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Sample records for kai saks elmut

  1. Loop-Loop Interactions Regulate KaiA-Stimulated KaiC Phosphorylation in the Cyanobacterial KaiABC Circadian Clock

    Energy Technology Data Exchange (ETDEWEB)

    Egli, Martin [Vanderbilt Univ., Nashville, TN (United States); Pattanayek, Rekha [Vanderbilt Univ., Nashville, TN (United States); Sheehan, Jonathan H. [Vanderbilt Univ., Nashville, TN (United States); Xu, Yao [Vanderbilt Univ., Nashville, TN (United States); Mori, Tetsuya [Vanderbilt Univ., Nashville, TN (United States); Smith, Jarrod A. [Vanderbilt Univ., Nashville, TN (United States); Johnson, Carl H. [Vanderbilt Univ., Nashville, TN (United States)

    2013-01-25

    We found that the Synechococcus elongatus KaiA, KaiB, and KaiC proteins in the presence of ATP generate a post-translational oscillator that runs in a temperature-compensated manner with a period of 24 h. KaiA dimer stimulates phosphorylation of KaiC hexamer at two sites per subunit, T432 and S431, and KaiB dimers antagonize KaiA action and induce KaiC subunit exchange. Neither the mechanism of KaiA-stimulated KaiC phosphorylation nor that of KaiB-mediated KaiC dephosphorylation is understood in detail at present. We demonstrate here that the A422V KaiC mutant sheds light on the former mechanism. It was previously reported that A422V is less sensitive to dark pulse-induced phase resetting and has a reduced amplitude of the KaiC phosphorylation rhythm in vivo. A422 maps to a loop (422-loop) that continues toward the phosphorylation sites. By pulling on the C-terminal peptide of KaiC (A-loop), KaiA removes restraints from the adjacent 422-loop whose increased flexibility indirectly promotes kinase activity. We found in the crystal structure that A422V KaiC lacks phosphorylation at S431 and exhibits a subtle, local conformational change relative to wild-type KaiC. Molecular dynamics simulations indicate higher mobility of the 422-loop in the absence of the A-loop and mobility differences in other areas associated with phosphorylation activity between wild-type and mutant KaiCs. Finally, the A-loop–422-loop relay that informs KaiC phosphorylation sites of KaiA dimer binding propagates to loops from neighboring KaiC subunits, thus providing support for a concerted allosteric mechanism of phosphorylation.

  2. CryoEM and Molecular Dynamics of the Circadian KaiB-KaiC Complex Indicates That KaiB Monomers Interact with KaiC and Block ATP Binding Clefts

    Energy Technology Data Exchange (ETDEWEB)

    Villarreal, Seth A.; Pattanayek, Rekha; Williams, Dewight R.; Mori, Tetsuya; Qin, Ximing; Johnson, Carl H.; Egli, Martin; Stewart, Phoebe L. [Case Western; (Vanderbilt); (Vanderbilt-MED)

    2014-10-02

    The circadian control of cellular processes in cyanobacteria is regulated by a posttranslational oscillator formed by three Kai proteins. During the oscillator cycle, KaiA serves to promote autophosphorylation of KaiC while KaiB counteracts this effect. Here, we present a crystallographic structure of the wild-type Synechococcus elongatus KaiB and a cryo-electron microscopy (cryoEM) structure of a KaiBC complex. The crystal structure shows the expected dimer core structure and significant conformational variations of the KaiB C-terminal region, which is functionally important in maintaining rhythmicity. The KaiBC sample was formed with a C-terminally truncated form of KaiC, KaiC-Δ489, which is persistently phosphorylated. The KaiB–KaiC-Δ489 structure reveals that the KaiC hexamer can bind six monomers of KaiB, which form a continuous ring of density in the KaiBC complex. We performed cryoEM-guided molecular dynamics flexible fitting simulations with crystal structures of KaiB and KaiC to probe the KaiBC protein–protein interface. This analysis indicated a favorable binding mode for the KaiB monomer on the CII end of KaiC, involving two adjacent KaiC subunits and spanning an ATP binding cleft. A KaiC mutation, R468C, which has been shown to affect the affinity of KaiB for KaiC and lengthen the period in a bioluminescence rhythm assay, is found within the middle of the predicted KaiBC interface. The proposed KaiB binding mode blocks access to the ATP binding cleft in the CII ring of KaiC, which provides insight into how KaiB might influence the phosphorylation status of KaiC.

  3. An evaluation of sex-age-kill (SAK) model performance

    Science.gov (United States)

    Millspaugh, Joshua J.; Skalski, John R.; Townsend, Richard L.; Diefenbach, Duane R.; Boyce, Mark S.; Hansen, Lonnie P.; Kammermeyer, Kent

    2009-01-01

    The sex-age-kill (SAK) model is widely used to estimate abundance of harvested large mammals, including white-tailed deer (Odocoileus virginianus). Despite a long history of use, few formal evaluations of SAK performance exist. We investigated how violations of the stable age distribution and stationary population assumption, changes to male or female harvest, stochastic effects (i.e., random fluctuations in recruitment and survival), and sampling efforts influenced SAK estimation. When the simulated population had a stable age distribution and λ > 1, the SAK model underestimated abundance. Conversely, when λ < 1, the SAK overestimated abundance. When changes to male harvest were introduced, SAK estimates were opposite the true population trend. In contrast, SAK estimates were robust to changes in female harvest rates. Stochastic effects caused SAK estimates to fluctuate about their equilibrium abundance, but the effect dampened as the size of the surveyed population increased. When we considered both stochastic effects and sampling error at a deer management unit scale the resultant abundance estimates were within ±121.9% of the true population level 95% of the time. These combined results demonstrate extreme sensitivity to model violations and scale of analysis. Without changes to model formulation, the SAK model will be biased when λ ≠ 1. Furthermore, any factor that alters the male harvest rate, such as changes to regulations or changes in hunter attitudes, will bias population estimates. Sex-age-kill estimates may be precise at large spatial scales, such as the state level, but less so at the individual management unit level. Alternative models, such as statistical age-at-harvest models, which require similar data types, might allow for more robust, broad-scale demographic assessments.

  4. Study on preservation of sweet apricot kernel (SAK) by γ-irradiation

    International Nuclear Information System (INIS)

    Wang Jide; Xu Fang

    1992-01-01

    This paper introduces the study on effect of insecticide and sterilization of SAK by 60 Co γ irradiation. The results declare that the proper dose kill the insect eggs on the surface of SAK is 3.5 kGy, the preserving period under ambient temperature is up to 7 months, the intactness rate is 100%, and the SAK can be safely stored through the summer. By the irradiation of 3.5 kGy, the sanitary quality of SAK can be notably improved and the amount of microbes can decrease by at least 99%. There are no remarkable changes of the main nutrition components of irradiated SAK

  5. Kai õpetab iseennast / Kai Kaljo ; intervjueerinud R[eet] V[arblane

    Index Scriptorium Estoniae

    Kaljo, Kai, 1959-

    2011-01-01

    Kai Kaljo isikunäitus "Kai õpetab iseennast" Hobusepea galeriis 2.-14. novembrini 2011. Kaks videot seostuvad Kai Kaljo õppejõutööga Tallinna Ülikoolis, ka kaasaegse kunsti professori ametist Tallinna Ülikooli kunstihariduse osakonnas. Näitusel osale külalisesinejana Austraalia kirjanik Luke Davies, näitusel oli tema lühifilm "Õhk"

  6. Survey of Two New (Kai 1 and Kai 2) and Other Blood Groups in Dogs of North America.

    Science.gov (United States)

    Euler, C C; Lee, J H; Kim, H Y; Raj, K; Mizukami, K; Giger, U

    2016-09-01

    Based upon serology, >10 canine blood group systems have been reported. We surveyed dogs for dog erythrocyte antigen (DEA) 1 and 2 new blood types (Kai 1 and Kai 2), and some samples also were screened for Dal and DEA 3, 4, and 7. Blood samples provided by owners, breeders, animal blood banks, and clinical laboratories were typed for DEA 1 by an immunochromatographic strip technique with a monoclonal antibody and analysis of band intensity. Both new antigens, the Dal and other DEAs (except DEA 7 by tube method), were assessed by a gel column method with either monoclonal or polyclonal antibodies. The same gel column method was applied for alloantibody detection. Of 503 dogs typed, 59.6% were DEA 1+ with 4% weakly, 10% moderately, and 45.6% strongly DEA 1+. Regarding Kai 1 and Kai 2, 94% were Kai 1+/Kai 2-, 5% were Kai 1-/Kai 2- and 1% were Kai 1-/Kai 2+, but none were Kai 1+/Kai 2+. There was no relationship between Kai 1/Kai 2 and other blood types tested. Plasma from DEA 1-, Kai 1-, Kai 2- dogs, or some combination of these contained no detectable alloantibodies against DEA 1 and Kai 1 or Kai, respectively. The new blood types, called Kai 1 and Kai 2, are unrelated to DEA 1, 3, 4, and 7 and Dal. Kai 1+/Kai 2- dogs were most commonly found in North America. The clinical relevance of Kai 1 and Kai 2 in canine transfusion medicine still needs to be elucidated. Copyright © 2016 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.

  7. New derivative of staphylokinase SAK-RGD-K2-Hirul exerts thrombolytic effects in the arterial thrombosis model in rats.

    Science.gov (United States)

    Szemraj, Janusz; Zakrzeska, Agnieszka; Brown, George; Stankiewicz, Adrian; Gromotowicz, Anna; Grędziński, Tomasz; Chabielska, Ewa

    2011-01-01

    SAK-RGD-K2-Hir and SAK-RGD-K2-Hirul are recombinant proteins that are derivatives of r-SAK (recombinant staphylokinase). They are characterized by their fibrin-specific plasminogen activation properties and their antithrombin and antiplatelet activities. The difference between these proteins is the presence of the antithrombotic fragment (hirudin or hirulog) in the C-terminal portion of the r-SAK. The aim of the present study was to examine the thrombolytic potentials of SAK-RGD-K2-Hir and SAK-RGD-K2-Hirul in an electrically induced carotid artery thrombosis model in rats and to compare the potentials to that of r-SAK. We determined that a bolus injection of SAK-RGD-K2-Hirul was more effective than one of r-SAK in the improvement and maintenance of carotid patency and in arterial thrombus weight reduction; however, it had the same potency as SAK-RGD-K2-Hir. The bleeding time, prothrombin time and activated partial thromboplastin time were significantly prolonged in the animals that were treated with either dose (1.5 or 3.0 mg/kg) of SAK-RGD-K2-Hir or SAK-RGD-K2-Hirul, whereas no changes were observed in the plasma fibrinogen concentration or the α2 plasmin inhibitor level. r-SAK alone did not change the bleeding time or coagulation parameters. In conclusion, our findings demonstrate the thrombolytic activity of intravenous bolus injection of the novel thrombolytic agent SAK-RGD-K2-Hirul in rats. Although this protein compares favorably with r-SAK, we were unable to show the presence of any beneficial effects of SAK-RGD-K2-Hirul over those of SAK-RGD-K2-Hir. Furthermore, our results suggest that high doses of SAK-RGD-K2-Hirul bear the risk of bleeding.

  8. Peeter Saks maksab karmavõlga / Paavo Kangur

    Index Scriptorium Estoniae

    Kangur, Paavo, 1966-

    2006-01-01

    Investeerimispanga Suprema Securities juhatuse esimees Peeter Saks oma sportlasekarjäärist, muudatustest investeerimispanga juhtkonnas ning panga tegevusest sportlaste toetamisel. Kommenteerib mäesuusataja Tiiu Nurmberg

  9. Sakīna: contribución a su estudio

    Directory of Open Access Journals (Sweden)

    Tornero, Emilio

    2013-06-01

    Full Text Available This article explores the postkoranic evolution of the term sakīna. First, it examines what previous research has said about that. It then presents, translates, and analizes five texts—which had not been taken into consideration previously— pertaining to the Islamic and philosophical fields in which this term occurs. The texts have been taken from Ibn Ḥabīb, al-Tawḥīdī, the Arabic translation of the Golden Verses, and the two Commentaries on the Golden Verses attributed respectively to Iamblichus and Proclus. The article shows how the Koranic sakīna has evolved in these texts: it connotes pacification of violent animals in Ibn Habib, in al-Tawhidi it denotes a state close to Divinity of characters similar to Sufis: in the Golden Verses, the term sakīna is used to translate daímōn, thanks to which evils originating from innate discord among humans are eliminated; finally, the Commentaries on the Golden Verses contain explanations of this term that are both religious and rationalist.Estudio del término sakīna en su evolución postcoránica en el que se muestra, en primer lugar, lo que la investigación ha dicho sobre él, para, a continuación, presentar, traducir y analizar cinco textos pertenecientes al ámbito islámico y al filosófico en donde aparece dicho término y que no habían sido tenidos en cuenta hasta ahora. Estos textos proceden de: Ibn Ḥabīb, al-Tawḥīdī, traducción árabe de los Versos áureos, y Comentarios de Jámblico y de Proclo a estos Versos áureos. La sakīna coránica evoluciona en estos autores pasando a connotar una pacificación en los animales violentos en Ibn Habib y un estado cercano a la divinidad de caracteres próximos al de los sufíes en al-Tawhidi, mientras que en los Versos áureos se emplea sakīna para traducir daímōn, con sus efectos de eliminación de los males originados por la discordia innata a los hombres. En los Comentarios a los Versos áureos se dan explicaciones, de

  10. Dose-effective investigation of intraarterial r-Sak in canine model with acute cerebral infarctions

    International Nuclear Information System (INIS)

    Liu Sheng; Shi Haibin; Zhang Peng; Wang Chenghu; Zhou Chunguo; Li Linsun

    2007-01-01

    Objective: To compare the effect and complications of intraarterial thrombolysis with different doses of recombinant-staphylokinase (r-Sak) in canine model with acute cerebral infarction, and then to find out the most properly appropriate effective dose. Methods: The model with left cerebral embolism was established with interventional technique in 24 beagle adult dogs. They were randomly divided into 4 groups including control group(saline, 10 ml), group of low dose(r-Sak, 5 000 u/kg), middle dose(r-Sak, 10 000 u/kg) and high dose(r-Sak, 20 000 u/kg). Angiography and intraarterial thrombolysis were performed within 30 minutes after the embolization. Microcatheter was superselectively inserted into left carotid artery. Five hour's later with a repeated angiography at half, 1 and 2 hours after thrombolysis to observe the recanalization. Blood samples were collected at a series of time pre-and post-thrombolysis to test the plasma levels of PT, APTT and D-dimer. These canines were sacrificed, and their cerebri were taken out for pathologic study by the end of 24 hours. Results: The rates of efficacy within 2 hours after thrombolysis were 10.0% (1/10) in control group, 40.0% (4/10) in low dose group, 90.9% (10/11) in middle dose group and 100% (9/9) in high dose group. The rates of complete recanalization were 0, 10% (1/10), 36.4% (4/11) and 66.7% (6/9), correspondingly and respectively. There were statistically obvious differences between the 3 groups (P 0.05). Death occurred in 1 canine(high dose group) within 24 hours after thrombolysis with hemorrhagic lesion in parietal lobe of brain. No other severe complications ocurred. Conclusions: (1) Intraarterial thrombolysis with r-Sak within 5 hours after onset of thrombosis is effective and feasible. Intraarterial r-Sak shows strong thrombolytic effect for white thrombus including a few platelets. There is relative high rate of recanalization with no less than 10 000U/kg of r-Sak but accompanied with high risk of

  11. Sandia reactor kinetics codes: SAK and PK1D

    International Nuclear Information System (INIS)

    Pickard, P.S.; Odom, J.P.

    1978-01-01

    The Sandia Kinetics code (SAK) is a one-dimensional coupled thermal-neutronics transient analysis code for use in simulation of reactor transients. The time-dependent cross section routines allow arbitrary time-dependent changes in material properties. The one-dimensional heat transfer routines are for cylindrical geometry and allow arbitrary mesh structure, temperature-dependent thermal properties, radiation treatment, and coolant flow and heat-transfer properties at the surface of a fuel element. The Point Kinetics 1 Dimensional Heat Transfer Code (PK1D) solves the point kinetics equations and has essentially the same heat-transfer treatment as SAK. PK1D can address extended reactor transients with minimal computer execution time

  12. The KAI Cognitive Style Inventory: Was it personality all along?

    OpenAIRE

    Von Wittich, D.; Antonakis, J.

    2011-01-01

    Kirton's Adaption-Innovation Inventory (KAI) is a widely-used measure of "cognitive style." Surprisingly, there is very little research investigating the discriminant and incremental validity of the KAI. In two studies (n = 213), we examined whether (a) we could predict KAI scores with the "big five" personality dimensions and (b) the KAI scores predicted leadership behavior when controlling for personality and ability. Correcting for measurement error, we found that KAI scores were predicted...

  13. Dephosphorylation of the Core Clock Protein KaiC in the Cyanobacterial KaiABC Circadian Oscillator Proceeds via an ATP Synthase Mechanism

    Energy Technology Data Exchange (ETDEWEB)

    Egli, Martin; Mori, Tetsuya; Pattanayek, Rekha; Xu, Yao; Qin, Ximing; Johnson, Carl H. (Vanderbilt)

    2014-10-02

    The circadian clock of the cyanobacterium Synechococcus elongatus can be reconstituted in vitro from three proteins, KaiA, KaiB, and KaiC in the presence of ATP, to tick in a temperature-compensated manner. KaiC, the central cog of this oscillator, forms a homohexamer with 12 ATP molecules bound between its N- and C-terminal domains and exhibits unusual properties. Both the N-terminal (CI) and C-terminal (CII) domains harbor ATPase activity, and the subunit interfaces between CII domains are the sites of autokinase and autophosphatase activities. Hydrolysis of ATP correlates with phosphorylation at threonine and serine sites across subunits in an orchestrated manner, such that first T432 and then S431 are phosphorylated, followed by dephosphorylation of these residues in the same order. Although structural work has provided insight into the mechanisms of ATPase and kinase, the location and mechanism of the phosphatase have remained enigmatic. From the available experimental data based on a range of approaches, including KaiC crystal structures and small-angle X-ray scattering models, metal ion dependence, site-directed mutagenesis (i.e., E318, the general base), and measurements of the associated clock periods, phosphorylation patterns, and dephosphorylation courses as well as a lack of sequence motifs in KaiC that are typically associated with known phosphatases, we hypothesized that KaiCII makes use of the same active site for phosphorylation and dephosphorlyation. We observed that wild-type KaiC (wt-KaiC) exhibits an ATP synthase activity that is significantly reduced in the T432A/S431A mutant. We interpret the first observation as evidence that KaiCII is a phosphotransferase instead of a phosphatase and the second that the enzyme is capable of generating ATP, both from ADP and P{sub i} (in a reversal of the ATPase reaction) and from ADP and P-T432/P-S431 (dephosphorylation). This new concept regarding the mechanism of dephosphorylation is also supported by the

  14. Aplikasi Penyusunan Laporan Keuangan Berbasis SAK Etap Pada Bagus Agriseta Mandiri

    Directory of Open Access Journals (Sweden)

    Mega Indah Puspita Sari

    2016-03-01

    Full Text Available The purpose of this study is to analyze the arrangement of existing financial report in Bagus Agriseta Mandiri and to conduct the implementation of financial report arrangement that is suitable with SAK ETAP in UKM Bagus Agriseta Mandiri. In this study, the researcher uses case study or field study research that is aimed to learn intensively on the background of problems, situation and the position of the event occurs in nowadays, to solve the problems occurs in company, also the environmental interaction of current social unit in its way (given. The result of this study shows that company only makes loss and profit report, but in its presentation, it still not appropriate with SAK ETAP and financial balance report, cash flow and company equity is not presented yet because of the company less comprehending the standard of arranging financial report. By the existence of SAK ETAP it is expected to create the uniformity in implementing accounting treatment and the presentation of financial report so that it can result appropriate information toward the need of users.

  15. ADP Regulates the Structure and Function of the Protein KaiC

    Science.gov (United States)

    2016-08-11

    LiWang lab exploited this in vitro clock system to gain an atomic -resolution understanding of a circadian clock. The rationale is that fundamental...researchers are Hispanic. On a peer-reviewed research article from the LiWang lab, a Hispanic undergraduate student was an author, as were two non...Using both NMR and fluorescence spectroscopy , the LiWang lab showed that KaiA enhances KaiB-KaiC binding, and KaiC enhances KaiA-KaiB binding (Tseng et

  16. A Myb transcription factor of Phytophthora sojae, regulated by MAP kinase PsSAK1, is required for zoospore development.

    Directory of Open Access Journals (Sweden)

    Meng Zhang

    Full Text Available PsSAK1, a mitogen-activated protein (MAP kinase from Phytophthora sojae, plays an important role in host infection and zoospore viability. However, the downstream mechanism of PsSAK1 remains unclear. In this study, the 3'-tag digital gene expression (DGE profiling method was applied to sequence the global transcriptional sequence of PsSAK1-silenced mutants during the cysts stage and 1.5 h after inoculation onto susceptible soybean leaf tissues. Compared with the gene expression levels of the recipient P. sojae strain, several candidates of Myb family were differentially expressed (up or down in response to the loss of PsSAK1, including of a R2R3-type Myb transcription factor, PsMYB1. qRT-PCR indicated that the transcriptional level of PsMYB1 decreased due to PsSAK1 silencing. The transcriptional level of PsMYB1 increased during sporulating hyphae, in germinated cysts, and early infection. Silencing of PsMYB1 results in three phenotypes: a no cleavage of the cytoplasm into uninucleate zoospores or release of normal zoospores, b direct germination of sporangia, and c afunction in zoospore-mediated plant infection. Our data indicate that the PsMYB1 transcription factor functions downstream of MAP kinase PsSAK1 and is required for zoospore development of P. sojae.

  17. PENGARUH PEMBELAJARAN AKUNTANSI BERBASIS SAK IFRS DAN SELF-EFFICACY TERHADAP KESIAPAN MAHASISWA MENJADI GURU AKUNTANSI

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    Raeni Raeni

    2013-06-01

    Full Text Available The research was inspired by students’ readiness to be Accounting teachers with the rapid progress of science and technology and also free-market for workers. The objective of the study was to test the influence of Accounting learning based on SAK IFRS and self-efficacy toward students’ readiness to be Accounting teachers. The population of the research were Accounting education students in classess of 2010 until 2012. Thus, it used proportionate stratified random sampling. The respondents were 85 students in class 2010, 123 students in class 2011 and 154 students in class 2012. Then, the data were analyzed by percentage descriptive and doubled linear regression. The result of regression analysis showed that 1 Accounting learning based on SAK IFRS and self-efficacy contibuted positively and significantly for 52.4% toward students’ readiness to be Accounting students, 2 there was a positive and significant influence of Accounting learning based on SAK IFRS for 26.2% toward students’ readiness to be Accounting teachers, 3 there was a positive and significant influence of self-efficacy for 16.32% toward students’ readiness to be Accounting teachers. The familiarity level for learning Accounting based on SAK IFRS was high with the progress of science and technology and also full adoption from IFRS.

  18. PENGARUH PEMBELAJARAN AKUNTANSI BERBASIS SAK IFRS DAN SELF-EFFICACY TERHADAP KESIAPAN MAHASISWA MENJADI GURU AKUNTANSI

    Directory of Open Access Journals (Sweden)

    Raeni Raeni

    2016-01-01

    Full Text Available The research was inspired by students’ readiness to be Accounting teachers with the rapid progress of science and technology and also free-market for workers. The objective of the study was to test the influence of Accounting learning based on SAK IFRS and self-efficacy toward students’ readiness to be Accounting teachers. The population of the research were Accounting education students in classess of 2010 until 2012. Thus, it used proportionate stratified random sampling. The respondents were 85 students in class 2010, 123 students in class 2011 and 154 students in class 2012. Then, the data were analyzed by percentage descriptive and doubled linear regression. The result of regression analysis showed that 1 Accounting learning based on SAK IFRS and self-efficacy contibuted positively and significantly for 52.4% toward students’ readiness to be Accounting students, 2 there was a positive and significant influence of Accounting learning based on SAK IFRS for 26.2% toward students’ readiness to be Accounting teachers, 3 there was a positive and significant influence of self-efficacy for 16.32% toward students’ readiness to be Accounting teachers. The familiarity level for learning Accounting based on SAK IFRS was high with the progress of science and technology and also full adoption from IFRS.

  19. Circadian clock protein KaiC forms ATP-dependent hexameric rings and binds DNA.

    Science.gov (United States)

    Mori, Tetsuya; Saveliev, Sergei V; Xu, Yao; Stafford, Walter F; Cox, Michael M; Inman, Ross B; Johnson, Carl H

    2002-12-24

    KaiC from Synechococcus elongatus PCC 7942 (KaiC) is an essential circadian clock protein in cyanobacteria. Previous sequence analyses suggested its inclusion in the RecADnaB superfamily. A characteristic of the proteins of this superfamily is that they form homohexameric complexes that bind DNA. We show here that KaiC also forms ring complexes with a central pore that can be visualized by electron microscopy. A combination of analytical ultracentrifugation and chromatographic analyses demonstrates that these complexes are hexameric. The association of KaiC molecules into hexamers depends on the presence of ATP. The KaiC sequence does not include the obvious DNA-binding motifs found in RecA or DnaB. Nevertheless, KaiC binds forked DNA substrates. These data support the inclusion of KaiC into the RecADnaB superfamily and have important implications for enzymatic activity of KaiC in the circadian clock mechanism that regulates global changes in gene expression patterns.

  20. Sakārtojuma nevienādības

    OpenAIRE

    Popmane, Daiga

    2008-01-01

    Darbā tiek apskatīta viena no nevienādību teorijas sastāvdaļām – sakārtojuma nevienādības, kā arī daži to lietojumi. Darbā ir aplūkoti arī vairāki uzdevumi no dažādu gadu matemātikas olimpiādēm.

  1. The Legionella pneumophila kai operon is implicated in stress response and confers fitness in competitive environments

    Science.gov (United States)

    Loza-Correa, Maria; Sahr, Tobias; Rolando, Monica; Daniels, Craig; Petit, Pierre; Skarina, Tania; Valero, Laura Gomez; Dervins-Ravault, Delphine; Honoré, Nadine; Savchenko, Aleksey; Buchrieser, Carmen

    2014-01-01

    Summary Legionella pneumophila uses aquatic protozoa as replication niche and protection from harsh environments. Although L. pneumophila is not known to have a circadian clock, it encodes homologues of the KaiBC proteins of Cyanobacteria that regulate circadian gene expression. We show that L. pneumophila kaiB, kaiC and the downstream gene lpp1114, are transcribed as a unit under the control of the stress sigma factor RpoS. KaiC and KaiB of L. pneumophila do not interact as evidenced by yeast and bacterial two-hybrid analyses. Fusion of the C-terminal residues of cyanobacterial KaiB to Legionella KaiB restores their interaction. In contrast, KaiC of L. pneumophila conserved autophosphorylation activity, but KaiB does not trigger the dephosphorylation of KaiC like in Cyanobacteria. The crystal structure of L. pneumophila KaiB suggests that it is an oxidoreductase-like protein with a typical thioredoxin fold. Indeed, mutant analyses revealed that the kai operon-encoded proteins increase fitness of L. pneumophila in competitive environments, and confer higher resistance to oxidative and sodium stress. The phylogenetic analysis indicates that L. pneumophila KaiBC resemble Synechosystis KaiC2B2 and not circadian KaiB1C1. Thus, the L. pneumophila Kai proteins do not encode a circadian clock, but enhance stress resistance and adaption to changes in the environments. PMID:23957615

  2. Kai Kaljo: "Aeg-ajalt tuleb ennast peeglist vaadata" / Kai Kaljo ; intervjueerinud Reet Varblane

    Index Scriptorium Estoniae

    Kaljo, Kai, 1959-

    2009-01-01

    Videokunstnik Kai Kaljo oma isikunäitusest "Ainult eestlastele" Tallinna Kunstihoone galeriis, maalikunstisti tähendusest talle, kunstiteostest, mis on teda mõjutanud, Tallinnasse püstitatud Vabadussõja võidusambast

  3. Forgotten evidence: A mixed methods study of why sexual assault kits (SAKs) are not submitted for DNA forensic testing.

    Science.gov (United States)

    Campbell, Rebecca; Fehler-Cabral, Giannina; Bybee, Deborah; Shaw, Jessica

    2017-10-01

    Throughout the United States, hundreds of thousands of sexual assault kits (SAKs) (also termed "rape kits") have not been submitted by the police for forensic DNA testing. DNA evidence can help sexual assault investigations and prosecutions by identifying offenders, revealing serial offenders through DNA matches across cases, and exonerating those who have been wrongly accused. In this article, we describe a 5-year action research project conducted with 1 city that had large numbers of untested SAKs-Detroit, Michigan-and our examination into why thousands of rape kits in this city were never submitted for forensic DNA testing. This mixed methods study combined ethnographic observations and qualitative interviews to identify stakeholders' perspectives as to why rape kits were not routinely submitted for testing. Then, we quantitatively examined whether these factors may have affected police practices regarding SAK testing, as evidenced by predictable changes in SAK submission rates over time. Chronic resource scarcity only partially explained why the organizations that serve rape victims-the police, crime lab, prosecution, and victim advocacy-could not test all rape kits, investigate all reported sexual assaults, and support all rape survivors. SAK submission rates significantly increased once criminal justice professionals in this city had full access to the FBI DNA forensic database Combined DNA Index System (CODIS), but even then, most SAKs were still not submitted for DNA testing. Building crime laboratories' capacities for DNA testing and training police on the utility of forensic evidence and best practices in sexual assault investigations can help remedy, and possibly prevent, the problem of untested rape kits. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  4. Role of the Talaromyces marneffei (Penicillium marneffei) sakA gene in nitrosative stress response, conidiation and red pigment production.

    Science.gov (United States)

    Nimmanee, Panjaphorn; Tam, Emily W T; Woo, Patrick C Y; Vanittanakom, Pramote; Vanittanakom, Nongnuch

    2017-04-01

    Stress-activated MAPK pathways are systems used to regulate the stress adaptation of most fungi. It has been shown that in Talaromyces marneffei (Penicillium marneffei), a pathogenic dimorphic fungus, the sakA gene is involved, not only in tolerance against oxidative and heat stresses, but also in playing a role in asexual development, yeast cell generation in vitro and survival inside macrophage cell lines. In this study, the role of the T. marneffei sakA gene on the nitrosative stress response and the regulation of gene expression were investigated. The susceptibility of the sakA mutant to NaNO2 was investigated using drop dilution assay and the expression of genes of interest were determined by RT-PCR, comparing them to the wild-type and complemented strains. The results demonstrated that the T. marneffei sakA gene played a role in the stress response to NaNO2, the expression of genes functioning in conidial development (brlA, abaA and wetA) and red pigment biosynthesis (pks3, rp1, rp2 and rp3). These findings suggest that T. marneffei sakA is broadly involved in a wide variety of cell activities, including stress response, cell morphogenesis, asexual development and pigmentation. © FEMS 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  5. Eesti disaini uudised / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2005-01-01

    Toivo Raidmetsa isiknäitus "Barokist dadani" Rotermanni soolalaos, tekstiilikunstnik Helena Palmi ehted. Disainitudeng Liina-Kai Raivet sai teise koha Itaalias keraamiliste plaatide konkursil "Marchitecture"

  6. DA Masolo A Review of Kai Kresse's Philosophising in Mombasa ...

    African Journals Online (AJOL)

    DA Masolo

    Kai Kresse's Philosophising in Mombasa: Knowledge, Islam and Intellectual Practice on the Swahili Coast 1. A Review of Kai ... (Edinburgh: Edinburgh University Press, 2007, for the. International African Institute, London, in collaboration with.

  7. Intervjuu Kai Vöckleriga = Interview with Kai Vöckler / intervjueerinud Triin Ojaste

    Index Scriptorium Estoniae

    Vöckler, Kai

    2011-01-01

    Lääne-Saksamaal sündinud urbanist, urbanistikaga tegeleva organisatsiooni Archis Interventions'i üks asutaja Kai Vöckler endast, Archis Interventions'i tegevusest, Ida-Euroopast, Balkanist, uuest arhitektuurist ja linnaehitusest, uue vabaduse antud võimalustest ja selle mõiste mitmetähenduslikkusest

  8. Acute Treatment with T-Type Calcium Channel Enhancer SAK3 Reduces Cognitive Impairments Caused by Methimazole-Induced Hypothyroidism Via Activation of Cholinergic Signaling.

    Science.gov (United States)

    Husain, Noreen; Yabuki, Yasushi; Shinoda, Yasuharu; Fukunaga, Kohji

    2018-01-01

    Hypothyroidism is a common disorder that is associated with psychological disturbances such as dementia, depression, and psychomotor disorders. We recently found that chronic treatment with the T-type calcium channel enhancer SAK3 prevents the cholinergic neurodegeneration induced by a single intraperitoneal (i.p.) injection of methimazole (MMI; 75 mg/kg), thereby improving cognition. Here, we evaluated the acute effect of SAK3 on cognitive impairments and its mechanism of action following the induction of hypothyroidism. Hypothyroidism was induced by 2 injections of MMI (75 mg/kg, i.p.) administered once per week. Four weeks after the final MMI treatment, MMI-treated mice showed reduced serum thyroxine (T4) levels and cognitive impairments without depression-like behaviors. Although acute SAK3 (1.0 mg/kg, p.o.) administration failed to ameliorate the decreased T4 levels and histochemical destruction of the glomerular structure, acute SAK3 (1.0 mg/kg, p.o.) administration significantly reduced cognitive impairments in MMI-treated mice. Importantly, the α7 nicotinic acetylcholine receptor (nAChR)-selective inhibitor methyllycaconitine (MLA; 12 mg/kg, i.p.) and T-type calcium channel-specific blocker NNC 55-0396 (25 mg/kg, i.p.) antagonized the acute effect of SAK3 on memory deficits in MMI-treated mice. We also confirmed that acute SAK3 administration does not rescue reduced olfactory marker protein or choline acetyltransferase immunoreactivity levels in the olfactory bulb or medial septum. Taken together, these results suggest that SAK3 has the ability to improve the cognitive decline caused by hypothyroidism directly through activation of nAChR signaling and T-type calcium channels. © 2018 S. Karger AG, Basel.

  9. Hea kultuuriantropoloog peab olema empaatiline / Kai Herkel ; intervjueerinud Reet Varblane

    Index Scriptorium Estoniae

    Herkel, Kai, 1963-

    2009-01-01

    Kai Herkeli Tiibeti-teemalisest näitusest "Himaalaja lapsed" Tallinna Linnagaleriis. Eksponeeritud fotod ja videod. Kai Herkel teeb Helsingi ülikooli sotsiaal- ja kultuuriantropoloogia erialal magistritööd lapsmunkade elust, oma kunstiprojektis on ta keskendunud Lamayuru kloostrikoolis õppivatele lapsmunkadele

  10. Kai Kaljo video-workshopil Ljubljanas

    Index Scriptorium Estoniae

    2000-01-01

    Video-workshop "Crossing Over 4" 9.-23. XII 1999 Ljubljana meedialaboris. Korraldajad videokunsti professor Nina Czegledy Torontost ja bulgaaria kuraator Iliyana Nedkova. Eestit esindanud Kai Kaljo esitas videos "Pathetique" oma versiooni Beethoveni "Pateetilisest sonaadist"

  11. SOLVENT-BASED ENHANCED OIL RECOVERY PROCESSES TO DEVELOP WEST SAK ALASKA NORTH SLOPE HEAVY OIL RESOURCES

    Energy Technology Data Exchange (ETDEWEB)

    David O. Ogbe; Tao Zhu

    2004-01-01

    A one-year research program is conducted to evaluate the feasibility of applying solvent-based enhanced oil recovery processes to develop West Sak and Ugnu heavy oil resources found on the Alaska North Slope (ANS). The project objective is to conduct research to develop technology to produce and market the 300-3000 cp oil in the West Sak and Ugnu sands. During the first phase of the research, background information was collected, and experimental and numerical studies of vapor extraction process (VAPEX) in West Sak and Ugnu are conducted. The experimental study is designed to foster understanding of the processes governing vapor chamber formation and growth, and to optimize oil recovery. A specially designed core-holder and a computed tomography (CT) scanner was used to measure the in-situ distribution of phases. Numerical simulation study of VAPEX was initiated during the first year. The numerical work completed during this period includes setting up a numerical model and using the analog data to simulate lab experiments of the VAPEX process. The goal was to understand the mechanisms governing the VAPEX process. Additional work is recommended to expand the VAPEX numerical study using actual field data obtained from Alaska North Slope.

  12. Cisplatin Induces Up-Regulation of KAI1, a Metastasis Suppressor ...

    African Journals Online (AJOL)

    Purpose: To investigate the effect of cisplatin on cell toxicity and metastasis through modulation of KAI1 gene expression. Methods: MCF-7cells were incubated with different concentrations of cisplatin for 24 h. RNA was extracted by trizol and cDNA synthesized. KAI1 and TBP were chosen as target and internal control ...

  13. The structure of the karrikin-insensitive protein (KAI2) in Arabidopsis thaliana.

    Science.gov (United States)

    Bythell-Douglas, Rohan; Waters, Mark T; Scaffidi, Adrian; Flematti, Gavin R; Smith, Steven M; Bond, Charles S

    2013-01-01

    KARRIKIN INSENSITIVE 2 (KAI2) is an α/β hydrolase involved in seed germination and seedling development. It is essential for plant responses to karrikins, a class of butenolide compounds derived from burnt plant material that are structurally similar to strigolactone plant hormones. The mechanistic basis for the function of KAI2 in plant development remains unclear. We have determined the crystal structure of Arabidopsis thaliana KAI2 in space groups P2(1) 2(1) 2(1) (a =63.57 Å, b =66.26 Å, c =78.25 Å) and P2(1) (a =50.20 Å, b =56.04 Å, c =52.43 Å, β =116.12°) to 1.55 and 2.11 Å respectively. The catalytic residues are positioned within a large hydrophobic pocket similar to that of DAD2, a protein required for strigolactone response in Petunia hybrida. KAI2 possesses a second solvent-accessible pocket, adjacent to the active site cavity, which offers the possibility of allosteric regulation. The structure of KAI2 is consistent with its designation as a serine hydrolase, as well as previous data implicating the protein in karrikin and strigolactone signalling.

  14. The structure of the karrikin-insensitive protein (KAI2 in Arabidopsis thaliana.

    Directory of Open Access Journals (Sweden)

    Rohan Bythell-Douglas

    Full Text Available KARRIKIN INSENSITIVE 2 (KAI2 is an α/β hydrolase involved in seed germination and seedling development. It is essential for plant responses to karrikins, a class of butenolide compounds derived from burnt plant material that are structurally similar to strigolactone plant hormones. The mechanistic basis for the function of KAI2 in plant development remains unclear. We have determined the crystal structure of Arabidopsis thaliana KAI2 in space groups P2(1 2(1 2(1 (a =63.57 Å, b =66.26 Å, c =78.25 Å and P2(1 (a =50.20 Å, b =56.04 Å, c =52.43 Å, β =116.12° to 1.55 and 2.11 Å respectively. The catalytic residues are positioned within a large hydrophobic pocket similar to that of DAD2, a protein required for strigolactone response in Petunia hybrida. KAI2 possesses a second solvent-accessible pocket, adjacent to the active site cavity, which offers the possibility of allosteric regulation. The structure of KAI2 is consistent with its designation as a serine hydrolase, as well as previous data implicating the protein in karrikin and strigolactone signalling.

  15. Kai Kaljo tunnustatus jätkub

    Index Scriptorium Estoniae

    2000-01-01

    Kai Kaljo esinemisest kuraator Hans Knolli näitusel "Communication...", New Yorgis Branka Stipancici kureeritud näitusel "Chinese whispers", Lõuna-Koreas Tom van Vliet kureeritud VI Pusani rahvusvahelisel kaasaegse kunsti festivalil, "World Wide Video" festivalil Amsterdamis

  16. Expression of KAI1/CD82 and MRP-1/CD9 in transitional cell carcinoma of bladder.

    Science.gov (United States)

    Ai, Xing; Zhang, Xu; Wu, Zhun; Ma, Xin; Ju, Zhenghua; Wang, Baojun; Shi, Taoping

    2007-02-01

    The expression of KAI1/CD82 and MRP-1/CD9 in transitional cell carcinoma of bladder (TCCB) and its clinical significance were investigated. Immunohistochemistry was used to detect KAI1/CD82 and MRP-1/CD9 protein expression in 52 TCCB specimens. Correlation between the expression of KAI1/CD82 and MRP-1/CD9 to clinicopathologic factors was statistically analyzed. The results showed that the positive rate of KAI1/CD82 and MRP-1/CD9 in TCCB was 50% and 61.5%, respectively. The MRP-1/CD9 and KAI1/CD82 expression was significantly associated with grade of TCCB (PMRP-1/CD9 or KAI1/CD82 expression and clinical stage of TCCB (P>0.05). The expression level of MRP-1/CD9 and KAI1/CD82 in recurrent TCCB samples was lower than that in non-recurrent samples (PMRP-1/CD9 expression was statistically significant (r=0.316, PMRP-1/CD9 expression may be important prognostic indicators and potentially useful for assessing the biological behavior of TCCB.

  17. The Aspergillus fumigatus SchASCH9 kinase modulates SakAHOG1 MAP kinase activity and it is essential for virulence.

    Science.gov (United States)

    Alves de Castro, Patrícia; Dos Reis, Thaila Fernanda; Dolan, Stephen K; Oliveira Manfiolli, Adriana; Brown, Neil Andrew; Jones, Gary W; Doyle, Sean; Riaño-Pachón, Diego M; Squina, Fábio Márcio; Caldana, Camila; Singh, Ashutosh; Del Poeta, Maurizio; Hagiwara, Daisuke; Silva-Rocha, Rafael; Goldman, Gustavo H

    2016-11-01

    The serine-threonine kinase TOR, the Target of Rapamycin, is an important regulator of nutrient, energy and stress signaling in eukaryotes. Sch9, a Ser/Thr kinase of AGC family (the cAMP-dependent PKA, cGMP- dependent protein kinase G and phospholipid-dependent protein kinase C family), is a substrate of TOR. Here, we characterized the fungal opportunistic pathogen Aspergillus fumigatus Sch9 homologue (SchA). The schA null mutant was sensitive to rapamycin, high concentrations of calcium, hyperosmotic stress and SchA was involved in iron metabolism. The ΔschA null mutant showed increased phosphorylation of SakA, the A. fumigatus Hog1 homologue. The schA null mutant has increased and decreased trehalose and glycerol accumulation, respectively, suggesting SchA performs different roles for glycerol and trehalose accumulation during osmotic stress. The schA was transcriptionally regulated by osmotic stress and this response was dependent on SakA and MpkC. The double ΔschA ΔsakA and ΔschA ΔmpkC mutants were more sensitive to osmotic stress than the corresponding parental strains. Transcriptomics and proteomics identified direct and indirect targets of SchA post-exposure to hyperosmotic stress. Finally, ΔschA was avirulent in a low dose murine infection model. Our results suggest there is a complex network of interactions amongst the A. fumigatus TOR, SakA and SchA pathways. © 2016 John Wiley & Sons Ltd.

  18. Kais-Vesik said ebameeldiva vastase / Andres Kalvik

    Index Scriptorium Estoniae

    Kalvik, Andres, 1982-

    2007-01-01

    Stavangeris Suure Slämmi alagrupis kolmanda koha saanud ning koha 24 parema seas taganud Kristjan Kais ja Rivo Vesik lähevad play-off'i avaringis vastamisi Saksamaa duoga Mischa Urbatzka - Jonas Reckermann

  19. KAI1 suppresses HIF-1α and VEGF expression by blocking CDCP1-enhanced Src activation in prostate cancer

    Directory of Open Access Journals (Sweden)

    Park Jung-Jin

    2012-03-01

    Full Text Available Abstract Background KAI1 was initially identified as a metastasis-suppressor gene in prostate cancer. It is a member of the tetraspan transmembrane superfamily (TM4SF of membrane glycoproteins. As part of a tetraspanin-enriched microdomain (TEM, KAI1 inhibits tumor metastasis by negative regulation of Src. However, the underlying regulatory mechanism has not yet been fully elucidated. CUB-domain-containing protein 1 (CDCP1, which was previously known as tetraspanin-interacting protein in TEM, promoted metastasis via enhancement of Src activity. To better understand how KAI1 is involved in the negative regulation of Src, we here examined the function of KAI1 in CDCP1-mediated Src kinase activation and the consequences of this process, focusing on HIF-1 α and VEGF expression. Methods We used the human prostate cancer cell line PC3 which was devoid of KAI1 expression. Vector-transfected cells (PC3-GFP clone #8 and KAI1-expressing PC3 clones (PC3-KAI1 clone #5 and #6 were picked after stable transfection with KAI1 cDNA and selection in 800 μg/ml G418. Protein levels were assessed by immunoblotting and VEGF reporter gene activity was measured by assaying luciferase activitiy. We followed tumor growth in vivo and immunohistochemistry was performed for detection of HIF-1, CDCP1, and VHL protein level. Results We demonstrated that Hypoxia-inducible factor 1α (HIF-1α and VEGF expression were significantly inhibited by restoration of KAI1 in PC3 cells. In response to KAI1 expression, CDCP1-enhanced Src activation was down-regulated and the level of von Hippel-Lindau (VHL protein was significantly increased. In an in vivo xenograft model, KAI1 inhibited the expression of CDCP1 and HIF-1α. Conclusions These novel observations may indicate that KAI1 exerts profound metastasis-suppressor activity in the tumor malignancy process via inhibition of CDCP1-mediated Src activation, followed by VHL-induced HIF-1α degradation and, ultimately, decreased VEGF

  20. Pühendumusuuringute tegemine pole levinud / Kai Vare

    Index Scriptorium Estoniae

    Vare, Kai, 1968-

    2004-01-01

    Reval Hotelligrupp AS-is ja Saku Õlletehases läbi viidud töötajate rahulolu-uuringutest. Kommenteerivad Mari-Liis Eensalu, Kai Prinits ja Tiiu Vilms. Vt. samas: Narva Elektrivõrkudes töötavad Euroopa pühendunuimad inimesed

  1. Tumor suppressor KAI1 affects integrin αvβ3-mediated ovarian cancer cell adhesion, motility, and proliferation

    International Nuclear Information System (INIS)

    Ruseva, Zlatna; Geiger, Pamina Xenia Charlotte; Hutzler, Peter; Kotzsch, Matthias; Luber, Birgit; Schmitt, Manfred; Gross, Eva; Reuning, Ute

    2009-01-01

    The tetraspanin KAI1 had been described as a metastasis suppressor in many different cancer types, a function for which associations of KAI1 with adhesion and signaling receptors of the integrin superfamily likely play a role. In ovarian cancer, integrin αvβ3 correlates with tumor progression and its elevation in vitro provoked enhanced cell adhesion accompanied by significant increases in cell motility and proliferation in the presence of its major ligand vitronectin. In the present study, we characterized integrin αvβ3-mediated tumor biological effects as a function of cellular KAI1 restoration and proved for the first time that KAI1, besides its already known physical crosstalk with β1-integrins, also colocalizes with integrin αvβ3. Functionally, elevated KAI1 levels drastically increased integrin αvβ3/vitronectin-dependent ovarian cancer cell adhesion. Since an intermediate level of cell adhesive strength is required for optimal cell migration, we next studied ovarian cancer cell motility as a function of KAI1 restoration. By time lapse video microscopy, we found impaired integrin αvβ3/vitronectin-mediated cell migration most probably due to strongly enhanced cellular immobilization onto the adhesion-supporting matrix. Moreover, KAI1 reexpression significantly diminished cell proliferation. These data strongly indicate that KAI1 may suppress ovarian cancer progression by inhibiting integrin αvβ3/vitronectin-provoked tumor cell motility and proliferation as important hallmarks of the oncogenic process.

  2. Overexpression of KAI1 induces autophagy and increases MiaPaCa-2 cell survival through the phosphorylation of extracellular signal-regulated kinases

    International Nuclear Information System (INIS)

    Wu, Chun-Yan; Yan, Jun; Yang, Yue-Feng; Xiao, Feng-Jun; Li, Qing-Fang; Zhang, Qun-Wei; Wang, Li-Sheng; Guo, Xiao-Zhong; Wang, Hua

    2011-01-01

    Research highlights: → We first investigate the effects of KAI1 on autophagy in MiaPaCa-2 cells. → Our findings demonstrate that KAI1 induces autophagy, which in turn inhibits KAI1-induced apoptosis. → This study also supplies a possible novel therapeutic method for the treatment of pancreatic cancer using autophagy inhibitors. -- Abstract: KAI1, a metastasis-suppressor gene belonging to the tetraspanin family, is known to inhibit cancer metastasis without affecting the primary tumorigenicity by inhibiting the epidermal growth factor (EGF) signaling pathway. Recent studies have shown that hypoxic conditions of solid tumors induce high-level autophagy and KAI1 expression. However, the relationship between autophagy and KAI1 remains unclear. By using transmission electron microscopy, confocal microscopy, and Western blotting, we found that KAI1 can induce autophagy in a dose- and time-dependent manner in the human pancreatic cell line MiaPaCa-2. KAI1-induced autophagy was confirmed by the expression of autophagy-related proteins LC3 and Beclin 1. KAI1 induces autophagy through phosphorylation of extracellular signal-related kinases rather than that of AKT. KAI1-induced autophagy protects MiaPaCa-2 cells from apoptosis and proliferation inhibition partially through the downregulation of poly [adenosine diphosphate (ADP)-ribose] polymerase (PARP) cleavage and caspase-3 activation.

  3. [Liivimaa valgustaja August Wilhelm Hupel 1737- 1819] / Kai Reemann

    Index Scriptorium Estoniae

    Reemann, Kai

    2010-01-01

    Eesti Looduseuurijate Selts raamatukogu juhataja Kai Reemann tutvustab nii raamatukogu kui ka 2004. aastal parimaks ajalooraamatuks tunnistatud teost "Liivimaa valgustaja August Wilhelm Hupel 1737- 1819" (Tallinn, 2004)

  4. O tempora, o mores! / Maria-Kristiina Lotman, Kai Tafenau

    Index Scriptorium Estoniae

    Lotman, Maria-Kristiina, 1974-

    2011-01-01

    Tutvustus: Sallustius. Catilina vandenõu / Gaius Sallustius Crispus ; ladina keelest tõlkinud Maria-Kristiina Lotman ja Kai Tafenau. Tallinn : Tallinna Ülikooli Kirjastus, 2011. (Bibliotheca antiqua (Tallinna Ülikool))

  5. Neuroprotective mechanism of Kai Xin San: upregulation of hippocampal insulin-degrading enzyme protein expression and acceleration of amyloid-beta degradation

    Directory of Open Access Journals (Sweden)

    Na Wang

    2017-01-01

    Full Text Available Kai Xin San is a Chinese herbal formula composed of Radix Ginseng , Poria , Radix Polygalae and Acorus Tatarinowii Rhizome . It has been used in China for many years for treating amnesia. Kai Xin San ameliorates amyloid-β (Aβ-induced cognitive dysfunction and is neuroprotective in vivo , but its precise mechanism remains unclear. Expression of insulin-degrading enzyme (IDE, which degrades Aβ, is strongly correlated with cognitive function. Here, we injected rats with exogenous Aβ42 (200 μM, 5 μL into the hippocampus and subsequently administered Kai Xin San (0.54 or 1.08 g/kg/d intragastrically for 21 consecutive days. Hematoxylin-eosin and Nissl staining revealed that Kai Xin San protected neurons against Aβ-induced damage. Furthermore, enzyme-linked immunosorbent assay, western blot and polymerase chain reaction results showed that Kai Xin San decreased Aβ42 protein levels and increased expression of IDE protein, but not mRNA, in the hippocampus. Our findings reveal that Kai Xin San facilitates hippocampal Aβ degradation and increases IDE expression, which leads, at least in part, to the alleviation of hippocampal neuron injury in rats.

  6. Use of pipe saks on pipeline construction

    Energy Technology Data Exchange (ETDEWEB)

    Ghio, Alberto F.M.; Caciatori, Angelo [Galvao Engenharia S.A., Sao Paulo, SP (Brazil); Ruschi, Allan A.; Santos, Felipe A. dos; Barros, Horacio B. de; Loureiro, Regis R. [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil)

    2009-07-01

    The use of new technologies applied to pipeline construction and assembling, aimed at enhancing productivity has been searched by PETROBRAS, throughout its subcontractors, assemblers, by transference in the mentioned constructions. Along the construction of Cacimbas Catu Pipeline, Spread 1 A, placed between the Cacimbas Gas Treatment Station (Linhares, ES) and the future Compression Station of Sao Mateus (ES), one, by means of surveys, noticed that the length of flooded or prone to flooding areas was way superior to the ones foreseen in the basic design. One of the broadly used methods for assuring buoyancy control is concreting the pipes. Such method deeply impacts work's logistics in for instance, the pipe stringing work; in this one, a maximum load of two pipes can be transported until the area to applied, what leads to lower productivity and higher risk due to the increase of trips by heavy load trucks. As an alternative to regular concrete, the Pipe Sak System was adopted and such method improved productivity and decreased discontinuities. (author)

  7. Muusikud on koolitatud palgamõrvareiks / Kai Kallastu ; interv. Karol Kallas

    Index Scriptorium Estoniae

    Kallastu, Kai, 1970-

    2007-01-01

    Lauljanna oma eelseisvast esietendusest : Pärnu mudaravilas esietendub täna Sven Kivisildniku audiovisuaalne ooperietendus "Topeltwagner juustuga", teostajaks lavastuse meeskond REPOO ENSEMBLE (Kivisildnik, Andrus ja Kai Kallastu, Indrek ja Leonora Palu, Rein Laos)

  8. Hotelli Radisson SAS mantra : jah, ma saan! / Kai Vare

    Index Scriptorium Estoniae

    Vare, Kai, 1968-

    2004-01-01

    Radisson SAS hotell Tallinnas on kliendirahulolu-uuringute järgi keti hotellide seas esimeste hulgas. Hotelli direktor Kaido Ojaperv ja müügijuht Ann-Kai Tõrs Radisson SAS-i standarditest, kliendi sajaprotsendilise rahulolu tagamise põhimõtetest, personali valikust, koolitusest. Kommenteerib Sandra Dimitrovich

  9. Videoinstallatsiooni aeg pole ümber : muljeid Amsterdami videofestivalilt / Kai Kaljo

    Index Scriptorium Estoniae

    Kaljo, Kai, 1959-

    1999-01-01

    17. World Wide Video Festival 15.-20. IX Amsterdamis Melkwegi keskuses ja Stedelijki muuseumis. Väljapanekust. Kai Kaljolt oli videofestivalil väljas 'One Way to See America'. Seminaride materjalid: wwvf@wwvf.demon ja www.wwvf.nl

  10. Cisplatin Induces Up-Regulation of KAI1, a Metastasis Suppressor ...

    African Journals Online (AJOL)

    HP

    including breast, testicular, ovarian, cervical, prostate, head and neck, ..... Vertebral bone metastasis in breast cancer: a case report. Rom J Morphol Embryol 2011; 52: 897-. 905. ... KAI1/CD82 on the β1 integrin maturation in highly migratory ...

  11. The HANS KAI Project: a community-based approach to improving health and well-being through peer support

    Directory of Open Access Journals (Sweden)

    Alexandra Henteleff

    2018-03-01

    Full Text Available Introduction: HANS KAI is a unique health promotion intervention to improve participants’ health by focussing on interrelated chronic disease prevention behaviours through peer support and strengthening of social support networks. The study objective was to determine the effectiveness of HANS KAI in an urban Canadian setting. Methods: We used a mixed methods intervention research design that involved multiple sites from November 2010 to April 2015. Data was obtained from participant surveys as well as in-person interviews at zero, 6, 12 and 24 months. Participants met in groups at least once a month during the research period, to self-monitor health indicators, prepare and share a healthy snack, participate in a physical activity, set a healthy lifestyle goal (optional and socialize. Results: There were statistically significant mental health improvements from pre- to post-program, and 66% of the participants described specific behaviour changes as a result of HANS KAI participation. Additional positive health impacts included peer support; acquiring specific health knowledge; inspiration, motivation or accountability; the empowering effect of monitoring one’s own health indicators; overcoming social isolation and knowing how to better access services. Conclusion: The need to identify innovative ways to address chronic disease prevention and management has been the driver for implementing and evaluating HANS KAI. While further research will be required to validate the present findings, it appears that HANS KAI may be an effective approach to create environments that empower community members to support each other while promoting healthy lifestyle choices and detecting early changes in health status.

  12. Kai Kaljo : Autsaiderist staar = Star Outsider / Mari Laaniste

    Index Scriptorium Estoniae

    Laaniste, Mari, 1977-

    2007-01-01

    Vitraaži õppinud Kai Kaljost kui tänapäevasest installatsioonikunstnikust, kelle loomingut iseloomustab irooniline lähenemine eksistentsiaalsetele teemadele ja kes kodumaal on pikka aega "mittesoovitud" olnud. Maailmavaatlemise ja hetketabamise kõrval on tal hinge peal ka kunsti positsioon ühiskonnas ja ühiskonna suhtumine kunstnikku, ta on varmas osutama ümbritseva maailma vildakatele väärtushinnangutele ja eetilisele ambivalentsusele

  13. Modeled Oceanic Response and Sea Surface Cooling to Typhoon Kai-Tak

    Directory of Open Access Journals (Sweden)

    Yu-Heng Tseng

    2010-01-01

    Full Text Available An ocean response to typhoon Kai-Tak is simulated using an accurate fourth-order, basin-scale ocean model. The surface winds of typhoon Kai-Tak were obtained from QuikSCAT satellite images blended with the ECMWF wind fields. An intense nonlinear mesoscale eddy is generated in the northeast South China Sea (SCS with a Rossby number of O(1 and on a 50 - 100 km horizontal scale. Inertial oscillation is clearly observed. Advection dominates as a strong wind shear drives the mixed layer flows outward, away from the typhoon center, thus forcing upwelling from deep levels with a high upwelling velocity (> 30 m day-1. A drop in sea surface temperature (SST of more than 9°C is found in both observation and simulation. We attribute this significant SST drop to the influence of the slow moving typhoon, initial stratification and bathymetry-induced upwelling in the northeast of the SCS where the typhoon hovered.

  14. Karrikin-KAI2 signalling provides Arabidopsis seeds with tolerance to abiotic stress and inhibits germination under conditions unfavourable to seedling establishment.

    Science.gov (United States)

    Wang, Lu; Waters, Mark T; Smith, Steven M

    2018-05-04

    The control of seed germination in response to environmental conditions is important for plant success. We investigated the role of the karrikin receptor KARRIKIN INSENSITIVE2 (KAI2) in the response of Arabidopsis seeds to osmotic stress, salinity and high temperature. Germination of the kai2 mutant was examined in response to NaCl, mannitol and elevated temperature. The effect of karrikin on germination of wild-type seeds, hypocotyl elongation and the expression of karrikin-responsive genes was also examined in response to such stresses. The kai2 seeds germinated less readily than wild-type seeds and germination was more sensitive to inhibition by abiotic stress. Karrikin-induced KAI2 signalling stimulated germination of wild-type seeds under favourable conditions, but, surprisingly, inhibited germination in the presence of osmolytes or at elevated temperature. By contrast, GA stimulated germination of wild-type seeds and mutants under all conditions. Karrikin induced expression of DLK2 and KUF1 genes and inhibited hypocotyl elongation independently of osmotic stress. Under mild osmotic stress, karrikin enhanced expression of DREB2A, WRKY33 and ERF5 genes, but not ABA signalling genes. Thus, the karrikin-KAI2 signalling system can protect against abiotic stress, first by providing stress tolerance, and second by inhibiting germination under conditions unfavourable to seedling establishment. © 2018 The Authors. New Phytologist © 2018 New Phytologist Trust.

  15. Georgi söögituba Väike-Maarjas / Kai Tort, Ilmar Aasumets

    Index Scriptorium Estoniae

    Tort, Kai

    2006-01-01

    7 ill.; Georg Lurichi järgi nime saanud söögituba asub arhitekt Alar Kotli vanaisale kuulunud hoones; söögitoa kujunduse tegi Kai Tort, mööbli valmistasid kohalikud puusepad, plekist lambid - Ilmar Aasumets, omanik Avo Part

  16. Kai Adolf Jensen, professor i almindelig patologi

    DEFF Research Database (Denmark)

    Høiby, Niels

    2016-01-01

    for the Bacillus Calmette-Guérin vaccine production and supervised many young scientists’ doctoral theses on the aspects of tuberculosis. He became internationally recognized, and he revealed an important scientific fraud in the laboratory of the Austrian professor Ernst Löwenstein (1878-1950), who claimed that he...... could detect M. tuberculosis in blood cultures as a cause of a multitude of diseases. He was a pioneer in eradication of bovine tuberculosis in Denmark which became the first country in the world where this happened. Kai Adolf Jensen held the position as professor of general pathology from 1940 to 1965...

  17. Ähvardus : olümpiamängude teleülekanne jääb ära / Kai Kalamees

    Index Scriptorium Estoniae

    Kalamees, Kai

    2005-01-01

    Riigikogu liige Jaak Allik peab vajalikuks leida ETV-le lisamiljoneid olümpiamängude ja jalgpalli MM-i teleülekanneteks. Riigikogu liikmed Olav Aarna ja Katrin Saks kritiseerisid valitsust, et rahvusringhäälingu arengukava suhtes pole võetud seisukohta. Kultuuriminister Raivo Palmaru arvamusi. Lisa: Ringhäälingureform tulekul

  18. Himaalaja naised eesti naiste silmade läbi / Kai Herkel ; interv. Reet Varblane

    Index Scriptorium Estoniae

    Herkel, Kai

    2004-01-01

    Visuaalantropoloogiline väljapanek "Oskus olla õnnelik arenevas maailmas" Kastellaanimajas 24. märtsini. Väljas on fotod Tiibeti ja Ladakhi küladest, mägedest ja inimestest. Fotograaf Kai Herkeli, tibetoloog Natalia Munatajeva ja tiibeti munga Konchok Sangyas' kangelane on sealne naine. Piltide kõrval on suur tähtsus tekstil

  19. HBCU Equipment for AFOSR Project 13RSL012: The Mechanism by which ADP Regulates the Structure and Function of the Protein KaiC

    Science.gov (United States)

    2015-05-18

    FTE Equivalent: Total Number: Discipline Yassamin Ihat 0.00 Human biology Montana Altman 0.00 Human biology Michael Montoya 0.00 Human biology 0.00 3...cycles of day and night, because they evolved timekeeping systems called circadian clocks, which regulate biological activities with ~24- h rhythms 1...which together generate a circadian (~24 h ) rhythm of KaiC autophosphorylation, drives the clock of cyanobacteria 13, 14 . We have discovered that KaiB

  20. Rahvaliitlaste rahalaevad roostetavad kai ääres / Sten-Aleks Pihlak

    Index Scriptorium Estoniae

    Pihlak, Sten-Aleks

    2007-01-01

    Rahvaliidule lähedal seisvad ärimehed müüsid riigile maha vanu kalalaevu, et neid õppelaevadena kasutada, kuid nüüd roostetavad laevad kai ääres. Vt. samas: Lobby ekstraklass - minister tegi kõik, mis soovitud; Kalurite liit on tänaseks laiali jooksnud; Undrest jr võitles toetuse välja kohtus; Üheksast õppelaevaks muudetud alusest õpitakse päriselt vaid mõnel. Küsimustele vastab endine põllumajandusminister Ester Tuiksoo. Kommenteerivad Toivo Orgussaar ja Jüri Lember

  1. Nonindigenous marine species at Waikiki and Hawaii Kai, Oahu, Hawaii in 2001 - 2002 (NODC Accession 0001061)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Surveys of the marine algae, invertebrates and reef fishes of Waikiki and the Kuapa Pond and Maunalua Bay areas of Hawaii Kai were conducted with the objective of...

  2. Nonindigenous Marine Species at Waikiki and Hawaii Kai, Oahu, Hawaii in 2001-2002 (NODC Accession 0001061)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Surveys of the marine algae, invertebrates and reef fishes of Waikiki and the Kuapa Pond and Maunalua Bay areas of Hawaii Kai were conducted with the objective of...

  3. Tulevik on helge: noortele meeldib ettevõtlikkus / Evelin Org, Marge Rahu, Kai Isand ... [jt.

    Index Scriptorium Estoniae

    2016-01-01

    Sokos Hotels Tallinna müügi- ja turundusdirektori Evelin Orgi, kohviku Maitsvad Muffinid omaniku Marge Rahu, Garage48 SA tegevjuhi Kai Isanda, Swedbanki juriidilise divisjoni direktori Riho Roopõllu, Nortali tegevjuhi ja juhatuse liikme Andre Kulli, Veriff tegevjuhi ja asutaja Kaarel Kotkase ning Esteloni kaasasutaja ja partneri, Eesti Era- ja Riskikapitali Assotsiatsiooni tegevjuhi Kristiina Vassilkova mõtteid edukusest

  4. Spent Mushroom Waste as a Media Replacement for Peat Moss in Kai-Lan (Brassica oleracea var. Alboglabra Production

    Directory of Open Access Journals (Sweden)

    H. Sendi

    2013-01-01

    Full Text Available Peat moss (PM is the most widely used growing substrate for the pot culture. Due to diminishing availability and increasing price of PM, researchers are looking for viable alternatives for peat as a growth media component for potted plants. A pot study was conducted with a view to investigate the possibility of using spent mushroom waste (SMW for Kai-lan (Brassica oleracea var. Alboglabra production replacing peat moss (PM in growth media. The treatments evaluated were 100% PM (control, 100% SMW, and mixtures of SMW and PM in different ratios like 1 : 1, 1 : 2, and 2 : 1 (v/v with/without NPK amendment. The experiment was arranged in a completely randomized design with five replications per treatment. Chemical properties like pH and salinity level (EC of SMW were within the acceptable range of crop production but, nutrient content, especially nitrogen content was not enough to provide sufficient nutrition to plant for normal growth. Only PM (100% and SMW and PM mixture in 1 : 1 ratio with NPK amendment performed equally in terms of Kai-lan growth. This study confirms the feasibility of replacing PM by SMW up to a maximum of 50% in the growth media and suggests that NPK supplementation from inorganic sources is to ensure a higher productivity of Kai-lan.

  5. Kaasaegse Kunsti Eesti Keskus kui kunstidiiler / Rael Artel, Kai Kaljo, Marco Laimre, Marge Monko ; intervjueerinud Reet Varblane

    Index Scriptorium Estoniae

    2010-01-01

    Vestlusringis osalenud vabakutseline kuraator Rael Artel, Tallinna Ülikooli dotsent, kunstnik Kai Kaljo, EKA fotoosakonna professor, kunstnik Marco Laimre ja EKA fotoosakonna dotsent, kunstnik Marge Monko arutavad, millist rolli peaks KKEK täitma praegu, 21. sajandi teisel kümnendil avatud maailma tingimustes

  6. The Academic Profession and University Governance Participation in Japan: Focusing on the Role of Kyoju-kai

    Science.gov (United States)

    Yonezawa, Akiyoshi

    2014-01-01

    The dominant role of Kyoju-kai (the professoriate) in university governance in Japan is now facing a critical examination as part of university reforms in response to global competition. What are the determinants of the characteristics of participation in university governance by individual faculty members? In what way does the organizational…

  7. Elmut Paavel : Soomlased tulnuks Eestisse niikuinii / Elmut Paavel ; interv. Rein Raudvere

    Index Scriptorium Estoniae

    Paavel, Elmut, 1954-

    2004-01-01

    AS-i Valga Lihatööstus tegevjuht põhjendab kolmveerandi aktsiate müümist Soome suurimale lihatööstusettevõttele Atria Group Plc. Kommenteerivad: Otepää lihatööstuse Edgar juht Maie Niit ja Eesti Lihaliidu juhatuse esimees Olle Horm

  8. Designing and Implementing the Intranet for ZhuHai State-Kai Polymer and New Materials Co.,Ltd

    OpenAIRE

    Chen, Si; Jiang, Min

    2010-01-01

    This Thesis was commissioned by Zhuhai State-Kai Polymer and New Materials company, which is a chemical and pharmacy SME in China. The Thesis aimed to design and implement the Intranet with the characteristics of the case company on the basis of the identified requirements. The designed Intranet innovates in a computerized system to replace the current manual system used in its business life. The questionnaire approach was used to gather the information and requirements both from the view...

  9. Kuhu investeerida ettevõtte müügiga teenitud raha? / Peeter Raidla

    Index Scriptorium Estoniae

    Raidla, Peeter, 1955-

    2008-01-01

    Investor Rain Lõhmus ning ärimehed Elmut Paavel ja Raivo Hein räägivad oma põhimõtetest ja kogemustest ettevõtete müügist laekunud raha paigutamisel. Lisa: Valik viimaste aastate suurtehinguid. Vt. samas: Intervjuu Ambient Sound Investments tegevjuhi Tauno Tatsiga. Skype'i mehed jätkavad innovatiivselt

  10. Pertunjukan Teater Karo Hip Hop Kontemporer KAI

    Directory of Open Access Journals (Sweden)

    Silvia Anggreni Purba

    2013-11-01

    Pertunjukan Teater Karo Hip Hop Kontemporer KAI. The performance of Karo Theater collaborated with Hip Hop stems from a simple idea to collaborate Karo cultural traditions with popular culture. The performances can be enjoyed without having limitation on the language and culture. The process of combining two different cultures is a form of hybrid culture, and it may occur due to the globalization process. Through the process of deposition of the observations and strong impression, this performance is then brought into the form of Hip Hop as a preferred form which is energetic, personal and global. This performance is part of a modern tragedy with its destructive character which has explored the emotion and has presented it to the audiences. The exploration of Karo cultural tradition and Hip Hop dance as a language of symbols is able to reinforce words. The movement is not revealed by the verbal phrase but is presented through the movement of Hip Hop dance. The interpretation of the legend and texts into movement is carried out through the training process at the laboratory as a searching process and experiment, and afterward can be realized by considering the basic elements of Hip Hop, Karo cultural elements and performance. Karo Hip Hop Theatre is expected to become a preferred aesthetic form of a modern theater without losing its tradition form. Keyword: a contemporary Karo theater, Hip Hop, hybrid culture.

  11. Įvairių trąšų įtaka ekologiškai auginamiems žieminiams rugiams

    OpenAIRE

    Stelmokas, Svajūnas

    2009-01-01

    Lietuvos žemės ūkio universiteto Agroekologijos centro ekologinės gamybos ūkyje 2007-2008 m. atlikus fosforo ir kalio trąšų įtakos ekologiškai auginamiems žieminiams rugiams tyrimus nustatyta, kad didžiausias žieminių rugių derlingumas gautas tręšiant P60 fosforitmilčių norma. Didinant normą žieminių rugių derlingumas mažėjo. Lyginant fosforitmilčių normas tarpusavyje bei su netręštais žieminiais rugiais, esminių grūdų derlingumo skirtumų nenustatyta. Tręšimas fosforitmilčiais neturėjo esminė...

  12. Staphylokinase has distinct modes of interaction with antimicrobial peptides, modulating its plasminogen-activation properties

    Science.gov (United States)

    Nguyen, Leonard T.; Vogel, Hans J.

    2016-01-01

    Staphylokinase (Sak) is a plasminogen activator protein that is secreted by many Staphylococcus aureus strains. Sak also offers protection by binding and inhibiting specific antimicrobial peptides (AMPs). Here, we evaluate Sak as a more general interaction partner for AMPs. Studies with melittin, mCRAMP, tritrpticin and bovine lactoferricin indicate that the truncation of the first ten residues of Sak (SakΔN10), which occurs in vivo and uncovers important residues in a bulge region, improves its affinity for AMPs. Melittin and mCRAMP have a lower affinity for SakΔN10, and in docking studies, they bind to the N-terminal segment and bulge region of SakΔN10. By comparison, lactoferricin and tritrpticin form moderately high affinity 1:1 complexes with SakΔN10 and their cationic residues form several electrostatic interactions with the protein’s α-helix. Overall, our work identifies two distinct AMP binding surfaces on SakΔN10 whose occupation would lead to either inhibition or promotion of its plasminogen activating properties. PMID:27554435

  13. Termiškai aktyvių membraninių tekstilės medžiagų plazminis apdorojimas siekiant superhidrofobiškumo

    Directory of Open Access Journals (Sweden)

    Adam TWARDOWSKI

    2012-06-01

    Full Text Available Specialios paskirties lauko drabužiai turi atitikti aukštus patvarumo, šiluminės ištaigos ir drėgmės pernašos reikalavimus. Šiems tikslams dažnai naudojamos membraninės termiškai aktyvios tekstilės medžiagos. Siekiant pagerinti šių tekstilės medžiagų išvaizda, gali būti naudojami įvairūs poveikiai, užtikrinantys superhidrofobinį savaime besivalantį paviršių (žinomą kaip lotoso efektas. Įgyvendinant šią idėją, buvo atlikti žėrinčiojo išlydžio radijo dažnio inertinių dujų bei angliavandenilių dujų plazmos poveikio pramoninėms medžiagoms tyrimai. Gauti geri rezultatai tiriant savaiminio valymosi savybes empiriškai, tam naudojant dulkes ir kietąsias daleles. Skirtingos poveikio sąlygos buvo lyginamos matuojant kontaktinį vandens drėkinimo kampą. Daugeliu atvejų paveiktų medžiagų kontaktinis kampas buvo gerokai didesnis nei pradinių medžiagų. Didžiausia kampo vertė siekė 155°. Paviršiaus ištirtas naudojant skenuojamąjį elektroninį mikroskopą (SEM bei SEM-EDX spektroskopiją. Silikoorganinių dujų plazma apdoroto pluošto paviršiuje aptiktas plonas būdingos sferinės struktūros sluoksnis.DOI: http://dx.doi.org/10.5755/j01.ms.18.2.1920

  14. Dėl keleto retų vietovardžių kilmės (Greikónys, Grìkapėdis, Plasapnỹkai, Pušė́nai, Silgiónys, Tauliùkai, Vaĩsodžiai

    Directory of Open Access Journals (Sweden)

    Jonas Palionis

    2011-12-01

    Full Text Available ZUR ENSTEHUNG EINIGER SELTENER ORTSNAMEN (Greikónys, Grìkapėdis, Plasapnỹkai, Pušė́nai, Silgiónys, Tauliùkai, VaĩsodžiaiZusammenfassungIm vorliegenden Artikel werden sieben seltene Dorfnamen aus dem südlitauischen Gebiet behandelt. Die Analyse der Entstehung dieser Ortsnamen stützt sich vorwiegend auf das handschriftliche Material der Tauf- und Trauungsurkunden der zweiten Hälfte des 17. und der ersten Hälfte des 18. Jhs der Gemeinde Punià, die gegenwärtig dem Bezirks Alytùs angehört.Greikónys, die ältere Form ist bereits 1659 in einer Taufurkunde verzeichnet (de Gireykancow; das scheint eine Ableitung von dem Familiennamen *Gireika zu sein. Dieser Name läßt sich mit dem Verb gìrti ‘rühmen, loben’ in Verbindung setzen: *gireika- einer, der eine besondere Neigung sich zu rühmen aufweist, Prahlhans ist.Grìkapėdis ist, ohne Zweifel, ebenfalls anthroponymischen Ursprungs, da der Familienname Grìkpėdis im nordwestlichen Teil von Žemaitija vorkommt. Die Bedeutung der Komponenten dieses zusammengesetzten Familiennamens (grìkas ‘Buchweizen’ + pė́das ‘die Getreidegarbe’ zeigt eine metaphorische Basis der Entstehung des Kompositums. Die gegenwärtige Singularform ist wahrscheinlich eine spätere Bildung: in den Taufurkunden der zweiten Hälfte des 17. Jhs findet man Pluralformen (de Grikopedziow, de Grikiepedzow.Plasapnỹkai, änlich wie Greikonys und Grikapėdis, läßt ebenfalls einen anthroponymischen Ursprung vermuten, obwohl dies nicht so augenscheinlich ist. Dieser Ortsname konnte vom Familiennamen *Plasapnỹkas entstanden sein: *Plasapnỹkas < *plasa +  *upinykas, d. h. ‘ein an dem Fluß Plasãupė Wohnender’. Das erste Glied dieser kontrahierter Zusammensetzung könnte man auf eine Form des Verbs plàsti ‘breiter werden’ zurückführen.Pušė́nai kommt in der zweiten Hälfte des 17. und der ersten Hälfte des 18. Jhs als Puišėnai (de Puyszany vor. Diese ältere Form weist

  15. Enhancement of carotenoid and chlorophyll content of an edible freshwater alga (Kai: Cladophora sp. by supplementary inorganic phosphate and investigation of its biomass production

    Directory of Open Access Journals (Sweden)

    Siripen Traichaiyaporn

    2012-01-01

    Full Text Available Enhancement of the carotenoid and chlorophyll content of an edible freshwater alga (Kai:Cladophora sp. by supplementary inorganic phosphate in canteen wastewater was investigated. Themass cultivation of the alga was conducted at ambient temperature and light intensity in dilutedcanteen wastewater enhanced with dipotassium hydrogen phosphate at 5-20 mg L-1. An increase intotal carotenoid and chlorophyll was observed. However, it had no effect on biomass production. Asa result of the algal cultivation, there was a dramatic improvement in the quality of canteen wastewater.

  16. Expression of recombinant staphylokinase in the methylotrophic yeast Hansenula polymorpha

    Directory of Open Access Journals (Sweden)

    Moussa Manal

    2012-12-01

    Full Text Available Abstract Background Currently, the two most commonly used fibrinolytic agents in thrombolytic therapy are recombinant tissue plasminogen activator (rt-PA and streptokinase (SK. Whereas SK has the advantage of substantially lower costs when compared to other agents, it is less effective than either rt-PA or related variants, has significant allergenic potential, lacks fibrin selectivity and causes transient hypotensive effects in high dosing schedules. Therefore, development of an alternative fibrinolytic agent having superior efficacy to SK, approaching that of rt-PA, together with a similar or enhanced safety profile and advantageous cost-benefit ratio, would be of substantial importance. Pre-clinical data suggest that the novel fibrinolytic recombinant staphylokinase (rSAK, or related rSAK variants, could be candidates for such development. However, since an efficient expression system for rSAK is still lacking, it has not yet been fully developed or evaluated for clinical purposes. This study’s goal was development of an efficient fermentation process for the production of a modified, non-glycosylated, biologically active rSAK, namely rSAK-2, using the well-established single cell yeast Hansenula polymorpha expression system. Results The development of an efficient large scale (80 L Hansenula polymorpha fermentation process of short duration for rSAK-2 production is described. It evolved from an initial 1mL HTP methodology by successive scale-up over almost 5 orders of magnitude and improvement steps, including the optimization of critical process parameters (e.g. temperature, pH, feeding strategy, medium composition, etc.. Potential glycosylation of rSAK-2 was successfully suppressed through amino acid substitution within its only N-acetyl glycosylation motif. Expression at high yields (≥ 1g rSAK-2/L cell culture broth of biologically active rSAK-2 of expected molecular weight was achieved. Conclusion The optimized production process

  17. Chang Kai-shek's “Humanitarian Bombs” and the Mirage Known as the “Manchurian-Mongolian Problem”: New Japanese-Language Perspectives on the Transnational History of Modern East Asia

    Directory of Open Access Journals (Sweden)

    Kyu Hyun Kim

    2014-06-01

    Full Text Available On May 20, 1938, two American-made Chinese airplanes—Martin B-10 monoplane bombers—took off from Ningbo, Fujian province, in the direction of southwestern Japan. Instead of dropping bombs, they released propaganda materials produced by the Nationalist Party (Guomindang, pleading with the industrial workers, farmers, and petty bourgeois citizens of Japan to stop fighting China and resist their militarist government. This “humanitarian bombardment,” masterminded by Chiang Kai-shek, is little known today—perhaps deservedly so, for it had its embarrassing features. For one, the planes never reached the strategically important areas and merely flew over sparsely populated regions of Kumamoto and Miyazaki prefectures. Further, the propaganda materials were either voluntarily turned over to or confiscated by the Japanese authorities almost as soon as they hit the ground. As far as we can tell, the operation had little impact on the Japanese attitude toward China or on the Second Sino-Japanese War (1937–1945... Iechika Ryōko 家近亮子,Shō Kaiseki no gaikō senryaku to Nitchū sensō 蒋介石の外交戦略と日中戦争[Chiang Kai-shek's diplomatic strategies and the Sino-Japanese War]. Tokyo: Iwanami Shoten, 2012. ISBN: 978-4-00-025865-4. Nakami Tatsuo 中見立夫, 'Manmō mondai' no rekishiteki kōzu 満蒙問題の歴史的構図 [The historical composition of the “Manchurian-Mongolian problem”]. Tokyo: Daigaku Shuppankai, 2013. ISBN: 978-4-86-337131-6.

  18. The determination of multiple resistance, inheritance and cytochrome P450 activity in bifenthrinresistant Tetranychus urticae Koch (Acari: Tetranychidae)

    OpenAIRE

    AY, Recep; YORULMAZ, Sibel

    2010-01-01

    In this study, multiple resistance, inheritance and cytochrome P450 enzyme activity were determined in Tetranychus urticae Koch (SAK) population after 20 selections for bifenthrin resistance. Selection study and LC50, 60 levels of SAK population of T. urticae were determined by dry film method. LC50 level of the SAK population selected twenty times with bifenthrin was increased from 984.49 to 11914.40 µl l-1 distiled water. Selected population showing 21.84 fold resistances was named ...

  19. Effect of kai xin san on learning and memory in a rat model of paradoxical sleep deprivation.

    Science.gov (United States)

    Hu, Yuan; Liu, Ming; Liu, Ping; Yan, Juan-Juan; Liu, Ming-Yue; Zhang, Gang-Qiang; Zhou, Xiao-Jiang; Yu, Bing-Ying

    2013-04-01

    The present study aimed to evaluate the effect of kai xin san (KXS, at doses of 500, 250, and 125 mg/kg body weight per day), a well-known traditional Chinese medicine, on learning and memory in paradoxical sleep deprivation (PSD)-induced cognition deficit rats. Two behavior tests (the Open Field test and the Morris water maze task) were used for testing the effects of KXS on a PSD-induced learning and memory deficit model. Furthermore, its effect on the glutamic acid (GLU) and γ-amino-butyric acid (GABA) levels in the brain tissue, brain-derived neurotrophic factor (BDNF), cyclic AMP response element binding protein (CREB), and phosphorylated-CREB (p-CREB) expression in the hippocampus was also tested. KXS exerted the greatest cognition against the 48 h PSD-induced cognitive deficit and these effects may be mediated by decreasing the GLU and GABA levels and increasing the levels of BDNF, CREB, and p-CREB. This study indicates that the effect of KXS on learning and memory in a rat model of PSD could be associated with the modulation of neurotransmitter levels and the expression of some genes in the brain that contribute to memory functions.

  20. Pojan syntymä sielussa ja läpimurtautuminen jumaluuteen : Mestari Eckhartin käsitys jumalallisesta ykseydestä

    OpenAIRE

    Mustonen, Anni

    2011-01-01

    Tämän tutkielman tarkoituksena on tutkia mestari Eckhartin (1260 1327) ykseyden mystiikkaa. Tutkimuskysymyksiä on kaksi: (1) Miten Eckhart kuvaa käsitystään unio mysticasta? Tarkastelen kysymystä Eckhart-tutkimuksen piirissä tehdyn jaottelun mukaan, jossa unio ymmärretään joko Pojan syntymänä sielussa (saks. Geburt) ja läpimurtautumisena (saks. Durchbruch) tun-temattomaan jumaluuteen (saks. Gotheit/Gottheit). Toinen tutkimuskysymykseni on jatkumoa edelliselle ja kuuluu: (2) Millainen on Jumal...

  1. Kas teie arvates tuleks Ülejõe pargid Emajõe vasakkaldal taashoonestada? / intervjueerinud Ivi Drikkit ja Jüri Saar

    Index Scriptorium Estoniae

    2011-01-01

    Vastasid: Mati Tolmoff, Veljo Ipits, Toomas Savi, Verni Loodmaa, Väino Kull, Toomas Kapp, Triin Anette Kaasik, Kristjan Karis, Hele Everaus, Margot Fjuk, Janika Mölder, Hannes Astok, Jaak Adamsoo, Martin Parmas, Toivo Kabanen, Oleg Nesterenko, Tõnu Ints, Piret Uluots, Peep Peterson, Marju Lauristin, Jarno Laur, Arno Arukask, Ülo Veldre, Toomas Jürgenstein, Veera Sirg, Maie Pastik, Elmut Paavel, Avo Rosenvald, Toivo Maimets, Peeter Tulviste, Joel Luhamets, Jüri Kõre, Ants Kask, Enn Tarto, Tarmo Punger, Merle Jääger, Vladimir Šokman, Boris Habramov, Jevgenia Lindevaldt, Harri Jallajas, Natalja Trošina, Olev Raju, Nikolai Põdramägi

  2. The effects of pre-harvest napthalene acetic acid and aminoethoxyvinylglycine treatments on storage performance of ‘ Ak Sakı’ apple cultivar grown in Erzincan conditions

    Directory of Open Access Journals (Sweden)

    Burhan OZTÜRK

    2013-06-01

    Full Text Available This study was carried out to determine the effects of pre-harvest aminoethoxyvinylglycine (AVG, 150, 225 ve 300 mg/L and naphthaleneacetic acid (NAA, 20 mg/L treatments in different doses on storage performance of ‘Ak Sakı’ apple cultivar (Malus domestica Borkh. in 2012. The changes on some fruit quality parameters were measured at 2±1 oC temperature and with 90±5 % relative humidity at 45 days interval during storage. The lowest weight loss was obtained from 300 mg/L AVG treated fruits during the storage. In the all analysis date, the highest L* value was obtained from 300 mg/L AVG treated fruits, and the lowest hue angle value was reported from the fruits of control treatment. The flesh firmness was determined that the best kept in the 225 and 300 mg/L AVG treated fruits during the storage. The flesh firmness significantly reduced with NAA treatment at the end of storage. The highest soluble solids concentration (SSC was obtain from control fruit during the storage, whereas the lowest SSC was observed in fruit treated with 300 mg/L AVG. In the all analysis date, the highest titratable acidity was obtained in fruits treated with 225 and 300 mg/L AVG. The starch degradation was delayed with AVG treatments.

  3. Specificity of Structural Assessment of Knowledge

    Science.gov (United States)

    Trumpower, David L.; Sharara, Harold; Goldsmith, Timothy E.

    2010-01-01

    This study examines the specificity of information provided by structural assessment of knowledge (SAK). SAK is a technique which uses the Pathfinder scaling algorithm to transform ratings of concept relatedness into network representations (PFnets) of individuals' knowledge. Inferences about individuals' overall domain knowledge based on the…

  4. Environmental Violence in Minamata: Responsibility, Resistance, and Religiosity in the Case of Ogata Masato and Hongan no Kai

    Directory of Open Access Journals (Sweden)

    Yuki Miyamoto

    2018-05-01

    Full Text Available The small town of Minamata is infamous for the industrial disease named after the city. This disease resulted from having ingested methyl mercury, a substance released for more than three decades by a factory owned by the Chisso Corporation. Upon entering the human body, mercury affects the nervous system, resulting in paralysis, and often leading to a slow death. Examining how such violence was inflicted on human beings and on the environment involves a complex array of economic, environmental, and sociocultural issues, all revolving around the notions of justice and responsibility. This article analyzes the local residents’ responses to the irreparable damage done to them, focusing in particular on the thoughts and actions put forward by Ogata Masato and a group called Hongan no kai, who chose to carve bodhisattva statues. Investigating the victims’ religiosity, the author argues that the praxis put forward by the Minamata people resonates with the perspective articulated by Italian philosopher Giorgio Agamben. After having witnessed how justice had been exhausted and their case had been lost in the Japanese legal system, the victims showed their resilience in coming up with original responses, which also offer valuable insight into current discussions centered on environmental ethics.

  5. Minimal tool set for a prokaryotic circadian clock.

    Science.gov (United States)

    Schmelling, Nicolas M; Lehmann, Robert; Chaudhury, Paushali; Beck, Christian; Albers, Sonja-Verena; Axmann, Ilka M; Wiegard, Anika

    2017-07-21

    Circadian clocks are found in organisms of almost all domains including photosynthetic Cyanobacteria, whereby large diversity exists within the protein components involved. In the model cyanobacterium Synechococcus elongatus PCC 7942 circadian rhythms are driven by a unique KaiABC protein clock, which is embedded in a network of input and output factors. Homologous proteins to the KaiABC clock have been observed in Bacteria and Archaea, where evidence for circadian behavior in these domains is accumulating. However, interaction and function of non-cyanobacterial Kai-proteins as well as homologous input and output components remain mainly unclear. Using a universal BLAST analyses, we identified putative KaiC-based timing systems in organisms outside as well as variations within Cyanobacteria. A systematic analyses of publicly available microarray data elucidated interesting variations in circadian gene expression between different cyanobacterial strains, which might be correlated to the diversity of genome encoded clock components. Based on statistical analyses of co-occurrences of the clock components homologous to Synechococcus elongatus PCC 7942, we propose putative networks of reduced and fully functional clock systems. Further, we studied KaiC sequence conservation to determine functionally important regions of diverged KaiC homologs. Biochemical characterization of exemplary cyanobacterial KaiC proteins as well as homologs from two thermophilic Archaea demonstrated that kinase activity is always present. However, a KaiA-mediated phosphorylation is only detectable in KaiC1 orthologs. Our analysis of 11,264 genomes clearly demonstrates that components of the Synechococcus elongatus PCC 7942 circadian clock are present in Bacteria and Archaea. However, all components are less abundant in other organisms than Cyanobacteria and KaiA, Pex, LdpA, and CdpA are only present in the latter. Thus, only reduced KaiBC-based or even simpler, solely KaiC-based timing systems

  6. Novel mitogen-activated protein kinase MpkC of Aspergillus fumigatus is required for utilization of polyalcohol sugars.

    Science.gov (United States)

    Reyes, Guadalupe; Romans, Angela; Nguyen, C Kim; May, Gregory S

    2006-11-01

    The genome of Aspergillus fumigatus has four genes that encode mitogen-activated protein kinases (MAPKs), sakA/hogA, mpkA, mpkB, and mpkC. The functions of the MpkB and MpkC MAPKs are unknown for A. fumigatus and the closely related and genetically amenable species Aspergillus nidulans. mpkC deletion mutants of A. fumigatus were made and their phenotypes characterized. The mpkC deletion mutants were viable and had normal conidial germination and hyphal growth on minimal or complete media. This is in contrast to deletion mutants with deletions in the closely related MAPK gene sakA/hogA that we previously reported had a nitrogen source-dependent germination phenotype. Similarly, the growth of the mpkC deletion mutants was wild type on high-osmolarity medium. Consistent with these two MAP kinase genes regulating different cellular responses, we determined that the mpkC deletion mutants were unable to grow on minimal medium with sorbitol or mannitol as the sole carbon source. This result implicates MpkC signaling in carbon source utilization. Changes in mRNA levels for sakA and mpkC were measured in response to hypertonic stress, oxidative stress, and a shift from glucose to sorbitol to determine if there was overlap in the SakA and MpkC signaling pathways. These studies demonstrated that SakA- and MpkC-dependent patterns of change in mRNA levels are distinct and have minimal overlap in response to these environmental stresses.

  7. Novel Mitogen-Activated Protein Kinase MpkC of Aspergillus fumigatus Is Required for Utilization of Polyalcohol Sugars▿

    Science.gov (United States)

    Reyes, Guadalupe; Romans, Angela; Nguyen, C. Kim; May, Gregory S.

    2006-01-01

    The genome of Aspergillus fumigatus has four genes that encode mitogen-activated protein kinases (MAPKs), sakA/hogA, mpkA, mpkB, and mpkC. The functions of the MpkB and MpkC MAPKs are unknown for A. fumigatus and the closely related and genetically amenable species Aspergillus nidulans. mpkC deletion mutants of A. fumigatus were made and their phenotypes characterized. The mpkC deletion mutants were viable and had normal conidial germination and hyphal growth on minimal or complete media. This is in contrast to deletion mutants with deletions in the closely related MAPK gene sakA/hogA that we previously reported had a nitrogen source-dependent germination phenotype. Similarly, the growth of the mpkC deletion mutants was wild type on high-osmolarity medium. Consistent with these two MAP kinase genes regulating different cellular responses, we determined that the mpkC deletion mutants were unable to grow on minimal medium with sorbitol or mannitol as the sole carbon source. This result implicates MpkC signaling in carbon source utilization. Changes in mRNA levels for sakA and mpkC were measured in response to hypertonic stress, oxidative stress, and a shift from glucose to sorbitol to determine if there was overlap in the SakA and MpkC signaling pathways. These studies demonstrated that SakA- and MpkC-dependent patterns of change in mRNA levels are distinct and have minimal overlap in response to these environmental stresses. PMID:16998074

  8. Adaptors and Innovators: A Description and Measure

    Science.gov (United States)

    Kirton, Michael

    1976-01-01

    Describes development of the Kirton Adaption Innovation Inventory (KAI) for rating respondents on a continuum of adaptiveness-innovativeness, discusses tests of the validity and utility of the KAI model, and evaluates the KAI model's characteristics. For availability see EA 507 670. (Author/JG)

  9. From the Bright Future of the Nation to the Dark Future of Mankind: Jókai and Karinthy in Hungarian Utopian Tradition

    Directory of Open Access Journals (Sweden)

    Zsolt Czigányik

    2016-01-01

    Full Text Available After defining utopianism Czigányik gives a brief introduction to Hungarian utopian literature. While he discusses Tariménes utazása [‘The Voyage of Tariménes’], written by György Bessenyei in 1804, the utopian scenes of Imre Madách’s Az ember tragédiája [‘The Tragedy of Man’, 1862] and Frigyes Karinthy’s short utopian piece, Utazás Faremidoba [‘Voyage to Faremido’, 1916], the bulk of the paper deals with Mór Jókai’s monumental novel, A jövő század regénye, [‘The Novel of the Century to Come’, 1872]. Jókai, who had taken an active part in the 1848 uprising, depicts in this novel a future world of an imaginary twentieth century, where Hungary has primacy within the Habsburg empire (with the emperor king being Árpád Habsburg and the invention of the airplane (by a Hungarian brings lasting peace, stability and prosperity to the world. Besides introducing the Hungarian utopian tradition, the paper will reflect upon the role of individuals in imagined societies and how an agency-centered narrative overwrites the essentially structuralist view of history, that usually permeates utopias.

  10. Targeting the oxidative stress response system of fungi with safe, redox-potent chemosensitizing agents

    Directory of Open Access Journals (Sweden)

    Jong H. eKim

    2012-03-01

    Full Text Available The cellular antioxidation system is a target in the antifungal action of amphotericin B (AMB and itraconazole (ITZ, in filamentous fungi. The sakAΔ mutant of Aspergillus fumigatus, a mitogen-activated protein kinase (MAPK gene deletion mutant in the antioxidation system, was found to be more sensitive to AMB or ITZ than other A. fumigatus strains, a wild type and a mpkCΔ mutant (MAPK gene deletion mutant in polyalcohol sugar utilization system. The sakAΔ mutant showed no growth at 0.5 μg mL-1 of ITZ or reduced growth at 1.0 to 2.0 μg mL-1 of AMB, while the other strains exhibited robust growth. Complete fungal kill (≥ 99.9% by ITZ or AMB was achieved by much lower dosages for the sakAΔ mutant than for the other strains. SakA and MpkC appear to have overlapping roles in marshalling the oxidative stress response under treatment by an organic peroxide, tert-butyl hydroperoxide (t-BuOOH, or hydrogen peroxide (H2O2. The SakA signalling pathway was found to be responsible for fungal tolerance to AMB or ITZ toxicity. It appears msnA, an Aspergillus ortholog to Saccharomyces cerevisiae MSN2 (encoding a stress-responsive C2H2-type zinc-finger regulator and sakA and/or mpkC (upstream MAPKs are in the same stress response network under t-BuOOH-, H2O2- or AMB-triggered toxicity. Of note is that ITZ-sensitive yeast pathogens (Candida krusei and Cryptococcus neoformans were also sensitive to t-BuOOH, showing a connection between ITZ toxicity and oxidative stress response. This was shown by enhanced antifungal activity of AMB or ITZ when co-applied with redox-potent natural compounds, 2,3-dihydroxybenzaldehyde, thymol or salicylaldehyde, as chemosensitizing agents. Hence, redox compounds, which target the antioxidation system in fungi, possess a potent chemosensitizing capacity to enhance efficacy of conventional drugs inducing oxidative stress. Such chemosensitization can reduce costs and alleviate negative side effects associated with current

  11. An allele of the crm gene blocks cyanobacterial circadian rhythms.

    Science.gov (United States)

    Boyd, Joseph S; Bordowitz, Juliana R; Bree, Anna C; Golden, Susan S

    2013-08-20

    The SasA-RpaA two-component system constitutes a key output pathway of the cyanobacterial Kai circadian oscillator. To date, rhythm of phycobilisome associated (rpaA) is the only gene other than kaiA, kaiB, and kaiC, which encode the oscillator itself, whose mutation causes completely arrhythmic gene expression. Here we report a unique transposon insertion allele in a small ORF located immediately upstream of rpaA in Synechococcus elongatus PCC 7942 termed crm (for circadian rhythmicity modulator), which results in arrhythmic promoter activity but does not affect steady-state levels of RpaA. The crm ORF complements the defect when expressed in trans, but only if it can be translated, suggesting that crm encodes a small protein. The crm1 insertion allele phenotypes are distinct from those of an rpaA null; crm1 mutants are able to grow in a light:dark cycle and have no detectable oscillations of KaiC phosphorylation, whereas low-amplitude KaiC phosphorylation rhythms persist in the absence of RpaA. Levels of phosphorylated RpaA in vivo measured over time are significantly altered compared with WT in the crm1 mutant as well as in the absence of KaiC. Taken together, these results are consistent with the hypothesis that the Crm polypeptide modulates a circadian-specific activity of RpaA.

  12. From centriole biogenesis to cellular function: centrioles are essential for cell division at critical developmental stages.

    Science.gov (United States)

    Rodrigues-Martins, Ana; Riparbelli, Maria; Callaini, Giuliano; Glover, David M; Bettencourt-Dias, Monica

    2008-01-01

    Centrioles are essential for the formation of cilia, flagella and centrosome organization. Abnormalities in centrosome structure and number in many cancers can be associated with aberrant cell division and genomic instability.(1,2) Canonical centriole duplication occurs in coordination with the cell division cycle, such that a single new "daughter" centriole arises next to each "mother" centriole. If destroyed, or eliminated during development, centrioles can form de novo.(3-5) Here we discuss our recent data demonstrating a molecular pathway that operates in both de novo and canonical centriole biogenesis involving SAK/PLK4, SAS-6 and SAS-4.(6) We showed that centriole biogenesis is a self-assembly process locally triggered by high SAK/PLK4 activity that may or not be associated with an existing centriole. SAS-6 acts downstream of SAK/PLK4 to organize nine precentriolar units, which we call here enatosomes, fitting together laterally and longitudinally, specifying a tube-like centriole precursor.(7,8) The identification of mutants impaired in centriole biogenesis has permitted the study of the physiological consequences of their absence in the whole organism. In Drosophila, centrioles are not necessary for somatic cell divisions.(9,10) However, we show here that mitotic abnormalities arise in syncytial SAK/PLK4-derived mutant embryos resulting in lethality. Moreover male meiosis fails in both SAK/PLK4 and DSAS-4 mutant spermatids that have no centrioles. These results show diversity in the need for centrioles in cell division. This suggests that tissue specific constraints selected for different contributions of centrosome-independent and dependent mechanisms in spindle function. This heterogeneity should be taken into account both in reaching an understanding of spindle function and when designing drugs that target cell division.

  13. AL FIKR AL BALAGHI FI AL MA’ĂNI ‘INDA AS SAKĂKI FI KITABIHI MIFTAHUL ULUM DIRĂSAH BALAGHIYYAH

    Directory of Open Access Journals (Sweden)

    Talqis Nurdianto

    2018-02-01

    Full Text Available Miftāhul ‘Ulūm, written by al-Sakākī, especially the third part, was the beginning of a new phase in the development of Arabic rhetoric. Al-Sakākī divided the rhetoric into three fields of study, which are  (1 Ma’ānī, (2 Bayān, (3 Badī’. However, his style is influenced by philosophers, theologians and their verbal lexicon, which are difficult to take, especially for the ordinary recipient. Al-Sakākī described that his book containing several types of literature, namely, ‘ilm ṣarf in complete version and its conclusion, derivation science, and the grammatical study in the completeness of Ma’ānī and Bayān. The meaning of Makna is the study of completeness and conclusion. Therefore, books and prose, and poem require al-‘Arūḍ and al-Qawāfī include Ṣarf, Grammar, Ma’ānī, Bayān, limitation, reasoning, al’Arūḍ, and al-Qawāfī. He argued that the fields of study were influential in delivering knowledge to the student in order to reach the goal of the author towards his book.This research was an analytical descriptive study of al-Sakākī rhetoric that focused on the normative aspect represented by rhetorical rule and aesthetic aspects. Those aspects were shown by the feeling. Al-Sakākī rhetoric thought is a method based on mental division and has conducted in the construction of many factors, which the most important of them are philosophy and logic. Keywords: thought, rhetoric, meanings, sakkaki, study

  14. A Modified Chinese Herbal Decoction (Kai-Xin-San Promotes NGF-Induced Neuronal Differentiation in PC12 Cells via Up-Regulating Trk A Signaling

    Directory of Open Access Journals (Sweden)

    Lu Yan

    2017-12-01

    Full Text Available Kai-Xin-San (KXS, a Chinese herbal decoction, has been applied to medical care of depression for thousands of years. It is composed of two functional paired-herbs: Ginseng Radix et Rhizoma (GR-Polygalae Radix (PR and Acori Tatarinowii Rhizoma (ATR-Poria (PO. The compatibility of the paired-herbs has been frequently changed to meet the criteria of syndrome differentiation and treatment variation. Currently, a modified KXS (namely KXS2012 was prepared by optimizing the combinations of GR-PR and ATR-PO: the new herbal formula was shown to be very effective in animal studies. However, the cellular mechanism of KXS2012 against depression has not been fully investigated. Here, the study on KXS2012-induced neuronal differentiation in cultured PC12 cells was analyzed. In PC12 cultures, single application of KXS2012 showed no effect on the neuronal differentiation, but which showed robust effects in potentiating nerve growth factor (NGF-induced neurite outgrowth and neurofilament expression. The potentiating effect of KXS2012 was mediated through NGF receptor, tropomyosin receptor kinase (Trk A: because the receptor expression and activity was markedly up-regulated in the presence of KXS2012, and the potentiating effect was blocked by k252a, an inhibitor of Trk A. Our current results in cell cultures fully support the therapeutic efficacy of KXS2012 against depression.

  15. Kenya AIDS Indicator Surveys 2007 and 2012: implications for public health policies for HIV prevention and treatment.

    Science.gov (United States)

    Maina, William K; Kim, Andrea A; Rutherford, George W; Harper, Malayah; K'Oyugi, Boniface O; Sharif, Shahnaaz; Kichamu, George; Muraguri, Nicholas M; Akhwale, Willis; De Cock, Kevin M

    2014-05-01

    AIDS Indicator Surveys are standardized surveillance tools used by countries with generalized HIV epidemics to provide, in a timely fashion, indicators for effective monitoring of HIV. Such data should guide responses to the HIV epidemic, meet program reporting requirements, and ensure comparability of findings across countries and over time. Kenya has conducted 2 AIDS Indicator Surveys, in 2007 (KAIS 2007) and 2012-2013 (KAIS 2012). These nationally representative surveys have provided essential epidemiologic, sociodemographic, behavioral, and biologic data on HIV and related indicators to evaluate the national HIV response and inform policies for prevention and treatment of the disease. We present a summary of findings from KAIS 2007 and KAIS 2012 and the impact that these data have had on changing HIV policies and practice.

  16. A Standardized Chinese Herbal Decoction, Kai-Xin-San, Restores Decreased Levels of Neurotransmitters and Neurotrophic Factors in the Brain of Chronic Stress-Induced Depressive Rats

    Science.gov (United States)

    Zhu, Kevin Yue; Mao, Qing-Qiu; Ip, Siu-Po; Choi, Roy Chi-Yan; Dong, Tina Ting-Xia; Lau, David Tai-Wai; Tsim, Karl Wah-Keung

    2012-01-01

    Kai-xin-san (KXS), a Chinese herbal decoction being prescribed by Sun Simiao in Beiji Qianjin Yaofang about 1400 years ago, contains Ginseng Radix et Rhizoma, Polygalae Radix, Acori tatarinowii Rhizoma, and Poria. KXS has been used to treat stress-related psychiatric disease with the symptoms of depression and forgetfulness in ancient China until today. However, the mechanism of its antidepression action is still unknown. Here, the chronic mild-stress-(CMS-) induced depressive rats were applied in exploring the action mechanisms of KXS treatment. Daily intragastric administration of KXS for four weeks significantly alleviated the CMS-induced depressive symptoms displayed by enhanced sucrose consumption. In addition, the expressions of those molecular bio-markers relating to depression in rat brains were altered by the treatment of KXS. These KXS-regulated brain biomarkers included: (i) the levels of dopamine, norepinephrine, and serotonin (ii) the transcript levels of proteins relating to neurotransmitter metabolism; (iii) the transcript levels of neurotrophic factors and their receptors. The results suggested that the anti-depressant-like action of KXS might be mediated by an increase of neurotransmitters and expression of neurotrophic factors and its corresponding receptors in the brain. Thus, KXS could serve as alternative medicine, or health food supplement, for patients suffering from depression. PMID:22973399

  17. A Standardized Chinese Herbal Decoction, Kai-Xin-San, Restores Decreased Levels of Neurotransmitters and Neurotrophic Factors in the Brain of Chronic Stress-Induced Depressive Rats

    Directory of Open Access Journals (Sweden)

    Kevin Yue Zhu

    2012-01-01

    Full Text Available Kai-xin-san (KXS, a Chinese herbal decoction being prescribed by Sun Simiao in Beiji Qianjin Yaofang about 1400 years ago, contains Ginseng Radix et Rhizoma, Polygalae Radix, Acori tatarinowii Rhizoma, and Poria. KXS has been used to treat stress-related psychiatric disease with the symptoms of depression and forgetfulness in ancient China until today. However, the mechanism of its antidepression action is still unknown. Here, the chronic mild-stress-(CMS- induced depressive rats were applied in exploring the action mechanisms of KXS treatment. Daily intragastric administration of KXS for four weeks significantly alleviated the CMS-induced depressive symptoms displayed by enhanced sucrose consumption. In addition, the expressions of those molecular bio-markers relating to depression in rat brains were altered by the treatment of KXS. These KXS-regulated brain biomarkers included: (i the levels of dopamine, norepinephrine, and serotonin (ii the transcript levels of proteins relating to neurotransmitter metabolism; (iii the transcript levels of neurotrophic factors and their receptors. The results suggested that the anti-depressant-like action of KXS might be mediated by an increase of neurotransmitters and expression of neurotrophic factors and its corresponding receptors in the brain. Thus, KXS could serve as alternative medicine, or health food supplement, for patients suffering from depression.

  18. Marketingo komunikacijos priemonių naudojimas šiaulių universitete vykdomų ES struktūrinių fondų projektų pavyzdžiu

    OpenAIRE

    Gyraitė, Lina; Bivainiennė, Lina

    2008-01-01

    Straipsnyje analizuojamas marketingo komunikacijos elementų taikymas Šiaulių universitete vykdomiems ES struktūrinių fondų projektams. Marketingo komunikaciją galima apibūdinti kaip būdą, kai naudojant įvairias komunikacijos priemones, pasiekiamos numatytos tikslinės auditorijos, perduodama reikalinga informacija ir taip siekiama jas paveikti. Straipsnyje teoriškai ir praktiškai analizuojamos marketingo komunikacijos Šiaulių universitete vykdomų ES struktūrinių fondų projektų pavyzdžiu. Moksl...

  19. An application of adaption-innovation theory to bioremediation

    Energy Technology Data Exchange (ETDEWEB)

    Guerin, L.J. [World Trade Centre, Melbourne, Victoria (Australia); Guerin, T.F. [Minenco Bioremediation Services, Bundoora, Victoria (Australia)

    1995-12-31

    This paper provides a discussion of the potential application of the Kirton Adaption-Innovation Inventory (KAI) for assessing the adaptive-innovative cognitive style of individuals and organizations within the bioremediation industry. Human-resource and line managers, or other individuals responsible for staff evaluation, selection, and project planning, should consider using the KAI to assist them in selecting individuals for specific roles requiring either an innovative or adaptive style. The KAI, a measure for assessing adaption-innovation at the individual employee level, is introduced and its potential value in the bioremediation industry is discussed.

  20. Sociopato portreto vaizdavimas kinematografijoje

    OpenAIRE

    Uldukis, Vytautas

    2014-01-01

    Diplominiame darbe „Sociopato portreto vaizdavimas kinematografijoje“ nagrinėjama kaip ir kokiomis priemonėmis kino filmuose vaizduojami sociopatijos paveikti asmenys. Šis reiškinys psichologiškai dar nėra visiškai išnagrinėtas, todėl yra labai sunku visuomenėje nustatyti sociopatus. Pasireiškia tik atskiri atvejai kai jie yra demaskuojami dėl to, kad nusižengė įstatymams ir nepakluso teisėtvarkai. Nemažai įvairaus laikotarpio filmų sukuriama remiantis sociopatijos reiškiniu, kuriuose sukuria...

  1. A Cross-Validation Study of the Kirton Adaption-Innovation Inventory in Three Research and Development Organizations.

    Science.gov (United States)

    Keller, Robert T.; Holland, Winford E.

    1979-01-01

    A cross-validation study of the Kirton Adaption-Innovation Inventory (KAI) was conducted with 256 professional employees from three applied research and development organizations. The KAI correlated well with both direct and indirect measures of innovativeness in all three organizations. (Author/MH)

  2. Subunits of the Snf1 kinase heterotrimer show interdependence for association and activity.

    Science.gov (United States)

    Elbing, Karin; Rubenstein, Eric M; McCartney, Rhonda R; Schmidt, Martin C

    2006-09-08

    The Snf1 kinase and its mammalian orthologue, the AMP-activated protein kinase (AMPK), function as heterotrimers composed of a catalytic alpha-subunit and two non-catalytic subunits, beta and gamma. The beta-subunit is thought to hold the complex together and control subcellular localization whereas the gamma-subunit plays a regulatory role by binding to and blocking the function of an auto-inhibitory domain (AID) present in the alpha-subunit. In addition, catalytic activity requires phosphorylation by a distinct upstream kinase. In yeast, any one of three Snf1-activating kinases, Sak1, Tos3, or Elm1, can fulfill this role. We have previously shown that Sak1 is the only Snf1-activating kinase that forms a stable complex with Snf1. Here we show that the formation of the Sak1.Snf1 complex requires the beta- and gamma-subunits in vivo. However, formation of the Sak1.Snf1 complex is not necessary for glucose-regulated phosphorylation of the Snf1 activation loop. Snf1 kinase purified from cells lacking the beta-subunits do not contain any gamma-subunit, indicating that the Snf1 kinase does not form a stable alphagamma dimer in vivo. In vitro kinase assays using purified full-length and truncated Snf1 proteins demonstrate that the kinase domain, which lacks the AID, is significantly more active than the full-length Snf1 protein. Addition of purified beta- and gamma-subunits could stimulate the kinase activity of the full-length alpha-subunit but only when all three subunits were present, suggesting an interdependence of all three subunits for assembly of a functional complex.

  3. Populaarsemad raamatud : [Sõnum] / Ita Saks

    Index Scriptorium Estoniae

    Saks, Ita, 1921-2003

    1996-01-01

    Aasta populaarseimad raamatud läti kirjanduses: Vizma Belshevica 'Bille', Regina Ezera 'Lohe Muna' ja Karlis Levinshi 'Muinasjutujärve ääres'; populaarseimad publitsistikaraamatud on Guntis Ulmanise 'Sinult ju palju ei nõuta' ja Dainis Ivansi 'Juhuslik sõdalane'

  4. 4. VII kell 17 avatakse Haapsalu Evald Okase muuseumis rahvusvaheline klaasinäitus...

    Index Scriptorium Estoniae

    2004-01-01

    Ühtlasi lõpevad II Haapsalu klaasipäevad "Maritima". Korraldaja Kai Koppel. Klaasi puhuvad Rait Parts, Robert Tannahill Kanadast, Sun Hwan Hong Koreast, Kai Koppel. Näitusel näeb eesti klaasikunstnike Mare Saare, Ivo Lille, Rait Präätsa jt. töid

  5. Construct Validity of Three Self-Report Measures of Creativity.

    Science.gov (United States)

    Fleenor, John W.; Taylor, Sylvester

    1994-01-01

    Relations were examined among the CPI Creativity Scale (CPI-CT), the MBTI Creativity Index (MBTI-CI), and the Kirton Adaption-Innovation Inventory (KAI; a style measure of behavioral preference) for samples of 431 to 12,115 managers. KAI scores were related to CPI-CT and MBTI-CI creativity levels. (SLD)

  6. Mengukur Tingkat Kesesuaian antara Standar Akuntansi Keuangan dengan International Financial Reporting Standards per 1 Januari 2008

    Directory of Open Access Journals (Sweden)

    Rosinta Ria Panggabean

    2010-05-01

    Full Text Available International accounting topic was rare to adress between accounting practices, especially International Accounting Standard. It occured due to the restrictive source and difficulty in finding the source. However, recently the standard has been an addressed issue since Indonesia Chartered of Accountant (IAI plans to comply the Indonesia Accounting Standard (SAK with the International Financialreporting(IFRSon1stJanuary2012.The purpose of the research is to measure the compliance of the (SAK per 1st January 2008 with the IFRS per 1st January 2008 and attain the association between those two standards. Hence, the difference between the two standards and the neccessary steps to be taken for complying can be obtained. The methodology will be used in the paper are Jaccard’s Coefficients, Spearman’s Correlation Coefficient,Euclidean Distances.The sample for the paper will be 43 accounting issues adressed on both standards that have been chosen and investigated. The paper concludes that there are significant equalities (75% between SAK per 1st January 2008 and IFRS 1st January 2008. (using Jaccard’s Coefficients. Due to several problems that have been found in the research, the author wish that the further researchers could widen the research’s samples, so the result will be more accurate and comprehensive. 

  7. FY 2000 report on the results of the joint research - Field test project on the photovoltaic power generation for public facility use; 2000 nendo kyodokenkyu gyomu seika hokokusho. Kokyo shisetsu you taiyoko hatsuden field test jigyo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-05-01

    The paper arranged the FY 2000 results of the field test on the photovoltaic power generation for public facility use, etc. This report described in detail the results obtained at 237 places including the following: Social Welfare Corp. Seimei-kai, Kobe City (Hyogo Prefecture), Iitaka Town of Iinan County (Mie Prefecture), Kyushu Electric Safety Association, Educational Corp. Kongo Gakuen, Social Welfare Corp. Izumi-kai, Educational Corp. Shiobara Ikuei-kai, Educational Corp. Aiko Gakuen, Social Welfare Corp. Tachibana-kai, Cooperative Association Co-op Kobe, Social Welfare Corp. Hoshizuki-no-sato, Tochigi-Fuji Industrial Co., Hirabayashi Section of Gamo Town of Gamo County (Shiga Prefecture), Yanagawa City (Fukuoka Prefecture), Imadate City of Imadate County (Fukui Prefecture), Osaka Prefecture, Yamanashi Prefecture, Utazu Town of Ayauta County (Kagawa Prefecture), Educational Corp. Fukuyama Gakuen, New Energy Business Cooperative Association, Meitec Corp., Shikoku Medicom Co., Shizen Kobo Co., Educational Corp. Horikoshi Gakuen, Matama Town of Nishi-Kunisaki County (Oita Prefecture), Nio Town of Mitoyo County (Kagawa Prefecture), Educational Corp. Koshien Gakuin, Sansei Giken Co., Mitsui Greenland Co., AWI Mach Co., Nagoya City and Educational Corp. Kibogaoka Gakuen. (NEDO)

  8. Synergism and rules from combination of Baicalin, Jasminoidin and Desoxycholic acid in refined Qing Kai Ling for treat ischemic stroke mice model.

    Directory of Open Access Journals (Sweden)

    Jian Li

    Full Text Available Refined Qing-Kai-Ling (QKL, a modified Chinese medicine, consists of three main ingredients (Baicalin, Jasminoidin and Desoxycholic acid, plays a synergistic effect on the treatment of the acute stage of ischemic stroke. However, the rules of the combination and synergism are still unknown. Based on the ischemic stroke mice model, all different kinds of combination of Baicalin, Jasminoidin, and Desoxycholic acid were investigated by the methods of neurological examination, microarray, and genomics analysis. As a result, it confirmed that the combination of three drugs offered a better therapeutical effect on ischemic stroke than monotherapy of each drug. Additionally, we used Ingenuity pathway Analysis (IPA and principal component analysis (PCA to extract the dominant information of expression changes in 373 ischemia-related genes. The results suggested that 5 principal components (PC1-5 could account for more than 95% energy in the gene data. Moreover, 3 clusters (PC1, PC2+PC5, and PC3+PC4 were addressed with cluster analysis. Furthermore, we matched PCs on the drug-target networks, the findings demonstrated that Baicalin related with PC1 that played the leading role in the combination; Jasminoidin related with PC2+PC5 that played a compensatory role; while Desoxycholic acid had the least performance alone which could relate with PC3+PC4 that played a compatible role. These manifestations were accorded with the principle of herbal formulae of Traditional Chinese Medicine (TCM, emperor-minister-adjuvant-courier. In conclusion, we firstly provided scientific evidence to the classic theory of TCM formulae, an initiating holistic viewpoint of combination therapy of TCM. This study also illustrated that PCA might be an applicable method to analyze the complicated data of drug combination.

  9. Algasid etendustesarja "Suveaaria 2009" proovid / Silja Joon

    Index Scriptorium Estoniae

    Joon, Silja, 1966-

    2009-01-01

    10. juulist 10. augustini Pärnu Vanalinna Põhikooli õuel toimuvast Pärnu Ooperi korraldatavast etendustesarjast "Suveaaria", mille raames tuuakse installatsioon-ooperite sarjas "Kataloog" uuena välja soprani ja tenori duettide projekt "Armustseene kvaliteetooperitest" (laulavad Kai Kallastu ja Roland Liiv, etenduse lavastaja on koreograaf Kaspar Aus, kunstnik Pille Neeve, muusikalise lahenduse eest vastutavad heliloojad Andrus Kallastu ja Hans-Gunter Lock ning pianist Jorma Toots). Korratakse "Hullumisstseene kvaliteetooperitest" (esinevad sopran Kai Kallastu ja flötist Leonora Palu) ja eelmisel aastal mudaravilasse komponeeritud Locki eksperimentaalset muusikateatrietendust "Mudamuusikateraapia laboratoorium". Esitatakse Andrus Kallastu loomingul põhinev müsteerium "Valgus ja vari", milles kõlab "Stabat mater" elektroonikale, "Stabat mater" häälele (laulab Kai Kallastu, saateks Anima Mea elektroonika)

  10. El Informe Valech y la tortura masiva y sistemática como crimen contra la humanidad cometido en Chile durante el régimen militar. Su enjuiciamiento desde la perspectiva del derecho penal internacional: Apuntes a propósito de la obra del Prof. Dr. Kai Ambos, Der Allgemeine Teil des Völkerstrafrechts, 2 ed., Duncker und Humblot, Berlín 2004, 1058 páginas

    Directory of Open Access Journals (Sweden)

    Jean Pierre Matus A.

    2005-01-01

    Full Text Available En este artículo se reseña el texto del Prof. Dr. Kai Ambos, Der Allgemeine Teil des Völkerstrafrechts y, al mismo tiempo, se propone la aplicación de los principales resultados de esa obra para un eventual enjuiciamiento de la tortura masiva y sistemática aplicada en Chile entre 1973 y 1990, tal y como se describe en el Informe de la Comisión Nacional de Prisión Política y Tortura (Informe Valech. Así, se comienza describiendo y analizando la sistematización propuesta por Ambos para una parte general del derecho penal internacional, luego se analiza la tortura como crimen contra la humanidad, sujeto a las reglas del derecho penal internacional. En este apartado se determinan sus elementos principales (el carácter masivo y sistemático, el Tribunal competente en Chile para conocer de estas causas y el procedimiento aplicable. A continuación se describen los hechos, tal y como se dieron a conocer en el Informe Valech, que permiten concluir que en Chile se aplicó la tortura de manera masiva y sistemática durante el régimen militar, favorecida por éste, mediante el establecimiento de una "maquinaria" de represión "legalizada". Enseguida, se determina la existencia de una responsabilidad penal internacional individual derivada de estos hechos, para, a continuación, pasar a analizar los principales problemas de la parte general del derecho penal internacional que se presentarían en el caso de juzgarse tales responsabilidades individuales, siguiendo el esquema de análisis en dos niveles propuesto por Kai Ambos, a saber, discutiendo primero los presupuestos objetivos y subjetivos de esa responsabilidad, para finalizar analizando las principales defensas que podrían oponerse por los eventuales acusados.This article reviews Prof. Dr. Kai Ambos' book, Der Allgemeine Teil des Völkerstrafrechts, and proposes the application of the main results of this book to the possible trial of the acts of massive and systematic torture carried out

  11. 77 FR 32115 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2012-05-31

    ... Individual), Lar D. Westerberg, CEO, Application Type: Add NVO Service. Jo-Sak Shipping USA, Inc. (NVO & OFF... Service. Waterline International Logistics, Inc. (NVO & OFF), 24178 Alicia Parkway, Mission Viejo, CA...

  12. Graafika Filharmoonias : Harry Liivrand soovitab / Harry Liivrand

    Index Scriptorium Estoniae

    Liivrand, Harry, 1961-

    2004-01-01

    Alustatakse regulaarse kunstinäituse programmiga Estonia Kontserdisaalis. Avatakse graafikanäitus "Lähenemised" (koostaja Vappu Vabar). Osalevad Marje Üksine, Reti Saks, Maria-Kristiina Ulas, Kelli Kagovere, Naima Neidre jt

  13. Impact of Flight Departure Delay on Airline Choice Behavior

    Directory of Open Access Journals (Sweden)

    Taylor Tae-Hwee Lee

    2017-12-01

    Full Text Available The Korean aviation industry (KAI has been expanded significantly, because the Incheon International Airport opened in 2001 and low cost carriers (LCC entered the KAI market. But following the KAI's growth, flight departure delays (FDDs have increased six-fold during the past decade. In terms of these situations, this study firstly adds the FDD variable to an airline choice behavior (ACB model and secondly analyses how FDD impact the ACB. As a result, FDD is relatively less influential on ACB than other attributes. Both the flight service and available schedule are positively related to the choice of full service carriers (FSC. The analysis shows that FSCs’ allotment rate (AR is 85.3%, while LCCs’ one is 14.7%.

  14. Eduard Odinets : "Olen eestlane, kelle emakeel on vene keel" / Eduard Odinets ; interv. Erik Kalda

    Index Scriptorium Estoniae

    Odinets, Eduard, 1976-

    2006-01-01

    Ilmunud ka: Severnoje Poberezhje Ilmunud ka: Severnoje Poberezhje : Subbota 3. juuni lk. 3. Riigikogu sotsiaaldemokraatide fraktsiooni nõunik oma poliitikukarjäärist. Arvamust avaldab Katrin Saks ja Meelis Goldberg (Severnoje Pob.)

  15. Up regulation of K A I 1 gene expression and apoptosis effect of imatinib mesylate in gastric adenocarcinoma (AGS cell line

    Directory of Open Access Journals (Sweden)

    eyed Ataollah Sadat Shandiz

    2016-02-01

    Full Text Available Objective: To evaluate the effect of imatinib mesylate on KAI1 gene expression and apoptosis properties in human gastric carcinoma AGS cell line. Methods: Cell viability was assessed by MTT assay and quantitative real time PCR method was applied for investigation of Bax, Bcl-2, and KAI1 gene expression in AGS cells. The quantity of KAI1, Bax, and Bcl-2 compared to GAPDH gene expressions were examined using the formula 2-∆∆Ct. Furthermore, cell apoptosis/necrosis was carried out by annexin V/PI staining and quantified with flow cytometry after treatment with imatinib. Results: Imatinib mesylate was showed to have a dose-dependent toxicity effect against AGS cells. KAI1/GAPDH gene expression ratios were 1.07 ± 0.02 (P > 0.05, 1.68 ± 0.19 (P > 0.05, 3.60 ± 0.55 (P < 0.05, 6.54 ± 0.27 (P < 0.001 for 20, 50, 80 and 100 μmol/L of imatinib concentrations. The mRNA levels of Bax detected by real-time PCR after treatment with imatinib mesylate were significantly increased. Also, the number of apoptotic cells was increased from 3.72% (statistically significant; P < 0.05 in untreated AGS cells to 21.72%, 83.04% and 85.80%, respectively, following treatment with 20, 40, and 60 μmol/L imatinib mesylate. Conclusions: The results suggest that imatinib mesylate can induce apoptosis pathway in a dose-dependent mode and might modulate metastasis by up regulating KAI1 gene expression in human gastric carcinoma AGS cell line.

  16. The effects of hydrogen peroxide on the circadian rhythms of Microcystis aeruginosa.

    Directory of Open Access Journals (Sweden)

    Haifeng Qian

    Full Text Available BACKGROUND: The cyanobacterium Microcystis aeruginosa is one of the principal bloom-forming cyanobacteria present in a wide range of freshwater ecosystems. M. aeruginosa produces cyanotoxins, which can harm human and animal health. Many metabolic pathways in M. aeruginosa, including photosynthesis and microcystin synthesis, are controlled by its circadian rhythms. However, whether xenobiotics affect the cyanobacterial circadian system and change its growth, physiology and biochemistry is unknown. We used real-time PCR to study the effect of hydrogen peroxide (H(2O(2 on the expression of clock genes and some circadian genes in M. aeruginosa during the light/dark (LD cycle. RESULTS: The results revealed that H(2O(2 changes the expression patterns of clock genes (kaiA, kaiB, kaiC and sasA and significantly decreases the transcript levels of kaiB, kaiC and sasA. H(2O(2 treatment also decreased the transcription of circadian genes, such as photosynthesis-related genes (psaB, psbD1 and rbcL and microcystin-related genes (mcyA, mcyD and mcyH, and changed their circadian expression patterns. Moreover, the physiological functions of M. aeruginosa, including its growth and microcystin synthesis, were greatly influenced by H(2O(2 treatment during LD. These results indicate that changes in the cyanobacterial circadian system can affect its physiological and metabolic pathways. CONCLUSION: Our findings show that a xenobiotic can change the circadian expression patterns of its clock genes to influence clock-controlled gene regulation, and these influences are evident at the level of cellular physiology.

  17. International conference "Cultural Plurality in Estonia : Policies and Solutions"

    Index Scriptorium Estoniae

    2000-01-01

    Ettekandjad: Katrin Saks, Mall Hellam, Mati Luik, Kirsti Häkkinen, Vello Pettai, Ivi Proos, Katri Raik, NiinaOrhimenko, Ib Ostergaard Rasmussen, Urve Läänemets, Jüri Valge, Aleksander Dusman, Raivo Juurak, Rein Ruutsoo

  18. Anti-RhoC siRNAs inhibit the proliferation and invasiveness of breast cancer cells via modulating the KAI1, MMP9, and CXCR4 expression

    Directory of Open Access Journals (Sweden)

    Xu X

    2017-03-01

    Full Text Available Xu-Dong Xu,1 Han-Bin Shen,1 Li Zhu,2 Jian-Qin Lu,2 Lin Zhang,3 Zhi-Yong Luo,3 Ya-Qun Wu3 1Department of Thyroid and Breast Surgery, The Fifth Hospital of Wuhan, Hanyang District, 2Department of Oncology, 3Department of Thyroid and Breast Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China Abstract: Overexpression of RhoC in breast cancer cells indicates poor prognosis. In the present study, we aim to investigate the possible antitumor effects of anti-RhoC small-interfering RNA (siRNA in inflammatory breast cancer cells. In this study, a specific anti-RhoC siRNA was used to inhibit RhoC synthesis. Transfection of anti-RhoC siRNA into two IBC cells SUM149 and SUM190 induced extensive degradation of target mRNA and led to significant decrease in the synthesis of protein. Anti-RhoC siRNA inhibited cell proliferation and invasion, increased cell apoptosis, and induced cell cycle arrest in vitro. Moreover, the transfection of siRNA increased the expression of KAI1 and decreased the expression of MMP9 and CXCR4 in both mRNA and protein levels. Furthermore, transplantation tumor experiments in BALB/c-nu mice showed that intratumoral injection of anti-RhoC siRNA inhibited tumor growth and increased survival rate. Our results suggested that RhoC gene silencing with specific anti-RhoC siRNA would be a potential therapeutic method for metastatic breast cancer. Keywords: gene silencing, proliferation, apoptosis, cell cycle arrest

  19. Harmonisasi SAK dan Aturan Pajak: Mungkinkah?

    Directory of Open Access Journals (Sweden)

    Heri Sukendar Sukendar

    2014-11-01

    Full Text Available This paper is intended to illustrate the fact that the case today, especially in Indonesia's commitment to convergency of IFRS, where the decision was certainly not out of global importance that in order to improve the information from the financial statements of companies in Indonesia. In addition, the IFRS Convergence is one of the Indonesian government agreements as a member of the G20 forum, the results of the meeting of G20 leaders in Washington DC forum, 15 November 2008. On the other hand, the tax rules that apply are still using the old accounting standards and do not follow the development of increasingly different. Previous differences between GAAP and tax rules are limited to the "deductible and non-deductible" which is resolved through fiscal reconciliation mechanism with positive correction and correction negatipnya. The widening gap today would be a separate issue for IAI as the organization of the accounting profession. Tax Accountant compartment formation in March 2014 is a serious evidence of the organization as an anticipation, particularly in an effort to bridge the gap widening

  20. METHANE HYDRATE PRODUCTION FROM ALASKAN PERMAFROST

    Energy Technology Data Exchange (ETDEWEB)

    Richard Sigal; Kent Newsham; Thomas Williams; Barry Freifeld; Timothy Kneafsey; Carl Sondergeld; Shandra Rai; Jonathan Kwan; Stephen Kirby; Robert Kleinberg; Doug Griffin

    2005-02-01

    Natural-gas hydrates have been encountered beneath the permafrost and considered a nuisance by the oil and gas industry for years. Engineers working in Russia, Canada and the USA have documented numerous drilling problems, including kicks and uncontrolled gas releases, in arctic regions. Information has been generated in laboratory studies pertaining to the extent, volume, chemistry and phase behavior of gas hydrates. Scientists studying hydrate potential agree that the potential is great--on the North Slope of Alaska alone, it has been estimated at 590 TCF. However, little information has been obtained on physical samples taken from actual rock containing hydrates. The work scope drilled and cored a well The Hot Ice No. 1 on Anadarko leases beginning in FY 2003 and completed in 2004. An on-site core analysis laboratory was built and utilized for determining the physical characteristics of the hydrates and surrounding rock. The well was drilled from a new Anadarko Arctic Platform that has a minimal footprint and environmental impact. The final efforts of the project are to correlate geology, geophysics, logs, and drilling and production data and provide this information to scientists developing reservoir models. No gas hydrates were encountered in this well; however, a wealth of information was generated and is contained in this report. The Hot Ice No. 1 well was drilled from the surface to a measured depth of 2300 ft. There was almost 100% core recovery from the bottom of surface casing at 107 ft to total depth. Based on the best estimate of the bottom of the methane hydrate stability zone (which used new data obtained from Hot Ice No. 1 and new analysis of data from adjacent wells), core was recovered over its complete range. Approximately 580 ft of porous, mostly frozen, sandstone and 155 of conglomerate were recovered in the Ugnu Formation and approximately 215 ft of porous sandstone were recovered in the West Sak Formation. There were gas shows in the bottom

  1. Low power high growth rate deposition of microcrystalline silicon

    OpenAIRE

    Feltrin, A; Bugnon, G; Meillaud, F; Bailat, J; Ballif, C

    2008-01-01

    Microcrystalline growth regimes and solar cells obtained in different pressure and silane depletion conditions are studied in a large area KAI-S plasma reactor. The microcrystalline material quality is systematically investigated by Fourier Transform Photocurrent Spectroscopy (FTPS) to evaluate the defect density. It is shown that higher pressure and silane depletion positively affect the material quality. A clear correlation between FTPS measurements and cell efficiency is established, showi...

  2. Reval Hotel Lietuva Vilniuses : Konstitucijos pr. 20 / Piret Lindpere

    Index Scriptorium Estoniae

    Lindpere, Piret, 1963-

    2004-01-01

    Vilniuse hotelli "Lietuva" renoveerimine. Arhitektuurse projekti koostaja Rootsi arhitektuuribüroo AB SWECO (arhitektid Aare Saks, Nils Palm. Sisekujundus: Vaikla Disain AS (Katrin ja Argo Vaikla, Liis Lindvere, Peeter Loo). Kommenteerivad Argo ja Katrin Vaikla. 3 ill

  3. On Zweier Sequence Spaces and de la Vall\\'{e}e-Poussin mean of order $\\alpha$

    Directory of Open Access Journals (Sweden)

    Bipan Hazarika

    2016-07-01

    Full Text Available The main purpose of this paper is to study some geometrical properties such as order continuous, the Fatou property and the Banach-Saks property of the new space $[\\mathcal{Z}_{\\lambda}^{\\alpha}]_{\\infty}(p.$

  4. The Use of Pocket Electronic Dictionaries by Thai University Students

    Directory of Open Access Journals (Sweden)

    Atipat Boonmoh

    2011-10-01

    Full Text Available

    ABSTRACT: This article reports on a small-scale study of Thai-speaking learners using pocket electronic dictionaries (PEDs to read an English news article. It investigates how the subjects use their PEDs for reading comprehension. Thirty-nine undergraduate students completed a questionnaire survey. Of these, four were chosen to participate in the experiment. Observations and interviews were utilized to ascertain how the subjects used their PEDs. The findings showed superficial and partial reading of the dictionary entries. It also revealed several factors that may hinder dictionary look-up success. On the basis of this research, guidelines for buying PEDs and for teaching PED skills are proposed.

    OPSOMMING: Die gebruik van sak- elektroniese woordeboeke deur Thaise universiteitstudente. Hierdie artikel doen verslag van 'n kleinskaalse studie van Thaisprekende aanleerders wat sak- elektroniese woordeboeke (SEW's gebruik om 'n Engelse nuusartikel te lees. Dit ondersoek hoe die proefpersone hul SAW's gebruik vir leesbegrip. Nege-en-dertig voorgraadse studente het 'n vraelysopname voltooi. Uit hulle is vier gekies om aan die eksperiment deel te neem. Waarnemings en onderhoude is aangewend om te bepaal hoe die proefpersone hul SEW's gebruik het. Die bevindings het oppervlakkige en gedeeltelike lees van die woordeboekinskrywings getoon. Dit het ook verskeie faktore uitgewys wat woordeboekopsoeksukses mag belemmer. Op grond van hierdie navorsing word riglyne vir die koop van SEW's en vir die onderrig van SEWvaardighede voorgestel.

    Sleutelwoorde: WOORDEBOEKGEBRUIK, SAK- ELEKTRONIESE WOORDEBOEK, WOORDEBOEKRAADPLEGING, EENTALIGE WOORDEBOEK, TWEETALIGE WOORDEBOEK

  5. Targeting the Oxidative Stress Response System of Fungi with Redox-Potent Chemosensitizing Agents

    Science.gov (United States)

    Kim, Jong H.; Chan, Kathleen L.; Faria, Natália C. G.; Martins, M. de L.; Campbell, Bruce C.

    2012-01-01

    The cellular antioxidant system is a target in the antifungal action of amphotericin B (AMB) and itraconazole (ITZ), in filamentous fungi. The sakAΔ mutant of Aspergillus fumigatus, a mitogen-activated protein kinase (MAPK) gene deletion mutant in the antioxidant system, was found to be more sensitive to AMB or ITZ than other A. fumigatus strains, a wild type and a mpkCΔ mutant (a MAPK gene deletion mutant in the polyalcohol sugar utilization system). Complete fungal kill (≥99.9%) by ITZ or AMB was also achieved by much lower dosages for the sakAΔ mutant than for the other strains. It appears msnA, an Aspergillus ortholog to Saccharomyces cerevisiae MSN2 (encoding a stress-responsive C2H2-type zinc-finger regulator) and sakA and/or mpkC (upstream MAPKs) are in the same stress response network under tert-butyl hydroperoxide (t-BuOOH)-, hydrogen peroxide (H2O2)- or AMB-triggered toxicity. Of note is that ITZ-sensitive yeast pathogens were also sensitive to t-BuOOH, showing a connection between ITZ sensitivity and antioxidant capacity of fungi. Enhanced antifungal activity of AMB or ITZ was achieved when these drugs were co-applied with redox-potent natural compounds, 2,3-dihydroxybenzaldehyde, thymol or salicylaldehyde, as chemosensitizing agents. We concluded that redox-potent compounds, which target the antioxidant system in fungi, possess a chemosensitizing capacity to enhance efficacy of conventional drugs. PMID:22438852

  6. Nine Years of Cooperation: The US-German Memorandum of Understanding (MoU) on Helicopter Aeromechanics 2003-2012

    Science.gov (United States)

    2013-12-01

    qualities of side-stick controlled helicopters was given the “Ian Cheeseman Best Paper Award” at the Eu - ropean Rotorcraft Forum 2012. ii    As...Forum of the AHS, Phoenix, 2006 35    [22] Gardner, Anthony D., Richter, Kai, Rosemann, Henning : Simulation of Oscillat- ing Airfoils and Moving Flaps...Numerical Methods, 65th Annual Forum of the AHS, Grape- vine, TX, 2009 [26] Gardner, Anthony D., Richter, Kai, Rosemann, Henning : Numerical Investiga

  7. Challenges in Utilising Key Leader Engagement in Civil-Military Operations

    Science.gov (United States)

    2011-06-01

    experience from Afghanistan represented different organisations: Swedish Armed Forces (SwAF), Swedish International Development Cooperation Agency ( Sida ...with Swedish civil and military personnel • Extensive experience from several missions, focus on Afghanistan • Organisations: SwAF, Sida , SAK and

  8. Arvutijuhtimisega korter annab omanikule kontrolli / Siiri Suutre

    Index Scriptorium Estoniae

    Suutre, Siiri

    2007-01-01

    Järgmisel aastal valmib Tallinnas Juurdeveo 19 maja, kus korteriomanikel on pidev virtuaalne juurdepääs oma kodule. Projekteerijad Harry Klaar ja Kätlin Saks arhitektuuribüroost On Arhitektid. Tehnoloogiline lahendus AS Eltron ja Yoga Intelligence AS

  9. Climate change and urbanization threaten water resources in South ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2014-08-14

    Aug 14, 2014 ... JAGP: Have you found that climate-related pressures are related to ... SAK: We found that urbanization and climate change have put extra stress on water ... JAGP: Will the research team continue to work together on water ...

  10. Roles of Tunneling, Multiphoton Ionization, and Cascade Ionization for Femtosecond Optical Breakdown in Aqueous Media

    Science.gov (United States)

    2009-09-01

    This implies that a kinetic energy of Ecrit = 1.5 ~ is required for impact ionization [Kai00, Ret04]. The excess energy of 0.5  ~ that remains... Ecrit because the impact ioni- zation rate increases with kinetic energy [Arn92, Kai00, Kel60, Ret04]. To consider both factors, we assume that the...but then neglect it in their theoretical treatment of breakdown [Spa81]. The first comprehensive rate equation model including multiphoton and

  11. Root growth of Cynodon dactylon and Eleusine indica collected from motorways at different concentrations of lead.

    Science.gov (United States)

    Wong, M H; Lau, W M

    1985-04-01

    An ecological survey was conducted on the roadside vegetation at three different sites: Tai Po, a commercial and residential area (average annual daily traffic (AADT) = 23730; and Shek O and Wu Kai Sha, recreational areas (AADT = 1590 and 20, respectively). Cynodon dactylon and Eleusine indica were the two most dominant species recorded. The Tai Po site had higher Pb contents in both soil and plant, followed by Shek O, and then Wu Kai Sha. Tillers of C. dactylon and E. indica from the three sites were subjected to a series concentrations of Pb(NO3)2. By comparing their indexes of tolerance and values of 14-day EC50 (effective concentration reducing the normal root growth by 50%), roadside populations of the two grasses collected from Tai Po and Shek O, especially the former one, were more tolerant to elevated levels of Pb compared with those collected from Wu Kai Sha.

  12. A lattice calculation of the hadronic vacuum polarization contribution to (g-2)μ

    DEFF Research Database (Denmark)

    Della Morte, Michele; Francis, Anthony; Gerardin, A.

    2018-01-01

    We present results of calculations of the hadronic vacuum polarisation contribution to the muon anomalous magnetic moment. Specifically, we focus on controlling the infrared regime of the vacuum polarisation function. Our results are corrected for finite-size effects by combining the Gounaris-Sak...

  13. Expression of recombinant staphylokinase, a fibrin-specific plasminogen activator of bacterial origin, in potato (Solanum tuberosum L.) plants.

    Science.gov (United States)

    Gerszberg, Aneta; Wiktorek-Smagur, Aneta; Hnatuszko-Konka, Katarzyna; Łuchniak, Piotr; Kononowicz, Andrzej K

    2012-03-01

    One of the most dynamically developing sectors of green biotechnology is molecular farming using transgenic plants as natural bioreactors for the large scale production of recombinant proteins with biopharmaceutical and therapeutic values. Such properties are characteristic of certain proteins of bacterial origin, including staphylokinase. For many years, work has been carried out on the use of this protein in thrombolytic therapy. In this study, transgenic Solanum tuberosum plants expressing a CaMV::sak-mgpf-gusA gene fusion, were obtained. AGL1 A. tumefaciens strain was used in the process of transformation. The presence of the staphylokinase gene was confirmed by PCR in 22.5% of the investigated plants. The expression of the fusion transgene was detected using the β-glucuronidase activity assay in 32 putative transgenic plants. Furthermore, on the basis of the GUS histochemical reaction, the transgene expression pattern had a strong, constitutive character in seven of the transformants. The polyacrylamide gel electrophoresis of a protein extract from the SAK/PCR-positive plants, revealed the presence of a119 kDa protein that corresponds to that of the fusion protein SAK-mGFP-GUSA. Western blot analysis, using an antibody against staphylokinase, showed the presence of the staphylokinase domain in the 119 kDa protein in six analyzed transformants. However, the enzymatic test revealed amidolytic activity characteristic of staphylokinase in the protein extract of only one plant. This is the first report on a Solanum tuberosum plant producing a recombinant staphylokinase protein, a plasminogen activator of bacterial origin.

  14. Maintaining an outward image: a Korean immigrant's life with type 2 diabetes mellitus and hypertension.

    Science.gov (United States)

    Pistulka, Gina M; Winch, Peter J; Park, Hyunjeong; Han, Hae-Ra; Kim, Miyong T

    2012-06-01

    Type 2 diabetes mellitus (DM) and hypertension (HTN) disproportionately affect minority populations in the United States, including Korean American immigrants (KAI). We conducted qualitative interviews with middle-aged KAI in Maryland living with DM and HTN to examine the illness experience to inform future intervention strategies. Study results show that participants utilized strategies to maintain respect and Korean identity, including an image of being healthy and in control of their behavior in the public arena. These strategies included the lack of disclosure of their illness, even to family members, and avoiding outside assistance when engaging in problem solving. Maintaining an outward image of health was a common goal that affected the self-care of KAI in this study, a finding that might prove significant in the management of other chronic illnesses affecting this population. The study findings demonstrate the importance of in-depth understanding of specific populations when treating chronic illness, and caretakers' sensitivity to each population's unique cultural issues regarding identity, image, and disclosure.

  15. Relation of Knowledge and Performance in Boys' Tennis: Age and Expertise.

    Science.gov (United States)

    McPherson, Sue L.; Thomas, Jerry R.

    1989-01-01

    Examined 10- to 13-year-old boys' development of knowledge structure and sport performance in tennis by comparing skills and knowledge of experts and novices. Experts focused on higher concepts and exhibited greater decision-making ability because of their more highly developed knowledge structure. (SAK)

  16. The (temporary?) queering of Japanese TV.

    Science.gov (United States)

    Miller, S D

    2000-01-01

    One of the primary texts of the "out" queer cinema of Japan is the television serial D s kai, first aired in 1993. Unlike Western television shows positing queer characters, D s kai presents its gay characters without apology or excuses, and as leads rather than as colorful appendages. At the same time, however, the show filters gay eroticism through the (hetero)normative mode of serial melodrama, at once pushing the boundaries of national permissiveness while normalizing and homogenizing homosexuality by rendering it within a conventional form.

  17. Ebavõrdsus hukutab Eesti arengu / Katrin Saks

    Index Scriptorium Estoniae

    Saks, Katrin, 1956-

    2004-01-01

    Ilmunud ka: Pärnu Postimees, 22. jaan. 2004, lk. 11; Võrumaa Teataja, 24. jaan. 2004, lk. 2; Meie Maa, 24. jaan. 2004, lk. 2; Hiiu Leht, 27. jaan. 2004, lk. 2; Põhjarannik, 31. jaan. 2004, lk. 2; Severnoje Poberezhje, 31. jaan. 2004, lk. 2; Koit, 3. veebr. 2004, lk. 6; Hiiumaa, 3. veebr. 2004, lk. 2. Autor vaatleb riigi osa ebavõrduse ilmingute likvideerimisel Eestis ja leiab, et ebavõrdsus on meie arengu peamine takistus, mille kõrvaldamine on sotsiaaldemokraatide peamine eesmärk

  18. Kas holokaust võib korduda? / Elhonen Saks

    Index Scriptorium Estoniae

    Saks, Elhonen, 1927-

    2000-01-01

    Eestit külastas USA Kongressi Esindajatekoja välissuhete komisjoni liige Tom Lantos. Dokumentaalfilm "Viimased päevad" ("The Last Days") Eesti välisministeeriumi pressikeskuses. režissöör James Moll : Ameerika Ühendriigid 1998. Survivors of the Shoah Visual History Foundation algatus. Filmi esitusel osalesid ka L. Meri ja T. H. Ilves.

  19. Pikk tee märkamiseni / Katrin Saks

    Index Scriptorium Estoniae

    Saks, Katrin, 1956-

    2008-01-01

    Õpilaste koolisuhetest ning koolivägivallast. Ilmunud ka Vooremaa 9. okt. 2008, lk. 2 ; Võrumaa Teataja 11. okt. 2008, lk. 2 ; Koit 11. okt. 2008, lk. 6 ; Meie Maa 13. okt. 2008, lk. 2 ; Pärnu Postimees 10. okt. 2008, lk. 15 ; Virumaa Teataja 15. okt. 2008, lk. 11

  20. Äraaetud hobused lastakse maha / Katrin Saks

    Index Scriptorium Estoniae

    Saks, Katrin, 1956-

    2008-01-01

    Tööaja direktiivi muutmise eelnõust, mis suurendaks töötajate tööaja piiranguid. Ilmunud ka Põhjarannik 19. juuni 2008, lk.2 ; Vooremaa 21. juuni 2008, lk. 2 ; Virumaa Teataja 27. juuni 2008, lk. 11 ; Pärnu Postimees 27. juuni 2008, lk. 15 ; Järva Teataja 1. juuli 2008, lk. 2 ; Koit 3. juuli 2008, lk. 6 ; Nädalaleht 20. juuni 2008, lk. 7

  1. Fathers: A Placement Resource for Abused and Neglected Children?

    Science.gov (United States)

    Greif, Geoffrey L.; Zuravin, Susan J.

    1989-01-01

    Investigated 17 custodial and 18 noncustodial fathers of abused or neglected children to determine: (1) how fathers get custody; (2) how situations in which fathers get custody differ from those in which they do not; and (3) the degree to which father placements are satisfactory. (SAK)

  2. Klitika im Altpreußischen

    Directory of Open Access Journals (Sweden)

    Vytautas Rinkevičius

    2011-07-01

    Full Text Available KLITIKAI PRŪSŲ KALBOJESantraukaPrūsų kalbos III katekizmo rašyba leidžia pakankamai pagrįstai spėti, kad prūsų kalboje du kalbėjimo sraute susidūrę klitikai reguliariai sudarydavę atskirą taktinę grupę (fonologinį žodį, automatiškai kirčiuotą pirmajame skiemenyje. Reiškinys greičiausiai buvęs visiškai fonologinis ir nepriklausęs nuo semantinių ar sintaksinių grupę sudarančių žodžių ypatybių. Dėl nenuoseklios šaltinių rašybos pagrindiniu tokių taktinių grupių nustatymo kriterijumi laikytina ne tiek žodžių rašyba kartu, kiek netikėtas proklitiko kirtis. Dažniausiai tokį kirtį gauna prielinksniai konstrukcijose su vienskiemenėmis įvardžių formomis (pvz., ēnstan, tačiau lygiai taip pat gali būti paaiškintas ir jungtuko kāigi (greta kai kirčiavimas. Ne junginiuose su kitais klitikais tiek prielinksniai, tiek jungtukas kai niekada nebūna kirčiuoti. Tokie atvejai kaip prēistan klausīwingin, pērstans wāldnikans ir kt. rodo, kad klitikai sudarydavę savarankišką taktinę grupę, o ne kartu su nekirčiuotu akcentogeniniu žodžiu.

  3. Freedom in the time of oppression in L. Gutauskas’ novels “Letters from Viešvilė” and “The Feathers”

    OpenAIRE

    Bernotienė, Gintarė

    2011-01-01

    In the novels "Laiškai iš Viešvilės" ("Letters from Viešvilė") and "Plunksnos" ("The feathers") Leonardas Gutauskas considers themes of freedom and artistic creation, which in certain political situation are closely related to the problem of individual freedom and restriction of liberty in the annexed country as well. According to the metaphor of the novel "Laiškai iš Viešvilės", in the time of oppression characters live their lives as bounded by wire mesh, and despite of that freedom in this...

  4. Download this PDF file

    African Journals Online (AJOL)

    DR. AMIN

    Gadagi” tea preparations,. “sak'',”sada” and “magani”.. LD50 values of each type of the tea were determined. Results of phase. I and phase II of the study showed no mortality was recorded in any of the experimental groups of rats in 24hours ...

  5. Pärnu piirivalvekordoni hoone arhitektuurivõistlus / Hindrek Kesler

    Index Scriptorium Estoniae

    Kesler, Hindrek

    2006-01-01

    Žürii liige eskiisprojekti võistlusest ja võistlustöödest. Tulemused: II koht - töö "Arava", autor Toomas Mägi, III koht - töö "Vilgatus", autorid Kätlin Saks, Harry Klaar, ergutuspreemia - töö "Maru", autorid Heidi Urb, Siiri Vallner, Toomas Paaver

  6. Naval Research Laboratory 1986 Review

    Science.gov (United States)

    1986-01-01

    probabil- infinitesimal impedance elements cannot be dep- ity density, icted .) If PR (r. 1 is the joint probability den- sity function for r and 1, a...Dynamics. 1-5 Sept. 1986, finse Research. Medellin , Colombia. % Rosenblum, L.J., Chairperson, IEEE Computer Saks, N.S., Coorganizer and lecturer, IEEE

  7. Macroscopic modelling of solid-state fermentation

    NARCIS (Netherlands)

    Hoogschagen, M.J.

    2007-01-01

    Solid-state fermentation is different from the more well known process of liquid fermentation because no free flowing water is present. The technique is primarily used in Asia. Well-known products are the foods tempe, soy sauce and saké. In industrial solid-state fermentation, the substrate usually

  8. Simultaneous quantitation of polygalaxanthone III and four ginsenosides by ultra-fast liquid chromatography with tandem mass spectrometry in rat and beagle dog plasma after oral administration of Kai-Xin-San: application to a comparative pharmacokinetic study.

    Science.gov (United States)

    Lv, Chunxiao; Li, Qing; Zhang, Xiaowen; He, Bosai; Xu, Huarong; Yin, Yidi; Liu, Ran; Liu, Jingjing; Chen, Xiaohui; Bi, Kaishun

    2014-05-01

    A fast, selective, and quantitative ultra-fast liquid chromatography with tandem mass spectrometry method has been developed and validated for the simultaneous quantitation of polygalaxanthone III, ginsenoside Rb1, ginsenoside Rd, ginsenoside Re, and ginsenoside Rg1 in the plasma of rat and beagle dog after oral administration of Kai-Xin-San. After addition of the internal standard, salidroside, the plasma samples were extracted by liquid-liquid extraction and separated on a Venusil MP C18 column with methanol/0.01% acetic acid water as mobile phase. The tandem mass spectrometric detection was performed in the multiple reaction monitoring with turbo ion spray source in a switching ionization mode. The method was examined, and found to be precise and accurate with the linearity range of the compounds. The intra- and interday precision and accuracy of the analytes were well within acceptance criteria (±15%). The mean extraction recoveries of analytes and internal standard were all >75.0%. The validated method has been successfully applied to comparing pharmacokinetic profiles of analytes in rat and beagle dog plasma. The results indicated that no significant differences were observed in pharmacokinetic parameters of ginsenoside Rg1, while the others had significant differences, which may due to the different mechanisms of absorption and metabolism. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  9. Preoperative radiochemotherapy and radical surgery in comparison with radical surgery alone

    International Nuclear Information System (INIS)

    Mohr, C.; Schettler, D.; Bohndorf, W.

    1994-01-01

    A multicentric, randomized study of squamous cell carcinoma (SCC) of the oral cavity and the oropharynx has been undertaken by DOeSAK. The results after radical surgery alone have been compared with the results of combined preoperative radiochemotherapy followed by radical surgery. Patients with primary (biopsy proven) SCC of the oral cavity or the oropharynx with tumor nodes metastasis (TNM) stages T2-4, N0-3, M0 were included in the study. A total of 141 patients were treated by radical surgery alone, whereas 127 patients were treated by radical surgery preceded by preoperative radiochemotherapy. The pre-operative treatment consisted of conventionally fractioned irradiation on the primary and the regional lymph nodes with a total dose of 36 Gy (5 x 2 Gy per week) and low-dose cisplatin chemotherapy with 5 x 12.5 mg cisplatin per m 2 of body surface during the first week of treatment. Radical surgery according to be DOeSAK definitions (DOeSAK, 1982) was performed after a delay of 10-14 days. During the follow-up period, 28.2% of all patients suffered from locoregional recurrence, and 27.2% of the patients died. The percentages were higher after radical surgery alone for locoregional recurrence (31% and 15.6%) and for death (28% and 18.6%). The life-table analysis showed improved survival rates of 4.5% after 1 year and 8.3% after 2 years in the group of patients treated with combined therapy. The demonstrated improvement appeared to be significant with the Gehan-Wilcoxon test as well as with the log rank test below a P value of 5%. (au) (29 refs.)

  10. METHANE HYDRATE PRODUCTION FROM ALASKAN PERMAFROST

    Energy Technology Data Exchange (ETDEWEB)

    Donn McGuire; Steve Runyon; Richard Sigal; Bill Liddell; Thomas Williams; George Moridis

    2005-02-01

    Natural-gas hydrates have been encountered beneath the permafrost and considered a nuisance by the oil and gas industry for years. Engineers working in Russia, Canada and the USA have documented numerous drilling problems, including kicks and uncontrolled gas releases, in arctic regions. Information has been generated in laboratory studies pertaining to the extent, volume, chemistry and phase behavior of gas hydrates. Scientists studying hydrate potential agree that the potential is great--on the North Slope of Alaska alone, it has been estimated at 590 TCF. However, little information has been obtained on physical samples taken from actual rock containing hydrates. This gas-hydrate project is in the final stages of a cost-shared partnership between Maurer Technology, Noble Corporation, Anadarko Petroleum, and the U.S. Department of Energy's Methane Hydrate R&D program. The purpose of the project is to build on previous and ongoing R&D in the area of onshore hydrate deposition to identify, quantify and predict production potential for hydrates located on the North Slope of Alaska. Hot Ice No. 1 was planned to test the Ugnu and West Sak sequences for gas hydrates and a concomitant free gas accumulation on Anadarko's 100% working interest acreage in section 30 of Township 9N, Range 8E of the Harrison Bay quadrangle of the North Slope of Alaska. The Ugnu and West Sak intervals are favorably positioned in the hydrate-stability zone over an area extending from Anadarko's acreage westward to the vicinity of the aforementioned gas-hydrate occurrences. This suggests that a large, north-to-south trending gas-hydrate accumulation may exist in that area. The presence of gas shows in the Ugnu and West Sak reservoirs in wells situated eastward and down dip of the Hot Ice location indicate that a free-gas accumulation may be trapped by gas hydrates. The Hot Ice No. 1 well was designed to core from the surface to the base of the West Sak interval using the

  11. Benjamin Vassermanile preemiad

    Index Scriptorium Estoniae

    2007-01-01

    Graafik Benjamin Vasserman pälvis kolme digitaalse graafilise lehe eest žürii kiituse Ungaris Györis toimunud biennaalil "The Master of Drawing and Graphic Arts" ning II preemia nelja lehe eest Leedus Vilniuses toimunud VI rahvusvahelisel väikegraafika triennaalil. Eestist osalesid veel Reti Saks ja Kelli Valk

  12. Trachypodaceae. A critical revision

    NARCIS (Netherlands)

    Zanten, van B.O.

    1959-01-01

    1. Trachypus. 1. T. bicolor Reinw. et Hornsch. is divided into 4 varieties: a. var. bicolor, b. var. hispidus (C. Muell.) Card., c. var. viridulus (Mitt.) Zant. comb. nov., d. var. scindifolius (Sak.) Nog. 2. T. humilis Lindb. is divided into 2 varieties: a. var. humilis, b. var. tenerrimus (Herz.)

  13. ON STRONG AND WEAK CONVERGENCE IN n-HILBERT SPACES

    Directory of Open Access Journals (Sweden)

    Agus L. Soenjaya

    2014-03-01

    Full Text Available We discuss the concepts of strong and weak convergence in n-Hilbert spaces and study their properties. Some examples are given to illustrate the concepts. In particular, we prove an analogue of Banach-Saks-Mazur theorem and Radon-Riesz property in the case of n-Hilbert space.

  14. Kooli seksuaalhariduse mõjust Eestis / Kai Part, Kai Haldre, Eva Palm ... [jt.

    Index Scriptorium Estoniae

    2011-01-01

    Artikkel on osa UNESCO, Hollandi Radboudi ülikooli ja Tartu Ülikooli koostöös läbi viidud uurimusest, mille eesmärk oli hinnata kooli seksuaalhariduse kulusid ning mõju kuues eri elatustaseme ja geopoliitilise asendiga riigis. Käesolevas artiklis antakse ülevaade Eesti andmetest

  15. Personalikonsultant Kai Kell : ROWE-metoodika loob paindlikkuse / Kai Kell ; interv. Tiina Saar

    Index Scriptorium Estoniae

    Kell, Kai

    2008-01-01

    HR lighthouse OÜ consulting vanemkonsultant tutvustab ROWE (Results only work environment) metoodikat, mis tugineb põhimõttele, et tööd saab hinnata ainult töötulemuste järgi, ning selle rakendamise eeliseid ja puudusi ettevõtetes

  16. Bendrojo lavinimo mokyklos mokinių kiekybinis ir kokybinis mikčiojimo sunkumo įvertinimas

    OpenAIRE

    Januškevičiūtė, Deimantė

    2011-01-01

    Bakalauro darbe analizuojami išoriniai ir vidiniai mikčiojimo požymiai, mokinių požiūrio į mikčiojimą ir emocijų įvertinimo metodikos, mikčiojimo požymių įvertinimo metodikos, analizuojamas mikčiojimo sunkumo laipsnių nustatymas. Suformuluotas tyrimo tikslas, kuriuo buvo siekiama kiekybiškai ir kokybiškai įvertinti mikčiojančių mokinių užsikirtimų dažnumą, pobūdį, įvertinti lydimuosius judesius, remiantis metodiniais Mikčiojimo sunkumo metodikos (SSI) nurodymais ir atskleisti kiekybinio m...

  17. Gıda Zehirlenmeleri

    Directory of Open Access Journals (Sweden)

    Necati Akbulut

    2015-02-01

    Full Text Available Gıda Teknolojisinin gelişmesi ile, gıda maddesinin tüketici için daha alımlı olmasını sağlamak, kısa zamanda bozulmasını engellemek ve pazara yeni çeşitler sunmak için bazı kimyasal maddeler kullanılmaya başlanılmıştır. Bunun yanında tarımda kullanılan kimyasal maddeler artmış, ambalaj sanayi gelişmiş, bu da gıda maddelerine bulaşan maddelerin türlerini arttırmıştır. Ayrıca gıda maddelerine belirli amacı olmadan katılan maddelerde vardır. Diğer taraftan tüketiciyi aldatmak, hile yapmak, çok kar sağlamak veya kötü kaliteyi gizlemek amacı ile de kullanılan maddeler bulunmaktadır. İster teknik zorunluk, ister hile amacıyla olsun bu tür yabancı maddeler öncelikle insan sağlığını ilgilendirmektedir. Bazı maddelerin vücuda alınması sakıncasız olduğu halde, bazıları sakıncalıdır. Sakıncasız olanlarında belirli bir sınırın üzerinde uzun süre alınmaları zararlı olabilmektedir. Bu toplum sağlığı sorunu birçok ülkeyi gıda sanayiinde kullanılan kimyasal maddelerin hoşgörü sınırlarının hesaplanması noktasına götürmüştür.

  18. Using continuous UV extinction measurements to monitor and control the aerated phase of sequencing batch reactors; Einsatz der kontinuierlichen UV-Extinktionsmessung fuer die Ueberwachung und Regelung der Belueftungsphase in SBR-Anlagen

    Energy Technology Data Exchange (ETDEWEB)

    Nicolet, L.; Rott, U. [Stuttgart Univ. (Germany). Inst. fuer Siedlungswasserbau, Wasserguete- und Abfallwirtschaft; Bardeck, S. [Optek-Danulat GmbH (Germany)

    1999-07-01

    The work describes the measurement of UV extinction - expressed as the spectral absorption coefficient SAC - at a randomly chosen wave length as a technique for monitoring organic load in effluents from sequencing batch reactors (SBR) at municipal and industrial waste water treatment plants. Further described is to what extent the continuous determination of the SAC can be used in practice for the control of the aerated phase of sequencing batch reactors. By this means, process stabilization and optimization can be achieved and operating reliability can be enhanced. (orig.) [German] Inhalt dieses Beitrages ist es, die Messung der UV-Extinktion - ausgedrueckt durch den spektralen Absorptionskoeffizient (SAK) - bei einer frei gewaehlten Wellenlaenge als Verfahren fuer die Ueberwachung der organischen Belastung in den Ablaeufen von SBR-Anlagen (Sequencing-Batch-Reactor) in der kommunalen und industriellen Abwasserreinigung vorzustellen. Weiterhin soll dargestellt werden, in wieweit die kontinuierliche Bestimmung des SAK in der Praxis fuer die Regelung der beluefteten Phase von SBR-Anlagen eingesetzt werden kann. Hiermit kann eine Prozessstabilisierung und -optimierung der Anlagen erreicht sowie die Betriebssicherheit erhoeht werden. (orig.)

  19. Los rostros de Ana: Tres comentarios sobre Darío Morales

    Directory of Open Access Journals (Sweden)

    Paul Marcelo Velázquez Sabogal

    2016-03-01

    Full Text Available El presente escrito es una aproximación a la obra del artista colombiano Darío Morales desde la perspectiva dialéctica “vida-muerte”, alentada por el acontecimiento de lo ambiguo y sus implicaciones en la deconstrucción de una corporeidad estable regida por parámetros sociales, jurídicos y biológicos que desembocan en la caracterización de un “otro” en el cual se encuentran figuras como el anormal, el incorregible, el monstruo. Desde ellos pretendo trazar un punto de vista sobre aquellos Rostros de Ana donde se manifiestan figuras como el onanista y la vampira, para desembocar en un comentario que amplíe el espectro de sentido alrededor la obra del artista cartagenero. Palabras claves Cuerpo ambiguo, vida-muerte, sagrado-profano, onanismo. Ñawekuna kai warmi Ana Sutipa: Kimsa pariai ksi runa Dario Morales Sugllapi Kai kilkai kame ñalla regcha kai tacha runa colombiano Dario Morales Kilkakasina rimangapa “ kausai- wamui” aida chingapa kaikuna Mana allilla llugsichu tukuikunamanda icharichu llanga “sug manda” Kaipe turrerreme ¡ kauancheme man aillakaska, man allilla rurasla! Kirú. Kaipi pudenchi kauanga imasami kauacheca kai warme Ana paipa ñawekuna Kai ruraikuna sutikame onanista Chasallata vampira, Kaiwa munakume Allilla intendechengapa imasame parlaku sug iacha Cartagenero. Ima suti Rimai Simi: Cuerpo ambiguo, kaugsai, muerte, sagrado - profano, onanismo. The Faces of Ana: Three Comments on Dario Morales Abstract This paper is an approach to the work of Colombian artist Dario Morales from the perspective of the dialectic of “life and death”, encouraged by the occurrence of the ambiguous and its implications for the deconstruction of a stable corporeality governed by social, legal and biological parameters that lead to the characterization of an “other”, in which figures such as the abnormal, the incorrigible, the monster are to be found. From them, I intend to plot a point of view on those faces of Ana

  20. D : disainialfabeet / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2006-01-01

    Inglise disainerid Lucienne Day (s. 1917), Robin Day (s. 1915), Tom Dixon (s. 1959) ja ameerika disainer Henry Dreyfuss (1903-1972). Hollandi disainiajakirjast "De Stijl" ja disainirühmitusest "Droog" (asut. 1993)

  1. Experimentadesign Amsterdamis / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2008-01-01

    18.-21. septembrini 2008 toimunud rahvusvahelise disainibiennaali Experimentadesign avanädalast. Biennaali teemaks oli "Space and Place. Design for the Urban Landscape". Näitustest "Sunday Adventure Club" (kuraator Ester van de Wiel), "Droog Event 2 : Urban Play" (kuraator Scott Burnham"), "Come to My Place"

  2. H : disainialfabeet / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2006-01-01

    Tutvustatakse taani disainerit, arhitekti ja kriitikut Poul Henningseni (1894-1967), austria arhitekti ja disainerit Josef Hoffmanni (1870-1956), belgia arhitekti Victor Hortat (1861-1947), argentiina päritolu disainerit Alfredo Häberlit (sünd. 1964, Buenos Aires), Herman Milleri nimelist mööblitootmisettevõtet (asutatud 1923) USA-s, high-tech stiili

  3. C : disainialfabeet / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2006-01-01

    Andmeid disainerite kohta: Archille Castiglioni (1918-2002), Antonio Citterio (s. 1950), Luigi Colani (s. 1928), Joe Colombo (1930-1971), Terence Conran (s.1931). Briti disainerite Clare Page (s. 1975) ja Harry Richardsoni (s. 1975) firmast Committee. Cranbrooki kunstiakadeemiast USA-s

  4. Avastatud klaas / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2006-01-01

    Euroopa kõrgkoolide klaasieriala üliõpilaste tööde näitus "Discovery / Avastusretk" Kullo galeriis kuni 19. V. Rahvusvahelise ürituse korraldajaks oli EKA klaasikunsti osakond eesotsas Mare Saare ja Tiina Sarapuga. Pikemalt Ave Maseri tööst "Maandumine"

  5. V : disainialfabeet / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2007-01-01

    Tutvustatakse Edgar Velbrit arhitektina ja tema poega Teno Velbrit mööblivabriku "Standard" kauaaegse disainerina, Victoria & Alberti Muuesumi Londonis, nimekat mööblitootjat "Vitra", kelle toodangus on palju nimekate disainerite loomingut ja VHUTEMAS'i - kõrgemat kunstikooli 1920. aastail Moskvas

  6. Eesti graafika edu Hispaanias / Benjamin Vasserman

    Index Scriptorium Estoniae

    Vasserman, Benjamin

    1999-01-01

    Hispaanias Orenses dets. 1998/jaan. 1999 peetud V rahvusvahelisel graafikabiennaalil "Julio Prieto Nespereira auhind" pälvisid žürii kiituse eesti graafikud R. Saks, V. Tolli, B. Vasserman. I preemia ئ T. Uchida. Näitusel osales S. Liiva. 1998. a. sügisel Jaapanis toimunud II Tokio rahvusvahelisest väikegraafika triennaalist võttis osa N. Neidre.

  7. Toiduvilja koht pole kütusepaagis / Katrin Saks

    Index Scriptorium Estoniae

    Saks, Katrin, 1956-

    2008-01-01

    Ilmunud ka: Nädaline 22. mai, lk. 4, Pärnu Postimees 22. mai, lk. 15, Võrumaa Teataja 22. mai, lk. 2, Vooremaa 22. mai, lk. 2, Valgamaalane 22. mai lk. 2, Hiiu Leht 23. mai, lk. 2, Kuulutaja 23. mai lk. 4, Koit 24. mai lk. 6, Järva Teataja, Harju Elu 27. mai lk. 2, Vali Uudised 28. mai lk. 2, Meie Maa 29. mai lk. 2, Lääne Elu 5. juuni lk. 2, Virumaa Teataja 6. juuni, lk. 11, Sakala 6. juuni lk. 2, Molodjozh Estonii 9. juuni lk. 7. Euroopa Parlamendi liige annab ülevaate EL biokütusepoliitikast

  8. Person-environment fit: using commensurate scales to predict student stress.

    Science.gov (United States)

    Puccio, G J; Talbot, R J; Joniak, A J

    1993-11-01

    The relationship between person-environment fit and stress was examined for two samples of university students (N = 55 and 79). The Kirton Adaption-Innovation Inventory (KAI) was modified to assess the students' perceptions of the adaptor-innovator style required by their course, the styles they exhibited in the course, and their ideal style preferences. To ascertain fit, the KAI total scores and subscale scores (Originality, Efficiency, and Rule/Group Conformity) were used to classify students on three dimensions: (1) perception of what style their course required, adaptive or innovative; (2) congruence between the style the course required and the style they exhibited in the course; and (3) the magnitude of the difference, if any, between the required style and the exhibited style. Points two and three are measures of fit. The dependent variable was stress. Also the students' ideal style scores, KAI total and subscales, were substituted for the exhibited scores and the classification and analyses were repeated. Analysis of the total scores revealed that a course requiring adaptive behaviours was perceived as more stressful than a course requiring innovative behaviours. Similarly, an analysis of the Rule/Group Conformity scores revealed that the greater the conformity required the greater the stress. Also the less originality demanded in the course the greater was the perceived stress. For the KAI total scores and Rule/Group Conformity scores, the two measures of fit (incongruity and magnitude of the incongruity) were not related to stress. However, analyses of the Originality and Efficiency subscales supported the importance of the P-E fit position. For both subscales, stress was associated with the magnitude of the difference between what was required in the course and what students exhibited in the course. Educational implications derived from these findings as well as recommendations for future research are discussed.

  9. Cloning, high-level expression, purification and characterization of a ...

    African Journals Online (AJOL)

    Yomi

    2012-03-15

    Mar 15, 2012 ... sequences from S. aureus strains deposited in GenBank (AF332619, ... Metal ions and detergents also showed an inhibitory effect on rSak, especially Zn2+ and Cu2+ which .... at 6000 rpm for 10 min at 4°C. Wet cells was used immediately for .... 42% of the total proteins (Figure 2A, lanes 3 to 5) using.

  10. Can commercial surrogacy be equated to human trafficking?

    OpenAIRE

    Monstytė, Evelina

    2014-01-01

    Surogaciją būtų galima įvardinti viena iš seniausių prekybos žmonėmis, taip pat ir vaikais, formų. Nors dauguma žmonių mano, jog surogacija yra medicinos naujovė, iš tikro šis būdas buvo žinomas dar Biblijos laikais.Didžiausias lūžis medicinoje, po kurio surogacija tapo plačiai naudojama procedūra, įvyko 1978 m. liepos 25 dieną, kai gimė pirmasis kūdikis, kuris buvo pradėtas mėgintuvėlyje. Ši technologija suteikė galimybę nevaisingoms poroms susilaukti genetiškai su jais susijusio vaiko. Taip...

  11. Scientific Creativity and High Ability: Gender and academic level differences

    Directory of Open Access Journals (Sweden)

    Fernando Javier ESPARZA MOLINA

    2015-10-01

    Full Text Available  The purpose of this study was to investigate the influence of gender and educational level on scientific creativity among gifted/talented students. A cohort of creatividad científica y alta habilidad: diferencias de género y nivel educativo 78 secondary school students from 12 to 16 years old participated in this research. The scientific creativity was measured using the Creative Scientific Ability Test (Sak & Ayas, 2011 designed for secondary school students from 11 to 14 years old. Its theoretical framework sets up the measurement of a three dimensional structure: general creative abilities (fluency, flexibility and creativity, scientific creative abilities (hypothesis generation, hypothesis testing and evidence evaluation and scientific knowledge. This test has the right adequate psychometric properties with a Cronbach’s alpha coefficient of 0.848 (Sak & Ayas, 2013. Results indicated that male students scored significantly higher in a task named Interaction Graph which measures hypothesis generation in interdisciplinary science. The analysis also showed that students involved in upper education levels scores significantly higher in general fluency and in the task called The Food Chain which measures evidence evaluation in the area of ecology.

  12. Purification and characterization of the three Snf1-activating kinases of Saccharomyces cerevisiae.

    Science.gov (United States)

    Elbing, Karin; McCartney, Rhonda R; Schmidt, Martin C

    2006-02-01

    Members of the Snf1/AMPK family of protein kinases are activated by distinct upstream kinases that phosphorylate a conserved threonine residue in the Snf1/AMPK activation loop. Recently, the identities of the Snf1- and AMPK-activating kinases have been determined. Here we describe the purification and characterization of the three Snf1-activating kinases of Saccharomyces cerevisiae. The identities of proteins associated with the Snf1-activating kinases were determined by peptide mass fingerprinting. These kinases, Sak1, Tos3 and Elm2 do not appear to require the presence of additional subunits for activity. Sak1 and Snf1 co-purify and co-elute in size exclusion chromatography, demonstrating that these two proteins form a stable complex. The Snf1-activating kinases phosphorylate the activation loop threonine of Snf1 in vitro with great specificity and are able to do so in the absence of beta and gamma subunits of the Snf1 heterotrimer. Finally, we showed that the Snf1 kinase domain isolated from bacteria as a GST fusion protein can be activated in vitro and shows substrate specificity in the absence of its beta and gamma subunits.

  13. Segadus ravimite hinna ümber / Piret Sell

    Index Scriptorium Estoniae

    Sell, Piret

    2005-01-01

    Oma vastulauses 12. detsembri Eesti Päevalehes ilmunud Kai Kalamehe artiklile "Mitmete ravimite hind tõuseb" selgitab autor ravimite hinnatõusu ning seda, miks on originaalravimid kallimad kui koopiaravimid

  14. Peasant struggles and social change: migration, households and gender in a rural Turkish society.

    Science.gov (United States)

    Ilcan, S M

    1994-01-01

    "This article sheds light on the interrelationship of seasonal migration, subsistence production and peasant relations in a community (Sakli) located in Turkey's northwestern countryside.... While migrant labor is understood by local villagers as forming part of a continual battle to preserve local tradition and kinship ties, this article shows how it reduces the dominion of landlords while creating internal household differentiation and gendered hierarchies." excerpt

  15. Eesti disain / Silvia Pärmann

    Index Scriptorium Estoniae

    Pärmann, Silvia

    2014-01-01

    Ahti Grünbergi ja Tõnis Kalve mööbliseeria Derelict. Maile Grünbergi disainitud toolid ja laud Madis. Taniel Kolpakovi kaubamärgile Rough Bloom disainitud köögimööbel. Kaubamärgi Varm Country uus kollektsioon Basic no 2. Kersti Laanmaa keraamilised teekannud Kiviaeg ja Jänes kapsas. Tiina Mangi kavandatud diivan Sik-Sak. Tõnis Vellama valgustimudel AET27

  16. Kaisi kimbutav õlavalu sundis eestlasi turniiri katkestama / Ann Hiiemaa

    Index Scriptorium Estoniae

    Hiiemaa, Ann

    2007-01-01

    Nädal tagasi maailmameistrivõistlustelt viienda koha rannavõrkpallurid Kristjan Kais ja Rivo Vesik olid Kaisi õlavalu tõttu sunnitud Austrias Klagenfurtis toimuva Grand Slami etapi pooleli jätma

  17. The pathway by which the yeast protein kinase Snf1p controls acquisition of sodium tolerance is different from that mediating glucose regulation.

    Science.gov (United States)

    Ye, Tian; Elbing, Karin; Hohmann, Stefan

    2008-09-01

    It recently became apparent that the highly conserved Snf1p protein kinase plays roles in controlling different cellular processes in the yeast Saccharomyces cerevisiae, in addition to its well-known function in glucose repression/derepression. We have previously reported that Snf1p together with Gis4p controls ion homeostasis by regulating expression of ENA1, which encodes the Ena1p Na(+) extrusion system. In this study we found that Snf1p is rapidly phosphorylated when cells are exposed to NaCl and this phosphorylation is required for the role of Snf1p in Na(+) tolerance. In contrast to activation by low glucose levels, the salt-induced phosphorylation of Snf1p promoted neither phosphorylation nor nuclear export of the Mig1p repressor. The mechanism that prevents Mig1p phosphorylation by active Snf1p under salt stress does not involve either hexokinase PII or the Gis4p regulator. Instead, Snf1p may mediate upregulation of ENA1 expression via the repressor Nrg1p. Activation of Snf1p in response to glucose depletion requires any of the three upstream protein kinases Sak1p, Tos3p and Elm1p, with Sak1p playing the most prominent role. The same upstream kinases were required for salt-induced Snf1p phosphorylation, and also under these conditions Sak1p played the most prominent role. Unexpectedly, however, it appears that Elm1p plays a dual role in acquisition of salt tolerance by activating Snf1p and in a presently unknown parallel pathway. Together, these results indicate that under salt stress Snf1p takes part in a different pathway from that during glucose depletion and this role is performed together as well as in parallel with its upstream kinase Elm1p. Snf1p appears to be part of a wider functional network than previously anticipated and the full complexity of this network remains to be elucidated.

  18. Augalų, auginamų žaliajai trąšai, agrobiologinis įvertinimas ir įtaka svogūnų derliui

    OpenAIRE

    Starkutė, Roma; Duchovskienė, Laisvūnė; Zalatorius, Zytautas

    2006-01-01

    2003–2005 m. Lietuvos sodininkystės daržininkystės institute ekologiškai daržovėms auginti skirtame bandymų lauke tirti ir įvertinti žaliajai trąšai tinkamiausi augalai ir nustatyta jų įtaka ekologiškai auginamų svogūnų derliui. Tirti augalai žaliajai trąšai: miežiai, miežiai su dobilų įsėliu, vasariniai kviečiai, žirnių ir avižų mišinys, aliejiniai ridikai. Kontrolinis variantas – juodasis pūdymas. Nustatyta, kad žaliajai trąšai auginamų augalų biomasė armenyje paliko nevienodą organinės med...

  19. Vanemuislaste ballett astub uude kümnesse / Raimu Hanson

    Index Scriptorium Estoniae

    Hanson, Raimu, 1957-

    2009-01-01

    Vanemuise balleti ajaloost, 4. märtsil 1939. aastal toimunud esietendusest, tänasest teatri balletitrupist. Juubeliks ilmunud raamatust ja DVD-st "Vanemuise ballett 70", koostajad Mare Tommingas ja Kai Kangur

  20. Pateetiline kukkumine XXI sajandisse / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-

    2000-01-01

    Tartu Kunstimajas ja monumentaalgaleriis avatud Reet Varblase kureeritud näitusest "Eneseksjäämine. Väikesed rollimängud XXI sajandiks". Pikemalt Terje Ojaveri performance'ist, Kai Kaljo videost "Pateetika"

  1. Eesti ajalugu Vene-Liivimaa sõjast Põhjasõjani / Lea Kõiv

    Index Scriptorium Estoniae

    Kõiv, Lea, 1961-

    2014-01-01

    Arvustus: Enn Küng, Margus Laidre, Ivar Leimus, Aivar Põldvee, Anti Selart, Marten Seppel, Kai Tafenau, Ülle Tarkiainen, Enn Tarvel. Eesti ajalugu III: Vene-Liivimaa sõjast Põhjasõjani. Tartu, 2013

  2. Kultuurkapitali preemiad

    Index Scriptorium Estoniae

    2000-01-01

    Eesti Kultuurkapitali aastapreemia U. Lippusele, Helikunsti aastapreemiad J. Leitenile, M. Martinile, J. Reinverele, V. Sarvele, A. Volmerile, Uus Tallinna Triole, Duole Kai Ratassepp, Mati Mikali; Rahvakultuuri Sihtkapitali aastapreemia J. Rent, V. Sarv

  3. Avatud arhiiv / Ketli Tiitsar

    Index Scriptorium Estoniae

    Tiitsar, Ketli

    2005-01-01

    Näitus "Arhiiv. Tarbekunstimuuseumi näitused 1982-2004" Eesti Tarbekunsti- ja Disainimuuseumis kuni 15. I 2006. Näituse on koostanud Merike Alber, Kai Lobjakas, Airi Ligi, Anne Tiivel, kujundanud Ketli Tiitsar

  4. Baltikumi meediakunst Dortmundis / Raivo Kelomees

    Index Scriptorium Estoniae

    Kelomees, Raivo, 1960-

    2006-01-01

    Balti kultuurifestivalist "scene: estland lettland litauen in nrw" Dortmundi Ostwall-muuseumis. Eestit esindavad oma töödega Kai Kaljo, Mark Raidpere, Jaan Toomik, Tiia Johannson, Killu Sukmit, Mari Laanemets, Raivo Kelomees

  5. Riskikapital vajab riigi kehtestatud mängureegleid / Peeter Saks

    Index Scriptorium Estoniae

    Saks, Peeter

    2004-01-01

    AS-i Suprema Securities juhatuse esimehe sõnul on Euroopa riskikapitali turul selge nõudlus sobiva seadusliku raamistiku ja hea mainega riigi või piirkonna järele, Eestil on praegu võimalus kujuneda Euroopa üheks riskikapitali keskuseks. Autori arvates peaks esimeseks sammuks olema eraldi riskikapitali seaduse loomine. Vt. samas: Andrus Ansip, Taavi Veskimägi ja Linnar Viik vastavad küsimusele, kas Eesti vajab riiklikku riskikapitali fondi

  6. Valitsusliit jätab lasteaiaõpetajad virelema / Katrin Saks

    Index Scriptorium Estoniae

    Saks, Katrin, 1956-

    2004-01-01

    Koolieelsete lasteasutuste seaduse muutmise seaduseelnõu hääletati Riigikogu menetlusest välja, vanemahüvitistest. Ilmunud ka Pärnu Postimees 23. sept. 2004, lk. 15 ; Hiiu Leht 24. sept. 2004, lk. 2 ; Sakala 24. sept. 2004, lk. 2 ; Vali Uudised 24. sept. 2004, lk. 2 ; Nädaline 23. sept. 2004, lk. 4 ; Põhjarannik 24. sept. 2004, lk. 2 ; Türi Rahvaleht 24. sept. 2004, lk. 4, Meie Maa 28. sept. 2004. lk. 2 ; Koit 30. sept. 2004, lk. 6 ; Vooremaa 7. okt. 2004, lk. 2 ; Valgamaalane 16. okt. 2004, lk. 2

  7. Laste hulk ei sõltu toonekurgede arvukusest / Katrin Saks

    Index Scriptorium Estoniae

    Saks, Katrin, 1956-

    2006-01-01

    Perekonnaseaduse eelnõust ja samasooliste abielust. Sama ka Harjumaa 24. jaan. 2006, lk. 2 ; Võrumaa Teataja 24. jaan. 2006, lk. 2 ; Vali Uudised 25. jaan. 2006, lk. 2 ; Meie Maa 25. jaan. 2006, lk. 2 ; Hiiu Leht 27. jaan. 2006, lk. 2 ; Kuulutaja 27. jaan. 2006, lk. 4 ; Lõunaleht 26. jaan. 2006, lk. 2 ; Vooremaa 26. jaan. 2006, lk. 2 ; Pärnu Postimees 2. veeb. 2006, lk. 11 ; Sakala 2. veeb. 2006, lk. 2 ; Valgamaalane 25. aprill 2006, lk. 2 ; Hiiu Leht 9. mai 2006, lk. 2 ; Sotsiaaldemokraat 16. veeb. 2006, lk. 5

  8. KUALITAS LAPORAN KEUANGAN UMKM SERTA PROSPEK IMPLEMENTASI SAK ETAP

    Directory of Open Access Journals (Sweden)

    Rizki Rudiantoro

    2012-06-01

    Full Text Available This study examines the effect of quality of the SMEs’ financial statements on level of credit received by SMEs, as well as prospect of financial accounting standard for entity without public accountability (FAS EWPA implementation in 2011 to improve the quality of the financial statements of SMEs. The data of this study is obtained from the questionnaires returned by 50 SME entrepreneurs in the area of Jakarta, Bogor, Depok, and other parts of Java. The results of this study show that the quality of SME financial statements do not affect the amount of credit received by SMEs. This may be due to the low quality of financial statements of SMEs so that banks are still in doubt with the relevancy and reliability of financial reporting. Prospect of FAS EWPA implementation to improve the quality of financial report may have been constrained due to the low understanding of the SME entrepreneurs over the FAS EWPA.

  9. Differential expression patterns of metastasis suppressor proteins in basal cell carcinoma.

    Science.gov (United States)

    Bozdogan, Onder; Yulug, Isik G; Vargel, Ibrahim; Cavusoglu, Tarik; Karabulut, Ayse A; Karahan, Gurbet; Sayar, Nilufer

    2015-08-01

    Basal cell carcinomas (BCCs) are common malignant skin tumors. Despite having a significant invasion capacity, they metastasize only rarely. Our aim in this study was to detect the expression patterns of the NM23-H1, NDRG1, E-cadherin, RHOGDI2, CD82/KAI1, MKK4, and AKAP12 metastasis suppressor proteins in BCCs. A total of 96 BCC and 10 normal skin samples were included for the immunohistochemical study. Eleven frozen BCC samples were also studied by quantitative real time polymerase chain reaction (qRT-PCR) to detect the gene expression profile. NM23-H1 was strongly and diffusely expressed in all types of BCC. Significant cytoplasmic expression of NDRG1 and E-cadherin was also detected. However, AKAP12 and CD82/KAI1 expression was significantly decreased. The expressions of the other proteins were somewhere between the two extremes. Similarly, qRT-PCR analysis showed down-regulation of AKAP12 and up-regulation of NM23-H1 and NDRG1 in BCC. Morphologically aggressive BCCs showed significantly higher cytoplasmic NDRG1 expression scores and lower CD82/KAI1 scores than non-aggressive BCCs. The relatively preserved levels of NM23-H1, NDRG1, and E-cadherin proteins may have a positive effect on the non-metastasizing features of these tumors. © 2014 The International Society of Dermatology.

  10. Auriga kaubanduskeskus Saaremaal = Auriga shopping centre, Saaremaa

    Index Scriptorium Estoniae

    2009-01-01

    Saaremaal Kudjape külas Tallinna t. 88 asuva Auriga kaubanduskeskuse sisekujundusest. Sisearhitektid Liina Saabas ja Kai Laanmets. Arhitekt Eero Palm. Sisearhitektide tähtsamate ühiselt tehtud tööde loetelu

  11. Tartu Keskkonnahariduse Keskuse Loodusmaja = Nature School of Tartu Environmental Education Centre

    Index Scriptorium Estoniae

    2015-01-01

    Tartu Keskkonnahariduse Keskuse Loodusmaja Lille tänav 10, valminud 2013. Arhitektuurivõistlus 2010. Arhitektid Martin Kinks, Risto Parve, Kai Süda, Margit Valma (Karisma Arhitktid), Diana Taalfeld (NU Arhitektuur). Sisearhitekt Tõnis Kalve

  12. Installation Restoration Program. Site Investigation Report. 147th Fighter Interceptor Group, Texas Air National Guard, Ellington, Field, Houston, Texas

    Science.gov (United States)

    1991-01-01

    N4.L.....-I~C1 01AME TER ...... SACKS OF TON’O 4-1At AN SCH4EDULE 40PVC SAK pTA rEINO 8LANK VLT TRAP I o GALLONS OF GVOUT USED SOTTOM WELL CAP POUNDS...and fungi on leaf surfaces and in soil. Many of these microorganisms play key roles in the decomposer food chain. Cases of lead poisoning have been

  13. AS Balti Ameerika Auto Keskus Peterburi tee 50

    Index Scriptorium Estoniae

    1998-01-01

    Tallinna 'Chrysleri' ja 'Jeepi' autokeskuse hoonekompleksis on eristatavad kolm osa: kahekorruseline müügisalong, ühekorruseline töökoda ja hooldusruunid, ladu ning olmeplokk. Klaasfassaadiga automüügisaal ulatub hoonest välja sammastega ümbritsetud poolkaarest paadikujulise siiluna. Peatöövõtja: AS Feer Ehituse projektijuht: AS TSM. Projekteerija: Arhitektuuribüroo R. Puusepp. Arhitekt Aare Saks (FFNS, Rootsi). Sisekujundus Rein Nurmse. Projekt 1996, valmis 1997

  14. President 2001 / interv. Kai Kalamees

    Index Scriptorium Estoniae

    2001-01-01

    Eesti Päevaleht palus erinevate elualade esindajatel hinnata presidendikandidaatide ametisse sobivust (Savi, Tarand, Kelam, Kreitzberg, Tulviste). Vastavad: Aivar Voog, Rein Ruutsoo, Kaur Hanson, Ivo Rull, Tarmo Tammerk, Mart Helme, Pavel Ivanov, Jaan Kaplinski. Diagrammid

  15. Vormistatud ruumid 2010 / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2011-01-01

    Eesti Sisearhitektide Liidu 2010. a. preemia saanud töödest. Söögikoha interjööri preemia: kohvik Supelsaksad Pärnus (Ruth, Jaak ja Anna Huimerind), ühiskondliku interjööri preemia: ADM Interactive'i büroo Tallinnas (Tomomi Hayashi, Ahti Grünberg, Kerli Valk), ajaloolise interjööri preemia: Kihnu muuseum (Malle Jürgenson, Tea Tammelaan, Krista Lepland, Jaak Huimerind, Indrek Laos), näituse- ja installatsiooni kujunduse preemia: rändnäitus "Eesti kirjanik karikatuuris" (Janno Siimar, Kaarel Vahtramäe, Mart Lankots, Liina Jakobson), tudengipreemia - Aet Tera

  16. Ujuv restoran Portos / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    1999-01-01

    Tegu on terasest ja kolmest küljest klaasist kuubikuga, mis asetseb ankrus olevale ujuvalusele paigutatud puitplatvormil Duoro jõel. Kaldast on restoran eraldatud puitseintega, mille ees olev metalltala toetab katust. Autor G. P. Couto.

  17. Jõulujazz alustab heaga / Kai Ilustrumm

    Index Scriptorium Estoniae

    Ilustrumm, Kai

    2004-01-01

    Heategevuskontserdist "Aita alustada elu!" Kaarli kirikus 28. nov., Soome multiinstrumentalisti Sakari Kukko trio kontserdist 5. dets. Niguliste muuseum-kontserdisaalis, ameerika vokaalansambli M-Pact kontserdist 7. dets. Pärnu kontserdimajas, Raivo Tafenau-Meelis Vindi koosmusitseerimisest tšiili löökpillimängija Ricardo Padillaga 11. dets. Niguliste muuseum-kontserisaalis, Helin-Mari Arderi kontserdist "Sajab esimest lund" 15. dets. Niguliste muuseum-kontserisaalis, rootsi ansambli Bossa Electrica esinemiset 16. dets. Rock Café's, ansambli Eesti Keeled kontserdist "Vaiksel ööl" 17. dets. Tallinnas Sokos Hotell Virus

  18. Kindluselamud Lebbekes, Belgias / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    1999-01-01

    Sotsiaalehitistena tellitud Lebbeke neli uut maja näevad välja nagu hästikindlustatud eramud. 1,7 meetri kõrguste tellismüüridega suletud alade sees asuvad autovarjualune, aiakuur, terrass ja aed, mis on klaasseina abi ühenduses maja alumise korrusega. Materjalid: tellis, tumehall metall, betoon. Autor: Bob 361 Arhitektid.

  19. R : disaini alfabeet / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2007-01-01

    Tutvustatakse Ameerika graafilise disaini euroopalikumaks muutjat Paul Rand'i, sisearhitekti Toivo Raidmetsa, rahvusvahelise taustaga disainerit Karim Rashid'i, keraamikut ja pedagoogi Leo Rohlinit ja kunsti radikaalseks uuendamiseks asutatud rühmituse (1917.a.) De Stijl üht hilisemat liiget Gerrit Rietveldi

  20. Eesti disaini uudised / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2006-01-01

    Eesti Kunstiakadeemia üliõpilaste Kadri Kruus-Laurimaa kott-jope, Riho Tiiveli lusikas "Spoon container" ja Ülle Jehe sisustuspadjad "Roll it!" valiti Prantsusmaal toimunud rahvusvahelisel kunsti-ja disainikõrgkoolide võrgustiku CUMULUS konkursil "European Ways of Life" nominentide hulka. EKA sisearhitektuuri eriala üliõpilaste toolide hindamisest. Mari Adamsoni nimelise noore tekstiilikunstniku preemia pälvis Kadri Klampe. Eesti Ajaloomuuseumis Maarjamäe lossis avatud moenäitusest "Paula, sul on poisipea!", mille koostas Helle Avila, konsulteeris Anu Ojavee, kujundasid Krista Lepland ja Malle Jürgenson büroost Laika, Belka ja Strelka

  1. Tulevikulinna esimene maja / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    1999-01-01

    Santiago Calatrava juhtimisel valminud esimene ehitis Valencias asuvas nn. 'teaduste ja kunsti linnas'. 'Hemisfääriks' kutsutav hoone on betoonist, klaasist ja võrevormis terasest. Ka 'tarkusesilmaks' kutsutav ehitis asetseb ristkülikukujulise veekogu keskel. S. Calatravalt on tellitud 'linna' kolm peahoonet. Okeanograafilise pargi kujundab Félix Candela

  2. "Central Station" Londonis

    Index Scriptorium Estoniae

    2000-01-01

    Londoni galeriis Milch seitsme läti, leedu ja eesti kunstniku projekt "Central Station". Kuraatorid Lisa Panting, Sally Tallant. Eestist osalevad Hanno Soans (Catarina Campinoga koostöös valminud video), Kiwa, Kai Kaljo

  3. Promoting better integration of health information systems: best practices and challenges

    NARCIS (Netherlands)

    Michelsen, K.; Brand, H.; Achterberg, P.; Wilkinson, J.

    2015-01-01

    Health Evidence Network Synthesis Report [Promoting better integration of health information systems: best practices and challenges K Michelsen, H Brand, P Achterberg, J Wilkinson - 2015 ... Authors Kai Michelsen Department of International Health, Maastricht University Maastricht,

  4. Kollaaž ja kontekst. Robert Rumase liiklusmärgid Tallinnas / Hanno Soans

    Index Scriptorium Estoniae

    Soans, Hanno, 1974-

    2004-01-01

    Sekkuv kunst. Poola kunstniku Robert Rumase (1966) rahvusvahelisest kunstiprojektist "Linnamanöövrid", Kai Kaljo videost "One way to see America", Krzysztof Wodicko "Kodutute projektsioonist" ja New York City Unioni väljaku ümberkorraldamisest

  5. 76 FR 13944 - Approval and Promulgation of Air Quality Implementation Plans; State of California; Regional Haze...

    Science.gov (United States)

    2011-03-15

    ... Wilderness; 14. Emigrant Wilderness; 15. Hoover Wilderness; 16. Yosemite National Park; 17. Ansel Adams... monitor) Ansel Adams WA, Kaiser WA, John 15.5 14.9 13.6 7.1 2200 Muir WA (KAIS monitor)......... Sequoia...

  6. Inglased kavatsevad Ida-Virumaale investeerida / Irina Tokareva

    Index Scriptorium Estoniae

    Tokareva, Irina

    2004-01-01

    Ilmunud ka: Severnoje Poberezhje, 22. okt. 2004, lk. 4. Suurbritannia saatkonna esimehe aset. William Elliott ning tööstus- ja investeeringute jaoskonna assistent Kai Tomasberg viibisid Ida-Virumaal, kus nad veendusid regiooni soodsates investeerimistingimustes

  7. Põlvas tuli esitusele Andre Laine 29 tantsu / Mati Määrits

    Index Scriptorium Estoniae

    Määrits, Mati, 1958-

    2008-01-01

    Põlva Kultuuri- ja Huvikeskuses sai näha Põlvamaa Koolitantsu maakondlikku eelvooru. 52st tantsust 29 tantsu autor on Andre Laine. Kommenteerib ka Tartu Ülikooli Viljandi Kultuuriakadeemia lavakunstide osakonna tantsukunsti õppejõud Kai Valtna

  8. Genetics Home Reference: asphyxiating thoracic dystrophy

    Science.gov (United States)

    ... JL, Bacchelli C, Tuysuz B, Hill J, Rix S, Pearson CG, Kai M, Hartley J, Johnson C, Irving ... Accessibility FOIA Viewers & Players U.S. Department of Health & Human Services National Institutes of Health National Library of ...

  9. Production and characterization of wine from mango fruit ( Mangifera ...

    African Journals Online (AJOL)

    Production and characterization of wine from mango fruit ( Mangifera indica ) varieties in Kenya. ... Six mature and unripe mango fruits were harvested three times from a farm in Katheka Kai Division, Machakos County ... HOW TO USE AJOL.

  10. Finnish Kalevala and Estonian Kalevipoeg / Jaan Puhvel

    Index Scriptorium Estoniae

    Puhvel, Jaan, 1932-

    2003-01-01

    Tõlgitud kogumikust: The world of the Kalevala : essays in celebration of the 150 year jubilee of the publication of the Finnish national epic / ed. Kai Laitinen. Los Angeles : UCLA Centre for the Study of Folklore & Mythology, 1987

  11. Darbo metu susenėjusių ir po suvirinimo termiškai apdorotų plieno 5 % Cr-0,5 % Mo virintinių jungčių struktūra ir savybės

    Directory of Open Access Journals (Sweden)

    Vigantas KUMŠLYTIS

    2012-06-01

    Full Text Available Straipsnyje nagrinėjamos suvirintos ir termiškai apdorotos chromo ir molibdeno (5 % Cr – 0,5 % Mo grupės plieno vamzdžių jungtys. Taip pat pateikiami ir palyginami ilgą laiką aukštoje temperatūroje eksploatuoto ir naujo chromo ir molibdeno plieno vamzdžio struktūra ir mechaninių savybių tyrimai. Eksploatuoto metalo tyrimams buvo panaudotas 530 °C temperatūroje 100 000 valandų dirbęs plieninis vamzdis. Tyrimais siekiama nustatyti 5 % Cr – 0,5% Mo grupės plienų suvirintųjų jungčių mechaninių savybių ir terminio apdorojimo parametrų tarpusavio priklausomybes. Atlikti suvirintų bandinių struktūros radiografiniai, mechaninių savybių, lūžių analizės ir mikrostruktūrų tyrimai. Nustatyta, kad chromo ir molibdeno plienų virintinių jungčių vidiniams įtempiams mažinti turi būti taikomas tik terminis apdorojimas. Kiti įtempių mažinimo metodai šiems plienams yra nepriimtini. Nustatyta, kad 5 % Cr – 0,5 % Mo plienų virintinių jungčių terminio apdorojimo temperatūros ir laiko parametro P reikšmė neturi viršyti 20,5. Viršijus šią reikšmę vyksta struktūros degradacijos procesas, karbidai pamažu transformuojasi į M23C6 karbidus, koaguliuoja ferito grūdelių ribose, sudaro karbidų kolonijas ar jungiasi į ilgus vientisus junginius. Smulkių, dispersiškų karbidų struktūroje nelieka. Taip pat mažėja jungties metalo takumo stipris ir smūginis tąsumas.DOI: http://dx.doi.org/10.5755/j01.ms.18.2.1911

  12. Kati Tolmoff: linn peabki oma sportlasi toetama / Maili Kangur

    Index Scriptorium Estoniae

    Kangur, Maili

    2009-01-01

    Tartlasest sulgpallur Kati Tolmoff sai Tartu Kultuurkapitali poolt olümpialootuse stipendiumi. Stipendiumi said ka Peeter Kümmel, Eveli Saue, Kristjan Kais, Rivo Vesik, Sirkka-Liisa Kivine, Tiidrek Nurme, Kaire Leibak, Künter Rothberg ja Maris Mägi

  13. Postkommunistlik kultuur ja kunst - kas müürid on lõhutud ? / Katrin Käärik ; foto: Katrin Käärik

    Index Scriptorium Estoniae

    Käärik, Katrin, 1950-

    1999-01-01

    Stockholmi Moodsa Kunsti Muuseumis avati 16. oktoobril 1999 rahvusvaheline näitus "Pärast müüri : kunst ja kultuur postkommunistlikus Euroopas", näitusest võtavad osa Jaan Toomik, Liina Siib, Kai Kaljo ja Inessa Josing

  14. Uus video, uus Euroopa / Kiwa

    Index Scriptorium Estoniae

    Kiwa, pseud., 1975-

    2006-01-01

    New Yorgi kunstikeskuses The Kitchen avatud endiste idablokimaade videokunstnike tööde näitusest. Eestlastest eksponeeritud Kiwa, Ene-Liis Semperi, Killu Sukmiti, Mari Laanemetsa, Tiia Johannsoni ja Kai Kaljo tööd. Kuraator Hamza Walker

  15. [Achievements and enlightenment of modern acupuncture therapy for stroke based on the neuroanatomy].

    Science.gov (United States)

    Chen, Li-Fang; Fang, Jian-Qiao; Chen, Lu-Ni; Wang, Chao

    2014-04-01

    Up to now, in the treatment of stroke patients by acupuncture therapy, three main representative achievements involving scalp acupuncture intervention, "Xing Nao Kai Qiao" (restoring consciousness and inducing resuscitation) acupuncture technique and nape acupuncture therapy have been got. Regarding their neurobiological mechanisms, the scalp acupuncture therapy is based on the functional localization of the cerebral cortex, "Xing Nao Kai Qiao" acupuncture therapy is closely related to nerve stem stimulation, and the nape acupuncture therapy is based on the nerve innervation of the regional neck-nape area in obtaining therapeutic effects. In fact, effects of these three acupuncture interventions are all closely associated with the modern neuroanatomy. In the treatment of post-stroke spastic paralysis, cognitive disorder and depression with acupuncture therapy, modern neuroanatomical knowledge should be one of the key theoretical basis and new therapeutic techniques should be explored and developed continuously.

  16. Aspects of vibrio parahaemolyticus(SAK) in fish preservation by irradiation 1. The presence of vibrio parahaemolyticus(SAK) in coastal areas of Sumatra and Java

    International Nuclear Information System (INIS)

    Suhadi, F.

    1984-01-01

    A study was carried out on the presence of vibrio parahaemolyticus in samples of sediment and seafoods originating from the eastern coast of Sumatra and the north coastal areas of Java. In a total of 2.434 samples of sediment and seafoods, 79 (3,3%) were found to contain vibrio parahaemolyticus. Among the 467 sediment samples, 1.650 fish, 133 shellfish, 123 shrimps, and 61 crab samples, 22 (4.7%), 41 (2.5%), 12 (9.0%), 2 (1,6%) and 2 (3.3%) were positive for vibrio parahaemolyticus, respectively. Based on the sampling areas, the high incidence of vibrio parahaemolyticus was found in samples collected from Riau (5.4%), while the samples from East Java was only about 0.4%. The contamination level of vibrio parahaemolyticus in samples collected from coastal areas of Sumatra and Java is relatively lower compared with the data obtained from some other coastal areas in the United States and Japan. (author)

  17. Klaasikunstnikud puhuvad ja valavad klaasi taas Haapsalus / Maris Sander

    Index Scriptorium Estoniae

    Sander, Maris

    2004-01-01

    Haapsalu 2. klaasipäevad "Maritima" (lad. keeles mereäärne) Evald Okase majamuuseumis. Osa võtavad kunstnikud Eestist, Koreast, Jaapanist ja Kanadast. Korraldaja Kai Koppel. Kommentaar Kati Kerstna. Valminud tööd pannakse näitusele

  18. [Eesti ajalugu III: Vene-Liivimaa sõjast Põhjasõjani] / Kalle Kroon

    Index Scriptorium Estoniae

    Kroon, Kalle, 1966-

    2014-01-01

    Arvustus. Enn Küng, Margus Laidre, Ivar Leimus, Aivar Põldvee, Anti Selart, Marten Sepepl, Kai Tafenau, Ülle Tarkiainen, Enn Tarvel. Eesti ajalugu III: Vene-Liivimaa sõjast Põhjasõjani. Tartu: Tartu Ülikooli Ajaloo ja Arheoloogia Instituut, 2013

  19. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Fang Dong1 Jiang Chenning1 Zhu Ting1 Yang Jinming1. Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering, Yancheng Teachers University, 50 Kai Fang Da Dao, Yancheng 224002, Jiangsu, P. R. China ...

  20. Ruumikujundused eelmisel aastal / Tuuli Org

    Index Scriptorium Estoniae

    Org, Tuuli

    2007-01-01

    Kokkuvõtted Kuressaare linna 2006. aasta ilusamatest ruumikujundustest: Ereki kontorihoone Pihtla tee 28 (Vello Liiv), kohvik Classic Lossi 9 (Kai Laanmets, Liina Saabas), Kuressaare gümnaasium Nooruse 1 (Vello Liiv), Vinoteek Lossi 4 (Ülle Kiirend, Anne Olop)

  1. Põhjalik koguteos Rootsi võidust / Kaarel Vanamölder

    Index Scriptorium Estoniae

    Vanamölder, Kaarel, 1981-

    2015-01-01

    Arvustus: Enn Küng, Margus Laidre, Ivar Leimus, Aivar Põldvee, Anti Selart, Marten Seppel, Kai Tafenau, Ülle Tarkiainen, Enn Tarvel. Eesti ajalugu III: Vene-Liivimaa sõjast Põhjasõjani. Tartu : Tartu Ülikooli Ajaloo ja arheoloogia instituut, 2013

  2. Research Article Special Issue

    African Journals Online (AJOL)

    pc

    2017-08-08

    Aug 8, 2017 ... Tupolev — KAI Kazan, Russian Federation. Published online: .... D and is the direct and an inverse DOT matrix of the dimension. N. N × ,. I. D. D. = ..... Embedded Programmable Logic Family/ Altera Inc. Cop. 1998. [Electronic.

  3. Zavodõ jest, biodizelja - net / Viktor Filonenko

    Index Scriptorium Estoniae

    Filonenko, Viktor, 1949-

    2008-01-01

    Eestis on viimastel aastatel loodud mitu biodiislit tootvat ettevõtet, kuid Eestis puuduva nõudluse tõttu biodiislit siin ei müüda. Vt. samas: Taimsest toorainest valmistatakse kütust Paldiskis. Kommenteerivad Kai Realo, Indrek Kaju ja Sven Mark

  4. Sõrve suvelaager aitab hoida sidet esivanemate kodumaaga / Lembit Suur

    Index Scriptorium Estoniae

    Suur, Lembit

    2007-01-01

    1953. aastast tegutsenud Sõrve laagril on põlisosa Austraalia eestlaskonna noorte tegevuskavas, laagri juhtkond ja Sõrve Sõprade Komitee asutasid sellel aastal noorte juhtide ergutuseks Kai Rahneli nimelise juhtimisauhinna ja see määrati Ian Carterile ja Dorothy Queale´ile

  5. Rigturm de Viena

    Directory of Open Access Journals (Sweden)

    Boltenstern, Erich

    1959-05-01

    Full Text Available El nuevo edificio para el Servicio Municipal de Seguros de la ciudad de Viena se halla enclavado a orillas del Danubio, en la esquina de las dos calles principales de la capital de Austria, Schottenring y Kai.

  6. Kuidas Harjumaal vanasti elati? / Ell-Maaja Randküla

    Index Scriptorium Estoniae

    Randküla, Ell-Maaja, 1939-2016

    2006-01-01

    Harjumaa muuseumi (Keila, Linnuse 9) püsinäitus "Harju elu". Sisekujundus: Krista Lepland, Malle Jürgenson, Hedi Roots, OÜ Laika, Belka & Strelka. Ehitus: OÜ Alpimer Ehitus. Kai Kaljo maalitud põrandavaip. Ill.: plaan, 22 värv. vaadet

  7. Iz Berlina v Tampere za neskolko tshasov? / Helga Balode

    Index Scriptorium Estoniae

    Balode, Helga

    2002-01-01

    Rail Baltica raudtee, mis hakkab reisi- ja kaubaronge teenindama marsruudil Tallinn-Varssavi, läheb maksma miljardeid kroone. Kommenteerivad Soome transpordi- ja kommunikatsiooniministeeriumi nõunik Kai-Peter Mattson, Läti sideministeeriumi raudteeosakonnajuhataja Janis Veidmanis ja Eesti raudteeameti peadirektor Oleg Epner

  8. Euroopa abiraha igatseb taotlejaid / Ain Alvela

    Index Scriptorium Estoniae

    Alvela, Ain, 1967-

    2008-01-01

    Aastatel 2007-2013 saab Eesti Euroopa Liidult toetusi 78 miljardit krooni, millele toetudes on võimalik rasked ajad üle elada. Vt. samas: Tuhahoidlast asula jäätmepunktini; Suurima toetuse saab keskkond. Kommenteerivad Antti Tooming ja Kai Niels Willadsen

  9. Videokunsti parimad stiilinäited Kumus

    Index Scriptorium Estoniae

    2010-01-01

    Kumu Kunstimuuseumis avatakse 28. oktoobril 2010 rahvusvaheline videokunsti näitus "Kõik saab korda". Osalevad Marina Abramović (Serbia/USA), Eija-Liisa Ahtila (Soome), Kai Kaljo, Mike Marshall (Inglismaa), Ene-Liis Semper, Santeri Tuori (Soome), Guido van der Werve (Holland)

  10. Maret Maripuu : HIV-haigete raviks jätkub raha ka järgmisel aastal / Maret Maripuu ; interv. Ille Grün-Ots

    Index Scriptorium Estoniae

    Maripuu, Maret, 1974-

    2008-01-01

    Sotsiaalministri Maret Maripuu sõnul leiab HIV-i vältimise vajalikkus üha rohkem kõlapinda kogu ühiskonnas ja poolele teele seisma jääda ei tohi. Kommenteerib Lääne-Tallinna Keskhaigla nakkuskeskuse juhataja Kai Zilmer

  11. Minge vaadake väärtfilme / Andres Laasik, Kaarel Kressa

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2008-01-01

    !". PÖFFi filme - Leedu mängufilm "Kui ma olin partisan" ("Kai as buvau partizanas"), režissöör Vytautas V. Lansbergis ja Mehhiko - Hispaania mängufilm "Tsoon" ("La Zona"), režissöör Rodrigo Pla

  12. What Does it Take to Travel Philosophically Light? A Response to Nielsen

    Directory of Open Access Journals (Sweden)

    Idil Boran

    2008-10-01

    Full Text Available In his reply to criticism raised against his reading of Rawls’s constructivist method in light of Rorty’s pragmatism, Kai Nielsen defends his position on the basis that it provides the tools for an external defence of liberalism. An external defence seeks to justify a liberal conception of justice in a way that will be acceptable not only to those who have already accepted the core substantive principles of liberal theory, but to those who reject these core principles. This paper assesses Nielsen’s proposal and shows that Rortian pragmatism is a limited way of achieving an external defence of liberal political and legal institutions. I propose to develop instead the idea of Kantian constructivism to this end. This discussion also brings to light broader questions about the idea of practical philosophy, and thus pays tribute to the works of John Rawls, Richard Rorty, and Kai Nielsen. Dans sa réplique à la critique faite de son interprétation de la méthode constructiviste de Rawls à la lumière du pragmatisme de Rorty, Kai Nielsen défend sa position en indiquant qu’elle offre des outils pour faire une défense externe du libéralisme. Une défence externe cherche à justifier une conception libérale de la justice d’une façon qui sera acceptable non seulement par ceux qui ont déjà accepté les principes importants de fond de la théorie libérale, mais par ceux qui rejettent ces principes de fond. Cet article évalue la proposition de Nielsen et démontre que le pragmatisme de Rorty est une façon limitée d’en arriver à une défense externe des institutions politiques et juridiques libérales. Je propose de développer plutôt l’idée de constructivisme kantien à cette fin. Cette discussion fait aussi ressortir des questions de plus grande envergure au sujet de l’idée de philosophie pratique et rend ainsi hommage aux oeuvres de John Rawls, Richard Rorty et Kai Nielsen.

  13. Kirju sadam : High Tech Center, Tammasaarenkatu, Helsingi = On the waterfront : High Tech Centre

    Index Scriptorium Estoniae

    2004-01-01

    Projekt koosneb viiest hoonest, millest neli asetsevad mere ääres Tammasaare tänaval ja viies Kaapeli väljakul. Projekteerija: arhitektibüroo Wartiainen, Evata Finland. Autor Kai Wartiainen. Valmis 2002. I korruse plaan, 4 välis ja 2 sisevaadet

  14. Commutators of Integral Operators with Variable Kernels on Hardy ...

    Indian Academy of Sciences (India)

    Home; Journals; Proceedings – Mathematical Sciences; Volume 115; Issue 4. Commutators of Integral Operators with Variable Kernels on Hardy Spaces. Pu Zhang Kai Zhao. Volume 115 Issue 4 November 2005 pp 399-410 ... Keywords. Singular and fractional integrals; variable kernel; commutator; Hardy space.

  15. CRED Gridded Bathymetry of Nihoa Island and transit to Kauai (100-026) in the Northwestern Hawaiian Islands

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — File 100-026b is a 60-m ASCII grid of depth data collected near Nihoa multibeam bathymetry data from a SeaBeam 210 sonar aboard the R/V Kai'imikai-O-Kanaloa...

  16. CRED Gridded Bathymetry of St. Rogatien and Brooks Banks (100-018) in the Northwestern Hawaiian Islands

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — File 100-018b is a 60-m ASCII grid of depth data collected near St. Rogatien multibeam bathymetry data from a SeaBeam 210 sonar aboard the R/V Kai'imikai-O-Kanaloa...

  17. Siim Nestor soovitab : Circulation. Sugar Daddy and Girls. Sopot. Diskoteek. Club Unlimited / Siim Nestor

    Index Scriptorium Estoniae

    Nestor, Siim, 1974-

    2002-01-01

    Tallinnas: 25. mai disko-suurüritusest Circulation. 24. mail klubis Wimbledon disko Sugar Daddy and Girls. 25. mail Von Krahlis erinevate muusikastiilide üritus Sopot. 24. mail Decolte's esineb trance-muusika Dj-kuningas Kai Tracid. 25. mail Diskoteek Tartu klubis Terminal.

  18. Keda küll huvitaks teerullid ja asfalt? = Who's interested in steamrollers and asphalt? / Epp Lankots

    Index Scriptorium Estoniae

    Lankots, Epp, 1976-

    2006-01-01

    Eesti Maanteemuuseum Varbusel. Sise- ja ekspositsioonikujundus: Laika, Belka & Strelka OÜ. Autorid Krista Lepland, Malle Jürgenson, kaasautor Tea Tammelaan. Maalingud: Kai Kaljo. Projekteerija: OÜ Restauraatorprojekt. Arhitekt Aarne Kann. Projekt 2001-2004, valmis 2005. Ill.: asendiplaan, 6 värv. sisevaadet, välisvaade

  19. THE DOUBLE CALL FOR JOY, “REJOICE AND BE GLAD” (MATT. 5 ...

    African Journals Online (AJOL)

    How can this call be applied to our present situation? 2. FUNCTION AND ... macarisms of Matthew 5:3-12 fall under this grammatical form. Characteristic of a ..... 5:13-16). The two imperatives caivrete kai;ajg allia`sqe are more than simple du-.

  20. Kes kaitseb röövelliku kiirlaenu eest? / Katrin Saks

    Index Scriptorium Estoniae

    Saks, Katrin, 1956-

    2008-01-01

    Kiirlaenudest ja nendega seonduvatest probleemidest Eestis, seaduseelnõust, mis suurendab SMS-laenu võtnute võimalusi kaitsta oma õigusi laenuandjate ees ning olukorra ohjeldamisest Rootsis ja Soomes. Ilmunud ka Pärnu Postimees 31. okt. 2008, lk. 11, pealkiri kujul: kaitse röövelliku kiirlaenu vastu ja tarbijakaitsepoliitika ; Lõunaleht 6. nov. 2008, lk. 4, pealkiri kujul: kes kaitseb röövelliku kiirlaenu eest ehk tarbijakaitsepoliitika lakmustest ; Vali Uudised 7. nov. 2008, lk. 2 ; Harju Ekspress 7. nov. 2008, lk. 8, pealkiri kujul: kes kaitseb röövelliku kiirlaenu vastu ehk tarbijakaitsepoliitika lakmustest ; Türi Rahvaleht 14. nov. 2008, lk. 4 ; Virumaa Teataja 14. nov. 2008, lk. 11, pealkiri kujul: kiirlaenud on test tarbijakaitsepoliitikale ; Kuulutaja 14. nov. 2008, lk. 4, pealkiri kujul: kes kaitseb kiirlaenu vastu ; Vooremaa 18. nov. 2008, lk. 2 ; Sõnumitooja 26. nov. 2008, lk. 2 ; Koit : Tarbijaleht 27. nov. 2008, lk. 10

  1. Creative style, personality, and artistic endeavor.

    Science.gov (United States)

    Gelade, Garry A

    2002-08-01

    Research has shown that creative style, as measured by the Kirton Adaption-Innovation Inventory (KAI; M. J. Kirton, 1976), is correlated with more than 30 different personality traits. In this article, the author demonstrates that many of these correlations can be understood within the framework of the Five-Factor Model of personality and shows that the predominant correlates of creative style are personality indicators in the domains of the factors Conscientiousness, Openness to Experience, and, to a lesser extent, Extraversion. These findings provide a basis for comparing the personality traits associated with creative style and occupational creativity. High scorers on the KAI (innovators) differ from both average and creative scientists but have personality characteristics similar to those of artists. This finding suggests that the artistic personality may be more common than is generally supposed and that common factors might underlie both artistic endeavor and creative style.

  2. Ciprofloxacin and Trimethoprim Cause Phage Induction and Virulence Modulation in Staphylococcus aureus

    Science.gov (United States)

    Goerke, Christiane; Köller, Johanna; Wolz, Christiane

    2006-01-01

    In Staphylococcus aureus strains of human origin, phages which integrate into the chromosomal gene coding for β-hemolysin (hlb) are widely distributed. Most of them encode accessory virulence determinants such as staphylokinase (sak) or enterotoxins. Here, we analyzed the effects of ciprofloxacin and trimethoprim on phage induction and expression of phage-encoded virulence factors by using isolates from patients with cystic fibrosis for which the induction of hlb-converting phages was demonstrated in vivo (C. Goerke, S. Matias y Papenberg, S. Dasbach, K. Dietz, R. Ziebach, B. C. Kahl, and C. Wolz, J. Infect. Dis. 189:724-734, 2004) as well as a φ13 lysogen of phage-cured strain 8325-4. Treatment of lysogens with subinhibitory concentrations of either antibiotic resulted in (i) delysogenization of strains resembling the isolates picked up after chronic lung infection and (ii) replication of phages in the bacterial host in a dose-dependent manner. Ciprofloxacin treatment resulted in enhanced recA transcription, indicating involvement of the SOS response in phage mobilization. Induction of φ13 was linked to elevated expression of the phage-encoded virulence gene sak, chiefly due to the activation of latent phage promoters. In summary, we could show the induction of hlb-converting phages and a subsequent virulence modulation of the host bacterium by ciprofloxacin and trimethoprim. PMID:16377683

  3. Desain Kapal 3-in-1 Penumpang-Barang-Container Rute Surabaya – Lombok

    Directory of Open Access Journals (Sweden)

    I Gede Hadi Saputra

    2017-01-01

    Full Text Available Dalam proses pembangunan ekonomi Indonesia, berbagai upaya telah dilakukan oleh pemerintah antara lain program Masterplan Percepatan dan Perluasan Pembangunan Ekonomi Indonesia (MP3EI dan juga Program Tol Laut. Program-program tersebut diambil oleh pemerintah agar terjadi pemerataan pembangunan ekonomi di setiap daerah demi meningkatkan kondisi ekonomi Indonesia. Dalam mengaplikasikan program tersebut, pemerintah membutuhkan sarana transportasi yang efisien dan salah satu alat transportasi tersebut adalah kapal 3-in-1. Kapal ini diharapkan mampu menjadi sarana transportasi dan juga sarana dalam pendistribusian barang dari Jawa ke Indonesia Timur sehingga mampu meningkatkan ekonomi di Indonesia bagian timur khususnya. Kapal 3-in-1 ini akan berangkat dari Pelabuhan Tanjung Perak, Surabaya menuju Pelabuhan Lembar, Lombok dengan kecepatan 17 knot. Dalam mendesain kapal dilakukan analisis teknis dan juga analisis ekonomis berupa menghitung biaya pembangunan kapal. Kapal yang didesain memiliki ukuran utama Length of Waterline (LWL: 130 meter, length of perpendicular (LPP: 125 meter, Breadth (B: 22 meter, Height (H: 11.7 meter, dan Draft (T: 6.6 meter. Dengan ukuran tersebut kapal ini mampu mengangkut penumpang sebanyak 488 orang, kontainer sebanyak 161 TEUs, dan semen sebanyak 3200 ton (di dalam bentuk sak di mana 1 sak semen sama dengan 40 kg. Dengan ukuran dan jumlah muatan tersebut seluruh regulasi dan ketentuan teknis telah terpenuhi. Besar biaya pembangunan kapal adalah sebesar Rp 77,302,629,498.00.

  4. Sustainable monitoring of roe deer in public hunting areas in the Spanish Pyrenes

    Energy Technology Data Exchange (ETDEWEB)

    Herrero, J.; Torres, R. T.; Prada, C.; Garcia-Serrano, A.; Gimenez-Anaya, A.; Fernandez, O.

    2013-07-01

    Aim of study: Monitoring trends in animal populations is essential for the development of appropriate wildlife management strategies. Area of study: The area is situated in the southern Pyrenees (Aragon), Spain. Material and methods: To measure the abundance, population trends, sex ratio, and mortality of roe deer populations, we analyzed data from i) driven hunts for wild boar (hunting seasons 1995/96-2009/10, n = 1,417, ii) itineraries, which were used to calculate the KAI and density using DS (2003-2010, n = 310 itineraries), iii) roe deer carcass recoveries (2006-2010, n = 100), and iv) data from the deer hunting quota fulfillment (2006-2010, n = 325 hunted animals. Main results: Based on DS, in 2010, the average density of roe deer populations was 2.3 km–2 (CV 17%). Based on the KAI and the battues, the estimated average annual rate of increase was 5.8% and 4.3%, respectively. Based on the KAI and the carcass recoveries, the estimates of the population sex ratio were 0.75 (n = 641) and 0.9 (n = 100) males per female, respectively. Carcass recoveries indicated that mortality was highest in late winter and early spring. The average body masses and sizes of males and females were within the ranges reported for other Iberian and European populations. Research highlights: Monitoring should be continued in the Aragon population of roe deer, although larger sample sizes are required to increase the accuracy of estimates and assessments of the impact of management actions. (Author)

  5. Eestlased graafikanäitustel / Benjamin Vasserman

    Index Scriptorium Estoniae

    Vasserman, Benjamin

    1999-01-01

    IV Kochi graafikatriennaalil Jaapanis 13. III-18. IV osales Eestist Benjamin Vasserman tööga "Vaheldus I". Peapreemia: Eduardo Roca Zalazar. XIV rahvusvahelisel graafikanäitusel "Premio Internationale Biella per I'Incisione" Itaalias 23. IV-23. V osalesid Eestist Peeter Allik, Reti Saks, Benjamin Vasserman. Näituse nimeline preemia: Seung Yeon Kim. 26. VIII avati Fredrikstadis 12. Norra rahvusvaheline graafikatriennaal. 5. nov. avatakse X Varna graafikabiennaal Bulgaarias, 15. XII ئ III Egiptuse graafikatriennaal Gizas. "International Print Triennial Cracow 2000" näitustest

  6. Perbedaan IFRS, U.S. GAAP, Dan PSAK: Investement Property

    OpenAIRE

    L.D., Nunik

    2010-01-01

    International accounting standards convergence which has been done through adopting IFRS completely by DSAK is IAS 40 Investment Property. Based on these adopting, there will be differentiation between IFRS, U.S. GAAP and PSAK. But for PSAK valid in January 1st 2008 (SAK in July 1st 2009), there are no differentiation with IFRS because PSAK adopts IFRS completely, but between IFRS, PSAK and U.S. GAAP have differentiation. This paper will only discuss about the differentiation between IFRS, U....

  7. Two Viewpoints on the Challenges of ICT in Education: Knowledge-Building Theory vs. a Pragmatist Conception of Learning in Social Action

    Science.gov (United States)

    Kivinen, Osmo; Piiroinen, Tero; Saikkonen, Loretta

    2016-01-01

    The paper contrasts two different approaches to the educational challenges of the ubiquitous, rapidly developing information and communication technologies (ICT). The first is the constructivist "knowledge building" theory spearheaded by Carl Bereiter and Marlene Scardamalia and recently further developed by Kai Hakkarainen and Sami…

  8. Ela ja sära - setu pitsist ekvaatorireisini / Andres Keil

    Index Scriptorium Estoniae

    Keil, Andres, 1974-

    2004-01-01

    Eesti Kultuurkapitali "Ela ja sära" stipendiumi laureaadid kirjanik Eeva Park, kunstnik Kai Kaljo, sporditeadlane Joe Noormets, näitleja Kersti Kreismann, pitsikunstnik Ulve Kangro, režissöör Marko Raat, disainer Tarmo Luisk ja helilooja Urmas Sisask oma loomingulistest plaanidest

  9. 77 FR 48520 - Granting of Request for Early Termination of the Waiting Period Under the Premerger Notification...

    Science.gov (United States)

    2012-08-14

    ... Berger SE; Westcon Holdings, Inc.; Bilfinger Berger SE. 20121084 G Sony Corporation; GaiKai Inc.; Sony..., 2012 Through July 31, 2012 07/02/2012 20121012 G Pinnacle West Capital Corporation; Edison International; Pinnacle West Capital Corporation. 20121022 G Vector Capital IV International. L.P.; Technicolor...

  10. Klaasis on pinget / Reet Varblane ; kommenteerinud Kati Kerstna, Kairi Orgusaar

    Index Scriptorium Estoniae

    Varblane, Reet, 1952-

    2009-01-01

    Klaasi kui (kunsti)materjali kasutamisest, mitmete erialade sümbioosist. Laura Mattioli Rossi, Rosa Barovier Mentasti ja Adriano Berengo kureeritud näitusest "Glass Stress" ("Klaasipinge") tänavusel Veneetsia biennaalil. Eesti klaasikunstist, Kai Koppeli eestvedamisel toimunud Haapsalu klaasipäevadest "Kasuta päeva"

  11. Täna kell 17.30 avatakse Tallinna Kunstihoones briti, eesti ja soome fotonäitus "Fantastiline realism"

    Index Scriptorium Estoniae

    2004-01-01

    Kuraator Eve Kiiler. Osalejad loetletud. Avamisel esineb Naeruorgesster. 28. II seminaril räägib Asko Mäkela soome fotokunstist, David Bate briti fotost, Mike Marshall, Denny Robson, Outi Liusvaara, Marja Pirilä, Kai Kaljo ja Piret Räni presenteerivad oma töid

  12. Kodu Rotterdami kaubasadamas / Ada Org

    Index Scriptorium Estoniae

    Org, Ada

    2005-01-01

    Vabakutselise kunstniku Sandy omapärasest kolmekorruselisest tellistest elamust aadressil kai number 2600. Enamus mööblist on korduvkasutuses, asjadele on leitud uus funktsioon, remonditööd on teinud Sandy ise. Kolmandal korrusel asuva vannitoa sisustus on uus. 13 värv. ill

  13. Department of Defense Atlas/Data Abstract for the United States and Selected Areas. Fiscal Year 1992

    Science.gov (United States)

    1993-01-01

    ZIMMERMIANN BASIL CORP JV 34,679 Operation/Ammunition Facilities 34,679 3. MORRISON KNUDSEN CORP 30,923 Facilities Operations Support Services 30,923 4...qFEMBACfl A A ABA NUERNBERG HEIDELBERG KAI-3ERSLAUTERN ASTUTTG ART Prepared Byt Washington Headquarters Servicee Directorate for Information Operations

  14. Internet seinakontaktist on tulevikumuusika / Kai Simson

    Index Scriptorium Estoniae

    Simson, Kai

    2004-01-01

    Näitusel Enerex 2004 tutvustas Schneider Electric Eesti AS esmakordselt Power Line Communicationi (PLC) ühendust, millega saab Internetti edastada ja jagada elektrivõrgu kaudu. Kommenteerivad Fortum Elekter AS-i Läänemaa regiooni võrgujuht Kaupo Kuurberg, Elion Ettevõtted AS-i meediasuhete juht Ain Parmas ja Eesti Energia Televõrgu AS-i juhataja Urmas Aiaste

  15. Märkmeid tantsuaastast 2003 / Kai Valtna

    Index Scriptorium Estoniae

    Valtna, Kai

    2004-01-01

    Ülevaade 2003. aasta tantsulavastustest Eesti lavadel. Pikemalt peatutakse lavastustel "Armastuse tango ehk Aegade lõpus" (lav. M. Murdmaa), "Outbound" (lav. M. Moles), "Mart on stage" (lav. M. Kangro), "Luikede järv" (lav. P. Jalakas ja S. Pepeljajev)

  16. Maksureformist saab valitsuse kirstunael / Kai Kalamees

    Index Scriptorium Estoniae

    Kalamees, Kai

    2005-01-01

    2006. aasta eelarve kokkupanemine ja eelarvestrateegia kinnitamine aastateks 2006-2009 võib aprillis-mais koalitsioonipartnerid taas konfliktini viia, kuna kahe järgneva aasta vältel ei ole võimalik samaaegselt langetada tulumaksu 20 protsendini ja täita koalitsioonileppe lubadusi. Lisad: Reformi juhatuses sisepinged; Maksureform

  17. Mis jääb kunstist lõpuks sõelale? / Tanel Veenre

    Index Scriptorium Estoniae

    Veenre, Tanel, 1977-

    2011-01-01

    15. Tallinna graafikatriennaalist "Armastuse, mitte raha pärast" Kumu Kunstimuuseumis. Triennaali kuraatorid: Simon Rees, Eve Kask, Eha Komissarov, kujundajad: Neeme Külm, Ralf Lõoke. Óskar Muñoze (Colombia), Ellie Daviesi (Suurbritannia), Andrew Raftery (USA), Kai Kuusingu ja Anu Kalmu töödest

  18. Klaas ja mõis / Maie-Ann Raun

    Index Scriptorium Estoniae

    Raun, Maie-Ann, 1938-

    2007-01-01

    Klaasikunstinäitus "Ringkäik" Albu mõisas, kuraatorid Virve Kiil, Kati Kerstna, Kairi Orgusaar. Eksponeeritakse Tiina Sarapu, Mare Saare, Eeva Käsperi, Kai Kiudsoo-Värvi, Pilvi Ojamaa, Merle Bukoveci, Kalli Seina, Viivi-Ann Keerdo, Liisi Junolaineni, Kristiina Uslari, Ivo Lille töid

  19. Tartu Ülikool raamatukogus / Tiina Tammet

    Index Scriptorium Estoniae

    Tammet, Tiina, 1971-

    2005-01-01

    Kuni 13 II näitus "R.A.I.S.K." (Radikaalne Agiteeriv Intrigeeriv Sotsiaalne Kunst). Krutskilist ökokunsti teevad Infotankistid, Puhas Rõõm, Piret Räni, Maris Suits, Katrin Tees, Anu Vahtra, Mart Viljus, Ivika Kivi & Sulo Kallas, Taavi Suits, Kai Herkel ja Henry van Noordenburg

  20. Uma leitura intertextual da poesia de Alberto Caeiro à luz da sabedoria zen-budista

    Directory of Open Access Journals (Sweden)

    Márcia Munir Miguel Feitosa

    2011-10-01

    Full Text Available Análise da poesia de Alberto Caeiro, heterônimo de Fernando Pessoa, à luz da filosofia zen-budista, tanto no que concerne ao culto da natureza, como no que diz respeito à questão do eu, inerente ao poeta português e à filosofia Zen. O estudo ainda inclui o levantamento das possíveis afinidades formais e estilísticas entre a poesia japonesa, representada pelos hai-kais, e a poesia sensacionalista de Caeiro.Análisis de la poesia de Alberto Caeiro, heterónimo de Fernando Pessoa a la luz de la filosofía zen-budista, tanto que concierne al culto de la naturaleza, como que dice respecto a la cuestión del yo, inherente al poeta portugués y a la filosofía zen. El estúdio aún incluye las posibles afinidades formales y estilísticas entre la poesia japonesa, representada por los hai-kais, y la poesia sensacionista de Caeiro.

  1. Hard X-ray photoemission spectroscopy

    International Nuclear Information System (INIS)

    Kobayashi, Keisuke

    2009-01-01

    Except in the very early stage of the development of X-ray photoemission spectroscopy (XPS) by Kai Siegbahn and his coworkers, the excitation sources for XPS studies have predominantly been the Al Kα and Mg Kα emission lines. The advent of synchrotron radiation sources opened up the possibility of tuning the excitation photon energy with much higher throughputs for photoemission spectroscopy, however the excitation energy range was limited to the vacuum ultra violet and soft X-ray regions. Over the past 5-6 years, bulk-sensitive hard X-ray photoemission spectroscopy using high-brilliance high-flux X-rays from third generation synchrotron radiation facilities has been developed. This article reviews the history of HXPES covering the period from Kai Siegbahn and his coworkers' pioneering works to the present, and describes the fundamental aspects, instrumentation, applications to solid state physics, applied physics, materials science, and industrial applications of HXPES. Finally, several challenging new developments which have been conducted at SPring-8 by collaborations among several groups are introduced.

  2. Akamai Internship Program

    Science.gov (United States)

    2015-04-17

    been  trained  through  the  ISEE   PDP     o 1  at  UH   Hilo   o 2  at   Hawaii  Community  College  (1  now...AFRL-OSR-VA-TR-2015-0094 AKAMAI INTERNSHIP PROGRAM Lisa Hunter UNIVERSITY OF HAWAII SYSTEMS Final Report 04/17/2015 DISTRIBUTION A: Distribution...NUMBER n/a 5f. WORK UNIT NUMBER n/a 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) University of Hawaii Systems 2530 Dole St. SAK D-200

  3. HÂRİCÎ LERİN “EL-EMRU Bİ’L-MA’RÛF VE’N-NEHYU ANİ’L-MÜNKER” ANLAYIŞI

    OpenAIRE

    Dalkıran, Sayın

    2010-01-01

    “El-Emru bi’l-ma’rûf ve’n-nehyu ani’l-münker / iyiliği emretmek kötülükten sakındırmak” prensibi İslam’da büyük bir öneme sahiptir. Bu bir görevdir ve her müslümanın yapması gereken bir emirdir. Ancak ilk dönemden günümüze kadar bu emrin yerine getirilmesi konusunda Müslüm...

  4. Tundmatu eesti disain / Ivar Sakk

    Index Scriptorium Estoniae

    Sakk, Ivar, 1962-

    2006-01-01

    Eesti disainist, selle teadvustamisest, disainiajaloo puudumisest. Eesti keraamika ajaloost on kirjutanud Leo Rohlin, klaasikunsti ajaloost Maie-Ann Raun, sisearhitektuuri ajaloost Krista Kodres. Kai Lobjakas on kirjutanud ülevaate "Märkmeid eesti disainist". Saksa disaineri Serge Rompza ja ameerika disainiteoreetiku Victor Margolini arvamusest näituse "Ajast ees" kohta

  5. Admiral Pitka kantakse maha

    Index Scriptorium Estoniae

    2013-01-01

    Kaitsevägi on otsustanud arvata teenistusest välja Eesti mereväe lipulaeva Admiral Pitka, mis tehakse varustusest tühjaks ja tagastatakse Taani kuningriigile. Miinitõrjeoperatsiooni või õppuse juhtimiseks mõeldud 74 meetri pikkune fregatt on seisnud rahapuudusel kai ääres 2008. aastast

  6. NREL Research Pushes Perovskites Closer to Market | News | NREL

    Science.gov (United States)

    even get close-to the above-20% efficiencies dominated by silicon solar panels. NREL researcher Kai Zhu ; Perovskites have a couple of major benefits over silicon solar panels. The silicon technology requires a high as excellent semiconductors. This means perovskite panels are more flexible than rigid silicon panels

  7. Modelling the autocovariance of the power spectrum of a solar-type oscillator

    DEFF Research Database (Denmark)

    Campante , T.L.; Karoff, Christoffer

    2010-01-01

    tool in the analysis of the more than 1000 solar-type stars expected to be observed as part of the Kepler Asteroseismic Investigation (KAI). We apply the aforementioned procedure to simulations of the Sun. Assuming different apparent magnitudes, we address the issues of how accurately and how precisely...

  8. Patterns of Cenozoic sediment flux from western Scandinavia

    DEFF Research Database (Denmark)

    Gołędowski, Bartosz; Nielsen, S.B.; Clausen, O.R.

    2012-01-01

    deposits in the North Sea, the post-mid-Miocene Molo and Kai Formations of the Norwegian Shelf, the southern North Sea delta system and large volumes of the Late Pliocene-Holocene Naust Formation. The sediment flux from Scandinavia during the Cenozoic is in general agreement with the detrital flux...

  9. The future existence of the believers according to 2 Thessalonians

    African Journals Online (AJOL)

    Test

    2010-08-14

    tan e[lqh/ ejndoxasqh nai ejn toi aJgivoi aujtou kai; qaumasqh nai ejn ... God and those who do not obey the gospel of our Lord Jesus'. (2 Th 1:8). ... John 3:2 and Revelation 22:4.25 It is a motif widely found in. Hebrew ...

  10. Kõik saab korda / Tamara Luuk

    Index Scriptorium Estoniae

    Luuk, Tamara, 1952-

    2010-01-01

    Rahvusvaheline videokunsti näitus "Kõik saab korda" Kumu Kunstimuuseumis 2. jaanuarini 2011. Kuraator Maria-Kristiina Soomre, kujundaja Berit Teeäär. Osalevad Marina Abramović (Serbia/USA), Eija-Liisa Ahtila (Soome), Kai Kaljo, Mike Marshall (Inglismaa), Ene-Liis Semper, Santeri Tuori (Soome), Guido van der Werve (Holland)

  11. Ida-Euroopa postkommunistliku kunsti näitus tulemas

    Index Scriptorium Estoniae

    1999-01-01

    Stockholmi uues Moderna Museeti hoones avab kuraatorite kollektiiv 16. okt. 1999 näituse "After the Wall", mis analüüsib Berliini müüri langemise järgset kunstiolukorda ja kultuurimuutusi Ida-Euroopas. Näitusele on valitud eestlastest Inessa Josing, Kai Kaljo, Liina Siib, Jaan Toomik

  12. ACUTE-TO-CHRONIC ESTIMATION (ACE V 2.0) WITH TIME-CONCENTRATION-EFFECT MODELS: USER MANUAL AND SOFTWARE

    Science.gov (United States)

    Ellersieck, Mark R., Amha Asfaw, Foster L. Mayer, Gary F. Krause, Kai Sun and Gunhee Lee. 2003. Acute-to-Chronic Estimation (ACE v2.0) with Time-Concentration-Effect Models: User Manual and Software. EPA/600/R-03/107. U.S. Environmental Protection Agency, National Health and Envi...

  13. Nest survival of piping plovers at a dynamic reservoir indicates an ecological trap for a threatened population

    Science.gov (United States)

    Anteau, Michael J.; Shaffer, Terry L.; Sherfy, Mark H.; Sovada, Marsha A.; Stucker, Jennifer H.; Wiltermuth, Mark T.

    2012-01-01

    In the past 60 years, reservoirs have reshaped riverine ecosystems and transformed breeding habitats used by the threatened piping plover (Charadrius melodus; hereafter plover). Currently, 29% of the Northern Great Plains plover population nests at reservoirs that might function as ecological traps because reservoirs have more diverse habitat features and greater dynamics in water levels than habitats historically used by breeding plovers. We examined factors influencing daily survival rates (DSR) of 346 plover nests at Lake Sakakawea (SAK; reservoir) during 2006–2009 by evaluating multiple a priori models, and we used our best model to hindcast nest success of plovers during 1985–2009. Our observed and hindcast estimates of nest success were low compared to published estimates. Previous findings indicate that plovers prefer nest sites that are low relative to water level. We found that elevation of nests above the water level had a strong positive correlation with DSR because water levels of SAK typically increased throughout the nesting period. Habitat characteristics on the reservoir differ from those that shaped nest-site selection for plovers. Accordingly, extraordinary nest loss occurs there in many years, largely due to inundation of nests, and based on low fledging rates those losses were not compensated by potential changes in chick survival. Therefore, our example supports the concept of ecological traps in birds because it addresses quantitative assessments of habitat preference and productivity over 25 years (since species listing) and affects a large portion of the population.

  14. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    CHEN AI-HUA1 MENG SU-CI2 ZHOU KAI1 WANG CONG-CONG1 ZHAO WEI2 WANG AI-JIAN2 QIAN JUN2. School of Chemistry & Chemical Engineering, Yancheng Institute of Technology, Yancheng 224051, People's Republic of China; School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang ...

  15. Final Report: Multi-Scale Analysis of Deformation and Failure in Polycrystalline Titanium Alloys Under High Strain-Rates

    Science.gov (United States)

    2015-12-28

    element simulations of polycrystalline Tita - nium alloys. Jour. Mech. Phys. Solids, 59(10):2157–2176, 2011. 5. S. Ghosh and M. Anahid. Homogenized...2013) 111 – 124. [72] P. Shade, Private communication. [73] H. Ogi, S. Kai, H. Ledbetter, R. Tarumi, M. Hirao, K. Takashima, Tita - niums high-temperature

  16. Mäss põhjusega : kortermaja Silodamil Amsterdamis / Klaske Havik

    Index Scriptorium Estoniae

    Havik, Klaske, 1975-

    2002-01-01

    Büroo MVRDV suurim elamuprojekt. Arhitektid Winy Maas, Jacob van Rijs, Nathalie de Vries, kaasa töötasid Frans de Witte, Willem Timmer, Eline Strijkers, Bernd Felsinger, Duzan Koepel. Viis võistlustöö kaasautorit. Hoone paikneb kai tipus, on ehitatud vette postide peale. Ill.: 7 plaani, 11 vaadet

  17. No mixed feelings : The post-Lisbon Common Commercial Policy in Daiichi Sankyo and Commission v. Council (Conditional Access Convention)

    NARCIS (Netherlands)

    Larik, J.E.

    2015-01-01

    Double case note on the scope of the EU's Common Commercial Policy and the future of "mixed agreements" based on the two ECJ Grand Chamber Judgements Case C-414/11, Daiichi Sankyo Co. Ltd and Sanofi-Aventis Deutschland GmbH v. DEMO Anonimos Viomichaniki kai Emporiki Etairia Farmakon, Judgment of the

  18. Igavese armastuse sõdalane : mitte just klassika, aga ajaloo verstapost küll / Ilmar Raag

    Index Scriptorium Estoniae

    Raag, Ilmar, 1968-

    2006-01-01

    Soome ja Hiina mütoloogiat ühendavast fantaasiafilmist "Igavese armastuse sõdalane - Jade Warrior" (Soome, Hiina, Hollandi, Eesti ühistöö) : stsenarist Iiro Küttner, režissöör Antti-Jussi Annila, võitluskunstide koreograaf Yu Yan Kai, osades - Tommi Eronen, Zhang Jingchu, Markku Peltola, Elle Kull

  19. Fassaadikunstist ja teesklusest / Margit Tõnson

    Index Scriptorium Estoniae

    Tõnson, Margit, 1978-

    2006-01-01

    Soome ja Hiina mütoloogiat ühendav fantaasiafilm "Igavese armastuse sõdalane - Jade Warrior" (Soome, Hiina, Hollandi ja Eesti ühistöö) : stsenarist Iiro Küttner : režissöör Antti-Jussi Annila : võitluskunstide koreograaf Yu Yan Kai : osades Tommi Eronen, Zhang Jingchu, Markku Peltola

  20. Novõi utshebnõi god budjet Godom dizaina / Ksenia Repson

    Index Scriptorium Estoniae

    Repson, Ksenia

    2006-01-01

    Eesti Kunstiakadeemia disainihariduse 40. aastapäeva tähistava Disainiaasta üritusi: rahvusvaheline disainikonverents Connecting, näitus "40 aastat disaini" Tarbekunsti- ja Disainimuuseumis, disainikonkurss, rändnäitused, seminarid, Tallinna disainikaart (koostab Kai Lobjakas, joonistavad Indrek Sirkel ja Mikk Heinsoo). Projekti "Disainiaasta" juht on Ruth Helene Melioranski

  1. Co-expression of the C-terminal domain of Yersinia enterocolitica ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 40; Issue 1. Co-expression of the C-terminal domain of Yersinia enterocolitica invasin enhances the efficacy of classical swine-fever-vectored vaccine based on human adenovirus. Helin Li Pengbo Ning Zhi Lin Wulong Liang Kai Kang Lei He Yanming Zhang. Articles Volume ...

  2. Resurrecting past futures / Thomas Cubbin

    Index Scriptorium Estoniae

    Cubbin, Thomas, 1987-

    2011-01-01

    Näitused "Modernisation. Baltic Art, Design and Architecrure in the 1960s-1970s" (kuraatorid Lolita Jablonskienė, Kai Lobjakas, Iliana Veinberga) ja "Our Metamorphic Futures: Design, technical aesthetics and experimental architecture in the Soviet Union 1960-1980" (kuraatorid Andres Kurg, Mari Laanemets) Vilniuse Rahvusgaleriis 9.12.2011-12.02.2012

  3. Uus Tartu Loodusmaja = The new Tartu Nature Building / Tiit Sild

    Index Scriptorium Estoniae

    Sild, Tiit, 1977-

    2010-01-01

    Tartu Loodusmaja avalikust arhitektuurivõistlusest, kvalifitseerimistingimustest, energiatõhususest ja žürii tööst. 1. preemia sai töö "Känd", autorid Diana Taalfeld, Kai Süda, Margit Valma, Martin Kinks (Urmas Lõokese AB / Karisma Arhitektid). Nimetatud 2. ja 3. koha saanud tööd, autorid

  4. Disease: H00056 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00056 Alzheimer's disease (AD) Alzheimer's disease (AD) is a chronic disorder tha...sak JM, Holtzman DM ... TITLE ... The role of apolipoprotein E in Alzheimer's disease. ... JOURNAL ... Neuron 63:2...87-303 (2009) DOI:10.1016/j.neuron.2009.06.026 ... PMID:18802446 ... AUTHORS ... Bertram L, Tanzi RE ... TITLE ... Thirty years of Alzheimer...Cacabelos R ... TITLE ... Pharmacogenomics in Alzheimer's disease. ... JOURNAL ... Methods Mol Biol 448:213-357 (2...008) DOI:10.1007/978-1-59745-205-2_10 ... PMID:17082447 ... AUTHORS ... Goedert M, Spillantini MG ... TITLE ... A century of Alzheimer

  5. Characterization of oil and gas reservoir heterogeneity. Annual report, November 1, 1990--October 31, 1991

    Energy Technology Data Exchange (ETDEWEB)

    1991-12-31

    The objective of the cooperative research program is to characterize Alaskan reservoirs in terms of their reserves, physical and chemical properties, geologic configuration and structure, and the development potential. The tasks completed during this period include: (1) geologic reservoir description of Endicott Field; (2) petrographic characterization of core samples taken from selected stratigraphic horizons of the West Sak and Ugnu (Brookian) wells; (3) development of a polydispersed thermodynamic model for predicting asphaltene equilibria and asphaltene precipitation from crude oil-solvent mixtures, and (4) preliminary geologic description of the Milne Point Unit.

  6. Characterization of oil and gas reservoir heterogeneity

    Energy Technology Data Exchange (ETDEWEB)

    1991-01-01

    The objective of the cooperative research program is to characterize Alaskan reservoirs in terms of their reserves, physical and chemical properties, geologic configuration and structure, and the development potential. The tasks completed during this period include: (1) geologic reservoir description of Endicott Field; (2) petrographic characterization of core samples taken from selected stratigraphic horizons of the West Sak and Ugnu (Brookian) wells; (3) development of a polydispersed thermodynamic model for predicting asphaltene equilibria and asphaltene precipitation from crude oil-solvent mixtures, and (4) preliminary geologic description of the Milne Point Unit.

  7. Necip Fazıl Kısakürek’in “Kaldırımlar” Şiiri Üzerine Dil Bilimsel Bir Çözümleme A Linguistic Analysis On Necip Fazıl Kısakurek’s Poem Called As ‘Kaldırımlar’

    Directory of Open Access Journals (Sweden)

    Yusuf TEPELİ

    2013-03-01

    önüyle şiirin başarısında ve kalıcılığında büyük paya sahiptir. Şiir dilden ayrı düşünülemeyeceği için şiir eleştirisi de dilden bağımsız gerçekleştirilemez. Şiirin yansıttığı duyguları, okuyucuya yaşattığı atmosferi birtakım öznel değerlendirmelerle aktarmak yerine tamamen metnin kendi söz varlığına dayanan, bilimsel bir yöntemle açıklamak ihtiyacı bu çalışmanın yapılmasında etkili olmuştur. Bu çalışma için Necip Fazıl Kısakürek’in şiirinin tercih edilmesinde şairin sapmalar ve aktarmalarla özgün imgeler yaratması, ses ögelerinden bolca yararlanması, konuşulan dilin verdiği rahat söyleyişi yakalaması etkili olmuştur. Şair kişinin yoğun iç hesaplaşmalarının, ruh çalkantılarının yansımalarını dış dünyanın gerçekliğiyle aktardığı mistik şiirler kaleme almıştır. “Kaldırımlar” şiiri tüm bu nitelikleri içermesi bakımından bizlere ideal bir dil malzemesi sağlamaktadır.Bu çalışmada, Necip Fazıl Kısakürek’in Kaldırımlar adlı şiiri dilbilimsel bakışla çözümlenmeye çalışılmıştır. Bunun için Doğan Aksan'ın "Şiir Dili ve Türk Şiir Dili" adlı eseri temel alınarak, Aksan’ın değişik şiir örnekleri üzerinde gösterdiği şiir inceleme yöntemi bir Kaldırımlar şiiri üzerinde uygulanmıştır.İki bölümden oluşan çalışmanın ilk bölümünde kısaca sözcük türleri üzerinde durulmuş, ikinci bölümde ise metnin söz varlığını oluşturan sözcüklerin dil bilimsel/ anlam bilimsel/ gösterge bilimsel incelemesi yapılmış, bulgular tablolaştırılarak aktarılmıştır. Metinde geçen sözcükler tür, anlam yönü, ses ögeleri bakımından incelenmiş, bunların duygu değerleri, geçiş sıklıkları ve birbirleriyle ilişkileri tespit edilerek çözümlemeye gidilmiştir.

  8. African Journal of Traditional, Complementary and Alternative ...

    African Journals Online (AJOL)

    Li-Long Liu, Kai Xu, Lu-Mei Kang, Shu-Ping Jiang, Qing-Hua Wang, Lei Zhang, Shao-Gui Wan, Hong-Ping Chen, 113-121 ... Cytological effects of pulsed electromagnetic fields and static magnetic fields induced by a therapeutic device on in vivo exposed rats · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT

  9. Collaborative Research: Neutrinos and Nucleosynthesis in Hot and Dense Matter

    Energy Technology Data Exchange (ETDEWEB)

    Alford, Mark [Washington Univ., St. Louis, MO (United States)

    2015-05-31

    The Topical Collaboration funded one of Prof. Alford's graduate students, Jun (Sophia) Han, by providing 75% of her support. The work reported here was wholly or partly supported by the Topical Collaboration. Additional support, e.g. for postdoc Kai Schwenzer, came from Nuclear Theory grant #DE-FG02-05ER41375.

  10. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Co-expression of the C-terminal domain of Yersinia enterocolitica invasin enhances the efficacy of classical swine-fever-vectored vaccine based on human adenovirus · Helin Li Pengbo Ning Zhi Lin Wulong Liang Kai Kang Lei He Yanming Zhang · More Details Abstract Fulltext PDF. The use of adenovirus vector-based ...

  11. Twee aardbewings of een? Die assosiasie van literêre motiewe in ...

    African Journals Online (AJOL)

    Net soos in die Matteus-evangeiie self, is hier geen duidelike aanduiding van 'n on- derlinge verband tussen die aardbewing en die ander verskynsels wat vermeld word nie. Sintaktiese merkers ontbreek, want die passasie bevat bloot vier frases wat asindeties op mekaar volg, plus een frase wat met 'n neweskikkende Kai ...

  12. Anonimiteit en pseudonimiteit van Bybelse geskrifte

    African Journals Online (AJOL)

    (ou gar de) deur Teopompus geskryf was nie. Hy ontmasker ook die fiktiewe aard van die aanklagte en beswaddering (tas diabolas kai tas loidorias, hais kegreutai tines). 'n Ander voorbeeld van geidentifiseerde vervalsings is die traktate wat die neo-Pitagoreërs aan hulle leermeester toegeskryf het, eeue na sy dood (kyk ...

  13. Üllatav seiklusfantaasia Soomest / Alar Niineväli

    Index Scriptorium Estoniae

    Niineväli, Alar

    2006-01-01

    Soome ja Hiina mütoloogiat ühendav fantaasiafilm "Igavese armastuse sõdalane - Jade Warrior" (Soome, Hiina, Hollandi ja Eesti ühistöö) : režissöör Antti-Jussi Annila : võitluskunstide koreograaf Yu Yan Kai : osades Tommi Eronen, Zhang Jingchu, Elle Kull. Lisa "Soome film sai Hiinas hea lepingu

  14. The interpretation and translation of galatians 5:12 | Tolmie | Acta ...

    African Journals Online (AJOL)

    As is evident from commentaries on Galatians and from various English translations, scholars do not agree on the meaning, rhetorical labelling and translation of the wish expressed by Paul in Galatians 5:12 ( [Ofelon kai; ajpokovyontai oiJ ajnastatou` nte” uJma`”). In this article various interpretations of this verse are ...

  15. Browse Title Index

    African Journals Online (AJOL)

    Items 51 - 100 of 1309 ... Li-Long Liu, Kai Xu, Lu-Mei Kang, Shu-Ping Jiang, Qing-Hua Wang, ... CR Sewani-Rusike, JE Iputo, EJ Ndebia, M Gondwe, DR Kamadyaapa ... K-M Man, W-C Chen, H-M Wang, H-Y Chen, J-L Shen, L-D Chen, F-J Tsai, ...

  16. Reformierakond naudib ülisuurt toetust / Agnes Kuus

    Index Scriptorium Estoniae

    Kuus, Agnes

    2007-01-01

    Ilmunud ka: Postimees : na russkom jazõke, 15. mai 2007, lk. 3. Uuringufirma TSN Emor korraldatud küsitluse kohaselt oli Reformierakonna toetus pärast pronkssõduri sündmusi 46%. Diagramm: Toetus parlamendierakondadele. Kommenteerivad: Kadri Must, Marek Strandberg, Jaanus Marrandi, Margus Tsahkna, Eiki Nestor. Vt. samas: Kai Kalamees. Võimupartnerid usuvad endasse

  17. Georgi söögituba Kotli majas / Helju Koger

    Index Scriptorium Estoniae

    Koger, Helju, 1943-

    2006-01-01

    Georg Lurichi järgi nime saanud söögitoast arhitekt Alar Kotli vanaisale kuulunud hoones Väike-Maarjas. Enne renoveerimist koliti hoone teise kohta. Söögitoa kujunduse tegi Kai Tort, mööbli valmistasid kohalikud puusepad, plekist lambid - Ilmar Aasumets. Omanik Avo Part. 7 värv. ill

  18. Big and small women facing small culture / Reet Varblane

    Index Scriptorium Estoniae

    Varblane, Reet, 1952-

    1999-01-01

    Feministlik kunst Eestis alates 1994. aastast. Näitustest EST. FEM, Kood-eks, Private Views. Videod. Fotoinstallatsioonid. Tuntumad kunstnikud: Mare Tralla, Ene-Liis Semper, Mari Laanemets, Eve Kiiler, Tiina Tammetalu, Kai Kaljo, Ly Lestberg, Liina Siib jt. Kunstnike rühmitused: F.F.F.F. Teemad: ema, väike naine, keha. 6 illustratsiooni

  19. Publikum svinger den retoriske taktstok

    DEFF Research Database (Denmark)

    Hansen, Jette Barnholdt

    2012-01-01

    Artiklen handler om revyvisen "Man binder os på mund og hånd" af Poul Henningensen med musik af Kai Normann Andersen, som oprindeligt var en del af den kulturradikale revykomedie Dyveke fra 1940, der bla. advokerede for seksuel frigørelse. Visen levede dog hurtigt sit eget liv uden for revyteatret...

  20. Uued muutused nõuavad enam selgitustööd / Katrin Saks

    Index Scriptorium Estoniae

    Saks, Katrin, 1956-

    2008-01-01

    Euroopa Liidu otsustest ja nende tähtsusest ning selgitamise vajadusest. Ilmunud ka Koit 22. jaan. 2008, lk. 6, pealkiri kujul: Muutused nõuavad poliitikutelt järjest enam selgitustööd, Meie Maa 22. jaan. 2008, lk. 2 ; Sakala 24. jaan. 2008, lk. 2 ; Valgamaalane 22. jaan. 2008, lk. 2 ; Virumaa Teataja 25. jaan. 2008, lk. 11 ; Lääne Elu 24. jaan. 2008, lk. 2 ; Pärnu Postimees 5. veeb. 2008, lk. 19

  1. Ohutusnõuded laste mänguasjadele muutuvad senisest karmimaks / Katrin Saks

    Index Scriptorium Estoniae

    Saks, Katrin, 1956-

    2008-01-01

    Euroopa Komisjoni avaldatud kauaoodatud mänguasjade ohtuse direktiivi eelnõust, mis reguleerib siin müüdavate mängukannide ohutusnõudeid. Ilmunud ka Meie Maa 23. okt. 2008, lk. 2, pealkiri kujul: nõuded laste mänguasjadele muutuvad karmimaks ; Põhjarannik 23. okt. 2008, lk. 2 ; Järva Teataja 25. okt. 2008, lk. 2, pealkiri kujul: lelude ohutusnõuded karmistuvad ; Kuulutaja 24. okt. 2008, lk. 4 ; Oma Saar 6. nov. 2008, lk. 5 ; Pärnu Postimees 7. nov. 2008, lk. 15 ; Valgamaalane 11. nov. 2008, lk. 2

  2. Seroprevalence of Infections with Dengue, Rift Valley Fever and Chikungunya Viruses in Kenya, 2007.

    Directory of Open Access Journals (Sweden)

    Caroline Ochieng

    Full Text Available Arthropod-borne viruses are a major constituent of emerging infectious diseases worldwide, but limited data are available on the prevalence, distribution, and risk factors for transmission in Kenya and East Africa. In this study, we used 1,091 HIV-negative blood specimens from the 2007 Kenya AIDS Indicator Survey (KAIS 2007 to test for the presence of IgG antibodies to dengue virus (DENV, chikungunya virus (CHIKV and Rift Valley fever virus (RVFV.The KAIS 2007 was a national population-based survey conducted by the Government of Kenya to provide comprehensive information needed to address the HIV/AIDS epidemic. Antibody testing for arboviruses was performed on stored blood specimens from KAIS 2007 through a two-step sandwich IgG ELISA using either commercially available kits or CDC-developed assays. Out of the 1,091 samples tested, 210 (19.2% were positive for IgG antibodies against at least one of the three arboviruses. DENV was the most common of the three viruses tested (12.5% positive, followed by RVFV and CHIKV (4.5% and 0.97%, respectively. For DENV and RVFV, the participant's province of residence was significantly associated (P≤.01 with seropositivity. Seroprevalence of DENV and RVFV increased with age, while there was no correlation between province of residence/age and seropositivity for CHIKV. Females had twelve times higher odds of exposure to CHIK as opposed to DENV and RVFV where both males and females had the same odds of exposure. Lack of education was significantly associated with a higher odds of previous infection with either DENV or RVFV (p <0.01. These data show that a number of people are at risk of arbovirus infections depending on their geographic location in Kenya and transmission of these pathogens is greater than previously appreciated. This poses a public health risk, especially for DENV.

  3. On a Quest for English

    Science.gov (United States)

    Waters, John K.

    2007-01-01

    This article reports the potential of online role-playing games to be a powerful tool for English as a second language (ESL) learning. When Professor Edd Schneider and game designer Kai Zheng suggested to attendees gathered in San Francisco last spring for the annual Game Developers Conference that massively multiplayer online role-playing games,…

  4. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Lei He. Articles written in Journal of Biosciences. Volume 39 Issue 1 March 2014 pp 63-74 Articles. Screening of cellular proteins that interact with the classical swine fever virus non-structural protein 5A by yeast two-hybrid analysis · Chengcheng Zhang Lei He Kai Kang Heng Chen ...

  5. Käsitöö teeb asjad paremaks / Karin Paulus

    Index Scriptorium Estoniae

    Paulus, Karin, 1975-

    2007-01-01

    Eesti ja inglise kunstnike ühisnäitusest "Minu maailm : uus subjektiivsus kaasaegses disainis" Eesti Tarbekunsti- ja Disainimuuseumis. Kuraatorid Emily Campell, Andree Cook, Kai Lobjakas. Eksponeeritakse Annike Laigo, Krista Leesi, Ülle Jehe, Kärt Ojavee töid. Inglismaad esindavad 7 kunstnikku, lähemalt Danny Browni ja Alison Willoughby töödest

  6. Eesti goes St. Etienne / Anna Roomet

    Index Scriptorium Estoniae

    Roomet, Anna

    2006-01-01

    Näitus Eesti Kunstiakadeemia tootedisaini osakonna magistrantide viimase kahe aasta projektide paremikust esindas Eestit disainibiennaalil St. Etiennis Prantsusmaal. Näituse panid üles Pent Talvet ja Pavel Sidorenko, näitusel osalejad: Anna-Maria Einla, Kätlin Kangur, Triin Kuusler, Andri Laidre, Veiko Liis, Liina-Kai Raivet, P. Sidorenko, P. Talvet, Ingela Viks, Triin Voss

  7. Exploration of the factor structure of the Kirton Adaption-Innovation Inventory using bootstrapping estimation.

    Science.gov (United States)

    Im, Subin; Min, Soonhong

    2013-04-01

    Exploratory factor analyses of the Kirton Adaption-Innovation Inventory (KAI), which serves to measure individual cognitive styles, generally indicate three factors: sufficiency of originality, efficiency, and rule/group conformity. In contrast, a 2005 study by Im and Hu using confirmatory factor analysis supported a four-factor structure, dividing the sufficiency of originality dimension into two subdimensions, idea generation and preference for change. This study extends Im and Hu's (2005) study of a derived version of the KAI by providing additional evidence of the four-factor structure. Specifically, the authors test the robustness of the parameter estimates to the violation of normality assumptions in the sample using bootstrap methods. A bias-corrected confidence interval bootstrapping procedure conducted among a sample of 356 participants--members of the Arkansas Household Research Panel, with middle SES and average age of 55.6 yr. (SD = 13.9)--showed that the four-factor model with two subdimensions of sufficiency of originality fits the data significantly better than the three-factor model in non-normality conditions.

  8. Readout of the UFFO Slewing Mirror Telescope to detect UV/optical photons from Gamma-Ray Bursts

    DEFF Research Database (Denmark)

    Kim, J. E.; Lim, H.; Nam, J. W.

    2013-01-01

    plane detector of Intensified Charge-Coupled Device (ICCD). The ICCD is sensitive to UV/optical photons of 200–650 nm in wavelength by using a UV-enhanced S20 photocathode and amplifies photoelectrons at a gain of 104–106 in double Micro-Channel Plates. These photons are read out by a Kodak KAI-0340...

  9. Homme kell 18 avatakse Villa Manini kaasaja kunsti keskuses...

    Index Scriptorium Estoniae

    2004-01-01

    Uue Euroopa foto- ja videokunstinäitus "Instant Europe", kus on väljas kümne hiljaaegu Euroopa Liitu astunud riigi - Küpros, Eesti, Läti, Leedu, Malta, Poola, Tšehhi, Slovakkia, Sloveenia, Ungari - kunstnike tööd. Kuraatorid Francesco Bonami ja Sarah Cosulich Canarutto. Eestit esindavad Jaan Toomik, Kai Kaljo, Ene-Liis Semper ja Liina Siib

  10. The Impact of an Assurance System on the Quality of Teaching and Learning--Using the Example of a University in Russia and One of the Universities in Germany

    Science.gov (United States)

    Szymenderski, Peggy; Yagudina, Liliya; Burenkova, Olga

    2015-01-01

    In this paper we consider the question of how quality assurance can have a real, positive impact on the quality of teaching and learning at universities, considering the realities of different systems--the system of control and the system of quality culture--in using the example of two universities: the KNITU-KAI in Russia and the TU Dresden in…

  11. Kofi Annan tahab kõnelusi Kosovo lõppstaatuse üle / Krister Paris

    Index Scriptorium Estoniae

    Paris, Krister, 1977-

    2005-01-01

    Kuni pole selge, milline staatus Kosovot tulevikus ootab, ei ole välisettevõtted huvitatud pikaajaliste investeeringute tegemisest selles piirkonnas. ÜRO eriesindaja Kai Eide raporti kohaselt on Kosovo teinud märkimisväärseid edusamme, kõnelused Kosovo tulevase staatuse üle võiksid alata juba sel aastal. Lisa: Läbirääkijate kolm tingimust

  12. Lin-Na and Yong-Xiu Afr J Tradit Complement Altern Med. (2014) 11 ...

    African Journals Online (AJOL)

    cadewumi

    Evaluation of anti-athletic fatigue activity of Schizandra chinensis aqueous extracts in mice. Afr J Pharm Pharmacol 3: 593-597. 4. Cao, Y., Hu, Y., Liu, P., Zhao, H.X., Zhou, X.J., and Wei, Y.M. (2012). Effects of a Chinese traditional formula Kai Xin San (KXS) on chronic fatigue syndrome mice induced by forced wheel running ...

  13. Eksistentsi krõbisev videolint / Janar Ala

    Index Scriptorium Estoniae

    Ala, Janar, 1979-

    2010-01-01

    Videokunsti näitus "Kõik saab korda" Kumu Kunstimuuseumis 2. jaanuarini 2011, kuraator Maria-Kristiina Soomre. Osalevad järgmised kunstnikud: Marina Abramović, Eija-Liisa Ahtila, Kai Kaljo, Mike Marshall, Ene-Liis Semper, Santeri Tuori, Guido van der Werve. Pikemalt serbia kunstniku Marina Abramović'i ja soome kunstniku Eija-Liisa Ahtila töödest

  14. Markus 16:1-8 in die konteks van 'n konstniksie van die Markaanse ...

    African Journals Online (AJOL)

    Aangesien ons in die geval van Markus nie oor 'n voorhande bron ter ... geringgeskat word wanneer ons ons die Markaanse gemeentekonteks probeer voorstel nie. Linnemann suggests ... that there must be some control exercised over ..... ëaxai náuxa)v ëaxaxoq Kai návxioi' 8i0kovo(; (Mark 9: 35), dit wil sê as mens.

  15. Nog steeds geslote eredienste? Deel2

    African Journals Online (AJOL)

    gronde berus nie. Verwysende na Johannes 17:21 sê hy dat die kerk altyd die een- heid moet soek en bewaar omdat ons almal lede van dieselfde liggaam is. ...... Munchen: Kai ser. Oosthuizen, A J G [1960] 1978b. Ons kerk, in Van Wyk 1978:31-34. Pannenberg, W 1958. Christlicher Glaube und menschliche Freiheit.

  16. Font Effects of Chinese Characters and Pseudo-Characters on the N400: Evidence for an Orthographic Processing View

    Science.gov (United States)

    Lv, Caixia; Wang, Quanhong

    2012-01-01

    Event-related brain potentials (ERPs) were recorded during a Chinese character decision task to examine whether N400 amplitude is modulated by stimulus font. Results revealed large negative-going ERPs in an N400 time window of 300-500 ms to stimuli presented in degraded Xing Kai Ti (XKT) font compared with more intact Song Ti (ST) font regardless…

  17. "Interstanding 3"

    Index Scriptorium Estoniae

    1999-01-01

    25. nov.-st Rotermanni soolalaos rahvusvaheline meediakunsti festival 'Interstanding 3' 'Beyond the Edge ئ Ülalpool piire'. Kuraator Ando Keskküla. Loetletud näitusel osalejad. Eestit esindavad Kai Kaljo, Kiwa, Marko Laimre, Mare Tralla. 26. ja 27. XI Rotermanni soolalaos toimuval konverentsil esinejad, ettekanded. Konverentsi kureerib Eric Kluitenberg Hollandist. Korraldajad: Eesti Kunstiakadeemia, Kaasaegse Kunsti Eesti Keskus.

  18. Uued professorid ja audoktorid

    Index Scriptorium Estoniae

    2009-01-01

    TÜ nõukogu valis rahvusvahelise õiguse professoriks Lauri Mälksoo, peremeditsiini professorik Ruth Kalda, spordipsühholoogia professoriks Lennart Raudsepa; audoktoriteks nimetati EELK peapiiskop Andres Taul, Groningeni ülikooli prof. Cornelius Theodor Hasselblatt, Tampere ülikooli emeriitprof. Kai Krohn, Hollandi Erasmuse Ülikooli prof. Frank G. Grosveld, Suurbritannia Sussexi ülikooli prof. George Nicholas von Tunzelmann

  19. Rapsist diislikütus : kallis ja tõrjutud / Heiki Raudla

    Index Scriptorium Estoniae

    Raudla, Heiki, 1975-

    2008-01-01

    Paldiski Lõunasadamas avatud Biodiesel Paldiski AS tehas loodab tulevikus täisvõimsuse juures toota 100 000 tonni biodiislikütust aastas, praegu eksporditakse kogu toodang peamiselt Lääne-Euroopasse ja Skandinaaviasse. Eesti tarbijale biodiislikütuse tootmist takistab peamiselt tooraine kõrge hind ning vähene nõudlus. Küsimusele vastavad Kai Realo ja Indrek Kaju

  20. Kohtusüsteemi reguleerimise probleeme / Kai Kullerkupp

    Index Scriptorium Estoniae

    Kullerkupp, Kai, 1975-

    1997-01-01

    Kohtute pädevuse piiritlemisest, "õigusemõistmisest" kohtunikuks mitteolevate ametnike poolt, kohtute haldusest, kohtunike õiguslikust seisundist ja teenistusjärelevalvest ning kohtutesisesest tööjaotusest

  1. Kaup kai kõrvalt maailma / Kadri Paas

    Index Scriptorium Estoniae

    Paas, Kadri, 1982-

    2008-01-01

    Ilmunud ka: Delovõje Vedomosti 23. juuli lk. 16. Tallinna Sadam investeerib Muuga ja Paldiski lõunasadama tööstusparkide arendamisse paarsada miljoni krooni. Lisa: Number; Panus pidevasse kaubavoogu; Üle 100 hektari tööstusparki

  2. Ines Karu tantsis end raamatusse / Kais Allkivi

    Index Scriptorium Estoniae

    Allkivi, Kais

    2008-01-01

    USAs ilmus raamat kõhutantsust "Kõhutants tähistamas püha naiselikkust" ("Belly Dance Celebrating the Sacred Feminine"). Raamatu autor on Martha Elena Burns. Eestlannadest on raamatus Ines Karu ja tema trupikaaslane Janne Mõistus. Lisaks fakte Ines Karust "Pühendunud tantsule"

  3. Res Publica soolo rikkus tavasid / Kai Kalamees

    Index Scriptorium Estoniae

    Kalamees, Kai

    2005-01-01

    Riigikogu aseesimeheks valiti Res Publica liige Taavi Veskimägi, nüüd on Riigikogu juhatuses kaks ühe partei liiget. Riigikogu aseesimeheks tagasi valitud Toomas Vareki hinnangul näitab see samm nii Res Publica kogenematust kui ka Eesti poliitilise kultuuri kehva taset

  4. Kai kurie Antano Baranausko verstos Biblijos (pseudoarchaizmai

    Directory of Open Access Journals (Sweden)

    Birutė Kabašinskaitė

    2011-12-01

    Full Text Available (PSEUDOARCHAISMEN IN ANTANAS BARANAUSKAS’ BIBELÜBERSETZUNGZusammenfassungIn seiner Bibelübersetzung (1901–1902; im weiteren BaB genannt verwendet Antanas Baranauskas aus stilistischen Gründen nicht nur die gängigen Archaismen der alten Texte, sondern auch künstliche morphologische Formen, welche den früheren Sprachzustand wiedergeben sollten, wie er nach den alten Texten, den Mundarten und den Erkenntnissen der historisch-vergleichenden Sprachwissenschaft sowie den Hypothesen des Autors rekonstruiert werden kann.Die in BaB vorkommenden durch das Fehlen der Partikel te- sowie die Endungen -ie, -y, -ai charakterisierten Formen des Kupitivs (geidžiamoji nuosaka sind in Anlehnung an ähnliche Formen des Kupitivs und Imperativs der Mundarten und alten Texte gebildet.Auf die Partikel te- hat Baranauskas wahrscheinlich deswegen verzichtet, weil er das ursprüngliche Paradigma des alten Optativs (der bei ihm als geistaikis bezeichnet wird wiederherstellen wollte.Die dreifachen Endungen der Kupitivformen hat der Autor nicht streng mit irgendwelchen konkreten Präsensstämmen verbunden, obwohl die Mundarten und insbesondere die alten Texte ein konsequenteres System aufweisen.Vom Gebrauch in den heutigen Mundarten und alten Texte unterscheidet sich die Vorgehensweise in BaB durch die häufige Verwendung der Formen mit -ai. Hier bekommen eine solche Endung nicht nur die ā-, sondern auch die ina- und sta-Stämme sowie die auf alten Nasalvokal ų + -va- auslautenden Infixpräsentien. Vorbild für die Formen auf -ai waren wahrscheinlich die in verschiedenen (besonders žemaitischen Mundarten vorkommenden Formen der 3. Person Indikativ Präsens auf -ai mit vorausgestellter Partikel, die in der Funktion des Kupitivs gebraucht werden können. Zur Bevorzugung der Formen auf -ai konnte die Angabe in Schleichers Grammatik veranlaßt haben, daß -ai der ursprüngliche (baltoslavische? Ausgang des Optativs gewesen sei.Ungewöhnlich und höchstwahrscheinlich künstlich sind in BaB die reflexiven Kupitivformen. Bei ihnen findet sich hier der Ausgang -ys(i (ob dieser auch bei ā-Stämmen Verwendung fand, ist schwer zu beurteilen – es waren keine entsprechenden Beispiele auffindbar. Möglicherweise ist dieser Ausgang verallgemeinert auf Grund von Beispielen wie te álkinis (neben te álkinies DP. ähnlich verhält es sich im Falle des Kupitivs der athematischen Verben. Wohl nach dem Muster altlitauischer Beispiele wie te saugti KN wird einigen athematischen Präsentien die Endung -y (gleichgesetzt mit dem Kupitivausgang der i-Stämme? zugewiesen; aber bei den Formen der 3. Person Präsens auf -st (<-sti wird das übliche -ie oder -ai verwendet, wohl weil sie mit den Formen der sta-Stämme in Verbindung gebracht wurden.Veranlaßt durch das Streben nach künstlicher Wiederherstellung des alten Kupitivparadigmas, kommt in BaB auch die eine oder andere unkorrekte, „analogische“ Form vor, die vom Infinitivstamm aus (twinie, Apsiwilkie oder mit Wechsel der Flexionsklasse (sutwirty; -i statt -ėja gebildet ist.Vorbild für auffällige Formen des Partizip Präsens auf -ti-nt- waren die von einem Teil des Žemaitischen verwendeten umgebildeten Paradigmen athematischer Verben; dort haben die Partizipien öfters einen Stamm auf -ta-nt- (aber neben miegtąs auch miegtįs. In Analogie zum Ausgang der 3. Person Präsens des i-Stämme verallgemeinert der Autor -ti-nt-: nach stovi (Kupitiv stovy – stovįs wurde eiti (eity – eitįs geschaffen.Bei einigen Formen des Dativ Singular der Substantiva verwendet BaB im Anschluß an Daukša und vielleicht nach den Nachbardialekten von Anykščiai die Endung -i der alten i- und Konsonantenstämme. Nach dem Vorbild Daukšas, Sirvydas’ und anderer alten Texte wird in einigen Fällen die pronominale Dativform mi gebraucht.Die Verwendung von -ys als Endung des Nominativ Singular des bestimmten Adjektivs zeigt wahrscheinlich, daß der Autor seinen früheren Plan aufgreift, die Endung mit dem älteren (und auch für einen Teil der Mundarten charakteristischen Ausgang -ys der ia-Stämme zu verbinden. Wie den Briefen zu entnehmen ist, entschloß er sich etwa Mitte 1882, die Nominativ-Singularendung der bestimmten Adjektiva und Partizipien (ebenso die des Superlativs der Adjektiva zum Ausgang -ias der a-Stämme in Beziehung zu setzen, welcher nach seiner Ansicht nur zu -is kontrahiert werden konnte. Beim übersetzen der Bibel kehrte er zum Teil wieder zu seiner in der ersten Hälfte des Jahres 1882 praktizierten Verfahrensweise zurück und verwendete bei den bestimmten Adjektiven die Endung -ys.

  5. Legendaarsed toolid Eesti Rahva Muuseumis / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2005-01-01

    Tartu Kõrgema Kunstikooli mööbliosakonna loodud ja ennistatud mööbli näitus "Mööbel. Uksed. Pööning. Vanad tehnikad ja uus elu" Eesti Rahva Muuseumi näitusemajas. Näha saab Kölni messil auhinnatud Priit Verlini kujundatud istet "Allegro", esemeid Leonhard Vene ajaloolise mööbli kogust, Viini mööblikujundaja Koloman Moseri "dr Z-le" loodud ja Tartu ekspertide poolt restaureeritud tooli

  6. Complex function theory

    CERN Document Server

    Sarason, Donald

    2007-01-01

    Complex Function Theory is a concise and rigorous introduction to the theory of functions of a complex variable. Written in a classical style, it is in the spirit of the books by Ahlfors and by Saks and Zygmund. Being designed for a one-semester course, it is much shorter than many of the standard texts. Sarason covers the basic material through Cauchy's theorem and applications, plus the Riemann mapping theorem. It is suitable for either an introductory graduate course or an undergraduate course for students with adequate preparation. The first edition was published with the title Notes on Co

  7. Substituted dihydronaphthalenes as efflux pump inhibitors of Staphylococcus aureus

    DEFF Research Database (Denmark)

    Thota, Niranjan; Reddy, Mallepally V; Kumar, Ashwani

    2010-01-01

    A new series of 3-(substituted-3,4-dihydronaphthyl)-2-propenoic acid amides has been prepared through convergent synthetic strategies and tested in combination with ciprofloxacin against NorA overexpressing Staphylococcus aureus 1199B as test strain for potentiating of the drug activity. Out of 24...... compounds evaluated, 12 compounds potentiated the activity of ciprofloxacin and resulted in 2-16 fold reduction in the MIC (4-0.5 microg/mL) of the drug. The failure of these efflux pump inhibitors (EPIs) to potentiate the activity of ciprofloxacin when tested against NorA knock out S. aureus SA-K1758...

  8. Regulated functions and integrability

    Directory of Open Access Journals (Sweden)

    Ján Gunčaga

    2009-04-01

    Full Text Available Properties of functions defined on a bounded closed interval, weaker than continuity, have been considered by many mathematicians. Functions having both sides limits at each point are called regulated and were considered by J. Dieudonné [2], D. Fraňková [3] and others (see for example S. Banach [1], S. Saks [8]. The main class of functions we deal with consists of piece-wise constant ones. These functions play a fundamental role in the integration theory which had been developed by Igor Kluvanek (see Š. Tkacik [9]. We present an outline of this theory.

  9. Baltimaade klaasikunstil on arenguruumi, vajaka jääb võimalustest / Mare Saare

    Index Scriptorium Estoniae

    Saare, Mare, 1955-

    2008-01-01

    Rahvusvaheline klaasinäitus "Vitrum Balticum IV" ("Balti klaas IV") Kaunases kuni 7. XII. Esindatud on Eesti (Kai Kiudsoo-Värv, Eeva Käsper, Ivo Lill, Kairi Orgusaar, Mare Saare, Maret Sarapu, Tiina Sarapu), Läti, Leedu ja Soome klaasikunstnikud. 14. XI rahvusvaheline seminar Läänemeremaade klaasikunsti arengukäigust 21. sajandil kunstiakadeemias. Näituse ja seminari kuraator kunstiteadlane Raimonda Kogelyte-Simanatiene

  10. Ida-Euroopa kunsti meganäitus Stockholmis

    Index Scriptorium Estoniae

    1999-01-01

    Stockholmi Moodsa Kunsti Muuseumis 16. X 1999-16. I 2000 Kesk- ja Ida-Euroopa kunsti näitus 'After the Wall'. Kuraatorid David Elliott, Bojana Pejic, Iris Müller-Westermann. Eestist osalevad Inessa Josing, Kai Kaljo, Liina Siib, Jaan Toomik. Näituse kataloogis on Jaan Kaplinski ja Heie Treieri artiklid, kataloogile tegid koostööd Johannes Saar, Raoul Kurvitz

  11. Ida-Euroopa kunstnikud koostöövalmis

    Index Scriptorium Estoniae

    2002-01-01

    21. II-31. III Tallinna Kunstihoones Viinis ja Budapestis tegutseva galeristi ja kuraatori Hans Knolli koostatud näitus "An artist who does not speak English is not an artist". Osalevad Lucehezar Boyadijev (Sofia), Aleksandr Brener, Barbara Schurz (Moskva, Viin), Rza El-Hassan (Budapest), Kai Kaljo, Roman Ondák (Bratislava), Mladen Stilinovic (Zagreb), Milica Tomic (Belgrad). Avamisel K. Kaljo performance

  12. "Jade Warrior" kupatab Soome sampo Hiina / Kätlin Kaldmaa

    Index Scriptorium Estoniae

    Kaldmaa, Kätlin, 1970-

    2006-01-01

    Soome ja Hiina mütoloogiat ühendav fantaasiafilm "Igavese armastuse sõdalane - Jade Warrior" (Soome, Hiina, Hollandi ja Eesti ühistöö) : stsenarist Iiro Küttner : režissöör Antti-Jussi Annila : võitluskunstide koreograaf Yu Yan Kai : osades Tommi Eronen, Zhang Jingchu, Markku Peltola. Lisatud Ave Randviiru, Elle Kulli ja Antti-Jussi Annila "Esimesed muljed"

  13. NCCR Chemical Biology: Interdisciplinary Research Excellence, Outreach, Education, and New Tools for Switzerland.

    Science.gov (United States)

    Sturzenegger, Susi; Johnsson, Kai; Riezman, Howard

    2011-01-01

    Funded by the Swiss National Science Foundation to promote cutting edge research as well as the advancement of young researchers and women, technology transfer, outreach and education, the NCCR (Swiss National Centre of Competence in Research) Chemical Biology is co-led by Howard Riezman, University of Geneva and Kai Johnsson, École Polytechnique Fédérale de Lausanne (EPFL).

  14. Product marketing for eco-power; Produktemarketing fuer Oekostrom

    Energy Technology Data Exchange (ETDEWEB)

    Huber, D. [Verband Schweizerischer Elektrizitaetswerke, Zuerich (Switzerland)

    1998-10-30

    The company NaturEnergie (natural energy), a subsidiary of the Energieversorger Kraftwerk Laufenburg AG (KWL) is located in Grenzach-Whylen (Germany) near Basel (Switzerland) has been selling power generated from sun and water since the 1st of October 1998. The company employes a cleverly designed, emotional marketing strategy in order to position the brand ``NaturEnergie`` as a label for ``green power`` on the market. Bulletin VSE talked to Dr. Kai-Hendrik Schlusche (40), co-founder and member of the board of NaturEnergie AG about marketing and pricing of ``green`` power and about relations with Switzerland.(orig.) [Deutsch] Im grenznahen Grenzach-Whylen bei Basel verkauft die Firma NaturEnergie, eine Tochtergesellschaft der Energieversorger Kraftwerk Laufenburg AG (KWL) und Kraftuebertragungswerke Rheinfelden AG (KWR), seit 1. Oktober 1998 Oekostrom aus Sonne und Wasser. Mit Hilfe einer ausgekluegelten emotionellen Marketingstrategie will das junge Unternehmen die Marke `NaturEnergie` als Label fuer `gruenen Strom` im Markt positionieren. Bulletin VSE sprach mit Dr. Kai-Hendrik Schlusche (40), seit Mai 1998 Gruendungsvorstand der NaturEnergie AG, ueber Marketing, Preisgestaltung von `gruenem Strom` und die Beziehungen zur Schweiz. (orig.)

  15. Selection indicates preference in diverse habitats: a ground-nesting bird (Charadrius melodus) using reservoir shoreline.

    Science.gov (United States)

    Anteau, Michael J; Sherfy, Mark H; Wiltermuth, Mark T

    2012-01-01

    Animals use proximate cues to select resources that maximize individual fitness. When animals have a diverse array of available habitats, those selected could give insights into true habitat preferences. Since the construction of the Garrison Dam on the Missouri River in North Dakota, Lake Sakakawea (SAK) has become an important breeding area for federally threatened piping plovers (Charadrius melodus; hereafter plovers). We used conditional logistic regression to examine nest-site selection at fine scales (1, 3, and 10 m) during summers 2006-2009 by comparing characteristics at 351 nests to those of 668 random sites within nesting territories. Plovers selected sites (1 m(2)) that were lower than unused random sites, increasing the risk of nest inundation. Plovers selected nest sites that were flat, had little silt, and at least 1 cobble; they also selected for 3-m radius nest areas that were relatively flat and devoid of vegetation and litter. Ninety percent of nests had nest sites (11% median), but against in the area 10-m from the nest, suggesting plovers select for patches or strips of gravel. Although elevation is rarely evaluated in studies of ground-nesting birds, our results underscore its importance in habitat-selection studies. Relative to where plovers historically nested, habitat at SAK has more diverse topography, substrate composition, vegetation communities, and greater water-level fluctuations. Accordingly, our results provide an example of how habitat-selection results can be interpreted as habitat preferences because they are not influenced by desired habitats being scarce or absent. Further, our results will be useful for directing habitat conservation for plovers and interpreting other habitat-selection studies.

  16. Lipids as organizers of cell membranes.

    Science.gov (United States)

    Kornmann, Benoît; Roux, Aurélien

    2012-08-01

    The 105th Boehringer Ingelheim Fonds International Titisee Conference 'Lipids as Organizers of Cell Membranes' took place in March 2012, in Germany. Kai Simons and Gisou Van der Goot gathered cell biologists and biophysicists to discuss the interplay between lipids and proteins in biological membranes, with an emphasis on how technological advances could help fill the gap in our understanding of the lipid part of the membrane.

  17. Australian Defence Force Requirements for a Group-feeding Ration Pack

    Science.gov (United States)

    2010-04-01

    Kai Si Ming 2 x 500g Chicken, pasta & veg 2 x 500g Frankfurters 2 x 185g Chicken curry 2 x 500g Sausages & spaghetti 2 x 500g Spaghetti & meatballs 2...Tomato & Onions Spaghetti & Meatballs Sweet Corn None Some All Very Bad Bad Neutral Good Very Good Q.12. go to Q.12. Q.7. On average, how many hours per

  18. Aksara Incung Kerinci Sebagai Sumber Ide Penciptaan Seni Kriya

    OpenAIRE

    Mubarat, Husni

    2015-01-01

    Aksara Incung Kerinci merupakan naskah kuno yang dipakai oleh suku Kerinci pada dahulunya sebagai wahana untuk menulis sastra, hukum adat, dan mantera- mantera yang ditulis pada kulit kayu, tanduk kerbau, bambu dan daun lontar. Aksara Incung digunakan sebagai sumber penciptaan karya. Penciptaan karya ini melalui tiga tahap, yaitu eksplorasi, perancangan, dan perwujudan melalui pencarian bentuk seni kriya yang baru, kreatif, dan inovatif, dengan tidak meninggalkan kaidah-kai...

  19. Sotsiaalselt pime ja poliitiliselt impotentne teater / Alvar Loog

    Index Scriptorium Estoniae

    Loog, Alvar

    2006-01-01

    Poliitilisest ja sotsiaalsest teatrist Eestis 2005. aasta lavastuste põhjal : Pip Upponi "Adolf" Tartu Püssirohukeldris, lavastaja Ervin Õunapuu; Merle Karusoo "Misjonärid" Rakvere Teatris; Alistair Beatoni "Õnnetunne" Ugalas, lavastaja Jaak Allik; Toomas Kalli " Viimane sent" Vana Baskini Teatris, lavastaja Eino Baskin; George Orwelli "Loomade farm" Tallinna Linnateatris, lavastaja Mart Koldits; Kai Henseli "Klammi sõda" VAT Teatris, lavastaja Aare Toikka

  20. Poeetilise utoopia meister Aino Bach

    Index Scriptorium Estoniae

    2003-01-01

    28. III-11. V Adamson-Ericu muuseumis graafik Aino Bachi loomingu ülevaatenäitus. Võrdluseks on eksponeeritud Eduard Wiiralti ja Kaarel Liimandi tööd. Näha võib Mark Soosaare filmi A. Bachist "Liblikapüüdja" (1978). Kuraator Anne Lõugas, kujundaja Virge Jõekalda. Kai Tuviku juhendamisel muuseumitunnid "Kuidas joonistada inimest?". 1. IV seminaril "Naiskunstnik ja tema aeg. Aino Bach" esinejad, ettekanded

  1. Analisis Fitur M-Ticketing PT. Kereta Api Indonesia sebagai Bagian dari Customer Relation Management (CRM)

    OpenAIRE

    Hijrih, Fatchul; Prasetyo, Taufan Harry

    2015-01-01

    Sebagai Perusahaan jasa tranportasi darat yaitu kereta api, PT. Kereta Api Indonesia perlu memperhatikan aspek pelayanan terhadap pelanggan dengan memperhatikan fitur-fitur Customer Relation Management dalam membuat dalam membuat aplikasi-aplikasi yang berhubungan langsung dengan pelanggan, salah satunya m-ticketing. Kemunculan m-ticketing KAI saat ini digunakan sebagai alat penjualan tiket saja. Hal ini dapat terlihat dari menu atau fitur-fitur yang disematkan kedalam aplikasi tersebut. Adan...

  2. Lego clocks: building a clock from parts.

    Science.gov (United States)

    Brunner, Michael; Simons, Mirre J P; Merrow, Martha

    2008-06-01

    A new finding opens up speculation that the molecular mechanism of circadian clocks in Synechococcus elongatus is composed of multiple oscillator systems (Kitayama and colleagues, this issue, pp. 1513-1521), as has been described in many eukaryotic clock model systems. However, an alternative intepretation is that the pacemaker mechanism-as previously suggested-lies primarily in the rate of ATP hydrolysis by the clock protein KaiC.

  3. Tuhkatriinust printsessiks / Heie Treier

    Index Scriptorium Estoniae

    Treier, Heie, 1963-

    1999-01-01

    Ida- ja Kesk-Euroopa 1990ndate kunsti näitus 'Pärast müüri' ('After the Wall') Stockholmis Moderna Museetis. Kureerinud David Elliott, Bojana Pejic, Iris Müller-Westermann. Seminarist. Eesti kunstnike Jaan Toomiku, Kai Kaljo, Liina Siibi, Inessa Josingu esinemisest. Kommenteerivad Moskva kuraator J. Bakstein, rootsi kunstikriitik C. Chambert, makedoonia kuraator S. Milevska, ajakirja NU toimetaja J.-P. Nilsson, New Yorgi kunstikriitik K. Levin

  4. Exponential Lower Bounds for the PPSZ k-SAT Algorithm

    DEFF Research Database (Denmark)

    Chen, Shiteng; Scheder, Dominik Alban; Talebanfard, Navid

    2013-01-01

    In 1998, Paturi, Pudl´ak, Saks, and Zane presented PPSZ, an elegant randomized algorithm for k-SAT. Fourteen years on, this algorithm is still the fastest known worst-case algorithm. They proved that its expected running time on k-CNF formulas with n variables is at most 2(1−k)n, where k 2 (1/k).......). So far, no exponential lower bounds at all have been known. In this paper, we construct hard instances for PPSZ. That is, we construct satisfiable k-CNF formulas over n variables on which the expected running time is at least 2(1−k)n, for k 2 O(log2 k/k)....

  5. Optimization of waste water discharge and waste water cleaning on the basis of measurements of the organic pollutant load; Optimierung von Abwasserableitung und Abwasserreinigung durch Messung der organischen Abwasserbelastung

    Energy Technology Data Exchange (ETDEWEB)

    Haeck, M. [Dr. Bruno Lange GmbH Berlin, Duesseldorf (Germany)

    1999-07-01

    The spectral absorption coefficient (SAC) is a sum parameter for describing the organic pollutant load of waste water. It is based on a purely physical measuring technique and can be monitored continuously and directly in the medium by means of the described UV process probe. From this arise numerous opportunities for optimizing waste water discharge and cleaning. (orig.) [German] Der spektrale Absorptionskoeffizient (SAK) ist ein Summenparameter zur Beschreibung der organischen Abwasserbelastung. Er basiert auf einem rein physikalischen Messverfahren und kann mit der hier vorgestellten UV-Prozess-Sonde kontinuierlich und direkt im Medium erfasst werden. Daraus ergeben sich zahlreiche Moeglichkeiten zur Optimierung von Abwasserableitung und -reinigung. (orig.)

  6. Disaini abil edukaks / Bo Englund ; interv. Kai Lobjakas

    Index Scriptorium Estoniae

    Englund, Bo

    2005-01-01

    Euroopa Disainiühenduste büroost (Bureau of European Design Association - BEDA), rahvuslikust disainipoliitikast, Rootsi-Eesti disainikonverentsist "Innovatsioon läbi disaini - disaini oma tulevik" Viinistu Kunstimuuseumis. Kommentaar Karin Pauluselt

  7. Hansapanga kunstisaal tutvustab Läti kunsti / Kai Vahe

    Index Scriptorium Estoniae

    Vahe, Kai

    2000-01-01

    2000. a. dets. lõpuni oli kunstisaalis avatud läti 5 kunstniku näitus "Distants" - Aija Zarina, Ieva Iltnere, Sarmite Malina, Anita Zabilevska ja Kristaps Gelzis. Väljendavad suhet ümbritsevasse iroonia kaudu

  8. Turule tuleb veel üks arvutipood / Kai Simson

    Index Scriptorium Estoniae

    Simson, Kai

    2004-01-01

    2004. a. detsembri alguses alustas tegevust jaekaubanduskett Enter IT-Market, mille eesmärk on pakkuda kõigis Eesti maakonnakeskustes kodukasutajatele suurimat valikut arvuti- ja digikaupu ühest kohast

  9. Kultuuriruum ja Natalie Mei prostitutsiooniteemalised joonistused / Kai Stahl

    Index Scriptorium Estoniae

    Stahl, Kai

    2011-01-01

    Analüüsitakse feministliku lugemise ja Juri Lotmani kultuurisemiootika abil kultuuri ja "mittekultuuri" vahelist piiriala, keskendudes viisidele, kuidas Natalie Mei erines oma joonistustega kunsti üldpildist - rikkudes traditsionaalset pildikoodi, ironiseerib Mei selle teema domineerivat käsitlust ja pildilist kuvamist, luues naiskunstnikuna uue vaatenurga

  10. E-tervishoiust on abi kõigile / Kai Ilustrumm

    Index Scriptorium Estoniae

    Ilustrumm, Kai

    2004-01-01

    Vt. ka Linnaleht : Pärnu : Tehnika, Linnaleht : Tartu : Tehnika 5. nov., lk. 10. Ida-Tallinna Keskhaigla on haaratud Taani, Norra, Rootsi, Eesti ja Leedu tervishoiualasesse koostööprojekti Baltic eHealth ehk Balti e-tervishoid. Ida-Tallinna Keskhaiglasse rajatakse rahvusvaheline radioloogiakeskus

  11. Noore õpetaja stardiraha tekitab kultuurikomisjonis vaidlusi / Kai Kalamees

    Index Scriptorium Estoniae

    Kalamees, Kai

    2007-01-01

    24. oktoobril esimese lugemise läbinud eelnõu, mis tagab 2008. aasta 1. septembrist esimest korda koolis tööd alustavatele õpetajatele stardiraha, jõuab uuesti riigikogu ette detsembris. Tallinna Ülikoolis kolmandal kursusel klassiõpetajaks õppiv Helen Tuga seob oma tuleviku õpetajatööga ka ilma riigi antava 200 000 kroonita

  12. Eelarveheitlus sai eile riigikogus vihase avastardi / Kai Kalamees

    Index Scriptorium Estoniae

    Kalamees, Kai

    2004-01-01

    Ilmunud ka: Infopress, 1. okt. 2004, nr. 40, lk. 24. Peaminister Juhan Partsi kõnest Riigikogus 2005. aasta riigieelarve eelnõu üle andes. Riigikogu liikmete hinnanguid eelarve kohta. Diagrammid: Eelarve jõudis riigikokku. Lisa: Riigi tulud tuleval aastal. Kommenteerivad Eiki Nestor, Ain Seppik, Mart Laar

  13. Kaheksas ehtenäitus sel hooajal / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    1999-01-01

    18. VI-8. VIII Tarbekunstimuuseumis rahvusvaheline ehtekunstinäitus "Meele Avaldus/Mind Seduction". Osalema on kutsutud 30 noort ehtekunstnikku seitsmest Euroopa riigist. Kuraator ja kujundaja Ketli Tiitsar. Eestit esindavad rühmituse F.F.F.F. liikmed, Mari ja Adolfas Shaulys

  14. Lovgoi kai; e[rga : Thucydides and His Speeches

    Directory of Open Access Journals (Sweden)

    Gregor Pobežin

    2006-12-01

    Full Text Available The paper deals with some problems posed by the study of speeches in Thucydides' History of the Peloponnesian War, especially those that result from seeking the so-called historical truth. The historical value of the speeches, which show the unmistakable influence of forensic oratory, has been subject to various interpretations. The efforts seem to be epitomised by the search for an adequate explanation of the so-called “methodological” chapter 1.22, especially the sentence 1.22.1, which has been identified as the most crucial for a proper understanding of Thucydides' use of speeches: wJ~ dÆ a]n ejdovkoun moi e{kastoi peri; tw`n ajei; parovntwn ta; devonta mavlistÆ eijpei`n, ejcomevnw/ o{ti ejgguvtata th`~ xumpavsh~ gnwvmh~ tw`n ajlhqw`~ lecqevntwn, ou{tw~ ei[rhtai . It seems absolutely imperative that this sentence be understood as an authorial manifesto, a statement of the use and arrangement of speeches in the work. To deny the author even the minimum of historical ambition in the speeches included, thus reducing the entire account to a work of largely fictional value, seems highly inadequate. The paper therefore contends that, while there is no actual proof that the speeches available to the reader were recorded in their spoken form (in fact, judging from the term th`~ xumpavsh~ gnwvmh~ , their length may well have been adapted to the needs of a historical narrative, there is similarly no ground for denying their basic historical substance.

  15. Riigikogu laiendab eripensioni saavate ametiisikute ringi / Kai Kalamees

    Index Scriptorium Estoniae

    Kalamees, Kai

    2007-01-01

    Tolliseaduse muutmise eelnõust, millega loetakse alates 1. jaanuarist 2008 eripensioni saajate hulka ka tolliametnikud, kes teenisid 1990-1994 majandus- või riigipiiril ja kellel on 31. detsembriks täitunud teenistusstaazhi 20 aastat

  16. Koolipingist ärisse / Kai Väärtnõu

    Index Scriptorium Estoniae

    Väärtnõu, Kai

    2004-01-01

    Õpilasfirmade Neli Poega ja R@t tegevusest ja saavutustest Euroopa õpilasfirmade võistlustel. Õpilasfirmade tegevust koordineeriva Junior Achievement'i arengufondi tegevdirektor Epp Lauk ja nõukogu esimees Rein Loik kinnitavad, et ettevõtjad ja riik on hakanud ettevõtlusharidust hindama. Kommenteerib Karoli Hindriks

  17. Millises suunas arened, Pärnu linn? / Maie Kais

    Index Scriptorium Estoniae

    Kais, Maie, 1950-

    2003-01-01

    Uue üldplaneeringu kehtestamisest septembris 2001 kuni käesoleva ajani kehtestatud detailplaneeringutest. Korruselamu kerkimisest kesklinna väikeelamute keskkonda, ranna-alast, nelja korruselamu ehitamisest Rannahotelli vahetusse naabrusesse, hotelli ehitamisest Rannakohviku ja -hotelli vahelisele pargialale, liikluskorraldusest rannas ja ranna lähialadel, Seedri t. villade piiretest jm.

  18. Koostöös Eesti Instituudiga korraldas...

    Index Scriptorium Estoniae

    2004-01-01

    Katariina Gild korraldas Prantsusmaal kaks näitust: 4.-16. XI Tours'i eeslinnas Saint-Cyr-sur-Loire'i Charles X paviljonis ning 19.-30. XI Loches'i linnas. Näituse kujundasid Kaire Tali ja Krista Laos, eksponeeritud olid Kai Koppeli, Viivi-Ann Keerdo, Ülle Rajasalu, Virve Kermi, Kaire Tali, Pille Kivihalli, Jane Rannametsa, Anni Kreemi, Ene Parsi, Liivia Leshkini, Ülle Kõutsi ja Krista Laose tööd.

  19. Levitikus as agtergrond van Markus 5:25–34, geïnterpreteer in terme ...

    African Journals Online (AJOL)

    2 Feb 2011 ... is nie onrein nie, want dit is normaal dat daar mis sal wees daar waar koeie beweeg; dit is dus in plek. Wanneer hierdie ... mis voor in die huis, 'n plek voor waar dit nie hoort nie en dan is dit onrein. Onreinheid verwys ..... die shalom kan ervaar wat haar so lank ontneem was. kai. i;sqi u`gih.j avpo. th/j ma ...

  20. Chaining for Flexible and High-Performance Key-Value Systems

    Science.gov (United States)

    2012-09-01

    27] Fay Chang, Jeffrey Dean, Sanjay Ghemawat, Wilson C. Hsieh , Deborah A. Wallach, Mike Burrows, Tushar Chandra, Andrew Fikes, and Robert E. Gruber...70, 93 and 99.] 106 [40] Fred Douglis, Frans Kaashoek, Brian Marsh, Ramon Caceres, Kai Li, and Joshua Tauber. Storage alternatives for mobile...1994. [Cited on page 92.] [109] Haifeng Yu and Amin Vahdat. Design and evaluation of a continuous consistency model for replicated services. In

  1. Different Styles for Different Needs – The Effect of Cognitive Styles on Idea Generation

    OpenAIRE

    Lomberg, Carina; Kollmann, Tobias; Stockmann, Christoph

    2017-01-01

    Researchers are engaged in finding the precursors for innovation. Drawing on Kirton's Adaption-Innovation (KAI) Inventory, we explicitly test Kirton's central premise that cognitive styles differentiate between preferences for producing ideas in a certain way. We argue that the generation of either a magnitude or original ideas is governed by different underlying cognitive styles. In a study with 191 individuals, we find that the cognitive style originality associates with ideational fluency ...

  2. Operating Below Crush Depth: The Formation, Evolution, and Collapse of the Imperial Japanese Navy Submarine Force in World War II

    Science.gov (United States)

    2011-06-10

    Subamrine, Medium) LCDR Lieutenant Commander LT Lieutenant NM Nautical Mile RADM Rear Admiral ST Sen- Taka (Submarine, High Speed) STo Sen-Toku...Special Submarine) STS Sen- Taka -Sho (Submarine, High Speed(Victory)) USS United States Ship VADM Vice Admiral 1 CHAPTER 1 INTRODUCTION On...Kirai-Sen meaning Mine-Layer, KT for Kai-Toku-Chu meaning Medium, Special Submarine, ST for Sen- Taka meaning Submarine, High speed, STo for Sen Toku

  3. Inspiratsiooni lätetel Amsterdamis : kuhu püüelda ja millest hoiduda... / Eve Koha

    Index Scriptorium Estoniae

    Koha, Eve

    2002-01-01

    Ülemaailmse klaasikunsti ühingu Glass Art Society 32. aastakonverentsist Amsterdamis 30. V-2. VI. Eestist osalesid Viivi-Ann Keerdo, Eve Koha, Kai Koppel, Eeva Käsper-Lennuk, Ivo Lill ja Tiina Sarapu. Näitusel "Young and Hot, European Emerging Artists" esindasid Eestit E. Käsper-Lennuk ja T. Sarapu. Elutööpreemiad ameeriklasele Fritz Dreisbachile (sünd. 1941) ja taanlasele Finn Lynggaardile (sünd. 1939)

  4. Conference on storage in the service of energy transition

    International Nuclear Information System (INIS)

    Leuthold, Matthias; Marchal, David; Sitte, Ralf; Kairies, Kai-Philipp; Guerrier, Pierre; Netzel, Niklas; Radvanyi, Etienne; Lenck, Thorsten

    2016-01-01

    The French-German office for Renewable energies (OFAEnR) organised a conference on energy storage supporting the energy transition in France and in Germany. In the framework of this French-German exchange of experience, about 140 participants met together to debate about the answer of future storage technologies to the electric power system needs and to the optimum integration of renewable energies at different levels of the power transmission and distribution grid. This document brings together the available presentations (slides) made during this event: 1 - Storage Technologies, Status and Perspectives (Matthias Leuthold); 2 - Which electricity storage needs for 2030, 2050 in France? (David Marchal); 3 - Storage in context of the German 'Energiewende' (Ralf Sitte); 4 - Battery Storage for residential PV Systems: Grid relieving effects (Kai-Philipp Kairies); 5 - Battery Storage for residential PV Systems: Technologies and Market Trends (Kai-Philipp Kairies); 6 - Pumped hydro-stations to ensure a decentralized and flexible storage to integrate the best way RES in the electric system (Pierre Guerrier); 7 - RRKW Feldheim - Primary Frequency Control in a wind feed-in grid (Niklas Netzel); 8 - Smoothing an intermittent generation: interest of generation forecast and storage global management (Etienne Radvanyi); 9 - Power-to-gas after 2030 - A cost-benefit analysis (Thorsten Lenck)

  5. Lichen Secondary Metabolite, Physciosporin, Inhibits Lung Cancer Cell Motility

    Science.gov (United States)

    Yang, Yi; Park, So-Yeon; Nguyen, Thanh Thi; Yu, Young Hyun; Nguyen, Tru Van; Sun, Eun Gene; Udeni, Jayalal; Jeong, Min-Hye; Pereira, Iris; Moon, Cheol; Ha, Hyung-Ho; Kim, Kyung Keun; Hur, Jae-Seoun; Kim, Hangun

    2015-01-01

    Lichens produce various unique chemicals that can be used for pharmaceutical purposes. To screen for novel lichen secondary metabolites showing inhibitory activity against lung cancer cell motility, we tested acetone extracts of 13 lichen samples collected in Chile. Physciosporin, isolated from Pseudocyphellaria coriacea (Hook f. & Taylor) D.J. Galloway & P. James, was identified as an effective compound and showed significant inhibitory activity in migration and invasion assays against human lung cancer cells. Physciosporin treatment reduced both protein and mRNA levels of N-cadherin with concomitant decreases in the levels of epithelial-mesenchymal transition markers such as snail and twist. Physciosporin also suppressed KITENIN (KAI1 C-terminal interacting tetraspanin)-mediated AP-1 activity in both the absence and presence of epidermal growth factor stimulation. Quantitative real-time PCR analysis showed that the expression of the metastasis suppressor gene, KAI1, was increased while that of the metastasis enhancer gene, KITENIN, was dramatically decreased by physciosporin. Particularly, the activity of 3’-untranslated region of KITENIN was decreased by physciosporin. Moreover, Cdc42 and Rac1 activities were decreased by physciosporin. These results demonstrated that the lichen secondary metabolite, physciosporin, inhibits lung cancer cell motility through novel mechanisms of action. PMID:26371759

  6. О традициях русской любовной лирики XIX века (Н. Некрасов и Ф. Тютчев | Apie XIX amžiaus meilės lyrikos tradiciją (N. Nekrasovas ir F. Tiutčevas

    Directory of Open Access Journals (Sweden)

    Дагне Бержайте

    2006-01-01

    Full Text Available Intymiąją N. Nekrasovo ir F. Tiutčevo lyriką suartina dialogiškas eilėraščių pobūdis ir kai kurių rusų meilės lyrikos tradicinių motyvų raida (pvz., Puškino „išgyvenimų prisiminimų“ tema. Šie motyvai ir vaizdiniai (pavyduliavimas, kančios, lemtis, laiškai, liepsna neretai įgyja skirtingą plėtotę poetų meilės eilėraščiuose. Straipsnyje pagrindiniu nagrinėjimo objektu yra N. Nekrasovo „Degantys laiškai“ ir F. Tiutčevo „Ji sedėjo ant grindų…“. Šių dviejų tekstų analogija nagrinėjama temos ir vaizdinių lygmenyje. Išanalizuotos personažų (lyrinio subjekto ir herojės lyrinio vyksmo panašybės ir skirtybės. Autorė daro išvadą, kad Nekrasovo meilės lyrika, nepaisant romantinių motyvų pastovumo, artima XIX a. antros pusės rusų psichologinei prozai su jai būdinga griaunančios meilės jėgos tema.

  7. Art, class and gender in Joseon dynasty Korea: representations of lower-class women by the scholar-painter Yun Duseo.

    Science.gov (United States)

    Chung, Saehyang P

    2011-01-01

    This paper examines several pioneering genre paintings by the important scholar painter Yun Duseo (1668-1715), with its focus on their artistic sources which have not yet been explored so far. Painted on ramie, 'Women Picking Potherbs' is one of the most intriguing examples among Yun Duseo's oeuvre, which encompasses a broad variety of themes, including genre imagery, landscapes, portraits, dragons, and horses. Even among Yun Duseo's genre paintings, 'Women Picking Potherbs' is extraordinary, as recent scholarship regards it as the earliest independent representation of lower-class women in the history of Korean art. In particular, Yun Duseo painted two women who were working ourdoors to gather spring potherbs. In a conservative Confucian society, it was extraordinary women who were working outdoors. Hence, Yun Duseo occupies a highly important place in Korean painting. Furthermore, even though Yun Duseo came from the upper-class, he often painted images of lower class people working. It is possible that Yun Duseo was familiar with the book titled "Tian gong kai wu" (Exploitation of the Works of Nature) which was published in the 17th century. By identifying the probable body of his artistic sources in the book known as "Tian gong kai wu," it will be possible to assess the innovations and limitations found in 'Women Picking Potherbs'.

  8. Asterless licenses daughter centrioles to duplicate for the first time in Drosophila embryos.

    Science.gov (United States)

    Novak, Zsofia A; Conduit, Paul T; Wainman, Alan; Raff, Jordan W

    2014-06-02

    Centrioles form centrosomes and cilia, and defects in any of these three organelles are associated with human disease [1]. Centrioles duplicate once per cell cycle, when a mother centriole assembles an adjacent daughter during S phase. Daughter centrioles cannot support the assembly of another daughter until they mature into mothers during the next cell cycle [2-5]. The molecular nature of this daughter-to-mother transition remains mysterious. Pioneering studies in C. elegans identified a set of core proteins essential for centriole duplication [6-12], and a similar set have now been identified in other species [10, 13-18]. The protein kinase ZYG-1/Sak/Plk4 recruits the inner centriole cartwheel components SAS-6 and SAS-5/Ana2/STIL, which then recruit SAS-4/CPAP, which in turn helps assemble the outer centriole microtubules [19, 20]. In flies and humans, the Asterless/Cep152 protein interacts with Sak/Plk4 and Sas-4/CPAP and is required for centriole duplication, although its precise role in the assembly pathway is unclear [21-24]. Here, we show that Asl is not incorporated into daughter centrioles as they assemble during S phase but is only incorporated once mother and daughter separate at the end of mitosis. The initial incorporation of Asterless (Asl) is irreversible, requires DSas-4, and, crucially, is essential for daughter centrioles to mature into mothers that can support centriole duplication. We therefore propose a "dual-licensing" model of centriole duplication, in which Asl incorporation provides a permanent primary license to allow new centrioles to duplicate for the first time, while centriole disengagement provides a reduplication license to allow mother centrioles to duplicate again. Copyright © 2014 The Authors. Published by Elsevier Inc. All rights reserved.

  9. Methane and carbon dioxide exchange in a post-extraction, unrestored peatland in Eastern Quebec, Canada

    Science.gov (United States)

    Rankin, Tracy; Strachan, Ian; Strack, Maria

    2017-04-01

    Peatlands, in their pristine state, are important long-term sinks of carbon. The extraction of peat for agricultural purposes or for biofuel leads to a shift in the carbon dynamics. Changes in environmental conditions post extraction may also allow for invasive species to establish and spread across the peatland. Many studies have shown the benefits and advantages of various restoration management practices, but few studies have explored the carbon exchange from unrestored peatlands. Our study reports the methane (CH4) and carbon dioxide (CO2) fluxes from a post-extraction, unrestored peatland in Eastern Québec at both the plant community scale using static chambers, and at the ecosystem scale using an eddy covariance flux tower, over two complete years. Extraction of the Saint-Alexandre-de-Kamouraska peatland (SAK) started in the early 1970's and was halted in 1999. No restoration efforts have been implemented and the remnant ditches remain unblocked. The site consists of sparse patches of Eriophorum and a vast area of bare peat. Consequently, SAK is an overall source of carbon to the atmosphere, releasing an annual total of 153 g C m-2 and 241 g C m-2 in CO2 emissions for 2014 and 2015, respectively, and an average annual total of 1 g C m-2yr-1 in CH4 emissions. Phragmites and Typha, both invasive species, have established themselves in the ditches and are sources of methane; partly explaining the increased emissions in carbon fluxes to the atmosphere post extraction. Results from this study will help managers assess the importance of post-extraction peatland restoration, by comparing the differences in CO2 and CH4 exchange between restored and unrestored peatlands.

  10. Selection indicates preference in diverse habitats: a ground-nesting bird (Charadrius melodus using reservoir shoreline.

    Directory of Open Access Journals (Sweden)

    Michael J Anteau

    Full Text Available Animals use proximate cues to select resources that maximize individual fitness. When animals have a diverse array of available habitats, those selected could give insights into true habitat preferences. Since the construction of the Garrison Dam on the Missouri River in North Dakota, Lake Sakakawea (SAK has become an important breeding area for federally threatened piping plovers (Charadrius melodus; hereafter plovers. We used conditional logistic regression to examine nest-site selection at fine scales (1, 3, and 10 m during summers 2006-2009 by comparing characteristics at 351 nests to those of 668 random sites within nesting territories. Plovers selected sites (1 m(2 that were lower than unused random sites, increasing the risk of nest inundation. Plovers selected nest sites that were flat, had little silt, and at least 1 cobble; they also selected for 3-m radius nest areas that were relatively flat and devoid of vegetation and litter. Ninety percent of nests had <38% coverage of silt and <10% slope at the site, and <15% coverage of vegetation or litter and <31% slope within the 3-m radius. Gravel was selected for at nest sites (11% median, but against in the area 10-m from the nest, suggesting plovers select for patches or strips of gravel. Although elevation is rarely evaluated in studies of ground-nesting birds, our results underscore its importance in habitat-selection studies. Relative to where plovers historically nested, habitat at SAK has more diverse topography, substrate composition, vegetation communities, and greater water-level fluctuations. Accordingly, our results provide an example of how habitat-selection results can be interpreted as habitat preferences because they are not influenced by desired habitats being scarce or absent. Further, our results will be useful for directing habitat conservation for plovers and interpreting other habitat-selection studies.

  11. Alaska North Slope National Energy Strategy initiative: Analysis of five undeveloped fields

    International Nuclear Information System (INIS)

    Thomas, C.P.; Allaire, R.B.; Doughty, T.C.; Faulder, D.D.; Irving, J.S.; Jamison, H.C.; White, G.J.

    1993-05-01

    The US Department of Energy was directed in the National Energy Strategy to establish a federal interagency task force to identify specific technical and regulatory barriers to the development of five undeveloped North Slope Alaska fields and make recommendations for their resolution. The five fields are West Sak, Point Thomson, Gwydyr Bay, Seal Island/Northstar, and Sandpiper Island. Analysis of environmental, regulatory, technical, and economic information, and data relating to the development potential of the five fields leads to the following conclusions: Development of the five fields would result in an estimated total of 1,055 million barrels of oil and 4.4 trillion cubic feet of natural gas and total investment of $9.4 billion in 1992 dollars. It appears that all five of the fields will remain economically marginal developments unless there is significant improvement in world oil prices. Costs of regulatory compliance and mitigation, and costs to reduce or maintain environmental impacts at acceptable levels influence project investments and operating costs and must be considered in the development decision making process. The development of three of the fields (West Sak, Point Thomson, and Gwydyr Bay) that are marginally feasible would have an impact on North Slope production over the period from about 2000 to 2014 but cannot replace the decline in Prudhoe Bay Unit production or maintain the operation of the Trans-Alaska Pipeline System (TAPS) beyond about 2014 with the assumption that the TAPS will shut down when production declines to the range of 400 to 200 thousand barrels of oil/day. Recoverable reserves left in the ground in the currently producing fields and soon to be developed fields, Niakuk and Point McIntyre, would range from 1 billion to 500 million barrels of oil corresponding to the time period of 2008 to 2014 based on the TAPS shutdown assumption

  12. Alaska North Slope National Energy Strategy initiative: Analysis of five undeveloped fields

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, C.P.; Allaire, R.B.; Doughty, T.C.; Faulder, D.D.; Irving, J.S.; Jamison, H.C.; White, G.J.

    1993-05-01

    The US Department of Energy was directed in the National Energy Strategy to establish a federal interagency task force to identify specific technical and regulatory barriers to the development of five undeveloped North Slope Alaska fields and make recommendations for their resolution. The five fields are West Sak, Point Thomson, Gwydyr Bay, Seal Island/Northstar, and Sandpiper Island. Analysis of environmental, regulatory, technical, and economic information, and data relating to the development potential of the five fields leads to the following conclusions: Development of the five fields would result in an estimated total of 1,055 million barrels of oil and 4.4 trillion cubic feet of natural gas and total investment of $9.4 billion in 1992 dollars. It appears that all five of the fields will remain economically marginal developments unless there is significant improvement in world oil prices. Costs of regulatory compliance and mitigation, and costs to reduce or maintain environmental impacts at acceptable levels influence project investments and operating costs and must be considered in the development decision making process. The development of three of the fields (West Sak, Point Thomson, and Gwydyr Bay) that are marginally feasible would have an impact on North Slope production over the period from about 2000 to 2014 but cannot replace the decline in Prudhoe Bay Unit production or maintain the operation of the Trans-Alaska Pipeline System (TAPS) beyond about 2014 with the assumption that the TAPS will shut down when production declines to the range of 400 to 200 thousand barrels of oil/day. Recoverable reserves left in the ground in the currently producing fields and soon to be developed fields, Niakuk and Point McIntyre, would range from 1 billion to 500 million barrels of oil corresponding to the time period of 2008 to 2014 based on the TAPS shutdown assumption.

  13. El léxico cromático y la ideología maya Chromatic lexic and Maya ideology

    Directory of Open Access Journals (Sweden)

    Sanja Savkic

    2011-01-01

    Full Text Available Para acercarse al campo semántico de los colores, de primera importancia son diversos diccionarios de las lenguas mayances. El objetivo es hacer una descripción preliminar del vocabulario cromático, compuesto de cinco términos referidos a colores básicos que en el maya yucateco se llaman sak, ek', chak, k'an y ya'ax y significan "blanco", "negro", "rojo", "amarillo" y "verde-azul", respectivamente. El mismo vocabulario remite a determinadas categorías extralingüísticas que la lengua es capaz de acumular, reflejar y comunicar. Éstas dependen de una cultura particular, por lo que el estudio se amplía con las informaciones de diferentes fuentes escritas redactadas durante la época colonial. La intención es detectar los múltiples usos que se hacían en todos los ámbitos de la vida de los colores, lo cual a su vez permite considerar estos últimos como conceptualizaciones articuladas en pares de oposición o agrupamientos tripartitos.To gain greater insight into the color semantic field, it is important to consult various Mayance language dictionaries, in order to assemble a preliminary chromatic vocabulary, composed of five basic color terms which in Yucatec Maya are sak, ek', chak, k'an and ya'ax, or "white", "black", "red", "yellow" and "green-blue", respectively. The very vocabulary addresses certain extra-linguistic categories that language is capable of accumulating, reflecting, and communicating. These categories depend on a particular culture; consequently this study is amplified with greater information from different sources written during the colonial period in order to shed light on the many uses that the colors had in the aspects of human life which, at the same time, can be seen in conceptualizations articulated in pairs of opposition or tripartite groupings.

  14. On aeg mängida! / Ell-Maaja Randküla

    Index Scriptorium Estoniae

    Randküla, Ell-Maaja, 1939-2016

    2005-01-01

    Tartu Mänguasjamuuseumi (Tartu, Lutsu t. 8) sisekujundus. Autorid: Tea Tammelaan, Krista Lepland, Malle Jürgenson, OÜ Laika, Belka & Strelka. Maalitud põrandavaip: Kai Kaljo. Maalitud pitslinad: Tuuli Puhvel. Ehitaja: AS Facio Ehitus. Eesti Sisearhitektide Liidu 2004. a. aastapreemiate konkursil pälvis ajaloolise interjööri preemia. T. Tammelaanest, K. Leplandist ja M. Jürgensonist, OÜ Laika, Belka & Strelka tähtsamad tööd. Ill.: plaan, 23 värv. vaadet

  15. Redefining the Moral and Legal Roles of the State in Everyday Life: The New Life Movement in China in the Mid-1930s

    OpenAIRE

    Wennan Liu

    2013-01-01

    Chiang Kai-shek launched the New Life Movement in Nanchang in February 1934 to revive traditional morality by reforming people’s daily behavior. In response to civil leader Wang Jingwei’s challenge, Chiang agreed to deploy moral suasion to urge the Chinese people to observe the New Life directives, but he still integrated the movement into government routine and relied on government agents, especially policemen, to implement it. Contemporary politicians and commentators understood this moveme...

  16. Into the Eye of the Commander: Military Advisory During Conflict

    Science.gov (United States)

    2011-03-16

    Northeast 3 Asia. First, China continued to struggle through a bloody civil war between Chiang Kai- shek‘s Nationalists and Mao Tse -tung‘s Communist...Indochina into Cambodia and Laos and further sub-divided Vietnam along the 17th Parallel into a communist north and a democratic 9 south. The...insurgencies in Laos and South Vietnam had begun to take an ominous turn. Fearing both nuclear and conventional parity with the Soviet Union

  17. Feinkartierung von Loss of Heterozygosity-Intervallen auf Chromosom 11p und Untersuchungen zum Expressions- und Methylierungsstatus von FANCF beim Ovarialkarzinom

    OpenAIRE

    Schulze, Kathrin

    2011-01-01

    Um Tumorsuppressorgene beim Ovarialkarzinom zu identifizieren wurde eine Kartierung von LOH-Intervallen der Region 11p15.5 - 11p11.2 mittels 11 Mikrosatellitenmarkern an 47 Ovarialtumorproben vorgenommen. Im Bereich des ST5- und AFM255/KAI1-Locus konnten potentielle Intervalle abgegrenzt werden. Das Fanconi Anämie Gen FANCF wurde für Untersuchungen zum Expressions- und Methylierungsstatus ausgewählt, da dessen Abschaltung mit einem besseren Ansprechen auf Cisplatin bei Ovarialkarzinompatienti...

  18. Gas Warfare in World War I. The 3rd. Division at Chateau Thierry, July 1918

    Science.gov (United States)

    1959-07-01

    I hvt ’.o 1, 17 Jun (Vb, i p. 35 - 36’. 1Jnf.-D>in -i. 10. 1andý’er:Divu i -@Una 5O~fg opv ~lGe vns me., 44 %~ Aw sw1 .~.g P.. 9.s KAi,, .I P LAM... indoors (where delay in masking or escaping to the open was almost certain to rqsult in casualties]. Shell fire and a general sense of insecurity

  19. MONTAGE: A Methodology for Designing Composable End-to-End Secure Distributed Systems

    Science.gov (United States)

    2012-08-01

    and verification, from PSOS [NF03] to the recent seL4 [KEH+09]. While they make considerable progress toward high-assurance OS, these works are not...of the specification itself. Examples include the seL4 microkernel work by Klein et al. [KEH+09], which presents the experience of formally proving...David Cock, Philip Derrin, Dhammika Elkaduwe, Kai Engelhardt, Rafal Kolanski, Michael Norrish, Thomas Sewell, Harvey Tuch, and Simon Winwood. sel4

  20. Enkele gedagtes oor Matteus se gebruikmaking van die Ou ...

    African Journals Online (AJOL)

    Testament immers geensins op 'n eenvormige manier nie. Om hierdie ... kai en ekei héds tës teleutës Hërodou hína plërdthë tó rhêthén hupd kurtou diá ... evangelis 'n duidelike verband tussen Herodes en Farao se kinder- moorde trek, val die duidelike toespeling op Eksodus 4:19-20 in vers. 20 nie te ontken nie. Daar is 'n ...

  1. Lietuvos Respublikos savivaldybių komunikacija socialiniame tinkle „Facebook“

    OpenAIRE

    Blinstrubas, Mantas

    2014-01-01

    Bakalauro baigiamajame darbe nagrinėjama Lietuvos Respublikos savivaldybių komunikacija Lietuvoje ir pasaulyje populiariausiame socialiniame tinkle „Facebook“. Savivaldybė šio tyrimo rėmuose traktuojama kaip teritoriškai determinuota bendruomenė ir kaip vietos valdžios organas. Ataskaitoje pristatomo tyrimo problema išreiškiama klausimais „Kokia yra viešojo administravimo institucijų komunikacijos socialiniuose tinkluose specifika? Kokia yra Lietuvos Respublikos savivaldybių komunikacijos soc...

  2. 27. ja 28. IX toimus Narvas VII Eesti muuseumide näituste festival ja seminar

    Index Scriptorium Estoniae

    2004-01-01

    I koha pälvis ERMi ja Adamson-Ericu muuseumi koostööprojekt "Viinapuuväät. Maasikakiri II" (kontseptsiooni ja haridusprogrammi autorid Vaike Reemann, Ülle Kruus, Kersti Koll ja Kai Tuvik, kujundaja Denes Farkas, monteerija Vahur Puik), II - Tartu Kunstimuuseumi näitus "Muuseum muuseumis" (kontseptsiooni autorid ja teostajad Ahti Seppet, Hannes Varblane), III - Viljandi muuseumi näitus "Rõõmud lumel ja jääl" (idee autor Herki Helves)

  3. Network Intrusion Dataset Assessment

    Science.gov (United States)

    2013-03-01

    International Conference on Computational Intelligence and Natural Computing, volume 2, pages 413–416, June 2009. • Rung Ching Chen, Kai -Fan Cheng, and...Chia-Fen Hsieh . “Using rough set and support vector machine for network intrusion detection.” International Journal of Network Security & Its...intrusion detection using FP tree rules.” Journal Of Advanced Networking and Applications, 1(1):30–39, 2009. • Ming-Yang Su, Gwo-Jong Yu , and Chun-Yuen

  4. Innovative behavior in nurse executives.

    Science.gov (United States)

    Adams, C E

    1994-05-01

    This study addresses the problem-solving styles of hospital nurse executives and explores the relationship between problem-solving style and leader effectiveness. The Kirton Adaption-Innovation Inventory (KAI) and the Leader Effectiveness and Adaptability Description-Self (LEAD-S) were the instruments used to survey nurse executives from 66 medium-sized urban California hospitals. The majority of respondents used innovative approaches, but no correlation was found between problem-solving style and leader effectiveness.

  5. Predictability of the individual clinical outcome of extracorporeal shock wave therapy for cellulite

    OpenAIRE

    Schlaudraff, Kai-Uwe; Kiessling, Maren C; Császár, Nikolaus BM; Schmitz, Christoph

    2014-01-01

    Kai-Uwe Schlaudraff,1 Maren C Kiessling,2 Nikolaus BM Császár,2 Christoph Schmitz21Concept Clinic, Geneva, Switzerland; 2Department of Anatomy II, Ludwig-Maximilians-University of Munich, Munich, GermanyBackground: Extracorporeal shock wave therapy has been successfully introduced for the treatment of cellulite in recent years. However, it is still unknown whether the individual clinical outcome of cellulite treatment with extracorporeal shock wave therapy can be predict...

  6. Contract W911NF-09-1-0384 (Purdue University)

    Science.gov (United States)

    2012-10-27

    spin system, Physical Review A , (02 2010): 22324. doi: 10.1103/PhysRevA.81.022324 08/31/2011 8.00 Sabre Kais, Anmer Daskin . Group leaders... a collection of information if it does not display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. a ...billions ) and developed new quantum algorithms to solve complex chemistry problems such as global optimization and excited states of molecules. ( a ) Papers

  7. Mustamäe Maarja Magdaleena kiriku arhitektuurivõistlus = Architecture competition for Mustamäe`s Church of Mary Magdalene / Pille Epner

    Index Scriptorium Estoniae

    Epner, Pille

    2013-01-01

    Arhitektuurikonkursist, võidutööst "Fiat Lux" (arhitektid Risto Parve, Kai Süda, Martin Kinks, Margit Valma, arhitektuuriteadlane Mait Väljas, Karisma Arhitektid), 2. koha pälvinud tööst "Õhuke Koht" (Pille Noole, Üllar Ambos, Kaisa Lasner, Kerttu Karjust, Jiannis Lykouras, Arhitektuurinurk), 3. koha pälvinud tööst "Tee" (Villem Tomiste, Stuudio Tallinn). Loetletud ostupreemia ja kolm tunnustuse pälvinud võistlustööd

  8. Corruption in Conflict: Lessons from the U.S. Experience in Afghanistan

    Science.gov (United States)

    2016-09-01

    United States Toll- free : 866-329-8893 DSN: 312-664-0378 All voicemail is in English and answered during business hours. By fax: 703-601-4065 By email...efforts: Chiang Kai-shek’s counterinsurgency against Mao Zedong in China, the British counterinsurgency in Malaysia , and the U.S.-trained South...accept abuse of power, corruption, or marginalization.”232 Similar messages were appearing across the U.S. government. In his 2009 speech on the Af

  9. Japan does it mainly compact and flexible: Innovate improvements in the natural gas distribution technique and gas appliances

    International Nuclear Information System (INIS)

    Roebers, H.

    1994-01-01

    Specific Japanese innovative improvements in natural gas distribution systems and natural gas appliances are outlined, based on the KAI-ZEN philosophy. Attention is paid to the design of flexible gas pipes, gas plug-in sockets, and safety systems, and the compact design of gas appliances. Much of the innovations focus on details. Briefly, the NEXT 21 project is described, which project anticipates the silent wishes of the Japanese people with regard to lifestyle

  10. Kiviõli linnaväljaku avalik arhitektuurivõistlus = Kiviõli town square open architecture competition / Tiit Sild

    Index Scriptorium Estoniae

    Sild, Tiit, 1977-

    2006-01-01

    Arhitektuurivõistluse eesmärgist, premeeritud töödest. Tulemused: I preemia - Tiina Skolimowski, Kai Süda, Risto Parve, töö "Figuur", II - Karli Luik, Ralf Lõoke, Maarja Kask (AB Salto), töö "Saarestik", III - Jaak-Adam Looveer, Toomas Paaver, Lauri Saar, Indrek Järve, Tõnu Laanemäe (AB Paik Arhitektid), töö "Mult", ergutuspreemia - Ott Kadarik, Villem Tomiste, Mihkel Tüür, Kaiko Kivi, Krista Saluveer (AB Kosmos), töö "Sammal"

  11. Implicitly Defined Neural Networks for Sequence Labeling

    Science.gov (United States)

    2017-07-31

    ularity has soared for the Long Short - Term Memory (LSTM) (Hochreiter and Schmidhuber, 1997) and vari- ants such as Gated Recurrent Unit (GRU) (Cho et...610. Sepp Hochreiter and Jürgen Schmidhuber. 1997. Long short - term memory . Neural computation 9(8):1735– 1780. Zhiheng Huang, Wei Xu, and Kai Yu. 2015...network are coupled together, in order to improve perfor- mance on complex, long -range dependencies in either direction of a sequence. We contrast our

  12. RELATIONSHIP BETWEEN KNOWLEDGE ABOUT CLIMATE CHANGE ISSUES AND LOCUS OF CONTROL WITH STUDENTS’ CITIZENSHIP BEHAVIOR

    OpenAIRE

    Fatria, Erian

    2017-01-01

    Needless to say that environmental deterioration is brought about by the people intervention toward a nature. It has been assumed that people personality and intelligent influence the ecosystem. That is why the objective of this study is to find out relationship between knowledge about issues (KAI) and Locus of Control (LOC) with citizenship behavior (CB). In order meet with this objective, a survey method has been applied by involving 110 students as sample. There are three instruments, meas...

  13. Management of Bottom Sediments Containing Toxic Substances: Proceedings of the U.S./Japan Experts Meetings (15th) Held in San Pedro, California on 19-21 November 1991

    Science.gov (United States)

    1994-05-01

    on Economic Development, which will convene in Rio de Janeiro in June of 1992, will be the next major forum at which this issue may surface for...1985. Coastal oceanography of Japan Islands. Tokai University Shuppan-kai, viii+8+353 pp. (in Japanese). Otsuki, T. 1990. Jinko lagoon . Umetate to...for acclima- tion. It also took 100 days for the test to get the expected water quality with performing de -nitrogen treatment by reducing airflow of

  14. Osteogenic capacity of nanocrystalline bone cement in a weight-bearing defect at the ovine tibial metaphysis

    OpenAIRE

    Harms, Christoph; Helms,; Taschner,; Stratos,; Ignatius,; Gerber,Thomas; Lenz,; Rammelt,; Vollmar,Brigitte; Mittlmeier,Thomas

    2012-01-01

    Christoph Harms,1 Kai Helms,1 Tibor Taschner,1 Ioannis Stratos,1 Anita Ignatius,5 Thomas Gerber,2 Solvig Lenz,3 Stefan Rammelt,6 Brigitte Vollmar,4 Thomas Mittlmeier11Department of Trauma and Reconstructive Surgery, 2Department for Materials Research and Nanostructures, Institute for Physics, 3Department of Oral and Maxillofacial Plastic Surgery, 4Institute for Experimental Surgery, University of Rostock, Rostock, 5Institute of Orthopaedic Research and Biomechanics, University of Ulm, Ulm, 6C...

  15. Algorithms for Large-Scale Astronomical Problems

    Science.gov (United States)

    2013-08-01

    Magana, Ross O’Connell, Xiaoying Xu, and Feng Yu . They are very nice and provided a lot of useful information. During these years I have worked with...Sicun Gao, Fan Guo, Yunchuan Kong, Ni Lao, Lei Li, Nan Li, Jialiu Lin, Yuefeng Lin, Xi Liu, Ning Lu, Min Luo, Kai Ren, Chao Shen, Long Qin, Huimin... Hsieh , Deborah A. Wallach, Mike Burrows, Tushar Chandra, Andrew Fikes, and Robert E. Gruber. Bigtable: A distributed storage system for structured data

  16. Jätkusuutlikkusest tervisesektoris / Tiit Siinmaa

    Index Scriptorium Estoniae

    Siinmaa, Tiit

    2005-01-01

    Ülevaade 24. novembril 2005. a. Tallinnas Salme kultuurikeskuses toimunud tervisefoorumi "Eesti tervisesüsteemi arengud ja väljakutsed" kolmanda sessiooni ettekannetest. Esinesid Maailma Tervishoiuorganisatsiooni Euroopa regionaalse kontori tervisesüsteemide finantseerimise regionaalnõunik Joseph Kutzin, Singapuri ülikooli tervisepoliitika ja -juhtimise professor Kai Hong Phua, rahandusministeeriumi finantspoliitika asekantsler Veiko Tali, sotsiaalministeeriumi terviseala asekantsler Ivi Normet, Tervise Arengu Instituudi arenduskeskuse juhataja kt Aljona Kurbatova ja Euroopa Rahvatervise Assotsiatsiooni juhtkomitee liige dr Anu Kasmel. Lisatud statistilised tabelid ja diagrammid

  17. Sustained release of bactericidal concentrations of penicillin in the pleural space via an antibiotic-eluting pigtail catheter coated with electrospun nanofibers: results from in vivo and in vitro studies

    OpenAIRE

    Chao, Yin-Kai; Lee, Cheng-Hung; Liu, Kuo-Sheng; Wang, Yi-Chuan; Wang, Chih-Wei; Liu, Shih-Jung

    2015-01-01

    Yin-Kai Chao,1 Cheng-Hung Lee,2 Kuo-Sheng Liu,1 Yi-Chuan Wang,3 Chih-Wei Wang,4 Shih-Jung Liu3 1Department of Thoracic and Cardiovascular Surgery, Chang Gung Memorial Hospital-Linkou, College of Medicine, Chang Gung University, Taoyuan, Taiwan; 2Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital-Linkou, College of Medicine, Chang Gung University, Taoyuan, Taiwan; 3Department of Mechanical Engineering, Chang Gung University, Taoyuan, Taiwan; 4Department of P...

  18. Sensory integration dysfunction affects efficacy of speech therapy on children with functional articulation disorders

    OpenAIRE

    Tung, Li-Chen; Lin, Chin-Kai; Hsieh, Ching-Lin; Chen, Ching-Chi; Huang, Chin-Tsan; Wang, Chun-Hou

    2013-01-01

    Li-Chen Tung,1,# Chin-Kai Lin,2,# Ching-Lin Hsieh,3,4 Ching-Chi Chen,1 Chin-Tsan Huang,1 Chun-Hou Wang5,6 1Department of Physical Medicine and Rehabilitation, Chi Mei Medical Center, Tainan, 2Program of Early Intervention, Department of Early Childhood Education, National Taichung University of Education, Taichung, 3School of Occupational Therapy, College of Medicine, National Taiwan University, Taipei, 4Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, ...

  19. Metaphilosophy, Pragmatism and a Kind of Critical Theory: Kai ...

    African Journals Online (AJOL)

    For Rorty it is historical narrative and utopian proposals; for Nielsen it is critical theory. Rorty claims this, Nielsen's intentions to the contrary notwithstanding, commits him to enlightenment rationalism. Nielsen replies that his form of critical theory is deeply historicist and contextual without being resolutely atheoretical.

  20. Kai kurie teoriniai morfologinės akcentologijos koncepcijos aspektai

    Directory of Open Access Journals (Sweden)

    Vytautas Rinkevičius

    2011-12-01

    Full Text Available EINIGE THEORETISCHE ASPEKTE DER MORPHOLOGISCHEN AKZENTOLOGIEKONZEPTIONZusammenfassungDie im Aufsatz vorgelegte vergleichende Übersicht einiger theoretischer Aspekte der den Prinzipien der morphologischen Akzentologiekonzeption folgenden Werke zur balto-slavischen Akzentologie hat gewisse offensichtliche Nichtübereinstimmungen und Widersprüche, die zwar auf ersten Blick keine Aufmerksamkeit erregen könnten, verdeutlicht. Erkenntnis dieser Widersprüche ist notwendig, um das Wesentliche der morphologischen Akzentologiekonzeption richtig zu verstehen, und sehr wichtig, um sich auf Errungenschaften der früheren Forscher in zukünftigen Untersuchungen zu stützen.Die Konzeptionen der verschiedenen Autoren zur akzentologischen Klassifikation der Morpheme enthalten die Mehrheit der terminologischen Widersprüche. Am stärksten irreführend ist der Begriff Domination, der von einigen Autoren als das Vermögen des Morphems den Akzent zu erhalten, d.h. die Akzentstärke (Dybo, von anderen als die Eigenschaft des Derivationsmorphems die Eigenschaften anderer Morpheme des Worts oder nur des Stamms nicht zu berücksichtigen (Garde, Zaliznjak, von noch anderen als die Eigenschaft des Derivationsmorphems, die Akzentkraft (den Akzentwert des Ableitungsstamms vorherzubestimmen (Stundžia, Pakerys, verstanden wird. Durch den weniger problematischen Terminus Rezessivität kann das Unvermögen des Morphems, den Akzent zu erhalten, d.h. die Akzentschwäche (Dybo, die Eigenschaft des Morphems, die Betonung der ersten Silbe des Worts vorherzubestimmen (Garde 1968, oder auch die Betonung der ersten Silbe in einem Wort, das nur schwache Morpheme enthält (Jakobson, Garde 1980, bezeichnet werden. Akzentstelle kann die Realisierung des Akzents des Morphems durch die Betonung einer bestimmten Silbe des Worts (Garde, Zaliznjak oder die Stellung des akzentuierten Morphems in Beziehung zum unakzentuierten Morphem (Stundžia darstellen. Nicht eindeutig ist auch der Ausdruck Akzentkraft, der manchmal das verallgemeinerte Vermögen des Morphems, die Akzentstelle des Worts zu bestimmen (Garde 1968, entspricht dem Akzentwert von Girdenis, manchmal das Vermögen der Morpheme, akzentuiert oder unakzentuiert zu sein (Garde 1978, Stundžia 1995, entspricht dem Akzentwert von Stundžia 2009 und der Akzentvalenz von Dybo, manchmal die Einwirkung des Derivationsmorphems auf Akzenteigenschaften des Ableitungsstamms (Stundžia 2009 bezeichnet.Das Akzentparadigma ist am besten als eine Klasse von Wörtern mit gleichen Akzenteigenschaften der Stämme zu verstehen und für die Grundlage der akzentologischen Klassifikation der Wörter in Sprachen, in denen Unterschiede zwischen Akzentuierung der zu einem Akzentparadigma gehörenden Wörter nur von ihrer Zugehörigkeit zu verschiedenen grammatischen Klassen abhängig ist (z.B. Litauisch, zu halten. In Sprachen, wo zu einer grammatischen Klasse gehörende Wörter mit gleichen Akzenteigenschaften der Stämme unterschiedlich akzentuiert werden können (z.B. Russisch, ist es bequemer, das Akzentschema (die Akzentkurve, das als Klasse der Wörter mit genau übereinstimmenden Distributionen der Stamm- und Endungsakzentuierten Formen definiert werden kann, für die Grundlage solcher Klassifikation zu halten. Akzentschemata können nach bestimmten Ähnlichkeitsmerkmalen zu größeren Makroklassen angeordnet werden, aber die letzteren dürfen nicht mit den Akzentparadigmen (nach der obigen Definition verwirrt werden. Solche Makroklassen, wie auch alle anderen nötigenfalls besprochenen Akzentklassen, können mit dem Begriff Akzenttyp, der noch keine in der wissenschaftlichen Literatur geregelte Bedeutung hat, benannt werden. Es gibt zwei Methoden der Beschreibung der Akzentuierung der abgeleiteten Wörter: man kann entweder die Akzentstelle der Wörter anhand syntagmatischer Beziehungen zwischen Morphemen (Garde, Zaliznjak, oder die Abhängigkeit der Akzenttypen der Ableitungen von den Akzentparadigmen der Grundwörter (Dybo feststellen. Die letzte Methode verdeutlicht besser die Rolle des Akzents in der Wortbildung und passt besser für historische Akzentologie, weil die Akzentuierung der Ableitungen in den alten baltischen und slavischen Sprachen, wie auch in den Ursprachen, von der Akzentuierung der Grundwörter mehr als in heutigen Sprachen abhängig war. Wichtig für Untersuchungen zur Akzentuierung der abgeleiteten Wörter ist der Begriff Grundstamm (Basiskomponente von Zaliznjak, der den Teil des abgeleiteten Stamms ohne Derivationsmorphem bezeichnet. Der Grundstamm hat seine eigenen Akzenteigenschaften und kann sich formell vom Stamm des Grundworts unterscheiden.Da es nicht nur in den slavischen, sondern auch in den baltischen Sprachen, viele Fälle gibt, wo Klitika — gemeinhin als niemals betonte Wörter definiert — den Akzent erhalten, und Wörter, die als immer betont definiert und traditionell Orthotona genannt werden, den Akzent in Wirklichkeit nicht erhalten, ist in der balto-slavischen Akzentologie (besonders in der historisch-vergleichenden nicht die tatsächliche Akzentuierung, sondern das Vermögen (resp. Unvermögen, eigenständig eine Taktgruppe (ein phonologisches Wort zu bilden, als die Grundlage für die Klassifikation der Wörter nach dem Vermögen, im Redefluß den Akzent zu erhalten, zu betrachten. Wörter können in zwei Klassen eingeteilt werden: Klitika (Wörter, die eine Taktgruppe nicht eigenständig bilden können und akzentogene Wörter (die eine Taktgruppe eigenständig bilden können. Die akzentogenen Wörter können in Orthotona (immer akzentuierte Wörter und Enklinomena (Wörter, die den Akzent an Klitika übergeben eingeteilt werden.

  1. Abort on osa seksuaalkultuuri pärandist / Kai Haldre

    Index Scriptorium Estoniae

    Haldre, Kai, 1965-

    2005-01-01

    Abordikultuuri tekkest Ida-Euroopas ja Nõukogude Liidus ning selle jõudmisest Eestisse. Autori arvates soovimatute raseduste ja uute ilmakodanike vahele ei saa panna võrdusmärki ning abortide arvu vähenemine ei too iseenesest kaasa sündimuse kasvu. Lisa: diagramm

  2. 3,7 miljonit võimalust üksinduseks / Kai Tamm

    Index Scriptorium Estoniae

    Kutman, Kai, 1972-

    2011-01-01

    21. aprillil Berliinis Kulturbrauerei Kesselhausis esietendunud Age Veeroosi ooperist "Grid", libreto autor ja lavastaja Korneel Hamers, dirigent Taavi Kull, videokunstnik Julian bergheim, lavakujunduse autor Julia Rommel. Lk. 17 lühiintervjuu heliloojaga

  3. Katariina kirikus algab Geeniuste mäss / Kai Ilustrumm

    Index Scriptorium Estoniae

    Ilustrumm, Kai

    2004-01-01

    Briti Nõukogu toetusel Pärnus, Tartus ja Tallinnas toimuvatel inglise filmide päevadel "Geeniuste mäss" näidatakse ka 3 Lindsay Andersoni nn. Travise triloogia filmi "Kui..." (1968), "Oo, õnneseen!" (1973) ja "Ravila Britannia" (1982), kus Mick Travise rollis on Malcolm McDowell (1943). Lisatud kava

  4. Ühised juured: Kesk-Euroopa disain Iisraelis / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2012-01-01

    Näitus "Common Roots. Design Map on Central Europe" Holoni disainimuuseumis kuni 23.02.2013. Eestist esindavad nüüdisaegset disaini Sixten Heidmets / Fellin Furniture, Monika Järg, Jüri Kermik, Kerttu Laane, Jaanus Orgusaar, Kristi Paap, Villu Pruulmann, Ruumilabor, Pavel Sidorenko ja Igor Volkov. Ajaloolise disaini osas on väljas Helle Gansi, Maile Grünbergi ning Tarbeklaasi ja Estoplasti tööd

  5. Surve haridusminister Mailis Repsi ametist tagandamiseks kasvab / Kai Kalamees

    Index Scriptorium Estoniae

    Kalamees, Kai

    2005-01-01

    Endine siseminister Ain Seppik nõudis kapolt, et see uuriks haridus- ja teadusminister Mailis Repsi sõnavõtte Marimaal puudutava välisministeeriumi memo jõudmist ajakirjandusse. Opositsioon nõuab ministri tagasiastumist, Toomas Hendrik Ilvese sõnul ei tohi ükski minister lubada endale välismaal oma riigi kritiseerimist

  6. Practical Kunst ja Kodu (Art and Home) / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2009-01-01

    Ajakirjast "Kunst ja Kodu" (1958-1990), mis pakkus eesti sisearhitektide ja tarbekunstnike ideid ja soovitusi kodu planeerimiseks ja sisustamiseks, tekstiilide, mööbli jm. isetegemiseks eesmärgiga tõsta lugejate esteetilist maitset kodukultuuri osas. 5. Tallinna rakenduskunsti triennaali satelliitnäitus "Praktiline Kunst ja Kodu" (kuraator K. Lobjakas) Tallinnas Hobusepea galeriis 14.-23. nov. 2009

  7. J.A.P. Style - killuke rõivailu / Kai Ilustrumm

    Index Scriptorium Estoniae

    Ilustrumm, Kai

    2004-01-01

    Moekunstnike Janina Pasti (õppinud arhitektuuri, sisekujundust, graafikat) ja Aleksandr Pasti (ka ajakirjanik, fotoreporter) firmast J.A.P.Style ja uuest kollektsioonist. Inspiratsiooni saavad Versace loomingust

  8. Šveitsi hommage Mies van der Rohele / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    1999-01-01

    Šveitsi väikelinna Buschi ehitatud voolava ruumilahendusega maja meenutab Mies van der Rohe kujundatud saksa paviljoni maailmanäitusel Barcelonas. Materjalideks betoon, puit, klaas. Loodud on palju erineva kõrgusega pindu maja ja seda ümbritseva müüri vahel. Interjööris punakas tammepuit. Arhitekt: Peter+Christian Frei, Architekten.

  9. Rahandusministeerium : Eestit ootab ees galopeeriv hinnatõus / Kai Kalamees

    Index Scriptorium Estoniae

    Kalamees, Kai

    2007-01-01

    Ilmunud ka: Postimees : na russkom jazõke, 23. aug. 2007, lk. 2. Rahandusministeeriumi prognoosi järgi ootab Eestit 8,1%-line majanduskasv, 2008. aastal 7,4%-line hinnatõus. Rahandusminister Ivari Padari ja üle-eelmise rahandusministri parlamendiliikme Taavi Veskimäe arvamusi palgakasvu, inflatsiooni ja lisaeelarve kohta. Vt. samas: Käes on poliitiliste valikute aeg

  10. Atonen viiks netiühenduse igasse metsatallu / Kai Kalamees

    Index Scriptorium Estoniae

    Kalamees, Kai

    2004-01-01

    Majandus- ja kommunikatsiooniminister Meelis Atonen kavatseb kohtuda Bratsislavas peetaval Kesk- ja Ida-Euroopa riikide IT-ministrite ümarlaual Microsofti juhi Bill Gatesiga, et tekitada temas huvi e-Eesti idee vastu ning teha ettepanek muuta Microsofti ärimudelit nii, et tarkvara hinnad oleksid kodutarbijatele soodsamad ja paindlikumad

  11. Genel Anestezi Altında Çocukta Diş Tedavisi

    OpenAIRE

    Gülhan, A.; Sandallı, N.

    2013-01-01

    ÖZETBu makalede çocuklarda genel anestezi altında diş tedavisinin koşulları anlatıldı ve normal tedavi koşulları sağlanamadığı takdirde, genel anesteziye başvurmanın yararlarına ve sakıncalarına değinildi. Genel anestezi indikasyonları sıralanarak, bunlar arasında en sık rastladığımız «Güç çocuklarım" genci anesteziye başvurmadan Önce hangi yollara başvurularak normal tedavinin deneneceğinden bahsedildi.Bir hastane ortamında genel anestezi altında çalışmaya karar verildikten sonra, bir a...

  12. Ekolojik yüzey işlemlerinin ısırgan ipliğinin fiziksel ve morfolojik özelliklerine etkisinin araştırılması

    OpenAIRE

    Şansal, Seda

    2017-01-01

    Rami, kenaf ve jüt gibi bir sak lifi olan ısırgan lifinin ilk kullanımı çok eskilere dayanmaktadır. Yenilenebilir ve doğal kaynaklı olan ısırgan otu bitkisinin az girdi ile üretilmesi, bu bitkiyi ekolojik açıdan avantajlı hale getirirken, ısırgan otu bitkisinden elde edilen liflerinde çevre dostu lifler arasındaki yerini almasını sağlamaktadır. Bu çalışmada ekolojik yüzey işlemlerinin ısırgan ipliği üzerindeki etkisi asidik ve bazik ortamda araştırılmıştır. Bu kapsamda Giant Himalayan Nettle ...

  13. Tee ajalugu / Maris Takk

    Index Scriptorium Estoniae

    Takk, Maris

    2006-01-01

    Eesti Maanteemuuseumi (Varbuse postijaam, Kanepi vald, Põlvamaa) näitus "Tee ajalugu". Sisekujundus: Krista Lepland, Malle Jürgenson, kaasautor Tea Tammelaan, OÜ Laika, Belka & Strelka. Ehitus: OÜ Bauvel. Postitõlla maalis Kai Kaljo. Eesti Sisearhitektide Liidu 2005. a. näituse kujunduse preemia. T. Tammelaanest, K. Leplandist ja M. Jürgensonist, OÜ Laika, Belka & Strelka tähtsamad tööd. Hedi Rootsist, tema tähtsamad tööd. Ill.: plaan, 28 värv. vaadet, 4 portreefotot

  14. A safety culture assessment by mixed methods at a public maternity and infant hospital in China

    OpenAIRE

    Listyowardojo, Tita Alissa; Yan, Xiaoling; Leyshon, Stephen; Ray-Sannerud, Bobbie; Yu, Xin Yan; Zheng, Kai; Duan, Tao

    2017-01-01

    Tita Alissa Listyowardojo,1 Xiaoling Yan,2,3 Stephen Leyshon,1 Bobbie Ray-Sannerud,1 Xin Yan Yu,4 Kai Zheng,4 Tao Duan2,3 1Life Sciences Program, Group Technology and Research, DNV GL, Hovik, Norway; 2Quality and Safety Department, Shanghai First Maternity and Infant Hospital, 3Tongji University School of Medicine, Shanghai, 4Healthcare Department, Business Assurance, DNV GL, Beijing, China Objective: To assess safety culture at a public maternity hospital in Shanghai, China, using a sequenti...

  15. Kompetisi Industri Transportasi: Tinjauan Komunikasi Pemasaran Jasa PT Kereta Api Indonesia

    Directory of Open Access Journals (Sweden)

    Prima Mulyasari Agustini

    2008-06-01

    Full Text Available The development of transportation industry has removed the train business from its monopolistic business. Sooner or later, the government will open up opportunity for private parties to participate in the train business. In order to successfully anticipate this future, PT Kereta Api Indonesia (KAI needs to change its communication strategy. Integrated Service Marketing Communication (ISMC was recommended as a strategic approach covering management of service promise, management of customer expectation, customer education improvement, and management of internal marketing communication.

  16. On the Epistemology of Narrative Theory : Narratology and Other Theories of Fictional Narrative

    OpenAIRE

    Patron, Sylvie

    2008-01-01

    International audience; This article is made up of two talks presented in French and English, at two conferences : a symposium organized by Matti Hyvärinen and Kai Mikkonen, at Helsinki Collegium for Advanced Studies at the University of Helsinki, and a series of conferences which I organized at Paris 7-Denis Diderot University. The title, which is borrowed from Marc Dominicy's work on Jakobsonian poetics, sets out to analyze narrative theory from an epistemological viewpoint. On the one hand...

  17. Subjektiivselt disainist / Ele Praks

    Index Scriptorium Estoniae

    Praks, Ele

    2007-01-01

    Kuni 8. IV Eesti Tarbekunsti- ja Disainimuuseumis koostöös Briti Nõukoguga avatud näitusest " Minu maailm : uus subjektiivsus kaasaegses disainis", mis koosneb rändnäitusest ja eesti disainerite satelliitnäitusest. Kuraatorid Emily Campell, Andree Cook ja Kai Lobjakas. Annike Laigo, Kärt Ojavee, Krista Leesi, Ülle Jehe, Committee' (Clare Page, Harry Richardson), Danny Browni, Doshi Levieni, Peter Traagi, Wokmedia (Michael Cross, Julie Mathias), Neutrali (Christian Grou, Tapio Snellman) ja Alison Willoughby töödest

  18. The influence of advertising elements on behaviors of consumers

    OpenAIRE

    Valungevičiūte, Sandra

    2014-01-01

    Magistrinio baigiamasis darbas - 67 puslapiai, 11 lentelių, 19 grafikų, 108 literatūros šaltiniai, 3 priedai lietuvių kalba. Tyrimo objektas - reklamos elementai. Tyrimo dalykas - reklamos elementų (teksto,spalvos,garso ir vaizdo) poveikis vartotojų elgsenai. Darbo tikslas – teoriniu lygmeniu išanalizavus ir apibendrinus reklamos elementų įtaką vartotojų elgsenai, juos empiriškai patikrinti Lietuvos studijuojančio jaunimo pavyzdžiu. Darbo uždaviniai: • Atskleisti reklamos sampratą; • Teoriniu...

  19. E-kursuste konkursi tulemused / Reelyka Läheb

    Index Scriptorium Estoniae

    Läheb, Reelyka

    2004-01-01

    01.09.-31.10. 2003 toimus Tallinna Pedagoogikaülikoolis konkurss "Eesti e-Ülikooli toetus e-õppe kursustele, sügis 2003" eesmärgiga töötada välja uusi veebipõhiseid kursuseid. Konkursile laekunud 10 tööst otsustati ellu rakendada kõik. Projekti täitmiseks määrati toetused Hindrek Lootusele, Leif Kalevile, Anu Tootsile, Raivo Vetikule, Tiiu Reimole, Ivar Pornile, Sirje Pihtile, Kai Randrüütile ja Reelyka Lähebile

  20. Integrated marketing communications in theatres’ performance

    OpenAIRE

    Bendinskaitė, Rasa

    2010-01-01

    Šio darbo tikslas atlikus teorines integruotųjų marketingo komunikacijų planavimo teatro veikloje studijas, parengti į teatrą orientuotų integruotųjų marketingo komunikacijų planavimo proceso modelį ir jį patikrinti empiriškai. Atlikus teorines teatro rinkos bei integruotųjų marketingo komunikacijų planavimo proceso studijas, parengtas teorinis planavimo proceso modelis apimantis aštuonis žngsnius: situacijos analizė, tikslinės rinkos nustatymas, komunikacinių tikslų nustatymas, komunikacijų ...

  1. Maintenance of Glucose Homeostasis Through Acetylation of the Metabolic Transcriptional Coactivator PGC1-alpha

    Science.gov (United States)

    2011-02-01

    Salmenniemi, U., Ruotsalainen, E., Pihlajamaki, J., Vauhkonen, I., Kai - nulainen, S., Punnonen, K., Vanninen, E., and Laakso, M. (2004). Mul- tiple...cancer: a dawn for evolutionary medicine. Annu. Rev. Genet. 39, 359–407. Wang, Y.X., Zhang, C.L., Yu , R.T., Cho, H.K., Nelson, M.C., Bayuga- Ocampo...calorie diet, Nature 444 (2006) 337–342. [19] J.M. Wu, Z.R. Wang, T.C. Hsieh , J.L. Bruder, J.G. Zou, Y.Z. Huang, Mechanism of cardioprotection by

  2. Short outlines of books by Estonian authors / Brita Melts, Rutt Hinrikus and Janika Kronberg

    Index Scriptorium Estoniae

    Melts, Brita

    2012-01-01

    Arvustus: Kilusk, Ott. Veidrikud ja võpatused. Tallinn : Menu, 2012 ; Kilusk, Ott. Oktoobrikuine tuuker. Tallinn : Kirjastuskeskus, 2010 ; Hansen, Aime. Ma olin mereingel. Tallinn : Verb, 2011 ; Vallisoo, Mari. Koidutäht koolivihikus. Tartu : Ilmamaa, 2011 ; Sinijärv, Karl Martin. Krümitor 0671. Tallinn ; Näo Kirik, 2011 ; Aareleid, Kai. Vene veri. Tallinn : Varrak, 2011 ; Ashilevi, Jim. Ma olen elus olemise tunne. Luige : Verb, 2011 ; Traat, Mats. Vastsed Harala elulood. Tartu : Ilmamaa, 2011 ; Tamm, Margus. Unesnõiduja. Tallinn : Raudwara, 2011

  3. Onu Miltie mälestuseks ehk Mis seob New Orleansi ja Keilat? / Katrin Saks

    Index Scriptorium Estoniae

    Saks, Katrin, 1956-

    2008-01-01

    16. novembril sai kaks aastat liberaalse majanduse guru Milton Friedmani surmast. Friedmani šokidoktriinist, katastroofikapitalismist ja pimedast usust erakapitali, ajal, mil Keila linnaisad olid otsustanud, et haridust hakkab munitsipaalkooli asemel edendama sihtasutus

  4. Sunnyboy of the North; Sunnyboy im hohen Norden

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2008-07-01

    Parking tickets, handball, North Sea, Baltic Sea: This is what most Germans know about Flensburg. Hardly anyone will associate solar energy in conjunction with this small town on the Danish border. This is an error, as the insolation values of the German coastal regions are quite near those of Freiburg, Germany's number one solar city in the Black Forest. Kai Lippert, director and founder of the EWS company, was aware of this quite early and constructed his PV business in the extreme North. (orig.)

  5. Different Styles for Different Needs – The Effect of Cognitive Styles on Idea Generation

    DEFF Research Database (Denmark)

    Lomberg, Carina; Kollmann, Tobias; Stockmann, Christoph

    2017-01-01

    Researchers are engaged in finding the precursors for innovation. Drawing on Kirton's Adaption-Innovation (KAI) Inventory, we explicitly test Kirton's central premise that cognitive styles differentiate between preferences for producing ideas in a certain way. We argue that the generation of either...... a magnitude or original ideas is governed by different underlying cognitive styles. In a study with 191 individuals, we find that the cognitive style originality associates with ideational fluency whereas the rule governance style associates with the generation of original ideas. By providing a cognitive...

  6. Strateginis paslaugų kokybės viešajame sektoriuje valdymas: Klaipėdos regiono aprūpinimo elektros energija atvejis

    OpenAIRE

    Tamošiūnas, Teodoras; Pečiulytė, Sandra

    2010-01-01

    Tyrimo aktualumas ir problematika. Europos šalyse pastebimas viešojo sektoriaus modernizavimas, pritaikant naujausius, pažangiausius vadybos modelius, tarp jų – ir naujosios viešosios vadybos (Židonis, Rudnickas, 2005). Žvelgiant sistemiškai į šiuo metu keičiamus Lietuvos teisės aktus, matyti, kad viešajame sektoriuje rengiama norminė bazė, kuri gali būti tinkamas teisinis pagrindas įgyvendinant naujus viešojo administravimo principus (Vanagas, 2006). Teorinius strateginio kokybės valdymo asp...

  7. Application of artificial intelligence method in credit risk evaluation

    OpenAIRE

    Danėnas, Paulius

    2008-01-01

    Šis magistrinis darbas aprašo plačiausiai naudojamus dirbtinio intelekto metodus ir galimybes juos taikyti kredito rizikos, kuri yra viena svarbiausių sričių bankininkystėje ir finansuose, vertinime. Pagrindinė problema yra rizikos, atsirandančios kreditoriui išduodant kreditą tam tikram individui ar bendrovei, vertinimas, naudojant įvairius matematinius, statistinius ar kitus metodus. Ši rizika atsiranda tada, kai skolininkas negali laiku grąžinti skolos kreditoriui, kas reiškia papildomus n...

  8. The method for the elimination of double taxation: methods description, meaning, applying in lithuania and in chosen foreign countries

    OpenAIRE

    Juodkaitė, Raimonda

    2007-01-01

    Asmeniui gaunant pajamas keliose valstybėse gali būti susiduriama su dvigubu apmokestinimu. Valstybių praktikoje tarptautinis teisinis dvigubas apmokestinimas atsiranda, kai: a) kelios valstybės tą patį gyventoją laiko savo rezidentu ir apmokestina jo pasaulines pajamas, bei b) pajamų šaltinio valstybė ir rezidavimo valstybė pagal savo vidaus mokesčių įstatymus apmokestina tokias pajamas. Siekiant išvengti dvigubo apmokestinimo valstybės sudaro dvigubo apmokestinimo išvengimo sutartis, kurios...

  9. The relationship of serum HE4, CP2 and HCgp-39 levels with tumor malignancy in patients with endometrial carcinoma

    Directory of Open Access Journals (Sweden)

    Yun-Xia Rao

    2017-04-01

    Full Text Available Objective: To study the relationship of serum human epididymis protein (HE4, cancer protein-2 (CP2 and human cartilage glycoprotein-39 (HCgp-39 levels with tumor malignancy in patients with endometrial carcinoma. Methods: A total of 90 patients with endometrial carcinoma treated in our hospital between May 2012 and August 2015 were collected and divided into early-to-mid (Ⅰ-Ⅲ stage endometrial carcinoma group (n=59 and advanced (Ⅳ stage endometrial carcinoma group (n=31 according to the pathological staging, and 34 patients with endometrial thickening who received uterine curettage in our hospital during the same period were selected as control group. The levels of HE4, CP2, HCgp-39 and tumor markers in serum as well as the mRNA expression of proliferation genes and invasion genes in tumor tissue were determined. Results: HE4, CP2, HCgp-39, CA125, CA19-9 and CEA levels in serum as well as Bcl2, Chk1, PIK1, HER2 and GDF-15 mRNA expression in tumor tissues of early-to-mid endometrial carcinoma group and advanced endometrial carcinoma group were significantly higher than those of control group while the miRNA-199a-3p, Bax, caspase3, BRCA1, Kiss-1 and KAI1 mRNA expression were lower than those of control group; HE4, CP2, HCgp-39, CA125, CA19-9 and CEA levels in serum as well as Bcl2, Chk1, PIK1, HER2 and GDF-15 mRNA expression in tumor tissues of advanced endometrial carcinoma group were significantly higher than those of early-to-mid endometrial carcinoma group while the miRNA-199a-3p, Bax, caspase3, BRCA1, Kiss-1 and KAI1 mRNA expression were lower than those of early-to-mid endometrial carcinoma group; serum HE4, CP2 and HCgp-39 levels were positively correlated with CA125, CA19-9, CEA, Bcl2, Chk1, PIK1, HER2 and GDF- 15, and negatively correlated with miRNA-199a-3p, Bax, caspase3, BRCA1, Kiss-1 and KAI1. Conclusion: Serum HE4, CP2 and HCgp-39 levels can directly reflect the tumor malignancy in patients with endometrial carcinoma, and are

  10. Toward a model of employee engagement in a public service organization

    DEFF Research Database (Denmark)

    Nielsen, Mette Strange

    Employee engagement has long been capturing the attention of researchers and practitioners, (e.g. Bakker, Albrecht, & Leiter, 2011; Buckingham & Coffman, 1999) due to its positive impact on various measures of organizational performance (Gruman & Saks, 2011; Harter, Schmidt, & Hayes, 2002; Mone...... & London, 2010). To date, however, employee engagement has primarily been studied in private manufacturing firms leaving out a gap of research in a public service organization, such as eldercare organizations, although engagement according to Boselie (2010) is highly relevant in the specific context....... The purpose of the PhD project is to build a model explaining employee engagement in a public service organization. Research on work design theory (e.g. Hackman & Oldham, 1976) will be used, since it has often been applied to identify antecedents associated with engagement (Bakker & Demerouti, 2007; Kahn...

  11. Cloud Computing: Virtual Clusters, Data Security, and Disaster Recovery

    Science.gov (United States)

    Hwang, Kai

    Dr. Kai Hwang is a Professor of Electrical Engineering and Computer Science and Director of Internet and Cloud Computing Lab at the Univ. of Southern California (USC). He received the Ph.D. in Electrical Engineering and Computer Science from the Univ. of California, Berkeley. Prior to joining USC, he has taught at Purdue Univ. for many years. He has also served as a visiting Chair Professor at Minnesota, Hong Kong Univ., Zhejiang Univ., and Tsinghua Univ. He has published 8 books and over 210 scientific papers in computer science/engineering.

  12. Salicilo rūgšties įtaka kvapiojo baziliko ir vaistinio čiobrelio atsparumui sausrai atšilusio klimato sąlygomis

    OpenAIRE

    Vaitkevičiūtė, Birutė

    2018-01-01

    Pastaraisiais metais vis labiau ir labiau tampa aktualūs pasauliniai klimato pokyčiai. Taigi, svarbu nustatyti ir aptarti kaip šie veiksniai veikia vaistinių augalų fiziologinius, morfometrinius ir biocheminius rodiklius. Yra atlikta daug tyrimų kaip klimato kaita veikia kultūrinius augalus, maisto kokybę ir piktžoles. Tačiau beveik nėra tyrimų kaip salicilo rūgštimi (SR) veikti augalai reaguoja į atšilusio klimato ir sausros sąlygas. Augalai buvo auginami automatiškai kontroliuojamomis dabar...

  13. Smulkaus ir vidutinio verslo konkurencingumas Lietuvoje

    OpenAIRE

    Vijeikis, Juozas; Makštutis, Antanas

    2009-01-01

    Straipsnio mokslinė problema, naujumas ir aktualumas. Konkurencingumas kaip įmonių efektyvios veiklos reiškinys yra aktualus šalies verslo gyvenime vykdant darnios ekonominės plėtros politiką. Ši politika kaip problema smulkaus ir vidutinio verslo (SVV) plėtrai ir konkurencingumui didinti nėra sistemiškai ištirta ir aprašyta Lietuvos sąlygomis mokslinėje ir praktinėje literatūroje. Vienas svarbiausių veiksnių, siekiant spartaus ekonominio augimo, yra darnios verslininkystės plėtra Lietuvoje n...

  14. Mokytojų subjektyvaus sveikatos vertinimo, socialinės kompetencijos ir mokyklos baimės sąsajos

    OpenAIRE

    Mokusienė, Rima

    2009-01-01

    Tyrime dalyvavo 132 Akmenės rajono mokytojai. (94 gimnazijos mokytojai, 14 pagrindinės mokyklos mokytojų, 16 specialiosios mokyklos mokytojų, 8 muzikos mokyklos mokytojai) Visi tiriamieji - moterys, įgiję aukštąjį išsilavinimą. Tyrimo metodai - metodika socialinei kompetencijai tirti, sudaryta iš 45 teiginių (R. Ullrich ir de R. Muynck Socialinės kompetencijos testas (Vokietija, 1994) adaptavo R.Lekavičienė, 2000). Mokytojų baimės dažnumui ir raiškai nustatyti, naudotas R.Kreitschmann, B.Weid...

  15. Analysis of young people expectations in Lithuanian labour market

    OpenAIRE

    Bakanauskienė, Irena; Brazaitytė, Greta

    2014-01-01

    Straipsnyje pateikiami rezultatai tyrimo, siekiančio nustatyti jaunų žmonių, potencialių darbo rinkos dalyvių, poreikius bei juos lemiančius veiksnius Lietuvoje. Straipsnyje metodologiškai pagrindžiamos pagrindinės teorinės nuostatos ir tyrimo metodologija. Taip pat analizuojami gauti tyrimo rezultatai, kurie, pasitelkiant A. Maslow teorijos poreikių grupes ir juos lemiančius veiksnius, atskleidžia jaunų žmonių lūkesčius Lietuvos darbo rinkoje; pateikiamas šių poreikių rangavimas pagal svarbą...

  16. PENGARUH STRATEGI BELAJAR PETA KONSEP TERHADAP KETUNTASAN BELAJAR MATEMATIKA SISWA

    Directory of Open Access Journals (Sweden)

    Ika Eryanti

    2015-12-01

    random sampling. Tes yang diberikan sebanyak 10 soal berbentuk uraian. Uji prasyarat analisis dalam penelitian ini menggunakan Uji Kai Kuadrat (chi square, Uji Fisher dan teknik analisis data menggunakan Uji-t. Berdasarkan hasil perhitungan pengujian hipotesis diperoleh thitung=2,11, pada taraf signifikansi 5% dan db=76, diperoleh ttabel=1,99. Karena thitung> ttabel (2,11>1,99, maka Ho ditolak, artinya skor rata-rata tes akhir siswa kelompok eksperimen yang dalam pembelajarannya menggunakan strategi belajar peta konsep lebih tinggi dari pada skor rata-rata tes akhir siswa kelompok kontrol yang menggunakan pembelajaran konvensional.

  17. Oskusteabe tarbekunsti-tiritamm / Lylian Meister

    Index Scriptorium Estoniae

    Meister, Lylian, 1966-

    2009-01-01

    Tallinna 5. rakenduskunsti triennaalist. Peanäitus "Know how" Eesti Tarbekunsti- ja Disainimuuseumis kuni 21. 02. 2010 (kuraator Kärt Maran, kujundajad: Ott Kadarik, Tuuli Aule). Kolm võrdset preemiat said Marta Boan (Hispaania), autorite kollektiiv Jaan Evart (Eesti), Julian Hagen (Austria) ja Daniel Maarleveld (Holland) ning Kieren Jones (Suurbritannia). Satelliitnäitused: "EKA Know How. See on imelihtne?" (kuraatorid: Eeva Käsper, Tiina Sarapu) Eesti Kunstiakadeemia galeriis 12. 11.-10. 12. 2009, "Praktiline Kunst ja Kodu" (kuraator Kai Lobjakas, kujundaja Mikk Heinsoo) Hobusepea galeriis 14.-23. 11. 2009

  18. 15 tähtteost Eesti kunsti 15 aastast / Harry Liivrand

    Index Scriptorium Estoniae

    Liivrand, Harry, 1961-

    2006-01-01

    Kunstiteosed, mis on märgilise tähendusega nii nende loojate loomingus kui eesti kunstiajaloo kontekstis: Raoul Kurvitz "Ararat", Jaan Toomik "...16. mai-31. mai 1992", Jüri Ojaver "Nišš. Image", Raul Rajangu "Playboy House", Jaan Toomik "Tantsides koju", Ado Lill "Nimetu 55", Kai Kaljo "Luuser", Mark Raidpere sari "Io", Ene-Liis Semper "FF/Rew", Laurentsius & AD "Roos XXII", Mare Tralla "Sing with me!", Peeter Allik"Ma nägin seda", Kaido Ole "Tüdruk ja poiss", Jaan Elken "Video Kills a Radio Star", Andres Tali "Pastoraalne pastishsh"

  19. Objektinis programavimas ir vartotojo grafinis interfeisas (GUI) NetBeans aplinkoje

    OpenAIRE

    Jasiulionis, Rolandas

    2008-01-01

    Darbe nagrinėjami objektinio programavimo principai. Apžvelgiama Java programavimo kalba, jos platformos, virtualioji mašina, programų tipai. Apžvelgiami Java baziniai paketai, klasės. Aprašyta programavimo aplinka ir vartotojo grafinės sąsajos (interfeiso) kūrimas NetBeans aplinkoje. Aprašyti pagrindiniai swing ir awt paketų komponentai. Programiškai realizuoti ir aprašyti keli uždaviniai NetBeans aplinkoje, kurie demonstruoja vartotojo grafinės sąsajos kūrimą. Darbo tikslas yra NetBeans apl...

  20. SEB VB Investicijų valdymas valdomų ir platinamų investicinių fondų portfelio optimizavimas

    OpenAIRE

    Kurlianskaitė, Rimantė; Stonienė, Lina

    2007-01-01

    Magistro darbe plačiai nagrinėjami H. Markowitz (1952), J. Tobin (1958), W. Sharpe (1964), S. Ross (1976), G. Fama ir K. French (1993) ir kitų autorių darbai, kuriuose akcentuojami portfelio formavimo kriterijai bei optimalaus portfelio sudarymo problemos. Darbas apima modernios portfelio teorijos praktinio pritaikymo aspektus, įvertinant vertybinių popierių atrankos į portfelį ir jų įkainojimo ypatumus bei portfelio vertę įtakojančius veiksnius, ieškant būdų jiems kiekybiškai išreikšti. Atli...

  1. Judicial Peculiarities of the Collective Labour Disputes Resolution: International Regulation, Experience of Foreign Countries and Future Perspectives in Lithuania

    OpenAIRE

    Bumblauskytė, Simona

    2007-01-01

    Šiame darbe yra pateikiama vienos darbo ginčų rūšies, tai yra kolektyvinių darbo ginčų, teisminio nagrinėjimo tarptautinio reglamentavimo ypatumai ir kai kurių užsienio valstybių patirties analizė bei šio metodo naudojimo Lietuvoje perspektyvos. Teisminis kolektyvinių darbo ginčų nagrinėjimas yra jau seniai žinomas, efektyviai taikomas ir teigiamai vertinamas daugelyje užsienio valstybių, o tuo tarpu Lietuvos Respublikos teisės aktuose teisminis kolektyvinių darbo ginčų nagrinėjimas tiesiogia...

  2. „X“ banko darbuotojų socializacijos organizacijoje tyrimas

    OpenAIRE

    Guzevičienė, Julija

    2013-01-01

    Magistro baigiamajame darbe išanalizuotas naujų darbuotojų socializacijos procesas, įvertinti konkrečios stambios finansinės institucijos naujų darbuotojų socializacijos trūkumai bei privalumai, pateikiamos išvados bei siūlymai organizacijai. Darbe iškelta problema – dažna darbuotojų kaita Lietuvos organizacijose, kuriai turi įtakos prasta naujų darbuotojų socializacija bei nepakankamas dėmesys šiam procesui, kuris privalo būti sistemiškai nukreiptas į visapusišką darbuotojų įsiliejimą į gamy...

  3. Effects of Mothers’ Attitude as Breeders and Distance of Stockyard toward Diarrhea Incidence among Toddlers

    Directory of Open Access Journals (Sweden)

    Yarmaliza - Yarmaliza

    2016-02-01

    hubungan sikap ibu sebagai peternak dan jarak kandang ternak terhadap kejadian diare pada balita di wilayah kerja Puskesmas Kecamatan Meureubo. Penelitian ini dilakukan secara potong lintang pada bulan Juli – September 2015. Sampel sebanyak 70 ibu yang memiliki balita dengan gejala diare. Analisis data menggunakan univariat, bivariat dan multivariat. Uji kai kuadrat menunjukkan bahwa sikap ibu sebagai peternak dan jarak kandang ternak berhubungan dengan kejadian diare pada balita (nilai p 0,05. Kejadian diare pada balita berhubungan dengan sikap ibu sebagai peternak dan jarak kandang ternak, namun hubungannya tidak kuat.

  4. Lusikas tõi Riho Tiivelile disainikonkursilt võidu / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2005-01-01

    Eesti Kunstiakadeemia disainitudeng Riho Tiivel võitis Itaalia disainivõistluse "ReAL13 - Eating Anywhere" peapreemia ühekordselt kasutatava lusikaga "Spoon Container". Võidutöö ideest. Lühiintervjuu autoriga

  5. Käsitsi tegemise võlu / David Jones ; intervjueerinud Kai Lobjakas

    Index Scriptorium Estoniae

    Jones, David, 1953-

    2010-01-01

    10. Kohila keraamikasümpoosionil osalenud briti keraamik ja teoreetik David Jones endast, rakutehnikast, huvist põletamisega seonduvate teemade vastu, Kohila sümpoosioni raames tehtust, keraamika õpetamisest Inglismaal, käsitöö ja keraamika positsioonist praegu ja tulevikus jm.

  6. Ilmunud on raamatukogude mõju hindamise standard / Kai Välbe

    Index Scriptorium Estoniae

    Välbe, Kai

    2016-01-01

    Raamatututvustus: Informatsioon ja dokumentatsioon [Võrguteavik] : raamatukogude mõju hindamise meetodid ja menetlused / tõlkinud Sirje Nilbe. Tallinn : Eesti Standardikeskus, 2016. (Eesti Standard ; EVS-ISO 16439:2016)

  7. Mechanisms of KAI1/CD82-Induced Prostate Cancer Metastasis

    Science.gov (United States)

    2011-08-01

    survival signaling is also compromised by BRMS1-mediated ors, KiSS and TNXIP. TNXIP limits survival via inhibition of the redox protein Trx , but also...that regulates the expression of two other metastasis suppressors, KiSS and TNXIP. TNXIP/VDUP1 binds the redox-active site of thioredoxin ( Trx ) to...negatively regulate its activity [225]. The Trx system, like the GSH system, acts to reduce intracellular ROS. Trx associates with ASK1, a stress

  8. Käsitöötund ja õpilaste loovus / Kai Malmstein

    Index Scriptorium Estoniae

    Malmstein, Kai

    2001-01-01

    TPÜ käsitöö ja kodunduse eriala diplomand Lemme Kurvits viis 2000.a. läbi uuringu, et selgitada õpilaste arvamust oma loovatest võimetest ja suhtumist käsitöötundidesse. Küsimustele vastas 250 8.-9. klassi õpilast kaheksast koolist ning nende koolide käsitööõpetajad

  9. Legalizatsija elektroshokerov võzõvajet protestõ deputatov / Kai Kalamees

    Index Scriptorium Estoniae

    Kalamees, Kai

    2008-01-01

    Vaidlustest elektrishokirelva kasutamise ja politseile eriõiguste andmise üle. Lisatud Aadu Musta ja Jüri Pihli arvamus väljavõttena riigikogus 16. märtsil peetud debatist jalaraudade kasutamise üle

  10. Tallinn andis õpilastele preemia alkovaba noortejoogi leiutamise eest / Kai Maran

    Index Scriptorium Estoniae

    Maran, Kai

    2014-01-01

    Ettevõtluskonkursi ENTRUM raames sai Tallinna linna eripreemia "Parim Tallinna Start-up 2014" Tallinna Vanalinna Hariduskolleegiumi ja Estonian Business School'i koolinoorte start-up Passion Group idee eest toota tervisliku ja alkoholivaba mahlajookide seeria

  11. Triennaalist ja preemiatest : tarbekunst / Lesley Jackson ; tõlk. Kai Lobjakas

    Index Scriptorium Estoniae

    Jackson, Lesley

    2006-01-01

    Inglise disainiajaloolane, auhinnažürii liige Eesti Tarbekunsti- ja Disainimuuseumis avatud IV Tallinna rakenduskunsti triennaalist "Kaks lähedast" ja preemia saanud töödest. Näituse kujundus: 3+1 Arhitektid. I preemia: Kersti Laanmaa ja Tiit Rammuli (rühmitus Muki) töö "Loomaarmastus", kaks teist preemiat: Piret Valk "Maa vägi", Caro Bärtling "Salvrätt-kraed"

  12. Kognitiivsete ja metakognitiivsete õpistrateegiate toetamine tehnoloogiaga tõhustatud keeleõppes / Katrin Saks, Äli Leijen

    Index Scriptorium Estoniae

    Saks, Katrin, 1968-

    2015-01-01

    Tehnoloogiliste vahenditega tõhustatud võõrkeelekursuse raames välja töötatud sekkumisest, mis võimaldab õpetajal parimal moel toetada õppijate kognitiivseid ja metakognitiivseid keele- õppestrateegiaid

  13. Orlicz difference sequence spaces generated by infinite matrices and de la Vallée-Poussin mean of order α

    Directory of Open Access Journals (Sweden)

    Bipan Hazarika

    2016-10-01

    Full Text Available In this paper we introduce the spaces V^λ[A,M,Δ,p]o,V^λ[A,M,Δ,p] and V^λ[A,M,Δ,p]∞ generated by infinite matrices defined by Orlicz functions. Also we introduce the concept of S^λ[A,Δ]−convergence and derive some results between the spaces S^λ[A,Δ] and V^λ[A,Δ]. Further, we study some geometrical properties such as order continuity, the Fatou property and the Banach–Saks property of the new space V^λα[A,Δ,p]∞. Finally, we introduce the notion of almost λ-statistically-[A, Δ]-convergence of order α or S^λα[A,Δ]−convergence and obtain some inclusion relations between the set S^λα[A,Δ] and the space V^λα[A,Δ,p]∞.

  14. Prūsų kalbos pirminių vardažodžių morfemų akcentinė galia

    Directory of Open Access Journals (Sweden)

    Vytautas Rinkevičius

    2011-12-01

    Full Text Available THE ACCENTUAL POWER OF OLD PRUSSIAN PRIMARY NOMINAL MORPHEMESSummaryThe article presents the first attempt to describe the Old Prussian accentuation system based on the main principles of morphological accentology. It aims to distinguish accentual properties of morphemes that determine the placement of stress in primary (non-derived Old Prussian nouns. At least one accentual property of morphemes (roots and inflexions, i.e. accentual power (strong vs. weak, could be distinguished. Strong root morphemes are roots that remain stressed in all forms of a paradigm, while the weak ones are those that lack stress in at least one form. Thus nouns with strong roots (eg. grīkai, kaulei, crixtiānimans, rūkai, wijrai (wijrimans; kīrki, kurpi, mūti, rīki, tapali; most probably also uremmans, wirdemmans; also possibly kaāubri, strigli belong to the constant stem-stress class, while nouns with weak roots (eg. gallū, gennāmans, mensā, mergūmans, widdewū; semmē; also possibly waikammans, kermenes belong to the mobile stress class. Strong inflexional morphemes are those that are stressed in position after weak roots (eg. nom. sg. fem. -ā (-ū, -ē; nom. pl. masc. ai; dat. pl. -āmans (-ūmans, -amans, while the weak ones are never stressed (eg. acc. sg. -an, -in; -ans, -ins; also possibly nom. pl. of ā-, ē-, i-, u-stems, acc. pl. and dat. sg. of all flexional types and gen. sg. of ā-stem.

  15. Plant growth-promoting activities of Streptomyces spp. in sorghum and rice.

    Science.gov (United States)

    Gopalakrishnan, Subramaniam; Srinivas, Vadlamudi; Sree Vidya, Meesala; Rathore, Abhishek

    2013-01-01

    Five strains of Streptomyces (CAI-24, CAI-121, CAI-127, KAI-32 and KAI-90) were earlier reported by us as biological control agents against Fusarium wilt of chickpea caused by Fusarium oxysporum f. sp. ciceri (FOC). In the present study, the Streptomyces were characterized for enzymatic activities, physiological traits and further evaluated in greenhouse and field for their plant growth promotion (PGP) of sorghum and rice. All the Streptomyces produced lipase, β-1-3-glucanase and chitinase (except CAI-121 and CAI-127), grew in NaCl concentrations of up to 6%, at pH values between 5 and 13 and temperatures between 20 and 40°C and were highly sensitive to Thiram, Benlate, Captan, Benomyl and Radonil at field application level. When the Streptomyces were evaluated in the greenhouse on sorghum all the isolates significantly enhanced all the agronomic traits over the control. In the field, on rice, the Streptomyces significantly enhanced stover yield (up to 25%; except CAI-24), grain yield (up to 10%), total dry matter (up to 18%; except CAI-24) and root length, volume and dry weight (up to 15%, 36% and 55%, respectively, except CAI-24) over the control. In the rhizosphere soil, the Streptomyces significantly enhanced microbial biomass carbon (except CAI-24), nitrogen, dehydrogenase (except CAI-24), total N, available P and organic carbon (up to 41%, 52%, 75%, 122%, 53% and 13%, respectively) over the control. This study demonstrates that the selected Streptomyces which were antagonistic to FOC also have PGP properties.

  16. Broilerienos paklausa ir pasiūla Lietuvoje

    OpenAIRE

    Paškauskienė, Kristina

    2008-01-01

    Labai svarbu ir savalaikiškai ištirti vartotojų poreikį broilerienai, aktualu nustatyti vartotojų požiūrį į Lietuvoje užauginamą produkciją bei importuotą. ir kokia yra priklausomybė vyrų bei moterų tarpe, ir nuo gaunamo atlyginimo. Vartotojų tyrimai rodo, kad auga paklausa lengvai virškinamiems, greitai paruošiamiems, aukštos maistinės kokybės gyvulininkystės produktams. Darbo tikslas - Išsiaiškinti broilerienos paklausą ir pasiūlą Lietuvoje, įvertinti broilerienos suvartojimo tendencija...

  17. Evaluations parameter of pedagogical prevention of risky adolescent sexual behaviour

    OpenAIRE

    Obelenienė, Birutė

    2008-01-01

    Šiandieninę situaciją švietimo sistemoje lytiškumo ir jaunimo rengimo šeimai srityje galima vadinti prieštaringa tarp deklaruojamų švietimo sistemos ugdymo tikslų ir taikomų pedagogiškai nepagrįstų rizikingos lytinės elgsenos prevencijos metodų bei priemonių. Iš tiesų taip yra sutapatinamos dvi skirtingos veiklos rūšys, turinčios skirtingus tikslus: 1) pedagoginė prevencija – lytinis ugdymas ir lytiškumo ugdymas, kuris yra nukreiptas į ankstyvuosius lytinius santykius sąlygojančius rizikos ir...

  18. Internationality meets locality - ART IST KUKU NU UT festival in Tartu / Tanel Rander

    Index Scriptorium Estoniae

    Rander, Tanel, 1980-

    2012-01-01

    Kunstifestivalist ART IST KUKU NU UT. Näitusest "Möh? Fui! Öäk! Ossa! Vau! Eesti kaasaegse kunsti klassika" (06.09.-18.11.2012) Tartu Kunstimuuseumis. Festivali projektijuht Kaisa Eiche, kunstiline juht ja näituse kuraator Rael Artel. Näitusel osalesid Jaan Toomik, Raul Meel, Kai Kaljo, Johnson & Johnson, Anna-Stina Treumund ja Flo Kasearu. Chris Fitzpatrick'u kureeritud näitusest "Sõida tasa üle silla" (07.-30.09.2012) galeriis Noorus. Kuku Nunnu stipendiaadi Eike Epliku isikunäitusest "Tüdruk, kes kõike arnastas" (07.09.-28.10.2012) Y-galeriis

  19. Arhitektuurikonkursid 2004

    Index Scriptorium Estoniae

    2004-01-01

    Tulemused: Pärnu kergejõustikumaneezh: I preemia - Ralf Lõoke ja Karli Luik; Tartus Raatuse, Pika, Fortuuna ja Põigu tänava vahelise ala hoonestuskava: I - Kai Kuusik ja Taavi Kuri; Aasta betoonehitis 2003: peapreemia - Emil Urbel; Veneetsia IX rahvusvahelise arhitektuuribiennaali "Metamorfoosid" raames eksponeeritava eesti kaasaegse arhitektuuri näituse ideekonkurss: I - Kristjan Holm; äri- ja elumaja Pärnus Aida t. 5: I - Andres Lember; Eesti parim puitehitis 2003-2004: I - Aivo Schults; Eesti parim tellishoone 2003-2004: I- Tiit Trummal; Sõmeru keskusehoone: I - Ralf Lõoke ja Maarja Kask; Eesti Maanteemuuseumi välialade maastikuarhitektuurne ideekonkurss: I - Margit Kärner

  20. Kovos peilių kilmės vidurio Lietuvoje klausimas

    OpenAIRE

    Bertašius, Mindaugas

    2007-01-01

    Kovos peilių kilmės klausimas lietuviškoje archeologinėje literatūroje buvo aptarinėjamas epizodiškai. Apibūdinant kovos peilius gana dažnai argumentuojama formaliais kriterijais (pvz., kovos peilis, jei ginklo ilgis viršija 20 cm, ar pan.), pamirštant, kad priešistoriniais laikais tokia matų sistema neegzistavo. Ieškant atsakymo pasitelkta gausi Marvelės kapinyno medžiaga (kapinynas yra Kauno miesto teritorijoje). Aiškėja, kad svarbiomis charakteristikomis tampa ginklo funkcinės ypatybės bei...

  1. History of Academic Neurology in Latvia / Akadēmiskās Neiroloģijas Vēsture Latvijā

    Directory of Open Access Journals (Sweden)

    Balta Anita

    2015-09-01

    Full Text Available Raksts sniedz īsu ieskatu akadēmiskās neiroloģijas attīstībā Latvijā dažādos laika periodos, sākot no tās pirmsākumiem neilgi pēc Latvijas Republikas dibināšanas, līdz pat šim brīdim, kā arī par izcilākajām personībām neiroloģijā, kuru devums attiecīgajā zinātnes jomā ir bijis visievērojamākais.

  2. Kutsealase väljaõppega tegelev AEL Eestis / Leila Pärtelpoeg

    Index Scriptorium Estoniae

    Pärtelpoeg, Leila, 1927-

    1998-01-01

    Soome Ammatti Edistys Liitto (AEL) korraldas 1995.-1998. a. Tartu Kunstikooli juures kunsti- ja ehituskoolide õpetajatele restaureerimisalase koolituse, mille viisid läbi Maija-Liisa Hirvi, Leena Hakli, Juta Jokinen. Kursusest, praktikast 1996-1998. Marmoreerimiseks valiti Palmse supelmaja (ehitatud 1980, projekt Aarne Kann). Vinjetid kuppelsaali eesruumidesse maalis Eve Erman. Kohvik avati 1998. a. mais. Illusoorsete seinamaalingute loomisest Järlepa mõisa 1997. a., teema valikust lähtuvalt Järlepaga seotud A. J. von Krusensternist. Gravüüride valik - Kai Tuvik. Objektide sisearhitekt Leila Pärtelpoeg. Käsitsimaalitud tapeedid valmistatakse Järlepa Hiina salongi augustis 1998

  3. Excise duty according to es law and the practise of european court of justice

    OpenAIRE

    Motuzaitė, Inga

    2009-01-01

    Europos Sąjungoje bendra akcizų sistema yra pakankamai nauja, todėl ši sritis nėra plačiai išnagrinėta – praktiškai nėra literatūros nei lietuvių, nei užsienio kalbomis. Ši tema yra pakankamai aktuali, kadangi akcizų mokesčiai yra svarbus valstybių pajamų surinkimo šaltinis ir harmonizavimas Europs Sąjungos lygiu veikia ne tik vidaus rinką, bet ir atskirų valstybių narių ekonomiką, biudžetą. Akcizas yra netiesioginis vartojimo mokestis, kuriuo apmokestinami specifiniai produktai (alkoholis, a...

  4. Improving social marketing mix in non-profit organizations

    OpenAIRE

    Bilvinaitė, Arūnė

    2014-01-01

    Socialinio marketingo sąvoka dažniausiai yra siejama su ne pelno siekiančiomis organizacijomis. Marketingo principai tradiciškai naudojami pateikiant prekes ar paslaugas vartotojams. Tačiau pastaruoju metu jie vis dažniau taikomi, siekiant pagelbėti žmonėms ir aplinkai, veikti tiek atskirų asmenų ar jų grupių bei visos visuomenės elgseną dėl tam tikrų priežasčių, siekiant tam tikro rezultato. Toks marketingo naudojimas sąlygojo socialinio marketingo koncepcijos atsiradimą. Darbo objektas- soc...

  5. Neariminio žemės dirbimo poveikis vasarinių rapsų agroekosistemos komponentams

    OpenAIRE

    Petrauskas, Tomas

    2014-01-01

    Tikslas – įvertinti tiesioginės sėjos, supaprastinto žemės dirbimo ir augalinių liekanų įtaką kai kuriems vasarinių rapsų agroekosistemos komponentams. Stacionarus dviejų veiksnių lauko eksperimentas įrengtas 1999 m. Aleksandro Stulginskio universiteto Bandymų stotyje. A veiksnys − šiaudų panaudojimas: šiaudai pašalinti (-Š); šiaudai susmulkinti ir paskleisti (+Š). B veiksnys − žemės dirbimos sistemos: įprastas gilus arimas 23–25 cm gyliu rudenį (GA), kontrolinis variantas; seklus arimas 10–1...

  6. SQL užklausų rašymo gebėjimų vertinimo sistema

    OpenAIRE

    Ruzgys, Mindaugas

    2014-01-01

    Faktiškai kiekviena šiuolaikinė IS naudoja duomenų bazes, kad saugoti informaciją. Šiuo metu populiariausios reliacinės duomenų bazių valdymo sistemos, kur užklausos rašomos SQL kalba. Todėl kiekvienas programuotojas privalo gebėti rašyti SQL užklausas Rinkoje labai mažai sistemų, skirtų MySQL žinių testavimui, kurios atitinka visus keliamus reikalavimus ir yra nemokamos. Most of bigger web solutions use databases for data storage.This is why all programmers must be familiar with SQL and i...

  7. Practicing Kokugo

    DEFF Research Database (Denmark)

    Hansen, Annette Skovsted

    2014-01-01

    on the periphery of nation and empire, this essay analyzes concrete recommendations made by classroom teachers. I argue that teachers trained at the new normal schools authored articles for the journals of the Teikoku kyoiku kai (Imperial Education Society) that fundamentally changed the central discourse......Professionally trained teachers shifted an ideological debate to a discussion of how to increase their students' potential to navigate within new power structures of the Japanese nation and empire. While other scholars have described how many teachers opposed the idea of kokugo not least...... on kokugo by introducing theoretical and pedagogical considerations tested and inspired by classroom experiences....

  8. Qademah Fault 3D Survey

    KAUST Repository

    Hanafy, Sherif M.

    2014-01-01

    Objective: Collect 3D seismic data at Qademah Fault location to 1. 3D traveltime tomography 2. 3D surface wave migration 3. 3D phase velocity 4. Possible reflection processing Acquisition Date: 26 – 28 September 2014 Acquisition Team: Sherif, Kai, Mrinal, Bowen, Ahmed Acquisition Layout: We used 288 receiver arranged in 12 parallel lines, each line has 24 receiver. Inline offset is 5 m and crossline offset is 10 m. One shot is fired at each receiver location. We use the 40 kgm weight drop as seismic source, with 8 to 15 stacks at each shot location.

  9. Does the requirement to personally participate in the covenant of marriage contradicts the principle of contractual freedom?

    OpenAIRE

    Vonžodaitė, Ramunė

    2017-01-01

    Šiame darbe nagrinėjamas sutarties laisvės principo ir santuokos sudarymo procedūros santykis. Keliamas klausimas ar reikalavimas sudaryti santuoką abiems sutuoktiniams asmeniškai dalyvaujant nepažeidžia minėto principo. Siekiama išsiaiškinti ar sutuoktiniams valstybė užtikrina teisę pasirinkti santuokos sudarymo procedūrą. Darbe taipogi apžvelgiama šeimos ir santuokos sampratų kaita ir priežastys, kodėl šios sampratos kinta. Šeimos samprata aiškinama kaip teisinė ir kaip socialinė kategorij...

  10. Lyties įtaka pratimų sukeltai raumens pažaidai ir atsigavimui

    OpenAIRE

    Inokaitis, Hermanas

    2008-01-01

    Vieningos nuomonės dėl hormonų įtakos raumenų nuovargiui ir atsigavimui nėra. Kai kuriuose literatūros šaltiniuose teigiama, kad moterims nuovargis pasireiškia vėliau nei vyrams, kitose, jog skirtumo tarp lyčių nėra (Clark, 1986; Hunter & Enoka, 2001; Clark et al., 2003). Vienose mokslinėse publikacijose teigiama, kad moterų kreatinkinazės aktyvumas po ekscentrinio fizinio krūvio buvo mažesnis nei vyrų (Staron et al., 1992). Kituose mokslo darbuose nurodoma, kad atliktų tyrimų duomenimis, kre...

  11. Klp10A modulates the localization of centriole-associated proteins during Drosophila male gametogenesis.

    Science.gov (United States)

    Gottardo, Marco; Callaini, Giuliano; Riparbelli, Maria Giovanna

    2016-12-16

    Mutations in Klp10A, a microtubule-depolymerising Kinesin-13, lead to overly long centrioles in Drosophila male germ cells. We demonstrated that the loss of Klp10A modifies the distribution of typical proteins involved in centriole assembly and function. In the absence of Klp10A the distribution of Drosophila pericentrin-like protein (Dplp), Sas-4 and Sak/Plk4 that are restricted in control testes to the proximal end of the centriole increase along the centriole length. Remarkably, the cartwheel is lacking or it appears abnormal in mutant centrioles, suggesting that this structure may spatially delimit protein localization. Moreover, the parent centrioles that in control cells have the same dimensions grow at different rates in mutant testes with the mother centrioles longer than the daughters. Daughter centrioles have often an ectopic position with respect to the proximal end of the mothers and failed to recruit Dplp.

  12. Projekts Sporta kluba izveidošanai

    OpenAIRE

    Andrejevs, Jurijs

    2010-01-01

    Maģistra darba temats ir „PROJEKTS SPORTA KLUBA „URBAN GYM” IZVEIDOŠANA.” Uzņēmējdarbības vide Latvijā pēdējos gados sākusi stipri vien mainīties. No vienas puses, tā lēnām kļūst sakārtotāka, no otras puses, iezīmējas arvien lielāks konkurences pieaugums. Tirgus tiek piesātināts, un aizvien grūtāk kļūst darboties, nedomājot par konkurenci, darbības aktivitāti un rentabilitāti. Vadītājiem un īpašniekiem nemitīgi jādomā, ar ko uzņēmums īsti pelna naudu, kā varētu pelnīt vairāk. Bet neskatoti...

  13. Tuleva aasta riigielarve kavas laiutab 300 miljoni kroonine auk / Kai Kalamees

    Index Scriptorium Estoniae

    Kalamees, Kai

    1998-01-01

    Riigikogu ei kinnitanud autode aktsiisi tõstmise seaduseelnõud, mistõttu järgmise aasta riigieelarvesse tekkis 300 miljoni kroonine puudujääk. Ilmunud ka: Kupetsheskaja Gavan : Gazeta Vzgljad, 5. nov. 1998, lk. 10

  14. Lahkunud maailmaparandaja Robert Lepikson jäi igavesti otsijaks / Kai Kalamees

    Index Scriptorium Estoniae

    Kalamees, Kai

    2006-01-01

    Ülevaade riigikogu liikme, endise siseministri, Tallinna linnapea ja Võru maavanema Robert Lepiksoni elukäigust, meenutused tuntud ühiskonnategelastelt. Lisad: Robert Lepikson; Kõva sõnaga mees. Vt. samas: Turvavaatleja vastutusrikas töö viimasel rallil; Ivar Raidam: Lepiksoni panus autosporti oli tohutu; Hans H. Luik: Respect, Robert!

  15. Arnold Rüütel rikkus betoonpaneelidest kai ehitamisega seadust / Oliver Rand

    Index Scriptorium Estoniae

    Rand, Oliver, 1971-

    2007-01-01

    Laimjala vallas Saarekülas president Arnold Rüütli omavolilist ehitustegevust kontrollimas käinud keskkonnainspektorid leidsid, et paadisilla rajamiseks oleks president pidanud taotlema erikasutusluba. Ilmunud ka: Meie Maa (2007) 24. aug. 2007, lk. 1

  16. Eestis on juba puudu üle 400 IT-spetsialisti / Kai Simson

    Index Scriptorium Estoniae

    Simson, Kai

    2006-01-01

    Cisco Systemsi poolt 31 Ida- ja Lääne-Euroopa riigis tehtud uuringu kohaselt on Eesti IT-spetsialistidega varustatuse paremusjärjestuses alles 28. kohal. Vt. samas lühiintervjuud e-Riigi Akadeemia direktori Ivar Talloga

  17. Putini küllakutse tekitab Tallinnale ja Vilniusele peavalu / Kai Kalamees

    Index Scriptorium Estoniae

    Kalamees, Kai

    2005-01-01

    Leedu ametlikud allikad kummutasid uudise president Adamkuse otsusest Moskva visiidist loobumise kohta. Baltimaade presidentide koostööst. Lisa: Poola taotleb MRP hukkamõistu. Vt. samas intervjuud presidendi sisenõuniku Mart Siimanniga

  18. Lennujaama kontor nüüd nõukogudeaegses terminalis / Kai Ilustrumm

    Index Scriptorium Estoniae

    Ilustrumm, Kai

    2004-01-01

    Tallinna Lennujaama hoone rekonstrueerimine läks maksma üle 20 milj. Eesti krooni. Kolmandiku hoonest hõlmavad kontoriruumid, ülejäänud osa saab kasutada mitmesuguste ürituste teenindamiseks. Renoveerimisplaani kavandasid Andres ja Reet Põime, sisekujunduse Tiiu Raudsepp-Truus

  19. Hüplevad aktsiisid teevad ettevõtjaile meelehärmi / Kai Kalamees

    Index Scriptorium Estoniae

    Kalamees, Kai

    2005-01-01

    Vähem kui aasta jooksul on riik kaks korda muutnud alkoholi- ja tubakaaktsiisi tõusu graafikut. Scandinavian Tobacco Eesti tegevjuhi Juhan Mati sõnul ei tekita tihedad muutmised kindlust, uus hinnatõus kätkeb tema sõnul ka salasuitsude leviku ohtu. Tubaka- ja alkoholiaktsiisi muudatusi käsitlevast seaduseelnõust

  20. Piimaäri keerleb ümber juustu ja jogurti / Kai Vare

    Index Scriptorium Estoniae

    Vare, Kai, 1968-

    2004-01-01

    Tihe konkurents piimaturul sunnib piimakombinaate oma tooteid pidevalt uuendama. Piimatööstuste juhid kommenteerivad inimeste piimatoodetega seotud tarbimisharjumusi. Diagrammid: Piimatoodete ekspordimaht kahanemas; Juustu ja või tootmine ületas mõõna. Vt. samas: Peatähelepanu pöördub teismelisele tarbijale; Valio Eesti AS; AS Rakvere Piim; Tallinn Piimatööstuse AS; Piimandusühistu E-Piim; AS Põlva Piim; AS Võru Juust

  1. Fix iT 2014 ehk talgud massidesse / Kai Raku, Vanessa Moreno

    Index Scriptorium Estoniae

    Raku, Kai

    2014-01-01

    Eesti Erinoorsootöö Ühing noOR vahendab ja võõrustab erivajadustega noori vabatahtlikus teenistuses, üheks nende partneriks on Hispaanias asuv Associacion Cultural En-Construccion, mille juht Vanessa Moreno tutvustab Associacion Cultural En-Construccioni tegevust ja puuetega inimeste vabatahtliku teenistuse võimalusi

  2. Light-Dependent Expression of Four Cryptic Archaeal Circadian Gene Homologs

    Directory of Open Access Journals (Sweden)

    Michael eManiscalco

    2014-03-01

    Full Text Available Circadian rhythms are important biological signals that have been found in almost all major groups of life from bacteria to man, yet it remains unclear if any members of the second major prokaryotic domain of life, the Archaea, also possess a biological clock. To investigate this question, we examined the regulation of four cyanobacterial-like circadian gene homologs present in the genome of the haloarchaeon Haloferax volcanii. These genes, designated cirA, cirB, cirC, and cirD, display similarity to the KaiC-family of cyanobacterial clock proteins, which act to regulate rhythmic gene expression and to control the timing of cell division. Quantitative RT-PCR analysis was used to examine the expression of each of the four cir genes in response to 12 h light/12 h dark cycles (LD 12:12 during balanced growth in H. volcanii. Our data reveal that there is an approximately two to sixteen-fold increase in cir gene expression when cells are shifted from light to constant darkness and this pattern of gene expression oscillates with the light conditions in a rhythmic manner. Targeted single- and double-gene knockouts in the H. volcanii cir genes results in disruption of light-dependent, rhythmic gene expression, although it does not lead to any significant effect on growth under these conditions. Restoration of light-dependent, rhythmic gene expression was demonstrated by introducing, in trans, a wild-type copy of individual cir genes into knockout strains. These results are noteworthy as this is the first attempt to characterize the transcriptional expression and regulation of the ubiquitous kaiC homologs found among archaeal genomes.

  3. Contención sin aislamiento

    Directory of Open Access Journals (Sweden)

    Mario Sánchez Gumiel

    2013-02-01

    Full Text Available En febrero de 2012 se cumplieron cuarenta años de la visita de Richard Nixon a China y, por tanto, de la reanudación de las relaciones sino-americanas que habían sido interrumpidas en 1949. Desde entonces, Estados Unidos y China han mantenido una recíproca política de contención y aislamiento, conscientes de sus diferencias, pero sabedores también de la necesidad de un entendimiento mutuo. Como consecuencia dicha política de contención y aislamiento, el océano Pacífico está transformándose, como el Atlántico después de la Segunda Guerra Mundial, en el nuevo escenario geopolítico del siglo XXI.Palabras Clave: Estados Unidos, China, Nixon, Mao, Deng Xiaoping, Taiwán, Chiang Kai-Shek, Contención, Aislamiento, Corea, Vietnam, Tian’anmen, URSS, Comunismo, Capitalismo.___________________Abstract:On February 2012 took place the fourtieth anniversary of President Nixon’s visiting to China and, as a consequence, of the resumption of the Sino-American relations which had been interrupted in 1949. Since then, the United States and China have experienced a reciprocal policy of containment without isolation, both being aware of their mutual differences but knowing of the necessity of mutual understanding as well. As a result, the Pacific ocean is making changes, just as the Atlantic after the Second World War, in order to become the new geopolitical place of the Twenty First century.Keywords: United States, China, Nixon, Mao, Deng Xiaoping, Taiwán, Chiang Kai-Shek, Containment, Isolation, Korea, Vietnam, Tian’anmen, USSR, Communism, Capitalism.

  4. К вопросу о связи вопросительных и условных конструкций в древнелитовском языке

    Directory of Open Access Journals (Sweden)

    Vincentas Drotvinas

    2011-05-01

    Full Text Available DĖL KLAUSIAMŲJŲ IR SĄLYGOS KONSTRUKCIJŲ RYŠIO SENUOSIUOSE LIETUVIŲ RAŠTUOSEReziumėSenųjų lietuvių kalbos raštų faktai rodo, kad postpozicinė dalelytė gu, be klausiamosios ar skiriamosios reikšmės, kartais atlieka sąlygos jungtuko funkciją (norigu — jei nori.Taip pat ir sąlygos jungtukas jei gali būti vartojamas skiriamąja arba klausiamąja reikšmėmis (jei — argu, ar. Minimą jungtuko jei reikšmę rodo ir kai kurie lietuvių kalbos tarmių faktai.

  5. Grūdų kainų kitimo tendencijos Lietuvoje 2006–2010 metais

    OpenAIRE

    Bradūnas, Vidmantas

    2011-01-01

    Straipsnyje nagrinėjami Lietuvos grūdų rinkoje vykstantys ekonominiai procesai bei jų poveikis grūdų supirkimo kainų kitimo tendencijoms. 2006 metai augalininkystės sektoriui buvo labai nepalankūs, 2007–2009 metais žymiai padidėjo augalų derlingumas ir derlius, o 2010-ieji dėl nepalankių klimatinių sąlygų buvo nederlingi – javų derlingumas, palyginti su 2009 metais, sumažėjo 20,3 proc. Lietuvos grūdų rinka labiausiai priartėjusi prie monopolinės konkurencijos sąlygų, ir grūdų kainas teoriškai...

  6. The efficiency of the advertising tools of the commercial enterprise

    OpenAIRE

    Česnulevičius, Kęstutis

    2008-01-01

    Magistro darbe tiriamas reklamos priemonių efektyvumas komercinėje įmonėje. Magistro darbo tyrimo objektas – UAB „Inarta“ reklamos priemonių efektyvumas. Magistro darbo tikslas – išnagrinėti reklamos efektyvumą UAB „Inarta“ ir parengti jos gerinimo planą. Darbo tyrimo hipotezė – reklamos priemonių efektyvumą lemia ne tik išlaidos reklamai, bet teisingas priemonių pasirinkimas įmonės veiklai reklamuoti. O taip pat teorinės ir praktinės sąsajos supratimas – kaip įmonė supranta šią sąsają ir kai...

  7. Links between femininity ideology and adolescent girls‘ depresive symptoms, self-esteem and subjective life satisfaction

    OpenAIRE

    Erentaitė, Rasa; Malinauskienė, Oksana

    2012-01-01

    Mokslinė problema. Tyrimai rodo, kad kai kurie paauglių merginų perimamos moteriškumo sampratos aspektai gali būti nepalankūs jų psichikos sveikatai, t. y. būti susiję su aukštesniais psichologinių sunkumų ir žemesniais gerovės rodikliais. Tačiau lieka neaišku, kiek tai aktualu vėlyvojoje paauglystėje, kokie psichologinių sunkumų ir gerovės rodikliai yra susiję su moteriškumo ideologija bei kiek šie ryšiai svarbūs Lietuvos kontekste. Tikslas. Šiame darbe siekiama nustatyti paauglių moteriškum...

  8. The conceptualism of emotional marketing

    OpenAIRE

    Zuikauskienė, Rasa

    2009-01-01

    Pastarojoje moderniojo marketingo eroje, kuomet ypatingas dėmesys yra skiriamas įmonių santykių su pirkėjais kūrimui bei jų palaikymui bei vis didėjant konkurencinei kovai dėl pirkėjų dėmesio, tobulėjant technologijoms, tampa gyvybiškai svarbu įvaldyti kiekvieną veiksnį, galintį įtakoti pritraukiant ir išlaikant pirkėją. Šis naujas veiksnys galėtų būti vartotojų emocijos. Būtent iš poreikio surasti naują konkurencinį veiksnį atsirado emocinis marketingas. Šio darbo tikslas – nustatyti emocini...

  9. Elektroninių dokumentų apyvartos teisinis reglamentavimas

    OpenAIRE

    Dranseikienė, Jolanta

    2005-01-01

    Šiuolaikinė visuomenė neįsivaizduojama be modernių informacijos apdorojimo, perdavimo, saugojimo priemonių. Įstatymai tradiciškai reikalauja „rašytinių“, „pasirašytų“, „originalių“ popierinių dokumentų, tai sukelia neaiškumų dėl dokumentų perteiktų elektronine forma teisinės reikšmės ir galios. Šiame darbe apibrėžiama e. dokumento sąvoka, teisinės galios aspektai, aptariama kokiomis priemonėmis e. dokumentui suteiktas teisinis pripažinimas ES šalių, Rusijos, Lietuvos, UNCITRAL dokumentuose. E...

  10. A second polymorph of [1,2-bis(di-tert-butylphosphinoethane]dichloridoplatinum(II

    Directory of Open Access Journals (Sweden)

    William D. Jones

    2008-03-01

    Full Text Available The title complex, [PtCl2(C18H40P2], contains a PtII center in an approximately square-planar geometry [cis angle range = 88.09 (3–91.39 (3°; twist angle = 1.19 (5°]. The Pt—P bond lengths of 2.2536 (8 and 2.2513 (8 Å and the Pt—Cl bond lengths of 2.3750 (8 and 2.3588 (8 Å are normal. This crystal form is a polymorph of a structure reported previously [Harada, Kai, Yasuoka & Kasai (1976. Bull. Chem. Soc. Jpn, 49, 3472–3477].

  11. Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3-Phenyl-1,4-benzothiazine Analogues.

    Science.gov (United States)

    Felicetti, Tommaso; Cannalire, Rolando; Burali, Maria Sole; Massari, Serena; Manfroni, Giuseppe; Barreca, Maria Letizia; Tabarrini, Oriana; Schindler, Bryan D; Sabatini, Stefano; Kaatz, Glenn W; Cecchetti, Violetta

    2017-08-22

    Bacterial resistance to antimicrobial agents has become an increasingly serious health problem in recent years. Among the strategies by which resistance can be achieved, overexpression of efflux pumps such as NorA of Staphylococcus aureus leads to a sub-lethal concentration of the antibacterial agent at the active site that in turn may predispose the organism to the development of high-level target-based resistance. With an aim to improve both the chemical stability and potency of our previously reported 3-phenyl-1,4-benzothiazine NorA inhibitors, we replaced the benzothiazine core with different nuclei. None of the new synthesized compounds showed any appreciable intrinsic antibacterial activity, and, in particular, 2-(3,4-dimethoxyphenyl)quinoline (6 c) was able to decrease, in a concentration-dependent manner, the ciprofloxacin MIC against the norA-overexpressing strains S. aureus SA-K2378 (norA++) and SA-1199B (norA+/A116E GrlA). © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. From phenothiazine to 3-phenyl-1,4-benzothiazine derivatives as inhibitors of the Staphylococcus aureus NorA multidrug efflux pump.

    Science.gov (United States)

    Sabatini, Stefano; Kaatz, Glenn W; Rossolini, Gian Maria; Brandini, David; Fravolini, Arnaldo

    2008-07-24

    Overexpression of efflux pumps is an important mechanism by which bacteria evade effects of substrate antimicrobial agents and inhibition of such pumps is a promising strategy to circumvent this resistance mechanism. NorA is a Staphylococcus aureus multidrug efflux pump, the activity of which confers decreased susceptibility to many structurally unrelated agents, including fluoroquinolones, resulting in a multidrug resistant (MDR) phenotype. In this work, a series of 1,4-benzothiazine derivatives were designed and synthesized as a minimized structural template of phenothiazine MDR efflux pump inhibitors (EPIs) in an effort to identify more potent S. aureus NorA EPIs. Almost all derivatives evaluated showed good activity in combination with ciprofloxacin against S. aureus ATCC 25923; some were capable of completely restoring ciprofloxacin activity in a norA-overexpressing strain (SA-K2378). Compounds 6k and 7j displayed good activity against SA-1199B, a strain that also overexpresses norA, in an ethidium bromide (EtBr) efflux inhibition assay.

  13. Evolution from a natural flavones nucleus to obtain 2-(4-Propoxyphenyl)quinoline derivatives as potent inhibitors of the S. aureus NorA efflux pump.

    Science.gov (United States)

    Sabatini, Stefano; Gosetto, Francesca; Manfroni, Giuseppe; Tabarrini, Oriana; Kaatz, Glenn W; Patel, Diixa; Cecchetti, Violetta

    2011-08-25

    Overexpression of efflux pumps is an important mechanism by which bacteria evade the effects of substrate antimicrobial agents. Inhibition of such pumps is a promising strategy to circumvent this resistance mechanism. NorA is a Staphylococcus aureus efflux pump that confers reduced susceptibility to many structurally unrelated agents, including fluoroquinolones, resulting in a multidrug resistant phenotype. In this work, a series of 2-phenyl-4(1H)-quinolone and 2-phenyl-4-hydroxyquinoline derivatives, obtained by modifying the flavone nucleus of known efflux pump inhibitors (EPIs), were synthesized in an effort to identify more potent S. aureus NorA EPIs. The 2-phenyl-4-hydroxyquinoline derivatives 28f and 29f display potent EPI activity against SA-1199B, a strain that overexpresses norA, in an ethidium bromide efflux inhibition assay. The same compounds, in combination with ciprofloxacin, were able to completely restore its antibacterial activity against both S. aureus SA-K2378 and SA-1199B, norA-overexpressing strains. © 2011 American Chemical Society

  14. Re-evolution of the 2-phenylquinolines: ligand-based design, synthesis, and biological evaluation of a potent new class of Staphylococcus aureus NorA efflux pump inhibitors to combat antimicrobial resistance.

    Science.gov (United States)

    Sabatini, Stefano; Gosetto, Francesca; Iraci, Nunzio; Barreca, Maria Letizia; Massari, Serena; Sancineto, Luca; Manfroni, Giuseppe; Tabarrini, Oriana; Dimovska, Mirjana; Kaatz, Glenn W; Cecchetti, Violetta

    2013-06-27

    Overexpression of efflux pumps is an important mechanism by which bacteria evade the effects of antimicrobial agents that are substrates. NorA is a Staphylococcus aureus efflux pump that confers reduced susceptibility to many structurally unrelated agents, including fluoroquinolones, biocides, and dyes, resulting in a multidrug resistant (MDR) phenotype. In this work, a series of 2-phenylquinoline derivatives was designed by means of ligand-based pharmacophore modeling in an attempt to identify improved S. aureus NorA efflux pump inhibitors (EPIs). Most of the 2-phenylquinoline derivatives displayed potent EPI activity against the norA overexpressing strain SA-1199B. The antibacterial activity of ciprofloxacin, when used in combination with some of the synthesized compounds, was completely restored in SA-1199B and SA-K2378, a strain overexpressing norA from a multicopy plasmid. Compounds 3m and 3q also showed potent synergistic activity with the ethidium bromide dye in a strain overexpressing the MepA MDR efflux pump.

  15. Editorial

    CERN Multimedia

    Staff Association

    2012-01-01

    For its fiftieth anniversary the Kindergarten and School run by the Staff Association   is in better shape than ever. The CERN site has resounded for 50 years with the joyful shouts of the children there. It is indeed in this joyful and multicultural atmosphere than many generations of children of CERN staff have followed one another all those years. Operating on one of the most beautiful sites of CERN and supervised by competent and creative professionals, the children learn through play, the basics needed for their integration into society and entry into academic learning. Active learning is the heart of the action.  Children take in knowledge as they develop and are exposed to multiple experiences. The activities proposed in the SAKS are based on a global approach to development as well as on values such as self-respect, respect towards others, the environment, autonomy, sharing, cooperation, communication and creativity. In the large, specially designed garden surrounding...

  16. Üst havayolları için mür tentürü, nane yağı ve mentol kombinasyonu içeren bir pastil

    OpenAIRE

    Öktemer, Tuğba; İpçi, Kağan; Bayar Muluk, Nuray; Cingi, Cemal

    2016-01-01

    Mür ve boraks içerek tentürler gargara solüsyonu olarak kullanılmaktadır. Mür sakızı, sindirim güçlüğü, ülserler, soğuk algınlığı, öksürük, astım, akciğer konjesyonu, artrit ağrısı ve kanser için de kullanılır. Mür, ağrıya tabi tutulan farelerde, ağrı kesici etkiler göstermiştir. Antiseptik olarak ağız ve boğaz inşamatuar lezyonlarında kullanılır. Boğaz ve ağzın iltihaplı lezyonlara uygulanır ve antispazmodik olarak kanser ve enfeksiyon hastalıklarının tedavisi için kullanılır. Bu yazıda mür ...

  17. Tinjauan Hukum Islam terhadap Perkawinan Beda Kelas Muslim Sasak di Lombok

    Directory of Open Access Journals (Sweden)

    Basriadi Basriadi

    2015-08-01

    Full Text Available This article attempts to examine in depth, based on the theory of kafâ‘ah, different class marriages in the Sasak Muslim community, Lombok. The study concludes that on one hand, the different class marriages between noblewomen and non-noblemen do not have an impact on the purpose of marriage which is to create sakînah, mawaddah, and rahmah household. On the other hand, the marriage that is based on Islamic values is able to realize a happy and harmonious household regardless of social status background. The most important thing in domestic life is communication and trust between husbands and wives. In fiqh munâkah}ât, it is required when someone is looking for a spouse, something that needs to be seen is lineage, beauty, wealth and religion. This article would like to emphasize that there is no prohibition in Islam to marry people of different social class.

  18. PEMANFAATAN NERACA SEBAGAI PENERAPAN FUNGSI PENGELOLAAN PERMODALAN UMKM (HASIL PEMIKIRAN KONSEPTUAL

    Directory of Open Access Journals (Sweden)

    Lufthia Sevriana

    2016-10-01

      Tujuan Penelitian ini adalah untuk menjadi salah satu kontribusi bagi Usaha Mikro, Kecil dan Menengah karena kepedulian penulis pada kondisi UMKM dalam mengembangkan bisnisnya. Karakteristik dari permasalahan mereka sangat klasik. Kebanyakan UMKM masih tidak mampi mengelola modal mereka, mengambil manfaat dari teknologi untuk bisnis mereka, untuk memperluas jaringan pemasaran produknya, dan lain sebagainya. Akan tetapi, modal sebagai kebutuhan mendasar dari operasional bisnis mereka, membutuhkan perlakuan khusus. Dari kajian pustaka, penulis menemukan bahwa meskipun UMKM mengetahui manfaat dari penyusunan laporan keuangan, kebanyakan dari mereka tidak memiliki kemauan untuk menyusun laporan keuangan dengan komitmen yang kuat. Meskipun kita telah memasuki era MEA, kompetensi dalam penyusunan laporan keuangan tidak tedistribusi dengan rata diantara negara-negara Asean. Untuk itu, UMKM membutuhkan dukungan dari pemerintah, perusahaan dan juga akademisi untuk melatih pengusaha UMKM, dan juga untuk membimbing mereka dalam meningkatkan kompetensi dalam penyusunan laporan keuangan berdasarkan tahapan yan sudah mereka terapkan.   Kata Kunci: UMKM, Laporan Keuangan, SAK ETAP

  19. Production of proinflammatory cytokines without invocation of cytotoxic effects by an Epstein-Barr virus-infected natural killer cell line established from a patient with hypersensitivity to mosquito bites.

    Science.gov (United States)

    Suzuki, Daisuke; Tsuji, Kazuhide; Yamamoto, Takenobu; Fujii, Kazuyasu; Iwatsuki, Keiji

    2010-10-01

    Cumulative evidence supports that Epstein-Barr virus (EBV)-infected natural killer (NK) cells induce severe systemic and cutaneous inflammation in patients with hypersensitivity to mosquito bites (HMB). In order to understand the pathogenesis of HMB, we established an EBV-infected cell line and characterized the cytological profiles. A novel EBV-infected NK-cell line, designated NKED, was established from a patient with HMB and used for the present study along with two other NK-cell lines, KAI3 and KHYG-1. NKED expressed the latency II-related transcripts. NKED cells were positive for CD2 and CD161 antigens, and negative for CD3, CD16, CD34, CD56, and T-cell receptor α/β and γ/δ antigens. Although NKED cells contained several cytotoxic molecules, the cells had an extremely poor cytotoxic activity. The majority of NKED cells were negative for perforin, major histocompatibility complex class I-restricted NK-cell receptors, CD94 and KIR2D, and an activating receptor, NKG2D. NKED cells, however, secreted higher levels of tumor necrosis factor-α. Stimulation with phorbol 12-myristate 13-acetate or tumor necrosis factor-α induced expression of BZLF1 messenger RNA in the NKED and KAI3 cells, indicating the transition from the latent- to the lytic-cycle infection. These data suggested that NKED cells revealed a very low cytotoxic effect probably because of the low expression levels of perforin, but had the ability to release proinflammatory cytokines. NKED cells did not reflect the characteristics of HMB, as they were different from pathogenic NK cells proliferating in the HMB patient, but the difference indicated that pathogenic NK cells could change their character in the presence of interleukin-2. Copyright © 2010 ISEH - Society for Hematology and Stem Cells. Published by Elsevier Inc. All rights reserved.

  20. CTGF enhances resistance to 5-FU-mediating cell apoptosis through FAK/MEK/ERK signal pathway in colorectal cancer

    Directory of Open Access Journals (Sweden)

    Yang K

    2016-11-01

    Full Text Available Kai Yang, Kai Gao, Gui Hu, Yanguang Wen, Changwei Lin, Xiaorong Li Department of General Surgery, The Third Affiliated Hospital of Central South University, Central South University, Changsha, Hunan, People’s Republic of China Abstract: Colorectal cancer (CRC is one of the most commonly diagnosed cancers among both males and females; the chemotherapy drug 5-fluorouracil (5-FU is one of a doctors’ first lines of defense against CRC. However, therapeutic failures are common because of the emergence of drug resistance. Connective tissue growth factor (CTGF is a secreted protein that binds to integrins, and regulates the invasiveness and metastasis of certain carcinoma cells. Here, we found that CTGF was upregulated in drug-resistant phenotype of human CRC cells. Overexpression of CTGF enhanced the resistance to 5-FU-induced cell apoptosis. Moreover, downregulating the expression of CTGF promoted the curative effect of chemotherapy and blocked the cell cycle in the G1 phase. We also found that CTGF facilitated resistance to 5-FU-induced apoptosis by increasing the expression of B-cell lymphoma-extra large (Bcl-xL and survivin. Then we pharmacologically blocked MEK/ERK signal pathway and assessed 5-FU response by MTT assays. Our current results indicate that the expression of phosphorylated forms of MEK/ERK increased in high CTGF expression cells and MEK inhibited increases in 5-FU-mediated apoptosis of resistant CRC cells. Therefore, our data suggest that MEK/ERK signaling contributes to 5-FU resistance through upstream of CTGF, and supports CRC cell growth. Comprehending the molecular mechanism underlying 5-FU resistance may ultimately aid the fight against CRC. Keywords: connective tissue growth factor, 5-fluorouracil, mitogen-activated protein kinase/extracellular regulated protein kinases, phosphatidyl inositol 3-kinase/serine/threonine kinase Akt, colorectal cancer