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Sample records for kaiseki eno oyo

  1. Ultimate strength analysis of thin plated structures using eigen-functions. 3rd Report. Application to reliability analysis; Koyu kansu wo mochiita usuita kozobutsu no dansosei kaisekiho. 3. Shinraisei kaiseki eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Ueda, Y. [Osaka University, Osaka (Japan). Welding Research Institute; Masaoka, K.; Okada, H. [University of Osaka Prefecture, Osaka (Japan). Faculty of Engineering

    1996-12-31

    A reliability analysis was performed on ultimate strength of a hull by introducing reliability engineerings into the idealized structural unit method. Elements developed under the present study were applied to a model of an actual structure to indicate that even an analysis requiring much time under the finite element method can be performed in a short time and at high accuracy when this method is used. Analysis acted with bending moment and shear force simultaneously was performed on a model used as a structure in experiments carried out by Nishihara, assuming pure bending moment and longitudinal strength during slamming. Then, a reliability analysis was conducted on the same model based on this analysis method to investigate the ultimate strength. In an analysis of an ultimate strength when bending and shearing that assume slamming act upon simultaneously, axial force in the hull side decreases as loading increases, wherein how the shearing force increases can be identified clearly. Although existence of initial bends reduces the strength, the effect of variance in the vicinity of the average value on the reliability is rather small, while the effect due to variance in yield stress is greater. 27 refs., 14 figs., 4 tabs.

  2. Ultimate strength analysis of thin plated structures using eigen-functions. 3rd Report. Application to reliability analysis; Koyu kansu wo mochiita usuita kozobutsu no dansosei kaisekiho. 3. Shinraisei kaiseki eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Ueda, Y [Osaka University, Osaka (Japan). Welding Research Institute; Masaoka, K; Okada, H [University of Osaka Prefecture, Osaka (Japan). Faculty of Engineering

    1997-12-31

    A reliability analysis was performed on ultimate strength of a hull by introducing reliability engineerings into the idealized structural unit method. Elements developed under the present study were applied to a model of an actual structure to indicate that even an analysis requiring much time under the finite element method can be performed in a short time and at high accuracy when this method is used. Analysis acted with bending moment and shear force simultaneously was performed on a model used as a structure in experiments carried out by Nishihara, assuming pure bending moment and longitudinal strength during slamming. Then, a reliability analysis was conducted on the same model based on this analysis method to investigate the ultimate strength. In an analysis of an ultimate strength when bending and shearing that assume slamming act upon simultaneously, axial force in the hull side decreases as loading increases, wherein how the shearing force increases can be identified clearly. Although existence of initial bends reduces the strength, the effect of variance in the vicinity of the average value on the reliability is rather small, while the effect due to variance in yield stress is greater. 27 refs., 14 figs., 4 tabs.

  3. Ifa Divination Trays from Isale-Oyo

    OpenAIRE

    Pogoson, O. I.; Akande, A. O.

    2016-01-01

    This paper is a study of the images and patterns on ifa divination trays from Isale-Oyo. The paper also explains some ifa paraphernalia. The paper establishes that ifa trays from Isale-Oyo bear distinctive features when compared with other ifa trays in Yorubaland such as those of Ijebu and Osogbo. Central to this study is the iconographic description and interpretations of Isale-Oyo divination trays. Data were collected through direct interviews with divination tray owners. Photographs of ...

  4. Ifa Divination Trays from Isale-Oyo

    Directory of Open Access Journals (Sweden)

    O. I. Pogoson

    2011-10-01

    Full Text Available This paper is a study of the images and patterns on ifa divination trays from Isale-Oyo. The paper also explains some ifa paraphernalia. The paper establishes that ifa trays from Isale-Oyo bear distinctive features when compared with other ifa trays in Yorubaland such as those of Ijebu and Osogbo. Central to this study is the iconographic description and interpretations of Isale-Oyo divination trays. Data were collected through direct interviews with divination tray owners. Photographs of the trays were also taken. The investigation revealed that:Divination trays from Isale-Oyo combine features found on both Ijebu and Osogbo trays.The Esu figure continues to occupy the top central position on Oyo divination trays, even though with representational variations elsewhere in Yorubaland.Some divination trays in Oyo carry no decorations on their borders, and in some recent cases, ceramic plates are now used for divination.Este artigo trata dos padrões e imagens dos tabuleiros de adivinhação ifa usados em Isale-Oyo (Nigéria, bem como de outros objectos religiosos associados. Argumenta-se que os tabuleiros ifa de Isale-Oyo têm características que os distinguem de outros tabuleiros ifa da região yoruba, como os de Ijebu e Osogbo. A descrição e a interpretação da iconografia dos tabuleiros de adivinhação constituem o foco deste estudo. Os dados discutidos foram recolhidos através de entrevistas a proprietários de tabuleiros de adivinhação e fotografias de tabuleiros. Conclui-se que:Os tabuleiros de adivinhação de Isale-Oyo combinam traços dos tabuleiros de Ijebu e dos tabuleiros de Osogbo.A figura de Esu continua a ocupar a posição central superior nos tabuleiros de adivinhação de Oyo, embora se registem variações na sua representação noutras zonas do território yoruba.Alguns tabuleiros de adivinhação de Oyo não possuem qualquer decoração nos frisos, e nalguns casos recentes vêm sendo utilizados na adivinhação pratos

  5. Winning strategies: A case study of Oyo State Lottery, Nigeria ...

    African Journals Online (AJOL)

    In this study, we investigated three common lottery strategies: random, low and high frequency strategies, usually employed by lottery players. The Oyo State Lottery, a type of lottery in Oyo State, Nigeria was used as a case study. For the three strategies, we considered whether the selection of numbers in Oyo State lottery ...

  6. Sorption mechanism of solvent vapors to coals; Sekitan eno yobai joki no shuchaku kiko no kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Shimizu, K.; Takanohashi, T.; Iino, M. [Tohoku University, Sendai (Japan). Institute for Chemical Reaction Science

    1996-10-28

    With an objective to clarify the interactions between micropore structure of coal and solvent reagents, a sorption experiment was carried out under solvent saturated vapor pressure. Low-volatile bituminous coal, Pocahontas No. 3 coal, has the aromatic ring structure developed, and makes solvent more difficult to diffuse into coal, hence sorption amount is small. Methanol has permeated since its polarity is high. High-volatile bituminous coal, Illinois No. 6 coal, makes solvent penetrate easily, and the sorption amount was large with both of aromatic and polar solvents. Since brown coal, Beulah Zap coal, contains a large amount of oxygen, and hydrogen bonding is predominant, sorption amount of cyclohexane and benzene having no polarity is small. Methanol diffuses while releasing hydrogen bond due to its polarity, and its sorption amount is large. A double sorption model is available, which expresses the whole sorption amount as a sum of physical sorption amount and amount of permeation into coal. This model was applied when it explained successfully the sorption behavior of the solvents relative to coals, excepting some of the systems. However, also observed were such abnormal behavior as sorption impediment due to interactions between coal surface and solvents, and permeation impediment due to hydroxyl groups inside the coals. 1 ref., 10 figs., 2 tabs.

  7. Application of FEM flow analysis to environmental engineering. FEM ryutai kaiseki no kankyo gijutsu eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Higuchi, M; Ando, K; Shimada, S; Umetani, H [Toyota Motor Corp., Aichi (Japan)

    1990-04-25

    In order to apply FEM (finite element method) flow analysis to environmental engineering, the two-dimensional analysis system was developed, and applied to the design of plant ventilation and improvement of an enviromental control equipment. Furthermore, the three-dimensional analysis system was developed to extend its application. Since in a large scale model, no enhancement of a processing capacity was expected even by a supercomputer because of longer I/O times between internal and external memories caused by a small internal memory space, the parallel processing system with multiple external memories was introduced to analyze such models. To achieve more efficient processing, multiple series of renumbering codes were also prepared to optimize the processing order of solvers, elements and nodes. As examples, the improvement of a thermal oxidizer and the ventilation design for a forging plant, and as an example of a three-dimensional large scale model, the flow analysis around a plant were presented. 8 refs., 17 figs., 1 tab.

  8. Determinants of production level of commercial snail farmers in Oyo ...

    African Journals Online (AJOL)

    The study investigates the determinants of productivity level among commercial snail farmers in Oyo State. A systematic sampling technique was employed to select one-hundred and forty–two snail farmers from the membership list provided by the Snail Farmers Association of Nigeria (SFAN), Oyo State Chapter.

  9. Application of thermal spray coatings for jet engines. Kokuki sangyo eno yosha no oyo

    Energy Technology Data Exchange (ETDEWEB)

    Muto, Y [All Nippon Airways Co. Ltd., Tokyo (Japan)

    1992-10-31

    Application condition of spray coating on jet engine parts and characteristics of spray reparing process are explained. Spray coating used for jet engine is classified as recovery of dimension, crevice adjustment, improvement of resistance to friction, improvement of fretting resistance and heat resistance. Titanium alloy having better adhesion and acid resistance, is used as coating for dimensional recovery, where as nickel-crome-aluminium coating is used for the improvement of heat resistance of stainless steel, etc. Crevice adjustment coatings are used in rotating parts of jet engines, and they are of two types are; gel-double coating of aluminium, nickel-aluminium, etc., abrasive coating of aluminium oxide. Tungsten carbide and cobalt are used as coatings for the friction improvement. Nickel and indium, etc., are used as fretting resistance coating. Various types of ceramics together with heat resistance steels like HS-188 are used as coating for heat resistance improvement. 4 figs., 3 tabs.

  10. Determinants of job effectiveness of extension personnel in Oyo ...

    African Journals Online (AJOL)

    Determinants of job effectiveness of extension personnel in Oyo state ADP and ... such ass age, gender, educational qualification, income and year of experience. ... Incentives to job effectiveness was taken on Very High Satisfaction, High ...

  11. Stress coping strategies among agricultural extension agents in Oyo ...

    African Journals Online (AJOL)

    Stress coping strategies among agricultural extension agents in Oyo State, Nigeria. ... Journal Home > Vol 20, No 1 (2016) >. Log in or ... Employees should have control over work flow to reduce work stress and increase work efficiency.

  12. Economics of duck marketing in Oyo State | Saka | African Journal of ...

    African Journals Online (AJOL)

    Economics of duck marketing in Oyo State. ... The marketing survey involved 50 duck traders selected from Ibadan, Oyo and Ogbomoso. Majority (72%) of the marketers procured ... EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL ...

  13. Estimation of Magnetic Basement Depth of Oyo Area from ...

    African Journals Online (AJOL)

    Locations and depths to magnetic contacts were estimated from the total intensity magnetic field using Horizontal gradient magnitude (HGM), Analytic signal amplitude (ASA) and Local wavenumber (LWN). The digitized magnetic intensity data of Oyo area, south western Nigeria was analyzed to estimate depths to magnetic ...

  14. Modeling Selected Climatic Variables in Ibadan, Oyo State, Nigeria ...

    African Journals Online (AJOL)

    PROF. O. E. OSUAGWU

    2013-09-01

    Sep 1, 2013 ... The aim of this study was fitting the modified generalized burr density function to total rainfall and temperature data obtained from the meteorological unit in the Department of. Environmental Modelling and Management of the Forestry Research Institute of Nigeria. (FRIN) in Ibadan, Oyo State, Nigeria.

  15. Differential Perception of Counselling Psychologists' Duties to Oyo ...

    African Journals Online (AJOL)

    This descriptive survey study investigated the differences that exist in the perception of the relevance of counselling psychologists' duties to broadcasting corporation. The participants consisted of one hundred and two (54 males and 48 females) purposively selected staff of Oyo State Broadcasting Corporation.

  16. Latest trends in variable speed drive systems. ; Application to elevators. Kahensoku drive system no saishin doko. ; Elevator eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Inaba, H. (Hitachi, Ltd., Tokyo (Japan))

    1992-07-12

    The history of the elevator development may be summarized as a challenge to heights of buildings, pursuit of energy saving, and realizing comfort. Transfer of its drive system to the inverter drive system has been nearly completed keeping the pace with advance of electronic technologies. This paper describes control systems of elevators, effects of introducing inverters, and future trends. The inverter system used widely now for standard elevators with a speed lower than 105 m/min consists of a converter to rectify the utility power, a regenerative power consuming circuit to suppress overvoltage in the DC stage, and an inverter to supply power to induction motors. Those elevators exceeding a 120 m/min speed use power regenerating inverter system, with its converter controlled using micro computers according to loads and speeds of motors. The inverter system is particularly marked for having realized energy saving, lower power consumption, lower environmental pollution (from harmonics), comfort and maintainability at high levels. 13 refs., 9 figs.

  17. Introduction of electric double layer capacitors in the solar-EV; Solar denki jidosha eno denki nijuso condenser no oyo

    Energy Technology Data Exchange (ETDEWEB)

    Fujinaka, M [Tokyo Denki University, Tokyo (Japan)

    1996-10-27

    A basic experiment was carried out on a supplementary power supply, in which solar cells and electric double layer capacitors(EDLC) were combined for a DC/DC converter, for the use of a solar-electric vehicle (S-EV); and in actuality, an S-EV was loaded with the power supply with a running test conducted on a public road. The EDLC was found effective and useful for avoiding temporary lowering of voltage and momentary break. An electric supply was thereby made possible for an emergency light without the use of the DC/DC converter. However, in a tunnel or a night driving and in case of failure of the DC/DC converter, an operating time of only 7 minutes or so was affordable with the EDLC having a capacity of 100F. Moreover, particularly with a heavy load, it was impossible to maintain a voltage for many hours. Under the circumstances, an S-EV design would primarily require two sets of independent DC/DC converter loaded in the future. The EDLC, young after it was developed, still has a small energy density compared with a lead storage battery. Yet, an EDLC with a higher performance being developed, there is a possibility that it will be applied to S-EV`s by utilizing its characteristics such as a high efficiency and a long service life. 4 refs., 8 figs.

  18. Application fo tunneling and atomic force detection to machines and scientific instruments. Tunnel gensho ya genshikan no mechatronics eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Kawakatsu, H. (The University of Tokyo, Tokyo (Japan). Institute of Industrial Science)

    1991-11-01

    It is now about ten years since the scanning tunnel microscope (STM) and the atomic force microscope (AFM) were invented. These microscopes are used very importantly today as a surface analyzer capable of atomic order analysis for their very high resolution. The STM and AFM obtain images of atomic orders by means of mechanical scanning of the probes. This means that the microscopes can control positioning, force detection and displacement in regions of sub-nanometer orders. Examples of researches may include detection of acceleration, length measurement, positioning, force detection, nano-tripology, processing and gravitational wave detection. As described above, this paper notes the researches derived from the operational principles of the STM and AFM, rather than the researches on the observation objects. The great diversity of the researches taken up and the greatness in the number of researches in the STM and AFM gather how superbly germinative these were. 34 refs.

  19. Assessment of nutritional status of school children in Oyo West Local ...

    African Journals Online (AJOL)

    Objective: The objective of this study was to assess the nutritional status of primary school children in Oyo West Local Government Area of Oyo State. Materials and Methods: A cross-sectional survey was among 499 primary school children. The study instrument was a pretested interviewer-administered questionnaire.

  20. Elasticities of resource- use in fish production: a case study of Oyo ...

    African Journals Online (AJOL)

    This paper examined the elasticities of resource use in fish production in Oyo agricultural zone, Oyo state. The data used is from a primary source. The instruments of data collection were structured questionnaire and in-depth interview. Multi-stage sampling technique was employed to sample 120 fish farmers. However ...

  1. Perceived Indices of Truancy among Selected Adolescents in Oyo Town: Implications for Behavioural Change

    Science.gov (United States)

    Adika, Lawrence Olagoke

    2016-01-01

    The study investigated perceived indices of truancy behaviour among selected adolescents in Oyo town. The descriptive survey study had 200 randomly selected adolescents from five secondary schools in Oyo town. A self-designed instrument tagged Adolescent Truancy Scale (ATS) was employed in collecting data for the study and the data was subjected…

  2. Assessment of Users Information Needs and Satisfaction in Selected Seminary Libraries in Oyo State, Nigeria

    Science.gov (United States)

    Adekunjo, Olalekan Abraham; Adepoju, Samuel Olusegun; Adeola, Anuoluwapo Odebunmi

    2015-01-01

    The study assessed users' information needs and satisfaction in selected seminary libraries in Oyo State, Nigeria. This paper employed the descriptive survey research design, whereby the expost-facto was employed with a sample size of three hundred (300) participants, selected from six seminaries located in Ibadan, Oyo and Ogbomoso, all in Oyo…

  3. Low shear stress induces vascular eNOS uncoupling via autophagy-mediated eNOS phosphorylation.

    Science.gov (United States)

    Zhang, Jun-Xia; Qu, Xin-Liang; Chu, Peng; Xie, Du-Jiang; Zhu, Lin-Lin; Chao, Yue-Lin; Li, Li; Zhang, Jun-Jie; Chen, Shao-Liang

    2018-05-01

    Uncoupled endothelial nitric oxide synthase (eNOS) produces O 2 - instead of nitric oxide (NO). Earlier, we reported rapamycin, an autophagy inducer and inhibitor of cellular proliferation, attenuated low shear stress (SS) induced O 2 - production. Nevertheless, it is unclear whether autophagy plays a critical role in the regulation of eNOS uncoupling. Therefore, this study aimed to investigate the modulation of autophagy on eNOS uncoupling induced by low SS exposure. We found that low SS induced endothelial O 2 - burst, which was accompanied by reduced NO release. Furthermore, inhibition of eNOS by L-NAME conspicuously attenuated low SS-induced O 2 - releasing, indicating eNOS uncoupling. Autophagy markers such as LC3 II/I ratio, amount of Beclin1, as well as ULK1/Atg1 were increased during low SS exposure, whereas autophagic degradation of p62/SQSTM1 was markedly reduced, implying impaired autophagic flux. Interestingly, low SS-induced NO reduction could be reversed by rapamycin, WYE-354 or ATG5 overexpression vector via restoration of autophagic flux, but not by N-acetylcysteine or apocynin. eNOS uncoupling might be ascribed to autophagic flux blockade because phosphorylation of eNOS Thr495 by low SS or PMA stimulation was also regulated by autophagy. In contrast, eNOS acetylation was not found to be regulated by low SS and autophagy. Notably, although low SS had no influence on eNOS Ser1177 phosphorylation, whereas boosted eNOS Ser1177 phosphorylation by rapamycin were in favor of the eNOS recoupling through restoration of autophagic flux. Taken together, we reported a novel mechanism for regulation of eNOS uncoupling by low SS via autophagy-mediated eNOS phosphorylation, which is implicated in geometrical nature of atherogenesis. Copyright © 2018 Elsevier B.V. All rights reserved.

  4. Crime-Reporting Practices Among Market Women in Oyo, Nigeria

    Directory of Open Access Journals (Sweden)

    Johnson Oluwole Ayodele

    2015-04-01

    Full Text Available Crime surveys of businesses have revealed that while crimes in which men were victims tend to be reported, those in which women were victims are likely to go unreported to the police. Understanding the reasons behind male reporting and female non-reporting is useful not only for collection of crime statistics but also for improving crime control competences of law enforcement agencies. This article examines the impact of crime involving market women on their crime-reporting practices in Oyo town, Oyo State, Nigeria. The study adopted quantitative and qualitative approaches. Copies of a questionnaire were administered to collect quantitative data from randomly selected 210 market women at Akesan, Sabo, and Mosadoba markets in Oyo town. Five focus group discussions, in-depth and key informant interviews were conducted to complement quantitative data. Both data were analyzed. The study found that cultural considerations stand between crime events that hurt the economic interests of women and their readiness to report to the police. Due to the very low confidence that market women have in the ability and willingness of the police to apprehend criminals, they prefer to internalize their losses, take their cases to traditional rulers who use “oro cult” to protect them against criminals, or approach available faith-based options such as churches and mosques. The article concludes that women have economy-enriching roles to play in the context of sustainable security. It therefore suggests that the government should address public safety to enable market women make their modest contribution to Nigeria’s economic development.

  5. oral hygiene status of adolescents in a local government area of oyo

    African Journals Online (AJOL)

    User

    Physical examination was carried out in the oral cavity of adolescents in Ibadan North LGA of. Oyo State Nigeria in ... physical and mental wellbeing, appearance and interpersonal .... More females than male had poor oral hygiene status and.

  6. Brian Eno Hollandi Festivali peakülaliseks

    Index Scriptorium Estoniae

    1999-01-01

    Inglise helilooja, videokunstnik ja muusikaprodutsent Brian Eno on 5.-26. juunini Amsterdamis toimuva avangardse Hollandi Festivali peakülaline, kelle videoinstallatsioon seatakse üles Stedelijki Muuseumis. Festivali programmist

  7. Labour Arrangements in Cassava Production in Oyo State, Nigeria

    Directory of Open Access Journals (Sweden)

    Abila, N.

    2012-01-01

    Full Text Available The study examined the effects of labour arrangements on the profitability of cassava enterprises in Oyo North Area of Oyo State, Nigeria. A multi-stage sampling technique was adopted for data collection, while data were analysed using descriptive statistics and budgetary analysis. The results show that the prevalent labour arrangements for cassava enterprises are: a combination of Family, Hired and Contract labour (38.9%; Family-Hired labour (27.8%; Family-Contract labour (31.1%. The gross margin per hectares across labour arrangements are N279481.99 (all-labour, N286044.24 (family-hired, N216940.10 (familycontract, and N235000.00 (family only. The returns on a naira invested on variable costs across different labour arrangements for cassava enterprises are N2.04 (all-labour, N3.66 (family-hired, N2.37 (familycontract, and N2.61 (family only. This implies that a unit (N1 variable cost in the various labour arrangements of all-labour, family/hired, family/contract and family only in cassava production will yield a marginal return of N3.04, N3.66, N2.37 and N2.61 respectively. Family-hired labour arrangement yields higher marginal return per unit of manday and one naira spent than all other arrangements. The study recommends among others the application of laboursaving technologies and an optimum combination of various labour arrangements to reduce the cost of labour used in cassava production.

  8. Vascular nitric oxide: Beyond eNOS

    Directory of Open Access Journals (Sweden)

    Yingzi Zhao

    2015-10-01

    Full Text Available As the first discovered gaseous signaling molecule, nitric oxide (NO affects a number of cellular processes, including those involving vascular cells. This brief review summarizes the contribution of NO to the regulation of vascular tone and its sources in the blood vessel wall. NO regulates the degree of contraction of vascular smooth muscle cells mainly by stimulating soluble guanylyl cyclase (sGC to produce cyclic guanosine monophosphate (cGMP, although cGMP-independent signaling [S-nitrosylation of target proteins, activation of sarco/endoplasmic reticulum calcium ATPase (SERCA or production of cyclic inosine monophosphate (cIMP] also can be involved. In the blood vessel wall, NO is produced mainly from l-arginine by the enzyme endothelial nitric oxide synthase (eNOS but it can also be released non-enzymatically from S-nitrosothiols or from nitrate/nitrite. Dysfunction in the production and/or the bioavailability of NO characterizes endothelial dysfunction, which is associated with cardiovascular diseases such as hypertension and atherosclerosis.

  9. Numerical analysis of exhaust gas flow during the gas exchange process and the design optimization; Haiki manihorudonai no hiteijo nagare kaiseki gijutsu to sono oyo

    Energy Technology Data Exchange (ETDEWEB)

    Yoshizawa, K; Takeyama, S; Sakai, E; Tanzawa, K [Nissan Motor Co. Ltd., Tokyo (Japan)

    1997-10-01

    A simulation method was developed to estimate exhaust gas flow during the gas exchange process. In this simulation, one dimensional in-cylinder gas flow calculation and three dimensional exhaust gas flow calculation were combined. Gas flow inside the exhaust manifold catalyst during gas exchange was agreed in experiments. A simulation method was applied to select oxygen sensor location. A prediction of the oxygen sensor sensitivity of each cylinder gas was presented. The possibility of selecting oxygen sensor location in the exhaust manifold using calculation was proved. 5 refs., 10 figs., 1 tab.

  10. Non-meritocratic Factors and the Recruitment Process in Oyo State ...

    African Journals Online (AJOL)

    Results show that the dynamics of the recruitment and selection processes in Oyo State civil service are driven more by nonmeritocratic influences such as ethnicity, religion, statism, politicization etc. which have become embedded into the socio-economic and political organization/structure of Nigeria. Merit is undermined ...

  11. Principals' Application of Instructional Leadership Practices for Secondary School Effectiveness in Oyo State

    Science.gov (United States)

    Loyce, Onyali Chiedozie; Victor, Akinfolarin Akinwale

    2017-01-01

    This study ascertained the principals' application of instructional leadership practices for secondary school effectiveness in Oyo State. Two research questions guided the study and two null hypotheses were tested. The descriptive survey research design was adopted for the study. The population of the study comprised 8,701 which were made of 969…

  12. Correlates of Examination Malpractice among Secondary School Students in Oyo State, Nigeria

    Science.gov (United States)

    Animasahun, R. A.; Ogunniran, J. O.

    2014-01-01

    The purpose of this study is to investigate the correlates of examination malpractice among secondary school students in Oyo State, Nigeria. The instrument used for the study was tagged Predisposing Factors towards Examination Malpractice Questionnaire (PFTEMQ). The instrument was administered to 300 students randomly selected from 20 multi staged…

  13. Perceived effects of climate change on food crops production in Oyo ...

    African Journals Online (AJOL)

    The study assessed the perceived effects of climate change on food crops production in Oyo State. Multi stage sampling procedure was used in selecting 120 respondents for the study. Primary data was collected through interview schedule and it was analyzed using both descriptive and inferential statistics. Results reveal ...

  14. Statistical Analysis of Poverty in Oyo-State: A Q -Approach

    African Journals Online (AJOL)

    PROF. OLIVER OSUAGWA

    2014-12-01

    Dec 1, 2014 ... It is in the light of this, that this study was aimed at analyzing poverty in Oyo State ... than 50% of the households lacked access to the pre-selected deprivation indicators with lack .... social, economic and political factors. The.

  15. Statistical Analysis of Poverty in Oyo-State: A Q 2 -Approach ...

    African Journals Online (AJOL)

    The limited scope of uni-dimensional money-metric approach of analyzing poverty based on either expenditure or income has made approaches that allow poverty to be studied at several dimensions a necessity. It is in the light of this, that this study was aimed at analyzing poverty in Oyo State using a Q2-approach.

  16. Domestic Water Utilization and Its Determinants in the Rural Areas of Oyo State, Nigeria Using Multivariate Analysis

    OpenAIRE

    T. O. Ogunbode; I. P. Ifabiyi

    2017-01-01

    Investigation into water utilization and its determinants in the rural areas is salient to a result-oriented management of this resource. Thus, a research was conducted to assess the pattern of domestic water uses and its determinant in the rural areas of Oyo State, Nigeria. A multistage sampling technique was applied to select 124 villages from 25 out of the 33 LGAs in Oyo State, Nigeria with 5 villages from each. Ten structured questionnaire were administered in each of the selected village...

  17. Application to the field of medical and welfare with fluid power; Fluid power servo no iryo fukushi bun`ya eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Hayakawa, Y. [Nara Technical Coll., Nara (Japan)

    1999-05-15

    Reported herein are medical and welfare apparatuses activated by fluid power servos. Reference is also made to equipment now undergoing research and development. Numerous fluid power-driven welfare and caring apparatuses have been developed, some of which are named below. In an externally powered prosthetic leg, a rocking type hydraulic servo actuator is attached on the knee section. In this device, switching is performed between an active operation in which much torque is required for instance going up and down a stairway and a passive operation in which less torque is required for instance walking on a flat place, this for increased energy efficiency. In an externally powered orthosisis, an exoskeleton is installed on the lower extremities of a patient suffering from the paralysis of both legs, and enables physical exercises for rehabilitation. Such devices are controlled by one of the two methods, the master-slave method or the manual method. Devices for the transfer of patients include an in-home bathing assist system, powered assist suit for caring, powered assist chair, movable lift for transfer, pneumatic Rubbertuator-driven rehabilitation equipment, walk training device, and wavy motion pneumatic vibrator. (NEDO)

  18. Application of photo-excitation reaction on titanium oxide thin film for control of wettability; Sanka chitann hakumakujo no hikari reiki hanno no nuresei seigyo eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Watanabe, T.; Nakajima, A.; Hashimoto, K. [The Univ. of Tokyo, Tokyo (Japan); Takada, Y. [Kyushu Univ., Fukuoka (Japan)

    2000-03-31

    It is clarified that the photo-excitation hydrophilic reaction increasing wettability remarkably is induced by changing surface structure of titanium oxide radiated light. There are already many examples being in practical use of coating products applied hydrophilic reaction of titanium oxide surface such as drip-proof side millers for automobiles, self-cleaning building materials, and the like. When surface of titanium oxide having high activities for oxidisation and decomposition is coated organic materials and radiated light, wettability of surface changes as organic materials are decomposed. If it is possible to change wettability shaping pattern drastically by radiating light, the possibility of application for printing materials will be developed. After increasing contact angle by coating water and oil repellent on the titanium oxide thin film, images can be shaped by radiating light into pattern for changing surface of titanium oxide to be ultra hydrophilicity as decomposition of repellent. At that time, contact angle is 150 degree in water, 80 degree in oil, for not radiated aria, and is 0 degree in water and oil for radiated aria. Application for control technology of wettability keeps possibility of broader development to itself, not staying ability of self-cleaning and drip-proof. (NEDO)

  19. Inverse LMI control design method and its application to position keeping system; Gyakumondai LMI seigyokei sekkeiho no kaihatsu to ichi hoji system eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Yamamoto, I; Hayashi, T [Mitsubishi Heavy Industries, Ltd., Tokyo (Japan)

    1997-10-01

    Recently, with a progress of robust control such as H{infinity} control, the application of a control system design considering a robustness of controlled system fluctuation to real machinery became possible. In addition, LMI (Linear Matrix Inequality) control system design method is superior to conventional H{infinity} control, although including various difficult elements. The design algorithm permitting the robust control system design of non-linear problems by giving controlled systems was thus developed by introducing an inverse LMI control design method. This design algorithm determines the solution of models outputting the deviation between a target value and controlled variables by solving the simultaneous equations composed of a linear matrix inequality under an impulse response constraint condition and that under an H{infinity} norm constraint condition. This technique allows to give a pending step response as control condition. The technique was confirmed to be effective by its application to the position keeping control problem of marine floating structures. 6 refs., 11 figs., 2 tabs.

  20. Application of photovoltaic generating system to electric power in large ship; Taiyoko hatsuden system no ogata senpaku eno oyo ni kansuru kento

    Energy Technology Data Exchange (ETDEWEB)

    Katagi, T; Ogawa, S; Nishikawa, E; Hashimoto, T [Kobe University of Mercantile Marine, Kobe (Japan); Ishida, K

    1996-10-27

    This paper describes the design of electric power system in a ship with photovoltaic power generating system, to examine applicability of the photovoltaic power generating system to the inboard power source. It also discusses effectiveness of the system for sea environment. At first, the actual route of a car carrier, meteorological data, and quantity of power consumption were picked up from the deck logbook and engine logbook. Then, the installation area of photovoltaic arrays, the quantity of photovoltaic power generation derived from the quantity of solar radiation, and the capacities of batteries and inverters were calculated, to design the electric power system in the ship with photovoltaic power generation system. Moreover, the NOx and SOx emissions were compared between the present power system and the usual power system using diesel power generator, to discuss the effectiveness of the present system for sea environment. Consequently, it was found that the emission of NOx was reduced by about 33% and the emission of SOx was reduced by about 28% compared to the usual power system. The effectiveness for sea environment was confirmed. 9 refs., 5 figs., 4 tabs.

  1. Application of adaptive control to windmill power system by computer simulation. Simulation ni yoru tekio seigyo no furyoku hatsuden system eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Tomiya, T.; Matsuo, T. (Anan College of Technology, Tokushima (Japan)); Suzuki, T.; Kamano, T. (Tokushima University, Tokushima (Japan). Faculty of Engineering)

    1991-07-20

    A windmill power system using load DC generators having resistive load was subjected to discussions by simulation on development of a control method and its output characteristics to draw out the wind energy effectively even when the system characteristics are unknown. The control method used is a mountaineering method available among adaptive control methods. As a result of discussions, the effectiveness of the mountaineering method was confirmed in controlling the output either when the wind velocity is constant or variable. With respect to the control interval, which is a problem in carrying out a control, it was found that the control output stabilizes as the control interval is increased when the wind velocity is constant, but takes longer time before reaching a steady state output. When the wind velocity is variable, the increased control interval reduces the output slightly because of the load resistance change becoming coarser. It was also revealed that, on simulated natural winds, this control method can draw out more energy than by a fixed load resistance. 7 refs., 11 figs., 1 tab.

  2. Genetic algorithm based on virus theory of evolution for traveling salesman problem; Virus shinkaron ni motozuku identeki algorithm no junkai salesman mondai eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Kubota, N. [Osaka Inst. of Technology, Osaka (Japan); Fukuda, T. [Nagoya University, Nagoya (Japan)

    1998-05-31

    This paper deals with virus evolutionary genetic algorithm. The genetic algorithms (GAs) have been demonstrated its effectiveness in optimization problems in these days. In general, the GAs simulate the survival of fittest by natural selection and the heredity of the Darwin`s theory of evolution. However, some types of evolutionary hypotheses such as neutral theory of molecular evolution, Imanishi`s evolutionary theory, serial symbiosis theory, and virus theory of evolution, have been proposed in addition to the Darwinism. Virus theory of evolution is based on the view that the virus transduction is a key mechanism for transporting segments of DNA across species. This paper proposes genetic algorithm based on the virus theory of evolution (VE-GA), which has two types of populations: host population and virus population. The VE-GA is composed of genetic operators and virus operators such as reverse transcription and incorporation. The reverse transcription operator transcribes virus genes on the chromosome of host individual and the incorporation operator creates new genotype of virus from host individual. These operators by virus population make it possible to transmit segment of DNA between individuals in the host population. Therefore, the VE-GA realizes not only vertical but also horizontal propagation of genetic information. Further, the VE-GA is applied to the traveling salesman problem in order to show the effectiveness. 20 refs., 10 figs., 3 tabs.

  3. Suitability assessment and mapping of Oyo State, Nigeria, for rice cultivation using GIS

    Science.gov (United States)

    Ayoade, Modupe Alake

    2017-08-01

    Rice is one of the most preferred food crops in Nigeria. However, local rice production has declined with the oil boom of the 1970s causing demand to outstrip supply. Rice production can be increased through the integration of Geographic Information Systems (GIS) and crop-land suitability analysis and mapping. Based on the key predictor variables that determine rice yield mentioned in relevant literature, data on rainfall, temperature, relative humidity, slope, and soil of Oyo state were obtained. To develop rice suitability maps for the state, two MCE-GIS techniques, namely the Overlay approach and weighted linear combination (WLC), using fuzzy AHP were used and compared. A Boolean land use map derived from a landsat imagery was used in masking out areas currently unavailable for rice production. Both suitability maps were classified into four categories of very suitable, suitable, moderate, and fairly moderate. Although the maps differ slightly, the overlay and WLC (AHP) approach found most parts of Oyo state (51.79 and 82.9 % respectively) to be moderately suitable for rice production. However, in areas like Eruwa, Oyo, and Shaki, rainfall amount received needs to be supplemented by irrigation for increased rice yield.

  4. Crataegus Special Extract WS 1442 Effects on eNOS and microRNA 155.

    Science.gov (United States)

    Wang, Xinwen; Liang, Yan; Shi, Jian; Zhu, Hao-Jie; Bleske, Barry E

    2018-04-16

    Increased expression of microRNA 155 (miR-155) results in a decrease in endothelial nitric oxide synthase (eNOS) expression and impaired endothelial function. Factors that have been shown to increase expression of miR-155 may be mitigated by WS 1442, an extract of hawthorn leaves and flowers ( Crataegus special extract) that contains a range of pharmacologically active substances including oligomeric proanthocyanidins and flavonoids. The purpose of this study is to determine the effect of WS 1442 on the expression of miR-155 and eNOS in the presence of tumor necrosis factor (TNF- α ). Human umbilical vein endothelial cells (HUVECs) were studied after the exposure to TNF- α , with or without simvastatin (positive control) and WS 1442. The expression levels of eNOS, phosphorylated eNOS, and miR-155 in the different HUVEC treatment groups were determined by western blot and quantitative real-time polymerase chain reaction, respectively. To evaluate the effect of WS 1442 on the eNOS activity, the medium and intracellular nitrate/nitrite (NO) concentrations were also analyzed using a colorimetric Griess assay kit. The results demonstrated that TNF- α upregulated miR-155 expression and decreased eNOS expression and NO concentrations. WS 1442 also increased miR-155 expression and decreased eNOS expression but, unlike TNF- α , increased phosphorylated eNOS expression and NO concentrations. Surprisingly, WS 1442 increased miR-155 expression; however, WS 1442 mitigated the overall negative effect of miR-155 on decreasing eNOS expression by increasing expression of phosphorylated eNOS and resulting in an increase in NO concentrations. In the setting where miR-155 may be expressed, WS 1442 may offer vascular protection by increasing the expression of phosphorylated eNOS. Georg Thieme Verlag KG Stuttgart · New York.

  5. Association between nucleotide mutation of eNOS gene and serum ...

    African Journals Online (AJOL)

    Various mutation on endothelial nitric oxide synthase (eNOs) gene cause reduced production of NO, the expansion factor (VEF) and may accelerate the process of atherosclerosis. The study was designed to investigate the frequency of T-786C polymorphism of the gene or nucleotide mutation of eNOS gene in patients ...

  6. Introduction of in vitro transcribed ENO1 mRNA into neuroblastoma cells induces cell death

    International Nuclear Information System (INIS)

    Ejeskär, Katarina; Krona, Cecilia; Carén, Helena; Zaibak, Faten; Li, Lingli; Martinsson, Tommy; Ioannou, Panayiotis A

    2005-01-01

    Neuroblastoma is a solid tumour of childhood often with an unfavourable outcome. One common genetic feature in aggressive tumours is 1p-deletion. The α-enolase (ENO1) gene is located in chromosome region 1p36.2, within the common region of deletion in neuroblastoma. One alternative translated product of the ENO1 gene, known as MBP-1, acts as a negative regulator of the c-myc oncogene, making the ENO1 gene a candidate as a tumour suppressor gene. Methods used in this study are transfection of cDNA-vectors and in vitro transcribed mRNA, cell growth assay, TUNEL-assay, real-time RT-PCR (TaqMan) for expression studies, genomic sequencing and DHPLC for mutation detection. Here we demonstrate that transfection of ENO1 cDNA into 1p-deleted neuroblastoma cell lines causes' reduced number of viable cells over time compared to a negative control and that it induces apoptosis. Interestingly, a similar but much stronger dose-dependent reduction of cell growth was observed by transfection of in vitro transcribed ENO1 mRNA into neuroblastoma cells. These effects could also be shown in non-neuroblastoma cells (293-cells), indicating ENO1 to have general tumour suppressor activity. Expression of ENO1 is detectable in primary neuroblastomas of all different stages and no difference in the level of expression can be detected between 1p-deleted and 1p-intact tumour samples. Although small numbers (11 primary neuroblastomas), there is some evidence that Stage 4 tumours has a lower level of ENO1-mRNA than Stage 2 tumours (p = 0.01). However, mutation screening of 44 primary neuroblastomas of all different stages, failed to detect any mutations. Our studies indicate that ENO1 has tumour suppressor activity and that high level of ENO1 expression has growth inhibitory effects

  7. Effects of Training Programme on HIV/AIDS Prevention among Primary Health Care Workers in Oyo State, Nigeria

    Science.gov (United States)

    Ajuwon, Ademola; Funmilayo, Fawole; Oladepo, Oladimeji; Osungbade, Kayode; Asuzu, Michael

    2008-01-01

    Purpose: The purpose of this paper is to train primary health care workers to be trainers and implementers of community-based AIDS prevention activities in Oyo State, Nigeria, by describing an evaluation of the project. Design/methodology/approach: A total of 148 primary health care workers recruited from the 33 local government areas (LGA) of the…

  8. Awareness of Climate Change and Sustainable Development among Undergraduates from Two Selected Universities in Oyo State, Nigeria

    Science.gov (United States)

    Agboola, Omowunmi Sola; Emmanuel, Michael

    2016-01-01

    This study investigated awareness of climate change and sustainable development among undergraduates in two universities: University of Ibadan, Ibadan and Ladoke Akintola University of Technology, Ogbomoso in Oyo State of Nigeria. This was aimed at increasing the knowledge of undergraduates on climate change and sustainable development. The study…

  9. Tested, Trusted, Yet Frustrating: An Investigation into the Effectiveness of Environmental Radio Jingles in Oyo State Nigeria

    Science.gov (United States)

    Ojebode, Ayo

    2005-01-01

    Radio stations have used jingles for environmental education and communication in Nigeria for decades though not much has been done to study the impact of such use--which is the purpose of this article. Through 12 focus group discussions (FGDs) in six local government areas of Oyo state, Nigeria, interviews with the program directors of two radio…

  10. Principals' Human Capital Development Practices for Enhancing Staff Personnel Administration in Secondary Schools in Oyo State, Nigeria

    Science.gov (United States)

    Chidi, Nnebedum; Victor, Akinfolarin Akinwale

    2017-01-01

    Unsatisfactory performance of secondary school students in external examinations in Oyo State seems to suggest lapses in principals' application of human capital development practices especially in the areas of training and mentoring of teachers to enhance instructional delivery. This unpleasant state of affair necessitated the researchers to…

  11. Activities and influence of veterinary drug marketers on antimicrobial usage in livestock production in Oyo and Kaduna States, Nigeria

    OpenAIRE

    Olufemi Ernest Ojo; Olajoju Jokotola Awoyomi; Eniola Fabusoro; Morenike Atinuke Dipeolu

    2017-01-01

    Antimicrobial usage in animals contributes to the emergence of antimicrobial resistant bacterial strains. Investigations were carried out on how the characteristics, knowledge, attitude and practices of antimicrobial marketers influenced antimicrobials usage in animal production in Oyo and Kaduna States, Nigeria. Focus group discussions, in-depth interviews and structured questionnaires were used to gather information about the characteristics and activities of antimicrobial marketers. Overal...

  12. A central role of eNOS in the protective effect of wine against metabolic syndrome.

    Science.gov (United States)

    Leighton, Federico; Miranda-Rottmann, Soledad; Urquiaga, Inés

    2006-01-01

    The positive health effects derived from moderate wine consumption are pleiotropic. They appear as improvements in cardiovascular risk factors such as plasma lipids, haemostatic mechanisms, endothelial function and antioxidant defences. The active principles would be ethanol and mainly polyphenols. Results from our and other laboratories support the unifying hypothesis that the improvements in risk factors after red wine consumption are mediated by endothelial nitric oxide synthase (eNOS). Many genes are involved, but the participation of eNOS would be a constant feature. The metabolic syndrome is a cluster of metabolic risk factors associated with high risk of cardiovascular disease (CVD). The National Cholesterol Education Programmmes Adult Treatment Panel III (NCEPATP III) clinical definition of the metabolic syndrome requires the presence of at least three risk factors, from among abdominal obesity, high plasma triacylglycerols, low plasma HDL, high blood pressure and high fasting plasma glucose. The molecular mechanisms responsible for the metabolic syndrome are not known. Since metabolic syndrome apparently affects 10-30% of the population in the world, research on its pathogenesis and control is needed. The recent finding that eNOS knockout mice present a cluster of cardiovascular risk factors comparable to those of the metabolic syndrome suggests that defects in eNOS function may cause human metabolic syndrome. These mice are hypertensive, insulin resistant and dyslipidemic. Further support for a pathogenic role of eNOS comes from the finding in humans that eNOS polymorphisms associate with insulin resistance and diabetes, with hypertension, with inflammatory and oxidative stress markers and with albuminuria. So, the data sustain the hypothesis that eNOS enhancement should reduce metabolic syndrome incidence and its consequences. Therefore red wine, since it enhances eNOS function, should be considered as a potential tool for the control of metabolic

  13. Circulating Blood eNOS Contributes to the Regulation of Systemic Blood Pressure and Nitrite Homeostasis

    Science.gov (United States)

    Wood, Katherine C.; Cortese-Krott, Miriam M.; Kovacic, Jason C.; Noguchi, Audrey; Liu, Virginia B.; Wang, Xunde; Raghavachari, Nalini; Boehm, Manfred; Kato, Gregory J.; Kelm, Malte; Gladwin, Mark T.

    2013-01-01

    Objective Mice genetically deficient in endothelial nitric oxide synthase (eNOS−/−) are hypertensive with lower circulating nitrite levels, indicating the importance of constitutively produced nitric oxide (NO•) to blood pressure regulation and vascular homeostasis. While the current paradigm holds that this bioactivity derives specifically from expression of eNOS in endothelium, circulating blood cells also express eNOS protein. A functional red cell eNOS that modulates vascular NO• signaling has been proposed. Approach and Results To test the hypothesis that blood cells contribute to mammalian blood pressure regulation via eNOS-dependent NO• generation, we cross-transplanted WT and eNOS−/− mice, producing chimeras competent or deficient for eNOS expression in circulating blood cells. Surprisingly, we observed a significant contribution of both endothelial and circulating blood cell eNOS to blood pressure and systemic nitrite levels, the latter being a major component of the circulating NO• reservoir. These effects were abolished by the NOS inhibitor L-NAME and repristinated by the NOS substrate L-Arginine, and were independent of platelet or leukocyte depletion. Mouse erythrocytes were also found to carry an eNOS protein and convert 14C-Arginine into 14C-Citrulline in a NOS-dependent fashion. Conclusions These are the first studies to definitively establish a role for a blood borne eNOS, using cross transplant chimera models, that contributes to the regulation of blood pressure and nitrite homeostasis. This work provides evidence suggesting that erythrocyte eNOS may mediate this effect. PMID:23702660

  14. Activation of Endothelial Nitric Oxide (eNOS Occurs through Different Membrane Domains in Endothelial Cells.

    Directory of Open Access Journals (Sweden)

    Jason Tran

    Full Text Available Endothelial cells respond to a large range of stimuli including circulating lipoproteins, growth factors and changes in haemodynamic mechanical forces to regulate the activity of endothelial nitric oxide synthase (eNOS and maintain blood pressure. While many signalling pathways have been mapped, the identities of membrane domains through which these signals are transmitted are less well characterized. Here, we manipulated bovine aortic endothelial cells (BAEC with cholesterol and the oxysterol 7-ketocholesterol (7KC. Using a range of microscopy techniques including confocal, 2-photon, super-resolution and electron microscopy, we found that sterol enrichment had differential effects on eNOS and caveolin-1 (Cav1 colocalisation, membrane order of the plasma membrane, caveolae numbers and Cav1 clustering. We found a correlation between cholesterol-induced condensation of the plasma membrane and enhanced high density lipoprotein (HDL-induced eNOS activity and phosphorylation suggesting that cholesterol domains, but not individual caveolae, mediate HDL stimulation of eNOS. Vascular endothelial growth factor (VEGF-induced and shear stress-induced eNOS activity was relatively independent of membrane order and may be predominantly controlled by the number of caveolae on the cell surface. Taken together, our data suggest that signals that activate and phosphorylate eNOS are transmitted through distinct membrane domains in endothelial cells.

  15. Librarian-initiated HIV/AIDS prevention intervention program outcome in rural communities in Oyo State, Nigeria.

    Science.gov (United States)

    Ajuwon, G A; Komolafe-Opadeji, H O; Ikhizama, B

    2013-01-01

    The objective of this study was to meet the HIV/AIDS information and service needs of citizens living in selected rural, underserved communities in Oyo State, Nigeria. This was a librarian-initiated intervention program (pre-post) study of heads of rural households in Oyo State. A questionnaire was used for pre- and post-intervention assessment. The education covered knowledge about HIV/AIDS, routes of transmission, prevention strategies, and attitude toward persons living with HIV. It increased participants' knowledge about AIDS and improved attitude toward those living with HIV. Provision and dissemination of information on HIV/AIDS through librarians to rural settlers is an important prevention strategy and librarians can make major contributions.

  16. Mild mitochondrial uncoupling and calorie restriction increase fasting eNOS, akt and mitochondrial biogenesis.

    Science.gov (United States)

    Cerqueira, Fernanda M; Laurindo, Francisco R M; Kowaltowski, Alicia J

    2011-03-31

    Enhanced mitochondrial biogenesis promoted by eNOS activation is believed to play a central role in the beneficial effects of calorie restriction (CR). Since treatment of mice with dinitrophenol (DNP) promotes health and lifespan benefits similar to those observed in CR, we hypothesized that it could also impact biogenesis. We found that DNP and CR increase citrate synthase activity, PGC-1α, cytochrome c oxidase and mitofusin-2 expression, as well as fasting plasma levels of NO• products. In addition, eNOS and Akt phosphorylation in skeletal muscle and visceral adipose tissue was activated in fasting CR and DNP animals. Overall, our results indicate that systemic mild uncoupling activates eNOS and Akt-dependent pathways leading to mitochondrial biogenesis.

  17. Mild mitochondrial uncoupling and calorie restriction increase fasting eNOS, akt and mitochondrial biogenesis.

    Directory of Open Access Journals (Sweden)

    Fernanda M Cerqueira

    2011-03-01

    Full Text Available Enhanced mitochondrial biogenesis promoted by eNOS activation is believed to play a central role in the beneficial effects of calorie restriction (CR. Since treatment of mice with dinitrophenol (DNP promotes health and lifespan benefits similar to those observed in CR, we hypothesized that it could also impact biogenesis. We found that DNP and CR increase citrate synthase activity, PGC-1α, cytochrome c oxidase and mitofusin-2 expression, as well as fasting plasma levels of NO• products. In addition, eNOS and Akt phosphorylation in skeletal muscle and visceral adipose tissue was activated in fasting CR and DNP animals. Overall, our results indicate that systemic mild uncoupling activates eNOS and Akt-dependent pathways leading to mitochondrial biogenesis.

  18. Tidal breath eNO measurements in a cohort of unsedated hospitalized neonates-A method validation

    DEFF Research Database (Denmark)

    Schmidt, Birgitte J; Reim, Pauline S; Jensen, Andreas K

    2018-01-01

    to validate clinically feasible longitudinal online tidal eNO and V'NO in a real-life birth cohort of un-sedated, hospitalized preterm, and term neonates. METHOD: We included 149 newborns, GA 28-42 weeks. Each scheduled for six repeated, non-invasive, on-line eNO measurements with Ecomedics CLD 88sp and NO...

  19. Stability analysis and it prime s application of a guided vehicle with target tracker model uncertainties. Mokuhyo tsuibi sochi no model fukakuteisei wo koryo ni ireta hishotai yudo seigyokei no antei kaiseki to sono oyo

    Energy Technology Data Exchange (ETDEWEB)

    Eguchi, H; Tanaka, T [Defence Agency, Tokyo (Japan); Yamashita, T [Kyushu Inst. of Technology, Fukuoka (Japan)

    1990-08-05

    The stability of a missile guidance system was analyzed with the Popov {prime} s hyperstability theory, considering target tracker model uncertainties. After the basic block diagram was derived as a mathematical model of the guidance system, the stability of the guidance system was analyzed as a nonlinear time-variable system, based on the Popov {prime} s hyperstability theory. Based on the results, several requirements of target tracker model uncertainties, and dynamic properties such as a natural frequency and damping characteristics of missiles, were derived for the hyperstability of the guidance system. In addition, after the hyperstable minimum range of missiles was defined, the relation was given by the use of an example between target tracker model uncertainties and the hyperstable minimum range or miss distance. As a result, the analysis allowed to derive design requirements such as dynamic properties for robust guidance systems. 12 refs., 11 figs., 2 tabs.

  20. Orthodontic force stimulates eNOS and iNOS in rat osteocytes

    NARCIS (Netherlands)

    Tan, S.D.; Xie, R.; Klein Nulend, J.; van Rheden, R.E.; Bronckers, A.L.J.J.; Kuijpers-Jagtman, A.M.; Von den Hoff, J.W.; Maltha, J.C.

    2009-01-01

    Mechanosensitive osteocytes are essential for bone remodeling. Nitric oxide, an important regulator of bone remodeling, is produced by osteocytes through the activity of constitutive endothelial nitric oxide synthase (eNOS) or inducible nitric oxide synthase (iNOS). We hypothesized that these

  1. Orthodontic force stimulates eNOS and iNOS in rat osteocytes.

    NARCIS (Netherlands)

    Tan, S.D.; Xie, R.; Klein-Nulend, J.; Rheden, R.E.M. van; Bronckers, A.L.; Kuijpers-Jagtman, A.M.; Hoff, J.W. Von den; Maltha, J.C.

    2009-01-01

    Mechanosensitive osteocytes are essential for bone remodeling. Nitric oxide, an important regulator of bone remodeling, is produced by osteocytes through the activity of constitutive endothelial nitric oxide synthase (eNOS) or inducible nitric oxide synthase (iNOS). We hypothesized that these

  2. Association between nucleotide mutation of eNOS gene and serum ...

    African Journals Online (AJOL)

    Galaxy

    2013-05-15

    May 15, 2013 ... spasm among Japanese (Nakayama et al., 1999; Casas et al., 2006). It is believed that these mutations might result in altered NO metabolism and impaired .... ship between T-786C mutation of eNOS gene and CAD specifically in the Iranian population. To our knowledge, this polymorphism has never been ...

  3. Association of eNOS and HSP70 gene polymorphisms with glaucoma in Pakistani cohorts.

    NARCIS (Netherlands)

    Ayub, H.; Khan, M.I.; Micheal, S.; Akhtar, F.; Ajmal, M.; Shafique, S.; Ali, S.H.; Hollander, A.I. den; Ahmed, A.; Qamar, R.

    2010-01-01

    PURPOSE: To investigate the involvement of stress-regulating genes, endothelial nitric oxide synthase (eNOS) and heat shock protein 70 (HSP70) with primary open angle glaucoma (POAG) and primary closed angle glaucoma (PCAG). METHODS: POAG and PCAG patients recruited from different areas of Pakistan

  4. A meta-analysis of eNOS and ACE gene polymorphisms and risk of pre-eclampsia in women.

    Science.gov (United States)

    Shaik, A P; Sultana, A; Bammidi, V K; Sampathirao, K; Jamil, K

    2011-10-01

    A meta-analyses of endothelial nitric oxide synthase (eNOS) and angiotensin-converting enzyme (ACE) gene polymorphisms in pre-eclampsia was performed. We shortlisted 33 studies (17 for ACE; 16 for eNOS gene polymorphisms), of which 29 articles (16 for ACE and 15 for eNOS) were analysed. Overall, 1,620 cases with pre-eclampsia and 2,158 controls were analysed for intron 16 insertion-deletion polymorphism in ACE gene. A total of 1,610 subjects with pre-eclampsia and 2,875 controls were analysed for the Glu298Asp in eNOS gene. Overall, the random-effects odds ratio (OR) with Glu298Asp in eNOS gene was 0.958 (95% confidence intervals, CI 0.747-1.228, p > 0.05), and for the insertion-deletion/ACE polymorphism was 0.987 (95% CI 0.698-1.395, p > 0.05). Significant heterogeneity was observed in the studies that evaluated polymorphisms in ACE (Q value = 55.6; I(2) = 73; p value = 0.000); and eNOS (Q value = 37.2; I(2) = 62.4; p value = 0.001) polymorphisms. No significant risk of pre-eclampsia was observed in both eNOS and ACE genes with these polymorphisms.

  5. Gender, exercise training, and eNOS expression in porcine skeletal muscle arteries.

    Science.gov (United States)

    Laughlin, M Harold; Welshons, Wade V; Sturek, Michael; Rush, James W E; Turk, James R; Taylor, Julia A; Judy, Barbara M; Henderson, Kyle K; Ganjam, V K

    2003-07-01

    Our purpose was to determine the effects of gender and exercise training on endothelial nitric oxide synthase (eNOS) and superoxide dismutase (SOD) protein content of porcine skeletal muscle arteries and to evaluate the role of 17beta-estradiol (E2) in these effects. We measured eNOS and SOD content with immunoblots and immunohistochemistry in femoral and brachial arteries of trained and sedentary male and female pigs and measured estrogen receptor (ER) mRNA and alpha-ER and beta-ER protein in aortas of male and female pigs. Results indicate that female arteries contain more eNOS than male arteries and that exercise training increases eNOS content independent of gender. Male and female pigs expressed similar levels of alpha-ER mRNA and protein and similar amounts beta-ER protein in their arteries. E2 concentrations as measured by RIA were 180 +/- 34 pg/ml in male sera and approximately 5 pg/ml in female sera, and neither was changed by training. However, bioassay indicated that biologically active estrogen equivalent to only 35 +/- 5 pg/ml was present in male sera. E2 in female pigs, whether measured by RIA or bioassay, was approximately 24 pg/ml at peak estrous and 2 pg/ml on day 5 diestrus. The free fraction of E2 in sera did not explain the low measurements, relative to RIA, of E2. We conclude that 1). gender has significant influence on eNOS and SOD content of porcine skeletal muscle arteries; 2). the effects of gender and exercise training vary among arteries of different anatomic origin; 3). male sera contains compounds that cause RIA to overestimate circulating estrogenic activity; and 4). relative to human men, the male pig is not biologically estrogenized by high levels of E2 reported by RIA, whereas in female pigs E2 levels are lower than in the blood of human women.

  6. Effect of rural transportation system on agricultural productivity in Oyo State, Nigeria

    Directory of Open Access Journals (Sweden)

    Ezekiel Olukayode Idowu

    2012-04-01

    Full Text Available Food farming in Oyo North, Nigeria is characterised by an increasing use of Intermediary Mode of Transportation (IMT to ease inputs and outputs mobility and farm access. To assess the influence on food farmer’s productivity, a random sample of 230 respondents was selected and data collected on their socio-economic and farm specific characteristics. Descriptive statistics, Herfindhal Index and Technical Efficiency Approach were used to analyse the data. The results indicate that majority of food farmers were in their middle age with mean age of 50 years and most of them used one plot at a location between 5 and 10km to their village of residence. They acquired land by inheritance and practiced intensive crop diversification as risk management strategy. The transportation modes used in addition to walking include bicycle, motorcycle, and car with increasing trend in the use of motorcycle. The mean Technical Efficiency (TE of food farmers was 0.82 with significant inefficiency effects. The inefficiency analysis indicates positive effect of distance, crop diversification and un-tarred type of road on farmer’s productivity, while poor level of education among farmers, use of bicycle; trekking and weekly working time negatively affect farmer’s efficiency. The negative effect of trekking and use of bicycle and the excess working time suggest the adoption of more IMT of motorized type to optimize farming time and increase farmer’s productivity.

  7. KAJIAN GEOMORFOLOGI UNTUK PERENCANAAN PENGGUNAAN LAHAN DI DAERAH ALIRAN SUNGAI OYO, GUNUNGKIDUL, DAERAH ISTIMEWA YOGYAKARTA

    Directory of Open Access Journals (Sweden)

    Karmono Mangunsukardjo

    2016-10-01

    Full Text Available ABSTRAK Penelitian ini bertujuan untuk mengetahui peranan geomorfologi dalam perencanaan penggunaan lahan di Daerah Aliran Sungai Oyo, Gunungkidul, Daerah Istimewa Yogyakarta. Arahan perencanaan penggunaan lahan didasarkan pada kelas kemampuan lahan dengan satuan medan sebagai satuan evaluasi dan acuan petanya. Satuan medan yang disusun atas satuan bentuklahan, lereng, dan tanah, sedangkan untuk penentuan kelas kemampuan lahannya ditambang dengan factor batu di permukaan, airtanah, dan genangan. Evaluasi kemampuan lahan dilakukan dengan cara matching antara karakteristik lahan dalam setiap satuan medan terhadap persyaratan kelas kemampuan lahan dengan menggunakan system informasi geografis (SIG. Hasil penelitian menunjukkan bahwa satuan medan yang disusun berdasarkan kerangka dasar geomorfologi mampu memberikan penilaian kemampuan lahan dan arahan penggunaan lahan. Satuan medan pegunungan structural-denudasional (SP, perbukitan structural-denudasional (SB, mempunyai kelas kemampuan lahan VI, sehingga tidak boleh dimanfaatkan dan seharusnya dijadikan lahan konservasi. Satuan medan lain yang mempunyai kelas kemampuan lahan IV seperti SBk, KD, KDt dapat dimanfaatkan untuk pertanian sangat terbatas. Satuan medan yang berkelas kemampuan lahan III adalah FT, SI, KDa, dan KLb yang memungkinkan untuk lahan pertanian terbatas. Erosi dan sifat tanah merupakan faktor kendala lahan pertanian pada satuan medan dengan kelas kemampuan lahan III.

  8. Socio-economic impacts of charcoal production in Oke-Ogun area of Oyo State, Nigeria

    Directory of Open Access Journals (Sweden)

    Olasimbo Olarinde

    2018-04-01

    Full Text Available Many households in developing countries experience low energy consumption and this make them depend upon wood fuels for their energy. This study examined socio-economic impacts of charcoal production in Oke-Ogun, Oyo State, Nigeria. Two Local Government Areas were selected based on the accessibility and the availability of charcoal farmers among ten Local Government Areas. Results show that 74% of the respondents were male while 26% were female that are into production of charcoal in the study area. 37.5% of the age range (41–50 of respondent produces more charcoal than other age range. The respondent did not go beyond primary school educationally and they are all married. However, respondents with over 11–20 years of experience in the production of charcoal have higher percentage of frequency. Some of the problem faced by the producers of charcoal in Oke Ogun area are scarcity of trees, wildfire, government disturbance and transportation. Trees commonly used for production are from inherited farms and most of the trees used are Butyrosopermum paradoxium, Dialium guineense, Terminalia glaucencens, Khaya ivorensis. Production is once in a month and later exported. Energy provision is a basic human need and consumption is closely related to the level of a country’s development.

  9. Determinants of Food Security Status of Maize-Based Farming Households in Southern Guinea Savannah Area of Oyo State, Nigeria.

    Directory of Open Access Journals (Sweden)

    Oluwayemisi Abidemi Onasanya

    2016-05-01

    Full Text Available Nigeria is one of the countries in sub-Saharan Africa with insufficient food and high food import bill, which have debilitating effects on the productive capacity of the citizens. Maize is the most important cereal after rice and its production contributes immensely to food availability on the tables of many Nigerians. This study examined the contribution of maize production to household food security status of rural maize-farming households in the southern guinea savannah of Oyo state, Nigeria. A multistage sampling procedure was used to select 200 farm households and the data were analysed using descriptive statistics, recommended daily calorie requirement (RDCR approach, Logit model. Results showed that about three-quarters of the households were food secure and were able to meet the recommended calorie intake of 2260Kcal per capita per day. The shortfall index (P which measures the extent of deviation from the food security line, indicated that the food secure households exceeded the RDCR by 65%, while the food insecure households fell short of the RDCR by 31%. The logit model showed that maize output, gender, primary occupation of the farmer, farm size and farming experience had a positive influence on food security status while age had a negative influence on the food security status of maize-based farming households in the Southern Guinea Savannah of Oyo State, Nigeria. This suggests need for specific support to improve maize production

  10. National Health Insurance Scheme: How Protected Are Households in Oyo State, Nigeria from Catastrophic Health Expenditure?

    Directory of Open Access Journals (Sweden)

    Olayinka Stephen Ilesanmi

    2014-05-01

    Full Text Available Background The major objective of the National Health Insurance Scheme (NHIS in Nigeria is to protect families from the financial hardship of large medical bills. Catastrophic Health Expenditure (CHE is rampart in Nigeria despite the take-off of the NHIS. This study aimed to determine if households enrolled in the NHIS were protected from having CHE. Methods The study took place among 714 households in urban communities of Oyo State. CHE was measured using a threshold of 40% of monthly non-food expenditure. Descriptive statistics were done, Principal Component Analysis was used to divide households into wealth quintiles. Chi-square test and binary logistic regression were done. Results The mean age of household respondent was 33.5 years. The median household income was 43,500 naira (290 US dollars and the range was 7,000–680,000 naira (46.7–4,533 US dollars in 2012. The overall median household healthcare cost was 890 naira (5.9 US dollars and the range was 10-17,700 naira (0.1–118 US dollars in 2012. In all, 67 (9.4% households were enrolled in NHIS scheme. Healthcare services was utilized by 637 (82.9% and CHE occurred in 42 (6.6% households. CHE occurred in 14 (10.9% of the households in the lowest quintile compared to 3 (2.5% in the highest wealth quintile (P= 0.004. The odds of CHE among households in lowest wealth quintile is about 5 times. They had Crude OR (CI: 4.7 (1.3–16.8, P= 0.022. Non enrolled households were two times likely to have CHE, though not significant Conclusion Households in the lowest wealth quintiles were at higher risk of CHE. Universal coverage of health insurance in Nigeria should be fast-tracked to give the expected financial risk protection and decreased incidence of CHE.

  11. Activation of eNOS in endothelial cells exposed to ionizing radiation involves components of the DNA damage response pathway

    Energy Technology Data Exchange (ETDEWEB)

    Nagane, Masaki; Yasui, Hironobu; Sakai, Yuri; Yamamori, Tohru [Laboratory of Radiation Biology, Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060-0818 (Japan); Niwa, Koichi [Laboratory of Biochemistry, Department of Food and Cosmetic Science, Faculty of Bioindustry, Tokyo University of Agriculture, Abashiri 099-2493 (Japan); Hattori, Yuichi [Department of Molecular and Medical Pharmacology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama 930-0194 (Japan); Kondo, Takashi [Department of Radiological Sciences, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama 930-0194 (Japan); Inanami, Osamu, E-mail: inanami@vetmed.hokudai.ac.jp [Laboratory of Radiation Biology, Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060-0818 (Japan)

    2015-01-02

    Highlights: • eNOS activity is increased in BAECs exposed to X-rays. • ATM is involved in this increased eNOS activity. • HSP90 modulates the radiation-induced activation of ATM and eNOS. - Abstract: In this study, the involvement of ataxia telangiectasia mutated (ATM) kinase and heat shock protein 90 (HSP90) in endothelial nitric oxide synthase (eNOS) activation was investigated in X-irradiated bovine aortic endothelial cells. The activity of nitric oxide synthase (NOS) and the phosphorylation of serine 1179 of eNOS (eNOS-Ser1179) were significantly increased in irradiated cells. The radiation-induced increases in NOS activity and eNOS-Ser1179 phosphorylation levels were significantly reduced by treatment with either an ATM inhibitor (Ku-60019) or an HSP90 inhibitor (geldanamycin). Geldanamycin was furthermore found to suppress the radiation-induced phosphorylation of ATM-Ser1181. Our results indicate that the radiation-induced eNOS activation in bovine aortic endothelial cells is regulated by ATM and HSP90.

  12. Towards unification of the Vorticity Confinement and Shock Capturing (TVD and ENO/WENO) methods

    Science.gov (United States)

    Sidilkover, David

    2018-04-01

    New multidimensional extensions of the TVD and finite difference ENO/WENO methods for the compressible flow equations are proposed. The novelty of the approach is in the discretization schemes that acquire by means of a single mechanism both shock-capturing and vorticity confinement capabilities. Thus, the new method can be interpreted as a unification of the two methodologies, intended initially for different purposes.

  13. Morus alba extract modulates blood pressure homeostasis through eNOS signaling.

    Science.gov (United States)

    Carrizzo, Albino; Ambrosio, Mariateresa; Damato, Antonio; Madonna, Michele; Storto, Marianna; Capocci, Luca; Campiglia, Pietro; Sommella, Eduardo; Trimarco, Valentina; Rozza, Francesco; Izzo, Raffaele; Puca, Annibale A; Vecchione, Carmine

    2016-10-01

    Morus alba is a promising phytomedicine cultivated in oriental countries that is extensively used to prevent and treat various cardiovascular problems. To date, despite its beneficial effects, the molecular mechanisms involved remain unclear. Thus, we investigate the vascular and haemodynamic effects of Morus alba extract in an experimental model focusing our attention on the molecular mechanisms involved. Through vascular reactivity studies, we demonstrate that Morus alba extract evokes endothelial vasorelaxation through a nitric oxide-dependent pathway. Our molecular analysis highlights an increase in endothelial nitric oxide synthase (eNOS) phosphorylation. In vivo administration of Morus alba extract reduces blood pressure levels exclusively in wild-type mice, whereas it fails to evoke any haemodynamic effects in eNOS-deficient mice. Molecular analyses revealed that its beneficial action on vasculature is mediated by the activation of two important proteins that act as stress sensors and chaperones: PERK and heat shock protein 90. Finally, Morus alba extract exerts antihypertensive action in an experimental model of arterial hypertension. Through its action on eNOS signaling, Morus alba extract could act as a food supplement for the regulation of cardiovascular system, mainly in clinical conditions characterized by eNOS dysfunction, such as arterial hypertension. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. FY 1998 report on the results of R and D projects by local consortiums for immediate effects. Development of woody ceramics and application to building parts; 1998 nendo woody ceramics no sosei to kenchiku buzai nado eno oyo seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    The R and D project has been implemented for developing materials for, e.g., light, highly heat-insulating and energy-saving type building parts (e.g., roofing tiles and tiles), and light tableware having warmness of wood. The stock materials for china and porcelain, roofing tile clay, tiles and cement are dispersed with hollow microcapsules as the filler, which are of glassy balloons thermally treated to be highly functional, in order to develop superlight, highly heat insulating and high-strength materials. For development of the woody ceramic materials, the microcapsules are investigated for size, thickness, thermal shrinkage, fusibility, compressive stress, reinforcing mechanisms, and monodispersibility. Also investigated are optimization of material formability, development of commercial ceramics and evaluation of their marketability, decoration techniques, antimicrobial membrane materials and their immobilization techniques, development of antimicrobial ceramic tiles, evaluation of the antimicrobial membranes, evaluation of resistance to microwaves, and so on. The efforts are also directed to researches on fundamental techniques for woody tile clay, and R and D of the application techniques and products of the woody cement. (NEDO)

  15. Research of the elastic waves generated by a pulse laser. Excitation mechanism of elastic waves and application to nondestructive testing; Pulse laser de reikishita danseiha ni kansuru kenkyu. Danseiha reiki no mechanism to hihakai kensa eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Cho, H.; Takemoto, M. [Aoyama Gakuin University, Tokyo (Japan). College of Science and Engineering

    1994-07-20

    A bulk wave is generated when a pulse laser is irradiated to the material, and the characteristics of a Young`s modulus and Poisson`s ratio can be nondestructively estimated from the bulk wave. The generation mechanism of laser ultrasonic waves must be first clarified for such application. In this paper, fundamental research was conducted to study the generation mechanism of the elastic waves excited by a Q-switched Nd-YAG laser, and the generation method and characteristics of Rayleigh waves. The following result was obtained. A bulk wave is generated by the disk-like adiabatic expansion near the surface if the laser power is small when a spot-shape pulse laser was irradiated. A bulk wave is generated by the thin disk-like adiabatic expansion beneath the surface due to the thermal diffusion in the depth direction of a base material when the laser power becomes large. Moreover, a bulk wave is generated by the impact force due to abrasion and plasma when the power becomes still larger. The information on the bulk wave characteristics and Rayleigh wave was also obtained. 25 refs., 15 figs., 1 tab.

  16. Report on the survey in fiscal 1998. Systematic arrangement of environment technologies. 5 (Application of advanced technologies to environmental measures); 1998 nendo chosa hokokusho. Kankyo gijutsu ni kansuru taikeiteki seiri. 5 (sentan gijutsu no kankyo taisaku eno oyo)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    Global environment handling technologies were investigated and put into order. Universities often make research and development on themes that can be handled at laboratory levels or by simulations. Development at a practical application level is few. Technological seeds may include manufacture of hydrogen by water and steam decomposition using solar energy, and new synthesizing reactions utilizing solar energy. Included may also be urban type wind power generation, superconductive energy storage systems, biomass utilization, and natural energy utilization. Furthermore, CO2 recovery and utilization by liquefaction, alkaline metal heat power generation, and pulse power technologies can also be found. Studies on applying advanced technologies to environmental measures include composite materials, membrane separation, photo-catalysts, optical elements, porous bodies, functional polymers, bio-reactors, electron beams, and aeration. Private corporations are working noticeably on prevention of fluorocarbon and dioxin emission, PCB treatment and waste water treatment technologies, catalyst application technologies, recycling technologies, and incineration ash treatment and utilization technologies. (NEDO)

  17. Study of combustion in microgravity environments and application of the findings to combustors for industrial use; Bisho juryoku kankyoka ni okeru nensho kenkyu oyobi sangyoyo nensho kiki eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Sato, J. [Ishikawajima-Harima Heavy Industries Co. Ltd., Tokyo (Japan)

    1997-09-10

    Natural convection is one of the factors that make the elucidation of the combustion phenomenon difficult. Such being the case, it is necessary to utilize microgravity enviroments to learn fuel combustion characteristics and parameters governing the combustion phenomenon for the development of optimal burning appliances. The free-fall facility of JAMIC (Japan Micro Gravity Center) creates a microgravity field that lasts for 10 seconds, and helps perform various combustion-related researches. This report outlines the findings obtained thanks to the use of this facility. In a `study concerning the creation of sophisticated combustion technology,` the combustion of 50{mu}m fuel droplets (too small to involve natural convetion) in a jet engine combustor is simulated in a microgravity field using experimentally producible 1mm drops, and the relationship between the droplet burn time and pressure is disclosed. In addition, using a small combustion furnace, the behavior of a natural-size flame is estimated and the propagation speed of a carbon powder flame is studied. 6 figs.

  18. Electrolyte loss mechanism of molten carbonate fuel cells. 2.; Application to the cell with matrix electrolyte layer; Yoyu tansan`engata nenryo denchi ni okeru denkaishitsu loss kiko ni tsuite. 2.; Matrix gata denkaishitsuso wo yusuru denchi eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Sonai, A; Murata, K [Toshiba Research and Development Center, Kawasaki (Japan)

    1993-11-01

    A single cell of molten carbonate fuel cell using a matrix electrolyte layer fabricated by using the doctor blade process has been operated for several thousand hours, measured of electrolyte loss amount, and analyzed by using a new electrolyte loss mechanism. The result may be summarized as follows: according to a result of measuring the matrix layer pore distribution, the average pore size has increased little by little; pores with diameters greater than 2 {mu}m at which no electrolyte retention becomes possible remain at nearly constant ratio up to 1800 hours, but increased after 2500 hours; the pore capacity in ports with the largest electrolyte retaining diameter of 2 {mu}m or less showed slight decrease with time in the anode, and an initial decrease followed by flatness, and then a sharp decrease after 1800 hours in the matrix layer; the electrolyte loss measurement values have remained nearly constant for 25 hours to 1800 hours, but increased sharply thereafter; and the electrolyte loss in this single cell due to pore capacity decrease in pores as power generating parts with diameters smaller than 2 {mu}m was explained quantitatively by a new electrolyte loss mechanism. 11 refs., 6 figs.

  19. FY1995 study of ultra high resolution laser and microwave spectroscopy and its application to future standards; 1995 nendo choseimitsu laser micro ha bunko to sono jisedai hyojun eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    Ultra high resolution spectroscopy is carried out in a range from microwave to ultraviolet using lasers with laser cooling, saturated absorption, 2 photon absorption and ion trap, and optical parametric oscillation is studied for optical frequency measurement. A temperature of 10 {mu}K and that of 150 mK were obtained for Cs atoms and a single Yb ion, respectively. A stability of 3.3 x 10{sup -12} was obtained for iodine stabilized YAG lasers. A saturation signal of C{sub 2}H{sub 2} was observed during wore than 9 months. An optical parametric oscillator, which was fabricated to measure an optical frequency, was probed to work continuously more than 3 hours. (NEDO)

  20. Development II of ion current combustion control system. Application to the lean burn system of the micro vehicle engine; Ion denryu wo mochiita nensho seigyo system no kaihatsu. 2. Keijidosha engine wo mochiita lean burn eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Iida, T; Asano, M; Kajitani, M; Kuma, t; Morinaga, Y [Daihatsu Motor Co. Ltd., Osaka (Japan)

    1997-10-01

    The lean bum engine has not been introduced into the micro vehicle so far because of the low cost requirement and small displacement, in spite of it is one of the effective solutions which increase the fuel economy. By the way, we had already reported in the former paper that we developed the ion current combustion control system the architecture of which is cheaper than the other system. In this paper, we described the way how the above system is applied to the lean burn system of the micro vehicle engine and also we reported the gain of fuel economy and the exhaust emission level. 5 refs., 11 figs., 2 tabs.

  1. Strain measurement of wheel by a super-small size strain history recorder and its application to fatigue design; Chokogata jitsudo hizumi keisoku sochi ni yoru wheel no hizumi keisoku to hiro kyodo sekkei eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Murakami, Y [Kyushu University, Fukuoka (Japan); Mineki, K; Wakamatsu, K [Central Motor Wheel, Tokyo (Japan); Morita, T

    1997-10-01

    A very small strain history recorder based on the rainflow method has been developed and applied to strain measurement of car wheels under several road tests. Various strain amplitude histogram data under mountain road, city road and high-way were acquired by the recorder for various types of wheels. The data were studied from the viewpoint of random fatigue and the fatigue damages were evaluated by Miner`s rule. The results of the damage evaluation were used for the improvement of shapes of wheels. 2 refs., 6 figs., 1 tab.

  2. Advanced mineral and lithological mapping using high spectral resolution TIR data from the active CO2 remote sensing system; CO2 laser wo mochiita kosupekutoru bunkaino netsusekigai remote sensing data no ganseki kobutsu shikibetsu eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Okada, K [Sumitomo Metal Mining Co. Ltd., Osaka (Japan); Hato, M [Earth Remote Sensing Data Analysis Center, Tokyo (Japan); Cudahy, T; Tapley, I

    1997-05-27

    A study was conducted on rock/mineral mapping technology for the metal ore deposit survey using MIRACO2LAS, an active type thermal infrared ray remote sensing system which was developed by CSIRO of Australia and is now the highest in spectral resolution in the world, and TIMS of NASA which is a passive type system. The area for the survey is the area of Olary/Broken Hill and Mt. Fitton of Australia. A good correlation is seen between the ground reflectance measured by MIRACO2LAS and the value measured by the chamber CO2 laser of rocks sampled at the above-mentioned area. In case that the width of spectral characteristics is below 300nm, the inspection ability by MIRACO2LAS`s high spectral resolution is more determined in mineral mapping as compared with TIMS which is large in band width. Minerals mapped using MIRACO2LAS are quartz, talc, amphibole, hornblende, garnet, supessartine, dolomite, magnesite, etc. 4 refs., 3 figs.

  3. Sterilization using ozone-ion gas sterilization using ozone-ion gas for mattresses used by the elderly; Ozone ion kunjoho ni kansuru kenkyu. Ozone ion kunjoho no zaitaku kaigoyo mattress mekkin eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Mikami, H.; Suzuki, A.; Hamasaki, H. [Shinryo Corp., Tokyo (Japan); Ishikawa, S.; Miyata, M.; Nanba, T. [Kitasato Univ., Tokyo (Japan); Sueyoshi, K. [Mitsubishi Research Institute Inc., Tokyo (Japan)

    1999-05-25

    The new generation of Japanese is facing an aging society: the number of young people is decreasing dramatically, while the number of elderly is increasing. Consequently, care for the elderly has become a big problem. One particular problem area we`ve investigated is the use of unclean mattresses by the bedridden elderly. These mattresses provide an all too excellent environments for the growth of microbes. We measured the density of microbes on the cover of mattresses at 775cfu/cm{sup 2} and in the bed filling at 136cfu/g. The dominant species of microbes were MRSA and Bacillus. We used MRSA, Bacillus subtilis and Escherichia coli as biological indicators and tested whether our system using ozone-ion fumigants was applicable for sterilization of mattresses. The survival ratio of MRSA were 10{sup -8} {approx} 10{sup -9}, 10{sup -7} {approx} 10{sup -8} for B. subtilis and below 10{sup -8} for E. coli. These experiments made it clear that our system is applicable for sterilization of the mattresses used by bedfast elderly. (author)

  4. Evaluation report on the study on the application of 3D woven C/C composite materials; Sanjigenori C/C composite zairyo no kikai buhin eno oyo ni kansuru kenkyu hyoka hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The paper described a study made during 1995 through 1998 on the application of 3D woven C/C composite materials to machine parts. The materials are large in rigidity, small in specific gravity, excellent in specific rigidity, and suitable for high speed rotation. They are excellent in heat resistance/dynamic reformation and expected as materials which can exceed limits of the existing steel for machine parts. However, to use them as machine parts, a possibility of high precision cutting is required. Therefore, a study was made on metal multi-layer membrane coating to C/C composites. Pitch-system high-elastic carbon fibers were made a 4-directional material by orienting horizontally in 3 directions at 120 degrees per plane and also orienting vertically. Various materials such as W, Mo and WC were coated by the laser assisted plasma hybrid spraying method. High adhesion coats with little pore were obtained. Multi-directionally woven C/C composites used to be poor in surface precision workability, but the problem was able to be solved by coating surfaces with metal layers and metal multi-layer membranes. The application is expanded not only to polygonal mirrors (for laser printing machine) and milling spindles, but largely to machine parts. 11 figs., 1 tab.

  5. Equivalent CTOD concept based on the local approach and its application to fracture performance evaluation of welded joints; Local approach ni motozuku toka CTOD gainen no teian to tsugite hakai seino hyoka eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Ohata, M.; Minami, F.; Toyoda, M. [Osaka University, Osaka (Japan). Faculty of Engineering; Tanaka, T.; Arimochi, K. [Sumitomo Metal Industries, Ltd., Osaka (Japan); Glover, A. [Nova Gas Transmission Ltd., Calgary (Canada); North, T. [University of Toronto (Canada)

    1996-12-31

    A proposal was given on an equivalent crack tip opening displacement (CTOD) concept which relates quantitatively fracture performance of a structural member with the result of a three-point bending CTOD test via the Weibull stress based on a local approach. The equivalent CTOD is defined as a CTOD in which a three-point CTOD test piece and a structural member provide the same Weibull stress. Experimental and analytical discussions were performed on X80 steel welded joints. Effectiveness of the equivalent CTOD concept was verified from the fact that the fracture performance in welded joints with a large width estimated from the result of the three-point bending CTOD test using the equivalent CTOD concept showed good correspondence with the fracture performance obtained in the experiments. On the other hand, the result of estimation using the conventional CTOD concept is considerably smaller than measurements. As an application of the equivalent CTOD concept, a new determination procedure was introduced on required fracture tenacity to ensure deformation performance required on structural elements. The required CTOD value shows a trend that the smaller the ratio of yield stress of the welded metals to that in the base material, the greater the required CTOD grows. 16 refs., 19 figs., 3 tabs.

  6. Development of hydriding alloys with multi-functionally-graded properties and their applications to energy conversion devices; Keishagata fukugo kino wo hyomen ni motsu suiso kyuzo gokin no kaihatsu to energy henkan gijutsu eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Suda, S; Kadoma, H; Nagamoto, H; Okura, T [Kogakuin University, Tokyo (Japan)

    1997-02-01

    This paper describes the formation of fluoride layer on the surface of hydriding alloys. The fluoride formation reaction consists of a reduction removal process of surface oxide and a fluorination process. Specific surface area of alloy grains can be increased by the hydrogenation reaction in the surface layer accompanied with the removal of surface oxide, which results in easier permeation of molecular hydrogen into fluoride layer. During the fluorination process, a large amount of Ni in the alloy components is eluted, which results in the reduction of Ni distribution immediately under the fluoride layer in the alloy. Consequently, collector sites near the surface are reduced, and conductivity among alloy grains is degraded. To enhance the hydrogen collector sites, specific surface area of alloy grains can be increased by controlling the pH value of fluorination treatment solution in a given range. Moreover, performance of fluoride layer can be advanced by electrochemically dispersing metal Ni in the fluoride layer using Ni complex ion mixed in the treatment solution. 2 refs., 3 figs.

  7. Equivalent CTOD concept based on the local approach and its application to fracture performance evaluation of welded joints; Local approach ni motozuku toka CTOD gainen no teian to tsugite hakai seino hyoka eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Ohata, M; Minami, F; Toyoda, M [Osaka University, Osaka (Japan). Faculty of Engineering; Tanaka, T; Arimochi, K [Sumitomo Metal Industries, Ltd., Osaka (Japan); Glover, A [Nova Gas Transmission Ltd., Calgary (Canada); North, T [University of Toronto (Canada)

    1997-12-31

    A proposal was given on an equivalent crack tip opening displacement (CTOD) concept which relates quantitatively fracture performance of a structural member with the result of a three-point bending CTOD test via the Weibull stress based on a local approach. The equivalent CTOD is defined as a CTOD in which a three-point CTOD test piece and a structural member provide the same Weibull stress. Experimental and analytical discussions were performed on X80 steel welded joints. Effectiveness of the equivalent CTOD concept was verified from the fact that the fracture performance in welded joints with a large width estimated from the result of the three-point bending CTOD test using the equivalent CTOD concept showed good correspondence with the fracture performance obtained in the experiments. On the other hand, the result of estimation using the conventional CTOD concept is considerably smaller than measurements. As an application of the equivalent CTOD concept, a new determination procedure was introduced on required fracture tenacity to ensure deformation performance required on structural elements. The required CTOD value shows a trend that the smaller the ratio of yield stress of the welded metals to that in the base material, the greater the required CTOD grows. 16 refs., 19 figs., 3 tabs.

  8. A novel multiplex PCR-RFLP method for simultaneous detection of the MTHFR 677 C > T, eNOS +894 G > T and - eNOS -786 T > C variants among Malaysian Malays

    Directory of Open Access Journals (Sweden)

    Loo Keat

    2012-05-01

    Full Text Available Abstract Background Hyperhomocysteinemia as a consequence of the MTHFR 677 C > T variant is associated with cardiovascular disease and stroke. Another factor that can potentially contribute to these disorders is a depleted nitric oxide level, which can be due to the presence of eNOS +894 G > T and eNOS −786 T > C variants that make an individual more susceptible to endothelial dysfunction. A number of genotyping methods have been developed to investigate these variants. However, simultaneous detection methods using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP analysis are still lacking. In this study, a novel multiplex PCR-RFLP method for the simultaneous detection of MTHFR 677 C > T and eNOS +894 G > T and eNOS −786 T > C variants was developed. A total of 114 healthy Malay subjects were recruited. The MTHFR 677 C > T and eNOS +894 G > T and eNOS −786 T > C variants were genotyped using the novel multiplex PCR-RFLP and confirmed by DNA sequencing as well as snpBLAST. Allele frequencies of MTHFR 677 C > T and eNOS +894 G > T and eNOS −786 T > C were calculated using the Hardy Weinberg equation. Methods The 114 healthy volunteers were recruited for this study, and their DNA was extracted. Primer pair was designed using Primer 3 Software version 0.4.0 and validated against the BLAST database. The primer specificity, functionality and annealing temperature were tested using uniplex PCR methods that were later combined into a single multiplex PCR. Restriction Fragment Length Polymorphism (RFLP was performed in three separate tubes followed by agarose gel electrophoresis. PCR product residual was purified and sent for DNA sequencing. Results The allele frequencies for MTHFR 677 C > T were 0.89 (C allele and 0.11 (T allele; for eNOS +894 G > T, the allele frequencies were 0.58 (G allele and 0.43 (T allele; and for eNOS −786 T > C, the allele

  9. ENO1 promotes tumor proliferation and cell adhesion mediated drug resistance (CAM-DR) in Non-Hodgkin's Lymphomas

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, Xinghua; Miao, Xiaobing; Wu, Yaxun; Li, Chunsun; Guo, Yan; Liu, Yushan; Chen, Yali; Lu, Xiaoyun [Department of Pathology, Affiliated Cancer Hospital of Nantong University, 30 North Tongyang Road, Pingchao, Nantong 226361, Jiangsu (China); Wang, Yuchan, E-mail: wangyuchannt@126.com [Department of Pathogen and Immunology, Medical College, Nantong University, 19 Qixiu Road, Nantong 226001, Jiangsu (China); He, Song, E-mail: hesongnt@126.com [Department of Pathology, Affiliated Cancer Hospital of Nantong University, 30 North Tongyang Road, Pingchao, Nantong 226361, Jiangsu (China)

    2015-07-15

    Enolases are glycolytic enzymes responsible for the ATP-generated conversion of 2-phosphoglycerate to phosphoenolpyruvate. In addition to the glycolytic function, Enolase 1 (ENO1) has been reported up-regulation in several tumor tissues. In this study, we investigated the expression and biologic function of ENO1 in Non-Hodgkin's Lymphomas (NHLs). Clinically, by western blot analysis we observed that ENO1 expression was apparently higher in diffuse large B-cell lymphoma than in the reactive lymphoid tissues. Subsequently, immunohistochemical staining of 144 NHLs suggested that the expression of ENO1 was significantly lower in the indolent lymphomas compared with the progressive lymphomas. Further, we identified ENO1 as an independent prognostic factor, and it was significantly correlated with overall survival of NHL patients. In addition, we found that ENO1 could promote cell proliferation, regulate cell cycle associated gene and PI3K/AKT signaling pathway in NHLs. Finally, we verified that ENO1 participated in the process of lymphoma cell adhesion mediated drug resistance (CAM-DR). Adhesion to FN or HS5 cells significantly protected OCI-Ly8 and Daudi cells from cytotoxicity compared with those cultured in suspension, and these effects were attenuated when transfected with ENO1-siRNA. Based on the study, we propose that inhibition of ENO1 expression may be a novel strategy for therapy for NHLs patients, and it may be a target for drug resistance. - Highlights: • ENO1 expression is reversely correlated with clinical outcomes of patients with NHLs. • ENO1 promotes the proliferation of NHL cells. • ENO1 regulates cell adhesion mediated drug resistance.

  10. KONSUMSI MIKRONUTRIEN DAN EKSPRESI GEN eNOS3 ALEL INTRO 4a4b PADA PENDERITA HIPERTENSI ETNIK MINANGKABAU

    Directory of Open Access Journals (Sweden)

    Delmi Sulastri

    2011-05-01

    Full Text Available AbstrakGen eNOS3 varian intron 4a4b merupakan salah satu gen yang berhubungan dengan kejadian hipertensi esensial. Kemampuan Gen eNOS3 varian ini untuk mensintesis enzim nitric oxide synthase (NOS berkurang sehingga sintesis Nitric oxide (NO menurun. Senyawa NO adalah suatu senyawa vasoaktif yang menyebabkan vasodilatasi pembuluh darah.Penelitian pada subjek hipertensi dan normotensi berusia 30-65 tahun bertujuan untuk melihat pengaruh mikronutrien terhadap ekspresi gen eNOS3 alel intron 4a4b. 130 subjek, diwawancara pola makannya lalu dilakukan analisis asupan mikronutrien, gen eNOS3, serta kadar NO plasma. Data yang diperoleh dianalisis menggunakan uji T dan chi-square.Kadar NO plasma penderita hipertensi adalah 26.91 + 15.40 μM/L dan normotensi 25.79 + 15.04 μM/L. 55.5% subjek hipertensi memiliki gen eNOS3 varian intron 4b dan 69% subjek normotensi mempunyai varian intron 4a4b. Kadar NO plasma rendah, (66.7% ditemukan pada subjek hipertensi dengan varian intron 4b. Tidak terdapat hubungan bermakna asupan mikronutrien dengan kadar NO plasma pada subjek hipertensi.Hasil ini tidak mendukung pengaruh konsumsi mikronutrien terhadap kadar NO plasma pada penderita hipertensi dengan gen eNOS3 varian intron 4a4b.Kata Kunci : hipertensi esensial, gen eNOS3, kadar NO plasmaAbstracteNOS 3 gene intron 4a4b allel is one of the important genes which is related to hypertesion essensial. This gene expresses the nitric oxide synthase (NOS enzyme which regulates the synthesis of Nitric oxide (NO in human body. NO causes vasodilatation, which decreases peripheral resistant and blood pressure.A research has been done based on cross sectional study on hypertension patients and those with normal blood pressure in the range of 30-65 years old. The main of this research is to evaluate the influence of micronutrient consumption on eNOS3 gene intron 4a4b allel expression in hypertension subjects in Minangkabau ethnicity. 130 subjects interviewed about micronutrient

  11. Disruption of COX-2 and eNOS does not confer protection from cardiovascular failure in lipopolysaccharide-treated conscious mice and isolated vascular rings

    DEFF Research Database (Denmark)

    Stæhr, Mette; Madsen, Kirsten; Vanhoutte, Paul M

    2011-01-01

    (NS 398), disruption of COX-2, endothelium removal, or eNOS deletion (eNOS(-/-)) did not improve vascular reactivity after LPS, while the NO synthase blockers 1400W and N(G)-nitro-l-arginine methyl ester prevented loss of tone. COX-2 and eNOS activities are not necessary for LPS-induced decreases...... in blood pressure, heart rate, and vascular reactivity. Inducible NOS activity appears crucial. COX-2 and eNOS are not obvious therapeutic targets for cardiovascular rescue during gram-negative endotoxemic shock....

  12. Contraceptive prevalence and determinants among women of reproductive age group in Ogbomoso, Oyo State, Nigeria

    Directory of Open Access Journals (Sweden)

    Adeyemi AS

    2016-03-01

    Full Text Available Adewale S Adeyemi,1 Adenike I Olugbenga-Bello,2 Oluwatosin A Adeoye,3 Moshood O Salawu,3 Adesola A Aderinoye,3 Michael A Agbaje1 1Department of Obstetrics and Gynaecology, 2Department of Community Medicine, Faculty of Clinical Sciences, College of Health Sciences, Ladoke Akintola University of Technology (LAUTECH, Osogbo, Osun State, 3Department of Community Medicine, LAUTECH Teaching Hospital, Ogbomoso, Oyo State, Nigeria Background: The fertility rate in Nigeria is 5.7 children per woman. The contraceptive prevalence rate has been found to be low at 15% in 2013, compared to other countries such as the US and Pakistan. Objective: The study aimed to assess the contraceptive prevalence among women of reproductive age in Ogbomoso town, and determinants of use, with a view to make appropriate recommendations that will enhance the uptake of family planning services. Materials and methods: This is a descriptive cross-sectional study conducted with 560 respondents, using a multistage sampling technique. Data were retrieved using a semi-structured, pretested questionnaire. Results: All the respondents were aware of contraception; however, only 49.7% (271 had ever used any method, while 25.4% (69 of the number who had ever used contraception were currently using a method. The methods being used were the traditional type (four [5.9%], natural type (two [3.0%], and modern type (63 [91.1%]. The predictors of contraception use included the age group of 40–49 years (odds ratio [OR] 14.1; confidence interval [CI] 3.06–73.24; P=0.0001; the married women were approximately four times more likely to use contraception than the single women (OR 4.5; CI 3.03–6.72; P<0.0001. The women with tertiary level of education were three times more likely to use contraception than those without formal education (OR 3.1; CI 1.13–9.95; P=0.0268, and the odds ratio of respondents with a positive attitude to using contraception more than those with negative attitude was 2

  13. Cattle cruelty and risks of meat contamination at Akinyele cattle market and slaughter slab in Oyo State, Nigeria.

    Science.gov (United States)

    Adeyemo, Olanike K; Adeyemi, Isaac G; Awosanya, Emmanuel J

    2009-12-01

    Cattle transported to the government-run cattle market and slaughter slab in Akinyele, Oyo State, Nigeria on their final voyage are facing a disturbingly cruel, filthy and unsafe environment that is also raising the risk of contamination of meat sold for human consumption. This report gives a picture of what the cattle have to go through before they are slaughtered. This study also reveals cattle awaiting slaughter in abysmal health conditions, cows pulled with extreme force towards lairage and slaughter slab. Equally disturbing is the filthy situation inside the abattoir where the risk of contamination of meat is significant. Also, poor meat handling, transportation and sales practices subject meat to contamination leading to poor quality and exposure of human consumers to health risk. Development of hygienic slaughter slab operations, improved transportation system for both livestock and meat is therefore recommended; not only for Akinyele, but all abattoirs and slaughter slabs in Nigeria.

  14. Alpha-enolase (ENO1 controls alpha v/beta 3 integrin expression and regulates pancreatic cancer adhesion, invasion, and metastasis

    Directory of Open Access Journals (Sweden)

    Moitza Principe

    2017-01-01

    Full Text Available Abstract Background We have previously shown that in pancreatic ductal adenocarcinoma (PDA cells, the glycolytic enzyme alpha-enolase (ENO1 also acts as a plasminogen receptor and promotes invasion and metastasis formation. Moreover, ENO1 silencing in PDA cells induces oxidative stress, senescence and profoundly modifies PDA cell metabolism. Although anti-ENO1 antibody inhibits PDA cell migration and invasion, little is known about the role of ENO1 in regulating cell-cell and cell-matrix contacts. We therefore investigated the effect of ENO1 silencing on the modulation of cell morphology, adhesion to matrix substrates, cell invasiveness, and metastatic ability. Methods The membrane and cytoskeleton modifications that occurred in ENO1-silenced (shENO1 PDA cells were investigated by a combination of confocal microscopy and atomic force microscopy (AFM. The effect of ENO1 silencing was then evaluated by phenotypic and functional experiments to identify the role of ENO1 in adhesion, migration, and invasion, as well as in senescence and apoptosis. The experimental results were then validated in a mouse model. Results We observed a significant increase in the roughness of the cell membrane due to ENO1 silencing, a feature associated with an impaired ability to migrate and invade, along with a significant downregulation of proteins involved in cell-cell and cell-matrix adhesion, including alpha v/beta 3 integrin in shENO1 PDA cells. These changes impaired the ability of shENO1 cells to adhere to Collagen I and IV and Fibronectin and caused an increase in RGD-independent adhesion to vitronectin (VN via urokinase plasminogen activator receptor (uPAR. Binding of uPAR to VN triggers integrin-mediated signals, which result in ERK1-2 and RAC activation, accumulation of ROS, and senescence. In shENO1 cancer cells, the use of an anti-uPAR antibody caused significant reduction of ROS production and senescence. Overall, a decrease of in vitro and in vivo cell

  15. Enhancing eNOS activity with simultaneous inhibition of IKKβ restores vascular function in Ins2(Akita+/-) type-1 diabetic mice.

    Science.gov (United States)

    Krishnan, Manickam; Janardhanan, Preethi; Roman, Linda; Reddick, Robert L; Natarajan, Mohan; van Haperen, Rien; Habib, Samy L; de Crom, Rini; Mohan, Sumathy

    2015-10-01

    The balance of nitric oxide (NO) versus superoxide generation has a major role in the initiation and progression of endothelial dysfunction. Under conditions of high glucose, endothelial nitric oxide synthase (eNOS) functions as a chief source of superoxide rather than NO. In order to improve NO bioavailability within the vessel wall in type-1 diabetes, we investigated treatment strategies that improve eNOS phosphorylation and NO-dependent vasorelaxation. We evaluated methods to increase the eNOS activity by (1) feeding Ins2(Akita) spontaneously diabetic (type-1) mice with l-arginine in the presence of sepiapterin, a precursor of tetrahydrobiopterin; (2) preventing eNOS/NO deregulation by the inclusion of inhibitor kappa B kinase beta (IKKβ) inhibitor, salsalate, in the diet regimen in combination with l-arginine and sepiapterin; and (3) independently increasing eNOS expression to improve eNOS activity and associated NO production through generating Ins2(Akita) diabetic mice that overexpress human eNOS predominantly in vascular endothelial cells. Our results clearly demonstrated that diet supplementation with l-arginine, sepiapterin along with salsalate improved phosphorylation of eNOS and enhanced vasorelaxation of thoracic/abdominal aorta in type-1 diabetic mice. More interestingly, despite the overexpression of eNOS, the in-house generated transgenic eNOS-GFP (TgeNOS-GFP)-Ins2(Akita) cross mice showed an unanticipated effect of reduced eNOS phosphorylation and enhanced superoxide production. Our results demonstrate that enhancement of endogenous eNOS activity by nutritional modulation is more beneficial than increasing the endogenous expression of eNOS by gene therapy modalities.

  16. Endothelial CaMKII as a regulator of eNOS activity and NO-mediated vasoreactivity.

    Directory of Open Access Journals (Sweden)

    Shubha Murthy

    Full Text Available The multifunctional Ca2+/calmodulin-dependent protein kinase II (CaMKII is a serine/threonine kinase important in transducing intracellular Ca2+ signals. While in vitro data regarding the role of CaMKII in the regulation of endothelial nitric oxide synthase (eNOS are contradictory, its role in endothelial function in vivo remains unknown. Using two novel transgenic models to express CaMKII inhibitor peptides selectively in endothelium, we examined the effect of CaMKII on eNOS activation, NO production, vasomotor tone and blood pressure. Under baseline conditions, CaMKII activation was low in the aortic wall. Consistently, systolic and diastolic blood pressure, heart rate and plasma NO levels were unaltered by endothelial CaMKII inhibition. Moreover, endothelial CaMKII inhibition had no significant effect on NO-dependent vasodilation. These results were confirmed in studies of aortic rings transduced with adenovirus expressing a CaMKII inhibitor peptide. In cultured endothelial cells, bradykinin treatment produced the anticipated rapid influx of Ca2+ and transient CaMKII and eNOS activation, whereas CaMKII inhibition blocked eNOS phosphorylation on Ser-1179 and dephosphorylation at Thr-497. Ca2+/CaM binding to eNOS and resultant NO production in vitro were decreased under CaMKII inhibition. Our results demonstrate that CaMKII plays an important role in transient bradykinin-driven eNOS activation in vitro, but does not regulate NO production, vasorelaxation or blood pressure in vivo under baseline conditions.

  17. Sildenafil promotes eNOS activation and inhibits NADPH oxidase in the transgenic sickle cell mouse penis.

    Science.gov (United States)

    Musicki, Biljana; Bivalacqua, Trinity J; Champion, Hunter C; Burnett, Arthur L

    2014-02-01

    Sickle cell disease (SCD)-associated vasculopathy in the penis is characterized by aberrant nitric oxide and phosphodiesterase (PDE) 5 signaling, and by increased oxidative stress. Preliminary clinical trials show that continuous treatment with PDE5 inhibitor sildenafil unassociated with sexual activity decreases priapic activity in patients with SCD. However, the mechanism of its vasculoprotective effect in the penis remains unclear. We evaluated whether continuous administration of PDE5 inhibitor sildenafil promotes eNOS function at posttranslational levels and decreases superoxide-producing enzyme NADPH oxidase activity in the sickle cell mouse penis. SCD transgenic mice were used as an animal model of SCD. WT mice served as controls. Mice received treatment with the PDE5 inhibitor sildenafil (100 mg/kg/day) or vehicle for 3 weeks. eNOS phosphorylation on Ser-1177 (positive regulatory site), eNOS interactions with heat-shock protein 90 (HSP90) (positive regulator), phosphorylated AKT (upstream mediator of eNOS phosphorylation on Ser-1177), an NADPH oxidase catalytic subunit gp91(phox), and a marker of oxidative stress (4-hydroxy-2-nonenal [HNE]) were measured by Western blot. Effect of continuous sildenafil treatment on eNOS posttranslational activation, NADPH oxidase catalytic subunit, and oxidative stress in the penis of the sickle cell mouse. Continuous treatment with sildenafil reversed (P penis. Sildenafil treatment of WT mice did not affect any of these parameters. Our findings that sildenafil enhances eNOS activation and inhibits NADPH oxidase function in the sickle cell mouse penis offers a vasculoprotective molecular basis for the therapeutic effect of sildenafil in the penis in association with SCD. © 2013 International Society for Sexual Medicine.

  18. Partial deletion of eNOS gene causes hyperinsulinemic state, unbalance of cardiac insulin signaling pathways and coronary dysfunction independently of high fat diet.

    Directory of Open Access Journals (Sweden)

    Cecilia Vecoli

    Full Text Available Abnormalities in eNOS gene, possibly interacting with high fat diet (HFD, affect peripheral vascular function and glucose metabolism. The relative role of eNOS gene, HFD and metabolic derangement on coronary function has not been fully elucidated. We test whether eNOS gene deficiency per se or in association with HFD modulates coronary function through mechanisms involving molecular pathways related to insulin signaling. Wild type (WT, eNOS-/- and eNOS+/- mice were studied. WT and eNOS+/- mice were fed with either standard or HF diet for 16 weeks and compared with standard diet fed eNOS-/-. Glucose and insulin tolerance tests were performed during the last week of diet. Coronary resistance (CR was measured at baseline and during infusions of acetylcholine (Ach or sodium-nitroprusside (SNP to evaluate endothelium-dependent or independent vasodilation, in the Langendorff isolated hearts. Cardiac expression of Akt and ERK genes as evaluation of two major insulin-regulated signaling pathways involved in the control of vascular tone were assessed by western blot. HFD-fed mice developed an overt diabetic state. Conversely, chow-fed genetically modified mice (in particular eNOS-/- showed a metabolic pattern characterized by normoglycemia and hyperinsulinemia with a limited degree of insulin resistance. CR was significantly higher in animals with eNOS gene deletions than in WT, independently of diet. Percent decrease in CR, during Ach infusion, was significantly lower in both eNOS-/- and eNOS+/- mice than in WT, independently of diet. SNP reduced CR in all groups except eNOS-/-. The cardiac ERK1-2/Akt ratio, increased in animals with eNOS gene deletions compared with WT, independently of diet. These results suggest that the eNOS genetic deficiency, associated or not with HFD, has a relevant effect on coronary vascular function, possibly mediated by increase in blood insulin levels and unbalance in insulin-dependent signaling in coronary vessels

  19. Environmental Aspects as Assessment Criteria in Municipal Heat Energy Decisions - Case of Eno Energy Cooperative

    Energy Technology Data Exchange (ETDEWEB)

    Puhakka, Asko [North Karelia Univ. of Applied Sciences, Joensuu (Finland)

    2006-07-15

    The aim of this paper is to provide information whether it is possible to consider the sustainable development perspectives in the decision making of the district energy decision. The new EU-directives concerning public procurements allow the use of environmental aspects as selection criteria. The focus here is on small-scale district heating systems and their fuel-supply chains. The comparable fuels included the analysis are forest chips, heavy fuel oil, light fuel oil and peat. The paper focuses to the concept of the sustainable development and establishes the indicators for ecological-, social- and economical aspects of the district heating. The indicators are utilized in the case study on the Eno Energy Cooperative. The equivalent CO{sub 2} emissions from the production and the combustion of the fuel, the employment impacts of the fuel production and the formation of the price of energy for the consumers are considered. After presenting the sustainable development indicators in the case of Eno Energy Cooperative, the investment models of heat entrepreneurship business are discussed. Finally, we also raise an attention into important aspects to be considered when establishing a local district heating scheme. The indicators used in this presentation show that the use of forest chips in energy production has positive effect through the reduced greenhouse gases. The use of wood in energy production also provides employment opportunities and is more favourable to consumers, because of the steady fuel price when compared to other alternative fuels.

  20. Investigation into The Effect of Arabic Incompetence on The Students’ Performance in Islamic Studies in Ibadan South-East Of Oyo State In Nigeria

    Directory of Open Access Journals (Sweden)

    Kazeem Adekunle Adegoke

    2016-11-01

    Full Text Available Abstract This study investigated the effect of incompetence in Arabic language on students’ performances in Islamic studies in the selected senior secondary schools in Ibadan South-East Local Government Area of Oyo State, Nigeria. The main objective of this study was to ascertain the argument that the poor performance of senior secondary students in Islamic studies is as a result of incompetence and non-proficiency in Arabic language on the side of learners and teachers. The methodology employed in this study was the quantitative approach. Location of the study was Ibadan South-East Local Government Area of Oyo State. Teachers of Islamic studies and students were randomly selected using the stratified random sampling technique from six senior secondary schools. The data gathered were analysed using simple percentages and chi-square statistical analysis. The findings revealed that significant number of students in Senior Secondary School’s poor performance in Islamic studies was due to their incompetence in Arabic as a result of their lack of exposure to the Arabic language and their poor background in Arabic from the previous classes. It also revealed that some of their teachers in Islamic studies were not competent in Arabic reading and writing. Abstrak Penelitian ini menginvestigasi efek ketidakmampuan bahasa Arab terhadap kinerja siswa studi Islam di sekolah-sekolah menengah atas terpilih di Ibadan Tenggara, di Area Pemerintahan Daerah Negara Oyo, Nigeria. Tujuan utama penelitian ini untuk menegaskan argumen bahwa buruknya kinerja siswa sekolah menengah atas pada studi Islam adalah akibat dari ketidakmampuan dan ketidakmahiran bahasa Arab pada peserta didik dan guru. Metode penelitian pendekatan kuantitatif. Lokasi penelitian adalah di Area Pemerintah Daerah Ibadan Tenggara Negara Oyo. Guru dan siswa program studi Islam dipilih secara acak menggunakan teknik stratified random sampling dari enam sekolah menengah atas. Data yang terkumpul

  1. Vasoinhibins Prevent Bradykinin-Stimulated Endothelial Cell Proliferation by Inactivating eNOS via Reduction of both Intracellular Ca2+ Levels and eNOS Phosphorylation at Ser1179

    Directory of Open Access Journals (Sweden)

    Carmen Clapp

    2011-07-01

    Full Text Available Vasoinhibins, a family of antiangiogenic peptides derived from prolactin proteolysis, inhibit the vascular effects of several proangiogenic factors, including bradykinin (BK. Here, we report that vasoinhibins block the BK-induced proliferation of bovine umbilical vein endothelial cells. This effect is mediated by the inactivation of endothelial nitric oxide synthase (eNOS, as the NO donor DETA-NONOate reverted vasoinhibin action. It is an experimentally proven fact that the elevation of intracellular Ca2+ levels ([Ca2+]i upon BK stimulation activates eNOS, and vasoinhibins blocked the BK-mediated activation of phospholipase C and the formation of inositol 1,4,5-triphosphate leading to a reduced release of Ca2+ from intracellular stores. The [Ca2+]i rise evoked by BK also involves the influx of extracellular Ca2+ via canonical transient receptor potential (TRPC channels. Vasoinhibins likely interfere with TRPC-mediated Ca2+ entry since La3+, which is an enhancer of TRPC4 and TRPC5 channel activity, prevented vasoinhibins from blocking the stimulation by BK of endothelial cell NO production and proliferation, and vasoinhibins reduced the BK-induced increase of TRPC5 mRNA expression. Finally, vasoinhibins prevented the BK-induced phosphorylation of eNOS at Ser1179, a post-translational modification that facilitates Ca2+-calmodulin activation of eNOS. Together, our data show that vasoinhibins, by lowering NO production through the inhibition of both [Ca2+]i mobilization and eNOS phosphorylation, prevent the BK-induced stimulation of endothelial cell proliferation. Thus, vasoinhibins help to regulate BK effects on angiogenesis and vascular homeostasis.

  2. Effects of hyperbaric oxygen therapy in enhancing expressions of e-NOS, TNF-α and VEGF in wound healing

    Science.gov (United States)

    Susilo, Imam; Devi, Anita; Purwandhono, Azham; Hadi Warsito, Sunaryo

    2017-05-01

    Wound healing is a physiological process that occurs progressively through overlapping phases. Tissue oxygenation is an important part of the complex regulation for wound healing. Hyperbaric Oxygen (HBO) therapy is a method of increasing oxygen delivery to tissues. The therapy improves tissue oxygenation and stimulates the formation of H2O2 as a secondary messenger for Tumour Necrosis Factor alpha (TNF α), e-NOS, VEGF and Nuclear Factor Kappa Beta phosphorylation (NF-Kb) which play an important role in the rapid transcription of a wide variety of genes in response to extracellular stimuli. This study aims to determine the effects of Hyperbaric Oxygen therapy in enhancing the expressions of e-NOS, TNF-α, VEGF and wound healing. This study is an animal study with a ‘randomized control group of pre-test and post test design’ on 28 Wistar rats. Randomly, the rats were divided into 4 groups with 7 rats in each group. The HBO treatment group 1 received 5 sessions of HBO 2.4 ATA in 3 × 30 minutes; the HBO treatment group 2 received 10 sessions of HBO 2.4 ATA in 3 × 30 minutes; and each of the control groups were without HBO. Each of the 28 male rats were given a full thickness excisional wound of 1 × 1cm. Examinations of e-NOS, TNF-α, VEGF expressions and wound healing were performed on day-0 (pre-HBO) and day-5 HBO or on day-0 (pre-HBO) and day-10 HBO. The resultsshowthat the Hyperbaric Oxygen therapy can improve e-NOS (p=0.02), TNF-α (p= 0.02), VEGF expression (p=0.02) and wound healing (p=0.002) significantly in the provision of HBO 2.4 ATA for 3 × 30 minutes in 5 sessions over 5 consecutive days. While the 10 sessions of HBO 2.4 ATA for 3 × 30 minutes over 10 consecutive days only increase e-NOS (p=0.02), TNF-α (p=0.04), VEGF expression significantly (p=0.03) but do not improve wound healing significantly (p=0.3) compared with no HBO. The study concludes that HBO can improve the expressions of e-NOS, TNF-α, VEGF and wound healing in the provision of HBO

  3. Screening of antibiotics and chemical analysis of penicillin residue in fresh milk and traditional dairy products in Oyo state, Nigeria

    Directory of Open Access Journals (Sweden)

    Isaac Olufemi Olatoye

    2016-09-01

    Full Text Available Background and Aim: There are global public health and economic concerns on chemical residues in food of animal origin. The use of antibiotics in dairy cattle for the treatment of diseases such as mastitis has contributed to the presence of residues in dairy products. Penicillin residues as low as 1 ppb can lead to allergic reactions and shift of resistance patterns in microbial population as well as interfere with the processing of several dairy products. Antibiotic monitoring is an essential quality control measure in safe milk production. This study was aimed at determining antibiotic residue contamination and the level of penicillin in dairy products from Fulani cattle herds in Oyo State. Materials and Methods: The presence of antibiotic residues in 328 samples of fresh milk, 180 local cheese (wara, and 90 fermented milk (nono from Southwest, Nigeria were determined using Premi® test kit (R-Biopharm AG, Germany followed by high-performance liquid chromatography analysis of penicillin-G residue. Results: Antibiotic residues were obtained in 40.8%, 24.4% and 62.3% fresh milk, wara and nono, respectively. Penicillin-G residue was also detected in 41.1% fresh milk, 40.2% nono and 24.4% wara at mean concentrations of 15.22±0.61, 8.24±0.50 and 7.6±0.60 μg/L with 39.3%, 36.7% and 21.1%, respectively, containing penicillin residue above recommended Codex maximum residue limit (MRL of 5 μg/L in dairy. There was no significant difference between the mean penicillin residues in all the dairy products in this study. Conclusion: The results are of food safety concern since the bulk of the samples and substantial quantities of dairy products in Oyo state contained violative levels of antibiotic residues including penicillin residues in concentrations above the MRL. This could be due to indiscriminate and unregulated administration of antibiotics to dairy cattle. Regulatory control of antibiotic use, rapid screening of milk and dairy farmers

  4. An Eulerian method for computation of multimaterial impact with ENO shock-capturing and sharp interfaces

    CERN Document Server

    Udaykumar, H S; Belk, D M; Vanden, K J

    2003-01-01

    A technique is presented for the numerical simulation of high-speed multimaterial impact. Of particular interest is the interaction of solid impactors with targets. The computations are performed on a fixed Cartesian mesh by casting the equations governing material deformation in Eulerian conservation law form. The advantage of the Eulerian setting is the disconnection of the mesh from the boundary deformation allowing for large distortions of the interfaces. Eigenvalue analysis reveals that the system of equations is hyperbolic for the range of materials and impact velocities of interest. High-order accurate ENO shock-capturing schemes are used along with interface tracking techniques to evolve sharp immersed boundaries. The numerical technique is designed to tackle the following physical phenomena encountered during impact: (1) high velocities of impact leading to large deformations of the impactor as well as targets; (2) nonlinear wave-propagation and the development of shocks in the materials; (3) modelin...

  5. Identification and Function Analysis of enolase Gene NlEno1 from Nilaparvata lugens (Stål) (Hemiptera:Delphacidae)

    Science.gov (United States)

    Wang, Wei-Xia; Li, Kai-Long; Chen, Yang; Lai, Feng-Xiang; Fu, Qiang

    2015-01-01

    The enolase [EC 4.2.1.11] is an essential enzyme in the glycolytic pathway catalyzing the conversion of 2-phosphoglycerate (2-PGE) to phosphoenolpyruvate (PEP). In this study, a full-length cDNA encoding α-enolase was cloned from rice brown planthopper (Nilaparvata lugens) and is provisionally designated as NlEno1. The cDNA sequence of NlEno1 was 1,851 bp with an open reading frame (ORF) of 1,305 bp and encoding 434 amino acids. The deduced protein shares high identity of 80–87% with ENO1-like protein from Hemiptera, Diptera, and Lepidoptera speices. The NlEno1 showed the highest mRNA expression level in hemolymph, followed by fat body, salivary gland, ovaries and egg, and showed trace mRNA levels in testis. The mRNA of NlEno1 showed up-regulated level in virulent N. lugens population Mudgo, IR56 and IR42 when compared with TN1 population. Injection of double-stranded RNA (dsRNA) of NlEno1 into the adults significantly down-regulated the NlEno1 mRNA level along with decreased eggs and offspring. Moreover, injection of NlEno1-dsRNA decreased mRNA level of Vitellogenin (Vg) gene. These results showed that the NlEno1, as a key glycolytic enzyme, may play roles in regulation of fecundity and adaptation of N. lugens to resistant rice varieties. PMID:26056319

  6. PSYCHOSOCIAL INFLUENCE OF HEARING IMPAIRMENT ON THE INTERPERSONAL BEHAVIOR OF YOUTHS WITH HEARING IMPAIRMENT IN OYO STATE, NIGERIA

    Directory of Open Access Journals (Sweden)

    Osisanya AYO

    2013-03-01

    Full Text Available Individuals with hearing impairment are confronted with a lot of problems due to the condition of their disability. This has a negative impact on their social and psychological well-being with multiplying effect on their interpersonal relationship. Therefore, this study investigated the psycho-social influence of hearing impairment on interpersonal behavior of youths with hearing loss.MethodologyThe study adopted a survey research design. A sample consisting of 211 participants with hearing loss were purposively selected from the Federal College of Education (Special Oyo, Nigeria. A questionnaire, part of Psycho-social Competence Scale (PCS, was used for data collection with reliability coefficient of 0.72.ResultsThe findings revealed that hearing impairement affects social interaction of youths with hearing impairment, hearing loss affects emotional well-being of youths with hearing impairment and youths with hearing impairment feel inferior in company of persons without hearing impairment. Based on this, it was recommended that a friendly home environment should be made and youths with hearing impairment should be advised to accept their loss and take it as a challenge that can be used to achieve a better end and the society should have right attitude and beliefs toward youths with hearing impairment.

  7. Effect of brain-based learning strategy on students achievement in senior secondary school mathematics in Oyo State, Nigeria

    Directory of Open Access Journals (Sweden)

    Samuel Adejare Awolola

    2011-06-01

    Full Text Available One dominant factor on how well students learn mathematics is the quality of teaching. Studies have shown that typical mathematics classroom is frosted with teaching technique that centered on explain – practice – memorize. There is a paucity particularly in Nigeria. This study therefore, investigated the effect of brain-based learning strategy on the achievement regarding the learning of Mathematics of 522 Senior Secondary School Students in Oyo State, Nigeria. The moderator effect of cognitive style was also examined on independent variable (instructional strategy and dependent variable (mathematics achievement. The study adopted a pretest-posttest non-equivalent control group design in a quasi – experimental setting. The ANCOVA statistic was used to analyzed the data collected fro the study. The result revealed significant main effect of treatment, (F(1,510 = 75.0; P < 0.05, cognitive style (F(1,510 = 23.78; P < 0.05 and significant interaction effect of treatment and cognitive style (F(1,510 = 5.027; P < 0.05 on achievement in mathematics. The result showed that brain-based instructional strategy enhanced students’ achievement in mathematics more than the conventional lecture method. It is therefore recommended that Teachers of mathematics should adopt the strategy in teaching mathematics in senior secondary school.

  8. International note: awareness and context of cyber-harassment among secondary school students in Oyo state, Nigeria.

    Science.gov (United States)

    Olumide, Adesola O; Adams, Patricia; Amodu, Olukemi K

    2015-02-01

    We determined the awareness and context of cyber-harassment among secondary school students (653 survey respondents and 18 in-depth interviewees) in Oyo state, Nigeria. Respondents' mean age was 14.2 ± 2.2 years and 53.9% were aware of cyber-harassment occurring in their school or among their friends. Cyber-harassment was often perpetrated via phone calls (62.5%), text messaging (36.9%), chat rooms (28.7%), through pictures or video clips sent via mobile phones (11.9%), emails (6.8%) or websites (5.9%). Cyber-harassment behaviours mentioned were the use of abusive words (25.4%), saying mean things or making fun of the victim (13.9%), solicitations for relationships (7.9%) or sex (6.8%) and spreading rumours about the victim (6.8%). In-depth interviewees recounted experiences of cyber-harassment suffered by their friends. Many were relationship-related, sexual solicitations and threats and corroborated quantitative findings. Respondents are aware of cyber-harassment occurring among students in the study area. Comprehensive interventions to address the problem need to be instituted. Copyright © 2014 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  9. Endothelial dysfunction in children with obstructive sleep apnea is associated with epigenetic changes in the eNOS gene.

    Science.gov (United States)

    Kheirandish-Gozal, Leila; Khalyfa, Abdelnaby; Gozal, David; Bhattacharjee, Rakesh; Wang, Yang

    2013-04-01

    Obstructive sleep apnea (OSA) is a highly prevalent disorder that has been associated with an increased risk for cardiovascular morbidity, even in children. However, not all children with OSA manifest alterations in endothelial postocclusive hyperemia, an endothelial nitric oxide synthase (eNOS)-dependent response. Since expression of the eNOS gene is regulated by epigenetic mechanisms and OSA may cause epigenetic modifications such as DNA hypermethylation, we hypothesized that epigenetic modifications in the eNOS gene may underlie the differential vascular phenotypes in pediatric OSA. Age-, sex-, ethnicity-, and BMI-matched prepubertal children with polysomnographically confirmed OSA and either normal (OSAn) or abnormal (OSAab) postocclusive hyperemic responses, assessed as the time to attain peak reperfusion flow (Tmax) by laser Doppler flowmetry, were recruited. Blood genomic DNA was assessed for epigenetic modifications in the eNOS gene using pyrosequencing. Children with no evidence of OSA or endothelial dysfunction served as a control group. The study comprised 36 children with OSA (11 with OSAab and 25 with OSAn) and 35 children in the control group. Overall, the mean age was 7.5 ± 2.4 years, 65% were boys, and 30% were obese; mean apnea-hypopnea index was 18 ± 8.6/h of sleep for the children with OSA. Tmax was 66.7 ± 8.8 s in the OSAab group and 30.1 ± 8.3 s in the OSAn group (P < .001). Pyrosequencing of the proximal promoter region of the eNOS gene revealed no significant differences in six of the seven CpG sites. However, a CpG site located at position -171 (relative to transcription start site), approximating important transcriptional elements, displayed significantly higher methylation levels in the OSAab group as compared with the OSAn or control groups (81.5% ± 3.5%, 74.8% ± 1.4%, and 74.5% ± 1.7%, respectively; P < .001). eNOS mRNA expression levels were assessed in a separate group of children and were significantly reduced in the OSAab

  10. Estrogen Receptor Signaling and the PI3K/Akt Pathway Are Involved in Betulinic Acid-Induced eNOS Activation

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    Nicolas Hohmann

    2016-07-01

    Full Text Available Betulinic acid (BA is a naturally occurring pentacyclic triterpenoid with anti-inflammatory, antiviral and anti-cancer properties. Beneficial cardiovascular effects such as increased nitric oxide (NO production through enhancement of endothelial NO synthase (eNOS activity and upregulation of eNOS expression have been demonstrated for this compound. In the present study, immortalized human EA.hy 926 endothelial cells were incubated for up to 1 h with 1–100 µM BA and with the phosphatidylinositol-3-kinase (PI3K inhibitors LY294002 and wortmannin, or the estrogen receptor (ER antagonist ICI 182,780. Phosphorylation status of eNOS and total eNOS protein were analyzed by Western blotting using a serine 1177 phosphosite-specific antibody. Bioactive NO production was assessed by determination of cGMP content in rat lung fibroblasts (RFL-6 reporter cells. Short-term incubation of EA.hy 926 cells with BA resulted in eNOS phosphorylation at the serine 1177 residue in a concentration- and time-dependent manner with a half-maximal effective concentration of 0.57 µM. This was associated with an enhanced production of NO. BA-induced eNOS phosphorylation and NO production was completely blocked by pretreatment with ICI 182,780, and was attenuated by pretreatment with the PI3K inhibitors wortmannin and LY294002. These results indicate that fast non-genomic effects of ER with downstream signaling through the PI3K/Akt pathway and consecutive eNOS phosphorylation at serine 1177 are involved in BA-induced eNOS activation.

  11. Alteration in cardiac uncoupling proteins and eNOS gene expression following high-intensity interval training in favor of increasing mechanical efficiency

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    Fallahi, Ali Asghar; Shekarfroush, Shahnaz; Rahimi, Mostafa; Jalali, Amirhossain; Khoshbaten, Ali

    2016-01-01

    Objective(s): High-intensity interval training (HIIT) increases energy expenditure and mechanical energy efficiency. Although both uncoupling proteins (UCPs) and endothelial nitric oxide synthase (eNOS) affect the mechanical efficiency and antioxidant capacity, their effects are inverse. The aim of this study was to determine whether the alterations of cardiac UCP2, UCP3, and eNOS mRNA expression following HIIT are in favor of increased mechanical efficiency or decreased oxidative stress. Mat...

  12. FEATURES OF THE CLINICAL SIGNIFICANCE OF POLYMORPHIC VARIANTS OF ENOS AND AGTR2 GENES IN PATIENTS WITH CAD

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    A. L. Khokhlov

    2016-01-01

    Full Text Available Coronary heart disease (CHD is a major cause of mortality. Morphological substrate of CHD in most cases is atherosclerosis, which is based on structural genes polymorphism eNOS and AGTR2. The aim of the study was to study the prevalence of eNOS and AGTR2 genes in patients with coronary artery disease and the association of these genes with coronary heart disease. The study involved 187 patients aged 36 to 86 years (62,2±11,2 with different forms of CHD: stable and unstable angina, myocardial infarction and 45 people without CHD. Determination of gene polymorphisms was performed by real-time PCR analyzer of nucleic acids IQ 5 Bio-Rad. Statistical analysis was performed using Statistica 10.0. The study revealed a significant difference between the incidence of homozygous AA allelic variant gene AGTR2 group of patients with myocardial infarction and the comparison group; polymorphic variant AA AGTR2 gene is associated with earlier onset of coronary artery disease; It found that carriers of the polymorphic variant gene GA AGTR2 beginning statistically CHD occurred significantly later than in carriers of alleles GG and AA; age CHD debut TT allele carriers of the eNOS gene is associated with an earlier onset of the disease and statistically significantly different from the age of first CHD in carriers of alleles of polymorphic variants of GG and GT; revealed a positive correlation between the polymorphic allele AGTR2 gene with the presence of arterial hypertension in patients with coronary artery disease; It determined that the T allele carriers of the polymorphic gene eNOS is associated more early onset of hypertension, found the association of the polymorphic allele gene AGTR2 the need to use higher doses of ACE inhibitor — perindopril.

  13. Immunomodulatory effects of royal jelly on aorta CD3, CD68 and eNOS expression in hypercholesterolaemic rats

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    Amal Attia El-Morsy Ibrahim

    2014-08-01

    RJ administration (300 mg/kg/day with CH, produced a counteractive effect, represented in recompense of biochemical alteration, CD4 and CD8 expression. RJ intake also amended the histological picture. The immunohistochemical picture revealed a decrease in CD3, CD86 and eNOS in the aortic tissue. These findings attributed to the significant immunomodulatory effect of RJ remedy suppress deleterious effects of hypercholesterolaemia.

  14. Prevalence of endothelial nitric oxide synthase (eNOS) gene exon 7 Glu298Asp variant in North Eastern India

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    Shankarishan, Priyanka; Borah, Prasanta Kumar; Ahmed, Giasuddin; Mahanta, Jagadish

    2011-01-01

    Background & objectives Endothelial nitric oxide is a potent vasodilator and impairment of its generation brought about by gene polymorphism is considered a major predictor for several diseases. A single nucleotide polymorphism G894T within exon 7 of endothelial nitric oxide synthase (eNOS-7) gene, resulting in a replacement of glutamic acid by aspartic acid, has been studied as a putative candidate gene for cardiovascular diseases. The pattern of eNOS-7 Glu298Asp variant in the Indian population is poorly known. The present study was planned to determine the prevalence of the variant of this gene among tea garden community in Assam, North-East India with high prevalence of hypertension. Methods Study participants of both sex aged ≥18 yr were recruited randomly from temporary field clinics established in tea gardens of Dibrugarh, Assam. Genomic DNA was extracted from 409 subjects by the conventional phenol-chloroform method. The prevalence of the eNOS exon 7 Glu298Asp variant was determined by polymerase chain reaction and restriction fragment length polymorphism analysis. Results The study population was in Hardy-Weinberg Equilibrium. The frequency of the eNOS GG, GT and TT genotypes was found to be 75, 22 and 3 per cent respectively and did not show any significant difference in gender wise analysis. Interpretation & conclusions Our results showed that the prevalence of the homozygous GG genotype was high (75%) and the rare mutant genotype (homozygous, TT) was 3 per cent in a population at risk with cardiovascular disease. Such population-based data on various polymorphisms can ultimately be exploited in pharmacogenomics. PMID:21623032

  15. Substance P ameliorates tumor necrosis factor-alpha-induced endothelial cell dysfunction by regulating eNOS expression in vitro.

    Science.gov (United States)

    Piao, Jiyuan; Hong, Hyun Sook; Son, Youngsook

    2018-04-01

    The aim of this study was to explore the beneficial effects of SP on NO production and inflammation-induced vascular endothelium cell death. To mimic the inflammatory environment, TNF-α was treated with HUVECs, and SP was added prior to TNF-α to determine its protective effect. WST-1 assay was performed to detect cell viability. NO level in conditioned medium was measured by Griess Reagent System. The protein level of cleaved caspase-3, eNOS, and phosphorylated Akt was detected by Western blot analysis. TNF-α declined endothelial cell viability by downregulating Akt and NO production. TNF-α-induced cell death was reliably restored by NO, confirming the requirement of NO for cell survival. By contrast, pretreatment of SP attenuated TNF-α-induced cellular apoptosis, accompanied by an increase in the phosphorylation of Akt, eNOS expression, and NO production. Blockage of NK-1R, phosphorylated Akt or eNOS by CP-96345, A6730, or L-NAME entirely eliminated the effect of SP. SP can protect the vascular endothelium against inflammation-induced damage through modulation of the Akt/eNOS/NO signaling pathway. © 2018 John Wiley & Sons Ltd.

  16. Malaria knowledge and agricultural practices that promote mosquito breeding in two rural farming communities in Oyo State, Nigeria

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    Oshiname Frederick O

    2010-04-01

    Full Text Available Abstract Background Agricultural practices such as the use of irrigation during rice cultivation, the use of ponds for fish farming and the storage of water in tanks for livestock provide suitable breeding grounds for anthropophylic mosquitoes. The most common anthropophylic mosquito in Nigeria which causes much of the morbidity and mortality associated with malaria is the anopheles mosquito. Farmers are therefore at high risk of malaria - a disease which seriously impacts on agricultural productivity. Unfortunately information relating to agricultural practices and farmers' behavioural antecedent factors that could assist malaria programmers plan and implement interventions to reduce risk of infections among farmers is scanty. Farmers' knowledge about malaria and agricultural practices which favour the breeding of mosquitoes in Fashola and Soku, two rural farming communities in Oyo State were therefore assessed in two rural farming communities in Oyo State. Methods This descriptive cross-sectional study involved the collection of data through the use of eight Focus Group Discussions (FGDs and the interview of 403 randomly selected farmers using semi-structured questionnaires. These sets of information were supplemented with observations of agricultural practices made in 40 randomly selected farms. The FGD data were recorded on audio-tapes, transcribed and subjected to content analysis while the quantitative data were analyzed using descriptive and inferential statistics. Results Most respondents in the two communities had low level of knowledge of malaria causation as only 12.4% stated that mosquito bite could transmit the disease. Less than half (46.7% correctly mentioned the signs and symptoms of malaria as high body temperature, body pains, headache, body weakness and cold/fever. The reported main methods for preventing mosquito bites in the farming communities included removal of heaps of cassava tuber peelings (62.3%, bush burning

  17. Activities and influence of veterinary drug marketers on antimicrobial usage in livestock production in Oyo and Kaduna States, Nigeria

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    Olufemi Ernest Ojo

    2017-09-01

    Full Text Available Antimicrobial usage in animals contributes to the emergence of antimicrobial resistant bacterial strains. Investigations were carried out on how the characteristics, knowledge, attitude and practices of antimicrobial marketers influenced antimicrobials usage in animal production in Oyo and Kaduna States, Nigeria. Focus group discussions, in-depth interviews and structured questionnaires were used to gather information about the characteristics and activities of antimicrobial marketers. Overall, 70 (56.9 % of 123 marketers had post-secondary education while 76 (61.8 % were trained on the use of antimicrobials. Eighteen (14.6 % of the marketers were licensed veterinarians. Only 51 (41.5 % marketers displayed adequate knowledge about antimicrobials and antimicrobial usage. Sixty-seven (54.6 % marketers requested a prescription before selling antimicrobials while 113 (91.9 % marketer recommended antimicrobials for use in animals. Two-third of the marketers (66.7 % prescribed antimicrobials without physically examining sick animals but based their prescriptions on verbal reports of clinical signs by farmers and on their personal experience. Marketers with higher educational qualification displayed more adequate knowledge of antimicrobials and antimicrobial usage than those with basic education background only. More years of experience in antimicrobial marketing did not translate to better knowledge on antimicrobial usage. Only 45 (36.6 % respondents were aware of the existence of regulatory agencies monitoring the use of antimicrobials in animals. Farmers ignored the services of veterinarians in the diagnosis and control of animal diseases but resorted to drug marketers for help. Effective communication of existing legislations on antimicrobial usage, improved access to veterinary services and strict enforcement of regulatory policies are recommended for checking non-judicious use of antimicrobial agents in animal production. Sales of

  18. Efectos ecológicos del fenómeno ENOS en Colombia

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    Yesid Carvajal

    2014-06-01

    Full Text Available El fenómeno ENOS, tiene un sustancial efecto sobre las variaciones del clima a nivel mundial; por lo tanto, no sorprende que sus efectos tengan un impacto ecológico y socioeconómico fuerte, alterando la seguridad alimentaria de los países a nivel mundial. Ante este panorama, es comprensible que haya despertado el mayor interés mundial, no sólo en los especialistas en meteorología y oceanografía sino también entre biólogos, ecólogos, físicos, matemáticos, agrónomos, hidrólogos, economistas, sociólogos y planificadores, entre otros. En el presente documento, se muestra algunos de los principales efectos ecológicos en Colombia durante las fases extremas cálida (El Niño y fría (La Niña, indicando que es una necesidad urgente, orientar la investigación en sus causas, consecuencias e impactos.

  19. Association of eNOS and ACE gene polymorphisms and plasma nitric oxide with risk of non-small cell lung cancer in South India.

    Science.gov (United States)

    Peddireddy, Vidyullatha; Badabagni, Siva Prasad; Gundimeda, Sandhya Devi; Mundluru, Hema Prasad

    2018-01-01

    The role of ACE and eNOS gene polymorphisms and their association with various cancers were reported. However, their role in the lung cancer is unclear. In this study, we analyzed eNOS and ACE gene polymorphisms and the risk of non-small cell lung cancer (NSCLC) in South Indian population. For the eNOS gene, the homozygous "AA" genotypic frequency was significantly associated with NSCLC with an overall risk of 3.6-fold (P = 0.006, odds ratio = 3.58, 95% confidence interval = 1.66, 7.723). The heterozygous "I/D" genotypic frequency of ACE gene was significantly higher in NSCLC patients when compared to the controls with a 2.29-fold risk for NSCLC. Multiple regression analyses indicated that gender, smoking status, and polymorphisms in eNOS and ACE genes as the strongest predicting factors for an increased susceptibility to NSCLC. We report for the first time that polymorphisms in the eNOS "A/A" (homozygous mutant) and ACE "I/D" genotypes might contribute to the increased risk of NSCLC in the South Indian population. © 2016 John Wiley & Sons Ltd.

  20. Investigation of gene expression and serum levels of PIN1 and eNOS with high blood pressure in patients with Alzheimer disease.

    Science.gov (United States)

    Azimi, Mina; Nikanfar, Masoud; Khakikhatibi, Fatemeh; Rahbarghazi, Reza; Nourazarian, Seyed Manuchehr; Biray Avci, Cigir; Nourazarian, Alireza

    2017-09-01

    According to evidence, Alzheimer's disease is known as one of the most serious neurodegenerative diseases, for which hypertension has been observed to be a key risk factor. Therefore, this study aims to examine the relationship between the PIN1 and eNOS genes expression, as well as serum levels and hypertension in Alzheimer's disease sufferers. Blood samples were obtained from subjects who were divided into four groups: the control group, normotensive Alzheimer's patients, the Alzheimer's sufferers group with hypertension, and the healthy group with only hypertension, considering the inhibition of confounding factors. Thereafter, eNOS and PIN1 genes expression along with serum levels were studied. Based on the obtained results, a statistically significant correlation didn't exist between serum level of PIN1 and the systolic and diastolic blood pressure, between serum level of eNOS and diastolic blood pressure in the norm tension Alzheimer's disease patients, between serum levels of PIN1, eNOS and systolic blood pressure, and between serum eNOS and systolic and diastolic blood pressure in the patients with hypertension (pdiseases in Alzheimer's disease. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Effects of atorvastatin and T-786C polymorphism of eNOS gene on plasma metabolic lipid parameters.

    Science.gov (United States)

    Zago, Vanessa Helena de Souza; Santos, José Eduardo Tanus dos; Danelon, Mirian Regina Gardin; Silva, Roger Marcelo Mesquita da; Panzoldo, Natália Baratella; Parra, Eliane Soler; Alexandre, Fernanda; Virgínio, Vítor Wilson de Moura; Quintão, Eder Carlos Rocha; Faria, Eliana Cotta de

    2013-01-01

    Endothelial nitric oxide synthase (eNOS) activity may be modulated by high-density lipoprotein cholesterol (HDL-C), statins or polymorphisms, such as the T-786C of eNOS. This study aimed at evaluating if the T-786C polymorphism is associated with changes of atorvastatin effects on the lipid profile, on the concentrations of metabolites of nitric oxide (NO) and of high sensitivity C-reactive protein (hsCRP). Thirty male volunteers, asymptomatic, aged between 18 and 56 years were genotyped and classified according to absence (TT, n = 15) or presence (CC, n = 15) of the polymorphism. They were randomly selected for the use of placebo or atorvastatin (10 mg/day/14 days). After each treatment lipids, lipoproteins, HDL2 and HDL3 composition, cholesteryl ester transfer protein (CETP) activity, metabolites of NO and hsCRP were evaluated. The comparisons between genotypes after placebo showed an increase in CETP activity in a polymorphism-dependent way (TT, 12±7; CC, 22±12; p < 0.05). The interaction analyses between treatments indicated that atorvastatin has an effect on cholesterol, LDL, nitrite and lipid-protein ratios (HDL2 and HDL3) (p < 0.001) in both genotypes. Interestingly, we observed genotype/drug interactions on CETP (p < 0.07) and lipoprotein (a) (Lp(a)) (p < 0.056), leading to a borderline decrease in CETP, but with no effect on Lp(a). HsCRP showed no alteration. These results suggest that statin treatment may be relevant for primary prevention of atherosclerosis in patients with the T-786C polymorphism of eNOS, considering the effects on lipid metabolism.

  2. eNOS se correlaciona com a biogênese mitocondrial em corações com cardiopatia congênita e cianose eNOS correlates with mitochondrial biogenesis in hearts of congenital heart disease with cyanosis

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    Juan Xiao

    2012-09-01

    Full Text Available FUNDAMENTO: O programa de biogênese mitocondrial no coração parece apresentar remodelação adaptativa após estresse biomecânico e oxidativo. Os mecanismos adaptativos que protegem o metabolismo do miocárdio durante a hipóxia são coordenados, em parte, pelo óxido nítrico (NO. OBJETIVO: Observar a biogênese mitocondrial e expressão do óxido nítrico sintase (NOS em corações de cardiopatia congênita com cianose; discutir a resposta mitocondrial à hipóxia crônica do miocárdio. MÉTODOS: Foram investigados 20 pacientes com defeitos cardíacos cianóticos (n = 10 ou acianóticos (n = 10. Foram estudadas amostras do miocárdio na via de saída ventricular direita, tomadas durante a operação. A análise morfométrica de mitocôndrias foi realizada por microscopia eletrônica de transmissão. A relação mtDNA/nDNA foi determinada com PCR em tempo real. Os níveis de transcrição da subunidade I da citocromo c oxidase (COXI, coativador-1α do receptor γ ativado por proliferador de peroxissoma (PGC-1α, o fator respiratório nuclear 1 (NRF1, e fator de transcrição mitocondrial A (Tfam foram detectados por reação em cadeia da polimerase via transcriptase reversa (RT-PCR ativado por fluorescência em tempo real. Os níveis proteicos de COXI e nNOS, iNOS e eNOS foram medidos por técnica de Western Blot. RESULTADOS: A densidade volumétrica mitocondrial (Vv e a densidade numérica (Nv foram significativamente elevadas em pacientes com cianose, em comparação com a cardiopatia congênita acianótica. MtDNA elevada e suprarregulação dos níveis de COXI, PGC-1 α, NRF1 e Tfam mRNA foram observadas em pacientes cianóticos. Os níveis de proteína de COXI e eNOS foram significativamente maiores no miocárdio de pacientes cianóticos que nos de acianóticos. Os níveis de transcrição do PGC-1α se correlacionam com os níveis de eNOS. CONCLUSÃO: A biogênese mitocondrial é ativada no miocárdio da via de saída ventricular na

  3. Relationship between endothelial nitric oxide synthase (eNOS) and natural history of intracranial aneurysms: meta-analysis.

    Science.gov (United States)

    Paschoal, Eric Homero Albuquerque; Yamaki, Vitor Nagai; Teixeira, Renan Kleber Costa; Paschoal Junior, Fernando Mendes; Jong-A-Liem, Glaucia Suzanna; Teixeira, Manoel Jacobsen; Yamada, Elizabeth Sumi; Ribeiro-Dos-Santos, Ândrea; Bor-Seng-Shu, Edson

    2018-01-01

    The aneurysmal subarachnoid hemorrhage is a major public health problem described as a sudden drastic event with no warning symptoms and high morbidity and mortality rates. The role of the endothelial isoform of nitric oxide synthase gene polymorphism in intracranial aneurysms (IAs) is still a matter of controversy with divergent findings among European, American, and Asian populations. Our study purposed to test the association between intracranial aneurysms formation and nitric oxide gene polymorphisms through a systematic review and meta-analysis. Systematic search on Medline, Lilacs, and EMBASE was performed. The primary search resulted in 139 papers, out of which 9 met our inclusion criteria after a full text analysis. The dominant T786C model found a significant association with IA (OR 1.22, 95 % CI 1.04-1.44, p = 0.01), so did studies of the recessive T786C model (OR 0.37, 95 % CI 0.30-0.45, p < 0.0001) but with opposite effect. Our findings support the presence of the T786C polymorphism as a predictor for the development of intracranial aneurysm in the cerebral vascular system. More studies are necessary in order to elucidate the pathways of the endothelial nitric oxide synthase (eNOS) in cerebrovascular diseases and in defining how different allelic combinations of the eNOS gene single-nucleotide polymorphism (SNP) could favor this pathological process.

  4. Prunella vulgaris Suppresses HG-Induced Vascular Inflammation via Nrf2/HO-1/eNOS Activation

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    Ho Sub Lee

    2012-01-01

    Full Text Available Vascular inflammation is an important factor which can promote diabetic complications. In this study, the inhibitory effects of aqueous extract from Prunella vulgaris (APV on high glucose (HG-induced expression of cell adhesion molecules in human umbilical vein endothelial cells (HUVEC are reported. APV decreased HG-induced expression of intercellular adhesion molecule-1 (ICAM-1, vascular cell adhesion molecule-1 (VCAM-1, and E-selectin. APV also dose-dependently inhibited HG-induced adhesion of HL-60 monocytic cells. APV suppressed p65 NF-κB activation in HG-treated cells. APV significantly inhibited the formation of intracellular reactive oxygen species (ROS. HG-stimulated HUVEC secreted gelatinases, however, APV inhibited it. APV induced Akt phosphorylation as well as activation of heme oxygenase-1 (HO-1, eNOS, and nuclear factor E2-related factor 2 (Nrf2, which may protect vascular inflammation caused by HG. In conclusion, APV exerts anti-inflammatory effect via inhibition of ROS/NF-κB pathway by inducing HO-1 and eNOS expression mediated by Nrf2, thereby suggesting that Prunella vulgaris may be a possible therapeutic approach to the inhibition of diabetic vascular diseases.

  5. Sildenafil Ameliorates Gentamicin-Induced Nephrotoxicity in Rats: Role of iNOS and eNOS

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    Mohamed A. Morsy

    2014-01-01

    Full Text Available Gentamicin, an aminoglycoside antibiotic, is used for the treatment of serious Gram-negative infections. However, its usefulness is limited by its nephrotoxicity. Sildenafil, a selective phosphodiesterase-5 inhibitor, was reported to prevent or decrease tissue injury. The aim of this study is to evaluate the potential protective effects of sildenafil on gentamicin-induced nephrotoxicity in rats. Male Wistar rats were injected with gentamicin (100 mg/kg/day, i.p. for 6 days with and without sildenafil. Sildenafil administration resulted in nephroprotective effect in gentamicin-intoxicated rats as it significantly decreased serum creatinine and urea, urinary albumin, and renal malondialdehyde and nitrite/nitrate levels, with a concomitant increase in renal catalase and superoxide dismutase activities compared to gentamicin-treated rats. Moreover, immunohistochemical examination revealed that sildenafil treatment markedly reduced inducible nitric oxide synthase (iNOS expression, while expression of endothelial nitric oxide synthase (eNOS was markedly enhanced. The protective effects of sildenafil were verified histopathologically. In conclusion, sildenafil protects rats against gentamicin-induced nephrotoxicity possibly, in part, through its antioxidant activity, inhibition of iNOS expression, and induction of eNOS production.

  6. NOX4-dependent Hydrogen peroxide promotes shear stress-induced SHP2 sulfenylation and eNOS activation.

    Science.gov (United States)

    Sánchez-Gómez, Francisco J; Calvo, Enrique; Bretón-Romero, Rosa; Fierro-Fernández, Marta; Anilkumar, Narayana; Shah, Ajay M; Schröder, Katrin; Brandes, Ralf P; Vázquez, Jesús; Lamas, Santiago

    2015-12-01

    Laminar shear stress (LSS) triggers signals that ultimately result in atheroprotection and vasodilatation. Early responses are related to the activation of specific signaling cascades. We investigated the participation of redox-mediated modifications and in particular the role of hydrogen peroxide (H2O2) in the sulfenylation of redox-sensitive phosphatases. Exposure of vascular endothelial cells to short periods of LSS (12 dyn/cm(2)) resulted in the generation of superoxide radical anion as detected by the formation of 2-hydroxyethidium by HPLC and its subsequent conversion to H2O2, which was corroborated by the increase in the fluorescence of the specific peroxide sensor HyPer. By using biotinylated dimedone we detected increased total protein sulfenylation in the bovine proteome, which was dependent on NADPH oxidase 4 (NOX4)-mediated generation of peroxide. Mass spectrometry analysis allowed us to identify the phosphatase SHP2 as a protein susceptible to sulfenylation under LSS. Given the dependence of FAK activity on SHP2 function, we explored the role of FAK under LSS conditions. FAK activation and subsequent endothelial NO synthase (eNOS) phosphorylation were promoted by LSS and both processes were dependent on NOX4, as demonstrated in lung endothelial cells isolated from NOX4-null mice. These results support the idea that LSS elicits redox-sensitive signal transduction responses involving NOX4-dependent generation of hydrogen peroxide, SHP2 sulfenylation, and ulterior FAK-mediated eNOS activation. Copyright © 2015 Elsevier Inc. All rights reserved.

  7. Enolase 1 (ENO1 and protein disulfide-isomerase associated 3 (PDIA3 regulate Wnt/β-catenin-driven trans-differentiation of murine alveolar epithelial cells

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    Kathrin Mutze

    2015-08-01

    Full Text Available The alveolar epithelium represents a major site of tissue destruction during lung injury. It consists of alveolar epithelial type I (ATI and type II (ATII cells. ATII cells are capable of self-renewal and exert progenitor function for ATI cells upon alveolar epithelial injury. Cell differentiation pathways enabling this plasticity and allowing for proper repair, however, are poorly understood. Here, we applied proteomics, expression analysis and functional studies in primary murine ATII cells to identify proteins and molecular mechanisms involved in alveolar epithelial plasticity. Mass spectrometry of cultured ATII cells revealed a reduction of carbonyl reductase 2 (CBR2 and an increase in enolase 1 (ENO1 and protein disulfide-isomerase associated 3 (PDIA3 protein expression during ATII-to-ATI cell trans-differentiation. This was accompanied by increased Wnt/β-catenin signaling, as analyzed by qRT-PCR and immunoblotting. Notably, ENO1 and PDIA3, along with T1α (podoplanin; an ATI cell marker, exhibited decreased protein expression upon pharmacological and molecular Wnt/β-catenin inhibition in cultured ATII cells, whereas CBR2 levels were stabilized. Moreover, we analyzed primary ATII cells from mice with bleomycin-induced lung injury, a model exhibiting activated Wnt/β-catenin signaling in vivo. We observed reduced CBR2 significantly correlating with surfactant protein C (SFTPC, whereas ENO1 and PDIA3 along with T1α were increased in injured ATII cells. Finally, siRNA-mediated knockdown of ENO1, as well as PDIA3, in primary ATII cells led to reduced T1α expression, indicating diminished cell trans-differentiation. Our data thus identified proteins involved in ATII-to-ATI cell trans-differentiation and suggest a Wnt/β-catenin-driven functional role of ENO1 and PDIA3 in alveolar epithelial cell plasticity in lung injury and repair.

  8. Alteration in cardiac uncoupling proteins and eNOS gene expression following high-intensity interval training in favor of increasing mechanical efficiency.

    Science.gov (United States)

    Fallahi, Ali Asghar; Shekarfroush, Shahnaz; Rahimi, Mostafa; Jalali, Amirhossain; Khoshbaten, Ali

    2016-03-01

    High-intensity interval training (HIIT) increases energy expenditure and mechanical energy efficiency. Although both uncoupling proteins (UCPs) and endothelial nitric oxide synthase (eNOS) affect the mechanical efficiency and antioxidant capacity, their effects are inverse. The aim of this study was to determine whether the alterations of cardiac UCP2, UCP3, and eNOS mRNA expression following HIIT are in favor of increased mechanical efficiency or decreased oxidative stress. Wistar rats were divided into five groups: control group (n=12), HIIT for an acute bout (AT1), short term HIIT for 3 and 5 sessions (ST3 and ST5), long-term training for 8 weeks (LT) (6 in each group). The rats of the training groups were made to run on a treadmill for 60 min in three stages: 6 min running for warm-up, 7 intervals of 7 min running on treadmill with a slope of 5° to 20° (4 min with an intensity of 80-110% VO2max and 3 min at 50-60% VO2max), and 5-min running for cool-down. The control group did not participate in any exercise program. Rats were sacrificed and the hearts were extracted to analyze the levels of UCP2, UCP3 and eNOS mRNA by RT-PCR. UCP3 expression was increased significantly following an acute training bout. Repeated HIIT for 8 weeks resulted in a significant decrease in UCPs mRNA and a significant increase in eNOS expression in cardiac muscle. This study indicates that Long term HIIT through decreasing UCPs mRNA and increasing eNOS mRNA expression may enhance energy efficiency and physical performance.

  9. Eno-culture and Identity: The installation as a new methodology in Artistic Research and Heritage Education

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    Ruth Marañón Martínez de la Puente

    2018-03-01

    Full Text Available The aesthetic experience and the artistic knowledge always have been connected with the Heritage Education, due to the great importance in rewarding pedagogic processes, specially, in non-formal spaces. In our research, the installation (with its features and competences has turned into the most interesting educational tool to transform the reality of our work’s context: Rioja Alavesa. Thus, across the workshops "Instálate" (organized inside different wineries of the region, we worked the Wine Cultural Heritage (Eno-culture, the Artistic Research and the knowledge based on the sensitive experience. In this article, we showed the results of this experience, proposing the installation as a new interesting and practical method of Artistic Research in Heritage Education. In conclusion, we propose the art-installation as a different key to work the identity, contemporary art, culture and heritage.

  10. Chronic aerobic exercise associated to dietary modification improve endothelial function and eNOS expression in high fat fed hamsters.

    Directory of Open Access Journals (Sweden)

    Beatriz C S Boa

    Full Text Available Obesity is epidemic in the western world and central adipose tissue deposition points to increased cardiovascular morbidity and mortality, independently of any association between obesity and other cardiovascular risk factors. Physical exercise has been used as non-pharmacological treatment to significantly reverse/attenuate obesity comorbidities. In this study we have investigated effects of exercise and/or dietary modification on microcirculatory function, body composition, serum glucose, iNOS and eNOS expression on 120 male hamsters treated for 12 weeks with high fat chow (HF, n = 30 starting on the 21st day of birth. From week 12 to 20, animals were randomly separated in HF (no treatment change, return to standard chow (HFSC, n = 30, high fat chow associated to an aerobic exercise training program (AET (HFEX, n = 30 and return to standard chow+AET (HFSCEX, n = 30. Microvascular reactivity in response to acetylcholine and sodium nitroprusside and macromolecular permeability increase induced by 30 minutes ischemia followed by reperfusion were assessed on the cheek pouch preparation. Total body fat and aorta eNOS and iNOS expression by immunoblotting assay were evaluated on the experimental day. Compared to HFSC and HFSCEX groups, HF and HFEX ones presented increased visceral fat [(mean±SEM (HF4.9±1.5 g and (HFEX4.7±0.9 g vs. (HFSC*3.0±0.7 g and (HFSCEX*1.9±0.4 g/100 g BW]; impaired endothelial-dependent vasodilatation [Ach 10(-8 M (HF87.9±2.7%; (HFSC*116.7±5.9%; (HFEX*109.1±4.6%; (HFSCEX*105±2.8%; Ach10(-6 M (HF95.3±3.1%; (HFSC*126±6.2%; (HFEX*122.5±2.8%; (HFSCEX*118.1±4.3% and Ach10(-4 M (HF109.5±4.8%; (HFSC*149.6±6.6%; (HFEX*143.5±5.4% and (HFSCEX*139.4±5.2%], macromolecular permeability increase after ischemia/reperfusion [(HF40.5±4.2; (HFSC*19.0±1.6; (HFEX*18.6±2.1 and (HFSCEX* 21.5±3.7 leaks/cm2, decreased eNOS expression, increased leptin and glycaemic levels. Endothelial-independent microvascular

  11. A Multilevel Prediction of Physiological Response to Challenge: Interactions among Child Maltreatment, Neighborhood Crime, eNOS and GABRA6

    Science.gov (United States)

    Lynch, Michael; Manly, Jody Todd; Cicchetti, Dante

    2015-01-01

    Physiological response to stress has been linked to variety of healthy and pathological conditions. The current study conducted a multilevel examination of interactions among environmental toxins – i.e., neighborhood crime and child maltreatment – and specific genetic polymorphisms of eNOS and GABRA6. A total of 186 children were recruited at age 4. At this time, the presence or absence of child maltreatment was determined, as was the amount of crime that occurred in their neighborhood during the previous year. At age 9, the children were brought to the lab where their physiological response to a cognitive challenge – i.e., change in the amplitude of RSA – was assessed and DNA samples were collected for subsequent genotyping. Results confirmed that complex G x G, E x E, and G x E interactions were associated with different patterns of RSA reactivity. The implications for future research and evidence-based intervention are discussed. PMID:26535938

  12. Effects of aerobic exercise on the blood pressure, oxidative stress and eNOS gene polymorphism in pre-hypertensive older people.

    Science.gov (United States)

    Zago, Anderson Saranz; Park, Joon-Young; Fenty-Stewart, Nicola; Silveira, Leonardo Reis; Kokubun, Eduardo; Brown, Michael D

    2010-11-01

    The polymorphisms of endothelial nitric oxide synthase (eNOS) are associated with reduced eNOS activity. Aerobic exercise training (AEX) may influence resting nitric oxide (NO) production, oxidative stress and blood pressure. The purpose of this study was to investigate the effect of AEX on the relationship among blood pressure, eNOS gene polymorphism and oxidative stress in pre-hypertensive older people. 118 pre-hypertensive subjects (59 ± 6 years) had blood samples collected after a 12 h overnight fast for assessing plasma NO metabolites (NOx) assays, thiobarbituric acid reactive substances (T-BARS) and superoxide dismutase activity (ecSOD). eNOS polymorphism (T-786C and G-894T) was done by standard PCR methods. All people were divided according to the genotype results (G1: TT/GG, G2: TT/GT + TT, G3: TC + CC/GG, G4: TC + CC/GT + TT). All parameters were measured before and after 6 months of AEX (70% of VO(2 max)). At baseline, no difference was found in systolic and diastolic blood pressure, ecSOD and T-BARS activity. Plasma NOx levels were significantly different between G1 (19 ± 1 μM) and G4 (14.2 ± 0.6 μM) and between G2 (20.1 ± 1.7 μM) and G4 (14.2 ± 0.6 μM). Therefore, reduced NOx concentration in G4 group occurred only when the polymorphisms were associated, suggesting that these results are more related to genetic factors than NO-scavenging effect. After AEX, the G4 increased NOx values (17.2 ± 1.2 μM) and decreased blood pressure. G1, G3 and G4 decreased T-BARS levels. These results suggest the AEX can modulate the NOx concentration, eNOS activity and the relationship among eNOS gene polymorphism, oxidative stress and blood pressure especially in C (T-786C) and T (G-894T) allele carriers.

  13. Evaluation of Protective Immune Responses Induced by Recombinant TrxLp and ENO2 Proteins against Toxoplasma gondii Infection in BALB/c Mice

    Directory of Open Access Journals (Sweden)

    Meng Wang

    2016-01-01

    Full Text Available Toxoplasma gondii is an obligate intracellular parasitic protozoan that can infect almost all species of warm-blooded animals. As any chemical-based drugs could not act against the tissue cyst stage of T. gondii, vaccination may be one of the ideal control strategies. In the present study, two new vaccine candidates, named TgENO2 and TgTrxLp, were purified from Escherichia coli with pET-30a(+ expression system and then were injected into BALB/c mice to evaluate the protective efficacy against acute and chronic toxoplasmosis. The results showed that both the recombinant proteins, either alone or in combination, could elicit strong humoral and cellular immune responses with a higher level of IgG antibodies, IFN-γ, IL-2, CD4+, and CD8+ T cells as compared to those in mice from control groups. After acute challenge with tachyzoites of the GJS strain, mice immunized with rTgTrxLp (8±2.77 d, rTgENO2 (7.4±1.81 d, and rTgTrxLp + rTgENO2 (8.38±4.57 d proteins showed significantly longer survival time than those that received Freund’s adjuvant (6.78±2.08 d and PBS (6.38±4.65 d (χ2 = 9.687, df = 4, P=0.046. The protective immunity of rTgTrxLp, rTgENO2, and rTgTrxLp + rTgENO2 proteins against chronic T. gondii infection showed 69.77%, 58.14%, and 20.93% brain cyst reduction as compared to mice that received PBS. The present study suggested that both TgENO2 and TgTrxLp were potential candidates for the development of multicomponent vaccines against toxoplasmosis.

  14. Lack of protection against rabies in neighbourhood dogs in some peri-urban and rural areas of Ogun and Oyo states, Nigeria.

    Science.gov (United States)

    Oluwayelu, D O; Adebiyi, A I; Ohore, O G; Cadmus, S I B

    2014-12-01

    Rabies is a highly fatal zoonosis that causes severe destruction to the central nervous system and remains underreported in developing countries like Nigeria. The increasing close contact between dogs and their owners or neighbours suggest a need for investigation of the protective level of rabies virus (RABV) antibodies in dogs. Sera from 150 apparently healthy neighbourhood dogs from some peri-urban and rural areas of Ogun and Oyo states, southwestern Nigeria were analyzed for the presence of RABV antibodies using the indirect ELISA technique. These dogs were kept as pets, used for hunting or sold for human consumption. The results showed that none of the dogs had optimal RABV antibody titres, 25 (16.7%) had sub-optimal antibody titres while 125 (83.3%) were negative. Detection of sub-optimal RABV antibody levels in these unvaccinated dogs suggests that they might have been exposed to rabies or rabies-related viruses. Data obtained from interviews conducted revealed that 21.3% of the dog owners were informed about rabies but neglected vaccination while 44.7% were uninformed. We conclude that these dogs lacked protective levels of RABV antibodies and thus constitute a public, health threat. This finding underscores the need for dog anti-rabies vaccination campaigns covering peri-urban and rural areas as well as the promotion of large scale public enlightenment programmes on rabies in Nigeria.

  15. Work-related stress perception and hypertension amongst health workers of a mission hospital in Oyo State, south-western Nigeria

    Directory of Open Access Journals (Sweden)

    Akinwumi O. Owolabi

    2012-04-01

    Objective: This study was a work site cross-sectional descriptive study carried out amongst the health workers at the Baptist Medical Centre Ogbomoso, Oyo State, south-western Nigeria. The aim of the study was to discern the prevalence of perceived work stress and to explore the relationship between perceived work stress and the presence of hypertension. Methods: A total of 324 consenting health workers of the institution were administered the job demand-control questionnaire to assess work stress. A standardised questionnaire was used to collect socio-demographic data and other personal data. Measurements of blood pressure, weight and height were carried out and body mass indices were calculated. Results: More than a quarter (26.2% of the subjects perceived themself as stressed at work. The single largest group of hypertensive subjects was seen amongst subjects with work stress. Conclusion: A significant number of health workers in this study is afflicted by work-related stress and perceived work stress was found to be significantly associated with higher hypertension prevalence.

  16. Activation of eNOS by D-pinitol Induces an Endothelium-Dependent Vasodilatation in Mouse Mesenteric Artery

    Directory of Open Access Journals (Sweden)

    Luciana N. Moreira

    2018-05-01

    Full Text Available D-pinitol is a cyclitol present in several edible plant species and extensively investigated for the treatment of metabolic diseases in humans, as food supplement, and demonstrated protective effects in the cardiovascular system. For these reasons, the present work aimed at investigating the mechanisms involved in the vascular effects of D-pinitol in mouse mesenteric artery. Mesenteric arteries from male C57BL/6 mice were mounted in a wire myograph. Nitrite was measured by the 2,3-diaminonaphthalene (DAN method. Protein expression and phosphorylation were measured by Western blot. The systolic blood pressure (SBP was measured by tail-cuff plethysmography. D-pinitol induced a concentration-dependent vasodilatation in endothelium-intact, but not in endothelium-denuded arteries. Nω-Nitro-L-arginine methyl ester (300 μM abolished the effect of D-pinitol, while 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (ODQ; 10 μM shifted the concentration-response curve to the right. KN-93 (1 μM blunted the vasodilator effect of D-pinitol, but H-89 (0.1 μM did not change it. 1-[2-(Trifluoromethyl phenyl]imidazole (300 μM, indomethacin (10 μM, celecoxib (5 μM, wortmannin (1 μM, ruthenium red (10 μM, tiron (10 μM, MnTMPyP (30 μM, MPP (0.1 μM, PHTPP (0.1 μM, and atropine (1 μM did not change the effect of D-pinitol. D-pinitol increased the concentration of nitrite, which was inhibited by L-NAME and calmidazolium (10 μM. D-pinitol increased the phosphorylation level of eNOS activation site at Ser1177 and reduced the phosphorylation level of its inactivation site at Thr495. In normotensive mice, the intraperitoneal administration of D-pinitol (10 mg/kg induced a significant reduction of the SBP after 30 min. The present results led us to conclude that D-pinitol has an endothelium- and NO-dependent vasodilator effect in mouse mesenteric artery through a mechanism dependent on the activation of eNOS by the calcium-calmodulin complex, which can explain its

  17. Variable effects of maternal and paternal-fetal contribution to the risk for preeclampsia combining GSTP1, eNOS, and LPL gene polymorphisms.

    Science.gov (United States)

    Pappa, Kalliopi I; Roubelakis, Maria; Vlachos, George; Marinopoulos, Spyros; Zissou, Antonia; Anagnou, Nicholas P; Antsaklis, Aris

    2011-04-01

    To evaluate the maternal, paternal, and fetal genotype contribution to preeclampsia. STUDY DESIGN, MATERIALS, AND METHODS: We combined the analysis of polymorphisms of the GSTP1, eNOS, and LPL genes - affecting biotransformation enzymes and endothelial function - in a cohort of 167 preeclamptic and normal control trios (mother, father, and child) comprising a total of 501 samples in the Greek population, never analyzed before by this approach. For the frequency of the GSTP1 Ile(105)/Val(105), the eNOS Glu298Asp and the LPL-93 polymorphisms, statistically significant differences were found between the two groups. However, the transmission rates of the parental alleles to neonates studied by the transmission disequilibrium test, disclosed no increased rate of transmission to preeclampsia children for the variant alleles of Val(105) GSTP1, 298Asp eNOS, and -93G LPL. These novel data, suggest that interaction of all three types of genotypes (mother, father and neonate), reveals no effects on the development of preeclampsia, but provide the impetus for further studies to decipher the individual contribution of each genetic parameter of preeclampsia.

  18. Exercise Training Could Improve Age-Related Changes in Cerebral Blood Flow and Capillary Vascularity through the Upregulation of VEGF and eNOS

    Directory of Open Access Journals (Sweden)

    Sheepsumon Viboolvorakul

    2014-01-01

    Full Text Available This study aimed to investigate the effect of exercise training on age-induced microvascular alterations in the brain. Additionally, the association with the protein levels of vascular endothelial growth factor (VEGF and endothelial nitric oxide synthase (eNOS was also assessed. Male Wistar rats were divided into four groups: sedentary-young (SE-Young, n=5, sedentary aged (SE-Aged, n=8, immersed-aged (IM-Aged, n=5, and exercise trained-aged (ET-Aged, 60 minutes/day and 5 days/week for 8 weeks, n=8 rats. The MAPs of all aged groups, SE-Aged, IM-Aged, and ET-Aged, were significantly higher than that of the SE-Young group. The regional cerebral blood flow (rCBF in the SE-Aged and IM-Aged was significantly decreased as compared to SE-Young groups. However, rCBF of ET-Aged group was significantly higher than that in the IM-Aged group (P<0.05. Moreover, the percentage of capillary vascularity (%CV and the levels of VEGF and eNOS in the ET-Aged group were significantly increased compared to the IM-Aged group (P<0.05. These results imply that exercise training could improve age-induced microvascular changes and hypoperfusion closely associated with the upregulation of VEGF and eNOS.

  19. Marine Compound Catunaregin Inhibits Angiogenesis through the Modulation of Phosphorylation of Akt and eNOS in vivo and in vitro

    Directory of Open Access Journals (Sweden)

    Jun-Xiu Liu

    2014-05-01

    Full Text Available Angiogenesis is the formation of blood vessels from pre-existing vasculature. Excessive or uncontrolled angiogenesis is a major contributor to many pathological conditions whereas inhibition of aberrant angiogenesis is beneficial to patients with pathological angiogenesis. Catunaregin is a core of novel marine compound isolated from mangrove associate. The potential anti-angiogenesis of catunaregin was investigated in human umbilical vein endothelial cells (HUVECs and zebrafish. HUVECs were treated with different concentrations of catunaregin in the presence or absence of VEGF. The angiogenic phenotypes including cell invasion cell migration and tube formation were evaluated following catunaregin treatment in HUVECs. The possible involvement of AKT, eNOS and ERK1/2 in catunaregin-induced anti-angiogenesis was explored using Western blotting. The anti-angiogenesis of catunaregin was further tested in the zebrafish embryo neovascularization and caudal fin regeneration assays. We found that catunaregin dose-dependently inhibited angiogenesis in both HUVECs and zebrafish embryo neovascularization and zebrafish caudal fin regeneration assays. In addition, catunaregin significantly decreased the phosphorylation of Akt and eNOS, but not the phosphorylation of ERK1/2. The present work demonstrates that catunaregin exerts the anti-angiogenic activity at least in part through the regulation of the Akt and eNOS signaling pathways.

  20. Expression profiles of eNOS, iNOS and microRNA-27b in the corpus cavernosum of rats submitted to chronic alcoholism and Diabetes mellitus.

    Science.gov (United States)

    Cunha, Joao Paulo da; Lizarte, Fermino Sanches; Novais, Paulo Cezar; Gattas, Daniela; Carvalho, Camila Albuquerque Mello de; Tirapelli, Daniela Pretti da Cunha; Molina, Carlos Augusto Fernandes; Tirapelli, Luis Fernando; Tucci, Silvio

    2017-01-01

    To evaluate the expression of endothelial and inducible NOS in addition to the miRNA-27b in the corpus cavernosum and peripheral blood of healthy rats, diabetic rats, alcoholic rats and rats with both pathologies. Forty eight Wistar rats were divided into four groups: control (C), alcoholic (A), diabetic (D) and alcoholic-diabetic (AD). Samples of the corpus cavernosum were prepared to study protein expressions of eNOS and iNOS by immunohistochemistry and expression of miRNA-27b in the corpus cavernosum and peripheral blood. Immunohistochemistry for eNOS and iNOS showed an increase in cavernosal smooth muscle cells in the alcoholic, diabetic and alcoholic-diabetic groups when compared with the control group. Similarly, the mRNA levels for eNOS were increased in cavernosal smooth muscle (CSM) in the alcoholic, diabetic and alcoholic-diabetic groups and miRNA-27b were decreased in CSM in the alcoholic, diabetic and alcoholic-diabetic groups. The major new finding of our study was an impairment of relaxation of cavernosal smooth muscle in alcoholic, diabetic, and alcoholic-diabetic rats that involved a decrease in the nitric oxide pathway by endothelium-dependent mechanisms accompanied by a change in the corpus cavernosum contractile sensitivity.

  1. Glycolipids from spinach suppress LPS-induced vascular inflammation through eNOS and NK-κB signaling.

    Science.gov (United States)

    Ishii, Masakazu; Nakahara, Tatsuo; Araho, Daisuke; Murakami, Juri; Nishimura, Masahiro

    2017-07-01

    Glycolipids are the major constituent of the thylakoid membrane of higher plants and have a variety of biological and pharmacological activities. However, anti-inflammatory effects of glycolipids on vascular endothelial cells have not been elucidated. Here, we investigated the effect of glycolipids extracted from spinach on lipopolysaccharides (LPS)-induced endothelial inflammation and evaluated the underlying molecular mechanisms. Treatment with glycolipids from spinach had no cytotoxic effects on cultured human umbilical vein endothelial cells (HUVECs) and significantly blocked the expression of LPS-induced interleukin (IL)-6, monocyte chemoattractant protein-1 (MCP-1), vascular cell adhesion molecule-1 (VCAM-1), and intracellular adhesion molecule-1 (ICAM-1) in them. Glycolipids treatment also effectively suppressed monocyte adhesion to HUVECs. Treatment with glycolipids inhibited LPS-induced NF-κB phosphorylation and nuclear translocation. In addition, glycolipids treatment significantly promoted endothelial nitric oxide synthase (eNOS) activation and nitric oxide (NO) production in HUVECs. Furthermore, glycolipids treatment blocked LPS-induced inducible NOS (iNOS) expression in HUVECs. Pretreatment with a NOS inhibitor attenuated glycolipids-induced suppression of NF-κB activation and adhesion molecule expression, and abolished the glycolipids-mediated suppression of monocyte adhesion to HUVECs. These results indicate that glycolipids suppress LPS-induced vascular inflammation through attenuation of the NF-κB pathway by increasing NO production in endothelial cells. These findings suggest that glycolipids from spinach may have a potential therapeutic use for inflammatory vascular diseases. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  2. The effect of high protein diet and exercise on irisin, eNOS, and iNOS expressions in kidney.

    Science.gov (United States)

    Tastekin, Ebru; Palabiyik, Orkide; Ulucam, Enis; Uzgur, Selda; Karaca, Aziz; Vardar, Selma Arzu; Yilmaz, Ali; Aydogdu, Nurettin

    2016-08-01

    Long-term effects of high protein diets (HPDs) on kidneys are still not sufficiently studied. Irisin which increases oxygen consumption and thermogenesis in white fat cells was shown in skeletal muscles and many tissues. Nitric oxide synthases (NOS) are a family of enzymes catalyzing the production of nitric oxide (NO) from L-arginine. We aimed to investigate the effects of HPD, irisin and NO expression in kidney and relation of them with exercise and among themselves. Animals were grouped as control, exercise, HPD and exercise combined with HPD (exercise-HPD). Rats were kept on a HPD for 5 weeks and an exercise program was given them as 5 exercise and 2 rest days per week exercising on a treadmill with increasing speed and angle. In our study, while HPD group had similar total antioxidant capacity (TAC) levels with control group, exercise and exercise-HPD groups had lower levels (p highly selective and quite clear in this study. Effects of exercise and HPD on kidney should be evaluated with different exercise protocols and contents of the diet. İrisin, eNOS, and iNOS staining localizations should be supported with various research studies.

  3. `Joint Research and Development of Industrial Technology,` an international research collaboration for fiscal 1997. Utilization of 3D-woven C/C composite materials to machine components; 1997 nendo kokusai kenkyu kyoryoku jigyo `sangyo kiban gijutsu kyodo kenkyu kaihatsu`. Sanjigen ori C/C composite zairyo no kikai buhin eno oyo ni kansuru kenkyu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    A polygonal mirror in a printer and the main shaft of a high-speed milling machine are used as models for the development of technology for applying C/C (carbon/carbon) composite materials to machine components that are required to turn at high speeds. Various C/C composites are tested for flexural strength and thermal expansion for the designing and manufacturing of C/C composites for the polygonal mirror and main shaft. The first coating on the C/C composite is deposited by laser/plasma hybrid spraying, and is a Mo coating. A spraying robot is experimentally built for homogeneous coating. In the case of polygonal mirror, an Al coating is deposited further by the gas-deposition method. The polygonal mirror proves excellent in both dimension and reflectance, and attains the target speed of 45,000rpm. In the case of milling machine main shaft, however, it is not strong enough to withstand 40,000rpm although it is a success from a viewpoint of coating technology and manufacturing technology. 15 refs., 33 figs., 13 tabs.

  4. Research on PV system application on residences. Part 1. Report on the systems and PV measurement results of an experimental passive solar house; Taiyoko hatsuden system no jutaku eno oyo ni kansuru kenkyu. 1. Taisho tatemono taiyo to taiyoko hatsuden system keisoku kekka

    Energy Technology Data Exchange (ETDEWEB)

    Ishihara, O.; Sakai, K.; Hirakawa, M. [Kumamoto University, Kumamoto (Japan). Faculty of Engineering

    1997-11-25

    System of the house is outlined, and warming performance and photovoltaic power generation system energy performance are taken up. It is a one-storied meeting hall situated in an apartment area, whose heat loss factor is 2.59kcal/m2hdegC. Ninety hybrid solar cells provided with circulating air heat collectors are installed on the east-side of the roof, interconnected to the commercial power system. In the daytime in summer, the house is fully insulated from solar radiation, with the room temperature kept a little lower than the open air temperature. The range of daily change in the room temperature is narrow, providing a comfortable residential space. When the windows are opened in the evening, cool air comes into the room to replace the warm air inside, reducing the difference in temperature between the inside and outside of the room. In winter, insolation time is short on the east side of the roof which finds itself out of the sun. Under the circumstances, the system outputs but a little and the quantity sold is quite small in winter. But, in summer, sale of power can be practicable, thanks to exposure to sufficient sunshine. The inverter rated at 3.5kW attains a 90% or higher operating rate in the presence of an input of power of 0.5kW or more. 4 refs., 10 figs.

  5. FY 1995 development of fluorinated hydriding alloys with multi functional and functionally-graded surface and their application to energy conversion devices; 1995 nendo keishagata fukugo kino wo hyomen ni motsu suiso kyuzo gokin no kaihatsu to energy henkan gijutsu eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    The project is the extended researches of a fluorination technique invented by the project leader (Suda) for improving the surface properties and characteristics of conventional hydriding alloys from the following viewpoints; (1) To investigate the roles of fluorinated surface during hydrogen uptake both in the gas-solid and the electrochemical reactions. (2) To elucidate the factors which increase the protective nature of the surface. (3) To develop a material design procedure for synthesizing thin layer of functionally graded surface which is composed of metallic Ni and the fluoride compound. (1) An advanced fluorination technique was developed to incorporate metallic Ni in the surface fluoride layer. (2) Metallic Ni was successfully distributed in a functionally graded manner in the Surface fluoride layer. (3) Through the technique developed, the following properties and characteristics were successfully donated in the fluorinated hydriding alloys such as AB{sub 5}, AB{sub 2}, and AB; (3-1)Surface oxides which act as the resistant layer to the hydrogen up take was completely eliminated to result in the enhancement of the initial activation characteristics. (3-2) Hydrogen selectivity and permeability was greatly improved. (3-3) Surface protective nature against the impurity gases and contaminants was significantly improved. (3-4) Initial activation characteristics both in the gas-solid and the electrochemical reactions were distinguishably improved. (3-5) Fluorinated surface was found to function as the catalyst for a methanation reaction between the CO{sub 2} gas adsorbed over the fluorinated surface and the monatomic hydrogen absorbed in the metal lattice of the crystalline structure of the hydriding alloys. (4) A technique was developed for increasing the specific surface area and decreasing the specific surface diameter of the fluorinated hydriding alloy articles. (NEDO)

  6. Acoustic excitation of diffusion flames with coherent structure in a plane shear layer. ; Application of active combustion control to two-dimensional phase-locked arranging measurements. Soshiki kozo wo tomonau heimen sendai kakusan kaen no onkyo reiki. ; Nijigen iso heikin bunpu sokutei eno active nensho seigyo no oyo

    Energy Technology Data Exchange (ETDEWEB)

    Ishino, Y.; Kojima, T.; Oiwa, N.; Yamaguchi, S. (Nagoya Institute of Technology, Nagoya (Japan))

    1993-11-25

    The acoustic excitation of a plane diffusion flame enhances the periodicity of organized eddy controlled combustion. In this study, to clarify an effectiveness of application of active combustion control, phase characteristics of the excited eddy flames with high periodicity have been examined. A computer-aided phase-locked averaging method was employed to obtain graphical two-dimensional contour maps of the instantaneous profiles of temperature and CH emission. Both maps consisting of eight consecutive phases indicated clearly not only the periodic behavior of the organized eddy flame, but also the gas dynamic properties peculiar to those flames with coherent structure. In addition, the profiles of local contribution of the sound field to the combustion process were examined by calculating the two-dimensional distribution of the local Rayleigh index. Calculation results of the two-dimensional distribution of the local Rayleigh index indicated that the organized eddy flames have high sensitivity to sound, and play an important role in an interaction of sound and flame. 6 refs., 9 figs.

  7. Development of velocity interferometer and its application to piston motion measurement in a compression tube of freepiston shock tube; Sokudo kanshokei no kaihatsu to sono jiyu piston shogekihakan no asshuku kannai no piston undo no keisoku eno oyo ni kansuru kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    Koremoto, K.; Hashimoto, T. [Tohoku University, Sendai (Japan); Takayama, K. [Tohoku University, Sendai (Japan). Inst. of Fluid Science; Ito, K [National Aerospace Laboratory, Tokyo (Japan)

    1999-10-25

    A free piston shock tunnel has been intensively used as a hypersonic flow ground test facility and its characteristics depend sensitively upon the piston motion in its compression tube. The continuous measurement of the piston motion in its compression tube was studied in an analogue facility in which a piston motion in a 50mm dia. and 2000mm long compression tube was measured continuously and accurately from its start to the collision with bumper section. To achieve it a velocity interferometer was developed particularly to measure the piston speed in it. Then piston motions were successfully measured and result agreed very well with numerical result. (author)

  8. Compact digital NTSC TV signal transmission system using SM optical fibers and its application to operating status monitoring for laser cutting machine; Digital gazo shingo no kan`igata hikari fiber denso system to sono laser cutter no dosa jotai kanshi eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Asada, H. [NEC Shizuoka, Ltd., Shizuoka (Japan); Rabou, N. [University of Helwan, (Egypt); Ikeda, H.; Shimodaira, Y.; Yoshida, H. [Shizuoka University, Shizuoka (Japan)

    1998-02-01

    This paper describes a compact bandwidth-compressed digital NTSC picture code transmission system in which circuit configurations are simplified and made inexpensive. The bandwidth of digital NTSC picture codes is compressed in accordance with subjective evaluation, and so the sampling rate is set at 8.13 MHz (2.28 times fsc) and the quantizing level at 5 bits. The frame bits for detecting the frames of picture elements me generated by alternately generating 1 and 0 when the frames are specified. The proposed system is constructed using edge- emitting LED`s (ELED`s) and single- mode (SM) fibers for transmitting digital NTSC picture codes w m to easily distribute video signals from a video camera to video monitors. The transmitter was 80 times 100mm in size, 120 g in weight, and 1000mw in power dissipation. The receiver was 55 times 120 mm in size, 100g in weight, and 800mw in power dissipation. Using the compact bandwidth-compressed digital NTSC picture code transmission system a shot of the working pice in the laser cutting machine, as an example, was satisfactorily transmitted via SM optical fibers without noses. 18 refs., 12 figs., 2 tabs.

  9. Fiscal 1999 achievement report on regional consortium research and development project. Regional consortium on energy research in its 3rd year (Research and development of novel method for manufacturing recycling-compatible functional thin film and its application to coloring of glass); 1999 nendo recycle ni tekishita kinosei usumaku no shinki seizoho to chakushoku glass eno oyo ni kansuru kenkyu kaihatsi seika hokokusho. 3

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    A thin film is developed which adds new functions to the surface of glass materials. The method is applied to the coloring of glass for the enhancement of recyclability (for example, by coating colorless glass bottles with colorful thin film) and to the functionalization of glass. Studies are conducted about the assessment of coloring-capable thin film basic characteristics, manufacture of liquids for application, and the manufacture of photosensitive gel thin film using chemically modified metal alkoxides. It is found that use of functional pigments reduces the transmissivity of ultraviolet and infrared rays. A method for manufacturing coloring liquids for application to glass bottles and a method of improving film durability using a 3,2-functional silane are established. Ultrafine gold/cuprous oxide powder, azobenzen based pigments, etc., are deposited on porous glass for the formation of a photoresponsive film. Conditions for color application to round glass bottles are optimized by use of an air spray device. Film exfoliation during colored glass bottle transportation is lessoned to a practically acceptable level by modifying the carton pack configuration. A large roll-type applicator is operated to successfully form a homogenous coating on a 1.8m times 1m glass plate. Double glazing capable of light modulation is also manufactured. (NEDO)

  10. Fiscal 1998 achievement report on regional consortium research and development project. Venture business raising type regional consortium - small business creating base type (Control of gene expression by ligands for nuclear receptors and its application to medicine manufacture - 2nd year); 1998 nendo kakunai juyotai ligand ni yoru iden joho hatsugen no seigyo to iyaku seizo process eno oyo seika hokokusho. 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    Studies are made about ascochlorin and its derivatives which are expected to be effective in the treatment and prevention of lifestyle diseases such as arteriosclerosis, diabetes, hypertension, etc. The current goal is to definitely prove at the cell culture stage that ascochlorin and its derivatives act as ligands for nuclear receptors. As the result of the effort to prove their activation of nuclear receptors, it is clarified that they activate not only PPARr, which is the initial target of the research, but also PPARa, PXR, and ER. A computer simulation of interaction between ascochlorin derivatives and PPARr is conducted, and now it is predicted that the helix 10 cubic structure is transformed so that co-activators may connect to the structure. It is also found that AS-6 inhibits almost completely the appearance of type II diabetes in the db/db mouse lacking leptin receptors and type I diabetes in the NOD (non-obese diabetes) mouse. (NEDO)

  11. Achievement report for fiscal 1998. Research and development on a new manufacturing method for functional thin films suitable for recycling, and their application to colored glasses (the second year); 1998 nendo seika hokokusho. Recycle ni tekishita kinosei usumaku no shinki seizoho to chakushoku glass eno oyo ni kansuru kenkyu kaihatsu (dai 2 nendo)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    A new thin film manufacturing method is established to add a function to glass material surface, as a new material technology which harmonizes with global environment, and is suitable for resource re-utilization and energy conservation. It is intended to develop a leading technology to promote recycling of colored glasses by applying this technical method to colored glasses. Fiscal 1998 has implemented subsequently to fiscal 1997 the following subjects in the three research items composed of a new manufacturing method of functional thin films, application of the functional thin films to colored glasses, and the comprehensive investigative studies: establishment of an industrial manufacturing method for color coating liquid and evaluation of basic characteristics of the colored functional thin films, optimization of element technology for photo-sensitive gel films by means of chemically modifying metallic alkoxide, tests of forming films on glass bottles and plate glasses by using a coating machine installed in fiscal 1997, design and prototype fabrication of a new demonstration coating machine, and analysis on thermal decomposition of the colored thin films. Optimization was performed on the element technology for manufacturing sol-gel functional thin films, and a survey was carried out on recycling systems of colored glasses adopted in Europe. (NEDO)

  12. Social support seeking and self-efficacy-building strategies in enhancing the emotional well-being of informal HIV/AIDS caregivers in Ibadan, Oyo state, Nigeria.

    Science.gov (United States)

    Okeke, Bernedette Okwuchukwu

    2016-01-01

    This study examined the relative efficacy of social support seeking (SSS) and self-efficacy building (SEB) in the management of emotional well-being of caregivers of people suffering from HIV/AIDS. It was based at the United States President's Emergency Plan for AIDS Relief (PEPFAR) center in the University College Hospital, Ibadan, Oyo state, being the first and the largest teaching hospital in Nigeria. A 3 × 2 factorial design consisting of treatment and a control group was used. The columns have two levels of gender being male and female caregivers. One-hundred and sixty-five (165) caregivers who were taking care of people that are suffering from HIV/AIDS were purposively selected and randomly assigned to the treatment groups and control. The treatment was carried out for a period of eight weeks. Two null hypotheses were tested, both at .05 levels of significance. Data were collected with the use of standardized intruments rating scale; social support scale, general self-efficacy scale and emotional well-being scale. ANCOVA was used to establish significant treatment effects with the pretest as covariate. Even though SSS and SEB were both found to be effective in enhancing the emotional well-being of informal caregivers in this study when compared to the controls, SSS was significantly more effective than SEB in achieving this goal. Since the HIV/AIDS patients cannot be adequately cared for in the hospital settings due to severe shortages of material, personnel and time, serious efforts should be made by the three levels of the health care system viz: the primary, secondary and tertiary health care systems, to encourage the employment of the psychological management of caregivers of people suffering from HIV/AIDS. Also, the psychologists, clinical psychologists and the significant others should be encouraged to employ this psychological management in the care of HIV/AIDS informal caregivers.

  13. TECHNICAL EFFICIENCY OF PRODUCTION OF QUALITY PROTEIN MAIZE BETWEEN ADOPTERS AND NON-ADOPTERS, AND THE DETERMINANTS IN OYO STATE, NIGERIA

    Directory of Open Access Journals (Sweden)

    Abiodun Elijah OBAYELU

    2016-11-01

    Full Text Available This study determined the technical efficiency (TE of production of Quality Protein Maize (QPM and the effect on the adoption of QPM in Oyo State, Nigeria. QPM is an improved maize variety developed to reduce protein deficiency problems. A total of 100 maize farmers were sampled through a two-stage sampling procedure. Stochastic frontier approach using maximum likelihood estimation (MLE was used to analyse the TE in the production of QPM, while probit regression was used to determine the effect of TE and other socioeconomic characteristics of the respondents on the adoption of QPM. The results revealed a mean TE of 0.89 and 0.78 for adopters and non-adopters of QPM respectively. This implied that adopters of QPM are more technically efficient than the non-adopters. Quantity of seed planted and fertilizer directly and significantly affected the TE of QPM while gross margin of maize farmers and income from other sources (at P<0.05, the level of education of farmers and QPM farm size (P<0.01 have significant and a negative effects on technical inefficiency from the results of the Tobit regression. The age (P<0.05 of the farmer has direct effect on technical inefficiency. In conclusion, TE, level of output, information availability on QPM and early maturity were significant determinants of QPM rather than the gross margin of production. Farmers decide to adopt QPM technology because of the high level of technical efficiency in the production of this variety. Their output from QPM can be increased by 11 percent, while the non-adopters can increase their maize output by 22 percent using the available technology.

  14. Prevalence and antibiotic susceptibility profiles of Listeria monocytogenes contamination of chicken flocks and meat in Oyo State, south-western Nigeria: Public health implications.

    Science.gov (United States)

    Ishola, O O; Mosugu, J I; Adesokan, H K

    2016-09-01

    Food contamination with Listeria monocytogenes is on the increase posing threats to public health with growing trends in food products recalls due to suspected Listeria contamination. We conducted a cross-sectional study to determine the prevalence and antibiotic susceptibility profiles of Listeria monocytogenes (Lm) among 71 randomly selected poultry farms in Oyo State, Nigeria. A total of 450 samples comprising cloacal swabs (426) and randomly selected dressed chicken meat (24) were cultured for Lm isolation using BrillianceTM Selective Listeria Agar with antibiotics and microbial load count with Nutrient Agar. Further identification was done using microscopic, biochemical characterization and antibiotic sensitivity tests. Data were analysed using bivariate analysis and student t-test. An overall prevalence of 91.8% Lm contamination was obtained comprising 91.5% (390/426) in cloacal swabs and 95.8% (23/24) in meat. The prevalence of Lm in cloacal samples was significantly associated with poultry type (p = 0.008) and breed (p = 0.000. In addition, all the flocks had at least one positive sample yielding 100% flock prevalence. Antibiotic sensitivity test revealed that most of the isolates were resistant to common antibiotics like Ampicillin-cloxacillin and cefuroxime. The results revealed a high level of contamination with Lm in the poultry flock and meat and the observed resistance to most common antibiotics has implications for future disease control as well as public health. There is need to step up routine screening of food animal products for Listeria contamination as well as measures towards reducing such contaminations.

  15. MiR-21 is induced in endothelial cells by shear stress and modulates apoptosis and eNOS activity

    Energy Technology Data Exchange (ETDEWEB)

    Weber, Martina; Baker, Meredith B.; Moore, Jeffrey P. [Division of Cardiology, Emory University, 1639 Pierce Drive, WMB 319, Atlanta, GA 30322 (United States); Searles, Charles D., E-mail: csearle@emory.edu [Division of Cardiology, Emory University, 1639 Pierce Drive, WMB 319, Atlanta, GA 30322 (United States); Atlanta Veterans Administration Medical Center, 1670 Clarimont Road, Decatur, GA 30033 (United States)

    2010-03-19

    Mechanical forces associated with blood flow play an important role in regulating vascular signaling and gene expression in endothelial cells (ECs). MicroRNAs (miRNAs) are a class of noncoding RNAs that posttranscriptionally regulate the expression of genes involved in diverse cell functions, including differentiation, growth, proliferation, and apoptosis. miRNAs are known to have an important role in modulating EC biology, but their expression and functions in cells subjected to shear stress conditions are unknown. We sought to determine the miRNA expression profile in human ECs subjected to unidirectional shear stress and define the role of miR-21 in shear stress-induced changes in EC function. TLDA array and qRT-PCR analysis performed on HUVECs exposed to prolonged unidirectional shear stress (USS, 24 h, 15 dynes/cm{sup 2}) identified 13 miRNAs whose expression was significantly upregulated (p < 0.05). The miRNA with the greatest change was miR-21; it was increased 5.2-fold (p = 0.002) in USS-treated versus control cells. Western analysis demonstrated that PTEN, a known target of miR-21, was downregulated in HUVECs exposed to USS or transfected with pre-miR-21. Importantly, HUVECs overexpressing miR-21 had decreased apoptosis and increased eNOS phosphorylation and nitric oxide (NO{sup {center_dot}}) production. These data demonstrate that shear stress forces regulate the expression of miRNAs in ECs, and that miR-21 influences endothelial biology by decreasing apoptosis and activating the NO{sup {center_dot}} pathway. These studies advance our understanding of the mechanisms by which shear stress forces modulate vascular homeostasis.

  16. Ibuprofen arginate retains eNOS substrate activity and reverses endothelial dysfunction: implications for the COX-2/ADMA axis.

    Science.gov (United States)

    Kirkby, Nicholas S; Tesfai, Abel; Ahmetaj-Shala, Blerina; Gashaw, Hime H; Sampaio, Walkyria; Etelvino, Gisele; Leão, Nádia Miricéia; Santos, Robson A; Mitchell, Jane A

    2016-12-01

    Nonsteroidal antiinflammatory drugs, including ibuprofen, are among the most commonly used medications and produce their antiinflammatory effects by blocking cyclooxygenase (COX)-2. Their use is associated with increased risk of heart attacks caused by blocking COX-2 in the vasculature and/or kidney, with our recent work implicating the endogenous NOS inhibitor asymmetric dimethylarginine (ADMA), a cardiotoxic hormone whose effects can be prevented by l-arginine. The ibuprofen salt ibuprofen arginate (Spididol) was created to increase solubility but we suggest that it could also augment the NO pathway through codelivery of arginine. Here we investigated the idea that ibuprofen arginate can act to simultaneously inhibit COX-2 and preserve the NO pathway. Ibuprofen arginate functioned similarly to ibuprofen sodium for inhibition of mouse/human COX-2, but only ibuprofen arginate served as a substrate for NOS. Ibuprofen arginate but not ibuprofen sodium also reversed the inhibitory effects of ADMA and N G -nitro-l-arginine methyl ester on inducible NOS (macrophages) and endothelial NOS in vitro (aorta) and in vivo (blood pressure). These observations show that ibuprofen arginate provides, in one preparation, a COX-2 inhibitor and NOS substrate that could act to negate the harmful cardiovascular consequences mediated by blocking renal COX-2 and increased ADMA. While remarkably simple, our findings are potentially game-changing in the nonsteroidal antiinflammatory drug arena.-Kirkby, N. S., Tesfai, A., Ahmetaj-Shala, B., Gashaw, H. H., Sampaio, W., Etelvino, G., Leão, N. M., Santos, R. A., Mitchell, J. A. Ibuprofen arginate retains eNOS substrate activity and reverses endothelial dysfunction: implications for the COX-2/ADMA axis. © The Author(s).

  17. Arginase up-regulation and eNOS uncoupling contribute to impaired endothelium-dependent vasodilation in a rat model of intrauterine growth restriction.

    Science.gov (United States)

    Grandvuillemin, Isabelle; Buffat, Christophe; Boubred, Farid; Lamy, Edouard; Fromonot, Julien; Charpiot, Philippe; Simoncini, Stephanie; Sabatier, Florence; Dignat-George, Françoise; Peyter, Anne-Christine; Simeoni, Umberto; Yzydorczyk, Catherine

    2018-05-09

    Individuals born after intrauterine growth restriction (IUGR) are at increased risk of developing cardiovascular diseases in adulthood, notably hypertension (HTN). Alterations in the vascular system, particularly impaired endothelium-dependent vasodilation, may play an important role in long-term effects of IUGR. Whether such vascular dysfunction precedes HTN has not been fully established in individuals born after IUGR. Moreover, the intimate mechanisms of altered endothelium-dependent vasodilation remain incompletely elucidated. We therefore investigated, using a rat model of IUGR, whether impaired endothelium-dependent relaxation precedes the development of HTN and whether key components of the L-Arginine-nitric oxide (NO) pathway are involved in its pathogenesis. Pregnant rats were fed with a control (CTRL, 23% casein) or low-protein diet (LP, 9% casein) to induce IUGR. Systolic blood pressure (SBP) was measured by tail-cuff plethysmography in 5- and 8-week-old male offspring. Aortic rings were isolated to investigate relaxation to acetylcholine, NO production, eNOS protein content, arginase activity, and superoxide anion production. SBP was not different at 5 weeks, but significantly increased in 8-week-old LP vs. CRTL offspring. In 5-week-old LP vs. CRTL males, endothelium-dependent vasorelaxation was significantly impaired, but restored by pre-incubation with L-Arginine or the arginase inhibitor BEC; NO production was significantly reduced, but restored by L-Arginine pretreatment; total eNOS protein, dimer/monomer ratio, and arginase activity were significantly increased; superoxide anion production was significantly enhanced, but normalized by pretreatment with the NOS inhibitor L-NNA. In this model, IUGR leads to early-impaired endothelium-dependent vasorelaxation, resulting from arginase up-regulation and eNOS uncoupling, which precedes the development of HTN.

  18. Enhanced estradiol-induced vasorelaxation in aortas from type 2 diabetic mice may reflect a compensatory role of p38 MAPK-mediated eNOS activation.

    Science.gov (United States)

    Taguchi, Kumiko; Morishige, Akitaka; Matsumoto, Takayuki; Kamata, Katsuo; Kobayashi, Tsuneo

    2012-08-01

    Cardiovascular problems are a major cause of morbidity and mortality, mainly due to coronary artery disease and atherosclerosis, in type 2 diabetes mellitus. However, female gender is a protective factor in the development of, for example, atherosclerosis and hypertension. One of the female hormones, 17β-estradiol (E2), is known to protect against the cardiovascular injury resulting from endothelial dysfunction, but the mechanism by which it does so remains unknown. Our hypothesis was that E2-mediated activation of Akt and mitogen-activated protein kinase (MAPK), and the subsequent endothelial NO synthase (eNOS) phosphorylation, might protect the aorta in diabetic mellitus. The experimental type 2 diabetic model we employed to test that hypothesis (female mice given streptozotocin and nicotinamide) is here termed fDM. In fDM aortas, we examined the E2-induced relaxation response and the associated protein activities. In control (age-matched, nondiabetic) aortas, E2 induced a vascular relaxation response that was mediated via Akt/eNOS and mitogen-activated/ERK-activating kinase (MEK)/eNOS pathways. In fDM aortas (vs. control aortas), (a) the E2-induced relaxation was enhanced, (b) the mediation of the response was different (via Akt/eNOS and p38 MAPK/eNOS pathways), and (c) E2 stimulation increased p38 MAPK and eNOS phosphorylations, decreased MEK phosphorylation, but did not alter estrogen receptor activity. We infer that at least in fDM aortas, E2 has beneficial effects (enhanced vascular relaxation and protection) that are mediated through Akt activation and (compensating for reduced MEK activation) p38 MAPK activation, leading to enhanced eNOS phosphorylation.

  19. Influence of eNOS gene 4a/bVNTR polymorphism on development of endothelial dysfunction and respiratory system disorders in children - residents of radioactively contaminated areas

    International Nuclear Information System (INIS)

    Stepanova, Je.Yi.; Kolpakov, Yi.Je.; Zigalo, V.M.; And Others

    2015-01-01

    Total of 184 children were examined to determine the possible associative links between eNOS gene intron 4m polymorphism and indices characterizing the functional state of the endothelium and the bronchopulmonary system. Of them the main group of children consisted of 135 childrenresidents of radioactively contaminated areas, the control group - of 49 healthy children who lived in ''clean'' regions by the radioactive con tamination and were not belonging to victims of the Chernobyl accident contingents. The molecular genetic study determining the eNOS gene intron 4 polymorphism was performed. Children of the main group did not differ from that of control and literature data by the frequency of geno types 4a/b and eNOS gene allele polymorphism. An increase in the duration of circulation restoration up to the ini tial level after occlusion test was noted in children of the main group with genotype 4a/4b comparing to children with genotype 4b/4b ; a decrease in the nitrite content was observed in blood serum. The integral indices of elastic ity and tensility of the lung tissue, respiratory permeability were decreased; the signs of bronchospasm were record ed 1.5 times more often. These adverse effects were associated with the presence of genotype allele 4a , the signs of endothelial dysfunction and the level of the incorporated 137 Cs. More pronounced changes in vascular endothelial reaction to occlusion and the significant decrease of serum nitrite level in allele 4a carriers, especially in children who live in adverse ecological conditions, give the right to include them into the risk group for the development of endothelial dysfunction, and to conside pulmonary dysfunction as one of its manifestations

  20. Estrogen and phytoestrogens: Effect on eNOS expression and in vitro vasodilation in cerebral arteries in ovariectomized Watanabe heritable hyperlipidemic rabbits

    DEFF Research Database (Denmark)

    Lund, Claus O.; Mortensen, Alicja; Nilas, Lisbeth

    2007-01-01

    Objectives: To evaluate the effect of estrogen replacement therapy or soy isoflavones supplement on endothelium-dependent relaxation in vitro and gene expression of endothelial nitric oxide synthase (eNOS) in cerebral arteries in a rabbit model of human hypercholesterolemia. Study design: Thirty...... cholesterol was significantly higher at termination in the SoyLife(R) group (P lipoprotein (LDL) cholesterol was comparable in all treatment groups. Neither treatment influenced the endothelium-dependent responses to carbamylcholine chloride or L-NAME or the endothelium...

  1. Influencia del fenómeno ENOS (El Niño y La Niña) en la disponibilidad de grados-día

    OpenAIRE

    Lozada García, Beatriz; Prela, Angélica; Sentelhas, Paulo

    2004-01-01

    Se evaluó la influencia del fenómeno ENOS (El Niño y La Niña) sobre la disponibilidad de calor, en 8 localidades, ubicadas en la región centro-occidental de Venezuela, utilizando concepto de grados-día (GD). Los cambios de la temperatura, representados por las variaciones en los GD, afectarían directamente el ciclo fenológico los cultivos, generando un incremento o reducción en función de desvíos positivos o negativos, respectivamente. Los GD estimados fueron agrupados según el evento predomi...

  2. Effects of a multi-level intervention on the pattern of physical activity among in-school adolescents in Oyo state Nigeria: a cluster randomised trial

    Directory of Open Access Journals (Sweden)

    Mojisola Morenike Oluwasanu

    2017-10-01

    Full Text Available Abstract Background Physical inactivity contributes to the global burden of non-communicable diseases. The pattern of physical activity in adulthood are often established during adolescence and sedentary behaviours in the early years could influence the development of diseases later in life. Studies on physical activity in Nigeria have focused largely on individual behaviours and the effects of school-based interventions have not been well investigated. The aim of the proposed study is to identify factors influencing; and evaluate the effects of a multi-level intervention on the physical activity behaviours of in-school adolescents in Oyo state, Nigeria. Methods The study will adopt a cluster randomised controlled trial design and schools will serve as the unit of randomisation. The sample size is 1000 in-school adolescents aged 10–19 years. The study will be guided by the socio-ecological model and theory of reasoned action and baseline data will be obtained through a mixed methods approach comprising a cross sectional survey to document the self-reported physical activity levels coupled with objectively measured physical activity levels using pedometers for a subset of the sample. Other measurements including weight, height, waist and hip circumferences, fitness level using the 20-m shuttle run test (20-mSRT and blood pressure will be obtained. The schools’ built environment and policy support for physical activity will be assessed using structured questionnaires coupled with key informant interviews and focus group discussions with the school authorities. Baseline findings will guide the design and implementation of a 12-week multi-level intervention. The primary outcome measures are self–reported and 7-day objectively measured physical activity. Other secondary outcome measures are body-mass-index for age, waist-to-hip ratio, cardioresiratory fitness and blood pressure. The association between behavioural factors and physical activity

  3. Relationship of the MTHFD1 (rs2236225, eNOS (rs1799983, CBS (rs2850144 and ACE (rs4343 gene polymorphisms in a population of Iranian pediatric patients with congenital heart defects

    Directory of Open Access Journals (Sweden)

    Mehri Khatami

    2017-09-01

    Full Text Available Congenital heart defects are structural cardiovascular malformations that arise from abnormal formation of the heart or major blood vessels during the fetal period. To investigate the association of 4 single nucleotide polymorphisms (SNPs in the MTHFD1, eNOS, CBS and ACE genes, we evaluated their relationship with CHD in Iranian patients. In this case–control study, a total of 102 children with CHD and 98 control children were enrolled. Four SNPs including MTHFD1 G1958A, eNOS G894T, CBS C-4673G and ACE A2350G were genotyped by PCR-SSCP, Multiplex ARMS PCR and PCR-RFLP methods and confirmed by direct sequencing. We genotyped 102 patients and 98 controls for four polymorphisms by statistically analysis. There were three SNPs including MTHFD1 G1958A, eNOS G894T and ACE A2350G which might increase the risk of CHD, but CBS C-4673G was not significantly different between patients and controls. (P = 0.017, P = 0.048, P = 0.025 and P = 0.081 respectively. The allele frequencies of three SNPs for MTHFD1 G1958A, eNOS G894T and ACE A2350G in CHD are higher than that in control. Our results show that there is a significant relationship between MTHFD1 G1958A, eNOS G894T and ACE A2350G polymorphisms with CHD. Therefore, The AA and GA genotypes of MTHFD1 G1958A, TT and GT genotypes of eNOS G894T and the AA and GA genotypes of ACE A2350G are susceptible factors for CHD and may increase the risk of CHD.

  4. Relationship of the MTHFD1 (rs2236225), eNOS (rs1799983), CBS (rs2850144) and ACE (rs4343) gene polymorphisms in a population of Iranian pediatric patients with congenital heart defects.

    Science.gov (United States)

    Khatami, Mehri; Ratki, Farzaneh Morteza; Tajfar, Saba; Akrami, Fatemeh

    2017-09-01

    Congenital heart defects are structural cardiovascular malformations that arise from abnormal formation of the heart or major blood vessels during the fetal period. To investigate the association of 4 single nucleotide polymorphisms (SNPs) in the MTHFD1, eNOS, CBS and ACE genes, we evaluated their relationship with CHD in Iranian patients. In this case-control study, a total of 102 children with CHD and 98 control children were enrolled. Four SNPs including MTHFD1 G1958A, eNOS G894T, CBS C-4673G and ACE A2350G were genotyped by PCR-SSCP, Multiplex ARMS PCR and PCR-RFLP methods and confirmed by direct sequencing. We genotyped 102 patients and 98 controls for four polymorphisms by statistically analysis. There were three SNPs including MTHFD1 G1958A, eNOS G894T and ACE A2350G which might increase the risk of CHD, but CBS C-4673G was not significantly different between patients and controls. (P = 0.017, P = 0.048, P = 0.025 and P = 0.081 respectively). The allele frequencies of three SNPs for MTHFD1 G1958A, eNOS G894T and ACE A2350G in CHD are higher than that in control. Our results show that there is a significant relationship between MTHFD1 G1958A, eNOS G894T and ACE A2350G polymorphisms with CHD. Therefore, The AA and GA genotypes of MTHFD1 G1958A, TT and GT genotypes of eNOS G894T and the AA and GA genotypes of ACE A2350G are susceptible factors for CHD and may increase the risk of CHD. Copyright © 2017. Published by Elsevier Taiwan.

  5. Redox-sensitive up-regulation of eNOS by purple grape juice in endothelial cells: role of PI3-kinase/Akt, p38 MAPK, JNK, FoxO1 and FoxO3a.

    Directory of Open Access Journals (Sweden)

    Mahmoud Alhosin

    Full Text Available The vascular protective effect of grape-derived polyphenols has been attributable, in part, to their direct action on blood vessels by stimulating the endothelial formation of nitric oxide (NO. The aim of the present study was to determine whether Concord grape juice (CGJ, which contains high levels of polyphenols, stimulates the expression of endothelial NO synthase (eNOS in porcine coronary artery endothelial cells and, if so, to determine the signaling pathway involved. CGJ dose- and time-dependently increased eNOS mRNA and protein levels and this effect is associated with an increased formation of NO in endothelial cells. The stimulatory effect of CGJ on eNOS mRNA is not associated with an increased eNOS mRNA stability and inhibited by antioxidants such as MnTMPyP, PEG-catalase, and catalase, and by wortmannin (an inhibitor of PI3-kinase, SB 203580 (an inhibitor of p38 MAPK, and SP 600125 (an inhibitor of JNK. Moreover, CGJ induced the formation of reactive oxygen species (ROS in endothelial cells and this effect is inhibited by MnTMPyP, PEG-catalase, and catalase. The CGJ-induced the phosphorylation of p38 MAPK and JNK kinases is abolished by MnTMPyP. CGJ induced phosphorylation of transcription factors FoxO1 and FoxO3a, which regulate negatively eNOS expression, and this effect is prevented by MnTMPyP, PEG-catalase, wortmannin, SB203580 and SP600125. Moreover, chromatin immunoprecipitation assay indicated that the FoxO3a protein is associated with the eNOS promoter in control cells and that CGJ induced its dissociation. Thus, the present study indicates that CGJ up-regulates the expression of eNOS mRNA and protein leading to an increased formation of NO in endothelial cells. The stimulatory effect of CGJ is a redox-sensitive event involving PI3-kinase/Akt, p38 MAPK and JNK pathways, and the inactivation of the FoxO transcription factors, FoxO1 and FoxO3a, thereby preventing their repression of the eNOS gene.

  6. eNOS Glu298Asp polymorphism is associated with development of complicated plaques in patients from Serbia with advanced carotid atherosclerosis

    Directory of Open Access Journals (Sweden)

    Đurić Tamara

    2013-01-01

    Full Text Available Nitric oxide inhibits adhesion of thrombocytes, proliferation and migration of smooth muscle cells and restricts oxidation of atherogenic low-density lipoproteins. Therefore, decreased production or activity of NO may play a role in the initiation, progression or complications of atherosclerosis. The aim of this study was to estimate the effect of Glu298Asp eNOS gene polymorphism on the individual risk for development of complicated carotid atherosclerotic plaque in patients from Serbia with advanced carotid atherosclerosis (CA who had undergone endarterectomy. The study population included 233 patients. eNOS G894T gene polymorphism was identified by PCR and RFLP methods. Multivariate logistic regression analysis showed that Asp298Asp is an independent risk factor for the presence of complicated plaques in CA patients. Patients who were homozygous for the Asp298 allele had an adjusted OR of 4.36 for the development of complicated plaques compared to those that carry the Glu298 allele. Further validation and replication studies are needed. [Projekat Ministarstva nauke Republike Srbije, br. OI175085

  7. Vascular endothelial dysfunction in β-thalassemia occurs despite increased eNOS expression and preserved vascular smooth muscle cell reactivity to NO.

    Directory of Open Access Journals (Sweden)

    Ekatherina Stoyanova

    Full Text Available The hereditary β-thalassemia major condition requires regular lifelong blood transfusions. Transfusion-related iron overloading has been associated with the onset of cardiovascular complications, including cardiac dysfunction and vascular anomalies. By using an untransfused murine model of β-thalassemia major, we tested the hypothesis that vascular endothelial dysfunction, alterations of arterial structure and of its mechanical properties would occur despite the absence of treatments.Vascular function and structure were evaluated ex vivo. Compared to the controls, endothelium-dependent vasodilation with acetylcholine was blunted in mesenteric resistance arteries of β-thalassemic mice while the endothelium-independent vasodilator (sodium nitroprusside produced comparable vessel dilation, indicating endothelial cell impairment with preserved smooth muscle cell reactivity to nitric oxide (NO. While these findings suggest a decrease in NO bioavailability, Western blotting showed heightened expression of aortic endothelial NO synthase (eNOS in β-thalassemia. Vascular remodeling of the common carotid arteries revealed increased medial elastin content. Under isobaric conditions, the carotid arteries of β-thalassemic mice exhibited decreased wall stress and softening due to structural changes of the vessel wall.A complex vasculopathy was identified in untransfused β-thalassemic mice characterized by altered carotid artery structure and endothelial dysfunction of resistance arterioles, likely attributable to reduced NO bioavailability despite enhanced vascular eNOS expression.

  8. Differential effect of beetroot bread on postprandial DBP according to Glu298Asp polymorphism in the eNOS gene: a pilot study.

    Science.gov (United States)

    Hobbs, D A; George, T W; Lovegrove, J A

    2014-12-01

    Our objective was to investigate whether the presence of Glu298Asp polymorphism in the endothelial NO synthase (eNOS) gene differentially affects the postprandial blood pressure response to dietary nitrate-rich beetroot bread. A randomised, single-blind, controlled, crossover acute pilot study was performed in 14 healthy men (mean age: 34±9 years) who were retrospectively genotyped for Glu298Asp polymorphism (7GG; T carriers 7). Volunteers were randomised to receive 200 g beetroot-enriched bread (1.1 mmol nitrate) or control bread (no beetroot; 0.01 mmol nitrate) on two separate occasions 10 days apart. Baseline and incremental area under the curve of blood pressure and NOx (nitrate/nitrite) were measured for a 6-h postprandial period. A treatment × genotype interaction was observed for diastolic blood pressure (Pconsumption of beetroot bread compared with control bread. No significant differences were observed in the GG group. The beneficial diastolic blood pressure reduction was observed only in the T carriers of the Glu298Asp polymorphism in the eNOS gene after consumption of nitrate-rich beetroot bread. These data require confirmation in a larger population group.

  9. Hepatopulmonary syndrome induced by common bile duct ligation in a rabbit model: correlation between pulmonary vascular dilatation on thin-section CT and angiography and serum nitrite concentration or endothelial nitric oxide synthase (eNOS)1 expression

    International Nuclear Information System (INIS)

    Lee, Ki Nam; Yoon, Seong Kuk; Lee, Jin Wha; Kim, Ki Nam; Park, Byung Ho; Kwak, Jong Young; Jeong, Jin Sook; Kim, Young Hoon

    2004-01-01

    To investigate the correlation between radiologic vascular dilatation and serum nitrite concentration and eNOS expression in the endothelial cell and pneumocyte in a rabbit model of hepatopulmonary syndrome induced by common bile duct ligation (CBDL). Thin-section CT scans of the lung and pulmonary angiography were obtained 3 weeks after CBDL (n=6), or a sham operation (n=4), and intrapulmonary vasodilatation was assessed. The diameter and tortuosity of peripheral vessels in the right lower lobe by thin-section CT and angiography at the same level of the right lower lobe in all subjects were correlated to serum nitrite concentration and eNOS (endothelial nitric oxide synthase) expression as determined by immunostaining. The diameters of pulmonary vessels on thin-section CT were well correlated with nitrite concentrations in serum (r=0.92, ρ < 0.001). Dilated pulmonary vessels were significantly correlated with an increased eNOS expression (r=0.94, ρ < 0.0001), and the severity of pulmonary vessel tortuosity was found to be well correlated with serum nitrite concentration (r=0.90, ρ < 0.001). The peripheral pulmonary vasculature in hepatopulmonary syndrome induced by CBLD was dilated on thin-section CT and on angiographs. Our findings suggest that peripheral pulmonary vascular dilatations are correlated with serum nitrite concentrations and pulmonary eNOS expression

  10. L-Arginine ameliorates cardiac left ventricular oxidative stress by upregulating eNOS and Nrf2 target genes in alloxan-induced hyperglycemic rats

    International Nuclear Information System (INIS)

    Ramprasath, Tharmarajan; Hamenth Kumar, Palani; Syed Mohamed Puhari, Shanavas; Senthil Murugan, Ponniah; Vasudevan, Varadaraj; Selvam, Govindan Sadasivam

    2012-01-01

    Highlights: ► L-Arginine treatment reduced the metabolic disturbances in diabetic animals. ► Antioxidant marker proteins were found high in myocardium by L-arginine treatment. ► Elevated antioxidant status, mediates the reduced TBA-reactivity in left ventricle. ► L-Arginine treatment enhanced the Nrf2 and eNOS signaling in left ventricle. ► Improved cell survival signaling by arginine, offers a novel tactic for targeting. -- Abstract: Hyperglycemia is independently related with excessive morbidity and mortality in cardiovascular disorders. L-Arginine-nitric oxide (NO) pathway and the involvement of NO in modulating nuclear factor-E2-related factor-2 (Nrf2) signaling were well established. In the present study we investigated, whether L-arginine supplementation would improve the myocardial antioxidant defense under hyperglycemia through activation of Nrf2 signaling. Diabetes was induced by alloxan monohydrate (90 mg kg −1 body weight) in rats. Both non-diabetic and diabetic group of rats were divided into three subgroups and they were administered either with L-arginine (2.25%) or L-NAME (0.01%) in drinking water for 12 days. Results showed that L-arginine treatment reduced the metabolic disturbances in diabetic rats. Antioxidant enzymes and glutathione levels were found to be increased in heart left ventricles, thereby reduction of lipid peroxidation by L-arginine treatment. Heart histopathological analysis further validates the reversal of typical diabetic characteristics consisting of alterations in myofibers and myofibrillary degeneration. qRT-PCR studies revealed that L-arginine treatment upregulated the transcription of Akt and downregulated NF-κB. Notably, transcription of eNOS and Nrf2 target genes was also upregulated, which were accompanied by enhanced expression of Nrf2 in left ventricular tissue from diabetic and control rats. Under these findings, we suggest that targeting of eNOS and Nrf2 signaling by L-arginine supplementation could be

  11. L-Arginine ameliorates cardiac left ventricular oxidative stress by upregulating eNOS and Nrf2 target genes in alloxan-induced hyperglycemic rats

    Energy Technology Data Exchange (ETDEWEB)

    Ramprasath, Tharmarajan; Hamenth Kumar, Palani; Syed Mohamed Puhari, Shanavas; Senthil Murugan, Ponniah; Vasudevan, Varadaraj [Molecular Cardiology Unit, Department of Biochemistry, Center for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai 625 021, Tamilnadu (India); Selvam, Govindan Sadasivam, E-mail: drselvamgsbiochem@rediffmail.com [Molecular Cardiology Unit, Department of Biochemistry, Center for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai 625 021, Tamilnadu (India)

    2012-11-23

    Highlights: Black-Right-Pointing-Pointer L-Arginine treatment reduced the metabolic disturbances in diabetic animals. Black-Right-Pointing-Pointer Antioxidant marker proteins were found high in myocardium by L-arginine treatment. Black-Right-Pointing-Pointer Elevated antioxidant status, mediates the reduced TBA-reactivity in left ventricle. Black-Right-Pointing-Pointer L-Arginine treatment enhanced the Nrf2 and eNOS signaling in left ventricle. Black-Right-Pointing-Pointer Improved cell survival signaling by arginine, offers a novel tactic for targeting. -- Abstract: Hyperglycemia is independently related with excessive morbidity and mortality in cardiovascular disorders. L-Arginine-nitric oxide (NO) pathway and the involvement of NO in modulating nuclear factor-E2-related factor-2 (Nrf2) signaling were well established. In the present study we investigated, whether L-arginine supplementation would improve the myocardial antioxidant defense under hyperglycemia through activation of Nrf2 signaling. Diabetes was induced by alloxan monohydrate (90 mg kg{sup -1} body weight) in rats. Both non-diabetic and diabetic group of rats were divided into three subgroups and they were administered either with L-arginine (2.25%) or L-NAME (0.01%) in drinking water for 12 days. Results showed that L-arginine treatment reduced the metabolic disturbances in diabetic rats. Antioxidant enzymes and glutathione levels were found to be increased in heart left ventricles, thereby reduction of lipid peroxidation by L-arginine treatment. Heart histopathological analysis further validates the reversal of typical diabetic characteristics consisting of alterations in myofibers and myofibrillary degeneration. qRT-PCR studies revealed that L-arginine treatment upregulated the transcription of Akt and downregulated NF-{kappa}B. Notably, transcription of eNOS and Nrf2 target genes was also upregulated, which were accompanied by enhanced expression of Nrf2 in left ventricular tissue from diabetic

  12. eNOS se correlaciona com a biogênese mitocondrial em corações com cardiopatia congênita e cianose

    Directory of Open Access Journals (Sweden)

    Juan Xiao

    2012-09-01

    Full Text Available FUNDAMENTO: O programa de biogênese mitocondrial no coração parece apresentar remodelação adaptativa após estresse biomecânico e oxidativo. Os mecanismos adaptativos que protegem o metabolismo do miocárdio durante a hipóxia são coordenados, em parte, pelo óxido nítrico (NO. OBJETIVO: Observar a biogênese mitocondrial e expressão do óxido nítrico sintase (NOS em corações de cardiopatia congênita com cianose; discutir a resposta mitocondrial à hipóxia crônica do miocárdio. MÉTODOS: Foram investigados 20 pacientes com defeitos cardíacos cianóticos (n = 10 ou acianóticos (n = 10. Foram estudadas amostras do miocárdio na via de saída ventricular direita, tomadas durante a operação. A análise morfométrica de mitocôndrias foi realizada por microscopia eletrônica de transmissão. A relação mtDNA/nDNA foi determinada com PCR em tempo real. Os níveis de transcrição da subunidade I da citocromo c oxidase (COXI, coativador-1α do receptor γ ativado por proliferador de peroxissoma (PGC-1α, o fator respiratório nuclear 1 (NRF1, e fator de transcrição mitocondrial A (Tfam foram detectados por reação em cadeia da polimerase via transcriptase reversa (RT-PCR ativado por fluorescência em tempo real. Os níveis proteicos de COXI e nNOS, iNOS e eNOS foram medidos por técnica de Western Blot. RESULTADOS: A densidade volumétrica mitocondrial (Vv e a densidade numérica (Nv foram significativamente elevadas em pacientes com cianose, em comparação com a cardiopatia congênita acianótica. MtDNA elevada e suprarregulação dos níveis de COXI, PGC-1 α, NRF1 e Tfam mRNA foram observadas em pacientes cianóticos. Os níveis de proteína de COXI e eNOS foram significativamente maiores no miocárdio de pacientes cianóticos que nos de acianóticos. Os níveis de transcrição do PGC-1α se correlacionam com os níveis de eNOS. CONCLUSÃO: A biogênese mitocondrial é ativada no miocárdio da via de saída ventricular na

  13. Age and gender differences in the influences of eNOS T-786C polymorphism on arteriosclerotic parameters in general population in Japan.

    Science.gov (United States)

    Hashimoto, Marowa; Miyai, Nobuyuki; Hattori, Sonomi; Iwahara, Akihiko; Utsumi, Miyoko; Arita, Mikio; Takeshita, Tatsuya

    2016-07-01

    The influence of T-786C polymorphism in the promoter region of endothelial nitric oxide synthase (eNOS) on arteriosclerotic parameters by age and gender were examined. Brachial-ankle pulse wave velocity (baPWV), heart-rate adjusted augmentation index (AIx@75), pulse pressure (PP) and albumin-creatinine ratio (ACR) were assessed as arteriosclerotic parameters in addition to non-high-density lipoprotein cholesterol (non-HDL-C) to HDL-C (non-HDL-C/HDL-C) ratio in 1499 participants. T-786C polymorphism (rs2070744) was screened using a TaqMan allelic discrimination assay. Analyses of covariance were carried. Women with the non-C allele showed significantly lower AIx@75 in participants aged gender differences, possibly involving antioxidative and/or endothelial signaling other than inflammatory signaling.

  14. H2O2 Treatment of HUVECs Facilitates PKC Mediated Thr495 Phosphorylation on eNOS when Pre-treated with High Glucose Levels

    DEFF Research Database (Denmark)

    Guterbaum, Thomas J; Braunstein, Thomas H; Fossum, Anna

    2015-01-01

    Objective: Metabolic syndrome entails hypertension, hyperglycemia, obesity and hypercholesterolemia. This syndrome increases the risk of cardiovascular disease and diabetes. Hyperglycemia during coronary reperfusion is associated with a poor prognosis. Contrastingly, targeting correction of hyper......Objective: Metabolic syndrome entails hypertension, hyperglycemia, obesity and hypercholesterolemia. This syndrome increases the risk of cardiovascular disease and diabetes. Hyperglycemia during coronary reperfusion is associated with a poor prognosis. Contrastingly, targeting correction....... The presence of reactive oxygen species (ROS) in both mitochondria and cytoplasm was measured by fluorescence activated cell sorting (FACS). Phosphorylation of endothelial nitric oxide synthase (eNOS) on threonine 495 (Thr495) and serine 1177 (Ser1177) was assessed by western blotting. Short-term (20 hours...

  15. 2,4,6-Tri-amino-1,3,5-triazin-1-ium 3-(prop-2-eno-yloxy)propano-ate acrylic acid monosolvate monohydrate.

    Science.gov (United States)

    Sangeetha, V; Kanagathara, N; Chakkaravarthi, G; Marchewka, M K; Anbalagan, G

    2013-05-01

    The asymmetric unit of the title salt, C3H7N6 (+)·C6H7O4 (-)·C3H4O2·H2O, contains a 2,4,6-tri-amino-1,3,5-triazin-1-ium cation, a 3-(prop-2-eno-yloxy)propano-ate anion and acrylic acid and water solvent mol-ecules in a 1:1:1:1 ratio and with each species in a general position. In the crystal, the components are linked into a supra-molecular layer in the bc plane via a combination of O-H⋯O, N-H⋯N and N-H⋯O hydrogen bonding. The crystal studied was a non-merohedral twin, the minor component contribution being approximately 26%.

  16. Treadmill exercise alleviates diabetic cardiomyopathy by suppressing plasminogen activator inhibitor expression and enhancing eNOS in streptozotocin-induced male diabetic rats.

    Science.gov (United States)

    Chengji, Wang; Xianjin, Fan

    2018-04-01

    To investigate the biological mechanism of the effect of different intensity exercises on diabetic cardiomyopathy. 87 raise specific pathogen SPF healthy 6-week-old male Sprague-Dawley rats, fed 6 weeks with high-fat diet for rats were used, and a diabetic model was established by intraperitoneal injection of streptozotocin - randomly selected 43 rats were divided into Diabetic control group (DCG, n  = 10), Diabetic exercise group 1 (DEG1, n  = 11), Diabetic exercise group 2 (DEG2, n  = 11) and Diabetic exercise group 3 (DEG3, n  = 11). The rats in DEG1 were forced to run on a motorized treadmill, the exercise load consisted of running at a speed of 10 m/min, the exercise load of the rats in DEG2 were running at a speed of 15 m/min, the exercise load of the rats in DEG3 were running at a speed of 20 m/min, for one hour once a day for 6 weeks. After 6 weeks of exercise intervention, glucose metabolism-related indexes in rats such as blood glucose (FBG), glycosylated serum protein (GSP) and insulin (FINS); cardiac fibrinolytic system parameters such as PAI-1 (plasminogen activator inhibitor 1), Von Willebrand factor (vWF), protein kinase C (PKC) and diacylglycerol (DAG); and serum level of NO, eNOS and T-NOS were measured. Compared with DCG, fasting blood glucose and GSP were decreased, while insulin sensitivity index and insulin level were increased in all rats of the three exercise groups. FBG decrease was statistically significant ( P  diabetic rats; myocardial PAI-1 in DEG1, DEG2 and DEG3 rats decreased significantly ( P  diabetic cardiomyopathy by affecting the levels of PAI-1 and eNOS, and there is a dependence on intensity. © 2018 The authors.

  17. San-Huang-Xie-Xin-Tang Prevents Rat Hearts from Ischemia/Reperfusion-Induced Apoptosis through eNOS and MAPK Pathways

    Directory of Open Access Journals (Sweden)

    Shu-Fen Liou

    2011-01-01

    Full Text Available San-Huang-Xie-Xin-Tang (SHXT is a traditional Chinese medication consisting of three herbs, namely Coptidis rhizome, Scutellariae radix and Rhei rhizome. This study aimed to examine the cardioprotective effects of SHXT in a rat model of acute myocardial apoptosis induced by ischemia/reperfusion (I/R. Vehicle (intravenous saline or SHXT (intravenous or oral was administered prior to I/R (occlusion of left coronary artery for 45 min followed by reperfusion for 2 h. In the vehicle group, myocardial I/R caused myocardial infarction with increased plasma cardiac enzymes, severe arrhythmia and mortality. Myocardial apoptosis was induced by I/R as evidenced by DNA ladder and Bcl-2/Bax ratio. In the SHXT group, we found that SHXT significantly reduced plasma levels of cardiac enzymes, arrhythmia scores (from 5 ± 1 to 2 ± 1, P<.01 and mortality rate (from 53 to 0%, P<.01. In addition, pretreatment with intravenous SHXT reduced the infarct size dose-dependently when compared with the vehicle group (10 mg kg−1: 14.0 ± 0.2 versus 44.5 ± 5.0%, and 30 mg kg−1: 6.2 ± 1.2% versus 44.5 ± 5.0%, both P<.01. Similarly, oral administration of SHXT reduced the infarct size dose-dependently. Furthermore, SHXT markedly decreased the apoptosis induced by I/R with increased Bcl-2/Bax ratio. Finally, we found that SHXT counteracted the I/R-induced downstream signaling, resulting in increased myocardial eNOS expression and plasma nitrite, and decreased activation of ERK1/2, p38 and JNK. These data suggest that SHXT has cardioprotective effects against I/R-induced apoptosis, and that these effects are mediated, at least in part, by eNOS and MAPK pathways.

  18. Role of C677T and A1298C MTHFR, A2756G MTR and -786 C/T eNOS gene polymorphisms in atrial fibrillation susceptibility.

    Directory of Open Access Journals (Sweden)

    Betti Giusti

    Full Text Available BACKGROUND: Hyperhomocysteinemia has been suggested to play a role in the NonValvular Atrial Fibrillation (NVAF pathogenesis. Polymorphisms in genes coding for homocysteine (Hcy metabolism enzymes may be associated with hyperhomocysteinemia and NVAF. METHODOLOGIES: 456 NVAF patients and 912 matched controls were genotyped by an electronic microchip technology for C677T and A1298C MTHFR, A2756G MTR, and -786C/T eNOS gene polymorphisms. Hcy was determined by an immunoassay method. PRINCIPAL FINDINGS: The genotype distribution of the four polymorphisms as well as genotype combinations did not differ in patients and controls. Hcy was higher in patients than in controls (15.2, 95%CI 14.7-15.7 vs 11.3, 95%CI 11.0-11.6 micromol/L; p<0.0001. In both populations, a genotype-phenotype association (p<0.0001 between Hcy and C677T MTHFR polymorphism was observed; in controls a significant (p = 0.029 association between tHcy and -786C/T eNOS polymorphism was also observed. At the multivariate analysis the NVAF risk significantly increased in the upper quartiles of Hcy compared to the lowest: OR from 2.8 (1.68-4.54 95%CI in Q2 to 12.9 (7.96-21.06 95%CI in Q4. CONCLUSIONS: Our data demonstrated the four polymorphisms, although able, at least in part, to affect Hcy, were not associated with an increased risk of NVAF per se or in combination.

  19. Abeeb olufemi Salaam Community Reintegration Oyo, Oyo State ...

    African Journals Online (AJOL)

    list of illegal drugs (e.g., cannabis, heroin, co- caine, amphetamines): (a) they had ever used in their life; (b) they had used during the past twelve months. Further to the list of illegal drugs, the participants were asked to indicate whether they had used any alcoholic beverag- es (e.g., dry gin, kokino), solvents (e.g., glue, petrol ...

  20. Abeeb olufemi Salaam Community Reintegration Oyo, Oyo State ...

    African Journals Online (AJOL)

    High rates of cannabis, tobacco (nicotine), rophynol, codeine ... their children in Islamic education, called alm- ajiri (Abdulmalik ... cause there are few resources at the teachers' disposal .... graphic profiles, different types of drug and ..... (1996). Drug use among street in southern. Brazil. Drug and Alcohol Dependence, 43.

  1. Dual-Specificity Phosphatase 4 Overexpression in Cells Prevents Hypoxia/Reoxygenation-Induced Apoptosis via the Upregulation of eNOS

    Science.gov (United States)

    Dougherty, Julie A.; Kilbane Myers, Joanna; Khan, Mahmood; Angelos, Mark G.; Chen, Chun-An

    2017-01-01

    Mitogen-activated protein kinases (MAPKs) signaling cascades regulate several cellular functions, including differentiation, proliferation, survival, and apoptosis. The duration and magnitude of phosphorylation of these MAPKs are decisive determinants of their physiological functions. Dual-specificity phosphatases exert kinetic control over these signaling cascades. Previously, we demonstrated that DUSP4−/− hearts sustain a larger infarct and have poor functional recovery, when isolated hearts were subjected to ischemia/reperfusion. Uncontrolled p38 activation and upregulation of Nox4 expression are the main effectors for this functional alteration. Here, dual-specificity phosphatase 4 (DUSP4) overexpression in endothelial cells was used to investigate the role of DUSP4 on the modulation of reactive oxygen species (ROS) generation and vascular function, when cells were subjected to hypoxia/reoxygenation (H/R) insult. Immunostaining with cleaved caspase-3 revealed that DUSP4 overexpression prevents caspase-3 activation and apoptosis after H/R. The beneficial effects occur via modulating p38 activity, increased NO bioavailability, and reduced oxidative stress. More importantly, DUSP4 overexpression upregulates eNOS protein expression (1.62 ± 0.33 versus 0.65 ± 0.16) during H/R-induced stress. NO is a critical small molecule involved in regulating vascular tone, vascular growth, platelet aggregation, and modulation of inflammation. The level of NO generation determined using DAF-2 fluorescence demonstrated that DUSP4 overexpression augments NO production and thus improves vascular function. The level of superoxide generated from cells after being subjected to H/R was determined using dihydroethidium-HPLC method. The results suggested that DUSP4 overexpression in cells decreases H/R-induced superoxide generation (1.56 ± 0.14 versus 1.19 ± 0.05) and thus reduces oxidant stress. This also correlates with the reduction in the total protein S

  2. Obesity, inflammation, and exercise training: relative contribution of iNOS and eNOS in the modulation of vascular function in the mouse aorta

    Directory of Open Access Journals (Sweden)

    Josiane Fernandes da Silva

    2016-09-01

    Full Text Available Background - The understanding of obsesity-related vascular dysfunction remains controversial mainly because of the diseases associated with vascular injury. Exercise training is known to prevent vascular dysfunction. Using an obesity model without comorbidities, we aimed at investigating the underlying mechanism of vascular dysfunction and how exercise interferes with this process.Methods - High-sugar diet was used to induce obesity in mice. Exercise training was performed 5 days/week. Body weight, energy intake, and adipose tissues were assessed; blood metabolic and hormonal parameters were determined; and serum TNFα was measured. Blood pressure and heart rate were assessed by plethysmography. Changes in aortic isometric tension were recorded on myograph. Western blot was used to analyze protein expression. Nitric oxide (NO was evaluated using fluorescence microscopy. Antisense oligodeoxynucleotides were used for inducible nitric oxide synthase isoform (iNOS knockdown.Results - Body weight, fat mass, total cholesterol, low-density lipoprotein cholesterol fraction, insulin, and leptin were higher in the sedentary obese group (SD than in the sedentary control animals (SS. Exercise training prevented these changes. No difference in glucose tolerance, insulin sensitivity, blood pressure, and heart rate was found. Decreased vascular relaxation and reduced endothelial nitric oxide synthase (eNOS functioning in the SD group were prevented by exercise. Contractile response to phenylephrine was decreased in the aortas of the wild SD mice, compared with that of the SS group; however, no alteration was noted in the SD iNOS-/- animals. The decreased contractility was endothelium-dependent, and was reverted by iNOS inhibition or iNOS silencing. The aortas from the SD group showed increased basal NO production, serum TNFα, TNF receptor-1, and phospho-IκB. Exercise training attenuated iNOS-dependent reduction in contractile response in high-sugar diet

  3. Effects of stimulation of soluble guanylate cyclase on diabetic nephropathy in diabetic eNOS knockout mice on top of angiotensin II receptor blockade.

    Directory of Open Access Journals (Sweden)

    Ina M Ott

    Full Text Available The prevalence of diabetes mellitus and its complications, such as diabetic nephropathy (DN, is rising worldwide and prevention and treatment are therefore becoming increasingly important. Therapy of DN is particularly important for patients who do not adequately respond to angiotensin receptor blocker (ARB treatment. Novel approaches include the stimulation of soluble guanylate cyclase (sGC as it is reported to have beneficial effects on cardiac and renal damage. We aimed to investigate the effects of the sGC stimulator riociguat and ARB telmisartan on kidney function and structure in a hypertensive model of diabetic nephropathy. Seventy-six diabetic male eNOS knockout C57BL/6J mice were randomly divided after having received streptozotocin: telmisartan (1 mg/kg/d, riociguat (3 mg/kg/d, riociguat+telmisartan (3+1 mg/kg/d, and vehicle. Fourteen mice were used as non-diabetic controls. Treatment duration was 11 weeks. Glucose concentrations were increased and similar in all diabetic groups. Telmisartan insignificantly reduced blood pressure by 5.9 mmHg compared with diabetic controls (111.2±2.3 mmHg vs. 117.1±2.2 mmHg; p = 0.071. Treatment with riociguat both alone and in combination with telmisartan led to a significant reduction of blood pressure towards diabetic vehicle (105.2±2.5 mmHg and 105.0±3.2 mmHg, respectively, vs. 117.1±2.2 mmHg. Combined treatment also significantly decreased albuminuria compared with diabetic controls (47.3±9.6 µg/24 h vs. 170.8±34.2 µg/24 h; p = 0.002 reaching levels similar to those of non-diabetic controls (34.4±10.6 µg/24 h, whereas the reduction by single treatment with either telmisartan (97.8±26.4 µg/24 h or riociguat (97.1±15.7 µg/24 h was not statistically significant. The combination treatment led to a significant (p<0.01 decrease of tissue immunoreactivity of malondialdehyde, as consequence of reduced oxidative stress. In conclusion, stimulation of sGC significantly reduced urinary

  4. Ellagic Acid Prevents L-NAME-Induced Hypertension via Restoration of eNOS and p47phox Expression in Rats

    Directory of Open Access Journals (Sweden)

    Thewarid Berkban

    2015-06-01

    Full Text Available The effect of ellagic acid on oxidative stress and hypertension induced by Nω-Nitro-l-arginine methyl ester hydrochloride (L-NAME was investigated. Male Sprague-Dawley rats were administrated with L-NAME (40 mg/kg/day for five weeks. L-NAME induced high systolic blood pressure (SBP and increased heart rate (HR, hindlimb vascular resistance (HVR and oxidative stress. Concurrent treatment with ellagic acid (7.5 or 15 mg/kg prevented these alterations. Co-treatment with ellagic acid was associated with up-regulation of endothelial nitric oxide synthase (eNOS protein production and alleviation of oxidative stress as indicated by decreased superoxide production in the vascular tissue, reduced plasma malondialdehyde levels, reduced NADPH oxidase subunit p47phox expression and increased plasma nitrate/nitrite levels. Our results indicate that ellagic acid attenuates hypertension by reducing NADPH oxidase subunit p47phox expression, which prevents oxidative stress and restores NO bioavailability.

  5. Synergistic Antihypertensive Effect of Carthamus tinctorius L. Extract and Captopril in l-NAME-Induced Hypertensive Rats via Restoration of eNOS and AT1R Expression

    Directory of Open Access Journals (Sweden)

    Putcharawipa Maneesai

    2016-02-01

    Full Text Available This study examined the effect of Carthamus tinctorius (CT extract plus captopril treatment on blood pressure, vascular function, nitric oxide (NO bioavailability, oxidative stress and renin-angiotensin system (RAS in Nω-Nitro-l-arginine methyl ester (l-NAME-induced hypertension. Rats were treated with l-NAME (40 mg/kg/day for five weeks and given CT extract (75 or 150 or 300 or 500 mg/kg/day: captopril (5 mg/kg/day or CT extract (300 mg/kg/day plus captopril (5 mg/kg/day for two consecutive weeks. CT extract reduced blood pressure dose-dependently, and the most effective dose was 300 mg/kg/day. l-NAME-induced hypertensive rats showed abnormalities including high blood pressure, high vascular resistance, impairment of acetylcholine-induced vasorelaxation in isolated aortic rings and mesenteric vascular beds, increased vascular superoxide production and plasma malondialdehyde levels, downregulation of eNOS, low level of plasma nitric oxide metabolites, upregulation of angiotensin II type 1 receptor and increased plasma angiotensin II. These abnormalities were alleviated by treatment with either CT extract or captopril. Combination treatment of CT extract and captopril normalized all the abnormalities found in hypertensive rats except endothelial dysfunction. These data indicate that there are synergistic antihypertensive effects of CT extract and captopril. These effects are likely mediated by their anti-oxidative properties and their inhibition of RAS.

  6. Report of the results of the fiscal 1997 regional consortium R and D project. Regional consortium energy field / Study on a new production process of functional thin films suitable for recycling and its application to colored glasses (first fiscal year); 1997 nendo chiiki consortium kenkyu kaihatsu jigyo. Chiiki consortium energy bun`ya / recycle ni tekishita kinosei usumaku no shinki seizoho to chakushoku glass eno oyo ni kansuru kenkyu kaihatsu (daiichi nendo) seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The paper described the fiscal 1997 result. Using organic pigment and dye, the basic composition of sol-gel colored coating liquid for glass bottles and sheets was selected to clarify characteristics of gel films. Moreover, chemical modification and optical sensitivity of metallic alkoxide were studied to obtain a trially produced colored glass bottle use coating liquid. As to sheet glass, strength of the gel film is low, which requires further improvement. In relation to optical sensitive gel films, the reaction of various metallic alkoxides and {beta}-diketones was discussed to clarify chemical reactivity with utltaviolet rays. Trial design was also conducted of the coating equipment. The paper examined by literature the present status of recycling systems of colored glass bottles and the technical development in European countries. The problem is a method to wash colored bottles for sterilization. To make colored films durable, it is necessary to form films by organic-inorganic hybrid thin films. Also discussed was a possibility of changing the washing method by administrative guidance. 27 refs., 62 figs., 42 tabs.

  7. Report on survey for possibility of applying bio-technologies to biomass in fiscal 1999. Aiming at developing a kitchen refuse and waste water treatment and energy production system that can be installed as an ancillary facility of buildings; 1999 nendo biomass eno bio technology oyo kanosei chosa hokokusho. Biru nado no futai setsubi to shite secchi kanona, chukai, haisui nado no shori narabi ni energy seisan system no kaihatsu wo mezashite

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This paper describes the survey and discussion on a system to treat microorganisms generated from organic wastes and recover bio-gas energy as an ancillary facility of buildings. The roof of a building is the most suitable location in terms of open space and odor problem, and because the waste liquid after energy recovery can be flown into the city sewage system. Suitable processes for energy recovery are the primary fermentation, followed further by second stage fermentation purposed of reducing BOD. Since rapid enhancement of the efficiency cannot be expected from the present methane fermentation technologies, it is worth discussing to convert the first step from methane fermentation to hydrogen fermentation, for which technological development is indispensable. Permission by the national or local government would be an important condition. Organic wastes treatment systems with different scales may be considered from wastes treatment in each house to treatment of wastes after collection on the whole city basis. Treating wastes with high water content, such as kitchen refuses and human waste is beneficial among organic wastes being collected and treated by local governments. It is beneficial because sorted collection for that purpose can be carried out, and existing incineration systems can be operated more efficiently. (NEDO)

  8. Influence of training status and eNOS haplotypes on plasma nitrite concentrations in normotensive older adults: a hypothesis-generating study.

    Science.gov (United States)

    da Silva, Roberta Fernanda; Sertório, Jonas Tadeu Cau; Lacchini, Riccardo; Trapé, Atila Alexandre; Tanus-Santos, José Eduardo; Rush, James W E; Amaral, Sandra Lia; Zago, Anderson Saranz

    2014-12-01

    The purpose of this study was to evaluate the relationship between 3 eNOS gene polymorphisms and training status (TS) in affecting plasma nitrite concentration (NO2) in normotensive adults over 50 years old. Resting blood pressure (BP) was measured in all participants (n = 101). Plasma was taken to analyze: lipid profile, nitrite concentration (NO2) and lipid peroxide levels (T-BARS). Also, genomic DNA was extracted from plasma for genotyping NOS3 polymorphisms (-786T>C; 894G>T; and VNTR in intron 4). TS was determined by one-mile walk test and Functional Fitness Test Battery from AAHPERD (TS1-regular TS; TS2-good TS; and TS3-very good TS). BP was not influenced by TS, but NO2 was 15% higher in TS3 (123 ± 27 nM) compared to TS-2 (106 ± 22 nM). No differences were found in plasma NO2 in the haplotype analyses. However, the presence of the C allele (T-786C) and ASP allele (Glu298Asp) was found to enhance the correlation between TS and NO2 levels (r = 0.492 in C/4b/ASP haplotype and r = 0.855 in C/4a/ASP haplotype). This study thus identifies NOS3 polymorphism-dependent sensitivity to the effects of physical training on plasma NO2. Maintenance of good levels of training status, in carriers of C allele for T-786C polymorphism, combined with ASP allele for Glu298Asp polymorphism, may result in an increase in the NO2 plasma concentrations, which may reflect improved NO bioavailability in older adult normotensive individuals.

  9. A combination of genistein and magnesium enhances the vasodilatory effect via an eNOS pathway and BK(Ca) current amplification.

    Science.gov (United States)

    Sun, Lina; Hou, Yunlong; Zhao, Tingting; Zhou, Shanshan; Wang, Xiaoran; Zhang, Liming; Yu, Guichun

    2015-04-01

    The phytoestrogen genistein (GST) and magnesium have been independently shown to regulate vascular tone; however, their individual vasodilatory effects are limited. The aim of this study was to examine the combined effects of GST plus magnesium on vascular tone in mesenteric arteries. The effects of pretreatment with GST (0-200 μmol/L), MgCl2 (0-4.8 mmol/L) and GST plus MgCl2 on 10 μmol/L phenylephrine (PE) precontracted mesenteric arteries in rats were assessed by measuring isometric force. BK(Ca) currents were detected by the patch clamp method. GST caused concentration- and partial endothelium-dependent relaxation. Magnesium resulted in dual adjustment of vascular tone. Magnesium-free solution eliminated the vasodilatation of GST in both endothelium-intact and denuded rings. GST (50 μmol/L) plus magnesium (4.8 mmol/L) caused stronger relaxation in both endothelium-intact and denuded rings. Pretreatment with the nitric oxide synthase (NOS) inhibitor L-N-nitroarginine methyl ester (L-NAME, 100 μmol/L) significantly inhibited the effects of GST, high magnesium, and the combination of GST and magnesium. BK(Ca) currents were amplified to a greater extent when GST (50 μmol/L) was combined with 4.8 versus 1.2 mmol/L Mg(2+). Our data suggest that GST plus magnesium provides enhanced vasodilatory effects in rat mesenteric arteries compared with that observed when either is used separately, which was related to an eNOS pathway and BK(Ca) current amplification.

  10. MicroRNA-27b plays a role in pulmonary arterial hypertension by modulating peroxisome proliferator-activated receptor γ dependent Hsp90-eNOS signaling and nitric oxide production

    Energy Technology Data Exchange (ETDEWEB)

    Bi, Rui; Bao, Chunrong; Jiang, Lianyong; Liu, Hao; Yang, Yang; Mei, Ju; Ding, Fangbao, E-mail: dbcar126@126.com

    2015-05-01

    Pulmonary artery endothelial dysfunction is associated with pulmonary arterial hypertension (PAH). Based on recent studies showing that microRNA (miR)-27b is aberrantly expressed in PAH, we hypothesized that miR-27b may contribute to pulmonary endothelial dysfunction and vascular remodeling in PAH. The effect of miR-27b on pulmonary endothelial dysfunction and the underlying mechanism were investigated in human pulmonary artery endothelial cells (HPAECs) in vitro and in a monocrotaline (MCT)-induced model of PAH in vivo. miR-27b expression was upregulated in MCT-induced PAH and inversely correlated with the levels of peroxisome proliferator-activated receptor (PPAR)-γ, and miR-27b inhibition attenuated MCT-induced endothelial dysfunction and remodeling and prevented PAH associated right ventricular hypertrophy and systolic pressure in rats. PPARγ was confirmed as a direct target of miR-27b in HPAECs and shown to mediate the effect of miR-27b on the disruption of endothelial nitric oxide synthase (eNOS) coupling to Hsp90 and the suppression of NO production associated with the PAH phenotype. We showed that miR-27b plays a role endothelial function and NO release and elucidated a potential mechanism by which miR-27b regulates Hsp90-eNOS and NO signaling by modulating PPARγ expression, providing potential therapeutic targets for the treatment of PAH. - Highlights: • miR-27b plays a role in endothelial function and NO release. • miR-27b inhibition ameliorates MCT-induced endothelial dysfunction and PAH. • miR-27b targets PPARγ in HPAECs. • miR-27b regulates PPARγ dependent Hsp90-eNOS and NO signaling.

  11. Impacto del ENOS sobre los rendimientos de maíz en la región pampeana argentina Impact of the ENSO on corn yields in the Argentinean pampas region

    Directory of Open Access Journals (Sweden)

    M. E. Fernández Long

    2011-06-01

    Full Text Available El fenómeno de “El Niño - Oscilación del Sur” (ENOS es uno de los principales responsables de la variabilidad climática interanual, con influencia sobre la región pampeana argentina. El objetivo de este trabajo fue analizar el impacto del ENOS sobre las variaciones anuales de la producción de maíz. La región fue dividida en 10 zonas en las cuales los rendimientos tienen una variabilidad interanual homogénea. Se utilizaron diferentes índices del ENOS. Los resultados indicaron que, en la mayor parte de la región, los desvíos de los rendimientos son, en general, positivos durante eventos “El Niño” y negativos durante “La Niña”. Sin embargo, el impacto es muy fuerte al norte y centro de la región analizada, y se debilita hacia el sur. En el sudeste de la provincia de Buenos Aires el comportamiento es diferente que en el resto. Los índices promediados de mayo a julio son, en general, un buen indicador de la influencia del ENOS sobre la productividad de los cultivos, y brindan una adecuada información para la toma de decisiones de la empresa agropecuaria, con suficiente anticipación respecto del comienzo de la campaña.The “El Niño Southern Oscillation” (ENSO phenomenon is one of the main responsible factor for interannual climate variability in the “pampas” region. This work aims to analyze the impact of ENSO on the annual variations of corn production. The region was divided into 10 areas in which yields have a homogeneous interannual variability. Five ENSO indexes were used The results indicated that, in most parts of the region, the deviations of trend line yields are, in general, positive during “El Niño” events and negative during “La Niña”. However, the impact is very strong in the North and Centre of the analyzed region and weakens southward. In the southeast of the province of Buenos Aires, the behavior is different than the rest. Averaging indexes from May to July we obtained a good indicator

  12. Puruvana puruvanavana : [luuletused] / Eno Raud

    Index Scriptorium Estoniae

    Raud, Eno, 1928-1996

    2000-01-01

    Sisu: Puruvana puruvanavana ; Vetesell ; Pada ja katel ; Nääripäkapikk ; Vanapaar ; Mere peremees ; Lepamaim ; Kiilaspää kiilasjääl ; Tõugu unistus ; Naljatilk silk ; Muttide jalutuskäik ; Hiir lumes ; Kalakari salakaril ; Naljalammas ; Mesilastest ; Kure mure ; Voki laul karule ; Põrsalaul ; Kurk ja kõrvits ; Tuhk ja tina ; Õige pea ja vale pea ; Suu pea, puupea! ; Siga õuel

  13. Efeitos da atorvastatina e do polimorfismo T-786C do gene eNOS sobre parâmetros do metabolismo lipídico plasmático

    Directory of Open Access Journals (Sweden)

    Vanessa Helena de Souza Zago

    2013-01-01

    Full Text Available FUNDAMENTO: A atividade do óxido nítrico sintase endotelial (eNOS pode ser modulada pelo colesterol da lipoproteína de alta densidade (HDL-C, estatinas ou polimorfismos, como o T-786C de eNOS. OBJETIVO: Este estudo teve como objetivo avaliar se o polimorfismo T-786C está associado a alterações nos efeitos da atorvastatina no perfil lipídico, nas concentrações de metabólitos de óxido nítrico (NO e da proteína C reativa de alta sensibilidade (PCR-as. MÉTODOS: Trinta voluntários do sexo masculino, assintomáticos, com idade entre 18-56 anos foram genotipados e classificados de acordo com a ausência (TT, n = 15 ou presença (CC, n = 15 do polimorfismo. Eles foram selecionados aleatoriamente para a utilização de placebo e atorvastatina (10 mg/dia por 14 dias. Após cada tratamento foram medidos lípides, lipoproteínas, frações HDL2 e HDL3, atividade da proteína de transferência de colesteril éster (CETP, metabólitos de NO e PCR-as. RESULTADOS: As comparações entre genótipos após a administração de placebo mostraram aumento da atividade da CETP polimorfismo-dependente (TT, 12 ± 7; CC, 22 ± 12, p < 0,05. As análises da interação entre os tratamentos indicaram que a atorvastatina tem efeito sobre colesterol, LDL, nitrito e razões lípides/proteínas (HDL2 e HDL3 (p < 0,001 em ambos os genótipos. É interessante notar as interações genótipo/droga sobre a CETP (p < 0,07 e a lipoproteína (a [Lp(a] (p < 0,056, levando a uma diminuição limítrofe da CETP, embora sem afetar a Lp(a. A PRC-as não mostrou alterações. CONCLUSÃO: Os resultados sugerem que o tratamento com estatinas pode ser relevante para a prevenção primária da aterosclerose em pacientes com o polimorfismo T-786C do eNOS, considerando os efeitos no metabolismo lipídico.

  14. 2,4,6-Tri­amino-1,3,5-triazin-1-ium 3-(prop-2-eno­yloxy)propano­ate acrylic acid monosolvate monohydrate

    Science.gov (United States)

    Sangeetha, V.; Kanagathara, N.; Chakkaravarthi, G.; Marchewka, M. K.; Anbalagan, G.

    2013-01-01

    The asymmetric unit of the title salt, C3H7N6 +·C6H7O4 −·C3H4O2·H2O, contains a 2,4,6-tri­amino-1,3,5-triazin-1-ium cation, a 3-(prop-2-eno­yloxy)propano­ate anion and acrylic acid and water solvent mol­ecules in a 1:1:1:1 ratio and with each species in a general position. In the crystal, the components are linked into a supra­molecular layer in the bc plane via a combination of O—H⋯O, N—H⋯N and N—H⋯O hydrogen bonding. The crystal studied was a non-merohedral twin, the minor component contribution being approximately 26%. PMID:23723892

  15. The Streptococcus pyogenes Serotype M49 Nra-Ralp3 Transcriptional Regulatory Network and Its Control of Virulence Factor Expression from the Novel eno ralp3 epf sagA Pathogenicity Region▿ †

    Science.gov (United States)

    Kreikemeyer, Bernd; Nakata, Masanobu; Köller, Thomas; Hildisch, Hendrikje; Kourakos, Vassilios; Standar, Kerstin; Kawabata, Shigetada; Glocker, Michael O.; Podbielski, Andreas

    2007-01-01

    Many Streptococcus pyogenes (group A streptococcus [GAS]) virulence factor- and transcriptional regulator-encoding genes cluster together in discrete genomic regions. Nra is a central regulator of the FCT region. Previous studies exclusively described Nra as a transcriptional repressor of adhesin and toxin genes. Here transcriptome and proteome analysis of a serotype M49 GAS strain and an isogenic Nra mutant of this strain revealed the complete Nra regulon profile. Nra is active in all growth phases tested, with the largest regulon in the transition phase. Almost exclusively, virulence factor-encoding genes are repressed by Nra; these genes include the GAS pilus operon, the capsule synthesis operon, the cytolysin-mediated translocation system genes, all Mga region core virulence genes, and genes encoding other regulators, like the Ihk/Irr system, Rgg, and two additional RofA-like protein family regulators. Surprisingly, our experiments revealed that Nra additionally acts as a positive regulator, mostly for genes encoding proteins and enzymes with metabolic functions. Epidemiological investigations revealed strong genetic linkage of one particular Nra-repressed regulator, Ralp3 (SPy0735), with a gene encoding Epf (extracellular protein factor from Streptococcus suis). In a serotype-specific fashion, this ralp3 epf gene block is integrated, most likely via transposition, into the eno sagA virulence gene block, which is present in all GAS serotypes. In GAS serotypes M1, M4, M12, M28, and M49 this novel discrete genetic region is therefore designated the eno ralp3 epf sagA (ERES) pathogenicity region. Functional experiments showed that Epf is a novel GAS plasminogen-binding protein and revealed that Ralp3 activity counteracts Nra and MsmR regulatory activity. In addition to the Mga and FCT regions, the ERES region is the third discrete chromosomal pathogenicity region. All of these regions are transcriptionally linked, adding another level of complexity to the known

  16. The Streptococcus pyogenes serotype M49 Nra-Ralp3 transcriptional regulatory network and its control of virulence factor expression from the novel eno ralp3 epf sagA pathogenicity region.

    Science.gov (United States)

    Kreikemeyer, Bernd; Nakata, Masanobu; Köller, Thomas; Hildisch, Hendrikje; Kourakos, Vassilios; Standar, Kerstin; Kawabata, Shigetada; Glocker, Michael O; Podbielski, Andreas

    2007-12-01

    Many Streptococcus pyogenes (group A streptococcus [GAS]) virulence factor- and transcriptional regulator-encoding genes cluster together in discrete genomic regions. Nra is a central regulator of the FCT region. Previous studies exclusively described Nra as a transcriptional repressor of adhesin and toxin genes. Here transcriptome and proteome analysis of a serotype M49 GAS strain and an isogenic Nra mutant of this strain revealed the complete Nra regulon profile. Nra is active in all growth phases tested, with the largest regulon in the transition phase. Almost exclusively, virulence factor-encoding genes are repressed by Nra; these genes include the GAS pilus operon, the capsule synthesis operon, the cytolysin-mediated translocation system genes, all Mga region core virulence genes, and genes encoding other regulators, like the Ihk/Irr system, Rgg, and two additional RofA-like protein family regulators. Surprisingly, our experiments revealed that Nra additionally acts as a positive regulator, mostly for genes encoding proteins and enzymes with metabolic functions. Epidemiological investigations revealed strong genetic linkage of one particular Nra-repressed regulator, Ralp3 (SPy0735), with a gene encoding Epf (extracellular protein factor from Streptococcus suis). In a serotype-specific fashion, this ralp3 epf gene block is integrated, most likely via transposition, into the eno sagA virulence gene block, which is present in all GAS serotypes. In GAS serotypes M1, M4, M12, M28, and M49 this novel discrete genetic region is therefore designated the eno ralp3 epf sagA (ERES) pathogenicity region. Functional experiments showed that Epf is a novel GAS plasminogen-binding protein and revealed that Ralp3 activity counteracts Nra and MsmR regulatory activity. In addition to the Mga and FCT regions, the ERES region is the third discrete chromosomal pathogenicity region. All of these regions are transcriptionally linked, adding another level of complexity to the known

  17. A multilevel prediction of physiological response to challenge: Interactions among child maltreatment, neighborhood crime, endothelial nitric oxide synthase gene (eNOS), and GABA(A) receptor subunit alpha-6 gene (GABRA6).

    Science.gov (United States)

    Lynch, Michael; Manly, Jody Todd; Cicchetti, Dante

    2015-11-01

    Physiological response to stress has been linked to a variety of healthy and pathological conditions. The current study conducted a multilevel examination of interactions among environmental toxins (i.e., neighborhood crime and child maltreatment) and specific genetic polymorphisms of the endothelial nitric oxide synthase gene (eNOS) and GABA(A) receptor subunit alpha-6 gene (GABRA6). One hundred eighty-six children were recruited at age 4. The presence or absence of child maltreatment as well as the amount of crime that occurred in their neighborhood during the previous year were determined at that time. At age 9, the children were brought to the lab, where their physiological response to a cognitive challenge (i.e., change in the amplitude of the respiratory sinus arrhythmia) was assessed and DNA samples were collected for subsequent genotyping. The results confirmed that complex Gene × Gene, Environment × Environment, and Gene × Environment interactions were associated with different patterns of respiratory sinus arrhythmia reactivity. The implications for future research and evidence-based intervention are discussed.

  18. Factors responsible for subclinical mastitis in cows caused by Staphylococcus chromogenes and its susceptibility to antibiotics based on bap, fnbA, eno, mecA, tetK, and ermA genes.

    Science.gov (United States)

    Bochniarz, M; Adaszek, Ł; Dzięgiel, B; Nowaczek, A; Wawron, W; Dąbrowski, R; Szczubiał, M; Winiarczyk, S

    2016-12-01

    The aim of this study was to recognize selected factors of virulence determining the adhesion of Staphylococcus chromogenes to cows' udder tissues in subclinical mastitis and to evaluate the susceptibility of this pathogen to antibiotics. The subjects of the study were 38 isolates of Staph. chromogenes from 335 samples of milk from cows with subclinical coagulase-negative staphylococci mastitis. Somatic cell count ranged between 216,000 and 568,000/mL of milk (average 356,000/mL of milk). We confirmed the ability to produce slime in 24 isolates (63.2%), and the ability to produce protease in 29 isolates (76.3%). In each slime-producing isolate, the bap gene was not found, and the fnbA and eno genes were not detected. In vitro tests showed that ceftiofur had the highest effectiveness against Staph. chromogenes (89.5% of susceptible isolates). Minimum inhibitory concentrations ranged from 0.06 to 2µg/mL for susceptible isolates. The minimum concentrations required to inhibit growth of 90 and 50% of the isolates for ceftiofur were at or below the cutoffs recommended by the Clinical and Laboratory Standards Institute (2 and 0.06µg/mL, respectively). A significant percentage of the isolates were susceptible to other β-lactam antibiotics: amoxicillin with clavulanic acid (84.2%) and ampicillin (81.6%). The lowest effectiveness among β-lactams was for penicillin (73.7% of susceptible isolates), and the minimum inhibitory concentration for penicillin ranged from chromogenes (71.1 and 63.2% of susceptible isolates, respectively). The genes tetK (6 isolates) and ermA (1 isolate) were also detected. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  19. Assessing Library Automation and Virtual Library Development in Four Academic Libraries in Oyo, Oyo State, Nigeria

    Science.gov (United States)

    Gbadamosi, Belau Olatunde

    2011-01-01

    The paper examines the level of library automation and virtual library development in four academic libraries. A validated questionnaire was used to capture the responses from academic librarians of the libraries under study. The paper discovers that none of the four academic libraries is fully automated. The libraries make use of librarians with…

  20. El cuento americano: Güeno-mapu

    Directory of Open Access Journals (Sweden)

    Gabriel Carvajal

    1966-02-01

    Full Text Available Helechos. Susurran como el abanico del pavo real. Ahí están. En grupos o hileras sobre la huella rojiza que va al caserío. Junto a la selva. Lejos, adentro, a donde solo llegan a ramonear los vahuales. En la traba de pellines, ulmos y araucarias, rosal silvestre y zarza levantada en altura de lianas y cañaveral.

  1. Analysis of automotive tire construction. Jidosha tire no kozo kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Ishihara, K. (Toyo Tire and Rubber Co. Ltd., Osaka (Japan))

    1993-06-15

    This paper introduces features and trends of analyzing performance and construction of automotive tires. Tires are demanded of high durability, high motion performance, good comfort performance for vibration and noise, and low fuel consumption performance. A feature of analyzing the construction is to execute a modelling assuming that a tire has air-rigid flexible structure and rubber materials show hyperelastic behavior, hypothesizing a strain energy density function. In addition, a tire is highly incompressible. Visco elasticity and anti-friction performance are also important points. Rubber and cord layers have elastic characteristic of three-dimensional perpendicular anisotropy as well as non-linearity with which characteristics change according to transformation. A structural analysis must cover from static analysis to steady dynamic analysis, non-steady dynamic analysis, and eigenvalue analysis. Thermal analysis of tires simulates phenomena by combining dynamical analysis with thermal analysis. Super-computers have now come to be used for formulating equilibrium equations using finite element methods, developing finite elements, and performing heat or visco elasticity analysis and applied analysis. 35 refs., 3 figs.

  2. El niño, oscilación del sur (ENOS, con relación a la transmisión de malaria, densidad y paridad de An. albimanus y An. darlingi (diptera: culicidae en dos regiones de Colombia

    Directory of Open Access Journals (Sweden)

    Ricardo Mantilla

    2000-02-01

    Full Text Available

    Una fuerte asociación ha sido registrada entre los incrementos en la transmisiónas forzadas por el fenómeno El Niño. Entre las posibles explicaciones para esta asociación está el efecto del clima sobre la dinámica de población de vectores, por ejemplo, generando cambios en la densidad y en las tasas de sobrevivencia de la población, y en la cantidad y calidad de sitios de reproducción, como también a través de cambios en el período de incubación extrínseco del parásito dentro del vector. Con el propósito de evaluar la influencia de ENOS sobre la densidad y paridad de Anopheles albimanus y An. darlingi, y su relación con la transmisión de malaria, se realizó un estudio longitudinal en Chocó y Casanare. En cada área se seleccionaron dos localidades y se realizaron muestreos entomológicos durante una semana cada mes, desde finales de 1997 hasta 1999. Este período cubrió los eventos El Niño 1997 -1998 y La Niña 1998 - 2000. En las localidades de Chocó se observó un importante incremento en el número de casos de malaria durante el evento ENOS, asociado con la temperatura. No se observó una asociación estadísticamente significativa entre los casos de malaria y la precipitación o la humedad relativa. La relación entre el incremento de malaria durante El Niño y las variables entomológicas no fue evidente. La densidad y paridad de ambas especies de vectores fluctuaron durante el período de estudio y no se encontró una asociación significativa entre estas variables y los factores climáticos como la temperatura. La precipitación y la humedad relativa. La densidad de larvas de An. albimanus fluctuó durante el estudio, y mostró altas densidades alrededor de julio - agosto. No se observó asociación entre la densidad de larvas con la densidad de adultos o las variables climáticas. El efecto del evento ENOS sobre las poblaciones de vectores

  3. Taenia saginata cysticercosis in Oyo State, Nigeria | Faleke ...

    African Journals Online (AJOL)

    http://dx.doi.org/10.4314/tv.v22i3.4562 · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact AJOL · News. OTHER RESOURCES... for Researchers · for Journals · for Authors · for Policy Makers ...

  4. Practical applications of superconducting technology; Chodendo gijutsu to sono oyo

    Energy Technology Data Exchange (ETDEWEB)

    Hoshino, M.; Yamamoto, K.; Urata, M. [Toshiba Corp., Tokyo (Japan)

    1995-11-01

    Remarkable progress has been made in superconducting technology recently. This paper describes the details and technical features of every cooling type of practical superconducting magnet (SCM), including the SCM for magnetic resonance imaging (MRI), SCM for semiconductor pulling devices, high-field SCM, SCM for magnetically confined plasma devices, and SCM for particle detectors. Commercial production of pool-boil-cooled SCMs has been realized by reducing helium evaporation and decreasing the frequency of helium pouring. The development of forced-cooled SCMs has made it possible to build large SCMs. Moreover, the development of the 4 K-GM refrigerator has enabled liquid-helium-free SCMs to be introduced. Since this type of SCM can be operated merely by turning on a switch, SCMs are expected to come into more widespread use. 7 refs., 1 fig.

  5. Helminthic infections among farmers in a rural community in Oyo ...

    African Journals Online (AJOL)

    Background: Helminthic infections are occupationally-related diseases which potentially undermine farmers' work capacity, productivity and life expectancy. These infections are usually under-reported among this group particularly in the rural areas. This study was carried out to determine the prevalence, pattern and factors ...

  6. Elemental Concentration of Harmattan Dust Sample in Iwo and Oyo ...

    African Journals Online (AJOL)

    ADOWIE PERE

    According to Balogun (1979), two sources of dust plumes were identified .... metals. Heavy metals are known to be harmful to human health if they are more than the recommended ... Chemical. Characterization and Source Apportionment of.

  7. Winning Strategies: A Case Study of Oyo State Lottery, Nigeria

    African Journals Online (AJOL)

    PROF. OLIVER OSUAGWA

    2014-06-01

    Jun 1, 2014 ... Keywords: Tickets, Lottery strategy, Winning numbers, Hypothesis testing, Historical ... Among all the games of ... different kinds of games are organized by ..... [1] Bradley, R.E. (2001), “Euler and the Genoese lottery”, [Online; ...

  8. The food of Parachanna obscura in Asejire reservoir, Oyo State ...

    African Journals Online (AJOL)

    . The weight of food ingested by P. obscura did not vary significantly (P > 0.05) with the size of fish, but with the type of diet consumed by the fish. Energy contents of ingested food by this fish also did not vary significantly with increase in fish ...

  9. Assessment of frog meat utilisation in Ibadan, Oyo state, Nigeria ...

    African Journals Online (AJOL)

    Frogs are among the most threatened species of wildlife in IUCN red list. Its utilisation in Ibadan, a major depot in western Nigeria was therefore conducted with the aim of assessing the forms and trend of use; and amongst others, reasons for frog meat consumption. Data for the study were collected through questionnaire, ...

  10. THREAT TO LIVESTOCK PRODUCTION AMONG WOMEN IN OYO ...

    African Journals Online (AJOL)

    AGROSEARCH UIL

    This study examines women farmers' perception on livestock involvement in road accident in ... this could be made possible through exchange of female goats among kilns and kiths in a ... bounded partly by Ogun State in the south, Kwara state in the North. ..... Realizing the promise and potentials of African agriculture.

  11. Phenotypic Characterization of the Bunaji Cattle Breed in Oyo State ...

    African Journals Online (AJOL)

    STD), body length (BLT), heart girth (HTG), height at withers (HTW), canon circumference (CCR), tail length (TLT), horn length (HLT) and ear length (ELT). Phenotypic traits such as dewlap, coat color, horn type, ear type, hump type and navel flap ...

  12. Flood occurrence and adjustment strategies in Oyo State: a case ...

    African Journals Online (AJOL)

    Floods are among the most dramatic forms of interaction between man and his environment, and they emphasize the limitations of man in his attempt to control the sheer force of nature. When they occur, whether in the developed or the developing world, they are always associated with heavy losses of life and property, ...

  13. Food Consumption Pattern in Ogbomoso Metropolis of Oyo State ...

    African Journals Online (AJOL)

    The study shed light on food consumption pattern in Ogbomoso Metropolis using Almost Ideal Demand System. Information on different classes of food consumed by the household was obtained using a multistage random technique. The result showed that demand for root and tubers and vegetables are elastic than ...

  14. Analysis of the Physicochemical Burden of Oyo State Fish Pond ...

    African Journals Online (AJOL)

    UCHWW was transparent, foamy, slimy, slightly smelly and no animal life was sighted in it. BDJWW was clear, no odour, animal life forms including fish and surface arthropods were sighted. Results of physicochemical parameters reported in the present study indicate contamination in OYSFP and fish produced there may ...

  15. Microbial Load on Smoked Fish commonly traded in Ibadan, Oyo ...

    African Journals Online (AJOL)

    PROF HORSFALL

    3Department of Fisheries Technology, Federal College of Animal Health and Production Technology Moor Plantation, .... other ready to eat food in Nigeria thus the need for this ..... Studies on the effect of processing methods on the ... microbiological food poisoning and its ... Olutiola, PO; Famurewa, O; Sonntag, HG (1991).

  16. Determinants of Child Mortality in Oyo State, Nigeria

    African Journals Online (AJOL)

    Toshiba

    these deaths occurred in just five countries namely, India, Nigeria, the. Democratic Republic of .... the impact health has on economic growth. It was observed that .... poverty shows a positive relationship with child mortality. The result however ...

  17. Spatial Modelling of Road Traffic Accidents in Oyo State, Nigeria ...

    African Journals Online (AJOL)

    ... our technological era, whose list of victims insidiously grows longer day by day. ... common as if this was a price that the society has to pay for the right to travel. ... All other things being equal, Local Governments Areas with larger residential ...

  18. USE OF ICT IN SELECTED LIBRARIES IN IBADAN, OYO STATE ...

    African Journals Online (AJOL)

    Ibadan were at the developmental stage in the use of ICT for processing ... education and human capacity building, there are significant patterns of change ... environment has made it important for libraries so strive to improve their quality of.

  19. Occurrence of Klebsiella Species in Cultured African Catfish in Oyo ...

    African Journals Online (AJOL)

    Over the years, the increase in population, incomes, and demograph has lead to the increase in the consumption of fish as a result of its nutritional values. Clarias gariepinus is the most cultured fish species in Nigeria and attracts significant economic value making it a species of interest. Fish is capable of habouring ...

  20. Composición y abundancia de artrópodos epígeos del Parque Nacional Llanos de Challe: impactos del ENOS de 1997 y efectos del hábitat pedológico Abundance and composition of epigean arthropods from Llanos de Challe National Park: impacts of ENSO-1997 and effects of the pedological habitat

    Directory of Open Access Journals (Sweden)

    JORGE CEPEDA-PIZARRO

    2005-12-01

    Full Text Available Mediante el uso de trampas de intercepción, se estudió el efecto de la precipitación y el tipo de hábitat sobre la denso-actividad del ensamble de artrópodos epígeos _en particular Tenebrionidae_ del Parque Nacional Llanos de Challe. Este parque está ubicado en el desierto costero transicional de Chile, en la III Región de Atacama. Los muestreos se realizaron durante tres días por mes (septiembre, octubre y diciembre en el período de máxima actividad biológica del sistema y en los años 1989 (año no-ENOS seco, 1997 (año ENOS intenso y 2000 (año no-ENOS húmedo. En las comparaciones se utilizaron dos sitios pedológicamente contrastantes: un hábitat dunario costero y un hábitat pedregoso interior. Se registró la presencia de 15 órdenes de Arthropoda. Los hexápodos constituyeron > 95 % del total de los especímenes capturados (9.065 individuos, siendo Collembola (36,1 % y Coleoptera (29,8 % los órdenes con mayor representatividad numérica. El número de órdenes con representantes activos varió ligeramente entre años: 13 órdenes se registraron en 1989 (44 % de precipitación bajo el promedio, 15 en 1997 (443 % sobre el promedio y 11 en 2000 (52 % sobre el promedio. El efecto del evento ENOS se reflejó claramente en la contribución numérica en la mayoría de los taxa registrados. Aunque más sutilmente, este efecto también se reflejó en la composición del ensamble de taxa dominantes y entre hábitat pedológicos, particularmente con Tenebrionidae y Formicidae. Especialmente en las dunas costeras, Tenebrionidae dominó claramente el ensamble de artrópodos epígeos, siendo Gyriosomus Guérin-Méneville el género más diverso y abundante. La dominancia de Gyriosomus plantea un conjunto de interrogantes respecto de su nivel de endemismo, diversidad y distribución de sus especies, y el papel funcional de estas en el ecosistema estudiadoBy using pitfall traps, the effects of rainfall and habitat type on the denso

  1. Space tourism; next goal of rocketry; Uchu eno ryokaku yuso

    Energy Technology Data Exchange (ETDEWEB)

    Inatani, Y. [Institute of the Space and Astronautical Science,Tokyo (Japan)

    2000-01-05

    As to the space travel to be conducted as business, the paper presented the results of the study being made to extract subjects. The single-stage space transport system which can be completely reused is said to be realized by much more weight reduction in airframe structure and improvement of propulsion performance, judging from the present technology standard. The reason the present form of rocket has to be reformed is that the cost needed to put a load of 1kg into orbit around the earth is higher in order of 1 million yen than those of other vehicles. Because the rocket is disposable, it is difficult to make an enormous cost reduction, and therefore, it is necessary to realize the same operation form as that adopted to airplane. The price of tickets for space travel rationally determined by the demand side is between 1.5-2.0 million yen. The annual sales are estimated at approximately 1.3 trillion yen on the market. When calculating this as business, it is necessary to reduce the transportation cost from 1,000,000 yen to 90,000-10,000 yen. A conceptual design was made of a space travel standard airframe 'Kanko-maru.' (NEDO)

  2. Meedikud loodavad rahumeelsele leppele / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2007-01-01

    Tervishoiutöötajate kutseliitude esindajad võtsid väljakuulutatud streigihoiatuse maha lootuses, et kokkulepe meditsiinitöötajate miinimumtunnitasu osas võib sõlmida rahulikul teel. Arvamust avaldab Haiglate Liidu juhatuse esimees Urmas Sule

  3. President istutas Torisse tamme / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2007-01-01

    President Toomas Hendrik Ilves osales Toris Eesti sõjameeste mälestuskirikus traditsioonilisel vabadusvõitluse mälestusele pühendatud jumalateenistusel ja istutas kiriku kõrvale prominentide parki tamme. Varem on sellesse parki tammepuu istutanud president Arnold Rüütel, 20. augusti klubi, endine kaitseväe juhataja Aleksander Einseln ja peapiiskop Andres Põder

  4. President Ilves kohtus õpilaste ja kaitseliitlastega / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2007-01-01

    President Toomas Hendrik Ilves külastas mitteametlikul visiidil 9.11.2007 Pärnu Sütevaka humanitaargümnaasiumi ja Kaitseliidu Pärnumaa malevat. Sütevaka humanitaargümnaasiumis kuulas president muusikakanali MTV Europe parima uustulnuka auhinna võitnud poistebändi Bedwetters esinemist ning osales lõpuklassi ühiskonnaõpetuse tunnis, rääkides kooli loosungist "Vabadus, loovus, vastutus" inspireeritult vabadusest ja vastutusest

  5. Feminismo e/no pós-colonialismo

    Directory of Open Access Journals (Sweden)

    Deepika Bahri

    2013-11-01

    Full Text Available http://dx.doi.org/10.1590/S0104-026X2013000200018 Neste artigo, a autora discorre sobre a relação entre feminismo e pós-colonialismoa partir dos conceitos-chave nos estudos pós-coloniais, salientando as premissas, os métodose as tensões dessa aliança, bem como os desafios entre os feminismos “ocidental” e “póscolonial”no contexto da globalização.

  6. Influence of spectral solar radiation to the generating power of photovoltaic module; Taiyo denchi shutsuryoku eno taiyoko supekutoru eno eikyo

    Energy Technology Data Exchange (ETDEWEB)

    Minaki, S.; Ishihara, Y.; Todaka, T.; Harada, K. [Doshisha University, Kyoto (Japan); Oshiro, T.; Nakamura, H. [Japan quality Assurance Organization, Tokyo (Japan)

    1997-11-25

    As to the influence of spectral solar radiation to generating power of solar cells, a study was conducted from the aspects of season, time zone, intensity of solar radiation, etc. In the study, spectral responsive variation correction coefficients were introduced as evaluation values expressing the influence of spectral solar radiation. For the spectral distribution, an all sky spectral pyranometer by wavelength was used, and data were used which were obtained in the measurement in experimental facilities of the solar techno center. Concerning solar cell relative spectral sensitivity values, used were relative spectral sensitivity values of monocrystal and amorphous standard solar cells to the short-circuit current. Spectral response variation correction coefficients are coefficients correcting variations in conversion efficiency of solar cells due to changes in the spectral distribution. The changes of spectral responsive variation correction coefficients were studied using data obtained during April 1994 and March 1996. As a result, it was found that the coefficients showed large changes in summer and small ones in winter and that amorphous solar cells indicate this trend conspicuously. 3 refs., 6 figs., 3 tabs.

  7. Analysis of stress distribution of timing belts by FEM; Yugen yosoho ni yoru timing belt oryoku kaiseki (belt code oryoku bunpu kaiseki hokoku)

    Energy Technology Data Exchange (ETDEWEB)

    Furukawa, Y; Tomono, K; Takahashi, H; Uchida, T [Honda R and D Co. Ltd., Tokyo (Japan)

    1997-10-01

    A model of the belt analyzed by-ABAQUS (: a general nonlinear finite element program) successfully confirmed the mechanism that generates the belt cord stress. A quite good agreement between experimental and computed results for the stress distribution of the belt cord. It is found that maximum stress of the cords occurs near the root of the tooth by calculation, where the belt cords break off. 3 refs., 9 figs.

  8. Creep analysis and torsional vibration analysis of cable-stayed bridges with two edge composite girders; Nishuketa gosei kozo shachokyo no creep kaiseki to nejiri shindo kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Hoshino, M. [Nihon University, Tokyo (Japan). College of Science and Technology

    1996-07-21

    This paper describes the creep analysis and torsional vibration analysis of cable-stayed bridges with two edge composite girders. The girder is composed of the concrete slab and the steel girder. I-girders are placed at both edges of the profile. Such a type of bridge was investigated. As the stress migrates by the creep of concrete slab, it is necessary to evaluate the influence of this creep precisely in designing. In the analysis, the composite girder was expressed not by the single member, but by the binary member consisting of concrete member and steel member. Two methods were employed, i.e., method A in which both members are connected by the rigid body beam and method B in which the profile of concrete is converted into the profile of steel. The method A provided better accuracy, but the method B was often sufficient. Torsional rigidity of the open profile structure was much smaller than that of the box profile. As the torsional natural frequency was low, proper torsional vibration analysis was indispensable especially from the viewpoint of wind resistance. Two methods were employed, which utilize the vibration analysis method for general space frame structures. Results of both methods were agreed mutually, but the second method provided better calculation efficiency. 10 refs., 9 figs., 6 tabs.

  9. Analysis of current distribution in a large superconductor; Chodendo dotai nai no denryu bunpu kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Hamajima, K.; Alamgir, A.K.M.; Harada, N.; Tsuda, M. [Yamaguchi Univ., Yamaguchi (Japan); Ono, M.; Takano, H. [Toshiba Corp., Tokyo (Japan)

    2000-04-25

    An imbalanced current distribution is often observed in cable-in-conduit (CIC) superconductors, which are composed of multistaged, triplet type sub-cables, and deteriorates the performance of the coils. Therefore, it is very important to analyze the current distribution in a superconductor and find out methods to obtain a homogeneous current distribution in the conductor. We apply a magnetic flux conservation in a loop contoured by electric center lines of filaments in two arbitrary strands located on adjacent layers in a coaxial multilayer superconductor, and then analyze the current distribution in the conductor. A generalized formula governing the current distribution can be described as explicit functions of the superconductor construction parameters, such as twist pitch, twist direction and radius of each layer. It is shown that we can obtain a homogeneous current distribution using this fundamental formula, which is a function of the twist pitches of layers. Moreover, it is demonstrated that we can control current distribution in the coaxial superconductor. (author)

  10. Seismic traveltime tomography by use of gridpoints discritization; Koshitenho ni yoru danseiha tomography kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Hirai, T; Watanabe, T; Sassa, K [Kyoto University, Kyoto (Japan). Faculty of Engineering

    1996-05-01

    Efforts were made to enhance analytical precision and stabilize the results in seismic traveltime tomography by use of a method wherein the velocity distribution is expressed as a continuous function interpolated by parameters respectively assigned to the gridpoints. In this method, the slowness data are regarded as the parameters respectively assigned to the gridpoints, and the slowness value at a given point is determined after interpolation by the gridpoints surrounding the said point. A method based on the variation principle was used for ray tracing. As the result, it was confirmed that this method determines the ray path and traveltime with high precision. A method of least squares using Lagrange`s multiplier was applied for inversion. Comparison was made between the use of cells and the use of gridpoints in the results of inversions performed for an inclined 4-layer structure model, when it was found that the values involving the boundaries between layers, inclinations of the layers, and velocities of seismic waves are ambiguous with the cells while those with the gridpoints are reconstructed roughly correctly. 5 refs., 7 figs., 1 tab.

  11. Performance analysis in Japanese field test program; Field test data kara no chiiki hatsuden kaiseki hoho

    Energy Technology Data Exchange (ETDEWEB)

    Sugiyama, H.; Kurokawa, K.; Uchida, D. [Tokyo University of Agriculture and Technology, Tokyo (Japan); Otani, K.; Sakuta, K.; Tsuda, I. [Electrotechnical Laboratory, Tsukuba (Japan); Oshiro, T.; Sakamoto, K. [Japan Quality Assurance Organization, Tokyo (Japan)

    1997-11-25

    Power generation characteristics are investigated using data collected in photovoltaic power generation field tests being undertaken by NEDO (New Energy and Industrial Technology Development Organization). The photovoltaic power generation system performance is evaluated by examining loss factors leading to degradation in system performance, with weather conditions such as variation in insolation and air temperature, inverter performance, and shadows cast by surrounding buildings taken into consideration. As the result, it is found that the important loss factors are degradation in module performance due to elevated temperature, drift in the maximum output control, degraded inverter performance due to input power variation, effect of shadows, etc. It is learned that system is greatly affected by degradation in module performance due to increased temperature in summer and by shadows in winter, the two being responsible for the output coefficient dropping to approximately 75% throughout the year. The output coefficient frequency distribution charts for the 75 test sites confirm that the rate is as low as 70-80% at many sites. As for the system operating time, it tends to be longer in West Japan where the annual insolation rate is higher. 3 refs., 10 figs.

  12. Analysis of bending process using forming simulation; Seikei simulation ni yoru press niji seikei kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Hamaguchi, T; Ogawa, T; Tamai, H [Mazda Motor Corp., Hiroshima (Japan)

    1997-10-01

    FEM simulation system is becoming an effective tool in the production engineering, especially in the evaluation of press formability. We have been applying it to the evaluation of defect phenomena, such as breakage and wrinkling, which occur in the drawing process to produce auto body parts. We tried a new application which treat dimensional precision and the other defect in the flanging or bending process after trimming. In this paper, we introduced the result of development and an example applied in the analysis. 1 refs., 8 figs.

  13. Analysis of levitation characteristics of radial-type superconducting magnetic bearings; Rajiarugata chodendojikijikuju no fujotokusei kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Fukuyama, H.; Takizawa, T. [NSK Ltd., Kanagawa (Japan)

    1999-11-25

    In the design of a large-scale flywheel. load capacity and bearing constants (i.e. spring and damping constants) should be accurately calculated. In this report, a newly developed analysis method for radial-type superconducting magnetic bearings (SMBs) composed of several couples of magnet rings and magnetic material spacers is described. The analysis based both on electromagnetic FEM of the magnetic field and the 2-dimensional Bean model for analysis of the magnetization of type-2 superconductors. To obtain accurate magnetization hysteresis that reflects the complex magnetic fields, a superconductor is meshed into cells and then the electromagnetic force between the magnetic fields of magnetics and the magnetization of the superconductor are calculated. Recently, computer programs which can calculate the axial load capacity of radial-type SMBs have been developed. Furthermore, programs which can calculate bearing constants are close to being completed. Calculated results on axial load capacity showed good agreement with the experimental results. (author)

  14. Crack coke in layer heat transfer analysis; Kiretsu no shinten wo tomonau kokusu sonai dennetsu kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Aoki, Hideyuki [Tohoku University, Miyagi (Japan)

    1999-03-05

    The research method heat transfer process by physical change of the coke by heat transfer from furnace wall in the retorting of coal seam filled in coke oven and flow of the gas is very complicated chamber oven style, and it does not become clear. For the purpose of the elucidation of in layer crack generation and progress mechanism, he is (1) The expansion of the softening cohesive layer. (2) Programming rate dependence of the heat. Mechanical property value on coal seam and semi- coke layer in the retorting. (3) The creep property of softening cohesive layer and semi- coke layer. (4) The setting of crack growth condition of stress intensity factor in crack tip and fracture property value of the coke by the comparison. (5) By considering the radiative heat transfer in the crack, coke in layer thermal stress analysis was carried out. The validity of these analytical result it was confirmed by the comparison with the experimental result of crack growth. Deformation behavior in the small dry distillation furnace, and crack growth mechanism in the coke layer became clear, and the prediction of the stress as micro-crack cause of generation of heating surface side coke surface and inside became possible. The numerical analysis method of the above crack growth mechanism greatly contributes to the prediction of dry distillation heating requirement and grain size of coke lump which is an index to the coke quality. Heat on material process which is accompanied by the solidification. Contraction from the softening and material migration phenomenon have been clarified by the creative research method, while this research is directly useful for energy saving of pig ironmaking process of becoming one of the ringleaders of the CO{sub 2} generation. (translated by NEDO)

  15. Analysis of impact resistance of composite fan blade. Fukugozai fan blade no taishogekisei no kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Miyachi, T; Okumura, H; Otake, K; Sofue, Y [Japan Society for Aeronautical and Space Sciences, Tokyo (Japan)

    1992-01-05

    Numerical analysis of impact response was carried out when a bird strike was simulated to study the applicability of fiber reinforced composite material to fan blades for turbo-fan engines. The validity of the numerical analysis was verified by comparing the analyzed results with impact tested results of a fan-blade model of Ti-alloy. The impact resistance was studied by applying this method to fan blades of composite materials such as carbon fiber, epoxy resin and carbon-silicate fiber reinforced Ti-alloy. The finite element method was used for the analysis by dividing the model into triangular flat elements. The relation between the impact load, the deformation of blade and the strain, the natural frequency characteristics, the elastic modulus and hetrogeneity of blade were considered to analyze the impact response. The impact load by the strike of 1.5 lbs bird is very severe to the fan blades for turbo-fan engines having the thrust of 5 ton class. 23 refs., 23 figs., 3 tabs.

  16. Fault structure analysis by means of large deformation simulator; Daihenkei simulator ni yoru danso kozo kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Murakami, Y.; Shi, B. [Geological Survey of Japan, Tsukuba (Japan); Matsushima, J. [The University of Tokyo, Tokyo (Japan). Faculty of Engineering

    1997-05-27

    Large deformation of the crust is generated by relatively large displacement of the mediums on both sides along a fault. In the conventional finite element method, faults are dealt with by special elements which are called joint elements, but joint elements, elements microscopic in width, generate numerical instability if large shear displacement is given. Therefore, by introducing the master slave (MO) method used for contact analysis in the metal processing field, developed was a large deformation simulator for analyzing diastrophism including large displacement along the fault. Analysis examples were shown in case the upper basement and lower basement were relatively dislocated with the fault as a boundary. The bottom surface and right end boundary of the lower basement are fixed boundaries. The left end boundary of the lower basement is fixed, and to the left end boundary of the upper basement, the horizontal speed, 3{times}10{sup -7}m/s, was given. In accordance with the horizontal movement of the upper basement, the boundary surface largely deformed. Stress is almost at right angles at the boundary surface. As to the analysis of faults by the MO method, it has been used for a single simple fault, but should be spread to lots of faults in the future. 13 refs., 2 figs.

  17. Two-dimensional inversion of MT (magnetotelluric) data; MT ho no nijigen inversion kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Ito, S; Okuno, M; Ushijima, K; Mizunaga, H [Kyushu University, Fukuoka (Japan). Faculty of Engineering

    1997-05-27

    A program has been developed to conduct inversion analysis of two-dimensional model using MT data, accurately. For the developed program, finite element method (FEM) was applied to the section of sequential analysis. A method in which Jacobian matrix is calculated only one first time and is inversely analyzed by fixing this during the repetition, and a method in which Jacobian matrix is corrected at each repetition of inversion analysis, were compared mutually. As a result of the numerical simulation, it was revealed that the Jacobian correction method provided more stable convergence for the simple 2D model, and that the calculation time is almost same as that of the Jacobian fixation method. To confirm the applicability of this program to actually measured data, results obtained from this program were compared with those from the Schlumberger method analysis by using MT data obtained in the Hatchobara geothermal area. Consequently, it was demonstrated that the both are well coincided mutually. 17 refs., 7 figs.

  18. Data processing for the fluid flow tomography method; Ryutai ryudo den`iho no data kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Ushijima, K; Mizunaga, H; Tanaka, T [Kyushu University, Fukuoka (Japan). Faculty of Engineering; Hashimoto, K [Kyushu Electric Power Co. Inc., Fukuoka (Japan)

    1997-05-27

    An automatic measurement system by means of conductive potential and self-potential methods (fluid flow tomography method) has been developed to measure the change of geothermal steam fluid during production and injection. For the fluid flow tomography method, the four-electrode configuration of the conductive potential method is adopted using the casing pipe of well as a current source. A lot of potential receiving electrodes are connected to the earth, preliminarily. The surface potential profile is measured, which is formed during the injection and production of the fluid through the well. Artificial and spontaneous potential profiles were continuously measured using this system during the hydraulic crushing tests at the test field of hot dry rock power generation at Ogachi-machi, Akita Prefecture. As a result of inversion analysis of self-potential data using a four-layer structural model of specific resistance, it was observed that the fluid injected at the depth of 711 m in the borehole permeated into the depth between 700 and 770 m in the south-eastern part of the well, and that the fractures propagated into the deeper part, gradually with the progress of hydraulic crushing test. 3 figs.

  19. Reservoir characterization using artificial neural network; Neural network wo mochiita choryuso tokusei kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Shimada, N; Kozawa, T [Japan National Oil Corp., Tokyo (Japan); Nishikawa, N; Tani, A [Fuji Research Institute Corp., Tokyo (Japan)

    1997-05-27

    Neural network is used for the prediction of porosity and permeability using logging data as reservoir characteristics, and the validity of this method is verified. For the prediction of reservoir characteristics by the use of seismic survey data, composite seismic survey records obtained by density logging and acoustic logging are used to experiment the prediction of porosity and permeability continuous along lines of wells. A 3-output back propagation network is used for analysis. There is a possibility that this technique when optimized will improve on prediction accuracy. Furthermore, in the case of characteristics mapping, 3-dimensional seismic data is applied to a carbonate rock reservoir for predicting spatial porosity and permeability. This technique facilitates the comprehensive analysis of core data, well data, and seismic survey data, enabling the derivation of a high-precision spatial distribution of reservoir characteristics. Efforts will continue for further improvement on prediction accuracy. 6 refs., 7 figs., 3 tabs.

  20. Simulation for thermal response of a spherical LPG tank; Kyukei LPG chozo tanku no netsuoto kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Hsi-jen; Lin, Mann-hsing; Chao, Fu-yuan [Tamkang University, Tamsui (Taiwan). Department of Chemical Engineering

    1999-03-05

    Liquefied petroleum gas (LPG) is a very important fuel and chemical feed stock as well; however, the hydrocarbon has been involved in many major fires and explosions. One of these accidents is boiling-liquid, expanding-vapor explosion (BLEVE). It is a phenomenon that results from the sudden release from confinement of a liquid at a temperature above its atmospheric-pressure boiling point. The sudden decrease in pressure results in the explosive vaporization of a fraction of the liquid and a cloud of vapor and mist with the accompanying blast effects. Most BLEVEs involve flammable liquids, and most BLEVE releases are ignited by a surrounding fire and result in a fireball. The primary objective of this paper is to develop a computer model in order to determine the thermal response of a spherical LPG tank involved in fire engulfment accidents. The assessment of the safety spacing between tanks was also discussed. (author)

  1. Numerical analysis on flows in supersonic air intakes. Choonsoku kuki toriireguchi no nagare no suchi kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Shimada, T.; Tamura, N.; Sekino, N.; Tsujimura, N. (Nissan Motor Co. Ltd., Tokyo (Japan))

    1992-06-25

    By applying computational fluid dynamics (CFD) to a flow in the supersonic air intake of rocket, appropriateness of computational result was confirmed from a comparison with the wind tunnel test result. In order for the air intake type rocket to heighten the combustion efficiency of fuel and air, it is important to possibly minimize the total pressure loss of air which has been taken in and maintain the air flow rate. A numerical analysis was made through modeling the sectional shape of wind tunnel test body and analyzing the two-dimensional flow by Reynolds-averaged Navier-Stokes equations. The computational result of analysis coincided well with the pressure measurement result in wind tunnel test. Having elucidated the main factors of total pressure loss in a two-dimensionally curved flow passage, the CFD computation gave a possibility that the total pressure loss is considerably low against that passage if improved in shape. If simultaneously used with a characteristic curve method, the CFD computation made it possible to optimize the pressure recovery characteristics in the axially symmetric air intake. The CFD can be expected to be an effective method of designing the basic shape of supersonic air intake. 9 refs., 14 figs.

  2. Analysis of appearance of softness for interior plastic parts; Naiso jushi buhin no soft kan kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Kubota, T; Wada, T; Matsuda, M [Toyota Central R and D Laboratories Inc., Aichi (Japan); Nagata, M; Maeda, M [Toyoda Gosei Co. Ltd., Aichi (Japan)

    1997-10-01

    The Appearance of softness was evaluated using the paired comparison method for steering wheel pads. Many kinds of physical quantities of sample pads, such as the depth of wrinkles, surface roughness and gloss, were measured. Correlations between the appearance of softness and the physical quantities were analyzed. As a result, this appearance of softness was found to be characterized by four factors, the depth and slope of wrinkles, gloss and lightness. 3 refs., 4 figs., 4 tabs.

  3. Genetic manipulation of woody plants and its applications. Rinboku no idenshi sosa to sono oyo

    Energy Technology Data Exchange (ETDEWEB)

    Ebinuma, H. (Jujo Paper Co. Ltd., Tokyo (Japan))

    1992-06-01

    The advance of plant biotechnology has been further accelerated by the development of the new epoch-making technique typified by the DNA amplification using the PCR (polymerase chain reaction) method. In the application of plant biotechnology to trees, the introduction of useful genes into genetically elite trees and short-period mass propagation of recombinants by micropropagation are considered to be rational strategies. In the utilization of recombinants, non-edible industrial product materials such as trees are considered to pass the safety standards more easily and also to be profitable. This paper discusses the possibilities of tree recombinants, the imparting of disease-resistance to elite trees and the biosynthetic control of lignin. The paper introduces a topic that the imparting of disease-resistance to elite trees is in a stage of transference to experiments of recombinants in a closed-system greenhouse by the construction of the crown gall resistant gene and the establishment of the gene introduction system into crossed populus sieboldii miquel. 19 refs., 4 figs.

  4. Fast Food Consumption Pattern among Youth in Ogbomoso Metropolis of Oyo State, Nigeria

    OpenAIRE

    Ogunniyi Laudia Titilola; Adepoju Adenike Adebusola; Olagunju Funke Iyabo; Akinola Oluseyi Yewande

    2013-01-01

    Fast food has become a prominent feature of diet and has grown into a dominant dietary pattern among youth worldwide. It is difficult to escape noticing the colourful edifice and bill boards of these food outlets, one is probably just around the corner of your street. Mr Biggs, Tastes Fried Chicken, Sweet Sensation, Big Treat, Favourite etc. Due to competitive nature of the market many of the food outlets market have started to blend their menus with African cuisines like Pounded Yam, Amala, ...

  5. HIV/AIDS in Oyo State, Nigeria: analysis of spatial pattern of ...

    African Journals Online (AJOL)

    This is in addition to Promiscuity and multiple sexual partner practices which spread the pandemic. The study however defined policy direction for government by churning out a number of recommendations which can help control the spread of the pandemic and care for the victims in the study area. Keywords: HIV/AIDS ...

  6. Determinants of Farmers' Access to Micro-Credit in Oyo State, Nigeria

    African Journals Online (AJOL)

    ... (2 from 4 Local Government Areas in each agricultural zone) were selected. ... Z-score test of significance, Tobit regression model was used to capture the expected ... Result of the Tobit probability regression analysis also revealed that age(X1) ... All the significant variables except Age (X1) were positively correlated to ...

  7. Resistivity tomography-basic concepts and its application. Hiteiko tomography no kiso to oyo

    Energy Technology Data Exchange (ETDEWEB)

    Shima, H

    1990-12-31

    In this paper, principles and characteristics of resistivity tomography are outlined, and its application examples are described. Resistivity tomography is a technology to measure electric potential of many electrodes placed on the earth {prime} s surface or in the well and to analyze the resistivity distribution in the objective area. Arrangement of electrodes (current electrodes and potential electrodes) is determined taking account of the sensitivity distribution. Also, measurements need to be done not only between the surface and a borehole and between boreholes, but also along the wall of a borehole. After the measured data are corrected according to the influence of topography, the initial model is revised repeatedly with the Alpha Center method, and then, resistivity distribution maps are obtained. As an example of field application of resistivity tomography, a geological survey using three boreholes at the scheduled construction site for a dam is described. In this survey, distribution conditions of surface soil, gravel, and andesite were confirmed, and the results almost agreed with the results of seismic tomography. Moreover, another survey with resistivity tomography was carried out at the test site of hot dry rock power generation in Yamagata Prefecture. There, conductive solution was injected from the borehole after hydraulic fracturing, and cracking conditions of rocks were investigated. 28 refs., 21 figs., 1 tab.

  8. The Impact of Infertility on Infertile Men and Women in Ibadan, Oyo ...

    African Journals Online (AJOL)

    Erah

    African Journal of Reproductive Health Vol 13 No 3 September 2009. 85. ORIGINAL RESEARCH ARTICLE. The Impact of Infertility on ... reproductive health strategy does not seek to reduce the prevalence or impact of infertility but instead ..... will turn into a snake and go inside the cupboard and eat the soup, it nearly broke.

  9. Risks mitigation in the poulty sub-sector in Oyo state: A case study of ...

    African Journals Online (AJOL)

    Risks and uncertainties associated with agricultural business have to a great extent undermined the productivity and sustainability of the agricultural sector by reducing the availability of institutional credit for investment in agriculture. Hence, this article examined the risks mitigating functions of the Nigerian Agricultural ...

  10. An evaluation of Oyo state library board in meeting the information ...

    African Journals Online (AJOL)

    The study is aimed at promoting the utilization and effectiveness of public library in Ibadan by secondary school students to enhance their academic perfor mance and exposure to international events. The study adopted descriptive survey research design. Questi onnaire was the main instrument for data collection, other ...

  11. The State of Reading in Selected Secondary Schools in Oyo State ...

    African Journals Online (AJOL)

    Nekky Umera

    Introduction ... culture, lack of reading materials and other socio-economic, have been ... One of the fundamental objectives of education is to produce a literate .... carry out the study, appropriate questions that captured the issues that are.

  12. Non-meritocratic Factors and the Recruitment Process in Oyo State ...

    African Journals Online (AJOL)

    to explore the subject matter, which has been long enduring, and, to test the feasibility .... civil servants in different ministries who have undergone the recruitment and selection ... Male. Female. 197. 153. 56.6. 43.4. Marital status. Single. Married. Widowed .... “In the typical Nigerian society, there is no place that such things.

  13. Space for Convenience Planning and Academic Performance of Secondary School Students in Oyo State, Nigeria

    Science.gov (United States)

    Yakubu, Suleman

    2017-01-01

    Every secondary school leaver is expected to be able to seek and gain admission into institutions of higher learning, both locally and internationally. However, this has become unattainable as a result of the poor academic performance seen in senior secondary school examinations; the quintessential example being the West African Senior School…

  14. Effects of flood on farmers in peri-urban area of Ibadan, Oyo state ...

    African Journals Online (AJOL)

    One of the commonest environmental hazards threatening food security now in Nigeria is flood. The study therefore investigated the effects of flood on farmers in peri – urban areas of Ibadan. Using a snow ball research method, 60 farmers were selected from the six local governments in the peri – urban areas of Ibadan and ...

  15. The State of Reading in Selected Secondary Schools in Oyo State ...

    African Journals Online (AJOL)

    school are left to the discretion of students. Among the teachers who give attention to reading, we found a majority of them who failed to give students the necessary motivation to strengthen their interest in reading. It was also found out that most school heads contributed to the poor reading culture of the students by their ...

  16. Evaluation of Aeromagnetic Data of Ilesha Area of Oyo State Nigeria ...

    African Journals Online (AJOL)

    ADOWIE PERE

    These methods were used to process and analyse the data so as to generate the depth to magnetic sources as .... structural index, which defines the geometry of the ... Shallow sources. (km). Average. (km). Less predominant location. Deeper.

  17. Parental and Related Factors Affecting Students' Academic Achievement in Oyo State, Nigeria

    OpenAIRE

    Oladele K. Ogunsola; Kazeem A. Osuolale; Akintayo O. Ojo

    2015-01-01

    Many factors influence the educational outcome of students. Some of these have been studied by researchers with many emphasizing the role of students, schools, governments, peer groups and so on. More often than not, some of these factors influencing the academic achievement of the students have been traced back to parents and family; being the primary platform on which learning not only begins but is nurtured, encouraged and developed which later transforms to the perfor...

  18. Development of application technology of ultrasonic wave sensor; Choonpa sensor oyo gijutsu no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    Hosoya, H; Hikita, N; Sasaki, H; Kore, H [Mazda Motor Corp., Hiroshima (Japan)

    1997-10-01

    We have developed parking assist system, which informs a driver the closing point and distance to the objects such as other vehicle, wall and pole around the own vehicle at parking area and makes parking maneuverability easy. This system is based on the range detection technology using ultrasonic wave sensor. We have improved the detecting ability in short range of about 20cm by reducing the reverberation of transmitting wave signal and controlling sensitivities of signal intensity and threshold line. We will show mainly the improvement of short range detection of ultrasonic wave sensor, and briefly the performance of parking assist system. 1 ref., 14 figs., 1 tab.

  19. Causes of poverty: Voices of the rural poor from Oyo State, Nigeria ...

    African Journals Online (AJOL)

    This paper argues that poverty is multidimensional in nature and that its causes are multifaceted and extremely complex. It contends that poor people's own views of their descent into poverty are fundamental to understanding the complexity of poverty and to devising appropriate policy interventions that may lead to ...

  20. GENDER AND COST EFFICIENCY IN MAIZE PRODUCTION IN OYO STATE OF NIGERIA

    Directory of Open Access Journals (Sweden)

    Ogunniyi Titi Laudia

    2009-12-01

    Full Text Available The issues of gender in smallholder farmers in Nigeria have been widely debated in terms of marginalization in main input leaving out the efficient use of these resources. In this paper, an empirical assessment of smallholder cost efficiency and its determinants using stochastic cost frontier function was conducted. In addition, regression and paired sample t-test were used to examine the determinants of efficiency. The results indicates that labour is an important factor of production for both male and female farmers and that female are more cost inefficient than their male counterparts The study concluded that there should be a review of the agricultural policy that will address the existing gender bias in assessing agricultural inputs.

  1. The determinants of the demand and supply of eggs in Ibadan, Oyo ...

    African Journals Online (AJOL)

    The hypothesis that the presence of broiler enterprise on the farm limits the quantity of eggs supplied was upheld, so also was the hypothesis that the income elasticity of demand for eggs was positive. Layers mash was found to be highly price elastic; the own price elasticity of demand for eggs was found also to be elastic ...

  2. Effect of Malaria on Rural Households' Farm Income in Oyo State ...

    African Journals Online (AJOL)

    Samuel Olaleye

    procedure was employed for the research survey in which the first level of stratification ... use of modern preventive measures (12%), poor sanitary conditions, and large ... and who constitute over 65 percent of the nation's ... pregnant women, young children, migratory .... analysis shows that the average age of the farmers.

  3. HIV / AIDS And The Socio – Economic Status Of Victims In Oyo State ...

    African Journals Online (AJOL)

    Owing to the ferocious spread of HIV / AIDS and the soaring cases of ill – halth and impending death associated with the epidemic in Nigeria, this study assesses the impact of HIV / AIDS on the socio – economic status. Specifically, it examines the effects of the epidemic on the level of imcome, level of productivity, marital ...

  4. HIV/AIDS in Oyo State, Nigeria: Analysis of Spatial Pattern of ...

    African Journals Online (AJOL)

    DrNneka

    recognized in 1981 in New York, a number of factors, habits and practices have .... poses as a stimulus which catalyzes the manifestation of the symptoms of. AIDS as ... the study on the geographical or spatial distribution of HIV/AIDS cases in.

  5. The Impact of Credit on Poultry Farm Productivity in Oyo State, Nigeria

    African Journals Online (AJOL)

    Results show that informal sources of credit are still preferred and more than half of the respondents are credit constrained. The statistically significant factors that affect farm productivity include value of feed, quantity of water, numbers and age of birds, training and the credit constraint condition of farmers. Credit constraint ...

  6. A Study among Bereaved Persons in Oyo and Oke-Ogun Areas

    African Journals Online (AJOL)

    User

    Mobile Phone: +2348034670349. Abstract ... relationships which will help them to cope successfully with bereavement crisis and recover quickly ... The study established that social support had a significant impact on symptoms of ... One of such support is social support which has been defined as interpersonal interactions ...

  7. Risk communication. Risk studies in social science; Risk communication. Risk kenkyu eno shakai kagakuteki approach

    Energy Technology Data Exchange (ETDEWEB)

    Asami, M. [Keio Univ., Tokyo (Japan)

    1995-11-05

    It is recently, that is, in and after the 1980s that socio-scientific approaches began to be made to studies on `risk`. It started to be made clear that the progress of the scientific technology does not necessarily bring about good news to man, and obvious estrangement has begun to appear between scientific evaluation and social evaluation of risk. The subject of risk communication (RC) study is to tackle a proposition whether the estrangement will continue to exist as estrangement or the estrangement can be made smaller by any means. This paper explains the recent trend of the study. For example, as for how each individual thinks about risk, that is, the risk perception, a new framework is trially being constructed by introduction of the quantitative method using psychometrics. A duty of RC is to serve to bridge the gap between scientific technology and society which are controlled by values which are incompatible with each other. Therefore, RC will be more and more important. 15 refs., 1 fig., 2 tabs.

  8. Application of wavelet transform to seismic data; Wavelet henkan no jishin tansa eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Nakagami, K; Murayama, R; Matsuoka, T [Japan National Oil Corp., Tokyo (Japan)

    1996-05-01

    Introduced herein is the use of the wavelet transform in the field of seismic exploration. Among applications so far made, there are signal filtering, break point detection, data compression, and the solution of finite differential equations in the wavelet domain. In the field of data compression in particular, some examples of practical application have been introduced already. In seismic exploration, it is expected that the wavelet transform will separate signals and noises in data in a way different from the Fourier transform. The continuous wavelet transform displays time change in frequency easy to read, but is not suitable for the analysis and processing large quantities of data. On the other hand, the discrete wavelet transform, being an orthogonal transform, can handle large quantities of data. As compared with the conventional Fourier transform that handles only the frequency domain, the wavelet transform handles the time domain as well as the frequency domain, and therefore is more convenient in handling unsteady signals. 9 ref., 8 figs.

  9. Spatial autocorrelation method using AR model; Kukan jiko sokanho eno AR model no tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Yamamoto, H; Obuchi, T; Saito, T [Iwate University, Iwate (Japan). Faculty of Engineering

    1996-05-01

    Examination was made about the applicability of the AR model to the spatial autocorrelation (SAC) method, which analyzes the surface wave phase velocity in a microtremor, for the estimation of the underground structure. In this examination, microtremor data recorded in Morioka City, Iwate Prefecture, was used. In the SAC method, a spatial autocorrelation function with the frequency as a variable is determined from microtremor data observed by circular arrays. Then, the Bessel function is adapted to the spatial autocorrelation coefficient with the distance between seismographs as a variable for the determination of the phase velocity. The result of the AR model application in this study and the results of the conventional BPF and FFT method were compared. It was then found that the phase velocities obtained by the BPF and FFT methods were more dispersed than the same obtained by the AR model. The dispersion in the BPF method is attributed to the bandwidth used in the band-pass filter and, in the FFT method, to the impact of the bandwidth on the smoothing of the cross spectrum. 2 refs., 7 figs.

  10. Water supply method to the fuel cell cooling water system; Nenryo denchi reikyakusuikei eno kyusui hoho

    Energy Technology Data Exchange (ETDEWEB)

    Urata, T. [Tokyo (Japan); Nishida, S. [Tokyo (Japan)

    1996-12-17

    The conventional fuel cell has long cooling water piping ranging from the fuel cell exit to the steam separator; in addition, the supply water is cooler than the cooling water. When the amount of supply water increases, the temperature of the cooling water is lowered, and the pressure fluctuation in the steam separator becomes larger. This invention relates to the water supply method of opening the supply water valve and supplying water from the supply water system to the cooling water system in accordance with the signal of the level sensor of the steam separator, wherein opening and closing of the supply valve are repeated during water supply. According to the method the pressure drop in every water supply becomes negligibly small; therefore, the pressure fluctuation of the cooling water system can be made small. The interval of the supply water valve from opening to closing is preferably from 3 seconds to 2 minutes. The method is effective when equipment for recovering heat from the cooling water is installed in the downstream pipeline of the fuel cell. 2 figs.

  11. Adjustment of muscle function to flight in bats; Komori no kinkino no hiko eno tekio

    Energy Technology Data Exchange (ETDEWEB)

    Yamashita, M. [Institute of the Space and Astronautical Science,Tokyo (Japan); Choi, I.H.

    1999-12-05

    This paper outlines the muscle of bats that generates a motive force for flight. The weight of the muscle is less compared with that of birds. The energy required for flight is twice as much as that for running. Conversely, in view of metabolic cost (transporting cost) for moving a unit mass for a unit distance, the transporting cost of bats for flying is one fifth. The acquisition of this flight ability through evolution can be inferred from the fossils of reptiles. Bats, having a stream-lined body shape and a small body mass, are capable of efficient flight. A fast durable flight is possible by having the pectoral muscle constituted of speed muscles of oxidation/glycolysis muscle fiber, a well-developed oxygen transporting system, the arrangement around the capillary of mitochondria and fat grains that are cell organs for producing energy, and a high-density contact between the capillary and the muscle fiber. The muscle functions at low body temperature and imparts adaptability to hibernation with the body temperature lowered. The flight is controlled by the cycle and synchronized with this biological clock, optical cycle and change in temperature. (NEDO)

  12. Resting Tension Affects eNOS Activity in a Calcium-Dependent Way in Airways

    Directory of Open Access Journals (Sweden)

    Paschalis-Adam Molyvdas

    2007-03-01

    Full Text Available The alteration of resting tension (RT from 0.5 g to 2.5 g increased significantly airway smooth muscle contractions induced by acetylcholine (ACh in rabbit trachea. The decrease in extracellular calcium concentration [Ca2+]o from 2 mM to 0.2 mM reduced ACh-induced contractions only at 2.5 g RT with no effect at 0.5 g RT. The nonselective inhibitor of nitric oxide synthase (NOS, NG-nitro-L-arginine methyl ester (L-NAME increased ACh-induced contractions at 2.5 g RT. The inhibitor of inducible NOS, S-methylsothiourea or neuronal NOS, 7-nitroindazole had no effect. At 2.5 g RT, the reduction of [Ca2+]o from 2 mM to 0.2 mM abolished the effect of L-NAME on ACh-induced contractions. The NO precursor L-arginine or the tyrosine kinase inhibitors erbstatin A and genistein had no effect on ACh-induced contractions obtained at 2.5 g RT. Our results suggest that in airways, RT affects ACh-induced contractions by modulating the activity of epithelial NOS in a calcium-dependent, tyrosine-phosphorylation-independent way.

  13. Riik hakkab Via Baltica maanteed neljarealiseks joonistama / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2008-01-01

    Ilmunud ka: Postimees : na russkom jazõke 25. sept. lk. 2. Pärnu maavalitsuse ja maanteeameti eestvedamisel alustatakse Tallinnast Iklani kulgeva Via Baltica liiklussoone teemaplaneeringut, mille järgi tuleb Pärnumaal leida lahendused Are ja Pärnu ümbersõidule ning Nurme õgvendusele. Arvamust avaldab Are vallavanem Jaanus Männik

  14. REŠEVANJE DELOVNIH SPOROV S SODIŠČU PRIDRUŽENO MEDIACIJO

    OpenAIRE

    Goričan Podbrežnik, Sabina

    2016-01-01

    Za človeško družbo je značilno, da se v njej pojavljajo spori.Enega izmed načinov reševanja sporov predstavlja mediacija kot glavni in tipični predstavnik alternativnega reševanja sporov. S sprejetjem Zakona o mediaciji v civilnih in gospodarskih zadevah se je Slovenija pridružila državam, ki imajo zakonsko urejeno mediacijo. Na podlagi Zakona o alternativnem reševanju sodnih sporov pa je mediacija postala tudi del rednega poslovanja slovenskih sodišč. Sodišču pridružena mediacija je edini po...

  15. Model Skinner Operant Conditioning automata i bionički naučeno upravljanje robota

    OpenAIRE

    Cai, Jianxian; Hong, Li; Cheng, Lina; Yu, Ruihong

    2016-01-01

    Fuzzy Skinner Operant Conditioning Automaton (FSOCA) sastavljen je na temelju Operant Conditioning mehanizma primjenom teorije neizrazitih skupova. Osnovno obilježje automata FSOCA je sljedeće: neizraziti rezultati stanja pomoću Gausove funkcije koriste se kao skupovi neizrazitog stanja; neizrazita pravila preslikavanja (fuzzy mapping rules) kod fuzzy-conditioning-operacije zamjenjuju stohastičke "conditioning-operant" skupove preslikavanja. Stoga se automat FSOCA može koristiti za opisivanje...

  16. Pärnu võimukoalitsioon kutsub pataljoni toetama / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2006-01-01

    Pärnu võimuerakonnad kutsuvad linna ja maakonna elanikke kõnekoosolekule, kus nad soovivad avaldada nördimust kaitseministeeriumi plaani üle sulgeda selle aasta lõpul Pärnu üksik-jalaväepataljon

  17. Maavanema avaldus surus linnavõimu kaitsesse / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2008-01-01

    Pärnu maavanem Toomas Kivimägi kritiseeris linnavalitsust Via Baltica Pärnu ümbersõidu projekti venimise pärast. Linnapea Mart Viisitamm ei pea avaldust põhjendatuks. Vt. samas lk. 15: Mart Viisitamm. Demokraatia või diktatuur - selles on küsimus

  18. Pidupäevaüritused olid Eestile ilus kingitus / Andris Tammela, Eno-Gerrit Link

    Index Scriptorium Estoniae

    Tammela, Andris

    2008-01-01

    Ülevaade EV 90. aastapäeva juubeliüritusest Pärnus. Vt. samas: Vabariigi juubel värvis Pärnu sinimustvalgeks; Head emotsioonid Eesti aastapäevalt: Are vallavanem Jaanus Männik, Euroopa Parlamendi liige Marianne Mikko, Pärnu linnavolikogu liikmed Valter Parve ja Raul Sarandi ja Pärnu maavanem Toomas Kivimägi

  19. Abilinnapea tõrjub opositsiooni süüdistusi / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2008-01-01

    Pärnu linnavalitsuse rahanduse abilinnapea Vambo Talu ei nõustu IRL poliitikute süüdistustega, et linna viletsas finantsolukorras on süüdi volikogu loata eelmise aasta eelarvest kärbitud 116 miljonit krooni

  20. Streigi saatus selgub täna lõunaks / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2007-01-01

    Riiklik lepitaja Henn Pärn tegi viimase kompromissettepaneku. Juhul, kui ametiühingute, tööandjate ja lepitaja kohtumisel osalised seda heaks ei kiida, alustatakse hoiatusstreigiga. Vt. samas: Pärnu streikivate bussijuhtide pöördumine linnarahva poole

  1. Estonia juhti kahtlustatakse ettevõtte varade omastamises / Ester Vilgats, Eno-Gerrit Link, Teet Roosaar

    Index Scriptorium Estoniae

    Vilgats, Ester

    2008-01-01

    Endine Pärnu linnapea, taastusravikeskuse Estonia pikaaegne juht Vello Järvesalu peeti kinni kahtlustatuna ettevõtte varade omastamises suures ulatuses. Kommenteerivad: Mart Viisitamm, Jane Mets ja Ahti Kõo

  2. Päästjatele tuli mullu tuhat väljakutset / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2006-01-01

    Pärnumaa päästeteenistus sai 2005. a. kõige rohkem väljakutseid Pärnusse ning Via Baltica äärde jäävatesse Pärnumaa valdadesse ja Vändrasse. Kaart: Pärnumaa päästeteenistuste väljasõidud omavalitsustesse 2005

  3. Pärnu linnavalitsuse hinnang esimesele valitsemisaastale / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2006-01-01

    Ajaleht esitas Pärnu linnajuhtidele kolm küsimust. Vastasid linnapea Mart Viisitamm, abilinnapea majanduse valdkonnas Raul Sarandi, abilinnapea arengu ja planeerimise valdkonnas Mart Alliku, abilinnapea kultuuri, spordi ja sotsiaalvaldkonnas Margus Tammekivi ja linnavalitsuse liige turvalisuse valdkonnas Simmo Saar. Arvamust avaldavad Reformierakonna Pärnu piirkonna esimees Väino Hallik ja SDE esindaja Pärnu linnavolikogus Valter Parve

  4. Poliitikud ei leidnud staadioni planeeringule uusi lahendusi / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2008-01-01

    Riigikogu Pärnumaa saadikuteühenduse ja Pärnu linnavõimu esindajate ning spordiseltsi Kalev juhtide nõupidamine Kalevi staadioni ümberehituse käimalükkamiseks lõppes tulemusteta, sest kõiki osapooli rahuldava tulemuseni ei jõutud. Kommenteerivad Mark Soosaar ja Vello Järvesalu

  5. Sotsid said prostitutsiooni ürituse pärast noomida / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2006-01-01

    Ilmunud ka: Pärnu Postimees 16. märts lk. 3. Pärnu linnavalitsuse kultuuriosakonna peaspetsialist Tair Anton tegi kaubanduskeskuses Port Artur 2 prostitutsiooni vastu vastu allkirju kogunud sotsiaaldemokraatidele loata avaliku ürituse korraldamise eest suulise märkuse

  6. Koalitsioon ei plaani linna juhtimises muudatusi / Ester Vilgats, Eno-Gerrit Link

    Index Scriptorium Estoniae

    Vilgats, Ester

    2008-01-01

    Pärnu koalitsiooninõukogu sõnul pole põhjust linnapea Mart Viisitamme, abilinnapea Simmo Saare ja koalitsiooninõukogu esimehe Vello Järvesalu välja vahetamiseks, kuna kedagi pole süüdi mõistetud

  7. President tunnustab Pärnumaad kümne riikliku autasuga / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2007-01-01

    Pärnumaalt saavad iseseisvuspäeva puhul riikliku autasu kümme inimest. Vt. samas: Ester Vilgats. Ivar Kaldasaunal on alati kollektiiviga vedanud; Vello Lahtvee kolmkümmend aastat kohtunikuna. Teenetemärgi pälvinute seas on Lääne-Eesti päästekeskuse direktor Ivar Kaldasaun ja Pärnu maakohtu kohtunik Vello Lahtvee. Vt. ka juhtkiri lk. 15: Vilgats, Kalev. Ebaõigluse visa vastupanu. Rüütliristi kavaler Harald Nugiseks jäi taas teenetemärgist ilma

  8. Prospects to solar energy power generation in space. Uchu taiyo hatsuden eno tenbo

    Energy Technology Data Exchange (ETDEWEB)

    Kudo, I. (Electrotechnical Laboratory, Tsukuba (Japan))

    1993-05-01

    Solar energy power generation in space uses large arrays of solar cells developed on a geosynchronous orbit to obtain electric energy, which is transmitted to the earth using microwaves. The idea had already been advocated in 1968, which was followed a decade later by joint discussions done by NASA and DOE. The concept intended to take care of the U.S. power demand by using 60 power plant satellites, each having an output of 5 GW. This expanse of the scale, regarded reasonable even today, calls for the solar cell arrays in space spreading over an area of 10 km [times] 5 km if silicon solar cells with a conversion efficiency of 15% are used, and rectenna on the ground (a received wave converting facility) forming an ellipse of 10 km [times] 13 km (assuming a location at the north latitude of 36[degree]). Although there are a number of problems in the idea such as transportation means to lift construction materials into the space and effect of microwaves on the ionosphere and the ecosystems, the Agency of Industrial Science and Technology organized a 'committee for investigating and studying the space power generation systems' in the fiscal year 1991, and has been moving discussions forward since then. 7 refs., 5 figs.

  9. Effect of water pollution on marine organisms; Sekiyu osen no kaiyo seibutsu eno eikyo hyoka

    Energy Technology Data Exchange (ETDEWEB)

    Ogata, M. [Okayama Univ., Okayama (Japan); Fujisawa, K. [Okayama Prefectural Fisheries Experiment Station, Okayama (Japan)

    1997-10-10

    Toxicity of petroleum component to aquatic organisms appears as a result of its deposition onto living organisms followed by its migration into bodies of the organisms, and emergence of toxicity from the migrated component. Effect evaluation processes standing on this viewpoint may include the exposure monitoring or migration monitoring, in which the petroleum component migrated into marine organisms is analyzed and the state of the component concentrated in these organisms is measured, or effect monitoring, in which actions of the petroleum component in the organisms are investigated. The effects of petroleum on aquatic organisms would include the following occurrence: direct fatal toxicity acting on cells and membranes, quasi-fatal toxicity causing death indirectly through feeding actions and abnormal actions, direct coating of oil on surface of organisms, which prevents movability and feeding actions of the organisms and reduces hydrophilicity of plumes and hairs, pollution of living organisms due to migration of carcinogenic aromatic compounds into bodies of the living organisms, and change in species compositions and geographic distribution of living organisms due to change in physico-chemical environment. This paper explains cases of detection and identification of organic sulfur compounds, aromatic compounds, polycyclic aromatic compounds, paraffins, olefins and heavy metals in parametric compounds of petroleum. 20 refs., 4 figs., 3 tabs.

  10. Truncus Arteriosus in a 43 year old Male: Case Report | Ng'eno ...

    African Journals Online (AJOL)

    In truncus arteriosus, the embryologic truncus fails to properly divide in-utero resulting in the pulmonary, aortic and coronary arteries arising from a single ascending portion of this trunk. This condition is usually fatal within the first year of life without correction. Over the past two decades, there has been a dramatic expansion ...

  11. Trial to active seismic while drilling; Jinko shingen wo mochiita SWD eno kokoromi

    Energy Technology Data Exchange (ETDEWEB)

    Tsuru, T; Kozawa, T [Japan National Oil Corp., Tokyo (Japan). Technology Research Center

    1996-10-01

    This paper describes the development of a more stable SWD system with larger energy by adding an artificial seismic source near the bit. SWD is a technique by which the seismic wave generated while drilling of rocks by bit can be observed on the ground surface and the records equivalent to the reverse VSP can be obtained. For this system, a shell with a vibrator was fixed immediately on the bit as a sub-generator, and total energy of usual impact by the bit and vibration by the vibrator was used as a seismic source for SWD. For the seismic wave generation mechanism of this vibrator, the shell was resonated by the magnetostrictive element, and vibration was given to the bit and drilling pipe. When this seismic source is used, only single frequency is obtained for each vibration due to the utilization of resonance of shell. Therefore, the generation patterns should be made, by which wide band energy can be obtained after the interaction. Since the survey was conducted using this bottom hole seismic source at the drilling depth more than 3,000 m, it was necessary to enhance the vibration energy. 2 refs., 2 figs.

  12. Application of EM tomography to detect a buried pipe; EM tomography no maisetsukan tansa eno tekiyorei

    Energy Technology Data Exchange (ETDEWEB)

    Sakashita, S [OYO Corp., Tokyo (Japan)

    1996-10-01

    EM tomography was applied to detect buried pipes. Underground radar exploration method is limited to 10m in depth. Positive use of bored holes is desirable, and in such case, magnetic logging based on the magnetic susceptibility (MS) contrast between buried body and surrounding ground is effective. The primary magnetic field is generated by coil current, and the secondary one is generated by the primary one responding to foreign bodies in the ground. Since the measured primary magnetic field of low frequency within 10Hz can be treated as static magnetic field responding to MS in the ground, it is useful to determine MS distributions. Since the measured magnetic field of high frequency within 100kHz can be treated as induction field responding to conductivity in the ground, it is useful to determine resistivity distributions. The EM tomography which can image both above distributions by using electromagnetic wave in a wide frequency range, was applied to detect buried pipes. The EM tomography could detect an buried foreign body of 3m in diameter at 10m in distance between bored holes. The theoretical equation for analysis was also derived. 5 refs., 9 figs., 1 tab.

  13. Application of wear resistant spraying for diesel engine; Diesel kikan eno taimamo yosha no tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Kitajima, Y. [Mitsui Engineering and Shipbuliding Co. Ltd., Tokyo (Japan)

    1999-03-31

    Diesel engines used widely as propelling engines of ships have increasingly been provided with a high output and a high thermal efficiency; their structural members, particularly, the component parts for combustion chambers are therefore used under severe conditions, giving rise to the need of surface treatment and surface reforming of the members. Parts for marine diesel engines are huge, so that the technology applicable to the surface treatment and reforming are limited in point of facility and cost; therefore, most suitable is thermal spraying. This paper primarily discusses, among marine diesel engines, a 2-cycle low-speed engine with a 260-980mm bore used for the main engine of a merchant ship such as a container ship, bulk carrier or a tanker, and a 4-cycle medium-speed engine with a 300-420mm bore used for the main engine of a naval vessel; the paper explains the application status of a thermal spraying technology which is in progress to cope with the high output and high thermal efficiency of the diesel engines, explaining particularly the story of the development and the technological features of the wear resistant thermal spraying, which has been put to practical use, on the cylinder liner and the piston ring of the 4-cycle medium-speed engine. (NEDO)

  14. Application of ECS to a hybrid automobile; `ECS` no hybrid jidosha eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Shimizu, M.; Okamura, T.

    1997-01-30

    This paper describes a simulation for a case when an energy capacitor system (ECS) is mounted in a hybrid electric vehicle in place of secondary batteries. The ECS is electric power storage equipment consisted of capacitors and electronic circuits, and capable of quick charge and discharge at high efficiency. Its energy density per unit weight is about the same as lead-acid batteries, but its output density is greater than any type of batteries. Being free of deterioration due to charge and discharge, its cycle life is almost limitless. In order to suppress heat generation, a switching converter is used to control the output to about 300W. However, internal resistance of an ECS is smaller than in an equivalent secondary battery, and internal loss and heat generation stay as low as 1/5 to 1/10. Discussions have been given on cases of using the ECS in small passenger cars, small buses/trucks, and large buses. Since the ECS can use the stored power to about 94% of the capacity, and its cycle life is sufficiently long, it can operate with charge capacity as small as 1/4 of a lead-acid battery. The weight can also be reduced largely. Regenerative power storage efficiency is high, fuel consumption can be improved, heat generation is less, and no forced cooling is required. 9 refs., 4 figs., 1 tab.

  15. Influence of life line stoppage on building equipments; Lifeline tozetsu no kenchiku setsubi eno eikyo

    Energy Technology Data Exchange (ETDEWEB)

    Sadohara, S. [Yokohama National University, Yokohama (Japan). Faculty of Engineering

    1995-06-05

    Our daily life is being supported by electricity in various ways. This paper, explains the influence of the stoppage of the electricity, affecting infrastructures, buildings and people`s daily life based on the survey result of a long term electricity stoppage in Hiroshima City in September 1991. This paper also introduces the survey result of emergency generators operation in Japan and in the U.S. Last, the ways and ideas to make lifeline reliability higher in the future are summarized. 1 ref., 11 figs., 7 tabs.

  16. PV glass curtain walls; Kenzai ittaigata taiyo denchi gaiheki no kaihatsu (glass curtain wall eno tekiyo)

    Energy Technology Data Exchange (ETDEWEB)

    Yoshida, T.; Iwai, T.; Ouchi, T.; Ito, T.; Nagai, T.; Shu, I. [Kajima Corp., Tokyo (Japan); Arai, T. [Showa Shell Sekiyu K.K., Tokyo (Japan); Ishikawa, N.; Tazawa, K.

    1997-12-20

    Reported in this article are PV (photovoltaic) modules now under development for integration into building walls. First of all, the power generating capability of PV modules and appropriate use of the generated power are studied, and the performance (resistance to fire or incombustibility, strength and durability, appearance and design, and dimensional standardization) that such outer wall materials are to be equipped with are determined. Next, module development, installation technique, computer graphics-aided facade designing, and real size module-using proof test are studied before installability, the power to be generated, and designs are finalized. In the development of modules, design evaluation involves the combining of various kinds of glass, solar cells, back sheets, and fillers, and the importance is confirmed of the prevention of insulation degradation around the modules. As for the methods of installation, the gasket method and aluminum sash method, etc., are tested. In the study of facade design, it is found that various expressions are possible by properly choosing gasket colors, module types, and kinds of glass to cover the openings. 1 ref., 6 figs., 3 tabs.

  17. Waste minimization activities in Toyota Motor Corporation; Haikibutsu teigen eno torikumi jokyo

    Energy Technology Data Exchange (ETDEWEB)

    Taguchi, S.; Yamamoto, N.; Kurai, H. [Toyota Motor Corp., Aichi (Japan)

    1998-07-01

    Toyota`s waste reduction efforts based on a drive for dealing with the source of waste generation are introduced. For the propulsion of the policy for dealing directly with the origin of waste, it is necessary to convert the existing manufacturing processes that give high priority to product quality and low production cost into environmental impact reduction oriented processes. In particular, conversion of materials into those that are easier to recycle, technology for reducing defective products, technology for the completion of recycling within the process involved, and the simplification of all the processes are mentioned. For the cleaning job in the machining process, a detergent enhanced in oil/water separating capability is developed, and this prolongs doubly the detergent replacement period and decreases the waste liquid to a 1/4 or less of what the conventional method produces. For the handling of foundry sand that is yielded in great quantities, a flow classification system is developed to replace the conventional gravitational classifier, and the reusable coarse-grain sand in the collected dust which occupies approximately 70% of the whole waste is now recovered for reuse. In the vehicle body coating process, a newly-developed robot arm type coating system is developed, which halves the coating waste. 2 refs., 9 figs., 1 tab.

  18. Role of biotechnology in future agriculture. Korekarano nogyo to biotechnology eno kitai

    Energy Technology Data Exchange (ETDEWEB)

    Komano, T. (Kyoto Univ., Kyoto (Japan). Faculty of Agriculture)

    1992-09-01

    In comparison with ancient times when everything is handled empirically, biological matter suitable for purposes can be produced and utilized faster and more reliably these days when life science has made a great advance. The advancement is related to new breeding technology and production means, and those means offer the point of contact between biotechnology and agriculture. The application fields of biotechnology are microbiology, cell technology, enzyme technology (bioreactor), and gene engineering. High yield, high content of high value ingredients as foods, adaptability to environment, resistance to disease and insect damage, etc. may be the subjects expected for future agricultural organisms. There may be many areas where biotechnology is related to those organisms, but a discussion is made in this report centering around the problem in breeding. Outlines are given on the applied cases of cell technological method, gene engineering method, and recombinant DNA technology, as well as on gene engineering for plants and animals. 10 refs., 7 figs.

  19. Astronaut suitability requirements and selection process; Uchu hikoshi tanjo eno michi (shishitsu yokyu)

    Energy Technology Data Exchange (ETDEWEB)

    Miyoshi, H. [National Space Development Agency of Japan, Tokyo (Japan)

    1999-10-05

    Manned space activities at National Space Development Agency of Japan and the suitability requirements that an astronaut is supposed to satisfy are described. At the first phase, candidates have to participate in a manned space experiment utilizing a NASA space shuttle and, in 1985, Mori, Mukai, and Doi were selected to be payload specialists. At the second phase, Astronauts Wakata, Doi, and Mori were sent to the mission specialist training course, this being one of the jobs aboard a space shuttle, which was for preparing for the construction and operation of the international space station. In January, 1996, Astronaut Wakata performed extravehicular tool manipulation and so forth, and Astronaut Doi did the same in 1997. The endowments that an astronaut is expected to have include undoubted professionalism, adaptability to branches out of his field, adaptability to a prolonged stay in space, spirit of teamwork and coordination, and ability to perform wide range of duties aboard an international space station. (NEDO)

  20. Projekteerijad asuvad kesklinna võimla kavandit täiendama / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2001-01-01

    Pärnu Vanalinna põhikooli kõrvale kavandatavast võimlast. Võimla eskiisprojektide konkursi võitis (2. koht.) Ott Kadariku ja Mihkel Tüüri töö "Jae-Ja", 3. koha sai Kalle Kadalipu töö "Neo"

  1. Application of essential facility doctrine to transmission grid; Sodenmo eno essential facility no hori no tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Maruyama, M. [Central Research Institute of Electric Power Industry, Tokyo (Japan)

    1997-06-01

    This paper arranges the essential facility doctrine in America and describes it according to each judgment example how the doctrine is applied on the access of electricity supply companies to transmission grids. By applying the result to the situation of Japan, the point at issue occurring in the range of the Anti-Monopoly Law was arranged and investigated when third parties (power generating manufacturers) access the transmission grids of electricity supply companies in the form of wholesale or self transmission in the electricity supply industry of Japan. In the judgment example of America, a transmission grid can be considered as essential facility. The refusal of essential facility application is judged to be illegal only when it aims at keeping and expanding the leading market share without a fair reason. The application of essential facility can be refused when the transmission line is insufficient in capacity, when no necessary technical conditions are satisfied during use, or when the cost generated during use cannot be collected. 18 refs., 7 figs., 2 tabs.

  2. Application of ceramics to the sliding seat of valve bridge; Valve bridge yodobu eno ceramics tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Matsui, T; Ono, T [Mitsubishi Motors Corp., Tokyo (Japan)

    1997-10-01

    For use in the valve train, using an OHV (over head valve) configuration. of a 4 valve diesel engine for trucks and buses; we developed a valve bridge, a component of a valve train, with a ceramic head that is made of silicon nitride(Si3N4) in contact with a rocker arm in order to reduce cost and improve wear resistance for further diesel engine emissions regulations. In order to evaluate the effect of this valve bridge, RIG tests and durability tests on actual engines were carried out. 7 figs., 2 tabs.

  3. effect of dl-carnitine on tissue content of ad eno ine triphospha te

    African Journals Online (AJOL)

    BSN

    values of 16.2 ± 5.2µ mols lg dry weight for ATP and I 1.7± 2.5 ~11nols/g dry weight for CP in normal (non ischaem1c) myocardial tissue. Continuous perfusion of the heans "ith perfusate contaming 4.9µmols/ml. DL-Carnitine appeared to prevent the lowermg of ATP and CP levels as a result of induction of ischaemia.

  4. Utilization of new materials in prestressed concrete. Shin zairyo no puresutoresuto concrete eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Imai, Y. (Taisei Corp., Tokyo (Japan)); Kato, H. (Building Research Inst., Tokyo (Japan)); Mutsuyoshi, H. (Saitama Univ., Urawa (Japan). Faculty of Engineering)

    1994-03-31

    In this session for the new materials, almost all of them were the presentation on the fiber reinforced plastics (FRP). Based on these facts, the topics of new materials about PC centered around FRP, and consequently it was found that how it was expected as the new materials and how it is being watched with keen interest. Even in FRP, the presentations on the carbon fiber reinforced plastics (CFRP) and aramid fiber reinforced plastics (AFRP) were a little bit more than those on the glass fiber reinforced plastics (GFRP), and therefore they were felt to be predominant. Although the ones about a fundamental study on the material characters of FRP held approximately 70%, as a content, there were 6 presentations on the design and execution of the actual bridges in which FRP was used for the PC take-up materials and the oblique cable of cable-stayed bridges, consequently it was found that FRP did not stay at a study stage, and was already shifting to the actual application stage. However, at the current situation, there were many of experimental ones like the small scale bridges in the golf courses, and furthermore it can not be said that a guideline for the design and execution is sufficiently established. 2 figs.

  5. Relation between front suspension layout and handling performance. Analysis depending on the Taguchi method and ADAMS; Front suspension layout to soda tokusei no kankei ni tsuite. Kiko kaiseki gengo wo mochiita hinshitsu kogaku ni yoru kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Okada, K [Daihatsu Motor Co. Ltd., Osaka (Japan)

    1997-10-01

    A variation of suspension layout gives an influence to the vehicle dynamics. Examined the suspension layout variation to make the handling performance change small. Analyzed the effect of suspension layout variation about steering response delay and gain besides the tire wear effect and movable load. 3 refs., 12 figs., 4 tabs.

  6. Fault analysis in the very shallow seismic reflection method; Gokusenso jishin hanshaho ni okeru danso kaiseki. 1

    Energy Technology Data Exchange (ETDEWEB)

    Nagumo, S; Muraoka, S; Kaida, Y; Takahashi, T [OYO Corp., Tokyo (Japan)

    1996-10-01

    To effectively use the very shallow seismic reflection for active fault survey, a method has been investigated by which fault structures can be appropriately reconstructed from the fault information detected in the original records. The first step of reconstructing the fault system from the travel time reflection curve was to grasp an outline of fault structure from the patterns of travel time curve observed in the original record. For the very shallow seismic reflection method, especially, the low velocity layers in a shallow part succeeding from the ground surface made the issue complicated. Then, the travel time reflection curves were calculated in the case of existing several horizontal reflection surfaces in the surface layer. The constant values, mean velocities to the depth at individual reflection surfaces were used for the approximation of velocities. The outline of fault structure was grasped from the observation of original record. Then, the structure was reconstructed from the travel time curves. When the mean velocity in the medium was known, reconstruction of the feature of reflection surfaces from the travel time curves could be determined by simple mapping. When the mean velocity was unknown, it was calculated using the reciprocal travel time from the common reflection surface for individual reflection surfaces. 7 figs.

  7. Wavefield analysis in inhomogeneous media by wavelet transform; Wavelet henkan ni yoru fukinshitsu baitai no hadoba kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Matsushima, J; Rokugawa, S; Kato, Y [The University of Tokyo, Tokyo (Japan). Faculty of Engineering; Yokota, T; Miyazaki, T [Geological Survey of Japan, Tsukuba (Japan); Ichie, Y [The University of Tokyo, Tokyo (Japan)

    1996-10-01

    Data processing techniques have been investigated for clarifying structures and physical properties of geothermal reservoirs in the deep underground by seismic exploration using multiple wells. They include the initial motion time-distance tomography, amplitude tomography, diffracted wave tomography, and structure imaging using reflected wave or scattered wave. When applying these data processing methods to observed records, weak and minor signals essentially required are canceled due to averaging the analytical fields. In this study, influence of inhomogeneous media on the wavefield was evaluated. Data were analyzed considering frequency by using wavelet transform by which time-frequency can be easily analyzed. From the time-frequency analysis using wavelet transform, it was illustrated that high frequency scattered waves, generated by scatterer like cracks or by irregularity on the reflection surface, arrive behind direct P-wave and direct S-wave. 5 refs., 8 figs.

  8. Causality analysis of alpha activities by multidimensional directed coherence; Tajigen yuko coherence ni yoru {alpha}ritsudo no ingasei kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Sakata, O.; Shimada, N.; Shiina, T. [University of Tsukuba, Tsukuba (Japan); Saito, Y.; Imanishi, N.

    1998-07-01

    Alpha activities as a basic component of EEG (electroencephalogram) are mainly observed with eye-closed and reported state, and indicates rhythmic and diffused pattern on the scalp. Therefore analysis of the relation among many sequences of alpha activities measured at different positions on the scalp is expected to be useful not only for diagnosing psychiatric but also for investigating mechanism of brain information processing by means of causality analysis that is, macroscopic estimation of flow pattern within brain. Although coherence analysis has been proposed as a method for estimating the direction and magnitude of information flow between two sequences, superposition of results for each pair of sequences can not represent true relation among the whole sequences. In this paper, we proposed the multidimensional directed coherence analysis by modifying two-channel formula in order to apply it to the analysis of multi-channel sequence of alpha activities. Results of simulation revealed that multidimensional directed coherence can indicate more quantitatively the relation among the multi-channel sequences compared with conventional two-channel formula. Moreover, the proposed method was applied to the analysis of EEG data of normal volunteer and patient. Results show the method can provide a useful diagnostic information by assessment of the signal flow pattern within brain. 16 refs., 10 figs.

  9. Theoretical analysis of film condensation in horizontal microfin tubes; Microfin tsuki suihei kannai gyoshuku no riron kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Honda, H; Wang, H [Kyushu University, Fukuoka (Japan). Institute of Advanced Material Study; Nozu, S [Okamaya Prefectural University, Okayama (Japan). Faculty of Computer Science and System Engineering

    2000-10-25

    A theoretical study has been made of film condensation in helically-grooved, horizontal microfin tubes. The annular flow regime and the stratified flow regime were considered. For the annular flow regime, a previously developed theoretical model was applied. For the stratified flow regime, the height of stratified condensate was estimated by a modified Taitel and Dukler model. For the upper part of the tube exposed to the vapor flow, numerical calculation of Laminar film condensation considering the combined effects of gravity and surface tension forces was conducted. The heat transfer coefficient at the lower part of the tube was estimated by an empirical equation for the internally finned tubes developed by Carnavos. The theoretical predictions of the circumferential average heat transfer coefficient by the two theoretical models were compared with available experimental data for four refrigerants and four tubes. Generally, the annular flow model gave a higher heat transfer coefficient than the stratified flow model in the high quality region, whereas the stratified flow model gave a higher heat transfer coefficient in the low quality region. For tubes with fin heights of 0.16 {approx} 0.24 mm, most of the experimental data agreed within {+-} 20% with the higher of the two theoretical predictions. (author)

  10. Function of mammalian genes regulation cellular growth; Saibo zoshoku wo seigyosuru dobutsu saibo idenshi no kino kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Matsumoto, K. [Nagoya University, Nagoya (Japan)

    1995-12-15

    Intracellular signaling from receptor tyrosine kindles in mammalian cells results in activation of a signal cascade that includes the guanine nucleotide binding protein Ras and the protein kinases Raf, MEK [Mitogen activated protein kindle (MAPK) or Extracellular signal regulated kinase (ERK) kinase] and MAPK. MAPK activation that is dependent on the coupling of Ras and Raf was reconstituted in yeast. Yeast genes were isolated that, when overexpressed, enhanced the function of Raf. One of them is identical to BMH 1, which encodes a protein similar to members of the mammalian 14-3-3 family. Bacterially synthesized mammalian 14-3-3 protein stimulated the activity of Raf prepared from yeast cells expressing c-Raf-1. Thus, the 14-3-3 protein may participate in or be required for activation of Raf. 9 refs., 2 figs.

  11. Three dimensional reflection velocity analysis based on velocity model scan; Model scan ni yoru sanjigen hanshaha sokudo kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Minegishi, M; Tsuru, T [Japan National Oil Corp., Tokyo (Japan); Matsuoka, T [Japan Petroleum Exploration Corp., Tokyo (Japan)

    1996-05-01

    Introduced herein is a reflection wave velocity analysis method using model scanning as a method for velocity estimation across a section, the estimation being useful in the construction of a velocity structure model in seismic exploration. In this method, a stripping type analysis is carried out, wherein optimum structure parameters are determined for reflection waves one after the other beginning with those from shallower parts. During this process, the velocity structures previously determined for the shallower parts are fixed and only the lowest of the layers undergoing analysis at the time is subjected to model scanning. To consider the bending of ray paths at each velocity boundaries involving shallower parts, the ray path tracing method is utilized for the calculation of the reflection travel time curve for the reflection surface being analyzed. Out of the reflection wave travel time curves calculated using various velocity structure models, one that suits best the actual reflection travel time is detected. The degree of matching between the calculated result and actual result is measured by use of data semblance in a time window provided centering about the calculated reflective wave travel time. The structure parameter is estimated on the basis of conditions for the maximum semblance. 1 ref., 4 figs.

  12. Inversion interpretation of the mise-a-la-masse data; Denryu den`i ho data no inversion kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Okuno, M; Hatanaka, H; Mizunaga, H; Ushijima, K [Kyushu University, Fukuoka (Japan). Faculty of Engineering

    1996-05-01

    A program was developed for the inversion interpretation of the mise-a-la-masse data, and was applied to a numerical model experiment and to the study of data obtained by actual probing. For the development of this program, a program was used that calculated by finite difference approximation the potential produced by a linear current source, and studies were made through forward interpretation, inversion interpretation of the acquired apparent resistivity data, comparison with the true solution, accuracy and tendency, and the limitations. In the simulation of a horizontal 2-layer model, the parametric value after 20 repetitions converged with deviation of 1% or lower. This program was applied to the data from probing the Hatchobara district, Oita Prefecture, using a model wherein the target area was divided into 5 from east to west, and into 2 in the direction of depth. The result suggested that there was a large-scale low-resistivity body deep in the ground in the southeastern part of the investigated area. Furthermore, there was a spot detected in the direction of east-northeast that suggested an electric structure continuous in the direction of depth and a fault-like structure discontinuous in the transverse direction. 7 refs., 9 figs.

  13. Interferometric SAR and land deformation. Analysis using the dislocation model; Interferometric SAR to chikaku hendo. Dislocation model wo mochiita kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Matsushima, J; Otaki, T; Tanaka, A; Miyazaki, Y [Geological Survey of Japan, Tsukuba (Japan)

    1996-05-01

    The diastrophism by the earthquake-induced dislocation is investigated by interferometry (INSAR) which represents the diastrophism by the interference fringes of equiphase difference lines. A joint research group at Geographical Survey Institute and National Space Development Agency showed the diastrophism in the vicinity of the ground surfaces before and after the Hyogoken Nanbu Earthquake by the INSAR interference images in 1995. This paper discusses the effects of observation in the vision line direction from the satellite and dislocation parameters on the interference images. The dislocation model uses a slanted rectangular model in a semi-infinite medium, to calculate static displacements and strain distributions at the ground surface, when dislocation changes. It is found that the INSAR interference images, detecting displacements in the vision line direction from the satellite, significantly change as the vision line direction changes, and that the actual displacement cannot be given by the images alone. This paper also shows sensitivity of the interference images to the dislocation parameters. 3 refs., 9 figs., 1 tab.

  14. Magnetic constraints of basement structure offshore of western Kyushu, Japan; Kyushu seiho kaiiki ni okeru jiki ijo no kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Okuma, S; Nakatsuka, T [Geological Survey of Japan, Tsukuba (Japan); Ishihara, T [Japan National Oil Corp., Tokyo (Japan)

    1996-05-01

    This paper describes the results from the qualitative analysis of magnetic anomalies offshore of western Kyushu and from an analysis by a three-dimensional two-layer model inversion. The analysis ranged from Kyushu on the east to Jeju Island on the west and from the southern part of the Korean Peninsula on the north to Tanegashima and Yakushima Islands on the south, namely, the area of 580km from east to west and 580km from south to north. The analytical data used was Magnetic Anomaly Map of Asia (GSJ and CCOP, 1994). In the qualitative analysis, a pseudogravity anomaly map and a pole gravity anomaly map were prepared from the total magnetic force anomaly map by means of a frequency filter operation. As a result, it was noted that two distinctive magnetic high belts existed in the margin of the Tunghai Shelf, extending from the sea area to the west of the Nansei Islands continuously to NNE, and being distributed transversely through the Goto sedimentary basin. Additionally, in the inversion analysis, it was demonstrated that the magnetic basement became shallow at the margin of the Tunghai Shelf north of latitude 31 degrees north, extending nearly in the NNE direction through west of the Goto Islands, west of Tsushima Island, and continuing to the southern coast of the Korean Peninsula. 6 refs., 4 figs.

  15. Preliminaries on core image analysis using fault drilling samples; Core image kaiseki kotohajime (danso kussaku core kaisekirei)

    Energy Technology Data Exchange (ETDEWEB)

    Miyazaki, T; Ito, H [Geological Survey of Japan, Tsukuba (Japan)

    1996-05-01

    This paper introduces examples of image data analysis on fault drilling samples. The paper describes the following matters: core samples used in the analysis are those obtained from wells drilled piercing the Nojima fault which has moved in the Hygoken-Nanbu Earthquake; the CORESCAN system made by DMT Corporation, Germany, used in acquiring the image data consists of a CCD camera, a light source and core rotation mechanism, and a personal computer, its resolution being about 5 pixels/mm in both axial and circumferential directions, and 24-bit full color; with respect to the opening fractures in core samples collected by using a constant azimuth coring, it was possible to derive values of the opening width, inclination angle, and travel from the image data by using a commercially available software for the personal computer; and comparison of this core image with the BHTV record and the hydrophone VSP record (travel and inclination obtained from the BHTV record agree well with those obtained from the core image). 4 refs., 4 figs.

  16. MT2-D inversion analysis in Kakkonda geothermal field; Kakkonda chinetsu chiiki ni okeru MT ho nijigen kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Yamane, K; Takasugi, S [Geothermal Energy Research and Development Co. Ltd., Tokyo (Japan); Miyazaki, S [Japan Metals and Chemicals Co. Ltd., Tokyo (Japan); Uchida, T [New Energy and Industrial Technology Development Organization, Tokyo, (Japan)

    1996-05-01

    Data, collected from an MT method-assisted survey conducted in the Kakkonda geothermal region in 1987, was re-examined, and a new structure was found. The review was carried out by use of a 2D analysis in the TM mode. According to the 1D analysis of 1987 and the geological data gathered then, it is estimated that the resistivity structure of this region runs in the northwest-southeast direction. A northeast-southwest traverse line was set for this analysis, orthogonal to the strike, and the impedance at each observation spot was caused to rotate to this direction across the whole range of frequency. Furthermore, in 1994-95, surveys were conducted using arrayed CSMT/MT methods. All these sum up to indicate that a high-resistivity region extends northwest in the southwestern part of the Kakkonda river but that there exists a low-resistivity region of several 10 Ohm m centering about the B traverse line. The high-resistivity region deep in the ground being the target of excavation in the Kakkonda region, to collect knowledge about this high-resistivity is important, and here the effectiveness of the 2d analysis has been verified. 5 refs., 11 figs.

  17. Improvement of two-dimensional gravity analysis by using logarithmic functions; Taisu kansu wo mochiita nijigen juryoku kaiseki no kairyo

    Energy Technology Data Exchange (ETDEWEB)

    Makino, M; Murata, Y [Geological Survey of Japan, Tsukuba (Japan)

    1996-05-01

    An examination was made, in the two dimensional tectonic analysis by gravity exploration, on a method that was applicable from a deep underground part to a shallow geological structure by using logarithmic functions. In the examination, a case was considered in which an underground structure was divided into a basement and a covering formation and in which the boundary part had undulations. An equation to calculate a basement structure from a gravity anomaly was derived so that, taking into consideration the effect from the height of an observation point, it might be applicable to the shallow distribution of the basement depth. In the test calculation, a model was assumed reaching the depth near the surface with the basement being a step structure. Density difference was set as 0.4g/cm{sup 3}. An analysis using an equation two-dimensionally modified from Ogihara`s (1987) method produced a fairly reasonable result, showing, however, a deformed basement around the boundary of the step structure, with the appearance of a small pulse-shaped structure. The analysis using logarithmic functions revealed that the original basement structure was faithfully restored. 3 refs., 5 figs.

  18. Structural study of synthetic polymers by MALDI-TOFMS; MALDI-TOFMS ni yoru gosei kobunshi no kozo kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Noguchi, K.; Hirayama, K. [Ajinomoto Co. Inc., Tokyo (Japan)

    1998-08-01

    As observation results on the time-dependent change in the ring-opening reaction of novolac epoxy resin with acetic acid by MALDI-TOFMS, the epoxy ring was opened with reaction time, the hydroxy group formed by the ring-opening reaction was acetylated, those components were measured. In the case of the FABMS/MS observation of materials and the reaction products, the estimation structure could be confirmed from the measured results of MALDI-TOFMS. In the polymerization of bisphenol A epoxy resin with N, N`-dimethylethylenediamine, it was observed by MALDI-TOFMS that many kinds of polymers with high molecular weight were formed with an increase of reaction time. In this case, the LSIMS/MS observation of materials and the reaction products was carried out, the estimation structure could be confirmed from the measured results of MALDI-TOFMS. 19 refs., 8 figs.

  19. Diode laser pumped solid state laser. Part IV. ; Noise analysis. Handotai laser reiki kotai laser. 4. ; Noise kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Sakurai, H.; Seno, T.; Tanabe, Y. (Asahi Glass Co. Ltd., Tokyo (Japan))

    1991-06-10

    Concerning the second harmonic generation(SHG) of diode laser pumped solid state laser using a nonlinear optical material, the researches are carried out to pracitically apply to the optical pickup. Therefore, the reduction of output optical noise has become the important researching subject. The theoretical and experimental analyses of noise generating mechanism were carried out for the system in which Nd;YAG as the laser diode and KTP (KTiOPO {sub 4}) as the nonlinear optical crystal were used. The following findings for the noise generating mechanism could be obtained: The competitive interaction between the polarization modes was dominant noise mechanism in the high frequency range from 1 to 20MHz and the noise could be removed sufficiently by using the QWP(quarter wave plate). On the other hand, the noise observed in the low frequency range from 100 to 200kHz depended on the resonance length, agreed qualitatively with the theoretical analysis of the noise to the competitive longitudinal modes and agreed quantitatively with the noise generating frequency range. 10 refs., 13 figs., 1 tab.

  20. Defect detection of elevator wire rope by using wavelet analysis; Wavelet kaiseki ni yoru elevator rope no sonsho kenshutsu

    Energy Technology Data Exchange (ETDEWEB)

    Kaneda, M.; Kawata, A.; Hayashi, S. [Kansai University, Osaka (Japan). Faculty of Engineering; Tokui, K. [Mitsubishi Electric Building Techno-Service Co. Ltd., Tokyo (Japan)

    1998-10-31

    Detecting strand breakage and local wear of elevator wire rope uses currently a method using a rope tester. This method magnetizes a rope with electric magnet and detects defected part as leakage flux. Pulsed signals are issued from the defected part, variation in magnetic flux leakage due to rope swinging produces noise, and both get mixed together. Therefore, the detection is performed finally by visual check and palpation. This paper discusses a method that analyzes measurement data derived by the rope tester by using wavelet conversion, and detects the defected part automatically without being confused by noise. The pulsed signals generated from the defected part can be detected from noise by decomposing multiplex resolution using the Haar basis. As a result of the experiment, cases that may be overlooked in visual check because of S/N ratio being too small or the pulsed signals being too weak were all detected. 11 refs., 14 figs.

  1. Structure analysis of ultra-thin films. STM/AFM. Chousumaku no kozo kaiseki. STM/AFM

    Energy Technology Data Exchange (ETDEWEB)

    Nozoe, H; Yumura, M [National Institute of Materials and Chemical Research, Tsukuba (Japan)

    1994-03-30

    Fullerene (C60) and carbon nanotubes are expected as new carbon structures. This article describes the observation results of C60 and carbon nanotubes by means of STM (scanning tunnel microscope). The STM images of C60 thin films are illustrated, which have been obtained by annealing at 290 centigrade. It was confirmed that C60 monomolecular thin films are formed which conform to the substrate and have high regularity. The step height of C60 monomolecular thin films coincided with the step height of Cu (111) plane, which suggested that the step of films is reflected in that of Cu substrate. For the STM images under bias voltages, various images of C60 with three-fold axis of symmetry were observed. On the other hand, from STM observation of carbon nanotubes with diameter of about 30 nm which were separated and purified from the cathode deposits during the preparation process of C60, it was found that they have concentric multilayer structure. 18 refs., 7 figs.

  2. FY 1999 report on the results on analysis of protein functions; 1999 nendo tanpakushitsu kino kaiseki seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    This project is aimed at construction of the intellectual infrastructures for biotechnologies, in order to accelerate development of the Japanese technologies and activate their application to industries. Described herein are the FY 1999 results. These infrastructures are for functional analysis of protein which will be one of the key issues in genome analysis, and collection and analysis of biological information. This project includes a total of 9 research and development themes for four research categories: frequency analysis of gene expression (development of the gene expression profile database system for functional analysis of human genome, and analysis of the gene expression and protein functions by the ECA chip technology), function analysis by the biological model (high-performance analysis by the bio-project, database system for drug metabolizing enzymes, analysis of gene functions using mutant mice, and simple genome function analysis of murine individuals using the RNAi effect), protein expression (function validation of unknown human genes based on the useful biological model, and protein function analysis using multi-purpose destination vectors), and protein function prediction by the information science method. (NEDO)

  3. Electromagnetic analysis of HTSC by advanced fluxoid dynamics method; Kairyogata jisoku ryoshi doryokugakuho ni yoru koon chodendotai no denji kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Demachi, K.; Nakano, M.; Miya, K. [The Univ. of Tokyo, Tokyo (Japan). Graduate School of Engineering

    2000-05-29

    In this study, the improved fluxoid quantum dynamics method which applied the handling of the lattice in the lattice gas automaton method into the fluxoid quantum dynamics was developed. The saving of a memory capacity and the speedup of the calculation were carried out. Using a BSCCO single crystal which introduced a pinning center by the heavy ion irradiation as an analysis object, the validity of this technique was shown by the comparison with the experimental result. By the improved fluxoid quantum dynamics method, the space was made discrete by the triangular lattice in the two-dimensional system. The fluxoid quantum exists only on the lattice point, and received the force from the fluxoid quantum, the Meissner magnetic field and the pinning center in the circumference, and then moved to the 6 neighboring lattice points. Since the pattern of the positional relation of the fluxoid quantum was limited by the use of triangular lattice, the high-speed computation became possible by storing the interaction force into a database. The dependence for the radiation value of the torque in the axial type super-conductive magnet bearings was analyzed, and the possibility of the rotational loss control by the heavy ion irradiation was shown. (NEDO)

  4. Structural analyses of very large semi-submersibles in waves; Choogata hansensuishiki futai no harochu kozo oto kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Iijima, K.; Yoshida, K.; Suzuki, H. [The University of Tokyo, Tokyo (Japan)

    1997-08-01

    An analysis method in which the technique of a vehicle obtained when a three-dimensional singular point distribution method and Kagemoto`s mutual interaction theory are combined was expanded for the fluid area was proposed as the structural analysis of very large semi-submersibles in waves. A partial structure method is used for the structure. In a fluid area, the number of unknown quantities appearing in a final expression could be largely reduced by introducing the new concept of a group body. In this process, both hydro-elasticity and hydrodynamic mutual interaction are considered. As a result, floating bodies that could not be previously calculated can be modeled as a three-dimensional frame structure and the response analysis in waves can be carried out without damaging the accuracy. The calculation result is used as the input data required for analyzing the structural fatigue locally during structural design of very large semi-submersibles in the 3,000 (m) class. This study can present a series of procedures between the response analysis of very large floating bodies in waves and the structural design. 11 refs., 14 figs., 1 tab.

  5. Numerical analysis of macro-crack formation behavior within the lump coke; Cokes sonai kiretsu shinten kiko no kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Aoki, H; Sato, H; Miura, T [Tohoku University, Sendai (Japan). Faculty of Engineering

    1995-03-15

    The thermal stress analysis within lump coke was studied in order to investigate macro-crack formation and deformation behavior which strongly influence heat and mass transfer in a coke oven chamber. The dilatation of plastic layer, heating rate dependence of thermophysical and mechanical properties of coal/coke, creep in the plastic and semi-coke layers, macro-crack propagation and radiative heat transfer within the macro-crack were considered in an analytical model. The macro-crack propagation was determined from the estimated crack tip stress intensity factor, K{sub I}, at the macro-crack tip compared with the plane strain fracture toughness, K{sub IC}, through the unsteady-state calculation. Calculated results on crack formation and deformation behavior of lump coke were in good agreement with experimental observations in a laboratory-scale oven chamber. The analytical model could predict micro-crack formation within the lump coke normal to the heated wall and the coke surface close to the heated wall. 12 refs., 13 figs.

  6. Consideration on characteristics of faults distributed at around Fujigawa river mouth; Fujigawa kako shuhen ni okeru danso kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Iwashita, A; Misawa, Y [Tokai University, Tokyo (Japan)

    1997-10-22

    From the sonic prospecting on the ground, it was confirmed that faults distributed in the inner part of Suruga Bay extend near the Fujigawa river mouth. While, faults in the sea bottom were found by the sonic prospecting using a single air-gun. However, continuity of faults running from the land to the sea has not been reported. This paper describes the continuity of Fujigawa fault system running from the land to the sea around Fujigawa river mouth along the subduction zone of Philippine Sea Plate using single air-gun seismic reflection records. Locations of the faults can be expressed as fracture information of linearment obtained from the satellite remote sensing images, which agreed well with those found by the Active Fault Research Association. As a result of the image processing, they agreed distinctly with the topography of Fujigawa fault system. Thus, much more accurate analysis can be performed by comparing the regional information by the remote sensing with the sonic seismic reflection profiles. 3 refs., 2 figs.

  7. Fault analysis in the very shallow seismic reflection method. Part 3. Migration; Gokusenso hanshaho ni okeru danso kaiseki. 3. Migration

    Energy Technology Data Exchange (ETDEWEB)

    Nagumo, S; Muraoka, S; Takahashi, T [OYO Corp., Tokyo (Japan)

    1997-10-22

    Concerning the analysis of data obtained by the seismic reflection method, migration in the very shallow layer is discussed. When the dip angle of the reflection plane involved is disclosed by DMO conversion, the amount of migration (travelling sideways) can be calculated by use of simple geometrical formulas though on the presumption that the sector velocity is constant. Categorized into this technique are such methods as DMO conversion migration, direct dip migration, F-K method, and finite difference method. This means that waveforms are not damaged by migration processing although elongation occurs due to time base conversion. When it is taken into account that waveform distortion is generally grave in the migration related methods widely in use, this feature has to be said valuable in holding information on faults. This is especially advantageous in the very shallow layer because the amount of migration is proportionally larger when the level is deeper and, in addition, migration processing is useful when it is necessary to know more accurately the character of the fault plane. 8 figs.

  8. Reflector imaging by diffraction stacking with stacking velocity analysis; Jugo sokudo kaiseki wo tomonau sanran jugoho ni yoru hanshamen imaging

    Energy Technology Data Exchange (ETDEWEB)

    Matsushima, J; Rokugawa, S; Kato, Y [The University of Tokyo, Tokyo (Japan). Faculty of Engineering; Yokota, T [Japan National Oil Corp., Tokyo (Japan); Miyazaki, T [Geological Survey of Japan, Tsukuba (Japan)

    1997-10-22

    Concerning seismic reflection survey for geometrical arrangement between pits, the scattering stacking method with stacking velocity analysis is compared with the CDP (common depth point horizontal stacking method). The advantages of the CDP supposedly include the following. Since it presumes an average velocity field, it can determine velocities having stacking effects. The method presumes stratification and, since such enables the division of huge quantities of observed data into smaller groups, more data can be calculated in a shorter time period. The method has disadvantages, attributable to its presuming an average velocity field, that accuracy in processing is lower when the velocity field contrast is higher, that accuracy in processing is low unless stratification is employed, and that velocities obtained from stacking velocity analysis are affected by dipped structures. Such shortcomings may be remedied in the scattering stacking method with stacking velocity analysis. Possibilities are that, as far as the horizontal reflection plane is concerned, it may yield stack records higher in S/N ratio than the CDP. Findings relative to dipped reflection planes will be introduced at the presentation. 6 refs., 12 figs.

  9. Aircraft fatigue failures and duties of structural reliability analysis. Kokuki kozo no hiro hakai to kozo shinraisei kaiseki no yakuwari

    Energy Technology Data Exchange (ETDEWEB)

    Fujiwara, G [Japan Airlines Co. Ltd., Tokyo (Japan)

    1992-10-05

    The use of a commercial jet transport airplane over its life of 20 years has been increasing because of intestified competition after cancellation of the regulations. It is necessary that users of the airplane adopt such a positive way as they themselves maintain safety of their airplanes rather than they wait for feedback or technical instructions from manufacturers. This paper outlines the points at issue regarding the problem of fatigue strength which is fundamental to the safety problem, explaining by various examples that the fatigue strength problem includes phenomena of which theoretical elucidation has not been obtained. Consequently, some points to be paid attention to are cited. For instance, in the analysis of reliability in case of determining the period for initial inspection (safety life), reliability should be 95-99% which have been advised by Boeing and others, even if confidence level is 95% as usual In case of considering a fleet number in the reliability analysis, the fleet number should be reflected by grouping significant in fatigue analysis. 30 refs., 10 figs., 1 tab.

  10. Numerical analysis of a horizontal axis wind turbine rotor with winglets; Winglet wo motsu suiheijiku fusha no suchi kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Hasegawa, Y.; Kikuyama, K.; Imamura, H. [Nagoya University, Nagoya (Japan)

    1996-08-25

    The objective of present study is to show the aerodynamic effectivity of a horizontal axis wind turbine rotor blades with winglets by means of numerical analysis. The winglet used in this study is considered to be an inclined extension of the blade. For the numerical analysis a vortex lattice method with a free wake model was used because the model can be fitted to an arbitrary blade shape and needs no empirical parameter about wake geometry. The calculations were made on the flow field in the rotor wake and the rotor performance, and the results were compared between the rotors with and without winglets. In order to examine the structural effects, the flap bending moment was also compared. The results shows that small installation angle of winglets is found to cause a larger increase in the power coefficient and a smaller increase in the flap bending moment than radially extended rotor blades. 11 refs., 13 figs., 1 tab.

  11. Study of nozzle deposit formation mechanism for direct injection gasoline engines; Chokufun gasoline engine yo nozzle no deposit seisei kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Kinoshita, M; Saito, A [Toyota Central Research and Development Labs., Inc., Aichi (Japan); Matsushita, S [Toyota Motor Corp., Aichi (Japan); Shibata, H [Nippon Soken, Inc., Tokyo (Japan); Niwa, Y [Denso Corp., Aichi (Japan)

    1997-10-01

    Nozzles in fuel injectors for direct injection gasoline engines are exposed to high temperature combustion gases and soot. In such a rigorous environment, it is a fear that fuel flow rate changes in injectors by deposit formation on nozzles. Fundamental factors of nozzle deposit formation were investigated through injector bench tests and engine dynamometer tests. Deposit formation processes were observed by SEM through engine dynamometer tests. The investigation results reveal nozzle deposit formation mechanism and how to suppress the deposit. 4 refs., 8 figs., 3 tabs.

  12. Analysis of mixture formation of direct injection gasoline engine; Tonai funsha gasoline engine no kongoki keisei kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Kano, M; Saito, K; Basaki, M [Nippon Soken, Inc., Tokyo (Japan); Matsushita, S; Gono, T [Toyota Motor Corp., Aichi (Japan)

    1997-10-01

    On direct injection gasoline engine, in order to achieve good stratified combustion, the extremely advanced control of air-fuel mixture is required. For this purpose, the method of diagnosing the quality of the state of mixture formation in combustion chambers becomes necessary. In this research, the state of air-fuel mixture in the combustion chamber of a TOYOTA D-4 was analyzed in space and time by visualization, A/F multi-point measurement and A/F high response measurement, thus the effects that injection timing, swirl and fuel pressure exerted to mixture formation were elucidated. 3 refs., 17 figs., 1 tab.

  13. Analysis of axial behavior of three piece oil control ring; Kumiawase oil ring no jikuhoko kyodo no kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Tateishi, Y; Fujimura, K; Hitosugi, H [Nippon Piston Ring Co. Ltd., Tokyo (Japan)

    1997-10-01

    It is considered that the reduction of oil control ring tension is a major problem in reducing the friction-loss of internal combustion engines. The authors have successfully developed a calculating method for the axial behavior prediction of a three piece type oil control ring as a method used in reduction of lube-oil consumption when lower tension ring is used. By means of the method, the authors found that the effect in reduction of lube-oil consumption was able to be expected by optimizing design parameters of the oil ring, the tension and the seating tab angle of expander-spacer, and the gas pressure on the 3rd land. 3 refs., 14 figs.

  14. Analysis of fuel spray characteristics for premixed lean diesel combustion; Kihaku yokongo diesel kikan ni okeru nenryo funmu kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Sasaki, S; Harada, a; Miyamoto, T; Akagawa, H; Tsujimura, K

    1997-10-01

    Premixed lean diesel combustion (PREDIC) makes it possible to achieve low NOx emission. It is an important factor to make the homogeneous spray formation for PREDIC. In this paper presents I the effect of the spray dispersion on emission characteristic were analyzed with the spray observation and engine test. Pintle type nozzle, which has different feature from orifice type nozzle, are used to form the hollow cone spray. As a result, the pintle type nozzle having grooves to generate the swirl flow, makes the reduced penetration in comparison with the hole nozzle under low ambient gas pressure. And it could improve THC, CO emissions at low NOx emission condition. 7 refs., 12 figs., 1 tab.

  15. CFD analysis of flow in engine compartment of large urban bus; Ogata bus no engine room nai nagare kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Hoshino, H; Otake, M; Iioka, K [Nissan Diesel Motor Co. Ltd., Saitama (Japan); Sato, K [Subaru Research Center Co. Ltd., Tokyo (Japan)

    1997-10-01

    A CFD simulation was performed to analyze the air flow in the engine compartment of a large urban bus. The conventional simulation technique takes a long time to perform the parameter study of a complex engine compartment shape. In this study, the use of orthogonal grids made modeling the engine compartment easy, so parameter study on modification of the engine compartment structure could be conducted in a short time. Thus this simulation enables engineers to more clearly understand the air flow patterns in the engine compartment, and to get guidlines for modifying the compartment structure to improve the cooling performance. 1 ref., 12 figs.

  16. Characterization of surface layers of aluminum alloys for automobile body panels; Jidoshayo aluminium gokin no hyomen kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Mizuno, K; Takagi, Y [Nippon Steel Corp., Tokyo (Japan)

    1996-03-29

    This paper reports analytical examples, on an oxidized film on the surface of aluminum alloys for automobiles, using the conventional method for a surface analysis or a new method entirely different from it. For example, (1) a new method was proposed which evaluated the thickness of MgO layers on the surface of Al-Mg alloy by means of a colorimeter. In the case where the thickness of the oxidized film was several tens of nanometers or less, the chromatic value of L, b, etc., and the thickness of the films were in one-to-one correspondence to each other; therefore, the MgO film was easily estimated non-destructively by measuring the chromatic values of the surface. (2) An analysis was made on the state of adhesion of the organic matters in the oxidized film on Al-Mg-Si alloy by means of an angle-resolved XPS (X-ray photoelectron spectroscopy) depth analysis. Consequently, it was elucidated that a fatty film adhered with hydrophilic groups faced to the oxidized surface and with hydrophobic groups faced to the outside, and that this adhered fatty acid also formed a metallic soap by a heat treatment, deteriorating the fattiness. Further, the paper also reports on the analysis of crystal structures on the surface layer with the use of GIXD (grazing incidence-angle X-ray diffraction). 22 refs., 15 figs.

  17. Photometric analysis on concentration characteristics of Fresnel lenses; Fotometoriho wo mochiita Fresnel lens no shuko tokusei kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, A [Tokyo University of Agriculture and Technology, Tokyo (Japan)

    1997-11-25

    Light concentration characteristics of Fresnel lenses were analyzed by using photometry. Light concentrating systems include a reflective system represented by a rotary parabolic mirror, and a refractive system represented by the Fresnel lens. The refractive system has a focused section broadened as much as the dispersion effect in association with refraction, and cannot derive a focus with high magnification as compared with the reflective system which can achieve it. The refractive system causes reduction in collected light intensity to about half on a parax, hence a large amount of loss. However, the system can be made available inexpensively due to mass production by using mold formation. Although it is difficult to utilize all of the light, 95% of the received radiation is concentrated in an opening area with a radius of about 4G (G is a radius of an image of solar light at a focus plane which passes through the center of a Fresnel lens). The average magnification of light concentration at this time in the opening area reaches 390 times. When a 3-D compound parabolic concentrator (CPC) with a radius of 4G is placed on a lens focus as a secondary light concentrator, the final magnification of light concentration shows a value of about 2700 times, whereas restoration of 39% is possible, as compared with a rotary parabolic mirror. The system has sufficient possibility to be used for high-temperature light concentration. 3 refs., 5 figs., 1 tab.

  18. Water quality and water pollution sources in Poyang lake, China; Poyang ko ni okeru suishitsu chosa to odakugen kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Ito, M. [Shin-Nippon Meteorological and Oceanographical Consultant Co. Ltd., Tokyo (Japan)

    1996-01-10

    This paper summarizes the current status of water quality and pollution sources in Poyang Lake in China. The lake is located in Chianghsi Province of China, and a largest fresh water lake in China that flows out into the Yangtze river. The basin is surrounded by mountains on three sides and faces the Yangtze on one side, whereas the plains formed by the lake and the rivers flowing in extends in the center of the basin. The plains around the lake has the city of Nanchang, the capital of the province, the city of Jiujiang (both cities have a population of about 4 million, respectively), and four other cities with a size of one million people including Jingdezhen. Water supply system in the basin is used in a 37% area of the urban areas, and no sewage facilities of whatsoever are available as of 1991. The lake has COD of about 3 mg{times}1/l. No severe pollution by organic matters is seen. While the T-P concentration is at a high level, PO4-P is low. Majority of phosphorus flowing into the basin exists in the form trapped in soil particles. In order to maintain the current water quality in the future, waste water treatment is required in the basin. Construction of an oxidation pond in the vast land exposed during the drought period is a measure that can be tackled relatively easily. 1 fig., 4 tabs.

  19. Three-dimensional analysis of the magnetic structure in Hokkaido, Japan; Hokkaido no sanjigen jiki kozo kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Makino, M [Geological Survey of Japan, Tsukuba (Japan)

    1996-10-01

    The magnetic structure in Hokkaido was quantitatively analyzed by the magnetic anomaly distribution. This paper describes its characteristics. Detection of structural boundaries and 3-D analysis of double-layer structure were conducted for the regional magnetic data in a region with about 500 km square. There was not so large difference in patterns of magnetic anomaly distribution between the case that the direction of magnetization was set at 45{degree} to the west during the geomagnetic conversion according to Segawa and Oshima and the case that it was set as same as the current geomagnetic direction. The method of Blakely and Simpson was useful to detect the boundaries of magnetic structures. The structural boundaries obtained were more linear than the iso-magnetic contour lines. A new method has been conceived in which the approximation of 3-D magnetic structure analysis can be deduced, and the irregularity of magnetic basement can be determined by the repeated calculation. In practice, this method was applied to the magnetic data in the whole Hokkaido. The calculation was stably converged. It was found that the magnetic structure obtained in the Kamuikotan/Ishikari-Kitakami magnetic belt exhibited a fault structure having steep slopes accompanied by the basin structure in the western boundaries. 19 refs., 6 figs.

  20. Relation between frequency of seismic wave and resolution of tomography; Danseiha tomography kaiseki ni okeru shuhasu to bunkaino no kankei

    Energy Technology Data Exchange (ETDEWEB)

    Fujimoto, M; Watanabe, T; Ashida, Y; Sassa, K [Kyoto University, Kyoto (Japan). Faculty of Engineering

    1997-05-27

    With regard to the elastic wave exploration, discussions have been given on the relationship between frequency and resolution in P-wave velocity tomography using the initial travel time. The discussions were carried out by using a new analysis method which incorporates the concept of Fresnel volume into tomography analysis. The following two arrangements were used in the calculation: a cross hole arrangement, in which seismic source and vibration receiving points were arranged so as to surround the three directions of a region extending 250 m in the horizontal direction and 500 m in the vertical direction, and observation is performed between two wells, and a permeation VSP arrangement in which the seismic source is installed on the ground surface and receiving points installed in wells. Restructuring was performed on the velocity structure by using a total of 819 observation travel times. This method has derived results of the restructuring according to frequencies of the seismic source used for the exploration. The resolution shown in the result of the restructuring has become higher as elastic waves with higher frequency are used, and the size of the structure identified from the restructuring result has decreased. This fact reveals that sufficient considerations must be given on frequencies of elastic waves used according to size of objects to be explored. 4 refs., 4 figs.

  1. Fault analysis in the very shallow seismic reflection method. 2; Gokusenso hanshaho ni okeru danso kaiseki. 2

    Energy Technology Data Exchange (ETDEWEB)

    Nagumo, S; Muraoka, S; Takahashi, T [Oyo Corp., Tokyo (Japan)

    1997-05-27

    Fault analysis is required in addition to the ordinary process of structural analysis (CDP stacking) for the examination of discontinuity in the reflection horizon in question. The fault shape restoration principle is that the reflection point of a reflection wave observed at a certain receiving point is on an ellipse with the shock point and receiving point at its focal points and that the sum of the distances between the reflection point and the focal points is equal to the reflection wave propagation time. The DMO velocity is worked out by calculation using the positive travel time and inverse travel time from the common reflection surface. When the reflection surface is inclined by {theta}, the average interval velocity/cos{theta} is called the DMO velocity. When the reflection surface inclination and the average interval velocities are determined separately in this way, the position of the reflection point may be worked out, and this enables the calculation of the amount of migration (lateral movement). The reflection wave lineups carried by the original record are picked up one by one, and the average interval velocities are treated very prudently. After such a basic DMO conversion treatment, the actualities of the fault are described fairly correctly. 3 figs.

  2. Analysis and evaluation for practical application of photovoltaic power generation system. Analysis and evaluation for thin substrate polycrystalline solar cells (compound semiconductors and their fabrication technologies); Taiyoko hatsuden system jitsuyoka no tame no kaiseki hyoka. Usumaku taiyo denchi jitsuyoka no tame no kaiseki hyoka (kagobutsu taiyo denchi zairyo oyobi seisaku gijutsu no kaiseki hyoka)

    Energy Technology Data Exchange (ETDEWEB)

    Oyagi, H; Okada, Y; Yamaguchi, H; Shiota, T; Kuroda, S; Igarashi, O; Tanino, H; Makita, Y; Yamada, A; Kimura, S; Ohara, A; Niki, S; Shibata, H; Fons, P [Electrotechnical Laboratory, Tsukuba (Japan)

    1994-12-01

    Described herein are the results of the FY1994 research program for analysis and evaluation for thin-film compound semiconductor solar cells. The study on epitaxial growth and optical properties of the thin films of CuInSe2 and CuGaSe2 evaluates the thin epitaxial films grown under various conditions, showing morphology of the defects at the interface of heteroepitaxial growth. These results are used to set the growth conditions under which a thin film of high luminescence by exciter recombination is produced. The study also gives information of luminescence transition in the vicinity of the band ends and of energy level between the bands. The study on structural analysis of the epitaxially grown thin films of CuInSe2 investigates dependence of lattice constants of the MBE-grown CIS layer on film thickness by the X-ray diffractometry based on the bond method. The study on epitaxial growth by the Se(CH3)2-halogen transfer method tests epitaxial growth of the single-crystalline Mo on a substrate of single-crystalline sapphire. 5 figs.

  3. FY 1998 report on the results of the research and development of fundamental technologies for superconductor applications; 1998 nendo chodendo oyo kiban gijutsu kenkyukaihatsu seika hokokusho. Chodendo oyo kiban gijutsu keknyu kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-05-01

    As to the research on the superconductor manifestation mechanism, Y123 monocrystal which was partially replaced with Zn and Ni was manufactured, and it was made clear that the addition of these impurities greatly change anisotropy of superconductors. It was made clear that instability of lattice and magnetism is included in high temperature superconductor. Also made clear was an important role in the Nb/Ba replacement in existence of magnetic flux melting phase transfer and the magnetic field induced pinning effect. The manufacture of Y123 bicrystal membrane was successful by the liquid phase epitaxy method. The manufacture of non-copper base K-Bi-O new superconductor was successful by the ultra-high pressure synthesis method. The stabilized process was established for large size crystals of 15-20mm square in Y base and of 20-25mm square in Nd base. Also successful was the growth by LPE method of crystal with thick membrane of 20mm x 20mm x 10{mu}m on the MgO monocrystal substrate. The non-bicrystalization of Y base Nd base monocrystal was successful, and the peak phenomenon control in Jc-H was found out. By neutron irradiation, the acquisition magnetic field of 3.7T at 77K was achieved using bulk Y base 123 material with diameter of 3cm. And, the critical current density of 60,000 A/cm{sup 2} was achieved at 77K and 3T. (NEDO)

  4. Microbiological Safety Assessment of Fermented Cassava Flour “Lafun” Available in Ogun and Oyo States of Nigeria

    Directory of Open Access Journals (Sweden)

    A. O. Adebayo-Oyetoro

    2013-01-01

    Full Text Available The microorganisms involved in the fermentation and spoilage of fermented cassava flour were investigated. The water samples used at the different processing sites were also investigated to determine their safety status. There was predominance of Staphylococcus aureus, Aspergillus spp., and Escherichia coli in all samples. Coliforms were observed to be present in all of the processing water. In the fermented cassava flour, the total bacterial count ranged between 4.9×106 cfu/mL from Eleso, Bakatari, and Oja Odan processing sites and 8.10×106 cfu/mL in Eruku processing site. The majority of the microorganisms involved in the spoilage of “lafun” were found to be Aspergillus niger which ranged between 4.6×105 cfu/mL in Eleso and 8.1×105 cfu/mL in Kila. The control sample prepared in the laboratory had a low microbial load compared to samples collected from various sites and markets.

  5. An observational study of road safety around selected primary schools in Ibadan municipality, Oyo State, Southwestern Nigeria.

    Science.gov (United States)

    Sangowawa, Adesola O; Adebiyi, Akindele O; Faseru, Babalola; Popoola, Olusola J

    2012-01-01

    Child pedestrians have been identified as vulnerable road users. Although walking as a means of transport has health and other benefits, it exposes children to the risk of road traffic injuries. This study was conducted to assess the availability of road safety features around government-owned primary schools in Ibadan municipality. A multistage sampling technique was used to select 46 of the 74 schools in the study area. Some (11) of the selected schools were sited within the same premises and shared a common entrance; thus a total of 35 school premises were eventually observed. Trained research assistants observed the school environment around the selected schools for road safety features such as location of schools, presence of "school", "child crossing" and "speed limit" road signs, and presence of traffic calming devices (road bumps or zebra crossing). Five (14%) of the schools were located on major roads and eight (23%) had road signs indicating that a school was nearby. Seven (20%) had road bumps close to the school, 15 (43%) had a warden who assisted children to cross, and none had a zebra crossing. Five (14%) schools had pedestrian sidewalks. The study revealed that the environment around a number of the observed schools in the municipality compromised the pupils' road safety. The local government, school authorities, parents, and road safety professionals need to institute definite measures to enhance the road safety environment around schools in the municipality.

  6. Research of fragranced air, environmental aroma, to human and its application. Kankyo hoko no koka to sono oyo

    Energy Technology Data Exchange (ETDEWEB)

    Hashimoto, S. (Shimizu Construction Co. Ltd., Tokyo (Japan))

    1991-06-01

    The effect of lemon, jasmine and lavender aroma on people was studied through environmental aroma experiments by 270 subjects in a meeting room for two months. As a result, the high percentage of positive responses was obtained on the sense of air cleanliness and efficiency of meetings, and a statistical significance was, in particular, obtained in the case of lemon as smoking was permitted. It was suggested that aroma had physiological and phychological effect even under conditions where the subjects were not necessarily aware of aroma. The effect of the same three aromas was also studied through experiments by 13 subjects in a VDT room for one month. As a result, the number of keypunch errors decreased in every aroma although punching speeds decreased slightly, and lemon showed a significant difference among three aromas. Based on these experimental results, the aroma generator was developed, and more than 30 environmental aroma systems combined with air conditioning ducts have been installed in Japan. 20 refs., 5 figs., 6 tabs.

  7. Novel methodology for the production of carbon nanotubes and their application; Atarashii kabon nanochubu no seizo to sono oyo

    Energy Technology Data Exchange (ETDEWEB)

    Kyotani, T; Tomita, A [Tohoku Univ., Sendai (Japan)

    1996-11-01

    Carbon nanotubes (CNTs) are highly evaluated together with fullerene for their potential use as novel materials. Currently, CNTs can be synthesized by arc discharge with carbon electrodes or by thermal decomposition of hydrocarbons in gas phase. However, neither of these processes afford selectively CNTs homogenous in diameter and length. The authors found out that homogeneously sized CNTs are available by using, as templates for depositing carbon, linear micro-pores in oxide film formed by anodic oxidation of aluminum. The diameter, length and density of micro-pores can be easily controlled by changing conditions for electrolysis. Carbon is deposited onto the inner wall of the pore by thermal decomposition of propylene at 800 centigrade in a quartz reaction tube. Thereafter, oxide film is removed by dissolution. CNTs thus obtained are open in both ends and easy for insertion of heterogeneous materials such as metals into pore space. A platinum/CNT one-dimension complex was prepared by inserting platinum. Since complexes such as this may have novel properties that bulk materials would not show, they are expected to be used as novel semiconductors or catalysts. 7 refs., 4 figs.

  8. Determinants of adoption of vitamin A bio-fortified cassava variety among farmers in Oyo State, Nigeria

    Directory of Open Access Journals (Sweden)

    O. O. Ologunde

    2017-01-01

    Full Text Available The success of any agricultural innovation depends on its adoption by farmers. The study evaluates the determinants of adoption of vitamin A bio-fortified cassava variety among farmers by investigating the level of adoption and determinants of adoption among farmers. Three stages of random sampling procedure were used to select 240 cassava farmers. The data obtained were analyzed with descriptive statistics and a logit regression model. The study revealed that the level of adoption of vitamin A bio-fortified cassava variety is low (38.72%. The study also revealed that access to media, contact with extension agents, access to vitamin A bio-fortified cassava stem, amongst others, are the determinants of adoption of vitamin A bio-fortified cassava variety in the study area. It is therefore recommended that awareness about the new cassava technology should be prioritized to sensitize the farmers, and stems of these cassava varieties should be readily made available to farmers to take advantage of the benefit of the innovation.

  9. Comparison of Knowledge on Diarrheal Disease Management between Two Types of Community-Based Distributors in Oyo State, Nigeria

    Science.gov (United States)

    Ande, Oluyinka; Oladepo, Oladimeji; Brieger, William R.

    2004-01-01

    Community-based distributors (CBDs) have been trained and utilized to promote a variety of health commodities. In addition, a variety of different types of community residents have been trained ranging from traditional birth attendants (TBAs) to patent medicine vendors. A training programme for CBD agents in the Akinyele Local Government Area of…

  10. Evaluation of directly observed treatment short courses at a secondary health institution in Ibadan, Oyo State, Southwestern Nigeria.

    Science.gov (United States)

    Adegoke, Olajire A; Orokotan, Olalekan A

    2013-12-01

    To evaluate the success rate of tuberculosis intervention programme at a specialist hospital in Ibadan, Nigeria through a retrospective study as well as carry out physicochemical evaluation of anti-tuberculous agents as a way of eliminating drug-related failure. The retrospective study involved the use of quarterly tuberculosis central register at the Government Chest Hospital, Ibadan between 1st quarter (2003) to 4th quarter (2009). Relevant data were extracted from these register with the aid of data collection forms. The basic physicochemical analyses of the drugs given to the patients were also carried out using the International Pharmacopoeia methods. All the drugs examined for their physicochemical properties passed the International Pharmacopeia recommended tests. A total number of 1 260 patients enrolled at the hospital were assessed through case notes. This comprises of 59.4% males of which 69.23% new cases were also males. There was a significant (PFailure treatment outcomes such as positive (1.51%), deaths (8.73%), defaulted (3.33%) and transferred out (5.95%) were recorded though not statistically significant (P>0.05). Failure rates in all categories were higher in males than females (P>0.05). More enlightenment and counseling is still required to meet up with the target for TB control. Copyright © 2013 Hainan Medical College. Published by Elsevier B.V. All rights reserved.

  11. Nursing documentation: experience of the use of the nursing process model in selected hospitals in Ibadan, Oyo State, Nigeria.

    Science.gov (United States)

    Ofi, Bola; Sowunmi, Olanrewaju

    2012-08-01

    The descriptive study was conducted to determine the extent of utilization of the nursing process for documentation of nursing care in three selected hospitals, Ibadan, Nigeria. One hundred fifty nurses and 115 discharged clients' records were selected from the hospitals. Questionnaires and checklists were used to collect data. Utilization of nursing process for care was 100%, 73.6% and 34.8% in the three hospitals. Nurses encountered difficulties in history taking, formulation of nursing diagnoses, objectives, nursing orders and evaluation. Most nurses disagreed or were undecided with the use of authorized abbreviations and symbols (34.3%, 40.3% and 69.5%), recording errors that occurred during care (37.1%, 56.1% and 52.2%) and inclusion of change in clients' condition (54.3%, 56.1% and 73.8%). Most nurses appreciated the significance of documentation. Lack of time, knowledge and need for extensive writing are the major barriers against documentation. Seventy-seven point four per cent of the 115 clients' records from one hospital showed evidence of documentation, no evidence from the other two. Study findings have implications for continuing professional education, practice and supervision. © 2012 Blackwell Publishing Asia Pty Ltd.

  12. Prevalence of Toxoplasma gondii and HIV infection among pregnant women in Ibadan North Local Government, Oyo State.

    Science.gov (United States)

    Awobode, H O; Olubi, I C

    2014-12-01

    Toxoplasmosis, a disease caused by Toxoplasma gondii poses a risk of congenital infection during pregnancy in infected women. The disease poses a threat of ocular and neurological sequelae in congenitally ilfected infants and HIV patients; however, there is little valuable information on its prevalence in Ibadan. A cross sectional study of pregnant women attending antenatal care in three primary healthcare centres in Ibadan was carried out. 179 women were screened for T gondii infection using PCR, 83 of these were also screened for HIV. Forty nine (27.4%) were positive for T gondii, and 2(2.4%) were HIV positive (P = 0.002, OR = 0.28, CL = 95%). 27 (15.1%) of the infected women were in third trimester, with 20 (11.2%) and 2 (1.1%) in second and first trimester respectively. 18 (10.1%) positive cases were identified among the primigravidas and 31 (17.2%) among the multigravidas. Risk factors associated with Toxoplasma infection were assessed, and the source of drinking water and the types of animals around habitation were found to be significantly associated with the presence of Toxoplasma infection (P = 0.002, OR = 2.109 and P = 0.004, OR = 1.693 respectively). The high prevalence among women in third trimester may indicate high risk of congenital infection, and the significant association found between the source of drinking water and infection suggests environmental contamination as a major possible mode of infection. The need to educate pregnant women about the transmission mechanisms of T. gondii, and the effects of the infection on neonates and babies is pertinent in order to effectively control Toxoplasma infection.

  13. Seroprevalence of parvovirus B19 IgG and IgM antibodies among pregnant women in Oyo State, Nigeria.

    Science.gov (United States)

    Abiodun, Iyanda; Opaleye, Oluyinka Oladele; Ojurongbe, Olusola; Fagbami, Ademola Hezekiah

    2013-12-15

    Human parvovirus B19 causes a wide range of complications in pregnant women including abortion, severe fetal anemia, non-immune hydrops fetalis, and even intrauterine fetal death. However, there is a dearth of information on the prevalence of the virus among pregnant women in southwestern Nigeria. Blood samples were collected from 231 pregnant women and screened for antibodies to human parvovirus B19 IgM and IgG using an enzyme immunosorbent assay kits. Of the 231 women, 31 were in their first trimester, 146 were in their second trimester, and 54 were in their third trimester. Forty-five (20%) were positive for parvovirus B19 IgG antibodies, 10 (4%) were positive for parvovirus B19 IgM antibodies, and 176 (76%) had no detectable parvovirus B19 antibodies. Twenty-eight (19%) of the 146 pregnant women in their second trimester were positive for parvovirus B19 IgG antibody while three (2%) of the 146 were positive for parvovirus B19 IgM antibody. It is evident that there is a high prevalence of human parvovirus B19 among pregnant women in south-western Nigeria. This suggests that there is an active transmission of the virus in the community; it is therefore necessary to conduct more studies on the virus in pregnant women in Nigeria to ascertain its effect on the fetus.

  14. E-banking services impact and customer satisfaction in selected bank branches in Ibadan metropolis, Oyo state, Nigeria

    Directory of Open Access Journals (Sweden)

    Haadi Babatunde Asiyanbi

    2018-09-01

    Full Text Available This study perused the impact of E-banking services on customer satisfaction of selected bank customers in bank branches located in Challenge, Dugbe, Agbeni, Gbagi, Ojoo, and Secretariat districts in Ibadan metropolis. The study employed a cross-sectional survey design and convenience sampling technique. One hundred (100 bank customers were surveyed through a self-report questionnaire. Four research questions and two hypotheses were tested using Pearson correlation analysis and, t-test for independence at p≤ 0.05. The results revealed high utilization of electronic banking products (ATM (98%, internet banking (85%, electronic transfer (97%. Constraints experienced include internet network failure, bank fraud and business loss due to failed e-transactions. Customers were satisfied with e-banking due to its cashless nature, cash accessibility, saves time from bank visitation and seamless transactions. The study exhibited that customers used and were glad with e-banking products. Customers’ segmentation and more investment in e-banking infrastructure were advised for promoting electronic banking services.

  15. Immediate data access system for LHD experiments

    International Nuclear Information System (INIS)

    Emoto, M.; Iwadare, Y.; Nagayama, Y.

    2004-01-01

    Several kinds of computer systems are used to perform large helical device (LHD) experiments, and each produces its own data format. Therefore, it has been difficult to deal with these data simultaneously. In order to solve this problem, the Kaiseki server was developed; it has been facilitating the unified retrieval of LHD data. The data acquired or analyzed by various computer systems are converted into the unified ASCII format, or Kaiseki format, and transferred to the Kaiseki server. With this method, the researchers can visualize and analyze the data produced by various kinds of computers in the same way. Because validations are needed before registering on the Kaiseki server, it takes time to make the validated data available. However, some researchers need data as soon as it is gathered in order to adjust their instruments during the experiments. To satisfy this requirement, a new visualization system has been under development. The new system has two ways to visualize the data as physical values from the raw data. If the conversion task is not complex, the NIFSscope, a visualization tool, converts the raw data into physics data by itself. If the task is too complex to handle, it asks the ANACalc server to make physics data. When the ANACalc server receives a request, it delegates calculation programs to convert the acquired data into physics data. Because the interfaces between the server and the calculation processes are independent of programming languages and operating systems, the calculation processes can be placed on different computers and the server load can be reduced. Therefore, the system can respond to changes in requirements by replacing the calculation programs, and can easily be expanded by increasing the number of calculation servers

  16. Efficacy of nitric oxide, with or without continuing antihypertensive treatment, for management of high blood pressure in acute stroke (ENOS)

    DEFF Research Database (Denmark)

    Bath, Philip M W; Woodhouse, Lisa; Scutt, Polly

    2015-01-01

    BACKGROUND: High blood pressure is associated with poor outcome after stroke. Whether blood pressure should be lowered early after stroke, and whether to continue or temporarily withdraw existing antihypertensive drugs, is not known. We assessed outcomes after stroke in patients given drugs......·91-1·13; p=0·83), and with continue versus stop antihypertensive drugs OR was 1·05 (0·90-1·22; p=0·55). INTERPRETATION: In patients with acute stroke and high blood pressure, transdermal glyceryl trinitrate lowered blood pressure and had acceptable safety but did not improve functional outcome. We show...

  17. Study about the effect of microgravity on biofunctions; Seitai kino eno bisho juryoku no eikyo ni kansuru kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    A study is made for the elucidation of the effect of microgravity on biofunctions. The protoplast of shiitake is exposed to microgravity and then cultured, and a significant difference occurs. The rate of colony formation by cell fusion in the test sector is found to be two times higher than that in the control sector. When swimming ciliates which are unicellular are suddenly exposed to microgravity, their swimming speeds changed differently according to the direction of swimming. When a mouse subjected to acupuncture for three days is exposed to microgravity, its water metabolism and excretory function are enhanced. A mouse treated with Chinese medicine reacts in the similar way. The change due to microgravity in the amount of acetylcholine in the hypothalamus is found characteristically time dependent. Mice infected with lethal herpes viruses just after exposure to microgravity die at a rate in proportion to the number of exposures and to the amount of viruses given. The migration speed of chemical stripes in case of a gel-base BZ (Belousov-Zhabotinsky) reaction under microgravity is equal to that on the ground. The trigger wave migration speed in case of a water solution-base BZ reaction under microgravity is reduced to approximately 80% of the speed on the ground. 12 refs., 31 figs., 3 tabs.

  18. Report to the Nuclear Regulatory Commission from the staff panel on the Commission's determination of an Extraordinary Nuclear Occurrence (ENO)

    International Nuclear Information System (INIS)

    1980-01-01

    The Panel finds that the first criterion, pertaining to whether the accident caused a discharge of radioactive material or levels of radiation offsite as defined in 10 CFR 140.84, has not been met. It further finds that there is presently insufficient information to support any definitive finding as to whether or not the second criterion, relating to damage to persons or property offsite as defined in 10 CFR 140.85, has been met. Since the Panel has not found that both criteria have been met, it recommends that the Commission determine that the accident at Three Mile Island did not constitute an extraordinary nuclear occurrence

  19. Optimum design of automobile seat using statistical design support system; Tokeiteki sekkei shien system no jidoshayo seat eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Kashiwamura, T [NHK Spring Co. Ltd., Yokohama (Japan); Shiratori, M; Yu, Q; Koda, I [Yokohama National University, Yokohama (Japan)

    1997-10-01

    The authors proposed a new practical optimum design method called statistical design support system, which consists of five steps: the effectivity analysis, reanalysis, evaluation of dispersion, the optimiza4ion and evaluation of structural reliability. In this study, the authors applied the present system to analyze and optimum design of an automobile seat frame subjected to crushing. This study should that the present method could be applied to the complex nonlinear problems such as large deformation, material nonlinearity as well as impact problem. It was shown that the optimum design of the seat frame has been solved easily using the present system. 6 refs., 5 figs., 5 tabs.

  20. Adaptation of topology optimization on truck-structure; Kinshitsukaho ni yoru iso saitekika shuho no truck kozo eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Tachibana, H; Kojima, A; Chiba, S [Mitsubishi Motors Corp., Tokyo (Japan)

    1997-10-01

    An optimization using the homogenization method has been applied to a truck-structure on the concept design stage. A truck-structure is grouped into 3 classes (thin plate structure , thick plate structure and solid structure), then example, effectiveness and method for the application for the purpose of weight reduction , high rigidity and high eigen-frequency are introduced. 3 refs., 24 figs., 1 tab.

  1. Role of iNOS and eNOS expression in a group of Egyptian diabetic and nondiabetic nephropathy patients

    Directory of Open Access Journals (Sweden)

    Mayssa I. Aly

    2013-01-01

    Conclusion The presence of iNOS is associated with tubular damage resulting in renal failure. The upregulation of NO in diabetes mellitus type 2 may explain the endothelial dysfunction that is associated with almost all diabetic complications.

  2. Kinnisvaraäri ajas Pärnu linnajuhid omavahel tülli / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2008-01-01

    Pärnu linnavolikogu esimees Ahti Kõo peab ebaeetiliseks linnapea Mart Viisitamme ja spordiseltsi Põhjakotkas juhatuse esimehe Ivar Hallopi vahel sõlmitud ühtse kavatsuse protokolli. Ilmunud ka Pärnu Postimees 17. nov. lk. 1

  3. Pärnu leivatööstusest võib saada sakslaste allhankija / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2006-01-01

    Pere Leib Tootmine plaanib kolida leiva-saia tootmise suuremas osas Tartusse ja keskenduda Pärnus eksporttoodete valmistamisele Saksa turule. Arvamust avaldab Pere Leib Tootmise juhatuse liige Eero Mikenberg

  4. Rapala landitehas püüdis tänavugi suurima kala / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2006-01-01

    Maailmakuulsa landitootja Rapala Pärnus Reldori tööstuskülas asuv tehas pääses teist aastat järjest Pärnumaa aasta ettevõtete edetabeli etteotsa. Diagramm: Rapala Eesti ASi majandustulemused. Vt. samas: Pärnumaa ettevõtete tipp 50

  5. Häädemeeste vallavanem jäi kihutamise pärast jalameheks / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2006-01-01

    Ilmunud ka: Postimehes 9. nov. lk. 5 lüh.Korduva kiiruseületamisega silma paistnud Häädemeeste vallavanem Urmas Aava peab viimase kihutamise eest kuuks sõiduõiguseta jätmist liiga karmiks karistuseks

  6. MiR-21 is induced in endothelial cells by shear stress and modulates apoptosis and eNOS activity

    International Nuclear Information System (INIS)

    Weber, Martina; Baker, Meredith B.; Moore, Jeffrey P.; Searles, Charles D.

    2010-01-01

    Mechanical forces associated with blood flow play an important role in regulating vascular signaling and gene expression in endothelial cells (ECs). MicroRNAs (miRNAs) are a class of noncoding RNAs that posttranscriptionally regulate the expression of genes involved in diverse cell functions, including differentiation, growth, proliferation, and apoptosis. miRNAs are known to have an important role in modulating EC biology, but their expression and functions in cells subjected to shear stress conditions are unknown. We sought to determine the miRNA expression profile in human ECs subjected to unidirectional shear stress and define the role of miR-21 in shear stress-induced changes in EC function. TLDA array and qRT-PCR analysis performed on HUVECs exposed to prolonged unidirectional shear stress (USS, 24 h, 15 dynes/cm 2 ) identified 13 miRNAs whose expression was significantly upregulated (p · ) production. These data demonstrate that shear stress forces regulate the expression of miRNAs in ECs, and that miR-21 influences endothelial biology by decreasing apoptosis and activating the NO · pathway. These studies advance our understanding of the mechanisms by which shear stress forces modulate vascular homeostasis.

  7. Estimation of the charge quantity from solar cell to battery; Taiyo denchi ni yoru chikudenchi eno juden yosoku

    Energy Technology Data Exchange (ETDEWEB)

    Tsutsumi, K; Nishitani, M [Daiichi University, College of Technology, Kagoshima (Japan)

    1996-10-27

    In performing an experiment of running a small electric vehicle by installing solar cells in it and by charging the storage battery at a specific voltage, an estimation was made on the charge quantity to the battery for each solar altitude and inclination of a module at different hours. The solar altitude was determined at Daiichi University, College of Technology, according to the month and the time of day from a formula using day-declination and time equation of a chronological table of science. The quantity of global solar radiation was determined by resolving the solar radiation into its direct and diffuse components on the basis of the extra-terrestrial solar radiation quantity with the change in radius vector taken into consideration; and then, the global solar radiation on the inclined face was obtained from the angle of inclination and incidence. On the roof of a Daiichi University building, solar cell modules were installed facing north and south at 0{degree}, 30{degree}, 45{degree}, 60{degree} and 90{degree} each, so that a short-circuit current was measured for each differently inclined angle. As a result of the experiment, shown in an regression formula is a relation between the temperature conversion value of the maximum output of the solar cell at the standard temperature of 25{degree}C and the quantity of solar radiation on the inclined surface. Consequently, it enabled the prediction of a charging quantity, in the case of running a small vehicle with solar cells installed, from the quantity of solar radiation on the inclined surface in the clear weather. 2 refs., 4 figs., 2 tabs.

  8. Problems in green improvement projects in recent city planning. Kinnen no toshi keikaku ni okeru ryokuchi keikaku eno kadai

    Energy Technology Data Exchange (ETDEWEB)

    Funabiki, T. (Ministry of Construction, Tokyo (Japan))

    1992-08-06

    The present city plans are questioned on the formation of a good city environment, improvement of mansion/building supply, due to the new city problems on the Tokyo concentration and re-increase of the land value recently. Based on the discussion of the central city planning council, various improvement of the system were made by government. As a structure plan of the city, the green area plan that the balance between the urban land use and the national land use is distributed, must be included. As the problem of the green area plan on the system of city plan, this paper explained the distinguish between city area and city adjustment area, the green master plan about the green area preservation in long time, the green area system corresponded to the policy for realizing the plan of preserving the green area mainly, and the park work and green area policy corresponded to the policy for realizing the plan of creating the green area.

  9. President tunnustab Eesti riigi edendajate elutööd / Silja Joon, Ester Vilgats, Eno-Gerrit Link

    Index Scriptorium Estoniae

    Joon, Silja, 1966-

    2008-01-01

    Pärnumaalased, kes pälvivad iseseisvuspäeva puhul ja Eesti riigile osutatud teenete tunnustamiseks president Toomas Hendrik Ilveselt riiklikud autasud. Juuresolevatel fotodel Valgetähe V klassi ordeni pälvinud koorijuht ja muusikaõpetaja Toomas Voll ja Kotkaristi IV klassi teenetemärgi pälvinud Lääne prefektuuri politseiametnik Kalvi Almosen. Vt. ka lk. 1: Enn Hallik. Tatjana Jaanson üllatus suurest aust. Sõudetreener pälvib Valgetähe IV klassi teenetemärgi

  10. Application of laser cladding to the aeroengine component. Koku engine buhin eno laser nikumori yosetsu no tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Morita, A [Ishikawajima-Harima Heavy Industries, Co. Ltd., Tokyo (Japan)

    1991-08-01

    Keeping the pace with recent development and application of laser cladding, hard-facing is used more frequently on turbine blades made of superalloys used in aeroengines. This paper explains the basic principles and features of laser hard-facing technique, welding parameters, and examples of practical use. Examples of practical use include application to turbine blades used in ALF502R-5 turbo fan engines for commuter aircraft and high-pressure turbine blades used in RB211 turbo fan engines for large passenger aircraft. In the former engine, improvement of abrasion resistance was intended at the shroud section where blades are in contact with each other, for which inconel was used as the base material and CO-group alloy as the welding material. The welding used a powder supply system with a laser generator oscillating CO{sub 2} at 5 kW and employing a beam collecting mirror plus scanner to attain a beam covering wider width. Faces with higher performance were obtained than by the conventional TIG welding, and the finishing time was decreased largely. 2 refs., 9 figs., 3 tabs.

  11. Crankshaft strength and rigidity analysis and application to shape optimization; Crank jiku kyodo gosei kaisekiho to keijo saitekika eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Numajiri, S [Mitsubishi Motor Corp., Tokyo (Japan); Tamura, Y [Mitsubishi Automotive Engineering Co. Ltd., Tokyo (Japan)

    1997-10-01

    A crankshaft bending stress analysis method using an elastically supported continuous beam model has been established based on the exact evaluation of the stress concentration at fillet R sections and the crankshaft rigidity. Through various examinations, it was revealed that the calculation results of the bending stress well agreed with the actual measurements. This allowed the reliability analysis and the rigidity analysis to be used to determine optimized crankshaft specifications and web shape, which in turn made it possible to apply this method to the weight reduction of a crankshaft (material removal from web). 1 ref., 7 figs., 1 tab.

  12. Power feeding to terminal devices in optical subscriber network; Hikari fuaiba tsushin ni okeru tanmatsu kiki eno kyuden

    Energy Technology Data Exchange (ETDEWEB)

    Yamasaki, M

    1998-09-01

    This paper outlines present state of the feeding system in the light access system in consideration of backup in case of home power failure. In the optical communication, equipment with bilateral conversion function for light and electricity has to be installed both on communication service side and home side. Outline of the light access system and equipment requiring backup are shown. The following items are explained: main types of the light access system, such as FTTC (fiber to the curb), FTTP (fiber to the pole), FTTH (fiber to the home) and HFC (hybrid fiber coax), and the feeding system; problems on feeding system for the light access system. Key elements of ONU (optical network unit) for FTTH and construction of the ONU power source are illustrated. The ONU power source is composed of a backup power supply unit and main body supply unit. Backup power is indispensable to the ONU and analog telephones: output is supplied by the backup batteries in power failure. For miniaturization of the backup power source, power supply circuits and backup batteries have to be miniaturized simultaneously. History of miniaturization is explained on the experimental models. 6 refs., 7 figs., 1 tab.

  13. Role of civil technology towards environmental conservation and creation; Kankyo hozen/sozo eno doboku gijutsu no yakuwari

    Energy Technology Data Exchange (ETDEWEB)

    Kato, T. [Maeda Corp., Tokyo (Japan)

    1995-01-15

    The recent circumstances domestic and abroads around `environment` are showing a kaleidoscopic movement with the Earth Summit in 1993 as a turning point, such as the materialization of the Environmental Fundamental Law, enactment of environmental policy fundamental principle by the Ministry of Construction, and furthermore and adoption of the earth environmental action plan-agenda 21-by the Japan Society of Civil Engineers. Under the circumstances like this the civil work execution study committee has planned this panel discussion for study, for a purpose of catching hold of the environmental problem from a standpoint of the actual constructor and furthermore searching for what should be done. As a consequence, the various opinions have been presented as follows: Namely, in order to grapple with the environmental problems it is required for that a co-operation work of the civil engineers should be done with the people in the other field. As for the environmental problems, a discussion forecasted for the future is necessary. Because an environment itself is fuzzy matter, it would be better not to give the too clear solution for a concept. An attitude to make much of the matter which can not be counted is needed. The mitigation (influence alleviation countermeasure) is required for applying flexibly.

  14. Realization of an accelerator for environmental refreshment in case of soil; Fukyugata kasokuki ni yoru kankyo sosei eno koka

    Energy Technology Data Exchange (ETDEWEB)

    Isogai, H [Electrotechnical Laboratory, Tsukuba (Japan)

    1997-11-25

    Learning from a history of the earth of ancient times, the paper studies effects of refreshing environment and soil or making them natural and harmless mostly using primitive bacteria, and develops element technology which is industrially accelerating. The spread type accelerator working only by solar energy was installed and operated for experiment. As indices of refreshment effects, a study was comparatively made between a sugar degree of sweet potato and a yield shown in the number of potatotimesunit weight. An EM propagation garbage layer is formed, and the two sections were installed of a site of the actual installation of the spread type accelerator and a site naturally left alone. Other effects of weather, temperature and humidity which are external factors and general fertilization are offset as common modes, and a consideration was so made that only refreshment effects of primitive bacteria can be relatively compared. Acceleration effects in using accelerator for growing sweet potato could be quantitatively confirmed. As to sugar degree, because the last study was made in the beginning of summer, the underground temperature was high enough. Even only EM effects were fully effective. This time, the weather was much colder, and it was found to be a must to use accelerator. 2 figs.

  15. Port Artur 3 arhitektuurikonkursi võidutöö sündis Itaalias / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2006-01-01

    Pärnu kesklinna jõeäärse ala rahvusvahelise arhitektuurikonkursi tulemustest. Võitis itaalia arhitektide projekt "Flood". Teise koha võitis projekt "Istu ja vaata" (Jan Skolimovski ja Peeter Loo), kolmanda koha "Nicesaar" (Ott Kadarik, Villem Tomiste, Mihkel Tüür)

  16. Approach to load leveling in Kansai Electric Power Co. Inc.; Kansai Denryoku no fuka heijunka eno torikumi

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-09-01

    This paper presents an electric hot-water heater and ice storage air conditioning system as systems to be recommended for load leveling. Electric hot-water heater is featured by safety, cleanliness, silence and convenience because of no use of fire. Its electricity charge is only 7.15 yen/kWh less than 1/3 of that for ordinary homes because of use of midnight power. Mainly used MPU-control type electric hot-water heater is more economical because of a 15% discount system. Ice storage air conditioning system is operated in the daytime using ice made by midnight power. It is featured by reduction of facility and installation costs due to the small capacity of heat source equipment, use of inexpensive midnight power, and reduction of running cost due to small contract demand. However, since an ice storage air conditioning system is in the initial stage of diffusion, its initial cost is expensive as compared with conventional non-heat storage air conditioning systems, remaining the issue of cost reduction. 3 figs., 1 tab.

  17. Load levelling measures being tackled by shikoku Electric Power Co. Inc.; Shikoku Denryoku Kabushi Kaisha no fuka heijunka eno torikumi

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-11-01

    For the electric power companies, the activity of pushing forward the load levelling contributes greatly to the curtailment of cost by means of effective formation and utilization of facilities. It is planned to take up more positive activities with a target of 3% improvement in the load factor in ten years. Concrete measures for further promotion of load levelling are the diversity of the rate menu of appraising the load levelling effort of the customers and the promotion of the spread of equipment and systems relating to load levelling such as electric water heating apparatuses and thermal energy storage air conditioning systems. The rate system has been reviewed taking the opportunity of rate revision made in January, 1996. Particularly, further load shift to midnight time zone is expected as a result of better rate incentive for customers which is brought about by large reduction of the rate level due to the cost reduction effect accompanying the improvement in atomic power generation ratio. Outlines are given on the fields relating to general households, business, dwellings, buildings, and industry. 3 figs., 1 tab.

  18. Approach undertaken by our Company for leveling electric loads; Chubu Denryoku Kabushi Kaisha no fuka heijunka eno torikumi ni tsuite

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-07-01

    Measures for leveling the electric loads relying upon two facets - tariff system and business activities - in Chubu Electric Power Co., Inc. are presented. Firstly, the existing pricing systems for midnight electric power and electric light according to the period of time for the household as well as those of seasonal and time zone electric power, modifiable contract with the time zone and so forth for large industry users, together with a similar contract for the owner of regenerating installation are outlined. In addition, a price reduction system is indicated in favor of a scheduled shutdown of large industry operations as a means of avoiding electric consumption during weekdays in summer and between 13h and 16h when large demands exist. Further, a selective contract system put in service in 1995 and the price reduction for ice regenerating air conditioning system are cited. As for business facet, 1995 is regarded as the first year of the ice regenerator for its generalization through exhibition and promotive campaign to the foods processing industry, and the application of the latent heat regenerative system to perishable foods is recommended. Moreover, installation of energy saving type automatic vending machine, so-called eco-vendor is encouraged for its merit of peak-cut and energy price lowering. Lastly, activities to extend the use of electric calorifiers and the regenerative floor heating are mentioned. 2 figs., 1 tab.

  19. Load leveling efforts of The Hokkaido Electric Power Co. Inc.; Hokkaido Denryoku no fuka heijunka eno torikumi ni tsuite

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    The Hokkaido Electric Power Co., Inc., aiming to enhance power generation efficiency through power load levelling, strives to expand and substantiate its electricity billing menu and to popularize and encourage the use of levelling-oriented apparatuses and systems most of which are designed for utilizing midnight power. The billing menu has in it a snow-melting power which is cut off for load levelling during the peak demand time zone. For domestic use, a time zone-specified lighting system named Dream Eight is created, which is one of the billing systems dependent upon time zone. Introduced therein for industrial use is a demand/supply adjustment contract system. Furthermore, in compliance with the amended Electricity Business Law that came into force in 1995, efforts are under way for revising the period wherein power is to be supplied for melting snow, expanding the scope of application of the power supply system dependent upon time zone, and newly introducing a heat accumulation assisted peak adjustment contract system and an operation adjustment contract system. As for business efforts in relation to load levelling, the company proposes household electrical systems centering about 200V high-efficiency apparatuses, electric water warmer contributing to the enhancement of year-round load levelling, popularization and reinforcement of electric snow melting systems, and power utilizing technologies capable of meeting local demands raised for example by agriculture and fishery.

  20. Investigation of load leveling in Hokuriku Electric Power Co., Inc.; Hokuriku denryoku no fuka heijunka eno torikumi

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-08-01

    Hokuriku Electric Power Co., Inc. aims at an around 2% improvement of the load factor up to 2005, by which the quick and proper service and the proposal of load leveling menu are planned. This paper describes an outline of the investigation of load leveling. Various programs have been proposed so that the customers can further shift the load by their consideration. Proposed systems include the time-of-day electricity rate system, the load regulation contract system for industries, the seasonal time-of-day rate system, the electric power system for snowmelt in which the load is dumped at the peak, and the secondary electric power system for snowmelt. Accompanying with the revision of electric utility law, the enlargement of its available time, the price reduction, and the discount rate system for the ice regenerative air conditioners have been provided. For the business activities, a demonstration model house was exhibited to indicate a proper house with local characteristics in Hokuriku district. Furthermore, the spreading activities of regenerative systems and the consulting activities have been positively promoted. 4 figs., 1 tab.

  1. Efforts of load leveling in Tohoku Electric Power Co. Inc.; Tohoku denryoku no fuka heijunka eno torikumi ni tsuite

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-05-01

    This paper describes efforts of load leveling in Tohoku Electric Power Co., Inc. from the viewpoint of the rate system and business development. For the approach from the rate system, various rate menus for the peak shift have been arranged for domestic and large industry customers. To create the midnight demand, spread and expansion of electric hot water service are promoted. Consequently, the contract of midnight power has reached 914,000 kW at the end of 1995, which was 774,000 kW in 1985. To spread the ice regenerative air conditioning systems, the grant of incentive to the manufacturers and special discount of electricity rate have been conducted. These systems have been introduced in the eight places of Tohoku Electric Power`s business. The spread incident system has been created to introduce the automatic vending machines for beverages with the power peak cut function. Unused energy, such as exhaust heat from the non-treated sewage water and substations has been utilized as a heat supply project for city redevelopment. Multi-functional heat pump with regenerative function has been developed. This system aims at the peak shift by combining multi-functional heat pump and electric hot water service. 2 figs., 2 tabs.

  2. Ubiad1 is an antioxidant enzyme that regulates eNOS activity by CoQ10 synthesis

    NARCIS (Netherlands)

    Mugoni, V.; Postel, R.; Catanzaro, V.; De Luca, E.; Turco, E.; Digilio, G.; Silengo, L.; Murphy, M.P.; Medana, C.; Stainier, D.Y.; Bakkers, J.; Santoro, M.M.

    2013-01-01

    Protection against oxidative damage caused by excessive reactive oxygen species (ROS) by an antioxidant network is essential for the health of tissues, especially in the cardiovascular system. Here, we identified a gene with important antioxidant features by analyzing a null allele of zebrafish

  3. Application of CO2 laser cutting machine to shipbuilding; Zosen no setsudan eno CO2 laser no tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Fujimoto, Y. [Mitsui Engineering and Shipbuilding Co. Ltd., Tokyo (Japan)

    1998-11-01

    Carbon dioxide laser has been applied to cutting works in shipbuilding. As NC cutter was obsolete, CO2 laser cutting machine with a rated output 3 kW was introduced. According to the specifications of the machinable plate, the maximum thickness is 19 mm, and effective width and length are 5.4 m and 29.1 m, respectively. As the cutting width is wide and the running distance of laser beam is long, the error of light axis is expanded only by a small error of irradiation angle, which results in the inconvenience. Stable operation was realized by improving the fixation of reflecting mirror. Right angle cutting section with a cutting curve below 0.5 mm was obtained, and cutting time was reduced by the one-line cutting by which both sections can be available with a single cutting line. For the cutting of thin plate with a thickness less than 10 mm, strain was not formed, and remedy was not required. Block strain was remarkably reduced during the assembly process. Maintenance-free operation without monitoring can be performed for a long time. This machine is operated at night and lunch time, resulting in the reduced processes. The working environment is appropriate without noise and dust. Facility cost and maintenance cost were also reduced. Lower cutting speed is a weak point, when compared with the plasma cutting machine. The present machine is not applied to aluminum plates with high surface reflectivity. 13 figs.

  4. enos a ochrana informací v mobilních telekomunikacích

    OpenAIRE

    Pacák, Pavel

    2011-01-01

    Charles University in Prague Faculty of Arts Institute of Information Studies and Librarianship Study program: Information Studies and Librarianship Field of study: Information Studies and Librarianship Pavel Pacák The transfer and protection of information in mobile telecommunications Bachelor thesis abstract The work focuses on the transfer and protection of information in mobile telecommunications. First, historical development of each technology used is introduced. Also different forms of...

  5. Ecological processes for Environmental Impact Assessment in Coastal Waters; Engan no kankyo eikyo hyoka (EIA) eno seitaigakuteki apurochi

    Energy Technology Data Exchange (ETDEWEB)

    Ishikawa, Kimitoshi. [Environmental Assessment Dept., Tokyo (Japan)

    1999-03-25

    This paper focuses on a method for estimating adverse effects on natural environment by economic development in coastal waters in Japan. In particular, the most critical relations concerning the impact on marine organisms is pointed out and discussed according to an environmental impact assessment. Relations between environmental impact assessment and marine organisms needs a quantitative ecological approach in order to succeed in sustainable development of coastal waters management. Recently, the Environment Agency of Japan pointed out the unreliability and the theme on accuracy and the staff for biology and ecology in the environmental impact study. Ecological response to environmental impact occurs in a wide spectrum of physiological and biological and biological functions. Therefore biological monitoring measures must correspond to the given time-space scale of natural mechanisms. For the evaluation of environmental impact, it is desire able to develop of experimental technics and collect biological and ecological basic data for the object. I Reconstructing the following: 1. Reconstructing a clearlistic EIA process by EIA agencies and practitioners, 2. Scorping the biological and ecological issues by EIA professionals, 3. Using the current computer technology, 4. Considering monitoring systems over scales of time and space for the ecological target and 5. Making available to public all monitoring data and reports of EIA. (author)

  6. Astronaut training plans and training facilities in Japan; Uchu hikoshi tanjo eno michi (kunren to kunren setsubi)

    Energy Technology Data Exchange (ETDEWEB)

    Harada, C. [National Space Development Agency of Japan, Tokyo (Japan)

    1999-10-05

    Introduced are the training of astronauts for duties aboard a space shuttle, training provided by NASDA (National Space Development Agency of Japan), and training facilities. The astronaut candidate training course involves space science, space medicine, ocean science, and others, in addition to flight training aboard the T-38 jet trainer, emergency procedure training, shuttle system training, weightlessness training aboard the KC-135 jet plane on a ballistic flight, and SCUBA training. After candidates are named to serve aboard the space shuttle, they are to undergo training related to the shuttle system, emergency exit, adaptation to the surroundings, and the space laboratory system. As for ISS (international space station), astronauts will have to construct the station, and to stay there for a long time operating and maintaining the station and manipulating various experimental apparatuses. The astronaut training process in Japan covers approximately four years, including candidate training, advanced training, and mission dependent training. The training facilities include a weightless environment test system, low-pressure environment adaptation training system, etc., available at NASDA's Tsukuba Space Center. (NEDO)

  7. Ilves viskas koos Bedwettersiga näppu. President Ilves kohtus õpilaste ja kaitseliitlastega / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2007-01-01

    Münchenis MTV Euroopa muusikaauhindade jagamisel Uue Euroopa Heli kategoorias lauluga "Dramatic Letter to Conscience"esikoha võitnud Pärnu pop-punkbändist Bedwetters ja president Toomas Hendrik Ilvese Pärnu Sütevaka humanitaargümnaasiumi ja Kaitseliidu Pärnumaa maleva külastusest 9. novembril

  8. Application of genetically engineered microorganisms to bioremediation and wastewater treatment. Idenshi sosa biseibutsu no kankyo joka mizushori eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Fujita, M; Ike, M [Osaka University, Osaka (Japan). Faculty of Engineering

    1993-11-10

    This paper summarizes the following techniques: a gene engineering method for bioremediation and wastewater treatment, microorganism breeding using the former method, and a monitoring technique for genetical and ecological stability of genetically engineered microorganisms. Recombination bacteria reinforced with PH genes showed higher phenol removing rate than wild strains, but presented accumulation of catechol in such a large quantity as cannot be seen in wild strains, with the complete degradation rate rather decreased. Gene recombined bacteria structured by introducing the recombined plasmid, pBH500, had high genetic stability when P.putida BH-1 is used as a host. E.coli C600 having recombined plasmid and P.putida BH were added and cultivated in activated sludge. As a result, both recombined bacteria showed rapid logarithmic decrease just after the addition, then, maintained the relatively stable population groups, and remained in the activated sludge for an extended period of time. In monitoring techniques, the colony hybridization process detected clearly the gene recombined bacteria. 9 refs., 7 figs., 1 tab.

  9. Report to the Nuclear Regulatory Commission from the staff panel on the Commission's determination of an Extraordinary Nuclear Occurrence (ENO)

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-01-01

    The Panel finds that the first criterion, pertaining to whether the accident caused a discharge of radioactive material or levels of radiation offsite as defined in 10 CFR 140.84, has not been met. It further finds that there is presently insufficient information to support any definitive finding as to whether or not the second criterion, relating to damage to persons or property offsite as defined in 10 CFR 140.85, has been met. Since the Panel has not found that both criteria have been met, it recommends that the Commission determine that the accident at Three Mile Island did not constitute an extraordinary nuclear occurrence.

  10. Design and erection of the MUSEUM BRIDGE; Bijutsu no sekai eno yume no kakehashi. MUSEUM BRIDGE no sekkei seko

    Energy Technology Data Exchange (ETDEWEB)

    Ishihara, S.; Tsunekawa, M.; Umda, A.; Kishimoto, Y.; Yotsukura, Y.; Miitsu, K.; Okada, S.; Furukawa, M. [Kawasaki Heavy Industries, Ltd., Kobe (Japan)

    1998-12-20

    MUSEUM Projects for the religious corporation of Shinji-Shumeikai, at Shigaraki, Shiga prefecture. Fundamental design was by a project team led by the world-famous architect I.M. Pei. The museum is located in a prefectural park surrounded by forests. The design concept of the bridge aimed to connect Shangri-La (museum) to the real world. In order to satisfy this purpose, a cable-stayed bridge with external tendon was adopted as an original structure style, and details such as handrails, gratings, and gloss painting taken into consideration. The authors report the characteristics of the bridge and the sequence of erection. (author)

  11. Analysis of the membrane fouling on cross-flow ultrafiltration and microfiltration of soy sauce lees; Shoyuhiireden no kurosuforo roka ni okeru fauringu no kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Furukakwa, T. [Kikkoman Corporation, Chiba (Japan); Kobayashi, H.; Kokubo, K.; Watanabe, A. [Niigata University, Niigata (Japan). Graduate School of Science and Technology

    2000-05-10

    Although since the 1980's Japanese soy sauce manufactures have developed cross-flow membrane filtration systems to recover soy sauce from its lees, the mechanisms by which the membrane fouls during filtration have not been theoretically discussed. Calculated flux declines using a theoretical equation developed for cross-flow cake filtration were compared against experimental results involving the filtration of soy sauce lees using polysulfone ultrafiltration and micro filtration membranes. Membrane fouling due to the deposition and intrusion of soy sauce lees was evaluated from the hydraulic resistances of the membrane and the cake layer. Calculated flux declines with time agree with the experimental results. Specific resistance of the cake layer which is an adjustable parameter of the equation, decreases with increasing cross-flow velocity. Hydraulic resistance exhibited by the membranes is independent of feed flow velocity. However, the resistance of the cake layers decreases with increasing cross-flow velocity. This corresponds to the steady-state flux increase. In conclusion, the main cause of fouling in the filtration of soy sauce lees is cake layer formation. By using the cake filtration model for cross-flow, the flux decline with time during the filtration is capable of being predicted. (author)

  12. Seismic refraction analysis with high accuracy based on traveltime modeling; Basu keisan wo base to shita kussekiho jishin tansa kaiseki no koseidoka

    Energy Technology Data Exchange (ETDEWEB)

    Saito, H; Hayashi, K [OYO Corp., Tokyo (Japan)

    1996-05-01

    For the purpose of enhancing the efficiency of analytical processes so that those not equipped with high skill may perform a certain level of analysis and that analysis precision may be improved, some analytical techniques based on path calculation were examined. As the result, a flow of work has become feasible, wherein an early model is constructed by use of a tomography-assisted analysis to be accomplished automatedly and the result is then converted into a layer system with the velocity and thickness to be automatically corrected for the determination of the ultimate velocity layer section. Following this flow of work, almost all the parts of the work may be accomplished automatically once the travel time curve is completed. Furthermore, the calculated travel time obtained by this method can be easily compared with the observed travel time creating an opportunity to show the high reliability of this method, for this to be accepted as a standard for evaluating the accuracy of exploration. It has also been found that this method may be applied to more complicated structures which fail to satisfy the conditions for a structure to be treated by other methods such as `Hagiwara`s method.` 3 refs., 5 figs.

  13. Flow characteristic of Hijiori HDR reservoir from circulation test in 1991; Koon tantai Hijiori jikkenjo ni okeru senbu choryuso shiken (1991 nendo) kekka to ryudo kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Shiga, T; Hyodo, M; Shinohara, N; Takasugi, S [Geothermal Energy Research and Development Co. Ltd., Tokyo (Japan)

    1996-05-01

    This paper reports one example of flow analyses on a circulation test carried out in fiscal 1991 at the Hijiori hot dry rock experimental field (Yamagata Prefecture). A fluid circulation model was proposed to simulate an HDR circulation system for a shallow reservoir (at a depth of about 1800 m) demonstrated in the circulation test by using an electric circuit network (which expresses continuity impedance in resistance and fluid storage in capacitance). Storage capacity of the reservoir was estimated by deriving time constant of the system from data of time-based change in reservoir pressure associated with transition phenomena during the circulation test. The storage capacity was estimated separately by dividing change of storage in the reservoir by change in the reservoir pressure. To derive the storage in the reservoir, a method to calculate non-recovered flows in the circulation test was utilized. The results of evaluating the reservoir capacity in the shallow reservoir using the above two independent methods were found substantially consistent. 3 refs., 6 figs., 1 tab.

  14. Analysis of the pressure response of high angle multiple (HAM) fractures intersecting a welbore; Kokeisha multi fracture (HAM) kosei ni okeru atsuryoku oto kaiseki ni tsuite

    Energy Technology Data Exchange (ETDEWEB)

    Ujo, S; Osato, K [Geothermal Energy Research and Development Co. Ltd., Tokyo (Japan); Arihara, N [Waseda University, Tokyo (Japan); Schroeder, R

    1996-05-01

    This paper reports pressure response analysis on wells piercing a high angle multi (HAM) fracture model. In this model which is defined on a three-dimensional space, a plurality of slanted fractures intersect with wells at high angles (however, intersection of fractures with each other is not considered). With respect to the pressure response analysis method using this model, the paper presents a basic differential equation on pressure drawdown and boundary conditions in the wells taking flows in the fractures pseudo-linear, as well as external boundary conditions in calculation regions (a reservoir spreads to an infinite distance, and its top and bottom are closed by non-water permeating beds). The paper also indicates that results of calculating a single vertical fracture model and a slanted fracture model by using a numerical computation program (MULFRAC) based on the above equations agree well respectively with the existing calculation results (calculations performed by Erlougher and Cinco et al). 5 refs., 6 figs.

  15. Flow characteristics of Hijiori HDR reservoir form circulation test in 1995; Koon tantai Hijiori jikkenjo ni okeru shinbu choryuso yobi junkan shiken (1995 nendo) kekka to ryudo kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Fukushima, N; Hyodo, M; Shinohara, N; Takasugi, S [Geothermal Energy Research and Development Co. Ltd., Tokyo (Japan)

    1996-05-01

    This paper reports the result of a preliminary circulation test conducted in fiscal 1995 on a deep reservoir (at a depth of about 2200 m) in the Hijiori hot dry rock experimental field. One water injection well and two production wells were drilled to constitute a circulation loop, to which the circulation test was performed to investigate the flow characteristics thereof. The result revealed the following matters: total amount of injected water of 51500 m{sup 3} resulted in a total fluid recovery rate of about 40%; as a result of well stimulation given twice during the initial stage of the water injection, the continuity impedance in the vicinity of the injection well decreased largely (however, the continuity improvement upon the second attempt was considerably inferior to that from the first attempt); and increase in the water injection amount does not necessarily lead to increase in the production amount. The paper describes additionally that it is extremely difficult to interpret non-linearity between the injection and production amounts by using a model prepared previously with a main objective to analyze the Hijiori HDR circulation system. 1 ref., 9 figs., 1 tab.

  16. Subsurface interpretation based on geophysical data set using geothermal database system `GEOBASE`; Chinetsu database system `GEOBASE` wo riyoshita Kakkonda chinetsu chiiki no chika kozo kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Osato, K; Sato, T; Miura, Y; Yamane, K [Geothermal Energy Research and Development Co. Ltd., Tokyo (Japan); Doi, N [Japan Metals and Chemicals Co. Ltd., Tokyo (Japan); Uchida, T [New Energy and Industrial Technology Development Organization, Tokyo, (Japan)

    1996-05-01

    This paper reports application of a geothermal database system (GEOBASE) to analyzing subsurface structure in the Kakkonda geothermal area. Registered into the GEOBASE to analyze specific resistance structure in this area were depth information (well track and electric logging of existing wells), three-dimensional discretization data (two-dimensional analysis cross section using the MT method and distribution of micro-earthquake epicenters), and two-dimensional discretization data (altitude, and depth to top of the Kakkonda granite). The GEOBASE is capable of three-dimensional interpolation and three-dimensional indication respectively on the three-dimensional discretization data and the depth information table. The paper presents a depth compiling plan drawing for 2000 m below sea level and an SE-NE cross section compiling cross sectional drawing. The paper also indicates that the three-dimensional interpolation function of the GEOBASE renders comparison of spatial data capable of being done freely and quickly, thereby exhibiting power in the comprehensive analysis of this kind. 3 refs., 8 figs., 2 tabs.

  17. Evaluation stationariness of triaxial seismic while drilling and detection of reflected wave; Kosei kussaku ni tomonau danseiha no sanjiku kaiseki ni yoru hiteijo hyoka to hanshaha no kenshutsu

    Energy Technology Data Exchange (ETDEWEB)

    Yoshida, T; Asanuma, H; Niitsuma, H [Tohoku University, Sendai (Japan). Faculty of Engineering

    1996-05-01

    This paper reports a method to detect reflected wave components contained in an elastic wave caused in association with well drilling. Measurement was made on an elastic wave caused in association with well drilling in an experimental field by using a triaxial elastic wave detector disposed in a measurement well. Analyzing the particle motion tracks in the derived elastic wave signals (to derive the main axial direction of a three-dimensional hologram) revealed that oscillation direction of the signals changes non-steadily by time centering around the S-wave oscillation direction. In addition, a sound source position was estimated during the drilling. Existence probability of the S-wave signal in the non-steady continuous signals was estimated by handling the particle motion tracks stochastically. In addition, this existence probability was used as a weighting function for a correlative analysis to detect a reflected wave from directly reaching wave components in the non-steady continuous signals. Thus, improvement in reliability of reflected wave detection was attempted. Effectiveness of this method was endorsed by the field data. 3 refs., 7 figs.

  18. Development of the electromagnetic tomography system. Sensitivity study of anomalous body by model studies; EM tomography system no kaihatsu. Model kaiseki ni yoru ijotai no kando chosa kekka

    Energy Technology Data Exchange (ETDEWEB)

    Kumekawa, Y; Miura, Y; Takasugi, S [Geothermal Energy Research and Development Co. Ltd., Tokyo (Japan); Arai, E [Metal Mining Agency of Japan, Tokyo (Japan)

    1996-05-01

    An examination was made by a model analysis on sensitivity and the like against a resistive anomalous body, in connection with an electromagnetic tomography system with surface earthquake sources and underground receiver arrangements. A resistivity model was of a three-dimensional structure, and built with a 5 ohm{center_dot}m low resistivity anomalous body assembled in a 100 ohm{center_dot}m homogeneous medium. As a result of the examination, it was shown that the size limitation of an analyzable anomalous body was 50{times}50{times}20m at a frequency of 8 to 10kHz and that a system with high precision in a high frequency range was necessary. The examination of effects under a shallow anomalous body revealed, for example, that the fluctuation of a low frequency response was large compared with a deep anomalous body and that, where a second anomalous body existed under it, the effect also appeared with a surface earthquake source positioned in the opposite side from the anomalous body. The examination of effects under the three dimensional structure revealed, for example, that a remarkable change appeared in the data with the change in the inclined angle of the transmission line against the strike of the anomalous body. 4 refs., 7 figs.

  19. Development of multi-frequency array induction logging (MAIL) tool. 3; Multi shuhasu array gata induction kenso tool (MAIL) no kaihatsu (genchi shiken data no ichijigen kaiseki). 3

    Energy Technology Data Exchange (ETDEWEB)

    Sato, T; Osato, K; Takasugi, S [Geothermal Energy Research and Development Co. Ltd., Tokyo (Japan); Uchida, T [New Energy and Industrial Technology Development Organization, Tokyo, (Japan)

    1996-05-01

    A field test was carried out in 1995 on a deep-seated geothermal investigation and reduction well WDR (in Kakkonda, Shizuku-ishi, Iwate Prefecture) by utilizing a multi-frequency array induction logging tool which is under development by NEDO. This paper reports results of analyzing the acquired data. With the WDR wells, an investigation has been conducted to a drilling depth of 330 m. Three frequencies in a range from 3 to 24 kHz provided relatively good data, but data with 42 kHz had poor quality that cannot be utilized for the analysis. Precise device calibration is difficult on data acquired from three array type vertical component magnetometers (the difficulty may be due to a signal line from a transmitter passing on the magnetometer side). Because of this difficulty, analysis using one-dimensional inversion program was performed by using ratio of the amplitude for each frequency and phase difference as input data. The analysis allowed to have derived a result that corresponds to the ground bed structure. 5 refs., 8 figs., 3 tabs.

  20. Analysis of output characteristics of PV modules under natural sunlight; Shizen taiyokoka ni okeru taiyo denchi module shutsuryoku tokusei no kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Murai, Y.; Igari, S. [Japan Quality Assurance of Organization, Tokyo (Japan)

    1997-11-25

    The paper measured current/voltage characteristics of various PV modules under natural light and analyzed various characteristics such as generated output and module power generation efficiency. In the experiment, installing various PV modules at the solar techno center located at north latitude 34.7deg and east longitude 137.6deg, measurement was made by I-V curve tracer, pyranometer, and thermocouple buried on the module back. As a result, the following were confirmed: As to the monthly mean power generation efficiency, the crystalline system is lowest in summer and highest in winter, and the amorphous system highest in summer and lowest in winter. Concerning the power generation efficiency and illuminance, the gap of power generation efficiency between at high illuminance and at low illuminance is large in the crystalline system and small in amorphous system. Relating to the azimuth angle of module installation and the generated output, the installation inclined 15deg angle west in summer and 15deg angle east in fall/winter generates more power in the crystalline system. On the contrary, the installation on the south face generates more power in the amorphous system. 4 refs., 8 figs., 3 tabs.

  1. Numerical response analysis of a large mat-type floating structure in regular waves; Matogata choogata futai kozobutsu no haro oto kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Yasuzawa, Y.; Kagawa, K.; Kitabayashi, K. [Kyushu University, Fukuoka (Japan); Kawano, D. [Mitsubishi Heavy Industries, Ltd., Tokyo (Japan)

    1997-08-01

    The theory and formulation for the numerical response analysis of a large floating structure in regular waves were given. This paper also reports the comparison between the experiment in the Shipping Research Institute in the Minitry of Transport and the result calculated using numerical analytic codes in this study. The effect of the bending rigidity of a floating structure and the wave direction on the dynamic response of a structure was examined by numerical calculation. When the ratio of structure length and incident wavelength (L/{lambda}) is lower, the response amplitude on the transmission side becomes higher in a wave-based response. The hydrodynamic elasticity exerts a dominant influence when L/{lambda} becomes higher. For incident oblique waves, the maximum response does not necessarily appear on the incidence side. Moreover, the response distribution is also complicated. For example, the portion where any flexible amplitude hardly appears exists. A long structure response can be predicted from a short structure response to some degree. They differ in response properties when the ridigity based on the similarity rule largely differs, irrespective of the same L/{lambda}. For higher L/{lambda}, the wave response can be easily predicted when the diffrection force is replaced by the concentrated exciting force on the incidence side. 13 refs., 14 figs., 3 tabs.

  2. Theoretical study on composition of gas produced by coal gasification; Sekitan gas ka de seiseisuru gas no sosei ni kansuru kosatsu (HYCOL data no doteki kaiseki)

    Energy Technology Data Exchange (ETDEWEB)

    Kaiho, M.; Yasuda, H.; Kobayashi, M.; Yamada, O.; Soneda, Y.; Makino, M. [National Institute for Resources and Environment, Tsukuba (Japan)

    1996-10-28

    In relation to considerations on composition of gas produced by coal gasification, the HYCOL hydrogen generation process data were analyzed. From the fact that CO concentration (Y) decreases linearly with CO2 concentration (X), element balance of gasification of reacted coal was used to introduce a reaction analysis equation. The equation includes a term of oxygen excess {Delta}(amount of oxygen consumed for combustion of CO and H2 in excess of the theoretical amount), derived by subtracting the stoichiometric oxygen amount used to gasify coal into CO and H2 from the consumed oxygen amount. The {Delta} can be used as a reference to oxygen utilization efficiency. An equation for the {Delta} was introduced. Also introduced was a term for steam decomposition amount derived by subtracting the generated steam from the supplied steam. These terms may be used as a clue to permeate into the gasifying reaction process. This suggestion was discussed by applying the terms to gas composition value during operation. According to the HYCOL analysis, when a gasification furnace is operated at higher than the reference oxygen amount, coal supply variation is directly reflected to the combustion reaction, making the {Delta} distribution larger. In an inverse case, unreacted carbon remains in the furnace due to oxygen shortage, and shift reaction may occur more easily even if oxygen/coal supply ratio varies. 6 figs., 1 ref.

  3. Analysis of combustion in an ATAC engine with measurement of radical luminescence; Radical hakko keisoku ni yoru ATAC engine no nensho kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Park, Y; Oguma, H; Ueda, H; Iida, N [Keio University, Tokyo (Japan)

    1997-10-01

    In order to make clear of the combustion mechanism and the frame structure in two stake, so called, active thermo-atmosphere combustion (ATAC) engine fueled by gasoline and methanol, we measured the 2-demensional images of OH, CH and C2 radical band spectra in both ATAC and SI combustion mode. From the results of pressure data in the cylinder, the heat release rate was calculated. We evaluated the correlation of radical luminescence intensity and the rate of heat release. 3 refs., 4 figs., 2 tabs.

  4. Optimum stamping die structure based on analytical method of die deformation during draw process; Seikei katei no kanagata henkei kaiseki ni motozuku, press kanagata kozo no saitekika

    Energy Technology Data Exchange (ETDEWEB)

    Nakahara, T; Tamai, H [Mazda Motor Corp., Hiroshima (Japan)

    1997-10-01

    We measured an actual deformation and pressure distribution in draw process of bending cam, and analyzed deformation process of die structure, in order to eliminate adjusting work considering die deformation by stamping force. We studied die structure improvement with simulation based on analytical method. This report describes a sample of die structure improvement based on a simulation and actual measurement. 1 ref., 11 figs., 1 tab.

  5. Fundamental study on an analytical system of 1/f fluctuation considered a matrix of colours; Iro hairetsu wo koryoshita 1/f yuragi kaiseki system no kisoteki kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    Kitayama, Y. [Hiroshima Institute of Technology, Hiroshima (Japan); Takagi, T. [Hiroshima Shudo University, Hiroshima (Japan); Nakashima, Y. [Nippon Telegraph and Telephone Corp., Tokyo (Japan)

    1998-03-31

    The impression which an illustrations in newspaper advertisements and wrapping paper give to human beings plays an important role in commodity sales. When we try to evaluate the comfort level which these illustrations give to human beings, 1/f fluctuation caused by the colour array can be considered as one important element. As a fundamental study of the method to evaluate such illustrations from the standpoint of a colour array, we have studied a method that measures the comfort level of round shaped four colours with conformity arranged on plain white paper. This system presupposes that the four colours exert a mutual influence of potential energy according to their arrangement. We have tried to define and evaluate this energy. The comfort level is measured using the calculation value of energy. For this study, we have used the above proposed system to compare 16 kinds of samples conforming to the above method calculating the value of energy with the results of a questionnaire answered by two or more groups of human beings. 9 refs., 6 figs., 1 tab.

  6. Surge analysis of the MAGLEV coil for propulsion and guidance; Jiki fujoshiki tetsudo ni okeru suitei annaiyo coil no surge kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Ema, S [Numazu College of Technology, Shizuoka (Japan)

    1995-11-20

    The MAGLEV (magnetically levitated train) is now well along in development testing in Japan. MAGLEV is unlike conventional railways, so various problems lie in the technology of MAGLEV. One of them is surge analysis of the MAGLEV coil for propulsion and guidance (`coil for propulsion` for short). The coil for propulsion is installed on each side of the outdoor guideway. Thus, the power system of MAGLEV is always exposed to lightning and circuit switching. Accordingly, it is very important to do a rational insulation plan to prevent damage when surges enter the coils. In view of this situation I performed experiments using the mini model coils and clarified impulse voltage distribution at the end of each coil and simulated the surge characteristics by giving the inverted L equivalent circuit to the coil for propulsion. As a result, the measured values and calculated values were almost equal in the surge characteristics. Further, the surge characteristics of the Miyazaki test track and the future MAGLEV were examined. 10 refs., 17 figs., 1 tab.

  7. Characteristic analysis of turbulent heat diffusion in a multi-compartment structure; Takukakuka kukan kozo ni okeru ranryunetsu kakusan gensho no kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Hu, C; Fukuchi, N [Kyushu University, Fukuoka (Japan). Faculty of Engineering

    1997-10-01

    An analysis was made on turbulent heat diffusion in a multi-compartment structure necessary for designing calorific power and environment for functional systems used in marine vessels and off-shore structures. In a multi-compartment structure, the diffusion phenomenon is complex because of movement of air flow in turbulence and buoyancy resulted from non-isothermal condition. The phenomenon is largely affected by space shapes and walls, and the conditions in heat diffusion field is governed also by shapes of opening connecting the compartments. An analysis was made by using the SIMPLE method on turbulent heat diffusion in a multi-compartment space with high Raleigh number in which natural convection is dominant. If the opening is small, the Coanda effect appears, in which air flow passing through the opening rises along the wall, wherein a high-temperature layer is formed near the ceiling, making the heat diffusion inactive. If the opening is large, a jetting flow from the opening and a large circulating flow are created, which cause active advection mixture, making temperature gradient smaller in the upper layer. Heat transfer intensity in an opening on a partition wall decays in proportion with 1/4th power of the opening ratio. 7 refs., 11 figs.

  8. Analysis of crashes using FE vehicle models. Relations between vehicle types and crash characteristics; Yugen yoso model wo mochiita sharyo no shototsu kaiseki. Sharyo type to shototsu tokusei

    Energy Technology Data Exchange (ETDEWEB)

    Takatori, O. [Japan Automobile Research Institute Inc., Tsukuba (Japan)

    2000-01-01

    The objective of this study is to analyze the crash characteristics of vehicles under the condition of real-world accidents. This paper pays attention to the differences in the crash characteristics of a vehicle colliding with a vehicle which is a different type. Vehicles on the market can be divided broadly into two vehicle structures, monocoque structure and frame structure. Monocoque structure is mainly used for passenger vehicles and frame structure is for recreational vehicles (RV). In recent years, RV has been a large seller on the market. So accidents between passenger vehicles and a RVs occur frequently. The analysis of experimental data and computer simulation, which is predicated on the experimental data, was carried out for this study. In the analysis of experimental data, barrier force data from the New Car Assessment Program (NCAP) were analyzed. The FE passenger vehicle model which is based on systematic validation tests was used for the computer simulation of car-to-car collisions. (author)

  9. Controlled levitation of Y-Ba-Cu-O bulk superconductors and energy minimum analysis; Y-Ba-Cu-O baruku chodendotai no fujo to enerugi kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Magashima, K. [Railway Technical Research Institute, Tokyo (Japan); Iwasa, Y. [Francis Bitter Magnet Laboratory, Canbridge (United States); Sawa, K. [keio University, Tokyo (Japan); Murakami, M. [Superconductivity research Laboratory, Tokyo (Japan)

    1999-11-25

    The levitation of bulk Y-Ba-Cu-O superconductors can be controlled using a Bi-Sr-Ca-Cu-O (Bi2223) superconducting electromagnet. It was found that stable levitation without tilting could be obtained only when the sample trapped a certain amount of fields, the minimum of which depended on the external field and sample dimensions. We employed a novel analysis method for levitation based on the total energy balance, which is much simpler than the force method and could be applied to understanding general levitation behavior. Numerical analyses thus developed showed that stable levitation of superconductors with large dimensions cen only be achieved when the induced currents can flow with three-dimensional freedom. (author)

  10. Velocity profiles of acoustic streaming in resulting stokes layer by acoustic standing wave in a duct; Kannai kichi shindo ni okeru stokes sonai onkyoryu ryusoku bunpu no kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Arakawa, M; Kawahashi, M [Saitama University, Saitama (Japan). Faculty of Engineering

    1995-07-25

    Acoustic streaming is generated by Reynolds stress in the sense of mean acoustic momentum flux in a sound field. In the case of an acoustic standing wave produced by an air column oscillation in a closed duct, the friction and the Reynolds stress in the resulting Stokes layer are the essentials of acoustic streaming generation in the vicinity of the duct wall. The thickness of the Stokes layer decreases with the oscillatory Reynolds number. The plane wave propagation in the duct is assumed for the case of high Reynolds number except for the thin Stokes layer adjacent to the duct wall. The velocity profiles of the streaming are estimated theoretically from the steady component of the second-order term of a perturbation expansion in which the first-order approximation is a sinusoidal oscillation of the air column with plane waves. The present paper describes theoretical analysis of the velocity profiles of the acoustic streaming in the Stokes layer by means of the matched asymptotic expansion method. The results obtained show the existence of reverse streaming in a very thin layer adjacent to the wall and the effects of thermal boundary conditions at the wall on the velocity profiles of acoustic streaming in the Stokes layer. 9 refs., 8 figs.

  11. Review of an analysis system of `Long-Term Deep Seafloor Observatory off Muroto Peninsula`; Kochiken Murotomisakioki `kaitei jishin sogo kansoku system` data no kaiseki system no shokai

    Energy Technology Data Exchange (ETDEWEB)

    Tsuru, T; Machiyama, H; Hattori, M; Kaneda, Y [Japan Marine Science and Technology Center, Kanagawa (Japan)

    1997-10-22

    Introduced is a data analysis system for Long-Term Deep Seafloor Observatory established off Muroto Point by Japan Marine Science and Technology Center (JAMSTEC), from which observatory data collected by seismograph and tsunami-meter are transmitted real time. JAMSTEC Long-Term Deep Seafloor Observatory Project Team has begun constructing an analysis system for disposing of events in the data and for locating the hypocenter. The analysis system is composed of a data converting unit that converts the forwarded data into the Win format; a data storage/time-dependent data integration unit that keeps the data in a hard disk for a specified period of time, performs disposition and analysis of events in the data, and forwards the data after disposition and analysis to a data recording unit; a data recording unit that stores selected data of seismic events in a recording medium; and a real-time monitor/NTP server unit that displays real time the observed seismic waveform data. 2 figs.

  12. Remote sensing data analysis for assessment of sea level change in Asia; Asia ni okeru kaisuijun hendo eikyo hyoka no tame no remote sensing gazo kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Okubo, Y; Tanaka, A [Geological Survey of Japan, Tsukuba (Japan); Kaku, M [Bishimetal Exploration Co. Ltd., Tokyo (Japan)

    1997-10-22

    Remote sensing images include information of coastal land division, sea level change such as sedimentary environment and vegetation, and distribution of artificial structures. Past sea level changes and their causes can be regionally obtained by analyzing these data and by integrating them with information obtained from geological survey. In this study, causes and history of past sea level changes, formation mechanism of coastal topography, and past sea level change survey in Thailand have been reviewed. This paper describes an extraction method of the sea level change information in coastal districts by analyzing several actual remote sensing images. For understanding the current sea level rise, it is required to clarify the causes quantitatively among three causes of sea level changes, i.e., volumetric change of total ocean water on the earth, relative sea level change due to the crustal deformation, and change of irregularity of sea surface with ocean current. It is also required to compile maps in Asian or global scales. 13 refs., 6 figs.

  13. Ac system interruption analysis of an orthogonal-core type dc-ac converter. Koryu keito shadanji no chokko jishinkei dc-ac renkeiyo henkanki no dosa kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Sato, K; Ichinokura, O; Jinzenji, T [Tohoku Univ., Sendai (Japan). Faculty of Engineering; Tajima, K [Akita University, Akita (Japan). Mining College

    1991-04-30

    This paper reports on a numerical analysis of transient response of an orthogonal-core type dc-ac converter that takes place when the external ac system connected is cut off from it. A model of magnetic circuit of the orthogonal core is presented, which has magnetic inductances to represent effects produced by hysteresis that are connected in series with magnetic reluctances, thereby making it possible to divide each of primary and secondary winding current into magnetization current associated with magnetic reluctances and iron-loss current due to hysteresis. Moreover, a numerical model of the orthogonal core is derived from expressions for non-linear characteristics of these reluctances and inductances to make use of it for analyses employing the circuit simulator SPICE. Transient response of the present converter, namely time variation of both voltage and current in its every part, to the sudden change in condition that is caused by switching off the ac system connected to its secondary side is calculated, while applying square-wave voltage to its primary side. It is noted that calculated wave forms of both secondary winding current and open-circuit voltage are fairly in good agreement with those obtained by an experiment performed on the same condition. 4 refs., 9 figs., 1 tab.

  14. Study on the behavior of reaction disk in the vacuum brake booster; Shinkushiki bairyoku sochi ni okeru reaction disk no kyodo kaiseki jikken

    Energy Technology Data Exchange (ETDEWEB)

    Kuroda, M; Sawada, T; Kato, Y [Tokyo Univ. of Agriculture and Technology, Tokyo (Japan); Ogawa, E; Nakamura, S [Jidosha Kiki Co. Ltd., Tokyo (Japan)

    1997-10-01

    Vacuum brake booster has been widely applied in automobiles, and it needs much time for experiments in order to design a new type model and so on. In this report concentrating on the behavior of a reaction disc, it was simulated by ARAQUS FEM program where coefficients of rubber disc are Mooney-Rivlin constants. It was shown that the numerical results represent good agreement with experiments, and in addition that values of jumping force which shows the starting point of the brake increases with the increment of the hardness of the disc, clearance and so on. 2 refs., 10 figs.

  15. Analysis of combustion behavior in DI diesel engine at low temperature; DI diesel engine ni okeru teionji no nensho kyodo kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Kuzuya, Y; Shibata, H [Nippon Soken, Inc., Tokyo (Japan); Aoki, S; Itatsu, T [Toyota Motor Corp., Aichi (Japan)

    1997-10-01

    For NOx reduction of a DI diesel engine, the retard of fuel injection timing is effective. However, it causes the white smoke at low temperature and low load. To analyze the mechanism of white smoke generation, a new visualizing system of fuel spray and flame behavior has been developed. This system can be also applied to a 4-valves per cylinder production engine by integrating two optical systems for image and lighting. From the visualization of the fuel spray and the flame behavior in the combustion chamber at low temperature, it has been proved that prompt fuel evaporation before reaching the wall surface of combustion chamber is required to reduce the white smoke. 6 refs., 10 figs., 3 tabs.

  16. Automobile simulation model and its identification. Behavior measuring by image processing; Jidosha simulation model to dotei jikken. Gazo kaiseki ni yoru undo no keisoku

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, H; Morita, S; Matsuura, Y [Osaka Sangyo University, Osaka (Japan)

    1997-10-01

    Model simulation technology is important for automobiles development. Especially, for the investigations concerning to ABS, TRC, VDC, and so on, the model should be the one which can simulates not only whole behaviors of the automobile, but also such internal information as torque, acceleration, and, velocity of each drive shafts, etc.. From this point of view, 4-wheels simulation model which can simulates almost over 50 items, was made. On the other hand, technique of 3-D image processing using 2 video cameras was adopted to identify the model. Considerably good coincidences were recognized between the simulated values and measured ones. 3 refs., 7 figs., 2 tabs.

  17. Identification of Fusarium oxysporum in the fluid of hydroponic culture using DNA analysis; DNA kaiseki ni yoru suiko saibai yoekichu no horenso ichobyokin

    Energy Technology Data Exchange (ETDEWEB)

    Oyama, K.; Kawabata, T. [Chugoku Electric Power Co. Inc., Hiroshima (Japan)

    1999-09-24

    In the case of circularly using a fluid of the hydroponic culture for crops such as vegetable, the destructive damage is caused when specified harmful germs multiply in the growing crop. therefore, it is necessary to find the germs in question out and deal with them as quickly as possible. In this paper, studies were made on a sure identification technology of F. oxysporum using DNA analysis and the measures to prevent crop damages caused by diseases. The results of the study are reported. (translated by NEDO)

  18. Fundamental analysis of thermally regenerative fuel cell utilizing solar heat; Taiyonetsu wo riyosuru netsu saiseigata nenryo denchi no kiso tokusei no kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Ando, Y; Tanaka, T; Takashima, T; Doi, T [Electrotechnical Laboratory, Tsukuba (Japan); Aosawa, T; Kogoshi, S [Science University of Tokyo, Tokyo (Japan)

    1997-11-25

    Study was made on a thermally regenerative fuel cell using solar heat. The thermally regenerative fuel cell was devised which is composed of 2-propanol liquid-phase endothermic dehydrogenation at nearly 100degC, and acetone liquid- phase exothermic hydrogenation at nearly 30degC as reverse reaction. This low-temperature dehydrogenation can relatively easily utilize a flat solar heat concentrator. 2-propanol dehydrogenation generates acetone and hydrogen. Generated acetone generates electric power in hydrogenation, generating propanol. This propanol regenerates acetone and hydrogen in dehydrogenation. The activity of Ru and Pt composite catalyst was considerably higher than that of Ru or Pt single catalyst. The activity was also higher in carbon felt or carbon cloth carrier than carbon plate carrier. The open circuit voltage of the fuel cell was estimated to be 110-120mV, nearly consisting with theoretical values. Short circuit current was also estimated to be 9-11mA, suggesting reduction of its internal resistance as an important subject. 4 refs., 5 figs., 2 tabs.

  19. Character of photovoltaic/thermal hybrid collector. Character analysis by numerical calculation; Taiyoko netsu hybrid collector no tokusei. Suchi keisan ni yoru tokusei kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Morita, Y; Iwawaki, T; Fujisawa, T; Tani, T [Science University of Tokyo, Tokyo (Japan)

    1997-11-25

    In order to investigate characteristics of photovoltaic (PV)/thermal hybrid collectors (PV/T{sub s}) operating under varying conditions, energy equilibrium equations have been developed for numerical calculation, and the calculated results were compared with the observed ones. The calculated characteristics are close to the observed ones, both for photoelectric conversion and heat collecting characteristics, demonstrating validity of these energy equations. It is found, by comparing characteristics of PV/T{sub A} (covered with glass) with those of PV/T{sub B} (not covered with glass), that these characteristics are greatly affected by glass cover. Maximum overall excergy levels attained are 13.29% with PV/T{sub A} and 11.48% with PV/T{sub B} under the conditions of solar radiation intensity H: 800W/m{sup 2}, ambient temperature: 20degC and wind velocity: 0.5m/s, where flow rates of heat medium are 2.0times10{sup -3} and 4.0times10{sup -3}kg/s, respectively. Thus, the PV/T{sub A} system has a higher maximum excergy efficiency than the PV/T{sub B} system. The PV/T{sub A} gives water of higher temperature, demonstrating that covering the system with glass increases maximum excergy efficiency and optimum temperature. 6 refs., 5 figs., 2 tabs.

  20. Seismic tomography analysis using finite differential calculation of the eikonal equation and reciplocal principle; Eikonal equation no sabunkaiho to sohan genri wo riyoshita danseiha tomography kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Fujimoto, M; Ashida, Y; Watanabe, T; Sassa, K [Kyoto University, Kyoto (Japan)

    1996-10-01

    This paper describes the seismic tomography analysis of underground structures using finite differential calculation (FDC) and a reciprocal principle which points out that a propagation path is constant even if a source and receiver are exchanged with each other. Tomography analysis generally determines a ray length across each underground cell structure by ray tracing method to modify each cell slowness (inverse of velocity). Travel time field was determined by FDC of eikonal equation among ray tracing methods, and a wave propagation path was determined by reciprocity of elastic wave to carry out inversion. In conventional methods, since a wave length is assumed to be infinitesimal by ray theory, false modified slowness structures frequently appears depending on the density of a ray. Wave propagates in a certain width, and is affected by environment. The slowness was thus modified on the basis of the wave propagation path with a certain width by using not ray-tracing but reciprocity. By this modification, false structures were hardly found under a fine grid, and several propagation paths could be considered. 6 refs., 9 figs.

  1. Subsurface interpretation based on geophysical data set using geothermal database system `GEOBASE`. 2; Chinetsu database system `GEOBASE` wo riyoshita Kakkonda chinetsu chiiki no chika kozo kaiseki. 2

    Energy Technology Data Exchange (ETDEWEB)

    Osato, K; Sato, T; Miura, Y; Yamane, K [GERD Geothermal Energy Research and Development Co. Ltd., Tokyo (Japan); Doi, N [Japan Metals and Chemicals Co. Ltd., Tokyo (Japan); Uchida, T [New Energy and Industrial Technology Development Organization, Tokyo, (Japan)

    1997-05-27

    Five cross sections were applied as a result of MT method investigations in addition to the results of conventional analyses at the Kakkonda geothermal area; three-dimensional resistivity distribution was made into a database by using the Kriging method which makes a matching with anisotropy of seismic center distribution in micro-earthquakes; and the database was compared with the data derived from surveys on the pilot survey well WD-1a and the side-truck well WD-1b thereof. As a result, it was found that the well WD 1b which encountered a water loss zone had the water loss zone exist in a region with relatively lower resistivity than in the well WD-1a which did not encounter a water loss zone. The region in which the water loss zone was encountered existed in a very steep slope region going from the high resistivity region in the west side toward the low resistivity region in the east side. This fact suggests a possibility that fractures have developed in this region with sharp slope in the resistivity in this area. Adding three-dimensional complementary function to the GEOBASE database by using a simple Kriging allowed the direction of anisotropy in spatial data to be freely and quickly decided. It was learned that this capability exhibits strong power in a mapping work in structures where such anisotropy as a geothermal zone is highly dominant. 5 refs., 8 figs., 2 tabs.

  2. X-ray diffraction analysis and MO calculations of 1H-tetrazole; 1H-tetorazoru no Xsen kessho kozo kaiseki to bunshi kido keisan

    Energy Technology Data Exchange (ETDEWEB)

    Ono, Yoshio.; Akutsu, Yoshiaki.; Arai, Mitsuru.; Tamura, Masamitsu. [The University of Tokyo, Tokyo (Japan). School of Engineering; Matsunaga, Takehiro. [National Institute of Materials and Chemical Research, Tsukuba (Japan)

    1999-02-28

    The X-ray diffraction analysis and the MO calculations of 1H-tetrazole were carried out, in order to explain its high stability. From the X-ray diffraction analysis, five bonds in the ring have intermediate lengths between single and double bond lengths. Therefore, 1H-tetrazole is quite stable because of its aromaticity. The N1-C5 distance of 1.315A is significantly short. The molecular structure which was calculated by the ab initio MO calculation of one 1H-tetrazole molecule at MP2/6-31G* level, showed a good agreement with our experimental one, except for the abnormal short N1-C5 distance. From the calculations of dimers and trimers, 1H-tetrazole is shown to be stabilized by a strong intermolecular electrostatic interaction between the protons and the delocalized electrons over the ring. (author)

  3. Nodal head method with matric operation in analysis of mine ventilation networks. Matrics kaiho wo mochiita setten ho ni yoru tsuki mo kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Sasaki, K.; Miyakoshi, H. (Akita Univ., Akita (Japan). Mining College); Kinoshita, H.; Onozuka, T. (Hanaoka Mining Co. Ltd., Akita (Japan))

    1990-09-25

    In this report, the method of analyzing mine ventilation networks is explained in which the direct matric operation method is applied to the solution of the linear equation system introduced from the fundamental equation of the nodal head method. In other words, the fundamental equation was expressed by genelarized equation composition by using connecting functions between nodes and the algorism of a computer program was clarified. And the calculation method necessary for other ventilation netwrks analysis was shown in a concrete form. For solving the linear equation system, the matric operation method based on the modified Choleski's method was used in order to speed up the calculation and stabilize the convergence process of the solution. As examples, calculation was made on the ventilation networks of total numbers of the nodes of 8, 14, 51 and 141. From these ventilation network analyses, using a linear equation system concerning the nodal pressure correction, it was found that in the system with convergence acceleration coefficient of 1.4, the number of sequential repeating frequency of approximation Mc which was required for convergence was in the order of Mc {approx equal} 13 (cycle) for the condition that the fan pressure was constant and the convergence condition was {vert bar} AQi {vert bar}{sub max} {lt} 0.1m {sup 3}/min. 14 refs., 12 figs., 3 tabs.

  4. Fiscal 2000 report on result of the full-length cDNA structure analysis; 2000 nendo kanzen cho cDNA kozo kaiseki seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    This paper explains the results of research on full-length cDNA structure analysis for the period from April, 2000 to March, 2001. The outline of human genome sequence was published in June, 2000. In Japan, human gene analysis was such that, as the basic technology of the bio industry, a millennium project was decided in the budget of fiscal 2000. The full-length cDNA structure analysis is the core of the project. The libraries of cDNA were prepared using full-length and more than 4-5kbp-long cDNAs by oligo-capping method. It began from determining partial sequence data at end cDNA, and then, with new clones selected therefrom, full-length human cDNA sequence data were determined. The partial sequence data determined by fiscal 2000 were 1,035,000 clones while the full-length sequence data were 12,144 clones. The sequence data obtained were analyzed by homology search and translated into amino acid coding sequences, with predictions conducted on protein functions. A clustering method was examined that selects new clones from partial sequences. Database was constructed on gene expression profiles and disease-related gene sequence data. (NEDO)

  5. Buckling collapse analysis of framed structures by using adaptively shifted integration technique. Junnogata shifted intergration ho ni yoru honegumi kozo no zakutsu hokai kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Toi, Y.; Isobe, D. (The University of Tokyo, Tokyo (Japan). Institute of Industrial Science)

    1993-09-01

    This paper describes the following matters on application of an adaptively shifted integration technique to a buckling collapse analysis of framed structures: This method is a method in a finite element analysis using three-dimensional girder elements to arrange value integration points at optimal locations in a linear analysis if the elements are in an elastic transform condition on the whole. The method then moves the value integration points so that plastic hinge will occur in these locations immediately after part of the elements has yielded. The method was applied to analyzing an elastic buckling problem in several loading patterns for either a both-end supported or a one-end fixed beam member. A result was obtained that a number of elements required for one member is four at minimum. In a buckling analysis of framed structures, a satisfactory result was obtained by using an automatic element segmenting algorithm, which begins the analysis with one element one member, and immediately after a member is determined with a possibility of generation of buckling, splits that member only into four elements. 6 refs., 5 figs.

  6. Improvement of D.I. diesel engine combustion using numerical simulation; Chokufun diesel kikan no nensho kaizen shuho. Suchi kaiseki ni yoru torikumi

    Energy Technology Data Exchange (ETDEWEB)

    Minami, T.; Adachi, T.; Isyii, Y. [Isuzu Motors Ltd., Tokyo (Japan)

    1999-04-01

    For the purpose of improving DI diesel engine combustion, it is important to predict air flow of intake and exhaust manifold, intake port flow, combustion chamber swirl and fuel spray combustion. This paper describes the application of numerical simulation to the engines, the analysis of phenomena and a problem of simulation model modification. (author)

  7. Improvement of image velocimetry based on a spatio-temporal correlation method; Jikukan sokan ni motozuku ryushi gazo sokudoba keisokuho no kaiseki seino kaizen

    Energy Technology Data Exchange (ETDEWEB)

    Yamada, H. [Tokuyama College of Technology, Yamaguchi (Japan); Arifuku, T. [Komatsu Ltd., Tokyo (Japan); Koga, K. [Yamaguchi University, Yamaguchi (Japan). Faculty of Engineering

    1998-05-31

    In the image velocimetry, it is generally required to detect the various velocity in each position of the flow field. But the maximum velocity which the usual velocimetry can detect has been limited in about 1 pixel per frame. Then, in order to measure the wide range of velocity vectors from the dynamic image, the improvement of performance in the image velocimetry based on a spatio-temporal correlation method would be attempted by enlarging the analytical region and by interpolating the new frame. The analytical performance of velocimetry was estimated by measuring the velocity from the flow dynamic image made artificially on the personal computer so as to simulate the flow of fluid containing a lot of small particles. As the results, the velocity range of the improved velocimetry became larger than that of the usual velocimetry. 21 refs., 13 figs., 1 tab.

  8. Analysis of flow and turbulence in high pressure spray by image processing technique. Gazo shori ni yoru koatsu funmunai ni okeru ryudo to midare no kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Yamaguchi, I. (Japan Automobile Research Institute, Inc., Tsukuba (Japan)); Nishida, M.; Nakahira, T.; Komori, M.; Tsujimura, K.

    1992-07-01

    The image processing technique (reported previously) developed for analyzing combustion in a diesel engine was applied to measuring flow and turbulent intensity in a high pressure spray. Copper vapor laser beam in a sheet form with a thickness of 0.2 mm was injected into the cross section of a spray center in a container. Photographs of the scattered lights of the beam is converted into digital values and analyzed using an image processing equipment. With the laser light emitting frequency set to 20 KHz at a maximum, the flow velocity is measured from changes in photographic image density in two subsequent photographs, and the turbulence intensity from changes in brightness intensity. As a result, it was clarified that the flow velocity and the turbulence intensity in the spray cross section increase with raising the spray pressure. Further discussions are being made on the measuring method, including changes in the image brightness associated with entrance and exit of spray particulates into the laser beam sheet, and effects of the laser beam sheet thickness on the measurements of the turbulence intensity. 6 refs., 6 figs.

  9. Dynamic stability analysis of circular arch subjected to follower forces with small disturbances; Judo kaju wo ukeru enkei arch no yuran ni yoru doteki kyodo to anteisei kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Fukuchi, N.; Okada, K. [Kyushu University, Fukuoka (Japan). Faculty of Engineering; Hirano, Y. [Sumitomo Heavy Industries, Ltd., Tokyo (Japan)

    1997-09-04

    This paper describes the deformation and dynamic stability of circular arch subjected to follower forces in a submerged membrane type marine structure reinforced by arch frames. Governing equations for finite deformations of the circular arch subjected to follower forces are introduced using an embedded curve coordinate, which are formulated by applying Galerkin method. In addition, equations of motion due to small disturbances under given condition of loading are introduced. Based on these equations, dynamic stability of the arch is analyzed by means of Runnge-Kutta-Gill method, to clarify the relationship between disturbances and instability regions and the resulting phenomena. Near the boundary regions of stability, both amplitude and cycle of deformation are greatly affected by the amplitude of disturbances. The dynamic instability is governed by the inverse symmetry primary mode with minimum characteristic frequency which is specific for the circular arch. The dynamic stability has high parameter dependency, and the instability regions have a complicated shapes. Although flattened arch has a smaller static critical load, it provides the dynamic stability against the disturbance. 5 refs., 10 figs.

  10. Technological development for super-high efficiency solar cells. Survey on the commercialization on analysis; Chokokoritsu taiyo denchi no gijutsu kaihatsu. Jitsuyoka kaiseki ni kansuru chosa kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    Tatsuta, M [New Energy and Industrial Technology Development Organization, Tokyo (Japan)

    1994-12-01

    This paper reports the survey results on analysis of super-high efficiency solar cells for practical use in fiscal 1994. (1) On the survey on crystalline compound solar cells, it was pointed out that the present study target is III-V compound semiconductor solar cell, and efficiencies of 36-39% are theoretically expected by use of two-junction cells. (2) On structure of super-high efficiency solar cells of 40%, selection of upper and lower cell materials for multi-junction cells, high-efficiency tandem Si solar cells, and the merit and possibility of light collection operation were surveyed, and their issues were discussed. (3) On physical properties of mixed crystalline semiconductors and characteristic evaluation of solar cells, impurities, trap center, minority carrier life, and applicability of supper lattice structure to high-efficiency solar cells were surveyed. (4) On fabrication technology of compound semiconductor solar cells, various problems of and approaches to electrode formation and antireflection film technologies, the meaning and issues of thin film substrate technology and continuous process, trial calculation of costs, safety, and resource problem were surveyed.

  11. Bayesian reliability analysis for non-periodic inspection with estimation of uncertain parameters; Bayesian shinraisei kaiseki wo tekiyoshita hiteiki kozo kensa ni kansuru kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    Itagaki, H. [Yokohama National University, Yokohama (Japan). Faculty of Engineering; Asada, H.; Ito, S. [National Aerospace Laboratory, Tokyo (Japan); Shinozuka, M.

    1996-12-31

    Risk assessed structural positions in a pressurized fuselage of a transport-type aircraft applied with damage tolerance design are taken up as the subject of discussion. A small number of data obtained from inspections on the positions was used to discuss the Bayesian reliability analysis that can estimate also a proper non-periodic inspection schedule, while estimating proper values for uncertain factors. As a result, time period of generating fatigue cracks was determined according to procedure of detailed visual inspections. The analysis method was found capable of estimating values that are thought reasonable and the proper inspection schedule using these values, in spite of placing the fatigue crack progress expression in a very simple form and estimating both factors as the uncertain factors. Thus, the present analysis method was verified of its effectiveness. This study has discussed at the same time the structural positions, modeling of fatigue cracks generated and develop in the positions, conditions for destruction, damage factors, and capability of the inspection from different viewpoints. This reliability analysis method is thought effective also on such other structures as offshore structures. 18 refs., 8 figs., 1 tab.

  12. Observations and analysis of free groundwater levels and groundwater pressure in landslide slopes. Jisuberi shamen no jiyu chikasuii, chikasuiatsu no kansoku to kaiseki ni tsuite

    Energy Technology Data Exchange (ETDEWEB)

    Yoshida, S; Nakano, T [Niigata Univ., Niigata (Japan). Faculty of Agriculture; Inaba, K [Niigata Univ., Niigata (Japan). Graduate School; Sato, O [Niigata Univ., Niigata (Japan)

    1991-12-25

    It is well known that the landslides in Tertiary systems abundantly found in Niigata Prefecture, etc., frequently occur especially in the snow melting season or the heavy rain season. For studying the occurrence of such landslides, exploration of the actual condition of groundwater and evaluation of the strength of earth are very important even when the landslide occurring mechanism can be presumed in a relatively simple way about the soil mechanics. Therefore, great importance is attached to the observation and investigation on the groundwater level and pressure at landslide sites and stability analyses have been actively performed. However, it is considered that several fundamental problems still exist in the method for estimating the groundwater level and pressure in landslide slopes from the observation method and data on groundwater levels and pressure (pore pressure). In this paper, these fundamental problems are examined on the basis of concrete observations made by the writers on landslide slopes at Matunoyamagoe and Higashimusikame landslide sites in Niigata Prefecture for the past several years. 6 ref., 6 figs., 2 tabs.

  13. Construction of analysis system on personal computer for slope disaster information using remote sensing technology. Remote sensing wo riyoshita pasokongata no shamen bosai joho kaiseki system no kochiku

    Energy Technology Data Exchange (ETDEWEB)

    Setojima, M [Kokusai Kogyo Co. Ltd., Tokyo (Japan); Goto, K [Nagasaki Universtiy, Nagasaki (Japan). FAculty of Engineering

    1991-08-25

    An analytical system with superposition of images which uses picture elements as a unit was developed to treat information obtained by remote sensing and other geographical information by superposing the images in order to extract the second information which expresses qualitatively and quantitatively the degree of slope disaster in the future, based on the first information about the damage caused by disaster and landform and geology. As necessary function for analytical system of the second information, precise correction of geometrical strain, superposition of images, visual reading treatment, and output of analytical result in map are listed and described respectively. Next, the detailed explanation of hardware and software of pilot system which used personal computer was given. The analytical procedure and result of land conditions around the landslide occurred at Nagano city in 1985 was shown. 3 refs., 1 fig., 1 tab.

  14. Dynamics of hydrogen induced blistering of a low carbon steel sheet by lamb waves analysis; Ramuha no teiryo kaiseki ni yoru hakubanteitansoko no suiso hare no dainamikkusu

    Energy Technology Data Exchange (ETDEWEB)

    Sato, Teruyoshi.; Takemoto, Mikio. [Aoyama Gakuin University, Tokyo (Japan). Faculty of Science and Engineering

    1999-06-15

    With the aim of studying the fracture dynamics of environmentally assisted fractures in thin plates, we developed a new source simulation method of the zeroth-order symmetric (or S{sub 0}-) Lamb wave using the experimental overall-transfer function of the system. The transfer function was determined by the time-domain deconvolution of detected S{sub 0}-Lamb component by the artificial fracture source of a compression -type PZT element whose vibration kinetics was estimated by the iteration so that the S{sub o}-waveform detected. Hydrogen induced blistering was found to be caused by the succession of fast Mode-I fracture with source rise times from 0.6 to 1.0{mu}s. The crack volume estimated by the source simulation corresponded to that of fine blistering with an opening displacement of 5{mu}m. As the estimated fracture kinetics of hydrogen blistering coincide with those of delayed fracture of high tension low alloy steel under tensile loading, the kinetics of first and micro-fractures and blistering induced by hydrogen gas precipitation appears to be independent on the hydrogen solubility and strength of steels, the applied stresses and the orientation of cracks. (author)

  15. FY1999 Meeting of The Society of Heating, Air-Conditioning and Sanitary Engineering of Japan. Air flow analysis II; 1999 nendo gakujutsu koenkai gaiyo. Kiryu kaiseki 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-12-05

    B-4 reported the result on particle size distribution experiment and numerical calculation with FEM and {kappa}- {epsilon} model using a welding simulation equipment for generation and removal of welding fume in a narrow site. Discussion was held on the position of an exhaust hood. B-5 reported the study results on indoor air flow conditions derived from a movable nozzle air conditioning system by model experiment and numerical analysis. Disagreement of both results between the experiment and calculation in the case of two diffusing nozzles attached at 30 degrees toward the inside was improved by shortening a sampling time for calculation. B-6 reported the study results on some parameters such as wind velocity, flow rate and inlet position, and the energy saving effect of an air curtain (wall outlet, floor inlet) to control air conditioning areas for a part of large spaces by numerical analysis of air flow. Discussion was held on calculation of 2-D flow and layered flow. B-7 is the 5th research report on measurement of air flow conditions such as measurement of large space environment by video camera and balloon. Study on the camera for automatic measurement, and the identification technique of balloon positions was reported. (translated by NEDO)

  16. Optimization of the catalytic converter internal flow by using 3D-CFD; Sanjigen nagare kaiseki ni yoru shokubai converter nai nagare no saitekika

    Energy Technology Data Exchange (ETDEWEB)

    Toi, M; Sugiura, S [Toyota Motor Corp., Tokyo (Japan)

    1997-10-01

    By using computational fluid dynamics and statistical quality control method, we investigated the contribution of front and rear catalytic converter cone shape for the pressure loss and the partial flow, also led the optimal terms and the predictional formulations efficiently. According to this, we can investigate the optimal position of the catalytic converter from the planning. 8 figs., 6 tabs.

  17. Study of transient in-cylinder air motion under motoring condition with diesel engine; Diesel engine no motoring ji no tonai ryudo kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Kitasei, T; Nakagawa, T [Mitsubishi Motors Co., Tokyo (Japan); Yamazumi, N [Ryoyu Keisan Co., Tokyo (Japan)

    1997-10-01

    The transient in-cylinder air motion have been investigated for reducing exhaust emissions and improving engine performance. A commercial CFD code was used for this purpose. For analyzing under engine motoring condition, the numerical model has a moving piston, intake and exhaust ports with moving valves. As result, exhaust port performance may be analyzed under steady condition, but intake port performance have to be analyzed under unsteady condition. Because transient in-cylinder air motion during intake process is different from steady in-cylinder air motion under influence of piston surface and air viscosity. 4 refs., 11 figs.

  18. Study of heart rate variability in driving situation by fractal analysis; Fractal kaiseki ni yoru untenchu no shinpaku hendo no bunseki

    Energy Technology Data Exchange (ETDEWEB)

    Hirata, Y; Nagaoka, M [Mazda Motor Corp., Hiroshima (Japan)

    1997-10-01

    This paper will explain method of fractal analysis for heart rate variability, as measuring method of mental stress in vehicle driving. In the previous, although there was a measuring method of mental stress by RSA, a issue arise such as reliability of analysis, because driver`s heart rate affect by respiration and muscle motion as well. We have established a method to measure mental stress by fractal dimension. And tried it is the proving ground and public road driving. We have confident that it is more reliable than RSA to quantify driver`s mental stress and fatigue. 9 refs., 9 figs., 1 tab.

  19. Summary of [alpha]-FLOW, a general purpose three-dimensional fluid analyzing system. Han[prime]yo sanjigen ryutai kaiseki system [alpha]-FLOW no gaiyo

    Energy Technology Data Exchange (ETDEWEB)

    Koike, H [Fuji Research Institute Corporation, Tokyo (Japan)

    1992-08-01

    The [alpha]-FLOW is a three-dimensional fluid analyzing software developed from cooperations among research institutes of private business companies and universities in Japan under the assistance from the Ministry of International Trade and Industry. This paper describes its summary and features. The system is a discrete system utilizing a supercomputer and a work station. The analysis modules incorporated in the system include those for non-compressive fluid analysis, compressive fluid analysis, analysis of non-compressive fluid including free surface, analysis of flows including combustion and chemical reactions, substance migration analysis, and heat transfer analysis. It has a feature that even non-specialists can analyze fluids easily as a result of the development of an expert system to support the numerical analysis. Development of the input data preparing system enables to utilize the work station to process from shape modeling to grid generation, and from inputting analyzing condition data to calculating the flows and outputting the calculation result, all in dialogue modes. An open architecture was adopted. 27 refs., 7 figs., 10 tabs.

  20. Analysis and model-tests on vortex-induced oscillation of bridges; Kyoryo no uzu reishin ni kansuru sanjigen oto kaiseki to fudo jikken

    Energy Technology Data Exchange (ETDEWEB)

    Yamamura, N. [Hitachi Zosen Corp., Osaka (Japan); Ogasawara, M. [Kansai Electric Power Co. Inc., Osaka (Japan); Shiraishi, N. [Maizuru College of Technology, Kyoto (Japan); Nanjo, M.

    1996-07-21

    In order to predict the three-dimensional response to vortex-induced oscillation of bridges, a model was investigated using the aerodynamic force coefficient including vortex-induced and self-excited forces, and the nonlinear response coefficient expressing constancy of response to vortex-induced oscillation. In the analysis, change of frequency in wind by the self-excited force, aerodynamic damping term, effect of the mode, and correlation of the vortex-induced force along member axis were taken into account. The aerodynamic force and nonlinear response coefficients were identified from the homogeneous and turbulent flow results of wind tunnel tests using a two-dimensional spring support rigid body model with varied damping factor. The aerodynamic damping term can be estimated from the nonlinear aerodynamic force coefficient, but it was enough to calculate it from the quasi-stationary coefficient in general bridge profiles. The correlation of the vortex-induced force was obtained from measurements of the vertical variation components of trailing flow under the resonance state, or the pressure distribution of the member surface. When comparing to the wind tunnel test of three-dimensional model of cable-stayed bridge, the response amplitude by the present analysis method was consistent well with the test results rather than by the method in which the amplitude of two-dimensional model was corrected. 10 refs., 4 figs., 3 tabs.

  1. Ultimate strength analysis of long-span cable-stayed bridges; Chodai chachokyo no shukyoku kyodo kaiseki to kyodo ni kansuru ichikosatsu

    Energy Technology Data Exchange (ETDEWEB)

    Xie, X.; Yamaguchi, H. [Saitama Univ., Urawa (Japan)] Nagai, M. [Nagaoka Technical Coll., Niigata (Japan)

    1998-07-21

    Recently, span of cable-stayed bridges has been getting loner and longer, present situation is that cable-stayed bridges with span 600 to 800m class have been built inside and outside the country, and accurate determination of its ultimate strength has been an important problem statistically. However, concrete design method for evaluating load bearing stress of long-span cable-stayed bridge. Particularly of the main beam whose axial stress is dominating, has not been established so far. As for cable-stayed bridge, even for long-span, effect of plasticization of cross section on ultimate strength is severe because there is little effect of geometric nonlinearity and it is thought that accurate evaluation of ultimate strength only by elastic finite potential analysis is difficult. Accordingly, it is necessary to study the behavior by using combined nonlinear analysis considering the nonlinearity of the material in order to evaluate the safety and economy to long-span cable-stayed bridge. In this report, 3 dimensional analysis method was formularized taking into account the combine nonlinearity of multi-box girder and analysis program of ultimate strength behavior of long-span cable-stayed bridge was developed. 19 refs., 17 figs., 2 tabs.

  2. Analysis of vibration characteristics of a prestressed concrete cable-stayed bridge using strong motion observation data. Jishin kansoku ni motozuku PC shachokyo no shindo tokusei no kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Inatomi, T. (Port and Harbour Research Institute, Kanagawa (Japan)); Takeda, T.; Obi, N.; Yamanobe, S. (Kajima Corp., Tokyo (Japan))

    1994-05-31

    Records of seismic observation were analyzed for the purpose of proving the validity of antiseismic design for a prestressed concrete (PC) cable-stayed bridge. This bridge is a three span continuous PC cable-stayed bridge of 498 m in bridge length, and is constructed on alluvial soft ground. The seismometer used is a servo type accelerometer. The observed frequency and mode of seismic vibration are in good agreement with those in the analysis and hence the validity of modelling of the structure in designing was confirmed. It was also confirmed that the bending vibration and torsional vibration of the main girder are separated as designed. However, some points such as a large difference in the observed vibration and analysed vibration in the mode accompanying rotation of the base are listed as problems to be solved in antiseismic design. In order to investigate the attenuation constant of the upper structure, a seismic wave response analysis was performed and its results were compared with observed ones. When the attenuation constant is assumed to be 2%, agreement of data between analysis and observation is good, and it is considered that the attenuation constant of the upper structure only without the effects of attenuation of energy escape from the base and crack generation in concrete was about 2% in the observed earthquake (maximum acceleration on the ground: 51 Gal). 8 refs., 9 figs., 2 tabs.

  3. Bayesian reliability analysis for non-periodic inspection with estimation of uncertain parameters; Bayesian shinraisei kaiseki wo tekiyoshita hiteiki kozo kensa ni kansuru kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    Itagaki, H [Yokohama National University, Yokohama (Japan). Faculty of Engineering; Asada, H; Ito, S [National Aerospace Laboratory, Tokyo (Japan); Shinozuka, M

    1997-12-31

    Risk assessed structural positions in a pressurized fuselage of a transport-type aircraft applied with damage tolerance design are taken up as the subject of discussion. A small number of data obtained from inspections on the positions was used to discuss the Bayesian reliability analysis that can estimate also a proper non-periodic inspection schedule, while estimating proper values for uncertain factors. As a result, time period of generating fatigue cracks was determined according to procedure of detailed visual inspections. The analysis method was found capable of estimating values that are thought reasonable and the proper inspection schedule using these values, in spite of placing the fatigue crack progress expression in a very simple form and estimating both factors as the uncertain factors. Thus, the present analysis method was verified of its effectiveness. This study has discussed at the same time the structural positions, modeling of fatigue cracks generated and develop in the positions, conditions for destruction, damage factors, and capability of the inspection from different viewpoints. This reliability analysis method is thought effective also on such other structures as offshore structures. 18 refs., 8 figs., 1 tab.

  4. FY 2000 report on the results of the R and D of fundamental technologies for semi conductivity applications; 2000 nendo chodendo oyo kiban gijutsu kenkyu kaihatsu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-05-01

    In relation to the project on the R and D of fundamental technologies for semi conductivity applications, the FY 2000 results were summed up. As to the study of the high temperature superconductivity mechanism, it was found out that a theoretical model of the strong scattering limit in d-wave superconductor can be used for the breaking of superconductivity due to Zn impurities. Concerning the study of the critical current mechanism, the elucidation was proceeded with of the magnetic flux pinning and grain-boundary conduction mechanism. Relating to the development of element technology of bulks with great electromagnetic force, the mechanical strength of superconducting bulk materials was raised to 100MPa or more by the epoxy resin impregnation method. As to the development of the basic technology for fabrication of high next-generation current conductors, the expansion was confirmed of conditions for growing single grains in the zone-melt process for very fine filaments. About the development of technology of single crystal substrates, in the development of the pseudo single crystalline film growth process by LPE method, a yield ratio of high quality crystal of 63% was achieved. Concerning the development of technology of thin film/multi-layer, the area of uniform composition/thickness of NdBa{sub 2}Cu{sub 3}O{sub 7-x} MOCVD films was enlarged up to 20mm square. (NEDO)

  5. Possibility of a high-T{sub c} superconducting bulk magnet for maglev trains in the future; Koonchodendo baruku jishaku no jikifujoshiki tetudo heno oyo kanosei

    Energy Technology Data Exchange (ETDEWEB)

    Fujimoto, H. [Railway Technical Research Institute, Fundamental Research Division, Tokyo (Japan)

    1999-11-25

    Superconducting magnets made of high-T{sub c} superconductors are promising for industrial applications. It is well known that REBa{sub 2}Cu{sub 3}O{sub 7-x} superconductors prepared by melt processes have a high critical current density, J{sub c}, at 77K and high magnetic fields. The materials are very prospective for high magnetic field application as a superconducting permanent/bulk magnet with liquid-nitrogen refrigeration. LREBaCuO bulks, compared with REBaCuO bulks, exhibit a larger, J{sub c} in high magnetic fields and a much improved irreversibility field, H{sub irr}, at 77K. In this study, we discuss the possibility and trapped field properties of a superconducting bulk magnet, as well as the melt processing for bulk superconductors and their characteristic superconducting and mechanical properties. One of the applications is a superconducting bulk magnet for future magnetically levitated (Maglev) trains. (author)

  6. State-in-the-art of applications of shock wave research and its future; Shogekiha no oyo gijutsu no genjo to shorai

    Energy Technology Data Exchange (ETDEWEB)

    Takayama, K. [Tohoku Univ., Sendai (Japan). Inst. of Fluid Science

    1999-03-15

    A shock wave appears when the release of accumulated energy is instantaneous. For instance, it accompanies gunpowder explosion, electric discharge, laser beam convergence, collision of high-speed objects, release of high-pressure gas, and supersonic flight. The shock wave research center of Institute of Fluid Science, Tohoku University, is engaged in researches to elucidate the basics of various shock wave phenomena and to apply the fruit to engineering, science, and medicine. In this report, some examples of recent application studies at the center are described, and the trend of shock wave researches in the future is introduced. The ultimate state of the stagnation point of a nozzle flow simulating a reentry into the atmosphere is produced by shock wave compression in a free piston shock tube which is a ground-borne experimental apparatus. Los Alamos National Laboratory, U.S., succeeded in generating metallic hydrogen of a crystalline structure by subjecting liquid hydrogen to shock wave compression, in which effort a two-stage light gas gun augmented with an accelerator was operated. A high-performance two-stage light gas gun can simulate on the ground a collision of space debris in a high vacuum. Other researches involve the elucidation of the mechanism of sonic noise. (NEDO)

  7. FY 2000 research and development on DSRC/ITS application systems for vehicles; 2000 nendo DSRC/ITS shasaiki no oyo gijutsu kenkyu kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Described herein are the FY 2000 results of the research and development project aimed at application of the large-capacity, high-speed, bilateral dedicated short-range communication (DSRC) techniques, used for communication between running vehicles for electronic toll collection (ETC), to various types of ITS. The current ETC data alone is useful to apply the tollgate passage histories to the management of the vehicle operation. For practical application of the ETC tollgate passage data by transportation companies, developing the IC card readers installed at their offices and examining methods of interconnecting the DSRC-based vehicle operation management systems and ETC are effective. The field demonstration tests are conducted for DSRC-based onboard ETC equipment in real environments. The standards or guidelines are drafted for the four research items studied for application of DSRC/ITS onboard equipment, based on the onboard system architectures. More concretely, the standard specifications are drafted for the two items of the DSRC-applied platforms and functional diversification of the onboard ITS equipment, and the guidelines are drafted for the other two items of application of the DSRC systems for paying various fees and application of the DSRC systems for vehicle operation management. (NEDO)

  8. Achievement report on research and development of optics-aided measurement/control system; Hikari oyo keisoku seigyo system no kenkyu kaihatsu ni kansuru hyoka hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1986-03-01

    The project aims to establish technologies for putting the above-named system to practical use. Such a system will measure, transmit, and control, with safety and stability by use of optical technologies, industrial process related information to be generated in certain areas such as industrial complexes and very large plants, the information including images, temperatures, flow rates, constituents, etc. Total system evaluation was performed in demonstration tests for appropriateness conducted for 32 systems in fiscal 1980 and 10 systems in fiscal 1981. Studied in the development of element technologies are opto-electronic integrated circuits (OEIC), semiconductor laser devices, light-intercepting devices, optical transmission paths, dielectric light switches, and optical sensors. For OEIC, in particular, since it is believed to be the nucleus of an optical application system, an optical technology joint research office is established, where efforts center on the substrate crystal growth technology, process technology, and crystal/process evaluation technology. (NEDO)

  9. Media Choice in Environmental Information Dissemination for Solid Waste Management among Policy Formulators and Implementors: A Case Study of Oyo State, Nigeria

    Science.gov (United States)

    Akintola, B. A.; Temowo, O. O.; Ajiboye, J. O.

    2009-01-01

    Environmental information has been described as central to the issues of solid waste management and disposal. This study investigated the availability and accessibility of environmental information to the solid waste policy formulators and implementors with regard to the media/channels used for disseminating environmental information to the…

  10. Construction of educational application system for calligraphy master based on virtual reality; Virtual reality wo mochiita shodo shutoku no tame no kyoikuteki oyo system no kochiku

    Energy Technology Data Exchange (ETDEWEB)

    Yoshida, T.; Muranaka, N.; Imanishi, S. [Kansai University, Osaka (Japan)

    1997-10-20

    Technique of virtual reality has been becoming popular in various fields including education because of its remarkable technique progress. There are the three useful elements of `presence`, `interaction` and `autonomy` in realizing the virtual reality. Here, we are focusing on the `presence` in constructing a simple supporting system for calligraphy education. We take advantage of the virtual image with reality to use as an educational interface because the virtual image and the real image are overlapped by showing the visual scene in the system. It is general that the unity of the virtual image and the real image has been processed as the stationary pictures by using `See-through HMD` and so on. In this paper, by using half mirror in stead of using the HMD with restraint, we are released from its restrainable sense. The virtual image and the real image are laid to overlap as the mobile pictures. The virtual hand replays the character inputted on the tablet by the excellent calligrapher. A calligraphic trainee is practicing overlapping the virtual hand which is reflected at the half mirror, while the trainee is doing the character on the tablet in the handwriting. The trainee is repeatedly practicing with feedback and is getting better in handwriting the character. It is shown in the good expermental results that the system has a proven effectiveness. 9 refs., 12 figs., 2 tabs.

  11. Development and application of controlled source audiofrequency magneto telluric method. Results of experiment at Akagi, Sakurajima, Kuju volcanos. Shingogen seigyo chijikichidenryuho (CSAMT-ho) no kaihatsuto oyo

    Energy Technology Data Exchange (ETDEWEB)

    Kusunoki, Ken' ichiro; Suzuki, Koichi

    1988-03-01

    Central Reserch Inst. of Electric Power Industry has carried out prospecting experiments, in various places, with magneto telluric method (MT method) which employs natural electromagnetic wave, and has confirmed the effectiveness of the method in estimation for location of faults, distribution range of rocks, and structure of geothermal sources. With increase in accuracy, the MT method, which was suitable for the approximate prospecting in wide areas, was considered to become useful for determination of detailed geothermal structures directly under prospective points of geothermal wells. For the increase in accuracy, it was necessary to increase the kind and intensity of electromagnetic wave. Consequently, we developed, first as domestically, an unit of controlled source audiofrequency magneto telluric method. The unit, generating artificially electromagnetic wave, is useful for underground structure prospecting. Fundamental experiment on transmission and reception of electromagnetic wave was carried out as preparations for full-scale prospecting, then the structures of volcanos were prospected resulting in the determination of thickness distribution of shirasu layers and heat transfer route from magma reservoirs up to ground surface. (19 figs, 11 refs)

  12. Current status and prospect on photo-catalyst application in environmental problems; Kankyo mondai ni okeru hikari shokubai oyo no ganjo to tenbo

    Energy Technology Data Exchange (ETDEWEB)

    Watanabe, T. [Toto Ltd., Kitakyushu (Japan)

    1995-09-30

    This paper summarizes application of photo-catalysts in environmental problems. The paper lists examples of the application in residential environments. Photo-catalytic decomposition is possible by using ultraviolet rays contained in room illumination if the bacterial presence is sparse. The examples thereof may be cited as follows: if colon bacilli are suspended on a tile with TiO2 photo-catalyst sintered in it and exposed to room illumination, the bacteria are disinfected; using photo-catalysts in a bathroom suppresses deposition of Pseudomonas aeruginosa; a photo-catalyst tile (TiO2 loaded with Cu) and light irradiation reduce intensity of tobacco smoke odor; and adsorbents may be used simultaneously if intermediate products are odor generating substances. The examples of applying photo-catalysts to regional environments may be quoted as follows: growth of algae in a Petri dish is suppressed by presence of Cu loaded TiO2 under room illumination; this leads to an expectation on its effect in a relatively clean water environment; glass beads loaded with a TiO2 photo-catalyst placed in a gold fish breeding tank reduces turbidity, the number of colon bacilluses, and COD value; and the mortality in gold fish shows no change. With an objective of application to exterior building materials, photo-catalyst applied tiles were left outdoors for 160 days. Nitric acid ions were detected that are thought to have been generated by decomposition of microorganisms that have deposited on the tiles. 6 refs., 5 figs., 3 tabs.

  13. Numerical method to calculate flow-induced vibration in turbulent flow. 3rd Report. Analysis of vortex-induced vibration in an array of elastically supported tubes; Ranryuba ni okeru ryutai kozotai rensei shindo kaiseki shuho no kaihatsu. 3. Kangun ni okeru uzu reiki shindo kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Sadaoka, N.; Umegaki, K. [Hitachi, Ltd., Tokyo (Japan)

    1996-01-25

    A vortex-induced vibration of an array of elastically supported tubes is simulated in two-dimension by using a flow-induced vibration analysis program, which was developed in order to evaluate flow-induced vibration in various components such as heat exchangers. From a comparison of calculated results and experimental data, the following points are observed. (1) For the calculated results in a 5 {times} 5 square array, the flow pattern surrounding the first-row tubes is markedly different from that observed in the second-row or third-row tubes. This flow pattern is the same as that obtained from the experiment. (2) All tubes begin to oscillate due to unsteady fluid force and the oscillating mode is different for each row of tubes. These oscillation patterns show the same tendency in the experiments and it is concluded that the developed method can simulate vortex-induced vibration in an array of elastically supported tubes. 19 refs., 10 figs., 1 tab.

  14. Report for fiscal 1981 on comprehensive survey for nationwide geothermal resources. Survey on radar imaging method - geothermal conception design (Associated material 3 - materials related to U.S. geothermal analysis contractors and consultants); 1981 nendo zenkoku chinetsu shigen sogo chosa hokokusho. Radar eizoho chosa (chinetsu kaiseki gainen sekkei futai shiryo 3 (Beikoku chinetsu kaiseki contractor oyobi consultant kankei shiryo))

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1982-10-01

    This paper summarizes the U.S. geothermal analysis contractors, including the Aero Service Corporation, the EG and G Group, the QEB Group, and the Republic Geothermal, Inc., and the consultants, including the Remote Sensing Consultants. For the Aero Service Corporation, the paper states histories of and books written by major personnel. For the EG and G Group, the paper states the outlines of such companies as EG and G Services, EG and G Geometrics, Mars Associates, Inc., and UURI, as well as histories of and books written by major personnel. For the QEB Group, the paper states the outlines of such companies as QEB, Inc., and Eureka Resource Associates, Inc. as well as histories of and books written by major personnel. For the Republic Geothermal, Inc., the paper states the company outline, histories of and books written by major personnel. For the Remote Sensing Consultants, the paper states the history of and books written by Dr. R.J.P.L. Lyon. (NEDO)

  15. Analysis and evaluation of data to accompany the development of geothermal water use power plant, etc. Analysis and evaluation of polymeric materials exposed to geothermal heat at depths; Nessui riyo hatsuden plant nado kaiahtsu ni tomonau data no kaiseki hyoka. Shinbu chinetsuyo kobunshi zairyo no kaiseki hyoka

    Energy Technology Data Exchange (ETDEWEB)

    Kenmochi, K.; Takahashi, J.; Takayanagi, H.; Tsuda, H.; Nagai, H.; Takeuchi, K. [Agency of Industrial Science and Technology, Tokyo (Japan); Nagasawa, C. [Kumamoto Prefectural Industrial Technology Center, Kumamoto (Japan); Hamada, T. [Science University of Tokyo, Tokyo (Japan). Faculty of Industrial Science and Technology

    1998-11-20

    Remaining life assessment technologies for polymeric materials for geothermal power generation and methods for improving their heat resistance are reviewed, and concepts of scale-free technologies for FRP (fiber-reinforced plastic)-sandwiched pipelines for hot water transportation are described. Materials based on PTFE (polytetrafluoroethylene) and NBR (acrylonitrile-butadiene rubber) are chosen for use as DHM (down-hole motor) sealing material and for application to the stator. With PTFE as the matrix, four candidates are prepared, which are additive-free PTFE, and GF/PTFE, GF/CF/PTFE, CF/PTFE, each containing 20w% GF (glass fiber) and/or 20w% CF (carbon fiber). With NBR serving as the matrix, two candidates are prepared, which are NBR-A containing 20w% aramid fiber and NBR-W which is a vulcanized NBR-A. External force, heat, light, and mud are named as the degradation factors, and each factor and some combinations of external force, heat, and light are repeatedly imposed on the materials. During the effort to develop an apparatus for simulating geothermal circumstances in which the factors will affect the materials in complicated ways, a life assessment technique is developed for such polymeric materials. A technology is developed for providing polymeric rubber elastomer with a heat resistant feature. A study is made to replace transportation pipelines for injection wells with FRP sandwiched pipelines. (NEDO)

  16. Analysis and evaluation for practical application of photovoltaic power generation system. Analysis and evaluation for development of extra-high efficiency solar cells (fundamental research on extra-high efficiency Si solar cells); Taiyoko hatsuden system jitsuyoka no tame no kaiseki hyoka. Chokokoritsu taiyo denchi no gijutsu kaihatsu no tame no kaiseki hyoka (chokokoritsu silicon taiyo denchi gijutsu kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    Sekikawa, T; Suzuki, E; Ishikawa, K; Takato, H; Yui, N; Shimokawa, R [Electrotechnical Laboratory, Tsukuba (Japan)

    1994-12-01

    Described herein are the results of the FY1994 research program for analysis and evaluation for development of extra-high efficiency silicon solar cells. It is necessary for development of extra-high efficiency Si solar cells to extend as far as possible service life of minority carriers and to develop the evaluation techniques. Noting photoluminescence (PL) observable even with Si, the method of evaluating characteristics of minority carriers, which are not limited in samples, is developed to experimentally determine their service life from transitional response of the PL characteristics. Si has an extremely low quantum effect, because it is an indirect transitional semiconductor, and needs measurement of very high sensitivity. A rapid heat annealing apparatus and others to generate carriers in the infrared and ultraviolet regions are provided in consideration that these are possible means to increase efficiency. These possibilities will be pursued by developing the annealing techniques. 1 fig.

  17. Analysis and evaluation for practical application of photovoltaic power generation system. Analysis and evaluation of peripheral technology for photovoltaic power system (analysis and evaluation on photovoltaic systems); Taiyoko hatsuden system jitsuyoka no tame no kaiseki hyoka. Shuhen gijutsu kaihatsu no tame no kaiseki hyoka (taiyoko hatsuden system shingata chikudenchi)

    Energy Technology Data Exchange (ETDEWEB)

    Kurokawa, K; Endo, E; Tsuda, I; Nakamura, K; Sugiyama, Y; Nakazawa, S; Takaku, K; Yanagisawa, T; Kojima, T; Shimizu, K; Koyanagi, T; Onda, N; Nozaki, K; Negishi, A; Kaneko, Y [Electrotechnical Laboratory, Tsukuba (Japan)

    1994-12-01

    Described herein are the results of the FY1994 research program for analysis and evaluation of new storage batteries for photovoltaic power systems. Quantitative analysis and evaluation are made for introduction of intermittent operational mode in the conventional power supply system in which electrolyte units are connected in parallel and for improved performance by bubbles flowing into the line that supplies the electrolyte to the stack, in order to establish the configurations of and operational procedures for the redox flow batteries. The study on development of redox battery compares the Pb-Sn alloy felt collector with carbon fiber, Pb-Sb alloy felt and the lattice for the conventional lead acid battery, in order to optimize the new lead felt battery. As a result, it is found that the Pb-Sn alloy felt collector is better than any other device tested, because of its higher freedom with respect to electrode shape and battery size. The study on reliability evaluation of amorphous solar cells tests photoelectric conversion efficiency of a-Si solar cells, in order to elucidate the phenomena where degradation and rejuvenation compete with each other under weak light irradiation conditions. 8 figs., 1 tab.

  18. Analysis and evaluation for practical application of photovoltaic power generation system. Research and development of elemental technologies for thin-type solar cells; Taiyoko hatsuden system jitsuyoka no tame no kaiseki hyoka. Usugata takessho taiyo denchi jitsuyoka no tame no kaiseki hyoka

    Energy Technology Data Exchange (ETDEWEB)

    Sekikawa, T; Shimokawa, R; Yui, N; Takato, H; Takahashi, T; Ishii, K; Suzuki, E; Nagai, K; Kawanami, H; Tanimoto, J; Sakuta, H; Iwata, Y; Saito, N; Koyama, K; Sawada, S [Electrotechnical Laboratory, Tsukuba (Japan)

    1994-12-01

    Described herein are the results of the FY1994 research program for analysis and evaluation for thin substrate polycrystalline solar cells. In order to analyze the structures of the grain boundaries in and interfaces with the cell substrate, and their effects on electrical activity, the photoluminescence (PL) measurement which enables spectroscopic analysis is applied to electromagnetically cast Si crystals. There are good correlations among PL luminous intensity, MBIC output and dislocation density for the grain boundary which contains many strains and serves as the dislocation source, because carriers in such a grain boundary easily disappear to reduce its luminous intensity at the band ends. Concrete scenarios for realizing thin-film silicon solar cells of high efficiency are presented, based on the analysis of the light-contained thin-film silicon solar cells of high output current, made in the previous year on a trial basis. An alumina substrate of high reflectivity is produced by the experiments of combining various devices. It is expected to realize high output current for the thin-film solar cells. 3 figs.

  19. Analysis and evaluation for practical application of photovoltaic power generation system. Analysis and evaluation for extra-high efficiency solar cells (research on new concentrator modules); Taiyoko hatsuden system jitsuyoka no tame no kaiseki hyoka. Chokokoritsu taiyo denchi no gijutsu kaihatsu no tame no kaiseki hyoka (shingata shuko module)

    Energy Technology Data Exchange (ETDEWEB)

    Tanimoto, J; Sakuta, K; Sawada, S; Yaoita, A [Electrotechnical Laboratory, Tsukuba (Japan)

    1994-12-01

    Described herein are the results of the FY1994 research program for analysis and evaluation of concentrator modules for extra-high efficiency solar cells. The outdoor exposure tests have been under way for 3 years for fluorescent plates, as part of the research program for development of materials and elementary techniques, and essentially no degradation has been observed by the perylene pigment test. Coupling of the fluorescent concentrator and solar cell units is investigated for the coupling position and method, to theoretically analyze geometrical coupling efficiency, where they are coupled at the bottom faces in consideration of easiness of module fabrication. It is demonstrated that a high coupling efficiency can be realized when the cell is sufficiently wide relative to thickness of the fluorescent plate. The coupling method is experimentally examined using transparent silicon gel. A prototype module having the same size as the commercial module (420mm by 960mm) is made on a trial basis, where a total of nine 20mm-thick cells are cut out of a single-crystalline silicon solar cell, 100mm by 100mm in size, and are connected to concentrators at the bottom faces. It shows 2.3 times increased output by the test using a large-area solar simulator. 2 figs.

  20. Numerical modeling of historical change of volcanic heat sources: Numerical modeling of heat and mass transport up to 1000 degree C; Kazansei netsugen no keiji henka no shumyureshon kaiseki: 1000 degree C madeno netsu{center{underscore}dot}ryutai shumyureshon kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Hanano, Mineyuki [JMC Geothermal Engineering Corp., Iwate (Japan)

    1998-12-01

    Temperature structure and its historical change around volcanos has been of interest for volcanology, geothermal development, etc. Magmatic intrusives have temperatures ranging from 700 to 850 degree C. Thus, there exists super-critical fluid around them. Numerical modeling of temperature changes around young volcanos and their heat sources thus requires treatment of the super-critical fluid. We describe one method for effective treatment of the super-critical fluid in the numerical modeling of porous media for the purpose of solving large-scale high-temperature problems of such phenomena. (author)

  1. Report on achievements of research and development of a technology to apply human senses to measurements in fiscal 1995. 2. Main issue (Research and development of a human sense index applying technology); 1995 nendo ningen kankaku keisoku oyo gijutsu no kenkyu kaihatsu seika hokokusho. 2. Honronhen (ningen kankaku shihyo oyo bijutsu no kenkyu kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    This paper describes the achievements in fiscal 1995 on research and development of a human sense index applying technology. Total system design and fabrication were launched on a human comfort meter. A resin-made human shaped body attached with warm heat sensing elements and a software logic for a control system for whole body movements were devised. Fabrication was carried out on a driver's seat, a simulated visual field generating device and a system to calculate the machine's movements on a real time basis to perform experiments to evaluate operation reliability by using a 25-ton lifting crane. A system was created that can measure in situ the physiology, psychology and activity reactions. An experimental environment was set that can be operation reliability evaluation indexes by measuring physiological and psychological reactions during crane works, and selection was launched on physiological index candidates. Elucidation was made on characteristics of parallax of both eyes being the main visual function to structure the VR space. At the same time, sensual and physiological verification was given on how important the conditions presented by merged images created by the parallax of both eyes can be in raising the reality of the VR space. The paper also describes the relationship between muscle fatigue and physiological indexes. (NEDO)

  2. Report on the achievements in fiscal 1999. Research and development on a basic technology to apply superconductivity (Research and development on a basic technology to apply superconductivity); 1999 nendo chodendo oyo kiban gijutsu kenkyu kaihatsu seika hokokusho. Chodendo oyo kiban gijutsu kenkyu kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-05-01

    The development of a basic technology to improve superconductivity characteristics has performed (1) studies on the high-temperature superconductivity mechanism, (2) studies on the critical current mechanism, and (3) search for materials. In Item (1), composition and temperature dependence were investigated by measuring superconductivity gap and change in the electron state of pseudo gap using photo-electron spectra and Raman scattering spectra. In Item (2), magnetic flux behavior in the vicinity of the irreversible line was investigated on magnetic flux dynamics of Bi2212 by measuring magnetic resistance and magnetization. High viscosity condition having strong magnetic flux liquid zone was discovered. In Item (3), Sr was used in place of Ba as the constituting element, and several new mercury-based superconductors were synthesized successfully by using the high pressure synthesizing method. In developing superconductive bulk materials and wire materials, elucidation was given on (1) an element technology for high magnetic power bulk materials, (2) an element technology for high critical temperature bulk materials, (3) a fundamental technology for manufacturing next generation wire materials, (4) a fundamental technology for manufacturing next generation large current conductors, and (5) growth mechanism in wire material crystals. Development of laminating and processing technologies for superconductive materials has worked on (1) a single crystal substrate technology, (2) a thin film lamination technology, (3) a standard bonding technology, (4) an advanced bonding technology, and (5) a thin film and bond evaluation technology. (NEDO)

  3. Fiscal 1999 survey report. Survey of leading countries' approaches to biomass energy development; 1999 nendo shuyokoku ni okeru biomass energy kaihatsu eno torikumi ni kansuru chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    The survey aims to help Japan deliberate its future biomass energy development strategy including the course Japan is to follow in its research and development of biomass energy by clarifying leading countries' approaches to the subject matter and trends of their research and development efforts in this connection. The states of biomass energy development in the U.S. and Europe are reported. In the U.S., President Clinton issued Executive Order 13134 on August 12, 1999, regarding bio-based products and bioenergy development. In this country, bioenergy and bio-based production technologies have developed to reach a stage where business pays, and commercial plants are in service. The U.S. Administration mentions as a strategy the efficient development of the bioenergy industry. In Europe, where resources are versatile and local, it is difficult to assess the economy of scale, and small-scale development efforts are being accumulated. Practical technologies under development mostly involve direct combustion. European measures are similar to U.S. measures in that such political goals as local development and employment promotion are firmly woven into them. (NEDO)

  4. Expression of iNOS, eNOS, and peroxynitrite-modified proteins in experimental anti-myeloperoxidase associated crescentic glomerulonephritis

    NARCIS (Netherlands)

    Heeringa, P; van Goor, H; Moshage, H; Klok, PA; Huitema, MG; de Jager, A; Schep, AJ; Kallenberg, CGM

    Nitric oxide radicals are recognized as important mediators in various physiological and pathophysiological processes. During inflammation, increased amounts of nitric oxide (NO) are produced, but it is unclear whether NO radicals are either protective or harmful. To obtain more insight into the

  5. Study on the effect of micro-gravity on bio-functions; Seitai kino eno bisho juryoku no eikyo ni kansuru kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    The effect of micro-gravity on bio-functions and vital reaction was studied using the facility of Underground Gravity-free Experiment Center Co. On the effect on osteoblast shape and gene expression, although fluorochrome reacting with Ca was well taken into cells, no significant difference in Ca content in cells was observed before/after falling. Expression of genes related to cell propagation was controlled under micro-gravity. Protoplast fusion of Lentinus was unaffected by micro-gravity. The mRNA fragments of gravity sensitive mutant of rice plant were affected by micro-gravity. Paramecium was set swimming in solutions with different specific gravities. The reaction behavior of Paramecium was affected by the difference in specific gravity between cell bodies and solutions. The water content metabolism functions of a mouse with needle stimulus, in particular excretory, were slightly promoted by micro- gravity. The cortisol level in blood of a falling mouse group rose showing strong stress. As the preliminary study on the geotaxis of insects, motion of bagworm was observed. 12 refs., 38 figs., 4 tabs.

  6. Economical effect of introducing a photovoltaic system on future electric power system; Shorai no denryoku keito eno taiyoko hatsuden system donyu ni yoru keizaiteki eikyo

    Energy Technology Data Exchange (ETDEWEB)

    Akata, N.; Kenmoku, Y.; Sakakibara, T. [Toyohashi University of Technology, Aichi (Japan); Kawamoto, T. [Shizuoka University, Shizuoka (Japan); Nakagawa, S. [Maizuru National College of Technology, Kyoto (Japan)

    1997-11-25

    Economic impact of introduction in the future of photovoltaic power generation (PV) systems into the commercial power system is discussed from the electric utilities` point of view. In the discussion, future demand for power is predicted from the demand for power in the base year, and the optimum power source configuration corresponding to the future demand and power generation curve are worked out by use of linear programming. Then, the fixed cost and variable cost are calculated for each of the power source components, and then the expected reduction in cost per unit of power generated is calculated. As the power sources, the hydroelectric, pumped storage, oil-fired, coal-fired, LNG-fired, combined cycle, and atomic technologies are considered. The conclusion is stated below. Upon introduction of PV power equivalent to 10% of the maximum demand power, the maximum power in the service area of Chubu Electric Power Co., Inc., will be reduced by 1.23GW in 2025, and the yearly demand power by 5472GWh. Since PV lowers the peak, an increased number of power sources low in variable cost will be used although such will be low in tracking capability. An increase in power demand will enhance the cost reducing effect of the PV system. 5 refs., 4 figs., 3 tabs.

  7. Conversion of char nitrogen to N2 under incomplete combustion conditions; Fukanzen nensho jokenka ni okeru char chuchisso no N2 eno tenka

    Energy Technology Data Exchange (ETDEWEB)

    Zhuang, Q.; Yamauchi, A.; Oshima, Y.; Wu, Z.; Otsuka, Y. [Tohoku University, Sendai (Japan). Institute for Chemical Reaction Science

    1996-10-28

    The effect of combustion conditions on conversion of char nitrogen to N2 was studied in the combustion experiment of char obtained by pyrolysis of coal. Char specimen was prepared by holding ZN coal of Chinese lignite in Ar atmosphere at 1123K for one hour. A batch scale quartz-made fluidized bed reactor was used for combustion experiment. After the specimen was fluidized in reaction gas, it was rapidly heated to start combustion reaction. CO, CO2 and N2 in produced gases were online measured by gas chromatography (GC). As the experimental result, under the incomplete combustion condition where a large amount of CO was produced by consuming almost all of O2, no NOx and N2O produced from char were found, and almost all of N-containing gas was N2. At the final stage of combustion, pyridinic-N disappeared completely, and pyrrolic-N decreased, while O-containing nitrogen complexes became a main component. It was thus suggested that O-containing nitrogen complexes are playing the role of intermediate product in combustion reaction. 7 refs., 4 figs., 1 tab.

  8. Growth hormone receptor deficiency in mice results in reduced systolic blood pressure and plasma renin, increased aortic eNOS expression, and altered cardiovascular structure and function

    DEFF Research Database (Denmark)

    Egecioglu, E; Andersson, I J; Bollano, E

    2007-01-01

    To study the role of the growth hormone receptor (GHR) in the development of cardiovascular structure and function, female GHR gene-disrupted or knockout (KO) and wild-type (WT) mice at age 18 wk were used. GHR KO mice had lower plasma renin levels (12 +/- 2 vs. 20 +/- 4 mGU/ml, P < 0.05) and inc....... These data suggest an important role for an intact GH/IGF-I axis in the maintenance of a normal cardiovascular system....

  9. Instantaneous heat flux flowing into piston top-land surface of D.I. diesel engine; DI diesel kikan no piston top land bu eno shunji netsuryusoku

    Energy Technology Data Exchange (ETDEWEB)

    Taguma, M [Zexel Corp., Tokyo (Japan); Inui, M; Enomoto, Y; Hagihara, Y [Musashi Institute of Technology, Tokyo (Japan); Koyama, T [Mitsubishi Motors Co., Tokyo (Japan)

    1997-10-01

    The thermal loads of the piston top-land surface in D.I. diesel engine during actual operation is not cleared. The authors fixed thin film thermocouples in the top-land center of a standard piston, and measured the instantaneous heat fluxes in that place. As a result, the authors made clear the thermal loads of the piston top-land surface in a cycle, and confirmed presence of the flame inflow to the piston top-land center. In addition, the authors made clear the thermal loads of the piston top-land surface in EGR operation. 4 refs., 8 figs.

  10. Sildenafil citrate-restored eNOS and PDE5 regulation in sickle cell mouse penis prevents priapism via control of oxidative/nitrosative stress.

    Science.gov (United States)

    Bivalacqua, Trinity J; Musicki, Biljana; Hsu, Lewis L; Berkowitz, Dan E; Champion, Hunter C; Burnett, Arthur L

    2013-01-01

    Sildenafil citrate revolutionized the practice of sexual medicine upon its federal regulatory agency approval approximately 15 years ago as the prototypical phosphodiesterase type 5 inhibitor indicated for the treatment of male erectile dysfunction. We now provide scientific support for its alternative use in the management of priapism, a clinical disorder of prolonged and uncontrolled penile erection. Sildenafil administered continuously to sickle cell mice, which show a priapism phenotype, reverses oxidative/nitrosative stress effects in the penis, mainly via reversion of uncoupled endothelial nitric oxide synthase to the functional coupled state of the enzyme, which in turn corrects aberrant signaling and function of the nitric oxide/cyclic GMP/protein kinase G/phosphodiesterase type 5 cascade. Priapism tendencies in these mice are reverted partially toward normal neurostimulated erection frequencies and durations after sildenafil treatment in association with normalized cyclic GMP concentration, protein kinase G activity and phosphodiesterase type 5 activity in the penis. Thus, sildenafil exerts pleiotropic effects in the penis that extend to diverse erection disorders.

  11. Study on low permeable backfill materials. Backfill materials for waste disposal facilities; Koshisuisei juten zairyo ni kansuru kenkyu. Hoshasei haikibutsu shobun shisetsu eno tekiyosei kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    Shiraishi, F; Konishi, M; Shiraishi, H [Okumura Corp., Osaka (Japan)

    1994-11-15

    A discussion was given on the fundamental properties of mortar made from cement mixed with silica fume. Four kinds of silica fumes with different particle size distributions were used. The following results were obtained: distribution of pores in mortar admixed with silica fume shifts to the smaller radius side; while the admixture increases the compression strength in mortar, the increasing trend varies depending on the kinds of silica fumes; this is thought to be caused from the difference in pozzolan activity between silica fumes; and the strength increase is caused by densification of the structure due to the pozzolan reaction that is generated after hydration, or in other words, decrease in the pore volume. The applicability of the mortar was investigated as a filling mortar to fill up clearances between wastes. It was found that the filling performance can be controlled by mixing silica fume at an adequate level and adjusting the viscosity. The diffusion coefficient for the admixed concrete is smaller by 30% to one digit than that for the ordinary concrete. High-performance water stopping concrete of 0.11 {times} 10{sup 4}cm {sup 2}/s at maximum was obtained. The concrete can be regarded as a material having superb filling and water stopping performances. 6 refs., 4 figs., 5 tabs.

  12. Economic development in India and the effect on the energy market in Asia; Indo no keizai hatten to Asia no energy shijo eno eikyo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-07-01

    As for the real GDP growth rate in India, the real GDP per capita during 1980-1993 increased 2.9% on annual average, but that in China did 8.0%. India has largely been behind China in the economic growth, but since the liberalization of economy in 1991, the Indian economy has remarkably been developed. It is predicted that the real GDP during 1993-2010 will be 5-6% on annual average. The difference in GDP increase between India and China is caused by differences in energy conservation, speed of conversion from non-commercial energy to commercial energy, serviceability of the industrial structure, etc. It is predicted that the primary energy consumption will grow on the level of China. The oil demand will grow 4-6% in China and 5-6% in India in 1993-2010, showing more increase in India. For oil import to India to exceed 1 million B/D in 2000, it is necessary to clear the ceiling of the international balance. For India to become a big country corresponding to its population size, a lot of difficulties should be overcome. 49 refs., 104 figs., 62 tabs.

  13. Management in ekonomija: ali je to dvoje ali eno? (Elementi in razumevanje postocializma in managerske revolucije = Management and Economy: Are They the Same Or Not?

    Directory of Open Access Journals (Sweden)

    Tonci Kuzmanic

    2007-03-01

    Full Text Available Author starts from important but suppressed equalisation of economy and management in post socialist and post capitalist circumstances which represents the very essence of post-modern global dominance (globalisation. An attempt to distinguish economy from management is connected with the appearance of neo-liberalism as the central argumentative machinery of management being connected with postmodern type of subjectivity. In comparison with the so-called »objective law« around which economy used to revolve (ideally, of course, management explicitly leaves this terrain and opens itself up to the subjective, even subversive activity at the level of global society. In that sense economy and management are operating on two radically different levels and we could even speak of two different entities which should be analytically distinguished. The very supposition for modern defence with regard to post-modern forms of dominance is exactly a possibility of differentiating between economy and management.

  14. ANALYSIS OF ACE, ACTN3, ENOS, PPARG, PPARA, HIF-15, PPARGC1B GENE POLYMORPHISMS FOR DETERMINATION A GENETIC PREDISPOSITION TO A VARIETY OF SPORTS

    Directory of Open Access Journals (Sweden)

    S. B. Drozdovska

    2013-05-01

    Full Text Available To establishing the possibility of assessing genetic iinherited predisposition to various sports, the differences in the distribution of genotypes of the complex polymorphisms in groups of athletes, specializing in sports with different types of energy supply of muscular work were studied. The paper examined the DNA 332 persons, of which 110 athletes involved in speed- power sports, 85 - in endurance sports , 51 - in sports that require a combination of strength and endurance, 86 - with no experience regular exercise.

  15. Field experiment for investigation of very shallow basement structure by micro-gravity survey; Microgravity tansa no gokusenbu kiban chosa eno tekiyo jikken

    Energy Technology Data Exchange (ETDEWEB)

    Oshita, K; Nozaki, K [OYO Corp., Tokyo (Japan)

    1997-10-22

    This paper illustrates the field experiment results in which micro-gravity survey was applied to investigation of very shallow basement structure between a few m and 10 m. Its applicability was discussed. In principle, the micro-gravity survey was conducted at the measuring points in a grid with 20 m pitch. Measuring points of 174 were used. The gravity system used for the measurements is an automatic gravimeter CG-3M made by the Scintrex. Survey results of P-wave reflection method conducted at the site using a vibrator focus were used as control data of micro-gravity survey. Consequently, change in the thickness of surface layer (earth filling) shallower than the depth of -10 m could be grasped as a plane. It was found that the micro-gravity survey is a useful method for the investigation of very shallow basement structure. Survey results by the reflection method could contribute to the determination of trend face at filtration and construction of density model as well as the geologic interpretation of gravity anomaly. As a result, reliability of micro-gravity survey and reflection method could be enhanced, mutually. 3 refs., 8 figs.

  16. Study on application of radar technique to explore mineral resources. 1. Sample test in laboratory; Radar ho no kosho tansa eno tekiyosei kento. 1. Shitsunai shiryo shiken

    Energy Technology Data Exchange (ETDEWEB)

    Chiba, A; Okada, K [Sumitomo Metal Mining Co. Ltd., Tokyo (Japan); Arai, E [Metal Mining Agency of Japan, Tokyo (Japan); Noguchi, K; Fujiwara, K [Waseda University, Tokyo (Japan)

    1997-10-22

    Dielectric constants of ore body and mother rock specimens taken from an epithermal gold deposit were measured in the frequency band of radar technique. Applicability of the radar technique to mineral exploration has been investigated by comparing measured results and ore showing. This paper describes the results. Measured results of the dielectric constants are summarized as follows. The specific dielectric constant in the forced dry condition did not depend on specimens. The specific dielectric constant in the water saturated condition increased with increasing the porosity. The conductivity increased with increasing the specific dielectric constant. The specific dielectric constant and conductivity increased with increasing the water content. The specific dielectric constant did not depend on types of rocks. The specific dielectric constant decreased with increasing the frequency. Difference of the specific dielectric constant in the water saturated condition decreased with increasing the frequency. The radar technique was applied to blind deposits. Since they were often in the ground water saturated zones, it was considered that the reflection at the boundary was enhanced with increasing the difference of specific dielectric constant between ore body and mother rock compared with that in unsaturated zones. 8 refs., 8 figs., 3 tabs.

  17. Simulation of emergency evacuation behaviour during disaster by using distinct element method; Hisaiji no gunshu hinan kodo simulation eno kobetsu yosoho no tekiyo ni tsuite

    Energy Technology Data Exchange (ETDEWEB)

    Kiyono, J.; Miura, F.; Takimoto, K. [Yamaguchi Univ., Yamaguchi (Japan). Faculty of Engineering

    1996-04-21

    In this study, the possibility to apply the Distinct Element Method (DEM) to human evacuation behavior during a disaster was investigated, evacuation from rooms to outside though a passage or steps and a jam were examined as a basic consideration. The main results were obtained as follows: according to an analysis of evacuation behavior when elements of DEM were substituted for individual humans, the trace of individual people and force acting there to and the trace of the whole group so every time can be understood, analysis can also be conducted from local to macro. In the DEM analysis, a mutual distance between people and characteristics of behavior can be expressed well by introducing an imaginary bane into the elements. Evacuation time due to change of space shape can be compared and time series change of force acting on individual people can be understood according to the investigation on evacuation time difference due to shape change at the exit and entrance and the jam caused by the arch effect happened when the crowed flow appeared at the exit and entrance. 16 refs., 21 figs., 4 tabs.

  18. Sildenafil citrate-restored eNOS and PDE5 regulation in sickle cell mouse penis prevents priapism via control of oxidative/nitrosative stress.

    Directory of Open Access Journals (Sweden)

    Trinity J Bivalacqua

    Full Text Available Sildenafil citrate revolutionized the practice of sexual medicine upon its federal regulatory agency approval approximately 15 years ago as the prototypical phosphodiesterase type 5 inhibitor indicated for the treatment of male erectile dysfunction. We now provide scientific support for its alternative use in the management of priapism, a clinical disorder of prolonged and uncontrolled penile erection. Sildenafil administered continuously to sickle cell mice, which show a priapism phenotype, reverses oxidative/nitrosative stress effects in the penis, mainly via reversion of uncoupled endothelial nitric oxide synthase to the functional coupled state of the enzyme, which in turn corrects aberrant signaling and function of the nitric oxide/cyclic GMP/protein kinase G/phosphodiesterase type 5 cascade. Priapism tendencies in these mice are reverted partially toward normal neurostimulated erection frequencies and durations after sildenafil treatment in association with normalized cyclic GMP concentration, protein kinase G activity and phosphodiesterase type 5 activity in the penis. Thus, sildenafil exerts pleiotropic effects in the penis that extend to diverse erection disorders.

  19. Sočutno starševstvo in vzgojni stili v eno- in dvostarševski družini

    OpenAIRE

    Novak, Petra; Urh, Katarina; Presker, Martina

    2018-01-01

    Vzgoja otroka je ena izmed najtežjih vsebin življenja, v katero so starši neposredno vpleteni v procesu svojega delovanja. Otrok se rodi v že ustaljen sistem, ki si ga zakonca oziroma partnerja ustvarita še pred rojstvom otroka. Z vsakim novorojenim otrokom je treba vzpostaviti novo družinsko ravnovesje, da se bo družina lahko razvijala naprej. Pri razvoju otroka v družini ima najpomembnejšo vlogo odnos, ki ga starša vzpostavita z njim takoj ob njegovem rojstvu. Enako pomembno je tudi čustven...

  20. Všeobecný přenos daňové povinnosti jako krok k zásadní modernizaci DPH

    OpenAIRE

    Kohoutková, Růžena

    2014-01-01

    This final thesis deals with introduction of reverse charge mechanism of value added tax. The current system of value added tax has weaknesses, including carousel fraud, negative impact on cash flow of businesses and complicated rules to collect and manage the tax. Reverse charge mechanism is considered as a solution of existing weaknesses of current system. Although this regime is able to solve the mentioned weaknesses, it also has some disadvantages. Especially, it is a negative impact on c...

  1. Material revolution, and analysis of its impacts on the industry and technology of the next generation; Zairyo kakumei to jisedai sangyo gijutsu eno impact bunseki

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1984-03-01

    This paper discusses possibility of advanced materials from seeds and expectations from needs; and also describes consistency between the seeds and needs, and possible impacts of these materials on the industry and technology of the next generation. Chapter 1 presents the promising results and eventual possibilities, based on the basic studies, of the advanced materials, e.g., fine ceramics, highly functional polymers, new alloys and composite materials. Chapter 2 analyzes the properties and functions attainable by these materials, and expected applicable areas; investigates their technical and economical possibilities; and also investigates their ripple effects on the technology and economy. Chapter 3 investigates the current situations of the demands in the automobile, chemical plant and energy areas, and problems involved in development of these materials for these areas. Chapter 4 investigates the measures to promote consistency between the seeds and needs of these materials, and impacts of these advanced materials on the related techniques, related industries and industrial structures. Chapter 5 summarizes the problems and measures narrowed down in Chapters 1 to 4 comprehensively for the above areas; and the measures to be taken by the private sector, and cooperation by the industrial, government and academic circles. (NEDO)

  2. In Vitro Activation of eNOS by Mangifera indica (Careless™) and Determination of an Effective Dosage in a Randomized, Double-Blind, Human Pilot Study on Microcirculation.

    Science.gov (United States)

    Gerstgrasser, Alexandra; Röchter, Sigrid; Dressler, Dirk; Schön, Christiane; Reule, Claudia; Buchwald-Werner, Sybille

    2016-03-01

    Mangifera indica fruit preparation (Careless™) activates the evolutionary conserved metabolic sensors sirtuin 1 and adenosine monophosphate-activated protein kinase, which have been identified as playing a key role in microcirculation and endothelial function. Here, an acute effect of a single dose of 100 mg or 300 mg Careless™ on microcirculation was investigated in a randomized, double-blind, crossover pilot study in ten healthy women to determine the effective dosage. Microcirculation and endothelial function were assessed by the Oxygen-to-see system and pulse amplitude tonometry (EndoPAT™), respectively. Cutaneous blood flow was increased over time by 100 mg (54% over pre-values, p = 0.0157) and 300 mg (35% over pre-value, p = 0.209) Careless™. The EndoPAT™ reactive hyperemia response was slightly improved 3 h after intake compared to pretesting with 300 mg Careless™. Furthermore, activation of endothelial nitric oxide synthase, as an important regulator for endothelial function, was tested in vitro in primary human umbilical vein endothelial cells. Careless™, after simulation of digestion, increased the activated form of endothelial nitric oxide synthase dose-dependently by 23% (300 µg/mL), 42% (1500 µg/mL), and 60% (3000 µg/mL) compared to the untreated control. In conclusion, the study suggests moderate beneficial effects of Careless™ on microcirculation, which is at least partly mediated by endothelial nitric oxide synthase activation. Georg Thieme Verlag KG Stuttgart · New York.

  3. Effects of fuel properties and oxidation catalyst on diesel exhaust emissions; Keiyu seijo oyobi sanka shokubai no diesel haishutsu gas eno eikyo

    Energy Technology Data Exchange (ETDEWEB)

    Aihara, S; Morihisa, H; Tamanouchi, M; Araki, H; Yamada, S [Petroleum Energy Center, Advanced Technology and Research Institute, Tokyo (Japan)

    1997-10-01

    Effects of fuel properties (T90 and Poly-Aromatic Hydrocarbons: PAH) and oxidation catalyst on diesel exhaust emissions were studied using three DI diesel engines and two diesel passenger cars. (IDI engine) PM emissions were found to increase as T90 and PAH increased and could be decreased considerably for each fuel if an oxidation catalyst was installed. 5 refs., 9 figs., 3 tabs.

  4. Simple method for thick blade calculation. Part 2. Application to a thin blade; Kanbenna ichiatsuyoku keisanho (zokuho). Usui tsubasa eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Maita, S; Ando, J; Nakatake, K [Kyushu University, Fukuoka (Japan). Faculty of Engineering

    1996-04-10

    A source and QCM (SQCM) method has been developed, by which the blade performance can be calculated in a short time with satisfying the Kutta`s condition without repeating calculations even for the three-dimensional blade. Performances were calculated for the two-dimensional and three-dimensional blades. The SQCM has provided appropriate results. However, it was found that there are some problems for thin blades. In this study, the SQCM has been applied to a thin blade. The conventional eddy model equation of SQCM is not a continuous distribution in the strict sense. In this study, this problem has been modified. When point eddies with constant strength are in line continuously within the interval, the induced velocity at an arbitrary position can be expressed by the integral equation using a position of marginal point of the interval. This equation can be analyzed by the integral of influence coefficient. The position of marginal point of the interval is a position of control point determined by the QCM theory. As a result of the modification, it was found that the SQCM in response to a thin blade has provided precise calculation results stably even for an ultra thin blade with the blade thickness ratio of 0.001. 1 ref., 8 figs.

  5. Application of vertical electrical sounding combined with induced polarization method in ground water exploration; IP koka wo koryoshita hiteikoho suichoku tansa no chikasui chosa eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Kondo, M; Sakurada, H [Sumiko Consultants Co. Ltd., Tokyo (Japan); Suzuki, T [Hokkaido Development Bureau, Hokkaido Development Agency, Sapporo (Japan)

    1996-10-01

    For ground water exploration using vertical Schlumberger exploration method, measurement and analysis combined with induced polarization (IP) effect were conducted as trial. For the Schlumberger method, potential is measured at the center between potential electrodes during flow of dc current between current electrodes. In the case of vertical exploration, measurements are repeated with fixed potential electrodes by extending the distance between current electrodes. Ground water exploration was conducted using this method at Otaki village, Hokkaido. Geology of surveyed plateau consists of a basement of Pliocene tuffs and Quaternary Pleistocene sediments covering on the surface. For the results of analysis, four to seven beds were detected from the resistivity. The depth up to the lowest bed was between 25 and 85 m, the resistivity of each bed was between 9 and 8,000 ohm{times}m, and the polarizability was between 1 and 15 mV/V. Among these resistivity zones, it was judged that zones satisfying following three conditions correspond to coarse grain sediments saturated with ground water, and can be expected as aquifers; having resistivity ranging between 100 and 1,000 ohm{times}m, polarizability higher than 10 mV/V, and relatively large thickness. 11 refs., 6 figs.

  6. Three dimensional transient electromagnetic model study for fracture prediction from tunnel face; Sanjigen model keisan ni yoru TEM ho no tunnel zenpo tansa eno tekiyosei no kento

    Energy Technology Data Exchange (ETDEWEB)

    Wada, K; Tsutsui, T; Saito, A [Mitsui Mineral Development Engineering Co. Ltd., Tokyo (Japan); Hara, T [Toda Corp., Tokyo, (Japan); Zhdanov, M [University of Utah, UT (United States)

    1996-10-01

    In order to apply TEM model to fracture prediction at tunnel face, 3-D TEM model computation by FEM was conducted by installing a transmission loop on a tunnel face. MT field responses diffusing into the 3-D model were computed by time-domain difference calculus, and analytical precision was improved by introducing a staggered grid method. In the case where a low resistive zone exists before a tunnel face, time variance in diffused eddy current and induction current in the low resistive zone could be obtained. The difference in tunnel-axial transient curve (transient phenomenon curve in magnetic field) between uniform medium and low resistive zone models was based on the absorption process of diffused eddy current into the low resistive zone, and the expanding process of it toward the outside. Change in background condition could be predicted from the background and the ratio of transient curves every measurement. The detection limit of the low resistive zone was dependent on resistivity contrast, distance and geometry. Fluctuation in measurement due to noises and S/N ratio were also essential. 3 refs., 10 figs.

  7. Can spatial autocorrelation method be applied to arbitrary array shape; Kukan jiko sokanho no nin`i array eno tekiyo kanosei

    Energy Technology Data Exchange (ETDEWEB)

    Yamamoto, H; Iwamoto, K; Saito, T; Tachibana, M [Iwate University, Iwate (Japan). Faculty of Engineering

    1997-05-27

    Methods to learn underground structures by utilizing the dispersion phenomenon of surface waves contained in microtremors include the frequency-wave number analysis method (the F-K method) and the spatial autocorrelation method (the SAC method). Despite the fact that the SAC method is capable of exploring structures at greater depths, the method is not utilized because of its stringent restriction in arrangement of seismometers during observation that they must be arranged evenly on the same circumference. In order to eliminate this restriction in the SAC method, a research group in the Hokuriku University has proposed an expanded spatial autocorrelation (ESAC) method. Using the concept of the ESAC method as its base, a method was realized to improve phase velocity estimation by making a simulation on an array shifted to the radius direction. As a result of the discussion, it was found that the proposed improvement method can be applied to places where waves come from a number of directions, such as urban areas. If the improvement method can be applied, the spatial autocorrelation function needs not be even in the circumferential direction. In other words, the SAC method can be applied to arbitrary arrays. 1 ref., 7 figs.

  8. Passive leg movement enhances interstitial VEGF protein, endothelial cell proliferation, and eNOS mRNA content in human skeletal muscle

    DEFF Research Database (Denmark)

    Hellsten, Ylva; Rufener, Nora; Nielsen, Jens J

    2008-01-01

    .05) in blood flow without a significant enhancement in oxygen uptake. Muscle interstitial fluid was sampled with microdialysis technique and analyzed for vascular endothelial growth factor (VEGF) protein and for the effect on endothelial cell proliferation. Biopsies obtained from the musculus vastus lateralis...... to cultured endothelial cells revealed that dialysate obtained during leg movement induced a 3.2-fold higher proliferation rate (P level fourfold above resting levels. VEGF mRNA and MMP-2 mRNA levels were...

  9. Utilization of hot exhaust water from power station to marine cultivation to increase product. Hatsudensho onhaisui no suisan zoyoshoku eno riyo

    Energy Technology Data Exchange (ETDEWEB)

    Chiba, K [The University of Tokyo, Tokyo (Japan). Faculty of Agriculture

    1990-07-20

    A large quantity of waste sea water, exhausted after having been used as cooling water in the thermal and unclear power stations, is higher by about 7 centigrade in temperature than that when taken in. Its utilization to the marine cultivation to increase product was explained in present status and points of problem. Among aquatic animals to like high temperature, those, valuavle from the viewpoint of fishery, are bred in different places. Upon breeding spawn to fry young fish, there are two methods of using it, ie., as species to be cultivated or let go in the water flow, and for the production of edible fish, high in price, such as sea bream, yellowtail and lobster. In any case, hot exhaust water gives effect of having fish quickly grow, and stimulating spawn and fry young fish in sexual ripeness. For example, ear shell and prawn are 5 to 6 times in elongation of shell length and 9 times even in weight, respectively, as large as those in case of natural sea water. While there are problems in costing required for pumping hot exhaust water up in the cultivation on land, and temperature adjustment in summer and winter, and water quality control in the crawl cultivation at the water takeout, which must be going to be solved for the commercialization and industrialization. 10 figs., 1 tab.

  10. FY 2000 report on the survey of strategies for spreading renewable energy to developing countries; 2000 nendo tojokoku eno saisei kano energy fukyu senryaku chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    For Laos, Bangladesh, Malaysia and Vietnam, survey was conducted to promote the introduction and spread of renewable energy, mainly the photovoltaic power generation. Relating to the solar radiation, the amount in the four countries is much higher than that in Japan, 3.4kWh/m{sup 2}/day on average. The countries are areas suitable for the photovoltaic power generation. As to the wind velocity, the area where the wind velocity is higher than 5m/second, which enables the introduction of the wind power generation, is limited to the south/west of Bangladesh, Malaysia, and the coastal part and islands in Vietnam. The wind power generation is being used in Malaysia and Vietnam. As for the precipitation, it rains concentratedly in the rainy season, and therefore, it is difficult to stably secure energy through the year by the small-scale hydroelectric power generation. In Vietnam, however, resident individuals eagerly introduce the small-scale hydroelectric power generation, and about 20,000kW is now in operation. Concerning the introduction of the photovoltaic power generation, Bangladesh is in a state of working out a master plan, Laos is in a state of drawing up a plan for the spread, and Malaysia and Vietnam are in a state of the verification. (NEDO)

  11. Fundamental study on PV system for floating water power device `Mighty Whale`; Okiai futaishiki haryoku sochi `Mighty Whale` eno taiyoko hatsuden sochi tosai no kihon kento

    Energy Technology Data Exchange (ETDEWEB)

    Washio, Y [Japan Marine Science and Technology Center, Kanagawa (Japan)

    1996-10-27

    Studied in this paper is the use of a photovoltaic power generation system in combination with a wave energy conversion system to cover the latter`s weak point that it is available but intermittently. An offshore floating wave power device Mighty Whale (MW) is described, which will have a wave energy absorbing air chamber in the front and an anti-rocking float that looks like a whale in the rear. The movement, up and down and back and forth, of the water surface in the air chamber due to incident waves turns the power generator turbine. Out of the space available on the MW, a 200m{sup 2} area has been specified as the place suitable for the installation of solar cells capable of a maximum output of 20kW, for which specification the elevation of the sun has been taken into account. Batteries will routinely be supplied with power in parallel from the wave activated and photovoltaic devices, the supply will be limited when the batteries are fully charged, and an auxiliary power generator will be run in case of shortage. Power that can be provided by a 20kW solar array was calculated using actual data of sunshine on the slope for each array orientation, and required battery capacity was calculated for each solar array orientation. Important items for consideration for the insurance of reliability on the ocean include measures against salt damage, detailed designing of wiring, and coordinated operation of photovoltaic and wave activated power generation systems. 3 refs., 6 figs., 5 tabs.

  12. Thermal sensation vote simulation on the aged for bus air conditioning; Koreisha wo koryoshita onkan suchi simulation no bus kucho eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Takeuchi, H; Nishijima, H; Kitada, M; Shinma, A [Denso Corp., Aichi (Japan)

    1997-10-01

    The Numbers of passengers on the aged of sight-seeing buses about 5 times bigger than those of car passengers, have been increasing gradually. The former paper of DENSO in 1994 introduces quantitative method, which simulates passenger heat amount given by sun light at various solar positions. At this time, this paper introduces quantitative method, which simulates passengers thermal sensation skin temperature and also heat amount given by sun light at various solar positions. 5 refs., 8 figs., 2 tabs.

  13. Psychological influences for the driver by the changes of running circumstance; Jidosha no soko kankyo henka no driver eno shinriteki eikyo

    Energy Technology Data Exchange (ETDEWEB)

    Okura, S; Yokomori, M; Yamaguchi, S [Meijo University, Nagoya (Japan)

    1997-10-01

    A driver is influenced psychologically by the cars proceeding on the street and the cars parked on the shoulder which come into the front view. The traffic accidents are caused when these influences put a lot of stress on a driver. In this report, we study the relations between the road traffic condition on the streets and the highway and the driver`s psychological and psysiological responses by using the driver`s front view, sweating and pulse rate. 6 refs., 8 figs.

  14. Estrogen and phytoestrogens: Effect on eNOS expression and in vitro vasodilation in cerebral arteries in ovariectomized Watanabe heritable hyperlipidemic rabbits

    DEFF Research Database (Denmark)

    Lund, Claus Otto; Mortensen, A; Nilas, Lisbeth

    2007-01-01

    -six female ovariectomized Watanabe heritable hyperlipidemic (WHHL) rabbits were randomised to treatment with 17beta-estradiol (17beta-E(2)), SoyLife 150 or control for 16 weeks. Ring segments of basilar artery (BA) and posterior cerebral artery (PCA) were mounted in myographs for isometric tension recordings...

  15. Recent progress in 'bioelectronics' research. Part 4. ; Recent trends in biosensor research and development. Baioerekutoronikusu eno michi (shorai wa saibogu mo). 4. ; Baiosensa gijutsu saizensen

    Energy Technology Data Exchange (ETDEWEB)

    Karube, I. (The Univ. of Tokyo, Tokyo (Japan). Research Center for Advanced Science and Technology)

    1994-02-20

    Biosensors are structured basing on a variety of principles. The latest trend of the research and development of biosensors is introduced to explain how the five senses such as taste sense and olfactory sense are detected. A biosensor is structured by combining biological element with a transducer which converts the result measured by the said element into electrical signal. Enzyme is most widely used at present. The enzyme recognizes a chemical substance very closely, and has a feature of promoting its reaction only. Chemical substances, therefore, can be distinguished if this enzyme is used. The principle of the biosensor is explained quoting the enzyme sensor as an example. Immune reaction and microbe reaction can be monitored by the similar principle to the above-mentioned principle. Sensors for measuring substances which are the bases of taste have been developed. Studies on smell sensors are also actively carried on, and the quartz oscillator is used mainly. 4 refs., 4 figs.

  16. Advancing aging society and its effect on the residential use energy demand; Shintensuru koreika shakai to kateiyo energy juyo eno eikyo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-07-01

    The paper analyzed various factors regulating the energy demand in aged households and viewed the future residential use energy demand in the aging society. In Part 1, based on the family budget survey annual report, a study was made of the energy consumption situation of aged people and the trend of the future residential energy consumption. In Part 2, a study was conducted based on survey data on the U.K., France, Sweden and Denmark. In Western countries which are the developed countries of aging, the energy conservation policy effectively worked for the space heating demand which is highest of all, and factors of the energy consumption increase by aging were absorbed. However, since in Japan, aging is rapidly advancing and further there are relatively more factors which connect to an increase in energy consumption in aged households as compared with Western countries, it is thought that Japan is in a situation where the energy consumption increases more often, influenced by aged households. 91 refs., 130 figs., 41 tabs.

  17. FY 1990 achievement report on the survey of possibility of introducing solar energy into buildings; 1990 nendo taiyo energy no kenchikubutsu eno donyu kanosei chosa seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1991-03-01

    This paper describes the achievements in fiscal 1990 on survey on possibility of introducing solar energy into buildings. Capacity of photovoltaic power generation facilities installed on an area of 1600 km{sup 2}, such as roofs of residential houses, schools and building may be calculated on a trial bases as 100 million kW at maximum. The capacity can replace 16% of the total demand and corresponds to 26.30 million kiloliters (9%) as converted to crude oil. If photovoltaic power generation is utilized on buildings of users, diversified technological criteria are required from the viewpoint of legislation covering wide range of architectural, electrical and disaster aspects. However, no direct and clear standards are available now, except for the electric power business law. What are urgently required are solar cell standardization, incentive subsidies, aging safety, institutions for electric power sale and purchase, and establishment of technological criteria. An utilization example survey revealed problems in array installation and size. Increased demand, mass production and cost reduction will create a favorable cycle. Introduction, proliferation, and acceleration under policies at public facilities which are expected of enlightenment and development into other areas will be the effective means for the purpose. (NEDO)

  18. Application of super workable concrete to main tower of cable-stayed prestressed concrete bridge. ; Kiba park grand bridge. PC shachokyo no shuto eno tekiyo. ; Kiba koen ohashi

    Energy Technology Data Exchange (ETDEWEB)

    Matsuoka, Y.; Shindo, T.; Sakamoto, A. (Taisei Corp., Tokyo (Japan))

    1993-08-01

    The Kiba Park Grand Bridge is a cable-stayed prestressed concrete (PC) bridge with a length of 186m. The main tower of this PC cable-stayed bridge consists of a pair of vertical columns with height of 60m and a beam connecting the columns. For the purpose of the advanced efficiency of construction without formwork and removal work and the improvement of durability, the precast buried formwork made of polymer impregnated concrete formwork was adopted. Approximate 650 cubic meter of super workable concrete was placed for the upper part ranging from 7th to 17th blocks of vertical columns and the beam. Blast furnace cement B and fly ash were used as binder. Naphthalenesulfonic acid type high performance water reducing agent and lignosulfonic acid type AE (air-entraining) water reducing agent were used as admixtures. Super workable concrete was mixed using forced double-axle mixers in the ready-mixed concrete plant. Satisfactory quality of the fresh concrete and strength of the hardened concrete were obtained. 2 refs., 11 figs., 3 tabs.

  19. Progress of admixtures and quality of concrete. 2. ; Approaches to ultra-high-strength concrete. Konwa zairyo no shinpo to concrete no hinshitsu. 2. ; Chokokyodo concrete eno approach

    Energy Technology Data Exchange (ETDEWEB)

    Kawai, T. (Shimizu Construction Co. Ltd., Tokyo (Japan)); Abe, M. (Building Research Institute, Tsukuba (Japan))

    1994-02-15

    Ultra-high-strength concrete of 600 kgf/cm[sup 2] or more is reviewed. MDF (macro defect free) cement, spheroidal cement and mechanically stabilized cement have been developed for ultra-high-strength concrete, however, in general, DSP (densified system containing homogeneously arranged ultra-fine particles) technique is now usual in which a water-cement ratio is reduced by use of advanced air entraining and water reducing agents and cured concrete is densified by use of ultra-fine particles as admixture. Four kinds of substances such as naphthalene system and polycarboxylic acid system are used as air entraining and water reducing agents, and silica fume is used as ultra-fine particle admixture which can be effectively replaced with blast furnace slag or fly ash. Various use examples of ultra-high-strength concrete such as an ocean platform are found in the world, however, only some examples such as a PC truss bridge and the main tower of a PC cable stayed bridge in Japan. 22 refs., 10 figs., 2 tabs.

  20. Deposition of calcium carbonate into postglacial reefs: a test on a 'coral reef hypothesis'. Kohyoki no sangosho eno tansan calcium taiseki sokudo

    Energy Technology Data Exchange (ETDEWEB)

    Kayanne, H [Geological Survey of Japan, Tsukuba (Japan)

    1993-06-15

    This paper describes the following matters on changes in rates of deposition of calcium carbonate into postglacial coral reefs: Estimation was made on change in CaCO3 deposition in four coral reefs the data of which relating to all cross sections down to reef base have been acquired by drilling; the main deposition periods in the coral reefs formed in the postglacial period were five to six thousand years ago; the maximum deposition rate is estimated to be 2.7 [times] 10[sup 14] gC per one thousand years under an assumption that the total deposition amount in postglacial coral reefs is 1.2 [times] 10[sup 18] gC (converted to carbon amount); the recent deposition rate is (1/7.5) that of the former rate; from information obtained on submerged coral reefs, deposition amounts in coral reefs before 10,000 years ago are judged to have been smaller than those thereafter; and the above knowledges do not support the 'coral reef hypothesis' by Berger et al. that deposition of calcium carbonate into postglacial coral reefs has occurred from 15,000 years ago to 10,000 years ago. 30 refs., 2 figs.