probe, and two one-dimensional (1D) linear array probes, referred to as serial number 4 (SN4) engineering test units (ETUs). The 2D probe is a pulse-echo (PE), 32x2, 64-element matrix phased-array ETU. The 1D probes are 32x1 element linear array ETUs. This TLR also provides the results from a performance demonstration (PD) of in-sodium target detection trials at 260°C using both probe designs. This effort continues the iterative evolution supporting the longer term goal of producing and demonstrating a pre-manufacturing prototype ultrasonic probe that possesses the fundamental performance characteristics necessary to enable the development of a high-temperature sodium-cooled fast reactor (SFR) inspection system for in-sodium detection and imaging.

  8. FY16 Status of Immersion Phased Array Ultrasonic Probe Development and Performance Demonstration Results for Under Sodium Viewing

    Energy Technology Data Exchange (ETDEWEB)

    Diaz, Aaron A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Chamberlin, Clyde E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Edwards, Matthew K. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hagge, Tobias J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hughes, Michael S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Larche, Michael R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Mathews, Royce A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Neill, Kevin J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Prowant, Matthew S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-08-31

    This section of the Joint summary technical letter report (TLR) describes work conducted at the Pacific Northwest National Laboratory (PNNL) during FY 2016 (FY16) on the under-sodium viewing (USV) PNNL project 58745, work package AT-16PN230102. This section of the TLR satisfies PNNL’s M3AT-16PN2301025 milestone and is focused on summarizing the design, development, and evaluation of two different phased-array ultrasonic testing (PA-UT) probe designs—a two-dimensional (2D) matrix phased-array probe, and two one-dimensional (1D) linear array probes, referred to as serial number 4 (SN4) engineering test units (ETUs). The 2D probe is a pulse-echo (PE), 32×2, 64-element matrix phased-array ETU. The 1D probes are 32×1 element linear array ETUs. This TLR also provides the results from a performance demonstration (PD) of in-sodium target detection trials at 260°C using both probe designs. This effort continues the iterative evolution supporting the longer term goal of producing and demonstrating a pre-manufacturing prototype ultrasonic probe that possesses the fundamental performance characteristics necessary to enable the development of a high-temperature sodium-cooled fast reactor (SFR) inspection system for in-sodium detection and imaging.

  9. The Jules Horowitz Reactor - A new High Performance European Material Testing Reactor open to International Users Present Status and Objectives

    International Nuclear Information System (INIS)

    Iracane, Daniel; Bignan, Gilles; Lindbaeck, Jan-Erik; Blomgren, Jan

    2010-01-01

    The development of sustainable nuclear energy requires R and D on fuel and material behaviour under irradiation with a high level of performance in order to meet the needs and challenges for the benefit of industry, research and public bodies. These stakes require a sustainable and secured access to an up-to-date high performance Material Testing Reactor. Following a broad survey within the European Research Area, the international community agreed that the need for Material Test Reactors in support of nuclear power plant safety and operation will continue in the context of sustainable nuclear energy. The Jules Horowitz Reactor project (JHR) copes with this context. JHR is designed as a user facility addressing the needs of the international community. This means: - flexibility with irradiation loops able to reproduce a large variation in operation conditions of different power reactor technologies, - high flux capacity to address Generations II, III, and IV needs. JHR is designed, built and operated as an international user facility because: - Given the maturity and globalization of the industry, domestic tools have no more the required level of economic and technical efficiency. Meanwhile, countries with nuclear energy need an access to high performance irradiation experimental capabilities to support technical skill and guarantee the competitiveness and safety of nuclear energy. - Many research items related to safety or public policy (waste management, etc.) require international cooperation to share costs and benefits of resulting consensus. JHR design is optimised for offering high performance material and fuel irradiation capability for the coming decades. This project is driven and funded by an international consortium gathering vendors, utilities and public stakeholders. This consortium has been set up in March 2007 when the construction began. The construction is in progress and the start of operation is scheduled for 2014. The JHR is a research

  10. A study of the academic performance of medical students in the comprehensive examination of the basic sciences according to the indices of emotional intelligence and educational status.

    Science.gov (United States)

    Moslehi, Mohsen; Samouei, Rahele; Tayebani, Tayebeh; Kolahduz, Sima

    2015-01-01

    Considering the increasing importance of emotional intelligence (EI) in different aspects of life, such as academic achievement, the present survey is aimed to predict academic performance of medical students in the comprehensive examination of the basic sciences, according to the indices of emotional intelligence and educational status. The present survey is a descriptive, analytical, and cross-sectional study performed on the medical students of Isfahan, Tehran, and Mashhad Universities of Medical Sciences. Sampling the universities was performed randomly after which selecting the students was done, taking into consideration the limitation in their numbers. Based on the inclusion criteria, all the medical students, entrance of 2005, who had attended the comprehensive basic sciences examination in 2008, entered the study. The data collection tools included an Emotional Intelligence Questionnaire (standardized in Isfahan), the average score of the first to fifth semesters, total average of each of the five semesters, and the grade of the comprehensive basic sciences examination. The data were analyzed through stepwise regression coefficient by SPSS software version 15. The results indicated that the indicators of independence from an emotional intelligence test and average scores of the first and third academic semesters were significant in predicting the students' academic performance in the comprehensive basic sciences examination. According to the obtained results, the average scores of students, especially in the earlier semesters, as well as the indicators of independence and the self-esteem rate of students can influence their success in the comprehensive basic sciences examination.

  11. A Review on the Role of Chromium Supplementation in Ruminant Nutrition-Effects on Productive Performance, Blood Metabolites, Antioxidant Status, and Immunocompetence.

    Science.gov (United States)

    Lashkari, Saman; Habibian, Mahmood; Jensen, Søren Krogh

    2018-03-28

    With the increase in the global herd, the use of metabolic modifiers has become an important area for many researchers looking for a supraphysiological diet to improve production parameters. For improving the performance of high yielding cows, the optimal balance of all nutrients including microminerals is important. Chromium (Cr) is one of the important micronutrients which plays an important role in metabolism of ruminants. Experimental studies have found that Cr could change performance, immune responses, glucose and fatty acid metabolism, and antioxidant status in dairy cows. In some studies, Cr supplementation improved dry matter intake, milk production, and milk composition of dairy cows in the early, mid, or late stage of lactation. Also, in some studies, performance of growing animal, immune response, and some blood parameters responded positively to Cr supplementation. In conclusion, the effects of Cr supplementation on performance of ruminants are inconsistent; however, its long-term effects on health, productivity, immune system, and antioxidant activity of ruminants still need to be investigated.

  12. A study of the academic performance of medical students in the comprehensive examination of the basic sciences according to the indices of emotional intelligence and educational status

    Science.gov (United States)

    Moslehi, Mohsen; Samouei, Rahele; Tayebani, Tayebeh; Kolahduz, Sima

    2015-01-01

    Background: Considering the increasing importance of emotional intelligence (EI) in different aspects of life, such as academic achievement, the present survey is aimed to predict academic performance of medical students in the comprehensive examination of the basic sciences, according to the indices of emotional intelligence and educational status. Materials and Methods: The present survey is a descriptive, analytical, and cross-sectional study performed on the medical students of Isfahan, Tehran, and Mashhad Universities of Medical Sciences. Sampling the universities was performed randomly after which selecting the students was done, taking into consideration the limitation in their numbers. Based on the inclusion criteria, all the medical students, entrance of 2005, who had attended the comprehensive basic sciences examination in 2008, entered the study. The data collection tools included an Emotional Intelligence Questionnaire (standardized in Isfahan), the average score of the first to fifth semesters, total average of each of the five semesters, and the grade of the comprehensive basic sciences examination. The data were analyzed through stepwise regression coefficient by SPSS software version 15. Results: The results indicated that the indicators of independence from an emotional intelligence test and average scores of the first and third academic semesters were significant in predicting the students’ academic performance in the comprehensive basic sciences examination. Conclusion: According to the obtained results, the average scores of students, especially in the earlier semesters, as well as the indicators of independence and the self-esteem rate of students can influence their success in the comprehensive basic sciences examination. PMID:26430693

  13. Status of the Atlas Calorimeters: their performance during three years of LHC operation and plans for future upgrades.

    CERN Document Server

    Majewski, S; The ATLAS collaboration

    2014-01-01

    The ATLAS experiment is designed to study the proton-proton collisions produced at the Large Hadron Collider (LHC) at CERN. Its calorimeter system measures the energy and direction of final state particles over the pseudorapidity range $|\\eta| < 4.9$. Accurate identification and measurement of the characteristics of electromagnetic objects (electrons/photons) are performed by liquid argon (LAr)-lead sampling calorimeters in the region $|\\eta| < 3.2$, using an innovative accordion geometry that provides a fast, uniform response without azimuthal gaps. This system played a critical role in the ATLAS analyses contributing to the Higgs boson discovery announced in 2012. The hadronic calorimeters measure the properties of hadrons, jets, and tau leptons, and also contribute to the measurement of the missing transverse energy and the identification of muons. A scintillator-steel sampling calorimeter (TileCal) is employed in the region $|\\eta| < 1.7$, while the region $1.5 < |\\eta| < 3.2$ is covered wi...

  14. Status of the Atlas Calorimeters: their performance after two years of LHC operation and plans for future upgrades

    CERN Document Server

    Solans, CA; The ATLAS collaboration

    2012-01-01

    The ATLAS experiment is designed to study the proton-proton collisions produced at the Large Hadron Collider (LHC) at CERN. Its calorimeter system measures the energy and direction of final state particles with pseudo rapidity $|eta| < 4.9$. Accurate identification and measurement of the characteristics of electromagnetic objects (electrons/photons) are performed by liquid argon (LAr)-lead sampling calorimeters in the region $|eta| < 3.2$, using an innovative accordion geometry that provides a fast, uniform azimuthal response without gaps. The hadronic calorimeters measure the properties of hadrons, jets, and tau leptons, and also contribute to the measurement of the missing transverse energy and identification of muons. This is done in the region $|eta| < 1.7$ with a scintillator-steel sampling calorimeter, and in the region $1.4 < |eta| < 3.2$ with a copper-LAr sampling calorimeter. The coverage is extended to $|eta| < 4.9$ by an integrated forward calorimeter (FCal...

  15. FY15 Status of Immersion Phased Array Ultrasonic Probe Development and Performance Demonstration Results for Under Sodium Viewing

    Energy Technology Data Exchange (ETDEWEB)

    Diaz, Aaron A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Larche, Michael R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Mathews, Royce [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Neill, Kevin J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Baldwin, David L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Prowant, Matthew S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Edwards, Matthew K. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Chamberlin, Clyde E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-09-01

    This Technical Letter Report (TLR) describes work conducted at the Pacific Northwest National Laboratory (PNNL) during FY 2015 on the under-sodium viewing (USV) PNNL project 58745, Work Package AT-15PN230102. This TLR satisfies PNNL’s M3AT-15PN2301027 milestone, and is focused on summarizing the design, development, and evaluation of a two-dimensional matrix phased-array probe referred to as serial number 3 (SN3). In addition, this TLR also provides the results from a performance demonstration of in-sodium target detection trials at 260°C using a one-dimensional 22-element linear array developed in FY14 and referred to as serial number 2 (SN2).

  16. The influence of genital tract status in postpartum period on the subsequent reproductive performance in high producing dairy cows.

    Science.gov (United States)

    López-Helguera, I; López-Gatius, F; Garcia-Ispierto, I

    2012-04-15

    The aim of the present study was to characterize the early postpartum period in clinically healthy dairy cows by ultrasonography (US), endometrial cytology (EC), and white blood cell counts, and determine possible relationships between postpartum findings and subsequent reproductive performance. Fifty-three dairy cows were examined on Days 15 to 21 (Visit 1), 22 to 28 (Visit 2), and 29 to 35 (Visit 3) postpartum. The clinical examination included: examination of vaginal fluid, EC, transrectal palpation and ultrasonography of the genital tract (cervical diameter, endometrial thickness, presence of a corpus luteum [CL] or intrauterine fluid [IUF] and its echogenicity). Luteal activity (presence of a CL in a single visit), return to cyclicity (presence of a CL in 2 consecutive visits), and conception rate at 70 and 120 days postpartum were considered as the dependent variables in four consecutive binary logistic regression analyses. Factors affecting leukocyte counts were established by general linear model (GLM) repeated measures analysis of variance. Based on the odds ratio (OR), the likelihood of luteal activity was higher in multiparous than primiparous cows (OR = 3.75) and tended to diminish in cows showing increased endometrial thickness in Visit 1 (V1) (OR = 0.06). The likelihood of returning to cyclicity decreased for each centimeter increase in cervical diameter in V1 (OR = 0.14) and that of conception on Day 70 was lower in cows showing the presence of echogenic or anechogenic IUF in V1 (OR = 0.09 or OR = 0.13, respectively) compared with cows lacking IUF. Effects of parity and IUF were observed on neutrophil counts. Positive EC results were unrelated to the cumulative conception rate at 70 and 120 days in milk, whereas cows returning a positive EC result in V1 showed a greater likelihood of increased endometrial thickness. In conclusion, measuring cervical diameter, endometrial thickness, and detecting the echogenicity of IUF by ultrasonography from Days 15

  17. Leptin status in adolescence is associated with academic performance in high school: a cross-sectional study in a Chilean birth cohort.

    Science.gov (United States)

    Correa-Burrows, Paulina; Blanco, Estela; Reyes, Marcela; Castillo, Marcela; Peirano, Patricio; Algarín, Cecilia; Lozoff, Betsy; Gahagan, Sheila; Burrows, Raquel

    2016-10-18

    Leptin is a pleiotropic hormone associated with learning and memory via brain receptors. However, elevated plasma leptin levels may impair cognitive and memory functions. Since individual differences in memory performance affect students' ability to learn, we aimed to study the relation between leptin status in adolescence and school performance. We studied 568 adolescents aged 16-17 years from Santiago. A cross-sectional analysis was carried out on a birth cohort conducted in Santiago (Chile). We measured serum leptin concentration using an enzyme-linked immunosorbent assay. Cut-offs from the Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) Study for 16-year-olds were used to define abnormally high leptin levels (hyperleptinaemia). Academic performance was measured using high-school grades and grade point average (GPA). Data were collected in 2009-2012; data analysis was performed in 2014. 15% of participants had hyperleptinaemia. They had significantly lower school grades and GPA compared with participants with normal leptin levels (eg, GPA mean difference=33.8 points). Leptin levels were negative and significantly correlated with school grades in 9th, 10th and 12th. Similarly, it was negatively correlated with high-school GPA. After controlling for health, sociodemographic and education confounders, the chances of having a performance ≥75th centile in students having hyperleptinaemia were 32% (95% CI 0.19% to 0.89%) that of students having normal serum leptin concentration. In high school students, abnormally high levels of leptin were associated with poorer academic performance. These findings support the idea of a relationship between leptin and cognition. Further research is needed on the cognitive effects of leptin in younger populations. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  18. Effectiveness of braille and audio-tactile performance technique for improving oral hygiene status of visually impaired adolescents.

    Science.gov (United States)

    Deshpande, Sushmita; Rajpurohit, Ladusingh; Kokka, Vivian Varghese

    2017-01-01

    Visually impaired people encounter numerous challenges in their daily life which makes it a cumbersome task to pay special attention to oral health needs. Furthermore, there is little knowledge about oral health practices among caretakers and visually impaired individuals, due to which oral health is often neglected when compared to the general health. Hence, there was a need to educate visually challenged individuals about oral hygiene practices in a customized format so that the comprehension of brushing techniques could be conveyed at its best. The present study was a randomized control trial of sixty visually impaired adolescents who were divided into three groups of 20 each. In Group 1, Braille was used, whereas in Group 2, audio-tactile performance (ATP) technique and in Group 3, a combination of both the methods were used to teach tooth brushing as a part of oral health education. Pre- and post-plaque index score using Silness and Loe (1967) after health education were calculated and tabulated for statistical analysis. The postintervention mean plaque index score increased in Group 1 from 29.45 to 42.98, whereas the mean plaque score decreased in Groups 2 and 3 from 30.83-29.9 to 30.23-18.73, respectively. Intergroup comparison of postplaque index score using Kruskal-Wallis and ANOVA analysis showed significant difference among all three study groups. The combination of Braille and ATP technique of health education served as the most effective medium to teach oral hygiene methods to visually impaired adolescents.

  19. Status of the Atlas Calorimeters: their performance after two years of LHC operation and plans for future upgrades.

    CERN Document Server

    Solans, C; The ATLAS collaboration

    2012-01-01

    The ATLAS experiment is designed to study the proton-proton collisions produced at the Large Hadron Collider (LHC) at CERN. Its calorimeter system measures the energy and direction of final state particles with pseudo rapidity $|eta| < 4.9$. Accurate identification and measurement of the characteristics of electromagnetic objects (electrons/photons) are performed by liquid argon (LAr)-lead sampling calorimeters in the region $|eta| < 3.2$, using an innovative accordion geometry that provides a fast, uniform azimuthal response without gaps. The hadronic calorimeters measure the properties of hadrons, jets, and tau leptons, and also contribute to the measurement of the missing transverse energy and identification of muons. This is done in the region $|eta| < 1.7$ with a scintillator-steel sampling calorimeter, and in the region $1.4 < |eta| < 3.2$ with a copper-LAr sampling calorimeter. The coverage is extended to $|eta| < 4.9$ by an integrated forward calorimeter (FCal) based on LAr with copp...

  20. The Jules Horowitz reactor, a new high performance European material testing reactor open to international users: present status and objectives

    International Nuclear Information System (INIS)

    Iracane, D.; Bignan, G.

    2010-01-01

    The development of nuclear power as a sustainable and competitive energy source will continue to require research and development of fuel and material behaviour under irradiation. This necessitates a high performance material testing reactor (MTR). Facing the obsolescence of most of the existing MTR in Europe, France decided a few years ago the construction of the RJH (Jules Horowitz reactor). RJH is designed, built and will be operated as an international user facility. A first set of experimental hosting devices is being designed. For instance, there are the in-core CALIPSO Nak integrated loop for material studies and other loops for fuel studies under nominal or off-normal or accidental conditions. The RJH international program will focus on the following subjects: -) fuel reliability, assessed through power ramps tests and post-irradiation examination; -) Loss of coolant tests done out-of-pile in a first phase and in-pile in a possible second phase; and -) source term tests addressing fission products release. The paper reports also the point of view of VATTENFALL (a Swedish power utility), as a potential European RJH user. (A.C.)

  1. Randomized phase II study of gefitinib compared with placebo in chemotherapy-naive patients with advanced non-small-cell lung cancer and poor performance status.

    Science.gov (United States)

    Goss, Glenwood; Ferry, David; Wierzbicki, Rafal; Laurie, Scott A; Thompson, Joyce; Biesma, Bonne; Hirsch, Fred R; Varella-Garcia, Marileila; Duffield, Emma; Ataman, Ozlem U; Zarenda, Marc; Armour, Alison A

    2009-05-01

    To compare gefitinib with placebo in chemotherapy naïve patients with advanced non-small-cell lung cancer (NSCLC) and poor performance status. NSCLC patients (chemotherapy naïve, WHO performance status 2 or 3; unfit for chemotherapy; stage IIIB/IV) were randomly assigned to gefitinib (250 mg/d) plus best supportive care (BSC; n = 100) or placebo plus BSC (n = 101). The primary end point was progression-free survival (PFS). Secondary end points included overall survival (OS), objective response rate (ORR), quality of life (QOL), pulmonary symptom improvement (PSI), and safety. Correlation of gefitinib efficacy with EGFR gene copy number (fluorescent in situ hybridization [FISH]) was explored. Hazard ratios (HRs; gefitinib:placebo) were 0.82 (95% CI, 0.60 to 1.12; P = .217) for PFS and 0.84 (95% CI, 0.62 to 1.15; P = .272) for OS. As expected for this patient population, OS for both arms was poor, at about 3 months. ORRs were 6.0% (gefitinib) and 1.0% (placebo). QOL and PSI rates were 21.1% and 28.3% (gefitinib) and 20.0% and 28.3% (placebo), respectively. In EGFR FISH-positive patients (n = 32), HRs were 0.29 (95% CI, 0.11 to 0.73) for PFS and 0.44 (95% CI, 0.17 to 1.12) for OS. No unexpected adverse events occurred. There was no statistically significant difference in PFS, OS, and ORRs after treatment with gefitinib or placebo, in the overall population; improvements in QOL and symptoms were similar in both groups. Tolerability profile of gefitinib was consistent with previous studies. PFS was statistically significantly improved for gefitinib-treated patients with EGFR FISH-positive tumors.

  2. Randomized Phase II Study of Gefitinib Compared With Placebo in Chemotherapy-Naive Patients With Advanced Non–Small-Cell Lung Cancer and Poor Performance Status

    Science.gov (United States)

    Goss, Glenwood; Ferry, David; Wierzbicki, Rafal; Laurie, Scott A.; Thompson, Joyce; Biesma, Bonne; Hirsch, Fred R.; Varella-Garcia, Marileila; Duffield, Emma; Ataman, Ozlem U.; Zarenda, Marc; Armour, Alison A.

    2009-01-01

    Purpose To compare gefitinib with placebo in chemotherapy naïve patients with advanced non–small-cell lung cancer (NSCLC) and poor performance status. Patients and Methods NSCLC patients (chemotherapy naïve, WHO performance status 2 or 3; unfit for chemotherapy; stage IIIB/IV) were randomly assigned to gefitinib (250 mg/d) plus best supportive care (BSC; n = 100) or placebo plus BSC (n = 101). The primary end point was progression-free survival (PFS). Secondary end points included overall survival (OS), objective response rate (ORR), quality of life (QOL), pulmonary symptom improvement (PSI), and safety. Correlation of gefitinib efficacy with EGFR gene copy number (fluorescent in situ hybridization [FISH]) was explored. Results Hazard ratios (HRs; gefitinib:placebo) were 0.82 (95% CI, 0.60 to 1.12; P = .217) for PFS and 0.84 (95% CI, 0.62 to 1.15; P = .272) for OS. As expected for this patient population, OS for both arms was poor, at about 3 months. ORRs were 6.0% (gefitinib) and 1.0% (placebo). QOL and PSI rates were 21.1% and 28.3% (gefitinib) and 20.0% and 28.3% (placebo), respectively. In EGFR FISH-positive patients (n = 32), HRs were 0.29 (95% CI, 0.11 to 0.73) for PFS and 0.44 (95% CI, 0.17 to 1.12) for OS. No unexpected adverse events occurred. Conclusion There was no statistically significant difference in PFS, OS, and ORRs after treatment with gefitinib or placebo, in the overall population; improvements in QOL and symptoms were similar in both groups. Tolerability profile of gefitinib was consistent with previous studies. PFS was statistically significantly improved for gefitinib-treated patients with EGFR FISH-positive tumors. PMID:19289623

  3. The effects of partial replacement of soybean meal by xylose-treated soybean meal in the starter concentrate on performance, health status, and blood metabolites of Holstein calves

    Directory of Open Access Journals (Sweden)

    Mehdi Kazemi-Bonchenari

    2015-04-01

    Full Text Available The objective was to study the effects of partial replacement of soybean meal (SBM with xylose-treated SBM (XSBM as a source of rumen undegradable protein (RUP in the starter concentrate of calves on performance, health status and selected blood metabolites. Twenty-one female Holstein dairy calves (body weight=39.6±2.3 kg were randomly assigned to 3 groups (n=7 each: i starter concentrate with 25% SBM [control (CTR]; ii starter concentrate with 17.5% SBM +7.5% XSBM (7.5XSBM; and iii starter concentrate with 12.5% SBM+12.5% XSBM (12.5XSBM. Calves received 2 L of milk twice daily, with ad libitum access to starter concentrates from d 4 until weaning (d 56. Performance and health status were recorded throughout the experiment. Blood samples collected on d 4, 35 and 56 were assayed for concentrations of glucose, total protein (TP, and plasma urea nitrogen (PUN. Starter intake (560, 400, and 420 g/d for CTR, 7.5XSBM, and 12.5XSBM, respectively, average daily gain (0.67, 0.6 and 0.57 kg/d, and feed to gain ratio (0.83, 0.67, and 0.74 were affected by treatments (P<0.05. Hearth girth, height at withers, body length, rectal temperature, faecal score, and respiratory score did not differ among treatments. Mean plasma glucose and TP were not affected by treatments, whereas PUN in the 12.5XSBM group was lower than in the other groups (P<0.05. In conclusion, the present results showed that partial replacement of SBM by XSBM may improve efficiency of dietary protein utilisation in pre-weaned calves, which warrants further studies.

  4. Feeding glycerol-enriched yeast culture improves performance, energy status, and heat shock protein gene expression of lactating Holstein cows under heat stress.

    Science.gov (United States)

    Liu, J; Ye, G; Zhou, Y; Liu, Y; Zhao, L; Liu, Y; Chen, X; Huang, D; Liao, S F; Huang, K

    2014-06-01

    This study was conducted to evaluate the effects of supplemental common yeast culture (CY) and glycerol-enriched yeast culture (GY) on performance, plasma metabolites, antioxidant status, and heat shock protein 70 (HSP70) mRNA expression in lactating Holstein cows under heat stress. During summer months, 30 healthy multiparous lactating cows (parity 3.25 ± 0.48; 60 ± 13 d in milk [DIM]; 648 ± 57 kg BW; an average milk yield of 33.8 ± 1.6 kg/d) were blocked by parity, previous milk yield, and DIM and randomly allocated to 3 dietary treatments: no supplemental yeast culture (Control), 1 L/d of CY (33.1 g yeast) per cow, and 2 L/d of GY (153.2 g glycerol and 31.6 g yeast) per cow. During the 60-d experiment, values of air temperature and relative humidity inside the barn were recorded hourly every 3 d to calculate temperature-humidity index (THI). Weekly rectal temperatures (RT) and respiration rates and daily DMI and milk yield were recorded for all cows. Milk and blood samples were taken twice monthly, and BW and BCS were obtained on d 0 and 60. In this experiment, THI values indicated cows experienced a moderate heat stress. Cows supplemented with CY and GY had greater yields of milk, energy-corrected milk and milk fat, and milk fat percent but lower HSP70 mRNA expression in peripheral blood lymphocytes than Control cows (P cows. In conclusion, either CY or GY supplementation partially mitigated the negative effects of heat stress on performance and HSP70 mRNA expression of lactating cows, and GY supplementation provided additional improvements in energy status and HSP70 gene expression of lactating cows.

  5. Current Status of the Transmutation Reactor Technology and Preliminary Evaluation of Transmutation Performance of the KALIMER Core

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Ser Gi; Sim, Yoon Sub; Kim, Yeong Il; Kim, Young Gyum; Lee, Byung Woon; Song, Hoon; Lee, Ki Bog; Jang, Jin Wook; Lee, Dong Uk

    2005-08-15

    devised. It has been considered that the degradations of core performances resulting from increase of the transmutation rate are very important problems. From the analysis results of the state-of-art of the nuclear transmutation technology, the following technical research topics are determined as the technical solution ways for the future development and enhancement of the transmutation technology; 1) the improvement of core safety through the reduction of the coolant void reactivity worth by using the void duct assembly, 2) the design of a reference transmutation reactor for the future transmutation research through the change of the KALIMER-600 reactor core into the transmutation reactor and its core performance analysis, 3) the optimization study of the hybrid loading of uranium-free fuel and uranium fuel to improve the transmutation rate and the core safety parameters. Finally, the feasibility of the transmutation core suggested above where the void duct assemblies are devised to improve the sodium void reactivity worth and to achieve the power flattening under a single fuel enrichment and a single type of fuel assembly is analyzed and assessed. The results show that this core has its sodium coolant void reactivity less than 3$ and this core can transmutate the TRU nuclides discharged from two LWRs of the same thermal power.

  6. Effectiveness of braille and audio-tactile performance technique for improving oral hygiene status of visually impaired adolescents

    Directory of Open Access Journals (Sweden)

    Sushmita Deshpande

    2017-01-01

    Full Text Available Background: Visually impaired people encounter numerous challenges in their daily life which makes it a cumbersome task to pay special attention to oral health needs. Furthermore, there is little knowledge about oral health practices among caretakers and visually impaired individuals, due to which oral health is often neglected when compared to the general health. Hence, there was a need to educate visually challenged individuals about oral hygiene practices in a customized format so that the comprehension of brushing techniques could be conveyed at its best. Materials and Methods: The present study was a randomized control trial of sixty visually impaired adolescents who were divided into three groups of 20 each. In Group 1, Braille was used, whereas in Group 2, audio-tactile performance (ATP technique and in Group 3, a combination of both the methods were used to teach tooth brushing as a part of oral health education. Pre- and post-plaque index score using Silness and Loe (1967 after health education were calculated and tabulated for statistical analysis. Results: The postintervention mean plaque index score increased in Group 1 from 29.45 to 42.98, whereas the mean plaque score decreased in Groups 2 and 3 from 30.83–29.9 to 30.23–18.73, respectively. Intergroup comparison of postplaque index score using Kruskal–Wallis and ANOVA analysis showed significant difference among all three study groups. Conclusion: The combination of Braille and ATP technique of health education served as the most effective medium to teach oral hygiene methods to visually impaired adolescents.

  7. Recent status of development and irradiation performance for plate type fuel elements with reduced 235U enrichment at NUKEM

    International Nuclear Information System (INIS)

    Hrovat, M.F.; Hassel, H.W.

    1984-01-01

    According to the present state of development full size test fuel elements with the maximum uranium densities of 2,2 g U/cm 3 meat for UAlsub(x), 3,2 g U/cm 3 meat for U 3 O 8 and 4,8 g U/cm 3 meat for U 3 Si 2 can be fabricated at NUKEM in production scale. Special chemical procedures for the uranium recovery were developed ensuring an economic fuel fabrication process. The post irradiation examinations (PIE) of 12 UAlsub(x) (U density 2,2 g U/cm 3 meat) and U 3 O 8 (up to 3,1 g U/cm 3 meat) test plates irradiated in the ORR, Oak Ridge research reactor, were terminated. All 12 test plates show unobjectionable irradiation behavior. Extensive irradiation tests on full size fuel elements were performed. All inserted elements show perfect irradiation behavior. The PIE of the first HFR Petten U 3 O 8 fuel elements are in progress. The full size ORR U 3 Si 2 fuel elements with so far highest uranium density of 4,76 g U/cm 3 meat achieved a burnup of 50 % loss of 235 U up to May 1983. One element was withdrawn from the reactor for PIE, the second will be irradiated to a burnup of 75 % loss of 235 U. The further development is concentrated on Usub(x)Sisub(y) fuel with highest uranium density. U 3 Si miniplates with up to 6,1 g U/cm 3 meat are supplied meeting the required specification, U 3 Si miniplates with 6,7 g U/cm 3 are in fabrication. (author)

  8. The Effects of a Sports Nutrition Education Intervention on Nutritional Status, Sport Nutrition Knowledge, Body Composition, and Performance during Off Season Training in NCAA Division I Baseball Players

    Directory of Open Access Journals (Sweden)

    Fabrício Eduardo Rossi, Andrew Landreth, Stacey Beam, Taylor Jones, Layne Norton, Jason Michael Cholewa

    2017-03-01

    Full Text Available This study investigated the effects of a sport nutrition education intervention (SNEI on dietary intake, knowledge, body composition, and performance in NCAA Division I baseball players. Resistance trained NCAA Division I baseball players (82.4 ± 8.2 kg; 1.83 ± 0.06 m; 13.7 ± 5 % body fat participated in the study during 12 weeks of off-season training. Fifteen players volunteered for SNEI while 15 players matched for position served as controls (C for body composition and performance. The nutrition intervention group (NI received a 90 min SNEI encompassing energy intake (Kcal, carbohydrate (CHO, protein (PRO, fat, food sources, and hydration. Sport nutrition knowledge questionnaires were administered to NI pre and post. Nutritional status was determined by three-day dietary logs administered to NI pre and post. Body composition and performance (5-10-5 shuttle test, vertical jump, broad jump, 1 RM squat were measured pre and post for C and NI. Knowledge increased in NI. Pro and fat, but not CHO intake increased in NI. FM decreased pre to post in NI (11.5 ± 4.8 vs. 10.5 ± 5.4 kg but not C (11.3 ± 4.7 vs. 11.9 ± 4.5 kg. FFM increased pre to post with no differences between groups. The 5-10-5 shuttle times decreased significantly more in NI (4.58 ± 0.15 vs. 4.43 ± 0.13 sec compared to C (4.56 ± 0.18 vs. 4.50 ± 0.16 sec. Jump and squat performance increased pre to post with no differences between groups. Our findings indicate that an off season SNEI is effective at improving sport nutrition knowledge and some, but not all, nutrient intakes and performance measures in Division I baseball players.

  9. The Effects of a Sports Nutrition Education Intervention on Nutritional Status, Sport Nutrition Knowledge, Body Composition, and Performance during Off Season Training in NCAA Division I Baseball Players.

    Science.gov (United States)

    Rossi, Fabrício Eduardo; Landreth, Andrew; Beam, Stacey; Jones, Taylor; Norton, Layne; Cholewa, Jason Michael

    2017-03-01

    This study investigated the effects of a sport nutrition education intervention (SNEI) on dietary intake, knowledge, body composition, and performance in NCAA Division I baseball players. Resistance trained NCAA Division I baseball players (82.4 ± 8.2 kg; 1.83 ± 0.06 m; 13.7 ± 5 % body fat) participated in the study during 12 weeks of off-season training. Fifteen players volunteered for SNEI while 15 players matched for position served as controls (C) for body composition and performance. The nutrition intervention group (NI) received a 90 min SNEI encompassing energy intake (Kcal), carbohydrate (CHO), protein (PRO), fat, food sources, and hydration. Sport nutrition knowledge questionnaires were administered to NI pre and post. Nutritional status was determined by three-day dietary logs administered to NI pre and post. Body composition and performance (5-10-5 shuttle test, vertical jump, broad jump, 1 RM squat) were measured pre and post for C and NI. Knowledge increased in NI. Pro and fat, but not CHO intake increased in NI. FM decreased pre to post in NI (11.5 ± 4.8 vs. 10.5 ± 5.4 kg) but not C (11.3 ± 4.7 vs. 11.9 ± 4.5 kg). FFM increased pre to post with no differences between groups. The 5-10-5 shuttle times decreased significantly more in NI (4.58 ± 0.15 vs. 4.43 ± 0.13 sec) compared to C (4.56 ± 0.18 vs. 4.50 ± 0.16 sec). Jump and squat performance increased pre to post with no differences between groups. Our findings indicate that an off season SNEI is effective at improving sport nutrition knowledge and some, but not all, nutrient intakes and performance measures in Division I baseball players.

  10. Effect of vegetable diets versus diets with processed animal proteins on performance and health status of laying hens = Effecten van plantaardig voer versus voer met dierlijke eiwitten op productieprestaties en gezondheidsstatus van leghennen

    NARCIS (Netherlands)

    Veldkamp, T.; Krimpen, van M.M.; Jansman, A.J.M.

    2008-01-01

    Meat and bone meal and meat meal in diets and their effects on performance and health status of laying hens has been reviewed. Properties of dietary animal proteins are compared with dietary vegetable proteins and possible causative factors for differences in performance and health are described in

  11. Interdependence of plant water status with photosynthetic performance and root defense responses in Vigna radiata (L.) Wilczek under progressive drought stress and recovery.

    Science.gov (United States)

    Sengupta, Debashree; Guha, Anirban; Reddy, Attipalli Ramachandra

    2013-10-05

    correlations with leaf water content, stomatal conductance as well as transpirational water loss dynamics and a significant negative correlation with the corresponding drought-induced expression patterns of ascorbate, guaiacol peroxidase and proline in roots of V. radiata. The study provides new insights into the plant water status-dependent interrelationship between photosynthetic performance and major root defense responses of V. radiata under progressive drought conditions. Copyright © 2013 Elsevier B.V. All rights reserved.

  12. The effects of regular consumption of a multiple micronutrient fortified milk beverage on the micronutrient status of school children and on their mental and physical performance.

    Science.gov (United States)

    Kuriyan, Rebecca; Thankachan, Prashanth; Selvam, Sumithra; Pauline, Maria; Srinivasan, K; Kamath-Jha, Shilpa; Vinoy, Sophie; Misra, Situn; Finnegan, Yvonne; Kurpad, Anura V

    2016-02-01

    Multiple micronutrient deficiencies exist in school going children in India and bridging the gap between nutrient intake and requirements is an effective way to combat the deficiencies. This study aimed to test the effect of a multi-micronutrient fortified malt and cocoa based milk beverage on the micronutrient status, cognition, physical performance and nutritional deficiencies of 7-10 years old south Indian children. A randomized, double blind placebo controlled study design was used with normal healthy children from low to middle income families, aged 7-10 years randomly assigned to receive either a multi-micronutrient fortified or an unfortified milk based control drink. The drinks were provided 6 days/week for 5 months. Assessments included anthropometry, blood biochemistry, physical performance and cognition at baseline and endline. The baseline characteristics of the study groups were similar. The changes in body weight and height were similar between the groups at the end of the study. Levels of vitamin B12, red cell folate and vitamin B2 significantly improved in the intervention group, while vitamin D, selenium and body iron showed no difference. The Hemoglobin (Hb) and serum ferritin levels of the control group decreased at endline, while those in the intervention group maintained their levels. The serum transferrin receptor levels increased in both the groups. The prevalence of iron deficiency and Vitamin B2 deficiency were significantly lower in the intervention group at endline. Overall improvement in cognitive and physical performance was seen in both the groups at endline, with no significant differences between the groups. The micronutrient fortified milk based drink was efficacious in improving the micronutrient status of Vitamin B2, Vitamin B12 and red cell folate and in preventing a decline in Hb level compared to an unfortified milk based drink. It also reduced anemia and the risk of deficiencies of iron, and B12, in apparently healthy children

  13. Effects of High Performance Inulin Supplementation on Glycemic Status and Lipid Profile in Women with Type 2 Diabetes: A Randomized, Placebo-Controlled Clinical Trial

    Directory of Open Access Journals (Sweden)

    Parvin Dehghan

    2013-06-01

    Full Text Available Background: Type 2 diabetes mellitus, as a noncommunicable disease, is the main public health challenge in the 21st century. The prevalence of di¬abetes mellitus adjusted for the world population in Iran was 8% until the year 2010. Lipid levels are considered as important parameters to be eva¬luated, as high serum lipid levels are often reported as a complication in patients with diabetes mellitus. It is claimed that functional foods may im¬prove complications of diabetes mellitus, so this study was designed to evaluate the effects of high performance inulin on glycemic status and lipid profile of women with type 2 diabetes.Methods: The study was a randomized controlled clinical trial. Forty-nine type 2 diabetic females (fiber intake <30g/d, 25status and lipid profile indices were measured pre and post intervention. Data were analyzed using SPSS software (verision11.5. Paired, unpaired t-test and ANCOVA were used to compare quantitative variables.Results: Supplementation with inulin caused a significant reduction in FBS (8.50%, HbA1c (10.40%, total cholesterol (12.90%, triglyceride (23.60 %, LDL-c (35.30 %, LDL-c/HDL-c ratio (16.25% and TC/HDL-c ratio (25.20% and increased HDL-c (19.90%. The changes for the control group parameters were not significant at the end of study. Conclusion: Inulin may help to control diabetes and its complications via improving glycemic and lipid parameters.

  14. Effects of rice bran on performance, egg quality, oxidative status, yolk fatty acid composition, and fatty acid metabolism-related gene expression in laying ducks.

    Science.gov (United States)

    Ruan, D; Lin, Y C; Chen, W; Wang, S; Xia, W G; Fouad, A M; Zheng, C T

    2015-12-01

    The study was designed to evaluate the effects of different dietary levels of rice bran (RB) in laying duck diets on performance, egg quality, oxidation status, egg yolk fatty acid composition, and hepatic expression of fatty acid metabolism-related genes. Longyan females (1080) with similar BW at 19 wk of age were randomly assigned to 6 dietary treatments, each consisting of 6 replicates of 30 birds. The basal diet (I) was a typical corn-soybean ration while the experimental diets (II to VI) substituted RB for corn and wheat bran and a small reduction of soybean meal. The level of substitution in diets (II to VI) was 6%, 12%, 18%, 24%, and 30%, respectively. The experiment lasted for 12 wks. Average egg weight and daily egg mass decreased linearly as the level of RB inclusion increased (Pegg yolk linearly decreased with increasing RB, and many of the key polyunsaturated fatty acids (PUFA), like C18:2 n-6 and C18:3 n-3, linearly increased (Pegg yolk cholesterol or triglyceride content (P>0.05). In conclusion, the current study suggests that ducks from 19 to 31 wk could be fed diets with up to about 18% RB without effect on the number of eggs produced, egg quality, and oxidative status. Increasing amounts of RB linearly increased egg yolk concentrations of key fatty acids like C18:2 n-6 and C18:3 n-3 and decreased the hepatic abundance of FAS and SREBP-1 transcripts. © 2015 Poultry Science Association Inc.

  15. Effects of in ovo feeding of creatine pyruvate on the hatchability, growth performance and energy status in embryos and broiler chickens.

    Science.gov (United States)

    Zhao, M M; Gao, T; Zhang, L; Li, J L; Lv, P A; Yu, L L; Gao, F; Zhou, G H

    2017-10-01

    The effects of in ovo feeding (IOF) of creatine pyruvate (CrPyr) on the hatchability, growth performance and energy status of embryos and broilers (Arbor Acres) were investigated. Five treatments were arranged as non-injected treatment (Control), 0.6 ml physiological saline (0.75%) injected treatment (Saline), and IOF treatments injected with 0.6 ml physiological saline (0.75%) containing 3, 6 or 12 mg CrPyr (CrPyr3, CrPyr6 or CrPyr12) into the amnion per fertile egg on day 17.5 of incubation. After hatching, 80 male chicks from each treatment with similar weight close to the average BW of their pooled group were selected and randomly assigned into eight replicates of 10 chicks each. The results showed that the hatchability was not affected among groups, whereas the hatching weight of broilers in CrPyr12 was significantly higher than the control and saline groups (P0.05). Irrespective of dosage, the concentrations of creatine and phosphocreatine, and activities of creatine kinase in embryos were enhanced in CrPyr treatments at 19 E when compared with the control and saline groups (P<0.05). The activities of glucose-6-phosphatase in liver in CrPyr6 and CrPyr12 treatments were higher than the control and saline groups at 19 E (P<0.05). In conclusion, these results indicated that IOF of CrPyr, especially at the level of 12 mg/egg, could improve energy status of embryos and hatchlings, which was useful for enhancing hatching weight, BW and pectoral muscle weight until the end of the experiments at 21 days post-hatch in broilers.

  16. Short-course radiotherapy, with elective delay prior to surgery, in patients with unresectable rectal cancer who have poor performance status or significant co-morbidity

    International Nuclear Information System (INIS)

    Hatfield, Paul; Hingorani, Mohan; Radhakrishna, Ganesh; Cooper, Rachel; Melcher, Alan; Crellin, Adrian; Kwok-Williams, Michelle; Sebag-Montefiore, David

    2009-01-01

    Background and purpose: Standard treatment for rectal cancer which threatens the expected plane of resection on MRI imaging is long-course, pre-operative chemoradiotherapy (1.8-2 Gy, 25-28 fractions). Not all patients are suitable for this because of age, poor performance status or co-morbidities. We describe our experience of short-course (5 x 5 Gy) pre-operative radiotherapy with planned, delayed surgery (SCPRT-delay) in this patient group. Materials and methods: Between April 2001 and October 2007, 43 patients were selected for SCPRT-delay. The clinical records were retrospectively evaluated. Results: Median age was 82 (range 58-87). Forty-one patients had radiotherapy of which 26 (61%) were subsequently able to have surgery. Of these, R0, R1 and R2 resections were performed in 22, 2 and 2 patients, respectively. Treatment was well tolerated, although two patients required hospital admission for management of diarrhoea and one developed significant late small bowel toxicity, attributable to radiotherapy. In those undergoing R0 or R1 resection there have been no local recurrences (median follow-up 18 months). Median survival for the whole group was 23 months, although this was 44 months in those undergoing surgery. Conclusions: SCPRT-delay appears to be a useful alternative to long-course pre-operative chemoradiotherapy in this high-risk group of patients.

  17. Effects of a long-acting trace mineral rumen bolus supplement on growth performance, metabolic profiles, and trace mineral status of growing camels.

    Science.gov (United States)

    Alhidary, Ibrahim A; Abdelrahman, Mutassim M; Harron, Raafat M

    2016-04-01

    A study was conducted to evaluate the effects of a long-acting trace mineral rumen bolus (TMB) supplement on the productive performance, metabolic profiles, and trace mineral status of growing camels under natural grazing conditions. Fifteen 6-month-old growing male camels (average bodyweight 139.51 ± 26.49 kg) were used in a 150-day trial. Animals were individually housed in a shaded pen and randomly assigned to receive zero (control group, CON), one (TMB1), or two (TMB2) long-acting TMBs. Feed intake was measured weekly, and camels were weighed monthly. Blood samples were collected from all camels on days 1, 30, 60, 90, 120, and 150 to obtain metabolic profiles. Zinc, selenium, copper, cobalt, and manganese concentrations were determined in the diet, serum, and liver. In comparison with controls, giving camels one TMB increased the average daily gain (14.38%; P camels in the TMB2 group. These data indicate that TMB supplementation has positive effects on the growth performance and trace mineral profiles of camels. Different levels, sources, and synergistic combinations of trace minerals can be used in further studies to elucidate their abilities to increase productive variables as well as their availability and cost to the camel industry.

  18. Effect of Dietary Cation-Anion Difference during Prepartum and Postpartum Periods on Performance, Blood and Urine Minerals Status of Holstein Dairy Cow

    Directory of Open Access Journals (Sweden)

    A. Razzaghi

    2012-04-01

    Full Text Available Twenty four periparturient cows were used to determine the effects of DCAD on acid-base balance, plasma and urine mineral concentrations, health status, and subsequent lactation performance. Each group of 12 cows received either a diet containing −100 DCAD or +100 DCAD for 21 d prepartum. Both anionic and cationic groups were divided into two groups, one received a +200 DCAD and the other +400 DCAD diet for 60 d postpartum. Prepartum reduction of DCAD decreased DMI, urinary and blood pH, urinary concentrations of Na or K and increased plasma and urinary Ca, Mg, Cl and S. Also cows fed −100 DCAD diet consumed the most dry matter in the first 60 d after calving. Postpartum +400 DCAD increased milk fat and total solid percentages, urinary and blood pH and urinary Na and K concentrations, but urinary Ca, P, Cl and S contents decreased. Greater DMI, FCM yields were observed in cows fed a diet of +400 DCAD than +200 DCAD. No case of milk fever occurred for any diets but feeding with a negative DCAD diet reduced placenta expulsion time. In conclusion, feeding negative DCAD in late gestation period and high DCAD in early lactation improves performance and productivity of dairy cows.

  19. Socioeconomic status, child enrichment factors, and cognitive performance among preschool-age children: results from the Follow-Up of Growth and Development Experiences study.

    Science.gov (United States)

    Christensen, Deborah L; Schieve, Laura A; Devine, Owen; Drews-Botsch, Carolyn

    2014-07-01

    Lower cognitive performance is associated with poorer health and functioning throughout the lifespan and disproportionately affects children from lower socioeconomic status (SES) populations. Previous studies reporting positive associations between child home enrichment and cognitive performance generally had a limited distribution of SES. We evaluated the associations of SES and child enrichment with cognitive performance in a population with a wide range of SES, particularly whether enrichment attenuates associations with SES. Children were sampled from a case-control study of small-for-gestational-age (SGA) conducted in a public hospital serving a low SES population (final n=198) and a private hospital serving a middle-to-high SES population (final n=253). SES (maternal education and income) and perinatal factors (SGA, maternal smoking and drinking) were obtained from maternal birth interview. Five child home enrichment factors (e.g. books in home) and preschool attendance were obtained from follow-up interview at age 4.5 years. Cognitive performance was assessed with the Differential Ability Scales (DAS), a standardized psychometric test administered at follow-up. SES and enrichment scores were created by combining individual factors. Analyses were adjusted for perinatal factors. Children from the public birth hospital had a significantly lower mean DAS general cognitive ability (GCA) score than children born at the private birth hospital (adjusted mean difference -21.4, 95% CI: -24.0, -18.7); this was substantially attenuated by adjustment for individual SES, child enrichment factors, and preschool attendance (adjusted mean difference -5.1, 95% CI: -9.5, -0.7). Individual-level SES score was associated with DAS score, beyond the general SES effect associated with hospital of birth. Adjustment for preschool attendance and home enrichment score attenuated the association between individual SES score and adjusted mean DAS-GCA among children born at both of the

  20. Effect of dietary poly-β-hydroxybutyrate (PHB) on growth performance, intestinal health status and body composition of Pacific white shrimp Litopenaeus vannamei (Boone, 1931).

    Science.gov (United States)

    Duan, Yafei; Zhang, Yue; Dong, Hongbiao; Zheng, Xiaoting; Wang, Yun; Li, Hua; Liu, Qingsong; Zhang, Jiasong

    2017-01-01

    In the present study, the effect of dietary supplementation of poly-β-hydroxybutyrate (PHB) on the growth performance, intestinal digestive and immune function, intestinal short-chain fatty acids (SCFA) content and body composition of Pacific white shrimp Litopenaeus vannamei (Boone, 1931) was evaluated. The shrimp was fed for 35 days with four different diets: 0%, 1%, 3% and 5% PHB supplemented feed. The results indicated that supplementation of PHB significantly increased the growth performance of the shrimp, and the feed conversion rate (FCR) in 3%PHB treatment group was significantly lower than the control (P PHB treatment groups were all significantly higher than that of the control (P PHB treatment (P > 0.05). The activities of intestinal immune enzymes such as total antioxidant capacity (T-AOC) and inducible nitric oxide synthase (iNOS) was significantly induced by 3%PHB treatment (P PHB treatment and nitric oxide (NO) content was significantly induced in three PHB treatments. Meanwhile, PHB induced significantly the expression level of intestinal heat shock protein 70 (HSP70), Toll and immune deficiency (Imd) gene. HE staining showed that PHB induced the intestinal health status of L. vannamei. Intestinal SCFA content analysis revealed that the content of propionic and butyric acid of 3%PHB treatment were significantly higher than that of the control (P PHB treatments, and the crude lipid in 1% and 5%PHB treatments were all significantly higher than the control (P PHB could improve the growth performance, modulated intestinal digestive and immune function, increased intestinal SCFA content and body composition in L. vannamei, and the optimum dietary PHB requirement by L. vannamei was estimated at 3% (w/w) diet. Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. Dietary supplementation of biofloc influences growth performance, physiological stress, antioxidant status and immune response of juvenile sea cucumber Apostichopus japonicus (Selenka).

    Science.gov (United States)

    Chen, Jinghua; Ren, Yichao; Wang, Guodong; Xia, Bin; Li, Yuquan

    2018-01-01

    Bioflocs are rich in various probiotics and bioactive compounds, which play an important role in improving growth and health status of aquatic organisms. A 60-day experiment was conducted to investigate the effects of dietary supplementation of biofloc on growth performance, digestive enzyme activity, physiological stress, antioxidant status, expression of immune-related genes and disease resistance of sea cucumber Apostichopus japonicus. Juvenile sea cucumbers were fed five experimental diets containing graded levels of biofloc from 0% to 20% (referred as B0, B5, B10, B15 and B20, respectively). The results showed that the sea cucumbers at dietary supplementation levels of 10%-15% biofloc had significantly higher specific growth rate (SGR) compared to control group (diet B0). Digestive enzyme activity increased with the increasing of dietary biofloc level, while no significant difference was found between diets B15 and B20. Dietary supplementation of biofloc also had significant influences on physiological stress parameters except for lactate. There was no significant discrepancy in total coelomocytes counts (TCC) in coelomic fluid of sea cucumber between the treatments. Phagocytosis and respiratory burst of cellular immune at 15% and 20% biofloc levels were significantly higher than those of control group. Significant increases in superoxide dismutase (SOD), total nitric oxide synthase (T-NOS), lysozyme (LSZ), acid phosphatase (ACP) and alkaline phosphatase (AKP) activities of sea cucumber were found at highest dietary supplementation level of 20% biofloc. The expression patterns of immune-related genes (i.e., Hsp90, Hsp70, p105, Rel, NOS and LSZ) in tissues of sea cucumber were analyzed between the experimental diets, and a general trend of up-regulation was observed at higher biofloc levels. Furthermore, dietary 10%-20% biofloc significantly reduced cumulative mortality of sea cucumber after being challenged with Vibrio splendidus. In conclusion, dietary

  2. Effect of change in symptoms, respiratory status, nutritional profile and quality of life on response to treatment for advanced non-small cell lung cancer.

    Science.gov (United States)

    Mohan, Anant; Singh, P; Kumar, S; Mohan, C; Pathak, A K; Pandey, R M; Guleria, R

    2008-01-01

    Quality of life (QOL), and pulmonary and nutritional parameters are important outcome measures during treatment of lung cancer; however, the effect of chemotherapy on these factors and their relationship with clinical response is unclear. Patients with non-small cell lung cancer (NSCLC) were evaluated for symptom profile, nutritional status (using anthropometry), pulmonary functions by spirometry and six minute walk distance (6 MWD), and QOL using the WHO-QOL Bref 26 questionnaire, before and after chemotherapy. Forty-four patients were studied (mean (SD) age, 55 (10) years, 75% males). The majority (98%) had stage III or IV disease and 72% were current / ex-smokers with median pack-years of 27.0 (range, 0.5-90). Some 61% had a Karnofsky Performance Scale (KPS) 70 or 80. The commonest symptoms were coughing, dyspnea, chest pain, anorexia and fever (79%, 72%, 68%, 57% and 40%, respectively). The mean (SD) 6 MWD was 322.5 (132.6) meters. The mean (SD) percentage forced vital capacity (FVC %), and forced expiratory volume in one second (FEV1 %) were 64.7 (18.8) and 57.8 (19.4), respectively. The mean (SD) QOL scores for the physical, psychological, social, and environmental domains were 52.9 (20.5), 56.1 (17.9), 64.5 (21.8), 57.1 (16.6), respectively. Fourteen patients (32%) responded to chemotherapy. Non-responders had significantly higher baseline occurrence of fever, anorexia, and weight loss, higher pack-years of smoking and poorer KPS compared to responders. Overall, chemotherapy caused significant decline in the frequency of coughing, dyspnea, chest pain, fever, anorexia, weight loss, and improvement in hemoglobin and albumin levels. There was no significant improvement in pulmonary functions, nutritional status, or QOL scores after treatment. Lung cancer patients have a poor QOL. Although chemotherapy provides significant symptomatic benefit, this does not translate into similar benefit in respiratory and nutritional status or QOL. Patients with constitutional

  3. Loose-parts monitoring: present status of the technology, its implementation in U.S. reactors, and some recommendations for achieving improved performance

    International Nuclear Information System (INIS)

    Kryter, R.C.; Ricker, C.W.; Jones, J.E.

    1977-01-01

    An assessment of the technical development status of loose-parts monitoring systems (LPMS) and their performance record to data in commercial light-water-cooled nuclear reactor plants was made during the spring of 1977, using an on-site personal interview and equipment demonstration approach. The study revealed that while presently demonstrated LPMS technology does indeed provide a capability for detecting the presence of those relatively massive loose parts that would likely constitute a serious operational or safety hazard to the plant, it unfortunately affords little information useful to the determination of the parts' safety significance and has not yet attained the levels of sophistication and reliability ordinarily associated with safety systems. A definite need was found for specification of the functional requirements for LPMS, in the form of a clear and comprehensive statement of NRC policy regarding the formulation and implementation of safety-oriented, yet operationally practicable, loose-parts monitoring programs for both existing and future nuclear generating stations so that overall objectives of both the utilities and the regulatory agency might be satisfied simultaneously

  4. Cetuximab plus FOLFOX for Patients with Metastatic Colorectal Cancer with Poor Performance Status and/or Severe Tumor-Related Complications

    Science.gov (United States)

    Shitara, Kohei; Yokota, Tomoya; Takahari, Daisuke; Shibata, Takashi; Sato, Yozo; Tajika, Masahiro; Ura, Takashi; Muro, Kei

    2010-01-01

    Introduction Cetuximab-based chemotherapy showed a statistically significantly higher response rate compared with chemotherapy such as FOLFOX. Therefore, FOLFOX plus cetuximab is suspected to be the best regimen to alleviate tumor-related symptoms with a high response rate. Case Report Here we present the results of 8 consecutive patients with metastatic colorectal cancer with poor performance status and/or severe complications who were treated with first-line FOLFOX with cetuximab. Six of 8 patients achieved an apparent clinical benefit, including radiological response and symptoms improvement. Two patients with BRAF mutation could achieve neither clinical benefit nor radiological response. Conclusion Although an optimal line of therapy with cetuximab is unclear yet with bevacizumab in mind, we propose that patients who need a tumor response to alleviate their symptoms due to advanced disease might be candidates for first-line cetuximab-based therapy as shown in our cases. Additionally, patients with BRAF mutant tumors might be important candidates for novel targeted therapy in the future to improve their poor prognosis. PMID:21347194

  5. Cetuximab plus FOLFOX for Patients with Metastatic Colorectal Cancer with Poor Performance Status and/or Severe Tumor-Related Complications

    Directory of Open Access Journals (Sweden)

    Kohei Shitara

    2010-07-01

    Full Text Available Introduction: Cetuximab-based chemotherapy showed a statistically significantly higher response rate compared with chemotherapy such as FOLFOX. Therefore, FOLFOX plus cetuximab is suspected to be the best regimen to alleviate tumor-related symptoms with a high response rate. Case Report: Here we present the results of 8 consecutive patients with metastatic colorectal cancer with poor performance status and/or severe complications who were treated with first-line FOLFOX with cetuximab. Six of 8 patients achieved an apparent clinical benefit, including radiological response and symptoms improvement. Two patients with BRAF mutation could achieve neither clinical benefit nor radiological response. Conclusion: Although an optimal line of therapy with cetuximab is unclear yet with bevacizumab in mind, we propose that patients who need a tumor response to alleviate their symptoms due to advanced disease might be candidates for first-line cetuximab-based therapy as shown in our cases. Additionally, patients with BRAF mutant tumors might be important candidates for novel targeted therapy in the future to improve their poor prognosis.

  6. Associations between socioeconomic status and primary total knee joint replacements performed for osteoarthritis across Australia 2003-10: data from the Australian Orthopaedic Association National Joint Replacement Registry.

    Science.gov (United States)

    Brennan, Sharon L; Lane, Stephen E; Lorimer, Michelle; Buchbinder, Rachelle; Wluka, Anita E; Page, Richard S; Osborne, Richard H; Pasco, Julie A; Sanders, Kerrie M; Cashman, Kara; Ebeling, Peter R; Graves, Stephen E

    2014-10-28

    Relatively little is known about the social distribution of total knee joint replacement (TKR) uptake in Australia. We examine associations between socioeconomic status (SES) and TKR performed for diagnosed osteoarthritis 2003-10 for all Australian males and females aged ≥ 30 yr. Data of primary TKR (n=213,018, 57.4% female) were ascertained from a comprehensive national joint replacement registry. Residential addresses were matched to Australian Census data to identify area-level social disadvantage, and categorised into deciles. Estimated TKR rates were calculated. Poisson regression was used to model the relative risk (RR) of age-adjusted TKR per 1,000py, stratified by sex and SES. A negative relationship was observed between TKR rates and SES deciles. Females had a greater rate of TKR than males. Surgery utilisation was greatest for all adults aged 70-79 yr. In that age group differences in estimated TKR per 1,000py between deciles were greater for 2010 than 2003 (females: 2010 RR 4.32 and 2003 RR 3.67; males: 2010 RR 2.04 and 2003 RR 1.78). Identifying factors associated with TKR utilisation and SES may enhance resource planning and promote surgery utilisation for end-stage osteoarthritis.

  7. Self-reported balance status is not a reliable indicator of balance performance in adolescents at one-month post-concussion.

    Science.gov (United States)

    Rochefort, Coralie; Walters-Stewart, Coren; Aglipay, Mary; Barrowman, Nick; Zemek, Roger; Sveistrup, Heidi

    2017-11-01

    To determine if self-reported balance symptoms can be used as a proxy for measures of the center of pressure (COP) to identify balance deficits in a group of concussed adolescents. Case-control. Thirteen adolescents 1-month post-concussion who reported ongoing balance problems (Balance+), 20 adolescent 1-month post-concussion who reported no balance problems (Balance-), and 30 non-injured adolescents (control) completed a series of balance tests. Participants completed two 2-min trials standing on a Nintendo Wii Balance Board™ during which the COP under their feet was recorded: i) double-leg stance, eyes open; ii) double-leg stance, eyes closed. Participants also completed a dual-task condition combining a double-leg stance and a Stroop Colour-word test. Participants in both the Balance+ and Balance- group swayed over a larger ellipse area compared to the control group while completing the Eyes Closed (Balance+, p=0.002; Balance-, p=0.002) and Dual-Task (Balance+, p=0.001; Balance-, p=0.004) conditions and performed the Dual-Task condition with faster medio-lateral velocity (Balance+, p=0.003; Balance-, p=0.009). The participants in the Balance- group also swayed over a larger ellipse area compared to the control group while completing the Eyes Open condition (p=0.005). No significant differences were identified between the Balance+ and Balance- groups. At 1-month post-concussion, adolescents demonstrated balance deficits compared to non-injured adolescents regardless of whether they reported balance problems. These results suggest that self-reported balance status might not be an accurate reflection of balance performance following a concussion in adolescents. Copyright © 2017 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  8. Spectral analysis-based risk score enables early prediction of mortality and cerebral performance in patients undergoing therapeutic hypothermia for ventricular fibrillation and comatose status

    Science.gov (United States)

    Filgueiras-Rama, David; Calvo, Conrado J.; Salvador-Montañés, Óscar; Cádenas, Rosalía; Ruiz-Cantador, Jose; Armada, Eduardo; Rey, Juan Ramón; Merino, J.L.; Peinado, Rafael; Pérez-Castellano, Nicasio; Pérez-Villacastín, Julián; Quintanilla, Jorge G.; Jiménez, Santiago; Castells, Francisco; Chorro, Francisco J.; López-Sendón, J.L.; Berenfeld, Omer; Jalife, José; López de Sá, Esteban; Millet, José

    2017-01-01

    Background Early prognosis in comatose survivors after cardiac arrest due to ventricular fibrillation (VF) is unreliable, especially in patients undergoing mild hypothermia. We aimed at developing a reliable risk-score to enable early prediction of cerebral performance and survival. Methods Sixty-one out of 239 consecutive patients undergoing mild hypothermia after cardiac arrest, with eventual return of spontaneous circulation (ROSC), and comatose status on admission fulfilled the inclusion criteria. Background clinical variables, VF time and frequency domain fundamental variables were considered. The primary and secondary outcomes were a favorable neurological performance (FNP) during hospitalization and survival to hospital discharge, respectively. The predictive model was developed in a retrospective cohort (n=32; September 2006–September 2011, 48.5 ± 10.5 months of follow-up) and further validated in a prospective cohort (n = 29; October 2011–July 2013, 5 ± 1.8 months of follow-up). Results FNP was present in 16 (50.0%) and 21 patients (72.4%) in the retrospective and prospective cohorts, respectively. Seventeen (53.1%) and 21 patients (72.4%), respectively, survived to hospital discharge. Both outcomes were significantly associated (p < 0.001). Retrospective multivariate analysis provided a prediction model (sensitivity= 0.94, specificity = 1) that included spectral dominant frequency, derived power density and peak ratios between high and low frequency bands, and the number of shocks delivered before ROSC. Validation on the prospective cohort showed sensitivity = 0.88 and specificity = 0.91. A model-derived risk-score properly predicted 93% of FNP. Testing the model on follow-up showed a c-statistic ≥ 0.89. Conclusions A spectral analysis-based model reliably correlates time-dependent VF spectral changes with acute cerebral injury in comatose survivors undergoing mild hypothermia after cardiac arrest. PMID:25828128

  9. A Comparative Performance Analysis of Multispectral and RGB Imaging on HER2 Status Evaluation for the Prediction of Breast Cancer Prognosis.

    Science.gov (United States)

    Liu, Wenlou; Wang, Linwei; Liu, Jiuyang; Yuan, Jingping; Chen, Jiamei; Wu, Han; Xiang, Qingming; Yang, Guifang; Li, Yan

    2016-12-01

    Despite the extensive application of multispectral imaging (MSI) in biomedical multidisciplinary researches, there is a paucity of data available regarding the implication of MSI in tumor prognosis prediction. We compared the behaviors of multispectral (MS) and conventional red-green-blue (RGB) images on assessment of human epidermal growth factor receptor 2 (HER2) immunohistochemistry to explore their impact on outcome in patients with invasive breast cancer (BC). Tissue microarrays containing 240 BC patients were introduced to compare the performance of MS and RGB imaging methods on the quantitative assessment of HER2 status and the prognostic value of 5-year disease-free survival (5-DFS). Both the total and average signal optical density values of HER2 MS and RGB images were analyzed, and all patients were divided into two groups based on the different 5-DFS. The quantification of HER2 MS images was negatively correlated with 5-DFS in lymph node-negative and -positive patients (Panalysis indicated that the hazard ratio (HR) of HER2 MS was higher than that of HER2 RGB (HR=2.454; 95% confidence interval [CI], 1.636-3.681 vs HR=2.060; 95% CI, 1.361-3.119). Additionally, area under curve (AUC) by receiver operating characteristic analysis for HER2 MS was greater than that for HER2 RGB (AUC=0.649; 95% CI, 0.577-0.722 vs AUC=0.596; 95% CI, 0.522-0.670) in predicting the risk for recurrence. More importantly, the quantification of HER2 MS images has higher prediction accuracy than that of HER2 RGB images (69.6% vs 65.0%) on 5-DFS. Our study suggested that better information on BC prognosis could be obtained from the quantification of HER2 MS images and MS images might perform better in predicting BC prognosis than conventional RGB images. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  10. Effect of dietary seaweed extracts and fish oil supplementation in sows on performance, intestinal microflora, intestinal morphology, volatile fatty acid concentrations and immune status of weaned pigs.

    Science.gov (United States)

    Leonard, S G; Sweeney, T; Bahar, B; Lynch, B P; O'Doherty, J V

    2011-02-01

    A 2x2 factorial experiment (ten sows per treatment) was conducted to investigate the effect of maternal dietary supplementation with a seaweed extract (SWE; 0 v. 10·0 g/d) and fish oil (FO; 0 v. 100 g/d) inclusion from day 109 of gestation until weaning (day 26) on pig performance post-weaning (PW) and intestinal morphology, selected microflora and immune status of pigs 9 d PW. The SWE contained laminarin (10 %), fucoidan (8 %) and ash (82 %) and the FO contained 40 % EPA and 25 % DHA. Pigs weaned from SWE-supplemented sows had higher daily gain (P=0·063) between days 0 and 21 PW and pigs weaned from FO-supplemented sows had higher daily gain (P<0·05) and gain to feed ratio (P<0·01) between days 7 and 14 PW. There was an interaction between maternal SWE and FO supplementation on caecal Escherichia coli numbers (P<0·05) and the villous height to crypt depth ratio in the ileum (P<0·01) and jejunum (P<0·05) in pigs 9 d PW. Pigs weaned from SWE-supplemented sows had lower caecal E. coli and a higher villous height to crypt depth ratio in the ileum and jejunum compared with non-SWE-supplemented sows (P<0·05). There was no effect of SWE on E. coli numbers and villous height to crypt depth ratio with FO inclusion. Maternal FO supplementation induced an increase in colonic mRNA abundance of IL-1α and IL-6 (P<0·05), while SWE supplementation induced an increase in ileal TNF-α (P<0·01) and colonic TFF3 mRNA expression (P<0·05). In conclusion, these results demonstrate that SWE and FO supplementation to the maternal diet influenced the gastrointestinal environment and performance of the weaned pig.

  11. Triennial Growth Symposium--Effects of dietary 25-hydroxycholecalciferol and cholecalciferol on blood vitamin D and mineral status, bone turnover, milk composition, and reproductive performance of sows.

    Science.gov (United States)

    Weber, G M; Witschi, A-K M; Wenk, C; Martens, H

    2014-03-01

    To evaluate the role of vitamin D3 during gestation and lactation of sows, 2 independent experiments were performed with the aim of investigating sow reproductive performance, milk composition (study 1 only), and changes in blood status of 25-hydroxycholecalciferol (25-OH-D3), 1,25-dihydroxycholecalciferol (1,25-(OH)2-D3; study 2 only), minerals, and bone markers of sows during gestation and lactation. Study 1 comprised 39 primi- and multiparous crossbred sows fed 1 of 3 barley meal-based diets fortified with 200 IU/kg vitamin D3 (NRC, 1998; treatment DL), 2,000 IU/kg vitamin D3 (cholecalciferol; treatment DN), or 50 μg 25-OH-D3 (calcidiol; treatment HD)/kg feed. This study was conducted over a 4-parity period under controlled conditions. Study 2, running over 1 parity only, was performed in a commercial farm with 227 primi- and multiparous sows allocated to 2 dietary treatments: control (CON), receiving 2,000 IU vitamin D3/kg (equivalent to 50 μg/kg) feed (114 sows), and test (HYD), supplemented with 50 μg 25-OH-D3/kg feed (113 sows). Blood samples of sows were collected at 84 and 110d postcoitum and 1, 5, and 33 d postpartum (study 1) and at insemination and 28 and 80 d postinsemination as well as d 5 and 28 postpartum (study 2). Colostrum and milk samples in study 1 were obtained at 1, 9, and 33 d of lactation after oxytocin administration. Plasma 25-OH-D3 concentrations were increased (P < 0.05) in sows receiving 25-OH-D3 (HD and HYD) at any time of sampling whereas circulating plasma concentrations of 1,25-(OH)2-D3, Ca, and P were not affected by treatment. Milk concentrations of Ca and P were similar, but 25-OH-D3 content (except in colostrum) was clearly increased (P< 0.05) when 25-OH-D3 was fed. Most characteristics of sow reproductive performance responded similarly to the 2 sources and levels of vitamin D3, but weight gain of piglets between birth and weaning was decreased (P< 0.05) in offspring of DL and HD sows compared with animals of treatment DN

  12. Effects of Serum Albumin, Calcium Levels, Cancer Stage and Performance Status on Weight Loss in Parathyroid Hormone-Related Peptide Positive or Negative Patients with Cancer

    Directory of Open Access Journals (Sweden)

    Ji-Yeon Lee

    2018-03-01

    Full Text Available BackgroundA recent animal study showed that parathyroid hormone-related peptide (PTHrP is associated with cancer cachexia by promoting adipose tissue browning, and we previously demonstrated that PTHrP predicts weight loss (WL in patients with cancer. In this study, we investigated whether prediction of WL by PTHrP is influenced by clinical factors such as serum albumin, corrected calcium levels, cancer stage, and performance status (PS.MethodsA cohort of 219 patients with cancer whose PTHrP level was measured was enrolled and followed for body weight (BW changes. Subjects were divided into two groups by serum albumin (cutoff value, 3.7 g/dL, corrected calcium (cutoff value, 10.5 mg/dL, cancer stage (stage 1 to 3 or 4, or PS (Eastern Cooperative Oncology Group 0 to 1 or 2 to 4, respectively. Clinically significant WL was defined as either percent of BW change (% BW <−5% or % BW <−2% plus body mass index (BMI <20 kg/m2.ResultsAfter a median follow-up of 327 days, 74 patients (33.8% experienced clinically significant WL. A positive PTHrP level was associated with a 2-fold increased risk of WL after adjusting for age, baseline BMI, serum albumin, corrected calcium level, cancer stage, and PS. The effect of PTHrP on WL remained significant in patients with low serum albumin, stage 4 cancer, and good PS. Regardless of calcium level, the effect of PTHrP on WL was maintained, although there was an additive effect of higher calcium and PTHrP levels.ConclusionEarly recognition of patients with advanced cancer who are PTHrP positive with hypercalcemia or hypoalbuminemia is needed for their clinical management.

  13. Effects of dietary on antioxidant status, lipid profile, immune response and performance characteristics of broiler chickens reared under high ambient temperature

    Directory of Open Access Journals (Sweden)

    Sara Mirzaie

    2018-04-01

    Full Text Available Objective Spirulina has been recognized formerly as a filamentous spiral-shaped blue-green algae but more recently as a genus of photosynthetic bacteria (Arthrospira. This microorganism is considered as a rich source of essential nutrients for human and animals. The present study was conducted to determine potential application of Spirulina for heat-exposed broilers. Methods Two hundred and fifty Cobb 500 chicks with male to female in equal ratio with average initial weight of 615.6 g at 17 days of age were divided into 5 treatments with 5 replicates of 10 chicks. Treatment groups were as follows: positive and negative controls with 0% Spirulina supplement and three Spirulina receiving groups with 5 g/kg (0.5%, 10 g/kg (1%, and 20 g/kg (2% supplementation. Spirulina receiving groups as well as positive control were exposed to high ambient temperature at 36°C for 6 h/d from 38 to 44 days of age. Biochemical variables were measured in serum samples at 35, 38, 42, and 45 days of broiler chickens age. Results The results showed that supplementation of the diet with Spirulina decreased concentration of stress hormone and some serum lipid parameters while enhanced humoral immunity response and elevated antioxidant status whereas it didn’t meaningfully affect performance characteristics. Nevertheless, feed conversion ratio was improved numerically but not statistically in broilers fed with 1% Spirulina under high ambient temperature. Conclusion Overall, the present study suggests that alleviation of adverse impacts due to high ambient temperature at biochemical level including impaired enzymatic antioxidant system, elevated stress hormone and lipid profile can be approached in broiler chickens through supplementation of the diet with Spirulina platensis.

  14. The Effect of increasing levels of date palm (Phoenix dactylifera L.) seed on the performance, ruminal fermentation, antioxidant status and milk fatty acid profile of Saanen dairy goats.

    Science.gov (United States)

    Sharifi, M; Bashtani, M; Naserian, A A; Farhangfar, H

    2017-10-01

    This study was conducted to examine the effect of date palm (Phoenix dactylifera L.) seed (DPS) on the performance, ruminal fermentation, antioxidant status and milk fatty acid (FA) profile of dairy goats. Eight multiparous Saanen dairy goats, averaging 97 ± 7 days in milk (DIM) and 2150 ± 130 g of milk production, were used in a 4 × 4 replicated Latin square design. Experimental diets contained 0% (control), 6% (DPS6), 12% (DPS12) and 18% (DPS18) of DPS. Dry matter intake (DMI), milk production, and the composition and digestibility of the dry matter (DM), organic matter (OM), neutral detergent fibre (NDF) and crude protein (CP) were not affected by the diets. Adding DPS to the diet increased linearly total antioxidant capacity (TAC) in milk and blood (p content in milk and blood. Superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities in the blood, ruminal pH, NH 3 -N, ruminal total volatile fatty acid (VFA), acetate, butyrate, isovalerate and valeric acid concentration had no significant effect among the diets. The propionate acid concentration decreased linearly as DPS was added to the diet, and DPS18 had minimum propionate acid concentration (p < 0.05). The inclusion of DPS18 to diets increased linearly the proportion of C18:0 (compared to control) as well as cis-18:1, trans-18:1 (compared to control and DPS6) and decreased C14:1 (compared to control) in milk fat (p < 0.05). The concentration of conjugated linoleic acid (CLA) in DPS18 was higher than other diets (p = 0.04). The results of this study implied that replacing DPS with a part of dairy goats' ration had no negative effects on the performance of the animals and could also improve the antioxidant activity and increase the concentration of CLA in their milk. Journal of Animal Physiology and Animal Nutrition © 2017 Blackwell Verlag GmbH.

  15. Status epilepticus

    NARCIS (Netherlands)

    Hensiek, AE; Absalom, Anthony

    2006-01-01

    Status epilepticus is defined as epileptic activity that continues for more than 30 minutes as a single seizure or as recurrent seizures without inter-ictal return of consciousness. The seizure activity is usually classified as partial or generalized. Although status epilepticus is an uncommon

  16. Effects of shortening the close-up period length coupled with increased supply of metabolizable protein on performance and metabolic status of multiparous Holstein cows.

    Science.gov (United States)

    Farahani, T Amirabadi; Amanlou, H; Kazemi-Bonchenari, M

    2017-08-01

    This experiment was conducted to compare conventional (CON; 21 d) and shortened (SH; 10 d) close-up period, and evaluate the effect of shortened close-up period combined with feeding different metabolizable protein (MP) levels on dry matter (DM) intake, metabolic status, and performance of dairy cows. Forty-eight multiparous Holstein cows with similar parity, body weight (BW), and previous lactation milk yield were divided into 2 groups. The first group (n = 24) received the far-off diet from -60 to -21 d (CON), and the second group (n = 24) received same far-off diet from -60 to -10 d (SH) relative to expected parturition. Cows were then moved to individual stalls and randomly allocated to 1 of 3 close-up diets: low MP diet (LMP; MP = 79 g/kg of DM), medium MP diet (MMP; MP = 101 g/kg of DM), or high MP diet (HMP; MP = 118 g/kg of DM). Treatments were used in a 2 × 3 factorial arrangement with 2 lengths of close-up period (CON and SH) and 3 levels of MP (LMP, MMP, and HMP). All diets were fed for ad libitum intake during the close-up period. After calving, all cows received the same fresh cow diet. We found no interaction between close-up period length and MP levels for traits, except for postpartum serum fatty acids and β-hydroxybutyrate (BHB). The concentrations of postpartum serum fatty acids and BHB were higher on LMP than MMP and HMP diets in SH group. The cows of the SH group tended to produce less colostrum in the first milking than cows in CON group. The length of close-up period did not affect pre- and postpartum DM intake or energy balance of cows during the last week of prepartum, but cows of the CON group had greater BW changes during the last 3 wk before parturition than cows in SH group. Cows fed MMP and HMP diets consumed 1.2 and 1 kg more DM than for those fed LMP prepartum, respectively. The concentrations of prepartum BHB and Ca were higher for SH cows than CON group cows. Except for blood urea N concentration, no other blood metabolite in

  17. PERFORMANCE

    Directory of Open Access Journals (Sweden)

    M Cilli

    2014-10-01

    Full Text Available This study aimed to investigate the kinematic and kinetic changes when resistance is applied in horizontal and vertical directions, produced by using different percentages of body weight, caused by jumping movements during a dynamic warm-up. The group of subjects consisted of 35 voluntary male athletes (19 basketball and 16 volleyball players; age: 23.4 ± 1.4 years, training experience: 9.6 ± 2.7 years; height: 177.2 ± 5.7 cm, body weight: 69.9 ± 6.9 kg studying Physical Education, who had a jump training background and who were training for 2 hours, on 4 days in a week. A dynamic warm-up protocol containing seven specific resistance movements with specific resistance corresponding to different percentages of body weight (2%, 4%, 6%, 8%, 10% was applied randomly on non consecutive days. Effects of different warm-up protocols were assessed by pre-/post- exercise changes in jump height in the countermovement jump (CMJ and the squat jump (SJ measured using a force platform and changes in hip and knee joint angles at the end of the eccentric phase measured using a video camera. A significant increase in jump height was observed in the dynamic resistance warm-up conducted with different percentages of body weight (p 0.05. In jump movements before and after the warm-up, while no significant difference between the vertical ground reaction forces applied by athletes was observed (p>0.05, in some cases of resistance, a significant reduction was observed in hip and knee joint angles (p<0.05. The dynamic resistance warm-up method was found to cause changes in the kinematics of jumping movements, as well as an increase in jump height values. As a result, dynamic warm-up exercises could be applicable in cases of resistance corresponding to 6-10% of body weight applied in horizontal and vertical directions in order to increase the jump performance acutely.

  18. Use of probiotics intercropped with plant protein diets and their influence on the growth performance and immunological status of Senegalese sole (Solea senegalensis

    Directory of Open Access Journals (Sweden)

    Sónia Batista

    2014-06-01

    Full Text Available In Senegalese sole (Solea senegalensis aquaculture, infectious diseases represent a major challenge, leading to significant economic losses (Arijo et al, 2005. According to FAO / WHO (2001, probiotics are defined as "live micro-organisms which, when administered in adequate amounts, confer a health benefit on the host". Previous studies working with different fish species provided evidence on the effectiveness of various probiotic bacteria in promoting the fish welfare (Castex et al., 2009; Hernandez et al., 2010; Merrifield et al., 2011. In the current study, we evaluated the effects of dietary probiotic supplementation intercropped with plant protein as fishmeal replacement on the growth performance and immunological status in sole (Solea senegalensis. Fish were fed for 10 weeks on six isonitrogenous and isolipidic diets (55% protein and 8% lipid, dry matter basis, formulated to have 35% or 72% of fishmeal replacement by plant protein (PP35 or PP72 intercropped with three probiotic supplementation (NO – unsupplemented, PRO1 and PRO2, in a 2 × 3 factorial design. The probiotics were tested at a dosage recommended by the manufacturer. PRO1 was a multi-species probiotic bacteria (Bacillus sp., Pediococcus sp., Enterococcus sp., Lactobacillus sp. supplemented at 1.8 × 1010 CFU kg-1 diet (CFU - colony forming unit and PRO2 was an autolyzed yeast (Saccharomyces cerevisiae supplemented at 4g kg-1 diet. Zootechnical parameters were measured at start and the end of the feeding trial for growth performance determination. Plasma was collected at 3, 17, 38 and 73 days of feeding dietary treatment for the determination of innate immune response (plasma lysozyme and peroxidase contents, plasma alternative complement pathway activity – ACH50 in order to detect differences between treatments as well to identify the influence of long or short-time probiotic supplementation. Fish with an initial body weight of 33.1 ± 0.2 g grew to a maximum final body

  19. Interactive effect of high environmental ammonia and nutritional status on ecophysiological performance of European sea bass (Dicentrarchus labrax) acclimated to reduced seawater salinities.

    Science.gov (United States)

    Sinha, Amit Kumar; Rasoloniriana, Rindra; Dasan, Antony Franklin; Pipralia, Nitin; Blust, Ronny; De Boeck, Gudrun

    2015-03-01

    We investigated the interactive effect of ammonia toxicity, salinity challenge and nutritional status on the ecophysiological performance of European sea bass (Dicentrarchus labrax). Fish were progressively acclimated to normal seawater (32ppt), to brackish water (20ppt and 10ppt) and to hyposaline water (2.5ppt). Following acclimation to different salinities for two weeks, fish were exposed to high environmental ammonia (HEA, 20mg/L ∼1.18mM representing 50% of 96h LC50 value for ammonia) for 12h, 48h, 84h and 180h, and were either fed (2% body weight) or fasted (unfed for 7 days prior to HEA exposure). Biochemical responses such as ammonia (Jamm) and urea excretion rate, plasma ammonia, urea and lactate, plasma ions (Na(+), Cl(-) and K(+)) and osmolality, muscle water content (MWC) and liver and muscle energy budget (glycogen, lipid and protein), as well as branchial Na(+)/K(+)-ATPase (NKA) and H(+)-ATPase activity, and branchial mRNA expression of NKA and Na(+)/K(+)/2Cl(-) co-transporter (NKCC1) were investigated in order to understand metabolic and ion- osmoregulatory consequences of the experimental conditions. During HEA, Jamm was inhibited in fasted fish at 10ppt, while fed fish were still able to excrete efficiently. At 2.5ppt, both feeding groups subjected to HEA experienced severe reductions and eventually a reversion in Jamm. Overall, the build-up of plasma ammonia in HEA exposed fed fish was much lower than fasted ones. Unlike fasted fish, fed fish acclimated to lower salinities (10ppt-2.5ppt) could maintain plasma osmolality, [Na(+)], [Cl(-)] and MWC during HEA exposure. Thus fed fish were able to sustain ion-osmotic homeostasis which was associated with a more pronounced up-regulation in NKA expression and activity. At 2.5ppt both feeding groups activated H(+)-ATPase. The expression of NKCC1 was down-regulated at lower salinities in both fed and fasted fish, but was upregulated within each salinity after a few days of HEA exposure. Though an

  20. The effect of supplementation of clove and agrimony or clove and lemon balm on growth performance, antioxidant status and selected indices of lipid profile of broiler chickens.

    Science.gov (United States)

    Petrovic, V; Marcincak, S; Popelka, P; Simkova, J; Martonova, M; Buleca, J; Marcincakova, D; Tuckova, M; Molnar, L; Kovac, G

    2012-12-01

    The study investigated the effects of diet supplementation with 1% clove flower buds powder combined with either 0.2% lemon balm extract or 0.2% agrimony extract (each of the two pulverized extracts supplied through drinking water) on body weight of broilers, total feed intake, feed conversion ratio and the carcass yield, activity of superoxide dismutase (SOD, EC 1.15.1.1) and glutathione peroxidase (GSH-Px, EC 1.11.1.9) in blood, concentration of sulfhydryl (-SH) groups, malondialdehyde (MDA), vitamin A and E, low-density lipoproteins in the blood plasma, serum cholesterol, total lipids, triglycerides and high-density lipoproteins in broiler chickens at 42 days of age. On the day of hatching, 120 male and female broilers of Cobb 500 were randomly divided into three groups. The control group (1st group) of broilers received a basal diet (BD) without any feed and water additive. Both experimental groups of chicks were fed BD enriched with clove (Syzygium aromaticum L.) powder at a dose of 10 g/kg DM for 42 days. Moreover, either lemon balm (Mellisa officinalis L.) extract or agrimony (Agrimonia eupatoria L.) extract diluted with drinking water (2:1000) was given to broilers in the 2nd and 3rd group respectively. The results indicated that feeding the diets enriched with selected herbal supplements failed to affect the growth performance of broiler chickens at 42 days of age. In addition, this supplementation had no influence on the activities of SOD and GSH-Px, concentration of vitamin A and selected lipid metabolism indices. On the other hand, we observed beneficial effects on some indices of the antioxidant status (increased concentration of -SH groups and vitamin E, decreased concentration of MDA) in the blood of broilers in both experimental groups in comparison with the control group of chickens (p broilers supplied the combination of clove and lemon balm compared to clove and agrimony (vitamin E, 11.26 ± 0.73 vs. 9.73 ± 0.64 μmol/L, p

  1. Team-building through sailing: effects on health status, job satisfaction and work performance of health care professionals involved in organ and tissue donation.

    Science.gov (United States)

    Ponzin, Diego; Fasolo, Adriano; Vidale, Enrico; Pozzi, Annalaura; Bottignolo, Elisa; Calabrò, Francesco; Rupolo, Giampietro

    2015-01-01

    The aim of this study was to evaluate the effects of a team-building learning project on job satisfaction, psychological wellbeing, and performance of health care workers involved in the process of organ and tissue donation. The project was conducted between June and September 2011 and consisted of two one-day meetings and a one week sailing, involving 20 staff members. GHQ-12, MBI-HSS, and 25 items taken from the Multidimensional Organizational Health Questionnaire (MOHQ) were used to assess health status, burnout, and job satisfaction. Results of the descriptive analyses were expressed as mean ± SD and as counts and percentages; Chi-square test was used to evaluate statistical significance of differences before and after the initiative. 6 (30,0%) participants showed the likelihood to suffering from anxiety and depression (i.e. recognized as 'cases' by the GHQ-12), 3 (15.0%) of them at baseline and 3 (15.0%), different from the previous ones, in the post-intervention. The presence of stress was revealed in 9 (45.0%) and 12 subjects (60.0%) before and after the experience, respectively (6 subjects showed the presence of stress in both circumstances). We documented 4 burnout cases, 3 (15.0%) at baseline and 1 (5.0%) after the experience. Nevertheless, about 80% of the participants showed a high degree ofjob satisfaction, in terms of positive influence of job in the professional satisfaction and of clear satisfaction for the organization, during both evaluation. In respect to 2010, the number of organ donors and that of ocular tissue donors improved of about 16% and 10%, respectively, during the year of the project and in the following year (mean value). We recognize that our team-building project for personnel involved in the stressful and demanding setting of organ and tissue donation, worthwhile and recompensing at the same time, possibly influenced the personal commitment and the quality of job provided. The high level of stress showed by participants should be

  2. Functional performance, nutritional status, and body composition in ambulant community-dwelling individuals 1-3 years after suffering from a cerebral infarction or intracerebral bleeding.

    Science.gov (United States)

    Vahlberg, Birgit; Zetterberg, Lena; Lindmark, Birgitta; Hellström, Karin; Cederholm, Tommy

    2016-02-19

    Muscle wasting and obesity may complicate the post-stroke trajectory. We investigated the relationships between nutritional status, body composition, and mobility one to 3 years after stroke. Among 279 eligible home-dwelling individuals who had suffered a stroke (except for subarachnoid bleeding) 1-3 years earlier, 134 (74 ± 5 years, 69% men) were examined according to the Mini Nutritional Assessment-Short Form (MNA-SF, 0-14 points), including body mass index (BMI, kg/m(2)), body composition by bio-impedance analyses (Tanita BC-545), the Short Physical Performance Battery (SPPB, 0-12 points) combining walking speed, balance, and chair stand capacity, and the self-reported Physical Activity Scale for the Elderly (PASE). BMI ≥ 30 kg/m(2) was observed in 22% of cases, and 14% were at risk for malnutrition according to the MNA-SF. SPPB scores ≤ 8 in 28% of cases indicated high risk for disability. Mobility based on the SPPB was not associated with the fat-free mass index (FFMI) or fat mass index (FMI). Multivariate logistic regression indicated that low mobility, i.e., SPPB ≤ 8 points, was independently related to risk for malnutrition (OR 4.3, CI 1.7-10.5, P = 0.02), low physical activity (PASE) (OR 6.5, CI 2.0-21.2, P = 0.02), and high age (OR 0.36, CI 0.15-0.85, P = 0.02). Sarcopenia, defined as a reduced FFMI combined with SPPB scores ≤ 8 or reduced gait speed (sarcopenia with BMI > 30 kg/m(2). Nutritional disorders, i.e., obesity, sarcopenia, or risk for malnutrition, were observed in about one-third of individuals 1 year after stroke. Risk for malnutrition, self-reported physical activity, and age were related to mobility (SPPB), whereas fat-free mass (FFM) and fat mass (FM) were not. Nutrition and exercise treatment could be further evaluated as rehabilitation opportunities after stroke.

  3. Stock Status

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data inform the public of the most recent stock status for all stocks (FSSI and non-FSSI) in the fishery management unit contained in a fishery managment plan....

  4. Effects of Atenolol on Growth Performance, Mortality Due to Ascites, Antioxidant Status and Some Blood Parameters in Broilers under Induced Ascites

    Directory of Open Access Journals (Sweden)

    mokhtar fathi

    2016-11-01

    Full Text Available Introduction Broiler chickens are intensively selected for productive traits. The management of these highly productive animals must be optimal to allow their full genetic potential to be expressed. If this is not done, inefficient production and several metabolic diseases such as ascites become apparent. Investigations in mammals indicated that the b- adrenoreceptor characteristics are differentially regulated by chronic hypoxia and play an important role in the cardiovascular system. The density of b-adrenergic receptors was higher in cardiac cells of ascites sensitive birds compared with ascites-resistant ones. Moreover, the characteristics of b-adreno receptors are different in cardiac cells of birds with right ventricular hypertrophy and heart failure compared with healthy birds. Treatment with the selective b1-adrenoceptor blocker, atenolol, abolished right ventricular hypertrophy in response to hypoxia compared with normoxic condition in rats. Materials and Methods This study investigated the comparative effects of different levels of atenolol Growth performance, Mortality due to ascites, antioxidant status and blood parameters in broilers under induced ascites. Six hundred one-day-old male broilers (Ross 308 in a completely randomized experimental design with four treatments (Positive control, negative control, and two levels of 30 and 60 ppm atenolol with five replicates of thirty birds were applied. Birds in positive control were reared in natural temperature without atenolol, the other bird groups were reared in cold temperature with 0, 30 and 60 ppm atenolol. The average daily feed intake (ADFI, average daily weight gain (ADWG and feed conversion ratio (FCR for each group of birds were calculated and mortality was daily weighed, recorded and used to correct the FCR. Observations were made daily to record the incidence of ascites and mortality. Diagnosis of ascites generally depends on observation of the following symptoms: (1 right

  5. The effect of lemon grape and apple pulps on performance, carcass traits, digestive tract characteristic, intestinal morphology and immune status of broilers

    Directory of Open Access Journals (Sweden)

    kivan Sadighi

    2016-04-01

    Full Text Available Introduction Iran has good condition in fruit production among all countries in the world. Lemon, grape and apple are fruits that are produced in large scale in our country. For economical use of these fruits, there are different factories which produce fruit juices. Pulps are the main waste that remain after juicing fruits. Pulps contain some nutrients such as vitamins and minerals and secondary substances, also in contrast to common diets ingredients, there are very cheap and using them in diets may reduce the production price. As pulps contain high level of fiber, can be easily used without any adverse effects in ruminant, but in poultry, especially in broilers using higher level of pulps may be not possible. However, using low level of pulps do not have any adverse effects on performance and blood parameters and can improve the meat quality and blood biochemical and immune parameters. Moreover discharge of these wastes to environment can cause serious environmental problems. This experiment was conducted to evaluate the effects of lemon, grape and apple pulps on performance, carcass traits, digestive tract characteristic, intestinal morphology and immune status of broilers. Materials and Methods In this experiment 240 Ross-308 broilers were used in 5 treatments, 4 replicates and 12 chicks in each replicate in a completely randomized design. Experimental groups included: 1 control group (without using pulp, 2 group with 150 mg/kg vitamin E (as positive control group, 3 group with 3% lemon pulp, 4 group with 3% grape pulp, 5 group with 3% apple pulp. Grower diets from 11 to 24 days and finisher diets from 25 to 42 days were used by broilers. In the experimental periods all chickens in experimental groups had free accsess to feed and water. The lighting program included: 23 h light and 1 h darkness in all the experimental period.Feed intake and weight gain were measured at the end of growing and finishing and whole periods. Feed conversion

  6. Status of industrial pollution and their effect on seed germination and growth performance of albizia lebbek (benth.) and leucaena leucocephala (LAM) de wit

    International Nuclear Information System (INIS)

    Shiuli, M.D.; Alam, S.; Mohiuddin, M.M.

    2005-01-01

    Pollution status of the effluents from three different industries viz. tanneries, fisheries and textiles, grown in the vicinity of the Karnafully River, Chittagong, Bangladesh and their influence on soil, seed germination and plant growth have been studied. The effluents pollute the adjacent water bodies and soils. The effluents from the tanneries are much more polluted than that of effluents from textiles and fisheries. This is due to the accumulation more total solids (1779 mg/l) as compared to that of 539 mg/l and 466 mg/l in textiles and fisheries effluents respectively and thus Chloride (3962 mg/i), Sulfate (450 mg/l) and Nitrate (7.03 mg/l), eventually showed similar trend. In addition to that, some of the pollution related parameters were dominant in the effluents of both textiles ( Turbidity- 177.9 NTU, SS- 23.27 ml/l, D.O.- 3.0 mg/l, COD- 8480 mg/l, BOD- 1860 mg/l Phosphate- 9.38 mg/l) and fisheries (D.O. -2.5 mg/l) than that of the tanneries (Turbidity- 57.6 NTU, SS- 18. 9 ml/l, D.O.- 1.2 mg/l, COD- 7529 mg/i, BOD- 1653 mg/l , Phosphate- 7.28 mg/l). Irrespective of physical or chemical composition most of the effluents were simply unusable. From the analysis of soil it was detected that the pH of soil samples contaminated with effluents was almost similar (6.7, 6.6 and 6.3, respectively) to that of control (6.2), but the concentration of organic matter, N, P, K and S in soil samples contaminated with the industrial effluents of tanneries (OM-4.5%, N- 0.227%, P- 108.21 micro gram/gram and K - 0.22 m eq/100 g), Fisheries (OM-4.0%, N- 0.4%, P-74.71 micro gram/gram, and K- 0.23 meq/100 g) and Textile (OM- 3.4%, N- 0.167%, P- 120 micro g/gram and K- 0.5 meq/100 g) were significantly higher than that of control samples (OM- 2.0%, N-0.24%, P- 50 micro g/g and k-0.15 meq/100g). Adverse effect of contamination, height growth, collar diameter, total biomass and nodule production of Albizia lebbek were 67% , 18.62 cm, 4 cm, 10.2 gm and 59 in soil without any

  7. Effect of serum calcium status at calving on survival, health, and performance of postpartum Holstein cows and calves under certified organic management.

    Science.gov (United States)

    Wilhelm, A L; Maquivar, M G; Bas, S; Brick, T A; Weiss, W P; Bothe, H; Velez, J S; Schuenemann, G M

    2017-04-01

    The study objective was to assess the effect of hypocalcemia (HYPO; ≤2.0 mmol/L) of the dam at calving on survival, health, and performance of lactating dairy cows and their calves under certified organic management. Prepartum dairy cows (primiparous, n = 445; multiparous, n = 328) from 1 dairy herd were monitored (prepartum pen) for imminent signs of parturition (appearance of amniotic sac outside the vulva) until birth. All calves were subject to the same newborn care, colostrum management, and failure of passive transfer assessment (serum total protein ≤5.5 mg/dL). Serum total calcium of cows was determined in samples taken within 2 h after calving. To define HYPO cows after calving, a cut-point of total serum Ca concentration with optimal sensitivity and specificity to predict metritis or calf diarrhea was established by using the receiver operator characteristic. The effect of HYPO on survival (died or culled within 60 DIM), health status, and pregnancy per artificial insemination (PAI) for first services of lactating cows were analyzed using the GLIMMIX procedure of SAS. Additionally, the effect of HYPO at calving on days in milk (DIM) at first service (DIMFS), milk yield (kg), milk components (percent fat and protein), and somatic cell count were analyzed for the first 3 Dairy Herd Improvement Association (DHIA) tests using the MIXED procedure of SAS (SAS Institute Inc., Cary, NC). The effect of parity (primiparous and multiparous), body condition score at calving, and manure hygiene score at calving were also included in the statistical models. The effect of HYPO at calving on calf survival, serum total protein, and diarrhea within 10 d of age were assessed using GLIMMIX procedure of SAS. The overall prevalence of HYPO was 14.6% (2.7% for primiparous and 30.8% for multiparous cows). Cows experiencing HYPO at calving had greater proportion of metritis (25.1 vs. 14.7%) and culling within 60 DIM (15.9 vs. 6.8%) compared with non-HYPO cows, respectively

  8. The association between collateral status, recanalization and long term outcome in stroke patients treated with stent retrievers - Are there indications not to perform thrombectomy based on CT angiography?

    Science.gov (United States)

    Nordmeyer, Hannes; Webering, Nadine; Chapot, Rene; Hadisurya, Jeffrie; Heddier, Markus; Stracke, Paul; Berger, Klaus; Isenmann, Stefan; Weber, Ralph

    2017-06-01

    To investigate the association between baseline pial collateral status on computed tomography angiography (CTA) with recanalization and functional outcome in patients with acute anterior circulation stroke treated with stent retriever thrombectomy. Retrospective analysis of 87 patients from a prospective thrombectomy registry. Collateral status on CTA source images was categorized into good, moderate, and poor with the Tan and Miteff scores by two-blinded readers. Association between CTA collateral status and successful recanalization was investigated with univariate regression analysis. Multivariate logistic regression was used to analyse the association between collateral score and favourable clinical outcome (mRS 0-2) and death at follow-up. Mean age was 72.5 years and baseline median NIHSS score was 15. Patients with poor collaterals on Tan score had a significant higher mortality compared with moderate or good collaterals during a mean follow-up period of 5.2 months (85.7% vs. 30.6% vs. 25.7%, Pcollateral score could be assessed only in 65 of the 87 patients and the Tan collateral score had a higher interrater reliability. Poor collaterals on CTA were associated with a very high rate of fatal outcome in anterior circulation stroke patients despite a high rate of successful recanalization with stent retrievers. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  9. Arachidonic acid and DHA status in pregnant women is not associated with cognitive performance of their children at 4 or 6-7 years.

    Science.gov (United States)

    Crozier, Sarah R; Sibbons, Charlene M; Fisk, Helena L; Godfrey, Keith M; Calder, Philip C; Gale, Catharine R; Robinson, Sian M; Inskip, Hazel M; Baird, Janis; Harvey, Nicholas C; Cooper, Cyrus; Burdge, Graham C

    2018-06-01

    Arachidonic acid (ARA) and DHA, supplied primarily from the mother, are required for early development of the central nervous system. Thus, variations in maternal ARA or DHA status may modify neurocognitive development. We investigated the relationship between maternal ARA and DHA status in early (11·7 weeks) or late (34·5 weeks) pregnancy on neurocognitive function at the age of 4 years or 6-7 years in 724 mother-child pairs from the Southampton Women's Survey cohort. Plasma phosphatidylcholine fatty acid composition was measured in early and late pregnancy. ARA concentration in early pregnancy predicted 13 % of the variation in ARA concentration in late pregnancy (β=0·36, PDHA concentration in early pregnancy predicted 21 % of the variation in DHA concentration in late pregnancy (β=0·46, PDHA nor ARA concentrations in early or late pregnancy were associated significantly with neurocognitive function in children at the age of 4 years or the age of 6-7 years. These findings suggest that ARA and DHA status during pregnancy in the range found in this cohort are unlikely to have major influences on neurocognitive function in healthy children.

  10. Behavior, Expectations and Status

    Science.gov (United States)

    Webster, Jr, Murray; Rashotte, Lisa Slattery

    2010-01-01

    We predict effects of behavior patterns and status on performance expectations and group inequality using an integrated theory developed by Fisek, Berger and Norman (1991). We next test those predictions using new experimental techniques we developed to control behavior patterns as independent variables. In a 10-condition experiment, predictions…

  11. COMPASS Status Report 2010

    CERN Document Server

    COMPASS Collaboration

    2010-01-01

    This report gives an overview of the setup and the performance of the COMPASS experiment during the 2009 hadron beam run and describes the preparation and startup of the 2010 muon beam run with the polarised target. The status of analysis is presented both for the hadron and muon data with emphasis on the 2008/2009 hadron data.

  12. NASA Armstrong Status

    Science.gov (United States)

    Jacobson, Steven R.

    2014-01-01

    Armstrong (formerly Dryden) Flight Research Center continues it's legacy of exciting work in the area of dynamics and control of advanced vehicle concepts. This status presentation highlights the research and technology development that Armstrong's Control and Dynamics branch is performing in the areas of Control of Flexible Structures and Automated Cooperative Trajectories.

  13. Compliance status

    International Nuclear Information System (INIS)

    Black, D.G.

    1995-01-01

    This section of the 1994 Hanford Site Environmental Report summarizes the activities conducted to ensure that the Hanford Site is in compliance with federal environmental protection statutes and related Washington State and local environmental protection regulations and the status of Hanford's compliance with these requirements. Environmental permits required under the environmental protection regulations are discussed under the applicable statute

  14. Compliance status

    Energy Technology Data Exchange (ETDEWEB)

    Black, D.G.

    1995-06-01

    This section of the 1994 Hanford Site Environmental Report summarizes the activities conducted to ensure that the Hanford Site is in compliance with federal environmental protection statutes and related Washington State and local environmental protection regulations and the status of Hanford`s compliance with these requirements. Environmental permits required under the environmental protection regulations are discussed under the applicable statute.

  15. STATUS REPORT

    Indian Academy of Sciences (India)

    First page Back Continue Last page Graphics. STATUS REPORT. Raman scattering observed – 90, 135, 180 degrees and back scattering. Traditionally specific angle dependence to learn about polarization response. Learn molecular information from the surface or materials just below the surface (upto 12 mm depth) ...

  16. Differences in cognitive performance, level of dependency and quality of life (QoL), related to age and cognitive status in a sample of Spanish old adults under and over 80 years of age.

    Science.gov (United States)

    Calero, Dolores; Navarro, Elena

    2011-01-01

    The main objective of this study was to analyze the similarities and differences in cognitive performance, level of dependency, cognitive plasticity and QoL in a sample of young-old adults and old-old adults, bearing in mind both the age-group (under or over 80 years) and the cognitive status of the participants. The study population consisted of 220 people living in sheltered accommodation for elderly people in the South of Spain, with an average age of 80.75 years. Participants were evaluated by means of cognitive performance tests, a QoL questionnaire, a depression scale and a dependency assessment scale. The results indicate that the main differences in the variables analyzed are due to the cognitive status of the sample and not to the fact that the participants are under or over 80 years of age. The findings show that major inter-individual differences in this stage of life depend not only on age but also on cognitive status, which is thus an important factor to take into account when working with this sector of the population. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  17. The U.S. Department of Energy Laboratory Accreditation Program for testing the performance of extremity dosimetry systems: a summary of the program status

    International Nuclear Information System (INIS)

    Cummings, F.M.; Carlson, R.D.; Gesell, T.F.; Loesch, R.M.

    1992-01-01

    In 1986, The U.S. Department of Energy (DOE) implemented a program to test the performance of its personnel whole-body dosimetry systems. This program was the DOE Laboratory Accreditation Program (DOELAP). The program parallels the performance testing program specified in the American National Standard for Dosimetry - Personnel Dosimetry Performance -Criteria for Testing (ANSI N13.11-1983), but also addresses the additional dosimetry needs of DOE facilities. As an extension of the whole-body performance testing program, the DOE is now developing a program to test the performance of personnel extremity dosimetry systems. The draft DOE standard for testing extremity dosimetry systems is much less complex than the whole-body dosimetry standard and reflects the limitations imposed on extremity dosimetry by dosimeter design and irradiation geometry. A pilot performance test session has been conducted to evaluate the proposed performance-testing standard. (author)

  18. Impact of iron on the performance of clay barriers in waste disposal systems. Report on the status of research and development

    International Nuclear Information System (INIS)

    Wersin, Paul; Snellman, Margit

    2008-05-01

    The interaction of iron components with swelling clay materials in the EBS has received relatively little attention so far in safety assessment studies. It is however widely recognised that such interaction processes (e.g. corrosion, mineral alteration) need to be considered since they have the potential to impair repository long-term safety. A workshop on this topic was held in 2006 in Basel and has shed some light on the current status and the remaining uncertainties of relevance for safety purposes. Also, the workshop highlighted that there is strong interest to continue research in this field. Notably, waste management organisations from France (Finland), Japan, Sweden and Switzerland showed interest to exchange information in this research area on a regular basis and, if possible, advance common projects. Following this workshop, it was decided by Posiva, SKB and Nagra to compile the status of research and development based on a pre-formatted questionnaire sent out to a number of research organisations. This report summarises the information obtained. This serves to identify the remaining knowledge gaps and to explore areas of common interest. Some ideas for common research studies and possibilities how to organise these are presented

  19. Impact of iron on the performance of clay barriers in waste disposal systems. Report on the status of research and development

    Energy Technology Data Exchange (ETDEWEB)

    Wersin, Paul (National Cooperative for the Disposal of Radioactive Waste, Nagra, Wettingen (Switzerland)); Snellman, Margit (Saanio and Riekkola Oy, Helsinki (Finland))

    2008-05-15

    The interaction of iron components with swelling clay materials in the EBS has received relatively little attention so far in safety assessment studies. It is however widely recognised that such interaction processes (e.g. corrosion, mineral alteration) need to be considered since they have the potential to impair repository long-term safety. A workshop on this topic was held in 2006 in Basel and has shed some light on the current status and the remaining uncertainties of relevance for safety purposes. Also, the workshop highlighted that there is strong interest to continue research in this field. Notably, waste management organisations from France (Finland), Japan, Sweden and Switzerland showed interest to exchange information in this research area on a regular basis and, if possible, advance common projects. Following this workshop, it was decided by Posiva, SKB and Nagra to compile the status of research and development based on a pre-formatted questionnaire sent out to a number of research organisations. This report summarises the information obtained. This serves to identify the remaining knowledge gaps and to explore areas of common interest. Some ideas for common research studies and possibilities how to organise these are presented

  20. Wyniki ekonomiczne klubów sportowych o statusie pożytku publicznego w Polsce = Economic performance of sports clubs charitable status in Poland

    Directory of Open Access Journals (Sweden)

    Artur Wyszyński

    2015-11-01

    Abstract The main aim of this article is to assess the financial condition and results of Polish football clubs who have the status of public benefit organizations (OPP. The analysis was conducted for clubs that were played matches in the 2013/2014 season in the men's football tournament at all levels except the highest such competitions. Ekstraklasa (no clubs having the status OPP for levels I, II, III, IV league and class district, A , B and C. All the clubs analyzed as a function of the association. The analysis shows that clubs are in a bad financial situation. Most clubs, regardless of the grade level in which the matches were played were characterized by a low value of wealth. Average debt was close to 100%. As a result, nearly one-third of the clubs showed a negative equity value. About half of the clubs observed a negative value total return on assets and return on sales. In the structure of revenues are the primary source of public funds. Other sources of income included clubs, private funds, other and income from the 1% tax on individuals.   Key words: club sports, financial analysis, income football clubs [1] e-mail artur.wyszynski@uwm.edu.pl

  1. Status Epilepticus

    Science.gov (United States)

    Seinfeld, Syndi; Goodkin, Howard P.; Shinnar, Shlomo

    2016-01-01

    Although the majority of seizures are brief and cause no long-term consequences, a subset is sufficiently prolonged that long-term consequences can result. These very prolonged seizures are termed “status epilepticus” (SE) and are considered a neurological emergency. The clinical presentation of SE can be diverse. SE can occur at any age but most commonly occurs in the very young and the very old. There are numerous studies on SE in animals in which the pathophysiology, medication responses, and pathology can be rigorously studied in a controlled fashion. Human data are consistent with the animal data. In particular, febrile status epilepticus (FSE), a form of SE common in young children, is associated with injury to the hippocampus and subsequent temporal lobe epilepsy (TLE) in both animals and humans. PMID:26931807

  2. 25-hydroxyvitamin D status and change in physical performance and strength in older adults : the Health, Aging, and Body Composition Study

    NARCIS (Netherlands)

    Houston, Denise K; Tooze, Janet A; Neiberg, Rebecca H; Hausman, Dorothy B; Johnson, Mary Ann; Cauley, Jane A; Bauer, Doug C; Cawthon, Peggy M; Shea, M Kyla; Schwartz, Gary G; Williamson, Jeff D; Tylavsky, Frances A; Visser, Marjolein; Simonsick, Eleanor M; Harris, Tamara B; Kritchevsky, Stephen B

    2012-01-01

    Low 25-hydroxyvitamin D (25(OH)D) concentrations are common among older adults and are associated with poorer physical performance and strength, but results from longitudinal studies have been inconsistent. The 25(OH)D threshold for physical performance and strength was determined, and both

  3. Rethinking status dystonicus.

    Science.gov (United States)

    Ruiz-Lopez, Marta; Fasano, Alfonso

    2017-12-01

    Status dystonicus is a movement disorder emergency that has been a source of controversy in terms of terminology, phenomenology, and management since it was first described in 1982. Here we argue that the current use of the term status dystonicus falls well short of the precision needed for either clinical or academic use. We performed a critical review on this topic, describing possible pathophysiological mechanisms and areas of uncertainties. This review also addresses the problems derived by the extreme clinical heterogeneity of this condition, as the lack of an objective criterion useful for the definition, or the fact that status dystonicus may present not only in the context of a known dystonic syndrome. We propose a new possible definition that includes not only dystonia but also other hyperkinetic movements in the wide range of movement disorders that can be seen during an episode. The new definition keeps the term status dystonicus and highlights the fact that this is a medical emergency based on the impairment of bulbar and/or respiratory function requiring hospital admission as the principal feature. Furthermore, the new definition should not consider as necessary unspecific features as patient's condition at baseline, the distribution of dystonia, occurrence of systemic symptoms such as fever or laboratory findings. We hope that this proposal will stimulate the debate on this subject among our peers, further developing a clinical and pathophysiological understanding of status dystonicus. © 2017 International Parkinson and Movement Disorder Society. © 2017 International Parkinson and Movement Disorder Society.

  4. Associations of vitamin D status, bone health and anthropometry, with gross motor development and performance of school-aged Indian children who were born at term with low birth weight

    Science.gov (United States)

    Filteau, Suzanne; Rehman, Andrea M; Yousafzai, Aisha; Chugh, Reema; Kaur, Manpreet; Sachdev, H P S; Trilok-Kumar, Geeta

    2016-01-01

    Objectives There is little information regarding motor development of children born at term with low birth weight (LBW), a group that constitutes a large proportion of children in South Asia. We used data from infancy and at school age from a LBW cohort to investigate children's motor performance using causal inference. Design Cross-sectional follow-up study. Setting Delhi, India. Participants We recruited 912 children aged 5 years who had participated in a trial of vitamin D for term LBW infants in the first 6 months of life. Outcome measures We focused on gross motor development, using the Ages and Stages Questionnaire (ASQ) gross motor scale and several measures of motor performance. We examined the effects on these of current anthropometry, vitamin D status and bone health, controlling for age, sex, season of interview, socioeconomic variables, early growth, recent morbidity, sun exposure and animal food intake. Results In adjusted analyses, stunted children (height-for-age Z (HAZ) squats in 15 s. Poorer vitamin D status was associated with the ability to perform more stands and squats. Lower tibia ultrasound Z score was associated with greater hand grip strength. Early growth and current body mass index had no associations with motor outcomes. Conclusions Current HAZ and arm muscle area showed the strongest associations with gross motor outcomes, likely due to a combination of simple physics and factors associated with stunting. The counterintuitive inverse associations of tibia health and vitamin D status with outcomes may require further research. PMID:26747034

  5. Inferior vena cava/aorta diameter index in the assessment of the body fluid status – a comparative study of measurements performed by experienced and inexperienced examiners in a group of young adults

    Directory of Open Access Journals (Sweden)

    Kaja Durajska

    2014-09-01

    Full Text Available The assessment of the body fluid status is one the most challenging tasks in clinical practice. Although there are many methods to assess the body fluid status of patients, none of them is fully satisfactory in contemporary medical sciences. In the article below, we compare the results of measurements performed by experienced and inexperienced examiners based on the inferior vena cava/aorta diameter index in a sonographic hydration assessment. The study enrolled 50 young students at the age of 19–26 (the median age was 22.95 including 27 women and 23 men. The volunteers were examined in the supine position with GE Logiq 7 system and a convex transducer with the frequency of 2–5 MHz. The measurements were performed in the longitudinal and transverse planes by two inexperienced examiners – the authors of this paper, following a four-hour training conducted by an experienced sonographer. The longitudinal values of the inferior vena cava/aorta diameter index obtained in this study were similar to those found in the literature. The reference value for the inferior vena cava/aorta index determined by Kosiak et al., which constituted 1.2 ± 2 SD, for SD = 0.17, was similar to the values obtained by the authors of this paper which equaled 1.2286 ± 2 SD, for SD = 0.2. The article presented below proves that measuring the inferior vena cava/aorta diameter index is not a complex examination and it may be performed by physicians with no sonographic experience. Furthermore, the paper demonstrates that the inferior vena cava/aorta diameter index measured in the transverse plane is similar to the inferior vena cava/aorta diameter index determined in the longitudinal plane. Thus, both measurements may be used interchangeably to assess the hydration status of patients.

  6. Assessment of Mental Status.

    Science.gov (United States)

    Finney, Glen R; Minagar, Alireza; Heilman, Kenneth M

    2016-02-01

    Assessing the mental status of patients with a neurobehavioral disorder is a critical element in the diagnosis and treatment of these patients. This assessment should always be performed after the patient's history it taken and a general physical as well as a neurologic examination is completed. The mental status examination commences with observing the patient's appearance and level of consciousness. The examiner should also pay attention to patient's social behavior, emotional state and mood. There are 3 major means of assessing a patient's mental status. One type attempts to determine if the patient is demented and the severity of the dementia as it pertains to their ability to perform activities of daily living as well as instrumental activities. A second type of assessment utilizes what may be termed as "screening tests" or "omnibus tests". These brief tests are performed independent of the patient's history and examination. The two most frequently used screening tests are the Mini-Mental Status Examination (MMSE) and the Montreal Cognitive Assessment (MoCA). The third means of assessing a patient's mental status is by using specific neuropsychological tests that focus on specific domains of cognition, such as frontal executive functions, attention, episodic verbal and visuospatial memory, declarative knowledge such as language (speech, reading and writing) and arithmetical, as well as visuospatial and perceptual abilities. These neurobehavioral, neuropsychiatric and neuropsychological assessments of patients with a cognitive decline and behavioral abnormalities should often be accompanied by laboratory tests, and neuroimaging that can help determine the underlying pathologic process so that effective therapeutic and management approaches can be provided. Copyright © 2016 Elsevier Inc. All rights reserved.

  7. CMS Status

    International Nuclear Information System (INIS)

    Dobrzynski, L.

    2007-01-01

    The status of the construction and installation of CMS detector is reviewed. The 4T magnet is cold since end of February 2006. Its commissioning up to the nominal field started in July 2006 allowing a Cosmic Challenge in which elements of the final detector are involved. All big mechanical pieces equipped with muons chambers have been assembled in the surface hall SX5. Since mid July the detector is closed with commissioned HCAL, two ECAL supermodules and representative elements of the silicon tracker. The trigger system as well as the DAQ are tested. After the achievement of the physics TDR, CMS is now ready for the promising signal hunting. (author)

  8. Radiological status of the environment around the site of Saint-Pierre (Cantal). IRSN Third-party expertise. Part 1: situational analysis and additional studies to be performed

    International Nuclear Information System (INIS)

    2006-01-01

    This document reports the first part of a study which aimed at verifying the relevance of available studies and measurements for the Saint-Pierre ancient mining site and regarding risks related to radioactivity. More specifically, this study aimed at defining the most precisely as possible the perimeter of potential influence of this site for three pollution vectors (water, air, soils) with respect to available studies and in terms of necessary additional studies, at assessing the radiological impact on populations living, working or staying at the neighbourhood of this restored site, and at proposing an evolution of the current survey arrangement in order to make it more adapted and reliable. This first part is dedicated to the analysis of all existing documents in order to define required additional elements (analysis, sampling, surveys, and so on) for a better knowledge of the present radiological status of the studied site. After a presentation of the physical and human characteristics of the site, and of its geological and mineralogical context, and recalled the past mining activities (extraction, processing, wastes, waste rock and tailings), the report proposes an analysis per component: external exposure, radon and dusts, underground waters, surface waters, sediments, aquatic fauna and flora, food products. An assessment and recommendations are formulated. Financial aspects are discussed

  9. Physical Performance and Serum 25(OH)vitamin D Status in Community Dwelling Old Mobility Limited Adults: A Cross-Sectional Study.

    Science.gov (United States)

    von Berens, Å; Cederholm, T; Fielding, R A; Gustafsson, T; Kirn, D; Laussen, J; Nydahl, M; Travison, T G; Reid, K; Koochek, A

    2018-01-01

    To examine the potential association between serum 25(OH) vitamin D and the performance on the Short Physical Performance Battery (SPPB) including the sub-components; five repeated chair stands test, 4 meters walk test and balance in older mobility-limited community-dwelling men and women. A cross sectional study was performed in American and Swedish subjects who were examined for potential participation in a combined exercise and nutrition intervention trial. Logistic regression analysis and linear regression analyses were performed to evaluate the association for 25(OH)D with the overall score on the SBBP, chair stand, gait speed and balance. Community-dwelling (mean age 77.6 ± 5.3 years) mobility limited American (n=494) and Swedish (n=116) females (59%) and males. The SPPB (0-12 points) includes chair stand (s), gait speed (m/s) and a balance test. Mobility limitation i.e., SPPB score ≤ 9 was an inclusion criterion. A blood sample was obtained to measure serum 25(OH)vitamin D concentrations. No clear association of 25(OH)D with SPPB scores was detected either when 25(OH)D was assessed as a continuous variable or when categorized according to serum concentrations of <50, 50-75 or <75 nmol/L. However, when analyzing the relationship between 25(OH)D and seconds to perform the chair stands, a significant quadratic relationship was observed. Thus, at serum levels of 25(OH)D above 74 nmol/L, higher concentrations appeared to be advantageous for the chair stand test, whereas for serum levels below 74 nmol/L this association was not observed. This cross- sectional study lacked clear association between serum 25(OH)D and physical performance in mobility limited adults. A potentially interesting observation was that at higher serum levels of 25(OH)D a better performance on the chair stand test was indicated.

  10. Association of nutritional status and functional capacity in gastrointestinal cancer patients.

    Science.gov (United States)

    Pérez-Cruz, Elizabeth; Camacho-Limas, Christian Patricio

    To determine the nutritional status and its association with functional capacity in patients with digestive tract cancer. We retrospectively studied all adult patients hospitalized who were diagnosed as having a cancer of the digestive tract. Nutritional status and functional capacity were assessed. Descriptive statistic and odds ratio were used to determine the association in SPSS 14.0. 57 patients were included, 96% had weight loss. Using subjective global assessment (SGA) as a method of screening, 82.5% of the patients were found malnutrition and by biochemical and immunological test 82% and 65% respectively. Functional capacity was assessed by Karnofsky index, finding that 75.5% of the patients have some activity limitation. Results show an association between malnutrition by SGA and limitation in functional capacity (c2 = 1.56; p = 0.212; OR: 2.46; 95% confidence interval [95% CI]: 0.581-10.465). In addition, we observe an association between the total lymphocyte count and limitation in functional capacity (χ2 = 6.94; p = 0.008; OR: 5.23; 95% CI: 1.441-19.025). Malnutrition in patients with digestive tract cancer was associated with limitation in functional capacity. Copyright: © 2017 SecretarÍa de Salud

  11. Automatic examination of nuclear reactor vessels with focused search units. Status and typical application to inspections performed in accordance with ASME code

    International Nuclear Information System (INIS)

    Verger, B.; Saglio, R.

    1981-05-01

    The use of focused search units in nuclear reactor vessel examinations has significantly increased the capability of flaw indication detection and characterization. These search units especially allow a more accurate sizing of indications and a more efficient follow up of their history. In this aspect, they are a unique tool in the area of safety and reliability of installations. It was this type of search unit which was adopted to perform the examinations required within the scope of inservice inspections of all P.W.R. reactors of the French nuclear program. This paper summarizes the results gathered through the 4l examinations performed over the last five years. A typical application of focused search units in automated inspections performed in accordance with ASME code requirements on P.W.R. nuclear reactor vessels is then described

  12. Ch-Ch-Ch-changes: how action phase functional leadership, team human capital, and interim vs. permanent leader status impact post-transition team performance

    OpenAIRE

    Maynard, M. Travis; Resick, Christian J.; Cunningham, Quinn W.; DiRenzo, Marco S.

    2017-01-01

    The article of record as published may be found at http://dx.doi.org/10.1007/s10869-016-9482-5 This study addresses the following: (1) does a team leader change along with the quality of the team’s human capital affect post-change team performance?; (2) is functional leadership of the team’s human capital a driver of post-change team performance?; and (3) should interim vs. permanent leaders manage the team’s human capital differently? We analyzed archival data from Major League Baseba...

  13. Evaluation of lymph node status after neoadjuvant chemotherapy in breast cancer patients: comparison of diagnostic performance of ultrasound, MRI and ¹⁸F-FDG PET/CT.

    Science.gov (United States)

    You, S; Kang, D K; Jung, Y S; An, Y-S; Jeon, G S; Kim, T H

    2015-08-01

    To evaluate the diagnostic performance of ultrasound, MRI and fluorine-18 fludeoxyglucose positron emission tomography (¹⁸F-FDG PET)/CT for the diagnosis of metastatic axillary lymph node (ALN) after neoadjuvant chemotherapy (NAC) and to find out histopathological factors affecting the diagnostic performance of these imaging modalities. From January 2012 to November 2014, 191 consecutive patients with breast cancer who underwent NAC before surgery were retrospectively reviewed. We included 139 patients with ALN metastasis that was confirmed on fine needle aspiration or core needle biopsy at initial diagnosis. After NAC, 39 (28%) patients showed negative conversion of ALN on surgical specimens of sentinel lymph node (LN) or ALN. The sensitivity of ultrasound, MRI and PET/CT was 50% (48/96), 72% (70/97) and 22% (16/73), respectively. The specificity of ultrasound, MRI and PET/CT was 77% (30/39), 54% (21/39) and 85% (22/26), respectively. The Az value of combination of ultrasound and PET/CT was the highest (0.634) followed by ultrasound (0.626) and combination of ultrasound, MRI and PET/CT (0.617). The size of tumour deposit in LN and oestrogen receptor was significantly associated with the diagnostic performance of ultrasound (p performance of PET/CT (p = 0.023, p = 0.002, p = 0.036, p = 0.044 and p = 0.008, respectively). On multivariate logistic regression analysis, size of tumour deposit within LN was identified as being independently associated with diagnostic performance of ultrasound [odds ratio, 13.07; 95% confidence interval (CI), 2.95-57.96] and PET/CT (odds ratio, 6.47; 95% CI, 1.407-29.737). Combination of three imaging modalities showed the highest sensitivity, and PET/CT showed the highest specificity for the evaluation of ALN metastasis after NAC. Ultrasound alone or combination of ultrasound and PET/CT showed the highest positive-predictive value. The size of tumour deposit within ALN was significantly associated with

  14. The status of GALLEX

    International Nuclear Information System (INIS)

    Cribier, M.

    1990-01-01

    The present status of the Gallium Solar Neutrino Experiment performed by the GALLEX Collaboration in the Gran Sasso Underground Laboratory is described. The implementation phase of this experiment is now completed, the whole gallium is at hand and data taking starts now. After a short introduction and an outline of the basic experimental procedure, details will be given on different parts of the experiment and on some background. 14 refs., 2 figs

  15. Dietary Supplementation of Benzoic Acid and Essential Oil Compounds Affects Buffering Capacity of the Feeds, Performance of Turkey Poults and Their Antioxidant Status, pH in the Digestive Tract, Intestinal Microbiota and Morphology

    Directory of Open Access Journals (Sweden)

    I. Giannenas

    2014-02-01

    Full Text Available Three trials were conducted to evaluate the effect of supplementation of a basal diet with benzoic acid or thymol or a mixture of essential oil blends (MEO or a combination of benzoic acid with MEO (BMEO on growth performance of turkey poults. Control groups were fed a basal diet. In trial 1, benzoic acid was supplied at levels of 300 and 1,000 mg/kg. In trial 2, thymol or the MEO were supplied at levels of 30 mg/kg. In trial 3, the combination of benzoic acid with MEO was evaluated. Benzoic acid, MEO and BMEO improved performance, increased lactic acid bacteria populations and decreased coliform bacteria in the caeca. Thymol, MEO and BMEO improved antioxidant status of turkeys. Benzoic acid and BMEO reduced the buffering capacity compared to control feed and the pH values of the caecal content. Benzoic acid and EOs may be suggested as an effective alternative to AGP in turkeys.

  16. The effect of direct-fed microbial supplementation, as an alternative to antibiotics, on growth performance, intestinal immune status and epithelial barrier protein expression in broiler chickens

    Science.gov (United States)

    The objective of this study was to investigate the effects of Bacillus subtilis-based probiotic supplementation in broiler chicken diets on growth performance, feed efficiency, intestinal cytokine and tight junction (TJ) protein mRNA expression. Day-old broiler chicks (n = 140) were randomly assigne...

  17. The effects of direct-fed microbial supplementation, as alternative to antibiotics, on growth performance, intestinal immune status and epithelial barrier protein expression in broiler chickens

    Science.gov (United States)

    This study was conducted to investigate the effects of Bacillus subtilis supplementation in broiler chicken diets on growth performance, feed efficiency, intestinal cytokine and tight junction (TJ) protein mRNA expression. Day-old broiler chicks (n = 140) were assigned five dietary treatments: basal...

  18. Annual Status Report (FY2015) Performance Assessment for the Disposal of Low-Level Waste in the 200 West Area Burial Grounds

    Energy Technology Data Exchange (ETDEWEB)

    Khaleel, R. [INTERA, Inc., Austin, TX (United States); Mehta, S. [CH2M Hill Plateau Remediation Company, Richland, WA (United States); Nichols, W. E. [CH2M Hill Plateau Remediation Company, Richland, WA (United States)

    2016-02-01

    This annual review provides the projected dose estimates of radionuclide inventories disposed in the active 200 West Area Low-Level Burial Grounds (LLBGs) since September 26, 1988. These estimates area calculated using the original does methodology developed in the performance assessment (PA) analysis (WHC-EP-0645).

  19. Status Configurations, Military Service and Higher Education

    Science.gov (United States)

    Wang, Lin; Elder, Glen H., Jr.; Spence, Naomi J.

    2012-01-01

    The U.S. Armed Forces offer educational and training benefits as incentives for service. This study investigates the influence of status configurations on military enlistment and their link to greater educational opportunity. Three statuses (socioeconomic status of origin, cognitive ability and academic performance) have particular relevance for…

  20. NUTRITION AND HEALTH STATUS AND COGNITIVE PERFORMANCE OF SCHOOL CHILDREN IN JAKARTA AND TANGERANG RECEIVING WORLD FOOD PROGRAM – NUTRITION REHABILITATION PROGRAMME (WFP-NRP

    Directory of Open Access Journals (Sweden)

    Siti Muslimatun

    2014-09-01

    Full Text Available UN World Food Programme (WFPmelalui Nutrition Rehabilitation Programme (NRPmelakukan inisiasi pemberian makanan tambahan pada anak sekolah tahun 2004 dengan mendistribusikan biskuit yang difortikasi 9 vitamin dan 4 mineral di sekolah dasar di lingkungan penduduk miskin di Jakarta dan Tangerang. Untuk menilai dampak dari program ini dilakukan evaluasi perubahan status gizi dan kesehatan dan juga pengaruhnya pada asupan gizi serta kognitif dari anak setelah satu tahun pelaksanaan program. Data dari 691 anak (335 laki-laki, 356 perempuan diperoleh dari  Jakarta  Barat  (N=243,  Kota  Tangerang  (N=81  dan  Kabupaten Tangerang  (N=367. Sebagian anak merasakan lapar pada waktu sekolah dan lebih dari 80% sangat senang untuk mendapat  biscuit  setiap  hari.  Ditemukan  70%  anak  dapat  menghabiskan  1  pak,  20%  anak menghabiskan ½-1 pak, 10% <½ pack pak biskuit dengan asupan zat besi, zink, kalsium dan vitamin yang lebih tinggi dari biasanya. Dibanding dengan data dasar, terlihat terjadi penurunan prevalensi anemia dari 23,9% menjadi 10% dan cadangan besi yang rendah dari 25,7% menjadi 19,6%, serta untuk anak-anak di kabupaten Tangerang berkurangnya keluhan sakit. Nilai rata-rata kognitif anak yang dinilai berdasarkan % nilai maksimummembaik untuk semua aspek (seperti: kemampuan berbahasa, kemampuan memberikan alasan, penglihatan, konsentrasi, menghafal dan mengingat untuk anak di kabupaten Tangerang, demikian juga di Jakarta Barat dan Kota Tangerang kecuali untuk kemampuan memberikan alasan dan mengingat. Dari studi ini dievaluasi bahwa prevalensi gizi kurang tidak berubah (21.8% Jakarta Barat, 23.5% Kota Tangerang, 39.0% kabupaten Tangerang. Hasil temuan lainnya adalah pengetahuan anak untuk kesehatan dan gizi masih  belum  baik  dan  prevalensi  kecacingan  yang  masih  30%  di  kabupaten  Tangerang. Direkomendasikan  agar  partisipasi  institusi  terkait  perlu  dioptimalkan  untuk

  1. Status of the nation's local mass transportation: performance and conditions. Report to the congress, June 1988. Biennial report

    Energy Technology Data Exchange (ETDEWEB)

    1988-06-01

    This document is the third biennial Report of the Secretary of Transportation to the United States Congress on the current performance and condition of the Nation's public mass-transportation systems. It updates the information and recommendations of the previous report and should be of value to the Congress and the Department for developing policy and program requirements to administer the Federal mass-transportation assistance program.

  2. The influence of athletic status on maximal and rapid isometric torque characteristics and postural balance performance in Division I female soccer athletes and non-athlete controls.

    Science.gov (United States)

    Palmer, Ty B; Hawkey, Matt J; Thiele, Ryan M; Conchola, Eric C; Adams, Bailey M; Akehi, Kazuma; Smith, Doug B; Thompson, Brennan J

    2015-07-01

    The purpose of this study was to examine the effectiveness of maximal and rapid isometric torque characteristics of the hip extensor muscles and postural balance performance to discriminate between female collegiate soccer athletes and non-athlete controls. Ten athletes (mean ± SE: age = 19·20 ± 0·36 year; mass = 62·23 ± 3·12 kg; height = 162·43 ± 1·70 cm) and 10 non-athletes (age = 20·30 ± 0·40 year; mass = 69·64 ± 3·20 kg; height = 163·22 ± 2·10 cm) performed two isometric maximal voluntary contractions (MVCs) of the hip extensor muscles. Peak torque (PT) and absolute and relative rate of torque development (RTD) at early (0-50 ms) and late (100-200 ms) phases of muscle contraction were examined during each MVC. Postural balance was assessed using a commercially designed balance testing device, which provides a measurement of static stability based on sway index (SI). Results indicated that absolute and relative RTD at 0-50 ms (RTD50 and RTD50norm) were greater (P = 0·007 and 0·026), and postural SI was lower (P = 0·022) in the athletes compared with the non-athletes. However, no differences (P = 0·375-0·709) were observed for PT nor absolute and relative RTD at 100-200 ms (RTD100-200 and RTD100-200norm). Significant relationships were also observed between RTD50 and RTD50norm and SI (r = -0·559 and -0·521; P = 0·010 and 0·019). These findings suggest that early rapid torque characteristics of the hip extensor muscles and postural balance performance may be sensitive and effective measures for discriminating between college-aged athletes and non-athletes. Coaches and practitioners may use these findings as performance evaluation tools to help in identifying athletes with both superior early rapid torque and balance performance abilities, which may possibly be an indicator of overall athletic potential. © 2014 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John

  3. HIV-infected Children in Malawi Have Decreased Performance on the 6-minute Walk Test With Preserved Cardiac Mechanics Regardless of Antiretroviral Treatment Status.

    Science.gov (United States)

    Sims Sanyahumbi, Amy E; Hosseinipour, Mina C; Guffey, Danielle; Hoffman, Irving; Kazembe, Peter N; McCrary, Madeline; Minard, Charles G; van der Horst, Charles; Sable, Craig A

    2017-07-01

    The aims of this study were to 1) determine if cardiac disease can be detected in HIV-infected children by strain imaging and 2) to evaluate differences in exercise performance between HIV-infected children on antiretroviral therapy (ART) and HIV-infected children not yet on ART and in HIV-uninfected children by 6-minute walk tests (6MWTs). This cross-sectional study evaluated cardiac function by echocardiogram and exercise performance by 6MWT in HIV-infected and HIV-uninfected children 4-18 years of age in Lilongwe, Malawi. Analyses compared HIV uninfected, HIV infected not yet on ART, and HIV infected on ART. Comparisons used χ test, t test, analysis of variance and multiple linear regression. No differences were found in ejection fraction, shortening fraction or strain in 73 children not yet on ART, 149 on ART and 77 HIV-uninfected controls. As viral load increased, children had worse circumferential strain. In addition, children receiving ART had better circumferential strain than those not yet on ART. Increased CD4 percentage was associated with better longitudinal strain and farther 6MWT distance. As longitudinal strain worsened, the 6MWT distance decreased. HIV-infected children not yet on ART walked a mean of 25.8 m less than HIV-uninfected children, and HIV-infected children on ART walked 25.9 m less (P = 0.015 comparing 3 groups). HIV-uninfected children performed better on the 6MWT than HIV-infected children. Lower viral load, being on ART, and higher CD4 percentage were associated with better strain measures. Better longitudinal strain was associated with a farther 6MWT distance. Overall, ejection fraction, shortening fraction and strain measures between groups were similar, so cardiac strain did not detect cardiac dysfunction in this young population.

  4. Slow recovery of blood glucose in the insulin tolerance test during the prepartum transition period negatively impacts the nutritional status and reproductive performance postpartum of dairy cows.

    OpenAIRE

    Lee, Hsu-Hsun; Kida, Katsuya; Miura, Ryotaro; Inokuma, Hisashi; Miyamoto, Akio; Kawashima, Chiho; Haneda, Shingo; Miyake, Yoh-ichi; Matsui, Motozumi

    2012-01-01

    In peripartum dairy cows, insulin resistance (IR) increases to adjust the direction of energy to lactation after calving. To investigate the effect of prepartum IR on postpartum reproductive performance, the insulin tolerance test (ITT) was applied to 15 cows at 3 weeks (Pre21) and 10 days (Pre10) before the predicted calving date. Blood glucose area under the curve (AUCglu) within 120 min after administration of 0.05 IU/kg-BW insulin was calculated. The occurrence of first ovulation, days to...

  5. The CMS muon system status and upgrades for LHC run-2 and performance of muon reconstruction with 13 TeV data

    CERN Document Server

    Battilana, Carlo

    2016-01-01

    The CMS muon system has played a key role for many physics results obtained from the LHC Run-1 and Run-2 data. During the Long Shutdown (2013-2014), as well as during the last year-end technical stop (2015-2016), significant consolidation and upgrades have been carried out on the muon detectors and on the L1 muon trigger. The algorithms for muon reconstruction and identification have also been improved for both the High-Level Trigger and the offline reconstruction. Results of the performance of muon detectors, reconstruction and trigger, obtained using data collected at 13 TeV center-of-mass energy during the 2015 and 2016 LHC runs, will be presented. Comparison of simulation with experimental data will also be discussed where relevant. The system's state of the art performance will be shown, and the improvements foreseen to achieve excellent overall quality of muon reconstruction in CMS, in the conditions expected during the high-luminosity phase of Run-2, will be described.

  6. The management system of health information CAFAM IPS : a look at the current status and propose new actions to improve its performance

    Directory of Open Access Journals (Sweden)

    Javier Andrés Urrego Varela

    2015-11-01

    Full Text Available The information management is a very important factor to organize the processes taking place in a company and for complex systems function in a most harmonious way possible. This work intends to present the diagnosis was performed to determine the extent of the problem environment management system of information on the health sub CAFAM , describing internal and external factors that might influence the construction of a future SGIS . We conclude that there is much to do in terms of organizing a CAFAM IPS SGI in Health , but are also given the objective and subjective conditions for progress in the development of this system to contribute to the development of the company.

  7. Effects of dietary resistant starch content on metabolic status, milk composition, and microbial profiling in lactating sows and on offspring performance.

    Science.gov (United States)

    Yan, H; Lu, H; Almeida, V V; Ward, M G; Adeola, O; Nakatsu, C H; Ajuwon, K M

    2017-02-01

    In the present study, the effects of dietary resistant starch (RS) content on serum metabolite and hormone concentrations, milk composition, and faecal microbial profiling in lactating sows, as well as on offspring performance was investigated. Sixteen sows were randomly allotted at breeding to two treatments containing low- and high-RS contents from normal and high-amylose corn varieties, respectively, and each treatment had eight replicates (sows). Individual piglet body weight (BW) and litter size were recorded at birth and weaning. Milk samples were obtained on day 10 after farrowing for composition analysis. On day 2 before weaning, blood and faecal samples were collected to determine serum metabolite and hormone concentrations and faecal microbial populations, respectively. Litter size at birth and weaning were not influenced (p > 0.05) by the sow dietary treatments. Although feeding the RS-rich diet to sows reduced (p = 0.004) offspring birth BW, there was no difference in piglet BW at weaning (p > 0.05). High-RS diet increased (p content, and tended (p = 0.09) to increase milk fat content in lactating sows. Feeding the RS-rich diet to sows increased (p bacterial population diversity. These results indicate that high-RS diets induce fatty acid mobilization and a greater intestinal bacterial richness in lactating sows, as well as a greater nutrient density in maternal milk, without affecting offspring performance at weaning. Journal of Animal Physiology and Animal Nutrition © 2016 Blackwell Verlag GmbH.

  8. Diagnostic performance of a rapid in-clinic test for the detection of Canine Parvovirus under different storage conditions and vaccination status.

    Science.gov (United States)

    Kantere, Maria C; Athanasiou, Labrini V; Spyrou, Vassiliki; Kyriakis, Constantinos S; Kontos, Vassilios; Chatzopoulos, Dimitrios C; Tsokana, Constantina N; Billinis, Charalambos

    2015-04-01

    Canine parvovirus (CPV) is one of the most common causes of acute haemorrhagic enteritis in young dogs, while clinical diagnosis is often indecisive. The aim of our study was to evaluate the diagnostic accuracy of an in-clinic rapid test in the detection of CPV infection in dogs. To this end, we compared the Rapid Diagnostic Kit of Canine Parvovirus, Coronavirus and Rotavirus antigen (Quicking(®)) to PCR, which is considered as the most reliable diagnostic method. A total of 78 duplicated faecal samples were collected from diarrhoeic dogs. Vaccination history within a month prior to the onset of diarrhoea was reported for 12 of the sampled dogs. The rapid diagnostic test was performed in 23 of the faecal samples directly, while the rest were placed into a sterile cotton tipped swab suitable for collection and transportation of viruses (Sigma Σ-VCM(®)) and stored at -20 °C. The sensitivity of the Quicking rapid diagnostic test compared to PCR in the total number of samples, in samples from non-vaccinated dogs and in samples tested directly after collection were 22.22% (95% CI: 13.27-33.57%), 26.67% (95% CI: 16.08-39.66%) and 76.47% (95% CI: 50.10-93.04%) respectively, while the specificity of the test was 100% in any case. In conclusion, negative results do not exclude parvoenteritis from the differential diagnosis, especially in dogs with early vaccination history, but a positive result almost certainly indicates CPV infection. An improved sensitivity may be expected when the test is performed immediately. Copyright © 2015 Elsevier B.V. All rights reserved.

  9. Determination of serum 25-hydroxy cholecalciferol using high-performance liquid chromatography: a reliable tool for assessment of vitamin D status.

    Science.gov (United States)

    Neyestani, Tirang R; Gharavi, A'azam; Kalayi, Ali

    2007-09-01

    This study was undertaken to design and set up a rather simple, reliable, and less expensive high-performance liquid chromatography (HPLC)-based method to assay 25(OH)D as a diagnostic tool for vitamin D assessment. Serum proteins were precipitated using ethanol and, after 10 minutes incubation at room temperature, methanol:isopropanol. The extraction was performed using hexane followed by evaporation under nitrogen flow. The sediment was then reconstituted in methanol and passed through a polypropylene filter. To run the chromatographic analysis, 20 microL of the filtrate was injected to the column. Peaks of 25(OH)D2 and 25(OH)D3 were both detected using a UV detector set at 265 nm. With a flow rate of 1.2 mL/minute, peaks of D3 and D2 vitamers were detected around 9.5 and 10.7 minutes, respectively. The intra- and inter-assay variations were 8.1% and 12.6%, respectively, and the recovery percent was found to be 100 +/- 5%. To compare the procedure with conventional methods, 90 serum samples from subjects (48 females and 42 males) aged 40.5 +/- 13.9 yrs, were analyzed for 25(OH)D using HPLC, competitive protein-binding assay (CPBA), and radioimmunoassay (RIA). Generally, CPBA and RIA assays both showed over-estimation of serum 25(OH)D, compared to HPLC. Though all three methods correlated significantly with each other, with the strongest between HPLC and RIA (r = 0.87, p < 0.001), both RIA and CPBA were found unreliable in detection of some deficient samples.

  10. Large block test status report

    International Nuclear Information System (INIS)

    Wilder, D.G.; Lin, W.; Blair, S.C.

    1997-01-01

    This report is intended to serve as a status report, which essentially transmits the data that have been collected to date on the Large Block Test (LBT). The analyses of data will be performed during FY98, and then a complete report will be prepared. This status report includes introductory material that is not needed merely to transmit data but is available at this time and therefore included. As such, this status report will serve as the template for the future report, and the information is thus preserved

  11. Reducing mineral usage in feedlot diets for Nellore cattle: II. Impacts of calcium, phosphorus, copper, manganese, and zinc contents on intake, performance, and liver and bone status.

    Science.gov (United States)

    Prados, L F; Sathler, D F T; Silva, B C; Zanetti, D; Valadares Filho, S C; Alhadas, H M; Detmann, E; Santos, S A; Mariz, L D S; Chizzotti, M L

    2017-04-01

    Weaned Nellore bulls ( = 36; 274 ± 34 kg) were used in a randomized block design with a 2 × 2 factorial arrangement of treatments to evaluate intake, fecal excretion, and performance with different concentrations of minerals. Experimental diets were formulated with 2 concentrations of Ca and P (macromineral factor; diet supplying 100% of Ca and P according to BR-CORTE () [CaP+] or diet without limestone and dicalcium phosphate [CaP-]) and 2 concentrations of microminerals (micromineral factor; diet with supplementation of microminerals [Zn, Mn, and Cu; CuMnZn+] or diet without supplementation of microminerals [Zn, Mn, and Cu; CuMnZn-]). The factor CaP- was formulated without the addition of limestone and dicalcium phosphate, and the factor CuMnZn- was formulated without inorganic supplementation of microminerals (premix). The diets were isonitrogenous (13.3% CP). Intake was individually monitored every day. Indigestible NDF was used as an internal marker for digestibility estimates. The bulls were slaughtered (84 or 147 d on feed), and then carcass characteristics were measured and liver and rib samples were collected. Feed, feces, rib bones, and liver samples were analyzed for DM, ash, CP, ether extract (EE), Ca, P, Zn, Mn, and Cu. There were no significant interactions ( ≥ 0.06) between macro- and micromineral supplementation for any variables in the study. Calcium, P, and micromineral concentrations did not affect ( ≥ 0.20) intake of DM, OM, NDF, EE, CP, TDN, and nonfiber carbohydrates (NFC). Calcium and P intake were affected ( < 0.01) by macromineral factor. Animals fed without Ca and P supplementation consumed less of these minerals. Dry matter and nutrient fecal excretion (OM, NDF, EE, CP, and NFC) were similar ( ≥ 0.23) among all factors. Performance and carcass characteristics were similar ( ≥ 0.09) among diets. The content of ash in rib bones was not affected by diets ( ≥ 0.06). Plasma P and phosphatase alkaline concentrations were similar (

  12. Performance comparison of biotic indices measuring the ecological status base on soft-bottom macroinvertebrates: a study along the shallow Gomishan lagoon (Southeast Caspian Sea

    Directory of Open Access Journals (Sweden)

    Nabee Basatnia

    2015-12-01

    Full Text Available Abstract This paper aims to test the suitability of some biotic indices for their application in Southeast Caspian Sea. For this purpose, the ecological quality of the Gomishan lagoon was assessed using three biotic indices (AMBI, BENTIX, BOPA during summer and autumn 2010. The results from the application of the biotic indices do not highlight a clear distinction between the stations. The results show that two of the indices (AMBI and BENTIX are very close in terms of diagnosis (good and high and seem to generally perform better than BOPA. In addition, Principal Component Analysis (PCA based on abiotic parameters showed clear spatial and temporal differences in environmental variables. However, at this shallow sites with low human pressure and high water residence times, such benthic community composition can be associated with physical stress due to salinity increase and to changes in environmental characteristics, triggered by conventional seasonal variations. Natural variability of transitional waters is a crucial factor for a correct evaluation of the ecological condition of macroinvertebrate communities across the lagoonal system.

  13. X-ray structural study of Ge(001):Te 1x1 performed at the advanced photon source. Current status of the surface-interface structure beamline at SPring-8

    CERN Document Server

    Sakata, O

    2002-01-01

    This article is composed of two parts. In the first half, we describe a study that we performed at 5ID-C of the Dupont- Northwestern University-Dow (DND) CAT in the Advanced Photon Source, the Argonne National Laboratory for 1998 to 2000. A surface structure of Ge(001):Te 1x1 was determined by least-squares fits of x-ray scattered intensities with calculations based on some surface atomic structural models. The fitted structural model has a characteristic that a direction of a Ge-Ge dimer bond on the first Ge atomic layer is perpendicular to a Te missing row. It was distinct from those based on first-principles total energy calculations. In the second half, we introduce up-to-the-minute status of BL13XU for surface-interface structural studies at SPring-8. Scientific research goals we desire are mentioned as well. (author)

  14. Palliative effects of extra virgin olive oil, gallic acid, and lemongrass oil dietary supplementation on growth performance, digestibility, carcass traits, and antioxidant status of heat-stressed growing New Zealand White rabbits.

    Science.gov (United States)

    Al-Sagheer, Adham A; Daader, Ahmed H; Gabr, Hassan A; Abd El-Moniem, Elham A

    2017-03-01

    This study explored the effects of supplemental dietary extra virgin olive oil (EVOO), gallic acid (GA), or lemongrass essential oil (LGEO) on growth performance, nutrient digestibility, carcass traits, lipid peroxidation, hematological, and antioxidative status in growing rabbits under heat stress conditions. A total of 48 male growing New Zealand White rabbits were randomly divided into four equal groups, which received a basal diet without any supplementation or supplemented with 15 g EVOO, 500 mg GA, or 400 mg LGEO/kg of diet, for eight consecutive weeks. Results revealed that the overall mean of temperature humidity index was 84.67 ± 0.35, reflecting a state of severe heat stress. Moreover, dietary supplementation with EVOO, GA, or LGEO significantly increased live body weight and daily body weight gain but decreased both feed conversion ratio and daily water consumption. Additionally, a significant increase in both organic matter and crude protein digestibility besides a remarkable elevation in the nutritive values of digestible crude protein, total digestible nutrients, and digestible energy, as well as an increase in the numbers of WBCs, lymphocytes, and heterophils was significant in EVOO-supplemented rabbits. Supplementation with EVOO, GA, or LGEO in the heat-stressed growing rabbit's diet enhanced catalase activity and reduced glutathione content, whereas EVOO-treated rabbits had the highest values. Also, malondialdehyde activity was reduced in response to all tested additives. In conclusion, these findings suggested that addition of EVOO, GA, or LGEO in growing rabbit's diet could be used effectively to alleviate negative impacts of heat stress load on performance, nutrient digestibility, oxidative status, and hemato-biochemical features. Furthermore, among these additives, EVOO achieved the best effects.

  15. Effects of prior testing lasting a full year in NCANDA adolescents: Contributions from age, sex, socioeconomic status, ethnicity, site, family history of alcohol or drug abuse, and baseline performance

    Directory of Open Access Journals (Sweden)

    Edith V. Sullivan

    2017-04-01

    Full Text Available Longitudinal study provides a robust method for tracking developmental trajectories. Yet inherent problems of retesting pose challenges in distinguishing biological developmental change from prior testing experience. We examined factors potentially influencing change scores on 16 neuropsychological test composites over 1 year in 568 adolescents in the National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA project. The twice-minus-once-tested method revealed that performance gain was mainly attributable to testing experience (practice with little contribution from predicted developmental effects. Group mean practice slopes for 13 composites indicated that 60% to ∼100% variance was attributable to test experience; General Ability accuracy showed the least practice effect (29%. Lower baseline performance, especially in younger participants, was a strong predictor of greater gain. Contributions from age, sex, ethnicity, examination site, socioeconomic status, or family history of alcohol/substance abuse were nil to small, even where statistically significant. Recognizing that a substantial proportion of change in longitudinal testing, even over 1-year, is attributable to testing experience indicates caution against assuming that performance gain observed during periods of maturation necessarily reflects development. Estimates of testing experience, a form of learning, may be a relevant metric for detecting interim influences, such as alcohol use or traumatic episodes, on behavior.

  16. Status of safeguards instrumentation

    International Nuclear Information System (INIS)

    Higinbotham, W.A.

    The International Atomic Energy Agency is performing safeguards at some nuclear power reactors, 50 bulk processing facilities, and 170 research facilities. Its verification activities require the use of instruments to measure nuclear materials and of surveillance instruments to maintain continuity of knowledge of the locations of nuclear materials. Instruments that are in use and under development to measure weight, volume, concentration, and isotopic composition of nuclear materials, and the major surveillance instruments, are described in connection with their uses at representative nuclear facilities. The current status of safeguards instrumentation and the needs for future development are discussed

  17. The status of GALLEX

    Energy Technology Data Exchange (ETDEWEB)

    Kirsten, T.; Anselmann, P.; Breitenbach, M.; Hampel, W.; Heusser, G.; Kiko, J.; Kirsten, T.; Lenzing, A.; Pernicka, E.; Plaga, R.; Povh, B.; Schlosser, C.; Voelk, H.; Wink, R.; Wojcik, M. (Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany, F.R.)); Bellotti, E. (Laboratori Nazionali del Gran Sasso (Italy)); Ammon, R. v.; Balata, M.; Ebert, K.; Fritsch, T.; Hellriegel, K.; Henrich, E.; Stieglitz, L.; Weyrich, F. (Kernforschungszentrum Karlsruhe GmbH (Germany, F.R.)); Cremonesi, O.; Fiorini, E.; Ragazzi, S.; Zanotti, L. (Milan Univ. (Italy). Dipt. di Fisica); Feilitzsch, F. v.; Moessbauer, R.; Schanda, U. (Technische Univ. Muenchen, Garching (Germany, F.R.). Fakultaet fuer Physik); Berthomieu, G.; Schatzmann, E. (Nice Univ., 06 (France). Observatoire); Carmi, I.; Dostrovsky, I. (Weizmann Inst. of Science, Rehovoth (Israel)); D' Angelo, S.; Bacci, C.; Belli, P.; Bernabei, R.; Paoluzi, L. (Rome-2 Univ. (Italy)); Cribier, M.; Dupont, G.; Gosset, L.; Pichard, B.; Rich, J.; Spiro; GALLEX Collaboration

    1991-04-01

    A radiochemical Gallium-Solar-Neutrino Detector has been set up at the Gran Sasso Underground Laboratory. All major installations are implemented and the target, 53,5 m{sup 3} of galliumchloride solution containing 30.3 tons of gallium, has been brought underground after removing cosmogenic Ge-isotopes through nitrogen purge. This final implementation status and the achieved parameters characterizing the experiment are described in this report. Full scale performance tests and optimalization of the operating conditions of the extraction system are presently under way. (orig.).

  18. Integrated process status overview

    International Nuclear Information System (INIS)

    Gertman, D.I.; Gaudio, P. Jr.

    1986-01-01

    This report summarizes findings to date with the IPSO, a large plant status overview currently under development at the OECD Halden Reactor Project. As part of a joint Halden and Combustion Engineering project, the overview is being tested in part to determine whether the large screen overview concept being entertained for use in the nuclear power plant (NPP) industry will facilitate operator performance. To this end an interactive simulation technique was used to establish a proof-of-principle test for the IPSO. Process control, operations, and human factors experts at Halden participated in the test and evaluation

  19. NESTOR: A status report

    CERN Document Server

    Anassontzis, E G; Barone, M; Foudas, C; Grammatikakis, G; Katsanevas, S; Kourkoumelis, C; Manousakis-Katsikakis, A; Resvanis, L K; Siotis, I; Sotiriou, S A; Voulgaris, G; Minkowski, P; Grieder, P K F; Ball, A E; Bottai, S; Cartacci, A M; Monteleoni, B; Naumov, Vadim A; Trasatti, L; Fahrun, E; Keusen, U; Koske, P; Rathlev, J; Schmidt, N P; Voight, G; Bezrukov, Leonid B; Butkevich, A V; Dedenko, L G; Karaevsky, S K; Mironovich, A A; Zakharov, L M; Zheleznykh, I M; Zhukov, V A; Demidova, T A; Deineko, A O; Eremeev, A P; Paka, V T; Permyakov, A A; Platonov, M N; Rukol, V Kh; Sheremet, N A; Surin, N M; Albul, V I; Ledenev, V V

    2000-01-01

    NESTOR is an underwater neutrino astrophysics laboratory to be located in the international waters of the southwest of Greece. The first phase of this experiment is the construction and deployment of one hexagonal tower consisting of 168 optical modules, with effective are of 20000m2 for E ⩾ TeV neutrinos. Over the past few years detailed studies of the site have been carried out while many tests have been performed. The current status of the preparation of the experiment and the future plans will be presented.

  20. A Comparison of Natural (D-α-tocopherol) and Synthetic (DL-α-tocopherol Acetate) Vitamin E Supplementation on the Growth Performance, Meat Quality and Oxidative Status of Broilers.

    Science.gov (United States)

    Cheng, K; Niu, Y; Zheng, X C; Zhang, H; Chen, Y P; Zhang, M; Huang, X X; Zhang, L L; Zhou, Y M; Wang, T

    2016-05-01

    The present study was conducted to compare the supplementation of natural (D-α-tocopherol) and synthetic (DL-α-tocopherol acetate) vitamin E on the growth performance, meat quality, muscular antioxidant capacity and genes expression related to oxidative status of broilers. A total of 144 1 day-old Arbor Acres broiler chicks were randomly allocated into 3 groups with 6 replicates of 8 birds each. Birds were given a basal diet (control group), and basal diet supplemented with either 20 IU D-α-tocopherol or DL-α-tocopherol acetate for 42 days, respectively. The results indicated that treatments did not alter growth performance of broilers (p>0.05). Compared with the control group, concentration of α-tocopherol in the breast muscle was increased by the supplementation of vitamin E (pnatural vitamin E group (pnatural vitamin E group (pnatural rather than synthetic vitamin E reduced MDA accumulation in the thigh (pnatural nor synthetic vitamin E supplementation altered muscular mRNA abundance of genes related to oxidative stress (p>0.05). It was concluded that vitamin E supplementation, especially the natural vitamin E, can enhance the retention of muscular α-tocopherol, improve meat quality and muscular antioxidant capacity of broilers.

  1. A Comparison of Natural (D-α-tocopherol and Synthetic (DL-α-tocopherol Acetate Vitamin E Supplementation on the Growth Performance, Meat Quality and Oxidative Status of Broilers

    Directory of Open Access Journals (Sweden)

    K. Cheng

    2016-05-01

    Full Text Available The present study was conducted to compare the supplementation of natural (D-α-tocopherol and synthetic (DL-α-tocopherol acetate vitamin E on the growth performance, meat quality, muscular antioxidant capacity and genes expression related to oxidative status of broilers. A total of 144 1 day-old Arbor Acres broiler chicks were randomly allocated into 3 groups with 6 replicates of 8 birds each. Birds were given a basal diet (control group, and basal diet supplemented with either 20 IU D-α-tocopherol or DL-α-tocopherol acetate for 42 days, respectively. The results indicated that treatments did not alter growth performance of broilers (p>0.05. Compared with the control group, concentration of α-tocopherol in the breast muscle was increased by the supplementation of vitamin E (p0.05. It was concluded that vitamin E supplementation, especially the natural vitamin E, can enhance the retention of muscular α-tocopherol, improve meat quality and muscular antioxidant capacity of broilers.

  2. The combined status of physical performance and depressive symptoms is strongly associated with a history of falling in community-dwelling elderly: cross-sectional findings from the Obu Study of Health Promotion for the Elderly (OSHPE).

    Science.gov (United States)

    Makizako, Hyuma; Shimada, Hiroyuki; Doi, Takehiko; Yoshida, Daisuke; Tsutsumimoto, Kota; Uemura, Kazuki; Anan, Yuya; Park, Hyuntae; Lee, Sangyoon; Ito, Tadashi; Suzuki, Takao

    2014-01-01

    The purpose of this study was to examine whether the combined factors of physical performance, depressive symptoms and cognitive status are significantly associated with a history of falling in community-dwelling elderly. We performed a cross-sectional community-based survey, the OSHPE, from August 2011 to February 2012. In total, 5104 community-dwelling older adults aged 65 years and older (mean age 72.0) participated in the OSHPE. Participants underwent a grip strength (GS) test, chair stand test (CST), Timed Up & Go (TUG) test, Geriatric Depression Scale (GDS), and Mini-Mental State Examination (MMSE). Of the 4481 participants who met our requirements, 645 (14.4%) participants reported falling at least once in the past year. In a signal detection analysis (SDA), we found that the combination of GDS (≥6 points) and TUG (≥10.6 s) had the highest fall rate (36.4%), and the combination of GDS (fall rate (11.7%). The highest fall rate group had a significantly higher odds ratio (OR) compared with the lowest fall rate group after adjusting for other potentially confounding variables [OR 3.12 (95% confidence interval (CI) 2.08-4.68) phistory of falling in community-dwelling elderly. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  3. Status Report on PEP-II Performance

    International Nuclear Information System (INIS)

    Matter, Regina S.

    2002-01-01

    PEP-II [1-9] is an e+e- collider with asymmetric energies (3.1 and 9 GeV, respectively) in a 2200 m tunnel at the Stanford Linear Accelerator Center. The collider produces B mesons to study a particle physics effect called CP violation as well as other physics topics. PEP-II was completed in 1998 with the first luminosity generated in July of that year. The installation of the BaBar Detector was finished in May 1999. The overall layout of PEP-II is shown in Figure 1 and the interaction region of PEP-II in Figure 2. The accelerator parameters and achievements of the High Energy Ring (HER) are listed in Table 1 and those for the Low Energy Ring (LER) in Table 2. The two beams collide at a single point in the IR2 hall where the BaBar detector is located. Beam parameters at the best luminosity are shown in Table 3 and PEP-II milestones in Table 4. In August 1999 PEP-II passed the world's record for luminosity which was 8.1x10 32 /cm 2 /s. The present luminosity in PEP-II is 2.15x10 33 /cm 2 /s which is 72% of the design. In June 2000 PEP-II delivered an integrated luminosity of 150 pb -1 in one day, which is above the design integrated luminosity per day of 135 pb -1 . Over the past year PEP-II has delivered over 12 fb -1 to BaBar. BaBar has logged over 11 pb -1 . The present plan is collide until the end of October 2000 followed by a three month installation period

  4. Model Validation Status Review

    International Nuclear Information System (INIS)

    E.L. Hardin

    2001-01-01

    The primary objective for the Model Validation Status Review was to perform a one-time evaluation of model validation associated with the analysis/model reports (AMRs) containing model input to total-system performance assessment (TSPA) for the Yucca Mountain site recommendation (SR). This review was performed in response to Corrective Action Request BSC-01-C-01 (Clark 2001, Krisha 2001) pursuant to Quality Assurance review findings of an adverse trend in model validation deficiency. The review findings in this report provide the following information which defines the extent of model validation deficiency and the corrective action needed: (1) AMRs that contain or support models are identified, and conversely, for each model the supporting documentation is identified. (2) The use for each model is determined based on whether the output is used directly for TSPA-SR, or for screening (exclusion) of features, events, and processes (FEPs), and the nature of the model output. (3) Two approaches are used to evaluate the extent to which the validation for each model is compliant with AP-3.10Q (Analyses and Models). The approaches differ in regard to whether model validation is achieved within individual AMRs as originally intended, or whether model validation could be readily achieved by incorporating information from other sources. (4) Recommendations are presented for changes to the AMRs, and additional model development activities or data collection, that will remedy model validation review findings, in support of licensing activities. The Model Validation Status Review emphasized those AMRs that support TSPA-SR (CRWMS M and O 2000bl and 2000bm). A series of workshops and teleconferences was held to discuss and integrate the review findings. The review encompassed 125 AMRs (Table 1) plus certain other supporting documents and data needed to assess model validity. The AMRs were grouped in 21 model areas representing the modeling of processes affecting the natural and

  5. Model Validation Status Review

    Energy Technology Data Exchange (ETDEWEB)

    E.L. Hardin

    2001-11-28

    The primary objective for the Model Validation Status Review was to perform a one-time evaluation of model validation associated with the analysis/model reports (AMRs) containing model input to total-system performance assessment (TSPA) for the Yucca Mountain site recommendation (SR). This review was performed in response to Corrective Action Request BSC-01-C-01 (Clark 2001, Krisha 2001) pursuant to Quality Assurance review findings of an adverse trend in model validation deficiency. The review findings in this report provide the following information which defines the extent of model validation deficiency and the corrective action needed: (1) AMRs that contain or support models are identified, and conversely, for each model the supporting documentation is identified. (2) The use for each model is determined based on whether the output is used directly for TSPA-SR, or for screening (exclusion) of features, events, and processes (FEPs), and the nature of the model output. (3) Two approaches are used to evaluate the extent to which the validation for each model is compliant with AP-3.10Q (Analyses and Models). The approaches differ in regard to whether model validation is achieved within individual AMRs as originally intended, or whether model validation could be readily achieved by incorporating information from other sources. (4) Recommendations are presented for changes to the AMRs, and additional model development activities or data collection, that will remedy model validation review findings, in support of licensing activities. The Model Validation Status Review emphasized those AMRs that support TSPA-SR (CRWMS M&O 2000bl and 2000bm). A series of workshops and teleconferences was held to discuss and integrate the review findings. The review encompassed 125 AMRs (Table 1) plus certain other supporting documents and data needed to assess model validity. The AMRs were grouped in 21 model areas representing the modeling of processes affecting the natural and

  6. Cumulative Intracranial Tumor Volume Augments the Prognostic Value of Diagnosis-Specific Graded Prognostic Assessment Model for Survival in Patients with Melanoma Cerebral Metastases

    DEFF Research Database (Denmark)

    Hirshman, Brian R; Wilson, Bayard R; Ali, Mir Amaan

    2018-01-01

    BACKGROUND: The diagnosis-specific graded prognostic assessment scale (ds-GPA) for patients with melanoma brain metastasis (BM) utilizes only 2 key prognostic variables: Karnofsky performance status and the number of intracranial metastases. We wished to determine whether inclusion of cumulative ...

  7. A 12-week interdisciplinary rehabilitation trial in patients with gliomas

    DEFF Research Database (Denmark)

    Hansen, Anders; Søgaard, Karen; Minet, Lisbeth Rosenbek

    2018-01-01

    rehabilitation intervention of physical therapy and occupational therapy in the initial treatment phase of patients with gliomas whose Karnofsky performance status is ≥70 is safe and feasible, if relevant inclusion criteria and precautionary screening are made. With the revised protocol, we are confident...

  8. Status Configurations, Military Service and Higher Education.

    Science.gov (United States)

    Wang, Lin; Elder, Glen H; Spence, Naomi J

    2012-12-01

    The U.S. Armed Forces offer educational and training benefits as incentives for service. This study investigates the influence of status configurations on military enlistment and their link to greater educational opportunity. Three statuses (socioeconomic status of origin, cognitive ability and academic performance) have particular relevance for life course options. We hypothesize that young men with inconsistent statuses are more likely to enlist than men with consistent status profiles, and that military service improves access to college for certain configurations. Analyses of the National Longitudinal Study of Adolescent Health (Add Health) show (1. that several status configurations markedly increased the likelihood of military enlistment and (2. within status configurations, recruits were generally more likely to enroll in higher education than nonveterans, with associate degrees being more likely.

  9. Status Configurations, Military Service and Higher Education

    Science.gov (United States)

    Wang, Lin; Elder, Glen H.; Spence, Naomi J.

    2012-01-01

    The U.S. Armed Forces offer educational and training benefits as incentives for service. This study investigates the influence of status configurations on military enlistment and their link to greater educational opportunity. Three statuses (socioeconomic status of origin, cognitive ability and academic performance) have particular relevance for life course options. We hypothesize that young men with inconsistent statuses are more likely to enlist than men with consistent status profiles, and that military service improves access to college for certain configurations. Analyses of the National Longitudinal Study of Adolescent Health (Add Health) show (1. that several status configurations markedly increased the likelihood of military enlistment and (2. within status configurations, recruits were generally more likely to enroll in higher education than nonveterans, with associate degrees being more likely. PMID:24511161

  10. Predicting outcome of status epilepticus.

    Science.gov (United States)

    Leitinger, M; Kalss, G; Rohracher, A; Pilz, G; Novak, H; Höfler, J; Deak, I; Kuchukhidze, G; Dobesberger, J; Wakonig, A; Trinka, E

    2015-08-01

    Status epilepticus (SE) is a frequent neurological emergency complicated by high mortality and often poor functional outcome in survivors. The aim of this study was to review available clinical scores to predict outcome. Literature review. PubMed Search terms were "score", "outcome", and "status epilepticus" (April 9th 2015). Publications with abstracts available in English, no other language restrictions, or any restrictions concerning investigated patients were included. Two scores were identified: "Status Epilepticus Severity Score--STESS" and "Epidemiology based Mortality score in SE--EMSE". A comprehensive comparison of test parameters concerning performance, options, and limitations was performed. Epidemiology based Mortality score in SE allows detailed individualization of risk factors and is significantly superior to STESS in a retrospective explorative study. In particular, EMSE is very good at detection of good and bad outcome, whereas STESS detecting bad outcome is limited by a ceiling effect and uncertainty of correct cutoff value. Epidemiology based Mortality score in SE can be adapted to different regions in the world and to advances in medicine, as new data emerge. In addition, we designed a reporting standard for status epilepticus to enhance acquisition and communication of outcome relevant data. A data acquisition sheet used from patient admission in emergency room, from the EEG lab to intensive care unit, is provided for optimized data collection. Status Epilepticus Severity Score is easy to perform and predicts bad outcome, but has a low predictive value for good outcomes. Epidemiology based Mortality score in SE is superior to STESS in predicting good or bad outcome but needs marginally more time to perform. Epidemiology based Mortality score in SE may prove very useful for risk stratification in interventional studies and is recommended for individual outcome prediction. Prospective validation in different cohorts is needed for EMSE, whereas

  11. Emergency Surgery for Refractory Status Epilepticus.

    Science.gov (United States)

    Botre, Abhijeet; Udani, Vrajesh; Desai, Neelu; Jagadish, Spoorthy; Sankhe, Milind

    2017-08-15

    Management of refractory status epilepticus in children is extremely challenging. Two children with medically refractory status epilepticus, both of whom had lesional pathology on MRI and concordant data on EEG and PET scan. Emergency hemispherotomy performed in both patients. A complete, sustained seizure freedom obtained postoperatively. Emergency surgery is a treatment option in selected cases of drug refractory status epilepticus with lesional pathology and concordant data.

  12. Less Common Etiologies of Status Epilepticus

    Science.gov (United States)

    Bleck, Thomas P

    2010-01-01

    Status epilepticus is treated as a neurologic emergency and only later are the potential etiologies assessed. While sometimes the cause for status epilepticus is apparent (e.g., antiepileptic drug withdrawal), all too often it is not identified, even after extensive diagnostic testing has been performed. With emphasis on the less-common etiologies, this review will cover various probable and known causes of status epilepticus among adults, children, and those patients with refractory epilepsy. PMID:20231917

  13. The Medicina Station Status Report

    Science.gov (United States)

    Orfei, Alessandro; Orlati, Andrea; Maccaferri, Giuseppe

    2013-01-01

    General information about the Medicina Radio Astronomy Station, the 32-m antenna status, and the staff in charge of the VLBI observations is provided. In 2012, the data from geodetic VLBI observations were acquired using the Mark 5A recording system with good results. Updates of the hardware were performed and are briefly described.

  14. Status of the OPERA Experiment

    CERN Document Server

    Zimmermann, R.

    2006-01-01

    In this article the physics motivation and the detector design of the OPERA experiment will be reviewed. The construction status of the detector, which will be situated in the CNGS beam from CERN to the Gran Sasso laboratory, will be reported. A survey on the physics performance will be given and the physics plan in 2006 will be presented.

  15. Current Status and Future Directions of Targeted Peptide Radionuclide Therapy

    International Nuclear Information System (INIS)

    Valkema, R.

    2009-01-01

    Current status: Peptide receptor radionuclide therapy (PRRT) is currently almost exclusively targeted at the somatostatin receptor (sst). Of the 5 receptor subtypes, sst2 is frequently very highly expressed at the cell surface of neuroendocrine tumors (NET). Octreotide is a small and stable derivative of native somatostatin, which can be very well labeled with therapeutic radionuclides such as the beta-emitters ''9''0Y, ''1''7''7Lu or the Auger emitter ''1''1''1In, chelated in DTPA or DOTA, linked to the peptide. All current therapeutic octreotide derivatives are agonists that are internalized in the cell. The affinity for the sst2 receptor is better for [DOTA,Tyr''3]octreotate than for [DOTA,Tyr''3]octreotide or [DTPA]octreotide. ''9''0Y is a pure beta-emitter, with a half-life of 2.7 days, a high energy of 2.270 MeV, and a maximum penetration in tissue of 12mm. ''1''7''7Lu with a half-life of 6.7 days emits a low abundance of gamma photons as well as beta particles of 497 keV, with a maximum tissue penetration of 2 mm. ''1''7''7Lu-[DOTA,Tyr''3]octreotate (Lu-DOTATE), ''9''0Y-[DOTA,Tyr''3]octreotate (Y-DOTATATE) and ''9''0Y-[DOTA,Tyr''3]octreotide (Y-DOTATOC) are today the most frequently used therapeutic radiopeptides. Main inclusion criteria: inoperable and/or metastatic NET, receptor-positivity in all known lesions demonstrated by sufficient uptake on ''1''1''1In-octreotide scintigraphy (intensity > liver parenchyma), life expectancy at least 3-6 months, sufficient bone marrow reserve (hemoglobin (HGB) ≥ 5 mmol/L, white blood cells (WBC) ≥ 2*10 9 /L, platelets (PLT) ≥ 75*10 12 /L), sufficient renal function (serum creatinine 40 mL/min), sufficient hepatic and cardiac reserve. Karnofski score ≥50. Efficacy: several groups have reported objective response rates (RECIST or WHO/SWOG; CT or MRI based). Complete remission (CR) is rarely seen, partial remission (PR; >50% shrinkage SWOG) in 7% - 37%, minor remission (MR, 25% - 50% shrinkage) in 13% - 17

  16. Evaluation of PWR and BWR assembly benchmark calculations. Status report of EPRI computational benchmark results, performed in the framework of the Netherlands` PINK programme (Joint project of ECN, IRI, KEMA and GKN)

    Energy Technology Data Exchange (ETDEWEB)

    Gruppelaar, H. [Netherlands Energy Research Foundation (ECN), Petten (Netherlands); Klippel, H.T. [Netherlands Energy Research Foundation (ECN), Petten (Netherlands); Kloosterman, J.L. [Netherlands Energy Research Foundation (ECN), Petten (Netherlands); Hoogenboom, J.E. [Technische Univ. Delft (Netherlands). Interfacultair Reactor Instituut; Leege, P.F.A. de [Technische Univ. Delft (Netherlands). Interfacultair Reactor Instituut; Verhagen, F.C.M. [Keuring van Electrotechnische Materialen NV, Arnhem (Netherlands); Bruggink, J.C. [Gemeenschappelijke Kernenergiecentrale Nederland N.V., Dodewaard (Netherlands)

    1993-11-01

    Benchmark results of the Dutch PINK working group on calculational benchmarks on single pin cell and multipin assemblies as defined by EPRI are presented and evaluated. First a short update of methods used by the various institutes involved is given as well as an update of the status with respect to previous performed pin-cell calculations. Problems detected in previous pin-cell calculations are inspected more closely. Detailed discussion of results of multipin assembly calculations is given. The assembly consists of 9 pins in a multicell square lattice in which the central pin is filled differently, i.e. a Gd pin for the BWR assembly and a control rod/guide tube for the PWR assembly. The results for pin cells showed a rather good overall agreement between the four participants although BWR pins with high void fraction turned out to be difficult to calculate. With respect to burnup calculations good overall agreement for the reactivity swing was obtained, provided that a fine time grid is used. (orig.)

  17. Evaluation of PWR and BWR assembly benchmark calculations. Status report of EPRI computational benchmark results, performed in the framework of the Netherlands' PINK programme (Joint project of ECN, IRI, KEMA and GKN)

    International Nuclear Information System (INIS)

    Gruppelaar, H.; Klippel, H.T.; Kloosterman, J.L.; Hoogenboom, J.E.; Bruggink, J.C.

    1993-11-01

    Benchmark results of the Dutch PINK working group on calculational benchmarks on single pin cell and multipin assemblies as defined by EPRI are presented and evaluated. First a short update of methods used by the various institutes involved is given as well as an update of the status with respect to previous performed pin-cell calculations. Problems detected in previous pin-cell calculations are inspected more closely. Detailed discussion of results of multipin assembly calculations is given. The assembly consists of 9 pins in a multicell square lattice in which the central pin is filled differently, i.e. a Gd pin for the BWR assembly and a control rod/guide tube for the PWR assembly. The results for pin cells showed a rather good overall agreement between the four participants although BWR pins with high void fraction turned out to be difficult to calculate. With respect to burnup calculations good overall agreement for the reactivity swing was obtained, provided that a fine time grid is used. (orig.)

  18. Energy status and ovarian follicular development

    NARCIS (Netherlands)

    Meng, Li

    2016-01-01

    Female reproduction is tightly linked to body energy status and it has become increasingly clear that disturbed energy metabolism can negatively affect reproductive performance. Nevertheless, the way how a disturbed energy status affects ovarian follicular reserve as well as follicular

  19. Status report on the ADVANCED LIGHT SOURCE control system

    International Nuclear Information System (INIS)

    Magyary, S.; Chin, M.; Fahmie, M.; Lancaster, H.; Molinari, P.; Robb, A.; Timossi, C.; Young, J.

    1992-01-01

    This paper is a status report on the ADVANCED LIGHT SOURCE (ALS) control system. The current status, performance data, and future plans will be discussed. Manpower, scheduling, and costs issues are addressed. (author)

  20. Diet-induced changes in iron and n-3 fatty acid status and associations with cognitive performance in 8-11-year-old Danish children: secondary analyses of the Optimal Well-Being, Development and Health for Danish Children through a Healthy New Nordic Diet School Meal Study.

    Science.gov (United States)

    Sørensen, Louise Bergmann; Damsgaard, Camilla Trab; Dalskov, Stine-Mathilde; Petersen, Rikke Agnete; Egelund, Niels; Dyssegaard, Camilla Brørup; Stark, Ken D; Andersen, Rikke; Tetens, Inge; Astrup, Arne; Michaelsen, Kim Fleisher; Lauritzen, Lotte

    2015-11-28

    Fe and n-3 long-chain PUFA (n-3 LCPUFA) have both been associated with cognition, but evidence remains inconclusive in well-nourished school-aged children. In the Optimal Well-Being, Development and Health for Danish Children through a Healthy New Nordic Diet (OPUS) School Meal Study, the 3-month intervention increased reading performance, inattention, impulsivity and dietary intake of fish and Fe. This study investigated whether the intervention influenced n-3 LCPUFA and Fe status and, if so, explored how these changes correlated with the changes in cognitive performance. The study was a cluster-randomised cross-over trial comparing school meals with packed lunch (control). At baseline and after each treatment, we measured serum ferritin, whole-blood n-3 LCPUFA and Hb, and performance in reading, mathematics and d2-test of attention. Data were analysed using mixed models (n 726) and principal component analysis of test performances (n 644), which showed two main patterns: 'school performance' and 'reading comprehension'. The latter indicated that children with good reading comprehension were also more inattentive and impulsive (i.e. higher d2-test error%). The intervention improved 'school performance' (P=0·015), 'reading comprehension' (P=0·043) and EPA+DHA status 0·21 (95% CI 0·15, 0·27) w/w % (Pschool performance' in girls, but with better 'reading comprehension' in both boys and girls. Both baseline EPA+DHA status and the intervention-induced increase in EPA+DHA status was positively associated with 'school performance', suggesting that n-3 LCPUFA could potentially explain approximately 20 % of the intervention effect. These exploratory associations indicate that increased fish intake might explain some of the increase in reading performance and inattention in the study.

  1. LARGE BLOCK TEST STATUS REPORT

    International Nuclear Information System (INIS)

    D.G. WILDER, W. LIN, S.C. BLAIR, T. BUSCHECK, R.C. CARLSON, K. LEE, A. MEIKE, A.L. RAMIREZ, J.L. WAGONER, AND J. WANG

    1997-01-01

    This report is intended to serve as a status report, which essentially transmits the data that have been collected to date on the Large Block Test (LBT). The analyses of data will be performed during FY98, and then a complete report will be prepared. This status report includes introductory material that is not needed merely to transmit data but is available at this time and therefore included. As such, this status report will serve as the template for the future report, and the information is thus preserved. The United States Department of Energy (DOE) is investigatinq the suitability of Yucca Mountain (YM) as a potential site for the nation's first high-level nuclear waste repository. As shown in Fig. 1-1, the site is located about 120 km northwest of Las Vegas, Nevada, in an area of uninhabited desert

  2. Innovations, status, and networks

    NARCIS (Netherlands)

    P. Wang (Pengfei)

    2016-01-01

    markdownabstractTo obtain and maintain competitive advantage, firms need to implement appropriate innovation strategies (i.e. exploration or exploitation) and acquire status in external networks. In this dissertation, I investigate how innovation strategy, status, and network structure jointly

  3. USCIS My Case Status

    Data.gov (United States)

    Department of Homeland Security — USCIS provide a way for the public who applied for U.S. citizenship to check the status of their application online. To view the status of a case, the application...

  4. Health Status of Current National Guard Members

    National Research Council Canada - National Science Library

    Proctor, Susan P

    2005-01-01

    .... The objectives are to: 1) describe the current health status of this ARNG cohort, 2) examine to what extent the job strain of ARNG service affects the relationship between Civilian job strain and health and job performance outcomes and, 3...

  5. The Status of User Software on QCDOC

    International Nuclear Information System (INIS)

    Boyle, P.A.; Chen, D.; Christ, N.H.; Clark, M.; Cohen, S.D.; Cristian, C.; Dong, Z.; Gara, A.; Joo, B.; Jung, C.; Kim, C.; Levkova, L.; Liao, X.; Li, S.; Lin, H.; Liu, G.; Mawhinney, R.D.; Ohta, S.; Petrov, K.; Wettig, T.; Yamaguchi, A.

    2005-01-01

    The current status of QCDOC application software and the user environment are summarized. The performance of optimized routines for the Asqtad Hybrid Monte Carlo is discussed. Also, an update on other SciDAC software is presented

  6. Status of the MAGIC telescopes

    Energy Technology Data Exchange (ETDEWEB)

    Colin, Pierre; Carmona, Emiliano; Schweizer, Thomas; Sitarek, Julian [Max-Planck-Institut fuer Physik, Werner-Heisenberg Institut, Muenchen (Germany)

    2010-07-01

    MAGIC is a system of two 17-m Cherenkov telescopes located on La Palma (Canary islands),sensitive to gamma-rays above 30 GeV. It has been recently upgraded by a second telescope which strongly improves the sensitivity, particularly at low energy. Here we present the status of the MAGIC telescopes and an overview of the recent results obtained in single or stereoscopic mode. We also discuss the real performance of the new stereoscopic system based on Crab Nebula observations.

  7. Service Level Status

    CERN Multimedia

    Lopienski, S

    2007-01-01

    Nowadays, IT departments provide, and people use, computing services of an increasingly heterogeneous nature. There is thus a growing need for a status display that groups these different services and reports status and availability in a uniform way. The Service Level Status (SLS) system addresses these needs by providing a web-based display that dynamically shows availability, basic information and statistics about various IT services, as well as the dependencies between them.

  8. SIS - Status Determination

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Status Determination dataset within the Species Information System (SIS) contains information related to overfishing, overfished, and approaching overfished...

  9. Pediatric Status Epilepticus Management

    Science.gov (United States)

    Abend, Nicholas S; Loddenkemper, Tobias

    2014-01-01

    Purpose of Review This review discusses management of status epilepticus in children including both anticonvulsant medications and overall management approaches. Recent Findings Rapid management of status epilepticus is associated with a greater likelihood of seizure termination and better outcomes, yet data indicate there are often management delays. This review discusses an overall management approach aiming to simultaneously identify and manage underlying precipitant etiologies, administer anticonvulsants in rapid succession until seizures have terminated, and identify and manage systemic complications. An example management pathway is provided. Summary Status epilepticus is a common neurologic emergency in children and requires rapid intervention. Having a predetermined status epilepticus management pathway can expedite management. PMID:25304961

  10. Interactions between plasma concentrations of folate and markers of vitamin B12 status with cognitive performance in elderly people not exposed to folic acid fortification: the Hordaland Health Study

    NARCIS (Netherlands)

    Doets, E.L.; Ueland, P.M.; Tell, G.S.; Vollset, S.E.; Nygard, O.K.; Veer, van 't P.; Groot, de C.P.G.M.; Nurk, E.; Refsum, H.; Smith, A.D.; Eussen, S.J.P.M.

    2014-01-01

    A combination of high folate with low vitamin B12 plasma status has been associated with cognitive impairment in a population exposed to mandatory folic acid fortification. The objective of the present study was to examine the interactions between plasma concentrations of folate and vitamin B12

  11. Fighting status inequalities

    DEFF Research Database (Denmark)

    Nielsen, Morten Ebbe Juul; Landes, Xavier

    2016-01-01

    Status inequalities seem to play a fairly big role in creating inequalities in health. This article assumes that there can be good reasons to fight status inequalities in order to reduce inequalities in health. It examines whether the neorepublican ideal of non-dominance does a better job as a th...

  12. Morocco: Country Status Report.

    Science.gov (United States)

    McFerren, Margaret

    A survey of the status of language usage in Morocco begins with an overview of the distribution and usage of Arabic, the official language, the Berber dialects, and French, an unofficial second language. The continuing high status and widespread use of French despite arabization efforts is discussed. A matrix follows that rates these languages and…

  13. Adolescent Weight Status

    DEFF Research Database (Denmark)

    Hjort Kjelldgaard, Heidi; Holstein, Bjørn Evald; Due, Pernille

    2017-01-01

    day) communication with friends through cellphones, SMS messages, or Internet (1.66, 1.03-2.67). In the full population, overweight/obese weight status was associated with not perceiving best friend as a confidant (1.59, 1.11-2.28). No associations were found between weight status and number of close...

  14. Between Status and Contract?

    Directory of Open Access Journals (Sweden)

    Thorsten Keiser

    2013-01-01

    Full Text Available This contribution deals with unfree labour in Germany from the early modern age until the beginning of the 20th century. It presents the main conclusions of a book published in 2013 on this subject in German. Unfree labour is not identified in the first place with slavery or any other labour relationship based on status. Instead, this study aims at an analysis of freedom and coercion in contractual labour relationships. It will be argued that in Germany contractual labour relationships before 1800 were embedded in a legal system that strongly restricted contractual autonomy and aimed at the suppression of free labour markets. The scope of this legislation was to guarantee efficient labour performance, which was not only perceived as being in the personal interest of an employer, but as a fundamental element of the common good. After 1800 the system changed to more incentive-based legislation that established freedom of contract for labour relations. Nevertheless, coercion in order to perform the contractual duties of a work contract remained important for many groups of workers, especially farmhands and industrial workers. The last criminal sanctions for breaches of labour contracts were only abolished in the revolution of 1919. This development shows the difficulties German law had in extending the principles of private law to workers. When a system of free labour was fully established, the issue of unemployment and economic problems, especially in the Weimar Republic, required a new system of protective rules. The history of free market based labour contracts in Germany was therefore very short, with state intervention shi ing from control and coercion to social assistance.

  15. Extent of Surgery Does Not Influence 30-Day Mortality in Surgery for Metastatic Bone Disease

    DEFF Research Database (Denmark)

    Sørensen, Michala Skovlund; Hindsø, Klaus; Hovgaard, Thea Bechmann

    2016-01-01

    describing the extent of the surgical trauma were found to be associated with 30-day mortality. The 30-day mortality in patients undergoing surgery for MBD is highly dependent on the general health status of the patients as measured by the ASA score and the Karnofsky performance status. The extent of surgery......, measured as duration of surgery, blood loss, and degree of bone resection were not associated with 30-day mortality....

  16. The Cost of Collaborating with Climbers of Status Hierarchies

    DEFF Research Database (Denmark)

    Andersen, Kristina Vaarst; Mors, Marie Louise; Jeppesen, Jacob

    Status provides preferential access to resources, as well as favorable judgment, which in turn may lead to increases in performance. Prior work has established that such benefits even spill over between collaboration partners, thus allowing collaboration partners of high status individuals to bask...... individual performance. We argue that collaboration partners’ increased status may divert their allocation of effort and focus to other projects. This in turn may lead to a negative spillover effect for individual performance. These arguments are tested using unique data on scientists collaborating on papers...... in their reflected glory and enjoy status related benefits. Yet, we still know relatively little about the underlying mechanisms that affect how individual performance is affected by changes in the status of collaboration partners. In this paper, we analyze how collaboration partners’ status increase affects...

  17. A disease-specific enteral nutrition formula improves nutritional status and functional performance in patients with head and neck and esophageal cancer undergoing chemoradiotherapy: results of a randomized, controlled, multicenter trial.

    Science.gov (United States)

    Fietkau, Rainer; Lewitzki, Victor; Kuhnt, Thomas; Hölscher, Tobias; Hess, Clemens-F; Berger, Bernhard; Wiegel, Thomas; Rödel, Claus; Niewald, Marcus; Hermann, Robert M; Lubgan, Dorota

    2013-09-15

    In patients with head and neck and esophageal tumors, nutritional status may deteriorate during concurrent chemoradiotherapy (CRT). The aim of this study was to investigate the influence of enteral nutrition enriched with eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on body composition and nutritional and functional status. In a controlled, randomized, prospective, double-blind, multicenter study, 111 patients with head and neck and esophageal cancer undergoing concurrent CRT received either an enteral standard nutrition (control group) or disease-specific enteral nutrition Supportan®-containing EPA+DHA (experimental group) via percutaneous endoscopic gastrostomy. The primary endpoint was the change of body cell mass (BCM) following CRT at weeks 7 and 14 compared with the baseline value. Secondary endpoints were additional parameters of body composition, anthropometric parameters, and nutritional and functional status. The primary endpoint of the study, improvement in BCM, reached borderline statistical significance. Following CRT, patients with experimental nutrition lost only 0.82 ± 0.64 kg of BCM compared with 2.82 ± 0.77 kg in the control group (P = .055). The objectively measured nutritional parameters, such as body weight and fat-free mass, showed a tendency toward improvement, but the differences were not significant. The subjective parameters, in particular the Kondrup score (P = .0165) and the subjective global assessment score (P = .0065) after follow-up improved significantly in the experimental group, compared with the control group. Both enteral regimens were safe and well tolerated. Enteral nutrition with EPA and DHA may be advantageous in patients with head and neck or esophageal cancer by improving parameters of nutritional and functional status during CRT. © 2013 American Cancer Society.

  18. Diet-induced changes in iron and n-3 fatty acid status and associations with cognitive performance in 8-11-year-old Danish children: secondary analyses of the Optimal Well-Being, Development and Health for Danish Children through a Healthy New Nordic Diet School Meal Study

    DEFF Research Database (Denmark)

    Sørensen, Louise Bergmann; Damsgaard, Camilla Trab; Dalskov, Stine-Mathilde

    2015-01-01

    Fe and n-3 long-chain PUFA (n-3 LCPUFA) have both been associated with cognition, but evidence remains inconclusive in well-nourished school-aged children. In the Optimal Well-Being, Development and Health for Danish Children through a Healthy New Nordic Diet (OPUS) School Meal Study, the 3-month...... intervention increased reading performance, inattention, impulsivity and dietary intake of fish and Fe. This study investigated whether the intervention influenced n-3 LCPUFA and Fe status and, if so, explored how these changes correlated with the changes in cognitive performance. The study was a cluster...... analysis of test performances (n 644), which showed two main patterns: 'school performance' and 'reading comprehension'. The latter indicated that children with good reading comprehension were also more inattentive and impulsive (i.e. higher d2-test error%). The intervention improved 'school performance...

  19. Status Epilepticus and Refractory Status Epilepticus Management

    Science.gov (United States)

    Abend, Nicholas S.; Bearden, David; Helbig, Ingo; McGuire, Jennifer; Narula, Sona; Panzer, Jessica A.; Topjian, Alexis; Dlugos, Dennis J.

    2014-01-01

    Status epilepticus (SE) describes persistent or recurring seizures without a return to baseline mental status, and is a common neurologic emergency. SE can occur in the context of epilepsy or may be symptomatic of a wide range of underlying etiologies. The clinician’s aim is to rapidly institute care that simultaneously stabilizes the patient medically, identifies and manages any precipitant conditions, and terminates seizures. Seizure management involves “emergent” treatment with benzodiazepines followed by “urgent” therapy with other anti-seizure medications. If seizures persist then refractory SE is diagnosed and management options include additional anti-seizure medications or infusions of midazolam or pentobarbital. This paper reviews the management of pediatric SE and RSE. PMID:25727508

  20. Management of status epilepticus.

    Science.gov (United States)

    Pichler, M; Hocker, S

    2017-01-01

    Status epilepticus is a neurologic and medical emergency manifested by prolonged seizure activity or multiple seizures without return to baseline. It is associated with substantial medical cost, morbidity, and mortality. There is a spectrum of severity dependent on the type of seizure, underlying pathology, comorbidities, and appropriate and timely medical management. This chapter discusses the evolving definitions of status epilepticus and multiple patient and clinical factors which influence outcome. The pathophysiology of status epilepticus is reviewed to provide a better understanding of the mechanisms which contribute to status epilepticus, as well as the potential long-term effects. The clinical presentations of different types of status epilepticus in adults are discussed, with emphasis on the hospital course and management of the most dangerous type, generalized convulsive status epilepticus. Strategies for the evaluation and management of status epilepticus are provided based on available evidence from clinical trials and recommendations from the Neurocritical Care Society and the European Federation of Neurological Societies. © 2017 Elsevier B.V. All rights reserved.

  1. Systemic inflammation, nutritional status and tumor immune microenvironment determine outcome of resected non-small cell lung cancer.

    Directory of Open Access Journals (Sweden)

    Marco Alifano

    Full Text Available BACKGROUND: Hypothesizing that nutritional status, systemic inflammation and tumoral immune microenvironment play a role as determinants of lung cancer evolution, the purpose of this study was to assess their respective impact on long-term survival in resected non-small cell lung cancers (NSCLC. METHODS AND FINDINGS: Clinical, pathological and laboratory data of 303 patients surgically treated for NSCLC were retrospectively analyzed. C-reactive protein (CRP and prealbumin levels were recorded, and tumoral infiltration by CD8+ lymphocytes and mature dendritic cells was assessed. We observed that factors related to nutritional status, systemic inflammation and tumoral immune microenvironment were correlated; significant correlations were also found between these factors and other relevant clinical-pathological parameters. With respect to outcome, at univariate analysis we found statistically significant associations between survival and the following variables: Karnofsky index, American Society of Anesthesiologists (ASA class, CRP levels, prealbumin concentrations, extent of resection, pathologic stage, pT and pN parameters, presence of vascular emboli, and tumoral infiltration by either CD8+ lymphocytes or mature dendritic cells and, among adenocarcinoma type, tumor grade (all p285 mg/L prealbumin levels and high (>96/mm2 CD8+ cell count had a 5-year survival rate of 80% [60.9-91.1] as compared to 18% [7.9-35.6] in patients with an opposite pattern of values. When stages I-II were considered alone, the prognostic significance of these factors was even more pronounced. CONCLUSIONS: Our data show that nutrition, systemic inflammation and tumoral immune contexture are prognostic determinants that, taken together, may predict outcome.

  2. Le statut politique des petits territoires insulaires à vocation touristique a-t’il une influence sur leur performance économique et sociale ? Approche comparative Does political status of small island tourist economies have an influence on their economic and social performance ? Comparative approach

    Directory of Open Access Journals (Sweden)

    Louis Dupont

    2012-05-01

    Full Text Available Le paradigme du développement dans les Petites Economies Insulaires se définit par divers facteurs. Parmi ces derniers figurent entre-autres, le statut politique et le niveau de développement touristique atteint par ces territoires. Cette étude, en croisant diverses analyses a pour but d’évaluer et de comparer empiriquement à l’aide de vingt-cinq indicateurs socio-économiques et démographiques, l’influence de différentes variables et plus particulièrement de celle relative au statut politique sur la performance économique et sociale de deux groupes de territoires, l’un composé de seize petits espaces insulaires de la Caraïbe et du Pacifique, politiquement dépendants et l’autre, de dix-neuf îles des mêmes régions qui ont accédé à la souveraineté. D’une part, les résultats montrent que : comme variable explicative, le statut politique associé à d’autres facteurs intervient pour les deux-tiers dans la performance économique et sociale de ces îles. D’autre part, ils indiquent que les territoires insulaires politiquement dépendants sont économiquement plus prospères, socialement plus avancés, et démographiquement d’une plus grande maturité que ceux ayant acquis leur souveraineté. Toutefois, ces résultats ne doivent en aucun cas être interprétés comme des arguments contre la décolonisation, qui demeure une démarche moralement et universellement soutenable. Enfin, ils montrent également que les îles dépendantes qui bénéficient d’une large autonomie politique affichent en moyenne des résultats économiques et sociaux bien meilleurs que celles qui restent politiquement et centralement très liées à leur métropole, cas notamment de la Guadeloupe et de la Martinique pour lesquelles, en guise d’illustration nous proposons dans le cadre de leur probable évolution statutaire, un modèle de gouvernance qui, au plan politique soit le mieux adapté aux caractéristiques socio-économiques et

  3. STATUS GIZI DAN STATUS KESEHATAN SUKU BADUY

    Directory of Open Access Journals (Sweden)

    Faisal Anwar

    2012-03-01

    Full Text Available 800x600 Normal 0 false false false IN X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Calibri","sans-serif"; mso-bidi-font-family:"Times New Roman";} The objectives of the study were: (1 To analyze the socio-economic and demographic characteristics of Baduy people; (2 To analyze the health status and nutritional status of Baduy people and its influential factors. This research is an explorative and descriptive study on the socio-cultural aspects of food system. The data were collected through a direct interview and discussion with respondents as well as a direct observation at the location of respondents. A sample size of 338 households was drawn from the population. To obtain the data on the cultural aspects, history and  socio aspect of food, in-depth interviews was conducted with 19 key persons. The study was last for 12 months. In Outer Baduy, the factors significantly related to nutritional status are age, number of household size, income, nutritional knowledge, and wife’s ability to read. In Moslem Baduy, only age and income are related to the nutritional status of children. In Moslem Baduy and the Outer Baduy, the correlation between age and W/A or W/H is similar: namely, the higher the age, the lower would the Z-score for the W/A or W/H. The income is significantly correlated to the child nutritional status according to Z-score for W/A with a high correlation coefficient, that is, 0.61. This means that the higher the income, the higher would be the Z-score value for the W/A.  The distribution of adults according to BMI classification in Outer Baduy it shows that 12.7% husbands and 17.6% wives are thin (wasted, while the

  4. Importance of the mini-mental status examination in the treatment of patients with brain metastases: a report from the radiation therapy oncology group protocol 91-04

    International Nuclear Information System (INIS)

    Murray, Kevin J.; Scott, Charles; Zachariah, Babu; Michalski, Jeff M.; Demas, William; Vora, Nayana L.; Whitton, Anthony; Movsas, Benjamin

    2000-01-01

    Purpose: Little information is available on the importance of pretreatment Mini-Mental Status Exam (MMSE) on long-term survival and neurologic function following treatment for unresectable brain metastases. This study examines the importance of the MMSE in predicting outcome in a group of patients treated with an accelerated fractionation regimen of 30 Gy in 10 daily fractions in 2 weeks. Materials and Methods: The Radiation Therapy Oncology Group (RTOG) accrued 445 patients to a Phase III comparison of accelerated hyperfractionated (AH) radiotherapy (1.6 Gy b.i.d.) to a total dose of 54.4 Gy vs. an accelerated fractionation (AF) of 30 Gy in 10 daily fractions from 1991 through 1995. All patients had histologic proof of malignancy at the primary site. Brain metastases were measurable by CT or MRI scan and all patients had a Karnofsky performance score (KPS) of at least 70 and a neurologic function classification of 1 or 2. Two hundred twenty-four patients were entered on the accelerated fractionated arm, and 182 were eligible for analysis (7 patients were judged ineligible, no MMSE information in 29, no survival data in 1, no forms submitted in 1). Results: Average age was 60 years; 58% were male and 25% had a single intracranial lesion on their pretherapy evaluation. KPS was 70 in 32%, 80 in 31%, 90 in 29%, and 100 in 14%. The average MMSE was 26.5, which is the lower quartile for normal in the U.S. population. The range of the MMSE scores was 11-30 with 30 being the maximum. A score of less than 23 indicates possible dementia, which occurred in 16% of the patients prior to treatment. The median time from diagnosis to treatment was 5 days (range, 0-158 days). The median survival was 4.2 months with a 95% confidence interval of 3.7-5.1 months. Thirty-seven percent of the patients were alive at 6 months, and 17% were alive at 1 year. The following variables were examined in a Cox proportional-hazards model to determine their prognostic value for overall survival

  5. Deadline Compliance Status Reports

    Data.gov (United States)

    Department of Housing and Urban Development — These monthly Deadline Compliance Status Reports assist Participating Jurisdictions and HUD Field Offices in monitoring compliance with the 2-year commitment and...

  6. Topical report review status

    International Nuclear Information System (INIS)

    1982-08-01

    A Topical Report Review Status is scheduled to be published semi-annually. The primary purpose of this document is to provide periodic progress reports of on-going topical report reviews, to identify those topical reports for which the Nuclear Regulatory Commission (NRC) staff review has been completed and, to the extent practicable, to provide NRC management with sufficient information regarding the conduct of the topical report program to permit taking whatever actions deemed necessary or appropriate. This document is also intended to be a source of information to NRC Licensing Project Managers and other NRC personnel regarding the status of topical reports which may be referenced in applications for which they have responsibility. This status report is published primarily for internal NRC use in managing the topical report program, but is also used by NRC to advise the industry of report review status

  7. Topical report review status

    International Nuclear Information System (INIS)

    1983-01-01

    A Topical Report Review Status is scheduled to be published semi-annually. The primary purpose of this document is to provide periodic progress reports of on-going topical report reviews, to identify those topical reports for which the Nuclear Regulatory Commission (NRC) staff review has been completed and, to the extent practicable, to provide NRC management with sufficient information regarding the conduct of the topical report program to permit taking whatever actions deemed necessary or appropriate. This document is also intended to be a source of information to NRC Licensing Project Managers and other NRC personnel regarding the status of topical reports which may be referenced in applications for which they have responsibility. This status report is published primarily for internal NRC use in managing the topical report program, but is also used by NRC to advise the industry of report review status

  8. PRESENT STATUS IN INDIA

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. PRESENT STATUS IN INDIA. FIXED LINES – 36 MILLION. MOBILE CONNECTIONS – 14 MILLION. TELEDENSITY APPROXIMATELY 5. INTERNET CONNECTIONS – 5 MILLION. INTERNET USERS NEARLY – 25 MILLION.

  9. NAIP Status Maps Gallery

    Data.gov (United States)

    Farm Service Agency, Department of Agriculture — NAIP Status Maps Gallery. These maps illustrate what aerial imagery collection is planned, whats been collected, when it is available and how it is available. These...

  10. Hierarchy and social status in Budongo chimpanzees.

    Science.gov (United States)

    Newton-Fisher, Nicholas E

    2004-04-01

    The status hierarchy is fundamental in the lives of male chimpanzees. This study describes the dominance interactions and social status among adult male chimpanzees of the Sonso community in the Budongo Forest Reserve, Uganda, during the period that they were first studied (1994 and 1995). Social dominance is typically measured using the behaviour of either the subordinate or the dominant individual, but a relationship is dependent on the behaviour of both parties and this study explicitly used both subordinate and dominant behaviours to investigate the status hierarchy. Among adult males of the Sonso community, agonistic interactions occurred at a low rate and pant-grunts were rare, but males could be ranked into separate hierarchies of agonistic dominance and pant-grunting (labelled 'respect') using ratios of behaviour performed/behaviour received. These hierarchies were combined to form a single hierarchy of social status that divided the males among five distinct status levels. The highest status level was held by an alliance between two males who replaced the previous alpha male during the first part of the study. Neither male in this alliance partnership pant-grunted to the other, although the reason for cooperative behaviour was unclear. Although the nominally beta male was treated as such by other adult males, he achieved surprisingly little mating success. Budongo Forest chimpanzees do not warrant the sometimes-expressed view that they are non-aggressive and peaceable and the broad pattern of their status interactions matches with that seen in other chimpanzee populations.

  11. Safety system status monitoring

    International Nuclear Information System (INIS)

    Lewis, J.R.; Morgenstern, M.H.; Rideout, T.H.; Cowley, P.J.

    1984-03-01

    The Pacific Northwest Laboratory has studied the safety aspects of monitoring the preoperational status of safety systems in nuclear power plants. The goals of the study were to assess for the NRC the effectiveness of current monitoring systems and procedures, to develop near-term guidelines for reducing human errors associated with monitoring safety system status, and to recommend a regulatory position on this issue. A review of safety system status monitoring practices indicated that current systems and procedures do not adequately aid control room operators in monitoring safety system status. This is true even of some systems and procedures installed to meet existing regulatory guidelines (Regulatory Guide 1.47). In consequence, this report suggests acceptance criteria for meeting the functional requirements of an adequate system for monitoring safety system status. Also suggested are near-term guidelines that could reduce the likelihood of human errors in specific, high-priority status monitoring tasks. It is recommended that (1) Regulatory Guide 1.47 be revised to address these acceptance criteria, and (2) the revised Regulatory Guide 1.47 be applied to all plants, including those built since the issuance of the original Regulatory Guide

  12. Safety system status monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, J.R.; Morgenstern, M.H.; Rideout, T.H.; Cowley, P.J.

    1984-03-01

    The Pacific Northwest Laboratory has studied the safety aspects of monitoring the preoperational status of safety systems in nuclear power plants. The goals of the study were to assess for the NRC the effectiveness of current monitoring systems and procedures, to develop near-term guidelines for reducing human errors associated with monitoring safety system status, and to recommend a regulatory position on this issue. A review of safety system status monitoring practices indicated that current systems and procedures do not adequately aid control room operators in monitoring safety system status. This is true even of some systems and procedures installed to meet existing regulatory guidelines (Regulatory Guide 1.47). In consequence, this report suggests acceptance criteria for meeting the functional requirements of an adequate system for monitoring safety system status. Also suggested are near-term guidelines that could reduce the likelihood of human errors in specific, high-priority status monitoring tasks. It is recommended that (1) Regulatory Guide 1.47 be revised to address these acceptance criteria, and (2) the revised Regulatory Guide 1.47 be applied to all plants, including those built since the issuance of the original Regulatory Guide.

  13. LHC Status and Upgrade Challenges

    Science.gov (United States)

    Smith, Jeffrey

    2009-11-01

    The Large Hadron Collider has had a trying start-up and a challenging operational future lays ahead. Critical to the machine's performance is controlling a beam of particles whose stored energy is equivalent to 80 kg of TNT. Unavoidable beam losses result in energy deposition throughout the machine and without adequate protection this power would result in quenching of the superconducting magnets. A brief overview of the machine layout and principles of operation will be reviewed including a summary of the September 2008 accident. The current status of the LHC, startup schedule and upgrade options to achieve the target luminosity will be presented.

  14. Effectiveness of radiation therapy for metastatic spinal tumors producing neurologic impairment

    International Nuclear Information System (INIS)

    Yamamoto, Shuichiro; Nomoto, Satoshi; Imada, Hajime; Nakata, Hajime

    2002-01-01

    The purpose of this study was to evaluate the efficacy of radiation therapy (RT) for treating neurological impairment and improving quality of life (QOL) in patients with metastatic spinal tumors. From 1985 through 2001, 75 patients with metastatic spinal tumors were treated with RT. Neurologic status and Karnofsky performance status were assessed before and after RT. The rate of neurologic improvement was significantly higher in patients with radio-sensitive tumors (75%) than in patients with radio-resistant tumors (37%). Few patients with Karnofsky performance status less than 40% before RT had good QOL after RT. The response to RT did not differ significantly on the basis of duration of paralysis before RT. RT is useful for treating neurologic impairment caused by metastatic spinal tumors, particularly those that are radiosensitive. To have good QOL after RT, treatment should be started in the early stage of neurological impairment. (author)

  15. Service level status-a new real-time status display for IT services

    Energy Technology Data Exchange (ETDEWEB)

    Lopienski, S [IT Department, FIO group CERN, European Organization for Nuclear Research, 1211 Geneve 23 (Switzerland)], E-mail: Sebastian.Lopienski@cern.ch

    2008-07-15

    Nowadays, IT departments provide, and people use, computing services of an increasingly heterogeneous nature. There is thus a growing need for a status display that groups these different services and reports their status and availability in a uniform way. The Service Level Status (SLS) system addresses these needs by providing a web-based display that dynamically shows availability, basic information and statistics about various IT services, as well as the dependencies between them. This paper first introduces the requirements SLS had to meet, and the main concepts behind it, like service availability and status, Key Performance Indicators (KPIs), sub/meta-services, and service dependencies. It then describes the SLS system architecture, and some interesting implementation details, such as the usage of XML Schemas. Since clear visualization of service availability and status is one of the main goals of SLS, emphasis is put on describing the intuitive web-based user interface.

  16. Service level status-a new real-time status display for IT services

    International Nuclear Information System (INIS)

    Lopienski, S

    2008-01-01

    Nowadays, IT departments provide, and people use, computing services of an increasingly heterogeneous nature. There is thus a growing need for a status display that groups these different services and reports their status and availability in a uniform way. The Service Level Status (SLS) system addresses these needs by providing a web-based display that dynamically shows availability, basic information and statistics about various IT services, as well as the dependencies between them. This paper first introduces the requirements SLS had to meet, and the main concepts behind it, like service availability and status, Key Performance Indicators (KPIs), sub/meta-services, and service dependencies. It then describes the SLS system architecture, and some interesting implementation details, such as the usage of XML Schemas. Since clear visualization of service availability and status is one of the main goals of SLS, emphasis is put on describing the intuitive web-based user interface

  17. Refractory status epilepticus

    Directory of Open Access Journals (Sweden)

    Sanjay P Singh

    2014-01-01

    Full Text Available Refractory status epilepticus is a potentially life-threatening medical emergency. It requires early diagnosis and treatment. There is a lack of consensus upon its semantic definition of whether it is status epilepticus that continues despite treatment with benzodiazepine and one antiepileptic medication (AED, i.e., Lorazepam + phenytoin. Others regard refractory status epilepticus as failure of benzodiazepine and 2 antiepileptic medications, i.e., Lorazepam + phenytoin + phenobarb. Up to 30% patients in SE fail to respond to two antiepileptic drugs (AEDs and 15% continue to have seizure activity despite use of three drugs. Mechanisms that have made the treatment even more challenging are GABA-R that is internalized during status epilepticus and upregulation of multidrug transporter proteins. All patients of refractory status epilepticus require continuous EEG monitoring. There are three main agents used in the treatment of RSE. These include pentobarbital or thiopental, midazolam and propofol. RSE was shown to result in mortality in 35% cases, 39.13% of patients were left with severe neurological deficits, while another 13% had mild neurological deficits.

  18. Refractory status epilepticus

    Science.gov (United States)

    Singh, Sanjay P; Agarwal, Shubhi; Faulkner, M

    2014-01-01

    Refractory status epilepticus is a potentially life-threatening medical emergency. It requires early diagnosis and treatment. There is a lack of consensus upon its semantic definition of whether it is status epilepticus that continues despite treatment with benzodiazepine and one antiepileptic medication (AED), i.e., Lorazepam + phenytoin. Others regard refractory status epilepticus as failure of benzodiazepine and 2 antiepileptic medications, i.e., Lorazepam + phenytoin + phenobarb. Up to 30% patients in SE fail to respond to two antiepileptic drugs (AEDs) and 15% continue to have seizure activity despite use of three drugs. Mechanisms that have made the treatment even more challenging are GABA-R that is internalized during status epilepticus and upregulation of multidrug transporter proteins. All patients of refractory status epilepticus require continuous EEG monitoring. There are three main agents used in the treatment of RSE. These include pentobarbital or thiopental, midazolam and propofol. RSE was shown to result in mortality in 35% cases, 39.13% of patients were left with severe neurological deficits, while another 13% had mild neurological deficits. PMID:24791086

  19. Repository development status in Spain

    Energy Technology Data Exchange (ETDEWEB)

    Rodriguez Beceiro, Alvaro; Zuloaga, Pablo [ENRESA (Spain)

    2009-06-15

    The paper describes the status of repository development for the different waste cate